locus-tag	class	description
AMES_RS00010	COG0592	DNA-directed DNA polymerase activity
AMES_RS00015	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AMES_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AMES_RS00025	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
AMES_RS00030	COG0187	DNA topoisomerase II activity
AMES_RS00180	COG0457	Tetratricopeptide repeat
AMES_RS00180	COG0705	Rhomboid family
AMES_RS00195	COG3764	Sortase (surface protein transpeptidase)
AMES_RS00225	COG2197	response regulator
AMES_RS00255	COG2815	serine threonine protein kinase
AMES_RS00255	COG0515	serine threonine protein kinase
AMES_RS00260	COG0515	serine threonine protein kinase
AMES_RS00265	COG0768	penicillin binding
AMES_RS00280	COG1716	ATPase activity
AMES_RS00285	COG1716	ATPase activity
AMES_RS00315	COG0626	cystathionine gamma-synthase activity
AMES_RS00335	COG2186	Transcriptional regulator
AMES_RS00340	COG0747	negative chemotaxis
AMES_RS00350	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AMES_RS00355	COG0444	Belongs to the ABC transporter superfamily
AMES_RS00360	COG4608	Belongs to the ABC transporter superfamily
AMES_RS00365	COG1012	belongs to the aldehyde dehydrogenase family
AMES_RS00370	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS00375	COG0154	amidase activity
AMES_RS00380	COG3547	Transposase (IS116 IS110 IS902 family)
AMES_RS00400	COG2301	Belongs to the HpcH HpaI aldolase family
AMES_RS00410	COG0702	epimerase
AMES_RS00415	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AMES_RS00430	COG1309	transcriptional regulator
AMES_RS00440	COG2211	Major facilitator Superfamily
AMES_RS00470	COG1276	copper resistance
AMES_RS00470	COG2372	response to copper ion
AMES_RS00485	COG1174	glycine betaine transport
AMES_RS00495	COG1174	glycine betaine transport
AMES_RS00520	COG2226	methyltransferase
AMES_RS00530	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AMES_RS00535	COG0405	Gamma-glutamyltransferase
AMES_RS00545	COG5433	transposase activity
AMES_RS00560	COG0477	Major facilitator Superfamily
AMES_RS00570	COG4585	Histidine kinase
AMES_RS00575	COG2197	response regulator
AMES_RS00605	COG0438	transferase activity, transferring glycosyl groups
AMES_RS00660	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AMES_RS00665	COG3275	phosphorelay sensor kinase activity
AMES_RS00690	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AMES_RS00695	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AMES_RS00695	COG0425	Belongs to the sulfur carrier protein TusA family
AMES_RS00715	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AMES_RS00735	COG1191	sigma factor activity
AMES_RS00825	COG1271	oxidase subunit
AMES_RS00830	COG1294	oxidase, subunit
AMES_RS00835	COG4988	ABC transporter
AMES_RS00890	COG4715	Zinc finger, swim domain protein
AMES_RS00900	COG1072	(Pantothenic acid kinase))
AMES_RS00905	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AMES_RS00915	COG0406	alpha-ribazole phosphatase activity
AMES_RS00950	COG0754	glutathionylspermidine amidase activity
AMES_RS00960	COG0596	Alpha beta hydrolase
AMES_RS00965	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AMES_RS00970	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AMES_RS00980	COG0579	oxidoreductase
AMES_RS01005	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AMES_RS01020	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AMES_RS01050	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AMES_RS01060	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS01065	COG0318	PFAM AMP-dependent synthetase and ligase
AMES_RS01110	COG0561	phosphatase activity
AMES_RS01115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMES_RS01135	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AMES_RS01150	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS01155	COG0277	FAD linked oxidase domain protein
AMES_RS01165	COG1216	Glycosyl transferase, family 2
AMES_RS01195	COG1216	Glycosyl transferase, family 2
AMES_RS01220	COG0604	alcohol dehydrogenase
AMES_RS01220	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS01220	COG3321	synthase
AMES_RS01225	COG2234	aminopeptidase activity
AMES_RS01285	COG4565	transcriptional regulatory protein
AMES_RS01290	COG3290	protein histidine kinase activity
AMES_RS01295	COG1116	anion transmembrane transporter activity
AMES_RS01320	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AMES_RS01320	COG1672	PFAM Archaeal ATPase
AMES_RS01335	COG1522	sequence-specific DNA binding
AMES_RS01340	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AMES_RS01350	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AMES_RS01355	COG2186	Transcriptional regulator
AMES_RS01370	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AMES_RS01380	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AMES_RS01410	COG3469	chitinase activity
AMES_RS01415	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AMES_RS01440	COG3584	3D domain protein
AMES_RS01440	COG3583	domain protein
AMES_RS01515	COG3559	Exporter of polyketide antibiotics
AMES_RS01520	COG1131	(ABC) transporter
AMES_RS01575	COG0287	Prephenate dehydrogenase
AMES_RS01580	COG0446	pyridine nucleotide-disulphide oxidoreductase
AMES_RS01580	COG1902	pentaerythritol trinitrate reductase activity
AMES_RS01600	COG1846	Transcriptional regulator
AMES_RS01630	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AMES_RS01640	COG2318	DinB family
AMES_RS01650	COG0194	GDP metabolic process
AMES_RS01710	COG0515	serine threonine protein kinase
AMES_RS01725	COG0028	Belongs to the TPP enzyme family
AMES_RS01740	COG3199	ATP-NAD kinase
AMES_RS01745	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AMES_RS01760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMES_RS01765	COG0515	serine threonine protein kinase
AMES_RS01775	COG0477	Major facilitator Superfamily
AMES_RS01785	COG1595	DNA-templated transcription, initiation
AMES_RS01800	COG1278	Cold shock
AMES_RS01975	COG2226	methyltransferase
AMES_RS02015	COG2233	PERMEase
AMES_RS02020	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AMES_RS02030	COG1414	Transcriptional regulator
AMES_RS02050	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
AMES_RS02140	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AMES_RS02165	COG2364	Membrane
AMES_RS02170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AMES_RS02185	COG2733	membrane
AMES_RS02205	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AMES_RS02240	COG2986	histidine ammonia-lyase
AMES_RS02270	COG1174	glycine betaine transport
AMES_RS02285	COG1846	Transcriptional regulator
AMES_RS02295	COG2130	NADP-dependent
AMES_RS02310	COG1064	alcohol dehydrogenase
AMES_RS02340	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AMES_RS02355	COG0438	transferase activity, transferring glycosyl groups
AMES_RS02370	COG0588	phosphoglycerate mutase activity
AMES_RS02380	COG0667	Aldo Keto reductase
AMES_RS02385	COG5002	protein histidine kinase activity
AMES_RS02415	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AMES_RS02435	COG4585	Histidine kinase
AMES_RS02460	COG1595	DNA-templated transcription, initiation
AMES_RS02465	COG0318	PFAM AMP-dependent synthetase and ligase
AMES_RS02480	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
AMES_RS02485	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AMES_RS02490	COG0181	hydroxymethylbilane synthase activity
AMES_RS02495	COG1648	precorrin-2 dehydrogenase activity
AMES_RS02495	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AMES_RS02530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMES_RS02535	COG1136	(ABC) transporter
AMES_RS02535	COG0577	efflux transmembrane transporter activity
AMES_RS02540	COG0577	efflux transmembrane transporter activity
AMES_RS02540	COG1136	(ABC) transporter
AMES_RS02555	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AMES_RS02560	COG0406	alpha-ribazole phosphatase activity
AMES_RS02565	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AMES_RS02570	COG0785	Cytochrome C biogenesis protein
AMES_RS02580	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AMES_RS02600	COG1522	sequence-specific DNA binding
AMES_RS02630	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AMES_RS02655	COG0438	transferase activity, transferring glycosyl groups
AMES_RS02670	COG2226	methyltransferase
AMES_RS02685	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMES_RS02690	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMES_RS02695	COG0649	NAD binding
AMES_RS02710	COG1034	ATP synthesis coupled electron transport
AMES_RS02715	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AMES_RS02720	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMES_RS02725	COG0839	Belongs to the complex I subunit 6 family
AMES_RS02730	COG0713	ATP synthesis coupled electron transport
AMES_RS02735	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AMES_RS02745	COG1007	ATP synthesis coupled electron transport
AMES_RS02775	COG0142	geranyltranstransferase activity
AMES_RS02790	COG1013	pyruvate-flavodoxin oxidoreductase activity
AMES_RS02795	COG0674	pyruvate-flavodoxin oxidoreductase activity
AMES_RS02795	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AMES_RS02805	COG1522	sequence-specific DNA binding
AMES_RS02810	COG1834	amidinotransferase
AMES_RS02825	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AMES_RS02830	COG0438	transferase activity, transferring glycosyl groups
AMES_RS02845	COG0367	asparagine synthase
AMES_RS02890	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AMES_RS02895	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
AMES_RS02905	COG1215	transferase activity, transferring glycosyl groups
AMES_RS02915	COG4310	Domain of unknown function (DUF2172)
AMES_RS02930	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AMES_RS02945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMES_RS02960	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMES_RS02965	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMES_RS02985	COG1666	GTP binding
AMES_RS03005	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AMES_RS03035	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AMES_RS03040	COG2030	dehydratase
AMES_RS03060	COG1725	Transcriptional regulator
AMES_RS03090	COG0081	regulation of translation
AMES_RS03095	COG2267	carboxylic ester hydrolase activity
AMES_RS03125	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AMES_RS03150	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AMES_RS03175	COG0673	inositol 2-dehydrogenase activity
AMES_RS03195	COG0604	alcohol dehydrogenase
AMES_RS03195	COG3321	synthase
AMES_RS03215	COG0604	alcohol dehydrogenase
AMES_RS03215	COG3321	synthase
AMES_RS03235	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AMES_RS03240	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AMES_RS03255	COG0546	phosphoglycolate phosphatase activity
AMES_RS03265	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AMES_RS03270	COG0657	acetylesterase activity
AMES_RS03275	COG0477	Major facilitator Superfamily
AMES_RS03290	COG2124	cytochrome p450
AMES_RS03295	COG2124	cytochrome p450
AMES_RS03315	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AMES_RS03330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMES_RS03355	COG2124	cytochrome p450
AMES_RS03365	COG3959	Transketolase, thiamine diphosphate binding domain
AMES_RS03370	COG3958	Transketolase
AMES_RS03380	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AMES_RS03395	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AMES_RS03405	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
AMES_RS03410	COG1522	sequence-specific DNA binding
AMES_RS03415	COG0477	Major facilitator Superfamily
AMES_RS03425	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AMES_RS03425	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AMES_RS03470	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AMES_RS03475	COG0049	tRNA binding
AMES_RS03480	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AMES_RS03490	COG0051	transcription antitermination factor activity, RNA binding
AMES_RS03495	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AMES_RS03500	COG0088	Forms part of the polypeptide exit tunnel
AMES_RS03505	COG0089	rRNA binding
AMES_RS03510	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AMES_RS03515	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AMES_RS03520	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AMES_RS03525	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AMES_RS03530	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AMES_RS03535	COG0255	Belongs to the universal ribosomal protein uL29 family
AMES_RS03540	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AMES_RS03545	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AMES_RS03550	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AMES_RS03555	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AMES_RS03565	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AMES_RS03570	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AMES_RS03575	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AMES_RS03580	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AMES_RS03585	COG1841	ribosomal large subunit assembly
AMES_RS03590	COG0200	Binds to the 23S rRNA
AMES_RS03600	COG1280	lysine exporter protein (LysE YggA)
AMES_RS03610	COG0563	adenylate kinase activity
AMES_RS03620	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AMES_RS03625	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AMES_RS03640	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AMES_RS03645	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AMES_RS03650	COG0202	RNA polymerase activity
AMES_RS03655	COG0203	ribosomal protein L17
AMES_RS03660	COG0101	tRNA pseudouridine synthase activity
AMES_RS03695	COG1404	Belongs to the peptidase S8 family
AMES_RS03705	COG1674	ftsk spoiiie
AMES_RS03710	COG0443	Heat shock 70 kDa protein
AMES_RS03740	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AMES_RS03745	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AMES_RS03750	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AMES_RS03760	COG0318	PFAM AMP-dependent synthetase and ligase
AMES_RS03800	COG1349	DNA-binding transcription factor activity
AMES_RS03805	COG1070	Carbohydrate kinase
AMES_RS03810	COG3842	ATPase activity
AMES_RS03815	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AMES_RS03825	COG0802	atpase or kinase
AMES_RS03835	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AMES_RS03835	COG0825	malonyl-CoA metabolic process
AMES_RS03840	COG0318	PFAM AMP-dependent synthetase and ligase
AMES_RS03850	COG0456	acetyltransferase
AMES_RS03855	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AMES_RS03860	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AMES_RS03880	COG1215	transferase activity, transferring glycosyl groups
AMES_RS03890	COG2226	methyltransferase
AMES_RS03900	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AMES_RS03905	COG0798	PFAM Bile acid sodium symporter
AMES_RS03910	COG0640	Transcriptional regulator
AMES_RS03920	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AMES_RS03925	COG0459	protein refolding
AMES_RS03975	COG0516	GMP reductase activity
AMES_RS03995	COG0277	FAD linked oxidase domain protein
AMES_RS04000	COG1012	belongs to the aldehyde dehydrogenase family
AMES_RS04020	COG0519	Catalyzes the synthesis of GMP from XMP
AMES_RS04020	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AMES_RS04035	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS04055	COG0697	spore germination
AMES_RS04060	COG0583	DNA-binding transcription factor activity
AMES_RS04070	COG2815	serine threonine protein kinase
AMES_RS04070	COG0515	serine threonine protein kinase
AMES_RS04120	COG0045	succinate-CoA ligase (ADP-forming) activity
AMES_RS04145	COG0138	bifunctional purine biosynthesis protein purh
AMES_RS04185	COG0587	DNA-directed DNA polymerase activity
AMES_RS04205	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AMES_RS04215	COG2814	Major facilitator Superfamily
AMES_RS04220	COG0640	Transcriptional regulator
AMES_RS04225	COG2814	Major facilitator Superfamily
AMES_RS04235	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AMES_RS04260	COG2226	methyltransferase
AMES_RS04295	COG1234	tRNA 3'-trailer cleavage
AMES_RS04310	COG0180	Tryptophanyl-tRNA synthetase
AMES_RS04320	COG1295	ribonuclease BN
AMES_RS04335	COG1686	Belongs to the peptidase S11 family
AMES_RS04355	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AMES_RS04370	COG2009	succinate dehydrogenase
AMES_RS04375	COG3345	alpha-galactosidase
AMES_RS04380	COG1082	Xylose isomerase domain protein TIM barrel
AMES_RS04385	COG1744	ABC transporter substrate-binding protein PnrA-like
AMES_RS04390	COG3845	ABC transporter
AMES_RS04400	COG1079	Belongs to the binding-protein-dependent transport system permease family
AMES_RS04420	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AMES_RS04425	COG2271	Major facilitator Superfamily
AMES_RS04445	COG1733	regulation of RNA biosynthetic process
AMES_RS04455	COG1063	alcohol dehydrogenase
AMES_RS04470	COG0395	ABC-type sugar transport system, permease component
AMES_RS04505	COG1012	belongs to the aldehyde dehydrogenase family
AMES_RS04510	COG1012	belongs to the aldehyde dehydrogenase family
AMES_RS04515	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AMES_RS04555	COG0789	Transcriptional regulator
AMES_RS04560	COG0667	Aldo Keto reductase
AMES_RS04580	COG0475	glutathione-regulated potassium exporter activity
AMES_RS04585	COG0745	RESPONSE REGULATOR receiver
AMES_RS04590	COG2205	protein histidine kinase activity
AMES_RS04610	COG0402	S-adenosylhomocysteine deaminase activity
AMES_RS04635	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AMES_RS04665	COG0515	serine threonine protein kinase
AMES_RS04690	COG1473	amidohydrolase
AMES_RS04690	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AMES_RS04730	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AMES_RS04735	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AMES_RS04740	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AMES_RS04775	COG4770	biotin carboxylase activity
AMES_RS04790	COG1301	dicarboxylic acid transport
AMES_RS04795	COG0424	maF-like protein
AMES_RS04800	COG1472	Belongs to the glycosyl hydrolase 3 family
AMES_RS04820	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMES_RS04825	COG1846	Transcriptional regulator
AMES_RS04835	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AMES_RS04850	COG4585	Histidine kinase
AMES_RS04870	COG1309	transcriptional regulator
AMES_RS04880	COG1733	regulation of RNA biosynthetic process
AMES_RS04890	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS04905	COG0583	DNA-binding transcription factor activity
AMES_RS04920	COG2226	methyltransferase
AMES_RS04935	COG1902	pentaerythritol trinitrate reductase activity
AMES_RS04935	COG0446	pyridine nucleotide-disulphide oxidoreductase
AMES_RS04955	COG4585	Histidine kinase
AMES_RS04960	COG2197	response regulator
AMES_RS04965	COG0791	NLP P60 protein
AMES_RS04965	COG1388	LysM domain
AMES_RS04965	COG3103	Sh3 type 3 domain protein
AMES_RS04980	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AMES_RS04995	COG3537	Alpha-1,2-mannosidase
AMES_RS05000	COG0483	inositol monophosphate 1-phosphatase activity
AMES_RS05010	COG2205	protein histidine kinase activity
AMES_RS05015	COG2197	response regulator
AMES_RS05020	COG2197	response regulator
AMES_RS05085	COG0318	PFAM AMP-dependent synthetase and ligase
AMES_RS05125	COG0702	epimerase
AMES_RS05130	COG1316	TRANSCRIPTIONal
AMES_RS05135	COG1316	TRANSCRIPTIONal
AMES_RS05165	COG0438	transferase activity, transferring glycosyl groups
AMES_RS05200	COG1725	Transcriptional regulator
AMES_RS05215	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
AMES_RS05215	COG0778	Nitroreductase
AMES_RS05220	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AMES_RS05310	COG1611	Belongs to the LOG family
AMES_RS05325	COG1216	Glycosyl transferase, family 2
AMES_RS05350	COG0463	Glycosyl transferase, family 2
AMES_RS05355	COG1132	(ABC) transporter
AMES_RS05360	COG4988	ABC transporter
AMES_RS05365	COG1294	oxidase, subunit
AMES_RS05370	COG1271	oxidase subunit
AMES_RS05395	COG2818	Glycosylase
AMES_RS05400	COG1024	Enoyl-CoA hydratase
AMES_RS05410	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AMES_RS05415	COG0583	DNA-binding transcription factor activity
AMES_RS05420	COG2814	Major facilitator Superfamily
AMES_RS05430	COG4122	O-methyltransferase activity
AMES_RS05435	COG1595	DNA-templated transcription, initiation
AMES_RS05445	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AMES_RS05450	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AMES_RS05465	COG2239	Acts as a magnesium transporter
AMES_RS05475	COG0330	HflC and HflK could
AMES_RS05525	COG1309	transcriptional regulator
AMES_RS05535	COG2197	response regulator
AMES_RS05540	COG4585	Histidine kinase
AMES_RS05570	COG0598	Magnesium transport protein CorA
AMES_RS05600	COG0613	PHP domain protein
AMES_RS05605	COG2095	MarC family integral membrane protein
AMES_RS05630	COG0513	Belongs to the DEAD box helicase family
AMES_RS05660	COG2267	carboxylic ester hydrolase activity
AMES_RS05665	COG1309	transcriptional regulator
AMES_RS05670	COG2267	carboxylic ester hydrolase activity
AMES_RS05690	COG0243	molybdopterin cofactor binding
AMES_RS05695	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AMES_RS05705	COG2146	nitrite reductase [NAD(P)H] activity
AMES_RS05705	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AMES_RS05710	COG2146	nitrite reductase [NAD(P)H] activity
AMES_RS05710	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AMES_RS05735	COG2378	regulation of single-species biofilm formation
AMES_RS05795	COG0714	Associated with various cellular activities
AMES_RS05820	COG2321	neutral zinc metallopeptidase
AMES_RS05840	COG0612	Peptidase, M16
AMES_RS05860	COG1175	transmembrane transport
AMES_RS05865	COG0395	ABC-type sugar transport system, permease component
AMES_RS05870	COG1486	melibiose metabolic process
AMES_RS05885	COG0640	Transcriptional regulator
AMES_RS05900	COG3265	gluconokinase activity
AMES_RS05910	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AMES_RS05945	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AMES_RS05965	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AMES_RS06055	COG1012	belongs to the aldehyde dehydrogenase family
AMES_RS06085	COG1012	belongs to the aldehyde dehydrogenase family
AMES_RS06090	COG3842	ATPase activity
AMES_RS06095	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AMES_RS06100	COG1176	ABC-type spermidine putrescine transport system, permease component I
AMES_RS06105	COG1177	transmembrane transport
AMES_RS06110	COG0596	Alpha beta hydrolase
AMES_RS06115	COG1968	undecaprenyl-diphosphatase activity
AMES_RS06125	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AMES_RS06130	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AMES_RS06130	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AMES_RS06140	COG2318	DinB family
AMES_RS06155	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AMES_RS06155	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AMES_RS06160	COG0653	protein targeting
AMES_RS06180	COG0174	glutamine synthetase
AMES_RS06185	COG0154	amidase activity
AMES_RS06205	COG1522	sequence-specific DNA binding
AMES_RS06215	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AMES_RS06215	COG0519	Catalyzes the synthesis of GMP from XMP
AMES_RS06225	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AMES_RS06235	COG0174	glutamine synthetase
AMES_RS06295	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AMES_RS06315	COG3480	Lon protease (S16) C-terminal proteolytic domain
AMES_RS06325	COG1615	UPF0182 protein
AMES_RS06355	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AMES_RS06360	COG2884	Cell division ATP-binding protein ftsE
AMES_RS06365	COG2177	Part of the ABC transporter FtsEX involved in
AMES_RS06370	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AMES_RS06395	COG2197	response regulator
AMES_RS06400	COG4585	Histidine kinase
AMES_RS06410	COG3706	GGDEF domain
AMES_RS06425	COG2986	histidine ammonia-lyase
AMES_RS06430	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AMES_RS06440	COG0402	S-adenosylhomocysteine deaminase activity
AMES_RS06445	COG1228	amidohydrolase
AMES_RS06450	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AMES_RS06485	COG4585	Histidine kinase
AMES_RS06515	COG1131	(ABC) transporter
AMES_RS06520	COG1643	Atp-dependent helicase
AMES_RS06525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMES_RS06545	COG3883	PFAM NLP P60 protein
AMES_RS06545	COG0791	NLP P60 protein
AMES_RS06560	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AMES_RS06570	COG2318	DinB family
AMES_RS06575	COG1472	Belongs to the glycosyl hydrolase 3 family
AMES_RS06585	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AMES_RS06590	COG0187	DNA topoisomerase II activity
AMES_RS06635	COG1172	Belongs to the binding-protein-dependent transport system permease family
AMES_RS06640	COG1172	Belongs to the binding-protein-dependent transport system permease family
AMES_RS06645	COG1129	ABC transporter
AMES_RS06650	COG1879	ABC-type sugar transport system periplasmic component
AMES_RS06655	COG1609	Transcriptional regulator
AMES_RS06660	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AMES_RS06670	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS06690	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AMES_RS06720	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AMES_RS06750	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS06760	COG0017	Asparaginyl-tRNA synthetase
AMES_RS06780	COG0596	Alpha beta hydrolase
AMES_RS06805	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AMES_RS06810	COG1486	melibiose metabolic process
AMES_RS06820	COG1053	succinate dehydrogenase
AMES_RS06825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMES_RS06830	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AMES_RS06840	COG0596	Alpha beta hydrolase
AMES_RS06930	COG0697	spore germination
AMES_RS06935	COG1846	Transcriptional regulator
AMES_RS06970	COG3903	Transcriptional regulator
AMES_RS06970	COG3629	intracellular signal transduction
AMES_RS06980	COG2211	Major facilitator Superfamily
AMES_RS06990	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AMES_RS06995	COG0411	ABC transporter
AMES_RS07020	COG1309	transcriptional regulator
AMES_RS07050	COG1136	(ABC) transporter
AMES_RS07105	COG0477	Major facilitator Superfamily
AMES_RS07120	COG3387	PFAM Glycoside hydrolase 15-related
AMES_RS07125	COG1063	alcohol dehydrogenase
AMES_RS07145	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMES_RS07195	COG3209	COG3209 Rhs family protein
AMES_RS07230	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS07230	COG0604	alcohol dehydrogenase
AMES_RS07230	COG3321	synthase
AMES_RS07260	COG2018	Roadblock/LC7 domain
AMES_RS07285	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS07290	COG0583	DNA-binding transcription factor activity
AMES_RS07295	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS07340	COG0667	Aldo Keto reductase
AMES_RS07350	COG1595	DNA-templated transcription, initiation
AMES_RS07380	COG3903	Transcriptional regulator
AMES_RS07380	COG3629	intracellular signal transduction
AMES_RS07390	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
AMES_RS07405	COG0604	alcohol dehydrogenase
AMES_RS07420	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AMES_RS07425	COG0318	PFAM AMP-dependent synthetase and ligase
AMES_RS07470	COG1234	tRNA 3'-trailer cleavage
AMES_RS07480	COG3852	Histidine kinase
AMES_RS07485	COG2272	Belongs to the type-B carboxylesterase lipase family
AMES_RS07525	COG3547	Transposase (IS116 IS110 IS902 family)
AMES_RS07535	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AMES_RS07615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMES_RS07620	COG0765	amino acid transport
AMES_RS07625	COG1126	abc transporter atp-binding protein
AMES_RS07630	COG2964	Protein conserved in bacteria
AMES_RS07650	COG1131	(ABC) transporter
AMES_RS07680	COG2186	Transcriptional regulator
AMES_RS07685	COG1172	Belongs to the binding-protein-dependent transport system permease family
AMES_RS07690	COG1129	ABC transporter
AMES_RS07710	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AMES_RS07710	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AMES_RS07715	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AMES_RS07730	COG1879	ABC-type sugar transport system periplasmic component
AMES_RS07750	COG3903	Transcriptional regulator
AMES_RS07750	COG3629	intracellular signal transduction
AMES_RS07760	COG3540	Alkaline phosphatase
AMES_RS07770	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
AMES_RS07780	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
AMES_RS07785	COG1940	carbohydrate kinase activity
AMES_RS07805	COG4221	oxidoreductase activity
AMES_RS07810	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AMES_RS07830	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AMES_RS07845	COG0513	Belongs to the DEAD box helicase family
AMES_RS07870	COG2183	response to ionizing radiation
AMES_RS07915	COG1309	transcriptional regulator
AMES_RS07930	COG1012	belongs to the aldehyde dehydrogenase family
AMES_RS07930	COG2030	dehydratase
AMES_RS07935	COG3396	Phenylacetate-CoA oxygenase
AMES_RS07940	COG3460	Phenylacetate-CoA oxygenase
AMES_RS07945	COG3396	Phenylacetate-CoA oxygenase
AMES_RS07950	COG2151	metal-sulfur cluster biosynthetic enzyme
AMES_RS07955	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AMES_RS07970	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AMES_RS07985	COG0604	alcohol dehydrogenase
AMES_RS08000	COG0346	lactoylglutathione lyase activity
AMES_RS08005	COG0183	Belongs to the thiolase family
AMES_RS08020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AMES_RS08025	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AMES_RS08030	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AMES_RS08035	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AMES_RS08045	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AMES_RS08055	COG3279	Response regulator of the LytR AlgR family
AMES_RS08060	COG3275	phosphorelay sensor kinase activity
AMES_RS08070	COG1879	ABC-type sugar transport system periplasmic component
AMES_RS08075	COG1172	Belongs to the binding-protein-dependent transport system permease family
AMES_RS08090	COG1609	Transcriptional regulator
AMES_RS08095	COG3537	Alpha-1,2-mannosidase
AMES_RS08100	COG3537	Alpha-1,2-mannosidase
AMES_RS08110	COG1846	Transcriptional regulator
AMES_RS08135	COG0058	SHG alpha-glucan phosphorylase activity
AMES_RS08160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMES_RS08175	COG1119	ATPase activity
AMES_RS08180	COG1024	Enoyl-CoA hydratase
AMES_RS08185	COG2226	methyltransferase
AMES_RS08205	COG3979	chitinase
AMES_RS08215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AMES_RS08250	COG0667	Aldo Keto reductase
AMES_RS08255	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AMES_RS08260	COG3883	PFAM NLP P60 protein
AMES_RS08260	COG0791	NLP P60 protein
AMES_RS08265	COG1957	nucleoside hydrolase
AMES_RS08270	COG0110	maltose O-acetyltransferase activity
AMES_RS08310	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AMES_RS08345	COG3250	beta-galactosidase activity
AMES_RS08350	COG0386	Belongs to the glutathione peroxidase family
AMES_RS08360	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AMES_RS08370	COG1307	EDD domain protein, DegV family
AMES_RS08380	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AMES_RS08395	COG0604	alcohol dehydrogenase
AMES_RS08400	COG2197	response regulator
AMES_RS08415	COG0482	sulfurtransferase activity
AMES_RS08435	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AMES_RS08455	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AMES_RS08470	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AMES_RS08475	COG0154	amidase activity
AMES_RS08480	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AMES_RS08505	COG0673	inositol 2-dehydrogenase activity
AMES_RS08515	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AMES_RS08525	COG0129	dihydroxy-acid dehydratase activity
AMES_RS08540	COG0440	acetolactate synthase activity
AMES_RS08545	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AMES_RS08585	COG1404	Belongs to the peptidase S8 family
AMES_RS08590	COG0473	3-isopropylmalate dehydrogenase activity
AMES_RS08595	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AMES_RS08600	COG0179	Fumarylacetoacetate (FAA) hydrolase
AMES_RS08630	COG3629	intracellular signal transduction
AMES_RS08630	COG3903	Transcriptional regulator
AMES_RS08685	COG0776	regulation of translation
AMES_RS08695	COG0420	3'-5' exonuclease activity
AMES_RS08700	COG0419	ATPase involved in DNA repair
AMES_RS08710	COG1472	Belongs to the glycosyl hydrolase 3 family
AMES_RS08735	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AMES_RS08740	COG0066	3-isopropylmalate dehydratase activity
AMES_RS08750	COG3629	intracellular signal transduction
AMES_RS08750	COG3903	Transcriptional regulator
AMES_RS08765	COG1920	GTP binding
AMES_RS08775	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AMES_RS08785	COG0252	asparaginase activity
AMES_RS08795	COG1477	protein flavinylation
AMES_RS08810	COG0745	RESPONSE REGULATOR receiver
AMES_RS08815	COG2205	protein histidine kinase activity
AMES_RS08825	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AMES_RS08855	COG3345	alpha-galactosidase
AMES_RS08860	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AMES_RS08865	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AMES_RS08875	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AMES_RS08880	COG1461	Dihydroxyacetone kinase
AMES_RS08910	COG1404	Belongs to the peptidase S8 family
AMES_RS08915	COG5433	transposase activity
AMES_RS08995	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AMES_RS09020	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AMES_RS09030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMES_RS09035	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AMES_RS09045	COG0542	response to heat
AMES_RS09050	COG2319	Wd-40 repeat
AMES_RS09050	COG4249	Peptidase C14 caspase catalytic subunit p20
AMES_RS09055	COG3973	AAA domain
AMES_RS09060	COG0742	ribosomal rna small subunit methyltransferase
AMES_RS09065	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AMES_RS09095	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AMES_RS09100	COG0571	ribonuclease III activity
AMES_RS09110	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AMES_RS09130	COG3386	PFAM SMP-30 Gluconolaconase
AMES_RS09160	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AMES_RS09165	COG1012	belongs to the aldehyde dehydrogenase family
AMES_RS09185	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AMES_RS09185	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AMES_RS09190	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AMES_RS09195	COG0509	glycine decarboxylation via glycine cleavage system
AMES_RS09200	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AMES_RS09205	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AMES_RS09210	COG1760	l-serine dehydratase
AMES_RS09220	COG2442	InterPro IPR007367
AMES_RS09230	COG2186	Transcriptional regulator
AMES_RS09240	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AMES_RS09245	COG4122	O-methyltransferase activity
AMES_RS09250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AMES_RS09280	COG0789	Transcriptional regulator
AMES_RS09290	COG2814	Major facilitator Superfamily
AMES_RS09295	COG0179	Fumarylacetoacetate (FAA) hydrolase
AMES_RS09300	COG4948	Mandelate Racemase Muconate Lactonizing
AMES_RS09305	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS09310	COG1879	ABC-type sugar transport system periplasmic component
AMES_RS09315	COG1129	ABC transporter
AMES_RS09320	COG1172	Belongs to the binding-protein-dependent transport system permease family
AMES_RS09325	COG2186	Transcriptional regulator
AMES_RS09370	COG1929	Belongs to the glycerate kinase type-1 family
AMES_RS09375	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AMES_RS09385	COG1940	carbohydrate kinase activity
AMES_RS09390	COG1653	transport
AMES_RS09400	COG0395	ABC-type sugar transport system, permease component
AMES_RS09405	COG3345	alpha-galactosidase
AMES_RS09410	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AMES_RS09415	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AMES_RS09420	COG0183	Belongs to the thiolase family
AMES_RS09425	COG3485	protocatechuate 3,4-dioxygenase
AMES_RS09430	COG3485	protocatechuate 3,4-dioxygenase
AMES_RS09435	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AMES_RS09445	COG1414	Transcriptional regulator
AMES_RS09450	COG0746	molybdenum cofactor guanylyltransferase activity
AMES_RS09455	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AMES_RS09495	COG3706	GGDEF domain
AMES_RS09505	COG0667	Aldo Keto reductase
AMES_RS09530	COG3962	Belongs to the TPP enzyme family
AMES_RS09535	COG3718	enzyme involved in inositol metabolism
AMES_RS09545	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AMES_RS09565	COG1082	Xylose isomerase domain protein TIM barrel
AMES_RS09570	COG1609	Transcriptional regulator
AMES_RS09575	COG0673	inositol 2-dehydrogenase activity
AMES_RS09580	COG0367	asparagine synthase
AMES_RS09590	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AMES_RS09595	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AMES_RS09600	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AMES_RS09635	COG1254	Belongs to the acylphosphatase family
AMES_RS09650	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AMES_RS09655	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AMES_RS09675	COG1414	Transcriptional regulator
AMES_RS09680	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AMES_RS09715	COG3835	regulator
AMES_RS09735	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AMES_RS09740	COG3345	alpha-galactosidase
AMES_RS09745	COG1309	transcriptional regulator
AMES_RS09775	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AMES_RS09780	COG4266	Belongs to the allantoicase family
AMES_RS09785	COG1832	CoA-binding protein
AMES_RS09790	COG2873	o-acetylhomoserine
AMES_RS09810	COG1595	DNA-templated transcription, initiation
AMES_RS09835	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AMES_RS09855	COG3706	GGDEF domain
AMES_RS09860	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS09865	COG1309	transcriptional regulator
AMES_RS09875	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
AMES_RS09885	COG1132	(ABC) transporter
AMES_RS09910	COG0228	four-way junction DNA binding
AMES_RS09930	COG0336	Belongs to the RNA methyltransferase TrmD family
AMES_RS09935	COG0335	large ribosomal subunit rRNA binding
AMES_RS09940	COG0681	Belongs to the peptidase S26 family
AMES_RS09945	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AMES_RS09955	COG0792	nuclease activity
AMES_RS09980	COG1191	sigma factor activity
AMES_RS09990	COG0052	Belongs to the universal ribosomal protein uS2 family
AMES_RS09995	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AMES_RS10000	COG0528	UMP kinase activity
AMES_RS10005	COG0233	cytoplasmic translational termination
AMES_RS10025	COG1695	Transcriptional regulator
AMES_RS10030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMES_RS10040	COG1120	ATPase activity
AMES_RS10045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AMES_RS10050	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AMES_RS10060	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AMES_RS10110	COG0402	S-adenosylhomocysteine deaminase activity
AMES_RS10125	COG0402	S-adenosylhomocysteine deaminase activity
AMES_RS10165	COG0789	Transcriptional regulator
AMES_RS10185	COG3795	YCII-related domain
AMES_RS10190	COG0702	epimerase
AMES_RS10205	COG1476	TRANSCRIPTIONal
AMES_RS10215	COG3795	YCII-related domain
AMES_RS10220	COG4941	Belongs to the sigma-70 factor family
AMES_RS10240	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AMES_RS10250	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS10265	COG0596	Alpha beta hydrolase
AMES_RS10275	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AMES_RS10285	COG2814	Major facilitator Superfamily
AMES_RS10290	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AMES_RS10300	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AMES_RS10305	COG0750	zinc metalloprotease
AMES_RS10310	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AMES_RS10340	COG0454	-acetyltransferase
AMES_RS10340	COG0456	acetyltransferase
AMES_RS10375	COG2186	Transcriptional regulator
AMES_RS10410	COG0513	Belongs to the DEAD box helicase family
AMES_RS10445	COG0583	DNA-binding transcription factor activity
AMES_RS10455	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AMES_RS10460	COG3022	response to hydroperoxide
AMES_RS10495	COG0442	prolyl-tRNA aminoacylation
AMES_RS10510	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AMES_RS10565	COG1017	nitric oxide dioxygenase activity
AMES_RS10565	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AMES_RS10580	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AMES_RS10600	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AMES_RS10630	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AMES_RS10650	COG4152	abc transporter atp-binding protein
AMES_RS10655	COG1668	transmembrane transport
AMES_RS10665	COG3201	nicotinamide mononucleotide transporter
AMES_RS10670	COG1620	l-lactate permease
AMES_RS10680	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS10690	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AMES_RS10815	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AMES_RS10845	COG0477	Major facilitator Superfamily
AMES_RS10865	COG1960	acyl-CoA dehydrogenase activity
AMES_RS10875	COG1104	cysteine desulfurase activity
AMES_RS10885	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AMES_RS10905	COG1113	amino acid transport
AMES_RS10910	COG2186	Transcriptional regulator
AMES_RS10915	COG0587	DNA-directed DNA polymerase activity
AMES_RS10920	COG0477	Major facilitator Superfamily
AMES_RS10945	COG1376	ErfK ybiS ycfS ynhG family protein
AMES_RS10955	COG0586	Pfam SNARE associated Golgi protein
AMES_RS10960	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AMES_RS10975	COG1309	transcriptional regulator
AMES_RS10985	COG0321	lipoyl(octanoyl) transferase activity
AMES_RS10995	COG1090	epimerase
AMES_RS11005	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AMES_RS11055	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AMES_RS11065	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AMES_RS11065	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AMES_RS11080	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AMES_RS11085	COG0667	Aldo Keto reductase
AMES_RS11105	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AMES_RS11115	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AMES_RS11150	COG1845	cytochrome c oxidase, subunit III
AMES_RS11155	COG2010	Cytochrome c
AMES_RS11165	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AMES_RS11200	COG0438	transferase activity, transferring glycosyl groups
AMES_RS11215	COG2124	cytochrome p450
AMES_RS11220	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AMES_RS11225	COG0659	secondary active sulfate transmembrane transporter activity
AMES_RS11230	COG0659	secondary active sulfate transmembrane transporter activity
AMES_RS11235	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AMES_RS11255	COG0501	Belongs to the peptidase M48B family
AMES_RS11260	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AMES_RS11270	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AMES_RS11275	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AMES_RS11280	COG0157	Belongs to the NadC ModD family
AMES_RS11285	COG1404	Belongs to the peptidase S8 family
AMES_RS11325	COG0318	PFAM AMP-dependent synthetase and ligase
AMES_RS11345	COG1674	ftsk spoiiie
AMES_RS11370	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AMES_RS11380	COG5520	Belongs to the glycosyl hydrolase 30 family
AMES_RS11395	COG4566	intracellular signal transduction
AMES_RS11400	COG2197	response regulator
AMES_RS11410	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AMES_RS11420	COG0131	Imidazoleglycerol-phosphate dehydratase
AMES_RS11435	COG2267	carboxylic ester hydrolase activity
AMES_RS11440	COG2409	Drug exporters of the RND superfamily
AMES_RS11445	COG1309	transcriptional regulator
AMES_RS11450	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
AMES_RS11460	COG3959	Transketolase, thiamine diphosphate binding domain
AMES_RS11465	COG3958	Transketolase
AMES_RS11480	COG1960	acyl-CoA dehydrogenase activity
AMES_RS11490	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AMES_RS11495	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AMES_RS11555	COG0107	imidazoleglycerol-phosphate synthase activity
AMES_RS11565	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AMES_RS11600	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AMES_RS11610	COG0134	indole-3-glycerol-phosphate synthase activity
AMES_RS11615	COG0133	tryptophan synthase activity
AMES_RS11620	COG0159	tryptophan synthase activity
AMES_RS11625	COG0789	Transcriptional regulator
AMES_RS11645	COG0174	glutamine synthetase
AMES_RS11660	COG1473	amidohydrolase
AMES_RS11665	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AMES_RS11675	COG0069	glutamate synthase activity
AMES_RS11675	COG0067	glutamate synthase
AMES_RS11675	COG0070	glutamate synthase
AMES_RS11700	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
AMES_RS11725	COG2268	Band 7 protein
AMES_RS11735	COG2815	serine threonine protein kinase
AMES_RS11735	COG0515	serine threonine protein kinase
AMES_RS11765	COG0142	geranyltranstransferase activity
AMES_RS11820	COG0242	peptide deformylase activity
AMES_RS11825	COG1201	RNA secondary structure unwinding
AMES_RS11830	COG1349	DNA-binding transcription factor activity
AMES_RS11840	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AMES_RS11850	COG0443	Heat shock 70 kDa protein
AMES_RS11860	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AMES_RS11865	COG2137	regulation of response to DNA damage stimulus
AMES_RS11885	COG0800	Aldolase
AMES_RS11905	COG1053	succinate dehydrogenase
AMES_RS11935	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS11940	COG0765	amino acid transport
AMES_RS11945	COG0765	amino acid transport
AMES_RS11950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMES_RS11955	COG1126	abc transporter atp-binding protein
AMES_RS11965	COG3850	Histidine kinase
AMES_RS11965	COG0642	Histidine kinase
AMES_RS11975	COG1733	regulation of RNA biosynthetic process
AMES_RS12040	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AMES_RS12055	COG1196	nuclear chromosome segregation
AMES_RS12060	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AMES_RS12070	COG0525	valine-tRNA ligase activity
AMES_RS12085	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AMES_RS12095	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AMES_RS12105	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AMES_RS12110	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AMES_RS12130	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AMES_RS12140	COG1505	serine-type exopeptidase activity
AMES_RS12175	COG2936	dipeptidyl-peptidase activity
AMES_RS12180	COG1434	Gram-negative-bacterium-type cell wall biogenesis
AMES_RS12190	COG2197	response regulator
AMES_RS12195	COG4585	Histidine kinase
AMES_RS12210	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AMES_RS12215	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AMES_RS12230	COG0123	including yeast histone deacetylase and acetoin utilization protein
AMES_RS12245	COG1960	acyl-CoA dehydrogenase activity
AMES_RS12250	COG1960	acyl-CoA dehydrogenase activity
AMES_RS12260	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS12270	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AMES_RS12275	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AMES_RS12325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AMES_RS12340	COG1609	Transcriptional regulator
AMES_RS12355	COG0395	ABC-type sugar transport system, permease component
AMES_RS12360	COG2723	6-phospho-beta-galactosidase activity
AMES_RS12385	COG0003	Pfam Anion-transporting ATPase
AMES_RS12395	COG1940	carbohydrate kinase activity
AMES_RS12410	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AMES_RS12435	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AMES_RS12470	COG0640	Transcriptional regulator
AMES_RS12490	COG1946	Acyl-CoA thioesterase
AMES_RS12510	COG2197	response regulator
AMES_RS12515	COG1012	belongs to the aldehyde dehydrogenase family
AMES_RS12530	COG1960	acyl-CoA dehydrogenase activity
AMES_RS12535	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AMES_RS12560	COG1566	PFAM secretion protein HlyD family protein
AMES_RS12575	COG1309	transcriptional regulator
AMES_RS12580	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AMES_RS12595	COG2018	Roadblock/LC7 domain
AMES_RS12625	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AMES_RS12625	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AMES_RS12625	COG1703	isobutyryl-CoA mutase activity
AMES_RS12635	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMES_RS12640	COG1309	transcriptional regulator
AMES_RS12645	COG1960	acyl-CoA dehydrogenase activity
AMES_RS12650	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AMES_RS12660	COG0657	acetylesterase activity
AMES_RS12665	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AMES_RS12670	COG0748	coenzyme F420 binding
AMES_RS12680	COG1960	acyl-CoA dehydrogenase activity
AMES_RS12685	COG1960	acyl-CoA dehydrogenase activity
AMES_RS12690	COG2030	dehydratase
AMES_RS12710	COG0196	riboflavin kinase activity
AMES_RS12715	COG2030	dehydratase
AMES_RS12735	COG1053	succinate dehydrogenase
AMES_RS12745	COG1960	acyl-CoA dehydrogenase activity
AMES_RS12750	COG2267	carboxylic ester hydrolase activity
AMES_RS12755	COG0346	lactoylglutathione lyase activity
AMES_RS12760	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AMES_RS12785	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AMES_RS12805	COG0583	DNA-binding transcription factor activity
AMES_RS12815	COG0446	pyridine nucleotide-disulphide oxidoreductase
AMES_RS12865	COG1473	amidohydrolase
AMES_RS12875	COG1228	amidohydrolase
AMES_RS12880	COG0596	Alpha beta hydrolase
AMES_RS12885	COG0183	Belongs to the thiolase family
AMES_RS12890	COG2124	cytochrome p450
AMES_RS12905	COG1295	ribonuclease BN
AMES_RS12935	COG2070	2-Nitropropane dioxygenase
AMES_RS12950	COG2188	Transcriptional regulator
AMES_RS12970	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AMES_RS12970	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AMES_RS12980	COG1490	D-aminoacyl-tRNA deacylase activity
AMES_RS12985	COG2890	protein-(glutamine-N5) methyltransferase activity
AMES_RS13005	COG2313	pseudouridylate synthase activity
AMES_RS13030	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AMES_RS13045	COG4213	ABC transporter substrate-binding protein
AMES_RS13055	COG4214	carbohydrate transport
AMES_RS13085	COG0531	amino acid
AMES_RS13115	COG0366	Alpha amylase catalytic
AMES_RS13120	COG0366	Alpha amylase catalytic
AMES_RS13130	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AMES_RS13145	COG1940	carbohydrate kinase activity
AMES_RS13150	COG0483	inositol monophosphate 1-phosphatase activity
AMES_RS13170	COG0756	dUTP diphosphatase activity
AMES_RS13200	COG0569	domain protein
AMES_RS13205	COG0531	amino acid
AMES_RS13210	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AMES_RS13220	COG1012	belongs to the aldehyde dehydrogenase family
AMES_RS13225	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AMES_RS13230	COG1609	Transcriptional regulator
AMES_RS13240	COG1012	belongs to the aldehyde dehydrogenase family
AMES_RS13245	COG0028	Belongs to the TPP enzyme family
AMES_RS13265	COG0745	RESPONSE REGULATOR receiver
AMES_RS13270	COG2205	protein histidine kinase activity
AMES_RS13275	COG0657	acetylesterase activity
AMES_RS13290	COG1250	3-hydroxyacyl-CoA dehydrogenase
AMES_RS13290	COG1024	Enoyl-CoA hydratase
AMES_RS13295	COG0183	Belongs to the thiolase family
AMES_RS13330	COG0531	amino acid
AMES_RS13345	COG2197	response regulator
AMES_RS13355	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AMES_RS13365	COG3253	May function as heme-dependent peroxidase
AMES_RS13370	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AMES_RS13380	COG3220	belongs to the UPF0276 family
AMES_RS13395	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AMES_RS13425	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMES_RS13430	COG0539	negative regulation of cytoplasmic translation
AMES_RS13440	COG2508	Transcriptional regulator
AMES_RS13440	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AMES_RS13445	COG1012	belongs to the aldehyde dehydrogenase family
AMES_RS13450	COG0506	proline dehydrogenase activity
AMES_RS13455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AMES_RS13465	COG3795	YCII-related domain
AMES_RS13475	COG4941	Belongs to the sigma-70 factor family
AMES_RS13485	COG1793	dna ligase
AMES_RS13510	COG1302	Protein conserved in bacteria
AMES_RS13520	COG1595	DNA-templated transcription, initiation
AMES_RS13555	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AMES_RS13560	COG0640	Transcriptional regulator
AMES_RS13570	COG2326	polyphosphate kinase activity
AMES_RS13585	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AMES_RS13590	COG1993	acr, cog1993
AMES_RS13595	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AMES_RS13625	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AMES_RS13625	COG1672	PFAM Archaeal ATPase
AMES_RS13650	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AMES_RS13675	COG2124	cytochrome p450
AMES_RS13695	COG2084	Dehydrogenase
AMES_RS13710	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AMES_RS13720	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AMES_RS13725	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AMES_RS13730	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AMES_RS13735	COG1309	transcriptional regulator
AMES_RS13745	COG1073	alpha beta
AMES_RS13755	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AMES_RS13765	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AMES_RS13770	COG1263	PTS System
AMES_RS13775	COG2188	Transcriptional regulator
AMES_RS13780	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AMES_RS13785	COG1263	PTS System
AMES_RS13785	COG2190	(PTS) system
AMES_RS13785	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AMES_RS13810	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AMES_RS13815	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AMES_RS13820	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AMES_RS13825	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AMES_RS13830	COG0346	lactoylglutathione lyase activity
AMES_RS13845	COG0006	proline dipeptidase activity
AMES_RS13850	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AMES_RS13855	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AMES_RS13875	COG0540	Belongs to the ATCase OTCase family
AMES_RS13890	COG0505	Belongs to the CarA family
AMES_RS13895	COG0419	ATPase involved in DNA repair
AMES_RS13910	COG0284	orotidine-5'-phosphate decarboxylase activity
AMES_RS13920	COG0194	GDP metabolic process
AMES_RS13925	COG1758	RNA polymerase activity
AMES_RS13935	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AMES_RS13960	COG0405	Gamma-glutamyltransferase
AMES_RS13965	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AMES_RS13990	COG2197	response regulator
AMES_RS13995	COG4585	Histidine kinase
AMES_RS14010	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AMES_RS14010	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AMES_RS14015	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AMES_RS14035	COG0322	excinuclease ABC activity
AMES_RS14040	COG1660	Displays ATPase and GTPase activities
AMES_RS14050	COG1481	regulation of sporulation
AMES_RS14055	COG0463	Glycosyl transferase, family 2
AMES_RS14080	COG3250	beta-galactosidase activity
AMES_RS14085	COG0408	coproporphyrinogen oxidase activity
AMES_RS14125	COG1280	lysine exporter protein (LysE YggA)
AMES_RS14135	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AMES_RS14140	COG0126	phosphoglycerate kinase activity
AMES_RS14145	COG0149	triose-phosphate isomerase activity
AMES_RS14165	COG0363	glucosamine-6-phosphate deaminase activity
AMES_RS14180	COG0166	Belongs to the GPI family
AMES_RS14185	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AMES_RS14195	COG0109	protoheme IX farnesyltransferase activity
AMES_RS14300	COG0396	ATPase activity
AMES_RS14315	COG2151	metal-sulfur cluster biosynthetic enzyme
AMES_RS14325	COG1742	UPF0060 membrane protein
AMES_RS14335	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AMES_RS14345	COG4585	Histidine kinase
AMES_RS14355	COG2226	methyltransferase
AMES_RS14390	COG0457	Tetratricopeptide repeat
AMES_RS14450	COG0488	(ABC) transporter
AMES_RS14475	COG1132	(ABC) transporter
AMES_RS14480	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AMES_RS14485	COG4821	SIS domain
AMES_RS14495	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AMES_RS14500	COG1316	TRANSCRIPTIONal
AMES_RS14505	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AMES_RS14515	COG5001	Diguanylate cyclase
AMES_RS14515	COG3300	MHYT domain
AMES_RS14530	COG1051	belongs to the nudix hydrolase family
AMES_RS14540	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AMES_RS14540	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AMES_RS14550	COG1024	Enoyl-CoA hydratase
AMES_RS14575	COG1960	acyl-CoA dehydrogenase activity
AMES_RS14580	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AMES_RS14595	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS14620	COG3469	chitinase activity
AMES_RS14655	COG1309	transcriptional regulator
AMES_RS14660	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AMES_RS14670	COG3693	PFAM glycoside hydrolase, family 10
AMES_RS14700	COG1309	transcriptional regulator
AMES_RS14705	COG0789	Transcriptional regulator
AMES_RS14720	COG2319	Wd-40 repeat
AMES_RS14720	COG4249	Peptidase C14 caspase catalytic subunit p20
AMES_RS14735	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AMES_RS14800	COG2197	response regulator
AMES_RS14865	COG0300	oxidoreductase activity
AMES_RS14875	COG1846	Transcriptional regulator
AMES_RS14890	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AMES_RS14905	COG1595	DNA-templated transcription, initiation
AMES_RS14915	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AMES_RS14925	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AMES_RS14930	COG1799	cell septum assembly
AMES_RS14940	COG3599	regulation of cell shape
AMES_RS14950	COG0640	Transcriptional regulator
AMES_RS14955	COG0477	Major facilitator Superfamily
AMES_RS14960	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AMES_RS14970	COG0640	Transcriptional regulator
AMES_RS14975	COG3263	regulation of cellular component size
AMES_RS14980	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AMES_RS14990	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AMES_RS15015	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMES_RS15025	COG0248	Ppx GppA phosphatase
AMES_RS15070	COG1940	carbohydrate kinase activity
AMES_RS15070	COG1846	Transcriptional regulator
AMES_RS15080	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
AMES_RS15105	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AMES_RS15105	COG2010	Cytochrome c
AMES_RS15130	COG1309	transcriptional regulator
AMES_RS15135	COG4221	oxidoreductase activity
AMES_RS15140	COG0667	Aldo Keto reductase
AMES_RS15145	COG0542	response to heat
AMES_RS15155	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AMES_RS15165	COG0514	ATP-dependent DNA helicase (RecQ)
AMES_RS15175	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS15210	COG2205	protein histidine kinase activity
AMES_RS15215	COG0745	RESPONSE REGULATOR receiver
AMES_RS15225	COG0076	glutamate decarboxylase activity
AMES_RS15280	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AMES_RS15290	COG1131	(ABC) transporter
AMES_RS15310	COG0604	alcohol dehydrogenase
AMES_RS15320	COG2764	glyoxalase bleomycin resistance protein dioxygenase
AMES_RS15340	COG4585	Histidine kinase
AMES_RS15350	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AMES_RS15355	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AMES_RS15360	COG2080	2 iron, 2 sulfur cluster binding
AMES_RS15385	COG2188	Transcriptional regulator
AMES_RS15395	COG1063	alcohol dehydrogenase
AMES_RS15410	COG2172	sigma factor antagonist activity
AMES_RS15415	COG1366	Belongs to the anti-sigma-factor antagonist family
AMES_RS15420	COG1366	Belongs to the anti-sigma-factor antagonist family
AMES_RS15445	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS15450	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AMES_RS15460	COG3546	catalase activity
AMES_RS15470	COG0702	epimerase
AMES_RS15475	COG1733	regulation of RNA biosynthetic process
AMES_RS15500	COG1609	Transcriptional regulator
AMES_RS15510	COG1175	transmembrane transport
AMES_RS15515	COG0395	ABC-type sugar transport system, permease component
AMES_RS15535	COG0667	Aldo Keto reductase
AMES_RS15545	COG0667	Aldo Keto reductase
AMES_RS15555	COG2378	regulation of single-species biofilm formation
AMES_RS15565	COG1691	(AIR) carboxylase
AMES_RS15570	COG3875	lactate racemase activity
AMES_RS15575	COG3618	amidohydrolase
AMES_RS15580	COG0179	Fumarylacetoacetate (FAA) hydrolase
AMES_RS15585	COG4948	Mandelate Racemase Muconate Lactonizing
AMES_RS15600	COG1129	ABC transporter
AMES_RS15640	COG1609	Transcriptional regulator
AMES_RS15645	COG0318	PFAM AMP-dependent synthetase and ligase
AMES_RS15665	COG3251	PFAM MbtH domain protein
AMES_RS15685	COG2124	cytochrome p450
AMES_RS15710	COG0604	alcohol dehydrogenase
AMES_RS15725	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AMES_RS15780	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS15800	COG3250	beta-galactosidase activity
AMES_RS15820	COG1309	transcriptional regulator
AMES_RS15825	COG0596	Alpha beta hydrolase
AMES_RS15835	COG1960	acyl-CoA dehydrogenase activity
AMES_RS15840	COG1960	acyl-CoA dehydrogenase activity
AMES_RS15865	COG4948	Mandelate Racemase Muconate Lactonizing
AMES_RS15880	COG0395	ABC-type sugar transport system, permease component
AMES_RS15885	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AMES_RS15890	COG0515	serine threonine protein kinase
AMES_RS15925	COG2814	Major facilitator Superfamily
AMES_RS15935	COG2205	protein histidine kinase activity
AMES_RS15940	COG0745	RESPONSE REGULATOR receiver
AMES_RS15955	COG1131	(ABC) transporter
AMES_RS15975	COG1309	transcriptional regulator
AMES_RS15985	COG1136	(ABC) transporter
AMES_RS16000	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AMES_RS16005	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMES_RS16015	COG1595	DNA-templated transcription, initiation
AMES_RS16035	COG0596	Alpha beta hydrolase
AMES_RS16045	COG0477	Major facilitator Superfamily
AMES_RS16090	COG0366	Alpha amylase catalytic
AMES_RS16105	COG0395	ABC-type sugar transport system, permease component
AMES_RS16110	COG1175	transmembrane transport
AMES_RS16125	COG1349	DNA-binding transcription factor activity
AMES_RS16135	COG1609	Transcriptional regulator
AMES_RS16140	COG2815	serine threonine protein kinase
AMES_RS16140	COG0515	serine threonine protein kinase
AMES_RS16145	COG2815	serine threonine protein kinase
AMES_RS16145	COG0515	serine threonine protein kinase
AMES_RS16160	COG0437	4 iron, 4 sulfur cluster binding
AMES_RS16165	COG3383	formate dehydrogenase (NAD+) activity
AMES_RS16165	COG0243	molybdopterin cofactor binding
AMES_RS16170	COG0243	molybdopterin cofactor binding
AMES_RS16175	COG2271	Major facilitator Superfamily
AMES_RS16190	COG2318	DinB family
AMES_RS16220	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AMES_RS16230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMES_RS16235	COG0583	DNA-binding transcription factor activity
AMES_RS16245	COG1053	succinate dehydrogenase
AMES_RS16250	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AMES_RS16285	COG3511	phospholipase C
AMES_RS16320	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AMES_RS16325	COG3938	Belongs to the proline racemase family
AMES_RS16335	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AMES_RS16335	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AMES_RS16340	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AMES_RS16350	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AMES_RS16355	COG0395	ABC-type sugar transport system, permease component
AMES_RS16360	COG1175	transmembrane transport
AMES_RS16410	COG0628	permease
AMES_RS16415	COG3507	Belongs to the glycosyl hydrolase 43 family
AMES_RS16420	COG3285	dna ligase
AMES_RS16420	COG1793	dna ligase
AMES_RS16435	COG2226	methyltransferase
AMES_RS16475	COG1250	3-hydroxyacyl-CoA dehydrogenase
AMES_RS16480	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AMES_RS16485	COG1024	Enoyl-CoA hydratase
AMES_RS16500	COG1012	belongs to the aldehyde dehydrogenase family
AMES_RS16570	COG3507	Belongs to the glycosyl hydrolase 43 family
AMES_RS16640	COG1309	transcriptional regulator
AMES_RS16645	COG1595	DNA-templated transcription, initiation
AMES_RS16660	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS16665	COG0028	Belongs to the TPP enzyme family
AMES_RS16685	COG2018	Roadblock/LC7 domain
AMES_RS16705	COG2188	Transcriptional regulator
AMES_RS16710	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AMES_RS16715	COG0395	ABC-type sugar transport system, permease component
AMES_RS16720	COG1175	transmembrane transport
AMES_RS16725	COG2182	Extracellular solute-binding protein
AMES_RS16735	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AMES_RS16780	COG1609	Transcriptional regulator
AMES_RS16810	COG3591	Belongs to the peptidase S1B family
AMES_RS16835	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AMES_RS16865	COG2267	carboxylic ester hydrolase activity
AMES_RS16895	COG2357	RelA SpoT domain protein
AMES_RS16920	COG1280	lysine exporter protein (LysE YggA)
AMES_RS16925	COG0484	heat shock protein binding
AMES_RS16930	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AMES_RS16955	COG2409	Drug exporters of the RND superfamily
AMES_RS16965	COG0318	PFAM AMP-dependent synthetase and ligase
AMES_RS16975	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AMES_RS17015	COG1024	Enoyl-CoA hydratase
AMES_RS17035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMES_RS17040	COG0183	Belongs to the thiolase family
AMES_RS17050	COG1960	acyl-CoA dehydrogenase activity
AMES_RS17055	COG0318	PFAM AMP-dependent synthetase and ligase
AMES_RS17060	COG1024	Enoyl-CoA hydratase
AMES_RS17065	COG1960	acyl-CoA dehydrogenase activity
AMES_RS17070	COG1960	acyl-CoA dehydrogenase activity
AMES_RS17075	COG1960	acyl-CoA dehydrogenase activity
AMES_RS17090	COG1802	Transcriptional regulator
AMES_RS17095	COG3591	Belongs to the peptidase S1B family
AMES_RS17095	COG1864	DNA RNA non-specific endonuclease
AMES_RS17110	COG1063	alcohol dehydrogenase
AMES_RS17115	COG2267	carboxylic ester hydrolase activity
AMES_RS17135	COG1309	transcriptional regulator
AMES_RS17140	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AMES_RS17155	COG3345	alpha-galactosidase
AMES_RS17170	COG1175	transmembrane transport
AMES_RS17175	COG0395	ABC-type sugar transport system, permease component
AMES_RS17200	COG5640	endopeptidase activity
AMES_RS17210	COG0477	Major facilitator Superfamily
AMES_RS17220	COG1940	carbohydrate kinase activity
AMES_RS17225	COG0531	amino acid
AMES_RS17230	COG3250	beta-galactosidase activity
AMES_RS17235	COG1940	carbohydrate kinase activity
AMES_RS17245	COG1609	Transcriptional regulator
AMES_RS17260	COG2124	cytochrome p450
AMES_RS17300	COG1846	Transcriptional regulator
AMES_RS17305	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMES_RS17355	COG0318	PFAM AMP-dependent synthetase and ligase
AMES_RS17385	COG0702	epimerase
AMES_RS17410	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AMES_RS17425	COG4948	Mandelate Racemase Muconate Lactonizing
AMES_RS17445	COG0601	transmembrane transport
AMES_RS17450	COG0444	Belongs to the ABC transporter superfamily
AMES_RS17455	COG4608	Belongs to the ABC transporter superfamily
AMES_RS17465	COG0477	Major facilitator Superfamily
AMES_RS17500	COG0477	Major facilitator Superfamily
AMES_RS17510	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AMES_RS17525	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AMES_RS17525	COG4221	oxidoreductase activity
AMES_RS17525	COG0604	alcohol dehydrogenase
AMES_RS17525	COG3321	synthase
AMES_RS17530	COG3507	Belongs to the glycosyl hydrolase 43 family
AMES_RS17545	COG1231	oxidoreductase activity
AMES_RS17555	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AMES_RS17555	COG0235	Class ii aldolase
AMES_RS17570	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS17575	COG0701	Predicted permease
AMES_RS17600	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS17610	COG0318	PFAM AMP-dependent synthetase and ligase
AMES_RS17620	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS17630	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AMES_RS17665	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AMES_RS17695	COG0501	Belongs to the peptidase M48B family
AMES_RS17730	COG0475	glutathione-regulated potassium exporter activity
AMES_RS17730	COG0569	domain protein
AMES_RS17765	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AMES_RS17770	COG4279	zinc finger
AMES_RS17805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AMES_RS17835	COG0069	glutamate synthase activity
AMES_RS17840	COG0745	RESPONSE REGULATOR receiver
AMES_RS17845	COG5002	protein histidine kinase activity
AMES_RS17860	COG1136	(ABC) transporter
AMES_RS17860	COG0577	efflux transmembrane transporter activity
AMES_RS17865	COG1136	(ABC) transporter
AMES_RS17865	COG0577	efflux transmembrane transporter activity
AMES_RS17880	COG2814	Major facilitator Superfamily
AMES_RS17885	COG0596	Alpha beta hydrolase
AMES_RS17895	COG4585	Histidine kinase
AMES_RS17925	COG4585	Histidine kinase
AMES_RS17970	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
AMES_RS18015	COG0702	epimerase
AMES_RS18040	COG0745	RESPONSE REGULATOR receiver
AMES_RS18045	COG2205	protein histidine kinase activity
AMES_RS18065	COG0726	polysaccharide deacetylase
AMES_RS18115	COG0604	alcohol dehydrogenase
AMES_RS18180	COG4221	oxidoreductase activity
AMES_RS18185	COG4249	Peptidase C14 caspase catalytic subunit p20
AMES_RS18185	COG2319	Wd-40 repeat
AMES_RS18255	COG2197	response regulator
AMES_RS18260	COG0736	holo-[acyl-carrier-protein] synthase activity
AMES_RS18335	COG1834	amidinotransferase
AMES_RS18345	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AMES_RS18350	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AMES_RS18355	COG2080	2 iron, 2 sulfur cluster binding
AMES_RS18365	COG3345	alpha-galactosidase
AMES_RS18405	COG1309	transcriptional regulator
AMES_RS18435	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS18440	COG0583	DNA-binding transcription factor activity
AMES_RS18465	COG3250	beta-galactosidase activity
AMES_RS18510	COG0596	Alpha beta hydrolase
AMES_RS18515	COG0583	DNA-binding transcription factor activity
AMES_RS18605	COG2205	protein histidine kinase activity
AMES_RS18670	COG1522	sequence-specific DNA binding
AMES_RS18680	COG3321	synthase
AMES_RS18680	COG4221	oxidoreductase activity
AMES_RS18680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AMES_RS18680	COG0604	alcohol dehydrogenase
AMES_RS18735	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AMES_RS18745	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AMES_RS18750	COG2080	2 iron, 2 sulfur cluster binding
AMES_RS18785	COG0631	protein serine/threonine phosphatase activity
AMES_RS18825	COG3509	depolymerase
AMES_RS18845	COG0601	transmembrane transport
AMES_RS18855	COG4608	Belongs to the ABC transporter superfamily
AMES_RS18865	COG1609	Transcriptional regulator
AMES_RS18870	COG4124	Belongs to the glycosyl hydrolase 26 family
AMES_RS18880	COG1846	Transcriptional regulator
AMES_RS18880	COG1940	carbohydrate kinase activity
AMES_RS18890	COG1960	acyl-CoA dehydrogenase activity
AMES_RS18895	COG2207	Transcriptional regulator
AMES_RS18965	COG0745	RESPONSE REGULATOR receiver
AMES_RS18970	COG2205	protein histidine kinase activity
AMES_RS18980	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AMES_RS18980	COG2755	lipolytic protein G-D-S-L family
AMES_RS18995	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AMES_RS18995	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AMES_RS19005	COG2267	carboxylic ester hydrolase activity
AMES_RS19010	COG2226	methyltransferase
AMES_RS19020	COG0640	Transcriptional regulator
AMES_RS19055	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AMES_RS19065	COG0375	protein maturation
AMES_RS19075	COG0409	Hydrogenase expression formation protein
AMES_RS19120	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AMES_RS19130	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AMES_RS19165	COG3903	Transcriptional regulator
AMES_RS19165	COG3629	intracellular signal transduction
AMES_RS19170	COG0596	Alpha beta hydrolase
AMES_RS19175	COG1024	Enoyl-CoA hydratase
AMES_RS19175	COG1250	3-hydroxyacyl-CoA dehydrogenase
AMES_RS19180	COG1733	regulation of RNA biosynthetic process
AMES_RS19205	COG0604	alcohol dehydrogenase
AMES_RS19205	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS19205	COG3321	synthase
AMES_RS19210	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS19215	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMES_RS19225	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS19255	COG0411	ABC transporter
AMES_RS19265	COG1024	Enoyl-CoA hydratase
AMES_RS19270	COG1960	acyl-CoA dehydrogenase activity
AMES_RS19275	COG0318	PFAM AMP-dependent synthetase and ligase
AMES_RS19280	COG1946	Acyl-CoA thioesterase
AMES_RS19290	COG1024	Enoyl-CoA hydratase
AMES_RS19295	COG1960	acyl-CoA dehydrogenase activity
AMES_RS19300	COG1012	belongs to the aldehyde dehydrogenase family
AMES_RS19310	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AMES_RS19315	COG0183	Belongs to the thiolase family
AMES_RS19355	COG1946	Acyl-CoA thioesterase
AMES_RS19375	COG1960	acyl-CoA dehydrogenase activity
AMES_RS19395	COG0183	Belongs to the thiolase family
AMES_RS19410	COG0183	Belongs to the thiolase family
AMES_RS19415	COG1024	Enoyl-CoA hydratase
AMES_RS19430	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS19445	COG1024	Enoyl-CoA hydratase
AMES_RS19455	COG1960	acyl-CoA dehydrogenase activity
AMES_RS19460	COG1960	acyl-CoA dehydrogenase activity
AMES_RS19490	COG1960	acyl-CoA dehydrogenase activity
AMES_RS19505	COG1012	belongs to the aldehyde dehydrogenase family
AMES_RS19510	COG1960	acyl-CoA dehydrogenase activity
AMES_RS19515	COG1960	acyl-CoA dehydrogenase activity
AMES_RS19520	COG1024	Enoyl-CoA hydratase
AMES_RS19525	COG2188	Transcriptional regulator
AMES_RS19530	COG0300	oxidoreductase activity
AMES_RS19535	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AMES_RS19565	COG1309	transcriptional regulator
AMES_RS19575	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AMES_RS19580	COG3629	intracellular signal transduction
AMES_RS19580	COG3903	Transcriptional regulator
AMES_RS19600	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AMES_RS19600	COG1017	nitric oxide dioxygenase activity
AMES_RS19605	COG1846	Transcriptional regulator
AMES_RS19605	COG1940	carbohydrate kinase activity
AMES_RS19625	COG0531	amino acid
AMES_RS19630	COG3387	PFAM Glycoside hydrolase 15-related
AMES_RS19635	COG2814	Major facilitator Superfamily
AMES_RS19650	COG2197	response regulator
AMES_RS19685	COG0628	permease
AMES_RS19700	COG1486	melibiose metabolic process
AMES_RS19705	COG0395	ABC-type sugar transport system, permease component
AMES_RS19725	COG1349	DNA-binding transcription factor activity
AMES_RS19730	COG2222	sugar isomerase
AMES_RS19745	COG1105	Belongs to the carbohydrate kinase PfkB family
AMES_RS19820	COG0596	Alpha beta hydrolase
AMES_RS19830	COG1024	Enoyl-CoA hydratase
AMES_RS19830	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AMES_RS19835	COG3629	intracellular signal transduction
AMES_RS19835	COG3903	Transcriptional regulator
AMES_RS19845	COG1132	(ABC) transporter
AMES_RS19870	COG0318	PFAM AMP-dependent synthetase and ligase
AMES_RS19890	COG4221	oxidoreductase activity
AMES_RS19895	COG4948	Mandelate Racemase Muconate Lactonizing
AMES_RS19900	COG0395	ABC-type sugar transport system, permease component
AMES_RS19905	COG3833	ABC-type maltose transport systems, permease component
AMES_RS19940	COG2124	cytochrome p450
AMES_RS19945	COG2175	clavaminate synthase activity
AMES_RS19950	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS19950	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AMES_RS19950	COG4221	oxidoreductase activity
AMES_RS19950	COG3321	synthase
AMES_RS19955	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AMES_RS19960	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS20005	COG1940	carbohydrate kinase activity
AMES_RS20010	COG1846	Transcriptional regulator
AMES_RS20010	COG1940	carbohydrate kinase activity
AMES_RS20020	COG1172	Belongs to the binding-protein-dependent transport system permease family
AMES_RS20030	COG0673	inositol 2-dehydrogenase activity
AMES_RS20040	COG0604	alcohol dehydrogenase
AMES_RS20115	COG1064	alcohol dehydrogenase
AMES_RS20120	COG1309	transcriptional regulator
AMES_RS20125	COG0318	PFAM AMP-dependent synthetase and ligase
AMES_RS20140	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AMES_RS20145	COG1472	Belongs to the glycosyl hydrolase 3 family
AMES_RS20165	COG2508	Transcriptional regulator
AMES_RS20170	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AMES_RS20180	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AMES_RS20185	COG0463	Glycosyl transferase, family 2
AMES_RS20195	COG0318	PFAM AMP-dependent synthetase and ligase
AMES_RS20205	COG3629	intracellular signal transduction
AMES_RS20210	COG0583	DNA-binding transcription factor activity
AMES_RS20220	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS20230	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS20235	COG1846	Transcriptional regulator
AMES_RS20240	COG3629	intracellular signal transduction
AMES_RS20240	COG3903	Transcriptional regulator
AMES_RS20245	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AMES_RS20260	COG2197	response regulator
AMES_RS20270	COG0577	efflux transmembrane transporter activity
AMES_RS20270	COG1136	(ABC) transporter
AMES_RS20300	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AMES_RS20330	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AMES_RS20345	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS20355	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AMES_RS20360	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AMES_RS20365	COG3629	intracellular signal transduction
AMES_RS20365	COG3903	Transcriptional regulator
AMES_RS20370	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AMES_RS20390	COG3509	depolymerase
AMES_RS20395	COG2205	protein histidine kinase activity
AMES_RS20400	COG0745	RESPONSE REGULATOR receiver
AMES_RS20405	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AMES_RS20415	COG0583	DNA-binding transcription factor activity
AMES_RS20440	COG1250	3-hydroxyacyl-CoA dehydrogenase
AMES_RS20470	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AMES_RS20515	COG0142	geranyltranstransferase activity
AMES_RS20535	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AMES_RS20560	COG0395	ABC-type sugar transport system, permease component
AMES_RS20580	COG1609	Transcriptional regulator
AMES_RS20610	COG0653	protein targeting
AMES_RS20635	COG1366	Belongs to the anti-sigma-factor antagonist family
AMES_RS20635	COG2172	sigma factor antagonist activity
AMES_RS20635	COG2208	phosphoserine phosphatase activity
AMES_RS20655	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMES_RS20665	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AMES_RS20685	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AMES_RS20690	COG1012	belongs to the aldehyde dehydrogenase family
AMES_RS20695	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AMES_RS20730	COG3661	Belongs to the glycosyl hydrolase 67 family
AMES_RS20745	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS20790	COG2201	protein-glutamate methylesterase activity
AMES_RS20795	COG2201	protein-glutamate methylesterase activity
AMES_RS20815	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AMES_RS20860	COG0477	Major facilitator Superfamily
AMES_RS20875	COG2318	DinB family
AMES_RS20880	COG1793	dna ligase
AMES_RS20910	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
AMES_RS20920	COG2814	Major facilitator Superfamily
AMES_RS20930	COG2855	membrane
AMES_RS20940	COG0583	DNA-binding transcription factor activity
AMES_RS20970	COG0439	Biotin carboxylase
AMES_RS21010	COG0477	Major facilitator Superfamily
AMES_RS21035	COG0318	PFAM AMP-dependent synthetase and ligase
AMES_RS21060	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AMES_RS21080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AMES_RS21115	COG3285	dna ligase
AMES_RS21115	COG1793	dna ligase
AMES_RS21130	COG0657	acetylesterase activity
AMES_RS21145	COG2267	carboxylic ester hydrolase activity
AMES_RS21180	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AMES_RS21195	COG3634	alkyl hydroperoxide reductase activity
AMES_RS21215	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AMES_RS21275	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AMES_RS21290	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AMES_RS21300	COG2890	protein-(glutamine-N5) methyltransferase activity
AMES_RS21320	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AMES_RS21325	COG2124	cytochrome p450
AMES_RS21335	COG2201	protein-glutamate methylesterase activity
AMES_RS21350	COG2815	serine threonine protein kinase
AMES_RS21350	COG0515	serine threonine protein kinase
AMES_RS21360	COG0326	Molecular chaperone. Has ATPase activity
AMES_RS21370	COG3794	PFAM blue (type 1) copper domain protein
AMES_RS21435	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS21450	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AMES_RS21475	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AMES_RS21485	COG0300	oxidoreductase activity
AMES_RS21490	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AMES_RS21490	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AMES_RS21495	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AMES_RS21500	COG2192	nodulation
AMES_RS21505	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AMES_RS21520	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AMES_RS21520	COG0463	Glycosyl transferase, family 2
AMES_RS21525	COG0297	glycogen (starch) synthase activity
AMES_RS21570	COG1959	2 iron, 2 sulfur cluster binding
AMES_RS21570	COG1295	ribonuclease BN
AMES_RS21595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AMES_RS21595	COG0723	plastoquinol--plastocyanin reductase activity
AMES_RS21600	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AMES_RS21605	COG2890	protein-(glutamine-N5) methyltransferase activity
AMES_RS21620	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AMES_RS21630	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AMES_RS21640	COG1982	Orn Lys Arg decarboxylase major
AMES_RS21660	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AMES_RS21685	COG0596	Alpha beta hydrolase
AMES_RS21710	COG3835	regulator
AMES_RS21735	COG3284	Transcriptional regulator
AMES_RS21780	COG0459	protein refolding
AMES_RS21810	COG0596	Alpha beta hydrolase
AMES_RS21815	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS21820	COG0435	Glutathione S-transferase
AMES_RS21830	COG2353	YceI-like domain
AMES_RS21835	COG1309	transcriptional regulator
AMES_RS21850	COG0395	ABC-type sugar transport system, permease component
AMES_RS21855	COG1175	transmembrane transport
AMES_RS21865	COG1609	Transcriptional regulator
AMES_RS21870	COG1472	Belongs to the glycosyl hydrolase 3 family
AMES_RS21880	COG2124	cytochrome p450
AMES_RS21890	COG1716	ATPase activity
AMES_RS21890	COG5001	Diguanylate cyclase
AMES_RS21905	COG0247	lactate metabolic process
AMES_RS21905	COG2181	nitrate reductase activity
AMES_RS21910	COG1716	ATPase activity
AMES_RS21920	COG0477	Major facilitator Superfamily
AMES_RS21930	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AMES_RS21935	COG3185	4-Hydroxyphenylpyruvate dioxygenase
AMES_RS21935	COG1082	Xylose isomerase domain protein TIM barrel
AMES_RS21940	COG2182	Extracellular solute-binding protein
AMES_RS21945	COG1175	transmembrane transport
AMES_RS21950	COG0395	ABC-type sugar transport system, permease component
AMES_RS21955	COG1472	Belongs to the glycosyl hydrolase 3 family
AMES_RS21965	COG4991	sh3 domain protein
AMES_RS22040	COG0302	gtp cyclohydrolase
AMES_RS22055	COG1609	Transcriptional regulator
AMES_RS22075	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS22090	COG1686	Belongs to the peptidase S11 family
AMES_RS22100	COG1609	Transcriptional regulator
AMES_RS22105	COG1879	ABC-type sugar transport system periplasmic component
AMES_RS22115	COG1172	Belongs to the binding-protein-dependent transport system permease family
AMES_RS22120	COG1172	Belongs to the binding-protein-dependent transport system permease family
AMES_RS22140	COG2160	L-arabinose isomerase activity
AMES_RS22150	COG1129	ABC transporter
AMES_RS22155	COG4214	carbohydrate transport
AMES_RS22165	COG1609	Transcriptional regulator
AMES_RS22175	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AMES_RS22180	COG1414	Transcriptional regulator
AMES_RS22190	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AMES_RS22195	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AMES_RS22205	COG0137	argininosuccinate synthase activity
AMES_RS22250	COG0277	FAD linked oxidase domain protein
AMES_RS22255	COG1609	Transcriptional regulator
AMES_RS22265	COG1653	transport
AMES_RS22270	COG1175	transmembrane transport
AMES_RS22275	COG0395	ABC-type sugar transport system, permease component
AMES_RS22285	COG0673	inositol 2-dehydrogenase activity
AMES_RS22290	COG0673	inositol 2-dehydrogenase activity
AMES_RS22300	COG3866	Pectate lyase
AMES_RS22330	COG3629	intracellular signal transduction
AMES_RS22330	COG3903	Transcriptional regulator
AMES_RS22345	COG0589	response to stress
AMES_RS22350	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AMES_RS22410	COG1090	epimerase
AMES_RS22435	COG0297	glycogen (starch) synthase activity
AMES_RS22460	COG3250	beta-galactosidase activity
AMES_RS22475	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AMES_RS22520	COG0477	Major facilitator Superfamily
AMES_RS22525	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AMES_RS22525	COG3321	synthase
AMES_RS22525	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AMES_RS22530	COG0318	PFAM AMP-dependent synthetase and ligase
AMES_RS22545	COG0300	oxidoreductase activity
AMES_RS22550	COG1819	glycosyl
AMES_RS22560	COG1793	dna ligase
AMES_RS22560	COG3285	dna ligase
AMES_RS22570	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AMES_RS22585	COG2267	carboxylic ester hydrolase activity
AMES_RS22600	COG3903	Transcriptional regulator
AMES_RS22600	COG3629	intracellular signal transduction
AMES_RS22605	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AMES_RS22615	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AMES_RS22615	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AMES_RS22615	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AMES_RS22630	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AMES_RS22650	COG1472	Belongs to the glycosyl hydrolase 3 family
AMES_RS22655	COG1609	Transcriptional regulator
AMES_RS22670	COG0395	ABC-type sugar transport system, permease component
AMES_RS22680	COG1609	Transcriptional regulator
AMES_RS22700	COG1278	Cold shock
AMES_RS22705	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AMES_RS22755	COG0387	Pfam Sodium calcium exchanger
AMES_RS22760	COG0583	DNA-binding transcription factor activity
AMES_RS22765	COG0028	Belongs to the TPP enzyme family
AMES_RS22810	COG1609	Transcriptional regulator
AMES_RS22815	COG1129	ABC transporter
AMES_RS22820	COG1172	Belongs to the binding-protein-dependent transport system permease family
AMES_RS22825	COG1172	Belongs to the binding-protein-dependent transport system permease family
AMES_RS22835	COG3254	rhamnose metabolic process
AMES_RS22845	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS22845	COG3347	Dehydrogenase
AMES_RS22855	COG1070	Carbohydrate kinase
AMES_RS22860	COG2197	response regulator
AMES_RS22865	COG4585	Histidine kinase
AMES_RS22880	COG3250	beta-galactosidase activity
AMES_RS22935	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AMES_RS22940	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AMES_RS22955	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AMES_RS22970	COG0045	succinate-CoA ligase (ADP-forming) activity
AMES_RS22980	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AMES_RS22990	COG2223	nitrite transmembrane transporter activity
AMES_RS22995	COG1802	Transcriptional regulator
AMES_RS23000	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AMES_RS23005	COG3383	formate dehydrogenase (NAD+) activity
AMES_RS23010	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AMES_RS23015	COG1034	ATP synthesis coupled electron transport
AMES_RS23020	COG3622	Belongs to the hyi family
AMES_RS23025	COG2084	Dehydrogenase
AMES_RS23030	COG3960	tartronate-semialdehyde synthase activity
AMES_RS23045	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AMES_RS23050	COG0590	tRNA wobble adenosine to inosine editing
AMES_RS23055	COG2252	PERMEase
AMES_RS23065	COG1929	Belongs to the glycerate kinase type-1 family
AMES_RS23120	COG2066	Belongs to the glutaminase family
AMES_RS23135	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AMES_RS23150	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AMES_RS23155	COG0596	Alpha beta hydrolase
AMES_RS23165	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS23180	COG3285	dna ligase
AMES_RS23180	COG1793	dna ligase
AMES_RS23185	COG0183	Belongs to the thiolase family
AMES_RS23230	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AMES_RS23235	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AMES_RS23240	COG1609	Transcriptional regulator
AMES_RS23250	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AMES_RS23255	COG2267	carboxylic ester hydrolase activity
AMES_RS23290	COG0667	Aldo Keto reductase
AMES_RS23295	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMES_RS23300	COG1968	undecaprenyl-diphosphatase activity
AMES_RS23310	COG0339	signal peptide processing
AMES_RS23315	COG0740	serine-type endopeptidase activity
AMES_RS23320	COG0039	L-malate dehydrogenase activity
AMES_RS23355	COG3537	Alpha-1,2-mannosidase
AMES_RS23395	COG0747	negative chemotaxis
AMES_RS23400	COG0601	transmembrane transport
AMES_RS23405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AMES_RS23410	COG4172	Belongs to the ABC transporter superfamily
AMES_RS23430	COG1619	proteins homologs of microcin C7 resistance protein MccF
AMES_RS23435	COG0823	Involved in the tonB-independent uptake of proteins
AMES_RS23435	COG1506	peptidase
AMES_RS23435	COG4946	Tricorn protease homolog
AMES_RS23495	COG0477	Major facilitator Superfamily
AMES_RS23515	COG0640	Transcriptional regulator
AMES_RS23560	COG4941	Belongs to the sigma-70 factor family
AMES_RS23625	COG4941	Belongs to the sigma-70 factor family
AMES_RS23635	COG2124	cytochrome p450
AMES_RS23655	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AMES_RS23670	COG1309	transcriptional regulator
AMES_RS23680	COG1960	acyl-CoA dehydrogenase activity
AMES_RS23685	COG1309	transcriptional regulator
AMES_RS23700	COG1396	sequence-specific DNA binding
AMES_RS23715	COG0640	Transcriptional regulator
AMES_RS23725	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AMES_RS23750	COG1435	thymidine kinase activity
AMES_RS23760	COG0494	nUDIX hydrolase
AMES_RS23770	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AMES_RS23775	COG0463	Glycosyl transferase, family 2
AMES_RS23785	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AMES_RS23805	COG4977	sequence-specific DNA binding
AMES_RS23810	COG1733	regulation of RNA biosynthetic process
AMES_RS23830	COG3629	intracellular signal transduction
AMES_RS23830	COG3903	Transcriptional regulator
AMES_RS23865	COG4865	methylaspartate mutase activity
AMES_RS23870	COG0017	Asparaginyl-tRNA synthetase
AMES_RS23875	COG0069	glutamate synthase activity
AMES_RS23890	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AMES_RS23940	COG1250	3-hydroxyacyl-CoA dehydrogenase
AMES_RS23965	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AMES_RS23990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AMES_RS24050	COG4948	Mandelate Racemase Muconate Lactonizing
AMES_RS24055	COG2186	Transcriptional regulator
AMES_RS24060	COG0395	ABC-type sugar transport system, permease component
AMES_RS24065	COG1175	transmembrane transport
AMES_RS24070	COG3293	Transposase
AMES_RS24090	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AMES_RS24100	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AMES_RS24105	COG4865	methylaspartate mutase activity
AMES_RS24115	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AMES_RS24160	COG0789	Transcriptional regulator
AMES_RS24210	COG2124	cytochrome p450
AMES_RS24245	COG2197	response regulator
AMES_RS24250	COG2197	response regulator
AMES_RS24260	COG0823	Involved in the tonB-independent uptake of proteins
AMES_RS24365	COG0402	S-adenosylhomocysteine deaminase activity
AMES_RS24370	COG1414	Transcriptional regulator
AMES_RS24375	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AMES_RS24385	COG3485	protocatechuate 3,4-dioxygenase
AMES_RS24405	COG3979	chitinase
AMES_RS24415	COG1136	(ABC) transporter
AMES_RS24420	COG1136	(ABC) transporter
AMES_RS24435	COG4221	oxidoreductase activity
AMES_RS24440	COG0583	DNA-binding transcription factor activity
AMES_RS24450	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AMES_RS24490	COG4552	Acetyltransferase involved in intracellular survival and related
AMES_RS24495	COG4552	Acetyltransferase involved in intracellular survival and related
AMES_RS24515	COG1597	lipid kinase activity
AMES_RS24525	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AMES_RS24535	COG2378	regulation of single-species biofilm formation
AMES_RS24545	COG1733	regulation of RNA biosynthetic process
AMES_RS24555	COG4221	oxidoreductase activity
AMES_RS24565	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
AMES_RS24580	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
AMES_RS24585	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
AMES_RS24620	COG0640	Transcriptional regulator
AMES_RS24635	COG0697	spore germination
AMES_RS24640	COG1222	aaa ATPase
AMES_RS24665	COG1994	Peptidase M50
AMES_RS24665	COG0517	IMP dehydrogenase activity
AMES_RS24680	COG1192	Involved in chromosome partitioning
AMES_RS24685	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AMES_RS24690	COG0140	phosphoribosyl-ATP diphosphatase activity
AMES_RS24705	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AMES_RS24710	COG1410	methionine synthase
AMES_RS24710	COG0646	methionine synthase
AMES_RS24730	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AMES_RS24745	COG2814	Major facilitator Superfamily
AMES_RS24760	COG0488	(ABC) transporter
AMES_RS24765	COG0215	cysteine-tRNA ligase activity
AMES_RS24775	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AMES_RS24785	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
AMES_RS24800	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AMES_RS24815	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AMES_RS24825	COG0477	Major facilitator Superfamily
AMES_RS24830	COG0745	RESPONSE REGULATOR receiver
AMES_RS24835	COG2205	protein histidine kinase activity
AMES_RS24850	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AMES_RS24860	COG2304	oxidoreductase activity
AMES_RS24870	COG0714	Associated with various cellular activities
AMES_RS24875	COG0746	molybdenum cofactor guanylyltransferase activity
AMES_RS24880	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AMES_RS24885	COG0791	NLP P60 protein
AMES_RS24885	COG3883	PFAM NLP P60 protein
AMES_RS24890	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AMES_RS24895	COG1285	pathogenesis
AMES_RS24905	COG1309	transcriptional regulator
AMES_RS24920	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
AMES_RS24930	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AMES_RS24935	COG3572	ergothioneine biosynthetic process
AMES_RS24945	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AMES_RS24950	COG2267	carboxylic ester hydrolase activity
AMES_RS24975	COG1309	transcriptional regulator
AMES_RS25015	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AMES_RS25035	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AMES_RS25035	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AMES_RS25055	COG0789	Transcriptional regulator
AMES_RS25070	COG1716	ATPase activity
AMES_RS25100	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AMES_RS25105	COG1024	Enoyl-CoA hydratase
AMES_RS25115	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AMES_RS25115	COG1648	precorrin-2 dehydrogenase activity
AMES_RS25130	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AMES_RS25135	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AMES_RS25140	COG0254	rRNA binding
AMES_RS25160	COG2814	Major facilitator Superfamily
AMES_RS25180	COG2211	Major facilitator Superfamily
AMES_RS25185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMES_RS25220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMES_RS25230	COG1116	anion transmembrane transporter activity
AMES_RS25235	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AMES_RS25240	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AMES_RS25245	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AMES_RS25270	COG1132	(ABC) transporter
AMES_RS25285	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AMES_RS25295	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMES_RS25300	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMES_RS25305	COG1120	ATPase activity
AMES_RS25315	COG3486	L-lysine 6-monooxygenase (NADPH) activity
AMES_RS25345	COG0395	ABC-type sugar transport system, permease component
AMES_RS25350	COG0488	(ABC) transporter
AMES_RS25395	COG3293	Transposase
AMES_RS25465	COG3250	beta-galactosidase activity
AMES_RS25485	COG4948	Mandelate Racemase Muconate Lactonizing
AMES_RS25495	COG4948	Mandelate Racemase Muconate Lactonizing
AMES_RS25500	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AMES_RS25510	COG1116	anion transmembrane transporter activity
AMES_RS25515	COG2205	protein histidine kinase activity
AMES_RS25520	COG0745	RESPONSE REGULATOR receiver
AMES_RS25550	COG1846	Transcriptional regulator
AMES_RS25565	COG0028	Belongs to the TPP enzyme family
AMES_RS25570	COG1073	alpha beta
AMES_RS25575	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS25580	COG0179	Fumarylacetoacetate (FAA) hydrolase
AMES_RS25590	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AMES_RS25610	COG1129	ABC transporter
AMES_RS25615	COG1172	Belongs to the binding-protein-dependent transport system permease family
AMES_RS25635	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AMES_RS25660	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AMES_RS25665	COG0463	Glycosyl transferase, family 2
AMES_RS25675	COG3250	beta-galactosidase activity
AMES_RS25700	COG4221	oxidoreductase activity
AMES_RS25725	COG0709	Synthesizes selenophosphate from selenide and ATP
AMES_RS25755	COG2367	Beta-lactamase
AMES_RS25760	COG2249	NAD(P)H dehydrogenase (quinone) activity
AMES_RS25775	COG2267	carboxylic ester hydrolase activity
AMES_RS25810	COG0596	Alpha beta hydrolase
AMES_RS25815	COG1309	transcriptional regulator
AMES_RS25870	COG2409	Drug exporters of the RND superfamily
AMES_RS25890	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AMES_RS25895	COG0019	diaminopimelate decarboxylase activity
AMES_RS25945	COG2201	protein-glutamate methylesterase activity
AMES_RS25950	COG4585	Histidine kinase
AMES_RS25960	COG2197	response regulator
AMES_RS25975	COG1324	tolerance protein
AMES_RS26030	COG2814	Major facilitator Superfamily
AMES_RS26065	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AMES_RS26070	COG0667	Aldo Keto reductase
AMES_RS26095	COG5297	Belongs to the glycosyl hydrolase family 6
AMES_RS26100	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
AMES_RS26105	COG5297	Belongs to the glycosyl hydrolase family 6
AMES_RS26105	COG4733	cellulase activity
AMES_RS26125	COG0395	ABC-type sugar transport system, permease component
AMES_RS26135	COG0129	dihydroxy-acid dehydratase activity
AMES_RS26150	COG1573	uracil-dna glycosylase
AMES_RS26155	COG1793	dna ligase
AMES_RS26155	COG3285	dna ligase
AMES_RS26165	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
AMES_RS26265	COG0583	DNA-binding transcription factor activity
AMES_RS26270	COG0019	diaminopimelate decarboxylase activity
AMES_RS26295	COG0477	Major facilitator Superfamily
AMES_RS26300	COG0456	acetyltransferase
AMES_RS26310	COG3209	COG3209 Rhs family protein
AMES_RS26310	COG4104	PAAR repeat-containing protein
AMES_RS26390	COG1472	Belongs to the glycosyl hydrolase 3 family
AMES_RS26420	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AMES_RS26450	COG0456	acetyltransferase
AMES_RS26455	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AMES_RS26470	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
AMES_RS26490	COG2018	Roadblock/LC7 domain
AMES_RS26495	COG2205	protein histidine kinase activity
AMES_RS26530	COG3903	Transcriptional regulator
AMES_RS26530	COG3629	intracellular signal transduction
AMES_RS26555	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AMES_RS26575	COG1250	3-hydroxyacyl-CoA dehydrogenase
AMES_RS26575	COG1024	Enoyl-CoA hydratase
AMES_RS26605	COG0402	S-adenosylhomocysteine deaminase activity
AMES_RS26610	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AMES_RS26615	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AMES_RS26620	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AMES_RS26625	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AMES_RS26630	COG1862	Preprotein translocase
AMES_RS26635	COG2255	four-way junction helicase activity
AMES_RS26640	COG0632	four-way junction helicase activity
AMES_RS26645	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AMES_RS26660	COG0217	transcriptional regulatory protein
AMES_RS26665	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
AMES_RS26680	COG1396	sequence-specific DNA binding
AMES_RS26685	COG0644	oxidoreductase
AMES_RS26690	COG1960	acyl-CoA dehydrogenase activity
AMES_RS26710	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
AMES_RS26720	COG0277	FAD linked oxidase domain protein
AMES_RS26730	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AMES_RS26730	COG3608	succinylglutamate desuccinylase aspartoacylase
AMES_RS26750	COG0438	transferase activity, transferring glycosyl groups
AMES_RS26775	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AMES_RS26780	COG0778	Nitroreductase
AMES_RS26820	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AMES_RS26825	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AMES_RS26830	COG0701	Predicted permease
AMES_RS26850	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS26860	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AMES_RS26875	COG1473	amidohydrolase
AMES_RS26890	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AMES_RS26905	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AMES_RS26915	COG0318	PFAM AMP-dependent synthetase and ligase
AMES_RS26955	COG1597	lipid kinase activity
AMES_RS26990	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AMES_RS26995	COG0395	ABC-type sugar transport system, permease component
AMES_RS27000	COG1175	transmembrane transport
AMES_RS27015	COG2072	flavoprotein involved in K transport
AMES_RS27030	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS27085	COG2211	Major facilitator Superfamily
AMES_RS27090	COG1802	Transcriptional regulator
AMES_RS27130	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AMES_RS27170	COG3483	tryptophan 2,3-dioxygenase activity
AMES_RS27185	COG2197	response regulator
AMES_RS27190	COG4585	Histidine kinase
AMES_RS27200	COG1131	(ABC) transporter
AMES_RS27210	COG3510	cephalosporin hydroxylase
AMES_RS27215	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AMES_RS27225	COG1819	glycosyl
AMES_RS27235	COG1819	glycosyl
AMES_RS27275	COG3629	intracellular signal transduction
AMES_RS27280	COG1819	glycosyl
AMES_RS27285	COG3848	Pyruvate phosphate dikinase
AMES_RS27285	COG0574	Belongs to the PEP-utilizing enzyme family
AMES_RS27300	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS27320	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS27330	COG2867	negative regulation of translational initiation
AMES_RS27335	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AMES_RS27340	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AMES_RS27345	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AMES_RS27350	COG0662	Cupin 2, conserved barrel domain protein
AMES_RS27365	COG3104	oligopeptide transport
AMES_RS27370	COG2345	Transcriptional regulator
AMES_RS27375	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AMES_RS27395	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS27470	COG0659	secondary active sulfate transmembrane transporter activity
AMES_RS27480	COG0589	response to stress
AMES_RS27500	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AMES_RS27515	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AMES_RS27540	COG1271	oxidase subunit
AMES_RS27545	COG1294	oxidase, subunit
AMES_RS27550	COG4988	ABC transporter
AMES_RS27555	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
AMES_RS27565	COG0517	IMP dehydrogenase activity
AMES_RS27565	COG0617	tRNA 3'-terminal CCA addition
AMES_RS27565	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AMES_RS27600	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AMES_RS27620	COG4585	Histidine kinase
AMES_RS27625	COG2197	response regulator
AMES_RS27645	COG4585	Histidine kinase
AMES_RS27650	COG2197	response regulator
AMES_RS27705	COG2197	response regulator
AMES_RS27745	COG0681	Belongs to the peptidase S26 family
AMES_RS27750	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS27810	COG0405	Gamma-glutamyltransferase
AMES_RS27815	COG3706	GGDEF domain
AMES_RS27860	COG1216	Glycosyl transferase, family 2
AMES_RS27865	COG1215	transferase activity, transferring glycosyl groups
AMES_RS27875	COG1132	(ABC) transporter
AMES_RS27890	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AMES_RS27895	COG0596	Alpha beta hydrolase
AMES_RS27950	COG2814	Major facilitator Superfamily
AMES_RS27965	COG3903	Transcriptional regulator
AMES_RS27965	COG3629	intracellular signal transduction
AMES_RS28040	COG0330	HflC and HflK could
AMES_RS28115	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AMES_RS28175	COG0297	glycogen (starch) synthase activity
AMES_RS28180	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AMES_RS28210	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS28215	COG1309	transcriptional regulator
AMES_RS28220	COG4941	Belongs to the sigma-70 factor family
AMES_RS28225	COG4941	Belongs to the sigma-70 factor family
AMES_RS28250	COG0583	DNA-binding transcription factor activity
AMES_RS28290	COG0515	serine threonine protein kinase
AMES_RS28295	COG1595	DNA-templated transcription, initiation
AMES_RS28300	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AMES_RS28355	COG0596	Alpha beta hydrolase
AMES_RS28360	COG0596	Alpha beta hydrolase
AMES_RS28370	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AMES_RS28385	COG1672	PFAM Archaeal ATPase
AMES_RS28385	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
AMES_RS28390	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS28415	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS28445	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AMES_RS28505	COG2205	protein histidine kinase activity
AMES_RS28510	COG0745	RESPONSE REGULATOR receiver
AMES_RS28515	COG1216	Glycosyl transferase, family 2
AMES_RS28520	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AMES_RS28545	COG1609	Transcriptional regulator
AMES_RS28555	COG1309	transcriptional regulator
AMES_RS28610	COG4941	Belongs to the sigma-70 factor family
AMES_RS28630	COG1335	isochorismatase
AMES_RS28660	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AMES_RS28665	COG1309	transcriptional regulator
AMES_RS28680	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
AMES_RS28685	COG1414	Transcriptional regulator
AMES_RS28690	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS28710	COG1278	Cold shock
AMES_RS28730	COG0300	oxidoreductase activity
AMES_RS28740	COG3795	YCII-related domain
AMES_RS28755	COG3263	regulation of cellular component size
AMES_RS28765	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AMES_RS28775	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AMES_RS28815	COG0745	RESPONSE REGULATOR receiver
AMES_RS28820	COG5002	protein histidine kinase activity
AMES_RS28820	COG5000	phosphorelay sensor kinase activity
AMES_RS28845	COG1846	Transcriptional regulator
AMES_RS28850	COG0038	chloride channel
AMES_RS28880	COG0243	molybdopterin cofactor binding
AMES_RS28880	COG3383	formate dehydrogenase (NAD+) activity
AMES_RS28885	COG3383	formate dehydrogenase (NAD+) activity
AMES_RS28885	COG0243	molybdopterin cofactor binding
AMES_RS28890	COG0437	4 iron, 4 sulfur cluster binding
AMES_RS28925	COG2116	formate transmembrane transporter activity
AMES_RS28950	COG0531	amino acid
AMES_RS28955	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AMES_RS28975	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
AMES_RS28980	COG2080	2 iron, 2 sulfur cluster binding
AMES_RS28990	COG0667	Aldo Keto reductase
AMES_RS29035	COG3250	beta-galactosidase activity
AMES_RS29040	COG0395	ABC-type sugar transport system, permease component
AMES_RS29045	COG1175	transmembrane transport
AMES_RS29050	COG1609	Transcriptional regulator
AMES_RS29055	COG1609	Transcriptional regulator
AMES_RS29075	COG1609	Transcriptional regulator
AMES_RS29095	COG2207	Transcriptional regulator
AMES_RS29095	COG1917	Cupin 2, conserved barrel domain protein
AMES_RS29100	COG3250	beta-galactosidase activity
AMES_RS29230	COG3293	Transposase
AMES_RS29255	COG1857	crispr-associated protein
AMES_RS29365	COG4733	cellulase activity
AMES_RS29365	COG5297	Belongs to the glycosyl hydrolase family 6
AMES_RS29390	COG0154	amidase activity
AMES_RS29395	COG0789	Transcriptional regulator
AMES_RS29400	COG0640	Transcriptional regulator
AMES_RS29430	COG0673	inositol 2-dehydrogenase activity
AMES_RS29455	COG1653	transport
AMES_RS29485	COG3842	ATPase activity
AMES_RS29495	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AMES_RS29500	COG0028	Belongs to the TPP enzyme family
AMES_RS29520	COG2197	response regulator
AMES_RS29530	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AMES_RS29540	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AMES_RS29550	COG0702	epimerase
AMES_RS29560	COG0583	DNA-binding transcription factor activity
AMES_RS29570	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AMES_RS29630	COG0300	oxidoreductase activity
AMES_RS29635	COG4221	oxidoreductase activity
AMES_RS29640	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AMES_RS29700	COG2318	DinB family
AMES_RS29705	COG0667	Aldo Keto reductase
AMES_RS29720	COG2267	carboxylic ester hydrolase activity
AMES_RS29730	COG3629	intracellular signal transduction
AMES_RS29730	COG3903	Transcriptional regulator
AMES_RS29790	COG4974	Belongs to the 'phage' integrase family
AMES_RS29795	COG1012	belongs to the aldehyde dehydrogenase family
AMES_RS29845	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AMES_RS29885	COG2815	serine threonine protein kinase
AMES_RS29885	COG0515	serine threonine protein kinase
AMES_RS29900	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AMES_RS29930	COG3511	phospholipase C
AMES_RS29980	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS30030	COG0714	Associated with various cellular activities
AMES_RS30040	COG3552	Protein containing von Willebrand factor type A (VWA) domain
AMES_RS30045	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AMES_RS30055	COG1733	regulation of RNA biosynthetic process
AMES_RS30065	COG5492	domain, Protein
AMES_RS30080	COG4948	Mandelate Racemase Muconate Lactonizing
AMES_RS30085	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AMES_RS30095	COG1414	Transcriptional regulator
AMES_RS30100	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AMES_RS30200	COG1160	GTP binding
AMES_RS30230	COG0475	glutathione-regulated potassium exporter activity
AMES_RS30235	COG2936	dipeptidyl-peptidase activity
AMES_RS30240	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AMES_RS30250	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AMES_RS30280	COG0494	nUDIX hydrolase
AMES_RS30285	COG0504	CTP synthase activity
AMES_RS30295	COG1802	Transcriptional regulator
AMES_RS30300	COG1953	Uracil, thiamine, allantoin
AMES_RS30335	COG1063	alcohol dehydrogenase
AMES_RS30350	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AMES_RS30365	COG0647	UMP catabolic process
AMES_RS30390	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AMES_RS30395	COG2094	Belongs to the DNA glycosylase MPG family
AMES_RS30415	COG0165	Argininosuccinate lyase
AMES_RS30420	COG0137	argininosuccinate synthase activity
AMES_RS30425	COG1438	arginine binding
AMES_RS30430	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AMES_RS30435	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AMES_RS30440	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AMES_RS30445	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AMES_RS30450	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AMES_RS30465	COG0596	Alpha beta hydrolase
AMES_RS30475	COG0072	phenylalanine-tRNA ligase activity
AMES_RS30475	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AMES_RS30480	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AMES_RS30490	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AMES_RS30495	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AMES_RS30500	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AMES_RS30545	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
AMES_RS30550	COG2610	gluconate transmembrane transporter activity
AMES_RS30555	COG2706	6-phosphogluconolactonase activity
AMES_RS30565	COG1175	transmembrane transport
AMES_RS30570	COG0395	ABC-type sugar transport system, permease component
AMES_RS30585	COG4565	transcriptional regulatory protein
AMES_RS30590	COG3290	protein histidine kinase activity
AMES_RS30595	COG1301	dicarboxylic acid transport
AMES_RS30645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AMES_RS30670	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AMES_RS30675	COG0328	RNA-DNA hybrid ribonuclease activity
AMES_RS30680	COG3012	SEC-C Motif Domain Protein
AMES_RS30690	COG3250	beta-galactosidase activity
AMES_RS30695	COG2272	Belongs to the type-B carboxylesterase lipase family
AMES_RS30710	COG0406	alpha-ribazole phosphatase activity
AMES_RS30730	COG1609	Transcriptional regulator
AMES_RS30750	COG1506	peptidase
AMES_RS30750	COG4946	Tricorn protease homolog
AMES_RS30750	COG0823	Involved in the tonB-independent uptake of proteins
AMES_RS30760	COG1131	(ABC) transporter
AMES_RS30780	COG1024	Enoyl-CoA hydratase
AMES_RS30820	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AMES_RS30820	COG0237	dephospho-CoA kinase activity
AMES_RS30845	COG0539	negative regulation of cytoplasmic translation
AMES_RS30850	COG2226	methyltransferase
AMES_RS30870	COG1511	domain protein
AMES_RS30875	COG1309	transcriptional regulator
AMES_RS30880	COG2207	Transcriptional regulator
AMES_RS30885	COG0604	alcohol dehydrogenase
AMES_RS30910	COG0583	DNA-binding transcription factor activity
AMES_RS31180	COG4585	Histidine kinase
AMES_RS31185	COG2197	response regulator
AMES_RS31205	COG2197	response regulator
AMES_RS31210	COG4585	Histidine kinase
AMES_RS31230	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AMES_RS31235	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AMES_RS31255	COG1454	alcohol dehydrogenase
AMES_RS31265	COG1012	belongs to the aldehyde dehydrogenase family
AMES_RS31285	COG0596	Alpha beta hydrolase
AMES_RS31305	COG4977	sequence-specific DNA binding
AMES_RS31310	COG0596	Alpha beta hydrolase
AMES_RS31320	COG0300	oxidoreductase activity
AMES_RS31360	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AMES_RS31405	COG3251	PFAM MbtH domain protein
AMES_RS31460	COG2814	Major facilitator Superfamily
AMES_RS31465	COG0702	epimerase
AMES_RS31475	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AMES_RS31480	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AMES_RS31490	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AMES_RS31495	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AMES_RS31510	COG0768	penicillin binding
AMES_RS31520	COG0275	rRNA processing
AMES_RS31525	COG2001	Belongs to the MraZ family
AMES_RS31555	COG0714	Associated with various cellular activities
AMES_RS31565	COG1305	Transglutaminase-like
AMES_RS31575	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AMES_RS31585	COG1192	Involved in chromosome partitioning
AMES_RS31590	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AMES_RS31595	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AMES_RS31605	COG0167	dihydroorotate dehydrogenase activity
AMES_RS31620	COG1842	Phage shock protein A
AMES_RS31625	COG1396	sequence-specific DNA binding
AMES_RS31630	COG1546	Belongs to the CinA family
AMES_RS31630	COG1058	Belongs to the CinA family
AMES_RS31640	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AMES_RS31645	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AMES_RS31675	COG1674	ftsk spoiiie
AMES_RS31685	COG0655	NAD(P)H dehydrogenase (quinone) activity
AMES_RS31705	COG1113	amino acid transport
AMES_RS31715	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AMES_RS31720	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AMES_RS31725	COG0515	serine threonine protein kinase
AMES_RS31760	COG3214	Protein conserved in bacteria
AMES_RS31800	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AMES_RS31810	COG1185	polyribonucleotide nucleotidyltransferase activity
AMES_RS31815	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AMES_RS31835	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AMES_RS31860	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AMES_RS31870	COG2268	Band 7 protein
AMES_RS31885	COG2226	methyltransferase
AMES_RS31920	COG0195	Participates in both transcription termination and antitermination
AMES_RS31925	COG0779	Required for maturation of 30S ribosomal subunits
AMES_RS31955	COG3226	Transcriptional regulator
AMES_RS31965	COG4585	Histidine kinase
AMES_RS31970	COG2197	response regulator
AMES_RS31980	COG1733	regulation of RNA biosynthetic process
AMES_RS31990	COG1309	transcriptional regulator
AMES_RS31995	COG2936	dipeptidyl-peptidase activity
AMES_RS32010	COG0745	RESPONSE REGULATOR receiver
AMES_RS32015	COG5002	protein histidine kinase activity
AMES_RS32025	COG3903	Transcriptional regulator
AMES_RS32025	COG3629	intracellular signal transduction
AMES_RS32045	COG0583	DNA-binding transcription factor activity
AMES_RS32055	COG1024	Enoyl-CoA hydratase
AMES_RS32065	COG1250	3-hydroxyacyl-CoA dehydrogenase
AMES_RS32070	COG1960	acyl-CoA dehydrogenase activity
AMES_RS32075	COG1316	TRANSCRIPTIONal
AMES_RS32105	COG0583	DNA-binding transcription factor activity
AMES_RS32130	COG2124	cytochrome p450
AMES_RS32145	COG0702	epimerase
AMES_RS32170	COG3903	Transcriptional regulator
AMES_RS32170	COG3629	intracellular signal transduction
AMES_RS32220	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AMES_RS32260	COG1595	DNA-templated transcription, initiation
AMES_RS32285	COG3507	Belongs to the glycosyl hydrolase 43 family
AMES_RS32300	COG4941	Belongs to the sigma-70 factor family
AMES_RS32305	COG3795	YCII-related domain
AMES_RS32310	COG0596	Alpha beta hydrolase
AMES_RS32315	COG1309	transcriptional regulator
AMES_RS32320	COG0604	alcohol dehydrogenase
AMES_RS32345	COG0443	Heat shock 70 kDa protein
AMES_RS32360	COG1228	amidohydrolase
AMES_RS32400	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AMES_RS32430	COG2197	response regulator
AMES_RS32460	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AMES_RS32460	COG2755	lipolytic protein G-D-S-L family
AMES_RS32510	COG3903	Transcriptional regulator
AMES_RS32510	COG3629	intracellular signal transduction
AMES_RS32535	COG0667	Aldo Keto reductase
AMES_RS32565	COG1960	acyl-CoA dehydrogenase activity
AMES_RS32580	COG0318	PFAM AMP-dependent synthetase and ligase
AMES_RS32595	COG0596	Alpha beta hydrolase
AMES_RS32600	COG2197	response regulator
AMES_RS32625	COG0477	Major facilitator Superfamily
AMES_RS32675	COG4585	Histidine kinase
AMES_RS32680	COG2197	response regulator
AMES_RS32695	COG0586	Pfam SNARE associated Golgi protein
AMES_RS32705	COG1968	undecaprenyl-diphosphatase activity
AMES_RS32745	COG4585	Histidine kinase
AMES_RS32750	COG2197	response regulator
AMES_RS32760	COG2201	protein-glutamate methylesterase activity
AMES_RS32775	COG1309	transcriptional regulator
AMES_RS32780	COG0702	epimerase
AMES_RS32785	COG0702	epimerase
AMES_RS32800	COG0657	acetylesterase activity
AMES_RS32810	COG2814	Major facilitator Superfamily
AMES_RS32835	COG4977	sequence-specific DNA binding
AMES_RS32890	COG1120	ATPase activity
AMES_RS32895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMES_RS33010	COG0243	molybdopterin cofactor binding
AMES_RS33060	COG0028	Belongs to the TPP enzyme family
AMES_RS33065	COG4948	Mandelate Racemase Muconate Lactonizing
AMES_RS33070	COG0277	FAD linked oxidase domain protein
AMES_RS33070	COG0247	lactate metabolic process
AMES_RS33095	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AMES_RS33100	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
AMES_RS33110	COG1659	Linocin_M18 bacteriocin protein
AMES_RS33130	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AMES_RS33150	COG4106	trans-aconitate 2-methyltransferase activity
AMES_RS33165	COG1595	DNA-templated transcription, initiation
AMES_RS33180	COG0477	Major facilitator Superfamily
AMES_RS33200	COG2318	DinB family
AMES_RS33215	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AMES_RS33225	COG2197	response regulator
AMES_RS33230	COG4585	Histidine kinase
AMES_RS33240	COG1131	(ABC) transporter
AMES_RS33245	COG0423	glycine-tRNA ligase activity
AMES_RS33285	COG0701	Predicted permease
AMES_RS33295	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AMES_RS33300	COG1381	Involved in DNA repair and RecF pathway recombination
AMES_RS33330	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AMES_RS33345	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AMES_RS33355	COG0537	adenosine 5'-monophosphoramidase activity
AMES_RS33365	COG0484	heat shock protein binding
AMES_RS33395	COG0667	Aldo Keto reductase
AMES_RS33430	COG2205	protein histidine kinase activity
AMES_RS33435	COG0745	RESPONSE REGULATOR receiver
AMES_RS33440	COG1953	Uracil, thiamine, allantoin
AMES_RS33450	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AMES_RS33540	COG0326	Molecular chaperone. Has ATPase activity
AMES_RS33555	COG1024	Enoyl-CoA hydratase
AMES_RS33560	COG2732	(Barnase) inhibitor
AMES_RS33565	COG4290	ribonuclease
AMES_RS33575	COG0604	alcohol dehydrogenase
AMES_RS33585	COG0531	amino acid
AMES_RS33590	COG2070	2-Nitropropane dioxygenase
AMES_RS33650	COG0268	Binds directly to 16S ribosomal RNA
AMES_RS33660	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AMES_RS33670	COG0658	competence protein
AMES_RS33670	COG2333	competence protein COMEC
AMES_RS33680	COG1307	EDD domain protein, DegV family
AMES_RS33690	COG0406	alpha-ribazole phosphatase activity
AMES_RS33695	COG0799	negative regulation of ribosome biogenesis
AMES_RS33700	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AMES_RS33715	COG0018	arginyl-trna synthetase
AMES_RS33735	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS33745	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AMES_RS33750	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AMES_RS33755	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AMES_RS33760	COG1530	ribonuclease E activity
AMES_RS33760	COG1530	ribonuclease E activity
AMES_RS33780	COG1131	(ABC) transporter
AMES_RS33795	COG0105	UTP biosynthetic process
AMES_RS33805	COG2366	antibiotic biosynthetic process
AMES_RS33815	COG0285	dihydrofolate synthase activity
AMES_RS33840	COG0583	DNA-binding transcription factor activity
AMES_RS33845	COG0525	valine-tRNA ligase activity
AMES_RS33855	COG1846	Transcriptional regulator
AMES_RS33860	COG0477	Major facilitator Superfamily
AMES_RS33875	COG1316	TRANSCRIPTIONal
AMES_RS33885	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AMES_RS33915	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AMES_RS33920	COG0740	serine-type endopeptidase activity
AMES_RS33925	COG0740	serine-type endopeptidase activity
AMES_RS33930	COG0544	peptidyl-prolyl cis-trans isomerase activity
AMES_RS33940	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AMES_RS33950	COG2205	protein histidine kinase activity
AMES_RS33955	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AMES_RS34010	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AMES_RS34055	COG3629	intracellular signal transduction
AMES_RS34055	COG3903	Transcriptional regulator
AMES_RS34065	COG3537	Alpha-1,2-mannosidase
AMES_RS34070	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AMES_RS34075	COG3559	Exporter of polyketide antibiotics
AMES_RS34080	COG1131	(ABC) transporter
AMES_RS34085	COG1309	transcriptional regulator
AMES_RS34095	COG1940	carbohydrate kinase activity
AMES_RS34115	COG2814	Major facilitator Superfamily
AMES_RS34150	COG0693	protein deglycase activity
AMES_RS34155	COG2208	phosphoserine phosphatase activity
AMES_RS34160	COG0784	Response regulator, receiver
AMES_RS34160	COG5002	protein histidine kinase activity
AMES_RS34180	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AMES_RS34195	COG1396	sequence-specific DNA binding
AMES_RS34215	COG0583	DNA-binding transcription factor activity
AMES_RS34225	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS34235	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMES_RS34250	COG1733	regulation of RNA biosynthetic process
AMES_RS34255	COG3345	alpha-galactosidase
AMES_RS34280	COG0459	protein refolding
AMES_RS34290	COG0698	ribose 5-phosphate isomerase
AMES_RS34305	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AMES_RS34320	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AMES_RS34340	COG0668	transmembrane transport
AMES_RS34350	COG0366	Alpha amylase catalytic
AMES_RS34370	COG2902	Dehydrogenase
AMES_RS34385	COG3336	cytochrome c oxidase
AMES_RS34400	COG0738	Major facilitator superfamily
AMES_RS34420	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AMES_RS34425	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AMES_RS34445	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
AMES_RS34485	COG0477	Major facilitator Superfamily
AMES_RS34490	COG0596	Alpha beta hydrolase
AMES_RS34510	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AMES_RS34530	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AMES_RS34575	COG2124	cytochrome p450
AMES_RS34610	COG1733	regulation of RNA biosynthetic process
AMES_RS34615	COG4941	Belongs to the sigma-70 factor family
AMES_RS34620	COG3795	YCII-related domain
AMES_RS34630	COG0009	L-threonylcarbamoyladenylate synthase
AMES_RS34645	COG2197	response regulator
AMES_RS34650	COG1917	Cupin 2, conserved barrel domain protein
AMES_RS34650	COG4977	sequence-specific DNA binding
AMES_RS34655	COG2197	response regulator
AMES_RS34660	COG4585	Histidine kinase
AMES_RS34705	COG1937	Protein conserved in bacteria
AMES_RS34745	COG4221	oxidoreductase activity
AMES_RS34760	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AMES_RS34785	COG0657	acetylesterase activity
AMES_RS34805	COG0745	RESPONSE REGULATOR receiver
AMES_RS34810	COG2205	protein histidine kinase activity
AMES_RS34820	COG1609	Transcriptional regulator
AMES_RS34840	COG0366	Alpha amylase catalytic
AMES_RS34855	COG0367	asparagine synthase
AMES_RS34860	COG1940	carbohydrate kinase activity
AMES_RS34880	COG0583	DNA-binding transcription factor activity
AMES_RS34920	COG1609	Transcriptional regulator
AMES_RS34955	COG0531	amino acid
AMES_RS34960	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AMES_RS34990	COG3835	regulator
AMES_RS35015	COG1021	2,3-dihydroxybenzoate-AMP ligase
AMES_RS35035	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AMES_RS35040	COG0583	DNA-binding transcription factor activity
AMES_RS35085	COG1024	Enoyl-CoA hydratase
AMES_RS35145	COG0318	PFAM AMP-dependent synthetase and ligase
AMES_RS35160	COG1643	Atp-dependent helicase
AMES_RS35175	COG3268	Saccharopine dehydrogenase
AMES_RS35180	COG2072	flavoprotein involved in K transport
AMES_RS35195	COG1796	DNA polymerase
AMES_RS35195	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AMES_RS35205	COG1802	Transcriptional regulator
AMES_RS35230	COG3706	GGDEF domain
AMES_RS35240	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
AMES_RS35260	COG4941	Belongs to the sigma-70 factor family
AMES_RS35280	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AMES_RS35295	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AMES_RS35305	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AMES_RS35310	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AMES_RS35315	COG0235	Class ii aldolase
AMES_RS35315	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AMES_RS35335	COG1695	Transcriptional regulator
AMES_RS35345	COG3959	Transketolase, thiamine diphosphate binding domain
AMES_RS35350	COG1309	transcriptional regulator
AMES_RS35355	COG0277	FAD linked oxidase domain protein
AMES_RS35355	COG0247	lactate metabolic process
AMES_RS35365	COG2197	response regulator
AMES_RS35385	COG0559	Belongs to the binding-protein-dependent transport system permease family
AMES_RS35390	COG0559	Belongs to the binding-protein-dependent transport system permease family
AMES_RS35405	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AMES_RS35410	COG3537	Alpha-1,2-mannosidase
AMES_RS35415	COG1739	Uncharacterized protein family UPF0029
AMES_RS35420	COG0069	glutamate synthase activity
AMES_RS35420	COG0067	glutamate synthase
AMES_RS35420	COG0070	glutamate synthase
AMES_RS35430	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AMES_RS35460	COG1492	cobalamin metabolic process
AMES_RS35465	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AMES_RS35475	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AMES_RS35480	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AMES_RS35485	COG2378	regulation of single-species biofilm formation
AMES_RS35500	COG1797	cobyrinic acid a,c-diamide synthase activity
AMES_RS35535	COG0778	Nitroreductase
AMES_RS35565	COG1131	(ABC) transporter
AMES_RS35575	COG1476	TRANSCRIPTIONal
AMES_RS35590	COG3469	chitinase activity
AMES_RS35610	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AMES_RS35635	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AMES_RS35645	COG0433	COG0433 Predicted ATPase
AMES_RS35650	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AMES_RS35660	COG0477	Major facilitator Superfamily
AMES_RS35665	COG1376	ErfK ybiS ycfS ynhG family protein
AMES_RS35880	COG1960	acyl-CoA dehydrogenase activity
AMES_RS35890	COG0022	dehydrogenase e1 component
AMES_RS35895	COG0318	PFAM AMP-dependent synthetase and ligase
AMES_RS35900	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS35905	COG1024	Enoyl-CoA hydratase
AMES_RS35925	COG0477	Major facilitator Superfamily
AMES_RS35935	COG2301	Belongs to the HpcH HpaI aldolase family
AMES_RS35945	COG2186	Transcriptional regulator
AMES_RS35950	COG1012	belongs to the aldehyde dehydrogenase family
AMES_RS35955	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AMES_RS35970	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS36005	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AMES_RS36015	COG1309	transcriptional regulator
AMES_RS36025	COG0604	alcohol dehydrogenase
AMES_RS36080	COG1960	acyl-CoA dehydrogenase activity
AMES_RS36085	COG1960	acyl-CoA dehydrogenase activity
AMES_RS36095	COG2186	Transcriptional regulator
AMES_RS36110	COG0604	alcohol dehydrogenase
AMES_RS36110	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS36110	COG3321	synthase
AMES_RS36115	COG1960	acyl-CoA dehydrogenase activity
AMES_RS36120	COG1960	acyl-CoA dehydrogenase activity
AMES_RS36160	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AMES_RS36175	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS36205	COG1414	Transcriptional regulator
AMES_RS36215	COG2267	carboxylic ester hydrolase activity
AMES_RS36230	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS36235	COG0259	pyridoxamine-phosphate oxidase activity
AMES_RS36240	COG0183	Belongs to the thiolase family
AMES_RS36245	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AMES_RS36250	COG1024	Enoyl-CoA hydratase
AMES_RS36255	COG1960	acyl-CoA dehydrogenase activity
AMES_RS36270	COG0318	PFAM AMP-dependent synthetase and ligase
AMES_RS36280	COG0318	PFAM AMP-dependent synthetase and ligase
AMES_RS36290	COG1024	Enoyl-CoA hydratase
AMES_RS36300	COG1024	Enoyl-CoA hydratase
AMES_RS36320	COG1024	Enoyl-CoA hydratase
AMES_RS36330	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AMES_RS36340	COG1012	belongs to the aldehyde dehydrogenase family
AMES_RS36360	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AMES_RS36395	COG1335	isochorismatase
AMES_RS36415	COG1309	transcriptional regulator
AMES_RS36425	COG0022	dehydrogenase e1 component
AMES_RS36455	COG1063	alcohol dehydrogenase
AMES_RS36465	COG4585	Histidine kinase
AMES_RS36470	COG2197	response regulator
AMES_RS36490	COG4948	Mandelate Racemase Muconate Lactonizing
AMES_RS36495	COG2271	Major facilitator Superfamily
AMES_RS36525	COG0235	Class ii aldolase
AMES_RS36530	COG0477	Major facilitator Superfamily
AMES_RS36535	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AMES_RS36565	COG0673	inositol 2-dehydrogenase activity
AMES_RS36570	COG2211	Major facilitator Superfamily
AMES_RS36575	COG1609	Transcriptional regulator
AMES_RS36580	COG1653	transport
AMES_RS36590	COG0395	ABC-type sugar transport system, permease component
AMES_RS36600	COG0596	Alpha beta hydrolase
AMES_RS36610	COG0596	Alpha beta hydrolase
AMES_RS36625	COG2084	Dehydrogenase
AMES_RS36635	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AMES_RS36640	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AMES_RS36650	COG0189	ligase activity
AMES_RS36665	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AMES_RS36670	COG0625	glutathione transferase activity
AMES_RS36680	COG2271	Major facilitator Superfamily
AMES_RS36695	COG1250	3-hydroxyacyl-CoA dehydrogenase
AMES_RS36880	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AMES_RS36925	COG2856	Zn peptidase
AMES_RS36960	COG0702	epimerase
AMES_RS36975	COG0702	epimerase
AMES_RS36985	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AMES_RS36990	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AMES_RS36995	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMES_RS37000	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS37005	COG2169	Transcriptional regulator
AMES_RS37005	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AMES_RS37075	COG4733	cellulase activity
AMES_RS37075	COG5297	Belongs to the glycosyl hydrolase family 6
AMES_RS37085	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AMES_RS37105	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AMES_RS37140	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AMES_RS37145	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AMES_RS37165	COG1960	acyl-CoA dehydrogenase activity
AMES_RS37190	COG0154	amidase activity
AMES_RS37205	COG0583	DNA-binding transcription factor activity
AMES_RS37245	COG1131	(ABC) transporter
AMES_RS37255	COG3345	alpha-galactosidase
AMES_RS37300	COG0438	transferase activity, transferring glycosyl groups
AMES_RS37320	COG0297	glycogen (starch) synthase activity
AMES_RS37325	COG0438	transferase activity, transferring glycosyl groups
AMES_RS37340	COG0463	Glycosyl transferase, family 2
AMES_RS37375	COG3250	beta-galactosidase activity
AMES_RS37380	COG3401	FG-GAP repeat protein
AMES_RS37400	COG1609	Transcriptional regulator
AMES_RS37410	COG0395	ABC-type sugar transport system, permease component
AMES_RS37415	COG1175	transmembrane transport
AMES_RS37455	COG0596	Alpha beta hydrolase
AMES_RS37460	COG2208	phosphoserine phosphatase activity
AMES_RS37460	COG2770	Histidine kinase
AMES_RS37470	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AMES_RS37480	COG2226	methyltransferase
AMES_RS37490	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AMES_RS37530	COG0667	Aldo Keto reductase
AMES_RS37535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMES_RS37555	COG0587	DNA-directed DNA polymerase activity
AMES_RS37560	COG4941	Belongs to the sigma-70 factor family
AMES_RS37565	COG3795	YCII-related domain
AMES_RS37575	COG1982	Orn Lys Arg decarboxylase major
AMES_RS37590	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AMES_RS37600	COG1725	Transcriptional regulator
AMES_RS37605	COG1131	(ABC) transporter
AMES_RS37625	COG3509	depolymerase
AMES_RS37640	COG1528	Iron-storage protein
AMES_RS37665	COG2018	Roadblock/LC7 domain
AMES_RS37690	COG1764	response to oxidative stress
AMES_RS37700	COG2267	carboxylic ester hydrolase activity
AMES_RS37715	COG0667	Aldo Keto reductase
AMES_RS37720	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AMES_RS37755	COG0395	ABC-type sugar transport system, permease component
AMES_RS37760	COG1175	transmembrane transport
AMES_RS37765	COG1609	Transcriptional regulator
AMES_RS37790	COG0604	alcohol dehydrogenase
AMES_RS37820	COG1595	DNA-templated transcription, initiation
AMES_RS37830	COG0318	PFAM AMP-dependent synthetase and ligase
AMES_RS37835	COG0129	dihydroxy-acid dehydratase activity
AMES_RS37840	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AMES_RS37900	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
AMES_RS37935	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AMES_RS37945	COG2226	methyltransferase
AMES_RS37950	COG2508	Transcriptional regulator
AMES_RS37960	COG3655	Transcriptional regulator
AMES_RS38005	COG4981	capsule polysaccharide biosynthetic process
AMES_RS38030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AMES_RS38035	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AMES_RS38060	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AMES_RS38095	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AMES_RS38110	COG3226	Transcriptional regulator
AMES_RS38115	COG1012	belongs to the aldehyde dehydrogenase family
AMES_RS38170	COG0508	dehydrogenase complex catalyzes the overall conversion of
AMES_RS38195	COG1472	Belongs to the glycosyl hydrolase 3 family
AMES_RS38210	COG0745	RESPONSE REGULATOR receiver
AMES_RS38215	COG5002	protein histidine kinase activity
AMES_RS38245	COG0515	serine threonine protein kinase
AMES_RS38245	COG2815	serine threonine protein kinase
AMES_RS38265	COG0640	Transcriptional regulator
AMES_RS38275	COG2837	iron assimilation
AMES_RS38280	COG3511	phospholipase C
AMES_RS38295	COG0784	Response regulator, receiver
AMES_RS38300	COG4251	negative regulation of phosphorylation
AMES_RS38305	COG0745	RESPONSE REGULATOR receiver
AMES_RS38385	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AMES_RS38410	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AMES_RS38485	COG1309	transcriptional regulator
AMES_RS38510	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AMES_RS38515	COG1309	transcriptional regulator
AMES_RS38535	COG0318	PFAM AMP-dependent synthetase and ligase
AMES_RS38540	COG3383	formate dehydrogenase (NAD+) activity
AMES_RS38545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMES_RS38590	COG2814	Major facilitator Superfamily
AMES_RS38625	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS38655	COG0706	membrane insertase activity
AMES_RS38665	COG1408	metallophosphoesterase
AMES_RS38675	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AMES_RS38680	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AMES_RS38705	COG2018	Roadblock/LC7 domain
AMES_RS38725	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS38735	COG3706	GGDEF domain
AMES_RS38750	COG1316	TRANSCRIPTIONal
AMES_RS38790	COG4977	sequence-specific DNA binding
AMES_RS38795	COG0667	Aldo Keto reductase
AMES_RS38800	COG2207	Transcriptional regulator
AMES_RS38830	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AMES_RS38835	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AMES_RS38840	COG1234	tRNA 3'-trailer cleavage
AMES_RS38845	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AMES_RS38860	COG1794	racemase activity, acting on amino acids and derivatives
AMES_RS38865	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AMES_RS38890	COG3191	aminopeptidase activity
AMES_RS38905	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AMES_RS38910	COG1335	isochorismatase
AMES_RS38915	COG0800	Aldolase
AMES_RS38925	COG1268	BioY protein
AMES_RS38955	COG3830	Belongs to the UPF0237 family
AMES_RS38955	COG0560	Phosphoserine phosphatase
AMES_RS38960	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AMES_RS38970	COG2267	carboxylic ester hydrolase activity
AMES_RS38990	COG2801	Transposase and inactivated derivatives
AMES_RS39005	COG0626	cystathionine gamma-synthase activity
AMES_RS39010	COG1522	sequence-specific DNA binding
AMES_RS39020	COG1522	sequence-specific DNA binding
AMES_RS39055	COG2376	Dihydroxyacetone kinase
AMES_RS39085	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
AMES_RS39090	COG1051	belongs to the nudix hydrolase family
AMES_RS39105	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AMES_RS39110	COG4977	sequence-specific DNA binding
AMES_RS39115	COG1335	isochorismatase
AMES_RS39120	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AMES_RS39120	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AMES_RS39135	COG1280	lysine exporter protein (LysE YggA)
AMES_RS39140	COG1280	lysine exporter protein (LysE YggA)
AMES_RS39150	COG0702	epimerase
AMES_RS39155	COG3631	Ketosteroid isomerase-related protein
AMES_RS39160	COG1309	transcriptional regulator
AMES_RS39175	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AMES_RS39185	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AMES_RS39190	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AMES_RS39195	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AMES_RS39200	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AMES_RS39205	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AMES_RS39210	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AMES_RS39215	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AMES_RS39220	COG0356	it plays a direct role in the translocation of protons across the membrane
AMES_RS39230	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AMES_RS39245	COG2890	protein-(glutamine-N5) methyltransferase activity
AMES_RS39250	COG0463	Glycosyl transferase, family 2
AMES_RS39270	COG0254	rRNA binding
AMES_RS39280	COG0083	homoserine kinase activity
AMES_RS39285	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AMES_RS39290	COG0460	homoserine dehydrogenase
AMES_RS39295	COG0019	diaminopimelate decarboxylase activity
AMES_RS39300	COG0018	arginyl-trna synthetase
AMES_RS39335	COG0596	Alpha beta hydrolase
AMES_RS39415	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AMES_RS39430	COG3629	intracellular signal transduction
AMES_RS39430	COG3903	Transcriptional regulator
AMES_RS39435	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AMES_RS39435	COG2124	cytochrome p450
AMES_RS39455	COG3345	alpha-galactosidase
AMES_RS39475	COG3250	beta-galactosidase activity
AMES_RS39480	COG3693	PFAM glycoside hydrolase, family 10
AMES_RS39545	COG5433	transposase activity
AMES_RS39595	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AMES_RS39600	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AMES_RS39620	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS39630	COG0145	ligase activity
AMES_RS39655	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
AMES_RS39670	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AMES_RS39685	COG0154	amidase activity
AMES_RS39715	COG0473	3-isopropylmalate dehydrogenase activity
AMES_RS39725	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AMES_RS39735	COG0667	Aldo Keto reductase
AMES_RS39755	COG0028	Belongs to the TPP enzyme family
AMES_RS39780	COG4585	Histidine kinase
AMES_RS39785	COG2197	response regulator
AMES_RS39790	COG2409	Drug exporters of the RND superfamily
AMES_RS39795	COG3537	Alpha-1,2-mannosidase
AMES_RS39800	COG1250	3-hydroxyacyl-CoA dehydrogenase
AMES_RS39800	COG1024	Enoyl-CoA hydratase
AMES_RS39805	COG0183	Belongs to the thiolase family
AMES_RS39810	COG1309	transcriptional regulator
AMES_RS39845	COG1960	acyl-CoA dehydrogenase activity
AMES_RS39850	COG1960	acyl-CoA dehydrogenase activity
AMES_RS39910	COG4221	oxidoreductase activity
AMES_RS39940	COG1960	acyl-CoA dehydrogenase activity
AMES_RS39950	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AMES_RS39980	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AMES_RS39995	COG0346	lactoylglutathione lyase activity
AMES_RS40015	COG2226	methyltransferase
AMES_RS40020	COG2508	Transcriptional regulator
AMES_RS40020	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AMES_RS40035	COG0686	Belongs to the AlaDH PNT family
AMES_RS40045	COG2205	protein histidine kinase activity
AMES_RS40055	COG0745	RESPONSE REGULATOR receiver
AMES_RS40070	COG1132	(ABC) transporter
AMES_RS40085	COG0567	Dehydrogenase, E1 component
AMES_RS40085	COG0508	dehydrogenase complex catalyzes the overall conversion of
AMES_RS40095	COG1216	Glycosyl transferase, family 2
AMES_RS40100	COG2223	nitrite transmembrane transporter activity
AMES_RS40110	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMES_RS40125	COG1174	glycine betaine transport
AMES_RS40130	COG1174	glycine betaine transport
AMES_RS40135	COG1125	glycine betaine transport
AMES_RS40135	COG0517	IMP dehydrogenase activity
AMES_RS40150	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
AMES_RS40160	COG1846	Transcriptional regulator
AMES_RS40175	COG0406	alpha-ribazole phosphatase activity
AMES_RS40190	COG1597	lipid kinase activity
AMES_RS40215	COG1595	DNA-templated transcription, initiation
AMES_RS40220	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AMES_RS40230	COG2135	peptidase activity
AMES_RS40260	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AMES_RS40265	COG1011	Hydrolase
AMES_RS40280	COG0653	protein targeting
AMES_RS40285	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AMES_RS40295	COG5401	PFAM Sporulation and spore germination
AMES_RS40300	COG5000	phosphorelay sensor kinase activity
AMES_RS40300	COG5002	protein histidine kinase activity
AMES_RS40305	COG0745	RESPONSE REGULATOR receiver
AMES_RS40315	COG1414	Transcriptional regulator
AMES_RS40385	COG0531	amino acid
AMES_RS40395	COG3903	Transcriptional regulator
AMES_RS40395	COG3629	intracellular signal transduction
AMES_RS40400	COG1482	cell wall glycoprotein biosynthetic process
AMES_RS40410	COG2835	tetraacyldisaccharide 4'-kinase activity
AMES_RS40415	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AMES_RS40455	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AMES_RS40470	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AMES_RS40475	COG0601	transmembrane transport
AMES_RS40485	COG0747	negative chemotaxis
AMES_RS40490	COG1217	gtp-binding protein TYPA
AMES_RS40500	COG0180	Tryptophanyl-tRNA synthetase
AMES_RS40505	COG0494	nUDIX hydrolase
AMES_RS40505	COG0406	alpha-ribazole phosphatase activity
AMES_RS40515	COG0745	RESPONSE REGULATOR receiver
AMES_RS40525	COG1131	(ABC) transporter
AMES_RS40535	COG3842	ATPase activity
AMES_RS40540	COG4149	molybdate abc transporter
AMES_RS40550	COG2154	pterin-4-alpha-carbinolamine dehydratase
AMES_RS40570	COG0012	GTP binding
AMES_RS40585	COG0419	ATPase involved in DNA repair
AMES_RS40590	COG0420	3'-5' exonuclease activity
AMES_RS40605	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AMES_RS40615	COG1570	exodeoxyribonuclease VII activity
AMES_RS40625	COG1722	exodeoxyribonuclease VII activity
AMES_RS40640	COG0492	ferredoxin-NADP+ reductase activity
AMES_RS40645	COG0114	fumarate hydratase activity
AMES_RS40655	COG1793	dna ligase
AMES_RS40670	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AMES_RS40695	COG1228	amidohydrolase
AMES_RS40700	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AMES_RS40725	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
AMES_RS40755	COG1331	Highly conserved protein containing a thioredoxin domain
AMES_RS40770	COG2890	protein-(glutamine-N5) methyltransferase activity
AMES_RS40775	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AMES_RS40785	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AMES_RS40795	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AMES_RS40800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AMES_RS40810	COG3185	4-Hydroxyphenylpyruvate dioxygenase
AMES_RS40840	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AMES_RS40875	COG0183	Belongs to the thiolase family
AMES_RS40950	COG3903	Transcriptional regulator
AMES_RS40950	COG3629	intracellular signal transduction
AMES_RS40955	COG2723	6-phospho-beta-galactosidase activity
AMES_RS40965	COG1175	transmembrane transport
AMES_RS40980	COG1472	Belongs to the glycosyl hydrolase 3 family
AMES_RS40985	COG0667	Aldo Keto reductase
AMES_RS40995	COG0477	Major facilitator Superfamily
AMES_RS41025	COG2207	Transcriptional regulator
AMES_RS41040	COG5297	Belongs to the glycosyl hydrolase family 6
AMES_RS41055	COG2205	protein histidine kinase activity
AMES_RS41060	COG0148	phosphopyruvate hydratase activity
AMES_RS41070	COG1132	(ABC) transporter
AMES_RS41170	COG0515	serine threonine protein kinase
AMES_RS41170	COG2815	serine threonine protein kinase
AMES_RS41205	COG1191	sigma factor activity
AMES_RS41275	COG1515	deoxyribonuclease V activity
AMES_RS41290	COG4608	Belongs to the ABC transporter superfamily
AMES_RS41295	COG0444	Belongs to the ABC transporter superfamily
AMES_RS41300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AMES_RS41305	COG0601	transmembrane transport
AMES_RS41335	COG0148	phosphopyruvate hydratase activity
AMES_RS41355	COG0672	)-iron permease
AMES_RS41360	COG2822	iron ion transport
AMES_RS41365	COG2837	iron assimilation
AMES_RS41395	COG1131	(ABC) transporter
AMES_RS41445	COG0586	Pfam SNARE associated Golgi protein
AMES_RS41455	COG4585	Histidine kinase
AMES_RS41460	COG2197	response regulator
AMES_RS41465	COG2133	pyrroloquinoline quinone binding
AMES_RS41485	COG1051	belongs to the nudix hydrolase family
AMES_RS41510	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AMES_RS41540	COG0193	aminoacyl-tRNA hydrolase activity
AMES_RS41545	COG3599	regulation of cell shape
AMES_RS41555	COG0318	PFAM AMP-dependent synthetase and ligase
AMES_RS41560	COG0488	(ABC) transporter
AMES_RS41570	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AMES_RS41575	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AMES_RS41580	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AMES_RS41585	COG3583	domain protein
AMES_RS41590	COG0084	hydrolase, TatD family'
AMES_RS41595	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AMES_RS41650	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AMES_RS41655	COG0515	serine threonine protein kinase
AMES_RS41655	COG2815	serine threonine protein kinase
AMES_RS41675	COG2258	MOSC domain
AMES_RS41690	COG1595	DNA-templated transcription, initiation
AMES_RS41735	COG5001	Diguanylate cyclase
AMES_RS41745	COG2124	cytochrome p450
AMES_RS41750	COG1192	Involved in chromosome partitioning
AMES_RS41765	COG0702	epimerase
AMES_RS41775	COG0745	RESPONSE REGULATOR receiver
AMES_RS41780	COG2205	protein histidine kinase activity
AMES_RS41785	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
AMES_RS41790	COG1181	Belongs to the D-alanine--D-alanine ligase family
AMES_RS41800	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AMES_RS41805	COG1733	regulation of RNA biosynthetic process
AMES_RS41810	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AMES_RS41815	COG3433	isochorismatase activity
AMES_RS41815	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AMES_RS41815	COG2226	methyltransferase
AMES_RS41830	COG1280	lysine exporter protein (LysE YggA)
AMES_RS41840	COG0515	serine threonine protein kinase
AMES_RS41895	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AMES_RS41905	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AMES_RS41910	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AMES_RS41935	COG0521	Mo-molybdopterin cofactor biosynthetic process
AMES_RS41935	COG0315	cyclic pyranopterin monophosphate synthase activity
AMES_RS41955	COG5002	protein histidine kinase activity
AMES_RS41960	COG0745	RESPONSE REGULATOR receiver
AMES_RS41980	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AMES_RS41995	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AMES_RS42005	COG1349	DNA-binding transcription factor activity
AMES_RS42010	COG2205	protein histidine kinase activity
AMES_RS42015	COG0745	RESPONSE REGULATOR receiver
AMES_RS42020	COG2860	membrane
AMES_RS42025	COG2197	response regulator
AMES_RS42030	COG2264	protein methyltransferase activity
AMES_RS42040	COG0477	Major facilitator Superfamily
AMES_RS42050	COG0667	Aldo Keto reductase
AMES_RS42055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AMES_RS42070	COG0515	serine threonine protein kinase
AMES_RS42070	COG2815	serine threonine protein kinase
AMES_RS42075	COG0483	inositol monophosphate 1-phosphatase activity
AMES_RS42085	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AMES_RS42100	COG0297	glycogen (starch) synthase activity
AMES_RS42120	COG3285	dna ligase
AMES_RS42120	COG1793	dna ligase
AMES_RS42130	COG0583	DNA-binding transcription factor activity
AMES_RS42140	COG2755	lipolytic protein G-D-S-L family
AMES_RS42140	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AMES_RS42185	COG1960	acyl-CoA dehydrogenase activity
AMES_RS42200	COG0444	Belongs to the ABC transporter superfamily
AMES_RS42205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AMES_RS42210	COG0601	transmembrane transport
AMES_RS42220	COG0747	negative chemotaxis
AMES_RS42250	COG3469	chitinase activity
AMES_RS42260	COG2814	Major facilitator Superfamily
AMES_RS42265	COG4336	lyase activity
AMES_RS42270	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
AMES_RS42275	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AMES_RS42280	COG1984	allophanate hydrolase subunit 2
AMES_RS42320	COG1321	iron dependent repressor
AMES_RS42340	COG1024	Enoyl-CoA hydratase
AMES_RS42345	COG0318	PFAM AMP-dependent synthetase and ligase
AMES_RS42370	COG1169	isochorismate synthase
AMES_RS42385	COG2182	Extracellular solute-binding protein
AMES_RS42390	COG1175	transmembrane transport
AMES_RS42395	COG0395	ABC-type sugar transport system, permease component
AMES_RS42420	COG1595	DNA-templated transcription, initiation
AMES_RS42435	COG0277	FAD linked oxidase domain protein
AMES_RS42460	COG4152	abc transporter atp-binding protein
AMES_RS42475	COG0415	Belongs to the DNA photolyase family
AMES_RS42495	COG1960	acyl-CoA dehydrogenase activity
AMES_RS42520	COG2017	converts alpha-aldose to the beta-anomer
AMES_RS42530	COG1309	transcriptional regulator
AMES_RS42555	COG0259	pyridoxamine-phosphate oxidase activity
AMES_RS42575	COG0829	nickel cation binding
AMES_RS42580	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AMES_RS42590	COG0804	urea catabolic process
AMES_RS42595	COG0832	Belongs to the urease beta subunit family
AMES_RS42600	COG0831	urea catabolic process
AMES_RS42635	COG2197	response regulator
AMES_RS42640	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AMES_RS42655	COG5650	phosphatidylinositol metabolic process
AMES_RS42660	COG1228	amidohydrolase
AMES_RS42665	COG0577	efflux transmembrane transporter activity
AMES_RS42665	COG1136	(ABC) transporter
AMES_RS42670	COG0577	efflux transmembrane transporter activity
AMES_RS42670	COG1136	(ABC) transporter
AMES_RS42685	COG0745	RESPONSE REGULATOR receiver
AMES_RS42690	COG2205	protein histidine kinase activity
AMES_RS42715	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AMES_RS42740	COG2162	N-hydroxyarylamine O-acetyltransferase activity
AMES_RS42745	COG2814	Major facilitator Superfamily
AMES_RS42760	COG2252	PERMEase
AMES_RS42785	COG2814	Major facilitator Superfamily
AMES_RS42795	COG1278	Cold shock
AMES_RS42815	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AMES_RS42820	COG0318	PFAM AMP-dependent synthetase and ligase
AMES_RS42830	COG1595	DNA-templated transcription, initiation
AMES_RS42840	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AMES_RS42880	COG0384	phenazine biosynthesis protein PhzF
AMES_RS42885	COG3304	Inner membrane component domain
AMES_RS42890	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AMES_RS42925	COG1846	Transcriptional regulator
AMES_RS42940	COG1388	LysM domain
AMES_RS42985	COG2018	Roadblock/LC7 domain
AMES_RS43000	COG2018	Roadblock/LC7 domain
AMES_RS43005	COG0642	Histidine kinase
AMES_RS43010	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AMES_RS43015	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AMES_RS43020	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AMES_RS43025	COG1116	anion transmembrane transporter activity
AMES_RS43060	COG3142	Participates in the control of copper homeostasis
AMES_RS43080	COG1061	Type III restriction enzyme res subunit
AMES_RS43100	COG4948	Mandelate Racemase Muconate Lactonizing
AMES_RS43115	COG0459	protein refolding
AMES_RS43125	COG1278	Cold shock
AMES_RS43155	COG2261	transglycosylase associated protein
AMES_RS43165	COG0688	phosphatidylethanolamine metabolic process
AMES_RS43175	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AMES_RS43190	COG0242	peptide deformylase activity
AMES_RS43200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AMES_RS43205	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AMES_RS43210	COG0351	phosphomethylpyrimidine kinase
AMES_RS43230	COG2022	thiamine diphosphate biosynthetic process
AMES_RS43240	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AMES_RS43240	COG2022	thiamine diphosphate biosynthetic process
AMES_RS43245	COG0352	thiamine-phosphate diphosphorylase activity
AMES_RS43255	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AMES_RS43260	COG0477	Major facilitator Superfamily
AMES_RS43270	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AMES_RS43275	COG2971	BadF BadG BcrA BcrD
AMES_RS43285	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AMES_RS43315	COG3903	Transcriptional regulator
AMES_RS43315	COG3629	intracellular signal transduction
AMES_RS43320	COG5285	phytanoyl-CoA dioxygenase
AMES_RS43325	COG1917	Cupin 2, conserved barrel domain protein
AMES_RS43340	COG1752	Esterase of the alpha-beta hydrolase superfamily
AMES_RS43350	COG1733	regulation of RNA biosynthetic process
AMES_RS43355	COG4399	Belongs to the UPF0754 family
AMES_RS43370	COG5416	Lipopolysaccharide assembly protein A domain
AMES_RS43465	COG3971	2-oxopent-4-enoate hydratase activity
AMES_RS43470	COG0346	lactoylglutathione lyase activity
AMES_RS43480	COG1832	CoA-binding protein
AMES_RS43525	COG0745	RESPONSE REGULATOR receiver
AMES_RS43530	COG2205	protein histidine kinase activity
AMES_RS43535	COG1492	cobalamin metabolic process
AMES_RS43540	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AMES_RS43560	COG1620	l-lactate permease
AMES_RS43570	COG4941	Belongs to the sigma-70 factor family
AMES_RS43575	COG3795	YCII-related domain
AMES_RS43580	COG3795	YCII-related domain
AMES_RS43600	COG0642	Histidine kinase
AMES_RS43640	COG1595	DNA-templated transcription, initiation
AMES_RS43680	COG0789	Transcriptional regulator
AMES_RS43710	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AMES_RS43745	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AMES_RS43755	COG1329	Transcriptional regulator
AMES_RS43760	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AMES_RS43765	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AMES_RS43785	COG0215	cysteine-tRNA ligase activity
AMES_RS43825	COG0235	Class ii aldolase
AMES_RS43840	COG4399	Belongs to the UPF0754 family
AMES_RS43845	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AMES_RS43850	COG1121	(ABC) transporter
AMES_RS43855	COG0803	Belongs to the bacterial solute-binding protein 9 family
AMES_RS43860	COG1609	Transcriptional regulator
AMES_RS43895	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AMES_RS43905	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AMES_RS43980	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
AMES_RS43995	COG1396	sequence-specific DNA binding
AMES_RS44030	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AMES_RS44040	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AMES_RS44045	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AMES_RS44050	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AMES_RS44075	COG0789	Transcriptional regulator
AMES_RS44090	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AMES_RS44095	COG0302	gtp cyclohydrolase
AMES_RS44100	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AMES_RS44130	COG0037	tRNA processing
AMES_RS44140	COG2027	D-alanyl-D-alanine carboxypeptidase
AMES_RS44145	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AMES_RS44155	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AMES_RS44160	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AMES_RS44245	COG2188	Transcriptional regulator
AMES_RS44260	COG1674	ftsk spoiiie
AMES_RS44305	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AMES_RS44310	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AMES_RS44340	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AMES_RS44340	COG1754	DNA topoisomerase type I activity
AMES_RS44360	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AMES_RS44365	COG1111	helicase
AMES_RS44365	COG1205	dead DEAH box helicase
AMES_RS44410	COG1472	Belongs to the glycosyl hydrolase 3 family
AMES_RS44415	COG3876	Protein conserved in bacteria
AMES_RS44420	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AMES_RS44425	COG1737	Transcriptional regulator
AMES_RS44430	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AMES_RS44435	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
AMES_RS44445	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AMES_RS44455	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AMES_RS44475	COG3104	oligopeptide transport
AMES_RS44480	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AMES_RS44490	COG0596	Alpha beta hydrolase
AMES_RS44575	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AMES_RS44615	COG2894	cell division
AMES_RS44625	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AMES_RS44635	COG1408	metallophosphoesterase
AMES_RS44645	COG2226	methyltransferase
AMES_RS44680	COG0463	Glycosyl transferase, family 2
AMES_RS44685	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AMES_RS44695	COG2192	nodulation
AMES_RS44710	COG0076	glutamate decarboxylase activity
AMES_RS44715	COG0783	Belongs to the Dps family
AMES_RS44720	COG1764	response to oxidative stress
AMES_RS44730	COG0657	acetylesterase activity
AMES_RS44745	COG2814	Major facilitator Superfamily
AMES_RS44760	COG1690	Belongs to the RtcB family
AMES_RS44825	COG0583	DNA-binding transcription factor activity
AMES_RS44830	COG0697	spore germination
AMES_RS44845	COG3795	YCII-related domain
AMES_RS44850	COG4941	Belongs to the sigma-70 factor family
AMES_RS44855	COG4608	Belongs to the ABC transporter superfamily
AMES_RS44865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AMES_RS44870	COG0601	transmembrane transport
AMES_RS44875	COG0747	negative chemotaxis
AMES_RS44885	COG1216	Glycosyl transferase, family 2
AMES_RS44905	COG1215	transferase activity, transferring glycosyl groups
AMES_RS44915	COG1705	Flagellar rod assembly protein muramidase FlgJ
AMES_RS44920	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AMES_RS44925	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AMES_RS44935	COG1733	regulation of RNA biosynthetic process
AMES_RS44940	COG3467	pyridoxamine 5'-phosphate
AMES_RS44945	COG2801	Transposase and inactivated derivatives
AMES_RS44990	COG1116	anion transmembrane transporter activity
AMES_RS44995	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AMES_RS45005	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AMES_RS45010	COG2205	protein histidine kinase activity
AMES_RS45015	COG0745	RESPONSE REGULATOR receiver
AMES_RS45030	COG2197	response regulator
AMES_RS45050	COG1250	3-hydroxyacyl-CoA dehydrogenase
AMES_RS45055	COG5479	isomerase activity
AMES_RS45055	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AMES_RS45100	COG1674	ftsk spoiiie
AMES_RS45140	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
AMES_RS45145	COG2175	clavaminate synthase activity
AMES_RS45160	COG0702	epimerase
AMES_RS45185	COG1473	amidohydrolase
AMES_RS45200	COG4702	Belongs to the UPF0303 family
AMES_RS45210	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AMES_RS45215	COG0789	Transcriptional regulator
AMES_RS45220	COG0395	ABC-type sugar transport system, permease component
AMES_RS45225	COG1175	transmembrane transport
AMES_RS45240	COG1802	Transcriptional regulator
AMES_RS45270	COG3973	AAA domain
AMES_RS45300	COG0673	inositol 2-dehydrogenase activity
AMES_RS45315	COG3345	alpha-galactosidase
AMES_RS45330	COG2188	Transcriptional regulator
AMES_RS45335	COG1397	ADP-ribosylglycohydrolase
AMES_RS45340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AMES_RS45355	COG0596	Alpha beta hydrolase
AMES_RS45360	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AMES_RS45375	COG1316	TRANSCRIPTIONal
AMES_RS45385	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AMES_RS45390	COG0581	inorganic phosphate transmembrane transporter activity
AMES_RS45400	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AMES_RS45410	COG0745	RESPONSE REGULATOR receiver
AMES_RS45440	COG4044	May play a role in the intracellular transport of hydrophobic ligands
AMES_RS45445	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
AMES_RS45450	COG1984	allophanate hydrolase subunit 2
AMES_RS45500	COG3845	ABC transporter
AMES_RS45535	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AMES_RS45600	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AMES_RS45610	COG1132	(ABC) transporter
AMES_RS45615	COG0047	phosphoribosylformylglycinamidine synthase activity
AMES_RS45620	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AMES_RS45665	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AMES_RS45675	COG1126	abc transporter atp-binding protein
AMES_RS45680	COG0765	amino acid transport
AMES_RS45690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMES_RS45700	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AMES_RS45705	COG4948	Mandelate Racemase Muconate Lactonizing
AMES_RS45720	COG2186	Transcriptional regulator
AMES_RS45745	COG0546	phosphoglycolate phosphatase activity
AMES_RS45760	COG0436	Aminotransferase
AMES_RS45765	COG3953	SLT domain
AMES_RS45765	COG5280	Phage tail tape measure protein TP901
AMES_RS45800	COG0584	glycerophosphoryl diester phosphodiesterase
AMES_RS45825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AMES_RS45835	COG2814	Major facilitator Superfamily
AMES_RS45840	COG0025	NhaP-type Na H and K H
AMES_RS45845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AMES_RS45855	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AMES_RS45925	COG0667	Aldo Keto reductase
AMES_RS45930	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS45980	COG0586	Pfam SNARE associated Golgi protein
AMES_RS45995	COG0277	FAD linked oxidase domain protein
AMES_RS46000	COG3467	pyridoxamine 5'-phosphate
AMES_RS46020	COG0586	Pfam SNARE associated Golgi protein
AMES_RS46035	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS46040	COG0572	uridine kinase
AMES_RS46045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AMES_RS46080	COG0243	molybdopterin cofactor binding
AMES_RS46125	COG1136	(ABC) transporter
AMES_RS46130	COG4221	oxidoreductase activity
AMES_RS46145	COG0542	response to heat
AMES_RS46170	COG0412	Dienelactone hydrolase
AMES_RS46185	COG0789	Transcriptional regulator
AMES_RS46190	COG0484	heat shock protein binding
AMES_RS46195	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AMES_RS46200	COG0443	Heat shock 70 kDa protein
AMES_RS46235	COG0247	lactate metabolic process
AMES_RS46235	COG2181	nitrate reductase activity
AMES_RS46250	COG2340	Cysteine-rich secretory protein family
AMES_RS46290	COG4941	Belongs to the sigma-70 factor family
AMES_RS46295	COG3795	YCII-related domain
AMES_RS46300	COG2124	cytochrome p450
AMES_RS46345	COG3663	DNA glycosylase
AMES_RS46350	COG2197	response regulator
AMES_RS46355	COG1960	acyl-CoA dehydrogenase activity
AMES_RS46365	COG0477	Major facilitator Superfamily
AMES_RS46385	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AMES_RS46410	COG1126	abc transporter atp-binding protein
AMES_RS46435	COG1305	Transglutaminase-like
AMES_RS46450	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AMES_RS46460	COG0022	dehydrogenase e1 component
AMES_RS46465	COG0508	dehydrogenase complex catalyzes the overall conversion of
AMES_RS46490	COG3030	protein affecting phage T7 exclusion by the F plasmid
AMES_RS46530	COG1309	transcriptional regulator
AMES_RS46535	COG2030	dehydratase
AMES_RS46540	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS46545	COG0183	Belongs to the thiolase family
AMES_RS46620	COG1131	(ABC) transporter
AMES_RS46635	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
AMES_RS46650	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AMES_RS46665	COG4585	Histidine kinase
AMES_RS46670	COG2197	response regulator
AMES_RS46675	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS46695	COG1131	(ABC) transporter
AMES_RS46710	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AMES_RS46720	COG1136	(ABC) transporter
AMES_RS46730	COG2197	response regulator
AMES_RS46745	COG0402	S-adenosylhomocysteine deaminase activity
AMES_RS46750	COG4221	oxidoreductase activity
AMES_RS46765	COG2814	Major facilitator Superfamily
AMES_RS46770	COG1846	Transcriptional regulator
AMES_RS46775	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AMES_RS46785	COG1595	DNA-templated transcription, initiation
AMES_RS46795	COG1695	Transcriptional regulator
AMES_RS46805	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AMES_RS46810	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AMES_RS46815	COG0673	inositol 2-dehydrogenase activity
AMES_RS46820	COG1940	carbohydrate kinase activity
AMES_RS46850	COG0360	Binds together with S18 to 16S ribosomal RNA
AMES_RS46860	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AMES_RS46865	COG0359	binds to the 23S rRNA
AMES_RS46905	COG3384	dioxygenase
AMES_RS46930	COG2197	response regulator
AMES_RS46945	COG0477	Major facilitator Superfamily
AMES_RS46950	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AMES_RS46960	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AMES_RS47015	COG1028	Short-chain dehydrogenase reductase Sdr
AMES_RS47020	COG0495	leucyl-tRNA aminoacylation
AMES_RS47100	COG0617	tRNA 3'-terminal CCA addition
AMES_RS47130	COG1595	DNA-templated transcription, initiation
AMES_RS47145	COG3118	belongs to the thioredoxin family
AMES_RS47145	COG0492	ferredoxin-NADP+ reductase activity
AMES_RS47150	COG3409	Peptidoglycan-binding domain 1 protein
AMES_RS47150	COG0860	N-Acetylmuramoyl-L-alanine amidase
AMES_RS47165	COG1181	Belongs to the D-alanine--D-alanine ligase family
AMES_RS47175	COG1192	Involved in chromosome partitioning
AMES_RS47180	COG0357	Ribosomal RNA small subunit methyltransferase G
AMES_RS47195	COG0706	membrane insertase activity
AMES_RS47200	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AMES_RS47225	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMES_RS47240	COG0535	radical SAM domain protein