locus-tag	class	description
RAM_RS00010	COG0592	DNA-directed DNA polymerase activity
RAM_RS00015	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
RAM_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
RAM_RS00025	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
RAM_RS00030	COG0187	DNA topoisomerase II activity
RAM_RS00180	COG0705	Rhomboid family
RAM_RS00180	COG0457	Tetratricopeptide repeat
RAM_RS00195	COG3764	Sortase (surface protein transpeptidase)
RAM_RS00225	COG2197	response regulator
RAM_RS00255	COG0515	serine threonine protein kinase
RAM_RS00255	COG2815	serine threonine protein kinase
RAM_RS00260	COG0515	serine threonine protein kinase
RAM_RS00265	COG0768	penicillin binding
RAM_RS00280	COG1716	ATPase activity
RAM_RS00285	COG1716	ATPase activity
RAM_RS00315	COG0626	cystathionine gamma-synthase activity
RAM_RS00335	COG2186	Transcriptional regulator
RAM_RS00340	COG0747	negative chemotaxis
RAM_RS00350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RAM_RS00355	COG0444	Belongs to the ABC transporter superfamily
RAM_RS00360	COG4608	Belongs to the ABC transporter superfamily
RAM_RS00365	COG1012	belongs to the aldehyde dehydrogenase family
RAM_RS00370	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS00375	COG0154	amidase activity
RAM_RS00380	COG3547	Transposase (IS116 IS110 IS902 family)
RAM_RS00400	COG2301	Belongs to the HpcH HpaI aldolase family
RAM_RS00410	COG0702	epimerase
RAM_RS00415	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
RAM_RS00430	COG1309	transcriptional regulator
RAM_RS00440	COG2211	Major facilitator Superfamily
RAM_RS00470	COG2372	response to copper ion
RAM_RS00470	COG1276	copper resistance
RAM_RS00485	COG1174	glycine betaine transport
RAM_RS00495	COG1174	glycine betaine transport
RAM_RS00520	COG2226	methyltransferase
RAM_RS00530	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
RAM_RS00535	COG0405	Gamma-glutamyltransferase
RAM_RS00545	COG5433	transposase activity
RAM_RS00560	COG0477	Major facilitator Superfamily
RAM_RS00570	COG4585	Histidine kinase
RAM_RS00575	COG2197	response regulator
RAM_RS00605	COG0438	transferase activity, transferring glycosyl groups
RAM_RS00660	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
RAM_RS00665	COG3275	phosphorelay sensor kinase activity
RAM_RS00690	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RAM_RS00695	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
RAM_RS00695	COG0425	Belongs to the sulfur carrier protein TusA family
RAM_RS00715	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
RAM_RS00735	COG1191	sigma factor activity
RAM_RS00825	COG1271	oxidase subunit
RAM_RS00830	COG1294	oxidase, subunit
RAM_RS00835	COG4988	ABC transporter
RAM_RS00890	COG4715	Zinc finger, swim domain protein
RAM_RS00900	COG1072	(Pantothenic acid kinase))
RAM_RS00905	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
RAM_RS00915	COG0406	alpha-ribazole phosphatase activity
RAM_RS00950	COG0754	glutathionylspermidine amidase activity
RAM_RS00960	COG0596	Alpha beta hydrolase
RAM_RS00965	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
RAM_RS00970	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
RAM_RS00980	COG0579	oxidoreductase
RAM_RS01005	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
RAM_RS01020	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
RAM_RS01050	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
RAM_RS01060	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS01065	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_RS01110	COG0561	phosphatase activity
RAM_RS01115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RAM_RS01135	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
RAM_RS01150	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS01155	COG0277	FAD linked oxidase domain protein
RAM_RS01165	COG1216	Glycosyl transferase, family 2
RAM_RS01195	COG1216	Glycosyl transferase, family 2
RAM_RS01220	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS01220	COG0604	alcohol dehydrogenase
RAM_RS01220	COG3321	synthase
RAM_RS01225	COG2234	aminopeptidase activity
RAM_RS01285	COG4565	transcriptional regulatory protein
RAM_RS01290	COG3290	protein histidine kinase activity
RAM_RS01295	COG1116	anion transmembrane transporter activity
RAM_RS01320	COG1672	PFAM Archaeal ATPase
RAM_RS01320	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
RAM_RS01335	COG1522	sequence-specific DNA binding
RAM_RS01340	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
RAM_RS01350	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
RAM_RS01355	COG2186	Transcriptional regulator
RAM_RS01370	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
RAM_RS01380	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RAM_RS01410	COG3469	chitinase activity
RAM_RS01415	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
RAM_RS01440	COG3583	domain protein
RAM_RS01440	COG3584	3D domain protein
RAM_RS01515	COG3559	Exporter of polyketide antibiotics
RAM_RS01520	COG1131	(ABC) transporter
RAM_RS01575	COG0287	Prephenate dehydrogenase
RAM_RS01580	COG1902	pentaerythritol trinitrate reductase activity
RAM_RS01580	COG0446	pyridine nucleotide-disulphide oxidoreductase
RAM_RS01600	COG1846	Transcriptional regulator
RAM_RS01630	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
RAM_RS01640	COG2318	DinB family
RAM_RS01650	COG0194	GDP metabolic process
RAM_RS01710	COG0515	serine threonine protein kinase
RAM_RS01725	COG0028	Belongs to the TPP enzyme family
RAM_RS01740	COG3199	ATP-NAD kinase
RAM_RS01745	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
RAM_RS01760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RAM_RS01765	COG0515	serine threonine protein kinase
RAM_RS01940	COG2226	methyltransferase
RAM_RS01980	COG2233	PERMEase
RAM_RS01985	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
RAM_RS01995	COG1414	Transcriptional regulator
RAM_RS02015	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
RAM_RS02105	COG2515	1-aminocyclopropane-1-carboxylate deaminase
RAM_RS02130	COG2364	Membrane
RAM_RS02135	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RAM_RS02150	COG2733	membrane
RAM_RS02170	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
RAM_RS02205	COG2986	histidine ammonia-lyase
RAM_RS02235	COG1174	glycine betaine transport
RAM_RS02250	COG1846	Transcriptional regulator
RAM_RS02260	COG2130	NADP-dependent
RAM_RS02275	COG1064	alcohol dehydrogenase
RAM_RS02305	COG0812	UDP-N-acetylmuramate dehydrogenase activity
RAM_RS02320	COG0438	transferase activity, transferring glycosyl groups
RAM_RS02335	COG0588	phosphoglycerate mutase activity
RAM_RS02345	COG0667	Aldo Keto reductase
RAM_RS02350	COG5002	protein histidine kinase activity
RAM_RS02380	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
RAM_RS02400	COG4585	Histidine kinase
RAM_RS02425	COG1595	DNA-templated transcription, initiation
RAM_RS02430	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_RS02445	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
RAM_RS02450	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
RAM_RS02455	COG0181	hydroxymethylbilane synthase activity
RAM_RS02460	COG1648	precorrin-2 dehydrogenase activity
RAM_RS02460	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
RAM_RS02495	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RAM_RS02500	COG0577	efflux transmembrane transporter activity
RAM_RS02500	COG1136	(ABC) transporter
RAM_RS02505	COG1136	(ABC) transporter
RAM_RS02505	COG0577	efflux transmembrane transporter activity
RAM_RS02520	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
RAM_RS02525	COG0406	alpha-ribazole phosphatase activity
RAM_RS02530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RAM_RS02535	COG0785	Cytochrome C biogenesis protein
RAM_RS02545	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
RAM_RS02565	COG1522	sequence-specific DNA binding
RAM_RS02595	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
RAM_RS02620	COG0438	transferase activity, transferring glycosyl groups
RAM_RS02635	COG2226	methyltransferase
RAM_RS02650	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RAM_RS02655	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RAM_RS02660	COG0649	NAD binding
RAM_RS02675	COG1034	ATP synthesis coupled electron transport
RAM_RS02680	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
RAM_RS02685	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RAM_RS02690	COG0839	Belongs to the complex I subunit 6 family
RAM_RS02695	COG0713	ATP synthesis coupled electron transport
RAM_RS02700	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
RAM_RS02710	COG1007	ATP synthesis coupled electron transport
RAM_RS02735	COG0142	geranyltranstransferase activity
RAM_RS02750	COG1013	pyruvate-flavodoxin oxidoreductase activity
RAM_RS02755	COG0674	pyruvate-flavodoxin oxidoreductase activity
RAM_RS02755	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
RAM_RS02765	COG1522	sequence-specific DNA binding
RAM_RS02770	COG1834	amidinotransferase
RAM_RS02785	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
RAM_RS02790	COG0438	transferase activity, transferring glycosyl groups
RAM_RS02805	COG0367	asparagine synthase
RAM_RS02850	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
RAM_RS02855	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
RAM_RS02865	COG1215	transferase activity, transferring glycosyl groups
RAM_RS02875	COG4310	Domain of unknown function (DUF2172)
RAM_RS02890	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
RAM_RS02905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RAM_RS02920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RAM_RS02925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RAM_RS02945	COG1666	GTP binding
RAM_RS02965	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
RAM_RS02995	COG0267	Belongs to the bacterial ribosomal protein bL33 family
RAM_RS03000	COG2030	dehydratase
RAM_RS03020	COG1725	Transcriptional regulator
RAM_RS03050	COG0081	regulation of translation
RAM_RS03055	COG2267	carboxylic ester hydrolase activity
RAM_RS03085	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
RAM_RS03110	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
RAM_RS03135	COG0673	inositol 2-dehydrogenase activity
RAM_RS03155	COG3321	synthase
RAM_RS03155	COG0604	alcohol dehydrogenase
RAM_RS03175	COG0604	alcohol dehydrogenase
RAM_RS03175	COG3321	synthase
RAM_RS03195	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
RAM_RS03200	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
RAM_RS03215	COG0546	phosphoglycolate phosphatase activity
RAM_RS03225	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
RAM_RS03230	COG0657	acetylesterase activity
RAM_RS03235	COG0477	Major facilitator Superfamily
RAM_RS03250	COG2124	cytochrome p450
RAM_RS03255	COG2124	cytochrome p450
RAM_RS03275	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RAM_RS03290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RAM_RS03315	COG2124	cytochrome p450
RAM_RS03325	COG3959	Transketolase, thiamine diphosphate binding domain
RAM_RS03330	COG3958	Transketolase
RAM_RS03340	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
RAM_RS03355	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
RAM_RS03365	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
RAM_RS03370	COG1522	sequence-specific DNA binding
RAM_RS03375	COG0477	Major facilitator Superfamily
RAM_RS03385	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RAM_RS03385	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RAM_RS03430	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
RAM_RS03435	COG0049	tRNA binding
RAM_RS03440	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
RAM_RS03450	COG0051	transcription antitermination factor activity, RNA binding
RAM_RS03455	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
RAM_RS03460	COG0088	Forms part of the polypeptide exit tunnel
RAM_RS03465	COG0089	rRNA binding
RAM_RS03470	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
RAM_RS03475	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
RAM_RS03480	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
RAM_RS03485	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
RAM_RS03490	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
RAM_RS03495	COG0255	Belongs to the universal ribosomal protein uL29 family
RAM_RS03500	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
RAM_RS03505	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
RAM_RS03510	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
RAM_RS03515	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
RAM_RS03525	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
RAM_RS03530	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
RAM_RS03535	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
RAM_RS03540	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
RAM_RS03545	COG1841	ribosomal large subunit assembly
RAM_RS03550	COG0200	Binds to the 23S rRNA
RAM_RS03560	COG1280	lysine exporter protein (LysE YggA)
RAM_RS03570	COG0563	adenylate kinase activity
RAM_RS03580	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
RAM_RS03585	COG0257	Belongs to the bacterial ribosomal protein bL36 family
RAM_RS03600	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
RAM_RS03605	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
RAM_RS03610	COG0202	RNA polymerase activity
RAM_RS03615	COG0203	ribosomal protein L17
RAM_RS03620	COG0101	tRNA pseudouridine synthase activity
RAM_RS03655	COG1404	Belongs to the peptidase S8 family
RAM_RS03665	COG1674	ftsk spoiiie
RAM_RS03670	COG0443	Heat shock 70 kDa protein
RAM_RS03700	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
RAM_RS03705	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
RAM_RS03710	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
RAM_RS03720	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_RS03760	COG1349	DNA-binding transcription factor activity
RAM_RS03765	COG1070	Carbohydrate kinase
RAM_RS03770	COG3842	ATPase activity
RAM_RS03775	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
RAM_RS03785	COG0802	atpase or kinase
RAM_RS03795	COG0825	malonyl-CoA metabolic process
RAM_RS03795	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
RAM_RS03800	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_RS03810	COG0456	acetyltransferase
RAM_RS03815	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
RAM_RS03820	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
RAM_RS03840	COG1215	transferase activity, transferring glycosyl groups
RAM_RS03850	COG2226	methyltransferase
RAM_RS03860	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
RAM_RS03865	COG0798	PFAM Bile acid sodium symporter
RAM_RS03870	COG0640	Transcriptional regulator
RAM_RS03880	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
RAM_RS03885	COG0459	protein refolding
RAM_RS03935	COG0516	GMP reductase activity
RAM_RS03955	COG0277	FAD linked oxidase domain protein
RAM_RS03960	COG1012	belongs to the aldehyde dehydrogenase family
RAM_RS03980	COG0518	GMP synthase (glutamine-hydrolyzing) activity
RAM_RS03980	COG0519	Catalyzes the synthesis of GMP from XMP
RAM_RS03995	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS04015	COG0697	spore germination
RAM_RS04020	COG0583	DNA-binding transcription factor activity
RAM_RS04030	COG2815	serine threonine protein kinase
RAM_RS04030	COG0515	serine threonine protein kinase
RAM_RS04080	COG0045	succinate-CoA ligase (ADP-forming) activity
RAM_RS04105	COG0138	bifunctional purine biosynthesis protein purh
RAM_RS04145	COG0587	DNA-directed DNA polymerase activity
RAM_RS04165	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
RAM_RS04175	COG2814	Major facilitator Superfamily
RAM_RS04180	COG0640	Transcriptional regulator
RAM_RS04185	COG2814	Major facilitator Superfamily
RAM_RS04195	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RAM_RS04220	COG2226	methyltransferase
RAM_RS04255	COG1234	tRNA 3'-trailer cleavage
RAM_RS04270	COG0180	Tryptophanyl-tRNA synthetase
RAM_RS04280	COG1295	ribonuclease BN
RAM_RS04295	COG1686	Belongs to the peptidase S11 family
RAM_RS04315	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
RAM_RS04330	COG2009	succinate dehydrogenase
RAM_RS04335	COG3345	alpha-galactosidase
RAM_RS04340	COG1082	Xylose isomerase domain protein TIM barrel
RAM_RS04345	COG1744	ABC transporter substrate-binding protein PnrA-like
RAM_RS04350	COG3845	ABC transporter
RAM_RS04360	COG1079	Belongs to the binding-protein-dependent transport system permease family
RAM_RS04380	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
RAM_RS04385	COG2271	Major facilitator Superfamily
RAM_RS04405	COG1733	regulation of RNA biosynthetic process
RAM_RS04415	COG1063	alcohol dehydrogenase
RAM_RS04430	COG0395	ABC-type sugar transport system, permease component
RAM_RS04465	COG1012	belongs to the aldehyde dehydrogenase family
RAM_RS04470	COG1012	belongs to the aldehyde dehydrogenase family
RAM_RS04475	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
RAM_RS04515	COG0789	Transcriptional regulator
RAM_RS04520	COG0667	Aldo Keto reductase
RAM_RS04540	COG0475	glutathione-regulated potassium exporter activity
RAM_RS04545	COG0745	RESPONSE REGULATOR receiver
RAM_RS04550	COG2205	protein histidine kinase activity
RAM_RS04570	COG0402	S-adenosylhomocysteine deaminase activity
RAM_RS04595	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
RAM_RS04625	COG0515	serine threonine protein kinase
RAM_RS04650	COG1473	amidohydrolase
RAM_RS04650	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
RAM_RS04690	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
RAM_RS04695	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
RAM_RS04700	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
RAM_RS04735	COG4770	biotin carboxylase activity
RAM_RS04750	COG1301	dicarboxylic acid transport
RAM_RS04755	COG0424	maF-like protein
RAM_RS04760	COG1472	Belongs to the glycosyl hydrolase 3 family
RAM_RS04780	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RAM_RS04785	COG1846	Transcriptional regulator
RAM_RS04795	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
RAM_RS04810	COG4585	Histidine kinase
RAM_RS04830	COG1309	transcriptional regulator
RAM_RS04840	COG1733	regulation of RNA biosynthetic process
RAM_RS04850	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS04865	COG0583	DNA-binding transcription factor activity
RAM_RS04880	COG2226	methyltransferase
RAM_RS04895	COG1902	pentaerythritol trinitrate reductase activity
RAM_RS04895	COG0446	pyridine nucleotide-disulphide oxidoreductase
RAM_RS04915	COG4585	Histidine kinase
RAM_RS04920	COG2197	response regulator
RAM_RS04925	COG3103	Sh3 type 3 domain protein
RAM_RS04925	COG0791	NLP P60 protein
RAM_RS04925	COG1388	LysM domain
RAM_RS04940	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RAM_RS04955	COG3537	Alpha-1,2-mannosidase
RAM_RS04960	COG0483	inositol monophosphate 1-phosphatase activity
RAM_RS04970	COG2205	protein histidine kinase activity
RAM_RS04975	COG2197	response regulator
RAM_RS04980	COG2197	response regulator
RAM_RS05045	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_RS05085	COG0702	epimerase
RAM_RS05090	COG1316	TRANSCRIPTIONal
RAM_RS05095	COG1316	TRANSCRIPTIONal
RAM_RS05125	COG0438	transferase activity, transferring glycosyl groups
RAM_RS05160	COG1725	Transcriptional regulator
RAM_RS05175	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
RAM_RS05175	COG0778	Nitroreductase
RAM_RS05180	COG0391	Required for morphogenesis under gluconeogenic growth conditions
RAM_RS05270	COG1611	Belongs to the LOG family
RAM_RS05285	COG1216	Glycosyl transferase, family 2
RAM_RS05310	COG0463	Glycosyl transferase, family 2
RAM_RS05315	COG1132	(ABC) transporter
RAM_RS05320	COG4988	ABC transporter
RAM_RS05325	COG1294	oxidase, subunit
RAM_RS05330	COG1271	oxidase subunit
RAM_RS05355	COG2818	Glycosylase
RAM_RS05360	COG1024	Enoyl-CoA hydratase
RAM_RS05370	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
RAM_RS05375	COG0583	DNA-binding transcription factor activity
RAM_RS05380	COG2814	Major facilitator Superfamily
RAM_RS05385	COG4122	O-methyltransferase activity
RAM_RS05390	COG1595	DNA-templated transcription, initiation
RAM_RS05400	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RAM_RS05405	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
RAM_RS05420	COG2239	Acts as a magnesium transporter
RAM_RS05430	COG0330	HflC and HflK could
RAM_RS05485	COG1309	transcriptional regulator
RAM_RS05495	COG2197	response regulator
RAM_RS05500	COG4585	Histidine kinase
RAM_RS05530	COG0598	Magnesium transport protein CorA
RAM_RS05560	COG0613	PHP domain protein
RAM_RS05565	COG2095	MarC family integral membrane protein
RAM_RS05590	COG0513	Belongs to the DEAD box helicase family
RAM_RS05620	COG2267	carboxylic ester hydrolase activity
RAM_RS05625	COG1309	transcriptional regulator
RAM_RS05630	COG2267	carboxylic ester hydrolase activity
RAM_RS05650	COG0243	molybdopterin cofactor binding
RAM_RS05655	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RAM_RS05665	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RAM_RS05665	COG2146	nitrite reductase [NAD(P)H] activity
RAM_RS05670	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RAM_RS05670	COG2146	nitrite reductase [NAD(P)H] activity
RAM_RS05695	COG2378	regulation of single-species biofilm formation
RAM_RS05755	COG0714	Associated with various cellular activities
RAM_RS05780	COG2321	neutral zinc metallopeptidase
RAM_RS05800	COG0612	Peptidase, M16
RAM_RS05820	COG1175	transmembrane transport
RAM_RS05825	COG0395	ABC-type sugar transport system, permease component
RAM_RS05830	COG1486	melibiose metabolic process
RAM_RS05845	COG0640	Transcriptional regulator
RAM_RS05860	COG3265	gluconokinase activity
RAM_RS05870	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
RAM_RS05905	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
RAM_RS05925	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
RAM_RS06015	COG1012	belongs to the aldehyde dehydrogenase family
RAM_RS06045	COG1012	belongs to the aldehyde dehydrogenase family
RAM_RS06050	COG3842	ATPase activity
RAM_RS06055	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
RAM_RS06060	COG1176	ABC-type spermidine putrescine transport system, permease component I
RAM_RS06065	COG1177	transmembrane transport
RAM_RS06070	COG0596	Alpha beta hydrolase
RAM_RS06075	COG1968	undecaprenyl-diphosphatase activity
RAM_RS06085	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
RAM_RS06090	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
RAM_RS06090	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
RAM_RS06100	COG2318	DinB family
RAM_RS06115	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
RAM_RS06115	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RAM_RS06120	COG0653	protein targeting
RAM_RS06140	COG0174	glutamine synthetase
RAM_RS06145	COG0154	amidase activity
RAM_RS06165	COG1522	sequence-specific DNA binding
RAM_RS06175	COG0518	GMP synthase (glutamine-hydrolyzing) activity
RAM_RS06175	COG0519	Catalyzes the synthesis of GMP from XMP
RAM_RS06185	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
RAM_RS06195	COG0174	glutamine synthetase
RAM_RS06255	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
RAM_RS06275	COG3480	Lon protease (S16) C-terminal proteolytic domain
RAM_RS06285	COG1615	UPF0182 protein
RAM_RS06315	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
RAM_RS06320	COG2884	Cell division ATP-binding protein ftsE
RAM_RS06325	COG2177	Part of the ABC transporter FtsEX involved in
RAM_RS06330	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
RAM_RS06355	COG2197	response regulator
RAM_RS06360	COG4585	Histidine kinase
RAM_RS06370	COG3706	GGDEF domain
RAM_RS06385	COG2986	histidine ammonia-lyase
RAM_RS06390	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
RAM_RS06400	COG0402	S-adenosylhomocysteine deaminase activity
RAM_RS06405	COG1228	amidohydrolase
RAM_RS06410	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RAM_RS06445	COG4585	Histidine kinase
RAM_RS06475	COG1131	(ABC) transporter
RAM_RS06480	COG1643	Atp-dependent helicase
RAM_RS06485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RAM_RS06505	COG3883	PFAM NLP P60 protein
RAM_RS06505	COG0791	NLP P60 protein
RAM_RS06520	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RAM_RS06530	COG2318	DinB family
RAM_RS06535	COG1472	Belongs to the glycosyl hydrolase 3 family
RAM_RS06545	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
RAM_RS06550	COG0187	DNA topoisomerase II activity
RAM_RS06595	COG1172	Belongs to the binding-protein-dependent transport system permease family
RAM_RS06600	COG1172	Belongs to the binding-protein-dependent transport system permease family
RAM_RS06605	COG1129	ABC transporter
RAM_RS06610	COG1879	ABC-type sugar transport system periplasmic component
RAM_RS06615	COG1609	Transcriptional regulator
RAM_RS06620	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
RAM_RS06630	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS06650	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
RAM_RS06680	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
RAM_RS06710	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS06720	COG0017	Asparaginyl-tRNA synthetase
RAM_RS06740	COG0596	Alpha beta hydrolase
RAM_RS06765	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RAM_RS06770	COG1486	melibiose metabolic process
RAM_RS06780	COG1053	succinate dehydrogenase
RAM_RS06785	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RAM_RS06790	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
RAM_RS06800	COG0596	Alpha beta hydrolase
RAM_RS06890	COG0697	spore germination
RAM_RS06895	COG1846	Transcriptional regulator
RAM_RS06930	COG3903	Transcriptional regulator
RAM_RS06930	COG3629	intracellular signal transduction
RAM_RS06940	COG2211	Major facilitator Superfamily
RAM_RS06950	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RAM_RS06955	COG0411	ABC transporter
RAM_RS06980	COG1309	transcriptional regulator
RAM_RS07010	COG1136	(ABC) transporter
RAM_RS07070	COG0477	Major facilitator Superfamily
RAM_RS07085	COG3387	PFAM Glycoside hydrolase 15-related
RAM_RS07090	COG1063	alcohol dehydrogenase
RAM_RS07110	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RAM_RS07160	COG3209	COG3209 Rhs family protein
RAM_RS07195	COG0604	alcohol dehydrogenase
RAM_RS07195	COG3321	synthase
RAM_RS07195	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS07225	COG2018	Roadblock/LC7 domain
RAM_RS07250	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS07255	COG0583	DNA-binding transcription factor activity
RAM_RS07260	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS07305	COG0667	Aldo Keto reductase
RAM_RS07315	COG1595	DNA-templated transcription, initiation
RAM_RS07345	COG3903	Transcriptional regulator
RAM_RS07345	COG3629	intracellular signal transduction
RAM_RS07355	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
RAM_RS07370	COG0604	alcohol dehydrogenase
RAM_RS07385	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RAM_RS07390	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_RS07435	COG1234	tRNA 3'-trailer cleavage
RAM_RS07445	COG3852	Histidine kinase
RAM_RS07450	COG2272	Belongs to the type-B carboxylesterase lipase family
RAM_RS07490	COG3547	Transposase (IS116 IS110 IS902 family)
RAM_RS07500	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
RAM_RS07580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RAM_RS07585	COG0765	amino acid transport
RAM_RS07590	COG1126	abc transporter atp-binding protein
RAM_RS07595	COG2964	Protein conserved in bacteria
RAM_RS07615	COG1131	(ABC) transporter
RAM_RS07645	COG2186	Transcriptional regulator
RAM_RS07650	COG1172	Belongs to the binding-protein-dependent transport system permease family
RAM_RS07655	COG1129	ABC transporter
RAM_RS07675	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RAM_RS07675	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RAM_RS07680	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RAM_RS07695	COG1879	ABC-type sugar transport system periplasmic component
RAM_RS07725	COG3540	Alkaline phosphatase
RAM_RS07735	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
RAM_RS07745	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
RAM_RS07750	COG1940	carbohydrate kinase activity
RAM_RS07770	COG4221	oxidoreductase activity
RAM_RS07775	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
RAM_RS07795	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RAM_RS07810	COG0513	Belongs to the DEAD box helicase family
RAM_RS07835	COG2183	response to ionizing radiation
RAM_RS07880	COG1309	transcriptional regulator
RAM_RS07895	COG2030	dehydratase
RAM_RS07895	COG1012	belongs to the aldehyde dehydrogenase family
RAM_RS07900	COG3396	Phenylacetate-CoA oxygenase
RAM_RS07905	COG3460	Phenylacetate-CoA oxygenase
RAM_RS07910	COG3396	Phenylacetate-CoA oxygenase
RAM_RS07915	COG2151	metal-sulfur cluster biosynthetic enzyme
RAM_RS07920	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RAM_RS07935	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
RAM_RS07950	COG0604	alcohol dehydrogenase
RAM_RS07965	COG0346	lactoylglutathione lyase activity
RAM_RS07970	COG0183	Belongs to the thiolase family
RAM_RS07985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RAM_RS07990	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RAM_RS07995	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
RAM_RS08000	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RAM_RS08010	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RAM_RS08020	COG3279	Response regulator of the LytR AlgR family
RAM_RS08025	COG3275	phosphorelay sensor kinase activity
RAM_RS08035	COG1879	ABC-type sugar transport system periplasmic component
RAM_RS08040	COG1172	Belongs to the binding-protein-dependent transport system permease family
RAM_RS08055	COG1609	Transcriptional regulator
RAM_RS08060	COG3537	Alpha-1,2-mannosidase
RAM_RS08065	COG3537	Alpha-1,2-mannosidase
RAM_RS08075	COG1846	Transcriptional regulator
RAM_RS08100	COG0058	SHG alpha-glucan phosphorylase activity
RAM_RS08125	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RAM_RS08140	COG1119	ATPase activity
RAM_RS08145	COG1024	Enoyl-CoA hydratase
RAM_RS08150	COG2226	methyltransferase
RAM_RS08170	COG3979	chitinase
RAM_RS08180	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RAM_RS08215	COG0667	Aldo Keto reductase
RAM_RS08220	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RAM_RS08225	COG0791	NLP P60 protein
RAM_RS08225	COG3883	PFAM NLP P60 protein
RAM_RS08230	COG1957	nucleoside hydrolase
RAM_RS08235	COG0110	maltose O-acetyltransferase activity
RAM_RS08275	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
RAM_RS08310	COG3250	beta-galactosidase activity
RAM_RS08315	COG0386	Belongs to the glutathione peroxidase family
RAM_RS08325	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
RAM_RS08335	COG1307	EDD domain protein, DegV family
RAM_RS08345	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
RAM_RS08360	COG0604	alcohol dehydrogenase
RAM_RS08365	COG2197	response regulator
RAM_RS08380	COG0482	sulfurtransferase activity
RAM_RS08400	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RAM_RS08420	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
RAM_RS08435	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
RAM_RS08440	COG0154	amidase activity
RAM_RS08445	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
RAM_RS08470	COG0673	inositol 2-dehydrogenase activity
RAM_RS08480	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
RAM_RS08490	COG0129	dihydroxy-acid dehydratase activity
RAM_RS08505	COG0440	acetolactate synthase activity
RAM_RS08510	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
RAM_RS08550	COG1404	Belongs to the peptidase S8 family
RAM_RS08555	COG0473	3-isopropylmalate dehydrogenase activity
RAM_RS08560	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RAM_RS08565	COG0179	Fumarylacetoacetate (FAA) hydrolase
RAM_RS08595	COG3629	intracellular signal transduction
RAM_RS08595	COG3903	Transcriptional regulator
RAM_RS08650	COG0776	regulation of translation
RAM_RS08660	COG0420	3'-5' exonuclease activity
RAM_RS08665	COG0419	ATPase involved in DNA repair
RAM_RS08675	COG1472	Belongs to the glycosyl hydrolase 3 family
RAM_RS08700	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
RAM_RS08705	COG0066	3-isopropylmalate dehydratase activity
RAM_RS08715	COG3903	Transcriptional regulator
RAM_RS08715	COG3629	intracellular signal transduction
RAM_RS08730	COG1920	GTP binding
RAM_RS08740	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
RAM_RS08750	COG0252	asparaginase activity
RAM_RS08760	COG1477	protein flavinylation
RAM_RS08775	COG0745	RESPONSE REGULATOR receiver
RAM_RS08780	COG2205	protein histidine kinase activity
RAM_RS08790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RAM_RS08820	COG3345	alpha-galactosidase
RAM_RS08825	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
RAM_RS08830	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
RAM_RS08840	COG0227	Belongs to the bacterial ribosomal protein bL28 family
RAM_RS08845	COG1461	Dihydroxyacetone kinase
RAM_RS08875	COG1404	Belongs to the peptidase S8 family
RAM_RS08880	COG5433	transposase activity
RAM_RS08960	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
RAM_RS08985	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
RAM_RS08995	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RAM_RS09000	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RAM_RS09010	COG0542	response to heat
RAM_RS09015	COG4249	Peptidase C14 caspase catalytic subunit p20
RAM_RS09015	COG2319	Wd-40 repeat
RAM_RS09020	COG3973	AAA domain
RAM_RS09025	COG0742	ribosomal rna small subunit methyltransferase
RAM_RS09030	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
RAM_RS09060	COG0333	Belongs to the bacterial ribosomal protein bL32 family
RAM_RS09065	COG0571	ribonuclease III activity
RAM_RS09075	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
RAM_RS09095	COG3386	PFAM SMP-30 Gluconolaconase
RAM_RS09125	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
RAM_RS09130	COG1012	belongs to the aldehyde dehydrogenase family
RAM_RS09150	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
RAM_RS09150	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
RAM_RS09155	COG0404	The glycine cleavage system catalyzes the degradation of glycine
RAM_RS09160	COG0509	glycine decarboxylation via glycine cleavage system
RAM_RS09165	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
RAM_RS09170	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
RAM_RS09175	COG1760	l-serine dehydratase
RAM_RS09185	COG2442	InterPro IPR007367
RAM_RS09195	COG2186	Transcriptional regulator
RAM_RS09205	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RAM_RS09210	COG4122	O-methyltransferase activity
RAM_RS09215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RAM_RS09245	COG0789	Transcriptional regulator
RAM_RS09255	COG2814	Major facilitator Superfamily
RAM_RS09260	COG0179	Fumarylacetoacetate (FAA) hydrolase
RAM_RS09265	COG4948	Mandelate Racemase Muconate Lactonizing
RAM_RS09270	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS09275	COG1879	ABC-type sugar transport system periplasmic component
RAM_RS09280	COG1129	ABC transporter
RAM_RS09285	COG1172	Belongs to the binding-protein-dependent transport system permease family
RAM_RS09290	COG2186	Transcriptional regulator
RAM_RS09335	COG1929	Belongs to the glycerate kinase type-1 family
RAM_RS09340	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
RAM_RS09350	COG1940	carbohydrate kinase activity
RAM_RS09355	COG1653	transport
RAM_RS09365	COG0395	ABC-type sugar transport system, permease component
RAM_RS09370	COG3345	alpha-galactosidase
RAM_RS09375	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
RAM_RS09380	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
RAM_RS09385	COG0183	Belongs to the thiolase family
RAM_RS09390	COG3485	protocatechuate 3,4-dioxygenase
RAM_RS09395	COG3485	protocatechuate 3,4-dioxygenase
RAM_RS09400	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
RAM_RS09410	COG1414	Transcriptional regulator
RAM_RS09415	COG0746	molybdenum cofactor guanylyltransferase activity
RAM_RS09420	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
RAM_RS09460	COG3706	GGDEF domain
RAM_RS09470	COG0667	Aldo Keto reductase
RAM_RS09495	COG3962	Belongs to the TPP enzyme family
RAM_RS09500	COG3718	enzyme involved in inositol metabolism
RAM_RS09510	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RAM_RS09530	COG1082	Xylose isomerase domain protein TIM barrel
RAM_RS09535	COG1609	Transcriptional regulator
RAM_RS09540	COG0673	inositol 2-dehydrogenase activity
RAM_RS09545	COG0367	asparagine synthase
RAM_RS09555	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
RAM_RS09560	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
RAM_RS09565	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
RAM_RS09600	COG1254	Belongs to the acylphosphatase family
RAM_RS09615	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RAM_RS09620	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
RAM_RS09640	COG1414	Transcriptional regulator
RAM_RS09645	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
RAM_RS09680	COG3835	regulator
RAM_RS09700	COG1529	Aldehyde oxidase and xanthine dehydrogenase
RAM_RS09705	COG3345	alpha-galactosidase
RAM_RS09710	COG1309	transcriptional regulator
RAM_RS09740	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
RAM_RS09745	COG4266	Belongs to the allantoicase family
RAM_RS09750	COG1832	CoA-binding protein
RAM_RS09755	COG2873	o-acetylhomoserine
RAM_RS09775	COG1595	DNA-templated transcription, initiation
RAM_RS09800	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
RAM_RS09820	COG3706	GGDEF domain
RAM_RS09825	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS09830	COG1309	transcriptional regulator
RAM_RS09840	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
RAM_RS09850	COG1132	(ABC) transporter
RAM_RS09875	COG0228	four-way junction DNA binding
RAM_RS09895	COG0336	Belongs to the RNA methyltransferase TrmD family
RAM_RS09900	COG0335	large ribosomal subunit rRNA binding
RAM_RS09905	COG0681	Belongs to the peptidase S26 family
RAM_RS09910	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
RAM_RS09920	COG0792	nuclease activity
RAM_RS09945	COG1191	sigma factor activity
RAM_RS09955	COG0052	Belongs to the universal ribosomal protein uS2 family
RAM_RS09960	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
RAM_RS09965	COG0528	UMP kinase activity
RAM_RS09970	COG0233	cytoplasmic translational termination
RAM_RS09990	COG1695	Transcriptional regulator
RAM_RS09995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RAM_RS10005	COG1120	ATPase activity
RAM_RS10010	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RAM_RS10015	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
RAM_RS10025	COG0820	rRNA (adenine-C2-)-methyltransferase activity
RAM_RS10075	COG0402	S-adenosylhomocysteine deaminase activity
RAM_RS10090	COG0402	S-adenosylhomocysteine deaminase activity
RAM_RS10130	COG0789	Transcriptional regulator
RAM_RS10150	COG3795	YCII-related domain
RAM_RS10155	COG0702	epimerase
RAM_RS10170	COG1476	TRANSCRIPTIONal
RAM_RS10180	COG3795	YCII-related domain
RAM_RS10185	COG4941	Belongs to the sigma-70 factor family
RAM_RS10205	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
RAM_RS10215	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS10230	COG0596	Alpha beta hydrolase
RAM_RS10240	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
RAM_RS10250	COG2814	Major facilitator Superfamily
RAM_RS10255	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
RAM_RS10265	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
RAM_RS10270	COG0750	zinc metalloprotease
RAM_RS10275	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
RAM_RS10305	COG0454	-acetyltransferase
RAM_RS10305	COG0456	acetyltransferase
RAM_RS10340	COG2186	Transcriptional regulator
RAM_RS10375	COG0513	Belongs to the DEAD box helicase family
RAM_RS10410	COG0583	DNA-binding transcription factor activity
RAM_RS10420	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RAM_RS10425	COG3022	response to hydroperoxide
RAM_RS10460	COG0442	prolyl-tRNA aminoacylation
RAM_RS10475	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
RAM_RS10530	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RAM_RS10530	COG1017	nitric oxide dioxygenase activity
RAM_RS10545	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
RAM_RS10565	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RAM_RS10595	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
RAM_RS10615	COG4152	abc transporter atp-binding protein
RAM_RS10620	COG1668	transmembrane transport
RAM_RS10630	COG3201	nicotinamide mononucleotide transporter
RAM_RS10635	COG1620	l-lactate permease
RAM_RS10645	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS10655	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
RAM_RS10780	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
RAM_RS10810	COG0477	Major facilitator Superfamily
RAM_RS10830	COG1960	acyl-CoA dehydrogenase activity
RAM_RS10840	COG1104	cysteine desulfurase activity
RAM_RS10850	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
RAM_RS10870	COG1113	amino acid transport
RAM_RS10875	COG2186	Transcriptional regulator
RAM_RS10880	COG0587	DNA-directed DNA polymerase activity
RAM_RS10885	COG0477	Major facilitator Superfamily
RAM_RS10910	COG1376	ErfK ybiS ycfS ynhG family protein
RAM_RS10920	COG0586	Pfam SNARE associated Golgi protein
RAM_RS10925	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
RAM_RS10940	COG1309	transcriptional regulator
RAM_RS10950	COG0321	lipoyl(octanoyl) transferase activity
RAM_RS10960	COG1090	epimerase
RAM_RS10970	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RAM_RS11020	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
RAM_RS11030	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
RAM_RS11030	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
RAM_RS11045	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
RAM_RS11050	COG0667	Aldo Keto reductase
RAM_RS11070	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RAM_RS11080	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
RAM_RS11115	COG1845	cytochrome c oxidase, subunit III
RAM_RS11120	COG2010	Cytochrome c
RAM_RS11130	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
RAM_RS11165	COG0438	transferase activity, transferring glycosyl groups
RAM_RS11180	COG2124	cytochrome p450
RAM_RS11185	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RAM_RS11190	COG0659	secondary active sulfate transmembrane transporter activity
RAM_RS11195	COG0659	secondary active sulfate transmembrane transporter activity
RAM_RS11200	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
RAM_RS11220	COG0501	Belongs to the peptidase M48B family
RAM_RS11225	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
RAM_RS11235	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
RAM_RS11240	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
RAM_RS11245	COG0157	Belongs to the NadC ModD family
RAM_RS11250	COG1404	Belongs to the peptidase S8 family
RAM_RS11290	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_RS11310	COG1674	ftsk spoiiie
RAM_RS11335	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
RAM_RS11345	COG5520	Belongs to the glycosyl hydrolase 30 family
RAM_RS11360	COG4566	intracellular signal transduction
RAM_RS11365	COG2197	response regulator
RAM_RS11375	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
RAM_RS11385	COG0131	Imidazoleglycerol-phosphate dehydratase
RAM_RS11400	COG2267	carboxylic ester hydrolase activity
RAM_RS11405	COG2409	Drug exporters of the RND superfamily
RAM_RS11410	COG1309	transcriptional regulator
RAM_RS11415	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
RAM_RS11425	COG3959	Transketolase, thiamine diphosphate binding domain
RAM_RS11430	COG3958	Transketolase
RAM_RS11445	COG1960	acyl-CoA dehydrogenase activity
RAM_RS11455	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
RAM_RS11460	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
RAM_RS11520	COG0107	imidazoleglycerol-phosphate synthase activity
RAM_RS11530	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
RAM_RS11565	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
RAM_RS11575	COG0134	indole-3-glycerol-phosphate synthase activity
RAM_RS11580	COG0133	tryptophan synthase activity
RAM_RS11585	COG0159	tryptophan synthase activity
RAM_RS11590	COG0789	Transcriptional regulator
RAM_RS11610	COG0174	glutamine synthetase
RAM_RS11625	COG1473	amidohydrolase
RAM_RS11630	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
RAM_RS11640	COG0067	glutamate synthase
RAM_RS11640	COG0069	glutamate synthase activity
RAM_RS11640	COG0070	glutamate synthase
RAM_RS11665	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
RAM_RS11690	COG2268	Band 7 protein
RAM_RS11700	COG2815	serine threonine protein kinase
RAM_RS11700	COG0515	serine threonine protein kinase
RAM_RS11730	COG0142	geranyltranstransferase activity
RAM_RS11785	COG0242	peptide deformylase activity
RAM_RS11790	COG1201	RNA secondary structure unwinding
RAM_RS11795	COG1349	DNA-binding transcription factor activity
RAM_RS11805	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
RAM_RS11815	COG0443	Heat shock 70 kDa protein
RAM_RS11825	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
RAM_RS11830	COG2137	regulation of response to DNA damage stimulus
RAM_RS11850	COG0800	Aldolase
RAM_RS11870	COG1053	succinate dehydrogenase
RAM_RS11900	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS11905	COG0765	amino acid transport
RAM_RS11910	COG0765	amino acid transport
RAM_RS11915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RAM_RS11920	COG1126	abc transporter atp-binding protein
RAM_RS11930	COG3850	Histidine kinase
RAM_RS11930	COG0642	Histidine kinase
RAM_RS11940	COG1733	regulation of RNA biosynthetic process
RAM_RS12005	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
RAM_RS12020	COG1196	nuclear chromosome segregation
RAM_RS12025	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
RAM_RS12035	COG0525	valine-tRNA ligase activity
RAM_RS12050	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
RAM_RS12060	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
RAM_RS12070	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
RAM_RS12075	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RAM_RS12095	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
RAM_RS12105	COG1505	serine-type exopeptidase activity
RAM_RS12140	COG2936	dipeptidyl-peptidase activity
RAM_RS12145	COG1434	Gram-negative-bacterium-type cell wall biogenesis
RAM_RS12155	COG2197	response regulator
RAM_RS12160	COG4585	Histidine kinase
RAM_RS12175	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
RAM_RS12180	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
RAM_RS12195	COG0123	including yeast histone deacetylase and acetoin utilization protein
RAM_RS12210	COG1960	acyl-CoA dehydrogenase activity
RAM_RS12215	COG1960	acyl-CoA dehydrogenase activity
RAM_RS12225	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS12235	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
RAM_RS12240	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
RAM_RS12290	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RAM_RS12305	COG1609	Transcriptional regulator
RAM_RS12320	COG0395	ABC-type sugar transport system, permease component
RAM_RS12325	COG2723	6-phospho-beta-galactosidase activity
RAM_RS12350	COG0003	Pfam Anion-transporting ATPase
RAM_RS12360	COG1940	carbohydrate kinase activity
RAM_RS12375	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
RAM_RS12400	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
RAM_RS12435	COG0640	Transcriptional regulator
RAM_RS12455	COG1946	Acyl-CoA thioesterase
RAM_RS12475	COG2197	response regulator
RAM_RS12480	COG1012	belongs to the aldehyde dehydrogenase family
RAM_RS12495	COG1960	acyl-CoA dehydrogenase activity
RAM_RS12500	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RAM_RS12525	COG1566	PFAM secretion protein HlyD family protein
RAM_RS12540	COG1309	transcriptional regulator
RAM_RS12545	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RAM_RS12560	COG2018	Roadblock/LC7 domain
RAM_RS12590	COG1703	isobutyryl-CoA mutase activity
RAM_RS12590	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
RAM_RS12590	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
RAM_RS12600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RAM_RS12605	COG1309	transcriptional regulator
RAM_RS12610	COG1960	acyl-CoA dehydrogenase activity
RAM_RS12615	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
RAM_RS12625	COG0657	acetylesterase activity
RAM_RS12630	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RAM_RS12635	COG0748	coenzyme F420 binding
RAM_RS12645	COG1960	acyl-CoA dehydrogenase activity
RAM_RS12650	COG1960	acyl-CoA dehydrogenase activity
RAM_RS12655	COG2030	dehydratase
RAM_RS12675	COG0196	riboflavin kinase activity
RAM_RS12680	COG2030	dehydratase
RAM_RS12700	COG1053	succinate dehydrogenase
RAM_RS12710	COG1960	acyl-CoA dehydrogenase activity
RAM_RS12715	COG2267	carboxylic ester hydrolase activity
RAM_RS12720	COG0346	lactoylglutathione lyase activity
RAM_RS12725	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
RAM_RS12750	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
RAM_RS12770	COG0583	DNA-binding transcription factor activity
RAM_RS12780	COG0446	pyridine nucleotide-disulphide oxidoreductase
RAM_RS12830	COG1473	amidohydrolase
RAM_RS12840	COG1228	amidohydrolase
RAM_RS12845	COG0596	Alpha beta hydrolase
RAM_RS12850	COG0183	Belongs to the thiolase family
RAM_RS12855	COG2124	cytochrome p450
RAM_RS12870	COG1295	ribonuclease BN
RAM_RS12900	COG2070	2-Nitropropane dioxygenase
RAM_RS12915	COG2188	Transcriptional regulator
RAM_RS12935	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
RAM_RS12935	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
RAM_RS12945	COG1490	D-aminoacyl-tRNA deacylase activity
RAM_RS12950	COG2890	protein-(glutamine-N5) methyltransferase activity
RAM_RS12970	COG2313	pseudouridylate synthase activity
RAM_RS12995	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RAM_RS13010	COG4213	ABC transporter substrate-binding protein
RAM_RS13020	COG4214	carbohydrate transport
RAM_RS13050	COG0531	amino acid
RAM_RS13080	COG0366	Alpha amylase catalytic
RAM_RS13085	COG0366	Alpha amylase catalytic
RAM_RS13095	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
RAM_RS13110	COG1940	carbohydrate kinase activity
RAM_RS13115	COG0483	inositol monophosphate 1-phosphatase activity
RAM_RS13135	COG0756	dUTP diphosphatase activity
RAM_RS13165	COG0569	domain protein
RAM_RS13170	COG0531	amino acid
RAM_RS13175	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
RAM_RS13185	COG1012	belongs to the aldehyde dehydrogenase family
RAM_RS13190	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
RAM_RS13195	COG1609	Transcriptional regulator
RAM_RS13205	COG1012	belongs to the aldehyde dehydrogenase family
RAM_RS13210	COG0028	Belongs to the TPP enzyme family
RAM_RS13230	COG0745	RESPONSE REGULATOR receiver
RAM_RS13235	COG2205	protein histidine kinase activity
RAM_RS13240	COG0657	acetylesterase activity
RAM_RS13255	COG1024	Enoyl-CoA hydratase
RAM_RS13255	COG1250	3-hydroxyacyl-CoA dehydrogenase
RAM_RS13260	COG0183	Belongs to the thiolase family
RAM_RS13295	COG0531	amino acid
RAM_RS13310	COG2197	response regulator
RAM_RS13320	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
RAM_RS13330	COG3253	May function as heme-dependent peroxidase
RAM_RS13335	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RAM_RS13345	COG3220	belongs to the UPF0276 family
RAM_RS13360	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
RAM_RS13390	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RAM_RS13395	COG0539	negative regulation of cytoplasmic translation
RAM_RS13405	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
RAM_RS13405	COG2508	Transcriptional regulator
RAM_RS13410	COG1012	belongs to the aldehyde dehydrogenase family
RAM_RS13420	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RAM_RS13430	COG3795	YCII-related domain
RAM_RS13440	COG4941	Belongs to the sigma-70 factor family
RAM_RS13450	COG1793	dna ligase
RAM_RS13475	COG1302	Protein conserved in bacteria
RAM_RS13485	COG1595	DNA-templated transcription, initiation
RAM_RS13520	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
RAM_RS13525	COG0640	Transcriptional regulator
RAM_RS13535	COG2326	polyphosphate kinase activity
RAM_RS13550	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
RAM_RS13555	COG1993	acr, cog1993
RAM_RS13560	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
RAM_RS13590	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
RAM_RS13590	COG1672	PFAM Archaeal ATPase
RAM_RS13615	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
RAM_RS13640	COG2124	cytochrome p450
RAM_RS13660	COG2084	Dehydrogenase
RAM_RS13675	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
RAM_RS13685	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
RAM_RS13690	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
RAM_RS13695	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
RAM_RS13700	COG1309	transcriptional regulator
RAM_RS13710	COG1073	alpha beta
RAM_RS13720	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RAM_RS13730	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
RAM_RS13735	COG1263	PTS System
RAM_RS13740	COG2188	Transcriptional regulator
RAM_RS13745	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RAM_RS13750	COG2190	(PTS) system
RAM_RS13750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RAM_RS13750	COG1263	PTS System
RAM_RS13775	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
RAM_RS13780	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
RAM_RS13785	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
RAM_RS13790	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
RAM_RS13795	COG0346	lactoylglutathione lyase activity
RAM_RS13810	COG0006	proline dipeptidase activity
RAM_RS13815	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
RAM_RS13820	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
RAM_RS13840	COG0540	Belongs to the ATCase OTCase family
RAM_RS13855	COG0505	Belongs to the CarA family
RAM_RS13860	COG0419	ATPase involved in DNA repair
RAM_RS13875	COG0284	orotidine-5'-phosphate decarboxylase activity
RAM_RS13885	COG0194	GDP metabolic process
RAM_RS13890	COG1758	RNA polymerase activity
RAM_RS13900	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
RAM_RS13925	COG0405	Gamma-glutamyltransferase
RAM_RS13930	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
RAM_RS13955	COG2197	response regulator
RAM_RS13960	COG4585	Histidine kinase
RAM_RS13975	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
RAM_RS13975	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
RAM_RS13980	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
RAM_RS14000	COG0322	excinuclease ABC activity
RAM_RS14005	COG1660	Displays ATPase and GTPase activities
RAM_RS14015	COG1481	regulation of sporulation
RAM_RS14020	COG0463	Glycosyl transferase, family 2
RAM_RS14045	COG3250	beta-galactosidase activity
RAM_RS14050	COG0408	coproporphyrinogen oxidase activity
RAM_RS14090	COG1280	lysine exporter protein (LysE YggA)
RAM_RS14100	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
RAM_RS14105	COG0126	phosphoglycerate kinase activity
RAM_RS14110	COG0149	triose-phosphate isomerase activity
RAM_RS14130	COG0363	glucosamine-6-phosphate deaminase activity
RAM_RS14145	COG0166	Belongs to the GPI family
RAM_RS14150	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
RAM_RS14160	COG0109	protoheme IX farnesyltransferase activity
RAM_RS14265	COG0396	ATPase activity
RAM_RS14280	COG2151	metal-sulfur cluster biosynthetic enzyme
RAM_RS14290	COG1742	UPF0060 membrane protein
RAM_RS14300	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
RAM_RS14310	COG4585	Histidine kinase
RAM_RS14320	COG2226	methyltransferase
RAM_RS14355	COG0457	Tetratricopeptide repeat
RAM_RS14420	COG0488	(ABC) transporter
RAM_RS14445	COG1132	(ABC) transporter
RAM_RS14450	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
RAM_RS14455	COG4821	SIS domain
RAM_RS14465	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
RAM_RS14470	COG1316	TRANSCRIPTIONal
RAM_RS14475	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RAM_RS14485	COG3300	MHYT domain
RAM_RS14485	COG5001	Diguanylate cyclase
RAM_RS14500	COG1051	belongs to the nudix hydrolase family
RAM_RS14510	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
RAM_RS14510	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RAM_RS14520	COG1024	Enoyl-CoA hydratase
RAM_RS14545	COG1960	acyl-CoA dehydrogenase activity
RAM_RS14550	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
RAM_RS14565	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS14590	COG3469	chitinase activity
RAM_RS14625	COG1309	transcriptional regulator
RAM_RS14630	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
RAM_RS14640	COG3693	PFAM glycoside hydrolase, family 10
RAM_RS14670	COG1309	transcriptional regulator
RAM_RS14675	COG0789	Transcriptional regulator
RAM_RS14690	COG4249	Peptidase C14 caspase catalytic subunit p20
RAM_RS14690	COG2319	Wd-40 repeat
RAM_RS14705	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RAM_RS14770	COG2197	response regulator
RAM_RS14835	COG0300	oxidoreductase activity
RAM_RS14845	COG1846	Transcriptional regulator
RAM_RS14860	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
RAM_RS14875	COG1595	DNA-templated transcription, initiation
RAM_RS14885	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
RAM_RS14895	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
RAM_RS14900	COG1799	cell septum assembly
RAM_RS14910	COG3599	regulation of cell shape
RAM_RS14920	COG0640	Transcriptional regulator
RAM_RS14925	COG0477	Major facilitator Superfamily
RAM_RS14930	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
RAM_RS14940	COG0640	Transcriptional regulator
RAM_RS14945	COG3263	regulation of cellular component size
RAM_RS14950	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
RAM_RS14960	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
RAM_RS14985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RAM_RS14995	COG0248	Ppx GppA phosphatase
RAM_RS15040	COG1846	Transcriptional regulator
RAM_RS15040	COG1940	carbohydrate kinase activity
RAM_RS15050	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
RAM_RS15075	COG1529	Aldehyde oxidase and xanthine dehydrogenase
RAM_RS15075	COG2010	Cytochrome c
RAM_RS15100	COG1309	transcriptional regulator
RAM_RS15105	COG4221	oxidoreductase activity
RAM_RS15110	COG0667	Aldo Keto reductase
RAM_RS15115	COG0542	response to heat
RAM_RS15125	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
RAM_RS15135	COG0514	ATP-dependent DNA helicase (RecQ)
RAM_RS15145	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS15180	COG2205	protein histidine kinase activity
RAM_RS15185	COG0745	RESPONSE REGULATOR receiver
RAM_RS15195	COG0076	glutamate decarboxylase activity
RAM_RS15250	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RAM_RS15260	COG1131	(ABC) transporter
RAM_RS15280	COG0604	alcohol dehydrogenase
RAM_RS15290	COG2764	glyoxalase bleomycin resistance protein dioxygenase
RAM_RS15310	COG4585	Histidine kinase
RAM_RS15320	COG1529	Aldehyde oxidase and xanthine dehydrogenase
RAM_RS15325	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
RAM_RS15330	COG2080	2 iron, 2 sulfur cluster binding
RAM_RS15355	COG2188	Transcriptional regulator
RAM_RS15365	COG1063	alcohol dehydrogenase
RAM_RS15380	COG2172	sigma factor antagonist activity
RAM_RS15385	COG1366	Belongs to the anti-sigma-factor antagonist family
RAM_RS15390	COG1366	Belongs to the anti-sigma-factor antagonist family
RAM_RS15415	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS15420	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
RAM_RS15430	COG3546	catalase activity
RAM_RS15440	COG0702	epimerase
RAM_RS15445	COG1733	regulation of RNA biosynthetic process
RAM_RS15470	COG1609	Transcriptional regulator
RAM_RS15480	COG1175	transmembrane transport
RAM_RS15485	COG0395	ABC-type sugar transport system, permease component
RAM_RS15505	COG0667	Aldo Keto reductase
RAM_RS15515	COG0667	Aldo Keto reductase
RAM_RS15525	COG2378	regulation of single-species biofilm formation
RAM_RS15535	COG1691	(AIR) carboxylase
RAM_RS15540	COG3875	lactate racemase activity
RAM_RS15545	COG3618	amidohydrolase
RAM_RS15550	COG0179	Fumarylacetoacetate (FAA) hydrolase
RAM_RS15555	COG4948	Mandelate Racemase Muconate Lactonizing
RAM_RS15570	COG1129	ABC transporter
RAM_RS15610	COG1609	Transcriptional regulator
RAM_RS15615	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_RS15635	COG3251	PFAM MbtH domain protein
RAM_RS15655	COG2124	cytochrome p450
RAM_RS15680	COG0604	alcohol dehydrogenase
RAM_RS15695	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
RAM_RS15750	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS15770	COG3250	beta-galactosidase activity
RAM_RS15790	COG1309	transcriptional regulator
RAM_RS15795	COG0596	Alpha beta hydrolase
RAM_RS15805	COG1960	acyl-CoA dehydrogenase activity
RAM_RS15810	COG1960	acyl-CoA dehydrogenase activity
RAM_RS15835	COG4948	Mandelate Racemase Muconate Lactonizing
RAM_RS15850	COG0395	ABC-type sugar transport system, permease component
RAM_RS15855	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
RAM_RS15860	COG0515	serine threonine protein kinase
RAM_RS15895	COG2814	Major facilitator Superfamily
RAM_RS15905	COG2205	protein histidine kinase activity
RAM_RS15910	COG0745	RESPONSE REGULATOR receiver
RAM_RS15925	COG1131	(ABC) transporter
RAM_RS15945	COG1309	transcriptional regulator
RAM_RS15955	COG1136	(ABC) transporter
RAM_RS15970	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
RAM_RS15975	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RAM_RS15985	COG1595	DNA-templated transcription, initiation
RAM_RS16005	COG0596	Alpha beta hydrolase
RAM_RS16015	COG0477	Major facilitator Superfamily
RAM_RS16060	COG0366	Alpha amylase catalytic
RAM_RS16075	COG0395	ABC-type sugar transport system, permease component
RAM_RS16080	COG1175	transmembrane transport
RAM_RS16095	COG1349	DNA-binding transcription factor activity
RAM_RS16105	COG1609	Transcriptional regulator
RAM_RS16110	COG2815	serine threonine protein kinase
RAM_RS16110	COG0515	serine threonine protein kinase
RAM_RS16115	COG0515	serine threonine protein kinase
RAM_RS16115	COG2815	serine threonine protein kinase
RAM_RS16130	COG0437	4 iron, 4 sulfur cluster binding
RAM_RS16135	COG0243	molybdopterin cofactor binding
RAM_RS16135	COG3383	formate dehydrogenase (NAD+) activity
RAM_RS16140	COG0243	molybdopterin cofactor binding
RAM_RS16145	COG2271	Major facilitator Superfamily
RAM_RS16160	COG2318	DinB family
RAM_RS16190	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
RAM_RS16200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RAM_RS16205	COG0583	DNA-binding transcription factor activity
RAM_RS16215	COG1053	succinate dehydrogenase
RAM_RS16220	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
RAM_RS16255	COG3511	phospholipase C
RAM_RS16290	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RAM_RS16295	COG3938	Belongs to the proline racemase family
RAM_RS16305	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RAM_RS16305	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RAM_RS16310	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RAM_RS16320	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
RAM_RS16325	COG0395	ABC-type sugar transport system, permease component
RAM_RS16330	COG1175	transmembrane transport
RAM_RS16380	COG0628	permease
RAM_RS16385	COG3507	Belongs to the glycosyl hydrolase 43 family
RAM_RS16390	COG3285	dna ligase
RAM_RS16390	COG1793	dna ligase
RAM_RS16405	COG2226	methyltransferase
RAM_RS16445	COG1250	3-hydroxyacyl-CoA dehydrogenase
RAM_RS16450	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RAM_RS16455	COG1024	Enoyl-CoA hydratase
RAM_RS16470	COG1012	belongs to the aldehyde dehydrogenase family
RAM_RS16540	COG3507	Belongs to the glycosyl hydrolase 43 family
RAM_RS16610	COG1309	transcriptional regulator
RAM_RS16615	COG1595	DNA-templated transcription, initiation
RAM_RS16630	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS16635	COG0028	Belongs to the TPP enzyme family
RAM_RS16675	COG2188	Transcriptional regulator
RAM_RS16680	COG3525	Glycosyl hydrolase, family 20, catalytic domain
RAM_RS16685	COG0395	ABC-type sugar transport system, permease component
RAM_RS16690	COG1175	transmembrane transport
RAM_RS16695	COG2182	Extracellular solute-binding protein
RAM_RS16705	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
RAM_RS16750	COG1609	Transcriptional regulator
RAM_RS16780	COG3591	Belongs to the peptidase S1B family
RAM_RS16805	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
RAM_RS16835	COG2267	carboxylic ester hydrolase activity
RAM_RS16865	COG2357	RelA SpoT domain protein
RAM_RS16890	COG1280	lysine exporter protein (LysE YggA)
RAM_RS16895	COG0484	heat shock protein binding
RAM_RS16900	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RAM_RS16925	COG2409	Drug exporters of the RND superfamily
RAM_RS16935	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_RS16945	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
RAM_RS16985	COG1024	Enoyl-CoA hydratase
RAM_RS17005	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RAM_RS17010	COG0183	Belongs to the thiolase family
RAM_RS17020	COG1960	acyl-CoA dehydrogenase activity
RAM_RS17025	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_RS17030	COG1024	Enoyl-CoA hydratase
RAM_RS17035	COG1960	acyl-CoA dehydrogenase activity
RAM_RS17040	COG1960	acyl-CoA dehydrogenase activity
RAM_RS17045	COG1960	acyl-CoA dehydrogenase activity
RAM_RS17060	COG1802	Transcriptional regulator
RAM_RS17065	COG1864	DNA RNA non-specific endonuclease
RAM_RS17065	COG3591	Belongs to the peptidase S1B family
RAM_RS17080	COG1063	alcohol dehydrogenase
RAM_RS17085	COG2267	carboxylic ester hydrolase activity
RAM_RS17105	COG1309	transcriptional regulator
RAM_RS17110	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
RAM_RS17125	COG3345	alpha-galactosidase
RAM_RS17140	COG1175	transmembrane transport
RAM_RS17145	COG0395	ABC-type sugar transport system, permease component
RAM_RS17170	COG5640	endopeptidase activity
RAM_RS17180	COG0477	Major facilitator Superfamily
RAM_RS17190	COG1940	carbohydrate kinase activity
RAM_RS17195	COG0531	amino acid
RAM_RS17200	COG3250	beta-galactosidase activity
RAM_RS17205	COG1940	carbohydrate kinase activity
RAM_RS17215	COG1609	Transcriptional regulator
RAM_RS17230	COG2124	cytochrome p450
RAM_RS17270	COG1846	Transcriptional regulator
RAM_RS17275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RAM_RS17325	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_RS17355	COG0702	epimerase
RAM_RS17380	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
RAM_RS17395	COG4948	Mandelate Racemase Muconate Lactonizing
RAM_RS17415	COG0601	transmembrane transport
RAM_RS17420	COG0444	Belongs to the ABC transporter superfamily
RAM_RS17425	COG4608	Belongs to the ABC transporter superfamily
RAM_RS17435	COG0477	Major facilitator Superfamily
RAM_RS17470	COG0477	Major facilitator Superfamily
RAM_RS17480	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
RAM_RS17495	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RAM_RS17495	COG3321	synthase
RAM_RS17495	COG0604	alcohol dehydrogenase
RAM_RS17495	COG4221	oxidoreductase activity
RAM_RS17500	COG3507	Belongs to the glycosyl hydrolase 43 family
RAM_RS17515	COG1231	oxidoreductase activity
RAM_RS17525	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
RAM_RS17525	COG0235	Class ii aldolase
RAM_RS17540	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS17545	COG0701	Predicted permease
RAM_RS17570	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS17580	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_RS17590	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS17600	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
RAM_RS17635	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RAM_RS17665	COG0501	Belongs to the peptidase M48B family
RAM_RS17700	COG0475	glutathione-regulated potassium exporter activity
RAM_RS17700	COG0569	domain protein
RAM_RS17735	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
RAM_RS17740	COG4279	zinc finger
RAM_RS17775	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RAM_RS17805	COG0069	glutamate synthase activity
RAM_RS17810	COG0745	RESPONSE REGULATOR receiver
RAM_RS17815	COG5002	protein histidine kinase activity
RAM_RS17830	COG0577	efflux transmembrane transporter activity
RAM_RS17830	COG1136	(ABC) transporter
RAM_RS17835	COG1136	(ABC) transporter
RAM_RS17835	COG0577	efflux transmembrane transporter activity
RAM_RS17850	COG2814	Major facilitator Superfamily
RAM_RS17855	COG0596	Alpha beta hydrolase
RAM_RS17865	COG4585	Histidine kinase
RAM_RS17895	COG4585	Histidine kinase
RAM_RS17940	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
RAM_RS17985	COG0702	epimerase
RAM_RS18010	COG0745	RESPONSE REGULATOR receiver
RAM_RS18015	COG2205	protein histidine kinase activity
RAM_RS18035	COG0726	polysaccharide deacetylase
RAM_RS18085	COG0604	alcohol dehydrogenase
RAM_RS18150	COG4221	oxidoreductase activity
RAM_RS18155	COG4249	Peptidase C14 caspase catalytic subunit p20
RAM_RS18155	COG2319	Wd-40 repeat
RAM_RS18225	COG2197	response regulator
RAM_RS18230	COG0736	holo-[acyl-carrier-protein] synthase activity
RAM_RS18305	COG1834	amidinotransferase
RAM_RS18315	COG1529	Aldehyde oxidase and xanthine dehydrogenase
RAM_RS18320	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
RAM_RS18325	COG2080	2 iron, 2 sulfur cluster binding
RAM_RS18335	COG3345	alpha-galactosidase
RAM_RS18375	COG1309	transcriptional regulator
RAM_RS18405	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS18410	COG0583	DNA-binding transcription factor activity
RAM_RS18435	COG3250	beta-galactosidase activity
RAM_RS18480	COG0596	Alpha beta hydrolase
RAM_RS18485	COG0583	DNA-binding transcription factor activity
RAM_RS18575	COG2205	protein histidine kinase activity
RAM_RS18640	COG1522	sequence-specific DNA binding
RAM_RS18650	COG0604	alcohol dehydrogenase
RAM_RS18650	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RAM_RS18650	COG4221	oxidoreductase activity
RAM_RS18650	COG3321	synthase
RAM_RS18705	COG1529	Aldehyde oxidase and xanthine dehydrogenase
RAM_RS18715	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
RAM_RS18720	COG2080	2 iron, 2 sulfur cluster binding
RAM_RS18755	COG0631	protein serine/threonine phosphatase activity
RAM_RS18795	COG3509	depolymerase
RAM_RS18815	COG0601	transmembrane transport
RAM_RS18825	COG4608	Belongs to the ABC transporter superfamily
RAM_RS18835	COG1609	Transcriptional regulator
RAM_RS18840	COG4124	Belongs to the glycosyl hydrolase 26 family
RAM_RS18850	COG1846	Transcriptional regulator
RAM_RS18850	COG1940	carbohydrate kinase activity
RAM_RS18860	COG1960	acyl-CoA dehydrogenase activity
RAM_RS18865	COG2207	Transcriptional regulator
RAM_RS18935	COG0745	RESPONSE REGULATOR receiver
RAM_RS18940	COG2205	protein histidine kinase activity
RAM_RS18950	COG2755	lipolytic protein G-D-S-L family
RAM_RS18950	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
RAM_RS18965	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
RAM_RS18965	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
RAM_RS18975	COG2267	carboxylic ester hydrolase activity
RAM_RS18980	COG2226	methyltransferase
RAM_RS18990	COG0640	Transcriptional regulator
RAM_RS19025	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
RAM_RS19035	COG0375	protein maturation
RAM_RS19045	COG0409	Hydrogenase expression formation protein
RAM_RS19090	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
RAM_RS19100	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
RAM_RS19135	COG3903	Transcriptional regulator
RAM_RS19135	COG3629	intracellular signal transduction
RAM_RS19140	COG0596	Alpha beta hydrolase
RAM_RS19145	COG1024	Enoyl-CoA hydratase
RAM_RS19145	COG1250	3-hydroxyacyl-CoA dehydrogenase
RAM_RS19150	COG1733	regulation of RNA biosynthetic process
RAM_RS19175	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS19175	COG3321	synthase
RAM_RS19175	COG0604	alcohol dehydrogenase
RAM_RS19180	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS19185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RAM_RS19195	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS19225	COG0411	ABC transporter
RAM_RS19235	COG1024	Enoyl-CoA hydratase
RAM_RS19240	COG1960	acyl-CoA dehydrogenase activity
RAM_RS19245	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_RS19250	COG1946	Acyl-CoA thioesterase
RAM_RS19260	COG1024	Enoyl-CoA hydratase
RAM_RS19265	COG1960	acyl-CoA dehydrogenase activity
RAM_RS19270	COG1012	belongs to the aldehyde dehydrogenase family
RAM_RS19280	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RAM_RS19285	COG0183	Belongs to the thiolase family
RAM_RS19325	COG1946	Acyl-CoA thioesterase
RAM_RS19345	COG1960	acyl-CoA dehydrogenase activity
RAM_RS19365	COG0183	Belongs to the thiolase family
RAM_RS19380	COG0183	Belongs to the thiolase family
RAM_RS19385	COG1024	Enoyl-CoA hydratase
RAM_RS19400	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS19415	COG1024	Enoyl-CoA hydratase
RAM_RS19425	COG1960	acyl-CoA dehydrogenase activity
RAM_RS19430	COG1960	acyl-CoA dehydrogenase activity
RAM_RS19460	COG1960	acyl-CoA dehydrogenase activity
RAM_RS19475	COG1012	belongs to the aldehyde dehydrogenase family
RAM_RS19480	COG1960	acyl-CoA dehydrogenase activity
RAM_RS19485	COG1960	acyl-CoA dehydrogenase activity
RAM_RS19490	COG1024	Enoyl-CoA hydratase
RAM_RS19495	COG2188	Transcriptional regulator
RAM_RS19500	COG0300	oxidoreductase activity
RAM_RS19505	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
RAM_RS19535	COG1309	transcriptional regulator
RAM_RS19545	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
RAM_RS19550	COG3629	intracellular signal transduction
RAM_RS19550	COG3903	Transcriptional regulator
RAM_RS19570	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RAM_RS19570	COG1017	nitric oxide dioxygenase activity
RAM_RS19575	COG1846	Transcriptional regulator
RAM_RS19575	COG1940	carbohydrate kinase activity
RAM_RS19595	COG0531	amino acid
RAM_RS19600	COG3387	PFAM Glycoside hydrolase 15-related
RAM_RS19605	COG2814	Major facilitator Superfamily
RAM_RS19620	COG2197	response regulator
RAM_RS19655	COG0628	permease
RAM_RS19670	COG1486	melibiose metabolic process
RAM_RS19675	COG0395	ABC-type sugar transport system, permease component
RAM_RS19695	COG1349	DNA-binding transcription factor activity
RAM_RS19700	COG2222	sugar isomerase
RAM_RS19715	COG1105	Belongs to the carbohydrate kinase PfkB family
RAM_RS19790	COG0596	Alpha beta hydrolase
RAM_RS19800	COG1024	Enoyl-CoA hydratase
RAM_RS19800	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
RAM_RS19805	COG3629	intracellular signal transduction
RAM_RS19805	COG3903	Transcriptional regulator
RAM_RS19815	COG1132	(ABC) transporter
RAM_RS19840	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_RS19860	COG4221	oxidoreductase activity
RAM_RS19865	COG4948	Mandelate Racemase Muconate Lactonizing
RAM_RS19870	COG0395	ABC-type sugar transport system, permease component
RAM_RS19875	COG3833	ABC-type maltose transport systems, permease component
RAM_RS19910	COG2124	cytochrome p450
RAM_RS19915	COG2175	clavaminate synthase activity
RAM_RS19925	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RAM_RS19930	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS19975	COG1940	carbohydrate kinase activity
RAM_RS19980	COG1846	Transcriptional regulator
RAM_RS19980	COG1940	carbohydrate kinase activity
RAM_RS19990	COG1172	Belongs to the binding-protein-dependent transport system permease family
RAM_RS20000	COG0673	inositol 2-dehydrogenase activity
RAM_RS20010	COG0604	alcohol dehydrogenase
RAM_RS20085	COG1064	alcohol dehydrogenase
RAM_RS20090	COG1309	transcriptional regulator
RAM_RS20095	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_RS20110	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
RAM_RS20115	COG1472	Belongs to the glycosyl hydrolase 3 family
RAM_RS20135	COG2508	Transcriptional regulator
RAM_RS20140	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RAM_RS20150	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
RAM_RS20155	COG0463	Glycosyl transferase, family 2
RAM_RS20165	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_RS20175	COG3629	intracellular signal transduction
RAM_RS20180	COG0583	DNA-binding transcription factor activity
RAM_RS20190	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS20200	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS20205	COG1846	Transcriptional regulator
RAM_RS20210	COG3903	Transcriptional regulator
RAM_RS20210	COG3629	intracellular signal transduction
RAM_RS20215	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
RAM_RS20230	COG2197	response regulator
RAM_RS20240	COG0577	efflux transmembrane transporter activity
RAM_RS20240	COG1136	(ABC) transporter
RAM_RS20270	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RAM_RS20300	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RAM_RS20315	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS20325	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
RAM_RS20330	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RAM_RS20335	COG3629	intracellular signal transduction
RAM_RS20335	COG3903	Transcriptional regulator
RAM_RS20340	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
RAM_RS20360	COG3509	depolymerase
RAM_RS20365	COG2205	protein histidine kinase activity
RAM_RS20370	COG0745	RESPONSE REGULATOR receiver
RAM_RS20375	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
RAM_RS20385	COG0583	DNA-binding transcription factor activity
RAM_RS20410	COG1250	3-hydroxyacyl-CoA dehydrogenase
RAM_RS20440	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
RAM_RS20485	COG0142	geranyltranstransferase activity
RAM_RS20505	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
RAM_RS20530	COG0395	ABC-type sugar transport system, permease component
RAM_RS20550	COG1609	Transcriptional regulator
RAM_RS20580	COG0653	protein targeting
RAM_RS20605	COG1366	Belongs to the anti-sigma-factor antagonist family
RAM_RS20605	COG2172	sigma factor antagonist activity
RAM_RS20605	COG2208	phosphoserine phosphatase activity
RAM_RS20625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RAM_RS20635	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
RAM_RS20655	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
RAM_RS20660	COG1012	belongs to the aldehyde dehydrogenase family
RAM_RS20665	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RAM_RS20700	COG3661	Belongs to the glycosyl hydrolase 67 family
RAM_RS20715	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS20760	COG2201	protein-glutamate methylesterase activity
RAM_RS20765	COG2201	protein-glutamate methylesterase activity
RAM_RS20785	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
RAM_RS20830	COG0477	Major facilitator Superfamily
RAM_RS20845	COG2318	DinB family
RAM_RS20850	COG1793	dna ligase
RAM_RS20880	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
RAM_RS20890	COG2814	Major facilitator Superfamily
RAM_RS20900	COG2855	membrane
RAM_RS20910	COG0583	DNA-binding transcription factor activity
RAM_RS20940	COG0439	Biotin carboxylase
RAM_RS20980	COG0477	Major facilitator Superfamily
RAM_RS21005	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_RS21030	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
RAM_RS21050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RAM_RS21085	COG3285	dna ligase
RAM_RS21085	COG1793	dna ligase
RAM_RS21100	COG0657	acetylesterase activity
RAM_RS21115	COG2267	carboxylic ester hydrolase activity
RAM_RS21150	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
RAM_RS21165	COG3634	alkyl hydroperoxide reductase activity
RAM_RS21185	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
RAM_RS21245	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
RAM_RS21260	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
RAM_RS21270	COG2890	protein-(glutamine-N5) methyltransferase activity
RAM_RS21290	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RAM_RS21295	COG2124	cytochrome p450
RAM_RS21305	COG2201	protein-glutamate methylesterase activity
RAM_RS21320	COG0515	serine threonine protein kinase
RAM_RS21320	COG2815	serine threonine protein kinase
RAM_RS21330	COG0326	Molecular chaperone. Has ATPase activity
RAM_RS21340	COG3794	PFAM blue (type 1) copper domain protein
RAM_RS21405	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS21420	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
RAM_RS21445	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
RAM_RS21455	COG0300	oxidoreductase activity
RAM_RS21460	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
RAM_RS21460	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
RAM_RS21465	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
RAM_RS21470	COG2192	nodulation
RAM_RS21475	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
RAM_RS21490	COG0463	Glycosyl transferase, family 2
RAM_RS21490	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
RAM_RS21495	COG0297	glycogen (starch) synthase activity
RAM_RS21540	COG1959	2 iron, 2 sulfur cluster binding
RAM_RS21540	COG1295	ribonuclease BN
RAM_RS21565	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RAM_RS21565	COG0723	plastoquinol--plastocyanin reductase activity
RAM_RS21570	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
RAM_RS21575	COG2890	protein-(glutamine-N5) methyltransferase activity
RAM_RS21590	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
RAM_RS21600	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
RAM_RS21610	COG1982	Orn Lys Arg decarboxylase major
RAM_RS21630	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RAM_RS21655	COG0596	Alpha beta hydrolase
RAM_RS21680	COG3835	regulator
RAM_RS21705	COG3284	Transcriptional regulator
RAM_RS21750	COG0459	protein refolding
RAM_RS21780	COG0596	Alpha beta hydrolase
RAM_RS21785	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS21790	COG0435	Glutathione S-transferase
RAM_RS21800	COG2353	YceI-like domain
RAM_RS21805	COG1309	transcriptional regulator
RAM_RS21820	COG0395	ABC-type sugar transport system, permease component
RAM_RS21825	COG1175	transmembrane transport
RAM_RS21835	COG1609	Transcriptional regulator
RAM_RS21840	COG1472	Belongs to the glycosyl hydrolase 3 family
RAM_RS21850	COG2124	cytochrome p450
RAM_RS21860	COG5001	Diguanylate cyclase
RAM_RS21860	COG1716	ATPase activity
RAM_RS21875	COG2181	nitrate reductase activity
RAM_RS21875	COG0247	lactate metabolic process
RAM_RS21880	COG1716	ATPase activity
RAM_RS21890	COG0477	Major facilitator Superfamily
RAM_RS21900	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
RAM_RS21905	COG1082	Xylose isomerase domain protein TIM barrel
RAM_RS21905	COG3185	4-Hydroxyphenylpyruvate dioxygenase
RAM_RS21910	COG2182	Extracellular solute-binding protein
RAM_RS21915	COG1175	transmembrane transport
RAM_RS21920	COG0395	ABC-type sugar transport system, permease component
RAM_RS21925	COG1472	Belongs to the glycosyl hydrolase 3 family
RAM_RS21935	COG4991	sh3 domain protein
RAM_RS22010	COG0302	gtp cyclohydrolase
RAM_RS22025	COG1609	Transcriptional regulator
RAM_RS22045	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS22060	COG1686	Belongs to the peptidase S11 family
RAM_RS22070	COG1609	Transcriptional regulator
RAM_RS22075	COG1879	ABC-type sugar transport system periplasmic component
RAM_RS22085	COG1172	Belongs to the binding-protein-dependent transport system permease family
RAM_RS22090	COG1172	Belongs to the binding-protein-dependent transport system permease family
RAM_RS22110	COG2160	L-arabinose isomerase activity
RAM_RS22120	COG1129	ABC transporter
RAM_RS22125	COG4214	carbohydrate transport
RAM_RS22135	COG1609	Transcriptional regulator
RAM_RS22145	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
RAM_RS22150	COG1414	Transcriptional regulator
RAM_RS22160	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
RAM_RS22165	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
RAM_RS22175	COG0137	argininosuccinate synthase activity
RAM_RS22220	COG0277	FAD linked oxidase domain protein
RAM_RS22225	COG1609	Transcriptional regulator
RAM_RS22235	COG1653	transport
RAM_RS22240	COG1175	transmembrane transport
RAM_RS22245	COG0395	ABC-type sugar transport system, permease component
RAM_RS22255	COG0673	inositol 2-dehydrogenase activity
RAM_RS22260	COG0673	inositol 2-dehydrogenase activity
RAM_RS22270	COG3866	Pectate lyase
RAM_RS22300	COG3903	Transcriptional regulator
RAM_RS22300	COG3629	intracellular signal transduction
RAM_RS22315	COG0589	response to stress
RAM_RS22320	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
RAM_RS22380	COG1090	epimerase
RAM_RS22405	COG0297	glycogen (starch) synthase activity
RAM_RS22430	COG3250	beta-galactosidase activity
RAM_RS22445	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
RAM_RS22490	COG0477	Major facilitator Superfamily
RAM_RS22495	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RAM_RS22495	COG3321	synthase
RAM_RS22495	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
RAM_RS22500	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_RS22515	COG0300	oxidoreductase activity
RAM_RS22520	COG1819	glycosyl
RAM_RS22530	COG1793	dna ligase
RAM_RS22530	COG3285	dna ligase
RAM_RS22540	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
RAM_RS22555	COG2267	carboxylic ester hydrolase activity
RAM_RS22570	COG3903	Transcriptional regulator
RAM_RS22570	COG3629	intracellular signal transduction
RAM_RS22575	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
RAM_RS22585	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
RAM_RS22585	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RAM_RS22585	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
RAM_RS22600	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
RAM_RS22620	COG1472	Belongs to the glycosyl hydrolase 3 family
RAM_RS22625	COG1609	Transcriptional regulator
RAM_RS22640	COG0395	ABC-type sugar transport system, permease component
RAM_RS22650	COG1609	Transcriptional regulator
RAM_RS22670	COG1278	Cold shock
RAM_RS22675	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
RAM_RS22725	COG0387	Pfam Sodium calcium exchanger
RAM_RS22730	COG0583	DNA-binding transcription factor activity
RAM_RS22735	COG0028	Belongs to the TPP enzyme family
RAM_RS22780	COG1609	Transcriptional regulator
RAM_RS22785	COG1129	ABC transporter
RAM_RS22790	COG1172	Belongs to the binding-protein-dependent transport system permease family
RAM_RS22795	COG1172	Belongs to the binding-protein-dependent transport system permease family
RAM_RS22805	COG3254	rhamnose metabolic process
RAM_RS22815	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS22815	COG3347	Dehydrogenase
RAM_RS22825	COG1070	Carbohydrate kinase
RAM_RS22830	COG2197	response regulator
RAM_RS22835	COG4585	Histidine kinase
RAM_RS22850	COG3250	beta-galactosidase activity
RAM_RS22905	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
RAM_RS22910	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
RAM_RS22925	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
RAM_RS22940	COG0045	succinate-CoA ligase (ADP-forming) activity
RAM_RS22950	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RAM_RS22960	COG2223	nitrite transmembrane transporter activity
RAM_RS22965	COG1802	Transcriptional regulator
RAM_RS22970	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
RAM_RS22975	COG3383	formate dehydrogenase (NAD+) activity
RAM_RS22980	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
RAM_RS22985	COG1034	ATP synthesis coupled electron transport
RAM_RS22990	COG3622	Belongs to the hyi family
RAM_RS22995	COG2084	Dehydrogenase
RAM_RS23000	COG3960	tartronate-semialdehyde synthase activity
RAM_RS23015	COG1529	Aldehyde oxidase and xanthine dehydrogenase
RAM_RS23020	COG0590	tRNA wobble adenosine to inosine editing
RAM_RS23025	COG2252	PERMEase
RAM_RS23035	COG1929	Belongs to the glycerate kinase type-1 family
RAM_RS23090	COG2066	Belongs to the glutaminase family
RAM_RS23105	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
RAM_RS23120	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RAM_RS23125	COG0596	Alpha beta hydrolase
RAM_RS23135	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS23150	COG3285	dna ligase
RAM_RS23150	COG1793	dna ligase
RAM_RS23155	COG0183	Belongs to the thiolase family
RAM_RS23200	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RAM_RS23205	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RAM_RS23210	COG1609	Transcriptional regulator
RAM_RS23220	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RAM_RS23225	COG2267	carboxylic ester hydrolase activity
RAM_RS23260	COG0667	Aldo Keto reductase
RAM_RS23265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RAM_RS23270	COG1968	undecaprenyl-diphosphatase activity
RAM_RS23280	COG0339	signal peptide processing
RAM_RS23285	COG0740	serine-type endopeptidase activity
RAM_RS23290	COG0039	L-malate dehydrogenase activity
RAM_RS23325	COG3537	Alpha-1,2-mannosidase
RAM_RS23365	COG0747	negative chemotaxis
RAM_RS23370	COG0601	transmembrane transport
RAM_RS23375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RAM_RS23380	COG4172	Belongs to the ABC transporter superfamily
RAM_RS23395	COG1619	proteins homologs of microcin C7 resistance protein MccF
RAM_RS23400	COG0823	Involved in the tonB-independent uptake of proteins
RAM_RS23400	COG1506	peptidase
RAM_RS23400	COG4946	Tricorn protease homolog
RAM_RS23460	COG0477	Major facilitator Superfamily
RAM_RS23480	COG0640	Transcriptional regulator
RAM_RS23525	COG4941	Belongs to the sigma-70 factor family
RAM_RS23590	COG4941	Belongs to the sigma-70 factor family
RAM_RS23600	COG2124	cytochrome p450
RAM_RS23620	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
RAM_RS23635	COG1309	transcriptional regulator
RAM_RS23645	COG1960	acyl-CoA dehydrogenase activity
RAM_RS23650	COG1309	transcriptional regulator
RAM_RS23660	COG1396	sequence-specific DNA binding
RAM_RS23675	COG0640	Transcriptional regulator
RAM_RS23685	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
RAM_RS23710	COG1435	thymidine kinase activity
RAM_RS23720	COG0494	nUDIX hydrolase
RAM_RS23730	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
RAM_RS23735	COG0463	Glycosyl transferase, family 2
RAM_RS23745	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
RAM_RS23765	COG4977	sequence-specific DNA binding
RAM_RS23770	COG1733	regulation of RNA biosynthetic process
RAM_RS23790	COG3903	Transcriptional regulator
RAM_RS23790	COG3629	intracellular signal transduction
RAM_RS23825	COG4865	methylaspartate mutase activity
RAM_RS23830	COG0017	Asparaginyl-tRNA synthetase
RAM_RS23835	COG0069	glutamate synthase activity
RAM_RS23850	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
RAM_RS23900	COG1250	3-hydroxyacyl-CoA dehydrogenase
RAM_RS23925	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RAM_RS23950	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RAM_RS24010	COG4948	Mandelate Racemase Muconate Lactonizing
RAM_RS24015	COG2186	Transcriptional regulator
RAM_RS24020	COG0395	ABC-type sugar transport system, permease component
RAM_RS24025	COG1175	transmembrane transport
RAM_RS24030	COG3293	Transposase
RAM_RS24050	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RAM_RS24060	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
RAM_RS24065	COG4865	methylaspartate mutase activity
RAM_RS24075	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RAM_RS24120	COG0789	Transcriptional regulator
RAM_RS24170	COG2124	cytochrome p450
RAM_RS24205	COG2197	response regulator
RAM_RS24210	COG2197	response regulator
RAM_RS24220	COG0823	Involved in the tonB-independent uptake of proteins
RAM_RS24325	COG0402	S-adenosylhomocysteine deaminase activity
RAM_RS24330	COG1414	Transcriptional regulator
RAM_RS24335	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RAM_RS24345	COG3485	protocatechuate 3,4-dioxygenase
RAM_RS24365	COG3979	chitinase
RAM_RS24375	COG1136	(ABC) transporter
RAM_RS24380	COG1136	(ABC) transporter
RAM_RS24395	COG4221	oxidoreductase activity
RAM_RS24400	COG0583	DNA-binding transcription factor activity
RAM_RS24410	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
RAM_RS24450	COG4552	Acetyltransferase involved in intracellular survival and related
RAM_RS24455	COG4552	Acetyltransferase involved in intracellular survival and related
RAM_RS24475	COG1597	lipid kinase activity
RAM_RS24485	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
RAM_RS24495	COG2378	regulation of single-species biofilm formation
RAM_RS24505	COG1733	regulation of RNA biosynthetic process
RAM_RS24515	COG4221	oxidoreductase activity
RAM_RS24525	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
RAM_RS24540	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
RAM_RS24545	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
RAM_RS24580	COG0640	Transcriptional regulator
RAM_RS24595	COG0697	spore germination
RAM_RS24600	COG1222	aaa ATPase
RAM_RS24625	COG1994	Peptidase M50
RAM_RS24625	COG0517	IMP dehydrogenase activity
RAM_RS24640	COG1192	Involved in chromosome partitioning
RAM_RS24645	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
RAM_RS24650	COG0140	phosphoribosyl-ATP diphosphatase activity
RAM_RS24665	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RAM_RS24690	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
RAM_RS24705	COG2814	Major facilitator Superfamily
RAM_RS24720	COG0488	(ABC) transporter
RAM_RS24725	COG0215	cysteine-tRNA ligase activity
RAM_RS24735	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
RAM_RS24745	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
RAM_RS24760	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
RAM_RS24775	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
RAM_RS24785	COG0477	Major facilitator Superfamily
RAM_RS24790	COG0745	RESPONSE REGULATOR receiver
RAM_RS24795	COG2205	protein histidine kinase activity
RAM_RS24810	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
RAM_RS24820	COG2304	oxidoreductase activity
RAM_RS24830	COG0714	Associated with various cellular activities
RAM_RS24835	COG0746	molybdenum cofactor guanylyltransferase activity
RAM_RS24840	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
RAM_RS24845	COG0791	NLP P60 protein
RAM_RS24845	COG3883	PFAM NLP P60 protein
RAM_RS24850	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
RAM_RS24855	COG1285	pathogenesis
RAM_RS24865	COG1309	transcriptional regulator
RAM_RS24880	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
RAM_RS24890	COG1262	PFAM Formylglycine-generating sulfatase enzyme
RAM_RS24895	COG3572	ergothioneine biosynthetic process
RAM_RS24905	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
RAM_RS24910	COG2267	carboxylic ester hydrolase activity
RAM_RS24935	COG1309	transcriptional regulator
RAM_RS24975	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
RAM_RS24995	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
RAM_RS24995	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
RAM_RS25015	COG0789	Transcriptional regulator
RAM_RS25030	COG1716	ATPase activity
RAM_RS25060	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RAM_RS25065	COG1024	Enoyl-CoA hydratase
RAM_RS25075	COG1648	precorrin-2 dehydrogenase activity
RAM_RS25075	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
RAM_RS25090	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
RAM_RS25095	COG0267	Belongs to the bacterial ribosomal protein bL33 family
RAM_RS25100	COG0254	rRNA binding
RAM_RS25120	COG2814	Major facilitator Superfamily
RAM_RS25140	COG2211	Major facilitator Superfamily
RAM_RS25145	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RAM_RS25180	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RAM_RS25190	COG1116	anion transmembrane transporter activity
RAM_RS25195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RAM_RS25200	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RAM_RS25205	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
RAM_RS25230	COG1132	(ABC) transporter
RAM_RS25245	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
RAM_RS25255	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RAM_RS25260	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RAM_RS25265	COG1120	ATPase activity
RAM_RS25275	COG3486	L-lysine 6-monooxygenase (NADPH) activity
RAM_RS25305	COG0395	ABC-type sugar transport system, permease component
RAM_RS25310	COG0488	(ABC) transporter
RAM_RS25355	COG3293	Transposase
RAM_RS25425	COG3250	beta-galactosidase activity
RAM_RS25445	COG4948	Mandelate Racemase Muconate Lactonizing
RAM_RS25455	COG4948	Mandelate Racemase Muconate Lactonizing
RAM_RS25460	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RAM_RS25470	COG1116	anion transmembrane transporter activity
RAM_RS25475	COG2205	protein histidine kinase activity
RAM_RS25480	COG0745	RESPONSE REGULATOR receiver
RAM_RS25510	COG1846	Transcriptional regulator
RAM_RS25525	COG0028	Belongs to the TPP enzyme family
RAM_RS25530	COG1073	alpha beta
RAM_RS25535	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS25540	COG0179	Fumarylacetoacetate (FAA) hydrolase
RAM_RS25550	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RAM_RS25570	COG1129	ABC transporter
RAM_RS25575	COG1172	Belongs to the binding-protein-dependent transport system permease family
RAM_RS25595	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
RAM_RS25620	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RAM_RS25625	COG0463	Glycosyl transferase, family 2
RAM_RS25635	COG3250	beta-galactosidase activity
RAM_RS25660	COG4221	oxidoreductase activity
RAM_RS25685	COG0709	Synthesizes selenophosphate from selenide and ATP
RAM_RS25715	COG2367	Beta-lactamase
RAM_RS25720	COG2249	NAD(P)H dehydrogenase (quinone) activity
RAM_RS25735	COG2267	carboxylic ester hydrolase activity
RAM_RS25770	COG0596	Alpha beta hydrolase
RAM_RS25775	COG1309	transcriptional regulator
RAM_RS25830	COG2409	Drug exporters of the RND superfamily
RAM_RS25850	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
RAM_RS25855	COG0019	diaminopimelate decarboxylase activity
RAM_RS25905	COG2201	protein-glutamate methylesterase activity
RAM_RS25910	COG4585	Histidine kinase
RAM_RS25920	COG2197	response regulator
RAM_RS25935	COG1324	tolerance protein
RAM_RS25990	COG2814	Major facilitator Superfamily
RAM_RS26025	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
RAM_RS26030	COG0667	Aldo Keto reductase
RAM_RS26055	COG5297	Belongs to the glycosyl hydrolase family 6
RAM_RS26060	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
RAM_RS26065	COG5297	Belongs to the glycosyl hydrolase family 6
RAM_RS26065	COG4733	cellulase activity
RAM_RS26085	COG0395	ABC-type sugar transport system, permease component
RAM_RS26095	COG0129	dihydroxy-acid dehydratase activity
RAM_RS26110	COG1573	uracil-dna glycosylase
RAM_RS26115	COG3285	dna ligase
RAM_RS26115	COG1793	dna ligase
RAM_RS26125	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
RAM_RS26225	COG0583	DNA-binding transcription factor activity
RAM_RS26230	COG0019	diaminopimelate decarboxylase activity
RAM_RS26255	COG0477	Major facilitator Superfamily
RAM_RS26260	COG0456	acetyltransferase
RAM_RS26270	COG4104	PAAR repeat-containing protein
RAM_RS26270	COG3209	COG3209 Rhs family protein
RAM_RS26350	COG1472	Belongs to the glycosyl hydrolase 3 family
RAM_RS26380	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
RAM_RS26410	COG0456	acetyltransferase
RAM_RS26415	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
RAM_RS26430	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
RAM_RS26450	COG2018	Roadblock/LC7 domain
RAM_RS26455	COG2205	protein histidine kinase activity
RAM_RS26490	COG3903	Transcriptional regulator
RAM_RS26490	COG3629	intracellular signal transduction
RAM_RS26515	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RAM_RS26535	COG1024	Enoyl-CoA hydratase
RAM_RS26535	COG1250	3-hydroxyacyl-CoA dehydrogenase
RAM_RS26565	COG0402	S-adenosylhomocysteine deaminase activity
RAM_RS26570	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
RAM_RS26575	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
RAM_RS26580	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RAM_RS26585	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RAM_RS26590	COG1862	Preprotein translocase
RAM_RS26595	COG2255	four-way junction helicase activity
RAM_RS26600	COG0632	four-way junction helicase activity
RAM_RS26605	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
RAM_RS26620	COG0217	transcriptional regulatory protein
RAM_RS26625	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
RAM_RS26640	COG1396	sequence-specific DNA binding
RAM_RS26645	COG0644	oxidoreductase
RAM_RS26650	COG1960	acyl-CoA dehydrogenase activity
RAM_RS26670	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
RAM_RS26680	COG0277	FAD linked oxidase domain protein
RAM_RS26690	COG3608	succinylglutamate desuccinylase aspartoacylase
RAM_RS26690	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
RAM_RS26710	COG0438	transferase activity, transferring glycosyl groups
RAM_RS26735	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
RAM_RS26740	COG0778	Nitroreductase
RAM_RS26780	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RAM_RS26785	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RAM_RS26790	COG0701	Predicted permease
RAM_RS26810	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS26820	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RAM_RS26835	COG1473	amidohydrolase
RAM_RS26850	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
RAM_RS26865	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RAM_RS26875	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_RS26910	COG1597	lipid kinase activity
RAM_RS26945	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RAM_RS26950	COG0395	ABC-type sugar transport system, permease component
RAM_RS26955	COG1175	transmembrane transport
RAM_RS26970	COG2072	flavoprotein involved in K transport
RAM_RS26985	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS27040	COG2211	Major facilitator Superfamily
RAM_RS27045	COG1802	Transcriptional regulator
RAM_RS27085	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
RAM_RS27125	COG3483	tryptophan 2,3-dioxygenase activity
RAM_RS27140	COG2197	response regulator
RAM_RS27145	COG4585	Histidine kinase
RAM_RS27155	COG1131	(ABC) transporter
RAM_RS27165	COG3510	cephalosporin hydroxylase
RAM_RS27170	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RAM_RS27180	COG1819	glycosyl
RAM_RS27190	COG1819	glycosyl
RAM_RS27230	COG3629	intracellular signal transduction
RAM_RS27235	COG1819	glycosyl
RAM_RS27240	COG3848	Pyruvate phosphate dikinase
RAM_RS27240	COG0574	Belongs to the PEP-utilizing enzyme family
RAM_RS27255	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS27275	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS27285	COG2867	negative regulation of translational initiation
RAM_RS27290	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RAM_RS27295	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
RAM_RS27300	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
RAM_RS27305	COG0662	Cupin 2, conserved barrel domain protein
RAM_RS27320	COG3104	oligopeptide transport
RAM_RS27325	COG2345	Transcriptional regulator
RAM_RS27330	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RAM_RS27350	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS27425	COG0659	secondary active sulfate transmembrane transporter activity
RAM_RS27435	COG0589	response to stress
RAM_RS27455	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
RAM_RS27470	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
RAM_RS27495	COG1271	oxidase subunit
RAM_RS27500	COG1294	oxidase, subunit
RAM_RS27505	COG4988	ABC transporter
RAM_RS27510	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
RAM_RS27520	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
RAM_RS27520	COG0617	tRNA 3'-terminal CCA addition
RAM_RS27520	COG0517	IMP dehydrogenase activity
RAM_RS27555	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
RAM_RS27575	COG4585	Histidine kinase
RAM_RS27580	COG2197	response regulator
RAM_RS27600	COG4585	Histidine kinase
RAM_RS27605	COG2197	response regulator
RAM_RS27660	COG2197	response regulator
RAM_RS27700	COG0681	Belongs to the peptidase S26 family
RAM_RS27705	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS27765	COG0405	Gamma-glutamyltransferase
RAM_RS27770	COG3706	GGDEF domain
RAM_RS27815	COG1216	Glycosyl transferase, family 2
RAM_RS27820	COG1215	transferase activity, transferring glycosyl groups
RAM_RS27830	COG1132	(ABC) transporter
RAM_RS27845	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RAM_RS27850	COG0596	Alpha beta hydrolase
RAM_RS27905	COG2814	Major facilitator Superfamily
RAM_RS27920	COG3629	intracellular signal transduction
RAM_RS27920	COG3903	Transcriptional regulator
RAM_RS27995	COG0330	HflC and HflK could
RAM_RS28070	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
RAM_RS28130	COG0297	glycogen (starch) synthase activity
RAM_RS28135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RAM_RS28165	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS28170	COG1309	transcriptional regulator
RAM_RS28175	COG4941	Belongs to the sigma-70 factor family
RAM_RS28180	COG4941	Belongs to the sigma-70 factor family
RAM_RS28205	COG0583	DNA-binding transcription factor activity
RAM_RS28245	COG0515	serine threonine protein kinase
RAM_RS28250	COG1595	DNA-templated transcription, initiation
RAM_RS28255	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
RAM_RS28310	COG0596	Alpha beta hydrolase
RAM_RS28315	COG0596	Alpha beta hydrolase
RAM_RS28325	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
RAM_RS28340	COG1672	PFAM Archaeal ATPase
RAM_RS28340	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
RAM_RS28345	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS28370	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS28400	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
RAM_RS28460	COG2205	protein histidine kinase activity
RAM_RS28465	COG0745	RESPONSE REGULATOR receiver
RAM_RS28470	COG1216	Glycosyl transferase, family 2
RAM_RS28475	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
RAM_RS28500	COG1609	Transcriptional regulator
RAM_RS28510	COG1309	transcriptional regulator
RAM_RS28565	COG4941	Belongs to the sigma-70 factor family
RAM_RS28585	COG1335	isochorismatase
RAM_RS28615	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RAM_RS28620	COG1309	transcriptional regulator
RAM_RS28635	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
RAM_RS28640	COG1414	Transcriptional regulator
RAM_RS28645	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS28665	COG1278	Cold shock
RAM_RS28680	COG0300	oxidoreductase activity
RAM_RS28690	COG3795	YCII-related domain
RAM_RS28705	COG3263	regulation of cellular component size
RAM_RS28715	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
RAM_RS28725	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
RAM_RS28765	COG0745	RESPONSE REGULATOR receiver
RAM_RS28770	COG5000	phosphorelay sensor kinase activity
RAM_RS28770	COG5002	protein histidine kinase activity
RAM_RS28795	COG1846	Transcriptional regulator
RAM_RS28800	COG0038	chloride channel
RAM_RS28830	COG0243	molybdopterin cofactor binding
RAM_RS28830	COG3383	formate dehydrogenase (NAD+) activity
RAM_RS28835	COG0243	molybdopterin cofactor binding
RAM_RS28835	COG3383	formate dehydrogenase (NAD+) activity
RAM_RS28840	COG0437	4 iron, 4 sulfur cluster binding
RAM_RS28875	COG2116	formate transmembrane transporter activity
RAM_RS28900	COG0531	amino acid
RAM_RS28905	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
RAM_RS28925	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
RAM_RS28930	COG2080	2 iron, 2 sulfur cluster binding
RAM_RS28940	COG0667	Aldo Keto reductase
RAM_RS28985	COG3250	beta-galactosidase activity
RAM_RS28990	COG0395	ABC-type sugar transport system, permease component
RAM_RS28995	COG1175	transmembrane transport
RAM_RS29000	COG1609	Transcriptional regulator
RAM_RS29005	COG1609	Transcriptional regulator
RAM_RS29025	COG1609	Transcriptional regulator
RAM_RS29045	COG1917	Cupin 2, conserved barrel domain protein
RAM_RS29045	COG2207	Transcriptional regulator
RAM_RS29050	COG3250	beta-galactosidase activity
RAM_RS29180	COG3293	Transposase
RAM_RS29205	COG1857	crispr-associated protein
RAM_RS29320	COG5297	Belongs to the glycosyl hydrolase family 6
RAM_RS29320	COG4733	cellulase activity
RAM_RS29345	COG0154	amidase activity
RAM_RS29350	COG0789	Transcriptional regulator
RAM_RS29355	COG0640	Transcriptional regulator
RAM_RS29385	COG0673	inositol 2-dehydrogenase activity
RAM_RS29410	COG1653	transport
RAM_RS29440	COG3842	ATPase activity
RAM_RS29450	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
RAM_RS29455	COG0028	Belongs to the TPP enzyme family
RAM_RS29475	COG2197	response regulator
RAM_RS29485	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
RAM_RS29495	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RAM_RS29505	COG0702	epimerase
RAM_RS29515	COG0583	DNA-binding transcription factor activity
RAM_RS29530	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
RAM_RS29590	COG0300	oxidoreductase activity
RAM_RS29595	COG4221	oxidoreductase activity
RAM_RS29600	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
RAM_RS29660	COG2318	DinB family
RAM_RS29665	COG0667	Aldo Keto reductase
RAM_RS29680	COG2267	carboxylic ester hydrolase activity
RAM_RS29690	COG3629	intracellular signal transduction
RAM_RS29690	COG3903	Transcriptional regulator
RAM_RS29750	COG4974	Belongs to the 'phage' integrase family
RAM_RS29755	COG1012	belongs to the aldehyde dehydrogenase family
RAM_RS29805	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
RAM_RS29845	COG0515	serine threonine protein kinase
RAM_RS29845	COG2815	serine threonine protein kinase
RAM_RS29860	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
RAM_RS29890	COG3511	phospholipase C
RAM_RS29940	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS29990	COG0714	Associated with various cellular activities
RAM_RS30000	COG3552	Protein containing von Willebrand factor type A (VWA) domain
RAM_RS30005	COG0257	Belongs to the bacterial ribosomal protein bL36 family
RAM_RS30015	COG1733	regulation of RNA biosynthetic process
RAM_RS30025	COG5492	domain, Protein
RAM_RS30040	COG4948	Mandelate Racemase Muconate Lactonizing
RAM_RS30045	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RAM_RS30055	COG1414	Transcriptional regulator
RAM_RS30060	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RAM_RS30160	COG1160	GTP binding
RAM_RS30190	COG0475	glutathione-regulated potassium exporter activity
RAM_RS30195	COG2936	dipeptidyl-peptidase activity
RAM_RS30200	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
RAM_RS30210	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
RAM_RS30240	COG0494	nUDIX hydrolase
RAM_RS30245	COG0504	CTP synthase activity
RAM_RS30255	COG1802	Transcriptional regulator
RAM_RS30260	COG1953	Uracil, thiamine, allantoin
RAM_RS30295	COG1063	alcohol dehydrogenase
RAM_RS30310	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
RAM_RS30325	COG0647	UMP catabolic process
RAM_RS30350	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
RAM_RS30355	COG2094	Belongs to the DNA glycosylase MPG family
RAM_RS30375	COG0165	Argininosuccinate lyase
RAM_RS30380	COG0137	argininosuccinate synthase activity
RAM_RS30385	COG1438	arginine binding
RAM_RS30390	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
RAM_RS30395	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
RAM_RS30400	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
RAM_RS30405	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
RAM_RS30410	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
RAM_RS30425	COG0596	Alpha beta hydrolase
RAM_RS30435	COG0072	phenylalanine-tRNA ligase activity
RAM_RS30435	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RAM_RS30440	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
RAM_RS30450	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RAM_RS30455	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
RAM_RS30460	COG0291	Belongs to the bacterial ribosomal protein bL35 family
RAM_RS30505	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
RAM_RS30510	COG2610	gluconate transmembrane transporter activity
RAM_RS30515	COG2706	6-phosphogluconolactonase activity
RAM_RS30525	COG1175	transmembrane transport
RAM_RS30530	COG0395	ABC-type sugar transport system, permease component
RAM_RS30545	COG4565	transcriptional regulatory protein
RAM_RS30550	COG3290	protein histidine kinase activity
RAM_RS30555	COG1301	dicarboxylic acid transport
RAM_RS30605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RAM_RS30630	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RAM_RS30635	COG0328	RNA-DNA hybrid ribonuclease activity
RAM_RS30640	COG3012	SEC-C Motif Domain Protein
RAM_RS30650	COG3250	beta-galactosidase activity
RAM_RS30655	COG2272	Belongs to the type-B carboxylesterase lipase family
RAM_RS30670	COG0406	alpha-ribazole phosphatase activity
RAM_RS30690	COG1609	Transcriptional regulator
RAM_RS30710	COG1506	peptidase
RAM_RS30710	COG4946	Tricorn protease homolog
RAM_RS30710	COG0823	Involved in the tonB-independent uptake of proteins
RAM_RS30720	COG1131	(ABC) transporter
RAM_RS30740	COG1024	Enoyl-CoA hydratase
RAM_RS30780	COG0237	dephospho-CoA kinase activity
RAM_RS30780	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
RAM_RS30805	COG0539	negative regulation of cytoplasmic translation
RAM_RS30810	COG2226	methyltransferase
RAM_RS30830	COG1511	domain protein
RAM_RS30835	COG1309	transcriptional regulator
RAM_RS30840	COG2207	Transcriptional regulator
RAM_RS30845	COG0604	alcohol dehydrogenase
RAM_RS30870	COG0583	DNA-binding transcription factor activity
RAM_RS31140	COG4585	Histidine kinase
RAM_RS31145	COG2197	response regulator
RAM_RS31165	COG2197	response regulator
RAM_RS31170	COG4585	Histidine kinase
RAM_RS31190	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RAM_RS31195	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
RAM_RS31215	COG1454	alcohol dehydrogenase
RAM_RS31225	COG1012	belongs to the aldehyde dehydrogenase family
RAM_RS31245	COG0596	Alpha beta hydrolase
RAM_RS31265	COG4977	sequence-specific DNA binding
RAM_RS31270	COG0596	Alpha beta hydrolase
RAM_RS31280	COG0300	oxidoreductase activity
RAM_RS31320	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RAM_RS31365	COG3251	PFAM MbtH domain protein
RAM_RS31420	COG2814	Major facilitator Superfamily
RAM_RS31425	COG0702	epimerase
RAM_RS31435	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
RAM_RS31440	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
RAM_RS31450	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
RAM_RS31455	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
RAM_RS31470	COG0768	penicillin binding
RAM_RS31480	COG0275	rRNA processing
RAM_RS31485	COG2001	Belongs to the MraZ family
RAM_RS31515	COG0714	Associated with various cellular activities
RAM_RS31525	COG1305	Transglutaminase-like
RAM_RS31535	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
RAM_RS31545	COG1192	Involved in chromosome partitioning
RAM_RS31550	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
RAM_RS31555	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
RAM_RS31565	COG0167	dihydroorotate dehydrogenase activity
RAM_RS31580	COG1842	Phage shock protein A
RAM_RS31585	COG1396	sequence-specific DNA binding
RAM_RS31590	COG1546	Belongs to the CinA family
RAM_RS31590	COG1058	Belongs to the CinA family
RAM_RS31600	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
RAM_RS31605	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
RAM_RS31635	COG1674	ftsk spoiiie
RAM_RS31645	COG0655	NAD(P)H dehydrogenase (quinone) activity
RAM_RS31665	COG1113	amino acid transport
RAM_RS31675	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
RAM_RS31680	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RAM_RS31685	COG0515	serine threonine protein kinase
RAM_RS31720	COG3214	Protein conserved in bacteria
RAM_RS31760	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
RAM_RS31770	COG1185	polyribonucleotide nucleotidyltransferase activity
RAM_RS31775	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
RAM_RS31795	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
RAM_RS31820	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
RAM_RS31830	COG2268	Band 7 protein
RAM_RS31845	COG2226	methyltransferase
RAM_RS31880	COG0195	Participates in both transcription termination and antitermination
RAM_RS31885	COG0779	Required for maturation of 30S ribosomal subunits
RAM_RS31915	COG3226	Transcriptional regulator
RAM_RS31925	COG4585	Histidine kinase
RAM_RS31930	COG2197	response regulator
RAM_RS31940	COG1733	regulation of RNA biosynthetic process
RAM_RS31950	COG1309	transcriptional regulator
RAM_RS31955	COG2936	dipeptidyl-peptidase activity
RAM_RS31970	COG0745	RESPONSE REGULATOR receiver
RAM_RS31975	COG5002	protein histidine kinase activity
RAM_RS31985	COG3903	Transcriptional regulator
RAM_RS31985	COG3629	intracellular signal transduction
RAM_RS32005	COG0583	DNA-binding transcription factor activity
RAM_RS32015	COG1024	Enoyl-CoA hydratase
RAM_RS32025	COG1250	3-hydroxyacyl-CoA dehydrogenase
RAM_RS32030	COG1960	acyl-CoA dehydrogenase activity
RAM_RS32035	COG1316	TRANSCRIPTIONal
RAM_RS32065	COG0583	DNA-binding transcription factor activity
RAM_RS32090	COG2124	cytochrome p450
RAM_RS32105	COG0702	epimerase
RAM_RS32130	COG3629	intracellular signal transduction
RAM_RS32130	COG3903	Transcriptional regulator
RAM_RS32180	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RAM_RS32220	COG1595	DNA-templated transcription, initiation
RAM_RS32245	COG3507	Belongs to the glycosyl hydrolase 43 family
RAM_RS32260	COG4941	Belongs to the sigma-70 factor family
RAM_RS32265	COG3795	YCII-related domain
RAM_RS32270	COG0596	Alpha beta hydrolase
RAM_RS32275	COG1309	transcriptional regulator
RAM_RS32280	COG0604	alcohol dehydrogenase
RAM_RS32305	COG0443	Heat shock 70 kDa protein
RAM_RS32320	COG1228	amidohydrolase
RAM_RS32360	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
RAM_RS32390	COG2197	response regulator
RAM_RS32420	COG2755	lipolytic protein G-D-S-L family
RAM_RS32420	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
RAM_RS32470	COG3629	intracellular signal transduction
RAM_RS32470	COG3903	Transcriptional regulator
RAM_RS32495	COG0667	Aldo Keto reductase
RAM_RS32525	COG1960	acyl-CoA dehydrogenase activity
RAM_RS32540	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_RS32555	COG0596	Alpha beta hydrolase
RAM_RS32560	COG2197	response regulator
RAM_RS32585	COG0477	Major facilitator Superfamily
RAM_RS32625	COG1131	(ABC) transporter
RAM_RS32635	COG4585	Histidine kinase
RAM_RS32640	COG2197	response regulator
RAM_RS32655	COG0586	Pfam SNARE associated Golgi protein
RAM_RS32665	COG1968	undecaprenyl-diphosphatase activity
RAM_RS32695	COG1131	(ABC) transporter
RAM_RS32705	COG4585	Histidine kinase
RAM_RS32710	COG2197	response regulator
RAM_RS32720	COG2201	protein-glutamate methylesterase activity
RAM_RS32735	COG1309	transcriptional regulator
RAM_RS32740	COG0702	epimerase
RAM_RS32745	COG0702	epimerase
RAM_RS32760	COG0657	acetylesterase activity
RAM_RS32770	COG2814	Major facilitator Superfamily
RAM_RS32795	COG4977	sequence-specific DNA binding
RAM_RS32850	COG1120	ATPase activity
RAM_RS32855	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RAM_RS32970	COG0243	molybdopterin cofactor binding
RAM_RS33020	COG0028	Belongs to the TPP enzyme family
RAM_RS33025	COG4948	Mandelate Racemase Muconate Lactonizing
RAM_RS33030	COG0247	lactate metabolic process
RAM_RS33030	COG0277	FAD linked oxidase domain protein
RAM_RS33055	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
RAM_RS33060	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
RAM_RS33070	COG1659	Linocin_M18 bacteriocin protein
RAM_RS33090	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
RAM_RS33110	COG4106	trans-aconitate 2-methyltransferase activity
RAM_RS33125	COG1595	DNA-templated transcription, initiation
RAM_RS33140	COG0477	Major facilitator Superfamily
RAM_RS33160	COG2318	DinB family
RAM_RS33175	COG0232	Belongs to the dGTPase family. Type 2 subfamily
RAM_RS33185	COG2197	response regulator
RAM_RS33190	COG4585	Histidine kinase
RAM_RS33200	COG1131	(ABC) transporter
RAM_RS33205	COG0423	glycine-tRNA ligase activity
RAM_RS33245	COG0701	Predicted permease
RAM_RS33255	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
RAM_RS33260	COG1381	Involved in DNA repair and RecF pathway recombination
RAM_RS33290	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
RAM_RS33305	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
RAM_RS33315	COG0537	adenosine 5'-monophosphoramidase activity
RAM_RS33325	COG0484	heat shock protein binding
RAM_RS33355	COG0667	Aldo Keto reductase
RAM_RS33390	COG2205	protein histidine kinase activity
RAM_RS33395	COG0745	RESPONSE REGULATOR receiver
RAM_RS33400	COG1953	Uracil, thiamine, allantoin
RAM_RS33410	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
RAM_RS33500	COG0326	Molecular chaperone. Has ATPase activity
RAM_RS33515	COG1024	Enoyl-CoA hydratase
RAM_RS33520	COG2732	(Barnase) inhibitor
RAM_RS33525	COG4290	ribonuclease
RAM_RS33535	COG0604	alcohol dehydrogenase
RAM_RS33545	COG0531	amino acid
RAM_RS33550	COG2070	2-Nitropropane dioxygenase
RAM_RS33610	COG0268	Binds directly to 16S ribosomal RNA
RAM_RS33620	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
RAM_RS33630	COG2333	competence protein COMEC
RAM_RS33630	COG0658	competence protein
RAM_RS33640	COG1307	EDD domain protein, DegV family
RAM_RS33650	COG0406	alpha-ribazole phosphatase activity
RAM_RS33655	COG0799	negative regulation of ribosome biogenesis
RAM_RS33660	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
RAM_RS33675	COG0018	arginyl-trna synthetase
RAM_RS33695	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS33705	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
RAM_RS33710	COG0211	Belongs to the bacterial ribosomal protein bL27 family
RAM_RS33715	COG0261	This protein binds to 23S rRNA in the presence of protein L20
RAM_RS33720	COG1530	ribonuclease E activity
RAM_RS33720	COG1530	ribonuclease E activity
RAM_RS33740	COG1131	(ABC) transporter
RAM_RS33755	COG0105	UTP biosynthetic process
RAM_RS33765	COG2366	antibiotic biosynthetic process
RAM_RS33775	COG0285	dihydrofolate synthase activity
RAM_RS33800	COG0583	DNA-binding transcription factor activity
RAM_RS33805	COG0525	valine-tRNA ligase activity
RAM_RS33815	COG1846	Transcriptional regulator
RAM_RS33820	COG0477	Major facilitator Superfamily
RAM_RS33835	COG1316	TRANSCRIPTIONal
RAM_RS33845	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
RAM_RS33875	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
RAM_RS33880	COG0740	serine-type endopeptidase activity
RAM_RS33885	COG0740	serine-type endopeptidase activity
RAM_RS33890	COG0544	peptidyl-prolyl cis-trans isomerase activity
RAM_RS33900	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RAM_RS33910	COG2205	protein histidine kinase activity
RAM_RS33915	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
RAM_RS33970	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
RAM_RS34015	COG3629	intracellular signal transduction
RAM_RS34015	COG3903	Transcriptional regulator
RAM_RS34025	COG3537	Alpha-1,2-mannosidase
RAM_RS34030	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
RAM_RS34035	COG3559	Exporter of polyketide antibiotics
RAM_RS34040	COG1131	(ABC) transporter
RAM_RS34045	COG1309	transcriptional regulator
RAM_RS34055	COG1940	carbohydrate kinase activity
RAM_RS34075	COG2814	Major facilitator Superfamily
RAM_RS34110	COG0693	protein deglycase activity
RAM_RS34115	COG2208	phosphoserine phosphatase activity
RAM_RS34120	COG0784	Response regulator, receiver
RAM_RS34120	COG5002	protein histidine kinase activity
RAM_RS34140	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
RAM_RS34155	COG1396	sequence-specific DNA binding
RAM_RS34175	COG0583	DNA-binding transcription factor activity
RAM_RS34185	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS34195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RAM_RS34210	COG1733	regulation of RNA biosynthetic process
RAM_RS34215	COG3345	alpha-galactosidase
RAM_RS34240	COG0459	protein refolding
RAM_RS34250	COG0698	ribose 5-phosphate isomerase
RAM_RS34265	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
RAM_RS34280	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
RAM_RS34300	COG0668	transmembrane transport
RAM_RS34310	COG0366	Alpha amylase catalytic
RAM_RS34330	COG2902	Dehydrogenase
RAM_RS34345	COG3336	cytochrome c oxidase
RAM_RS34360	COG0738	Major facilitator superfamily
RAM_RS34375	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RAM_RS34380	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
RAM_RS34400	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
RAM_RS34440	COG0477	Major facilitator Superfamily
RAM_RS34445	COG0596	Alpha beta hydrolase
RAM_RS34465	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RAM_RS34485	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
RAM_RS34530	COG2124	cytochrome p450
RAM_RS34565	COG1733	regulation of RNA biosynthetic process
RAM_RS34570	COG4941	Belongs to the sigma-70 factor family
RAM_RS34575	COG3795	YCII-related domain
RAM_RS34585	COG0009	L-threonylcarbamoyladenylate synthase
RAM_RS34600	COG2197	response regulator
RAM_RS34605	COG1917	Cupin 2, conserved barrel domain protein
RAM_RS34605	COG4977	sequence-specific DNA binding
RAM_RS34610	COG2197	response regulator
RAM_RS34615	COG4585	Histidine kinase
RAM_RS34660	COG1937	Protein conserved in bacteria
RAM_RS34700	COG4221	oxidoreductase activity
RAM_RS34715	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
RAM_RS34740	COG0657	acetylesterase activity
RAM_RS34760	COG0745	RESPONSE REGULATOR receiver
RAM_RS34765	COG2205	protein histidine kinase activity
RAM_RS34775	COG1609	Transcriptional regulator
RAM_RS34795	COG0366	Alpha amylase catalytic
RAM_RS34810	COG0367	asparagine synthase
RAM_RS34815	COG1940	carbohydrate kinase activity
RAM_RS34835	COG0583	DNA-binding transcription factor activity
RAM_RS34875	COG1609	Transcriptional regulator
RAM_RS34910	COG0531	amino acid
RAM_RS34915	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RAM_RS34945	COG3835	regulator
RAM_RS34970	COG1021	2,3-dihydroxybenzoate-AMP ligase
RAM_RS34990	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
RAM_RS34995	COG0583	DNA-binding transcription factor activity
RAM_RS35040	COG1024	Enoyl-CoA hydratase
RAM_RS35100	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_RS35115	COG1643	Atp-dependent helicase
RAM_RS35130	COG3268	Saccharopine dehydrogenase
RAM_RS35135	COG2072	flavoprotein involved in K transport
RAM_RS35150	COG1796	DNA polymerase
RAM_RS35150	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
RAM_RS35160	COG1802	Transcriptional regulator
RAM_RS35185	COG3706	GGDEF domain
RAM_RS35195	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
RAM_RS35215	COG4941	Belongs to the sigma-70 factor family
RAM_RS35235	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
RAM_RS35250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RAM_RS35260	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
RAM_RS35265	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
RAM_RS35270	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
RAM_RS35270	COG0235	Class ii aldolase
RAM_RS35290	COG1695	Transcriptional regulator
RAM_RS35300	COG3959	Transketolase, thiamine diphosphate binding domain
RAM_RS35305	COG1309	transcriptional regulator
RAM_RS35310	COG0247	lactate metabolic process
RAM_RS35310	COG0277	FAD linked oxidase domain protein
RAM_RS35320	COG2197	response regulator
RAM_RS35340	COG0559	Belongs to the binding-protein-dependent transport system permease family
RAM_RS35345	COG0559	Belongs to the binding-protein-dependent transport system permease family
RAM_RS35360	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RAM_RS35365	COG3537	Alpha-1,2-mannosidase
RAM_RS35370	COG1739	Uncharacterized protein family UPF0029
RAM_RS35375	COG0069	glutamate synthase activity
RAM_RS35375	COG0070	glutamate synthase
RAM_RS35375	COG0067	glutamate synthase
RAM_RS35385	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RAM_RS35415	COG1492	cobalamin metabolic process
RAM_RS35420	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
RAM_RS35430	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
RAM_RS35435	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
RAM_RS35440	COG2378	regulation of single-species biofilm formation
RAM_RS35455	COG1797	cobyrinic acid a,c-diamide synthase activity
RAM_RS35490	COG0778	Nitroreductase
RAM_RS35520	COG1131	(ABC) transporter
RAM_RS35530	COG1476	TRANSCRIPTIONal
RAM_RS35545	COG3469	chitinase activity
RAM_RS35565	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
RAM_RS35590	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RAM_RS35600	COG0433	COG0433 Predicted ATPase
RAM_RS35605	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
RAM_RS35615	COG0477	Major facilitator Superfamily
RAM_RS35620	COG1376	ErfK ybiS ycfS ynhG family protein
RAM_RS35835	COG1960	acyl-CoA dehydrogenase activity
RAM_RS35845	COG0022	dehydrogenase e1 component
RAM_RS35850	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_RS35855	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS35860	COG1024	Enoyl-CoA hydratase
RAM_RS35880	COG0477	Major facilitator Superfamily
RAM_RS35890	COG2301	Belongs to the HpcH HpaI aldolase family
RAM_RS35900	COG2186	Transcriptional regulator
RAM_RS35905	COG1012	belongs to the aldehyde dehydrogenase family
RAM_RS35910	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RAM_RS35925	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS35960	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RAM_RS35970	COG1309	transcriptional regulator
RAM_RS35980	COG0604	alcohol dehydrogenase
RAM_RS36035	COG1960	acyl-CoA dehydrogenase activity
RAM_RS36040	COG1960	acyl-CoA dehydrogenase activity
RAM_RS36050	COG2186	Transcriptional regulator
RAM_RS36065	COG3321	synthase
RAM_RS36065	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS36065	COG0604	alcohol dehydrogenase
RAM_RS36070	COG1960	acyl-CoA dehydrogenase activity
RAM_RS36075	COG1960	acyl-CoA dehydrogenase activity
RAM_RS36115	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RAM_RS36130	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS36160	COG1414	Transcriptional regulator
RAM_RS36170	COG2267	carboxylic ester hydrolase activity
RAM_RS36185	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS36190	COG0259	pyridoxamine-phosphate oxidase activity
RAM_RS36195	COG0183	Belongs to the thiolase family
RAM_RS36200	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RAM_RS36205	COG1024	Enoyl-CoA hydratase
RAM_RS36210	COG1960	acyl-CoA dehydrogenase activity
RAM_RS36225	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_RS36235	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_RS36245	COG1024	Enoyl-CoA hydratase
RAM_RS36255	COG1024	Enoyl-CoA hydratase
RAM_RS36275	COG1024	Enoyl-CoA hydratase
RAM_RS36285	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
RAM_RS36295	COG1012	belongs to the aldehyde dehydrogenase family
RAM_RS36315	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RAM_RS36350	COG1335	isochorismatase
RAM_RS36370	COG1309	transcriptional regulator
RAM_RS36380	COG0022	dehydrogenase e1 component
RAM_RS36410	COG1063	alcohol dehydrogenase
RAM_RS36420	COG4585	Histidine kinase
RAM_RS36425	COG2197	response regulator
RAM_RS36445	COG4948	Mandelate Racemase Muconate Lactonizing
RAM_RS36450	COG2271	Major facilitator Superfamily
RAM_RS36480	COG0235	Class ii aldolase
RAM_RS36485	COG0477	Major facilitator Superfamily
RAM_RS36490	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
RAM_RS36520	COG0673	inositol 2-dehydrogenase activity
RAM_RS36525	COG2211	Major facilitator Superfamily
RAM_RS36530	COG1609	Transcriptional regulator
RAM_RS36535	COG1653	transport
RAM_RS36545	COG0395	ABC-type sugar transport system, permease component
RAM_RS36555	COG0596	Alpha beta hydrolase
RAM_RS36565	COG0596	Alpha beta hydrolase
RAM_RS36580	COG2084	Dehydrogenase
RAM_RS36590	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RAM_RS36595	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
RAM_RS36605	COG0189	ligase activity
RAM_RS36620	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RAM_RS36625	COG0625	glutathione transferase activity
RAM_RS36635	COG2271	Major facilitator Superfamily
RAM_RS36650	COG1250	3-hydroxyacyl-CoA dehydrogenase
RAM_RS36835	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
RAM_RS36880	COG2856	Zn peptidase
RAM_RS36915	COG0702	epimerase
RAM_RS36930	COG0702	epimerase
RAM_RS36940	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
RAM_RS36945	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
RAM_RS36950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RAM_RS36955	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS36960	COG2169	Transcriptional regulator
RAM_RS36960	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
RAM_RS37030	COG4733	cellulase activity
RAM_RS37030	COG5297	Belongs to the glycosyl hydrolase family 6
RAM_RS37040	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
RAM_RS37060	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
RAM_RS37095	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
RAM_RS37100	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
RAM_RS37120	COG1960	acyl-CoA dehydrogenase activity
RAM_RS37145	COG0154	amidase activity
RAM_RS37160	COG0583	DNA-binding transcription factor activity
RAM_RS37200	COG1131	(ABC) transporter
RAM_RS37210	COG3345	alpha-galactosidase
RAM_RS37255	COG0438	transferase activity, transferring glycosyl groups
RAM_RS37275	COG0297	glycogen (starch) synthase activity
RAM_RS37280	COG0438	transferase activity, transferring glycosyl groups
RAM_RS37295	COG0463	Glycosyl transferase, family 2
RAM_RS37330	COG3250	beta-galactosidase activity
RAM_RS37335	COG3401	FG-GAP repeat protein
RAM_RS37355	COG1609	Transcriptional regulator
RAM_RS37365	COG0395	ABC-type sugar transport system, permease component
RAM_RS37370	COG1175	transmembrane transport
RAM_RS37410	COG0596	Alpha beta hydrolase
RAM_RS37415	COG2770	Histidine kinase
RAM_RS37415	COG2208	phosphoserine phosphatase activity
RAM_RS37425	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RAM_RS37435	COG2226	methyltransferase
RAM_RS37445	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
RAM_RS37485	COG0667	Aldo Keto reductase
RAM_RS37490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RAM_RS37510	COG0587	DNA-directed DNA polymerase activity
RAM_RS37515	COG4941	Belongs to the sigma-70 factor family
RAM_RS37520	COG3795	YCII-related domain
RAM_RS37530	COG1982	Orn Lys Arg decarboxylase major
RAM_RS37545	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
RAM_RS37555	COG1725	Transcriptional regulator
RAM_RS37560	COG1131	(ABC) transporter
RAM_RS37580	COG3509	depolymerase
RAM_RS37595	COG1528	Iron-storage protein
RAM_RS37620	COG2018	Roadblock/LC7 domain
RAM_RS37645	COG1764	response to oxidative stress
RAM_RS37655	COG2267	carboxylic ester hydrolase activity
RAM_RS37670	COG0667	Aldo Keto reductase
RAM_RS37675	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
RAM_RS37710	COG0395	ABC-type sugar transport system, permease component
RAM_RS37715	COG1175	transmembrane transport
RAM_RS37720	COG1609	Transcriptional regulator
RAM_RS37745	COG0604	alcohol dehydrogenase
RAM_RS37775	COG1595	DNA-templated transcription, initiation
RAM_RS37785	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_RS37790	COG0129	dihydroxy-acid dehydratase activity
RAM_RS37795	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
RAM_RS37850	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
RAM_RS37885	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RAM_RS37895	COG2226	methyltransferase
RAM_RS37900	COG2508	Transcriptional regulator
RAM_RS37910	COG3655	Transcriptional regulator
RAM_RS37955	COG4981	capsule polysaccharide biosynthetic process
RAM_RS37980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RAM_RS37985	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RAM_RS38010	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RAM_RS38045	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
RAM_RS38060	COG3226	Transcriptional regulator
RAM_RS38065	COG1012	belongs to the aldehyde dehydrogenase family
RAM_RS38120	COG0508	dehydrogenase complex catalyzes the overall conversion of
RAM_RS38145	COG1472	Belongs to the glycosyl hydrolase 3 family
RAM_RS38160	COG0745	RESPONSE REGULATOR receiver
RAM_RS38165	COG5002	protein histidine kinase activity
RAM_RS38195	COG2815	serine threonine protein kinase
RAM_RS38195	COG0515	serine threonine protein kinase
RAM_RS38215	COG0640	Transcriptional regulator
RAM_RS38225	COG2837	iron assimilation
RAM_RS38230	COG3511	phospholipase C
RAM_RS38245	COG0784	Response regulator, receiver
RAM_RS38250	COG4251	negative regulation of phosphorylation
RAM_RS38255	COG0745	RESPONSE REGULATOR receiver
RAM_RS38335	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
RAM_RS38360	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
RAM_RS38435	COG1309	transcriptional regulator
RAM_RS38460	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
RAM_RS38465	COG1309	transcriptional regulator
RAM_RS38485	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_RS38490	COG3383	formate dehydrogenase (NAD+) activity
RAM_RS38495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RAM_RS38540	COG2814	Major facilitator Superfamily
RAM_RS38605	COG0706	membrane insertase activity
RAM_RS38615	COG1408	metallophosphoesterase
RAM_RS38625	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
RAM_RS38630	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RAM_RS38655	COG2018	Roadblock/LC7 domain
RAM_RS38675	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS38685	COG3706	GGDEF domain
RAM_RS38700	COG1316	TRANSCRIPTIONal
RAM_RS38740	COG4977	sequence-specific DNA binding
RAM_RS38745	COG0667	Aldo Keto reductase
RAM_RS38750	COG2207	Transcriptional regulator
RAM_RS38780	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
RAM_RS38785	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
RAM_RS38790	COG1234	tRNA 3'-trailer cleavage
RAM_RS38795	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
RAM_RS38810	COG1794	racemase activity, acting on amino acids and derivatives
RAM_RS38815	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
RAM_RS38840	COG3191	aminopeptidase activity
RAM_RS38855	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
RAM_RS38860	COG1335	isochorismatase
RAM_RS38865	COG0800	Aldolase
RAM_RS38875	COG1268	BioY protein
RAM_RS38905	COG3830	Belongs to the UPF0237 family
RAM_RS38905	COG0560	Phosphoserine phosphatase
RAM_RS38910	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
RAM_RS38920	COG2267	carboxylic ester hydrolase activity
RAM_RS38940	COG2801	Transposase and inactivated derivatives
RAM_RS38955	COG0626	cystathionine gamma-synthase activity
RAM_RS38960	COG1522	sequence-specific DNA binding
RAM_RS38970	COG1522	sequence-specific DNA binding
RAM_RS39005	COG2376	Dihydroxyacetone kinase
RAM_RS39035	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
RAM_RS39040	COG1051	belongs to the nudix hydrolase family
RAM_RS39055	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
RAM_RS39060	COG4977	sequence-specific DNA binding
RAM_RS39065	COG1335	isochorismatase
RAM_RS39070	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
RAM_RS39070	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
RAM_RS39085	COG1280	lysine exporter protein (LysE YggA)
RAM_RS39090	COG1280	lysine exporter protein (LysE YggA)
RAM_RS39100	COG0702	epimerase
RAM_RS39105	COG3631	Ketosteroid isomerase-related protein
RAM_RS39110	COG1309	transcriptional regulator
RAM_RS39125	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
RAM_RS39135	COG0355	proton-transporting ATP synthase activity, rotational mechanism
RAM_RS39140	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
RAM_RS39145	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
RAM_RS39150	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
RAM_RS39155	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
RAM_RS39160	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
RAM_RS39165	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
RAM_RS39170	COG0356	it plays a direct role in the translocation of protons across the membrane
RAM_RS39180	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
RAM_RS39195	COG2890	protein-(glutamine-N5) methyltransferase activity
RAM_RS39200	COG0463	Glycosyl transferase, family 2
RAM_RS39220	COG0254	rRNA binding
RAM_RS39230	COG0083	homoserine kinase activity
RAM_RS39235	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
RAM_RS39240	COG0460	homoserine dehydrogenase
RAM_RS39245	COG0019	diaminopimelate decarboxylase activity
RAM_RS39250	COG0018	arginyl-trna synthetase
RAM_RS39285	COG0596	Alpha beta hydrolase
RAM_RS39365	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
RAM_RS39380	COG3903	Transcriptional regulator
RAM_RS39380	COG3629	intracellular signal transduction
RAM_RS39385	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
RAM_RS39385	COG2124	cytochrome p450
RAM_RS39405	COG3345	alpha-galactosidase
RAM_RS39425	COG3250	beta-galactosidase activity
RAM_RS39430	COG3693	PFAM glycoside hydrolase, family 10
RAM_RS39495	COG5433	transposase activity
RAM_RS39545	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RAM_RS39550	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RAM_RS39570	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS39580	COG0145	ligase activity
RAM_RS39605	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
RAM_RS39620	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
RAM_RS39635	COG0154	amidase activity
RAM_RS39665	COG0473	3-isopropylmalate dehydrogenase activity
RAM_RS39675	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
RAM_RS39685	COG0667	Aldo Keto reductase
RAM_RS39705	COG0028	Belongs to the TPP enzyme family
RAM_RS39730	COG4585	Histidine kinase
RAM_RS39735	COG2197	response regulator
RAM_RS39740	COG2409	Drug exporters of the RND superfamily
RAM_RS39745	COG3537	Alpha-1,2-mannosidase
RAM_RS39750	COG1250	3-hydroxyacyl-CoA dehydrogenase
RAM_RS39750	COG1024	Enoyl-CoA hydratase
RAM_RS39755	COG0183	Belongs to the thiolase family
RAM_RS39760	COG1309	transcriptional regulator
RAM_RS39795	COG1960	acyl-CoA dehydrogenase activity
RAM_RS39800	COG1960	acyl-CoA dehydrogenase activity
RAM_RS39860	COG4221	oxidoreductase activity
RAM_RS39890	COG1960	acyl-CoA dehydrogenase activity
RAM_RS39900	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
RAM_RS39930	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
RAM_RS39945	COG0346	lactoylglutathione lyase activity
RAM_RS39965	COG2226	methyltransferase
RAM_RS39970	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
RAM_RS39970	COG2508	Transcriptional regulator
RAM_RS39985	COG0686	Belongs to the AlaDH PNT family
RAM_RS39995	COG2205	protein histidine kinase activity
RAM_RS40005	COG0745	RESPONSE REGULATOR receiver
RAM_RS40020	COG1132	(ABC) transporter
RAM_RS40035	COG0567	Dehydrogenase, E1 component
RAM_RS40035	COG0508	dehydrogenase complex catalyzes the overall conversion of
RAM_RS40045	COG1216	Glycosyl transferase, family 2
RAM_RS40050	COG2223	nitrite transmembrane transporter activity
RAM_RS40060	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RAM_RS40075	COG1174	glycine betaine transport
RAM_RS40080	COG1174	glycine betaine transport
RAM_RS40085	COG0517	IMP dehydrogenase activity
RAM_RS40085	COG1125	glycine betaine transport
RAM_RS40100	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
RAM_RS40110	COG1846	Transcriptional regulator
RAM_RS40125	COG0406	alpha-ribazole phosphatase activity
RAM_RS40140	COG1597	lipid kinase activity
RAM_RS40165	COG1595	DNA-templated transcription, initiation
RAM_RS40170	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
RAM_RS40180	COG2135	peptidase activity
RAM_RS40210	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RAM_RS40215	COG1011	Hydrolase
RAM_RS40230	COG0653	protein targeting
RAM_RS40235	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
RAM_RS40245	COG5401	PFAM Sporulation and spore germination
RAM_RS40250	COG5002	protein histidine kinase activity
RAM_RS40250	COG5000	phosphorelay sensor kinase activity
RAM_RS40255	COG0745	RESPONSE REGULATOR receiver
RAM_RS40265	COG1414	Transcriptional regulator
RAM_RS40335	COG0531	amino acid
RAM_RS40345	COG3629	intracellular signal transduction
RAM_RS40345	COG3903	Transcriptional regulator
RAM_RS40350	COG1482	cell wall glycoprotein biosynthetic process
RAM_RS40360	COG2835	tetraacyldisaccharide 4'-kinase activity
RAM_RS40365	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
RAM_RS40405	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
RAM_RS40420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RAM_RS40425	COG0601	transmembrane transport
RAM_RS40435	COG0747	negative chemotaxis
RAM_RS40440	COG1217	gtp-binding protein TYPA
RAM_RS40450	COG0180	Tryptophanyl-tRNA synthetase
RAM_RS40455	COG0494	nUDIX hydrolase
RAM_RS40455	COG0406	alpha-ribazole phosphatase activity
RAM_RS40465	COG0745	RESPONSE REGULATOR receiver
RAM_RS40475	COG1131	(ABC) transporter
RAM_RS40485	COG3842	ATPase activity
RAM_RS40490	COG4149	molybdate abc transporter
RAM_RS40500	COG2154	pterin-4-alpha-carbinolamine dehydratase
RAM_RS40520	COG0012	GTP binding
RAM_RS40535	COG0419	ATPase involved in DNA repair
RAM_RS40540	COG0420	3'-5' exonuclease activity
RAM_RS40555	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
RAM_RS40565	COG1570	exodeoxyribonuclease VII activity
RAM_RS40575	COG1722	exodeoxyribonuclease VII activity
RAM_RS40590	COG0492	ferredoxin-NADP+ reductase activity
RAM_RS40595	COG0114	fumarate hydratase activity
RAM_RS40605	COG1793	dna ligase
RAM_RS40620	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RAM_RS40645	COG1228	amidohydrolase
RAM_RS40650	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
RAM_RS40675	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
RAM_RS40705	COG1331	Highly conserved protein containing a thioredoxin domain
RAM_RS40720	COG2890	protein-(glutamine-N5) methyltransferase activity
RAM_RS40725	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
RAM_RS40735	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
RAM_RS40745	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
RAM_RS40750	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RAM_RS40760	COG3185	4-Hydroxyphenylpyruvate dioxygenase
RAM_RS40790	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
RAM_RS40825	COG0183	Belongs to the thiolase family
RAM_RS40900	COG3903	Transcriptional regulator
RAM_RS40900	COG3629	intracellular signal transduction
RAM_RS40905	COG2723	6-phospho-beta-galactosidase activity
RAM_RS40915	COG1175	transmembrane transport
RAM_RS40930	COG1472	Belongs to the glycosyl hydrolase 3 family
RAM_RS40935	COG0667	Aldo Keto reductase
RAM_RS40945	COG0477	Major facilitator Superfamily
RAM_RS40975	COG2207	Transcriptional regulator
RAM_RS40990	COG5297	Belongs to the glycosyl hydrolase family 6
RAM_RS41005	COG2205	protein histidine kinase activity
RAM_RS41010	COG0148	phosphopyruvate hydratase activity
RAM_RS41020	COG1132	(ABC) transporter
RAM_RS41120	COG0515	serine threonine protein kinase
RAM_RS41120	COG2815	serine threonine protein kinase
RAM_RS41155	COG1191	sigma factor activity
RAM_RS41225	COG1515	deoxyribonuclease V activity
RAM_RS41240	COG4608	Belongs to the ABC transporter superfamily
RAM_RS41245	COG0444	Belongs to the ABC transporter superfamily
RAM_RS41250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RAM_RS41255	COG0601	transmembrane transport
RAM_RS41285	COG0148	phosphopyruvate hydratase activity
RAM_RS41305	COG0672	)-iron permease
RAM_RS41310	COG2822	iron ion transport
RAM_RS41315	COG2837	iron assimilation
RAM_RS41345	COG1131	(ABC) transporter
RAM_RS41395	COG0586	Pfam SNARE associated Golgi protein
RAM_RS41405	COG4585	Histidine kinase
RAM_RS41410	COG2197	response regulator
RAM_RS41415	COG2133	pyrroloquinoline quinone binding
RAM_RS41435	COG1051	belongs to the nudix hydrolase family
RAM_RS41460	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
RAM_RS41490	COG0193	aminoacyl-tRNA hydrolase activity
RAM_RS41495	COG3599	regulation of cell shape
RAM_RS41505	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_RS41510	COG0488	(ABC) transporter
RAM_RS41520	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
RAM_RS41525	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
RAM_RS41530	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
RAM_RS41535	COG3583	domain protein
RAM_RS41540	COG0084	hydrolase, TatD family'
RAM_RS41545	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RAM_RS41600	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
RAM_RS41605	COG2815	serine threonine protein kinase
RAM_RS41605	COG0515	serine threonine protein kinase
RAM_RS41625	COG2258	MOSC domain
RAM_RS41640	COG1595	DNA-templated transcription, initiation
RAM_RS41685	COG5001	Diguanylate cyclase
RAM_RS41695	COG2124	cytochrome p450
RAM_RS41700	COG1192	Involved in chromosome partitioning
RAM_RS41715	COG0702	epimerase
RAM_RS41725	COG0745	RESPONSE REGULATOR receiver
RAM_RS41730	COG2205	protein histidine kinase activity
RAM_RS41735	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
RAM_RS41740	COG1181	Belongs to the D-alanine--D-alanine ligase family
RAM_RS41750	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RAM_RS41755	COG1733	regulation of RNA biosynthetic process
RAM_RS41760	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
RAM_RS41765	COG3433	isochorismatase activity
RAM_RS41765	COG2226	methyltransferase
RAM_RS41765	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RAM_RS41780	COG1280	lysine exporter protein (LysE YggA)
RAM_RS41790	COG0515	serine threonine protein kinase
RAM_RS41845	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RAM_RS41855	COG1210	Utp--glucose-1-phosphate uridylyltransferase
RAM_RS41860	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
RAM_RS41885	COG0315	cyclic pyranopterin monophosphate synthase activity
RAM_RS41885	COG0521	Mo-molybdopterin cofactor biosynthetic process
RAM_RS41905	COG5002	protein histidine kinase activity
RAM_RS41910	COG0745	RESPONSE REGULATOR receiver
RAM_RS41930	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
RAM_RS41945	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RAM_RS41955	COG1349	DNA-binding transcription factor activity
RAM_RS41960	COG2205	protein histidine kinase activity
RAM_RS41965	COG0745	RESPONSE REGULATOR receiver
RAM_RS41970	COG2860	membrane
RAM_RS41975	COG2197	response regulator
RAM_RS41980	COG2264	protein methyltransferase activity
RAM_RS41990	COG0477	Major facilitator Superfamily
RAM_RS42000	COG0667	Aldo Keto reductase
RAM_RS42005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RAM_RS42020	COG2815	serine threonine protein kinase
RAM_RS42020	COG0515	serine threonine protein kinase
RAM_RS42025	COG0483	inositol monophosphate 1-phosphatase activity
RAM_RS42035	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
RAM_RS42050	COG0297	glycogen (starch) synthase activity
RAM_RS42070	COG3285	dna ligase
RAM_RS42070	COG1793	dna ligase
RAM_RS42080	COG0583	DNA-binding transcription factor activity
RAM_RS42090	COG2755	lipolytic protein G-D-S-L family
RAM_RS42090	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
RAM_RS42135	COG1960	acyl-CoA dehydrogenase activity
RAM_RS42150	COG0444	Belongs to the ABC transporter superfamily
RAM_RS42155	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RAM_RS42160	COG0601	transmembrane transport
RAM_RS42170	COG0747	negative chemotaxis
RAM_RS42200	COG3469	chitinase activity
RAM_RS42210	COG2814	Major facilitator Superfamily
RAM_RS42215	COG4336	lyase activity
RAM_RS42220	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
RAM_RS42225	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
RAM_RS42230	COG1984	allophanate hydrolase subunit 2
RAM_RS42270	COG1321	iron dependent repressor
RAM_RS42290	COG1024	Enoyl-CoA hydratase
RAM_RS42295	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_RS42320	COG1169	isochorismate synthase
RAM_RS42335	COG2182	Extracellular solute-binding protein
RAM_RS42340	COG1175	transmembrane transport
RAM_RS42345	COG0395	ABC-type sugar transport system, permease component
RAM_RS42370	COG1595	DNA-templated transcription, initiation
RAM_RS42385	COG0277	FAD linked oxidase domain protein
RAM_RS42410	COG4152	abc transporter atp-binding protein
RAM_RS42425	COG0415	Belongs to the DNA photolyase family
RAM_RS42445	COG1960	acyl-CoA dehydrogenase activity
RAM_RS42470	COG2017	converts alpha-aldose to the beta-anomer
RAM_RS42480	COG1309	transcriptional regulator
RAM_RS42505	COG0259	pyridoxamine-phosphate oxidase activity
RAM_RS42525	COG0829	nickel cation binding
RAM_RS42530	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
RAM_RS42540	COG0804	urea catabolic process
RAM_RS42545	COG0832	Belongs to the urease beta subunit family
RAM_RS42550	COG0831	urea catabolic process
RAM_RS42585	COG2197	response regulator
RAM_RS42590	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
RAM_RS42605	COG5650	phosphatidylinositol metabolic process
RAM_RS42610	COG1228	amidohydrolase
RAM_RS42615	COG0577	efflux transmembrane transporter activity
RAM_RS42615	COG1136	(ABC) transporter
RAM_RS42620	COG1136	(ABC) transporter
RAM_RS42620	COG0577	efflux transmembrane transporter activity
RAM_RS42635	COG0745	RESPONSE REGULATOR receiver
RAM_RS42640	COG2205	protein histidine kinase activity
RAM_RS42665	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RAM_RS42690	COG2162	N-hydroxyarylamine O-acetyltransferase activity
RAM_RS42695	COG2814	Major facilitator Superfamily
RAM_RS42710	COG2252	PERMEase
RAM_RS42735	COG2814	Major facilitator Superfamily
RAM_RS42745	COG1278	Cold shock
RAM_RS42765	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RAM_RS42770	COG0318	PFAM AMP-dependent synthetase and ligase
RAM_RS42780	COG1595	DNA-templated transcription, initiation
RAM_RS42790	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RAM_RS42830	COG0384	phenazine biosynthesis protein PhzF
RAM_RS42835	COG3304	Inner membrane component domain
RAM_RS42840	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
RAM_RS42875	COG1846	Transcriptional regulator
RAM_RS42890	COG1388	LysM domain
RAM_RS42935	COG2018	Roadblock/LC7 domain
RAM_RS42950	COG2018	Roadblock/LC7 domain
RAM_RS42955	COG0642	Histidine kinase
RAM_RS42960	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RAM_RS42965	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RAM_RS42970	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RAM_RS42975	COG1116	anion transmembrane transporter activity
RAM_RS43010	COG3142	Participates in the control of copper homeostasis
RAM_RS43030	COG1061	Type III restriction enzyme res subunit
RAM_RS43050	COG4948	Mandelate Racemase Muconate Lactonizing
RAM_RS43065	COG0459	protein refolding
RAM_RS43075	COG1278	Cold shock
RAM_RS43105	COG2261	transglycosylase associated protein
RAM_RS43110	COG0688	phosphatidylethanolamine metabolic process
RAM_RS43120	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RAM_RS43135	COG0242	peptide deformylase activity
RAM_RS43145	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RAM_RS43150	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
RAM_RS43155	COG0351	phosphomethylpyrimidine kinase
RAM_RS43175	COG2022	thiamine diphosphate biosynthetic process
RAM_RS43185	COG2022	thiamine diphosphate biosynthetic process
RAM_RS43185	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RAM_RS43190	COG0352	thiamine-phosphate diphosphorylase activity
RAM_RS43200	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
RAM_RS43205	COG0477	Major facilitator Superfamily
RAM_RS43215	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
RAM_RS43220	COG2971	BadF BadG BcrA BcrD
RAM_RS43230	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
RAM_RS43260	COG3629	intracellular signal transduction
RAM_RS43260	COG3903	Transcriptional regulator
RAM_RS43265	COG5285	phytanoyl-CoA dioxygenase
RAM_RS43270	COG1917	Cupin 2, conserved barrel domain protein
RAM_RS43285	COG1752	Esterase of the alpha-beta hydrolase superfamily
RAM_RS43295	COG1733	regulation of RNA biosynthetic process
RAM_RS43300	COG4399	Belongs to the UPF0754 family
RAM_RS43315	COG5416	Lipopolysaccharide assembly protein A domain
RAM_RS43410	COG3971	2-oxopent-4-enoate hydratase activity
RAM_RS43415	COG0346	lactoylglutathione lyase activity
RAM_RS43425	COG1832	CoA-binding protein
RAM_RS43470	COG0745	RESPONSE REGULATOR receiver
RAM_RS43475	COG2205	protein histidine kinase activity
RAM_RS43480	COG1492	cobalamin metabolic process
RAM_RS43485	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
RAM_RS43505	COG1620	l-lactate permease
RAM_RS43515	COG4941	Belongs to the sigma-70 factor family
RAM_RS43520	COG3795	YCII-related domain
RAM_RS43525	COG3795	YCII-related domain
RAM_RS43545	COG0642	Histidine kinase
RAM_RS43585	COG1595	DNA-templated transcription, initiation
RAM_RS43625	COG0789	Transcriptional regulator
RAM_RS43655	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
RAM_RS43690	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
RAM_RS43700	COG1329	Transcriptional regulator
RAM_RS43705	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
RAM_RS43710	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
RAM_RS43730	COG0215	cysteine-tRNA ligase activity
RAM_RS43770	COG0235	Class ii aldolase
RAM_RS43785	COG4399	Belongs to the UPF0754 family
RAM_RS43790	COG1108	ABC-type Mn2 Zn2 transport systems permease components
RAM_RS43795	COG1121	(ABC) transporter
RAM_RS43800	COG0803	Belongs to the bacterial solute-binding protein 9 family
RAM_RS43805	COG1609	Transcriptional regulator
RAM_RS43840	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RAM_RS43850	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
RAM_RS43925	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
RAM_RS43940	COG1396	sequence-specific DNA binding
RAM_RS43975	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
RAM_RS43985	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
RAM_RS43990	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
RAM_RS43995	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
RAM_RS44020	COG0789	Transcriptional regulator
RAM_RS44035	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
RAM_RS44040	COG0302	gtp cyclohydrolase
RAM_RS44045	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RAM_RS44075	COG0037	tRNA processing
RAM_RS44085	COG2027	D-alanyl-D-alanine carboxypeptidase
RAM_RS44090	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
RAM_RS44100	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
RAM_RS44105	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
RAM_RS44190	COG2188	Transcriptional regulator
RAM_RS44205	COG1674	ftsk spoiiie
RAM_RS44250	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
RAM_RS44255	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
RAM_RS44285	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
RAM_RS44285	COG1754	DNA topoisomerase type I activity
RAM_RS44305	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
RAM_RS44310	COG1111	helicase
RAM_RS44310	COG1205	dead DEAH box helicase
RAM_RS44355	COG1472	Belongs to the glycosyl hydrolase 3 family
RAM_RS44360	COG3876	Protein conserved in bacteria
RAM_RS44365	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
RAM_RS44370	COG1737	Transcriptional regulator
RAM_RS44375	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
RAM_RS44380	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
RAM_RS44390	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
RAM_RS44400	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RAM_RS44420	COG3104	oligopeptide transport
RAM_RS44425	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
RAM_RS44435	COG0596	Alpha beta hydrolase
RAM_RS44520	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RAM_RS44560	COG2894	cell division
RAM_RS44570	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
RAM_RS44580	COG1408	metallophosphoesterase
RAM_RS44590	COG2226	methyltransferase
RAM_RS44625	COG0463	Glycosyl transferase, family 2
RAM_RS44630	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
RAM_RS44640	COG2192	nodulation
RAM_RS44655	COG0076	glutamate decarboxylase activity
RAM_RS44660	COG0783	Belongs to the Dps family
RAM_RS44665	COG1764	response to oxidative stress
RAM_RS44675	COG0657	acetylesterase activity
RAM_RS44690	COG2814	Major facilitator Superfamily
RAM_RS44705	COG1690	Belongs to the RtcB family
RAM_RS44770	COG0583	DNA-binding transcription factor activity
RAM_RS44775	COG0697	spore germination
RAM_RS44790	COG3795	YCII-related domain
RAM_RS44795	COG4941	Belongs to the sigma-70 factor family
RAM_RS44800	COG4608	Belongs to the ABC transporter superfamily
RAM_RS44810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RAM_RS44815	COG0601	transmembrane transport
RAM_RS44820	COG0747	negative chemotaxis
RAM_RS44830	COG1216	Glycosyl transferase, family 2
RAM_RS44850	COG1215	transferase activity, transferring glycosyl groups
RAM_RS44860	COG1705	Flagellar rod assembly protein muramidase FlgJ
RAM_RS44865	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
RAM_RS44870	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
RAM_RS44880	COG1733	regulation of RNA biosynthetic process
RAM_RS44885	COG3467	pyridoxamine 5'-phosphate
RAM_RS44890	COG2801	Transposase and inactivated derivatives
RAM_RS44935	COG1116	anion transmembrane transporter activity
RAM_RS44940	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RAM_RS44950	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
RAM_RS44955	COG2205	protein histidine kinase activity
RAM_RS44960	COG0745	RESPONSE REGULATOR receiver
RAM_RS44975	COG2197	response regulator
RAM_RS44995	COG1250	3-hydroxyacyl-CoA dehydrogenase
RAM_RS45000	COG5479	isomerase activity
RAM_RS45000	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
RAM_RS45045	COG1674	ftsk spoiiie
RAM_RS45085	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
RAM_RS45090	COG2175	clavaminate synthase activity
RAM_RS45105	COG0702	epimerase
RAM_RS45130	COG1473	amidohydrolase
RAM_RS45145	COG4702	Belongs to the UPF0303 family
RAM_RS45155	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
RAM_RS45160	COG0789	Transcriptional regulator
RAM_RS45165	COG0395	ABC-type sugar transport system, permease component
RAM_RS45170	COG1175	transmembrane transport
RAM_RS45185	COG1802	Transcriptional regulator
RAM_RS45215	COG3973	AAA domain
RAM_RS45245	COG0673	inositol 2-dehydrogenase activity
RAM_RS45260	COG3345	alpha-galactosidase
RAM_RS45275	COG2188	Transcriptional regulator
RAM_RS45280	COG1397	ADP-ribosylglycohydrolase
RAM_RS45285	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RAM_RS45300	COG0596	Alpha beta hydrolase
RAM_RS45305	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
RAM_RS45320	COG1316	TRANSCRIPTIONal
RAM_RS45330	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
RAM_RS45335	COG0581	inorganic phosphate transmembrane transporter activity
RAM_RS45345	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
RAM_RS45355	COG0745	RESPONSE REGULATOR receiver
RAM_RS45385	COG4044	May play a role in the intracellular transport of hydrophobic ligands
RAM_RS45390	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
RAM_RS45395	COG1984	allophanate hydrolase subunit 2
RAM_RS45445	COG3845	ABC transporter
RAM_RS45480	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
RAM_RS45545	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
RAM_RS45555	COG1132	(ABC) transporter
RAM_RS45560	COG0047	phosphoribosylformylglycinamidine synthase activity
RAM_RS45565	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
RAM_RS45610	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
RAM_RS45620	COG1126	abc transporter atp-binding protein
RAM_RS45625	COG0765	amino acid transport
RAM_RS45635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RAM_RS45645	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
RAM_RS45650	COG4948	Mandelate Racemase Muconate Lactonizing
RAM_RS45665	COG2186	Transcriptional regulator
RAM_RS45690	COG0546	phosphoglycolate phosphatase activity
RAM_RS45705	COG0436	Aminotransferase
RAM_RS45710	COG5280	Phage tail tape measure protein TP901
RAM_RS45710	COG3953	SLT domain
RAM_RS45745	COG0584	glycerophosphoryl diester phosphodiesterase
RAM_RS45770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RAM_RS45780	COG2814	Major facilitator Superfamily
RAM_RS45785	COG0025	NhaP-type Na H and K H
RAM_RS45790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RAM_RS45800	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
RAM_RS45870	COG0667	Aldo Keto reductase
RAM_RS45875	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS45925	COG0586	Pfam SNARE associated Golgi protein
RAM_RS45940	COG0277	FAD linked oxidase domain protein
RAM_RS45945	COG3467	pyridoxamine 5'-phosphate
RAM_RS45965	COG0586	Pfam SNARE associated Golgi protein
RAM_RS45980	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS45985	COG0572	uridine kinase
RAM_RS45990	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RAM_RS46025	COG0243	molybdopterin cofactor binding
RAM_RS46070	COG1136	(ABC) transporter
RAM_RS46075	COG4221	oxidoreductase activity
RAM_RS46090	COG0542	response to heat
RAM_RS46115	COG0412	Dienelactone hydrolase
RAM_RS46130	COG0789	Transcriptional regulator
RAM_RS46135	COG0484	heat shock protein binding
RAM_RS46140	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
RAM_RS46145	COG0443	Heat shock 70 kDa protein
RAM_RS46180	COG2181	nitrate reductase activity
RAM_RS46180	COG0247	lactate metabolic process
RAM_RS46195	COG2340	Cysteine-rich secretory protein family
RAM_RS46235	COG4941	Belongs to the sigma-70 factor family
RAM_RS46240	COG3795	YCII-related domain
RAM_RS46245	COG2124	cytochrome p450
RAM_RS46290	COG3663	DNA glycosylase
RAM_RS46295	COG2197	response regulator
RAM_RS46300	COG1960	acyl-CoA dehydrogenase activity
RAM_RS46310	COG0477	Major facilitator Superfamily
RAM_RS46330	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
RAM_RS46355	COG1126	abc transporter atp-binding protein
RAM_RS46380	COG1305	Transglutaminase-like
RAM_RS46395	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RAM_RS46405	COG0022	dehydrogenase e1 component
RAM_RS46410	COG0508	dehydrogenase complex catalyzes the overall conversion of
RAM_RS46435	COG3030	protein affecting phage T7 exclusion by the F plasmid
RAM_RS46475	COG1309	transcriptional regulator
RAM_RS46480	COG2030	dehydratase
RAM_RS46485	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS46490	COG0183	Belongs to the thiolase family
RAM_RS46565	COG1131	(ABC) transporter
RAM_RS46580	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
RAM_RS46595	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
RAM_RS46610	COG4585	Histidine kinase
RAM_RS46615	COG2197	response regulator
RAM_RS46620	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS46640	COG1131	(ABC) transporter
RAM_RS46655	COG0220	tRNA (guanine-N7-)-methyltransferase activity
RAM_RS46665	COG1136	(ABC) transporter
RAM_RS46675	COG2197	response regulator
RAM_RS46690	COG0402	S-adenosylhomocysteine deaminase activity
RAM_RS46695	COG4221	oxidoreductase activity
RAM_RS46710	COG2814	Major facilitator Superfamily
RAM_RS46715	COG1846	Transcriptional regulator
RAM_RS46720	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RAM_RS46730	COG1595	DNA-templated transcription, initiation
RAM_RS46740	COG1695	Transcriptional regulator
RAM_RS46750	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RAM_RS46755	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RAM_RS46760	COG0673	inositol 2-dehydrogenase activity
RAM_RS46765	COG1940	carbohydrate kinase activity
RAM_RS46795	COG0360	Binds together with S18 to 16S ribosomal RNA
RAM_RS46805	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
RAM_RS46810	COG0359	binds to the 23S rRNA
RAM_RS46850	COG3384	dioxygenase
RAM_RS46875	COG2197	response regulator
RAM_RS46890	COG0477	Major facilitator Superfamily
RAM_RS46895	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
RAM_RS46905	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RAM_RS46960	COG1028	Short-chain dehydrogenase reductase Sdr
RAM_RS46965	COG0495	leucyl-tRNA aminoacylation
RAM_RS47045	COG0617	tRNA 3'-terminal CCA addition
RAM_RS47075	COG1595	DNA-templated transcription, initiation
RAM_RS47090	COG0492	ferredoxin-NADP+ reductase activity
RAM_RS47090	COG3118	belongs to the thioredoxin family
RAM_RS47095	COG0860	N-Acetylmuramoyl-L-alanine amidase
RAM_RS47095	COG3409	Peptidoglycan-binding domain 1 protein
RAM_RS47110	COG1181	Belongs to the D-alanine--D-alanine ligase family
RAM_RS47120	COG1192	Involved in chromosome partitioning
RAM_RS47125	COG0357	Ribosomal RNA small subunit methyltransferase G
RAM_RS47140	COG0706	membrane insertase activity
RAM_RS47145	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
RAM_RS47170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RAM_RS47180	COG2018	Roadblock/LC7 domain
RAM_RS47195	COG0535	radical SAM domain protein