CU254_RS39370 9264f406c4579226b2783bea1c641fbf 294 Gene3D G3DSA:1.50.10.20 15 287 1.5E-16 T 28-03-2018 CU254_RS39370 9264f406c4579226b2783bea1c641fbf 294 SUPERFAMILY SSF48239 33 142 3.5E-8 T 28-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CU254_RS39370 9264f406c4579226b2783bea1c641fbf 294 SUPERFAMILY SSF48239 236 276 3.5E-8 T 28-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CU254_RS13960 56516ab4b6241cbf114b67c570931e05 947 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 206 347 2.8E-8 T 28-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CU254_RS13960 56516ab4b6241cbf114b67c570931e05 947 SUPERFAMILY SSF52777 735 931 5.0E-5 T 28-03-2018 CU254_RS13960 56516ab4b6241cbf114b67c570931e05 947 Pfam PF06974 Protein of unknown function (DUF1298) 804 945 3.0E-10 T 28-03-2018 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CU254_RS13960 56516ab4b6241cbf114b67c570931e05 947 Gene3D G3DSA:3.40.50.2000 183 350 1.8E-30 T 28-03-2018 CU254_RS13960 56516ab4b6241cbf114b67c570931e05 947 SUPERFAMILY SSF52777 415 525 4.0E-5 T 28-03-2018 CU254_RS13960 56516ab4b6241cbf114b67c570931e05 947 Pfam PF06925 Monogalactosyldiacylglycerol (MGDG) synthase 15 158 2.9E-12 T 28-03-2018 IPR009695 Diacylglycerol glucosyltransferase, N-terminal GO:0009247|GO:0016758 CU254_RS13960 56516ab4b6241cbf114b67c570931e05 947 SUPERFAMILY SSF53756 76 349 3.62E-24 T 28-03-2018 CU254_RS13960 56516ab4b6241cbf114b67c570931e05 947 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 375 527 4.6E-7 T 28-03-2018 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CU254_RS05685 131a1468908e983692e7cf5dab8ace64 131 SUPERFAMILY SSF51182 11 101 8.92E-15 T 28-03-2018 IPR011051 RmlC-like cupin domain CU254_RS05685 131a1468908e983692e7cf5dab8ace64 131 Gene3D G3DSA:2.60.120.10 7 115 3.5E-13 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS20635 0a9c8461f9bf48918b3b144c929a60b6 433 Gene3D G3DSA:3.90.1150.10 311 433 1.9E-33 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS20635 0a9c8461f9bf48918b3b144c929a60b6 433 SUPERFAMILY SSF53383 13 422 6.77E-108 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS20635 0a9c8461f9bf48918b3b144c929a60b6 433 Gene3D G3DSA:3.40.640.10 180 310 1.3E-36 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS20635 0a9c8461f9bf48918b3b144c929a60b6 433 Pfam PF00202 Aminotransferase class-III 24 420 7.9E-86 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CU254_RS20635 0a9c8461f9bf48918b3b144c929a60b6 433 PIRSF PIRSF000521 121 425 4.8E-31 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CU254_RS20635 0a9c8461f9bf48918b3b144c929a60b6 433 PIRSF PIRSF000521 8 130 0.0015 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CU254_RS20635 0a9c8461f9bf48918b3b144c929a60b6 433 Gene3D G3DSA:3.90.1150.10 2 157 2.9E-37 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS21625 8acbdf2b675a299ac99a5c1c4220267e 300 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 11 287 4.4E-77 T 28-03-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 CU254_RS04305 245cf6a237a381c39cd000378e1a459b 985 Gene3D G3DSA:3.40.50.720 55 242 0.38 T 28-03-2018 CU254_RS04305 245cf6a237a381c39cd000378e1a459b 985 Pfam PF12846 AAA-like domain 488 873 2.8E-24 T 28-03-2018 CU254_RS04305 245cf6a237a381c39cd000378e1a459b 985 SUPERFAMILY SSF52540 463 579 3.19E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS04305 245cf6a237a381c39cd000378e1a459b 985 SUPERFAMILY SSF52540 608 825 3.19E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS04305 245cf6a237a381c39cd000378e1a459b 985 Gene3D G3DSA:3.40.50.300 499 826 7.6E-8 T 28-03-2018 CU254_RS36590 05c2994ae0553497d3edcf4e6befc327 290 SUPERFAMILY SSF88659 109 167 6.54E-10 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS36590 05c2994ae0553497d3edcf4e6befc327 290 Pfam PF04542 Sigma-70 region 2 15 78 7.1E-16 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS36590 05c2994ae0553497d3edcf4e6befc327 290 Gene3D G3DSA:3.10.450.50 158 288 8.0E-20 T 28-03-2018 CU254_RS36590 05c2994ae0553497d3edcf4e6befc327 290 Gene3D G3DSA:1.10.1740.10 1 76 4.7E-19 T 28-03-2018 CU254_RS36590 05c2994ae0553497d3edcf4e6befc327 290 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 13 167 2.7E-19 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS36590 05c2994ae0553497d3edcf4e6befc327 290 Gene3D G3DSA:1.10.10.10 77 157 3.2E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS36590 05c2994ae0553497d3edcf4e6befc327 290 SUPERFAMILY SSF54427 177 287 3.47E-13 T 28-03-2018 IPR032710 NTF2-like domain CU254_RS36590 05c2994ae0553497d3edcf4e6befc327 290 Pfam PF08281 Sigma-70, region 4 115 165 5.5E-9 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS36590 05c2994ae0553497d3edcf4e6befc327 290 SUPERFAMILY SSF88946 5 95 6.67E-19 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS21535 14e537e9bcf9aaf74a4c3bce9eddb110 535 Gene3D G3DSA:3.50.50.60 2 396 9.5E-63 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS21535 14e537e9bcf9aaf74a4c3bce9eddb110 535 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 1.9E-42 T 28-03-2018 CU254_RS21535 14e537e9bcf9aaf74a4c3bce9eddb110 535 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 287 302 1.9E-42 T 28-03-2018 CU254_RS21535 14e537e9bcf9aaf74a4c3bce9eddb110 535 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 302 318 1.9E-42 T 28-03-2018 CU254_RS21535 14e537e9bcf9aaf74a4c3bce9eddb110 535 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 338 354 1.9E-42 T 28-03-2018 CU254_RS21535 14e537e9bcf9aaf74a4c3bce9eddb110 535 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 320 338 1.9E-42 T 28-03-2018 CU254_RS21535 14e537e9bcf9aaf74a4c3bce9eddb110 535 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 158 173 1.9E-42 T 28-03-2018 CU254_RS21535 14e537e9bcf9aaf74a4c3bce9eddb110 535 Pfam PF01494 FAD binding domain 3 353 2.0E-93 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CU254_RS21535 14e537e9bcf9aaf74a4c3bce9eddb110 535 SUPERFAMILY SSF51905 4 179 6.7E-62 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS21535 14e537e9bcf9aaf74a4c3bce9eddb110 535 SUPERFAMILY SSF51905 274 365 6.7E-62 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS30100 9ceeb7812cb9e38eced4b7a577a9a8b0 430 SUPERFAMILY SSF48179 215 302 2.89E-25 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CU254_RS30100 9ceeb7812cb9e38eced4b7a577a9a8b0 430 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 19 197 1.2E-34 T 28-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CU254_RS30100 9ceeb7812cb9e38eced4b7a577a9a8b0 430 Gene3D G3DSA:3.40.50.720 12 222 1.8E-31 T 28-03-2018 CU254_RS30100 9ceeb7812cb9e38eced4b7a577a9a8b0 430 Gene3D G3DSA:1.20.5.170 223 235 1.5E-12 T 28-03-2018 CU254_RS30100 9ceeb7812cb9e38eced4b7a577a9a8b0 430 Gene3D G3DSA:1.10.1040.10 236 312 3.7E-26 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CU254_RS30100 9ceeb7812cb9e38eced4b7a577a9a8b0 430 PIRSF PIRSF500136 9 410 2.7E-115 T 28-03-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 CU254_RS30100 9ceeb7812cb9e38eced4b7a577a9a8b0 430 Gene3D G3DSA:3.40.50.720 322 403 1.7E-13 T 28-03-2018 CU254_RS30100 9ceeb7812cb9e38eced4b7a577a9a8b0 430 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 19 402 2.6E-107 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CU254_RS30100 9ceeb7812cb9e38eced4b7a577a9a8b0 430 SUPERFAMILY SSF51735 20 208 1.79E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS30100 9ceeb7812cb9e38eced4b7a577a9a8b0 430 SUPERFAMILY SSF52413 322 425 2.88E-16 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CU254_RS30100 9ceeb7812cb9e38eced4b7a577a9a8b0 430 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 216 302 1.3E-24 T 28-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CU254_RS30100 9ceeb7812cb9e38eced4b7a577a9a8b0 430 PIRSF PIRSF000124 18 398 4.8E-51 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CU254_RS30100 9ceeb7812cb9e38eced4b7a577a9a8b0 430 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 333 379 5.4E-11 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CU254_RS30100 9ceeb7812cb9e38eced4b7a577a9a8b0 430 SMART SM00984 333 425 7.5E-11 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CU254_RS10125 05419432f82b0b4990a9048c3c8e7903 975 SUPERFAMILY SSF52540 131 219 4.32E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS10125 05419432f82b0b4990a9048c3c8e7903 975 SUPERFAMILY SSF52540 253 368 4.32E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS10125 05419432f82b0b4990a9048c3c8e7903 975 SUPERFAMILY SSF48452 618 766 1.9E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS10125 05419432f82b0b4990a9048c3c8e7903 975 PRINTS PR00364 Disease resistance protein signature 253 267 4.7E-6 T 28-03-2018 CU254_RS10125 05419432f82b0b4990a9048c3c8e7903 975 PRINTS PR00364 Disease resistance protein signature 356 370 4.7E-6 T 28-03-2018 CU254_RS10125 05419432f82b0b4990a9048c3c8e7903 975 PRINTS PR00364 Disease resistance protein signature 161 176 4.7E-6 T 28-03-2018 CU254_RS10125 05419432f82b0b4990a9048c3c8e7903 975 SUPERFAMILY SSF47413 53 111 3.75E-11 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS10125 05419432f82b0b4990a9048c3c8e7903 975 Pfam PF13560 Helix-turn-helix domain 57 115 8.1E-11 T 28-03-2018 CU254_RS10125 05419432f82b0b4990a9048c3c8e7903 975 SUPERFAMILY SSF48452 490 597 4.87E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS10125 05419432f82b0b4990a9048c3c8e7903 975 SMART SM00530 57 112 2.0E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS10125 05419432f82b0b4990a9048c3c8e7903 975 Gene3D G3DSA:1.25.40.10 614 973 8.0E-31 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS10125 05419432f82b0b4990a9048c3c8e7903 975 SUPERFAMILY SSF48452 776 966 4.81E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS10125 05419432f82b0b4990a9048c3c8e7903 975 Gene3D G3DSA:1.25.40.10 486 602 8.7E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS10125 05419432f82b0b4990a9048c3c8e7903 975 Gene3D G3DSA:1.10.260.40 44 129 2.4E-15 T 28-03-2018 CU254_RS10125 05419432f82b0b4990a9048c3c8e7903 975 Pfam PF13191 AAA ATPase domain 140 286 1.7E-18 T 28-03-2018 CU254_RS10125 05419432f82b0b4990a9048c3c8e7903 975 SMART SM00028 776 809 3.9 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS10125 05419432f82b0b4990a9048c3c8e7903 975 SMART SM00028 656 689 32.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS10125 05419432f82b0b4990a9048c3c8e7903 975 SMART SM00028 736 769 40.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS10125 05419432f82b0b4990a9048c3c8e7903 975 SMART SM00028 696 729 35.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS10125 05419432f82b0b4990a9048c3c8e7903 975 SMART SM00028 539 572 140.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS10125 05419432f82b0b4990a9048c3c8e7903 975 Gene3D G3DSA:3.40.50.300 140 323 1.3E-8 T 28-03-2018 CU254_RS34225 2abc957e3524aa0230b3dcdc43dbd863 535 Gene3D G3DSA:2.40.10.10 227 326 6.8E-32 T 28-03-2018 CU254_RS34225 2abc957e3524aa0230b3dcdc43dbd863 535 SUPERFAMILY SSF50494 232 446 5.38E-57 T 28-03-2018 IPR009003 Peptidase S1, PA clan CU254_RS34225 2abc957e3524aa0230b3dcdc43dbd863 535 Gene3D G3DSA:2.40.10.10 327 426 2.2E-37 T 28-03-2018 CU254_RS34225 2abc957e3524aa0230b3dcdc43dbd863 535 SMART SM00228 450 521 4.4E-12 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CU254_RS34225 2abc957e3524aa0230b3dcdc43dbd863 535 Pfam PF13365 Trypsin-like peptidase domain 257 401 1.7E-33 T 28-03-2018 CU254_RS34225 2abc957e3524aa0230b3dcdc43dbd863 535 Pfam PF13180 PDZ domain 451 520 2.1E-14 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CU254_RS34225 2abc957e3524aa0230b3dcdc43dbd863 535 SUPERFAMILY SSF50156 421 520 5.39E-17 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CU254_RS34225 2abc957e3524aa0230b3dcdc43dbd863 535 PRINTS PR00834 HtrA/DegQ protease family signature 372 389 5.1E-50 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CU254_RS34225 2abc957e3524aa0230b3dcdc43dbd863 535 PRINTS PR00834 HtrA/DegQ protease family signature 394 411 5.1E-50 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CU254_RS34225 2abc957e3524aa0230b3dcdc43dbd863 535 PRINTS PR00834 HtrA/DegQ protease family signature 290 310 5.1E-50 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CU254_RS34225 2abc957e3524aa0230b3dcdc43dbd863 535 PRINTS PR00834 HtrA/DegQ protease family signature 266 278 5.1E-50 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CU254_RS34225 2abc957e3524aa0230b3dcdc43dbd863 535 PRINTS PR00834 HtrA/DegQ protease family signature 479 491 5.1E-50 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CU254_RS34225 2abc957e3524aa0230b3dcdc43dbd863 535 PRINTS PR00834 HtrA/DegQ protease family signature 331 355 5.1E-50 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CU254_RS34225 2abc957e3524aa0230b3dcdc43dbd863 535 Gene3D G3DSA:2.30.42.10 427 527 4.2E-16 T 28-03-2018 CU254_RS18030 520c603ed4b17a66d809582f6fb1e6fe 153 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 2 151 31.619 T 28-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CU254_RS18030 520c603ed4b17a66d809582f6fb1e6fe 153 Gene3D G3DSA:3.40.1280.10 1 152 5.6E-34 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CU254_RS18030 520c603ed4b17a66d809582f6fb1e6fe 153 Pfam PF00588 SpoU rRNA Methylase family 2 142 1.1E-29 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CU254_RS18030 520c603ed4b17a66d809582f6fb1e6fe 153 SUPERFAMILY SSF75217 1 150 1.24E-39 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CU254_RS18030 520c603ed4b17a66d809582f6fb1e6fe 153 PIRSF PIRSF029256 1 152 1.2E-58 T 28-03-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 KEGG: 00260+2.1.1.20|MetaCyc: PWY-6004 CU254_RS10130 baac659f6966ca642ec287df0dabc533 184 Gene3D G3DSA:3.30.420.10 3 181 4.4E-27 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS10130 baac659f6966ca642ec287df0dabc533 184 SUPERFAMILY SSF53098 5 178 1.1E-25 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS10130 baac659f6966ca642ec287df0dabc533 184 Pfam PF00929 Exonuclease 7 169 8.1E-13 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CU254_RS10130 baac659f6966ca642ec287df0dabc533 184 SMART SM00479 4 181 2.7E-4 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CU254_RS15595 c3ea93ce9bf4b689d487a3b569a38fa6 101 SUPERFAMILY SSF55961 1 53 1.51E-8 T 28-03-2018 CU254_RS15595 c3ea93ce9bf4b689d487a3b569a38fa6 101 Gene3D G3DSA:3.30.530.20 1 89 2.6E-9 T 28-03-2018 IPR023393 START-like domain CU254_RS17635 67e8f26eb27e0d6cecac32520e8dacc2 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 13 71 1.9E-15 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS17635 67e8f26eb27e0d6cecac32520e8dacc2 308 SUPERFAMILY SSF46785 12 94 6.12E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS17635 67e8f26eb27e0d6cecac32520e8dacc2 308 Gene3D G3DSA:1.10.10.10 6 93 3.1E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS17635 67e8f26eb27e0d6cecac32520e8dacc2 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 49 3.2E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS17635 67e8f26eb27e0d6cecac32520e8dacc2 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 28 39 3.2E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS17635 67e8f26eb27e0d6cecac32520e8dacc2 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 49 60 3.2E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS17635 67e8f26eb27e0d6cecac32520e8dacc2 308 Pfam PF03466 LysR substrate binding domain 100 301 4.1E-33 T 28-03-2018 IPR005119 LysR, substrate-binding CU254_RS17635 67e8f26eb27e0d6cecac32520e8dacc2 308 Gene3D G3DSA:3.40.190.10 192 272 8.6E-18 T 28-03-2018 CU254_RS17635 67e8f26eb27e0d6cecac32520e8dacc2 308 SUPERFAMILY SSF53850 100 304 1.23E-35 T 28-03-2018 CU254_RS17635 67e8f26eb27e0d6cecac32520e8dacc2 308 Gene3D G3DSA:3.40.190.10 102 191 3.0E-21 T 28-03-2018 CU254_RS03260 d82639f14e4e128e6f9201cbeaa811ea 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 40 4.3E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS03260 d82639f14e4e128e6f9201cbeaa811ea 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 71 4.3E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS03260 d82639f14e4e128e6f9201cbeaa811ea 203 SUPERFAMILY SSF46689 19 75 4.99E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS03260 d82639f14e4e128e6f9201cbeaa811ea 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 29 73 4.7E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS03260 d82639f14e4e128e6f9201cbeaa811ea 203 Pfam PF16859 Bacterial transcriptional repressor C-terminal 84 195 3.1E-31 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS03260 d82639f14e4e128e6f9201cbeaa811ea 203 Gene3D G3DSA:1.10.357.10 72 203 1.9E-25 T 28-03-2018 CU254_RS03260 d82639f14e4e128e6f9201cbeaa811ea 203 Gene3D G3DSA:1.10.10.60 2 71 1.8E-16 T 28-03-2018 CU254_RS03260 d82639f14e4e128e6f9201cbeaa811ea 203 SUPERFAMILY SSF48498 85 200 6.4E-25 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS27295 de2190d1115778c6fa40cc070c78af9b 274 Gene3D G3DSA:1.10.10.10 133 273 1.1E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS27295 de2190d1115778c6fa40cc070c78af9b 274 SUPERFAMILY SSF46785 169 264 5.57E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS23425 5cf5b63364f22830824cb24dc87f6443 861 SUPERFAMILY SSF51905 344 523 4.21E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS23425 5cf5b63364f22830824cb24dc87f6443 861 SUPERFAMILY SSF51905 32 242 4.21E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS23425 5cf5b63364f22830824cb24dc87f6443 861 SUPERFAMILY SSF53474 594 836 8.88E-75 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS23425 5cf5b63364f22830824cb24dc87f6443 861 Pfam PF07859 alpha/beta hydrolase fold 633 837 3.7E-72 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CU254_RS23425 5cf5b63364f22830824cb24dc87f6443 861 Gene3D G3DSA:3.50.50.60 29 193 1.7E-34 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS23425 5cf5b63364f22830824cb24dc87f6443 861 SUPERFAMILY SSF51905 172 404 2.43E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS23425 5cf5b63364f22830824cb24dc87f6443 861 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 35 238 1.0E-15 T 28-03-2018 CU254_RS23425 5cf5b63364f22830824cb24dc87f6443 861 ProSitePatterns PS01174 Lipolytic enzymes "G-D-X-G" family, putative serine active site. 705 717 - T 28-03-2018 IPR033140 Lipase, GDXG, putative serine active site CU254_RS23425 5cf5b63364f22830824cb24dc87f6443 861 Gene3D G3DSA:3.40.50.1820 558 861 3.1E-63 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS23425 5cf5b63364f22830824cb24dc87f6443 861 Gene3D G3DSA:3.50.50.60 194 557 1.2E-56 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS23425 5cf5b63364f22830824cb24dc87f6443 861 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 33 55 3.2E-7 T 28-03-2018 CU254_RS23425 5cf5b63364f22830824cb24dc87f6443 861 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 203 228 3.2E-7 T 28-03-2018 CU254_RS23425 5cf5b63364f22830824cb24dc87f6443 861 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 161 170 3.2E-7 T 28-03-2018 CU254_RS34955 7ae26762047a085f611869d8ae34a296 228 PIRSF PIRSF009467 3 228 1.4E-32 T 28-03-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 CU254_RS34955 7ae26762047a085f611869d8ae34a296 228 Pfam PF01730 UreF 33 179 1.3E-17 T 28-03-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 CU254_RS28265 9296d8567033daef50d01e4da0169a8f 259 SUPERFAMILY SSF102588 3 228 1.23E-53 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CU254_RS28265 9296d8567033daef50d01e4da0169a8f 259 Pfam PF02585 GlcNAc-PI de-N-acetylase 7 146 5.9E-27 T 28-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 CU254_RS28265 9296d8567033daef50d01e4da0169a8f 259 Gene3D G3DSA:3.40.50.10320 1 259 2.7E-64 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CU254_RS13430 cc823aec38f09002bfcfcb972bc87c6b 228 Pfam PF00392 Bacterial regulatory proteins, gntR family 1 58 1.0E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS13430 cc823aec38f09002bfcfcb972bc87c6b 228 SMART SM00866 78 218 9.0E-31 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CU254_RS13430 cc823aec38f09002bfcfcb972bc87c6b 228 Gene3D G3DSA:3.40.1410.10 59 226 4.1E-41 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CU254_RS13430 cc823aec38f09002bfcfcb972bc87c6b 228 SMART SM00345 1 58 1.6E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS13430 cc823aec38f09002bfcfcb972bc87c6b 228 SUPERFAMILY SSF64288 46 225 5.65E-43 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CU254_RS13430 cc823aec38f09002bfcfcb972bc87c6b 228 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 32 48 1.4E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS13430 cc823aec38f09002bfcfcb972bc87c6b 228 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 18 32 1.4E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS13430 cc823aec38f09002bfcfcb972bc87c6b 228 SUPERFAMILY SSF46785 1 62 7.8E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS13430 cc823aec38f09002bfcfcb972bc87c6b 228 Gene3D G3DSA:1.10.10.10 1 58 5.1E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS13430 cc823aec38f09002bfcfcb972bc87c6b 228 Pfam PF07702 UTRA domain 82 217 3.5E-34 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CU254_RS07485 76efb4a1b190a649f8595e0ac75c6372 338 Gene3D G3DSA:1.10.3470.10 47 331 2.4E-34 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CU254_RS07485 76efb4a1b190a649f8595e0ac75c6372 338 Pfam PF02653 Branched-chain amino acid transport system / permease component 53 326 7.4E-41 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CU254_RS37105 19ca9ae213925deef8903c079879b1fa 687 SUPERFAMILY SSF52540 31 221 4.53E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS37105 19ca9ae213925deef8903c079879b1fa 687 Gene3D G3DSA:1.20.272.10 245 367 3.6E-22 T 28-03-2018 CU254_RS37105 19ca9ae213925deef8903c079879b1fa 687 Gene3D G3DSA:1.10.8.60 168 244 7.9E-8 T 28-03-2018 CU254_RS37105 19ca9ae213925deef8903c079879b1fa 687 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 4 362 9.9E-113 T 28-03-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 CU254_RS37105 19ca9ae213925deef8903c079879b1fa 687 Pfam PF13177 DNA polymerase III, delta subunit 19 177 4.0E-39 T 28-03-2018 CU254_RS37105 19ca9ae213925deef8903c079879b1fa 687 SUPERFAMILY SSF48019 246 363 2.3E-23 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CU254_RS37105 19ca9ae213925deef8903c079879b1fa 687 Gene3D G3DSA:3.40.50.300 2 167 3.7E-37 T 28-03-2018 CU254_RS37105 19ca9ae213925deef8903c079879b1fa 687 SMART SM00382 36 180 2.2E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS37105 19ca9ae213925deef8903c079879b1fa 687 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 239 369 1.8E-18 T 28-03-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 CU254_RS17920 64ea0473a2d736922cbda46bbbab39eb 398 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 21 112 3.4E-15 T 28-03-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CU254_RS17920 64ea0473a2d736922cbda46bbbab39eb 398 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 58 72 2.9E-6 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CU254_RS17920 64ea0473a2d736922cbda46bbbab39eb 398 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 189 209 2.9E-6 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CU254_RS17920 64ea0473a2d736922cbda46bbbab39eb 398 SMART SM00839 161 389 6.9E-44 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CU254_RS17920 64ea0473a2d736922cbda46bbbab39eb 398 Gene3D G3DSA:3.40.50.10860 5 150 3.5E-31 T 28-03-2018 CU254_RS17920 64ea0473a2d736922cbda46bbbab39eb 398 SUPERFAMILY SSF53223 8 122 3.84E-26 T 28-03-2018 CU254_RS17920 64ea0473a2d736922cbda46bbbab39eb 398 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 156 324 1.2E-35 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CU254_RS17920 64ea0473a2d736922cbda46bbbab39eb 398 SUPERFAMILY SSF51735 156 377 6.23E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS17920 64ea0473a2d736922cbda46bbbab39eb 398 Gene3D G3DSA:3.40.50.720 156 391 1.3E-38 T 28-03-2018 CU254_RS17920 64ea0473a2d736922cbda46bbbab39eb 398 PIRSF PIRSF000185 3 392 5.1E-78 T 28-03-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 CU254_RS17920 64ea0473a2d736922cbda46bbbab39eb 398 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 66 79 - T 28-03-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CU254_RS10980 3420ec59288a64044374801b11f3a516 317 PIRSF PIRSF036979 14 314 3.5E-108 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 CU254_RS10980 3420ec59288a64044374801b11f3a516 317 SUPERFAMILY SSF52768 16 313 5.22E-101 T 28-03-2018 CU254_RS10980 3420ec59288a64044374801b11f3a516 317 ProSitePatterns PS01053 Arginase family signature. 239 260 - T 28-03-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 CU254_RS10980 3420ec59288a64044374801b11f3a516 317 TIGRFAM TIGR01230 agmatinase: agmatinase 35 308 3.8E-70 T 28-03-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 CU254_RS10980 3420ec59288a64044374801b11f3a516 317 Pfam PF00491 Arginase family 36 307 3.3E-92 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 CU254_RS10980 3420ec59288a64044374801b11f3a516 317 Gene3D G3DSA:3.40.800.10 7 316 6.7E-106 T 28-03-2018 CU254_RS10980 3420ec59288a64044374801b11f3a516 317 PRINTS PR00116 Arginase signature 123 138 9.5E-14 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 CU254_RS10980 3420ec59288a64044374801b11f3a516 317 PRINTS PR00116 Arginase signature 236 265 9.5E-14 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 CU254_RS15895 2c80121500fe40db6e85f10eeec9b000 274 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 21 255 7.4E-55 T 28-03-2018 CU254_RS15895 2c80121500fe40db6e85f10eeec9b000 274 SUPERFAMILY SSF51735 15 258 2.49E-74 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS15895 2c80121500fe40db6e85f10eeec9b000 274 Gene3D G3DSA:3.40.50.720 49 267 7.4E-61 T 28-03-2018 CU254_RS15895 2c80121500fe40db6e85f10eeec9b000 274 Gene3D G3DSA:3.40.50.720 12 48 0.0011 T 28-03-2018 CU254_RS15895 2c80121500fe40db6e85f10eeec9b000 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 1.3E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS15895 2c80121500fe40db6e85f10eeec9b000 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 155 1.3E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS15895 2c80121500fe40db6e85f10eeec9b000 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 186 203 1.3E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS15895 2c80121500fe40db6e85f10eeec9b000 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 91 102 1.3E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS15895 2c80121500fe40db6e85f10eeec9b000 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 1.3E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS15895 2c80121500fe40db6e85f10eeec9b000 274 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 184 1.3E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS15895 2c80121500fe40db6e85f10eeec9b000 274 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 91 102 3.7E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS15895 2c80121500fe40db6e85f10eeec9b000 274 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 153 3.7E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS15895 2c80121500fe40db6e85f10eeec9b000 274 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 165 184 3.7E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS15895 2c80121500fe40db6e85f10eeec9b000 274 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 152 180 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS38915 5611298f72d5d47f3d07d6a37e427276 521 Pfam PF09594 Glycosyltransferase family 87 175 405 1.3E-13 T 28-03-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 CU254_RS38915 5611298f72d5d47f3d07d6a37e427276 521 PIRSF PIRSF010361 26 506 4.3E-157 T 28-03-2018 IPR016570 Uncharacterised conserved protein UCP010361, membrane CU254_RS31000 f3db71b0db3b429b6c844d0c68f1b093 350 Pfam PF03576 Peptidase family S58 17 332 3.4E-71 T 28-03-2018 IPR005321 Peptidase S58, DmpA CU254_RS31000 f3db71b0db3b429b6c844d0c68f1b093 350 SUPERFAMILY SSF56266 16 341 8.5E-71 T 28-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CU254_RS31000 f3db71b0db3b429b6c844d0c68f1b093 350 Gene3D G3DSA:3.60.70.12 9 343 8.0E-108 T 28-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CU254_RS30160 96bc9cc0b96313e2859faffe6472b004 158 Pfam PF02310 B12 binding domain 20 133 1.3E-10 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CU254_RS30160 96bc9cc0b96313e2859faffe6472b004 158 Gene3D G3DSA:3.40.50.280 12 148 4.8E-24 T 28-03-2018 CU254_RS30160 96bc9cc0b96313e2859faffe6472b004 158 SUPERFAMILY SSF52242 19 137 5.49E-15 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CU254_RS30485 828f1e29f9b6dec2a2c884ed99c71603 306 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 9 249 6.4E-47 T 28-03-2018 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 CU254_RS30485 828f1e29f9b6dec2a2c884ed99c71603 306 Pfam PF04072 Leucine carboxyl methyltransferase 11 184 2.9E-41 T 28-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CU254_RS30485 828f1e29f9b6dec2a2c884ed99c71603 306 SUPERFAMILY SSF53335 7 251 8.58E-52 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS30485 828f1e29f9b6dec2a2c884ed99c71603 306 Gene3D G3DSA:3.40.50.150 2 267 2.0E-39 T 28-03-2018 CU254_RS28085 a1e069f08527a79186bd3538b432f352 288 SUPERFAMILY SSF53474 1 282 1.36E-62 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS28085 a1e069f08527a79186bd3538b432f352 288 Pfam PF12146 Serine aminopeptidase, S33 24 269 1.6E-15 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 CU254_RS28085 a1e069f08527a79186bd3538b432f352 288 Gene3D G3DSA:3.40.50.1820 3 288 9.8E-52 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS14165 df2d2a7c81a9c092108eef02b69b49b1 138 Pfam PF12802 MarR family 25 82 2.8E-11 T 28-03-2018 CU254_RS14165 df2d2a7c81a9c092108eef02b69b49b1 138 SUPERFAMILY SSF46785 5 129 2.09E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS14165 df2d2a7c81a9c092108eef02b69b49b1 138 SMART SM00347 19 118 5.3E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS14165 df2d2a7c81a9c092108eef02b69b49b1 138 Gene3D G3DSA:1.10.10.10 2 132 3.9E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS14165 df2d2a7c81a9c092108eef02b69b49b1 138 ProSitePatterns PS01117 MarR-type HTH domain signature. 56 91 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CU254_RS29820 2a9dbfc7f803fa8afdddea4f99d501e0 375 Gene3D G3DSA:3.40.710.10 1 373 4.3E-83 T 28-03-2018 CU254_RS29820 2a9dbfc7f803fa8afdddea4f99d501e0 375 SUPERFAMILY SSF56601 4 369 2.97E-83 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CU254_RS29820 2a9dbfc7f803fa8afdddea4f99d501e0 375 Pfam PF00144 Beta-lactamase 6 355 1.2E-67 T 28-03-2018 IPR001466 Beta-lactamase-related CU254_RS02250 ea63efee3c4b2663515b2281ac11ce62 477 SUPERFAMILY SSF53067 235 427 5.36E-38 T 28-03-2018 CU254_RS02250 ea63efee3c4b2663515b2281ac11ce62 477 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 240 423 2.4E-22 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CU254_RS02250 ea63efee3c4b2663515b2281ac11ce62 477 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 6 231 6.0E-47 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CU254_RS02250 ea63efee3c4b2663515b2281ac11ce62 477 Gene3D G3DSA:3.30.420.40 241 458 2.0E-44 T 28-03-2018 CU254_RS02250 ea63efee3c4b2663515b2281ac11ce62 477 PIRSF PIRSF000538 3 458 3.9E-80 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CU254_RS02250 ea63efee3c4b2663515b2281ac11ce62 477 SUPERFAMILY SSF53067 5 233 6.12E-51 T 28-03-2018 CU254_RS02250 ea63efee3c4b2663515b2281ac11ce62 477 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 123 135 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CU254_RS02250 ea63efee3c4b2663515b2281ac11ce62 477 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 335 356 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CU254_RS02250 ea63efee3c4b2663515b2281ac11ce62 477 TIGRFAM TIGR01312 XylB: xylulokinase 8 426 2.1E-124 T 28-03-2018 IPR006000 Xylulokinase GO:0004856|GO:0005997 KEGG: 00040+2.7.1.17 CU254_RS02250 ea63efee3c4b2663515b2281ac11ce62 477 Gene3D G3DSA:3.30.420.40 1 240 1.4E-66 T 28-03-2018 CU254_RS39330 86ac8c39254194ea66260b478b23a799 663 Gene3D G3DSA:3.40.50.300 500 661 1.8E-15 T 28-03-2018 CU254_RS39330 86ac8c39254194ea66260b478b23a799 663 SUPERFAMILY SSF52540 421 651 1.47E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS39330 86ac8c39254194ea66260b478b23a799 663 SUPERFAMILY SSF52540 158 311 1.47E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS39330 86ac8c39254194ea66260b478b23a799 663 Pfam PF13538 UvrD-like helicase C-terminal domain 603 646 1.1E-6 T 28-03-2018 IPR027785 UvrD-like helicase C-terminal domain CU254_RS39330 86ac8c39254194ea66260b478b23a799 663 Gene3D G3DSA:3.40.50.300 164 494 1.8E-26 T 28-03-2018 CU254_RS39330 86ac8c39254194ea66260b478b23a799 663 Pfam PF13245 AAA domain 174 476 1.3E-6 T 28-03-2018 CU254_RS02385 551d5b4cf41d1d7aba6867c7945ae1f5 214 Gene3D G3DSA:1.10.357.10 82 202 2.1E-23 T 28-03-2018 CU254_RS02385 551d5b4cf41d1d7aba6867c7945ae1f5 214 Gene3D G3DSA:1.10.10.60 1 36 7.1E-11 T 28-03-2018 CU254_RS02385 551d5b4cf41d1d7aba6867c7945ae1f5 214 SUPERFAMILY SSF48498 81 196 1.3E-28 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS02385 551d5b4cf41d1d7aba6867c7945ae1f5 214 SUPERFAMILY SSF46689 1 75 1.03E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS02385 551d5b4cf41d1d7aba6867c7945ae1f5 214 Gene3D G3DSA:1.10.260.40 37 81 2.8E-8 T 28-03-2018 CU254_RS02385 551d5b4cf41d1d7aba6867c7945ae1f5 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 61 1.5E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS16655 35002dbcbd25a260205531eaeb18ba2f 793 Gene3D G3DSA:2.40.40.20 638 792 2.2E-17 T 28-03-2018 CU254_RS16655 35002dbcbd25a260205531eaeb18ba2f 793 SUPERFAMILY SSF53706 90 667 1.3E-132 T 28-03-2018 CU254_RS16655 35002dbcbd25a260205531eaeb18ba2f 793 Gene3D G3DSA:3.40.50.740 370 637 8.7E-44 T 28-03-2018 CU254_RS16655 35002dbcbd25a260205531eaeb18ba2f 793 TIGRFAM TIGR01701 Fdhalpha-like: oxidoreductase alpha (molybdopterin) subunit 55 791 1.8E-260 T 28-03-2018 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 CU254_RS16655 35002dbcbd25a260205531eaeb18ba2f 793 Pfam PF00384 Molybdopterin oxidoreductase 152 450 3.1E-25 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS16655 35002dbcbd25a260205531eaeb18ba2f 793 SUPERFAMILY SSF50692 676 792 6.56E-12 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain CU254_RS16655 35002dbcbd25a260205531eaeb18ba2f 793 Gene3D G3DSA:3.40.50.740 153 369 3.3E-36 T 28-03-2018 CU254_RS16655 35002dbcbd25a260205531eaeb18ba2f 793 Pfam PF01568 Molydopterin dinucleotide binding domain 678 768 1.6E-6 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CU254_RS16655 35002dbcbd25a260205531eaeb18ba2f 793 PIRSF PIRSF000144 36 793 0.0 T 28-03-2018 CU254_RS32715 4468b703e61c3052ebcd89936d4bac8e 355 SUPERFAMILY SSF53850 38 350 5.93E-50 T 28-03-2018 CU254_RS32715 4468b703e61c3052ebcd89936d4bac8e 355 Pfam PF13343 Bacterial extracellular solute-binding protein 90 312 1.9E-26 T 28-03-2018 CU254_RS32715 4468b703e61c3052ebcd89936d4bac8e 355 Gene3D G3DSA:3.40.190.10 166 351 8.5E-29 T 28-03-2018 CU254_RS32715 4468b703e61c3052ebcd89936d4bac8e 355 TIGRFAM TIGR01254 sfuA: ABC transporter periplasmic binding protein, thiB subfamily 40 349 4.2E-68 T 28-03-2018 IPR005948 Thiamine/thiamin pyrophosphate-binding periplasmic protein, ABC transporter GO:0015888|GO:0030288|GO:0030975 CU254_RS32715 4468b703e61c3052ebcd89936d4bac8e 355 Gene3D G3DSA:3.40.190.10 39 165 1.0E-13 T 28-03-2018 CU254_RS15110 4880d596457c0300b7fce357c3e3ceef 423 Gene3D G3DSA:2.60.120.330 7 423 7.1E-113 T 28-03-2018 IPR027443 Isopenicillin N synthase-like CU254_RS15110 4880d596457c0300b7fce357c3e3ceef 423 SUPERFAMILY SSF51197 7 422 6.68E-135 T 28-03-2018 CU254_RS15110 4880d596457c0300b7fce357c3e3ceef 423 Pfam PF07350 Protein of unknown function (DUF1479) 15 421 1.8E-123 T 28-03-2018 IPR010856 Protein of unknown function DUF1479 CU254_RS20370 6f9cfe8fcacf9c9e9534c6679fbe71bc 201 Gene3D G3DSA:1.10.357.10 68 195 3.5E-14 T 28-03-2018 CU254_RS20370 6f9cfe8fcacf9c9e9534c6679fbe71bc 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 68 1.7E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS20370 6f9cfe8fcacf9c9e9534c6679fbe71bc 201 SUPERFAMILY SSF46689 13 85 1.03E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS20370 6f9cfe8fcacf9c9e9534c6679fbe71bc 201 Gene3D G3DSA:1.10.10.60 3 67 2.0E-14 T 28-03-2018 CU254_RS09155 8fb1b1c10660748da4c4830359fa0c34 223 SUPERFAMILY SSF52172 13 139 2.13E-19 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS09155 8fb1b1c10660748da4c4830359fa0c34 223 SMART SM00421 154 211 4.7E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS09155 8fb1b1c10660748da4c4830359fa0c34 223 Pfam PF00072 Response regulator receiver domain 15 123 1.7E-14 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS09155 8fb1b1c10660748da4c4830359fa0c34 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 187 199 2.1E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS09155 8fb1b1c10660748da4c4830359fa0c34 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 187 2.1E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS09155 8fb1b1c10660748da4c4830359fa0c34 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 171 2.1E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS09155 8fb1b1c10660748da4c4830359fa0c34 223 Pfam PF00196 Bacterial regulatory proteins, luxR family 156 207 7.8E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS09155 8fb1b1c10660748da4c4830359fa0c34 223 SUPERFAMILY SSF46894 147 217 5.44E-16 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS09155 8fb1b1c10660748da4c4830359fa0c34 223 Gene3D G3DSA:3.40.50.2300 7 126 3.8E-18 T 28-03-2018 CU254_RS09155 8fb1b1c10660748da4c4830359fa0c34 223 Gene3D G3DSA:1.10.10.10 127 221 3.1E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS09155 8fb1b1c10660748da4c4830359fa0c34 223 SMART SM00448 13 123 6.9E-15 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS28340 c6afb17013cf33f8720bc42fea780b12 396 SUPERFAMILY SSF48264 22 396 9.43E-93 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS28340 c6afb17013cf33f8720bc42fea780b12 396 Gene3D G3DSA:1.10.630.10 2 396 7.8E-78 T 28-03-2018 CU254_RS28340 c6afb17013cf33f8720bc42fea780b12 396 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 341 350 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CU254_RS28340 c6afb17013cf33f8720bc42fea780b12 396 Pfam PF00067 Cytochrome P450 41 364 8.8E-22 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS28340 c6afb17013cf33f8720bc42fea780b12 396 PRINTS PR00385 P450 superfamily signature 348 359 1.2E-7 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS28340 c6afb17013cf33f8720bc42fea780b12 396 PRINTS PR00385 P450 superfamily signature 339 348 1.2E-7 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS28340 c6afb17013cf33f8720bc42fea780b12 396 PRINTS PR00385 P450 superfamily signature 236 253 1.2E-7 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS28340 c6afb17013cf33f8720bc42fea780b12 396 PRINTS PR00385 P450 superfamily signature 271 282 1.2E-7 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS28340 c6afb17013cf33f8720bc42fea780b12 396 PRINTS PR00359 B-class P450 signature 135 151 1.9E-57 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS28340 c6afb17013cf33f8720bc42fea780b12 396 PRINTS PR00359 B-class P450 signature 271 282 1.9E-57 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS28340 c6afb17013cf33f8720bc42fea780b12 396 PRINTS PR00359 B-class P450 signature 318 333 1.9E-57 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS28340 c6afb17013cf33f8720bc42fea780b12 396 PRINTS PR00359 B-class P450 signature 190 212 1.9E-57 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS28340 c6afb17013cf33f8720bc42fea780b12 396 PRINTS PR00359 B-class P450 signature 290 317 1.9E-57 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS28340 c6afb17013cf33f8720bc42fea780b12 396 PRINTS PR00359 B-class P450 signature 88 99 1.9E-57 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS28340 c6afb17013cf33f8720bc42fea780b12 396 PRINTS PR00359 B-class P450 signature 152 167 1.9E-57 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS28340 c6afb17013cf33f8720bc42fea780b12 396 PRINTS PR00359 B-class P450 signature 339 348 1.9E-57 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS28340 c6afb17013cf33f8720bc42fea780b12 396 PRINTS PR00359 B-class P450 signature 348 359 1.9E-57 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS29305 9aa587a27f5da5d1041e9c0c6b2e6a0f 302 Pfam PF04072 Leucine carboxyl methyltransferase 21 199 2.2E-58 T 28-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CU254_RS29305 9aa587a27f5da5d1041e9c0c6b2e6a0f 302 SUPERFAMILY SSF53335 17 299 3.53E-72 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS29305 9aa587a27f5da5d1041e9c0c6b2e6a0f 302 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 19 278 2.4E-76 T 28-03-2018 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 CU254_RS29305 9aa587a27f5da5d1041e9c0c6b2e6a0f 302 Gene3D G3DSA:3.40.50.150 2 279 2.4E-51 T 28-03-2018 CU254_RS38575 cd7cf48ba12cd5e2507c0acf8cec270e 330 Pfam PF02780 Transketolase, C-terminal domain 202 320 2.8E-33 T 28-03-2018 IPR033248 Transketolase, C-terminal domain CU254_RS38575 cd7cf48ba12cd5e2507c0acf8cec270e 330 SUPERFAMILY SSF52518 6 186 1.77E-62 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS38575 cd7cf48ba12cd5e2507c0acf8cec270e 330 SUPERFAMILY SSF52922 202 327 4.32E-33 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CU254_RS38575 cd7cf48ba12cd5e2507c0acf8cec270e 330 Pfam PF02779 Transketolase, pyrimidine binding domain 6 181 3.6E-42 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CU254_RS38575 cd7cf48ba12cd5e2507c0acf8cec270e 330 Gene3D G3DSA:3.40.50.920 200 329 1.8E-30 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CU254_RS38575 cd7cf48ba12cd5e2507c0acf8cec270e 330 SMART SM00861 7 182 1.4E-62 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CU254_RS38575 cd7cf48ba12cd5e2507c0acf8cec270e 330 Gene3D G3DSA:3.40.50.970 3 198 1.5E-56 T 28-03-2018 CU254_RS08030 e2a02ea1433914265b5d874f53613909 307 Pfam PF00589 Phage integrase family 118 292 5.1E-45 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CU254_RS08030 e2a02ea1433914265b5d874f53613909 307 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 7 307 53.881 T 28-03-2018 IPR023009 Tyrosine recombinase XerC/XerD CU254_RS08030 e2a02ea1433914265b5d874f53613909 307 Gene3D G3DSA:1.10.150.130 5 117 6.1E-19 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CU254_RS08030 e2a02ea1433914265b5d874f53613909 307 SUPERFAMILY SSF47823 9 104 3.53E-11 T 28-03-2018 IPR010998 Integrase, Lambda-type, N-terminal CU254_RS08030 e2a02ea1433914265b5d874f53613909 307 SUPERFAMILY SSF56349 115 305 7.06E-50 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CU254_RS08030 e2a02ea1433914265b5d874f53613909 307 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 10 95 1.9E-14 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CU254_RS08030 e2a02ea1433914265b5d874f53613909 307 Gene3D G3DSA:1.10.443.10 118 301 1.7E-46 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CU254_RS31505 48911a20136624188951f13465c9d0a9 465 ProSitePatterns PS00217 Sugar transport proteins signature 2. 152 177 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CU254_RS31505 48911a20136624188951f13465c9d0a9 465 Gene3D G3DSA:1.20.1250.20 249 463 4.1E-29 T 28-03-2018 CU254_RS31505 48911a20136624188951f13465c9d0a9 465 Pfam PF07690 Major Facilitator Superfamily 83 396 1.1E-34 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS31505 48911a20136624188951f13465c9d0a9 465 Gene3D G3DSA:1.20.1250.20 34 248 1.5E-26 T 28-03-2018 CU254_RS31505 48911a20136624188951f13465c9d0a9 465 SUPERFAMILY SSF103473 31 455 5.36E-71 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS21895 306dcd784488d6dfb0aa80a3383a5660 220 Gene3D G3DSA:3.90.226.10 3 218 1.8E-40 T 28-03-2018 CU254_RS21895 306dcd784488d6dfb0aa80a3383a5660 220 Pfam PF00378 Enoyl-CoA hydratase/isomerase 19 207 2.7E-24 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CU254_RS21895 306dcd784488d6dfb0aa80a3383a5660 220 SUPERFAMILY SSF52096 7 217 4.1E-43 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS14325 a348e113e4ddd4f8142685fa4e62ffab 194 SUPERFAMILY SSF54427 7 113 1.43E-10 T 28-03-2018 IPR032710 NTF2-like domain CU254_RS14325 a348e113e4ddd4f8142685fa4e62ffab 194 Gene3D G3DSA:3.10.450.50 2 114 2.4E-9 T 28-03-2018 CU254_RS22500 8ca1df6c1278d2a1439973a1588c6966 64 SUPERFAMILY SSF143034 2 63 6.02E-21 T 28-03-2018 CU254_RS22500 8ca1df6c1278d2a1439973a1588c6966 64 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 63 6.3E-23 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CU254_RS22500 8ca1df6c1278d2a1439973a1588c6966 64 Pfam PF01632 Ribosomal protein L35 2 62 4.7E-23 T 28-03-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS22500 8ca1df6c1278d2a1439973a1588c6966 64 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 17.622 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CU254_RS22500 8ca1df6c1278d2a1439973a1588c6966 64 PRINTS PR00064 Ribosomal protein L35 signature 3 20 6.4E-16 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CU254_RS22500 8ca1df6c1278d2a1439973a1588c6966 64 PRINTS PR00064 Ribosomal protein L35 signature 21 35 6.4E-16 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CU254_RS22500 8ca1df6c1278d2a1439973a1588c6966 64 PRINTS PR00064 Ribosomal protein L35 signature 36 54 6.4E-16 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CU254_RS29035 f4275e401cec6270b9e1fdaa5767bec5 282 Gene3D G3DSA:3.90.25.10 138 277 6.4E-4 T 28-03-2018 CU254_RS29035 f4275e401cec6270b9e1fdaa5767bec5 282 Pfam PF05368 NmrA-like family 4 212 5.6E-21 T 28-03-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 CU254_RS29035 f4275e401cec6270b9e1fdaa5767bec5 282 Gene3D G3DSA:3.40.50.720 1 137 3.2E-24 T 28-03-2018 CU254_RS29035 f4275e401cec6270b9e1fdaa5767bec5 282 SUPERFAMILY SSF51735 3 248 2.46E-54 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS22575 1c08fec053c0843fb80123f853beab7c 461 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 278 414 7.5E-23 T 28-03-2018 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822 CU254_RS22575 1c08fec053c0843fb80123f853beab7c 461 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 97 274 1.5E-61 T 28-03-2018 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822 CU254_RS22575 1c08fec053c0843fb80123f853beab7c 461 Gene3D G3DSA:3.20.20.80 87 446 1.2E-109 T 28-03-2018 CU254_RS22575 1c08fec053c0843fb80123f853beab7c 461 PRINTS PR00738 Glycosyl hydrolase family 20 signature 120 141 1.6E-40 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CU254_RS22575 1c08fec053c0843fb80123f853beab7c 461 PRINTS PR00738 Glycosyl hydrolase family 20 signature 396 413 1.6E-40 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CU254_RS22575 1c08fec053c0843fb80123f853beab7c 461 PRINTS PR00738 Glycosyl hydrolase family 20 signature 48 68 1.6E-40 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CU254_RS22575 1c08fec053c0843fb80123f853beab7c 461 PRINTS PR00738 Glycosyl hydrolase family 20 signature 239 257 1.6E-40 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CU254_RS22575 1c08fec053c0843fb80123f853beab7c 461 PRINTS PR00738 Glycosyl hydrolase family 20 signature 378 394 1.6E-40 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CU254_RS22575 1c08fec053c0843fb80123f853beab7c 461 PRINTS PR00738 Glycosyl hydrolase family 20 signature 91 108 1.6E-40 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CU254_RS22575 1c08fec053c0843fb80123f853beab7c 461 PRINTS PR00738 Glycosyl hydrolase family 20 signature 191 208 1.6E-40 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CU254_RS22575 1c08fec053c0843fb80123f853beab7c 461 PRINTS PR00738 Glycosyl hydrolase family 20 signature 261 274 1.6E-40 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CU254_RS22575 1c08fec053c0843fb80123f853beab7c 461 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 29 94 6.5E-13 T 28-03-2018 IPR015882 Beta-hexosaminidase, bacteial type, N-terminal KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822 CU254_RS22575 1c08fec053c0843fb80123f853beab7c 461 Gene3D G3DSA:3.30.379.10 25 86 7.7E-15 T 28-03-2018 CU254_RS22575 1c08fec053c0843fb80123f853beab7c 461 SUPERFAMILY SSF55545 7 96 4.04E-17 T 28-03-2018 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CU254_RS22575 1c08fec053c0843fb80123f853beab7c 461 SUPERFAMILY SSF51445 97 426 1.9E-95 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS26960 b3c990489e4d6d4208741096613ca106 247 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS26960 b3c990489e4d6d4208741096613ca106 247 SUPERFAMILY SSF51735 3 245 3.43E-64 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS26960 b3c990489e4d6d4208741096613ca106 247 Gene3D G3DSA:3.40.50.720 2 36 1.7E-6 T 28-03-2018 CU254_RS26960 b3c990489e4d6d4208741096613ca106 247 Gene3D G3DSA:3.40.50.720 37 247 1.1E-51 T 28-03-2018 CU254_RS26960 b3c990489e4d6d4208741096613ca106 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 2.1E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS26960 b3c990489e4d6d4208741096613ca106 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 2.1E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS26960 b3c990489e4d6d4208741096613ca106 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 2.1E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS26960 b3c990489e4d6d4208741096613ca106 247 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 7 242 1.6E-48 T 28-03-2018 CU254_RS26960 b3c990489e4d6d4208741096613ca106 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 19 2.0E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS26960 b3c990489e4d6d4208741096613ca106 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 2.0E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS26960 b3c990489e4d6d4208741096613ca106 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 2.0E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS26960 b3c990489e4d6d4208741096613ca106 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 2.0E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS26960 b3c990489e4d6d4208741096613ca106 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 2.0E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS26960 b3c990489e4d6d4208741096613ca106 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 2.0E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18910 a47346b684ec89f00400b87a10085718 402 Gene3D G3DSA:3.40.50.720 2 146 3.5E-23 T 28-03-2018 CU254_RS18910 a47346b684ec89f00400b87a10085718 402 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 12 140 4.6E-13 T 28-03-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 CU254_RS18910 a47346b684ec89f00400b87a10085718 402 Gene3D G3DSA:3.40.50.720 210 399 0.25 T 28-03-2018 CU254_RS18910 a47346b684ec89f00400b87a10085718 402 SUPERFAMILY SSF51735 10 168 1.0E-15 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS15980 b19d41f2a3b4837e5e7af3e0cb2ddb7a 746 Pfam PF00069 Protein kinase domain 9 250 2.0E-43 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CU254_RS15980 b19d41f2a3b4837e5e7af3e0cb2ddb7a 746 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 15 38 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 CU254_RS15980 b19d41f2a3b4837e5e7af3e0cb2ddb7a 746 Gene3D G3DSA:3.30.565.40 358 481 1.9E-4 T 28-03-2018 CU254_RS15980 b19d41f2a3b4837e5e7af3e0cb2ddb7a 746 Gene3D G3DSA:3.30.200.20 5 93 7.2E-21 T 28-03-2018 CU254_RS15980 b19d41f2a3b4837e5e7af3e0cb2ddb7a 746 Gene3D G3DSA:1.10.510.10 94 292 1.7E-40 T 28-03-2018 CU254_RS15980 b19d41f2a3b4837e5e7af3e0cb2ddb7a 746 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 128 140 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CU254_RS15980 b19d41f2a3b4837e5e7af3e0cb2ddb7a 746 SUPERFAMILY SSF56112 7 257 1.16E-64 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS27970 c3906f2292e599fab0440c3039def619 307 Gene3D G3DSA:1.10.10.10 2 57 2.9E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS27970 c3906f2292e599fab0440c3039def619 307 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 67 4.1E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS27970 c3906f2292e599fab0440c3039def619 307 SUPERFAMILY SSF48498 148 296 9.56E-19 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS27970 c3906f2292e599fab0440c3039def619 307 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 143 295 1.2E-14 T 28-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 CU254_RS27970 c3906f2292e599fab0440c3039def619 307 Gene3D G3DSA:1.10.10.60 58 136 2.1E-13 T 28-03-2018 CU254_RS27970 c3906f2292e599fab0440c3039def619 307 SUPERFAMILY SSF46689 78 139 9.23E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS27970 c3906f2292e599fab0440c3039def619 307 Gene3D G3DSA:1.10.357.10 142 305 3.1E-29 T 28-03-2018 CU254_RS27970 c3906f2292e599fab0440c3039def619 307 SUPERFAMILY SSF46785 3 71 8.86E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS27970 c3906f2292e599fab0440c3039def619 307 SMART SM00345 10 67 1.1E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS18300 396b353a471f8f2a86e4c7bb4f3a5b39 296 SMART SM00046 4 130 4.9E-4 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CU254_RS18300 396b353a471f8f2a86e4c7bb4f3a5b39 296 Gene3D G3DSA:3.40.50.10330 4 133 2.9E-26 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 CU254_RS18300 396b353a471f8f2a86e4c7bb4f3a5b39 296 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 6 295 3.1E-38 T 28-03-2018 IPR005218 Diacylglycerol/lipid kinase CU254_RS18300 396b353a471f8f2a86e4c7bb4f3a5b39 296 SUPERFAMILY SSF111331 4 295 2.62E-69 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain CU254_RS18300 396b353a471f8f2a86e4c7bb4f3a5b39 296 Pfam PF00781 Diacylglycerol kinase catalytic domain 7 129 5.8E-22 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CU254_RS21820 f9ed29208c2619c2adab83b4528ddad8 166 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 4 72 5.6E-7 T 28-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CU254_RS21820 f9ed29208c2619c2adab83b4528ddad8 166 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 126 132 - T 28-03-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CU254_RS21820 f9ed29208c2619c2adab83b4528ddad8 166 SUPERFAMILY SSF53155 5 80 7.85E-17 T 28-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CU254_RS21820 f9ed29208c2619c2adab83b4528ddad8 166 SUPERFAMILY SSF46767 75 156 1.44E-30 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CU254_RS21820 f9ed29208c2619c2adab83b4528ddad8 166 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 77 155 1.5E-33 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CU254_RS21820 f9ed29208c2619c2adab83b4528ddad8 166 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 77 155 7.9E-32 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CU254_RS21820 f9ed29208c2619c2adab83b4528ddad8 166 Gene3D G3DSA:3.30.160.70 1 73 3.6E-21 T 28-03-2018 CU254_RS21820 f9ed29208c2619c2adab83b4528ddad8 166 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 7 156 41.688 T 28-03-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 CU254_RS21820 f9ed29208c2619c2adab83b4528ddad8 166 Gene3D G3DSA:1.10.10.10 74 165 4.0E-33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS17190 a442e55356ea263026fcb7fc8619b9e1 228 Gene3D G3DSA:2.102.10.10 120 228 9.8E-18 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CU254_RS17190 a442e55356ea263026fcb7fc8619b9e1 228 Pfam PF00355 Rieske [2Fe-2S] domain 123 198 2.7E-13 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CU254_RS17190 a442e55356ea263026fcb7fc8619b9e1 228 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 76 105 1.4E-4 T 28-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal CU254_RS17190 a442e55356ea263026fcb7fc8619b9e1 228 SUPERFAMILY SSF50022 87 223 5.5E-23 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CU254_RS29495 a3130ce57b79344a4834e37e03c997f8 326 Pfam PF00676 Dehydrogenase E1 component 13 315 2.1E-65 T 28-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 CU254_RS29495 a3130ce57b79344a4834e37e03c997f8 326 SUPERFAMILY SSF52518 7 324 1.48E-82 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS29495 a3130ce57b79344a4834e37e03c997f8 326 Gene3D G3DSA:3.40.50.970 1 326 4.2E-72 T 28-03-2018 CU254_RS34260 912b0581d026c4bb9b7d25c9ca2b7686 385 SUPERFAMILY SSF103473 7 382 1.74E-22 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS34260 912b0581d026c4bb9b7d25c9ca2b7686 385 Gene3D G3DSA:1.20.1250.20 196 383 1.3E-12 T 28-03-2018 CU254_RS34260 912b0581d026c4bb9b7d25c9ca2b7686 385 Gene3D G3DSA:1.20.1250.20 1 195 2.6E-10 T 28-03-2018 CU254_RS26500 c163541a4c4a6f91faf52eda86527b6a 497 Gene3D G3DSA:3.40.309.10 263 460 5.9E-67 T 28-03-2018 CU254_RS26500 c163541a4c4a6f91faf52eda86527b6a 497 SUPERFAMILY SSF53720 4 483 5.63E-153 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CU254_RS26500 c163541a4c4a6f91faf52eda86527b6a 497 Gene3D G3DSA:3.40.605.10 1 262 1.3E-87 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CU254_RS26500 c163541a4c4a6f91faf52eda86527b6a 497 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 6 481 6.1E-213 T 28-03-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373|Reactome: R-HSA-70895 CU254_RS26500 c163541a4c4a6f91faf52eda86527b6a 497 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 274 285 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CU254_RS26500 c163541a4c4a6f91faf52eda86527b6a 497 Pfam PF00171 Aldehyde dehydrogenase family 18 477 1.6E-145 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CU254_RS19960 1e6ddcaffc390a253627c8d59625038d 202 Gene3D G3DSA:1.10.357.10 75 193 7.4E-5 T 28-03-2018 CU254_RS19960 1e6ddcaffc390a253627c8d59625038d 202 SUPERFAMILY SSF48498 80 192 2.74E-7 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS19960 1e6ddcaffc390a253627c8d59625038d 202 SUPERFAMILY SSF46689 3 86 5.99E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS19960 1e6ddcaffc390a253627c8d59625038d 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 1.8E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS19960 1e6ddcaffc390a253627c8d59625038d 202 Gene3D G3DSA:1.10.10.60 47 74 1.2E-7 T 28-03-2018 CU254_RS19960 1e6ddcaffc390a253627c8d59625038d 202 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 82 194 2.6E-9 T 28-03-2018 CU254_RS19960 1e6ddcaffc390a253627c8d59625038d 202 Gene3D G3DSA:1.10.10.60 1 46 3.5E-15 T 28-03-2018 CU254_RS36060 924a95fe41b0691c1f38a7802ca9a060 264 SUPERFAMILY SSF100950 83 240 1.99E-23 T 28-03-2018 CU254_RS36060 924a95fe41b0691c1f38a7802ca9a060 264 Pfam PF08220 DeoR-like helix-turn-helix domain 14 67 2.2E-13 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CU254_RS36060 924a95fe41b0691c1f38a7802ca9a060 264 Gene3D G3DSA:3.40.50.1360 81 247 5.5E-30 T 28-03-2018 CU254_RS36060 924a95fe41b0691c1f38a7802ca9a060 264 SUPERFAMILY SSF46785 12 74 5.91E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS36060 924a95fe41b0691c1f38a7802ca9a060 264 SMART SM01134 81 241 6.4E-52 T 28-03-2018 CU254_RS36060 924a95fe41b0691c1f38a7802ca9a060 264 ProSitePatterns PS00894 DeoR-type HTH domain signature. 14 48 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CU254_RS36060 924a95fe41b0691c1f38a7802ca9a060 264 SMART SM00420 14 66 2.1E-12 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CU254_RS36060 924a95fe41b0691c1f38a7802ca9a060 264 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 46 64 1.2E-6 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CU254_RS36060 924a95fe41b0691c1f38a7802ca9a060 264 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 32 46 1.2E-6 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CU254_RS36060 924a95fe41b0691c1f38a7802ca9a060 264 Pfam PF00455 DeoR C terminal sensor domain 83 240 7.4E-42 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain CU254_RS36060 924a95fe41b0691c1f38a7802ca9a060 264 Gene3D G3DSA:1.10.10.10 9 67 1.2E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS31710 64e7f697ddc3d115bde3f7a3bb032b12 221 Pfam PF00072 Response regulator receiver domain 6 117 7.3E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS31710 64e7f697ddc3d115bde3f7a3bb032b12 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 192 204 8.8E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS31710 64e7f697ddc3d115bde3f7a3bb032b12 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 176 8.8E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS31710 64e7f697ddc3d115bde3f7a3bb032b12 221 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 192 8.8E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS31710 64e7f697ddc3d115bde3f7a3bb032b12 221 SUPERFAMILY SSF46894 150 217 3.74E-19 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS31710 64e7f697ddc3d115bde3f7a3bb032b12 221 Gene3D G3DSA:3.40.50.2300 3 128 2.4E-35 T 28-03-2018 CU254_RS31710 64e7f697ddc3d115bde3f7a3bb032b12 221 SMART SM00421 159 216 6.3E-20 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS31710 64e7f697ddc3d115bde3f7a3bb032b12 221 Gene3D G3DSA:1.10.10.10 129 220 3.6E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS31710 64e7f697ddc3d115bde3f7a3bb032b12 221 SUPERFAMILY SSF52172 3 133 3.27E-32 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS31710 64e7f697ddc3d115bde3f7a3bb032b12 221 Pfam PF00196 Bacterial regulatory proteins, luxR family 161 215 2.0E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS31710 64e7f697ddc3d115bde3f7a3bb032b12 221 ProSitePatterns PS00622 LuxR-type HTH domain signature. 176 203 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS31710 64e7f697ddc3d115bde3f7a3bb032b12 221 SMART SM00448 4 117 2.5E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS07650 076b203dfccfa61ee14a6901259815d8 260 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS07650 076b203dfccfa61ee14a6901259815d8 260 Pfam PF00005 ABC transporter 20 174 7.9E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS07650 076b203dfccfa61ee14a6901259815d8 260 SUPERFAMILY SSF52540 4 229 3.92E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS07650 076b203dfccfa61ee14a6901259815d8 260 SMART SM00382 29 222 2.6E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS07650 076b203dfccfa61ee14a6901259815d8 260 Gene3D G3DSA:3.40.50.300 1 248 2.3E-52 T 28-03-2018 CU254_RS20580 5d78bfc0f88747bfdf619cf51a3d3c85 191 Gene3D G3DSA:1.10.10.10 1 92 2.6E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS20580 5d78bfc0f88747bfdf619cf51a3d3c85 191 Pfam PF10400 Virulence activator alpha C-term 92 179 5.0E-20 T 28-03-2018 IPR018309 Transcription regulator PadR, C-terminal CU254_RS20580 5d78bfc0f88747bfdf619cf51a3d3c85 191 SUPERFAMILY SSF46785 2 181 9.67E-39 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS20580 5d78bfc0f88747bfdf619cf51a3d3c85 191 Pfam PF03551 Transcriptional regulator PadR-like family 7 81 2.3E-14 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CU254_RS00560 724c21e86d1e2d119f824dd789550878 67 SMART SM00357 3 67 1.4E-29 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 CU254_RS00560 724c21e86d1e2d119f824dd789550878 67 PRINTS PR00050 Cold shock protein signature 4 19 2.3E-16 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CU254_RS00560 724c21e86d1e2d119f824dd789550878 67 PRINTS PR00050 Cold shock protein signature 25 34 2.3E-16 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CU254_RS00560 724c21e86d1e2d119f824dd789550878 67 PRINTS PR00050 Cold shock protein signature 40 58 2.3E-16 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CU254_RS00560 724c21e86d1e2d119f824dd789550878 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 5.7E-31 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CU254_RS00560 724c21e86d1e2d119f824dd789550878 67 Gene3D G3DSA:2.40.50.140 1 67 1.7E-30 T 28-03-2018 CU254_RS00560 724c21e86d1e2d119f824dd789550878 67 SUPERFAMILY SSF50249 1 66 1.26E-25 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CU254_RS00560 724c21e86d1e2d119f824dd789550878 67 PIRSF PIRSF002599 1 67 6.7E-25 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 CU254_RS00560 724c21e86d1e2d119f824dd789550878 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 28-03-2018 IPR019844 Cold-shock conserved site CU254_RS34180 a23a03236af6a66985e3b119073233fb 293 SUPERFAMILY SSF56281 7 276 2.03E-39 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS34180 a23a03236af6a66985e3b119073233fb 293 Pfam PF00753 Metallo-beta-lactamase superfamily 56 256 3.1E-20 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS34180 a23a03236af6a66985e3b119073233fb 293 Gene3D G3DSA:3.60.15.10 15 281 1.8E-38 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS34180 a23a03236af6a66985e3b119073233fb 293 SMART SM00849 53 269 1.2E-16 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS37520 d607706a9d30bbeea57dc991004d665b 373 PIRSF PIRSF006487 22 369 1.2E-18 T 28-03-2018 CU254_RS37520 d607706a9d30bbeea57dc991004d665b 373 Pfam PF01571 Aminomethyltransferase folate-binding domain 25 251 2.6E-25 T 28-03-2018 IPR006222 Glycine cleavage T-protein-like, N-terminal CU254_RS37520 d607706a9d30bbeea57dc991004d665b 373 SUPERFAMILY SSF103025 25 276 1.88E-51 T 28-03-2018 CU254_RS37520 d607706a9d30bbeea57dc991004d665b 373 Gene3D G3DSA:2.40.30.110 276 353 3.0E-8 T 28-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CU254_RS37520 d607706a9d30bbeea57dc991004d665b 373 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 224 287 2.0E-15 T 28-03-2018 IPR017703 YgfZ/GcvT conserved site CU254_RS37520 d607706a9d30bbeea57dc991004d665b 373 Gene3D G3DSA:3.30.70.1400 52 274 3.1E-28 T 28-03-2018 CU254_RS37520 d607706a9d30bbeea57dc991004d665b 373 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 261 351 1.5E-5 T 28-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CU254_RS09845 f44e750230e8d7eb1aba3506698e7ba0 213 SUPERFAMILY SSF52172 3 181 2.26E-33 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS09845 f44e750230e8d7eb1aba3506698e7ba0 213 Gene3D G3DSA:3.40.50.2300 2 134 2.5E-37 T 28-03-2018 CU254_RS09845 f44e750230e8d7eb1aba3506698e7ba0 213 SMART SM00448 3 116 8.2E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS09845 f44e750230e8d7eb1aba3506698e7ba0 213 Gene3D G3DSA:1.10.10.10 135 211 4.8E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS09845 f44e750230e8d7eb1aba3506698e7ba0 213 SMART SM00421 149 206 4.2E-24 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS09845 f44e750230e8d7eb1aba3506698e7ba0 213 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 206 2.4E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS09845 f44e750230e8d7eb1aba3506698e7ba0 213 ProSitePatterns PS00622 LuxR-type HTH domain signature. 166 193 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS09845 f44e750230e8d7eb1aba3506698e7ba0 213 Pfam PF00072 Response regulator receiver domain 7 116 7.3E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS09845 f44e750230e8d7eb1aba3506698e7ba0 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 166 2.3E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS09845 f44e750230e8d7eb1aba3506698e7ba0 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 194 2.3E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS09845 f44e750230e8d7eb1aba3506698e7ba0 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 182 2.3E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS01825 4703810fefe50b6a8d7308c3a4f8e91b 1303 Pfam PF04998 RNA polymerase Rpb1, domain 5 832 1200 3.8E-63 T 28-03-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CU254_RS01825 4703810fefe50b6a8d7308c3a4f8e91b 1303 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 10 1253 0.0 T 28-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CU254_RS01825 4703810fefe50b6a8d7308c3a4f8e91b 1303 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 4 1263 17.427 T 28-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CU254_RS01825 4703810fefe50b6a8d7308c3a4f8e91b 1303 SMART SM00663 310 589 7.3E-170 T 28-03-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CU254_RS01825 4703810fefe50b6a8d7308c3a4f8e91b 1303 Gene3D G3DSA:2.40.50.100 976 1101 2.9E-34 T 28-03-2018 CU254_RS01825 4703810fefe50b6a8d7308c3a4f8e91b 1303 Pfam PF05000 RNA polymerase Rpb1, domain 4 762 817 3.5E-8 T 28-03-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CU254_RS01825 4703810fefe50b6a8d7308c3a4f8e91b 1303 Pfam PF04983 RNA polymerase Rpb1, domain 3 564 725 1.2E-24 T 28-03-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CU254_RS01825 4703810fefe50b6a8d7308c3a4f8e91b 1303 Pfam PF04997 RNA polymerase Rpb1, domain 1 7 417 2.5E-81 T 28-03-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CU254_RS01825 4703810fefe50b6a8d7308c3a4f8e91b 1303 SUPERFAMILY SSF64484 5 1254 0.0 T 28-03-2018 CU254_RS01825 4703810fefe50b6a8d7308c3a4f8e91b 1303 Pfam PF00623 RNA polymerase Rpb1, domain 2 419 560 1.7E-35 T 28-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CU254_RS01825 4703810fefe50b6a8d7308c3a4f8e91b 1303 Gene3D G3DSA:2.40.40.20 421 563 2.4E-39 T 28-03-2018 CU254_RS36600 2f05086b921867ed261e3b670f9e48f0 219 SUPERFAMILY SSF48498 113 212 1.07E-10 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS36600 2f05086b921867ed261e3b670f9e48f0 219 Gene3D G3DSA:1.10.357.10 31 219 6.2E-36 T 28-03-2018 CU254_RS36600 2f05086b921867ed261e3b670f9e48f0 219 Pfam PF00440 Bacterial regulatory proteins, tetR family 48 93 1.9E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS36600 2f05086b921867ed261e3b670f9e48f0 219 SUPERFAMILY SSF46689 38 107 3.31E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS36600 2f05086b921867ed261e3b670f9e48f0 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 68 91 1.2E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS36600 2f05086b921867ed261e3b670f9e48f0 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 61 1.2E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS27310 14077a2c7d88019ee005ce44629582f3 164 Pfam PF04978 Protein of unknown function (DUF664) 14 154 3.1E-42 T 28-03-2018 IPR007061 Protein of unknown function DUF664 CU254_RS27310 14077a2c7d88019ee005ce44629582f3 164 SUPERFAMILY SSF109854 9 154 9.92E-33 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CU254_RS27310 14077a2c7d88019ee005ce44629582f3 164 Gene3D G3DSA:1.20.120.450 3 160 6.8E-28 T 28-03-2018 CU254_RS36540 71882044f29de9cc606202b02384cf68 379 Gene3D G3DSA:3.30.450.90 53 158 2.3E-31 T 28-03-2018 CU254_RS36540 71882044f29de9cc606202b02384cf68 379 TIGRFAM TIGR03819 heli_sec_ATPase: helicase/secretion neighborhood ATPase 5 345 4.0E-144 T 28-03-2018 IPR022399 Helicase/secretion neighbourhood ATPase CU254_RS36540 71882044f29de9cc606202b02384cf68 379 Gene3D G3DSA:3.40.50.300 159 340 3.1E-13 T 28-03-2018 CU254_RS36540 71882044f29de9cc606202b02384cf68 379 SUPERFAMILY SSF52540 45 340 5.4E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS36540 71882044f29de9cc606202b02384cf68 379 Pfam PF00437 Type II/IV secretion system protein 57 335 9.0E-69 T 28-03-2018 IPR001482 Type II secretion system protein E GO:0005524|GO:0006810 CU254_RS28400 ff9b4e67cb9e3a9fd935d2200c05b66d 483 SUPERFAMILY SSF46548 6 153 1.26E-36 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CU254_RS28400 ff9b4e67cb9e3a9fd935d2200c05b66d 483 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 472 3.7E-213 T 28-03-2018 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 CU254_RS28400 ff9b4e67cb9e3a9fd935d2200c05b66d 483 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 144 454 4.4E-29 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS28400 ff9b4e67cb9e3a9fd935d2200c05b66d 483 Gene3D G3DSA:3.50.50.60 403 478 4.3E-9 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS28400 ff9b4e67cb9e3a9fd935d2200c05b66d 483 Gene3D G3DSA:3.40.50.720 140 235 3.9E-20 T 28-03-2018 CU254_RS28400 ff9b4e67cb9e3a9fd935d2200c05b66d 483 Gene3D G3DSA:1.10.1060.10 3 139 9.6E-41 T 28-03-2018 CU254_RS28400 ff9b4e67cb9e3a9fd935d2200c05b66d 483 Gene3D G3DSA:3.50.50.60 236 327 1.1E-24 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS28400 ff9b4e67cb9e3a9fd935d2200c05b66d 483 Gene3D G3DSA:3.50.50.60 329 399 3.8E-4 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS28400 ff9b4e67cb9e3a9fd935d2200c05b66d 483 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 26 131 3.0E-22 T 28-03-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 CU254_RS28400 ff9b4e67cb9e3a9fd935d2200c05b66d 483 PRINTS PR00419 Adrenodoxin reductase family signature 210 220 6.4E-24 T 28-03-2018 CU254_RS28400 ff9b4e67cb9e3a9fd935d2200c05b66d 483 PRINTS PR00419 Adrenodoxin reductase family signature 145 167 6.4E-24 T 28-03-2018 CU254_RS28400 ff9b4e67cb9e3a9fd935d2200c05b66d 483 PRINTS PR00419 Adrenodoxin reductase family signature 284 298 6.4E-24 T 28-03-2018 CU254_RS28400 ff9b4e67cb9e3a9fd935d2200c05b66d 483 PRINTS PR00419 Adrenodoxin reductase family signature 168 181 6.4E-24 T 28-03-2018 CU254_RS28400 ff9b4e67cb9e3a9fd935d2200c05b66d 483 SUPERFAMILY SSF51971 142 399 9.42E-67 T 28-03-2018 CU254_RS17700 d80f6205d7cd3194977e5f81db7d7bbe 527 Gene3D G3DSA:3.40.50.300 272 527 4.0E-72 T 28-03-2018 CU254_RS17700 d80f6205d7cd3194977e5f81db7d7bbe 527 Gene3D G3DSA:3.40.50.300 1 271 2.0E-66 T 28-03-2018 CU254_RS17700 d80f6205d7cd3194977e5f81db7d7bbe 527 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 495 520 0.052 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CU254_RS17700 d80f6205d7cd3194977e5f81db7d7bbe 527 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 231 267 0.0019 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CU254_RS17700 d80f6205d7cd3194977e5f81db7d7bbe 527 SUPERFAMILY SSF52540 1 251 1.11E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS17700 d80f6205d7cd3194977e5f81db7d7bbe 527 ProSitePatterns PS00211 ABC transporters family signature. 416 430 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS17700 d80f6205d7cd3194977e5f81db7d7bbe 527 SMART SM00382 304 493 7.4E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS17700 d80f6205d7cd3194977e5f81db7d7bbe 527 SMART SM00382 30 229 2.7E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS17700 d80f6205d7cd3194977e5f81db7d7bbe 527 Pfam PF00005 ABC transporter 296 443 1.0E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS17700 d80f6205d7cd3194977e5f81db7d7bbe 527 Pfam PF00005 ABC transporter 22 180 1.8E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS17700 d80f6205d7cd3194977e5f81db7d7bbe 527 SUPERFAMILY SSF52540 274 515 2.51E-70 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS03335 16efb3fc712e6126ad33c9f5af317347 269 SUPERFAMILY SSF55681 19 202 5.59E-40 T 28-03-2018 CU254_RS03335 16efb3fc712e6126ad33c9f5af317347 269 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 22 265 6.0E-37 T 28-03-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 CU254_RS03335 16efb3fc712e6126ad33c9f5af317347 269 SUPERFAMILY SSF50037 221 265 2.01E-6 T 28-03-2018 IPR008988 Transcriptional repressor, C-terminal CU254_RS03335 16efb3fc712e6126ad33c9f5af317347 269 Pfam PF02237 Biotin protein ligase C terminal domain 218 265 2.7E-6 T 28-03-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 CU254_RS03335 16efb3fc712e6126ad33c9f5af317347 269 Gene3D G3DSA:3.30.930.10 1 217 3.2E-54 T 28-03-2018 CU254_RS03335 16efb3fc712e6126ad33c9f5af317347 269 Gene3D G3DSA:2.30.30.100 218 267 1.4E-16 T 28-03-2018 CU254_RS03335 16efb3fc712e6126ad33c9f5af317347 269 Pfam PF03099 Biotin/lipoate A/B protein ligase family 31 139 1.3E-8 T 28-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CU254_RS03750 2e0553c4257b1cdaecced4db6a296544 396 SUPERFAMILY SSF103473 6 385 4.58E-55 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS03750 2e0553c4257b1cdaecced4db6a296544 396 Gene3D G3DSA:1.20.1250.20 203 391 1.4E-18 T 28-03-2018 CU254_RS03750 2e0553c4257b1cdaecced4db6a296544 396 Pfam PF00083 Sugar (and other) transporter 242 377 1.6E-5 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CU254_RS03750 2e0553c4257b1cdaecced4db6a296544 396 Pfam PF07690 Major Facilitator Superfamily 13 227 1.2E-25 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS03750 2e0553c4257b1cdaecced4db6a296544 396 Gene3D G3DSA:1.20.1250.20 3 193 1.1E-29 T 28-03-2018 CU254_RS03750 2e0553c4257b1cdaecced4db6a296544 396 ProSitePatterns PS00216 Sugar transport proteins signature 1. 62 78 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CU254_RS39450 8c8b6ce066efa5f4703cf4f4a4724d4d 218 Pfam PF00072 Response regulator receiver domain 8 120 9.9E-16 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS39450 8c8b6ce066efa5f4703cf4f4a4724d4d 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 196 2.6E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS39450 8c8b6ce066efa5f4703cf4f4a4724d4d 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 184 2.6E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS39450 8c8b6ce066efa5f4703cf4f4a4724d4d 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 168 2.6E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS39450 8c8b6ce066efa5f4703cf4f4a4724d4d 218 SUPERFAMILY SSF52172 4 137 1.85E-21 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS39450 8c8b6ce066efa5f4703cf4f4a4724d4d 218 SMART SM00448 5 124 2.3E-11 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS39450 8c8b6ce066efa5f4703cf4f4a4724d4d 218 SMART SM00421 151 214 6.4E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS39450 8c8b6ce066efa5f4703cf4f4a4724d4d 218 SUPERFAMILY SSF46894 145 199 1.53E-15 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS39450 8c8b6ce066efa5f4703cf4f4a4724d4d 218 Gene3D G3DSA:1.10.10.10 136 215 3.4E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS39450 8c8b6ce066efa5f4703cf4f4a4724d4d 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 198 8.1E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS39450 8c8b6ce066efa5f4703cf4f4a4724d4d 218 Gene3D G3DSA:3.40.50.2300 4 135 7.8E-27 T 28-03-2018 CU254_RS02595 ea28ae8b9cdad07e9b88e006ebdf28e1 296 Gene3D G3DSA:3.40.50.720 1 125 9.9E-40 T 28-03-2018 CU254_RS02595 ea28ae8b9cdad07e9b88e006ebdf28e1 296 SMART SM00881 4 104 5.9E-30 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CU254_RS02595 ea28ae8b9cdad07e9b88e006ebdf28e1 296 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 158 185 - T 28-03-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site CU254_RS02595 ea28ae8b9cdad07e9b88e006ebdf28e1 296 Pfam PF00549 CoA-ligase 158 275 2.3E-13 T 28-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CU254_RS02595 ea28ae8b9cdad07e9b88e006ebdf28e1 296 PRINTS PR01798 Succinyl-CoA synthase signature 86 103 2.2E-34 T 28-03-2018 CU254_RS02595 ea28ae8b9cdad07e9b88e006ebdf28e1 296 PRINTS PR01798 Succinyl-CoA synthase signature 212 225 2.2E-34 T 28-03-2018 CU254_RS02595 ea28ae8b9cdad07e9b88e006ebdf28e1 296 PRINTS PR01798 Succinyl-CoA synthase signature 244 261 2.2E-34 T 28-03-2018 CU254_RS02595 ea28ae8b9cdad07e9b88e006ebdf28e1 296 PRINTS PR01798 Succinyl-CoA synthase signature 181 199 2.2E-34 T 28-03-2018 CU254_RS02595 ea28ae8b9cdad07e9b88e006ebdf28e1 296 Pfam PF02629 CoA binding domain 7 103 1.4E-25 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CU254_RS02595 ea28ae8b9cdad07e9b88e006ebdf28e1 296 SUPERFAMILY SSF51735 1 128 5.43E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS02595 ea28ae8b9cdad07e9b88e006ebdf28e1 296 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 3 290 2.3E-126 T 28-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CU254_RS02595 ea28ae8b9cdad07e9b88e006ebdf28e1 296 Gene3D G3DSA:3.40.50.261 126 295 9.0E-47 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CU254_RS02595 ea28ae8b9cdad07e9b88e006ebdf28e1 296 PIRSF PIRSF001553 1 295 4.0E-115 T 28-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CU254_RS02595 ea28ae8b9cdad07e9b88e006ebdf28e1 296 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 292 38.636 T 28-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CU254_RS02595 ea28ae8b9cdad07e9b88e006ebdf28e1 296 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 240 253 - T 28-03-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site CU254_RS02595 ea28ae8b9cdad07e9b88e006ebdf28e1 296 SUPERFAMILY SSF52210 129 292 5.63E-45 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CU254_RS35620 a2185984178306d4dafedea81bf4b0d3 416 PIRSF PIRSF000521 2 127 4.3E-6 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CU254_RS35620 a2185984178306d4dafedea81bf4b0d3 416 PIRSF PIRSF000521 120 159 0.094 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CU254_RS35620 a2185984178306d4dafedea81bf4b0d3 416 PIRSF PIRSF000521 180 414 8.6E-29 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CU254_RS35620 a2185984178306d4dafedea81bf4b0d3 416 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 232 268 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CU254_RS35620 a2185984178306d4dafedea81bf4b0d3 416 TIGRFAM TIGR00709 dat: 2,4-diaminobutyrate 4-transaminase 2 415 1.6E-147 T 28-03-2018 IPR004637 2,4-diaminobutyrate 4-transaminase GO:0008483|GO:0009058 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761|MetaCyc: PWY-7855 CU254_RS35620 a2185984178306d4dafedea81bf4b0d3 416 SUPERFAMILY SSF53383 9 411 1.89E-105 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS35620 a2185984178306d4dafedea81bf4b0d3 416 Gene3D G3DSA:3.40.640.10 175 302 9.4E-32 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS35620 a2185984178306d4dafedea81bf4b0d3 416 Gene3D G3DSA:3.90.1150.10 303 416 5.2E-20 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS35620 a2185984178306d4dafedea81bf4b0d3 416 TIGRFAM TIGR02407 ectoine_ectB: diaminobutyrate--2-oxoglutarate aminotransferase 3 412 2.0E-198 T 28-03-2018 IPR012773 Ectoine biosynthetic protein GO:0019491|GO:0030170|GO:0047307 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761|MetaCyc: PWY-7855 CU254_RS35620 a2185984178306d4dafedea81bf4b0d3 416 Pfam PF00202 Aminotransferase class-III 19 410 2.6E-75 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CU254_RS35620 a2185984178306d4dafedea81bf4b0d3 416 Gene3D G3DSA:3.90.1150.10 1 163 9.7E-38 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS03600 88328103c683a0af18abbb0b2f5d293f 106 Gene3D G3DSA:3.30.70.20 2 44 2.6E-11 T 28-03-2018 CU254_RS03600 88328103c683a0af18abbb0b2f5d293f 106 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CU254_RS03600 88328103c683a0af18abbb0b2f5d293f 106 PRINTS PR00354 7Fe ferredoxin signature 35 52 2.0E-16 T 28-03-2018 IPR000813 7Fe ferredoxin GO:0009055 CU254_RS03600 88328103c683a0af18abbb0b2f5d293f 106 PRINTS PR00354 7Fe ferredoxin signature 9 19 2.0E-16 T 28-03-2018 IPR000813 7Fe ferredoxin GO:0009055 CU254_RS03600 88328103c683a0af18abbb0b2f5d293f 106 PRINTS PR00354 7Fe ferredoxin signature 19 29 2.0E-16 T 28-03-2018 IPR000813 7Fe ferredoxin GO:0009055 CU254_RS03600 88328103c683a0af18abbb0b2f5d293f 106 Gene3D G3DSA:3.30.70.20 45 99 2.9E-9 T 28-03-2018 CU254_RS03600 88328103c683a0af18abbb0b2f5d293f 106 Pfam PF00037 4Fe-4S binding domain 34 56 1.2E-8 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CU254_RS03600 88328103c683a0af18abbb0b2f5d293f 106 SUPERFAMILY SSF54862 3 85 3.39E-21 T 28-03-2018 CU254_RS24600 bf5edd013ce1e9805318e4ac0689fd39 360 Pfam PF00953 Glycosyl transferase family 4 88 277 5.5E-38 T 28-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CU254_RS24600 bf5edd013ce1e9805318e4ac0689fd39 360 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 3 352 23.273 T 28-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CU254_RS24600 bf5edd013ce1e9805318e4ac0689fd39 360 ProSitePatterns PS01348 MraY family signature 2. 181 192 - T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CU254_RS24600 bf5edd013ce1e9805318e4ac0689fd39 360 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 15 348 5.4E-90 T 28-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CU254_RS24600 bf5edd013ce1e9805318e4ac0689fd39 360 ProSitePatterns PS01347 MraY family signature 1. 46 58 - T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CU254_RS24600 bf5edd013ce1e9805318e4ac0689fd39 360 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 46 58 7.0E-6 T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CU254_RS02845 97c0aec8351e84875e62765598005d58 424 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 335 403 7.9E-21 T 28-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CU254_RS02845 97c0aec8351e84875e62765598005d58 424 SUPERFAMILY SSF52418 74 315 3.01E-81 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CU254_RS02845 97c0aec8351e84875e62765598005d58 424 Pfam PF02885 Glycosyl transferase family, helical bundle domain 6 68 1.4E-18 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CU254_RS02845 97c0aec8351e84875e62765598005d58 424 Pfam PF00591 Glycosyl transferase family, a/b domain 78 287 1.0E-33 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CU254_RS02845 97c0aec8351e84875e62765598005d58 424 Gene3D G3DSA:1.20.970.10 1 69 6.5E-22 T 28-03-2018 CU254_RS02845 97c0aec8351e84875e62765598005d58 424 SMART SM00941 334 408 3.1E-29 T 28-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CU254_RS02845 97c0aec8351e84875e62765598005d58 424 SUPERFAMILY SSF47648 4 71 2.35E-20 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CU254_RS02845 97c0aec8351e84875e62765598005d58 424 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 111 126 - T 28-03-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CU254_RS02845 97c0aec8351e84875e62765598005d58 424 Gene3D G3DSA:3.90.1170.30 324 414 5.1E-27 T 28-03-2018 CU254_RS02845 97c0aec8351e84875e62765598005d58 424 PIRSF PIRSF000478 2 423 1.6E-146 T 28-03-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CU254_RS02845 97c0aec8351e84875e62765598005d58 424 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 6 403 2.0E-160 T 28-03-2018 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 CU254_RS02845 97c0aec8351e84875e62765598005d58 424 SUPERFAMILY SSF54680 322 422 2.75E-24 T 28-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CU254_RS02845 97c0aec8351e84875e62765598005d58 424 Gene3D G3DSA:3.40.1030.10 71 323 7.3E-81 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CU254_RS19940 2ff2a6a787f34da5d65fc15388c48b69 247 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 158 169 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CU254_RS19940 2ff2a6a787f34da5d65fc15388c48b69 247 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 4 119 1.2E-23 T 28-03-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CU254_RS19940 2ff2a6a787f34da5d65fc15388c48b69 247 SUPERFAMILY SSF46548 118 240 2.44E-23 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CU254_RS19940 2ff2a6a787f34da5d65fc15388c48b69 247 Gene3D G3DSA:3.10.20.30 1 115 2.1E-24 T 28-03-2018 IPR012675 Beta-grasp domain CU254_RS19940 2ff2a6a787f34da5d65fc15388c48b69 247 Gene3D G3DSA:1.10.1060.10 119 247 7.9E-18 T 28-03-2018 CU254_RS19940 2ff2a6a787f34da5d65fc15388c48b69 247 Pfam PF12838 4Fe-4S dicluster domain 157 227 2.1E-10 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CU254_RS19940 2ff2a6a787f34da5d65fc15388c48b69 247 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 58 66 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CU254_RS19940 2ff2a6a787f34da5d65fc15388c48b69 247 SUPERFAMILY SSF54292 2 115 2.36E-21 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 3274 3409 8.3E-35 T 28-03-2018 IPR010060 Non-ribosomal peptide synthase CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 1861 2003 1.8E-37 T 28-03-2018 IPR010060 Non-ribosomal peptide synthase CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 4686 4825 1.3E-35 T 28-03-2018 IPR010060 Non-ribosomal peptide synthase CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Gene3D G3DSA:3.30.300.30 2836 2946 6.4E-35 T 28-03-2018 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Gene3D G3DSA:3.30.300.30 402 516 5.2E-38 T 28-03-2018 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Gene3D G3DSA:3.30.300.30 4244 4353 5.9E-39 T 28-03-2018 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Gene3D G3DSA:3.30.300.30 5660 5773 3.7E-41 T 28-03-2018 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Gene3D G3DSA:3.30.300.30 1414 1525 3.1E-36 T 28-03-2018 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 SUPERFAMILY SSF52777 3415 3588 3.0E-42 T 28-03-2018 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 SUPERFAMILY SSF52777 764 1007 1.67E-54 T 28-03-2018 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Gene3D G3DSA:1.10.1200.10 2947 3008 3.4E-23 T 28-03-2018 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2591 2602 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 SUPERFAMILY SSF52777 2009 2200 3.34E-40 T 28-03-2018 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 ProSitePatterns PS00012 Phosphopantetheine attachment site. 5792 5807 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 SUPERFAMILY SSF47336 1515 1586 1.83E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Gene3D G3DSA:3.40.50.980 2447 2592 1.1E-44 T 28-03-2018 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Gene3D G3DSA:3.40.50.980 162 317 4.7E-30 T 28-03-2018 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Gene3D G3DSA:3.40.50.980 5419 5571 2.2E-30 T 28-03-2018 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Gene3D G3DSA:3.40.50.980 4005 4151 3.2E-27 T 28-03-2018 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Gene3D G3DSA:3.40.50.980 1175 1326 3.5E-30 T 28-03-2018 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Gene3D G3DSA:3.40.50.980 2593 2743 4.4E-33 T 28-03-2018 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 SUPERFAMILY SSF52777 3015 3146 6.45E-27 T 28-03-2018 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2965 2980 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Gene3D G3DSA:2.30.38.10 5574 5655 1.9E-27 T 28-03-2018 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Gene3D G3DSA:2.30.38.10 1328 1409 1.2E-24 T 28-03-2018 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Gene3D G3DSA:2.30.38.10 4158 4239 1.9E-23 T 28-03-2018 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Gene3D G3DSA:2.30.38.10 2750 2831 4.0E-25 T 28-03-2018 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Gene3D G3DSA:2.30.38.10 318 397 4.5E-26 T 28-03-2018 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Gene3D G3DSA:3.30.559.10 1590 1677 6.8E-7 T 28-03-2018 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Gene3D G3DSA:3.30.559.10 3009 3097 4.1E-11 T 28-03-2018 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Gene3D G3DSA:3.30.559.10 4423 4580 1.7E-21 T 28-03-2018 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 SUPERFAMILY SSF47336 2934 3003 5.63E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Pfam PF00668 Condensation domain 1600 1666 4.3E-5 T 28-03-2018 IPR001242 Condensation domain CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Pfam PF00668 Condensation domain 1685 1989 4.9E-50 T 28-03-2018 IPR001242 Condensation domain CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Pfam PF00668 Condensation domain 3101 3396 6.0E-48 T 28-03-2018 IPR001242 Condensation domain CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Pfam PF00668 Condensation domain 2010 2435 9.5E-70 T 28-03-2018 IPR001242 Condensation domain CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Pfam PF00668 Condensation domain 594 1018 6.0E-85 T 28-03-2018 IPR001242 Condensation domain CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Pfam PF00668 Condensation domain 4831 5265 2.5E-83 T 28-03-2018 IPR001242 Condensation domain CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Pfam PF00668 Condensation domain 4429 4811 6.2E-51 T 28-03-2018 IPR001242 Condensation domain CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Pfam PF00668 Condensation domain 3020 3081 6.8E-7 T 28-03-2018 IPR001242 Condensation domain CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Pfam PF00668 Condensation domain 3416 3843 9.4E-78 T 28-03-2018 IPR001242 Condensation domain CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Gene3D G3DSA:3.40.50.980 11 161 5.7E-39 T 28-03-2018 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Gene3D G3DSA:3.40.50.980 5275 5418 3.8E-32 T 28-03-2018 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Gene3D G3DSA:3.40.50.980 1026 1174 8.1E-39 T 28-03-2018 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Gene3D G3DSA:3.40.50.980 3857 4004 1.9E-37 T 28-03-2018 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 SMART SM00823 Phosphopantetheine attachment site 511 580 2.4E-9 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 SMART SM00823 Phosphopantetheine attachment site 2938 3009 1.9E-5 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 SMART SM00823 Phosphopantetheine attachment site 1522 1590 1.9E-7 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 SMART SM00823 Phosphopantetheine attachment site 4350 4418 1.4E-7 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 SMART SM00823 Phosphopantetheine attachment site 5768 5837 0.0019 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 SUPERFAMILY SSF47336 5761 5834 2.09E-17 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 ProSitePatterns PS00455 Putative AMP-binding domain signature. 5413 5424 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 SUPERFAMILY SSF52777 4575 4801 7.34E-35 T 28-03-2018 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 SUPERFAMILY SSF56801 3830 4363 6.28E-145 T 28-03-2018 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 SUPERFAMILY SSF52777 5008 5249 3.22E-58 T 28-03-2018 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 ProSitePatterns PS00455 Putative AMP-binding domain signature. 3999 4010 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 ProSitePatterns PS00012 Phosphopantetheine attachment site. 535 550 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 SUPERFAMILY SSF52777 3158 3385 6.11E-38 T 28-03-2018 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 SUPERFAMILY SSF52777 4424 4562 6.34E-28 T 28-03-2018 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Pfam PF00550 Phosphopantetheine attachment site 4352 4413 1.3E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Pfam PF00550 Phosphopantetheine attachment site 1524 1583 2.8E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Pfam PF00550 Phosphopantetheine attachment site 513 576 8.5E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Pfam PF00550 Phosphopantetheine attachment site 2943 3004 1.0E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Pfam PF00550 Phosphopantetheine attachment site 5770 5832 4.1E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 SUPERFAMILY SSF56801 997 1530 6.67E-144 T 28-03-2018 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 SUPERFAMILY SSF52777 1600 1733 1.33E-24 T 28-03-2018 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 SUPERFAMILY SSF47336 505 577 1.31E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1546 1561 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 SMART SM01294 512 576 0.0027 T 28-03-2018 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 SUPERFAMILY SSF52777 2186 2441 1.33E-53 T 28-03-2018 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 SUPERFAMILY SSF52777 4830 5022 1.67E-45 T 28-03-2018 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 SUPERFAMILY SSF47336 4344 4413 1.7E-18 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 SUPERFAMILY SSF52777 590 775 1.67E-43 T 28-03-2018 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Gene3D G3DSA:1.10.1200.10 1526 1589 1.1E-21 T 28-03-2018 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Gene3D G3DSA:1.10.1200.10 4354 4422 5.2E-23 T 28-03-2018 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Gene3D G3DSA:1.10.1200.10 517 592 4.9E-23 T 28-03-2018 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 SUPERFAMILY SSF52777 1744 1979 1.33E-40 T 28-03-2018 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Gene3D G3DSA:3.30.559.10 593 768 6.2E-38 T 28-03-2018 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Gene3D G3DSA:3.30.559.10 1678 1746 1.3E-8 T 28-03-2018 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 SUPERFAMILY SSF56801 2412 2954 2.49E-150 T 28-03-2018 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Pfam PF13193 AMP-binding enzyme C-terminal domain 5673 5744 2.8E-13 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Pfam PF13193 AMP-binding enzyme C-terminal domain 415 488 4.4E-12 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Pfam PF13193 AMP-binding enzyme C-terminal domain 1427 1498 6.1E-10 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Pfam PF13193 AMP-binding enzyme C-terminal domain 2849 2917 1.5E-9 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Pfam PF13193 AMP-binding enzyme C-terminal domain 4257 4325 6.2E-13 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Gene3D G3DSA:1.10.1200.10 5774 5837 1.1E-20 T 28-03-2018 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 5305 5689 2.9E-121 T 28-03-2018 IPR010071 Amino acid adenylation domain CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 3886 4273 1.1E-120 T 28-03-2018 IPR010071 Amino acid adenylation domain CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2475 2865 4.3E-126 T 28-03-2018 IPR010071 Amino acid adenylation domain CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1056 1443 3.3E-123 T 28-03-2018 IPR010071 Amino acid adenylation domain CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 41 431 1.5E-120 T 28-03-2018 IPR010071 Amino acid adenylation domain CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 SUPERFAMILY SSF52777 3595 3853 4.45E-55 T 28-03-2018 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 SUPERFAMILY SSF56801 5250 5780 7.46E-144 T 28-03-2018 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Pfam PF00501 AMP-binding enzyme 2454 2841 8.1E-96 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Pfam PF00501 AMP-binding enzyme 20 407 2.8E-90 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Pfam PF00501 AMP-binding enzyme 1035 1419 4.4E-90 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Pfam PF00501 AMP-binding enzyme 3865 4249 1.5E-84 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Pfam PF00501 AMP-binding enzyme 5284 5665 1.3E-85 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Gene3D G3DSA:3.30.559.10 3373 3614 1.8E-40 T 28-03-2018 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Gene3D G3DSA:3.30.559.10 4745 5025 3.1E-42 T 28-03-2018 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Gene3D G3DSA:3.30.559.10 1963 2203 9.3E-36 T 28-03-2018 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 Gene3D G3DSA:3.30.559.10 3098 3174 1.5E-8 T 28-03-2018 CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4374 4389 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 ProSitePatterns PS00455 Putative AMP-binding domain signature. 156 167 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS16005 a54100f72931f9cc96a74b635d54654d 5850 SUPERFAMILY SSF56801 12 524 4.84E-143 T 28-03-2018 CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 SMART SM00825 Beta-ketoacyl synthase 1003 1428 3.5E-205 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 SMART SM00825 Beta-ketoacyl synthase 16 426 1.2E-155 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 SMART SM00825 Beta-ketoacyl synthase 2219 2645 1.3E-200 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 Gene3D G3DSA:3.40.50.720 3730 3837 3.6E-16 T 28-03-2018 CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 SUPERFAMILY SSF52151 723 815 1.26E-66 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 SUPERFAMILY SSF52151 529 659 1.26E-66 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 SUPERFAMILY SSF51735 1604 1806 7.87E-31 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 SUPERFAMILY SSF51735 3911 4151 3.87E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 Gene3D G3DSA:3.30.70.250 669 712 7.4E-18 T 28-03-2018 CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 Gene3D G3DSA:3.30.70.250 2884 2932 3.1E-9 T 28-03-2018 CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 Gene3D G3DSA:3.40.366.10 526 668 4.5E-43 T 28-03-2018 CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 SUPERFAMILY SSF47336 906 1016 7.85E-21 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 Gene3D G3DSA:3.40.47.10 7 261 6.3E-73 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 Gene3D G3DSA:3.40.47.10 994 1262 8.4E-81 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 Gene3D G3DSA:3.40.47.10 2216 2478 1.1E-82 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 SUPERFAMILY SSF52151 2941 3034 6.28E-53 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 SUPERFAMILY SSF52151 2749 2877 6.28E-53 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 Pfam PF14765 Polyketide synthase dehydratase 3119 3382 1.4E-49 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 Gene3D G3DSA:3.40.47.10 2481 2642 3.2E-59 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 Gene3D G3DSA:3.40.47.10 264 424 2.1E-53 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 Gene3D G3DSA:1.10.1200.10 892 986 4.4E-17 T 28-03-2018 CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 Gene3D G3DSA:1.10.1200.10 4197 4296 2.2E-18 T 28-03-2018 CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 Gene3D G3DSA:1.10.1200.10 2083 2215 1.4E-15 T 28-03-2018 CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 Pfam PF13602 Zinc-binding dehydrogenase 3774 3905 1.3E-13 T 28-03-2018 CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 15 246 1.2E-70 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2217 2466 2.5E-86 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1001 1250 6.4E-82 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 Gene3D G3DSA:3.40.366.10 713 843 7.3E-32 T 28-03-2018 CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 Gene3D G3DSA:3.40.366.10 2933 3056 3.6E-20 T 28-03-2018 CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3915 4095 7.7E-50 T 28-03-2018 CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1819 1998 4.5E-43 T 28-03-2018 CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1258 1375 4.1E-41 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 257 373 9.7E-37 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2474 2591 9.6E-45 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 Pfam PF08659 KR domain 3915 4093 1.9E-52 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 Pfam PF08659 KR domain 1819 1996 5.6E-54 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 533 828 1.7E-98 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2752 3049 2.8E-55 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1378 1492 1.2E-13 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2594 2715 7.9E-17 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 379 496 3.7E-17 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 SUPERFAMILY SSF53901 999 1365 7.88E-99 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 SMART SM00826 3119 3278 3.0E-56 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 Gene3D G3DSA:3.40.47.10 1266 1430 1.5E-57 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 SUPERFAMILY SSF47336 4184 4272 4.71E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 Gene3D G3DSA:3.90.180.10 3593 3729 1.3E-32 T 28-03-2018 CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 SUPERFAMILY SSF55048 658 722 6.8E-12 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 SUPERFAMILY SSF51735 3389 3581 5.12E-25 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 Pfam PF00698 Acyl transferase domain 533 846 1.9E-51 T 28-03-2018 IPR014043 Acyl transferase CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 Pfam PF00698 Acyl transferase domain 2750 3038 4.8E-56 T 28-03-2018 IPR014043 Acyl transferase CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 Gene3D G3DSA:3.40.366.10 2748 2883 2.4E-34 T 28-03-2018 CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 SUPERFAMILY SSF53901 399 422 1.77E-74 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 SUPERFAMILY SSF53901 15 369 1.77E-74 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 SMART SM00823 Phosphopantetheine attachment site 2090 2162 7.0E-18 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 SMART SM00823 Phosphopantetheine attachment site 4188 4260 6.1E-26 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 SMART SM00823 Phosphopantetheine attachment site 911 983 9.2E-20 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 SMART SM00829 3601 3905 4.7E-135 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1163 1179 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 Pfam PF00550 Phosphopantetheine attachment site 914 979 5.9E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 Pfam PF00550 Phosphopantetheine attachment site 4196 4256 1.4E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 Pfam PF00550 Phosphopantetheine attachment site 2092 2158 2.4E-8 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 SUPERFAMILY SSF51735 3699 3876 2.67E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 SUPERFAMILY SSF47336 2084 2163 1.18E-17 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 SUPERFAMILY SSF47336 2201 2230 1.18E-17 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 SUPERFAMILY SSF53901 2214 2587 2.13E-101 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 Gene3D G3DSA:3.10.129.10 3121 3246 1.1E-10 T 28-03-2018 CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 Gene3D G3DSA:3.90.180.10 3838 3909 0.13 T 28-03-2018 CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 SUPERFAMILY SSF51735 1813 2036 7.01E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 SUPERFAMILY SSF55048 2875 2936 1.7E-6 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 SUPERFAMILY SSF50129 3614 3732 5.37E-23 T 28-03-2018 IPR011032 GroES-like CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 Gene3D G3DSA:3.40.50.720 1812 2054 8.0E-49 T 28-03-2018 CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 Gene3D G3DSA:3.40.50.720 3911 4196 2.7E-42 T 28-03-2018 CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2379 2395 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 SMART SM01294 912 979 9.9E-5 T 28-03-2018 CU254_RS19370 3297bb7e093df4ed83cc81f04a5cd412 4314 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 3619 3674 1.3E-4 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CU254_RS38175 3ced136897042748378e7e230b5f77b7 340 SMART SM00354 8 78 4.2E-19 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CU254_RS38175 3ced136897042748378e7e230b5f77b7 340 Gene3D G3DSA:3.40.50.2300 182 313 1.2E-41 T 28-03-2018 CU254_RS38175 3ced136897042748378e7e230b5f77b7 340 Pfam PF13377 Periplasmic binding protein-like domain 176 336 1.2E-38 T 28-03-2018 CU254_RS38175 3ced136897042748378e7e230b5f77b7 340 Gene3D G3DSA:3.40.50.2300 63 181 2.6E-34 T 28-03-2018 CU254_RS38175 3ced136897042748378e7e230b5f77b7 340 SUPERFAMILY SSF47413 8 66 2.09E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS38175 3ced136897042748378e7e230b5f77b7 340 Gene3D G3DSA:1.10.10.10 2 24 0.0022 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS38175 3ced136897042748378e7e230b5f77b7 340 Gene3D G3DSA:1.10.260.40 25 62 5.5E-19 T 28-03-2018 CU254_RS38175 3ced136897042748378e7e230b5f77b7 340 Pfam PF00356 Bacterial regulatory proteins, lacI family 12 53 1.6E-13 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CU254_RS38175 3ced136897042748378e7e230b5f77b7 340 SUPERFAMILY SSF53822 67 337 1.63E-72 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CU254_RS03465 46c5dbc71d2a584dd27c10299832ede0 634 SUPERFAMILY SSF54980 537 617 1.15E-9 T 28-03-2018 IPR035647 EF-G domain III/V-like CU254_RS03465 46c5dbc71d2a584dd27c10299832ede0 634 Gene3D G3DSA:3.30.70.240 545 618 5.1E-8 T 28-03-2018 CU254_RS03465 46c5dbc71d2a584dd27c10299832ede0 634 Pfam PF03764 Elongation factor G, domain IV 444 533 2.0E-16 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CU254_RS03465 46c5dbc71d2a584dd27c10299832ede0 634 SUPERFAMILY SSF54980 345 416 4.32E-10 T 28-03-2018 IPR035647 EF-G domain III/V-like CU254_RS03465 46c5dbc71d2a584dd27c10299832ede0 634 SMART SM00889 431 534 5.6E-10 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CU254_RS03465 46c5dbc71d2a584dd27c10299832ede0 634 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 44 59 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site CU254_RS03465 46c5dbc71d2a584dd27c10299832ede0 634 SUPERFAMILY SSF52540 4 241 1.15E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS03465 46c5dbc71d2a584dd27c10299832ede0 634 SUPERFAMILY SSF54211 443 534 4.93E-15 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CU254_RS03465 46c5dbc71d2a584dd27c10299832ede0 634 Gene3D G3DSA:2.40.30.10 247 344 1.9E-14 T 28-03-2018 CU254_RS03465 46c5dbc71d2a584dd27c10299832ede0 634 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 1 147 1.5E-24 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CU254_RS03465 46c5dbc71d2a584dd27c10299832ede0 634 Pfam PF00009 Elongation factor Tu GTP binding domain 3 241 2.7E-53 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CU254_RS03465 46c5dbc71d2a584dd27c10299832ede0 634 SUPERFAMILY SSF50447 224 335 1.41E-14 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CU254_RS03465 46c5dbc71d2a584dd27c10299832ede0 634 Pfam PF00679 Elongation factor G C-terminus 537 615 1.0E-10 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CU254_RS03465 46c5dbc71d2a584dd27c10299832ede0 634 PRINTS PR00315 GTP-binding elongation factor signature 87 98 7.6E-15 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CU254_RS03465 46c5dbc71d2a584dd27c10299832ede0 634 PRINTS PR00315 GTP-binding elongation factor signature 5 18 7.6E-15 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CU254_RS03465 46c5dbc71d2a584dd27c10299832ede0 634 PRINTS PR00315 GTP-binding elongation factor signature 123 132 7.6E-15 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CU254_RS03465 46c5dbc71d2a584dd27c10299832ede0 634 PRINTS PR00315 GTP-binding elongation factor signature 51 59 7.6E-15 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CU254_RS03465 46c5dbc71d2a584dd27c10299832ede0 634 PRINTS PR00315 GTP-binding elongation factor signature 71 81 7.6E-15 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CU254_RS03465 46c5dbc71d2a584dd27c10299832ede0 634 Gene3D G3DSA:3.40.50.300 1 245 3.8E-39 T 28-03-2018 CU254_RS03465 46c5dbc71d2a584dd27c10299832ede0 634 Gene3D G3DSA:3.30.230.10 436 544 1.0E-17 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CU254_RS03465 46c5dbc71d2a584dd27c10299832ede0 634 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 506 523 9.7E-23 T 28-03-2018 CU254_RS03465 46c5dbc71d2a584dd27c10299832ede0 634 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 109 132 9.7E-23 T 28-03-2018 CU254_RS03465 46c5dbc71d2a584dd27c10299832ede0 634 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 214 236 9.7E-23 T 28-03-2018 CU254_RS03465 46c5dbc71d2a584dd27c10299832ede0 634 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 268 294 9.7E-23 T 28-03-2018 CU254_RS03465 46c5dbc71d2a584dd27c10299832ede0 634 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 457 471 9.7E-23 T 28-03-2018 CU254_RS03465 46c5dbc71d2a584dd27c10299832ede0 634 PRINTS PR01037 Tetracycline resistance protein TetO/TetQ/TetM family signature 472 494 9.7E-23 T 28-03-2018 CU254_RS03465 46c5dbc71d2a584dd27c10299832ede0 634 Gene3D G3DSA:3.30.70.870 345 415 7.1E-10 T 28-03-2018 CU254_RS04500 233676c1bb69c582b5768adfa47df98f 137 Gene3D G3DSA:3.40.250.10 10 129 1.9E-21 T 28-03-2018 IPR001763 Rhodanese-like domain CU254_RS04500 233676c1bb69c582b5768adfa47df98f 137 SUPERFAMILY SSF52821 25 135 2.75E-25 T 28-03-2018 IPR001763 Rhodanese-like domain CU254_RS04500 233676c1bb69c582b5768adfa47df98f 137 ProSitePatterns PS00380 Rhodanese signature 1. 54 65 - T 28-03-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 CU254_RS04500 233676c1bb69c582b5768adfa47df98f 137 SMART SM00450 29 126 5.4E-13 T 28-03-2018 IPR001763 Rhodanese-like domain CU254_RS04500 233676c1bb69c582b5768adfa47df98f 137 Pfam PF00581 Rhodanese-like domain 30 122 6.0E-12 T 28-03-2018 IPR001763 Rhodanese-like domain CU254_RS06665 669c00068d4d7366f9bfe202b092e10f 125 Pfam PF00893 Small Multidrug Resistance protein 13 104 5.6E-19 T 28-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 CU254_RS06665 669c00068d4d7366f9bfe202b092e10f 125 SUPERFAMILY SSF103481 17 116 6.54E-18 T 28-03-2018 CU254_RS29810 9d650e16eb27ead9be25fce7a5b9c2f9 538 ProSitePatterns PS00211 ABC transporters family signature. 459 473 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS29810 9d650e16eb27ead9be25fce7a5b9c2f9 538 Pfam PF00005 ABC transporter 364 487 4.2E-17 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS29810 9d650e16eb27ead9be25fce7a5b9c2f9 538 Pfam PF00005 ABC transporter 19 187 2.9E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS29810 9d650e16eb27ead9be25fce7a5b9c2f9 538 SUPERFAMILY SSF52540 13 230 2.57E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS29810 9d650e16eb27ead9be25fce7a5b9c2f9 538 SUPERFAMILY SSF52540 364 528 3.98E-27 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS29810 9d650e16eb27ead9be25fce7a5b9c2f9 538 Gene3D G3DSA:3.40.50.300 2 270 1.7E-49 T 28-03-2018 CU254_RS29810 9d650e16eb27ead9be25fce7a5b9c2f9 538 Gene3D G3DSA:3.40.50.300 343 535 1.5E-29 T 28-03-2018 CU254_RS29810 9d650e16eb27ead9be25fce7a5b9c2f9 538 SMART SM00382 369 532 1.1E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS29810 9d650e16eb27ead9be25fce7a5b9c2f9 538 SMART SM00382 28 231 8.4E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS11040 55110b335a5baf52e0bf5a5b50ccbd6a 310 PIRSF PIRSF000105 1 301 8.2E-80 T 28-03-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 CU254_RS11040 55110b335a5baf52e0bf5a5b50ccbd6a 310 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 1 168 7.5E-43 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CU254_RS11040 55110b335a5baf52e0bf5a5b50ccbd6a 310 SUPERFAMILY SSF48179 173 271 2.13E-20 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CU254_RS11040 55110b335a5baf52e0bf5a5b50ccbd6a 310 Gene3D G3DSA:1.10.1040.10 172 276 1.3E-20 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CU254_RS11040 55110b335a5baf52e0bf5a5b50ccbd6a 310 SUPERFAMILY SSF51735 1 170 1.97E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS11040 55110b335a5baf52e0bf5a5b50ccbd6a 310 Gene3D G3DSA:3.40.50.720 1 171 2.5E-36 T 28-03-2018 CU254_RS11040 55110b335a5baf52e0bf5a5b50ccbd6a 310 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 173 270 9.9E-16 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CU254_RS18260 43d09eb9d6b6154999e6b532e8e45434 498 SMART SM00014 67 176 8.0E-27 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CU254_RS18260 43d09eb9d6b6154999e6b532e8e45434 498 SUPERFAMILY SSF111331 203 495 4.14E-48 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain CU254_RS18260 43d09eb9d6b6154999e6b532e8e45434 498 Pfam PF00781 Diacylglycerol kinase catalytic domain 204 308 3.5E-15 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CU254_RS18260 43d09eb9d6b6154999e6b532e8e45434 498 Pfam PF01569 PAP2 superfamily 70 180 1.1E-17 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CU254_RS18260 43d09eb9d6b6154999e6b532e8e45434 498 SMART SM00046 203 333 2.2E-4 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CU254_RS18260 43d09eb9d6b6154999e6b532e8e45434 498 Gene3D G3DSA:1.20.144.10 11 198 3.7E-30 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CU254_RS18260 43d09eb9d6b6154999e6b532e8e45434 498 SUPERFAMILY SSF48317 21 179 3.66E-34 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CU254_RS18260 43d09eb9d6b6154999e6b532e8e45434 498 Gene3D G3DSA:3.40.50.10330 199 333 6.9E-16 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 CU254_RS09610 03844197b079f5f6df23c3fbec19cfb3 525 Gene3D G3DSA:3.40.50.300 266 453 6.0E-4 T 28-03-2018 CU254_RS09610 03844197b079f5f6df23c3fbec19cfb3 525 Pfam PF01580 FtsK/SpoIIIE family 256 458 1.2E-10 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CU254_RS09610 03844197b079f5f6df23c3fbec19cfb3 525 SUPERFAMILY SSF52540 245 499 6.3E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS00880 ce40619ec74c8a7963fc21beb3ecdd30 213 Gene3D G3DSA:2.20.25.10 9 41 1.4E-5 T 28-03-2018 CU254_RS00880 ce40619ec74c8a7963fc21beb3ecdd30 213 SUPERFAMILY SSF52540 46 205 3.07E-15 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS00880 ce40619ec74c8a7963fc21beb3ecdd30 213 Gene3D G3DSA:3.40.50.300 44 208 1.1E-14 T 28-03-2018 CU254_RS05395 09b833f0d3d4d0c253a9cf525c164b17 118 SUPERFAMILY SSF52833 1 117 1.87E-27 T 28-03-2018 IPR012336 Thioredoxin-like fold CU254_RS05395 09b833f0d3d4d0c253a9cf525c164b17 118 Pfam PF00462 Glutaredoxin 1 44 6.9E-5 T 28-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 CU254_RS05395 09b833f0d3d4d0c253a9cf525c164b17 118 Pfam PF03960 ArsC family 77 114 5.9E-8 T 28-03-2018 IPR006660 Arsenate reductase-like CU254_RS05395 09b833f0d3d4d0c253a9cf525c164b17 118 Gene3D G3DSA:3.40.30.10 1 117 3.4E-31 T 28-03-2018 CU254_RS19205 8304b132e1c025bec3a2940980d803eb 295 SUPERFAMILY SSF53474 9 290 1.57E-66 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS19205 8304b132e1c025bec3a2940980d803eb 295 PRINTS PR00412 Epoxide hydrolase signature 99 112 1.9E-9 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS19205 8304b132e1c025bec3a2940980d803eb 295 PRINTS PR00412 Epoxide hydrolase signature 36 54 1.9E-9 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS19205 8304b132e1c025bec3a2940980d803eb 295 PRINTS PR00412 Epoxide hydrolase signature 265 287 1.9E-9 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS19205 8304b132e1c025bec3a2940980d803eb 295 Gene3D G3DSA:3.40.50.1820 3 294 3.8E-49 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS19205 8304b132e1c025bec3a2940980d803eb 295 Pfam PF00561 alpha/beta hydrolase fold 30 128 2.5E-20 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS39735 24832f384fe77760bdc40834f9001867 296 Pfam PF01636 Phosphotransferase enzyme family 37 238 3.5E-18 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CU254_RS39735 24832f384fe77760bdc40834f9001867 296 SUPERFAMILY SSF56112 13 264 4.55E-36 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS39735 24832f384fe77760bdc40834f9001867 296 Gene3D G3DSA:3.90.1200.10 108 256 3.4E-22 T 28-03-2018 CU254_RS01135 c544b16f5b5c2677348db44ce602b29c 518 SUPERFAMILY SSF81296 408 515 3.99E-24 T 28-03-2018 IPR014756 Immunoglobulin E-set CU254_RS01135 c544b16f5b5c2677348db44ce602b29c 518 Gene3D G3DSA:3.90.420.10 192 411 1.0E-50 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CU254_RS01135 c544b16f5b5c2677348db44ce602b29c 518 Gene3D G3DSA:2.60.40.650 412 518 2.3E-25 T 28-03-2018 CU254_RS01135 c544b16f5b5c2677348db44ce602b29c 518 Pfam PF00174 Oxidoreductase molybdopterin binding domain 244 396 1.2E-35 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CU254_RS01135 c544b16f5b5c2677348db44ce602b29c 518 SUPERFAMILY SSF56524 226 415 9.16E-56 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CU254_RS39960 16299f94b0d6bebfeca88180f311c9fc 449 Pfam PF07690 Major Facilitator Superfamily 22 404 8.1E-57 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS39960 16299f94b0d6bebfeca88180f311c9fc 449 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 20 412 9.9E-89 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CU254_RS39960 16299f94b0d6bebfeca88180f311c9fc 449 SUPERFAMILY SSF103473 243 448 8.89E-68 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS39960 16299f94b0d6bebfeca88180f311c9fc 449 SUPERFAMILY SSF103473 9 197 8.89E-68 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS39960 16299f94b0d6bebfeca88180f311c9fc 449 Gene3D G3DSA:1.20.1250.20 17 201 5.9E-29 T 28-03-2018 CU254_RS39960 16299f94b0d6bebfeca88180f311c9fc 449 Gene3D G3DSA:1.20.1250.20 254 449 9.0E-31 T 28-03-2018 CU254_RS25070 e101fef7666bdcab01304bed34ddc2fa 236 Pfam PF01144 Coenzyme A transferase 7 215 9.0E-62 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CU254_RS25070 e101fef7666bdcab01304bed34ddc2fa 236 SUPERFAMILY SSF100950 4 224 7.67E-73 T 28-03-2018 CU254_RS25070 e101fef7666bdcab01304bed34ddc2fa 236 SMART SM00882 5 216 9.5E-73 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CU254_RS25070 e101fef7666bdcab01304bed34ddc2fa 236 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 5 216 6.8E-70 T 28-03-2018 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Reactome: R-HSA-77108 CU254_RS25070 e101fef7666bdcab01304bed34ddc2fa 236 Gene3D G3DSA:3.40.1080.10 2 235 3.4E-80 T 28-03-2018 CU254_RS25070 e101fef7666bdcab01304bed34ddc2fa 236 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 18 33 - T 28-03-2018 IPR004163 Coenzyme A transferase binding site GO:0008152|GO:0008410 Reactome: R-HSA-77108 CU254_RS20730 12a21e92009e8a0a8042aea71fd9fd1a 1905 SMART SM01294 1536 1609 7.0E-4 T 28-03-2018 CU254_RS20730 12a21e92009e8a0a8042aea71fd9fd1a 1905 SUPERFAMILY SSF51735 1157 1287 4.53E-15 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS20730 12a21e92009e8a0a8042aea71fd9fd1a 1905 SMART SM00825 Beta-ketoacyl synthase 39 451 2.1E-192 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CU254_RS20730 12a21e92009e8a0a8042aea71fd9fd1a 1905 Pfam PF08659 KR domain 1299 1467 2.3E-53 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS20730 12a21e92009e8a0a8042aea71fd9fd1a 1905 SUPERFAMILY SSF53474 1571 1609 9.57E-33 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS20730 12a21e92009e8a0a8042aea71fd9fd1a 1905 SUPERFAMILY SSF53474 1656 1888 9.57E-33 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS20730 12a21e92009e8a0a8042aea71fd9fd1a 1905 SUPERFAMILY SSF53901 35 395 5.11E-94 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS20730 12a21e92009e8a0a8042aea71fd9fd1a 1905 Gene3D G3DSA:3.40.50.1820 1636 1893 1.2E-16 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS20730 12a21e92009e8a0a8042aea71fd9fd1a 1905 Gene3D G3DSA:3.40.50.720 1298 1549 2.8E-44 T 28-03-2018 CU254_RS20730 12a21e92009e8a0a8042aea71fd9fd1a 1905 SUPERFAMILY SSF47336 1536 1643 2.16E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS20730 12a21e92009e8a0a8042aea71fd9fd1a 1905 Gene3D G3DSA:3.40.47.10 288 449 2.5E-58 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS20730 12a21e92009e8a0a8042aea71fd9fd1a 1905 SUPERFAMILY SSF52151 720 807 1.52E-56 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CU254_RS20730 12a21e92009e8a0a8042aea71fd9fd1a 1905 SUPERFAMILY SSF52151 540 663 1.52E-56 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CU254_RS20730 12a21e92009e8a0a8042aea71fd9fd1a 1905 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 401 515 2.1E-17 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS20730 12a21e92009e8a0a8042aea71fd9fd1a 1905 Pfam PF00975 Thioesterase domain 1686 1884 1.0E-16 T 28-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CU254_RS20730 12a21e92009e8a0a8042aea71fd9fd1a 1905 SMART SM00824 Thioesterase 1681 1887 1.6E-75 T 28-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 CU254_RS20730 12a21e92009e8a0a8042aea71fd9fd1a 1905 Gene3D G3DSA:3.30.70.250 669 703 3.6E-11 T 28-03-2018 CU254_RS20730 12a21e92009e8a0a8042aea71fd9fd1a 1905 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1298 1469 3.2E-47 T 28-03-2018 CU254_RS20730 12a21e92009e8a0a8042aea71fd9fd1a 1905 Pfam PF00550 Phosphopantetheine attachment site 1549 1609 1.1E-8 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS20730 12a21e92009e8a0a8042aea71fd9fd1a 1905 SUPERFAMILY SSF51735 1300 1479 2.94E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS20730 12a21e92009e8a0a8042aea71fd9fd1a 1905 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 281 398 1.2E-40 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CU254_RS20730 12a21e92009e8a0a8042aea71fd9fd1a 1905 Pfam PF00698 Acyl transferase domain 542 797 1.7E-41 T 28-03-2018 IPR014043 Acyl transferase CU254_RS20730 12a21e92009e8a0a8042aea71fd9fd1a 1905 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1568 1583 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CU254_RS20730 12a21e92009e8a0a8042aea71fd9fd1a 1905 Gene3D G3DSA:3.40.366.10 539 668 8.7E-34 T 28-03-2018 CU254_RS20730 12a21e92009e8a0a8042aea71fd9fd1a 1905 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 186 202 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CU254_RS20730 12a21e92009e8a0a8042aea71fd9fd1a 1905 Gene3D G3DSA:3.10.129.10 896 1000 3.0E-6 T 28-03-2018 CU254_RS20730 12a21e92009e8a0a8042aea71fd9fd1a 1905 Gene3D G3DSA:3.40.47.10 30 278 1.4E-72 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS20730 12a21e92009e8a0a8042aea71fd9fd1a 1905 SUPERFAMILY SSF55048 661 717 1.83E-8 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CU254_RS20730 12a21e92009e8a0a8042aea71fd9fd1a 1905 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 543 819 1.8E-81 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CU254_RS20730 12a21e92009e8a0a8042aea71fd9fd1a 1905 SMART SM00826 886 1043 1.4E-74 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS20730 12a21e92009e8a0a8042aea71fd9fd1a 1905 Pfam PF14765 Polyketide synthase dehydratase 886 1149 5.6E-52 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS20730 12a21e92009e8a0a8042aea71fd9fd1a 1905 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 37 273 2.4E-78 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CU254_RS20730 12a21e92009e8a0a8042aea71fd9fd1a 1905 Gene3D G3DSA:3.40.366.10 704 828 7.1E-25 T 28-03-2018 CU254_RS20730 12a21e92009e8a0a8042aea71fd9fd1a 1905 SMART SM00823 Phosphopantetheine attachment site 1543 1613 1.4E-21 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS20730 12a21e92009e8a0a8042aea71fd9fd1a 1905 Gene3D G3DSA:1.10.1200.10 1550 1635 1.2E-18 T 28-03-2018 CU254_RS26005 cd7abc608f46d1c3bbe5a0c1ea86a04f 1080 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 320 4.3E-58 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CU254_RS26005 cd7abc608f46d1c3bbe5a0c1ea86a04f 1080 Gene3D G3DSA:3.90.226.10 564 825 2.0E-47 T 28-03-2018 CU254_RS26005 cd7abc608f46d1c3bbe5a0c1ea86a04f 1080 Gene3D G3DSA:3.90.226.10 826 1068 6.6E-43 T 28-03-2018 CU254_RS26005 cd7abc608f46d1c3bbe5a0c1ea86a04f 1080 SUPERFAMILY SSF51246 330 450 2.83E-29 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CU254_RS26005 cd7abc608f46d1c3bbe5a0c1ea86a04f 1080 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 284 291 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CU254_RS26005 cd7abc608f46d1c3bbe5a0c1ea86a04f 1080 Gene3D G3DSA:2.40.50.100 476 545 4.3E-14 T 28-03-2018 CU254_RS26005 cd7abc608f46d1c3bbe5a0c1ea86a04f 1080 SUPERFAMILY SSF52440 6 113 1.44E-38 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CU254_RS26005 cd7abc608f46d1c3bbe5a0c1ea86a04f 1080 Pfam PF00289 Biotin carboxylase, N-terminal domain 6 111 6.1E-39 T 28-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CU254_RS26005 cd7abc608f46d1c3bbe5a0c1ea86a04f 1080 SUPERFAMILY SSF52096 796 1070 4.62E-50 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS26005 cd7abc608f46d1c3bbe5a0c1ea86a04f 1080 Pfam PF01039 Carboxyl transferase domain 592 1054 2.6E-64 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 CU254_RS26005 cd7abc608f46d1c3bbe5a0c1ea86a04f 1080 Pfam PF02785 Biotin carboxylase C-terminal domain 336 444 1.8E-27 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CU254_RS26005 cd7abc608f46d1c3bbe5a0c1ea86a04f 1080 SUPERFAMILY SSF51230 473 544 4.58E-15 T 28-03-2018 IPR011053 Single hybrid motif CU254_RS26005 cd7abc608f46d1c3bbe5a0c1ea86a04f 1080 SMART SM00878 336 444 1.0E-33 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CU254_RS26005 cd7abc608f46d1c3bbe5a0c1ea86a04f 1080 SUPERFAMILY SSF56059 84 324 6.54E-58 T 28-03-2018 CU254_RS26005 cd7abc608f46d1c3bbe5a0c1ea86a04f 1080 Gene3D G3DSA:3.30.470.20 203 447 2.3E-80 T 28-03-2018 CU254_RS26005 cd7abc608f46d1c3bbe5a0c1ea86a04f 1080 Gene3D G3DSA:3.30.1490.20 132 202 6.2E-14 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CU254_RS26005 cd7abc608f46d1c3bbe5a0c1ea86a04f 1080 Gene3D G3DSA:3.40.50.20 4 131 1.8E-43 T 28-03-2018 CU254_RS26005 cd7abc608f46d1c3bbe5a0c1ea86a04f 1080 Pfam PF00364 Biotin-requiring enzyme 481 544 2.7E-10 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CU254_RS26005 cd7abc608f46d1c3bbe5a0c1ea86a04f 1080 SUPERFAMILY SSF52096 569 820 1.49E-44 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS30140 a6de6b5a1b93f5dc79af638187ea2b85 1775 SUPERFAMILY SSF51735 1174 1351 9.52E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS30140 a6de6b5a1b93f5dc79af638187ea2b85 1775 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 530 833 3.9E-107 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CU254_RS30140 a6de6b5a1b93f5dc79af638187ea2b85 1775 Gene3D G3DSA:3.30.70.250 660 698 1.7E-14 T 28-03-2018 CU254_RS30140 a6de6b5a1b93f5dc79af638187ea2b85 1775 Pfam PF00550 Phosphopantetheine attachment site 1643 1708 2.6E-8 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS30140 a6de6b5a1b93f5dc79af638187ea2b85 1775 Pfam PF08659 KR domain 1364 1543 6.5E-60 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS30140 a6de6b5a1b93f5dc79af638187ea2b85 1775 Gene3D G3DSA:3.10.129.10 900 1026 1.2E-9 T 28-03-2018 CU254_RS30140 a6de6b5a1b93f5dc79af638187ea2b85 1775 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 264 381 7.2E-41 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CU254_RS30140 a6de6b5a1b93f5dc79af638187ea2b85 1775 Gene3D G3DSA:3.40.366.10 699 802 3.5E-27 T 28-03-2018 CU254_RS30140 a6de6b5a1b93f5dc79af638187ea2b85 1775 SUPERFAMILY SSF52151 527 644 6.02E-72 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CU254_RS30140 a6de6b5a1b93f5dc79af638187ea2b85 1775 SUPERFAMILY SSF52151 699 799 6.02E-72 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CU254_RS30140 a6de6b5a1b93f5dc79af638187ea2b85 1775 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1667 1682 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CU254_RS30140 a6de6b5a1b93f5dc79af638187ea2b85 1775 SMART SM00826 900 1059 9.5E-81 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS30140 a6de6b5a1b93f5dc79af638187ea2b85 1775 Pfam PF00698 Acyl transferase domain 529 850 6.2E-56 T 28-03-2018 IPR014043 Acyl transferase CU254_RS30140 a6de6b5a1b93f5dc79af638187ea2b85 1775 SUPERFAMILY SSF47336 1633 1711 2.22E-17 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS30140 a6de6b5a1b93f5dc79af638187ea2b85 1775 SUPERFAMILY SSF53901 15 378 4.62E-100 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS30140 a6de6b5a1b93f5dc79af638187ea2b85 1775 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 169 185 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CU254_RS30140 a6de6b5a1b93f5dc79af638187ea2b85 1775 SUPERFAMILY SSF51735 1362 1621 7.25E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS30140 a6de6b5a1b93f5dc79af638187ea2b85 1775 SMART SM00825 Beta-ketoacyl synthase 22 434 4.6E-206 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CU254_RS30140 a6de6b5a1b93f5dc79af638187ea2b85 1775 Gene3D G3DSA:3.40.366.10 526 659 7.7E-43 T 28-03-2018 CU254_RS30140 a6de6b5a1b93f5dc79af638187ea2b85 1775 Gene3D G3DSA:3.40.47.10 10 261 3.7E-79 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS30140 a6de6b5a1b93f5dc79af638187ea2b85 1775 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1364 1544 3.5E-59 T 28-03-2018 CU254_RS30140 a6de6b5a1b93f5dc79af638187ea2b85 1775 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 20 256 4.0E-82 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CU254_RS30140 a6de6b5a1b93f5dc79af638187ea2b85 1775 SMART SM00823 Phosphopantetheine attachment site 1640 1712 1.6E-23 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS30140 a6de6b5a1b93f5dc79af638187ea2b85 1775 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 384 471 1.4E-12 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS30140 a6de6b5a1b93f5dc79af638187ea2b85 1775 Gene3D G3DSA:3.40.47.10 271 432 1.2E-59 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS30140 a6de6b5a1b93f5dc79af638187ea2b85 1775 Gene3D G3DSA:3.40.50.720 1356 1607 1.1E-48 T 28-03-2018 CU254_RS30140 a6de6b5a1b93f5dc79af638187ea2b85 1775 Gene3D G3DSA:1.10.1200.10 1626 1719 2.2E-15 T 28-03-2018 CU254_RS30140 a6de6b5a1b93f5dc79af638187ea2b85 1775 SUPERFAMILY SSF55048 649 705 1.05E-8 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CU254_RS30140 a6de6b5a1b93f5dc79af638187ea2b85 1775 SMART SM01294 1641 1708 1.6E-4 T 28-03-2018 CU254_RS30140 a6de6b5a1b93f5dc79af638187ea2b85 1775 Pfam PF14765 Polyketide synthase dehydratase 900 1167 3.2E-56 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS26235 0a15b5f52bd26f1e131c90fd10e5b4dc 1069 Pfam PF11867 Domain of unknown function (DUF3387) 714 1055 8.2E-100 T 28-03-2018 IPR021810 Protein of unknown function DUF3387 CU254_RS26235 0a15b5f52bd26f1e131c90fd10e5b4dc 1069 SUPERFAMILY SSF52540 241 487 1.41E-25 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS26235 0a15b5f52bd26f1e131c90fd10e5b4dc 1069 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 31 712 1.7E-137 T 28-03-2018 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 CU254_RS26235 0a15b5f52bd26f1e131c90fd10e5b4dc 1069 SMART SM00487 273 485 1.3E-15 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CU254_RS26235 0a15b5f52bd26f1e131c90fd10e5b4dc 1069 Gene3D G3DSA:3.40.50.300 525 965 0.15 T 28-03-2018 CU254_RS26235 0a15b5f52bd26f1e131c90fd10e5b4dc 1069 Pfam PF04851 Type III restriction enzyme, res subunit 287 452 7.3E-17 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CU254_RS26235 0a15b5f52bd26f1e131c90fd10e5b4dc 1069 Gene3D G3DSA:3.40.50.300 32 474 3.4E-27 T 28-03-2018 CU254_RS26235 0a15b5f52bd26f1e131c90fd10e5b4dc 1069 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 7 213 6.1E-20 T 28-03-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 CU254_RS12285 a313d1143d0dad7e27ac3ea7f3a5b3cb 367 SUPERFAMILY SSF54001 247 346 2.06E-7 T 28-03-2018 CU254_RS12285 a313d1143d0dad7e27ac3ea7f3a5b3cb 367 Pfam PF05257 CHAP domain 254 341 3.7E-11 T 28-03-2018 IPR007921 CHAP domain CU254_RS12285 a313d1143d0dad7e27ac3ea7f3a5b3cb 367 Gene3D G3DSA:3.90.1720.10 217 361 2.2E-11 T 28-03-2018 CU254_RS12285 a313d1143d0dad7e27ac3ea7f3a5b3cb 367 Gene3D G3DSA:1.10.287.850 19 110 0.018 T 28-03-2018 CU254_RS30720 0adc7815e8e69cd22d184af49470781c 266 SUPERFAMILY SSF53474 3 264 1.99E-30 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS30720 0adc7815e8e69cd22d184af49470781c 266 Gene3D G3DSA:3.40.50.1820 2 264 9.9E-40 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS30720 0adc7815e8e69cd22d184af49470781c 266 Pfam PF12697 Alpha/beta hydrolase family 24 250 2.0E-15 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS07165 84fac57ce8e226d23b27f4d27a415fec 717 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 25 681 1.5E-207 T 28-03-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 CU254_RS07165 84fac57ce8e226d23b27f4d27a415fec 717 Pfam PF00270 DEAD/DEAH box helicase 287 441 1.9E-17 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CU254_RS07165 84fac57ce8e226d23b27f4d27a415fec 717 SUPERFAMILY SSF50249 13 176 1.54E-28 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CU254_RS07165 84fac57ce8e226d23b27f4d27a415fec 717 SMART SM00490 521 605 3.5E-20 T 28-03-2018 IPR001650 Helicase, C-terminal CU254_RS07165 84fac57ce8e226d23b27f4d27a415fec 717 SUPERFAMILY SSF52540 181 459 1.39E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS07165 84fac57ce8e226d23b27f4d27a415fec 717 Pfam PF00271 Helicase conserved C-terminal domain 490 604 1.2E-18 T 28-03-2018 IPR001650 Helicase, C-terminal CU254_RS07165 84fac57ce8e226d23b27f4d27a415fec 717 Gene3D G3DSA:2.40.50.140 43 142 3.4E-23 T 28-03-2018 CU254_RS07165 84fac57ce8e226d23b27f4d27a415fec 717 Gene3D G3DSA:3.40.50.300 467 646 7.4E-30 T 28-03-2018 CU254_RS07165 84fac57ce8e226d23b27f4d27a415fec 717 SUPERFAMILY SSF52540 395 615 1.42E-36 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS07165 84fac57ce8e226d23b27f4d27a415fec 717 Gene3D G3DSA:3.40.50.300 246 462 1.7E-36 T 28-03-2018 CU254_RS07165 84fac57ce8e226d23b27f4d27a415fec 717 SMART SM00487 261 465 2.9E-29 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CU254_RS07165 84fac57ce8e226d23b27f4d27a415fec 717 Pfam PF17191 RecG wedge domain 13 173 5.1E-17 T 28-03-2018 IPR033454 RecG, wedge domain CU254_RS15140 c86d2b23fb13ff5f6f990ebe21e45de0 542 SUPERFAMILY SSF54373 299 484 5.4E-44 T 28-03-2018 CU254_RS15140 c86d2b23fb13ff5f6f990ebe21e45de0 542 Pfam PF00732 GMC oxidoreductase 12 304 5.9E-77 T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CU254_RS15140 c86d2b23fb13ff5f6f990ebe21e45de0 542 PIRSF PIRSF000137 1 542 1.1E-131 T 28-03-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CU254_RS15140 c86d2b23fb13ff5f6f990ebe21e45de0 542 Gene3D G3DSA:4.10.450.10 57 113 6.2E-24 T 28-03-2018 CU254_RS15140 c86d2b23fb13ff5f6f990ebe21e45de0 542 SUPERFAMILY SSF51905 483 540 1.68E-77 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS15140 c86d2b23fb13ff5f6f990ebe21e45de0 542 SUPERFAMILY SSF51905 8 297 1.68E-77 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS15140 c86d2b23fb13ff5f6f990ebe21e45de0 542 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 91 114 - T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CU254_RS15140 c86d2b23fb13ff5f6f990ebe21e45de0 542 Gene3D G3DSA:3.30.560.10 114 496 8.0E-88 T 28-03-2018 CU254_RS15140 c86d2b23fb13ff5f6f990ebe21e45de0 542 Pfam PF05199 GMC oxidoreductase 399 532 2.7E-37 T 28-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 CU254_RS15140 c86d2b23fb13ff5f6f990ebe21e45de0 542 Gene3D G3DSA:3.40.50.720 2 56 2.6E-5 T 28-03-2018 CU254_RS14025 a44b444bdd3415ed4b5683c4b2532002 235 Pfam PF08445 FR47-like protein 136 221 6.3E-23 T 28-03-2018 IPR013653 FR47-like GO:0016747 CU254_RS14025 a44b444bdd3415ed4b5683c4b2532002 235 SUPERFAMILY SSF55729 99 219 4.63E-19 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS14025 a44b444bdd3415ed4b5683c4b2532002 235 Gene3D G3DSA:3.40.630.30 9 221 3.1E-18 T 28-03-2018 CU254_RS09875 8ed95b707b84522ec200feb13ebac9f3 240 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 12 71 7.1E-21 T 28-03-2018 IPR022687 DTXR-type HTH domain GO:0003677 CU254_RS09875 8ed95b707b84522ec200feb13ebac9f3 240 Gene3D G3DSA:1.10.10.10 10 82 9.8E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS09875 8ed95b707b84522ec200feb13ebac9f3 240 Gene3D G3DSA:2.30.30.90 139 237 1.5E-18 T 28-03-2018 CU254_RS09875 8ed95b707b84522ec200feb13ebac9f3 240 Pfam PF04023 FeoA domain 171 222 6.3E-5 T 28-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CU254_RS09875 8ed95b707b84522ec200feb13ebac9f3 240 SMART SM00529 35 134 1.0E-41 T 28-03-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 CU254_RS09875 8ed95b707b84522ec200feb13ebac9f3 240 SUPERFAMILY SSF46785 11 71 1.21E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS09875 8ed95b707b84522ec200feb13ebac9f3 240 Gene3D G3DSA:1.10.60.10 84 138 6.7E-26 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CU254_RS09875 8ed95b707b84522ec200feb13ebac9f3 240 SUPERFAMILY SSF47979 74 146 1.96E-25 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CU254_RS09875 8ed95b707b84522ec200feb13ebac9f3 240 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 74 142 6.8E-28 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CU254_RS09875 8ed95b707b84522ec200feb13ebac9f3 240 SUPERFAMILY SSF50037 139 226 2.75E-16 T 28-03-2018 IPR008988 Transcriptional repressor, C-terminal CU254_RS33515 81f92ff4b71a91572f70f51b628421d2 571 PRINTS PR00723 Subtilisin serine protease family (S8) signature 160 179 1.4E-20 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CU254_RS33515 81f92ff4b71a91572f70f51b628421d2 571 PRINTS PR00723 Subtilisin serine protease family (S8) signature 473 489 1.4E-20 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CU254_RS33515 81f92ff4b71a91572f70f51b628421d2 571 PRINTS PR00723 Subtilisin serine protease family (S8) signature 220 233 1.4E-20 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CU254_RS33515 81f92ff4b71a91572f70f51b628421d2 571 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 165 176 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CU254_RS33515 81f92ff4b71a91572f70f51b628421d2 571 SUPERFAMILY SSF52743 143 183 9.3E-59 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS33515 81f92ff4b71a91572f70f51b628421d2 571 SUPERFAMILY SSF52743 215 339 9.3E-59 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS33515 81f92ff4b71a91572f70f51b628421d2 571 SUPERFAMILY SSF52743 366 564 9.3E-59 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS33515 81f92ff4b71a91572f70f51b628421d2 571 Pfam PF00082 Subtilase family 161 527 3.2E-41 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS33515 81f92ff4b71a91572f70f51b628421d2 571 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 224 234 - T 28-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site CU254_RS33515 81f92ff4b71a91572f70f51b628421d2 571 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 474 484 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CU254_RS33515 81f92ff4b71a91572f70f51b628421d2 571 Gene3D G3DSA:3.40.50.200 105 568 1.1E-64 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS24800 99f6cd82013d4329c1125cbb2b61dce0 337 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 144 174 - T 28-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 CU254_RS24800 99f6cd82013d4329c1125cbb2b61dce0 337 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 49 66 - T 28-03-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CU254_RS24800 99f6cd82013d4329c1125cbb2b61dce0 337 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 16 292 6.9E-76 T 28-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CU254_RS24800 99f6cd82013d4329c1125cbb2b61dce0 337 Pfam PF00701 Dihydrodipicolinate synthetase family 13 295 6.2E-79 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CU254_RS24800 99f6cd82013d4329c1125cbb2b61dce0 337 SUPERFAMILY SSF51569 12 296 4.4E-88 T 28-03-2018 CU254_RS24800 99f6cd82013d4329c1125cbb2b61dce0 337 PIRSF PIRSF001365 10 300 1.3E-77 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CU254_RS24800 99f6cd82013d4329c1125cbb2b61dce0 337 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 12 296 55.247 T 28-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CU254_RS24800 99f6cd82013d4329c1125cbb2b61dce0 337 Gene3D G3DSA:3.20.20.70 9 316 2.0E-88 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS24800 99f6cd82013d4329c1125cbb2b61dce0 337 PRINTS PR00146 Dihydrodipicolinate synthase signature 46 67 2.0E-28 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CU254_RS24800 99f6cd82013d4329c1125cbb2b61dce0 337 PRINTS PR00146 Dihydrodipicolinate synthase signature 139 156 2.0E-28 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CU254_RS24800 99f6cd82013d4329c1125cbb2b61dce0 337 PRINTS PR00146 Dihydrodipicolinate synthase signature 114 130 2.0E-28 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CU254_RS24800 99f6cd82013d4329c1125cbb2b61dce0 337 PRINTS PR00146 Dihydrodipicolinate synthase signature 82 100 2.0E-28 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CU254_RS24800 99f6cd82013d4329c1125cbb2b61dce0 337 SMART SM01130 12 298 2.0E-110 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CU254_RS23195 c4f4228ee5751bf67f7817d54d579e2b 317 Gene3D G3DSA:1.20.58.340 251 317 3.4E-13 T 28-03-2018 CU254_RS23195 c4f4228ee5751bf67f7817d54d579e2b 317 Gene3D G3DSA:3.30.460.20 1 124 8.6E-27 T 28-03-2018 CU254_RS23195 c4f4228ee5751bf67f7817d54d579e2b 317 Gene3D G3DSA:1.20.58.340 131 250 1.8E-31 T 28-03-2018 CU254_RS23195 c4f4228ee5751bf67f7817d54d579e2b 317 SUPERFAMILY SSF144083 253 314 1.44E-14 T 28-03-2018 CU254_RS23195 c4f4228ee5751bf67f7817d54d579e2b 317 Pfam PF01544 CorA-like Mg2+ transporter protein 26 313 2.7E-67 T 28-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 CU254_RS23195 c4f4228ee5751bf67f7817d54d579e2b 317 SUPERFAMILY SSF143865 7 252 1.02E-64 T 28-03-2018 CU254_RS27490 57cc18536f81d8505c304b1186fb5065 245 SUPERFAMILY SSF142823 10 241 1.7E-34 T 28-03-2018 IPR005238 ComB-like GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 CU254_RS27490 57cc18536f81d8505c304b1186fb5065 245 Gene3D G3DSA:3.90.1560.10 18 244 2.7E-50 T 28-03-2018 IPR005238 ComB-like GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 CU254_RS27490 57cc18536f81d8505c304b1186fb5065 245 Pfam PF04029 2-phosphosulpholactate phosphatase 29 238 5.1E-17 T 28-03-2018 IPR005238 ComB-like GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 CU254_RS18080 27baa1d9d5ac6ac6ce02f3377063cdfa 347 Gene3D G3DSA:3.40.50.1400 156 293 2.5E-44 T 28-03-2018 CU254_RS18080 27baa1d9d5ac6ac6ce02f3377063cdfa 347 TIGRFAM TIGR00109 hemH: ferrochelatase 39 311 2.1E-40 T 28-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CU254_RS18080 27baa1d9d5ac6ac6ce02f3377063cdfa 347 SUPERFAMILY SSF53800 3 316 4.25E-83 T 28-03-2018 CU254_RS18080 27baa1d9d5ac6ac6ce02f3377063cdfa 347 Gene3D G3DSA:3.40.50.1400 2 155 1.2E-32 T 28-03-2018 CU254_RS18080 27baa1d9d5ac6ac6ce02f3377063cdfa 347 Pfam PF00762 Ferrochelatase 4 311 5.8E-97 T 28-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CU254_RS18080 27baa1d9d5ac6ac6ce02f3377063cdfa 347 Hamap MF_00323 Ferrochelatase [hemH]. 2 311 30.679 T 28-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CU254_RS28505 629c732817eb50667e4fed6248c202ff 383 Gene3D G3DSA:3.40.1010.10 6 114 1.5E-14 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CU254_RS28505 629c732817eb50667e4fed6248c202ff 383 Gene3D G3DSA:3.30.950.10 115 199 1.2E-15 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CU254_RS28505 629c732817eb50667e4fed6248c202ff 383 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 7 180 6.3E-23 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CU254_RS28505 629c732817eb50667e4fed6248c202ff 383 TIGRFAM TIGR02469 CbiT: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit 218 325 8.5E-26 T 28-03-2018 IPR014008 Cobalamin biosynthesis, precorrin-6Y methyltransferase, CbiT subunit GO:0008276|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.196|MetaCyc: PWY-2201|MetaCyc: PWY-7377 CU254_RS28505 629c732817eb50667e4fed6248c202ff 383 SUPERFAMILY SSF53335 205 361 2.24E-22 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS28505 629c732817eb50667e4fed6248c202ff 383 SUPERFAMILY SSF53790 8 186 3.53E-30 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CU254_RS28505 629c732817eb50667e4fed6248c202ff 383 Gene3D G3DSA:3.40.50.150 212 383 1.8E-24 T 28-03-2018 CU254_RS28505 629c732817eb50667e4fed6248c202ff 383 PIRSF PIRSF036428 3 383 1.1E-108 T 28-03-2018 IPR006365 Cobalamin (vitamin B12) biosynthesis CobL/Precorrin-6Y C(5,15)-methyltransferase GO:0008276|GO:0009236 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|KEGG: 00860+2.1.1.132|MetaCyc: PWY-2201|MetaCyc: PWY-3841 CU254_RS28505 629c732817eb50667e4fed6248c202ff 383 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 10 185 2.7E-37 T 28-03-2018 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 CU254_RS15290 21583f4237ba52e8698792116400d515 509 Gene3D G3DSA:2.30.38.10 333 410 2.8E-19 T 28-03-2018 CU254_RS15290 21583f4237ba52e8698792116400d515 509 Pfam PF13193 AMP-binding enzyme C-terminal domain 425 499 5.6E-23 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS15290 21583f4237ba52e8698792116400d515 509 SUPERFAMILY SSF56801 6 508 3.27E-131 T 28-03-2018 CU254_RS15290 21583f4237ba52e8698792116400d515 509 Pfam PF00501 AMP-binding enzyme 29 416 1.5E-87 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS15290 21583f4237ba52e8698792116400d515 509 Gene3D G3DSA:3.40.50.980 11 165 1.1E-34 T 28-03-2018 CU254_RS15290 21583f4237ba52e8698792116400d515 509 Gene3D G3DSA:3.30.300.30 412 509 4.5E-28 T 28-03-2018 CU254_RS15290 21583f4237ba52e8698792116400d515 509 Gene3D G3DSA:3.40.50.980 166 314 5.7E-34 T 28-03-2018 CU254_RS41405 e92ffaa183c2a2a2d397e6d2220a579f 606 SUPERFAMILY SSF52402 191 340 3.91E-22 T 28-03-2018 CU254_RS41405 e92ffaa183c2a2a2d397e6d2220a579f 606 SUPERFAMILY SSF52402 442 559 3.91E-22 T 28-03-2018 CU254_RS41405 e92ffaa183c2a2a2d397e6d2220a579f 606 Pfam PF00733 Asparagine synthase 194 585 7.1E-26 T 28-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 CU254_RS41405 e92ffaa183c2a2a2d397e6d2220a579f 606 Gene3D G3DSA:3.40.50.620 186 567 1.2E-30 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS41405 e92ffaa183c2a2a2d397e6d2220a579f 606 SUPERFAMILY SSF56235 63 183 2.19E-10 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CU254_RS41405 e92ffaa183c2a2a2d397e6d2220a579f 606 Gene3D G3DSA:3.60.20.10 57 185 4.8E-5 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CU254_RS13795 7ed71092f3947ab8315ce321eddee6ae 508 PRINTS PR00067 Catalase signature 107 124 1.6E-66 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CU254_RS13795 7ed71092f3947ab8315ce321eddee6ae 508 PRINTS PR00067 Catalase signature 86 104 1.6E-66 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CU254_RS13795 7ed71092f3947ab8315ce321eddee6ae 508 PRINTS PR00067 Catalase signature 291 318 1.6E-66 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CU254_RS13795 7ed71092f3947ab8315ce321eddee6ae 508 PRINTS PR00067 Catalase signature 126 144 1.6E-66 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CU254_RS13795 7ed71092f3947ab8315ce321eddee6ae 508 PRINTS PR00067 Catalase signature 24 47 1.6E-66 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CU254_RS13795 7ed71092f3947ab8315ce321eddee6ae 508 PRINTS PR00067 Catalase signature 323 349 1.6E-66 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CU254_RS13795 7ed71092f3947ab8315ce321eddee6ae 508 Pfam PF06628 Catalase-related immune-responsive 420 482 1.6E-18 T 28-03-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CU254_RS13795 7ed71092f3947ab8315ce321eddee6ae 508 PIRSF PIRSF038928 1 488 1.8E-234 T 28-03-2018 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CU254_RS13795 7ed71092f3947ab8315ce321eddee6ae 508 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 336 344 - T 28-03-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CU254_RS13795 7ed71092f3947ab8315ce321eddee6ae 508 Gene3D G3DSA:2.40.180.10 1 360 2.5E-162 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CU254_RS13795 7ed71092f3947ab8315ce321eddee6ae 508 SMART SM01060 11 392 1.1E-278 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CU254_RS13795 7ed71092f3947ab8315ce321eddee6ae 508 SUPERFAMILY SSF56634 5 492 7.59E-204 T 28-03-2018 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CU254_RS13795 7ed71092f3947ab8315ce321eddee6ae 508 ProSitePatterns PS00438 Catalase proximal active site signature. 47 63 - T 28-03-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CU254_RS13795 7ed71092f3947ab8315ce321eddee6ae 508 Pfam PF00199 Catalase 11 388 1.1E-185 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CU254_RS23200 8a85a25dcd1ae7e8d2ed4bbd4531c11a 237 Gene3D G3DSA:1.25.40.20 2 138 8.0E-27 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain CU254_RS23200 8a85a25dcd1ae7e8d2ed4bbd4531c11a 237 SMART SM00248 168 197 260.0 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 CU254_RS23200 8a85a25dcd1ae7e8d2ed4bbd4531c11a 237 SMART SM00248 42 76 0.094 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 CU254_RS23200 8a85a25dcd1ae7e8d2ed4bbd4531c11a 237 SMART SM00248 80 109 0.0026 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 CU254_RS23200 8a85a25dcd1ae7e8d2ed4bbd4531c11a 237 SMART SM00248 5 34 780.0 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 CU254_RS23200 8a85a25dcd1ae7e8d2ed4bbd4531c11a 237 SMART SM00248 113 142 1900.0 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 CU254_RS23200 8a85a25dcd1ae7e8d2ed4bbd4531c11a 237 Pfam PF12796 Ankyrin repeats (3 copies) 61 140 9.1E-8 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain CU254_RS23200 8a85a25dcd1ae7e8d2ed4bbd4531c11a 237 SUPERFAMILY SSF48403 10 219 2.49E-26 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain CU254_RS23200 8a85a25dcd1ae7e8d2ed4bbd4531c11a 237 Gene3D G3DSA:1.25.40.20 139 237 3.9E-7 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain CU254_RS42385 b2e18f462c609c5256b607d91fa67771 269 SUPERFAMILY SSF52540 4 31 8.8E-8 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS42385 b2e18f462c609c5256b607d91fa67771 269 SUPERFAMILY SSF52540 68 256 1.28E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS42385 b2e18f462c609c5256b607d91fa67771 269 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 8 225 1.2E-8 T 28-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CU254_RS42385 b2e18f462c609c5256b607d91fa67771 269 Gene3D G3DSA:3.40.50.300 4 259 9.5E-26 T 28-03-2018 CU254_RS14205 6e73e57c64a3dab4b184e3be3f605003 292 Gene3D G3DSA:1.10.10.10 4 84 7.9E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS14205 6e73e57c64a3dab4b184e3be3f605003 292 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 63 2.6E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS14205 6e73e57c64a3dab4b184e3be3f605003 292 SUPERFAMILY SSF46785 8 102 3.02E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS04510 1813bd0892a501d053e7fdb724a0822e 372 Pfam PF01384 Phosphate transporter family 17 312 3.9E-79 T 28-03-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 CU254_RS10590 2ced741b15231643b3b0b9cc4a9572b1 537 Pfam PF13193 AMP-binding enzyme C-terminal domain 446 521 1.7E-15 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS10590 2ced741b15231643b3b0b9cc4a9572b1 537 SUPERFAMILY SSF56801 5 533 1.96E-112 T 28-03-2018 CU254_RS10590 2ced741b15231643b3b0b9cc4a9572b1 537 Pfam PF00501 AMP-binding enzyme 16 435 2.5E-63 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS10590 2ced741b15231643b3b0b9cc4a9572b1 537 Gene3D G3DSA:3.40.50.980 9 177 2.8E-38 T 28-03-2018 CU254_RS10590 2ced741b15231643b3b0b9cc4a9572b1 537 ProSitePatterns PS00455 Putative AMP-binding domain signature. 173 184 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS10590 2ced741b15231643b3b0b9cc4a9572b1 537 Gene3D G3DSA:2.30.38.10 354 431 6.7E-8 T 28-03-2018 CU254_RS10590 2ced741b15231643b3b0b9cc4a9572b1 537 Gene3D G3DSA:3.30.300.30 432 536 3.8E-24 T 28-03-2018 CU254_RS10590 2ced741b15231643b3b0b9cc4a9572b1 537 Gene3D G3DSA:3.40.50.980 178 352 3.0E-28 T 28-03-2018 CU254_RS24215 5118eaea6dce327c095990523c33c58b 332 SUPERFAMILY SSF46785 37 109 9.37E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS24215 5118eaea6dce327c095990523c33c58b 332 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 37 88 1.5E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS24215 5118eaea6dce327c095990523c33c58b 332 Gene3D G3DSA:1.10.10.10 33 108 9.9E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS24215 5118eaea6dce327c095990523c33c58b 332 Gene3D G3DSA:3.40.190.10 114 200 1.7E-9 T 28-03-2018 CU254_RS24215 5118eaea6dce327c095990523c33c58b 332 Gene3D G3DSA:3.40.190.10 201 294 0.0021 T 28-03-2018 CU254_RS24215 5118eaea6dce327c095990523c33c58b 332 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 8.6E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS24215 5118eaea6dce327c095990523c33c58b 332 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 55 65 8.6E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS24215 5118eaea6dce327c095990523c33c58b 332 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 65 76 8.6E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS24215 5118eaea6dce327c095990523c33c58b 332 SUPERFAMILY SSF53850 117 312 1.19E-9 T 28-03-2018 CU254_RS24215 5118eaea6dce327c095990523c33c58b 332 Pfam PF03466 LysR substrate binding domain 151 312 1.3E-8 T 28-03-2018 IPR005119 LysR, substrate-binding CU254_RS35725 6b1083da5d77e014617e2ae2a736c3a2 167 Gene3D G3DSA:3.10.180.10 33 165 2.8E-24 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS35725 6b1083da5d77e014617e2ae2a736c3a2 167 SUPERFAMILY SSF54593 35 162 3.36E-29 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS35725 6b1083da5d77e014617e2ae2a736c3a2 167 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 36 153 1.1E-12 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CU254_RS12095 edab63fcd3014884cfd0dab139ecd909 644 Pfam PF00326 Prolyl oligopeptidase family 428 640 1.4E-52 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CU254_RS12095 edab63fcd3014884cfd0dab139ecd909 644 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 466 485 8.4E-48 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CU254_RS12095 edab63fcd3014884cfd0dab139ecd909 644 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 551 566 8.4E-48 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CU254_RS12095 edab63fcd3014884cfd0dab139ecd909 644 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 570 592 8.4E-48 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CU254_RS12095 edab63fcd3014884cfd0dab139ecd909 644 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 438 462 8.4E-48 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CU254_RS12095 edab63fcd3014884cfd0dab139ecd909 644 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 412 430 8.4E-48 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CU254_RS12095 edab63fcd3014884cfd0dab139ecd909 644 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 496 516 8.4E-48 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CU254_RS12095 edab63fcd3014884cfd0dab139ecd909 644 SUPERFAMILY SSF50993 3 372 4.71E-64 T 28-03-2018 CU254_RS12095 edab63fcd3014884cfd0dab139ecd909 644 Gene3D G3DSA:3.40.50.1820 363 644 1.0E-42 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS12095 edab63fcd3014884cfd0dab139ecd909 644 ProSitePatterns PS00708 Prolyl endopeptidase family serine active site. 473 503 - T 28-03-2018 IPR002471 Peptidase S9, serine active site GO:0004252|GO:0006508 CU254_RS12095 edab63fcd3014884cfd0dab139ecd909 644 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 8 373 8.5E-61 T 28-03-2018 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 CU254_RS12095 edab63fcd3014884cfd0dab139ecd909 644 SUPERFAMILY SSF53474 387 638 4.44E-48 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS12095 edab63fcd3014884cfd0dab139ecd909 644 Gene3D G3DSA:2.130.10.120 68 362 5.7E-47 T 28-03-2018 CU254_RS18145 ebeab7edc7a15d5d6645d4fab4d592ee 212 Gene3D G3DSA:3.40.50.1000 66 196 1.0E-24 T 28-03-2018 IPR023214 HAD-like domain CU254_RS18145 ebeab7edc7a15d5d6645d4fab4d592ee 212 Gene3D G3DSA:1.10.150.240 7 65 3.7E-15 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CU254_RS18145 ebeab7edc7a15d5d6645d4fab4d592ee 212 Pfam PF13419 Haloacid dehalogenase-like hydrolase 1 179 6.8E-23 T 28-03-2018 IPR023214 HAD-like domain CU254_RS18145 ebeab7edc7a15d5d6645d4fab4d592ee 212 SUPERFAMILY SSF56784 1 183 3.92E-43 T 28-03-2018 IPR023214 HAD-like domain CU254_RS18145 ebeab7edc7a15d5d6645d4fab4d592ee 212 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 74 179 4.0E-14 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CU254_RS36475 a840c76566702bcee525c1209276cd53 957 Gene3D G3DSA:2.70.20.10 370 502 3.4E-37 T 28-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 CU254_RS36475 a840c76566702bcee525c1209276cd53 957 SMART SM00493 19 133 1.4E-36 T 28-03-2018 IPR006171 TOPRIM domain CU254_RS36475 a840c76566702bcee525c1209276cd53 957 Pfam PF13368 Topoisomerase C-terminal repeat 648 699 3.5E-8 T 28-03-2018 IPR025589 Topoisomerase C-terminal repeat CU254_RS36475 a840c76566702bcee525c1209276cd53 957 Pfam PF13368 Topoisomerase C-terminal repeat 784 837 5.2E-17 T 28-03-2018 IPR025589 Topoisomerase C-terminal repeat CU254_RS36475 a840c76566702bcee525c1209276cd53 957 Pfam PF13368 Topoisomerase C-terminal repeat 706 779 7.2E-13 T 28-03-2018 IPR025589 Topoisomerase C-terminal repeat CU254_RS36475 a840c76566702bcee525c1209276cd53 957 Pfam PF13368 Topoisomerase C-terminal repeat 851 903 1.7E-20 T 28-03-2018 IPR025589 Topoisomerase C-terminal repeat CU254_RS36475 a840c76566702bcee525c1209276cd53 957 Gene3D G3DSA:3.40.50.140 18 158 5.8E-40 T 28-03-2018 CU254_RS36475 a840c76566702bcee525c1209276cd53 957 SUPERFAMILY SSF56712 19 605 5.89E-175 T 28-03-2018 IPR023405 DNA topoisomerase, type IA, core domain CU254_RS36475 a840c76566702bcee525c1209276cd53 957 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 331 345 - T 28-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 CU254_RS36475 a840c76566702bcee525c1209276cd53 957 SMART SM00437 294 564 2.3E-120 T 28-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 CU254_RS36475 a840c76566702bcee525c1209276cd53 957 Gene3D G3DSA:1.10.460.10 503 956 1.1E-28 T 28-03-2018 CU254_RS36475 a840c76566702bcee525c1209276cd53 957 Hamap MF_00952 DNA topoisomerase 1 [topA]. 19 796 53.693 T 28-03-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 CU254_RS36475 a840c76566702bcee525c1209276cd53 957 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 191 209 1.0E-35 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CU254_RS36475 a840c76566702bcee525c1209276cd53 957 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 107 120 1.0E-35 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CU254_RS36475 a840c76566702bcee525c1209276cd53 957 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 527 541 1.0E-35 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CU254_RS36475 a840c76566702bcee525c1209276cd53 957 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 336 345 1.0E-35 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CU254_RS36475 a840c76566702bcee525c1209276cd53 957 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 415 431 1.0E-35 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CU254_RS36475 a840c76566702bcee525c1209276cd53 957 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 21 676 1.1E-248 T 28-03-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 CU254_RS36475 a840c76566702bcee525c1209276cd53 957 Gene3D G3DSA:1.10.460.10 164 369 4.3E-44 T 28-03-2018 CU254_RS36475 a840c76566702bcee525c1209276cd53 957 Pfam PF01751 Toprim domain 21 142 1.2E-28 T 28-03-2018 IPR006171 TOPRIM domain CU254_RS36475 a840c76566702bcee525c1209276cd53 957 Pfam PF01131 DNA topoisomerase 157 601 1.7E-120 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CU254_RS36475 a840c76566702bcee525c1209276cd53 957 SMART SM00436 133 221 7.5E-42 T 28-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 CU254_RS06840 ce459d7f4f5df2622f3b082afb9c00f0 614 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 511 522 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CU254_RS06840 ce459d7f4f5df2622f3b082afb9c00f0 614 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 611 2.2E-236 T 28-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CU254_RS06840 ce459d7f4f5df2622f3b082afb9c00f0 614 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 4 611 44.72 T 28-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CU254_RS06840 ce459d7f4f5df2622f3b082afb9c00f0 614 Gene3D G3DSA:3.40.50.2300 61 182 1.8E-4 T 28-03-2018 CU254_RS06840 ce459d7f4f5df2622f3b082afb9c00f0 614 Pfam PF00920 Dehydratase family 34 608 2.8E-214 T 28-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CU254_RS06840 ce459d7f4f5df2622f3b082afb9c00f0 614 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 122 132 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CU254_RS06840 ce459d7f4f5df2622f3b082afb9c00f0 614 SUPERFAMILY SSF143975 4 422 2.09E-133 T 28-03-2018 CU254_RS06840 ce459d7f4f5df2622f3b082afb9c00f0 614 SUPERFAMILY SSF52016 423 612 1.33E-58 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CU254_RS24930 37916e3e50f8f1c39f6397fb780fce7e 336 Pfam PF02272 DHHA1 domain 245 327 3.7E-11 T 28-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CU254_RS24930 37916e3e50f8f1c39f6397fb780fce7e 336 Pfam PF01368 DHH family 22 168 1.9E-10 T 28-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CU254_RS24930 37916e3e50f8f1c39f6397fb780fce7e 336 SUPERFAMILY SSF64182 23 327 2.49E-51 T 28-03-2018 CU254_RS24930 37916e3e50f8f1c39f6397fb780fce7e 336 Gene3D G3DSA:3.90.1640.10 2 207 1.1E-31 T 28-03-2018 CU254_RS10145 d8511e2c75008896234ca0f70e3e0ab8 408 ProSitePatterns PS01095 Chitinases family 18 active site. 177 185 - T 28-03-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 CU254_RS10145 d8511e2c75008896234ca0f70e3e0ab8 408 SMART SM00636 43 396 1.4E-115 T 28-03-2018 IPR011583 Chitinase II GO:0008061 CU254_RS10145 d8511e2c75008896234ca0f70e3e0ab8 408 Gene3D G3DSA:3.20.20.80 14 408 9.4E-93 T 28-03-2018 CU254_RS10145 d8511e2c75008896234ca0f70e3e0ab8 408 SUPERFAMILY SSF54556 308 367 1.79E-13 T 28-03-2018 IPR029070 Chitinase insertion domain CU254_RS10145 d8511e2c75008896234ca0f70e3e0ab8 408 SUPERFAMILY SSF51445 366 402 1.05E-87 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS10145 d8511e2c75008896234ca0f70e3e0ab8 408 SUPERFAMILY SSF51445 40 306 1.05E-87 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS10145 d8511e2c75008896234ca0f70e3e0ab8 408 Pfam PF00704 Glycosyl hydrolases family 18 44 396 5.4E-76 T 28-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 CU254_RS30065 e5f25a3ee65e0716e589b3d72cb82404 846 Pfam PF02687 FtsX-like permease family 295 389 7.5E-10 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CU254_RS30065 e5f25a3ee65e0716e589b3d72cb82404 846 Pfam PF02687 FtsX-like permease family 748 836 2.1E-8 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CU254_RS12410 dff691ba1da3de4d54eb802032dc94d5 452 SMART SM00878 335 441 9.2E-55 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CU254_RS12410 dff691ba1da3de4d54eb802032dc94d5 452 Gene3D G3DSA:3.40.50.20 1 122 6.2E-52 T 28-03-2018 CU254_RS12410 dff691ba1da3de4d54eb802032dc94d5 452 Gene3D G3DSA:3.30.470.20 209 444 1.4E-97 T 28-03-2018 CU254_RS12410 dff691ba1da3de4d54eb802032dc94d5 452 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 114 321 4.3E-75 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CU254_RS12410 dff691ba1da3de4d54eb802032dc94d5 452 Gene3D G3DSA:3.30.1490.20 123 208 9.9E-24 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CU254_RS12410 dff691ba1da3de4d54eb802032dc94d5 452 SUPERFAMILY SSF56059 82 347 2.3E-67 T 28-03-2018 CU254_RS12410 dff691ba1da3de4d54eb802032dc94d5 452 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 152 166 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CU254_RS12410 dff691ba1da3de4d54eb802032dc94d5 452 SUPERFAMILY SSF52440 2 112 2.01E-44 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CU254_RS12410 dff691ba1da3de4d54eb802032dc94d5 452 SUPERFAMILY SSF51246 330 445 1.46E-39 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CU254_RS12410 dff691ba1da3de4d54eb802032dc94d5 452 Pfam PF02785 Biotin carboxylase C-terminal domain 335 442 4.7E-37 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CU254_RS12410 dff691ba1da3de4d54eb802032dc94d5 452 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 285 292 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CU254_RS12410 dff691ba1da3de4d54eb802032dc94d5 452 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 109 2.9E-42 T 28-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CU254_RS14925 29abd954dc0d4283f32c6d34f478a063 312 Gene3D G3DSA:3.40.630.30 3 154 0.14 T 28-03-2018 CU254_RS14925 29abd954dc0d4283f32c6d34f478a063 312 SUPERFAMILY SSF55729 4 304 4.46E-23 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS14925 29abd954dc0d4283f32c6d34f478a063 312 Pfam PF00583 Acetyltransferase (GNAT) family 216 299 1.9E-7 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS14925 29abd954dc0d4283f32c6d34f478a063 312 Gene3D G3DSA:3.40.630.30 155 305 1.7E-19 T 28-03-2018 CU254_RS38255 04e54fe2f51ff2e6be4e76bfa4dde6c2 401 Gene3D G3DSA:1.50.10.10 21 384 2.6E-66 T 28-03-2018 CU254_RS38255 04e54fe2f51ff2e6be4e76bfa4dde6c2 401 SUPERFAMILY SSF48208 47 379 1.9E-62 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CU254_RS38255 04e54fe2f51ff2e6be4e76bfa4dde6c2 401 Pfam PF07470 Glycosyl Hydrolase Family 88 36 377 1.1E-77 T 28-03-2018 IPR010905 Glycosyl hydrolase, family 88 CU254_RS15925 125b36c1250a2def917011c21a6cf568 346 Gene3D G3DSA:3.30.70.1350 255 339 5.7E-18 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CU254_RS15925 125b36c1250a2def917011c21a6cf568 346 SUPERFAMILY SSF160240 258 336 3.66E-15 T 28-03-2018 CU254_RS15925 125b36c1250a2def917011c21a6cf568 346 SUPERFAMILY SSF161111 57 257 5.89E-47 T 28-03-2018 CU254_RS15925 125b36c1250a2def917011c21a6cf568 346 Pfam PF16916 Dimerisation domain of Zinc Transporter 260 337 7.2E-15 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CU254_RS15925 125b36c1250a2def917011c21a6cf568 346 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 61 337 3.6E-64 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CU254_RS15925 125b36c1250a2def917011c21a6cf568 346 Gene3D G3DSA:1.20.1510.10 60 254 4.4E-36 T 28-03-2018 CU254_RS15925 125b36c1250a2def917011c21a6cf568 346 Pfam PF01545 Cation efflux family 63 256 2.8E-39 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CU254_RS21450 ca89db9c6f278abbd5c5e6d77c31f548 792 SUPERFAMILY SSF109604 68 254 8.47E-71 T 28-03-2018 CU254_RS21450 ca89db9c6f278abbd5c5e6d77c31f548 792 SUPERFAMILY SSF81271 442 514 3.49E-21 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CU254_RS21450 ca89db9c6f278abbd5c5e6d77c31f548 792 Pfam PF02824 TGS domain 455 514 1.2E-22 T 28-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 CU254_RS21450 ca89db9c6f278abbd5c5e6d77c31f548 792 Gene3D G3DSA:3.10.20.30 449 521 6.7E-27 T 28-03-2018 IPR012675 Beta-grasp domain CU254_RS21450 ca89db9c6f278abbd5c5e6d77c31f548 792 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 92 787 3.3E-264 T 28-03-2018 IPR004811 RelA/SpoT family GO:0015969 CU254_RS21450 ca89db9c6f278abbd5c5e6d77c31f548 792 Pfam PF04607 Region found in RelA / SpoT proteins 299 408 1.2E-35 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 CU254_RS21450 ca89db9c6f278abbd5c5e6d77c31f548 792 SMART SM00471 107 217 9.7E-13 T 28-03-2018 IPR003607 HD/PDEase domain CU254_RS21450 ca89db9c6f278abbd5c5e6d77c31f548 792 Pfam PF13291 ACT domain 711 787 4.5E-16 T 28-03-2018 IPR002912 ACT domain CU254_RS21450 ca89db9c6f278abbd5c5e6d77c31f548 792 SUPERFAMILY SSF81301 244 459 6.87E-60 T 28-03-2018 CU254_RS21450 ca89db9c6f278abbd5c5e6d77c31f548 792 Gene3D G3DSA:3.30.460.10 252 390 2.3E-41 T 28-03-2018 CU254_RS21450 ca89db9c6f278abbd5c5e6d77c31f548 792 Pfam PF13328 HD domain 92 239 7.8E-49 T 28-03-2018 IPR003607 HD/PDEase domain CU254_RS21450 ca89db9c6f278abbd5c5e6d77c31f548 792 Gene3D G3DSA:3.30.70.260 715 792 2.2E-12 T 28-03-2018 CU254_RS21450 ca89db9c6f278abbd5c5e6d77c31f548 792 SUPERFAMILY SSF55021 711 789 1.46E-13 T 28-03-2018 CU254_RS21450 ca89db9c6f278abbd5c5e6d77c31f548 792 SMART SM00954 299 409 3.2E-60 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 CU254_RS05670 15b3c929c5871167dc2b6cb6ba6d42be 498 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 384 494 2.4E-33 T 28-03-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 CU254_RS05670 15b3c929c5871167dc2b6cb6ba6d42be 498 Gene3D G3DSA:3.20.20.10 22 247 4.5E-54 T 28-03-2018 IPR029066 PLP-binding barrel CU254_RS05670 15b3c929c5871167dc2b6cb6ba6d42be 498 SUPERFAMILY SSF56276 384 496 4.71E-32 T 28-03-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 CU254_RS05670 15b3c929c5871167dc2b6cb6ba6d42be 498 Gene3D G3DSA:3.60.90.10 387 498 1.6E-36 T 28-03-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 CU254_RS05670 15b3c929c5871167dc2b6cb6ba6d42be 498 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 43 61 8.7E-17 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CU254_RS05670 15b3c929c5871167dc2b6cb6ba6d42be 498 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 165 178 8.7E-17 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CU254_RS05670 15b3c929c5871167dc2b6cb6ba6d42be 498 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 63 75 8.7E-17 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CU254_RS05670 15b3c929c5871167dc2b6cb6ba6d42be 498 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 247 266 8.7E-17 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CU254_RS05670 15b3c929c5871167dc2b6cb6ba6d42be 498 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 382 498 25.217 T 28-03-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 CU254_RS05670 15b3c929c5871167dc2b6cb6ba6d42be 498 SUPERFAMILY SSF51419 21 259 7.85E-66 T 28-03-2018 IPR029066 PLP-binding barrel CU254_RS05670 15b3c929c5871167dc2b6cb6ba6d42be 498 Pfam PF02675 S-adenosylmethionine decarboxylase 388 494 1.0E-30 T 28-03-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 CU254_RS05670 15b3c929c5871167dc2b6cb6ba6d42be 498 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 245 352 1.0E-10 T 28-03-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 CU254_RS05670 15b3c929c5871167dc2b6cb6ba6d42be 498 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 43 61 - T 28-03-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site CU254_RS05670 15b3c929c5871167dc2b6cb6ba6d42be 498 PRINTS PR01182 Ornithine decarboxylase signature 115 137 6.7E-19 T 28-03-2018 IPR002433 Ornithine decarboxylase GO:0006596 CU254_RS05670 15b3c929c5871167dc2b6cb6ba6d42be 498 PRINTS PR01182 Ornithine decarboxylase signature 15 39 6.7E-19 T 28-03-2018 IPR002433 Ornithine decarboxylase GO:0006596 CU254_RS05670 15b3c929c5871167dc2b6cb6ba6d42be 498 PRINTS PR01182 Ornithine decarboxylase signature 41 68 6.7E-19 T 28-03-2018 IPR002433 Ornithine decarboxylase GO:0006596 CU254_RS05670 15b3c929c5871167dc2b6cb6ba6d42be 498 PRINTS PR01182 Ornithine decarboxylase signature 316 326 6.7E-19 T 28-03-2018 IPR002433 Ornithine decarboxylase GO:0006596 CU254_RS05670 15b3c929c5871167dc2b6cb6ba6d42be 498 PRINTS PR01182 Ornithine decarboxylase signature 85 109 6.7E-19 T 28-03-2018 IPR002433 Ornithine decarboxylase GO:0006596 CU254_RS05670 15b3c929c5871167dc2b6cb6ba6d42be 498 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 25 257 2.3E-51 T 28-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 CU254_RS05670 15b3c929c5871167dc2b6cb6ba6d42be 498 Gene3D G3DSA:2.40.37.10 248 386 2.6E-26 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CU254_RS05670 15b3c929c5871167dc2b6cb6ba6d42be 498 SUPERFAMILY SSF50621 238 376 1.76E-29 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CU254_RS30365 205afeeb9105aa21acbed44ee3e3665a 210 Hamap MF_00163 Peptide deformylase [def]. 14 192 25.623 T 28-03-2018 IPR023635 Peptide deformylase CU254_RS30365 205afeeb9105aa21acbed44ee3e3665a 210 Pfam PF01327 Polypeptide deformylase 17 180 9.3E-44 T 28-03-2018 IPR023635 Peptide deformylase CU254_RS30365 205afeeb9105aa21acbed44ee3e3665a 210 PIRSF PIRSF004749 3 205 1.3E-51 T 28-03-2018 IPR023635 Peptide deformylase CU254_RS30365 205afeeb9105aa21acbed44ee3e3665a 210 SUPERFAMILY SSF56420 10 179 1.7E-49 T 28-03-2018 IPR023635 Peptide deformylase CU254_RS30365 205afeeb9105aa21acbed44ee3e3665a 210 PRINTS PR01576 Peptide deformylase signature 151 180 6.4E-31 T 28-03-2018 IPR023635 Peptide deformylase CU254_RS30365 205afeeb9105aa21acbed44ee3e3665a 210 PRINTS PR01576 Peptide deformylase signature 47 76 6.4E-31 T 28-03-2018 IPR023635 Peptide deformylase CU254_RS30365 205afeeb9105aa21acbed44ee3e3665a 210 PRINTS PR01576 Peptide deformylase signature 132 150 6.4E-31 T 28-03-2018 IPR023635 Peptide deformylase CU254_RS30365 205afeeb9105aa21acbed44ee3e3665a 210 PRINTS PR01576 Peptide deformylase signature 120 131 6.4E-31 T 28-03-2018 IPR023635 Peptide deformylase CU254_RS30365 205afeeb9105aa21acbed44ee3e3665a 210 Gene3D G3DSA:3.90.45.10 1 204 1.2E-56 T 28-03-2018 IPR023635 Peptide deformylase CU254_RS38100 bd7e7cb3e474915bc88013b914caad7b 504 SUPERFAMILY SSF103473 4 197 1.31E-64 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS38100 bd7e7cb3e474915bc88013b914caad7b 504 SUPERFAMILY SSF103473 244 415 1.31E-64 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS38100 bd7e7cb3e474915bc88013b914caad7b 504 SUPERFAMILY SSF103473 461 495 1.31E-64 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS38100 bd7e7cb3e474915bc88013b914caad7b 504 Gene3D G3DSA:1.20.1250.20 248 502 8.8E-26 T 28-03-2018 CU254_RS38100 bd7e7cb3e474915bc88013b914caad7b 504 Pfam PF07690 Major Facilitator Superfamily 19 405 2.9E-50 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS38100 bd7e7cb3e474915bc88013b914caad7b 504 Gene3D G3DSA:1.20.1250.20 2 195 1.6E-31 T 28-03-2018 CU254_RS07310 f875d1fac1ba42642095a63883e83f49 160 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 2 157 33.804 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CU254_RS07310 f875d1fac1ba42642095a63883e83f49 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 49 73 1.1E-48 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CU254_RS07310 f875d1fac1ba42642095a63883e83f49 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 20 41 1.1E-48 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CU254_RS07310 f875d1fac1ba42642095a63883e83f49 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 111 133 1.1E-48 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CU254_RS07310 f875d1fac1ba42642095a63883e83f49 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 85 101 1.1E-48 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CU254_RS07310 f875d1fac1ba42642095a63883e83f49 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 2 20 1.1E-48 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CU254_RS07310 f875d1fac1ba42642095a63883e83f49 160 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 3 153 6.3E-58 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CU254_RS07310 f875d1fac1ba42642095a63883e83f49 160 Pfam PF01467 Cytidylyltransferase-like 6 132 1.9E-20 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CU254_RS07310 f875d1fac1ba42642095a63883e83f49 160 SUPERFAMILY SSF52374 1 153 3.49E-44 T 28-03-2018 CU254_RS07310 f875d1fac1ba42642095a63883e83f49 160 Gene3D G3DSA:3.40.50.620 1 156 7.8E-35 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS07310 f875d1fac1ba42642095a63883e83f49 160 ProDom PD016147 LIGASE LYASE CITRATE PRO-3S-LYASE SYNTHETASE TRANSFERASE CYTIDYLTRANSFERASE-RELATED:CITRATE ACETATE:SH-CITRATE CITC PLASMID 11 75 0.001 T 28-03-2018 CU254_RS07310 f875d1fac1ba42642095a63883e83f49 160 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 3 63 1.1E-18 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CU254_RS26225 55b0d31d6894a82631b508475b726a70 449 Pfam PF10117 McrBC 5-methylcytosine restriction system component 66 378 3.0E-25 T 28-03-2018 IPR019292 5-methylcytosine restriction system component CU254_RS23555 765e93807a532185f5566404c8ae622e 374 SUPERFAMILY SSF53223 4 147 1.22E-42 T 28-03-2018 CU254_RS23555 765e93807a532185f5566404c8ae622e 374 SMART SM00919 149 372 2.2E-99 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CU254_RS23555 765e93807a532185f5566404c8ae622e 374 SMART SM01274 4 137 1.4E-49 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CU254_RS23555 765e93807a532185f5566404c8ae622e 374 PIRSF PIRSF000106 99 374 1.6E-53 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CU254_RS23555 765e93807a532185f5566404c8ae622e 374 PIRSF PIRSF000106 29 104 1.3E-10 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CU254_RS23555 765e93807a532185f5566404c8ae622e 374 SUPERFAMILY SSF51735 149 371 3.01E-61 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS23555 765e93807a532185f5566404c8ae622e 374 Gene3D G3DSA:3.40.50.10380 1 146 1.2E-25 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CU254_RS23555 765e93807a532185f5566404c8ae622e 374 Gene3D G3DSA:3.40.50.720 147 374 8.5E-64 T 28-03-2018 CU254_RS23555 765e93807a532185f5566404c8ae622e 374 Pfam PF00390 Malic enzyme, N-terminal domain 19 96 1.8E-12 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CU254_RS23555 765e93807a532185f5566404c8ae622e 374 Pfam PF03949 Malic enzyme, NAD binding domain 151 354 2.1E-19 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CU254_RS37330 f99ef5688f1292c4fc528d98ace0f23f 321 TIGRFAM TIGR02960 SigX5: RNA polymerase sigma-70 factor, TIGR02960 family 2 316 7.3E-100 T 28-03-2018 IPR014305 RNA polymerase sigma-G type, actinobacteria CU254_RS37330 f99ef5688f1292c4fc528d98ace0f23f 321 SUPERFAMILY SSF88659 120 178 2.8E-12 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS37330 f99ef5688f1292c4fc528d98ace0f23f 321 Pfam PF08281 Sigma-70, region 4 123 174 9.3E-15 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS37330 f99ef5688f1292c4fc528d98ace0f23f 321 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 11 178 1.5E-20 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS37330 f99ef5688f1292c4fc528d98ace0f23f 321 Gene3D G3DSA:1.10.10.10 99 175 9.6E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS37330 f99ef5688f1292c4fc528d98ace0f23f 321 SUPERFAMILY SSF54427 192 306 1.07E-12 T 28-03-2018 IPR032710 NTF2-like domain CU254_RS37330 f99ef5688f1292c4fc528d98ace0f23f 321 Gene3D G3DSA:3.10.450.50 176 313 1.6E-15 T 28-03-2018 CU254_RS37330 f99ef5688f1292c4fc528d98ace0f23f 321 Pfam PF12680 SnoaL-like domain 198 282 4.3E-6 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CU254_RS37330 f99ef5688f1292c4fc528d98ace0f23f 321 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 29 60 - T 28-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS37330 f99ef5688f1292c4fc528d98ace0f23f 321 Pfam PF04542 Sigma-70 region 2 9 71 8.1E-19 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS37330 f99ef5688f1292c4fc528d98ace0f23f 321 Gene3D G3DSA:1.10.1740.10 2 76 1.5E-22 T 28-03-2018 CU254_RS37330 f99ef5688f1292c4fc528d98ace0f23f 321 SUPERFAMILY SSF88946 8 88 1.37E-21 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS03950 60e95dedf1956cd2f3c32ded2c3af613 76 Pfam PF11305 Protein of unknown function (DUF3107) 1 73 3.3E-29 T 28-03-2018 IPR021456 Protein of unknown function DUF3107 CU254_RS19515 394bf5ba2a21eab10961653d77c97539 434 SUPERFAMILY SSF55031 283 321 4.08E-11 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CU254_RS19515 394bf5ba2a21eab10961653d77c97539 434 SUPERFAMILY SSF55031 194 233 4.08E-11 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CU254_RS19515 394bf5ba2a21eab10961653d77c97539 434 Gene3D G3DSA:3.40.630.10 2 197 5.2E-40 T 28-03-2018 CU254_RS19515 394bf5ba2a21eab10961653d77c97539 434 SUPERFAMILY SSF53187 344 432 1.31E-54 T 28-03-2018 CU254_RS19515 394bf5ba2a21eab10961653d77c97539 434 SUPERFAMILY SSF53187 5 183 1.31E-54 T 28-03-2018 CU254_RS19515 394bf5ba2a21eab10961653d77c97539 434 Gene3D G3DSA:3.40.630.10 318 434 5.4E-9 T 28-03-2018 CU254_RS19515 394bf5ba2a21eab10961653d77c97539 434 Gene3D G3DSA:3.30.70.360 198 317 3.3E-20 T 28-03-2018 CU254_RS19515 394bf5ba2a21eab10961653d77c97539 434 Pfam PF01546 Peptidase family M20/M25/M40 74 432 1.3E-34 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CU254_RS19515 394bf5ba2a21eab10961653d77c97539 434 Pfam PF07687 Peptidase dimerisation domain 191 318 3.7E-14 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CU254_RS06825 346558ddddfef48983f26e7388a43a3b 402 Gene3D G3DSA:2.120.10.30 66 388 5.0E-24 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CU254_RS06825 346558ddddfef48983f26e7388a43a3b 402 Pfam PF07995 Glucose / Sorbosone dehydrogenase 111 289 4.2E-21 T 28-03-2018 IPR012938 Glucose/Sorbosone dehydrogenase CU254_RS06825 346558ddddfef48983f26e7388a43a3b 402 SUPERFAMILY SSF63829 116 302 1.54E-11 T 28-03-2018 CU254_RS24340 bf8106f828630de5b1be2dd43b55e559 293 Pfam PF07728 AAA domain (dynein-related subfamily) 41 190 1.1E-10 T 28-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 CU254_RS24340 bf8106f828630de5b1be2dd43b55e559 293 Gene3D G3DSA:3.40.50.300 11 234 1.7E-29 T 28-03-2018 CU254_RS24340 bf8106f828630de5b1be2dd43b55e559 293 SUPERFAMILY SSF52540 110 276 2.54E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS24340 bf8106f828630de5b1be2dd43b55e559 293 SUPERFAMILY SSF52540 35 83 2.54E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS24340 bf8106f828630de5b1be2dd43b55e559 293 SMART SM00382 37 201 1.9E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS12580 566acf6cba5b08b77cd8ca8dccb0bc03 224 SUPERFAMILY SSF48008 93 223 4.71E-25 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS12580 566acf6cba5b08b77cd8ca8dccb0bc03 224 SUPERFAMILY SSF46785 6 78 1.48E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS12580 566acf6cba5b08b77cd8ca8dccb0bc03 224 Gene3D G3DSA:1.10.10.10 3 76 6.1E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS12580 566acf6cba5b08b77cd8ca8dccb0bc03 224 SMART SM00345 15 74 1.2E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS12580 566acf6cba5b08b77cd8ca8dccb0bc03 224 Gene3D G3DSA:1.20.120.530 84 224 5.5E-29 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS12580 566acf6cba5b08b77cd8ca8dccb0bc03 224 SMART SM00895 94 218 3.4E-23 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS12580 566acf6cba5b08b77cd8ca8dccb0bc03 224 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 74 1.3E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS12580 566acf6cba5b08b77cd8ca8dccb0bc03 224 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 6.4E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS12580 566acf6cba5b08b77cd8ca8dccb0bc03 224 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 6.4E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS12580 566acf6cba5b08b77cd8ca8dccb0bc03 224 Pfam PF07729 FCD domain 94 217 9.8E-24 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS34585 39c1b9cae411fb1ba866d891d4013d99 783 Gene3D G3DSA:3.50.50.60 1 382 9.2E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS34585 39c1b9cae411fb1ba866d891d4013d99 783 Pfam PF01494 FAD binding domain 128 326 3.0E-14 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CU254_RS34585 39c1b9cae411fb1ba866d891d4013d99 783 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 267 282 4.8E-13 T 28-03-2018 CU254_RS34585 39c1b9cae411fb1ba866d891d4013d99 783 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 129 144 4.8E-13 T 28-03-2018 CU254_RS34585 39c1b9cae411fb1ba866d891d4013d99 783 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 4.8E-13 T 28-03-2018 CU254_RS34585 39c1b9cae411fb1ba866d891d4013d99 783 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 315 331 4.8E-13 T 28-03-2018 CU254_RS34585 39c1b9cae411fb1ba866d891d4013d99 783 SUPERFAMILY SSF51395 392 739 2.3E-113 T 28-03-2018 CU254_RS34585 39c1b9cae411fb1ba866d891d4013d99 783 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 394 729 7.1E-64 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CU254_RS34585 39c1b9cae411fb1ba866d891d4013d99 783 SUPERFAMILY SSF51905 254 343 1.94E-44 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS34585 39c1b9cae411fb1ba866d891d4013d99 783 SUPERFAMILY SSF51905 3 150 1.94E-44 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS34585 39c1b9cae411fb1ba866d891d4013d99 783 Gene3D G3DSA:3.20.20.70 383 760 1.2E-116 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS18490 121978ec4ea1969fc30a4f8213cbdb0c 507 Gene3D G3DSA:3.40.190.10 152 288 1.4E-18 T 28-03-2018 CU254_RS18490 121978ec4ea1969fc30a4f8213cbdb0c 507 PIRSF PIRSF002741 2 497 3.1E-52 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CU254_RS18490 121978ec4ea1969fc30a4f8213cbdb0c 507 SUPERFAMILY SSF53850 29 498 8.14E-80 T 28-03-2018 CU254_RS18490 121978ec4ea1969fc30a4f8213cbdb0c 507 Gene3D G3DSA:3.10.105.10 289 476 7.3E-27 T 28-03-2018 CU254_RS18490 121978ec4ea1969fc30a4f8213cbdb0c 507 Gene3D G3DSA:3.90.76.10 60 151 2.9E-22 T 28-03-2018 CU254_RS18490 121978ec4ea1969fc30a4f8213cbdb0c 507 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 78 425 1.6E-53 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CU254_RS25025 bfca34bad71bc7d81d5c921801c4937f 277 Gene3D G3DSA:3.40.50.720 9 276 3.5E-68 T 28-03-2018 CU254_RS25025 bfca34bad71bc7d81d5c921801c4937f 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 111 122 3.1E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS25025 bfca34bad71bc7d81d5c921801c4937f 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 238 258 3.1E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS25025 bfca34bad71bc7d81d5c921801c4937f 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 201 3.1E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS25025 bfca34bad71bc7d81d5c921801c4937f 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 28 45 3.1E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS25025 bfca34bad71bc7d81d5c921801c4937f 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 203 220 3.1E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS25025 bfca34bad71bc7d81d5c921801c4937f 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 172 3.1E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS25025 bfca34bad71bc7d81d5c921801c4937f 277 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 182 201 1.1E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS25025 bfca34bad71bc7d81d5c921801c4937f 277 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 111 122 1.1E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS25025 bfca34bad71bc7d81d5c921801c4937f 277 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 162 170 1.1E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS25025 bfca34bad71bc7d81d5c921801c4937f 277 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 27 213 0.0054 T 28-03-2018 CU254_RS25025 bfca34bad71bc7d81d5c921801c4937f 277 SUPERFAMILY SSF51735 23 274 1.93E-76 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS25025 bfca34bad71bc7d81d5c921801c4937f 277 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 169 197 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS25025 bfca34bad71bc7d81d5c921801c4937f 277 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 33 273 5.2E-63 T 28-03-2018 CU254_RS36215 3ba4049c235e1fd7d95f61f840564a63 329 Gene3D G3DSA:3.90.1200.10 63 325 1.2E-10 T 28-03-2018 CU254_RS36215 3ba4049c235e1fd7d95f61f840564a63 329 SUPERFAMILY SSF56112 161 231 9.84E-10 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS28620 31393cd9dad748b2828dbc562ce443e0 199 Pfam PF16708 Lipoprotein confined to pathogenic Mycobacterium 41 185 1.8E-23 T 28-03-2018 IPR032018 Putative lipoprotein, pathogenic bacteria CU254_RS13270 6a9e273f0038e990297a1b9b3ff11051 1820 Gene3D G3DSA:2.40.50.100 579 637 1.7E-11 T 28-03-2018 CU254_RS13270 6a9e273f0038e990297a1b9b3ff11051 1820 Gene3D G3DSA:3.30.1490.20 129 214 2.1E-20 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CU254_RS13270 6a9e273f0038e990297a1b9b3ff11051 1820 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 115 2.3E-33 T 28-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CU254_RS13270 6a9e273f0038e990297a1b9b3ff11051 1820 Gene3D G3DSA:3.90.226.10 1507 1820 1.2E-38 T 28-03-2018 CU254_RS13270 6a9e273f0038e990297a1b9b3ff11051 1820 Pfam PF02785 Biotin carboxylase C-terminal domain 339 448 4.2E-35 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CU254_RS13270 6a9e273f0038e990297a1b9b3ff11051 1820 Gene3D G3DSA:3.40.50.20 1 128 2.0E-39 T 28-03-2018 CU254_RS13270 6a9e273f0038e990297a1b9b3ff11051 1820 Pfam PF00364 Biotin-requiring enzyme 587 652 2.2E-8 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CU254_RS13270 6a9e273f0038e990297a1b9b3ff11051 1820 SMART SM00878 339 447 3.7E-51 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CU254_RS13270 6a9e273f0038e990297a1b9b3ff11051 1820 Gene3D G3DSA:2.40.50.100 638 1050 0.064 T 28-03-2018 CU254_RS13270 6a9e273f0038e990297a1b9b3ff11051 1820 Gene3D G3DSA:3.90.226.10 1250 1497 2.7E-12 T 28-03-2018 CU254_RS13270 6a9e273f0038e990297a1b9b3ff11051 1820 SUPERFAMILY SSF56059 88 332 3.36E-58 T 28-03-2018 CU254_RS13270 6a9e273f0038e990297a1b9b3ff11051 1820 SUPERFAMILY SSF51246 334 449 1.15E-35 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CU254_RS13270 6a9e273f0038e990297a1b9b3ff11051 1820 Gene3D G3DSA:3.30.470.20 215 449 2.4E-84 T 28-03-2018 CU254_RS13270 6a9e273f0038e990297a1b9b3ff11051 1820 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 120 327 1.7E-57 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CU254_RS13270 6a9e273f0038e990297a1b9b3ff11051 1820 SUPERFAMILY SSF52096 1262 1492 7.82E-22 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS13270 6a9e273f0038e990297a1b9b3ff11051 1820 Pfam PF01039 Carboxyl transferase domain 1325 1815 3.0E-29 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 CU254_RS13270 6a9e273f0038e990297a1b9b3ff11051 1820 SUPERFAMILY SSF52440 2 118 1.25E-32 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CU254_RS13270 6a9e273f0038e990297a1b9b3ff11051 1820 SUPERFAMILY SSF51230 578 653 4.58E-14 T 28-03-2018 IPR011053 Single hybrid motif CU254_RS13270 6a9e273f0038e990297a1b9b3ff11051 1820 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 158 172 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CU254_RS13270 6a9e273f0038e990297a1b9b3ff11051 1820 SUPERFAMILY SSF52096 1542 1816 1.89E-35 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS13270 6a9e273f0038e990297a1b9b3ff11051 1820 Pfam PF08326 Acetyl-CoA carboxylase, central region 1011 1199 3.1E-17 T 28-03-2018 IPR013537 Acetyl-CoA carboxylase, central domain GO:0003989|GO:0005524|GO:0006633 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-163765|Reactome: R-HSA-196780|Reactome: R-HSA-200425|Reactome: R-HSA-2426168 CU254_RS13270 6a9e273f0038e990297a1b9b3ff11051 1820 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 291 298 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CU254_RS07375 318ed852416df9d1551040c0dcf5b472 454 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 228 235 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CU254_RS07375 318ed852416df9d1551040c0dcf5b472 454 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 256 267 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CU254_RS07375 318ed852416df9d1551040c0dcf5b472 454 SUPERFAMILY SSF53720 3 449 3.53E-155 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CU254_RS07375 318ed852416df9d1551040c0dcf5b472 454 Gene3D G3DSA:3.40.605.10 1 243 7.2E-94 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CU254_RS07375 318ed852416df9d1551040c0dcf5b472 454 Pfam PF00171 Aldehyde dehydrogenase family 3 448 1.2E-158 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CU254_RS07375 318ed852416df9d1551040c0dcf5b472 454 Gene3D G3DSA:3.40.309.10 244 434 2.4E-64 T 28-03-2018 CU254_RS21230 8c773a94fc6d0b6000b51472cd8e4a7f 191 SUPERFAMILY SSF48498 87 188 1.72E-8 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS21230 8c773a94fc6d0b6000b51472cd8e4a7f 191 Gene3D G3DSA:1.10.357.10 69 190 1.2E-11 T 28-03-2018 CU254_RS21230 8c773a94fc6d0b6000b51472cd8e4a7f 191 Gene3D G3DSA:1.10.10.60 6 44 4.7E-14 T 28-03-2018 CU254_RS21230 8c773a94fc6d0b6000b51472cd8e4a7f 191 Gene3D G3DSA:1.10.260.40 45 68 3.6E-10 T 28-03-2018 CU254_RS21230 8c773a94fc6d0b6000b51472cd8e4a7f 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 8.2E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS21230 8c773a94fc6d0b6000b51472cd8e4a7f 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 8.2E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS21230 8c773a94fc6d0b6000b51472cd8e4a7f 191 SUPERFAMILY SSF46689 8 90 1.85E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS21230 8c773a94fc6d0b6000b51472cd8e4a7f 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 66 1.0E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS15280 d8db7918243b04aa139670421b87bca0 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 6.6E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS15280 d8db7918243b04aa139670421b87bca0 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 6.6E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS15280 d8db7918243b04aa139670421b87bca0 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 202 222 6.6E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS15280 d8db7918243b04aa139670421b87bca0 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 6.6E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS15280 d8db7918243b04aa139670421b87bca0 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 6.6E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS15280 d8db7918243b04aa139670421b87bca0 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 6.6E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS15280 d8db7918243b04aa139670421b87bca0 242 Gene3D G3DSA:3.40.50.720 7 153 1.1E-28 T 28-03-2018 CU254_RS15280 d8db7918243b04aa139670421b87bca0 242 SUPERFAMILY SSF51735 11 240 2.82E-55 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS15280 d8db7918243b04aa139670421b87bca0 242 Gene3D G3DSA:3.40.50.720 154 240 4.0E-21 T 28-03-2018 CU254_RS15280 d8db7918243b04aa139670421b87bca0 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 9.5E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS15280 d8db7918243b04aa139670421b87bca0 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 128 136 9.5E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS15280 d8db7918243b04aa139670421b87bca0 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 9.5E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS15280 d8db7918243b04aa139670421b87bca0 242 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 239 2.6E-41 T 28-03-2018 CU254_RS34770 12145392ff893fe6b541dc1e37ed2a88 214 Gene3D G3DSA:1.10.10.60 27 66 7.1E-13 T 28-03-2018 CU254_RS34770 12145392ff893fe6b541dc1e37ed2a88 214 Gene3D G3DSA:1.10.10.60 67 89 3.8E-8 T 28-03-2018 CU254_RS34770 12145392ff893fe6b541dc1e37ed2a88 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 33 77 1.5E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS34770 12145392ff893fe6b541dc1e37ed2a88 214 Gene3D G3DSA:1.10.357.10 90 214 3.5E-8 T 28-03-2018 CU254_RS34770 12145392ff893fe6b541dc1e37ed2a88 214 SUPERFAMILY SSF46689 27 94 4.24E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS35555 b886ba307cb083fa7cc2a8e80619aa4e 249 Gene3D G3DSA:1.10.10.10 7 85 1.6E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS35555 b886ba307cb083fa7cc2a8e80619aa4e 249 SUPERFAMILY SSF46785 17 91 3.13E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS35555 b886ba307cb083fa7cc2a8e80619aa4e 249 Pfam PF00392 Bacterial regulatory proteins, gntR family 26 81 1.1E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS35555 b886ba307cb083fa7cc2a8e80619aa4e 249 SMART SM00345 25 82 8.6E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS35555 b886ba307cb083fa7cc2a8e80619aa4e 249 SUPERFAMILY SSF64288 70 246 2.36E-53 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CU254_RS35555 b886ba307cb083fa7cc2a8e80619aa4e 249 SMART SM00866 102 242 5.0E-46 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CU254_RS35555 b886ba307cb083fa7cc2a8e80619aa4e 249 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 56 3.1E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS35555 b886ba307cb083fa7cc2a8e80619aa4e 249 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 56 72 3.1E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS35555 b886ba307cb083fa7cc2a8e80619aa4e 249 Gene3D G3DSA:3.40.1410.10 86 248 6.2E-49 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CU254_RS35555 b886ba307cb083fa7cc2a8e80619aa4e 249 Pfam PF07702 UTRA domain 103 242 1.9E-44 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CU254_RS13660 0a916b73ee5603c8831e0da063517fda 378 Gene3D G3DSA:1.10.630.10 186 377 9.7E-38 T 28-03-2018 CU254_RS13660 0a916b73ee5603c8831e0da063517fda 378 Gene3D G3DSA:1.10.630.10 2 185 1.7E-23 T 28-03-2018 CU254_RS13660 0a916b73ee5603c8831e0da063517fda 378 SUPERFAMILY SSF48264 7 366 2.1E-76 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS13660 0a916b73ee5603c8831e0da063517fda 378 PRINTS PR00359 B-class P450 signature 86 97 2.3E-43 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS13660 0a916b73ee5603c8831e0da063517fda 378 PRINTS PR00359 B-class P450 signature 331 342 2.3E-43 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS13660 0a916b73ee5603c8831e0da063517fda 378 PRINTS PR00359 B-class P450 signature 132 148 2.3E-43 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS13660 0a916b73ee5603c8831e0da063517fda 378 PRINTS PR00359 B-class P450 signature 273 300 2.3E-43 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS13660 0a916b73ee5603c8831e0da063517fda 378 PRINTS PR00359 B-class P450 signature 255 266 2.3E-43 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS13660 0a916b73ee5603c8831e0da063517fda 378 PRINTS PR00359 B-class P450 signature 322 331 2.3E-43 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS13660 0a916b73ee5603c8831e0da063517fda 378 PRINTS PR00359 B-class P450 signature 149 164 2.3E-43 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS13660 0a916b73ee5603c8831e0da063517fda 378 PRINTS PR00359 B-class P450 signature 301 316 2.3E-43 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS13660 0a916b73ee5603c8831e0da063517fda 378 Pfam PF00067 Cytochrome P450 252 352 4.0E-17 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS20125 3ecf4c31f055adcc47e9a9f30a00a163 226 Gene3D G3DSA:1.10.10.10 174 219 2.2E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS20125 3ecf4c31f055adcc47e9a9f30a00a163 226 SMART SM01012 162 217 4.1E-22 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 CU254_RS20125 3ecf4c31f055adcc47e9a9f30a00a163 226 PIRSF PIRSF036625 1 226 2.5E-53 T 28-03-2018 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative CU254_RS20125 3ecf4c31f055adcc47e9a9f30a00a163 226 Pfam PF13185 GAF domain 6 150 2.0E-8 T 28-03-2018 IPR003018 GAF domain GO:0005515 CU254_RS20125 3ecf4c31f055adcc47e9a9f30a00a163 226 SUPERFAMILY SSF52172 142 216 4.08E-11 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS20125 3ecf4c31f055adcc47e9a9f30a00a163 226 Pfam PF03861 ANTAR domain 165 215 5.2E-21 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 CU254_RS20125 3ecf4c31f055adcc47e9a9f30a00a163 226 Gene3D G3DSA:3.30.450.40 1 173 2.5E-21 T 28-03-2018 IPR029016 GAF domain-like CU254_RS20125 3ecf4c31f055adcc47e9a9f30a00a163 226 SUPERFAMILY SSF55781 10 165 3.05E-16 T 28-03-2018 IPR029016 GAF domain-like CU254_RS25365 d9a21359d90f1666b7d7628a315b64d4 429 Pfam PF01546 Peptidase family M20/M25/M40 72 427 3.8E-31 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CU254_RS25365 d9a21359d90f1666b7d7628a315b64d4 429 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 71 80 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CU254_RS25365 d9a21359d90f1666b7d7628a315b64d4 429 Gene3D G3DSA:3.30.70.360 196 331 1.6E-22 T 28-03-2018 CU254_RS25365 d9a21359d90f1666b7d7628a315b64d4 429 Pfam PF07687 Peptidase dimerisation domain 190 318 1.2E-13 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CU254_RS25365 d9a21359d90f1666b7d7628a315b64d4 429 Gene3D G3DSA:3.40.630.10 1 195 1.2E-43 T 28-03-2018 CU254_RS25365 d9a21359d90f1666b7d7628a315b64d4 429 SUPERFAMILY SSF55031 278 317 1.31E-10 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CU254_RS25365 d9a21359d90f1666b7d7628a315b64d4 429 SUPERFAMILY SSF55031 192 231 1.31E-10 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CU254_RS25365 d9a21359d90f1666b7d7628a315b64d4 429 SUPERFAMILY SSF53187 339 427 6.0E-51 T 28-03-2018 CU254_RS25365 d9a21359d90f1666b7d7628a315b64d4 429 SUPERFAMILY SSF53187 5 183 6.0E-51 T 28-03-2018 CU254_RS22280 23257cb4d05a2a15a0e3a79febf3ecb2 250 SMART SM00363 10 67 9.3E-11 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CU254_RS22280 23257cb4d05a2a15a0e3a79febf3ecb2 250 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 112 126 - T 28-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 CU254_RS22280 23257cb4d05a2a15a0e3a79febf3ecb2 250 Pfam PF00849 RNA pseudouridylate synthase 72 207 3.2E-17 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CU254_RS22280 23257cb4d05a2a15a0e3a79febf3ecb2 250 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 76 237 5.0E-38 T 28-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 CU254_RS22280 23257cb4d05a2a15a0e3a79febf3ecb2 250 SUPERFAMILY SSF55174 7 67 2.16E-14 T 28-03-2018 CU254_RS22280 23257cb4d05a2a15a0e3a79febf3ecb2 250 SUPERFAMILY SSF55120 56 248 9.18E-42 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CU254_RS22280 23257cb4d05a2a15a0e3a79febf3ecb2 250 Pfam PF01479 S4 domain 11 54 1.1E-13 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CU254_RS22280 23257cb4d05a2a15a0e3a79febf3ecb2 250 Gene3D G3DSA:3.10.290.10 4 66 1.5E-17 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CU254_RS22280 23257cb4d05a2a15a0e3a79febf3ecb2 250 Gene3D G3DSA:3.30.2350.10 67 249 7.6E-36 T 28-03-2018 CU254_RS25560 0b014cb2df4913c9c23f4e3cf9a61f9c 313 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 34 96 3.7E-8 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CU254_RS25560 0b014cb2df4913c9c23f4e3cf9a61f9c 313 Gene3D G3DSA:3.90.180.10 163 313 1.1E-13 T 28-03-2018 CU254_RS25560 0b014cb2df4913c9c23f4e3cf9a61f9c 313 Gene3D G3DSA:3.90.180.10 1 162 4.1E-43 T 28-03-2018 CU254_RS25560 0b014cb2df4913c9c23f4e3cf9a61f9c 313 SMART SM00829 16 311 7.4E-13 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CU254_RS25560 0b014cb2df4913c9c23f4e3cf9a61f9c 313 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 155 176 - T 28-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 CU254_RS25560 0b014cb2df4913c9c23f4e3cf9a61f9c 313 SUPERFAMILY SSF51735 128 251 2.29E-24 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS25560 0b014cb2df4913c9c23f4e3cf9a61f9c 313 Pfam PF00107 Zinc-binding dehydrogenase 166 251 2.8E-10 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CU254_RS25560 0b014cb2df4913c9c23f4e3cf9a61f9c 313 SUPERFAMILY SSF50129 5 160 6.24E-31 T 28-03-2018 IPR011032 GroES-like CU254_RS36695 e23b6918cf376030665749310e7f8184 483 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 266 283 3.1E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS36695 e23b6918cf376030665749310e7f8184 483 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 383 399 3.1E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS36695 e23b6918cf376030665749310e7f8184 483 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 336 347 3.1E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS36695 e23b6918cf376030665749310e7f8184 483 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 409 428 3.1E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS36695 e23b6918cf376030665749310e7f8184 483 SUPERFAMILY SSF51735 263 462 1.51E-25 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS36695 e23b6918cf376030665749310e7f8184 483 Gene3D G3DSA:3.40.50.720 258 479 7.2E-26 T 28-03-2018 CU254_RS36695 e23b6918cf376030665749310e7f8184 483 Gene3D G3DSA:3.10.129.10 1 241 2.0E-30 T 28-03-2018 CU254_RS36695 e23b6918cf376030665749310e7f8184 483 Pfam PF00106 short chain dehydrogenase 266 443 2.9E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS36695 e23b6918cf376030665749310e7f8184 483 Pfam PF01575 MaoC like domain 3 47 4.0E-13 T 28-03-2018 IPR002539 MaoC-like domain CU254_RS36695 e23b6918cf376030665749310e7f8184 483 SUPERFAMILY SSF54637 5 81 5.06E-16 T 28-03-2018 IPR029069 HotDog domain CU254_RS18010 4f013a6d8d388b752461816eb1ef9126 317 Pfam PF01882 Protein of unknown function DUF58 56 140 4.1E-17 T 28-03-2018 IPR002881 Domain of unknown function DUF58 CU254_RS18010 4f013a6d8d388b752461816eb1ef9126 317 Gene3D G3DSA:3.40.50.410 68 290 1.5E-16 T 28-03-2018 IPR002035 von Willebrand factor, type A CU254_RS35965 d7248674b7abe38f40da693577befcdb 226 Gene3D G3DSA:2.60.40.10 56 173 0.21 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS35965 d7248674b7abe38f40da693577befcdb 226 Gene3D G3DSA:2.60.40.10 185 219 0.4 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS35965 d7248674b7abe38f40da693577befcdb 226 SUPERFAMILY SSF110087 185 222 3.4E-6 T 28-03-2018 IPR007410 Copper chaperone PCuAC CU254_RS03195 fe3e4562b326983c1e4f5c55590b24d4 177 Gene3D G3DSA:3.40.630.30 1 171 1.2E-21 T 28-03-2018 CU254_RS03195 fe3e4562b326983c1e4f5c55590b24d4 177 SUPERFAMILY SSF55729 13 158 4.58E-30 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS03195 fe3e4562b326983c1e4f5c55590b24d4 177 Pfam PF13302 Acetyltransferase (GNAT) domain 22 153 6.0E-22 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS24515 6ea06b6dab304fb93fd870a59cf3ff8a 438 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 8 314 2.3E-126 T 28-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 CU254_RS24515 6ea06b6dab304fb93fd870a59cf3ff8a 438 SMART SM00865 204 321 2.8E-55 T 28-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 CU254_RS24515 6ea06b6dab304fb93fd870a59cf3ff8a 438 Pfam PF12327 FtsZ family, C-terminal domain 219 313 2.6E-35 T 28-03-2018 IPR024757 Cell division protein FtsZ, C-terminal CU254_RS24515 6ea06b6dab304fb93fd870a59cf3ff8a 438 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 11 169 9.5E-39 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CU254_RS24515 6ea06b6dab304fb93fd870a59cf3ff8a 438 ProSitePatterns PS01135 FtsZ protein signature 2. 94 115 - T 28-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 CU254_RS24515 6ea06b6dab304fb93fd870a59cf3ff8a 438 SMART SM00864 10 202 2.8E-107 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CU254_RS24515 6ea06b6dab304fb93fd870a59cf3ff8a 438 Gene3D G3DSA:3.40.50.1440 5 211 2.1E-38 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CU254_RS24515 6ea06b6dab304fb93fd870a59cf3ff8a 438 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 6 328 38.302 T 28-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 CU254_RS24515 6ea06b6dab304fb93fd870a59cf3ff8a 438 SUPERFAMILY SSF55307 201 315 1.53E-43 T 28-03-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 CU254_RS24515 6ea06b6dab304fb93fd870a59cf3ff8a 438 SUPERFAMILY SSF52490 9 205 1.31E-65 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CU254_RS24515 6ea06b6dab304fb93fd870a59cf3ff8a 438 ProSitePatterns PS01134 FtsZ protein signature 1. 41 75 - T 28-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 CU254_RS24515 6ea06b6dab304fb93fd870a59cf3ff8a 438 PRINTS PR00423 Cell division protein FtsZ signature 95 115 1.1E-50 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CU254_RS24515 6ea06b6dab304fb93fd870a59cf3ff8a 438 PRINTS PR00423 Cell division protein FtsZ signature 123 144 1.1E-50 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CU254_RS24515 6ea06b6dab304fb93fd870a59cf3ff8a 438 PRINTS PR00423 Cell division protein FtsZ signature 209 230 1.1E-50 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CU254_RS24515 6ea06b6dab304fb93fd870a59cf3ff8a 438 PRINTS PR00423 Cell division protein FtsZ signature 186 208 1.1E-50 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CU254_RS24515 6ea06b6dab304fb93fd870a59cf3ff8a 438 Gene3D G3DSA:3.30.1330.20 212 320 5.0E-46 T 28-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 CU254_RS23705 0a66d02c4fd641f5cb4a599aaaff0a11 824 Pfam PF00550 Phosphopantetheine attachment site 754 816 2.0E-6 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS23705 0a66d02c4fd641f5cb4a599aaaff0a11 824 SUPERFAMILY SSF52777 9 209 1.22E-17 T 28-03-2018 CU254_RS23705 0a66d02c4fd641f5cb4a599aaaff0a11 824 Gene3D G3DSA:3.30.300.30 640 758 3.7E-37 T 28-03-2018 CU254_RS23705 0a66d02c4fd641f5cb4a599aaaff0a11 824 Gene3D G3DSA:3.40.50.980 374 558 9.7E-44 T 28-03-2018 CU254_RS23705 0a66d02c4fd641f5cb4a599aaaff0a11 824 SMART SM00823 Phosphopantetheine attachment site 753 820 0.0091 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS23705 0a66d02c4fd641f5cb4a599aaaff0a11 824 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 263 669 9.5E-121 T 28-03-2018 IPR010071 Amino acid adenylation domain CU254_RS23705 0a66d02c4fd641f5cb4a599aaaff0a11 824 SUPERFAMILY SSF47336 745 817 1.28E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS23705 0a66d02c4fd641f5cb4a599aaaff0a11 824 ProSitePatterns PS00455 Putative AMP-binding domain signature. 387 398 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS23705 0a66d02c4fd641f5cb4a599aaaff0a11 824 Gene3D G3DSA:3.40.50.980 234 373 1.0E-37 T 28-03-2018 CU254_RS23705 0a66d02c4fd641f5cb4a599aaaff0a11 824 SUPERFAMILY SSF56801 223 766 4.32E-152 T 28-03-2018 CU254_RS23705 0a66d02c4fd641f5cb4a599aaaff0a11 824 Pfam PF00501 AMP-binding enzyme 242 645 2.0E-94 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS23705 0a66d02c4fd641f5cb4a599aaaff0a11 824 Pfam PF13193 AMP-binding enzyme C-terminal domain 653 725 1.8E-10 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS23705 0a66d02c4fd641f5cb4a599aaaff0a11 824 Gene3D G3DSA:1.10.1200.10 759 824 6.0E-15 T 28-03-2018 CU254_RS23705 0a66d02c4fd641f5cb4a599aaaff0a11 824 Gene3D G3DSA:2.30.38.10 559 635 1.1E-23 T 28-03-2018 CU254_RS23605 a4267b4b14f889a378e91fba4f9c7dc2 427 Pfam PF12390 Selenocysteine synthase N terminal 5 44 2.6E-9 T 28-03-2018 IPR025862 L-seryl-tRNA selenium transferase N-terminal domain KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 CU254_RS23605 a4267b4b14f889a378e91fba4f9c7dc2 427 Gene3D G3DSA:3.40.640.10 30 326 2.8E-26 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS23605 a4267b4b14f889a378e91fba4f9c7dc2 427 SUPERFAMILY SSF53383 67 350 1.45E-31 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS23605 a4267b4b14f889a378e91fba4f9c7dc2 427 Hamap MF_00423 L-seryl-tRNA(Sec) selenium transferase [selA]. 1 427 177.068 T 28-03-2018 IPR004534 L-seryl-tRNA(Sec) selenium transferase GO:0001514|GO:0004125|GO:0005737 KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 CU254_RS23605 a4267b4b14f889a378e91fba4f9c7dc2 427 Pfam PF03841 L-seryl-tRNA selenium transferase 71 411 7.3E-100 T 28-03-2018 IPR018319 L-seryl-tRNA selenium transferase-like KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 CU254_RS23605 a4267b4b14f889a378e91fba4f9c7dc2 427 TIGRFAM TIGR00474 selA: L-seryl-tRNA(Sec) selenium transferase 6 424 9.3E-129 T 28-03-2018 IPR004534 L-seryl-tRNA(Sec) selenium transferase GO:0001514|GO:0004125|GO:0005737 KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 CU254_RS03625 ba76189feb9a749631303636737a4e07 326 Hamap MF_02122 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 10 324 42.769 T 28-03-2018 IPR026586 Type 2 tetrahydrodipicolinate N-succinyltransferase family GO:0008666 KEGG: 00300+2.3.1.117 CU254_RS03625 ba76189feb9a749631303636737a4e07 326 Gene3D G3DSA:3.30.60.70 121 160 2.9E-20 T 28-03-2018 CU254_RS03625 ba76189feb9a749631303636737a4e07 326 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 242 274 7.9E-13 T 28-03-2018 IPR001451 Hexapeptide repeat CU254_RS03625 ba76189feb9a749631303636737a4e07 326 Gene3D G3DSA:2.160.10.10 161 305 1.9E-15 T 28-03-2018 CU254_RS03625 ba76189feb9a749631303636737a4e07 326 TIGRFAM TIGR03535 DapD_actino: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 12 326 3.4E-152 T 28-03-2018 IPR019875 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, actinobacteria KEGG: 00300+2.3.1.117 CU254_RS03625 ba76189feb9a749631303636737a4e07 326 SUPERFAMILY SSF51161 91 305 1.29E-35 T 28-03-2018 IPR011004 Trimeric LpxA-like CU254_RS03625 ba76189feb9a749631303636737a4e07 326 Pfam PF14789 Tetrahydrodipicolinate N-succinyltransferase middle 121 160 3.0E-19 T 28-03-2018 IPR032784 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, middle domain KEGG: 00300+2.3.1.117 CU254_RS33120 b7381286c7448a8c7a8ba6adb70bf55a 197 Gene3D G3DSA:1.10.10.10 95 197 1.5E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS33120 b7381286c7448a8c7a8ba6adb70bf55a 197 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 137 151 4.2E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS33120 b7381286c7448a8c7a8ba6adb70bf55a 197 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 167 4.2E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS33120 b7381286c7448a8c7a8ba6adb70bf55a 197 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 179 4.2E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS33120 b7381286c7448a8c7a8ba6adb70bf55a 197 SMART SM00421 134 191 2.7E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS33120 b7381286c7448a8c7a8ba6adb70bf55a 197 SUPERFAMILY SSF46894 129 197 4.08E-18 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS33120 b7381286c7448a8c7a8ba6adb70bf55a 197 Pfam PF00196 Bacterial regulatory proteins, luxR family 136 191 4.6E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS27580 ef607a17bd6cec736fddd0b8f96ad3db 1659 PIRSF PIRSF036761 15 1659 0.0 T 28-03-2018 IPR007780 NAD-glutamate dehydrogenase, bacteria GO:0004352|GO:0019551 CU254_RS27580 ef607a17bd6cec736fddd0b8f96ad3db 1659 Pfam PF05088 Bacterial NAD-glutamate dehydrogenase 89 1655 0.0 T 28-03-2018 IPR028971 NAD-glutamate dehydrogenase GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 CU254_RS27580 ef607a17bd6cec736fddd0b8f96ad3db 1659 SUPERFAMILY SSF51735 989 1091 4.53E-25 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS27580 ef607a17bd6cec736fddd0b8f96ad3db 1659 SUPERFAMILY SSF51735 1129 1259 4.53E-25 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS27580 ef607a17bd6cec736fddd0b8f96ad3db 1659 Gene3D G3DSA:3.40.50.720 982 1311 1.0E-48 T 28-03-2018 CU254_RS27580 ef607a17bd6cec736fddd0b8f96ad3db 1659 SUPERFAMILY SSF53223 804 1000 6.33E-23 T 28-03-2018 CU254_RS25130 7d49a3ba405e03c8babdc3f0f413ea07 381 SUPERFAMILY SSF88659 304 378 1.25E-14 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS25130 7d49a3ba405e03c8babdc3f0f413ea07 381 SUPERFAMILY SSF88659 87 145 3.97E-9 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS25130 7d49a3ba405e03c8babdc3f0f413ea07 381 Pfam PF08281 Sigma-70, region 4 322 372 2.7E-9 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS25130 7d49a3ba405e03c8babdc3f0f413ea07 381 Pfam PF08281 Sigma-70, region 4 94 141 1.6E-10 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS25130 7d49a3ba405e03c8babdc3f0f413ea07 381 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 215 376 5.2E-25 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS25130 7d49a3ba405e03c8babdc3f0f413ea07 381 Pfam PF04542 Sigma-70 region 2 219 290 4.2E-12 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS25130 7d49a3ba405e03c8babdc3f0f413ea07 381 SUPERFAMILY SSF88946 205 308 2.94E-16 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS25130 7d49a3ba405e03c8babdc3f0f413ea07 381 SMART SM00421 96 157 0.0064 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS25130 7d49a3ba405e03c8babdc3f0f413ea07 381 Gene3D G3DSA:1.10.1740.10 203 287 3.7E-19 T 28-03-2018 CU254_RS25130 7d49a3ba405e03c8babdc3f0f413ea07 381 Gene3D G3DSA:1.10.10.10 288 379 4.3E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS25130 7d49a3ba405e03c8babdc3f0f413ea07 381 Gene3D G3DSA:1.10.10.10 51 148 2.4E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS36865 ff5d675f19bb85089c83983ce35a44a7 208 Gene3D G3DSA:1.20.120.450 1 173 4.8E-19 T 28-03-2018 CU254_RS36865 ff5d675f19bb85089c83983ce35a44a7 208 TIGRFAM TIGR03085 TIGR03085: TIGR03085 family protein 4 201 2.6E-70 T 28-03-2018 IPR017519 Conserved hypothetical protein CHP03085 CU254_RS36865 ff5d675f19bb85089c83983ce35a44a7 208 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 4 184 5.5E-35 T 28-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CU254_RS36865 ff5d675f19bb85089c83983ce35a44a7 208 SUPERFAMILY SSF109854 4 113 8.24E-7 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CU254_RS17785 fe845216a2659ad7a10fec1a1243e7ba 365 SUPERFAMILY SSF53756 5 364 1.74E-75 T 28-03-2018 CU254_RS17785 fe845216a2659ad7a10fec1a1243e7ba 365 Pfam PF13692 Glycosyl transferases group 1 196 329 3.6E-29 T 28-03-2018 CU254_RS17785 fe845216a2659ad7a10fec1a1243e7ba 365 Gene3D G3DSA:3.40.50.2000 197 355 6.2E-39 T 28-03-2018 CU254_RS17785 fe845216a2659ad7a10fec1a1243e7ba 365 Gene3D G3DSA:3.40.50.2000 2 196 8.2E-10 T 28-03-2018 CU254_RS17785 fe845216a2659ad7a10fec1a1243e7ba 365 Pfam PF13439 Glycosyltransferase Family 4 18 182 4.7E-18 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CU254_RS23975 783a168fb498a6666a8689241dcec270 401 SUPERFAMILY SSF53901 3 276 3.79E-61 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS23975 783a168fb498a6666a8689241dcec270 401 PIRSF PIRSF000429 2 401 5.8E-121 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CU254_RS23975 783a168fb498a6666a8689241dcec270 401 Gene3D G3DSA:3.40.47.10 2 272 3.4E-53 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS23975 783a168fb498a6666a8689241dcec270 401 SUPERFAMILY SSF53901 278 399 3.67E-42 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS23975 783a168fb498a6666a8689241dcec270 401 ProSitePatterns PS00737 Thiolases signature 2. 346 362 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CU254_RS23975 783a168fb498a6666a8689241dcec270 401 Pfam PF02803 Thiolase, C-terminal domain 278 399 9.2E-47 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CU254_RS23975 783a168fb498a6666a8689241dcec270 401 Gene3D G3DSA:3.40.47.10 273 397 2.8E-32 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS23975 783a168fb498a6666a8689241dcec270 401 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 398 1.1E-129 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CU254_RS23975 783a168fb498a6666a8689241dcec270 401 Pfam PF00108 Thiolase, N-terminal domain 5 268 1.2E-59 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CU254_RS35370 60943efb245fb6ab9f598970770ccc69 928 Gene3D G3DSA:1.25.40.10 102 261 5.2E-26 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS35370 60943efb245fb6ab9f598970770ccc69 928 Pfam PF00931 NB-ARC domain 297 474 1.1E-7 T 28-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 CU254_RS35370 60943efb245fb6ab9f598970770ccc69 928 Pfam PF13424 Tetratricopeptide repeat 758 827 4.1E-11 T 28-03-2018 CU254_RS35370 60943efb245fb6ab9f598970770ccc69 928 SUPERFAMILY SSF52540 261 526 1.23E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS35370 60943efb245fb6ab9f598970770ccc69 928 Gene3D G3DSA:3.30.70.100 695 752 2.2E-8 T 28-03-2018 CU254_RS35370 60943efb245fb6ab9f598970770ccc69 928 Gene3D G3DSA:1.10.10.10 514 589 0.0038 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS35370 60943efb245fb6ab9f598970770ccc69 928 SMART SM00862 21 93 3.6E-10 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS35370 60943efb245fb6ab9f598970770ccc69 928 SUPERFAMILY SSF48452 95 262 1.58E-34 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS35370 60943efb245fb6ab9f598970770ccc69 928 SUPERFAMILY SSF48452 707 906 4.93E-23 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS35370 60943efb245fb6ab9f598970770ccc69 928 SMART SM01043 100 245 6.6E-37 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CU254_RS35370 60943efb245fb6ab9f598970770ccc69 928 Pfam PF03704 Bacterial transcriptional activator domain 100 244 4.9E-39 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CU254_RS35370 60943efb245fb6ab9f598970770ccc69 928 Gene3D G3DSA:1.25.40.10 807 927 1.4E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS35370 60943efb245fb6ab9f598970770ccc69 928 PRINTS PR00364 Disease resistance protein signature 463 477 1.1E-8 T 28-03-2018 CU254_RS35370 60943efb245fb6ab9f598970770ccc69 928 PRINTS PR00364 Disease resistance protein signature 298 313 1.1E-8 T 28-03-2018 CU254_RS35370 60943efb245fb6ab9f598970770ccc69 928 PRINTS PR00364 Disease resistance protein signature 376 390 1.1E-8 T 28-03-2018 CU254_RS35370 60943efb245fb6ab9f598970770ccc69 928 Pfam PF00486 Transcriptional regulatory protein, C terminal 34 91 5.5E-7 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS35370 60943efb245fb6ab9f598970770ccc69 928 Gene3D G3DSA:3.40.50.300 262 420 5.4E-14 T 28-03-2018 CU254_RS35370 60943efb245fb6ab9f598970770ccc69 928 Gene3D G3DSA:1.10.10.10 4 101 1.4E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS35370 60943efb245fb6ab9f598970770ccc69 928 SMART SM00028 877 910 9.7 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS35370 60943efb245fb6ab9f598970770ccc69 928 SMART SM00028 105 138 200.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS35370 60943efb245fb6ab9f598970770ccc69 928 SMART SM00028 758 791 10.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS35370 60943efb245fb6ab9f598970770ccc69 928 SMART SM00028 718 751 23.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS35370 60943efb245fb6ab9f598970770ccc69 928 SMART SM00028 798 831 0.91 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS35370 60943efb245fb6ab9f598970770ccc69 928 SUPERFAMILY SSF46894 8 93 1.25E-12 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS35370 60943efb245fb6ab9f598970770ccc69 928 Gene3D G3DSA:1.10.150.200 753 806 4.0E-7 T 28-03-2018 CU254_RS33510 5641c9e9f73b5bcdadb8533fd6e056bc 477 Pfam PF00561 alpha/beta hydrolase fold 51 419 1.3E-24 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS33510 5641c9e9f73b5bcdadb8533fd6e056bc 477 Gene3D G3DSA:3.40.50.1820 1 442 4.2E-43 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS33510 5641c9e9f73b5bcdadb8533fd6e056bc 477 SUPERFAMILY SSF53474 283 304 4.09E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS33510 5641c9e9f73b5bcdadb8533fd6e056bc 477 SUPERFAMILY SSF53474 372 422 4.09E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS33510 5641c9e9f73b5bcdadb8533fd6e056bc 477 SUPERFAMILY SSF53474 26 97 4.09E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS33510 5641c9e9f73b5bcdadb8533fd6e056bc 477 SUPERFAMILY SSF53474 135 200 4.09E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS39075 480853e7cbe3570ad7561eaade426749 933 Pfam PF09334 tRNA synthetases class I (M) 45 149 7.8E-14 T 28-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 CU254_RS39075 480853e7cbe3570ad7561eaade426749 933 Pfam PF08264 Anticodon-binding domain of tRNA 783 897 2.7E-16 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CU254_RS39075 480853e7cbe3570ad7561eaade426749 933 Gene3D G3DSA:1.10.730.10 731 870 3.2E-25 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CU254_RS39075 480853e7cbe3570ad7561eaade426749 933 SUPERFAMILY SSF50677 280 482 5.34E-45 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CU254_RS39075 480853e7cbe3570ad7561eaade426749 933 SUPERFAMILY SSF52374 5 153 2.29E-107 T 28-03-2018 CU254_RS39075 480853e7cbe3570ad7561eaade426749 933 SUPERFAMILY SSF52374 483 750 2.29E-107 T 28-03-2018 CU254_RS39075 480853e7cbe3570ad7561eaade426749 933 SUPERFAMILY SSF52374 201 279 2.29E-107 T 28-03-2018 CU254_RS39075 480853e7cbe3570ad7561eaade426749 933 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 200 933 3.5E-218 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CU254_RS39075 480853e7cbe3570ad7561eaade426749 933 PRINTS PR00985 Leucyl-tRNA synthetase signature 239 252 9.6E-54 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CU254_RS39075 480853e7cbe3570ad7561eaade426749 933 PRINTS PR00985 Leucyl-tRNA synthetase signature 567 585 9.6E-54 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CU254_RS39075 480853e7cbe3570ad7561eaade426749 933 PRINTS PR00985 Leucyl-tRNA synthetase signature 206 222 9.6E-54 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CU254_RS39075 480853e7cbe3570ad7561eaade426749 933 PRINTS PR00985 Leucyl-tRNA synthetase signature 268 287 9.6E-54 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CU254_RS39075 480853e7cbe3570ad7561eaade426749 933 PRINTS PR00985 Leucyl-tRNA synthetase signature 652 662 9.6E-54 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CU254_RS39075 480853e7cbe3570ad7561eaade426749 933 PRINTS PR00985 Leucyl-tRNA synthetase signature 619 641 9.6E-54 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CU254_RS39075 480853e7cbe3570ad7561eaade426749 933 PRINTS PR00985 Leucyl-tRNA synthetase signature 133 150 9.6E-54 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CU254_RS39075 480853e7cbe3570ad7561eaade426749 933 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 274 471 2.0E-56 T 28-03-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 CU254_RS39075 480853e7cbe3570ad7561eaade426749 933 SUPERFAMILY SSF47323 745 932 5.98E-37 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CU254_RS39075 480853e7cbe3570ad7561eaade426749 933 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 1 933 21.325 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CU254_RS39075 480853e7cbe3570ad7561eaade426749 933 Gene3D G3DSA:3.90.740.10 284 469 2.5E-52 T 28-03-2018 CU254_RS39075 480853e7cbe3570ad7561eaade426749 933 Gene3D G3DSA:3.40.50.620 2 283 1.6E-58 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS39075 480853e7cbe3570ad7561eaade426749 933 Gene3D G3DSA:3.40.50.620 470 730 3.0E-55 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 Gene3D G3DSA:3.30.70.250 697 739 3.5E-15 T 28-03-2018 CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 Gene3D G3DSA:3.40.50.720 3014 3446 2.1E-65 T 28-03-2018 CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 Gene3D G3DSA:1.10.1200.10 1591 1699 2.4E-19 T 28-03-2018 CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 SUPERFAMILY SSF52151 561 681 2.28E-70 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 SUPERFAMILY SSF52151 738 839 2.28E-70 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 Gene3D G3DSA:3.10.129.10 915 1037 2.7E-7 T 28-03-2018 CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 Gene3D G3DSA:3.10.129.10 2572 2702 8.7E-7 T 28-03-2018 CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 SMART SM00823 Phosphopantetheine attachment site 1620 1692 4.7E-30 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 SMART SM00823 Phosphopantetheine attachment site 3303 3375 1.7E-26 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 SUPERFAMILY SSF52151 2224 2350 6.28E-70 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 SUPERFAMILY SSF52151 2407 2501 6.28E-70 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 Pfam PF00698 Acyl transferase domain 563 864 1.4E-54 T 28-03-2018 IPR014043 Acyl transferase CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 Pfam PF00698 Acyl transferase domain 2227 2533 4.4E-55 T 28-03-2018 IPR014043 Acyl transferase CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 SUPERFAMILY SSF55048 686 739 2.09E-9 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 Gene3D G3DSA:3.30.70.250 2356 2391 4.6E-12 T 28-03-2018 CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 Pfam PF08659 KR domain 1340 1516 2.4E-57 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 Pfam PF08659 KR domain 3025 3199 6.1E-56 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 Gene3D G3DSA:3.40.366.10 740 857 2.0E-23 T 28-03-2018 CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 Gene3D G3DSA:3.40.366.10 2392 2528 8.9E-40 T 28-03-2018 CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 SUPERFAMILY SSF55048 2349 2405 2.09E-8 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1647 1662 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 SMART SM01294 3303 3371 0.0012 T 28-03-2018 CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 SMART SM01294 1621 1688 6.4E-5 T 28-03-2018 CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3025 3201 6.5E-54 T 28-03-2018 CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1340 1518 8.4E-55 T 28-03-2018 CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 204 220 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 SUPERFAMILY SSF47336 1615 1725 1.57E-24 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 SUPERFAMILY SSF51735 2852 3012 7.48E-26 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 SUPERFAMILY SSF47336 3298 3381 1.2E-17 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 SMART SM00825 Beta-ketoacyl synthase 41 467 7.2E-211 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 SMART SM00825 Beta-ketoacyl synthase 1712 2124 1.5E-206 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 Pfam PF14765 Polyketide synthase dehydratase 913 1180 6.9E-53 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 Pfam PF14765 Polyketide synthase dehydratase 2574 2844 1.6E-59 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 Gene3D G3DSA:3.40.50.720 1335 1582 9.1E-48 T 28-03-2018 CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 Pfam PF08990 Erythronolide synthase docking 7 31 3.7E-9 T 28-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1859 1875 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 39 291 7.3E-88 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1710 1946 4.3E-82 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 SMART SM00826 2574 2735 1.2E-77 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 SMART SM00826 913 1074 9.8E-78 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1954 2071 2.4E-44 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 299 414 7.7E-43 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 SUPERFAMILY SSF51735 1336 1574 9.04E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 Gene3D G3DSA:3.40.47.10 1700 1951 1.6E-78 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 564 846 1.8E-118 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2228 2513 2.0E-107 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 Pfam PF00550 Phosphopantetheine attachment site 3306 3371 1.0E-8 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 Pfam PF00550 Phosphopantetheine attachment site 1622 1688 1.3E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 Gene3D G3DSA:3.40.366.10 560 696 1.7E-43 T 28-03-2018 CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 Gene3D G3DSA:3.40.366.10 2224 2355 1.7E-40 T 28-03-2018 CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 SUPERFAMILY SSF53901 35 160 6.75E-98 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 SUPERFAMILY SSF53901 187 411 6.75E-98 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 417 510 3.8E-10 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2074 2185 7.5E-15 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 Gene3D G3DSA:3.40.47.10 31 303 1.1E-82 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 SUPERFAMILY SSF51735 3021 3264 9.63E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 Gene3D G3DSA:3.40.47.10 1961 2122 3.3E-61 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 Gene3D G3DSA:3.40.47.10 306 465 4.5E-60 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 SUPERFAMILY SSF51735 1172 1328 5.51E-24 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS30045 c544a661920b03f66b966a3aa37d958f 3458 SUPERFAMILY SSF53901 1707 2070 2.11E-103 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS11345 030a042828938848524b82d2208f338e 188 SUPERFAMILY SSF81301 27 186 6.21E-46 T 28-03-2018 CU254_RS11345 030a042828938848524b82d2208f338e 188 Pfam PF04229 GrpB protein 26 184 2.5E-49 T 28-03-2018 IPR007344 GrpB/Dephospho-CoA kinase CU254_RS11345 030a042828938848524b82d2208f338e 188 Gene3D G3DSA:3.30.460.10 21 188 4.8E-53 T 28-03-2018 CU254_RS39840 af7653e050f4c55721bf1e98cbaf6aab 373 Pfam PF13581 Histidine kinase-like ATPase domain 290 334 2.0E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS39840 af7653e050f4c55721bf1e98cbaf6aab 373 SMART SM00387 282 371 1.3E-4 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS39840 af7653e050f4c55721bf1e98cbaf6aab 373 Pfam PF07730 Histidine kinase 178 243 1.2E-18 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CU254_RS39840 af7653e050f4c55721bf1e98cbaf6aab 373 SUPERFAMILY SSF55874 257 368 3.73E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS39840 af7653e050f4c55721bf1e98cbaf6aab 373 Gene3D G3DSA:3.30.565.10 247 373 5.6E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS14090 094853e7a651ec1228a22485ee86725b 478 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 35 452 6.8E-39 T 28-03-2018 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 CU254_RS14090 094853e7a651ec1228a22485ee86725b 478 PIRSF PIRSF002744 2 478 3.9E-93 T 28-03-2018 IPR026030 Purine-cytosine permease Fcy2/21/22 GO:0005215|GO:0016021|GO:0055085 CU254_RS04820 73dba037380ac9876c37b26e0ea3649e 996 Gene3D G3DSA:1.20.1250.20 157 316 7.3E-4 T 28-03-2018 CU254_RS04820 73dba037380ac9876c37b26e0ea3649e 996 Hamap MF_01600 UPF0182 protein . 10 905 17.812 T 28-03-2018 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 CU254_RS04820 73dba037380ac9876c37b26e0ea3649e 996 Pfam PF03699 Uncharacterised protein family (UPF0182) 19 829 8.7E-271 T 28-03-2018 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 CU254_RS13670 fbd75c051536e5f32b6230c4cffe0d01 400 SUPERFAMILY SSF53098 232 392 4.25E-34 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS13670 fbd75c051536e5f32b6230c4cffe0d01 400 Gene3D G3DSA:3.30.420.10 229 399 5.7E-33 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS13670 fbd75c051536e5f32b6230c4cffe0d01 400 Pfam PF13276 HTH-like domain 161 214 9.3E-15 T 28-03-2018 IPR025948 HTH-like domain CU254_RS13670 fbd75c051536e5f32b6230c4cffe0d01 400 Pfam PF00665 Integrase core domain 238 352 4.2E-22 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CU254_RS07150 fbd75c051536e5f32b6230c4cffe0d01 400 SUPERFAMILY SSF53098 232 392 4.25E-34 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS07150 fbd75c051536e5f32b6230c4cffe0d01 400 Gene3D G3DSA:3.30.420.10 229 399 5.7E-33 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS07150 fbd75c051536e5f32b6230c4cffe0d01 400 Pfam PF13276 HTH-like domain 161 214 9.3E-15 T 28-03-2018 IPR025948 HTH-like domain CU254_RS07150 fbd75c051536e5f32b6230c4cffe0d01 400 Pfam PF00665 Integrase core domain 238 352 4.2E-22 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CU254_RS16025 fbd75c051536e5f32b6230c4cffe0d01 400 SUPERFAMILY SSF53098 232 392 4.25E-34 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS16025 fbd75c051536e5f32b6230c4cffe0d01 400 Gene3D G3DSA:3.30.420.10 229 399 5.7E-33 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS16025 fbd75c051536e5f32b6230c4cffe0d01 400 Pfam PF13276 HTH-like domain 161 214 9.3E-15 T 28-03-2018 IPR025948 HTH-like domain CU254_RS16025 fbd75c051536e5f32b6230c4cffe0d01 400 Pfam PF00665 Integrase core domain 238 352 4.2E-22 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CU254_RS04080 fbd75c051536e5f32b6230c4cffe0d01 400 SUPERFAMILY SSF53098 232 392 4.25E-34 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS04080 fbd75c051536e5f32b6230c4cffe0d01 400 Gene3D G3DSA:3.30.420.10 229 399 5.7E-33 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS04080 fbd75c051536e5f32b6230c4cffe0d01 400 Pfam PF13276 HTH-like domain 161 214 9.3E-15 T 28-03-2018 IPR025948 HTH-like domain CU254_RS04080 fbd75c051536e5f32b6230c4cffe0d01 400 Pfam PF00665 Integrase core domain 238 352 4.2E-22 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CU254_RS28105 fbd75c051536e5f32b6230c4cffe0d01 400 SUPERFAMILY SSF53098 232 392 4.25E-34 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS28105 fbd75c051536e5f32b6230c4cffe0d01 400 Gene3D G3DSA:3.30.420.10 229 399 5.7E-33 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS28105 fbd75c051536e5f32b6230c4cffe0d01 400 Pfam PF13276 HTH-like domain 161 214 9.3E-15 T 28-03-2018 IPR025948 HTH-like domain CU254_RS28105 fbd75c051536e5f32b6230c4cffe0d01 400 Pfam PF00665 Integrase core domain 238 352 4.2E-22 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CU254_RS17980 fbd75c051536e5f32b6230c4cffe0d01 400 SUPERFAMILY SSF53098 232 392 4.25E-34 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS17980 fbd75c051536e5f32b6230c4cffe0d01 400 Gene3D G3DSA:3.30.420.10 229 399 5.7E-33 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS17980 fbd75c051536e5f32b6230c4cffe0d01 400 Pfam PF13276 HTH-like domain 161 214 9.3E-15 T 28-03-2018 IPR025948 HTH-like domain CU254_RS17980 fbd75c051536e5f32b6230c4cffe0d01 400 Pfam PF00665 Integrase core domain 238 352 4.2E-22 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CU254_RS13515 fb533fb86648f827dca5a30146175930 230 Gene3D G3DSA:1.10.10.10 122 229 3.9E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS13515 fb533fb86648f827dca5a30146175930 230 SMART SM00448 2 112 8.5E-44 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS13515 fb533fb86648f827dca5a30146175930 230 Gene3D G3DSA:3.40.50.2300 1 121 3.1E-38 T 28-03-2018 CU254_RS13515 fb533fb86648f827dca5a30146175930 230 SUPERFAMILY SSF46894 125 227 8.79E-27 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS13515 fb533fb86648f827dca5a30146175930 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 227 5.6E-23 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS13515 fb533fb86648f827dca5a30146175930 230 SMART SM00862 151 227 3.9E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS13515 fb533fb86648f827dca5a30146175930 230 Pfam PF00072 Response regulator receiver domain 4 112 6.7E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS13515 fb533fb86648f827dca5a30146175930 230 SUPERFAMILY SSF52172 1 120 8.97E-42 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS17210 d1dd24ec620f68ac0998764c856637dc 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 54 2.3E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS17210 d1dd24ec620f68ac0998764c856637dc 212 Gene3D G3DSA:1.10.357.10 59 186 9.9E-6 T 28-03-2018 CU254_RS17210 d1dd24ec620f68ac0998764c856637dc 212 SUPERFAMILY SSF48498 76 181 2.05E-6 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS17210 d1dd24ec620f68ac0998764c856637dc 212 SUPERFAMILY SSF46689 3 79 7.7E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS17210 d1dd24ec620f68ac0998764c856637dc 212 Gene3D G3DSA:1.10.260.40 37 58 1.7E-8 T 28-03-2018 CU254_RS17210 d1dd24ec620f68ac0998764c856637dc 212 Gene3D G3DSA:1.10.10.60 2 36 7.7E-13 T 28-03-2018 CU254_RS04225 18043e84f6d7e90fc01033be9a29b00f 166 Pfam PF01202 Shikimate kinase 12 149 7.8E-13 T 28-03-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CU254_RS04225 18043e84f6d7e90fc01033be9a29b00f 166 SUPERFAMILY SSF52540 2 163 3.47E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS04225 18043e84f6d7e90fc01033be9a29b00f 166 Gene3D G3DSA:3.40.50.300 2 166 1.3E-28 T 28-03-2018 CU254_RS04225 18043e84f6d7e90fc01033be9a29b00f 166 TIGRFAM TIGR01313 therm_gnt_kin: carbohydrate kinase, thermoresistant glucokinase family 6 161 1.8E-54 T 28-03-2018 IPR006001 Carbohydrate kinase, thermoresistant glucokinase GO:0005975|GO:0016301 KEGG: 00030+2.7.1.12|MetaCyc: PWY-5530 CU254_RS00270 ae2bb0d4276b13eeb7d679812e4cbb0e 363 SUPERFAMILY SSF51735 151 329 1.21E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS00270 ae2bb0d4276b13eeb7d679812e4cbb0e 363 Pfam PF00107 Zinc-binding dehydrogenase 186 320 1.1E-21 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CU254_RS00270 ae2bb0d4276b13eeb7d679812e4cbb0e 363 SUPERFAMILY SSF50129 39 171 9.63E-32 T 28-03-2018 IPR011032 GroES-like CU254_RS00270 ae2bb0d4276b13eeb7d679812e4cbb0e 363 SMART SM00829 48 361 3.4E-6 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CU254_RS00270 ae2bb0d4276b13eeb7d679812e4cbb0e 363 Gene3D G3DSA:3.40.50.720 177 305 1.3E-27 T 28-03-2018 CU254_RS00270 ae2bb0d4276b13eeb7d679812e4cbb0e 363 Pfam PF16884 N-terminal domain of oxidoreductase 42 138 5.2E-29 T 28-03-2018 CU254_RS00270 ae2bb0d4276b13eeb7d679812e4cbb0e 363 Gene3D G3DSA:3.90.180.10 32 176 7.1E-32 T 28-03-2018 CU254_RS34095 ed348baa95cc410257532d90db545125 108 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 8 100 1.6E-6 T 28-03-2018 IPR022536 ESX-1 secretion-associated protein EspC GO:0009306 CU254_RS34095 ed348baa95cc410257532d90db545125 108 Gene3D G3DSA:1.10.287.1060 3 103 6.2E-7 T 28-03-2018 CU254_RS22885 a7d8e0f45c6f2fa53d6e4fafdf8c4399 237 Gene3D G3DSA:3.40.50.300 1 234 9.6E-57 T 28-03-2018 CU254_RS22885 a7d8e0f45c6f2fa53d6e4fafdf8c4399 237 PIRSF PIRSF039137 1 237 2.5E-108 T 28-03-2018 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 CU254_RS22885 a7d8e0f45c6f2fa53d6e4fafdf8c4399 237 Pfam PF00005 ABC transporter 21 164 1.4E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS22885 a7d8e0f45c6f2fa53d6e4fafdf8c4399 237 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS22885 a7d8e0f45c6f2fa53d6e4fafdf8c4399 237 SUPERFAMILY SSF52540 3 233 2.61E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS22885 a7d8e0f45c6f2fa53d6e4fafdf8c4399 237 SMART SM00382 28 215 2.0E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS17555 df057208b10392af8fd69e5db3d784bc 475 PIRSF PIRSF006060 3 474 9.8E-68 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CU254_RS17555 df057208b10392af8fd69e5db3d784bc 475 Pfam PF00324 Amino acid permease 21 453 2.7E-106 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CU254_RS17555 df057208b10392af8fd69e5db3d784bc 475 ProSitePatterns PS00218 Amino acid permeases signature. 46 76 - T 28-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CU254_RS25680 b894bcc5e1dcad193d4428a502062175 73 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 23.279 T 28-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 CU254_RS25680 b894bcc5e1dcad193d4428a502062175 73 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 7 71 1.7E-29 T 28-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 CU254_RS25680 b894bcc5e1dcad193d4428a502062175 73 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 1.1E-23 T 28-03-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 CU254_RS25680 b894bcc5e1dcad193d4428a502062175 73 Gene3D G3DSA:2.40.50.140 1 72 1.8E-31 T 28-03-2018 CU254_RS25680 b894bcc5e1dcad193d4428a502062175 73 SUPERFAMILY SSF50249 3 73 1.06E-23 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CU254_RS25680 b894bcc5e1dcad193d4428a502062175 73 SMART SM00316 4 72 1.3E-6 T 28-03-2018 IPR022967 RNA-binding domain, S1 CU254_RS07995 b5c9b824895a35183adf4a542c119806 308 Pfam PF00717 Peptidase S24-like 70 116 2.4E-6 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CU254_RS07995 b5c9b824895a35183adf4a542c119806 308 SUPERFAMILY SSF51306 146 254 6.28E-43 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CU254_RS07995 b5c9b824895a35183adf4a542c119806 308 SUPERFAMILY SSF51306 62 114 6.28E-43 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CU254_RS07995 b5c9b824895a35183adf4a542c119806 308 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 49 247 7.7E-38 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CU254_RS07995 b5c9b824895a35183adf4a542c119806 308 Gene3D G3DSA:2.10.109.10 59 263 7.2E-43 T 28-03-2018 CU254_RS07995 b5c9b824895a35183adf4a542c119806 308 Pfam PF10502 Signal peptidase, peptidase S26 150 245 5.1E-9 T 28-03-2018 IPR019533 Peptidase S26 CU254_RS07995 b5c9b824895a35183adf4a542c119806 308 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 63 79 2.4E-19 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CU254_RS07995 b5c9b824895a35183adf4a542c119806 308 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 202 221 2.4E-19 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CU254_RS07995 b5c9b824895a35183adf4a542c119806 308 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 151 163 2.4E-19 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CU254_RS07995 b5c9b824895a35183adf4a542c119806 308 ProSitePatterns PS00761 Signal peptidases I signature 3. 207 220 - T 28-03-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 CU254_RS22525 189fc7283fd820e296c57db501fbfb96 127 Gene3D G3DSA:3.30.1330.40 1 127 1.6E-41 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CU254_RS22525 189fc7283fd820e296c57db501fbfb96 127 SUPERFAMILY SSF55298 3 126 1.38E-39 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CU254_RS22525 189fc7283fd820e296c57db501fbfb96 127 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 4 125 7.6E-33 T 28-03-2018 IPR006056 RidA family CU254_RS22525 189fc7283fd820e296c57db501fbfb96 127 Pfam PF01042 Endoribonuclease L-PSP 9 125 2.9E-32 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family CU254_RS29680 6455470f85eaa768f551f8515172de30 478 Gene3D G3DSA:3.40.309.10 267 458 5.9E-71 T 28-03-2018 CU254_RS29680 6455470f85eaa768f551f8515172de30 478 SUPERFAMILY SSF53720 2 476 3.53E-170 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CU254_RS29680 6455470f85eaa768f551f8515172de30 478 Pfam PF00171 Aldehyde dehydrogenase family 11 472 2.1E-170 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CU254_RS29680 6455470f85eaa768f551f8515172de30 478 Gene3D G3DSA:3.40.605.10 1 266 1.2E-100 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CU254_RS29680 6455470f85eaa768f551f8515172de30 478 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 248 255 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CU254_RS29980 bd13e0fb1f6241dd32d156e7fda75652 405 Gene3D G3DSA:1.10.10.10 75 160 6.9E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS29980 bd13e0fb1f6241dd32d156e7fda75652 405 Pfam PF04542 Sigma-70 region 2 19 78 4.7E-7 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS29980 bd13e0fb1f6241dd32d156e7fda75652 405 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 5 159 4.8E-12 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS29980 bd13e0fb1f6241dd32d156e7fda75652 405 Pfam PF08281 Sigma-70, region 4 106 157 6.6E-10 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS29980 bd13e0fb1f6241dd32d156e7fda75652 405 SUPERFAMILY SSF48452 304 393 6.96E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS29980 bd13e0fb1f6241dd32d156e7fda75652 405 Gene3D G3DSA:1.10.1740.10 2 74 8.2E-12 T 28-03-2018 CU254_RS29980 bd13e0fb1f6241dd32d156e7fda75652 405 SUPERFAMILY SSF88659 99 159 1.5E-10 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS29980 bd13e0fb1f6241dd32d156e7fda75652 405 Gene3D G3DSA:1.25.40.120 201 400 5.7E-12 T 28-03-2018 CU254_RS29980 bd13e0fb1f6241dd32d156e7fda75652 405 SUPERFAMILY SSF88946 5 80 2.35E-8 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS22620 90cb82eac968bb1f92af84ae8d879bca 953 ProSitePatterns PS00211 ABC transporters family signature. 498 512 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS22620 90cb82eac968bb1f92af84ae8d879bca 953 Gene3D G3DSA:3.40.50.300 624 951 4.2E-55 T 28-03-2018 CU254_RS22620 90cb82eac968bb1f92af84ae8d879bca 953 Gene3D G3DSA:3.40.50.300 1 36 2.6E-7 T 28-03-2018 CU254_RS22620 90cb82eac968bb1f92af84ae8d879bca 953 Hamap MF_00205 UvrABC system protein A [uvrA]. 2 950 22.74 T 28-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 CU254_RS22620 90cb82eac968bb1f92af84ae8d879bca 953 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 5 935 0.0 T 28-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 CU254_RS22620 90cb82eac968bb1f92af84ae8d879bca 953 Gene3D G3DSA:3.30.190.20 128 244 9.3E-43 T 28-03-2018 CU254_RS22620 90cb82eac968bb1f92af84ae8d879bca 953 Gene3D G3DSA:3.40.50.300 37 116 0.0019 T 28-03-2018 CU254_RS22620 90cb82eac968bb1f92af84ae8d879bca 953 SUPERFAMILY SSF52540 441 580 2.56E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS22620 90cb82eac968bb1f92af84ae8d879bca 953 SUPERFAMILY SSF52540 10 205 2.56E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS22620 90cb82eac968bb1f92af84ae8d879bca 953 Gene3D G3DSA:3.40.50.300 434 623 1.7E-22 T 28-03-2018 CU254_RS22620 90cb82eac968bb1f92af84ae8d879bca 953 Pfam PF00005 ABC transporter 634 870 4.3E-9 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS22620 90cb82eac968bb1f92af84ae8d879bca 953 SUPERFAMILY SSF52540 625 919 1.73E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS22620 90cb82eac968bb1f92af84ae8d879bca 953 Gene3D G3DSA:1.10.8.280 290 411 4.0E-39 T 28-03-2018 CU254_RS22620 90cb82eac968bb1f92af84ae8d879bca 953 ProSitePatterns PS00211 ABC transporters family signature. 840 854 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS16285 0e3e19bc8930f470dea6215464308eef 571 SUPERFAMILY SSF52540 327 561 7.08E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS16285 0e3e19bc8930f470dea6215464308eef 571 Gene3D G3DSA:3.40.50.300 329 567 8.2E-52 T 28-03-2018 CU254_RS16285 0e3e19bc8930f470dea6215464308eef 571 SMART SM00382 357 538 1.3E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS16285 0e3e19bc8930f470dea6215464308eef 571 Gene3D G3DSA:1.20.1560.10 1 319 5.8E-26 T 28-03-2018 CU254_RS16285 0e3e19bc8930f470dea6215464308eef 571 Pfam PF00005 ABC transporter 349 494 2.6E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS16285 0e3e19bc8930f470dea6215464308eef 571 ProSitePatterns PS00211 ABC transporters family signature. 466 480 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS16285 0e3e19bc8930f470dea6215464308eef 571 SUPERFAMILY SSF90123 12 310 4.45E-26 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CU254_RS31270 f50a44bd98077853b97414a655190830 545 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 366 375 - T 28-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CU254_RS31270 f50a44bd98077853b97414a655190830 545 SUPERFAMILY SSF52540 99 381 7.68E-92 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS31270 f50a44bd98077853b97414a655190830 545 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 29 95 5.3E-13 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CU254_RS31270 f50a44bd98077853b97414a655190830 545 SUPERFAMILY SSF47917 384 511 1.12E-46 T 28-03-2018 CU254_RS31270 f50a44bd98077853b97414a655190830 545 SUPERFAMILY SSF50615 14 97 1.07E-23 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CU254_RS31270 f50a44bd98077853b97414a655190830 545 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 6 512 6.4E-241 T 28-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CU254_RS31270 f50a44bd98077853b97414a655190830 545 Gene3D G3DSA:2.40.30.20 6 85 8.6E-29 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CU254_RS31270 f50a44bd98077853b97414a655190830 545 Gene3D G3DSA:3.40.50.300 86 375 6.0E-104 T 28-03-2018 CU254_RS31270 f50a44bd98077853b97414a655190830 545 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 4 512 48.621 T 28-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CU254_RS31270 f50a44bd98077853b97414a655190830 545 Gene3D G3DSA:1.20.150.20 384 511 1.6E-51 T 28-03-2018 CU254_RS31270 f50a44bd98077853b97414a655190830 545 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 382 507 1.0E-46 T 28-03-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CU254_RS31270 f50a44bd98077853b97414a655190830 545 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 152 375 1.6E-65 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CU254_RS37015 23dd842a65f41ee3064721ed88e986b7 366 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 238 306 1.6E-15 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CU254_RS37015 23dd842a65f41ee3064721ed88e986b7 366 Pfam PF00005 ABC transporter 35 186 1.7E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS37015 23dd842a65f41ee3064721ed88e986b7 366 SMART SM00382 43 236 2.9E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS37015 23dd842a65f41ee3064721ed88e986b7 366 SUPERFAMILY SSF52540 6 258 1.38E-72 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS37015 23dd842a65f41ee3064721ed88e986b7 366 Gene3D G3DSA:3.40.50.300 3 341 6.3E-84 T 28-03-2018 CU254_RS37015 23dd842a65f41ee3064721ed88e986b7 366 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 237 326 6.5E-26 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CU254_RS37015 23dd842a65f41ee3064721ed88e986b7 366 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS05865 3967b7d10c3e965e7930611b35a153e8 133 SUPERFAMILY SSF54427 7 124 1.5E-18 T 28-03-2018 IPR032710 NTF2-like domain CU254_RS05865 3967b7d10c3e965e7930611b35a153e8 133 Gene3D G3DSA:3.10.450.50 5 131 1.9E-23 T 28-03-2018 CU254_RS05865 3967b7d10c3e965e7930611b35a153e8 133 Pfam PF12680 SnoaL-like domain 10 107 1.2E-11 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CU254_RS13395 730ba85d26036b4bb4be1c2923194da3 690 Gene3D G3DSA:3.40.50.980 191 352 1.9E-32 T 28-03-2018 CU254_RS13395 730ba85d26036b4bb4be1c2923194da3 690 Pfam PF13193 AMP-binding enzyme C-terminal domain 600 674 9.6E-21 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS13395 730ba85d26036b4bb4be1c2923194da3 690 Gene3D G3DSA:2.30.38.10 504 583 1.3E-15 T 28-03-2018 CU254_RS13395 730ba85d26036b4bb4be1c2923194da3 690 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 6 139 6.5E-7 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase CU254_RS13395 730ba85d26036b4bb4be1c2923194da3 690 Gene3D G3DSA:3.40.50.980 353 503 1.1E-33 T 28-03-2018 CU254_RS13395 730ba85d26036b4bb4be1c2923194da3 690 Gene3D G3DSA:3.30.530.20 2 170 9.1E-16 T 28-03-2018 IPR023393 START-like domain CU254_RS13395 730ba85d26036b4bb4be1c2923194da3 690 SUPERFAMILY SSF55961 5 144 6.32E-16 T 28-03-2018 CU254_RS13395 730ba85d26036b4bb4be1c2923194da3 690 Pfam PF00501 AMP-binding enzyme 202 590 2.4E-70 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS13395 730ba85d26036b4bb4be1c2923194da3 690 ProSitePatterns PS00455 Putative AMP-binding domain signature. 347 358 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS13395 730ba85d26036b4bb4be1c2923194da3 690 SUPERFAMILY SSF56801 192 685 3.27E-125 T 28-03-2018 CU254_RS13395 730ba85d26036b4bb4be1c2923194da3 690 Gene3D G3DSA:3.30.300.30 584 685 4.5E-28 T 28-03-2018 CU254_RS16715 e1b4a6870385c12574a87d661c94e73c 1194 Gene3D G3DSA:2.160.20.10 808 1194 2.6E-33 T 28-03-2018 IPR012334 Pectin lyase fold CU254_RS16715 e1b4a6870385c12574a87d661c94e73c 1194 Gene3D G3DSA:2.60.40.10 409 515 7.0E-18 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS16715 e1b4a6870385c12574a87d661c94e73c 1194 Gene3D G3DSA:2.60.40.10 516 642 1.5E-8 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS16715 e1b4a6870385c12574a87d661c94e73c 1194 SMART SM00231 33 175 0.0089 T 28-03-2018 IPR000421 Coagulation factor 5/8 C-terminal domain CU254_RS16715 e1b4a6870385c12574a87d661c94e73c 1194 Gene3D G3DSA:2.60.120.260 643 807 1.8E-14 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS16715 e1b4a6870385c12574a87d661c94e73c 1194 SUPERFAMILY SSF49265 181 264 2.4E-6 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CU254_RS16715 e1b4a6870385c12574a87d661c94e73c 1194 SUPERFAMILY SSF49785 45 175 1.77E-25 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS16715 e1b4a6870385c12574a87d661c94e73c 1194 Pfam PF00754 F5/8 type C domain 50 169 7.6E-18 T 28-03-2018 IPR000421 Coagulation factor 5/8 C-terminal domain CU254_RS16715 e1b4a6870385c12574a87d661c94e73c 1194 Pfam PF00754 F5/8 type C domain 281 404 4.3E-10 T 28-03-2018 IPR000421 Coagulation factor 5/8 C-terminal domain CU254_RS16715 e1b4a6870385c12574a87d661c94e73c 1194 SUPERFAMILY SSF51126 821 1133 4.87E-31 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor CU254_RS16715 e1b4a6870385c12574a87d661c94e73c 1194 Gene3D G3DSA:2.60.120.260 30 171 3.6E-30 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS16715 e1b4a6870385c12574a87d661c94e73c 1194 Gene3D G3DSA:2.60.120.260 259 408 2.1E-26 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS16715 e1b4a6870385c12574a87d661c94e73c 1194 Pfam PF07705 CARDB 413 513 1.3E-25 T 28-03-2018 IPR011635 CARDB domain CU254_RS16715 e1b4a6870385c12574a87d661c94e73c 1194 Pfam PF07705 CARDB 526 630 7.7E-6 T 28-03-2018 IPR011635 CARDB domain CU254_RS16715 e1b4a6870385c12574a87d661c94e73c 1194 SMART SM00710 1020 1043 920.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CU254_RS16715 e1b4a6870385c12574a87d661c94e73c 1194 SMART SM00710 1090 1112 1600.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CU254_RS16715 e1b4a6870385c12574a87d661c94e73c 1194 SMART SM00710 1123 1153 1500.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CU254_RS16715 e1b4a6870385c12574a87d661c94e73c 1194 SMART SM00710 996 1019 5400.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CU254_RS16715 e1b4a6870385c12574a87d661c94e73c 1194 SMART SM00710 965 987 860.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CU254_RS16715 e1b4a6870385c12574a87d661c94e73c 1194 SMART SM00710 941 963 19.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CU254_RS16715 e1b4a6870385c12574a87d661c94e73c 1194 SUPERFAMILY SSF49785 271 408 1.63E-20 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS16715 e1b4a6870385c12574a87d661c94e73c 1194 Gene3D G3DSA:2.60.40.10 172 258 6.6E-14 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS19625 cae509e3363913385027b0739348341f 683 SUPERFAMILY SSF55486 14 679 1.63E-172 T 28-03-2018 CU254_RS19625 cae509e3363913385027b0739348341f 683 Gene3D G3DSA:1.10.1370.10 147 423 1.4E-41 T 28-03-2018 CU254_RS19625 cae509e3363913385027b0739348341f 683 Gene3D G3DSA:1.10.1370.10 460 683 3.5E-56 T 28-03-2018 CU254_RS19625 cae509e3363913385027b0739348341f 683 Gene3D G3DSA:1.20.1050.40 11 146 6.4E-41 T 28-03-2018 IPR024080 Neurolysin/Thimet oligopeptidase, N-terminal CU254_RS19625 cae509e3363913385027b0739348341f 683 Pfam PF01432 Peptidase family M3 232 679 3.5E-124 T 28-03-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 CU254_RS07290 680ec8d3f4ce1942a7a5f241e9f71107 267 SUPERFAMILY SSF53474 2 267 8.4E-58 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS07290 680ec8d3f4ce1942a7a5f241e9f71107 267 Pfam PF00561 alpha/beta hydrolase fold 20 254 6.7E-21 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS07290 680ec8d3f4ce1942a7a5f241e9f71107 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 45 60 5.1E-10 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS07290 680ec8d3f4ce1942a7a5f241e9f71107 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 90 103 5.1E-10 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS07290 680ec8d3f4ce1942a7a5f241e9f71107 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 211 225 5.1E-10 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS07290 680ec8d3f4ce1942a7a5f241e9f71107 267 Gene3D G3DSA:3.40.50.1820 1 267 4.7E-43 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS21605 59fcd875da8318b6bf2d075d36cb0cdb 703 Pfam PF00009 Elongation factor Tu GTP binding domain 22 288 4.4E-32 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CU254_RS21605 59fcd875da8318b6bf2d075d36cb0cdb 703 Gene3D G3DSA:2.40.30.10 295 415 2.3E-28 T 28-03-2018 CU254_RS21605 59fcd875da8318b6bf2d075d36cb0cdb 703 SUPERFAMILY SSF52540 19 288 9.57E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS21605 59fcd875da8318b6bf2d075d36cb0cdb 703 Gene3D G3DSA:3.40.50.300 16 294 1.2E-37 T 28-03-2018 CU254_RS21605 59fcd875da8318b6bf2d075d36cb0cdb 703 Pfam PF03144 Elongation factor Tu domain 2 330 406 1.5E-7 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CU254_RS21605 59fcd875da8318b6bf2d075d36cb0cdb 703 SUPERFAMILY SSF54980 420 495 4.32E-15 T 28-03-2018 IPR035647 EF-G domain III/V-like CU254_RS21605 59fcd875da8318b6bf2d075d36cb0cdb 703 SMART SM00382 22 160 4.1E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS21605 59fcd875da8318b6bf2d075d36cb0cdb 703 Gene3D G3DSA:3.30.70.240 629 700 2.4E-21 T 28-03-2018 CU254_RS21605 59fcd875da8318b6bf2d075d36cb0cdb 703 SMART SM00838 615 703 1.1E-24 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CU254_RS21605 59fcd875da8318b6bf2d075d36cb0cdb 703 SUPERFAMILY SSF50447 255 281 8.58E-25 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CU254_RS21605 59fcd875da8318b6bf2d075d36cb0cdb 703 SUPERFAMILY SSF50447 311 417 8.58E-25 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CU254_RS21605 59fcd875da8318b6bf2d075d36cb0cdb 703 SUPERFAMILY SSF54980 618 698 2.88E-21 T 28-03-2018 IPR035647 EF-G domain III/V-like CU254_RS21605 59fcd875da8318b6bf2d075d36cb0cdb 703 Gene3D G3DSA:3.30.230.10 507 628 2.0E-39 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CU254_RS21605 59fcd875da8318b6bf2d075d36cb0cdb 703 Pfam PF00679 Elongation factor G C-terminus 616 697 1.5E-20 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CU254_RS21605 59fcd875da8318b6bf2d075d36cb0cdb 703 Pfam PF14492 Elongation Factor G, domain II 420 484 7.0E-21 T 28-03-2018 CU254_RS21605 59fcd875da8318b6bf2d075d36cb0cdb 703 SMART SM00889 495 613 1.8E-56 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CU254_RS21605 59fcd875da8318b6bf2d075d36cb0cdb 703 Gene3D G3DSA:3.30.70.870 416 506 3.1E-16 T 28-03-2018 CU254_RS21605 59fcd875da8318b6bf2d075d36cb0cdb 703 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 23 154 6.8E-14 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CU254_RS21605 59fcd875da8318b6bf2d075d36cb0cdb 703 SUPERFAMILY SSF54211 496 611 1.04E-34 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CU254_RS21605 59fcd875da8318b6bf2d075d36cb0cdb 703 Pfam PF03764 Elongation factor G, domain IV 495 612 9.1E-39 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CU254_RS40515 d11c9c17de188d54caef85e4604f941c 218 SUPERFAMILY SSF52172 1 130 8.54E-27 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS40515 d11c9c17de188d54caef85e4604f941c 218 Gene3D G3DSA:3.40.50.2300 1 132 3.9E-23 T 28-03-2018 CU254_RS40515 d11c9c17de188d54caef85e4604f941c 218 SMART SM00448 2 110 3.2E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS40515 d11c9c17de188d54caef85e4604f941c 218 SUPERFAMILY SSF46785 154 200 1.6E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS40515 d11c9c17de188d54caef85e4604f941c 218 Pfam PF09339 IclR helix-turn-helix domain 162 199 2.9E-7 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS40515 d11c9c17de188d54caef85e4604f941c 218 PIRSF PIRSF006171 1 218 5.5E-70 T 28-03-2018 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0001071|GO:0003677|GO:0005737|GO:0009605 CU254_RS40515 d11c9c17de188d54caef85e4604f941c 218 Gene3D G3DSA:1.10.10.10 133 217 7.2E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS40515 d11c9c17de188d54caef85e4604f941c 218 Pfam PF00072 Response regulator receiver domain 5 110 3.7E-15 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS04060 ad540086a0019cbf313f75c140b29d0b 131 Gene3D G3DSA:2.40.350.10 1 131 3.6E-34 T 28-03-2018 IPR023159 SO1590-like domain CU254_RS04060 ad540086a0019cbf313f75c140b29d0b 131 Pfam PF11528 Protein of unknown function (DUF3224) 3 129 5.0E-30 T 28-03-2018 IPR021607 Protein of unknown function DUF3224 CU254_RS04060 ad540086a0019cbf313f75c140b29d0b 131 SUPERFAMILY SSF159238 3 131 5.36E-30 T 28-03-2018 IPR023159 SO1590-like domain CU254_RS04880 c9a989783a6a3b82a2d258c1f90ca9bd 377 Pfam PF13796 Putative sensor 21 126 1.3E-21 T 28-03-2018 IPR025828 Putative sensor domain CU254_RS04880 c9a989783a6a3b82a2d258c1f90ca9bd 377 SUPERFAMILY SSF55874 265 374 3.31E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS04880 c9a989783a6a3b82a2d258c1f90ca9bd 377 Pfam PF07730 Histidine kinase 187 253 3.4E-15 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CU254_RS04880 c9a989783a6a3b82a2d258c1f90ca9bd 377 Gene3D G3DSA:3.30.565.10 167 376 3.1E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS01945 6d877a40c8fd3c99a09fef450c8d1dd2 101 Pfam PF00338 Ribosomal protein S10p/S20e 7 100 9.4E-35 T 28-03-2018 IPR027486 Ribosomal protein S10 domain CU254_RS01945 6d877a40c8fd3c99a09fef450c8d1dd2 101 Gene3D G3DSA:3.30.70.600 4 101 3.0E-35 T 28-03-2018 IPR027486 Ribosomal protein S10 domain CU254_RS01945 6d877a40c8fd3c99a09fef450c8d1dd2 101 SMART SM01403 7 101 2.2E-55 T 28-03-2018 IPR027486 Ribosomal protein S10 domain CU254_RS01945 6d877a40c8fd3c99a09fef450c8d1dd2 101 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 101 24.603 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS01945 6d877a40c8fd3c99a09fef450c8d1dd2 101 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 3.7E-21 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS01945 6d877a40c8fd3c99a09fef450c8d1dd2 101 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 3.7E-21 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS01945 6d877a40c8fd3c99a09fef450c8d1dd2 101 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 3.7E-21 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS01945 6d877a40c8fd3c99a09fef450c8d1dd2 101 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 3.1E-46 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS01945 6d877a40c8fd3c99a09fef450c8d1dd2 101 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 28-03-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS01945 6d877a40c8fd3c99a09fef450c8d1dd2 101 SUPERFAMILY SSF54999 5 100 8.5E-37 T 28-03-2018 IPR027486 Ribosomal protein S10 domain CU254_RS31360 18671279b387ba90f5b033c8ea9c7ef6 75 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 69 31.98 T 28-03-2018 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS31360 18671279b387ba90f5b033c8ea9c7ef6 75 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 67 1.4E-34 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS31360 18671279b387ba90f5b033c8ea9c7ef6 75 Pfam PF01197 Ribosomal protein L31 1 66 1.5E-33 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS31360 18671279b387ba90f5b033c8ea9c7ef6 75 PRINTS PR01249 Ribosomal protein L31 signature 32 47 1.1E-22 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS31360 18671279b387ba90f5b033c8ea9c7ef6 75 PRINTS PR01249 Ribosomal protein L31 signature 2 19 1.1E-22 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS31360 18671279b387ba90f5b033c8ea9c7ef6 75 PRINTS PR01249 Ribosomal protein L31 signature 47 65 1.1E-22 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS31360 18671279b387ba90f5b033c8ea9c7ef6 75 ProSitePatterns PS01143 Ribosomal protein L31 signature. 36 57 - T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS31360 18671279b387ba90f5b033c8ea9c7ef6 75 SUPERFAMILY SSF143800 1 67 3.49E-27 T 28-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS34640 cde24b6996f460d74ecef8339a43da84 351 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 129 8.7E-29 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CU254_RS34640 cde24b6996f460d74ecef8339a43da84 351 Pfam PF00107 Zinc-binding dehydrogenase 176 305 8.6E-24 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CU254_RS34640 cde24b6996f460d74ecef8339a43da84 351 SUPERFAMILY SSF51735 138 308 4.34E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS34640 cde24b6996f460d74ecef8339a43da84 351 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CU254_RS34640 cde24b6996f460d74ecef8339a43da84 351 Gene3D G3DSA:3.40.50.10730 160 303 5.3E-31 T 28-03-2018 CU254_RS34640 cde24b6996f460d74ecef8339a43da84 351 Gene3D G3DSA:3.90.180.10 1 159 3.8E-47 T 28-03-2018 CU254_RS34640 cde24b6996f460d74ecef8339a43da84 351 SMART SM00829 10 348 7.3E-5 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CU254_RS34640 cde24b6996f460d74ecef8339a43da84 351 SUPERFAMILY SSF50129 1 167 3.42E-45 T 28-03-2018 IPR011032 GroES-like CU254_RS11295 93fe09b426522e158a7d43a5b47ce2b2 251 Gene3D G3DSA:3.60.21.10 3 240 2.5E-26 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CU254_RS11295 93fe09b426522e158a7d43a5b47ce2b2 251 SUPERFAMILY SSF56300 5 214 7.1E-39 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CU254_RS11295 93fe09b426522e158a7d43a5b47ce2b2 251 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 5 189 3.2E-21 T 28-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 CU254_RS11295 93fe09b426522e158a7d43a5b47ce2b2 251 PIRSF PIRSF000883 3 229 5.3E-40 T 28-03-2018 IPR011152 Phosphoesterase MJ0912 CU254_RS11735 73899226e2969b07a143f75b34f7e864 699 Gene3D G3DSA:3.40.50.970 384 571 5.6E-45 T 28-03-2018 CU254_RS11735 73899226e2969b07a143f75b34f7e864 699 ProSitePatterns PS00801 Transketolase signature 1. 33 53 - T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CU254_RS11735 73899226e2969b07a143f75b34f7e864 699 SUPERFAMILY SSF52518 20 346 4.67E-102 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS11735 73899226e2969b07a143f75b34f7e864 699 Pfam PF02779 Transketolase, pyrimidine binding domain 376 556 6.2E-47 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CU254_RS11735 73899226e2969b07a143f75b34f7e864 699 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 25 360 7.2E-141 T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CU254_RS11735 73899226e2969b07a143f75b34f7e864 699 Gene3D G3DSA:3.40.50.970 5 383 4.6E-91 T 28-03-2018 CU254_RS11735 73899226e2969b07a143f75b34f7e864 699 Gene3D G3DSA:3.40.50.920 572 699 5.8E-31 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CU254_RS11735 73899226e2969b07a143f75b34f7e864 699 SUPERFAMILY SSF52518 372 559 7.25E-69 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS11735 73899226e2969b07a143f75b34f7e864 699 SUPERFAMILY SSF52922 562 696 7.2E-41 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CU254_RS11735 73899226e2969b07a143f75b34f7e864 699 ProSitePatterns PS00802 Transketolase signature 2. 499 515 - T 28-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CU254_RS11735 73899226e2969b07a143f75b34f7e864 699 Pfam PF02780 Transketolase, C-terminal domain 578 686 2.6E-13 T 28-03-2018 IPR033248 Transketolase, C-terminal domain CU254_RS11735 73899226e2969b07a143f75b34f7e864 699 SMART SM00861 377 557 1.9E-69 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CU254_RS11735 73899226e2969b07a143f75b34f7e864 699 TIGRFAM TIGR00232 tktlase_bact: transketolase 28 692 6.1E-247 T 28-03-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 CU254_RS37970 9c9ec4b0323ec0c0da80a0fdde76db9e 390 SMART SM00267 201 379 3.5E-57 T 28-03-2018 IPR000160 GGDEF domain CU254_RS37970 9c9ec4b0323ec0c0da80a0fdde76db9e 390 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 208 377 6.1E-52 T 28-03-2018 IPR000160 GGDEF domain CU254_RS37970 9c9ec4b0323ec0c0da80a0fdde76db9e 390 Gene3D G3DSA:3.30.70.270 205 385 1.7E-54 T 28-03-2018 CU254_RS37970 9c9ec4b0323ec0c0da80a0fdde76db9e 390 SUPERFAMILY SSF55073 218 377 7.85E-47 T 28-03-2018 IPR029787 Nucleotide cyclase CU254_RS37970 9c9ec4b0323ec0c0da80a0fdde76db9e 390 Pfam PF00990 Diguanylate cyclase, GGDEF domain 212 375 1.7E-44 T 28-03-2018 IPR000160 GGDEF domain CU254_RS33760 0365739b861d2a27c213d0217e8bbaf4 326 Pfam PF14572 Phosphoribosyl synthetase-associated domain 216 322 1.4E-21 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CU254_RS33760 0365739b861d2a27c213d0217e8bbaf4 326 SMART SM01400 12 128 4.5E-69 T 28-03-2018 CU254_RS33760 0365739b861d2a27c213d0217e8bbaf4 326 SUPERFAMILY SSF53271 77 314 4.16E-60 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CU254_RS33760 0365739b861d2a27c213d0217e8bbaf4 326 Gene3D G3DSA:3.40.50.2020 166 299 4.2E-35 T 28-03-2018 CU254_RS33760 0365739b861d2a27c213d0217e8bbaf4 326 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 12 128 3.3E-44 T 28-03-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CU254_RS33760 0365739b861d2a27c213d0217e8bbaf4 326 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 13 323 9.3E-116 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CU254_RS33760 0365739b861d2a27c213d0217e8bbaf4 326 Gene3D G3DSA:3.40.50.2020 9 165 1.1E-61 T 28-03-2018 CU254_RS33760 0365739b861d2a27c213d0217e8bbaf4 326 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 136 151 - T 28-03-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 CU254_RS33760 0365739b861d2a27c213d0217e8bbaf4 326 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 12 323 45.225 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CU254_RS22165 22d7d95fe5a200bc671d966af4416b6a 769 Gene3D G3DSA:1.50.10.100 26 402 4.2E-88 T 28-03-2018 CU254_RS22165 22d7d95fe5a200bc671d966af4416b6a 769 Gene3D G3DSA:2.60.220.10 684 764 2.0E-11 T 28-03-2018 CU254_RS22165 22d7d95fe5a200bc671d966af4416b6a 769 Pfam PF02278 Polysaccharide lyase family 8, super-sandwich domain 418 673 2.2E-71 T 28-03-2018 IPR003159 Polysaccharide lyase family 8, central domain GO:0005576|GO:0016829 CU254_RS22165 22d7d95fe5a200bc671d966af4416b6a 769 SUPERFAMILY SSF74650 418 673 4.55E-67 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CU254_RS22165 22d7d95fe5a200bc671d966af4416b6a 769 SUPERFAMILY SSF48230 417 438 4.58E-71 T 28-03-2018 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 CU254_RS22165 22d7d95fe5a200bc671d966af4416b6a 769 SUPERFAMILY SSF48230 50 378 4.58E-71 T 28-03-2018 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 CU254_RS22165 22d7d95fe5a200bc671d966af4416b6a 769 SUPERFAMILY SSF49863 685 768 6.54E-13 T 28-03-2018 IPR011071 Polysaccharide lyase family 8-like, C-terminal GO:0005975 CU254_RS22165 22d7d95fe5a200bc671d966af4416b6a 769 Pfam PF08124 Polysaccharide lyase family 8, N terminal alpha-helical domain 56 363 5.2E-65 T 28-03-2018 IPR012970 Polysaccharide lyase 8, N-terminal alpha-helical CU254_RS22165 22d7d95fe5a200bc671d966af4416b6a 769 Pfam PF02884 Polysaccharide lyase family 8, C-terminal beta-sandwich domain 688 743 1.9E-8 T 28-03-2018 IPR004103 Polysaccharide lyase family 8, C-terminal GO:0005576|GO:0016829 CU254_RS22165 22d7d95fe5a200bc671d966af4416b6a 769 Gene3D G3DSA:2.70.98.10 416 683 3.9E-80 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 CU254_RS38315 3d906de2e65aedba1264cffe6d9ffb26 621 Gene3D G3DSA:3.30.420.40 1 171 9.8E-69 T 28-03-2018 CU254_RS38315 3d906de2e65aedba1264cffe6d9ffb26 621 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 168 181 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CU254_RS38315 3d906de2e65aedba1264cffe6d9ffb26 621 SUPERFAMILY SSF100920 358 514 1.57E-59 T 28-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 CU254_RS38315 3d906de2e65aedba1264cffe6d9ffb26 621 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 310 324 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CU254_RS38315 3d906de2e65aedba1264cffe6d9ffb26 621 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 617 36.242 T 28-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 CU254_RS38315 3d906de2e65aedba1264cffe6d9ffb26 621 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CU254_RS38315 3d906de2e65aedba1264cffe6d9ffb26 621 SUPERFAMILY SSF53067 162 356 2.27E-63 T 28-03-2018 CU254_RS38315 3d906de2e65aedba1264cffe6d9ffb26 621 Pfam PF00012 Hsp70 protein 79 577 2.0E-218 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CU254_RS38315 3d906de2e65aedba1264cffe6d9ffb26 621 Gene3D G3DSA:1.20.1270.10 506 590 2.5E-25 T 28-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain CU254_RS38315 3d906de2e65aedba1264cffe6d9ffb26 621 SUPERFAMILY SSF100934 508 577 3.22E-5 T 28-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain CU254_RS38315 3d906de2e65aedba1264cffe6d9ffb26 621 Gene3D G3DSA:2.60.34.10 364 505 7.9E-70 T 28-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 CU254_RS38315 3d906de2e65aedba1264cffe6d9ffb26 621 SUPERFAMILY SSF53067 4 160 3.72E-58 T 28-03-2018 CU254_RS38315 3d906de2e65aedba1264cffe6d9ffb26 621 Gene3D G3DSA:3.30.420.40 172 334 4.5E-49 T 28-03-2018 CU254_RS38315 3d906de2e65aedba1264cffe6d9ffb26 621 PRINTS PR00301 70kDa heat shock protein signature 307 323 2.2E-75 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CU254_RS38315 3d906de2e65aedba1264cffe6d9ffb26 621 PRINTS PR00301 70kDa heat shock protein signature 443 459 2.2E-75 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CU254_RS38315 3d906de2e65aedba1264cffe6d9ffb26 621 PRINTS PR00301 70kDa heat shock protein signature 31 43 2.2E-75 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CU254_RS38315 3d906de2e65aedba1264cffe6d9ffb26 621 PRINTS PR00301 70kDa heat shock protein signature 114 134 2.2E-75 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CU254_RS38315 3d906de2e65aedba1264cffe6d9ffb26 621 PRINTS PR00301 70kDa heat shock protein signature 174 184 2.2E-75 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CU254_RS38315 3d906de2e65aedba1264cffe6d9ffb26 621 PRINTS PR00301 70kDa heat shock protein signature 362 381 2.2E-75 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CU254_RS38315 3d906de2e65aedba1264cffe6d9ffb26 621 PRINTS PR00301 70kDa heat shock protein signature 3 16 2.2E-75 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CU254_RS38315 3d906de2e65aedba1264cffe6d9ffb26 621 PRINTS PR00301 70kDa heat shock protein signature 54 62 2.2E-75 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CU254_RS38315 3d906de2e65aedba1264cffe6d9ffb26 621 PRINTS PR00301 70kDa heat shock protein signature 339 359 2.2E-75 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CU254_RS38315 3d906de2e65aedba1264cffe6d9ffb26 621 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 4 577 5.7E-278 T 28-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 CU254_RS06600 2335adb0f8b2efa799a70c5c60575378 174 Gene3D G3DSA:1.10.10.60 44 164 1.7E-9 T 28-03-2018 CU254_RS06600 2335adb0f8b2efa799a70c5c60575378 174 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 2.0E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS06600 2335adb0f8b2efa799a70c5c60575378 174 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 2.0E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS06600 2335adb0f8b2efa799a70c5c60575378 174 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 55 2.0E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS06600 2335adb0f8b2efa799a70c5c60575378 174 Gene3D G3DSA:1.10.10.60 3 43 8.0E-19 T 28-03-2018 CU254_RS06600 2335adb0f8b2efa799a70c5c60575378 174 ProSitePatterns PS01081 TetR-type HTH domain signature. 21 51 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CU254_RS06600 2335adb0f8b2efa799a70c5c60575378 174 SUPERFAMILY SSF46689 3 76 2.0E-19 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS35325 2bf0545b9c4fa367c2ac4bd7008d9da5 546 Pfam PF09286 Pro-kumamolisin, activation domain 43 182 6.4E-32 T 28-03-2018 IPR015366 Peptidase S53, activation domain GO:0008236 Reactome: R-HSA-381038 CU254_RS35325 2bf0545b9c4fa367c2ac4bd7008d9da5 546 Gene3D G3DSA:3.40.50.200 196 545 1.0E-27 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS35325 2bf0545b9c4fa367c2ac4bd7008d9da5 546 SMART SM00944 40 183 1.2E-46 T 28-03-2018 IPR015366 Peptidase S53, activation domain GO:0008236 Reactome: R-HSA-381038 CU254_RS35325 2bf0545b9c4fa367c2ac4bd7008d9da5 546 SUPERFAMILY SSF54897 39 190 7.14E-37 T 28-03-2018 IPR009020 Protease propeptides/proteinase inhibitor I9 CU254_RS35325 2bf0545b9c4fa367c2ac4bd7008d9da5 546 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 462 472 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CU254_RS35325 2bf0545b9c4fa367c2ac4bd7008d9da5 546 SUPERFAMILY SSF52743 200 541 4.58E-53 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS30055 9f0c62f4bcc9304c87c56a7f800ee0a9 1711 SUPERFAMILY SSF53901 39 400 2.13E-102 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS30055 9f0c62f4bcc9304c87c56a7f800ee0a9 1711 Pfam PF08659 KR domain 1293 1465 2.8E-55 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS30055 9f0c62f4bcc9304c87c56a7f800ee0a9 1711 Gene3D G3DSA:1.10.1200.10 1537 1636 4.4E-18 T 28-03-2018 CU254_RS30055 9f0c62f4bcc9304c87c56a7f800ee0a9 1711 Gene3D G3DSA:3.40.47.10 32 283 4.2E-81 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS30055 9f0c62f4bcc9304c87c56a7f800ee0a9 1711 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 191 207 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CU254_RS30055 9f0c62f4bcc9304c87c56a7f800ee0a9 1711 Gene3D G3DSA:3.40.47.10 293 452 2.0E-61 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS30055 9f0c62f4bcc9304c87c56a7f800ee0a9 1711 Gene3D G3DSA:3.40.366.10 710 824 5.4E-25 T 28-03-2018 CU254_RS30055 9f0c62f4bcc9304c87c56a7f800ee0a9 1711 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 536 820 1.6E-112 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CU254_RS30055 9f0c62f4bcc9304c87c56a7f800ee0a9 1711 SMART SM00825 Beta-ketoacyl synthase 44 454 1.9E-205 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CU254_RS30055 9f0c62f4bcc9304c87c56a7f800ee0a9 1711 SMART SM01294 1562 1629 6.2E-6 T 28-03-2018 CU254_RS30055 9f0c62f4bcc9304c87c56a7f800ee0a9 1711 Pfam PF00550 Phosphopantetheine attachment site 1565 1629 5.5E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS30055 9f0c62f4bcc9304c87c56a7f800ee0a9 1711 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 42 278 5.3E-83 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CU254_RS30055 9f0c62f4bcc9304c87c56a7f800ee0a9 1711 Pfam PF00698 Acyl transferase domain 535 838 3.0E-59 T 28-03-2018 IPR014043 Acyl transferase CU254_RS30055 9f0c62f4bcc9304c87c56a7f800ee0a9 1711 SUPERFAMILY SSF51735 1155 1280 2.99E-17 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS30055 9f0c62f4bcc9304c87c56a7f800ee0a9 1711 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 404 497 3.5E-13 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS30055 9f0c62f4bcc9304c87c56a7f800ee0a9 1711 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1588 1603 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CU254_RS30055 9f0c62f4bcc9304c87c56a7f800ee0a9 1711 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 286 401 1.9E-42 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CU254_RS30055 9f0c62f4bcc9304c87c56a7f800ee0a9 1711 SUPERFAMILY SSF52151 533 652 3.66E-68 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CU254_RS30055 9f0c62f4bcc9304c87c56a7f800ee0a9 1711 SUPERFAMILY SSF52151 709 817 3.66E-68 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CU254_RS30055 9f0c62f4bcc9304c87c56a7f800ee0a9 1711 Pfam PF08990 Erythronolide synthase docking 11 35 8.4E-6 T 28-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 CU254_RS30055 9f0c62f4bcc9304c87c56a7f800ee0a9 1711 Pfam PF14765 Polyketide synthase dehydratase 885 1149 3.6E-52 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS30055 9f0c62f4bcc9304c87c56a7f800ee0a9 1711 SUPERFAMILY SSF51735 1291 1536 3.97E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS30055 9f0c62f4bcc9304c87c56a7f800ee0a9 1711 Gene3D G3DSA:3.30.70.250 668 709 3.0E-15 T 28-03-2018 CU254_RS30055 9f0c62f4bcc9304c87c56a7f800ee0a9 1711 Gene3D G3DSA:3.40.50.720 1288 1527 1.8E-49 T 28-03-2018 CU254_RS30055 9f0c62f4bcc9304c87c56a7f800ee0a9 1711 SMART SM00823 Phosphopantetheine attachment site 1561 1633 1.5E-28 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS30055 9f0c62f4bcc9304c87c56a7f800ee0a9 1711 Gene3D G3DSA:3.40.366.10 532 667 1.9E-42 T 28-03-2018 CU254_RS30055 9f0c62f4bcc9304c87c56a7f800ee0a9 1711 Gene3D G3DSA:3.10.129.10 883 1001 1.0E-6 T 28-03-2018 CU254_RS30055 9f0c62f4bcc9304c87c56a7f800ee0a9 1711 SUPERFAMILY SSF55048 657 710 3.27E-9 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CU254_RS30055 9f0c62f4bcc9304c87c56a7f800ee0a9 1711 SUPERFAMILY SSF47336 1553 1639 8.11E-20 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS30055 9f0c62f4bcc9304c87c56a7f800ee0a9 1711 SMART SM00826 885 1043 8.0E-76 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS30055 9f0c62f4bcc9304c87c56a7f800ee0a9 1711 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1291 1466 7.0E-54 T 28-03-2018 CU254_RS36455 5efe46a56f46dac156b5cda705378749 723 SUPERFAMILY SSF103473 35 462 2.49E-35 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS36455 5efe46a56f46dac156b5cda705378749 723 Gene3D G3DSA:1.20.1250.20 257 467 1.5E-16 T 28-03-2018 CU254_RS36455 5efe46a56f46dac156b5cda705378749 723 Gene3D G3DSA:3.40.50.300 481 618 1.7E-21 T 28-03-2018 CU254_RS36455 5efe46a56f46dac156b5cda705378749 723 Pfam PF05977 Transmembrane secretion effector 30 420 9.8E-16 T 28-03-2018 IPR010290 Transmembrane secretion effector CU254_RS36455 5efe46a56f46dac156b5cda705378749 723 Pfam PF02223 Thymidylate kinase 499 616 2.0E-8 T 28-03-2018 CU254_RS36455 5efe46a56f46dac156b5cda705378749 723 SUPERFAMILY SSF52540 483 651 8.8E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS36455 5efe46a56f46dac156b5cda705378749 723 Hamap MF_00165 Thymidylate kinase [tmk]. 484 668 13.867 T 28-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CU254_RS36455 5efe46a56f46dac156b5cda705378749 723 Gene3D G3DSA:1.20.1250.20 18 250 2.4E-17 T 28-03-2018 CU254_RS30600 6caa504c1d132b02806374770da5a65a 290 PRINTS PR00093 Uricase signature 147 163 5.5E-17 T 28-03-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CU254_RS30600 6caa504c1d132b02806374770da5a65a 290 PRINTS PR00093 Uricase signature 163 175 5.5E-17 T 28-03-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CU254_RS30600 6caa504c1d132b02806374770da5a65a 290 PRINTS PR00093 Uricase signature 50 64 5.5E-17 T 28-03-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CU254_RS30600 6caa504c1d132b02806374770da5a65a 290 PRINTS PR00093 Uricase signature 11 22 5.5E-17 T 28-03-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CU254_RS30600 6caa504c1d132b02806374770da5a65a 290 PRINTS PR00093 Uricase signature 85 98 5.5E-17 T 28-03-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CU254_RS30600 6caa504c1d132b02806374770da5a65a 290 SUPERFAMILY SSF55620 138 289 3.5E-56 T 28-03-2018 CU254_RS30600 6caa504c1d132b02806374770da5a65a 290 SUPERFAMILY SSF55620 3 130 2.22E-41 T 28-03-2018 CU254_RS30600 6caa504c1d132b02806374770da5a65a 290 Gene3D G3DSA:3.10.270.10 1 284 3.0E-110 T 28-03-2018 CU254_RS30600 6caa504c1d132b02806374770da5a65a 290 PIRSF PIRSF000241 1 285 1.4E-95 T 28-03-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CU254_RS30600 6caa504c1d132b02806374770da5a65a 290 Pfam PF01014 Uricase 143 274 9.1E-32 T 28-03-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CU254_RS30600 6caa504c1d132b02806374770da5a65a 290 Pfam PF01014 Uricase 9 131 1.0E-15 T 28-03-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CU254_RS30600 6caa504c1d132b02806374770da5a65a 290 ProDom PD003367 URICASE OXIDOREDUCTASE URATE OXIDASE METABOLISM PURINE PEROXISOME ACETYLATION II DIRECT 177 279 1.0E-30 T 28-03-2018 CU254_RS30600 6caa504c1d132b02806374770da5a65a 290 TIGRFAM TIGR03383 urate_oxi: urate oxidase 5 279 1.5E-101 T 28-03-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CU254_RS07765 26d188c1f7faaf44b4da55abd3f43eaf 447 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 420 433 - T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CU254_RS07765 26d188c1f7faaf44b4da55abd3f43eaf 447 SMART SM00962 248 447 2.4E-101 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CU254_RS07765 26d188c1f7faaf44b4da55abd3f43eaf 447 Gene3D G3DSA:3.40.50.300 245 447 1.4E-37 T 28-03-2018 CU254_RS07765 26d188c1f7faaf44b4da55abd3f43eaf 447 Pfam PF02881 SRP54-type protein, helical bundle domain 161 223 2.9E-10 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CU254_RS07765 26d188c1f7faaf44b4da55abd3f43eaf 447 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 171 446 1.4E-104 T 28-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 CU254_RS07765 26d188c1f7faaf44b4da55abd3f43eaf 447 SMART SM00382 247 397 3.4E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS07765 26d188c1f7faaf44b4da55abd3f43eaf 447 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 170 447 57.737 T 28-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 CU254_RS07765 26d188c1f7faaf44b4da55abd3f43eaf 447 SUPERFAMILY SSF52540 246 446 1.81E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS07765 26d188c1f7faaf44b4da55abd3f43eaf 447 SMART SM00963 147 227 3.6E-19 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CU254_RS07765 26d188c1f7faaf44b4da55abd3f43eaf 447 Gene3D G3DSA:1.20.120.140 135 225 2.8E-17 T 28-03-2018 CU254_RS07765 26d188c1f7faaf44b4da55abd3f43eaf 447 SUPERFAMILY SSF47364 142 221 2.49E-18 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CU254_RS07765 26d188c1f7faaf44b4da55abd3f43eaf 447 Pfam PF00448 SRP54-type protein, GTPase domain 248 447 3.4E-72 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CU254_RS37765 78beef63fe0789ee23406ca392490dc3 173 Gene3D G3DSA:3.90.79.10 7 152 2.0E-22 T 28-03-2018 CU254_RS37765 78beef63fe0789ee23406ca392490dc3 173 Pfam PF00293 NUDIX domain 16 133 8.9E-16 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CU254_RS37765 78beef63fe0789ee23406ca392490dc3 173 SUPERFAMILY SSF55811 14 139 2.71E-22 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CU254_RS11945 0dc7bd45eb963d4df7dcdd5f5407699e 248 SUPERFAMILY SSF52540 75 201 4.5E-8 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS11945 0dc7bd45eb963d4df7dcdd5f5407699e 248 Gene3D G3DSA:3.40.50.300 55 230 1.6E-7 T 28-03-2018 CU254_RS19360 fecfaae36d1d3917337ba086a9b5c0e0 346 Pfam PF03824 High-affinity nickel-transport protein 40 326 2.0E-80 T 28-03-2018 IPR011541 Nickel/cobalt transporter, high-affinity GO:0015099|GO:0016021|GO:0035444|GO:0046872 CU254_RS19360 fecfaae36d1d3917337ba086a9b5c0e0 346 TIGRFAM TIGR00802 nico: transition metal uptake transporter, Ni2+-Co2+ transporter (NiCoT) family 42 322 1.9E-111 T 28-03-2018 IPR004688 Transition metal uptake transporter nickel/cobalt GO:0015099|GO:0016021|GO:0035444|GO:0046872 CU254_RS19375 0d4d6b4a3dd895b6ef5d40810fe1ef85 1185 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 196 212 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CU254_RS19375 0d4d6b4a3dd895b6ef5d40810fe1ef85 1185 SMART SM00824 Thioesterase 975 1181 7.7E-62 T 28-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 CU254_RS19375 0d4d6b4a3dd895b6ef5d40810fe1ef85 1185 Pfam PF00698 Acyl transferase domain 572 674 2.1E-9 T 28-03-2018 IPR014043 Acyl transferase CU254_RS19375 0d4d6b4a3dd895b6ef5d40810fe1ef85 1185 Gene3D G3DSA:3.40.47.10 299 458 1.3E-58 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS19375 0d4d6b4a3dd895b6ef5d40810fe1ef85 1185 Gene3D G3DSA:3.40.50.1820 918 1185 3.7E-20 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS19375 0d4d6b4a3dd895b6ef5d40810fe1ef85 1185 Gene3D G3DSA:1.10.1200.10 805 907 1.2E-6 T 28-03-2018 CU254_RS19375 0d4d6b4a3dd895b6ef5d40810fe1ef85 1185 SUPERFAMILY SSF53901 29 403 2.89E-93 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS19375 0d4d6b4a3dd895b6ef5d40810fe1ef85 1185 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 409 528 1.9E-16 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS19375 0d4d6b4a3dd895b6ef5d40810fe1ef85 1185 SUPERFAMILY SSF53474 866 903 1.42E-30 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS19375 0d4d6b4a3dd895b6ef5d40810fe1ef85 1185 SUPERFAMILY SSF53474 950 1183 1.42E-30 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS19375 0d4d6b4a3dd895b6ef5d40810fe1ef85 1185 Gene3D G3DSA:3.40.366.10 552 783 2.3E-21 T 28-03-2018 CU254_RS19375 0d4d6b4a3dd895b6ef5d40810fe1ef85 1185 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 292 406 7.4E-41 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CU254_RS19375 0d4d6b4a3dd895b6ef5d40810fe1ef85 1185 SMART SM00825 Beta-ketoacyl synthase 36 460 1.1E-190 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CU254_RS19375 0d4d6b4a3dd895b6ef5d40810fe1ef85 1185 Pfam PF00975 Thioesterase domain 988 1083 1.1E-17 T 28-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CU254_RS19375 0d4d6b4a3dd895b6ef5d40810fe1ef85 1185 Gene3D G3DSA:3.40.47.10 26 295 9.8E-80 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS19375 0d4d6b4a3dd895b6ef5d40810fe1ef85 1185 SMART SM00823 Phosphopantetheine attachment site 836 907 0.0038 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS19375 0d4d6b4a3dd895b6ef5d40810fe1ef85 1185 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 283 2.6E-86 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CU254_RS19375 0d4d6b4a3dd895b6ef5d40810fe1ef85 1185 SUPERFAMILY SSF52151 571 679 1.26E-13 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CU254_RS21980 3cf06c4d1728ad8011131436a305abcd 659 Gene3D G3DSA:2.60.40.1180 564 659 2.3E-35 T 28-03-2018 CU254_RS21980 3cf06c4d1728ad8011131436a305abcd 659 Gene3D G3DSA:3.20.20.80 194 563 4.1E-62 T 28-03-2018 CU254_RS21980 3cf06c4d1728ad8011131436a305abcd 659 Hamap MF_02124 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase [glgE]. 1 655 45.084 T 28-03-2018 IPR026585 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase GO:0016757 KEGG: 00500+2.4.99.16 CU254_RS21980 3cf06c4d1728ad8011131436a305abcd 659 Gene3D G3DSA:2.60.40.10 1 100 1.1E-40 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS21980 3cf06c4d1728ad8011131436a305abcd 659 Pfam PF00128 Alpha amylase, catalytic domain 229 314 1.2E-4 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CU254_RS21980 3cf06c4d1728ad8011131436a305abcd 659 Gene3D G3DSA:1.20.58.280 101 174 6.0E-23 T 28-03-2018 CU254_RS21980 3cf06c4d1728ad8011131436a305abcd 659 SUPERFAMILY SSF51445 192 560 8.96E-82 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS21980 3cf06c4d1728ad8011131436a305abcd 659 SMART SM00642 199 534 1.4E-4 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CU254_RS21980 3cf06c4d1728ad8011131436a305abcd 659 Pfam PF11896 Domain of unknown function (DUF3416) 3 193 1.2E-57 T 28-03-2018 IPR021828 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase, domain N/S GO:0004553 KEGG: 00500+2.4.99.16 CU254_RS35210 5a83d283021e5df844c30e1d3ce1671c 268 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 52 261 5.0E-40 T 28-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 CU254_RS35210 5a83d283021e5df844c30e1d3ce1671c 268 Gene3D G3DSA:3.40.190.10 218 264 0.0024 T 28-03-2018 CU254_RS35210 5a83d283021e5df844c30e1d3ce1671c 268 Gene3D G3DSA:3.40.190.10 137 217 5.7E-23 T 28-03-2018 CU254_RS35210 5a83d283021e5df844c30e1d3ce1671c 268 PIRSF PIRSF004846 1 268 4.8E-64 T 28-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 CU254_RS35210 5a83d283021e5df844c30e1d3ce1671c 268 Pfam PF13531 Bacterial extracellular solute-binding protein 47 264 4.1E-43 T 28-03-2018 CU254_RS35210 5a83d283021e5df844c30e1d3ce1671c 268 Gene3D G3DSA:3.40.190.10 1 136 4.4E-27 T 28-03-2018 CU254_RS35210 5a83d283021e5df844c30e1d3ce1671c 268 SUPERFAMILY SSF53850 46 265 9.4E-56 T 28-03-2018 CU254_RS23885 19fb0a5f228d2e484af9751ab9f570fe 536 Gene3D G3DSA:3.30.300.30 437 535 1.5E-24 T 28-03-2018 CU254_RS23885 19fb0a5f228d2e484af9751ab9f570fe 536 Gene3D G3DSA:3.40.50.980 192 350 1.6E-39 T 28-03-2018 CU254_RS23885 19fb0a5f228d2e484af9751ab9f570fe 536 SUPERFAMILY SSF56801 41 534 6.15E-140 T 28-03-2018 CU254_RS23885 19fb0a5f228d2e484af9751ab9f570fe 536 Gene3D G3DSA:3.40.50.980 35 191 7.5E-38 T 28-03-2018 CU254_RS23885 19fb0a5f228d2e484af9751ab9f570fe 536 Pfam PF00501 AMP-binding enzyme 46 441 1.8E-92 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS23885 19fb0a5f228d2e484af9751ab9f570fe 536 Pfam PF13193 AMP-binding enzyme C-terminal domain 451 527 2.2E-15 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS23885 19fb0a5f228d2e484af9751ab9f570fe 536 ProSitePatterns PS00455 Putative AMP-binding domain signature. 186 197 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS23885 19fb0a5f228d2e484af9751ab9f570fe 536 Gene3D G3DSA:2.30.38.10 351 435 2.1E-29 T 28-03-2018 CU254_RS37180 e2ae63004f44d9d30ddc95b6abf457a6 324 SUPERFAMILY SSF53686 7 313 5.24E-73 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CU254_RS37180 e2ae63004f44d9d30ddc95b6abf457a6 324 Gene3D G3DSA:3.40.50.1100 31 136 2.1E-23 T 28-03-2018 CU254_RS37180 e2ae63004f44d9d30ddc95b6abf457a6 324 Gene3D G3DSA:3.40.50.1100 137 310 6.0E-37 T 28-03-2018 CU254_RS37180 e2ae63004f44d9d30ddc95b6abf457a6 324 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 20 304 4.1E-70 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CU254_RS09230 ea92b21fcae7507f6a4c5d7abc9572fd 232 SUPERFAMILY SSF52518 26 224 2.41E-48 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS09230 ea92b21fcae7507f6a4c5d7abc9572fd 232 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 26 211 9.4E-26 T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CU254_RS09230 ea92b21fcae7507f6a4c5d7abc9572fd 232 Gene3D G3DSA:3.40.50.970 22 230 4.4E-39 T 28-03-2018 CU254_RS24140 bafacf0df8ebe0098d9fa852d86dc7d7 281 Pfam PF00775 Dioxygenase 104 278 2.5E-60 T 28-03-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 CU254_RS24140 bafacf0df8ebe0098d9fa852d86dc7d7 281 TIGRFAM TIGR02438 catachol_actin: catechol 1,2-dioxygenase 2 279 2.9E-148 T 28-03-2018 IPR012800 Catechol 1,2-dioxygenase, actinobacteria KEGG: 00361+1.13.11.1|KEGG: 00362+1.13.11.1|KEGG: 00364+1.13.11.1|KEGG: 00623+1.13.11.1 CU254_RS24140 bafacf0df8ebe0098d9fa852d86dc7d7 281 Pfam PF04444 Catechol dioxygenase N terminus 34 100 3.0E-18 T 28-03-2018 IPR007535 Catechol dioxygenase, N-terminal GO:0005506|GO:0009712|GO:0018576|GO:0055114 CU254_RS24140 bafacf0df8ebe0098d9fa852d86dc7d7 281 Gene3D G3DSA:2.60.130.10 6 280 6.3E-63 T 28-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 CU254_RS24140 bafacf0df8ebe0098d9fa852d86dc7d7 281 SUPERFAMILY SSF49482 27 279 6.02E-80 T 28-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 CU254_RS07055 15c265e037d7d394320a8dd5b9edde78 341 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 187 327 1.9E-51 T 28-03-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CU254_RS07055 15c265e037d7d394320a8dd5b9edde78 341 SUPERFAMILY SSF48179 186 339 3.63E-53 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CU254_RS07055 15c265e037d7d394320a8dd5b9edde78 341 Gene3D G3DSA:1.10.1040.10 187 338 2.0E-52 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CU254_RS07055 15c265e037d7d394320a8dd5b9edde78 341 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 13 30 9.2E-46 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CU254_RS07055 15c265e037d7d394320a8dd5b9edde78 341 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 205 229 9.2E-46 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CU254_RS07055 15c265e037d7d394320a8dd5b9edde78 341 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 245 262 9.2E-46 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CU254_RS07055 15c265e037d7d394320a8dd5b9edde78 341 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 180 204 9.2E-46 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CU254_RS07055 15c265e037d7d394320a8dd5b9edde78 341 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 63 90 9.2E-46 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CU254_RS07055 15c265e037d7d394320a8dd5b9edde78 341 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 140 160 9.2E-46 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CU254_RS07055 15c265e037d7d394320a8dd5b9edde78 341 Gene3D G3DSA:3.40.50.720 4 186 3.3E-46 T 28-03-2018 CU254_RS07055 15c265e037d7d394320a8dd5b9edde78 341 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 9 330 37.6 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CU254_RS07055 15c265e037d7d394320a8dd5b9edde78 341 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 195 216 - T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CU254_RS07055 15c265e037d7d394320a8dd5b9edde78 341 PIRSF PIRSF000114 5 339 8.7E-105 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CU254_RS07055 15c265e037d7d394320a8dd5b9edde78 341 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 11 167 9.1E-53 T 28-03-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CU254_RS07055 15c265e037d7d394320a8dd5b9edde78 341 SUPERFAMILY SSF51735 10 186 6.11E-53 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS29690 4e2d2e49f0dbb2845dcd43db8f28cfce 1261 Gene3D G3DSA:3.30.200.20 270 368 1.7E-11 T 28-03-2018 CU254_RS29690 4e2d2e49f0dbb2845dcd43db8f28cfce 1261 Pfam PF00069 Protein kinase domain 285 477 1.1E-25 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CU254_RS29690 4e2d2e49f0dbb2845dcd43db8f28cfce 1261 Pfam PF16918 Protein kinase G tetratricopeptide repeat 590 755 3.7E-28 T 28-03-2018 IPR031636 Protein kinase G, tetratricopeptide repeat containing domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CU254_RS29690 4e2d2e49f0dbb2845dcd43db8f28cfce 1261 Gene3D G3DSA:1.25.40.10 576 701 2.2E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS29690 4e2d2e49f0dbb2845dcd43db8f28cfce 1261 SMART SM00220 279 538 1.9E-13 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CU254_RS29690 4e2d2e49f0dbb2845dcd43db8f28cfce 1261 SUPERFAMILY SSF48452 580 688 6.7E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS29690 4e2d2e49f0dbb2845dcd43db8f28cfce 1261 Pfam PF16919 Protein kinase G rubredoxin domain 207 277 7.9E-22 T 28-03-2018 IPR031634 Protein kinase G, rubredoxin domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CU254_RS29690 4e2d2e49f0dbb2845dcd43db8f28cfce 1261 SUPERFAMILY SSF56112 266 495 2.73E-41 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS29690 4e2d2e49f0dbb2845dcd43db8f28cfce 1261 Gene3D G3DSA:1.10.510.10 369 542 3.2E-25 T 28-03-2018 CU254_RS29690 4e2d2e49f0dbb2845dcd43db8f28cfce 1261 SUPERFAMILY SSF50494 14 154 1.28E-7 T 28-03-2018 IPR009003 Peptidase S1, PA clan CU254_RS39820 0202a9175ed2cb4cb4dc0b4c9aaaeab6 297 Gene3D G3DSA:3.10.180.10 184 297 2.1E-12 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS39820 0202a9175ed2cb4cb4dc0b4c9aaaeab6 297 SUPERFAMILY SSF54593 190 295 7.38E-15 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS39820 0202a9175ed2cb4cb4dc0b4c9aaaeab6 297 Gene3D G3DSA:3.10.180.10 49 183 6.8E-25 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS39820 0202a9175ed2cb4cb4dc0b4c9aaaeab6 297 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 58 167 2.9E-7 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CU254_RS39820 0202a9175ed2cb4cb4dc0b4c9aaaeab6 297 SUPERFAMILY SSF54593 54 171 2.62E-22 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS22635 5c18e5bbb745c04d2a4bf0a4bd56d36c 276 SUPERFAMILY SSF103032 46 275 3.92E-29 T 28-03-2018 IPR015315 Protein of unknown function DUF1963 CU254_RS22635 5c18e5bbb745c04d2a4bf0a4bd56d36c 276 Pfam PF09234 Domain of unknown function (DUF1963) 46 274 6.8E-31 T 28-03-2018 IPR015315 Protein of unknown function DUF1963 CU254_RS22635 5c18e5bbb745c04d2a4bf0a4bd56d36c 276 Gene3D G3DSA:2.30.320.10 12 276 4.0E-51 T 28-03-2018 CU254_RS25955 e7fef7bba1a159b01812c754d1547af3 84 SUPERFAMILY SSF56349 2 58 1.0E-5 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CU254_RS25955 e7fef7bba1a159b01812c754d1547af3 84 Gene3D G3DSA:1.10.443.10 1 73 8.7E-7 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CU254_RS31015 1e7739a9f4a29f2adff543045353ba63 434 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 143 312 2.6E-7 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CU254_RS31015 1e7739a9f4a29f2adff543045353ba63 434 PIRSF PIRSF000484 4 427 8.8E-99 T 28-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 CU254_RS31015 1e7739a9f4a29f2adff543045353ba63 434 SUPERFAMILY SSF54675 11 141 7.46E-42 T 28-03-2018 CU254_RS31015 1e7739a9f4a29f2adff543045353ba63 434 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 13 373 1.8E-132 T 28-03-2018 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264|Reactome: R-HSA-6798695 CU254_RS31015 1e7739a9f4a29f2adff543045353ba63 434 SUPERFAMILY SSF51690 143 430 1.83E-83 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CU254_RS31015 1e7739a9f4a29f2adff543045353ba63 434 Gene3D G3DSA:3.20.140.10 5 372 3.0E-101 T 28-03-2018 CU254_RS01495 92d1d7204a00ec542b1a7190b44ffd3c 436 PIRSF PIRSF000124 4 434 4.1E-122 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CU254_RS01495 92d1d7204a00ec542b1a7190b44ffd3c 436 SUPERFAMILY SSF48179 198 295 1.34E-30 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CU254_RS01495 92d1d7204a00ec542b1a7190b44ffd3c 436 SMART SM00984 317 419 1.9E-39 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CU254_RS01495 92d1d7204a00ec542b1a7190b44ffd3c 436 SUPERFAMILY SSF51735 4 192 4.42E-48 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS01495 92d1d7204a00ec542b1a7190b44ffd3c 436 Gene3D G3DSA:1.20.5.100 198 220 3.9E-12 T 28-03-2018 CU254_RS01495 92d1d7204a00ec542b1a7190b44ffd3c 436 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 318 418 5.3E-29 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CU254_RS01495 92d1d7204a00ec542b1a7190b44ffd3c 436 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 5 415 1.4E-124 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CU254_RS01495 92d1d7204a00ec542b1a7190b44ffd3c 436 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 5 180 1.5E-53 T 28-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CU254_RS01495 92d1d7204a00ec542b1a7190b44ffd3c 436 PIRSF PIRSF500134 4 436 1.4E-146 T 28-03-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 CU254_RS01495 92d1d7204a00ec542b1a7190b44ffd3c 436 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 198 289 2.0E-33 T 28-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CU254_RS01495 92d1d7204a00ec542b1a7190b44ffd3c 436 Gene3D G3DSA:3.40.50.720 221 430 7.2E-64 T 28-03-2018 CU254_RS01495 92d1d7204a00ec542b1a7190b44ffd3c 436 SUPERFAMILY SSF52413 308 428 7.46E-30 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CU254_RS01495 92d1d7204a00ec542b1a7190b44ffd3c 436 Gene3D G3DSA:3.40.50.720 3 193 7.8E-54 T 28-03-2018 CU254_RS15555 e1a7689ab513a261f950de3456448be9 352 SUPERFAMILY SSF102114 21 322 2.22E-71 T 28-03-2018 CU254_RS15555 e1a7689ab513a261f950de3456448be9 352 Gene3D G3DSA:3.20.20.70 16 326 1.1E-49 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS15555 e1a7689ab513a261f950de3456448be9 352 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 233 322 3.5E-14 T 28-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CU254_RS15555 e1a7689ab513a261f950de3456448be9 352 PIRSF PIRSF001619 2 330 2.0E-107 T 28-03-2018 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CU254_RS15555 e1a7689ab513a261f950de3456448be9 352 SMART SM00729 56 265 2.8E-34 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CU254_RS15555 e1a7689ab513a261f950de3456448be9 352 TIGRFAM TIGR00433 bioB: biotin synthase 28 322 4.7E-114 T 28-03-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CU254_RS15555 e1a7689ab513a261f950de3456448be9 352 Hamap MF_01694 Biotin synthase [bioB]. 16 324 39.567 T 28-03-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CU254_RS15555 e1a7689ab513a261f950de3456448be9 352 SMART SM00876 233 323 5.9E-32 T 28-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CU254_RS15555 e1a7689ab513a261f950de3456448be9 352 Pfam PF04055 Radical SAM superfamily 66 221 3.7E-16 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CU254_RS34320 56f91b668adb0b35a576b1ccc3700adf 246 Gene3D G3DSA:3.40.50.300 2 245 2.2E-42 T 28-03-2018 CU254_RS34320 56f91b668adb0b35a576b1ccc3700adf 246 Pfam PF00005 ABC transporter 47 177 1.3E-19 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS34320 56f91b668adb0b35a576b1ccc3700adf 246 SMART SM00382 56 228 7.1E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS34320 56f91b668adb0b35a576b1ccc3700adf 246 SUPERFAMILY SSF52540 45 241 3.13E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS34320 56f91b668adb0b35a576b1ccc3700adf 246 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS20930 c1d2794821dfec51a49f5ec8b6f8c44b 324 Pfam PF00107 Zinc-binding dehydrogenase 165 286 3.9E-27 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CU254_RS20930 c1d2794821dfec51a49f5ec8b6f8c44b 324 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 24 121 5.1E-11 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CU254_RS20930 c1d2794821dfec51a49f5ec8b6f8c44b 324 SUPERFAMILY SSF51735 126 291 1.31E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS20930 c1d2794821dfec51a49f5ec8b6f8c44b 324 SUPERFAMILY SSF50129 8 159 1.22E-35 T 28-03-2018 IPR011032 GroES-like CU254_RS20930 c1d2794821dfec51a49f5ec8b6f8c44b 324 Gene3D G3DSA:3.90.180.10 2 324 5.7E-72 T 28-03-2018 CU254_RS20930 c1d2794821dfec51a49f5ec8b6f8c44b 324 SMART SM00829 8 321 7.2E-20 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CU254_RS27255 18a2d7c95b08dd4ebe11adc147ba5ace 296 SUPERFAMILY SSF47413 34 85 1.72E-6 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS27255 18a2d7c95b08dd4ebe11adc147ba5ace 296 Gene3D G3DSA:1.10.260.40 5 104 4.2E-11 T 28-03-2018 CU254_RS27255 18a2d7c95b08dd4ebe11adc147ba5ace 296 Pfam PF13560 Helix-turn-helix domain 34 88 1.4E-13 T 28-03-2018 CU254_RS27255 18a2d7c95b08dd4ebe11adc147ba5ace 296 SMART SM00530 10 86 4.3E-5 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS18870 1a3ff4746247df90ee93d8484e6c5ef0 382 SUPERFAMILY SSF82171 33 375 4.32E-16 T 28-03-2018 CU254_RS18870 1a3ff4746247df90ee93d8484e6c5ef0 382 Gene3D G3DSA:2.140.10.30 18 203 5.1E-9 T 28-03-2018 CU254_RS18870 1a3ff4746247df90ee93d8484e6c5ef0 382 Gene3D G3DSA:2.130.10.120 264 377 0.0012 T 28-03-2018 CU254_RS17400 750b0eb280913b144ec5a03c8836c247 338 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 10 326 2.4E-77 T 28-03-2018 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 CU254_RS17400 750b0eb280913b144ec5a03c8836c247 338 SUPERFAMILY SSF51556 6 332 1.92E-70 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS17400 750b0eb280913b144ec5a03c8836c247 338 ProSitePatterns PS00485 Adenosine and AMP deaminase signature. 273 279 - T 28-03-2018 IPR006650 Adenosine/AMP deaminase active site GO:0009168|GO:0019239 Reactome: R-HSA-74217 CU254_RS17400 750b0eb280913b144ec5a03c8836c247 338 Pfam PF00962 Adenosine/AMP deaminase 10 327 2.6E-62 T 28-03-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 CU254_RS17400 750b0eb280913b144ec5a03c8836c247 338 Gene3D G3DSA:3.20.20.140 2 335 2.0E-74 T 28-03-2018 CU254_RS37335 e4e6e2d2dd7eceacc38b08571ce4f62f 444 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 59 313 5.9E-62 T 28-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 CU254_RS37335 e4e6e2d2dd7eceacc38b08571ce4f62f 444 PRINTS PR01181 Diaminopimelate decarboxylase signature 412 434 5.8E-22 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CU254_RS37335 e4e6e2d2dd7eceacc38b08571ce4f62f 444 PRINTS PR01181 Diaminopimelate decarboxylase signature 330 348 5.8E-22 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CU254_RS37335 e4e6e2d2dd7eceacc38b08571ce4f62f 444 PRINTS PR01181 Diaminopimelate decarboxylase signature 183 192 5.8E-22 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CU254_RS37335 e4e6e2d2dd7eceacc38b08571ce4f62f 444 PRINTS PR01181 Diaminopimelate decarboxylase signature 97 114 5.8E-22 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CU254_RS37335 e4e6e2d2dd7eceacc38b08571ce4f62f 444 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 32 442 1.6E-122 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CU254_RS37335 e4e6e2d2dd7eceacc38b08571ce4f62f 444 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 39 444 36.65 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CU254_RS37335 e4e6e2d2dd7eceacc38b08571ce4f62f 444 SUPERFAMILY SSF51419 50 315 2.04E-69 T 28-03-2018 IPR029066 PLP-binding barrel CU254_RS37335 e4e6e2d2dd7eceacc38b08571ce4f62f 444 Gene3D G3DSA:2.40.37.10 301 444 1.1E-38 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CU254_RS37335 e4e6e2d2dd7eceacc38b08571ce4f62f 444 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 277 402 6.2E-18 T 28-03-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 CU254_RS37335 e4e6e2d2dd7eceacc38b08571ce4f62f 444 SUPERFAMILY SSF50621 293 442 1.17E-45 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CU254_RS37335 e4e6e2d2dd7eceacc38b08571ce4f62f 444 Gene3D G3DSA:3.20.20.10 58 300 3.3E-63 T 28-03-2018 IPR029066 PLP-binding barrel CU254_RS37335 e4e6e2d2dd7eceacc38b08571ce4f62f 444 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 79 97 6.6E-18 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CU254_RS37335 e4e6e2d2dd7eceacc38b08571ce4f62f 444 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 303 322 6.6E-18 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CU254_RS37335 e4e6e2d2dd7eceacc38b08571ce4f62f 444 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 99 111 6.6E-18 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CU254_RS37335 e4e6e2d2dd7eceacc38b08571ce4f62f 444 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 402 415 6.6E-18 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CU254_RS37335 e4e6e2d2dd7eceacc38b08571ce4f62f 444 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 214 227 6.6E-18 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CU254_RS37335 e4e6e2d2dd7eceacc38b08571ce4f62f 444 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 79 97 - T 28-03-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site CU254_RS29180 b8120b93be9bcfe4516053eed625444b 156 Gene3D G3DSA:3.90.79.10 1 150 4.0E-31 T 28-03-2018 CU254_RS29180 b8120b93be9bcfe4516053eed625444b 156 PRINTS PR00502 NUDIX hydrolase family signature 57 72 3.7E-7 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CU254_RS29180 b8120b93be9bcfe4516053eed625444b 156 PRINTS PR00502 NUDIX hydrolase family signature 43 57 3.7E-7 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CU254_RS29180 b8120b93be9bcfe4516053eed625444b 156 SUPERFAMILY SSF55811 1 149 1.33E-32 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CU254_RS29180 b8120b93be9bcfe4516053eed625444b 156 Pfam PF00293 NUDIX domain 20 143 1.6E-21 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CU254_RS40855 38b87d980b5af6a7c245c6808c2c48b2 187 SUPERFAMILY SSF46689 4 71 4.81E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS40855 38b87d980b5af6a7c245c6808c2c48b2 187 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 53 1.2E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS40855 38b87d980b5af6a7c245c6808c2c48b2 187 Gene3D G3DSA:1.10.357.10 52 186 1.4E-12 T 28-03-2018 CU254_RS40855 38b87d980b5af6a7c245c6808c2c48b2 187 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 51 8.6E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS40855 38b87d980b5af6a7c245c6808c2c48b2 187 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 7 20 8.6E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS40855 38b87d980b5af6a7c245c6808c2c48b2 187 Gene3D G3DSA:1.10.10.60 2 51 3.7E-16 T 28-03-2018 CU254_RS00220 130e0b20e66e572e5d2d9c4c1d4b53fb 147 Pfam PF01047 MarR family 36 89 1.0E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS00220 130e0b20e66e572e5d2d9c4c1d4b53fb 147 SUPERFAMILY SSF46785 11 137 4.93E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS00220 130e0b20e66e572e5d2d9c4c1d4b53fb 147 SMART SM00347 24 123 1.2E-16 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS00220 130e0b20e66e572e5d2d9c4c1d4b53fb 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 65 80 1.6E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS00220 130e0b20e66e572e5d2d9c4c1d4b53fb 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 84 100 1.6E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS00220 130e0b20e66e572e5d2d9c4c1d4b53fb 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 48 64 1.6E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS00220 130e0b20e66e572e5d2d9c4c1d4b53fb 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 113 133 1.6E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS00220 130e0b20e66e572e5d2d9c4c1d4b53fb 147 Gene3D G3DSA:1.10.10.10 3 143 7.0E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS21430 b391124f33679420c64f63fee715eeec 262 Pfam PF00378 Enoyl-CoA hydratase/isomerase 12 260 8.9E-50 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CU254_RS21430 b391124f33679420c64f63fee715eeec 262 SUPERFAMILY SSF52096 4 260 1.42E-71 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS21430 b391124f33679420c64f63fee715eeec 262 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 104 124 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CU254_RS21430 b391124f33679420c64f63fee715eeec 262 Gene3D G3DSA:1.10.12.10 221 262 2.3E-8 T 28-03-2018 IPR014748 Crontonase, C-terminal CU254_RS21430 b391124f33679420c64f63fee715eeec 262 Gene3D G3DSA:3.90.226.10 7 220 7.3E-59 T 28-03-2018 CU254_RS21235 ed6de016ebab8f863e006b5e8dd0cba7 329 Pfam PF01068 ATP dependent DNA ligase domain 29 200 4.6E-27 T 28-03-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 CU254_RS21235 ed6de016ebab8f863e006b5e8dd0cba7 329 SUPERFAMILY SSF56091 9 200 3.45E-41 T 28-03-2018 CU254_RS21235 ed6de016ebab8f863e006b5e8dd0cba7 329 Pfam PF04679 ATP dependent DNA ligase C terminal region 221 318 6.7E-24 T 28-03-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 CU254_RS21235 ed6de016ebab8f863e006b5e8dd0cba7 329 Gene3D G3DSA:3.30.1490.70 135 200 3.9E-11 T 28-03-2018 CU254_RS21235 ed6de016ebab8f863e006b5e8dd0cba7 329 TIGRFAM TIGR02779 NHEJ_ligase_lig: DNA ligase D, ligase domain 26 325 4.6E-72 T 28-03-2018 IPR014146 DNA ligase D, ligase domain CU254_RS21235 ed6de016ebab8f863e006b5e8dd0cba7 329 Gene3D G3DSA:2.40.50.140 204 327 3.1E-28 T 28-03-2018 CU254_RS21235 ed6de016ebab8f863e006b5e8dd0cba7 329 SUPERFAMILY SSF50249 205 325 1.88E-27 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CU254_RS21235 ed6de016ebab8f863e006b5e8dd0cba7 329 Gene3D G3DSA:3.30.470.30 2 134 9.2E-32 T 28-03-2018 CU254_RS22190 a1d5c408968eaf7e14d86bc2c704903c 265 SMART SM00346 17 107 4.2E-14 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS22190 a1d5c408968eaf7e14d86bc2c704903c 265 Gene3D G3DSA:1.10.10.10 1 78 4.0E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS22190 a1d5c408968eaf7e14d86bc2c704903c 265 SUPERFAMILY SSF55781 88 259 3.66E-42 T 28-03-2018 IPR029016 GAF domain-like CU254_RS22190 a1d5c408968eaf7e14d86bc2c704903c 265 Pfam PF09339 IclR helix-turn-helix domain 19 69 9.8E-12 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS22190 a1d5c408968eaf7e14d86bc2c704903c 265 Gene3D G3DSA:3.30.450.40 82 261 3.1E-44 T 28-03-2018 IPR029016 GAF domain-like CU254_RS22190 a1d5c408968eaf7e14d86bc2c704903c 265 Pfam PF01614 Bacterial transcriptional regulator 138 255 2.3E-27 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal CU254_RS22190 a1d5c408968eaf7e14d86bc2c704903c 265 SUPERFAMILY SSF46785 17 90 1.99E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS29800 8b5e8873692f971f27e946bd636cd29a 142 Pfam PF13463 Winged helix DNA-binding domain 34 97 1.4E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS29800 8b5e8873692f971f27e946bd636cd29a 142 Gene3D G3DSA:1.10.10.10 2 108 3.5E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS29800 8b5e8873692f971f27e946bd636cd29a 142 Gene3D G3DSA:1.10.287.100 109 140 1.8E-12 T 28-03-2018 CU254_RS29800 8b5e8873692f971f27e946bd636cd29a 142 SUPERFAMILY SSF46785 5 133 2.69E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS29800 8b5e8873692f971f27e946bd636cd29a 142 SMART SM00347 24 125 2.2E-15 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS33185 d6dd538bba320cfee95f632c47af3287 326 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 322 3.5E-13 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS33185 d6dd538bba320cfee95f632c47af3287 326 SUPERFAMILY SSF161098 80 313 2.88E-60 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS33185 d6dd538bba320cfee95f632c47af3287 326 Gene3D G3DSA:1.10.3720.10 37 326 4.0E-52 T 28-03-2018 CU254_RS28055 47a028bf2d79133795ba8735c8d1b131 421 Pfam PF00512 His Kinase A (phospho-acceptor) domain 224 283 1.0E-8 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS28055 47a028bf2d79133795ba8735c8d1b131 421 SMART SM00388 222 286 3.1E-9 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS28055 47a028bf2d79133795ba8735c8d1b131 421 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 326 417 1.3E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS28055 47a028bf2d79133795ba8735c8d1b131 421 SMART SM00304 169 221 2.1E-5 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS28055 47a028bf2d79133795ba8735c8d1b131 421 Gene3D G3DSA:3.30.565.10 270 417 1.2E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS28055 47a028bf2d79133795ba8735c8d1b131 421 Gene3D G3DSA:1.10.287.130 213 269 1.9E-9 T 28-03-2018 CU254_RS28055 47a028bf2d79133795ba8735c8d1b131 421 SUPERFAMILY SSF47384 208 283 1.55E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS28055 47a028bf2d79133795ba8735c8d1b131 421 SMART SM00387 323 419 5.7E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS28055 47a028bf2d79133795ba8735c8d1b131 421 SUPERFAMILY SSF55874 290 418 4.32E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS15690 913c0a506a5d7154b499f64ecc28897c 284 Gene3D G3DSA:3.40.190.10 87 170 2.0E-10 T 28-03-2018 CU254_RS15690 913c0a506a5d7154b499f64ecc28897c 284 SUPERFAMILY SSF46785 4 85 2.48E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS15690 913c0a506a5d7154b499f64ecc28897c 284 Gene3D G3DSA:3.40.190.10 171 256 2.9E-9 T 28-03-2018 CU254_RS15690 913c0a506a5d7154b499f64ecc28897c 284 Pfam PF03466 LysR substrate binding domain 90 278 6.9E-19 T 28-03-2018 IPR005119 LysR, substrate-binding CU254_RS15690 913c0a506a5d7154b499f64ecc28897c 284 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 4.6E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS15690 913c0a506a5d7154b499f64ecc28897c 284 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 4.6E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS15690 913c0a506a5d7154b499f64ecc28897c 284 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 4.6E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS15690 913c0a506a5d7154b499f64ecc28897c 284 Gene3D G3DSA:1.10.10.10 1 85 7.2E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS15690 913c0a506a5d7154b499f64ecc28897c 284 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 4.8E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS15690 913c0a506a5d7154b499f64ecc28897c 284 SUPERFAMILY SSF53850 90 280 3.08E-19 T 28-03-2018 CU254_RS37815 85bb551fbcecdde9e9712c082494569c 236 Gene3D G3DSA:1.10.10.10 2 73 2.2E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS37815 85bb551fbcecdde9e9712c082494569c 236 SMART SM00895 100 220 2.3E-22 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS37815 85bb551fbcecdde9e9712c082494569c 236 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 71 1.5E-12 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS37815 85bb551fbcecdde9e9712c082494569c 236 SUPERFAMILY SSF46785 5 75 2.04E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS37815 85bb551fbcecdde9e9712c082494569c 236 SUPERFAMILY SSF48008 99 222 2.25E-23 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS37815 85bb551fbcecdde9e9712c082494569c 236 Pfam PF07729 FCD domain 100 219 1.4E-22 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS37815 85bb551fbcecdde9e9712c082494569c 236 Gene3D G3DSA:1.20.120.530 94 231 2.8E-25 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS37815 85bb551fbcecdde9e9712c082494569c 236 SMART SM00345 13 71 7.7E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS25705 8ba8ae4bd406524c57b4e8d0a3f611ee 753 Gene3D G3DSA:3.40.50.300 492 526 4.1E-4 T 28-03-2018 CU254_RS25705 8ba8ae4bd406524c57b4e8d0a3f611ee 753 Gene3D G3DSA:3.40.50.300 634 732 2.2E-27 T 28-03-2018 CU254_RS25705 8ba8ae4bd406524c57b4e8d0a3f611ee 753 SMART SM00382 479 734 0.011 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS25705 8ba8ae4bd406524c57b4e8d0a3f611ee 753 SMART SM00382 28 416 1.4 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS25705 8ba8ae4bd406524c57b4e8d0a3f611ee 753 Pfam PF00005 ABC transporter 470 673 5.5E-10 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS25705 8ba8ae4bd406524c57b4e8d0a3f611ee 753 Gene3D G3DSA:3.40.50.300 328 446 1.6E-17 T 28-03-2018 CU254_RS25705 8ba8ae4bd406524c57b4e8d0a3f611ee 753 Gene3D G3DSA:1.20.1580.10 527 633 2.6E-20 T 28-03-2018 CU254_RS25705 8ba8ae4bd406524c57b4e8d0a3f611ee 753 Gene3D G3DSA:1.20.1580.10 95 327 7.5E-40 T 28-03-2018 CU254_RS25705 8ba8ae4bd406524c57b4e8d0a3f611ee 753 SUPERFAMILY SSF52540 276 421 9.34E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS25705 8ba8ae4bd406524c57b4e8d0a3f611ee 753 SUPERFAMILY SSF52540 9 57 9.34E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS25705 8ba8ae4bd406524c57b4e8d0a3f611ee 753 Gene3D G3DSA:3.40.50.300 4 93 3.2E-5 T 28-03-2018 CU254_RS25705 8ba8ae4bd406524c57b4e8d0a3f611ee 753 ProSitePatterns PS00211 ABC transporters family signature. 645 659 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS25705 8ba8ae4bd406524c57b4e8d0a3f611ee 753 SUPERFAMILY SSF52540 469 739 3.95E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS25705 8ba8ae4bd406524c57b4e8d0a3f611ee 753 Gene3D G3DSA:3.40.50.300 461 491 8.3E-5 T 28-03-2018 CU254_RS16225 69437e154f249d7775268f8f15a55858 570 Pfam PF07730 Histidine kinase 379 439 1.8E-9 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CU254_RS16225 69437e154f249d7775268f8f15a55858 570 SUPERFAMILY SSF55781 202 389 2.4E-16 T 28-03-2018 IPR029016 GAF domain-like CU254_RS16225 69437e154f249d7775268f8f15a55858 570 Pfam PF13185 GAF domain 53 191 1.4E-19 T 28-03-2018 IPR003018 GAF domain GO:0005515 CU254_RS16225 69437e154f249d7775268f8f15a55858 570 Gene3D G3DSA:3.30.565.10 446 570 3.5E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS16225 69437e154f249d7775268f8f15a55858 570 SUPERFAMILY SSF55781 35 218 1.07E-37 T 28-03-2018 IPR029016 GAF domain-like CU254_RS16225 69437e154f249d7775268f8f15a55858 570 SMART SM00065 221 371 0.018 T 28-03-2018 IPR003018 GAF domain GO:0005515 CU254_RS16225 69437e154f249d7775268f8f15a55858 570 SMART SM00065 53 200 1.1E-18 T 28-03-2018 IPR003018 GAF domain GO:0005515 CU254_RS16225 69437e154f249d7775268f8f15a55858 570 Gene3D G3DSA:3.30.450.40 48 198 1.4E-32 T 28-03-2018 IPR029016 GAF domain-like CU254_RS16225 69437e154f249d7775268f8f15a55858 570 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 486 535 3.8E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS16225 69437e154f249d7775268f8f15a55858 570 SUPERFAMILY SSF55874 469 569 3.14E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS16225 69437e154f249d7775268f8f15a55858 570 Gene3D G3DSA:3.30.450.40 199 374 1.6E-20 T 28-03-2018 IPR029016 GAF domain-like CU254_RS16225 69437e154f249d7775268f8f15a55858 570 SMART SM00387 481 569 3.1E-4 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS09125 547c721d8a781753da3ed157fe7ee77a 317 Gene3D G3DSA:1.10.10.60 265 317 6.7E-9 T 28-03-2018 CU254_RS09125 547c721d8a781753da3ed157fe7ee77a 317 Gene3D G3DSA:1.10.10.60 231 264 1.1E-13 T 28-03-2018 CU254_RS09125 547c721d8a781753da3ed157fe7ee77a 317 SMART SM00342 229 312 1.0E-26 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS09125 547c721d8a781753da3ed157fe7ee77a 317 Pfam PF01965 DJ-1/PfpI family 88 174 6.4E-13 T 28-03-2018 IPR002818 DJ-1/PfpI CU254_RS09125 547c721d8a781753da3ed157fe7ee77a 317 SUPERFAMILY SSF46689 266 315 1.03E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS09125 547c721d8a781753da3ed157fe7ee77a 317 SUPERFAMILY SSF46689 215 263 1.03E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS09125 547c721d8a781753da3ed157fe7ee77a 317 Gene3D G3DSA:3.40.50.880 1 230 4.3E-57 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS09125 547c721d8a781753da3ed157fe7ee77a 317 SUPERFAMILY SSF52317 1 195 3.44E-42 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS09125 547c721d8a781753da3ed157fe7ee77a 317 Pfam PF12833 Helix-turn-helix domain 235 313 9.5E-20 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS25390 354001265e4730246a6e8fc272e31d4d 324 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 268 282 4.9E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS25390 354001265e4730246a6e8fc272e31d4d 324 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 282 298 4.9E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS25390 354001265e4730246a6e8fc272e31d4d 324 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 298 310 4.9E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS25390 354001265e4730246a6e8fc272e31d4d 324 Gene3D G3DSA:1.10.10.10 266 323 4.7E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS25390 354001265e4730246a6e8fc272e31d4d 324 Gene3D G3DSA:3.30.450.40 7 143 1.4E-7 T 28-03-2018 IPR029016 GAF domain-like CU254_RS25390 354001265e4730246a6e8fc272e31d4d 324 Pfam PF00196 Bacterial regulatory proteins, luxR family 267 319 1.0E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS25390 354001265e4730246a6e8fc272e31d4d 324 SUPERFAMILY SSF55781 72 142 1.07E-5 T 28-03-2018 IPR029016 GAF domain-like CU254_RS25390 354001265e4730246a6e8fc272e31d4d 324 ProSitePatterns PS00622 LuxR-type HTH domain signature. 282 309 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS25390 354001265e4730246a6e8fc272e31d4d 324 SMART SM00421 265 322 4.8E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS25390 354001265e4730246a6e8fc272e31d4d 324 SUPERFAMILY SSF46894 262 321 2.69E-16 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS11755 7477f5efa9a91f332d68404714408b6e 323 Pfam PF00107 Zinc-binding dehydrogenase 150 252 2.7E-27 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CU254_RS11755 7477f5efa9a91f332d68404714408b6e 323 SUPERFAMILY SSF50129 9 140 5.17E-39 T 28-03-2018 IPR011032 GroES-like CU254_RS11755 7477f5efa9a91f332d68404714408b6e 323 Gene3D G3DSA:3.90.180.10 2 133 1.4E-38 T 28-03-2018 CU254_RS11755 7477f5efa9a91f332d68404714408b6e 323 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 90 8.2E-11 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CU254_RS11755 7477f5efa9a91f332d68404714408b6e 323 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 139 160 - T 28-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 CU254_RS11755 7477f5efa9a91f332d68404714408b6e 323 SUPERFAMILY SSF51735 110 272 5.44E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS11755 7477f5efa9a91f332d68404714408b6e 323 SMART SM00829 11 321 5.4E-28 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CU254_RS11755 7477f5efa9a91f332d68404714408b6e 323 Gene3D G3DSA:3.40.50.720 134 291 4.7E-30 T 28-03-2018 CU254_RS24240 645ceaddd93dff4f7b7e8b2ceb4beb28 155 SUPERFAMILY SSF46785 26 147 6.51E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS24240 645ceaddd93dff4f7b7e8b2ceb4beb28 155 Pfam PF01047 MarR family 40 97 6.1E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS24240 645ceaddd93dff4f7b7e8b2ceb4beb28 155 PRINTS PR00598 Bacterial regulatory protein MarR family signature 123 143 7.1E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS24240 645ceaddd93dff4f7b7e8b2ceb4beb28 155 PRINTS PR00598 Bacterial regulatory protein MarR family signature 93 109 7.1E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS24240 645ceaddd93dff4f7b7e8b2ceb4beb28 155 PRINTS PR00598 Bacterial regulatory protein MarR family signature 74 89 7.1E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS24240 645ceaddd93dff4f7b7e8b2ceb4beb28 155 SMART SM00347 32 133 3.0E-23 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS24240 645ceaddd93dff4f7b7e8b2ceb4beb28 155 Gene3D G3DSA:1.10.10.10 2 155 9.8E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS25095 c6996f1bcb25e18b924ee837843620ea 450 SUPERFAMILY SSF158472 174 222 7.32E-6 T 28-03-2018 CU254_RS25095 c6996f1bcb25e18b924ee837843620ea 450 Pfam PF00512 His Kinase A (phospho-acceptor) domain 228 292 2.1E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS25095 c6996f1bcb25e18b924ee837843620ea 450 SUPERFAMILY SSF47384 212 294 9.02E-20 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS25095 c6996f1bcb25e18b924ee837843620ea 450 SMART SM00304 174 226 3.4E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS25095 c6996f1bcb25e18b924ee837843620ea 450 SMART SM00387 339 450 1.3E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS25095 c6996f1bcb25e18b924ee837843620ea 450 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 340 449 1.4E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS25095 c6996f1bcb25e18b924ee837843620ea 450 Gene3D G3DSA:3.30.565.10 288 450 3.5E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS25095 c6996f1bcb25e18b924ee837843620ea 450 SMART SM00388 227 293 1.0E-20 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS25095 c6996f1bcb25e18b924ee837843620ea 450 PRINTS PR00344 Bacterial sensor protein C-terminal signature 411 429 2.3E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS25095 c6996f1bcb25e18b924ee837843620ea 450 PRINTS PR00344 Bacterial sensor protein C-terminal signature 376 390 2.3E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS25095 c6996f1bcb25e18b924ee837843620ea 450 PRINTS PR00344 Bacterial sensor protein C-terminal signature 435 448 2.3E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS25095 c6996f1bcb25e18b924ee837843620ea 450 Pfam PF00672 HAMP domain 174 222 3.8E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS25095 c6996f1bcb25e18b924ee837843620ea 450 Gene3D G3DSA:1.10.287.130 217 287 1.8E-19 T 28-03-2018 CU254_RS25095 c6996f1bcb25e18b924ee837843620ea 450 SUPERFAMILY SSF55874 282 449 2.36E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS29665 865548e5ecc4f2868c0cf7c09c78ebd4 262 Pfam PF10703 MoaF N-terminal domain 10 111 9.4E-23 T 28-03-2018 IPR024724 Molybdenum cofactor biosynthesis protein F, N-terminal CU254_RS29665 865548e5ecc4f2868c0cf7c09c78ebd4 262 Pfam PF17409 MoaF C-terminal domain 137 251 3.0E-44 T 28-03-2018 IPR035348 MoaF, C-terminal domain CU254_RS29665 865548e5ecc4f2868c0cf7c09c78ebd4 262 Gene3D G3DSA:2.40.128.20 140 241 1.7E-22 T 28-03-2018 IPR012674 Calycin CU254_RS29665 865548e5ecc4f2868c0cf7c09c78ebd4 262 Gene3D G3DSA:2.40.128.20 31 130 7.9E-7 T 28-03-2018 IPR012674 Calycin CU254_RS16095 b4f0ac59c55c7a3f1f637859c160cf29 1034 Gene3D G3DSA:3.30.559.10 2 200 1.9E-41 T 28-03-2018 CU254_RS16095 b4f0ac59c55c7a3f1f637859c160cf29 1034 SUPERFAMILY SSF52777 9 179 4.67E-49 T 28-03-2018 CU254_RS16095 b4f0ac59c55c7a3f1f637859c160cf29 1034 SUPERFAMILY SSF52777 185 429 2.45E-56 T 28-03-2018 CU254_RS16095 b4f0ac59c55c7a3f1f637859c160cf29 1034 Gene3D G3DSA:3.40.50.980 455 605 2.5E-46 T 28-03-2018 CU254_RS16095 b4f0ac59c55c7a3f1f637859c160cf29 1034 SUPERFAMILY SSF56801 421 979 4.84E-149 T 28-03-2018 CU254_RS16095 b4f0ac59c55c7a3f1f637859c160cf29 1034 ProSitePatterns PS00012 Phosphopantetheine attachment site. 990 1005 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CU254_RS16095 b4f0ac59c55c7a3f1f637859c160cf29 1034 Gene3D G3DSA:3.40.50.980 606 766 3.4E-36 T 28-03-2018 CU254_RS16095 b4f0ac59c55c7a3f1f637859c160cf29 1034 ProSitePatterns PS00455 Putative AMP-binding domain signature. 600 611 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS16095 b4f0ac59c55c7a3f1f637859c160cf29 1034 Pfam PF00501 AMP-binding enzyme 462 858 2.1E-91 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS16095 b4f0ac59c55c7a3f1f637859c160cf29 1034 Pfam PF00550 Phosphopantetheine attachment site 968 1028 6.2E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS16095 b4f0ac59c55c7a3f1f637859c160cf29 1034 Gene3D G3DSA:2.30.38.10 768 848 2.3E-24 T 28-03-2018 CU254_RS16095 b4f0ac59c55c7a3f1f637859c160cf29 1034 Gene3D G3DSA:1.10.1200.10 972 1034 4.4E-24 T 28-03-2018 CU254_RS16095 b4f0ac59c55c7a3f1f637859c160cf29 1034 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 483 882 1.6E-128 T 28-03-2018 IPR010071 Amino acid adenylation domain CU254_RS16095 b4f0ac59c55c7a3f1f637859c160cf29 1034 SUPERFAMILY SSF47336 959 1031 8.24E-20 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS16095 b4f0ac59c55c7a3f1f637859c160cf29 1034 Pfam PF13193 AMP-binding enzyme C-terminal domain 866 938 3.0E-12 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS16095 b4f0ac59c55c7a3f1f637859c160cf29 1034 Pfam PF00668 Condensation domain 5 441 3.6E-92 T 28-03-2018 IPR001242 Condensation domain CU254_RS16095 b4f0ac59c55c7a3f1f637859c160cf29 1034 Gene3D G3DSA:3.30.300.30 853 971 1.0E-37 T 28-03-2018 CU254_RS40525 c3fc25420eef2341d55da2fc9771def5 267 SUPERFAMILY SSF52540 5 241 1.13E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS40525 c3fc25420eef2341d55da2fc9771def5 267 Gene3D G3DSA:3.40.50.300 1 262 1.1E-61 T 28-03-2018 CU254_RS40525 c3fc25420eef2341d55da2fc9771def5 267 Pfam PF00005 ABC transporter 26 164 5.3E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS40525 c3fc25420eef2341d55da2fc9771def5 267 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS40525 c3fc25420eef2341d55da2fc9771def5 267 SMART SM00382 34 214 9.2E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS08195 502fb21d05e17c9416881478bb5b2592 511 Pfam PF13487 HD domain 338 390 1.6E-16 T 28-03-2018 CU254_RS08195 502fb21d05e17c9416881478bb5b2592 511 SMART SM00421 447 504 2.2E-23 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS08195 502fb21d05e17c9416881478bb5b2592 511 Pfam PF00196 Bacterial regulatory proteins, luxR family 450 504 7.4E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS08195 502fb21d05e17c9416881478bb5b2592 511 Gene3D G3DSA:1.10.3210.10 250 442 1.5E-31 T 28-03-2018 CU254_RS08195 502fb21d05e17c9416881478bb5b2592 511 Gene3D G3DSA:1.10.3210.10 4 238 4.0E-19 T 28-03-2018 CU254_RS08195 502fb21d05e17c9416881478bb5b2592 511 ProSitePatterns PS00622 LuxR-type HTH domain signature. 464 491 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS08195 502fb21d05e17c9416881478bb5b2592 511 SMART SM00471 273 408 9.3E-4 T 28-03-2018 IPR003607 HD/PDEase domain CU254_RS08195 502fb21d05e17c9416881478bb5b2592 511 SUPERFAMILY SSF46894 440 510 9.18E-21 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS08195 502fb21d05e17c9416881478bb5b2592 511 SUPERFAMILY SSF109604 266 436 2.88E-22 T 28-03-2018 CU254_RS08195 502fb21d05e17c9416881478bb5b2592 511 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 464 480 7.0E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS08195 502fb21d05e17c9416881478bb5b2592 511 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 480 492 7.0E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS08195 502fb21d05e17c9416881478bb5b2592 511 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 450 464 7.0E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS08195 502fb21d05e17c9416881478bb5b2592 511 Gene3D G3DSA:1.10.10.10 443 511 8.0E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS08195 502fb21d05e17c9416881478bb5b2592 511 SUPERFAMILY SSF109604 124 226 3.66E-5 T 28-03-2018 CU254_RS20490 0eda2a582e9c17e51dba29bdf771de11 545 SUPERFAMILY SSF52540 349 543 2.32E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS20490 0eda2a582e9c17e51dba29bdf771de11 545 SMART SM00382 374 541 1.5E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS20490 0eda2a582e9c17e51dba29bdf771de11 545 SMART SM00382 29 232 6.6E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS20490 0eda2a582e9c17e51dba29bdf771de11 545 Gene3D G3DSA:3.40.50.300 1 324 1.7E-48 T 28-03-2018 CU254_RS20490 0eda2a582e9c17e51dba29bdf771de11 545 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS20490 0eda2a582e9c17e51dba29bdf771de11 545 Gene3D G3DSA:3.40.50.300 325 545 2.1E-37 T 28-03-2018 CU254_RS20490 0eda2a582e9c17e51dba29bdf771de11 545 Pfam PF00005 ABC transporter 367 495 4.2E-15 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS20490 0eda2a582e9c17e51dba29bdf771de11 545 Pfam PF00005 ABC transporter 22 187 1.3E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS20490 0eda2a582e9c17e51dba29bdf771de11 545 SUPERFAMILY SSF52540 128 253 2.89E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS20490 0eda2a582e9c17e51dba29bdf771de11 545 SUPERFAMILY SSF52540 5 95 2.89E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS09885 b80e8fadc7ea9618e5039ace7d1264e6 238 Pfam PF10518 TAT (twin-arginine translocation) pathway signal sequence 2 23 2.8E-5 T 28-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal CU254_RS09885 b80e8fadc7ea9618e5039ace7d1264e6 238 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 2 25 7.5E-4 T 28-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal CU254_RS09885 b80e8fadc7ea9618e5039ace7d1264e6 238 SUPERFAMILY SSF52317 37 229 1.91E-39 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS09885 b80e8fadc7ea9618e5039ace7d1264e6 238 Pfam PF01965 DJ-1/PfpI family 39 211 5.3E-23 T 28-03-2018 IPR002818 DJ-1/PfpI CU254_RS09885 b80e8fadc7ea9618e5039ace7d1264e6 238 Gene3D G3DSA:3.40.50.880 33 238 4.3E-48 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS22705 6decdb4009ae0e0d7fc9e856aabc60b2 132 Gene3D G3DSA:3.90.79.10 2 128 4.2E-18 T 28-03-2018 CU254_RS22705 6decdb4009ae0e0d7fc9e856aabc60b2 132 Pfam PF00293 NUDIX domain 13 111 7.0E-12 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CU254_RS22705 6decdb4009ae0e0d7fc9e856aabc60b2 132 ProSitePatterns PS00893 Nudix box signature. 33 54 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CU254_RS22705 6decdb4009ae0e0d7fc9e856aabc60b2 132 SUPERFAMILY SSF55811 7 124 8.26E-19 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CU254_RS16290 deab0b52ea98819d47d4e0b88a064715 550 SUPERFAMILY SSF90123 6 313 1.44E-38 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CU254_RS16290 deab0b52ea98819d47d4e0b88a064715 550 Pfam PF00664 ABC transporter transmembrane region 22 279 2.4E-15 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CU254_RS16290 deab0b52ea98819d47d4e0b88a064715 550 Gene3D G3DSA:3.40.50.300 323 544 9.7E-49 T 28-03-2018 CU254_RS16290 deab0b52ea98819d47d4e0b88a064715 550 Gene3D G3DSA:1.20.1560.10 4 313 6.3E-36 T 28-03-2018 CU254_RS16290 deab0b52ea98819d47d4e0b88a064715 550 ProSitePatterns PS00211 ABC transporters family signature. 456 470 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS16290 deab0b52ea98819d47d4e0b88a064715 550 SUPERFAMILY SSF52540 333 542 5.92E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS16290 deab0b52ea98819d47d4e0b88a064715 550 Pfam PF00005 ABC transporter 338 484 6.8E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS16290 deab0b52ea98819d47d4e0b88a064715 550 SMART SM00382 347 526 2.2E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS26290 e34e91879dae6b4c0b2ee2d37265040d 255 Gene3D G3DSA:1.10.150.290 178 233 5.5E-24 T 28-03-2018 IPR023149 Trans-aconitate 2-methyltransferase, C-terminal GO:0030798 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CU254_RS26290 e34e91879dae6b4c0b2ee2d37265040d 255 Gene3D G3DSA:3.40.50.150 1 177 5.4E-24 T 28-03-2018 CU254_RS26290 e34e91879dae6b4c0b2ee2d37265040d 255 Pfam PF13649 Methyltransferase domain 33 113 5.8E-11 T 28-03-2018 CU254_RS26290 e34e91879dae6b4c0b2ee2d37265040d 255 SUPERFAMILY SSF53335 21 245 3.75E-27 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS05860 b9e3852dbb27682c0b88577c3d18881c 537 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 32 116 2.6E-6 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS05860 b9e3852dbb27682c0b88577c3d18881c 537 SUPERFAMILY SSF56645 31 213 9.87E-31 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS05860 b9e3852dbb27682c0b88577c3d18881c 537 Gene3D G3DSA:2.40.110.10 120 216 3.8E-14 T 28-03-2018 CU254_RS05860 b9e3852dbb27682c0b88577c3d18881c 537 Gene3D G3DSA:1.10.540.10 13 119 1.5E-9 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS05860 b9e3852dbb27682c0b88577c3d18881c 537 SUPERFAMILY SSF47203 225 370 5.8E-16 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS05860 b9e3852dbb27682c0b88577c3d18881c 537 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 225 373 1.2E-12 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS05860 b9e3852dbb27682c0b88577c3d18881c 537 Gene3D G3DSA:1.20.140.10 217 385 2.1E-19 T 28-03-2018 CU254_RS05860 b9e3852dbb27682c0b88577c3d18881c 537 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 120 211 1.7E-13 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CU254_RS13615 7733a837d920b75858503788e40e3ce3 356 Gene3D G3DSA:1.10.260.40 8 96 1.2E-11 T 28-03-2018 CU254_RS13615 7733a837d920b75858503788e40e3ce3 356 Pfam PF13560 Helix-turn-helix domain 8 56 8.2E-8 T 28-03-2018 CU254_RS13615 7733a837d920b75858503788e40e3ce3 356 SUPERFAMILY SSF47413 6 54 1.84E-9 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS13615 7733a837d920b75858503788e40e3ce3 356 SMART SM00530 8 62 4.0E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS21225 dbd01d57877c39be288a61ed966ef801 300 Gene3D G3DSA:3.40.50.1820 1 295 8.8E-31 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS21225 dbd01d57877c39be288a61ed966ef801 300 SUPERFAMILY SSF53474 4 245 1.04E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS21225 dbd01d57877c39be288a61ed966ef801 300 Pfam PF12740 Chlorophyllase enzyme 28 142 3.3E-9 T 28-03-2018 IPR017395 Chlorophyllase GO:0015996|GO:0047746 KEGG: 00860+3.1.1.14|MetaCyc: PWY-5098|MetaCyc: PWY-6927|MetaCyc: PWY-7164 CU254_RS13365 88e99e7e81af7ba604b7ffd9613a62aa 682 Gene3D G3DSA:1.10.3810.10 35 246 4.6E-69 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CU254_RS13365 88e99e7e81af7ba604b7ffd9613a62aa 682 Pfam PF00905 Penicillin binding protein transpeptidase domain 338 600 2.0E-20 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CU254_RS13365 88e99e7e81af7ba604b7ffd9613a62aa 682 Pfam PF00912 Transglycosylase 44 228 1.1E-57 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CU254_RS13365 88e99e7e81af7ba604b7ffd9613a62aa 682 Gene3D G3DSA:3.40.710.10 260 679 6.7E-70 T 28-03-2018 CU254_RS13365 88e99e7e81af7ba604b7ffd9613a62aa 682 SUPERFAMILY SSF56601 269 471 3.0E-66 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CU254_RS13365 88e99e7e81af7ba604b7ffd9613a62aa 682 SUPERFAMILY SSF56601 503 675 3.0E-66 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CU254_RS13365 88e99e7e81af7ba604b7ffd9613a62aa 682 SUPERFAMILY SSF56601 210 232 3.0E-66 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CU254_RS13365 88e99e7e81af7ba604b7ffd9613a62aa 682 SUPERFAMILY SSF53955 30 250 8.44E-65 T 28-03-2018 IPR023346 Lysozyme-like domain CU254_RS20705 b1c67caeb26c38bc569175e7afb3e7fe 672 Gene3D G3DSA:3.40.50.261 132 295 3.3E-30 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CU254_RS20705 b1c67caeb26c38bc569175e7afb3e7fe 672 Pfam PF13549 ATP-grasp domain 458 661 8.8E-21 T 28-03-2018 CU254_RS20705 b1c67caeb26c38bc569175e7afb3e7fe 672 SUPERFAMILY SSF52210 465 487 5.23E-20 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CU254_RS20705 b1c67caeb26c38bc569175e7afb3e7fe 672 SUPERFAMILY SSF52210 298 417 5.23E-20 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CU254_RS20705 b1c67caeb26c38bc569175e7afb3e7fe 672 SUPERFAMILY SSF56059 466 663 1.87E-18 T 28-03-2018 CU254_RS20705 b1c67caeb26c38bc569175e7afb3e7fe 672 SUPERFAMILY SSF52210 144 290 2.88E-31 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CU254_RS20705 b1c67caeb26c38bc569175e7afb3e7fe 672 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 153 288 2.7E-34 T 28-03-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain CU254_RS20705 b1c67caeb26c38bc569175e7afb3e7fe 672 Gene3D G3DSA:3.40.50.720 1 131 6.4E-28 T 28-03-2018 CU254_RS20705 b1c67caeb26c38bc569175e7afb3e7fe 672 Pfam PF13380 CoA binding domain 10 132 6.3E-12 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CU254_RS20705 b1c67caeb26c38bc569175e7afb3e7fe 672 Gene3D G3DSA:3.40.50.261 296 491 4.8E-24 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CU254_RS20705 b1c67caeb26c38bc569175e7afb3e7fe 672 SMART SM00881 6 102 2.2E-17 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CU254_RS20705 b1c67caeb26c38bc569175e7afb3e7fe 672 SUPERFAMILY SSF51735 4 134 1.9E-23 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS20705 b1c67caeb26c38bc569175e7afb3e7fe 672 Gene3D G3DSA:3.30.470.20 542 671 8.9E-14 T 28-03-2018 CU254_RS20705 b1c67caeb26c38bc569175e7afb3e7fe 672 Gene3D G3DSA:3.30.1490.20 492 541 3.0E-4 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CU254_RS02060 15f7062323f079d257d64ceee266decd 184 SUPERFAMILY SSF52540 3 180 5.71E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS02060 15f7062323f079d257d64ceee266decd 184 Gene3D G3DSA:3.40.50.300 3 129 1.2E-38 T 28-03-2018 CU254_RS02060 15f7062323f079d257d64ceee266decd 184 Gene3D G3DSA:3.40.50.300 130 184 6.5E-7 T 28-03-2018 CU254_RS02060 15f7062323f079d257d64ceee266decd 184 PRINTS PR00094 Adenylate kinase signature 33 47 1.4E-29 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CU254_RS02060 15f7062323f079d257d64ceee266decd 184 PRINTS PR00094 Adenylate kinase signature 82 98 1.4E-29 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CU254_RS02060 15f7062323f079d257d64ceee266decd 184 PRINTS PR00094 Adenylate kinase signature 147 161 1.4E-29 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CU254_RS02060 15f7062323f079d257d64ceee266decd 184 PRINTS PR00094 Adenylate kinase signature 5 18 1.4E-29 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CU254_RS02060 15f7062323f079d257d64ceee266decd 184 PRINTS PR00094 Adenylate kinase signature 130 145 1.4E-29 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CU254_RS02060 15f7062323f079d257d64ceee266decd 184 ProSitePatterns PS00113 Adenylate kinase signature. 82 93 - T 28-03-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CU254_RS02060 15f7062323f079d257d64ceee266decd 184 TIGRFAM TIGR01351 adk: adenylate kinase 3 128 7.9E-51 T 28-03-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 CU254_RS02060 15f7062323f079d257d64ceee266decd 184 Hamap MF_00235 Adenylate kinase [adk]. 2 181 41.674 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CU254_RS02060 15f7062323f079d257d64ceee266decd 184 Pfam PF00406 Adenylate kinase 6 158 1.9E-52 T 28-03-2018 CU254_RS38755 2c9d6e63ec91e8f8bb67a0b16c0b82af 200 SUPERFAMILY SSF46689 8 87 1.55E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS38755 2c9d6e63ec91e8f8bb67a0b16c0b82af 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 1.6E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS38755 2c9d6e63ec91e8f8bb67a0b16c0b82af 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 1.6E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS38755 2c9d6e63ec91e8f8bb67a0b16c0b82af 200 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 103 196 3.3E-10 T 28-03-2018 CU254_RS38755 2c9d6e63ec91e8f8bb67a0b16c0b82af 200 Gene3D G3DSA:1.10.357.10 69 200 4.3E-19 T 28-03-2018 CU254_RS38755 2c9d6e63ec91e8f8bb67a0b16c0b82af 200 ProSitePatterns PS01081 TetR-type HTH domain signature. 29 59 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CU254_RS38755 2c9d6e63ec91e8f8bb67a0b16c0b82af 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 60 1.1E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS38755 2c9d6e63ec91e8f8bb67a0b16c0b82af 200 SUPERFAMILY SSF48498 83 196 8.12E-14 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS38755 2c9d6e63ec91e8f8bb67a0b16c0b82af 200 Gene3D G3DSA:1.10.10.60 2 68 1.8E-18 T 28-03-2018 CU254_RS09325 a35ccdec12cd3a308390fe28bd5aa677 269 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 2 257 33.698 T 28-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 CU254_RS09325 a35ccdec12cd3a308390fe28bd5aa677 269 Gene3D G3DSA:3.20.20.70 10 260 1.8E-70 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS09325 a35ccdec12cd3a308390fe28bd5aa677 269 Pfam PF00218 Indole-3-glycerol phosphate synthase 4 253 7.9E-82 T 28-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 CU254_RS09325 a35ccdec12cd3a308390fe28bd5aa677 269 SUPERFAMILY SSF51366 12 257 1.41E-78 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CU254_RS09325 a35ccdec12cd3a308390fe28bd5aa677 269 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 51 68 - T 28-03-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 CU254_RS10945 1a5ff38fa39a12719a5f0347451546be 638 Pfam PF02780 Transketolase, C-terminal domain 499 612 5.1E-26 T 28-03-2018 IPR033248 Transketolase, C-terminal domain CU254_RS10945 1a5ff38fa39a12719a5f0347451546be 638 ProSitePatterns PS00801 Transketolase signature 1. 29 48 - T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CU254_RS10945 1a5ff38fa39a12719a5f0347451546be 638 Pfam PF02779 Transketolase, pyrimidine binding domain 315 478 1.2E-39 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CU254_RS10945 1a5ff38fa39a12719a5f0347451546be 638 SUPERFAMILY SSF52518 295 478 5.66E-56 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS10945 1a5ff38fa39a12719a5f0347451546be 638 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 3 621 40.867 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CU254_RS10945 1a5ff38fa39a12719a5f0347451546be 638 Gene3D G3DSA:3.40.50.970 297 484 7.9E-50 T 28-03-2018 CU254_RS10945 1a5ff38fa39a12719a5f0347451546be 638 SUPERFAMILY SSF52922 489 619 1.02E-25 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CU254_RS10945 1a5ff38fa39a12719a5f0347451546be 638 Gene3D G3DSA:3.40.50.970 1 296 4.4E-74 T 28-03-2018 CU254_RS10945 1a5ff38fa39a12719a5f0347451546be 638 SUPERFAMILY SSF52518 3 345 5.08E-65 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS10945 1a5ff38fa39a12719a5f0347451546be 638 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 6 619 1.4E-182 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CU254_RS10945 1a5ff38fa39a12719a5f0347451546be 638 SMART SM00861 316 480 2.4E-59 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CU254_RS10945 1a5ff38fa39a12719a5f0347451546be 638 Gene3D G3DSA:3.40.50.920 489 622 3.1E-31 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CU254_RS10945 1a5ff38fa39a12719a5f0347451546be 638 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 4 281 2.8E-104 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CU254_RS10945 1a5ff38fa39a12719a5f0347451546be 638 ProSitePatterns PS00802 Transketolase signature 2. 422 438 - T 28-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CU254_RS34595 28710022ed4dde53189e08c47962e18f 203 Pfam PF10067 Predicted membrane protein (DUF2306) 36 192 1.0E-30 T 28-03-2018 IPR018750 Protein of unknown function DUF2306, membrane CU254_RS22875 0ecfe62b8cee3e422088db77414a259b 912 Gene3D G3DSA:1.10.150.20 204 282 3.4E-26 T 28-03-2018 CU254_RS22875 0ecfe62b8cee3e422088db77414a259b 912 SUPERFAMILY SSF88723 19 190 1.21E-53 T 28-03-2018 IPR029060 PIN domain-like CU254_RS22875 0ecfe62b8cee3e422088db77414a259b 912 SUPERFAMILY SSF56672 508 910 2.78E-136 T 28-03-2018 CU254_RS22875 0ecfe62b8cee3e422088db77414a259b 912 TIGRFAM TIGR00593 pola: DNA polymerase I 24 910 6.1E-301 T 28-03-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CU254_RS22875 0ecfe62b8cee3e422088db77414a259b 912 Pfam PF01612 3'-5' exonuclease 355 453 7.5E-7 T 28-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 CU254_RS22875 0ecfe62b8cee3e422088db77414a259b 912 SMART SM00482 668 875 3.5E-109 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CU254_RS22875 0ecfe62b8cee3e422088db77414a259b 912 Gene3D G3DSA:3.30.70.370 639 729 1.8E-15 T 28-03-2018 CU254_RS22875 0ecfe62b8cee3e422088db77414a259b 912 Gene3D G3DSA:3.30.70.370 737 912 3.6E-45 T 28-03-2018 CU254_RS22875 0ecfe62b8cee3e422088db77414a259b 912 SMART SM00279 193 228 4.7E-15 T 28-03-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 CU254_RS22875 0ecfe62b8cee3e422088db77414a259b 912 Gene3D G3DSA:1.20.1060.10 526 638 8.9E-27 T 28-03-2018 CU254_RS22875 0ecfe62b8cee3e422088db77414a259b 912 Pfam PF00476 DNA polymerase family A 533 909 7.2E-141 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CU254_RS22875 0ecfe62b8cee3e422088db77414a259b 912 SUPERFAMILY SSF47807 191 304 2.99E-31 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CU254_RS22875 0ecfe62b8cee3e422088db77414a259b 912 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 192 285 8.9E-28 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CU254_RS22875 0ecfe62b8cee3e422088db77414a259b 912 SMART SM00474 322 501 3.8E-10 T 28-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 CU254_RS22875 0ecfe62b8cee3e422088db77414a259b 912 Gene3D G3DSA:3.40.50.1010 22 203 4.1E-67 T 28-03-2018 IPR029060 PIN domain-like CU254_RS22875 0ecfe62b8cee3e422088db77414a259b 912 PRINTS PR00868 DNA-polymerase family A (pol I) signature 828 844 3.6E-73 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CU254_RS22875 0ecfe62b8cee3e422088db77414a259b 912 PRINTS PR00868 DNA-polymerase family A (pol I) signature 637 659 3.6E-73 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CU254_RS22875 0ecfe62b8cee3e422088db77414a259b 912 PRINTS PR00868 DNA-polymerase family A (pol I) signature 858 871 3.6E-73 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CU254_RS22875 0ecfe62b8cee3e422088db77414a259b 912 PRINTS PR00868 DNA-polymerase family A (pol I) signature 660 675 3.6E-73 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CU254_RS22875 0ecfe62b8cee3e422088db77414a259b 912 PRINTS PR00868 DNA-polymerase family A (pol I) signature 796 807 3.6E-73 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CU254_RS22875 0ecfe62b8cee3e422088db77414a259b 912 PRINTS PR00868 DNA-polymerase family A (pol I) signature 683 706 3.6E-73 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CU254_RS22875 0ecfe62b8cee3e422088db77414a259b 912 PRINTS PR00868 DNA-polymerase family A (pol I) signature 774 785 3.6E-73 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CU254_RS22875 0ecfe62b8cee3e422088db77414a259b 912 PRINTS PR00868 DNA-polymerase family A (pol I) signature 713 726 3.6E-73 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CU254_RS22875 0ecfe62b8cee3e422088db77414a259b 912 PRINTS PR00868 DNA-polymerase family A (pol I) signature 737 762 3.6E-73 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CU254_RS22875 0ecfe62b8cee3e422088db77414a259b 912 SUPERFAMILY SSF53098 328 502 7.08E-31 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS22875 0ecfe62b8cee3e422088db77414a259b 912 Gene3D G3DSA:3.30.420.10 334 525 1.1E-26 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS22875 0ecfe62b8cee3e422088db77414a259b 912 SMART SM00475 20 281 5.6E-136 T 28-03-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 CU254_RS22875 0ecfe62b8cee3e422088db77414a259b 912 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 23 190 1.7E-55 T 28-03-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 CU254_RS22875 0ecfe62b8cee3e422088db77414a259b 912 ProSitePatterns PS00447 DNA polymerase family A signature. 737 756 - T 28-03-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CU254_RS01845 5b10473df901d9c8d251f5bc6eb54427 192 Gene3D G3DSA:3.30.1310.10 2 110 2.7E-18 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CU254_RS01845 5b10473df901d9c8d251f5bc6eb54427 192 Pfam PF02575 YbaB/EbfC DNA-binding family 28 105 1.3E-8 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CU254_RS01845 5b10473df901d9c8d251f5bc6eb54427 192 SUPERFAMILY SSF82607 28 97 2.75E-7 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CU254_RS06670 4f8c14135bea1dc81a99166e3fb027cc 263 Gene3D G3DSA:3.40.50.1820 3 261 9.5E-47 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS06670 4f8c14135bea1dc81a99166e3fb027cc 263 Pfam PF12697 Alpha/beta hydrolase family 23 252 8.5E-18 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS06670 4f8c14135bea1dc81a99166e3fb027cc 263 SUPERFAMILY SSF53474 1 260 2.01E-58 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS06670 4f8c14135bea1dc81a99166e3fb027cc 263 PRINTS PR00111 Alpha/beta hydrolase fold signature 92 105 9.4E-9 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS06670 4f8c14135bea1dc81a99166e3fb027cc 263 PRINTS PR00111 Alpha/beta hydrolase fold signature 46 61 9.4E-9 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS06670 4f8c14135bea1dc81a99166e3fb027cc 263 PRINTS PR00111 Alpha/beta hydrolase fold signature 106 119 9.4E-9 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS06670 4f8c14135bea1dc81a99166e3fb027cc 263 PRINTS PR00111 Alpha/beta hydrolase fold signature 204 218 9.4E-9 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS29870 f01f285468cd764e46b34658aec3ad8b 368 Gene3D G3DSA:3.10.560.10 192 315 6.7E-5 T 28-03-2018 CU254_RS29870 f01f285468cd764e46b34658aec3ad8b 368 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 275 355 1.0E-12 T 28-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS29870 f01f285468cd764e46b34658aec3ad8b 368 SUPERFAMILY SSF142019 19 193 1.1E-42 T 28-03-2018 CU254_RS29870 f01f285468cd764e46b34658aec3ad8b 368 SUPERFAMILY SSF142984 197 248 7.32E-8 T 28-03-2018 CU254_RS29870 f01f285468cd764e46b34658aec3ad8b 368 Pfam PF10531 SLBB domain 197 227 2.3E-8 T 28-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS29870 f01f285468cd764e46b34658aec3ad8b 368 SMART SM00928 273 318 0.003 T 28-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS29870 f01f285468cd764e46b34658aec3ad8b 368 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 32 179 6.2E-33 T 28-03-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS29870 f01f285468cd764e46b34658aec3ad8b 368 SUPERFAMILY SSF140490 270 363 1.57E-13 T 28-03-2018 CU254_RS40030 070e9fb94d1870ea87b3ed847937c848 211 SMART SM00346 6 93 3.0E-13 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS40030 070e9fb94d1870ea87b3ed847937c848 211 Gene3D G3DSA:1.10.10.10 2 72 1.6E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS40030 070e9fb94d1870ea87b3ed847937c848 211 Pfam PF09339 IclR helix-turn-helix domain 8 60 6.5E-10 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS40030 070e9fb94d1870ea87b3ed847937c848 211 SUPERFAMILY SSF55781 64 209 9.81E-18 T 28-03-2018 IPR029016 GAF domain-like CU254_RS40030 070e9fb94d1870ea87b3ed847937c848 211 SUPERFAMILY SSF46785 8 77 2.46E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS40030 070e9fb94d1870ea87b3ed847937c848 211 Gene3D G3DSA:3.30.450.40 147 211 1.0E-4 T 28-03-2018 IPR029016 GAF domain-like CU254_RS40030 070e9fb94d1870ea87b3ed847937c848 211 Gene3D G3DSA:3.30.450.40 73 146 3.2E-15 T 28-03-2018 IPR029016 GAF domain-like CU254_RS35445 e432511470b4d7b6f972714608d2bed1 762 ProSitePatterns PS00674 AAA-protein family signature. 637 655 - T 28-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 CU254_RS35445 e432511470b4d7b6f972714608d2bed1 762 SUPERFAMILY SSF50692 5 89 1.11E-11 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain CU254_RS35445 e432511470b4d7b6f972714608d2bed1 762 Gene3D G3DSA:2.40.40.20 2 86 6.2E-20 T 28-03-2018 CU254_RS35445 e432511470b4d7b6f972714608d2bed1 762 SUPERFAMILY SSF52540 497 755 1.12E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS35445 e432511470b4d7b6f972714608d2bed1 762 Gene3D G3DSA:3.10.330.10 87 193 1.3E-5 T 28-03-2018 IPR029067 CDC48 domain 2-like CU254_RS35445 e432511470b4d7b6f972714608d2bed1 762 SMART SM00382 276 407 8.3E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS35445 e432511470b4d7b6f972714608d2bed1 762 SMART SM00382 532 669 2.1E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS35445 e432511470b4d7b6f972714608d2bed1 762 Gene3D G3DSA:1.10.8.60 413 490 3.1E-16 T 28-03-2018 CU254_RS35445 e432511470b4d7b6f972714608d2bed1 762 Gene3D G3DSA:1.10.8.60 675 762 5.1E-21 T 28-03-2018 CU254_RS35445 e432511470b4d7b6f972714608d2bed1 762 Pfam PF02359 Cell division protein 48 (CDC48), N-terminal domain 8 91 4.5E-15 T 28-03-2018 IPR003338 CDC48, N-terminal subdomain CU254_RS35445 e432511470b4d7b6f972714608d2bed1 762 SMART SM01072 108 192 1.2E-4 T 28-03-2018 IPR004201 CDC48, domain 2 CU254_RS35445 e432511470b4d7b6f972714608d2bed1 762 SUPERFAMILY SSF52540 238 482 2.83E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS35445 e432511470b4d7b6f972714608d2bed1 762 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 280 404 8.9E-14 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CU254_RS35445 e432511470b4d7b6f972714608d2bed1 762 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 536 666 7.9E-40 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CU254_RS35445 e432511470b4d7b6f972714608d2bed1 762 Gene3D G3DSA:3.40.50.300 229 412 5.8E-23 T 28-03-2018 CU254_RS35445 e432511470b4d7b6f972714608d2bed1 762 Gene3D G3DSA:3.40.50.300 496 674 5.4E-53 T 28-03-2018 CU254_RS35445 e432511470b4d7b6f972714608d2bed1 762 SMART SM01073 7 91 1.1E-20 T 28-03-2018 IPR003338 CDC48, N-terminal subdomain CU254_RS26685 5c00740e9ec5ad7a0f293cf7b8f24679 616 TIGRFAM TIGR01393 lepA: elongation factor 4 17 608 1.5E-295 T 28-03-2018 IPR006297 Elongation factor 4 GO:0005525 CU254_RS26685 5c00740e9ec5ad7a0f293cf7b8f24679 616 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 56 71 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site CU254_RS26685 5c00740e9ec5ad7a0f293cf7b8f24679 616 SUPERFAMILY SSF50447 195 296 1.09E-17 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CU254_RS26685 5c00740e9ec5ad7a0f293cf7b8f24679 616 SUPERFAMILY SSF54980 412 507 2.49E-23 T 28-03-2018 IPR035647 EF-G domain III/V-like CU254_RS26685 5c00740e9ec5ad7a0f293cf7b8f24679 616 Gene3D G3DSA:2.40.30.10 201 300 1.1E-21 T 28-03-2018 CU254_RS26685 5c00740e9ec5ad7a0f293cf7b8f24679 616 Pfam PF06421 GTP-binding protein LepA C-terminus 502 606 1.4E-48 T 28-03-2018 IPR013842 GTP-binding protein LepA, C-terminal CU254_RS26685 5c00740e9ec5ad7a0f293cf7b8f24679 616 Hamap MF_00071 Elongation factor 4 [lepA]. 1 611 285.354 T 28-03-2018 IPR006297 Elongation factor 4 GO:0005525 CU254_RS26685 5c00740e9ec5ad7a0f293cf7b8f24679 616 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 20 188 4.2E-19 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CU254_RS26685 5c00740e9ec5ad7a0f293cf7b8f24679 616 SMART SM00838 414 499 2.9E-4 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CU254_RS26685 5c00740e9ec5ad7a0f293cf7b8f24679 616 Gene3D G3DSA:3.30.70.870 301 380 2.9E-28 T 28-03-2018 CU254_RS26685 5c00740e9ec5ad7a0f293cf7b8f24679 616 Gene3D G3DSA:3.40.50.300 16 198 9.2E-37 T 28-03-2018 CU254_RS26685 5c00740e9ec5ad7a0f293cf7b8f24679 616 PRINTS PR00315 GTP-binding elongation factor signature 103 114 3.0E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CU254_RS26685 5c00740e9ec5ad7a0f293cf7b8f24679 616 PRINTS PR00315 GTP-binding elongation factor signature 63 71 3.0E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CU254_RS26685 5c00740e9ec5ad7a0f293cf7b8f24679 616 PRINTS PR00315 GTP-binding elongation factor signature 87 97 3.0E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CU254_RS26685 5c00740e9ec5ad7a0f293cf7b8f24679 616 PRINTS PR00315 GTP-binding elongation factor signature 20 33 3.0E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CU254_RS26685 5c00740e9ec5ad7a0f293cf7b8f24679 616 PRINTS PR00315 GTP-binding elongation factor signature 139 148 3.0E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CU254_RS26685 5c00740e9ec5ad7a0f293cf7b8f24679 616 SUPERFAMILY SSF54980 304 383 1.22E-19 T 28-03-2018 IPR035647 EF-G domain III/V-like CU254_RS26685 5c00740e9ec5ad7a0f293cf7b8f24679 616 Pfam PF00009 Elongation factor Tu GTP binding domain 18 194 6.4E-52 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CU254_RS26685 5c00740e9ec5ad7a0f293cf7b8f24679 616 SUPERFAMILY SSF52540 12 219 1.25E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS26685 5c00740e9ec5ad7a0f293cf7b8f24679 616 Gene3D G3DSA:3.30.70.240 407 562 1.9E-27 T 28-03-2018 CU254_RS26685 5c00740e9ec5ad7a0f293cf7b8f24679 616 Pfam PF00679 Elongation factor G C-terminus 412 498 7.6E-21 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CU254_RS24380 73f1cd376b0575337aea6ba9b4a64e04 789 Pfam PF03632 Glycosyl hydrolase family 65 central catalytic domain 326 695 4.1E-134 T 28-03-2018 IPR005195 Glycoside hydrolase, family 65, central catalytic GO:0003824|GO:0005975 CU254_RS24380 73f1cd376b0575337aea6ba9b4a64e04 789 Pfam PF03633 Glycosyl hydrolase family 65, C-terminal domain 699 749 6.7E-16 T 28-03-2018 IPR005194 Glycoside hydrolase family 65, C-terminal CU254_RS24380 73f1cd376b0575337aea6ba9b4a64e04 789 Gene3D G3DSA:2.60.420.10 681 752 1.3E-24 T 28-03-2018 CU254_RS24380 73f1cd376b0575337aea6ba9b4a64e04 789 SUPERFAMILY SSF48208 278 747 1.81E-119 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CU254_RS24380 73f1cd376b0575337aea6ba9b4a64e04 789 Gene3D G3DSA:2.70.98.40 3 273 1.8E-78 T 28-03-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 CU254_RS24380 73f1cd376b0575337aea6ba9b4a64e04 789 PIRSF PIRSF036289 2 761 9.4E-215 T 28-03-2018 IPR017045 Maltose phosphorylase/glycosyl hydrolase/vacuolar acid trehalase CU254_RS24380 73f1cd376b0575337aea6ba9b4a64e04 789 Pfam PF03636 Glycosyl hydrolase family 65, N-terminal domain 16 269 2.4E-62 T 28-03-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 CU254_RS24380 73f1cd376b0575337aea6ba9b4a64e04 789 Gene3D G3DSA:1.50.10.10 320 680 1.8E-109 T 28-03-2018 CU254_RS24380 73f1cd376b0575337aea6ba9b4a64e04 789 SUPERFAMILY SSF74650 5 271 1.98E-60 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CU254_RS18725 8d1b82b5359ffc71918690d0eb1dfdb7 486 Gene3D G3DSA:3.50.50.60 6 407 6.6E-22 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS18725 8d1b82b5359ffc71918690d0eb1dfdb7 486 SUPERFAMILY SSF51905 89 195 4.51E-25 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS18725 8d1b82b5359ffc71918690d0eb1dfdb7 486 SUPERFAMILY SSF51905 303 361 4.51E-25 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS18725 8d1b82b5359ffc71918690d0eb1dfdb7 486 SUPERFAMILY SSF51905 7 55 4.51E-25 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS16215 daa380f0d9986819ceaeae2bf45e15c8 217 Gene3D G3DSA:3.40.50.2300 1 133 1.1E-33 T 28-03-2018 CU254_RS16215 daa380f0d9986819ceaeae2bf45e15c8 217 Pfam PF00072 Response regulator receiver domain 4 115 3.3E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS16215 daa380f0d9986819ceaeae2bf45e15c8 217 Gene3D G3DSA:1.10.10.10 134 210 2.0E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS16215 daa380f0d9986819ceaeae2bf45e15c8 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 4.0E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS16215 daa380f0d9986819ceaeae2bf45e15c8 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 4.0E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS16215 daa380f0d9986819ceaeae2bf45e15c8 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 4.0E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS16215 daa380f0d9986819ceaeae2bf45e15c8 217 SUPERFAMILY SSF52172 1 179 1.11E-30 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS16215 daa380f0d9986819ceaeae2bf45e15c8 217 ProSitePatterns PS00622 LuxR-type HTH domain signature. 165 192 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS16215 daa380f0d9986819ceaeae2bf45e15c8 217 SMART SM00448 2 115 2.6E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS16215 daa380f0d9986819ceaeae2bf45e15c8 217 SMART SM00421 148 205 7.7E-23 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS16215 daa380f0d9986819ceaeae2bf45e15c8 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 205 2.1E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS17840 fa531f2539465a6ba00a5d70ef25530e 92 Gene3D G3DSA:3.30.2270.10 1 88 6.3E-39 T 28-03-2018 CU254_RS17840 fa531f2539465a6ba00a5d70ef25530e 92 Pfam PF04267 Sarcosine oxidase, delta subunit family 3 83 2.1E-38 T 28-03-2018 IPR006279 Sarcosine oxidase, delta subunit, heterotetrameric GO:0008115|GO:0046653 KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 CU254_RS17840 fa531f2539465a6ba00a5d70ef25530e 92 TIGRFAM TIGR01374 soxD: sarcosine oxidase, delta subunit family 3 85 2.0E-38 T 28-03-2018 IPR006279 Sarcosine oxidase, delta subunit, heterotetrameric GO:0008115|GO:0046653 KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 CU254_RS04935 e87971cf8c0f53585e901e05cd13bfa1 434 TIGRFAM TIGR02022 hutF: formiminoglutamate deiminase 1 431 9.3E-144 T 28-03-2018 IPR010252 Formiminoglutamate deiminase CU254_RS04935 e87971cf8c0f53585e901e05cd13bfa1 434 SUPERFAMILY SSF51338 363 421 8.1E-10 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS04935 e87971cf8c0f53585e901e05cd13bfa1 434 SUPERFAMILY SSF51556 48 351 2.37E-67 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS04935 e87971cf8c0f53585e901e05cd13bfa1 434 Gene3D G3DSA:3.20.20.140 51 352 4.7E-49 T 28-03-2018 CU254_RS04935 e87971cf8c0f53585e901e05cd13bfa1 434 Gene3D G3DSA:2.30.40.10 1 50 7.4E-6 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS04935 e87971cf8c0f53585e901e05cd13bfa1 434 Pfam PF01979 Amidohydrolase family 47 408 6.7E-42 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CU254_RS29570 8ff69b645a964c1cdfc161a61acc0a15 224 Gene3D G3DSA:1.10.10.10 3 74 2.2E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS29570 8ff69b645a964c1cdfc161a61acc0a15 224 Pfam PF07729 FCD domain 83 204 2.8E-22 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS29570 8ff69b645a964c1cdfc161a61acc0a15 224 SUPERFAMILY SSF46785 5 75 2.4E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS29570 8ff69b645a964c1cdfc161a61acc0a15 224 Gene3D G3DSA:1.20.120.530 75 223 5.8E-23 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS29570 8ff69b645a964c1cdfc161a61acc0a15 224 SMART SM00895 81 207 2.0E-11 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS29570 8ff69b645a964c1cdfc161a61acc0a15 224 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 71 9.4E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS29570 8ff69b645a964c1cdfc161a61acc0a15 224 SMART SM00345 13 71 8.1E-12 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS29570 8ff69b645a964c1cdfc161a61acc0a15 224 SUPERFAMILY SSF48008 83 213 1.46E-15 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS16660 52f883c6e009fe45406b8fa2795a74f7 364 Gene3D G3DSA:1.10.10.10 100 342 5.5E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS16660 52f883c6e009fe45406b8fa2795a74f7 364 Pfam PF13556 PucR C-terminal helix-turn-helix domain 292 349 4.8E-21 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CU254_RS17675 f00bffa022948bbd7a655ba0077c3777 371 Gene3D G3DSA:3.20.20.30 5 371 3.7E-74 T 28-03-2018 CU254_RS17675 f00bffa022948bbd7a655ba0077c3777 371 PIRSF PIRSF000337 287 371 4.1E-15 T 28-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 CU254_RS17675 f00bffa022948bbd7a655ba0077c3777 371 PIRSF PIRSF000337 8 295 8.0E-67 T 28-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 CU254_RS17675 f00bffa022948bbd7a655ba0077c3777 371 SUPERFAMILY SSF51679 8 365 1.15E-83 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS17675 f00bffa022948bbd7a655ba0077c3777 371 Pfam PF00296 Luciferase-like monooxygenase 21 280 8.3E-38 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS05870 7e062d49182c224701a4cc5d45f16c80 248 SUPERFAMILY SSF47336 169 244 3.8E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS05870 7e062d49182c224701a4cc5d45f16c80 248 SMART SM00823 Phosphopantetheine attachment site 175 246 4.4E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS05870 7e062d49182c224701a4cc5d45f16c80 248 Pfam PF00550 Phosphopantetheine attachment site 186 240 1.0E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS05870 7e062d49182c224701a4cc5d45f16c80 248 Gene3D G3DSA:1.10.1200.10 157 248 1.6E-14 T 28-03-2018 CU254_RS40195 3049c595f5e14635e5ed098b0a110c88 333 Pfam PF12079 Protein of unknown function (DUF3558) 16 164 7.2E-11 T 28-03-2018 IPR024520 Protein of unknown function DUF3558 CU254_RS11810 d6dc3f9c5f2cea6c65cf424ad4f1815f 390 SUPERFAMILY SSF101960 33 386 6.02E-88 T 28-03-2018 CU254_RS11810 d6dc3f9c5f2cea6c65cf424ad4f1815f 390 Gene3D G3DSA:3.40.50.1820 70 216 0.0021 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS11810 d6dc3f9c5f2cea6c65cf424ad4f1815f 390 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 106 377 2.3E-77 T 28-03-2018 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 CU254_RS11810 d6dc3f9c5f2cea6c65cf424ad4f1815f 390 Pfam PF01458 Uncharacterized protein family (UPF0051) 141 360 6.4E-72 T 28-03-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 CU254_RS03745 91ccbf8489f761ea89f6b4ae634a7ca0 295 SUPERFAMILY SSF46785 13 118 2.58E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS03745 91ccbf8489f761ea89f6b4ae634a7ca0 295 Pfam PF03466 LysR substrate binding domain 97 292 4.0E-44 T 28-03-2018 IPR005119 LysR, substrate-binding CU254_RS03745 91ccbf8489f761ea89f6b4ae634a7ca0 295 Gene3D G3DSA:3.40.190.10 180 268 1.7E-27 T 28-03-2018 CU254_RS03745 91ccbf8489f761ea89f6b4ae634a7ca0 295 SUPERFAMILY SSF53850 97 294 3.26E-40 T 28-03-2018 CU254_RS03745 91ccbf8489f761ea89f6b4ae634a7ca0 295 Gene3D G3DSA:3.40.190.10 97 179 8.4E-17 T 28-03-2018 CU254_RS03745 91ccbf8489f761ea89f6b4ae634a7ca0 295 Gene3D G3DSA:1.10.10.10 8 94 1.4E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS03745 91ccbf8489f761ea89f6b4ae634a7ca0 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 14 70 2.1E-14 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS11055 f5ce0fa0b9c3b52ed30b0d495beb89a5 420 Pfam PF01612 3'-5' exonuclease 36 199 1.6E-36 T 28-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 CU254_RS11055 f5ce0fa0b9c3b52ed30b0d495beb89a5 420 SUPERFAMILY SSF53098 19 237 7.59E-58 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS11055 f5ce0fa0b9c3b52ed30b0d495beb89a5 420 SMART SM00474 33 200 3.1E-43 T 28-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 CU254_RS11055 f5ce0fa0b9c3b52ed30b0d495beb89a5 420 SUPERFAMILY SSF47819 220 330 5.23E-23 T 28-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 CU254_RS11055 f5ce0fa0b9c3b52ed30b0d495beb89a5 420 SMART SM00341 239 319 2.5E-13 T 28-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 CU254_RS11055 f5ce0fa0b9c3b52ed30b0d495beb89a5 420 Gene3D G3DSA:1.10.150.80 223 339 3.8E-29 T 28-03-2018 CU254_RS11055 f5ce0fa0b9c3b52ed30b0d495beb89a5 420 Pfam PF00570 HRDC domain 243 307 6.2E-14 T 28-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 CU254_RS11055 f5ce0fa0b9c3b52ed30b0d495beb89a5 420 Gene3D G3DSA:3.30.420.10 24 221 8.0E-37 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS24955 75c4a7921fbcbba14394165dbd2b58d0 984 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 391 982 9.0E-226 T 28-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CU254_RS24955 75c4a7921fbcbba14394165dbd2b58d0 984 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 4 983 16.787 T 28-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CU254_RS24955 75c4a7921fbcbba14394165dbd2b58d0 984 SUPERFAMILY SSF50447 657 740 3.12E-23 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CU254_RS24955 75c4a7921fbcbba14394165dbd2b58d0 984 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 3 52 9.9E-15 T 28-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal CU254_RS24955 75c4a7921fbcbba14394165dbd2b58d0 984 PRINTS PR00315 GTP-binding elongation factor signature 535 545 2.3E-9 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CU254_RS24955 75c4a7921fbcbba14394165dbd2b58d0 984 PRINTS PR00315 GTP-binding elongation factor signature 587 596 2.3E-9 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CU254_RS24955 75c4a7921fbcbba14394165dbd2b58d0 984 PRINTS PR00315 GTP-binding elongation factor signature 551 562 2.3E-9 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CU254_RS24955 75c4a7921fbcbba14394165dbd2b58d0 984 PRINTS PR00315 GTP-binding elongation factor signature 483 496 2.3E-9 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CU254_RS24955 75c4a7921fbcbba14394165dbd2b58d0 984 Gene3D G3DSA:2.40.30.10 660 786 4.8E-34 T 28-03-2018 CU254_RS24955 75c4a7921fbcbba14394165dbd2b58d0 984 Pfam PF00009 Elongation factor Tu GTP binding domain 484 644 8.5E-33 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CU254_RS24955 75c4a7921fbcbba14394165dbd2b58d0 984 SUPERFAMILY SSF52156 763 891 8.76E-35 T 28-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 CU254_RS24955 75c4a7921fbcbba14394165dbd2b58d0 984 Gene3D G3DSA:3.40.50.10050 787 863 2.6E-23 T 28-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 CU254_RS24955 75c4a7921fbcbba14394165dbd2b58d0 984 Gene3D G3DSA:3.30.56.50 6 47 2.9E-13 T 28-03-2018 CU254_RS24955 75c4a7921fbcbba14394165dbd2b58d0 984 Gene3D G3DSA:3.30.56.50 400 439 0.063 T 28-03-2018 CU254_RS24955 75c4a7921fbcbba14394165dbd2b58d0 984 SUPERFAMILY SSF52540 480 646 4.35E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS24955 75c4a7921fbcbba14394165dbd2b58d0 984 ProSitePatterns PS01176 Initiation factor 2 signature. 936 958 - T 28-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CU254_RS24955 75c4a7921fbcbba14394165dbd2b58d0 984 Pfam PF11987 Translation-initiation factor 2 772 874 2.4E-32 T 28-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 CU254_RS24955 75c4a7921fbcbba14394165dbd2b58d0 984 Gene3D G3DSA:2.40.30.10 885 984 2.1E-28 T 28-03-2018 CU254_RS24955 75c4a7921fbcbba14394165dbd2b58d0 984 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 482 641 7.8E-33 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CU254_RS24955 75c4a7921fbcbba14394165dbd2b58d0 984 SUPERFAMILY SSF50447 885 983 6.48E-28 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CU254_RS24955 75c4a7921fbcbba14394165dbd2b58d0 984 Gene3D G3DSA:3.40.50.300 474 659 2.5E-38 T 28-03-2018 CU254_RS19595 7d9324e4ec93d3b647dc7a42a7439525 144 SMART SM00347 29 125 7.5E-17 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS19595 7d9324e4ec93d3b647dc7a42a7439525 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 103 3.3E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS19595 7d9324e4ec93d3b647dc7a42a7439525 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 51 67 3.3E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS19595 7d9324e4ec93d3b647dc7a42a7439525 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 83 3.3E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS19595 7d9324e4ec93d3b647dc7a42a7439525 144 Pfam PF01047 MarR family 36 91 2.7E-14 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS19595 7d9324e4ec93d3b647dc7a42a7439525 144 SUPERFAMILY SSF46785 8 135 3.9E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS19595 7d9324e4ec93d3b647dc7a42a7439525 144 Gene3D G3DSA:1.10.10.10 1 137 2.2E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS01450 de9706115d74ad6e1233c2f797146d22 147 SUPERFAMILY SSF46785 2 61 6.17E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS01450 de9706115d74ad6e1233c2f797146d22 147 Pfam PF01037 Lrp/AsnC ligand binding domain 67 138 2.1E-11 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CU254_RS01450 de9706115d74ad6e1233c2f797146d22 147 SMART SM00344 4 108 2.5E-31 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CU254_RS01450 de9706115d74ad6e1233c2f797146d22 147 Gene3D G3DSA:1.10.10.10 3 53 9.0E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS01450 de9706115d74ad6e1233c2f797146d22 147 Pfam PF13404 AsnC-type helix-turn-helix domain 4 41 8.5E-14 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS01450 de9706115d74ad6e1233c2f797146d22 147 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 5.1E-10 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS01450 de9706115d74ad6e1233c2f797146d22 147 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 5.1E-10 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS01450 de9706115d74ad6e1233c2f797146d22 147 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 5.1E-10 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS01450 de9706115d74ad6e1233c2f797146d22 147 Gene3D G3DSA:3.30.70.920 54 135 3.9E-18 T 28-03-2018 CU254_RS01450 de9706115d74ad6e1233c2f797146d22 147 ProSitePatterns PS00519 AsnC-type HTH domain signature. 19 45 - T 28-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site CU254_RS01450 de9706115d74ad6e1233c2f797146d22 147 SUPERFAMILY SSF54909 61 144 1.61E-13 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS21175 85715ba0ff0b9075a182b82931df98d5 181 SUPERFAMILY SSF103256 1 131 1.83E-32 T 28-03-2018 IPR003729 Bifunctional nuclease domain GO:0004518 CU254_RS21175 85715ba0ff0b9075a182b82931df98d5 181 Pfam PF02577 Bifunctional nuclease 6 130 1.5E-35 T 28-03-2018 IPR003729 Bifunctional nuclease domain GO:0004518 CU254_RS34970 3421545047db1367477ae6e6427e8e34 100 Gene3D G3DSA:3.30.280.10 2 99 2.7E-46 T 28-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CU254_RS34970 3421545047db1367477ae6e6427e8e34 100 PIRSF PIRSF001223 1 100 3.6E-48 T 28-03-2018 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CU254_RS34970 3421545047db1367477ae6e6427e8e34 100 ProDom PD002319 SUBUNIT GAMMA HYDROLASE UREASE UREA AMIDOHYDROLASE UREASE ALPHA GAMMA/BETA METAL-BINDING 9 99 6.0E-34 T 28-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CU254_RS34970 3421545047db1367477ae6e6427e8e34 100 SUPERFAMILY SSF54111 1 99 1.96E-42 T 28-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CU254_RS34970 3421545047db1367477ae6e6427e8e34 100 Pfam PF00547 Urease, gamma subunit 1 99 1.0E-45 T 28-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CU254_RS34970 3421545047db1367477ae6e6427e8e34 100 Hamap MF_00739 Urease subunit gamma [ureA]. 1 100 33.184 T 28-03-2018 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CU254_RS34970 3421545047db1367477ae6e6427e8e34 100 TIGRFAM TIGR00193 urease_gam: urease, gamma subunit 1 99 2.7E-44 T 28-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CU254_RS34045 78c834e6e1a6c6b1e7d6a6f1d82a0382 363 Gene3D G3DSA:3.20.20.70 14 362 2.4E-107 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS34045 78c834e6e1a6c6b1e7d6a6f1d82a0382 363 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 15 348 1.0E-63 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CU254_RS34045 78c834e6e1a6c6b1e7d6a6f1d82a0382 363 SUPERFAMILY SSF51395 15 351 1.56E-102 T 28-03-2018 CU254_RS40320 9c3494eac1c2523a7c0235f5568b28c1 407 Pfam PF03275 UDP-galactopyranose mutase 166 373 3.0E-79 T 28-03-2018 IPR015899 UDP-galactopyranose mutase, C-terminal GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 CU254_RS40320 9c3494eac1c2523a7c0235f5568b28c1 407 Pfam PF13450 NAD(P)-binding Rossmann-like domain 22 91 1.1E-17 T 28-03-2018 CU254_RS40320 9c3494eac1c2523a7c0235f5568b28c1 407 Gene3D G3DSA:3.40.50.720 16 310 5.0E-42 T 28-03-2018 CU254_RS40320 9c3494eac1c2523a7c0235f5568b28c1 407 Gene3D G3DSA:3.40.50.720 311 395 2.8E-11 T 28-03-2018 CU254_RS40320 9c3494eac1c2523a7c0235f5568b28c1 407 TIGRFAM TIGR00031 UDP-GALP_mutase: UDP-galactopyranose mutase 18 391 2.3E-104 T 28-03-2018 IPR004379 UDP-galactopyranose mutase GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 CU254_RS40320 9c3494eac1c2523a7c0235f5568b28c1 407 SUPERFAMILY SSF51971 358 387 3.59E-44 T 28-03-2018 CU254_RS40320 9c3494eac1c2523a7c0235f5568b28c1 407 SUPERFAMILY SSF51971 18 284 3.59E-44 T 28-03-2018 CU254_RS40320 9c3494eac1c2523a7c0235f5568b28c1 407 SUPERFAMILY SSF54373 267 337 1.22E-22 T 28-03-2018 CU254_RS23410 85ccb5f92516337d12d831c72c2197c2 279 PRINTS PR00111 Alpha/beta hydrolase fold signature 96 109 6.2E-20 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS23410 85ccb5f92516337d12d831c72c2197c2 279 PRINTS PR00111 Alpha/beta hydrolase fold signature 110 123 6.2E-20 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS23410 85ccb5f92516337d12d831c72c2197c2 279 PRINTS PR00111 Alpha/beta hydrolase fold signature 52 67 6.2E-20 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS23410 85ccb5f92516337d12d831c72c2197c2 279 PRINTS PR00111 Alpha/beta hydrolase fold signature 223 237 6.2E-20 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS23410 85ccb5f92516337d12d831c72c2197c2 279 PRINTS PR00412 Epoxide hydrolase signature 96 109 2.2E-5 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS23410 85ccb5f92516337d12d831c72c2197c2 279 PRINTS PR00412 Epoxide hydrolase signature 254 276 2.2E-5 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS23410 85ccb5f92516337d12d831c72c2197c2 279 PRINTS PR00412 Epoxide hydrolase signature 52 67 2.2E-5 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS23410 85ccb5f92516337d12d831c72c2197c2 279 PRINTS PR00412 Epoxide hydrolase signature 110 123 2.2E-5 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS23410 85ccb5f92516337d12d831c72c2197c2 279 Pfam PF12697 Alpha/beta hydrolase family 26 270 4.2E-21 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS23410 85ccb5f92516337d12d831c72c2197c2 279 SUPERFAMILY SSF53474 13 278 9.25E-59 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS23410 85ccb5f92516337d12d831c72c2197c2 279 Gene3D G3DSA:3.40.50.1820 9 279 2.2E-46 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS15080 57d2debcb3e5dcdc00d563f7b1f5f2b8 321 SUPERFAMILY SSF46785 176 223 6.61E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS15080 57d2debcb3e5dcdc00d563f7b1f5f2b8 321 SUPERFAMILY SSF54909 65 139 2.95E-6 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS15080 57d2debcb3e5dcdc00d563f7b1f5f2b8 321 Gene3D G3DSA:1.10.10.10 2 39 5.1E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS15080 57d2debcb3e5dcdc00d563f7b1f5f2b8 321 Gene3D G3DSA:3.30.70.920 82 141 1.3E-6 T 28-03-2018 CU254_RS15080 57d2debcb3e5dcdc00d563f7b1f5f2b8 321 SUPERFAMILY SSF46785 5 52 1.52E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS15080 57d2debcb3e5dcdc00d563f7b1f5f2b8 321 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 204 223 6.7E-8 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS15080 57d2debcb3e5dcdc00d563f7b1f5f2b8 321 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 193 204 6.7E-8 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS15080 57d2debcb3e5dcdc00d563f7b1f5f2b8 321 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 177 193 6.7E-8 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS15080 57d2debcb3e5dcdc00d563f7b1f5f2b8 321 SUPERFAMILY SSF54909 239 316 1.01E-10 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS15080 57d2debcb3e5dcdc00d563f7b1f5f2b8 321 Gene3D G3DSA:1.10.10.10 174 208 5.7E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS15080 57d2debcb3e5dcdc00d563f7b1f5f2b8 321 Gene3D G3DSA:3.30.70.920 242 320 3.4E-17 T 28-03-2018 CU254_RS15080 57d2debcb3e5dcdc00d563f7b1f5f2b8 321 Pfam PF13404 AsnC-type helix-turn-helix domain 177 218 1.4E-12 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS15080 57d2debcb3e5dcdc00d563f7b1f5f2b8 321 Pfam PF13404 AsnC-type helix-turn-helix domain 6 46 1.6E-15 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS15080 57d2debcb3e5dcdc00d563f7b1f5f2b8 321 SMART SM00344 5 109 8.8E-5 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CU254_RS15080 57d2debcb3e5dcdc00d563f7b1f5f2b8 321 SMART SM00344 177 282 6.3E-9 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CU254_RS15080 57d2debcb3e5dcdc00d563f7b1f5f2b8 321 Gene3D G3DSA:1.10.10.10 209 241 0.057 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS15080 57d2debcb3e5dcdc00d563f7b1f5f2b8 321 Pfam PF01037 Lrp/AsnC ligand binding domain 245 313 3.2E-11 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CU254_RS15080 57d2debcb3e5dcdc00d563f7b1f5f2b8 321 Gene3D G3DSA:1.10.10.10 40 81 0.34 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS27495 05c52e6a6189f5ddfd7778b660bf65b8 263 Gene3D G3DSA:3.60.15.10 1 235 1.8E-27 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS27495 05c52e6a6189f5ddfd7778b660bf65b8 263 SMART SM00849 19 213 7.8E-19 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS27495 05c52e6a6189f5ddfd7778b660bf65b8 263 Pfam PF00753 Metallo-beta-lactamase superfamily 24 213 2.6E-13 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS27495 05c52e6a6189f5ddfd7778b660bf65b8 263 SUPERFAMILY SSF56281 1 261 2.38E-46 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS16545 1289af983ec49ff9834eb1207ee9a1b4 349 SUPERFAMILY SSF52172 255 327 3.88E-9 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS16545 1289af983ec49ff9834eb1207ee9a1b4 349 SUPERFAMILY SSF55781 124 265 1.33E-16 T 28-03-2018 IPR029016 GAF domain-like CU254_RS16545 1289af983ec49ff9834eb1207ee9a1b4 349 Pfam PF13185 GAF domain 119 263 4.0E-14 T 28-03-2018 IPR003018 GAF domain GO:0005515 CU254_RS16545 1289af983ec49ff9834eb1207ee9a1b4 349 SMART SM01012 275 330 2.1E-21 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 CU254_RS16545 1289af983ec49ff9834eb1207ee9a1b4 349 Gene3D G3DSA:3.30.450.40 106 286 4.9E-22 T 28-03-2018 IPR029016 GAF domain-like CU254_RS16545 1289af983ec49ff9834eb1207ee9a1b4 349 Pfam PF03861 ANTAR domain 277 326 1.3E-20 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 CU254_RS16545 1289af983ec49ff9834eb1207ee9a1b4 349 Gene3D G3DSA:1.10.10.10 287 331 5.0E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS37865 405baba9234802d3f369b135e4dd307b 388 Pfam PF00155 Aminotransferase class I and II 37 381 1.3E-53 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CU254_RS37865 405baba9234802d3f369b135e4dd307b 388 SUPERFAMILY SSF53383 14 387 2.93E-94 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS37865 405baba9234802d3f369b135e4dd307b 388 Gene3D G3DSA:3.90.1150.10 268 388 9.8E-27 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS37865 405baba9234802d3f369b135e4dd307b 388 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 233 246 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CU254_RS37865 405baba9234802d3f369b135e4dd307b 388 Gene3D G3DSA:3.40.640.10 51 267 1.5E-46 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS30955 e7fab5942ecb307638fc04da8df3428e 255 SUPERFAMILY SSF56281 2 250 2.03E-46 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS30955 e7fab5942ecb307638fc04da8df3428e 255 Gene3D G3DSA:3.60.15.10 1 254 1.4E-42 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS30955 e7fab5942ecb307638fc04da8df3428e 255 SMART SM00849 18 205 0.0089 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS30955 e7fab5942ecb307638fc04da8df3428e 255 Pfam PF12706 Beta-lactamase superfamily domain 47 224 9.4E-24 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS37895 6a86c46a13346b051a4da2e597920b28 129 Pfam PF00934 PE family 23 114 2.6E-5 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CU254_RS37895 6a86c46a13346b051a4da2e597920b28 129 Gene3D G3DSA:1.10.287.1060 19 122 8.1E-6 T 28-03-2018 CU254_RS16805 f8faa79ada77fb23d10076faa63f14f5 214 Pfam PF12840 Helix-turn-helix domain 7 61 3.3E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS16805 f8faa79ada77fb23d10076faa63f14f5 214 Gene3D G3DSA:1.10.10.10 2 89 4.2E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS16805 f8faa79ada77fb23d10076faa63f14f5 214 SUPERFAMILY SSF46785 5 188 3.11E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS05490 04949b28f8d17b2a8e26ffce924910ef 359 SUPERFAMILY SSF55874 259 343 1.0E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS05490 04949b28f8d17b2a8e26ffce924910ef 359 Gene3D G3DSA:3.30.565.10 235 359 2.0E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS05490 04949b28f8d17b2a8e26ffce924910ef 359 Pfam PF07730 Histidine kinase 158 223 3.7E-13 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CU254_RS17835 2f62faf9aaa06ce5010219714bf9fb14 414 Pfam PF01266 FAD dependent oxidoreductase 32 378 3.8E-58 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CU254_RS17835 2f62faf9aaa06ce5010219714bf9fb14 414 Gene3D G3DSA:3.50.50.60 333 411 2.5E-6 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS17835 2f62faf9aaa06ce5010219714bf9fb14 414 TIGRFAM TIGR01373 soxB: sarcosine oxidase, beta subunit family 21 406 5.3E-189 T 28-03-2018 IPR006278 Sarcosine oxidase subunit beta GO:0008115|GO:0046653|GO:0055114 KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 CU254_RS17835 2f62faf9aaa06ce5010219714bf9fb14 414 SUPERFAMILY SSF51905 342 402 6.8E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS17835 2f62faf9aaa06ce5010219714bf9fb14 414 SUPERFAMILY SSF51905 31 252 6.8E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS17835 2f62faf9aaa06ce5010219714bf9fb14 414 Gene3D G3DSA:3.30.9.10 113 194 4.6E-8 T 28-03-2018 CU254_RS17835 2f62faf9aaa06ce5010219714bf9fb14 414 Gene3D G3DSA:3.30.9.10 195 332 9.6E-30 T 28-03-2018 CU254_RS17835 2f62faf9aaa06ce5010219714bf9fb14 414 Gene3D G3DSA:3.50.50.60 3 90 2.6E-4 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS17835 2f62faf9aaa06ce5010219714bf9fb14 414 SUPERFAMILY SSF54373 260 339 3.34E-6 T 28-03-2018 CU254_RS03430 22f43d4db3272227679dcf0a5e4a8f71 385 Gene3D G3DSA:1.20.140.10 223 385 3.8E-60 T 28-03-2018 CU254_RS03430 22f43d4db3272227679dcf0a5e4a8f71 385 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 126 138 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CU254_RS03430 22f43d4db3272227679dcf0a5e4a8f71 385 SUPERFAMILY SSF56645 7 245 3.14E-76 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS03430 22f43d4db3272227679dcf0a5e4a8f71 385 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 341 360 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CU254_RS03430 22f43d4db3272227679dcf0a5e4a8f71 385 Gene3D G3DSA:2.40.110.10 123 222 1.0E-39 T 28-03-2018 CU254_RS03430 22f43d4db3272227679dcf0a5e4a8f71 385 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 124 221 8.4E-30 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CU254_RS03430 22f43d4db3272227679dcf0a5e4a8f71 385 Gene3D G3DSA:1.10.540.10 5 121 8.0E-31 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS03430 22f43d4db3272227679dcf0a5e4a8f71 385 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 10 120 3.3E-28 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS03430 22f43d4db3272227679dcf0a5e4a8f71 385 PIRSF PIRSF016578 128 384 1.9E-16 T 28-03-2018 CU254_RS03430 22f43d4db3272227679dcf0a5e4a8f71 385 PIRSF PIRSF016578 5 93 2.2E-4 T 28-03-2018 CU254_RS03430 22f43d4db3272227679dcf0a5e4a8f71 385 SUPERFAMILY SSF47203 231 384 2.26E-57 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS03430 22f43d4db3272227679dcf0a5e4a8f71 385 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 233 383 7.4E-49 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS21165 7aedd769de12b7a102bae01c2d5236eb 275 Gene3D G3DSA:3.20.20.30 2 267 5.3E-50 T 28-03-2018 CU254_RS21165 7aedd769de12b7a102bae01c2d5236eb 275 SUPERFAMILY SSF51679 1 232 5.89E-44 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS21165 7aedd769de12b7a102bae01c2d5236eb 275 Pfam PF00296 Luciferase-like monooxygenase 19 223 1.0E-39 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS09455 ebae3c111bf308092f8eafc9468a99a2 491 Pfam PF01593 Flavin containing amine oxidoreductase 18 488 2.3E-36 T 28-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 CU254_RS09455 ebae3c111bf308092f8eafc9468a99a2 491 Gene3D G3DSA:3.50.50.60 10 491 7.8E-33 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS09455 ebae3c111bf308092f8eafc9468a99a2 491 TIGRFAM TIGR02734 crtI_fam: phytoene desaturase 11 490 3.4E-147 T 28-03-2018 IPR014105 Carotenoid/retinoid oxidoreductase GO:0016117|GO:0055114 CU254_RS09455 ebae3c111bf308092f8eafc9468a99a2 491 ProSitePatterns PS00982 Bacterial-type phytoene dehydrogenase signature. 460 480 - T 28-03-2018 IPR008150 Phytoene dehydrogenase, bacterial-type, conserved site CU254_RS09455 ebae3c111bf308092f8eafc9468a99a2 491 SUPERFAMILY SSF51905 454 489 1.87E-60 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS09455 ebae3c111bf308092f8eafc9468a99a2 491 SUPERFAMILY SSF51905 10 319 1.87E-60 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS15230 da9277c1218d6fdfce117faf6d91b67b 343 Pfam PF00296 Luciferase-like monooxygenase 18 308 1.7E-49 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS15230 da9277c1218d6fdfce117faf6d91b67b 343 SUPERFAMILY SSF51679 15 332 2.88E-51 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS15230 da9277c1218d6fdfce117faf6d91b67b 343 Gene3D G3DSA:3.20.20.30 4 336 1.1E-49 T 28-03-2018 CU254_RS04135 e8c3d32c6357fc869f1b7098b50a9eea 316 PIRSF PIRSF002849 1 316 1.2E-127 T 28-03-2018 CU254_RS04135 e8c3d32c6357fc869f1b7098b50a9eea 316 SUPERFAMILY SSF52540 4 292 4.51E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS04135 e8c3d32c6357fc869f1b7098b50a9eea 316 Gene3D G3DSA:3.40.50.300 19 185 6.6E-28 T 28-03-2018 CU254_RS04135 e8c3d32c6357fc869f1b7098b50a9eea 316 Gene3D G3DSA:1.10.8.300 204 312 6.5E-34 T 28-03-2018 CU254_RS04135 e8c3d32c6357fc869f1b7098b50a9eea 316 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 38 168 4.1E-64 T 28-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 CU254_RS39535 e6bbb50b4224998afb19949c6441a6f6 682 SUPERFAMILY SSF52540 40 240 9.42E-15 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS39535 e6bbb50b4224998afb19949c6441a6f6 682 Gene3D G3DSA:1.25.40.10 402 673 2.4E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS39535 e6bbb50b4224998afb19949c6441a6f6 682 SUPERFAMILY SSF48452 420 581 1.14E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS25380 c5753c100ee7379c42813c097ce2b4eb 264 Pfam PF01614 Bacterial transcriptional regulator 133 253 4.6E-22 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal CU254_RS25380 c5753c100ee7379c42813c097ce2b4eb 264 SUPERFAMILY SSF55781 94 257 5.23E-39 T 28-03-2018 IPR029016 GAF domain-like CU254_RS25380 c5753c100ee7379c42813c097ce2b4eb 264 Gene3D G3DSA:1.10.10.10 2 75 5.9E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS25380 c5753c100ee7379c42813c097ce2b4eb 264 SUPERFAMILY SSF46785 15 85 9.4E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS25380 c5753c100ee7379c42813c097ce2b4eb 264 Gene3D G3DSA:3.30.450.40 89 261 2.2E-40 T 28-03-2018 IPR029016 GAF domain-like CU254_RS25380 c5753c100ee7379c42813c097ce2b4eb 264 SMART SM00346 14 104 2.7E-8 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS25380 c5753c100ee7379c42813c097ce2b4eb 264 Pfam PF09339 IclR helix-turn-helix domain 17 67 2.2E-13 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS32050 e99839086954899ee0543d262a5e9bf9 723 Gene3D G3DSA:1.10.1040.10 633 723 2.9E-16 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CU254_RS32050 e99839086954899ee0543d262a5e9bf9 723 Gene3D G3DSA:3.90.226.10 1 276 3.8E-55 T 28-03-2018 CU254_RS32050 e99839086954899ee0543d262a5e9bf9 723 SUPERFAMILY SSF52096 1 303 1.79E-62 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS32050 e99839086954899ee0543d262a5e9bf9 723 SUPERFAMILY SSF51735 320 502 1.53E-57 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS32050 e99839086954899ee0543d262a5e9bf9 723 Gene3D G3DSA:3.40.50.720 277 502 4.4E-61 T 28-03-2018 CU254_RS32050 e99839086954899ee0543d262a5e9bf9 723 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 323 501 2.1E-61 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CU254_RS32050 e99839086954899ee0543d262a5e9bf9 723 Gene3D G3DSA:1.10.1040.10 503 609 4.8E-14 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CU254_RS32050 e99839086954899ee0543d262a5e9bf9 723 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 504 604 2.3E-18 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CU254_RS32050 e99839086954899ee0543d262a5e9bf9 723 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 206 3.5E-35 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CU254_RS32050 e99839086954899ee0543d262a5e9bf9 723 SUPERFAMILY SSF48179 503 645 9.35E-17 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CU254_RS32050 e99839086954899ee0543d262a5e9bf9 723 SUPERFAMILY SSF48179 631 720 4.25E-16 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CU254_RS07460 9b044abae77d310adc95485750cdcb6a 284 SUPERFAMILY SSF56529 64 281 1.44E-75 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CU254_RS07460 9b044abae77d310adc95485750cdcb6a 284 Gene3D G3DSA:3.90.850.10 43 284 7.9E-80 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CU254_RS07460 9b044abae77d310adc95485750cdcb6a 284 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 74 280 2.1E-70 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CU254_RS27600 c911448810618d004ed842379e5b06b5 346 SUPERFAMILY SSF53822 130 344 2.94E-47 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CU254_RS27600 c911448810618d004ed842379e5b06b5 346 Gene3D G3DSA:3.40.50.2300 66 176 2.0E-20 T 28-03-2018 CU254_RS27600 c911448810618d004ed842379e5b06b5 346 SUPERFAMILY SSF47413 7 67 5.63E-13 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS27600 c911448810618d004ed842379e5b06b5 346 Pfam PF00356 Bacterial regulatory proteins, lacI family 10 52 5.4E-11 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CU254_RS27600 c911448810618d004ed842379e5b06b5 346 Gene3D G3DSA:1.10.10.10 1 23 2.4E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS27600 c911448810618d004ed842379e5b06b5 346 SMART SM00354 8 79 1.9E-14 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CU254_RS27600 c911448810618d004ed842379e5b06b5 346 Pfam PF13377 Periplasmic binding protein-like domain 178 343 1.0E-38 T 28-03-2018 CU254_RS27600 c911448810618d004ed842379e5b06b5 346 Gene3D G3DSA:1.10.260.40 24 65 2.6E-18 T 28-03-2018 CU254_RS27600 c911448810618d004ed842379e5b06b5 346 Gene3D G3DSA:3.40.50.2300 177 346 2.3E-49 T 28-03-2018 CU254_RS16165 7af154d9c7db7bf34ef63db901d837db 845 SUPERFAMILY SSF48452 504 611 9.11E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS16165 7af154d9c7db7bf34ef63db901d837db 845 Gene3D G3DSA:1.10.10.10 790 844 5.8E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS16165 7af154d9c7db7bf34ef63db901d837db 845 Gene3D G3DSA:1.25.40.10 259 458 1.9E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS16165 7af154d9c7db7bf34ef63db901d837db 845 SUPERFAMILY SSF52540 4 166 1.97E-8 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS16165 7af154d9c7db7bf34ef63db901d837db 845 Gene3D G3DSA:3.40.50.300 3 128 1.9E-5 T 28-03-2018 CU254_RS16165 7af154d9c7db7bf34ef63db901d837db 845 Pfam PF00196 Bacterial regulatory proteins, luxR family 788 841 1.8E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS16165 7af154d9c7db7bf34ef63db901d837db 845 SMART SM00421 786 843 2.0E-21 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS16165 7af154d9c7db7bf34ef63db901d837db 845 SUPERFAMILY SSF46894 786 843 1.02E-16 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS16165 7af154d9c7db7bf34ef63db901d837db 845 Gene3D G3DSA:1.25.40.10 459 625 9.5E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS16165 7af154d9c7db7bf34ef63db901d837db 845 Gene3D G3DSA:1.25.40.10 636 789 4.1E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS16165 7af154d9c7db7bf34ef63db901d837db 845 ProSitePatterns PS00622 LuxR-type HTH domain signature. 803 830 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS16165 7af154d9c7db7bf34ef63db901d837db 845 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 803 819 1.1E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS16165 7af154d9c7db7bf34ef63db901d837db 845 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 819 831 1.1E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS16165 7af154d9c7db7bf34ef63db901d837db 845 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 789 803 1.1E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS34815 1e00b9bdf7fb28bbf8017b18811fa078 438 PIRSF PIRSF001369 46 438 1.1E-155 T 28-03-2018 IPR024176 Citrate synthase, bacterial-type CU254_RS34815 1e00b9bdf7fb28bbf8017b18811fa078 438 Pfam PF00285 Citrate synthase, C-terminal domain 55 421 5.2E-134 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CU254_RS34815 1e00b9bdf7fb28bbf8017b18811fa078 438 Gene3D G3DSA:1.10.580.10 62 291 9.7E-81 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain CU254_RS34815 1e00b9bdf7fb28bbf8017b18811fa078 438 SUPERFAMILY SSF48256 13 438 1.83E-156 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CU254_RS34815 1e00b9bdf7fb28bbf8017b18811fa078 438 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 23 432 7.9E-176 T 28-03-2018 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 CU254_RS34815 1e00b9bdf7fb28bbf8017b18811fa078 438 PRINTS PR00143 Citrate synthase signature 250 278 6.6E-54 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CU254_RS34815 1e00b9bdf7fb28bbf8017b18811fa078 438 PRINTS PR00143 Citrate synthase signature 174 187 6.6E-54 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CU254_RS34815 1e00b9bdf7fb28bbf8017b18811fa078 438 PRINTS PR00143 Citrate synthase signature 389 403 6.6E-54 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CU254_RS34815 1e00b9bdf7fb28bbf8017b18811fa078 438 PRINTS PR00143 Citrate synthase signature 228 243 6.6E-54 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CU254_RS34815 1e00b9bdf7fb28bbf8017b18811fa078 438 PRINTS PR00143 Citrate synthase signature 369 385 6.6E-54 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CU254_RS34815 1e00b9bdf7fb28bbf8017b18811fa078 438 PRINTS PR00143 Citrate synthase signature 306 326 6.6E-54 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CU254_RS34815 1e00b9bdf7fb28bbf8017b18811fa078 438 ProSitePatterns PS00480 Citrate synthase signature. 313 325 - T 28-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 CU254_RS34815 1e00b9bdf7fb28bbf8017b18811fa078 438 Gene3D G3DSA:1.10.230.10 292 389 8.4E-34 T 28-03-2018 IPR016143 Citrate synthase-like, small alpha subdomain CU254_RS31440 30efdc40fceba25c491cc938f4578d2b 484 Pfam PF00085 Thioredoxin 54 151 1.9E-8 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 CU254_RS31440 30efdc40fceba25c491cc938f4578d2b 484 Pfam PF00085 Thioredoxin 288 381 3.0E-12 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 CU254_RS31440 30efdc40fceba25c491cc938f4578d2b 484 SUPERFAMILY SSF52833 48 156 8.81E-18 T 28-03-2018 IPR012336 Thioredoxin-like fold CU254_RS31440 30efdc40fceba25c491cc938f4578d2b 484 Gene3D G3DSA:3.40.30.10 49 170 2.8E-17 T 28-03-2018 CU254_RS31440 30efdc40fceba25c491cc938f4578d2b 484 Gene3D G3DSA:3.40.30.10 277 479 2.2E-20 T 28-03-2018 CU254_RS31440 30efdc40fceba25c491cc938f4578d2b 484 SUPERFAMILY SSF52833 279 394 6.86E-20 T 28-03-2018 IPR012336 Thioredoxin-like fold CU254_RS23020 ee32c763f368e8e23aa370e55d2e7b03 201 SMART SM00448 2 115 1.7E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS23020 ee32c763f368e8e23aa370e55d2e7b03 201 Pfam PF00196 Bacterial regulatory proteins, luxR family 140 195 1.3E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS23020 ee32c763f368e8e23aa370e55d2e7b03 201 SMART SM00421 138 195 6.2E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS23020 ee32c763f368e8e23aa370e55d2e7b03 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 141 155 2.0E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS23020 ee32c763f368e8e23aa370e55d2e7b03 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 183 2.0E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS23020 ee32c763f368e8e23aa370e55d2e7b03 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 171 2.0E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS23020 ee32c763f368e8e23aa370e55d2e7b03 201 Gene3D G3DSA:1.10.10.10 127 201 6.8E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS23020 ee32c763f368e8e23aa370e55d2e7b03 201 Gene3D G3DSA:3.40.50.2300 1 126 7.2E-34 T 28-03-2018 CU254_RS23020 ee32c763f368e8e23aa370e55d2e7b03 201 SUPERFAMILY SSF52172 2 130 2.28E-30 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS23020 ee32c763f368e8e23aa370e55d2e7b03 201 Pfam PF00072 Response regulator receiver domain 4 116 1.2E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS23020 ee32c763f368e8e23aa370e55d2e7b03 201 SUPERFAMILY SSF46894 129 201 9.52E-18 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS13245 8ba60421019d33a5647ab3eba5b9cd5d 430 ProSitePatterns PS00217 Sugar transport proteins signature 2. 119 144 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CU254_RS13245 8ba60421019d33a5647ab3eba5b9cd5d 430 Pfam PF00083 Sugar (and other) transporter 258 400 9.7E-11 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CU254_RS13245 8ba60421019d33a5647ab3eba5b9cd5d 430 SUPERFAMILY SSF103473 12 414 2.75E-69 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS13245 8ba60421019d33a5647ab3eba5b9cd5d 430 Gene3D G3DSA:1.20.1250.20 214 417 1.1E-19 T 28-03-2018 CU254_RS13245 8ba60421019d33a5647ab3eba5b9cd5d 430 Gene3D G3DSA:1.20.1250.20 14 213 4.4E-33 T 28-03-2018 CU254_RS13245 8ba60421019d33a5647ab3eba5b9cd5d 430 Pfam PF07690 Major Facilitator Superfamily 29 244 2.9E-27 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS07855 d03d740276568da9695d793c950811f3 339 Gene3D G3DSA:2.60.120.260 179 325 1.1E-44 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS07855 d03d740276568da9695d793c950811f3 339 Gene3D G3DSA:2.60.120.260 1 175 8.2E-59 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS07855 d03d740276568da9695d793c950811f3 339 SUPERFAMILY SSF49785 183 322 1.06E-39 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS07855 d03d740276568da9695d793c950811f3 339 Hamap MF_00813 Probable allantoicase [alc]. 5 323 41.168 T 28-03-2018 IPR005164 Allantoicase GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 CU254_RS07855 d03d740276568da9695d793c950811f3 339 Pfam PF03561 Allantoicase repeat 23 170 4.8E-41 T 28-03-2018 IPR015908 Allantoicase domain GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 CU254_RS07855 d03d740276568da9695d793c950811f3 339 Pfam PF03561 Allantoicase repeat 192 320 9.6E-35 T 28-03-2018 IPR015908 Allantoicase domain GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 CU254_RS07855 d03d740276568da9695d793c950811f3 339 PIRSF PIRSF016516 2 273 3.4E-75 T 28-03-2018 IPR005164 Allantoicase GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 CU254_RS07855 d03d740276568da9695d793c950811f3 339 PIRSF PIRSF016516 263 336 2.7E-13 T 28-03-2018 IPR005164 Allantoicase GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 CU254_RS07855 d03d740276568da9695d793c950811f3 339 TIGRFAM TIGR02961 allantoicase: allantoicase 15 321 8.7E-109 T 28-03-2018 IPR005164 Allantoicase GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 CU254_RS07855 d03d740276568da9695d793c950811f3 339 SUPERFAMILY SSF49785 12 174 1.15E-50 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS40070 7eaf69a0d0638d33af1fbaa633e413c1 379 Pfam PF06441 Epoxide hydrolase N terminus 11 113 7.1E-31 T 28-03-2018 IPR010497 Epoxide hydrolase, N-terminal KEGG: 00980+3.3.2.9|Reactome: R-HSA-211945 CU254_RS40070 7eaf69a0d0638d33af1fbaa633e413c1 379 PIRSF PIRSF001112 2 378 6.7E-91 T 28-03-2018 IPR016292 Epoxide hydrolase GO:0033961 KEGG: 00980+3.3.2.9|Reactome: R-HSA-211945 CU254_RS40070 7eaf69a0d0638d33af1fbaa633e413c1 379 PRINTS PR00412 Epoxide hydrolase signature 105 123 3.3E-12 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS40070 7eaf69a0d0638d33af1fbaa633e413c1 379 PRINTS PR00412 Epoxide hydrolase signature 193 206 3.3E-12 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS40070 7eaf69a0d0638d33af1fbaa633e413c1 379 PRINTS PR00412 Epoxide hydrolase signature 179 192 3.3E-12 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS40070 7eaf69a0d0638d33af1fbaa633e413c1 379 PRINTS PR00412 Epoxide hydrolase signature 134 149 3.3E-12 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS40070 7eaf69a0d0638d33af1fbaa633e413c1 379 PRINTS PR00412 Epoxide hydrolase signature 352 374 3.3E-12 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS40070 7eaf69a0d0638d33af1fbaa633e413c1 379 SUPERFAMILY SSF53474 4 377 8.37E-81 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS40070 7eaf69a0d0638d33af1fbaa633e413c1 379 Gene3D G3DSA:3.40.50.1820 1 379 4.3E-68 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS24400 8757ee411e31b2b377d829b461557108 633 Pfam PF09298 Fumarylacetoacetase N-terminal 250 340 2.2E-17 T 28-03-2018 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 CU254_RS24400 8757ee411e31b2b377d829b461557108 633 TIGRFAM TIGR01266 fum_ac_acetase: fumarylacetoacetase 237 631 2.7E-126 T 28-03-2018 IPR005959 Fumarylacetoacetase GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 CU254_RS24400 8757ee411e31b2b377d829b461557108 633 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 346 629 4.0E-51 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CU254_RS24400 8757ee411e31b2b377d829b461557108 633 Gene3D G3DSA:2.30.30.230 236 337 2.1E-25 T 28-03-2018 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 CU254_RS24400 8757ee411e31b2b377d829b461557108 633 SUPERFAMILY SSF63433 236 340 1.83E-23 T 28-03-2018 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 CU254_RS24400 8757ee411e31b2b377d829b461557108 633 Gene3D G3DSA:3.90.850.10 338 616 7.5E-77 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CU254_RS24400 8757ee411e31b2b377d829b461557108 633 SUPERFAMILY SSF56529 342 629 2.75E-84 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CU254_RS04375 6afc6dac90bbd253d0869983d220b537 471 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 246 253 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CU254_RS04375 6afc6dac90bbd253d0869983d220b537 471 Gene3D G3DSA:3.40.605.10 1 264 1.0E-95 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CU254_RS04375 6afc6dac90bbd253d0869983d220b537 471 Pfam PF00171 Aldehyde dehydrogenase family 14 467 3.1E-158 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CU254_RS04375 6afc6dac90bbd253d0869983d220b537 471 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 274 285 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CU254_RS04375 6afc6dac90bbd253d0869983d220b537 471 SUPERFAMILY SSF53720 3 468 1.28E-156 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CU254_RS04375 6afc6dac90bbd253d0869983d220b537 471 Gene3D G3DSA:3.40.309.10 265 453 1.5E-67 T 28-03-2018 CU254_RS08625 b2736adc507263f7c19c90b0f5c9a61c 394 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 206 226 - T 28-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CU254_RS08625 b2736adc507263f7c19c90b0f5c9a61c 394 SUPERFAMILY SSF53383 5 392 2.28E-86 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS08625 b2736adc507263f7c19c90b0f5c9a61c 394 Pfam PF00266 Aminotransferase class-V 23 385 6.2E-64 T 28-03-2018 IPR000192 Aminotransferase class V domain CU254_RS08625 b2736adc507263f7c19c90b0f5c9a61c 394 Gene3D G3DSA:3.90.1150.10 273 392 3.3E-25 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS08625 b2736adc507263f7c19c90b0f5c9a61c 394 Gene3D G3DSA:3.40.640.10 31 272 1.7E-46 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS31875 4c51070215bdad695a1374c2102eb10b 251 SUPERFAMILY SSF46785 13 82 1.85E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS31875 4c51070215bdad695a1374c2102eb10b 251 Pfam PF01614 Bacterial transcriptional regulator 129 243 9.6E-8 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal CU254_RS31875 4c51070215bdad695a1374c2102eb10b 251 SUPERFAMILY SSF55781 86 245 8.5E-33 T 28-03-2018 IPR029016 GAF domain-like CU254_RS31875 4c51070215bdad695a1374c2102eb10b 251 Gene3D G3DSA:1.10.10.10 5 80 1.9E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS31875 4c51070215bdad695a1374c2102eb10b 251 Pfam PF09339 IclR helix-turn-helix domain 17 63 3.2E-8 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS31875 4c51070215bdad695a1374c2102eb10b 251 SMART SM00346 12 101 1.9E-9 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS31875 4c51070215bdad695a1374c2102eb10b 251 Gene3D G3DSA:3.30.450.40 81 248 3.2E-33 T 28-03-2018 IPR029016 GAF domain-like CU254_RS24680 617a3d37d56d35194e45a464ecd95019 405 SUPERFAMILY SSF56672 12 252 3.2E-78 T 28-03-2018 CU254_RS24680 617a3d37d56d35194e45a464ecd95019 405 Pfam PF11798 IMS family HHH motif 187 213 2.2E-7 T 28-03-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 CU254_RS24680 617a3d37d56d35194e45a464ecd95019 405 Gene3D G3DSA:1.10.150.20 188 260 8.9E-23 T 28-03-2018 CU254_RS24680 617a3d37d56d35194e45a464ecd95019 405 Gene3D G3DSA:3.30.1490.100 261 370 3.6E-29 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CU254_RS24680 617a3d37d56d35194e45a464ecd95019 405 Pfam PF00817 impB/mucB/samB family 24 170 2.7E-44 T 28-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CU254_RS24680 617a3d37d56d35194e45a464ecd95019 405 Gene3D G3DSA:3.30.70.270 57 131 3.2E-22 T 28-03-2018 CU254_RS24680 617a3d37d56d35194e45a464ecd95019 405 Gene3D G3DSA:3.30.70.270 132 187 1.8E-14 T 28-03-2018 CU254_RS24680 617a3d37d56d35194e45a464ecd95019 405 SUPERFAMILY SSF100879 258 355 2.55E-27 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CU254_RS24680 617a3d37d56d35194e45a464ecd95019 405 Pfam PF11799 impB/mucB/samB family C-terminal domain 252 363 8.8E-18 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CU254_RS24680 617a3d37d56d35194e45a464ecd95019 405 Hamap MF_01113 DNA polymerase IV [dinB]. 18 368 35.126 T 28-03-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 CU254_RS36360 c4b6f1edb2893c934a893e2470a61ab0 323 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 11 305 19.283 T 28-03-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CU254_RS36360 c4b6f1edb2893c934a893e2470a61ab0 323 Pfam PF01171 PP-loop family 24 197 1.4E-33 T 28-03-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 CU254_RS36360 c4b6f1edb2893c934a893e2470a61ab0 323 Gene3D G3DSA:3.40.50.620 21 250 3.0E-33 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS36360 c4b6f1edb2893c934a893e2470a61ab0 323 SUPERFAMILY SSF82829 211 310 1.31E-17 T 28-03-2018 CU254_RS36360 c4b6f1edb2893c934a893e2470a61ab0 323 SUPERFAMILY SSF52402 22 230 3.45E-45 T 28-03-2018 CU254_RS36360 c4b6f1edb2893c934a893e2470a61ab0 323 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 24 201 2.0E-37 T 28-03-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CU254_RS36360 c4b6f1edb2893c934a893e2470a61ab0 323 Pfam PF09179 TilS substrate binding domain 246 311 4.6E-15 T 28-03-2018 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CU254_RS16490 0fc265ba88e513841fed0b8c65484bbb 609 Gene3D G3DSA:2.60.120.260 378 500 3.5E-38 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS16490 0fc265ba88e513841fed0b8c65484bbb 609 PRINTS PR00742 Glycosyl hydrolase family 35 signature 43 60 9.4E-54 T 28-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CU254_RS16490 0fc265ba88e513841fed0b8c65484bbb 609 PRINTS PR00742 Glycosyl hydrolase family 35 signature 296 311 9.4E-54 T 28-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CU254_RS16490 0fc265ba88e513841fed0b8c65484bbb 609 PRINTS PR00742 Glycosyl hydrolase family 35 signature 323 339 9.4E-54 T 28-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CU254_RS16490 0fc265ba88e513841fed0b8c65484bbb 609 PRINTS PR00742 Glycosyl hydrolase family 35 signature 552 568 9.4E-54 T 28-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CU254_RS16490 0fc265ba88e513841fed0b8c65484bbb 609 PRINTS PR00742 Glycosyl hydrolase family 35 signature 260 275 9.4E-54 T 28-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CU254_RS16490 0fc265ba88e513841fed0b8c65484bbb 609 PRINTS PR00742 Glycosyl hydrolase family 35 signature 174 189 9.4E-54 T 28-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CU254_RS16490 0fc265ba88e513841fed0b8c65484bbb 609 PRINTS PR00742 Glycosyl hydrolase family 35 signature 119 138 9.4E-54 T 28-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CU254_RS16490 0fc265ba88e513841fed0b8c65484bbb 609 PRINTS PR00742 Glycosyl hydrolase family 35 signature 64 82 9.4E-54 T 28-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CU254_RS16490 0fc265ba88e513841fed0b8c65484bbb 609 ProSitePatterns PS01182 Glycosyl hydrolases family 35 putative active site. 176 188 - T 28-03-2018 IPR019801 Glycoside hydrolase, family 35, conserved site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CU254_RS16490 0fc265ba88e513841fed0b8c65484bbb 609 SUPERFAMILY SSF51445 34 357 4.15E-96 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS16490 0fc265ba88e513841fed0b8c65484bbb 609 Gene3D G3DSA:3.20.20.80 26 360 1.8E-78 T 28-03-2018 CU254_RS16490 0fc265ba88e513841fed0b8c65484bbb 609 PIRSF PIRSF006336 24 608 2.0E-201 T 28-03-2018 IPR026283 Beta-galactosidase 1-like GO:0004565 CU254_RS16490 0fc265ba88e513841fed0b8c65484bbb 609 Gene3D G3DSA:2.60.120.260 501 609 4.7E-21 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS16490 0fc265ba88e513841fed0b8c65484bbb 609 Pfam PF10518 TAT (twin-arginine translocation) pathway signal sequence 2 27 3.2E-5 T 28-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal CU254_RS16490 0fc265ba88e513841fed0b8c65484bbb 609 SUPERFAMILY SSF49785 470 599 1.04E-26 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS16490 0fc265ba88e513841fed0b8c65484bbb 609 Pfam PF01301 Glycosyl hydrolases family 35 40 354 4.6E-109 T 28-03-2018 IPR031330 Glycoside hydrolase 35, catalytic domain KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CU254_RS32005 57b8132089d820bd2a928820af984d02 418 Gene3D G3DSA:3.90.1150.10 299 418 8.1E-31 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS32005 57b8132089d820bd2a928820af984d02 418 PIRSF PIRSF000521 108 415 3.8E-43 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CU254_RS32005 57b8132089d820bd2a928820af984d02 418 PIRSF PIRSF000521 7 118 4.5E-9 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CU254_RS32005 57b8132089d820bd2a928820af984d02 418 SUPERFAMILY SSF53383 10 412 1.13E-130 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS32005 57b8132089d820bd2a928820af984d02 418 Pfam PF00202 Aminotransferase class-III 12 407 6.4E-118 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CU254_RS32005 57b8132089d820bd2a928820af984d02 418 Gene3D G3DSA:3.40.640.10 168 298 4.4E-40 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS32005 57b8132089d820bd2a928820af984d02 418 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 229 266 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CU254_RS32005 57b8132089d820bd2a928820af984d02 418 Gene3D G3DSA:3.90.1150.10 4 153 1.6E-44 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS20430 7f8542ecbbe93dc0010a2fced55c8eb1 336 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 44 325 5.3E-63 T 28-03-2018 IPR010067 Aliphatic sulfonates-binding protein GO:0016020|GO:0042626 CU254_RS20430 7f8542ecbbe93dc0010a2fced55c8eb1 336 Gene3D G3DSA:3.40.190.10 151 329 8.3E-32 T 28-03-2018 CU254_RS20430 7f8542ecbbe93dc0010a2fced55c8eb1 336 Gene3D G3DSA:3.40.190.10 29 150 6.5E-9 T 28-03-2018 CU254_RS20430 7f8542ecbbe93dc0010a2fced55c8eb1 336 SUPERFAMILY SSF53850 41 263 3.3E-43 T 28-03-2018 CU254_RS20430 7f8542ecbbe93dc0010a2fced55c8eb1 336 Pfam PF09084 NMT1/THI5 like 87 260 4.3E-11 T 28-03-2018 IPR015168 SsuA/THI5-like CU254_RS07005 84529e0d301cc100c2a85b455e7349f7 406 Pfam PF00005 ABC transporter 51 197 1.0E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS07005 84529e0d301cc100c2a85b455e7349f7 406 SMART SM00382 58 247 4.7E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS07005 84529e0d301cc100c2a85b455e7349f7 406 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 44 393 7.6E-113 T 28-03-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 CU254_RS07005 84529e0d301cc100c2a85b455e7349f7 406 Gene3D G3DSA:3.10.580.10 273 405 1.5E-15 T 28-03-2018 CU254_RS07005 84529e0d301cc100c2a85b455e7349f7 406 SUPERFAMILY SSF54631 279 392 1.77E-15 T 28-03-2018 CU254_RS07005 84529e0d301cc100c2a85b455e7349f7 406 Gene3D G3DSA:3.40.50.300 1 272 3.2E-70 T 28-03-2018 CU254_RS07005 84529e0d301cc100c2a85b455e7349f7 406 ProSitePatterns PS00211 ABC transporters family signature. 170 184 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS07005 84529e0d301cc100c2a85b455e7349f7 406 Pfam PF00571 CBS domain 282 330 8.9E-7 T 28-03-2018 IPR000644 CBS domain CU254_RS07005 84529e0d301cc100c2a85b455e7349f7 406 SUPERFAMILY SSF52540 48 275 1.24E-75 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS24820 7cabee5a799e74553c84f0e03b6ea465 252 Hamap MF_01408 Flavin-dependent thymidylate synthase [thyX]. 1 240 25.532 T 28-03-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 CU254_RS24820 7cabee5a799e74553c84f0e03b6ea465 252 Pfam PF02511 Thymidylate synthase complementing protein 33 224 1.5E-51 T 28-03-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 CU254_RS24820 7cabee5a799e74553c84f0e03b6ea465 252 TIGRFAM TIGR02170 thyX: thymidylate synthase, flavin-dependent 10 232 1.5E-58 T 28-03-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 CU254_RS24820 7cabee5a799e74553c84f0e03b6ea465 252 SUPERFAMILY SSF69796 34 237 7.72E-57 T 28-03-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 CU254_RS16450 22eaae08f8ddb9f0e1031dc11b453a09 573 Gene3D G3DSA:3.40.190.10 201 338 1.4E-25 T 28-03-2018 CU254_RS16450 22eaae08f8ddb9f0e1031dc11b453a09 573 Gene3D G3DSA:3.90.76.10 88 200 5.0E-26 T 28-03-2018 CU254_RS16450 22eaae08f8ddb9f0e1031dc11b453a09 573 SUPERFAMILY SSF53850 49 558 1.12E-77 T 28-03-2018 CU254_RS16450 22eaae08f8ddb9f0e1031dc11b453a09 573 Gene3D G3DSA:3.10.105.10 339 543 4.9E-28 T 28-03-2018 CU254_RS16450 22eaae08f8ddb9f0e1031dc11b453a09 573 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 101 469 3.3E-59 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CU254_RS16450 22eaae08f8ddb9f0e1031dc11b453a09 573 PIRSF PIRSF002741 7 566 4.2E-60 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CU254_RS33795 a4cecc8b54fe14062758448fb98fde87 199 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 6 176 5.8E-50 T 28-03-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 CU254_RS33795 a4cecc8b54fe14062758448fb98fde87 199 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 100 178 7.8E-18 T 28-03-2018 IPR020057 Ribosomal protein L25, beta domain CU254_RS33795 a4cecc8b54fe14062758448fb98fde87 199 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 11 91 3.0E-20 T 28-03-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 CU254_RS33795 a4cecc8b54fe14062758448fb98fde87 199 Pfam PF01386 Ribosomal L25p family 6 92 9.9E-25 T 28-03-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 CU254_RS33795 a4cecc8b54fe14062758448fb98fde87 199 SUPERFAMILY SSF50715 10 177 2.27E-48 T 28-03-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CU254_RS33795 a4cecc8b54fe14062758448fb98fde87 199 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 4 180 24.957 T 28-03-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 CU254_RS33795 a4cecc8b54fe14062758448fb98fde87 199 Gene3D G3DSA:2.40.240.10 3 94 8.1E-29 T 28-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CU254_RS33795 a4cecc8b54fe14062758448fb98fde87 199 Gene3D G3DSA:2.170.120.20 99 184 4.4E-20 T 28-03-2018 IPR020057 Ribosomal protein L25, beta domain CU254_RS08325 af1b0d300150c78efc9b89b6bef125c8 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 69 1.6E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS08325 af1b0d300150c78efc9b89b6bef125c8 201 Gene3D G3DSA:1.10.357.10 79 200 2.4E-13 T 28-03-2018 CU254_RS08325 af1b0d300150c78efc9b89b6bef125c8 201 Gene3D G3DSA:1.10.10.60 3 57 5.5E-19 T 28-03-2018 CU254_RS08325 af1b0d300150c78efc9b89b6bef125c8 201 SUPERFAMILY SSF46689 12 96 5.34E-20 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS08325 af1b0d300150c78efc9b89b6bef125c8 201 SUPERFAMILY SSF48498 91 194 1.31E-11 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS08325 af1b0d300150c78efc9b89b6bef125c8 201 Gene3D G3DSA:1.10.10.60 58 78 8.7E-13 T 28-03-2018 CU254_RS08325 af1b0d300150c78efc9b89b6bef125c8 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 1.8E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS08325 af1b0d300150c78efc9b89b6bef125c8 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 1.8E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS34610 e7f07c07231c4ffd2897907a9d1028ea 419 ProSitePatterns PS00217 Sugar transport proteins signature 2. 125 150 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CU254_RS34610 e7f07c07231c4ffd2897907a9d1028ea 419 Pfam PF07690 Major Facilitator Superfamily 34 378 1.0E-41 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS34610 e7f07c07231c4ffd2897907a9d1028ea 419 SUPERFAMILY SSF103473 20 416 2.09E-74 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS34610 e7f07c07231c4ffd2897907a9d1028ea 419 Gene3D G3DSA:1.20.1250.20 19 215 2.1E-32 T 28-03-2018 CU254_RS34610 e7f07c07231c4ffd2897907a9d1028ea 419 Gene3D G3DSA:1.20.1250.20 216 419 2.9E-25 T 28-03-2018 CU254_RS05280 ab8e192f7b7e801f3c1ace873234cd98 463 Gene3D G3DSA:1.20.1250.20 12 207 1.2E-35 T 28-03-2018 CU254_RS05280 ab8e192f7b7e801f3c1ace873234cd98 463 Gene3D G3DSA:1.20.1250.20 229 463 3.6E-38 T 28-03-2018 CU254_RS05280 ab8e192f7b7e801f3c1ace873234cd98 463 TIGRFAM TIGR00879 SP: MFS transporter, sugar porter (SP) family 13 449 8.6E-105 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CU254_RS05280 ab8e192f7b7e801f3c1ace873234cd98 463 ProSitePatterns PS00216 Sugar transport proteins signature 1. 307 323 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CU254_RS05280 ab8e192f7b7e801f3c1ace873234cd98 463 ProSitePatterns PS00217 Sugar transport proteins signature 2. 112 137 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CU254_RS05280 ab8e192f7b7e801f3c1ace873234cd98 463 Pfam PF00083 Sugar (and other) transporter 18 451 7.4E-108 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CU254_RS05280 ab8e192f7b7e801f3c1ace873234cd98 463 PRINTS PR00171 Sugar transporter signature 107 126 4.2E-26 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CU254_RS05280 ab8e192f7b7e801f3c1ace873234cd98 463 PRINTS PR00171 Sugar transporter signature 263 273 4.2E-26 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CU254_RS05280 ab8e192f7b7e801f3c1ace873234cd98 463 PRINTS PR00171 Sugar transporter signature 375 387 4.2E-26 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CU254_RS05280 ab8e192f7b7e801f3c1ace873234cd98 463 PRINTS PR00171 Sugar transporter signature 24 34 4.2E-26 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CU254_RS05280 ab8e192f7b7e801f3c1ace873234cd98 463 PRINTS PR00171 Sugar transporter signature 352 373 4.2E-26 T 28-03-2018 IPR003663 Sugar/inositol transporter GO:0016020|GO:0022891|GO:0055085 CU254_RS05280 ab8e192f7b7e801f3c1ace873234cd98 463 SUPERFAMILY SSF103473 9 450 4.58E-72 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS12875 e8bc281423b6cf14dd8ad6622aad3184 381 Gene3D G3DSA:1.20.140.10 220 381 6.2E-59 T 28-03-2018 CU254_RS12875 e8bc281423b6cf14dd8ad6622aad3184 381 SUPERFAMILY SSF47203 225 376 6.28E-55 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS12875 e8bc281423b6cf14dd8ad6622aad3184 381 PIRSF PIRSF016578 129 191 0.09 T 28-03-2018 CU254_RS12875 e8bc281423b6cf14dd8ad6622aad3184 381 PIRSF PIRSF016578 233 380 1.1E-13 T 28-03-2018 CU254_RS12875 e8bc281423b6cf14dd8ad6622aad3184 381 PIRSF PIRSF016578 23 80 7.2 T 28-03-2018 CU254_RS12875 e8bc281423b6cf14dd8ad6622aad3184 381 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 226 374 3.8E-51 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS12875 e8bc281423b6cf14dd8ad6622aad3184 381 Gene3D G3DSA:2.40.110.10 119 219 2.8E-33 T 28-03-2018 CU254_RS12875 e8bc281423b6cf14dd8ad6622aad3184 381 Gene3D G3DSA:1.10.540.10 1 113 9.3E-18 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS12875 e8bc281423b6cf14dd8ad6622aad3184 381 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 120 214 7.3E-23 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CU254_RS12875 e8bc281423b6cf14dd8ad6622aad3184 381 SUPERFAMILY SSF56645 2 239 2.09E-62 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS12875 e8bc281423b6cf14dd8ad6622aad3184 381 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 114 3.0E-14 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS00700 1a93067d79df3a4cd1ec0d6f72ef2419 223 Gene3D G3DSA:1.10.1660.10 1 100 4.9E-18 T 28-03-2018 CU254_RS00700 1a93067d79df3a4cd1ec0d6f72ef2419 223 SUPERFAMILY SSF46955 1 107 3.2E-15 T 28-03-2018 IPR009061 Putative DNA-binding domain CU254_RS00700 1a93067d79df3a4cd1ec0d6f72ef2419 223 Gene3D G3DSA:1.10.1660.10 128 222 1.9E-18 T 28-03-2018 CU254_RS00700 1a93067d79df3a4cd1ec0d6f72ef2419 223 SUPERFAMILY SSF46955 117 222 9.89E-16 T 28-03-2018 IPR009061 Putative DNA-binding domain CU254_RS00700 1a93067d79df3a4cd1ec0d6f72ef2419 223 Pfam PF13411 MerR HTH family regulatory protein 117 183 9.8E-13 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS00700 1a93067d79df3a4cd1ec0d6f72ef2419 223 Pfam PF00376 MerR family regulatory protein 3 39 6.1E-10 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS00700 1a93067d79df3a4cd1ec0d6f72ef2419 223 SMART SM00422 117 184 7.8E-5 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS00700 1a93067d79df3a4cd1ec0d6f72ef2419 223 SMART SM00422 1 69 1.1E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS00700 1a93067d79df3a4cd1ec0d6f72ef2419 223 ProSitePatterns PS00552 MerR-type HTH domain signature. 119 141 - T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS00700 1a93067d79df3a4cd1ec0d6f72ef2419 223 Gene3D G3DSA:1.10.10.10 101 127 0.38 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS38835 97cf720ba10b04ef8108fc73cd48108e 435 SUPERFAMILY SSF51556 58 352 1.33E-82 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS38835 97cf720ba10b04ef8108fc73cd48108e 435 Gene3D G3DSA:3.20.20.140 70 353 1.1E-57 T 28-03-2018 CU254_RS38835 97cf720ba10b04ef8108fc73cd48108e 435 SUPERFAMILY SSF51338 318 434 2.08E-19 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS38835 97cf720ba10b04ef8108fc73cd48108e 435 Pfam PF01979 Amidohydrolase family 55 408 2.8E-59 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CU254_RS38835 97cf720ba10b04ef8108fc73cd48108e 435 SUPERFAMILY SSF51338 18 77 1.3E-6 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS38835 97cf720ba10b04ef8108fc73cd48108e 435 Gene3D G3DSA:2.30.40.10 5 69 2.8E-7 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS07940 2673e4e447652dae9450e47eb9492ddc 597 Pfam PF00664 ABC transporter transmembrane region 42 310 1.7E-37 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CU254_RS07940 2673e4e447652dae9450e47eb9492ddc 597 SUPERFAMILY SSF90123 20 345 2.22E-62 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CU254_RS07940 2673e4e447652dae9450e47eb9492ddc 597 ProSitePatterns PS00211 ABC transporters family signature. 497 511 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS07940 2673e4e447652dae9450e47eb9492ddc 597 SMART SM00382 385 571 1.9E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS07940 2673e4e447652dae9450e47eb9492ddc 597 Gene3D G3DSA:1.20.1560.10 10 346 5.4E-55 T 28-03-2018 CU254_RS07940 2673e4e447652dae9450e47eb9492ddc 597 Gene3D G3DSA:3.40.50.300 351 597 6.5E-76 T 28-03-2018 CU254_RS07940 2673e4e447652dae9450e47eb9492ddc 597 SUPERFAMILY SSF52540 350 593 1.14E-88 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS07940 2673e4e447652dae9450e47eb9492ddc 597 Pfam PF00005 ABC transporter 376 525 8.2E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS13325 419c23a2317415a4e1a3769080ff95a1 475 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 179 194 - T 28-03-2018 IPR019826 Carboxylesterase type B, active site CU254_RS13325 419c23a2317415a4e1a3769080ff95a1 475 ProSitePatterns PS00941 Carboxylesterases type-B signature 2. 86 96 - T 28-03-2018 IPR019819 Carboxylesterase type B, conserved site CU254_RS13325 419c23a2317415a4e1a3769080ff95a1 475 Pfam PF00135 Carboxylesterase family 19 446 1.9E-99 T 28-03-2018 IPR002018 Carboxylesterase, type B CU254_RS13325 419c23a2317415a4e1a3769080ff95a1 475 Gene3D G3DSA:3.40.50.1820 8 460 1.0E-117 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS13325 419c23a2317415a4e1a3769080ff95a1 475 SUPERFAMILY SSF53474 19 442 2.18E-101 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS07535 db5e66134c872eca11d85e6fe8da0cf5 315 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 4 313 2.2E-28 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CU254_RS07535 db5e66134c872eca11d85e6fe8da0cf5 315 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 222 238 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CU254_RS07535 db5e66134c872eca11d85e6fe8da0cf5 315 SUPERFAMILY SSF51735 101 283 4.68E-60 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS07535 db5e66134c872eca11d85e6fe8da0cf5 315 Gene3D G3DSA:3.40.50.720 114 285 6.4E-59 T 28-03-2018 CU254_RS07535 db5e66134c872eca11d85e6fe8da0cf5 315 Gene3D G3DSA:3.40.50.720 1 113 2.5E-33 T 28-03-2018 CU254_RS07535 db5e66134c872eca11d85e6fe8da0cf5 315 SUPERFAMILY SSF52283 2 133 2.65E-31 T 28-03-2018 CU254_RS07535 db5e66134c872eca11d85e6fe8da0cf5 315 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 193 215 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CU254_RS07535 db5e66134c872eca11d85e6fe8da0cf5 315 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 109 282 9.9E-59 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CU254_RS09235 9dd9411c6a5747a36adb512bb91f583e 296 Pfam PF02779 Transketolase, pyrimidine binding domain 3 162 2.5E-21 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CU254_RS09235 9dd9411c6a5747a36adb512bb91f583e 296 Gene3D G3DSA:3.40.50.920 172 296 5.3E-15 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CU254_RS09235 9dd9411c6a5747a36adb512bb91f583e 296 SUPERFAMILY SSF52518 3 162 5.3E-32 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS09235 9dd9411c6a5747a36adb512bb91f583e 296 SUPERFAMILY SSF52922 175 293 9.16E-12 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CU254_RS09235 9dd9411c6a5747a36adb512bb91f583e 296 SMART SM00861 2 167 7.8E-18 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CU254_RS09235 9dd9411c6a5747a36adb512bb91f583e 296 Gene3D G3DSA:3.40.50.970 4 171 6.1E-28 T 28-03-2018 CU254_RS08660 8fd99e032f91f5a2cbbf4d5f09d0541e 1195 Pfam PF14579 Helix-hairpin-helix motif 841 927 4.7E-26 T 28-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CU254_RS08660 8fd99e032f91f5a2cbbf4d5f09d0541e 1195 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 6 1072 0.0 T 28-03-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CU254_RS08660 8fd99e032f91f5a2cbbf4d5f09d0541e 1195 Gene3D G3DSA:2.40.50.140 1013 1104 2.0E-12 T 28-03-2018 CU254_RS08660 8fd99e032f91f5a2cbbf4d5f09d0541e 1195 Gene3D G3DSA:1.10.150.280 820 926 1.4E-8 T 28-03-2018 CU254_RS08660 8fd99e032f91f5a2cbbf4d5f09d0541e 1195 Gene3D G3DSA:3.20.20.140 2 276 1.3E-47 T 28-03-2018 CU254_RS08660 8fd99e032f91f5a2cbbf4d5f09d0541e 1195 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 322 761 7.0E-162 T 28-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CU254_RS08660 8fd99e032f91f5a2cbbf4d5f09d0541e 1195 Pfam PF02811 PHP domain 8 200 7.0E-47 T 28-03-2018 IPR004013 PHP domain GO:0003824 CU254_RS08660 8fd99e032f91f5a2cbbf4d5f09d0541e 1195 SMART SM00481 7 74 1.4E-31 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CU254_RS08660 8fd99e032f91f5a2cbbf4d5f09d0541e 1195 SUPERFAMILY SSF89550 127 276 3.14E-29 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CU254_RS08660 8fd99e032f91f5a2cbbf4d5f09d0541e 1195 SUPERFAMILY SSF89550 6 91 3.14E-29 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CU254_RS12645 81bb0d224c7c76194ae13476fd05900b 605 Gene3D G3DSA:3.60.20.10 2 237 3.6E-63 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CU254_RS12645 81bb0d224c7c76194ae13476fd05900b 605 Pfam PF13522 Glutamine amidotransferase domain 63 191 1.7E-21 T 28-03-2018 CU254_RS12645 81bb0d224c7c76194ae13476fd05900b 605 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 605 35.986 T 28-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 CU254_RS12645 81bb0d224c7c76194ae13476fd05900b 605 Gene3D G3DSA:3.40.50.10490 238 455 4.1E-54 T 28-03-2018 CU254_RS12645 81bb0d224c7c76194ae13476fd05900b 605 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 605 1.2E-213 T 28-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 CU254_RS12645 81bb0d224c7c76194ae13476fd05900b 605 Gene3D G3DSA:3.40.50.10490 456 603 4.0E-43 T 28-03-2018 CU254_RS12645 81bb0d224c7c76194ae13476fd05900b 605 Pfam PF01380 SIS domain 290 415 1.1E-25 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CU254_RS12645 81bb0d224c7c76194ae13476fd05900b 605 Pfam PF01380 SIS domain 460 585 4.1E-19 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CU254_RS12645 81bb0d224c7c76194ae13476fd05900b 605 SUPERFAMILY SSF53697 243 605 1.3E-92 T 28-03-2018 CU254_RS12645 81bb0d224c7c76194ae13476fd05900b 605 SUPERFAMILY SSF56235 2 228 1.97E-64 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CU254_RS06185 de1c1b5e98e288c203e586ff1dcee2b6 788 Pfam PF09371 Tex-like protein N-terminal domain 10 194 4.0E-69 T 28-03-2018 IPR018974 Tex-like protein, N-terminal CU254_RS06185 de1c1b5e98e288c203e586ff1dcee2b6 788 SUPERFAMILY SSF158832 4 326 2.75E-118 T 28-03-2018 CU254_RS06185 de1c1b5e98e288c203e586ff1dcee2b6 788 Pfam PF00575 S1 RNA binding domain 655 726 7.4E-18 T 28-03-2018 IPR003029 S1 domain GO:0003676 CU254_RS06185 de1c1b5e98e288c203e586ff1dcee2b6 788 Gene3D G3DSA:2.40.50.140 649 730 2.6E-22 T 28-03-2018 CU254_RS06185 de1c1b5e98e288c203e586ff1dcee2b6 788 SMART SM00316 655 726 1.4E-24 T 28-03-2018 IPR022967 RNA-binding domain, S1 CU254_RS06185 de1c1b5e98e288c203e586ff1dcee2b6 788 Gene3D G3DSA:1.10.150.310 505 636 2.6E-43 T 28-03-2018 CU254_RS06185 de1c1b5e98e288c203e586ff1dcee2b6 788 SUPERFAMILY SSF47781 476 564 3.89E-26 T 28-03-2018 IPR010994 RuvA domain 2-like CU254_RS06185 de1c1b5e98e288c203e586ff1dcee2b6 788 SUPERFAMILY SSF47781 566 637 2.45E-19 T 28-03-2018 IPR010994 RuvA domain 2-like CU254_RS06185 de1c1b5e98e288c203e586ff1dcee2b6 788 Gene3D G3DSA:1.10.3500.10 360 504 4.0E-39 T 28-03-2018 IPR023323 Tex-like domain CU254_RS06185 de1c1b5e98e288c203e586ff1dcee2b6 788 Gene3D G3DSA:1.10.10.650 3 103 6.7E-34 T 28-03-2018 IPR023319 Tex-like protein, HTH domain CU254_RS06185 de1c1b5e98e288c203e586ff1dcee2b6 788 SUPERFAMILY SSF53098 327 475 2.65E-50 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS06185 de1c1b5e98e288c203e586ff1dcee2b6 788 Pfam PF12836 Helix-hairpin-helix motif 497 561 4.6E-28 T 28-03-2018 CU254_RS06185 de1c1b5e98e288c203e586ff1dcee2b6 788 SMART SM00732 331 430 1.2E-38 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 CU254_RS06185 de1c1b5e98e288c203e586ff1dcee2b6 788 SUPERFAMILY SSF50249 644 728 9.7E-23 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CU254_RS06185 de1c1b5e98e288c203e586ff1dcee2b6 788 Pfam PF16921 Tex protein YqgF-like domain 332 457 5.0E-52 T 28-03-2018 IPR032639 Tex protein, YqgF-like domain CU254_RS06185 de1c1b5e98e288c203e586ff1dcee2b6 788 Gene3D G3DSA:1.10.3500.10 104 359 2.9E-80 T 28-03-2018 IPR023323 Tex-like domain CU254_RS33435 cea943550816fbbd42b8ad0ec591cd42 182 Gene3D G3DSA:1.10.1740.10 1 99 6.5E-26 T 28-03-2018 CU254_RS33435 cea943550816fbbd42b8ad0ec591cd42 182 Gene3D G3DSA:1.10.10.10 100 181 2.3E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS33435 cea943550816fbbd42b8ad0ec591cd42 182 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 16 172 7.8E-27 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS33435 cea943550816fbbd42b8ad0ec591cd42 182 SUPERFAMILY SSF88946 3 98 1.78E-26 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS33435 cea943550816fbbd42b8ad0ec591cd42 182 Pfam PF08281 Sigma-70, region 4 119 170 8.4E-12 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS33435 cea943550816fbbd42b8ad0ec591cd42 182 SUPERFAMILY SSF88659 109 174 2.43E-13 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS33435 cea943550816fbbd42b8ad0ec591cd42 182 Pfam PF04542 Sigma-70 region 2 20 87 5.6E-18 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS17595 1ae542d22e4d22ad9dfbdc11192be419 555 Gene3D G3DSA:2.30.40.10 2 125 1.8E-18 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS17595 1ae542d22e4d22ad9dfbdc11192be419 555 Pfam PF07969 Amidohydrolase family 61 543 1.1E-112 T 28-03-2018 IPR013108 Amidohydrolase 3 CU254_RS17595 1ae542d22e4d22ad9dfbdc11192be419 555 Gene3D G3DSA:3.20.20.140 195 487 1.6E-58 T 28-03-2018 CU254_RS17595 1ae542d22e4d22ad9dfbdc11192be419 555 SUPERFAMILY SSF51556 207 504 3.74E-37 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS17595 1ae542d22e4d22ad9dfbdc11192be419 555 SUPERFAMILY SSF51556 71 131 3.74E-37 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS17595 1ae542d22e4d22ad9dfbdc11192be419 555 Gene3D G3DSA:2.30.40.10 488 551 6.3E-12 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS17595 1ae542d22e4d22ad9dfbdc11192be419 555 SUPERFAMILY SSF51338 8 72 9.88E-24 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS17595 1ae542d22e4d22ad9dfbdc11192be419 555 SUPERFAMILY SSF51338 503 546 9.88E-24 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS01245 f3d6a27a881756e21809a953364247c3 70 SUPERFAMILY SSF46955 8 60 1.79E-11 T 28-03-2018 IPR009061 Putative DNA-binding domain CU254_RS01245 f3d6a27a881756e21809a953364247c3 70 Gene3D G3DSA:1.10.1660.10 5 63 1.0E-12 T 28-03-2018 CU254_RS01245 f3d6a27a881756e21809a953364247c3 70 Pfam PF12728 Helix-turn-helix domain 9 58 2.7E-11 T 28-03-2018 CU254_RS01245 f3d6a27a881756e21809a953364247c3 70 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 9 57 3.2E-11 T 28-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 CU254_RS25300 6b132682a6330855f33bbbe8f3dc56a2 492 SUPERFAMILY SSF103473 271 486 3.14E-32 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS25300 6b132682a6330855f33bbbe8f3dc56a2 492 SUPERFAMILY SSF103473 11 209 3.14E-32 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS25300 6b132682a6330855f33bbbe8f3dc56a2 492 ProSitePatterns PS01022 PTR2 family proton/oligopeptide symporters signature 1. 80 104 - T 28-03-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 CU254_RS25300 6b132682a6330855f33bbbe8f3dc56a2 492 Gene3D G3DSA:1.20.1250.20 277 488 1.2E-14 T 28-03-2018 CU254_RS25300 6b132682a6330855f33bbbe8f3dc56a2 492 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 154 166 - T 28-03-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 CU254_RS25300 6b132682a6330855f33bbbe8f3dc56a2 492 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 12 488 5.9E-136 T 28-03-2018 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 CU254_RS25300 6b132682a6330855f33bbbe8f3dc56a2 492 Gene3D G3DSA:1.20.1250.20 8 207 2.6E-25 T 28-03-2018 CU254_RS25300 6b132682a6330855f33bbbe8f3dc56a2 492 Pfam PF00854 POT family 92 458 4.2E-75 T 28-03-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 CU254_RS15095 a177d9e8011025fa2373cba6ae3cf47d 165 Gene3D G3DSA:3.30.530.20 33 162 2.6E-29 T 28-03-2018 IPR023393 START-like domain CU254_RS15095 a177d9e8011025fa2373cba6ae3cf47d 165 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 44 152 1.8E-18 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CU254_RS15095 a177d9e8011025fa2373cba6ae3cf47d 165 SUPERFAMILY SSF55961 27 162 2.55E-32 T 28-03-2018 CU254_RS15840 7c59a410e13b2b495abf2f625dddd02f 186 Pfam PF13580 SIS domain 19 139 8.2E-28 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CU254_RS15840 7c59a410e13b2b495abf2f625dddd02f 186 SUPERFAMILY SSF53697 14 183 4.04E-47 T 28-03-2018 CU254_RS15840 7c59a410e13b2b495abf2f625dddd02f 186 Gene3D G3DSA:3.40.50.10490 1 186 4.4E-38 T 28-03-2018 CU254_RS39130 082a293d919f9a7dde627a10668f2e3c 481 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 186 245 1.3E-17 T 28-03-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 CU254_RS39130 082a293d919f9a7dde627a10668f2e3c 481 Pfam PF01743 Poly A polymerase head domain 35 158 8.3E-32 T 28-03-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 CU254_RS39130 082a293d919f9a7dde627a10668f2e3c 481 SUPERFAMILY SSF81301 17 154 1.55E-36 T 28-03-2018 CU254_RS39130 082a293d919f9a7dde627a10668f2e3c 481 TIGRFAM TIGR02692 tRNA_CCA_actino: CCA tRNA nucleotidyltransferase 8 472 9.6E-238 T 28-03-2018 IPR014065 tRNA adenylyltransferase CU254_RS39130 082a293d919f9a7dde627a10668f2e3c 481 SUPERFAMILY SSF81891 158 472 9.29E-65 T 28-03-2018 CU254_RS39130 082a293d919f9a7dde627a10668f2e3c 481 Gene3D G3DSA:3.30.460.10 14 158 1.0E-43 T 28-03-2018 CU254_RS39130 082a293d919f9a7dde627a10668f2e3c 481 Gene3D G3DSA:1.10.3090.10 159 472 2.8E-69 T 28-03-2018 CU254_RS39130 082a293d919f9a7dde627a10668f2e3c 481 Pfam PF01966 HD domain 261 387 5.4E-14 T 28-03-2018 IPR006674 HD domain CU254_RS39130 082a293d919f9a7dde627a10668f2e3c 481 TIGRFAM TIGR00277 HDIG: HDIG domain 258 343 6.6E-19 T 28-03-2018 IPR006675 HDIG domain CU254_RS39130 082a293d919f9a7dde627a10668f2e3c 481 SMART SM00471 257 417 2.1E-5 T 28-03-2018 IPR003607 HD/PDEase domain CU254_RS07785 85d7afa77f180fa910531ea3e9c96b46 398 SUPERFAMILY SSF51621 76 323 5.34E-17 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CU254_RS07785 85d7afa77f180fa910531ea3e9c96b46 398 Gene3D G3DSA:3.20.20.360 45 361 2.4E-42 T 28-03-2018 CU254_RS07785 85d7afa77f180fa910531ea3e9c96b46 398 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 167 278 6.1E-5 T 28-03-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 CU254_RS30795 7cb090c16cd6fee726e40e3dd6d020e3 253 SUPERFAMILY SSF100950 74 233 2.41E-30 T 28-03-2018 CU254_RS30795 7cb090c16cd6fee726e40e3dd6d020e3 253 SMART SM00420 6 58 1.5E-15 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CU254_RS30795 7cb090c16cd6fee726e40e3dd6d020e3 253 Pfam PF00455 DeoR C terminal sensor domain 75 232 5.3E-52 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain CU254_RS30795 7cb090c16cd6fee726e40e3dd6d020e3 253 SMART SM01134 73 234 1.6E-72 T 28-03-2018 CU254_RS30795 7cb090c16cd6fee726e40e3dd6d020e3 253 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 7.9E-8 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CU254_RS30795 7cb090c16cd6fee726e40e3dd6d020e3 253 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 7.9E-8 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CU254_RS30795 7cb090c16cd6fee726e40e3dd6d020e3 253 Gene3D G3DSA:3.40.50.1360 74 238 3.2E-41 T 28-03-2018 CU254_RS30795 7cb090c16cd6fee726e40e3dd6d020e3 253 Gene3D G3DSA:1.10.10.10 1 73 1.6E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS30795 7cb090c16cd6fee726e40e3dd6d020e3 253 SUPERFAMILY SSF46785 5 61 1.18E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS30795 7cb090c16cd6fee726e40e3dd6d020e3 253 Pfam PF08220 DeoR-like helix-turn-helix domain 6 60 2.6E-15 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CU254_RS26790 6f9ebc8c5d64c7c91ebc460214fed24e 264 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 102 122 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CU254_RS26790 6f9ebc8c5d64c7c91ebc460214fed24e 264 Pfam PF00378 Enoyl-CoA hydratase/isomerase 15 258 5.1E-71 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CU254_RS26790 6f9ebc8c5d64c7c91ebc460214fed24e 264 Gene3D G3DSA:3.90.226.10 1 218 4.7E-66 T 28-03-2018 CU254_RS26790 6f9ebc8c5d64c7c91ebc460214fed24e 264 Gene3D G3DSA:1.10.12.10 219 263 4.8E-11 T 28-03-2018 IPR014748 Crontonase, C-terminal CU254_RS26790 6f9ebc8c5d64c7c91ebc460214fed24e 264 SUPERFAMILY SSF52096 1 257 3.74E-80 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS26790 6f9ebc8c5d64c7c91ebc460214fed24e 264 Hamap MF_01934 1,4-dihydroxy-2-naphthoyl-CoA synthase [menB]. 1 263 47.449 T 28-03-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 CU254_RS38875 08ac20488601eaae86d7d23c581d97c8 362 SUPERFAMILY SSF51735 299 358 1.18E-94 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS38875 08ac20488601eaae86d7d23c581d97c8 362 SUPERFAMILY SSF51735 6 188 1.18E-94 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS38875 08ac20488601eaae86d7d23c581d97c8 362 SUPERFAMILY SSF55347 193 301 6.67E-35 T 28-03-2018 CU254_RS38875 08ac20488601eaae86d7d23c581d97c8 362 TIGRFAM TIGR03450 mycothiol_INO1: inositol 1-phosphate synthase 7 356 1.3E-211 T 28-03-2018 IPR017815 Myo-inositol 1-phosphate synthase, actinobacteria CU254_RS38875 08ac20488601eaae86d7d23c581d97c8 362 Gene3D G3DSA:3.40.50.720 296 357 9.0E-15 T 28-03-2018 CU254_RS38875 08ac20488601eaae86d7d23c581d97c8 362 Gene3D G3DSA:3.40.50.720 2 204 7.9E-59 T 28-03-2018 CU254_RS38875 08ac20488601eaae86d7d23c581d97c8 362 Gene3D G3DSA:3.30.360.10 205 295 1.2E-36 T 28-03-2018 CU254_RS38875 08ac20488601eaae86d7d23c581d97c8 362 Pfam PF01658 Myo-inositol-1-phosphate synthase 194 302 4.1E-32 T 28-03-2018 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 CU254_RS38875 08ac20488601eaae86d7d23c581d97c8 362 PIRSF PIRSF015578 2 357 3.6E-95 T 28-03-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 CU254_RS12190 e4d8156b19df07462294adf28c2bced0 312 Gene3D G3DSA:3.40.50.80 98 211 1.0E-14 T 28-03-2018 CU254_RS12190 e4d8156b19df07462294adf28c2bced0 312 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 233 302 2.5E-12 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CU254_RS12190 e4d8156b19df07462294adf28c2bced0 312 SUPERFAMILY SSF54292 207 310 4.06E-26 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CU254_RS12190 e4d8156b19df07462294adf28c2bced0 312 SUPERFAMILY SSF63380 5 97 4.66E-25 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CU254_RS12190 e4d8156b19df07462294adf28c2bced0 312 Gene3D G3DSA:2.40.30.10 2 97 1.0E-15 T 28-03-2018 CU254_RS12190 e4d8156b19df07462294adf28c2bced0 312 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 261 269 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CU254_RS12190 e4d8156b19df07462294adf28c2bced0 312 Gene3D G3DSA:3.10.20.30 212 312 9.7E-22 T 28-03-2018 IPR012675 Beta-grasp domain CU254_RS12190 e4d8156b19df07462294adf28c2bced0 312 PRINTS PR00409 Phthalate dioxygenase reductase family signature 108 127 2.1E-34 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CU254_RS12190 e4d8156b19df07462294adf28c2bced0 312 PRINTS PR00409 Phthalate dioxygenase reductase family signature 49 63 2.1E-34 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CU254_RS12190 e4d8156b19df07462294adf28c2bced0 312 PRINTS PR00409 Phthalate dioxygenase reductase family signature 27 37 2.1E-34 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CU254_RS12190 e4d8156b19df07462294adf28c2bced0 312 PRINTS PR00409 Phthalate dioxygenase reductase family signature 73 87 2.1E-34 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CU254_RS12190 e4d8156b19df07462294adf28c2bced0 312 PRINTS PR00409 Phthalate dioxygenase reductase family signature 37 49 2.1E-34 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CU254_RS12190 e4d8156b19df07462294adf28c2bced0 312 PRINTS PR00409 Phthalate dioxygenase reductase family signature 133 142 2.1E-34 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CU254_RS12190 e4d8156b19df07462294adf28c2bced0 312 PRINTS PR00409 Phthalate dioxygenase reductase family signature 185 193 2.1E-34 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CU254_RS12190 e4d8156b19df07462294adf28c2bced0 312 SUPERFAMILY SSF52343 95 216 7.07E-23 T 28-03-2018 CU254_RS00215 dddaba0d78b695aa0952bf7039917f95 401 SUPERFAMILY SSF88659 97 155 3.14E-10 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS00215 dddaba0d78b695aa0952bf7039917f95 401 Gene3D G3DSA:1.25.40.120 200 393 0.11 T 28-03-2018 CU254_RS00215 dddaba0d78b695aa0952bf7039917f95 401 SUPERFAMILY SSF88946 6 92 5.89E-11 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS00215 dddaba0d78b695aa0952bf7039917f95 401 Pfam PF08281 Sigma-70, region 4 102 152 8.3E-11 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS00215 dddaba0d78b695aa0952bf7039917f95 401 Pfam PF04542 Sigma-70 region 2 9 75 4.9E-9 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS00215 dddaba0d78b695aa0952bf7039917f95 401 Gene3D G3DSA:1.10.10.10 106 199 5.7E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS00215 dddaba0d78b695aa0952bf7039917f95 401 Gene3D G3DSA:1.10.1740.10 2 80 7.4E-14 T 28-03-2018 CU254_RS00885 6e50371ab4794d4ffdb0741593293194 379 Gene3D G3DSA:3.40.50.150 10 270 1.3E-30 T 28-03-2018 CU254_RS00885 6e50371ab4794d4ffdb0741593293194 379 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 95 213 2.6E-19 T 28-03-2018 CU254_RS00885 6e50371ab4794d4ffdb0741593293194 379 SUPERFAMILY SSF53335 4 39 5.71E-24 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS00885 6e50371ab4794d4ffdb0741593293194 379 SUPERFAMILY SSF53335 72 211 5.71E-24 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS40225 787a1c4c0d14f74d1f347398cad8ebc2 205 Gene3D G3DSA:2.160.10.10 15 195 5.0E-33 T 28-03-2018 CU254_RS40225 787a1c4c0d14f74d1f347398cad8ebc2 205 SUPERFAMILY SSF51161 32 172 1.3E-35 T 28-03-2018 IPR011004 Trimeric LpxA-like CU254_RS40225 787a1c4c0d14f74d1f347398cad8ebc2 205 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 113 147 3.9E-9 T 28-03-2018 IPR001451 Hexapeptide repeat CU254_RS35655 c3884fc0eb4eefc1c5c1275a8cade648 376 Gene3D G3DSA:3.20.20.140 1 375 4.5E-141 T 28-03-2018 CU254_RS35655 c3884fc0eb4eefc1c5c1275a8cade648 376 SUPERFAMILY SSF51556 5 255 5.15E-105 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS35655 c3884fc0eb4eefc1c5c1275a8cade648 376 SUPERFAMILY SSF51556 293 372 5.15E-105 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS35655 c3884fc0eb4eefc1c5c1275a8cade648 376 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 11 371 1.5E-113 T 28-03-2018 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 CU254_RS08190 f4099ac4f5861a86711f7ac9add2560d 725 Gene3D G3DSA:2.40.40.20 565 722 8.9E-33 T 28-03-2018 CU254_RS08190 f4099ac4f5861a86711f7ac9add2560d 725 Gene3D G3DSA:3.40.228.10 380 552 3.6E-9 T 28-03-2018 CU254_RS08190 f4099ac4f5861a86711f7ac9add2560d 725 Pfam PF01568 Molydopterin dinucleotide binding domain 594 713 8.0E-22 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CU254_RS08190 f4099ac4f5861a86711f7ac9add2560d 725 Gene3D G3DSA:3.40.50.740 58 152 5.0E-18 T 28-03-2018 CU254_RS08190 f4099ac4f5861a86711f7ac9add2560d 725 Gene3D G3DSA:2.20.25.90 1 57 1.9E-14 T 28-03-2018 CU254_RS08190 f4099ac4f5861a86711f7ac9add2560d 725 SUPERFAMILY SSF50692 556 722 2.49E-34 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain CU254_RS08190 f4099ac4f5861a86711f7ac9add2560d 725 SMART SM00926 2 55 7.6E-12 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS08190 f4099ac4f5861a86711f7ac9add2560d 725 SUPERFAMILY SSF53706 4 574 6.81E-152 T 28-03-2018 CU254_RS08190 f4099ac4f5861a86711f7ac9add2560d 725 Pfam PF00384 Molybdopterin oxidoreductase 58 495 4.1E-54 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS08190 f4099ac4f5861a86711f7ac9add2560d 725 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 4 54 7.1E-8 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS08190 f4099ac4f5861a86711f7ac9add2560d 725 Gene3D G3DSA:3.40.228.10 153 362 1.1E-67 T 28-03-2018 CU254_RS21740 1b8e1c0b270ea3ddec5891c4dafd5fac 509 Gene3D G3DSA:3.40.47.10 321 482 4.0E-42 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS21740 1b8e1c0b270ea3ddec5891c4dafd5fac 509 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 223 239 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CU254_RS21740 1b8e1c0b270ea3ddec5891c4dafd5fac 509 SUPERFAMILY SSF53901 206 428 1.22E-70 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS21740 1b8e1c0b270ea3ddec5891c4dafd5fac 509 SUPERFAMILY SSF53901 53 178 1.22E-70 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS21740 1b8e1c0b270ea3ddec5891c4dafd5fac 509 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 434 489 9.5E-9 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS21740 1b8e1c0b270ea3ddec5891c4dafd5fac 509 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 56 310 2.4E-68 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CU254_RS21740 1b8e1c0b270ea3ddec5891c4dafd5fac 509 SMART SM00825 Beta-ketoacyl synthase 58 484 1.6E-106 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CU254_RS21740 1b8e1c0b270ea3ddec5891c4dafd5fac 509 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 314 430 1.3E-27 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CU254_RS21740 1b8e1c0b270ea3ddec5891c4dafd5fac 509 Gene3D G3DSA:3.40.47.10 48 320 5.2E-70 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS31415 5eaa6739109579032c0e40d31f48403e 383 SUPERFAMILY SSF53098 137 295 5.44E-28 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS31415 5eaa6739109579032c0e40d31f48403e 383 Pfam PF00665 Integrase core domain 137 254 8.0E-18 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CU254_RS31415 5eaa6739109579032c0e40d31f48403e 383 Pfam PF13011 leucine-zipper of insertion element IS481 19 76 8.5E-13 T 28-03-2018 IPR024967 DNA-binding domain, IS481-type CU254_RS31415 5eaa6739109579032c0e40d31f48403e 383 SUPERFAMILY SSF46689 12 116 2.87E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS31415 5eaa6739109579032c0e40d31f48403e 383 Gene3D G3DSA:3.30.420.10 126 357 4.6E-37 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS31415 5eaa6739109579032c0e40d31f48403e 383 Gene3D G3DSA:1.10.10.10 1 62 1.3E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS10375 5eaa6739109579032c0e40d31f48403e 383 SUPERFAMILY SSF53098 137 295 5.44E-28 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS10375 5eaa6739109579032c0e40d31f48403e 383 Pfam PF00665 Integrase core domain 137 254 8.0E-18 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CU254_RS10375 5eaa6739109579032c0e40d31f48403e 383 Pfam PF13011 leucine-zipper of insertion element IS481 19 76 8.5E-13 T 28-03-2018 IPR024967 DNA-binding domain, IS481-type CU254_RS10375 5eaa6739109579032c0e40d31f48403e 383 SUPERFAMILY SSF46689 12 116 2.87E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS10375 5eaa6739109579032c0e40d31f48403e 383 Gene3D G3DSA:3.30.420.10 126 357 4.6E-37 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS10375 5eaa6739109579032c0e40d31f48403e 383 Gene3D G3DSA:1.10.10.10 1 62 1.3E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS24415 5eaa6739109579032c0e40d31f48403e 383 SUPERFAMILY SSF53098 137 295 5.44E-28 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS24415 5eaa6739109579032c0e40d31f48403e 383 Pfam PF00665 Integrase core domain 137 254 8.0E-18 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CU254_RS24415 5eaa6739109579032c0e40d31f48403e 383 Pfam PF13011 leucine-zipper of insertion element IS481 19 76 8.5E-13 T 28-03-2018 IPR024967 DNA-binding domain, IS481-type CU254_RS24415 5eaa6739109579032c0e40d31f48403e 383 SUPERFAMILY SSF46689 12 116 2.87E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS24415 5eaa6739109579032c0e40d31f48403e 383 Gene3D G3DSA:3.30.420.10 126 357 4.6E-37 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS24415 5eaa6739109579032c0e40d31f48403e 383 Gene3D G3DSA:1.10.10.10 1 62 1.3E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS13265 5eaa6739109579032c0e40d31f48403e 383 SUPERFAMILY SSF53098 137 295 5.44E-28 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS13265 5eaa6739109579032c0e40d31f48403e 383 Pfam PF00665 Integrase core domain 137 254 8.0E-18 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CU254_RS13265 5eaa6739109579032c0e40d31f48403e 383 Pfam PF13011 leucine-zipper of insertion element IS481 19 76 8.5E-13 T 28-03-2018 IPR024967 DNA-binding domain, IS481-type CU254_RS13265 5eaa6739109579032c0e40d31f48403e 383 SUPERFAMILY SSF46689 12 116 2.87E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS13265 5eaa6739109579032c0e40d31f48403e 383 Gene3D G3DSA:3.30.420.10 126 357 4.6E-37 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS13265 5eaa6739109579032c0e40d31f48403e 383 Gene3D G3DSA:1.10.10.10 1 62 1.3E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS14390 acd3b4fb45fdaeb5a32f44302eb51d50 189 Gene3D G3DSA:1.10.10.10 130 188 2.2E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS14390 acd3b4fb45fdaeb5a32f44302eb51d50 189 SUPERFAMILY SSF88659 123 180 1.16E-14 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS14390 acd3b4fb45fdaeb5a32f44302eb51d50 189 SUPERFAMILY SSF88946 8 106 5.89E-21 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS14390 acd3b4fb45fdaeb5a32f44302eb51d50 189 Pfam PF04542 Sigma-70 region 2 32 95 9.4E-13 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS14390 acd3b4fb45fdaeb5a32f44302eb51d50 189 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 26 180 3.9E-24 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS14390 acd3b4fb45fdaeb5a32f44302eb51d50 189 Gene3D G3DSA:1.10.1740.10 3 124 1.1E-20 T 28-03-2018 CU254_RS14390 acd3b4fb45fdaeb5a32f44302eb51d50 189 Pfam PF08281 Sigma-70, region 4 127 177 1.6E-16 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS14390 acd3b4fb45fdaeb5a32f44302eb51d50 189 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 51 82 - T 28-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS03120 31a7d562fd8e11cb67c3934f4751eda5 609 Gene3D G3DSA:3.40.1000.10 456 609 1.0E-6 T 28-03-2018 CU254_RS03120 31a7d562fd8e11cb67c3934f4751eda5 609 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 44 67 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 CU254_RS03120 31a7d562fd8e11cb67c3934f4751eda5 609 Gene3D G3DSA:1.10.510.10 109 310 1.9E-49 T 28-03-2018 CU254_RS03120 31a7d562fd8e11cb67c3934f4751eda5 609 SMART SM00220 38 293 2.6E-61 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CU254_RS03120 31a7d562fd8e11cb67c3934f4751eda5 609 Pfam PF00069 Protein kinase domain 39 290 3.7E-47 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CU254_RS03120 31a7d562fd8e11cb67c3934f4751eda5 609 SUPERFAMILY SSF56112 29 295 5.26E-70 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS03120 31a7d562fd8e11cb67c3934f4751eda5 609 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 161 173 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CU254_RS03120 31a7d562fd8e11cb67c3934f4751eda5 609 Gene3D G3DSA:3.30.200.20 4 108 5.0E-19 T 28-03-2018 CU254_RS00545 23002a0a7c197937f82704a2d24532fd 426 SUPERFAMILY SSF56796 14 422 4.58E-98 T 28-03-2018 CU254_RS00545 23002a0a7c197937f82704a2d24532fd 426 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 184 212 - T 28-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 CU254_RS00545 23002a0a7c197937f82704a2d24532fd 426 Pfam PF00465 Iron-containing alcohol dehydrogenase 17 415 3.4E-103 T 28-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 CU254_RS00545 23002a0a7c197937f82704a2d24532fd 426 Gene3D G3DSA:1.20.1090.10 195 426 2.6E-54 T 28-03-2018 CU254_RS00545 23002a0a7c197937f82704a2d24532fd 426 Gene3D G3DSA:3.40.50.1970 16 193 5.8E-43 T 28-03-2018 CU254_RS32455 ecc31dacc830f9eab173ce4675860f56 576 SUPERFAMILY SSF47384 286 369 2.55E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS32455 ecc31dacc830f9eab173ce4675860f56 576 Pfam PF00672 HAMP domain 242 290 7.3E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS32455 ecc31dacc830f9eab173ce4675860f56 576 SMART SM00387 415 526 4.5E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS32455 ecc31dacc830f9eab173ce4675860f56 576 Gene3D G3DSA:1.10.287.130 285 365 5.3E-12 T 28-03-2018 CU254_RS32455 ecc31dacc830f9eab173ce4675860f56 576 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 416 525 1.5E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS32455 ecc31dacc830f9eab173ce4675860f56 576 Gene3D G3DSA:3.30.565.10 374 528 4.7E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS32455 ecc31dacc830f9eab173ce4675860f56 576 PRINTS PR00344 Bacterial sensor protein C-terminal signature 510 523 1.4E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS32455 ecc31dacc830f9eab173ce4675860f56 576 PRINTS PR00344 Bacterial sensor protein C-terminal signature 486 504 1.4E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS32455 ecc31dacc830f9eab173ce4675860f56 576 PRINTS PR00344 Bacterial sensor protein C-terminal signature 469 479 1.4E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS32455 ecc31dacc830f9eab173ce4675860f56 576 PRINTS PR00344 Bacterial sensor protein C-terminal signature 451 465 1.4E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS32455 ecc31dacc830f9eab173ce4675860f56 576 SUPERFAMILY SSF158472 242 292 2.09E-8 T 28-03-2018 CU254_RS32455 ecc31dacc830f9eab173ce4675860f56 576 SMART SM00388 302 369 3.7E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS32455 ecc31dacc830f9eab173ce4675860f56 576 Pfam PF00512 His Kinase A (phospho-acceptor) domain 303 369 3.0E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS32455 ecc31dacc830f9eab173ce4675860f56 576 SMART SM00304 242 294 1.6E-13 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS32455 ecc31dacc830f9eab173ce4675860f56 576 SUPERFAMILY SSF55874 359 524 1.02E-39 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS19535 de12c06d51231345a311492ce2824b54 1435 Gene3D G3DSA:2.60.120.260 1168 1309 3.0E-12 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS19535 de12c06d51231345a311492ce2824b54 1435 Gene3D G3DSA:2.60.120.260 81 224 7.1E-23 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS19535 de12c06d51231345a311492ce2824b54 1435 SUPERFAMILY SSF49785 1212 1293 2.89E-5 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS19535 de12c06d51231345a311492ce2824b54 1435 Pfam PF07971 Glycosyl hydrolase family 92 610 1139 8.2E-156 T 28-03-2018 IPR012939 Glycosyl hydrolase family 92 CU254_RS19535 de12c06d51231345a311492ce2824b54 1435 SUPERFAMILY SSF48208 633 686 6.97E-20 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CU254_RS19535 de12c06d51231345a311492ce2824b54 1435 SUPERFAMILY SSF48208 714 1121 6.97E-20 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CU254_RS19535 de12c06d51231345a311492ce2824b54 1435 Gene3D G3DSA:3.30.2080.10 986 1151 2.5E-64 T 28-03-2018 CU254_RS19535 de12c06d51231345a311492ce2824b54 1435 Gene3D G3DSA:2.70.98.10 396 695 9.8E-81 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 CU254_RS19535 de12c06d51231345a311492ce2824b54 1435 Pfam PF00754 F5/8 type C domain 88 211 1.0E-11 T 28-03-2018 IPR000421 Coagulation factor 5/8 C-terminal domain CU254_RS19535 de12c06d51231345a311492ce2824b54 1435 Gene3D G3DSA:1.20.1050.60 735 829 6.8E-30 T 28-03-2018 CU254_RS19535 de12c06d51231345a311492ce2824b54 1435 TIGRFAM TIGR01180 aman2_put: putative alpha-1,2-mannosidase 412 1141 3.4E-142 T 28-03-2018 IPR005887 Alpha-1,2-mannosidase, putative CU254_RS19535 de12c06d51231345a311492ce2824b54 1435 SUPERFAMILY SSF49785 89 207 6.72E-13 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS09920 45b94300892689063f78757fa943a5e3 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 247 7.3E-61 T 28-03-2018 CU254_RS09920 45b94300892689063f78757fa943a5e3 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS09920 45b94300892689063f78757fa943a5e3 254 SUPERFAMILY SSF51735 5 248 9.87E-76 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS09920 45b94300892689063f78757fa943a5e3 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 2.9E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS09920 45b94300892689063f78757fa943a5e3 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 2.9E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS09920 45b94300892689063f78757fa943a5e3 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 2.9E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS09920 45b94300892689063f78757fa943a5e3 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 4.4E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS09920 45b94300892689063f78757fa943a5e3 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 4.4E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS09920 45b94300892689063f78757fa943a5e3 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 4.4E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS09920 45b94300892689063f78757fa943a5e3 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 4.4E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS09920 45b94300892689063f78757fa943a5e3 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 4.4E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS09920 45b94300892689063f78757fa943a5e3 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 4.4E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS09920 45b94300892689063f78757fa943a5e3 254 Gene3D G3DSA:3.40.50.720 1 45 1.8E-9 T 28-03-2018 CU254_RS09920 45b94300892689063f78757fa943a5e3 254 Gene3D G3DSA:3.40.50.720 46 253 4.0E-58 T 28-03-2018 CU254_RS18485 b9451f237e3113a9066e092536ca4b11 325 SUPERFAMILY SSF53335 96 321 8.76E-16 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS18485 b9451f237e3113a9066e092536ca4b11 325 SUPERFAMILY SSF46785 7 78 5.38E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS18485 b9451f237e3113a9066e092536ca4b11 325 Pfam PF00891 O-methyltransferase 125 308 1.2E-7 T 28-03-2018 IPR001077 O-methyltransferase, family 2 GO:0008171 CU254_RS18485 b9451f237e3113a9066e092536ca4b11 325 Pfam PF16864 Dimerisation domain 9 88 2.5E-11 T 28-03-2018 IPR031725 Acetylserotonin O-methyltransferase, dimerisation domain CU254_RS18485 b9451f237e3113a9066e092536ca4b11 325 Gene3D G3DSA:3.40.50.150 76 325 3.9E-16 T 28-03-2018 CU254_RS18485 b9451f237e3113a9066e092536ca4b11 325 Gene3D G3DSA:1.10.10.10 1 75 1.8E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS18615 74cefa26c5c9bdc1dba5a0549c63fcc2 403 Pfam PF01494 FAD binding domain 1 335 1.2E-17 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CU254_RS18615 74cefa26c5c9bdc1dba5a0549c63fcc2 403 Gene3D G3DSA:3.50.50.60 1 371 3.9E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS18615 74cefa26c5c9bdc1dba5a0549c63fcc2 403 SUPERFAMILY SSF51905 1 165 9.99E-59 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS18615 74cefa26c5c9bdc1dba5a0549c63fcc2 403 SUPERFAMILY SSF51905 262 350 9.99E-59 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS18615 74cefa26c5c9bdc1dba5a0549c63fcc2 403 SUPERFAMILY SSF54373 170 240 7.85E-6 T 28-03-2018 CU254_RS31325 c4095b07ed1031677a38192d0b54cc51 288 Gene3D G3DSA:1.10.8.10 2 77 2.0E-15 T 28-03-2018 CU254_RS31325 c4095b07ed1031677a38192d0b54cc51 288 Pfam PF05175 Methyltransferase small domain 109 198 1.3E-11 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 CU254_RS31325 c4095b07ed1031677a38192d0b54cc51 288 SUPERFAMILY SSF53335 12 284 1.35E-43 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS31325 c4095b07ed1031677a38192d0b54cc51 288 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 191 197 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CU254_RS31325 c4095b07ed1031677a38192d0b54cc51 288 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 51 285 1.4E-40 T 28-03-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 CU254_RS31325 c4095b07ed1031677a38192d0b54cc51 288 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 28 282 2.1E-65 T 28-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 CU254_RS31325 c4095b07ed1031677a38192d0b54cc51 288 Gene3D G3DSA:3.40.50.150 79 288 2.1E-40 T 28-03-2018 CU254_RS31325 c4095b07ed1031677a38192d0b54cc51 288 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 6 286 39.798 T 28-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 CU254_RS29825 2699d509738a07b63d69d4820926a2ac 384 Pfam PF13421 SPFH domain-Band 7 family 26 236 2.6E-97 T 28-03-2018 IPR033880 SPFH domain, YdjI-like CU254_RS29825 2699d509738a07b63d69d4820926a2ac 384 SUPERFAMILY SSF117892 124 233 7.72E-10 T 28-03-2018 IPR001107 Band 7 domain CU254_RS29825 2699d509738a07b63d69d4820926a2ac 384 Pfam PF14237 Domain of unknown function (DUF4339) 321 364 2.4E-16 T 28-03-2018 IPR025640 Domain of unknown function DUF4339 Reactome: R-HSA-6798695 CU254_RS29825 2699d509738a07b63d69d4820926a2ac 384 Gene3D G3DSA:3.30.1490.40 301 374 4.0E-4 T 28-03-2018 IPR035445 GYF-like domain CU254_RS39575 0245a4556e8636e81e8ddd8c3977e4df 1071 SUPERFAMILY SSF56235 119 323 3.09E-99 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CU254_RS39575 0245a4556e8636e81e8ddd8c3977e4df 1071 SUPERFAMILY SSF56235 391 858 3.09E-99 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CU254_RS39575 0245a4556e8636e81e8ddd8c3977e4df 1071 Gene3D G3DSA:1.10.439.10 108 288 2.5E-37 T 28-03-2018 IPR023343 Penicillin amidase type, domain1 GO:0016811 CU254_RS39575 0245a4556e8636e81e8ddd8c3977e4df 1071 Pfam PF01804 Penicillin amidase 120 924 1.3E-122 T 28-03-2018 IPR002692 Penicillin/GL-7-ACA/AHL/aculeacin-A acylase GO:0016787|GO:0017000 CU254_RS39575 0245a4556e8636e81e8ddd8c3977e4df 1071 SMART SM00231 941 1071 0.0049 T 28-03-2018 IPR000421 Coagulation factor 5/8 C-terminal domain CU254_RS39575 0245a4556e8636e81e8ddd8c3977e4df 1071 Pfam PF00754 F5/8 type C domain 950 1065 2.2E-23 T 28-03-2018 IPR000421 Coagulation factor 5/8 C-terminal domain CU254_RS39575 0245a4556e8636e81e8ddd8c3977e4df 1071 SUPERFAMILY SSF49785 937 1069 9.92E-29 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS39575 0245a4556e8636e81e8ddd8c3977e4df 1071 Gene3D G3DSA:2.60.120.260 934 1071 2.4E-36 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS39575 0245a4556e8636e81e8ddd8c3977e4df 1071 Gene3D G3DSA:1.10.287.150 289 331 4.9E-19 T 28-03-2018 CU254_RS39575 0245a4556e8636e81e8ddd8c3977e4df 1071 Gene3D G3DSA:3.60.20.10 399 481 3.1E-16 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CU254_RS39575 0245a4556e8636e81e8ddd8c3977e4df 1071 Gene3D G3DSA:3.60.20.10 484 776 5.4E-38 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CU254_RS20410 1d5fd7d8e5f88afff10ac453cac9d55e 316 Gene3D G3DSA:3.30.450.80 5 152 3.7E-11 T 28-03-2018 CU254_RS20410 1d5fd7d8e5f88afff10ac453cac9d55e 316 Pfam PF03472 Autoinducer binding domain 29 152 1.7E-7 T 28-03-2018 IPR005143 Transcription factor LuxR-like, autoinducer-binding domain CU254_RS20410 1d5fd7d8e5f88afff10ac453cac9d55e 316 Pfam PF00196 Bacterial regulatory proteins, luxR family 245 300 1.2E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS20410 1d5fd7d8e5f88afff10ac453cac9d55e 316 SMART SM00421 243 300 1.2E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS20410 1d5fd7d8e5f88afff10ac453cac9d55e 316 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 260 276 5.1E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS20410 1d5fd7d8e5f88afff10ac453cac9d55e 316 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 276 288 5.1E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS20410 1d5fd7d8e5f88afff10ac453cac9d55e 316 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 246 260 5.1E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS20410 1d5fd7d8e5f88afff10ac453cac9d55e 316 ProSitePatterns PS00622 LuxR-type HTH domain signature. 260 287 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS20410 1d5fd7d8e5f88afff10ac453cac9d55e 316 Gene3D G3DSA:1.10.10.10 153 308 1.3E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS20410 1d5fd7d8e5f88afff10ac453cac9d55e 316 SUPERFAMILY SSF46894 239 305 1.29E-15 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS20410 1d5fd7d8e5f88afff10ac453cac9d55e 316 SUPERFAMILY SSF55781 29 155 2.94E-9 T 28-03-2018 IPR029016 GAF domain-like CU254_RS22585 cdbe94be4e09a4d79cab30922a4ba433 222 Gene3D G3DSA:1.10.10.10 131 222 1.7E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS22585 cdbe94be4e09a4d79cab30922a4ba433 222 Pfam PF00072 Response regulator receiver domain 4 115 1.1E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS22585 cdbe94be4e09a4d79cab30922a4ba433 222 PIRSF PIRSF006171 1 222 2.4E-70 T 28-03-2018 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0001071|GO:0003677|GO:0005737|GO:0009605 CU254_RS22585 cdbe94be4e09a4d79cab30922a4ba433 222 SUPERFAMILY SSF46785 145 221 2.32E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS22585 cdbe94be4e09a4d79cab30922a4ba433 222 SMART SM00448 2 115 1.5E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS22585 cdbe94be4e09a4d79cab30922a4ba433 222 Gene3D G3DSA:3.40.50.2300 1 130 1.7E-28 T 28-03-2018 CU254_RS22585 cdbe94be4e09a4d79cab30922a4ba433 222 SUPERFAMILY SSF52172 2 151 2.13E-32 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS29365 85b3a8b107c013e3c126042818ba859e 264 SUPERFAMILY SSF51735 19 261 1.42E-76 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS29365 85b3a8b107c013e3c126042818ba859e 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 170 189 5.3E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS29365 85b3a8b107c013e3c126042818ba859e 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 96 107 5.3E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS29365 85b3a8b107c013e3c126042818ba859e 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 157 5.3E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS29365 85b3a8b107c013e3c126042818ba859e 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 22 39 2.8E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS29365 85b3a8b107c013e3c126042818ba859e 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 189 2.8E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS29365 85b3a8b107c013e3c126042818ba859e 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 191 208 2.8E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS29365 85b3a8b107c013e3c126042818ba859e 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 96 107 2.8E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS29365 85b3a8b107c013e3c126042818ba859e 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 159 2.8E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS29365 85b3a8b107c013e3c126042818ba859e 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 225 245 2.8E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS29365 85b3a8b107c013e3c126042818ba859e 264 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 21 201 0.0014 T 28-03-2018 CU254_RS29365 85b3a8b107c013e3c126042818ba859e 264 Gene3D G3DSA:3.40.50.720 62 264 1.7E-63 T 28-03-2018 CU254_RS29365 85b3a8b107c013e3c126042818ba859e 264 Gene3D G3DSA:3.40.50.720 13 61 7.3E-8 T 28-03-2018 CU254_RS29365 85b3a8b107c013e3c126042818ba859e 264 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 27 260 2.0E-63 T 28-03-2018 CU254_RS22075 ffdc8ca59f63fce42dcca62a679ac9d6 266 Gene3D G3DSA:3.40.50.1820 1 262 3.5E-39 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS22075 ffdc8ca59f63fce42dcca62a679ac9d6 266 Pfam PF12697 Alpha/beta hydrolase family 12 247 1.0E-14 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS22075 ffdc8ca59f63fce42dcca62a679ac9d6 266 PRINTS PR00412 Epoxide hydrolase signature 82 95 1.9E-6 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS22075 ffdc8ca59f63fce42dcca62a679ac9d6 266 PRINTS PR00412 Epoxide hydrolase signature 38 53 1.9E-6 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS22075 ffdc8ca59f63fce42dcca62a679ac9d6 266 PRINTS PR00412 Epoxide hydrolase signature 96 109 1.9E-6 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS22075 ffdc8ca59f63fce42dcca62a679ac9d6 266 PRINTS PR00412 Epoxide hydrolase signature 232 254 1.9E-6 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS22075 ffdc8ca59f63fce42dcca62a679ac9d6 266 SUPERFAMILY SSF53474 1 255 2.9E-41 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS22075 ffdc8ca59f63fce42dcca62a679ac9d6 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 38 53 2.9E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS22075 ffdc8ca59f63fce42dcca62a679ac9d6 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 82 95 2.9E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS22075 ffdc8ca59f63fce42dcca62a679ac9d6 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 201 215 2.9E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS22075 ffdc8ca59f63fce42dcca62a679ac9d6 266 ProSitePatterns PS00131 Serine carboxypeptidases, serine active site. 82 89 - T 28-03-2018 IPR018202 Serine carboxypeptidase, serine active site CU254_RS08695 e6daae33402f162e2e689968afac6c31 400 Pfam PF03734 L,D-transpeptidase catalytic domain 254 369 7.2E-14 T 28-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CU254_RS08695 e6daae33402f162e2e689968afac6c31 400 Gene3D G3DSA:2.40.440.10 236 371 4.4E-21 T 28-03-2018 CU254_RS08695 e6daae33402f162e2e689968afac6c31 400 SUPERFAMILY SSF141523 243 369 3.14E-24 T 28-03-2018 CU254_RS14910 44e3470df98f0f04000c84123746a6dc 218 SUPERFAMILY SSF46785 11 82 2.77E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS14910 44e3470df98f0f04000c84123746a6dc 218 Pfam PF09339 IclR helix-turn-helix domain 12 61 1.6E-13 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS14910 44e3470df98f0f04000c84123746a6dc 218 Gene3D G3DSA:1.10.10.10 1 70 6.7E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS14910 44e3470df98f0f04000c84123746a6dc 218 Gene3D G3DSA:3.30.450.40 157 218 6.6E-7 T 28-03-2018 IPR029016 GAF domain-like CU254_RS14910 44e3470df98f0f04000c84123746a6dc 218 Gene3D G3DSA:3.30.450.40 71 156 1.5E-13 T 28-03-2018 IPR029016 GAF domain-like CU254_RS14910 44e3470df98f0f04000c84123746a6dc 218 SMART SM00346 10 97 3.5E-10 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS14910 44e3470df98f0f04000c84123746a6dc 218 SUPERFAMILY SSF55781 82 216 1.96E-19 T 28-03-2018 IPR029016 GAF domain-like CU254_RS03085 03604b03269489588aefb282750cc139 149 SUPERFAMILY SSF52218 1 148 1.19E-28 T 28-03-2018 IPR029039 Flavoprotein-like domain CU254_RS03085 03604b03269489588aefb282750cc139 149 Pfam PF03358 NADPH-dependent FMN reductase 38 125 2.7E-8 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CU254_RS03085 03604b03269489588aefb282750cc139 149 Gene3D G3DSA:3.40.50.360 1 149 1.6E-22 T 28-03-2018 IPR029039 Flavoprotein-like domain CU254_RS14315 6533dc89828a49820a24c425875274c8 275 SMART SM00422 2 72 4.2E-19 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS14315 6533dc89828a49820a24c425875274c8 275 SMART SM00871 119 271 6.5E-12 T 28-03-2018 IPR010499 Bacterial transcription activator, effector binding CU254_RS14315 6533dc89828a49820a24c425875274c8 275 SUPERFAMILY SSF46955 2 115 4.76E-24 T 28-03-2018 IPR009061 Putative DNA-binding domain CU254_RS14315 6533dc89828a49820a24c425875274c8 275 SUPERFAMILY SSF55136 120 269 6.98E-15 T 28-03-2018 CU254_RS14315 6533dc89828a49820a24c425875274c8 275 Pfam PF06445 GyrI-like small molecule binding domain 120 266 1.2E-11 T 28-03-2018 IPR029442 GyrI-like small molecule binding domain CU254_RS14315 6533dc89828a49820a24c425875274c8 275 Gene3D G3DSA:3.20.80.10 122 272 5.8E-23 T 28-03-2018 IPR011256 Regulatory factor, effector binding domain CU254_RS14315 6533dc89828a49820a24c425875274c8 275 Gene3D G3DSA:1.10.1660.10 59 121 8.2E-8 T 28-03-2018 CU254_RS14315 6533dc89828a49820a24c425875274c8 275 Gene3D G3DSA:1.10.1660.10 1 58 2.1E-18 T 28-03-2018 CU254_RS14315 6533dc89828a49820a24c425875274c8 275 Pfam PF13411 MerR HTH family regulatory protein 2 71 4.2E-13 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS09630 bac3ab2efac30cbe094468483e63a05d 418 SUPERFAMILY SSF56349 96 397 5.0E-38 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CU254_RS09630 bac3ab2efac30cbe094468483e63a05d 418 Gene3D G3DSA:1.10.150.130 86 197 5.9E-11 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CU254_RS09630 bac3ab2efac30cbe094468483e63a05d 418 Pfam PF00589 Phage integrase family 206 393 1.1E-11 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CU254_RS09630 bac3ab2efac30cbe094468483e63a05d 418 Gene3D G3DSA:1.10.443.10 198 410 2.9E-27 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CU254_RS21680 762365f81cae089691ed9b4d881862f2 312 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 222 310 5.3E-28 T 28-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CU254_RS21680 762365f81cae089691ed9b4d881862f2 312 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 5 310 5.0E-92 T 28-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CU254_RS21680 762365f81cae089691ed9b4d881862f2 312 Gene3D G3DSA:3.40.47.10 3 200 8.3E-49 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS21680 762365f81cae089691ed9b4d881862f2 312 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 2 311 56.055 T 28-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CU254_RS21680 762365f81cae089691ed9b4d881862f2 312 Gene3D G3DSA:3.40.47.10 201 311 2.0E-25 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS21680 762365f81cae089691ed9b4d881862f2 312 SUPERFAMILY SSF53901 2 311 7.74E-60 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS21680 762365f81cae089691ed9b4d881862f2 312 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 107 181 5.6E-26 T 28-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CU254_RS01520 5a38f8fe845effbc9b995add1856c416 269 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 120 201 1.6E-12 T 28-03-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 CU254_RS01520 5a38f8fe845effbc9b995add1856c416 269 SMART SM00702 31 218 0.0057 T 28-03-2018 IPR006620 Prolyl 4-hydroxylase, alpha subunit GO:0005506|GO:0016705|GO:0031418|GO:0055114 CU254_RS01520 5a38f8fe845effbc9b995add1856c416 269 Gene3D G3DSA:2.60.120.620 20 225 6.2E-13 T 28-03-2018 CU254_RS02665 567eedc31bd4c1ee44e66b28979bec1c 284 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 120 3.8E-35 T 28-03-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CU254_RS02665 567eedc31bd4c1ee44e66b28979bec1c 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 3.1E-60 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CU254_RS02665 567eedc31bd4c1ee44e66b28979bec1c 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 3.1E-60 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CU254_RS02665 567eedc31bd4c1ee44e66b28979bec1c 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 3.1E-60 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CU254_RS02665 567eedc31bd4c1ee44e66b28979bec1c 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 3.1E-60 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CU254_RS02665 567eedc31bd4c1ee44e66b28979bec1c 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 205 234 3.1E-60 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CU254_RS02665 567eedc31bd4c1ee44e66b28979bec1c 284 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 255 273 3.1E-60 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CU254_RS02665 567eedc31bd4c1ee44e66b28979bec1c 284 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 124 281 1.3E-58 T 28-03-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CU254_RS02665 567eedc31bd4c1ee44e66b28979bec1c 284 SUPERFAMILY SSF51735 123 280 1.35E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS02665 567eedc31bd4c1ee44e66b28979bec1c 284 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 282 35.815 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CU254_RS02665 567eedc31bd4c1ee44e66b28979bec1c 284 SUPERFAMILY SSF53223 2 121 3.55E-37 T 28-03-2018 CU254_RS02665 567eedc31bd4c1ee44e66b28979bec1c 284 Gene3D G3DSA:3.40.50.720 140 263 1.1E-28 T 28-03-2018 CU254_RS02665 567eedc31bd4c1ee44e66b28979bec1c 284 Gene3D G3DSA:3.40.50.10860 13 139 6.6E-40 T 28-03-2018 CU254_RS34460 aab2cdfdb0f9ceffd181c15eb93d489a 290 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 2.9E-22 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS34460 aab2cdfdb0f9ceffd181c15eb93d489a 290 Gene3D G3DSA:3.40.190.10 173 261 1.1E-5 T 28-03-2018 CU254_RS34460 aab2cdfdb0f9ceffd181c15eb93d489a 290 Gene3D G3DSA:3.40.190.10 86 172 1.4E-8 T 28-03-2018 CU254_RS34460 aab2cdfdb0f9ceffd181c15eb93d489a 290 SUPERFAMILY SSF53850 91 282 6.36E-16 T 28-03-2018 CU254_RS34460 aab2cdfdb0f9ceffd181c15eb93d489a 290 Gene3D G3DSA:1.10.10.10 1 83 3.9E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS34460 aab2cdfdb0f9ceffd181c15eb93d489a 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.0E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS34460 aab2cdfdb0f9ceffd181c15eb93d489a 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.0E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS34460 aab2cdfdb0f9ceffd181c15eb93d489a 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.0E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS34460 aab2cdfdb0f9ceffd181c15eb93d489a 290 SUPERFAMILY SSF46785 2 85 2.72E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS34460 aab2cdfdb0f9ceffd181c15eb93d489a 290 Pfam PF03466 LysR substrate binding domain 87 285 3.6E-14 T 28-03-2018 IPR005119 LysR, substrate-binding CU254_RS18780 c59f07bea6a6736548ba24cce0ebd7cc 303 Gene3D G3DSA:3.60.10.10 89 298 4.6E-21 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CU254_RS18780 c59f07bea6a6736548ba24cce0ebd7cc 303 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 102 290 1.1E-11 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CU254_RS18780 c59f07bea6a6736548ba24cce0ebd7cc 303 SUPERFAMILY SSF56219 100 297 2.75E-23 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CU254_RS28500 f8277745ff249fc4a8517b6daf9d79b1 659 TIGRFAM TIGR02442 Cob-chelat-sub: cobaltochelatase subunit 4 639 3.7E-239 T 28-03-2018 IPR012804 Cobaltochelatase subunit, putative CU254_RS28500 f8277745ff249fc4a8517b6daf9d79b1 659 Gene3D G3DSA:3.40.50.410 466 655 3.0E-27 T 28-03-2018 IPR002035 von Willebrand factor, type A CU254_RS28500 f8277745ff249fc4a8517b6daf9d79b1 659 Pfam PF01078 Magnesium chelatase, subunit ChlI 113 182 3.8E-8 T 28-03-2018 IPR000523 Magnesium chelatase ChlI domain CU254_RS28500 f8277745ff249fc4a8517b6daf9d79b1 659 SMART SM00327 477 657 5.7E-17 T 28-03-2018 IPR002035 von Willebrand factor, type A CU254_RS28500 f8277745ff249fc4a8517b6daf9d79b1 659 Pfam PF13519 von Willebrand factor type A domain 480 586 1.2E-13 T 28-03-2018 IPR002035 von Willebrand factor, type A CU254_RS28500 f8277745ff249fc4a8517b6daf9d79b1 659 Gene3D G3DSA:1.10.8.80 247 335 1.4E-25 T 28-03-2018 CU254_RS28500 f8277745ff249fc4a8517b6daf9d79b1 659 Gene3D G3DSA:3.40.50.300 2 202 5.1E-24 T 28-03-2018 CU254_RS28500 f8277745ff249fc4a8517b6daf9d79b1 659 SUPERFAMILY SSF53300 480 641 1.08E-21 T 28-03-2018 IPR002035 von Willebrand factor, type A CU254_RS28500 f8277745ff249fc4a8517b6daf9d79b1 659 SUPERFAMILY SSF52540 2 326 3.93E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS28500 f8277745ff249fc4a8517b6daf9d79b1 659 SMART SM00382 27 205 1.0E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS35665 397cca12ecb2357d9650a2cba2c8a0f9 167 Gene3D G3DSA:1.10.1740.10 4 75 7.1E-10 T 28-03-2018 CU254_RS35665 397cca12ecb2357d9650a2cba2c8a0f9 167 Pfam PF04545 Sigma-70, region 4 112 157 6.2E-7 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS35665 397cca12ecb2357d9650a2cba2c8a0f9 167 Pfam PF04542 Sigma-70 region 2 16 73 3.9E-8 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS35665 397cca12ecb2357d9650a2cba2c8a0f9 167 SUPERFAMILY SSF88946 24 92 3.77E-9 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS35665 397cca12ecb2357d9650a2cba2c8a0f9 167 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 23 159 4.2E-21 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS35665 397cca12ecb2357d9650a2cba2c8a0f9 167 Gene3D G3DSA:1.10.10.10 79 165 1.5E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS35665 397cca12ecb2357d9650a2cba2c8a0f9 167 SUPERFAMILY SSF88659 85 162 2.8E-13 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS06275 1b5169af7ab106182250917eea39dc09 675 Pfam PF01575 MaoC like domain 538 640 4.9E-20 T 28-03-2018 IPR002539 MaoC-like domain CU254_RS06275 1b5169af7ab106182250917eea39dc09 675 Gene3D G3DSA:3.40.605.10 3 266 9.3E-42 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CU254_RS06275 1b5169af7ab106182250917eea39dc09 675 SUPERFAMILY SSF53720 3 502 1.83E-79 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CU254_RS06275 1b5169af7ab106182250917eea39dc09 675 Pfam PF00171 Aldehyde dehydrogenase family 17 440 6.3E-61 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CU254_RS06275 1b5169af7ab106182250917eea39dc09 675 Gene3D G3DSA:3.10.129.10 502 671 4.8E-37 T 28-03-2018 CU254_RS06275 1b5169af7ab106182250917eea39dc09 675 SUPERFAMILY SSF54637 528 673 1.43E-33 T 28-03-2018 IPR029069 HotDog domain CU254_RS06275 1b5169af7ab106182250917eea39dc09 675 TIGRFAM TIGR02278 PaaN-DH: phenylacetic acid degradation protein paaN 4 672 1.4E-298 T 28-03-2018 IPR011966 Phenylacetic acid degradation protein PaaN KEGG: 00360+3.3.2.12+1.2.1.91 CU254_RS06275 1b5169af7ab106182250917eea39dc09 675 Gene3D G3DSA:3.40.309.10 267 487 1.3E-34 T 28-03-2018 CU254_RS21695 7bf2bd34e6d6d71ed77633e6434fc961 196 SUPERFAMILY SSF46689 2 58 1.95E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS21695 7bf2bd34e6d6d71ed77633e6434fc961 196 SUPERFAMILY SSF48498 66 169 3.42E-22 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS21695 7bf2bd34e6d6d71ed77633e6434fc961 196 Gene3D G3DSA:1.10.357.10 69 189 8.0E-16 T 28-03-2018 CU254_RS21695 7bf2bd34e6d6d71ed77633e6434fc961 196 Gene3D G3DSA:1.10.10.60 1 68 4.0E-6 T 28-03-2018 CU254_RS28615 25e20c02c2f5a17072ff03fc197d8a0c 338 Gene3D G3DSA:1.20.5.400 10 132 7.7E-5 T 28-03-2018 CU254_RS28615 25e20c02c2f5a17072ff03fc197d8a0c 338 Pfam PF06259 Alpha/beta hydrolase 88 256 1.8E-28 T 28-03-2018 IPR010427 Protein of unknown function DUF1023 CU254_RS40140 2f3c4eb95467a49ffaa7bd281a98311e 413 SUPERFAMILY SSF103473 10 395 1.96E-43 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS40140 2f3c4eb95467a49ffaa7bd281a98311e 413 Pfam PF05977 Transmembrane secretion effector 10 396 3.8E-26 T 28-03-2018 IPR010290 Transmembrane secretion effector CU254_RS40140 2f3c4eb95467a49ffaa7bd281a98311e 413 Gene3D G3DSA:1.20.1250.20 5 202 8.8E-18 T 28-03-2018 CU254_RS40140 2f3c4eb95467a49ffaa7bd281a98311e 413 Gene3D G3DSA:1.20.1250.20 203 397 9.4E-18 T 28-03-2018 CU254_RS24610 9805c61ee7e70e12f2430617f78fece8 519 Pfam PF02875 Mur ligase family, glutamate ligase domain 354 439 1.2E-20 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CU254_RS24610 9805c61ee7e70e12f2430617f78fece8 519 Gene3D G3DSA:3.40.1190.10 127 357 2.1E-56 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CU254_RS24610 9805c61ee7e70e12f2430617f78fece8 519 SUPERFAMILY SSF53623 127 352 1.08E-64 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CU254_RS24610 9805c61ee7e70e12f2430617f78fece8 519 Gene3D G3DSA:3.40.1390.10 20 126 3.8E-23 T 28-03-2018 CU254_RS24610 9805c61ee7e70e12f2430617f78fece8 519 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 21 511 32.055 T 28-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 CU254_RS24610 9805c61ee7e70e12f2430617f78fece8 519 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 43 511 1.5E-143 T 28-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 CU254_RS24610 9805c61ee7e70e12f2430617f78fece8 519 SUPERFAMILY SSF53244 354 513 1.83E-47 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CU254_RS24610 9805c61ee7e70e12f2430617f78fece8 519 SUPERFAMILY SSF63418 40 125 2.22E-18 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CU254_RS24610 9805c61ee7e70e12f2430617f78fece8 519 Pfam PF01225 Mur ligase family, catalytic domain 46 121 7.8E-12 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CU254_RS24610 9805c61ee7e70e12f2430617f78fece8 519 Gene3D G3DSA:3.90.190.20 358 515 1.1E-47 T 28-03-2018 CU254_RS24610 9805c61ee7e70e12f2430617f78fece8 519 Pfam PF08245 Mur ligase middle domain 136 334 2.3E-43 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CU254_RS35320 794d67008320903da1000dd9f6ad9e2d 405 Gene3D G3DSA:1.10.540.10 2 124 1.5E-17 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS35320 794d67008320903da1000dd9f6ad9e2d 405 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 92 9.8E-11 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS35320 794d67008320903da1000dd9f6ad9e2d 405 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 250 364 7.2E-15 T 28-03-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain CU254_RS35320 794d67008320903da1000dd9f6ad9e2d 405 SUPERFAMILY SSF56645 3 226 3.14E-50 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS35320 794d67008320903da1000dd9f6ad9e2d 405 Gene3D G3DSA:2.40.110.10 125 218 2.8E-22 T 28-03-2018 CU254_RS35320 794d67008320903da1000dd9f6ad9e2d 405 SUPERFAMILY SSF47203 239 385 3.38E-20 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS35320 794d67008320903da1000dd9f6ad9e2d 405 Gene3D G3DSA:1.20.140.10 219 388 5.0E-22 T 28-03-2018 CU254_RS35320 794d67008320903da1000dd9f6ad9e2d 405 PIRSF PIRSF016578 2 98 4.9E-13 T 28-03-2018 CU254_RS35320 794d67008320903da1000dd9f6ad9e2d 405 PIRSF PIRSF016578 137 389 5.9E-28 T 28-03-2018 CU254_RS35320 794d67008320903da1000dd9f6ad9e2d 405 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 127 218 4.0E-13 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CU254_RS01270 f3722504ee52ffa0143393faf4b2d36d 378 SUPERFAMILY SSF56801 32 376 7.72E-76 T 28-03-2018 CU254_RS01270 f3722504ee52ffa0143393faf4b2d36d 378 Gene3D G3DSA:3.40.50.980 66 214 3.1E-25 T 28-03-2018 CU254_RS01270 f3722504ee52ffa0143393faf4b2d36d 378 Gene3D G3DSA:3.40.50.980 1 65 4.1E-7 T 28-03-2018 CU254_RS01270 f3722504ee52ffa0143393faf4b2d36d 378 Gene3D G3DSA:3.30.300.30 280 377 2.2E-25 T 28-03-2018 CU254_RS01270 f3722504ee52ffa0143393faf4b2d36d 378 ProSitePatterns PS00455 Putative AMP-binding domain signature. 60 71 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS01270 f3722504ee52ffa0143393faf4b2d36d 378 Pfam PF13193 AMP-binding enzyme C-terminal domain 296 366 1.2E-18 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS01270 f3722504ee52ffa0143393faf4b2d36d 378 Gene3D G3DSA:2.30.38.10 215 279 5.0E-13 T 28-03-2018 CU254_RS01270 f3722504ee52ffa0143393faf4b2d36d 378 Pfam PF00501 AMP-binding enzyme 45 286 4.8E-33 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS06950 9561606597adef78120364e9d03612ea 553 SUPERFAMILY SSF51569 12 304 4.58E-71 T 28-03-2018 CU254_RS06950 9561606597adef78120364e9d03612ea 553 SMART SM00917 387 535 5.6E-36 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CU254_RS06950 9561606597adef78120364e9d03612ea 553 Pfam PF00682 HMGL-like 16 267 5.3E-40 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CU254_RS06950 9561606597adef78120364e9d03612ea 553 Gene3D G3DSA:3.20.20.70 3 362 1.4E-84 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS06950 9561606597adef78120364e9d03612ea 553 TIGRFAM TIGR00977 citramal_synth: citramalate synthase 16 534 2.5E-172 T 28-03-2018 IPR005675 Citramalate synthase GO:0019752|GO:0046912 KEGG: 00290+2.3.1.182|KEGG: 00660+2.3.1.182|MetaCyc: PWY-5101 CU254_RS06950 9561606597adef78120364e9d03612ea 553 SUPERFAMILY SSF110921 414 531 1.83E-26 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CU254_RS06950 9561606597adef78120364e9d03612ea 553 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 22 38 - T 28-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CU254_RS06950 9561606597adef78120364e9d03612ea 553 Pfam PF08502 LeuA allosteric (dimerisation) domain 388 532 5.1E-26 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CU254_RS14200 a9f358d36e8b998c4d80f06d621eba32 331 Pfam PF13354 Beta-lactamase enzyme family 100 303 9.8E-40 T 28-03-2018 CU254_RS14200 a9f358d36e8b998c4d80f06d621eba32 331 PRINTS PR00118 Beta-lactamase class A signature 110 127 2.7E-59 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CU254_RS14200 a9f358d36e8b998c4d80f06d621eba32 331 PRINTS PR00118 Beta-lactamase class A signature 210 235 2.7E-59 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CU254_RS14200 a9f358d36e8b998c4d80f06d621eba32 331 PRINTS PR00118 Beta-lactamase class A signature 263 278 2.7E-59 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CU254_RS14200 a9f358d36e8b998c4d80f06d621eba32 331 PRINTS PR00118 Beta-lactamase class A signature 79 103 2.7E-59 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CU254_RS14200 a9f358d36e8b998c4d80f06d621eba32 331 PRINTS PR00118 Beta-lactamase class A signature 246 261 2.7E-59 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CU254_RS14200 a9f358d36e8b998c4d80f06d621eba32 331 PRINTS PR00118 Beta-lactamase class A signature 184 208 2.7E-59 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CU254_RS14200 a9f358d36e8b998c4d80f06d621eba32 331 PRINTS PR00118 Beta-lactamase class A signature 148 173 2.7E-59 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CU254_RS14200 a9f358d36e8b998c4d80f06d621eba32 331 ProSitePatterns PS00146 Beta-lactamase class-A active site. 112 127 - T 28-03-2018 IPR023650 Beta-lactamase, class-A active site KEGG: 00311+3.5.2.6 CU254_RS14200 a9f358d36e8b998c4d80f06d621eba32 331 Gene3D G3DSA:3.40.710.10 77 330 3.3E-35 T 28-03-2018 CU254_RS14200 a9f358d36e8b998c4d80f06d621eba32 331 SUPERFAMILY SSF56601 79 328 3.7E-73 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CU254_RS22670 fdbd6b436e19eb5637a5795ba65bc8e0 125 Gene3D G3DSA:3.10.450.50 3 125 6.0E-44 T 28-03-2018 CU254_RS22670 fdbd6b436e19eb5637a5795ba65bc8e0 125 Hamap MF_00612 UPF0225 protein YchJ [ychJ]. 1 124 27.914 T 28-03-2018 IPR023006 Uncharacterised protein family UPF0225 CU254_RS22670 fdbd6b436e19eb5637a5795ba65bc8e0 125 SUPERFAMILY SSF54427 25 122 1.97E-33 T 28-03-2018 IPR032710 NTF2-like domain CU254_RS23595 53d6cad7703a732930d8d6197dd09880 189 Gene3D G3DSA:2.20.25.90 37 102 1.9E-25 T 28-03-2018 CU254_RS23595 53d6cad7703a732930d8d6197dd09880 189 SUPERFAMILY SSF53706 43 189 6.15E-49 T 28-03-2018 CU254_RS23595 53d6cad7703a732930d8d6197dd09880 189 SMART SM00926 44 98 1.8E-22 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS23595 53d6cad7703a732930d8d6197dd09880 189 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 45 96 8.6E-20 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS23595 53d6cad7703a732930d8d6197dd09880 189 Gene3D G3DSA:3.40.50.740 103 189 1.6E-9 T 28-03-2018 CU254_RS02130 9da000a184ec34efd51515c8e6409870 410 TIGRFAM TIGR03923 T7SS_EccE: type VII secretion protein EccE 17 408 3.6E-57 T 28-03-2018 IPR021368 Type VII secretion system protein EccE CU254_RS02130 9da000a184ec34efd51515c8e6409870 410 Pfam PF11203 Putative type VII ESX secretion system translocon, EccE 215 317 1.8E-24 T 28-03-2018 IPR021368 Type VII secretion system protein EccE CU254_RS14610 e5e79c2f9895cf0c20cd28f845bd1c45 250 SUPERFAMILY SSF46785 15 87 3.5E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS14610 e5e79c2f9895cf0c20cd28f845bd1c45 250 Pfam PF07729 FCD domain 106 229 1.3E-22 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS14610 e5e79c2f9895cf0c20cd28f845bd1c45 250 Pfam PF00392 Bacterial regulatory proteins, gntR family 24 83 2.5E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS14610 e5e79c2f9895cf0c20cd28f845bd1c45 250 SMART SM00895 106 232 3.6E-17 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS14610 e5e79c2f9895cf0c20cd28f845bd1c45 250 SMART SM00345 24 83 3.8E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS14610 e5e79c2f9895cf0c20cd28f845bd1c45 250 SUPERFAMILY SSF48008 103 236 3.4E-23 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS14610 e5e79c2f9895cf0c20cd28f845bd1c45 250 Gene3D G3DSA:1.20.120.530 94 239 4.9E-27 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS14610 e5e79c2f9895cf0c20cd28f845bd1c45 250 Gene3D G3DSA:1.10.10.10 12 84 2.9E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS08925 9e7d0f11a19c9039806de746c5f43aaf 572 SUPERFAMILY SSF53098 20 206 2.24E-55 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS08925 9e7d0f11a19c9039806de746c5f43aaf 572 Pfam PF00929 Exonuclease 27 183 4.6E-33 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CU254_RS08925 9e7d0f11a19c9039806de746c5f43aaf 572 SUPERFAMILY SSF82771 226 306 1.83E-15 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CU254_RS08925 9e7d0f11a19c9039806de746c5f43aaf 572 SMART SM00465 226 307 1.4E-13 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CU254_RS08925 9e7d0f11a19c9039806de746c5f43aaf 572 Gene3D G3DSA:3.40.1440.10 212 310 3.0E-20 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CU254_RS08925 9e7d0f11a19c9039806de746c5f43aaf 572 Gene3D G3DSA:3.30.420.10 19 177 1.0E-40 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS08925 9e7d0f11a19c9039806de746c5f43aaf 572 Gene3D G3DSA:1.20.5.140 178 196 1.4E-6 T 28-03-2018 CU254_RS08925 9e7d0f11a19c9039806de746c5f43aaf 572 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 21 195 1.5E-30 T 28-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CU254_RS08925 9e7d0f11a19c9039806de746c5f43aaf 572 Pfam PF01541 GIY-YIG catalytic domain 228 302 3.7E-6 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CU254_RS08925 9e7d0f11a19c9039806de746c5f43aaf 572 SMART SM00479 25 193 7.7E-53 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CU254_RS35745 b5a226e1cf225692971cd7b6c9297f2f 222 Gene3D G3DSA:3.40.50.2300 1 119 1.4E-34 T 28-03-2018 CU254_RS35745 b5a226e1cf225692971cd7b6c9297f2f 222 SUPERFAMILY SSF52172 1 172 1.96E-39 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS35745 b5a226e1cf225692971cd7b6c9297f2f 222 Pfam PF00072 Response regulator receiver domain 4 112 2.0E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS35745 b5a226e1cf225692971cd7b6c9297f2f 222 Gene3D G3DSA:1.10.10.10 120 222 6.0E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS35745 b5a226e1cf225692971cd7b6c9297f2f 222 SMART SM00862 145 220 1.1E-23 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS35745 b5a226e1cf225692971cd7b6c9297f2f 222 SMART SM00448 1 112 2.3E-38 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS35745 b5a226e1cf225692971cd7b6c9297f2f 222 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 220 1.5E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS00585 25edb68b433b6542f7a9d25b51b19b12 820 Gene3D G3DSA:1.25.40.10 487 640 4.9E-22 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS00585 25edb68b433b6542f7a9d25b51b19b12 820 Pfam PF00069 Protein kinase domain 212 411 8.7E-28 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CU254_RS00585 25edb68b433b6542f7a9d25b51b19b12 820 SMART SM00220 211 466 4.1E-19 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CU254_RS00585 25edb68b433b6542f7a9d25b51b19b12 820 SUPERFAMILY SSF48452 556 686 4.2E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS00585 25edb68b433b6542f7a9d25b51b19b12 820 Pfam PF16918 Protein kinase G tetratricopeptide repeat 482 818 4.1E-93 T 28-03-2018 IPR031636 Protein kinase G, tetratricopeptide repeat containing domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CU254_RS00585 25edb68b433b6542f7a9d25b51b19b12 820 Gene3D G3DSA:1.25.40.10 641 713 0.0011 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS00585 25edb68b433b6542f7a9d25b51b19b12 820 SUPERFAMILY SSF56112 204 462 5.39E-43 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS00585 25edb68b433b6542f7a9d25b51b19b12 820 Pfam PF16919 Protein kinase G rubredoxin domain 118 210 7.1E-29 T 28-03-2018 IPR031634 Protein kinase G, rubredoxin domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CU254_RS00585 25edb68b433b6542f7a9d25b51b19b12 820 Gene3D G3DSA:3.30.200.20 197 300 9.1E-15 T 28-03-2018 CU254_RS00585 25edb68b433b6542f7a9d25b51b19b12 820 Gene3D G3DSA:1.10.510.10 301 486 4.9E-23 T 28-03-2018 CU254_RS35015 86bc0389f8c20a465fb3cfaf2863e03f 329 SUPERFAMILY SSF101478 3 327 5.62E-64 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 CU254_RS35015 86bc0389f8c20a465fb3cfaf2863e03f 329 Gene3D G3DSA:1.10.4080.10 1 329 9.6E-67 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 CU254_RS35015 86bc0389f8c20a465fb3cfaf2863e03f 329 Pfam PF03747 ADP-ribosylglycohydrolase 9 303 8.7E-55 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 CU254_RS16270 e4e74281ec081103d99f0b1e88dc7c76 663 SMART SM00532 2 428 7.8E-135 T 28-03-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 CU254_RS16270 e4e74281ec081103d99f0b1e88dc7c76 663 PIRSF PIRSF001604 1 662 2.7E-195 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CU254_RS16270 e4e74281ec081103d99f0b1e88dc7c76 663 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 105 134 - T 28-03-2018 IPR018239 NAD-dependent DNA ligase, active site CU254_RS16270 e4e74281ec081103d99f0b1e88dc7c76 663 Gene3D G3DSA:3.40.50.10190 551 657 2.4E-10 T 28-03-2018 IPR001357 BRCT domain CU254_RS16270 e4e74281ec081103d99f0b1e88dc7c76 663 Pfam PF12826 Helix-hairpin-helix motif 491 546 4.4E-7 T 28-03-2018 CU254_RS16270 e4e74281ec081103d99f0b1e88dc7c76 663 SMART SM00278 525 544 14.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CU254_RS16270 e4e74281ec081103d99f0b1e88dc7c76 663 SMART SM00278 460 479 26.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CU254_RS16270 e4e74281ec081103d99f0b1e88dc7c76 663 Gene3D G3DSA:1.10.287.610 1 65 1.5E-13 T 28-03-2018 CU254_RS16270 e4e74281ec081103d99f0b1e88dc7c76 663 SUPERFAMILY SSF56091 2 298 8.78E-73 T 28-03-2018 CU254_RS16270 e4e74281ec081103d99f0b1e88dc7c76 663 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 10 650 8.3E-170 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CU254_RS16270 e4e74281ec081103d99f0b1e88dc7c76 663 SUPERFAMILY SSF52113 578 655 1.35E-8 T 28-03-2018 IPR001357 BRCT domain CU254_RS16270 e4e74281ec081103d99f0b1e88dc7c76 663 Gene3D G3DSA:1.10.150.20 483 549 5.3E-12 T 28-03-2018 CU254_RS16270 e4e74281ec081103d99f0b1e88dc7c76 663 SUPERFAMILY SSF47781 385 562 1.11E-41 T 28-03-2018 IPR010994 RuvA domain 2-like CU254_RS16270 e4e74281ec081103d99f0b1e88dc7c76 663 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 301 376 1.4E-27 T 28-03-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 CU254_RS16270 e4e74281ec081103d99f0b1e88dc7c76 663 Gene3D G3DSA:3.30.470.30 109 250 5.2E-33 T 28-03-2018 CU254_RS16270 e4e74281ec081103d99f0b1e88dc7c76 663 SMART SM00292 576 660 8.0E-5 T 28-03-2018 IPR001357 BRCT domain CU254_RS16270 e4e74281ec081103d99f0b1e88dc7c76 663 Gene3D G3DSA:2.40.50.140 297 370 3.4E-28 T 28-03-2018 CU254_RS16270 e4e74281ec081103d99f0b1e88dc7c76 663 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 3 298 1.1E-66 T 28-03-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 CU254_RS16270 e4e74281ec081103d99f0b1e88dc7c76 663 Hamap MF_01588 DNA ligase [ligA]. 1 657 47.912 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CU254_RS16270 e4e74281ec081103d99f0b1e88dc7c76 663 Gene3D G3DSA:1.10.150.20 412 482 1.6E-20 T 28-03-2018 CU254_RS16270 e4e74281ec081103d99f0b1e88dc7c76 663 SUPERFAMILY SSF50249 297 376 8.91E-24 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CU254_RS27205 22169de53cb12aef27d7215305d016b9 1574 Gene3D G3DSA:2.60.120.260 225 316 4.9E-24 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS27205 22169de53cb12aef27d7215305d016b9 1574 Gene3D G3DSA:2.60.120.260 868 914 0.38 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS27205 22169de53cb12aef27d7215305d016b9 1574 Gene3D G3DSA:2.60.120.260 92 224 4.7E-14 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS27205 22169de53cb12aef27d7215305d016b9 1574 Gene3D G3DSA:2.60.120.260 686 775 3.2E-18 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS27205 22169de53cb12aef27d7215305d016b9 1574 Gene3D G3DSA:2.60.120.260 317 407 3.9E-23 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS27205 22169de53cb12aef27d7215305d016b9 1574 Gene3D G3DSA:2.60.120.260 408 499 9.5E-24 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS27205 22169de53cb12aef27d7215305d016b9 1574 Gene3D G3DSA:2.60.120.260 776 867 1.4E-22 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS27205 22169de53cb12aef27d7215305d016b9 1574 Gene3D G3DSA:2.60.120.260 592 685 4.8E-22 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS27205 22169de53cb12aef27d7215305d016b9 1574 Gene3D G3DSA:2.60.120.260 500 591 3.7E-24 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS27205 22169de53cb12aef27d7215305d016b9 1574 SUPERFAMILY SSF58104 151 317 7.59E-9 T 28-03-2018 CU254_RS27205 22169de53cb12aef27d7215305d016b9 1574 SUPERFAMILY SSF58104 325 640 3.4E-21 T 28-03-2018 CU254_RS27205 22169de53cb12aef27d7215305d016b9 1574 Gene3D G3DSA:3.30.450.40 915 1118 4.6E-25 T 28-03-2018 IPR029016 GAF domain-like CU254_RS27205 22169de53cb12aef27d7215305d016b9 1574 SMART SM00304 489 541 3.3E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS27205 22169de53cb12aef27d7215305d016b9 1574 SMART SM00304 305 357 2.4E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS27205 22169de53cb12aef27d7215305d016b9 1574 SMART SM00304 765 817 1.1E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS27205 22169de53cb12aef27d7215305d016b9 1574 SMART SM00304 673 725 1.7E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS27205 22169de53cb12aef27d7215305d016b9 1574 SMART SM00304 213 265 1.3E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS27205 22169de53cb12aef27d7215305d016b9 1574 SMART SM00304 581 633 1.7E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS27205 22169de53cb12aef27d7215305d016b9 1574 SMART SM00304 24 76 12.0 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS27205 22169de53cb12aef27d7215305d016b9 1574 SMART SM00304 857 909 8.8E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS27205 22169de53cb12aef27d7215305d016b9 1574 SMART SM00304 397 449 5.9E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS27205 22169de53cb12aef27d7215305d016b9 1574 SMART SM00304 116 173 7.6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS27205 22169de53cb12aef27d7215305d016b9 1574 Gene3D G3DSA:1.10.287.130 1141 1221 1.3E-14 T 28-03-2018 CU254_RS27205 22169de53cb12aef27d7215305d016b9 1574 SUPERFAMILY SSF55874 1214 1394 9.56E-46 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS27205 22169de53cb12aef27d7215305d016b9 1574 SUPERFAMILY SSF58104 601 781 6.28E-12 T 28-03-2018 CU254_RS27205 22169de53cb12aef27d7215305d016b9 1574 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 1272 1394 5.0E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS27205 22169de53cb12aef27d7215305d016b9 1574 Pfam PF00072 Response regulator receiver domain 1436 1548 1.9E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS27205 22169de53cb12aef27d7215305d016b9 1574 SMART SM00448 1434 1548 1.6E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS27205 22169de53cb12aef27d7215305d016b9 1574 SUPERFAMILY SSF58104 785 908 5.75E-11 T 28-03-2018 CU254_RS27205 22169de53cb12aef27d7215305d016b9 1574 Pfam PF13185 GAF domain 932 1070 2.1E-16 T 28-03-2018 IPR003018 GAF domain GO:0005515 CU254_RS27205 22169de53cb12aef27d7215305d016b9 1574 SMART SM00388 1157 1225 2.8E-20 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS27205 22169de53cb12aef27d7215305d016b9 1574 SMART SM00387 1272 1396 1.2E-39 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS27205 22169de53cb12aef27d7215305d016b9 1574 SMART SM00065 933 1082 9.6E-4 T 28-03-2018 IPR003018 GAF domain GO:0005515 CU254_RS27205 22169de53cb12aef27d7215305d016b9 1574 Pfam PF00512 His Kinase A (phospho-acceptor) domain 1158 1225 3.1E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS27205 22169de53cb12aef27d7215305d016b9 1574 SUPERFAMILY SSF52172 1428 1558 4.27E-34 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS27205 22169de53cb12aef27d7215305d016b9 1574 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1321 1335 4.1E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS27205 22169de53cb12aef27d7215305d016b9 1574 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1380 1393 4.1E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS27205 22169de53cb12aef27d7215305d016b9 1574 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1339 1349 4.1E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS27205 22169de53cb12aef27d7215305d016b9 1574 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1356 1374 4.1E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS27205 22169de53cb12aef27d7215305d016b9 1574 Pfam PF00672 HAMP domain 679 722 4.2E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS27205 22169de53cb12aef27d7215305d016b9 1574 Pfam PF00672 HAMP domain 311 352 2.4E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS27205 22169de53cb12aef27d7215305d016b9 1574 Gene3D G3DSA:3.40.50.2300 1430 1573 5.7E-34 T 28-03-2018 CU254_RS27205 22169de53cb12aef27d7215305d016b9 1574 Gene3D G3DSA:3.30.565.10 1229 1400 5.8E-47 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS27205 22169de53cb12aef27d7215305d016b9 1574 SUPERFAMILY SSF55781 896 1070 9.42E-26 T 28-03-2018 IPR029016 GAF domain-like CU254_RS27205 22169de53cb12aef27d7215305d016b9 1574 SUPERFAMILY SSF47384 1142 1226 3.92E-19 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS05375 f3cd08d51b3c28a0a87a2fdcc9a6eb76 158 Gene3D G3DSA:1.10.10.10 7 144 5.5E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS05375 f3cd08d51b3c28a0a87a2fdcc9a6eb76 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 121 141 4.6E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS05375 f3cd08d51b3c28a0a87a2fdcc9a6eb76 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 55 71 4.6E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS05375 f3cd08d51b3c28a0a87a2fdcc9a6eb76 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 72 87 4.6E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS05375 f3cd08d51b3c28a0a87a2fdcc9a6eb76 158 PRINTS PR00598 Bacterial regulatory protein MarR family signature 91 107 4.6E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS05375 f3cd08d51b3c28a0a87a2fdcc9a6eb76 158 SUPERFAMILY SSF46785 14 142 4.12E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS05375 f3cd08d51b3c28a0a87a2fdcc9a6eb76 158 SMART SM00347 31 131 1.7E-19 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS05375 f3cd08d51b3c28a0a87a2fdcc9a6eb76 158 Pfam PF01047 MarR family 43 95 1.3E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS20990 737f9656c6dc28a18624e4472d49a9c8 879 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 91 416 3.6E-73 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CU254_RS20990 737f9656c6dc28a18624e4472d49a9c8 879 SUPERFAMILY SSF52279 455 663 8.24E-39 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CU254_RS20990 737f9656c6dc28a18624e4472d49a9c8 879 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 455 662 2.8E-28 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CU254_RS20990 737f9656c6dc28a18624e4472d49a9c8 879 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 339 356 - T 28-03-2018 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 CU254_RS20990 737f9656c6dc28a18624e4472d49a9c8 879 Gene3D G3DSA:3.20.20.300 71 434 1.9E-105 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CU254_RS20990 737f9656c6dc28a18624e4472d49a9c8 879 Gene3D G3DSA:2.60.120.430 686 863 5.4E-22 T 28-03-2018 CU254_RS20990 737f9656c6dc28a18624e4472d49a9c8 879 Gene3D G3DSA:3.40.50.1700 440 663 4.6E-41 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CU254_RS20990 737f9656c6dc28a18624e4472d49a9c8 879 PRINTS PR00133 Glycosyl hydrolase family 3 signature 177 196 1.2E-20 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CU254_RS20990 737f9656c6dc28a18624e4472d49a9c8 879 PRINTS PR00133 Glycosyl hydrolase family 3 signature 153 169 1.2E-20 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CU254_RS20990 737f9656c6dc28a18624e4472d49a9c8 879 PRINTS PR00133 Glycosyl hydrolase family 3 signature 223 239 1.2E-20 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CU254_RS20990 737f9656c6dc28a18624e4472d49a9c8 879 PRINTS PR00133 Glycosyl hydrolase family 3 signature 262 278 1.2E-20 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CU254_RS20990 737f9656c6dc28a18624e4472d49a9c8 879 PRINTS PR00133 Glycosyl hydrolase family 3 signature 339 357 1.2E-20 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CU254_RS20990 737f9656c6dc28a18624e4472d49a9c8 879 SUPERFAMILY SSF51445 79 453 3.51E-101 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS21985 840cfbc8ef53522ef6fe9b7d75ee1d5a 714 SMART SM00642 166 572 8.5E-7 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CU254_RS21985 840cfbc8ef53522ef6fe9b7d75ee1d5a 714 SUPERFAMILY SSF51445 504 579 2.46E-125 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS21985 840cfbc8ef53522ef6fe9b7d75ee1d5a 714 SUPERFAMILY SSF51445 153 475 2.46E-125 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS21985 840cfbc8ef53522ef6fe9b7d75ee1d5a 714 Gene3D G3DSA:3.20.20.80 150 584 7.5E-106 T 28-03-2018 CU254_RS21985 840cfbc8ef53522ef6fe9b7d75ee1d5a 714 SUPERFAMILY SSF81296 14 112 6.0E-35 T 28-03-2018 IPR014756 Immunoglobulin E-set CU254_RS21985 840cfbc8ef53522ef6fe9b7d75ee1d5a 714 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 18 104 9.5E-18 T 28-03-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077 CU254_RS21985 840cfbc8ef53522ef6fe9b7d75ee1d5a 714 Gene3D G3DSA:2.60.40.10 13 145 1.9E-41 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS21985 840cfbc8ef53522ef6fe9b7d75ee1d5a 714 Gene3D G3DSA:2.60.40.1180 585 707 5.6E-25 T 28-03-2018 CU254_RS21985 840cfbc8ef53522ef6fe9b7d75ee1d5a 714 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 14 703 5.4E-264 T 28-03-2018 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 CU254_RS21985 840cfbc8ef53522ef6fe9b7d75ee1d5a 714 Pfam PF00128 Alpha amylase, catalytic domain 199 280 1.3E-4 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CU254_RS21985 840cfbc8ef53522ef6fe9b7d75ee1d5a 714 SUPERFAMILY SSF51011 592 704 3.45E-16 T 28-03-2018 CU254_RS32445 ab55413aa55623769b4bb2a85cb35630 212 Pfam PF00156 Phosphoribosyl transferase domain 31 209 9.7E-7 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CU254_RS32445 ab55413aa55623769b4bb2a85cb35630 212 Gene3D G3DSA:3.40.50.2020 42 212 8.1E-22 T 28-03-2018 CU254_RS32445 ab55413aa55623769b4bb2a85cb35630 212 SUPERFAMILY SSF53271 39 211 1.7E-18 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CU254_RS30070 5fde447e958cca3a68bbbc865ff89abb 255 SUPERFAMILY SSF52540 15 231 2.55E-66 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS30070 5fde447e958cca3a68bbbc865ff89abb 255 Pfam PF00005 ABC transporter 34 179 5.5E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS30070 5fde447e958cca3a68bbbc865ff89abb 255 Gene3D G3DSA:3.40.50.300 11 254 1.2E-61 T 28-03-2018 CU254_RS30070 5fde447e958cca3a68bbbc865ff89abb 255 SMART SM00382 42 227 6.2E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS30070 5fde447e958cca3a68bbbc865ff89abb 255 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS38115 e50a449b506c2b5beed353ac5b18fff2 175 SUPERFAMILY SSF46785 13 154 9.31E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS38115 e50a449b506c2b5beed353ac5b18fff2 175 SMART SM00347 39 139 3.7E-21 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS38115 e50a449b506c2b5beed353ac5b18fff2 175 Gene3D G3DSA:1.10.10.10 2 159 1.1E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS38115 e50a449b506c2b5beed353ac5b18fff2 175 ProSitePatterns PS01117 MarR-type HTH domain signature. 78 112 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CU254_RS38115 e50a449b506c2b5beed353ac5b18fff2 175 PRINTS PR00598 Bacterial regulatory protein MarR family signature 63 79 4.9E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS38115 e50a449b506c2b5beed353ac5b18fff2 175 PRINTS PR00598 Bacterial regulatory protein MarR family signature 129 149 4.9E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS38115 e50a449b506c2b5beed353ac5b18fff2 175 PRINTS PR00598 Bacterial regulatory protein MarR family signature 99 115 4.9E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS38115 e50a449b506c2b5beed353ac5b18fff2 175 PRINTS PR00598 Bacterial regulatory protein MarR family signature 80 95 4.9E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS38115 e50a449b506c2b5beed353ac5b18fff2 175 Pfam PF01047 MarR family 48 103 5.1E-15 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS16535 abfee5f8aded52d7b6e65a58bb196038 450 Pfam PF00067 Cytochrome P450 280 419 4.9E-20 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS16535 abfee5f8aded52d7b6e65a58bb196038 450 Gene3D G3DSA:1.10.630.10 34 256 6.3E-5 T 28-03-2018 CU254_RS16535 abfee5f8aded52d7b6e65a58bb196038 450 PRINTS PR00465 E-class P450 group IV signature 316 332 6.5E-5 T 28-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS16535 abfee5f8aded52d7b6e65a58bb196038 450 PRINTS PR00465 E-class P450 group IV signature 399 417 6.5E-5 T 28-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS16535 abfee5f8aded52d7b6e65a58bb196038 450 PRINTS PR00465 E-class P450 group IV signature 361 379 6.5E-5 T 28-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS16535 abfee5f8aded52d7b6e65a58bb196038 450 SUPERFAMILY SSF48264 65 427 8.51E-38 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS16535 abfee5f8aded52d7b6e65a58bb196038 450 Gene3D G3DSA:1.10.630.10 268 448 1.2E-33 T 28-03-2018 CU254_RS10740 d46c3a413a33d2957b0212c151517a7d 378 Gene3D G3DSA:3.40.50.2300 158 363 5.2E-33 T 28-03-2018 CU254_RS10740 d46c3a413a33d2957b0212c151517a7d 378 Pfam PF13407 Periplasmic binding protein domain 55 314 2.9E-56 T 28-03-2018 IPR025997 Periplasmic binding protein CU254_RS10740 d46c3a413a33d2957b0212c151517a7d 378 SUPERFAMILY SSF53822 48 349 3.53E-56 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CU254_RS10740 d46c3a413a33d2957b0212c151517a7d 378 Gene3D G3DSA:3.40.50.2300 49 157 8.4E-17 T 28-03-2018 CU254_RS00500 4f9d72e22909156426ee9e8c86c0b4ff 302 SUPERFAMILY SSF47413 13 69 3.75E-10 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS00500 4f9d72e22909156426ee9e8c86c0b4ff 302 Pfam PF12844 Helix-turn-helix domain 15 70 8.1E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS00500 4f9d72e22909156426ee9e8c86c0b4ff 302 SMART SM00530 17 72 3.4E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS00500 4f9d72e22909156426ee9e8c86c0b4ff 302 Gene3D G3DSA:1.10.260.40 3 80 2.9E-13 T 28-03-2018 CU254_RS34145 df1bd7763500c690f9b1122103273579 199 Gene3D G3DSA:3.40.50.10420 4 196 4.4E-51 T 28-03-2018 CU254_RS34145 df1bd7763500c690f9b1122103273579 199 PIRSF PIRSF006806 7 188 9.6E-35 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase CU254_RS34145 df1bd7763500c690f9b1122103273579 199 SUPERFAMILY SSF100950 10 192 1.49E-40 T 28-03-2018 CU254_RS34145 df1bd7763500c690f9b1122103273579 199 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 11 186 5.4E-33 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase CU254_RS34145 df1bd7763500c690f9b1122103273579 199 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 11 186 6.3E-37 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase CU254_RS22690 0e9fbf04a8f73b1c4f5f16e3cc51fd43 228 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 24 219 5.1E-43 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CU254_RS22690 0e9fbf04a8f73b1c4f5f16e3cc51fd43 228 Gene3D G3DSA:3.40.50.1240 21 226 1.6E-45 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CU254_RS22690 0e9fbf04a8f73b1c4f5f16e3cc51fd43 228 SUPERFAMILY SSF53254 22 224 1.16E-44 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CU254_RS22690 0e9fbf04a8f73b1c4f5f16e3cc51fd43 228 SMART SM00855 23 181 1.2E-9 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CU254_RS22690 0e9fbf04a8f73b1c4f5f16e3cc51fd43 228 PIRSF PIRSF000709 20 126 0.006 T 28-03-2018 CU254_RS15135 cb8335c6843b5c9444dcd781a5f9dd9f 524 Pfam PF00171 Aldehyde dehydrogenase family 37 487 6.3E-134 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CU254_RS15135 cb8335c6843b5c9444dcd781a5f9dd9f 524 ProDom PD003056 NUCLEOPROTEIN VIRAL NUCLEOCAPSID N RNA-BINDING CAPSID NSS NP WATERMELON GENE 81 147 3.0E-4 T 28-03-2018 IPR002517 Tospovirus nucleocapsid protein GO:0019013 CU254_RS15135 cb8335c6843b5c9444dcd781a5f9dd9f 524 Gene3D G3DSA:3.40.605.10 21 276 6.4E-73 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CU254_RS15135 cb8335c6843b5c9444dcd781a5f9dd9f 524 SUPERFAMILY SSF53720 27 487 1.26E-136 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CU254_RS15135 cb8335c6843b5c9444dcd781a5f9dd9f 524 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 260 267 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CU254_RS15135 cb8335c6843b5c9444dcd781a5f9dd9f 524 Gene3D G3DSA:3.40.309.10 277 473 7.6E-63 T 28-03-2018 CU254_RS09395 84405387be669ca65cf604cb6179dea2 502 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 489 6.4E-184 T 28-03-2018 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 CU254_RS09395 84405387be669ca65cf604cb6179dea2 502 SUPERFAMILY SSF51971 383 478 3.77E-10 T 28-03-2018 CU254_RS09395 84405387be669ca65cf604cb6179dea2 502 Gene3D G3DSA:3.50.50.60 421 497 8.1E-7 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS09395 84405387be669ca65cf604cb6179dea2 502 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 155 471 2.8E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS09395 84405387be669ca65cf604cb6179dea2 502 SUPERFAMILY SSF51971 153 416 7.46E-64 T 28-03-2018 CU254_RS09395 84405387be669ca65cf604cb6179dea2 502 Gene3D G3DSA:3.50.50.60 247 333 5.5E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS09395 84405387be669ca65cf604cb6179dea2 502 Gene3D G3DSA:3.50.50.60 334 416 2.1E-7 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS09395 84405387be669ca65cf604cb6179dea2 502 SUPERFAMILY SSF46548 5 164 2.72E-30 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CU254_RS09395 84405387be669ca65cf604cb6179dea2 502 Gene3D G3DSA:1.10.1060.10 6 148 1.3E-35 T 28-03-2018 CU254_RS09395 84405387be669ca65cf604cb6179dea2 502 Gene3D G3DSA:3.40.50.720 149 246 4.2E-23 T 28-03-2018 CU254_RS09395 84405387be669ca65cf604cb6179dea2 502 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 33 139 3.2E-18 T 28-03-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 CU254_RS09395 84405387be669ca65cf604cb6179dea2 502 PRINTS PR00419 Adrenodoxin reductase family signature 178 191 3.4E-22 T 28-03-2018 CU254_RS09395 84405387be669ca65cf604cb6179dea2 502 PRINTS PR00419 Adrenodoxin reductase family signature 155 177 3.4E-22 T 28-03-2018 CU254_RS09395 84405387be669ca65cf604cb6179dea2 502 PRINTS PR00419 Adrenodoxin reductase family signature 294 308 3.4E-22 T 28-03-2018 CU254_RS09395 84405387be669ca65cf604cb6179dea2 502 PRINTS PR00419 Adrenodoxin reductase family signature 220 230 3.4E-22 T 28-03-2018 CU254_RS25670 1fa4f45f410dace7e02809527f415671 192 Pfam PF16859 Bacterial transcriptional repressor C-terminal 74 180 2.6E-19 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS25670 1fa4f45f410dace7e02809527f415671 192 Gene3D G3DSA:1.10.357.10 64 190 9.3E-10 T 28-03-2018 CU254_RS25670 1fa4f45f410dace7e02809527f415671 192 Gene3D G3DSA:1.10.10.60 1 63 1.2E-15 T 28-03-2018 CU254_RS25670 1fa4f45f410dace7e02809527f415671 192 SUPERFAMILY SSF46689 16 67 1.7E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS25670 1fa4f45f410dace7e02809527f415671 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 64 1.0E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS25670 1fa4f45f410dace7e02809527f415671 192 SUPERFAMILY SSF48498 75 178 2.55E-11 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS25670 1fa4f45f410dace7e02809527f415671 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 3.9E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS25670 1fa4f45f410dace7e02809527f415671 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 3.9E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS25670 1fa4f45f410dace7e02809527f415671 192 ProSitePatterns PS01081 TetR-type HTH domain signature. 30 61 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CU254_RS08770 1b939ffaa933738f8076b983b6f1e6a2 457 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 337 444 1.1E-25 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CU254_RS08770 1b939ffaa933738f8076b983b6f1e6a2 457 PIRSF PIRSF000350 2 439 1.5E-73 T 28-03-2018 CU254_RS08770 1b939ffaa933738f8076b983b6f1e6a2 457 SUPERFAMILY SSF55424 333 455 5.15E-30 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CU254_RS08770 1b939ffaa933738f8076b983b6f1e6a2 457 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 317 1.1E-72 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS08770 1b939ffaa933738f8076b983b6f1e6a2 457 Gene3D G3DSA:3.30.390.30 329 451 3.5E-31 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CU254_RS08770 1b939ffaa933738f8076b983b6f1e6a2 457 Gene3D G3DSA:3.50.50.60 1 158 3.2E-32 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS08770 1b939ffaa933738f8076b983b6f1e6a2 457 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 54 1.2E-69 T 28-03-2018 CU254_RS08770 1b939ffaa933738f8076b983b6f1e6a2 457 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 255 269 1.2E-69 T 28-03-2018 CU254_RS08770 1b939ffaa933738f8076b983b6f1e6a2 457 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 135 144 1.2E-69 T 28-03-2018 CU254_RS08770 1b939ffaa933738f8076b983b6f1e6a2 457 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 419 439 1.2E-69 T 28-03-2018 CU254_RS08770 1b939ffaa933738f8076b983b6f1e6a2 457 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 297 304 1.2E-69 T 28-03-2018 CU254_RS08770 1b939ffaa933738f8076b983b6f1e6a2 457 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 397 412 1.2E-69 T 28-03-2018 CU254_RS08770 1b939ffaa933738f8076b983b6f1e6a2 457 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 333 354 1.2E-69 T 28-03-2018 CU254_RS08770 1b939ffaa933738f8076b983b6f1e6a2 457 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 170 195 1.2E-69 T 28-03-2018 CU254_RS08770 1b939ffaa933738f8076b983b6f1e6a2 457 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 1.2E-69 T 28-03-2018 CU254_RS08770 1b939ffaa933738f8076b983b6f1e6a2 457 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 6 455 5.8E-141 T 28-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 CU254_RS08770 1b939ffaa933738f8076b983b6f1e6a2 457 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 40 50 - T 28-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CU254_RS08770 1b939ffaa933738f8076b983b6f1e6a2 457 SUPERFAMILY SSF51905 3 326 1.3E-62 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS08770 1b939ffaa933738f8076b983b6f1e6a2 457 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 282 304 8.4E-39 T 28-03-2018 CU254_RS08770 1b939ffaa933738f8076b983b6f1e6a2 457 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 254 270 8.4E-39 T 28-03-2018 CU254_RS08770 1b939ffaa933738f8076b983b6f1e6a2 457 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 170 188 8.4E-39 T 28-03-2018 CU254_RS08770 1b939ffaa933738f8076b983b6f1e6a2 457 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 132 150 8.4E-39 T 28-03-2018 CU254_RS08770 1b939ffaa933738f8076b983b6f1e6a2 457 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 8.4E-39 T 28-03-2018 CU254_RS08770 1b939ffaa933738f8076b983b6f1e6a2 457 Gene3D G3DSA:3.40.50.720 159 328 2.1E-41 T 28-03-2018 CU254_RS39795 c4cb0b4c9725331293ddb950a107d1f7 226 SUPERFAMILY SSF53335 39 213 3.95E-38 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS39795 c4cb0b4c9725331293ddb950a107d1f7 226 Pfam PF08241 Methyltransferase domain 56 151 1.4E-24 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CU254_RS39795 c4cb0b4c9725331293ddb950a107d1f7 226 Gene3D G3DSA:3.40.50.150 10 222 4.2E-34 T 28-03-2018 CU254_RS16355 76792394b7e5724877504ada9f5adc54 262 Gene3D G3DSA:1.10.10.10 2 75 1.8E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS16355 76792394b7e5724877504ada9f5adc54 262 SUPERFAMILY SSF46785 5 66 6.28E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS16355 76792394b7e5724877504ada9f5adc54 262 Pfam PF08220 DeoR-like helix-turn-helix domain 6 58 1.2E-16 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CU254_RS16355 76792394b7e5724877504ada9f5adc54 262 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 1.2E-8 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CU254_RS16355 76792394b7e5724877504ada9f5adc54 262 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 1.2E-8 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CU254_RS16355 76792394b7e5724877504ada9f5adc54 262 Gene3D G3DSA:3.40.50.1360 76 248 2.8E-40 T 28-03-2018 CU254_RS16355 76792394b7e5724877504ada9f5adc54 262 SMART SM00420 6 58 3.8E-18 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CU254_RS16355 76792394b7e5724877504ada9f5adc54 262 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CU254_RS16355 76792394b7e5724877504ada9f5adc54 262 Pfam PF00455 DeoR C terminal sensor domain 74 240 1.3E-46 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain CU254_RS16355 76792394b7e5724877504ada9f5adc54 262 SMART SM01134 72 242 8.4E-59 T 28-03-2018 CU254_RS16355 76792394b7e5724877504ada9f5adc54 262 SUPERFAMILY SSF100950 74 243 6.28E-31 T 28-03-2018 CU254_RS10155 be02eb8980d70e4c848319d289625950 474 Gene3D G3DSA:2.40.33.10 76 159 6.5E-28 T 28-03-2018 CU254_RS10155 be02eb8980d70e4c848319d289625950 474 Pfam PF00224 Pyruvate kinase, barrel domain 3 336 4.7E-121 T 28-03-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CU254_RS10155 be02eb8980d70e4c848319d289625950 474 PRINTS PR01050 Pyruvate kinase family signature 293 311 1.1E-66 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CU254_RS10155 be02eb8980d70e4c848319d289625950 474 PRINTS PR01050 Pyruvate kinase family signature 243 267 1.1E-66 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CU254_RS10155 be02eb8980d70e4c848319d289625950 474 PRINTS PR01050 Pyruvate kinase family signature 312 328 1.1E-66 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CU254_RS10155 be02eb8980d70e4c848319d289625950 474 PRINTS PR01050 Pyruvate kinase family signature 216 242 1.1E-66 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CU254_RS10155 be02eb8980d70e4c848319d289625950 474 PRINTS PR01050 Pyruvate kinase family signature 185 199 1.1E-66 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CU254_RS10155 be02eb8980d70e4c848319d289625950 474 PRINTS PR01050 Pyruvate kinase family signature 60 76 1.1E-66 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CU254_RS10155 be02eb8980d70e4c848319d289625950 474 PRINTS PR01050 Pyruvate kinase family signature 268 292 1.1E-66 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CU254_RS10155 be02eb8980d70e4c848319d289625950 474 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 3 467 2.1E-170 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CU254_RS10155 be02eb8980d70e4c848319d289625950 474 Gene3D G3DSA:3.20.20.60 160 320 6.6E-63 T 28-03-2018 CU254_RS10155 be02eb8980d70e4c848319d289625950 474 Pfam PF02887 Pyruvate kinase, alpha/beta domain 355 466 9.6E-25 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CU254_RS10155 be02eb8980d70e4c848319d289625950 474 Gene3D G3DSA:3.40.1380.20 321 469 6.7E-41 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CU254_RS10155 be02eb8980d70e4c848319d289625950 474 Gene3D G3DSA:3.20.20.60 1 75 2.2E-16 T 28-03-2018 CU254_RS10155 be02eb8980d70e4c848319d289625950 474 ProSitePatterns PS00110 Pyruvate kinase active site signature. 214 226 - T 28-03-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CU254_RS10155 be02eb8980d70e4c848319d289625950 474 SUPERFAMILY SSF52935 322 468 2.09E-35 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CU254_RS10155 be02eb8980d70e4c848319d289625950 474 SUPERFAMILY SSF51621 2 76 1.01E-97 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CU254_RS10155 be02eb8980d70e4c848319d289625950 474 SUPERFAMILY SSF51621 166 336 1.01E-97 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CU254_RS10155 be02eb8980d70e4c848319d289625950 474 SUPERFAMILY SSF50800 71 165 1.92E-26 T 28-03-2018 IPR011037 Pyruvate kinase-like, insert domain CU254_RS36770 692dc57c3663c4dd729da69b2e4474b6 385 SUPERFAMILY SSF53756 1 378 8.98E-71 T 28-03-2018 CU254_RS36770 692dc57c3663c4dd729da69b2e4474b6 385 Gene3D G3DSA:3.40.50.2000 1 198 1.5E-29 T 28-03-2018 CU254_RS36770 692dc57c3663c4dd729da69b2e4474b6 385 Gene3D G3DSA:3.40.50.2000 204 366 1.8E-37 T 28-03-2018 CU254_RS36770 692dc57c3663c4dd729da69b2e4474b6 385 ProSitePatterns PS00375 UDP-glycosyltransferases signature. 277 318 - T 28-03-2018 IPR035595 UDP-glycosyltransferase family, conserved site Reactome: R-HSA-156588 CU254_RS36770 692dc57c3663c4dd729da69b2e4474b6 385 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 223 362 9.9E-15 T 28-03-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 Reactome: R-HSA-156588 CU254_RS01120 d8c4ba86a8eee562dd0a4ed4ca774b12 232 Pfam PF08281 Sigma-70, region 4 171 223 3.2E-14 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS01120 d8c4ba86a8eee562dd0a4ed4ca774b12 232 SUPERFAMILY SSF88946 44 144 3.22E-26 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS01120 d8c4ba86a8eee562dd0a4ed4ca774b12 232 Gene3D G3DSA:1.10.1740.10 40 135 4.3E-24 T 28-03-2018 CU254_RS01120 d8c4ba86a8eee562dd0a4ed4ca774b12 232 Pfam PF04542 Sigma-70 region 2 64 131 1.2E-14 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS01120 d8c4ba86a8eee562dd0a4ed4ca774b12 232 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 60 226 8.3E-28 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS01120 d8c4ba86a8eee562dd0a4ed4ca774b12 232 Gene3D G3DSA:1.10.10.10 136 230 4.8E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS01120 d8c4ba86a8eee562dd0a4ed4ca774b12 232 SUPERFAMILY SSF88659 165 227 1.46E-14 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS35960 717408b5f0c5a060d2c14b05813522d7 453 TIGRFAM TIGR00416 sms: DNA repair protein RadA 3 446 6.7E-157 T 28-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 CU254_RS35960 717408b5f0c5a060d2c14b05813522d7 453 SUPERFAMILY SSF54211 252 266 1.59E-31 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CU254_RS35960 717408b5f0c5a060d2c14b05813522d7 453 SUPERFAMILY SSF54211 300 449 1.59E-31 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CU254_RS35960 717408b5f0c5a060d2c14b05813522d7 453 Gene3D G3DSA:3.30.230.10 281 450 2.2E-21 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CU254_RS35960 717408b5f0c5a060d2c14b05813522d7 453 SMART SM00382 87 241 2.6E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS35960 717408b5f0c5a060d2c14b05813522d7 453 Pfam PF13481 AAA domain 56 219 4.7E-16 T 28-03-2018 CU254_RS35960 717408b5f0c5a060d2c14b05813522d7 453 PRINTS PR01874 DNA repair protein radA signature 319 342 2.7E-84 T 28-03-2018 CU254_RS35960 717408b5f0c5a060d2c14b05813522d7 453 PRINTS PR01874 DNA repair protein radA signature 245 271 2.7E-84 T 28-03-2018 CU254_RS35960 717408b5f0c5a060d2c14b05813522d7 453 PRINTS PR01874 DNA repair protein radA signature 121 138 2.7E-84 T 28-03-2018 CU254_RS35960 717408b5f0c5a060d2c14b05813522d7 453 PRINTS PR01874 DNA repair protein radA signature 210 238 2.7E-84 T 28-03-2018 CU254_RS35960 717408b5f0c5a060d2c14b05813522d7 453 PRINTS PR01874 DNA repair protein radA signature 11 35 2.7E-84 T 28-03-2018 CU254_RS35960 717408b5f0c5a060d2c14b05813522d7 453 PRINTS PR01874 DNA repair protein radA signature 79 107 2.7E-84 T 28-03-2018 CU254_RS35960 717408b5f0c5a060d2c14b05813522d7 453 PRINTS PR01874 DNA repair protein radA signature 171 195 2.7E-84 T 28-03-2018 CU254_RS35960 717408b5f0c5a060d2c14b05813522d7 453 SUPERFAMILY SSF52540 71 290 2.63E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS35960 717408b5f0c5a060d2c14b05813522d7 453 Gene3D G3DSA:3.40.50.300 71 278 7.2E-41 T 28-03-2018 CU254_RS35960 717408b5f0c5a060d2c14b05813522d7 453 Hamap MF_01498 DNA repair protein RadA [radA]. 22 450 42.355 T 28-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 CU254_RS29410 84ac39b71f305459572ffe9fcc8a17f0 260 Pfam PF13427 Domain of unknown function (DUF4111) 177 237 5.6E-5 T 28-03-2018 IPR025184 Domain of unknown function DUF4111 CU254_RS29410 84ac39b71f305459572ffe9fcc8a17f0 260 Gene3D G3DSA:3.30.460.10 3 230 2.5E-4 T 28-03-2018 CU254_RS08835 9500ee44b5fac88a93ff2a7a782ddd29 125 SUPERFAMILY SSF89360 21 115 6.47E-27 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CU254_RS08835 9500ee44b5fac88a93ff2a7a782ddd29 125 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 107 124 - T 28-03-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 CU254_RS08835 9500ee44b5fac88a93ff2a7a782ddd29 125 Pfam PF01521 Iron-sulphur cluster biosynthesis 21 122 3.5E-18 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CU254_RS08835 9500ee44b5fac88a93ff2a7a782ddd29 125 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 21 125 2.0E-34 T 28-03-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 CU254_RS08835 9500ee44b5fac88a93ff2a7a782ddd29 125 Gene3D G3DSA:2.60.300.12 21 125 3.6E-31 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CU254_RS24390 7943a4ef58744771036f8329011617fb 320 Pfam PF02541 Ppx/GppA phosphatase family 36 305 2.7E-49 T 28-03-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 CU254_RS24390 7943a4ef58744771036f8329011617fb 320 Gene3D G3DSA:3.30.420.150 130 311 1.8E-30 T 28-03-2018 CU254_RS24390 7943a4ef58744771036f8329011617fb 320 Gene3D G3DSA:3.30.420.40 3 129 5.5E-26 T 28-03-2018 CU254_RS24390 7943a4ef58744771036f8329011617fb 320 SUPERFAMILY SSF53067 134 307 1.26E-24 T 28-03-2018 CU254_RS24390 7943a4ef58744771036f8329011617fb 320 SUPERFAMILY SSF53067 9 129 3.63E-23 T 28-03-2018 CU254_RS21375 48362f0109d9c74986d5ca8ad41aff8b 582 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 3 173 1.4E-40 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CU254_RS21375 48362f0109d9c74986d5ca8ad41aff8b 582 SUPERFAMILY SSF52467 185 347 2.5E-40 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CU254_RS21375 48362f0109d9c74986d5ca8ad41aff8b 582 SUPERFAMILY SSF52518 2 173 1.4E-40 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS21375 48362f0109d9c74986d5ca8ad41aff8b 582 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 385 531 1.0E-35 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CU254_RS21375 48362f0109d9c74986d5ca8ad41aff8b 582 SUPERFAMILY SSF52518 362 557 2.14E-54 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS21375 48362f0109d9c74986d5ca8ad41aff8b 582 Gene3D G3DSA:3.40.50.970 1 190 3.9E-41 T 28-03-2018 CU254_RS21375 48362f0109d9c74986d5ca8ad41aff8b 582 Gene3D G3DSA:3.40.50.1220 191 334 4.6E-33 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CU254_RS21375 48362f0109d9c74986d5ca8ad41aff8b 582 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 422 441 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CU254_RS21375 48362f0109d9c74986d5ca8ad41aff8b 582 Gene3D G3DSA:3.40.50.970 335 539 4.5E-38 T 28-03-2018 CU254_RS21375 48362f0109d9c74986d5ca8ad41aff8b 582 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 195 321 3.6E-29 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CU254_RS08215 fad1dfff4df46f1f22c539cf15aacf86 135 Pfam PF04237 YjbR 14 116 1.7E-8 T 28-03-2018 IPR007351 Uncharacterised protein YjbR CU254_RS05040 14af986cdb1af480195288978ba53bca 1264 SUPERFAMILY SSF56719 520 940 1.31E-132 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CU254_RS05040 14af986cdb1af480195288978ba53bca 1264 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 1122 1157 0.38 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CU254_RS05040 14af986cdb1af480195288978ba53bca 1264 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 1186 1206 0.023 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CU254_RS05040 14af986cdb1af480195288978ba53bca 1264 SUPERFAMILY SSF56719 24 89 4.19E-21 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CU254_RS05040 14af986cdb1af480195288978ba53bca 1264 SUPERFAMILY SSF51294 89 205 5.63E-23 T 28-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CU254_RS05040 14af986cdb1af480195288978ba53bca 1264 SUPERFAMILY SSF51294 468 523 5.63E-23 T 28-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CU254_RS05040 14af986cdb1af480195288978ba53bca 1264 PRINTS PR00379 Intein signature 194 206 5.2E-11 T 28-03-2018 IPR006142 Intein GO:0016539 CU254_RS05040 14af986cdb1af480195288978ba53bca 1264 PRINTS PR00379 Intein signature 518 527 5.2E-11 T 28-03-2018 IPR006142 Intein GO:0016539 CU254_RS05040 14af986cdb1af480195288978ba53bca 1264 PRINTS PR00379 Intein signature 294 306 5.2E-11 T 28-03-2018 IPR006142 Intein GO:0016539 CU254_RS05040 14af986cdb1af480195288978ba53bca 1264 PRINTS PR00379 Intein signature 143 156 5.2E-11 T 28-03-2018 IPR006142 Intein GO:0016539 CU254_RS05040 14af986cdb1af480195288978ba53bca 1264 PRINTS PR00379 Intein signature 322 337 5.2E-11 T 28-03-2018 IPR006142 Intein GO:0016539 CU254_RS05040 14af986cdb1af480195288978ba53bca 1264 PRINTS PR00379 Intein signature 499 516 5.2E-11 T 28-03-2018 IPR006142 Intein GO:0016539 CU254_RS05040 14af986cdb1af480195288978ba53bca 1264 Gene3D G3DSA:3.10.28.10 194 258 0.37 T 28-03-2018 IPR027434 Homing endonuclease GO:0004519 CU254_RS05040 14af986cdb1af480195288978ba53bca 1264 Gene3D G3DSA:3.90.199.10 50 90 2.7E-12 T 28-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 CU254_RS05040 14af986cdb1af480195288978ba53bca 1264 Gene3D G3DSA:2.120.10.90 959 1225 1.2E-47 T 28-03-2018 CU254_RS05040 14af986cdb1af480195288978ba53bca 1264 Gene3D G3DSA:3.30.1360.40 686 786 1.6E-24 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CU254_RS05040 14af986cdb1af480195288978ba53bca 1264 Pfam PF13403 Hint domain 89 128 1.6E-6 T 28-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CU254_RS05040 14af986cdb1af480195288978ba53bca 1264 Gene3D G3DSA:2.170.16.10 91 193 3.6E-16 T 28-03-2018 CU254_RS05040 14af986cdb1af480195288978ba53bca 1264 SMART SM00434 495 918 1.8E-175 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CU254_RS05040 14af986cdb1af480195288978ba53bca 1264 SUPERFAMILY SSF55608 281 365 2.1E-10 T 28-03-2018 IPR027434 Homing endonuclease GO:0004519 CU254_RS05040 14af986cdb1af480195288978ba53bca 1264 Gene3D G3DSA:3.10.28.10 291 392 2.4E-11 T 28-03-2018 IPR027434 Homing endonuclease GO:0004519 CU254_RS05040 14af986cdb1af480195288978ba53bca 1264 SUPERFAMILY SSF101904 960 1224 1.57E-40 T 28-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal CU254_RS05040 14af986cdb1af480195288978ba53bca 1264 Gene3D G3DSA:1.10.268.10 798 940 1.2E-44 T 28-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CU254_RS05040 14af986cdb1af480195288978ba53bca 1264 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 48 89 3.6E-12 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CU254_RS05040 14af986cdb1af480195288978ba53bca 1264 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 520 923 1.6E-121 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CU254_RS05040 14af986cdb1af480195288978ba53bca 1264 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 502 524 3.1E-4 T 28-03-2018 IPR030934 Intein C-terminal splicing region CU254_RS05040 14af986cdb1af480195288978ba53bca 1264 Gene3D G3DSA:3.90.199.10 515 664 3.8E-56 T 28-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 CU254_RS05040 14af986cdb1af480195288978ba53bca 1264 SMART SM00305 483 529 7.6E-7 T 28-03-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CU254_RS05040 14af986cdb1af480195288978ba53bca 1264 Pfam PF14528 LAGLIDADG-like domain 295 365 2.4E-9 T 28-03-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 CU254_RS05040 14af986cdb1af480195288978ba53bca 1264 Gene3D G3DSA:2.170.16.10 426 514 1.1E-7 T 28-03-2018 CU254_RS09780 0a2cf2f15b90c3e484fa60a71a946843 127 SUPERFAMILY SSF55331 2 126 1.12E-36 T 28-03-2018 IPR014347 Tautomerase/MIF superfamily CU254_RS09780 0a2cf2f15b90c3e484fa60a71a946843 127 Pfam PF14552 Tautomerase enzyme 38 119 8.4E-30 T 28-03-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 CU254_RS09780 0a2cf2f15b90c3e484fa60a71a946843 127 Gene3D G3DSA:3.30.429.10 1 127 1.0E-29 T 28-03-2018 CU254_RS31495 97e821ae70a92c8cbe19e2ef430a1dad 411 Gene3D G3DSA:2.30.40.10 1 69 1.3E-20 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS31495 97e821ae70a92c8cbe19e2ef430a1dad 411 Gene3D G3DSA:3.20.20.140 70 313 2.3E-42 T 28-03-2018 CU254_RS31495 97e821ae70a92c8cbe19e2ef430a1dad 411 SUPERFAMILY SSF51338 1 55 1.04E-28 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS31495 97e821ae70a92c8cbe19e2ef430a1dad 411 SUPERFAMILY SSF51338 328 402 1.04E-28 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS31495 97e821ae70a92c8cbe19e2ef430a1dad 411 Pfam PF01979 Amidohydrolase family 52 377 1.1E-32 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CU254_RS31495 97e821ae70a92c8cbe19e2ef430a1dad 411 Gene3D G3DSA:2.30.40.10 314 407 1.1E-15 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS31495 97e821ae70a92c8cbe19e2ef430a1dad 411 SUPERFAMILY SSF51556 55 329 3.28E-58 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS22815 03ee221e8b4a4ed4a44042f6b5f38d60 208 Gene3D G3DSA:3.40.50.2300 2 127 5.8E-36 T 28-03-2018 CU254_RS22815 03ee221e8b4a4ed4a44042f6b5f38d60 208 SMART SM00448 3 116 2.2E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS22815 03ee221e8b4a4ed4a44042f6b5f38d60 208 Pfam PF00196 Bacterial regulatory proteins, luxR family 145 200 2.7E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS22815 03ee221e8b4a4ed4a44042f6b5f38d60 208 Pfam PF00072 Response regulator receiver domain 6 116 9.3E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS22815 03ee221e8b4a4ed4a44042f6b5f38d60 208 SUPERFAMILY SSF52172 2 134 4.55E-33 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS22815 03ee221e8b4a4ed4a44042f6b5f38d60 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 188 2.7E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS22815 03ee221e8b4a4ed4a44042f6b5f38d60 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 146 160 2.7E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS22815 03ee221e8b4a4ed4a44042f6b5f38d60 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 176 2.7E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS22815 03ee221e8b4a4ed4a44042f6b5f38d60 208 SMART SM00421 143 200 1.2E-23 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS22815 03ee221e8b4a4ed4a44042f6b5f38d60 208 Gene3D G3DSA:1.10.10.10 128 208 4.9E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS22815 03ee221e8b4a4ed4a44042f6b5f38d60 208 SUPERFAMILY SSF46894 135 206 1.19E-21 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS32650 eee3d0a210168fc051dda977d4182dc5 567 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 92 418 5.9E-33 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CU254_RS32650 eee3d0a210168fc051dda977d4182dc5 567 SUPERFAMILY SSF53850 37 559 1.45E-53 T 28-03-2018 CU254_RS32650 eee3d0a210168fc051dda977d4182dc5 567 Gene3D G3DSA:3.40.190.10 165 300 8.3E-21 T 28-03-2018 CU254_RS32650 eee3d0a210168fc051dda977d4182dc5 567 Gene3D G3DSA:3.90.76.10 63 164 1.8E-12 T 28-03-2018 CU254_RS32650 eee3d0a210168fc051dda977d4182dc5 567 Gene3D G3DSA:3.10.105.10 301 534 7.6E-29 T 28-03-2018 CU254_RS26000 7a262cf6bdf84e4d3d844f0603babdc3 215 Gene3D G3DSA:1.10.10.60 15 49 2.5E-16 T 28-03-2018 CU254_RS26000 7a262cf6bdf84e4d3d844f0603babdc3 215 SUPERFAMILY SSF48498 95 207 1.99E-15 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS26000 7a262cf6bdf84e4d3d844f0603babdc3 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 28 73 1.5E-18 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS26000 7a262cf6bdf84e4d3d844f0603babdc3 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 41 1.3E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS26000 7a262cf6bdf84e4d3d844f0603babdc3 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 49 72 1.3E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS26000 7a262cf6bdf84e4d3d844f0603babdc3 215 Gene3D G3DSA:1.10.357.10 95 215 8.2E-16 T 28-03-2018 CU254_RS26000 7a262cf6bdf84e4d3d844f0603babdc3 215 SUPERFAMILY SSF46689 19 99 3.84E-19 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS26000 7a262cf6bdf84e4d3d844f0603babdc3 215 Gene3D G3DSA:1.10.260.40 50 94 1.6E-14 T 28-03-2018 CU254_RS28435 c752b75eb7a25d25c978a3dc77424893 364 Gene3D G3DSA:3.30.565.10 237 363 2.3E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS28435 c752b75eb7a25d25c978a3dc77424893 364 SUPERFAMILY SSF55874 261 358 2.38E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS28435 c752b75eb7a25d25c978a3dc77424893 364 Pfam PF07730 Histidine kinase 163 226 9.3E-15 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CU254_RS28275 b00f222dbf81ece329855d9e62745b85 292 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 3 166 6.6E-47 T 28-03-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 CU254_RS28275 b00f222dbf81ece329855d9e62745b85 292 Gene3D G3DSA:3.30.465.10 52 167 2.8E-33 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CU254_RS28275 b00f222dbf81ece329855d9e62745b85 292 SMART SM01092 171 279 4.0E-18 T 28-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal CU254_RS28275 b00f222dbf81ece329855d9e62745b85 292 SUPERFAMILY SSF56176 2 166 6.54E-50 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CU254_RS28275 b00f222dbf81ece329855d9e62745b85 292 Gene3D G3DSA:3.30.390.50 170 288 5.5E-28 T 28-03-2018 CU254_RS28275 b00f222dbf81ece329855d9e62745b85 292 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 172 278 1.8E-9 T 28-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal CU254_RS28275 b00f222dbf81ece329855d9e62745b85 292 SUPERFAMILY SSF55447 172 284 1.19E-18 T 28-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal CU254_RS28275 b00f222dbf81ece329855d9e62745b85 292 Gene3D G3DSA:3.30.43.10 5 51 2.0E-17 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CU254_RS28480 db9d43cfb6e2d60c665b7b12e2af0966 391 Gene3D G3DSA:3.20.20.80 44 293 9.1E-9 T 28-03-2018 CU254_RS28480 db9d43cfb6e2d60c665b7b12e2af0966 391 SUPERFAMILY SSF51445 59 255 4.66E-10 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS20495 810f58ef697b3d26407994a3c00b3830 296 PIRSF PIRSF020623 16 296 9.2E-72 T 28-03-2018 IPR011965 Phenylacetic acid degradation operon negative regulatory protein PaaX GO:0006351 CU254_RS20495 810f58ef697b3d26407994a3c00b3830 296 Gene3D G3DSA:1.10.10.10 30 113 2.3E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS20495 810f58ef697b3d26407994a3c00b3830 296 Pfam PF08223 PaaX-like protein C-terminal domain 198 287 2.5E-23 T 28-03-2018 IPR013225 PaaX-like, C-terminal CU254_RS20495 810f58ef697b3d26407994a3c00b3830 296 Pfam PF07848 PaaX-like protein 31 97 4.3E-15 T 28-03-2018 IPR012906 PaaX-like, N-terminal CU254_RS13675 c925577f6c4ac9ed0d197467d6e0a0a3 1135 Pfam PF05922 Peptidase inhibitor I9 44 126 1.3E-6 T 28-03-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 CU254_RS13675 c925577f6c4ac9ed0d197467d6e0a0a3 1135 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 448 458 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CU254_RS13675 c925577f6c4ac9ed0d197467d6e0a0a3 1135 Gene3D G3DSA:3.40.50.200 116 516 1.7E-48 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS13675 c925577f6c4ac9ed0d197467d6e0a0a3 1135 Gene3D G3DSA:2.60.40.10 524 759 9.4E-6 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS13675 c925577f6c4ac9ed0d197467d6e0a0a3 1135 Gene3D G3DSA:2.60.40.10 884 1114 7.0E-5 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS13675 c925577f6c4ac9ed0d197467d6e0a0a3 1135 Gene3D G3DSA:3.30.70.80 34 115 5.8E-11 T 28-03-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 CU254_RS13675 c925577f6c4ac9ed0d197467d6e0a0a3 1135 SUPERFAMILY SSF52743 182 513 8.38E-43 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS13675 c925577f6c4ac9ed0d197467d6e0a0a3 1135 PRINTS PR00723 Subtilisin serine protease family (S8) signature 447 463 3.4E-6 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CU254_RS13675 c925577f6c4ac9ed0d197467d6e0a0a3 1135 PRINTS PR00723 Subtilisin serine protease family (S8) signature 187 206 3.4E-6 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CU254_RS35295 de849c1678079c14274525b170172863 320 Gene3D G3DSA:3.40.190.10 30 136 1.5E-16 T 28-03-2018 CU254_RS35295 de849c1678079c14274525b170172863 320 SUPERFAMILY SSF53850 32 252 8.59E-41 T 28-03-2018 CU254_RS35295 de849c1678079c14274525b170172863 320 Gene3D G3DSA:3.40.190.10 137 320 1.6E-26 T 28-03-2018 CU254_RS35295 de849c1678079c14274525b170172863 320 Pfam PF09084 NMT1/THI5 like 44 252 7.3E-30 T 28-03-2018 IPR015168 SsuA/THI5-like CU254_RS00005 bab87e1c6f8787b64a4b76c5bf1e2393 249 Gene3D G3DSA:3.40.50.1110 30 233 2.4E-25 T 28-03-2018 CU254_RS00005 bab87e1c6f8787b64a4b76c5bf1e2393 249 SUPERFAMILY SSF52266 44 232 2.44E-27 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CU254_RS00005 bab87e1c6f8787b64a4b76c5bf1e2393 249 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 51 224 4.4E-19 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CU254_RS07400 21cb8b3ac5f5ea78da118875de54984a 425 SUPERFAMILY SSF53383 5 421 5.06E-170 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS07400 21cb8b3ac5f5ea78da118875de54984a 425 PIRSF PIRSF000412 2 419 3.5E-156 T 28-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CU254_RS07400 21cb8b3ac5f5ea78da118875de54984a 425 Gene3D G3DSA:3.90.1150.10 275 420 1.6E-52 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS07400 21cb8b3ac5f5ea78da118875de54984a 425 Gene3D G3DSA:3.40.640.10 38 274 9.8E-56 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS07400 21cb8b3ac5f5ea78da118875de54984a 425 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 223 239 - T 28-03-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CU254_RS07400 21cb8b3ac5f5ea78da118875de54984a 425 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 8 421 50.348 T 28-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CU254_RS07400 21cb8b3ac5f5ea78da118875de54984a 425 Pfam PF00464 Serine hydroxymethyltransferase 9 390 1.6E-160 T 28-03-2018 CU254_RS27275 2c9986f8e78a04b6af542147f4fba583 274 Gene3D G3DSA:3.40.50.150 1 274 1.3E-43 T 28-03-2018 CU254_RS27275 2c9986f8e78a04b6af542147f4fba583 274 SUPERFAMILY SSF53335 2 254 2.9E-37 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS27275 2c9986f8e78a04b6af542147f4fba583 274 PIRSF PIRSF017393 1 274 9.3E-79 T 28-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CU254_RS27275 2c9986f8e78a04b6af542147f4fba583 274 Pfam PF04672 S-adenosyl methyltransferase 1 274 1.6E-78 T 28-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CU254_RS10855 37122120500b1cdb90df9e5e91faa630 253 SUPERFAMILY SSF53067 7 249 1.51E-31 T 28-03-2018 CU254_RS10855 37122120500b1cdb90df9e5e91faa630 253 Gene3D G3DSA:3.30.420.40 2 120 5.1E-21 T 28-03-2018 CU254_RS10855 37122120500b1cdb90df9e5e91faa630 253 Pfam PF00480 ROK family 8 166 8.7E-16 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CU254_RS10855 37122120500b1cdb90df9e5e91faa630 253 Gene3D G3DSA:3.30.420.40 121 252 4.9E-25 T 28-03-2018 CU254_RS27980 128d141a0762ba40b29f5ab9afaf72df 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 175 1.6E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS27980 128d141a0762ba40b29f5ab9afaf72df 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 1.6E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS27980 128d141a0762ba40b29f5ab9afaf72df 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 156 1.6E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS27980 128d141a0762ba40b29f5ab9afaf72df 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 70 81 1.6E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS27980 128d141a0762ba40b29f5ab9afaf72df 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 193 213 1.6E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS27980 128d141a0762ba40b29f5ab9afaf72df 235 SUPERFAMILY SSF51735 5 229 8.72E-68 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS27980 128d141a0762ba40b29f5ab9afaf72df 235 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 229 1.6E-56 T 28-03-2018 CU254_RS27980 128d141a0762ba40b29f5ab9afaf72df 235 Gene3D G3DSA:3.40.50.720 1 232 1.5E-61 T 28-03-2018 CU254_RS07640 7a9e7b4dfab1be919a83f137d7d7a415 314 Gene3D G3DSA:2.130.10.10 14 198 7.6E-6 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CU254_RS07640 7a9e7b4dfab1be919a83f137d7d7a415 314 SUPERFAMILY SSF82171 46 304 2.71E-16 T 28-03-2018 CU254_RS07640 7a9e7b4dfab1be919a83f137d7d7a415 314 Gene3D G3DSA:2.130.10.150 199 314 8.7E-9 T 28-03-2018 CU254_RS07640 7a9e7b4dfab1be919a83f137d7d7a415 314 Pfam PF07676 WD40-like Beta Propeller Repeat 123 140 0.088 T 28-03-2018 IPR011659 WD40-like Beta Propeller CU254_RS09545 b489454d78dbb4fe0c905ab224c86936 64 Pfam PF11248 Protein of unknown function (DUF3046) 1 62 2.9E-28 T 28-03-2018 IPR021408 Protein of unknown function DUF3046 CU254_RS17670 8a372710d3a7a861f3aef772c113ee85 442 Gene3D G3DSA:3.20.20.30 1 442 6.9E-90 T 28-03-2018 CU254_RS17670 8a372710d3a7a861f3aef772c113ee85 442 SUPERFAMILY SSF51679 6 442 9.68E-104 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS17670 8a372710d3a7a861f3aef772c113ee85 442 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 16 438 2.1E-118 T 28-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 CU254_RS17670 8a372710d3a7a861f3aef772c113ee85 442 Pfam PF00296 Luciferase-like monooxygenase 26 393 7.9E-50 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS17670 8a372710d3a7a861f3aef772c113ee85 442 PIRSF PIRSF000337 2 442 1.2E-140 T 28-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 CU254_RS04690 fe397de33d07647c2f755ec1a4c34246 178 Pfam PF01381 Helix-turn-helix 6 57 1.6E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS04690 fe397de33d07647c2f755ec1a4c34246 178 SMART SM00530 5 60 2.0E-15 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS04690 fe397de33d07647c2f755ec1a4c34246 178 Pfam PF07883 Cupin domain 105 171 4.3E-19 T 28-03-2018 IPR013096 Cupin 2, conserved barrel CU254_RS04690 fe397de33d07647c2f755ec1a4c34246 178 Gene3D G3DSA:2.60.120.10 71 178 1.0E-21 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS04690 fe397de33d07647c2f755ec1a4c34246 178 Gene3D G3DSA:1.10.260.40 2 70 3.4E-18 T 28-03-2018 CU254_RS04690 fe397de33d07647c2f755ec1a4c34246 178 SUPERFAMILY SSF47413 4 66 7.98E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS04690 fe397de33d07647c2f755ec1a4c34246 178 SUPERFAMILY SSF51182 45 177 6.68E-30 T 28-03-2018 IPR011051 RmlC-like cupin domain CU254_RS41725 f80dd98b35418c6c0e6612eadf689d24 554 Pfam PF00772 DnaB-like helicase N terminal domain 174 264 2.3E-6 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CU254_RS41725 f80dd98b35418c6c0e6612eadf689d24 554 Pfam PF00772 DnaB-like helicase N terminal domain 413 477 3.2E-5 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CU254_RS41725 f80dd98b35418c6c0e6612eadf689d24 554 SUPERFAMILY SSF48024 172 223 1.29E-6 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CU254_RS41725 f80dd98b35418c6c0e6612eadf689d24 554 Gene3D G3DSA:1.10.860.10 156 314 2.9E-18 T 28-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal CU254_RS41725 f80dd98b35418c6c0e6612eadf689d24 554 Gene3D G3DSA:1.10.860.10 385 530 1.7E-14 T 28-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal CU254_RS41725 f80dd98b35418c6c0e6612eadf689d24 554 SUPERFAMILY SSF48024 393 496 4.71E-5 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CU254_RS25290 a22aaec6da961cac468b1af3aadd4ec8 352 SUPERFAMILY SSF53187 270 349 1.04E-42 T 28-03-2018 CU254_RS25290 a22aaec6da961cac468b1af3aadd4ec8 352 SUPERFAMILY SSF53187 2 169 1.04E-42 T 28-03-2018 CU254_RS25290 a22aaec6da961cac468b1af3aadd4ec8 352 Pfam PF01546 Peptidase family M20/M25/M40 67 348 4.1E-25 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CU254_RS25290 a22aaec6da961cac468b1af3aadd4ec8 352 PRINTS PR00934 X-His dipeptidase (M25) signature 123 140 2.6E-5 T 28-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 CU254_RS25290 a22aaec6da961cac468b1af3aadd4ec8 352 PRINTS PR00934 X-His dipeptidase (M25) signature 229 248 2.6E-5 T 28-03-2018 IPR001160 Peptidase M20C, Xaa-His dipeptidase GO:0006508 CU254_RS25290 a22aaec6da961cac468b1af3aadd4ec8 352 SUPERFAMILY SSF55031 169 258 1.33E-18 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CU254_RS25290 a22aaec6da961cac468b1af3aadd4ec8 352 Pfam PF07687 Peptidase dimerisation domain 167 254 6.4E-17 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CU254_RS25290 a22aaec6da961cac468b1af3aadd4ec8 352 Gene3D G3DSA:3.40.630.10 1 172 5.7E-27 T 28-03-2018 CU254_RS25290 a22aaec6da961cac468b1af3aadd4ec8 352 Gene3D G3DSA:3.30.70.360 173 261 1.2E-20 T 28-03-2018 CU254_RS02885 18dee37eeddfdd70ab2bf0610d68d56e 193 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 2 86 7.7E-14 T 28-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal CU254_RS02885 18dee37eeddfdd70ab2bf0610d68d56e 193 SUPERFAMILY SSF51735 1 177 2.03E-28 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS02885 18dee37eeddfdd70ab2bf0610d68d56e 193 Gene3D G3DSA:3.40.50.720 1 162 4.4E-24 T 28-03-2018 CU254_RS34855 b9549d05857fe9368581470af79739d8 170 Gene3D G3DSA:3.40.630.30 7 166 7.0E-24 T 28-03-2018 CU254_RS34855 b9549d05857fe9368581470af79739d8 170 SUPERFAMILY SSF55729 13 160 2.62E-22 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS34855 b9549d05857fe9368581470af79739d8 170 Pfam PF13673 Acetyltransferase (GNAT) domain 52 149 2.8E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS12530 610938ea6ec8c530b054fdbad85bf33b 402 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 329 338 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CU254_RS12530 610938ea6ec8c530b054fdbad85bf33b 402 PRINTS PR00385 P450 superfamily signature 327 336 3.6E-5 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS12530 610938ea6ec8c530b054fdbad85bf33b 402 PRINTS PR00385 P450 superfamily signature 231 248 3.6E-5 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS12530 610938ea6ec8c530b054fdbad85bf33b 402 PRINTS PR00385 P450 superfamily signature 336 347 3.6E-5 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS12530 610938ea6ec8c530b054fdbad85bf33b 402 PRINTS PR00359 B-class P450 signature 306 321 1.2E-57 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS12530 610938ea6ec8c530b054fdbad85bf33b 402 PRINTS PR00359 B-class P450 signature 87 98 1.2E-57 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS12530 610938ea6ec8c530b054fdbad85bf33b 402 PRINTS PR00359 B-class P450 signature 336 347 1.2E-57 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS12530 610938ea6ec8c530b054fdbad85bf33b 402 PRINTS PR00359 B-class P450 signature 134 150 1.2E-57 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS12530 610938ea6ec8c530b054fdbad85bf33b 402 PRINTS PR00359 B-class P450 signature 151 166 1.2E-57 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS12530 610938ea6ec8c530b054fdbad85bf33b 402 PRINTS PR00359 B-class P450 signature 278 305 1.2E-57 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS12530 610938ea6ec8c530b054fdbad85bf33b 402 PRINTS PR00359 B-class P450 signature 260 271 1.2E-57 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS12530 610938ea6ec8c530b054fdbad85bf33b 402 PRINTS PR00359 B-class P450 signature 327 336 1.2E-57 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS12530 610938ea6ec8c530b054fdbad85bf33b 402 PRINTS PR00359 B-class P450 signature 188 210 1.2E-57 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS12530 610938ea6ec8c530b054fdbad85bf33b 402 Pfam PF00067 Cytochrome P450 262 353 2.4E-17 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS12530 610938ea6ec8c530b054fdbad85bf33b 402 Gene3D G3DSA:1.10.630.10 20 389 3.9E-63 T 28-03-2018 CU254_RS12530 610938ea6ec8c530b054fdbad85bf33b 402 SUPERFAMILY SSF48264 23 387 2.75E-84 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS20185 4d50f6ba0b95255963cff8f9f7bb6c75 285 Pfam PF03466 LysR substrate binding domain 90 284 4.3E-36 T 28-03-2018 IPR005119 LysR, substrate-binding CU254_RS20185 4d50f6ba0b95255963cff8f9f7bb6c75 285 SUPERFAMILY SSF46785 3 114 1.82E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS20185 4d50f6ba0b95255963cff8f9f7bb6c75 285 SUPERFAMILY SSF53850 90 284 7.9E-35 T 28-03-2018 CU254_RS20185 4d50f6ba0b95255963cff8f9f7bb6c75 285 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 2.7E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS20185 4d50f6ba0b95255963cff8f9f7bb6c75 285 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 2.7E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS20185 4d50f6ba0b95255963cff8f9f7bb6c75 285 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 2.7E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS20185 4d50f6ba0b95255963cff8f9f7bb6c75 285 Gene3D G3DSA:3.40.190.10 180 269 2.1E-19 T 28-03-2018 CU254_RS20185 4d50f6ba0b95255963cff8f9f7bb6c75 285 Gene3D G3DSA:1.10.10.10 2 89 4.9E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS20185 4d50f6ba0b95255963cff8f9f7bb6c75 285 Gene3D G3DSA:3.40.190.10 90 179 5.3E-26 T 28-03-2018 CU254_RS20185 4d50f6ba0b95255963cff8f9f7bb6c75 285 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 65 1.1E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS41255 daaf2b11e6b7418a9863796d4a82a11a 650 Gene3D G3DSA:3.40.50.300 11 157 7.0E-13 T 28-03-2018 CU254_RS41255 daaf2b11e6b7418a9863796d4a82a11a 650 Gene3D G3DSA:1.25.40.10 394 644 1.6E-19 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS41255 daaf2b11e6b7418a9863796d4a82a11a 650 SUPERFAMILY SSF52540 11 252 1.83E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS41255 daaf2b11e6b7418a9863796d4a82a11a 650 SMART SM00028 438 471 0.15 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS41255 daaf2b11e6b7418a9863796d4a82a11a 650 SMART SM00028 478 511 24.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS41255 daaf2b11e6b7418a9863796d4a82a11a 650 SMART SM00028 518 551 240.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS41255 daaf2b11e6b7418a9863796d4a82a11a 650 SUPERFAMILY SSF48452 436 581 1.18E-17 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS41255 daaf2b11e6b7418a9863796d4a82a11a 650 Pfam PF13424 Tetratricopeptide repeat 438 506 5.4E-9 T 28-03-2018 CU254_RS36140 851053e22d319cd9ba2ae972662baab4 317 SUPERFAMILY SSF47090 225 279 1.18E-10 T 28-03-2018 IPR002477 Peptidoglycan binding-like CU254_RS36140 851053e22d319cd9ba2ae972662baab4 317 SMART SM00644 48 197 7.9E-4 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CU254_RS36140 851053e22d319cd9ba2ae972662baab4 317 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 58 197 4.4E-14 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CU254_RS36140 851053e22d319cd9ba2ae972662baab4 317 SMART SM00701 36 191 5.1E-4 T 28-03-2018 IPR006619 Peptidoglycan recognition protein family domain, metazoa/bacteria GO:0008270|GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CU254_RS36140 851053e22d319cd9ba2ae972662baab4 317 Pfam PF01471 Putative peptidoglycan binding domain 236 278 8.8E-7 T 28-03-2018 IPR002477 Peptidoglycan binding-like CU254_RS36140 851053e22d319cd9ba2ae972662baab4 317 Gene3D G3DSA:1.10.101.10 223 284 2.6E-14 T 28-03-2018 IPR002477 Peptidoglycan binding-like CU254_RS36140 851053e22d319cd9ba2ae972662baab4 317 SUPERFAMILY SSF55846 36 212 3.14E-38 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CU254_RS36140 851053e22d319cd9ba2ae972662baab4 317 Gene3D G3DSA:3.40.80.10 25 216 9.6E-39 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CU254_RS14300 71e0f89ad378d33069b0dfc34ce859a4 567 PRINTS PR01165 Cytochrome c oxidase subunit I signature 322 343 1.4E-97 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CU254_RS14300 71e0f89ad378d33069b0dfc34ce859a4 567 PRINTS PR01165 Cytochrome c oxidase subunit I signature 357 375 1.4E-97 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CU254_RS14300 71e0f89ad378d33069b0dfc34ce859a4 567 PRINTS PR01165 Cytochrome c oxidase subunit I signature 233 254 1.4E-97 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CU254_RS14300 71e0f89ad378d33069b0dfc34ce859a4 567 PRINTS PR01165 Cytochrome c oxidase subunit I signature 300 315 1.4E-97 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CU254_RS14300 71e0f89ad378d33069b0dfc34ce859a4 567 PRINTS PR01165 Cytochrome c oxidase subunit I signature 435 456 1.4E-97 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CU254_RS14300 71e0f89ad378d33069b0dfc34ce859a4 567 PRINTS PR01165 Cytochrome c oxidase subunit I signature 204 223 1.4E-97 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CU254_RS14300 71e0f89ad378d33069b0dfc34ce859a4 567 PRINTS PR01165 Cytochrome c oxidase subunit I signature 385 404 1.4E-97 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CU254_RS14300 71e0f89ad378d33069b0dfc34ce859a4 567 PRINTS PR01165 Cytochrome c oxidase subunit I signature 73 96 1.4E-97 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CU254_RS14300 71e0f89ad378d33069b0dfc34ce859a4 567 PRINTS PR01165 Cytochrome c oxidase subunit I signature 143 155 1.4E-97 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CU254_RS14300 71e0f89ad378d33069b0dfc34ce859a4 567 PRINTS PR01165 Cytochrome c oxidase subunit I signature 26 51 1.4E-97 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CU254_RS14300 71e0f89ad378d33069b0dfc34ce859a4 567 PRINTS PR01165 Cytochrome c oxidase subunit I signature 100 124 1.4E-97 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CU254_RS14300 71e0f89ad378d33069b0dfc34ce859a4 567 PRINTS PR01165 Cytochrome c oxidase subunit I signature 175 193 1.4E-97 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CU254_RS14300 71e0f89ad378d33069b0dfc34ce859a4 567 PRINTS PR01165 Cytochrome c oxidase subunit I signature 254 275 1.4E-97 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CU254_RS14300 71e0f89ad378d33069b0dfc34ce859a4 567 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 28 531 7.1E-217 T 28-03-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 CU254_RS14300 71e0f89ad378d33069b0dfc34ce859a4 567 SUPERFAMILY SSF81442 24 534 1.31E-176 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CU254_RS14300 71e0f89ad378d33069b0dfc34ce859a4 567 Gene3D G3DSA:1.20.210.10 23 535 1.3E-197 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CU254_RS14300 71e0f89ad378d33069b0dfc34ce859a4 567 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 256 310 - T 28-03-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CU254_RS14300 71e0f89ad378d33069b0dfc34ce859a4 567 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 35 479 4.7E-150 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CU254_RS20550 f9a53883e28a4cc42b1f891e28b4e78d 1061 SUPERFAMILY SSF51246 331 449 1.83E-23 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CU254_RS20550 f9a53883e28a4cc42b1f891e28b4e78d 1061 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 487 504 - T 28-03-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CU254_RS20550 f9a53883e28a4cc42b1f891e28b4e78d 1061 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 111 319 1.5E-57 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CU254_RS20550 f9a53883e28a4cc42b1f891e28b4e78d 1061 Pfam PF00364 Biotin-requiring enzyme 476 530 1.6E-12 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CU254_RS20550 f9a53883e28a4cc42b1f891e28b4e78d 1061 SUPERFAMILY SSF52096 553 809 2.32E-49 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS20550 f9a53883e28a4cc42b1f891e28b4e78d 1061 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 282 289 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CU254_RS20550 f9a53883e28a4cc42b1f891e28b4e78d 1061 Gene3D G3DSA:3.40.50.20 1 114 1.3E-37 T 28-03-2018 CU254_RS20550 f9a53883e28a4cc42b1f891e28b4e78d 1061 Gene3D G3DSA:3.30.470.20 198 449 2.6E-82 T 28-03-2018 CU254_RS20550 f9a53883e28a4cc42b1f891e28b4e78d 1061 SUPERFAMILY SSF52440 3 108 5.97E-33 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CU254_RS20550 f9a53883e28a4cc42b1f891e28b4e78d 1061 Pfam PF02785 Biotin carboxylase C-terminal domain 336 447 1.6E-24 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CU254_RS20550 f9a53883e28a4cc42b1f891e28b4e78d 1061 SUPERFAMILY SSF56059 79 324 4.6E-57 T 28-03-2018 CU254_RS20550 f9a53883e28a4cc42b1f891e28b4e78d 1061 SUPERFAMILY SSF51230 463 530 3.27E-14 T 28-03-2018 IPR011053 Single hybrid motif CU254_RS20550 f9a53883e28a4cc42b1f891e28b4e78d 1061 Gene3D G3DSA:2.40.50.100 464 531 3.2E-14 T 28-03-2018 CU254_RS20550 f9a53883e28a4cc42b1f891e28b4e78d 1061 Gene3D G3DSA:3.30.1490.20 115 195 6.0E-16 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CU254_RS20550 f9a53883e28a4cc42b1f891e28b4e78d 1061 SMART SM00878 336 446 1.6E-29 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CU254_RS20550 f9a53883e28a4cc42b1f891e28b4e78d 1061 SUPERFAMILY SSF52096 778 1046 2.98E-64 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS20550 f9a53883e28a4cc42b1f891e28b4e78d 1061 Gene3D G3DSA:3.90.226.10 811 1046 8.6E-55 T 28-03-2018 CU254_RS20550 f9a53883e28a4cc42b1f891e28b4e78d 1061 Pfam PF00289 Biotin carboxylase, N-terminal domain 3 106 5.0E-31 T 28-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CU254_RS20550 f9a53883e28a4cc42b1f891e28b4e78d 1061 Gene3D G3DSA:3.90.226.10 539 810 6.5E-45 T 28-03-2018 CU254_RS20550 f9a53883e28a4cc42b1f891e28b4e78d 1061 Pfam PF01039 Carboxyl transferase domain 578 1046 1.4E-74 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 CU254_RS05150 27436b8c14aad7678b24c44c822fe89f 266 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 102 255 5.9E-13 T 28-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 CU254_RS05150 27436b8c14aad7678b24c44c822fe89f 266 SUPERFAMILY SSF46689 30 95 2.0E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS05150 27436b8c14aad7678b24c44c822fe89f 266 Gene3D G3DSA:1.10.10.60 9 89 1.2E-15 T 28-03-2018 CU254_RS05150 27436b8c14aad7678b24c44c822fe89f 266 SUPERFAMILY SSF48498 101 257 3.45E-22 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS05150 27436b8c14aad7678b24c44c822fe89f 266 Gene3D G3DSA:1.10.357.10 90 260 3.2E-39 T 28-03-2018 CU254_RS05150 27436b8c14aad7678b24c44c822fe89f 266 Pfam PF00440 Bacterial regulatory proteins, tetR family 39 83 5.2E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS25155 9a798843aa76ac3372853302b0dda9a5 99 SUPERFAMILY SSF140453 4 96 7.98E-16 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CU254_RS25155 9a798843aa76ac3372853302b0dda9a5 99 Gene3D G3DSA:1.10.287.1060 2 98 1.4E-12 T 28-03-2018 CU254_RS25155 9a798843aa76ac3372853302b0dda9a5 99 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 5 93 1.6E-14 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CU254_RS25155 9a798843aa76ac3372853302b0dda9a5 99 Pfam PF06013 Proteins of 100 residues with WXG 5 86 1.5E-11 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CU254_RS04875 2d8825de7e8552caec956f190f1b80b8 213 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 195 6.0E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS04875 2d8825de7e8552caec956f190f1b80b8 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 7.7E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS04875 2d8825de7e8552caec956f190f1b80b8 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 7.7E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS04875 2d8825de7e8552caec956f190f1b80b8 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 7.7E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS04875 2d8825de7e8552caec956f190f1b80b8 213 Pfam PF00072 Response regulator receiver domain 3 108 6.4E-17 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS04875 2d8825de7e8552caec956f190f1b80b8 213 SUPERFAMILY SSF52172 1 132 2.42E-20 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS04875 2d8825de7e8552caec956f190f1b80b8 213 SMART SM00448 1 120 6.6E-13 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS04875 2d8825de7e8552caec956f190f1b80b8 213 SMART SM00421 147 204 2.0E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS04875 2d8825de7e8552caec956f190f1b80b8 213 SUPERFAMILY SSF46894 136 197 8.16E-15 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS04875 2d8825de7e8552caec956f190f1b80b8 213 Gene3D G3DSA:3.40.50.2300 1 131 4.1E-23 T 28-03-2018 CU254_RS04875 2d8825de7e8552caec956f190f1b80b8 213 Gene3D G3DSA:1.10.10.10 132 213 2.9E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS40580 4af3e2a8bc91b1d55429d434f26dc113 490 SMART SM00304 235 287 3.2E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS40580 4af3e2a8bc91b1d55429d434f26dc113 490 SUPERFAMILY SSF55073 311 489 2.2E-44 T 28-03-2018 IPR029787 Nucleotide cyclase CU254_RS40580 4af3e2a8bc91b1d55429d434f26dc113 490 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 315 486 1.0E-25 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CU254_RS40580 4af3e2a8bc91b1d55429d434f26dc113 490 SMART SM00044 283 474 4.0E-10 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CU254_RS40580 4af3e2a8bc91b1d55429d434f26dc113 490 Pfam PF00672 HAMP domain 235 283 7.9E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS40580 4af3e2a8bc91b1d55429d434f26dc113 490 SUPERFAMILY SSF158472 235 284 7.32E-7 T 28-03-2018 CU254_RS40580 4af3e2a8bc91b1d55429d434f26dc113 490 Gene3D G3DSA:3.30.70.1230 305 490 1.1E-39 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CU254_RS04995 5a979c549188f2c2e7f703c17466068a 304 SMART SM00382 26 204 3.7E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS04995 5a979c549188f2c2e7f703c17466068a 304 ProSitePatterns PS00211 ABC transporters family signature. 128 142 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS04995 5a979c549188f2c2e7f703c17466068a 304 SUPERFAMILY SSF52540 2 218 6.16E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS04995 5a979c549188f2c2e7f703c17466068a 304 Gene3D G3DSA:3.40.50.300 1 253 1.1E-53 T 28-03-2018 CU254_RS04995 5a979c549188f2c2e7f703c17466068a 304 Pfam PF00005 ABC transporter 19 156 3.9E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS33850 9607dc686c7100403152fe55a94ffec4 594 SUPERFAMILY SSF57770 136 170 1.11E-11 T 28-03-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CU254_RS33850 9607dc686c7100403152fe55a94ffec4 594 Hamap MF_00098 Methionine--tRNA ligase [metG]. 1 588 37.097 T 28-03-2018 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CU254_RS33850 9607dc686c7100403152fe55a94ffec4 594 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 5 525 5.5E-144 T 28-03-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CU254_RS33850 9607dc686c7100403152fe55a94ffec4 594 Gene3D G3DSA:2.20.28.20 136 159 3.7E-17 T 28-03-2018 CU254_RS33850 9607dc686c7100403152fe55a94ffec4 594 Pfam PF09334 tRNA synthetases class I (M) 2 407 4.5E-144 T 28-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 CU254_RS33850 9607dc686c7100403152fe55a94ffec4 594 SUPERFAMILY SSF52374 170 395 1.33E-89 T 28-03-2018 CU254_RS33850 9607dc686c7100403152fe55a94ffec4 594 SUPERFAMILY SSF52374 4 135 1.33E-89 T 28-03-2018 CU254_RS33850 9607dc686c7100403152fe55a94ffec4 594 Gene3D G3DSA:1.10.730.10 384 579 6.0E-45 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CU254_RS33850 9607dc686c7100403152fe55a94ffec4 594 SUPERFAMILY SSF47323 396 523 1.25E-31 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CU254_RS33850 9607dc686c7100403152fe55a94ffec4 594 SUPERFAMILY SSF47323 551 577 1.25E-31 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CU254_RS33850 9607dc686c7100403152fe55a94ffec4 594 PRINTS PR01041 Methionyl-tRNA synthetase signature 3 16 1.0E-24 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CU254_RS33850 9607dc686c7100403152fe55a94ffec4 594 PRINTS PR01041 Methionyl-tRNA synthetase signature 289 304 1.0E-24 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CU254_RS33850 9607dc686c7100403152fe55a94ffec4 594 PRINTS PR01041 Methionyl-tRNA synthetase signature 84 95 1.0E-24 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CU254_RS33850 9607dc686c7100403152fe55a94ffec4 594 PRINTS PR01041 Methionyl-tRNA synthetase signature 395 406 1.0E-24 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CU254_RS33850 9607dc686c7100403152fe55a94ffec4 594 PRINTS PR01041 Methionyl-tRNA synthetase signature 36 50 1.0E-24 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CU254_RS33850 9607dc686c7100403152fe55a94ffec4 594 PRINTS PR01041 Methionyl-tRNA synthetase signature 249 260 1.0E-24 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CU254_RS33850 9607dc686c7100403152fe55a94ffec4 594 Gene3D G3DSA:2.170.220.10 160 246 4.9E-19 T 28-03-2018 CU254_RS33850 9607dc686c7100403152fe55a94ffec4 594 Gene3D G3DSA:3.40.50.620 1 71 2.2E-16 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS33850 9607dc686c7100403152fe55a94ffec4 594 Gene3D G3DSA:3.40.50.620 247 383 2.0E-22 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS08480 026a3855634e5406df981f5a79ed6a34 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 195 1.6E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS08480 026a3855634e5406df981f5a79ed6a34 214 Gene3D G3DSA:3.40.50.2300 1 131 2.4E-28 T 28-03-2018 CU254_RS08480 026a3855634e5406df981f5a79ed6a34 214 SMART SM00421 148 210 4.5E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS08480 026a3855634e5406df981f5a79ed6a34 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 1.4E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS08480 026a3855634e5406df981f5a79ed6a34 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 1.4E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS08480 026a3855634e5406df981f5a79ed6a34 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 1.4E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS08480 026a3855634e5406df981f5a79ed6a34 214 SUPERFAMILY SSF46894 132 195 9.86E-15 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS08480 026a3855634e5406df981f5a79ed6a34 214 SMART SM00448 1 120 1.8E-12 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS08480 026a3855634e5406df981f5a79ed6a34 214 SUPERFAMILY SSF52172 2 136 2.7E-19 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS08480 026a3855634e5406df981f5a79ed6a34 214 Gene3D G3DSA:1.10.10.10 132 214 1.6E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS08480 026a3855634e5406df981f5a79ed6a34 214 Pfam PF00072 Response regulator receiver domain 3 108 8.6E-18 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS19150 efdcb745dc00de5f7dd7d15b3a995f94 228 SUPERFAMILY SSF46689 15 78 1.8E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS19150 efdcb745dc00de5f7dd7d15b3a995f94 228 Gene3D G3DSA:1.10.357.10 76 227 4.3E-33 T 28-03-2018 CU254_RS19150 efdcb745dc00de5f7dd7d15b3a995f94 228 Gene3D G3DSA:1.10.10.60 2 75 1.3E-14 T 28-03-2018 CU254_RS19150 efdcb745dc00de5f7dd7d15b3a995f94 228 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 90 225 3.2E-17 T 28-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 CU254_RS19150 efdcb745dc00de5f7dd7d15b3a995f94 228 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 69 3.5E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS19150 efdcb745dc00de5f7dd7d15b3a995f94 228 SUPERFAMILY SSF48498 90 225 1.11E-21 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS38685 abaa945cec6a672d63cbfe69b82cc3e4 393 Pfam PF13936 Helix-turn-helix domain 66 105 1.8E-13 T 28-03-2018 IPR025246 Transposase IS30-like HTH domain CU254_RS38685 abaa945cec6a672d63cbfe69b82cc3e4 393 Pfam PF00665 Integrase core domain 239 346 2.9E-10 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CU254_RS38685 abaa945cec6a672d63cbfe69b82cc3e4 393 Gene3D G3DSA:3.30.420.10 232 393 6.6E-21 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS38685 abaa945cec6a672d63cbfe69b82cc3e4 393 SUPERFAMILY SSF53098 239 388 9.26E-25 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS38685 abaa945cec6a672d63cbfe69b82cc3e4 393 ProSitePatterns PS01043 Transposases, IS30 family, signature. 333 349 - T 28-03-2018 IPR001598 Transposase, IS30, conserved site GO:0003677|GO:0004803|GO:0006313 CU254_RS38685 abaa945cec6a672d63cbfe69b82cc3e4 393 Gene3D G3DSA:1.10.10.60 66 109 1.9E-11 T 28-03-2018 CU254_RS08760 abaa945cec6a672d63cbfe69b82cc3e4 393 Pfam PF13936 Helix-turn-helix domain 66 105 1.8E-13 T 28-03-2018 IPR025246 Transposase IS30-like HTH domain CU254_RS08760 abaa945cec6a672d63cbfe69b82cc3e4 393 Pfam PF00665 Integrase core domain 239 346 2.9E-10 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CU254_RS08760 abaa945cec6a672d63cbfe69b82cc3e4 393 Gene3D G3DSA:3.30.420.10 232 393 6.6E-21 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS08760 abaa945cec6a672d63cbfe69b82cc3e4 393 SUPERFAMILY SSF53098 239 388 9.26E-25 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS08760 abaa945cec6a672d63cbfe69b82cc3e4 393 ProSitePatterns PS01043 Transposases, IS30 family, signature. 333 349 - T 28-03-2018 IPR001598 Transposase, IS30, conserved site GO:0003677|GO:0004803|GO:0006313 CU254_RS08760 abaa945cec6a672d63cbfe69b82cc3e4 393 Gene3D G3DSA:1.10.10.60 66 109 1.9E-11 T 28-03-2018 CU254_RS30605 81d520448d5491ed9f2c218fbba6fba3 506 Pfam PF07905 Purine catabolism regulatory protein-like family 6 118 1.8E-19 T 28-03-2018 IPR012914 Purine catabolism PurC-like domain CU254_RS30605 81d520448d5491ed9f2c218fbba6fba3 506 Gene3D G3DSA:3.40.1390.20 9 116 7.9E-4 T 28-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like CU254_RS30605 81d520448d5491ed9f2c218fbba6fba3 506 Pfam PF13556 PucR C-terminal helix-turn-helix domain 441 496 1.2E-21 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CU254_RS30605 81d520448d5491ed9f2c218fbba6fba3 506 Gene3D G3DSA:1.10.10.60 429 478 1.5E-6 T 28-03-2018 CU254_RS30025 40bedbd16b02a0c14df5ce7621088e23 254 SMART SM00862 16 94 6.7E-9 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS30025 40bedbd16b02a0c14df5ce7621088e23 254 Pfam PF03704 Bacterial transcriptional activator domain 101 246 3.8E-39 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CU254_RS30025 40bedbd16b02a0c14df5ce7621088e23 254 SUPERFAMILY SSF46894 3 93 9.64E-13 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS30025 40bedbd16b02a0c14df5ce7621088e23 254 Pfam PF00486 Transcriptional regulatory protein, C terminal 27 80 1.5E-9 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS30025 40bedbd16b02a0c14df5ce7621088e23 254 SMART SM01043 101 246 3.3E-37 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CU254_RS30025 40bedbd16b02a0c14df5ce7621088e23 254 Gene3D G3DSA:1.10.10.10 7 102 2.8E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS30025 40bedbd16b02a0c14df5ce7621088e23 254 SUPERFAMILY SSF48452 99 249 4.17E-30 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS30025 40bedbd16b02a0c14df5ce7621088e23 254 Gene3D G3DSA:1.25.40.10 103 253 9.5E-20 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS36195 27bedb13d1d98444d57b82254772f8da 1060 Gene3D G3DSA:1.25.40.10 937 1046 0.0026 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS36195 27bedb13d1d98444d57b82254772f8da 1060 Gene3D G3DSA:1.25.40.10 728 936 1.2E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS36195 27bedb13d1d98444d57b82254772f8da 1060 SUPERFAMILY SSF48452 744 919 9.21E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS36195 27bedb13d1d98444d57b82254772f8da 1060 Pfam PF13401 AAA domain 279 391 2.5E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS36195 27bedb13d1d98444d57b82254772f8da 1060 SUPERFAMILY SSF52540 256 526 6.59E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS36195 27bedb13d1d98444d57b82254772f8da 1060 Gene3D G3DSA:1.10.10.10 9 98 1.6E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS36195 27bedb13d1d98444d57b82254772f8da 1060 PRINTS PR00364 Disease resistance protein signature 282 297 2.1E-5 T 28-03-2018 CU254_RS36195 27bedb13d1d98444d57b82254772f8da 1060 PRINTS PR00364 Disease resistance protein signature 360 374 2.1E-5 T 28-03-2018 CU254_RS36195 27bedb13d1d98444d57b82254772f8da 1060 PRINTS PR00364 Disease resistance protein signature 466 480 2.1E-5 T 28-03-2018 CU254_RS36195 27bedb13d1d98444d57b82254772f8da 1060 Pfam PF00486 Transcriptional regulatory protein, C terminal 27 78 1.9E-7 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS36195 27bedb13d1d98444d57b82254772f8da 1060 Pfam PF03704 Bacterial transcriptional activator domain 97 239 3.3E-40 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CU254_RS36195 27bedb13d1d98444d57b82254772f8da 1060 SMART SM00862 16 90 1.7E-10 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS36195 27bedb13d1d98444d57b82254772f8da 1060 SMART SM01043 97 242 8.1E-45 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CU254_RS36195 27bedb13d1d98444d57b82254772f8da 1060 SUPERFAMILY SSF46894 3 90 1.13E-10 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS36195 27bedb13d1d98444d57b82254772f8da 1060 Gene3D G3DSA:3.40.50.300 255 407 1.1E-14 T 28-03-2018 CU254_RS36195 27bedb13d1d98444d57b82254772f8da 1060 Gene3D G3DSA:1.25.40.10 99 254 5.3E-21 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS36195 27bedb13d1d98444d57b82254772f8da 1060 SUPERFAMILY SSF48452 92 260 3.49E-33 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS30050 b254d4de26e9d33795496806e0874d7f 1572 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 270 8.3E-80 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CU254_RS30050 b254d4de26e9d33795496806e0874d7f 1572 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1451 1466 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CU254_RS30050 b254d4de26e9d33795496806e0874d7f 1572 SMART SM00823 Phosphopantetheine attachment site 1424 1496 8.6E-28 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS30050 b254d4de26e9d33795496806e0874d7f 1572 Gene3D G3DSA:3.40.366.10 536 683 6.2E-43 T 28-03-2018 CU254_RS30050 b254d4de26e9d33795496806e0874d7f 1572 Gene3D G3DSA:3.30.70.250 684 728 1.9E-17 T 28-03-2018 CU254_RS30050 b254d4de26e9d33795496806e0874d7f 1572 Gene3D G3DSA:3.40.47.10 285 445 5.0E-58 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS30050 b254d4de26e9d33795496806e0874d7f 1572 SUPERFAMILY SSF55048 669 733 2.09E-11 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CU254_RS30050 b254d4de26e9d33795496806e0874d7f 1572 Gene3D G3DSA:3.40.47.10 24 275 1.8E-77 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS30050 b254d4de26e9d33795496806e0874d7f 1572 Pfam PF00550 Phosphopantetheine attachment site 1426 1492 2.6E-9 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS30050 b254d4de26e9d33795496806e0874d7f 1572 Pfam PF08990 Erythronolide synthase docking 2 27 5.0E-13 T 28-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 CU254_RS30050 b254d4de26e9d33795496806e0874d7f 1572 SMART SM00825 Beta-ketoacyl synthase 36 447 4.3E-202 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CU254_RS30050 b254d4de26e9d33795496806e0874d7f 1572 Gene3D G3DSA:1.10.1200.10 1408 1502 1.9E-17 T 28-03-2018 CU254_RS30050 b254d4de26e9d33795496806e0874d7f 1572 SUPERFAMILY SSF101173 3 34 9.68E-7 T 28-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 CU254_RS30050 b254d4de26e9d33795496806e0874d7f 1572 SUPERFAMILY SSF52151 734 831 1.18E-63 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CU254_RS30050 b254d4de26e9d33795496806e0874d7f 1572 SUPERFAMILY SSF52151 539 668 1.18E-63 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CU254_RS30050 b254d4de26e9d33795496806e0874d7f 1572 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1150 1324 1.0E-38 T 28-03-2018 CU254_RS30050 b254d4de26e9d33795496806e0874d7f 1572 Gene3D G3DSA:3.40.50.720 959 1115 0.19 T 28-03-2018 CU254_RS30050 b254d4de26e9d33795496806e0874d7f 1572 Pfam PF08659 KR domain 1150 1322 9.0E-50 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS30050 b254d4de26e9d33795496806e0874d7f 1572 SUPERFAMILY SSF47336 1416 1500 1.57E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS30050 b254d4de26e9d33795496806e0874d7f 1572 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 397 506 8.6E-14 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS30050 b254d4de26e9d33795496806e0874d7f 1572 Pfam PF00698 Acyl transferase domain 541 859 4.4E-85 T 28-03-2018 IPR014043 Acyl transferase CU254_RS30050 b254d4de26e9d33795496806e0874d7f 1572 SUPERFAMILY SSF51735 948 1138 2.83E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS30050 b254d4de26e9d33795496806e0874d7f 1572 SUPERFAMILY SSF53901 29 393 5.77E-98 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS30050 b254d4de26e9d33795496806e0874d7f 1572 Gene3D G3DSA:3.40.366.10 729 849 7.7E-25 T 28-03-2018 CU254_RS30050 b254d4de26e9d33795496806e0874d7f 1572 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 278 394 2.0E-40 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CU254_RS30050 b254d4de26e9d33795496806e0874d7f 1572 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 543 842 1.2E-108 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CU254_RS30050 b254d4de26e9d33795496806e0874d7f 1572 Gene3D G3DSA:3.40.50.720 1142 1396 1.4E-55 T 28-03-2018 CU254_RS30050 b254d4de26e9d33795496806e0874d7f 1572 SUPERFAMILY SSF51735 1145 1383 2.23E-49 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS30050 b254d4de26e9d33795496806e0874d7f 1572 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 183 199 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CU254_RS14495 e0dbdf12133540bb9bef6d5496b09a87 306 Gene3D G3DSA:3.20.20.70 1 305 5.7E-82 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS14495 e0dbdf12133540bb9bef6d5496b09a87 306 Pfam PF00682 HMGL-like 5 284 9.3E-40 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CU254_RS14495 e0dbdf12133540bb9bef6d5496b09a87 306 SUPERFAMILY SSF51569 1 302 3.52E-61 T 28-03-2018 CU254_RS18445 e40fb02f4c9503efa8c523185a5fcc02 411 SUPERFAMILY SSF103473 15 407 1.11E-60 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS18445 e40fb02f4c9503efa8c523185a5fcc02 411 Pfam PF07690 Major Facilitator Superfamily 34 370 5.1E-47 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS18445 e40fb02f4c9503efa8c523185a5fcc02 411 Gene3D G3DSA:1.20.1250.20 18 212 2.2E-30 T 28-03-2018 CU254_RS18445 e40fb02f4c9503efa8c523185a5fcc02 411 ProSitePatterns PS00216 Sugar transport proteins signature 1. 79 95 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CU254_RS18445 e40fb02f4c9503efa8c523185a5fcc02 411 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 23 393 9.7E-83 T 28-03-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 CU254_RS18445 e40fb02f4c9503efa8c523185a5fcc02 411 Gene3D G3DSA:1.20.1250.20 213 408 3.5E-13 T 28-03-2018 CU254_RS20175 639ca8d3911da9dcc38245e87dff5b8f 265 Gene3D G3DSA:1.10.260.40 2 113 2.4E-12 T 28-03-2018 CU254_RS20175 639ca8d3911da9dcc38245e87dff5b8f 265 SUPERFAMILY SSF47413 5 66 5.07E-12 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS20175 639ca8d3911da9dcc38245e87dff5b8f 265 SMART SM00530 12 67 4.6E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS20175 639ca8d3911da9dcc38245e87dff5b8f 265 Pfam PF13560 Helix-turn-helix domain 9 70 3.8E-10 T 28-03-2018 CU254_RS38645 0804212f97fe6a99218818e2474669f0 429 SUPERFAMILY SSF53901 298 428 1.42E-30 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS38645 0804212f97fe6a99218818e2474669f0 429 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 14 428 6.2E-123 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CU254_RS38645 0804212f97fe6a99218818e2474669f0 429 Gene3D G3DSA:3.40.47.10 292 427 3.0E-25 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS38645 0804212f97fe6a99218818e2474669f0 429 Pfam PF00108 Thiolase, N-terminal domain 12 278 2.4E-51 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CU254_RS38645 0804212f97fe6a99218818e2474669f0 429 Pfam PF02803 Thiolase, C-terminal domain 289 429 4.3E-33 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CU254_RS38645 0804212f97fe6a99218818e2474669f0 429 PIRSF PIRSF000429 6 429 5.1E-108 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CU254_RS38645 0804212f97fe6a99218818e2474669f0 429 SUPERFAMILY SSF53901 12 286 3.42E-58 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS38645 0804212f97fe6a99218818e2474669f0 429 Gene3D G3DSA:3.40.47.10 4 291 5.3E-40 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS33930 a30dd95c7c933d72b7aa223fb019f5ec 520 PRINTS PR00738 Glycosyl hydrolase family 20 signature 448 464 9.3E-46 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CU254_RS33930 a30dd95c7c933d72b7aa223fb019f5ec 520 PRINTS PR00738 Glycosyl hydrolase family 20 signature 299 317 9.3E-46 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CU254_RS33930 a30dd95c7c933d72b7aa223fb019f5ec 520 PRINTS PR00738 Glycosyl hydrolase family 20 signature 466 483 9.3E-46 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CU254_RS33930 a30dd95c7c933d72b7aa223fb019f5ec 520 PRINTS PR00738 Glycosyl hydrolase family 20 signature 121 141 9.3E-46 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CU254_RS33930 a30dd95c7c933d72b7aa223fb019f5ec 520 PRINTS PR00738 Glycosyl hydrolase family 20 signature 321 334 9.3E-46 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CU254_RS33930 a30dd95c7c933d72b7aa223fb019f5ec 520 PRINTS PR00738 Glycosyl hydrolase family 20 signature 163 180 9.3E-46 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CU254_RS33930 a30dd95c7c933d72b7aa223fb019f5ec 520 PRINTS PR00738 Glycosyl hydrolase family 20 signature 251 268 9.3E-46 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CU254_RS33930 a30dd95c7c933d72b7aa223fb019f5ec 520 PRINTS PR00738 Glycosyl hydrolase family 20 signature 192 213 9.3E-46 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CU254_RS33930 a30dd95c7c933d72b7aa223fb019f5ec 520 SUPERFAMILY SSF55545 30 168 8.5E-27 T 28-03-2018 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CU254_RS33930 a30dd95c7c933d72b7aa223fb019f5ec 520 Gene3D G3DSA:3.20.20.80 158 517 4.1E-119 T 28-03-2018 CU254_RS33930 a30dd95c7c933d72b7aa223fb019f5ec 520 SUPERFAMILY SSF51445 169 513 6.94E-107 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS33930 a30dd95c7c933d72b7aa223fb019f5ec 520 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 169 484 8.1E-85 T 28-03-2018 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822 CU254_RS33930 a30dd95c7c933d72b7aa223fb019f5ec 520 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 35 166 3.2E-18 T 28-03-2018 IPR015882 Beta-hexosaminidase, bacteial type, N-terminal KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822 CU254_RS33930 a30dd95c7c933d72b7aa223fb019f5ec 520 Gene3D G3DSA:3.30.379.10 27 157 1.7E-27 T 28-03-2018 CU254_RS35885 c9c7c9973055861a4ccb4caeca4ca6f9 441 Pfam PF07690 Major Facilitator Superfamily 253 438 2.7E-15 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS35885 c9c7c9973055861a4ccb4caeca4ca6f9 441 ProSitePatterns PS00217 Sugar transport proteins signature 2. 126 151 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CU254_RS35885 c9c7c9973055861a4ccb4caeca4ca6f9 441 Gene3D G3DSA:1.20.1250.20 13 222 3.1E-20 T 28-03-2018 CU254_RS35885 c9c7c9973055861a4ccb4caeca4ca6f9 441 SUPERFAMILY SSF103473 17 429 1.26E-60 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS35885 c9c7c9973055861a4ccb4caeca4ca6f9 441 ProSitePatterns PS00216 Sugar transport proteins signature 1. 299 316 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CU254_RS35885 c9c7c9973055861a4ccb4caeca4ca6f9 441 Pfam PF00083 Sugar (and other) transporter 19 232 6.1E-16 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CU254_RS35885 c9c7c9973055861a4ccb4caeca4ca6f9 441 Gene3D G3DSA:1.20.1250.20 223 436 4.2E-27 T 28-03-2018 CU254_RS11490 aa0ab1f186e2966051c29f88afbce041 1105 SUPERFAMILY SSF52440 559 681 1.28E-44 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CU254_RS11490 aa0ab1f186e2966051c29f88afbce041 1105 Gene3D G3DSA:3.40.50.20 537 661 1.4E-57 T 28-03-2018 CU254_RS11490 aa0ab1f186e2966051c29f88afbce041 1105 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 2.5E-60 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CU254_RS11490 aa0ab1f186e2966051c29f88afbce041 1105 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 2.5E-60 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CU254_RS11490 aa0ab1f186e2966051c29f88afbce041 1105 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 2.5E-60 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CU254_RS11490 aa0ab1f186e2966051c29f88afbce041 1105 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 297 326 2.5E-60 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CU254_RS11490 aa0ab1f186e2966051c29f88afbce041 1105 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 2.5E-60 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CU254_RS11490 aa0ab1f186e2966051c29f88afbce041 1105 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 379 397 2.5E-60 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CU254_RS11490 aa0ab1f186e2966051c29f88afbce041 1105 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 2.5E-60 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CU254_RS11490 aa0ab1f186e2966051c29f88afbce041 1105 SMART SM00851 977 1069 2.3E-28 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CU254_RS11490 aa0ab1f186e2966051c29f88afbce041 1105 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 425 545 1.3E-35 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CU254_RS11490 aa0ab1f186e2966051c29f88afbce041 1105 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 845 852 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CU254_RS11490 aa0ab1f186e2966051c29f88afbce041 1105 SUPERFAMILY SSF56059 128 400 3.54E-103 T 28-03-2018 CU254_RS11490 aa0ab1f186e2966051c29f88afbce041 1105 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 297 304 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CU254_RS11490 aa0ab1f186e2966051c29f88afbce041 1105 SUPERFAMILY SSF56059 680 954 1.48E-93 T 28-03-2018 CU254_RS11490 aa0ab1f186e2966051c29f88afbce041 1105 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1090 12.949 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CU254_RS11490 aa0ab1f186e2966051c29f88afbce041 1105 Gene3D G3DSA:1.10.1030.10 410 536 1.0E-40 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CU254_RS11490 aa0ab1f186e2966051c29f88afbce041 1105 SMART SM01096 422 545 1.6E-57 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CU254_RS11490 aa0ab1f186e2966051c29f88afbce041 1105 SUPERFAMILY SSF48108 396 548 7.85E-41 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CU254_RS11490 aa0ab1f186e2966051c29f88afbce041 1105 Gene3D G3DSA:3.30.470.20 120 402 2.2E-65 T 28-03-2018 CU254_RS11490 aa0ab1f186e2966051c29f88afbce041 1105 SUPERFAMILY SSF52440 1 127 2.16E-46 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CU254_RS11490 aa0ab1f186e2966051c29f88afbce041 1105 Gene3D G3DSA:3.40.50.1380 956 1101 2.9E-47 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CU254_RS11490 aa0ab1f186e2966051c29f88afbce041 1105 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1078 0.0 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CU254_RS11490 aa0ab1f186e2966051c29f88afbce041 1105 Pfam PF02142 MGS-like domain 978 1069 8.0E-22 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CU254_RS11490 aa0ab1f186e2966051c29f88afbce041 1105 SUPERFAMILY SSF52335 963 1098 4.84E-35 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CU254_RS11490 aa0ab1f186e2966051c29f88afbce041 1105 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 334 1.5E-67 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CU254_RS11490 aa0ab1f186e2966051c29f88afbce041 1105 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 680 881 1.7E-32 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CU254_RS11490 aa0ab1f186e2966051c29f88afbce041 1105 Gene3D G3DSA:3.30.470.20 753 955 7.8E-32 T 28-03-2018 CU254_RS11490 aa0ab1f186e2966051c29f88afbce041 1105 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 716 730 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CU254_RS11490 aa0ab1f186e2966051c29f88afbce041 1105 Gene3D G3DSA:3.40.50.20 4 110 1.2E-35 T 28-03-2018 CU254_RS11490 aa0ab1f186e2966051c29f88afbce041 1105 Gene3D G3DSA:3.30.1490.20 662 752 1.8E-25 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CU254_RS04545 3c18d889982b33c635aeff862267b06d 962 Gene3D G3DSA:1.25.40.10 366 623 1.8E-16 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS04545 3c18d889982b33c635aeff862267b06d 962 Gene3D G3DSA:1.25.40.10 630 891 9.4E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS04545 3c18d889982b33c635aeff862267b06d 962 SUPERFAMILY SSF48452 576 610 5.82E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS04545 3c18d889982b33c635aeff862267b06d 962 SUPERFAMILY SSF48452 647 729 5.82E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS04545 3c18d889982b33c635aeff862267b06d 962 SMART SM00421 900 957 8.6E-24 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS04545 3c18d889982b33c635aeff862267b06d 962 Pfam PF13191 AAA ATPase domain 40 206 6.7E-23 T 28-03-2018 CU254_RS04545 3c18d889982b33c635aeff862267b06d 962 Gene3D G3DSA:1.10.10.10 902 962 4.8E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS04545 3c18d889982b33c635aeff862267b06d 962 Gene3D G3DSA:1.10.10.10 280 365 0.028 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS04545 3c18d889982b33c635aeff862267b06d 962 Pfam PF00196 Bacterial regulatory proteins, luxR family 902 956 6.7E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS04545 3c18d889982b33c635aeff862267b06d 962 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 933 945 4.2E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS04545 3c18d889982b33c635aeff862267b06d 962 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 903 917 4.2E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS04545 3c18d889982b33c635aeff862267b06d 962 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 917 933 4.2E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS04545 3c18d889982b33c635aeff862267b06d 962 Gene3D G3DSA:3.40.50.300 41 238 1.1E-8 T 28-03-2018 CU254_RS04545 3c18d889982b33c635aeff862267b06d 962 ProSitePatterns PS00622 LuxR-type HTH domain signature. 917 944 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS04545 3c18d889982b33c635aeff862267b06d 962 SUPERFAMILY SSF48452 421 527 6.64E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS04545 3c18d889982b33c635aeff862267b06d 962 SUPERFAMILY SSF52540 40 301 1.39E-9 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS04545 3c18d889982b33c635aeff862267b06d 962 SUPERFAMILY SSF46894 894 961 5.44E-19 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS31030 6e42d2f44bdc580ef0364f2642396043 196 PIRSF PIRSF016661 11 195 2.6E-40 T 28-03-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 CU254_RS31030 6e42d2f44bdc580ef0364f2642396043 196 Pfam PF02632 BioY family 48 186 3.0E-36 T 28-03-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 CU254_RS35375 f4f14d06ee21739699641fc693d3c103 312 Pfam PF13378 Enolase C-terminal domain-like 78 277 5.3E-35 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CU254_RS35375 f4f14d06ee21739699641fc693d3c103 312 Hamap MF_00470 o-succinylbenzoate synthase [menC]. 1 279 22.067 T 28-03-2018 IPR010196 o-Succinylbenzoate synthase, MenC type1 GO:0000287|GO:0009234|GO:0016836 KEGG: 00010+4.2.1.11|KEGG: 00130+4.2.1.113|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-5837|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CU254_RS35375 f4f14d06ee21739699641fc693d3c103 312 SUPERFAMILY SSF51604 62 277 1.44E-49 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CU254_RS35375 f4f14d06ee21739699641fc693d3c103 312 SMART SM00922 77 173 1.4E-22 T 28-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CU254_RS35375 f4f14d06ee21739699641fc693d3c103 312 Gene3D G3DSA:3.20.20.120 85 277 9.5E-41 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CU254_RS35375 f4f14d06ee21739699641fc693d3c103 312 Gene3D G3DSA:3.30.390.10 1 84 1.1E-39 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CU254_RS11365 962887e6f7b27199b7d6d140c164affe 89 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 82 2.2E-25 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CU254_RS11365 962887e6f7b27199b7d6d140c164affe 89 SUPERFAMILY SSF55594 1 87 3.14E-21 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CU254_RS11365 962887e6f7b27199b7d6d140c164affe 89 Pfam PF00381 PTS HPr component phosphorylation site 3 83 1.0E-23 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CU254_RS11365 962887e6f7b27199b7d6d140c164affe 89 Gene3D G3DSA:3.30.1340.10 1 88 7.5E-27 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CU254_RS11365 962887e6f7b27199b7d6d140c164affe 89 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 28-03-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site CU254_RS11365 962887e6f7b27199b7d6d140c164affe 89 PRINTS PR00107 Phosphocarrier protein signature 39 54 1.4E-10 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CU254_RS11365 962887e6f7b27199b7d6d140c164affe 89 PRINTS PR00107 Phosphocarrier protein signature 54 71 1.4E-10 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CU254_RS11365 962887e6f7b27199b7d6d140c164affe 89 PRINTS PR00107 Phosphocarrier protein signature 13 29 1.4E-10 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CU254_RS30350 e81f1ec43898879289bae26275ef5602 493 SMART SM01009 199 314 2.3E-45 T 28-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal CU254_RS30350 e81f1ec43898879289bae26275ef5602 493 SMART SM00478 324 481 7.0E-19 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CU254_RS30350 e81f1ec43898879289bae26275ef5602 493 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 137 179 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CU254_RS30350 e81f1ec43898879289bae26275ef5602 493 Pfam PF06029 AlkA N-terminal domain 200 314 1.2E-29 T 28-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal CU254_RS30350 e81f1ec43898879289bae26275ef5602 493 Pfam PF12833 Helix-turn-helix domain 106 185 1.1E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS30350 e81f1ec43898879289bae26275ef5602 493 SUPERFAMILY SSF57884 2 83 2.88E-31 T 28-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 CU254_RS30350 e81f1ec43898879289bae26275ef5602 493 Gene3D G3DSA:1.10.10.60 138 195 1.5E-10 T 28-03-2018 CU254_RS30350 e81f1ec43898879289bae26275ef5602 493 Gene3D G3DSA:1.10.340.30 300 444 6.3E-29 T 28-03-2018 CU254_RS30350 e81f1ec43898879289bae26275ef5602 493 Pfam PF02805 Metal binding domain of Ada 8 71 1.5E-28 T 28-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 CU254_RS30350 e81f1ec43898879289bae26275ef5602 493 Gene3D G3DSA:1.10.1670.10 445 485 2.7E-12 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CU254_RS30350 e81f1ec43898879289bae26275ef5602 493 Gene3D G3DSA:3.30.310.20 199 299 5.2E-36 T 28-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal CU254_RS30350 e81f1ec43898879289bae26275ef5602 493 SUPERFAMILY SSF55945 200 295 2.98E-25 T 28-03-2018 CU254_RS30350 e81f1ec43898879289bae26275ef5602 493 SUPERFAMILY SSF46689 137 187 3.4E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS30350 e81f1ec43898879289bae26275ef5602 493 Gene3D G3DSA:1.10.10.60 80 137 2.1E-4 T 28-03-2018 CU254_RS30350 e81f1ec43898879289bae26275ef5602 493 SMART SM00342 100 183 5.7E-19 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS30350 e81f1ec43898879289bae26275ef5602 493 SUPERFAMILY SSF48150 305 478 3.49E-39 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CU254_RS30350 e81f1ec43898879289bae26275ef5602 493 Gene3D G3DSA:3.40.10.10 1 73 3.6E-25 T 28-03-2018 IPR035451 Ada-like domain CU254_RS09840 c8ae02eb0702b8013dab63332354a093 589 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 63 342 5.2E-65 T 28-03-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 CU254_RS09840 c8ae02eb0702b8013dab63332354a093 589 Gene3D G3DSA:2.60.120.260 386 576 9.0E-38 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS09840 c8ae02eb0702b8013dab63332354a093 589 Gene3D G3DSA:3.40.50.1820 32 385 1.7E-37 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS09840 c8ae02eb0702b8013dab63332354a093 589 SUPERFAMILY SSF49785 436 577 2.55E-34 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS09840 c8ae02eb0702b8013dab63332354a093 589 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 33 45 5.4E-11 T 28-03-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 CU254_RS09840 c8ae02eb0702b8013dab63332354a093 589 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 49 59 5.4E-11 T 28-03-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 CU254_RS09840 c8ae02eb0702b8013dab63332354a093 589 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 84 100 5.4E-11 T 28-03-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 CU254_RS09840 c8ae02eb0702b8013dab63332354a093 589 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 67 76 5.4E-11 T 28-03-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 CU254_RS09840 c8ae02eb0702b8013dab63332354a093 589 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 369 569 6.5E-39 T 28-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CU254_RS09840 c8ae02eb0702b8013dab63332354a093 589 SUPERFAMILY SSF53474 29 392 8.4E-78 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS09840 c8ae02eb0702b8013dab63332354a093 589 SMART SM00939 357 572 4.1E-41 T 28-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CU254_RS39475 3726e85e35c3657219582ab27bd34da5 273 Gene3D G3DSA:3.40.50.300 4 213 1.9E-43 T 28-03-2018 CU254_RS39475 3726e85e35c3657219582ab27bd34da5 273 Pfam PF00005 ABC transporter 24 152 4.1E-20 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS39475 3726e85e35c3657219582ab27bd34da5 273 SUPERFAMILY SSF52540 5 211 2.5E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS39475 3726e85e35c3657219582ab27bd34da5 273 SMART SM00382 33 201 4.5E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS39475 3726e85e35c3657219582ab27bd34da5 273 ProSitePatterns PS00211 ABC transporters family signature. 125 139 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS31580 7298184b1da715cab24eebc973d51b64 524 Gene3D G3DSA:2.60.40.420 390 524 2.7E-34 T 28-03-2018 IPR008972 Cupredoxin CU254_RS31580 7298184b1da715cab24eebc973d51b64 524 Pfam PF07731 Multicopper oxidase 413 522 4.4E-23 T 28-03-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 CU254_RS31580 7298184b1da715cab24eebc973d51b64 524 Gene3D G3DSA:2.60.40.420 215 389 5.0E-31 T 28-03-2018 IPR008972 Cupredoxin CU254_RS31580 7298184b1da715cab24eebc973d51b64 524 ProSitePatterns PS00080 Multicopper oxidases signature 2. 506 517 - T 28-03-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 CU254_RS31580 7298184b1da715cab24eebc973d51b64 524 SUPERFAMILY SSF49503 409 521 2.06E-30 T 28-03-2018 IPR008972 Cupredoxin CU254_RS31580 7298184b1da715cab24eebc973d51b64 524 Pfam PF07732 Multicopper oxidase 80 140 1.3E-9 T 28-03-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 CU254_RS31580 7298184b1da715cab24eebc973d51b64 524 Pfam PF07732 Multicopper oxidase 167 215 2.1E-4 T 28-03-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 CU254_RS31580 7298184b1da715cab24eebc973d51b64 524 Gene3D G3DSA:2.60.40.420 39 214 3.1E-31 T 28-03-2018 IPR008972 Cupredoxin CU254_RS31580 7298184b1da715cab24eebc973d51b64 524 ProSitePatterns PS00079 Multicopper oxidases signature 1. 501 521 - T 28-03-2018 IPR033138 Multicopper oxidases, conserved site CU254_RS31580 7298184b1da715cab24eebc973d51b64 524 SUPERFAMILY SSF49503 219 351 3.13E-21 T 28-03-2018 IPR008972 Cupredoxin CU254_RS31580 7298184b1da715cab24eebc973d51b64 524 SUPERFAMILY SSF49503 48 216 2.4E-23 T 28-03-2018 IPR008972 Cupredoxin CU254_RS19305 612b0d3ac2de528cd24f5b7813368b2e 188 SUPERFAMILY SSF88946 8 109 2.83E-20 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS19305 612b0d3ac2de528cd24f5b7813368b2e 188 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 26 178 7.3E-21 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS19305 612b0d3ac2de528cd24f5b7813368b2e 188 SUPERFAMILY SSF88659 124 179 3.05E-13 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS19305 612b0d3ac2de528cd24f5b7813368b2e 188 Pfam PF08281 Sigma-70, region 4 128 177 1.1E-14 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS19305 612b0d3ac2de528cd24f5b7813368b2e 188 Gene3D G3DSA:1.10.1740.10 2 85 1.1E-18 T 28-03-2018 CU254_RS19305 612b0d3ac2de528cd24f5b7813368b2e 188 Gene3D G3DSA:1.10.10.10 86 187 4.4E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS19305 612b0d3ac2de528cd24f5b7813368b2e 188 Pfam PF04542 Sigma-70 region 2 40 95 6.3E-11 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS18075 7015301df603cf4037827f4fd4388437 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 58 1.2E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS18075 7015301df603cf4037827f4fd4388437 194 Gene3D G3DSA:1.10.10.60 1 58 1.8E-15 T 28-03-2018 CU254_RS18075 7015301df603cf4037827f4fd4388437 194 Gene3D G3DSA:1.10.357.10 59 194 3.2E-21 T 28-03-2018 CU254_RS18075 7015301df603cf4037827f4fd4388437 194 SUPERFAMILY SSF48498 78 189 4.45E-21 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS18075 7015301df603cf4037827f4fd4388437 194 SUPERFAMILY SSF46689 2 81 4.74E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS19060 37e552cad553c4eda6954494f0a15ae8 214 Gene3D G3DSA:3.40.50.150 6 213 5.6E-39 T 28-03-2018 CU254_RS19060 37e552cad553c4eda6954494f0a15ae8 214 SUPERFAMILY SSF53335 12 200 1.7E-34 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS19060 37e552cad553c4eda6954494f0a15ae8 214 Pfam PF13649 Methyltransferase domain 53 141 1.3E-18 T 28-03-2018 CU254_RS32095 a9c589ec97ec4ceb8d018bc94a48e8f4 468 Pfam PF12476 Protein of unknown function (DUF3696) 406 452 6.3E-7 T 28-03-2018 IPR022532 Domain of unknown function DUF3696, C-terminal CU254_RS32095 a9c589ec97ec4ceb8d018bc94a48e8f4 468 PIRSF PIRSF034888 262 461 2.3E-31 T 28-03-2018 IPR014592 Predicted P-loop ATP-binding protein, VCA0200 CU254_RS32095 a9c589ec97ec4ceb8d018bc94a48e8f4 468 PIRSF PIRSF034888 1 190 2.1E-15 T 28-03-2018 IPR014592 Predicted P-loop ATP-binding protein, VCA0200 CU254_RS32095 a9c589ec97ec4ceb8d018bc94a48e8f4 468 Gene3D G3DSA:3.40.50.300 1 397 5.3E-15 T 28-03-2018 CU254_RS32095 a9c589ec97ec4ceb8d018bc94a48e8f4 468 SUPERFAMILY SSF52540 1 91 1.29E-10 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS32095 a9c589ec97ec4ceb8d018bc94a48e8f4 468 SUPERFAMILY SSF52540 292 396 1.29E-10 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS32095 a9c589ec97ec4ceb8d018bc94a48e8f4 468 Pfam PF13175 AAA ATPase domain 1 75 1.4E-8 T 28-03-2018 CU254_RS32095 a9c589ec97ec4ceb8d018bc94a48e8f4 468 Pfam PF13175 AAA ATPase domain 305 387 1.9E-14 T 28-03-2018 CU254_RS18015 c56d1ebc9e3e45b2fd42ed6c7cb489e5 326 Pfam PF13519 von Willebrand factor type A domain 91 203 1.8E-19 T 28-03-2018 IPR002035 von Willebrand factor, type A CU254_RS18015 c56d1ebc9e3e45b2fd42ed6c7cb489e5 326 Gene3D G3DSA:3.40.50.410 83 301 9.6E-41 T 28-03-2018 IPR002035 von Willebrand factor, type A CU254_RS18015 c56d1ebc9e3e45b2fd42ed6c7cb489e5 326 Pfam PF07584 Aerotolerance regulator N-terminal 5 78 8.1E-8 T 28-03-2018 IPR024163 Aerotolerance regulator, N-terminal CU254_RS18015 c56d1ebc9e3e45b2fd42ed6c7cb489e5 326 SMART SM00327 88 291 2.4E-21 T 28-03-2018 IPR002035 von Willebrand factor, type A CU254_RS18015 c56d1ebc9e3e45b2fd42ed6c7cb489e5 326 SUPERFAMILY SSF53300 85 288 2.86E-30 T 28-03-2018 IPR002035 von Willebrand factor, type A CU254_RS33875 4ccd2290ac4992c898688751f30a03ca 412 TIGRFAM TIGR00553 pabB: aminodeoxychorismate synthase, component I 73 402 5.4E-102 T 28-03-2018 IPR005802 Para-aminobenzoate synthase, component I GO:0009396 KEGG: 00790+2.6.1.85|MetaCyc: PWY-6543 CU254_RS33875 4ccd2290ac4992c898688751f30a03ca 412 SUPERFAMILY SSF56322 66 406 7.2E-96 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CU254_RS33875 4ccd2290ac4992c898688751f30a03ca 412 Pfam PF00425 chorismate binding enzyme 149 398 6.9E-77 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal CU254_RS33875 4ccd2290ac4992c898688751f30a03ca 412 PRINTS PR00095 Anthranilate synthase component I signature 340 354 7.4E-12 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CU254_RS33875 4ccd2290ac4992c898688751f30a03ca 412 PRINTS PR00095 Anthranilate synthase component I signature 260 273 7.4E-12 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CU254_RS33875 4ccd2290ac4992c898688751f30a03ca 412 PRINTS PR00095 Anthranilate synthase component I signature 246 259 7.4E-12 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CU254_RS33875 4ccd2290ac4992c898688751f30a03ca 412 PRINTS PR00095 Anthranilate synthase component I signature 355 369 7.4E-12 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CU254_RS33875 4ccd2290ac4992c898688751f30a03ca 412 Gene3D G3DSA:3.60.120.10 42 411 2.5E-106 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CU254_RS14120 8848fbe1a47fa768812ac83f0ad8854c 284 Gene3D G3DSA:3.40.50.720 1 282 4.5E-42 T 28-03-2018 CU254_RS14120 8848fbe1a47fa768812ac83f0ad8854c 284 SUPERFAMILY SSF51735 2 229 6.91E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS14120 8848fbe1a47fa768812ac83f0ad8854c 284 Pfam PF00106 short chain dehydrogenase 2 135 3.1E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS14120 8848fbe1a47fa768812ac83f0ad8854c 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 117 133 1.4E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS14120 8848fbe1a47fa768812ac83f0ad8854c 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 1.4E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS14120 8848fbe1a47fa768812ac83f0ad8854c 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 19 1.4E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS22640 07d9f43f5b1aada5d235c75ac05c6eb4 225 Gene3D G3DSA:3.60.15.10 18 223 2.3E-35 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS22640 07d9f43f5b1aada5d235c75ac05c6eb4 225 SUPERFAMILY SSF56281 25 221 4.2E-45 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS22640 07d9f43f5b1aada5d235c75ac05c6eb4 225 SMART SM00849 36 204 2.9E-32 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS22640 07d9f43f5b1aada5d235c75ac05c6eb4 225 Pfam PF00753 Metallo-beta-lactamase superfamily 33 190 1.0E-15 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS11980 b8f6fe06ed5b9170425b998f0e1fa83f 273 Gene3D G3DSA:3.20.20.210 69 267 2.7E-48 T 28-03-2018 CU254_RS11980 b8f6fe06ed5b9170425b998f0e1fa83f 273 Gene3D G3DSA:3.20.20.210 1 68 3.1E-24 T 28-03-2018 CU254_RS11980 b8f6fe06ed5b9170425b998f0e1fa83f 273 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 68 263 7.7E-58 T 28-03-2018 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CU254_RS11980 b8f6fe06ed5b9170425b998f0e1fa83f 273 SUPERFAMILY SSF51726 1 262 1.57E-55 T 28-03-2018 CU254_RS39225 3a10ba550157837aa30cedbce1d514d8 143 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 2 116 15.787 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CU254_RS39225 3a10ba550157837aa30cedbce1d514d8 143 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 7 112 4.6E-14 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CU254_RS39225 3a10ba550157837aa30cedbce1d514d8 143 SUPERFAMILY SSF54211 2 115 8.09E-21 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CU254_RS39225 3a10ba550157837aa30cedbce1d514d8 143 Gene3D G3DSA:3.30.230.10 1 119 2.2E-29 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CU254_RS39225 3a10ba550157837aa30cedbce1d514d8 143 Pfam PF00825 Ribonuclease P 2 113 1.4E-24 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CU254_RS03420 11be3e720c8b2cea78d854167ebe4ec8 165 SUPERFAMILY SSF52255 4 161 3.92E-67 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CU254_RS03420 11be3e720c8b2cea78d854167ebe4ec8 165 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 5 159 5.6E-66 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CU254_RS03420 11be3e720c8b2cea78d854167ebe4ec8 165 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 5 156 33.256 T 28-03-2018 IPR033747 Class I PurE CU254_RS03420 11be3e720c8b2cea78d854167ebe4ec8 165 Gene3D G3DSA:3.40.50.7700 1 161 2.4E-72 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CU254_RS03420 11be3e720c8b2cea78d854167ebe4ec8 165 SMART SM01001 3 152 6.1E-98 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CU254_RS03420 11be3e720c8b2cea78d854167ebe4ec8 165 PIRSF PIRSF001338 1 163 3.6E-70 T 28-03-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 CU254_RS03420 11be3e720c8b2cea78d854167ebe4ec8 165 Pfam PF00731 AIR carboxylase 4 149 3.4E-66 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CU254_RS05855 b703589576957fafbd61aa832582a571 576 Gene3D G3DSA:3.30.300.30 437 542 6.9E-10 T 28-03-2018 CU254_RS05855 b703589576957fafbd61aa832582a571 576 Gene3D G3DSA:2.30.38.10 343 434 1.5E-11 T 28-03-2018 CU254_RS05855 b703589576957fafbd61aa832582a571 576 Gene3D G3DSA:3.40.50.980 1 163 2.9E-21 T 28-03-2018 CU254_RS05855 b703589576957fafbd61aa832582a571 576 Gene3D G3DSA:3.40.50.980 164 333 1.9E-34 T 28-03-2018 CU254_RS05855 b703589576957fafbd61aa832582a571 576 SUPERFAMILY SSF56801 7 553 7.2E-83 T 28-03-2018 CU254_RS05855 b703589576957fafbd61aa832582a571 576 Pfam PF00501 AMP-binding enzyme 35 440 9.4E-61 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS05855 b703589576957fafbd61aa832582a571 576 ProSitePatterns PS00455 Putative AMP-binding domain signature. 158 169 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS14475 c9cfc46cfde5cfd5e0ae3eb3112bc68a 523 Gene3D G3DSA:3.40.50.980 180 336 2.1E-37 T 28-03-2018 CU254_RS14475 c9cfc46cfde5cfd5e0ae3eb3112bc68a 523 Pfam PF13193 AMP-binding enzyme C-terminal domain 429 497 1.5E-17 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS14475 c9cfc46cfde5cfd5e0ae3eb3112bc68a 523 Gene3D G3DSA:3.30.300.30 415 521 3.7E-25 T 28-03-2018 CU254_RS14475 c9cfc46cfde5cfd5e0ae3eb3112bc68a 523 SUPERFAMILY SSF56801 8 518 1.27E-130 T 28-03-2018 CU254_RS14475 c9cfc46cfde5cfd5e0ae3eb3112bc68a 523 ProSitePatterns PS00455 Putative AMP-binding domain signature. 174 185 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS14475 c9cfc46cfde5cfd5e0ae3eb3112bc68a 523 Gene3D G3DSA:3.40.50.980 9 179 1.7E-40 T 28-03-2018 CU254_RS14475 c9cfc46cfde5cfd5e0ae3eb3112bc68a 523 Pfam PF00501 AMP-binding enzyme 21 420 2.3E-82 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS14475 c9cfc46cfde5cfd5e0ae3eb3112bc68a 523 Gene3D G3DSA:2.30.38.10 337 414 3.0E-21 T 28-03-2018 CU254_RS12340 af391f433e6db45e8211e8e380d2ab1b 446 Pfam PF00083 Sugar (and other) transporter 24 222 1.6E-17 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CU254_RS12340 af391f433e6db45e8211e8e380d2ab1b 446 Pfam PF00083 Sugar (and other) transporter 261 428 4.8E-8 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CU254_RS12340 af391f433e6db45e8211e8e380d2ab1b 446 ProSitePatterns PS00217 Sugar transport proteins signature 2. 131 156 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CU254_RS12340 af391f433e6db45e8211e8e380d2ab1b 446 SUPERFAMILY SSF103473 7 431 1.31E-60 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS12340 af391f433e6db45e8211e8e380d2ab1b 446 Gene3D G3DSA:1.20.1250.20 234 446 1.5E-26 T 28-03-2018 CU254_RS12340 af391f433e6db45e8211e8e380d2ab1b 446 Gene3D G3DSA:1.20.1250.20 12 226 4.4E-21 T 28-03-2018 CU254_RS12355 dd3c64a66edacbfe36c89fce73924498 317 Gene3D G3DSA:2.40.100.10 100 263 5.8E-37 T 28-03-2018 IPR029000 Cyclophilin-like domain CU254_RS12355 dd3c64a66edacbfe36c89fce73924498 317 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 12 235 1.7E-42 T 28-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D CU254_RS12355 dd3c64a66edacbfe36c89fce73924498 317 Gene3D G3DSA:3.30.1360.40 1 93 6.5E-24 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CU254_RS12355 dd3c64a66edacbfe36c89fce73924498 317 SUPERFAMILY SSF50891 135 258 4.17E-23 T 28-03-2018 IPR029000 Cyclophilin-like domain CU254_RS12355 dd3c64a66edacbfe36c89fce73924498 317 SMART SM00796 11 245 3.9E-50 T 28-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D CU254_RS12355 dd3c64a66edacbfe36c89fce73924498 317 SUPERFAMILY SSF160467 12 106 1.7E-18 T 28-03-2018 CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2822 2837 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 Gene3D G3DSA:3.40.47.10 1674 1932 3.3E-75 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 184 200 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 Gene3D G3DSA:3.40.47.10 25 276 5.8E-81 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 SUPERFAMILY SSF53901 33 390 1.76E-101 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 SUPERFAMILY SSF53901 422 432 1.76E-101 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 SUPERFAMILY SSF53901 1672 2042 7.32E-92 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 SUPERFAMILY SSF53474 2825 2863 3.11E-30 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 SUPERFAMILY SSF53474 2909 3147 3.11E-30 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1928 2045 5.0E-40 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 279 394 1.2E-42 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 Gene3D G3DSA:3.40.366.10 722 840 4.6E-26 T 28-03-2018 CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 Pfam PF00698 Acyl transferase domain 2196 2503 8.4E-56 T 28-03-2018 IPR014043 Acyl transferase CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 Pfam PF00698 Acyl transferase domain 546 853 1.5E-55 T 28-03-2018 IPR014043 Acyl transferase CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 Pfam PF14765 Polyketide synthase dehydratase 902 1176 5.6E-53 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 SUPERFAMILY SSF52151 2193 2325 5.23E-59 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 SUPERFAMILY SSF52151 2385 2476 5.23E-59 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1834 1850 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 Gene3D G3DSA:3.40.50.1820 2876 3150 5.2E-20 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 Gene3D G3DSA:3.30.70.250 2331 2374 8.2E-16 T 28-03-2018 CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 Gene3D G3DSA:3.40.50.720 1313 1590 2.7E-47 T 28-03-2018 CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 Gene3D G3DSA:3.10.129.10 905 1029 2.7E-6 T 28-03-2018 CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1610 1625 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 Gene3D G3DSA:3.40.47.10 286 445 1.4E-60 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 Gene3D G3DSA:3.40.47.10 1935 2096 7.1E-57 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 Gene3D G3DSA:3.30.70.250 678 721 8.4E-18 T 28-03-2018 CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 SMART SM00825 Beta-ketoacyl synthase 1677 2098 1.3E-180 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 SMART SM00825 Beta-ketoacyl synthase 37 447 3.7E-204 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 Pfam PF00975 Thioesterase domain 2939 3133 1.1E-10 T 28-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 Pfam PF08659 KR domain 1316 1487 1.6E-56 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 Gene3D G3DSA:1.10.1200.10 2766 2871 7.1E-18 T 28-03-2018 CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2048 2162 2.5E-12 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 397 512 3.3E-19 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1316 1489 5.1E-50 T 28-03-2018 CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 SUPERFAMILY SSF51735 1312 1554 5.09E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 SUPERFAMILY SSF55048 2324 2383 5.62E-9 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2197 2486 8.6E-90 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 547 835 5.1E-108 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 SMART SM01294 1584 1651 2.4E-7 T 28-03-2018 CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 SMART SM01294 2796 2863 7.8E-5 T 28-03-2018 CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 Gene3D G3DSA:1.10.1200.10 1591 1673 3.7E-20 T 28-03-2018 CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 SUPERFAMILY SSF47336 1578 1690 3.4E-26 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 SMART SM00823 Phosphopantetheine attachment site 1583 1655 4.7E-33 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 SMART SM00823 Phosphopantetheine attachment site 2795 2867 1.9E-25 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 Gene3D G3DSA:3.40.366.10 2375 2490 2.7E-21 T 28-03-2018 CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 Pfam PF00550 Phosphopantetheine attachment site 2798 2863 1.4E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 Pfam PF00550 Phosphopantetheine attachment site 1586 1651 6.8E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 35 271 3.6E-82 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1675 1920 2.3E-80 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 SMART SM00824 Thioesterase 2934 3146 8.9E-75 T 28-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 Gene3D G3DSA:3.40.366.10 543 677 1.7E-39 T 28-03-2018 CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 Gene3D G3DSA:3.40.366.10 2193 2330 2.1E-39 T 28-03-2018 CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 SUPERFAMILY SSF52151 723 829 2.04E-70 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 SUPERFAMILY SSF52151 544 663 2.04E-70 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 SUPERFAMILY SSF55048 668 730 4.71E-11 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 SMART SM00826 902 1065 1.9E-81 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 SMART SM00826 2549 2679 5.4E-18 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS30090 c050a5a4826b0725fead816871d3ea31 3150 SUPERFAMILY SSF51735 1183 1305 9.85E-15 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS00890 b1844ba33b882546922f6fb789c68851 131 Gene3D G3DSA:1.10.260.40 1 120 1.7E-18 T 28-03-2018 CU254_RS00890 b1844ba33b882546922f6fb789c68851 131 Pfam PF01381 Helix-turn-helix 15 67 1.3E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS00890 b1844ba33b882546922f6fb789c68851 131 SMART SM00530 14 69 2.4E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS00890 b1844ba33b882546922f6fb789c68851 131 SUPERFAMILY SSF47413 8 71 7.88E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS00665 87a3a081d9b019e76eb03980f9dd74ee 901 SUPERFAMILY SSF55785 263 355 3.54E-12 T 28-03-2018 IPR000014 PAS domain CU254_RS00665 87a3a081d9b019e76eb03980f9dd74ee 901 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 481 641 7.5E-39 T 28-03-2018 IPR000160 GGDEF domain CU254_RS00665 87a3a081d9b019e76eb03980f9dd74ee 901 Gene3D G3DSA:3.30.450.20 136 248 4.2E-14 T 28-03-2018 CU254_RS00665 87a3a081d9b019e76eb03980f9dd74ee 901 Gene3D G3DSA:3.30.450.20 353 494 7.9E-26 T 28-03-2018 CU254_RS00665 87a3a081d9b019e76eb03980f9dd74ee 901 SMART SM00091 140 206 7.9E-5 T 28-03-2018 IPR000014 PAS domain CU254_RS00665 87a3a081d9b019e76eb03980f9dd74ee 901 SMART SM00091 355 422 4.4E-7 T 28-03-2018 IPR000014 PAS domain CU254_RS00665 87a3a081d9b019e76eb03980f9dd74ee 901 SMART SM00091 252 319 8.0E-4 T 28-03-2018 IPR000014 PAS domain CU254_RS00665 87a3a081d9b019e76eb03980f9dd74ee 901 SUPERFAMILY SSF55073 490 643 1.02E-41 T 28-03-2018 IPR029787 Nucleotide cyclase CU254_RS00665 87a3a081d9b019e76eb03980f9dd74ee 901 SUPERFAMILY SSF141868 657 900 6.28E-88 T 28-03-2018 IPR001633 EAL domain CU254_RS00665 87a3a081d9b019e76eb03980f9dd74ee 901 Pfam PF13188 PAS domain 141 176 3.7E-8 T 28-03-2018 IPR000014 PAS domain CU254_RS00665 87a3a081d9b019e76eb03980f9dd74ee 901 SMART SM00052 652 898 6.4E-112 T 28-03-2018 IPR001633 EAL domain CU254_RS00665 87a3a081d9b019e76eb03980f9dd74ee 901 Gene3D G3DSA:3.30.450.20 41 135 0.16 T 28-03-2018 CU254_RS00665 87a3a081d9b019e76eb03980f9dd74ee 901 Pfam PF00563 EAL domain 658 893 5.6E-77 T 28-03-2018 IPR001633 EAL domain CU254_RS00665 87a3a081d9b019e76eb03980f9dd74ee 901 Pfam PF00989 PAS fold 255 339 2.3E-7 T 28-03-2018 IPR013767 PAS fold GO:0006355 CU254_RS00665 87a3a081d9b019e76eb03980f9dd74ee 901 Pfam PF00990 Diguanylate cyclase, GGDEF domain 485 637 1.6E-41 T 28-03-2018 IPR000160 GGDEF domain CU254_RS00665 87a3a081d9b019e76eb03980f9dd74ee 901 SUPERFAMILY SSF55785 347 472 4.51E-18 T 28-03-2018 IPR000014 PAS domain CU254_RS00665 87a3a081d9b019e76eb03980f9dd74ee 901 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 256 322 2.4E-6 T 28-03-2018 IPR000014 PAS domain CU254_RS00665 87a3a081d9b019e76eb03980f9dd74ee 901 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 139 248 3.1E-8 T 28-03-2018 IPR000014 PAS domain CU254_RS00665 87a3a081d9b019e76eb03980f9dd74ee 901 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 352 479 4.1E-12 T 28-03-2018 IPR000014 PAS domain CU254_RS00665 87a3a081d9b019e76eb03980f9dd74ee 901 Gene3D G3DSA:3.30.70.270 495 649 3.6E-55 T 28-03-2018 CU254_RS00665 87a3a081d9b019e76eb03980f9dd74ee 901 Gene3D G3DSA:3.30.450.20 249 352 5.4E-16 T 28-03-2018 CU254_RS00665 87a3a081d9b019e76eb03980f9dd74ee 901 SUPERFAMILY SSF55785 134 240 1.05E-11 T 28-03-2018 IPR000014 PAS domain CU254_RS00665 87a3a081d9b019e76eb03980f9dd74ee 901 Gene3D G3DSA:3.20.20.450 650 900 1.5E-100 T 28-03-2018 IPR001633 EAL domain CU254_RS00665 87a3a081d9b019e76eb03980f9dd74ee 901 SMART SM00267 474 642 6.3E-60 T 28-03-2018 IPR000160 GGDEF domain CU254_RS00665 87a3a081d9b019e76eb03980f9dd74ee 901 Pfam PF13426 PAS domain 365 473 8.8E-14 T 28-03-2018 IPR000014 PAS domain CU254_RS38855 5c3b36ffb780f69ca4ac7a142283b7de 691 Gene3D G3DSA:2.120.10.30 431 659 2.6E-6 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CU254_RS38855 5c3b36ffb780f69ca4ac7a142283b7de 691 SUPERFAMILY SSF63829 574 635 8.17E-9 T 28-03-2018 CU254_RS38855 5c3b36ffb780f69ca4ac7a142283b7de 691 SUPERFAMILY SSF63829 485 540 8.17E-9 T 28-03-2018 CU254_RS38855 5c3b36ffb780f69ca4ac7a142283b7de 691 SUPERFAMILY SSF63829 304 434 8.17E-9 T 28-03-2018 CU254_RS38855 5c3b36ffb780f69ca4ac7a142283b7de 691 Pfam PF05787 Bacterial protein of unknown function (DUF839) 98 648 3.8E-165 T 28-03-2018 IPR008557 Protein of unknown function DUF839 CU254_RS23230 d102cd238c05f521aa163b4f4bc6e4f1 341 Gene3D G3DSA:1.10.10.10 179 221 1.1E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS23230 d102cd238c05f521aa163b4f4bc6e4f1 341 SUPERFAMILY SSF54909 237 315 8.31E-6 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS23230 d102cd238c05f521aa163b4f4bc6e4f1 341 Pfam PF13404 AsnC-type helix-turn-helix domain 183 217 1.7E-10 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS23230 d102cd238c05f521aa163b4f4bc6e4f1 341 Pfam PF13404 AsnC-type helix-turn-helix domain 7 47 1.6E-10 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS23230 d102cd238c05f521aa163b4f4bc6e4f1 341 SUPERFAMILY SSF54909 66 147 2.68E-12 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS23230 d102cd238c05f521aa163b4f4bc6e4f1 341 Gene3D G3DSA:3.30.70.920 224 319 1.0E-9 T 28-03-2018 CU254_RS23230 d102cd238c05f521aa163b4f4bc6e4f1 341 Gene3D G3DSA:1.10.10.10 1 52 3.1E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS23230 d102cd238c05f521aa163b4f4bc6e4f1 341 Gene3D G3DSA:3.30.70.920 62 151 5.1E-15 T 28-03-2018 CU254_RS23230 d102cd238c05f521aa163b4f4bc6e4f1 341 Pfam PF01037 Lrp/AsnC ligand binding domain 71 139 1.1E-10 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CU254_RS23230 d102cd238c05f521aa163b4f4bc6e4f1 341 Pfam PF01037 Lrp/AsnC ligand binding domain 250 302 4.3E-7 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CU254_RS23230 d102cd238c05f521aa163b4f4bc6e4f1 341 SUPERFAMILY SSF46785 181 221 7.21E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS23230 d102cd238c05f521aa163b4f4bc6e4f1 341 SMART SM00344 182 282 6.6E-8 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CU254_RS23230 d102cd238c05f521aa163b4f4bc6e4f1 341 SMART SM00344 6 110 1.8E-4 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CU254_RS23230 d102cd238c05f521aa163b4f4bc6e4f1 341 SUPERFAMILY SSF46785 6 76 1.62E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS39865 2d7e07df0c45a895ebed424f48ebc2c5 393 Gene3D G3DSA:1.20.5.510 177 214 2.7E-5 T 28-03-2018 CU254_RS39985 c3011eded585a025b8fa66190f01eedc 208 SUPERFAMILY SSF88659 139 201 2.43E-16 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS39985 c3011eded585a025b8fa66190f01eedc 208 Gene3D G3DSA:1.10.10.10 116 202 1.9E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS39985 c3011eded585a025b8fa66190f01eedc 208 Pfam PF04542 Sigma-70 region 2 54 121 1.3E-6 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS39985 c3011eded585a025b8fa66190f01eedc 208 Pfam PF04545 Sigma-70, region 4 148 197 8.0E-16 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS39985 c3011eded585a025b8fa66190f01eedc 208 SMART SM00421 149 207 0.0089 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS39985 c3011eded585a025b8fa66190f01eedc 208 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 50 199 6.8E-22 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS39985 c3011eded585a025b8fa66190f01eedc 208 Gene3D G3DSA:1.10.1740.10 41 115 1.1E-10 T 28-03-2018 CU254_RS39985 c3011eded585a025b8fa66190f01eedc 208 SUPERFAMILY SSF88946 50 131 2.2E-9 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS39985 c3011eded585a025b8fa66190f01eedc 208 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 48 201 1.2E-47 T 28-03-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 CU254_RS02105 fb642f01a40e97bff50b9a9b68df17c1 181 SUPERFAMILY SSF64263 1 117 3.53E-45 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS02105 fb642f01a40e97bff50b9a9b68df17c1 181 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS02105 fb642f01a40e97bff50b9a9b68df17c1 181 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 25.285 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS02105 fb642f01a40e97bff50b9a9b68df17c1 181 Gene3D G3DSA:3.90.1030.10 1 117 5.1E-45 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS02105 fb642f01a40e97bff50b9a9b68df17c1 181 TIGRFAM TIGR00059 L17: ribosomal protein bL17 9 116 1.7E-40 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS02105 fb642f01a40e97bff50b9a9b68df17c1 181 Pfam PF01196 Ribosomal protein L17 21 116 4.5E-36 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS30495 ac1ec5d21db74ef8d0ae384b2a38352b 355 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 86 290 2.2E-20 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CU254_RS30495 ac1ec5d21db74ef8d0ae384b2a38352b 355 SUPERFAMILY SSF52540 56 297 7.76E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS30495 ac1ec5d21db74ef8d0ae384b2a38352b 355 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 346 144.991 T 28-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 CU254_RS30495 ac1ec5d21db74ef8d0ae384b2a38352b 355 SMART SM00382 97 264 9.3E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS30495 ac1ec5d21db74ef8d0ae384b2a38352b 355 Gene3D G3DSA:3.40.50.300 24 291 1.2E-53 T 28-03-2018 CU254_RS05780 d84b4f68859e736c1500664261b4143a 125 SMART SM00347 4 105 1.1E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS05780 d84b4f68859e736c1500664261b4143a 125 SUPERFAMILY SSF46785 5 122 4.31E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS05780 d84b4f68859e736c1500664261b4143a 125 Gene3D G3DSA:1.10.10.10 1 124 1.9E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS05780 d84b4f68859e736c1500664261b4143a 125 Pfam PF12802 MarR family 13 69 9.3E-8 T 28-03-2018 CU254_RS08500 6a5b598cf994908195dde93229a1fd2a 362 SUPERFAMILY SSF52343 135 269 1.7E-30 T 28-03-2018 CU254_RS08500 6a5b598cf994908195dde93229a1fd2a 362 PRINTS PR00410 Phenol hydroxylase reductase family signature 146 165 4.2E-9 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CU254_RS08500 6a5b598cf994908195dde93229a1fd2a 362 PRINTS PR00410 Phenol hydroxylase reductase family signature 236 244 4.2E-9 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CU254_RS08500 6a5b598cf994908195dde93229a1fd2a 362 PRINTS PR00410 Phenol hydroxylase reductase family signature 69 81 4.2E-9 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CU254_RS08500 6a5b598cf994908195dde93229a1fd2a 362 Gene3D G3DSA:2.40.30.10 36 132 7.0E-20 T 28-03-2018 CU254_RS08500 6a5b598cf994908195dde93229a1fd2a 362 SUPERFAMILY SSF54292 260 361 1.76E-16 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CU254_RS08500 6a5b598cf994908195dde93229a1fd2a 362 SUPERFAMILY SSF63380 41 137 1.15E-22 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CU254_RS08500 6a5b598cf994908195dde93229a1fd2a 362 Pfam PF00970 Oxidoreductase FAD-binding domain 44 135 8.1E-11 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CU254_RS08500 6a5b598cf994908195dde93229a1fd2a 362 Pfam PF00175 Oxidoreductase NAD-binding domain 147 250 3.6E-15 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CU254_RS08500 6a5b598cf994908195dde93229a1fd2a 362 Gene3D G3DSA:3.10.20.30 267 362 2.1E-12 T 28-03-2018 IPR012675 Beta-grasp domain CU254_RS08500 6a5b598cf994908195dde93229a1fd2a 362 Gene3D G3DSA:3.40.50.80 134 266 3.2E-25 T 28-03-2018 CU254_RS04340 d1ec28c928a7ec925f276d52a1f6031f 468 Pfam PF00773 RNB domain 46 351 2.9E-47 T 28-03-2018 CU254_RS04340 d1ec28c928a7ec925f276d52a1f6031f 468 SMART SM00955 46 364 2.4E-64 T 28-03-2018 CU254_RS04340 d1ec28c928a7ec925f276d52a1f6031f 468 SUPERFAMILY SSF50249 11 408 3.48E-92 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CU254_RS04340 d1ec28c928a7ec925f276d52a1f6031f 468 Gene3D G3DSA:2.40.50.140 410 468 1.9E-19 T 28-03-2018 CU254_RS21505 ac27c49f20475074c1d776745e39f8e0 211 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 11 207 38.971 T 28-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CU254_RS21505 ac27c49f20475074c1d776745e39f8e0 211 Pfam PF01174 SNO glutamine amidotransferase family 13 208 1.3E-56 T 28-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CU254_RS21505 ac27c49f20475074c1d776745e39f8e0 211 Gene3D G3DSA:3.40.50.880 9 211 1.4E-49 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS21505 ac27c49f20475074c1d776745e39f8e0 211 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 11 206 4.8E-70 T 28-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CU254_RS21505 ac27c49f20475074c1d776745e39f8e0 211 PIRSF PIRSF005639 6 211 1.7E-71 T 28-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CU254_RS21505 ac27c49f20475074c1d776745e39f8e0 211 ProSitePatterns PS01236 PdxT/SNO family family signature. 48 58 - T 28-03-2018 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CU254_RS21505 ac27c49f20475074c1d776745e39f8e0 211 SUPERFAMILY SSF52317 11 209 1.03E-47 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS22155 2b4d0368c79e7ede71549ab29769c38e 147 Gene3D G3DSA:3.10.180.10 1 146 1.6E-24 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS22155 2b4d0368c79e7ede71549ab29769c38e 147 SUPERFAMILY SSF54593 3 137 1.93E-24 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS22155 2b4d0368c79e7ede71549ab29769c38e 147 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 132 6.9E-13 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CU254_RS02270 e7e13f68132cff39c1adfd86ee22d9c4 167 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 24 150 1.5E-23 T 28-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 CU254_RS02270 e7e13f68132cff39c1adfd86ee22d9c4 167 SUPERFAMILY SSF52540 32 144 1.06E-15 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS02270 e7e13f68132cff39c1adfd86ee22d9c4 167 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 20 147 2.1E-31 T 28-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 CU254_RS02270 e7e13f68132cff39c1adfd86ee22d9c4 167 Gene3D G3DSA:3.40.50.300 13 166 1.2E-47 T 28-03-2018 CU254_RS10475 ef8b2709e0451b410db6bf690b283bfb 84 SUPERFAMILY SSF160443 4 81 1.83E-5 T 28-03-2018 IPR002625 Smr domain CU254_RS10475 ef8b2709e0451b410db6bf690b283bfb 84 Pfam PF01713 Smr domain 5 82 2.0E-12 T 28-03-2018 IPR002625 Smr domain CU254_RS11640 d5df3ad1dfd1b6080b16ce371969f821 324 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 6 323 1.2E-100 T 28-03-2018 IPR019949 Luciferase family oxidoreductase, group 1 CU254_RS11640 d5df3ad1dfd1b6080b16ce371969f821 324 Gene3D G3DSA:3.20.20.30 9 324 1.3E-65 T 28-03-2018 CU254_RS11640 d5df3ad1dfd1b6080b16ce371969f821 324 SUPERFAMILY SSF51679 5 324 2.22E-64 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS11640 d5df3ad1dfd1b6080b16ce371969f821 324 Pfam PF00296 Luciferase-like monooxygenase 19 301 3.5E-31 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS19730 08a92c0ceebc0591e39d7bc6c6a72248 521 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 304 317 - T 28-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CU254_RS19730 08a92c0ceebc0591e39d7bc6c6a72248 521 Gene3D G3DSA:3.40.50.300 1 269 8.9E-64 T 28-03-2018 CU254_RS19730 08a92c0ceebc0591e39d7bc6c6a72248 521 Gene3D G3DSA:3.40.50.300 272 521 6.0E-70 T 28-03-2018 CU254_RS19730 08a92c0ceebc0591e39d7bc6c6a72248 521 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 266 1.2E-5 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CU254_RS19730 08a92c0ceebc0591e39d7bc6c6a72248 521 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 494 521 0.0054 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CU254_RS19730 08a92c0ceebc0591e39d7bc6c6a72248 521 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS19730 08a92c0ceebc0591e39d7bc6c6a72248 521 Pfam PF00005 ABC transporter 21 182 3.9E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS19730 08a92c0ceebc0591e39d7bc6c6a72248 521 Pfam PF00005 ABC transporter 291 443 3.1E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS19730 08a92c0ceebc0591e39d7bc6c6a72248 521 SUPERFAMILY SSF52540 8 254 7.99E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS19730 08a92c0ceebc0591e39d7bc6c6a72248 521 SMART SM00382 30 232 2.0E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS19730 08a92c0ceebc0591e39d7bc6c6a72248 521 SMART SM00382 300 500 7.4E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS19730 08a92c0ceebc0591e39d7bc6c6a72248 521 SUPERFAMILY SSF52540 276 513 1.57E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS19730 08a92c0ceebc0591e39d7bc6c6a72248 521 ProSitePatterns PS00211 ABC transporters family signature. 415 429 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS34135 e0bf2841c9b8354697cf7cc8d1dad67d 420 Gene3D G3DSA:2.170.190.11 69 152 2.4E-30 T 28-03-2018 CU254_RS34135 e0bf2841c9b8354697cf7cc8d1dad67d 420 SUPERFAMILY SSF53218 188 334 9.16E-33 T 28-03-2018 IPR001453 MoaB/Mog domain CU254_RS34135 e0bf2841c9b8354697cf7cc8d1dad67d 420 Gene3D G3DSA:3.90.105.10 35 68 1.5E-5 T 28-03-2018 CU254_RS34135 e0bf2841c9b8354697cf7cc8d1dad67d 420 SMART SM00852 191 330 1.1E-26 T 28-03-2018 IPR001453 MoaB/Mog domain CU254_RS34135 e0bf2841c9b8354697cf7cc8d1dad67d 420 Pfam PF03454 MoeA C-terminal region (domain IV) 344 416 1.1E-19 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CU254_RS34135 e0bf2841c9b8354697cf7cc8d1dad67d 420 SUPERFAMILY SSF63867 339 416 1.83E-18 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CU254_RS34135 e0bf2841c9b8354697cf7cc8d1dad67d 420 SUPERFAMILY SSF63882 14 187 9.55E-46 T 28-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CU254_RS34135 e0bf2841c9b8354697cf7cc8d1dad67d 420 Pfam PF00994 Probable molybdopterin binding domain 192 329 1.4E-18 T 28-03-2018 IPR001453 MoaB/Mog domain CU254_RS34135 e0bf2841c9b8354697cf7cc8d1dad67d 420 Gene3D G3DSA:2.40.340.10 342 418 4.3E-22 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CU254_RS34135 e0bf2841c9b8354697cf7cc8d1dad67d 420 Pfam PF03453 MoeA N-terminal region (domain I and II) 16 178 1.5E-39 T 28-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CU254_RS34135 e0bf2841c9b8354697cf7cc8d1dad67d 420 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 188 326 5.3E-25 T 28-03-2018 IPR001453 MoaB/Mog domain CU254_RS34135 e0bf2841c9b8354697cf7cc8d1dad67d 420 Gene3D G3DSA:3.40.980.10 161 337 1.4E-42 T 28-03-2018 IPR001453 MoaB/Mog domain CU254_RS22285 ccc5844ad1d00e0f27efa5459eebf09d 295 SUPERFAMILY SSF46785 200 273 1.52E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS22285 ccc5844ad1d00e0f27efa5459eebf09d 295 Pfam PF04079 Segregation and condensation complex subunit ScpB 124 282 1.5E-48 T 28-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CU254_RS22285 ccc5844ad1d00e0f27efa5459eebf09d 295 SUPERFAMILY SSF46785 120 196 1.33E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS22285 ccc5844ad1d00e0f27efa5459eebf09d 295 Gene3D G3DSA:1.10.10.10 111 199 3.2E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS22285 ccc5844ad1d00e0f27efa5459eebf09d 295 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 122 283 1.8E-29 T 28-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CU254_RS22285 ccc5844ad1d00e0f27efa5459eebf09d 295 Gene3D G3DSA:1.10.10.10 200 290 1.4E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS22285 ccc5844ad1d00e0f27efa5459eebf09d 295 PIRSF PIRSF019345 111 295 6.7E-54 T 28-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CU254_RS22285 ccc5844ad1d00e0f27efa5459eebf09d 295 PIRSF PIRSF019345 11 91 1300.0 T 28-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CU254_RS17640 8d171c9cefd10f42a9bd63e08d801564 278 Pfam PF07859 alpha/beta hydrolase fold 69 185 6.2E-18 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CU254_RS17640 8d171c9cefd10f42a9bd63e08d801564 278 Gene3D G3DSA:3.40.50.1820 46 194 7.6E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS17640 8d171c9cefd10f42a9bd63e08d801564 278 SUPERFAMILY SSF53474 9 261 2.18E-45 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS17640 8d171c9cefd10f42a9bd63e08d801564 278 Gene3D G3DSA:3.40.50.1820 195 274 0.027 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS04515 12bbc9d2b5aca2fd2abef1512053cc63 991 SUPERFAMILY SSF81593 327 483 1.41E-37 T 28-03-2018 CU254_RS04515 12bbc9d2b5aca2fd2abef1512053cc63 991 Gene3D G3DSA:3.30.460.10 176 322 2.3E-47 T 28-03-2018 CU254_RS04515 12bbc9d2b5aca2fd2abef1512053cc63 991 Gene3D G3DSA:3.30.460.10 669 830 7.4E-55 T 28-03-2018 CU254_RS04515 12bbc9d2b5aca2fd2abef1512053cc63 991 Hamap MF_00802 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme [glnE]. 83 979 16.621 T 28-03-2018 IPR023057 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme GO:0008882 CU254_RS04515 12bbc9d2b5aca2fd2abef1512053cc63 991 Pfam PF08335 GlnD PII-uridylyltransferase 336 482 9.7E-37 T 28-03-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 CU254_RS04515 12bbc9d2b5aca2fd2abef1512053cc63 991 Pfam PF08335 GlnD PII-uridylyltransferase 845 988 1.5E-20 T 28-03-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 CU254_RS04515 12bbc9d2b5aca2fd2abef1512053cc63 991 SUPERFAMILY SSF81593 836 989 4.63E-36 T 28-03-2018 CU254_RS04515 12bbc9d2b5aca2fd2abef1512053cc63 991 Gene3D G3DSA:1.10.4050.10 561 668 1.7E-19 T 28-03-2018 CU254_RS04515 12bbc9d2b5aca2fd2abef1512053cc63 991 Gene3D G3DSA:1.10.4050.10 60 168 5.6E-20 T 28-03-2018 CU254_RS04515 12bbc9d2b5aca2fd2abef1512053cc63 991 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 87 314 1.3E-33 T 28-03-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 CU254_RS04515 12bbc9d2b5aca2fd2abef1512053cc63 991 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 587 822 4.1E-61 T 28-03-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 CU254_RS04515 12bbc9d2b5aca2fd2abef1512053cc63 991 Gene3D G3DSA:1.20.120.330 325 486 8.0E-50 T 28-03-2018 CU254_RS04515 12bbc9d2b5aca2fd2abef1512053cc63 991 Gene3D G3DSA:1.20.120.330 834 991 2.3E-46 T 28-03-2018 CU254_RS04515 12bbc9d2b5aca2fd2abef1512053cc63 991 SUPERFAMILY SSF81301 559 831 1.14E-68 T 28-03-2018 CU254_RS04515 12bbc9d2b5aca2fd2abef1512053cc63 991 SUPERFAMILY SSF81301 70 322 1.96E-54 T 28-03-2018 CU254_RS17110 b5742eec960e942d703ef476e2825945 228 Pfam PF13936 Helix-turn-helix domain 5 45 2.0E-12 T 28-03-2018 IPR025246 Transposase IS30-like HTH domain CU254_RS17110 b5742eec960e942d703ef476e2825945 228 SUPERFAMILY SSF46785 88 163 8.81E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS17110 b5742eec960e942d703ef476e2825945 228 Pfam PF12802 MarR family 101 158 2.9E-9 T 28-03-2018 CU254_RS17110 b5742eec960e942d703ef476e2825945 228 Gene3D G3DSA:1.10.10.60 3 44 3.6E-10 T 28-03-2018 CU254_RS17110 b5742eec960e942d703ef476e2825945 228 SMART SM00418 101 178 0.0026 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS17110 b5742eec960e942d703ef476e2825945 228 Gene3D G3DSA:1.10.10.10 45 226 1.7E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS30835 72f186cb52f8f5ab97939f35b0430968 486 SUPERFAMILY SSF51905 295 413 1.55E-56 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS30835 72f186cb52f8f5ab97939f35b0430968 486 SUPERFAMILY SSF51905 9 228 1.55E-56 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS30835 72f186cb52f8f5ab97939f35b0430968 486 Gene3D G3DSA:3.50.50.60 164 486 3.7E-56 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS30835 72f186cb52f8f5ab97939f35b0430968 486 Gene3D G3DSA:3.50.50.60 6 163 1.2E-33 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS30835 72f186cb52f8f5ab97939f35b0430968 486 Pfam PF00743 Flavin-binding monooxygenase-like 9 343 2.2E-19 T 28-03-2018 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 CU254_RS34980 d41bac641227382a3e943bd91a590bbb 193 Gene3D G3DSA:1.10.357.10 1 193 5.2E-36 T 28-03-2018 CU254_RS34980 d41bac641227382a3e943bd91a590bbb 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 52 2.1E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS34980 d41bac641227382a3e943bd91a590bbb 193 SUPERFAMILY SSF46689 3 71 7.18E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS08735 0d759d8dc254e1c6f2f4cc746f903e18 247 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 84 136 2.0E-17 T 28-03-2018 CU254_RS08735 0d759d8dc254e1c6f2f4cc746f903e18 247 Hamap MF_00013 Octanoyltransferase [lipB]. 14 221 34.292 T 28-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CU254_RS08735 0d759d8dc254e1c6f2f4cc746f903e18 247 PIRSF PIRSF016262 10 226 1.6E-60 T 28-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CU254_RS08735 0d759d8dc254e1c6f2f4cc746f903e18 247 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 80 95 - T 28-03-2018 IPR020605 Octanoyltransferase, conserved site GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 CU254_RS08735 0d759d8dc254e1c6f2f4cc746f903e18 247 Gene3D G3DSA:3.30.930.10 8 219 2.1E-69 T 28-03-2018 CU254_RS08735 0d759d8dc254e1c6f2f4cc746f903e18 247 Pfam PF03099 Biotin/lipoate A/B protein ligase family 70 173 1.5E-7 T 28-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CU254_RS08735 0d759d8dc254e1c6f2f4cc746f903e18 247 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 39 206 1.1E-38 T 28-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CU254_RS08735 0d759d8dc254e1c6f2f4cc746f903e18 247 SUPERFAMILY SSF55681 12 220 2.4E-65 T 28-03-2018 CU254_RS03190 be93d12fdbe9fe9077ad0a85f12bb138 589 SUPERFAMILY SSF51905 40 341 4.09E-38 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS03190 be93d12fdbe9fe9077ad0a85f12bb138 589 Gene3D G3DSA:3.50.50.60 348 433 4.9E-17 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS03190 be93d12fdbe9fe9077ad0a85f12bb138 589 Gene3D G3DSA:3.30.9.10 121 214 1.6E-17 T 28-03-2018 CU254_RS03190 be93d12fdbe9fe9077ad0a85f12bb138 589 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 419 543 6.4E-34 T 28-03-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CU254_RS03190 be93d12fdbe9fe9077ad0a85f12bb138 589 Gene3D G3DSA:3.30.9.10 215 347 8.2E-31 T 28-03-2018 CU254_RS03190 be93d12fdbe9fe9077ad0a85f12bb138 589 Gene3D G3DSA:3.50.50.60 6 105 4.1E-6 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS03190 be93d12fdbe9fe9077ad0a85f12bb138 589 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 71 83 4.9E-32 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CU254_RS03190 be93d12fdbe9fe9077ad0a85f12bb138 589 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 356 362 4.9E-32 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CU254_RS03190 be93d12fdbe9fe9077ad0a85f12bb138 589 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 117 129 4.9E-32 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CU254_RS03190 be93d12fdbe9fe9077ad0a85f12bb138 589 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 386 398 4.9E-32 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CU254_RS03190 be93d12fdbe9fe9077ad0a85f12bb138 589 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 42 54 4.9E-32 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CU254_RS03190 be93d12fdbe9fe9077ad0a85f12bb138 589 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 55 65 4.9E-32 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CU254_RS03190 be93d12fdbe9fe9077ad0a85f12bb138 589 Pfam PF01266 FAD dependent oxidoreductase 43 366 1.4E-52 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CU254_RS03190 be93d12fdbe9fe9077ad0a85f12bb138 589 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 47 64 - T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CU254_RS03190 be93d12fdbe9fe9077ad0a85f12bb138 589 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 391 401 - T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CU254_RS27305 6e7d3bb5c9bae2d7105881bb51998da2 922 Gene3D G3DSA:3.30.70.100 871 913 0.053 T 28-03-2018 CU254_RS27305 6e7d3bb5c9bae2d7105881bb51998da2 922 SUPERFAMILY SSF46894 4 91 5.1E-12 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS27305 6e7d3bb5c9bae2d7105881bb51998da2 922 Pfam PF00486 Transcriptional regulatory protein, C terminal 26 89 8.8E-10 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS27305 6e7d3bb5c9bae2d7105881bb51998da2 922 Gene3D G3DSA:1.25.40.10 96 261 2.1E-18 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS27305 6e7d3bb5c9bae2d7105881bb51998da2 922 Pfam PF03704 Bacterial transcriptional activator domain 99 240 9.7E-28 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CU254_RS27305 6e7d3bb5c9bae2d7105881bb51998da2 922 Gene3D G3DSA:1.10.10.10 1 94 3.5E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS27305 6e7d3bb5c9bae2d7105881bb51998da2 922 Gene3D G3DSA:3.40.50.300 262 415 2.3E-15 T 28-03-2018 CU254_RS27305 6e7d3bb5c9bae2d7105881bb51998da2 922 SUPERFAMILY SSF52540 257 519 1.45E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS27305 6e7d3bb5c9bae2d7105881bb51998da2 922 Gene3D G3DSA:1.25.40.10 694 812 1.1E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS27305 6e7d3bb5c9bae2d7105881bb51998da2 922 Pfam PF00931 NB-ARC domain 280 520 8.1E-10 T 28-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 CU254_RS27305 6e7d3bb5c9bae2d7105881bb51998da2 922 Gene3D G3DSA:1.10.10.10 492 589 7.2E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS27305 6e7d3bb5c9bae2d7105881bb51998da2 922 Gene3D G3DSA:1.10.150.200 813 870 6.7E-13 T 28-03-2018 CU254_RS27305 6e7d3bb5c9bae2d7105881bb51998da2 922 SUPERFAMILY SSF46785 516 579 2.1E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS27305 6e7d3bb5c9bae2d7105881bb51998da2 922 SUPERFAMILY SSF48452 96 265 1.29E-23 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS27305 6e7d3bb5c9bae2d7105881bb51998da2 922 SMART SM00028 864 897 21.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS27305 6e7d3bb5c9bae2d7105881bb51998da2 922 SMART SM00028 824 857 0.0069 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS27305 6e7d3bb5c9bae2d7105881bb51998da2 922 SMART SM00028 785 818 0.04 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS27305 6e7d3bb5c9bae2d7105881bb51998da2 922 SMART SM00028 745 778 61.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS27305 6e7d3bb5c9bae2d7105881bb51998da2 922 PRINTS PR00364 Disease resistance protein signature 290 305 1.1E-7 T 28-03-2018 CU254_RS27305 6e7d3bb5c9bae2d7105881bb51998da2 922 PRINTS PR00364 Disease resistance protein signature 369 383 1.1E-7 T 28-03-2018 CU254_RS27305 6e7d3bb5c9bae2d7105881bb51998da2 922 PRINTS PR00364 Disease resistance protein signature 457 471 1.1E-7 T 28-03-2018 CU254_RS27305 6e7d3bb5c9bae2d7105881bb51998da2 922 SMART SM01043 99 240 5.2E-35 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CU254_RS27305 6e7d3bb5c9bae2d7105881bb51998da2 922 SMART SM00862 17 91 2.5E-10 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS27305 6e7d3bb5c9bae2d7105881bb51998da2 922 SUPERFAMILY SSF48452 707 910 3.37E-24 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS27305 6e7d3bb5c9bae2d7105881bb51998da2 922 Pfam PF13424 Tetratricopeptide repeat 785 856 6.0E-13 T 28-03-2018 CU254_RS38450 16550ae0d8861b16014383257e24fa57 192 SUPERFAMILY SSF52141 17 176 2.7E-43 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CU254_RS38450 16550ae0d8861b16014383257e24fa57 192 Pfam PF03167 Uracil DNA glycosylase superfamily 20 173 1.2E-25 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CU254_RS38450 16550ae0d8861b16014383257e24fa57 192 SMART SM00986 19 185 1.8E-10 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CU254_RS38450 16550ae0d8861b16014383257e24fa57 192 Gene3D G3DSA:3.40.470.10 5 183 7.9E-50 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CU254_RS38450 16550ae0d8861b16014383257e24fa57 192 SMART SM00987 19 185 1.8E-10 T 28-03-2018 CU254_RS38220 3b9051e1c4234d5e84da5c306d88bde0 187 Pfam PF00156 Phosphoribosyl transferase domain 115 166 5.0E-10 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CU254_RS38220 3b9051e1c4234d5e84da5c306d88bde0 187 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 20 183 2.1E-33 T 28-03-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CU254_RS38220 3b9051e1c4234d5e84da5c306d88bde0 187 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 187 23.238 T 28-03-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CU254_RS38220 3b9051e1c4234d5e84da5c306d88bde0 187 Gene3D G3DSA:3.40.50.2020 6 187 3.8E-30 T 28-03-2018 CU254_RS38220 3b9051e1c4234d5e84da5c306d88bde0 187 SUPERFAMILY SSF53271 15 184 5.64E-31 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CU254_RS20465 0e1317f3612ed2f0f0cbf13243817f38 558 SUPERFAMILY SSF52540 329 555 5.03E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS20465 0e1317f3612ed2f0f0cbf13243817f38 558 SUPERFAMILY SSF90123 10 317 1.7E-52 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CU254_RS20465 0e1317f3612ed2f0f0cbf13243817f38 558 Gene3D G3DSA:3.40.50.300 333 556 1.5E-41 T 28-03-2018 CU254_RS20465 0e1317f3612ed2f0f0cbf13243817f38 558 Gene3D G3DSA:1.20.1560.10 1 325 6.3E-49 T 28-03-2018 CU254_RS20465 0e1317f3612ed2f0f0cbf13243817f38 558 ProSitePatterns PS00211 ABC transporters family signature. 461 475 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS20465 0e1317f3612ed2f0f0cbf13243817f38 558 Pfam PF00664 ABC transporter transmembrane region 21 289 6.2E-26 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CU254_RS20465 0e1317f3612ed2f0f0cbf13243817f38 558 Pfam PF00005 ABC transporter 344 488 1.5E-15 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS19185 e68bfaa31a6a9533a8dac4e7566681e7 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 62 2.9E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS19185 e68bfaa31a6a9533a8dac4e7566681e7 296 SUPERFAMILY SSF53850 94 293 2.48E-27 T 28-03-2018 CU254_RS19185 e68bfaa31a6a9533a8dac4e7566681e7 296 SUPERFAMILY SSF46785 6 84 6.2E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS19185 e68bfaa31a6a9533a8dac4e7566681e7 296 Gene3D G3DSA:3.40.190.10 179 269 1.3E-21 T 28-03-2018 CU254_RS19185 e68bfaa31a6a9533a8dac4e7566681e7 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.3E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS19185 e68bfaa31a6a9533a8dac4e7566681e7 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.3E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS19185 e68bfaa31a6a9533a8dac4e7566681e7 296 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.3E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS19185 e68bfaa31a6a9533a8dac4e7566681e7 296 Gene3D G3DSA:1.10.10.10 1 82 1.5E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS19185 e68bfaa31a6a9533a8dac4e7566681e7 296 Gene3D G3DSA:3.40.190.10 89 178 1.3E-15 T 28-03-2018 CU254_RS19185 e68bfaa31a6a9533a8dac4e7566681e7 296 Pfam PF03466 LysR substrate binding domain 94 291 2.6E-26 T 28-03-2018 IPR005119 LysR, substrate-binding CU254_RS19950 a1f3feb5949ce81874df2035ea2dfb9a 253 SMART SM00650 22 182 2.2E-51 T 28-03-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 CU254_RS19950 a1f3feb5949ce81874df2035ea2dfb9a 253 SUPERFAMILY SSF53335 14 251 1.71E-35 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS19950 a1f3feb5949ce81874df2035ea2dfb9a 253 Gene3D G3DSA:3.40.50.150 2 197 3.1E-26 T 28-03-2018 CU254_RS19950 a1f3feb5949ce81874df2035ea2dfb9a 253 Pfam PF00398 Ribosomal RNA adenine dimethylase 8 250 6.4E-29 T 28-03-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm CU254_RS12400 bbfef3d5e4ffb373e0e3babdbc53e212 240 SUPERFAMILY SSF88713 2 236 2.08E-78 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CU254_RS12400 bbfef3d5e4ffb373e0e3babdbc53e212 240 Pfam PF03746 LamB/YcsF family 2 235 1.3E-88 T 28-03-2018 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF CU254_RS12400 bbfef3d5e4ffb373e0e3babdbc53e212 240 Gene3D G3DSA:3.20.20.370 1 238 4.6E-91 T 28-03-2018 CU254_RS40220 4f76493b2cb93ac979af4e6f69692e06 394 Pfam PF00534 Glycosyl transferases group 1 207 365 6.0E-21 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CU254_RS40220 4f76493b2cb93ac979af4e6f69692e06 394 SUPERFAMILY SSF53756 2 389 4.32E-57 T 28-03-2018 CU254_RS40220 4f76493b2cb93ac979af4e6f69692e06 394 Gene3D G3DSA:3.40.50.2000 203 374 9.0E-35 T 28-03-2018 CU254_RS40220 4f76493b2cb93ac979af4e6f69692e06 394 Pfam PF13439 Glycosyltransferase Family 4 14 150 4.6E-15 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CU254_RS40220 4f76493b2cb93ac979af4e6f69692e06 394 Gene3D G3DSA:3.40.50.2000 1 202 2.6E-16 T 28-03-2018 CU254_RS06300 30a8b4d4a7d83c0985398fc37056e0fb 358 TIGRFAM TIGR02160 PA_CoA_Oxy5: phenylacetate-CoA oxygenase/reductase, PaaK subunit 11 357 3.9E-149 T 28-03-2018 IPR011884 Phenylacetate-CoA oxygenase/reductase, PaaK subunit GO:0010124 CU254_RS06300 30a8b4d4a7d83c0985398fc37056e0fb 358 Gene3D G3DSA:3.10.20.30 241 358 8.7E-29 T 28-03-2018 IPR012675 Beta-grasp domain CU254_RS06300 30a8b4d4a7d83c0985398fc37056e0fb 358 Pfam PF00970 Oxidoreductase FAD-binding domain 14 109 1.8E-11 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CU254_RS06300 30a8b4d4a7d83c0985398fc37056e0fb 358 Pfam PF00175 Oxidoreductase NAD-binding domain 121 229 2.3E-18 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CU254_RS06300 30a8b4d4a7d83c0985398fc37056e0fb 358 SUPERFAMILY SSF52343 100 245 1.02E-35 T 28-03-2018 CU254_RS06300 30a8b4d4a7d83c0985398fc37056e0fb 358 Gene3D G3DSA:3.40.50.80 99 240 1.8E-30 T 28-03-2018 CU254_RS06300 30a8b4d4a7d83c0985398fc37056e0fb 358 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 276 347 5.0E-13 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CU254_RS06300 30a8b4d4a7d83c0985398fc37056e0fb 358 SUPERFAMILY SSF54292 238 353 3.93E-26 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CU254_RS06300 30a8b4d4a7d83c0985398fc37056e0fb 358 Gene3D G3DSA:2.40.30.10 2 98 2.0E-18 T 28-03-2018 CU254_RS06300 30a8b4d4a7d83c0985398fc37056e0fb 358 PRINTS PR00409 Phthalate dioxygenase reductase family signature 120 139 5.6E-6 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CU254_RS06300 30a8b4d4a7d83c0985398fc37056e0fb 358 PRINTS PR00409 Phthalate dioxygenase reductase family signature 62 76 5.6E-6 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CU254_RS06300 30a8b4d4a7d83c0985398fc37056e0fb 358 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 62 69 2.5E-5 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CU254_RS06300 30a8b4d4a7d83c0985398fc37056e0fb 358 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 120 139 2.5E-5 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CU254_RS06300 30a8b4d4a7d83c0985398fc37056e0fb 358 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 144 153 2.5E-5 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CU254_RS06300 30a8b4d4a7d83c0985398fc37056e0fb 358 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 156 167 2.5E-5 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CU254_RS06300 30a8b4d4a7d83c0985398fc37056e0fb 358 SUPERFAMILY SSF63380 8 111 1.09E-23 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CU254_RS06300 30a8b4d4a7d83c0985398fc37056e0fb 358 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 305 313 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CU254_RS33700 f08165601297da08d9f768fffc6220b8 374 SUPERFAMILY SSF55874 249 369 1.49E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS33700 f08165601297da08d9f768fffc6220b8 374 Gene3D G3DSA:3.30.565.10 155 369 2.2E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS33700 f08165601297da08d9f768fffc6220b8 374 Pfam PF07730 Histidine kinase 175 238 1.5E-17 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CU254_RS04910 655ef74267716ef07e132bf2503f3124 513 Gene3D G3DSA:2.30.38.10 320 409 2.5E-15 T 28-03-2018 CU254_RS04910 655ef74267716ef07e132bf2503f3124 513 ProSitePatterns PS00455 Putative AMP-binding domain signature. 153 164 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS04910 655ef74267716ef07e132bf2503f3124 513 Gene3D G3DSA:3.30.300.30 421 508 0.0016 T 28-03-2018 CU254_RS04910 655ef74267716ef07e132bf2503f3124 513 SUPERFAMILY SSF56801 19 503 4.32E-65 T 28-03-2018 CU254_RS04910 655ef74267716ef07e132bf2503f3124 513 Gene3D G3DSA:3.40.50.980 22 157 9.4E-25 T 28-03-2018 CU254_RS04910 655ef74267716ef07e132bf2503f3124 513 Pfam PF00501 AMP-binding enzyme 24 410 1.3E-53 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS04910 655ef74267716ef07e132bf2503f3124 513 Gene3D G3DSA:3.40.50.980 158 319 1.9E-15 T 28-03-2018 CU254_RS24895 32764f5ceb6ff54fa474aad96ca3333f 157 SUPERFAMILY SSF47413 21 62 3.56E-6 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS24895 32764f5ceb6ff54fa474aad96ca3333f 157 Gene3D G3DSA:1.10.260.40 11 151 2.7E-7 T 28-03-2018 CU254_RS19800 9dd2a67dcdd9f593217f65ffd2fdd7e8 303 SUPERFAMILY SSF50475 173 260 6.62E-11 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS19800 9dd2a67dcdd9f593217f65ffd2fdd7e8 303 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 173 257 4.0E-15 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CU254_RS19800 9dd2a67dcdd9f593217f65ffd2fdd7e8 303 Gene3D G3DSA:2.30.110.10 164 301 1.5E-19 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS19800 9dd2a67dcdd9f593217f65ffd2fdd7e8 303 Gene3D G3DSA:2.30.110.10 28 163 4.0E-6 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS31790 ea270b647655b7f78b3b2ff37ff9b899 88 Gene3D G3DSA:2.160.20.70 1 82 1.2E-4 T 28-03-2018 CU254_RS23535 ab3eca0b1394d6218301711fce861812 444 Pfam PF00083 Sugar (and other) transporter 18 227 5.2E-22 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CU254_RS23535 ab3eca0b1394d6218301711fce861812 444 Pfam PF07690 Major Facilitator Superfamily 273 418 3.1E-10 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS23535 ab3eca0b1394d6218301711fce861812 444 Gene3D G3DSA:1.20.1250.20 236 431 2.5E-21 T 28-03-2018 CU254_RS23535 ab3eca0b1394d6218301711fce861812 444 Gene3D G3DSA:1.20.1250.20 7 227 3.0E-22 T 28-03-2018 CU254_RS23535 ab3eca0b1394d6218301711fce861812 444 SUPERFAMILY SSF103473 12 423 2.88E-60 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS04840 34af665de805a805084c3df9334a4385 367 Hamap MF_00094 Peptide chain release factor 2 [prfB]. 1 362 37.749 T 28-03-2018 IPR020853 Peptide chain release factor 2, bacterial GO:0005737|GO:0006415|GO:0016149 CU254_RS04840 34af665de805a805084c3df9334a4385 367 Gene3D G3DSA:1.20.58.410 2 114 2.6E-27 T 28-03-2018 CU254_RS04840 34af665de805a805084c3df9334a4385 367 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 243 259 - T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CU254_RS04840 34af665de805a805084c3df9334a4385 367 Gene3D G3DSA:3.30.160.20 224 306 2.1E-33 T 28-03-2018 CU254_RS04840 34af665de805a805084c3df9334a4385 367 SMART SM00937 83 193 1.1E-46 T 28-03-2018 IPR005139 Peptide chain release factor GO:0006415 CU254_RS04840 34af665de805a805084c3df9334a4385 367 Pfam PF00472 RF-1 domain 227 334 7.7E-38 T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CU254_RS04840 34af665de805a805084c3df9334a4385 367 Pfam PF03462 PCRF domain 29 218 4.0E-55 T 28-03-2018 IPR005139 Peptide chain release factor GO:0006415 CU254_RS04840 34af665de805a805084c3df9334a4385 367 SUPERFAMILY SSF75620 28 362 6.28E-121 T 28-03-2018 CU254_RS04840 34af665de805a805084c3df9334a4385 367 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 4 361 7.0E-156 T 28-03-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 CU254_RS13400 e81050ff1884e40b45c4e9644f12c2be 164 SUPERFAMILY SSF52402 30 164 1.51E-25 T 28-03-2018 CU254_RS13400 e81050ff1884e40b45c4e9644f12c2be 164 PRINTS PR01438 Universal stress protein signature 142 164 1.0E-5 T 28-03-2018 IPR006015 Universal stress protein A CU254_RS13400 e81050ff1884e40b45c4e9644f12c2be 164 PRINTS PR01438 Universal stress protein signature 27 45 1.0E-5 T 28-03-2018 IPR006015 Universal stress protein A CU254_RS13400 e81050ff1884e40b45c4e9644f12c2be 164 Pfam PF00582 Universal stress protein family 28 164 1.4E-24 T 28-03-2018 IPR006016 UspA GO:0006950 CU254_RS13400 e81050ff1884e40b45c4e9644f12c2be 164 Gene3D G3DSA:3.40.50.620 18 164 1.3E-27 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS04210 54602aaaa879702da859ba60a7640afe 169 Gene3D G3DSA:3.30.530.20 1 169 1.0E-25 T 28-03-2018 IPR023393 START-like domain CU254_RS04210 54602aaaa879702da859ba60a7640afe 169 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 15 162 4.1E-21 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CU254_RS04210 54602aaaa879702da859ba60a7640afe 169 SUPERFAMILY SSF55961 4 164 2.05E-27 T 28-03-2018 CU254_RS35605 fc38ef362c92d1016fc4fbb17ea86efb 917 Gene3D G3DSA:1.10.10.10 1 100 6.7E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS35605 fc38ef362c92d1016fc4fbb17ea86efb 917 Pfam PF00486 Transcriptional regulatory protein, C terminal 32 97 2.3E-8 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS35605 fc38ef362c92d1016fc4fbb17ea86efb 917 Pfam PF03704 Bacterial transcriptional activator domain 105 241 3.7E-29 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CU254_RS35605 fc38ef362c92d1016fc4fbb17ea86efb 917 SUPERFAMILY SSF52540 262 520 1.03E-21 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS35605 fc38ef362c92d1016fc4fbb17ea86efb 917 Pfam PF00931 NB-ARC domain 279 529 6.4E-9 T 28-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 CU254_RS35605 fc38ef362c92d1016fc4fbb17ea86efb 917 Gene3D G3DSA:1.25.40.10 101 256 7.6E-19 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS35605 fc38ef362c92d1016fc4fbb17ea86efb 917 SMART SM00862 20 97 1.8E-7 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS35605 fc38ef362c92d1016fc4fbb17ea86efb 917 Gene3D G3DSA:3.40.50.300 257 418 3.8E-13 T 28-03-2018 CU254_RS35605 fc38ef362c92d1016fc4fbb17ea86efb 917 SUPERFAMILY SSF48452 100 265 4.07E-27 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS35605 fc38ef362c92d1016fc4fbb17ea86efb 917 SMART SM00028 746 779 47.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS35605 fc38ef362c92d1016fc4fbb17ea86efb 917 SMART SM00028 866 899 96.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS35605 fc38ef362c92d1016fc4fbb17ea86efb 917 SMART SM00028 826 859 5.2 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS35605 fc38ef362c92d1016fc4fbb17ea86efb 917 SMART SM00028 786 819 110.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS35605 fc38ef362c92d1016fc4fbb17ea86efb 917 PRINTS PR00364 Disease resistance protein signature 368 382 7.5E-8 T 28-03-2018 CU254_RS35605 fc38ef362c92d1016fc4fbb17ea86efb 917 PRINTS PR00364 Disease resistance protein signature 452 466 7.5E-8 T 28-03-2018 CU254_RS35605 fc38ef362c92d1016fc4fbb17ea86efb 917 PRINTS PR00364 Disease resistance protein signature 289 304 7.5E-8 T 28-03-2018 CU254_RS35605 fc38ef362c92d1016fc4fbb17ea86efb 917 SUPERFAMILY SSF46894 8 97 2.1E-12 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS35605 fc38ef362c92d1016fc4fbb17ea86efb 917 SMART SM01043 104 241 5.5E-32 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CU254_RS35605 fc38ef362c92d1016fc4fbb17ea86efb 917 SUPERFAMILY SSF48452 746 901 1.0E-19 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS35605 fc38ef362c92d1016fc4fbb17ea86efb 917 Gene3D G3DSA:1.25.40.10 539 914 8.8E-24 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS35605 fc38ef362c92d1016fc4fbb17ea86efb 917 Pfam PF13424 Tetratricopeptide repeat 787 856 5.5E-11 T 28-03-2018 CU254_RS00070 49bac4c8fc14bef6de82d05602c57a0f 224 Pfam PF00196 Bacterial regulatory proteins, luxR family 159 214 4.5E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS00070 49bac4c8fc14bef6de82d05602c57a0f 224 Pfam PF00072 Response regulator receiver domain 7 121 8.5E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS00070 49bac4c8fc14bef6de82d05602c57a0f 224 ProSitePatterns PS00622 LuxR-type HTH domain signature. 174 201 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS00070 49bac4c8fc14bef6de82d05602c57a0f 224 SUPERFAMILY SSF52172 4 138 2.28E-31 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS00070 49bac4c8fc14bef6de82d05602c57a0f 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 174 3.2E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS00070 49bac4c8fc14bef6de82d05602c57a0f 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 174 190 3.2E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS00070 49bac4c8fc14bef6de82d05602c57a0f 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 190 202 3.2E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS00070 49bac4c8fc14bef6de82d05602c57a0f 224 SMART SM00448 5 120 3.0E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS00070 49bac4c8fc14bef6de82d05602c57a0f 224 SUPERFAMILY SSF46894 147 221 1.05E-23 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS00070 49bac4c8fc14bef6de82d05602c57a0f 224 Gene3D G3DSA:3.40.50.2300 4 138 8.0E-37 T 28-03-2018 CU254_RS00070 49bac4c8fc14bef6de82d05602c57a0f 224 SMART SM00421 157 214 1.7E-26 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS00070 49bac4c8fc14bef6de82d05602c57a0f 224 Gene3D G3DSA:1.10.10.10 139 219 2.5E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS09390 4a3dce1859c678957de8ee61ba6375a0 1513 Pfam PF00310 Glutamine amidotransferases class-II 22 438 1.2E-174 T 28-03-2018 IPR017932 Glutamine amidotransferase type 2 domain CU254_RS09390 4a3dce1859c678957de8ee61ba6375a0 1513 Gene3D G3DSA:2.160.20.60 1237 1507 1.3E-111 T 28-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 CU254_RS09390 4a3dce1859c678957de8ee61ba6375a0 1513 SUPERFAMILY SSF51395 453 1216 2.16E-258 T 28-03-2018 CU254_RS09390 4a3dce1859c678957de8ee61ba6375a0 1513 Gene3D G3DSA:3.20.20.70 448 797 3.1E-99 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS09390 4a3dce1859c678957de8ee61ba6375a0 1513 Pfam PF04898 Glutamate synthase central domain 465 752 3.6E-110 T 28-03-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 CU254_RS09390 4a3dce1859c678957de8ee61ba6375a0 1513 Gene3D G3DSA:3.60.20.10 22 447 3.7E-163 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CU254_RS09390 4a3dce1859c678957de8ee61ba6375a0 1513 Pfam PF01493 GXGXG motif 1262 1437 1.2E-77 T 28-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 CU254_RS09390 4a3dce1859c678957de8ee61ba6375a0 1513 Pfam PF01645 Conserved region in glutamate synthase 817 1181 3.0E-151 T 28-03-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 CU254_RS09390 4a3dce1859c678957de8ee61ba6375a0 1513 SUPERFAMILY SSF69336 1231 1491 1.14E-89 T 28-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 CU254_RS09390 4a3dce1859c678957de8ee61ba6375a0 1513 SUPERFAMILY SSF56235 22 440 4.05E-145 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CU254_RS09390 4a3dce1859c678957de8ee61ba6375a0 1513 Gene3D G3DSA:3.20.20.70 798 1234 1.7E-152 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS31420 4244eb5f18b964ba4eb2b0295271e067 198 SMART SM00903 21 175 4.9E-17 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CU254_RS31420 4244eb5f18b964ba4eb2b0295271e067 198 Pfam PF01613 Flavin reductase like domain 24 160 6.7E-22 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CU254_RS31420 4244eb5f18b964ba4eb2b0295271e067 198 Gene3D G3DSA:2.30.110.10 11 183 3.6E-47 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS31420 4244eb5f18b964ba4eb2b0295271e067 198 SUPERFAMILY SSF50475 4 188 1.08E-46 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS18995 39ec2d2bdf858b3c6e25caec109e0b4e 466 SUPERFAMILY SSF103473 84 453 6.67E-37 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS18995 39ec2d2bdf858b3c6e25caec109e0b4e 466 Pfam PF11700 Vacuole effluxer Atg22 like 9 458 2.3E-86 T 28-03-2018 IPR024671 Autophagy-related protein 22-like CU254_RS18995 39ec2d2bdf858b3c6e25caec109e0b4e 466 Gene3D G3DSA:1.20.1250.20 14 245 2.3E-16 T 28-03-2018 CU254_RS18995 39ec2d2bdf858b3c6e25caec109e0b4e 466 Gene3D G3DSA:1.20.1250.20 257 455 1.9E-21 T 28-03-2018 CU254_RS24540 3574bbbbdeb80698cfe1f197baa1e050 412 PIRSF PIRSF003085 7 412 1.0E-110 T 28-03-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 CU254_RS24540 3574bbbbdeb80698cfe1f197baa1e050 412 SUPERFAMILY SSF53335 135 397 3.8E-74 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS24540 3574bbbbdeb80698cfe1f197baa1e050 412 Gene3D G3DSA:3.40.50.150 123 396 8.9E-64 T 28-03-2018 CU254_RS24540 3574bbbbdeb80698cfe1f197baa1e050 412 Pfam PF02353 Mycolic acid cyclopropane synthetase 127 392 2.9E-78 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS27810 11edd33ab45c04fbd58a22d837aa14a7 356 SUPERFAMILY SSF53822 12 349 1.21E-66 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CU254_RS27810 11edd33ab45c04fbd58a22d837aa14a7 356 Gene3D G3DSA:3.40.50.2300 257 340 0.087 T 28-03-2018 CU254_RS27810 11edd33ab45c04fbd58a22d837aa14a7 356 Pfam PF13458 Periplasmic binding protein 13 334 1.4E-66 T 28-03-2018 IPR028081 Leucine-binding protein domain CU254_RS27810 11edd33ab45c04fbd58a22d837aa14a7 356 Gene3D G3DSA:3.40.50.2300 127 256 2.4E-19 T 28-03-2018 CU254_RS27810 11edd33ab45c04fbd58a22d837aa14a7 356 Gene3D G3DSA:3.40.50.2300 9 123 2.8E-14 T 28-03-2018 CU254_RS29185 2773d8b49fad6531e19aeb328e513cde 461 Pfam PF00067 Cytochrome P450 7 446 3.9E-82 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS29185 2773d8b49fad6531e19aeb328e513cde 461 PRINTS PR00463 E-class P450 group I signature 273 299 1.4E-19 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS29185 2773d8b49fad6531e19aeb328e513cde 461 PRINTS PR00463 E-class P450 group I signature 392 402 1.4E-19 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS29185 2773d8b49fad6531e19aeb328e513cde 461 PRINTS PR00463 E-class P450 group I signature 253 270 1.4E-19 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS29185 2773d8b49fad6531e19aeb328e513cde 461 PRINTS PR00463 E-class P450 group I signature 35 54 1.4E-19 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS29185 2773d8b49fad6531e19aeb328e513cde 461 PRINTS PR00463 E-class P450 group I signature 402 425 1.4E-19 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS29185 2773d8b49fad6531e19aeb328e513cde 461 PRINTS PR00385 P450 superfamily signature 264 281 1.3E-11 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS29185 2773d8b49fad6531e19aeb328e513cde 461 PRINTS PR00385 P450 superfamily signature 316 327 1.3E-11 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS29185 2773d8b49fad6531e19aeb328e513cde 461 PRINTS PR00385 P450 superfamily signature 393 402 1.3E-11 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS29185 2773d8b49fad6531e19aeb328e513cde 461 PRINTS PR00385 P450 superfamily signature 402 413 1.3E-11 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS29185 2773d8b49fad6531e19aeb328e513cde 461 Gene3D G3DSA:1.10.630.10 4 460 1.2E-114 T 28-03-2018 CU254_RS29185 2773d8b49fad6531e19aeb328e513cde 461 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 395 404 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CU254_RS29185 2773d8b49fad6531e19aeb328e513cde 461 SUPERFAMILY SSF48264 6 453 2.23E-108 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS38730 56c63e1e9963216f30b4b27fe8306589 606 ProSitePatterns PS00505 Phosphoenolpyruvate carboxykinase (GTP) signature. 271 279 - T 28-03-2018 IPR018091 Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site GO:0004613 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 CU254_RS38730 56c63e1e9963216f30b4b27fe8306589 606 Gene3D G3DSA:3.90.228.20 327 606 5.1E-126 T 28-03-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CU254_RS38730 56c63e1e9963216f30b4b27fe8306589 606 Gene3D G3DSA:3.90.228.20 247 318 9.1E-21 T 28-03-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CU254_RS38730 56c63e1e9963216f30b4b27fe8306589 606 Hamap MF_00452 Phosphoenolpyruvate carboxykinase [GTP] [pckG]. 10 606 49.736 T 28-03-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 CU254_RS38730 56c63e1e9963216f30b4b27fe8306589 606 Gene3D G3DSA:3.40.449.10 6 246 5.9E-108 T 28-03-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CU254_RS38730 56c63e1e9963216f30b4b27fe8306589 606 Pfam PF00821 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain 247 605 4.9E-172 T 28-03-2018 IPR035077 Phosphoenolpyruvate carboxykinase, GTP-utilising, C-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 CU254_RS38730 56c63e1e9963216f30b4b27fe8306589 606 SUPERFAMILY SSF53795 247 605 6.87E-158 T 28-03-2018 CU254_RS38730 56c63e1e9963216f30b4b27fe8306589 606 Pfam PF17297 Phosphoenolpyruvate carboxykinase N-terminal domain 22 243 7.6E-98 T 28-03-2018 IPR035078 Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 CU254_RS38730 56c63e1e9963216f30b4b27fe8306589 606 PIRSF PIRSF001348 2 606 1.1E-281 T 28-03-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 CU254_RS38730 56c63e1e9963216f30b4b27fe8306589 606 SUPERFAMILY SSF68923 12 246 1.31E-92 T 28-03-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CU254_RS25325 39179e35cb5e7812ac9e238f293680c8 298 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 59 172 3.5E-18 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CU254_RS25325 39179e35cb5e7812ac9e238f293680c8 298 SUPERFAMILY SSF161098 58 278 3.53E-46 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS25325 39179e35cb5e7812ac9e238f293680c8 298 Gene3D G3DSA:1.10.3720.10 22 283 3.2E-52 T 28-03-2018 CU254_RS25325 39179e35cb5e7812ac9e238f293680c8 298 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 78 278 1.1E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS21645 d7899eaf04789efae47c606d589b877a 678 SUPERFAMILY SSF55186 70 264 9.29E-53 T 28-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 CU254_RS21645 d7899eaf04789efae47c606d589b877a 678 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 72 662 32.667 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CU254_RS21645 d7899eaf04789efae47c606d589b877a 678 Pfam PF03129 Anticodon binding domain 571 658 5.3E-17 T 28-03-2018 IPR004154 Anticodon-binding CU254_RS21645 d7899eaf04789efae47c606d589b877a 678 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 78 657 2.6E-190 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CU254_RS21645 d7899eaf04789efae47c606d589b877a 678 Gene3D G3DSA:3.30.980.10 199 246 6.4E-15 T 28-03-2018 CU254_RS21645 d7899eaf04789efae47c606d589b877a 678 Gene3D G3DSA:3.30.54.20 150 198 9.1E-17 T 28-03-2018 CU254_RS21645 d7899eaf04789efae47c606d589b877a 678 Gene3D G3DSA:3.30.930.10 247 559 6.0E-100 T 28-03-2018 CU254_RS21645 d7899eaf04789efae47c606d589b877a 678 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 197 243 9.4E-14 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CU254_RS21645 d7899eaf04789efae47c606d589b877a 678 SUPERFAMILY SSF55681 267 553 2.39E-88 T 28-03-2018 CU254_RS21645 d7899eaf04789efae47c606d589b877a 678 Gene3D G3DSA:3.40.50.800 560 669 2.2E-22 T 28-03-2018 IPR004154 Anticodon-binding CU254_RS21645 d7899eaf04789efae47c606d589b877a 678 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 349 557 4.1E-36 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CU254_RS21645 d7899eaf04789efae47c606d589b877a 678 PRINTS PR01047 Threonyl-tRNA synthetase signature 492 520 1.8E-47 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CU254_RS21645 d7899eaf04789efae47c606d589b877a 678 PRINTS PR01047 Threonyl-tRNA synthetase signature 535 548 1.8E-47 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CU254_RS21645 d7899eaf04789efae47c606d589b877a 678 PRINTS PR01047 Threonyl-tRNA synthetase signature 355 383 1.8E-47 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CU254_RS21645 d7899eaf04789efae47c606d589b877a 678 PRINTS PR01047 Threonyl-tRNA synthetase signature 388 411 1.8E-47 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CU254_RS21645 d7899eaf04789efae47c606d589b877a 678 PRINTS PR01047 Threonyl-tRNA synthetase signature 562 574 1.8E-47 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CU254_RS21645 d7899eaf04789efae47c606d589b877a 678 SMART SM00863 187 243 6.7E-22 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CU254_RS21645 d7899eaf04789efae47c606d589b877a 678 Gene3D G3DSA:3.30.980.10 74 149 4.6E-17 T 28-03-2018 CU254_RS21645 d7899eaf04789efae47c606d589b877a 678 SUPERFAMILY SSF52954 557 663 1.81E-27 T 28-03-2018 IPR004154 Anticodon-binding CU254_RS07195 82d917da2eec4c42ef862f25e6030cdb 1125 Pfam PF00682 HMGL-like 527 796 7.3E-30 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CU254_RS07195 82d917da2eec4c42ef862f25e6030cdb 1125 Gene3D G3DSA:3.30.1490.20 134 203 1.9E-19 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CU254_RS07195 82d917da2eec4c42ef862f25e6030cdb 1125 SUPERFAMILY SSF56059 84 362 8.49E-71 T 28-03-2018 CU254_RS07195 82d917da2eec4c42ef862f25e6030cdb 1125 TIGRFAM TIGR01235 pyruv_carbox: pyruvate carboxylase 4 1125 0.0 T 28-03-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 CU254_RS07195 82d917da2eec4c42ef862f25e6030cdb 1125 Gene3D G3DSA:3.40.50.20 1 132 7.1E-47 T 28-03-2018 CU254_RS07195 82d917da2eec4c42ef862f25e6030cdb 1125 Pfam PF00364 Biotin-requiring enzyme 1066 1124 1.4E-12 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CU254_RS07195 82d917da2eec4c42ef862f25e6030cdb 1125 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CU254_RS07195 82d917da2eec4c42ef862f25e6030cdb 1125 Gene3D G3DSA:2.40.50.100 1055 1125 2.9E-15 T 28-03-2018 CU254_RS07195 82d917da2eec4c42ef862f25e6030cdb 1125 SMART SM00878 339 446 4.5E-54 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CU254_RS07195 82d917da2eec4c42ef862f25e6030cdb 1125 SUPERFAMILY SSF51230 1048 1125 3.14E-15 T 28-03-2018 IPR011053 Single hybrid motif CU254_RS07195 82d917da2eec4c42ef862f25e6030cdb 1125 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 117 322 1.1E-71 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CU254_RS07195 82d917da2eec4c42ef862f25e6030cdb 1125 Gene3D G3DSA:3.20.20.70 525 821 1.4E-72 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS07195 82d917da2eec4c42ef862f25e6030cdb 1125 Gene3D G3DSA:3.30.470.20 204 449 1.5E-99 T 28-03-2018 CU254_RS07195 82d917da2eec4c42ef862f25e6030cdb 1125 PIRSF PIRSF001594 1 1125 0.0 T 28-03-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 CU254_RS07195 82d917da2eec4c42ef862f25e6030cdb 1125 SUPERFAMILY SSF52440 1 112 1.73E-40 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CU254_RS07195 82d917da2eec4c42ef862f25e6030cdb 1125 Pfam PF02436 Conserved carboxylase domain 821 1008 9.2E-58 T 28-03-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 CU254_RS07195 82d917da2eec4c42ef862f25e6030cdb 1125 Gene3D G3DSA:3.10.600.10 965 1042 1.9E-24 T 28-03-2018 CU254_RS07195 82d917da2eec4c42ef862f25e6030cdb 1125 Gene3D G3DSA:3.10.600.10 458 524 1.7E-9 T 28-03-2018 CU254_RS07195 82d917da2eec4c42ef862f25e6030cdb 1125 SUPERFAMILY SSF51569 518 829 1.7E-76 T 28-03-2018 CU254_RS07195 82d917da2eec4c42ef862f25e6030cdb 1125 Pfam PF02785 Biotin carboxylase C-terminal domain 339 447 1.8E-33 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CU254_RS07195 82d917da2eec4c42ef862f25e6030cdb 1125 SUPERFAMILY SSF89000 826 991 5.1E-42 T 28-03-2018 CU254_RS07195 82d917da2eec4c42ef862f25e6030cdb 1125 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 7.5E-40 T 28-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CU254_RS07195 82d917da2eec4c42ef862f25e6030cdb 1125 SUPERFAMILY SSF51246 334 451 3.19E-37 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CU254_RS15205 e9bb459aa4ca6b3e9daf38fa7fa73212 183 SUPERFAMILY SSF50475 17 170 2.41E-36 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS15205 e9bb459aa4ca6b3e9daf38fa7fa73212 183 Gene3D G3DSA:2.30.110.10 15 181 8.4E-35 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS15205 e9bb459aa4ca6b3e9daf38fa7fa73212 183 Pfam PF01613 Flavin reductase like domain 27 166 1.3E-28 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CU254_RS15205 e9bb459aa4ca6b3e9daf38fa7fa73212 183 SMART SM00903 27 167 1.7E-38 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CU254_RS39320 70b32faaee64ed8fedbd70a62dd888de 280 Pfam PF00296 Luciferase-like monooxygenase 14 220 6.5E-25 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS39320 70b32faaee64ed8fedbd70a62dd888de 280 Gene3D G3DSA:3.20.20.30 7 280 3.8E-44 T 28-03-2018 CU254_RS39320 70b32faaee64ed8fedbd70a62dd888de 280 SUPERFAMILY SSF51679 2 277 8.54E-42 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS31120 c7935483f2326283af0e52a6638a807b 228 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 144 223 2.5E-24 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CU254_RS31120 c7935483f2326283af0e52a6638a807b 228 PRINTS PR00107 Phosphocarrier protein signature 194 211 3.9E-11 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CU254_RS31120 c7935483f2326283af0e52a6638a807b 228 PRINTS PR00107 Phosphocarrier protein signature 179 194 3.9E-11 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CU254_RS31120 c7935483f2326283af0e52a6638a807b 228 PRINTS PR00107 Phosphocarrier protein signature 154 170 3.9E-11 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CU254_RS31120 c7935483f2326283af0e52a6638a807b 228 TIGRFAM TIGR02364 dha_pts: dihydroxyacetone kinase, phosphotransfer subunit 3 121 3.5E-36 T 28-03-2018 IPR012844 Dihydroxyacetone kinase phosphotransferase subunit, N-terminal domain CU254_RS31120 c7935483f2326283af0e52a6638a807b 228 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 154 161 - T 28-03-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site CU254_RS31120 c7935483f2326283af0e52a6638a807b 228 SUPERFAMILY SSF55594 143 228 2.36E-23 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CU254_RS31120 c7935483f2326283af0e52a6638a807b 228 Gene3D G3DSA:3.30.1340.10 142 228 8.1E-27 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CU254_RS31120 c7935483f2326283af0e52a6638a807b 228 SUPERFAMILY SSF53062 2 122 4.58E-32 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CU254_RS31120 c7935483f2326283af0e52a6638a807b 228 Gene3D G3DSA:3.40.50.510 1 140 1.6E-35 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CU254_RS31120 c7935483f2326283af0e52a6638a807b 228 Pfam PF00381 PTS HPr component phosphorylation site 144 223 3.2E-24 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CU254_RS31120 c7935483f2326283af0e52a6638a807b 228 Pfam PF03610 PTS system fructose IIA component 4 114 2.7E-25 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CU254_RS29125 0f31f1d8b96b2d10acc4dfca84b9f584 439 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 179 194 - T 28-03-2018 IPR019826 Carboxylesterase type B, active site CU254_RS29125 0f31f1d8b96b2d10acc4dfca84b9f584 439 Gene3D G3DSA:3.40.50.1820 2 320 2.3E-82 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS29125 0f31f1d8b96b2d10acc4dfca84b9f584 439 SUPERFAMILY SSF53474 6 437 1.07E-94 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS29125 0f31f1d8b96b2d10acc4dfca84b9f584 439 ProSitePatterns PS01173 Lipolytic enzymes "G-D-X-G" family, putative histidine active site. 108 124 - T 28-03-2018 IPR002168 Lipase, GDXG, putative histidine active site GO:0008152|GO:0016787 Reactome: R-HSA-163560 CU254_RS29125 0f31f1d8b96b2d10acc4dfca84b9f584 439 Gene3D G3DSA:3.40.50.1820 321 439 8.8E-16 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS29125 0f31f1d8b96b2d10acc4dfca84b9f584 439 Pfam PF00135 Carboxylesterase family 6 316 1.7E-73 T 28-03-2018 IPR002018 Carboxylesterase, type B CU254_RS29125 0f31f1d8b96b2d10acc4dfca84b9f584 439 Pfam PF00135 Carboxylesterase family 324 422 9.8E-5 T 28-03-2018 IPR002018 Carboxylesterase, type B CU254_RS16325 67f7826f874cf0e15ac6145749542367 434 PRINTS PR00732 Glycosyl hydrolase family 4 signature 110 130 5.4E-32 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CU254_RS16325 67f7826f874cf0e15ac6145749542367 434 PRINTS PR00732 Glycosyl hydrolase family 4 signature 73 89 5.4E-32 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CU254_RS16325 67f7826f874cf0e15ac6145749542367 434 PRINTS PR00732 Glycosyl hydrolase family 4 signature 94 107 5.4E-32 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CU254_RS16325 67f7826f874cf0e15ac6145749542367 434 PRINTS PR00732 Glycosyl hydrolase family 4 signature 165 176 5.4E-32 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CU254_RS16325 67f7826f874cf0e15ac6145749542367 434 PRINTS PR00732 Glycosyl hydrolase family 4 signature 191 203 5.4E-32 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CU254_RS16325 67f7826f874cf0e15ac6145749542367 434 PRINTS PR00732 Glycosyl hydrolase family 4 signature 139 156 5.4E-32 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CU254_RS16325 67f7826f874cf0e15ac6145749542367 434 PRINTS PR00732 Glycosyl hydrolase family 4 signature 4 19 5.4E-32 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CU254_RS16325 67f7826f874cf0e15ac6145749542367 434 SUPERFAMILY SSF51735 2 166 1.53E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS16325 67f7826f874cf0e15ac6145749542367 434 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 195 400 2.4E-57 T 28-03-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 CU254_RS16325 67f7826f874cf0e15ac6145749542367 434 SUPERFAMILY SSF56327 169 426 7.43E-64 T 28-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CU254_RS16325 67f7826f874cf0e15ac6145749542367 434 Gene3D G3DSA:3.90.1820.10 270 431 3.7E-33 T 28-03-2018 CU254_RS16325 67f7826f874cf0e15ac6145749542367 434 Gene3D G3DSA:3.90.1820.10 1 269 5.4E-72 T 28-03-2018 CU254_RS16325 67f7826f874cf0e15ac6145749542367 434 Pfam PF02056 Family 4 glycosyl hydrolase 4 185 2.4E-55 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CU254_RS12170 b0a0fcf59832f306b6a49dbbfc1d712a 141 SUPERFAMILY SSF54593 1 138 3.95E-24 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS12170 b0a0fcf59832f306b6a49dbbfc1d712a 141 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 115 1.1E-9 T 28-03-2018 CU254_RS12170 b0a0fcf59832f306b6a49dbbfc1d712a 141 Gene3D G3DSA:3.10.180.10 1 141 3.4E-22 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS22840 bfdac048c903f0ffbc8ea65478a470f5 210 SUPERFAMILY SSF48498 90 172 2.67E-16 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS22840 bfdac048c903f0ffbc8ea65478a470f5 210 Pfam PF13305 WHG domain 93 171 6.5E-9 T 28-03-2018 IPR025996 WHG domain CU254_RS22840 bfdac048c903f0ffbc8ea65478a470f5 210 Gene3D G3DSA:1.10.10.60 1 40 6.1E-11 T 28-03-2018 CU254_RS22840 bfdac048c903f0ffbc8ea65478a470f5 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 65 3.9E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS22840 bfdac048c903f0ffbc8ea65478a470f5 210 Gene3D G3DSA:1.10.260.40 41 67 5.9E-10 T 28-03-2018 CU254_RS22840 bfdac048c903f0ffbc8ea65478a470f5 210 SUPERFAMILY SSF46689 10 80 8.98E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS22840 bfdac048c903f0ffbc8ea65478a470f5 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 2.3E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS22840 bfdac048c903f0ffbc8ea65478a470f5 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 2.3E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS22840 bfdac048c903f0ffbc8ea65478a470f5 210 Gene3D G3DSA:1.10.357.10 68 208 6.1E-24 T 28-03-2018 CU254_RS09410 bcbdab56ca4d739bf3a28c88cb58979c 426 Gene3D G3DSA:3.30.559.10 2 178 3.7E-8 T 28-03-2018 CU254_RS09410 bcbdab56ca4d739bf3a28c88cb58979c 426 Pfam PF06974 Protein of unknown function (DUF1298) 277 422 3.3E-21 T 28-03-2018 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CU254_RS09410 bcbdab56ca4d739bf3a28c88cb58979c 426 SUPERFAMILY SSF52777 4 158 1.11E-10 T 28-03-2018 CU254_RS09410 bcbdab56ca4d739bf3a28c88cb58979c 426 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 6 169 7.5E-34 T 28-03-2018 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CU254_RS15845 5f06798d0340408614ceaecf004a234c 457 Pfam PF00294 pfkB family carbohydrate kinase 4 288 2.0E-20 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CU254_RS15845 5f06798d0340408614ceaecf004a234c 457 Pfam PF01467 Cytidylyltransferase-like 328 420 4.8E-16 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CU254_RS15845 5f06798d0340408614ceaecf004a234c 457 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 244 257 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CU254_RS15845 5f06798d0340408614ceaecf004a234c 457 Gene3D G3DSA:3.40.1190.20 1 295 8.4E-37 T 28-03-2018 IPR029056 Ribokinase-like CU254_RS15845 5f06798d0340408614ceaecf004a234c 457 SUPERFAMILY SSF52374 325 451 9.01E-24 T 28-03-2018 CU254_RS15845 5f06798d0340408614ceaecf004a234c 457 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 326 390 1.2E-16 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CU254_RS15845 5f06798d0340408614ceaecf004a234c 457 SUPERFAMILY SSF53613 4 293 2.03E-33 T 28-03-2018 IPR029056 Ribokinase-like CU254_RS15845 5f06798d0340408614ceaecf004a234c 457 Gene3D G3DSA:3.40.50.620 309 457 3.3E-26 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS26395 c5ca1d67b75d9cea006586e76d06399a 139 Pfam PF10722 Putative bacterial sensory transduction regulator 24 134 8.8E-5 T 28-03-2018 IPR019660 Putative sensory transduction regulator YbjN CU254_RS26395 c5ca1d67b75d9cea006586e76d06399a 139 Gene3D G3DSA:3.30.1460.10 11 135 6.9E-10 T 28-03-2018 CU254_RS39195 92784fc5bbb63354439001fece6e21a1 338 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 64 241 8.7E-62 T 28-03-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 CU254_RS39195 92784fc5bbb63354439001fece6e21a1 338 Gene3D G3DSA:1.10.10.730 157 204 1.2E-16 T 28-03-2018 CU254_RS39195 92784fc5bbb63354439001fece6e21a1 338 SUPERFAMILY SSF110849 62 159 4.19E-28 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CU254_RS39195 92784fc5bbb63354439001fece6e21a1 338 Pfam PF02195 ParB-like nuclease domain 67 156 6.2E-24 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CU254_RS39195 92784fc5bbb63354439001fece6e21a1 338 SUPERFAMILY SSF109709 148 257 1.07E-31 T 28-03-2018 CU254_RS39195 92784fc5bbb63354439001fece6e21a1 338 Gene3D G3DSA:3.90.1530.10 54 156 8.5E-37 T 28-03-2018 CU254_RS39195 92784fc5bbb63354439001fece6e21a1 338 SMART SM00470 66 156 3.2E-31 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CU254_RS27190 f8c46fa3791c664234c33ccc0a8c0529 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 58 74 9.0E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS27190 f8c46fa3791c664234c33ccc0a8c0529 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 75 90 9.0E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS27190 f8c46fa3791c664234c33ccc0a8c0529 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 94 110 9.0E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS27190 f8c46fa3791c664234c33ccc0a8c0529 150 SMART SM00347 32 134 2.3E-16 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS27190 f8c46fa3791c664234c33ccc0a8c0529 150 Gene3D G3DSA:1.10.10.10 16 142 1.2E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS27190 f8c46fa3791c664234c33ccc0a8c0529 150 SUPERFAMILY SSF46785 11 138 2.32E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS27190 f8c46fa3791c664234c33ccc0a8c0529 150 Pfam PF01047 MarR family 39 98 3.0E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS36530 dc29f0d86d576019c03b036b241757a1 231 Pfam PF00482 Type II secretion system (T2SS), protein F 94 215 9.5E-17 T 28-03-2018 IPR018076 Type II secretion system F domain CU254_RS12885 bf047189e37c8ac5a4c34c30a8f85c94 287 Gene3D G3DSA:1.10.1040.10 188 287 5.6E-29 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CU254_RS12885 bf047189e37c8ac5a4c34c30a8f85c94 287 SUPERFAMILY SSF48179 189 286 2.98E-29 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CU254_RS12885 bf047189e37c8ac5a4c34c30a8f85c94 287 SUPERFAMILY SSF51735 3 186 9.87E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS12885 bf047189e37c8ac5a4c34c30a8f85c94 287 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 7 186 4.1E-52 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CU254_RS12885 bf047189e37c8ac5a4c34c30a8f85c94 287 PIRSF PIRSF000105 3 287 1.3E-72 T 28-03-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 CU254_RS12885 bf047189e37c8ac5a4c34c30a8f85c94 287 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 189 285 4.1E-27 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CU254_RS12885 bf047189e37c8ac5a4c34c30a8f85c94 287 Gene3D G3DSA:3.40.50.720 2 187 4.9E-45 T 28-03-2018 CU254_RS03945 0350c0fdb0802d9c512d420aec6b56fb 211 Gene3D G3DSA:1.20.1260.10 2 211 3.7E-42 T 28-03-2018 IPR012347 Ferritin-related CU254_RS03945 0350c0fdb0802d9c512d420aec6b56fb 211 Pfam PF13794 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like 3 182 5.3E-82 T 28-03-2018 CU254_RS03945 0350c0fdb0802d9c512d420aec6b56fb 211 SUPERFAMILY SSF47240 6 125 5.09E-7 T 28-03-2018 IPR009078 Ferritin-like superfamily CU254_RS15320 ba89162c9096d7ce85c88c81346e44dd 309 SUPERFAMILY SSF47203 172 293 1.27E-25 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS15320 ba89162c9096d7ce85c88c81346e44dd 309 Gene3D G3DSA:1.10.540.10 1 113 6.6E-15 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS15320 ba89162c9096d7ce85c88c81346e44dd 309 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 80 1.2E-11 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS15320 ba89162c9096d7ce85c88c81346e44dd 309 SUPERFAMILY SSF56645 5 89 1.19E-12 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS15320 ba89162c9096d7ce85c88c81346e44dd 309 Gene3D G3DSA:1.20.140.10 164 290 3.2E-24 T 28-03-2018 CU254_RS15320 ba89162c9096d7ce85c88c81346e44dd 309 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 172 282 3.3E-17 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS05570 c9bb7ff8db2b8818f06903f842f51d51 520 Gene3D G3DSA:2.160.10.10 117 282 0.0014 T 28-03-2018 CU254_RS15860 55e912f65752e128ba2e51f2318c0866 478 SUPERFAMILY SSF52413 308 422 1.22E-32 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CU254_RS15860 55e912f65752e128ba2e51f2318c0866 478 SUPERFAMILY SSF48179 197 293 2.72E-28 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CU254_RS15860 55e912f65752e128ba2e51f2318c0866 478 Gene3D G3DSA:3.40.50.720 1 194 2.7E-48 T 28-03-2018 CU254_RS15860 55e912f65752e128ba2e51f2318c0866 478 PIRSF PIRSF000124 3 428 1.9E-118 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CU254_RS15860 55e912f65752e128ba2e51f2318c0866 478 SUPERFAMILY SSF51735 4 186 4.72E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS15860 55e912f65752e128ba2e51f2318c0866 478 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 317 413 5.6E-28 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CU254_RS15860 55e912f65752e128ba2e51f2318c0866 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 29 2.9E-5 T 28-03-2018 CU254_RS15860 55e912f65752e128ba2e51f2318c0866 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 225 245 2.9E-5 T 28-03-2018 CU254_RS15860 55e912f65752e128ba2e51f2318c0866 478 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 4 409 3.9E-122 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CU254_RS15860 55e912f65752e128ba2e51f2318c0866 478 PIRSF PIRSF500134 3 431 2.6E-135 T 28-03-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 CU254_RS15860 55e912f65752e128ba2e51f2318c0866 478 Gene3D G3DSA:3.40.50.720 220 424 1.1E-65 T 28-03-2018 CU254_RS15860 55e912f65752e128ba2e51f2318c0866 478 Gene3D G3DSA:1.20.5.100 197 219 9.0E-11 T 28-03-2018 CU254_RS15860 55e912f65752e128ba2e51f2318c0866 478 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 4 173 1.5E-48 T 28-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CU254_RS15860 55e912f65752e128ba2e51f2318c0866 478 SMART SM00984 316 413 3.4E-38 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CU254_RS15860 55e912f65752e128ba2e51f2318c0866 478 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 197 288 1.7E-32 T 28-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CU254_RS20620 7c2f9624edd884d1f771ca2f7af49fd3 648 Gene3D G3DSA:3.40.1710.10 47 247 1.0E-25 T 28-03-2018 CU254_RS20620 7c2f9624edd884d1f771ca2f7af49fd3 648 Gene3D G3DSA:1.20.120.570 304 424 8.0E-5 T 28-03-2018 CU254_RS20620 7c2f9624edd884d1f771ca2f7af49fd3 648 Pfam PF12698 ABC-2 family transporter protein 28 154 2.6E-9 T 28-03-2018 CU254_RS20620 7c2f9624edd884d1f771ca2f7af49fd3 648 Pfam PF12698 ABC-2 family transporter protein 357 625 3.0E-12 T 28-03-2018 CU254_RS20620 7c2f9624edd884d1f771ca2f7af49fd3 648 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 10 173 2.2E-53 T 28-03-2018 IPR017500 Phage infection protein, YhgE, N-terminal CU254_RS20620 7c2f9624edd884d1f771ca2f7af49fd3 648 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 430 635 3.0E-59 T 28-03-2018 IPR017501 Phage infection protein, YhgE, C-terminal CU254_RS15375 a8980a438e1f07d4a64e201e0bd1d604 137 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 1 115 2.3E-7 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase CU254_RS15375 a8980a438e1f07d4a64e201e0bd1d604 137 SUPERFAMILY SSF55961 2 134 4.28E-31 T 28-03-2018 CU254_RS15375 a8980a438e1f07d4a64e201e0bd1d604 137 Gene3D G3DSA:3.30.530.20 1 135 2.8E-17 T 28-03-2018 IPR023393 START-like domain CU254_RS38630 e18e1b77eb0c1f5c4ba1e54bbffb9130 219 Gene3D G3DSA:1.10.357.10 76 211 4.6E-20 T 28-03-2018 CU254_RS38630 e18e1b77eb0c1f5c4ba1e54bbffb9130 219 Gene3D G3DSA:1.10.10.60 56 75 1.6E-7 T 28-03-2018 CU254_RS38630 e18e1b77eb0c1f5c4ba1e54bbffb9130 219 Gene3D G3DSA:1.10.10.60 1 55 1.2E-19 T 28-03-2018 CU254_RS38630 e18e1b77eb0c1f5c4ba1e54bbffb9130 219 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 67 2.0E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS38630 e18e1b77eb0c1f5c4ba1e54bbffb9130 219 SUPERFAMILY SSF46689 11 92 3.69E-19 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS38630 e18e1b77eb0c1f5c4ba1e54bbffb9130 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 2.6E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS38630 e18e1b77eb0c1f5c4ba1e54bbffb9130 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 2.6E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS19670 2f41c1474de41b93c3a9c9c828baf6dc 120 SUPERFAMILY SSF54909 3 116 3.75E-22 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS19670 2f41c1474de41b93c3a9c9c828baf6dc 120 Pfam PF03795 YCII-related domain 20 115 2.7E-12 T 28-03-2018 IPR005545 YCII-related CU254_RS19670 2f41c1474de41b93c3a9c9c828baf6dc 120 Gene3D G3DSA:3.30.70.1060 1 120 4.4E-32 T 28-03-2018 CU254_RS36220 e39f54e9e89879e3c4f92e15b208614f 849 Pfam PF07724 AAA domain (Cdc48 subfamily) 542 715 4.7E-50 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CU254_RS36220 e39f54e9e89879e3c4f92e15b208614f 849 Gene3D G3DSA:1.10.1780.10 79 199 2.9E-28 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CU254_RS36220 e39f54e9e89879e3c4f92e15b208614f 849 Pfam PF02151 UvrB/uvrC motif 423 455 5.6E-8 T 28-03-2018 IPR001943 UVR domain GO:0005515 CU254_RS36220 e39f54e9e89879e3c4f92e15b208614f 849 Gene3D G3DSA:1.10.1780.10 1 78 3.0E-28 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CU254_RS36220 e39f54e9e89879e3c4f92e15b208614f 849 Gene3D G3DSA:3.40.50.300 200 348 1.6E-17 T 28-03-2018 CU254_RS36220 e39f54e9e89879e3c4f92e15b208614f 849 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 93 142 3.9E-17 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CU254_RS36220 e39f54e9e89879e3c4f92e15b208614f 849 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 16 68 6.4E-18 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CU254_RS36220 e39f54e9e89879e3c4f92e15b208614f 849 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 211 323 7.7E-13 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CU254_RS36220 e39f54e9e89879e3c4f92e15b208614f 849 SUPERFAMILY SSF52540 492 806 1.16E-76 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS36220 e39f54e9e89879e3c4f92e15b208614f 849 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 721 801 6.9E-26 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CU254_RS36220 e39f54e9e89879e3c4f92e15b208614f 849 SMART SM01086 721 812 1.3E-35 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CU254_RS36220 e39f54e9e89879e3c4f92e15b208614f 849 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 547 565 1.3E-38 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CU254_RS36220 e39f54e9e89879e3c4f92e15b208614f 849 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 621 639 1.3E-38 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CU254_RS36220 e39f54e9e89879e3c4f92e15b208614f 849 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 654 668 1.3E-38 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CU254_RS36220 e39f54e9e89879e3c4f92e15b208614f 849 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 592 610 1.3E-38 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CU254_RS36220 e39f54e9e89879e3c4f92e15b208614f 849 SUPERFAMILY SSF52540 169 468 4.61E-74 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS36220 e39f54e9e89879e3c4f92e15b208614f 849 Gene3D G3DSA:1.10.8.60 721 827 1.2E-23 T 28-03-2018 CU254_RS36220 e39f54e9e89879e3c4f92e15b208614f 849 SUPERFAMILY SSF81923 3 153 5.69E-33 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CU254_RS36220 e39f54e9e89879e3c4f92e15b208614f 849 SMART SM00382 543 722 1.8E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS36220 e39f54e9e89879e3c4f92e15b208614f 849 SMART SM00382 206 350 5.7E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS36220 e39f54e9e89879e3c4f92e15b208614f 849 Gene3D G3DSA:3.40.50.300 498 720 1.9E-53 T 28-03-2018 CU254_RS36220 e39f54e9e89879e3c4f92e15b208614f 849 Gene3D G3DSA:1.10.8.60 350 493 8.2E-43 T 28-03-2018 CU254_RS36220 e39f54e9e89879e3c4f92e15b208614f 849 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 301 313 - T 28-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 CU254_RS40860 c52722bbef488c2f464f13c697b83577 210 Gene3D G3DSA:3.40.50.720 1 209 1.5E-25 T 28-03-2018 CU254_RS40860 c52722bbef488c2f464f13c697b83577 210 SUPERFAMILY SSF51735 1 208 3.01E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS40860 c52722bbef488c2f464f13c697b83577 210 Pfam PF13460 NAD(P)H-binding 7 197 2.1E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS26380 ccbb18adeacb78b948e7e59a0ad95984 137 Pfam PF01475 Ferric uptake regulator family 12 128 1.0E-34 T 28-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CU254_RS26380 ccbb18adeacb78b948e7e59a0ad95984 137 SUPERFAMILY SSF46785 12 133 8.45E-37 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS26380 ccbb18adeacb78b948e7e59a0ad95984 137 Gene3D G3DSA:1.10.10.10 10 89 1.2E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS06960 48bacc4cab9275366fee7f8a35fad63f 412 Pfam PF01494 FAD binding domain 7 333 4.3E-57 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CU254_RS06960 48bacc4cab9275366fee7f8a35fad63f 412 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 157 172 9.4E-20 T 28-03-2018 CU254_RS06960 48bacc4cab9275366fee7f8a35fad63f 412 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 297 313 9.4E-20 T 28-03-2018 CU254_RS06960 48bacc4cab9275366fee7f8a35fad63f 412 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 9.4E-20 T 28-03-2018 CU254_RS06960 48bacc4cab9275366fee7f8a35fad63f 412 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 282 297 9.4E-20 T 28-03-2018 CU254_RS06960 48bacc4cab9275366fee7f8a35fad63f 412 Gene3D G3DSA:3.50.50.60 2 386 2.4E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS06960 48bacc4cab9275366fee7f8a35fad63f 412 SUPERFAMILY SSF51905 269 359 6.48E-58 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS06960 48bacc4cab9275366fee7f8a35fad63f 412 SUPERFAMILY SSF51905 5 178 6.48E-58 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS01145 c703efd66017d44421a98c5e7cbb86cc 437 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 415 25.412 T 28-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CU254_RS01145 c703efd66017d44421a98c5e7cbb86cc 437 Gene3D G3DSA:3.40.50.720 159 315 3.8E-22 T 28-03-2018 CU254_RS01145 c703efd66017d44421a98c5e7cbb86cc 437 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 6 156 1.5E-43 T 28-03-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CU254_RS01145 c703efd66017d44421a98c5e7cbb86cc 437 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 99 122 - T 28-03-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CU254_RS01145 c703efd66017d44421a98c5e7cbb86cc 437 SUPERFAMILY SSF69742 1 158 1.31E-42 T 28-03-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CU254_RS01145 c703efd66017d44421a98c5e7cbb86cc 437 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 3 416 1.4E-116 T 28-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CU254_RS01145 c703efd66017d44421a98c5e7cbb86cc 437 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 169 301 2.4E-26 T 28-03-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase CU254_RS01145 c703efd66017d44421a98c5e7cbb86cc 437 PIRSF PIRSF000445 1 430 5.4E-127 T 28-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CU254_RS01145 c703efd66017d44421a98c5e7cbb86cc 437 Gene3D G3DSA:1.10.1200.70 330 418 1.3E-21 T 28-03-2018 CU254_RS01145 c703efd66017d44421a98c5e7cbb86cc 437 SUPERFAMILY SSF51735 165 300 1.16E-23 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS01145 c703efd66017d44421a98c5e7cbb86cc 437 SUPERFAMILY SSF69075 317 418 1.83E-16 T 28-03-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CU254_RS01145 c703efd66017d44421a98c5e7cbb86cc 437 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 318 416 9.8E-21 T 28-03-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CU254_RS12140 915b1ec65b7b60849533040ba91ec6db 198 Gene3D G3DSA:2.60.40.1220 39 135 6.8E-26 T 28-03-2018 CU254_RS12140 915b1ec65b7b60849533040ba91ec6db 198 Pfam PF04234 CopC domain 40 133 2.8E-25 T 28-03-2018 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 CU254_RS12140 915b1ec65b7b60849533040ba91ec6db 198 SUPERFAMILY SSF81296 39 134 8.4E-24 T 28-03-2018 IPR014756 Immunoglobulin E-set CU254_RS22025 bffe7a0f8edb6c0454bbb65a9a1c5ba0 160 SUPERFAMILY SSF54909 67 152 2.15E-17 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS22025 bffe7a0f8edb6c0454bbb65a9a1c5ba0 160 Pfam PF01037 Lrp/AsnC ligand binding domain 74 143 2.8E-14 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CU254_RS22025 bffe7a0f8edb6c0454bbb65a9a1c5ba0 160 Gene3D G3DSA:1.10.10.10 1 55 4.5E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS22025 bffe7a0f8edb6c0454bbb65a9a1c5ba0 160 SUPERFAMILY SSF46785 7 92 6.23E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS22025 bffe7a0f8edb6c0454bbb65a9a1c5ba0 160 Pfam PF13404 AsnC-type helix-turn-helix domain 7 48 7.6E-12 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS22025 bffe7a0f8edb6c0454bbb65a9a1c5ba0 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 23 34 9.8E-7 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS22025 bffe7a0f8edb6c0454bbb65a9a1c5ba0 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 7 23 9.8E-7 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS22025 bffe7a0f8edb6c0454bbb65a9a1c5ba0 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 34 53 9.8E-7 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS22025 bffe7a0f8edb6c0454bbb65a9a1c5ba0 160 SMART SM00344 7 113 7.0E-17 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CU254_RS22025 bffe7a0f8edb6c0454bbb65a9a1c5ba0 160 Gene3D G3DSA:3.30.70.920 60 153 1.5E-20 T 28-03-2018 CU254_RS28945 86d1105f2ea5159c2ca26d6948a16139 162 Gene3D G3DSA:2.30.22.10 103 160 1.6E-18 T 28-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 CU254_RS28945 86d1105f2ea5159c2ca26d6948a16139 162 SUPERFAMILY SSF51064 108 160 1.57E-13 T 28-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 CU254_RS28945 86d1105f2ea5159c2ca26d6948a16139 162 ProSitePatterns PS01071 grpE protein signature. 115 158 - T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CU254_RS28945 86d1105f2ea5159c2ca26d6948a16139 162 Gene3D G3DSA:3.90.20.20 2 101 1.1E-14 T 28-03-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 CU254_RS28945 86d1105f2ea5159c2ca26d6948a16139 162 Pfam PF01025 GrpE 3 160 1.3E-32 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CU254_RS28945 86d1105f2ea5159c2ca26d6948a16139 162 Hamap MF_01151 Protein GrpE [grpE]. 2 160 14.991 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CU254_RS28945 86d1105f2ea5159c2ca26d6948a16139 162 SUPERFAMILY SSF58014 15 99 1.28E-14 T 28-03-2018 CU254_RS28945 86d1105f2ea5159c2ca26d6948a16139 162 PRINTS PR00773 GrpE protein signature 59 74 3.1E-18 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CU254_RS28945 86d1105f2ea5159c2ca26d6948a16139 162 PRINTS PR00773 GrpE protein signature 139 158 3.1E-18 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CU254_RS28945 86d1105f2ea5159c2ca26d6948a16139 162 PRINTS PR00773 GrpE protein signature 112 127 3.1E-18 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CU254_RS28945 86d1105f2ea5159c2ca26d6948a16139 162 PRINTS PR00773 GrpE protein signature 31 47 3.1E-18 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CU254_RS07465 b7375e1daac14817f322197b51bd563d 433 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 34 132 3.4E-9 T 28-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CU254_RS07465 b7375e1daac14817f322197b51bd563d 433 SUPERFAMILY SSF51604 182 426 5.63E-66 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CU254_RS07465 b7375e1daac14817f322197b51bd563d 433 Pfam PF13378 Enolase C-terminal domain-like 200 414 1.3E-60 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CU254_RS07465 b7375e1daac14817f322197b51bd563d 433 SMART SM00922 197 293 5.4E-25 T 28-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CU254_RS07465 b7375e1daac14817f322197b51bd563d 433 SUPERFAMILY SSF54826 3 135 7.41E-36 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CU254_RS07465 b7375e1daac14817f322197b51bd563d 433 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 243 274 - T 28-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 CU254_RS07465 b7375e1daac14817f322197b51bd563d 433 Gene3D G3DSA:3.20.20.120 178 433 3.6E-64 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CU254_RS07465 b7375e1daac14817f322197b51bd563d 433 Gene3D G3DSA:3.30.390.10 1 177 3.7E-42 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CU254_RS04435 64904877aa9416fbfbebc91c674ff276 193 Pfam PF04978 Protein of unknown function (DUF664) 15 167 9.7E-46 T 28-03-2018 IPR007061 Protein of unknown function DUF664 CU254_RS04435 64904877aa9416fbfbebc91c674ff276 193 SUPERFAMILY SSF109854 4 166 1.28E-37 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CU254_RS04435 64904877aa9416fbfbebc91c674ff276 193 Gene3D G3DSA:1.20.120.450 4 171 8.9E-34 T 28-03-2018 CU254_RS25120 1e5e04ca91e70a7b6d0fc3da0899dcc7 328 Gene3D G3DSA:1.10.1740.10 2 79 5.6E-22 T 28-03-2018 CU254_RS25120 1e5e04ca91e70a7b6d0fc3da0899dcc7 328 SUPERFAMILY SSF88659 124 186 1.16E-11 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS25120 1e5e04ca91e70a7b6d0fc3da0899dcc7 328 Gene3D G3DSA:1.10.10.10 110 180 3.6E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS25120 1e5e04ca91e70a7b6d0fc3da0899dcc7 328 Pfam PF12680 SnoaL-like domain 208 308 3.6E-6 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CU254_RS25120 1e5e04ca91e70a7b6d0fc3da0899dcc7 328 TIGRFAM TIGR02960 SigX5: RNA polymerase sigma-70 factor, TIGR02960 family 4 320 2.4E-110 T 28-03-2018 IPR014305 RNA polymerase sigma-G type, actinobacteria CU254_RS25120 1e5e04ca91e70a7b6d0fc3da0899dcc7 328 Gene3D G3DSA:3.10.450.50 181 318 9.0E-16 T 28-03-2018 CU254_RS25120 1e5e04ca91e70a7b6d0fc3da0899dcc7 328 SUPERFAMILY SSF54427 199 311 2.57E-13 T 28-03-2018 IPR032710 NTF2-like domain CU254_RS25120 1e5e04ca91e70a7b6d0fc3da0899dcc7 328 SUPERFAMILY SSF88946 5 81 5.69E-23 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS25120 1e5e04ca91e70a7b6d0fc3da0899dcc7 328 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 8 186 2.1E-22 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS25120 1e5e04ca91e70a7b6d0fc3da0899dcc7 328 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 32 63 - T 28-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS25120 1e5e04ca91e70a7b6d0fc3da0899dcc7 328 Pfam PF08281 Sigma-70, region 4 131 182 9.3E-15 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS25120 1e5e04ca91e70a7b6d0fc3da0899dcc7 328 Pfam PF04542 Sigma-70 region 2 12 77 1.5E-18 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS28775 a697a9ac53d9e30a01c29f197f1df509 381 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 29 362 6.3E-101 T 28-03-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001 CU254_RS28775 a697a9ac53d9e30a01c29f197f1df509 381 SUPERFAMILY SSF53756 3 365 9.74E-105 T 28-03-2018 CU254_RS28775 a697a9ac53d9e30a01c29f197f1df509 381 Gene3D G3DSA:3.40.50.2000 205 342 2.1E-37 T 28-03-2018 CU254_RS28775 a697a9ac53d9e30a01c29f197f1df509 381 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 7 362 1.1E-111 T 28-03-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 CU254_RS28775 a697a9ac53d9e30a01c29f197f1df509 381 Gene3D G3DSA:3.40.50.2000 1 204 4.8E-60 T 28-03-2018 CU254_RS22440 3f92cb1c7ab390b987c28e23431e815a 308 Gene3D G3DSA:3.40.50.1370 140 303 4.4E-55 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CU254_RS22440 3f92cb1c7ab390b987c28e23431e815a 308 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 45 52 - T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CU254_RS22440 3f92cb1c7ab390b987c28e23431e815a 308 PRINTS PR00102 Ornithine carbamoyltransferase signature 282 293 4.1E-29 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CU254_RS22440 3f92cb1c7ab390b987c28e23431e815a 308 PRINTS PR00102 Ornithine carbamoyltransferase signature 116 130 4.1E-29 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CU254_RS22440 3f92cb1c7ab390b987c28e23431e815a 308 PRINTS PR00102 Ornithine carbamoyltransferase signature 76 89 4.1E-29 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CU254_RS22440 3f92cb1c7ab390b987c28e23431e815a 308 PRINTS PR00102 Ornithine carbamoyltransferase signature 43 57 4.1E-29 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CU254_RS22440 3f92cb1c7ab390b987c28e23431e815a 308 PRINTS PR00102 Ornithine carbamoyltransferase signature 220 230 4.1E-29 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CU254_RS22440 3f92cb1c7ab390b987c28e23431e815a 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 268 291 3.1E-26 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CU254_RS22440 3f92cb1c7ab390b987c28e23431e815a 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 127 138 3.1E-26 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CU254_RS22440 3f92cb1c7ab390b987c28e23431e815a 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 45 64 3.1E-26 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CU254_RS22440 3f92cb1c7ab390b987c28e23431e815a 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 256 265 3.1E-26 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CU254_RS22440 3f92cb1c7ab390b987c28e23431e815a 308 Gene3D G3DSA:3.40.50.1370 1 139 3.7E-52 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CU254_RS22440 3f92cb1c7ab390b987c28e23431e815a 308 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 2 304 75.803 T 28-03-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 CU254_RS22440 3f92cb1c7ab390b987c28e23431e815a 308 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 3 303 1.2E-115 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CU254_RS22440 3f92cb1c7ab390b987c28e23431e815a 308 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 3 140 2.2E-47 T 28-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 CU254_RS22440 3f92cb1c7ab390b987c28e23431e815a 308 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 147 301 2.3E-51 T 28-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 CU254_RS22440 3f92cb1c7ab390b987c28e23431e815a 308 SUPERFAMILY SSF53671 2 305 6.94E-101 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CU254_RS36420 0306e6664b238bf7a95dd6c9f63eb16a 111 Gene3D G3DSA:1.10.10.10 1 111 1.4E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS36420 0306e6664b238bf7a95dd6c9f63eb16a 111 SMART SM00418 11 90 4.1E-18 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS36420 0306e6664b238bf7a95dd6c9f63eb16a 111 Pfam PF12840 Helix-turn-helix domain 11 67 1.6E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS36420 0306e6664b238bf7a95dd6c9f63eb16a 111 SUPERFAMILY SSF46785 11 103 1.27E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS36420 0306e6664b238bf7a95dd6c9f63eb16a 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 13 28 2.7E-5 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS36420 0306e6664b238bf7a95dd6c9f63eb16a 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 46 61 2.7E-5 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS08655 69ec31d3fa1e74f06e234ff166d34356 225 Pfam PF07729 FCD domain 81 201 8.7E-29 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS08655 69ec31d3fa1e74f06e234ff166d34356 225 SUPERFAMILY SSF48008 79 209 2.88E-30 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS08655 69ec31d3fa1e74f06e234ff166d34356 225 Gene3D G3DSA:1.10.10.10 1 65 2.2E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS08655 69ec31d3fa1e74f06e234ff166d34356 225 Gene3D G3DSA:1.20.120.530 76 218 1.1E-32 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS08655 69ec31d3fa1e74f06e234ff166d34356 225 SMART SM00895 81 202 2.6E-25 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS08655 69ec31d3fa1e74f06e234ff166d34356 225 SMART SM00345 4 63 4.6E-20 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS08655 69ec31d3fa1e74f06e234ff166d34356 225 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 53 2.3E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS08655 69ec31d3fa1e74f06e234ff166d34356 225 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 23 37 2.3E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS08655 69ec31d3fa1e74f06e234ff166d34356 225 SUPERFAMILY SSF46785 2 67 1.86E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS08655 69ec31d3fa1e74f06e234ff166d34356 225 Pfam PF00392 Bacterial regulatory proteins, gntR family 2 63 3.7E-19 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS05470 7a51d21983ce1e5923aeed40cc3f898d 747 Gene3D G3DSA:1.10.520.10 449 610 1.6E-42 T 28-03-2018 CU254_RS05470 7a51d21983ce1e5923aeed40cc3f898d 747 TIGRFAM TIGR00198 cat_per_HPI: catalase/peroxidase HPI 32 747 0.0 T 28-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 CU254_RS05470 7a51d21983ce1e5923aeed40cc3f898d 747 ProSitePatterns PS00436 Peroxidases active site signature. 100 111 - T 28-03-2018 IPR019794 Peroxidase, active site GO:0004601|GO:0055114 CU254_RS05470 7a51d21983ce1e5923aeed40cc3f898d 747 PRINTS PR00458 Haem peroxidase superfamily signature 178 190 1.9E-18 T 28-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 CU254_RS05470 7a51d21983ce1e5923aeed40cc3f898d 747 PRINTS PR00458 Haem peroxidase superfamily signature 160 177 1.9E-18 T 28-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 CU254_RS05470 7a51d21983ce1e5923aeed40cc3f898d 747 PRINTS PR00458 Haem peroxidase superfamily signature 324 339 1.9E-18 T 28-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 CU254_RS05470 7a51d21983ce1e5923aeed40cc3f898d 747 PRINTS PR00458 Haem peroxidase superfamily signature 264 279 1.9E-18 T 28-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 CU254_RS05470 7a51d21983ce1e5923aeed40cc3f898d 747 PRINTS PR00458 Haem peroxidase superfamily signature 100 114 1.9E-18 T 28-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 CU254_RS05470 7a51d21983ce1e5923aeed40cc3f898d 747 Gene3D G3DSA:1.10.420.10 611 722 1.7E-35 T 28-03-2018 CU254_RS05470 7a51d21983ce1e5923aeed40cc3f898d 747 Gene3D G3DSA:1.10.420.10 238 405 3.2E-40 T 28-03-2018 CU254_RS05470 7a51d21983ce1e5923aeed40cc3f898d 747 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 272 295 4.5E-44 T 28-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 CU254_RS05470 7a51d21983ce1e5923aeed40cc3f898d 747 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 488 514 4.5E-44 T 28-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 CU254_RS05470 7a51d21983ce1e5923aeed40cc3f898d 747 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 36 58 4.5E-44 T 28-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 CU254_RS05470 7a51d21983ce1e5923aeed40cc3f898d 747 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 62 75 4.5E-44 T 28-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 CU254_RS05470 7a51d21983ce1e5923aeed40cc3f898d 747 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 77 102 4.5E-44 T 28-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 CU254_RS05470 7a51d21983ce1e5923aeed40cc3f898d 747 SUPERFAMILY SSF48113 438 746 1.92E-115 T 28-03-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 CU254_RS05470 7a51d21983ce1e5923aeed40cc3f898d 747 Hamap MF_01961 Catalase-peroxidase [katG]. 15 747 42.608 T 28-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 CU254_RS05470 7a51d21983ce1e5923aeed40cc3f898d 747 Pfam PF00141 Peroxidase 410 720 1.1E-39 T 28-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 CU254_RS05470 7a51d21983ce1e5923aeed40cc3f898d 747 Pfam PF00141 Peroxidase 91 403 8.2E-49 T 28-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 CU254_RS05470 7a51d21983ce1e5923aeed40cc3f898d 747 ProSitePatterns PS00435 Peroxidases proximal heme-ligand signature. 264 274 - T 28-03-2018 IPR019793 Peroxidases heam-ligand binding site Reactome: R-HSA-2408557 CU254_RS05470 7a51d21983ce1e5923aeed40cc3f898d 747 Gene3D G3DSA:1.10.520.10 66 225 1.1E-37 T 28-03-2018 CU254_RS05470 7a51d21983ce1e5923aeed40cc3f898d 747 SUPERFAMILY SSF48113 28 437 4.72E-155 T 28-03-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 CU254_RS27540 e5fce3887ae06babfa4126e9618703cc 529 Gene3D G3DSA:3.20.20.470 186 348 1.4E-36 T 28-03-2018 CU254_RS27540 e5fce3887ae06babfa4126e9618703cc 529 Pfam PF11941 Domain of unknown function (DUF3459) 451 528 1.5E-7 T 28-03-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) CU254_RS27540 e5fce3887ae06babfa4126e9618703cc 529 Pfam PF00128 Alpha amylase, catalytic domain 41 381 3.0E-82 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CU254_RS27540 e5fce3887ae06babfa4126e9618703cc 529 Gene3D G3DSA:3.90.400.10 118 185 1.0E-30 T 28-03-2018 CU254_RS27540 e5fce3887ae06babfa4126e9618703cc 529 Gene3D G3DSA:3.20.20.80 349 468 1.2E-23 T 28-03-2018 CU254_RS27540 e5fce3887ae06babfa4126e9618703cc 529 SUPERFAMILY SSF51445 15 465 2.18E-125 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS27540 e5fce3887ae06babfa4126e9618703cc 529 Gene3D G3DSA:3.20.20.470 4 108 3.0E-34 T 28-03-2018 CU254_RS27540 e5fce3887ae06babfa4126e9618703cc 529 SMART SM00642 26 405 8.4E-117 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CU254_RS40540 6602b3df0e8d80129e59eb5966509e2d 237 SUPERFAMILY SSF49899 46 209 1.11E-27 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CU254_RS40540 6602b3df0e8d80129e59eb5966509e2d 237 Pfam PF01828 Peptidase A4 family 47 206 1.2E-25 T 28-03-2018 IPR000250 Peptidase G1 GO:0004190|GO:0006508 CU254_RS15055 346253b7be505fb383623757993c0381 298 Gene3D G3DSA:3.10.450.50 165 290 1.5E-21 T 28-03-2018 CU254_RS15055 346253b7be505fb383623757993c0381 298 Gene3D G3DSA:1.10.1740.10 6 83 2.8E-13 T 28-03-2018 CU254_RS15055 346253b7be505fb383623757993c0381 298 SUPERFAMILY SSF88946 12 95 1.02E-12 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS15055 346253b7be505fb383623757993c0381 298 Gene3D G3DSA:1.10.10.10 90 164 3.3E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS15055 346253b7be505fb383623757993c0381 298 Pfam PF04542 Sigma-70 region 2 17 80 6.0E-13 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS15055 346253b7be505fb383623757993c0381 298 SUPERFAMILY SSF88659 82 166 5.05E-12 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS15055 346253b7be505fb383623757993c0381 298 Pfam PF08281 Sigma-70, region 4 112 163 3.9E-12 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS15055 346253b7be505fb383623757993c0381 298 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 14 164 3.3E-20 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS15055 346253b7be505fb383623757993c0381 298 SUPERFAMILY SSF54427 177 289 2.25E-16 T 28-03-2018 IPR032710 NTF2-like domain CU254_RS15055 346253b7be505fb383623757993c0381 298 TIGRFAM TIGR02957 SigX4: RNA polymerase sigma-70 factor, TIGR02957 family 14 290 5.1E-110 T 28-03-2018 IPR014303 RNA polymerase sigma-70, ECF type CU254_RS00550 341913f4d57c939edc938651ce333013 547 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 171 4.5E-37 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CU254_RS00550 341913f4d57c939edc938651ce333013 547 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 413 432 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CU254_RS00550 341913f4d57c939edc938651ce333013 547 SUPERFAMILY SSF52518 3 178 4.84E-39 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS00550 341913f4d57c939edc938651ce333013 547 SUPERFAMILY SSF52518 355 531 1.03E-51 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS00550 341913f4d57c939edc938651ce333013 547 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 377 522 1.0E-32 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CU254_RS00550 341913f4d57c939edc938651ce333013 547 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 191 293 2.2E-20 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CU254_RS00550 341913f4d57c939edc938651ce333013 547 Gene3D G3DSA:3.40.50.970 341 531 1.1E-36 T 28-03-2018 CU254_RS00550 341913f4d57c939edc938651ce333013 547 Gene3D G3DSA:3.40.50.1220 191 340 1.7E-25 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CU254_RS00550 341913f4d57c939edc938651ce333013 547 SUPERFAMILY SSF52467 155 333 2.14E-26 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CU254_RS00550 341913f4d57c939edc938651ce333013 547 Gene3D G3DSA:3.40.50.970 1 190 1.4E-37 T 28-03-2018 CU254_RS19010 4cc8e44987ea0dc8ee0e35f25be4a43a 261 Gene3D G3DSA:3.20.20.190 12 261 1.3E-59 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CU254_RS19010 4cc8e44987ea0dc8ee0e35f25be4a43a 261 SUPERFAMILY SSF51695 13 251 4.36E-59 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CU254_RS19010 4cc8e44987ea0dc8ee0e35f25be4a43a 261 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 25 245 2.7E-35 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CU254_RS11425 ff72ba5ad5622583200facb4635eb2de 371 Gene3D G3DSA:1.20.1090.10 174 362 4.1E-59 T 28-03-2018 CU254_RS11425 ff72ba5ad5622583200facb4635eb2de 371 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 7 357 37.493 T 28-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CU254_RS11425 ff72ba5ad5622583200facb4635eb2de 371 PIRSF PIRSF001455 7 353 4.1E-98 T 28-03-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CU254_RS11425 ff72ba5ad5622583200facb4635eb2de 371 SUPERFAMILY SSF56796 13 355 5.23E-100 T 28-03-2018 CU254_RS11425 ff72ba5ad5622583200facb4635eb2de 371 Pfam PF01761 3-dehydroquinate synthase 68 324 9.4E-94 T 28-03-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CU254_RS11425 ff72ba5ad5622583200facb4635eb2de 371 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 17 341 3.6E-106 T 28-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CU254_RS11425 ff72ba5ad5622583200facb4635eb2de 371 Gene3D G3DSA:3.40.50.1970 7 173 1.5E-40 T 28-03-2018 CU254_RS11645 1d728c2ef00f388670fe8c69b38ced63 691 Pfam PF00041 Fibronectin type III domain 264 334 1.2E-11 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CU254_RS11645 1d728c2ef00f388670fe8c69b38ced63 691 Pfam PF00041 Fibronectin type III domain 169 243 1.0E-9 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CU254_RS11645 1d728c2ef00f388670fe8c69b38ced63 691 Pfam PF07995 Glucose / Sorbosone dehydrogenase 370 666 4.4E-72 T 28-03-2018 IPR012938 Glucose/Sorbosone dehydrogenase CU254_RS11645 1d728c2ef00f388670fe8c69b38ced63 691 Gene3D G3DSA:2.60.120.260 31 155 3.8E-32 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS11645 1d728c2ef00f388670fe8c69b38ced63 691 SUPERFAMILY SSF49785 33 153 3.4E-24 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS11645 1d728c2ef00f388670fe8c69b38ced63 691 SMART SM00060 167 242 1.2E-10 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CU254_RS11645 1d728c2ef00f388670fe8c69b38ced63 691 SMART SM00060 262 336 1.1E-12 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CU254_RS11645 1d728c2ef00f388670fe8c69b38ced63 691 Gene3D G3DSA:2.60.40.10 160 258 5.3E-19 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS11645 1d728c2ef00f388670fe8c69b38ced63 691 SUPERFAMILY SSF50952 370 668 7.72E-36 T 28-03-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 CU254_RS11645 1d728c2ef00f388670fe8c69b38ced63 691 PRINTS PR00014 Fibronectin type III repeat signature 276 285 2.6E-5 T 28-03-2018 CU254_RS11645 1d728c2ef00f388670fe8c69b38ced63 691 PRINTS PR00014 Fibronectin type III repeat signature 289 299 2.6E-5 T 28-03-2018 CU254_RS11645 1d728c2ef00f388670fe8c69b38ced63 691 PRINTS PR00014 Fibronectin type III repeat signature 305 323 2.6E-5 T 28-03-2018 CU254_RS11645 1d728c2ef00f388670fe8c69b38ced63 691 PRINTS PR00014 Fibronectin type III repeat signature 323 337 2.6E-5 T 28-03-2018 CU254_RS11645 1d728c2ef00f388670fe8c69b38ced63 691 SUPERFAMILY SSF49265 165 348 3.63E-32 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CU254_RS11645 1d728c2ef00f388670fe8c69b38ced63 691 Gene3D G3DSA:2.60.40.10 259 355 1.7E-20 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS11645 1d728c2ef00f388670fe8c69b38ced63 691 Gene3D G3DSA:2.120.10.30 596 681 1.1E-4 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CU254_RS11645 1d728c2ef00f388670fe8c69b38ced63 691 Gene3D G3DSA:2.120.10.30 360 595 4.0E-55 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CU254_RS11645 1d728c2ef00f388670fe8c69b38ced63 691 Pfam PF03422 Carbohydrate binding module (family 6) 68 144 1.7E-11 T 28-03-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 CU254_RS02285 8fb5d3fb472b5a9743569bacda8ef032 469 Pfam PF07690 Major Facilitator Superfamily 295 442 1.4E-9 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS02285 8fb5d3fb472b5a9743569bacda8ef032 469 Pfam PF00083 Sugar (and other) transporter 29 230 4.1E-30 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CU254_RS02285 8fb5d3fb472b5a9743569bacda8ef032 469 ProSitePatterns PS00217 Sugar transport proteins signature 2. 135 160 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CU254_RS02285 8fb5d3fb472b5a9743569bacda8ef032 469 Gene3D G3DSA:1.20.1250.20 234 466 5.3E-24 T 28-03-2018 CU254_RS02285 8fb5d3fb472b5a9743569bacda8ef032 469 Gene3D G3DSA:1.20.1250.20 21 233 7.0E-26 T 28-03-2018 CU254_RS02285 8fb5d3fb472b5a9743569bacda8ef032 469 SUPERFAMILY SSF103473 23 448 9.55E-65 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS02285 8fb5d3fb472b5a9743569bacda8ef032 469 ProSitePatterns PS00216 Sugar transport proteins signature 1. 318 335 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CU254_RS35090 8ea429ac21f3412745122c9fe8980ea4 143 SUPERFAMILY SSF46785 5 138 1.08E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS35090 8ea429ac21f3412745122c9fe8980ea4 143 Gene3D G3DSA:1.10.10.10 20 108 5.3E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS35090 8ea429ac21f3412745122c9fe8980ea4 143 Pfam PF01047 MarR family 35 91 7.6E-17 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS35090 8ea429ac21f3412745122c9fe8980ea4 143 Gene3D G3DSA:1.10.287.100 109 141 4.0E-9 T 28-03-2018 CU254_RS35090 8ea429ac21f3412745122c9fe8980ea4 143 ProSitePatterns PS01117 MarR-type HTH domain signature. 66 100 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CU254_RS35090 8ea429ac21f3412745122c9fe8980ea4 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 103 8.0E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS35090 8ea429ac21f3412745122c9fe8980ea4 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 68 83 8.0E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS35090 8ea429ac21f3412745122c9fe8980ea4 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 117 137 8.0E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS35090 8ea429ac21f3412745122c9fe8980ea4 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 51 67 8.0E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS35090 8ea429ac21f3412745122c9fe8980ea4 143 SMART SM00347 27 127 4.6E-24 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS09830 e74a31c5167abacf67be4a62480b6c38 143 Gene3D G3DSA:3.10.580.10 1 141 4.0E-28 T 28-03-2018 CU254_RS09830 e74a31c5167abacf67be4a62480b6c38 143 SMART SM00116 79 126 4.1E-8 T 28-03-2018 IPR000644 CBS domain CU254_RS09830 e74a31c5167abacf67be4a62480b6c38 143 SMART SM00116 13 61 4.7E-7 T 28-03-2018 IPR000644 CBS domain CU254_RS09830 e74a31c5167abacf67be4a62480b6c38 143 Pfam PF00571 CBS domain 72 124 1.5E-9 T 28-03-2018 IPR000644 CBS domain CU254_RS09830 e74a31c5167abacf67be4a62480b6c38 143 Pfam PF00571 CBS domain 14 61 1.5E-9 T 28-03-2018 IPR000644 CBS domain CU254_RS09830 e74a31c5167abacf67be4a62480b6c38 143 SUPERFAMILY SSF54631 1 140 1.39E-31 T 28-03-2018 CU254_RS33665 f71ad9f06e680e58e5361eefae129b5a 335 Gene3D G3DSA:1.10.4030.10 28 206 7.8E-4 T 28-03-2018 CU254_RS33665 f71ad9f06e680e58e5361eefae129b5a 335 SUPERFAMILY SSF109998 32 150 4.71E-5 T 28-03-2018 IPR027304 Trigger factor/SurA domain CU254_RS02015 7c2a9e36908dd1d90af9fed30a7a9063 61 Pfam PF00253 Ribosomal protein S14p/S29e 9 60 2.2E-25 T 28-03-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS02015 7c2a9e36908dd1d90af9fed30a7a9063 61 Gene3D G3DSA:4.10.830.10 1 61 5.2E-23 T 28-03-2018 CU254_RS02015 7c2a9e36908dd1d90af9fed30a7a9063 61 Hamap MF_01364_B 30S ribosomal protein S14 type Z [rpsZ]. 1 61 25.579 T 28-03-2018 IPR023053 Ribosomal protein S14, type Z CU254_RS02015 7c2a9e36908dd1d90af9fed30a7a9063 61 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 45 - T 28-03-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS02015 7c2a9e36908dd1d90af9fed30a7a9063 61 SUPERFAMILY SSF57716 4 61 2.28E-21 T 28-03-2018 CU254_RS29575 58a0d0bcd9c0abde665c375416c55305 314 SUPERFAMILY SSF51569 10 298 1.88E-92 T 28-03-2018 CU254_RS29575 58a0d0bcd9c0abde665c375416c55305 314 Pfam PF00701 Dihydrodipicolinate synthetase family 10 287 6.5E-84 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CU254_RS29575 58a0d0bcd9c0abde665c375416c55305 314 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 142 173 - T 28-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 CU254_RS29575 58a0d0bcd9c0abde665c375416c55305 314 SMART SM01130 9 299 7.9E-115 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CU254_RS29575 58a0d0bcd9c0abde665c375416c55305 314 PIRSF PIRSF001365 7 303 5.2E-85 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CU254_RS29575 58a0d0bcd9c0abde665c375416c55305 314 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 13 290 8.2E-83 T 28-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CU254_RS29575 58a0d0bcd9c0abde665c375416c55305 314 Gene3D G3DSA:3.20.20.70 4 307 3.1E-94 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS29575 58a0d0bcd9c0abde665c375416c55305 314 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 9 298 51.877 T 28-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CU254_RS29575 58a0d0bcd9c0abde665c375416c55305 314 PRINTS PR00146 Dihydrodipicolinate synthase signature 137 154 2.5E-22 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CU254_RS29575 58a0d0bcd9c0abde665c375416c55305 314 PRINTS PR00146 Dihydrodipicolinate synthase signature 43 64 2.5E-22 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CU254_RS29575 58a0d0bcd9c0abde665c375416c55305 314 PRINTS PR00146 Dihydrodipicolinate synthase signature 79 97 2.5E-22 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CU254_RS29575 58a0d0bcd9c0abde665c375416c55305 314 PRINTS PR00146 Dihydrodipicolinate synthase signature 111 127 2.5E-22 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CU254_RS00140 4438d452e866f05f3d0a7264589a38c2 195 Pfam PF03029 Conserved hypothetical ATP binding protein 21 188 1.9E-26 T 28-03-2018 IPR004130 GPN-loop GTPase CU254_RS00140 4438d452e866f05f3d0a7264589a38c2 195 Gene3D G3DSA:3.40.50.300 4 192 1.3E-19 T 28-03-2018 CU254_RS00140 4438d452e866f05f3d0a7264589a38c2 195 SUPERFAMILY SSF52540 14 188 1.45E-21 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS28170 91c5aab80f3cfd76d9597640ad5a363d 541 Gene3D G3DSA:3.30.300.30 444 541 2.9E-27 T 28-03-2018 CU254_RS28170 91c5aab80f3cfd76d9597640ad5a363d 541 SUPERFAMILY SSF56801 55 540 9.94E-117 T 28-03-2018 CU254_RS28170 91c5aab80f3cfd76d9597640ad5a363d 541 Gene3D G3DSA:2.30.38.10 363 443 2.3E-11 T 28-03-2018 CU254_RS28170 91c5aab80f3cfd76d9597640ad5a363d 541 Pfam PF13193 AMP-binding enzyme C-terminal domain 459 534 1.3E-18 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS28170 91c5aab80f3cfd76d9597640ad5a363d 541 ProSitePatterns PS00455 Putative AMP-binding domain signature. 207 218 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS28170 91c5aab80f3cfd76d9597640ad5a363d 541 Gene3D G3DSA:3.40.50.980 215 362 4.5E-40 T 28-03-2018 CU254_RS28170 91c5aab80f3cfd76d9597640ad5a363d 541 Gene3D G3DSA:3.40.50.980 52 214 3.2E-24 T 28-03-2018 CU254_RS28170 91c5aab80f3cfd76d9597640ad5a363d 541 Pfam PF00501 AMP-binding enzyme 60 450 5.6E-63 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS42580 4aaaf0e702b1eb11ec42b7c70ec46597 249 Pfam PF13508 Acetyltransferase (GNAT) domain 149 213 1.7E-6 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS42580 4aaaf0e702b1eb11ec42b7c70ec46597 249 SUPERFAMILY SSF55729 78 113 2.84E-11 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS42580 4aaaf0e702b1eb11ec42b7c70ec46597 249 SUPERFAMILY SSF55729 23 41 2.84E-11 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS42580 4aaaf0e702b1eb11ec42b7c70ec46597 249 SUPERFAMILY SSF55729 142 216 2.84E-11 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS42580 4aaaf0e702b1eb11ec42b7c70ec46597 249 Gene3D G3DSA:3.40.630.30 9 227 6.6E-16 T 28-03-2018 CU254_RS36425 797d6ad0ac061213ddc6f2e1639bd758 143 Gene3D G3DSA:3.30.530.20 4 143 6.0E-27 T 28-03-2018 IPR023393 START-like domain CU254_RS36425 797d6ad0ac061213ddc6f2e1639bd758 143 SUPERFAMILY SSF55961 4 142 2.75E-30 T 28-03-2018 CU254_RS36425 797d6ad0ac061213ddc6f2e1639bd758 143 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 15 140 3.4E-22 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CU254_RS14030 293ff17321c1be619a22f4b5fe3b4d31 329 Gene3D G3DSA:3.40.190.10 188 260 3.6E-13 T 28-03-2018 CU254_RS14030 293ff17321c1be619a22f4b5fe3b4d31 329 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 81 308 8.1E-35 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CU254_RS14030 293ff17321c1be619a22f4b5fe3b4d31 329 Gene3D G3DSA:3.40.190.10 56 187 2.8E-19 T 28-03-2018 CU254_RS14030 293ff17321c1be619a22f4b5fe3b4d31 329 SUPERFAMILY SSF53850 68 310 1.28E-36 T 28-03-2018 CU254_RS14030 293ff17321c1be619a22f4b5fe3b4d31 329 SMART SM00062 73 311 3.1E-16 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CU254_RS33555 57a41cf62e9f33154017e9375f95a12a 244 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 178 3.7E-6 T 28-03-2018 CU254_RS33555 57a41cf62e9f33154017e9375f95a12a 244 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 240 4.5E-57 T 28-03-2018 CU254_RS33555 57a41cf62e9f33154017e9375f95a12a 244 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 134 162 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS33555 57a41cf62e9f33154017e9375f95a12a 244 SUPERFAMILY SSF51735 5 241 4.12E-73 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS33555 57a41cf62e9f33154017e9375f95a12a 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 2.3E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS33555 57a41cf62e9f33154017e9375f95a12a 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 2.3E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS33555 57a41cf62e9f33154017e9375f95a12a 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.3E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS33555 57a41cf62e9f33154017e9375f95a12a 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 2.3E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS33555 57a41cf62e9f33154017e9375f95a12a 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 2.3E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS33555 57a41cf62e9f33154017e9375f95a12a 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 2.3E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS33555 57a41cf62e9f33154017e9375f95a12a 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 1.8E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS33555 57a41cf62e9f33154017e9375f95a12a 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 128 136 1.8E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS33555 57a41cf62e9f33154017e9375f95a12a 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 166 1.8E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS33555 57a41cf62e9f33154017e9375f95a12a 244 Gene3D G3DSA:3.40.50.720 49 243 5.8E-58 T 28-03-2018 CU254_RS33555 57a41cf62e9f33154017e9375f95a12a 244 Gene3D G3DSA:3.40.50.720 1 48 1.8E-11 T 28-03-2018 CU254_RS20695 14f20b12de4411d50b4989908ed1f133 1042 Gene3D G3DSA:1.25.40.10 81 242 5.9E-21 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS20695 14f20b12de4411d50b4989908ed1f133 1042 Gene3D G3DSA:1.10.10.10 1 80 3.7E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS20695 14f20b12de4411d50b4989908ed1f133 1042 Gene3D G3DSA:3.40.50.300 243 389 8.7E-17 T 28-03-2018 CU254_RS20695 14f20b12de4411d50b4989908ed1f133 1042 Pfam PF00931 NB-ARC domain 258 454 9.8E-6 T 28-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 CU254_RS20695 14f20b12de4411d50b4989908ed1f133 1042 SUPERFAMILY SSF46894 6 78 5.39E-8 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS20695 14f20b12de4411d50b4989908ed1f133 1042 SUPERFAMILY SSF52540 240 510 1.15E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS20695 14f20b12de4411d50b4989908ed1f133 1042 PRINTS PR00364 Disease resistance protein signature 268 283 2.9E-6 T 28-03-2018 CU254_RS20695 14f20b12de4411d50b4989908ed1f133 1042 PRINTS PR00364 Disease resistance protein signature 444 458 2.9E-6 T 28-03-2018 CU254_RS20695 14f20b12de4411d50b4989908ed1f133 1042 PRINTS PR00364 Disease resistance protein signature 345 359 2.9E-6 T 28-03-2018 CU254_RS20695 14f20b12de4411d50b4989908ed1f133 1042 SMART SM01043 83 225 6.6E-47 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CU254_RS20695 14f20b12de4411d50b4989908ed1f133 1042 Pfam PF00486 Transcriptional regulatory protein, C terminal 13 67 1.6E-4 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS20695 14f20b12de4411d50b4989908ed1f133 1042 Gene3D G3DSA:1.25.40.10 614 865 9.6E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS20695 14f20b12de4411d50b4989908ed1f133 1042 SMART SM00862 6 78 4.8E-5 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS20695 14f20b12de4411d50b4989908ed1f133 1042 SUPERFAMILY SSF48452 710 893 3.48E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS20695 14f20b12de4411d50b4989908ed1f133 1042 Gene3D G3DSA:3.30.70.100 879 956 0.0014 T 28-03-2018 CU254_RS20695 14f20b12de4411d50b4989908ed1f133 1042 SUPERFAMILY SSF48452 83 245 3.7E-30 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS20695 14f20b12de4411d50b4989908ed1f133 1042 Pfam PF03704 Bacterial transcriptional activator domain 83 224 3.7E-37 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CU254_RS07725 b2232c8c7c530e21e551ea0e897a4a17 232 Gene3D G3DSA:1.10.10.10 123 232 3.3E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS07725 b2232c8c7c530e21e551ea0e897a4a17 232 Pfam PF00072 Response regulator receiver domain 9 117 2.5E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS07725 b2232c8c7c530e21e551ea0e897a4a17 232 SMART SM00448 7 117 6.5E-43 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS07725 b2232c8c7c530e21e551ea0e897a4a17 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 154 230 1.0E-21 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS07725 b2232c8c7c530e21e551ea0e897a4a17 232 Gene3D G3DSA:3.40.50.2300 1 122 2.0E-37 T 28-03-2018 CU254_RS07725 b2232c8c7c530e21e551ea0e897a4a17 232 SUPERFAMILY SSF52172 7 186 9.82E-41 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS07725 b2232c8c7c530e21e551ea0e897a4a17 232 SMART SM00862 154 230 2.9E-21 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS28015 5170d411f2b3123c1ce0e04188f72d4b 210 Gene3D G3DSA:3.40.50.150 16 204 7.3E-29 T 28-03-2018 CU254_RS28015 5170d411f2b3123c1ce0e04188f72d4b 210 Pfam PF08241 Methyltransferase domain 54 153 9.2E-16 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CU254_RS28015 5170d411f2b3123c1ce0e04188f72d4b 210 SUPERFAMILY SSF53335 41 201 4.3E-31 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS41685 f1e5115c7e23eecbec433706fec721ab 7285 Gene3D G3DSA:3.40.50.300 904 1245 9.4E-20 T 28-03-2018 CU254_RS41685 f1e5115c7e23eecbec433706fec721ab 7285 SUPERFAMILY SSF53335 57 254 1.3E-23 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS41685 f1e5115c7e23eecbec433706fec721ab 7285 Pfam PF04851 Type III restriction enzyme, res subunit 908 1041 3.5E-6 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CU254_RS41685 f1e5115c7e23eecbec433706fec721ab 7285 SUPERFAMILY SSF52540 1091 1180 9.02E-27 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS41685 f1e5115c7e23eecbec433706fec721ab 7285 SUPERFAMILY SSF52540 862 1027 9.02E-27 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS41685 f1e5115c7e23eecbec433706fec721ab 7285 SUPERFAMILY SSF56731 2644 2898 6.8E-40 T 28-03-2018 CU254_RS41685 f1e5115c7e23eecbec433706fec721ab 7285 Gene3D G3DSA:3.90.980.10 2639 2782 3.7E-31 T 28-03-2018 IPR013264 DNA primase, catalytic core, N-terminal CU254_RS41685 f1e5115c7e23eecbec433706fec721ab 7285 SMART SM00487 906 1178 6.5E-6 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CU254_RS41685 f1e5115c7e23eecbec433706fec721ab 7285 SUPERFAMILY SSF52540 1309 1476 2.15E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS41685 f1e5115c7e23eecbec433706fec721ab 7285 SUPERFAMILY SSF52540 1096 1171 2.15E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS41685 f1e5115c7e23eecbec433706fec721ab 7285 Gene3D G3DSA:3.40.1360.10 2783 2903 1.0E-9 T 28-03-2018 CU254_RS41685 f1e5115c7e23eecbec433706fec721ab 7285 SUPERFAMILY SSF47823 455 511 1.61E-7 T 28-03-2018 IPR010998 Integrase, Lambda-type, N-terminal CU254_RS41685 f1e5115c7e23eecbec433706fec721ab 7285 Gene3D G3DSA:3.40.50.150 67 336 2.1E-19 T 28-03-2018 CU254_RS41685 f1e5115c7e23eecbec433706fec721ab 7285 Pfam PF08275 DNA primase catalytic core, N-terminal domain 2687 2793 3.7E-24 T 28-03-2018 IPR013264 DNA primase, catalytic core, N-terminal CU254_RS41685 f1e5115c7e23eecbec433706fec721ab 7285 Gene3D G3DSA:3.40.50.300 1315 1472 1.3E-9 T 28-03-2018 CU254_RS34825 bb3bbe3a6b408e45dfc6df7f34d3c4ee 195 Gene3D G3DSA:1.10.357.10 76 195 1.0E-10 T 28-03-2018 CU254_RS34825 bb3bbe3a6b408e45dfc6df7f34d3c4ee 195 Gene3D G3DSA:1.10.10.60 1 49 1.1E-14 T 28-03-2018 CU254_RS34825 bb3bbe3a6b408e45dfc6df7f34d3c4ee 195 SUPERFAMILY SSF46689 5 88 1.15E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS34825 bb3bbe3a6b408e45dfc6df7f34d3c4ee 195 SUPERFAMILY SSF48498 105 192 5.48E-6 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS34825 bb3bbe3a6b408e45dfc6df7f34d3c4ee 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 60 2.1E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS34825 bb3bbe3a6b408e45dfc6df7f34d3c4ee 195 Gene3D G3DSA:1.10.10.60 50 75 1.3E-4 T 28-03-2018 CU254_RS03095 b85131a75e349dcbc161fa03ba0bda03 383 SUPERFAMILY SSF53756 2 379 1.73E-75 T 28-03-2018 CU254_RS03095 b85131a75e349dcbc161fa03ba0bda03 383 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 214 366 1.5E-36 T 28-03-2018 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 CU254_RS03095 b85131a75e349dcbc161fa03ba0bda03 383 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 268 363 7.0E-11 T 28-03-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 Reactome: R-HSA-156588 CU254_RS03095 b85131a75e349dcbc161fa03ba0bda03 383 Gene3D G3DSA:3.40.50.2000 1 205 2.6E-30 T 28-03-2018 CU254_RS03095 b85131a75e349dcbc161fa03ba0bda03 383 Gene3D G3DSA:3.40.50.2000 206 368 1.5E-39 T 28-03-2018 CU254_RS38275 0c37121f70277f69811cfd56c5c35113 704 Gene3D G3DSA:1.20.1250.20 249 501 4.9E-30 T 28-03-2018 CU254_RS38275 0c37121f70277f69811cfd56c5c35113 704 SUPERFAMILY SSF49464 524 594 2.67E-7 T 28-03-2018 IPR008969 Carboxypeptidase-like, regulatory domain CU254_RS38275 0c37121f70277f69811cfd56c5c35113 704 Gene3D G3DSA:2.60.40.10 520 600 7.1E-8 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS38275 0c37121f70277f69811cfd56c5c35113 704 Pfam PF13620 Carboxypeptidase regulatory-like domain 524 591 1.3E-8 T 28-03-2018 CU254_RS38275 0c37121f70277f69811cfd56c5c35113 704 Pfam PF13620 Carboxypeptidase regulatory-like domain 606 686 6.0E-14 T 28-03-2018 CU254_RS38275 0c37121f70277f69811cfd56c5c35113 704 Gene3D G3DSA:1.20.1250.20 7 198 2.0E-32 T 28-03-2018 CU254_RS38275 0c37121f70277f69811cfd56c5c35113 704 SUPERFAMILY SSF103473 8 197 5.75E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS38275 0c37121f70277f69811cfd56c5c35113 704 SUPERFAMILY SSF103473 462 496 5.75E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS38275 0c37121f70277f69811cfd56c5c35113 704 SUPERFAMILY SSF103473 246 417 5.75E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS38275 0c37121f70277f69811cfd56c5c35113 704 SUPERFAMILY SSF49452 601 686 1.49E-13 T 28-03-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 CU254_RS38275 0c37121f70277f69811cfd56c5c35113 704 Gene3D G3DSA:2.60.40.1120 601 688 1.9E-16 T 28-03-2018 CU254_RS38275 0c37121f70277f69811cfd56c5c35113 704 Pfam PF07690 Major Facilitator Superfamily 13 407 6.9E-43 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS31155 0eb8825ed7f6d0cfdc5d3b2ac0a11a87 250 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 1.3E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS31155 0eb8825ed7f6d0cfdc5d3b2ac0a11a87 250 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 1.3E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS31155 0eb8825ed7f6d0cfdc5d3b2ac0a11a87 250 SUPERFAMILY SSF48498 91 175 3.34E-9 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS31155 0eb8825ed7f6d0cfdc5d3b2ac0a11a87 250 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 68 5.2E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS31155 0eb8825ed7f6d0cfdc5d3b2ac0a11a87 250 Gene3D G3DSA:1.10.10.60 16 64 5.5E-18 T 28-03-2018 CU254_RS31155 0eb8825ed7f6d0cfdc5d3b2ac0a11a87 250 Gene3D G3DSA:1.10.357.10 65 206 4.9E-18 T 28-03-2018 CU254_RS31155 0eb8825ed7f6d0cfdc5d3b2ac0a11a87 250 SUPERFAMILY SSF46689 10 81 3.36E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS19560 6fd317fec4b1dcff7b5e1c09fda04c13 598 SUPERFAMILY SSF56112 77 188 7.36E-8 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS19560 6fd317fec4b1dcff7b5e1c09fda04c13 598 Gene3D G3DSA:2.130.10.120 285 387 1.5E-7 T 28-03-2018 CU254_RS19560 6fd317fec4b1dcff7b5e1c09fda04c13 598 Gene3D G3DSA:2.130.10.120 388 555 2.9E-18 T 28-03-2018 CU254_RS19560 6fd317fec4b1dcff7b5e1c09fda04c13 598 Gene3D G3DSA:2.130.10.120 556 597 1.4E-4 T 28-03-2018 CU254_RS19560 6fd317fec4b1dcff7b5e1c09fda04c13 598 Gene3D G3DSA:1.10.510.10 58 137 0.0019 T 28-03-2018 CU254_RS19560 6fd317fec4b1dcff7b5e1c09fda04c13 598 Gene3D G3DSA:1.10.510.10 146 271 0.0055 T 28-03-2018 CU254_RS19560 6fd317fec4b1dcff7b5e1c09fda04c13 598 SUPERFAMILY SSF82171 289 595 5.62E-30 T 28-03-2018 CU254_RS08035 53eb161a8243b850faa899f41d5e5891 327 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 96 321 5.3E-35 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS08035 53eb161a8243b850faa899f41d5e5891 327 Pfam PF04542 Sigma-70 region 2 99 171 4.6E-18 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS08035 53eb161a8243b850faa899f41d5e5891 327 SUPERFAMILY SSF88659 172 249 2.96E-13 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS08035 53eb161a8243b850faa899f41d5e5891 327 Gene3D G3DSA:1.10.10.10 244 326 1.3E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS08035 53eb161a8243b850faa899f41d5e5891 327 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 291 317 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS08035 53eb161a8243b850faa899f41d5e5891 327 Pfam PF04539 Sigma-70 region 3 182 255 5.2E-7 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS08035 53eb161a8243b850faa899f41d5e5891 327 Gene3D G3DSA:1.10.10.10 172 219 4.7E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS08035 53eb161a8243b850faa899f41d5e5891 327 SUPERFAMILY SSF88659 238 323 5.42E-22 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS08035 53eb161a8243b850faa899f41d5e5891 327 Gene3D G3DSA:1.10.1740.10 84 169 4.1E-22 T 28-03-2018 CU254_RS08035 53eb161a8243b850faa899f41d5e5891 327 TIGRFAM TIGR02479 FliA_WhiG: RNA polymerase sigma factor, FliA/WhiG family 99 322 2.1E-82 T 28-03-2018 IPR012845 RNA polymerase sigma factor, FliA/WhiG GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CU254_RS08035 53eb161a8243b850faa899f41d5e5891 327 PRINTS PR00046 Major sigma-70 factor signature 274 286 3.9E-13 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS08035 53eb161a8243b850faa899f41d5e5891 327 PRINTS PR00046 Major sigma-70 factor signature 291 306 3.9E-13 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS08035 53eb161a8243b850faa899f41d5e5891 327 PRINTS PR00046 Major sigma-70 factor signature 126 139 3.9E-13 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS08035 53eb161a8243b850faa899f41d5e5891 327 PRINTS PR00046 Major sigma-70 factor signature 306 317 3.9E-13 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS08035 53eb161a8243b850faa899f41d5e5891 327 Pfam PF04545 Sigma-70, region 4 270 319 8.2E-18 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS08035 53eb161a8243b850faa899f41d5e5891 327 SUPERFAMILY SSF88946 77 171 3.14E-28 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS08035 53eb161a8243b850faa899f41d5e5891 327 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 126 139 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS38485 cd0ceb0101cd9f498b82f277a4496ee4 609 SUPERFAMILY SSF101898 156 465 1.02E-29 T 28-03-2018 CU254_RS38485 cd0ceb0101cd9f498b82f277a4496ee4 609 Pfam PF01436 NHL repeat 401 428 4.5E-5 T 28-03-2018 IPR001258 NHL repeat GO:0005515 CU254_RS38485 cd0ceb0101cd9f498b82f277a4496ee4 609 Pfam PF01436 NHL repeat 167 194 4.5E-5 T 28-03-2018 IPR001258 NHL repeat GO:0005515 CU254_RS38485 cd0ceb0101cd9f498b82f277a4496ee4 609 SUPERFAMILY SSF52833 12 145 1.95E-29 T 28-03-2018 IPR012336 Thioredoxin-like fold CU254_RS38485 cd0ceb0101cd9f498b82f277a4496ee4 609 Gene3D G3DSA:2.120.10.30 335 485 1.7E-12 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CU254_RS38485 cd0ceb0101cd9f498b82f277a4496ee4 609 Gene3D G3DSA:2.120.10.30 145 327 6.1E-12 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CU254_RS38485 cd0ceb0101cd9f498b82f277a4496ee4 609 Gene3D G3DSA:3.40.30.10 2 144 2.7E-22 T 28-03-2018 CU254_RS38485 cd0ceb0101cd9f498b82f277a4496ee4 609 Pfam PF13905 Thioredoxin-like 26 120 4.2E-11 T 28-03-2018 IPR012336 Thioredoxin-like fold CU254_RS17480 3c5d235549cef122a2db8081f5433b1f 382 Gene3D G3DSA:3.40.50.2000 209 365 2.5E-25 T 28-03-2018 CU254_RS17480 3c5d235549cef122a2db8081f5433b1f 382 SUPERFAMILY SSF53756 1 381 1.04E-56 T 28-03-2018 CU254_RS17480 3c5d235549cef122a2db8081f5433b1f 382 Pfam PF06722 Protein of unknown function (DUF1205) 179 270 5.8E-11 T 28-03-2018 IPR010610 Domain of unknown function DUF1205 CU254_RS17480 3c5d235549cef122a2db8081f5433b1f 382 Gene3D G3DSA:3.40.50.2000 1 199 2.2E-25 T 28-03-2018 CU254_RS26615 de8ea67d99474c90760a7da8e38b6b23 245 Pfam PF01903 CbiX 134 229 4.8E-13 T 28-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 CU254_RS26615 de8ea67d99474c90760a7da8e38b6b23 245 Pfam PF01903 CbiX 10 113 1.2E-22 T 28-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 CU254_RS26615 de8ea67d99474c90760a7da8e38b6b23 245 Gene3D G3DSA:3.40.50.1400 2 108 3.3E-26 T 28-03-2018 CU254_RS26615 de8ea67d99474c90760a7da8e38b6b23 245 Gene3D G3DSA:3.40.50.1400 117 241 1.8E-21 T 28-03-2018 CU254_RS26615 de8ea67d99474c90760a7da8e38b6b23 245 SUPERFAMILY SSF53800 4 237 5.01E-39 T 28-03-2018 CU254_RS42100 cd06bddafe8309efb344142ba9806207 236 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 9.0E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS42100 cd06bddafe8309efb344142ba9806207 236 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 9.0E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS42100 cd06bddafe8309efb344142ba9806207 236 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 70 4.6E-18 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS42100 cd06bddafe8309efb344142ba9806207 236 SMART SM00345 15 76 6.8E-19 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS42100 cd06bddafe8309efb344142ba9806207 236 SUPERFAMILY SSF48008 102 230 1.78E-20 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS42100 cd06bddafe8309efb344142ba9806207 236 SMART SM00895 104 224 4.4E-15 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS42100 cd06bddafe8309efb344142ba9806207 236 SUPERFAMILY SSF46785 13 80 3.58E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS42100 cd06bddafe8309efb344142ba9806207 236 Pfam PF07729 FCD domain 105 223 6.4E-19 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS42100 cd06bddafe8309efb344142ba9806207 236 Gene3D G3DSA:1.10.10.10 5 78 9.2E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS42100 cd06bddafe8309efb344142ba9806207 236 Gene3D G3DSA:1.20.120.530 98 236 3.3E-23 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS18660 486ec4f58df4a24c877b57f686d7477a 216 Gene3D G3DSA:1.10.357.10 79 210 2.3E-5 T 28-03-2018 CU254_RS18660 486ec4f58df4a24c877b57f686d7477a 216 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 68 1.6E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS18660 486ec4f58df4a24c877b57f686d7477a 216 Gene3D G3DSA:1.10.10.60 56 78 1.1E-7 T 28-03-2018 CU254_RS18660 486ec4f58df4a24c877b57f686d7477a 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 1.4E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS18660 486ec4f58df4a24c877b57f686d7477a 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 1.4E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS18660 486ec4f58df4a24c877b57f686d7477a 216 Gene3D G3DSA:1.10.10.60 5 55 9.6E-19 T 28-03-2018 CU254_RS18660 486ec4f58df4a24c877b57f686d7477a 216 SUPERFAMILY SSF46689 12 87 3.18E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS03020 ba47981ce787845c2156502011a65f3e 514 Gene3D G3DSA:3.50.50.60 1 194 6.9E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS03020 ba47981ce787845c2156502011a65f3e 514 Gene3D G3DSA:3.50.50.60 195 366 7.8E-12 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS03020 ba47981ce787845c2156502011a65f3e 514 SUPERFAMILY SSF51905 5 49 5.4E-34 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS03020 ba47981ce787845c2156502011a65f3e 514 SUPERFAMILY SSF51905 86 347 5.4E-34 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS03020 ba47981ce787845c2156502011a65f3e 514 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 183 208 2.2E-5 T 28-03-2018 CU254_RS03020 ba47981ce787845c2156502011a65f3e 514 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 2.2E-5 T 28-03-2018 CU254_RS03020 ba47981ce787845c2156502011a65f3e 514 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 146 155 2.2E-5 T 28-03-2018 CU254_RS03020 ba47981ce787845c2156502011a65f3e 514 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 8 328 6.1E-55 T 28-03-2018 CU254_RS03020 ba47981ce787845c2156502011a65f3e 514 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 143 161 1.4E-9 T 28-03-2018 CU254_RS03020 ba47981ce787845c2156502011a65f3e 514 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 309 331 1.4E-9 T 28-03-2018 CU254_RS03020 ba47981ce787845c2156502011a65f3e 514 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 183 201 1.4E-9 T 28-03-2018 CU254_RS03020 ba47981ce787845c2156502011a65f3e 514 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.4E-9 T 28-03-2018 CU254_RS29105 bf112efcc2b111b165a56744a9913fb2 341 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 29 87 3.3E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS29105 bf112efcc2b111b165a56744a9913fb2 341 Gene3D G3DSA:3.40.190.10 202 284 5.3E-15 T 28-03-2018 CU254_RS29105 bf112efcc2b111b165a56744a9913fb2 341 Pfam PF03466 LysR substrate binding domain 113 315 7.7E-28 T 28-03-2018 IPR005119 LysR, substrate-binding CU254_RS29105 bf112efcc2b111b165a56744a9913fb2 341 SUPERFAMILY SSF46785 17 136 9.25E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS29105 bf112efcc2b111b165a56744a9913fb2 341 Gene3D G3DSA:3.40.190.10 114 201 1.2E-13 T 28-03-2018 CU254_RS29105 bf112efcc2b111b165a56744a9913fb2 341 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 7.9E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS29105 bf112efcc2b111b165a56744a9913fb2 341 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 53 63 7.9E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS29105 bf112efcc2b111b165a56744a9913fb2 341 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 63 74 7.9E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS29105 bf112efcc2b111b165a56744a9913fb2 341 SUPERFAMILY SSF53850 114 318 2.78E-26 T 28-03-2018 CU254_RS29105 bf112efcc2b111b165a56744a9913fb2 341 Gene3D G3DSA:1.10.10.10 12 113 2.5E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS10350 7dfaa6b1b7156f35fb041ee516dfc004 412 Gene3D G3DSA:3.40.50.1820 111 404 3.0E-44 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS10350 7dfaa6b1b7156f35fb041ee516dfc004 412 Pfam PF07859 alpha/beta hydrolase fold 168 377 2.1E-28 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CU254_RS10350 7dfaa6b1b7156f35fb041ee516dfc004 412 SUPERFAMILY SSF53474 130 380 1.12E-50 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS33020 859f0fcf90f76e302d964659d69a10b7 294 Gene3D G3DSA:1.25.10.10 91 148 6.5E-4 T 28-03-2018 IPR011989 Armadillo-like helical CU254_RS33020 859f0fcf90f76e302d964659d69a10b7 294 Gene3D G3DSA:2.160.20.80 149 267 2.5E-9 T 28-03-2018 CU254_RS32240 cce69569a1f3eec1326a7e9d26665243 412 Pfam PF12831 FAD dependent oxidoreductase 4 398 5.7E-79 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS32240 cce69569a1f3eec1326a7e9d26665243 412 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 353 360 9.7E-9 T 28-03-2018 CU254_RS32240 cce69569a1f3eec1326a7e9d26665243 412 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 157 166 9.7E-9 T 28-03-2018 CU254_RS32240 cce69569a1f3eec1326a7e9d26665243 412 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 9.7E-9 T 28-03-2018 CU254_RS32240 cce69569a1f3eec1326a7e9d26665243 412 Gene3D G3DSA:3.50.50.60 1 391 9.8E-22 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS32240 cce69569a1f3eec1326a7e9d26665243 412 SUPERFAMILY SSF51905 335 403 1.92E-22 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS32240 cce69569a1f3eec1326a7e9d26665243 412 SUPERFAMILY SSF51905 3 170 1.92E-22 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS08895 09698f3db319de702b8978014550fc2c 272 PIRSF PIRSF000007 1 272 1.2E-114 T 28-03-2018 IPR009152 Cytochrome bc1 complex, cytochrome c subunit GO:0005506|GO:0009055|GO:0016021|GO:0020037 CU254_RS08895 09698f3db319de702b8978014550fc2c 272 Gene3D G3DSA:1.10.760.10 144 234 7.9E-19 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CU254_RS08895 09698f3db319de702b8978014550fc2c 272 SUPERFAMILY SSF46626 18 138 4.36E-20 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CU254_RS08895 09698f3db319de702b8978014550fc2c 272 Gene3D G3DSA:1.10.760.10 37 143 6.2E-18 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CU254_RS08895 09698f3db319de702b8978014550fc2c 272 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 153 226 5.4E-14 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CU254_RS08895 09698f3db319de702b8978014550fc2c 272 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 57 132 9.2E-9 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CU254_RS08895 09698f3db319de702b8978014550fc2c 272 SUPERFAMILY SSF46626 138 228 1.83E-28 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CU254_RS30115 7100540f197f7d035e37c7eb73c54191 862 Gene3D G3DSA:1.25.40.10 609 762 1.4E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS30115 7100540f197f7d035e37c7eb73c54191 862 Gene3D G3DSA:1.25.40.10 488 608 7.4E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS30115 7100540f197f7d035e37c7eb73c54191 862 ProSitePatterns PS00622 LuxR-type HTH domain signature. 817 844 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS30115 7100540f197f7d035e37c7eb73c54191 862 SUPERFAMILY SSF52540 15 217 6.91E-6 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS30115 7100540f197f7d035e37c7eb73c54191 862 SUPERFAMILY SSF46894 793 854 1.56E-15 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS30115 7100540f197f7d035e37c7eb73c54191 862 SMART SM00421 800 857 9.2E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS30115 7100540f197f7d035e37c7eb73c54191 862 Pfam PF00196 Bacterial regulatory proteins, luxR family 802 854 2.0E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS30115 7100540f197f7d035e37c7eb73c54191 862 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 803 817 4.7E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS30115 7100540f197f7d035e37c7eb73c54191 862 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 817 833 4.7E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS30115 7100540f197f7d035e37c7eb73c54191 862 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 833 845 4.7E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS30115 7100540f197f7d035e37c7eb73c54191 862 Gene3D G3DSA:1.10.10.10 775 861 1.0E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS36055 7bd84e2627a01f38d18a0c370ed0cf35 203 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 197 4.8E-51 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CU254_RS36055 7bd84e2627a01f38d18a0c370ed0cf35 203 SMART SM00855 4 157 4.2E-19 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CU254_RS36055 7bd84e2627a01f38d18a0c370ed0cf35 203 SUPERFAMILY SSF53254 4 197 1.33E-51 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CU254_RS36055 7bd84e2627a01f38d18a0c370ed0cf35 203 PIRSF PIRSF000709 3 180 3.8E-7 T 28-03-2018 CU254_RS36055 7bd84e2627a01f38d18a0c370ed0cf35 203 Gene3D G3DSA:3.40.50.1240 3 199 1.6E-46 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CU254_RS10505 b446c389df5b7f9639ef88b37728ee9b 293 Gene3D G3DSA:3.40.50.720 2 170 1.2E-27 T 28-03-2018 CU254_RS10505 b446c389df5b7f9639ef88b37728ee9b 293 SUPERFAMILY SSF51735 7 160 1.61E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS10505 b446c389df5b7f9639ef88b37728ee9b 293 Gene3D G3DSA:1.10.1040.10 171 290 4.8E-22 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CU254_RS10505 b446c389df5b7f9639ef88b37728ee9b 293 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 10 23 - T 28-03-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 CU254_RS10505 b446c389df5b7f9639ef88b37728ee9b 293 SUPERFAMILY SSF48179 164 289 2.83E-24 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CU254_RS10505 b446c389df5b7f9639ef88b37728ee9b 293 PIRSF PIRSF000103 2 292 2.3E-68 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CU254_RS10505 b446c389df5b7f9639ef88b37728ee9b 293 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 7 156 4.3E-29 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CU254_RS10505 b446c389df5b7f9639ef88b37728ee9b 293 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 165 283 8.3E-18 T 28-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CU254_RS31375 dd5950be65d431133950255aea7854db 687 SUPERFAMILY SSF68912 34 73 5.49E-5 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 CU254_RS31375 dd5950be65d431133950255aea7854db 687 SMART SM00382 430 615 2.8E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS31375 dd5950be65d431133950255aea7854db 687 SMART SM00357 314 381 1.7E-7 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 CU254_RS31375 dd5950be65d431133950255aea7854db 687 SUPERFAMILY SSF52540 351 631 3.2E-66 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS31375 dd5950be65d431133950255aea7854db 687 Gene3D G3DSA:2.40.50.140 30 377 2.0E-42 T 28-03-2018 CU254_RS31375 dd5950be65d431133950255aea7854db 687 Pfam PF07497 Rho termination factor, RNA-binding domain 313 388 1.9E-29 T 28-03-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 CU254_RS31375 dd5950be65d431133950255aea7854db 687 SMART SM00959 33 75 4.5E-9 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 CU254_RS31375 dd5950be65d431133950255aea7854db 687 SUPERFAMILY SSF50249 313 388 1.54E-16 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CU254_RS31375 dd5950be65d431133950255aea7854db 687 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 419 623 6.0E-22 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CU254_RS31375 dd5950be65d431133950255aea7854db 687 TIGRFAM TIGR00767 rho: transcription termination factor Rho 33 677 9.6E-202 T 28-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 CU254_RS31375 dd5950be65d431133950255aea7854db 687 Hamap MF_01884 Transcription termination factor Rho [rho]. 306 679 201.031 T 28-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 CU254_RS31375 dd5950be65d431133950255aea7854db 687 Pfam PF07498 Rho termination factor, N-terminal domain 34 73 4.4E-10 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 CU254_RS31375 dd5950be65d431133950255aea7854db 687 Gene3D G3DSA:3.40.50.300 378 627 7.2E-53 T 28-03-2018 CU254_RS38520 cdec228d2724fbf0b43e8781d47e76db 257 SMART SM00382 29 226 6.6E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS38520 cdec228d2724fbf0b43e8781d47e76db 257 Gene3D G3DSA:3.40.50.300 1 254 5.0E-75 T 28-03-2018 CU254_RS38520 cdec228d2724fbf0b43e8781d47e76db 257 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS38520 cdec228d2724fbf0b43e8781d47e76db 257 SUPERFAMILY SSF52540 5 248 1.65E-79 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS38520 cdec228d2724fbf0b43e8781d47e76db 257 Pfam PF00005 ABC transporter 20 178 1.8E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS38520 cdec228d2724fbf0b43e8781d47e76db 257 PIRSF PIRSF039085 1 254 9.8E-124 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CU254_RS16130 ca542f672051900a8f6e2b47d75a0890 118 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 72 88 5.7E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS16130 ca542f672051900a8f6e2b47d75a0890 118 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 88 100 5.7E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS16130 ca542f672051900a8f6e2b47d75a0890 118 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 58 72 5.7E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS16130 ca542f672051900a8f6e2b47d75a0890 118 SMART SM00421 55 112 2.7E-21 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS16130 ca542f672051900a8f6e2b47d75a0890 118 Pfam PF00196 Bacterial regulatory proteins, luxR family 57 112 7.5E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS16130 ca542f672051900a8f6e2b47d75a0890 118 Gene3D G3DSA:1.10.10.10 55 118 1.6E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS16130 ca542f672051900a8f6e2b47d75a0890 118 SUPERFAMILY SSF46894 47 118 1.05E-21 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS18035 596e2b07d082a553a1910e0e247a2a71 132 SUPERFAMILY SSF54637 2 129 5.18E-36 T 28-03-2018 IPR029069 HotDog domain CU254_RS18035 596e2b07d082a553a1910e0e247a2a71 132 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 2 112 1.2E-20 T 28-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 CU254_RS18035 596e2b07d082a553a1910e0e247a2a71 132 Gene3D G3DSA:3.10.129.10 1 131 1.4E-33 T 28-03-2018 CU254_RS18035 596e2b07d082a553a1910e0e247a2a71 132 Pfam PF03061 Thioesterase superfamily 13 96 1.4E-16 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CU254_RS18035 596e2b07d082a553a1910e0e247a2a71 132 PIRSF PIRSF003230 1 132 1.0E-24 T 28-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 CU254_RS34200 5ba5e3e953acc0bfd65352085ed1d3e9 214 Gene3D G3DSA:3.90.550.10 1 214 3.5E-28 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS34200 5ba5e3e953acc0bfd65352085ed1d3e9 214 SUPERFAMILY SSF53448 1 192 1.69E-32 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS34200 5ba5e3e953acc0bfd65352085ed1d3e9 214 Pfam PF00535 Glycosyl transferase family 2 2 120 2.2E-19 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CU254_RS41375 c49f7c790d31efeb395101b897e6a741 489 Pfam PF01381 Helix-turn-helix 29 82 3.5E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS41375 c49f7c790d31efeb395101b897e6a741 489 Gene3D G3DSA:1.10.260.40 17 84 1.7E-15 T 28-03-2018 CU254_RS41375 c49f7c790d31efeb395101b897e6a741 489 SMART SM00530 26 82 5.4E-15 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS41375 c49f7c790d31efeb395101b897e6a741 489 SUPERFAMILY SSF47413 20 82 8.58E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS11060 c5d3f5111204c9c939303e5498ce17c4 238 Pfam PF00196 Bacterial regulatory proteins, luxR family 177 231 9.8E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS11060 c5d3f5111204c9c939303e5498ce17c4 238 ProSitePatterns PS00622 LuxR-type HTH domain signature. 191 218 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS11060 c5d3f5111204c9c939303e5498ce17c4 238 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 191 207 6.9E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS11060 c5d3f5111204c9c939303e5498ce17c4 238 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 207 219 6.9E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS11060 c5d3f5111204c9c939303e5498ce17c4 238 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 177 191 6.9E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS11060 c5d3f5111204c9c939303e5498ce17c4 238 SUPERFAMILY SSF46894 171 237 4.76E-20 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS11060 c5d3f5111204c9c939303e5498ce17c4 238 SMART SM00448 31 143 6.2E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS11060 c5d3f5111204c9c939303e5498ce17c4 238 Pfam PF00072 Response regulator receiver domain 33 136 3.8E-19 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS11060 c5d3f5111204c9c939303e5498ce17c4 238 Gene3D G3DSA:1.10.10.10 153 238 6.8E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS11060 c5d3f5111204c9c939303e5498ce17c4 238 Gene3D G3DSA:3.40.50.2300 30 152 4.2E-26 T 28-03-2018 CU254_RS11060 c5d3f5111204c9c939303e5498ce17c4 238 SUPERFAMILY SSF52172 32 154 1.71E-25 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS11060 c5d3f5111204c9c939303e5498ce17c4 238 SMART SM00421 174 231 2.4E-24 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS11585 bbe85170ac781e5ca5b54d500fa580fd 467 Pfam PF00245 Alkaline phosphatase 63 420 6.5E-109 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CU254_RS11585 bbe85170ac781e5ca5b54d500fa580fd 467 Gene3D G3DSA:3.40.720.10 22 467 4.1E-118 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CU254_RS11585 bbe85170ac781e5ca5b54d500fa580fd 467 PRINTS PR00113 Alkaline phosphatase signature 220 230 8.6E-37 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CU254_RS11585 bbe85170ac781e5ca5b54d500fa580fd 467 PRINTS PR00113 Alkaline phosphatase signature 315 344 8.6E-37 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CU254_RS11585 bbe85170ac781e5ca5b54d500fa580fd 467 PRINTS PR00113 Alkaline phosphatase signature 120 135 8.6E-37 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CU254_RS11585 bbe85170ac781e5ca5b54d500fa580fd 467 PRINTS PR00113 Alkaline phosphatase signature 63 83 8.6E-37 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CU254_RS11585 bbe85170ac781e5ca5b54d500fa580fd 467 PRINTS PR00113 Alkaline phosphatase signature 157 177 8.6E-37 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CU254_RS11585 bbe85170ac781e5ca5b54d500fa580fd 467 SMART SM00098 64 467 2.4E-160 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CU254_RS11585 bbe85170ac781e5ca5b54d500fa580fd 467 SUPERFAMILY SSF53649 53 466 4.25E-120 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CU254_RS11585 bbe85170ac781e5ca5b54d500fa580fd 467 ProSitePatterns PS00123 Alkaline phosphatase active site. 120 128 - T 28-03-2018 IPR018299 Alkaline phosphatase, active site GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CU254_RS37440 136f04e3e6dcbf54d5f22ff80077071c 306 SUPERFAMILY SSF161098 27 297 5.89E-30 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS37440 136f04e3e6dcbf54d5f22ff80077071c 306 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 5 303 2.1E-86 T 28-03-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 CU254_RS37440 136f04e3e6dcbf54d5f22ff80077071c 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 299 3.7E-13 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS37440 136f04e3e6dcbf54d5f22ff80077071c 306 Gene3D G3DSA:1.10.3720.10 11 303 3.8E-31 T 28-03-2018 CU254_RS12165 99671f6377a9ff9878671adb4dd980b5 211 PRINTS PR00155 Amicyanin family signature 94 109 2.5E-9 T 28-03-2018 IPR002386 Amicyanin/Pseudoazurin GO:0005507|GO:0009055 CU254_RS12165 99671f6377a9ff9878671adb4dd980b5 211 PRINTS PR00155 Amicyanin family signature 78 93 2.5E-9 T 28-03-2018 IPR002386 Amicyanin/Pseudoazurin GO:0005507|GO:0009055 CU254_RS12165 99671f6377a9ff9878671adb4dd980b5 211 PRINTS PR00155 Amicyanin family signature 38 57 2.5E-9 T 28-03-2018 IPR002386 Amicyanin/Pseudoazurin GO:0005507|GO:0009055 CU254_RS12165 99671f6377a9ff9878671adb4dd980b5 211 SUPERFAMILY SSF49503 12 109 1.79E-26 T 28-03-2018 IPR008972 Cupredoxin CU254_RS12165 99671f6377a9ff9878671adb4dd980b5 211 Gene3D G3DSA:2.60.40.420 24 139 1.5E-13 T 28-03-2018 IPR008972 Cupredoxin CU254_RS12165 99671f6377a9ff9878671adb4dd980b5 211 Pfam PF13473 Cupredoxin-like domain 7 109 7.4E-11 T 28-03-2018 IPR028096 EfeO-type cupredoxin-like domain CU254_RS08790 67f0de1bb7b36684a982f1d7edde9c9b 500 Gene3D G3DSA:3.40.220.10 2 167 3.4E-38 T 28-03-2018 CU254_RS08790 67f0de1bb7b36684a982f1d7edde9c9b 500 SUPERFAMILY SSF53187 178 496 5.65E-108 T 28-03-2018 CU254_RS08790 67f0de1bb7b36684a982f1d7edde9c9b 500 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 184 489 1.6E-115 T 28-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CU254_RS08790 67f0de1bb7b36684a982f1d7edde9c9b 500 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 29 147 3.8E-25 T 28-03-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CU254_RS08790 67f0de1bb7b36684a982f1d7edde9c9b 500 PRINTS PR00481 Cytosol aminopeptidase signature 318 339 9.0E-49 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CU254_RS08790 67f0de1bb7b36684a982f1d7edde9c9b 500 PRINTS PR00481 Cytosol aminopeptidase signature 340 360 9.0E-49 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CU254_RS08790 67f0de1bb7b36684a982f1d7edde9c9b 500 PRINTS PR00481 Cytosol aminopeptidase signature 259 276 9.0E-49 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CU254_RS08790 67f0de1bb7b36684a982f1d7edde9c9b 500 PRINTS PR00481 Cytosol aminopeptidase signature 368 383 9.0E-49 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CU254_RS08790 67f0de1bb7b36684a982f1d7edde9c9b 500 PRINTS PR00481 Cytosol aminopeptidase signature 281 302 9.0E-49 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CU254_RS08790 67f0de1bb7b36684a982f1d7edde9c9b 500 SUPERFAMILY SSF52949 22 163 3.41E-29 T 28-03-2018 CU254_RS08790 67f0de1bb7b36684a982f1d7edde9c9b 500 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 9 498 33.94 T 28-03-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 CU254_RS08790 67f0de1bb7b36684a982f1d7edde9c9b 500 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 344 351 - T 28-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CU254_RS08790 67f0de1bb7b36684a982f1d7edde9c9b 500 Gene3D G3DSA:3.40.630.10 168 500 1.6E-128 T 28-03-2018 CU254_RS23520 d11615c00068ddae3644b2fc4bfc241e 238 Pfam PF09339 IclR helix-turn-helix domain 3 40 1.5E-6 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS23520 d11615c00068ddae3644b2fc4bfc241e 238 Gene3D G3DSA:1.10.10.10 1 57 2.9E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS23520 d11615c00068ddae3644b2fc4bfc241e 238 Gene3D G3DSA:3.30.450.40 58 230 2.4E-40 T 28-03-2018 IPR029016 GAF domain-like CU254_RS23520 d11615c00068ddae3644b2fc4bfc241e 238 SMART SM00346 1 76 0.0075 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS23520 d11615c00068ddae3644b2fc4bfc241e 238 SUPERFAMILY SSF46785 3 59 2.1E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS23520 d11615c00068ddae3644b2fc4bfc241e 238 SUPERFAMILY SSF55781 45 229 1.77E-39 T 28-03-2018 IPR029016 GAF domain-like CU254_RS23520 d11615c00068ddae3644b2fc4bfc241e 238 Pfam PF01614 Bacterial transcriptional regulator 106 226 3.0E-29 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal CU254_RS34655 172e5041c25045fe181d8783462a2e34 227 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 10 66 4.5E-16 T 28-03-2018 IPR022687 DTXR-type HTH domain GO:0003677 CU254_RS34655 172e5041c25045fe181d8783462a2e34 227 Gene3D G3DSA:1.10.60.10 85 133 4.3E-22 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CU254_RS34655 172e5041c25045fe181d8783462a2e34 227 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 69 137 6.7E-29 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CU254_RS34655 172e5041c25045fe181d8783462a2e34 227 SUPERFAMILY SSF47979 69 142 7.98E-25 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CU254_RS34655 172e5041c25045fe181d8783462a2e34 227 Pfam PF04023 FeoA domain 151 225 2.9E-18 T 28-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CU254_RS34655 172e5041c25045fe181d8783462a2e34 227 SUPERFAMILY SSF46785 9 68 3.67E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS34655 172e5041c25045fe181d8783462a2e34 227 Gene3D G3DSA:1.10.10.10 3 84 1.5E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS34655 172e5041c25045fe181d8783462a2e34 227 SMART SM00529 30 129 3.4E-40 T 28-03-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 CU254_RS34655 172e5041c25045fe181d8783462a2e34 227 SMART SM00899 149 226 1.9E-17 T 28-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CU254_RS34655 172e5041c25045fe181d8783462a2e34 227 SUPERFAMILY SSF50037 151 225 9.61E-8 T 28-03-2018 IPR008988 Transcriptional repressor, C-terminal CU254_RS34655 172e5041c25045fe181d8783462a2e34 227 Gene3D G3DSA:2.30.30.90 152 226 2.0E-20 T 28-03-2018 CU254_RS31660 53b6b6c7ae02759e1e322c2c3732de4d 192 Pfam PF01381 Helix-turn-helix 14 68 4.5E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS31660 53b6b6c7ae02759e1e322c2c3732de4d 192 SUPERFAMILY SSF51182 81 176 3.6E-20 T 28-03-2018 IPR011051 RmlC-like cupin domain CU254_RS31660 53b6b6c7ae02759e1e322c2c3732de4d 192 Pfam PF07883 Cupin domain 116 176 4.1E-14 T 28-03-2018 IPR013096 Cupin 2, conserved barrel CU254_RS31660 53b6b6c7ae02759e1e322c2c3732de4d 192 SMART SM00530 13 68 8.2E-17 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS31660 53b6b6c7ae02759e1e322c2c3732de4d 192 Gene3D G3DSA:2.60.120.10 67 189 5.4E-21 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS31660 53b6b6c7ae02759e1e322c2c3732de4d 192 SUPERFAMILY SSF47413 9 73 5.91E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS31660 53b6b6c7ae02759e1e322c2c3732de4d 192 Gene3D G3DSA:1.10.260.40 1 66 5.2E-19 T 28-03-2018 CU254_RS38050 974c8bce95002de51e8551d41da15228 332 Gene3D G3DSA:3.10.20.30 248 330 2.8E-10 T 28-03-2018 IPR012675 Beta-grasp domain CU254_RS38050 974c8bce95002de51e8551d41da15228 332 SUPERFAMILY SSF54292 247 322 3.41E-14 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CU254_RS38050 974c8bce95002de51e8551d41da15228 332 SUPERFAMILY SSF63380 49 141 4.66E-23 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CU254_RS38050 974c8bce95002de51e8551d41da15228 332 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 301 309 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CU254_RS38050 974c8bce95002de51e8551d41da15228 332 PRINTS PR00409 Phthalate dioxygenase reductase family signature 177 186 9.8E-19 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CU254_RS38050 974c8bce95002de51e8551d41da15228 332 PRINTS PR00409 Phthalate dioxygenase reductase family signature 85 97 9.8E-19 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CU254_RS38050 974c8bce95002de51e8551d41da15228 332 PRINTS PR00409 Phthalate dioxygenase reductase family signature 226 234 9.8E-19 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CU254_RS38050 974c8bce95002de51e8551d41da15228 332 PRINTS PR00409 Phthalate dioxygenase reductase family signature 75 85 9.8E-19 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CU254_RS38050 974c8bce95002de51e8551d41da15228 332 PRINTS PR00409 Phthalate dioxygenase reductase family signature 152 171 9.8E-19 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CU254_RS38050 974c8bce95002de51e8551d41da15228 332 Gene3D G3DSA:2.40.30.10 44 142 8.8E-20 T 28-03-2018 CU254_RS38050 974c8bce95002de51e8551d41da15228 332 SUPERFAMILY SSF52343 139 261 9.43E-23 T 28-03-2018 CU254_RS38050 974c8bce95002de51e8551d41da15228 332 Gene3D G3DSA:3.40.50.80 147 247 1.6E-15 T 28-03-2018 CU254_RS38050 974c8bce95002de51e8551d41da15228 332 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 273 315 9.0E-7 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CU254_RS32145 832e63162c9307e79b5975156f887994 537 Pfam PF01039 Carboxyl transferase domain 50 526 9.6E-155 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 CU254_RS32145 832e63162c9307e79b5975156f887994 537 SUPERFAMILY SSF52096 27 273 1.04E-72 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS32145 832e63162c9307e79b5975156f887994 537 SUPERFAMILY SSF52096 239 519 3.06E-89 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS32145 832e63162c9307e79b5975156f887994 537 Gene3D G3DSA:3.90.226.10 275 532 2.0E-72 T 28-03-2018 CU254_RS32145 832e63162c9307e79b5975156f887994 537 Gene3D G3DSA:3.90.226.10 11 274 9.5E-68 T 28-03-2018 CU254_RS29715 373d2b5e11d997493acc6b87510e4462 244 Gene3D G3DSA:3.40.50.720 1 39 0.0051 T 28-03-2018 CU254_RS29715 373d2b5e11d997493acc6b87510e4462 244 SUPERFAMILY SSF51735 1 214 2.14E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS29715 373d2b5e11d997493acc6b87510e4462 244 Pfam PF13460 NAD(P)H-binding 7 173 2.8E-13 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS29715 373d2b5e11d997493acc6b87510e4462 244 Gene3D G3DSA:3.40.50.720 40 243 2.9E-14 T 28-03-2018 CU254_RS03570 d9255ffce48c3a4f8b4262e7a71d4644 117 SMART SM00345 17 76 1.2E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS03570 d9255ffce48c3a4f8b4262e7a71d4644 117 SUPERFAMILY SSF46785 6 84 1.02E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS03570 d9255ffce48c3a4f8b4262e7a71d4644 117 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 76 1.4E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS03570 d9255ffce48c3a4f8b4262e7a71d4644 117 Gene3D G3DSA:1.10.10.10 4 78 4.8E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS15970 fcf263c777eb7ffb47e65c1edcaeee4d 294 Pfam PF03466 LysR substrate binding domain 88 290 3.4E-32 T 28-03-2018 IPR005119 LysR, substrate-binding CU254_RS15970 fcf263c777eb7ffb47e65c1edcaeee4d 294 SUPERFAMILY SSF46785 1 83 7.71E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS15970 fcf263c777eb7ffb47e65c1edcaeee4d 294 Gene3D G3DSA:3.40.190.10 179 262 3.9E-13 T 28-03-2018 CU254_RS15970 fcf263c777eb7ffb47e65c1edcaeee4d 294 Gene3D G3DSA:3.40.190.10 88 178 2.9E-19 T 28-03-2018 CU254_RS15970 fcf263c777eb7ffb47e65c1edcaeee4d 294 Gene3D G3DSA:1.10.10.10 1 82 4.7E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS15970 fcf263c777eb7ffb47e65c1edcaeee4d 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.8E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS15970 fcf263c777eb7ffb47e65c1edcaeee4d 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.8E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS15970 fcf263c777eb7ffb47e65c1edcaeee4d 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.8E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS15970 fcf263c777eb7ffb47e65c1edcaeee4d 294 SUPERFAMILY SSF53850 88 291 2.85E-28 T 28-03-2018 CU254_RS15970 fcf263c777eb7ffb47e65c1edcaeee4d 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 8.1E-25 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS32380 b666e2dc7d08486ee78ee4647f17fe06 202 SUPERFAMILY SSF53474 2 198 1.3E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS32380 b666e2dc7d08486ee78ee4647f17fe06 202 Gene3D G3DSA:3.40.50.1820 23 197 5.9E-17 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS21690 71f2012d96eed7711e5e0eda235bd09c 410 Gene3D G3DSA:1.10.630.10 2 409 6.5E-83 T 28-03-2018 CU254_RS21690 71f2012d96eed7711e5e0eda235bd09c 410 PRINTS PR00359 B-class P450 signature 290 317 5.7E-44 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS21690 71f2012d96eed7711e5e0eda235bd09c 410 PRINTS PR00359 B-class P450 signature 273 284 5.7E-44 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS21690 71f2012d96eed7711e5e0eda235bd09c 410 PRINTS PR00359 B-class P450 signature 134 150 5.7E-44 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS21690 71f2012d96eed7711e5e0eda235bd09c 410 PRINTS PR00359 B-class P450 signature 192 214 5.7E-44 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS21690 71f2012d96eed7711e5e0eda235bd09c 410 PRINTS PR00359 B-class P450 signature 318 333 5.7E-44 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS21690 71f2012d96eed7711e5e0eda235bd09c 410 PRINTS PR00359 B-class P450 signature 349 360 5.7E-44 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS21690 71f2012d96eed7711e5e0eda235bd09c 410 PRINTS PR00359 B-class P450 signature 88 99 5.7E-44 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS21690 71f2012d96eed7711e5e0eda235bd09c 410 PRINTS PR00359 B-class P450 signature 151 166 5.7E-44 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS21690 71f2012d96eed7711e5e0eda235bd09c 410 PRINTS PR00359 B-class P450 signature 340 349 5.7E-44 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS21690 71f2012d96eed7711e5e0eda235bd09c 410 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 342 351 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CU254_RS21690 71f2012d96eed7711e5e0eda235bd09c 410 PRINTS PR00385 P450 superfamily signature 273 284 6.4E-10 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS21690 71f2012d96eed7711e5e0eda235bd09c 410 PRINTS PR00385 P450 superfamily signature 340 349 6.4E-10 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS21690 71f2012d96eed7711e5e0eda235bd09c 410 PRINTS PR00385 P450 superfamily signature 349 360 6.4E-10 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS21690 71f2012d96eed7711e5e0eda235bd09c 410 PRINTS PR00385 P450 superfamily signature 238 255 6.4E-10 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS21690 71f2012d96eed7711e5e0eda235bd09c 410 Pfam PF00067 Cytochrome P450 267 372 1.9E-22 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS21690 71f2012d96eed7711e5e0eda235bd09c 410 Pfam PF00067 Cytochrome P450 184 260 4.8E-10 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS21690 71f2012d96eed7711e5e0eda235bd09c 410 SUPERFAMILY SSF48264 37 400 4.06E-90 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS38860 5fe12a911bc820e9f9a6cb3e0db27963 406 Gene3D G3DSA:1.20.1250.20 3 201 1.1E-23 T 28-03-2018 CU254_RS38860 5fe12a911bc820e9f9a6cb3e0db27963 406 Gene3D G3DSA:1.20.1250.20 206 388 6.5E-22 T 28-03-2018 CU254_RS38860 5fe12a911bc820e9f9a6cb3e0db27963 406 PRINTS PR01035 Tetracycline resistance protein signature 29 45 2.1E-11 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CU254_RS38860 5fe12a911bc820e9f9a6cb3e0db27963 406 PRINTS PR01035 Tetracycline resistance protein signature 171 191 2.1E-11 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CU254_RS38860 5fe12a911bc820e9f9a6cb3e0db27963 406 PRINTS PR01035 Tetracycline resistance protein signature 143 165 2.1E-11 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CU254_RS38860 5fe12a911bc820e9f9a6cb3e0db27963 406 PRINTS PR01035 Tetracycline resistance protein signature 363 382 2.1E-11 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CU254_RS38860 5fe12a911bc820e9f9a6cb3e0db27963 406 SUPERFAMILY SSF103473 15 383 1.22E-57 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS38860 5fe12a911bc820e9f9a6cb3e0db27963 406 Pfam PF07690 Major Facilitator Superfamily 24 263 4.1E-28 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS08960 b3eb9a5e4b039bbc3bc48983cc8ab2a0 409 SUPERFAMILY SSF48264 8 405 9.04E-103 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS08960 b3eb9a5e4b039bbc3bc48983cc8ab2a0 409 Gene3D G3DSA:1.10.630.10 3 407 7.2E-84 T 28-03-2018 CU254_RS08960 b3eb9a5e4b039bbc3bc48983cc8ab2a0 409 Pfam PF00067 Cytochrome P450 201 376 6.2E-23 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS08960 b3eb9a5e4b039bbc3bc48983cc8ab2a0 409 Pfam PF00067 Cytochrome P450 90 204 2.5E-5 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS08960 b3eb9a5e4b039bbc3bc48983cc8ab2a0 409 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 348 357 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CU254_RS08960 b3eb9a5e4b039bbc3bc48983cc8ab2a0 409 PRINTS PR00359 B-class P450 signature 161 176 1.5E-57 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS08960 b3eb9a5e4b039bbc3bc48983cc8ab2a0 409 PRINTS PR00359 B-class P450 signature 198 220 1.5E-57 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS08960 b3eb9a5e4b039bbc3bc48983cc8ab2a0 409 PRINTS PR00359 B-class P450 signature 297 324 1.5E-57 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS08960 b3eb9a5e4b039bbc3bc48983cc8ab2a0 409 PRINTS PR00359 B-class P450 signature 98 109 1.5E-57 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS08960 b3eb9a5e4b039bbc3bc48983cc8ab2a0 409 PRINTS PR00359 B-class P450 signature 144 160 1.5E-57 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS08960 b3eb9a5e4b039bbc3bc48983cc8ab2a0 409 PRINTS PR00359 B-class P450 signature 325 340 1.5E-57 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS08960 b3eb9a5e4b039bbc3bc48983cc8ab2a0 409 PRINTS PR00359 B-class P450 signature 346 355 1.5E-57 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS08960 b3eb9a5e4b039bbc3bc48983cc8ab2a0 409 PRINTS PR00359 B-class P450 signature 279 290 1.5E-57 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS08960 b3eb9a5e4b039bbc3bc48983cc8ab2a0 409 PRINTS PR00359 B-class P450 signature 355 366 1.5E-57 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS23450 1dacecb5ae2f56447703bec0c8a20d12 381 Gene3D G3DSA:3.90.380.10 132 344 4.8E-36 T 28-03-2018 CU254_RS23450 1dacecb5ae2f56447703bec0c8a20d12 381 SUPERFAMILY SSF50022 19 131 1.7E-30 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CU254_RS23450 1dacecb5ae2f56447703bec0c8a20d12 381 Pfam PF00355 Rieske [2Fe-2S] domain 25 108 5.3E-18 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CU254_RS23450 1dacecb5ae2f56447703bec0c8a20d12 381 SUPERFAMILY SSF55961 123 340 4.24E-33 T 28-03-2018 CU254_RS23450 1dacecb5ae2f56447703bec0c8a20d12 381 Gene3D G3DSA:2.102.10.10 18 131 2.7E-28 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CU254_RS09135 b339782199b6b773140a23b8f7fdc8bf 255 Gene3D G3DSA:1.10.1660.10 1 58 8.5E-19 T 28-03-2018 CU254_RS09135 b339782199b6b773140a23b8f7fdc8bf 255 SUPERFAMILY SSF46955 2 99 3.63E-22 T 28-03-2018 IPR009061 Putative DNA-binding domain CU254_RS09135 b339782199b6b773140a23b8f7fdc8bf 255 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 14 27 9.6E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS09135 b339782199b6b773140a23b8f7fdc8bf 255 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 3 14 9.6E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS09135 b339782199b6b773140a23b8f7fdc8bf 255 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 38 58 9.6E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS09135 b339782199b6b773140a23b8f7fdc8bf 255 SMART SM00422 2 71 6.6E-17 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS09135 b339782199b6b773140a23b8f7fdc8bf 255 Gene3D G3DSA:1.10.1660.10 59 105 3.6E-4 T 28-03-2018 CU254_RS09135 b339782199b6b773140a23b8f7fdc8bf 255 Pfam PF00376 MerR family regulatory protein 3 40 2.2E-14 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS18530 c94343a7f6ec63b06c6682a4e307c0d5 514 SUPERFAMILY SSF56801 3 507 1.31E-146 T 28-03-2018 CU254_RS18530 c94343a7f6ec63b06c6682a4e307c0d5 514 ProSitePatterns PS00455 Putative AMP-binding domain signature. 160 171 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS18530 c94343a7f6ec63b06c6682a4e307c0d5 514 Gene3D G3DSA:3.30.300.30 408 512 1.4E-30 T 28-03-2018 CU254_RS18530 c94343a7f6ec63b06c6682a4e307c0d5 514 Gene3D G3DSA:3.40.50.980 2 165 3.4E-37 T 28-03-2018 CU254_RS18530 c94343a7f6ec63b06c6682a4e307c0d5 514 Gene3D G3DSA:3.40.50.980 166 319 3.7E-35 T 28-03-2018 CU254_RS18530 c94343a7f6ec63b06c6682a4e307c0d5 514 Gene3D G3DSA:2.30.38.10 320 406 3.1E-26 T 28-03-2018 CU254_RS18530 c94343a7f6ec63b06c6682a4e307c0d5 514 Pfam PF00501 AMP-binding enzyme 13 413 1.0E-96 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS18530 c94343a7f6ec63b06c6682a4e307c0d5 514 Pfam PF13193 AMP-binding enzyme C-terminal domain 422 495 3.4E-22 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS39245 01086978291bd5858dcf6ccbf8cdc946 296 Gene3D G3DSA:1.10.1040.10 165 295 1.3E-38 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CU254_RS39245 01086978291bd5858dcf6ccbf8cdc946 296 TIGRFAM TIGR00872 gnd_rel: 6-phosphogluconate dehydrogenase (decarboxylating) 3 294 9.6E-106 T 28-03-2018 IPR004849 6-phosphogluconate dehydrogenase, YqeC-type GO:0055114 CU254_RS39245 01086978291bd5858dcf6ccbf8cdc946 296 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 163 274 1.2E-21 T 28-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CU254_RS39245 01086978291bd5858dcf6ccbf8cdc946 296 SUPERFAMILY SSF48179 161 293 3.2E-39 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CU254_RS39245 01086978291bd5858dcf6ccbf8cdc946 296 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 231 243 - T 28-03-2018 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CU254_RS39245 01086978291bd5858dcf6ccbf8cdc946 296 SMART SM01350 163 296 0.0013 T 28-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CU254_RS39245 01086978291bd5858dcf6ccbf8cdc946 296 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 2 25 5.5E-17 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CU254_RS39245 01086978291bd5858dcf6ccbf8cdc946 296 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 152 180 5.5E-17 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CU254_RS39245 01086978291bd5858dcf6ccbf8cdc946 296 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 227 254 5.5E-17 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CU254_RS39245 01086978291bd5858dcf6ccbf8cdc946 296 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 144 2.6E-34 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CU254_RS39245 01086978291bd5858dcf6ccbf8cdc946 296 SUPERFAMILY SSF51735 3 145 6.31E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS39245 01086978291bd5858dcf6ccbf8cdc946 296 Gene3D G3DSA:3.40.50.720 3 164 3.2E-30 T 28-03-2018 CU254_RS12750 34978bd7d97480308280f5825dc4fff8 553 SUPERFAMILY SSF102114 183 409 1.1E-24 T 28-03-2018 CU254_RS12750 34978bd7d97480308280f5825dc4fff8 553 Gene3D G3DSA:3.40.50.280 12 142 5.2E-13 T 28-03-2018 CU254_RS12750 34978bd7d97480308280f5825dc4fff8 553 Gene3D G3DSA:3.20.20.70 186 456 2.2E-25 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS12750 34978bd7d97480308280f5825dc4fff8 553 Pfam PF04055 Radical SAM superfamily 215 383 3.3E-13 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CU254_RS12750 34978bd7d97480308280f5825dc4fff8 553 SMART SM00729 207 433 1.3E-9 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CU254_RS12750 34978bd7d97480308280f5825dc4fff8 553 Pfam PF02310 B12 binding domain 18 137 4.1E-9 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CU254_RS12750 34978bd7d97480308280f5825dc4fff8 553 TIGRFAM TIGR04428 B12_rSAM_trp_MT: tryptophan 2-C-methyltransferase 6 550 0.0 T 28-03-2018 IPR030969 Tryptophan 2-C-methyltransferase KEGG: 00270+2.1.1.10|MetaCyc: PWY-5441|MetaCyc: PWY-702 CU254_RS40680 bfa1595429e770d9bba9dd58652f99ef 784 Pfam PF00005 ABC transporter 569 715 3.2E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS40680 bfa1595429e770d9bba9dd58652f99ef 784 SUPERFAMILY SSF52540 545 781 1.87E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS40680 bfa1595429e770d9bba9dd58652f99ef 784 Gene3D G3DSA:3.90.70.10 88 230 1.6E-23 T 28-03-2018 CU254_RS40680 bfa1595429e770d9bba9dd58652f99ef 784 SMART SM00382 576 768 2.1E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS40680 bfa1595429e770d9bba9dd58652f99ef 784 SUPERFAMILY SSF90123 238 504 2.22E-27 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CU254_RS40680 bfa1595429e770d9bba9dd58652f99ef 784 Pfam PF00664 ABC transporter transmembrane region 284 490 1.0E-16 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CU254_RS40680 bfa1595429e770d9bba9dd58652f99ef 784 ProSitePatterns PS00211 ABC transporters family signature. 687 701 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS40680 bfa1595429e770d9bba9dd58652f99ef 784 Gene3D G3DSA:1.20.1560.10 231 509 3.3E-20 T 28-03-2018 CU254_RS40680 bfa1595429e770d9bba9dd58652f99ef 784 Pfam PF03412 Peptidase C39 family 91 221 3.4E-20 T 28-03-2018 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 CU254_RS40680 bfa1595429e770d9bba9dd58652f99ef 784 Gene3D G3DSA:3.40.50.300 549 781 5.1E-58 T 28-03-2018 CU254_RS25340 1c46e421386237feb747592052c572be 237 SUPERFAMILY SSF53474 7 235 1.09E-27 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS25340 1c46e421386237feb747592052c572be 237 Pfam PF12697 Alpha/beta hydrolase family 12 231 2.3E-14 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS25340 1c46e421386237feb747592052c572be 237 Gene3D G3DSA:3.40.50.1820 4 236 3.2E-22 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS25035 ed0ad83541051fb7c00c333594706d3a 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.3E-5 T 28-03-2018 CU254_RS25035 ed0ad83541051fb7c00c333594706d3a 468 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 415 437 1.3E-5 T 28-03-2018 CU254_RS25035 ed0ad83541051fb7c00c333594706d3a 468 SUPERFAMILY SSF51905 4 259 1.5E-44 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS25035 ed0ad83541051fb7c00c333594706d3a 468 SUPERFAMILY SSF51905 410 468 1.5E-44 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS25035 ed0ad83541051fb7c00c333594706d3a 468 Gene3D G3DSA:3.90.700.10 278 400 2.3E-30 T 28-03-2018 CU254_RS25035 ed0ad83541051fb7c00c333594706d3a 468 Gene3D G3DSA:3.50.50.60 1 277 8.7E-38 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS25035 ed0ad83541051fb7c00c333594706d3a 468 Pfam PF00890 FAD binding domain 7 451 2.7E-58 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CU254_RS25035 ed0ad83541051fb7c00c333594706d3a 468 SUPERFAMILY SSF56425 248 403 2.2E-26 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CU254_RS20435 fd3e09d6e7534a732dabf50dae66d53e 234 Gene3D G3DSA:3.40.50.300 1 216 9.2E-59 T 28-03-2018 CU254_RS20435 fd3e09d6e7534a732dabf50dae66d53e 234 SMART SM00382 30 197 3.1E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS20435 fd3e09d6e7534a732dabf50dae66d53e 234 ProSitePatterns PS00211 ABC transporters family signature. 120 134 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS20435 fd3e09d6e7534a732dabf50dae66d53e 234 SUPERFAMILY SSF52540 2 201 2.38E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS20435 fd3e09d6e7534a732dabf50dae66d53e 234 Pfam PF00005 ABC transporter 21 147 5.7E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS17525 be8fe621d5b01d72599337030707521b 602 SUPERFAMILY SSF63829 92 155 5.23E-9 T 28-03-2018 CU254_RS17525 be8fe621d5b01d72599337030707521b 602 SUPERFAMILY SSF63829 8 64 5.23E-9 T 28-03-2018 CU254_RS17525 be8fe621d5b01d72599337030707521b 602 Pfam PF01436 NHL repeat 433 460 4.3E-7 T 28-03-2018 IPR001258 NHL repeat GO:0005515 CU254_RS17525 be8fe621d5b01d72599337030707521b 602 Pfam PF01436 NHL repeat 244 266 3.9E-7 T 28-03-2018 IPR001258 NHL repeat GO:0005515 CU254_RS17525 be8fe621d5b01d72599337030707521b 602 Pfam PF01436 NHL repeat 192 219 3.5E-6 T 28-03-2018 IPR001258 NHL repeat GO:0005515 CU254_RS17525 be8fe621d5b01d72599337030707521b 602 SUPERFAMILY SSF63825 167 416 9.68E-34 T 28-03-2018 CU254_RS17525 be8fe621d5b01d72599337030707521b 602 SUPERFAMILY SSF101898 337 600 5.93E-40 T 28-03-2018 CU254_RS17525 be8fe621d5b01d72599337030707521b 602 Gene3D G3DSA:2.120.10.30 184 281 2.4E-18 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CU254_RS17525 be8fe621d5b01d72599337030707521b 602 Gene3D G3DSA:2.120.10.30 380 477 3.1E-17 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CU254_RS17525 be8fe621d5b01d72599337030707521b 602 Gene3D G3DSA:2.120.10.30 67 183 8.9E-7 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CU254_RS17525 be8fe621d5b01d72599337030707521b 602 Gene3D G3DSA:2.120.10.30 478 601 5.8E-20 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CU254_RS17525 be8fe621d5b01d72599337030707521b 602 Gene3D G3DSA:2.120.10.30 282 379 2.9E-16 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CU254_RS17525 be8fe621d5b01d72599337030707521b 602 Gene3D G3DSA:2.120.10.30 2 66 0.054 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CU254_RS36575 c64d9ca2b90fcd14d0cb0f466dabbb8e 309 Pfam PF13580 SIS domain 53 166 1.4E-7 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CU254_RS36575 c64d9ca2b90fcd14d0cb0f466dabbb8e 309 ProSitePatterns PS01272 Glucokinase regulatory protein family signature. 191 208 - T 28-03-2018 IPR005486 Glucokinase regulatory protein, conserved site KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126|Reactome: R-HSA-170822|Reactome: R-HSA-5619107 CU254_RS36575 c64d9ca2b90fcd14d0cb0f466dabbb8e 309 Hamap MF_00068 N-acetylmuramic acid 6-phosphate etherase [murQ]. 9 301 35.85 T 28-03-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 CU254_RS36575 c64d9ca2b90fcd14d0cb0f466dabbb8e 309 Gene3D G3DSA:1.10.8.10 247 277 3.2E-8 T 28-03-2018 CU254_RS36575 c64d9ca2b90fcd14d0cb0f466dabbb8e 309 SUPERFAMILY SSF46934 243 277 1.34E-5 T 28-03-2018 IPR009060 UBA-like GO:0005515 CU254_RS36575 c64d9ca2b90fcd14d0cb0f466dabbb8e 309 SUPERFAMILY SSF53697 15 254 2.43E-61 T 28-03-2018 CU254_RS36575 c64d9ca2b90fcd14d0cb0f466dabbb8e 309 Gene3D G3DSA:3.40.50.10490 19 246 9.5E-43 T 28-03-2018 CU254_RS15435 8d8cef4931d61cb9962533aad07ab59a 983 Gene3D G3DSA:3.30.465.10 114 304 5.8E-36 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CU254_RS15435 8d8cef4931d61cb9962533aad07ab59a 983 Pfam PF02913 FAD linked oxidases, C-terminal domain 286 530 7.5E-41 T 28-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CU254_RS15435 8d8cef4931d61cb9962533aad07ab59a 983 Pfam PF02754 Cysteine-rich domain 756 828 0.047 T 28-03-2018 IPR004017 Cysteine-rich domain CU254_RS15435 8d8cef4931d61cb9962533aad07ab59a 983 Pfam PF13183 4Fe-4S dicluster domain 569 652 1.0E-9 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CU254_RS15435 8d8cef4931d61cb9962533aad07ab59a 983 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 638 649 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CU254_RS15435 8d8cef4931d61cb9962533aad07ab59a 983 Gene3D G3DSA:1.10.45.10 491 530 4.6E-9 T 28-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CU254_RS15435 8d8cef4931d61cb9962533aad07ab59a 983 SUPERFAMILY SSF55103 286 540 3.27E-46 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CU254_RS15435 8d8cef4931d61cb9962533aad07ab59a 983 Gene3D G3DSA:3.30.43.10 9 107 2.3E-16 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CU254_RS15435 8d8cef4931d61cb9962533aad07ab59a 983 Gene3D G3DSA:1.10.1060.10 557 671 6.3E-16 T 28-03-2018 CU254_RS15435 8d8cef4931d61cb9962533aad07ab59a 983 SUPERFAMILY SSF46548 567 656 1.31E-7 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CU254_RS15435 8d8cef4931d61cb9962533aad07ab59a 983 Pfam PF01565 FAD binding domain 57 195 1.4E-36 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CU254_RS15435 8d8cef4931d61cb9962533aad07ab59a 983 SUPERFAMILY SSF56176 23 280 3.16E-49 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CU254_RS18535 f6021a16d5ad25338082fec6d95b624a 395 Gene3D G3DSA:1.20.140.10 231 395 6.6E-43 T 28-03-2018 CU254_RS18535 f6021a16d5ad25338082fec6d95b624a 395 Gene3D G3DSA:1.10.540.10 5 136 5.9E-20 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS18535 f6021a16d5ad25338082fec6d95b624a 395 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 18 132 1.1E-14 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS18535 f6021a16d5ad25338082fec6d95b624a 395 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 136 217 9.2E-17 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CU254_RS18535 f6021a16d5ad25338082fec6d95b624a 395 SUPERFAMILY SSF56645 11 248 3.66E-50 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS18535 f6021a16d5ad25338082fec6d95b624a 395 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 240 389 2.5E-40 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS18535 f6021a16d5ad25338082fec6d95b624a 395 PIRSF PIRSF016578 40 92 0.034 T 28-03-2018 CU254_RS18535 f6021a16d5ad25338082fec6d95b624a 395 PIRSF PIRSF016578 247 379 4.5E-5 T 28-03-2018 CU254_RS18535 f6021a16d5ad25338082fec6d95b624a 395 PIRSF PIRSF016578 138 206 0.0069 T 28-03-2018 CU254_RS18535 f6021a16d5ad25338082fec6d95b624a 395 Gene3D G3DSA:2.40.110.10 137 230 3.4E-26 T 28-03-2018 CU254_RS18535 f6021a16d5ad25338082fec6d95b624a 395 SUPERFAMILY SSF47203 239 390 5.8E-42 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS13580 4faaf7f11f712897ca6b0f11c34a4c87 280 SUPERFAMILY SSF48179 184 280 7.23E-28 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CU254_RS13580 4faaf7f11f712897ca6b0f11c34a4c87 280 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 4 181 9.1E-57 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CU254_RS13580 4faaf7f11f712897ca6b0f11c34a4c87 280 PIRSF PIRSF000105 1 280 2.3E-76 T 28-03-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 CU254_RS13580 4faaf7f11f712897ca6b0f11c34a4c87 280 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 184 280 4.1E-29 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CU254_RS13580 4faaf7f11f712897ca6b0f11c34a4c87 280 SUPERFAMILY SSF51735 4 181 1.74E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS13580 4faaf7f11f712897ca6b0f11c34a4c87 280 Gene3D G3DSA:1.10.1040.10 183 280 1.0E-29 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CU254_RS13580 4faaf7f11f712897ca6b0f11c34a4c87 280 Gene3D G3DSA:3.40.50.720 3 182 7.5E-45 T 28-03-2018 CU254_RS36135 868e2a0548b1aa97204270f5ff87011f 291 Gene3D G3DSA:1.10.340.30 18 115 2.1E-27 T 28-03-2018 CU254_RS36135 868e2a0548b1aa97204270f5ff87011f 291 Pfam PF00633 Helix-hairpin-helix motif 98 126 6.5E-7 T 28-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 CU254_RS36135 868e2a0548b1aa97204270f5ff87011f 291 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 33 146 4.4E-14 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CU254_RS36135 868e2a0548b1aa97204270f5ff87011f 291 SUPERFAMILY SSF48150 6 216 1.26E-61 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CU254_RS36135 868e2a0548b1aa97204270f5ff87011f 291 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 191 207 1.6E-4 T 28-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 CU254_RS36135 868e2a0548b1aa97204270f5ff87011f 291 Gene3D G3DSA:1.10.1670.10 116 222 4.5E-32 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CU254_RS36135 868e2a0548b1aa97204270f5ff87011f 291 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 191 207 - T 28-03-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CU254_RS36135 868e2a0548b1aa97204270f5ff87011f 291 SMART SM00478 37 189 1.6E-37 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CU254_RS24480 333862d1ee245f2050c69cce95d14d6c 262 SMART SM00418 12 87 4.6E-17 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS24480 333862d1ee245f2050c69cce95d14d6c 262 Gene3D G3DSA:1.10.10.10 1 150 2.4E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS24480 333862d1ee245f2050c69cce95d14d6c 262 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 44 59 2.0E-7 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS24480 333862d1ee245f2050c69cce95d14d6c 262 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 11 26 2.0E-7 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS24480 333862d1ee245f2050c69cce95d14d6c 262 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 59 74 2.0E-7 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS24480 333862d1ee245f2050c69cce95d14d6c 262 Gene3D G3DSA:1.10.10.10 151 243 0.087 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS24480 333862d1ee245f2050c69cce95d14d6c 262 SUPERFAMILY SSF46785 6 119 1.39E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS24480 333862d1ee245f2050c69cce95d14d6c 262 Pfam PF12840 Helix-turn-helix domain 10 68 1.4E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS32170 a3075214c6b953acf5cf2ff6b76070de 435 Gene3D G3DSA:3.90.1150.10 297 435 9.4E-51 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS32170 a3075214c6b953acf5cf2ff6b76070de 435 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 11 428 4.4E-142 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CU254_RS32170 a3075214c6b953acf5cf2ff6b76070de 435 PIRSF PIRSF001434 1 432 4.6E-133 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CU254_RS32170 a3075214c6b953acf5cf2ff6b76070de 435 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 10 428 9.2E-198 T 28-03-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 CU254_RS32170 a3075214c6b953acf5cf2ff6b76070de 435 Gene3D G3DSA:3.40.640.10 8 295 1.5E-61 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS32170 a3075214c6b953acf5cf2ff6b76070de 435 SUPERFAMILY SSF53383 8 428 1.99E-122 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS32170 a3075214c6b953acf5cf2ff6b76070de 435 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 204 218 - T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CU254_RS08380 4de7a52ad12eddf191a07f2039b80700 222 Gene3D G3DSA:1.10.10.10 2 74 1.3E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS08380 4de7a52ad12eddf191a07f2039b80700 222 SMART SM00895 92 214 9.6E-18 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS08380 4de7a52ad12eddf191a07f2039b80700 222 SUPERFAMILY SSF48008 89 217 7.85E-23 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS08380 4de7a52ad12eddf191a07f2039b80700 222 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 72 5.6E-19 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS08380 4de7a52ad12eddf191a07f2039b80700 222 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 62 3.9E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS08380 4de7a52ad12eddf191a07f2039b80700 222 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 32 46 3.9E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS08380 4de7a52ad12eddf191a07f2039b80700 222 SMART SM00345 13 72 4.6E-18 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS08380 4de7a52ad12eddf191a07f2039b80700 222 Gene3D G3DSA:1.20.120.530 75 222 5.3E-23 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS08380 4de7a52ad12eddf191a07f2039b80700 222 Pfam PF07729 FCD domain 92 208 1.8E-21 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS08380 4de7a52ad12eddf191a07f2039b80700 222 SUPERFAMILY SSF46785 4 86 2.41E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS33920 f79a5f581b047814ea58f654d9214a76 624 Pfam PF00501 AMP-binding enzyme 69 500 4.8E-90 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS33920 f79a5f581b047814ea58f654d9214a76 624 SUPERFAMILY SSF56801 4 622 1.57E-161 T 28-03-2018 CU254_RS33920 f79a5f581b047814ea58f654d9214a76 624 Gene3D G3DSA:2.30.38.10 404 493 9.1E-17 T 28-03-2018 CU254_RS33920 f79a5f581b047814ea58f654d9214a76 624 Gene3D G3DSA:3.40.50.980 241 403 1.5E-38 T 28-03-2018 CU254_RS33920 f79a5f581b047814ea58f654d9214a76 624 Pfam PF13193 AMP-binding enzyme C-terminal domain 510 588 6.5E-26 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS33920 f79a5f581b047814ea58f654d9214a76 624 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 4 58 2.3E-20 T 28-03-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 CU254_RS33920 f79a5f581b047814ea58f654d9214a76 624 Gene3D G3DSA:3.40.50.980 50 240 1.2E-45 T 28-03-2018 CU254_RS33920 f79a5f581b047814ea58f654d9214a76 624 ProSitePatterns PS00455 Putative AMP-binding domain signature. 236 247 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS33920 f79a5f581b047814ea58f654d9214a76 624 Gene3D G3DSA:3.30.300.30 494 605 1.5E-24 T 28-03-2018 CU254_RS10745 139b085396a49da4d077419b8273bf9f 257 SUPERFAMILY SSF52540 3 232 4.69E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS10745 139b085396a49da4d077419b8273bf9f 257 SMART SM00382 30 220 5.2E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS10745 139b085396a49da4d077419b8273bf9f 257 Pfam PF00005 ABC transporter 21 172 6.7E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS10745 139b085396a49da4d077419b8273bf9f 257 Gene3D G3DSA:3.40.50.300 2 239 3.2E-57 T 28-03-2018 CU254_RS29650 2c855a85a2bc397ede3c69ed4b00e1f2 265 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 134 162 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS29650 2c855a85a2bc397ede3c69ed4b00e1f2 265 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 186 5.7E-4 T 28-03-2018 CU254_RS29650 2c855a85a2bc397ede3c69ed4b00e1f2 265 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 251 1.3E-63 T 28-03-2018 CU254_RS29650 2c855a85a2bc397ede3c69ed4b00e1f2 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 2.7E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS29650 2c855a85a2bc397ede3c69ed4b00e1f2 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 2.7E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS29650 2c855a85a2bc397ede3c69ed4b00e1f2 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 2.7E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS29650 2c855a85a2bc397ede3c69ed4b00e1f2 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 2.7E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS29650 2c855a85a2bc397ede3c69ed4b00e1f2 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 2.7E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS29650 2c855a85a2bc397ede3c69ed4b00e1f2 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 2.7E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS29650 2c855a85a2bc397ede3c69ed4b00e1f2 265 Gene3D G3DSA:3.40.50.720 46 261 6.4E-62 T 28-03-2018 CU254_RS29650 2c855a85a2bc397ede3c69ed4b00e1f2 265 Gene3D G3DSA:3.40.50.720 1 45 1.4E-8 T 28-03-2018 CU254_RS29650 2c855a85a2bc397ede3c69ed4b00e1f2 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 9.6E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS29650 2c855a85a2bc397ede3c69ed4b00e1f2 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 166 9.6E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS29650 2c855a85a2bc397ede3c69ed4b00e1f2 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 127 135 9.6E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS29650 2c855a85a2bc397ede3c69ed4b00e1f2 265 SUPERFAMILY SSF51735 5 253 1.02E-76 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS05290 f568e09f4f8d4fd6dfa0a4d86f2f2187 497 Gene3D G3DSA:3.40.50.1820 257 460 3.6E-4 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS05290 f568e09f4f8d4fd6dfa0a4d86f2f2187 497 Pfam PF06259 Alpha/beta hydrolase 259 407 5.4E-28 T 28-03-2018 IPR010427 Protein of unknown function DUF1023 CU254_RS15765 3c0424ee582def665ee749283e7e90fc 155 SMART SM00347 30 130 2.1E-20 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS15765 3c0424ee582def665ee749283e7e90fc 155 Gene3D G3DSA:1.10.10.10 13 142 1.3E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS15765 3c0424ee582def665ee749283e7e90fc 155 Pfam PF01047 MarR family 39 94 1.0E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS15765 3c0424ee582def665ee749283e7e90fc 155 SUPERFAMILY SSF46785 12 141 1.11E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS15765 3c0424ee582def665ee749283e7e90fc 155 PRINTS PR00598 Bacterial regulatory protein MarR family signature 71 86 2.9E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS15765 3c0424ee582def665ee749283e7e90fc 155 PRINTS PR00598 Bacterial regulatory protein MarR family signature 90 106 2.9E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS15765 3c0424ee582def665ee749283e7e90fc 155 PRINTS PR00598 Bacterial regulatory protein MarR family signature 54 70 2.9E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS15765 3c0424ee582def665ee749283e7e90fc 155 PRINTS PR00598 Bacterial regulatory protein MarR family signature 120 140 2.9E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS12470 11cc91c0f2a041c449935b4533d1f838 474 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 40 48 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CU254_RS12470 11cc91c0f2a041c449935b4533d1f838 474 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 367 461 2.6E-25 T 28-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal CU254_RS12470 11cc91c0f2a041c449935b4533d1f838 474 SMART SM01092 367 468 1.4E-26 T 28-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal CU254_RS12470 11cc91c0f2a041c449935b4533d1f838 474 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 196 360 1.4E-49 T 28-03-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 CU254_RS12470 11cc91c0f2a041c449935b4533d1f838 474 PIRSF PIRSF036557 1 474 1.2E-175 T 28-03-2018 IPR012175 Xanthine dehydrogenase, small subunit, bacteria CU254_RS12470 11cc91c0f2a041c449935b4533d1f838 474 SUPERFAMILY SSF54292 3 88 2.36E-14 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CU254_RS12470 11cc91c0f2a041c449935b4533d1f838 474 Pfam PF01799 [2Fe-2S] binding domain 83 162 1.3E-27 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CU254_RS12470 11cc91c0f2a041c449935b4533d1f838 474 Gene3D G3DSA:1.10.150.120 84 193 1.1E-34 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CU254_RS12470 11cc91c0f2a041c449935b4533d1f838 474 Gene3D G3DSA:3.30.43.10 194 246 9.0E-16 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CU254_RS12470 11cc91c0f2a041c449935b4533d1f838 474 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 6 72 2.3E-4 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CU254_RS12470 11cc91c0f2a041c449935b4533d1f838 474 SUPERFAMILY SSF55447 366 468 4.58E-30 T 28-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal CU254_RS12470 11cc91c0f2a041c449935b4533d1f838 474 SUPERFAMILY SSF47741 94 181 3.27E-26 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CU254_RS12470 11cc91c0f2a041c449935b4533d1f838 474 Gene3D G3DSA:3.30.465.10 247 361 5.6E-33 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CU254_RS12470 11cc91c0f2a041c449935b4533d1f838 474 Gene3D G3DSA:3.10.20.30 3 83 3.9E-21 T 28-03-2018 IPR012675 Beta-grasp domain CU254_RS12470 11cc91c0f2a041c449935b4533d1f838 474 Gene3D G3DSA:3.30.390.50 363 471 6.8E-28 T 28-03-2018 CU254_RS12470 11cc91c0f2a041c449935b4533d1f838 474 SUPERFAMILY SSF56176 188 360 1.31E-54 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CU254_RS33580 7fe05123dbb3ce975eb05ace44568a2c 121 Pfam PF04977 Septum formation initiator 11 85 6.6E-16 T 28-03-2018 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 CU254_RS26240 489121a451f0f3d4e40c9b915bf45eb4 408 Gene3D G3DSA:3.90.220.20 199 355 1.6E-19 T 28-03-2018 CU254_RS26240 489121a451f0f3d4e40c9b915bf45eb4 408 Gene3D G3DSA:3.90.220.20 1 178 4.4E-27 T 28-03-2018 CU254_RS26240 489121a451f0f3d4e40c9b915bf45eb4 408 SUPERFAMILY SSF116734 3 192 1.11E-29 T 28-03-2018 CU254_RS26240 489121a451f0f3d4e40c9b915bf45eb4 408 SUPERFAMILY SSF116734 202 400 1.57E-25 T 28-03-2018 CU254_RS26240 489121a451f0f3d4e40c9b915bf45eb4 408 Pfam PF01420 Type I restriction modification DNA specificity domain 227 361 1.2E-4 T 28-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 CU254_RS26240 489121a451f0f3d4e40c9b915bf45eb4 408 Pfam PF01420 Type I restriction modification DNA specificity domain 1 177 1.3E-11 T 28-03-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 CU254_RS40815 65b21f89eb0a3e379277b9831900a434 181 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 8.1E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS40815 65b21f89eb0a3e379277b9831900a434 181 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 8.1E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS40815 65b21f89eb0a3e379277b9831900a434 181 Gene3D G3DSA:1.10.10.60 11 62 1.6E-18 T 28-03-2018 CU254_RS40815 65b21f89eb0a3e379277b9831900a434 181 SUPERFAMILY SSF46689 6 83 7.98E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS40815 65b21f89eb0a3e379277b9831900a434 181 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 62 1.0E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS40815 65b21f89eb0a3e379277b9831900a434 181 Gene3D G3DSA:1.10.357.10 63 181 6.3E-14 T 28-03-2018 CU254_RS40815 65b21f89eb0a3e379277b9831900a434 181 SUPERFAMILY SSF48498 82 179 2.86E-11 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS38370 7b7e8becf5ead8613464c5e2186f99a0 863 Gene3D G3DSA:3.30.470.20 181 311 3.0E-43 T 28-03-2018 CU254_RS38370 7b7e8becf5ead8613464c5e2186f99a0 863 Gene3D G3DSA:3.50.30.10 759 863 1.2E-29 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CU254_RS38370 7b7e8becf5ead8613464c5e2186f99a0 863 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 17 311 1.9E-88 T 28-03-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 CU254_RS38370 7b7e8becf5ead8613464c5e2186f99a0 863 SUPERFAMILY SSF52009 755 857 4.84E-27 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CU254_RS38370 7b7e8becf5ead8613464c5e2186f99a0 863 Gene3D G3DSA:3.30.1490.20 1 180 7.4E-57 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CU254_RS38370 7b7e8becf5ead8613464c5e2186f99a0 863 SUPERFAMILY SSF56059 2 338 8.0E-96 T 28-03-2018 CU254_RS38370 7b7e8becf5ead8613464c5e2186f99a0 863 Pfam PF00391 PEP-utilising enzyme, mobile domain 784 855 6.3E-22 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CU254_RS08885 529c709c7a1be40e2f905f47a3d489f7 141 Gene3D G3DSA:3.30.70.970 40 132 2.6E-10 T 28-03-2018 IPR009671 Regulator of ribonuclease activity B domain CU254_RS08885 529c709c7a1be40e2f905f47a3d489f7 141 SUPERFAMILY SSF89946 48 133 4.84E-5 T 28-03-2018 IPR009671 Regulator of ribonuclease activity B domain CU254_RS07345 efcd5a6fc877fe14fab8fc2faeb386c0 286 SUPERFAMILY SSF57716 232 281 9.7E-15 T 28-03-2018 CU254_RS07345 efcd5a6fc877fe14fab8fc2faeb386c0 286 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 119 3.9E-35 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CU254_RS07345 efcd5a6fc877fe14fab8fc2faeb386c0 286 SUPERFAMILY SSF81624 2 149 1.57E-35 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CU254_RS07345 efcd5a6fc877fe14fab8fc2faeb386c0 286 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 281 40.304 T 28-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 CU254_RS07345 efcd5a6fc877fe14fab8fc2faeb386c0 286 SUPERFAMILY SSF46946 140 229 2.65E-24 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CU254_RS07345 efcd5a6fc877fe14fab8fc2faeb386c0 286 SMART SM00898 2 121 2.4E-48 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CU254_RS07345 efcd5a6fc877fe14fab8fc2faeb386c0 286 Gene3D G3DSA:1.10.8.50 142 286 5.2E-45 T 28-03-2018 CU254_RS07345 efcd5a6fc877fe14fab8fc2faeb386c0 286 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 140 227 2.0E-21 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CU254_RS07345 efcd5a6fc877fe14fab8fc2faeb386c0 286 SMART SM01232 140 232 6.8E-37 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CU254_RS07345 efcd5a6fc877fe14fab8fc2faeb386c0 286 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 280 1.8E-87 T 28-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 CU254_RS07345 efcd5a6fc877fe14fab8fc2faeb386c0 286 Pfam PF06827 Zinc finger found in FPG and IleRS 253 281 4.8E-8 T 28-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 CU254_RS07345 efcd5a6fc877fe14fab8fc2faeb386c0 286 Gene3D G3DSA:3.20.190.10 2 131 3.7E-45 T 28-03-2018 CU254_RS16505 a5e42e69a4d588c4b8d2021d211efa79 123 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 16 117 1.9E-18 T 28-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 CU254_RS16505 a5e42e69a4d588c4b8d2021d211efa79 123 Gene3D G3DSA:3.30.750.24 11 123 5.7E-15 T 28-03-2018 IPR002645 STAS domain CU254_RS16505 a5e42e69a4d588c4b8d2021d211efa79 123 SUPERFAMILY SSF52091 17 121 6.08E-18 T 28-03-2018 IPR002645 STAS domain CU254_RS16505 a5e42e69a4d588c4b8d2021d211efa79 123 Pfam PF13466 STAS domain 28 106 1.3E-9 T 28-03-2018 IPR002645 STAS domain CU254_RS10190 8870ec7549d8f220a91d7a0c6092cf3e 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 1.6E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS10190 8870ec7549d8f220a91d7a0c6092cf3e 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 1.6E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS10190 8870ec7549d8f220a91d7a0c6092cf3e 202 Gene3D G3DSA:1.10.10.60 7 68 1.0E-20 T 28-03-2018 CU254_RS10190 8870ec7549d8f220a91d7a0c6092cf3e 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 68 9.8E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS10190 8870ec7549d8f220a91d7a0c6092cf3e 202 SUPERFAMILY SSF46689 9 88 1.55E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS10190 8870ec7549d8f220a91d7a0c6092cf3e 202 Gene3D G3DSA:1.10.357.10 69 194 1.2E-10 T 28-03-2018 CU254_RS15890 4afd6647215ed389786a831d08c02fc4 333 Gene3D G3DSA:3.40.50.2000 164 328 6.0E-40 T 28-03-2018 CU254_RS15890 4afd6647215ed389786a831d08c02fc4 333 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 126 301 3.6E-17 T 28-03-2018 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 CU254_RS15890 4afd6647215ed389786a831d08c02fc4 333 SUPERFAMILY SSF53756 2 324 4.71E-61 T 28-03-2018 CU254_RS15890 4afd6647215ed389786a831d08c02fc4 333 Gene3D G3DSA:3.40.50.2000 1 159 2.6E-20 T 28-03-2018 CU254_RS24590 f4424efcf97dad88a6142815fa09b211 478 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 40 393 3.1E-104 T 28-03-2018 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 CU254_RS24590 f4424efcf97dad88a6142815fa09b211 478 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 352 376 - T 28-03-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 CU254_RS24590 f4424efcf97dad88a6142815fa09b211 478 Pfam PF01098 Cell cycle protein 40 394 9.8E-102 T 28-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 CU254_RS36720 0522026da80f8580dca15f602921169d 484 SUPERFAMILY SSF103473 266 473 1.44E-27 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS36720 0522026da80f8580dca15f602921169d 484 SUPERFAMILY SSF103473 14 211 1.44E-27 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS36720 0522026da80f8580dca15f602921169d 484 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 153 165 - T 28-03-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 CU254_RS36720 0522026da80f8580dca15f602921169d 484 Pfam PF00854 POT family 91 447 1.1E-59 T 28-03-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-427975 CU254_RS36720 0522026da80f8580dca15f602921169d 484 Gene3D G3DSA:1.20.1250.20 11 211 5.3E-21 T 28-03-2018 CU254_RS36720 0522026da80f8580dca15f602921169d 484 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 12 480 6.0E-146 T 28-03-2018 IPR005279 Dipeptide/tripeptide permease GO:0015197|GO:0015833|GO:0016020 CU254_RS36720 0522026da80f8580dca15f602921169d 484 Gene3D G3DSA:1.20.1250.20 272 478 4.2E-14 T 28-03-2018 CU254_RS21850 1cd1c4da11705cfb04d297b45c751398 285 Pfam PF13560 Helix-turn-helix domain 5 86 3.8E-18 T 28-03-2018 CU254_RS21850 1cd1c4da11705cfb04d297b45c751398 285 SUPERFAMILY SSF47413 32 79 3.26E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS21850 1cd1c4da11705cfb04d297b45c751398 285 Gene3D G3DSA:1.10.260.40 1 86 3.4E-16 T 28-03-2018 CU254_RS21850 1cd1c4da11705cfb04d297b45c751398 285 SMART SM00530 9 83 9.4E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS03825 ee2d4a08fa4c90e231bd06d4384ca51a 396 Gene3D G3DSA:2.40.110.10 125 229 5.2E-30 T 28-03-2018 CU254_RS03825 ee2d4a08fa4c90e231bd06d4384ca51a 396 Gene3D G3DSA:1.20.140.10 230 396 5.9E-50 T 28-03-2018 CU254_RS03825 ee2d4a08fa4c90e231bd06d4384ca51a 396 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 126 228 1.6E-21 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CU254_RS03825 ee2d4a08fa4c90e231bd06d4384ca51a 396 SUPERFAMILY SSF56645 9 251 5.37E-73 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS03825 ee2d4a08fa4c90e231bd06d4384ca51a 396 SUPERFAMILY SSF47203 241 394 2.26E-53 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS03825 ee2d4a08fa4c90e231bd06d4384ca51a 396 PIRSF PIRSF016578 4 126 1.4E-7 T 28-03-2018 CU254_RS03825 ee2d4a08fa4c90e231bd06d4384ca51a 396 PIRSF PIRSF016578 224 373 6.3E-9 T 28-03-2018 CU254_RS03825 ee2d4a08fa4c90e231bd06d4384ca51a 396 Gene3D G3DSA:1.10.540.10 6 124 4.3E-36 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS03825 ee2d4a08fa4c90e231bd06d4384ca51a 396 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 242 390 7.5E-47 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS03825 ee2d4a08fa4c90e231bd06d4384ca51a 396 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 11 122 4.8E-35 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS29210 b5d948eed0fe53cfb05099f978ef7bd5 386 SUPERFAMILY SSF50331 244 362 6.8E-12 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CU254_RS29210 b5d948eed0fe53cfb05099f978ef7bd5 386 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS29210 b5d948eed0fe53cfb05099f978ef7bd5 386 Gene3D G3DSA:3.40.50.300 1 237 5.5E-71 T 28-03-2018 CU254_RS29210 b5d948eed0fe53cfb05099f978ef7bd5 386 Pfam PF00005 ABC transporter 19 167 3.0E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS29210 b5d948eed0fe53cfb05099f978ef7bd5 386 SUPERFAMILY SSF52540 4 248 5.46E-81 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS29210 b5d948eed0fe53cfb05099f978ef7bd5 386 Gene3D G3DSA:2.40.50.140 238 355 7.2E-5 T 28-03-2018 CU254_RS29210 b5d948eed0fe53cfb05099f978ef7bd5 386 Pfam PF08402 TOBE domain 286 361 1.1E-6 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CU254_RS29210 b5d948eed0fe53cfb05099f978ef7bd5 386 SMART SM00382 28 217 2.0E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS15985 527427167d0f6396fba9cea40b08b1a6 323 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 296 311 1.3E-5 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS15985 527427167d0f6396fba9cea40b08b1a6 323 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 281 296 1.3E-5 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS15985 527427167d0f6396fba9cea40b08b1a6 323 SMART SM00418 252 321 5.0E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS15985 527427167d0f6396fba9cea40b08b1a6 323 Pfam PF01022 Bacterial regulatory protein, arsR family 261 298 1.2E-10 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS15985 527427167d0f6396fba9cea40b08b1a6 323 Gene3D G3DSA:1.10.10.10 110 323 3.4E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS15985 527427167d0f6396fba9cea40b08b1a6 323 SUPERFAMILY SSF46785 260 319 1.7E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS00430 7dad4908ab58fe81aa9823797ecdba10 661 Gene3D G3DSA:3.40.390.10 115 454 1.5E-5 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CU254_RS00430 7dad4908ab58fe81aa9823797ecdba10 661 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 208 501 1.4E-60 T 28-03-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 CU254_RS00430 7dad4908ab58fe81aa9823797ecdba10 661 SUPERFAMILY SSF55486 263 317 2.39E-12 T 28-03-2018 CU254_RS00430 7dad4908ab58fe81aa9823797ecdba10 661 SUPERFAMILY SSF55486 364 442 2.39E-12 T 28-03-2018 CU254_RS00430 7dad4908ab58fe81aa9823797ecdba10 661 Pfam PF05547 Immune inhibitor A peptidase M6 164 463 1.1E-58 T 28-03-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 CU254_RS00430 7dad4908ab58fe81aa9823797ecdba10 661 Pfam PF05547 Immune inhibitor A peptidase M6 483 650 1.4E-24 T 28-03-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 CU254_RS33030 5a00edab2ebe43c81fed52941d2f663a 510 Pfam PF07690 Major Facilitator Superfamily 28 419 1.3E-61 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS33030 5a00edab2ebe43c81fed52941d2f663a 510 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 23 428 5.6E-135 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CU254_RS33030 5a00edab2ebe43c81fed52941d2f663a 510 Gene3D G3DSA:1.20.1250.20 269 505 3.6E-34 T 28-03-2018 CU254_RS33030 5a00edab2ebe43c81fed52941d2f663a 510 SUPERFAMILY SSF103473 258 430 1.19E-72 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS33030 5a00edab2ebe43c81fed52941d2f663a 510 SUPERFAMILY SSF103473 18 204 1.19E-72 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS33030 5a00edab2ebe43c81fed52941d2f663a 510 SUPERFAMILY SSF103473 466 492 1.19E-72 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS33030 5a00edab2ebe43c81fed52941d2f663a 510 Gene3D G3DSA:1.20.1250.20 17 207 2.3E-31 T 28-03-2018 CU254_RS33780 d3df096bd6368ec20f6a357ee9381bc7 281 SUPERFAMILY SSF53474 36 258 7.24E-22 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS33780 d3df096bd6368ec20f6a357ee9381bc7 281 Gene3D G3DSA:3.40.50.1820 8 275 3.0E-24 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS33780 d3df096bd6368ec20f6a357ee9381bc7 281 Pfam PF01674 Lipase (class 2) 42 124 6.1E-7 T 28-03-2018 IPR002918 Lipase EstA/Esterase EstB GO:0016787 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 CU254_RS33015 832b49a94b9205b09795b025cc8d1b3e 456 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 10 296 4.5E-66 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CU254_RS33015 832b49a94b9205b09795b025cc8d1b3e 456 Gene3D G3DSA:3.10.580.10 319 456 2.1E-20 T 28-03-2018 CU254_RS33015 832b49a94b9205b09795b025cc8d1b3e 456 SMART SM00116 409 454 0.28 T 28-03-2018 IPR000644 CBS domain CU254_RS33015 832b49a94b9205b09795b025cc8d1b3e 456 SMART SM00116 339 392 0.012 T 28-03-2018 IPR000644 CBS domain CU254_RS33015 832b49a94b9205b09795b025cc8d1b3e 456 TIGRFAM TIGR01137 cysta_beta: cystathionine beta-synthase 4 454 8.5E-199 T 28-03-2018 IPR005857 Cystathionine beta-synthase GO:0004122|GO:0005737|GO:0019343 KEGG: 00260+4.2.1.22|KEGG: 00270+4.2.1.22|MetaCyc: PWY-801 CU254_RS33015 832b49a94b9205b09795b025cc8d1b3e 456 Gene3D G3DSA:3.40.50.1100 41 141 2.8E-37 T 28-03-2018 CU254_RS33015 832b49a94b9205b09795b025cc8d1b3e 456 Pfam PF00571 CBS domain 406 454 1.2E-5 T 28-03-2018 IPR000644 CBS domain CU254_RS33015 832b49a94b9205b09795b025cc8d1b3e 456 Pfam PF00571 CBS domain 339 391 6.2E-5 T 28-03-2018 IPR000644 CBS domain CU254_RS33015 832b49a94b9205b09795b025cc8d1b3e 456 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 28-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 CU254_RS33015 832b49a94b9205b09795b025cc8d1b3e 456 SUPERFAMILY SSF53686 2 317 5.76E-95 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CU254_RS33015 832b49a94b9205b09795b025cc8d1b3e 456 Gene3D G3DSA:3.40.50.1100 142 316 1.4E-50 T 28-03-2018 CU254_RS33015 832b49a94b9205b09795b025cc8d1b3e 456 SUPERFAMILY SSF54631 325 455 2.65E-16 T 28-03-2018 CU254_RS34380 79eb110c4780cfaf2a4ebfc268034043 215 Gene3D G3DSA:1.10.357.10 64 214 8.9E-33 T 28-03-2018 CU254_RS34380 79eb110c4780cfaf2a4ebfc268034043 215 SUPERFAMILY SSF48498 94 210 3.89E-25 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS34380 79eb110c4780cfaf2a4ebfc268034043 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 66 1.5E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS34380 79eb110c4780cfaf2a4ebfc268034043 215 Pfam PF13305 WHG domain 98 190 4.7E-9 T 28-03-2018 IPR025996 WHG domain CU254_RS34380 79eb110c4780cfaf2a4ebfc268034043 215 Gene3D G3DSA:1.10.10.60 3 63 3.6E-16 T 28-03-2018 CU254_RS34380 79eb110c4780cfaf2a4ebfc268034043 215 SUPERFAMILY SSF46689 10 85 1.2E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS22900 15c226d706200cae21e85ee9bf250e70 337 Pfam PF02653 Branched-chain amino acid transport system / permease component 34 320 1.3E-44 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CU254_RS22900 15c226d706200cae21e85ee9bf250e70 337 Gene3D G3DSA:1.10.3470.10 5 325 5.0E-49 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CU254_RS01050 83c0985d6f5ade908a94163c399c5c12 229 Gene3D G3DSA:3.40.50.2300 1 124 1.1E-35 T 28-03-2018 CU254_RS01050 83c0985d6f5ade908a94163c399c5c12 229 SUPERFAMILY SSF46894 131 228 8.22E-32 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS01050 83c0985d6f5ade908a94163c399c5c12 229 SMART SM00448 2 112 4.4E-44 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS01050 83c0985d6f5ade908a94163c399c5c12 229 Gene3D G3DSA:1.10.10.10 125 229 2.1E-33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS01050 83c0985d6f5ade908a94163c399c5c12 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 227 5.1E-27 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS01050 83c0985d6f5ade908a94163c399c5c12 229 SUPERFAMILY SSF52172 3 119 2.56E-40 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS01050 83c0985d6f5ade908a94163c399c5c12 229 Pfam PF00072 Response regulator receiver domain 4 113 4.5E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS01050 83c0985d6f5ade908a94163c399c5c12 229 SMART SM00862 151 227 4.1E-29 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS35850 8062f64d6e848706078ba6555ff7ee1b 485 Gene3D G3DSA:1.10.287.130 261 318 0.002 T 28-03-2018 CU254_RS35850 8062f64d6e848706078ba6555ff7ee1b 485 SMART SM00091 13 83 0.034 T 28-03-2018 IPR000014 PAS domain CU254_RS35850 8062f64d6e848706078ba6555ff7ee1b 485 SMART SM00091 140 207 0.087 T 28-03-2018 IPR000014 PAS domain CU254_RS35850 8062f64d6e848706078ba6555ff7ee1b 485 SUPERFAMILY SSF55785 18 125 9.07E-13 T 28-03-2018 IPR000014 PAS domain CU254_RS35850 8062f64d6e848706078ba6555ff7ee1b 485 SUPERFAMILY SSF47384 259 329 4.12E-6 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS35850 8062f64d6e848706078ba6555ff7ee1b 485 Gene3D G3DSA:3.30.450.20 5 133 8.9E-14 T 28-03-2018 CU254_RS35850 8062f64d6e848706078ba6555ff7ee1b 485 Gene3D G3DSA:3.30.565.10 319 482 2.6E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS35850 8062f64d6e848706078ba6555ff7ee1b 485 Gene3D G3DSA:3.30.450.20 134 260 7.7E-12 T 28-03-2018 CU254_RS35850 8062f64d6e848706078ba6555ff7ee1b 485 PRINTS PR00344 Bacterial sensor protein C-terminal signature 418 432 3.8E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS35850 8062f64d6e848706078ba6555ff7ee1b 485 PRINTS PR00344 Bacterial sensor protein C-terminal signature 467 480 3.8E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS35850 8062f64d6e848706078ba6555ff7ee1b 485 PRINTS PR00344 Bacterial sensor protein C-terminal signature 443 461 3.8E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS35850 8062f64d6e848706078ba6555ff7ee1b 485 SUPERFAMILY SSF55874 321 481 7.99E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS35850 8062f64d6e848706078ba6555ff7ee1b 485 SMART SM00387 377 483 1.1E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS35850 8062f64d6e848706078ba6555ff7ee1b 485 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 16 135 3.1E-7 T 28-03-2018 IPR000014 PAS domain CU254_RS35850 8062f64d6e848706078ba6555ff7ee1b 485 SUPERFAMILY SSF55785 126 245 4.71E-8 T 28-03-2018 IPR000014 PAS domain CU254_RS35850 8062f64d6e848706078ba6555ff7ee1b 485 Pfam PF13188 PAS domain 17 53 3.0E-4 T 28-03-2018 IPR000014 PAS domain CU254_RS35850 8062f64d6e848706078ba6555ff7ee1b 485 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 384 481 4.4E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS32880 52eeb7780abef680cd817b67ea9af93f 252 Gene3D G3DSA:3.40.1180.10 7 252 5.8E-82 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CU254_RS32880 52eeb7780abef680cd817b67ea9af93f 252 SUPERFAMILY SSF64005 19 246 2.75E-72 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CU254_RS32880 52eeb7780abef680cd817b67ea9af93f 252 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 22 251 2.3E-63 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CU254_RS32880 52eeb7780abef680cd817b67ea9af93f 252 Pfam PF01255 Putative undecaprenyl diphosphate synthase 29 251 2.8E-71 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CU254_RS32880 52eeb7780abef680cd817b67ea9af93f 252 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 21 252 35.193 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CU254_RS32880 52eeb7780abef680cd817b67ea9af93f 252 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 197 214 - T 28-03-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199 CU254_RS37375 843053fec68e6630200e7ea496fb8d30 329 SUPERFAMILY SSF46689 268 319 4.48E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS37375 843053fec68e6630200e7ea496fb8d30 329 Gene3D G3DSA:1.10.10.60 209 271 3.1E-10 T 28-03-2018 CU254_RS37375 843053fec68e6630200e7ea496fb8d30 329 SMART SM00342 232 315 1.8E-29 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS37375 843053fec68e6630200e7ea496fb8d30 329 SUPERFAMILY SSF46689 215 265 1.52E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS37375 843053fec68e6630200e7ea496fb8d30 329 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 269 311 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CU254_RS37375 843053fec68e6630200e7ea496fb8d30 329 Gene3D G3DSA:2.60.120.280 37 199 2.1E-9 T 28-03-2018 CU254_RS37375 843053fec68e6630200e7ea496fb8d30 329 Gene3D G3DSA:1.10.10.60 272 322 3.2E-14 T 28-03-2018 CU254_RS37375 843053fec68e6630200e7ea496fb8d30 329 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 299 315 2.2E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CU254_RS37375 843053fec68e6630200e7ea496fb8d30 329 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 284 299 2.2E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CU254_RS37375 843053fec68e6630200e7ea496fb8d30 329 Pfam PF12833 Helix-turn-helix domain 238 316 2.2E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS37375 843053fec68e6630200e7ea496fb8d30 329 Pfam PF12852 Cupin 15 199 2.5E-39 T 28-03-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain CU254_RS05765 f69e363e96106bafddfe01bbef451f25 384 Pfam PF07730 Histidine kinase 195 262 1.4E-16 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CU254_RS05765 f69e363e96106bafddfe01bbef451f25 384 SUPERFAMILY SSF55874 269 384 6.86E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS05765 f69e363e96106bafddfe01bbef451f25 384 Gene3D G3DSA:3.30.565.10 252 384 6.7E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS14075 dd86757d83baae05661cce2a1609c562 152 SMART SM00347 25 125 9.3E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS14075 dd86757d83baae05661cce2a1609c562 152 Pfam PF01047 MarR family 32 90 2.1E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS14075 dd86757d83baae05661cce2a1609c562 152 SUPERFAMILY SSF46785 8 136 4.92E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS14075 dd86757d83baae05661cce2a1609c562 152 Gene3D G3DSA:1.10.10.10 2 149 1.1E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS12870 5d0473441ec8cce0f27347d2492fe7b0 522 Pfam PF13193 AMP-binding enzyme C-terminal domain 430 505 6.6E-20 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS12870 5d0473441ec8cce0f27347d2492fe7b0 522 Pfam PF00501 AMP-binding enzyme 18 421 1.5E-88 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS12870 5d0473441ec8cce0f27347d2492fe7b0 522 Gene3D G3DSA:3.40.50.980 5 179 2.7E-37 T 28-03-2018 CU254_RS12870 5d0473441ec8cce0f27347d2492fe7b0 522 Gene3D G3DSA:3.30.300.30 417 521 1.6E-29 T 28-03-2018 CU254_RS12870 5d0473441ec8cce0f27347d2492fe7b0 522 SUPERFAMILY SSF56801 7 514 3.27E-138 T 28-03-2018 CU254_RS12870 5d0473441ec8cce0f27347d2492fe7b0 522 Gene3D G3DSA:2.30.38.10 329 414 1.8E-21 T 28-03-2018 CU254_RS12870 5d0473441ec8cce0f27347d2492fe7b0 522 Gene3D G3DSA:3.40.50.980 180 328 1.0E-38 T 28-03-2018 CU254_RS17815 34da008b1edcc7c2bfe8ec8dbe5a9f9a 385 SUPERFAMILY SSF55424 308 381 2.2E-15 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CU254_RS17815 34da008b1edcc7c2bfe8ec8dbe5a9f9a 385 Gene3D G3DSA:3.50.50.60 122 234 7.6E-25 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS17815 34da008b1edcc7c2bfe8ec8dbe5a9f9a 385 Gene3D G3DSA:3.50.50.60 239 312 4.8E-4 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS17815 34da008b1edcc7c2bfe8ec8dbe5a9f9a 385 Gene3D G3DSA:3.30.390.30 314 384 7.9E-18 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CU254_RS17815 34da008b1edcc7c2bfe8ec8dbe5a9f9a 385 Gene3D G3DSA:3.50.50.60 1 121 1.1E-17 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS17815 34da008b1edcc7c2bfe8ec8dbe5a9f9a 385 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 293 3.0E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS17815 34da008b1edcc7c2bfe8ec8dbe5a9f9a 385 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 1.1E-8 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CU254_RS17815 34da008b1edcc7c2bfe8ec8dbe5a9f9a 385 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 98 106 1.1E-8 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CU254_RS17815 34da008b1edcc7c2bfe8ec8dbe5a9f9a 385 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 137 161 1.1E-8 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CU254_RS17815 34da008b1edcc7c2bfe8ec8dbe5a9f9a 385 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 262 280 1.1E-8 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CU254_RS17815 34da008b1edcc7c2bfe8ec8dbe5a9f9a 385 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 229 250 1.1E-8 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CU254_RS17815 34da008b1edcc7c2bfe8ec8dbe5a9f9a 385 SUPERFAMILY SSF51905 140 302 4.86E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS17815 34da008b1edcc7c2bfe8ec8dbe5a9f9a 385 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 3.5E-21 T 28-03-2018 CU254_RS17815 34da008b1edcc7c2bfe8ec8dbe5a9f9a 385 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 252 274 3.5E-21 T 28-03-2018 CU254_RS17815 34da008b1edcc7c2bfe8ec8dbe5a9f9a 385 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 227 243 3.5E-21 T 28-03-2018 CU254_RS17815 34da008b1edcc7c2bfe8ec8dbe5a9f9a 385 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 141 159 3.5E-21 T 28-03-2018 CU254_RS17815 34da008b1edcc7c2bfe8ec8dbe5a9f9a 385 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 97 115 3.5E-21 T 28-03-2018 CU254_RS17815 34da008b1edcc7c2bfe8ec8dbe5a9f9a 385 Pfam PF14759 Reductase C-terminal 314 375 9.4E-12 T 28-03-2018 IPR028202 Reductase, C-terminal CU254_RS17815 34da008b1edcc7c2bfe8ec8dbe5a9f9a 385 SUPERFAMILY SSF51905 3 185 5.62E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS42345 8580679587379bffbe488b05da523b7b 304 SUPERFAMILY SSF52096 34 301 9.44E-74 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS42345 8580679587379bffbe488b05da523b7b 304 TIGRFAM TIGR01929 menB: naphthoate synthase 20 299 1.1E-126 T 28-03-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 CU254_RS42345 8580679587379bffbe488b05da523b7b 304 Pfam PF00378 Enoyl-CoA hydratase/isomerase 35 299 8.9E-52 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CU254_RS42345 8580679587379bffbe488b05da523b7b 304 Hamap MF_01934 1,4-dihydroxy-2-naphthoyl-CoA synthase [menB]. 12 303 52.728 T 28-03-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 CU254_RS42345 8580679587379bffbe488b05da523b7b 304 Gene3D G3DSA:3.90.226.10 4 243 9.4E-65 T 28-03-2018 CU254_RS42345 8580679587379bffbe488b05da523b7b 304 Gene3D G3DSA:1.10.12.10 244 292 8.6E-16 T 28-03-2018 IPR014748 Crontonase, C-terminal CU254_RS34255 dee5085b96c79471515e145cb50a6c9b 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 209 8.3E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS34255 dee5085b96c79471515e145cb50a6c9b 217 Gene3D G3DSA:1.10.10.10 135 214 5.2E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS34255 dee5085b96c79471515e145cb50a6c9b 217 ProSitePatterns PS00622 LuxR-type HTH domain signature. 169 196 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS34255 dee5085b96c79471515e145cb50a6c9b 217 SMART SM00421 152 209 3.7E-21 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS34255 dee5085b96c79471515e145cb50a6c9b 217 Gene3D G3DSA:3.40.50.2300 1 134 7.7E-31 T 28-03-2018 CU254_RS34255 dee5085b96c79471515e145cb50a6c9b 217 SUPERFAMILY SSF46894 140 216 4.08E-20 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS34255 dee5085b96c79471515e145cb50a6c9b 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 1.3E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS34255 dee5085b96c79471515e145cb50a6c9b 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 1.3E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS34255 dee5085b96c79471515e145cb50a6c9b 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 1.3E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS34255 dee5085b96c79471515e145cb50a6c9b 217 SMART SM00448 2 116 2.7E-20 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS34255 dee5085b96c79471515e145cb50a6c9b 217 SUPERFAMILY SSF52172 3 129 1.85E-26 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS34255 dee5085b96c79471515e145cb50a6c9b 217 Pfam PF00072 Response regulator receiver domain 6 116 6.6E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS12415 0f0d7f6692ec96f3cd346a9fd16034df 296 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 8 227 8.6E-54 T 28-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D CU254_RS12415 0f0d7f6692ec96f3cd346a9fd16034df 296 SUPERFAMILY SSF50891 96 252 9.48E-28 T 28-03-2018 IPR029000 Cyclophilin-like domain CU254_RS12415 0f0d7f6692ec96f3cd346a9fd16034df 296 Gene3D G3DSA:2.40.100.10 94 254 9.5E-41 T 28-03-2018 IPR029000 Cyclophilin-like domain CU254_RS12415 0f0d7f6692ec96f3cd346a9fd16034df 296 Gene3D G3DSA:3.30.1360.40 2 88 2.5E-20 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CU254_RS12415 0f0d7f6692ec96f3cd346a9fd16034df 296 SUPERFAMILY SSF160467 8 100 1.11E-19 T 28-03-2018 CU254_RS12415 0f0d7f6692ec96f3cd346a9fd16034df 296 SMART SM00796 7 230 5.5E-70 T 28-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D CU254_RS10285 a3927d00c7f5020fda2aa3e4efe67e91 234 Gene3D G3DSA:3.40.50.150 24 192 4.4E-28 T 28-03-2018 CU254_RS10285 a3927d00c7f5020fda2aa3e4efe67e91 234 Pfam PF13649 Methyltransferase domain 46 139 3.4E-20 T 28-03-2018 CU254_RS10285 a3927d00c7f5020fda2aa3e4efe67e91 234 SUPERFAMILY SSF53335 9 181 2.13E-36 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS13620 a4b80070c906a16fcd75ec2ff200ef81 187 SMART SM00471 34 148 5.1E-11 T 28-03-2018 IPR003607 HD/PDEase domain CU254_RS13620 a4b80070c906a16fcd75ec2ff200ef81 187 Gene3D G3DSA:1.10.3210.10 1 179 4.8E-38 T 28-03-2018 CU254_RS13620 a4b80070c906a16fcd75ec2ff200ef81 187 SUPERFAMILY SSF109604 11 150 6.28E-33 T 28-03-2018 CU254_RS13620 a4b80070c906a16fcd75ec2ff200ef81 187 Pfam PF13023 HD domain 17 147 2.4E-27 T 28-03-2018 IPR006674 HD domain CU254_RS05055 5eaf625aa8407aa59d22d05e96246a42 201 TIGRFAM TIGR04037 LLM_duo_CE1759: LLM-partnered FMN reductase, CE1759 family 6 198 2.8E-84 T 28-03-2018 IPR023932 Uncharacterised protein family, CE1759 CU254_RS05055 5eaf625aa8407aa59d22d05e96246a42 201 Gene3D G3DSA:3.40.50.360 1 183 4.8E-45 T 28-03-2018 IPR029039 Flavoprotein-like domain CU254_RS05055 5eaf625aa8407aa59d22d05e96246a42 201 SUPERFAMILY SSF52218 4 180 3.11E-32 T 28-03-2018 IPR029039 Flavoprotein-like domain CU254_RS05055 5eaf625aa8407aa59d22d05e96246a42 201 Pfam PF03358 NADPH-dependent FMN reductase 6 154 5.1E-38 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CU254_RS23105 f2d34f1790148082889d0611c5598798 226 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 183 9.3E-27 T 28-03-2018 IPR023214 HAD-like domain CU254_RS23105 f2d34f1790148082889d0611c5598798 226 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 79 183 3.3E-14 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CU254_RS23105 f2d34f1790148082889d0611c5598798 226 Gene3D G3DSA:1.10.150.240 17 75 8.3E-10 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CU254_RS23105 f2d34f1790148082889d0611c5598798 226 Gene3D G3DSA:3.40.50.1000 76 203 3.6E-26 T 28-03-2018 IPR023214 HAD-like domain CU254_RS23105 f2d34f1790148082889d0611c5598798 226 SUPERFAMILY SSF56784 5 188 7.59E-46 T 28-03-2018 IPR023214 HAD-like domain CU254_RS23105 f2d34f1790148082889d0611c5598798 226 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 128 144 6.7E-5 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CU254_RS23105 f2d34f1790148082889d0611c5598798 226 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 98 111 6.7E-5 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CU254_RS23105 f2d34f1790148082889d0611c5598798 226 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 146 166 6.7E-5 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CU254_RS23105 f2d34f1790148082889d0611c5598798 226 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 4 15 6.7E-5 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CU254_RS01820 53e1f59b522980b3c330fe107f7887ae 1167 Pfam PF04560 RNA polymerase Rpb2, domain 7 1052 1126 6.9E-27 T 28-03-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CU254_RS01820 53e1f59b522980b3c330fe107f7887ae 1167 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 32 1128 12.319 T 28-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CU254_RS01820 53e1f59b522980b3c330fe107f7887ae 1167 Pfam PF04563 RNA polymerase beta subunit 46 415 2.2E-22 T 28-03-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CU254_RS01820 53e1f59b522980b3c330fe107f7887ae 1167 Gene3D G3DSA:2.40.270.10 703 805 2.5E-10 T 28-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CU254_RS01820 53e1f59b522980b3c330fe107f7887ae 1167 Gene3D G3DSA:2.40.270.10 831 943 3.4E-48 T 28-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CU254_RS01820 53e1f59b522980b3c330fe107f7887ae 1167 Gene3D G3DSA:2.40.270.10 944 1028 1.7E-17 T 28-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CU254_RS01820 53e1f59b522980b3c330fe107f7887ae 1167 Pfam PF04561 RNA polymerase Rpb2, domain 2 174 370 9.2E-29 T 28-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CU254_RS01820 53e1f59b522980b3c330fe107f7887ae 1167 Pfam PF00562 RNA polymerase Rpb2, domain 6 634 1050 3.7E-159 T 28-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CU254_RS01820 53e1f59b522980b3c330fe107f7887ae 1167 ProSitePatterns PS01166 RNA polymerases beta chain signature. 873 885 - T 28-03-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CU254_RS01820 53e1f59b522980b3c330fe107f7887ae 1167 Pfam PF04565 RNA polymerase Rpb2, domain 3 429 497 1.5E-28 T 28-03-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CU254_RS01820 53e1f59b522980b3c330fe107f7887ae 1167 Gene3D G3DSA:3.90.1110.10 171 344 7.3E-69 T 28-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CU254_RS01820 53e1f59b522980b3c330fe107f7887ae 1167 Pfam PF10385 RNA polymerase beta subunit external 1 domain 507 573 3.0E-26 T 28-03-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CU254_RS01820 53e1f59b522980b3c330fe107f7887ae 1167 SUPERFAMILY SSF64484 31 1139 0.0 T 28-03-2018 CU254_RS01820 53e1f59b522980b3c330fe107f7887ae 1167 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 248 847 0.0 T 28-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CU254_RS01820 53e1f59b522980b3c330fe107f7887ae 1167 Gene3D G3DSA:3.90.1100.10 345 563 4.3E-80 T 28-03-2018 CU254_RS01820 53e1f59b522980b3c330fe107f7887ae 1167 Gene3D G3DSA:3.90.1100.10 565 630 4.5E-13 T 28-03-2018 CU254_RS01820 53e1f59b522980b3c330fe107f7887ae 1167 Gene3D G3DSA:3.90.1800.10 1053 1097 1.6E-10 T 28-03-2018 CU254_RS01820 53e1f59b522980b3c330fe107f7887ae 1167 Gene3D G3DSA:2.40.50.100 631 702 1.4E-25 T 28-03-2018 CU254_RS14050 ef1b830411bff69c7ebfa51b70077017 285 Hamap MF_00361 NAD kinase [nadK]. 2 276 26.586 T 28-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CU254_RS14050 ef1b830411bff69c7ebfa51b70077017 285 Gene3D G3DSA:3.40.50.10330 7 127 1.4E-20 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 CU254_RS14050 ef1b830411bff69c7ebfa51b70077017 285 Gene3D G3DSA:2.60.200.30 128 252 6.2E-28 T 28-03-2018 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CU254_RS14050 ef1b830411bff69c7ebfa51b70077017 285 Pfam PF01513 ATP-NAD kinase 55 261 2.5E-42 T 28-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CU254_RS14050 ef1b830411bff69c7ebfa51b70077017 285 SUPERFAMILY SSF111331 20 276 7.72E-61 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain CU254_RS01370 5eca67ca3e4d397a30ae462e8aafa087 834 Gene3D G3DSA:3.10.20.30 14 184 7.3E-14 T 28-03-2018 IPR012675 Beta-grasp domain CU254_RS01370 5eca67ca3e4d397a30ae462e8aafa087 834 SMART SM00929 107 147 7.0E-19 T 28-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS01370 5eca67ca3e4d397a30ae462e8aafa087 834 SUPERFAMILY SSF53706 244 698 2.36E-73 T 28-03-2018 CU254_RS01370 5eca67ca3e4d397a30ae462e8aafa087 834 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 20 97 8.6E-16 T 28-03-2018 CU254_RS01370 5eca67ca3e4d397a30ae462e8aafa087 834 ProSitePatterns PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 122 134 - T 28-03-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS01370 5eca67ca3e4d397a30ae462e8aafa087 834 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 256 306 1.9E-5 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS01370 5eca67ca3e4d397a30ae462e8aafa087 834 SMART SM00926 253 307 5.4E-5 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS01370 5eca67ca3e4d397a30ae462e8aafa087 834 SUPERFAMILY SSF54292 20 96 2.58E-17 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CU254_RS01370 5eca67ca3e4d397a30ae462e8aafa087 834 TIGRFAM TIGR01973 NuoG: NADH dehydrogenase (quinone), G subunit 22 667 7.8E-164 T 28-03-2018 IPR010228 NADH:ubiquinone oxidoreductase, subunit G GO:0016651|GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS01370 5eca67ca3e4d397a30ae462e8aafa087 834 Gene3D G3DSA:2.40.40.20 751 832 2.5E-13 T 28-03-2018 CU254_RS01370 5eca67ca3e4d397a30ae462e8aafa087 834 SUPERFAMILY SSF50692 738 811 2.71E-8 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain CU254_RS01370 5eca67ca3e4d397a30ae462e8aafa087 834 Gene3D G3DSA:3.40.50.740 311 476 1.6E-21 T 28-03-2018 CU254_RS01370 5eca67ca3e4d397a30ae462e8aafa087 834 Pfam PF00384 Molybdopterin oxidoreductase 562 657 2.2E-6 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS01370 5eca67ca3e4d397a30ae462e8aafa087 834 Pfam PF00384 Molybdopterin oxidoreductase 310 454 6.7E-13 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS01370 5eca67ca3e4d397a30ae462e8aafa087 834 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 108 146 1.2E-15 T 28-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS01370 5eca67ca3e4d397a30ae462e8aafa087 834 ProSitePatterns PS00643 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. 170 180 - T 28-03-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS01370 5eca67ca3e4d397a30ae462e8aafa087 834 Gene3D G3DSA:3.40.50.740 477 708 1.7E-30 T 28-03-2018 CU254_RS01370 5eca67ca3e4d397a30ae462e8aafa087 834 Gene3D G3DSA:2.20.25.90 253 308 1.2E-9 T 28-03-2018 CU254_RS01370 5eca67ca3e4d397a30ae462e8aafa087 834 SUPERFAMILY SSF54862 100 248 7.11E-30 T 28-03-2018 CU254_RS01370 5eca67ca3e4d397a30ae462e8aafa087 834 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 49 66 - T 28-03-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS09825 f4c8bab961cfd6eebd66539bdc9aea42 489 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 66 2.4E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS09825 f4c8bab961cfd6eebd66539bdc9aea42 489 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 50 2.4E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS09825 f4c8bab961cfd6eebd66539bdc9aea42 489 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 76 1.0E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS09825 f4c8bab961cfd6eebd66539bdc9aea42 489 Gene3D G3DSA:1.10.10.10 5 78 5.6E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS09825 f4c8bab961cfd6eebd66539bdc9aea42 489 SUPERFAMILY SSF53383 112 467 2.11E-88 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS09825 f4c8bab961cfd6eebd66539bdc9aea42 489 Pfam PF00155 Aminotransferase class I and II 131 395 1.5E-17 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CU254_RS09825 f4c8bab961cfd6eebd66539bdc9aea42 489 SMART SM00345 17 76 1.5E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS09825 f4c8bab961cfd6eebd66539bdc9aea42 489 SUPERFAMILY SSF46785 7 80 1.14E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS09825 f4c8bab961cfd6eebd66539bdc9aea42 489 Gene3D G3DSA:3.40.640.10 131 373 2.9E-46 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS09825 f4c8bab961cfd6eebd66539bdc9aea42 489 Gene3D G3DSA:3.90.1150.10 374 469 2.3E-14 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS00970 09bb8355c8237bf2c394d0428d0ed59b 290 Gene3D G3DSA:3.40.50.170 89 287 2.1E-51 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CU254_RS00970 09bb8355c8237bf2c394d0428d0ed59b 290 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 93 115 2.5E-57 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CU254_RS00970 09bb8355c8237bf2c394d0428d0ed59b 290 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 242 264 2.5E-57 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CU254_RS00970 09bb8355c8237bf2c394d0428d0ed59b 290 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 264 289 2.5E-57 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CU254_RS00970 09bb8355c8237bf2c394d0428d0ed59b 290 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 9 35 2.5E-57 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CU254_RS00970 09bb8355c8237bf2c394d0428d0ed59b 290 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 41 53 2.5E-57 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CU254_RS00970 09bb8355c8237bf2c394d0428d0ed59b 290 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 115 142 2.5E-57 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CU254_RS00970 09bb8355c8237bf2c394d0428d0ed59b 290 SUPERFAMILY SSF53328 93 288 2.49E-57 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CU254_RS00970 09bb8355c8237bf2c394d0428d0ed59b 290 Gene3D G3DSA:3.30.70.260 1 88 3.8E-25 T 28-03-2018 CU254_RS00970 09bb8355c8237bf2c394d0428d0ed59b 290 Pfam PF00551 Formyl transferase 93 269 3.3E-38 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CU254_RS00970 09bb8355c8237bf2c394d0428d0ed59b 290 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 8 290 9.6E-96 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CU254_RS00970 09bb8355c8237bf2c394d0428d0ed59b 290 SUPERFAMILY SSF55021 5 86 3.04E-14 T 28-03-2018 CU254_RS00970 09bb8355c8237bf2c394d0428d0ed59b 290 PIRSF PIRSF036480 4 290 3.1E-107 T 28-03-2018 CU254_RS00970 09bb8355c8237bf2c394d0428d0ed59b 290 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 4 290 46.855 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CU254_RS06125 d9e01e07fdf2e9c9fa53e168aa2f208a 457 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 29 437 1.4E-32 T 28-03-2018 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 CU254_RS06125 d9e01e07fdf2e9c9fa53e168aa2f208a 457 PIRSF PIRSF002744 4 455 1.8E-117 T 28-03-2018 IPR026030 Purine-cytosine permease Fcy2/21/22 GO:0005215|GO:0016021|GO:0055085 CU254_RS30360 298b8414108d30281fb9e1f968c19732 274 Pfam PF13714 Phosphoenolpyruvate phosphomutase 11 252 2.8E-71 T 28-03-2018 CU254_RS30360 298b8414108d30281fb9e1f968c19732 274 Gene3D G3DSA:3.20.20.60 1 265 3.4E-55 T 28-03-2018 CU254_RS30360 298b8414108d30281fb9e1f968c19732 274 SUPERFAMILY SSF51621 5 261 5.38E-60 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CU254_RS15630 10bddd93aefb7cbc572bc59fddf8957c 227 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 113 119 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CU254_RS15630 10bddd93aefb7cbc572bc59fddf8957c 227 Gene3D G3DSA:3.40.50.150 20 193 6.7E-23 T 28-03-2018 CU254_RS15630 10bddd93aefb7cbc572bc59fddf8957c 227 SUPERFAMILY SSF53335 17 188 9.6E-27 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS15630 10bddd93aefb7cbc572bc59fddf8957c 227 Pfam PF05175 Methyltransferase small domain 20 167 4.4E-13 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 CU254_RS35235 893819723be2d56629e4a750798c3e7e 208 Pfam PF06737 Transglycosylase-like domain 39 110 4.9E-34 T 28-03-2018 IPR010618 Transglycosylase-like CU254_RS35235 893819723be2d56629e4a750798c3e7e 208 Gene3D G3DSA:3.10.350.10 153 207 6.2E-12 T 28-03-2018 CU254_RS35235 893819723be2d56629e4a750798c3e7e 208 SUPERFAMILY SSF54106 161 205 2.88E-6 T 28-03-2018 IPR018392 LysM domain CU254_RS35235 893819723be2d56629e4a750798c3e7e 208 SUPERFAMILY SSF53955 38 115 2.79E-32 T 28-03-2018 IPR023346 Lysozyme-like domain CU254_RS35235 893819723be2d56629e4a750798c3e7e 208 Pfam PF01476 LysM domain 161 205 3.1E-10 T 28-03-2018 IPR018392 LysM domain CU254_RS35235 893819723be2d56629e4a750798c3e7e 208 Gene3D G3DSA:1.10.530.10 6 117 9.6E-32 T 28-03-2018 CU254_RS35235 893819723be2d56629e4a750798c3e7e 208 SMART SM00257 160 208 2.3E-9 T 28-03-2018 IPR018392 LysM domain CU254_RS21510 4efcad3ad52410d4b2fa62b47825c830 303 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 13 303 53.012 T 28-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CU254_RS21510 4efcad3ad52410d4b2fa62b47825c830 303 PIRSF PIRSF029271 4 303 1.5E-150 T 28-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CU254_RS21510 4efcad3ad52410d4b2fa62b47825c830 303 ProSitePatterns PS01235 PdxS/SNZ family signature. 214 232 - T 28-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CU254_RS21510 4efcad3ad52410d4b2fa62b47825c830 303 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 18 303 1.6E-144 T 28-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CU254_RS21510 4efcad3ad52410d4b2fa62b47825c830 303 SUPERFAMILY SSF51366 27 276 1.08E-61 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CU254_RS21510 4efcad3ad52410d4b2fa62b47825c830 303 Gene3D G3DSA:3.20.20.70 27 280 4.2E-67 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS21510 4efcad3ad52410d4b2fa62b47825c830 303 Pfam PF01680 SOR/SNZ family 16 221 2.6E-107 T 28-03-2018 IPR033755 PdxS/SNZ N-terminal domain KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CU254_RS34365 bb88b87f9ad0e4e6ebdff4b2336d3ea9 319 Gene3D G3DSA:3.10.450.50 177 309 1.4E-17 T 28-03-2018 CU254_RS34365 bb88b87f9ad0e4e6ebdff4b2336d3ea9 319 TIGRFAM TIGR02960 SigX5: RNA polymerase sigma-70 factor, TIGR02960 family 13 312 5.3E-91 T 28-03-2018 IPR014305 RNA polymerase sigma-G type, actinobacteria CU254_RS34365 bb88b87f9ad0e4e6ebdff4b2336d3ea9 319 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 42 73 - T 28-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS34365 bb88b87f9ad0e4e6ebdff4b2336d3ea9 319 Gene3D G3DSA:1.10.10.10 114 176 4.0E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS34365 bb88b87f9ad0e4e6ebdff4b2336d3ea9 319 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 15 184 1.3E-23 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS34365 bb88b87f9ad0e4e6ebdff4b2336d3ea9 319 SUPERFAMILY SSF88946 4 94 1.41E-27 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS34365 bb88b87f9ad0e4e6ebdff4b2336d3ea9 319 Gene3D G3DSA:1.10.1740.10 2 113 1.2E-27 T 28-03-2018 CU254_RS34365 bb88b87f9ad0e4e6ebdff4b2336d3ea9 319 SUPERFAMILY SSF88659 131 187 5.98E-13 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS34365 bb88b87f9ad0e4e6ebdff4b2336d3ea9 319 Pfam PF04542 Sigma-70 region 2 20 87 4.6E-19 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS34365 bb88b87f9ad0e4e6ebdff4b2336d3ea9 319 Pfam PF12680 SnoaL-like domain 199 259 1.5E-7 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CU254_RS34365 bb88b87f9ad0e4e6ebdff4b2336d3ea9 319 SUPERFAMILY SSF54427 195 306 6.19E-16 T 28-03-2018 IPR032710 NTF2-like domain CU254_RS34365 bb88b87f9ad0e4e6ebdff4b2336d3ea9 319 Pfam PF08281 Sigma-70, region 4 131 182 8.7E-15 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS28050 01713079048cac986d7c77606482c931 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 224 1.7E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS28050 01713079048cac986d7c77606482c931 227 SUPERFAMILY SSF52172 1 184 1.02E-36 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS28050 01713079048cac986d7c77606482c931 227 SMART SM00448 2 110 7.6E-36 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS28050 01713079048cac986d7c77606482c931 227 Pfam PF00072 Response regulator receiver domain 4 111 1.7E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS28050 01713079048cac986d7c77606482c931 227 Gene3D G3DSA:1.10.10.10 117 227 3.4E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS28050 01713079048cac986d7c77606482c931 227 Gene3D G3DSA:3.40.50.2300 1 116 1.9E-32 T 28-03-2018 CU254_RS28050 01713079048cac986d7c77606482c931 227 SMART SM00862 145 224 2.5E-20 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS16220 6a3871669f29f5ee91f9a9049a36654a 326 Pfam PF00881 Nitroreductase family 222 302 1.6E-6 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CU254_RS16220 6a3871669f29f5ee91f9a9049a36654a 326 Gene3D G3DSA:3.40.109.30 7 86 3.0E-9 T 28-03-2018 CU254_RS16220 6a3871669f29f5ee91f9a9049a36654a 326 SUPERFAMILY SSF55469 11 85 6.15E-8 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CU254_RS16220 6a3871669f29f5ee91f9a9049a36654a 326 SUPERFAMILY SSF55469 117 173 1.06E-11 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CU254_RS16220 6a3871669f29f5ee91f9a9049a36654a 326 SUPERFAMILY SSF55469 223 319 1.06E-11 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CU254_RS16220 6a3871669f29f5ee91f9a9049a36654a 326 Gene3D G3DSA:3.40.109.10 102 318 9.1E-30 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CU254_RS09675 4376cfea615dfd8a9ad67da21546498e 250 Gene3D G3DSA:3.40.50.300 6 249 1.4E-76 T 28-03-2018 CU254_RS09675 4376cfea615dfd8a9ad67da21546498e 250 PIRSF PIRSF039085 6 249 7.1E-112 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CU254_RS09675 4376cfea615dfd8a9ad67da21546498e 250 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS09675 4376cfea615dfd8a9ad67da21546498e 250 SMART SM00382 34 221 9.3E-19 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS09675 4376cfea615dfd8a9ad67da21546498e 250 SUPERFAMILY SSF52540 9 243 1.13E-79 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS09675 4376cfea615dfd8a9ad67da21546498e 250 Pfam PF00005 ABC transporter 25 173 3.8E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS33370 27c486d3e08fe67885f5f8fabc7236fe 297 Gene3D G3DSA:3.40.710.10 2 295 3.3E-32 T 28-03-2018 CU254_RS33370 27c486d3e08fe67885f5f8fabc7236fe 297 Pfam PF13354 Beta-lactamase enzyme family 34 263 4.1E-51 T 28-03-2018 CU254_RS33370 27c486d3e08fe67885f5f8fabc7236fe 297 SUPERFAMILY SSF56601 180 291 3.15E-37 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CU254_RS33370 27c486d3e08fe67885f5f8fabc7236fe 297 SUPERFAMILY SSF56601 34 149 3.15E-37 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CU254_RS13065 618280862c783d8f4fec8dcdaf189666 359 Pfam PF00226 DnaJ domain 3 61 3.7E-17 T 28-03-2018 IPR001623 DnaJ domain CU254_RS13065 618280862c783d8f4fec8dcdaf189666 359 Gene3D G3DSA:1.10.287.110 1 74 8.7E-20 T 28-03-2018 IPR001623 DnaJ domain CU254_RS13065 618280862c783d8f4fec8dcdaf189666 359 Pfam PF08378 Nuclease-related domain 196 270 8.1E-5 T 28-03-2018 IPR011528 Nuclease-related domain, NERD CU254_RS13065 618280862c783d8f4fec8dcdaf189666 359 PRINTS PR00625 DnaJ domain signature 23 38 8.5E-7 T 28-03-2018 IPR001623 DnaJ domain CU254_RS13065 618280862c783d8f4fec8dcdaf189666 359 PRINTS PR00625 DnaJ domain signature 5 23 8.5E-7 T 28-03-2018 IPR001623 DnaJ domain CU254_RS13065 618280862c783d8f4fec8dcdaf189666 359 SMART SM00271 2 56 6.3E-18 T 28-03-2018 IPR001623 DnaJ domain CU254_RS13065 618280862c783d8f4fec8dcdaf189666 359 ProSitePatterns PS00636 Nt-dnaJ domain signature. 41 60 - T 28-03-2018 IPR018253 DnaJ domain, conserved site CU254_RS13065 618280862c783d8f4fec8dcdaf189666 359 SUPERFAMILY SSF46565 3 67 1.3E-21 T 28-03-2018 IPR001623 DnaJ domain CU254_RS29840 8d92063c1ae4839ab79cddc07606d10e 422 Gene3D G3DSA:3.30.565.10 280 422 3.7E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS29840 8d92063c1ae4839ab79cddc07606d10e 422 SUPERFAMILY SSF55874 317 421 1.78E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS29840 8d92063c1ae4839ab79cddc07606d10e 422 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 334 421 3.8E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS39760 2646ae65c68b398477e9fd50075bc251 215 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 206 4.4E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS39760 2646ae65c68b398477e9fd50075bc251 215 Gene3D G3DSA:1.10.3720.10 2 211 8.4E-22 T 28-03-2018 CU254_RS39760 2646ae65c68b398477e9fd50075bc251 215 SUPERFAMILY SSF161098 11 198 7.98E-29 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS27670 11e3ba5e21f1daa625a9daf3410691e5 443 SMART SM00564 75 106 0.0051 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CU254_RS27670 11e3ba5e21f1daa625a9daf3410691e5 443 SMART SM00564 379 412 90.0 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CU254_RS27670 11e3ba5e21f1daa625a9daf3410691e5 443 Pfam PF13360 PQQ-like domain 360 436 3.2E-4 T 28-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat CU254_RS27670 11e3ba5e21f1daa625a9daf3410691e5 443 Pfam PF13360 PQQ-like domain 62 193 3.6E-8 T 28-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat CU254_RS27670 11e3ba5e21f1daa625a9daf3410691e5 443 Gene3D G3DSA:2.140.10.10 28 324 9.3E-27 T 28-03-2018 CU254_RS27670 11e3ba5e21f1daa625a9daf3410691e5 443 SUPERFAMILY SSF50998 364 436 5.49E-8 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CU254_RS27670 11e3ba5e21f1daa625a9daf3410691e5 443 Gene3D G3DSA:2.140.10.10 327 443 6.8E-11 T 28-03-2018 CU254_RS27670 11e3ba5e21f1daa625a9daf3410691e5 443 SUPERFAMILY SSF50998 32 318 1.57E-21 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CU254_RS12825 506227f299678993bfef91b5ffc42e1d 407 Pfam PF16911 Phthiocerol/phthiodiolone dimycocerosyl transferase C-terminus 280 393 7.7E-12 T 28-03-2018 IPR031641 Phthiocerol/phthiodiolone dimycocerosyl transferase, C-terminal CU254_RS12825 506227f299678993bfef91b5ffc42e1d 407 Pfam PF00668 Condensation domain 21 148 4.8E-5 T 28-03-2018 IPR001242 Condensation domain CU254_RS12825 506227f299678993bfef91b5ffc42e1d 407 Gene3D G3DSA:3.30.559.10 4 176 2.4E-8 T 28-03-2018 CU254_RS12825 506227f299678993bfef91b5ffc42e1d 407 SUPERFAMILY SSF52777 188 400 4.22E-16 T 28-03-2018 CU254_RS12825 506227f299678993bfef91b5ffc42e1d 407 SUPERFAMILY SSF52777 20 143 3.11E-11 T 28-03-2018 CU254_RS12825 506227f299678993bfef91b5ffc42e1d 407 Gene3D G3DSA:3.30.559.10 177 307 5.6E-4 T 28-03-2018 CU254_RS13465 70941b851129cf06fe37efcd46bd6058 319 SUPERFAMILY SSF161098 94 299 7.52E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS13465 70941b851129cf06fe37efcd46bd6058 319 Gene3D G3DSA:1.10.3720.10 4 305 3.1E-34 T 28-03-2018 CU254_RS13465 70941b851129cf06fe37efcd46bd6058 319 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 316 2.2E-34 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS39425 f34c40f1fcd42707c7b59566499d3f7b 328 Pfam PF00296 Luciferase-like monooxygenase 2 291 8.7E-48 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS39425 f34c40f1fcd42707c7b59566499d3f7b 328 SUPERFAMILY SSF51679 1 322 5.1E-64 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS39425 f34c40f1fcd42707c7b59566499d3f7b 328 Gene3D G3DSA:3.20.20.30 1 323 9.4E-74 T 28-03-2018 CU254_RS02865 55d9f188d8bf6a1f583d0157e8335444 184 Gene3D G3DSA:1.10.357.10 2 184 1.2E-32 T 28-03-2018 CU254_RS02865 55d9f188d8bf6a1f583d0157e8335444 184 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 2.1E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS02865 55d9f188d8bf6a1f583d0157e8335444 184 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 2.1E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS02865 55d9f188d8bf6a1f583d0157e8335444 184 SUPERFAMILY SSF48498 83 184 5.29E-20 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS02865 55d9f188d8bf6a1f583d0157e8335444 184 SUPERFAMILY SSF46689 7 86 4.49E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS02865 55d9f188d8bf6a1f583d0157e8335444 184 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 64 2.6E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS09150 d3fee2767b4df1be30e1ec22fd873bdf 468 Pfam PF05108 Type VII secretion system ESX-1, transport TM domain B 3 461 4.2E-79 T 28-03-2018 IPR007795 Type VII secretion system EccB CU254_RS09150 d3fee2767b4df1be30e1ec22fd873bdf 468 TIGRFAM TIGR03919 T7SS_EccB: type VII secretion protein EccB 3 456 1.8E-79 T 28-03-2018 IPR007795 Type VII secretion system EccB CU254_RS04015 8b655397cb93d1088b52c9b029923ae4 678 Gene3D G3DSA:3.40.50.740 55 243 1.8E-39 T 28-03-2018 CU254_RS04015 8b655397cb93d1088b52c9b029923ae4 678 Gene3D G3DSA:2.40.40.20 524 676 4.1E-40 T 28-03-2018 CU254_RS04015 8b655397cb93d1088b52c9b029923ae4 678 SMART SM00926 1 49 8.7E-8 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS04015 8b655397cb93d1088b52c9b029923ae4 678 Gene3D G3DSA:3.40.50.740 244 523 8.1E-69 T 28-03-2018 CU254_RS04015 8b655397cb93d1088b52c9b029923ae4 678 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 4 43 4.8E-5 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS04015 8b655397cb93d1088b52c9b029923ae4 678 Gene3D G3DSA:2.20.25.90 1 50 1.2E-14 T 28-03-2018 CU254_RS04015 8b655397cb93d1088b52c9b029923ae4 678 Pfam PF01568 Molydopterin dinucleotide binding domain 564 670 8.8E-28 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CU254_RS04015 8b655397cb93d1088b52c9b029923ae4 678 SUPERFAMILY SSF50692 525 676 1.81E-43 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain CU254_RS04015 8b655397cb93d1088b52c9b029923ae4 678 SUPERFAMILY SSF53706 3 563 1.13E-162 T 28-03-2018 CU254_RS04015 8b655397cb93d1088b52c9b029923ae4 678 Pfam PF00384 Molybdopterin oxidoreductase 52 470 2.0E-74 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS17325 64c8afd80a421e0299895bf618f89d6e 276 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 117 255 2.6E-20 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CU254_RS17325 64c8afd80a421e0299895bf618f89d6e 276 Pfam PF12840 Helix-turn-helix domain 2 62 1.1E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS17325 64c8afd80a421e0299895bf618f89d6e 276 Gene3D G3DSA:3.30.530.20 106 260 1.3E-27 T 28-03-2018 IPR023393 START-like domain CU254_RS17325 64c8afd80a421e0299895bf618f89d6e 276 SUPERFAMILY SSF55961 106 260 1.88E-30 T 28-03-2018 CU254_RS17325 64c8afd80a421e0299895bf618f89d6e 276 Gene3D G3DSA:1.10.10.10 1 91 1.1E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS17325 64c8afd80a421e0299895bf618f89d6e 276 SMART SM00418 3 82 7.8E-15 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS17325 64c8afd80a421e0299895bf618f89d6e 276 SUPERFAMILY SSF46785 1 94 3.2E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS17325 64c8afd80a421e0299895bf618f89d6e 276 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 38 53 2.4E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS17325 64c8afd80a421e0299895bf618f89d6e 276 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 53 68 2.4E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS17325 64c8afd80a421e0299895bf618f89d6e 276 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 5 20 2.4E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS27705 1be29150de32f32e47d2e62247c6b788 386 SUPERFAMILY SSF56601 34 367 8.53E-63 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CU254_RS27705 1be29150de32f32e47d2e62247c6b788 386 Gene3D G3DSA:3.40.710.10 12 376 6.3E-65 T 28-03-2018 CU254_RS27705 1be29150de32f32e47d2e62247c6b788 386 Pfam PF00144 Beta-lactamase 42 366 1.1E-51 T 28-03-2018 IPR001466 Beta-lactamase-related CU254_RS41370 78386bd9b64f7edb2a67d4309aa737cf 215 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 83 172 3.4E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CU254_RS41370 78386bd9b64f7edb2a67d4309aa737cf 215 Gene3D G3DSA:3.40.50.1000 1 215 5.9E-27 T 28-03-2018 IPR023214 HAD-like domain CU254_RS41370 78386bd9b64f7edb2a67d4309aa737cf 215 SUPERFAMILY SSF56784 2 212 6.27E-33 T 28-03-2018 IPR023214 HAD-like domain CU254_RS41370 78386bd9b64f7edb2a67d4309aa737cf 215 Pfam PF13419 Haloacid dehalogenase-like hydrolase 78 174 2.6E-10 T 28-03-2018 IPR023214 HAD-like domain CU254_RS30525 fc3db438abde2bb9bcb56a6139aaa894 276 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 271 2.6E-26 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS30525 fc3db438abde2bb9bcb56a6139aaa894 276 SUPERFAMILY SSF161098 68 255 1.18E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS30525 fc3db438abde2bb9bcb56a6139aaa894 276 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 4 42 3.1E-6 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CU254_RS30525 fc3db438abde2bb9bcb56a6139aaa894 276 Gene3D G3DSA:1.10.3720.10 13 276 3.4E-39 T 28-03-2018 CU254_RS07475 ed9ad17cd150a8cfdf94300dfc24b04e 342 Gene3D G3DSA:3.40.50.2300 33 148 1.7E-20 T 28-03-2018 CU254_RS07475 ed9ad17cd150a8cfdf94300dfc24b04e 342 SUPERFAMILY SSF53822 34 334 7.7E-57 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CU254_RS07475 ed9ad17cd150a8cfdf94300dfc24b04e 342 Gene3D G3DSA:3.40.50.2300 149 289 6.0E-25 T 28-03-2018 CU254_RS07475 ed9ad17cd150a8cfdf94300dfc24b04e 342 Pfam PF13407 Periplasmic binding protein domain 40 297 3.3E-47 T 28-03-2018 IPR025997 Periplasmic binding protein CU254_RS09105 31ee6dec31745233fb587f541f4bab89 107 PIRSF PIRSF004555 6 106 6.6E-15 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CU254_RS09105 31ee6dec31745233fb587f541f4bab89 107 SUPERFAMILY SSF82607 10 98 9.16E-14 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CU254_RS09105 31ee6dec31745233fb587f541f4bab89 107 Pfam PF02575 YbaB/EbfC DNA-binding family 15 100 6.6E-17 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CU254_RS09105 31ee6dec31745233fb587f541f4bab89 107 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 9 97 4.7E-14 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CU254_RS09105 31ee6dec31745233fb587f541f4bab89 107 Gene3D G3DSA:3.30.1310.10 2 105 1.4E-20 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CU254_RS18320 bd9a7594517754b2e0d5b90bd399b546 128 Pfam PF14230 Domain of unknown function (DUF4333) 44 120 6.3E-19 T 28-03-2018 IPR025637 Domain of unknown function DUF4333 CU254_RS35045 82de414842816a72889284d0ca06d984 117 Gene3D G3DSA:3.30.1460.30 3 107 8.0E-9 T 28-03-2018 CU254_RS35045 82de414842816a72889284d0ca06d984 117 SUPERFAMILY SSF142906 3 112 1.1E-17 T 28-03-2018 CU254_RS35045 82de414842816a72889284d0ca06d984 117 Pfam PF04237 YjbR 12 104 1.7E-15 T 28-03-2018 IPR007351 Uncharacterised protein YjbR CU254_RS28960 e177ae82d88f20d1279bfaba48db4ac5 251 Gene3D G3DSA:3.40.190.10 127 208 1.8E-13 T 28-03-2018 CU254_RS28960 e177ae82d88f20d1279bfaba48db4ac5 251 Pfam PF03466 LysR substrate binding domain 34 229 1.2E-27 T 28-03-2018 IPR005119 LysR, substrate-binding CU254_RS28960 e177ae82d88f20d1279bfaba48db4ac5 251 SUPERFAMILY SSF53850 34 241 1.0E-32 T 28-03-2018 CU254_RS28960 e177ae82d88f20d1279bfaba48db4ac5 251 Gene3D G3DSA:3.40.190.10 30 126 1.1E-20 T 28-03-2018 CU254_RS28485 bd4991d84b22211e6679f5799fbaa292 341 Gene3D G3DSA:3.90.1150.10 225 338 1.1E-26 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS28485 bd4991d84b22211e6679f5799fbaa292 341 SUPERFAMILY SSF53383 15 336 1.85E-59 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS28485 bd4991d84b22211e6679f5799fbaa292 341 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 194 207 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CU254_RS28485 bd4991d84b22211e6679f5799fbaa292 341 Gene3D G3DSA:3.40.640.10 43 224 4.6E-27 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS28485 bd4991d84b22211e6679f5799fbaa292 341 Pfam PF00155 Aminotransferase class I and II 26 333 2.5E-33 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CU254_RS22200 cd9937e24b5785728062e131c1d1932d 293 SUPERFAMILY SSF46689 190 241 2.0E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS22200 cd9937e24b5785728062e131c1d1932d 293 Pfam PF12833 Helix-turn-helix domain 213 291 2.5E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS22200 cd9937e24b5785728062e131c1d1932d 293 SUPERFAMILY SSF46689 243 292 4.93E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS22200 cd9937e24b5785728062e131c1d1932d 293 SMART SM00342 207 290 3.6E-26 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS22200 cd9937e24b5785728062e131c1d1932d 293 Gene3D G3DSA:1.10.10.60 247 293 2.8E-10 T 28-03-2018 CU254_RS22200 cd9937e24b5785728062e131c1d1932d 293 Gene3D G3DSA:1.10.10.60 185 246 3.3E-16 T 28-03-2018 CU254_RS21435 5b7470a2685b6ee4592a72980009ab9b 340 ProSitePatterns PS00622 LuxR-type HTH domain signature. 298 325 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS21435 5b7470a2685b6ee4592a72980009ab9b 340 Gene3D G3DSA:1.10.10.10 171 339 2.9E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS21435 5b7470a2685b6ee4592a72980009ab9b 340 Gene3D G3DSA:3.30.450.40 6 170 9.7E-7 T 28-03-2018 IPR029016 GAF domain-like CU254_RS21435 5b7470a2685b6ee4592a72980009ab9b 340 Pfam PF00196 Bacterial regulatory proteins, luxR family 283 336 5.9E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS21435 5b7470a2685b6ee4592a72980009ab9b 340 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 284 298 8.7E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS21435 5b7470a2685b6ee4592a72980009ab9b 340 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 298 314 8.7E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS21435 5b7470a2685b6ee4592a72980009ab9b 340 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 314 326 8.7E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS21435 5b7470a2685b6ee4592a72980009ab9b 340 SMART SM00421 281 338 2.5E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS21435 5b7470a2685b6ee4592a72980009ab9b 340 SUPERFAMILY SSF46894 276 337 1.6E-16 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS37785 4dfc19f59a14623436d74d1d60f7e8cb 267 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 31 247 2.2E-50 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CU254_RS37785 4dfc19f59a14623436d74d1d60f7e8cb 267 SUPERFAMILY SSF53850 1 248 5.0E-52 T 28-03-2018 CU254_RS37785 4dfc19f59a14623436d74d1d60f7e8cb 267 Gene3D G3DSA:3.40.190.10 151 260 4.3E-10 T 28-03-2018 CU254_RS37785 4dfc19f59a14623436d74d1d60f7e8cb 267 SMART SM00062 30 249 1.3E-46 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CU254_RS37785 4dfc19f59a14623436d74d1d60f7e8cb 267 Gene3D G3DSA:3.40.190.10 26 150 2.0E-28 T 28-03-2018 CU254_RS35410 b6f5016cb9894bd4e73cad3dca9493ea 419 Gene3D G3DSA:1.20.1250.20 1 200 1.2E-12 T 28-03-2018 CU254_RS35410 b6f5016cb9894bd4e73cad3dca9493ea 419 Gene3D G3DSA:1.20.1250.20 201 396 6.1E-18 T 28-03-2018 CU254_RS35410 b6f5016cb9894bd4e73cad3dca9493ea 419 Pfam PF05977 Transmembrane secretion effector 4 401 1.6E-23 T 28-03-2018 IPR010290 Transmembrane secretion effector CU254_RS35410 b6f5016cb9894bd4e73cad3dca9493ea 419 SUPERFAMILY SSF103473 6 394 3.92E-38 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS32465 a366b75ee5d1f4f303f3cb5d914644de 261 Pfam PF01614 Bacterial transcriptional regulator 132 254 4.5E-35 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal CU254_RS32465 a366b75ee5d1f4f303f3cb5d914644de 261 Pfam PF09339 IclR helix-turn-helix domain 16 65 2.0E-15 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS32465 a366b75ee5d1f4f303f3cb5d914644de 261 Gene3D G3DSA:3.30.450.40 85 261 2.1E-52 T 28-03-2018 IPR029016 GAF domain-like CU254_RS32465 a366b75ee5d1f4f303f3cb5d914644de 261 SUPERFAMILY SSF55781 71 259 4.45E-50 T 28-03-2018 IPR029016 GAF domain-like CU254_RS32465 a366b75ee5d1f4f303f3cb5d914644de 261 SUPERFAMILY SSF46785 14 85 7.31E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS32465 a366b75ee5d1f4f303f3cb5d914644de 261 Gene3D G3DSA:1.10.10.10 1 74 2.5E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS32465 a366b75ee5d1f4f303f3cb5d914644de 261 SMART SM00346 14 103 3.2E-21 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS25030 7c880c4a579ceca338c6ea5f45877b1f 264 SUPERFAMILY SSF51735 13 247 4.38E-73 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS25030 7c880c4a579ceca338c6ea5f45877b1f 264 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 12 178 0.0095 T 28-03-2018 CU254_RS25030 7c880c4a579ceca338c6ea5f45877b1f 264 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS25030 7c880c4a579ceca338c6ea5f45877b1f 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 2.5E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS25030 7c880c4a579ceca338c6ea5f45877b1f 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 2.5E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS25030 7c880c4a579ceca338c6ea5f45877b1f 264 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 2.5E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS25030 7c880c4a579ceca338c6ea5f45877b1f 264 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 246 3.8E-61 T 28-03-2018 CU254_RS25030 7c880c4a579ceca338c6ea5f45877b1f 264 Gene3D G3DSA:3.40.50.720 45 258 6.7E-65 T 28-03-2018 CU254_RS25030 7c880c4a579ceca338c6ea5f45877b1f 264 Gene3D G3DSA:3.40.50.720 10 44 1.3E-4 T 28-03-2018 CU254_RS25030 7c880c4a579ceca338c6ea5f45877b1f 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 2.3E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS25030 7c880c4a579ceca338c6ea5f45877b1f 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 2.3E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS25030 7c880c4a579ceca338c6ea5f45877b1f 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 2.3E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS25030 7c880c4a579ceca338c6ea5f45877b1f 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 2.3E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS25030 7c880c4a579ceca338c6ea5f45877b1f 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 2.3E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS25030 7c880c4a579ceca338c6ea5f45877b1f 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 2.3E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS36970 2be7239eb3495f64b79ebbddcef16828 305 SUPERFAMILY SSF51735 5 264 3.1E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS36970 2be7239eb3495f64b79ebbddcef16828 305 Gene3D G3DSA:3.40.50.720 3 273 1.2E-30 T 28-03-2018 CU254_RS36970 2be7239eb3495f64b79ebbddcef16828 305 Pfam PF00106 short chain dehydrogenase 8 213 1.6E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS36970 2be7239eb3495f64b79ebbddcef16828 305 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 93 104 1.3E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS36970 2be7239eb3495f64b79ebbddcef16828 305 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.3E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS36970 2be7239eb3495f64b79ebbddcef16828 305 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 194 1.3E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS14870 34ab36c175b3a6460f0f1a5a68bb4d05 100 SMART SM00530 32 92 9.8E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS14870 34ab36c175b3a6460f0f1a5a68bb4d05 100 Pfam PF13560 Helix-turn-helix domain 30 91 2.0E-11 T 28-03-2018 CU254_RS14870 34ab36c175b3a6460f0f1a5a68bb4d05 100 Gene3D G3DSA:1.10.260.40 28 99 1.8E-16 T 28-03-2018 CU254_RS14870 34ab36c175b3a6460f0f1a5a68bb4d05 100 SUPERFAMILY SSF47413 29 96 1.55E-12 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS38895 750b952e31ec52b5d3acd2042310b3ed 770 SUPERFAMILY SSF56601 318 688 1.67E-63 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CU254_RS38895 750b952e31ec52b5d3acd2042310b3ed 770 Pfam PF00912 Transglycosylase 115 275 2.8E-49 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CU254_RS38895 750b952e31ec52b5d3acd2042310b3ed 770 Gene3D G3DSA:3.40.710.10 294 722 1.2E-68 T 28-03-2018 CU254_RS38895 750b952e31ec52b5d3acd2042310b3ed 770 SUPERFAMILY SSF53955 94 293 9.84E-58 T 28-03-2018 IPR023346 Lysozyme-like domain CU254_RS38895 750b952e31ec52b5d3acd2042310b3ed 770 Gene3D G3DSA:1.10.3810.10 97 293 1.8E-60 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CU254_RS38895 750b952e31ec52b5d3acd2042310b3ed 770 Pfam PF00905 Penicillin binding protein transpeptidase domain 368 637 5.7E-24 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CU254_RS39405 2cd592cea04f7d265f984f911690144d 320 Gene3D G3DSA:1.20.1540.10 83 264 7.0E-39 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CU254_RS39405 2cd592cea04f7d265f984f911690144d 320 Pfam PF01694 Rhomboid family 132 263 3.2E-32 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CU254_RS39405 2cd592cea04f7d265f984f911690144d 320 SUPERFAMILY SSF144091 83 269 7.98E-41 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CU254_RS05715 28dd73f935bd6415da8073c656d79ef5 370 SUPERFAMILY SSF47384 123 203 1.63E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS05715 28dd73f935bd6415da8073c656d79ef5 370 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 250 357 1.4E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS05715 28dd73f935bd6415da8073c656d79ef5 370 Gene3D G3DSA:3.30.565.10 204 359 5.4E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS05715 28dd73f935bd6415da8073c656d79ef5 370 SMART SM00388 140 204 3.5E-8 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS05715 28dd73f935bd6415da8073c656d79ef5 370 Pfam PF00512 His Kinase A (phospho-acceptor) domain 141 203 1.1E-8 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS05715 28dd73f935bd6415da8073c656d79ef5 370 PRINTS PR00344 Bacterial sensor protein C-terminal signature 284 298 1.8E-5 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS05715 28dd73f935bd6415da8073c656d79ef5 370 PRINTS PR00344 Bacterial sensor protein C-terminal signature 319 337 1.8E-5 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS05715 28dd73f935bd6415da8073c656d79ef5 370 SUPERFAMILY SSF55874 207 356 2.1E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS05715 28dd73f935bd6415da8073c656d79ef5 370 SMART SM00387 246 359 3.2E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS05715 28dd73f935bd6415da8073c656d79ef5 370 SMART SM00304 86 139 8.2E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS05715 28dd73f935bd6415da8073c656d79ef5 370 Pfam PF00672 HAMP domain 87 135 2.9E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS05715 28dd73f935bd6415da8073c656d79ef5 370 Gene3D G3DSA:1.10.287.130 130 200 4.7E-11 T 28-03-2018 CU254_RS05715 28dd73f935bd6415da8073c656d79ef5 370 SUPERFAMILY SSF158472 88 135 8.11E-8 T 28-03-2018 CU254_RS35950 e8b047a8db5a166c3d72770d06c2a00e 201 SUPERFAMILY SSF88659 126 188 6.98E-12 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS35950 e8b047a8db5a166c3d72770d06c2a00e 201 SUPERFAMILY SSF88946 28 105 2.2E-16 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS35950 e8b047a8db5a166c3d72770d06c2a00e 201 Gene3D G3DSA:1.10.1740.10 26 99 4.0E-17 T 28-03-2018 CU254_RS35950 e8b047a8db5a166c3d72770d06c2a00e 201 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 29 188 8.3E-23 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS35950 e8b047a8db5a166c3d72770d06c2a00e 201 Pfam PF08281 Sigma-70, region 4 135 186 1.2E-10 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS35950 e8b047a8db5a166c3d72770d06c2a00e 201 Pfam PF04542 Sigma-70 region 2 33 100 4.6E-13 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS35950 e8b047a8db5a166c3d72770d06c2a00e 201 Gene3D G3DSA:1.10.10.10 100 199 1.5E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS41470 452abeee9e02c5d75f8f2d561a9d7d59 359 Gene3D G3DSA:3.90.1150.10 247 346 2.5E-18 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS41470 452abeee9e02c5d75f8f2d561a9d7d59 359 SUPERFAMILY SSF53383 15 346 2.75E-71 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS41470 452abeee9e02c5d75f8f2d561a9d7d59 359 Gene3D G3DSA:3.40.640.10 46 246 2.3E-42 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS41470 452abeee9e02c5d75f8f2d561a9d7d59 359 Pfam PF00155 Aminotransferase class I and II 22 341 1.0E-46 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CU254_RS41470 452abeee9e02c5d75f8f2d561a9d7d59 359 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 215 224 - T 28-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 CU254_RS34235 59d611974c71259249308d07ef77a187 266 Pfam PF00455 DeoR C terminal sensor domain 76 234 1.3E-46 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain CU254_RS34235 59d611974c71259249308d07ef77a187 266 Gene3D G3DSA:3.40.50.1360 79 248 5.2E-38 T 28-03-2018 CU254_RS34235 59d611974c71259249308d07ef77a187 266 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 8.5E-8 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CU254_RS34235 59d611974c71259249308d07ef77a187 266 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 8.5E-8 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CU254_RS34235 59d611974c71259249308d07ef77a187 266 SUPERFAMILY SSF46785 5 58 7.52E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS34235 59d611974c71259249308d07ef77a187 266 SMART SM01134 74 236 3.9E-56 T 28-03-2018 CU254_RS34235 59d611974c71259249308d07ef77a187 266 SMART SM00420 6 58 9.9E-17 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CU254_RS34235 59d611974c71259249308d07ef77a187 266 Pfam PF08220 DeoR-like helix-turn-helix domain 6 58 8.0E-16 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CU254_RS34235 59d611974c71259249308d07ef77a187 266 Gene3D G3DSA:1.10.10.10 1 78 2.5E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS34235 59d611974c71259249308d07ef77a187 266 SUPERFAMILY SSF100950 76 236 1.15E-30 T 28-03-2018 CU254_RS40255 d3d11053f7b0296e69bbd0e26c457250 243 SUPERFAMILY SSF51161 8 211 1.43E-45 T 28-03-2018 IPR011004 Trimeric LpxA-like CU254_RS40255 d3d11053f7b0296e69bbd0e26c457250 243 Gene3D G3DSA:2.160.10.10 64 211 8.1E-23 T 28-03-2018 CU254_RS40255 d3d11053f7b0296e69bbd0e26c457250 243 Pfam PF13720 Udp N-acetylglucosamine O-acyltransferase; Domain 2 177 209 7.1E-6 T 28-03-2018 IPR029098 Udp N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00540+2.3.1.129|KEGG: 00620+2.3.1.12 CU254_RS40255 d3d11053f7b0296e69bbd0e26c457250 243 Gene3D G3DSA:2.160.10.10 4 63 1.7E-12 T 28-03-2018 CU254_RS40255 d3d11053f7b0296e69bbd0e26c457250 243 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 8 34 1.8E-5 T 28-03-2018 IPR001451 Hexapeptide repeat CU254_RS40255 d3d11053f7b0296e69bbd0e26c457250 243 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 103 137 4.5E-4 T 28-03-2018 IPR001451 Hexapeptide repeat CU254_RS05300 eddd23e9eecfad211c4e618ffbf916ad 150 SUPERFAMILY SSF50475 12 146 1.68E-27 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS05300 eddd23e9eecfad211c4e618ffbf916ad 150 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 16 145 5.9E-30 T 28-03-2018 IPR019920 F420-binding domain, putative CU254_RS05300 eddd23e9eecfad211c4e618ffbf916ad 150 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 12 95 7.7E-16 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CU254_RS05300 eddd23e9eecfad211c4e618ffbf916ad 150 Gene3D G3DSA:2.30.110.10 6 150 6.1E-27 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS39445 bc22de311089aca3e46a4a4edf95db59 600 Pfam PF07730 Histidine kinase 394 461 1.5E-16 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CU254_RS39445 bc22de311089aca3e46a4a4edf95db59 600 Pfam PF13796 Putative sensor 173 365 4.7E-8 T 28-03-2018 IPR025828 Putative sensor domain CU254_RS39445 bc22de311089aca3e46a4a4edf95db59 600 SUPERFAMILY SSF55874 494 581 1.39E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS39445 bc22de311089aca3e46a4a4edf95db59 600 Gene3D G3DSA:3.30.565.10 448 586 1.8E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS24745 34508c901eb11e693d336cbb3e189f0e 482 Gene3D G3DSA:2.40.50.140 411 478 3.9E-18 T 28-03-2018 CU254_RS24745 34508c901eb11e693d336cbb3e189f0e 482 SMART SM00729 176 396 1.9E-40 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CU254_RS24745 34508c901eb11e693d336cbb3e189f0e 482 Pfam PF04055 Radical SAM superfamily 182 354 1.5E-22 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CU254_RS24745 34508c901eb11e693d336cbb3e189f0e 482 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 180 200 - T 28-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 CU254_RS24745 34508c901eb11e693d336cbb3e189f0e 482 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 13 473 1.7E-119 T 28-03-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 CU254_RS24745 34508c901eb11e693d336cbb3e189f0e 482 SUPERFAMILY SSF102114 170 400 2.88E-44 T 28-03-2018 CU254_RS24745 34508c901eb11e693d336cbb3e189f0e 482 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 13 470 1.5E-100 T 28-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 CU254_RS24745 34508c901eb11e693d336cbb3e189f0e 482 Pfam PF00919 Uncharacterized protein family UPF0004 13 107 3.0E-29 T 28-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 CU254_RS24745 34508c901eb11e693d336cbb3e189f0e 482 Gene3D G3DSA:3.80.30.20 174 410 2.9E-37 T 28-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe CU254_RS24745 34508c901eb11e693d336cbb3e189f0e 482 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 12 476 57.025 T 28-03-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 CU254_RS21050 2c90bd7b33db0bcbe0ad69b625a33c4a 426 SUPERFAMILY SSF52540 5 244 9.51E-66 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS21050 2c90bd7b33db0bcbe0ad69b625a33c4a 426 Pfam PF09821 C-terminal AAA-associated domain 296 414 4.5E-39 T 28-03-2018 IPR018632 C-terminal AAA-associated domain CU254_RS21050 2c90bd7b33db0bcbe0ad69b625a33c4a 426 SMART SM00382 35 218 5.9E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS21050 2c90bd7b33db0bcbe0ad69b625a33c4a 426 Pfam PF00005 ABC transporter 26 165 2.2E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS21050 2c90bd7b33db0bcbe0ad69b625a33c4a 426 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS21050 2c90bd7b33db0bcbe0ad69b625a33c4a 426 Gene3D G3DSA:3.40.50.300 2 242 6.3E-60 T 28-03-2018 CU254_RS34000 06d9614ad4970df02afe2b2272873677 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 9.7E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS34000 06d9614ad4970df02afe2b2272873677 309 Gene3D G3DSA:3.40.190.10 80 201 3.0E-11 T 28-03-2018 CU254_RS34000 06d9614ad4970df02afe2b2272873677 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.2E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS34000 06d9614ad4970df02afe2b2272873677 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.2E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS34000 06d9614ad4970df02afe2b2272873677 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.2E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS34000 06d9614ad4970df02afe2b2272873677 309 Gene3D G3DSA:1.10.10.10 1 79 7.4E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS34000 06d9614ad4970df02afe2b2272873677 309 Pfam PF03466 LysR substrate binding domain 102 293 4.7E-10 T 28-03-2018 IPR005119 LysR, substrate-binding CU254_RS34000 06d9614ad4970df02afe2b2272873677 309 SUPERFAMILY SSF46785 2 84 3.52E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS34000 06d9614ad4970df02afe2b2272873677 309 SUPERFAMILY SSF53850 102 295 5.76E-15 T 28-03-2018 CU254_RS09485 d1f8f2a6dc9ec7d1de9e34b657478c4e 298 SUPERFAMILY SSF103481 195 295 2.75E-10 T 28-03-2018 CU254_RS09485 d1f8f2a6dc9ec7d1de9e34b657478c4e 298 SUPERFAMILY SSF103481 46 148 2.75E-7 T 28-03-2018 CU254_RS09485 d1f8f2a6dc9ec7d1de9e34b657478c4e 298 Pfam PF00892 EamA-like transporter family 15 144 4.5E-9 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CU254_RS09485 d1f8f2a6dc9ec7d1de9e34b657478c4e 298 Pfam PF00892 EamA-like transporter family 160 290 4.2E-14 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CU254_RS04170 9dd1533ad551eacd178b447598174e06 463 SUPERFAMILY SSF63411 34 255 1.0E-33 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CU254_RS04170 9dd1533ad551eacd178b447598174e06 463 SUPERFAMILY SSF63411 266 454 7.67E-35 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CU254_RS04170 9dd1533ad551eacd178b447598174e06 463 Gene3D G3DSA:3.30.830.10 255 453 3.2E-30 T 28-03-2018 CU254_RS04170 9dd1533ad551eacd178b447598174e06 463 Pfam PF00675 Insulinase (Peptidase family M16) 84 192 5.3E-9 T 28-03-2018 IPR011765 Peptidase M16, N-terminal CU254_RS04170 9dd1533ad551eacd178b447598174e06 463 Gene3D G3DSA:3.30.830.10 37 252 4.5E-34 T 28-03-2018 CU254_RS04170 9dd1533ad551eacd178b447598174e06 463 Pfam PF05193 Peptidase M16 inactive domain 202 375 3.4E-16 T 28-03-2018 IPR007863 Peptidase M16, C-terminal CU254_RS14335 2ad14253477d449c8e4d71f3c7cc2534 390 PIRSF PIRSF000138 2 382 6.8E-104 T 28-03-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 CU254_RS14335 2ad14253477d449c8e4d71f3c7cc2534 390 SUPERFAMILY SSF51395 8 196 2.32E-82 T 28-03-2018 CU254_RS14335 2ad14253477d449c8e4d71f3c7cc2534 390 SUPERFAMILY SSF51395 226 379 2.32E-82 T 28-03-2018 CU254_RS14335 2ad14253477d449c8e4d71f3c7cc2534 390 Gene3D G3DSA:3.20.20.70 6 383 7.3E-91 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS14335 2ad14253477d449c8e4d71f3c7cc2534 390 TIGRFAM TIGR03966 actino_HemFlav: heme/flavin dehydrogenase, mycofactocin system 3 386 4.5E-212 T 28-03-2018 IPR023989 Heme/flavin dehydrogenase, Rv0694 CU254_RS14335 2ad14253477d449c8e4d71f3c7cc2534 390 Pfam PF01070 FMN-dependent dehydrogenase 16 377 4.0E-107 T 28-03-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 CU254_RS25820 570cb5d2148a31ceb74b9fc534af8a00 75 Pfam PF05120 Gas vesicle protein G 7 73 9.3E-22 T 28-03-2018 IPR007804 Gas vesicle protein GvpG CU254_RS34550 5aff152d9ec8fe1651cb6eadfa0e32fb 291 Gene3D G3DSA:1.10.10.10 1 83 1.3E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS34550 5aff152d9ec8fe1651cb6eadfa0e32fb 291 Gene3D G3DSA:3.40.190.10 87 177 3.2E-24 T 28-03-2018 CU254_RS34550 5aff152d9ec8fe1651cb6eadfa0e32fb 291 SUPERFAMILY SSF46785 1 85 9.53E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS34550 5aff152d9ec8fe1651cb6eadfa0e32fb 291 SUPERFAMILY SSF53850 89 290 4.3E-44 T 28-03-2018 CU254_RS34550 5aff152d9ec8fe1651cb6eadfa0e32fb 291 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 2.2E-23 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS34550 5aff152d9ec8fe1651cb6eadfa0e32fb 291 Pfam PF03466 LysR substrate binding domain 88 290 1.2E-46 T 28-03-2018 IPR005119 LysR, substrate-binding CU254_RS34550 5aff152d9ec8fe1651cb6eadfa0e32fb 291 Gene3D G3DSA:3.40.190.10 178 265 3.6E-22 T 28-03-2018 CU254_RS34550 5aff152d9ec8fe1651cb6eadfa0e32fb 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.1E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS34550 5aff152d9ec8fe1651cb6eadfa0e32fb 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.1E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS34550 5aff152d9ec8fe1651cb6eadfa0e32fb 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.1E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS04275 50c9c6446b71e4382eaf60a8dddfeb25 392 Pfam PF02040 Arsenical pump membrane protein 24 382 8.0E-29 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CU254_RS04275 50c9c6446b71e4382eaf60a8dddfeb25 392 PRINTS PR00758 Arsenical pump membrane protein signature 86 110 4.3E-15 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CU254_RS04275 50c9c6446b71e4382eaf60a8dddfeb25 392 PRINTS PR00758 Arsenical pump membrane protein signature 331 356 4.3E-15 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CU254_RS04275 50c9c6446b71e4382eaf60a8dddfeb25 392 PRINTS PR00758 Arsenical pump membrane protein signature 159 182 4.3E-15 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CU254_RS03495 384670a0fd6e9f8e9271fb1f30eb7a27 294 Gene3D G3DSA:3.90.25.10 178 207 1.9E-9 T 28-03-2018 CU254_RS03495 384670a0fd6e9f8e9271fb1f30eb7a27 294 SUPERFAMILY SSF51735 5 292 8.07E-85 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS03495 384670a0fd6e9f8e9271fb1f30eb7a27 294 Pfam PF04321 RmlD substrate binding domain 5 292 9.1E-103 T 28-03-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 CU254_RS03495 384670a0fd6e9f8e9271fb1f30eb7a27 294 Gene3D G3DSA:3.40.50.720 3 177 3.4E-19 T 28-03-2018 CU254_RS03495 384670a0fd6e9f8e9271fb1f30eb7a27 294 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 5 293 3.3E-88 T 28-03-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 CU254_RS03495 384670a0fd6e9f8e9271fb1f30eb7a27 294 Gene3D G3DSA:3.90.25.10 208 281 1.2E-22 T 28-03-2018 CU254_RS16900 15829172afb62e04d0655b254d0cb2c2 253 Pfam PF13560 Helix-turn-helix domain 9 84 2.5E-16 T 28-03-2018 CU254_RS16900 15829172afb62e04d0655b254d0cb2c2 253 SMART SM00530 13 82 8.1E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS16900 15829172afb62e04d0655b254d0cb2c2 253 Gene3D G3DSA:1.10.260.40 6 87 1.1E-14 T 28-03-2018 CU254_RS16900 15829172afb62e04d0655b254d0cb2c2 253 SUPERFAMILY SSF47413 30 81 1.21E-7 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS25010 e69d421db028639a2c28b5b84725d04a 216 Gene3D G3DSA:3.40.50.2300 1 126 6.7E-35 T 28-03-2018 CU254_RS25010 e69d421db028639a2c28b5b84725d04a 216 ProSitePatterns PS00622 LuxR-type HTH domain signature. 168 195 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS25010 e69d421db028639a2c28b5b84725d04a 216 SMART SM00421 151 208 1.2E-23 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS25010 e69d421db028639a2c28b5b84725d04a 216 Gene3D G3DSA:1.10.10.10 127 216 1.8E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS25010 e69d421db028639a2c28b5b84725d04a 216 Pfam PF00072 Response regulator receiver domain 4 114 1.2E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS25010 e69d421db028639a2c28b5b84725d04a 216 SUPERFAMILY SSF46894 141 214 4.08E-20 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS25010 e69d421db028639a2c28b5b84725d04a 216 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 205 3.6E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS25010 e69d421db028639a2c28b5b84725d04a 216 SMART SM00448 2 115 7.3E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS25010 e69d421db028639a2c28b5b84725d04a 216 SUPERFAMILY SSF52172 2 131 5.98E-33 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS25010 e69d421db028639a2c28b5b84725d04a 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 196 6.6E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS25010 e69d421db028639a2c28b5b84725d04a 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 184 6.6E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS25010 e69d421db028639a2c28b5b84725d04a 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 168 6.6E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS08820 093f09b4f8493b8c285c99f4f793162a 267 Gene3D G3DSA:3.90.550.10 33 266 2.8E-37 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS08820 093f09b4f8493b8c285c99f4f793162a 267 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 43 262 9.0E-46 T 28-03-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CU254_RS08820 093f09b4f8493b8c285c99f4f793162a 267 SUPERFAMILY SSF53448 42 262 1.36E-41 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS32435 dce1ebdbcd5273c66b78d4b007dac720 972 SUPERFAMILY SSF52540 367 414 3.03E-78 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS32435 dce1ebdbcd5273c66b78d4b007dac720 972 SUPERFAMILY SSF52540 8 225 3.03E-78 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS32435 dce1ebdbcd5273c66b78d4b007dac720 972 SUPERFAMILY SSF81886 634 857 6.54E-72 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CU254_RS32435 dce1ebdbcd5273c66b78d4b007dac720 972 ProSitePatterns PS01312 SecA family signature. 499 514 - T 28-03-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 CU254_RS32435 dce1ebdbcd5273c66b78d4b007dac720 972 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 25 834 0.0 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CU254_RS32435 dce1ebdbcd5273c66b78d4b007dac720 972 Pfam PF07517 SecA DEAD-like domain 6 400 4.5E-128 T 28-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CU254_RS32435 dce1ebdbcd5273c66b78d4b007dac720 972 PRINTS PR00906 SecA protein signature 412 425 3.9E-69 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CU254_RS32435 dce1ebdbcd5273c66b78d4b007dac720 972 PRINTS PR00906 SecA protein signature 98 112 3.9E-69 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CU254_RS32435 dce1ebdbcd5273c66b78d4b007dac720 972 PRINTS PR00906 SecA protein signature 114 124 3.9E-69 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CU254_RS32435 dce1ebdbcd5273c66b78d4b007dac720 972 PRINTS PR00906 SecA protein signature 338 360 3.9E-69 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CU254_RS32435 dce1ebdbcd5273c66b78d4b007dac720 972 PRINTS PR00906 SecA protein signature 375 392 3.9E-69 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CU254_RS32435 dce1ebdbcd5273c66b78d4b007dac720 972 PRINTS PR00906 SecA protein signature 167 187 3.9E-69 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CU254_RS32435 dce1ebdbcd5273c66b78d4b007dac720 972 PRINTS PR00906 SecA protein signature 60 84 3.9E-69 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CU254_RS32435 dce1ebdbcd5273c66b78d4b007dac720 972 Gene3D G3DSA:3.40.50.300 416 634 3.3E-52 T 28-03-2018 CU254_RS32435 dce1ebdbcd5273c66b78d4b007dac720 972 Gene3D G3DSA:3.10.450.50 738 971 1.3E-33 T 28-03-2018 CU254_RS32435 dce1ebdbcd5273c66b78d4b007dac720 972 Gene3D G3DSA:1.10.3060.10 635 727 6.0E-26 T 28-03-2018 CU254_RS32435 dce1ebdbcd5273c66b78d4b007dac720 972 SMART SM00957 3 401 7.6E-271 T 28-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CU254_RS32435 dce1ebdbcd5273c66b78d4b007dac720 972 SUPERFAMILY SSF52540 415 632 4.76E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS32435 dce1ebdbcd5273c66b78d4b007dac720 972 Hamap MF_01382 Protein translocase subunit SecA [secA]. 2 849 19.785 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CU254_RS32435 dce1ebdbcd5273c66b78d4b007dac720 972 Pfam PF07516 SecA Wing and Scaffold domain 631 846 1.4E-65 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CU254_RS32435 dce1ebdbcd5273c66b78d4b007dac720 972 SUPERFAMILY SSF81767 259 367 1.57E-39 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CU254_RS32435 dce1ebdbcd5273c66b78d4b007dac720 972 SMART SM00958 225 357 8.5E-57 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CU254_RS32435 dce1ebdbcd5273c66b78d4b007dac720 972 Gene3D G3DSA:3.40.50.300 6 271 7.2E-52 T 28-03-2018 CU254_RS32435 dce1ebdbcd5273c66b78d4b007dac720 972 Gene3D G3DSA:3.40.50.300 309 415 7.0E-10 T 28-03-2018 CU254_RS32435 dce1ebdbcd5273c66b78d4b007dac720 972 Pfam PF01043 SecA preprotein cross-linking domain 260 357 2.9E-33 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CU254_RS03350 236205ea92b8aea191ee247bb081731c 192 SUPERFAMILY SSF55729 46 145 3.54E-13 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS03350 236205ea92b8aea191ee247bb081731c 192 Pfam PF00583 Acetyltransferase (GNAT) family 58 145 4.6E-8 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS03350 236205ea92b8aea191ee247bb081731c 192 Gene3D G3DSA:3.40.630.30 7 177 2.7E-16 T 28-03-2018 CU254_RS08125 49e41b984b3ef9cae72268397db6ef04 300 Pfam PF03466 LysR substrate binding domain 86 289 3.2E-38 T 28-03-2018 IPR005119 LysR, substrate-binding CU254_RS08125 49e41b984b3ef9cae72268397db6ef04 300 Gene3D G3DSA:1.10.10.10 1 87 2.3E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS08125 49e41b984b3ef9cae72268397db6ef04 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 2.5E-14 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS08125 49e41b984b3ef9cae72268397db6ef04 300 Gene3D G3DSA:3.40.190.10 88 177 2.7E-15 T 28-03-2018 CU254_RS08125 49e41b984b3ef9cae72268397db6ef04 300 SUPERFAMILY SSF46785 1 107 9.49E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS08125 49e41b984b3ef9cae72268397db6ef04 300 Gene3D G3DSA:3.40.190.10 178 266 6.2E-15 T 28-03-2018 CU254_RS08125 49e41b984b3ef9cae72268397db6ef04 300 SUPERFAMILY SSF53850 82 290 2.71E-34 T 28-03-2018 CU254_RS06835 dd36f75978ea427b4c0334071fc10888 191 Pfam PF07681 DoxX 35 119 1.4E-12 T 28-03-2018 IPR032808 DoxX family CU254_RS37075 f69f5a9feae56a5ecac43ca6abe67f7e 365 Gene3D G3DSA:3.40.50.2000 1 211 7.2E-46 T 28-03-2018 CU254_RS37075 f69f5a9feae56a5ecac43ca6abe67f7e 365 SUPERFAMILY SSF53756 2 347 6.8E-50 T 28-03-2018 CU254_RS37075 f69f5a9feae56a5ecac43ca6abe67f7e 365 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 80 330 1.7E-42 T 28-03-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001 CU254_RS37075 f69f5a9feae56a5ecac43ca6abe67f7e 365 Gene3D G3DSA:3.40.50.2000 212 341 2.2E-17 T 28-03-2018 CU254_RS35615 9fd8e7e6934105a6d3f7f176c88c2840 130 ProDom PD080544 SYNTHASE 4.2.1.- LYASE L-ECTOINE DEHYDRATASE N-ACETYLDIAMINOBUTYRATE ECTOINE ENZYME SYNTHASE:ECTOINE ECTC 1 117 3.0E-39 T 28-03-2018 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CU254_RS35615 9fd8e7e6934105a6d3f7f176c88c2840 130 Pfam PF06339 Ectoine synthase 2 126 2.3E-58 T 28-03-2018 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CU254_RS35615 9fd8e7e6934105a6d3f7f176c88c2840 130 SUPERFAMILY SSF51182 18 127 5.22E-20 T 28-03-2018 IPR011051 RmlC-like cupin domain CU254_RS35615 9fd8e7e6934105a6d3f7f176c88c2840 130 Gene3D G3DSA:2.60.120.10 7 128 4.1E-15 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS35615 9fd8e7e6934105a6d3f7f176c88c2840 130 Hamap MF_01255 L-ectoine synthase [ectC]. 1 127 37.58 T 28-03-2018 IPR010462 Ectoine synthase GO:0019491|GO:0033990 KEGG: 00260+4.2.1.108|KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CU254_RS02290 f20ca94d22171b7e14882c2f91bb5607 438 Pfam PF01039 Carboxyl transferase domain 45 192 1.8E-13 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 CU254_RS02290 f20ca94d22171b7e14882c2f91bb5607 438 Pfam PF01039 Carboxyl transferase domain 308 407 1.3E-9 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 CU254_RS02290 f20ca94d22171b7e14882c2f91bb5607 438 Gene3D G3DSA:3.90.226.10 220 430 7.6E-36 T 28-03-2018 CU254_RS02290 f20ca94d22171b7e14882c2f91bb5607 438 SUPERFAMILY SSF52096 2 219 1.12E-41 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS02290 f20ca94d22171b7e14882c2f91bb5607 438 SUPERFAMILY SSF52096 229 438 4.11E-43 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS02290 f20ca94d22171b7e14882c2f91bb5607 438 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 142 159 3.1E-13 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CU254_RS02290 f20ca94d22171b7e14882c2f91bb5607 438 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 105 123 3.1E-13 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CU254_RS02290 f20ca94d22171b7e14882c2f91bb5607 438 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 171 182 3.1E-13 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CU254_RS02290 f20ca94d22171b7e14882c2f91bb5607 438 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 71 85 3.1E-13 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CU254_RS02290 f20ca94d22171b7e14882c2f91bb5607 438 Gene3D G3DSA:3.90.226.10 1 219 5.9E-44 T 28-03-2018 CU254_RS22145 f5f64c8c930e2549db9cc653b81215c9 125 SUPERFAMILY SSF46689 44 96 8.51E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS22145 f5f64c8c930e2549db9cc653b81215c9 125 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 60 75 1.1E-7 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CU254_RS22145 f5f64c8c930e2549db9cc653b81215c9 125 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 75 91 1.1E-7 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CU254_RS22145 f5f64c8c930e2549db9cc653b81215c9 125 Gene3D G3DSA:1.10.10.60 3 48 2.1E-16 T 28-03-2018 CU254_RS22145 f5f64c8c930e2549db9cc653b81215c9 125 Gene3D G3DSA:1.10.10.60 49 105 1.6E-18 T 28-03-2018 CU254_RS22145 f5f64c8c930e2549db9cc653b81215c9 125 SMART SM00342 8 91 2.9E-37 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS22145 f5f64c8c930e2549db9cc653b81215c9 125 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 45 87 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CU254_RS22145 f5f64c8c930e2549db9cc653b81215c9 125 SUPERFAMILY SSF46689 2 41 1.2E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS22145 f5f64c8c930e2549db9cc653b81215c9 125 Pfam PF12833 Helix-turn-helix domain 14 93 2.7E-27 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS29370 33af3db6dab59edf69185f0e3dbbf23a 495 Pfam PF00171 Aldehyde dehydrogenase family 18 476 1.0E-138 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CU254_RS29370 33af3db6dab59edf69185f0e3dbbf23a 495 Gene3D G3DSA:3.40.605.10 1 263 1.3E-83 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CU254_RS29370 33af3db6dab59edf69185f0e3dbbf23a 495 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 5 480 2.9E-212 T 28-03-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373|Reactome: R-HSA-70895 CU254_RS29370 33af3db6dab59edf69185f0e3dbbf23a 495 SUPERFAMILY SSF53720 3 481 4.97E-147 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CU254_RS29370 33af3db6dab59edf69185f0e3dbbf23a 495 Gene3D G3DSA:3.40.309.10 264 459 1.7E-64 T 28-03-2018 CU254_RS29370 33af3db6dab59edf69185f0e3dbbf23a 495 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 275 286 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 Gene3D G3DSA:3.10.129.10 3508 3632 1.4E-4 T 28-03-2018 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 Gene3D G3DSA:3.10.129.10 1853 1977 6.8E-7 T 28-03-2018 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 Gene3D G3DSA:3.40.366.10 517 657 6.4E-41 T 28-03-2018 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 Gene3D G3DSA:3.40.366.10 1489 1630 2.1E-43 T 28-03-2018 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 Gene3D G3DSA:3.40.366.10 3146 3281 1.8E-42 T 28-03-2018 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 SUPERFAMILY SSF52151 4870 5033 8.63E-24 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 Gene3D G3DSA:3.40.366.10 3324 3448 3.4E-29 T 28-03-2018 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 SUPERFAMILY SSF51735 2261 2467 6.47E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 SUPERFAMILY SSF52151 1682 1778 2.88E-68 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 SUPERFAMILY SSF52151 1489 1618 2.88E-68 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 ProSitePatterns PS00012 Phosphopantetheine attachment site. 912 927 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 SUPERFAMILY SSF53901 8 362 2.56E-81 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 SUPERFAMILY SSF53901 393 411 2.56E-81 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 Gene3D G3DSA:3.30.70.250 3282 3323 1.5E-17 T 28-03-2018 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 Gene3D G3DSA:3.30.70.250 1631 1674 2.3E-15 T 28-03-2018 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 SUPERFAMILY SSF51735 2077 2252 1.18E-22 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 Gene3D G3DSA:3.40.47.10 1 255 3.4E-74 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 Gene3D G3DSA:3.40.47.10 2625 2893 7.7E-89 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 Gene3D G3DSA:3.40.47.10 969 1233 6.2E-85 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 Gene3D G3DSA:3.40.47.10 4337 4597 2.0E-85 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 SUPERFAMILY SSF53901 4331 4707 3.98E-102 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 SMART SM00825 Beta-ketoacyl synthase 4337 4762 3.6E-224 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 SMART SM00825 Beta-ketoacyl synthase 976 1396 2.0E-218 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 SMART SM00825 Beta-ketoacyl synthase 2633 3056 2.6E-230 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 SMART SM00825 Beta-ketoacyl synthase 11 419 7.5E-175 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4270 4285 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 Gene3D G3DSA:1.10.1200.10 2513 2620 1.4E-18 T 28-03-2018 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 Pfam PF00550 Phosphopantetheine attachment site 4246 4311 1.4E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 Pfam PF00550 Phosphopantetheine attachment site 887 953 2.2E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 Pfam PF00550 Phosphopantetheine attachment site 2543 2608 1.7E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 SUPERFAMILY SSF47336 2539 2646 1.18E-22 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 Gene3D G3DSA:3.40.366.10 4974 5065 5.2E-6 T 28-03-2018 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 Gene3D G3DSA:1.10.1200.10 863 961 9.8E-18 T 28-03-2018 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3007 3119 7.6E-16 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 4712 4821 2.0E-16 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1347 1460 2.3E-17 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 369 483 4.9E-18 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 SUPERFAMILY SSF47336 4239 4350 2.09E-24 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2263 2439 1.3E-58 T 28-03-2018 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3965 4145 7.6E-61 T 28-03-2018 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2889 3004 2.1E-44 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 4593 4709 7.1E-44 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 251 367 1.1E-38 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1229 1344 1.4E-43 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 SUPERFAMILY SSF55048 3271 3332 2.75E-11 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 10 243 9.0E-71 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4336 4585 2.6E-90 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 975 1221 1.7E-88 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2632 2881 8.6E-92 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 Gene3D G3DSA:3.30.70.250 658 701 1.7E-17 T 28-03-2018 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 SUPERFAMILY SSF55048 647 710 9.29E-11 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2794 2810 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 SUPERFAMILY SSF51735 3775 3950 3.5E-31 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 Gene3D G3DSA:3.40.366.10 702 827 1.5E-25 T 28-03-2018 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 Gene3D G3DSA:3.40.366.10 1675 1796 2.8E-26 T 28-03-2018 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 Gene3D G3DSA:3.40.366.10 4862 4973 3.4E-21 T 28-03-2018 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2567 2582 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 4498 4514 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 SMART SM00826 3504 3666 3.0E-70 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 SMART SM00826 1855 2011 9.2E-69 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 SUPERFAMILY SSF52151 712 808 4.19E-64 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 SUPERFAMILY SSF52151 518 648 4.19E-64 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 Pfam PF00698 Acyl transferase domain 1491 1798 1.4E-87 T 28-03-2018 IPR014043 Acyl transferase CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 Pfam PF00698 Acyl transferase domain 519 835 2.5E-53 T 28-03-2018 IPR014043 Acyl transferase CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 Pfam PF00698 Acyl transferase domain 3150 3426 6.9E-53 T 28-03-2018 IPR014043 Acyl transferase CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 SUPERFAMILY SSF52151 3147 3266 8.11E-74 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 SUPERFAMILY SSF52151 3325 3435 8.11E-74 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 SUPERFAMILY SSF53901 972 1343 1.41E-103 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 Pfam PF14765 Polyketide synthase dehydratase 1855 2110 7.7E-48 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 Pfam PF14765 Polyketide synthase dehydratase 3504 3773 1.6E-47 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 Gene3D G3DSA:3.40.50.720 2255 2512 9.1E-49 T 28-03-2018 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 Gene3D G3DSA:3.40.50.720 3958 4208 2.4E-49 T 28-03-2018 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 Gene3D G3DSA:1.10.1200.10 4237 4336 4.5E-21 T 28-03-2018 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 SMART SM00823 Phosphopantetheine attachment site 4243 4315 1.2E-31 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 SMART SM00823 Phosphopantetheine attachment site 885 957 1.3E-21 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 SMART SM00823 Phosphopantetheine attachment site 2540 2612 1.2E-29 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 SUPERFAMILY SSF51735 3963 4173 3.38E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 Pfam PF08659 KR domain 2263 2438 3.8E-55 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 Pfam PF08659 KR domain 3965 4143 3.9E-58 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 3150 3439 1.8E-115 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 520 818 6.0E-111 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1493 1790 3.8E-113 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 SMART SM01294 2542 2608 1.1E-4 T 28-03-2018 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 SMART SM01294 4244 4311 9.4E-6 T 28-03-2018 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 Gene3D G3DSA:3.40.47.10 4600 4760 6.4E-61 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 Gene3D G3DSA:3.40.47.10 258 417 4.6E-56 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 Gene3D G3DSA:3.40.47.10 2896 3054 8.1E-64 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 Gene3D G3DSA:3.40.47.10 1236 1394 7.8E-62 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 SUPERFAMILY SSF53901 2629 3002 3.99E-106 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 SUPERFAMILY SSF47336 881 989 1.31E-20 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 SUPERFAMILY SSF55048 1616 1681 9.29E-11 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CU254_RS05900 1120cb1f0b1205207715fa71544d6bcc 5105 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1134 1150 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CU254_RS07815 2a3aab35e8a283ae3e6c90978ec35380 119 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 1 21 1.1E-8 T 28-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 CU254_RS07815 2a3aab35e8a283ae3e6c90978ec35380 119 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 21 40 1.1E-8 T 28-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 CU254_RS07815 2a3aab35e8a283ae3e6c90978ec35380 119 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 40 58 1.1E-8 T 28-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 CU254_RS07815 2a3aab35e8a283ae3e6c90978ec35380 119 Pfam PF02416 mttA/Hcf106 family 4 37 2.2E-4 T 28-03-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 CU254_RS30705 6de2273c6bad6903b3e634cb4eebe20e 267 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 111 261 2.3E-17 T 28-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 CU254_RS30705 6de2273c6bad6903b3e634cb4eebe20e 267 SUPERFAMILY SSF46689 37 101 1.05E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS30705 6de2273c6bad6903b3e634cb4eebe20e 267 Gene3D G3DSA:1.10.357.10 103 265 7.8E-32 T 28-03-2018 CU254_RS30705 6de2273c6bad6903b3e634cb4eebe20e 267 Gene3D G3DSA:1.10.10.60 10 98 1.5E-16 T 28-03-2018 CU254_RS30705 6de2273c6bad6903b3e634cb4eebe20e 267 SUPERFAMILY SSF48498 113 264 3.78E-23 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS30705 6de2273c6bad6903b3e634cb4eebe20e 267 Pfam PF00440 Bacterial regulatory proteins, tetR family 48 92 1.9E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS00485 be6b14d6c5ab24aebad27ec90656f0f6 247 Gene3D G3DSA:1.10.260.40 29 91 2.2E-5 T 28-03-2018 CU254_RS00485 be6b14d6c5ab24aebad27ec90656f0f6 247 SUPERFAMILY SSF47413 3 54 9.93E-7 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS00485 be6b14d6c5ab24aebad27ec90656f0f6 247 Gene3D G3DSA:1.10.10.60 3 28 6.9E-5 T 28-03-2018 CU254_RS24370 8b82f50cb1d200d3a3469829c279528f 399 Gene3D G3DSA:1.10.10.10 13 78 6.9E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS24370 8b82f50cb1d200d3a3469829c279528f 399 Pfam PF00480 ROK family 89 380 1.2E-42 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CU254_RS24370 8b82f50cb1d200d3a3469829c279528f 399 Gene3D G3DSA:3.30.420.40 79 206 3.9E-25 T 28-03-2018 CU254_RS24370 8b82f50cb1d200d3a3469829c279528f 399 SUPERFAMILY SSF53067 86 387 1.53E-48 T 28-03-2018 CU254_RS24370 8b82f50cb1d200d3a3469829c279528f 399 SUPERFAMILY SSF46785 18 80 1.07E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS24370 8b82f50cb1d200d3a3469829c279528f 399 Gene3D G3DSA:3.30.420.40 207 396 3.7E-49 T 28-03-2018 CU254_RS24370 8b82f50cb1d200d3a3469829c279528f 399 Pfam PF12802 MarR family 19 65 1.3E-6 T 28-03-2018 CU254_RS24455 a0d1728fb61f21dabd68f5983c5616a0 460 ProSitePatterns PS00218 Amino acid permeases signature. 44 74 - T 28-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CU254_RS24455 a0d1728fb61f21dabd68f5983c5616a0 460 PIRSF PIRSF006060 1 457 4.0E-72 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CU254_RS24455 a0d1728fb61f21dabd68f5983c5616a0 460 Pfam PF00324 Amino acid permease 19 445 1.3E-104 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CU254_RS33710 408fe7d52e13fdd01cbecf462a52a0bb 383 Gene3D G3DSA:2.120.10.30 276 376 9.0E-10 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CU254_RS33710 408fe7d52e13fdd01cbecf462a52a0bb 383 Gene3D G3DSA:2.120.10.30 16 275 3.4E-42 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CU254_RS33710 408fe7d52e13fdd01cbecf462a52a0bb 383 Pfam PF07995 Glucose / Sorbosone dehydrogenase 41 372 2.7E-78 T 28-03-2018 IPR012938 Glucose/Sorbosone dehydrogenase CU254_RS33710 408fe7d52e13fdd01cbecf462a52a0bb 383 SUPERFAMILY SSF50952 20 382 2.22E-33 T 28-03-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 CU254_RS14410 afc1246905bdacfba842b0bc9c594e7e 744 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 582 592 1.9E-24 T 28-03-2018 CU254_RS14410 afc1246905bdacfba842b0bc9c594e7e 744 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 635 654 1.9E-24 T 28-03-2018 CU254_RS14410 afc1246905bdacfba842b0bc9c594e7e 744 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 439 453 1.9E-24 T 28-03-2018 CU254_RS14410 afc1246905bdacfba842b0bc9c594e7e 744 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 289 303 1.9E-24 T 28-03-2018 CU254_RS14410 afc1246905bdacfba842b0bc9c594e7e 744 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 560 571 1.9E-24 T 28-03-2018 CU254_RS14410 afc1246905bdacfba842b0bc9c594e7e 744 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 658 670 1.9E-24 T 28-03-2018 CU254_RS14410 afc1246905bdacfba842b0bc9c594e7e 744 SUPERFAMILY SSF81653 245 336 5.75E-20 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CU254_RS14410 afc1246905bdacfba842b0bc9c594e7e 744 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 635 651 1.8E-9 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CU254_RS14410 afc1246905bdacfba842b0bc9c594e7e 744 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 607 623 1.8E-9 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CU254_RS14410 afc1246905bdacfba842b0bc9c594e7e 744 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 666 691 1.8E-9 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CU254_RS14410 afc1246905bdacfba842b0bc9c594e7e 744 Gene3D G3DSA:3.40.1110.10 457 562 5.3E-29 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CU254_RS14410 afc1246905bdacfba842b0bc9c594e7e 744 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 204 738 7.2E-149 T 28-03-2018 CU254_RS14410 afc1246905bdacfba842b0bc9c594e7e 744 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 161 737 7.4E-169 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CU254_RS14410 afc1246905bdacfba842b0bc9c594e7e 744 SUPERFAMILY SSF81665 340 431 1.31E-11 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CU254_RS14410 afc1246905bdacfba842b0bc9c594e7e 744 Gene3D G3DSA:3.40.50.1000 563 699 2.7E-38 T 28-03-2018 IPR023214 HAD-like domain CU254_RS14410 afc1246905bdacfba842b0bc9c594e7e 744 Pfam PF00702 haloacid dehalogenase-like hydrolase 435 649 2.7E-44 T 28-03-2018 CU254_RS14410 afc1246905bdacfba842b0bc9c594e7e 744 SUPERFAMILY SSF55008 12 82 2.36E-19 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CU254_RS14410 afc1246905bdacfba842b0bc9c594e7e 744 Gene3D G3DSA:3.30.70.100 1 77 4.5E-21 T 28-03-2018 CU254_RS14410 afc1246905bdacfba842b0bc9c594e7e 744 ProSitePatterns PS01047 Heavy-metal-associated domain. 20 48 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CU254_RS14410 afc1246905bdacfba842b0bc9c594e7e 744 Pfam PF00403 Heavy-metal-associated domain 18 76 9.4E-14 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CU254_RS14410 afc1246905bdacfba842b0bc9c594e7e 744 Pfam PF00122 E1-E2 ATPase 240 417 1.1E-46 T 28-03-2018 CU254_RS14410 afc1246905bdacfba842b0bc9c594e7e 744 SUPERFAMILY SSF56784 437 457 7.15E-53 T 28-03-2018 IPR023214 HAD-like domain CU254_RS14410 afc1246905bdacfba842b0bc9c594e7e 744 SUPERFAMILY SSF56784 492 735 7.15E-53 T 28-03-2018 IPR023214 HAD-like domain CU254_RS14410 afc1246905bdacfba842b0bc9c594e7e 744 Gene3D G3DSA:1.20.1110.10 78 456 9.0E-37 T 28-03-2018 CU254_RS14410 afc1246905bdacfba842b0bc9c594e7e 744 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 441 447 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CU254_RS14410 afc1246905bdacfba842b0bc9c594e7e 744 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 214 714 2.0E-81 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CU254_RS12430 5cf2964c54f6747914b66535c2549502 129 SUPERFAMILY SSF55961 1 118 3.84E-23 T 28-03-2018 CU254_RS12430 5cf2964c54f6747914b66535c2549502 129 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 1 122 1.0E-16 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase CU254_RS12430 5cf2964c54f6747914b66535c2549502 129 Gene3D G3DSA:3.30.530.20 2 128 2.0E-21 T 28-03-2018 IPR023393 START-like domain CU254_RS18105 f98c481b5f515cec6aab048d88c0b30c 412 SUPERFAMILY SSF52374 30 336 5.9E-68 T 28-03-2018 CU254_RS18105 f98c481b5f515cec6aab048d88c0b30c 412 Gene3D G3DSA:1.20.120.640 330 412 1.0E-15 T 28-03-2018 CU254_RS18105 f98c481b5f515cec6aab048d88c0b30c 412 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 40 51 2.7E-24 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CU254_RS18105 f98c481b5f515cec6aab048d88c0b30c 412 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 213 231 2.7E-24 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CU254_RS18105 f98c481b5f515cec6aab048d88c0b30c 412 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 244 265 2.7E-24 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CU254_RS18105 f98c481b5f515cec6aab048d88c0b30c 412 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 76 85 2.7E-24 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CU254_RS18105 f98c481b5f515cec6aab048d88c0b30c 412 Hamap MF_01697 L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase [mshC]. 9 412 53.699 T 28-03-2018 IPR017812 Mycothiol ligase MshC GO:0010125|GO:0035446 CU254_RS18105 f98c481b5f515cec6aab048d88c0b30c 412 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 38 337 2.2E-82 T 28-03-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 CU254_RS18105 f98c481b5f515cec6aab048d88c0b30c 412 Gene3D G3DSA:3.40.50.620 1 329 8.9E-70 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS18105 f98c481b5f515cec6aab048d88c0b30c 412 TIGRFAM TIGR03447 mycothiol_MshC: cysteine--1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase 2 411 2.5E-214 T 28-03-2018 IPR017812 Mycothiol ligase MshC GO:0010125|GO:0035446 CU254_RS21890 1dac938942a416657c041b850d1cbd44 155 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 32 141 8.5E-23 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CU254_RS21890 1dac938942a416657c041b850d1cbd44 155 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 29 146 18.596 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CU254_RS07015 329c6f44a108c5dfcb59f7ea384b4d4d 220 Gene3D G3DSA:1.10.10.10 1 52 9.8E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS07015 329c6f44a108c5dfcb59f7ea384b4d4d 220 SUPERFAMILY SSF46785 3 59 1.63E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS07015 329c6f44a108c5dfcb59f7ea384b4d4d 220 Gene3D G3DSA:3.30.450.40 54 220 7.8E-38 T 28-03-2018 IPR029016 GAF domain-like CU254_RS07015 329c6f44a108c5dfcb59f7ea384b4d4d 220 Pfam PF09339 IclR helix-turn-helix domain 2 43 9.6E-10 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS07015 329c6f44a108c5dfcb59f7ea384b4d4d 220 Pfam PF01614 Bacterial transcriptional regulator 111 217 4.1E-17 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal CU254_RS07015 329c6f44a108c5dfcb59f7ea384b4d4d 220 SMART SM00346 1 79 1.4E-15 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS07015 329c6f44a108c5dfcb59f7ea384b4d4d 220 SUPERFAMILY SSF55781 49 220 1.05E-37 T 28-03-2018 IPR029016 GAF domain-like CU254_RS09720 9b59194669c18836a48cd4b6f1604512 275 Pfam PF01678 Diaminopimelate epimerase 147 259 2.8E-19 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CU254_RS09720 9b59194669c18836a48cd4b6f1604512 275 Pfam PF01678 Diaminopimelate epimerase 6 129 1.8E-36 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CU254_RS09720 9b59194669c18836a48cd4b6f1604512 275 SUPERFAMILY SSF54506 136 265 2.55E-31 T 28-03-2018 CU254_RS09720 9b59194669c18836a48cd4b6f1604512 275 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 4 265 1.3E-68 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CU254_RS09720 9b59194669c18836a48cd4b6f1604512 275 Gene3D G3DSA:3.10.310.10 1 132 1.6E-49 T 28-03-2018 CU254_RS09720 9b59194669c18836a48cd4b6f1604512 275 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 71 85 - T 28-03-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CU254_RS09720 9b59194669c18836a48cd4b6f1604512 275 SUPERFAMILY SSF54506 4 131 2.17E-35 T 28-03-2018 CU254_RS09720 9b59194669c18836a48cd4b6f1604512 275 Gene3D G3DSA:3.10.310.10 133 254 2.7E-39 T 28-03-2018 CU254_RS09720 9b59194669c18836a48cd4b6f1604512 275 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 4 267 30.045 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CU254_RS28765 ec2106a1595b0d3e6334698f9a60010f 540 Gene3D G3DSA:2.60.40.10 197 295 5.7E-4 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS28765 ec2106a1595b0d3e6334698f9a60010f 540 Gene3D G3DSA:2.60.40.10 303 380 0.0068 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS28125 1dbbf6ef9ff880975cae852ccde387d7 257 Pfam PF07848 PaaX-like protein 1 64 1.1E-14 T 28-03-2018 IPR012906 PaaX-like, N-terminal CU254_RS28125 1dbbf6ef9ff880975cae852ccde387d7 257 Gene3D G3DSA:1.10.10.10 1 78 3.3E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS28125 1dbbf6ef9ff880975cae852ccde387d7 257 PIRSF PIRSF020623 1 257 3.2E-57 T 28-03-2018 IPR011965 Phenylacetic acid degradation operon negative regulatory protein PaaX GO:0006351 CU254_RS28125 1dbbf6ef9ff880975cae852ccde387d7 257 Pfam PF08223 PaaX-like protein C-terminal domain 162 251 3.7E-18 T 28-03-2018 IPR013225 PaaX-like, C-terminal CU254_RS28125 1dbbf6ef9ff880975cae852ccde387d7 257 SUPERFAMILY SSF46785 24 76 1.82E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS00835 fa57a6677f255ecc8e40acfe0e07db1a 177 Gene3D G3DSA:1.10.1780.10 70 177 1.8E-24 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CU254_RS00835 fa57a6677f255ecc8e40acfe0e07db1a 177 Gene3D G3DSA:1.10.1780.10 1 69 3.7E-11 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CU254_RS00835 fa57a6677f255ecc8e40acfe0e07db1a 177 SUPERFAMILY SSF81923 3 69 6.54E-8 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CU254_RS00835 fa57a6677f255ecc8e40acfe0e07db1a 177 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 130 175 2.9E-11 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CU254_RS00835 fa57a6677f255ecc8e40acfe0e07db1a 177 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 77 96 2.0 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CU254_RS00835 fa57a6677f255ecc8e40acfe0e07db1a 177 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 16 67 2.8E-5 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CU254_RS00835 fa57a6677f255ecc8e40acfe0e07db1a 177 SUPERFAMILY SSF81923 78 174 2.65E-13 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CU254_RS01655 58401b52a4d8fd0ef021436e8de2949e 801 SMART SM00382 358 511 7.2E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS01655 58401b52a4d8fd0ef021436e8de2949e 801 Hamap MF_01973 Lon protease [lon]. 7 791 58.577 T 28-03-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 CU254_RS01655 58401b52a4d8fd0ef021436e8de2949e 801 SUPERFAMILY SSF88697 7 201 1.27E-20 T 28-03-2018 IPR015947 PUA-like domain CU254_RS01655 58401b52a4d8fd0ef021436e8de2949e 801 SUPERFAMILY SSF52540 308 566 2.25E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS01655 58401b52a4d8fd0ef021436e8de2949e 801 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 581 791 2.1E-78 T 28-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 CU254_RS01655 58401b52a4d8fd0ef021436e8de2949e 801 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 695 703 - T 28-03-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 CU254_RS01655 58401b52a4d8fd0ef021436e8de2949e 801 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 363 498 5.5E-20 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CU254_RS01655 58401b52a4d8fd0ef021436e8de2949e 801 SMART SM00464 6 204 1.3E-21 T 28-03-2018 IPR003111 Lon, substrate-binding domain CU254_RS01655 58401b52a4d8fd0ef021436e8de2949e 801 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 722 741 3.2E-51 T 28-03-2018 CU254_RS01655 58401b52a4d8fd0ef021436e8de2949e 801 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 611 627 3.2E-51 T 28-03-2018 CU254_RS01655 58401b52a4d8fd0ef021436e8de2949e 801 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 745 763 3.2E-51 T 28-03-2018 CU254_RS01655 58401b52a4d8fd0ef021436e8de2949e 801 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 692 711 3.2E-51 T 28-03-2018 CU254_RS01655 58401b52a4d8fd0ef021436e8de2949e 801 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 366 385 3.2E-51 T 28-03-2018 CU254_RS01655 58401b52a4d8fd0ef021436e8de2949e 801 Gene3D G3DSA:1.10.8.60 502 595 6.1E-26 T 28-03-2018 CU254_RS01655 58401b52a4d8fd0ef021436e8de2949e 801 Gene3D G3DSA:1.10.4060.10 121 212 4.8E-6 T 28-03-2018 CU254_RS01655 58401b52a4d8fd0ef021436e8de2949e 801 PIRSF PIRSF001174 2 793 2.7E-253 T 28-03-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 CU254_RS01655 58401b52a4d8fd0ef021436e8de2949e 801 Gene3D G3DSA:3.40.50.300 314 501 1.0E-29 T 28-03-2018 CU254_RS01655 58401b52a4d8fd0ef021436e8de2949e 801 TIGRFAM TIGR00763 lon: endopeptidase La 8 790 4.8E-247 T 28-03-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 CU254_RS01655 58401b52a4d8fd0ef021436e8de2949e 801 Gene3D G3DSA:2.30.130.40 1 114 1.5E-14 T 28-03-2018 CU254_RS01655 58401b52a4d8fd0ef021436e8de2949e 801 SUPERFAMILY SSF54211 611 789 1.1E-52 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CU254_RS01655 58401b52a4d8fd0ef021436e8de2949e 801 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 7 201 2.8E-22 T 28-03-2018 IPR003111 Lon, substrate-binding domain CU254_RS01655 58401b52a4d8fd0ef021436e8de2949e 801 Gene3D G3DSA:3.30.230.10 602 791 6.2E-61 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CU254_RS37420 11daea47323ee9ed3d4517dcf4157f61 461 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 185 351 3.5E-50 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CU254_RS37420 11daea47323ee9ed3d4517dcf4157f61 461 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 186 351 3.8E-45 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CU254_RS39420 2b14db8f35933ff338a872badbd1c7f9 317 SUPERFAMILY SSF63817 100 202 1.07E-20 T 28-03-2018 IPR023365 Sortase domain CU254_RS39420 2b14db8f35933ff338a872badbd1c7f9 317 Gene3D G3DSA:2.40.260.10 22 309 1.1E-38 T 28-03-2018 IPR023365 Sortase domain CU254_RS39420 2b14db8f35933ff338a872badbd1c7f9 317 Pfam PF04203 Sortase family 120 294 8.2E-27 T 28-03-2018 IPR005754 Sortase family CU254_RS20000 ab6cfcc1fedd6212c9156c04df01e412 447 Gene3D G3DSA:1.20.1250.20 232 445 6.1E-26 T 28-03-2018 CU254_RS20000 ab6cfcc1fedd6212c9156c04df01e412 447 Gene3D G3DSA:1.20.1250.20 21 231 1.3E-24 T 28-03-2018 CU254_RS20000 ab6cfcc1fedd6212c9156c04df01e412 447 ProSitePatterns PS00217 Sugar transport proteins signature 2. 135 160 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CU254_RS20000 ab6cfcc1fedd6212c9156c04df01e412 447 SUPERFAMILY SSF103473 23 441 3.27E-68 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS20000 ab6cfcc1fedd6212c9156c04df01e412 447 Pfam PF07690 Major Facilitator Superfamily 31 275 8.1E-22 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS06750 0099317d6fa977f03081a9d03010bb4d 364 SUPERFAMILY SSF52402 1 243 7.5E-48 T 28-03-2018 CU254_RS06750 0099317d6fa977f03081a9d03010bb4d 364 Gene3D G3DSA:2.30.30.280 212 276 8.1E-15 T 28-03-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 Reactome: R-HSA-6787450 CU254_RS06750 0099317d6fa977f03081a9d03010bb4d 364 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 1 361 36.564 T 28-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 CU254_RS06750 0099317d6fa977f03081a9d03010bb4d 364 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 1 360 2.2E-89 T 28-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 CU254_RS06750 0099317d6fa977f03081a9d03010bb4d 364 Gene3D G3DSA:3.40.50.620 1 210 8.1E-57 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS06750 0099317d6fa977f03081a9d03010bb4d 364 Pfam PF03054 tRNA methyl transferase 1 360 3.6E-116 T 28-03-2018 CU254_RS06750 0099317d6fa977f03081a9d03010bb4d 364 Gene3D G3DSA:2.40.30.10 277 364 1.2E-17 T 28-03-2018 CU254_RS25845 1f80ecaeff0c1d9f143b58407680abc6 247 Gene3D G3DSA:2.40.10.10 39 74 3.4E-7 T 28-03-2018 CU254_RS25845 1f80ecaeff0c1d9f143b58407680abc6 247 SMART SM00020 38 241 5.0E-8 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CU254_RS25845 1f80ecaeff0c1d9f143b58407680abc6 247 Pfam PF00089 Trypsin 41 235 1.1E-22 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CU254_RS25845 1f80ecaeff0c1d9f143b58407680abc6 247 Gene3D G3DSA:2.40.10.10 75 246 6.2E-25 T 28-03-2018 CU254_RS25845 1f80ecaeff0c1d9f143b58407680abc6 247 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 200 211 - T 28-03-2018 IPR033116 Serine proteases, trypsin family, serine active site CU254_RS25845 1f80ecaeff0c1d9f143b58407680abc6 247 SUPERFAMILY SSF50494 37 245 8.61E-31 T 28-03-2018 IPR009003 Peptidase S1, PA clan CU254_RS25845 1f80ecaeff0c1d9f143b58407680abc6 247 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 66 81 1.2E-7 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CU254_RS25845 1f80ecaeff0c1d9f143b58407680abc6 247 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 116 130 1.2E-7 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CU254_RS25845 1f80ecaeff0c1d9f143b58407680abc6 247 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 199 211 1.2E-7 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CU254_RS35405 5e8ce35200115d3f24c1a0b2d4a97fd6 397 SUPERFAMILY SSF63882 2 170 9.03E-53 T 28-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CU254_RS35405 5e8ce35200115d3f24c1a0b2d4a97fd6 397 Gene3D G3DSA:3.40.980.10 145 318 2.0E-49 T 28-03-2018 IPR001453 MoaB/Mog domain CU254_RS35405 5e8ce35200115d3f24c1a0b2d4a97fd6 397 SUPERFAMILY SSF53218 173 315 1.83E-37 T 28-03-2018 IPR001453 MoaB/Mog domain CU254_RS35405 5e8ce35200115d3f24c1a0b2d4a97fd6 397 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 172 307 1.3E-32 T 28-03-2018 IPR001453 MoaB/Mog domain CU254_RS35405 5e8ce35200115d3f24c1a0b2d4a97fd6 397 Gene3D G3DSA:2.170.190.11 55 136 7.4E-32 T 28-03-2018 CU254_RS35405 5e8ce35200115d3f24c1a0b2d4a97fd6 397 Pfam PF03453 MoeA N-terminal region (domain I and II) 2 162 3.5E-45 T 28-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CU254_RS35405 5e8ce35200115d3f24c1a0b2d4a97fd6 397 SUPERFAMILY SSF63867 321 397 6.67E-17 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CU254_RS35405 5e8ce35200115d3f24c1a0b2d4a97fd6 397 Pfam PF00994 Probable molybdopterin binding domain 176 309 8.7E-24 T 28-03-2018 IPR001453 MoaB/Mog domain CU254_RS35405 5e8ce35200115d3f24c1a0b2d4a97fd6 397 Gene3D G3DSA:3.90.105.10 22 54 6.3E-12 T 28-03-2018 CU254_RS35405 5e8ce35200115d3f24c1a0b2d4a97fd6 397 Gene3D G3DSA:2.40.340.10 323 397 3.1E-21 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CU254_RS35405 5e8ce35200115d3f24c1a0b2d4a97fd6 397 SMART SM00852 175 311 4.3E-35 T 28-03-2018 IPR001453 MoaB/Mog domain CU254_RS35405 5e8ce35200115d3f24c1a0b2d4a97fd6 397 Pfam PF03454 MoeA C-terminal region (domain IV) 324 397 5.2E-16 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CU254_RS28560 491c055b9ae73896034942699f8a01e8 372 SUPERFAMILY SSF55124 175 289 4.09E-14 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CU254_RS28560 491c055b9ae73896034942699f8a01e8 372 Gene3D G3DSA:3.30.413.10 292 356 4.1E-9 T 28-03-2018 CU254_RS28560 491c055b9ae73896034942699f8a01e8 372 SUPERFAMILY SSF56014 296 348 4.84E-5 T 28-03-2018 CU254_RS28560 491c055b9ae73896034942699f8a01e8 372 SUPERFAMILY SSF55124 6 83 5.23E-19 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CU254_RS28560 491c055b9ae73896034942699f8a01e8 372 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 27 70 3.4E-12 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CU254_RS28560 491c055b9ae73896034942699f8a01e8 372 SUPERFAMILY SSF56014 92 197 9.81E-5 T 28-03-2018 CU254_RS28560 491c055b9ae73896034942699f8a01e8 372 Gene3D G3DSA:3.90.480.10 22 291 1.3E-36 T 28-03-2018 CU254_RS26825 34f41510227655c9f108b114823be7ac 368 SMART SM00359 280 358 6.5E-19 T 28-03-2018 IPR002478 PUA domain GO:0003723 CU254_RS26825 34f41510227655c9f108b114823be7ac 368 PRINTS PR00474 Glutamate 5-kinase family signature 123 144 1.2E-50 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CU254_RS26825 34f41510227655c9f108b114823be7ac 368 PRINTS PR00474 Glutamate 5-kinase family signature 155 182 1.2E-50 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CU254_RS26825 34f41510227655c9f108b114823be7ac 368 PRINTS PR00474 Glutamate 5-kinase family signature 49 63 1.2E-50 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CU254_RS26825 34f41510227655c9f108b114823be7ac 368 PRINTS PR00474 Glutamate 5-kinase family signature 215 235 1.2E-50 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CU254_RS26825 34f41510227655c9f108b114823be7ac 368 PRINTS PR00474 Glutamate 5-kinase family signature 83 111 1.2E-50 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CU254_RS26825 34f41510227655c9f108b114823be7ac 368 Hamap MF_00456 Glutamate 5-kinase [proB]. 12 262 34.47 T 28-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CU254_RS26825 34f41510227655c9f108b114823be7ac 368 TIGRFAM TIGR01027 proB: glutamate 5-kinase 12 364 3.6E-115 T 28-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CU254_RS26825 34f41510227655c9f108b114823be7ac 368 ProSitePatterns PS00902 Glutamate 5-kinase signature. 213 230 - T 28-03-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CU254_RS26825 34f41510227655c9f108b114823be7ac 368 Pfam PF00696 Amino acid kinase family 13 239 6.8E-42 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CU254_RS26825 34f41510227655c9f108b114823be7ac 368 SUPERFAMILY SSF53633 12 259 1.26E-58 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CU254_RS26825 34f41510227655c9f108b114823be7ac 368 SUPERFAMILY SSF88697 280 364 1.16E-17 T 28-03-2018 IPR015947 PUA-like domain CU254_RS26825 34f41510227655c9f108b114823be7ac 368 Pfam PF01472 PUA domain 280 349 1.5E-16 T 28-03-2018 IPR002478 PUA domain GO:0003723 CU254_RS26825 34f41510227655c9f108b114823be7ac 368 PIRSF PIRSF000729 7 366 1.5E-113 T 28-03-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 CU254_RS26825 34f41510227655c9f108b114823be7ac 368 Gene3D G3DSA:2.30.130.10 278 365 2.1E-18 T 28-03-2018 IPR002478 PUA domain GO:0003723 CU254_RS26825 34f41510227655c9f108b114823be7ac 368 Gene3D G3DSA:3.40.1160.10 1 268 5.1E-60 T 28-03-2018 CU254_RS37870 1c066910d90767cfaef41c0bc066c5fe 381 Gene3D G3DSA:1.10.287.1060 22 113 1.1E-13 T 28-03-2018 CU254_RS37870 1c066910d90767cfaef41c0bc066c5fe 381 Gene3D G3DSA:1.10.530.10 256 380 2.5E-18 T 28-03-2018 CU254_RS37870 1c066910d90767cfaef41c0bc066c5fe 381 Pfam PF06013 Proteins of 100 residues with WXG 22 99 7.1E-11 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CU254_RS37870 1c066910d90767cfaef41c0bc066c5fe 381 SUPERFAMILY SSF53955 266 368 1.04E-16 T 28-03-2018 IPR023346 Lysozyme-like domain CU254_RS37870 1c066910d90767cfaef41c0bc066c5fe 381 Pfam PF01464 Transglycosylase SLT domain 291 365 6.3E-14 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 CU254_RS37870 1c066910d90767cfaef41c0bc066c5fe 381 SUPERFAMILY SSF140453 22 113 2.09E-10 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CU254_RS34465 39b27c4505d42f9e9d7571a4096574d3 403 TIGRFAM TIGR02679 TIGR02679: TIGR02679 family protein 25 392 2.1E-100 T 28-03-2018 IPR013495 Conserved hypothetical protein CHP02679 CU254_RS34465 39b27c4505d42f9e9d7571a4096574d3 403 Pfam PF11796 Protein of unknown function N-terminus (DUF3323) 26 226 1.4E-49 T 28-03-2018 IPR024466 Conserved hypothetical protein CHP02679, N terminus CU254_RS34465 39b27c4505d42f9e9d7571a4096574d3 403 Pfam PF09664 Protein of unknown function C-terminus (DUF2399) 248 393 1.3E-46 T 28-03-2018 IPR024465 Domain of unknown function DUF2399 CU254_RS34465 39b27c4505d42f9e9d7571a4096574d3 403 Gene3D G3DSA:3.40.1360.10 231 381 1.8E-9 T 28-03-2018 CU254_RS10420 11088e49fb43b5b699080855aee4c44b 155 Gene3D G3DSA:2.40.30.30 10 141 1.4E-30 T 28-03-2018 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 Reactome: R-HSA-196843 CU254_RS10420 11088e49fb43b5b699080855aee4c44b 155 Pfam PF01687 Riboflavin kinase 10 130 6.8E-28 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CU254_RS10420 11088e49fb43b5b699080855aee4c44b 155 SMART SM00904 7 132 2.7E-31 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CU254_RS10420 11088e49fb43b5b699080855aee4c44b 155 SUPERFAMILY SSF82114 8 135 6.98E-34 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CU254_RS26930 ce6b1b7d0daea9cffe00695b6b05c3fb 875 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 808 872 1.3E-16 T 28-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 CU254_RS26930 ce6b1b7d0daea9cffe00695b6b05c3fb 875 Gene3D G3DSA:1.10.730.10 525 747 1.1E-71 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CU254_RS26930 ce6b1b7d0daea9cffe00695b6b05c3fb 875 Gene3D G3DSA:3.40.50.620 437 524 7.2E-30 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS26930 ce6b1b7d0daea9cffe00695b6b05c3fb 875 PRINTS PR00986 Valyl-tRNA synthetase signature 478 496 3.0E-37 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CU254_RS26930 ce6b1b7d0daea9cffe00695b6b05c3fb 875 PRINTS PR00986 Valyl-tRNA synthetase signature 447 468 3.0E-37 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CU254_RS26930 ce6b1b7d0daea9cffe00695b6b05c3fb 875 PRINTS PR00986 Valyl-tRNA synthetase signature 238 255 3.0E-37 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CU254_RS26930 ce6b1b7d0daea9cffe00695b6b05c3fb 875 PRINTS PR00986 Valyl-tRNA synthetase signature 46 57 3.0E-37 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CU254_RS26930 ce6b1b7d0daea9cffe00695b6b05c3fb 875 PRINTS PR00986 Valyl-tRNA synthetase signature 353 366 3.0E-37 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CU254_RS26930 ce6b1b7d0daea9cffe00695b6b05c3fb 875 Gene3D G3DSA:1.10.287.380 801 871 1.4E-19 T 28-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 CU254_RS26930 ce6b1b7d0daea9cffe00695b6b05c3fb 875 Pfam PF08264 Anticodon-binding domain of tRNA 609 752 3.8E-41 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CU254_RS26930 ce6b1b7d0daea9cffe00695b6b05c3fb 875 Gene3D G3DSA:3.90.740.10 244 436 2.1E-58 T 28-03-2018 CU254_RS26930 ce6b1b7d0daea9cffe00695b6b05c3fb 875 SUPERFAMILY SSF47323 578 821 1.12E-56 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CU254_RS26930 ce6b1b7d0daea9cffe00695b6b05c3fb 875 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 53 64 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CU254_RS26930 ce6b1b7d0daea9cffe00695b6b05c3fb 875 SUPERFAMILY SSF50677 203 341 1.57E-52 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CU254_RS26930 ce6b1b7d0daea9cffe00695b6b05c3fb 875 Hamap MF_02004 Valine--tRNA ligase [valS]. 12 873 15.102 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CU254_RS26930 ce6b1b7d0daea9cffe00695b6b05c3fb 875 Gene3D G3DSA:3.90.740.10 195 243 3.9E-13 T 28-03-2018 CU254_RS26930 ce6b1b7d0daea9cffe00695b6b05c3fb 875 Gene3D G3DSA:3.40.50.620 33 194 3.1E-46 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS26930 ce6b1b7d0daea9cffe00695b6b05c3fb 875 SUPERFAMILY SSF46589 808 872 6.28E-14 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 CU254_RS26930 ce6b1b7d0daea9cffe00695b6b05c3fb 875 SUPERFAMILY SSF52374 348 577 3.75E-137 T 28-03-2018 CU254_RS26930 ce6b1b7d0daea9cffe00695b6b05c3fb 875 SUPERFAMILY SSF52374 9 202 3.75E-137 T 28-03-2018 CU254_RS26930 ce6b1b7d0daea9cffe00695b6b05c3fb 875 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 25 566 8.0E-194 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CU254_RS26930 ce6b1b7d0daea9cffe00695b6b05c3fb 875 TIGRFAM TIGR00422 valS: valine--tRNA ligase 14 853 0.0 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CU254_RS11305 ba163eac8a20f6274457f74277cb9a83 283 Gene3D G3DSA:3.40.50.720 1 158 6.5E-30 T 28-03-2018 CU254_RS11305 ba163eac8a20f6274457f74277cb9a83 283 PIRSF PIRSF000103 1 283 3.0E-78 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CU254_RS11305 ba163eac8a20f6274457f74277cb9a83 283 SUPERFAMILY SSF51735 3 157 4.2E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS11305 ba163eac8a20f6274457f74277cb9a83 283 Gene3D G3DSA:1.10.1040.10 159 283 1.9E-21 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CU254_RS11305 ba163eac8a20f6274457f74277cb9a83 283 SUPERFAMILY SSF48179 159 278 5.44E-25 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CU254_RS11305 ba163eac8a20f6274457f74277cb9a83 283 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 4 157 1.2E-35 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CU254_RS11305 ba163eac8a20f6274457f74277cb9a83 283 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 161 278 1.8E-13 T 28-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CU254_RS33545 bae698cfda11b89e8926ba8b370227e1 317 SUPERFAMILY SSF53067 3 127 9.39E-35 T 28-03-2018 CU254_RS33545 bae698cfda11b89e8926ba8b370227e1 317 Gene3D G3DSA:3.30.420.40 1 121 1.3E-49 T 28-03-2018 CU254_RS33545 bae698cfda11b89e8926ba8b370227e1 317 SUPERFAMILY SSF53067 133 316 3.3E-36 T 28-03-2018 CU254_RS33545 bae698cfda11b89e8926ba8b370227e1 317 Pfam PF02541 Ppx/GppA phosphatase family 28 315 1.6E-70 T 28-03-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 CU254_RS33545 bae698cfda11b89e8926ba8b370227e1 317 Gene3D G3DSA:3.30.420.150 122 316 1.2E-50 T 28-03-2018 CU254_RS03175 478924270e8d402d2acfb93917702c9c 247 SUPERFAMILY SSF54593 2 112 7.65E-22 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS03175 478924270e8d402d2acfb93917702c9c 247 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 2 104 8.7E-8 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CU254_RS03175 478924270e8d402d2acfb93917702c9c 247 Gene3D G3DSA:3.10.180.10 1 117 1.6E-21 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS03175 478924270e8d402d2acfb93917702c9c 247 Gene3D G3DSA:3.10.180.10 129 245 1.6E-15 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS03175 478924270e8d402d2acfb93917702c9c 247 SUPERFAMILY SSF54593 128 237 1.17E-17 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS06245 7e1cd2d8474dae047cb7328cc280cc30 314 SMART SM00342 225 308 4.3E-27 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS06245 7e1cd2d8474dae047cb7328cc280cc30 314 SUPERFAMILY SSF46689 262 312 1.61E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS06245 7e1cd2d8474dae047cb7328cc280cc30 314 SUPERFAMILY SSF46689 211 259 1.79E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS06245 7e1cd2d8474dae047cb7328cc280cc30 314 Pfam PF12833 Helix-turn-helix domain 231 309 1.6E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS06245 7e1cd2d8474dae047cb7328cc280cc30 314 Gene3D G3DSA:3.40.50.880 1 227 7.4E-52 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS06245 7e1cd2d8474dae047cb7328cc280cc30 314 Gene3D G3DSA:1.10.10.60 228 263 2.2E-10 T 28-03-2018 CU254_RS06245 7e1cd2d8474dae047cb7328cc280cc30 314 Pfam PF01965 DJ-1/PfpI family 66 171 2.8E-14 T 28-03-2018 IPR002818 DJ-1/PfpI CU254_RS06245 7e1cd2d8474dae047cb7328cc280cc30 314 Gene3D G3DSA:1.10.10.60 264 314 7.0E-17 T 28-03-2018 CU254_RS06245 7e1cd2d8474dae047cb7328cc280cc30 314 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 262 304 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CU254_RS06245 7e1cd2d8474dae047cb7328cc280cc30 314 SUPERFAMILY SSF52317 1 192 1.62E-41 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS12745 e948084e5424ca26cab4b78676f58587 197 Pfam PF14525 AraC-binding-like domain 29 192 8.2E-24 T 28-03-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like CU254_RS31300 1b85114c77724b6374e737d4468085a9 385 Pfam PF00953 Glycosyl transferase family 4 90 257 7.0E-35 T 28-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CU254_RS24305 3964068f99a0f30a3e0ca5b7ffa77c68 168 Gene3D G3DSA:1.20.120.450 1 168 8.5E-39 T 28-03-2018 CU254_RS24305 3964068f99a0f30a3e0ca5b7ffa77c68 168 SUPERFAMILY SSF109854 4 166 1.27E-35 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CU254_RS24305 3964068f99a0f30a3e0ca5b7ffa77c68 168 Pfam PF04978 Protein of unknown function (DUF664) 10 165 7.8E-22 T 28-03-2018 IPR007061 Protein of unknown function DUF664 CU254_RS03980 7408b400db0373c205417f836624c118 222 SUPERFAMILY SSF53474 1 219 1.14E-33 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS03980 7408b400db0373c205417f836624c118 222 Gene3D G3DSA:3.40.50.1820 1 221 1.1E-30 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS03980 7408b400db0373c205417f836624c118 222 Pfam PF12697 Alpha/beta hydrolase family 2 217 2.7E-9 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS32200 051f4ce0f4fa3d62bbe7d5a4c39125f6 1251 Pfam PF00005 ABC transporter 370 519 4.9E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS32200 051f4ce0f4fa3d62bbe7d5a4c39125f6 1251 Pfam PF00005 ABC transporter 1032 1181 1.6E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS32200 051f4ce0f4fa3d62bbe7d5a4c39125f6 1251 SUPERFAMILY SSF52540 1007 1249 6.66E-84 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS32200 051f4ce0f4fa3d62bbe7d5a4c39125f6 1251 SUPERFAMILY SSF90123 26 342 8.89E-68 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CU254_RS32200 051f4ce0f4fa3d62bbe7d5a4c39125f6 1251 Gene3D G3DSA:1.20.1560.10 23 343 2.1E-57 T 28-03-2018 CU254_RS32200 051f4ce0f4fa3d62bbe7d5a4c39125f6 1251 Gene3D G3DSA:3.40.50.300 1004 1250 2.7E-70 T 28-03-2018 CU254_RS32200 051f4ce0f4fa3d62bbe7d5a4c39125f6 1251 Gene3D G3DSA:3.40.50.300 344 592 6.0E-67 T 28-03-2018 CU254_RS32200 051f4ce0f4fa3d62bbe7d5a4c39125f6 1251 ProSitePatterns PS00211 ABC transporters family signature. 491 505 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS32200 051f4ce0f4fa3d62bbe7d5a4c39125f6 1251 SUPERFAMILY SSF90123 685 999 6.02E-71 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CU254_RS32200 051f4ce0f4fa3d62bbe7d5a4c39125f6 1251 SMART SM00382 379 591 1.7E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS32200 051f4ce0f4fa3d62bbe7d5a4c39125f6 1251 SMART SM00382 1041 1227 5.6E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS32200 051f4ce0f4fa3d62bbe7d5a4c39125f6 1251 Pfam PF00664 ABC transporter transmembrane region 701 967 6.4E-34 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CU254_RS32200 051f4ce0f4fa3d62bbe7d5a4c39125f6 1251 Pfam PF00664 ABC transporter transmembrane region 40 307 3.2E-37 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CU254_RS32200 051f4ce0f4fa3d62bbe7d5a4c39125f6 1251 SUPERFAMILY SSF52540 343 586 4.76E-84 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS32200 051f4ce0f4fa3d62bbe7d5a4c39125f6 1251 Gene3D G3DSA:1.20.1560.10 680 1000 5.1E-58 T 28-03-2018 CU254_RS18475 202483427f42e1eb7a9b6d4d5f741f29 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 182 1.6E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18475 202483427f42e1eb7a9b6d4d5f741f29 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 163 1.6E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18475 202483427f42e1eb7a9b6d4d5f741f29 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 1.6E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18475 202483427f42e1eb7a9b6d4d5f741f29 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 69 80 1.6E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18475 202483427f42e1eb7a9b6d4d5f741f29 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 201 221 1.6E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18475 202483427f42e1eb7a9b6d4d5f741f29 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 118 134 1.6E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18475 202483427f42e1eb7a9b6d4d5f741f29 240 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 175 0.0039 T 28-03-2018 CU254_RS18475 202483427f42e1eb7a9b6d4d5f741f29 240 SUPERFAMILY SSF51735 5 239 9.43E-75 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS18475 202483427f42e1eb7a9b6d4d5f741f29 240 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 236 3.1E-59 T 28-03-2018 CU254_RS18475 202483427f42e1eb7a9b6d4d5f741f29 240 Gene3D G3DSA:3.40.50.720 4 240 1.4E-72 T 28-03-2018 CU254_RS18475 202483427f42e1eb7a9b6d4d5f741f29 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 69 80 6.0E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18475 202483427f42e1eb7a9b6d4d5f741f29 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 163 6.0E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18475 202483427f42e1eb7a9b6d4d5f741f29 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 124 132 6.0E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS01350 2927971c20a73b71bc17024879d05bbd 253 SUPERFAMILY SSF143243 95 249 1.83E-49 T 28-03-2018 CU254_RS01350 2927971c20a73b71bc17024879d05bbd 253 Hamap MF_01357 NAD(P)H-quinone oxidoreductase subunit J, chloroplastic [ndhJ]. 85 241 29.264 T 28-03-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS01350 2927971c20a73b71bc17024879d05bbd 253 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 161 216 5.0E-17 T 28-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS01350 2927971c20a73b71bc17024879d05bbd 253 TIGRFAM TIGR01961 NuoC_fam: NADH (or F420H2) dehydrogenase, subunit C 110 232 4.8E-43 T 28-03-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS01350 2927971c20a73b71bc17024879d05bbd 253 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 112 233 6.6E-44 T 28-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS11415 07a242f30c20346bf90eccfe3df2b012 395 ProSitePatterns PS00787 Chorismate synthase signature 1. 8 23 - T 28-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CU254_RS11415 07a242f30c20346bf90eccfe3df2b012 395 PIRSF PIRSF001456 1 388 5.4E-124 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CU254_RS11415 07a242f30c20346bf90eccfe3df2b012 395 ProSitePatterns PS00789 Chorismate synthase signature 3. 343 359 - T 28-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CU254_RS11415 07a242f30c20346bf90eccfe3df2b012 395 ProSitePatterns PS00788 Chorismate synthase signature 2. 134 150 - T 28-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CU254_RS11415 07a242f30c20346bf90eccfe3df2b012 395 Hamap MF_00300 Chorismate synthase [aroC]. 2 376 34.427 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CU254_RS11415 07a242f30c20346bf90eccfe3df2b012 395 TIGRFAM TIGR00033 aroC: chorismate synthase 2 374 8.3E-122 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CU254_RS11415 07a242f30c20346bf90eccfe3df2b012 395 Pfam PF01264 Chorismate synthase 2 369 4.9E-114 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CU254_RS11415 07a242f30c20346bf90eccfe3df2b012 395 Gene3D G3DSA:3.60.150.10 1 395 4.1E-136 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CU254_RS11415 07a242f30c20346bf90eccfe3df2b012 395 SUPERFAMILY SSF103263 2 392 5.49E-133 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CU254_RS03580 f0d51ef256f747e0b33c2d8e555e5fa7 175 Pfam PF00293 NUDIX domain 47 166 7.7E-12 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CU254_RS03580 f0d51ef256f747e0b33c2d8e555e5fa7 175 SUPERFAMILY SSF55811 47 162 2.57E-20 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CU254_RS03580 f0d51ef256f747e0b33c2d8e555e5fa7 175 Gene3D G3DSA:3.90.79.10 33 175 3.3E-22 T 28-03-2018 CU254_RS21745 342ac5f5ab1b1ae95467d01e339832ab 2119 SMART SM00825 Beta-ketoacyl synthase 24 448 2.1E-198 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CU254_RS21745 342ac5f5ab1b1ae95467d01e339832ab 2119 Gene3D G3DSA:3.10.129.10 910 1026 6.5E-6 T 28-03-2018 CU254_RS21745 342ac5f5ab1b1ae95467d01e339832ab 2119 SUPERFAMILY SSF51735 1194 1387 5.51E-20 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS21745 342ac5f5ab1b1ae95467d01e339832ab 2119 Pfam PF14765 Polyketide synthase dehydratase 904 1189 2.9E-45 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS21745 342ac5f5ab1b1ae95467d01e339832ab 2119 SUPERFAMILY SSF51735 1738 1966 4.23E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS21745 342ac5f5ab1b1ae95467d01e339832ab 2119 SUPERFAMILY SSF55048 668 731 1.83E-10 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CU254_RS21745 342ac5f5ab1b1ae95467d01e339832ab 2119 Gene3D G3DSA:3.40.47.10 17 284 3.9E-83 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS21745 342ac5f5ab1b1ae95467d01e339832ab 2119 Pfam PF00698 Acyl transferase domain 545 829 3.3E-58 T 28-03-2018 IPR014043 Acyl transferase CU254_RS21745 342ac5f5ab1b1ae95467d01e339832ab 2119 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1740 1920 3.9E-42 T 28-03-2018 CU254_RS21745 342ac5f5ab1b1ae95467d01e339832ab 2119 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 280 397 4.2E-39 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CU254_RS21745 342ac5f5ab1b1ae95467d01e339832ab 2119 SUPERFAMILY SSF52151 724 841 1.07E-72 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CU254_RS21745 342ac5f5ab1b1ae95467d01e339832ab 2119 SUPERFAMILY SSF52151 542 663 1.07E-72 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CU254_RS21745 342ac5f5ab1b1ae95467d01e339832ab 2119 Pfam PF00107 Zinc-binding dehydrogenase 1551 1640 1.6E-20 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CU254_RS21745 342ac5f5ab1b1ae95467d01e339832ab 2119 SMART SM01294 2016 2083 7.8E-8 T 28-03-2018 CU254_RS21745 342ac5f5ab1b1ae95467d01e339832ab 2119 Gene3D G3DSA:3.40.366.10 541 679 5.0E-49 T 28-03-2018 CU254_RS21745 342ac5f5ab1b1ae95467d01e339832ab 2119 SMART SM00826 904 1078 1.6E-30 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS21745 342ac5f5ab1b1ae95467d01e339832ab 2119 Pfam PF08659 KR domain 1741 1919 2.5E-55 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS21745 342ac5f5ab1b1ae95467d01e339832ab 2119 Pfam PF00550 Phosphopantetheine attachment site 2017 2083 2.0E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS21745 342ac5f5ab1b1ae95467d01e339832ab 2119 Gene3D G3DSA:3.90.180.10 1402 1541 6.3E-32 T 28-03-2018 CU254_RS21745 342ac5f5ab1b1ae95467d01e339832ab 2119 Gene3D G3DSA:3.90.180.10 1635 1723 5.7E-4 T 28-03-2018 CU254_RS21745 342ac5f5ab1b1ae95467d01e339832ab 2119 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 400 507 1.1E-11 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS21745 342ac5f5ab1b1ae95467d01e339832ab 2119 Gene3D G3DSA:1.10.1200.10 2008 2116 6.9E-20 T 28-03-2018 CU254_RS21745 342ac5f5ab1b1ae95467d01e339832ab 2119 SUPERFAMILY SSF53901 423 444 7.69E-97 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS21745 342ac5f5ab1b1ae95467d01e339832ab 2119 SUPERFAMILY SSF53901 19 393 7.69E-97 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS21745 342ac5f5ab1b1ae95467d01e339832ab 2119 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 545 839 2.4E-104 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CU254_RS21745 342ac5f5ab1b1ae95467d01e339832ab 2119 Gene3D G3DSA:3.40.50.720 1542 1634 1.3E-19 T 28-03-2018 CU254_RS21745 342ac5f5ab1b1ae95467d01e339832ab 2119 SUPERFAMILY SSF51735 1512 1691 1.86E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS21745 342ac5f5ab1b1ae95467d01e339832ab 2119 SMART SM00829 1406 1720 8.3E-137 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CU254_RS21745 342ac5f5ab1b1ae95467d01e339832ab 2119 SUPERFAMILY SSF50129 1401 1541 5.19E-27 T 28-03-2018 IPR011032 GroES-like CU254_RS21745 342ac5f5ab1b1ae95467d01e339832ab 2119 Gene3D G3DSA:3.40.47.10 285 446 1.6E-57 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS21745 342ac5f5ab1b1ae95467d01e339832ab 2119 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 185 201 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CU254_RS21745 342ac5f5ab1b1ae95467d01e339832ab 2119 Gene3D G3DSA:3.40.50.720 1733 1994 1.0E-47 T 28-03-2018 CU254_RS21745 342ac5f5ab1b1ae95467d01e339832ab 2119 Gene3D G3DSA:3.30.70.250 680 720 4.0E-18 T 28-03-2018 CU254_RS21745 342ac5f5ab1b1ae95467d01e339832ab 2119 SMART SM00823 Phosphopantetheine attachment site 2015 2087 1.2E-22 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS21745 342ac5f5ab1b1ae95467d01e339832ab 2119 Gene3D G3DSA:3.40.366.10 721 841 3.9E-26 T 28-03-2018 CU254_RS21745 342ac5f5ab1b1ae95467d01e339832ab 2119 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 22 272 3.5E-86 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CU254_RS21745 342ac5f5ab1b1ae95467d01e339832ab 2119 SUPERFAMILY SSF47336 2008 2094 5.76E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS03370 226600b4ddf43b94a6b24dc0d913e11e 233 Pfam PF00072 Response regulator receiver domain 2 112 9.4E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS03370 226600b4ddf43b94a6b24dc0d913e11e 233 SMART SM00862 141 230 2.8E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS03370 226600b4ddf43b94a6b24dc0d913e11e 233 Gene3D G3DSA:3.40.50.2300 1 116 7.3E-37 T 28-03-2018 CU254_RS03370 226600b4ddf43b94a6b24dc0d913e11e 233 SUPERFAMILY SSF46894 120 232 5.95E-22 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS03370 226600b4ddf43b94a6b24dc0d913e11e 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 142 230 7.8E-20 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS03370 226600b4ddf43b94a6b24dc0d913e11e 233 SMART SM00448 1 111 3.0E-38 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS03370 226600b4ddf43b94a6b24dc0d913e11e 233 Gene3D G3DSA:1.10.10.10 117 233 3.6E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS03370 226600b4ddf43b94a6b24dc0d913e11e 233 SUPERFAMILY SSF52172 2 119 8.11E-40 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS37380 e5098eee430f33592f8fa58c98c8456c 282 Gene3D G3DSA:3.40.50.720 3 229 5.0E-29 T 28-03-2018 CU254_RS37380 e5098eee430f33592f8fa58c98c8456c 282 SUPERFAMILY SSF51735 4 274 6.35E-53 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS37380 e5098eee430f33592f8fa58c98c8456c 282 Pfam PF05368 NmrA-like family 5 216 9.9E-20 T 28-03-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 CU254_RS13510 146e16faf9cfa09c188e915616228cfa 469 SMART SM00387 358 467 1.7E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS13510 146e16faf9cfa09c188e915616228cfa 469 Gene3D G3DSA:3.30.565.10 329 469 1.4E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS13510 146e16faf9cfa09c188e915616228cfa 469 Pfam PF00672 HAMP domain 194 242 7.2E-13 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS13510 146e16faf9cfa09c188e915616228cfa 469 SUPERFAMILY SSF158472 194 243 1.96E-8 T 28-03-2018 CU254_RS13510 146e16faf9cfa09c188e915616228cfa 469 SUPERFAMILY SSF47384 237 320 5.89E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS13510 146e16faf9cfa09c188e915616228cfa 469 SMART SM00388 253 320 7.2E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS13510 146e16faf9cfa09c188e915616228cfa 469 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 359 466 2.1E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS13510 146e16faf9cfa09c188e915616228cfa 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 427 445 5.5E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS13510 146e16faf9cfa09c188e915616228cfa 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 411 421 5.5E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS13510 146e16faf9cfa09c188e915616228cfa 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 393 407 5.5E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS13510 146e16faf9cfa09c188e915616228cfa 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 451 464 5.5E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS13510 146e16faf9cfa09c188e915616228cfa 469 SMART SM00304 193 245 9.4E-15 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS13510 146e16faf9cfa09c188e915616228cfa 469 Gene3D G3DSA:1.10.287.130 243 316 1.4E-13 T 28-03-2018 CU254_RS13510 146e16faf9cfa09c188e915616228cfa 469 Pfam PF00512 His Kinase A (phospho-acceptor) domain 255 320 1.2E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS13510 146e16faf9cfa09c188e915616228cfa 469 SUPERFAMILY SSF55874 309 465 5.11E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS20845 fd6078e2e86938751f5670673362038a 183 SUPERFAMILY SSF48498 83 176 3.29E-7 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS20845 fd6078e2e86938751f5670673362038a 183 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 91 172 7.5E-7 T 28-03-2018 CU254_RS20845 fd6078e2e86938751f5670673362038a 183 Gene3D G3DSA:1.10.357.10 3 182 1.5E-27 T 28-03-2018 CU254_RS20845 fd6078e2e86938751f5670673362038a 183 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 51 1.7E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS20845 fd6078e2e86938751f5670673362038a 183 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 7 20 1.7E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS20845 fd6078e2e86938751f5670673362038a 183 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 51 1.4E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS20845 fd6078e2e86938751f5670673362038a 183 SUPERFAMILY SSF46689 4 73 1.33E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS20845 fd6078e2e86938751f5670673362038a 183 ProSitePatterns PS01081 TetR-type HTH domain signature. 19 50 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CU254_RS32900 a996904dc856cc6f55010932f5343955 663 Gene3D G3DSA:3.40.30.10 1 171 1.5E-27 T 28-03-2018 CU254_RS32900 a996904dc856cc6f55010932f5343955 663 Pfam PF07221 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) 220 312 0.055 T 28-03-2018 CU254_RS32900 a996904dc856cc6f55010932f5343955 663 Pfam PF07221 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) 467 499 0.12 T 28-03-2018 CU254_RS32900 a996904dc856cc6f55010932f5343955 663 Pfam PF03190 Protein of unknown function, DUF255 3 163 8.8E-72 T 28-03-2018 IPR004879 Domain of unknown function DUF255 CU254_RS32900 a996904dc856cc6f55010932f5343955 663 PIRSF PIRSF006402 1 663 5.1E-196 T 28-03-2018 IPR024705 Spermatogenesis-associated protein 20 CU254_RS32900 a996904dc856cc6f55010932f5343955 663 SUPERFAMILY SSF48208 189 526 1.08E-72 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CU254_RS32900 a996904dc856cc6f55010932f5343955 663 SUPERFAMILY SSF52833 2 128 1.39E-28 T 28-03-2018 IPR012336 Thioredoxin-like fold CU254_RS32900 a996904dc856cc6f55010932f5343955 663 Gene3D G3DSA:1.50.10.10 357 579 2.6E-31 T 28-03-2018 CU254_RS32900 a996904dc856cc6f55010932f5343955 663 Gene3D G3DSA:1.50.10.10 216 356 8.6E-23 T 28-03-2018 CU254_RS33655 8e741a7049fffcc0750ee366de1a600c 184 SUPERFAMILY SSF88946 10 118 1.44E-22 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS33655 8e741a7049fffcc0750ee366de1a600c 184 Gene3D G3DSA:1.10.10.10 100 184 5.4E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS33655 8e741a7049fffcc0750ee366de1a600c 184 Pfam PF04542 Sigma-70 region 2 29 98 4.3E-8 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS33655 8e741a7049fffcc0750ee366de1a600c 184 Gene3D G3DSA:1.10.1740.10 7 99 1.4E-20 T 28-03-2018 CU254_RS33655 8e741a7049fffcc0750ee366de1a600c 184 SUPERFAMILY SSF88659 127 183 3.71E-12 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS33655 8e741a7049fffcc0750ee366de1a600c 184 Pfam PF08281 Sigma-70, region 4 129 178 1.3E-12 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS33655 8e741a7049fffcc0750ee366de1a600c 184 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 25 183 1.1E-18 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS06330 c3b187ec4fda3351491ce4cb0c4727d3 446 SMART SM00829 52 416 1.9E-9 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CU254_RS06330 c3b187ec4fda3351491ce4cb0c4727d3 446 Gene3D G3DSA:3.90.180.10 18 417 1.1E-60 T 28-03-2018 CU254_RS06330 c3b187ec4fda3351491ce4cb0c4727d3 446 TIGRFAM TIGR01751 crot-CoA-red: crotonyl-CoA carboxylase/reductase 32 429 5.6E-185 T 28-03-2018 IPR010085 Crotonyl-CoA reductase GO:0043880 KEGG: 00650+1.3.1.86 CU254_RS06330 c3b187ec4fda3351491ce4cb0c4727d3 446 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 116 191 1.1E-5 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CU254_RS06330 c3b187ec4fda3351491ce4cb0c4727d3 446 SUPERFAMILY SSF51735 199 393 1.13E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS06330 c3b187ec4fda3351491ce4cb0c4727d3 446 Pfam PF00107 Zinc-binding dehydrogenase 237 381 1.2E-36 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CU254_RS06330 c3b187ec4fda3351491ce4cb0c4727d3 446 SUPERFAMILY SSF50129 52 231 1.22E-27 T 28-03-2018 IPR011032 GroES-like CU254_RS13005 672481484c6400fd9939f7adffdf5ffa 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 245 3.7E-59 T 28-03-2018 CU254_RS13005 672481484c6400fd9939f7adffdf5ffa 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 3.5E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS13005 672481484c6400fd9939f7adffdf5ffa 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 3.5E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS13005 672481484c6400fd9939f7adffdf5ffa 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 3.5E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS13005 672481484c6400fd9939f7adffdf5ffa 250 SUPERFAMILY SSF51735 5 246 2.86E-75 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS13005 672481484c6400fd9939f7adffdf5ffa 250 Gene3D G3DSA:3.40.50.720 1 49 1.1E-12 T 28-03-2018 CU254_RS13005 672481484c6400fd9939f7adffdf5ffa 250 Gene3D G3DSA:3.40.50.720 50 249 3.0E-52 T 28-03-2018 CU254_RS13005 672481484c6400fd9939f7adffdf5ffa 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 4.8E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS13005 672481484c6400fd9939f7adffdf5ffa 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 4.8E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS13005 672481484c6400fd9939f7adffdf5ffa 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 4.8E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS13005 672481484c6400fd9939f7adffdf5ffa 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 4.8E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS13005 672481484c6400fd9939f7adffdf5ffa 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 4.8E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS13005 672481484c6400fd9939f7adffdf5ffa 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 4.8E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS13005 672481484c6400fd9939f7adffdf5ffa 250 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS02375 77719d0522e0c890a8f730926a207629 537 SUPERFAMILY SSF52029 183 374 5.41E-73 T 28-03-2018 IPR027409 GroEL-like apical domain CU254_RS02375 77719d0522e0c890a8f730926a207629 537 PRINTS PR00298 60kDa chaperonin signature 266 289 1.4E-66 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CU254_RS02375 77719d0522e0c890a8f730926a207629 537 PRINTS PR00298 60kDa chaperonin signature 82 109 1.4E-66 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CU254_RS02375 77719d0522e0c890a8f730926a207629 537 PRINTS PR00298 60kDa chaperonin signature 396 417 1.4E-66 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CU254_RS02375 77719d0522e0c890a8f730926a207629 537 PRINTS PR00298 60kDa chaperonin signature 348 373 1.4E-66 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CU254_RS02375 77719d0522e0c890a8f730926a207629 537 PRINTS PR00298 60kDa chaperonin signature 26 52 1.4E-66 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CU254_RS02375 77719d0522e0c890a8f730926a207629 537 Gene3D G3DSA:1.10.560.10 372 514 9.3E-23 T 28-03-2018 IPR027413 GroEL-like equatorial domain CU254_RS02375 77719d0522e0c890a8f730926a207629 537 SUPERFAMILY SSF48592 1 135 1.56E-72 T 28-03-2018 CU254_RS02375 77719d0522e0c890a8f730926a207629 537 SUPERFAMILY SSF48592 406 523 1.56E-72 T 28-03-2018 CU254_RS02375 77719d0522e0c890a8f730926a207629 537 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 522 4.5E-84 T 28-03-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 CU254_RS02375 77719d0522e0c890a8f730926a207629 537 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 524 3.4E-224 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CU254_RS02375 77719d0522e0c890a8f730926a207629 537 Gene3D G3DSA:1.10.560.10 1 200 3.0E-36 T 28-03-2018 IPR027413 GroEL-like equatorial domain CU254_RS02375 77719d0522e0c890a8f730926a207629 537 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 28-03-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CU254_RS02375 77719d0522e0c890a8f730926a207629 537 Hamap MF_00600 60 kDa chaperonin [groL]. 1 535 38.663 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CU254_RS02375 77719d0522e0c890a8f730926a207629 537 Gene3D G3DSA:3.50.7.10 201 371 4.9E-82 T 28-03-2018 IPR027409 GroEL-like apical domain CU254_RS02375 77719d0522e0c890a8f730926a207629 537 SUPERFAMILY SSF54849 136 203 3.89E-19 T 28-03-2018 CU254_RS02260 688a3dab4e97c27bae5e9029474c7821 373 SMART SM01005 240 369 5.1E-61 T 28-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CU254_RS02260 688a3dab4e97c27bae5e9029474c7821 373 Gene3D G3DSA:3.20.20.10 14 214 5.2E-47 T 28-03-2018 IPR029066 PLP-binding barrel CU254_RS02260 688a3dab4e97c27bae5e9029474c7821 373 Gene3D G3DSA:2.40.37.10 215 373 2.4E-65 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CU254_RS02260 688a3dab4e97c27bae5e9029474c7821 373 SUPERFAMILY SSF50621 233 370 3.84E-47 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CU254_RS02260 688a3dab4e97c27bae5e9029474c7821 373 Pfam PF01168 Alanine racemase, N-terminal domain 12 230 1.2E-65 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CU254_RS02260 688a3dab4e97c27bae5e9029474c7821 373 TIGRFAM TIGR00492 alr: alanine racemase 10 369 4.3E-91 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CU254_RS02260 688a3dab4e97c27bae5e9029474c7821 373 SUPERFAMILY SSF51419 12 241 1.24E-60 T 28-03-2018 IPR029066 PLP-binding barrel CU254_RS02260 688a3dab4e97c27bae5e9029474c7821 373 Pfam PF00842 Alanine racemase, C-terminal domain 240 368 1.8E-43 T 28-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CU254_RS02260 688a3dab4e97c27bae5e9029474c7821 373 Hamap MF_01201 Alanine racemase. 5 369 32.377 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CU254_RS02260 688a3dab4e97c27bae5e9029474c7821 373 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 35 45 - T 28-03-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CU254_RS02260 688a3dab4e97c27bae5e9029474c7821 373 PRINTS PR00992 Alanine racemase signature 294 311 2.0E-60 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CU254_RS02260 688a3dab4e97c27bae5e9029474c7821 373 PRINTS PR00992 Alanine racemase signature 161 172 2.0E-60 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CU254_RS02260 688a3dab4e97c27bae5e9029474c7821 373 PRINTS PR00992 Alanine racemase signature 30 46 2.0E-60 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CU254_RS02260 688a3dab4e97c27bae5e9029474c7821 373 PRINTS PR00992 Alanine racemase signature 66 84 2.0E-60 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CU254_RS02260 688a3dab4e97c27bae5e9029474c7821 373 PRINTS PR00992 Alanine racemase signature 273 288 2.0E-60 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CU254_RS02260 688a3dab4e97c27bae5e9029474c7821 373 PRINTS PR00992 Alanine racemase signature 127 139 2.0E-60 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CU254_RS02260 688a3dab4e97c27bae5e9029474c7821 373 PRINTS PR00992 Alanine racemase signature 203 230 2.0E-60 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CU254_RS02260 688a3dab4e97c27bae5e9029474c7821 373 PRINTS PR00992 Alanine racemase signature 256 271 2.0E-60 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CU254_RS02260 688a3dab4e97c27bae5e9029474c7821 373 PRINTS PR00992 Alanine racemase signature 350 363 2.0E-60 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CU254_RS25855 3faca504c2c5e03f2b69dbd799c78880 314 SUPERFAMILY SSF56091 4 195 1.92E-46 T 28-03-2018 CU254_RS25855 3faca504c2c5e03f2b69dbd799c78880 314 Pfam PF04679 ATP dependent DNA ligase C terminal region 215 304 3.6E-28 T 28-03-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 CU254_RS25855 3faca504c2c5e03f2b69dbd799c78880 314 Gene3D G3DSA:3.30.1490.70 141 184 1.2E-13 T 28-03-2018 CU254_RS25855 3faca504c2c5e03f2b69dbd799c78880 314 Pfam PF01068 ATP dependent DNA ligase domain 17 194 1.6E-34 T 28-03-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 CU254_RS25855 3faca504c2c5e03f2b69dbd799c78880 314 Gene3D G3DSA:3.30.470.30 2 140 5.8E-34 T 28-03-2018 CU254_RS25855 3faca504c2c5e03f2b69dbd799c78880 314 TIGRFAM TIGR02779 NHEJ_ligase_lig: DNA ligase D, ligase domain 9 309 7.5E-86 T 28-03-2018 IPR014146 DNA ligase D, ligase domain CU254_RS25855 3faca504c2c5e03f2b69dbd799c78880 314 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 27 35 - T 28-03-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 CU254_RS25855 3faca504c2c5e03f2b69dbd799c78880 314 SUPERFAMILY SSF50249 198 312 2.01E-30 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CU254_RS25855 3faca504c2c5e03f2b69dbd799c78880 314 Gene3D G3DSA:2.40.50.140 185 306 9.2E-35 T 28-03-2018 CU254_RS16125 3d398b3ac10918b02b5877cc368845e3 963 Pfam PF00668 Condensation domain 557 960 1.3E-73 T 28-03-2018 IPR001242 Condensation domain CU254_RS16125 3d398b3ac10918b02b5877cc368845e3 963 Gene3D G3DSA:1.10.1200.10 482 545 5.5E-23 T 28-03-2018 CU254_RS16125 3d398b3ac10918b02b5877cc368845e3 963 SUPERFAMILY SSF47336 468 541 1.03E-18 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS16125 3d398b3ac10918b02b5877cc368845e3 963 ProSitePatterns PS00455 Putative AMP-binding domain signature. 130 141 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS16125 3d398b3ac10918b02b5877cc368845e3 963 Gene3D G3DSA:3.30.559.10 546 727 2.9E-39 T 28-03-2018 CU254_RS16125 3d398b3ac10918b02b5877cc368845e3 963 Gene3D G3DSA:3.40.50.980 136 287 4.1E-41 T 28-03-2018 CU254_RS16125 3d398b3ac10918b02b5877cc368845e3 963 Pfam PF13193 AMP-binding enzyme C-terminal domain 378 448 1.0E-11 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS16125 3d398b3ac10918b02b5877cc368845e3 963 Gene3D G3DSA:3.40.50.980 2 135 1.2E-35 T 28-03-2018 CU254_RS16125 3d398b3ac10918b02b5877cc368845e3 963 SUPERFAMILY SSF56801 16 489 4.97E-145 T 28-03-2018 CU254_RS16125 3d398b3ac10918b02b5877cc368845e3 963 SMART SM00823 Phosphopantetheine attachment site 476 545 4.5E-9 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS16125 3d398b3ac10918b02b5877cc368845e3 963 SUPERFAMILY SSF52777 558 723 7.45E-39 T 28-03-2018 CU254_RS16125 3d398b3ac10918b02b5877cc368845e3 963 Gene3D G3DSA:3.30.300.30 365 481 9.2E-37 T 28-03-2018 CU254_RS16125 3d398b3ac10918b02b5877cc368845e3 963 Gene3D G3DSA:2.30.38.10 288 360 6.4E-16 T 28-03-2018 CU254_RS16125 3d398b3ac10918b02b5877cc368845e3 963 Pfam PF00501 AMP-binding enzyme 17 369 5.6E-88 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS16125 3d398b3ac10918b02b5877cc368845e3 963 Pfam PF00550 Phosphopantetheine attachment site 478 540 1.2E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS16125 3d398b3ac10918b02b5877cc368845e3 963 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 28 393 2.5E-120 T 28-03-2018 IPR010071 Amino acid adenylation domain CU254_RS16125 3d398b3ac10918b02b5877cc368845e3 963 SUPERFAMILY SSF52777 716 956 3.19E-51 T 28-03-2018 CU254_RS35140 46a83a18d038ef807642b4dff0ad9767 206 Gene3D G3DSA:3.40.50.1000 71 206 4.5E-18 T 28-03-2018 IPR023214 HAD-like domain CU254_RS35140 46a83a18d038ef807642b4dff0ad9767 206 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 167 4.9E-11 T 28-03-2018 IPR023214 HAD-like domain CU254_RS35140 46a83a18d038ef807642b4dff0ad9767 206 Gene3D G3DSA:1.10.150.240 32 70 6.6E-7 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CU254_RS35140 46a83a18d038ef807642b4dff0ad9767 206 SUPERFAMILY SSF56784 5 197 4.69E-35 T 28-03-2018 IPR023214 HAD-like domain CU254_RS35140 46a83a18d038ef807642b4dff0ad9767 206 Gene3D G3DSA:3.40.50.1000 3 31 0.043 T 28-03-2018 IPR023214 HAD-like domain CU254_RS23590 552272e6d591ff7feb9361199c7eb974 873 Gene3D G3DSA:3.40.228.10 13 117 9.0E-22 T 28-03-2018 CU254_RS23590 552272e6d591ff7feb9361199c7eb974 873 Gene3D G3DSA:3.40.228.10 583 675 2.0E-13 T 28-03-2018 CU254_RS23590 552272e6d591ff7feb9361199c7eb974 873 Pfam PF00384 Molybdopterin oxidoreductase 15 418 8.7E-18 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS23590 552272e6d591ff7feb9361199c7eb974 873 Pfam PF00384 Molybdopterin oxidoreductase 448 490 2.7E-7 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS23590 552272e6d591ff7feb9361199c7eb974 873 Pfam PF01568 Molydopterin dinucleotide binding domain 727 844 9.0E-12 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CU254_RS23590 552272e6d591ff7feb9361199c7eb974 873 Gene3D G3DSA:2.40.40.20 676 852 2.1E-32 T 28-03-2018 CU254_RS23590 552272e6d591ff7feb9361199c7eb974 873 SUPERFAMILY SSF53706 185 686 1.7E-191 T 28-03-2018 CU254_RS23590 552272e6d591ff7feb9361199c7eb974 873 SUPERFAMILY SSF53706 3 146 1.7E-191 T 28-03-2018 CU254_RS23590 552272e6d591ff7feb9361199c7eb974 873 SUPERFAMILY SSF50692 722 851 2.19E-36 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain CU254_RS23590 552272e6d591ff7feb9361199c7eb974 873 SUPERFAMILY SSF50692 665 695 2.19E-36 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain CU254_RS23590 552272e6d591ff7feb9361199c7eb974 873 Gene3D G3DSA:3.40.50.740 197 569 3.1E-51 T 28-03-2018 CU254_RS27485 40b54fdcb44d05ad2653e609c945bb9d 157 Pfam PF02502 Ribose/Galactose Isomerase 3 142 1.7E-46 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CU254_RS27485 40b54fdcb44d05ad2653e609c945bb9d 157 TIGRFAM TIGR02133 RPI_actino: ribose 5-phosphate isomerase 1 148 2.3E-63 T 28-03-2018 IPR011860 Ribose 5-phosphate isomerase GO:0004751 CU254_RS27485 40b54fdcb44d05ad2653e609c945bb9d 157 Gene3D G3DSA:3.40.1400.10 1 151 1.1E-55 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CU254_RS27485 40b54fdcb44d05ad2653e609c945bb9d 157 SUPERFAMILY SSF89623 2 151 6.02E-50 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CU254_RS27485 40b54fdcb44d05ad2653e609c945bb9d 157 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 147 5.1E-52 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CU254_RS27485 40b54fdcb44d05ad2653e609c945bb9d 157 PIRSF PIRSF005384 1 149 2.2E-47 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CU254_RS02025 bb6a97caa22495b78bbeb6638a02bd0d 179 Gene3D G3DSA:3.90.930.12 5 86 9.2E-29 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS02025 bb6a97caa22495b78bbeb6638a02bd0d 179 PIRSF PIRSF002162 1 178 1.6E-47 T 28-03-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS02025 bb6a97caa22495b78bbeb6638a02bd0d 179 Pfam PF00347 Ribosomal protein L6 92 165 2.5E-19 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS02025 bb6a97caa22495b78bbeb6638a02bd0d 179 Pfam PF00347 Ribosomal protein L6 11 83 2.3E-18 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS02025 bb6a97caa22495b78bbeb6638a02bd0d 179 Gene3D G3DSA:3.90.930.12 87 179 1.7E-39 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS02025 bb6a97caa22495b78bbeb6638a02bd0d 179 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 177 1.9E-74 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CU254_RS02025 bb6a97caa22495b78bbeb6638a02bd0d 179 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 155 163 - T 28-03-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS02025 bb6a97caa22495b78bbeb6638a02bd0d 179 SUPERFAMILY SSF56053 1 83 2.09E-25 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS02025 bb6a97caa22495b78bbeb6638a02bd0d 179 SUPERFAMILY SSF56053 84 178 1.57E-35 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS02025 bb6a97caa22495b78bbeb6638a02bd0d 179 PRINTS PR00059 Ribosomal protein L6 signature 100 116 1.6E-32 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CU254_RS02025 bb6a97caa22495b78bbeb6638a02bd0d 179 PRINTS PR00059 Ribosomal protein L6 signature 142 163 1.6E-32 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CU254_RS02025 bb6a97caa22495b78bbeb6638a02bd0d 179 PRINTS PR00059 Ribosomal protein L6 signature 72 97 1.6E-32 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CU254_RS02025 bb6a97caa22495b78bbeb6638a02bd0d 179 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 177 38.726 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CU254_RS23850 e152a1dd755ef4bc60a7b2442d34e29a 507 SMART SM01002 143 308 1.7E-68 T 28-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CU254_RS23850 e152a1dd755ef4bc60a7b2442d34e29a 507 SUPERFAMILY SSF51735 134 309 4.31E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS23850 e152a1dd755ef4bc60a7b2442d34e29a 507 SMART SM01003 4 134 2.6E-62 T 28-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CU254_RS23850 e152a1dd755ef4bc60a7b2442d34e29a 507 TIGRFAM TIGR00561 pntA: NAD(P)(+) transhydrogenase (AB-specific), alpha subunit 3 506 1.1E-211 T 28-03-2018 IPR026255 NAD(P) transhydrogenase, alpha subunit GO:0008746|GO:0015992|GO:0055114 KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 CU254_RS23850 e152a1dd755ef4bc60a7b2442d34e29a 507 Pfam PF12769 4TM region of pyridine nucleotide transhydrogenase, mitoch 423 506 1.4E-31 T 28-03-2018 IPR024605 NAD(P) transhydrogenase, alpha subunit, C-terminal KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 CU254_RS23850 e152a1dd755ef4bc60a7b2442d34e29a 507 Gene3D G3DSA:3.40.50.720 194 374 2.1E-53 T 28-03-2018 CU254_RS23850 e152a1dd755ef4bc60a7b2442d34e29a 507 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 138 365 7.4E-67 T 28-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CU254_RS23850 e152a1dd755ef4bc60a7b2442d34e29a 507 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 167 192 - T 28-03-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 Reactome: R-HSA-71403 CU254_RS23850 e152a1dd755ef4bc60a7b2442d34e29a 507 Gene3D G3DSA:3.40.50.720 1 191 4.3E-44 T 28-03-2018 CU254_RS23850 e152a1dd755ef4bc60a7b2442d34e29a 507 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 134 5.9E-42 T 28-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CU254_RS23850 e152a1dd755ef4bc60a7b2442d34e29a 507 SUPERFAMILY SSF52283 1 165 4.51E-50 T 28-03-2018 CU254_RS23850 e152a1dd755ef4bc60a7b2442d34e29a 507 PIRSF PIRSF000203 1 506 1.3E-222 T 28-03-2018 IPR026255 NAD(P) transhydrogenase, alpha subunit GO:0008746|GO:0015992|GO:0055114 KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 CU254_RS26780 076f10c35cd44fd0ec0fe4562bc981e4 572 Pfam PF00750 tRNA synthetases class I (R) 111 444 2.9E-103 T 28-03-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 CU254_RS26780 076f10c35cd44fd0ec0fe4562bc981e4 572 SUPERFAMILY SSF52374 114 449 2.16E-85 T 28-03-2018 CU254_RS26780 076f10c35cd44fd0ec0fe4562bc981e4 572 Pfam PF05746 DALR anticodon binding domain 458 572 5.1E-32 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CU254_RS26780 076f10c35cd44fd0ec0fe4562bc981e4 572 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 10 572 3.0E-150 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CU254_RS26780 076f10c35cd44fd0ec0fe4562bc981e4 572 Hamap MF_00123 Arginine--tRNA ligase [argS]. 8 572 25.595 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CU254_RS26780 076f10c35cd44fd0ec0fe4562bc981e4 572 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 127 138 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CU254_RS26780 076f10c35cd44fd0ec0fe4562bc981e4 572 Gene3D G3DSA:1.10.730.10 439 572 1.1E-42 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CU254_RS26780 076f10c35cd44fd0ec0fe4562bc981e4 572 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 9 91 7.8E-18 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CU254_RS26780 076f10c35cd44fd0ec0fe4562bc981e4 572 SUPERFAMILY SSF47323 452 572 7.19E-33 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CU254_RS26780 076f10c35cd44fd0ec0fe4562bc981e4 572 SMART SM01016 8 91 1.1E-21 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CU254_RS26780 076f10c35cd44fd0ec0fe4562bc981e4 572 PRINTS PR01038 Arginyl-tRNA synthetase signature 134 150 9.3E-22 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CU254_RS26780 076f10c35cd44fd0ec0fe4562bc981e4 572 PRINTS PR01038 Arginyl-tRNA synthetase signature 303 324 9.3E-22 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CU254_RS26780 076f10c35cd44fd0ec0fe4562bc981e4 572 PRINTS PR01038 Arginyl-tRNA synthetase signature 119 134 9.3E-22 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CU254_RS26780 076f10c35cd44fd0ec0fe4562bc981e4 572 PRINTS PR01038 Arginyl-tRNA synthetase signature 158 171 9.3E-22 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CU254_RS26780 076f10c35cd44fd0ec0fe4562bc981e4 572 Gene3D G3DSA:3.40.50.620 111 438 1.8E-56 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS26780 076f10c35cd44fd0ec0fe4562bc981e4 572 SMART SM00836 458 572 2.2E-39 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CU254_RS26780 076f10c35cd44fd0ec0fe4562bc981e4 572 Gene3D G3DSA:3.30.1360.70 2 109 1.0E-23 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CU254_RS26780 076f10c35cd44fd0ec0fe4562bc981e4 572 SUPERFAMILY SSF55190 8 104 2.62E-18 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CU254_RS30215 cddf278016df044c7d592a2b6ea98463 522 Gene3D G3DSA:3.90.226.10 262 519 1.7E-71 T 28-03-2018 CU254_RS30215 cddf278016df044c7d592a2b6ea98463 522 SUPERFAMILY SSF52096 11 262 7.87E-71 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS30215 cddf278016df044c7d592a2b6ea98463 522 Pfam PF01039 Carboxyl transferase domain 34 519 3.0E-189 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 CU254_RS30215 cddf278016df044c7d592a2b6ea98463 522 Gene3D G3DSA:3.90.226.10 5 261 4.1E-73 T 28-03-2018 CU254_RS30215 cddf278016df044c7d592a2b6ea98463 522 SUPERFAMILY SSF52096 258 522 2.62E-85 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS13035 ba66f028879b225b83ac19cd0dff387f 392 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 4 106 4.0E-12 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS13035 ba66f028879b225b83ac19cd0dff387f 392 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 110 193 1.4E-19 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CU254_RS13035 ba66f028879b225b83ac19cd0dff387f 392 Gene3D G3DSA:2.40.110.10 107 203 4.1E-32 T 28-03-2018 CU254_RS13035 ba66f028879b225b83ac19cd0dff387f 392 Gene3D G3DSA:1.20.140.10 204 386 1.6E-33 T 28-03-2018 CU254_RS13035 ba66f028879b225b83ac19cd0dff387f 392 SUPERFAMILY SSF56645 6 229 9.82E-66 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS13035 ba66f028879b225b83ac19cd0dff387f 392 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 216 373 1.6E-17 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS13035 ba66f028879b225b83ac19cd0dff387f 392 Gene3D G3DSA:1.10.540.10 1 106 9.4E-19 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS13035 ba66f028879b225b83ac19cd0dff387f 392 SUPERFAMILY SSF47203 216 375 1.18E-15 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS24275 42e5ccdab30db5d7b64ccaaef2c60e2d 448 Pfam PF00672 HAMP domain 170 219 1.5E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS24275 42e5ccdab30db5d7b64ccaaef2c60e2d 448 Gene3D G3DSA:1.10.287.130 236 282 1.3E-13 T 28-03-2018 CU254_RS24275 42e5ccdab30db5d7b64ccaaef2c60e2d 448 Pfam PF00512 His Kinase A (phospho-acceptor) domain 232 297 9.7E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS24275 42e5ccdab30db5d7b64ccaaef2c60e2d 448 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 337 443 2.5E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS24275 42e5ccdab30db5d7b64ccaaef2c60e2d 448 SMART SM00388 230 297 7.2E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS24275 42e5ccdab30db5d7b64ccaaef2c60e2d 448 Gene3D G3DSA:3.30.450.20 77 235 0.0012 T 28-03-2018 CU254_RS24275 42e5ccdab30db5d7b64ccaaef2c60e2d 448 SUPERFAMILY SSF55874 287 443 4.71E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS24275 42e5ccdab30db5d7b64ccaaef2c60e2d 448 SUPERFAMILY SSF47384 214 298 3.34E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS24275 42e5ccdab30db5d7b64ccaaef2c60e2d 448 SMART SM00304 170 222 7.2E-15 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS24275 42e5ccdab30db5d7b64ccaaef2c60e2d 448 SUPERFAMILY SSF158472 170 220 1.2E-8 T 28-03-2018 CU254_RS24275 42e5ccdab30db5d7b64ccaaef2c60e2d 448 Gene3D G3DSA:3.30.565.10 283 448 1.2E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS24275 42e5ccdab30db5d7b64ccaaef2c60e2d 448 PRINTS PR00344 Bacterial sensor protein C-terminal signature 405 423 9.8E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS24275 42e5ccdab30db5d7b64ccaaef2c60e2d 448 PRINTS PR00344 Bacterial sensor protein C-terminal signature 371 385 9.8E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS24275 42e5ccdab30db5d7b64ccaaef2c60e2d 448 PRINTS PR00344 Bacterial sensor protein C-terminal signature 389 399 9.8E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS24275 42e5ccdab30db5d7b64ccaaef2c60e2d 448 PRINTS PR00344 Bacterial sensor protein C-terminal signature 428 441 9.8E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS24275 42e5ccdab30db5d7b64ccaaef2c60e2d 448 SMART SM00387 336 444 5.0E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS04230 b44bdf9f75ef421f7ed712b75c258f8b 227 SMART SM00345 1 59 7.3E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS04230 b44bdf9f75ef421f7ed712b75c258f8b 227 SUPERFAMILY SSF46785 3 63 1.03E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS04230 b44bdf9f75ef421f7ed712b75c258f8b 227 SUPERFAMILY SSF48008 86 218 4.97E-21 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS04230 b44bdf9f75ef421f7ed712b75c258f8b 227 Gene3D G3DSA:1.20.120.530 82 225 1.3E-23 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS04230 b44bdf9f75ef421f7ed712b75c258f8b 227 SMART SM00895 88 212 3.9E-15 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS04230 b44bdf9f75ef421f7ed712b75c258f8b 227 Pfam PF00392 Bacterial regulatory proteins, gntR family 3 59 1.4E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS04230 b44bdf9f75ef421f7ed712b75c258f8b 227 Pfam PF07729 FCD domain 89 211 1.3E-19 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS04230 b44bdf9f75ef421f7ed712b75c258f8b 227 Gene3D G3DSA:1.10.10.10 1 71 7.4E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS26795 3be73dd5d9e7ce546fbf9dcf97be6d30 381 Gene3D G3DSA:2.40.110.10 120 216 2.4E-29 T 28-03-2018 CU254_RS26795 3be73dd5d9e7ce546fbf9dcf97be6d30 381 Gene3D G3DSA:1.20.140.10 217 380 3.2E-40 T 28-03-2018 CU254_RS26795 3be73dd5d9e7ce546fbf9dcf97be6d30 381 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 117 6.7E-23 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS26795 3be73dd5d9e7ce546fbf9dcf97be6d30 381 PIRSF PIRSF016578 6 358 9.6E-14 T 28-03-2018 CU254_RS26795 3be73dd5d9e7ce546fbf9dcf97be6d30 381 SUPERFAMILY SSF47203 224 377 8.22E-43 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS26795 3be73dd5d9e7ce546fbf9dcf97be6d30 381 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 226 375 7.8E-37 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS26795 3be73dd5d9e7ce546fbf9dcf97be6d30 381 SUPERFAMILY SSF56645 1 225 7.2E-61 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS26795 3be73dd5d9e7ce546fbf9dcf97be6d30 381 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 213 8.0E-18 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CU254_RS26795 3be73dd5d9e7ce546fbf9dcf97be6d30 381 Gene3D G3DSA:1.10.540.10 1 119 2.3E-29 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS28280 0295a0b79d96227d84ee0beefcec35d6 766 SUPERFAMILY SSF54665 14 158 7.59E-44 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CU254_RS28280 0295a0b79d96227d84ee0beefcec35d6 766 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 33 138 1.5E-32 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CU254_RS28280 0295a0b79d96227d84ee0beefcec35d6 766 Gene3D G3DSA:3.30.365.10 275 426 4.5E-45 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CU254_RS28280 0295a0b79d96227d84ee0beefcec35d6 766 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 157 702 1.9E-141 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CU254_RS28280 0295a0b79d96227d84ee0beefcec35d6 766 SUPERFAMILY SSF56003 131 758 1.83E-154 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CU254_RS28280 0295a0b79d96227d84ee0beefcec35d6 766 SMART SM01008 33 139 1.2E-51 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CU254_RS28280 0295a0b79d96227d84ee0beefcec35d6 766 Gene3D G3DSA:3.30.365.10 472 603 3.6E-18 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CU254_RS28280 0295a0b79d96227d84ee0beefcec35d6 766 Gene3D G3DSA:3.30.365.10 168 274 3.9E-30 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CU254_RS28280 0295a0b79d96227d84ee0beefcec35d6 766 Gene3D G3DSA:3.90.1170.50 17 139 1.7E-39 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CU254_RS28280 0295a0b79d96227d84ee0beefcec35d6 766 TIGRFAM TIGR03196 pucD: xanthine dehydrogenase D subunit 19 757 2.8E-250 T 28-03-2018 IPR017609 Xanthine dehydrogenase D subunit KEGG: 00230+1.17.1.4|MetaCyc: PWY-5497|MetaCyc: PWY-5695|MetaCyc: PWY-6538|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-6999 CU254_RS28280 0295a0b79d96227d84ee0beefcec35d6 766 Gene3D G3DSA:3.30.365.10 604 766 3.1E-47 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CU254_RS07380 fa938d58715d6c7d7aa1ff2ac0fc4515 255 SUPERFAMILY SSF51735 6 247 3.71E-81 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS07380 fa938d58715d6c7d7aa1ff2ac0fc4515 255 Gene3D G3DSA:3.40.50.720 50 253 3.9E-61 T 28-03-2018 CU254_RS07380 fa938d58715d6c7d7aa1ff2ac0fc4515 255 Gene3D G3DSA:3.40.50.720 1 49 2.5E-12 T 28-03-2018 CU254_RS07380 fa938d58715d6c7d7aa1ff2ac0fc4515 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 3.9E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS07380 fa938d58715d6c7d7aa1ff2ac0fc4515 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 3.9E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS07380 fa938d58715d6c7d7aa1ff2ac0fc4515 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 3.9E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS07380 fa938d58715d6c7d7aa1ff2ac0fc4515 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.3E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS07380 fa938d58715d6c7d7aa1ff2ac0fc4515 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.3E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS07380 fa938d58715d6c7d7aa1ff2ac0fc4515 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.3E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS07380 fa938d58715d6c7d7aa1ff2ac0fc4515 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 1.3E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS07380 fa938d58715d6c7d7aa1ff2ac0fc4515 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 1.3E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS07380 fa938d58715d6c7d7aa1ff2ac0fc4515 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.3E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS07380 fa938d58715d6c7d7aa1ff2ac0fc4515 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 248 4.0E-71 T 28-03-2018 CU254_RS35215 4c6490ca7d61b9c31d1ef661139ade63 134 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 7 40 1.4E-8 T 28-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 CU254_RS35215 4c6490ca7d61b9c31d1ef661139ade63 134 Pfam PF03459 TOBE domain 66 125 1.7E-9 T 28-03-2018 IPR005116 Transport-associated OB, type 1 CU254_RS35215 4c6490ca7d61b9c31d1ef661139ade63 134 Gene3D G3DSA:1.10.1660.10 2 58 1.7E-8 T 28-03-2018 CU254_RS35215 4c6490ca7d61b9c31d1ef661139ade63 134 Pfam PF12728 Helix-turn-helix domain 6 39 7.6E-8 T 28-03-2018 CU254_RS35215 4c6490ca7d61b9c31d1ef661139ade63 134 SUPERFAMILY SSF50331 10 127 2.43E-16 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CU254_RS35215 4c6490ca7d61b9c31d1ef661139ade63 134 Gene3D G3DSA:2.40.50.100 59 124 4.5E-16 T 28-03-2018 CU254_RS13985 803ecf2684e8be15a10433e640c245f0 268 SUPERFAMILY SSF52540 3 235 1.33E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS13985 803ecf2684e8be15a10433e640c245f0 268 SMART SM00382 30 230 6.5E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS13985 803ecf2684e8be15a10433e640c245f0 268 Pfam PF00005 ABC transporter 21 171 5.6E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS13985 803ecf2684e8be15a10433e640c245f0 268 Gene3D G3DSA:3.40.50.300 1 243 1.3E-50 T 28-03-2018 CU254_RS12085 71fa6192c15c1a739c40d9cd2e231b9a 564 SUPERFAMILY SSF52540 322 553 1.03E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS12085 71fa6192c15c1a739c40d9cd2e231b9a 564 SUPERFAMILY SSF90123 15 286 3.79E-21 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CU254_RS12085 71fa6192c15c1a739c40d9cd2e231b9a 564 Gene3D G3DSA:1.20.1560.10 9 294 1.0E-17 T 28-03-2018 CU254_RS12085 71fa6192c15c1a739c40d9cd2e231b9a 564 SMART SM00382 354 531 4.6E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS12085 71fa6192c15c1a739c40d9cd2e231b9a 564 Pfam PF00005 ABC transporter 346 487 9.0E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS12085 71fa6192c15c1a739c40d9cd2e231b9a 564 Gene3D G3DSA:3.40.50.300 316 560 2.3E-51 T 28-03-2018 CU254_RS12085 71fa6192c15c1a739c40d9cd2e231b9a 564 ProSitePatterns PS00211 ABC transporters family signature. 460 474 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS34605 f3ea1fe504b1d60f34040747c9bbd231 225 SUPERFAMILY SSF48008 82 217 2.51E-25 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS34605 f3ea1fe504b1d60f34040747c9bbd231 225 SUPERFAMILY SSF46785 11 81 9.0E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS34605 f3ea1fe504b1d60f34040747c9bbd231 225 Gene3D G3DSA:1.10.10.10 4 85 9.6E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS34605 f3ea1fe504b1d60f34040747c9bbd231 225 Gene3D G3DSA:1.20.120.530 86 224 3.1E-24 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS34605 f3ea1fe504b1d60f34040747c9bbd231 225 SMART SM00895 87 209 4.9E-12 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS34605 f3ea1fe504b1d60f34040747c9bbd231 225 SMART SM00345 19 77 1.8E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS34605 f3ea1fe504b1d60f34040747c9bbd231 225 Pfam PF07729 FCD domain 87 204 2.5E-13 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS34605 f3ea1fe504b1d60f34040747c9bbd231 225 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 77 4.0E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS02200 20a137b145d2fd8c3f3a0d144f2a7e81 150 PIRSF PIRSF002181 4 150 3.5E-50 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CU254_RS02200 20a137b145d2fd8c3f3a0d144f2a7e81 150 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 7 141 2.1E-62 T 28-03-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS02200 20a137b145d2fd8c3f3a0d144f2a7e81 150 Pfam PF00572 Ribosomal protein L13 15 138 7.7E-58 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CU254_RS02200 20a137b145d2fd8c3f3a0d144f2a7e81 150 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 146 29.294 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CU254_RS02200 20a137b145d2fd8c3f3a0d144f2a7e81 150 Gene3D G3DSA:3.90.1180.10 1 150 1.0E-62 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CU254_RS02200 20a137b145d2fd8c3f3a0d144f2a7e81 150 ProSitePatterns PS00783 Ribosomal protein L13 signature. 105 127 - T 28-03-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 CU254_RS02200 20a137b145d2fd8c3f3a0d144f2a7e81 150 SUPERFAMILY SSF52161 4 142 2.22E-60 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CU254_RS01985 e40d02f1a733c0e8ca6ccdb80a37a060 138 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 1.2E-53 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS01985 e40d02f1a733c0e8ca6ccdb80a37a060 138 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 28-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS01985 e40d02f1a733c0e8ca6ccdb80a37a060 138 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 9.3E-47 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CU254_RS01985 e40d02f1a733c0e8ca6ccdb80a37a060 138 Gene3D G3DSA:3.90.1170.10 3 138 8.2E-49 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CU254_RS01985 e40d02f1a733c0e8ca6ccdb80a37a060 138 SUPERFAMILY SSF54686 2 136 1.31E-54 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CU254_RS01985 e40d02f1a733c0e8ca6ccdb80a37a060 138 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 36.983 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS01985 e40d02f1a733c0e8ca6ccdb80a37a060 138 PRINTS PR00060 Ribosomal protein L16 signature 42 53 5.4E-38 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS01985 e40d02f1a733c0e8ca6ccdb80a37a060 138 PRINTS PR00060 Ribosomal protein L16 signature 24 36 5.4E-38 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS01985 e40d02f1a733c0e8ca6ccdb80a37a060 138 PRINTS PR00060 Ribosomal protein L16 signature 58 87 5.4E-38 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS01985 e40d02f1a733c0e8ca6ccdb80a37a060 138 PRINTS PR00060 Ribosomal protein L16 signature 88 117 5.4E-38 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS02430 f19296fd31c34bb4333600fc07c55505 503 PIRSF PIRSF000130 10 503 1.9E-199 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CU254_RS02430 f19296fd31c34bb4333600fc07c55505 503 SUPERFAMILY SSF54631 103 212 1.64E-29 T 28-03-2018 CU254_RS02430 f19296fd31c34bb4333600fc07c55505 503 SMART SM00116 106 154 9.0E-8 T 28-03-2018 IPR000644 CBS domain CU254_RS02430 f19296fd31c34bb4333600fc07c55505 503 SMART SM00116 167 215 1.6E-6 T 28-03-2018 IPR000644 CBS domain CU254_RS02430 f19296fd31c34bb4333600fc07c55505 503 Gene3D G3DSA:3.20.20.70 11 489 1.1E-105 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS02430 f19296fd31c34bb4333600fc07c55505 503 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 18 472 2.8E-182 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CU254_RS02430 f19296fd31c34bb4333600fc07c55505 503 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 18 489 3.9E-154 T 28-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 CU254_RS02430 f19296fd31c34bb4333600fc07c55505 503 SUPERFAMILY SSF51412 13 100 6.67E-116 T 28-03-2018 CU254_RS02430 f19296fd31c34bb4333600fc07c55505 503 SUPERFAMILY SSF51412 226 493 6.67E-116 T 28-03-2018 CU254_RS02430 f19296fd31c34bb4333600fc07c55505 503 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 305 317 - T 28-03-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 CU254_RS02430 f19296fd31c34bb4333600fc07c55505 503 SMART SM01240 17 489 0.0 T 28-03-2018 CU254_RS02430 f19296fd31c34bb4333600fc07c55505 503 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 18 502 83.23 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CU254_RS02430 f19296fd31c34bb4333600fc07c55505 503 Pfam PF00571 CBS domain 159 212 7.7E-8 T 28-03-2018 IPR000644 CBS domain CU254_RS02430 f19296fd31c34bb4333600fc07c55505 503 Pfam PF00571 CBS domain 103 151 2.3E-8 T 28-03-2018 IPR000644 CBS domain CU254_RS03875 3e0b042f3f28769f34fb4b6598b29923 279 SUPERFAMILY SSF110849 86 145 8.37E-8 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CU254_RS03875 3e0b042f3f28769f34fb4b6598b29923 279 Gene3D G3DSA:3.90.1530.10 62 151 8.2E-7 T 28-03-2018 CU254_RS35750 65d08ef3f48d5eb73f3c595f072becad 473 Gene3D G3DSA:1.10.287.130 241 299 2.7E-16 T 28-03-2018 CU254_RS35750 65d08ef3f48d5eb73f3c595f072becad 473 Pfam PF00672 HAMP domain 198 245 2.2E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS35750 65d08ef3f48d5eb73f3c595f072becad 473 SUPERFAMILY SSF55874 303 464 7.6E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS35750 65d08ef3f48d5eb73f3c595f072becad 473 SUPERFAMILY SSF158472 199 246 4.05E-7 T 28-03-2018 CU254_RS35750 65d08ef3f48d5eb73f3c595f072becad 473 Pfam PF00512 His Kinase A (phospho-acceptor) domain 251 312 2.3E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS35750 65d08ef3f48d5eb73f3c595f072becad 473 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 356 463 8.8E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS35750 65d08ef3f48d5eb73f3c595f072becad 473 SMART SM00388 251 314 7.1E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS35750 65d08ef3f48d5eb73f3c595f072becad 473 SMART SM00387 355 466 2.3E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS35750 65d08ef3f48d5eb73f3c595f072becad 473 SUPERFAMILY SSF47384 234 312 1.59E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS35750 65d08ef3f48d5eb73f3c595f072becad 473 Gene3D G3DSA:3.30.565.10 300 471 4.8E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS35750 65d08ef3f48d5eb73f3c595f072becad 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 423 441 7.3E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS35750 65d08ef3f48d5eb73f3c595f072becad 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 450 463 7.3E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS35750 65d08ef3f48d5eb73f3c595f072becad 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 408 418 7.3E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS35750 65d08ef3f48d5eb73f3c595f072becad 473 PRINTS PR00344 Bacterial sensor protein C-terminal signature 390 404 7.3E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS35750 65d08ef3f48d5eb73f3c595f072becad 473 SMART SM00304 197 250 2.1E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS11350 6ff8f0164c2c138638f531efb1ac84e1 314 SUPERFAMILY SSF51735 104 282 8.69E-57 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS11350 6ff8f0164c2c138638f531efb1ac84e1 314 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 282 1.7E-56 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CU254_RS11350 6ff8f0164c2c138638f531efb1ac84e1 314 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 22 312 1.7E-10 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CU254_RS11350 6ff8f0164c2c138638f531efb1ac84e1 314 Gene3D G3DSA:3.40.50.720 1 109 1.5E-28 T 28-03-2018 CU254_RS11350 6ff8f0164c2c138638f531efb1ac84e1 314 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 221 237 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CU254_RS11350 6ff8f0164c2c138638f531efb1ac84e1 314 SUPERFAMILY SSF52283 1 120 6.17E-24 T 28-03-2018 CU254_RS11350 6ff8f0164c2c138638f531efb1ac84e1 314 Gene3D G3DSA:3.40.50.720 110 283 2.9E-55 T 28-03-2018 CU254_RS31230 0b81851ae480ce4ca963e9eae7fb2246 197 Gene3D G3DSA:1.10.357.10 64 197 1.3E-25 T 28-03-2018 CU254_RS31230 0b81851ae480ce4ca963e9eae7fb2246 197 SUPERFAMILY SSF46689 19 71 1.75E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS31230 0b81851ae480ce4ca963e9eae7fb2246 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 2.9E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS31230 0b81851ae480ce4ca963e9eae7fb2246 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 2.9E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS31230 0b81851ae480ce4ca963e9eae7fb2246 197 Gene3D G3DSA:1.10.10.60 17 63 3.4E-16 T 28-03-2018 CU254_RS31230 0b81851ae480ce4ca963e9eae7fb2246 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 67 8.0E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS31230 0b81851ae480ce4ca963e9eae7fb2246 197 SUPERFAMILY SSF48498 79 194 2.02E-31 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS31230 0b81851ae480ce4ca963e9eae7fb2246 197 Pfam PF16859 Bacterial transcriptional repressor C-terminal 79 190 2.3E-34 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS30775 12ec9f096bad0d94c4fb21bde0d1d934 92 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 3 86 2.6E-21 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CU254_RS30775 12ec9f096bad0d94c4fb21bde0d1d934 92 Gene3D G3DSA:3.30.1340.10 2 90 6.6E-25 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CU254_RS30775 12ec9f096bad0d94c4fb21bde0d1d934 92 PRINTS PR00107 Phosphocarrier protein signature 58 75 3.9E-11 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CU254_RS30775 12ec9f096bad0d94c4fb21bde0d1d934 92 PRINTS PR00107 Phosphocarrier protein signature 43 58 3.9E-11 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CU254_RS30775 12ec9f096bad0d94c4fb21bde0d1d934 92 PRINTS PR00107 Phosphocarrier protein signature 13 29 3.9E-11 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CU254_RS30775 12ec9f096bad0d94c4fb21bde0d1d934 92 SUPERFAMILY SSF55594 2 91 6.93E-20 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CU254_RS30775 12ec9f096bad0d94c4fb21bde0d1d934 92 Pfam PF00381 PTS HPr component phosphorylation site 3 87 4.7E-23 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CU254_RS09940 eccf6968a4664fa909f5bba9f5a7c7fc 345 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 11 294 2.9E-69 T 28-03-2018 IPR005693 Virulence factor Mce protein CU254_RS09940 eccf6968a4664fa909f5bba9f5a7c7fc 345 Pfam PF02470 MlaD protein 39 112 1.1E-16 T 28-03-2018 IPR003399 Mce/MlaD CU254_RS02630 aa53bffd596e1085fedabaeca65d365e 408 Pfam PF02371 Transposase IS116/IS110/IS902 family 275 357 7.6E-13 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CU254_RS02630 aa53bffd596e1085fedabaeca65d365e 408 Pfam PF01548 Transposase 3 160 1.9E-34 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CU254_RS27110 aa53bffd596e1085fedabaeca65d365e 408 Pfam PF02371 Transposase IS116/IS110/IS902 family 275 357 7.6E-13 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CU254_RS27110 aa53bffd596e1085fedabaeca65d365e 408 Pfam PF01548 Transposase 3 160 1.9E-34 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CU254_RS05140 aa53bffd596e1085fedabaeca65d365e 408 Pfam PF02371 Transposase IS116/IS110/IS902 family 275 357 7.6E-13 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CU254_RS05140 aa53bffd596e1085fedabaeca65d365e 408 Pfam PF01548 Transposase 3 160 1.9E-34 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CU254_RS01890 aa53bffd596e1085fedabaeca65d365e 408 Pfam PF02371 Transposase IS116/IS110/IS902 family 275 357 7.6E-13 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CU254_RS01890 aa53bffd596e1085fedabaeca65d365e 408 Pfam PF01548 Transposase 3 160 1.9E-34 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CU254_RS25790 aa53bffd596e1085fedabaeca65d365e 408 Pfam PF02371 Transposase IS116/IS110/IS902 family 275 357 7.6E-13 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CU254_RS25790 aa53bffd596e1085fedabaeca65d365e 408 Pfam PF01548 Transposase 3 160 1.9E-34 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CU254_RS06060 aa53bffd596e1085fedabaeca65d365e 408 Pfam PF02371 Transposase IS116/IS110/IS902 family 275 357 7.6E-13 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CU254_RS06060 aa53bffd596e1085fedabaeca65d365e 408 Pfam PF01548 Transposase 3 160 1.9E-34 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CU254_RS29420 aa53bffd596e1085fedabaeca65d365e 408 Pfam PF02371 Transposase IS116/IS110/IS902 family 275 357 7.6E-13 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CU254_RS29420 aa53bffd596e1085fedabaeca65d365e 408 Pfam PF01548 Transposase 3 160 1.9E-34 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CU254_RS01970 a7ff01950cb4f7218f12e6fde7d71e19 93 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 28-03-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS01970 a7ff01950cb4f7218f12e6fde7d71e19 93 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 92 1.5E-47 T 28-03-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 CU254_RS01970 a7ff01950cb4f7218f12e6fde7d71e19 93 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.024 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS01970 a7ff01950cb4f7218f12e6fde7d71e19 93 SUPERFAMILY SSF54570 3 83 7.46E-35 T 28-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS01970 a7ff01950cb4f7218f12e6fde7d71e19 93 Gene3D G3DSA:3.30.860.10 1 92 1.3E-39 T 28-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS01970 a7ff01950cb4f7218f12e6fde7d71e19 93 PIRSF PIRSF002144 1 93 4.1E-30 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS01970 a7ff01950cb4f7218f12e6fde7d71e19 93 Pfam PF00203 Ribosomal protein S19 3 83 2.1E-36 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS01970 a7ff01950cb4f7218f12e6fde7d71e19 93 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 8.6E-24 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS01970 a7ff01950cb4f7218f12e6fde7d71e19 93 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 8.6E-24 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS01970 a7ff01950cb4f7218f12e6fde7d71e19 93 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 8.6E-24 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS17495 d420b3f80c94fe90644f41c2e3ffdc54 287 SUPERFAMILY SSF56436 3 286 6.03E-68 T 28-03-2018 IPR016187 C-type lectin fold CU254_RS17495 d420b3f80c94fe90644f41c2e3ffdc54 287 Gene3D G3DSA:3.90.1580.10 2 287 5.0E-67 T 28-03-2018 CU254_RS17495 d420b3f80c94fe90644f41c2e3ffdc54 287 Pfam PF03781 Sulfatase-modifying factor enzyme 1 3 284 4.7E-60 T 28-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 CU254_RS30085 a6ba84629a0f8e6256ff0b408f30e7d1 236 Pfam PF00440 Bacterial regulatory proteins, tetR family 38 81 4.1E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS30085 a6ba84629a0f8e6256ff0b408f30e7d1 236 Gene3D G3DSA:1.10.10.60 15 86 3.2E-16 T 28-03-2018 CU254_RS30085 a6ba84629a0f8e6256ff0b408f30e7d1 236 SUPERFAMILY SSF46689 25 87 6.67E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS30085 a6ba84629a0f8e6256ff0b408f30e7d1 236 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 95 234 6.1E-10 T 28-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 CU254_RS30085 a6ba84629a0f8e6256ff0b408f30e7d1 236 Gene3D G3DSA:1.10.357.10 88 236 6.0E-23 T 28-03-2018 CU254_RS30085 a6ba84629a0f8e6256ff0b408f30e7d1 236 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 50 5.5E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS30085 a6ba84629a0f8e6256ff0b408f30e7d1 236 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 58 81 5.5E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS30085 a6ba84629a0f8e6256ff0b408f30e7d1 236 SUPERFAMILY SSF48498 99 235 5.45E-15 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS05430 9c84fadea9a779f4fcabba9b2e834c98 202 Gene3D G3DSA:1.10.10.10 128 202 5.7E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS05430 9c84fadea9a779f4fcabba9b2e834c98 202 SUPERFAMILY SSF46894 126 202 1.53E-16 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS05430 9c84fadea9a779f4fcabba9b2e834c98 202 SMART SM00448 3 116 2.5E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS05430 9c84fadea9a779f4fcabba9b2e834c98 202 Pfam PF00196 Bacterial regulatory proteins, luxR family 141 196 1.0E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS05430 9c84fadea9a779f4fcabba9b2e834c98 202 SMART SM00421 139 196 1.2E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS05430 9c84fadea9a779f4fcabba9b2e834c98 202 Gene3D G3DSA:3.40.50.2300 2 127 5.8E-32 T 28-03-2018 CU254_RS05430 9c84fadea9a779f4fcabba9b2e834c98 202 Pfam PF00072 Response regulator receiver domain 6 116 4.7E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS05430 9c84fadea9a779f4fcabba9b2e834c98 202 SUPERFAMILY SSF52172 3 129 1.21E-29 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS05430 9c84fadea9a779f4fcabba9b2e834c98 202 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 172 3.3E-6 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS05430 9c84fadea9a779f4fcabba9b2e834c98 202 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 184 3.3E-6 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS05430 9c84fadea9a779f4fcabba9b2e834c98 202 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 142 156 3.3E-6 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS02110 437f927c9bacc501ed0dae6bc764de2c 278 PIRSF PIRSF001430 1 273 1.4E-62 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CU254_RS02110 437f927c9bacc501ed0dae6bc764de2c 278 Gene3D G3DSA:3.30.70.660 119 255 3.3E-26 T 28-03-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 CU254_RS02110 437f927c9bacc501ed0dae6bc764de2c 278 Pfam PF01416 tRNA pseudouridine synthase 157 257 7.7E-21 T 28-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CU254_RS02110 437f927c9bacc501ed0dae6bc764de2c 278 Pfam PF01416 tRNA pseudouridine synthase 4 71 3.6E-5 T 28-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CU254_RS02110 437f927c9bacc501ed0dae6bc764de2c 278 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 2 249 2.1E-43 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CU254_RS02110 437f927c9bacc501ed0dae6bc764de2c 278 Gene3D G3DSA:3.30.70.580 1 118 9.4E-30 T 28-03-2018 CU254_RS02110 437f927c9bacc501ed0dae6bc764de2c 278 SUPERFAMILY SSF55120 1 263 1.27E-65 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CU254_RS02110 437f927c9bacc501ed0dae6bc764de2c 278 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 1 256 27.895 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CU254_RS02035 3382b049af875f4770aab8000fbfceaa 213 SUPERFAMILY SSF54768 46 111 2.93E-22 T 28-03-2018 CU254_RS02035 3382b049af875f4770aab8000fbfceaa 213 Pfam PF00333 Ribosomal protein S5, N-terminal domain 48 110 1.0E-27 T 28-03-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 CU254_RS02035 3382b049af875f4770aab8000fbfceaa 213 SUPERFAMILY SSF54211 114 193 4.55E-24 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CU254_RS02035 3382b049af875f4770aab8000fbfceaa 213 Pfam PF03719 Ribosomal protein S5, C-terminal domain 122 192 1.7E-27 T 28-03-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 CU254_RS02035 3382b049af875f4770aab8000fbfceaa 213 Gene3D G3DSA:3.30.230.10 112 201 1.2E-28 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CU254_RS02035 3382b049af875f4770aab8000fbfceaa 213 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 23 198 34.276 T 28-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 CU254_RS02035 3382b049af875f4770aab8000fbfceaa 213 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 47 198 3.6E-67 T 28-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 CU254_RS02035 3382b049af875f4770aab8000fbfceaa 213 Gene3D G3DSA:3.30.160.20 47 106 1.0E-25 T 28-03-2018 CU254_RS02035 3382b049af875f4770aab8000fbfceaa 213 ProSitePatterns PS00585 Ribosomal protein S5 signature. 63 95 - T 28-03-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site CU254_RS18610 f4328199dcf811e587a4a0a7313df8f7 266 Pfam PF01614 Bacterial transcriptional regulator 139 258 1.0E-28 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal CU254_RS18610 f4328199dcf811e587a4a0a7313df8f7 266 SUPERFAMILY SSF46785 22 95 2.82E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS18610 f4328199dcf811e587a4a0a7313df8f7 266 Pfam PF09339 IclR helix-turn-helix domain 24 74 4.9E-14 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS18610 f4328199dcf811e587a4a0a7313df8f7 266 Gene3D G3DSA:1.10.10.10 21 83 1.1E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS18610 f4328199dcf811e587a4a0a7313df8f7 266 Gene3D G3DSA:3.30.450.40 93 266 2.0E-52 T 28-03-2018 IPR029016 GAF domain-like CU254_RS18610 f4328199dcf811e587a4a0a7313df8f7 266 SUPERFAMILY SSF55781 87 266 2.09E-49 T 28-03-2018 IPR029016 GAF domain-like CU254_RS18610 f4328199dcf811e587a4a0a7313df8f7 266 SMART SM00346 22 111 3.9E-18 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS36045 bf2796116d72a1bb1522b56227f53f52 561 SMART SM01120 381 554 5.8E-45 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CU254_RS36045 bf2796116d72a1bb1522b56227f53f52 561 Pfam PF02733 Dak1 domain 17 325 6.6E-109 T 28-03-2018 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CU254_RS36045 bf2796116d72a1bb1522b56227f53f52 561 Gene3D G3DSA:3.30.1180.20 184 331 2.0E-43 T 28-03-2018 CU254_RS36045 bf2796116d72a1bb1522b56227f53f52 561 SUPERFAMILY SSF101473 354 552 1.22E-41 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CU254_RS36045 bf2796116d72a1bb1522b56227f53f52 561 Pfam PF02734 DAK2 domain 382 552 2.2E-40 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CU254_RS36045 bf2796116d72a1bb1522b56227f53f52 561 SUPERFAMILY SSF82549 12 328 1.6E-105 T 28-03-2018 CU254_RS36045 bf2796116d72a1bb1522b56227f53f52 561 Gene3D G3DSA:3.40.50.10440 12 183 1.2E-57 T 28-03-2018 CU254_RS36935 0ba41ca3ffd20c0d0590eae66658ba03 421 SUPERFAMILY SSF55021 333 409 2.75E-22 T 28-03-2018 CU254_RS36935 0ba41ca3ffd20c0d0590eae66658ba03 421 Gene3D G3DSA:3.30.70.260 336 421 4.6E-21 T 28-03-2018 CU254_RS36935 0ba41ca3ffd20c0d0590eae66658ba03 421 Pfam PF00696 Amino acid kinase family 3 231 3.0E-54 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CU254_RS36935 0ba41ca3ffd20c0d0590eae66658ba03 421 Gene3D G3DSA:3.30.70.260 236 335 6.6E-21 T 28-03-2018 CU254_RS36935 0ba41ca3ffd20c0d0590eae66658ba03 421 PIRSF PIRSF000726 1 61 1.7E-21 T 28-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CU254_RS36935 0ba41ca3ffd20c0d0590eae66658ba03 421 PIRSF PIRSF000726 57 414 2.1E-126 T 28-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CU254_RS36935 0ba41ca3ffd20c0d0590eae66658ba03 421 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 63 406 1.1E-114 T 28-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CU254_RS36935 0ba41ca3ffd20c0d0590eae66658ba03 421 Gene3D G3DSA:3.40.1160.10 1 235 2.0E-74 T 28-03-2018 CU254_RS36935 0ba41ca3ffd20c0d0590eae66658ba03 421 Pfam PF01842 ACT domain 269 329 1.9E-8 T 28-03-2018 IPR002912 ACT domain CU254_RS36935 0ba41ca3ffd20c0d0590eae66658ba03 421 PRINTS PR00474 Glutamate 5-kinase family signature 205 225 4.4E-5 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CU254_RS36935 0ba41ca3ffd20c0d0590eae66658ba03 421 PRINTS PR00474 Glutamate 5-kinase family signature 33 47 4.4E-5 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CU254_RS36935 0ba41ca3ffd20c0d0590eae66658ba03 421 PRINTS PR00474 Glutamate 5-kinase family signature 153 180 4.4E-5 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CU254_RS36935 0ba41ca3ffd20c0d0590eae66658ba03 421 SUPERFAMILY SSF53633 4 243 4.45E-72 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CU254_RS36935 0ba41ca3ffd20c0d0590eae66658ba03 421 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 28-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CU254_RS36935 0ba41ca3ffd20c0d0590eae66658ba03 421 Pfam PF13840 ACT domain 341 403 2.3E-14 T 28-03-2018 IPR027795 GATS-like ACT domain CU254_RS36935 0ba41ca3ffd20c0d0590eae66658ba03 421 SUPERFAMILY SSF55021 251 330 8.36E-17 T 28-03-2018 CU254_RS00925 9da014b90df89ad99c2a09283889f02a 297 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 31 293 2.1E-44 T 28-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 CU254_RS00925 9da014b90df89ad99c2a09283889f02a 297 SUPERFAMILY SSF53850 31 296 8.69E-46 T 28-03-2018 CU254_RS00925 9da014b90df89ad99c2a09283889f02a 297 Gene3D G3DSA:3.40.190.10 19 169 5.2E-24 T 28-03-2018 CU254_RS00925 9da014b90df89ad99c2a09283889f02a 297 Gene3D G3DSA:3.40.190.10 174 297 5.2E-14 T 28-03-2018 CU254_RS37145 1f5bafe393399bdce532d10d32afd03b 487 SUPERFAMILY SSF47384 256 335 7.85E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS37145 1f5bafe393399bdce532d10d32afd03b 487 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 377 485 1.0E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS37145 1f5bafe393399bdce532d10d32afd03b 487 Pfam PF00672 HAMP domain 197 254 6.5E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS37145 1f5bafe393399bdce532d10d32afd03b 487 SMART SM00388 267 334 9.8E-20 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS37145 1f5bafe393399bdce532d10d32afd03b 487 PRINTS PR00344 Bacterial sensor protein C-terminal signature 414 428 2.9E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS37145 1f5bafe393399bdce532d10d32afd03b 487 PRINTS PR00344 Bacterial sensor protein C-terminal signature 432 442 2.9E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS37145 1f5bafe393399bdce532d10d32afd03b 487 PRINTS PR00344 Bacterial sensor protein C-terminal signature 449 467 2.9E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS37145 1f5bafe393399bdce532d10d32afd03b 487 SMART SM00387 377 487 1.1E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS37145 1f5bafe393399bdce532d10d32afd03b 487 Pfam PF00512 His Kinase A (phospho-acceptor) domain 269 334 2.4E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS37145 1f5bafe393399bdce532d10d32afd03b 487 SMART SM00304 197 259 4.5E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS37145 1f5bafe393399bdce532d10d32afd03b 487 SUPERFAMILY SSF55874 323 485 1.7E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS37145 1f5bafe393399bdce532d10d32afd03b 487 Gene3D G3DSA:3.30.565.10 338 487 6.6E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS37145 1f5bafe393399bdce532d10d32afd03b 487 Gene3D G3DSA:1.10.287.130 246 330 2.3E-15 T 28-03-2018 CU254_RS33705 1df8450b71595aea392c23e7f6caa013 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 207 2.6E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS33705 1df8450b71595aea392c23e7f6caa013 217 Gene3D G3DSA:3.40.50.2300 1 133 5.8E-38 T 28-03-2018 CU254_RS33705 1df8450b71595aea392c23e7f6caa013 217 SMART SM00448 2 115 2.0E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS33705 1df8450b71595aea392c23e7f6caa013 217 SUPERFAMILY SSF52172 1 135 7.4E-34 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS33705 1df8450b71595aea392c23e7f6caa013 217 Pfam PF00072 Response regulator receiver domain 4 115 2.7E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS33705 1df8450b71595aea392c23e7f6caa013 217 ProSitePatterns PS00622 LuxR-type HTH domain signature. 167 194 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS33705 1df8450b71595aea392c23e7f6caa013 217 SUPERFAMILY SSF46894 142 213 2.31E-21 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS33705 1df8450b71595aea392c23e7f6caa013 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 1.5E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS33705 1df8450b71595aea392c23e7f6caa013 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 1.5E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS33705 1df8450b71595aea392c23e7f6caa013 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 1.5E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS33705 1df8450b71595aea392c23e7f6caa013 217 Gene3D G3DSA:1.10.10.10 134 212 4.1E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS33705 1df8450b71595aea392c23e7f6caa013 217 SMART SM00421 150 207 2.6E-25 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS03235 a50bba6fe55291b8863c9b92c33ddbfb 203 TIGRFAM TIGR00172 maf: septum formation protein Maf 3 191 3.4E-47 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 CU254_RS03235 a50bba6fe55291b8863c9b92c33ddbfb 203 Gene3D G3DSA:3.90.950.10 1 201 7.6E-63 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CU254_RS03235 a50bba6fe55291b8863c9b92c33ddbfb 203 Pfam PF02545 Maf-like protein 2 193 2.9E-44 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 CU254_RS03235 a50bba6fe55291b8863c9b92c33ddbfb 203 Hamap MF_00528 Septum formation protein Maf [maf]. 2 198 27.516 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 CU254_RS03235 a50bba6fe55291b8863c9b92c33ddbfb 203 PIRSF PIRSF006305 1 200 3.6E-42 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 CU254_RS03235 a50bba6fe55291b8863c9b92c33ddbfb 203 SUPERFAMILY SSF52972 2 193 7.19E-48 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CU254_RS07690 afcebc89075c620c678227a7dc620965 170 Pfam PF13302 Acetyltransferase (GNAT) domain 12 155 1.9E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS07690 afcebc89075c620c678227a7dc620965 170 SUPERFAMILY SSF55729 12 157 5.14E-19 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS07690 afcebc89075c620c678227a7dc620965 170 Gene3D G3DSA:3.40.630.30 10 160 1.9E-19 T 28-03-2018 CU254_RS09010 ca608bf7fc85f4f3635eea3305e5cf55 389 Pfam PF00082 Subtilase family 58 306 5.8E-15 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS09010 ca608bf7fc85f4f3635eea3305e5cf55 389 Gene3D G3DSA:3.40.50.200 40 335 1.2E-48 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS09010 ca608bf7fc85f4f3635eea3305e5cf55 389 PRINTS PR00723 Subtilisin serine protease family (S8) signature 92 105 1.2E-8 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CU254_RS09010 ca608bf7fc85f4f3635eea3305e5cf55 389 PRINTS PR00723 Subtilisin serine protease family (S8) signature 58 77 1.2E-8 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CU254_RS09010 ca608bf7fc85f4f3635eea3305e5cf55 389 PRINTS PR00723 Subtilisin serine protease family (S8) signature 256 272 1.2E-8 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CU254_RS09010 ca608bf7fc85f4f3635eea3305e5cf55 389 SUPERFAMILY SSF52743 40 317 8.12E-47 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS10690 04793261145a71550cfba075311329e7 510 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 236 242 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CU254_RS10690 04793261145a71550cfba075311329e7 510 Pfam PF05175 Methyltransferase small domain 156 245 1.6E-15 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 CU254_RS10690 04793261145a71550cfba075311329e7 510 SUPERFAMILY SSF53335 162 303 2.71E-21 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS10690 04793261145a71550cfba075311329e7 510 Gene3D G3DSA:3.40.50.150 147 354 5.4E-19 T 28-03-2018 CU254_RS37070 0d58a72aff6724f307bb807269067d81 339 Pfam PF00535 Glycosyl transferase family 2 11 107 4.4E-19 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CU254_RS37070 0d58a72aff6724f307bb807269067d81 339 Gene3D G3DSA:3.90.550.10 2 257 9.7E-32 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS37070 0d58a72aff6724f307bb807269067d81 339 SUPERFAMILY SSF53448 5 239 2.81E-34 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS41915 7c5ea8a1c4b0a6022dc495ca96af1a05 535 Gene3D G3DSA:3.90.120.10 367 511 4.5E-12 T 28-03-2018 CU254_RS41915 7c5ea8a1c4b0a6022dc495ca96af1a05 535 Gene3D G3DSA:3.40.50.150 1 227 1.6E-32 T 28-03-2018 CU254_RS41915 7c5ea8a1c4b0a6022dc495ca96af1a05 535 Pfam PF00145 C-5 cytosine-specific DNA methylase 4 189 2.1E-14 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS41915 7c5ea8a1c4b0a6022dc495ca96af1a05 535 SUPERFAMILY SSF53335 431 525 3.54E-46 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS41915 7c5ea8a1c4b0a6022dc495ca96af1a05 535 SUPERFAMILY SSF53335 5 200 3.54E-46 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS21350 512f994591873337f68d6e01bab5a2b3 290 Gene3D G3DSA:2.40.290.10 1 181 3.2E-32 T 28-03-2018 IPR016194 SPOC-like, C-terminal domain CU254_RS21350 512f994591873337f68d6e01bab5a2b3 290 SMART SM00559 52 180 1.4E-29 T 28-03-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 CU254_RS21350 512f994591873337f68d6e01bab5a2b3 290 SUPERFAMILY SSF100939 1 259 1.29E-52 T 28-03-2018 IPR016194 SPOC-like, C-terminal domain CU254_RS21350 512f994591873337f68d6e01bab5a2b3 290 PIRSF PIRSF006493 1 288 2.1E-88 T 28-03-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type CU254_RS21350 512f994591873337f68d6e01bab5a2b3 290 Pfam PF02735 Ku70/Ku80 beta-barrel domain 11 188 3.3E-38 T 28-03-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 CU254_RS21350 512f994591873337f68d6e01bab5a2b3 290 Hamap MF_01875 Non-homologous end joining protein Ku [ku]. 1 254 32.382 T 28-03-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type CU254_RS21350 512f994591873337f68d6e01bab5a2b3 290 TIGRFAM TIGR02772 Ku_bact: Ku protein 1 257 2.9E-87 T 28-03-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type CU254_RS05880 f6cb9ec2c65a3f4f0f63af91b45952e8 363 Pfam PF00266 Aminotransferase class-V 57 354 3.1E-11 T 28-03-2018 IPR000192 Aminotransferase class V domain CU254_RS05880 f6cb9ec2c65a3f4f0f63af91b45952e8 363 SUPERFAMILY SSF53383 8 361 9.83E-59 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS05880 f6cb9ec2c65a3f4f0f63af91b45952e8 363 Gene3D G3DSA:3.40.640.10 17 273 1.2E-20 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS05880 f6cb9ec2c65a3f4f0f63af91b45952e8 363 Gene3D G3DSA:3.90.1150.10 274 363 1.2E-23 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS05880 f6cb9ec2c65a3f4f0f63af91b45952e8 363 PIRSF PIRSF000524 3 363 7.9E-53 T 28-03-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661 CU254_RS40770 1824c79ce33eaad62766c564b2d91f6a 258 Gene3D G3DSA:1.10.1740.10 22 104 1.6E-19 T 28-03-2018 CU254_RS40770 1824c79ce33eaad62766c564b2d91f6a 258 Pfam PF04542 Sigma-70 region 2 37 106 2.7E-17 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS40770 1824c79ce33eaad62766c564b2d91f6a 258 SUPERFAMILY SSF88659 105 159 5.23E-12 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS40770 1824c79ce33eaad62766c564b2d91f6a 258 Pfam PF04539 Sigma-70 region 3 118 160 5.8E-8 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS40770 1824c79ce33eaad62766c564b2d91f6a 258 PRINTS PR00046 Major sigma-70 factor signature 219 234 3.3E-9 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS40770 1824c79ce33eaad62766c564b2d91f6a 258 PRINTS PR00046 Major sigma-70 factor signature 234 245 3.3E-9 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS40770 1824c79ce33eaad62766c564b2d91f6a 258 PRINTS PR00046 Major sigma-70 factor signature 61 74 3.3E-9 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS40770 1824c79ce33eaad62766c564b2d91f6a 258 PRINTS PR00046 Major sigma-70 factor signature 202 214 3.3E-9 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS40770 1824c79ce33eaad62766c564b2d91f6a 258 Gene3D G3DSA:1.10.10.10 171 255 2.4E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS40770 1824c79ce33eaad62766c564b2d91f6a 258 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 31 248 2.6E-74 T 28-03-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS40770 1824c79ce33eaad62766c564b2d91f6a 258 SUPERFAMILY SSF88946 14 106 3.14E-26 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS40770 1824c79ce33eaad62766c564b2d91f6a 258 SUPERFAMILY SSF88659 175 250 6.35E-17 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS40770 1824c79ce33eaad62766c564b2d91f6a 258 Pfam PF04545 Sigma-70, region 4 199 246 8.0E-16 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS40770 1824c79ce33eaad62766c564b2d91f6a 258 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 34 247 1.8E-36 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS40770 1824c79ce33eaad62766c564b2d91f6a 258 Gene3D G3DSA:1.10.10.10 107 159 6.6E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS31750 7f205aaeeb435f4b227f28480341d635 471 Gene3D G3DSA:3.50.50.60 2 471 1.1E-22 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS31750 7f205aaeeb435f4b227f28480341d635 471 SUPERFAMILY SSF51905 433 469 2.78E-34 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS31750 7f205aaeeb435f4b227f28480341d635 471 SUPERFAMILY SSF51905 4 301 2.78E-34 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS31750 7f205aaeeb435f4b227f28480341d635 471 Pfam PF13450 NAD(P)-binding Rossmann-like domain 6 58 2.6E-12 T 28-03-2018 CU254_RS31750 7f205aaeeb435f4b227f28480341d635 471 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 1.2E-6 T 28-03-2018 CU254_RS31750 7f205aaeeb435f4b227f28480341d635 471 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 306 321 1.2E-6 T 28-03-2018 CU254_RS08635 20b7d9c5fdf2e86c7dfcf5f01d9d2ee5 253 Gene3D G3DSA:3.60.21.10 3 250 1.3E-40 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CU254_RS08635 20b7d9c5fdf2e86c7dfcf5f01d9d2ee5 253 SUPERFAMILY SSF56300 4 247 1.31E-45 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CU254_RS08635 20b7d9c5fdf2e86c7dfcf5f01d9d2ee5 253 Hamap MF_00905 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [cpdA]. 2 251 34.089 T 28-03-2018 IPR026575 3,5-cyclic adenosine monophosphate phosphodiesterase CpdA GO:0004115 KEGG: 00230+3.1.4.53 CU254_RS08635 20b7d9c5fdf2e86c7dfcf5f01d9d2ee5 253 Pfam PF00149 Calcineurin-like phosphoesterase 4 186 1.1E-18 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CU254_RS20595 50c28aca4a5009d8b83c6ded8b6d4f9d 161 PIRSF PIRSF002560 1 157 5.2E-63 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CU254_RS20595 50c28aca4a5009d8b83c6ded8b6d4f9d 161 Pfam PF00210 Ferritin-like domain 9 143 1.6E-35 T 28-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 CU254_RS20595 50c28aca4a5009d8b83c6ded8b6d4f9d 161 ProSitePatterns PS00549 Bacterioferritin signature. 1 19 - T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CU254_RS20595 50c28aca4a5009d8b83c6ded8b6d4f9d 161 SUPERFAMILY SSF47240 1 156 7.29E-48 T 28-03-2018 IPR009078 Ferritin-like superfamily CU254_RS20595 50c28aca4a5009d8b83c6ded8b6d4f9d 161 PRINTS PR00601 Bacterioferritin signature 65 85 4.5E-57 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CU254_RS20595 50c28aca4a5009d8b83c6ded8b6d4f9d 161 PRINTS PR00601 Bacterioferritin signature 107 127 4.5E-57 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CU254_RS20595 50c28aca4a5009d8b83c6ded8b6d4f9d 161 PRINTS PR00601 Bacterioferritin signature 128 149 4.5E-57 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CU254_RS20595 50c28aca4a5009d8b83c6ded8b6d4f9d 161 PRINTS PR00601 Bacterioferritin signature 86 106 4.5E-57 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CU254_RS20595 50c28aca4a5009d8b83c6ded8b6d4f9d 161 PRINTS PR00601 Bacterioferritin signature 23 43 4.5E-57 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CU254_RS20595 50c28aca4a5009d8b83c6ded8b6d4f9d 161 PRINTS PR00601 Bacterioferritin signature 3 22 4.5E-57 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CU254_RS20595 50c28aca4a5009d8b83c6ded8b6d4f9d 161 PRINTS PR00601 Bacterioferritin signature 44 64 4.5E-57 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CU254_RS20595 50c28aca4a5009d8b83c6ded8b6d4f9d 161 TIGRFAM TIGR00754 bfr: bacterioferritin 1 155 9.5E-67 T 28-03-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 CU254_RS20595 50c28aca4a5009d8b83c6ded8b6d4f9d 161 Gene3D G3DSA:1.20.1260.10 2 147 5.3E-35 T 28-03-2018 IPR012347 Ferritin-related CU254_RS19065 6381b4f12728d5974f47447cc1dd5de7 475 Gene3D G3DSA:3.50.50.60 2 380 3.3E-69 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS19065 6381b4f12728d5974f47447cc1dd5de7 475 Pfam PF01494 FAD binding domain 2 335 2.4E-96 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CU254_RS19065 6381b4f12728d5974f47447cc1dd5de7 475 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 321 337 1.2E-48 T 28-03-2018 CU254_RS19065 6381b4f12728d5974f47447cc1dd5de7 475 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 1.2E-48 T 28-03-2018 CU254_RS19065 6381b4f12728d5974f47447cc1dd5de7 475 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 143 158 1.2E-48 T 28-03-2018 CU254_RS19065 6381b4f12728d5974f47447cc1dd5de7 475 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 270 285 1.2E-48 T 28-03-2018 CU254_RS19065 6381b4f12728d5974f47447cc1dd5de7 475 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 285 301 1.2E-48 T 28-03-2018 CU254_RS19065 6381b4f12728d5974f47447cc1dd5de7 475 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 303 321 1.2E-48 T 28-03-2018 CU254_RS19065 6381b4f12728d5974f47447cc1dd5de7 475 SUPERFAMILY SSF51905 2 164 5.25E-68 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS19065 6381b4f12728d5974f47447cc1dd5de7 475 SUPERFAMILY SSF51905 257 352 5.25E-68 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS18685 1e638b7e1e62be35d711602e16838d6c 404 PIRSF PIRSF000429 1 403 5.2E-130 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CU254_RS18685 1e638b7e1e62be35d711602e16838d6c 404 Gene3D G3DSA:3.40.47.10 273 399 1.6E-31 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS18685 1e638b7e1e62be35d711602e16838d6c 404 SUPERFAMILY SSF53901 277 401 9.47E-42 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS18685 1e638b7e1e62be35d711602e16838d6c 404 SUPERFAMILY SSF53901 5 276 4.5E-79 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS18685 1e638b7e1e62be35d711602e16838d6c 404 Gene3D G3DSA:3.40.47.10 1 272 3.1E-56 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS18685 1e638b7e1e62be35d711602e16838d6c 404 Pfam PF02803 Thiolase, C-terminal domain 277 401 1.6E-42 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CU254_RS18685 1e638b7e1e62be35d711602e16838d6c 404 Pfam PF00108 Thiolase, N-terminal domain 5 268 4.9E-69 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CU254_RS18685 1e638b7e1e62be35d711602e16838d6c 404 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 400 2.4E-133 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CU254_RS24115 76571afa142ea3ca795bf4fb7380e5de 829 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 10 85 1.9E-12 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CU254_RS24115 76571afa142ea3ca795bf4fb7380e5de 829 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 40 48 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CU254_RS24115 76571afa142ea3ca795bf4fb7380e5de 829 Pfam PF00175 Oxidoreductase NAD-binding domain 211 313 6.8E-20 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CU254_RS24115 76571afa142ea3ca795bf4fb7380e5de 829 SUPERFAMILY SSF52343 203 332 2.1E-35 T 28-03-2018 CU254_RS24115 76571afa142ea3ca795bf4fb7380e5de 829 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 699 715 2.4E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS24115 76571afa142ea3ca795bf4fb7380e5de 829 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 723 742 2.4E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS24115 76571afa142ea3ca795bf4fb7380e5de 829 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 582 599 2.4E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS24115 76571afa142ea3ca795bf4fb7380e5de 829 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 651 662 2.4E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS24115 76571afa142ea3ca795bf4fb7380e5de 829 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 744 761 2.4E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS24115 76571afa142ea3ca795bf4fb7380e5de 829 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 791 811 2.4E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS24115 76571afa142ea3ca795bf4fb7380e5de 829 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 710 738 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS24115 76571afa142ea3ca795bf4fb7380e5de 829 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 587 826 3.3E-43 T 28-03-2018 CU254_RS24115 76571afa142ea3ca795bf4fb7380e5de 829 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 581 756 0.0078 T 28-03-2018 CU254_RS24115 76571afa142ea3ca795bf4fb7380e5de 829 SUPERFAMILY SSF54292 1 95 1.14E-23 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CU254_RS24115 76571afa142ea3ca795bf4fb7380e5de 829 SUPERFAMILY SSF48008 428 562 9.15E-17 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS24115 76571afa142ea3ca795bf4fb7380e5de 829 SMART SM00895 428 554 1.6E-13 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS24115 76571afa142ea3ca795bf4fb7380e5de 829 SUPERFAMILY SSF63380 107 201 8.34E-25 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CU254_RS24115 76571afa142ea3ca795bf4fb7380e5de 829 Gene3D G3DSA:3.10.20.30 1 105 1.3E-18 T 28-03-2018 IPR012675 Beta-grasp domain CU254_RS24115 76571afa142ea3ca795bf4fb7380e5de 829 Gene3D G3DSA:1.20.120.530 421 569 1.2E-20 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS24115 76571afa142ea3ca795bf4fb7380e5de 829 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 723 742 2.6E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS24115 76571afa142ea3ca795bf4fb7380e5de 829 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 705 713 2.6E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS24115 76571afa142ea3ca795bf4fb7380e5de 829 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 651 662 2.6E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS24115 76571afa142ea3ca795bf4fb7380e5de 829 Pfam PF07729 FCD domain 429 553 5.0E-16 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS24115 76571afa142ea3ca795bf4fb7380e5de 829 Pfam PF00970 Oxidoreductase FAD-binding domain 109 200 1.2E-16 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CU254_RS24115 76571afa142ea3ca795bf4fb7380e5de 829 SUPERFAMILY SSF51735 576 826 4.06E-60 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS24115 76571afa142ea3ca795bf4fb7380e5de 829 Gene3D G3DSA:2.40.30.10 106 198 7.0E-23 T 28-03-2018 CU254_RS24115 76571afa142ea3ca795bf4fb7380e5de 829 Gene3D G3DSA:3.40.50.720 571 828 1.4E-53 T 28-03-2018 CU254_RS24115 76571afa142ea3ca795bf4fb7380e5de 829 Gene3D G3DSA:3.40.50.80 199 331 1.4E-30 T 28-03-2018 CU254_RS32510 65bd21c035296f51aa4980df105fbf13 180 SMART SM00530 19 74 1.3E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS32510 65bd21c035296f51aa4980df105fbf13 180 Pfam PF13560 Helix-turn-helix domain 17 71 9.1E-11 T 28-03-2018 CU254_RS32510 65bd21c035296f51aa4980df105fbf13 180 SUPERFAMILY SSF51182 59 179 3.46E-7 T 28-03-2018 IPR011051 RmlC-like cupin domain CU254_RS32510 65bd21c035296f51aa4980df105fbf13 180 Gene3D G3DSA:1.10.260.40 13 84 7.4E-17 T 28-03-2018 CU254_RS32510 65bd21c035296f51aa4980df105fbf13 180 SUPERFAMILY SSF47413 13 79 2.03E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS10105 ffcfc97a4eb2e6d47fa9050e15c25857 341 Pfam PF00365 Phosphofructokinase 2 296 1.0E-100 T 28-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CU254_RS10105 ffcfc97a4eb2e6d47fa9050e15c25857 341 Gene3D G3DSA:3.40.50.450 197 322 4.9E-16 T 28-03-2018 CU254_RS10105 ffcfc97a4eb2e6d47fa9050e15c25857 341 ProSitePatterns PS00433 Phosphofructokinase signature. 265 283 - T 28-03-2018 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CU254_RS10105 ffcfc97a4eb2e6d47fa9050e15c25857 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 5 24 6.1E-72 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CU254_RS10105 ffcfc97a4eb2e6d47fa9050e15c25857 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 138 156 6.1E-72 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CU254_RS10105 ffcfc97a4eb2e6d47fa9050e15c25857 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 211 223 6.1E-72 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CU254_RS10105 ffcfc97a4eb2e6d47fa9050e15c25857 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 6.1E-72 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CU254_RS10105 ffcfc97a4eb2e6d47fa9050e15c25857 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 261 283 6.1E-72 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CU254_RS10105 ffcfc97a4eb2e6d47fa9050e15c25857 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 120 137 6.1E-72 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CU254_RS10105 ffcfc97a4eb2e6d47fa9050e15c25857 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 6.1E-72 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CU254_RS10105 ffcfc97a4eb2e6d47fa9050e15c25857 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 158 174 6.1E-72 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CU254_RS10105 ffcfc97a4eb2e6d47fa9050e15c25857 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 176 193 6.1E-72 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CU254_RS10105 ffcfc97a4eb2e6d47fa9050e15c25857 341 SUPERFAMILY SSF53784 1 333 1.96E-118 T 28-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CU254_RS10105 ffcfc97a4eb2e6d47fa9050e15c25857 341 Gene3D G3DSA:3.40.50.450 1 196 2.0E-68 T 28-03-2018 CU254_RS10105 ffcfc97a4eb2e6d47fa9050e15c25857 341 Hamap MF_01976 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 1 341 43.757 T 28-03-2018 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 CU254_RS10105 ffcfc97a4eb2e6d47fa9050e15c25857 341 PIRSF PIRSF000532 1 339 1.2E-118 T 28-03-2018 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 CU254_RS10105 ffcfc97a4eb2e6d47fa9050e15c25857 341 TIGRFAM TIGR02483 PFK_mixed: phosphofructokinase 2 321 1.8E-152 T 28-03-2018 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 CU254_RS13010 6d2ef72312e340b504d192581d25de05 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 135 1.2E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS13010 6d2ef72312e340b504d192581d25de05 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.2E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS13010 6d2ef72312e340b504d192581d25de05 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 164 1.2E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS13010 6d2ef72312e340b504d192581d25de05 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 1.2E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS13010 6d2ef72312e340b504d192581d25de05 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 1.2E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS13010 6d2ef72312e340b504d192581d25de05 257 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 132 160 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS13010 6d2ef72312e340b504d192581d25de05 257 SUPERFAMILY SSF51735 5 250 1.68E-55 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS13010 6d2ef72312e340b504d192581d25de05 257 Pfam PF00106 short chain dehydrogenase 5 188 9.7E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS13010 6d2ef72312e340b504d192581d25de05 257 Gene3D G3DSA:3.40.50.720 4 254 4.0E-51 T 28-03-2018 CU254_RS15525 d0af523d50fa96f84dcefc0785b4582d 167 Pfam PF00440 Bacterial regulatory proteins, tetR family 2 45 9.2E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS15525 d0af523d50fa96f84dcefc0785b4582d 167 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 1 12 9.9E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS15525 d0af523d50fa96f84dcefc0785b4582d 167 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 43 9.9E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS15525 d0af523d50fa96f84dcefc0785b4582d 167 Gene3D G3DSA:1.10.10.60 34 154 2.2E-11 T 28-03-2018 CU254_RS15525 d0af523d50fa96f84dcefc0785b4582d 167 SUPERFAMILY SSF48498 65 162 1.02E-6 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS15525 d0af523d50fa96f84dcefc0785b4582d 167 SUPERFAMILY SSF46689 1 58 1.1E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS15525 d0af523d50fa96f84dcefc0785b4582d 167 Gene3D G3DSA:1.10.10.60 1 33 3.3E-12 T 28-03-2018 CU254_RS00895 f6562abcaeffa3a45f36f2f8b6e9c829 229 SUPERFAMILY SSF58113 44 183 1.09E-5 T 28-03-2018 CU254_RS00895 f6562abcaeffa3a45f36f2f8b6e9c829 229 Gene3D G3DSA:1.20.120.20 2 112 8.7E-5 T 28-03-2018 CU254_RS00895 f6562abcaeffa3a45f36f2f8b6e9c829 229 Gene3D G3DSA:1.20.5.1230 113 220 2.0E-6 T 28-03-2018 CU254_RS00895 f6562abcaeffa3a45f36f2f8b6e9c829 229 ProDom PD082580 HEPARIN-BINDING HEMAGGLUTININ ADHESIN GLYCOPROTEIN DIRECT VIRULENCE SEQUENCING CELL ADHESION HOMOLOG 42 165 4.0E-8 T 28-03-2018 IPR020340 Heparin-binding haemagglutinin, bacteria GO:0007155|GO:0008201|GO:0009405|GO:0009986 CU254_RS01040 b7dff58d591f76d30c64fcfd389166c4 293 Gene3D G3DSA:3.20.20.100 6 293 5.7E-63 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS01040 b7dff58d591f76d30c64fcfd389166c4 293 PRINTS PR00069 Aldo-keto reductase signature 227 251 1.7E-13 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CU254_RS01040 b7dff58d591f76d30c64fcfd389166c4 293 PRINTS PR00069 Aldo-keto reductase signature 53 77 1.7E-13 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CU254_RS01040 b7dff58d591f76d30c64fcfd389166c4 293 PRINTS PR00069 Aldo-keto reductase signature 189 218 1.7E-13 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CU254_RS01040 b7dff58d591f76d30c64fcfd389166c4 293 PRINTS PR00069 Aldo-keto reductase signature 155 172 1.7E-13 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CU254_RS01040 b7dff58d591f76d30c64fcfd389166c4 293 Pfam PF00248 Aldo/keto reductase family 23 293 1.1E-44 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS01040 b7dff58d591f76d30c64fcfd389166c4 293 SUPERFAMILY SSF51430 19 292 4.06E-62 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS26105 317c5626b44b67aeb636be3eff1a6aa3 306 SUPERFAMILY SSF51197 66 294 8.24E-18 T 28-03-2018 CU254_RS26105 317c5626b44b67aeb636be3eff1a6aa3 306 Gene3D G3DSA:3.60.130.10 36 300 4.2E-21 T 28-03-2018 CU254_RS31260 aaa79d3bbfb761661a6a6535a4f1bb31 475 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 141 354 3.1E-63 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CU254_RS31260 aaa79d3bbfb761661a6a6535a4f1bb31 475 SUPERFAMILY SSF52540 88 360 3.01E-84 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS31260 aaa79d3bbfb761661a6a6535a4f1bb31 475 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 10 470 6.9E-239 T 28-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 CU254_RS31260 aaa79d3bbfb761661a6a6535a4f1bb31 475 Gene3D G3DSA:2.40.10.170 1 86 5.9E-28 T 28-03-2018 CU254_RS31260 aaa79d3bbfb761661a6a6535a4f1bb31 475 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 345 354 - T 28-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CU254_RS31260 aaa79d3bbfb761661a6a6535a4f1bb31 475 SUPERFAMILY SSF47917 357 472 3.66E-47 T 28-03-2018 CU254_RS31260 aaa79d3bbfb761661a6a6535a4f1bb31 475 Hamap MF_01347 ATP synthase subunit beta [atpB]. 8 472 53.501 T 28-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 CU254_RS31260 aaa79d3bbfb761661a6a6535a4f1bb31 475 Gene3D G3DSA:1.10.1140.10 361 470 1.6E-38 T 28-03-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CU254_RS31260 aaa79d3bbfb761661a6a6535a4f1bb31 475 SMART SM00382 153 338 1.1E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS31260 aaa79d3bbfb761661a6a6535a4f1bb31 475 Gene3D G3DSA:3.40.50.300 87 360 3.9E-86 T 28-03-2018 CU254_RS31260 aaa79d3bbfb761661a6a6535a4f1bb31 475 SUPERFAMILY SSF50615 10 86 1.52E-22 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CU254_RS31260 aaa79d3bbfb761661a6a6535a4f1bb31 475 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 13 84 5.5E-19 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CU254_RS12560 6cba8752bf0f9de54d1b4c218f8c54fe 340 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 58 72 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CU254_RS12560 6cba8752bf0f9de54d1b4c218f8c54fe 340 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 122 5.3E-24 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CU254_RS12560 6cba8752bf0f9de54d1b4c218f8c54fe 340 SUPERFAMILY SSF51735 146 307 2.79E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS12560 6cba8752bf0f9de54d1b4c218f8c54fe 340 SUPERFAMILY SSF50129 2 165 4.87E-45 T 28-03-2018 IPR011032 GroES-like CU254_RS12560 6cba8752bf0f9de54d1b4c218f8c54fe 340 Gene3D G3DSA:3.40.50.10730 160 275 2.0E-27 T 28-03-2018 CU254_RS12560 6cba8752bf0f9de54d1b4c218f8c54fe 340 Gene3D G3DSA:3.90.180.10 2 159 3.2E-36 T 28-03-2018 CU254_RS12560 6cba8752bf0f9de54d1b4c218f8c54fe 340 SMART SM00829 8 338 0.0066 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CU254_RS12560 6cba8752bf0f9de54d1b4c218f8c54fe 340 Pfam PF00107 Zinc-binding dehydrogenase 175 286 2.2E-24 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CU254_RS09440 91fc057a9048622b3d2e9769308d2872 182 Gene3D G3DSA:1.10.3300.10 12 182 1.5E-26 T 28-03-2018 IPR023286 ABATE domain CU254_RS09440 91fc057a9048622b3d2e9769308d2872 182 Pfam PF11706 CGNR zinc finger 142 180 1.3E-9 T 28-03-2018 IPR021005 Zinc finger, CGNR CU254_RS09440 91fc057a9048622b3d2e9769308d2872 182 SUPERFAMILY SSF160904 32 180 7.98E-28 T 28-03-2018 CU254_RS31820 493439fddbc08ad76f1f9effe736df91 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 50 66 5.0E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS31820 493439fddbc08ad76f1f9effe736df91 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 67 82 5.0E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS31820 493439fddbc08ad76f1f9effe736df91 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 86 102 5.0E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS31820 493439fddbc08ad76f1f9effe736df91 154 SMART SM00347 26 126 1.1E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS31820 493439fddbc08ad76f1f9effe736df91 154 Pfam PF01047 MarR family 34 84 5.9E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS31820 493439fddbc08ad76f1f9effe736df91 154 Gene3D G3DSA:1.10.10.10 10 146 1.8E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS31820 493439fddbc08ad76f1f9effe736df91 154 SUPERFAMILY SSF46785 25 139 1.3E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS29875 eb261b46b02474735f9d1443837b7de9 187 Pfam PF01794 Ferric reductase like transmembrane component 12 134 2.2E-10 T 28-03-2018 IPR013130 Ferric reductase transmembrane component-like domain CU254_RS11620 d36b81e1d74070832b48e6dffcd4393a 676 SMART SM00465 17 99 2.6E-21 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CU254_RS11620 d36b81e1d74070832b48e6dffcd4393a 676 Hamap MF_00203 UvrABC system protein C [uvrC]. 4 657 30.128 T 28-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 CU254_RS11620 d36b81e1d74070832b48e6dffcd4393a 676 Gene3D G3DSA:4.10.860.10 187 248 2.1E-14 T 28-03-2018 IPR001943 UVR domain GO:0005515 CU254_RS11620 d36b81e1d74070832b48e6dffcd4393a 676 Pfam PF02151 UvrB/uvrC motif 210 242 6.0E-8 T 28-03-2018 IPR001943 UVR domain GO:0005515 CU254_RS11620 d36b81e1d74070832b48e6dffcd4393a 676 Gene3D G3DSA:3.40.1440.10 5 102 1.3E-22 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CU254_RS11620 d36b81e1d74070832b48e6dffcd4393a 676 SUPERFAMILY SSF82771 17 101 1.7E-22 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CU254_RS11620 d36b81e1d74070832b48e6dffcd4393a 676 SUPERFAMILY SSF46600 195 247 7.06E-14 T 28-03-2018 IPR001943 UVR domain GO:0005515 CU254_RS11620 d36b81e1d74070832b48e6dffcd4393a 676 Pfam PF01541 GIY-YIG catalytic domain 19 92 9.6E-10 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CU254_RS11620 d36b81e1d74070832b48e6dffcd4393a 676 Gene3D G3DSA:1.10.150.20 591 664 1.7E-14 T 28-03-2018 CU254_RS11620 d36b81e1d74070832b48e6dffcd4393a 676 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 13 477 2.0E-123 T 28-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 CU254_RS11620 d36b81e1d74070832b48e6dffcd4393a 676 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 403 592 2.2E-47 T 28-03-2018 IPR001162 UvrC family homology region CU254_RS11620 d36b81e1d74070832b48e6dffcd4393a 676 SMART SM00278 638 657 0.15 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CU254_RS11620 d36b81e1d74070832b48e6dffcd4393a 676 SMART SM00278 606 625 16.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CU254_RS11620 d36b81e1d74070832b48e6dffcd4393a 676 Pfam PF14520 Helix-hairpin-helix domain 607 658 1.3E-9 T 28-03-2018 CU254_RS11620 d36b81e1d74070832b48e6dffcd4393a 676 SUPERFAMILY SSF47781 547 659 3.81E-24 T 28-03-2018 IPR010994 RuvA domain 2-like CU254_RS40935 1ca8647ba024f478c09222cb2b35d302 248 Pfam PF01471 Putative peptidoglycan binding domain 191 244 3.9E-16 T 28-03-2018 IPR002477 Peptidoglycan binding-like CU254_RS40935 1ca8647ba024f478c09222cb2b35d302 248 Gene3D G3DSA:1.10.260.40 14 103 1.6E-8 T 28-03-2018 CU254_RS40935 1ca8647ba024f478c09222cb2b35d302 248 SUPERFAMILY SSF47090 186 247 2.62E-18 T 28-03-2018 IPR002477 Peptidoglycan binding-like CU254_RS40935 1ca8647ba024f478c09222cb2b35d302 248 SMART SM00530 24 79 7.4E-5 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS40935 1ca8647ba024f478c09222cb2b35d302 248 Gene3D G3DSA:1.10.101.10 172 248 4.3E-19 T 28-03-2018 IPR002477 Peptidoglycan binding-like CU254_RS40935 1ca8647ba024f478c09222cb2b35d302 248 Pfam PF13560 Helix-turn-helix domain 21 82 2.8E-13 T 28-03-2018 CU254_RS40935 1ca8647ba024f478c09222cb2b35d302 248 SUPERFAMILY SSF47413 20 76 1.07E-5 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS12955 41629c7738955960718b9917811d02a9 1397 Gene3D G3DSA:3.40.50.980 533 557 1.6E-8 T 28-03-2018 CU254_RS12955 41629c7738955960718b9917811d02a9 1397 Gene3D G3DSA:3.40.50.980 425 532 3.7E-27 T 28-03-2018 CU254_RS12955 41629c7738955960718b9917811d02a9 1397 Pfam PF00550 Phosphopantetheine attachment site 909 969 1.3E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS12955 41629c7738955960718b9917811d02a9 1397 SUPERFAMILY SSF56801 421 920 1.7E-138 T 28-03-2018 CU254_RS12955 41629c7738955960718b9917811d02a9 1397 SUPERFAMILY SSF52777 983 1166 1.78E-25 T 28-03-2018 CU254_RS12955 41629c7738955960718b9917811d02a9 1397 SMART SM00823 Phosphopantetheine attachment site 907 975 0.0053 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS12955 41629c7738955960718b9917811d02a9 1397 Gene3D G3DSA:3.40.50.980 558 715 1.6E-32 T 28-03-2018 CU254_RS12955 41629c7738955960718b9917811d02a9 1397 Pfam PF00668 Condensation domain 3 397 3.0E-72 T 28-03-2018 IPR001242 Condensation domain CU254_RS12955 41629c7738955960718b9917811d02a9 1397 Pfam PF00668 Condensation domain 1014 1393 8.1E-26 T 28-03-2018 IPR001242 Condensation domain CU254_RS12955 41629c7738955960718b9917811d02a9 1397 Gene3D G3DSA:1.10.1200.10 913 967 2.3E-20 T 28-03-2018 CU254_RS12955 41629c7738955960718b9917811d02a9 1397 Gene3D G3DSA:3.30.300.30 799 912 1.1E-35 T 28-03-2018 CU254_RS12955 41629c7738955960718b9917811d02a9 1397 Gene3D G3DSA:3.30.559.10 2 181 1.1E-40 T 28-03-2018 CU254_RS12955 41629c7738955960718b9917811d02a9 1397 Gene3D G3DSA:3.30.559.10 968 1157 7.1E-25 T 28-03-2018 CU254_RS12955 41629c7738955960718b9917811d02a9 1397 ProSitePatterns PS00455 Putative AMP-binding domain signature. 551 562 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS12955 41629c7738955960718b9917811d02a9 1397 ProSitePatterns PS00012 Phosphopantetheine attachment site. 931 946 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CU254_RS12955 41629c7738955960718b9917811d02a9 1397 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 453 828 1.5E-110 T 28-03-2018 IPR010071 Amino acid adenylation domain CU254_RS12955 41629c7738955960718b9917811d02a9 1397 Pfam PF00501 AMP-binding enzyme 540 804 1.2E-63 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS12955 41629c7738955960718b9917811d02a9 1397 Pfam PF00501 AMP-binding enzyme 432 529 8.5E-23 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS12955 41629c7738955960718b9917811d02a9 1397 SUPERFAMILY SSF52777 172 398 6.08E-44 T 28-03-2018 CU254_RS12955 41629c7738955960718b9917811d02a9 1397 SUPERFAMILY SSF47336 900 969 1.27E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS12955 41629c7738955960718b9917811d02a9 1397 Pfam PF13193 AMP-binding enzyme C-terminal domain 812 884 5.0E-13 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS12955 41629c7738955960718b9917811d02a9 1397 SUPERFAMILY SSF52777 1157 1394 7.67E-30 T 28-03-2018 CU254_RS12955 41629c7738955960718b9917811d02a9 1397 SUPERFAMILY SSF52777 2 186 3.56E-45 T 28-03-2018 CU254_RS12955 41629c7738955960718b9917811d02a9 1397 Gene3D G3DSA:2.30.38.10 716 797 2.0E-24 T 28-03-2018 CU254_RS34870 d287d42f2ab19c8628c6fd3d6bb0c5af 271 SUPERFAMILY SSF56281 30 259 5.77E-28 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS34870 d287d42f2ab19c8628c6fd3d6bb0c5af 271 SMART SM00849 32 257 9.3E-14 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS34870 d287d42f2ab19c8628c6fd3d6bb0c5af 271 Pfam PF00753 Metallo-beta-lactamase superfamily 32 223 1.3E-24 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS34870 d287d42f2ab19c8628c6fd3d6bb0c5af 271 Gene3D G3DSA:3.60.15.10 16 269 2.8E-29 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS30730 f8805ad7138262561ac82e4e68fde222 151 Gene3D G3DSA:3.90.79.10 2 150 3.2E-24 T 28-03-2018 CU254_RS30730 f8805ad7138262561ac82e4e68fde222 151 PRINTS PR00502 NUDIX hydrolase family signature 53 68 6.3E-6 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CU254_RS30730 f8805ad7138262561ac82e4e68fde222 151 PRINTS PR00502 NUDIX hydrolase family signature 39 53 6.3E-6 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CU254_RS30730 f8805ad7138262561ac82e4e68fde222 151 SUPERFAMILY SSF55811 3 148 5.15E-20 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CU254_RS30730 f8805ad7138262561ac82e4e68fde222 151 ProSitePatterns PS00893 Nudix box signature. 44 65 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CU254_RS30730 f8805ad7138262561ac82e4e68fde222 151 Pfam PF00293 NUDIX domain 4 147 6.5E-18 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CU254_RS14515 c5f0a89b71e29173986664694587a648 1294 Gene3D G3DSA:2.30.38.10 325 403 4.1E-11 T 28-03-2018 CU254_RS14515 c5f0a89b71e29173986664694587a648 1294 Pfam PF13193 AMP-binding enzyme C-terminal domain 421 494 5.3E-7 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS14515 c5f0a89b71e29173986664694587a648 1294 Gene3D G3DSA:2.160.10.10 1100 1287 2.3E-14 T 28-03-2018 CU254_RS14515 c5f0a89b71e29173986664694587a648 1294 TIGRFAM TIGR02353 NRPS_term_dom: non-ribosomal peptide synthetase terminal domain of unknown function 610 1290 2.1E-193 T 28-03-2018 IPR012728 Non-ribosomal peptide synthetase, C-terminal CU254_RS14515 c5f0a89b71e29173986664694587a648 1294 SUPERFAMILY SSF51161 893 1055 3.74E-16 T 28-03-2018 IPR011004 Trimeric LpxA-like CU254_RS14515 c5f0a89b71e29173986664694587a648 1294 Pfam PF00550 Phosphopantetheine attachment site 521 582 1.9E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS14515 c5f0a89b71e29173986664694587a648 1294 SUPERFAMILY SSF51161 1180 1294 1.52E-17 T 28-03-2018 IPR011004 Trimeric LpxA-like CU254_RS14515 c5f0a89b71e29173986664694587a648 1294 Gene3D G3DSA:3.30.300.30 408 523 2.0E-25 T 28-03-2018 CU254_RS14515 c5f0a89b71e29173986664694587a648 1294 Gene3D G3DSA:3.40.50.980 168 324 2.8E-34 T 28-03-2018 CU254_RS14515 c5f0a89b71e29173986664694587a648 1294 ProSitePatterns PS00455 Putative AMP-binding domain signature. 162 173 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS14515 c5f0a89b71e29173986664694587a648 1294 Gene3D G3DSA:1.10.1200.10 524 605 7.5E-15 T 28-03-2018 CU254_RS14515 c5f0a89b71e29173986664694587a648 1294 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 60 436 5.0E-99 T 28-03-2018 IPR010071 Amino acid adenylation domain CU254_RS14515 c5f0a89b71e29173986664694587a648 1294 SUPERFAMILY SSF51161 723 823 5.68E-14 T 28-03-2018 IPR011004 Trimeric LpxA-like CU254_RS14515 c5f0a89b71e29173986664694587a648 1294 SMART SM00823 Phosphopantetheine attachment site 519 586 3.1E-6 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS14515 c5f0a89b71e29173986664694587a648 1294 Pfam PF00501 AMP-binding enzyme 39 412 3.3E-66 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS14515 c5f0a89b71e29173986664694587a648 1294 Gene3D G3DSA:3.40.50.980 30 167 2.6E-36 T 28-03-2018 CU254_RS14515 c5f0a89b71e29173986664694587a648 1294 SUPERFAMILY SSF47336 512 582 7.72E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS14515 c5f0a89b71e29173986664694587a648 1294 Gene3D G3DSA:2.160.10.10 947 1057 3.8E-8 T 28-03-2018 CU254_RS14515 c5f0a89b71e29173986664694587a648 1294 Gene3D G3DSA:2.160.10.10 696 819 3.6E-14 T 28-03-2018 CU254_RS14515 c5f0a89b71e29173986664694587a648 1294 SUPERFAMILY SSF56801 28 531 2.22E-114 T 28-03-2018 CU254_RS20545 84560fe35beec1e3fd79b3406501632a 563 Gene3D G3DSA:2.30.38.10 369 456 5.9E-25 T 28-03-2018 CU254_RS20545 84560fe35beec1e3fd79b3406501632a 563 ProSitePatterns PS00455 Putative AMP-binding domain signature. 204 215 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS20545 84560fe35beec1e3fd79b3406501632a 563 Gene3D G3DSA:3.40.50.980 32 210 1.8E-44 T 28-03-2018 CU254_RS20545 84560fe35beec1e3fd79b3406501632a 563 Pfam PF13193 AMP-binding enzyme C-terminal domain 472 546 2.0E-15 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS20545 84560fe35beec1e3fd79b3406501632a 563 Pfam PF00501 AMP-binding enzyme 41 463 1.6E-94 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS20545 84560fe35beec1e3fd79b3406501632a 563 Gene3D G3DSA:3.40.50.980 211 368 7.4E-30 T 28-03-2018 CU254_RS20545 84560fe35beec1e3fd79b3406501632a 563 SUPERFAMILY SSF56801 29 558 7.2E-136 T 28-03-2018 CU254_RS20545 84560fe35beec1e3fd79b3406501632a 563 Gene3D G3DSA:3.30.300.30 458 563 1.1E-25 T 28-03-2018 CU254_RS06350 3bfaef4b492c70df5562605a1835b722 395 ProSitePatterns PS00737 Thiolases signature 2. 339 355 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CU254_RS06350 3bfaef4b492c70df5562605a1835b722 395 Gene3D G3DSA:3.40.47.10 266 390 5.1E-34 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS06350 3bfaef4b492c70df5562605a1835b722 395 SUPERFAMILY SSF53901 5 270 1.71E-85 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS06350 3bfaef4b492c70df5562605a1835b722 395 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 390 6.8E-137 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CU254_RS06350 3bfaef4b492c70df5562605a1835b722 395 ProSitePatterns PS00099 Thiolases active site. 374 387 - T 28-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CU254_RS06350 3bfaef4b492c70df5562605a1835b722 395 PIRSF PIRSF000429 3 394 2.4E-120 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CU254_RS06350 3bfaef4b492c70df5562605a1835b722 395 Gene3D G3DSA:3.40.47.10 2 184 8.5E-38 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS06350 3bfaef4b492c70df5562605a1835b722 395 Gene3D G3DSA:3.40.47.10 185 265 2.2E-24 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS06350 3bfaef4b492c70df5562605a1835b722 395 Pfam PF00108 Thiolase, N-terminal domain 5 261 1.8E-97 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CU254_RS06350 3bfaef4b492c70df5562605a1835b722 395 SUPERFAMILY SSF53901 271 391 7.82E-38 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS06350 3bfaef4b492c70df5562605a1835b722 395 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 84 102 - T 28-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 CU254_RS06350 3bfaef4b492c70df5562605a1835b722 395 Pfam PF02803 Thiolase, C-terminal domain 271 391 4.6E-44 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CU254_RS34495 b80edd04065caf80a67e5eb4a1999319 400 Pfam PF14759 Reductase C-terminal 322 392 6.9E-16 T 28-03-2018 IPR028202 Reductase, C-terminal CU254_RS34495 b80edd04065caf80a67e5eb4a1999319 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 2.2E-16 T 28-03-2018 CU254_RS34495 b80edd04065caf80a67e5eb4a1999319 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 228 244 2.2E-16 T 28-03-2018 CU254_RS34495 b80edd04065caf80a67e5eb4a1999319 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 98 116 2.2E-16 T 28-03-2018 CU254_RS34495 b80edd04065caf80a67e5eb4a1999319 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 142 160 2.2E-16 T 28-03-2018 CU254_RS34495 b80edd04065caf80a67e5eb4a1999319 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 255 277 2.2E-16 T 28-03-2018 CU254_RS34495 b80edd04065caf80a67e5eb4a1999319 400 SUPERFAMILY SSF51905 138 310 5.01E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS34495 b80edd04065caf80a67e5eb4a1999319 400 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 142 167 1.4E-13 T 28-03-2018 CU254_RS34495 b80edd04065caf80a67e5eb4a1999319 400 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 270 277 1.4E-13 T 28-03-2018 CU254_RS34495 b80edd04065caf80a67e5eb4a1999319 400 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 1.4E-13 T 28-03-2018 CU254_RS34495 b80edd04065caf80a67e5eb4a1999319 400 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 229 243 1.4E-13 T 28-03-2018 CU254_RS34495 b80edd04065caf80a67e5eb4a1999319 400 SUPERFAMILY SSF55424 316 391 3.85E-19 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CU254_RS34495 b80edd04065caf80a67e5eb4a1999319 400 Gene3D G3DSA:3.50.50.60 241 319 0.002 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS34495 b80edd04065caf80a67e5eb4a1999319 400 SUPERFAMILY SSF51905 2 186 2.02E-34 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS34495 b80edd04065caf80a67e5eb4a1999319 400 Gene3D G3DSA:3.50.50.60 2 96 4.7E-12 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS34495 b80edd04065caf80a67e5eb4a1999319 400 Gene3D G3DSA:3.50.50.60 97 233 4.2E-27 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS34495 b80edd04065caf80a67e5eb4a1999319 400 Gene3D G3DSA:3.30.390.30 320 399 3.8E-22 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CU254_RS34495 b80edd04065caf80a67e5eb4a1999319 400 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 301 5.2E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS33390 8a3ba62c315f17b3f4f2e5e14011b019 368 SUPERFAMILY SSF54826 2 124 6.48E-28 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CU254_RS33390 8a3ba62c315f17b3f4f2e5e14011b019 368 Hamap MF_01933 o-succinylbenzoate synthase [menC]. 1 359 41.004 T 28-03-2018 IPR010197 o-Succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00010+4.2.1.11|KEGG: 00130+4.2.1.113|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-5837|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CU254_RS33390 8a3ba62c315f17b3f4f2e5e14011b019 368 Gene3D G3DSA:3.20.20.120 133 348 8.5E-58 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CU254_RS33390 8a3ba62c315f17b3f4f2e5e14011b019 368 SMART SM00922 142 235 1.1E-19 T 28-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CU254_RS33390 8a3ba62c315f17b3f4f2e5e14011b019 368 TIGRFAM TIGR01928 menC_lowGC/arch: o-succinylbenzoate synthase 10 331 2.9E-91 T 28-03-2018 IPR010197 o-Succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00010+4.2.1.11|KEGG: 00130+4.2.1.113|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-5837|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CU254_RS33390 8a3ba62c315f17b3f4f2e5e14011b019 368 Pfam PF13378 Enolase C-terminal domain-like 152 351 7.3E-48 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CU254_RS33390 8a3ba62c315f17b3f4f2e5e14011b019 368 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 8 121 3.0E-9 T 28-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CU254_RS33390 8a3ba62c315f17b3f4f2e5e14011b019 368 SUPERFAMILY SSF51604 123 358 6.16E-66 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CU254_RS33390 8a3ba62c315f17b3f4f2e5e14011b019 368 Gene3D G3DSA:3.30.390.10 2 132 1.9E-31 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CU254_RS01010 4fec6f926fbd4ed4169709c1ff844696 420 Pfam PF00534 Glycosyl transferases group 1 208 382 1.6E-31 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CU254_RS01010 4fec6f926fbd4ed4169709c1ff844696 420 SUPERFAMILY SSF53756 18 404 1.05E-82 T 28-03-2018 CU254_RS01010 4fec6f926fbd4ed4169709c1ff844696 420 Gene3D G3DSA:3.40.50.2000 210 385 1.2E-46 T 28-03-2018 CU254_RS01010 4fec6f926fbd4ed4169709c1ff844696 420 TIGRFAM TIGR03449 mycothiol_MshA: D-inositol-3-phosphate glycosyltransferase 1 405 1.1E-191 T 28-03-2018 IPR017814 Mycothiol biosynthesis protein, MshA GO:0008375|GO:0010125 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 CU254_RS01010 4fec6f926fbd4ed4169709c1ff844696 420 Gene3D G3DSA:3.40.50.2000 15 209 2.3E-21 T 28-03-2018 CU254_RS01010 4fec6f926fbd4ed4169709c1ff844696 420 Pfam PF13439 Glycosyltransferase Family 4 19 200 9.2E-32 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CU254_RS01010 4fec6f926fbd4ed4169709c1ff844696 420 Hamap MF_01695 D-inositol-3-phosphate glycosyltransferase [mshA]. 1 409 50.381 T 28-03-2018 IPR017814 Mycothiol biosynthesis protein, MshA GO:0008375|GO:0010125 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 CU254_RS28225 735ed8c46e803eaf2500a9cac5bd766b 592 Pfam PF04294 VanW like protein 385 516 9.0E-41 T 28-03-2018 IPR007391 Vancomycin resistance VanW CU254_RS28225 735ed8c46e803eaf2500a9cac5bd766b 592 Pfam PF12229 Putative peptidoglycan binding domain 251 345 7.9E-11 T 28-03-2018 IPR022029 Putative peptidoglycan binding domain CU254_RS26525 b66764dd4b0fda526a76f663aa4aebd4 356 SMART SM00304 69 121 1.8E-15 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS26525 b66764dd4b0fda526a76f663aa4aebd4 356 Pfam PF00512 His Kinase A (phospho-acceptor) domain 123 186 1.6E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS26525 b66764dd4b0fda526a76f663aa4aebd4 356 SMART SM00387 234 356 1.0E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS26525 b66764dd4b0fda526a76f663aa4aebd4 356 PRINTS PR00344 Bacterial sensor protein C-terminal signature 271 285 1.1E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS26525 b66764dd4b0fda526a76f663aa4aebd4 356 PRINTS PR00344 Bacterial sensor protein C-terminal signature 289 299 1.1E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS26525 b66764dd4b0fda526a76f663aa4aebd4 356 PRINTS PR00344 Bacterial sensor protein C-terminal signature 303 321 1.1E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS26525 b66764dd4b0fda526a76f663aa4aebd4 356 Gene3D G3DSA:1.10.287.130 112 168 4.5E-16 T 28-03-2018 CU254_RS26525 b66764dd4b0fda526a76f663aa4aebd4 356 SUPERFAMILY SSF47384 105 187 2.94E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS26525 b66764dd4b0fda526a76f663aa4aebd4 356 Pfam PF00672 HAMP domain 71 116 1.1E-14 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS26525 b66764dd4b0fda526a76f663aa4aebd4 356 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 235 355 2.6E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS26525 b66764dd4b0fda526a76f663aa4aebd4 356 SMART SM00388 122 186 7.3E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS26525 b66764dd4b0fda526a76f663aa4aebd4 356 Gene3D G3DSA:3.30.565.10 169 356 2.3E-49 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS26525 b66764dd4b0fda526a76f663aa4aebd4 356 SUPERFAMILY SSF158472 71 117 1.44E-11 T 28-03-2018 CU254_RS26525 b66764dd4b0fda526a76f663aa4aebd4 356 SUPERFAMILY SSF55874 176 331 4.71E-40 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS41055 d58dea71c17ae798c7d724ea842ae1be 571 Gene3D G3DSA:3.30.200.20 277 367 2.8E-8 T 28-03-2018 CU254_RS41055 d58dea71c17ae798c7d724ea842ae1be 571 Gene3D G3DSA:3.40.50.300 1 204 2.5E-18 T 28-03-2018 CU254_RS41055 d58dea71c17ae798c7d724ea842ae1be 571 SUPERFAMILY SSF56112 294 542 5.1E-21 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS41055 d58dea71c17ae798c7d724ea842ae1be 571 Hamap MF_00165 Thymidylate kinase [tmk]. 1 218 13.171 T 28-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CU254_RS41055 d58dea71c17ae798c7d724ea842ae1be 571 SUPERFAMILY SSF52540 2 211 5.09E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS41055 d58dea71c17ae798c7d724ea842ae1be 571 Gene3D G3DSA:3.90.1200.10 376 569 2.2E-5 T 28-03-2018 CU254_RS41055 d58dea71c17ae798c7d724ea842ae1be 571 Pfam PF02223 Thymidylate kinase 5 199 2.1E-6 T 28-03-2018 CU254_RS09865 b049406740a70b348bd9373dac782a5b 326 SUPERFAMILY SSF51735 9 323 4.0E-88 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS09865 b049406740a70b348bd9373dac782a5b 326 Gene3D G3DSA:3.40.50.720 9 174 1.0E-30 T 28-03-2018 CU254_RS09865 b049406740a70b348bd9373dac782a5b 326 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 9 324 1.0E-110 T 28-03-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-70370 CU254_RS09865 b049406740a70b348bd9373dac782a5b 326 Pfam PF01370 NAD dependent epimerase/dehydratase family 11 253 8.1E-56 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CU254_RS09865 b049406740a70b348bd9373dac782a5b 326 Gene3D G3DSA:3.90.25.10 175 326 7.2E-38 T 28-03-2018 CU254_RS36285 4891e12f3b238980facf30e3505dc981 300 Gene3D G3DSA:1.10.1040.20 175 272 4.2E-37 T 28-03-2018 IPR018931 Domain of unknown function DUF2520 CU254_RS36285 4891e12f3b238980facf30e3505dc981 300 Pfam PF10727 Rossmann-like domain 2 123 3.9E-47 T 28-03-2018 IPR019665 Putative oxidoreductase/dehydrogenase, Rossmann-like domain CU254_RS36285 4891e12f3b238980facf30e3505dc981 300 SUPERFAMILY SSF51735 9 173 2.13E-24 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS36285 4891e12f3b238980facf30e3505dc981 300 Gene3D G3DSA:3.40.50.720 5 174 1.5E-18 T 28-03-2018 CU254_RS36285 4891e12f3b238980facf30e3505dc981 300 SUPERFAMILY SSF48179 176 274 2.82E-25 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CU254_RS36285 4891e12f3b238980facf30e3505dc981 300 Pfam PF10728 Domain of unknown function (DUF2520) 144 269 4.8E-39 T 28-03-2018 IPR018931 Domain of unknown function DUF2520 CU254_RS12595 ff516053aa89ee73ec80affe6678a77d 143 SUPERFAMILY SSF53067 9 120 1.91E-12 T 28-03-2018 CU254_RS12595 ff516053aa89ee73ec80affe6678a77d 143 Pfam PF00480 ROK family 10 117 7.0E-9 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CU254_RS12595 ff516053aa89ee73ec80affe6678a77d 143 Gene3D G3DSA:3.30.420.40 4 122 2.6E-13 T 28-03-2018 CU254_RS26430 241d9ce03adfd1f3543bf91ff38b60a6 299 Pfam PF07650 KH domain 209 288 2.5E-18 T 28-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS26430 241d9ce03adfd1f3543bf91ff38b60a6 299 TIGRFAM TIGR00436 era: GTP-binding protein Era 8 282 1.9E-70 T 28-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS26430 241d9ce03adfd1f3543bf91ff38b60a6 299 Gene3D G3DSA:3.30.300.20 186 299 1.4E-42 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CU254_RS26430 241d9ce03adfd1f3543bf91ff38b60a6 299 Pfam PF01926 50S ribosome-binding GTPase 10 126 4.7E-21 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CU254_RS26430 241d9ce03adfd1f3543bf91ff38b60a6 299 Gene3D G3DSA:3.40.50.300 5 24 0.13 T 28-03-2018 CU254_RS26430 241d9ce03adfd1f3543bf91ff38b60a6 299 Gene3D G3DSA:3.40.50.300 25 179 2.9E-34 T 28-03-2018 CU254_RS26430 241d9ce03adfd1f3543bf91ff38b60a6 299 Hamap MF_00367 GTPase Era [era]. 5 299 34.772 T 28-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS26430 241d9ce03adfd1f3543bf91ff38b60a6 299 SUPERFAMILY SSF54814 184 299 1.24E-35 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CU254_RS26430 241d9ce03adfd1f3543bf91ff38b60a6 299 SUPERFAMILY SSF52540 11 218 6.04E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS26430 241d9ce03adfd1f3543bf91ff38b60a6 299 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 12 169 1.7E-20 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CU254_RS12940 3d465f31135c0d05dece9c619b9c68f3 332 Gene3D G3DSA:3.40.50.1980 40 167 5.7E-24 T 28-03-2018 CU254_RS12940 3d465f31135c0d05dece9c619b9c68f3 332 SUPERFAMILY SSF53807 47 326 1.02E-37 T 28-03-2018 CU254_RS12940 3d465f31135c0d05dece9c619b9c68f3 332 Pfam PF01497 Periplasmic binding protein 64 295 8.3E-18 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CU254_RS12940 3d465f31135c0d05dece9c619b9c68f3 332 Gene3D G3DSA:3.40.50.1980 168 331 9.6E-22 T 28-03-2018 CU254_RS34210 fdda67dee9ea1fc3b4fa987152eecaf1 209 SUPERFAMILY SSF53335 55 202 7.54E-18 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS34210 fdda67dee9ea1fc3b4fa987152eecaf1 209 Pfam PF13489 Methyltransferase domain 54 193 5.4E-10 T 28-03-2018 CU254_RS34210 fdda67dee9ea1fc3b4fa987152eecaf1 209 Gene3D G3DSA:3.40.50.150 34 209 2.4E-16 T 28-03-2018 CU254_RS27425 4c8dee2fb90bb92679ee8c9a72799f13 319 Gene3D G3DSA:2.40.30.10 5 105 2.4E-17 T 28-03-2018 CU254_RS27425 4c8dee2fb90bb92679ee8c9a72799f13 319 Gene3D G3DSA:3.40.50.80 106 218 2.5E-17 T 28-03-2018 CU254_RS27425 4c8dee2fb90bb92679ee8c9a72799f13 319 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 268 276 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CU254_RS27425 4c8dee2fb90bb92679ee8c9a72799f13 319 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 241 310 4.5E-9 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CU254_RS27425 4c8dee2fb90bb92679ee8c9a72799f13 319 SUPERFAMILY SSF63380 8 105 9.85E-27 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CU254_RS27425 4c8dee2fb90bb92679ee8c9a72799f13 319 SUPERFAMILY SSF54292 211 317 5.11E-24 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CU254_RS27425 4c8dee2fb90bb92679ee8c9a72799f13 319 SUPERFAMILY SSF52343 103 224 4.19E-25 T 28-03-2018 CU254_RS27425 4c8dee2fb90bb92679ee8c9a72799f13 319 PRINTS PR00409 Phthalate dioxygenase reductase family signature 35 45 1.3E-31 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CU254_RS27425 4c8dee2fb90bb92679ee8c9a72799f13 319 PRINTS PR00409 Phthalate dioxygenase reductase family signature 45 57 1.3E-31 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CU254_RS27425 4c8dee2fb90bb92679ee8c9a72799f13 319 PRINTS PR00409 Phthalate dioxygenase reductase family signature 57 71 1.3E-31 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CU254_RS27425 4c8dee2fb90bb92679ee8c9a72799f13 319 PRINTS PR00409 Phthalate dioxygenase reductase family signature 116 135 1.3E-31 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CU254_RS27425 4c8dee2fb90bb92679ee8c9a72799f13 319 PRINTS PR00409 Phthalate dioxygenase reductase family signature 141 150 1.3E-31 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CU254_RS27425 4c8dee2fb90bb92679ee8c9a72799f13 319 PRINTS PR00409 Phthalate dioxygenase reductase family signature 81 95 1.3E-31 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CU254_RS27425 4c8dee2fb90bb92679ee8c9a72799f13 319 PRINTS PR00409 Phthalate dioxygenase reductase family signature 191 199 1.3E-31 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CU254_RS27425 4c8dee2fb90bb92679ee8c9a72799f13 319 Gene3D G3DSA:3.10.20.30 219 319 2.7E-17 T 28-03-2018 IPR012675 Beta-grasp domain CU254_RS10195 67d9040fd1a9549d5eb644c6b4dcf19d 383 PIRSF PIRSF016578 5 367 5.0E-15 T 28-03-2018 CU254_RS10195 67d9040fd1a9549d5eb644c6b4dcf19d 383 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 235 382 4.0E-42 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS10195 67d9040fd1a9549d5eb644c6b4dcf19d 383 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 12 123 1.1E-31 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS10195 67d9040fd1a9549d5eb644c6b4dcf19d 383 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 127 222 4.3E-28 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CU254_RS10195 67d9040fd1a9549d5eb644c6b4dcf19d 383 Gene3D G3DSA:1.20.140.10 225 383 4.1E-50 T 28-03-2018 CU254_RS10195 67d9040fd1a9549d5eb644c6b4dcf19d 383 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 342 361 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CU254_RS10195 67d9040fd1a9549d5eb644c6b4dcf19d 383 Gene3D G3DSA:2.40.110.10 126 224 2.9E-41 T 28-03-2018 CU254_RS10195 67d9040fd1a9549d5eb644c6b4dcf19d 383 Gene3D G3DSA:1.10.540.10 3 125 5.0E-33 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS10195 67d9040fd1a9549d5eb644c6b4dcf19d 383 SUPERFAMILY SSF56645 9 247 1.96E-85 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS10195 67d9040fd1a9549d5eb644c6b4dcf19d 383 SUPERFAMILY SSF47203 234 383 3.22E-47 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS11505 330eda854cbf484ff50fcf7f966ba2b3 223 Gene3D G3DSA:3.30.63.10 71 103 4.2E-25 T 28-03-2018 CU254_RS11505 330eda854cbf484ff50fcf7f966ba2b3 223 Gene3D G3DSA:3.40.50.300 24 70 0.003 T 28-03-2018 CU254_RS11505 330eda854cbf484ff50fcf7f966ba2b3 223 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 29 205 2.4E-66 T 28-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 CU254_RS11505 330eda854cbf484ff50fcf7f966ba2b3 223 Pfam PF00625 Guanylate kinase 29 205 3.2E-42 T 28-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit CU254_RS11505 330eda854cbf484ff50fcf7f966ba2b3 223 Gene3D G3DSA:3.40.50.300 104 207 5.3E-27 T 28-03-2018 CU254_RS11505 330eda854cbf484ff50fcf7f966ba2b3 223 SUPERFAMILY SSF52540 27 206 1.29E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS11505 330eda854cbf484ff50fcf7f966ba2b3 223 SMART SM00072 27 209 1.7E-62 T 28-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit CU254_RS11505 330eda854cbf484ff50fcf7f966ba2b3 223 Hamap MF_00328 Guanylate kinase [gmk]. 26 209 34.445 T 28-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 CU254_RS11505 330eda854cbf484ff50fcf7f966ba2b3 223 ProSitePatterns PS00856 Guanylate kinase-like signature. 62 79 - T 28-03-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 CU254_RS02370 63a950497194dec50d676d0b4c806ba4 97 Pfam PF00166 Chaperonin 10 Kd subunit 4 96 1.7E-35 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CU254_RS02370 63a950497194dec50d676d0b4c806ba4 97 ProSitePatterns PS00681 Chaperonins cpn10 signature. 5 29 - T 28-03-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 CU254_RS02370 63a950497194dec50d676d0b4c806ba4 97 Gene3D G3DSA:2.30.33.40 1 97 2.0E-39 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CU254_RS02370 63a950497194dec50d676d0b4c806ba4 97 PRINTS PR00297 10kDa chaperonin signature 5 20 1.9E-30 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CU254_RS02370 63a950497194dec50d676d0b4c806ba4 97 PRINTS PR00297 10kDa chaperonin signature 62 74 1.9E-30 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CU254_RS02370 63a950497194dec50d676d0b4c806ba4 97 PRINTS PR00297 10kDa chaperonin signature 83 96 1.9E-30 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CU254_RS02370 63a950497194dec50d676d0b4c806ba4 97 PRINTS PR00297 10kDa chaperonin signature 27 48 1.9E-30 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CU254_RS02370 63a950497194dec50d676d0b4c806ba4 97 SUPERFAMILY SSF50129 3 97 9.42E-35 T 28-03-2018 IPR011032 GroES-like CU254_RS02370 63a950497194dec50d676d0b4c806ba4 97 SMART SM00883 4 96 6.0E-54 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CU254_RS02370 63a950497194dec50d676d0b4c806ba4 97 Hamap MF_00580 10 kDa chaperonin [groS]. 4 97 26.075 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CU254_RS24805 e863a7944d10da5ab5e34ee3fc5e1f7e 503 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 148 160 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CU254_RS24805 e863a7944d10da5ab5e34ee3fc5e1f7e 503 SMART SM00220 25 280 1.1E-57 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CU254_RS24805 e863a7944d10da5ab5e34ee3fc5e1f7e 503 SUPERFAMILY SSF56112 21 282 5.4E-68 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS24805 e863a7944d10da5ab5e34ee3fc5e1f7e 503 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 31 54 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 CU254_RS24805 e863a7944d10da5ab5e34ee3fc5e1f7e 503 Gene3D G3DSA:1.10.510.10 113 466 6.8E-45 T 28-03-2018 CU254_RS24805 e863a7944d10da5ab5e34ee3fc5e1f7e 503 Pfam PF00069 Protein kinase domain 28 275 9.0E-49 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CU254_RS24805 e863a7944d10da5ab5e34ee3fc5e1f7e 503 Gene3D G3DSA:3.30.200.20 2 112 9.9E-22 T 28-03-2018 CU254_RS21995 df7a09a58e5938dc2686fd206bb690e8 568 PIRSF PIRSF006337 1 566 3.5E-221 T 28-03-2018 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00500+3.2.1.141|KEGG: 00520+3.2.1.14|MetaCyc: PWY-2661|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 CU254_RS21995 df7a09a58e5938dc2686fd206bb690e8 568 SUPERFAMILY SSF51445 70 498 1.56E-107 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS21995 df7a09a58e5938dc2686fd206bb690e8 568 Gene3D G3DSA:1.10.10.760 424 461 1.1E-15 T 28-03-2018 CU254_RS21995 df7a09a58e5938dc2686fd206bb690e8 568 Gene3D G3DSA:2.60.40.1180 514 567 1.3E-4 T 28-03-2018 CU254_RS21995 df7a09a58e5938dc2686fd206bb690e8 568 TIGRFAM TIGR02402 trehalose_TreZ: malto-oligosyltrehalose trehalohydrolase 2 537 4.5E-223 T 28-03-2018 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00500+3.2.1.141|KEGG: 00520+3.2.1.14|MetaCyc: PWY-2661|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 CU254_RS21995 df7a09a58e5938dc2686fd206bb690e8 568 Gene3D G3DSA:3.20.20.80 82 423 2.2E-60 T 28-03-2018 CU254_RS21995 df7a09a58e5938dc2686fd206bb690e8 568 Pfam PF00128 Alpha amylase, catalytic domain 105 190 7.7E-12 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CU254_RS21995 df7a09a58e5938dc2686fd206bb690e8 568 SUPERFAMILY SSF81296 2 73 1.0E-14 T 28-03-2018 IPR014756 Immunoglobulin E-set CU254_RS21995 df7a09a58e5938dc2686fd206bb690e8 568 SMART SM00642 95 445 2.7E-8 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CU254_RS21995 df7a09a58e5938dc2686fd206bb690e8 568 Pfam PF11941 Domain of unknown function (DUF3459) 483 564 5.4E-20 T 28-03-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) CU254_RS21995 df7a09a58e5938dc2686fd206bb690e8 568 Gene3D G3DSA:2.60.40.10 1 79 1.2E-17 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS25345 7d3daf0922015336e9c6ff70abcdfaa9 165 ProSitePatterns PS01117 MarR-type HTH domain signature. 86 120 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CU254_RS25345 7d3daf0922015336e9c6ff70abcdfaa9 165 SMART SM00347 44 147 8.7E-24 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS25345 7d3daf0922015336e9c6ff70abcdfaa9 165 Pfam PF01047 MarR family 51 111 3.3E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS25345 7d3daf0922015336e9c6ff70abcdfaa9 165 Gene3D G3DSA:1.10.10.10 1 164 2.0E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS25345 7d3daf0922015336e9c6ff70abcdfaa9 165 SUPERFAMILY SSF46785 13 161 2.9E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS25345 7d3daf0922015336e9c6ff70abcdfaa9 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 137 157 4.1E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS25345 7d3daf0922015336e9c6ff70abcdfaa9 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 107 123 4.1E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS25345 7d3daf0922015336e9c6ff70abcdfaa9 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 103 4.1E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS25345 7d3daf0922015336e9c6ff70abcdfaa9 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 71 87 4.1E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS14960 c661599944baa6cc9dce10c2d34cb50f 425 Gene3D G3DSA:3.90.1150.10 165 269 0.037 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS14960 c661599944baa6cc9dce10c2d34cb50f 425 Gene3D G3DSA:3.90.1150.10 2 164 3.0E-39 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS14960 c661599944baa6cc9dce10c2d34cb50f 425 PIRSF PIRSF000521 19 423 3.9E-31 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CU254_RS14960 c661599944baa6cc9dce10c2d34cb50f 425 Pfam PF00202 Aminotransferase class-III 26 416 4.2E-97 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CU254_RS14960 c661599944baa6cc9dce10c2d34cb50f 425 Gene3D G3DSA:3.90.1150.10 270 424 5.4E-49 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS14960 c661599944baa6cc9dce10c2d34cb50f 425 SUPERFAMILY SSF53383 15 419 5.41E-122 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS14960 c661599944baa6cc9dce10c2d34cb50f 425 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 245 282 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CU254_RS20420 7f9f2d61341207bee5d7829bbf66d646 225 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 74 8.1E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS20420 7f9f2d61341207bee5d7829bbf66d646 225 SUPERFAMILY SSF48008 82 201 2.38E-11 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS20420 7f9f2d61341207bee5d7829bbf66d646 225 Gene3D G3DSA:1.10.10.10 2 76 2.1E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS20420 7f9f2d61341207bee5d7829bbf66d646 225 SUPERFAMILY SSF46785 14 78 2.06E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS20420 7f9f2d61341207bee5d7829bbf66d646 225 SMART SM00345 16 74 7.3E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS20420 7f9f2d61341207bee5d7829bbf66d646 225 Pfam PF07729 FCD domain 88 195 3.4E-8 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS20420 7f9f2d61341207bee5d7829bbf66d646 225 SMART SM00895 84 204 1.1E-4 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS20420 7f9f2d61341207bee5d7829bbf66d646 225 Gene3D G3DSA:1.20.120.530 77 219 6.2E-13 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS01355 c3094d3551bd8df965dcad12bcfa7ead 443 Gene3D G3DSA:1.10.645.10 39 225 7.1E-48 T 28-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS01355 c3094d3551bd8df965dcad12bcfa7ead 443 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 35 443 45.723 T 28-03-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS01355 c3094d3551bd8df965dcad12bcfa7ead 443 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 43 443 1.4E-162 T 28-03-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS01355 c3094d3551bd8df965dcad12bcfa7ead 443 Gene3D G3DSA:1.10.645.10 226 439 2.2E-38 T 28-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS01355 c3094d3551bd8df965dcad12bcfa7ead 443 SUPERFAMILY SSF56762 53 443 8.5E-119 T 28-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS01355 c3094d3551bd8df965dcad12bcfa7ead 443 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 157 443 3.5E-108 T 28-03-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS30175 e26a2d68843b276dfb599d88f7e89fa4 498 SUPERFAMILY SSF56801 8 491 2.49E-96 T 28-03-2018 CU254_RS30175 e26a2d68843b276dfb599d88f7e89fa4 498 Gene3D G3DSA:3.40.50.980 157 316 9.4E-32 T 28-03-2018 CU254_RS30175 e26a2d68843b276dfb599d88f7e89fa4 498 Gene3D G3DSA:3.40.50.980 4 156 2.5E-33 T 28-03-2018 CU254_RS30175 e26a2d68843b276dfb599d88f7e89fa4 498 Gene3D G3DSA:3.30.300.30 397 493 3.6E-16 T 28-03-2018 CU254_RS30175 e26a2d68843b276dfb599d88f7e89fa4 498 Pfam PF00501 AMP-binding enzyme 19 401 5.9E-60 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS30175 e26a2d68843b276dfb599d88f7e89fa4 498 Gene3D G3DSA:2.30.38.10 321 392 2.8E-11 T 28-03-2018 CU254_RS30175 e26a2d68843b276dfb599d88f7e89fa4 498 ProSitePatterns PS00455 Putative AMP-binding domain signature. 151 162 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS18895 4dbfdc718da758fb1e8645ede8672cae 494 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 263 270 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CU254_RS18895 4dbfdc718da758fb1e8645ede8672cae 494 SUPERFAMILY SSF53720 32 462 3.14E-122 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CU254_RS18895 4dbfdc718da758fb1e8645ede8672cae 494 Gene3D G3DSA:3.40.309.10 383 443 5.8E-11 T 28-03-2018 CU254_RS18895 4dbfdc718da758fb1e8645ede8672cae 494 Gene3D G3DSA:3.40.309.10 279 382 2.0E-31 T 28-03-2018 CU254_RS18895 4dbfdc718da758fb1e8645ede8672cae 494 Pfam PF00171 Aldehyde dehydrogenase family 35 384 1.1E-101 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CU254_RS18895 4dbfdc718da758fb1e8645ede8672cae 494 Gene3D G3DSA:3.40.605.10 25 278 2.1E-76 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CU254_RS28875 eb85651a1433a3b58c5391d2cd494fab 330 Gene3D G3DSA:3.40.50.150 86 330 5.1E-41 T 28-03-2018 CU254_RS28875 eb85651a1433a3b58c5391d2cd494fab 330 SUPERFAMILY SSF46785 3 76 4.9E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS28875 eb85651a1433a3b58c5391d2cd494fab 330 Gene3D G3DSA:1.10.10.10 1 85 7.3E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS28875 eb85651a1433a3b58c5391d2cd494fab 330 PIRSF PIRSF005739 50 319 4.1E-26 T 28-03-2018 IPR016461 O-methyltransferase COMT-type GO:0008168 CU254_RS28875 eb85651a1433a3b58c5391d2cd494fab 330 Pfam PF16864 Dimerisation domain 2 82 2.6E-10 T 28-03-2018 IPR031725 Acetylserotonin O-methyltransferase, dimerisation domain CU254_RS28875 eb85651a1433a3b58c5391d2cd494fab 330 Pfam PF00891 O-methyltransferase 91 308 2.3E-42 T 28-03-2018 IPR001077 O-methyltransferase, family 2 GO:0008171 CU254_RS28875 eb85651a1433a3b58c5391d2cd494fab 330 SUPERFAMILY SSF53335 83 319 1.82E-44 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS38440 1658a57b8b97055ea8d3784812f5b638 614 SUPERFAMILY SSF47203 295 477 1.22E-29 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS38440 1658a57b8b97055ea8d3784812f5b638 614 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 162 275 1.4E-17 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CU254_RS38440 1658a57b8b97055ea8d3784812f5b638 614 SUPERFAMILY SSF56645 57 297 3.66E-41 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS38440 1658a57b8b97055ea8d3784812f5b638 614 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 477 610 2.8E-30 T 28-03-2018 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain CU254_RS38440 1658a57b8b97055ea8d3784812f5b638 614 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 3 25 1.4E-7 T 28-03-2018 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria CU254_RS38440 1658a57b8b97055ea8d3784812f5b638 614 Gene3D G3DSA:2.40.110.10 162 277 2.2E-23 T 28-03-2018 CU254_RS38440 1658a57b8b97055ea8d3784812f5b638 614 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 291 457 2.2E-13 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS38440 1658a57b8b97055ea8d3784812f5b638 614 Gene3D G3DSA:1.20.140.10 278 478 2.6E-30 T 28-03-2018 CU254_RS38440 1658a57b8b97055ea8d3784812f5b638 614 Gene3D G3DSA:1.10.540.10 31 161 1.2E-7 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS18255 facaf5182f1365d1364b4f8092d7df04 411 Pfam PF00756 Putative esterase 168 310 2.1E-18 T 28-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 CU254_RS18255 facaf5182f1365d1364b4f8092d7df04 411 SUPERFAMILY SSF53474 166 402 7.88E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS18255 facaf5182f1365d1364b4f8092d7df04 411 Gene3D G3DSA:3.40.50.1820 141 406 3.3E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS29375 5c73d0814f8c4db1a0400c50eadbc91d 252 Gene3D G3DSA:1.10.10.10 17 92 1.3E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS29375 5c73d0814f8c4db1a0400c50eadbc91d 252 SUPERFAMILY SSF48008 97 235 6.02E-17 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS29375 5c73d0814f8c4db1a0400c50eadbc91d 252 Gene3D G3DSA:1.20.120.530 93 245 6.0E-20 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS29375 5c73d0814f8c4db1a0400c50eadbc91d 252 SMART SM00345 33 91 2.4E-12 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS29375 5c73d0814f8c4db1a0400c50eadbc91d 252 Pfam PF07729 FCD domain 102 223 2.6E-13 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS29375 5c73d0814f8c4db1a0400c50eadbc91d 252 Pfam PF00392 Bacterial regulatory proteins, gntR family 30 91 4.3E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS29375 5c73d0814f8c4db1a0400c50eadbc91d 252 SMART SM00895 101 227 1.8E-7 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS29375 5c73d0814f8c4db1a0400c50eadbc91d 252 SUPERFAMILY SSF46785 26 95 7.87E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS08305 66ea61ab5aedd4e98327c411f67678a8 398 SUPERFAMILY SSF69055 305 396 9.81E-26 T 28-03-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CU254_RS08305 66ea61ab5aedd4e98327c411f67678a8 398 Pfam PF13288 DXP reductoisomerase C-terminal domain 274 391 4.1E-35 T 28-03-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CU254_RS08305 66ea61ab5aedd4e98327c411f67678a8 398 SUPERFAMILY SSF51735 5 162 7.88E-26 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS08305 66ea61ab5aedd4e98327c411f67678a8 398 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 7 396 41.856 T 28-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CU254_RS08305 66ea61ab5aedd4e98327c411f67678a8 398 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 158 241 9.0E-36 T 28-03-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CU254_RS08305 66ea61ab5aedd4e98327c411f67678a8 398 PIRSF PIRSF006205 4 398 2.4E-133 T 28-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CU254_RS08305 66ea61ab5aedd4e98327c411f67678a8 398 Gene3D G3DSA:3.40.50.720 3 162 1.8E-42 T 28-03-2018 CU254_RS08305 66ea61ab5aedd4e98327c411f67678a8 398 SUPERFAMILY SSF55347 140 276 3.6E-52 T 28-03-2018 CU254_RS08305 66ea61ab5aedd4e98327c411f67678a8 398 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 7 146 5.1E-33 T 28-03-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CU254_RS08305 66ea61ab5aedd4e98327c411f67678a8 398 Gene3D G3DSA:1.10.1740.10 315 398 4.6E-28 T 28-03-2018 CU254_RS08305 66ea61ab5aedd4e98327c411f67678a8 398 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 6 394 1.4E-109 T 28-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CU254_RS30570 ef69d934aa8fd7244567f9c9b854033b 233 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 232 3.9E-35 T 28-03-2018 CU254_RS30570 ef69d934aa8fd7244567f9c9b854033b 233 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 132 160 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS30570 ef69d934aa8fd7244567f9c9b854033b 233 SUPERFAMILY SSF51735 4 231 1.59E-52 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS30570 ef69d934aa8fd7244567f9c9b854033b 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 2.1E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS30570 ef69d934aa8fd7244567f9c9b854033b 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 164 2.1E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS30570 ef69d934aa8fd7244567f9c9b854033b 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 196 216 2.1E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS30570 ef69d934aa8fd7244567f9c9b854033b 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 2.1E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS30570 ef69d934aa8fd7244567f9c9b854033b 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 2.1E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS30570 ef69d934aa8fd7244567f9c9b854033b 233 Gene3D G3DSA:3.40.50.720 2 233 1.3E-46 T 28-03-2018 CU254_RS09905 05704f0aec0fb3d3fbbc2d210787a3bf 387 Gene3D G3DSA:2.40.110.10 125 219 1.5E-30 T 28-03-2018 CU254_RS09905 05704f0aec0fb3d3fbbc2d210787a3bf 387 Gene3D G3DSA:1.10.540.10 1 124 2.5E-27 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS09905 05704f0aec0fb3d3fbbc2d210787a3bf 387 SUPERFAMILY SSF56645 4 244 1.83E-64 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS09905 05704f0aec0fb3d3fbbc2d210787a3bf 387 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 126 209 1.5E-20 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CU254_RS09905 05704f0aec0fb3d3fbbc2d210787a3bf 387 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 380 7.2E-32 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS09905 05704f0aec0fb3d3fbbc2d210787a3bf 387 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 122 1.4E-21 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS09905 05704f0aec0fb3d3fbbc2d210787a3bf 387 Gene3D G3DSA:1.20.140.10 220 387 5.7E-31 T 28-03-2018 CU254_RS09905 05704f0aec0fb3d3fbbc2d210787a3bf 387 SUPERFAMILY SSF47203 231 384 4.19E-24 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS02620 c41aac6922ac6f296cfb9c04397825ac 170 Gene3D G3DSA:3.40.630.30 1 169 7.4E-23 T 28-03-2018 CU254_RS02620 c41aac6922ac6f296cfb9c04397825ac 170 Pfam PF13302 Acetyltransferase (GNAT) domain 6 143 1.1E-8 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS02620 c41aac6922ac6f296cfb9c04397825ac 170 SUPERFAMILY SSF55729 2 168 8.11E-27 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS28455 907b8972b5dfd276c353eb639aee03b1 322 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 315 90.131 T 28-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 CU254_RS28455 907b8972b5dfd276c353eb639aee03b1 322 Pfam PF03186 CobD/Cbib protein 12 293 1.4E-89 T 28-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 CU254_RS28455 907b8972b5dfd276c353eb639aee03b1 322 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 19 279 3.9E-52 T 28-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 CU254_RS31115 b9dfaf4ecce90bbce293b91c971e0e68 588 SUPERFAMILY SSF51735 4 185 2.6E-53 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS31115 b9dfaf4ecce90bbce293b91c971e0e68 588 SUPERFAMILY SSF48179 188 290 1.62E-29 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CU254_RS31115 b9dfaf4ecce90bbce293b91c971e0e68 588 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 492 588 2.6E-32 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CU254_RS31115 b9dfaf4ecce90bbce293b91c971e0e68 588 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 188 284 8.0E-31 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CU254_RS31115 b9dfaf4ecce90bbce293b91c971e0e68 588 Gene3D G3DSA:3.40.50.720 1 186 3.5E-53 T 28-03-2018 CU254_RS31115 b9dfaf4ecce90bbce293b91c971e0e68 588 Gene3D G3DSA:3.40.50.720 293 490 6.8E-50 T 28-03-2018 CU254_RS31115 b9dfaf4ecce90bbce293b91c971e0e68 588 SUPERFAMILY SSF48179 492 588 1.36E-28 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CU254_RS31115 b9dfaf4ecce90bbce293b91c971e0e68 588 SUPERFAMILY SSF51735 307 489 8.04E-51 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS31115 b9dfaf4ecce90bbce293b91c971e0e68 588 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 7 185 3.1E-60 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CU254_RS31115 b9dfaf4ecce90bbce293b91c971e0e68 588 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 312 489 1.1E-57 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CU254_RS31115 b9dfaf4ecce90bbce293b91c971e0e68 588 Gene3D G3DSA:1.10.1040.10 491 588 6.1E-31 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CU254_RS31115 b9dfaf4ecce90bbce293b91c971e0e68 588 Gene3D G3DSA:1.10.1040.10 187 289 1.3E-31 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CU254_RS02730 ccce9cdf8feb5c2e2a790cb555ce484a 407 Gene3D G3DSA:3.40.718.10 1 407 3.8E-132 T 28-03-2018 CU254_RS02730 ccce9cdf8feb5c2e2a790cb555ce484a 407 TIGRFAM TIGR00127 nadp_idh_euk: isocitrate dehydrogenase, NADP-dependent 3 405 2.2E-208 T 28-03-2018 IPR004790 Isocitrate dehydrogenase NADP-dependent GO:0004450|GO:0006102|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 CU254_RS02730 ccce9cdf8feb5c2e2a790cb555ce484a 407 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 10 392 1.4E-68 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CU254_RS02730 ccce9cdf8feb5c2e2a790cb555ce484a 407 SMART SM01329 9 396 2.8E-133 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CU254_RS02730 ccce9cdf8feb5c2e2a790cb555ce484a 407 PIRSF PIRSF000108 1 407 1.4E-221 T 28-03-2018 IPR004790 Isocitrate dehydrogenase NADP-dependent GO:0004450|GO:0006102|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 CU254_RS02730 ccce9cdf8feb5c2e2a790cb555ce484a 407 SUPERFAMILY SSF53659 1 404 1.38E-150 T 28-03-2018 CU254_RS02730 ccce9cdf8feb5c2e2a790cb555ce484a 407 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 271 290 - T 28-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 CU254_RS26070 ce151ca653c1fdd29b1b9aabf53237bb 349 SUPERFAMILY SSF51419 16 235 5.89E-22 T 28-03-2018 IPR029066 PLP-binding barrel CU254_RS26070 ce151ca653c1fdd29b1b9aabf53237bb 349 Gene3D G3DSA:3.20.20.10 16 246 2.8E-28 T 28-03-2018 IPR029066 PLP-binding barrel CU254_RS26070 ce151ca653c1fdd29b1b9aabf53237bb 349 Pfam PF01168 Alanine racemase, N-terminal domain 18 222 1.0E-13 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CU254_RS09175 ed90b14bfc727e5c608c7b12c8cd2dcd 369 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 18 367 3.1E-102 T 28-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CU254_RS09175 ed90b14bfc727e5c608c7b12c8cd2dcd 369 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 16 368 54.727 T 28-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CU254_RS09175 ed90b14bfc727e5c608c7b12c8cd2dcd 369 Gene3D G3DSA:3.40.640.10 49 261 1.7E-35 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS09175 ed90b14bfc727e5c608c7b12c8cd2dcd 369 Gene3D G3DSA:3.90.1150.10 262 368 1.1E-22 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS09175 ed90b14bfc727e5c608c7b12c8cd2dcd 369 Pfam PF00155 Aminotransferase class I and II 36 363 4.7E-57 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CU254_RS09175 ed90b14bfc727e5c608c7b12c8cd2dcd 369 SUPERFAMILY SSF53383 34 367 1.5E-72 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS09175 ed90b14bfc727e5c608c7b12c8cd2dcd 369 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 231 240 - T 28-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 CU254_RS11865 e10ba89fc1fbc7f3f87c8f3fe1cb785d 214 SUPERFAMILY SSF46894 140 210 3.3E-22 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS11865 e10ba89fc1fbc7f3f87c8f3fe1cb785d 214 Gene3D G3DSA:3.40.50.2300 2 128 4.3E-32 T 28-03-2018 CU254_RS11865 e10ba89fc1fbc7f3f87c8f3fe1cb785d 214 Pfam PF00072 Response regulator receiver domain 5 117 4.8E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS11865 e10ba89fc1fbc7f3f87c8f3fe1cb785d 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 4.3E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS11865 e10ba89fc1fbc7f3f87c8f3fe1cb785d 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 4.3E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS11865 e10ba89fc1fbc7f3f87c8f3fe1cb785d 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 4.3E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS11865 e10ba89fc1fbc7f3f87c8f3fe1cb785d 214 Gene3D G3DSA:1.10.10.10 129 214 2.4E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS11865 e10ba89fc1fbc7f3f87c8f3fe1cb785d 214 SMART SM00448 3 117 5.9E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS11865 e10ba89fc1fbc7f3f87c8f3fe1cb785d 214 SUPERFAMILY SSF52172 3 125 3.56E-29 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS11865 e10ba89fc1fbc7f3f87c8f3fe1cb785d 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 203 1.5E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS11865 e10ba89fc1fbc7f3f87c8f3fe1cb785d 214 SMART SM00421 147 204 1.3E-25 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS11865 e10ba89fc1fbc7f3f87c8f3fe1cb785d 214 ProSitePatterns PS00622 LuxR-type HTH domain signature. 164 191 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS40065 5fdf19418ce9c9c54cb4dbd117e04825 393 Pfam PF07730 Histidine kinase 193 259 1.6E-13 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CU254_RS40065 5fdf19418ce9c9c54cb4dbd117e04825 393 Gene3D G3DSA:3.30.565.10 215 393 2.3E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS40065 5fdf19418ce9c9c54cb4dbd117e04825 393 SUPERFAMILY SSF55781 7 179 3.93E-18 T 28-03-2018 IPR029016 GAF domain-like CU254_RS40065 5fdf19418ce9c9c54cb4dbd117e04825 393 Pfam PF13185 GAF domain 25 176 3.1E-12 T 28-03-2018 IPR003018 GAF domain GO:0005515 CU254_RS40065 5fdf19418ce9c9c54cb4dbd117e04825 393 Gene3D G3DSA:3.30.450.40 10 205 1.5E-25 T 28-03-2018 IPR029016 GAF domain-like CU254_RS40065 5fdf19418ce9c9c54cb4dbd117e04825 393 SUPERFAMILY SSF55874 261 392 5.37E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS40065 5fdf19418ce9c9c54cb4dbd117e04825 393 Pfam PF13581 Histidine kinase-like ATPase domain 299 372 2.1E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS40065 5fdf19418ce9c9c54cb4dbd117e04825 393 SMART SM00065 25 186 6.5E-6 T 28-03-2018 IPR003018 GAF domain GO:0005515 CU254_RS08965 98b5caae2c773bd0c1d53fec5a3fdcbb 428 Gene3D G3DSA:3.40.640.10 55 320 8.5E-76 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS08965 98b5caae2c773bd0c1d53fec5a3fdcbb 428 Gene3D G3DSA:3.90.1150.10 321 428 1.6E-22 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS08965 98b5caae2c773bd0c1d53fec5a3fdcbb 428 Hamap MF_00834 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [bioA]. 4 428 48.844 T 28-03-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 CU254_RS08965 98b5caae2c773bd0c1d53fec5a3fdcbb 428 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 16 424 2.6E-169 T 28-03-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 CU254_RS08965 98b5caae2c773bd0c1d53fec5a3fdcbb 428 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 246 283 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CU254_RS08965 98b5caae2c773bd0c1d53fec5a3fdcbb 428 Pfam PF00202 Aminotransferase class-III 25 423 1.4E-120 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CU254_RS08965 98b5caae2c773bd0c1d53fec5a3fdcbb 428 SUPERFAMILY SSF53383 7 425 3.06E-123 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS28375 1712873d6a7b9e04876720a389444f78 188 Gene3D G3DSA:1.10.357.10 67 188 5.8E-22 T 28-03-2018 CU254_RS28375 1712873d6a7b9e04876720a389444f78 188 SUPERFAMILY SSF46689 7 68 2.15E-19 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS28375 1712873d6a7b9e04876720a389444f78 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 9.6E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS28375 1712873d6a7b9e04876720a389444f78 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 9.6E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS28375 1712873d6a7b9e04876720a389444f78 188 SUPERFAMILY SSF48498 86 184 8.45E-18 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS28375 1712873d6a7b9e04876720a389444f78 188 Gene3D G3DSA:1.10.10.60 4 66 5.6E-24 T 28-03-2018 CU254_RS28375 1712873d6a7b9e04876720a389444f78 188 ProSitePatterns PS01081 TetR-type HTH domain signature. 31 61 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CU254_RS28375 1712873d6a7b9e04876720a389444f78 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 65 2.8E-21 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS26445 31ddb3ed43dc343e230f17c786e13046 183 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 36 148 6.6E-30 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CU254_RS26445 31ddb3ed43dc343e230f17c786e13046 183 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 118 128 - T 28-03-2018 IPR020549 Endoribonuclease YbeY, conserved site CU254_RS26445 31ddb3ed43dc343e230f17c786e13046 183 Pfam PF02130 Uncharacterized protein family UPF0054 15 147 3.4E-34 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CU254_RS26445 31ddb3ed43dc343e230f17c786e13046 183 SUPERFAMILY SSF55486 4 148 1.05E-36 T 28-03-2018 CU254_RS26445 31ddb3ed43dc343e230f17c786e13046 183 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 2 154 19.104 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CU254_RS26445 31ddb3ed43dc343e230f17c786e13046 183 Gene3D G3DSA:3.40.390.30 2 166 1.5E-41 T 28-03-2018 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 CU254_RS25005 ebb184557e18b2a233f578bf9313836e 410 SUPERFAMILY SSF55874 277 399 1.13E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS25005 ebb184557e18b2a233f578bf9313836e 410 Pfam PF07730 Histidine kinase 189 251 5.2E-13 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CU254_RS25005 ebb184557e18b2a233f578bf9313836e 410 Gene3D G3DSA:3.30.565.10 273 402 1.6E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS24840 485472d1f0e0abc4f8e1d259d1485104 191 SUPERFAMILY SSF46689 2 81 4.69E-20 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS24840 485472d1f0e0abc4f8e1d259d1485104 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 9.2E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS24840 485472d1f0e0abc4f8e1d259d1485104 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 9.2E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS24840 485472d1f0e0abc4f8e1d259d1485104 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 63 3.3E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS24840 485472d1f0e0abc4f8e1d259d1485104 191 Gene3D G3DSA:1.10.10.60 1 52 7.0E-22 T 28-03-2018 CU254_RS24840 485472d1f0e0abc4f8e1d259d1485104 191 Gene3D G3DSA:1.10.10.60 53 146 1.3E-10 T 28-03-2018 CU254_RS00210 6de60bfbc6d6037d42e8751fc26fc4b7 123 Pfam PF03795 YCII-related domain 1 115 5.4E-18 T 28-03-2018 IPR005545 YCII-related CU254_RS00210 6de60bfbc6d6037d42e8751fc26fc4b7 123 SUPERFAMILY SSF54909 1 116 1.07E-30 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS00210 6de60bfbc6d6037d42e8751fc26fc4b7 123 Gene3D G3DSA:3.30.70.1060 1 120 2.7E-38 T 28-03-2018 CU254_RS35995 6e4d38502962fc662a9a1ca183b49d4f 228 SUPERFAMILY SSF56784 3 214 5.26E-31 T 28-03-2018 IPR023214 HAD-like domain CU254_RS35995 6e4d38502962fc662a9a1ca183b49d4f 228 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 96 203 2.9E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CU254_RS35995 6e4d38502962fc662a9a1ca183b49d4f 228 Gene3D G3DSA:3.40.50.1000 1 214 3.4E-22 T 28-03-2018 IPR023214 HAD-like domain CU254_RS35995 6e4d38502962fc662a9a1ca183b49d4f 228 Pfam PF00702 haloacid dehalogenase-like hydrolase 3 193 1.1E-11 T 28-03-2018 CU254_RS35995 6e4d38502962fc662a9a1ca183b49d4f 228 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 154 194 3.2E-6 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CU254_RS02800 e3d352b24718280d096725c32ae5a3e8 257 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 169 180 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CU254_RS02800 e3d352b24718280d096725c32ae5a3e8 257 SUPERFAMILY SSF54292 20 127 2.54E-24 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CU254_RS02800 e3d352b24718280d096725c32ae5a3e8 257 SUPERFAMILY SSF46548 128 253 9.07E-33 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CU254_RS02800 e3d352b24718280d096725c32ae5a3e8 257 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 26 249 1.6E-74 T 28-03-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CU254_RS02800 e3d352b24718280d096725c32ae5a3e8 257 Gene3D G3DSA:3.10.20.30 11 127 6.7E-31 T 28-03-2018 IPR012675 Beta-grasp domain CU254_RS02800 e3d352b24718280d096725c32ae5a3e8 257 Gene3D G3DSA:1.10.1060.10 128 256 4.5E-27 T 28-03-2018 CU254_RS02800 e3d352b24718280d096725c32ae5a3e8 257 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 23 133 1.1E-32 T 28-03-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CU254_RS02800 e3d352b24718280d096725c32ae5a3e8 257 Pfam PF13183 4Fe-4S dicluster domain 167 239 4.7E-11 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CU254_RS22240 eb5a4adcba219ac994c9fb08c71b4a4d 1295 Gene3D G3DSA:2.160.10.10 708 823 2.0E-17 T 28-03-2018 CU254_RS22240 eb5a4adcba219ac994c9fb08c71b4a4d 1295 SUPERFAMILY SSF56801 25 531 6.67E-113 T 28-03-2018 CU254_RS22240 eb5a4adcba219ac994c9fb08c71b4a4d 1295 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 776 804 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CU254_RS22240 eb5a4adcba219ac994c9fb08c71b4a4d 1295 Gene3D G3DSA:2.160.10.10 924 1053 0.0026 T 28-03-2018 CU254_RS22240 eb5a4adcba219ac994c9fb08c71b4a4d 1295 Gene3D G3DSA:3.40.50.980 166 328 7.4E-40 T 28-03-2018 CU254_RS22240 eb5a4adcba219ac994c9fb08c71b4a4d 1295 Pfam PF00550 Phosphopantetheine attachment site 520 580 4.1E-9 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS22240 eb5a4adcba219ac994c9fb08c71b4a4d 1295 Gene3D G3DSA:3.30.300.30 407 525 1.0E-25 T 28-03-2018 CU254_RS22240 eb5a4adcba219ac994c9fb08c71b4a4d 1295 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 768 800 0.0014 T 28-03-2018 IPR001451 Hexapeptide repeat CU254_RS22240 eb5a4adcba219ac994c9fb08c71b4a4d 1295 SUPERFAMILY SSF51161 850 1055 4.12E-10 T 28-03-2018 IPR011004 Trimeric LpxA-like CU254_RS22240 eb5a4adcba219ac994c9fb08c71b4a4d 1295 ProSitePatterns PS00455 Putative AMP-binding domain signature. 164 175 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS22240 eb5a4adcba219ac994c9fb08c71b4a4d 1295 Gene3D G3DSA:2.30.38.10 329 402 3.3E-13 T 28-03-2018 CU254_RS22240 eb5a4adcba219ac994c9fb08c71b4a4d 1295 Gene3D G3DSA:1.10.1200.10 526 594 4.8E-15 T 28-03-2018 CU254_RS22240 eb5a4adcba219ac994c9fb08c71b4a4d 1295 Pfam PF13193 AMP-binding enzyme C-terminal domain 420 494 1.8E-5 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS22240 eb5a4adcba219ac994c9fb08c71b4a4d 1295 SUPERFAMILY SSF51161 1180 1294 3.05E-19 T 28-03-2018 IPR011004 Trimeric LpxA-like CU254_RS22240 eb5a4adcba219ac994c9fb08c71b4a4d 1295 TIGRFAM TIGR02353 NRPS_term_dom: non-ribosomal peptide synthetase terminal domain of unknown function 605 1290 1.1E-218 T 28-03-2018 IPR012728 Non-ribosomal peptide synthetase, C-terminal CU254_RS22240 eb5a4adcba219ac994c9fb08c71b4a4d 1295 Gene3D G3DSA:2.160.10.10 1140 1294 3.5E-16 T 28-03-2018 CU254_RS22240 eb5a4adcba219ac994c9fb08c71b4a4d 1295 SUPERFAMILY SSF47336 513 582 5.47E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS22240 eb5a4adcba219ac994c9fb08c71b4a4d 1295 Pfam PF00501 AMP-binding enzyme 43 411 1.2E-65 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS22240 eb5a4adcba219ac994c9fb08c71b4a4d 1295 Gene3D G3DSA:3.40.50.980 34 165 2.6E-27 T 28-03-2018 CU254_RS22240 eb5a4adcba219ac994c9fb08c71b4a4d 1295 SMART SM00823 Phosphopantetheine attachment site 518 586 9.8E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS22240 eb5a4adcba219ac994c9fb08c71b4a4d 1295 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 62 435 1.9E-98 T 28-03-2018 IPR010071 Amino acid adenylation domain CU254_RS22240 eb5a4adcba219ac994c9fb08c71b4a4d 1295 SUPERFAMILY SSF51161 717 817 2.08E-19 T 28-03-2018 IPR011004 Trimeric LpxA-like CU254_RS34305 6eda62910f390e50c954940b21020887 1024 SUPERFAMILY SSF52540 98 290 9.1E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS34305 6eda62910f390e50c954940b21020887 1024 SUPERFAMILY SSF52540 9 24 9.1E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS34305 6eda62910f390e50c954940b21020887 1024 SUPERFAMILY SSF52540 102 139 5.31E-6 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS34305 6eda62910f390e50c954940b21020887 1024 SUPERFAMILY SSF52540 511 578 5.31E-6 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS34305 6eda62910f390e50c954940b21020887 1024 Gene3D G3DSA:3.40.50.300 1 276 2.2E-23 T 28-03-2018 CU254_RS34305 6eda62910f390e50c954940b21020887 1024 Pfam PF04851 Type III restriction enzyme, res subunit 7 261 5.3E-17 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CU254_RS16720 15d67b283fdd08eca3e95cc07b07bb7e 1223 Pfam PF07705 CARDB 409 509 9.6E-23 T 28-03-2018 IPR011635 CARDB domain CU254_RS16720 15d67b283fdd08eca3e95cc07b07bb7e 1223 Pfam PF07705 CARDB 522 619 2.1E-14 T 28-03-2018 IPR011635 CARDB domain CU254_RS16720 15d67b283fdd08eca3e95cc07b07bb7e 1223 Gene3D G3DSA:2.60.120.260 629 794 1.0E-9 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS16720 15d67b283fdd08eca3e95cc07b07bb7e 1223 Gene3D G3DSA:2.60.120.260 22 168 4.5E-36 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS16720 15d67b283fdd08eca3e95cc07b07bb7e 1223 Gene3D G3DSA:2.60.120.260 254 404 1.3E-23 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS16720 15d67b283fdd08eca3e95cc07b07bb7e 1223 SUPERFAMILY SSF49785 267 404 6.17E-16 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS16720 15d67b283fdd08eca3e95cc07b07bb7e 1223 Gene3D G3DSA:2.60.40.10 169 253 1.1E-14 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS16720 15d67b283fdd08eca3e95cc07b07bb7e 1223 SUPERFAMILY SSF51126 784 1190 9.32E-37 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor CU254_RS16720 15d67b283fdd08eca3e95cc07b07bb7e 1223 Gene3D G3DSA:2.160.20.10 795 1202 8.0E-50 T 28-03-2018 IPR012334 Pectin lyase fold CU254_RS16720 15d67b283fdd08eca3e95cc07b07bb7e 1223 Pfam PF00754 F5/8 type C domain 276 399 2.7E-8 T 28-03-2018 IPR000421 Coagulation factor 5/8 C-terminal domain CU254_RS16720 15d67b283fdd08eca3e95cc07b07bb7e 1223 Pfam PF00754 F5/8 type C domain 49 166 1.2E-20 T 28-03-2018 IPR000421 Coagulation factor 5/8 C-terminal domain CU254_RS16720 15d67b283fdd08eca3e95cc07b07bb7e 1223 SUPERFAMILY SSF49785 45 172 8.51E-28 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS16720 15d67b283fdd08eca3e95cc07b07bb7e 1223 SUPERFAMILY SSF49265 178 246 2.92E-7 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CU254_RS16720 15d67b283fdd08eca3e95cc07b07bb7e 1223 Gene3D G3DSA:2.60.40.10 513 628 5.7E-13 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS16720 15d67b283fdd08eca3e95cc07b07bb7e 1223 Gene3D G3DSA:2.60.40.10 405 512 8.1E-19 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS16720 15d67b283fdd08eca3e95cc07b07bb7e 1223 SMART SM00710 1000 1022 2900.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CU254_RS16720 15d67b283fdd08eca3e95cc07b07bb7e 1223 SMART SM00710 976 998 830.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CU254_RS16720 15d67b283fdd08eca3e95cc07b07bb7e 1223 SMART SM00710 909 940 2600.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CU254_RS16720 15d67b283fdd08eca3e95cc07b07bb7e 1223 SMART SM00710 1152 1175 620.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CU254_RS16720 15d67b283fdd08eca3e95cc07b07bb7e 1223 SMART SM00710 1034 1057 110.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CU254_RS16720 15d67b283fdd08eca3e95cc07b07bb7e 1223 SMART SM00710 1089 1109 7000.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CU254_RS16720 15d67b283fdd08eca3e95cc07b07bb7e 1223 SMART SM00710 1125 1147 240.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CU254_RS16720 15d67b283fdd08eca3e95cc07b07bb7e 1223 SMART SM00710 1178 1199 4400.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CU254_RS16720 15d67b283fdd08eca3e95cc07b07bb7e 1223 SMART SM00710 943 964 270.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CU254_RS16720 15d67b283fdd08eca3e95cc07b07bb7e 1223 SMART SM00710 1058 1081 820.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CU254_RS16720 15d67b283fdd08eca3e95cc07b07bb7e 1223 Pfam PF12708 Pectate lyase superfamily protein 803 1023 1.1E-9 T 28-03-2018 IPR024535 Pectate lyase superfamily protein CU254_RS16720 15d67b283fdd08eca3e95cc07b07bb7e 1223 SMART SM00231 40 172 0.0015 T 28-03-2018 IPR000421 Coagulation factor 5/8 C-terminal domain CU254_RS03715 ae07c5a722865160a5403db26c6a6a60 151 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 5 141 1.5E-9 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase CU254_RS03715 ae07c5a722865160a5403db26c6a6a60 151 SUPERFAMILY SSF55961 5 144 4.48E-20 T 28-03-2018 CU254_RS03715 ae07c5a722865160a5403db26c6a6a60 151 Gene3D G3DSA:3.30.530.20 1 148 7.1E-19 T 28-03-2018 IPR023393 START-like domain CU254_RS11745 ae6e3c922392a2453a4c1fd44061b32e 745 Gene3D G3DSA:3.40.50.300 187 580 1.5E-31 T 28-03-2018 CU254_RS11745 ae6e3c922392a2453a4c1fd44061b32e 745 Gene3D G3DSA:3.40.50.300 595 744 4.7E-18 T 28-03-2018 CU254_RS11745 ae6e3c922392a2453a4c1fd44061b32e 745 Pfam PF13538 UvrD-like helicase C-terminal domain 685 732 3.9E-10 T 28-03-2018 IPR027785 UvrD-like helicase C-terminal domain CU254_RS11745 ae6e3c922392a2453a4c1fd44061b32e 745 Pfam PF13245 AAA domain 193 570 2.7E-10 T 28-03-2018 CU254_RS11745 ae6e3c922392a2453a4c1fd44061b32e 745 SUPERFAMILY SSF52540 182 260 6.61E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS11745 ae6e3c922392a2453a4c1fd44061b32e 745 SUPERFAMILY SSF52540 519 736 6.61E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS11745 ae6e3c922392a2453a4c1fd44061b32e 745 SUPERFAMILY SSF52540 344 352 6.61E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS15030 744d170cfce6932e77dc3750ae9bfa5e 207 PRINTS PR01703 Manganese superoxide dismutase signature 28 41 6.4E-19 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CU254_RS15030 744d170cfce6932e77dc3750ae9bfa5e 207 PRINTS PR01703 Manganese superoxide dismutase signature 7 18 6.4E-19 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CU254_RS15030 744d170cfce6932e77dc3750ae9bfa5e 207 PRINTS PR01703 Manganese superoxide dismutase signature 158 170 6.4E-19 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CU254_RS15030 744d170cfce6932e77dc3750ae9bfa5e 207 PRINTS PR01703 Manganese superoxide dismutase signature 120 128 6.4E-19 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CU254_RS15030 744d170cfce6932e77dc3750ae9bfa5e 207 PRINTS PR01703 Manganese superoxide dismutase signature 67 80 6.4E-19 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CU254_RS15030 744d170cfce6932e77dc3750ae9bfa5e 207 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 160 167 - T 28-03-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CU254_RS15030 744d170cfce6932e77dc3750ae9bfa5e 207 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 84 3.2E-29 T 28-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CU254_RS15030 744d170cfce6932e77dc3750ae9bfa5e 207 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 91 193 3.4E-33 T 28-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CU254_RS15030 744d170cfce6932e77dc3750ae9bfa5e 207 PIRSF PIRSF000349 1 202 5.2E-70 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CU254_RS15030 744d170cfce6932e77dc3750ae9bfa5e 207 Gene3D G3DSA:1.10.287.990 21 84 3.4E-17 T 28-03-2018 CU254_RS15030 744d170cfce6932e77dc3750ae9bfa5e 207 SUPERFAMILY SSF46609 3 88 6.81E-29 T 28-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CU254_RS15030 744d170cfce6932e77dc3750ae9bfa5e 207 SUPERFAMILY SSF54719 84 197 5.24E-41 T 28-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CU254_RS11705 056b791b5e142939ac605c6034231b57 219 Pfam PF00392 Bacterial regulatory proteins, gntR family 5 67 1.4E-18 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS11705 056b791b5e142939ac605c6034231b57 219 SMART SM00895 77 209 5.9E-13 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS11705 056b791b5e142939ac605c6034231b57 219 SUPERFAMILY SSF46785 5 71 1.45E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS11705 056b791b5e142939ac605c6034231b57 219 SMART SM00345 9 67 2.5E-12 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS11705 056b791b5e142939ac605c6034231b57 219 SUPERFAMILY SSF48008 75 215 3.14E-16 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS11705 056b791b5e142939ac605c6034231b57 219 Pfam PF07729 FCD domain 77 208 1.4E-20 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS11705 056b791b5e142939ac605c6034231b57 219 Gene3D G3DSA:1.10.10.10 1 62 5.8E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS11705 056b791b5e142939ac605c6034231b57 219 Gene3D G3DSA:1.20.120.530 63 218 7.8E-27 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS04680 c4f446c66a3536e75a7e1c17399dc853 275 SUPERFAMILY SSF51055 232 274 6.08E-14 T 28-03-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 CU254_RS04680 c4f446c66a3536e75a7e1c17399dc853 275 Gene3D G3DSA:2.10.10.20 231 274 3.4E-14 T 28-03-2018 CU254_RS04680 c4f446c66a3536e75a7e1c17399dc853 275 Pfam PF00775 Dioxygenase 62 207 6.5E-19 T 28-03-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 CU254_RS04680 c4f446c66a3536e75a7e1c17399dc853 275 SUPERFAMILY SSF49482 54 207 6.15E-45 T 28-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 CU254_RS04680 c4f446c66a3536e75a7e1c17399dc853 275 Gene3D G3DSA:2.60.130.10 42 217 1.1E-42 T 28-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 CU254_RS04680 c4f446c66a3536e75a7e1c17399dc853 275 SMART SM00495 229 275 4.1E-9 T 28-03-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 CU254_RS14140 54a99cbb9ef7b7a85cde87ec20f2b5f6 102 SUPERFAMILY SSF51182 22 96 2.1E-15 T 28-03-2018 IPR011051 RmlC-like cupin domain CU254_RS14140 54a99cbb9ef7b7a85cde87ec20f2b5f6 102 Pfam PF07883 Cupin domain 26 90 9.4E-13 T 28-03-2018 IPR013096 Cupin 2, conserved barrel CU254_RS14140 54a99cbb9ef7b7a85cde87ec20f2b5f6 102 Gene3D G3DSA:2.60.120.10 3 102 1.6E-15 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS21990 96885437d27380d3164c816c6ec56da1 324 Gene3D G3DSA:1.10.10.10 1 64 2.3E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS21990 96885437d27380d3164c816c6ec56da1 324 Pfam PF13280 WYL domain 141 316 2.3E-44 T 28-03-2018 IPR026881 WYL domain CU254_RS21990 96885437d27380d3164c816c6ec56da1 324 Gene3D G3DSA:1.10.10.10 175 323 0.45 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS21990 96885437d27380d3164c816c6ec56da1 324 PIRSF PIRSF016838 1 323 1.1E-22 T 28-03-2018 IPR028349 Protein PafC CU254_RS21990 96885437d27380d3164c816c6ec56da1 324 SUPERFAMILY SSF46785 3 59 7.13E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS21990 96885437d27380d3164c816c6ec56da1 324 Pfam PF08279 HTH domain 9 60 1.1E-16 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 CU254_RS08185 d5dea01455d1395571c6f11df4b3f62d 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 57 1.8E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS08185 d5dea01455d1395571c6f11df4b3f62d 200 SUPERFAMILY SSF48498 79 186 1.42E-16 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS08185 d5dea01455d1395571c6f11df4b3f62d 200 Gene3D G3DSA:1.10.357.10 59 187 1.2E-19 T 28-03-2018 CU254_RS08185 d5dea01455d1395571c6f11df4b3f62d 200 Gene3D G3DSA:1.10.10.60 2 58 2.1E-12 T 28-03-2018 CU254_RS08185 d5dea01455d1395571c6f11df4b3f62d 200 SUPERFAMILY SSF46689 4 77 2.72E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS37340 eb3bedb5d0332caeb3ed9d85426d16e6 508 PIRSF PIRSF006060 7 485 3.8E-49 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CU254_RS37340 eb3bedb5d0332caeb3ed9d85426d16e6 508 Pfam PF13520 Amino acid permease 21 463 8.2E-36 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CU254_RS38375 69915bdaa9967ce34b5d853db561d465 1331 Pfam PF01345 Domain of unknown function DUF11 842 881 1.9E-8 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CU254_RS38375 69915bdaa9967ce34b5d853db561d465 1331 Pfam PF01345 Domain of unknown function DUF11 238 330 5.7E-7 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CU254_RS38375 69915bdaa9967ce34b5d853db561d465 1331 Pfam PF01345 Domain of unknown function DUF11 1238 1315 5.0E-6 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CU254_RS38375 69915bdaa9967ce34b5d853db561d465 1331 Gene3D G3DSA:2.60.40.10 838 929 2.2E-12 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS38375 69915bdaa9967ce34b5d853db561d465 1331 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1047 1075 6.7E-4 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CU254_RS38375 69915bdaa9967ce34b5d853db561d465 1331 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 444 474 3.7E-5 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CU254_RS38375 69915bdaa9967ce34b5d853db561d465 1331 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 244 273 5.6E-4 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CU254_RS38375 69915bdaa9967ce34b5d853db561d465 1331 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1246 1274 1.4E-4 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CU254_RS38375 69915bdaa9967ce34b5d853db561d465 1331 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 345 373 2.3E-5 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CU254_RS38375 69915bdaa9967ce34b5d853db561d465 1331 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 644 677 6.4E-5 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CU254_RS38375 69915bdaa9967ce34b5d853db561d465 1331 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 945 977 6.0E-6 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CU254_RS38375 69915bdaa9967ce34b5d853db561d465 1331 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 45 72 2.5E-4 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CU254_RS38375 69915bdaa9967ce34b5d853db561d465 1331 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 851 879 6.0E-8 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CU254_RS38375 69915bdaa9967ce34b5d853db561d465 1331 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 140 173 6.8E-5 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CU254_RS38375 69915bdaa9967ce34b5d853db561d465 1331 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 744 777 1.7E-5 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CU254_RS38375 69915bdaa9967ce34b5d853db561d465 1331 Gene3D G3DSA:2.60.40.10 533 626 2.7E-8 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS38375 69915bdaa9967ce34b5d853db561d465 1331 Gene3D G3DSA:2.60.40.10 1230 1328 7.6E-13 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS38375 69915bdaa9967ce34b5d853db561d465 1331 Gene3D G3DSA:2.60.40.10 1029 1127 1.2E-14 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS38375 69915bdaa9967ce34b5d853db561d465 1331 Gene3D G3DSA:2.60.40.10 1128 1229 4.3E-8 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS38375 69915bdaa9967ce34b5d853db561d465 1331 Gene3D G3DSA:2.60.40.10 219 325 8.6E-15 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS38375 69915bdaa9967ce34b5d853db561d465 1331 Gene3D G3DSA:2.60.40.10 930 1028 1.9E-11 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS38375 69915bdaa9967ce34b5d853db561d465 1331 Gene3D G3DSA:2.60.40.10 121 213 4.0E-12 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS38375 69915bdaa9967ce34b5d853db561d465 1331 Gene3D G3DSA:2.60.40.10 20 120 5.1E-11 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS38375 69915bdaa9967ce34b5d853db561d465 1331 Gene3D G3DSA:2.60.40.10 326 424 2.4E-14 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS38375 69915bdaa9967ce34b5d853db561d465 1331 Gene3D G3DSA:2.60.40.10 627 731 1.0E-10 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS38375 69915bdaa9967ce34b5d853db561d465 1331 Gene3D G3DSA:2.60.40.10 732 837 6.6E-13 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS38375 69915bdaa9967ce34b5d853db561d465 1331 Gene3D G3DSA:2.60.40.10 425 532 2.9E-11 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS07365 38bce61e9b2e16987ed0824981463bd9 448 Pfam PF00120 Glutamine synthetase, catalytic domain 115 441 1.3E-100 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CU254_RS07365 38bce61e9b2e16987ed0824981463bd9 448 SMART SM01230 114 366 2.2E-98 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CU254_RS07365 38bce61e9b2e16987ed0824981463bd9 448 Gene3D G3DSA:3.10.20.70 1 113 3.0E-22 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CU254_RS07365 38bce61e9b2e16987ed0824981463bd9 448 SUPERFAMILY SSF54368 3 113 1.31E-16 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CU254_RS07365 38bce61e9b2e16987ed0824981463bd9 448 Gene3D G3DSA:3.30.590.10 114 448 9.2E-99 T 28-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CU254_RS07365 38bce61e9b2e16987ed0824981463bd9 448 SUPERFAMILY SSF55931 115 446 1.18E-101 T 28-03-2018 CU254_RS13885 5e86f1bfb3d89bae13430501531f2cd4 316 Gene3D G3DSA:3.40.190.10 95 171 1.9E-10 T 28-03-2018 CU254_RS13885 5e86f1bfb3d89bae13430501531f2cd4 316 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 66 4.2E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS13885 5e86f1bfb3d89bae13430501531f2cd4 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 1.1E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS13885 5e86f1bfb3d89bae13430501531f2cd4 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 1.1E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS13885 5e86f1bfb3d89bae13430501531f2cd4 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 1.1E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS13885 5e86f1bfb3d89bae13430501531f2cd4 316 Gene3D G3DSA:1.10.10.10 1 88 5.5E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS13885 5e86f1bfb3d89bae13430501531f2cd4 316 SUPERFAMILY SSF46785 4 115 1.42E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS13885 5e86f1bfb3d89bae13430501531f2cd4 316 Pfam PF03466 LysR substrate binding domain 94 297 7.4E-27 T 28-03-2018 IPR005119 LysR, substrate-binding CU254_RS13885 5e86f1bfb3d89bae13430501531f2cd4 316 SUPERFAMILY SSF53850 94 301 1.57E-26 T 28-03-2018 CU254_RS13885 5e86f1bfb3d89bae13430501531f2cd4 316 Gene3D G3DSA:3.40.190.10 172 272 7.4E-15 T 28-03-2018 CU254_RS17830 dbde3003a5c184314d8e7fe26be3ce47 212 SMART SM00345 12 70 9.1E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS17830 dbde3003a5c184314d8e7fe26be3ce47 212 SMART SM00895 80 203 3.4E-21 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS17830 dbde3003a5c184314d8e7fe26be3ce47 212 SUPERFAMILY SSF46785 6 74 7.89E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS17830 dbde3003a5c184314d8e7fe26be3ce47 212 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 69 1.7E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS17830 dbde3003a5c184314d8e7fe26be3ce47 212 SUPERFAMILY SSF48008 76 210 5.49E-24 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS17830 dbde3003a5c184314d8e7fe26be3ce47 212 Gene3D G3DSA:1.20.120.530 66 212 2.1E-29 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS17830 dbde3003a5c184314d8e7fe26be3ce47 212 Gene3D G3DSA:1.10.10.10 2 65 4.5E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS17830 dbde3003a5c184314d8e7fe26be3ce47 212 Pfam PF07729 FCD domain 81 201 2.1E-23 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS36280 760a5d9fae9d87465a3714b046daa37a 302 Gene3D G3DSA:3.40.50.620 1 185 1.6E-70 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS36280 760a5d9fae9d87465a3714b046daa37a 302 SUPERFAMILY SSF52374 9 287 2.5E-100 T 28-03-2018 CU254_RS36280 760a5d9fae9d87465a3714b046daa37a 302 Pfam PF02569 Pantoate-beta-alanine ligase 17 283 1.1E-92 T 28-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 CU254_RS36280 760a5d9fae9d87465a3714b046daa37a 302 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 20 283 1.2E-84 T 28-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 CU254_RS36280 760a5d9fae9d87465a3714b046daa37a 302 Gene3D G3DSA:3.30.1300.10 186 299 4.8E-34 T 28-03-2018 CU254_RS36280 760a5d9fae9d87465a3714b046daa37a 302 Hamap MF_00158 Pantothenate synthetase [panC]. 12 285 37.989 T 28-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 CU254_RS37025 2335793f4ed71756d5cea6aa19b6e9a2 311 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 124 310 7.3E-30 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS37025 2335793f4ed71756d5cea6aa19b6e9a2 311 Gene3D G3DSA:1.10.3720.10 22 299 1.8E-44 T 28-03-2018 CU254_RS37025 2335793f4ed71756d5cea6aa19b6e9a2 311 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 24 67 5.6E-11 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CU254_RS37025 2335793f4ed71756d5cea6aa19b6e9a2 311 SUPERFAMILY SSF161098 101 291 4.84E-29 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS38310 321cfbf12be5bc16fd94688e9c67f1c8 235 Hamap MF_01151 Protein GrpE [grpE]. 6 203 16.951 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CU254_RS38310 321cfbf12be5bc16fd94688e9c67f1c8 235 SUPERFAMILY SSF51064 148 204 9.55E-16 T 28-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 CU254_RS38310 321cfbf12be5bc16fd94688e9c67f1c8 235 Pfam PF01025 GrpE 65 202 6.3E-33 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CU254_RS38310 321cfbf12be5bc16fd94688e9c67f1c8 235 Gene3D G3DSA:3.90.20.20 54 146 1.6E-15 T 28-03-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 CU254_RS38310 321cfbf12be5bc16fd94688e9c67f1c8 235 PRINTS PR00773 GrpE protein signature 182 201 1.7E-23 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CU254_RS38310 321cfbf12be5bc16fd94688e9c67f1c8 235 PRINTS PR00773 GrpE protein signature 155 170 1.7E-23 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CU254_RS38310 321cfbf12be5bc16fd94688e9c67f1c8 235 PRINTS PR00773 GrpE protein signature 108 123 1.7E-23 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CU254_RS38310 321cfbf12be5bc16fd94688e9c67f1c8 235 PRINTS PR00773 GrpE protein signature 80 96 1.7E-23 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CU254_RS38310 321cfbf12be5bc16fd94688e9c67f1c8 235 SUPERFAMILY SSF58014 60 147 3.66E-17 T 28-03-2018 CU254_RS38310 321cfbf12be5bc16fd94688e9c67f1c8 235 Gene3D G3DSA:2.30.22.10 147 209 2.4E-20 T 28-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 CU254_RS38310 321cfbf12be5bc16fd94688e9c67f1c8 235 ProSitePatterns PS01071 grpE protein signature. 158 201 - T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CU254_RS31330 93ab7cd27b6086ce258606ff7a6ece60 114 SUPERFAMILY SSF46955 1 111 8.79E-25 T 28-03-2018 IPR009061 Putative DNA-binding domain CU254_RS31330 93ab7cd27b6086ce258606ff7a6ece60 114 SMART SM00422 1 69 3.9E-20 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS31330 93ab7cd27b6086ce258606ff7a6ece60 114 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 3.2E-7 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS31330 93ab7cd27b6086ce258606ff7a6ece60 114 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 3.2E-7 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS31330 93ab7cd27b6086ce258606ff7a6ece60 114 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 3.2E-7 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS31330 93ab7cd27b6086ce258606ff7a6ece60 114 Gene3D G3DSA:1.10.1660.10 1 55 2.3E-20 T 28-03-2018 CU254_RS31330 93ab7cd27b6086ce258606ff7a6ece60 114 Gene3D G3DSA:1.10.1660.10 56 114 2.4E-10 T 28-03-2018 CU254_RS31330 93ab7cd27b6086ce258606ff7a6ece60 114 Pfam PF13411 MerR HTH family regulatory protein 2 67 2.8E-18 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS08340 4847e1fc9b870fd0e8308291934471d6 274 SUPERFAMILY SSF46689 207 255 8.06E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS08340 4847e1fc9b870fd0e8308291934471d6 274 Gene3D G3DSA:1.10.10.60 145 208 4.6E-10 T 28-03-2018 CU254_RS08340 4847e1fc9b870fd0e8308291934471d6 274 Gene3D G3DSA:1.10.10.60 209 258 5.2E-10 T 28-03-2018 CU254_RS08340 4847e1fc9b870fd0e8308291934471d6 274 Pfam PF12833 Helix-turn-helix domain 177 254 2.4E-19 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS08340 4847e1fc9b870fd0e8308291934471d6 274 SMART SM00342 171 254 3.0E-16 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS19900 6a350712f06a97f156df47a276221334 447 Gene3D G3DSA:1.10.285.10 7 62 1.6E-4 T 28-03-2018 CU254_RS19900 6a350712f06a97f156df47a276221334 447 SUPERFAMILY SSF53223 9 197 8.64E-68 T 28-03-2018 CU254_RS19900 6a350712f06a97f156df47a276221334 447 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 203 443 4.6E-81 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CU254_RS19900 6a350712f06a97f156df47a276221334 447 SMART SM00839 204 445 3.5E-88 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CU254_RS19900 6a350712f06a97f156df47a276221334 447 SUPERFAMILY SSF51735 203 446 2.03E-71 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS19900 6a350712f06a97f156df47a276221334 447 Gene3D G3DSA:3.40.50.10860 63 190 1.7E-49 T 28-03-2018 CU254_RS19900 6a350712f06a97f156df47a276221334 447 Gene3D G3DSA:3.40.50.720 203 447 4.7E-68 T 28-03-2018 CU254_RS19900 6a350712f06a97f156df47a276221334 447 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 194 216 2.7E-25 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CU254_RS19900 6a350712f06a97f156df47a276221334 447 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 114 128 2.7E-25 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CU254_RS19900 6a350712f06a97f156df47a276221334 447 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 236 256 2.7E-25 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CU254_RS19900 6a350712f06a97f156df47a276221334 447 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 371 382 2.7E-25 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CU254_RS19900 6a350712f06a97f156df47a276221334 447 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 57 185 8.6E-46 T 28-03-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CU254_RS19900 6a350712f06a97f156df47a276221334 447 PIRSF PIRSF000185 22 447 4.4E-109 T 28-03-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 CU254_RS26820 53808bd5ff3c5166547a1ba01c885040 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 72 2.5E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS26820 53808bd5ff3c5166547a1ba01c885040 207 Gene3D G3DSA:1.10.357.10 62 205 1.1E-13 T 28-03-2018 CU254_RS26820 53808bd5ff3c5166547a1ba01c885040 207 SUPERFAMILY SSF46689 13 81 1.54E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS26820 53808bd5ff3c5166547a1ba01c885040 207 SUPERFAMILY SSF48498 102 197 1.51E-9 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS26820 53808bd5ff3c5166547a1ba01c885040 207 Gene3D G3DSA:1.10.10.60 3 61 1.2E-20 T 28-03-2018 CU254_RS26820 53808bd5ff3c5166547a1ba01c885040 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 1.7E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS26820 53808bd5ff3c5166547a1ba01c885040 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 1.7E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS40505 14ead4c70685e6ab8b79fb6dd08e74b9 278 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 193 2.0E-5 T 28-03-2018 CU254_RS40505 14ead4c70685e6ab8b79fb6dd08e74b9 278 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 1.1E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS40505 14ead4c70685e6ab8b79fb6dd08e74b9 278 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.1E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS40505 14ead4c70685e6ab8b79fb6dd08e74b9 278 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.1E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS40505 14ead4c70685e6ab8b79fb6dd08e74b9 278 Gene3D G3DSA:3.40.50.720 1 187 3.7E-58 T 28-03-2018 CU254_RS40505 14ead4c70685e6ab8b79fb6dd08e74b9 278 Pfam PF00106 short chain dehydrogenase 7 199 3.1E-50 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS40505 14ead4c70685e6ab8b79fb6dd08e74b9 278 Gene3D G3DSA:3.40.50.720 188 242 0.17 T 28-03-2018 CU254_RS40505 14ead4c70685e6ab8b79fb6dd08e74b9 278 SUPERFAMILY SSF51735 1 263 1.12E-67 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS40505 14ead4c70685e6ab8b79fb6dd08e74b9 278 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS40505 14ead4c70685e6ab8b79fb6dd08e74b9 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 6.7E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS40505 14ead4c70685e6ab8b79fb6dd08e74b9 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 6.7E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS40505 14ead4c70685e6ab8b79fb6dd08e74b9 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 6.7E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS40505 14ead4c70685e6ab8b79fb6dd08e74b9 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 6.7E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS40505 14ead4c70685e6ab8b79fb6dd08e74b9 278 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 6.7E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS07385 21b962f068f2c0d00b211444e647be82 943 SUPERFAMILY SSF53383 9 431 1.64E-95 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS07385 21b962f068f2c0d00b211444e647be82 943 Gene3D G3DSA:3.90.1150.10 336 436 1.7E-25 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS07385 21b962f068f2c0d00b211444e647be82 943 Gene3D G3DSA:3.40.640.10 87 335 8.4E-33 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS07385 21b962f068f2c0d00b211444e647be82 943 Pfam PF02347 Glycine cleavage system P-protein 9 434 1.7E-172 T 28-03-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 CU254_RS07385 21b962f068f2c0d00b211444e647be82 943 Gene3D G3DSA:3.40.640.10 512 757 2.0E-38 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS07385 21b962f068f2c0d00b211444e647be82 943 Pfam PF00266 Aminotransferase class-V 565 698 6.9E-5 T 28-03-2018 IPR000192 Aminotransferase class V domain CU254_RS07385 21b962f068f2c0d00b211444e647be82 943 SUPERFAMILY SSF53383 426 872 2.16E-97 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS07385 21b962f068f2c0d00b211444e647be82 943 SUPERFAMILY SSF53383 914 937 2.16E-97 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS07385 21b962f068f2c0d00b211444e647be82 943 Gene3D G3DSA:3.90.1150.10 758 890 4.3E-42 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS07385 21b962f068f2c0d00b211444e647be82 943 TIGRFAM TIGR00461 gcvP: glycine dehydrogenase 9 935 0.0 T 28-03-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 CU254_RS07385 21b962f068f2c0d00b211444e647be82 943 Hamap MF_00711 Glycine dehydrogenase (decarboxylating) [gcvP]. 1 941 24.435 T 28-03-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 CU254_RS32585 3d867e6e1fd369707f7cbdb811792349 154 Pfam PF06262 Zincin-like metallopeptidase 62 151 2.1E-10 T 28-03-2018 IPR010428 Zincin-like metallopeptidase CU254_RS32585 3d867e6e1fd369707f7cbdb811792349 154 SUPERFAMILY SSF55486 35 152 1.28E-25 T 28-03-2018 CU254_RS20320 5d7cacb4c65eb6f76dfb46d497e80c8a 87 Hamap MF_00502 50S ribosomal protein L31 type B [rpmE2]. 1 81 25.412 T 28-03-2018 IPR027493 Ribosomal protein L31 type B GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS20320 5d7cacb4c65eb6f76dfb46d497e80c8a 87 SUPERFAMILY SSF143800 2 80 1.49E-20 T 28-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS20320 5d7cacb4c65eb6f76dfb46d497e80c8a 87 PRINTS PR01249 Ribosomal protein L31 signature 45 60 1.0E-16 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS20320 5d7cacb4c65eb6f76dfb46d497e80c8a 87 PRINTS PR01249 Ribosomal protein L31 signature 60 78 1.0E-16 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS20320 5d7cacb4c65eb6f76dfb46d497e80c8a 87 PRINTS PR01249 Ribosomal protein L31 signature 2 19 1.0E-16 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS20320 5d7cacb4c65eb6f76dfb46d497e80c8a 87 TIGRFAM TIGR00105 L31: ribosomal protein bL31 2 80 9.3E-20 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS20320 5d7cacb4c65eb6f76dfb46d497e80c8a 87 ProSitePatterns PS01143 Ribosomal protein L31 signature. 49 70 - T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS20320 5d7cacb4c65eb6f76dfb46d497e80c8a 87 Pfam PF01197 Ribosomal protein L31 2 79 2.9E-28 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS17140 e46b88a89d0a1b980d2f9b73480095bd 269 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 83 260 1.6E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS17140 e46b88a89d0a1b980d2f9b73480095bd 269 SUPERFAMILY SSF161098 6 268 1.12E-67 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS17140 e46b88a89d0a1b980d2f9b73480095bd 269 Gene3D G3DSA:1.10.3720.10 2 256 4.7E-43 T 28-03-2018 CU254_RS12800 22484731d75bbb76e4e99d5ee3f9c95d 316 Gene3D G3DSA:3.50.30.50 54 316 6.2E-39 T 28-03-2018 CU254_RS12800 22484731d75bbb76e4e99d5ee3f9c95d 316 Pfam PF04199 Putative cyclase 95 245 2.2E-20 T 28-03-2018 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 CU254_RS12800 22484731d75bbb76e4e99d5ee3f9c95d 316 SUPERFAMILY SSF102198 89 315 2.49E-23 T 28-03-2018 CU254_RS07660 c7009590a13508bfdd99f5309275d22c 333 Gene3D G3DSA:3.40.50.2300 41 167 1.0E-21 T 28-03-2018 CU254_RS07660 c7009590a13508bfdd99f5309275d22c 333 Pfam PF13407 Periplasmic binding protein domain 54 296 9.6E-40 T 28-03-2018 IPR025997 Periplasmic binding protein CU254_RS07660 c7009590a13508bfdd99f5309275d22c 333 SUPERFAMILY SSF53822 51 324 3.3E-50 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CU254_RS07660 c7009590a13508bfdd99f5309275d22c 333 Gene3D G3DSA:3.40.50.2300 168 294 1.2E-15 T 28-03-2018 CU254_RS35820 96c949bbdc7aa72321148bac40365a8f 181 Gene3D G3DSA:1.10.10.60 1 41 1.9E-13 T 28-03-2018 CU254_RS35820 96c949bbdc7aa72321148bac40365a8f 181 Gene3D G3DSA:1.10.357.10 66 181 1.0E-9 T 28-03-2018 CU254_RS35820 96c949bbdc7aa72321148bac40365a8f 181 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 60 1.1E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS35820 96c949bbdc7aa72321148bac40365a8f 181 SUPERFAMILY SSF48498 80 178 6.04E-9 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS35820 96c949bbdc7aa72321148bac40365a8f 181 SUPERFAMILY SSF46689 6 76 7.98E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS35820 96c949bbdc7aa72321148bac40365a8f 181 Gene3D G3DSA:1.10.260.40 42 65 3.5E-10 T 28-03-2018 CU254_RS41870 e4d2fed0c29537619bfbf6e5069ea1df 383 Gene3D G3DSA:1.10.287.110 303 381 7.8E-13 T 28-03-2018 IPR001623 DnaJ domain CU254_RS41870 e4d2fed0c29537619bfbf6e5069ea1df 383 SUPERFAMILY SSF46565 308 378 5.89E-13 T 28-03-2018 IPR001623 DnaJ domain CU254_RS41870 e4d2fed0c29537619bfbf6e5069ea1df 383 SMART SM00271 307 372 2.6E-6 T 28-03-2018 IPR001623 DnaJ domain CU254_RS41870 e4d2fed0c29537619bfbf6e5069ea1df 383 Pfam PF00226 DnaJ domain 308 377 8.6E-10 T 28-03-2018 IPR001623 DnaJ domain CU254_RS09645 77ff644b8e83175cb5a44fce4eb7106f 638 Pfam PF02910 Fumarate reductase flavoprotein C-term 487 594 8.0E-24 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CU254_RS09645 77ff644b8e83175cb5a44fce4eb7106f 638 SUPERFAMILY SSF46977 480 634 5.23E-42 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CU254_RS09645 77ff644b8e83175cb5a44fce4eb7106f 638 Gene3D G3DSA:1.20.58.100 466 573 5.7E-29 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CU254_RS09645 77ff644b8e83175cb5a44fce4eb7106f 638 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 8.9E-6 T 28-03-2018 CU254_RS09645 77ff644b8e83175cb5a44fce4eb7106f 638 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 393 415 8.9E-6 T 28-03-2018 CU254_RS09645 77ff644b8e83175cb5a44fce4eb7106f 638 Pfam PF00890 FAD binding domain 10 429 6.5E-90 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CU254_RS09645 77ff644b8e83175cb5a44fce4eb7106f 638 SUPERFAMILY SSF56425 243 389 1.05E-32 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CU254_RS09645 77ff644b8e83175cb5a44fce4eb7106f 638 Gene3D G3DSA:3.50.50.60 1 465 1.4E-67 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS09645 77ff644b8e83175cb5a44fce4eb7106f 638 PIRSF PIRSF000171 1 603 3.5E-38 T 28-03-2018 CU254_RS09645 77ff644b8e83175cb5a44fce4eb7106f 638 SUPERFAMILY SSF51905 3 270 1.2E-74 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS09645 77ff644b8e83175cb5a44fce4eb7106f 638 SUPERFAMILY SSF51905 393 469 1.2E-74 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS13685 6781083d2d2400cd984066ed13fabcde 212 SMART SM00345 11 69 4.0E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS13685 6781083d2d2400cd984066ed13fabcde 212 Gene3D G3DSA:1.10.10.10 2 71 4.0E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS13685 6781083d2d2400cd984066ed13fabcde 212 SMART SM00895 79 208 6.5E-13 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS13685 6781083d2d2400cd984066ed13fabcde 212 SUPERFAMILY SSF46785 6 73 1.05E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS13685 6781083d2d2400cd984066ed13fabcde 212 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 29 43 1.3E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS13685 6781083d2d2400cd984066ed13fabcde 212 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 59 1.3E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS13685 6781083d2d2400cd984066ed13fabcde 212 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 69 4.3E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS13685 6781083d2d2400cd984066ed13fabcde 212 Pfam PF07729 FCD domain 79 206 1.7E-19 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS13685 6781083d2d2400cd984066ed13fabcde 212 SUPERFAMILY SSF48008 75 211 1.54E-21 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS13685 6781083d2d2400cd984066ed13fabcde 212 Gene3D G3DSA:1.20.120.530 72 212 9.5E-28 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS34215 eea74fc1bce7afcb4f704d3cc81fa1f5 382 Gene3D G3DSA:3.90.420.10 229 382 1.9E-31 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CU254_RS34215 eea74fc1bce7afcb4f704d3cc81fa1f5 382 Pfam PF00174 Oxidoreductase molybdopterin binding domain 251 380 3.6E-20 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CU254_RS34215 eea74fc1bce7afcb4f704d3cc81fa1f5 382 SUPERFAMILY SSF56524 251 380 6.41E-29 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CU254_RS34215 eea74fc1bce7afcb4f704d3cc81fa1f5 382 Gene3D G3DSA:1.20.950.20 12 176 4.5E-6 T 28-03-2018 CU254_RS22845 e7687bbb2704ae8854414a6b6631cf4d 497 SUPERFAMILY SSF50249 214 298 2.33E-27 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CU254_RS22845 e7687bbb2704ae8854414a6b6631cf4d 497 Gene3D G3DSA:2.40.50.140 209 290 1.5E-26 T 28-03-2018 CU254_RS22845 e7687bbb2704ae8854414a6b6631cf4d 497 SMART SM00316 41 112 4.0E-17 T 28-03-2018 IPR022967 RNA-binding domain, S1 CU254_RS22845 e7687bbb2704ae8854414a6b6631cf4d 497 SMART SM00316 128 195 1.6E-9 T 28-03-2018 IPR022967 RNA-binding domain, S1 CU254_RS22845 e7687bbb2704ae8854414a6b6631cf4d 497 SMART SM00316 214 284 8.9E-28 T 28-03-2018 IPR022967 RNA-binding domain, S1 CU254_RS22845 e7687bbb2704ae8854414a6b6631cf4d 497 SMART SM00316 299 370 1.0E-22 T 28-03-2018 IPR022967 RNA-binding domain, S1 CU254_RS22845 e7687bbb2704ae8854414a6b6631cf4d 497 SUPERFAMILY SSF50249 114 198 3.36E-14 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CU254_RS22845 e7687bbb2704ae8854414a6b6631cf4d 497 Gene3D G3DSA:2.40.50.140 301 447 5.3E-24 T 28-03-2018 CU254_RS22845 e7687bbb2704ae8854414a6b6631cf4d 497 SUPERFAMILY SSF50249 284 372 3.43E-24 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CU254_RS22845 e7687bbb2704ae8854414a6b6631cf4d 497 Gene3D G3DSA:2.40.50.140 127 204 1.6E-11 T 28-03-2018 CU254_RS22845 e7687bbb2704ae8854414a6b6631cf4d 497 Gene3D G3DSA:2.40.50.140 20 117 1.4E-18 T 28-03-2018 CU254_RS22845 e7687bbb2704ae8854414a6b6631cf4d 497 PRINTS PR00681 Ribosomal protein S1 signature 61 75 1.6E-87 T 28-03-2018 CU254_RS22845 e7687bbb2704ae8854414a6b6631cf4d 497 PRINTS PR00681 Ribosomal protein S1 signature 314 333 1.6E-87 T 28-03-2018 CU254_RS22845 e7687bbb2704ae8854414a6b6631cf4d 497 PRINTS PR00681 Ribosomal protein S1 signature 150 167 1.6E-87 T 28-03-2018 CU254_RS22845 e7687bbb2704ae8854414a6b6631cf4d 497 PRINTS PR00681 Ribosomal protein S1 signature 179 199 1.6E-87 T 28-03-2018 CU254_RS22845 e7687bbb2704ae8854414a6b6631cf4d 497 PRINTS PR00681 Ribosomal protein S1 signature 109 128 1.6E-87 T 28-03-2018 CU254_RS22845 e7687bbb2704ae8854414a6b6631cf4d 497 PRINTS PR00681 Ribosomal protein S1 signature 353 371 1.6E-87 T 28-03-2018 CU254_RS22845 e7687bbb2704ae8854414a6b6631cf4d 497 PRINTS PR00681 Ribosomal protein S1 signature 236 257 1.6E-87 T 28-03-2018 CU254_RS22845 e7687bbb2704ae8854414a6b6631cf4d 497 PRINTS PR00681 Ribosomal protein S1 signature 133 149 1.6E-87 T 28-03-2018 CU254_RS22845 e7687bbb2704ae8854414a6b6631cf4d 497 PRINTS PR00681 Ribosomal protein S1 signature 43 61 1.6E-87 T 28-03-2018 CU254_RS22845 e7687bbb2704ae8854414a6b6631cf4d 497 Pfam PF00575 S1 RNA binding domain 214 284 5.5E-26 T 28-03-2018 IPR003029 S1 domain GO:0003676 CU254_RS22845 e7687bbb2704ae8854414a6b6631cf4d 497 Pfam PF00575 S1 RNA binding domain 128 195 1.3E-13 T 28-03-2018 IPR003029 S1 domain GO:0003676 CU254_RS22845 e7687bbb2704ae8854414a6b6631cf4d 497 Pfam PF00575 S1 RNA binding domain 298 370 2.2E-21 T 28-03-2018 IPR003029 S1 domain GO:0003676 CU254_RS22845 e7687bbb2704ae8854414a6b6631cf4d 497 Pfam PF00575 S1 RNA binding domain 40 112 2.3E-15 T 28-03-2018 IPR003029 S1 domain GO:0003676 CU254_RS22845 e7687bbb2704ae8854414a6b6631cf4d 497 SUPERFAMILY SSF50249 35 137 1.12E-22 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CU254_RS05000 39d424aad30595e833b9d5ccf59e9cf1 800 Gene3D G3DSA:3.40.50.300 177 339 1.2E-37 T 28-03-2018 CU254_RS05000 39d424aad30595e833b9d5ccf59e9cf1 800 SMART SM00847 380 474 9.3E-9 T 28-03-2018 IPR007502 Helicase-associated domain GO:0004386 CU254_RS05000 39d424aad30595e833b9d5ccf59e9cf1 800 TIGRFAM TIGR01970 DEAH_box_HrpB: ATP-dependent helicase HrpB 4 798 1.7E-242 T 28-03-2018 IPR010225 ATP-dependent helicase HrpB GO:0008026 CU254_RS05000 39d424aad30595e833b9d5ccf59e9cf1 800 SUPERFAMILY SSF52540 16 330 1.76E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS05000 39d424aad30595e833b9d5ccf59e9cf1 800 PIRSF PIRSF005496 1 800 4.0E-274 T 28-03-2018 CU254_RS05000 39d424aad30595e833b9d5ccf59e9cf1 800 Gene3D G3DSA:3.40.50.300 3 159 7.5E-22 T 28-03-2018 CU254_RS05000 39d424aad30595e833b9d5ccf59e9cf1 800 Pfam PF08482 ATP-dependent helicase C-terminal 660 786 1.2E-50 T 28-03-2018 IPR013689 ATP-dependent RNA helicase HrpB, C-terminal CU254_RS05000 39d424aad30595e833b9d5ccf59e9cf1 800 SMART SM00490 223 320 8.0E-13 T 28-03-2018 IPR001650 Helicase, C-terminal CU254_RS05000 39d424aad30595e833b9d5ccf59e9cf1 800 SMART SM00487 2 183 8.6E-15 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CU254_RS05000 39d424aad30595e833b9d5ccf59e9cf1 800 Pfam PF04408 Helicase associated domain (HA2) 381 465 3.3E-11 T 28-03-2018 IPR007502 Helicase-associated domain GO:0004386 CU254_RS05000 39d424aad30595e833b9d5ccf59e9cf1 800 Pfam PF00271 Helicase conserved C-terminal domain 205 318 5.4E-10 T 28-03-2018 IPR001650 Helicase, C-terminal CU254_RS03375 521ae48b4f40e182e52aa9ffefd1d2ca 427 SUPERFAMILY SSF55874 266 400 6.02E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS03375 521ae48b4f40e182e52aa9ffefd1d2ca 427 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 311 405 1.3E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS03375 521ae48b4f40e182e52aa9ffefd1d2ca 427 Pfam PF00672 HAMP domain 149 191 5.6E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS03375 521ae48b4f40e182e52aa9ffefd1d2ca 427 SUPERFAMILY SSF47384 187 263 7.46E-8 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS03375 521ae48b4f40e182e52aa9ffefd1d2ca 427 Gene3D G3DSA:1.10.287.130 193 262 5.7E-6 T 28-03-2018 CU254_RS03375 521ae48b4f40e182e52aa9ffefd1d2ca 427 SMART SM00304 149 201 0.0027 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS03375 521ae48b4f40e182e52aa9ffefd1d2ca 427 Gene3D G3DSA:3.30.565.10 267 417 1.1E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS03375 521ae48b4f40e182e52aa9ffefd1d2ca 427 PRINTS PR00344 Bacterial sensor protein C-terminal signature 373 391 8.4E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS03375 521ae48b4f40e182e52aa9ffefd1d2ca 427 PRINTS PR00344 Bacterial sensor protein C-terminal signature 363 373 8.4E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS03375 521ae48b4f40e182e52aa9ffefd1d2ca 427 PRINTS PR00344 Bacterial sensor protein C-terminal signature 345 359 8.4E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS03375 521ae48b4f40e182e52aa9ffefd1d2ca 427 SMART SM00387 308 411 7.3E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS31285 3641f8c3fb171f5641ffa60e0a9cf6f9 84 SUPERFAMILY SSF81333 21 82 2.48E-14 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CU254_RS31285 3641f8c3fb171f5641ffa60e0a9cf6f9 84 Hamap MF_01396 ATP synthase subunit c [atpH]. 18 83 13.182 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CU254_RS31285 3641f8c3fb171f5641ffa60e0a9cf6f9 84 PRINTS PR00124 ATP synthase C subunit signature 58 83 3.8E-14 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CU254_RS31285 3641f8c3fb171f5641ffa60e0a9cf6f9 84 PRINTS PR00124 ATP synthase C subunit signature 41 56 3.8E-14 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CU254_RS31285 3641f8c3fb171f5641ffa60e0a9cf6f9 84 PRINTS PR00124 ATP synthase C subunit signature 20 39 3.8E-14 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CU254_RS31285 3641f8c3fb171f5641ffa60e0a9cf6f9 84 Pfam PF00137 ATP synthase subunit C 21 81 1.9E-9 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CU254_RS31285 3641f8c3fb171f5641ffa60e0a9cf6f9 84 Gene3D G3DSA:1.20.20.10 4 83 5.9E-16 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CU254_RS19810 b5dee58c39275e0ceeecc7f83a317fe4 186 Gene3D G3DSA:1.10.10.60 7 62 4.0E-15 T 28-03-2018 CU254_RS19810 b5dee58c39275e0ceeecc7f83a317fe4 186 SUPERFAMILY SSF48498 80 184 6.92E-12 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS19810 b5dee58c39275e0ceeecc7f83a317fe4 186 Gene3D G3DSA:1.10.357.10 63 186 7.8E-25 T 28-03-2018 CU254_RS19810 b5dee58c39275e0ceeecc7f83a317fe4 186 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 1.0E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS19810 b5dee58c39275e0ceeecc7f83a317fe4 186 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 1.0E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS19810 b5dee58c39275e0ceeecc7f83a317fe4 186 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 57 8.3E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS19810 b5dee58c39275e0ceeecc7f83a317fe4 186 SUPERFAMILY SSF46689 6 75 2.89E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS30400 f3caa253ddf141add91a48ba9ca6d63a 149 Gene3D G3DSA:1.10.260.40 9 102 7.3E-15 T 28-03-2018 CU254_RS30400 f3caa253ddf141add91a48ba9ca6d63a 149 SUPERFAMILY SSF47413 48 88 1.38E-6 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS30400 f3caa253ddf141add91a48ba9ca6d63a 149 Pfam PF01381 Helix-turn-helix 32 85 2.1E-6 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS08465 4a98f28170f89b273bd6d41b9a05d208 723 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 373 671 3.5E-87 T 28-03-2018 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal CU254_RS08465 4a98f28170f89b273bd6d41b9a05d208 723 Gene3D G3DSA:3.40.630.30 429 668 2.7E-6 T 28-03-2018 CU254_RS08465 4a98f28170f89b273bd6d41b9a05d208 723 SUPERFAMILY SSF144091 31 189 1.44E-5 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CU254_RS08465 4a98f28170f89b273bd6d41b9a05d208 723 SUPERFAMILY SSF55729 480 669 7.95E-5 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS08465 4a98f28170f89b273bd6d41b9a05d208 723 Gene3D G3DSA:1.20.1540.10 24 217 4.4E-8 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CU254_RS25760 b0f4defc136415b74ffae4a797357fab 334 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 3 218 1.3E-49 T 28-03-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 CU254_RS25760 b0f4defc136415b74ffae4a797357fab 334 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 226 325 8.2E-21 T 28-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal CU254_RS25760 b0f4defc136415b74ffae4a797357fab 334 Gene3D G3DSA:3.30.465.10 135 219 3.5E-16 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CU254_RS25760 b0f4defc136415b74ffae4a797357fab 334 Gene3D G3DSA:3.30.465.10 57 130 9.6E-17 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CU254_RS25760 b0f4defc136415b74ffae4a797357fab 334 Gene3D G3DSA:3.30.43.10 1 51 5.4E-20 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CU254_RS25760 b0f4defc136415b74ffae4a797357fab 334 SUPERFAMILY SSF56176 1 218 4.36E-59 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CU254_RS25760 b0f4defc136415b74ffae4a797357fab 334 Gene3D G3DSA:3.30.390.50 221 334 1.6E-28 T 28-03-2018 CU254_RS25760 b0f4defc136415b74ffae4a797357fab 334 SUPERFAMILY SSF55447 224 327 1.07E-28 T 28-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal CU254_RS25760 b0f4defc136415b74ffae4a797357fab 334 SMART SM01092 225 327 4.0E-31 T 28-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal CU254_RS06140 ddac3a87d719e7d80ba96de9bfef36a8 351 Gene3D G3DSA:3.40.190.10 143 330 2.1E-32 T 28-03-2018 CU254_RS06140 ddac3a87d719e7d80ba96de9bfef36a8 351 Gene3D G3DSA:3.40.190.10 39 142 1.3E-12 T 28-03-2018 CU254_RS06140 ddac3a87d719e7d80ba96de9bfef36a8 351 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 44 330 1.1E-57 T 28-03-2018 IPR010067 Aliphatic sulfonates-binding protein GO:0016020|GO:0042626 CU254_RS06140 ddac3a87d719e7d80ba96de9bfef36a8 351 SUPERFAMILY SSF53850 43 266 1.26E-41 T 28-03-2018 CU254_RS06140 ddac3a87d719e7d80ba96de9bfef36a8 351 Pfam PF13379 NMT1-like family 42 268 2.5E-32 T 28-03-2018 CU254_RS05205 0f44adfea67904388b5a3b0bc1e91332 316 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 310 4.0E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS05205 0f44adfea67904388b5a3b0bc1e91332 316 Gene3D G3DSA:1.10.3720.10 87 315 2.4E-41 T 28-03-2018 CU254_RS05205 0f44adfea67904388b5a3b0bc1e91332 316 SUPERFAMILY SSF160964 38 83 1.57E-5 T 28-03-2018 CU254_RS05205 0f44adfea67904388b5a3b0bc1e91332 316 Gene3D G3DSA:1.20.58.370 22 71 6.8E-9 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain CU254_RS05205 0f44adfea67904388b5a3b0bc1e91332 316 SUPERFAMILY SSF161098 81 307 5.23E-58 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS28405 48bf1904a7af32d47433b01c3442d5c0 548 Gene3D G3DSA:3.20.20.140 180 499 3.1E-53 T 28-03-2018 CU254_RS28405 48bf1904a7af32d47433b01c3442d5c0 548 Gene3D G3DSA:2.30.40.10 5 111 5.5E-14 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS28405 48bf1904a7af32d47433b01c3442d5c0 548 SUPERFAMILY SSF51556 57 116 1.27E-31 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS28405 48bf1904a7af32d47433b01c3442d5c0 548 SUPERFAMILY SSF51556 192 262 1.27E-31 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS28405 48bf1904a7af32d47433b01c3442d5c0 548 SUPERFAMILY SSF51556 293 502 1.27E-31 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS28405 48bf1904a7af32d47433b01c3442d5c0 548 SUPERFAMILY SSF51338 3 58 3.78E-15 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS28405 48bf1904a7af32d47433b01c3442d5c0 548 SUPERFAMILY SSF51338 501 545 3.78E-15 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS28405 48bf1904a7af32d47433b01c3442d5c0 548 Pfam PF07969 Amidohydrolase family 47 542 2.8E-87 T 28-03-2018 IPR013108 Amidohydrolase 3 CU254_RS11730 cfa77b7c8daa37f8a1258b98f3822ef4 370 ProSitePatterns PS01054 Transaldolase signature 1. 42 50 - T 28-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 CU254_RS11730 cfa77b7c8daa37f8a1258b98f3822ef4 370 SUPERFAMILY SSF51569 7 364 3.66E-79 T 28-03-2018 CU254_RS11730 cfa77b7c8daa37f8a1258b98f3822ef4 370 Gene3D G3DSA:3.20.20.70 2 362 1.5E-132 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS11730 cfa77b7c8daa37f8a1258b98f3822ef4 370 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 16 360 2.8E-84 T 28-03-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 CU254_RS11730 cfa77b7c8daa37f8a1258b98f3822ef4 370 PIRSF PIRSF036915 1 370 3.7E-169 T 28-03-2018 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CU254_RS11730 cfa77b7c8daa37f8a1258b98f3822ef4 370 ProSitePatterns PS00958 Transaldolase active site. 138 155 - T 28-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 CU254_RS11730 cfa77b7c8daa37f8a1258b98f3822ef4 370 TIGRFAM TIGR00876 tal_mycobact: transaldolase 12 359 3.5E-137 T 28-03-2018 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CU254_RS11730 cfa77b7c8daa37f8a1258b98f3822ef4 370 Hamap MF_00493 Transaldolase [tal]. 1 370 155.787 T 28-03-2018 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CU254_RS38040 c4cf96c3f3092caa906a48b43d031858 489 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 8 222 1.7E-17 T 28-03-2018 CU254_RS38040 c4cf96c3f3092caa906a48b43d031858 489 Gene3D G3DSA:3.50.50.60 4 161 1.3E-35 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS38040 c4cf96c3f3092caa906a48b43d031858 489 SUPERFAMILY SSF51905 293 409 1.7E-56 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS38040 c4cf96c3f3092caa906a48b43d031858 489 SUPERFAMILY SSF51905 5 226 1.7E-56 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS38040 c4cf96c3f3092caa906a48b43d031858 489 PRINTS PR00419 Adrenodoxin reductase family signature 224 237 5.7E-6 T 28-03-2018 CU254_RS38040 c4cf96c3f3092caa906a48b43d031858 489 PRINTS PR00419 Adrenodoxin reductase family signature 6 28 5.7E-6 T 28-03-2018 CU254_RS38040 c4cf96c3f3092caa906a48b43d031858 489 PRINTS PR00419 Adrenodoxin reductase family signature 173 187 5.7E-6 T 28-03-2018 CU254_RS38040 c4cf96c3f3092caa906a48b43d031858 489 Gene3D G3DSA:3.50.50.60 162 487 1.1E-55 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS26880 881c75f595d667b1dc25015eccb786c9 1111 SUPERFAMILY SSF56300 766 1005 8.81E-29 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CU254_RS26880 881c75f595d667b1dc25015eccb786c9 1111 Gene3D G3DSA:2.60.120.430 596 754 4.0E-28 T 28-03-2018 CU254_RS26880 881c75f595d667b1dc25015eccb786c9 1111 Pfam PF09992 Phosphodiester glycosidase 225 396 1.8E-31 T 28-03-2018 IPR018711 Phosphodiester glycosidase CU254_RS26880 881c75f595d667b1dc25015eccb786c9 1111 Gene3D G3DSA:3.60.21.10 765 1022 3.3E-28 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CU254_RS26880 881c75f595d667b1dc25015eccb786c9 1111 Pfam PF00149 Calcineurin-like phosphoesterase 768 935 3.9E-12 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CU254_RS26880 881c75f595d667b1dc25015eccb786c9 1111 Gene3D G3DSA:2.60.40.1080 1023 1111 1.5E-10 T 28-03-2018 CU254_RS03620 9e655bc390259be53c02feec423e57b1 319 SMART SM00880 42 302 1.9E-49 T 28-03-2018 IPR007899 CHAD domain CU254_RS03620 9e655bc390259be53c02feec423e57b1 319 Pfam PF05235 CHAD domain 43 271 4.3E-52 T 28-03-2018 IPR007899 CHAD domain CU254_RS25135 0e9f20d778e4744fdef6dc368bfffdcd 288 Gene3D G3DSA:3.40.190.10 90 172 6.3E-17 T 28-03-2018 CU254_RS25135 0e9f20d778e4744fdef6dc368bfffdcd 288 Gene3D G3DSA:3.40.190.10 173 254 4.7E-15 T 28-03-2018 CU254_RS25135 0e9f20d778e4744fdef6dc368bfffdcd 288 Gene3D G3DSA:1.10.10.10 1 87 1.6E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS25135 0e9f20d778e4744fdef6dc368bfffdcd 288 Pfam PF03466 LysR substrate binding domain 86 276 9.1E-33 T 28-03-2018 IPR005119 LysR, substrate-binding CU254_RS25135 0e9f20d778e4744fdef6dc368bfffdcd 288 SUPERFAMILY SSF53850 87 282 5.27E-31 T 28-03-2018 CU254_RS25135 0e9f20d778e4744fdef6dc368bfffdcd 288 SUPERFAMILY SSF46785 1 110 9.17E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS25135 0e9f20d778e4744fdef6dc368bfffdcd 288 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 8.6E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS25135 0e9f20d778e4744fdef6dc368bfffdcd 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.1E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS25135 0e9f20d778e4744fdef6dc368bfffdcd 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.1E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS25135 0e9f20d778e4744fdef6dc368bfffdcd 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.1E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS19590 67b9c74a2ff35fb32d506ae0244070e1 212 SUPERFAMILY SSF48498 90 195 1.14E-17 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS19590 67b9c74a2ff35fb32d506ae0244070e1 212 SUPERFAMILY SSF46689 14 94 1.4E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS19590 67b9c74a2ff35fb32d506ae0244070e1 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 71 4.1E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS19590 67b9c74a2ff35fb32d506ae0244070e1 212 Gene3D G3DSA:1.10.357.10 9 206 1.1E-31 T 28-03-2018 CU254_RS38570 c64bb84f93c7c115ebc589cd701067ae 401 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 41 388 4.1E-130 T 28-03-2018 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 CU254_RS38570 c64bb84f93c7c115ebc589cd701067ae 401 Pfam PF00676 Dehydrogenase E1 component 74 349 2.6E-73 T 28-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 CU254_RS38570 c64bb84f93c7c115ebc589cd701067ae 401 SUPERFAMILY SSF52518 38 390 1.16E-97 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS38570 c64bb84f93c7c115ebc589cd701067ae 401 Gene3D G3DSA:3.40.50.970 15 388 8.5E-90 T 28-03-2018 CU254_RS36765 ecfc617fc1048208ca871c0aa49299d7 224 Pfam PF00027 Cyclic nucleotide-binding domain 29 114 1.5E-22 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CU254_RS36765 ecfc617fc1048208ca871c0aa49299d7 224 SUPERFAMILY SSF51206 4 142 1.57E-35 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like CU254_RS36765 ecfc617fc1048208ca871c0aa49299d7 224 SMART SM00100 10 128 8.9E-25 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CU254_RS36765 ecfc617fc1048208ca871c0aa49299d7 224 Gene3D G3DSA:1.10.10.10 144 224 5.9E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS36765 ecfc617fc1048208ca871c0aa49299d7 224 Gene3D G3DSA:2.60.120.10 1 143 1.1E-34 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS36765 ecfc617fc1048208ca871c0aa49299d7 224 Pfam PF13545 Crp-like helix-turn-helix domain 148 221 3.3E-19 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CU254_RS36765 ecfc617fc1048208ca871c0aa49299d7 224 SMART SM00419 167 215 8.6E-14 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CU254_RS36765 ecfc617fc1048208ca871c0aa49299d7 224 SUPERFAMILY SSF46785 145 223 3.33E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS33395 b78daa3f946666b6d173ebfa78a7cc00 297 SUPERFAMILY SSF55729 54 148 1.68E-7 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS33395 b78daa3f946666b6d173ebfa78a7cc00 297 Gene3D G3DSA:3.40.630.30 5 193 8.6E-9 T 28-03-2018 CU254_RS41045 8f37a51834fcf74a920b546f36769959 192 Gene3D G3DSA:3.40.50.300 1 144 2.9E-15 T 28-03-2018 CU254_RS41045 8f37a51834fcf74a920b546f36769959 192 Pfam PF13671 AAA domain 3 141 1.9E-13 T 28-03-2018 CU254_RS41045 8f37a51834fcf74a920b546f36769959 192 SUPERFAMILY SSF52540 1 172 3.85E-15 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS27445 10c0158fe71e763f235b14b16ea786e8 388 SUPERFAMILY SSF103473 3 380 4.05E-51 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS27445 10c0158fe71e763f235b14b16ea786e8 388 Gene3D G3DSA:1.20.1250.20 2 183 2.9E-25 T 28-03-2018 CU254_RS27445 10c0158fe71e763f235b14b16ea786e8 388 Gene3D G3DSA:1.20.1250.20 184 383 4.1E-17 T 28-03-2018 CU254_RS27445 10c0158fe71e763f235b14b16ea786e8 388 Pfam PF07690 Major Facilitator Superfamily 7 315 1.1E-32 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS22785 95defc9a1f306f313992bfa0b57fba19 251 Pfam PF13578 Methyltransferase domain 66 157 1.2E-15 T 28-03-2018 CU254_RS22785 95defc9a1f306f313992bfa0b57fba19 251 Gene3D G3DSA:3.40.50.150 27 213 1.4E-13 T 28-03-2018 CU254_RS22785 95defc9a1f306f313992bfa0b57fba19 251 SUPERFAMILY SSF53335 42 149 1.55E-15 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS21170 d378cfbeca6a9dc8be2a292c1ca9aba5 116 SUPERFAMILY SSF52091 7 94 1.51E-10 T 28-03-2018 IPR002645 STAS domain CU254_RS21170 d378cfbeca6a9dc8be2a292c1ca9aba5 116 Gene3D G3DSA:3.30.750.24 3 96 3.5E-10 T 28-03-2018 IPR002645 STAS domain CU254_RS21170 d378cfbeca6a9dc8be2a292c1ca9aba5 116 Pfam PF13466 STAS domain 13 93 8.7E-9 T 28-03-2018 IPR002645 STAS domain CU254_RS14240 1f82fc084b0d3612d2b30f354940e2cc 235 SUPERFAMILY SSF50494 51 232 1.18E-33 T 28-03-2018 IPR009003 Peptidase S1, PA clan CU254_RS14240 1f82fc084b0d3612d2b30f354940e2cc 235 Gene3D G3DSA:2.40.10.10 21 60 1.0E-7 T 28-03-2018 CU254_RS14240 1f82fc084b0d3612d2b30f354940e2cc 235 Gene3D G3DSA:2.40.10.10 116 234 1.0E-15 T 28-03-2018 CU254_RS14240 1f82fc084b0d3612d2b30f354940e2cc 235 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 187 199 8.2E-8 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CU254_RS14240 1f82fc084b0d3612d2b30f354940e2cc 235 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 104 118 8.2E-8 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CU254_RS14240 1f82fc084b0d3612d2b30f354940e2cc 235 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 57 72 8.2E-8 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CU254_RS14240 1f82fc084b0d3612d2b30f354940e2cc 235 SMART SM00020 32 229 2.7E-14 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CU254_RS14240 1f82fc084b0d3612d2b30f354940e2cc 235 Gene3D G3DSA:2.40.10.10 61 115 1.5E-15 T 28-03-2018 CU254_RS14240 1f82fc084b0d3612d2b30f354940e2cc 235 Pfam PF00089 Trypsin 46 229 2.5E-24 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CU254_RS36200 c04bfc60ca6cad0b066d3b81aaac752f 481 Pfam PF01433 Peptidase family M1 domain 321 459 1.5E-19 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CU254_RS36200 c04bfc60ca6cad0b066d3b81aaac752f 481 SUPERFAMILY SSF55486 251 466 1.18E-41 T 28-03-2018 CU254_RS36200 c04bfc60ca6cad0b066d3b81aaac752f 481 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 323 338 4.9E-5 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CU254_RS36200 c04bfc60ca6cad0b066d3b81aaac752f 481 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 177 192 4.9E-5 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CU254_RS36200 c04bfc60ca6cad0b066d3b81aaac752f 481 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 342 354 4.9E-5 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CU254_RS36200 c04bfc60ca6cad0b066d3b81aaac752f 481 Gene3D G3DSA:2.60.40.1730 55 242 5.3E-33 T 28-03-2018 CU254_RS36200 c04bfc60ca6cad0b066d3b81aaac752f 481 SUPERFAMILY SSF63737 46 239 4.45E-27 T 28-03-2018 CU254_RS36200 c04bfc60ca6cad0b066d3b81aaac752f 481 Gene3D G3DSA:1.10.390.10 314 463 1.0E-29 T 28-03-2018 CU254_RS04400 8d9d11acda469c57526863554f4ce16a 314 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 37 45 1.0E-13 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CU254_RS04400 8d9d11acda469c57526863554f4ce16a 314 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 108 122 1.0E-13 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CU254_RS04400 8d9d11acda469c57526863554f4ce16a 314 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 63 74 1.0E-13 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CU254_RS04400 8d9d11acda469c57526863554f4ce16a 314 Gene3D G3DSA:3.40.50.1820 1 313 5.6E-59 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS04400 8d9d11acda469c57526863554f4ce16a 314 TIGRFAM TIGR01249 pro_imino_pep_1: prolyl aminopeptidase 13 312 2.1E-112 T 28-03-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 CU254_RS04400 8d9d11acda469c57526863554f4ce16a 314 SUPERFAMILY SSF53474 2 297 3.74E-57 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS04400 8d9d11acda469c57526863554f4ce16a 314 PRINTS PR00111 Alpha/beta hydrolase fold signature 108 121 9.2E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS04400 8d9d11acda469c57526863554f4ce16a 314 PRINTS PR00111 Alpha/beta hydrolase fold signature 60 75 9.2E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS04400 8d9d11acda469c57526863554f4ce16a 314 PRINTS PR00111 Alpha/beta hydrolase fold signature 122 135 9.2E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS04400 8d9d11acda469c57526863554f4ce16a 314 PIRSF PIRSF006431 1 314 9.3E-127 T 28-03-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 CU254_RS04400 8d9d11acda469c57526863554f4ce16a 314 Pfam PF00561 alpha/beta hydrolase fold 35 297 1.4E-28 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS28110 e15b30e7bddab1aac7e3b8970986a9a2 357 SMART SM00839 144 353 1.1E-37 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CU254_RS28110 e15b30e7bddab1aac7e3b8970986a9a2 357 Gene3D G3DSA:3.40.50.720 143 338 1.9E-30 T 28-03-2018 CU254_RS28110 e15b30e7bddab1aac7e3b8970986a9a2 357 PIRSF PIRSF000188 5 355 1.4E-138 T 28-03-2018 IPR016211 Glutamate/phenylalanine/leucine/valine dehydrogenase, bacterial/archaeal GO:0016639|GO:0055114 CU254_RS28110 e15b30e7bddab1aac7e3b8970986a9a2 357 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 218 294 1.4E-8 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CU254_RS28110 e15b30e7bddab1aac7e3b8970986a9a2 357 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 74 87 - T 28-03-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CU254_RS28110 e15b30e7bddab1aac7e3b8970986a9a2 357 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 13 131 5.0E-28 T 28-03-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CU254_RS28110 e15b30e7bddab1aac7e3b8970986a9a2 357 SUPERFAMILY SSF53223 10 144 4.48E-46 T 28-03-2018 CU254_RS28110 e15b30e7bddab1aac7e3b8970986a9a2 357 SUPERFAMILY SSF51735 141 352 7.3E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS28110 e15b30e7bddab1aac7e3b8970986a9a2 357 Gene3D G3DSA:3.40.50.10860 7 142 1.0E-51 T 28-03-2018 CU254_RS28110 e15b30e7bddab1aac7e3b8970986a9a2 357 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 66 80 2.6E-18 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CU254_RS28110 e15b30e7bddab1aac7e3b8970986a9a2 357 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 176 196 2.6E-18 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CU254_RS28110 e15b30e7bddab1aac7e3b8970986a9a2 357 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 132 154 2.6E-18 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CU254_RS28110 e15b30e7bddab1aac7e3b8970986a9a2 357 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 288 299 2.6E-18 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CU254_RS17195 6a42d35534cf0ca55c4632e97f606c89 141 SUPERFAMILY SSF49503 50 139 1.42E-22 T 28-03-2018 IPR008972 Cupredoxin CU254_RS17195 6a42d35534cf0ca55c4632e97f606c89 141 Gene3D G3DSA:2.60.40.420 40 140 1.7E-13 T 28-03-2018 IPR008972 Cupredoxin CU254_RS17195 6a42d35534cf0ca55c4632e97f606c89 141 Pfam PF13473 Cupredoxin-like domain 51 139 9.0E-12 T 28-03-2018 IPR028096 EfeO-type cupredoxin-like domain CU254_RS17195 6a42d35534cf0ca55c4632e97f606c89 141 PRINTS PR00155 Amicyanin family signature 108 123 1.0E-8 T 28-03-2018 IPR002386 Amicyanin/Pseudoazurin GO:0005507|GO:0009055 CU254_RS17195 6a42d35534cf0ca55c4632e97f606c89 141 PRINTS PR00155 Amicyanin family signature 124 139 1.0E-8 T 28-03-2018 IPR002386 Amicyanin/Pseudoazurin GO:0005507|GO:0009055 CU254_RS17195 6a42d35534cf0ca55c4632e97f606c89 141 PRINTS PR00155 Amicyanin family signature 68 87 1.0E-8 T 28-03-2018 IPR002386 Amicyanin/Pseudoazurin GO:0005507|GO:0009055 CU254_RS23910 d7ef05bca25232e5cee19e5846e11295 383 Gene3D G3DSA:3.40.47.10 263 380 2.4E-30 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS23910 d7ef05bca25232e5cee19e5846e11295 383 PIRSF PIRSF000429 2 383 8.5E-118 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CU254_RS23910 d7ef05bca25232e5cee19e5846e11295 383 Pfam PF02803 Thiolase, C-terminal domain 261 382 2.2E-44 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CU254_RS23910 d7ef05bca25232e5cee19e5846e11295 383 Gene3D G3DSA:3.40.47.10 2 262 1.2E-49 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS23910 d7ef05bca25232e5cee19e5846e11295 383 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 381 2.8E-122 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CU254_RS23910 d7ef05bca25232e5cee19e5846e11295 383 Pfam PF00108 Thiolase, N-terminal domain 5 252 6.2E-58 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CU254_RS23910 d7ef05bca25232e5cee19e5846e11295 383 SUPERFAMILY SSF53901 261 382 1.38E-42 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS23910 d7ef05bca25232e5cee19e5846e11295 383 SUPERFAMILY SSF53901 3 260 6.01E-67 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS23910 d7ef05bca25232e5cee19e5846e11295 383 ProSitePatterns PS00737 Thiolases signature 2. 329 345 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CU254_RS17295 e12d5edcf9173fc33c0586f9f2d6ea65 231 Pfam PF05988 Bacterial protein of unknown function (DUF899) 15 224 2.1E-52 T 28-03-2018 IPR010296 Protein of unknown function DUF899, thioredoxin-like CU254_RS17295 e12d5edcf9173fc33c0586f9f2d6ea65 231 Gene3D G3DSA:3.40.30.10 24 206 5.8E-6 T 28-03-2018 CU254_RS25160 a89ea68b4ed4e38ce858f27a3ad3d981 174 Gene3D G3DSA:1.10.287.1060 53 155 3.0E-5 T 28-03-2018 CU254_RS00735 9c4acbec748e91c9325b4ed40e061368 284 Gene3D G3DSA:1.10.260.40 1 87 7.8E-15 T 28-03-2018 CU254_RS00735 9c4acbec748e91c9325b4ed40e061368 284 SUPERFAMILY SSF47413 7 67 8.45E-12 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS00735 9c4acbec748e91c9325b4ed40e061368 284 SMART SM00530 15 70 2.7E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS00735 9c4acbec748e91c9325b4ed40e061368 284 Pfam PF13560 Helix-turn-helix domain 11 73 2.1E-14 T 28-03-2018 CU254_RS06550 acbd0ddd7cafe95383046f62892cfb0f 196 SUPERFAMILY SSF51182 70 180 5.86E-27 T 28-03-2018 IPR011051 RmlC-like cupin domain CU254_RS06550 acbd0ddd7cafe95383046f62892cfb0f 196 Pfam PF07883 Cupin domain 111 180 4.1E-17 T 28-03-2018 IPR013096 Cupin 2, conserved barrel CU254_RS06550 acbd0ddd7cafe95383046f62892cfb0f 196 SMART SM00530 18 73 2.1E-17 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS06550 acbd0ddd7cafe95383046f62892cfb0f 196 SUPERFAMILY SSF47413 10 80 6.76E-19 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS06550 acbd0ddd7cafe95383046f62892cfb0f 196 Gene3D G3DSA:1.10.260.40 4 71 5.1E-19 T 28-03-2018 CU254_RS06550 acbd0ddd7cafe95383046f62892cfb0f 196 Pfam PF01381 Helix-turn-helix 19 73 8.2E-16 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS06550 acbd0ddd7cafe95383046f62892cfb0f 196 Gene3D G3DSA:2.60.120.10 72 193 4.7E-26 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS41975 ed21f5e235610adde4ba5a311b8e82e8 217 Gene3D G3DSA:3.20.20.70 9 208 5.8E-4 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS21300 f9ca61a2661878f11fb09a782ea5be59 211 SUPERFAMILY SSF142695 11 174 3.14E-52 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CU254_RS21300 f9ca61a2661878f11fb09a782ea5be59 211 Pfam PF00925 GTP cyclohydrolase II 11 173 2.3E-58 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CU254_RS21300 f9ca61a2661878f11fb09a782ea5be59 211 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 2 200 35.182 T 28-03-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CU254_RS24700 19b0bef81fef3176acbafa57301e9bbd 190 Gene3D G3DSA:3.40.630.30 5 186 9.0E-37 T 28-03-2018 CU254_RS24700 19b0bef81fef3176acbafa57301e9bbd 190 SUPERFAMILY SSF55729 6 178 1.87E-44 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS24700 19b0bef81fef3176acbafa57301e9bbd 190 Pfam PF13302 Acetyltransferase (GNAT) domain 12 154 9.1E-32 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS37465 e1287cf220730fe4c4c6ccac07ea2d42 144 Gene3D G3DSA:3.40.30.10 41 101 1.2E-10 T 28-03-2018 CU254_RS37465 e1287cf220730fe4c4c6ccac07ea2d42 144 SUPERFAMILY SSF52833 44 140 2.39E-16 T 28-03-2018 IPR012336 Thioredoxin-like fold CU254_RS37465 e1287cf220730fe4c4c6ccac07ea2d42 144 Pfam PF00085 Thioredoxin 51 124 2.1E-7 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 CU254_RS37465 e1287cf220730fe4c4c6ccac07ea2d42 144 Gene3D G3DSA:3.40.30.10 102 143 0.054 T 28-03-2018 CU254_RS19490 eaa4111afc3fdcbb3387a11a5a4a35c1 550 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 514 546 0.0022 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CU254_RS19490 eaa4111afc3fdcbb3387a11a5a4a35c1 550 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 267 0.022 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CU254_RS19490 eaa4111afc3fdcbb3387a11a5a4a35c1 550 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS19490 eaa4111afc3fdcbb3387a11a5a4a35c1 550 Pfam PF00005 ABC transporter 25 183 4.2E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS19490 eaa4111afc3fdcbb3387a11a5a4a35c1 550 Pfam PF00005 ABC transporter 314 463 2.6E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS19490 eaa4111afc3fdcbb3387a11a5a4a35c1 550 ProSitePatterns PS00211 ABC transporters family signature. 435 449 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS19490 eaa4111afc3fdcbb3387a11a5a4a35c1 550 SUPERFAMILY SSF52540 4 254 5.9E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS19490 eaa4111afc3fdcbb3387a11a5a4a35c1 550 SMART SM00382 33 240 8.4E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS19490 eaa4111afc3fdcbb3387a11a5a4a35c1 550 SMART SM00382 322 512 3.4E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS19490 eaa4111afc3fdcbb3387a11a5a4a35c1 550 Gene3D G3DSA:3.40.50.300 289 550 2.6E-67 T 28-03-2018 CU254_RS19490 eaa4111afc3fdcbb3387a11a5a4a35c1 550 Gene3D G3DSA:3.40.50.300 1 283 1.9E-64 T 28-03-2018 CU254_RS19490 eaa4111afc3fdcbb3387a11a5a4a35c1 550 SUPERFAMILY SSF52540 292 534 4.24E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS33550 7231d65c1b53f2a68cef50dbb1e65f4d 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 3.1E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS33550 7231d65c1b53f2a68cef50dbb1e65f4d 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 3.1E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS33550 7231d65c1b53f2a68cef50dbb1e65f4d 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 3.1E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS33550 7231d65c1b53f2a68cef50dbb1e65f4d 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 3.1E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS33550 7231d65c1b53f2a68cef50dbb1e65f4d 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 3.1E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS33550 7231d65c1b53f2a68cef50dbb1e65f4d 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 3.1E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS33550 7231d65c1b53f2a68cef50dbb1e65f4d 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 241 6.3E-48 T 28-03-2018 CU254_RS33550 7231d65c1b53f2a68cef50dbb1e65f4d 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 5.0E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS33550 7231d65c1b53f2a68cef50dbb1e65f4d 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 128 136 5.0E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS33550 7231d65c1b53f2a68cef50dbb1e65f4d 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 5.0E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS33550 7231d65c1b53f2a68cef50dbb1e65f4d 245 SUPERFAMILY SSF51735 8 242 3.71E-67 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS33550 7231d65c1b53f2a68cef50dbb1e65f4d 245 Gene3D G3DSA:3.40.50.720 2 243 1.1E-64 T 28-03-2018 CU254_RS11870 79ecd44fec591d8a75c7a5840d7f95b8 559 SUPERFAMILY SSF54631 256 393 6.73E-5 T 28-03-2018 CU254_RS11870 79ecd44fec591d8a75c7a5840d7f95b8 559 SUPERFAMILY SSF55073 390 505 5.96E-14 T 28-03-2018 IPR029787 Nucleotide cyclase CU254_RS11870 79ecd44fec591d8a75c7a5840d7f95b8 559 Gene3D G3DSA:3.10.580.10 246 378 9.8E-4 T 28-03-2018 CU254_RS11870 79ecd44fec591d8a75c7a5840d7f95b8 559 Gene3D G3DSA:3.20.20.450 3 232 4.7E-45 T 28-03-2018 IPR001633 EAL domain CU254_RS11870 79ecd44fec591d8a75c7a5840d7f95b8 559 Gene3D G3DSA:3.30.70.270 379 526 6.6E-18 T 28-03-2018 CU254_RS11870 79ecd44fec591d8a75c7a5840d7f95b8 559 SUPERFAMILY SSF141868 7 227 3.01E-42 T 28-03-2018 IPR001633 EAL domain CU254_RS11870 79ecd44fec591d8a75c7a5840d7f95b8 559 SMART SM00267 374 536 1.6E-6 T 28-03-2018 IPR000160 GGDEF domain CU254_RS11870 79ecd44fec591d8a75c7a5840d7f95b8 559 Pfam PF00990 Diguanylate cyclase, GGDEF domain 390 471 4.3E-10 T 28-03-2018 IPR000160 GGDEF domain CU254_RS11870 79ecd44fec591d8a75c7a5840d7f95b8 559 Pfam PF00563 EAL domain 7 223 2.9E-41 T 28-03-2018 IPR001633 EAL domain CU254_RS11870 79ecd44fec591d8a75c7a5840d7f95b8 559 SMART SM00052 5 228 3.7E-15 T 28-03-2018 IPR001633 EAL domain CU254_RS22490 c76df21a8811c55f1c5a29f866fc3dff 241 Gene3D G3DSA:3.40.1280.10 89 241 5.0E-44 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CU254_RS22490 c76df21a8811c55f1c5a29f866fc3dff 241 SUPERFAMILY SSF75217 71 238 4.38E-43 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CU254_RS22490 c76df21a8811c55f1c5a29f866fc3dff 241 SMART SM00967 14 83 4.7E-13 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CU254_RS22490 c76df21a8811c55f1c5a29f866fc3dff 241 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 14 78 1.4E-7 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CU254_RS22490 c76df21a8811c55f1c5a29f866fc3dff 241 SUPERFAMILY SSF55315 1 80 8.59E-14 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CU254_RS22490 c76df21a8811c55f1c5a29f866fc3dff 241 Pfam PF00588 SpoU rRNA Methylase family 93 233 7.3E-37 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CU254_RS22490 c76df21a8811c55f1c5a29f866fc3dff 241 Gene3D G3DSA:3.30.1330.30 1 83 1.8E-18 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CU254_RS29740 c470019be5f432aa837efc0938f08736 265 Pfam PF04542 Sigma-70 region 2 38 106 1.2E-8 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS29740 c470019be5f432aa837efc0938f08736 265 Gene3D G3DSA:1.10.10.10 138 247 2.5E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS29740 c470019be5f432aa837efc0938f08736 265 SUPERFAMILY SSF88946 16 112 1.02E-15 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS29740 c470019be5f432aa837efc0938f08736 265 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 37 189 5.9E-14 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS29740 c470019be5f432aa837efc0938f08736 265 Pfam PF13490 Putative zinc-finger 203 236 7.5E-8 T 28-03-2018 IPR027383 Putative zinc-finger CU254_RS29740 c470019be5f432aa837efc0938f08736 265 SUPERFAMILY SSF88659 124 189 1.64E-8 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS29740 c470019be5f432aa837efc0938f08736 265 Gene3D G3DSA:1.10.1740.10 14 112 5.1E-16 T 28-03-2018 CU254_RS10920 af009c574bb340af52ee8fcc7aa7864f 396 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 380 390 - T 28-03-2018 IPR030391 RNA methyltransferase TrmA, conserved site CU254_RS10920 af009c574bb340af52ee8fcc7aa7864f 396 SUPERFAMILY SSF53335 70 395 2.15E-51 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS10920 af009c574bb340af52ee8fcc7aa7864f 396 SUPERFAMILY SSF50249 6 53 7.42E-11 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CU254_RS10920 af009c574bb340af52ee8fcc7aa7864f 396 Gene3D G3DSA:3.40.50.150 77 396 7.7E-44 T 28-03-2018 CU254_RS10920 af009c574bb340af52ee8fcc7aa7864f 396 Pfam PF01938 TRAM domain 6 53 1.0E-7 T 28-03-2018 IPR002792 TRAM domain CU254_RS10920 af009c574bb340af52ee8fcc7aa7864f 396 Gene3D G3DSA:2.40.50.140 3 76 4.3E-21 T 28-03-2018 CU254_RS10920 af009c574bb340af52ee8fcc7aa7864f 396 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 323 395 3.9E-10 T 28-03-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 CU254_RS20940 75d6506856a9cabef6aa613062d6d4c3 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 8.0E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS20940 75d6506856a9cabef6aa613062d6d4c3 302 Gene3D G3DSA:3.40.190.10 181 271 6.1E-19 T 28-03-2018 CU254_RS20940 75d6506856a9cabef6aa613062d6d4c3 302 SUPERFAMILY SSF53850 92 298 6.03E-32 T 28-03-2018 CU254_RS20940 75d6506856a9cabef6aa613062d6d4c3 302 Gene3D G3DSA:1.10.10.10 2 84 9.7E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS20940 75d6506856a9cabef6aa613062d6d4c3 302 Gene3D G3DSA:3.40.190.10 90 180 3.2E-20 T 28-03-2018 CU254_RS20940 75d6506856a9cabef6aa613062d6d4c3 302 SUPERFAMILY SSF46785 2 112 7.0E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS20940 75d6506856a9cabef6aa613062d6d4c3 302 Pfam PF03466 LysR substrate binding domain 91 295 1.9E-33 T 28-03-2018 IPR005119 LysR, substrate-binding CU254_RS08095 af66c7068256b667935195fe4625bb9b 215 SMART SM00421 148 210 3.5E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS08095 af66c7068256b667935195fe4625bb9b 215 SUPERFAMILY SSF46894 135 197 1.77E-13 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS08095 af66c7068256b667935195fe4625bb9b 215 SMART SM00448 1 120 2.1E-13 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS08095 af66c7068256b667935195fe4625bb9b 215 Gene3D G3DSA:3.40.50.2300 1 131 1.3E-27 T 28-03-2018 CU254_RS08095 af66c7068256b667935195fe4625bb9b 215 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 197 1.8E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS08095 af66c7068256b667935195fe4625bb9b 215 Gene3D G3DSA:1.10.10.10 132 214 1.5E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS08095 af66c7068256b667935195fe4625bb9b 215 SUPERFAMILY SSF52172 1 141 4.84E-22 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS08095 af66c7068256b667935195fe4625bb9b 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 1.2E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS08095 af66c7068256b667935195fe4625bb9b 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 1.2E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS08095 af66c7068256b667935195fe4625bb9b 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 1.2E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS08095 af66c7068256b667935195fe4625bb9b 215 Pfam PF00072 Response regulator receiver domain 3 109 1.0E-15 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS23220 1c3252f3f3d06b789298d84f67b8bb6e 423 Gene3D G3DSA:2.30.40.10 6 77 1.5E-14 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS23220 1c3252f3f3d06b789298d84f67b8bb6e 423 Pfam PF01979 Amidohydrolase family 60 408 7.1E-45 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CU254_RS23220 1c3252f3f3d06b789298d84f67b8bb6e 423 SUPERFAMILY SSF51338 368 416 9.81E-18 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS23220 1c3252f3f3d06b789298d84f67b8bb6e 423 SUPERFAMILY SSF51338 8 64 9.81E-18 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS23220 1c3252f3f3d06b789298d84f67b8bb6e 423 SUPERFAMILY SSF51556 64 368 3.16E-84 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS23220 1c3252f3f3d06b789298d84f67b8bb6e 423 Gene3D G3DSA:3.20.20.140 78 370 1.6E-48 T 28-03-2018 CU254_RS21360 80de5e96685988d5da761e711283173a 202 SUPERFAMILY SSF46689 4 76 3.09E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS21360 80de5e96685988d5da761e711283173a 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 56 8.3E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS21360 80de5e96685988d5da761e711283173a 202 Gene3D G3DSA:1.10.10.60 2 56 3.8E-16 T 28-03-2018 CU254_RS21360 80de5e96685988d5da761e711283173a 202 Gene3D G3DSA:1.10.357.10 57 194 5.6E-23 T 28-03-2018 CU254_RS07200 51bf74adc58461f347a94fb86152b574 265 SUPERFAMILY SSF52768 5 243 2.7E-39 T 28-03-2018 CU254_RS07200 51bf74adc58461f347a94fb86152b574 265 Gene3D G3DSA:3.40.800.10 4 254 6.1E-40 T 28-03-2018 CU254_RS07200 51bf74adc58461f347a94fb86152b574 265 Pfam PF00491 Arginase family 65 243 5.5E-29 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 CU254_RS07200 51bf74adc58461f347a94fb86152b574 265 PRINTS PR00116 Arginase signature 157 175 2.3E-5 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 CU254_RS07200 51bf74adc58461f347a94fb86152b574 265 PRINTS PR00116 Arginase signature 107 134 2.3E-5 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 CU254_RS21685 bebcdf18e02bb63e00dd7d10131dfbe0 478 Gene3D G3DSA:1.20.1250.20 11 200 9.6E-29 T 28-03-2018 CU254_RS21685 bebcdf18e02bb63e00dd7d10131dfbe0 478 SUPERFAMILY SSF103473 14 198 2.88E-59 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS21685 bebcdf18e02bb63e00dd7d10131dfbe0 478 SUPERFAMILY SSF103473 251 461 2.88E-59 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS21685 bebcdf18e02bb63e00dd7d10131dfbe0 478 Gene3D G3DSA:1.20.1250.20 262 474 3.7E-21 T 28-03-2018 CU254_RS21685 bebcdf18e02bb63e00dd7d10131dfbe0 478 PRINTS PR01036 Tetracycline resistance protein TetB signature 141 165 4.7E-8 T 28-03-2018 CU254_RS21685 bebcdf18e02bb63e00dd7d10131dfbe0 478 PRINTS PR01036 Tetracycline resistance protein TetB signature 206 224 4.7E-8 T 28-03-2018 CU254_RS21685 bebcdf18e02bb63e00dd7d10131dfbe0 478 PRINTS PR01036 Tetracycline resistance protein TetB signature 111 131 4.7E-8 T 28-03-2018 CU254_RS21685 bebcdf18e02bb63e00dd7d10131dfbe0 478 PRINTS PR01036 Tetracycline resistance protein TetB signature 19 43 4.7E-8 T 28-03-2018 CU254_RS21685 bebcdf18e02bb63e00dd7d10131dfbe0 478 PRINTS PR01036 Tetracycline resistance protein TetB signature 405 424 4.7E-8 T 28-03-2018 CU254_RS21685 bebcdf18e02bb63e00dd7d10131dfbe0 478 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 20 423 8.4E-77 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CU254_RS21685 bebcdf18e02bb63e00dd7d10131dfbe0 478 ProSitePatterns PS00216 Sugar transport proteins signature 1. 71 88 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CU254_RS21685 bebcdf18e02bb63e00dd7d10131dfbe0 478 Pfam PF07690 Major Facilitator Superfamily 22 312 3.9E-31 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS14105 1e63f2c0e3a4241b96d9423f73d3c3c3 305 SMART SM00829 11 303 6.7E-17 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CU254_RS14105 1e63f2c0e3a4241b96d9423f73d3c3c3 305 Pfam PF00107 Zinc-binding dehydrogenase 156 237 2.2E-10 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CU254_RS14105 1e63f2c0e3a4241b96d9423f73d3c3c3 305 SUPERFAMILY SSF50129 2 150 6.24E-29 T 28-03-2018 IPR011032 GroES-like CU254_RS14105 1e63f2c0e3a4241b96d9423f73d3c3c3 305 SUPERFAMILY SSF51735 118 228 8.75E-25 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS14105 1e63f2c0e3a4241b96d9423f73d3c3c3 305 Gene3D G3DSA:3.90.180.10 152 305 2.3E-15 T 28-03-2018 CU254_RS14105 1e63f2c0e3a4241b96d9423f73d3c3c3 305 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 145 166 - T 28-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 CU254_RS14105 1e63f2c0e3a4241b96d9423f73d3c3c3 305 Gene3D G3DSA:3.90.180.10 1 151 5.4E-41 T 28-03-2018 CU254_RS14105 1e63f2c0e3a4241b96d9423f73d3c3c3 305 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 91 1.8E-6 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CU254_RS21525 462c7401f82bcc73649c479e287859a9 444 Pfam PF07690 Major Facilitator Superfamily 28 352 2.5E-36 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS21525 462c7401f82bcc73649c479e287859a9 444 Gene3D G3DSA:1.20.1250.20 233 439 4.5E-21 T 28-03-2018 CU254_RS21525 462c7401f82bcc73649c479e287859a9 444 SUPERFAMILY SSF103473 5 430 1.44E-71 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS21525 462c7401f82bcc73649c479e287859a9 444 Gene3D G3DSA:1.20.1250.20 8 207 1.1E-38 T 28-03-2018 CU254_RS25495 44ba1fd35342391199f9dc597ecd39fd 1508 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 986 992 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CU254_RS25495 44ba1fd35342391199f9dc597ecd39fd 1508 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 1219 1332 1.1E-26 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CU254_RS25495 44ba1fd35342391199f9dc597ecd39fd 1508 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 747 1005 1.3E-31 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CU254_RS25495 44ba1fd35342391199f9dc597ecd39fd 1508 SUPERFAMILY SSF81653 784 882 1.57E-23 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CU254_RS25495 44ba1fd35342391199f9dc597ecd39fd 1508 Gene3D G3DSA:3.40.1110.10 944 1148 3.4E-30 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CU254_RS25495 44ba1fd35342391199f9dc597ecd39fd 1508 Gene3D G3DSA:1.20.1110.10 1273 1496 3.5E-31 T 28-03-2018 CU254_RS25495 44ba1fd35342391199f9dc597ecd39fd 1508 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 1250 1269 1.4E-29 T 28-03-2018 CU254_RS25495 44ba1fd35342391199f9dc597ecd39fd 1508 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 1171 1181 1.4E-29 T 28-03-2018 CU254_RS25495 44ba1fd35342391199f9dc597ecd39fd 1508 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 824 838 1.4E-29 T 28-03-2018 CU254_RS25495 44ba1fd35342391199f9dc597ecd39fd 1508 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 1274 1286 1.4E-29 T 28-03-2018 CU254_RS25495 44ba1fd35342391199f9dc597ecd39fd 1508 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 1149 1160 1.4E-29 T 28-03-2018 CU254_RS25495 44ba1fd35342391199f9dc597ecd39fd 1508 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 984 998 1.4E-29 T 28-03-2018 CU254_RS25495 44ba1fd35342391199f9dc597ecd39fd 1508 Pfam PF00702 haloacid dehalogenase-like hydrolase 980 1264 9.4E-28 T 28-03-2018 CU254_RS25495 44ba1fd35342391199f9dc597ecd39fd 1508 SUPERFAMILY SSF81665 885 978 9.29E-52 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CU254_RS25495 44ba1fd35342391199f9dc597ecd39fd 1508 SUPERFAMILY SSF81665 656 775 9.29E-52 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CU254_RS25495 44ba1fd35342391199f9dc597ecd39fd 1508 SUPERFAMILY SSF81665 1300 1481 9.29E-52 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CU254_RS25495 44ba1fd35342391199f9dc597ecd39fd 1508 Gene3D G3DSA:3.40.50.1000 1149 1272 3.3E-17 T 28-03-2018 IPR023214 HAD-like domain CU254_RS25495 44ba1fd35342391199f9dc597ecd39fd 1508 Gene3D G3DSA:3.40.50.1000 355 589 0.17 T 28-03-2018 IPR023214 HAD-like domain CU254_RS25495 44ba1fd35342391199f9dc597ecd39fd 1508 Gene3D G3DSA:2.70.150.10 635 885 1.5E-29 T 28-03-2018 CU254_RS25495 44ba1fd35342391199f9dc597ecd39fd 1508 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 1222 1238 2.0E-12 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CU254_RS25495 44ba1fd35342391199f9dc597ecd39fd 1508 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 1282 1307 2.0E-12 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CU254_RS25495 44ba1fd35342391199f9dc597ecd39fd 1508 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 1107 1125 2.0E-12 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CU254_RS25495 44ba1fd35342391199f9dc597ecd39fd 1508 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 1250 1266 2.0E-12 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CU254_RS25495 44ba1fd35342391199f9dc597ecd39fd 1508 SUPERFAMILY SSF56784 982 1002 3.96E-42 T 28-03-2018 IPR023214 HAD-like domain CU254_RS25495 44ba1fd35342391199f9dc597ecd39fd 1508 SUPERFAMILY SSF56784 1104 1355 3.96E-42 T 28-03-2018 IPR023214 HAD-like domain CU254_RS25495 44ba1fd35342391199f9dc597ecd39fd 1508 Pfam PF00689 Cation transporting ATPase, C-terminus 1335 1494 8.5E-15 T 28-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 CU254_RS25495 44ba1fd35342391199f9dc597ecd39fd 1508 Pfam PF00122 E1-E2 ATPase 775 964 8.0E-43 T 28-03-2018 CU254_RS36750 02be8444b0138e343471675b610224eb 200 Gene3D G3DSA:3.40.30.10 36 200 1.2E-18 T 28-03-2018 CU254_RS36750 02be8444b0138e343471675b610224eb 200 SUPERFAMILY SSF52833 76 180 1.39E-19 T 28-03-2018 IPR012336 Thioredoxin-like fold CU254_RS36750 02be8444b0138e343471675b610224eb 200 Pfam PF08534 Redoxin 67 182 7.6E-9 T 28-03-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 CU254_RS07105 f97679ef04202e71f8ef28240ce44892 365 Pfam PF01820 D-ala D-ala ligase N-terminus 7 133 1.8E-29 T 28-03-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CU254_RS07105 f97679ef04202e71f8ef28240ce44892 365 PIRSF PIRSF039102 3 363 1.0E-104 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CU254_RS07105 f97679ef04202e71f8ef28240ce44892 365 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 111 122 - T 28-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CU254_RS07105 f97679ef04202e71f8ef28240ce44892 365 Gene3D G3DSA:3.30.1490.20 126 214 1.5E-24 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CU254_RS07105 f97679ef04202e71f8ef28240ce44892 365 SUPERFAMILY SSF56059 144 358 3.54E-53 T 28-03-2018 CU254_RS07105 f97679ef04202e71f8ef28240ce44892 365 Gene3D G3DSA:3.40.50.20 2 125 3.5E-39 T 28-03-2018 CU254_RS07105 f97679ef04202e71f8ef28240ce44892 365 Gene3D G3DSA:3.30.470.20 215 363 2.2E-40 T 28-03-2018 CU254_RS07105 f97679ef04202e71f8ef28240ce44892 365 SUPERFAMILY SSF52440 5 143 2.69E-34 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CU254_RS07105 f97679ef04202e71f8ef28240ce44892 365 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 7 357 1.1E-104 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CU254_RS07105 f97679ef04202e71f8ef28240ce44892 365 Pfam PF07478 D-ala D-ala ligase C-terminus 151 355 3.6E-67 T 28-03-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CU254_RS07105 f97679ef04202e71f8ef28240ce44892 365 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 300 328 - T 28-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CU254_RS07105 f97679ef04202e71f8ef28240ce44892 365 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 6 358 40.143 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CU254_RS29170 6e3e396b5ff40b10dfd5ab218719c029 372 Gene3D G3DSA:3.30.565.10 232 371 2.7E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS29170 6e3e396b5ff40b10dfd5ab218719c029 372 PIRSF PIRSF037434 1 372 2.0E-110 T 28-03-2018 IPR017205 Signal transduction histidine kinase, ChrS CU254_RS29170 6e3e396b5ff40b10dfd5ab218719c029 372 SUPERFAMILY SSF55874 245 367 3.8E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS29170 6e3e396b5ff40b10dfd5ab218719c029 372 PRINTS PR00344 Bacterial sensor protein C-terminal signature 353 366 4.0E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS29170 6e3e396b5ff40b10dfd5ab218719c029 372 PRINTS PR00344 Bacterial sensor protein C-terminal signature 310 324 4.0E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS29170 6e3e396b5ff40b10dfd5ab218719c029 372 PRINTS PR00344 Bacterial sensor protein C-terminal signature 329 347 4.0E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS29170 6e3e396b5ff40b10dfd5ab218719c029 372 SMART SM00387 274 369 5.0E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS29170 6e3e396b5ff40b10dfd5ab218719c029 372 Pfam PF07730 Histidine kinase 174 240 5.1E-15 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CU254_RS29170 6e3e396b5ff40b10dfd5ab218719c029 372 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 277 368 2.2E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS22040 be56885fe250cf04244a124b1bc68e1f 470 Gene3D G3DSA:3.40.309.10 263 454 1.6E-69 T 28-03-2018 CU254_RS22040 be56885fe250cf04244a124b1bc68e1f 470 Gene3D G3DSA:3.40.605.10 1 262 1.5E-91 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CU254_RS22040 be56885fe250cf04244a124b1bc68e1f 470 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 272 283 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CU254_RS22040 be56885fe250cf04244a124b1bc68e1f 470 Pfam PF00171 Aldehyde dehydrogenase family 13 468 3.7E-166 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CU254_RS22040 be56885fe250cf04244a124b1bc68e1f 470 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 244 251 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CU254_RS22040 be56885fe250cf04244a124b1bc68e1f 470 SUPERFAMILY SSF53720 7 468 9.29E-162 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CU254_RS12075 8b8b089a32ea854be2f477b57b5b19cd 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 2.7E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS12075 8b8b089a32ea854be2f477b57b5b19cd 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 2.7E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS12075 8b8b089a32ea854be2f477b57b5b19cd 201 Gene3D G3DSA:1.10.357.10 62 201 4.5E-19 T 28-03-2018 CU254_RS12075 8b8b089a32ea854be2f477b57b5b19cd 201 Gene3D G3DSA:1.10.10.60 10 61 2.1E-17 T 28-03-2018 CU254_RS12075 8b8b089a32ea854be2f477b57b5b19cd 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 66 4.5E-18 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS12075 8b8b089a32ea854be2f477b57b5b19cd 201 SUPERFAMILY SSF46689 13 91 3.94E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS12075 8b8b089a32ea854be2f477b57b5b19cd 201 SUPERFAMILY SSF48498 88 200 2.55E-17 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS08255 cb5ba6f2ba6d53255257eb95d95431d9 164 SUPERFAMILY SSF46785 23 152 3.76E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS08255 cb5ba6f2ba6d53255257eb95d95431d9 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 62 78 1.8E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS08255 cb5ba6f2ba6d53255257eb95d95431d9 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 130 150 1.8E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS08255 cb5ba6f2ba6d53255257eb95d95431d9 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 79 94 1.8E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS08255 cb5ba6f2ba6d53255257eb95d95431d9 164 Pfam PF01047 MarR family 49 105 1.1E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS08255 cb5ba6f2ba6d53255257eb95d95431d9 164 Gene3D G3DSA:1.10.10.10 3 162 8.4E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS08255 cb5ba6f2ba6d53255257eb95d95431d9 164 SMART SM00347 38 140 5.3E-15 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS15460 3358692eed2b8de3302d725298fe498e 650 TIGRFAM TIGR01342 acon_putative: putative aconitate hydratase 6 643 4.4E-230 T 28-03-2018 IPR006250 Aconitase, putative CU254_RS15460 3358692eed2b8de3302d725298fe498e 650 Pfam PF00694 Aconitase C-terminal domain 529 584 1.3E-20 T 28-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 CU254_RS15460 3358692eed2b8de3302d725298fe498e 650 SUPERFAMILY SSF53732 4 420 1.15E-127 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CU254_RS15460 3358692eed2b8de3302d725298fe498e 650 Gene3D G3DSA:3.40.1060.10 149 271 2.4E-30 T 28-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CU254_RS15460 3358692eed2b8de3302d725298fe498e 650 SUPERFAMILY SSF52016 453 647 8.63E-51 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CU254_RS15460 3358692eed2b8de3302d725298fe498e 650 Gene3D G3DSA:3.20.19.10 526 650 4.4E-34 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CU254_RS15460 3358692eed2b8de3302d725298fe498e 650 PRINTS PR00415 Aconitase family signature 112 125 1.1E-18 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CU254_RS15460 3358692eed2b8de3302d725298fe498e 650 PRINTS PR00415 Aconitase family signature 188 201 1.1E-18 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CU254_RS15460 3358692eed2b8de3302d725298fe498e 650 PRINTS PR00415 Aconitase family signature 351 364 1.1E-18 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CU254_RS15460 3358692eed2b8de3302d725298fe498e 650 PRINTS PR00415 Aconitase family signature 269 283 1.1E-18 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CU254_RS15460 3358692eed2b8de3302d725298fe498e 650 PRINTS PR00415 Aconitase family signature 126 141 1.1E-18 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CU254_RS15460 3358692eed2b8de3302d725298fe498e 650 Gene3D G3DSA:3.30.499.10 1 148 1.2E-37 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CU254_RS15460 3358692eed2b8de3302d725298fe498e 650 Pfam PF00330 Aconitase family (aconitate hydratase) 27 409 7.3E-85 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CU254_RS15460 3358692eed2b8de3302d725298fe498e 650 Gene3D G3DSA:3.20.19.10 466 525 4.4E-12 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CU254_RS15460 3358692eed2b8de3302d725298fe498e 650 Gene3D G3DSA:3.30.499.10 272 439 4.8E-42 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CU254_RS22530 979c6eca20011cc54a15c581fca5ed32 252 Gene3D G3DSA:3.30.450.40 65 245 1.1E-49 T 28-03-2018 IPR029016 GAF domain-like CU254_RS22530 979c6eca20011cc54a15c581fca5ed32 252 Gene3D G3DSA:1.10.10.10 1 60 3.8E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS22530 979c6eca20011cc54a15c581fca5ed32 252 SMART SM00346 2 89 3.5E-17 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS22530 979c6eca20011cc54a15c581fca5ed32 252 Pfam PF01614 Bacterial transcriptional regulator 117 240 1.3E-32 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal CU254_RS22530 979c6eca20011cc54a15c581fca5ed32 252 Pfam PF09339 IclR helix-turn-helix domain 4 53 6.7E-11 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS22530 979c6eca20011cc54a15c581fca5ed32 252 SUPERFAMILY SSF46785 3 72 2.09E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS22530 979c6eca20011cc54a15c581fca5ed32 252 SUPERFAMILY SSF55781 57 245 5.76E-49 T 28-03-2018 IPR029016 GAF domain-like CU254_RS36310 078a6533d2165b13fa02447f9a250f7c 164 Gene3D G3DSA:3.30.70.560 1 160 4.6E-48 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CU254_RS36310 078a6533d2165b13fa02447f9a250f7c 164 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 5 130 9.6E-28 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CU254_RS36310 078a6533d2165b13fa02447f9a250f7c 164 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 4 130 2.2E-33 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CU254_RS36310 078a6533d2165b13fa02447f9a250f7c 164 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 85 96 - T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CU254_RS36310 078a6533d2165b13fa02447f9a250f7c 164 SUPERFAMILY SSF55083 3 144 1.31E-40 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CU254_RS04465 819da1d748c926eedbf6030282179b88 429 Gene3D G3DSA:1.20.1250.20 226 429 1.9E-21 T 28-03-2018 CU254_RS04465 819da1d748c926eedbf6030282179b88 429 Pfam PF07690 Major Facilitator Superfamily 21 355 3.8E-31 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS04465 819da1d748c926eedbf6030282179b88 429 Gene3D G3DSA:1.20.1250.20 2 199 5.0E-24 T 28-03-2018 CU254_RS04465 819da1d748c926eedbf6030282179b88 429 SUPERFAMILY SSF103473 7 419 1.05E-59 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS20170 a94cea1410996d182c7728a82005f9e5 328 SUPERFAMILY SSF50129 1 174 1.46E-39 T 28-03-2018 IPR011032 GroES-like CU254_RS20170 a94cea1410996d182c7728a82005f9e5 328 Gene3D G3DSA:3.40.50.720 163 272 1.1E-15 T 28-03-2018 CU254_RS20170 a94cea1410996d182c7728a82005f9e5 328 Gene3D G3DSA:3.90.180.10 1 162 5.9E-37 T 28-03-2018 CU254_RS20170 a94cea1410996d182c7728a82005f9e5 328 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 137 2.4E-25 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CU254_RS20170 a94cea1410996d182c7728a82005f9e5 328 SUPERFAMILY SSF51735 145 296 2.25E-20 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS20170 a94cea1410996d182c7728a82005f9e5 328 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 63 77 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CU254_RS02700 0e63ea10fa75082611552b76d14bba09 253 Gene3D G3DSA:1.10.10.60 163 210 1.8E-11 T 28-03-2018 CU254_RS02700 0e63ea10fa75082611552b76d14bba09 253 SUPERFAMILY SSF51215 20 132 8.11E-12 T 28-03-2018 CU254_RS02700 0e63ea10fa75082611552b76d14bba09 253 Gene3D G3DSA:1.10.10.60 211 253 1.4E-12 T 28-03-2018 CU254_RS02700 0e63ea10fa75082611552b76d14bba09 253 SUPERFAMILY SSF46689 205 252 4.93E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS02700 0e63ea10fa75082611552b76d14bba09 253 Pfam PF02311 AraC-like ligand binding domain 16 133 2.8E-16 T 28-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CU254_RS02700 0e63ea10fa75082611552b76d14bba09 253 Gene3D G3DSA:2.60.120.280 8 162 7.4E-8 T 28-03-2018 CU254_RS02700 0e63ea10fa75082611552b76d14bba09 253 SUPERFAMILY SSF46689 156 202 2.69E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS02700 0e63ea10fa75082611552b76d14bba09 253 Pfam PF12833 Helix-turn-helix domain 177 252 8.8E-20 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS02700 0e63ea10fa75082611552b76d14bba09 253 SMART SM00342 169 251 2.0E-20 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS08075 8786a2277652510f8aa0be906967c8e2 274 Gene3D G3DSA:3.40.50.150 22 248 1.4E-25 T 28-03-2018 CU254_RS08075 8786a2277652510f8aa0be906967c8e2 274 Pfam PF08241 Methyltransferase domain 56 150 7.3E-17 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CU254_RS08075 8786a2277652510f8aa0be906967c8e2 274 SUPERFAMILY SSF53335 27 232 7.02E-30 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS30965 46c9afc1f490f533f7715086b6821174 224 Pfam PF01694 Rhomboid family 73 205 1.1E-24 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CU254_RS30965 46c9afc1f490f533f7715086b6821174 224 SUPERFAMILY SSF144091 33 208 2.62E-28 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CU254_RS30965 46c9afc1f490f533f7715086b6821174 224 Gene3D G3DSA:1.20.1540.10 30 206 9.3E-22 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CU254_RS07670 bdbb7f42c079cb73444fb161f82d551f 336 SUPERFAMILY SSF53822 64 330 1.68E-66 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CU254_RS07670 bdbb7f42c079cb73444fb161f82d551f 336 Gene3D G3DSA:3.40.50.2300 59 174 7.7E-32 T 28-03-2018 CU254_RS07670 bdbb7f42c079cb73444fb161f82d551f 336 Pfam PF13377 Periplasmic binding protein-like domain 169 327 6.6E-41 T 28-03-2018 CU254_RS07670 bdbb7f42c079cb73444fb161f82d551f 336 Gene3D G3DSA:3.40.50.2300 175 330 7.2E-45 T 28-03-2018 CU254_RS07670 bdbb7f42c079cb73444fb161f82d551f 336 Gene3D G3DSA:1.10.260.40 5 58 1.4E-18 T 28-03-2018 CU254_RS07670 bdbb7f42c079cb73444fb161f82d551f 336 SUPERFAMILY SSF47413 2 61 2.36E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS07670 bdbb7f42c079cb73444fb161f82d551f 336 SMART SM00354 3 73 4.4E-19 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CU254_RS07670 bdbb7f42c079cb73444fb161f82d551f 336 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 49 3.2E-14 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CU254_RS38655 120ab5b5c0cef6719acf5e5c6a3210d5 252 Gene3D G3DSA:1.10.1660.10 3 139 4.9E-34 T 28-03-2018 CU254_RS38655 120ab5b5c0cef6719acf5e5c6a3210d5 252 SMART SM00422 6 75 6.5E-16 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS38655 120ab5b5c0cef6719acf5e5c6a3210d5 252 Pfam PF13411 MerR HTH family regulatory protein 7 74 1.1E-16 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS38655 120ab5b5c0cef6719acf5e5c6a3210d5 252 Gene3D G3DSA:1.10.490.50 159 249 1.3E-24 T 28-03-2018 CU254_RS38655 120ab5b5c0cef6719acf5e5c6a3210d5 252 Pfam PF07739 TipAS antibiotic-recognition domain 130 245 9.5E-33 T 28-03-2018 IPR012925 TipAS antibiotic-recognition domain CU254_RS38655 120ab5b5c0cef6719acf5e5c6a3210d5 252 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 7 18 3.2E-5 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS38655 120ab5b5c0cef6719acf5e5c6a3210d5 252 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 18 31 3.2E-5 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS38655 120ab5b5c0cef6719acf5e5c6a3210d5 252 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 42 62 3.2E-5 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS38655 120ab5b5c0cef6719acf5e5c6a3210d5 252 SUPERFAMILY SSF46955 6 112 6.23E-26 T 28-03-2018 IPR009061 Putative DNA-binding domain CU254_RS38655 120ab5b5c0cef6719acf5e5c6a3210d5 252 SUPERFAMILY SSF89082 160 249 3.01E-21 T 28-03-2018 IPR012925 TipAS antibiotic-recognition domain CU254_RS35000 d05ee7a2471cee8e80deb3db0472e272 421 SUPERFAMILY SSF55874 298 420 8.38E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS35000 d05ee7a2471cee8e80deb3db0472e272 421 PIRSF PIRSF037434 26 421 1.9E-77 T 28-03-2018 IPR017205 Signal transduction histidine kinase, ChrS CU254_RS35000 d05ee7a2471cee8e80deb3db0472e272 421 SMART SM00387 331 421 1.4E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS35000 d05ee7a2471cee8e80deb3db0472e272 421 Gene3D G3DSA:3.30.565.10 188 421 7.9E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS35000 d05ee7a2471cee8e80deb3db0472e272 421 Pfam PF07730 Histidine kinase 226 293 1.9E-15 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CU254_RS35000 d05ee7a2471cee8e80deb3db0472e272 421 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 335 420 4.1E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS35000 d05ee7a2471cee8e80deb3db0472e272 421 PRINTS PR00344 Bacterial sensor protein C-terminal signature 367 381 1.8E-5 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS35000 d05ee7a2471cee8e80deb3db0472e272 421 PRINTS PR00344 Bacterial sensor protein C-terminal signature 383 401 1.8E-5 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS35000 d05ee7a2471cee8e80deb3db0472e272 421 PRINTS PR00344 Bacterial sensor protein C-terminal signature 407 420 1.8E-5 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS30960 7d7c7a6be84df1c5567ccfb4f0ae1136 266 Hamap MF_00258 Glutamate racemase [murI]. 6 257 36.163 T 28-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CU254_RS30960 7d7c7a6be84df1c5567ccfb4f0ae1136 266 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 181 191 - T 28-03-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CU254_RS30960 7d7c7a6be84df1c5567ccfb4f0ae1136 266 Gene3D G3DSA:3.40.50.1860 120 265 3.3E-46 T 28-03-2018 CU254_RS30960 7d7c7a6be84df1c5567ccfb4f0ae1136 266 Gene3D G3DSA:3.40.50.1860 4 119 1.8E-26 T 28-03-2018 CU254_RS30960 7d7c7a6be84df1c5567ccfb4f0ae1136 266 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 72 80 - T 28-03-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CU254_RS30960 7d7c7a6be84df1c5567ccfb4f0ae1136 266 Pfam PF01177 Asp/Glu/Hydantoin racemase 8 215 1.3E-32 T 28-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CU254_RS30960 7d7c7a6be84df1c5567ccfb4f0ae1136 266 SUPERFAMILY SSF53681 7 109 7.85E-32 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CU254_RS30960 7d7c7a6be84df1c5567ccfb4f0ae1136 266 TIGRFAM TIGR00067 glut_race: glutamate racemase 8 254 1.8E-67 T 28-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CU254_RS30960 7d7c7a6be84df1c5567ccfb4f0ae1136 266 SUPERFAMILY SSF53681 111 257 9.81E-39 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CU254_RS38285 e41b73c58ad1b39803c39e632cd106d0 367 Pfam PF00042 Globin 3 95 5.7E-13 T 28-03-2018 IPR000971 Globin GO:0020037 CU254_RS38285 e41b73c58ad1b39803c39e632cd106d0 367 Gene3D G3DSA:1.10.490.10 1 132 5.4E-34 T 28-03-2018 CU254_RS38285 e41b73c58ad1b39803c39e632cd106d0 367 SUPERFAMILY SSF46458 3 128 1.05E-34 T 28-03-2018 IPR009050 Globin-like CU254_RS38285 e41b73c58ad1b39803c39e632cd106d0 367 Pfam PF00970 Oxidoreductase FAD-binding domain 140 232 1.3E-12 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CU254_RS38285 e41b73c58ad1b39803c39e632cd106d0 367 Gene3D G3DSA:3.40.50.80 231 364 1.1E-19 T 28-03-2018 CU254_RS38285 e41b73c58ad1b39803c39e632cd106d0 367 SUPERFAMILY SSF63380 138 232 1.0E-22 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CU254_RS38285 e41b73c58ad1b39803c39e632cd106d0 367 Gene3D G3DSA:2.40.30.10 133 230 5.9E-18 T 28-03-2018 CU254_RS38285 e41b73c58ad1b39803c39e632cd106d0 367 Pfam PF00175 Oxidoreductase NAD-binding domain 244 345 4.0E-15 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CU254_RS38285 e41b73c58ad1b39803c39e632cd106d0 367 PRINTS PR00410 Phenol hydroxylase reductase family signature 243 262 2.3E-8 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CU254_RS38285 e41b73c58ad1b39803c39e632cd106d0 367 PRINTS PR00410 Phenol hydroxylase reductase family signature 165 177 2.3E-8 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CU254_RS38285 e41b73c58ad1b39803c39e632cd106d0 367 SUPERFAMILY SSF52343 237 365 3.54E-27 T 28-03-2018 CU254_RS41200 73e5cd5e7fa41c009f01f3f1adacef5a 892 Gene3D G3DSA:3.30.2430.10 33 176 5.0E-28 T 28-03-2018 CU254_RS41200 73e5cd5e7fa41c009f01f3f1adacef5a 892 SMART SM01260 538 858 2.7E-6 T 28-03-2018 IPR007822 Lanthionine synthetase C-like CU254_RS41200 73e5cd5e7fa41c009f01f3f1adacef5a 892 Gene3D G3DSA:3.30.200.20 218 302 7.4E-7 T 28-03-2018 CU254_RS41200 73e5cd5e7fa41c009f01f3f1adacef5a 892 SUPERFAMILY SSF56112 230 434 2.29E-28 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS41200 73e5cd5e7fa41c009f01f3f1adacef5a 892 SUPERFAMILY SSF158745 532 857 1.31E-24 T 28-03-2018 CU254_RS41200 73e5cd5e7fa41c009f01f3f1adacef5a 892 SMART SM00220 230 488 5.5E-6 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CU254_RS41200 73e5cd5e7fa41c009f01f3f1adacef5a 892 Pfam PF00069 Protein kinase domain 241 426 2.5E-13 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CU254_RS41200 73e5cd5e7fa41c009f01f3f1adacef5a 892 Gene3D G3DSA:1.50.10.20 573 792 5.5E-10 T 28-03-2018 CU254_RS41200 73e5cd5e7fa41c009f01f3f1adacef5a 892 PRINTS PR01955 Frankia sp. LanC-like protein signature 542 558 1.2E-5 T 28-03-2018 CU254_RS41200 73e5cd5e7fa41c009f01f3f1adacef5a 892 PRINTS PR01955 Frankia sp. LanC-like protein signature 831 848 1.2E-5 T 28-03-2018 CU254_RS41200 73e5cd5e7fa41c009f01f3f1adacef5a 892 PRINTS PR01955 Frankia sp. LanC-like protein signature 775 795 1.2E-5 T 28-03-2018 CU254_RS41200 73e5cd5e7fa41c009f01f3f1adacef5a 892 Gene3D G3DSA:1.10.510.10 303 572 2.9E-18 T 28-03-2018 CU254_RS24235 d07776b2f71aadec8120ec9528061210 395 Gene3D G3DSA:3.50.50.60 4 350 2.0E-37 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS24235 d07776b2f71aadec8120ec9528061210 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 284 299 3.2E-11 T 28-03-2018 CU254_RS24235 d07776b2f71aadec8120ec9528061210 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 148 163 3.2E-11 T 28-03-2018 CU254_RS24235 d07776b2f71aadec8120ec9528061210 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 3.2E-11 T 28-03-2018 CU254_RS24235 d07776b2f71aadec8120ec9528061210 395 SUPERFAMILY SSF51905 271 374 9.98E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS24235 d07776b2f71aadec8120ec9528061210 395 SUPERFAMILY SSF51905 4 169 9.98E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS24235 d07776b2f71aadec8120ec9528061210 395 Pfam PF01494 FAD binding domain 4 164 1.4E-9 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CU254_RS24235 d07776b2f71aadec8120ec9528061210 395 Pfam PF01494 FAD binding domain 282 324 5.1E-7 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CU254_RS32890 a5de12ca3fa0d33321cbb430c41285f6 631 Gene3D G3DSA:1.20.140.10 248 451 1.5E-43 T 28-03-2018 CU254_RS32890 a5de12ca3fa0d33321cbb430c41285f6 631 Gene3D G3DSA:1.20.140.10 491 618 5.9E-31 T 28-03-2018 CU254_RS32890 a5de12ca3fa0d33321cbb430c41285f6 631 SUPERFAMILY SSF47203 276 457 1.4E-46 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS32890 a5de12ca3fa0d33321cbb430c41285f6 631 SUPERFAMILY SSF47203 487 627 2.93E-33 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS32890 a5de12ca3fa0d33321cbb430c41285f6 631 Pfam PF01756 Acyl-CoA oxidase 502 627 1.2E-17 T 28-03-2018 IPR002655 Acyl-CoA oxidase, C-terminal GO:0003997|GO:0005777|GO:0006635 KEGG: 00071+1.3.3.6|KEGG: 00592+1.3.3.6|MetaCyc: PWY-5136|MetaCyc: PWY-6837|MetaCyc: PWY-6920|MetaCyc: PWY-7007|MetaCyc: PWY-7288|MetaCyc: PWY-7291|MetaCyc: PWY-7337|MetaCyc: PWY-7338|MetaCyc: PWY-7340|MetaCyc: PWY-735|MetaCyc: PWY-7574|MetaCyc: PWY-7606|MetaCyc: PWY-7726|MetaCyc: PWY-7854|MetaCyc: PWY-7858 CU254_RS32890 a5de12ca3fa0d33321cbb430c41285f6 631 PIRSF PIRSF000168 3 630 4.5E-166 T 28-03-2018 IPR012258 Acyl-CoA oxidase GO:0003997|GO:0005777|GO:0006631|GO:0071949 KEGG: 00071+1.3.3.6|KEGG: 00592+1.3.3.6|MetaCyc: PWY-5136|MetaCyc: PWY-6837|MetaCyc: PWY-6920|MetaCyc: PWY-7007|MetaCyc: PWY-7288|MetaCyc: PWY-7291|MetaCyc: PWY-7337|MetaCyc: PWY-7338|MetaCyc: PWY-7340|MetaCyc: PWY-735|MetaCyc: PWY-7574|MetaCyc: PWY-7606|MetaCyc: PWY-7726|MetaCyc: PWY-7854|MetaCyc: PWY-7858 CU254_RS32890 a5de12ca3fa0d33321cbb430c41285f6 631 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 137 246 3.7E-16 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CU254_RS32890 a5de12ca3fa0d33321cbb430c41285f6 631 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 280 437 5.1E-13 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS32890 a5de12ca3fa0d33321cbb430c41285f6 631 SUPERFAMILY SSF56645 22 259 1.57E-52 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS32890 a5de12ca3fa0d33321cbb430c41285f6 631 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 49 131 4.7E-5 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS32890 a5de12ca3fa0d33321cbb430c41285f6 631 Gene3D G3DSA:1.10.540.10 11 135 7.3E-22 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS32890 a5de12ca3fa0d33321cbb430c41285f6 631 Gene3D G3DSA:2.40.110.10 136 247 4.4E-27 T 28-03-2018 CU254_RS18775 87a414c62d505acd6a0b02bf098ef857 397 SUPERFAMILY SSF55781 20 158 2.18E-26 T 28-03-2018 IPR029016 GAF domain-like CU254_RS18775 87a414c62d505acd6a0b02bf098ef857 397 SUPERFAMILY SSF81606 184 392 2.75E-9 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CU254_RS18775 87a414c62d505acd6a0b02bf098ef857 397 Gene3D G3DSA:3.30.450.40 20 160 1.4E-27 T 28-03-2018 IPR029016 GAF domain-like CU254_RS18775 87a414c62d505acd6a0b02bf098ef857 397 SMART SM00065 19 164 8.8E-18 T 28-03-2018 IPR003018 GAF domain GO:0005515 CU254_RS18775 87a414c62d505acd6a0b02bf098ef857 397 Pfam PF13185 GAF domain 20 155 5.2E-19 T 28-03-2018 IPR003018 GAF domain GO:0005515 CU254_RS18775 87a414c62d505acd6a0b02bf098ef857 397 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 209 393 1.1E-43 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CU254_RS18775 87a414c62d505acd6a0b02bf098ef857 397 Gene3D G3DSA:3.60.40.10 161 396 2.5E-39 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CU254_RS18775 87a414c62d505acd6a0b02bf098ef857 397 SMART SM00331 181 393 2.3E-36 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CU254_RS35705 e68836fc9ebe69c83d718f7ab4924ec1 156 Pfam PF07617 Protein of unknown function (DUF1579) 7 80 7.6E-8 T 28-03-2018 IPR011473 Protein of unknown function DUF1579 CU254_RS18830 4bf22cd917eba53466e9a59416ad1047 330 Gene3D G3DSA:3.10.450.50 11 150 8.8E-10 T 28-03-2018 CU254_RS18830 4bf22cd917eba53466e9a59416ad1047 330 Gene3D G3DSA:3.10.450.50 166 320 1.4E-18 T 28-03-2018 CU254_RS18830 4bf22cd917eba53466e9a59416ad1047 330 Pfam PF07366 SnoaL-like polyketide cyclase 187 317 2.2E-16 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CU254_RS18830 4bf22cd917eba53466e9a59416ad1047 330 SUPERFAMILY SSF54427 11 151 1.67E-15 T 28-03-2018 IPR032710 NTF2-like domain CU254_RS18830 4bf22cd917eba53466e9a59416ad1047 330 SUPERFAMILY SSF54427 186 317 4.66E-24 T 28-03-2018 IPR032710 NTF2-like domain CU254_RS19580 e2453db94139bc4ba500aebb1a626ab8 329 SUPERFAMILY SSF51735 3 156 2.93E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS19580 e2453db94139bc4ba500aebb1a626ab8 329 Gene3D G3DSA:3.90.110.10 157 325 2.0E-54 T 28-03-2018 CU254_RS19580 e2453db94139bc4ba500aebb1a626ab8 329 TIGRFAM TIGR01759 MalateDH-SF1: malate dehydrogenase 4 323 2.1E-144 T 28-03-2018 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 CU254_RS19580 e2453db94139bc4ba500aebb1a626ab8 329 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 157 323 9.5E-34 T 28-03-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 CU254_RS19580 e2453db94139bc4ba500aebb1a626ab8 329 ProSitePatterns PS00068 Malate dehydrogenase active site signature. 156 168 - T 28-03-2018 IPR001252 Malate dehydrogenase, active site GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383|Reactome: R-HSA-70263 CU254_RS19580 e2453db94139bc4ba500aebb1a626ab8 329 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 7 148 3.1E-30 T 28-03-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 CU254_RS19580 e2453db94139bc4ba500aebb1a626ab8 329 PIRSF PIRSF000102 2 328 3.1E-60 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CU254_RS19580 e2453db94139bc4ba500aebb1a626ab8 329 SUPERFAMILY SSF56327 157 325 5.25E-60 T 28-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CU254_RS19580 e2453db94139bc4ba500aebb1a626ab8 329 Gene3D G3DSA:3.40.50.720 7 156 3.0E-24 T 28-03-2018 CU254_RS19580 e2453db94139bc4ba500aebb1a626ab8 329 Hamap MF_01517 Malate dehydrogenase [mdh]. 2 327 56.531 T 28-03-2018 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 CU254_RS31975 831b5a44734565bd7f98f26a8a609203 244 PIRSF PIRSF015736 9 244 2.6E-56 T 28-03-2018 IPR026286 Maleate isomerase/Arylmalonate decarboxylase CU254_RS31975 831b5a44734565bd7f98f26a8a609203 244 Gene3D G3DSA:3.40.50.1860 20 118 3.0E-4 T 28-03-2018 CU254_RS31975 831b5a44734565bd7f98f26a8a609203 244 Pfam PF01177 Asp/Glu/Hydantoin racemase 60 222 8.3E-8 T 28-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CU254_RS31975 831b5a44734565bd7f98f26a8a609203 244 Gene3D G3DSA:3.40.50.1860 119 214 0.093 T 28-03-2018 CU254_RS24230 79ceec258db4a5f10b82b4d4d20e6721 610 Pfam PF13515 Fusaric acid resistance protein-like 348 456 2.4E-6 T 28-03-2018 CU254_RS12660 418ad540355c8401703cf5bc4ce8bc0a 870 Gene3D G3DSA:3.20.20.80 132 463 4.5E-97 T 28-03-2018 CU254_RS12660 418ad540355c8401703cf5bc4ce8bc0a 870 Gene3D G3DSA:3.30.379.10 21 131 1.6E-28 T 28-03-2018 CU254_RS12660 418ad540355c8401703cf5bc4ce8bc0a 870 Pfam PF00652 Ricin-type beta-trefoil lectin domain 746 866 1.1E-28 T 28-03-2018 IPR000772 Ricin B, lectin domain CU254_RS12660 418ad540355c8401703cf5bc4ce8bc0a 870 SMART SM00458 745 869 1.8E-32 T 28-03-2018 IPR000772 Ricin B, lectin domain CU254_RS12660 418ad540355c8401703cf5bc4ce8bc0a 870 Gene3D G3DSA:1.20.120.670 464 737 2.3E-85 T 28-03-2018 CU254_RS12660 418ad540355c8401703cf5bc4ce8bc0a 870 Gene3D G3DSA:2.80.10.50 793 827 3.6E-13 T 28-03-2018 CU254_RS12660 418ad540355c8401703cf5bc4ce8bc0a 870 SUPERFAMILY SSF50370 747 867 2.78E-41 T 28-03-2018 IPR000772 Ricin B, lectin domain CU254_RS12660 418ad540355c8401703cf5bc4ce8bc0a 870 Pfam PF05089 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain 136 462 1.3E-92 T 28-03-2018 IPR024733 Alpha-N-acetylglucosaminidase, tim-barrel domain KEGG: 00531+3.2.1.50|Reactome: R-HSA-2024096 CU254_RS12660 418ad540355c8401703cf5bc4ce8bc0a 870 Pfam PF12971 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain 41 122 8.6E-21 T 28-03-2018 IPR024240 Alpha-N-acetylglucosaminidase, N-terminal KEGG: 00531+3.2.1.50|Reactome: R-HSA-2024096 CU254_RS12660 418ad540355c8401703cf5bc4ce8bc0a 870 Gene3D G3DSA:4.10.1090.10 738 792 1.5E-14 T 28-03-2018 CU254_RS12660 418ad540355c8401703cf5bc4ce8bc0a 870 Pfam PF12972 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain 470 734 1.0E-78 T 28-03-2018 IPR024732 Alpha-N-acetylglucosaminidase, C-terminal KEGG: 00531+3.2.1.50|Reactome: R-HSA-2024096 CU254_RS12660 418ad540355c8401703cf5bc4ce8bc0a 870 Gene3D G3DSA:2.80.10.50 828 870 5.1E-12 T 28-03-2018 CU254_RS01650 3450ed4178ff3f8f968b518557c45d9d 293 Pfam PF00483 Nucleotidyl transferase 2 237 1.2E-62 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CU254_RS01650 3450ed4178ff3f8f968b518557c45d9d 293 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 2 286 1.9E-137 T 28-03-2018 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|KEGG: 00525+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 CU254_RS01650 3450ed4178ff3f8f968b518557c45d9d 293 SUPERFAMILY SSF53448 2 285 1.01E-81 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS01650 3450ed4178ff3f8f968b518557c45d9d 293 Gene3D G3DSA:3.90.550.10 1 289 3.9E-64 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS25880 12da4feed31cb13dcc9faa4d2cd1fdad 222 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 52 194 5.9E-6 T 28-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal CU254_RS38595 f2373b19a627fde0cee8cfa278734656 201 Pfam PF00005 ABC transporter 27 155 4.9E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS38595 f2373b19a627fde0cee8cfa278734656 201 Gene3D G3DSA:3.40.50.300 7 201 7.9E-41 T 28-03-2018 CU254_RS38595 f2373b19a627fde0cee8cfa278734656 201 SMART SM00382 34 201 2.2E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS38595 f2373b19a627fde0cee8cfa278734656 201 SUPERFAMILY SSF52540 9 201 4.46E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS30755 825cd691ff875571d92511c09a212f94 836 Pfam PF08376 Nitrate and nitrite sensing 69 290 6.3E-25 T 28-03-2018 IPR013587 Nitrate/nitrite sensing protein CU254_RS30755 825cd691ff875571d92511c09a212f94 836 SMART SM00387 520 633 9.2E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS30755 825cd691ff875571d92511c09a212f94 836 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 523 629 1.1E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS30755 825cd691ff875571d92511c09a212f94 836 Gene3D G3DSA:3.30.565.10 488 641 4.1E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS30755 825cd691ff875571d92511c09a212f94 836 SUPERFAMILY SSF55874 512 630 1.7E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS33280 5d1d69824a1e6bba711eb70820b0623a 491 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 375 457 8.1E-16 T 28-03-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain CU254_RS33280 5d1d69824a1e6bba711eb70820b0623a 491 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 96 264 1.3E-42 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CU254_RS33280 5d1d69824a1e6bba711eb70820b0623a 491 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 96 264 4.0E-34 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CU254_RS13875 08868d9c9744db6cb11c8c286d060f1b 172 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 32 169 5.4E-17 T 28-03-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal CU254_RS13875 08868d9c9744db6cb11c8c286d060f1b 172 SUPERFAMILY SSF81296 32 171 2.52E-35 T 28-03-2018 IPR014756 Immunoglobulin E-set CU254_RS13875 08868d9c9744db6cb11c8c286d060f1b 172 Gene3D G3DSA:2.70.50.50 32 172 1.7E-33 T 28-03-2018 CU254_RS32485 0e9928f04cd67d465d4a8dcbec61c18f 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 1.2E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS32485 0e9928f04cd67d465d4a8dcbec61c18f 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 1.2E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS32485 0e9928f04cd67d465d4a8dcbec61c18f 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 55 4.1E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS32485 0e9928f04cd67d465d4a8dcbec61c18f 190 SUPERFAMILY SSF46689 6 73 2.5E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS32485 0e9928f04cd67d465d4a8dcbec61c18f 190 Gene3D G3DSA:1.10.10.60 7 60 4.5E-18 T 28-03-2018 CU254_RS32485 0e9928f04cd67d465d4a8dcbec61c18f 190 Gene3D G3DSA:1.10.357.10 61 188 3.3E-19 T 28-03-2018 CU254_RS32485 0e9928f04cd67d465d4a8dcbec61c18f 190 ProSitePatterns PS01081 TetR-type HTH domain signature. 24 55 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CU254_RS39595 51591692c57cdefd35e31cd009943ddc 198 SUPERFAMILY SSF63817 56 197 6.8E-15 T 28-03-2018 IPR023365 Sortase domain CU254_RS39595 51591692c57cdefd35e31cd009943ddc 198 Pfam PF04203 Sortase family 57 197 1.4E-17 T 28-03-2018 IPR005754 Sortase family CU254_RS39595 51591692c57cdefd35e31cd009943ddc 198 Gene3D G3DSA:2.40.260.10 40 198 4.9E-24 T 28-03-2018 IPR023365 Sortase domain CU254_RS27230 b2016c44846bffab42ca6c0751184487 530 Pfam PF13699 Domain of unknown function (DUF4157) 34 109 8.7E-28 T 28-03-2018 IPR025295 Domain of unknown function DUF4157 CU254_RS09740 72ca800caef22b1b66b4d8ea4cedbca7 481 Hamap MF_00900 GTPase HflX [hflX]. 75 448 47.37 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 CU254_RS09740 72ca800caef22b1b66b4d8ea4cedbca7 481 SUPERFAMILY SSF52540 255 444 7.62E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS09740 72ca800caef22b1b66b4d8ea4cedbca7 481 Pfam PF16360 GTP-binding GTPase Middle Region 162 248 1.4E-28 T 28-03-2018 IPR032305 GTP-binding protein, middle domain CU254_RS09740 72ca800caef22b1b66b4d8ea4cedbca7 481 PIRSF PIRSF006809 19 53 280.0 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 CU254_RS09740 72ca800caef22b1b66b4d8ea4cedbca7 481 PIRSF PIRSF006809 47 480 5.8E-158 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 CU254_RS09740 72ca800caef22b1b66b4d8ea4cedbca7 481 Pfam PF13167 GTP-binding GTPase N-terminal 72 160 4.7E-34 T 28-03-2018 IPR025121 GTPase HflX, N-terminal CU254_RS09740 72ca800caef22b1b66b4d8ea4cedbca7 481 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 256 276 8.3E-8 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CU254_RS09740 72ca800caef22b1b66b4d8ea4cedbca7 481 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 323 341 8.3E-8 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CU254_RS09740 72ca800caef22b1b66b4d8ea4cedbca7 481 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 56 419 7.2E-134 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 CU254_RS09740 72ca800caef22b1b66b4d8ea4cedbca7 481 Gene3D G3DSA:1.20.120.430 316 464 3.8E-13 T 28-03-2018 CU254_RS09740 72ca800caef22b1b66b4d8ea4cedbca7 481 Pfam PF01926 50S ribosome-binding GTPase 256 378 7.9E-22 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CU254_RS09740 72ca800caef22b1b66b4d8ea4cedbca7 481 Gene3D G3DSA:3.40.50.300 68 315 3.2E-16 T 28-03-2018 CU254_RS35115 c738c2bb5294fdf5099f96549abd4010 257 Gene3D G3DSA:2.140.10.10 41 254 1.1E-7 T 28-03-2018 CU254_RS35115 c738c2bb5294fdf5099f96549abd4010 257 Pfam PF05096 Glutamine cyclotransferase 11 248 1.8E-83 T 28-03-2018 IPR007788 Glutaminyl-peptide cyclotransferase GO:0016603|GO:0017186 CU254_RS35115 c738c2bb5294fdf5099f96549abd4010 257 SUPERFAMILY SSF50969 44 239 1.22E-12 T 28-03-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like CU254_RS08915 0b9cc3e402ab3839beb5f401d02cd0f8 150 Gene3D G3DSA:3.40.630.30 36 142 2.4E-14 T 28-03-2018 CU254_RS08915 0b9cc3e402ab3839beb5f401d02cd0f8 150 SUPERFAMILY SSF55729 4 141 3.01E-19 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS08915 0b9cc3e402ab3839beb5f401d02cd0f8 150 Gene3D G3DSA:1.10.287.900 3 35 2.9E-14 T 28-03-2018 IPR027455 Spermine/spermidine acetyltransferase, N-terminal domain KEGG: 00330+2.3.1.57|MetaCyc: PWY-0|MetaCyc: PWY-6117 CU254_RS08915 0b9cc3e402ab3839beb5f401d02cd0f8 150 Pfam PF00583 Acetyltransferase (GNAT) family 52 133 2.4E-9 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS28835 e69050c94840ad90330fba0358206fea 557 Gene3D G3DSA:3.40.190.10 215 311 3.4E-24 T 28-03-2018 CU254_RS28835 e69050c94840ad90330fba0358206fea 557 Gene3D G3DSA:3.10.105.10 312 527 2.1E-43 T 28-03-2018 CU254_RS28835 e69050c94840ad90330fba0358206fea 557 SUPERFAMILY SSF53850 52 555 1.27E-80 T 28-03-2018 CU254_RS28835 e69050c94840ad90330fba0358206fea 557 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 117 474 3.4E-54 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CU254_RS28835 e69050c94840ad90330fba0358206fea 557 Gene3D G3DSA:3.90.76.10 66 214 4.7E-11 T 28-03-2018 CU254_RS28835 e69050c94840ad90330fba0358206fea 557 PIRSF PIRSF002741 12 540 3.9E-44 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CU254_RS10180 5936f4ffbd39529e0e94629ac7bafad6 1004 Gene3D G3DSA:3.40.50.300 13 266 1.9E-10 T 28-03-2018 CU254_RS10180 5936f4ffbd39529e0e94629ac7bafad6 1004 SMART SM00421 937 994 2.0E-24 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS10180 5936f4ffbd39529e0e94629ac7bafad6 1004 Pfam PF00196 Bacterial regulatory proteins, luxR family 939 994 8.6E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS10180 5936f4ffbd39529e0e94629ac7bafad6 1004 SUPERFAMILY SSF46894 930 1001 2.14E-20 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS10180 5936f4ffbd39529e0e94629ac7bafad6 1004 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 940 954 1.1E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS10180 5936f4ffbd39529e0e94629ac7bafad6 1004 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 954 970 1.1E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS10180 5936f4ffbd39529e0e94629ac7bafad6 1004 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 970 982 1.1E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS10180 5936f4ffbd39529e0e94629ac7bafad6 1004 Gene3D G3DSA:1.25.40.10 556 653 0.0029 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS10180 5936f4ffbd39529e0e94629ac7bafad6 1004 SUPERFAMILY SSF48452 475 672 9.49E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS10180 5936f4ffbd39529e0e94629ac7bafad6 1004 SUPERFAMILY SSF52540 145 272 4.82E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS10180 5936f4ffbd39529e0e94629ac7bafad6 1004 SUPERFAMILY SSF52540 13 76 4.82E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS10180 5936f4ffbd39529e0e94629ac7bafad6 1004 Pfam PF13191 AAA ATPase domain 12 202 1.1E-26 T 28-03-2018 CU254_RS10180 5936f4ffbd39529e0e94629ac7bafad6 1004 Gene3D G3DSA:1.25.40.10 394 555 1.7E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS10180 5936f4ffbd39529e0e94629ac7bafad6 1004 ProSitePatterns PS00622 LuxR-type HTH domain signature. 954 981 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS10180 5936f4ffbd39529e0e94629ac7bafad6 1004 Gene3D G3DSA:1.10.10.10 870 1004 5.2E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS07275 b072a6dc3d27a5e7ae864df02752950a 413 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 147 402 8.3E-70 T 28-03-2018 IPR024516 Mammalian cell entry, C-terminal CU254_RS07275 b072a6dc3d27a5e7ae864df02752950a 413 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 12 297 1.6E-52 T 28-03-2018 IPR005693 Virulence factor Mce protein CU254_RS07275 b072a6dc3d27a5e7ae864df02752950a 413 Pfam PF02470 MlaD protein 40 115 6.8E-8 T 28-03-2018 IPR003399 Mce/MlaD CU254_RS30820 d0bbffc72247cbe33b8047c4836658e7 726 Pfam PF09056 Prokaryotic phospholipase A2 106 183 1.0E-8 T 28-03-2018 IPR015141 Phospholipase A2, prokaryotic/fungal CU254_RS30820 d0bbffc72247cbe33b8047c4836658e7 726 Gene3D G3DSA:1.20.90.10 95 188 9.6E-12 T 28-03-2018 IPR016090 Phospholipase A2 domain GO:0004623|GO:0006644|GO:0050482 KEGG: 00564+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 CU254_RS30820 d0bbffc72247cbe33b8047c4836658e7 726 SUPERFAMILY SSF48619 105 183 2.59E-9 T 28-03-2018 IPR016090 Phospholipase A2 domain GO:0004623|GO:0006644|GO:0050482 KEGG: 00564+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 CU254_RS30820 d0bbffc72247cbe33b8047c4836658e7 726 Gene3D G3DSA:1.20.1070.10 345 572 0.0015 T 28-03-2018 CU254_RS24935 1a3df5485b81ffbca3d960859495c698 339 Pfam PF01170 Putative RNA methylase family UPF0020 130 258 4.3E-5 T 28-03-2018 IPR000241 Putative RNA methylase domain KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CU254_RS24935 1a3df5485b81ffbca3d960859495c698 339 Gene3D G3DSA:3.40.50.150 93 335 4.0E-22 T 28-03-2018 CU254_RS24935 1a3df5485b81ffbca3d960859495c698 339 SUPERFAMILY SSF53335 222 303 5.83E-15 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS24935 1a3df5485b81ffbca3d960859495c698 339 SUPERFAMILY SSF53335 111 172 5.83E-15 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS35310 31a95081913821c468a1fa5c9e62f180 285 Gene3D G3DSA:3.40.50.300 1 285 5.0E-67 T 28-03-2018 CU254_RS35310 31a95081913821c468a1fa5c9e62f180 285 Pfam PF00005 ABC transporter 25 166 1.0E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS35310 31a95081913821c468a1fa5c9e62f180 285 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS35310 31a95081913821c468a1fa5c9e62f180 285 SMART SM00382 33 215 5.2E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS35310 31a95081913821c468a1fa5c9e62f180 285 SUPERFAMILY SSF52540 4 230 1.14E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS24595 ebfde91bc16e20b39b77a497352367f0 468 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 7 52 5.4E-6 T 28-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CU254_RS24595 ebfde91bc16e20b39b77a497352367f0 468 Gene3D G3DSA:3.40.50.720 1 90 1.1E-16 T 28-03-2018 CU254_RS24595 ebfde91bc16e20b39b77a497352367f0 468 Pfam PF08245 Mur ligase middle domain 111 292 1.2E-28 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CU254_RS24595 ebfde91bc16e20b39b77a497352367f0 468 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 6 456 31.895 T 28-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CU254_RS24595 ebfde91bc16e20b39b77a497352367f0 468 Gene3D G3DSA:3.40.1190.10 95 315 2.7E-56 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CU254_RS24595 ebfde91bc16e20b39b77a497352367f0 468 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 7 454 4.0E-116 T 28-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CU254_RS24595 ebfde91bc16e20b39b77a497352367f0 468 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 109 132 - T 28-03-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 CU254_RS24595 ebfde91bc16e20b39b77a497352367f0 468 Gene3D G3DSA:3.90.190.20 317 455 4.0E-33 T 28-03-2018 CU254_RS24595 ebfde91bc16e20b39b77a497352367f0 468 SUPERFAMILY SSF51984 2 90 8.37E-15 T 28-03-2018 CU254_RS24595 ebfde91bc16e20b39b77a497352367f0 468 SUPERFAMILY SSF53244 313 456 1.88E-35 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CU254_RS24595 ebfde91bc16e20b39b77a497352367f0 468 SUPERFAMILY SSF53623 104 309 1.7E-50 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CU254_RS33090 7f14d5a3cf9ff9bb297a087762cc5754 1079 Pfam PF00486 Transcriptional regulatory protein, C terminal 33 104 2.3E-8 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS33090 7f14d5a3cf9ff9bb297a087762cc5754 1079 Pfam PF13191 AAA ATPase domain 284 434 2.9E-17 T 28-03-2018 CU254_RS33090 7f14d5a3cf9ff9bb297a087762cc5754 1079 Gene3D G3DSA:1.25.40.10 108 272 3.7E-23 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS33090 7f14d5a3cf9ff9bb297a087762cc5754 1079 SUPERFAMILY SSF46894 11 103 2.52E-13 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS33090 7f14d5a3cf9ff9bb297a087762cc5754 1079 Gene3D G3DSA:1.25.40.10 665 833 3.1E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS33090 7f14d5a3cf9ff9bb297a087762cc5754 1079 Gene3D G3DSA:1.10.10.10 6 107 3.1E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS33090 7f14d5a3cf9ff9bb297a087762cc5754 1079 Pfam PF03704 Bacterial transcriptional activator domain 111 255 2.0E-34 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CU254_RS33090 7f14d5a3cf9ff9bb297a087762cc5754 1079 SUPERFAMILY SSF52540 277 512 5.62E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS33090 7f14d5a3cf9ff9bb297a087762cc5754 1079 Gene3D G3DSA:3.40.50.300 276 452 6.5E-9 T 28-03-2018 CU254_RS33090 7f14d5a3cf9ff9bb297a087762cc5754 1079 SMART SM00862 24 104 6.8E-13 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS33090 7f14d5a3cf9ff9bb297a087762cc5754 1079 SMART SM01043 111 255 2.9E-36 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CU254_RS33090 7f14d5a3cf9ff9bb297a087762cc5754 1079 SUPERFAMILY SSF48452 106 280 3.22E-30 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS33090 7f14d5a3cf9ff9bb297a087762cc5754 1079 Gene3D G3DSA:1.25.40.10 834 1079 4.6E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS05445 0f20e05db0fa24c3f892aa2e0493fe5b 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 2.4E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS05445 0f20e05db0fa24c3f892aa2e0493fe5b 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 2.4E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS05445 0f20e05db0fa24c3f892aa2e0493fe5b 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.4E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS05445 0f20e05db0fa24c3f892aa2e0493fe5b 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 2.4E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS05445 0f20e05db0fa24c3f892aa2e0493fe5b 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 2.4E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS05445 0f20e05db0fa24c3f892aa2e0493fe5b 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 2.4E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS05445 0f20e05db0fa24c3f892aa2e0493fe5b 264 Gene3D G3DSA:3.40.50.720 44 261 3.2E-46 T 28-03-2018 CU254_RS05445 0f20e05db0fa24c3f892aa2e0493fe5b 264 Gene3D G3DSA:3.40.50.720 1 43 1.1E-9 T 28-03-2018 CU254_RS05445 0f20e05db0fa24c3f892aa2e0493fe5b 264 SUPERFAMILY SSF51735 6 258 1.44E-61 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS05445 0f20e05db0fa24c3f892aa2e0493fe5b 264 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 258 1.0E-43 T 28-03-2018 CU254_RS04240 11c74811f51a033acb796652827714e5 202 SUPERFAMILY SSF50475 10 185 5.15E-31 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS04240 11c74811f51a033acb796652827714e5 202 Pfam PF04299 Putative FMN-binding domain 7 161 3.2E-25 T 28-03-2018 IPR007396 Transcriptional regulator PAI 2-type CU254_RS04240 11c74811f51a033acb796652827714e5 202 Gene3D G3DSA:2.30.110.10 1 201 2.5E-42 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS35150 703b0214600b4597f105fb9d6e7487fd 323 SUPERFAMILY SSF47240 23 283 3.03E-50 T 28-03-2018 IPR009078 Ferritin-like superfamily CU254_RS35150 703b0214600b4597f105fb9d6e7487fd 323 Pfam PF00268 Ribonucleotide reductase, small chain 32 280 4.2E-13 T 28-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CU254_RS35150 703b0214600b4597f105fb9d6e7487fd 323 Gene3D G3DSA:1.10.620.20 3 295 7.8E-63 T 28-03-2018 CU254_RS26195 cac8ced320f4e946f114a62d3884c2ff 151 Pfam PF02575 YbaB/EbfC DNA-binding family 20 99 2.6E-12 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CU254_RS26195 cac8ced320f4e946f114a62d3884c2ff 151 Gene3D G3DSA:3.30.1310.10 15 101 4.6E-17 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CU254_RS26195 cac8ced320f4e946f114a62d3884c2ff 151 SUPERFAMILY SSF82607 21 101 3.92E-9 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CU254_RS13800 57c4312d9964bf0136a29b6e0a3463f3 146 Pfam PF01475 Ferric uptake regulator family 11 125 2.0E-19 T 28-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CU254_RS13800 57c4312d9964bf0136a29b6e0a3463f3 146 SUPERFAMILY SSF46785 5 133 6.99E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS13800 57c4312d9964bf0136a29b6e0a3463f3 146 Gene3D G3DSA:1.10.10.10 4 88 1.2E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS20945 40e0802a1c5614edd80e490d5c6ab339 332 SUPERFAMILY SSF103481 54 150 1.96E-12 T 28-03-2018 CU254_RS20945 40e0802a1c5614edd80e490d5c6ab339 332 SUPERFAMILY SSF103481 207 301 2.88E-12 T 28-03-2018 CU254_RS20945 40e0802a1c5614edd80e490d5c6ab339 332 Pfam PF00892 EamA-like transporter family 25 149 5.4E-13 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CU254_RS20945 40e0802a1c5614edd80e490d5c6ab339 332 Pfam PF00892 EamA-like transporter family 165 297 8.7E-11 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CU254_RS07420 175396f2d4144087e7187665f1d145cd 235 SUPERFAMILY SSF46785 11 85 5.0E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS07420 175396f2d4144087e7187665f1d145cd 235 SUPERFAMILY SSF48008 102 233 9.42E-22 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS07420 175396f2d4144087e7187665f1d145cd 235 SMART SM00895 104 225 1.9E-14 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS07420 175396f2d4144087e7187665f1d145cd 235 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 70 1.2E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS07420 175396f2d4144087e7187665f1d145cd 235 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 54 1.2E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS07420 175396f2d4144087e7187665f1d145cd 235 Gene3D G3DSA:1.10.10.10 11 84 1.0E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS07420 175396f2d4144087e7187665f1d145cd 235 SMART SM00345 21 82 1.4E-19 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS07420 175396f2d4144087e7187665f1d145cd 235 Gene3D G3DSA:1.20.120.530 86 235 5.5E-25 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS07420 175396f2d4144087e7187665f1d145cd 235 Pfam PF07729 FCD domain 105 224 9.1E-18 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS07420 175396f2d4144087e7187665f1d145cd 235 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 82 9.6E-19 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS14220 30149576117d0c34964ade1345e1658e 191 Pfam PF13676 TIR domain 6 94 1.6E-13 T 28-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 CU254_RS14220 30149576117d0c34964ade1345e1658e 191 SMART SM00255 3 162 1.2E-4 T 28-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 CU254_RS14220 30149576117d0c34964ade1345e1658e 191 SUPERFAMILY SSF52200 2 139 3.92E-18 T 28-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 CU254_RS14220 30149576117d0c34964ade1345e1658e 191 Gene3D G3DSA:3.40.50.10140 1 164 1.4E-21 T 28-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 CU254_RS13200 3ff4811241d8eaf8e978c00364bbe7f0 320 TIGRFAM TIGR01136 cysKM: cysteine synthase 8 301 5.7E-108 T 28-03-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 CU254_RS13200 3ff4811241d8eaf8e978c00364bbe7f0 320 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 32 50 - T 28-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 CU254_RS13200 3ff4811241d8eaf8e978c00364bbe7f0 320 Gene3D G3DSA:3.40.50.1100 134 306 4.0E-48 T 28-03-2018 CU254_RS13200 3ff4811241d8eaf8e978c00364bbe7f0 320 TIGRFAM TIGR01139 cysK: cysteine synthase A 9 301 3.8E-111 T 28-03-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 CU254_RS13200 3ff4811241d8eaf8e978c00364bbe7f0 320 SUPERFAMILY SSF53686 2 303 1.83E-86 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CU254_RS13200 3ff4811241d8eaf8e978c00364bbe7f0 320 Gene3D G3DSA:3.40.50.1100 21 133 3.1E-31 T 28-03-2018 CU254_RS13200 3ff4811241d8eaf8e978c00364bbe7f0 320 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 8 291 1.9E-61 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CU254_RS04090 44727bed60e1dfb8fcfa596d037f14cc 1057 Gene3D G3DSA:3.40.50.300 9 320 4.2E-34 T 28-03-2018 CU254_RS04090 44727bed60e1dfb8fcfa596d037f14cc 1057 Gene3D G3DSA:3.90.320.10 748 969 3.0E-14 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 CU254_RS04090 44727bed60e1dfb8fcfa596d037f14cc 1057 Pfam PF12705 PD-(D/E)XK nuclease superfamily 802 1046 9.6E-40 T 28-03-2018 CU254_RS04090 44727bed60e1dfb8fcfa596d037f14cc 1057 Pfam PF13361 UvrD-like helicase C-terminal domain 352 700 1.7E-16 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CU254_RS04090 44727bed60e1dfb8fcfa596d037f14cc 1057 Pfam PF00580 UvrD/REP helicase N-terminal domain 24 309 2.7E-34 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CU254_RS04090 44727bed60e1dfb8fcfa596d037f14cc 1057 SUPERFAMILY SSF52540 11 718 1.15E-84 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS04090 44727bed60e1dfb8fcfa596d037f14cc 1057 Gene3D G3DSA:3.40.50.300 343 729 1.0E-43 T 28-03-2018 CU254_RS33775 368c14724450e234da2c4a463b352072 225 SUPERFAMILY SSF48498 83 182 2.31E-9 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS33775 368c14724450e234da2c4a463b352072 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 8.5E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS33775 368c14724450e234da2c4a463b352072 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 8.5E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS33775 368c14724450e234da2c4a463b352072 225 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 103 182 4.2E-7 T 28-03-2018 CU254_RS33775 368c14724450e234da2c4a463b352072 225 Gene3D G3DSA:1.10.10.60 2 60 5.8E-20 T 28-03-2018 CU254_RS33775 368c14724450e234da2c4a463b352072 225 SUPERFAMILY SSF46689 2 83 3.08E-19 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS33775 368c14724450e234da2c4a463b352072 225 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 2.5E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS33775 368c14724450e234da2c4a463b352072 225 Gene3D G3DSA:1.10.357.10 61 210 2.6E-13 T 28-03-2018 CU254_RS33345 7eb71f614edcc0ef93c2a485a9209f62 1102 Pfam PF00326 Prolyl oligopeptidase family 442 644 2.8E-42 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CU254_RS33345 7eb71f614edcc0ef93c2a485a9209f62 1102 SUPERFAMILY SSF56601 654 992 1.53E-76 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CU254_RS33345 7eb71f614edcc0ef93c2a485a9209f62 1102 Gene3D G3DSA:3.40.710.10 648 996 6.2E-82 T 28-03-2018 CU254_RS33345 7eb71f614edcc0ef93c2a485a9209f62 1102 SUPERFAMILY SSF82171 13 381 1.57E-42 T 28-03-2018 CU254_RS33345 7eb71f614edcc0ef93c2a485a9209f62 1102 Gene3D G3DSA:3.40.50.1820 378 647 9.8E-46 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS33345 7eb71f614edcc0ef93c2a485a9209f62 1102 Pfam PF00144 Beta-lactamase 656 979 2.2E-63 T 28-03-2018 IPR001466 Beta-lactamase-related CU254_RS33345 7eb71f614edcc0ef93c2a485a9209f62 1102 Pfam PF07676 WD40-like Beta Propeller Repeat 57 91 9.6E-7 T 28-03-2018 IPR011659 WD40-like Beta Propeller CU254_RS33345 7eb71f614edcc0ef93c2a485a9209f62 1102 Pfam PF07676 WD40-like Beta Propeller Repeat 109 125 1.0E-4 T 28-03-2018 IPR011659 WD40-like Beta Propeller CU254_RS33345 7eb71f614edcc0ef93c2a485a9209f62 1102 Pfam PF07676 WD40-like Beta Propeller Repeat 183 199 0.02 T 28-03-2018 IPR011659 WD40-like Beta Propeller CU254_RS33345 7eb71f614edcc0ef93c2a485a9209f62 1102 Pfam PF07676 WD40-like Beta Propeller Repeat 19 33 0.088 T 28-03-2018 IPR011659 WD40-like Beta Propeller CU254_RS33345 7eb71f614edcc0ef93c2a485a9209f62 1102 Gene3D G3DSA:2.130.10.150 14 220 6.8E-36 T 28-03-2018 CU254_RS33345 7eb71f614edcc0ef93c2a485a9209f62 1102 SUPERFAMILY SSF53474 390 641 1.49E-56 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS33345 7eb71f614edcc0ef93c2a485a9209f62 1102 Gene3D G3DSA:2.140.10.30 221 377 3.2E-12 T 28-03-2018 CU254_RS15305 4ae007e112d279c7f7d1b9c3939e29c7 452 Pfam PF07690 Major Facilitator Superfamily 49 301 7.1E-22 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS15305 4ae007e112d279c7f7d1b9c3939e29c7 452 Gene3D G3DSA:1.20.1250.20 239 443 5.4E-19 T 28-03-2018 CU254_RS15305 4ae007e112d279c7f7d1b9c3939e29c7 452 Gene3D G3DSA:1.20.1250.20 21 234 2.9E-24 T 28-03-2018 CU254_RS15305 4ae007e112d279c7f7d1b9c3939e29c7 452 SUPERFAMILY SSF103473 16 436 1.83E-60 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS29030 3b666eb40fb8f1a5a16b433d351444f4 403 Pfam PF02371 Transposase IS116/IS110/IS902 family 271 356 7.5E-23 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CU254_RS29030 3b666eb40fb8f1a5a16b433d351444f4 403 Gene3D G3DSA:3.30.420.40 4 246 9.3E-5 T 28-03-2018 CU254_RS29030 3b666eb40fb8f1a5a16b433d351444f4 403 Pfam PF01548 Transposase 9 163 1.1E-43 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CU254_RS11070 faf756426f347b620bdeaeefeb6dd1eb 360 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 26 359 5.7E-129 T 28-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CU254_RS11070 faf756426f347b620bdeaeefeb6dd1eb 360 Gene3D G3DSA:3.20.20.210 24 360 3.0E-108 T 28-03-2018 CU254_RS11070 faf756426f347b620bdeaeefeb6dd1eb 360 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 25 360 45.647 T 28-03-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CU254_RS11070 faf756426f347b620bdeaeefeb6dd1eb 360 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 41 50 - T 28-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CU254_RS11070 faf756426f347b620bdeaeefeb6dd1eb 360 SUPERFAMILY SSF51726 26 359 1.74E-106 T 28-03-2018 CU254_RS11070 faf756426f347b620bdeaeefeb6dd1eb 360 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 28 359 1.1E-122 T 28-03-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CU254_RS11070 faf756426f347b620bdeaeefeb6dd1eb 360 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 158 174 - T 28-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CU254_RS04630 ba160d097610c3ebd148f3c7765af530 1080 TIGRFAM TIGR02243 TIGR02243: putative baseplate assembly protein 484 968 8.9E-61 T 28-03-2018 IPR011749 Conserved hypothetical protein CHP02243 CU254_RS04630 ba160d097610c3ebd148f3c7765af530 1080 Gene3D G3DSA:3.10.350.10 1016 1054 1.2E-6 T 28-03-2018 CU254_RS04630 ba160d097610c3ebd148f3c7765af530 1080 Pfam PF01476 LysM domain 1018 1052 4.3E-4 T 28-03-2018 IPR018392 LysM domain CU254_RS04630 ba160d097610c3ebd148f3c7765af530 1080 Pfam PF04865 Baseplate J-like protein 770 932 1.1E-5 T 28-03-2018 IPR006949 Baseplate protein J-like CU254_RS24950 3cfb299a47ccfd908f5ea8eec7be1aa8 97 SUPERFAMILY SSF103007 1 95 5.23E-31 T 28-03-2018 IPR007546 Protein of unknown function DUF503 CU254_RS24950 3cfb299a47ccfd908f5ea8eec7be1aa8 97 Gene3D G3DSA:3.30.70.1120 2 92 4.9E-34 T 28-03-2018 CU254_RS24950 3cfb299a47ccfd908f5ea8eec7be1aa8 97 Pfam PF04456 Protein of unknown function (DUF503) 3 89 3.8E-32 T 28-03-2018 IPR007546 Protein of unknown function DUF503 CU254_RS11340 914373cdbcbf8128c3eeb2e5cc9e0d10 300 SUPERFAMILY SSF51735 121 289 5.65E-26 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS11340 914373cdbcbf8128c3eeb2e5cc9e0d10 300 SUPERFAMILY SSF53223 20 119 6.91E-25 T 28-03-2018 CU254_RS11340 914373cdbcbf8128c3eeb2e5cc9e0d10 300 Gene3D G3DSA:3.40.50.720 132 294 1.5E-23 T 28-03-2018 CU254_RS11340 914373cdbcbf8128c3eeb2e5cc9e0d10 300 Gene3D G3DSA:3.40.50.10860 17 131 8.5E-38 T 28-03-2018 CU254_RS11340 914373cdbcbf8128c3eeb2e5cc9e0d10 300 TIGRFAM TIGR01809 Shik-DH-AROM: shikimate-5-dehydrogenase 19 287 1.9E-68 T 28-03-2018 IPR010110 Shikimate dehydrogenase, AroM-type GO:0004764|GO:0005737|GO:0055114 KEGG: 00400+4.2.1.10+1.1.1.25+2.7.1.71+2.5.1.19+4.2.3.4|MetaCyc: PWY-6163|MetaCyc: PWY-6164|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CU254_RS11340 914373cdbcbf8128c3eeb2e5cc9e0d10 300 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 25 107 1.8E-21 T 28-03-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CU254_RS25795 226e76c2055f83e3a4a136c179352adc 60 Pfam PF00741 Gas vesicle protein 12 50 8.9E-15 T 28-03-2018 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 CU254_RS06830 99727da022ee23d769ad9cd694aa3b24 302 SUPERFAMILY SSF51735 94 268 3.65E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS06830 99727da022ee23d769ad9cd694aa3b24 302 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 101 267 1.2E-44 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CU254_RS06830 99727da022ee23d769ad9cd694aa3b24 302 Gene3D G3DSA:3.40.50.720 3 105 1.8E-12 T 28-03-2018 CU254_RS06830 99727da022ee23d769ad9cd694aa3b24 302 Gene3D G3DSA:3.40.50.720 106 270 6.6E-48 T 28-03-2018 CU254_RS06830 99727da022ee23d769ad9cd694aa3b24 302 SUPERFAMILY SSF52283 35 122 5.1E-6 T 28-03-2018 CU254_RS06500 762d2e574ed33b5d6cf31244404998a3 270 SUPERFAMILY SSF52540 9 247 5.33E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS06500 762d2e574ed33b5d6cf31244404998a3 270 Pfam PF00005 ABC transporter 32 181 1.8E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS06500 762d2e574ed33b5d6cf31244404998a3 270 Gene3D G3DSA:3.40.50.300 5 264 7.0E-42 T 28-03-2018 CU254_RS06500 762d2e574ed33b5d6cf31244404998a3 270 SMART SM00382 39 240 3.8E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS07450 59d25f19de75c3ebf8bb4a6e0fa9ef8d 414 Gene3D G3DSA:3.50.50.60 127 186 6.5E-16 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS07450 59d25f19de75c3ebf8bb4a6e0fa9ef8d 414 Gene3D G3DSA:3.50.50.60 187 321 1.3E-20 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS07450 59d25f19de75c3ebf8bb4a6e0fa9ef8d 414 Gene3D G3DSA:3.30.390.30 323 411 3.2E-19 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CU254_RS07450 59d25f19de75c3ebf8bb4a6e0fa9ef8d 414 SUPERFAMILY SSF51905 2 191 1.16E-44 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS07450 59d25f19de75c3ebf8bb4a6e0fa9ef8d 414 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 304 9.4E-57 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS07450 59d25f19de75c3ebf8bb4a6e0fa9ef8d 414 SUPERFAMILY SSF55424 316 409 5.49E-14 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CU254_RS07450 59d25f19de75c3ebf8bb4a6e0fa9ef8d 414 SUPERFAMILY SSF51905 146 313 1.1E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS07450 59d25f19de75c3ebf8bb4a6e0fa9ef8d 414 Gene3D G3DSA:3.50.50.60 1 126 6.3E-17 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS07450 59d25f19de75c3ebf8bb4a6e0fa9ef8d 414 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 233 247 1.5E-16 T 28-03-2018 CU254_RS07450 59d25f19de75c3ebf8bb4a6e0fa9ef8d 414 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 274 281 1.5E-16 T 28-03-2018 CU254_RS07450 59d25f19de75c3ebf8bb4a6e0fa9ef8d 414 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 172 1.5E-16 T 28-03-2018 CU254_RS07450 59d25f19de75c3ebf8bb4a6e0fa9ef8d 414 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 1.5E-16 T 28-03-2018 CU254_RS07450 59d25f19de75c3ebf8bb4a6e0fa9ef8d 414 Pfam PF14759 Reductase C-terminal 323 406 4.7E-6 T 28-03-2018 IPR028202 Reductase, C-terminal CU254_RS07450 59d25f19de75c3ebf8bb4a6e0fa9ef8d 414 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 3.7E-26 T 28-03-2018 CU254_RS07450 59d25f19de75c3ebf8bb4a6e0fa9ef8d 414 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 232 248 3.7E-26 T 28-03-2018 CU254_RS07450 59d25f19de75c3ebf8bb4a6e0fa9ef8d 414 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 3.7E-26 T 28-03-2018 CU254_RS07450 59d25f19de75c3ebf8bb4a6e0fa9ef8d 414 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 3.7E-26 T 28-03-2018 CU254_RS07450 59d25f19de75c3ebf8bb4a6e0fa9ef8d 414 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 259 281 3.7E-26 T 28-03-2018 CU254_RS24335 22588a80ae8cb0d282736715475456cc 451 PIRSF PIRSF010256 1 451 1.9E-110 T 28-03-2018 IPR011195 Uncharacterised conserved protein UCP010256 CU254_RS24335 22588a80ae8cb0d282736715475456cc 451 Gene3D G3DSA:3.40.50.410 245 409 2.3E-6 T 28-03-2018 IPR002035 von Willebrand factor, type A CU254_RS24335 22588a80ae8cb0d282736715475456cc 451 SUPERFAMILY SSF53300 279 410 1.72E-6 T 28-03-2018 IPR002035 von Willebrand factor, type A CU254_RS24335 22588a80ae8cb0d282736715475456cc 451 Pfam PF05762 VWA domain containing CoxE-like protein 223 441 1.3E-48 T 28-03-2018 IPR008912 Uncharacterised protein family CoxE-like CU254_RS37780 6dbb25f6a21feefbe428b912456caae2 253 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 28 239 1.0E-54 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CU254_RS37780 6dbb25f6a21feefbe428b912456caae2 253 Gene3D G3DSA:3.40.190.10 23 110 3.3E-22 T 28-03-2018 CU254_RS37780 6dbb25f6a21feefbe428b912456caae2 253 SMART SM00062 27 244 4.0E-54 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CU254_RS37780 6dbb25f6a21feefbe428b912456caae2 253 Gene3D G3DSA:3.40.190.10 111 213 6.6E-20 T 28-03-2018 CU254_RS37780 6dbb25f6a21feefbe428b912456caae2 253 SUPERFAMILY SSF53850 1 240 8.62E-58 T 28-03-2018 CU254_RS09350 57f90c087460b495edb7ccd2e3994486 458 Pfam PF16952 Glutamine synthetase N-terminal domain 22 121 5.8E-10 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CU254_RS09350 57f90c087460b495edb7ccd2e3994486 458 Gene3D G3DSA:3.30.590.10 120 454 1.3E-95 T 28-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CU254_RS09350 57f90c087460b495edb7ccd2e3994486 458 SUPERFAMILY SSF54368 23 122 5.1E-7 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CU254_RS09350 57f90c087460b495edb7ccd2e3994486 458 SMART SM01230 123 368 2.9E-75 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CU254_RS09350 57f90c087460b495edb7ccd2e3994486 458 Gene3D G3DSA:3.10.20.70 23 119 1.5E-18 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CU254_RS09350 57f90c087460b495edb7ccd2e3994486 458 SUPERFAMILY SSF55931 123 443 5.49E-82 T 28-03-2018 CU254_RS09350 57f90c087460b495edb7ccd2e3994486 458 Pfam PF00120 Glutamine synthetase, catalytic domain 124 442 1.4E-77 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CU254_RS15855 1beaa61e48f72f207adb25f3fcb425ab 312 SUPERFAMILY SSF53756 1 306 7.85E-63 T 28-03-2018 CU254_RS15855 1beaa61e48f72f207adb25f3fcb425ab 312 Gene3D G3DSA:3.40.50.2000 1 140 7.6E-15 T 28-03-2018 CU254_RS15855 1beaa61e48f72f207adb25f3fcb425ab 312 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 151 262 2.9E-30 T 28-03-2018 IPR002201 Glycosyl transferase, family 9 GO:0008152|GO:0016757 CU254_RS15855 1beaa61e48f72f207adb25f3fcb425ab 312 Gene3D G3DSA:3.40.50.2000 144 310 2.8E-42 T 28-03-2018 CU254_RS30940 ad1a4dd644b9a0670ee6fd637ad2db20 229 Pfam PF00072 Response regulator receiver domain 5 114 1.0E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS30940 ad1a4dd644b9a0670ee6fd637ad2db20 229 Gene3D G3DSA:1.10.10.10 119 228 6.9E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS30940 ad1a4dd644b9a0670ee6fd637ad2db20 229 SMART SM00862 146 222 8.7E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS30940 ad1a4dd644b9a0670ee6fd637ad2db20 229 SMART SM00448 3 113 1.8E-44 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS30940 ad1a4dd644b9a0670ee6fd637ad2db20 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 222 1.9E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS30940 ad1a4dd644b9a0670ee6fd637ad2db20 229 SUPERFAMILY SSF52172 4 171 2.56E-41 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS30940 ad1a4dd644b9a0670ee6fd637ad2db20 229 Gene3D G3DSA:3.40.50.2300 2 118 1.2E-37 T 28-03-2018 CU254_RS32220 12a681e5be0f934a6a15eab4fab37272 113 Pfam PF03551 Transcriptional regulator PadR-like family 17 88 5.0E-20 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CU254_RS32220 12a681e5be0f934a6a15eab4fab37272 113 SUPERFAMILY SSF46785 6 105 1.3E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS32220 12a681e5be0f934a6a15eab4fab37272 113 Gene3D G3DSA:1.10.10.10 1 108 1.8E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS21675 fa4ee25d7cd1a6e8dd4b1bc7e19c4770 275 SUPERFAMILY SSF48452 105 260 1.35E-35 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS21675 fa4ee25d7cd1a6e8dd4b1bc7e19c4770 275 SUPERFAMILY SSF46894 5 100 2.92E-12 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS21675 fa4ee25d7cd1a6e8dd4b1bc7e19c4770 275 Gene3D G3DSA:1.10.10.10 1 103 4.6E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS21675 fa4ee25d7cd1a6e8dd4b1bc7e19c4770 275 SMART SM01043 107 252 7.2E-48 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CU254_RS21675 fa4ee25d7cd1a6e8dd4b1bc7e19c4770 275 Pfam PF00486 Transcriptional regulatory protein, C terminal 30 99 1.3E-9 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS21675 fa4ee25d7cd1a6e8dd4b1bc7e19c4770 275 Gene3D G3DSA:1.25.40.10 104 261 8.3E-24 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS21675 fa4ee25d7cd1a6e8dd4b1bc7e19c4770 275 Pfam PF03704 Bacterial transcriptional activator domain 107 252 6.3E-42 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CU254_RS21675 fa4ee25d7cd1a6e8dd4b1bc7e19c4770 275 SMART SM00862 19 100 2.8E-6 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS08870 80763ac40a23e1f3740a78acba74521b 319 Pfam PF01965 DJ-1/PfpI family 5 173 1.3E-12 T 28-03-2018 IPR002818 DJ-1/PfpI CU254_RS08870 80763ac40a23e1f3740a78acba74521b 319 Gene3D G3DSA:1.10.10.60 214 268 1.4E-13 T 28-03-2018 CU254_RS08870 80763ac40a23e1f3740a78acba74521b 319 SUPERFAMILY SSF46689 267 317 3.58E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS08870 80763ac40a23e1f3740a78acba74521b 319 SUPERFAMILY SSF52317 5 194 2.79E-40 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS08870 80763ac40a23e1f3740a78acba74521b 319 Gene3D G3DSA:3.40.50.880 2 213 1.4E-45 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS08870 80763ac40a23e1f3740a78acba74521b 319 SMART SM00342 231 314 4.4E-26 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS08870 80763ac40a23e1f3740a78acba74521b 319 SUPERFAMILY SSF46689 214 265 3.94E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS08870 80763ac40a23e1f3740a78acba74521b 319 Pfam PF12833 Helix-turn-helix domain 237 315 4.8E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS08870 80763ac40a23e1f3740a78acba74521b 319 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 268 310 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CU254_RS08870 80763ac40a23e1f3740a78acba74521b 319 Gene3D G3DSA:1.10.10.60 269 319 1.1E-12 T 28-03-2018 CU254_RS11390 65655cbd54325498cc731b68cfc54e82 141 Gene3D G3DSA:2.102.10.10 40 141 9.9E-23 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CU254_RS11390 65655cbd54325498cc731b68cfc54e82 141 SUPERFAMILY SSF50022 45 139 9.95E-27 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CU254_RS11390 65655cbd54325498cc731b68cfc54e82 141 Pfam PF00355 Rieske [2Fe-2S] domain 47 128 3.9E-16 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CU254_RS11390 65655cbd54325498cc731b68cfc54e82 141 PRINTS PR00162 Rieske 2Fe-2S subunit signature 114 126 1.6E-8 T 28-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 CU254_RS11390 65655cbd54325498cc731b68cfc54e82 141 PRINTS PR00162 Rieske 2Fe-2S subunit signature 81 92 1.6E-8 T 28-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 CU254_RS11390 65655cbd54325498cc731b68cfc54e82 141 PRINTS PR00162 Rieske 2Fe-2S subunit signature 101 113 1.6E-8 T 28-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 CU254_RS40970 cfca1e6258b9d27105e2c190075e822b 138 ProSitePatterns PS00893 Nudix box signature. 35 56 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CU254_RS40970 cfca1e6258b9d27105e2c190075e822b 138 Gene3D G3DSA:3.90.79.10 2 137 2.1E-25 T 28-03-2018 CU254_RS40970 cfca1e6258b9d27105e2c190075e822b 138 SUPERFAMILY SSF55811 6 132 1.02E-29 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CU254_RS40970 cfca1e6258b9d27105e2c190075e822b 138 Pfam PF00293 NUDIX domain 13 119 6.6E-17 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CU254_RS40970 cfca1e6258b9d27105e2c190075e822b 138 PRINTS PR00502 NUDIX hydrolase family signature 30 44 1.3E-8 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CU254_RS40970 cfca1e6258b9d27105e2c190075e822b 138 PRINTS PR00502 NUDIX hydrolase family signature 44 59 1.3E-8 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CU254_RS30660 a936ecc9742dee02036e6ed9237adf0c 181 SUPERFAMILY SSF53597 1 178 4.84E-32 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CU254_RS30660 a936ecc9742dee02036e6ed9237adf0c 181 Pfam PF01872 RibD C-terminal domain 2 172 1.1E-28 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CU254_RS30660 a936ecc9742dee02036e6ed9237adf0c 181 Gene3D G3DSA:3.40.430.10 2 176 1.7E-36 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CU254_RS32655 3a201c40204c570d0d6659871ca1acc5 642 Gene3D G3DSA:2.40.50.250 515 605 7.9E-36 T 28-03-2018 CU254_RS32655 3a201c40204c570d0d6659871ca1acc5 642 SMART SM00838 428 516 0.0025 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CU254_RS32655 3a201c40204c570d0d6659871ca1acc5 642 SUPERFAMILY SSF50447 184 332 5.52E-31 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CU254_RS32655 3a201c40204c570d0d6659871ca1acc5 642 Gene3D G3DSA:3.30.70.240 435 512 6.1E-17 T 28-03-2018 CU254_RS32655 3a201c40204c570d0d6659871ca1acc5 642 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 22 630 1.9E-273 T 28-03-2018 IPR006298 GTP-binding protein TypA GO:0005525 CU254_RS32655 3a201c40204c570d0d6659871ca1acc5 642 Gene3D G3DSA:3.30.70.870 334 434 3.8E-26 T 28-03-2018 CU254_RS32655 3a201c40204c570d0d6659871ca1acc5 642 PRINTS PR00315 GTP-binding elongation factor signature 144 153 3.5E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CU254_RS32655 3a201c40204c570d0d6659871ca1acc5 642 PRINTS PR00315 GTP-binding elongation factor signature 92 102 3.5E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CU254_RS32655 3a201c40204c570d0d6659871ca1acc5 642 PRINTS PR00315 GTP-binding elongation factor signature 24 37 3.5E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CU254_RS32655 3a201c40204c570d0d6659871ca1acc5 642 PRINTS PR00315 GTP-binding elongation factor signature 68 76 3.5E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CU254_RS32655 3a201c40204c570d0d6659871ca1acc5 642 PRINTS PR00315 GTP-binding elongation factor signature 108 119 3.5E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CU254_RS32655 3a201c40204c570d0d6659871ca1acc5 642 Pfam PF00009 Elongation factor Tu GTP binding domain 22 227 1.0E-52 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CU254_RS32655 3a201c40204c570d0d6659871ca1acc5 642 Pfam PF00679 Elongation factor G C-terminus 429 513 4.8E-20 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CU254_RS32655 3a201c40204c570d0d6659871ca1acc5 642 Gene3D G3DSA:2.40.30.10 221 332 2.8E-25 T 28-03-2018 CU254_RS32655 3a201c40204c570d0d6659871ca1acc5 642 SUPERFAMILY SSF54980 334 420 1.01E-10 T 28-03-2018 IPR035647 EF-G domain III/V-like CU254_RS32655 3a201c40204c570d0d6659871ca1acc5 642 Pfam PF03144 Elongation factor Tu domain 2 251 321 1.1E-12 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CU254_RS32655 3a201c40204c570d0d6659871ca1acc5 642 SUPERFAMILY SSF52540 19 238 4.53E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS32655 3a201c40204c570d0d6659871ca1acc5 642 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 23 162 2.4E-24 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CU254_RS32655 3a201c40204c570d0d6659871ca1acc5 642 Gene3D G3DSA:3.40.50.300 3 220 1.2E-36 T 28-03-2018 CU254_RS32655 3a201c40204c570d0d6659871ca1acc5 642 SUPERFAMILY SSF54980 431 545 6.71E-28 T 28-03-2018 IPR035647 EF-G domain III/V-like CU254_RS39490 344bd527114d384fc98a9ef29fb6e7d7 664 SUPERFAMILY SSF56112 8 280 3.37E-80 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS39490 344bd527114d384fc98a9ef29fb6e7d7 664 SMART SM00220 11 274 6.4E-68 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CU254_RS39490 344bd527114d384fc98a9ef29fb6e7d7 664 Gene3D G3DSA:1.10.510.10 111 376 5.0E-52 T 28-03-2018 CU254_RS39490 344bd527114d384fc98a9ef29fb6e7d7 664 SUPERFAMILY SSF54184 572 635 3.4E-6 T 28-03-2018 CU254_RS39490 344bd527114d384fc98a9ef29fb6e7d7 664 Gene3D G3DSA:3.30.200.20 2 110 1.4E-25 T 28-03-2018 CU254_RS39490 344bd527114d384fc98a9ef29fb6e7d7 664 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 134 146 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CU254_RS39490 344bd527114d384fc98a9ef29fb6e7d7 664 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 17 40 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 CU254_RS39490 344bd527114d384fc98a9ef29fb6e7d7 664 Pfam PF00069 Protein kinase domain 11 265 8.0E-53 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CU254_RS39490 344bd527114d384fc98a9ef29fb6e7d7 664 SMART SM00740 503 567 1.4E-10 T 28-03-2018 IPR005543 PASTA domain CU254_RS39490 344bd527114d384fc98a9ef29fb6e7d7 664 SMART SM00740 434 502 5.1E-13 T 28-03-2018 IPR005543 PASTA domain CU254_RS39490 344bd527114d384fc98a9ef29fb6e7d7 664 SMART SM00740 353 433 1.3E-5 T 28-03-2018 IPR005543 PASTA domain CU254_RS39490 344bd527114d384fc98a9ef29fb6e7d7 664 SMART SM00740 568 636 2.8E-16 T 28-03-2018 IPR005543 PASTA domain CU254_RS39490 344bd527114d384fc98a9ef29fb6e7d7 664 Pfam PF03793 PASTA domain 439 501 4.9E-13 T 28-03-2018 IPR005543 PASTA domain CU254_RS39490 344bd527114d384fc98a9ef29fb6e7d7 664 Pfam PF03793 PASTA domain 572 634 4.0E-16 T 28-03-2018 IPR005543 PASTA domain CU254_RS39490 344bd527114d384fc98a9ef29fb6e7d7 664 Pfam PF03793 PASTA domain 508 567 6.3E-11 T 28-03-2018 IPR005543 PASTA domain CU254_RS39490 344bd527114d384fc98a9ef29fb6e7d7 664 Pfam PF03793 PASTA domain 359 433 4.4E-6 T 28-03-2018 IPR005543 PASTA domain CU254_RS06445 7d5a20a05f6063e059b650f3de48d394 795 Gene3D G3DSA:3.30.2080.10 641 788 2.6E-50 T 28-03-2018 CU254_RS06445 7d5a20a05f6063e059b650f3de48d394 795 SUPERFAMILY SSF48208 287 729 1.93E-19 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CU254_RS06445 7d5a20a05f6063e059b650f3de48d394 795 TIGRFAM TIGR01180 aman2_put: putative alpha-1,2-mannosidase 14 773 3.3E-156 T 28-03-2018 IPR005887 Alpha-1,2-mannosidase, putative CU254_RS06445 7d5a20a05f6063e059b650f3de48d394 795 Gene3D G3DSA:2.70.98.10 29 340 8.1E-82 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 CU254_RS06445 7d5a20a05f6063e059b650f3de48d394 795 Gene3D G3DSA:1.20.1050.60 363 459 2.3E-24 T 28-03-2018 CU254_RS06445 7d5a20a05f6063e059b650f3de48d394 795 Pfam PF07971 Glycosyl hydrolase family 92 259 773 7.4E-142 T 28-03-2018 IPR012939 Glycosyl hydrolase family 92 CU254_RS06445 7d5a20a05f6063e059b650f3de48d394 795 Gene3D G3DSA:1.20.1610.10 460 640 1.3E-42 T 28-03-2018 CU254_RS26985 52dd2a87fb891debfd8ec3e361e73fe6 416 Gene3D G3DSA:1.20.1250.20 205 400 6.9E-18 T 28-03-2018 CU254_RS26985 52dd2a87fb891debfd8ec3e361e73fe6 416 Pfam PF05977 Transmembrane secretion effector 8 396 6.6E-31 T 28-03-2018 IPR010290 Transmembrane secretion effector CU254_RS26985 52dd2a87fb891debfd8ec3e361e73fe6 416 Gene3D G3DSA:1.20.1250.20 6 204 5.2E-18 T 28-03-2018 CU254_RS26985 52dd2a87fb891debfd8ec3e361e73fe6 416 SUPERFAMILY SSF103473 1 395 4.97E-49 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS19020 bac02860f326066500f76a3995c30eb5 307 Gene3D G3DSA:1.10.1660.10 4 63 2.1E-24 T 28-03-2018 CU254_RS19020 bac02860f326066500f76a3995c30eb5 307 Pfam PF13411 MerR HTH family regulatory protein 8 76 4.1E-20 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS19020 bac02860f326066500f76a3995c30eb5 307 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 9 20 7.5E-10 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS19020 bac02860f326066500f76a3995c30eb5 307 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 20 33 7.5E-10 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS19020 bac02860f326066500f76a3995c30eb5 307 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 44 64 7.5E-10 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS19020 bac02860f326066500f76a3995c30eb5 307 SMART SM00422 8 77 3.3E-27 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS19020 bac02860f326066500f76a3995c30eb5 307 SUPERFAMILY SSF46955 8 110 3.66E-27 T 28-03-2018 IPR009061 Putative DNA-binding domain CU254_RS19020 bac02860f326066500f76a3995c30eb5 307 Gene3D G3DSA:1.10.1660.10 64 136 5.7E-7 T 28-03-2018 CU254_RS02760 f736deca4aef73d0b241ecead9d8efbb 339 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 9 335 8.4E-106 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CU254_RS02760 f736deca4aef73d0b241ecead9d8efbb 339 Pfam PF00579 tRNA synthetases class I (W and Y) 6 286 2.7E-82 T 28-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 CU254_RS02760 f736deca4aef73d0b241ecead9d8efbb 339 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 17 27 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CU254_RS02760 f736deca4aef73d0b241ecead9d8efbb 339 Gene3D G3DSA:1.10.240.10 198 318 9.4E-31 T 28-03-2018 CU254_RS02760 f736deca4aef73d0b241ecead9d8efbb 339 Gene3D G3DSA:3.40.50.620 2 197 1.7E-74 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS02760 f736deca4aef73d0b241ecead9d8efbb 339 SUPERFAMILY SSF52374 10 335 3.23E-96 T 28-03-2018 CU254_RS02760 f736deca4aef73d0b241ecead9d8efbb 339 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 8 336 41.423 T 28-03-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 CU254_RS02760 f736deca4aef73d0b241ecead9d8efbb 339 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 72 91 1.3E-26 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CU254_RS02760 f736deca4aef73d0b241ecead9d8efbb 339 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 22 38 1.3E-26 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CU254_RS02760 f736deca4aef73d0b241ecead9d8efbb 339 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 202 212 1.3E-26 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CU254_RS02760 f736deca4aef73d0b241ecead9d8efbb 339 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 149 170 1.3E-26 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CU254_RS11270 d91a665e9f207441cd585618b20dad14 598 SUPERFAMILY SSF55681 416 583 4.98E-99 T 28-03-2018 CU254_RS11270 d91a665e9f207441cd585618b20dad14 598 SUPERFAMILY SSF55681 113 292 4.98E-99 T 28-03-2018 CU254_RS11270 d91a665e9f207441cd585618b20dad14 598 PRINTS PR01042 Aspartyl-tRNA synthetase signature 518 532 4.7E-26 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CU254_RS11270 d91a665e9f207441cd585618b20dad14 598 PRINTS PR01042 Aspartyl-tRNA synthetase signature 191 203 4.7E-26 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CU254_RS11270 d91a665e9f207441cd585618b20dad14 598 PRINTS PR01042 Aspartyl-tRNA synthetase signature 208 221 4.7E-26 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CU254_RS11270 d91a665e9f207441cd585618b20dad14 598 PRINTS PR01042 Aspartyl-tRNA synthetase signature 474 490 4.7E-26 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CU254_RS11270 d91a665e9f207441cd585618b20dad14 598 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 2 584 32.244 T 28-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 CU254_RS11270 d91a665e9f207441cd585618b20dad14 598 Pfam PF01336 OB-fold nucleic acid binding domain 19 101 1.0E-16 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CU254_RS11270 d91a665e9f207441cd585618b20dad14 598 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 3 581 2.3E-212 T 28-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 CU254_RS11270 d91a665e9f207441cd585618b20dad14 598 SUPERFAMILY SSF55261 289 411 4.8E-35 T 28-03-2018 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 CU254_RS11270 d91a665e9f207441cd585618b20dad14 598 Gene3D G3DSA:3.30.930.10 132 586 2.5E-105 T 28-03-2018 CU254_RS11270 d91a665e9f207441cd585618b20dad14 598 Pfam PF02938 GAD domain 313 394 3.2E-14 T 28-03-2018 IPR029351 GAD domain Reactome: R-HSA-379726 CU254_RS11270 d91a665e9f207441cd585618b20dad14 598 Gene3D G3DSA:2.40.50.140 2 107 1.2E-26 T 28-03-2018 CU254_RS11270 d91a665e9f207441cd585618b20dad14 598 SUPERFAMILY SSF50249 2 104 1.01E-29 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CU254_RS11270 d91a665e9f207441cd585618b20dad14 598 Pfam PF00152 tRNA synthetases class II (D, K and N) 119 557 3.5E-100 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CU254_RS36680 49ec174fc4c4f33df4f8b78a1e1e3330 1030 Gene3D G3DSA:1.10.1200.10 963 1030 1.5E-16 T 28-03-2018 CU254_RS36680 49ec174fc4c4f33df4f8b78a1e1e3330 1030 SUPERFAMILY SSF47336 953 1026 1.22E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS36680 49ec174fc4c4f33df4f8b78a1e1e3330 1030 SMART SM00823 Phosphopantetheine attachment site 959 1027 2.2E-6 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS36680 49ec174fc4c4f33df4f8b78a1e1e3330 1030 Pfam PF00501 AMP-binding enzyme 470 852 7.0E-66 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS36680 49ec174fc4c4f33df4f8b78a1e1e3330 1030 Pfam PF00668 Condensation domain 13 430 2.8E-34 T 28-03-2018 IPR001242 Condensation domain CU254_RS36680 49ec174fc4c4f33df4f8b78a1e1e3330 1030 Gene3D G3DSA:3.40.50.980 605 756 5.3E-32 T 28-03-2018 CU254_RS36680 49ec174fc4c4f33df4f8b78a1e1e3330 1030 Pfam PF00550 Phosphopantetheine attachment site 961 1023 5.2E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS36680 49ec174fc4c4f33df4f8b78a1e1e3330 1030 SUPERFAMILY SSF56801 466 971 3.4E-116 T 28-03-2018 CU254_RS36680 49ec174fc4c4f33df4f8b78a1e1e3330 1030 Gene3D G3DSA:2.30.38.10 757 844 8.7E-19 T 28-03-2018 CU254_RS36680 49ec174fc4c4f33df4f8b78a1e1e3330 1030 SUPERFAMILY SSF52777 16 169 9.0E-20 T 28-03-2018 CU254_RS36680 49ec174fc4c4f33df4f8b78a1e1e3330 1030 Gene3D G3DSA:3.30.300.30 847 962 5.1E-28 T 28-03-2018 CU254_RS36680 49ec174fc4c4f33df4f8b78a1e1e3330 1030 Gene3D G3DSA:3.30.559.10 7 203 2.4E-20 T 28-03-2018 CU254_RS36680 49ec174fc4c4f33df4f8b78a1e1e3330 1030 SUPERFAMILY SSF52777 201 433 3.72E-34 T 28-03-2018 CU254_RS36680 49ec174fc4c4f33df4f8b78a1e1e3330 1030 Gene3D G3DSA:3.40.50.980 464 604 8.9E-29 T 28-03-2018 CU254_RS08890 422ef4d50b2dc924aa46eaa29ebad320 186 Pfam PF00510 Cytochrome c oxidase subunit III 3 184 5.7E-26 T 28-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CU254_RS08890 422ef4d50b2dc924aa46eaa29ebad320 186 Gene3D G3DSA:1.20.120.80 1 186 1.2E-52 T 28-03-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CU254_RS08890 422ef4d50b2dc924aa46eaa29ebad320 186 SUPERFAMILY SSF81452 3 185 1.96E-53 T 28-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CU254_RS10070 c1440112da9a51f6d0fcb2484c9cff88 379 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 13 295 2.7E-67 T 28-03-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CU254_RS10070 c1440112da9a51f6d0fcb2484c9cff88 379 Hamap MF_01609 Glutamate--cysteine ligase [gshA]. 1 379 100.785 T 28-03-2018 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CU254_RS10070 c1440112da9a51f6d0fcb2484c9cff88 379 TIGRFAM TIGR02050 gshA_cyan_rel: carboxylate-amine ligase, YbdK family 12 299 3.2E-102 T 28-03-2018 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CU254_RS10070 c1440112da9a51f6d0fcb2484c9cff88 379 SUPERFAMILY SSF55931 3 372 9.81E-111 T 28-03-2018 CU254_RS20860 6d3fcd9432f610ccc1acaf71b5548b84 275 Gene3D G3DSA:1.10.3720.10 8 263 6.9E-46 T 28-03-2018 CU254_RS20860 6d3fcd9432f610ccc1acaf71b5548b84 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 258 6.3E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS20860 6d3fcd9432f610ccc1acaf71b5548b84 275 SUPERFAMILY SSF161098 3 275 1.44E-67 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS13220 ed7e6d8952dbb615b95da6a5f384cad2 282 Gene3D G3DSA:3.20.10.10 119 276 2.7E-35 T 28-03-2018 CU254_RS13220 ed7e6d8952dbb615b95da6a5f384cad2 282 Pfam PF01063 Amino-transferase class IV 31 256 1.3E-43 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CU254_RS13220 ed7e6d8952dbb615b95da6a5f384cad2 282 SUPERFAMILY SSF56752 5 277 1.12E-56 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CU254_RS13220 ed7e6d8952dbb615b95da6a5f384cad2 282 Gene3D G3DSA:3.30.470.10 2 116 6.1E-28 T 28-03-2018 CU254_RS39710 47c644cd4a1f94ac1e9e9ec54a3d2ad7 138 SUPERFAMILY SSF69118 14 129 4.06E-34 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CU254_RS39710 47c644cd4a1f94ac1e9e9ec54a3d2ad7 138 Gene3D G3DSA:1.20.1290.10 14 138 3.7E-36 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CU254_RS39710 47c644cd4a1f94ac1e9e9ec54a3d2ad7 138 Pfam PF02627 Carboxymuconolactone decarboxylase family 42 127 1.7E-23 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CU254_RS21515 453af13d41b797d5b4ce48156a8df0dc 282 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 73 275 6.9E-59 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CU254_RS21515 453af13d41b797d5b4ce48156a8df0dc 282 Gene3D G3DSA:3.90.850.10 36 282 3.6E-71 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CU254_RS21515 453af13d41b797d5b4ce48156a8df0dc 282 SUPERFAMILY SSF56529 60 278 1.2E-67 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CU254_RS29390 3faade43a5e6c8d62ad357a0da0bf1b1 508 Gene3D G3DSA:1.20.1250.20 2 197 3.6E-29 T 28-03-2018 CU254_RS29390 3faade43a5e6c8d62ad357a0da0bf1b1 508 Pfam PF07690 Major Facilitator Superfamily 18 405 3.4E-43 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS29390 3faade43a5e6c8d62ad357a0da0bf1b1 508 PRINTS PR01035 Tetracycline resistance protein signature 136 158 4.9E-5 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CU254_RS29390 3faade43a5e6c8d62ad357a0da0bf1b1 508 PRINTS PR01035 Tetracycline resistance protein signature 23 39 4.9E-5 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CU254_RS29390 3faade43a5e6c8d62ad357a0da0bf1b1 508 PRINTS PR01035 Tetracycline resistance protein signature 301 321 4.9E-5 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CU254_RS29390 3faade43a5e6c8d62ad357a0da0bf1b1 508 PRINTS PR01035 Tetracycline resistance protein signature 53 72 4.9E-5 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CU254_RS29390 3faade43a5e6c8d62ad357a0da0bf1b1 508 Gene3D G3DSA:1.20.1250.20 255 503 1.3E-23 T 28-03-2018 CU254_RS29390 3faade43a5e6c8d62ad357a0da0bf1b1 508 SUPERFAMILY SSF103473 4 194 6.02E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS29390 3faade43a5e6c8d62ad357a0da0bf1b1 508 SUPERFAMILY SSF103473 467 495 6.02E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS29390 3faade43a5e6c8d62ad357a0da0bf1b1 508 SUPERFAMILY SSF103473 244 415 6.02E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS00520 dd567695c4f255a862aef282d4bff74a 65 Pfam PF12728 Helix-turn-helix domain 11 59 1.8E-11 T 28-03-2018 CU254_RS00520 dd567695c4f255a862aef282d4bff74a 65 SUPERFAMILY SSF46955 9 59 1.6E-11 T 28-03-2018 IPR009061 Putative DNA-binding domain CU254_RS00520 dd567695c4f255a862aef282d4bff74a 65 Gene3D G3DSA:1.10.10.10 12 63 2.3E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS20075 0a01a090a7e7fb75bb1646f7516e316e 121 Pfam PF10823 Protein of unknown function (DUF2568) 17 105 1.5E-19 T 28-03-2018 IPR021214 Protein of unknown function DUF2568 CU254_RS13330 2f1de83597e1ae01dcdfb63167e1ec06 200 SUPERFAMILY SSF109854 6 136 2.14E-9 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CU254_RS13330 2f1de83597e1ae01dcdfb63167e1ec06 200 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 15 132 4.6E-8 T 28-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CU254_RS13330 2f1de83597e1ae01dcdfb63167e1ec06 200 Gene3D G3DSA:1.20.120.450 3 138 1.4E-11 T 28-03-2018 CU254_RS19655 4b0f113aa11a06a58e8e270b2fd3a182 382 Pfam PF04542 Sigma-70 region 2 3 58 2.8E-5 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS19655 4b0f113aa11a06a58e8e270b2fd3a182 382 Gene3D G3DSA:1.25.40.10 249 380 0.024 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS19655 4b0f113aa11a06a58e8e270b2fd3a182 382 SUPERFAMILY SSF88659 79 138 6.54E-9 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS19655 4b0f113aa11a06a58e8e270b2fd3a182 382 Gene3D G3DSA:1.10.10.10 180 248 0.16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS19655 4b0f113aa11a06a58e8e270b2fd3a182 382 SUPERFAMILY SSF88946 4 63 1.92E-6 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS19655 4b0f113aa11a06a58e8e270b2fd3a182 382 Gene3D G3DSA:1.10.10.10 57 139 6.4E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS19655 4b0f113aa11a06a58e8e270b2fd3a182 382 Gene3D G3DSA:1.10.1740.10 1 56 1.3E-9 T 28-03-2018 CU254_RS02815 04ee28a0bc7265635823b9cf950298db 149 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 28 131 8.5E-29 T 28-03-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CU254_RS02815 04ee28a0bc7265635823b9cf950298db 149 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 28 130 7.5E-24 T 28-03-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CU254_RS02815 04ee28a0bc7265635823b9cf950298db 149 SUPERFAMILY SSF81343 26 136 6.7E-28 T 28-03-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CU254_RS02815 04ee28a0bc7265635823b9cf950298db 149 Gene3D G3DSA:1.20.1300.10 16 138 1.2E-27 T 28-03-2018 CU254_RS28750 ee9e400e3b6238e092adc30865aaf06c 123 SUPERFAMILY SSF46894 57 123 1.94E-12 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS28750 ee9e400e3b6238e092adc30865aaf06c 123 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 63 77 2.6E-5 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS28750 ee9e400e3b6238e092adc30865aaf06c 123 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 77 93 2.6E-5 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS28750 ee9e400e3b6238e092adc30865aaf06c 123 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 93 105 2.6E-5 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS28750 ee9e400e3b6238e092adc30865aaf06c 123 Gene3D G3DSA:1.10.10.10 17 123 3.4E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS28750 ee9e400e3b6238e092adc30865aaf06c 123 Pfam PF00196 Bacterial regulatory proteins, luxR family 71 115 1.3E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS28750 ee9e400e3b6238e092adc30865aaf06c 123 SMART SM00421 60 117 7.3E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS41305 da78d8bac146d0993a6069f4b3b08e37 431 PRINTS PR00385 P450 superfamily signature 372 383 1.3E-5 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS41305 da78d8bac146d0993a6069f4b3b08e37 431 PRINTS PR00385 P450 superfamily signature 259 276 1.3E-5 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS41305 da78d8bac146d0993a6069f4b3b08e37 431 PRINTS PR00385 P450 superfamily signature 295 306 1.3E-5 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS41305 da78d8bac146d0993a6069f4b3b08e37 431 PRINTS PR00385 P450 superfamily signature 363 372 1.3E-5 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS41305 da78d8bac146d0993a6069f4b3b08e37 431 Gene3D G3DSA:1.10.630.10 15 424 3.2E-76 T 28-03-2018 CU254_RS41305 da78d8bac146d0993a6069f4b3b08e37 431 SUPERFAMILY SSF48264 20 423 2.1E-88 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS41305 da78d8bac146d0993a6069f4b3b08e37 431 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 365 374 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CU254_RS41305 da78d8bac146d0993a6069f4b3b08e37 431 PRINTS PR00359 B-class P450 signature 97 108 7.7E-26 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS41305 da78d8bac146d0993a6069f4b3b08e37 431 PRINTS PR00359 B-class P450 signature 313 340 7.7E-26 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS41305 da78d8bac146d0993a6069f4b3b08e37 431 PRINTS PR00359 B-class P450 signature 372 383 7.7E-26 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS41305 da78d8bac146d0993a6069f4b3b08e37 431 PRINTS PR00359 B-class P450 signature 363 372 7.7E-26 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS41305 da78d8bac146d0993a6069f4b3b08e37 431 PRINTS PR00359 B-class P450 signature 147 163 7.7E-26 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS41305 da78d8bac146d0993a6069f4b3b08e37 431 PRINTS PR00359 B-class P450 signature 164 179 7.7E-26 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS41305 da78d8bac146d0993a6069f4b3b08e37 431 PRINTS PR00359 B-class P450 signature 295 306 7.7E-26 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS41305 da78d8bac146d0993a6069f4b3b08e37 431 Pfam PF00067 Cytochrome P450 184 284 1.8E-5 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS41305 da78d8bac146d0993a6069f4b3b08e37 431 Pfam PF00067 Cytochrome P450 295 412 4.2E-15 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS31185 f045d5285756c379c08747752fc080d6 182 Gene3D G3DSA:3.40.50.850 1 182 1.0E-40 T 28-03-2018 CU254_RS31185 f045d5285756c379c08747752fc080d6 182 SUPERFAMILY SSF52499 2 181 2.49E-39 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CU254_RS31185 f045d5285756c379c08747752fc080d6 182 Pfam PF00857 Isochorismatase family 3 147 3.7E-27 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CU254_RS02870 654f12f26c1e3b31156490e8d07695af 234 Pfam PF00106 short chain dehydrogenase 6 181 1.9E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS02870 654f12f26c1e3b31156490e8d07695af 234 SUPERFAMILY SSF51735 4 222 2.54E-25 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS02870 654f12f26c1e3b31156490e8d07695af 234 Gene3D G3DSA:3.40.50.720 2 231 8.5E-23 T 28-03-2018 CU254_RS31850 4f0b9d742e73f898619d1412ae490816 139 SUPERFAMILY SSF54637 9 134 9.71E-25 T 28-03-2018 IPR029069 HotDog domain CU254_RS31850 4f0b9d742e73f898619d1412ae490816 139 Pfam PF03061 Thioesterase superfamily 45 116 3.7E-11 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CU254_RS31850 4f0b9d742e73f898619d1412ae490816 139 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 17 116 6.4E-12 T 28-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 CU254_RS31850 4f0b9d742e73f898619d1412ae490816 139 Gene3D G3DSA:3.10.129.10 2 139 3.0E-26 T 28-03-2018 CU254_RS13710 f1ffb5d76abc8ffc20ca3b184f80bf3b 368 PRINTS PR00385 P450 superfamily signature 315 326 3.5E-6 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS13710 f1ffb5d76abc8ffc20ca3b184f80bf3b 368 PRINTS PR00385 P450 superfamily signature 306 315 3.5E-6 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS13710 f1ffb5d76abc8ffc20ca3b184f80bf3b 368 PRINTS PR00385 P450 superfamily signature 203 220 3.5E-6 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS13710 f1ffb5d76abc8ffc20ca3b184f80bf3b 368 PRINTS PR00385 P450 superfamily signature 238 249 3.5E-6 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS13710 f1ffb5d76abc8ffc20ca3b184f80bf3b 368 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 308 317 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CU254_RS13710 f1ffb5d76abc8ffc20ca3b184f80bf3b 368 SUPERFAMILY SSF48264 3 367 2.49E-87 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS13710 f1ffb5d76abc8ffc20ca3b184f80bf3b 368 PRINTS PR00359 B-class P450 signature 315 326 5.2E-39 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS13710 f1ffb5d76abc8ffc20ca3b184f80bf3b 368 PRINTS PR00359 B-class P450 signature 256 283 5.2E-39 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS13710 f1ffb5d76abc8ffc20ca3b184f80bf3b 368 PRINTS PR00359 B-class P450 signature 55 66 5.2E-39 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS13710 f1ffb5d76abc8ffc20ca3b184f80bf3b 368 PRINTS PR00359 B-class P450 signature 102 118 5.2E-39 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS13710 f1ffb5d76abc8ffc20ca3b184f80bf3b 368 PRINTS PR00359 B-class P450 signature 156 178 5.2E-39 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS13710 f1ffb5d76abc8ffc20ca3b184f80bf3b 368 PRINTS PR00359 B-class P450 signature 119 134 5.2E-39 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS13710 f1ffb5d76abc8ffc20ca3b184f80bf3b 368 PRINTS PR00359 B-class P450 signature 306 315 5.2E-39 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS13710 f1ffb5d76abc8ffc20ca3b184f80bf3b 368 PRINTS PR00359 B-class P450 signature 238 249 5.2E-39 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS13710 f1ffb5d76abc8ffc20ca3b184f80bf3b 368 Gene3D G3DSA:1.10.630.10 1 368 1.8E-72 T 28-03-2018 CU254_RS13710 f1ffb5d76abc8ffc20ca3b184f80bf3b 368 Pfam PF00067 Cytochrome P450 239 336 4.5E-14 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS13710 f1ffb5d76abc8ffc20ca3b184f80bf3b 368 Pfam PF00067 Cytochrome P450 151 224 5.8E-6 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS13920 0c36184b6042cee3a86622ff076e6f41 343 Gene3D G3DSA:1.10.600.10 2 343 1.9E-90 T 28-03-2018 IPR008949 Isoprenoid synthase domain CU254_RS13920 0c36184b6042cee3a86622ff076e6f41 343 SUPERFAMILY SSF48576 59 341 2.34E-75 T 28-03-2018 IPR008949 Isoprenoid synthase domain CU254_RS13920 0c36184b6042cee3a86622ff076e6f41 343 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 226 238 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site CU254_RS13920 0c36184b6042cee3a86622ff076e6f41 343 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 101 115 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site CU254_RS13920 0c36184b6042cee3a86622ff076e6f41 343 Pfam PF00348 Polyprenyl synthetase 62 296 7.6E-52 T 28-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 CU254_RS05190 4a3672c549d8a0f492a86854fe24ab69 531 Gene3D G3DSA:2.80.10.50 449 483 7.6E-9 T 28-03-2018 CU254_RS05190 4a3672c549d8a0f492a86854fe24ab69 531 Gene3D G3DSA:2.80.10.50 484 530 3.5E-12 T 28-03-2018 CU254_RS05190 4a3672c549d8a0f492a86854fe24ab69 531 SMART SM00458 402 530 3.3E-21 T 28-03-2018 IPR000772 Ricin B, lectin domain CU254_RS05190 4a3672c549d8a0f492a86854fe24ab69 531 Gene3D G3DSA:4.10.1090.10 393 448 2.5E-8 T 28-03-2018 CU254_RS05190 4a3672c549d8a0f492a86854fe24ab69 531 SUPERFAMILY SSF50939 37 272 2.62E-17 T 28-03-2018 IPR011040 Sialidases KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 CU254_RS05190 4a3672c549d8a0f492a86854fe24ab69 531 Gene3D G3DSA:2.120.10.10 13 392 2.1E-46 T 28-03-2018 CU254_RS05190 4a3672c549d8a0f492a86854fe24ab69 531 Pfam PF00652 Ricin-type beta-trefoil lectin domain 404 527 6.4E-25 T 28-03-2018 IPR000772 Ricin B, lectin domain CU254_RS05190 4a3672c549d8a0f492a86854fe24ab69 531 SUPERFAMILY SSF50370 403 529 3.65E-32 T 28-03-2018 IPR000772 Ricin B, lectin domain CU254_RS28335 57b10e9f281a3992656683bb25e03d82 74 Pfam PF13459 4Fe-4S single cluster domain 8 63 6.4E-10 T 28-03-2018 CU254_RS28335 57b10e9f281a3992656683bb25e03d82 74 Gene3D G3DSA:3.30.70.20 5 66 1.2E-5 T 28-03-2018 CU254_RS28335 57b10e9f281a3992656683bb25e03d82 74 SUPERFAMILY SSF54862 7 64 1.9E-8 T 28-03-2018 CU254_RS28335 57b10e9f281a3992656683bb25e03d82 74 PRINTS PR00352 3Fe-4S ferredoxin signature 49 61 2.9E-6 T 28-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CU254_RS28335 57b10e9f281a3992656683bb25e03d82 74 PRINTS PR00352 3Fe-4S ferredoxin signature 10 21 2.9E-6 T 28-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CU254_RS28335 57b10e9f281a3992656683bb25e03d82 74 PRINTS PR00352 3Fe-4S ferredoxin signature 21 31 2.9E-6 T 28-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CU254_RS06280 9e79eb51c3ac00767fe3038d35667608 313 SUPERFAMILY SSF47240 33 275 5.68E-83 T 28-03-2018 IPR009078 Ferritin-like superfamily CU254_RS06280 9e79eb51c3ac00767fe3038d35667608 313 TIGRFAM TIGR02156 PA_CoA_Oxy1: phenylacetate-CoA oxygenase, PaaG subunit 13 301 1.7E-156 T 28-03-2018 IPR011881 1,2-phenylacetyl-CoA epoxidase, subunit A GO:0010124|GO:0097266 KEGG: 00360+1.14.13.14+1.14.13.149|KEGG: 00940+1.14.13.14|MetaCyc: PWY-5176 CU254_RS06280 9e79eb51c3ac00767fe3038d35667608 313 Pfam PF05138 Phenylacetic acid catabolic protein 23 297 2.3E-102 T 28-03-2018 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 CU254_RS06280 9e79eb51c3ac00767fe3038d35667608 313 Gene3D G3DSA:1.10.620.20 5 292 1.6E-83 T 28-03-2018 CU254_RS17935 72d388d91c4469beaa2e21fe70665b91 449 SUPERFAMILY SSF109854 17 152 4.88E-20 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CU254_RS17935 72d388d91c4469beaa2e21fe70665b91 449 Hamap MF_02035 Hercynine oxygenase [egtB]. 1 443 52.431 T 28-03-2018 IPR032890 Hercynine oxygenase, Actinobacteria GO:0016491|GO:0052699 CU254_RS17935 72d388d91c4469beaa2e21fe70665b91 449 Gene3D G3DSA:1.20.120.450 3 166 3.1E-19 T 28-03-2018 CU254_RS17935 72d388d91c4469beaa2e21fe70665b91 449 TIGRFAM TIGR03440 egtB_TIGR03440: ergothioneine biosynthesis protein EgtB 23 440 4.5E-135 T 28-03-2018 IPR017806 Ergothioneine biosynthesis protein EgtB GO:0052699 CU254_RS17935 72d388d91c4469beaa2e21fe70665b91 449 Pfam PF03781 Sulfatase-modifying factor enzyme 1 182 441 1.8E-66 T 28-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 CU254_RS17935 72d388d91c4469beaa2e21fe70665b91 449 Pfam PF12867 DinB superfamily 25 156 5.7E-26 T 28-03-2018 IPR024775 DinB-like domain CU254_RS17935 72d388d91c4469beaa2e21fe70665b91 449 SUPERFAMILY SSF56436 185 443 5.27E-76 T 28-03-2018 IPR016187 C-type lectin fold CU254_RS17935 72d388d91c4469beaa2e21fe70665b91 449 Gene3D G3DSA:3.90.1580.10 174 449 8.6E-72 T 28-03-2018 CU254_RS07405 da9201fe096c5d739d05add626086da2 334 Pfam PF04055 Radical SAM superfamily 81 231 4.7E-11 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CU254_RS07405 da9201fe096c5d739d05add626086da2 334 SMART SM00729 71 277 1.1E-14 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CU254_RS07405 da9201fe096c5d739d05add626086da2 334 PIRSF PIRSF005963 1 318 2.0E-119 T 28-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CU254_RS07405 da9201fe096c5d739d05add626086da2 334 SUPERFAMILY SSF102114 35 296 4.19E-59 T 28-03-2018 CU254_RS07405 da9201fe096c5d739d05add626086da2 334 Gene3D G3DSA:3.20.20.70 29 321 4.7E-21 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS07405 da9201fe096c5d739d05add626086da2 334 Hamap MF_00206 Lipoyl synthase [lipA]. 1 307 138.692 T 28-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CU254_RS07405 da9201fe096c5d739d05add626086da2 334 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 24 60 5.8E-8 T 28-03-2018 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CU254_RS07405 da9201fe096c5d739d05add626086da2 334 TIGRFAM TIGR00510 lipA: lipoyl synthase 18 303 2.7E-98 T 28-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CU254_RS10880 7c97754ca5cf841f635628fb94e334ad 167 Pfam PF00692 dUTPase 18 145 4.3E-31 T 28-03-2018 IPR029054 dUTPase-like CU254_RS10880 7c97754ca5cf841f635628fb94e334ad 167 TIGRFAM TIGR00576 dut: dUTP diphosphatase 7 145 4.5E-49 T 28-03-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|Reactome: R-HSA-499943 CU254_RS10880 7c97754ca5cf841f635628fb94e334ad 167 SUPERFAMILY SSF51283 2 145 1.96E-46 T 28-03-2018 IPR029054 dUTPase-like CU254_RS10880 7c97754ca5cf841f635628fb94e334ad 167 Gene3D G3DSA:2.70.40.10 110 145 1.5E-13 T 28-03-2018 CU254_RS10880 7c97754ca5cf841f635628fb94e334ad 167 Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 4 146 31.396 T 28-03-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|Reactome: R-HSA-499943 CU254_RS10880 7c97754ca5cf841f635628fb94e334ad 167 Gene3D G3DSA:2.70.40.10 1 109 9.3E-41 T 28-03-2018 CU254_RS00815 742bf65b39b0efd65c9fd8534d276bff 342 SUPERFAMILY SSF53686 14 334 1.19E-69 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CU254_RS00815 742bf65b39b0efd65c9fd8534d276bff 342 Gene3D G3DSA:3.40.50.1100 157 338 1.6E-22 T 28-03-2018 CU254_RS00815 742bf65b39b0efd65c9fd8534d276bff 342 Gene3D G3DSA:3.40.50.1100 56 156 4.7E-29 T 28-03-2018 CU254_RS00815 742bf65b39b0efd65c9fd8534d276bff 342 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 19 324 9.5E-48 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CU254_RS00815 742bf65b39b0efd65c9fd8534d276bff 342 PIRSF PIRSF006278 1 342 3.2E-81 T 28-03-2018 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase CU254_RS42095 12c3d2f4a7558e016d9524af7838aec8 176 Gene3D G3DSA:3.10.129.10 1 154 6.0E-33 T 28-03-2018 CU254_RS42095 12c3d2f4a7558e016d9524af7838aec8 176 SUPERFAMILY SSF54637 6 155 3.35E-47 T 28-03-2018 IPR029069 HotDog domain CU254_RS42095 12c3d2f4a7558e016d9524af7838aec8 176 Pfam PF01575 MaoC like domain 17 123 1.4E-16 T 28-03-2018 IPR002539 MaoC-like domain CU254_RS41050 4a681ac7a4cea063ac82d942706ab29f 274 Pfam PF00459 Inositol monophosphatase family 28 258 2.0E-46 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CU254_RS41050 4a681ac7a4cea063ac82d942706ab29f 274 PRINTS PR00377 Inositol monophosphatase superfamily signature 38 58 1.5E-33 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CU254_RS41050 4a681ac7a4cea063ac82d942706ab29f 274 PRINTS PR00377 Inositol monophosphatase superfamily signature 177 198 1.5E-33 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CU254_RS41050 4a681ac7a4cea063ac82d942706ab29f 274 PRINTS PR00377 Inositol monophosphatase superfamily signature 208 232 1.5E-33 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CU254_RS41050 4a681ac7a4cea063ac82d942706ab29f 274 PRINTS PR00377 Inositol monophosphatase superfamily signature 78 94 1.5E-33 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CU254_RS41050 4a681ac7a4cea063ac82d942706ab29f 274 PRINTS PR00377 Inositol monophosphatase superfamily signature 127 150 1.5E-33 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CU254_RS41050 4a681ac7a4cea063ac82d942706ab29f 274 PRINTS PR00377 Inositol monophosphatase superfamily signature 60 76 1.5E-33 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CU254_RS41050 4a681ac7a4cea063ac82d942706ab29f 274 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 211 225 - T 28-03-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 CU254_RS41050 4a681ac7a4cea063ac82d942706ab29f 274 Gene3D G3DSA:3.30.540.10 2 142 1.9E-34 T 28-03-2018 CU254_RS41050 4a681ac7a4cea063ac82d942706ab29f 274 Gene3D G3DSA:3.40.190.80 143 266 6.4E-22 T 28-03-2018 CU254_RS41050 4a681ac7a4cea063ac82d942706ab29f 274 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 78 91 - T 28-03-2018 IPR020583 Inositol monophosphatase, metal-binding site CU254_RS41050 4a681ac7a4cea063ac82d942706ab29f 274 SUPERFAMILY SSF56655 8 258 1.03E-58 T 28-03-2018 CU254_RS24910 371923da3d97e72ee6f6b0f900b48f62 438 Gene3D G3DSA:1.20.1250.20 209 418 3.7E-13 T 28-03-2018 CU254_RS24910 371923da3d97e72ee6f6b0f900b48f62 438 Gene3D G3DSA:1.20.1250.20 8 204 3.2E-28 T 28-03-2018 CU254_RS24910 371923da3d97e72ee6f6b0f900b48f62 438 SUPERFAMILY SSF103473 8 406 9.94E-55 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS24910 371923da3d97e72ee6f6b0f900b48f62 438 Pfam PF07690 Major Facilitator Superfamily 21 327 1.4E-26 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS26470 6923534f71c7c9e9e2b79d77062f4957 341 SUPERFAMILY SSF55781 73 340 2.94E-57 T 28-03-2018 IPR029016 GAF domain-like CU254_RS26470 6923534f71c7c9e9e2b79d77062f4957 341 Gene3D G3DSA:3.30.450.40 189 341 1.9E-37 T 28-03-2018 IPR029016 GAF domain-like CU254_RS26470 6923534f71c7c9e9e2b79d77062f4957 341 Gene3D G3DSA:1.10.10.10 1 87 1.3E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS26470 6923534f71c7c9e9e2b79d77062f4957 341 Pfam PF01628 HrcA protein C terminal domain 105 324 2.5E-60 T 28-03-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 CU254_RS26470 6923534f71c7c9e9e2b79d77062f4957 341 PIRSF PIRSF005485 1 341 3.5E-102 T 28-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CU254_RS26470 6923534f71c7c9e9e2b79d77062f4957 341 SUPERFAMILY SSF46785 4 84 1.34E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS26470 6923534f71c7c9e9e2b79d77062f4957 341 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 3 331 27.577 T 28-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CU254_RS26470 6923534f71c7c9e9e2b79d77062f4957 341 Pfam PF08220 DeoR-like helix-turn-helix domain 17 64 8.2E-5 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CU254_RS26470 6923534f71c7c9e9e2b79d77062f4957 341 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 5 337 1.5E-93 T 28-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CU254_RS02525 0fa0ef423d3e1fa5dd77172452454048 300 SUPERFAMILY SSF53850 89 298 1.49E-40 T 28-03-2018 CU254_RS02525 0fa0ef423d3e1fa5dd77172452454048 300 Gene3D G3DSA:3.40.190.10 180 270 2.3E-27 T 28-03-2018 CU254_RS02525 0fa0ef423d3e1fa5dd77172452454048 300 Pfam PF03466 LysR substrate binding domain 88 295 2.3E-43 T 28-03-2018 IPR005119 LysR, substrate-binding CU254_RS02525 0fa0ef423d3e1fa5dd77172452454048 300 SUPERFAMILY SSF46785 1 110 9.19E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS02525 0fa0ef423d3e1fa5dd77172452454048 300 Gene3D G3DSA:1.10.10.10 1 87 1.7E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS02525 0fa0ef423d3e1fa5dd77172452454048 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 4.4E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS02525 0fa0ef423d3e1fa5dd77172452454048 300 Gene3D G3DSA:3.40.190.10 89 179 4.1E-23 T 28-03-2018 CU254_RS32265 9f55481473d66f3a8fb5d6fe71a66374 234 SUPERFAMILY SSF161098 20 203 1.15E-31 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS32265 9f55481473d66f3a8fb5d6fe71a66374 234 Gene3D G3DSA:1.10.3720.10 2 217 6.5E-26 T 28-03-2018 CU254_RS32265 9f55481473d66f3a8fb5d6fe71a66374 234 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 43 214 8.8E-23 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS10325 f79d2846c0250b9ad7c7d6d8bf576953 268 Pfam PF00106 short chain dehydrogenase 1 177 9.5E-45 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS10325 f79d2846c0250b9ad7c7d6d8bf576953 268 Gene3D G3DSA:3.40.50.720 1 266 6.0E-55 T 28-03-2018 CU254_RS10325 f79d2846c0250b9ad7c7d6d8bf576953 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 157 2.6E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS10325 f79d2846c0250b9ad7c7d6d8bf576953 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 65 76 2.6E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS10325 f79d2846c0250b9ad7c7d6d8bf576953 268 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 118 126 2.6E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS10325 f79d2846c0250b9ad7c7d6d8bf576953 268 SUPERFAMILY SSF51735 1 230 2.32E-56 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS10325 f79d2846c0250b9ad7c7d6d8bf576953 268 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 125 153 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS10325 f79d2846c0250b9ad7c7d6d8bf576953 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 176 8.9E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS10325 f79d2846c0250b9ad7c7d6d8bf576953 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 112 128 8.9E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS10325 f79d2846c0250b9ad7c7d6d8bf576953 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 65 76 8.9E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS10325 f79d2846c0250b9ad7c7d6d8bf576953 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 157 8.9E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23930 5f6f66200d124f7b92158592d973193f 384 Gene3D G3DSA:1.20.140.10 224 381 3.5E-38 T 28-03-2018 CU254_RS23930 5f6f66200d124f7b92158592d973193f 384 SUPERFAMILY SSF56645 3 242 3.01E-65 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS23930 5f6f66200d124f7b92158592d973193f 384 Gene3D G3DSA:1.10.540.10 1 117 8.4E-23 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS23930 5f6f66200d124f7b92158592d973193f 384 SUPERFAMILY SSF47203 231 374 2.58E-20 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS23930 5f6f66200d124f7b92158592d973193f 384 Gene3D G3DSA:2.40.110.10 118 223 3.3E-31 T 28-03-2018 CU254_RS23930 5f6f66200d124f7b92158592d973193f 384 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 372 1.0E-19 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS23930 5f6f66200d124f7b92158592d973193f 384 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 124 219 4.0E-20 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CU254_RS23930 5f6f66200d124f7b92158592d973193f 384 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 118 5.7E-17 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS29730 66651eec91fa97870e521b24fc1ad939 118 SUPERFAMILY SSF46785 5 85 7.78E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS29730 66651eec91fa97870e521b24fc1ad939 118 Gene3D G3DSA:1.10.10.10 1 79 1.4E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS29730 66651eec91fa97870e521b24fc1ad939 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 37 52 1.5E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS29730 66651eec91fa97870e521b24fc1ad939 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 5 20 1.5E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS29730 66651eec91fa97870e521b24fc1ad939 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 67 1.5E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS29730 66651eec91fa97870e521b24fc1ad939 118 Pfam PF12840 Helix-turn-helix domain 3 61 4.9E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS29730 66651eec91fa97870e521b24fc1ad939 118 Gene3D G3DSA:1.10.10.10 80 112 0.092 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS29730 66651eec91fa97870e521b24fc1ad939 118 SMART SM00418 3 81 1.3E-21 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS16160 0be79080f2910408fcd7ce590fe0dd28 454 Gene3D G3DSA:3.50.50.60 3 422 5.6E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS16160 0be79080f2910408fcd7ce590fe0dd28 454 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 4.5E-19 T 28-03-2018 CU254_RS16160 0be79080f2910408fcd7ce590fe0dd28 454 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 297 312 4.5E-19 T 28-03-2018 CU254_RS16160 0be79080f2910408fcd7ce590fe0dd28 454 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 312 328 4.5E-19 T 28-03-2018 CU254_RS16160 0be79080f2910408fcd7ce590fe0dd28 454 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 158 173 4.5E-19 T 28-03-2018 CU254_RS16160 0be79080f2910408fcd7ce590fe0dd28 454 SUPERFAMILY SSF51905 284 394 5.54E-57 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS16160 0be79080f2910408fcd7ce590fe0dd28 454 SUPERFAMILY SSF51905 5 179 5.54E-57 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS16160 0be79080f2910408fcd7ce590fe0dd28 454 Pfam PF01494 FAD binding domain 6 334 1.3E-25 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CU254_RS12130 3ceb570002113b24c6ca25b1b1034044 373 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 336 350 2.4E-37 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CU254_RS12130 3ceb570002113b24c6ca25b1b1034044 373 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 312 335 2.4E-37 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CU254_RS12130 3ceb570002113b24c6ca25b1b1034044 373 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 211 225 2.4E-37 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CU254_RS12130 3ceb570002113b24c6ca25b1b1034044 373 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 272 292 2.4E-37 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CU254_RS12130 3ceb570002113b24c6ca25b1b1034044 373 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 293 310 2.4E-37 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CU254_RS12130 3ceb570002113b24c6ca25b1b1034044 373 Gene3D G3DSA:3.30.300.50 29 107 8.1E-23 T 28-03-2018 IPR035070 Streptogrisin prodomain CU254_RS12130 3ceb570002113b24c6ca25b1b1034044 373 SUPERFAMILY SSF50494 194 364 3.43E-32 T 28-03-2018 IPR009003 Peptidase S1, PA clan CU254_RS12130 3ceb570002113b24c6ca25b1b1034044 373 Gene3D G3DSA:2.40.10.10 188 267 1.1E-18 T 28-03-2018 CU254_RS12130 3ceb570002113b24c6ca25b1b1034044 373 Pfam PF02983 Alpha-lytic protease prodomain 111 168 6.5E-11 T 28-03-2018 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 CU254_RS12130 3ceb570002113b24c6ca25b1b1034044 373 Pfam PF00089 Trypsin 271 363 8.5E-7 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CU254_RS12130 3ceb570002113b24c6ca25b1b1034044 373 Gene3D G3DSA:3.30.300.50 108 179 4.3E-14 T 28-03-2018 IPR035070 Streptogrisin prodomain CU254_RS12130 3ceb570002113b24c6ca25b1b1034044 373 Gene3D G3DSA:2.40.10.10 268 358 5.5E-17 T 28-03-2018 CU254_RS12130 3ceb570002113b24c6ca25b1b1034044 373 PIRSF PIRSF001134 1 373 7.8E-117 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CU254_RS32105 fd53d7c7a2930ca5f18b98e96f4dbe82 120 Pfam PF01638 HxlR-like helix-turn-helix 20 107 1.6E-26 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type CU254_RS32105 fd53d7c7a2930ca5f18b98e96f4dbe82 120 Gene3D G3DSA:1.10.10.10 18 119 6.0E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS32105 fd53d7c7a2930ca5f18b98e96f4dbe82 120 SUPERFAMILY SSF46785 10 112 4.05E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS11475 718fe324970b4bcfac775b4927338cd3 428 Hamap MF_00220_B Dihydroorotase [pyrC]. 2 425 41.878 T 28-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CU254_RS11475 718fe324970b4bcfac775b4927338cd3 428 SUPERFAMILY SSF51338 367 427 1.36E-25 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS11475 718fe324970b4bcfac775b4927338cd3 428 SUPERFAMILY SSF51338 3 50 1.36E-25 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS11475 718fe324970b4bcfac775b4927338cd3 428 Gene3D G3DSA:2.30.40.10 1 65 9.3E-21 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS11475 718fe324970b4bcfac775b4927338cd3 428 SUPERFAMILY SSF51556 51 366 2.58E-91 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS11475 718fe324970b4bcfac775b4927338cd3 428 Gene3D G3DSA:3.20.20.140 66 388 1.8E-90 T 28-03-2018 CU254_RS11475 718fe324970b4bcfac775b4927338cd3 428 ProSitePatterns PS00483 Dihydroorotase signature 2. 301 312 - T 28-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CU254_RS11475 718fe324970b4bcfac775b4927338cd3 428 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 15 424 1.0E-140 T 28-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CU254_RS11475 718fe324970b4bcfac775b4927338cd3 428 Pfam PF01979 Amidohydrolase family 47 420 5.6E-18 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CU254_RS25730 de075eea2b001963c6b9f15e5f6482dd 1052 Gene3D G3DSA:1.10.10.10 10 102 1.7E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS25730 de075eea2b001963c6b9f15e5f6482dd 1052 SUPERFAMILY SSF48452 97 261 6.83E-34 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS25730 de075eea2b001963c6b9f15e5f6482dd 1052 Gene3D G3DSA:1.25.40.10 103 257 2.6E-22 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS25730 de075eea2b001963c6b9f15e5f6482dd 1052 SUPERFAMILY SSF46894 3 94 1.22E-13 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS25730 de075eea2b001963c6b9f15e5f6482dd 1052 SUPERFAMILY SSF52540 256 522 3.34E-24 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS25730 de075eea2b001963c6b9f15e5f6482dd 1052 SMART SM00862 16 94 1.4E-9 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS25730 de075eea2b001963c6b9f15e5f6482dd 1052 Pfam PF03704 Bacterial transcriptional activator domain 101 243 2.2E-42 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CU254_RS25730 de075eea2b001963c6b9f15e5f6482dd 1052 Gene3D G3DSA:1.25.40.10 622 872 3.3E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS25730 de075eea2b001963c6b9f15e5f6482dd 1052 Gene3D G3DSA:1.25.40.10 873 988 6.3E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS25730 de075eea2b001963c6b9f15e5f6482dd 1052 Gene3D G3DSA:3.40.50.300 258 409 1.0E-12 T 28-03-2018 CU254_RS25730 de075eea2b001963c6b9f15e5f6482dd 1052 SUPERFAMILY SSF48452 712 831 3.45E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS25730 de075eea2b001963c6b9f15e5f6482dd 1052 SUPERFAMILY SSF48452 840 985 1.9E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS25730 de075eea2b001963c6b9f15e5f6482dd 1052 Pfam PF00931 NB-ARC domain 274 534 4.7E-9 T 28-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 CU254_RS25730 de075eea2b001963c6b9f15e5f6482dd 1052 SMART SM01043 101 243 5.2E-52 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CU254_RS25730 de075eea2b001963c6b9f15e5f6482dd 1052 Pfam PF00486 Transcriptional regulatory protein, C terminal 23 78 5.1E-9 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS25730 de075eea2b001963c6b9f15e5f6482dd 1052 PRINTS PR00364 Disease resistance protein signature 364 378 8.9E-8 T 28-03-2018 CU254_RS25730 de075eea2b001963c6b9f15e5f6482dd 1052 PRINTS PR00364 Disease resistance protein signature 282 297 8.9E-8 T 28-03-2018 CU254_RS25730 de075eea2b001963c6b9f15e5f6482dd 1052 PRINTS PR00364 Disease resistance protein signature 456 470 8.9E-8 T 28-03-2018 CU254_RS25805 382caaa4ad362370e48876e224ad97d9 112 ProSitePatterns PS00234 Gas vesicles protein GVPa signature 1. 26 40 - T 28-03-2018 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 CU254_RS25805 382caaa4ad362370e48876e224ad97d9 112 Pfam PF00741 Gas vesicle protein 25 63 3.2E-16 T 28-03-2018 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 CU254_RS36890 a9f73059bd244a23a40cc5e55623c6c5 350 ProSitePatterns PS01173 Lipolytic enzymes "G-D-X-G" family, putative histidine active site. 116 132 - T 28-03-2018 IPR002168 Lipase, GDXG, putative histidine active site GO:0008152|GO:0016787 Reactome: R-HSA-163560 CU254_RS36890 a9f73059bd244a23a40cc5e55623c6c5 350 Gene3D G3DSA:3.40.50.1820 40 349 2.7E-62 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS36890 a9f73059bd244a23a40cc5e55623c6c5 350 SUPERFAMILY SSF53474 81 342 5.55E-75 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS36890 a9f73059bd244a23a40cc5e55623c6c5 350 Pfam PF07859 alpha/beta hydrolase fold 116 322 5.4E-74 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CU254_RS06005 c4a6526269928bf853431b5b4cd47e3c 297 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 53 166 7.6E-18 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CU254_RS06005 c4a6526269928bf853431b5b4cd47e3c 297 Gene3D G3DSA:1.10.3720.10 47 271 1.2E-39 T 28-03-2018 CU254_RS06005 c4a6526269928bf853431b5b4cd47e3c 297 SUPERFAMILY SSF161098 55 263 1.07E-42 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS06005 c4a6526269928bf853431b5b4cd47e3c 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 72 270 9.5E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS00605 e9826365ebc5ff8ee7170ff969550d62 181 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 30 168 1.3E-21 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS00605 e9826365ebc5ff8ee7170ff969550d62 181 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 17 168 4.7E-49 T 28-03-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 CU254_RS00605 e9826365ebc5ff8ee7170ff969550d62 181 SUPERFAMILY SSF88946 19 106 2.31E-11 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS00605 e9826365ebc5ff8ee7170ff969550d62 181 Pfam PF08281 Sigma-70, region 4 112 164 1.4E-16 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS00605 e9826365ebc5ff8ee7170ff969550d62 181 Gene3D G3DSA:1.10.10.10 90 171 6.8E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS00605 e9826365ebc5ff8ee7170ff969550d62 181 SUPERFAMILY SSF88659 108 169 6.73E-16 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS00605 e9826365ebc5ff8ee7170ff969550d62 181 Gene3D G3DSA:1.10.1740.10 13 89 8.6E-12 T 28-03-2018 CU254_RS00605 e9826365ebc5ff8ee7170ff969550d62 181 Pfam PF04542 Sigma-70 region 2 29 89 8.6E-9 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS25595 84ed2979fc62d02d286617aab0463587 219 Gene3D G3DSA:1.10.357.10 69 215 1.9E-22 T 28-03-2018 CU254_RS25595 84ed2979fc62d02d286617aab0463587 219 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 68 8.5E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS25595 84ed2979fc62d02d286617aab0463587 219 SUPERFAMILY SSF46689 10 90 5.13E-21 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS25595 84ed2979fc62d02d286617aab0463587 219 Gene3D G3DSA:1.10.10.60 1 68 1.5E-21 T 28-03-2018 CU254_RS25595 84ed2979fc62d02d286617aab0463587 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 5.6E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS25595 84ed2979fc62d02d286617aab0463587 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 5.6E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS25595 84ed2979fc62d02d286617aab0463587 219 SUPERFAMILY SSF48498 88 213 5.34E-35 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS27590 e7e1edc59295806f3b33a54b8d190f98 558 Gene3D G3DSA:3.40.50.300 2 287 2.2E-58 T 28-03-2018 CU254_RS27590 e7e1edc59295806f3b33a54b8d190f98 558 SUPERFAMILY SSF52540 308 507 1.1E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS27590 e7e1edc59295806f3b33a54b8d190f98 558 Pfam PF12848 ABC transporter 227 302 1.3E-13 T 28-03-2018 IPR032781 ABC-transporter extension domain CU254_RS27590 e7e1edc59295806f3b33a54b8d190f98 558 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 3 555 1.9E-268 T 28-03-2018 IPR022374 ABC transporter, ATP-binding protein, ChvD CU254_RS27590 e7e1edc59295806f3b33a54b8d190f98 558 SUPERFAMILY SSF52540 8 240 2.1E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS27590 e7e1edc59295806f3b33a54b8d190f98 558 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS27590 e7e1edc59295806f3b33a54b8d190f98 558 Gene3D G3DSA:3.40.50.300 288 545 7.6E-48 T 28-03-2018 CU254_RS27590 e7e1edc59295806f3b33a54b8d190f98 558 SMART SM00382 30 239 4.8E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS27590 e7e1edc59295806f3b33a54b8d190f98 558 SMART SM00382 346 516 6.3E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS27590 e7e1edc59295806f3b33a54b8d190f98 558 Pfam PF00005 ABC transporter 338 471 3.8E-19 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS27590 e7e1edc59295806f3b33a54b8d190f98 558 Pfam PF00005 ABC transporter 21 188 3.1E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS27590 e7e1edc59295806f3b33a54b8d190f98 558 ProSitePatterns PS00211 ABC transporters family signature. 443 457 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS32745 4a16e17c10dfa3d06e97053b95c56236 469 Gene3D G3DSA:1.10.10.60 142 206 1.6E-8 T 28-03-2018 CU254_RS32745 4a16e17c10dfa3d06e97053b95c56236 469 Gene3D G3DSA:1.10.10.60 87 141 2.6E-4 T 28-03-2018 CU254_RS32745 4a16e17c10dfa3d06e97053b95c56236 469 Gene3D G3DSA:3.30.310.20 209 310 1.4E-38 T 28-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal CU254_RS32745 4a16e17c10dfa3d06e97053b95c56236 469 SMART SM00342 107 190 3.9E-19 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS32745 4a16e17c10dfa3d06e97053b95c56236 469 SUPERFAMILY SSF55945 210 304 3.45E-24 T 28-03-2018 CU254_RS32745 4a16e17c10dfa3d06e97053b95c56236 469 Gene3D G3DSA:1.10.1670.10 436 465 1.1E-4 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CU254_RS32745 4a16e17c10dfa3d06e97053b95c56236 469 SUPERFAMILY SSF46689 144 192 2.6E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS32745 4a16e17c10dfa3d06e97053b95c56236 469 SUPERFAMILY SSF57884 8 92 1.57E-30 T 28-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 CU254_RS32745 4a16e17c10dfa3d06e97053b95c56236 469 Gene3D G3DSA:1.10.340.30 311 435 6.1E-9 T 28-03-2018 CU254_RS32745 4a16e17c10dfa3d06e97053b95c56236 469 SMART SM01009 209 324 7.7E-49 T 28-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal CU254_RS32745 4a16e17c10dfa3d06e97053b95c56236 469 Pfam PF06029 AlkA N-terminal domain 210 324 1.3E-33 T 28-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal CU254_RS32745 4a16e17c10dfa3d06e97053b95c56236 469 SUPERFAMILY SSF48150 315 464 2.92E-11 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CU254_RS32745 4a16e17c10dfa3d06e97053b95c56236 469 Pfam PF02805 Metal binding domain of Ada 15 78 1.9E-28 T 28-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 CU254_RS32745 4a16e17c10dfa3d06e97053b95c56236 469 Gene3D G3DSA:3.40.10.10 7 80 4.5E-26 T 28-03-2018 IPR035451 Ada-like domain CU254_RS32745 4a16e17c10dfa3d06e97053b95c56236 469 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 144 186 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CU254_RS32745 4a16e17c10dfa3d06e97053b95c56236 469 Pfam PF12833 Helix-turn-helix domain 113 191 1.1E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS32575 995efdd2b5a3386cf1df1dec7493c860 451 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 261 366 1.6E-26 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CU254_RS32575 995efdd2b5a3386cf1df1dec7493c860 451 SUPERFAMILY SSF53738 259 363 4.71E-31 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CU254_RS32575 995efdd2b5a3386cf1df1dec7493c860 451 Gene3D G3DSA:3.30.310.50 364 451 6.8E-21 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CU254_RS32575 995efdd2b5a3386cf1df1dec7493c860 451 Gene3D G3DSA:3.40.120.10 271 363 7.3E-29 T 28-03-2018 CU254_RS32575 995efdd2b5a3386cf1df1dec7493c860 451 SUPERFAMILY SSF53738 9 165 1.96E-31 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CU254_RS32575 995efdd2b5a3386cf1df1dec7493c860 451 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 204 217 2.4E-21 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CU254_RS32575 995efdd2b5a3386cf1df1dec7493c860 451 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 93 107 2.4E-21 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CU254_RS32575 995efdd2b5a3386cf1df1dec7493c860 451 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 170 189 2.4E-21 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CU254_RS32575 995efdd2b5a3386cf1df1dec7493c860 451 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 233 248 2.4E-21 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CU254_RS32575 995efdd2b5a3386cf1df1dec7493c860 451 Gene3D G3DSA:3.40.120.10 159 270 5.8E-35 T 28-03-2018 CU254_RS32575 995efdd2b5a3386cf1df1dec7493c860 451 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 154 253 5.7E-25 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CU254_RS32575 995efdd2b5a3386cf1df1dec7493c860 451 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 372 449 8.6E-14 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CU254_RS32575 995efdd2b5a3386cf1df1dec7493c860 451 Gene3D G3DSA:3.40.120.10 6 158 1.9E-33 T 28-03-2018 CU254_RS32575 995efdd2b5a3386cf1df1dec7493c860 451 SUPERFAMILY SSF55957 367 451 8.5E-19 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CU254_RS32575 995efdd2b5a3386cf1df1dec7493c860 451 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 8 133 2.1E-31 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CU254_RS32575 995efdd2b5a3386cf1df1dec7493c860 451 SUPERFAMILY SSF53738 153 255 6.67E-30 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CU254_RS11895 021a3531d91d779d42059d81263f616e 225 Gene3D G3DSA:3.30.420.60 85 214 1.7E-21 T 28-03-2018 CU254_RS11895 021a3531d91d779d42059d81263f616e 225 SUPERFAMILY SSF53137 85 211 1.19E-20 T 28-03-2018 CU254_RS33525 41a843cc397ab38e547d61d3d4a4fb73 341 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 248 312 1.9E-19 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CU254_RS33525 41a843cc397ab38e547d61d3d4a4fb73 341 SMART SM00382 46 246 9.4E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS33525 41a843cc397ab38e547d61d3d4a4fb73 341 Gene3D G3DSA:3.40.50.300 14 340 3.5E-76 T 28-03-2018 CU254_RS33525 41a843cc397ab38e547d61d3d4a4fb73 341 SUPERFAMILY SSF52540 17 267 9.97E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS33525 41a843cc397ab38e547d61d3d4a4fb73 341 Pfam PF00005 ABC transporter 37 196 3.5E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS33525 41a843cc397ab38e547d61d3d4a4fb73 341 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 246 332 3.3E-26 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CU254_RS33525 41a843cc397ab38e547d61d3d4a4fb73 341 ProSitePatterns PS00211 ABC transporters family signature. 169 183 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS36565 620c71ee821c383eab8dc04f40dc5d53 584 Gene3D G3DSA:3.40.710.10 69 407 1.2E-84 T 28-03-2018 CU254_RS36565 620c71ee821c383eab8dc04f40dc5d53 584 Gene3D G3DSA:2.60.120.260 408 561 9.9E-11 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS36565 620c71ee821c383eab8dc04f40dc5d53 584 SUPERFAMILY SSF56601 84 408 9.6E-84 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CU254_RS36565 620c71ee821c383eab8dc04f40dc5d53 584 Pfam PF00144 Beta-lactamase 86 413 2.8E-75 T 28-03-2018 IPR001466 Beta-lactamase-related CU254_RS16105 8e8d418d17fdab9f377a978a4f0d85f1 2086 Gene3D G3DSA:1.10.1200.10 1996 2064 1.1E-24 T 28-03-2018 CU254_RS16105 8e8d418d17fdab9f377a978a4f0d85f1 2086 Gene3D G3DSA:1.10.1200.10 963 1030 3.4E-18 T 28-03-2018 CU254_RS16105 8e8d418d17fdab9f377a978a4f0d85f1 2086 SUPERFAMILY SSF56801 444 966 4.71E-154 T 28-03-2018 CU254_RS16105 8e8d418d17fdab9f377a978a4f0d85f1 2086 Pfam PF00668 Condensation domain 37 466 7.0E-101 T 28-03-2018 IPR001242 Condensation domain CU254_RS16105 8e8d418d17fdab9f377a978a4f0d85f1 2086 Pfam PF00668 Condensation domain 1053 1432 1.2E-39 T 28-03-2018 IPR001242 Condensation domain CU254_RS16105 8e8d418d17fdab9f377a978a4f0d85f1 2086 Gene3D G3DSA:3.30.559.10 1031 1243 1.0E-27 T 28-03-2018 CU254_RS16105 8e8d418d17fdab9f377a978a4f0d85f1 2086 SUPERFAMILY SSF56801 1487 2004 1.22E-140 T 28-03-2018 CU254_RS16105 8e8d418d17fdab9f377a978a4f0d85f1 2086 Gene3D G3DSA:3.30.300.30 1881 1995 1.4E-35 T 28-03-2018 CU254_RS16105 8e8d418d17fdab9f377a978a4f0d85f1 2086 Gene3D G3DSA:3.30.300.30 850 962 1.9E-36 T 28-03-2018 CU254_RS16105 8e8d418d17fdab9f377a978a4f0d85f1 2086 Gene3D G3DSA:3.40.50.980 612 764 2.3E-42 T 28-03-2018 CU254_RS16105 8e8d418d17fdab9f377a978a4f0d85f1 2086 Gene3D G3DSA:3.40.50.980 1641 1797 1.2E-31 T 28-03-2018 CU254_RS16105 8e8d418d17fdab9f377a978a4f0d85f1 2086 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1636 1647 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS16105 8e8d418d17fdab9f377a978a4f0d85f1 2086 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2016 2031 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CU254_RS16105 8e8d418d17fdab9f377a978a4f0d85f1 2086 SUPERFAMILY SSF47336 951 1023 2.49E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS16105 8e8d418d17fdab9f377a978a4f0d85f1 2086 SUPERFAMILY SSF47336 1984 2057 7.85E-21 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS16105 8e8d418d17fdab9f377a978a4f0d85f1 2086 SUPERFAMILY SSF52777 1057 1231 1.04E-31 T 28-03-2018 CU254_RS16105 8e8d418d17fdab9f377a978a4f0d85f1 2086 Pfam PF00501 AMP-binding enzyme 494 854 6.1E-97 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS16105 8e8d418d17fdab9f377a978a4f0d85f1 2086 Pfam PF00501 AMP-binding enzyme 1494 1886 1.8E-92 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS16105 8e8d418d17fdab9f377a978a4f0d85f1 2086 SMART SM00823 Phosphopantetheine attachment site 956 1027 0.72 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS16105 8e8d418d17fdab9f377a978a4f0d85f1 2086 SMART SM00823 Phosphopantetheine attachment site 1992 2061 9.7E-8 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS16105 8e8d418d17fdab9f377a978a4f0d85f1 2086 Pfam PF00550 Phosphopantetheine attachment site 1995 2056 1.2E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS16105 8e8d418d17fdab9f377a978a4f0d85f1 2086 Pfam PF00550 Phosphopantetheine attachment site 962 1021 1.9E-7 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS16105 8e8d418d17fdab9f377a978a4f0d85f1 2086 Gene3D G3DSA:2.30.38.10 765 844 3.3E-26 T 28-03-2018 CU254_RS16105 8e8d418d17fdab9f377a978a4f0d85f1 2086 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1515 1910 1.1E-121 T 28-03-2018 IPR010071 Amino acid adenylation domain CU254_RS16105 8e8d418d17fdab9f377a978a4f0d85f1 2086 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 504 878 2.9E-131 T 28-03-2018 IPR010071 Amino acid adenylation domain CU254_RS16105 8e8d418d17fdab9f377a978a4f0d85f1 2086 Gene3D G3DSA:3.40.50.980 480 611 8.1E-35 T 28-03-2018 CU254_RS16105 8e8d418d17fdab9f377a978a4f0d85f1 2086 SUPERFAMILY SSF52777 1238 1461 1.22E-24 T 28-03-2018 CU254_RS16105 8e8d418d17fdab9f377a978a4f0d85f1 2086 SUPERFAMILY SSF52777 39 202 2.78E-50 T 28-03-2018 CU254_RS16105 8e8d418d17fdab9f377a978a4f0d85f1 2086 SUPERFAMILY SSF52777 209 450 5.56E-61 T 28-03-2018 CU254_RS16105 8e8d418d17fdab9f377a978a4f0d85f1 2086 Gene3D G3DSA:3.30.559.10 16 225 1.5E-45 T 28-03-2018 CU254_RS16105 8e8d418d17fdab9f377a978a4f0d85f1 2086 Pfam PF13193 AMP-binding enzyme C-terminal domain 863 933 2.5E-11 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS16105 8e8d418d17fdab9f377a978a4f0d85f1 2086 Pfam PF13193 AMP-binding enzyme C-terminal domain 1894 1966 2.6E-8 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS16105 8e8d418d17fdab9f377a978a4f0d85f1 2086 ProSitePatterns PS00012 Phosphopantetheine attachment site. 983 998 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CU254_RS16105 8e8d418d17fdab9f377a978a4f0d85f1 2086 Gene3D G3DSA:2.30.38.10 1798 1879 1.0E-20 T 28-03-2018 CU254_RS16105 8e8d418d17fdab9f377a978a4f0d85f1 2086 Gene3D G3DSA:3.40.50.980 1487 1640 1.7E-46 T 28-03-2018 CU254_RS16105 8e8d418d17fdab9f377a978a4f0d85f1 2086 ProSitePatterns PS00455 Putative AMP-binding domain signature. 606 617 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1515 1889 2.4E-131 T 28-03-2018 IPR010071 Amino acid adenylation domain CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2981 3354 4.3E-113 T 28-03-2018 IPR010071 Amino acid adenylation domain CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 3981 4353 8.8E-121 T 28-03-2018 IPR010071 Amino acid adenylation domain CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 513 884 1.4E-104 T 28-03-2018 IPR010071 Amino acid adenylation domain CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 ProSitePatterns PS00455 Putative AMP-binding domain signature. 3080 3091 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 SUPERFAMILY SSF52777 2504 2681 3.0E-42 T 28-03-2018 CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 Gene3D G3DSA:2.30.38.10 4239 4319 5.2E-22 T 28-03-2018 CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 Gene3D G3DSA:2.30.38.10 773 850 3.5E-24 T 28-03-2018 CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 SUPERFAMILY SSF52777 2047 2237 2.22E-33 T 28-03-2018 CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 Gene3D G3DSA:3.30.300.30 3325 3430 7.8E-39 T 28-03-2018 CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 Gene3D G3DSA:3.30.300.30 4324 4435 2.6E-37 T 28-03-2018 CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 Gene3D G3DSA:3.30.300.30 1861 1975 3.1E-37 T 28-03-2018 CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 Gene3D G3DSA:3.30.300.30 855 962 7.2E-35 T 28-03-2018 CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 SUPERFAMILY SSF52777 39 230 5.11E-49 T 28-03-2018 CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1994 2009 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 Pfam PF00550 Phosphopantetheine attachment site 3428 3491 5.0E-18 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 Pfam PF00550 Phosphopantetheine attachment site 961 1023 1.5E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 Pfam PF00550 Phosphopantetheine attachment site 4434 4495 1.6E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 Pfam PF00550 Phosphopantetheine attachment site 1972 2032 7.9E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 SUPERFAMILY SSF52777 1048 1214 1.1E-50 T 28-03-2018 CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 SUPERFAMILY SSF56801 1452 1983 2.75E-157 T 28-03-2018 CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 SUPERFAMILY SSF56801 3922 4445 7.98E-149 T 28-03-2018 CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 Gene3D G3DSA:3.40.50.980 609 772 9.9E-38 T 28-03-2018 CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 SUPERFAMILY SSF47336 3419 3492 8.64E-22 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 ProSitePatterns PS00455 Putative AMP-binding domain signature. 4082 4093 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 SUPERFAMILY SSF52777 217 462 4.56E-60 T 28-03-2018 CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 SUPERFAMILY SSF47336 4424 4496 3.8E-18 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1615 1626 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 SUPERFAMILY SSF52777 4688 4928 7.78E-40 T 28-03-2018 CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 2345 2491 6.1E-38 T 28-03-2018 IPR010060 Non-ribosomal peptide synthase CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 Gene3D G3DSA:3.30.559.10 2045 2223 1.7E-32 T 28-03-2018 CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 Gene3D G3DSA:3.30.559.10 4498 4687 1.3E-31 T 28-03-2018 CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 SUPERFAMILY SSF52777 3507 3699 1.33E-50 T 28-03-2018 CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 SUPERFAMILY SSF56801 2920 3440 1.13E-144 T 28-03-2018 CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 Gene3D G3DSA:3.40.50.980 2951 3085 4.8E-38 T 28-03-2018 CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 Gene3D G3DSA:3.40.50.980 1485 1620 7.5E-40 T 28-03-2018 CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 Gene3D G3DSA:3.40.50.980 3952 4087 7.6E-38 T 28-03-2018 CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 Gene3D G3DSA:3.40.50.980 484 608 1.9E-29 T 28-03-2018 CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 Gene3D G3DSA:2.30.38.10 1779 1859 9.4E-24 T 28-03-2018 CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 Gene3D G3DSA:2.30.38.10 3242 3323 7.5E-24 T 28-03-2018 CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 SUPERFAMILY SSF52777 1217 1478 3.11E-62 T 28-03-2018 CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4456 4471 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 Pfam PF13193 AMP-binding enzyme C-terminal domain 1874 1945 2.3E-9 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 Pfam PF13193 AMP-binding enzyme C-terminal domain 4337 4405 4.4E-9 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 Pfam PF13193 AMP-binding enzyme C-terminal domain 3338 3402 5.0E-11 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 Pfam PF13193 AMP-binding enzyme C-terminal domain 868 934 3.2E-9 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 Gene3D G3DSA:1.10.1200.10 1976 2044 8.7E-22 T 28-03-2018 CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 Gene3D G3DSA:3.40.50.980 3086 3241 7.6E-29 T 28-03-2018 CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 Gene3D G3DSA:3.40.50.980 1621 1778 1.9E-41 T 28-03-2018 CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 Gene3D G3DSA:3.40.50.980 4088 4234 1.2E-32 T 28-03-2018 CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3451 3466 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 SUPERFAMILY SSF52777 4508 4700 2.45E-40 T 28-03-2018 CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 SMART SM01294 3428 3492 0.001 T 28-03-2018 CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 SUPERFAMILY SSF52777 3685 3944 1.03E-61 T 28-03-2018 CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 SMART SM00823 Phosphopantetheine attachment site 959 1028 1.0E-10 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 SMART SM00823 Phosphopantetheine attachment site 1970 2038 6.9E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 SMART SM00823 Phosphopantetheine attachment site 4432 4500 4.0E-5 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 SMART SM00823 Phosphopantetheine attachment site 3427 3496 1.1E-9 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 SUPERFAMILY SSF52777 2682 2928 5.34E-59 T 28-03-2018 CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 ProSitePatterns PS00455 Putative AMP-binding domain signature. 611 622 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 Gene3D G3DSA:3.30.559.10 3497 3689 2.4E-43 T 28-03-2018 CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 SUPERFAMILY SSF47336 1962 2033 2.09E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 Pfam PF00668 Condensation domain 4512 4929 4.4E-66 T 28-03-2018 IPR001242 Condensation domain CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 Pfam PF00668 Condensation domain 2498 2937 4.7E-86 T 28-03-2018 IPR001242 Condensation domain CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 Pfam PF00668 Condensation domain 43 474 6.1E-97 T 28-03-2018 IPR001242 Condensation domain CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 Pfam PF00668 Condensation domain 3510 3941 8.0E-108 T 28-03-2018 IPR001242 Condensation domain CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 Pfam PF00668 Condensation domain 1046 1471 7.7E-96 T 28-03-2018 IPR001242 Condensation domain CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 Pfam PF00668 Condensation domain 2049 2468 1.2E-67 T 28-03-2018 IPR001242 Condensation domain CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 Gene3D G3DSA:3.30.559.10 1026 1233 9.6E-47 T 28-03-2018 CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 Gene3D G3DSA:3.30.559.10 2470 2696 7.0E-37 T 28-03-2018 CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 Gene3D G3DSA:3.30.559.10 31 233 4.1E-43 T 28-03-2018 CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 SUPERFAMILY SSF47336 951 1024 1.96E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 Pfam PF00501 AMP-binding enzyme 1494 1866 6.5E-94 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 Pfam PF00501 AMP-binding enzyme 2959 3330 1.3E-84 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 Pfam PF00501 AMP-binding enzyme 493 588 1.9E-19 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 Pfam PF00501 AMP-binding enzyme 3960 4329 2.8E-83 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 Pfam PF00501 AMP-binding enzyme 599 860 1.8E-61 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 ProSitePatterns PS00012 Phosphopantetheine attachment site. 983 998 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 SUPERFAMILY SSF56801 453 972 4.19E-138 T 28-03-2018 CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 Gene3D G3DSA:1.10.1200.10 963 1025 2.7E-23 T 28-03-2018 CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 Gene3D G3DSA:1.10.1200.10 3431 3496 3.4E-25 T 28-03-2018 CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 Gene3D G3DSA:1.10.1200.10 4436 4497 5.4E-20 T 28-03-2018 CU254_RS16010 e4dd7473905fdec675d1495f8798fa1a 4932 SUPERFAMILY SSF52777 2224 2469 4.89E-44 T 28-03-2018 CU254_RS09320 50856d2efd9337013cdc00e03382dcd0 172 Pfam PF09534 Tryptophan-associated transmembrane protein (Trp_oprn_chp) 2 165 1.0E-28 T 28-03-2018 IPR019051 Trp biosynthesis associated, transmembrane protein, Oprn/Chp CU254_RS32395 8b6e75833395ed3199c3a7cc73886a0a 266 Gene3D G3DSA:3.40.190.10 1 263 2.6E-4 T 28-03-2018 CU254_RS06190 29a53e68b82c411cc46abd274e014acd 490 Gene3D G3DSA:3.20.20.80 194 489 7.9E-46 T 28-03-2018 CU254_RS06190 29a53e68b82c411cc46abd274e014acd 490 SUPERFAMILY SSF49785 29 157 1.68E-10 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS06190 29a53e68b82c411cc46abd274e014acd 490 Gene3D G3DSA:2.60.120.260 25 157 1.0E-26 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS06190 29a53e68b82c411cc46abd274e014acd 490 SUPERFAMILY SSF51445 196 479 1.2E-55 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS06190 29a53e68b82c411cc46abd274e014acd 490 SMART SM00636 199 471 3.6E-6 T 28-03-2018 IPR011583 Chitinase II GO:0008061 CU254_RS06190 29a53e68b82c411cc46abd274e014acd 490 ProSitePatterns PS01095 Chitinases family 18 active site. 310 318 - T 28-03-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 CU254_RS06190 29a53e68b82c411cc46abd274e014acd 490 Pfam PF02018 Carbohydrate binding domain 29 141 4.9E-13 T 28-03-2018 IPR003305 Carbohydrate-binding, CenC-like GO:0016798 CU254_RS06190 29a53e68b82c411cc46abd274e014acd 490 Pfam PF00704 Glycosyl hydrolases family 18 202 471 1.1E-25 T 28-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 CU254_RS22515 94c7f48ecc77fac18f917dc487e36568 216 SMART SM00345 19 77 2.3E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS22515 94c7f48ecc77fac18f917dc487e36568 216 Gene3D G3DSA:1.20.120.530 80 216 1.0E-22 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS22515 94c7f48ecc77fac18f917dc487e36568 216 Pfam PF07729 FCD domain 95 203 1.7E-18 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS22515 94c7f48ecc77fac18f917dc487e36568 216 Gene3D G3DSA:1.10.10.10 2 79 8.1E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS22515 94c7f48ecc77fac18f917dc487e36568 216 SUPERFAMILY SSF48008 83 213 1.02E-17 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS22515 94c7f48ecc77fac18f917dc487e36568 216 SMART SM00895 87 208 1.6E-7 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS22515 94c7f48ecc77fac18f917dc487e36568 216 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 77 2.4E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS22515 94c7f48ecc77fac18f917dc487e36568 216 SUPERFAMILY SSF46785 11 81 7.58E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS26530 a3eee34aabe73d28691e70fa099858eb 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 226 4.4E-20 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS26530 a3eee34aabe73d28691e70fa099858eb 230 SMART SM00862 152 226 1.0E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS26530 a3eee34aabe73d28691e70fa099858eb 230 Gene3D G3DSA:1.10.10.10 127 230 6.2E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS26530 a3eee34aabe73d28691e70fa099858eb 230 Pfam PF00072 Response regulator receiver domain 8 116 1.1E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS26530 a3eee34aabe73d28691e70fa099858eb 230 SUPERFAMILY SSF52172 5 186 1.02E-40 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS26530 a3eee34aabe73d28691e70fa099858eb 230 Gene3D G3DSA:3.40.50.2300 1 126 6.7E-37 T 28-03-2018 CU254_RS26530 a3eee34aabe73d28691e70fa099858eb 230 SMART SM00448 6 116 4.1E-40 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS06485 9e035390efc4c92063e5fae3161f28d0 131 Pfam PF00581 Rhodanese-like domain 23 117 7.3E-10 T 28-03-2018 IPR001763 Rhodanese-like domain CU254_RS06485 9e035390efc4c92063e5fae3161f28d0 131 SMART SM00450 18 121 1.2E-13 T 28-03-2018 IPR001763 Rhodanese-like domain CU254_RS06485 9e035390efc4c92063e5fae3161f28d0 131 SUPERFAMILY SSF52821 18 126 6.55E-21 T 28-03-2018 IPR001763 Rhodanese-like domain CU254_RS06485 9e035390efc4c92063e5fae3161f28d0 131 Gene3D G3DSA:3.40.250.10 1 129 1.1E-21 T 28-03-2018 IPR001763 Rhodanese-like domain CU254_RS28210 8b7f0d03d8e64072fc455d2ea1758d4c 167 SUPERFAMILY SSF56300 2 164 4.52E-34 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CU254_RS28210 8b7f0d03d8e64072fc455d2ea1758d4c 167 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 2 145 6.7E-27 T 28-03-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 CU254_RS28210 8b7f0d03d8e64072fc455d2ea1758d4c 167 Gene3D G3DSA:3.60.21.10 1 161 4.6E-19 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CU254_RS28210 8b7f0d03d8e64072fc455d2ea1758d4c 167 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 2 152 6.1E-24 T 28-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 CU254_RS28930 a13b340226b533f3c5daa1d40a066cf5 874 Gene3D G3DSA:3.40.50.300 162 347 9.1E-25 T 28-03-2018 CU254_RS28930 a13b340226b533f3c5daa1d40a066cf5 874 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 299 311 - T 28-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 CU254_RS28930 a13b340226b533f3c5daa1d40a066cf5 874 Gene3D G3DSA:1.10.8.60 348 555 1.1E-44 T 28-03-2018 CU254_RS28930 a13b340226b533f3c5daa1d40a066cf5 874 SMART SM00382 605 758 5.2E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS28930 a13b340226b533f3c5daa1d40a066cf5 874 SMART SM00382 203 348 2.3E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS28930 a13b340226b533f3c5daa1d40a066cf5 874 SUPERFAMILY SSF52540 554 861 1.62E-80 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS28930 a13b340226b533f3c5daa1d40a066cf5 874 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 639 657 - T 28-03-2018 IPR028299 ClpA/B, conserved site 2 CU254_RS28930 a13b340226b533f3c5daa1d40a066cf5 874 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 609 627 2.5E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CU254_RS28930 a13b340226b533f3c5daa1d40a066cf5 874 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 716 730 2.5E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CU254_RS28930 a13b340226b533f3c5daa1d40a066cf5 874 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 654 672 2.5E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CU254_RS28930 a13b340226b533f3c5daa1d40a066cf5 874 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 683 701 2.5E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CU254_RS28930 a13b340226b533f3c5daa1d40a066cf5 874 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 208 324 3.2E-11 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CU254_RS28930 a13b340226b533f3c5daa1d40a066cf5 874 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 865 0.0 T 28-03-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0016485 CU254_RS28930 a13b340226b533f3c5daa1d40a066cf5 874 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 776 855 3.6E-23 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CU254_RS28930 a13b340226b533f3c5daa1d40a066cf5 874 Gene3D G3DSA:1.10.8.60 776 874 3.9E-21 T 28-03-2018 CU254_RS28930 a13b340226b533f3c5daa1d40a066cf5 874 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 97 150 4.7E-11 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CU254_RS28930 a13b340226b533f3c5daa1d40a066cf5 874 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 68 2.3E-15 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CU254_RS28930 a13b340226b533f3c5daa1d40a066cf5 874 SUPERFAMILY SSF81923 4 161 2.35E-41 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CU254_RS28930 a13b340226b533f3c5daa1d40a066cf5 874 SUPERFAMILY SSF52540 163 553 4.62E-92 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS28930 a13b340226b533f3c5daa1d40a066cf5 874 Gene3D G3DSA:1.10.1780.10 1 156 1.9E-40 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CU254_RS28930 a13b340226b533f3c5daa1d40a066cf5 874 Pfam PF07724 AAA domain (Cdc48 subfamily) 604 770 1.7E-54 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CU254_RS28930 a13b340226b533f3c5daa1d40a066cf5 874 Gene3D G3DSA:3.40.50.300 560 775 3.7E-53 T 28-03-2018 CU254_RS28930 a13b340226b533f3c5daa1d40a066cf5 874 SMART SM01086 776 865 1.3E-32 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CU254_RS17860 a22660288ab1cc81e2a1df97b2795c0d 807 SUPERFAMILY SSF101790 721 806 7.36E-23 T 28-03-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain CU254_RS17860 a22660288ab1cc81e2a1df97b2795c0d 807 SUPERFAMILY SSF103025 414 712 2.83E-92 T 28-03-2018 CU254_RS17860 a22660288ab1cc81e2a1df97b2795c0d 807 Gene3D G3DSA:2.40.30.110 717 794 3.2E-22 T 28-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CU254_RS17860 a22660288ab1cc81e2a1df97b2795c0d 807 Gene3D G3DSA:3.40.50.20 1 82 5.6E-5 T 28-03-2018 CU254_RS17860 a22660288ab1cc81e2a1df97b2795c0d 807 Gene3D G3DSA:3.30.1360.120 567 673 3.4E-23 T 28-03-2018 CU254_RS17860 a22660288ab1cc81e2a1df97b2795c0d 807 Gene3D G3DSA:4.10.1250.10 675 716 1.5E-13 T 28-03-2018 CU254_RS17860 a22660288ab1cc81e2a1df97b2795c0d 807 SUPERFAMILY SSF54373 212 324 3.69E-28 T 28-03-2018 CU254_RS17860 a22660288ab1cc81e2a1df97b2795c0d 807 Gene3D G3DSA:3.30.9.10 83 159 4.4E-9 T 28-03-2018 CU254_RS17860 a22660288ab1cc81e2a1df97b2795c0d 807 Pfam PF01266 FAD dependent oxidoreductase 3 360 2.4E-43 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CU254_RS17860 a22660288ab1cc81e2a1df97b2795c0d 807 SUPERFAMILY SSF51905 1 212 4.75E-59 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS17860 a22660288ab1cc81e2a1df97b2795c0d 807 SUPERFAMILY SSF51905 325 407 4.75E-59 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS17860 a22660288ab1cc81e2a1df97b2795c0d 807 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 703 794 1.9E-17 T 28-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CU254_RS17860 a22660288ab1cc81e2a1df97b2795c0d 807 Gene3D G3DSA:3.30.9.10 160 324 1.2E-35 T 28-03-2018 CU254_RS17860 a22660288ab1cc81e2a1df97b2795c0d 807 Pfam PF01571 Aminomethyltransferase folate-binding domain 421 697 1.0E-74 T 28-03-2018 IPR006222 Glycine cleavage T-protein-like, N-terminal CU254_RS17860 a22660288ab1cc81e2a1df97b2795c0d 807 Gene3D G3DSA:3.30.1360.120 416 566 1.5E-25 T 28-03-2018 CU254_RS17860 a22660288ab1cc81e2a1df97b2795c0d 807 Pfam PF16350 FAD dependent oxidoreductase central domain 364 419 1.9E-18 T 28-03-2018 IPR032503 FAD dependent oxidoreductase, central domain CU254_RS38270 fa1c823311f933e0208e5c5259a54c33 395 Gene3D G3DSA:1.20.1250.20 2 194 1.5E-20 T 28-03-2018 CU254_RS38270 fa1c823311f933e0208e5c5259a54c33 395 Gene3D G3DSA:1.20.1250.20 195 391 4.1E-10 T 28-03-2018 CU254_RS38270 fa1c823311f933e0208e5c5259a54c33 395 SUPERFAMILY SSF103473 6 381 3.79E-31 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS38270 fa1c823311f933e0208e5c5259a54c33 395 Pfam PF07690 Major Facilitator Superfamily 9 287 4.8E-14 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS35875 b48f88b68b46264cd60c007c911d0e38 247 Gene3D G3DSA:3.40.50.720 2 247 5.4E-62 T 28-03-2018 CU254_RS35875 b48f88b68b46264cd60c007c911d0e38 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 1.6E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS35875 b48f88b68b46264cd60c007c911d0e38 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.6E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS35875 b48f88b68b46264cd60c007c911d0e38 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 1.6E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS35875 b48f88b68b46264cd60c007c911d0e38 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 1.6E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS35875 b48f88b68b46264cd60c007c911d0e38 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.6E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS35875 b48f88b68b46264cd60c007c911d0e38 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.6E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS35875 b48f88b68b46264cd60c007c911d0e38 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 2.0E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS35875 b48f88b68b46264cd60c007c911d0e38 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 2.0E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS35875 b48f88b68b46264cd60c007c911d0e38 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 2.0E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS35875 b48f88b68b46264cd60c007c911d0e38 247 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 244 2.9E-55 T 28-03-2018 CU254_RS35875 b48f88b68b46264cd60c007c911d0e38 247 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 184 4.6E-4 T 28-03-2018 CU254_RS35875 b48f88b68b46264cd60c007c911d0e38 247 SUPERFAMILY SSF51735 8 246 5.0E-71 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS21880 de3c3ffd734ab8650b65962445ea113a 441 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 15 393 6.2E-24 T 28-03-2018 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 CU254_RS32290 0b22a868840f814c6999a1f166d6017e 202 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 6 177 2.6E-58 T 28-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 CU254_RS32290 0b22a868840f814c6999a1f166d6017e 202 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 178 3.0E-64 T 28-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 CU254_RS32290 0b22a868840f814c6999a1f166d6017e 202 Gene3D G3DSA:2.60.120.10 1 191 5.5E-63 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS32290 0b22a868840f814c6999a1f166d6017e 202 SUPERFAMILY SSF51182 1 198 3.29E-69 T 28-03-2018 IPR011051 RmlC-like cupin domain CU254_RS08100 9510e3f8189b0dc8fbded247b5d2cacb 414 SUPERFAMILY SSF55874 294 410 1.7E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS08100 9510e3f8189b0dc8fbded247b5d2cacb 414 Pfam PF07730 Histidine kinase 225 289 5.4E-14 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CU254_RS08100 9510e3f8189b0dc8fbded247b5d2cacb 414 Gene3D G3DSA:3.30.565.10 288 414 2.4E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS10240 aa5925918e1c6ed451ee681987fcbd18 1375 Gene3D G3DSA:3.30.565.10 455 646 4.0E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS10240 aa5925918e1c6ed451ee681987fcbd18 1375 SMART SM00387 536 648 4.3E-4 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS10240 aa5925918e1c6ed451ee681987fcbd18 1375 Pfam PF08376 Nitrate and nitrite sensing 78 318 9.0E-28 T 28-03-2018 IPR013587 Nitrate/nitrite sensing protein CU254_RS10240 aa5925918e1c6ed451ee681987fcbd18 1375 SUPERFAMILY SSF55874 522 647 7.46E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS10240 aa5925918e1c6ed451ee681987fcbd18 1375 Pfam PF00672 HAMP domain 356 418 5.5E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS29660 8eb8d49eaf68f3e9059420cc8395b24c 623 SUPERFAMILY SSF54416 93 202 2.49E-27 T 28-03-2018 IPR016182 Copper amine oxidase, N-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 CU254_RS29660 8eb8d49eaf68f3e9059420cc8395b24c 623 Gene3D G3DSA:3.10.450.40 1 97 6.8E-18 T 28-03-2018 CU254_RS29660 8eb8d49eaf68f3e9059420cc8395b24c 623 ProSitePatterns PS01164 Copper amine oxidase topaquinone signature. 358 371 - T 28-03-2018 IPR000269 Copper amine oxidase GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 CU254_RS29660 8eb8d49eaf68f3e9059420cc8395b24c 623 SUPERFAMILY SSF49998 203 617 1.7E-154 T 28-03-2018 IPR015798 Copper amine oxidase, C-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 CU254_RS29660 8eb8d49eaf68f3e9059420cc8395b24c 623 SUPERFAMILY SSF54416 6 89 1.07E-15 T 28-03-2018 IPR016182 Copper amine oxidase, N-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 CU254_RS29660 8eb8d49eaf68f3e9059420cc8395b24c 623 Gene3D G3DSA:2.70.98.20 186 622 1.4E-178 T 28-03-2018 IPR015798 Copper amine oxidase, C-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 CU254_RS29660 8eb8d49eaf68f3e9059420cc8395b24c 623 Pfam PF02728 Copper amine oxidase, N3 domain 94 195 7.2E-17 T 28-03-2018 IPR015802 Copper amine oxidase, N3-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 CU254_RS29660 8eb8d49eaf68f3e9059420cc8395b24c 623 Pfam PF01179 Copper amine oxidase, enzyme domain 213 614 1.2E-154 T 28-03-2018 IPR015798 Copper amine oxidase, C-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 CU254_RS29660 8eb8d49eaf68f3e9059420cc8395b24c 623 Gene3D G3DSA:3.10.450.40 99 185 3.8E-24 T 28-03-2018 CU254_RS19605 a25ae4b2fb6743ed1f036df90c5898d6 828 Gene3D G3DSA:3.40.50.720 180 597 0.12 T 28-03-2018 CU254_RS19605 a25ae4b2fb6743ed1f036df90c5898d6 828 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 618 786 6.3E-44 T 28-03-2018 CU254_RS19605 a25ae4b2fb6743ed1f036df90c5898d6 828 Gene3D G3DSA:3.40.50.720 609 826 4.8E-45 T 28-03-2018 CU254_RS19605 a25ae4b2fb6743ed1f036df90c5898d6 828 Pfam PF13671 AAA domain 4 122 7.2E-8 T 28-03-2018 CU254_RS19605 a25ae4b2fb6743ed1f036df90c5898d6 828 Pfam PF08659 KR domain 618 784 3.1E-45 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS19605 a25ae4b2fb6743ed1f036df90c5898d6 828 SUPERFAMILY SSF51735 616 821 1.16E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS19605 a25ae4b2fb6743ed1f036df90c5898d6 828 Gene3D G3DSA:3.40.50.300 1 131 1.9E-12 T 28-03-2018 CU254_RS19605 a25ae4b2fb6743ed1f036df90c5898d6 828 SUPERFAMILY SSF52540 1 124 2.66E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS24110 131cd000c11186a58685b62719740be3 876 SMART SM00421 815 872 5.2E-23 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS24110 131cd000c11186a58685b62719740be3 876 Gene3D G3DSA:1.25.40.10 629 827 2.3E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS24110 131cd000c11186a58685b62719740be3 876 Gene3D G3DSA:1.10.10.10 828 872 1.1E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS24110 131cd000c11186a58685b62719740be3 876 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 832 848 1.6E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS24110 131cd000c11186a58685b62719740be3 876 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 818 832 1.6E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS24110 131cd000c11186a58685b62719740be3 876 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 848 860 1.6E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS24110 131cd000c11186a58685b62719740be3 876 Gene3D G3DSA:1.25.40.10 306 628 2.7E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS24110 131cd000c11186a58685b62719740be3 876 Gene3D G3DSA:3.40.50.300 1 154 3.0E-9 T 28-03-2018 CU254_RS24110 131cd000c11186a58685b62719740be3 876 Pfam PF00196 Bacterial regulatory proteins, luxR family 817 871 2.7E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS24110 131cd000c11186a58685b62719740be3 876 SUPERFAMILY SSF46894 811 871 6.46E-18 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS24110 131cd000c11186a58685b62719740be3 876 ProSitePatterns PS00622 LuxR-type HTH domain signature. 832 859 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS24110 131cd000c11186a58685b62719740be3 876 SUPERFAMILY SSF48452 474 617 4.83E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS24110 131cd000c11186a58685b62719740be3 876 SUPERFAMILY SSF48452 673 780 7.11E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS24110 131cd000c11186a58685b62719740be3 876 SUPERFAMILY SSF52540 13 194 6.26E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS02100 a8a13f9d92921a4c071d51e47d9f68c2 357 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 24 218 1.4E-19 T 28-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CU254_RS02100 a8a13f9d92921a4c071d51e47d9f68c2 357 SUPERFAMILY SSF56553 48 169 1.19E-42 T 28-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CU254_RS02100 a8a13f9d92921a4c071d51e47d9f68c2 357 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 250 320 1.0E-23 T 28-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CU254_RS02100 a8a13f9d92921a4c071d51e47d9f68c2 357 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 1 311 34.405 T 28-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CU254_RS02100 a8a13f9d92921a4c071d51e47d9f68c2 357 SUPERFAMILY SSF55257 170 220 2.22E-25 T 28-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CU254_RS02100 a8a13f9d92921a4c071d51e47d9f68c2 357 SUPERFAMILY SSF55257 13 48 2.22E-25 T 28-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CU254_RS02100 a8a13f9d92921a4c071d51e47d9f68c2 357 Gene3D G3DSA:3.30.1360.10 106 221 1.6E-27 T 28-03-2018 CU254_RS02100 a8a13f9d92921a4c071d51e47d9f68c2 357 Gene3D G3DSA:3.30.1360.10 4 83 5.0E-17 T 28-03-2018 CU254_RS02100 a8a13f9d92921a4c071d51e47d9f68c2 357 SUPERFAMILY SSF47789 246 318 1.57E-23 T 28-03-2018 CU254_RS02100 a8a13f9d92921a4c071d51e47d9f68c2 357 SMART SM00662 18 225 1.4E-96 T 28-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CU254_RS02100 a8a13f9d92921a4c071d51e47d9f68c2 357 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 242 301 9.7E-26 T 28-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CU254_RS02100 a8a13f9d92921a4c071d51e47d9f68c2 357 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 19 310 1.3E-114 T 28-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CU254_RS02100 a8a13f9d92921a4c071d51e47d9f68c2 357 Gene3D G3DSA:1.10.150.20 239 322 6.1E-24 T 28-03-2018 CU254_RS02100 a8a13f9d92921a4c071d51e47d9f68c2 357 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 57 149 2.2E-25 T 28-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CU254_RS10940 fbba158bb75279d0d8b7e9792e8ada27 489 Pfam PF00171 Aldehyde dehydrogenase family 10 475 8.7E-171 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CU254_RS10940 fbba158bb75279d0d8b7e9792e8ada27 489 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 247 254 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CU254_RS10940 fbba158bb75279d0d8b7e9792e8ada27 489 Gene3D G3DSA:3.40.605.10 1 263 3.5E-99 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CU254_RS10940 fbba158bb75279d0d8b7e9792e8ada27 489 Gene3D G3DSA:3.40.309.10 264 461 5.8E-73 T 28-03-2018 CU254_RS10940 fbba158bb75279d0d8b7e9792e8ada27 489 SUPERFAMILY SSF53720 3 479 8.25E-168 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CU254_RS10940 fbba158bb75279d0d8b7e9792e8ada27 489 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 275 286 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CU254_RS31780 b720b570be71dcf458f037518ac5f516 285 Gene3D G3DSA:3.40.190.10 91 176 2.2E-19 T 28-03-2018 CU254_RS31780 b720b570be71dcf458f037518ac5f516 285 Gene3D G3DSA:3.40.190.10 177 261 8.3E-22 T 28-03-2018 CU254_RS31780 b720b570be71dcf458f037518ac5f516 285 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.9E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS31780 b720b570be71dcf458f037518ac5f516 285 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.9E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS31780 b720b570be71dcf458f037518ac5f516 285 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.9E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS31780 b720b570be71dcf458f037518ac5f516 285 SUPERFAMILY SSF46785 1 84 5.23E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS31780 b720b570be71dcf458f037518ac5f516 285 SUPERFAMILY SSF53850 90 284 1.9E-37 T 28-03-2018 CU254_RS31780 b720b570be71dcf458f037518ac5f516 285 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 2.2E-23 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS31780 b720b570be71dcf458f037518ac5f516 285 Pfam PF03466 LysR substrate binding domain 88 284 1.6E-37 T 28-03-2018 IPR005119 LysR, substrate-binding CU254_RS31780 b720b570be71dcf458f037518ac5f516 285 Gene3D G3DSA:1.10.10.10 1 83 1.1E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS12960 b2bf8ae0d05055e1c90dd1f492eeedeb 2333 SUPERFAMILY SSF52777 968 1121 7.23E-39 T 28-03-2018 CU254_RS12960 b2bf8ae0d05055e1c90dd1f492eeedeb 2333 SUPERFAMILY SSF47336 1878 1947 1.96E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS12960 b2bf8ae0d05055e1c90dd1f492eeedeb 2333 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1526 1537 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS12960 b2bf8ae0d05055e1c90dd1f492eeedeb 2333 SUPERFAMILY SSF47336 878 949 1.03E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS12960 b2bf8ae0d05055e1c90dd1f492eeedeb 2333 SUPERFAMILY SSF52777 4 180 3.45E-38 T 28-03-2018 CU254_RS12960 b2bf8ae0d05055e1c90dd1f492eeedeb 2333 Gene3D G3DSA:2.30.38.10 691 776 2.3E-21 T 28-03-2018 CU254_RS12960 b2bf8ae0d05055e1c90dd1f492eeedeb 2333 Gene3D G3DSA:2.30.38.10 1693 1774 7.2E-23 T 28-03-2018 CU254_RS12960 b2bf8ae0d05055e1c90dd1f492eeedeb 2333 SUPERFAMILY SSF56801 383 896 9.03E-140 T 28-03-2018 CU254_RS12960 b2bf8ae0d05055e1c90dd1f492eeedeb 2333 SUPERFAMILY SSF52777 166 393 4.56E-48 T 28-03-2018 CU254_RS12960 b2bf8ae0d05055e1c90dd1f492eeedeb 2333 Gene3D G3DSA:3.30.559.10 1 176 7.7E-36 T 28-03-2018 CU254_RS12960 b2bf8ae0d05055e1c90dd1f492eeedeb 2333 Pfam PF00550 Phosphopantetheine attachment site 1885 1946 2.1E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS12960 b2bf8ae0d05055e1c90dd1f492eeedeb 2333 Pfam PF00550 Phosphopantetheine attachment site 888 948 1.0E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS12960 b2bf8ae0d05055e1c90dd1f492eeedeb 2333 ProSitePatterns PS00012 Phosphopantetheine attachment site. 907 922 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CU254_RS12960 b2bf8ae0d05055e1c90dd1f492eeedeb 2333 SUPERFAMILY SSF52777 2120 2301 1.08E-13 T 28-03-2018 CU254_RS12960 b2bf8ae0d05055e1c90dd1f492eeedeb 2333 SUPERFAMILY SSF52777 1957 2112 5.0E-27 T 28-03-2018 CU254_RS12960 b2bf8ae0d05055e1c90dd1f492eeedeb 2333 Gene3D G3DSA:3.30.300.30 781 888 5.4E-27 T 28-03-2018 CU254_RS12960 b2bf8ae0d05055e1c90dd1f492eeedeb 2333 Gene3D G3DSA:3.30.300.30 1779 1889 1.5E-27 T 28-03-2018 CU254_RS12960 b2bf8ae0d05055e1c90dd1f492eeedeb 2333 Gene3D G3DSA:1.10.1200.10 1890 1945 1.0E-20 T 28-03-2018 CU254_RS12960 b2bf8ae0d05055e1c90dd1f492eeedeb 2333 SUPERFAMILY SSF52777 1124 1355 1.33E-55 T 28-03-2018 CU254_RS12960 b2bf8ae0d05055e1c90dd1f492eeedeb 2333 Gene3D G3DSA:3.30.559.10 957 1136 8.7E-30 T 28-03-2018 CU254_RS12960 b2bf8ae0d05055e1c90dd1f492eeedeb 2333 SMART SM00823 Phosphopantetheine attachment site 1882 1951 3.9E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS12960 b2bf8ae0d05055e1c90dd1f492eeedeb 2333 SMART SM00823 Phosphopantetheine attachment site 883 952 8.6E-9 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS12960 b2bf8ae0d05055e1c90dd1f492eeedeb 2333 ProSitePatterns PS00455 Putative AMP-binding domain signature. 540 551 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS12960 b2bf8ae0d05055e1c90dd1f492eeedeb 2333 Gene3D G3DSA:3.40.50.980 1382 1531 1.2E-40 T 28-03-2018 CU254_RS12960 b2bf8ae0d05055e1c90dd1f492eeedeb 2333 Pfam PF00668 Condensation domain 5 404 1.7E-72 T 28-03-2018 IPR001242 Condensation domain CU254_RS12960 b2bf8ae0d05055e1c90dd1f492eeedeb 2333 Pfam PF00668 Condensation domain 965 1372 2.9E-71 T 28-03-2018 IPR001242 Condensation domain CU254_RS12960 b2bf8ae0d05055e1c90dd1f492eeedeb 2333 Pfam PF00668 Condensation domain 2133 2204 7.8E-5 T 28-03-2018 IPR001242 Condensation domain CU254_RS12960 b2bf8ae0d05055e1c90dd1f492eeedeb 2333 Pfam PF00668 Condensation domain 1975 2117 1.0E-15 T 28-03-2018 IPR001242 Condensation domain CU254_RS12960 b2bf8ae0d05055e1c90dd1f492eeedeb 2333 Gene3D G3DSA:3.40.50.980 414 537 5.4E-34 T 28-03-2018 CU254_RS12960 b2bf8ae0d05055e1c90dd1f492eeedeb 2333 Pfam PF00501 AMP-binding enzyme 423 519 9.1E-24 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS12960 b2bf8ae0d05055e1c90dd1f492eeedeb 2333 Pfam PF00501 AMP-binding enzyme 1392 1784 1.5E-93 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS12960 b2bf8ae0d05055e1c90dd1f492eeedeb 2333 Pfam PF00501 AMP-binding enzyme 529 786 2.6E-63 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS12960 b2bf8ae0d05055e1c90dd1f492eeedeb 2333 Gene3D G3DSA:3.40.50.980 1532 1688 2.7E-36 T 28-03-2018 CU254_RS12960 b2bf8ae0d05055e1c90dd1f492eeedeb 2333 Gene3D G3DSA:3.40.50.980 538 690 1.1E-46 T 28-03-2018 CU254_RS12960 b2bf8ae0d05055e1c90dd1f492eeedeb 2333 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1411 1808 4.9E-123 T 28-03-2018 IPR010071 Amino acid adenylation domain CU254_RS12960 b2bf8ae0d05055e1c90dd1f492eeedeb 2333 Gene3D G3DSA:1.10.1200.10 889 956 1.4E-24 T 28-03-2018 CU254_RS12960 b2bf8ae0d05055e1c90dd1f492eeedeb 2333 SUPERFAMILY SSF56801 1362 1894 7.06E-142 T 28-03-2018 CU254_RS12960 b2bf8ae0d05055e1c90dd1f492eeedeb 2333 Gene3D G3DSA:3.30.559.10 1946 2126 2.4E-22 T 28-03-2018 CU254_RS12960 b2bf8ae0d05055e1c90dd1f492eeedeb 2333 Pfam PF13193 AMP-binding enzyme C-terminal domain 1792 1859 4.3E-6 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS26970 606b7bf20fe9dcb3899333b908f137d4 225 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 75 8.0E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS26970 606b7bf20fe9dcb3899333b908f137d4 225 Gene3D G3DSA:1.20.120.530 84 225 2.4E-25 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS26970 606b7bf20fe9dcb3899333b908f137d4 225 Gene3D G3DSA:1.10.10.10 1 83 4.0E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS26970 606b7bf20fe9dcb3899333b908f137d4 225 SUPERFAMILY SSF48008 82 221 2.88E-24 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS26970 606b7bf20fe9dcb3899333b908f137d4 225 SMART SM00345 18 76 8.9E-12 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS26970 606b7bf20fe9dcb3899333b908f137d4 225 SUPERFAMILY SSF46785 10 99 4.68E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS26970 606b7bf20fe9dcb3899333b908f137d4 225 Pfam PF07729 FCD domain 86 212 5.3E-21 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS26970 606b7bf20fe9dcb3899333b908f137d4 225 SMART SM00895 86 213 6.3E-16 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS05305 50e8bbaf1343af4b1d9d1a87d8f7be9f 185 SMART SM00867 13 182 8.5E-73 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CU254_RS05305 50e8bbaf1343af4b1d9d1a87d8f7be9f 185 Gene3D G3DSA:2.40.128.110 9 185 2.7E-60 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CU254_RS05305 50e8bbaf1343af4b1d9d1a87d8f7be9f 185 Pfam PF04264 YceI-like domain 14 180 1.2E-46 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CU254_RS05305 50e8bbaf1343af4b1d9d1a87d8f7be9f 185 SUPERFAMILY SSF101874 12 184 4.58E-60 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CU254_RS06435 cde84fe75f014a0fdc7bc3a3a88a4f2a 327 Gene3D G3DSA:3.40.50.2300 53 171 1.2E-30 T 28-03-2018 CU254_RS06435 cde84fe75f014a0fdc7bc3a3a88a4f2a 327 ProSitePatterns PS00356 LacI-type HTH domain signature. 1 19 - T 28-03-2018 CU254_RS06435 cde84fe75f014a0fdc7bc3a3a88a4f2a 327 Gene3D G3DSA:3.40.50.2300 172 302 4.0E-33 T 28-03-2018 CU254_RS06435 cde84fe75f014a0fdc7bc3a3a88a4f2a 327 Pfam PF13377 Periplasmic binding protein-like domain 166 322 2.6E-28 T 28-03-2018 CU254_RS06435 cde84fe75f014a0fdc7bc3a3a88a4f2a 327 Pfam PF00356 Bacterial regulatory proteins, lacI family 1 45 4.4E-16 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CU254_RS06435 cde84fe75f014a0fdc7bc3a3a88a4f2a 327 Gene3D G3DSA:1.10.260.40 1 52 4.3E-21 T 28-03-2018 CU254_RS06435 cde84fe75f014a0fdc7bc3a3a88a4f2a 327 SUPERFAMILY SSF47413 1 56 7.04E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS06435 cde84fe75f014a0fdc7bc3a3a88a4f2a 327 SMART SM00354 1 69 2.3E-22 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CU254_RS06435 cde84fe75f014a0fdc7bc3a3a88a4f2a 327 SUPERFAMILY SSF53822 59 322 2.16E-60 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CU254_RS35765 fc85961b77143003fc7d27210f997d6f 258 SMART SM00346 10 99 4.5E-18 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS35765 fc85961b77143003fc7d27210f997d6f 258 Gene3D G3DSA:3.30.450.40 82 258 2.7E-50 T 28-03-2018 IPR029016 GAF domain-like CU254_RS35765 fc85961b77143003fc7d27210f997d6f 258 Gene3D G3DSA:1.10.10.10 5 81 9.6E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS35765 fc85961b77143003fc7d27210f997d6f 258 Pfam PF09339 IclR helix-turn-helix domain 12 61 3.8E-11 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS35765 fc85961b77143003fc7d27210f997d6f 258 Pfam PF01614 Bacterial transcriptional regulator 128 249 7.5E-31 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal CU254_RS35765 fc85961b77143003fc7d27210f997d6f 258 SUPERFAMILY SSF46785 12 81 1.96E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS35765 fc85961b77143003fc7d27210f997d6f 258 SUPERFAMILY SSF55781 75 254 8.5E-47 T 28-03-2018 IPR029016 GAF domain-like CU254_RS21070 641815e60e31a91c284dd015a9e17b2b 364 SUPERFAMILY SSF46785 126 193 3.28E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS21070 641815e60e31a91c284dd015a9e17b2b 364 SUPERFAMILY SSF55781 180 362 1.37E-45 T 28-03-2018 IPR029016 GAF domain-like CU254_RS21070 641815e60e31a91c284dd015a9e17b2b 364 SMART SM00346 123 212 1.6E-18 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS21070 641815e60e31a91c284dd015a9e17b2b 364 Pfam PF09339 IclR helix-turn-helix domain 126 175 4.4E-12 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS21070 641815e60e31a91c284dd015a9e17b2b 364 Gene3D G3DSA:3.30.450.40 191 364 1.2E-46 T 28-03-2018 IPR029016 GAF domain-like CU254_RS21070 641815e60e31a91c284dd015a9e17b2b 364 Pfam PF01614 Bacterial transcriptional regulator 241 341 1.4E-27 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal CU254_RS21070 641815e60e31a91c284dd015a9e17b2b 364 Gene3D G3DSA:1.10.10.10 117 190 4.7E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS20315 31c2ef8b5e449d549e44065f601168ae 413 SUPERFAMILY SSF90002 252 312 3.14E-9 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CU254_RS20315 31c2ef8b5e449d549e44065f601168ae 413 SUPERFAMILY SSF90002 339 365 3.14E-9 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CU254_RS20315 31c2ef8b5e449d549e44065f601168ae 413 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 251 365 7.8E-17 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CU254_RS20315 31c2ef8b5e449d549e44065f601168ae 413 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 32 180 2.1E-12 T 28-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CU254_RS20315 31c2ef8b5e449d549e44065f601168ae 413 Gene3D G3DSA:3.30.1220.10 230 365 2.7E-16 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CU254_RS20315 31c2ef8b5e449d549e44065f601168ae 413 Gene3D G3DSA:3.40.50.300 18 180 5.0E-10 T 28-03-2018 CU254_RS20315 31c2ef8b5e449d549e44065f601168ae 413 SMART SM00833 249 365 2.0E-30 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CU254_RS16060 6aa3cc5037f9237ddc727fd997fcc1e3 283 SUPERFAMILY SSF53335 13 254 3.25E-38 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS16060 6aa3cc5037f9237ddc727fd997fcc1e3 283 Pfam PF13649 Methyltransferase domain 93 186 4.8E-13 T 28-03-2018 CU254_RS16060 6aa3cc5037f9237ddc727fd997fcc1e3 283 Gene3D G3DSA:3.40.50.150 39 283 6.7E-41 T 28-03-2018 CU254_RS33295 811a139ce213051a705a6ff798b056ec 297 SUPERFAMILY SSF51735 92 266 6.48E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS33295 811a139ce213051a705a6ff798b056ec 297 SUPERFAMILY SSF52283 29 120 2.67E-6 T 28-03-2018 CU254_RS33295 811a139ce213051a705a6ff798b056ec 297 Gene3D G3DSA:3.40.50.720 9 98 3.3E-16 T 28-03-2018 CU254_RS33295 811a139ce213051a705a6ff798b056ec 297 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 98 265 1.9E-42 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CU254_RS33295 811a139ce213051a705a6ff798b056ec 297 Gene3D G3DSA:3.40.50.720 99 267 6.5E-46 T 28-03-2018 CU254_RS01400 3024bb2ef0cec56643539ded4e04f1dc 517 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 6 512 3.4E-158 T 28-03-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS01400 3024bb2ef0cec56643539ded4e04f1dc 517 Pfam PF00361 Proton-conducting membrane transporter 131 427 8.0E-56 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS01400 3024bb2ef0cec56643539ded4e04f1dc 517 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 385 411 8.3E-28 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS01400 3024bb2ef0cec56643539ded4e04f1dc 517 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 333 352 8.3E-28 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS01400 3024bb2ef0cec56643539ded4e04f1dc 517 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 137 156 8.3E-28 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS01400 3024bb2ef0cec56643539ded4e04f1dc 517 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 245 269 8.3E-28 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS01400 3024bb2ef0cec56643539ded4e04f1dc 517 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 167 191 8.3E-28 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS15000 4a4a2ba309ae61e76d35691dfbeeb41d 221 Pfam PF08713 DNA alkylation repair enzyme 11 209 1.6E-19 T 28-03-2018 IPR014825 DNA alkylation repair enzyme CU254_RS15000 4a4a2ba309ae61e76d35691dfbeeb41d 221 Gene3D G3DSA:1.25.40.290 108 191 8.0E-4 T 28-03-2018 CU254_RS15000 4a4a2ba309ae61e76d35691dfbeeb41d 221 Gene3D G3DSA:1.20.1660.10 9 107 1.0E-4 T 28-03-2018 CU254_RS15000 4a4a2ba309ae61e76d35691dfbeeb41d 221 SUPERFAMILY SSF48371 6 220 1.06E-59 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 CU254_RS17565 724d98aa466ba62c5628929114f15d08 602 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 422 573 1.8E-34 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CU254_RS17565 724d98aa466ba62c5628929114f15d08 602 Gene3D G3DSA:3.40.50.970 12 195 1.3E-48 T 28-03-2018 CU254_RS17565 724d98aa466ba62c5628929114f15d08 602 SUPERFAMILY SSF52518 16 192 6.38E-46 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS17565 724d98aa466ba62c5628929114f15d08 602 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 19 185 3.8E-45 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CU254_RS17565 724d98aa466ba62c5628929114f15d08 602 Gene3D G3DSA:3.40.50.1220 197 403 2.4E-46 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CU254_RS17565 724d98aa466ba62c5628929114f15d08 602 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 204 341 8.3E-35 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CU254_RS17565 724d98aa466ba62c5628929114f15d08 602 TIGRFAM TIGR03457 sulphoacet_xsc: sulfoacetaldehyde acetyltransferase 18 598 0.0 T 28-03-2018 IPR017820 Sulphoacetaldehyde acetyltransferase GO:0000287|GO:0005737|GO:0019529|GO:0030976|GO:0050487 KEGG: 00430+2.3.3.15|MetaCyc: PWY-1281|MetaCyc: PWY-6637 CU254_RS17565 724d98aa466ba62c5628929114f15d08 602 SUPERFAMILY SSF52518 400 595 1.01E-47 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS17565 724d98aa466ba62c5628929114f15d08 602 SUPERFAMILY SSF52467 196 380 3.27E-42 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CU254_RS17565 724d98aa466ba62c5628929114f15d08 602 Gene3D G3DSA:3.40.50.970 404 589 3.9E-37 T 28-03-2018 CU254_RS05825 2a1a20f211e517c862645bf8c02c0e3b 246 Gene3D G3DSA:3.40.50.720 47 245 1.6E-64 T 28-03-2018 CU254_RS05825 2a1a20f211e517c862645bf8c02c0e3b 246 Gene3D G3DSA:3.40.50.720 1 46 4.7E-9 T 28-03-2018 CU254_RS05825 2a1a20f211e517c862645bf8c02c0e3b 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.7E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS05825 2a1a20f211e517c862645bf8c02c0e3b 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 3.7E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS05825 2a1a20f211e517c862645bf8c02c0e3b 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 3.7E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS05825 2a1a20f211e517c862645bf8c02c0e3b 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 3.7E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS05825 2a1a20f211e517c862645bf8c02c0e3b 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 3.7E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS05825 2a1a20f211e517c862645bf8c02c0e3b 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 3.7E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS05825 2a1a20f211e517c862645bf8c02c0e3b 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 1.3E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS05825 2a1a20f211e517c862645bf8c02c0e3b 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 1.3E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS05825 2a1a20f211e517c862645bf8c02c0e3b 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 1.3E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS05825 2a1a20f211e517c862645bf8c02c0e3b 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 244 2.3E-57 T 28-03-2018 CU254_RS05825 2a1a20f211e517c862645bf8c02c0e3b 246 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 183 1.0E-5 T 28-03-2018 CU254_RS05825 2a1a20f211e517c862645bf8c02c0e3b 246 SUPERFAMILY SSF51735 3 244 4.35E-76 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS27325 eee50aea12bcf76bec3965bc788162df 220 Gene3D G3DSA:2.30.180.10 81 214 2.9E-31 T 28-03-2018 IPR000782 FAS1 domain CU254_RS27325 eee50aea12bcf76bec3965bc788162df 220 SMART SM00554 117 216 7.4E-24 T 28-03-2018 IPR000782 FAS1 domain CU254_RS27325 eee50aea12bcf76bec3965bc788162df 220 SUPERFAMILY SSF82153 78 215 3.27E-30 T 28-03-2018 IPR000782 FAS1 domain CU254_RS27325 eee50aea12bcf76bec3965bc788162df 220 Pfam PF02469 Fasciclin domain 93 215 4.2E-30 T 28-03-2018 IPR000782 FAS1 domain CU254_RS26405 85585b9e286167a2b4c9a109ee8e496e 258 Gene3D G3DSA:2.40.50.140 2 82 1.5E-30 T 28-03-2018 CU254_RS26405 85585b9e286167a2b4c9a109ee8e496e 258 Pfam PF02565 Recombination protein O C terminal 87 239 1.1E-32 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CU254_RS26405 85585b9e286167a2b4c9a109ee8e496e 258 Hamap MF_00201 DNA repair protein RecO [recO]. 3 244 26.902 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CU254_RS26405 85585b9e286167a2b4c9a109ee8e496e 258 TIGRFAM TIGR00613 reco: DNA repair protein RecO 6 205 6.7E-38 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CU254_RS26405 85585b9e286167a2b4c9a109ee8e496e 258 SUPERFAMILY SSF57863 84 233 4.45E-39 T 28-03-2018 CU254_RS26405 85585b9e286167a2b4c9a109ee8e496e 258 SUPERFAMILY SSF50249 3 80 3.94E-22 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CU254_RS26405 85585b9e286167a2b4c9a109ee8e496e 258 Pfam PF11967 Recombination protein O N terminal 4 80 2.8E-27 T 28-03-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal CU254_RS17795 c05f66121306dbc1cacd1ba3530ce950 289 Pfam PF00535 Glycosyl transferase family 2 46 204 2.7E-22 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CU254_RS17795 c05f66121306dbc1cacd1ba3530ce950 289 SUPERFAMILY SSF53448 43 248 1.18E-33 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS17795 c05f66121306dbc1cacd1ba3530ce950 289 Gene3D G3DSA:3.90.550.10 18 270 2.6E-29 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS12060 28e84c0f3ab2a121f57f4702fb7b4ebe 147 Gene3D G3DSA:3.40.140.10 1 145 6.5E-33 T 28-03-2018 CU254_RS12060 28e84c0f3ab2a121f57f4702fb7b4ebe 147 SUPERFAMILY SSF53927 4 143 9.03E-35 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CU254_RS12060 28e84c0f3ab2a121f57f4702fb7b4ebe 147 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 5 97 3.3E-17 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CU254_RS12865 93f1c7a65bfb42631d2e352b746fbd8c 153 Gene3D G3DSA:3.10.129.10 11 153 1.3E-15 T 28-03-2018 CU254_RS12865 93f1c7a65bfb42631d2e352b746fbd8c 153 Pfam PF13452 N-terminal half of MaoC dehydratase 44 144 1.5E-9 T 28-03-2018 CU254_RS12865 93f1c7a65bfb42631d2e352b746fbd8c 153 SUPERFAMILY SSF54637 85 153 9.59E-9 T 28-03-2018 IPR029069 HotDog domain CU254_RS14550 6beac977c0b1615507a5181d97b67a5e 671 Gene3D G3DSA:3.40.50.2000 280 479 5.4E-15 T 28-03-2018 CU254_RS14550 6beac977c0b1615507a5181d97b67a5e 671 Pfam PF13439 Glycosyltransferase Family 4 299 476 3.7E-26 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CU254_RS14550 6beac977c0b1615507a5181d97b67a5e 671 Gene3D G3DSA:3.40.50.2000 480 638 1.2E-41 T 28-03-2018 CU254_RS14550 6beac977c0b1615507a5181d97b67a5e 671 SUPERFAMILY SSF53756 287 658 6.49E-77 T 28-03-2018 CU254_RS14550 6beac977c0b1615507a5181d97b67a5e 671 Pfam PF00534 Glycosyl transferases group 1 485 637 2.7E-33 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CU254_RS27155 52430899c09b52a89836b5b603bde480 112 SMART SM00418 10 84 9.8E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS27155 52430899c09b52a89836b5b603bde480 112 SUPERFAMILY SSF46785 5 104 2.53E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS27155 52430899c09b52a89836b5b603bde480 112 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 59 74 7.6E-5 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS27155 52430899c09b52a89836b5b603bde480 112 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 44 59 7.6E-5 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS27155 52430899c09b52a89836b5b603bde480 112 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 12 27 7.6E-5 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS27155 52430899c09b52a89836b5b603bde480 112 Pfam PF12840 Helix-turn-helix domain 11 68 4.8E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS27155 52430899c09b52a89836b5b603bde480 112 Gene3D G3DSA:1.10.10.10 1 111 1.5E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS23615 d057bed1c507b9f4af7edc2df0ef1af3 328 PIRSF PIRSF036407 1 308 4.8E-104 T 28-03-2018 IPR004536 Selenophosphate synthetase GO:0005524 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 CU254_RS23615 d057bed1c507b9f4af7edc2df0ef1af3 328 TIGRFAM TIGR00476 selD: selenide, water dikinase 2 306 1.5E-120 T 28-03-2018 IPR004536 Selenophosphate synthetase GO:0005524 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 CU254_RS23615 d057bed1c507b9f4af7edc2df0ef1af3 328 Gene3D G3DSA:3.30.1330.10 1 161 2.8E-34 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CU254_RS23615 d057bed1c507b9f4af7edc2df0ef1af3 328 SUPERFAMILY SSF56042 161 323 4.04E-36 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CU254_RS23615 d057bed1c507b9f4af7edc2df0ef1af3 328 Hamap MF_00625 Selenide, water dikinase [selD]. 1 328 37.184 T 28-03-2018 IPR023061 Selenophosphate synthetase, class I GO:0004756|GO:0005524|GO:0016260 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 CU254_RS23615 d057bed1c507b9f4af7edc2df0ef1af3 328 Gene3D G3DSA:3.90.650.10 162 308 5.4E-31 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CU254_RS23615 d057bed1c507b9f4af7edc2df0ef1af3 328 Pfam PF00586 AIR synthase related protein, N-terminal domain 48 154 7.1E-19 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CU254_RS23615 d057bed1c507b9f4af7edc2df0ef1af3 328 SUPERFAMILY SSF55326 2 159 4.06E-40 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CU254_RS23615 d057bed1c507b9f4af7edc2df0ef1af3 328 Pfam PF02769 AIR synthase related protein, C-terminal domain 167 305 4.5E-17 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CU254_RS04175 2f03827957783c39673de3a598c30012 335 ProSitePatterns PS00893 Nudix box signature. 219 240 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CU254_RS04175 2f03827957783c39673de3a598c30012 335 Gene3D G3DSA:3.90.79.10 181 335 1.1E-33 T 28-03-2018 CU254_RS04175 2f03827957783c39673de3a598c30012 335 Pfam PF00293 NUDIX domain 184 295 1.5E-17 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CU254_RS04175 2f03827957783c39673de3a598c30012 335 Pfam PF09296 NADH pyrophosphatase-like rudimentary NUDIX domain 60 146 1.8E-7 T 28-03-2018 IPR015375 NADH pyrophosphatase-like, N-terminal GO:0016787 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381|MetaCyc: PWY-7761 CU254_RS04175 2f03827957783c39673de3a598c30012 335 Pfam PF09297 NADH pyrophosphatase zinc ribbon domain 148 179 6.4E-6 T 28-03-2018 IPR015376 Zinc ribbon, NADH pyrophosphatase GO:0016787|GO:0046872 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381|MetaCyc: PWY-7761 CU254_RS04175 2f03827957783c39673de3a598c30012 335 SUPERFAMILY SSF55811 134 296 3.52E-41 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CU254_RS14525 96a5d2cc4d52d380b27a5c700ee78367 388 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 340 359 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CU254_RS14525 96a5d2cc4d52d380b27a5c700ee78367 388 SUPERFAMILY SSF47203 231 386 2.09E-49 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS14525 96a5d2cc4d52d380b27a5c700ee78367 388 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 219 9.9E-22 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CU254_RS14525 96a5d2cc4d52d380b27a5c700ee78367 388 SUPERFAMILY SSF56645 2 246 1.44E-63 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS14525 96a5d2cc4d52d380b27a5c700ee78367 388 Gene3D G3DSA:1.10.540.10 1 123 3.9E-32 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS14525 96a5d2cc4d52d380b27a5c700ee78367 388 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 233 379 3.9E-38 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS14525 96a5d2cc4d52d380b27a5c700ee78367 388 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 118 6.3E-26 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS14525 96a5d2cc4d52d380b27a5c700ee78367 388 Gene3D G3DSA:2.40.110.10 124 222 2.1E-27 T 28-03-2018 CU254_RS14525 96a5d2cc4d52d380b27a5c700ee78367 388 PIRSF PIRSF016578 3 201 0.0077 T 28-03-2018 CU254_RS14525 96a5d2cc4d52d380b27a5c700ee78367 388 PIRSF PIRSF016578 238 387 4.6E-11 T 28-03-2018 CU254_RS14525 96a5d2cc4d52d380b27a5c700ee78367 388 Gene3D G3DSA:1.20.140.10 223 388 1.5E-49 T 28-03-2018 CU254_RS21715 320a684dafe4ef15742b6cb0ad46c461 336 SUPERFAMILY SSF53901 8 207 1.59E-22 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS21715 320a684dafe4ef15742b6cb0ad46c461 336 Gene3D G3DSA:3.40.47.10 220 333 6.9E-7 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS21715 320a684dafe4ef15742b6cb0ad46c461 336 Gene3D G3DSA:3.40.47.10 3 219 6.7E-21 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS21715 320a684dafe4ef15742b6cb0ad46c461 336 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 49 183 1.5E-10 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CU254_RS21715 320a684dafe4ef15742b6cb0ad46c461 336 SUPERFAMILY SSF53901 194 321 5.38E-7 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS29020 3ffa105cbdb7a588be44fbd287cfe50a 541 Gene3D G3DSA:3.40.50.300 11 330 7.0E-52 T 28-03-2018 CU254_RS29020 3ffa105cbdb7a588be44fbd287cfe50a 541 Gene3D G3DSA:3.40.50.300 345 534 6.9E-39 T 28-03-2018 CU254_RS29020 3ffa105cbdb7a588be44fbd287cfe50a 541 SUPERFAMILY SSF52540 15 231 1.07E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS29020 3ffa105cbdb7a588be44fbd287cfe50a 541 SMART SM00382 369 535 1.9E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS29020 3ffa105cbdb7a588be44fbd287cfe50a 541 SMART SM00382 39 224 9.1E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS29020 3ffa105cbdb7a588be44fbd287cfe50a 541 Pfam PF00005 ABC transporter 363 490 3.8E-20 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS29020 3ffa105cbdb7a588be44fbd287cfe50a 541 Pfam PF00005 ABC transporter 35 180 3.2E-19 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS29020 3ffa105cbdb7a588be44fbd287cfe50a 541 SUPERFAMILY SSF52540 363 532 9.84E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS08450 34dd735c58e385e92799ab55bbdee205 118 Gene3D G3DSA:3.10.180.10 1 116 7.4E-21 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS08450 34dd735c58e385e92799ab55bbdee205 118 SUPERFAMILY SSF54593 5 116 4.65E-16 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS01100 62ce19ec5e8ad1c98b6d8f5406b37a74 203 Gene3D G3DSA:1.10.10.60 2 44 3.0E-7 T 28-03-2018 CU254_RS01100 62ce19ec5e8ad1c98b6d8f5406b37a74 203 SUPERFAMILY SSF46689 3 72 2.31E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS01100 62ce19ec5e8ad1c98b6d8f5406b37a74 203 Pfam PF13305 WHG domain 84 165 1.1E-14 T 28-03-2018 IPR025996 WHG domain CU254_RS01100 62ce19ec5e8ad1c98b6d8f5406b37a74 203 SUPERFAMILY SSF48498 84 174 8.16E-16 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS01100 62ce19ec5e8ad1c98b6d8f5406b37a74 203 Gene3D G3DSA:1.10.10.60 45 69 2.7E-4 T 28-03-2018 CU254_RS01100 62ce19ec5e8ad1c98b6d8f5406b37a74 203 Gene3D G3DSA:1.10.357.10 70 202 1.1E-16 T 28-03-2018 CU254_RS31130 73c740527b2384d39722b82508efabd7 333 TIGRFAM TIGR02363 dhaK1: dihydroxyacetone kinase, DhaK subunit 1 329 6.2E-139 T 28-03-2018 IPR012736 Dihydroxyacetone kinase DhaK, subunit 1 CU254_RS31130 73c740527b2384d39722b82508efabd7 333 Pfam PF02733 Dak1 domain 17 328 5.7E-123 T 28-03-2018 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CU254_RS31130 73c740527b2384d39722b82508efabd7 333 SUPERFAMILY SSF82549 11 332 9.16E-118 T 28-03-2018 CU254_RS31130 73c740527b2384d39722b82508efabd7 333 Gene3D G3DSA:3.30.1180.20 185 333 3.4E-50 T 28-03-2018 CU254_RS31130 73c740527b2384d39722b82508efabd7 333 Gene3D G3DSA:3.40.50.10440 11 184 3.6E-66 T 28-03-2018 CU254_RS06790 13ed25f4e249c3f7e7bab38472535a36 164 Pfam PF00583 Acetyltransferase (GNAT) family 33 141 2.0E-12 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS06790 13ed25f4e249c3f7e7bab38472535a36 164 Gene3D G3DSA:3.40.630.30 1 90 2.7E-15 T 28-03-2018 CU254_RS06790 13ed25f4e249c3f7e7bab38472535a36 164 Gene3D G3DSA:3.40.630.30 91 153 1.1E-14 T 28-03-2018 CU254_RS06790 13ed25f4e249c3f7e7bab38472535a36 164 SUPERFAMILY SSF55729 1 152 1.61E-26 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS25285 867218b33d23cbf4c94ccc9d2bba1360 329 Gene3D G3DSA:3.40.50.2300 57 162 3.1E-23 T 28-03-2018 CU254_RS25285 867218b33d23cbf4c94ccc9d2bba1360 329 SUPERFAMILY SSF53822 56 325 2.17E-67 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CU254_RS25285 867218b33d23cbf4c94ccc9d2bba1360 329 SUPERFAMILY SSF47413 2 45 1.15E-6 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS25285 867218b33d23cbf4c94ccc9d2bba1360 329 Gene3D G3DSA:3.40.50.2300 163 327 3.1E-48 T 28-03-2018 CU254_RS25285 867218b33d23cbf4c94ccc9d2bba1360 329 Pfam PF13377 Periplasmic binding protein-like domain 166 324 2.8E-38 T 28-03-2018 CU254_RS25285 867218b33d23cbf4c94ccc9d2bba1360 329 Gene3D G3DSA:1.10.260.40 1 56 9.8E-10 T 28-03-2018 CU254_RS25285 867218b33d23cbf4c94ccc9d2bba1360 329 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 40 6.5E-9 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CU254_RS25285 867218b33d23cbf4c94ccc9d2bba1360 329 SMART SM00354 1 65 5.0E-6 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CU254_RS36150 bdb2cbcd3a159ac97fe1fff25afcc825 474 SUPERFAMILY SSF63737 43 235 4.58E-33 T 28-03-2018 CU254_RS36150 bdb2cbcd3a159ac97fe1fff25afcc825 474 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 220 235 8.2E-7 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CU254_RS36150 bdb2cbcd3a159ac97fe1fff25afcc825 474 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 317 332 8.2E-7 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CU254_RS36150 bdb2cbcd3a159ac97fe1fff25afcc825 474 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 173 188 8.2E-7 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CU254_RS36150 bdb2cbcd3a159ac97fe1fff25afcc825 474 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 336 348 8.2E-7 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CU254_RS36150 bdb2cbcd3a159ac97fe1fff25afcc825 474 Gene3D G3DSA:1.10.390.10 301 459 5.5E-31 T 28-03-2018 CU254_RS36150 bdb2cbcd3a159ac97fe1fff25afcc825 474 Pfam PF01433 Peptidase family M1 domain 315 455 1.4E-19 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CU254_RS36150 bdb2cbcd3a159ac97fe1fff25afcc825 474 SUPERFAMILY SSF55486 265 462 1.98E-37 T 28-03-2018 CU254_RS36150 bdb2cbcd3a159ac97fe1fff25afcc825 474 Gene3D G3DSA:2.60.40.1730 52 238 1.6E-41 T 28-03-2018 CU254_RS11380 634b1de141f57b1e55d66477b3d6fc3d 78 Pfam PF00367 phosphotransferase system, EIIB 8 40 1.3E-13 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CU254_RS11380 634b1de141f57b1e55d66477b3d6fc3d 78 SUPERFAMILY SSF55604 7 77 2.22E-21 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CU254_RS11380 634b1de141f57b1e55d66477b3d6fc3d 78 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 3 64 1.2E-17 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CU254_RS11380 634b1de141f57b1e55d66477b3d6fc3d 78 Gene3D G3DSA:3.30.1360.60 3 78 1.2E-26 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CU254_RS14865 84dc8c928daa54cad13d9c0b20e671fb 182 Pfam PF03374 Phage antirepressor protein KilAC domain 69 175 1.8E-16 T 28-03-2018 IPR005039 Antirepressor protein, C-terminal GO:0003677 CU254_RS42075 c0a80e91f9008c57c7ed39284c4699f8 396 Pfam PF00857 Isochorismatase family 177 377 4.0E-32 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CU254_RS42075 c0a80e91f9008c57c7ed39284c4699f8 396 SUPERFAMILY SSF52499 167 386 3.27E-46 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CU254_RS42075 c0a80e91f9008c57c7ed39284c4699f8 396 Gene3D G3DSA:3.40.50.850 149 394 3.8E-46 T 28-03-2018 CU254_RS16795 ab9aaaf08936b93d80bb57bfac1270a9 309 Gene3D G3DSA:3.40.50.720 144 285 1.8E-23 T 28-03-2018 CU254_RS16795 ab9aaaf08936b93d80bb57bfac1270a9 309 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 89 1.8E-9 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CU254_RS16795 ab9aaaf08936b93d80bb57bfac1270a9 309 SUPERFAMILY SSF50129 1 144 7.3E-38 T 28-03-2018 IPR011032 GroES-like CU254_RS16795 ab9aaaf08936b93d80bb57bfac1270a9 309 Gene3D G3DSA:3.90.180.10 1 143 2.7E-43 T 28-03-2018 CU254_RS16795 ab9aaaf08936b93d80bb57bfac1270a9 309 SMART SM00829 10 307 6.8E-15 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CU254_RS16795 ab9aaaf08936b93d80bb57bfac1270a9 309 SUPERFAMILY SSF51735 118 243 4.42E-29 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS16795 ab9aaaf08936b93d80bb57bfac1270a9 309 Pfam PF13602 Zinc-binding dehydrogenase 188 307 3.0E-14 T 28-03-2018 CU254_RS26535 d12f2959388506b75592d62955307fc8 501 TIGRFAM TIGR00800 ncs1: NCS1 nucleoside transporter family 26 447 8.7E-124 T 28-03-2018 IPR012681 Nucleobase cation symporter-1, NCS1 GO:0005215|GO:0006810|GO:0016020 CU254_RS26535 d12f2959388506b75592d62955307fc8 501 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 31 475 3.7E-132 T 28-03-2018 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 CU254_RS09685 d174e9cd47dcdf6ebb5ea82c38dcd095 461 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 354 458 2.6E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS09685 d174e9cd47dcdf6ebb5ea82c38dcd095 461 SMART SM00387 351 461 9.2E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS09685 d174e9cd47dcdf6ebb5ea82c38dcd095 461 PRINTS PR00344 Bacterial sensor protein C-terminal signature 421 439 2.1E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS09685 d174e9cd47dcdf6ebb5ea82c38dcd095 461 PRINTS PR00344 Bacterial sensor protein C-terminal signature 388 402 2.1E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS09685 d174e9cd47dcdf6ebb5ea82c38dcd095 461 SMART SM00304 184 241 1.6E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS09685 d174e9cd47dcdf6ebb5ea82c38dcd095 461 Gene3D G3DSA:3.30.450.20 23 153 2.2E-4 T 28-03-2018 CU254_RS09685 d174e9cd47dcdf6ebb5ea82c38dcd095 461 Gene3D G3DSA:3.30.565.10 309 461 1.2E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS09685 d174e9cd47dcdf6ebb5ea82c38dcd095 461 SUPERFAMILY SSF55874 297 459 1.24E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS09685 d174e9cd47dcdf6ebb5ea82c38dcd095 461 SUPERFAMILY SSF47384 226 306 4.9E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS09685 d174e9cd47dcdf6ebb5ea82c38dcd095 461 Gene3D G3DSA:1.10.287.130 232 303 1.0E-11 T 28-03-2018 CU254_RS09685 d174e9cd47dcdf6ebb5ea82c38dcd095 461 Pfam PF00512 His Kinase A (phospho-acceptor) domain 243 306 1.9E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS09685 d174e9cd47dcdf6ebb5ea82c38dcd095 461 SMART SM00388 242 307 3.0E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS34935 742fc4dc16b9b69fef84f62bd758e358 221 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 42 127 5.2E-23 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CU254_RS34935 742fc4dc16b9b69fef84f62bd758e358 221 SUPERFAMILY SSF50475 20 221 2.9E-66 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS34935 742fc4dc16b9b69fef84f62bd758e358 221 Gene3D G3DSA:2.30.110.10 18 221 8.8E-75 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS34935 742fc4dc16b9b69fef84f62bd758e358 221 Hamap MF_01629 Pyridoxine/pyridoxamine 5'-phosphate oxidase [pdxH]. 18 221 37.161 T 28-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CU254_RS34935 742fc4dc16b9b69fef84f62bd758e358 221 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 10 221 5.1E-75 T 28-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CU254_RS34935 742fc4dc16b9b69fef84f62bd758e358 221 ProSitePatterns PS01064 Pyridoxamine 5'-phosphate oxidase signature. 191 204 - T 28-03-2018 IPR019740 Pyridoxamine 5'-phosphate oxidase, conserved site GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CU254_RS34935 742fc4dc16b9b69fef84f62bd758e358 221 PIRSF PIRSF000190 7 221 1.1E-79 T 28-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CU254_RS34935 742fc4dc16b9b69fef84f62bd758e358 221 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 181 221 6.1E-18 T 28-03-2018 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CU254_RS15380 cb66f07a3fc3218aa3a0ad6764b20e4d 142 SUPERFAMILY SSF46785 10 140 6.19E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS15380 cb66f07a3fc3218aa3a0ad6764b20e4d 142 Gene3D G3DSA:1.10.10.10 3 142 2.8E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS15380 cb66f07a3fc3218aa3a0ad6764b20e4d 142 Pfam PF01047 MarR family 35 96 1.4E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS15380 cb66f07a3fc3218aa3a0ad6764b20e4d 142 SMART SM00347 28 129 6.1E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS15380 cb66f07a3fc3218aa3a0ad6764b20e4d 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 92 108 1.8E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS15380 cb66f07a3fc3218aa3a0ad6764b20e4d 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 73 88 1.8E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS00800 ad778b1e7b23448391405b76f3f3aa79 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 1.9E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS00800 ad778b1e7b23448391405b76f3f3aa79 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 1.9E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS00800 ad778b1e7b23448391405b76f3f3aa79 192 Gene3D G3DSA:1.10.10.60 51 122 3.1E-7 T 28-03-2018 CU254_RS00800 ad778b1e7b23448391405b76f3f3aa79 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 63 4.5E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS00800 ad778b1e7b23448391405b76f3f3aa79 192 Gene3D G3DSA:1.10.10.60 1 50 8.8E-16 T 28-03-2018 CU254_RS00800 ad778b1e7b23448391405b76f3f3aa79 192 SUPERFAMILY SSF46689 11 80 6.48E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS16515 fb0bc2929b8eb1e07aefa3cf45d9f15e 363 Gene3D G3DSA:3.30.420.60 116 245 2.9E-22 T 28-03-2018 CU254_RS16515 fb0bc2929b8eb1e07aefa3cf45d9f15e 363 Gene3D G3DSA:3.30.1330.30 248 363 3.4E-8 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CU254_RS17925 68d0cccc7165c7555ade329ff8a98a10 308 SUPERFAMILY SSF53850 92 300 2.48E-32 T 28-03-2018 CU254_RS17925 68d0cccc7165c7555ade329ff8a98a10 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 2.0E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS17925 68d0cccc7165c7555ade329ff8a98a10 308 Pfam PF03466 LysR substrate binding domain 91 296 3.0E-34 T 28-03-2018 IPR005119 LysR, substrate-binding CU254_RS17925 68d0cccc7165c7555ade329ff8a98a10 308 SUPERFAMILY SSF46785 4 88 1.61E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS17925 68d0cccc7165c7555ade329ff8a98a10 308 Gene3D G3DSA:3.40.190.10 181 267 1.3E-16 T 28-03-2018 CU254_RS17925 68d0cccc7165c7555ade329ff8a98a10 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 3.4E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS17925 68d0cccc7165c7555ade329ff8a98a10 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 3.4E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS17925 68d0cccc7165c7555ade329ff8a98a10 308 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 3.4E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS17925 68d0cccc7165c7555ade329ff8a98a10 308 Gene3D G3DSA:1.10.10.10 1 85 6.3E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS17925 68d0cccc7165c7555ade329ff8a98a10 308 Gene3D G3DSA:3.40.190.10 90 180 0.0014 T 28-03-2018 CU254_RS03810 46f19de8930c5daee22e4e7cf5c04c02 294 SMART SM00244 19 177 2.8E-59 T 28-03-2018 IPR001107 Band 7 domain CU254_RS03810 46f19de8930c5daee22e4e7cf5c04c02 294 Pfam PF01145 SPFH domain / Band 7 family 23 193 4.1E-32 T 28-03-2018 IPR001107 Band 7 domain CU254_RS03810 46f19de8930c5daee22e4e7cf5c04c02 294 SUPERFAMILY SSF117892 51 184 2.75E-40 T 28-03-2018 IPR001107 Band 7 domain CU254_RS03810 46f19de8930c5daee22e4e7cf5c04c02 294 PRINTS PR00721 Stomatin signature 172 193 2.6E-57 T 28-03-2018 IPR001972 Stomatin family GO:0016020 CU254_RS03810 46f19de8930c5daee22e4e7cf5c04c02 294 PRINTS PR00721 Stomatin signature 109 126 2.6E-57 T 28-03-2018 IPR001972 Stomatin family GO:0016020 CU254_RS03810 46f19de8930c5daee22e4e7cf5c04c02 294 PRINTS PR00721 Stomatin signature 197 220 2.6E-57 T 28-03-2018 IPR001972 Stomatin family GO:0016020 CU254_RS03810 46f19de8930c5daee22e4e7cf5c04c02 294 PRINTS PR00721 Stomatin signature 26 48 2.6E-57 T 28-03-2018 IPR001972 Stomatin family GO:0016020 CU254_RS03810 46f19de8930c5daee22e4e7cf5c04c02 294 PRINTS PR00721 Stomatin signature 153 171 2.6E-57 T 28-03-2018 IPR001972 Stomatin family GO:0016020 CU254_RS03810 46f19de8930c5daee22e4e7cf5c04c02 294 PRINTS PR00721 Stomatin signature 129 152 2.6E-57 T 28-03-2018 IPR001972 Stomatin family GO:0016020 CU254_RS03810 46f19de8930c5daee22e4e7cf5c04c02 294 PRINTS PR00721 Stomatin signature 74 95 2.6E-57 T 28-03-2018 IPR001972 Stomatin family GO:0016020 CU254_RS32055 6a6d22b67394ba113e39f956df0a828a 403 Gene3D G3DSA:3.40.47.10 1 278 5.6E-48 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS32055 6a6d22b67394ba113e39f956df0a828a 403 SUPERFAMILY SSF53901 3 275 1.35E-66 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS32055 6a6d22b67394ba113e39f956df0a828a 403 Gene3D G3DSA:3.40.47.10 279 403 5.1E-31 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS32055 6a6d22b67394ba113e39f956df0a828a 403 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 401 4.4E-131 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CU254_RS32055 6a6d22b67394ba113e39f956df0a828a 403 ProSitePatterns PS00737 Thiolases signature 2. 349 365 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CU254_RS32055 6a6d22b67394ba113e39f956df0a828a 403 SUPERFAMILY SSF53901 281 402 7.2E-44 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS32055 6a6d22b67394ba113e39f956df0a828a 403 Pfam PF00108 Thiolase, N-terminal domain 6 270 3.7E-49 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CU254_RS32055 6a6d22b67394ba113e39f956df0a828a 403 PIRSF PIRSF000429 2 403 1.1E-110 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CU254_RS32055 6a6d22b67394ba113e39f956df0a828a 403 ProSitePatterns PS00099 Thiolases active site. 384 397 - T 28-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CU254_RS32055 6a6d22b67394ba113e39f956df0a828a 403 Pfam PF02803 Thiolase, C-terminal domain 281 402 2.6E-45 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CU254_RS38795 9cedf00dcbb7b9110fc2b35b704f8c21 302 ProSitePatterns PS00211 ABC transporters family signature. 128 142 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS38795 9cedf00dcbb7b9110fc2b35b704f8c21 302 Gene3D G3DSA:3.40.50.300 1 256 1.1E-56 T 28-03-2018 CU254_RS38795 9cedf00dcbb7b9110fc2b35b704f8c21 302 SUPERFAMILY SSF52540 2 225 4.15E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS38795 9cedf00dcbb7b9110fc2b35b704f8c21 302 SMART SM00382 26 204 4.9E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS38795 9cedf00dcbb7b9110fc2b35b704f8c21 302 Pfam PF00005 ABC transporter 18 156 3.9E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS23075 9df693b3942cb61ae5d47938a37a3050 126 Gene3D G3DSA:2.102.10.10 2 126 6.0E-25 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CU254_RS23075 9df693b3942cb61ae5d47938a37a3050 126 SUPERFAMILY SSF50022 9 126 1.83E-23 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CU254_RS23075 9df693b3942cb61ae5d47938a37a3050 126 Pfam PF00355 Rieske [2Fe-2S] domain 9 107 6.3E-12 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CU254_RS35855 37013fb2a1eeb847651f7514dee32b05 373 SUPERFAMILY SSF47203 213 349 2.3E-7 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS35855 37013fb2a1eeb847651f7514dee32b05 373 SUPERFAMILY SSF56645 7 196 1.14E-23 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS35855 37013fb2a1eeb847651f7514dee32b05 373 PIRSF PIRSF016578 1 372 2.9E-92 T 28-03-2018 CU254_RS35855 37013fb2a1eeb847651f7514dee32b05 373 Gene3D G3DSA:1.10.540.10 4 88 1.0E-9 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS35855 37013fb2a1eeb847651f7514dee32b05 373 Gene3D G3DSA:1.20.140.10 190 348 5.9E-13 T 28-03-2018 CU254_RS35855 37013fb2a1eeb847651f7514dee32b05 373 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 85 1.7E-6 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS35855 37013fb2a1eeb847651f7514dee32b05 373 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 221 350 6.1E-16 T 28-03-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain CU254_RS35855 37013fb2a1eeb847651f7514dee32b05 373 Gene3D G3DSA:2.40.110.10 89 189 2.5E-11 T 28-03-2018 CU254_RS04730 9ad6876b7d8dfa36a7033409e42755af 132 SMART SM00226 4 129 4.3E-43 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CU254_RS04730 9ad6876b7d8dfa36a7033409e42755af 132 Gene3D G3DSA:3.40.50.2300 2 132 2.5E-35 T 28-03-2018 CU254_RS04730 9ad6876b7d8dfa36a7033409e42755af 132 SUPERFAMILY SSF52788 4 127 3.27E-35 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CU254_RS04730 9ad6876b7d8dfa36a7033409e42755af 132 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 6 127 2.1E-22 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CU254_RS29890 894b20e63e29cc33a2fb89c0d2fbc8d4 362 Pfam PF00535 Glycosyl transferase family 2 44 216 5.6E-23 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CU254_RS29890 894b20e63e29cc33a2fb89c0d2fbc8d4 362 TIGRFAM TIGR03469 HpnB: hopene-associated glycosyltransferase HpnB 4 362 1.4E-132 T 28-03-2018 IPR017832 Glycosyl transferase, family 2, hopene-associated, HpnB CU254_RS29890 894b20e63e29cc33a2fb89c0d2fbc8d4 362 Gene3D G3DSA:3.90.550.10 21 284 3.1E-42 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS29890 894b20e63e29cc33a2fb89c0d2fbc8d4 362 SUPERFAMILY SSF53448 29 268 2.39E-38 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS27940 1ba0bbd9ba933b99b8c05b9793eaa08f 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 9.7E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS27940 1ba0bbd9ba933b99b8c05b9793eaa08f 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 9.7E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS27940 1ba0bbd9ba933b99b8c05b9793eaa08f 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 9.7E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS27940 1ba0bbd9ba933b99b8c05b9793eaa08f 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 9.7E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS27940 1ba0bbd9ba933b99b8c05b9793eaa08f 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 9.7E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS27940 1ba0bbd9ba933b99b8c05b9793eaa08f 250 SUPERFAMILY SSF51735 2 233 1.28E-67 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS27940 1ba0bbd9ba933b99b8c05b9793eaa08f 250 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2 179 0.0012 T 28-03-2018 CU254_RS27940 1ba0bbd9ba933b99b8c05b9793eaa08f 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 2.1E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS27940 1ba0bbd9ba933b99b8c05b9793eaa08f 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 2.1E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS27940 1ba0bbd9ba933b99b8c05b9793eaa08f 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 128 136 2.1E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS27940 1ba0bbd9ba933b99b8c05b9793eaa08f 250 Pfam PF00106 short chain dehydrogenase 2 188 3.4E-59 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS27940 1ba0bbd9ba933b99b8c05b9793eaa08f 250 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 135 163 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS27940 1ba0bbd9ba933b99b8c05b9793eaa08f 250 Gene3D G3DSA:3.40.50.720 1 235 1.7E-61 T 28-03-2018 CU254_RS10850 9ed193c4e5d54ddf83e58cb6477814c9 476 Pfam PF04545 Sigma-70, region 4 411 464 1.4E-18 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS10850 9ed193c4e5d54ddf83e58cb6477814c9 476 Pfam PF04539 Sigma-70 region 3 322 397 1.5E-28 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS10850 9ed193c4e5d54ddf83e58cb6477814c9 476 Pfam PF04542 Sigma-70 region 2 243 312 1.7E-22 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS10850 9ed193c4e5d54ddf83e58cb6477814c9 476 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 239 475 7.5E-114 T 28-03-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 CU254_RS10850 9ed193c4e5d54ddf83e58cb6477814c9 476 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 30 476 32.887 T 28-03-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 CU254_RS10850 9ed193c4e5d54ddf83e58cb6477814c9 476 SUPERFAMILY SSF88659 316 389 1.14E-22 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS10850 9ed193c4e5d54ddf83e58cb6477814c9 476 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 267 280 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS10850 9ed193c4e5d54ddf83e58cb6477814c9 476 SUPERFAMILY SSF88659 375 475 2.62E-26 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS10850 9ed193c4e5d54ddf83e58cb6477814c9 476 Gene3D G3DSA:1.10.601.10 1 312 4.1E-84 T 28-03-2018 CU254_RS10850 9ed193c4e5d54ddf83e58cb6477814c9 476 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 436 462 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS10850 9ed193c4e5d54ddf83e58cb6477814c9 476 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 239 464 2.7E-35 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS10850 9ed193c4e5d54ddf83e58cb6477814c9 476 SUPERFAMILY SSF88946 171 313 1.13E-54 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS10850 9ed193c4e5d54ddf83e58cb6477814c9 476 Gene3D G3DSA:1.10.10.10 405 476 4.6E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS10850 9ed193c4e5d54ddf83e58cb6477814c9 476 PRINTS PR00046 Major sigma-70 factor signature 291 299 3.0E-29 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS10850 9ed193c4e5d54ddf83e58cb6477814c9 476 PRINTS PR00046 Major sigma-70 factor signature 267 280 3.0E-29 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS10850 9ed193c4e5d54ddf83e58cb6477814c9 476 PRINTS PR00046 Major sigma-70 factor signature 451 462 3.0E-29 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS10850 9ed193c4e5d54ddf83e58cb6477814c9 476 PRINTS PR00046 Major sigma-70 factor signature 415 427 3.0E-29 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS10850 9ed193c4e5d54ddf83e58cb6477814c9 476 PRINTS PR00046 Major sigma-70 factor signature 436 451 3.0E-29 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS10850 9ed193c4e5d54ddf83e58cb6477814c9 476 Pfam PF00140 Sigma-70 factor, region 1.2 174 207 4.1E-16 T 28-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS10850 9ed193c4e5d54ddf83e58cb6477814c9 476 Gene3D G3DSA:1.10.10.10 313 363 1.2E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS37625 f7c0daa8abfba68380deceb66aa08c2d 268 SMART SM00641 64 173 1.7E-36 T 28-03-2018 IPR018077 Glycoside hydrolase, family 25 subgroup CU254_RS37625 f7c0daa8abfba68380deceb66aa08c2d 268 SUPERFAMILY SSF51445 64 265 5.0E-62 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS37625 f7c0daa8abfba68380deceb66aa08c2d 268 Pfam PF01183 Glycosyl hydrolases family 25 68 250 1.0E-45 T 28-03-2018 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 CU254_RS37625 f7c0daa8abfba68380deceb66aa08c2d 268 Gene3D G3DSA:3.20.20.80 53 267 2.2E-63 T 28-03-2018 CU254_RS37545 7d95efadfe342e4177f20e2b11edbbb9 286 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 7 186 2.8E-57 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CU254_RS37545 7d95efadfe342e4177f20e2b11edbbb9 286 Gene3D G3DSA:1.10.1040.10 188 286 2.0E-32 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CU254_RS37545 7d95efadfe342e4177f20e2b11edbbb9 286 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 189 285 1.1E-30 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CU254_RS37545 7d95efadfe342e4177f20e2b11edbbb9 286 SUPERFAMILY SSF51735 4 186 1.06E-50 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS37545 7d95efadfe342e4177f20e2b11edbbb9 286 Gene3D G3DSA:3.40.50.720 1 187 1.2E-50 T 28-03-2018 CU254_RS37545 7d95efadfe342e4177f20e2b11edbbb9 286 PIRSF PIRSF000105 2 286 2.7E-79 T 28-03-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 CU254_RS37545 7d95efadfe342e4177f20e2b11edbbb9 286 SUPERFAMILY SSF48179 189 286 2.89E-29 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CU254_RS10390 37764f632e1de5252f89eec918b0730a 390 SUPERFAMILY SSF47203 228 386 2.58E-20 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS10390 37764f632e1de5252f89eec918b0730a 390 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 209 4.5E-20 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CU254_RS10390 37764f632e1de5252f89eec918b0730a 390 Gene3D G3DSA:1.20.140.10 216 389 1.1E-30 T 28-03-2018 CU254_RS10390 37764f632e1de5252f89eec918b0730a 390 Gene3D G3DSA:1.10.540.10 1 119 4.9E-27 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS10390 37764f632e1de5252f89eec918b0730a 390 SUPERFAMILY SSF56645 3 241 1.05E-70 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS10390 37764f632e1de5252f89eec918b0730a 390 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 228 381 1.8E-25 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS10390 37764f632e1de5252f89eec918b0730a 390 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 118 7.3E-22 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS10390 37764f632e1de5252f89eec918b0730a 390 Gene3D G3DSA:2.40.110.10 120 215 1.5E-33 T 28-03-2018 CU254_RS30800 760fb9d32278251f215eb5f9158be807 524 Gene3D G3DSA:3.20.20.60 259 293 2.4E-10 T 28-03-2018 CU254_RS30800 760fb9d32278251f215eb5f9158be807 524 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 418 436 - T 28-03-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 CU254_RS30800 760fb9d32278251f215eb5f9158be807 524 Gene3D G3DSA:1.10.274.10 24 140 1.3E-18 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CU254_RS30800 760fb9d32278251f215eb5f9158be807 524 SUPERFAMILY SSF52009 120 223 1.05E-26 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CU254_RS30800 760fb9d32278251f215eb5f9158be807 524 Gene3D G3DSA:3.20.20.60 294 514 9.5E-68 T 28-03-2018 CU254_RS30800 760fb9d32278251f215eb5f9158be807 524 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 418 433 5.1E-14 T 28-03-2018 CU254_RS30800 760fb9d32278251f215eb5f9158be807 524 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 274 293 5.1E-14 T 28-03-2018 CU254_RS30800 760fb9d32278251f215eb5f9158be807 524 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 471 483 5.1E-14 T 28-03-2018 CU254_RS30800 760fb9d32278251f215eb5f9158be807 524 Gene3D G3DSA:3.50.30.10 143 258 1.2E-23 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CU254_RS30800 760fb9d32278251f215eb5f9158be807 524 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 179 190 - T 28-03-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 CU254_RS30800 760fb9d32278251f215eb5f9158be807 524 PIRSF PIRSF000732 1 524 4.3E-143 T 28-03-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 CU254_RS30800 760fb9d32278251f215eb5f9158be807 524 Pfam PF00391 PEP-utilising enzyme, mobile domain 148 218 4.6E-20 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CU254_RS30800 760fb9d32278251f215eb5f9158be807 524 Pfam PF05524 PEP-utilising enzyme, N-terminal 5 121 1.5E-17 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CU254_RS30800 760fb9d32278251f215eb5f9158be807 524 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 244 511 9.8E-78 T 28-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 CU254_RS30800 760fb9d32278251f215eb5f9158be807 524 SUPERFAMILY SSF51621 242 520 4.71E-83 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CU254_RS30800 760fb9d32278251f215eb5f9158be807 524 SUPERFAMILY SSF47831 27 138 1.7E-17 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CU254_RS13910 54a20ba4a6bc2e85c32dd9c40fcdc96b 487 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 184 461 5.1E-90 T 28-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 CU254_RS13910 54a20ba4a6bc2e85c32dd9c40fcdc96b 487 Gene3D G3DSA:3.40.50.1580 14 178 1.3E-19 T 28-03-2018 CU254_RS13910 54a20ba4a6bc2e85c32dd9c40fcdc96b 487 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 182 464 35.194 T 28-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 CU254_RS13910 54a20ba4a6bc2e85c32dd9c40fcdc96b 487 Gene3D G3DSA:3.40.50.2300 179 465 2.7E-5 T 28-03-2018 CU254_RS13910 54a20ba4a6bc2e85c32dd9c40fcdc96b 487 Pfam PF01048 Phosphorylase superfamily 22 147 6.3E-8 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CU254_RS13910 54a20ba4a6bc2e85c32dd9c40fcdc96b 487 SUPERFAMILY SSF53167 22 147 1.96E-19 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CU254_RS13910 54a20ba4a6bc2e85c32dd9c40fcdc96b 487 Pfam PF02401 LytB protein 184 460 2.9E-85 T 28-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 CU254_RS05605 a36c5aae8153964761273a50e7fb7f67 270 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 225 240 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CU254_RS05605 a36c5aae8153964761273a50e7fb7f67 270 SUPERFAMILY SSF51430 3 264 3.27E-98 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS05605 a36c5aae8153964761273a50e7fb7f67 270 PIRSF PIRSF000097 108 267 1.1E-46 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CU254_RS05605 a36c5aae8153964761273a50e7fb7f67 270 PIRSF PIRSF000097 1 113 3.8E-41 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CU254_RS05605 a36c5aae8153964761273a50e7fb7f67 270 PRINTS PR00069 Aldo-keto reductase signature 121 138 2.1E-47 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CU254_RS05605 a36c5aae8153964761273a50e7fb7f67 270 PRINTS PR00069 Aldo-keto reductase signature 33 57 2.1E-47 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CU254_RS05605 a36c5aae8153964761273a50e7fb7f67 270 PRINTS PR00069 Aldo-keto reductase signature 89 107 2.1E-47 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CU254_RS05605 a36c5aae8153964761273a50e7fb7f67 270 PRINTS PR00069 Aldo-keto reductase signature 155 184 2.1E-47 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CU254_RS05605 a36c5aae8153964761273a50e7fb7f67 270 PRINTS PR00069 Aldo-keto reductase signature 192 216 2.1E-47 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CU254_RS05605 a36c5aae8153964761273a50e7fb7f67 270 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 37 54 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CU254_RS05605 a36c5aae8153964761273a50e7fb7f67 270 Gene3D G3DSA:3.20.20.100 1 270 4.4E-100 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS05605 a36c5aae8153964761273a50e7fb7f67 270 Pfam PF00248 Aldo/keto reductase family 20 255 2.7E-51 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS23040 37c314aaa6d2be8995925d06e5af14e1 145 Pfam PF03928 Haem-degrading 18 135 3.8E-24 T 28-03-2018 IPR005624 Haem-degrading CU254_RS23040 37c314aaa6d2be8995925d06e5af14e1 145 SUPERFAMILY SSF143744 17 137 1.1E-27 T 28-03-2018 CU254_RS35265 87b5999c96d388cfcfb613d489e316d9 332 Pfam PF05331 Protein of unknown function (DUF742) 221 332 7.7E-32 T 28-03-2018 IPR007995 Protein of unknown function DUF742 CU254_RS02210 2c7369bdfecf9a8026c90f983bccfa5f 445 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 373 438 6.5E-13 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CU254_RS02210 2c7369bdfecf9a8026c90f983bccfa5f 445 Gene3D G3DSA:3.40.120.10 1 142 2.0E-45 T 28-03-2018 CU254_RS02210 2c7369bdfecf9a8026c90f983bccfa5f 445 Gene3D G3DSA:3.40.120.10 156 268 7.1E-32 T 28-03-2018 CU254_RS02210 2c7369bdfecf9a8026c90f983bccfa5f 445 Gene3D G3DSA:3.40.120.10 269 373 2.7E-32 T 28-03-2018 CU254_RS02210 2c7369bdfecf9a8026c90f983bccfa5f 445 SUPERFAMILY SSF55957 357 443 3.27E-21 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CU254_RS02210 2c7369bdfecf9a8026c90f983bccfa5f 445 Gene3D G3DSA:3.30.310.50 374 444 5.8E-19 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CU254_RS02210 2c7369bdfecf9a8026c90f983bccfa5f 445 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 257 367 1.4E-32 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CU254_RS02210 2c7369bdfecf9a8026c90f983bccfa5f 445 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 442 2.3E-179 T 28-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CU254_RS02210 2c7369bdfecf9a8026c90f983bccfa5f 445 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 96 105 - T 28-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CU254_RS02210 2c7369bdfecf9a8026c90f983bccfa5f 445 SUPERFAMILY SSF53738 4 180 3.85E-47 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CU254_RS02210 2c7369bdfecf9a8026c90f983bccfa5f 445 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 158 253 4.2E-18 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CU254_RS02210 2c7369bdfecf9a8026c90f983bccfa5f 445 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 233 248 1.9E-12 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CU254_RS02210 2c7369bdfecf9a8026c90f983bccfa5f 445 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 95 109 1.9E-12 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CU254_RS02210 2c7369bdfecf9a8026c90f983bccfa5f 445 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 173 192 1.9E-12 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CU254_RS02210 2c7369bdfecf9a8026c90f983bccfa5f 445 SUPERFAMILY SSF53738 156 255 7.06E-28 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CU254_RS02210 2c7369bdfecf9a8026c90f983bccfa5f 445 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 134 2.1E-40 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CU254_RS02210 2c7369bdfecf9a8026c90f983bccfa5f 445 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 444 44.24 T 28-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CU254_RS02210 2c7369bdfecf9a8026c90f983bccfa5f 445 SUPERFAMILY SSF53738 257 364 2.28E-30 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CU254_RS06940 9c794ec79e9e55de9f4af8ef3bd98653 262 SUPERFAMILY SSF52540 3 224 6.82E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS06940 9c794ec79e9e55de9f4af8ef3bd98653 262 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS06940 9c794ec79e9e55de9f4af8ef3bd98653 262 Gene3D G3DSA:3.40.50.300 1 227 7.3E-62 T 28-03-2018 CU254_RS06940 9c794ec79e9e55de9f4af8ef3bd98653 262 Pfam PF00005 ABC transporter 19 167 7.1E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS06940 9c794ec79e9e55de9f4af8ef3bd98653 262 SMART SM00382 27 211 1.2E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS25465 08427e2745d46febe75b0270f0597dce 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 2.2E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS25465 08427e2745d46febe75b0270f0597dce 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 2.2E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS25465 08427e2745d46febe75b0270f0597dce 197 Gene3D G3DSA:1.10.260.40 38 65 3.9E-13 T 28-03-2018 CU254_RS25465 08427e2745d46febe75b0270f0597dce 197 Gene3D G3DSA:1.10.357.10 66 191 2.4E-7 T 28-03-2018 CU254_RS25465 08427e2745d46febe75b0270f0597dce 197 Gene3D G3DSA:1.10.10.60 1 37 2.2E-17 T 28-03-2018 CU254_RS25465 08427e2745d46febe75b0270f0597dce 197 SUPERFAMILY SSF46689 1 73 1.42E-19 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS25465 08427e2745d46febe75b0270f0597dce 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 1.5E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS30635 6e2821e9a88d9c28ecfc60cf5c9a733d 274 SUPERFAMILY SSF46894 196 271 1.46E-20 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS30635 6e2821e9a88d9c28ecfc60cf5c9a733d 274 ProSitePatterns PS00622 LuxR-type HTH domain signature. 225 252 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS30635 6e2821e9a88d9c28ecfc60cf5c9a733d 274 SUPERFAMILY SSF55781 50 151 1.91E-6 T 28-03-2018 IPR029016 GAF domain-like CU254_RS30635 6e2821e9a88d9c28ecfc60cf5c9a733d 274 Gene3D G3DSA:3.30.450.40 8 153 5.0E-9 T 28-03-2018 IPR029016 GAF domain-like CU254_RS30635 6e2821e9a88d9c28ecfc60cf5c9a733d 274 Gene3D G3DSA:1.10.10.10 184 270 7.7E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS30635 6e2821e9a88d9c28ecfc60cf5c9a733d 274 SMART SM00421 208 265 5.9E-23 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS30635 6e2821e9a88d9c28ecfc60cf5c9a733d 274 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 241 253 3.1E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS30635 6e2821e9a88d9c28ecfc60cf5c9a733d 274 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 211 225 3.1E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS30635 6e2821e9a88d9c28ecfc60cf5c9a733d 274 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 225 241 3.1E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS30635 6e2821e9a88d9c28ecfc60cf5c9a733d 274 Pfam PF00196 Bacterial regulatory proteins, luxR family 210 265 1.2E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS07305 3d594b731b168065b4b93de418b624e2 184 PIRSF PIRSF004553 1 180 1.5E-51 T 28-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 CU254_RS07305 3d594b731b168065b4b93de418b624e2 184 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 111 117 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CU254_RS07305 3d594b731b168065b4b93de418b624e2 184 SUPERFAMILY SSF53335 2 174 1.86E-38 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS07305 3d594b731b168065b4b93de418b624e2 184 Gene3D G3DSA:3.40.50.150 1 183 1.3E-31 T 28-03-2018 CU254_RS07305 3d594b731b168065b4b93de418b624e2 184 Pfam PF03602 Conserved hypothetical protein 95 1 174 7.1E-47 T 28-03-2018 CU254_RS07305 3d594b731b168065b4b93de418b624e2 184 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 2 176 4.3E-45 T 28-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 CU254_RS14540 3e59cf01153e46af6587d19b584c97e0 193 SUPERFAMILY SSF103088 86 178 5.36E-11 T 28-03-2018 IPR006665 OmpA-like domain CU254_RS14540 3e59cf01153e46af6587d19b584c97e0 193 Pfam PF00691 OmpA family 101 181 8.4E-15 T 28-03-2018 IPR006665 OmpA-like domain CU254_RS14540 3e59cf01153e46af6587d19b584c97e0 193 Gene3D G3DSA:3.30.1330.60 73 188 1.1E-15 T 28-03-2018 IPR006665 OmpA-like domain CU254_RS02825 9a5065ffaa057693ad84b5d372fc3836 521 SUPERFAMILY SSF52540 16 238 1.02E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS02825 9a5065ffaa057693ad84b5d372fc3836 521 Gene3D G3DSA:3.40.50.300 262 517 2.3E-30 T 28-03-2018 CU254_RS02825 9a5065ffaa057693ad84b5d372fc3836 521 SMART SM00382 41 226 1.5E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS02825 9a5065ffaa057693ad84b5d372fc3836 521 SMART SM00382 292 493 17.0 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS02825 9a5065ffaa057693ad84b5d372fc3836 521 ProSitePatterns PS00211 ABC transporters family signature. 417 431 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS02825 9a5065ffaa057693ad84b5d372fc3836 521 SUPERFAMILY SSF52540 261 504 1.1E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS02825 9a5065ffaa057693ad84b5d372fc3836 521 Pfam PF00005 ABC transporter 34 178 7.2E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS02825 9a5065ffaa057693ad84b5d372fc3836 521 Pfam PF00005 ABC transporter 283 444 4.3E-11 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS02825 9a5065ffaa057693ad84b5d372fc3836 521 Gene3D G3DSA:3.40.50.300 3 245 2.1E-52 T 28-03-2018 CU254_RS32755 a4d06d143d4f1181b2b10369d1700e27 987 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 31 44 - T 28-03-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 CU254_RS32755 a4d06d143d4f1181b2b10369d1700e27 987 Pfam PF13476 AAA domain 6 225 2.5E-25 T 28-03-2018 CU254_RS32755 a4d06d143d4f1181b2b10369d1700e27 987 SUPERFAMILY SSF52540 764 981 1.48E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS32755 a4d06d143d4f1181b2b10369d1700e27 987 SUPERFAMILY SSF52540 6 225 1.48E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS32755 a4d06d143d4f1181b2b10369d1700e27 987 Pfam PF13558 Putative exonuclease SbcCD, C subunit 883 945 2.3E-11 T 28-03-2018 CU254_RS32755 a4d06d143d4f1181b2b10369d1700e27 987 Gene3D G3DSA:3.40.50.300 1 197 6.0E-20 T 28-03-2018 CU254_RS32755 a4d06d143d4f1181b2b10369d1700e27 987 Gene3D G3DSA:1.20.5.50 520 654 1.3E-4 T 28-03-2018 CU254_RS32755 a4d06d143d4f1181b2b10369d1700e27 987 Gene3D G3DSA:3.40.50.300 684 981 7.2E-5 T 28-03-2018 CU254_RS00375 4ce5cd5c33819ff1abec3275a8c7a689 283 SUPERFAMILY SSF51197 1 253 1.33E-42 T 28-03-2018 CU254_RS00375 4ce5cd5c33819ff1abec3275a8c7a689 283 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 13 254 3.0E-34 T 28-03-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 CU254_RS00375 4ce5cd5c33819ff1abec3275a8c7a689 283 Gene3D G3DSA:3.60.130.10 1 266 1.8E-42 T 28-03-2018 CU254_RS00050 f53e3d3c080718b647391f573b85e769 668 SUPERFAMILY SSF51905 554 636 3.33E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS00050 f53e3d3c080718b647391f573b85e769 668 SUPERFAMILY SSF51905 461 519 3.33E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS00050 f53e3d3c080718b647391f573b85e769 668 SUPERFAMILY SSF51971 334 517 4.36E-40 T 28-03-2018 CU254_RS00050 f53e3d3c080718b647391f573b85e769 668 PRINTS PR00419 Adrenodoxin reductase family signature 400 413 6.5E-8 T 28-03-2018 CU254_RS00050 f53e3d3c080718b647391f573b85e769 668 PRINTS PR00419 Adrenodoxin reductase family signature 377 399 6.5E-8 T 28-03-2018 CU254_RS00050 f53e3d3c080718b647391f573b85e769 668 Gene3D G3DSA:3.20.20.70 3 370 2.3E-106 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS00050 f53e3d3c080718b647391f573b85e769 668 Gene3D G3DSA:3.50.50.60 485 623 1.4E-35 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS00050 f53e3d3c080718b647391f573b85e769 668 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 376 635 8.9E-25 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS00050 f53e3d3c080718b647391f573b85e769 668 SUPERFAMILY SSF51395 4 362 1.24E-105 T 28-03-2018 CU254_RS00050 f53e3d3c080718b647391f573b85e769 668 Gene3D G3DSA:3.50.50.60 376 484 2.3E-24 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS00050 f53e3d3c080718b647391f573b85e769 668 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 7 332 1.3E-78 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CU254_RS26785 97357bb7ca4dd32363afd21d3f098452 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 64 8.5E-19 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS26785 97357bb7ca4dd32363afd21d3f098452 208 Gene3D G3DSA:1.10.357.10 66 202 1.8E-19 T 28-03-2018 CU254_RS26785 97357bb7ca4dd32363afd21d3f098452 208 Gene3D G3DSA:1.10.10.60 2 65 1.9E-21 T 28-03-2018 CU254_RS26785 97357bb7ca4dd32363afd21d3f098452 208 ProSitePatterns PS01081 TetR-type HTH domain signature. 34 64 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CU254_RS26785 97357bb7ca4dd32363afd21d3f098452 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 6.9E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS26785 97357bb7ca4dd32363afd21d3f098452 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 6.9E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS26785 97357bb7ca4dd32363afd21d3f098452 208 SUPERFAMILY SSF48498 90 194 6.95E-11 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS26785 97357bb7ca4dd32363afd21d3f098452 208 SUPERFAMILY SSF46689 10 89 4.31E-21 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS20295 6243f51ee3545cd7d7e55667eb0fc3a8 81 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 26 77 3.0E-19 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS20295 6243f51ee3545cd7d7e55667eb0fc3a8 81 SUPERFAMILY SSF46911 3 76 1.57E-26 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS20295 6243f51ee3545cd7d7e55667eb0fc3a8 81 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 8 78 19.108 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS20295 6243f51ee3545cd7d7e55667eb0fc3a8 81 PRINTS PR00974 Ribosomal protein S18 family signature 33 43 1.8E-17 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS20295 6243f51ee3545cd7d7e55667eb0fc3a8 81 PRINTS PR00974 Ribosomal protein S18 family signature 43 50 1.8E-17 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS20295 6243f51ee3545cd7d7e55667eb0fc3a8 81 PRINTS PR00974 Ribosomal protein S18 family signature 65 75 1.8E-17 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS20295 6243f51ee3545cd7d7e55667eb0fc3a8 81 PRINTS PR00974 Ribosomal protein S18 family signature 51 65 1.8E-17 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS20295 6243f51ee3545cd7d7e55667eb0fc3a8 81 TIGRFAM TIGR00165 S18: ribosomal protein bS18 12 75 5.2E-24 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS20295 6243f51ee3545cd7d7e55667eb0fc3a8 81 Gene3D G3DSA:4.10.640.10 1 81 3.3E-30 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS20295 6243f51ee3545cd7d7e55667eb0fc3a8 81 Pfam PF01084 Ribosomal protein S18 24 73 4.7E-24 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS15295 a2a4a9a32ff17f5dcdd3a6fdce41b604 505 SUPERFAMILY SSF56801 21 503 2.35E-114 T 28-03-2018 CU254_RS15295 a2a4a9a32ff17f5dcdd3a6fdce41b604 505 Gene3D G3DSA:3.30.300.30 401 504 6.7E-28 T 28-03-2018 CU254_RS15295 a2a4a9a32ff17f5dcdd3a6fdce41b604 505 Pfam PF00501 AMP-binding enzyme 22 407 2.3E-66 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS15295 a2a4a9a32ff17f5dcdd3a6fdce41b604 505 Gene3D G3DSA:2.30.38.10 318 400 8.8E-19 T 28-03-2018 CU254_RS15295 a2a4a9a32ff17f5dcdd3a6fdce41b604 505 Gene3D G3DSA:3.40.50.980 168 317 1.3E-25 T 28-03-2018 CU254_RS15295 a2a4a9a32ff17f5dcdd3a6fdce41b604 505 Pfam PF13193 AMP-binding enzyme C-terminal domain 416 491 2.9E-18 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS15295 a2a4a9a32ff17f5dcdd3a6fdce41b604 505 Gene3D G3DSA:3.40.50.980 3 167 1.2E-29 T 28-03-2018 CU254_RS15295 a2a4a9a32ff17f5dcdd3a6fdce41b604 505 ProSitePatterns PS00455 Putative AMP-binding domain signature. 162 173 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS21090 97e85f656ae4fbd4687174fe1bfb9b67 232 Gene3D G3DSA:1.20.910.10 1 232 5.6E-32 T 28-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CU254_RS21090 97e85f656ae4fbd4687174fe1bfb9b67 232 TIGRFAM TIGR02111 PQQ_syn_pqqC: coenzyme PQQ biosynthesis protein C 7 228 1.2E-83 T 28-03-2018 IPR011845 Coenzyme PQQ biosynthesis protein C GO:0018189|GO:0055114 MetaCyc: PWY-6420 CU254_RS21090 97e85f656ae4fbd4687174fe1bfb9b67 232 Hamap MF_00654 Pyrroloquinoline-quinone synthase [pqqC]. 1 232 95.496 T 28-03-2018 IPR011845 Coenzyme PQQ biosynthesis protein C GO:0018189|GO:0055114 MetaCyc: PWY-6420 CU254_RS21090 97e85f656ae4fbd4687174fe1bfb9b67 232 Pfam PF03070 TENA/THI-4/PQQC family 16 223 1.9E-42 T 28-03-2018 IPR004305 Thiaminase-2/PQQC CU254_RS21090 97e85f656ae4fbd4687174fe1bfb9b67 232 SUPERFAMILY SSF48613 4 229 1.66E-58 T 28-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CU254_RS01155 6bae6825869c6e4390e4b77d28fb4707 510 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 14 28 - T 28-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CU254_RS01155 6bae6825869c6e4390e4b77d28fb4707 510 Gene3D G3DSA:3.40.1010.10 8 131 9.9E-25 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CU254_RS01155 6bae6825869c6e4390e4b77d28fb4707 510 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 10 203 1.5E-33 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CU254_RS01155 6bae6825869c6e4390e4b77d28fb4707 510 Pfam PF02602 Uroporphyrinogen-III synthase HemD 252 482 1.2E-64 T 28-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CU254_RS01155 6bae6825869c6e4390e4b77d28fb4707 510 SUPERFAMILY SSF69618 238 489 2.88E-70 T 28-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CU254_RS01155 6bae6825869c6e4390e4b77d28fb4707 510 SUPERFAMILY SSF53790 6 241 8.9E-41 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CU254_RS01155 6bae6825869c6e4390e4b77d28fb4707 510 Gene3D G3DSA:3.30.950.10 132 235 6.9E-4 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CU254_RS01155 6bae6825869c6e4390e4b77d28fb4707 510 Gene3D G3DSA:3.40.50.10090 399 493 3.5E-23 T 28-03-2018 CU254_RS01155 6bae6825869c6e4390e4b77d28fb4707 510 Gene3D G3DSA:3.40.50.10090 270 398 1.4E-30 T 28-03-2018 CU254_RS04105 f2b62f982607ae17dac54df784f45ca1 360 Gene3D G3DSA:3.30.70.1450 276 360 0.25 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CU254_RS04105 f2b62f982607ae17dac54df784f45ca1 360 SUPERFAMILY SSF81324 26 168 5.76E-20 T 28-03-2018 CU254_RS04105 f2b62f982607ae17dac54df784f45ca1 360 Gene3D G3DSA:1.10.287.70 34 136 4.1E-15 T 28-03-2018 CU254_RS04105 f2b62f982607ae17dac54df784f45ca1 360 Pfam PF07885 Ion channel 49 127 1.3E-12 T 28-03-2018 IPR013099 Potassium channel domain CU254_RS04105 f2b62f982607ae17dac54df784f45ca1 360 Pfam PF02254 TrkA-N domain 148 265 2.5E-26 T 28-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CU254_RS04105 f2b62f982607ae17dac54df784f45ca1 360 SUPERFAMILY SSF51735 143 288 3.2E-28 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS04105 f2b62f982607ae17dac54df784f45ca1 360 Gene3D G3DSA:3.40.50.720 137 265 7.3E-27 T 28-03-2018 CU254_RS07680 8016787a4be72a5f2abdf4fd4f723b87 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 69 1.8E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS07680 8016787a4be72a5f2abdf4fd4f723b87 198 Pfam PF16859 Bacterial transcriptional repressor C-terminal 86 192 9.1E-21 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS07680 8016787a4be72a5f2abdf4fd4f723b87 198 SUPERFAMILY SSF46689 16 74 9.93E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS07680 8016787a4be72a5f2abdf4fd4f723b87 198 Gene3D G3DSA:1.10.357.10 88 196 4.3E-11 T 28-03-2018 CU254_RS07680 8016787a4be72a5f2abdf4fd4f723b87 198 Gene3D G3DSA:1.10.10.60 2 46 7.5E-15 T 28-03-2018 CU254_RS07680 8016787a4be72a5f2abdf4fd4f723b87 198 SUPERFAMILY SSF48498 88 196 2.67E-17 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS07680 8016787a4be72a5f2abdf4fd4f723b87 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 2.3E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS07680 8016787a4be72a5f2abdf4fd4f723b87 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 2.3E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS07680 8016787a4be72a5f2abdf4fd4f723b87 198 Gene3D G3DSA:1.10.260.40 47 87 2.1E-13 T 28-03-2018 CU254_RS11115 61a133583f560574cfd827891c1322b1 294 Gene3D G3DSA:1.10.10.10 43 212 3.3E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS11115 61a133583f560574cfd827891c1322b1 294 TIGRFAM TIGR04222 near_uncomplex: TIGR04222 domain 12 204 4.0E-14 T 28-03-2018 IPR026467 Ser/Gly rich, Cys interspersed, C-terminal domain CU254_RS21035 c804caf10180e88f42ec7322294c9b74 855 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 336 342 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CU254_RS21035 c804caf10180e88f42ec7322294c9b74 855 SUPERFAMILY SSF81653 130 232 1.44E-23 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CU254_RS21035 c804caf10180e88f42ec7322294c9b74 855 SUPERFAMILY SSF81665 235 328 1.44E-80 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CU254_RS21035 c804caf10180e88f42ec7322294c9b74 855 SUPERFAMILY SSF81665 18 118 1.44E-80 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CU254_RS21035 c804caf10180e88f42ec7322294c9b74 855 SUPERFAMILY SSF81665 650 851 1.44E-80 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CU254_RS21035 c804caf10180e88f42ec7322294c9b74 855 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 89 359 1.0E-30 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CU254_RS21035 c804caf10180e88f42ec7322294c9b74 855 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 568 689 1.5E-25 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CU254_RS21035 c804caf10180e88f42ec7322294c9b74 855 Gene3D G3DSA:2.70.150.10 7 237 3.3E-34 T 28-03-2018 CU254_RS21035 c804caf10180e88f42ec7322294c9b74 855 PRINTS PR01836 Magnesium-transporting ATPase signature 709 722 6.8E-57 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CU254_RS21035 c804caf10180e88f42ec7322294c9b74 855 PRINTS PR01836 Magnesium-transporting ATPase signature 729 745 6.8E-57 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CU254_RS21035 c804caf10180e88f42ec7322294c9b74 855 PRINTS PR01836 Magnesium-transporting ATPase signature 762 783 6.8E-57 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CU254_RS21035 c804caf10180e88f42ec7322294c9b74 855 PRINTS PR01836 Magnesium-transporting ATPase signature 677 688 6.8E-57 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CU254_RS21035 c804caf10180e88f42ec7322294c9b74 855 PRINTS PR01836 Magnesium-transporting ATPase signature 247 263 6.8E-57 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CU254_RS21035 c804caf10180e88f42ec7322294c9b74 855 PRINTS PR01836 Magnesium-transporting ATPase signature 659 674 6.8E-57 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CU254_RS21035 c804caf10180e88f42ec7322294c9b74 855 PRINTS PR01836 Magnesium-transporting ATPase signature 809 830 6.8E-57 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CU254_RS21035 c804caf10180e88f42ec7322294c9b74 855 PRINTS PR01836 Magnesium-transporting ATPase signature 264 283 6.8E-57 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CU254_RS21035 c804caf10180e88f42ec7322294c9b74 855 Pfam PF00702 haloacid dehalogenase-like hydrolase 330 615 6.9E-18 T 28-03-2018 CU254_RS21035 c804caf10180e88f42ec7322294c9b74 855 SMART SM00831 9 80 2.2E-4 T 28-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 CU254_RS21035 c804caf10180e88f42ec7322294c9b74 855 Gene3D G3DSA:3.40.50.1000 503 627 2.2E-35 T 28-03-2018 IPR023214 HAD-like domain CU254_RS21035 c804caf10180e88f42ec7322294c9b74 855 Pfam PF00689 Cation transporting ATPase, C-terminus 685 845 1.2E-12 T 28-03-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 CU254_RS21035 c804caf10180e88f42ec7322294c9b74 855 Gene3D G3DSA:1.20.1110.10 628 852 1.8E-29 T 28-03-2018 CU254_RS21035 c804caf10180e88f42ec7322294c9b74 855 Pfam PF00122 E1-E2 ATPase 132 314 1.7E-39 T 28-03-2018 CU254_RS21035 c804caf10180e88f42ec7322294c9b74 855 Gene3D G3DSA:3.40.1110.10 265 502 1.4E-35 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CU254_RS21035 c804caf10180e88f42ec7322294c9b74 855 SUPERFAMILY SSF56784 332 352 1.5E-37 T 28-03-2018 IPR023214 HAD-like domain CU254_RS21035 c804caf10180e88f42ec7322294c9b74 855 SUPERFAMILY SSF56784 457 700 1.5E-37 T 28-03-2018 IPR023214 HAD-like domain CU254_RS21035 c804caf10180e88f42ec7322294c9b74 855 Pfam PF00690 Cation transporter/ATPase, N-terminus 14 74 7.4E-9 T 28-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 CU254_RS21035 c804caf10180e88f42ec7322294c9b74 855 TIGRFAM TIGR01524 ATPase-IIIB_Mg: magnesium-translocating P-type ATPase 16 855 2.2E-284 T 28-03-2018 IPR006415 P-type ATPase, subfamily IIIB GO:0015444|GO:0015693|GO:0016021 CU254_RS32665 52c1c60a03170d0106700daf0620399b 99 Pfam PF03795 YCII-related domain 1 81 5.7E-10 T 28-03-2018 IPR005545 YCII-related CU254_RS32665 52c1c60a03170d0106700daf0620399b 99 Gene3D G3DSA:3.30.70.1060 1 84 1.3E-14 T 28-03-2018 CU254_RS32665 52c1c60a03170d0106700daf0620399b 99 SUPERFAMILY SSF54909 1 83 1.15E-14 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS29265 9e43090e9914a9a6feac46d30cc18204 215 SUPERFAMILY SSF89562 14 173 2.35E-39 T 28-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CU254_RS29265 9e43090e9914a9a6feac46d30cc18204 215 Gene3D G3DSA:3.50.30.40 9 183 2.2E-47 T 28-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CU254_RS29265 9e43090e9914a9a6feac46d30cc18204 215 Pfam PF03737 Aldolase/RraA 31 163 1.1E-34 T 28-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CU254_RS36035 5f45a92317da9d2d329c41ce8d9d3982 346 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 245 261 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CU254_RS36035 5f45a92317da9d2d329c41ce8d9d3982 346 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 127 306 1.2E-54 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CU254_RS36035 5f45a92317da9d2d329c41ce8d9d3982 346 SUPERFAMILY SSF51735 121 306 3.59E-52 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS36035 5f45a92317da9d2d329c41ce8d9d3982 346 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 52 338 1.8E-19 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CU254_RS36035 5f45a92317da9d2d329c41ce8d9d3982 346 Gene3D G3DSA:3.40.50.720 134 309 3.5E-50 T 28-03-2018 CU254_RS36035 5f45a92317da9d2d329c41ce8d9d3982 346 Gene3D G3DSA:3.40.50.720 21 133 1.3E-26 T 28-03-2018 CU254_RS36035 5f45a92317da9d2d329c41ce8d9d3982 346 SUPERFAMILY SSF52283 47 154 1.89E-23 T 28-03-2018 CU254_RS19230 f0d5a3e23370ecd0e8b27be40fced8fe 411 Gene3D G3DSA:1.10.510.10 61 278 3.3E-18 T 28-03-2018 CU254_RS19230 f0d5a3e23370ecd0e8b27be40fced8fe 411 Pfam PF00069 Protein kinase domain 76 205 4.9E-8 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CU254_RS19230 f0d5a3e23370ecd0e8b27be40fced8fe 411 SUPERFAMILY SSF56112 11 243 3.18E-20 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS19230 f0d5a3e23370ecd0e8b27be40fced8fe 411 SMART SM00220 15 246 1.3E-4 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CU254_RS12390 80a894fd8721057ca0223258f612cafc 336 SUPERFAMILY SSF63380 105 198 1.13E-21 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CU254_RS12390 80a894fd8721057ca0223258f612cafc 336 Gene3D G3DSA:3.10.20.30 2 96 1.0E-20 T 28-03-2018 IPR012675 Beta-grasp domain CU254_RS12390 80a894fd8721057ca0223258f612cafc 336 Gene3D G3DSA:3.40.50.80 190 332 2.7E-19 T 28-03-2018 CU254_RS12390 80a894fd8721057ca0223258f612cafc 336 Pfam PF00175 Oxidoreductase NAD-binding domain 210 315 1.8E-9 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CU254_RS12390 80a894fd8721057ca0223258f612cafc 336 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 39 47 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CU254_RS12390 80a894fd8721057ca0223258f612cafc 336 Gene3D G3DSA:2.40.30.10 100 189 8.0E-19 T 28-03-2018 CU254_RS12390 80a894fd8721057ca0223258f612cafc 336 Pfam PF00970 Oxidoreductase FAD-binding domain 107 199 7.7E-15 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CU254_RS12390 80a894fd8721057ca0223258f612cafc 336 PRINTS PR00410 Phenol hydroxylase reductase family signature 132 144 9.6E-14 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CU254_RS12390 80a894fd8721057ca0223258f612cafc 336 PRINTS PR00410 Phenol hydroxylase reductase family signature 208 227 9.6E-14 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CU254_RS12390 80a894fd8721057ca0223258f612cafc 336 PRINTS PR00410 Phenol hydroxylase reductase family signature 302 310 9.6E-14 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CU254_RS12390 80a894fd8721057ca0223258f612cafc 336 PRINTS PR00410 Phenol hydroxylase reductase family signature 148 155 9.6E-14 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CU254_RS12390 80a894fd8721057ca0223258f612cafc 336 PRINTS PR00410 Phenol hydroxylase reductase family signature 192 201 9.6E-14 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CU254_RS12390 80a894fd8721057ca0223258f612cafc 336 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 10 83 2.3E-15 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CU254_RS12390 80a894fd8721057ca0223258f612cafc 336 SUPERFAMILY SSF54292 5 96 1.44E-25 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CU254_RS12390 80a894fd8721057ca0223258f612cafc 336 SUPERFAMILY SSF52343 202 335 6.42E-25 T 28-03-2018 CU254_RS08065 17bcdc42f5e160a1912dd9d5973a0f9d 406 Pfam PF01148 Cytidylyltransferase family 150 402 1.1E-52 T 28-03-2018 CU254_RS08065 17bcdc42f5e160a1912dd9d5973a0f9d 406 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 361 387 - T 28-03-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 CU254_RS20680 277f4195f40a1ac2fb46a140f444e6b5 567 SUPERFAMILY SSF75304 146 563 7.33E-103 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS20680 277f4195f40a1ac2fb46a140f444e6b5 567 Pfam PF01425 Amidase 148 552 3.3E-97 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS20680 277f4195f40a1ac2fb46a140f444e6b5 567 Gene3D G3DSA:3.90.1300.10 138 566 7.9E-109 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS13790 4d36962a19f54f2bb7a8763fa4a0a497 539 SUPERFAMILY SSF52540 15 236 4.77E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS13790 4d36962a19f54f2bb7a8763fa4a0a497 539 Gene3D G3DSA:3.40.50.300 1 306 7.7E-44 T 28-03-2018 CU254_RS13790 4d36962a19f54f2bb7a8763fa4a0a497 539 SUPERFAMILY SSF52540 347 523 1.45E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS13790 4d36962a19f54f2bb7a8763fa4a0a497 539 Pfam PF00005 ABC transporter 348 475 4.7E-12 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS13790 4d36962a19f54f2bb7a8763fa4a0a497 539 Pfam PF00005 ABC transporter 21 191 9.1E-21 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS13790 4d36962a19f54f2bb7a8763fa4a0a497 539 Gene3D G3DSA:3.40.50.300 323 538 9.5E-32 T 28-03-2018 CU254_RS13790 4d36962a19f54f2bb7a8763fa4a0a497 539 SMART SM00382 356 528 1.7E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS13790 4d36962a19f54f2bb7a8763fa4a0a497 539 SMART SM00382 29 236 2.4E-19 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS07710 91673c88b22594ed5045c3d91e425881 697 SUPERFAMILY SSF81665 47 115 1.07E-13 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CU254_RS07710 91673c88b22594ed5045c3d91e425881 697 SUPERFAMILY SSF81665 217 308 1.07E-13 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CU254_RS07710 91673c88b22594ed5045c3d91e425881 697 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 477 487 5.0E-25 T 28-03-2018 CU254_RS07710 91673c88b22594ed5045c3d91e425881 697 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 163 177 5.0E-25 T 28-03-2018 CU254_RS07710 91673c88b22594ed5045c3d91e425881 697 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 314 328 5.0E-25 T 28-03-2018 CU254_RS07710 91673c88b22594ed5045c3d91e425881 697 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 553 565 5.0E-25 T 28-03-2018 CU254_RS07710 91673c88b22594ed5045c3d91e425881 697 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 530 549 5.0E-25 T 28-03-2018 CU254_RS07710 91673c88b22594ed5045c3d91e425881 697 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 455 466 5.0E-25 T 28-03-2018 CU254_RS07710 91673c88b22594ed5045c3d91e425881 697 Gene3D G3DSA:3.40.1110.10 325 457 1.1E-20 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CU254_RS07710 91673c88b22594ed5045c3d91e425881 697 SUPERFAMILY SSF56784 405 579 2.47E-37 T 28-03-2018 IPR023214 HAD-like domain CU254_RS07710 91673c88b22594ed5045c3d91e425881 697 SUPERFAMILY SSF56784 313 332 2.47E-37 T 28-03-2018 IPR023214 HAD-like domain CU254_RS07710 91673c88b22594ed5045c3d91e425881 697 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 316 322 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CU254_RS07710 91673c88b22594ed5045c3d91e425881 697 TIGRFAM TIGR01497 kdpB: K+-transporting ATPase, B subunit 29 690 0.0 T 28-03-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 CU254_RS07710 91673c88b22594ed5045c3d91e425881 697 SUPERFAMILY SSF81653 120 216 2.62E-20 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CU254_RS07710 91673c88b22594ed5045c3d91e425881 697 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 27 694 39.975 T 28-03-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 CU254_RS07710 91673c88b22594ed5045c3d91e425881 697 Pfam PF00702 haloacid dehalogenase-like hydrolase 311 544 3.5E-32 T 28-03-2018 CU254_RS07710 91673c88b22594ed5045c3d91e425881 697 Pfam PF00122 E1-E2 ATPase 117 292 2.2E-34 T 28-03-2018 CU254_RS07710 91673c88b22594ed5045c3d91e425881 697 Gene3D G3DSA:3.40.50.1000 458 586 1.6E-33 T 28-03-2018 IPR023214 HAD-like domain CU254_RS07710 91673c88b22594ed5045c3d91e425881 697 Gene3D G3DSA:2.70.150.10 4 217 1.8E-25 T 28-03-2018 CU254_RS07710 91673c88b22594ed5045c3d91e425881 697 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 377 616 1.4E-42 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CU254_RS07710 91673c88b22594ed5045c3d91e425881 697 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 84 349 3.1E-33 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CU254_RS33425 b6c8ccf3a84644384feb2a5675a9986e 418 Pfam PF00135 Carboxylesterase family 12 242 9.2E-62 T 28-03-2018 IPR002018 Carboxylesterase, type B CU254_RS33425 b6c8ccf3a84644384feb2a5675a9986e 418 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 172 187 - T 28-03-2018 IPR019826 Carboxylesterase type B, active site CU254_RS33425 b6c8ccf3a84644384feb2a5675a9986e 418 SUPERFAMILY SSF53474 6 403 1.32E-78 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS33425 b6c8ccf3a84644384feb2a5675a9986e 418 Gene3D G3DSA:3.40.50.1820 2 309 8.2E-72 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS33425 b6c8ccf3a84644384feb2a5675a9986e 418 Gene3D G3DSA:3.40.50.1820 310 416 2.7E-10 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS24435 88f40716e49c295143f55540c0859b49 442 Gene3D G3DSA:3.90.1150.10 285 412 1.7E-28 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS24435 88f40716e49c295143f55540c0859b49 442 Gene3D G3DSA:3.40.640.10 44 284 7.2E-43 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS24435 88f40716e49c295143f55540c0859b49 442 SUPERFAMILY SSF53383 34 414 6.32E-80 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS24435 88f40716e49c295143f55540c0859b49 442 Pfam PF00266 Aminotransferase class-V 38 405 1.8E-75 T 28-03-2018 IPR000192 Aminotransferase class V domain CU254_RS24435 88f40716e49c295143f55540c0859b49 442 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 219 238 - T 28-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CU254_RS11720 0c42f605191283b27d031c58d711ba69 509 PIRSF PIRSF000110 9 509 8.0E-180 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CU254_RS11720 0c42f605191283b27d031c58d711ba69 509 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 26 209 1.9E-62 T 28-03-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CU254_RS11720 0c42f605191283b27d031c58d711ba69 509 SUPERFAMILY SSF51735 10 212 2.56E-62 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS11720 0c42f605191283b27d031c58d711ba69 509 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 22 508 87.557 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CU254_RS11720 0c42f605191283b27d031c58d711ba69 509 SUPERFAMILY SSF55347 199 507 3.6E-112 T 28-03-2018 CU254_RS11720 0c42f605191283b27d031c58d711ba69 509 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 241 258 3.5E-48 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CU254_RS11720 0c42f605191283b27d031c58d711ba69 509 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 189 217 3.5E-48 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CU254_RS11720 0c42f605191283b27d031c58d711ba69 509 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 259 275 3.5E-48 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CU254_RS11720 0c42f605191283b27d031c58d711ba69 509 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 348 374 3.5E-48 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CU254_RS11720 0c42f605191283b27d031c58d711ba69 509 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 165 178 3.5E-48 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CU254_RS11720 0c42f605191283b27d031c58d711ba69 509 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 211 507 7.8E-112 T 28-03-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CU254_RS11720 0c42f605191283b27d031c58d711ba69 509 Gene3D G3DSA:3.40.50.720 20 210 7.7E-69 T 28-03-2018 CU254_RS11720 0c42f605191283b27d031c58d711ba69 509 Gene3D G3DSA:3.30.360.10 211 509 2.5E-125 T 28-03-2018 CU254_RS11720 0c42f605191283b27d031c58d711ba69 509 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 23 508 1.7E-200 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CU254_RS11720 0c42f605191283b27d031c58d711ba69 509 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 199 205 - T 28-03-2018 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CU254_RS11035 fad0c131ab75bbee82cbe81f0357b525 484 SUPERFAMILY SSF48452 164 306 1.35E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS11035 fad0c131ab75bbee82cbe81f0357b525 484 Gene3D G3DSA:1.25.40.10 136 235 2.0E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS11035 fad0c131ab75bbee82cbe81f0357b525 484 Gene3D G3DSA:1.25.40.10 375 464 5.5E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS11035 fad0c131ab75bbee82cbe81f0357b525 484 Gene3D G3DSA:1.25.40.10 303 374 0.19 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS11035 fad0c131ab75bbee82cbe81f0357b525 484 SUPERFAMILY SSF48452 357 474 2.87E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS11035 fad0c131ab75bbee82cbe81f0357b525 484 Pfam PF13374 Tetratricopeptide repeat 436 472 6.5E-5 T 28-03-2018 CU254_RS11035 fad0c131ab75bbee82cbe81f0357b525 484 Gene3D G3DSA:1.10.10.10 236 302 2.6E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS11035 fad0c131ab75bbee82cbe81f0357b525 484 Pfam PF13424 Tetratricopeptide repeat 168 237 4.3E-10 T 28-03-2018 CU254_RS33105 a59157b034c568e4d1cc0d3466721f76 274 SUPERFAMILY SSF161098 4 270 2.22E-59 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS33105 a59157b034c568e4d1cc0d3466721f76 274 Gene3D G3DSA:1.10.3720.10 2 261 2.4E-37 T 28-03-2018 CU254_RS33105 a59157b034c568e4d1cc0d3466721f76 274 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 267 3.0E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS16500 4d9ba39f1f8d83f8156661742f0b95b9 324 Gene3D G3DSA:3.40.50.10860 1 135 5.1E-32 T 28-03-2018 CU254_RS16500 4d9ba39f1f8d83f8156661742f0b95b9 324 PIRSF PIRSF000188 1 324 1.3E-79 T 28-03-2018 IPR016211 Glutamate/phenylalanine/leucine/valine dehydrogenase, bacterial/archaeal GO:0016639|GO:0055114 CU254_RS16500 4d9ba39f1f8d83f8156661742f0b95b9 324 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 209 277 3.5E-7 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CU254_RS16500 4d9ba39f1f8d83f8156661742f0b95b9 324 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 162 189 - T 28-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 CU254_RS16500 4d9ba39f1f8d83f8156661742f0b95b9 324 SUPERFAMILY SSF51735 137 322 1.92E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS16500 4d9ba39f1f8d83f8156661742f0b95b9 324 SUPERFAMILY SSF53223 5 133 1.25E-29 T 28-03-2018 CU254_RS16500 4d9ba39f1f8d83f8156661742f0b95b9 324 Gene3D G3DSA:3.40.50.720 136 321 1.3E-32 T 28-03-2018 CU254_RS16500 4d9ba39f1f8d83f8156661742f0b95b9 324 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 122 144 1.6E-14 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CU254_RS16500 4d9ba39f1f8d83f8156661742f0b95b9 324 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 270 281 1.6E-14 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CU254_RS16500 4d9ba39f1f8d83f8156661742f0b95b9 324 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 52 66 1.6E-14 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CU254_RS16500 4d9ba39f1f8d83f8156661742f0b95b9 324 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 162 182 1.6E-14 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CU254_RS16500 4d9ba39f1f8d83f8156661742f0b95b9 324 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 15 116 1.5E-15 T 28-03-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CU254_RS16500 4d9ba39f1f8d83f8156661742f0b95b9 324 SMART SM00839 136 324 5.1E-22 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CU254_RS30790 6c2078240b51ddf1f92188550df2c397 314 SUPERFAMILY SSF53613 1 291 2.03E-67 T 28-03-2018 IPR029056 Ribokinase-like CU254_RS30790 6c2078240b51ddf1f92188550df2c397 314 Gene3D G3DSA:2.20.150.10 9 41 2.7E-16 T 28-03-2018 IPR023314 Tagatose-6-phosphate kinase/1-phosphofructokinase N-terminal domain CU254_RS30790 6c2078240b51ddf1f92188550df2c397 314 Pfam PF00294 pfkB family carbohydrate kinase 20 290 4.8E-46 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CU254_RS30790 6c2078240b51ddf1f92188550df2c397 314 TIGRFAM TIGR03828 pfkB: 1-phosphofructokinase 2 295 1.1E-99 T 28-03-2018 IPR022463 Fructose 1-phosphate kinase GO:0008662 KEGG: 00051+2.7.1.56 CU254_RS30790 6c2078240b51ddf1f92188550df2c397 314 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 295 2.4E-101 T 28-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 CU254_RS30790 6c2078240b51ddf1f92188550df2c397 314 Gene3D G3DSA:3.40.1190.20 42 295 6.4E-44 T 28-03-2018 IPR029056 Ribokinase-like CU254_RS30790 6c2078240b51ddf1f92188550df2c397 314 PIRSF PIRSF000535 1 299 2.0E-77 T 28-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 CU254_RS30790 6c2078240b51ddf1f92188550df2c397 314 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 246 259 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CU254_RS31930 6c52d7ad0044db684ea9f6b6f53b5dbf 149 Pfam PF01047 MarR family 39 87 1.6E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS31930 6c52d7ad0044db684ea9f6b6f53b5dbf 149 SMART SM00347 31 131 6.6E-17 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS31930 6c52d7ad0044db684ea9f6b6f53b5dbf 149 SUPERFAMILY SSF46785 9 146 6.95E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS31930 6c52d7ad0044db684ea9f6b6f53b5dbf 149 Gene3D G3DSA:1.10.10.10 2 148 5.0E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS36330 69d6d6e95726ad3cf649903a56e14f8e 801 SMART SM00382 206 345 3.1E-25 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS36330 69d6d6e95726ad3cf649903a56e14f8e 801 SUPERFAMILY SSF52540 166 413 3.85E-69 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS36330 69d6d6e95726ad3cf649903a56e14f8e 801 Gene3D G3DSA:3.40.50.300 147 352 1.5E-64 T 28-03-2018 CU254_RS36330 69d6d6e95726ad3cf649903a56e14f8e 801 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 210 341 4.2E-45 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CU254_RS36330 69d6d6e95726ad3cf649903a56e14f8e 801 Pfam PF01434 Peptidase family M41 405 612 6.7E-78 T 28-03-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 CU254_RS36330 69d6d6e95726ad3cf649903a56e14f8e 801 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 214 233 9.5E-5 T 28-03-2018 CU254_RS36330 69d6d6e95726ad3cf649903a56e14f8e 801 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 504 523 9.5E-5 T 28-03-2018 CU254_RS36330 69d6d6e95726ad3cf649903a56e14f8e 801 ProSitePatterns PS00674 AAA-protein family signature. 313 331 - T 28-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 CU254_RS36330 69d6d6e95726ad3cf649903a56e14f8e 801 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 123 613 1.0E-224 T 28-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 CU254_RS36330 69d6d6e95726ad3cf649903a56e14f8e 801 Gene3D G3DSA:1.10.8.60 353 436 2.5E-17 T 28-03-2018 CU254_RS36330 69d6d6e95726ad3cf649903a56e14f8e 801 SUPERFAMILY SSF140990 424 617 1.83E-67 T 28-03-2018 CU254_RS36330 69d6d6e95726ad3cf649903a56e14f8e 801 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 3 649 35.949 T 28-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 CU254_RS18425 dbb6f4e3c25578cdb063c0115a72c013 500 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 46 57 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CU254_RS18425 dbb6f4e3c25578cdb063c0115a72c013 500 Gene3D G3DSA:3.30.70.20 2 47 4.1E-13 T 28-03-2018 CU254_RS18425 dbb6f4e3c25578cdb063c0115a72c013 500 SUPERFAMILY SSF51971 369 414 2.41E-47 T 28-03-2018 CU254_RS18425 dbb6f4e3c25578cdb063c0115a72c013 500 SUPERFAMILY SSF51971 115 321 2.41E-47 T 28-03-2018 CU254_RS18425 dbb6f4e3c25578cdb063c0115a72c013 500 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 116 272 1.4E-10 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS18425 dbb6f4e3c25578cdb063c0115a72c013 500 Gene3D G3DSA:3.50.50.60 210 414 5.2E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS18425 dbb6f4e3c25578cdb063c0115a72c013 500 Gene3D G3DSA:3.30.70.20 48 92 4.9E-6 T 28-03-2018 CU254_RS18425 dbb6f4e3c25578cdb063c0115a72c013 500 PIRSF PIRSF000362 110 497 7.5E-104 T 28-03-2018 IPR021163 Ferredoxin-NADP+ reductase, adrenodoxin-type GO:0016491|GO:0055114 Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 CU254_RS18425 dbb6f4e3c25578cdb063c0115a72c013 500 SUPERFAMILY SSF54862 3 80 6.58E-18 T 28-03-2018 CU254_RS18425 dbb6f4e3c25578cdb063c0115a72c013 500 Pfam PF00037 4Fe-4S binding domain 40 61 2.4E-8 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CU254_RS18425 dbb6f4e3c25578cdb063c0115a72c013 500 PRINTS PR00419 Adrenodoxin reductase family signature 140 153 2.9E-16 T 28-03-2018 CU254_RS18425 dbb6f4e3c25578cdb063c0115a72c013 500 PRINTS PR00419 Adrenodoxin reductase family signature 183 193 2.9E-16 T 28-03-2018 CU254_RS18425 dbb6f4e3c25578cdb063c0115a72c013 500 PRINTS PR00419 Adrenodoxin reductase family signature 255 269 2.9E-16 T 28-03-2018 CU254_RS18425 dbb6f4e3c25578cdb063c0115a72c013 500 PRINTS PR00419 Adrenodoxin reductase family signature 116 138 2.9E-16 T 28-03-2018 CU254_RS18425 dbb6f4e3c25578cdb063c0115a72c013 500 Gene3D G3DSA:3.40.50.720 110 209 2.9E-13 T 28-03-2018 CU254_RS37385 65e3032ae84f8854f13677f970e5d2e2 381 Gene3D G3DSA:3.20.20.70 18 265 1.7E-54 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS37385 65e3032ae84f8854f13677f970e5d2e2 381 Pfam PF01207 Dihydrouridine synthase (Dus) 25 326 2.9E-101 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CU254_RS37385 65e3032ae84f8854f13677f970e5d2e2 381 Gene3D G3DSA:1.10.1200.80 269 340 1.5E-16 T 28-03-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 CU254_RS37385 65e3032ae84f8854f13677f970e5d2e2 381 SUPERFAMILY SSF51395 22 332 1.56E-80 T 28-03-2018 CU254_RS37385 65e3032ae84f8854f13677f970e5d2e2 381 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 15 335 2.6E-117 T 28-03-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 CU254_RS37385 65e3032ae84f8854f13677f970e5d2e2 381 PIRSF PIRSF006621 12 346 6.1E-108 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CU254_RS11025 e974535de9b0c386e987def8d606854b 702 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 516 598 2.1E-12 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CU254_RS11025 e974535de9b0c386e987def8d606854b 702 Pfam PF00378 Enoyl-CoA hydratase/isomerase 34 231 1.1E-25 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CU254_RS11025 e974535de9b0c386e987def8d606854b 702 SUPERFAMILY SSF48179 515 616 1.28E-15 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CU254_RS11025 e974535de9b0c386e987def8d606854b 702 SUPERFAMILY SSF48179 627 689 5.1E-11 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CU254_RS11025 e974535de9b0c386e987def8d606854b 702 SUPERFAMILY SSF52096 30 213 6.26E-42 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS11025 e974535de9b0c386e987def8d606854b 702 SUPERFAMILY SSF52096 246 321 6.26E-42 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS11025 e974535de9b0c386e987def8d606854b 702 Gene3D G3DSA:3.90.226.10 17 286 3.9E-42 T 28-03-2018 CU254_RS11025 e974535de9b0c386e987def8d606854b 702 Gene3D G3DSA:1.10.1040.10 625 696 2.0E-6 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CU254_RS11025 e974535de9b0c386e987def8d606854b 702 Gene3D G3DSA:1.10.1040.10 515 602 3.6E-14 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CU254_RS11025 e974535de9b0c386e987def8d606854b 702 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 333 512 1.4E-56 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CU254_RS11025 e974535de9b0c386e987def8d606854b 702 Gene3D G3DSA:3.40.50.720 287 514 5.4E-55 T 28-03-2018 CU254_RS11025 e974535de9b0c386e987def8d606854b 702 SUPERFAMILY SSF51735 330 512 1.52E-50 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS39510 3f6c4f050d37aef034d0565354df1ef0 458 SMART SM00331 11 235 4.6E-39 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CU254_RS39510 3f6c4f050d37aef034d0565354df1ef0 458 SMART SM00332 2 233 1.3E-32 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CU254_RS39510 3f6c4f050d37aef034d0565354df1ef0 458 SUPERFAMILY SSF81606 4 234 5.49E-65 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CU254_RS39510 3f6c4f050d37aef034d0565354df1ef0 458 Gene3D G3DSA:3.60.40.10 5 235 1.4E-40 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CU254_RS39510 3f6c4f050d37aef034d0565354df1ef0 458 Pfam PF13672 Protein phosphatase 2C 18 199 2.7E-13 T 28-03-2018 CU254_RS20905 ee23a9de89aeccf3499a917a7bfe6bb3 169 SMART SM00347 45 148 1.1E-14 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS20905 ee23a9de89aeccf3499a917a7bfe6bb3 169 Gene3D G3DSA:1.10.10.10 2 164 6.7E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS20905 ee23a9de89aeccf3499a917a7bfe6bb3 169 PRINTS PR00598 Bacterial regulatory protein MarR family signature 72 88 7.7E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS20905 ee23a9de89aeccf3499a917a7bfe6bb3 169 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 104 7.7E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS20905 ee23a9de89aeccf3499a917a7bfe6bb3 169 PRINTS PR00598 Bacterial regulatory protein MarR family signature 108 124 7.7E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS20905 ee23a9de89aeccf3499a917a7bfe6bb3 169 SUPERFAMILY SSF46785 22 159 2.93E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS20905 ee23a9de89aeccf3499a917a7bfe6bb3 169 Pfam PF12802 MarR family 54 112 1.3E-10 T 28-03-2018 CU254_RS25735 27690359bba228820d263961bdf6de6c 326 SUPERFAMILY SSF51735 9 154 9.67E-30 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS25735 27690359bba228820d263961bdf6de6c 326 Gene3D G3DSA:3.40.50.720 5 158 3.3E-24 T 28-03-2018 CU254_RS25735 27690359bba228820d263961bdf6de6c 326 Gene3D G3DSA:1.10.1040.10 160 291 6.5E-13 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CU254_RS25735 27690359bba228820d263961bdf6de6c 326 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 9 154 4.8E-21 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CU254_RS25735 27690359bba228820d263961bdf6de6c 326 PIRSF PIRSF000103 4 294 6.2E-37 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CU254_RS16955 c0f3d973f6338775d8710dc2f9e150e8 477 Pfam PF01494 FAD binding domain 2 333 2.6E-87 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CU254_RS16955 c0f3d973f6338775d8710dc2f9e150e8 477 Gene3D G3DSA:3.50.50.60 1 383 1.2E-66 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS16955 c0f3d973f6338775d8710dc2f9e150e8 477 SUPERFAMILY SSF51905 2 168 7.93E-65 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS16955 c0f3d973f6338775d8710dc2f9e150e8 477 SUPERFAMILY SSF51905 254 343 7.93E-65 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS16955 c0f3d973f6338775d8710dc2f9e150e8 477 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 267 282 1.2E-44 T 28-03-2018 CU254_RS16955 c0f3d973f6338775d8710dc2f9e150e8 477 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 147 162 1.2E-44 T 28-03-2018 CU254_RS16955 c0f3d973f6338775d8710dc2f9e150e8 477 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 282 298 1.2E-44 T 28-03-2018 CU254_RS16955 c0f3d973f6338775d8710dc2f9e150e8 477 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 1.2E-44 T 28-03-2018 CU254_RS16955 c0f3d973f6338775d8710dc2f9e150e8 477 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 300 318 1.2E-44 T 28-03-2018 CU254_RS16955 c0f3d973f6338775d8710dc2f9e150e8 477 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 318 334 1.2E-44 T 28-03-2018 CU254_RS38900 f21615bccad647da807690703a399ea8 352 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 140 237 4.3E-10 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CU254_RS38900 f21615bccad647da807690703a399ea8 352 SUPERFAMILY SSF51735 5 161 3.95E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS38900 f21615bccad647da807690703a399ea8 352 SUPERFAMILY SSF55347 133 290 1.23E-28 T 28-03-2018 CU254_RS38900 f21615bccad647da807690703a399ea8 352 Gene3D G3DSA:3.40.50.720 1 137 1.1E-32 T 28-03-2018 CU254_RS38900 f21615bccad647da807690703a399ea8 352 Gene3D G3DSA:3.30.360.10 138 351 9.7E-47 T 28-03-2018 CU254_RS38900 f21615bccad647da807690703a399ea8 352 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 6 124 4.5E-22 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CU254_RS33190 0ac73d61ec784d713ee6c1669d4a3f8c 284 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 100 272 2.4E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS33190 0ac73d61ec784d713ee6c1669d4a3f8c 284 Gene3D G3DSA:1.10.3720.10 8 271 1.0E-34 T 28-03-2018 CU254_RS33190 0ac73d61ec784d713ee6c1669d4a3f8c 284 SUPERFAMILY SSF161098 18 284 1.23E-62 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS10610 fb2eb35c1c8ea9b77524245dac0abd23 261 Gene3D G3DSA:2.40.10.10 35 45 1.6E-4 T 28-03-2018 CU254_RS10610 fb2eb35c1c8ea9b77524245dac0abd23 261 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 204 215 - T 28-03-2018 IPR033116 Serine proteases, trypsin family, serine active site CU254_RS10610 fb2eb35c1c8ea9b77524245dac0abd23 261 Gene3D G3DSA:2.40.10.10 68 260 4.6E-52 T 28-03-2018 CU254_RS10610 fb2eb35c1c8ea9b77524245dac0abd23 261 SMART SM00020 35 254 5.0E-63 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CU254_RS10610 fb2eb35c1c8ea9b77524245dac0abd23 261 SUPERFAMILY SSF50494 26 254 1.87E-57 T 28-03-2018 IPR009003 Peptidase S1, PA clan CU254_RS10610 fb2eb35c1c8ea9b77524245dac0abd23 261 Pfam PF00089 Trypsin 36 254 1.3E-49 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CU254_RS10610 fb2eb35c1c8ea9b77524245dac0abd23 261 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 113 127 1.0E-12 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CU254_RS10610 fb2eb35c1c8ea9b77524245dac0abd23 261 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 58 73 1.0E-12 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CU254_RS10610 fb2eb35c1c8ea9b77524245dac0abd23 261 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 203 215 1.0E-12 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CU254_RS10610 fb2eb35c1c8ea9b77524245dac0abd23 261 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 68 73 - T 28-03-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 CU254_RS10610 fb2eb35c1c8ea9b77524245dac0abd23 261 Gene3D G3DSA:2.40.10.10 46 67 2.0E-13 T 28-03-2018 CU254_RS04165 a69567b0e006d2c9afb0c67e28cf1e4e 430 Gene3D G3DSA:3.30.830.10 232 430 3.5E-23 T 28-03-2018 CU254_RS04165 a69567b0e006d2c9afb0c67e28cf1e4e 430 Gene3D G3DSA:3.30.830.10 2 227 2.6E-52 T 28-03-2018 CU254_RS04165 a69567b0e006d2c9afb0c67e28cf1e4e 430 Pfam PF00675 Insulinase (Peptidase family M16) 16 132 2.1E-19 T 28-03-2018 IPR011765 Peptidase M16, N-terminal CU254_RS04165 a69567b0e006d2c9afb0c67e28cf1e4e 430 SUPERFAMILY SSF63411 3 220 3.47E-49 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CU254_RS04165 a69567b0e006d2c9afb0c67e28cf1e4e 430 SUPERFAMILY SSF63411 240 425 2.5E-22 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CU254_RS04165 a69567b0e006d2c9afb0c67e28cf1e4e 430 Pfam PF05193 Peptidase M16 inactive domain 173 352 1.2E-25 T 28-03-2018 IPR007863 Peptidase M16, C-terminal CU254_RS19545 8fd70477e31b6e3b69a61acc3d6dcf12 1032 Gene3D G3DSA:1.20.1050.60 490 584 1.5E-29 T 28-03-2018 CU254_RS19545 8fd70477e31b6e3b69a61acc3d6dcf12 1032 Gene3D G3DSA:2.60.120.260 8 162 3.3E-4 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS19545 8fd70477e31b6e3b69a61acc3d6dcf12 1032 Gene3D G3DSA:3.30.2080.10 734 904 7.8E-51 T 28-03-2018 CU254_RS19545 8fd70477e31b6e3b69a61acc3d6dcf12 1032 Pfam PF07971 Glycosyl hydrolase family 92 377 891 1.8E-143 T 28-03-2018 IPR012939 Glycosyl hydrolase family 92 CU254_RS19545 8fd70477e31b6e3b69a61acc3d6dcf12 1032 TIGRFAM TIGR01180 aman2_put: putative alpha-1,2-mannosidase 159 895 1.6E-136 T 28-03-2018 IPR005887 Alpha-1,2-mannosidase, putative CU254_RS19545 8fd70477e31b6e3b69a61acc3d6dcf12 1032 SUPERFAMILY SSF48208 404 819 6.89E-14 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CU254_RS19545 8fd70477e31b6e3b69a61acc3d6dcf12 1032 Gene3D G3DSA:2.60.40.1180 915 1032 1.8E-8 T 28-03-2018 CU254_RS19545 8fd70477e31b6e3b69a61acc3d6dcf12 1032 Gene3D G3DSA:2.70.98.10 163 454 1.5E-71 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 CU254_RS38525 f11e09cff24a55e55a2a58902851e907 319 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 66 179 5.4E-17 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CU254_RS38525 f11e09cff24a55e55a2a58902851e907 319 Gene3D G3DSA:1.10.3720.10 30 290 1.7E-45 T 28-03-2018 CU254_RS38525 f11e09cff24a55e55a2a58902851e907 319 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 282 3.3E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS38525 f11e09cff24a55e55a2a58902851e907 319 SUPERFAMILY SSF161098 64 270 2.09E-44 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS03635 196ae2742833300b20212efd4f020de6 357 Gene3D G3DSA:3.40.630.10 5 175 5.9E-18 T 28-03-2018 CU254_RS03635 196ae2742833300b20212efd4f020de6 357 Pfam PF07687 Peptidase dimerisation domain 172 268 5.8E-12 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CU254_RS03635 196ae2742833300b20212efd4f020de6 357 SUPERFAMILY SSF53187 278 356 5.24E-36 T 28-03-2018 CU254_RS03635 196ae2742833300b20212efd4f020de6 357 SUPERFAMILY SSF53187 11 184 5.24E-36 T 28-03-2018 CU254_RS03635 196ae2742833300b20212efd4f020de6 357 Gene3D G3DSA:3.30.70.360 176 280 1.0E-20 T 28-03-2018 CU254_RS03635 196ae2742833300b20212efd4f020de6 357 Pfam PF01546 Peptidase family M20/M25/M40 67 356 2.2E-19 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CU254_RS03635 196ae2742833300b20212efd4f020de6 357 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 99 134 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CU254_RS03635 196ae2742833300b20212efd4f020de6 357 SUPERFAMILY SSF55031 172 273 1.38E-17 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CU254_RS03635 196ae2742833300b20212efd4f020de6 357 TIGRFAM TIGR01900 dapE-gram_pos: succinyl-diaminopimelate desuccinylase 7 356 6.9E-152 T 28-03-2018 IPR010174 Succinyl-diaminopimelate desuccinylase, DapE GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 CU254_RS37405 552d3088ec6e8b62dd2f05f14d5985b5 214 SUPERFAMILY SSF55073 56 203 4.47E-39 T 28-03-2018 IPR029787 Nucleotide cyclase CU254_RS37405 552d3088ec6e8b62dd2f05f14d5985b5 214 Pfam PF00990 Diguanylate cyclase, GGDEF domain 52 198 7.2E-33 T 28-03-2018 IPR000160 GGDEF domain CU254_RS37405 552d3088ec6e8b62dd2f05f14d5985b5 214 Gene3D G3DSA:3.30.70.270 49 213 7.5E-46 T 28-03-2018 CU254_RS37405 552d3088ec6e8b62dd2f05f14d5985b5 214 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 51 201 3.4E-35 T 28-03-2018 IPR000160 GGDEF domain CU254_RS37405 552d3088ec6e8b62dd2f05f14d5985b5 214 SMART SM00267 41 202 7.9E-45 T 28-03-2018 IPR000160 GGDEF domain CU254_RS25745 9dc4d49d136384e29d4ec779f284d6c4 286 Gene3D G3DSA:3.40.50.720 1 154 5.4E-25 T 28-03-2018 CU254_RS25745 9dc4d49d136384e29d4ec779f284d6c4 286 Gene3D G3DSA:1.10.1040.10 157 286 9.1E-11 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CU254_RS25745 9dc4d49d136384e29d4ec779f284d6c4 286 SUPERFAMILY SSF51735 1 151 7.17E-29 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS25745 9dc4d49d136384e29d4ec779f284d6c4 286 PIRSF PIRSF000103 1 286 1.2E-35 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CU254_RS25745 9dc4d49d136384e29d4ec779f284d6c4 286 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 151 1.3E-21 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CU254_RS06855 c3dfa1ca0b529676e9f4f2709d5307a4 168 Pfam PF01842 ACT domain 4 69 1.4E-17 T 28-03-2018 IPR002912 ACT domain CU254_RS06855 c3dfa1ca0b529676e9f4f2709d5307a4 168 Gene3D G3DSA:3.30.70.260 1 88 2.7E-25 T 28-03-2018 CU254_RS06855 c3dfa1ca0b529676e9f4f2709d5307a4 168 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 4 74 2.0E-31 T 28-03-2018 CU254_RS06855 c3dfa1ca0b529676e9f4f2709d5307a4 168 Gene3D G3DSA:3.30.70.1150 89 161 6.5E-29 T 28-03-2018 CU254_RS06855 c3dfa1ca0b529676e9f4f2709d5307a4 168 SUPERFAMILY SSF55021 81 161 3.32E-25 T 28-03-2018 CU254_RS06855 c3dfa1ca0b529676e9f4f2709d5307a4 168 Pfam PF10369 Small subunit of acetolactate synthase 85 158 3.0E-27 T 28-03-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CU254_RS06855 c3dfa1ca0b529676e9f4f2709d5307a4 168 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 4 158 1.1E-62 T 28-03-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CU254_RS06855 c3dfa1ca0b529676e9f4f2709d5307a4 168 SUPERFAMILY SSF55021 4 76 9.6E-24 T 28-03-2018 CU254_RS21015 997ea683de4b7d26d50633f4a46415e5 271 Pfam PF01738 Dienelactone hydrolase family 194 261 2.6E-6 T 28-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 CU254_RS21015 997ea683de4b7d26d50633f4a46415e5 271 SUPERFAMILY SSF53474 7 270 1.08E-39 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS21015 997ea683de4b7d26d50633f4a46415e5 271 Pfam PF12146 Serine aminopeptidase, S33 28 142 1.3E-9 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 CU254_RS21015 997ea683de4b7d26d50633f4a46415e5 271 Gene3D G3DSA:3.40.50.1820 3 271 1.7E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS15725 bb1954be4bd14d4512882e1d85f1929f 797 Gene3D G3DSA:3.30.365.10 286 449 3.7E-37 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CU254_RS15725 bb1954be4bd14d4512882e1d85f1929f 797 Gene3D G3DSA:3.30.365.10 455 626 1.4E-34 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CU254_RS15725 bb1954be4bd14d4512882e1d85f1929f 797 Gene3D G3DSA:3.90.1170.50 11 146 2.0E-33 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CU254_RS15725 bb1954be4bd14d4512882e1d85f1929f 797 Gene3D G3DSA:3.30.365.10 627 796 1.1E-40 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CU254_RS15725 bb1954be4bd14d4512882e1d85f1929f 797 Gene3D G3DSA:3.30.365.10 181 285 6.2E-29 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CU254_RS15725 bb1954be4bd14d4512882e1d85f1929f 797 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 162 723 5.1E-150 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CU254_RS15725 bb1954be4bd14d4512882e1d85f1929f 797 SUPERFAMILY SSF54665 16 169 1.28E-43 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CU254_RS15725 bb1954be4bd14d4512882e1d85f1929f 797 SUPERFAMILY SSF56003 139 787 3.93E-173 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CU254_RS15725 bb1954be4bd14d4512882e1d85f1929f 797 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 32 145 6.0E-23 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CU254_RS15725 bb1954be4bd14d4512882e1d85f1929f 797 SMART SM01008 32 146 1.8E-42 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CU254_RS19930 1969f18a401f058b29b893e92bedfc09 221 Gene3D G3DSA:1.20.1300.10 2 221 3.7E-52 T 28-03-2018 CU254_RS19930 1969f18a401f058b29b893e92bedfc09 221 TIGRFAM TIGR02046 sdhC_b558_fam: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family 6 219 2.8E-65 T 28-03-2018 IPR011138 Succinate dehydrogenase cytochrome b558 subunit CU254_RS19930 1969f18a401f058b29b893e92bedfc09 221 SUPERFAMILY SSF81343 2 219 1.26E-50 T 28-03-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CU254_RS03415 3d5c256f34a0b289d620423bf53c17ea 394 SUPERFAMILY SSF52440 7 102 5.18E-21 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CU254_RS03415 3d5c256f34a0b289d620423bf53c17ea 394 SUPERFAMILY SSF56059 106 306 1.59E-56 T 28-03-2018 CU254_RS03415 3d5c256f34a0b289d620423bf53c17ea 394 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 10 372 7.6E-114 T 28-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 CU254_RS03415 3d5c256f34a0b289d620423bf53c17ea 394 Gene3D G3DSA:3.30.1490.20 106 191 2.3E-17 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CU254_RS03415 3d5c256f34a0b289d620423bf53c17ea 394 Gene3D G3DSA:3.30.470.20 192 383 1.7E-41 T 28-03-2018 CU254_RS03415 3d5c256f34a0b289d620423bf53c17ea 394 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 9 368 38.343 T 28-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 CU254_RS03415 3d5c256f34a0b289d620423bf53c17ea 394 Gene3D G3DSA:3.40.50.20 7 93 1.9E-19 T 28-03-2018 CU254_RS03415 3d5c256f34a0b289d620423bf53c17ea 394 SUPERFAMILY SSF51246 312 389 5.81E-17 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CU254_RS03415 3d5c256f34a0b289d620423bf53c17ea 394 Pfam PF02222 ATP-grasp domain 117 285 8.5E-48 T 28-03-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type CU254_RS03415 3d5c256f34a0b289d620423bf53c17ea 394 SMART SM01209 105 268 0.0017 T 28-03-2018 CU254_RS27430 4963d206c5bef27a71972326bfcc8bdf 220 SUPERFAMILY SSF50475 34 140 1.07E-12 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS27430 4963d206c5bef27a71972326bfcc8bdf 220 TIGRFAM TIGR04025 PPOX_FMN_DR2398: pyridoxamine 5'-phosphate oxidase, FMN-binding family 16 172 7.8E-54 T 28-03-2018 IPR024029 Pyridoxamine 5-phosphate oxidase, FMN-dependent CU254_RS27430 4963d206c5bef27a71972326bfcc8bdf 220 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 41 128 1.4E-11 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CU254_RS27430 4963d206c5bef27a71972326bfcc8bdf 220 Gene3D G3DSA:2.30.110.10 26 179 3.3E-21 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS19850 2902c165089fc7c4695d20130cc2ad3b 110 Pfam PF01022 Bacterial regulatory protein, arsR family 20 64 8.0E-16 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS19850 2902c165089fc7c4695d20130cc2ad3b 110 SUPERFAMILY SSF46785 8 91 2.25E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS19850 2902c165089fc7c4695d20130cc2ad3b 110 Gene3D G3DSA:1.10.10.10 2 99 2.9E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS19850 2902c165089fc7c4695d20130cc2ad3b 110 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 47 62 1.7E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS19850 2902c165089fc7c4695d20130cc2ad3b 110 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 62 77 1.7E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS19850 2902c165089fc7c4695d20130cc2ad3b 110 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 15 30 1.7E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS19850 2902c165089fc7c4695d20130cc2ad3b 110 SMART SM00418 13 91 2.9E-27 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS26850 bc59e27edb2b8b9fcbf5cb4bcf00e2c4 476 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 159 170 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CU254_RS26850 bc59e27edb2b8b9fcbf5cb4bcf00e2c4 476 PRINTS PR00723 Subtilisin serine protease family (S8) signature 154 173 2.2E-19 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CU254_RS26850 bc59e27edb2b8b9fcbf5cb4bcf00e2c4 476 PRINTS PR00723 Subtilisin serine protease family (S8) signature 386 402 2.2E-19 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CU254_RS26850 bc59e27edb2b8b9fcbf5cb4bcf00e2c4 476 PRINTS PR00723 Subtilisin serine protease family (S8) signature 200 213 2.2E-19 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CU254_RS26850 bc59e27edb2b8b9fcbf5cb4bcf00e2c4 476 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 387 397 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CU254_RS26850 bc59e27edb2b8b9fcbf5cb4bcf00e2c4 476 Pfam PF00082 Subtilase family 155 437 1.3E-44 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS26850 bc59e27edb2b8b9fcbf5cb4bcf00e2c4 476 Gene3D G3DSA:3.40.50.200 95 471 5.4E-72 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS26850 bc59e27edb2b8b9fcbf5cb4bcf00e2c4 476 SUPERFAMILY SSF52743 135 468 2.88E-68 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS26850 bc59e27edb2b8b9fcbf5cb4bcf00e2c4 476 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 204 214 - T 28-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site CU254_RS29090 b31a62b2ce8574ceea2d9ccef4740014 314 Gene3D G3DSA:1.10.10.10 2 103 2.4E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS29090 b31a62b2ce8574ceea2d9ccef4740014 314 Pfam PF03466 LysR substrate binding domain 101 297 8.9E-33 T 28-03-2018 IPR005119 LysR, substrate-binding CU254_RS29090 b31a62b2ce8574ceea2d9ccef4740014 314 Gene3D G3DSA:3.40.190.10 104 189 1.6E-16 T 28-03-2018 CU254_RS29090 b31a62b2ce8574ceea2d9ccef4740014 314 SUPERFAMILY SSF53850 101 300 2.79E-29 T 28-03-2018 CU254_RS29090 b31a62b2ce8574ceea2d9ccef4740014 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 40 7.4E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS29090 b31a62b2ce8574ceea2d9ccef4740014 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 50 7.4E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS29090 b31a62b2ce8574ceea2d9ccef4740014 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 50 61 7.4E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS29090 b31a62b2ce8574ceea2d9ccef4740014 314 SUPERFAMILY SSF46785 7 124 5.67E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS29090 b31a62b2ce8574ceea2d9ccef4740014 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 16 74 1.0E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS29090 b31a62b2ce8574ceea2d9ccef4740014 314 Gene3D G3DSA:3.40.190.10 190 271 2.8E-12 T 28-03-2018 CU254_RS22235 c7fa505d7e097dc54ee25f5728bf8613 451 SUPERFAMILY SSF63737 14 205 1.7E-35 T 28-03-2018 CU254_RS22235 c7fa505d7e097dc54ee25f5728bf8613 451 Pfam PF01433 Peptidase family M1 domain 249 442 5.3E-27 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CU254_RS22235 c7fa505d7e097dc54ee25f5728bf8613 451 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 142 157 8.2E-16 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CU254_RS22235 c7fa505d7e097dc54ee25f5728bf8613 451 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 189 204 8.2E-16 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CU254_RS22235 c7fa505d7e097dc54ee25f5728bf8613 451 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 304 319 8.2E-16 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CU254_RS22235 c7fa505d7e097dc54ee25f5728bf8613 451 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 323 335 8.2E-16 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CU254_RS22235 c7fa505d7e097dc54ee25f5728bf8613 451 SUPERFAMILY SSF55486 226 450 1.74E-54 T 28-03-2018 CU254_RS22235 c7fa505d7e097dc54ee25f5728bf8613 451 Gene3D G3DSA:1.10.390.10 292 446 2.9E-35 T 28-03-2018 CU254_RS22235 c7fa505d7e097dc54ee25f5728bf8613 451 Gene3D G3DSA:2.60.40.1730 23 207 2.0E-38 T 28-03-2018 CU254_RS22030 bbe24679873c51117228cccbbdbe3303 771 Gene3D G3DSA:3.40.50.970 13 387 9.0E-49 T 28-03-2018 CU254_RS22030 bbe24679873c51117228cccbbdbe3303 771 SUPERFAMILY SSF52518 6 359 5.44E-64 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS22030 bbe24679873c51117228cccbbdbe3303 771 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 74 229 4.2E-9 T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CU254_RS22030 bbe24679873c51117228cccbbdbe3303 771 Gene3D G3DSA:3.40.50.970 389 618 5.1E-35 T 28-03-2018 CU254_RS22030 bbe24679873c51117228cccbbdbe3303 771 SUPERFAMILY SSF52518 393 609 7.77E-47 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS22030 bbe24679873c51117228cccbbdbe3303 771 SMART SM00861 405 609 1.9E-5 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CU254_RS22030 bbe24679873c51117228cccbbdbe3303 771 Gene3D G3DSA:3.40.50.920 630 769 9.0E-25 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CU254_RS22030 bbe24679873c51117228cccbbdbe3303 771 PIRSF PIRSF000156 1 770 6.5E-68 T 28-03-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 CU254_RS22030 bbe24679873c51117228cccbbdbe3303 771 SUPERFAMILY SSF52922 624 769 3.93E-24 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CU254_RS29860 aff7ce53a5b7287216b97a5bf7ff08bc 997 Gene3D G3DSA:1.25.40.10 768 815 2.0E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS29860 aff7ce53a5b7287216b97a5bf7ff08bc 997 Gene3D G3DSA:1.25.40.10 103 265 3.3E-16 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS29860 aff7ce53a5b7287216b97a5bf7ff08bc 997 SMART SM00028 797 830 5.1 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS29860 aff7ce53a5b7287216b97a5bf7ff08bc 997 SMART SM00028 717 750 0.43 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS29860 aff7ce53a5b7287216b97a5bf7ff08bc 997 SMART SM00028 757 790 7.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS29860 aff7ce53a5b7287216b97a5bf7ff08bc 997 SMART SM00028 196 229 320.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS29860 aff7ce53a5b7287216b97a5bf7ff08bc 997 SMART SM00028 106 139 440.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS29860 aff7ce53a5b7287216b97a5bf7ff08bc 997 SMART SM00028 915 948 30.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS29860 aff7ce53a5b7287216b97a5bf7ff08bc 997 SUPERFAMILY SSF48452 97 269 1.12E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS29860 aff7ce53a5b7287216b97a5bf7ff08bc 997 Gene3D G3DSA:1.25.40.10 886 969 1.1E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS29860 aff7ce53a5b7287216b97a5bf7ff08bc 997 Pfam PF00931 NB-ARC domain 285 525 5.0E-12 T 28-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 CU254_RS29860 aff7ce53a5b7287216b97a5bf7ff08bc 997 Pfam PF00486 Transcriptional regulatory protein, C terminal 27 79 4.7E-5 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS29860 aff7ce53a5b7287216b97a5bf7ff08bc 997 Gene3D G3DSA:1.10.150.200 697 767 7.2E-8 T 28-03-2018 CU254_RS29860 aff7ce53a5b7287216b97a5bf7ff08bc 997 SUPERFAMILY SSF48452 711 861 2.11E-18 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS29860 aff7ce53a5b7287216b97a5bf7ff08bc 997 Gene3D G3DSA:1.25.40.10 816 885 0.0017 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS29860 aff7ce53a5b7287216b97a5bf7ff08bc 997 Pfam PF13181 Tetratricopeptide repeat 719 749 0.036 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS29860 aff7ce53a5b7287216b97a5bf7ff08bc 997 Gene3D G3DSA:3.40.50.300 266 422 1.3E-20 T 28-03-2018 CU254_RS29860 aff7ce53a5b7287216b97a5bf7ff08bc 997 Pfam PF03704 Bacterial transcriptional activator domain 101 246 8.0E-15 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CU254_RS29860 aff7ce53a5b7287216b97a5bf7ff08bc 997 Gene3D G3DSA:1.10.10.10 8 102 2.4E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS29860 aff7ce53a5b7287216b97a5bf7ff08bc 997 SUPERFAMILY SSF46894 21 92 3.12E-8 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS29860 aff7ce53a5b7287216b97a5bf7ff08bc 997 SUPERFAMILY SSF52540 269 533 1.68E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS29860 aff7ce53a5b7287216b97a5bf7ff08bc 997 PRINTS PR00364 Disease resistance protein signature 379 393 2.0E-9 T 28-03-2018 CU254_RS29860 aff7ce53a5b7287216b97a5bf7ff08bc 997 PRINTS PR00364 Disease resistance protein signature 466 480 2.0E-9 T 28-03-2018 CU254_RS29860 aff7ce53a5b7287216b97a5bf7ff08bc 997 PRINTS PR00364 Disease resistance protein signature 302 317 2.0E-9 T 28-03-2018 CU254_RS29860 aff7ce53a5b7287216b97a5bf7ff08bc 997 SMART SM01043 101 246 7.6E-10 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CU254_RS29860 aff7ce53a5b7287216b97a5bf7ff08bc 997 SMART SM00382 299 441 4.5E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS21465 e2dc7201975bee674395a4c5bcebf258 552 Gene3D G3DSA:1.20.1640.10 296 512 4.5E-25 T 28-03-2018 CU254_RS21465 e2dc7201975bee674395a4c5bcebf258 552 SUPERFAMILY SSF82866 313 510 7.06E-33 T 28-03-2018 CU254_RS21465 e2dc7201975bee674395a4c5bcebf258 552 Pfam PF07549 SecD/SecF GG Motif 21 39 3.1E-4 T 28-03-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site CU254_RS21465 e2dc7201975bee674395a4c5bcebf258 552 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 266 498 4.8E-67 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CU254_RS21465 e2dc7201975bee674395a4c5bcebf258 552 Pfam PF02355 Protein export membrane protein 338 511 5.1E-9 T 28-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial CU254_RS21465 e2dc7201975bee674395a4c5bcebf258 552 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 1 522 37.926 T 28-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 CU254_RS21465 e2dc7201975bee674395a4c5bcebf258 552 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 22 507 4.9E-122 T 28-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 CU254_RS29440 23b5f6ae738fe09144943c68efa36dd0 369 TIGRFAM TIGR01928 menC_lowGC/arch: o-succinylbenzoate synthase 11 331 4.4E-81 T 28-03-2018 IPR010197 o-Succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00010+4.2.1.11|KEGG: 00130+4.2.1.113|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-5837|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CU254_RS29440 23b5f6ae738fe09144943c68efa36dd0 369 SUPERFAMILY SSF54826 1 125 2.19E-23 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CU254_RS29440 23b5f6ae738fe09144943c68efa36dd0 369 Pfam PF13378 Enolase C-terminal domain-like 147 353 5.0E-45 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CU254_RS29440 23b5f6ae738fe09144943c68efa36dd0 369 SUPERFAMILY SSF51604 113 363 3.67E-64 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CU254_RS29440 23b5f6ae738fe09144943c68efa36dd0 369 Gene3D G3DSA:3.20.20.120 134 348 2.3E-56 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CU254_RS29440 23b5f6ae738fe09144943c68efa36dd0 369 Hamap MF_01933 o-succinylbenzoate synthase [menC]. 1 359 38.771 T 28-03-2018 IPR010197 o-Succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00010+4.2.1.11|KEGG: 00130+4.2.1.113|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-5837|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CU254_RS29440 23b5f6ae738fe09144943c68efa36dd0 369 Gene3D G3DSA:3.30.390.10 1 133 3.9E-21 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CU254_RS29440 23b5f6ae738fe09144943c68efa36dd0 369 SMART SM00922 143 235 1.0E-17 T 28-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CU254_RS17600 b2914a98e65130ce3bb9f283ed6da536 487 Pfam PF00155 Aminotransferase class I and II 181 471 8.4E-15 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CU254_RS17600 b2914a98e65130ce3bb9f283ed6da536 487 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 53 69 2.2E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS17600 b2914a98e65130ce3bb9f283ed6da536 487 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 39 53 2.2E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS17600 b2914a98e65130ce3bb9f283ed6da536 487 SMART SM00345 20 79 6.5E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS17600 b2914a98e65130ce3bb9f283ed6da536 487 Gene3D G3DSA:3.40.640.10 168 379 3.3E-34 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS17600 b2914a98e65130ce3bb9f283ed6da536 487 Gene3D G3DSA:3.90.1150.10 380 485 9.4E-17 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS17600 b2914a98e65130ce3bb9f283ed6da536 487 SUPERFAMILY SSF53383 104 484 5.23E-79 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS17600 b2914a98e65130ce3bb9f283ed6da536 487 Gene3D G3DSA:1.10.10.10 3 81 5.3E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS17600 b2914a98e65130ce3bb9f283ed6da536 487 SUPERFAMILY SSF46785 9 81 2.35E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS17600 b2914a98e65130ce3bb9f283ed6da536 487 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 79 8.3E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS06890 3484586eb8b24d16d051dd0cd3d4655e 342 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS06890 3484586eb8b24d16d051dd0cd3d4655e 342 Gene3D G3DSA:1.25.10.10 250 333 1.5E-4 T 28-03-2018 IPR011989 Armadillo-like helical CU254_RS06890 3484586eb8b24d16d051dd0cd3d4655e 342 Pfam PF13411 MerR HTH family regulatory protein 3 68 2.9E-15 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS06890 3484586eb8b24d16d051dd0cd3d4655e 342 SMART SM00422 1 70 2.1E-20 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS06890 3484586eb8b24d16d051dd0cd3d4655e 342 SUPERFAMILY SSF46955 3 102 2.45E-23 T 28-03-2018 IPR009061 Putative DNA-binding domain CU254_RS06890 3484586eb8b24d16d051dd0cd3d4655e 342 SUPERFAMILY SSF48371 116 322 2.21E-17 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 CU254_RS06890 3484586eb8b24d16d051dd0cd3d4655e 342 Gene3D G3DSA:1.10.1660.10 1 56 1.1E-19 T 28-03-2018 CU254_RS06890 3484586eb8b24d16d051dd0cd3d4655e 342 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 2.0E-7 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS06890 3484586eb8b24d16d051dd0cd3d4655e 342 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 2.0E-7 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS06890 3484586eb8b24d16d051dd0cd3d4655e 342 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 2.0E-7 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS06890 3484586eb8b24d16d051dd0cd3d4655e 342 Gene3D G3DSA:1.10.1660.10 57 137 7.4E-5 T 28-03-2018 CU254_RS06890 3484586eb8b24d16d051dd0cd3d4655e 342 Gene3D G3DSA:1.25.40.70 145 232 5.4E-8 T 28-03-2018 CU254_RS06890 3484586eb8b24d16d051dd0cd3d4655e 342 SMART SM00567 E-Z type HEAT repeats 189 218 42.0 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CU254_RS06890 3484586eb8b24d16d051dd0cd3d4655e 342 SMART SM00567 E-Z type HEAT repeats 285 314 440.0 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CU254_RS06890 3484586eb8b24d16d051dd0cd3d4655e 342 SMART SM00567 E-Z type HEAT repeats 220 249 9.4 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CU254_RS06890 3484586eb8b24d16d051dd0cd3d4655e 342 Pfam PF13646 HEAT repeats 184 256 2.3E-9 T 28-03-2018 CU254_RS00750 bfd3e9e94d87009c1ef56caa5c98cd10 212 Pfam PF12680 SnoaL-like domain 93 196 1.3E-17 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CU254_RS00750 bfd3e9e94d87009c1ef56caa5c98cd10 212 SUPERFAMILY SSF54427 89 206 5.92E-25 T 28-03-2018 IPR032710 NTF2-like domain CU254_RS00750 bfd3e9e94d87009c1ef56caa5c98cd10 212 Gene3D G3DSA:3.10.450.50 90 212 2.6E-25 T 28-03-2018 CU254_RS04780 5708dc82e4e4e6ecc410a693b4d19554 265 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 11 137 3.2E-9 T 28-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CU254_RS04780 5708dc82e4e4e6ecc410a693b4d19554 265 SUPERFAMILY SSF55718 169 256 7.65E-5 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CU254_RS04780 5708dc82e4e4e6ecc410a693b4d19554 265 SUPERFAMILY SSF109854 12 141 2.38E-8 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CU254_RS04780 5708dc82e4e4e6ecc410a693b4d19554 265 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 16 233 1.1E-15 T 28-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CU254_RS04780 5708dc82e4e4e6ecc410a693b4d19554 265 Gene3D G3DSA:1.20.120.450 5 143 6.6E-13 T 28-03-2018 CU254_RS04780 5708dc82e4e4e6ecc410a693b4d19554 265 Gene3D G3DSA:3.30.1050.10 162 260 1.4E-6 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CU254_RS18155 b80330c4e02d051b690f268b93de1418 281 Hamap MF_00079 ATP phosphoribosyltransferase [hisG]. 1 281 31.365 T 28-03-2018 IPR020621 ATP phosphoribosyltransferase HisG, long form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 CU254_RS18155 b80330c4e02d051b690f268b93de1418 281 Gene3D G3DSA:3.30.70.120 209 273 1.5E-25 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CU254_RS18155 b80330c4e02d051b690f268b93de1418 281 Gene3D G3DSA:3.40.190.10 115 208 1.4E-18 T 28-03-2018 CU254_RS18155 b80330c4e02d051b690f268b93de1418 281 SUPERFAMILY SSF53850 1 207 7.61E-62 T 28-03-2018 CU254_RS18155 b80330c4e02d051b690f268b93de1418 281 Pfam PF01634 ATP phosphoribosyltransferase 49 202 2.1E-40 T 28-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 CU254_RS18155 b80330c4e02d051b690f268b93de1418 281 SUPERFAMILY SSF54913 209 280 7.11E-22 T 28-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta CU254_RS18155 b80330c4e02d051b690f268b93de1418 281 TIGRFAM TIGR03455 HisG_C-term: ATP phosphoribosyltransferase, C-terminal domain 193 280 1.2E-29 T 28-03-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 CU254_RS18155 b80330c4e02d051b690f268b93de1418 281 Gene3D G3DSA:3.40.190.10 1 114 7.9E-35 T 28-03-2018 CU254_RS18155 b80330c4e02d051b690f268b93de1418 281 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 2 182 2.9E-50 T 28-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 CU254_RS18155 b80330c4e02d051b690f268b93de1418 281 Pfam PF08029 HisG, C-terminal domain 206 277 1.8E-26 T 28-03-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 CU254_RS11615 a136f4d2768ddf9712729a85af486a21 265 Gene3D G3DSA:3.60.10.10 2 261 7.5E-48 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CU254_RS11615 a136f4d2768ddf9712729a85af486a21 265 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 29 38 - T 28-03-2018 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 CU254_RS11615 a136f4d2768ddf9712729a85af486a21 265 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 6 252 8.1E-21 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CU254_RS11615 a136f4d2768ddf9712729a85af486a21 265 SUPERFAMILY SSF56219 4 261 1.57E-67 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CU254_RS11615 a136f4d2768ddf9712729a85af486a21 265 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 4 258 5.1E-59 T 28-03-2018 CU254_RS11615 a136f4d2768ddf9712729a85af486a21 265 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 4 259 1.6E-75 T 28-03-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 CU254_RS16915 a70e9e799e8ff11e0a82e11e739d74e6 523 SUPERFAMILY SSF56645 18 285 9.46E-86 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS16915 a70e9e799e8ff11e0a82e11e739d74e6 523 Gene3D G3DSA:2.40.110.10 157 286 2.1E-14 T 28-03-2018 CU254_RS16915 a70e9e799e8ff11e0a82e11e739d74e6 523 Gene3D G3DSA:1.10.3140.10 19 156 1.6E-54 T 28-03-2018 CU254_RS16915 a70e9e799e8ff11e0a82e11e739d74e6 523 PIRSF PIRSF000331 16 504 1.9E-206 T 28-03-2018 IPR004925 HpaB/PvcC/4-BUDH CU254_RS16915 a70e9e799e8ff11e0a82e11e739d74e6 523 SUPERFAMILY SSF47203 275 492 1.69E-48 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS16915 a70e9e799e8ff11e0a82e11e739d74e6 523 Pfam PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal 20 284 2.8E-97 T 28-03-2018 IPR024674 HpaB/PvcC/4-BUDH N-terminal CU254_RS16915 a70e9e799e8ff11e0a82e11e739d74e6 523 Pfam PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal 292 492 5.4E-67 T 28-03-2018 IPR024719 HpaB/PvcC/4-BUDH C-terminal CU254_RS16915 a70e9e799e8ff11e0a82e11e739d74e6 523 Gene3D G3DSA:1.20.140.10 295 493 1.3E-65 T 28-03-2018 CU254_RS16915 a70e9e799e8ff11e0a82e11e739d74e6 523 PIRSF PIRSF500125 4 521 8.1E-263 T 28-03-2018 IPR024677 4-HPA 3-monooxygenase large component/Pyoverdin chromophore biosynthetic protein CU254_RS28450 2c21bce742e897060738e00526cdc2a8 492 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 4 230 6.2E-24 T 28-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CU254_RS28450 2c21bce742e897060738e00526cdc2a8 492 SUPERFAMILY SSF52317 264 415 1.06E-34 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS28450 2c21bce742e897060738e00526cdc2a8 492 SUPERFAMILY SSF52317 191 237 1.06E-34 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS28450 2c21bce742e897060738e00526cdc2a8 492 SUPERFAMILY SSF52540 1 237 6.45E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS28450 2c21bce742e897060738e00526cdc2a8 492 Gene3D G3DSA:3.40.50.880 241 469 1.3E-30 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS28450 2c21bce742e897060738e00526cdc2a8 492 Gene3D G3DSA:3.40.50.300 1 240 2.2E-52 T 28-03-2018 CU254_RS28450 2c21bce742e897060738e00526cdc2a8 492 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 479 164.77 T 28-03-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 CU254_RS28450 2c21bce742e897060738e00526cdc2a8 492 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 252 421 6.4E-39 T 28-03-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 CU254_RS28450 2c21bce742e897060738e00526cdc2a8 492 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 5 471 3.9E-131 T 28-03-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 CU254_RS31950 8d50c4af4ef671e2f9d8f302007d627e 409 Pfam PF07690 Major Facilitator Superfamily 20 343 6.6E-21 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS31950 8d50c4af4ef671e2f9d8f302007d627e 409 Gene3D G3DSA:1.20.1250.20 1 196 4.8E-15 T 28-03-2018 CU254_RS31950 8d50c4af4ef671e2f9d8f302007d627e 409 Gene3D G3DSA:1.20.1250.20 211 401 1.5E-15 T 28-03-2018 CU254_RS31950 8d50c4af4ef671e2f9d8f302007d627e 409 SUPERFAMILY SSF103473 8 391 8.24E-35 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS33835 82c66d31a2a227549ef8b0aa82c25de3 280 SMART SM00650 35 210 6.6E-66 T 28-03-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 CU254_RS33835 82c66d31a2a227549ef8b0aa82c25de3 280 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 51 78 - T 28-03-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 CU254_RS33835 82c66d31a2a227549ef8b0aa82c25de3 280 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 19 280 49.328 T 28-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 CU254_RS33835 82c66d31a2a227549ef8b0aa82c25de3 280 Pfam PF00398 Ribosomal RNA adenine dimethylase 23 276 6.8E-44 T 28-03-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm CU254_RS33835 82c66d31a2a227549ef8b0aa82c25de3 280 Gene3D G3DSA:1.10.8.100 219 280 2.1E-21 T 28-03-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 CU254_RS33835 82c66d31a2a227549ef8b0aa82c25de3 280 SUPERFAMILY SSF53335 19 277 1.35E-64 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS33835 82c66d31a2a227549ef8b0aa82c25de3 280 Gene3D G3DSA:3.40.50.150 15 218 6.9E-49 T 28-03-2018 CU254_RS33835 82c66d31a2a227549ef8b0aa82c25de3 280 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 19 277 1.1E-72 T 28-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 CU254_RS07545 a5bad545cc60ca5bad3a234702359e80 251 Gene3D G3DSA:3.40.1080.10 1 250 2.9E-55 T 28-03-2018 CU254_RS07545 a5bad545cc60ca5bad3a234702359e80 251 SUPERFAMILY SSF100950 2 246 2.23E-72 T 28-03-2018 CU254_RS07545 a5bad545cc60ca5bad3a234702359e80 251 Pfam PF01144 Coenzyme A transferase 8 218 7.4E-42 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CU254_RS07545 a5bad545cc60ca5bad3a234702359e80 251 SMART SM00882 8 218 5.0E-39 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CU254_RS31345 fd3f9f4c52f9191850295a679d3e6991 279 Gene3D G3DSA:3.20.20.30 20 277 2.1E-54 T 28-03-2018 CU254_RS31345 fd3f9f4c52f9191850295a679d3e6991 279 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 43 260 2.2E-54 T 28-03-2018 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted CU254_RS31345 fd3f9f4c52f9191850295a679d3e6991 279 Pfam PF00296 Luciferase-like monooxygenase 35 224 7.1E-47 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS31345 fd3f9f4c52f9191850295a679d3e6991 279 SUPERFAMILY SSF51679 21 271 5.59E-52 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS24300 48c2c3739d7f52077abb91834130d039 155 SMART SM00422 9 77 4.5E-23 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS24300 48c2c3739d7f52077abb91834130d039 155 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 44 64 9.3E-10 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS24300 48c2c3739d7f52077abb91834130d039 155 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 10 21 9.3E-10 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS24300 48c2c3739d7f52077abb91834130d039 155 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 21 34 9.3E-10 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS24300 48c2c3739d7f52077abb91834130d039 155 Gene3D G3DSA:1.10.1660.10 5 63 9.0E-19 T 28-03-2018 CU254_RS24300 48c2c3739d7f52077abb91834130d039 155 TIGRFAM TIGR01950 SoxR: redox-sensitive transcriptional activator SoxR 8 148 5.0E-63 T 28-03-2018 IPR010211 Redox-sensitive transcriptional activator SoxR GO:0003677|GO:0006355|GO:0006979|GO:0051537 CU254_RS24300 48c2c3739d7f52077abb91834130d039 155 SUPERFAMILY SSF46955 9 131 4.03E-30 T 28-03-2018 IPR009061 Putative DNA-binding domain CU254_RS24300 48c2c3739d7f52077abb91834130d039 155 Pfam PF00376 MerR family regulatory protein 10 46 1.1E-12 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS24300 48c2c3739d7f52077abb91834130d039 155 Gene3D G3DSA:1.10.1660.10 64 139 1.2E-15 T 28-03-2018 CU254_RS24300 48c2c3739d7f52077abb91834130d039 155 Pfam PF09278 MerR, DNA binding 51 116 2.9E-20 T 28-03-2018 IPR015358 Transcription regulator MerR, DNA binding CU254_RS02640 72853ee5d30dc78d059532b52f3ab464 501 Pfam PF00817 impB/mucB/samB family 5 119 1.9E-11 T 28-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CU254_RS02640 72853ee5d30dc78d059532b52f3ab464 501 Gene3D G3DSA:1.10.150.20 127 203 3.2E-11 T 28-03-2018 CU254_RS02640 72853ee5d30dc78d059532b52f3ab464 501 Gene3D G3DSA:3.30.70.270 7 68 9.4E-4 T 28-03-2018 CU254_RS02640 72853ee5d30dc78d059532b52f3ab464 501 SUPERFAMILY SSF56672 5 197 1.25E-29 T 28-03-2018 CU254_RS28370 ba057a1347d9ce4fde2be9e9ff829032 402 PRINTS PR00385 P450 superfamily signature 240 257 4.2E-8 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS28370 ba057a1347d9ce4fde2be9e9ff829032 402 PRINTS PR00385 P450 superfamily signature 272 283 4.2E-8 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS28370 ba057a1347d9ce4fde2be9e9ff829032 402 PRINTS PR00385 P450 superfamily signature 349 360 4.2E-8 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS28370 ba057a1347d9ce4fde2be9e9ff829032 402 PRINTS PR00385 P450 superfamily signature 340 349 4.2E-8 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS28370 ba057a1347d9ce4fde2be9e9ff829032 402 Pfam PF00067 Cytochrome P450 273 369 5.5E-17 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS28370 ba057a1347d9ce4fde2be9e9ff829032 402 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 342 351 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CU254_RS28370 ba057a1347d9ce4fde2be9e9ff829032 402 SUPERFAMILY SSF48264 17 400 7.73E-88 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS28370 ba057a1347d9ce4fde2be9e9ff829032 402 PRINTS PR00359 B-class P450 signature 139 155 3.7E-51 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS28370 ba057a1347d9ce4fde2be9e9ff829032 402 PRINTS PR00359 B-class P450 signature 349 360 3.7E-51 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS28370 ba057a1347d9ce4fde2be9e9ff829032 402 PRINTS PR00359 B-class P450 signature 272 283 3.7E-51 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS28370 ba057a1347d9ce4fde2be9e9ff829032 402 PRINTS PR00359 B-class P450 signature 193 215 3.7E-51 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS28370 ba057a1347d9ce4fde2be9e9ff829032 402 PRINTS PR00359 B-class P450 signature 156 171 3.7E-51 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS28370 ba057a1347d9ce4fde2be9e9ff829032 402 PRINTS PR00359 B-class P450 signature 340 349 3.7E-51 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS28370 ba057a1347d9ce4fde2be9e9ff829032 402 PRINTS PR00359 B-class P450 signature 290 317 3.7E-51 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS28370 ba057a1347d9ce4fde2be9e9ff829032 402 PRINTS PR00359 B-class P450 signature 92 103 3.7E-51 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS28370 ba057a1347d9ce4fde2be9e9ff829032 402 PRINTS PR00359 B-class P450 signature 318 333 3.7E-51 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS28370 ba057a1347d9ce4fde2be9e9ff829032 402 Gene3D G3DSA:1.10.630.10 15 402 3.6E-69 T 28-03-2018 CU254_RS08320 d1a54e40cba40eb75dfb640ef0b96299 158 Gene3D G3DSA:2.30.110.10 3 158 9.9E-37 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS08320 d1a54e40cba40eb75dfb640ef0b96299 158 Pfam PF04075 F420H(2)-dependent quinone reductase 48 156 3.0E-28 T 28-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CU254_RS08320 d1a54e40cba40eb75dfb640ef0b96299 158 SUPERFAMILY SSF50475 62 150 1.13E-5 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS08320 d1a54e40cba40eb75dfb640ef0b96299 158 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 48 156 2.6E-27 T 28-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CU254_RS05580 0a63f8eb72b88db3beb13275593cb3b8 196 Pfam PF00574 Clp protease 15 194 2.2E-63 T 28-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA CU254_RS05580 0a63f8eb72b88db3beb13275593cb3b8 196 SUPERFAMILY SSF52096 5 194 6.17E-55 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS05580 0a63f8eb72b88db3beb13275593cb3b8 196 Gene3D G3DSA:3.90.226.10 4 196 1.2E-34 T 28-03-2018 CU254_RS05580 0a63f8eb72b88db3beb13275593cb3b8 196 PRINTS PR00127 Clp protease catalytic subunit P signature 113 132 1.2E-35 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CU254_RS05580 0a63f8eb72b88db3beb13275593cb3b8 196 PRINTS PR00127 Clp protease catalytic subunit P signature 21 36 1.2E-35 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CU254_RS05580 0a63f8eb72b88db3beb13275593cb3b8 196 PRINTS PR00127 Clp protease catalytic subunit P signature 170 189 1.2E-35 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CU254_RS05580 0a63f8eb72b88db3beb13275593cb3b8 196 PRINTS PR00127 Clp protease catalytic subunit P signature 92 109 1.2E-35 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CU254_RS05580 0a63f8eb72b88db3beb13275593cb3b8 196 PRINTS PR00127 Clp protease catalytic subunit P signature 61 81 1.2E-35 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CU254_RS05580 0a63f8eb72b88db3beb13275593cb3b8 196 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 5 195 34.837 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CU254_RS23525 b16c59c833a3fa69b3acd1975151f687 954 SUPERFAMILY SSF55103 272 516 5.89E-51 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CU254_RS23525 b16c59c833a3fa69b3acd1975151f687 954 Pfam PF02913 FAD linked oxidases, C-terminal domain 269 513 1.9E-50 T 28-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CU254_RS23525 b16c59c833a3fa69b3acd1975151f687 954 Pfam PF02754 Cysteine-rich domain 731 803 0.0011 T 28-03-2018 IPR004017 Cysteine-rich domain CU254_RS23525 b16c59c833a3fa69b3acd1975151f687 954 Gene3D G3DSA:3.30.465.10 94 289 7.5E-42 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CU254_RS23525 b16c59c833a3fa69b3acd1975151f687 954 Pfam PF01565 FAD binding domain 44 181 1.9E-39 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CU254_RS23525 b16c59c833a3fa69b3acd1975151f687 954 Pfam PF13183 4Fe-4S dicluster domain 552 628 9.3E-11 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CU254_RS23525 b16c59c833a3fa69b3acd1975151f687 954 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 614 625 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CU254_RS23525 b16c59c833a3fa69b3acd1975151f687 954 Gene3D G3DSA:3.30.43.10 2 93 3.1E-21 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CU254_RS23525 b16c59c833a3fa69b3acd1975151f687 954 SUPERFAMILY SSF46548 552 632 1.15E-9 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CU254_RS23525 b16c59c833a3fa69b3acd1975151f687 954 SUPERFAMILY SSF56176 9 269 2.94E-57 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CU254_RS23525 b16c59c833a3fa69b3acd1975151f687 954 Gene3D G3DSA:1.10.1060.10 536 649 1.8E-17 T 28-03-2018 CU254_RS23525 b16c59c833a3fa69b3acd1975151f687 954 Gene3D G3DSA:1.10.45.10 474 513 7.8E-7 T 28-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CU254_RS24025 39e6c31f4accc00f0e908f275cf6978b 274 SUPERFAMILY SSF55781 79 260 3.92E-34 T 28-03-2018 IPR029016 GAF domain-like CU254_RS24025 39e6c31f4accc00f0e908f275cf6978b 274 SUPERFAMILY SSF46785 26 89 2.27E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS24025 39e6c31f4accc00f0e908f275cf6978b 274 Pfam PF09339 IclR helix-turn-helix domain 26 73 2.5E-12 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS24025 39e6c31f4accc00f0e908f275cf6978b 274 Pfam PF01614 Bacterial transcriptional regulator 141 257 7.9E-21 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal CU254_RS24025 39e6c31f4accc00f0e908f275cf6978b 274 Gene3D G3DSA:3.30.450.40 87 265 5.7E-40 T 28-03-2018 IPR029016 GAF domain-like CU254_RS24025 39e6c31f4accc00f0e908f275cf6978b 274 SMART SM00346 23 111 8.3E-10 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS24025 39e6c31f4accc00f0e908f275cf6978b 274 Gene3D G3DSA:1.10.10.10 23 78 3.0E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS31895 92cb2f2814580cb7beedcb7376b8ed0d 353 SUPERFAMILY SSF75011 81 337 8.11E-6 T 28-03-2018 CU254_RS31895 92cb2f2814580cb7beedcb7376b8ed0d 353 Gene3D G3DSA:2.130.10.10 41 339 1.0E-7 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CU254_RS31895 92cb2f2814580cb7beedcb7376b8ed0d 353 Pfam PF13449 Esterase-like activity of phytase 73 291 7.4E-7 T 28-03-2018 IPR027372 Phytase-like domain CU254_RS18710 df147e12c5810c1a4249e5c823330865 389 Gene3D G3DSA:1.10.540.10 2 121 2.2E-29 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS18710 df147e12c5810c1a4249e5c823330865 389 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 233 377 6.3E-45 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS18710 df147e12c5810c1a4249e5c823330865 389 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 10 119 1.3E-27 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS18710 df147e12c5810c1a4249e5c823330865 389 SUPERFAMILY SSF47203 231 383 7.73E-51 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS18710 df147e12c5810c1a4249e5c823330865 389 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 339 358 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CU254_RS18710 df147e12c5810c1a4249e5c823330865 389 SUPERFAMILY SSF56645 7 244 1.1E-75 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS18710 df147e12c5810c1a4249e5c823330865 389 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 219 3.5E-28 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CU254_RS18710 df147e12c5810c1a4249e5c823330865 389 PIRSF PIRSF016578 130 373 3.9E-11 T 28-03-2018 CU254_RS18710 df147e12c5810c1a4249e5c823330865 389 PIRSF PIRSF016578 1 83 0.017 T 28-03-2018 CU254_RS18710 df147e12c5810c1a4249e5c823330865 389 Gene3D G3DSA:1.20.140.10 221 389 3.4E-54 T 28-03-2018 CU254_RS18710 df147e12c5810c1a4249e5c823330865 389 Gene3D G3DSA:2.40.110.10 122 220 1.1E-38 T 28-03-2018 CU254_RS13690 cbdd4ba9a77b6b981108656ee79f3a76 293 Gene3D G3DSA:3.30.1780.10 3 127 3.9E-41 T 28-03-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 CU254_RS13690 cbdd4ba9a77b6b981108656ee79f3a76 293 SUPERFAMILY SSF51735 9 292 7.9E-73 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS13690 cbdd4ba9a77b6b981108656ee79f3a76 293 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 23 292 1.7E-49 T 28-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CU254_RS13690 cbdd4ba9a77b6b981108656ee79f3a76 293 Gene3D G3DSA:3.40.50.720 128 276 1.9E-26 T 28-03-2018 CU254_RS13690 cbdd4ba9a77b6b981108656ee79f3a76 293 PIRSF PIRSF001439 2 293 1.1E-61 T 28-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CU254_RS30155 0e7bfe2b67b2512f5ae62eaa29c94d4b 422 PIRSF PIRSF001495 1 415 4.5E-132 T 28-03-2018 IPR006396 Glutamate mutase epsilon subunit GO:0019670|GO:0050097 KEGG: 00630+5.4.99.1|KEGG: 00660+5.4.99.1|MetaCyc: PWY-5087|MetaCyc: PWY-5103|MetaCyc: PWY-6728 CU254_RS30155 0e7bfe2b67b2512f5ae62eaa29c94d4b 422 Gene3D G3DSA:3.20.20.240 1 356 5.0E-91 T 28-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CU254_RS30155 0e7bfe2b67b2512f5ae62eaa29c94d4b 422 SUPERFAMILY SSF51703 3 403 7.14E-113 T 28-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CU254_RS30155 0e7bfe2b67b2512f5ae62eaa29c94d4b 422 Pfam PF06368 Methylaspartate mutase E chain (MutE) 3 383 2.9E-85 T 28-03-2018 IPR006396 Glutamate mutase epsilon subunit GO:0019670|GO:0050097 KEGG: 00630+5.4.99.1|KEGG: 00660+5.4.99.1|MetaCyc: PWY-5087|MetaCyc: PWY-5103|MetaCyc: PWY-6728 CU254_RS15350 a36b1c70d2b27a7290420ed57686b3db 391 Gene3D G3DSA:1.20.1090.10 193 391 3.3E-54 T 28-03-2018 CU254_RS15350 a36b1c70d2b27a7290420ed57686b3db 391 Pfam PF00465 Iron-containing alcohol dehydrogenase 18 383 2.6E-106 T 28-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 CU254_RS15350 a36b1c70d2b27a7290420ed57686b3db 391 Gene3D G3DSA:3.40.50.1970 16 191 3.7E-42 T 28-03-2018 CU254_RS15350 a36b1c70d2b27a7290420ed57686b3db 391 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 268 288 - T 28-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 CU254_RS15350 a36b1c70d2b27a7290420ed57686b3db 391 SUPERFAMILY SSF56796 18 390 4.71E-105 T 28-03-2018 CU254_RS05725 8cb9c5d7db4d9fb003e6df0bc05e7740 202 Pfam PF01427 D-ala-D-ala dipeptidase 4 199 2.4E-63 T 28-03-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 CU254_RS05725 8cb9c5d7db4d9fb003e6df0bc05e7740 202 SUPERFAMILY SSF55166 2 199 2.55E-68 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CU254_RS05725 8cb9c5d7db4d9fb003e6df0bc05e7740 202 Gene3D G3DSA:3.30.1380.10 1 202 1.7E-59 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CU254_RS05725 8cb9c5d7db4d9fb003e6df0bc05e7740 202 PIRSF PIRSF026671 2 202 8.1E-59 T 28-03-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 CU254_RS05725 8cb9c5d7db4d9fb003e6df0bc05e7740 202 Hamap MF_01924 D-alanyl-D-alanine dipeptidase [ddpX]. 4 200 29.259 T 28-03-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 CU254_RS06565 dadbabaeb994c494ec136b5396045cd3 287 SUPERFAMILY SSF51735 13 186 1.13E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS06565 dadbabaeb994c494ec136b5396045cd3 287 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 15 184 1.0E-32 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CU254_RS06565 dadbabaeb994c494ec136b5396045cd3 287 Gene3D G3DSA:3.40.50.720 7 190 4.1E-32 T 28-03-2018 CU254_RS06565 dadbabaeb994c494ec136b5396045cd3 287 SUPERFAMILY SSF48179 190 286 4.85E-25 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CU254_RS06565 dadbabaeb994c494ec136b5396045cd3 287 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 190 286 1.9E-24 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CU254_RS06565 dadbabaeb994c494ec136b5396045cd3 287 Gene3D G3DSA:1.10.1040.10 191 287 2.4E-26 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CU254_RS06565 dadbabaeb994c494ec136b5396045cd3 287 PIRSF PIRSF000105 8 287 3.0E-71 T 28-03-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 CU254_RS29135 745f741809d0390784baecb04a4c3b27 289 SMART SM00530 9 82 5.5E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS29135 745f741809d0390784baecb04a4c3b27 289 SUPERFAMILY SSF47413 30 81 7.11E-9 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS29135 745f741809d0390784baecb04a4c3b27 289 Pfam PF13560 Helix-turn-helix domain 6 85 6.1E-15 T 28-03-2018 CU254_RS29135 745f741809d0390784baecb04a4c3b27 289 Gene3D G3DSA:1.10.260.40 4 101 2.3E-14 T 28-03-2018 CU254_RS32525 7188ecaed5ff8f043f73772b5794c658 490 Gene3D G3DSA:3.40.50.1480 2 262 7.1E-110 T 28-03-2018 CU254_RS32525 7188ecaed5ff8f043f73772b5794c658 490 SMART SM00996 17 489 0.0 T 28-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CU254_RS32525 7188ecaed5ff8f043f73772b5794c658 490 PIRSF PIRSF001109 4 490 3.2E-190 T 28-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CU254_RS32525 7188ecaed5ff8f043f73772b5794c658 490 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 17 489 1.2E-146 T 28-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CU254_RS32525 7188ecaed5ff8f043f73772b5794c658 490 Gene3D G3DSA:3.40.50.1480 263 463 4.2E-82 T 28-03-2018 CU254_RS32525 7188ecaed5ff8f043f73772b5794c658 490 SMART SM00997 248 410 2.3E-106 T 28-03-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CU254_RS32525 7188ecaed5ff8f043f73772b5794c658 490 SUPERFAMILY SSF51735 248 410 3.26E-76 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS32525 7188ecaed5ff8f043f73772b5794c658 490 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 89 103 - T 28-03-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CU254_RS32525 7188ecaed5ff8f043f73772b5794c658 490 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 270 286 - T 28-03-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CU254_RS32525 7188ecaed5ff8f043f73772b5794c658 490 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 248 410 3.6E-80 T 28-03-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CU254_RS32525 7188ecaed5ff8f043f73772b5794c658 490 SUPERFAMILY SSF52283 200 247 2.27E-112 T 28-03-2018 CU254_RS32525 7188ecaed5ff8f043f73772b5794c658 490 SUPERFAMILY SSF52283 411 490 2.27E-112 T 28-03-2018 CU254_RS32525 7188ecaed5ff8f043f73772b5794c658 490 SUPERFAMILY SSF52283 17 162 2.27E-112 T 28-03-2018 CU254_RS32525 7188ecaed5ff8f043f73772b5794c658 490 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 13 482 48.459 T 28-03-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508 CU254_RS32525 7188ecaed5ff8f043f73772b5794c658 490 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 18 482 3.2E-192 T 28-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CU254_RS37655 5526dbd3d17cad9d0cb944d3972998b2 544 SUPERFAMILY SSF90123 19 339 3.66E-50 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CU254_RS37655 5526dbd3d17cad9d0cb944d3972998b2 544 ProSitePatterns PS00211 ABC transporters family signature. 469 483 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS37655 5526dbd3d17cad9d0cb944d3972998b2 544 SUPERFAMILY SSF52540 376 537 5.59E-32 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS37655 5526dbd3d17cad9d0cb944d3972998b2 544 Pfam PF00664 ABC transporter transmembrane region 48 303 9.9E-26 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CU254_RS37655 5526dbd3d17cad9d0cb944d3972998b2 544 Pfam PF00005 ABC transporter 381 497 6.3E-11 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS37655 5526dbd3d17cad9d0cb944d3972998b2 544 Gene3D G3DSA:1.20.1560.10 18 336 1.6E-44 T 28-03-2018 CU254_RS37655 5526dbd3d17cad9d0cb944d3972998b2 544 Gene3D G3DSA:3.40.50.300 401 540 1.2E-28 T 28-03-2018 CU254_RS08045 03abf75e0dacc6506f2c3c55fbafc524 297 Gene3D G3DSA:3.40.50.10490 5 291 2.2E-99 T 28-03-2018 CU254_RS08045 03abf75e0dacc6506f2c3c55fbafc524 297 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 28-03-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 CU254_RS08045 03abf75e0dacc6506f2c3c55fbafc524 297 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 224 2.2E-108 T 28-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS08045 03abf75e0dacc6506f2c3c55fbafc524 297 Pfam PF00318 Ribosomal protein S2 9 224 7.4E-97 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS08045 03abf75e0dacc6506f2c3c55fbafc524 297 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 231 42.178 T 28-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS08045 03abf75e0dacc6506f2c3c55fbafc524 297 SUPERFAMILY SSF52313 6 226 1.02E-93 T 28-03-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain CU254_RS08045 03abf75e0dacc6506f2c3c55fbafc524 297 PRINTS PR00395 Ribosomal protein S2 signature 6 24 2.2E-39 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS08045 03abf75e0dacc6506f2c3c55fbafc524 297 PRINTS PR00395 Ribosomal protein S2 signature 37 46 2.2E-39 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS08045 03abf75e0dacc6506f2c3c55fbafc524 297 PRINTS PR00395 Ribosomal protein S2 signature 87 104 2.2E-39 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS08045 03abf75e0dacc6506f2c3c55fbafc524 297 PRINTS PR00395 Ribosomal protein S2 signature 196 210 2.2E-39 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS08045 03abf75e0dacc6506f2c3c55fbafc524 297 PRINTS PR00395 Ribosomal protein S2 signature 158 175 2.2E-39 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS08045 03abf75e0dacc6506f2c3c55fbafc524 297 PRINTS PR00395 Ribosomal protein S2 signature 175 186 2.2E-39 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS40755 710535dcaf59f75763d8b3a3490dc44f 1237 Gene3D G3DSA:3.40.50.200 184 491 7.9E-85 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS40755 710535dcaf59f75763d8b3a3490dc44f 1237 Pfam PF00082 Subtilase family 217 481 8.1E-57 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS40755 710535dcaf59f75763d8b3a3490dc44f 1237 SUPERFAMILY SSF52743 199 490 1.7E-77 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS40755 710535dcaf59f75763d8b3a3490dc44f 1237 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 433 443 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CU254_RS40755 710535dcaf59f75763d8b3a3490dc44f 1237 Gene3D G3DSA:2.60.40.10 495 610 6.8E-6 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS40755 710535dcaf59f75763d8b3a3490dc44f 1237 Gene3D G3DSA:3.50.30.30 750 910 2.1E-9 T 28-03-2018 CU254_RS40755 710535dcaf59f75763d8b3a3490dc44f 1237 Pfam PF02225 PA domain 798 868 3.5E-6 T 28-03-2018 IPR003137 PA domain CU254_RS40755 710535dcaf59f75763d8b3a3490dc44f 1237 PRINTS PR00723 Subtilisin serine protease family (S8) signature 254 267 2.8E-20 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CU254_RS40755 710535dcaf59f75763d8b3a3490dc44f 1237 PRINTS PR00723 Subtilisin serine protease family (S8) signature 217 236 2.8E-20 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CU254_RS40755 710535dcaf59f75763d8b3a3490dc44f 1237 PRINTS PR00723 Subtilisin serine protease family (S8) signature 432 448 2.8E-20 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CU254_RS01625 180bc72381d25af60d07fcb24f4bf7d6 103 Pfam PF07110 EthD domain 13 88 1.9E-8 T 28-03-2018 IPR009799 EthD domain CU254_RS01625 180bc72381d25af60d07fcb24f4bf7d6 103 Gene3D G3DSA:3.30.70.100 1 95 2.1E-25 T 28-03-2018 CU254_RS01625 180bc72381d25af60d07fcb24f4bf7d6 103 TIGRFAM TIGR02118 TIGR02118: conserved hypothetical protein 1 93 7.9E-23 T 28-03-2018 IPR009799 EthD domain CU254_RS01625 180bc72381d25af60d07fcb24f4bf7d6 103 SUPERFAMILY SSF54909 1 94 4.1E-26 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS07095 426c499a55d82a100b3b3603e90faf35 456 SUPERFAMILY SSF53383 78 455 1.22E-66 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS07095 426c499a55d82a100b3b3603e90faf35 456 SUPERFAMILY SSF46785 14 87 3.67E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS07095 426c499a55d82a100b3b3603e90faf35 456 Gene3D G3DSA:3.90.1150.10 363 456 9.9E-14 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS07095 426c499a55d82a100b3b3603e90faf35 456 Pfam PF00392 Bacterial regulatory proteins, gntR family 21 83 1.2E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS07095 426c499a55d82a100b3b3603e90faf35 456 SMART SM00345 24 83 6.2E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS07095 426c499a55d82a100b3b3603e90faf35 456 Gene3D G3DSA:3.40.640.10 124 362 7.5E-34 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS07095 426c499a55d82a100b3b3603e90faf35 456 Gene3D G3DSA:1.10.10.10 7 85 5.5E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS07095 426c499a55d82a100b3b3603e90faf35 456 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 57 73 2.0E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS07095 426c499a55d82a100b3b3603e90faf35 456 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 57 2.0E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS07095 426c499a55d82a100b3b3603e90faf35 456 Pfam PF00155 Aminotransferase class I and II 144 402 7.3E-13 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CU254_RS05760 f81f757285e3c51b82bc31f4ef30054d 218 Gene3D G3DSA:1.10.10.10 131 217 1.6E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS05760 f81f757285e3c51b82bc31f4ef30054d 218 SUPERFAMILY SSF46894 143 211 5.1E-20 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS05760 f81f757285e3c51b82bc31f4ef30054d 218 Gene3D G3DSA:3.40.50.2300 5 130 8.8E-40 T 28-03-2018 CU254_RS05760 f81f757285e3c51b82bc31f4ef30054d 218 SUPERFAMILY SSF52172 5 136 1.71E-35 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS05760 f81f757285e3c51b82bc31f4ef30054d 218 Pfam PF00072 Response regulator receiver domain 9 119 2.8E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS05760 f81f757285e3c51b82bc31f4ef30054d 218 ProSitePatterns PS00622 LuxR-type HTH domain signature. 168 195 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS05760 f81f757285e3c51b82bc31f4ef30054d 218 SMART SM00421 151 208 1.0E-23 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS05760 f81f757285e3c51b82bc31f4ef30054d 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 184 2.1E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS05760 f81f757285e3c51b82bc31f4ef30054d 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 168 2.1E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS05760 f81f757285e3c51b82bc31f4ef30054d 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 196 2.1E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS05760 f81f757285e3c51b82bc31f4ef30054d 218 SMART SM00448 6 119 7.6E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS05760 f81f757285e3c51b82bc31f4ef30054d 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 208 1.9E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS30200 844a8b1ebfed7bc4d9f443430290d676 371 Pfam PF07730 Histidine kinase 180 247 2.9E-12 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CU254_RS30200 844a8b1ebfed7bc4d9f443430290d676 371 Pfam PF13796 Putative sensor 14 135 3.8E-24 T 28-03-2018 IPR025828 Putative sensor domain CU254_RS30200 844a8b1ebfed7bc4d9f443430290d676 371 Gene3D G3DSA:3.30.565.10 244 370 2.5E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS30200 844a8b1ebfed7bc4d9f443430290d676 371 SUPERFAMILY SSF55874 256 369 1.04E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS09790 f4b6428ec6b76fba21edcc3ec9b49177 185 SUPERFAMILY SSF48498 77 183 8.38E-22 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS09790 f4b6428ec6b76fba21edcc3ec9b49177 185 Gene3D G3DSA:1.10.357.10 55 185 3.1E-23 T 28-03-2018 CU254_RS09790 f4b6428ec6b76fba21edcc3ec9b49177 185 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 53 2.3E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS09790 f4b6428ec6b76fba21edcc3ec9b49177 185 SUPERFAMILY SSF46689 3 78 5.64E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS09790 f4b6428ec6b76fba21edcc3ec9b49177 185 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 105 182 1.6E-6 T 28-03-2018 CU254_RS09790 f4b6428ec6b76fba21edcc3ec9b49177 185 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 7 20 3.1E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS09790 f4b6428ec6b76fba21edcc3ec9b49177 185 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 51 3.1E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS09790 f4b6428ec6b76fba21edcc3ec9b49177 185 Gene3D G3DSA:1.10.10.60 1 54 4.3E-14 T 28-03-2018 CU254_RS08815 7e071fecf8c86cc3b3d80820b321cefe 355 Pfam PF02277 Phosphoribosyltransferase 13 350 1.2E-122 T 28-03-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CU254_RS08815 7e071fecf8c86cc3b3d80820b321cefe 355 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 18 350 2.7E-115 T 28-03-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CU254_RS08815 7e071fecf8c86cc3b3d80820b321cefe 355 Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. 15 352 34.011 T 28-03-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CU254_RS08815 7e071fecf8c86cc3b3d80820b321cefe 355 Gene3D G3DSA:3.40.50.10210 75 333 8.0E-96 T 28-03-2018 CU254_RS08815 7e071fecf8c86cc3b3d80820b321cefe 355 SUPERFAMILY SSF52733 12 351 8.89E-103 T 28-03-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CU254_RS08815 7e071fecf8c86cc3b3d80820b321cefe 355 Gene3D G3DSA:1.10.1610.10 9 74 1.3E-30 T 28-03-2018 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CU254_RS02325 93af3f8b035e627bbd3393570c3d36ce 221 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 3 205 2.0E-49 T 28-03-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 CU254_RS02325 93af3f8b035e627bbd3393570c3d36ce 221 SUPERFAMILY SSF53067 112 203 9.97E-11 T 28-03-2018 CU254_RS02325 93af3f8b035e627bbd3393570c3d36ce 221 SUPERFAMILY SSF53067 2 105 2.91E-19 T 28-03-2018 CU254_RS02325 93af3f8b035e627bbd3393570c3d36ce 221 Gene3D G3DSA:3.30.420.40 1 141 6.8E-33 T 28-03-2018 CU254_RS02325 93af3f8b035e627bbd3393570c3d36ce 221 Pfam PF00814 Glycoprotease family 36 138 1.0E-24 T 28-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CU254_RS32720 9a3aba9a31c6a0ae744f058f08e04a97 96 Gene3D G3DSA:3.30.1360.20 1 96 6.1E-28 T 28-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 CU254_RS32720 9a3aba9a31c6a0ae744f058f08e04a97 96 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 5 92 1.9E-26 T 28-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 CU254_RS32720 9a3aba9a31c6a0ae744f058f08e04a97 96 SUPERFAMILY SSF55248 1 93 1.57E-27 T 28-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 CU254_RS31080 29700a4cf70c0c9b995744b0295cf172 438 Pfam PF07690 Major Facilitator Superfamily 7 386 7.7E-44 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS31080 29700a4cf70c0c9b995744b0295cf172 438 SUPERFAMILY SSF103473 6 177 5.23E-56 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS31080 29700a4cf70c0c9b995744b0295cf172 438 SUPERFAMILY SSF103473 225 435 5.23E-56 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS31080 29700a4cf70c0c9b995744b0295cf172 438 Gene3D G3DSA:1.20.1250.20 229 438 3.1E-23 T 28-03-2018 CU254_RS31080 29700a4cf70c0c9b995744b0295cf172 438 PRINTS PR01036 Tetracycline resistance protein TetB signature 54 76 5.2E-5 T 28-03-2018 CU254_RS31080 29700a4cf70c0c9b995744b0295cf172 438 PRINTS PR01036 Tetracycline resistance protein TetB signature 115 139 5.2E-5 T 28-03-2018 CU254_RS31080 29700a4cf70c0c9b995744b0295cf172 438 PRINTS PR01036 Tetracycline resistance protein TetB signature 314 334 5.2E-5 T 28-03-2018 CU254_RS31080 29700a4cf70c0c9b995744b0295cf172 438 PRINTS PR01036 Tetracycline resistance protein TetB signature 377 396 5.2E-5 T 28-03-2018 CU254_RS31080 29700a4cf70c0c9b995744b0295cf172 438 Gene3D G3DSA:1.20.1250.20 1 177 9.4E-27 T 28-03-2018 CU254_RS20640 b842a98bcfda898a63bdc7b636b7ee94 417 SUPERFAMILY SSF55031 201 310 9.87E-13 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CU254_RS20640 b842a98bcfda898a63bdc7b636b7ee94 417 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 77 401 7.4E-70 T 28-03-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase CU254_RS20640 b842a98bcfda898a63bdc7b636b7ee94 417 Pfam PF07687 Peptidase dimerisation domain 201 309 7.9E-12 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CU254_RS20640 b842a98bcfda898a63bdc7b636b7ee94 417 Gene3D G3DSA:3.40.630.10 4 309 3.8E-60 T 28-03-2018 CU254_RS20640 b842a98bcfda898a63bdc7b636b7ee94 417 Pfam PF01546 Peptidase family M20/M25/M40 94 410 1.4E-38 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CU254_RS20640 b842a98bcfda898a63bdc7b636b7ee94 417 SUPERFAMILY SSF53187 10 203 1.09E-59 T 28-03-2018 CU254_RS20640 b842a98bcfda898a63bdc7b636b7ee94 417 SUPERFAMILY SSF53187 331 412 1.09E-59 T 28-03-2018 CU254_RS33975 c28d2981553352591b76dafa348f09c4 382 Gene3D G3DSA:3.50.50.60 4 340 4.1E-36 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS33975 c28d2981553352591b76dafa348f09c4 382 SUPERFAMILY SSF51905 263 369 1.3E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS33975 c28d2981553352591b76dafa348f09c4 382 SUPERFAMILY SSF51905 5 164 1.3E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS33975 c28d2981553352591b76dafa348f09c4 382 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 7.2E-11 T 28-03-2018 CU254_RS33975 c28d2981553352591b76dafa348f09c4 382 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 276 291 7.2E-11 T 28-03-2018 CU254_RS33975 c28d2981553352591b76dafa348f09c4 382 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 143 158 7.2E-11 T 28-03-2018 CU254_RS33975 c28d2981553352591b76dafa348f09c4 382 Pfam PF01494 FAD binding domain 5 319 4.2E-20 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CU254_RS07555 9f13e79a68e3836d404e700f6c57f41f 244 SUPERFAMILY SSF49482 18 239 4.32E-73 T 28-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 CU254_RS07555 9f13e79a68e3836d404e700f6c57f41f 244 Pfam PF12391 Protocatechuate 3,4-dioxygenase beta subunit N terminal 12 45 2.5E-14 T 28-03-2018 IPR024756 Protocatechuate 3,4-dioxygenase beta subunit, N-terminal KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3 CU254_RS07555 9f13e79a68e3836d404e700f6c57f41f 244 Pfam PF00775 Dioxygenase 51 230 2.7E-53 T 28-03-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 CU254_RS07555 9f13e79a68e3836d404e700f6c57f41f 244 TIGRFAM TIGR02423 protocat_alph: protocatechuate 3,4-dioxygenase, alpha subunit 73 237 2.1E-37 T 28-03-2018 IPR012786 Protocatechuate 3,4-dioxygenase, alpha subunit GO:0005506|GO:0018578|GO:0019439|GO:0055114 KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3 CU254_RS07555 9f13e79a68e3836d404e700f6c57f41f 244 Gene3D G3DSA:2.60.130.10 7 240 1.4E-65 T 28-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 CU254_RS07555 9f13e79a68e3836d404e700f6c57f41f 244 TIGRFAM TIGR02422 protocat_beta: protocatechuate 3,4-dioxygenase, beta subunit 20 239 9.2E-108 T 28-03-2018 IPR012785 Protocatechuate 3,4-dioxygenase, beta subunit GO:0005506|GO:0018578|GO:0019619|GO:0055114 KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3 CU254_RS07555 9f13e79a68e3836d404e700f6c57f41f 244 ProSitePatterns PS00083 Intradiol ring-cleavage dioxygenases signature. 82 110 - T 28-03-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 CU254_RS40695 4c41c4b04bcadc6b9eff3b2436e85ced 202 Gene3D G3DSA:3.40.50.2300 2 126 4.4E-34 T 28-03-2018 CU254_RS40695 4c41c4b04bcadc6b9eff3b2436e85ced 202 Gene3D G3DSA:1.10.10.10 127 202 7.4E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS40695 4c41c4b04bcadc6b9eff3b2436e85ced 202 Pfam PF00072 Response regulator receiver domain 5 117 5.7E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS40695 4c41c4b04bcadc6b9eff3b2436e85ced 202 Pfam PF00196 Bacterial regulatory proteins, luxR family 141 196 2.0E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS40695 4c41c4b04bcadc6b9eff3b2436e85ced 202 SUPERFAMILY SSF46894 131 202 1.39E-16 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS40695 4c41c4b04bcadc6b9eff3b2436e85ced 202 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 172 3.5E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS40695 4c41c4b04bcadc6b9eff3b2436e85ced 202 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 142 156 3.5E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS40695 4c41c4b04bcadc6b9eff3b2436e85ced 202 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 184 3.5E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS40695 4c41c4b04bcadc6b9eff3b2436e85ced 202 SUPERFAMILY SSF52172 2 130 1.85E-30 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS40695 4c41c4b04bcadc6b9eff3b2436e85ced 202 SMART SM00448 3 116 1.4E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS40695 4c41c4b04bcadc6b9eff3b2436e85ced 202 SMART SM00421 139 196 2.2E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS20900 686ee799b8f6f046dea4eb98d3bef4b6 665 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 36 444 1.1E-69 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CU254_RS20900 686ee799b8f6f046dea4eb98d3bef4b6 665 Gene3D G3DSA:1.20.1250.20 280 498 2.5E-28 T 28-03-2018 CU254_RS20900 686ee799b8f6f046dea4eb98d3bef4b6 665 Gene3D G3DSA:2.60.40.1120 582 656 4.4E-10 T 28-03-2018 CU254_RS20900 686ee799b8f6f046dea4eb98d3bef4b6 665 Pfam PF07690 Major Facilitator Superfamily 40 440 1.3E-57 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS20900 686ee799b8f6f046dea4eb98d3bef4b6 665 SUPERFAMILY SSF49478 584 646 7.06E-10 T 28-03-2018 CU254_RS20900 686ee799b8f6f046dea4eb98d3bef4b6 665 Gene3D G3DSA:2.60.40.1120 501 581 4.4E-4 T 28-03-2018 CU254_RS20900 686ee799b8f6f046dea4eb98d3bef4b6 665 SUPERFAMILY SSF103473 22 222 5.89E-75 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS20900 686ee799b8f6f046dea4eb98d3bef4b6 665 SUPERFAMILY SSF103473 276 492 5.89E-75 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS20900 686ee799b8f6f046dea4eb98d3bef4b6 665 Pfam PF13620 Carboxypeptidase regulatory-like domain 582 654 2.3E-11 T 28-03-2018 CU254_RS20900 686ee799b8f6f046dea4eb98d3bef4b6 665 Gene3D G3DSA:1.20.1250.20 30 227 1.2E-39 T 28-03-2018 CU254_RS20900 686ee799b8f6f046dea4eb98d3bef4b6 665 PRINTS PR01036 Tetracycline resistance protein TetB signature 38 62 1.4E-7 T 28-03-2018 CU254_RS20900 686ee799b8f6f046dea4eb98d3bef4b6 665 PRINTS PR01036 Tetracycline resistance protein TetB signature 357 377 1.4E-7 T 28-03-2018 CU254_RS20900 686ee799b8f6f046dea4eb98d3bef4b6 665 PRINTS PR01036 Tetracycline resistance protein TetB signature 159 183 1.4E-7 T 28-03-2018 CU254_RS27355 43180ca11b3914f695dd7aed007d3cc5 486 Pfam PF00171 Aldehyde dehydrogenase family 15 474 6.6E-142 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CU254_RS27355 43180ca11b3914f695dd7aed007d3cc5 486 Gene3D G3DSA:3.40.605.10 2 265 4.9E-83 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CU254_RS27355 43180ca11b3914f695dd7aed007d3cc5 486 SUPERFAMILY SSF53720 5 477 5.24E-141 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CU254_RS27355 43180ca11b3914f695dd7aed007d3cc5 486 Gene3D G3DSA:3.40.309.10 266 456 6.1E-61 T 28-03-2018 CU254_RS14260 fa487f92285f02e1538e1d915b6e81e5 726 SMART SM00028 592 625 320.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS14260 fa487f92285f02e1538e1d915b6e81e5 726 SMART SM00028 512 545 0.017 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS14260 fa487f92285f02e1538e1d915b6e81e5 726 SMART SM00028 632 665 16.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS14260 fa487f92285f02e1538e1d915b6e81e5 726 Gene3D G3DSA:1.10.260.40 4 86 2.1E-10 T 28-03-2018 CU254_RS14260 fa487f92285f02e1538e1d915b6e81e5 726 SUPERFAMILY SSF47413 4 61 4.79E-9 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS14260 fa487f92285f02e1538e1d915b6e81e5 726 Pfam PF13560 Helix-turn-helix domain 7 66 2.7E-12 T 28-03-2018 CU254_RS14260 fa487f92285f02e1538e1d915b6e81e5 726 Pfam PF00931 NB-ARC domain 109 338 4.5E-7 T 28-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 CU254_RS14260 fa487f92285f02e1538e1d915b6e81e5 726 SMART SM00530 10 65 3.4E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS14260 fa487f92285f02e1538e1d915b6e81e5 726 PRINTS PR00364 Disease resistance protein signature 270 284 8.3E-8 T 28-03-2018 CU254_RS14260 fa487f92285f02e1538e1d915b6e81e5 726 PRINTS PR00364 Disease resistance protein signature 190 204 8.3E-8 T 28-03-2018 CU254_RS14260 fa487f92285f02e1538e1d915b6e81e5 726 PRINTS PR00364 Disease resistance protein signature 113 128 8.3E-8 T 28-03-2018 CU254_RS14260 fa487f92285f02e1538e1d915b6e81e5 726 SUPERFAMILY SSF52540 80 335 1.8E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS14260 fa487f92285f02e1538e1d915b6e81e5 726 Gene3D G3DSA:1.25.40.10 601 716 7.0E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS14260 fa487f92285f02e1538e1d915b6e81e5 726 SUPERFAMILY SSF48452 500 671 6.83E-22 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS14260 fa487f92285f02e1538e1d915b6e81e5 726 Gene3D G3DSA:1.10.150.200 496 563 3.8E-12 T 28-03-2018 CU254_RS14260 fa487f92285f02e1538e1d915b6e81e5 726 Gene3D G3DSA:1.10.150.200 564 600 0.16 T 28-03-2018 CU254_RS14260 fa487f92285f02e1538e1d915b6e81e5 726 Pfam PF13424 Tetratricopeptide repeat 512 582 2.0E-8 T 28-03-2018 CU254_RS14260 fa487f92285f02e1538e1d915b6e81e5 726 Gene3D G3DSA:3.40.50.300 87 237 3.0E-18 T 28-03-2018 CU254_RS21155 bc952f8143f33349ba11e0fe5df97d75 396 Pfam PF00067 Cytochrome P450 270 366 1.9E-20 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS21155 bc952f8143f33349ba11e0fe5df97d75 396 PRINTS PR00359 B-class P450 signature 315 330 6.3E-53 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS21155 bc952f8143f33349ba11e0fe5df97d75 396 PRINTS PR00359 B-class P450 signature 187 209 6.3E-53 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS21155 bc952f8143f33349ba11e0fe5df97d75 396 PRINTS PR00359 B-class P450 signature 269 280 6.3E-53 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS21155 bc952f8143f33349ba11e0fe5df97d75 396 PRINTS PR00359 B-class P450 signature 287 314 6.3E-53 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS21155 bc952f8143f33349ba11e0fe5df97d75 396 PRINTS PR00359 B-class P450 signature 87 98 6.3E-53 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS21155 bc952f8143f33349ba11e0fe5df97d75 396 PRINTS PR00359 B-class P450 signature 345 356 6.3E-53 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS21155 bc952f8143f33349ba11e0fe5df97d75 396 PRINTS PR00359 B-class P450 signature 336 345 6.3E-53 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS21155 bc952f8143f33349ba11e0fe5df97d75 396 PRINTS PR00359 B-class P450 signature 134 150 6.3E-53 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS21155 bc952f8143f33349ba11e0fe5df97d75 396 PRINTS PR00359 B-class P450 signature 151 166 6.3E-53 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS21155 bc952f8143f33349ba11e0fe5df97d75 396 SUPERFAMILY SSF48264 9 396 8.12E-89 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS21155 bc952f8143f33349ba11e0fe5df97d75 396 Gene3D G3DSA:1.10.630.10 1 396 2.7E-78 T 28-03-2018 CU254_RS21155 bc952f8143f33349ba11e0fe5df97d75 396 PRINTS PR00385 P450 superfamily signature 269 280 3.6E-7 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS21155 bc952f8143f33349ba11e0fe5df97d75 396 PRINTS PR00385 P450 superfamily signature 345 356 3.6E-7 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS21155 bc952f8143f33349ba11e0fe5df97d75 396 PRINTS PR00385 P450 superfamily signature 336 345 3.6E-7 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS21155 bc952f8143f33349ba11e0fe5df97d75 396 PRINTS PR00385 P450 superfamily signature 233 250 3.6E-7 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS40495 04d1545ad616bbe57dd7a34deccf8b2d 73 Gene3D G3DSA:3.10.290.10 2 71 3.7E-16 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CU254_RS40495 04d1545ad616bbe57dd7a34deccf8b2d 73 SUPERFAMILY SSF55174 5 68 4.58E-18 T 28-03-2018 CU254_RS40495 04d1545ad616bbe57dd7a34deccf8b2d 73 Pfam PF13275 S4 domain 6 69 3.6E-25 T 28-03-2018 CU254_RS37360 98429dd13263fbabf355ddd0a08179bb 195 Gene3D G3DSA:2.60.40.200 61 194 2.1E-11 T 28-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CU254_RS37360 98429dd13263fbabf355ddd0a08179bb 195 Pfam PF00080 Copper/zinc superoxide dismutase (SODC) 79 190 2.6E-5 T 28-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CU254_RS37360 98429dd13263fbabf355ddd0a08179bb 195 SUPERFAMILY SSF49329 78 190 6.02E-10 T 28-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CU254_RS09680 ed3c9be0726d6eadcec94e93f6839b72 222 Gene3D G3DSA:1.10.10.10 118 221 1.7E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS09680 ed3c9be0726d6eadcec94e93f6839b72 222 SMART SM00862 145 217 3.2E-23 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS09680 ed3c9be0726d6eadcec94e93f6839b72 222 Pfam PF00072 Response regulator receiver domain 3 110 7.6E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS09680 ed3c9be0726d6eadcec94e93f6839b72 222 SUPERFAMILY SSF52172 2 179 6.7E-31 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS09680 ed3c9be0726d6eadcec94e93f6839b72 222 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 217 2.1E-23 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS09680 ed3c9be0726d6eadcec94e93f6839b72 222 SMART SM00448 1 109 3.1E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS09680 ed3c9be0726d6eadcec94e93f6839b72 222 Gene3D G3DSA:3.40.50.2300 1 117 2.1E-26 T 28-03-2018 CU254_RS00995 a45eccce6e12452390383fde536635fb 351 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 214 347 6.7E-37 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CU254_RS00995 a45eccce6e12452390383fde536635fb 351 Gene3D G3DSA:3.30.465.10 75 225 5.0E-48 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CU254_RS00995 a45eccce6e12452390383fde536635fb 351 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 12 347 3.5E-48 T 28-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CU254_RS00995 a45eccce6e12452390383fde536635fb 351 SUPERFAMILY SSF56194 212 349 1.19E-29 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CU254_RS00995 a45eccce6e12452390383fde536635fb 351 Gene3D G3DSA:3.30.43.10 10 74 8.4E-21 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CU254_RS00995 a45eccce6e12452390383fde536635fb 351 Gene3D G3DSA:3.90.78.10 230 347 1.0E-38 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CU254_RS00995 a45eccce6e12452390383fde536635fb 351 Pfam PF01565 FAD binding domain 28 152 9.5E-23 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CU254_RS00995 a45eccce6e12452390383fde536635fb 351 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 351 74.602 T 28-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CU254_RS00995 a45eccce6e12452390383fde536635fb 351 SUPERFAMILY SSF56176 12 187 1.23E-38 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CU254_RS33400 7c546a429415c8711c276156d8c58eaf 380 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 65 74 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CU254_RS33400 7c546a429415c8711c276156d8c58eaf 380 SUPERFAMILY SSF55031 166 257 3.4E-19 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CU254_RS33400 7c546a429415c8711c276156d8c58eaf 380 Pfam PF07687 Peptidase dimerisation domain 164 256 2.9E-13 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CU254_RS33400 7c546a429415c8711c276156d8c58eaf 380 Gene3D G3DSA:3.40.630.10 1 363 2.7E-46 T 28-03-2018 CU254_RS33400 7c546a429415c8711c276156d8c58eaf 380 SUPERFAMILY SSF53187 2 175 5.47E-44 T 28-03-2018 CU254_RS33400 7c546a429415c8711c276156d8c58eaf 380 SUPERFAMILY SSF53187 284 359 5.47E-44 T 28-03-2018 CU254_RS33400 7c546a429415c8711c276156d8c58eaf 380 Pfam PF01546 Peptidase family M20/M25/M40 66 358 5.0E-26 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CU254_RS33400 7c546a429415c8711c276156d8c58eaf 380 PIRSF PIRSF037238 1 360 1.5E-131 T 28-03-2018 IPR017150 Peptidase M20, glutamate carboxypeptidase CU254_RS37680 ec34b9ef2dd35259206a4b3c3241421b 79 Gene3D G3DSA:3.30.1280.10 3 76 5.4E-27 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CU254_RS37680 ec34b9ef2dd35259206a4b3c3241421b 79 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 4 74 9.5E-16 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CU254_RS37680 ec34b9ef2dd35259206a4b3c3241421b 79 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 2 76 20.022 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CU254_RS37680 ec34b9ef2dd35259206a4b3c3241421b 79 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 11 75 5.0E-16 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CU254_RS37680 ec34b9ef2dd35259206a4b3c3241421b 79 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 4 75 2.1E-25 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CU254_RS37680 ec34b9ef2dd35259206a4b3c3241421b 79 SUPERFAMILY SSF82697 3 75 1.71E-22 T 28-03-2018 CU254_RS14555 3acf939ea1194f3877da09561f1fa4a7 1088 Gene3D G3DSA:2.70.98.10 34 334 9.3E-102 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 CU254_RS14555 3acf939ea1194f3877da09561f1fa4a7 1088 SUPERFAMILY SSF48208 279 750 1.04E-19 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CU254_RS14555 3acf939ea1194f3877da09561f1fa4a7 1088 Gene3D G3DSA:1.20.1050.60 357 453 2.2E-23 T 28-03-2018 CU254_RS14555 3acf939ea1194f3877da09561f1fa4a7 1088 Pfam PF10633 NPCBM-associated, NEW3 domain of alpha-galactosidase 813 883 1.6E-5 T 28-03-2018 IPR018905 Alpha-galactosidase, NEW3 domain CU254_RS14555 3acf939ea1194f3877da09561f1fa4a7 1088 Gene3D G3DSA:3.30.2080.10 629 778 6.4E-52 T 28-03-2018 CU254_RS14555 3acf939ea1194f3877da09561f1fa4a7 1088 TIGRFAM TIGR01180 aman2_put: putative alpha-1,2-mannosidase 13 769 6.9E-169 T 28-03-2018 IPR005887 Alpha-1,2-mannosidase, putative CU254_RS14555 3acf939ea1194f3877da09561f1fa4a7 1088 Gene3D G3DSA:1.20.1610.10 454 628 4.4E-49 T 28-03-2018 CU254_RS14555 3acf939ea1194f3877da09561f1fa4a7 1088 Pfam PF07971 Glycosyl hydrolase family 92 248 766 2.8E-153 T 28-03-2018 IPR012939 Glycosyl hydrolase family 92 CU254_RS10465 c457a9a6faab6d5b9cef5826ad44a0b9 299 Gene3D G3DSA:3.10.180.10 1 132 3.1E-11 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS10465 c457a9a6faab6d5b9cef5826ad44a0b9 299 SUPERFAMILY SSF54593 135 292 1.15E-34 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS10465 c457a9a6faab6d5b9cef5826ad44a0b9 299 SUPERFAMILY SSF54593 1 123 3.44E-22 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS10465 c457a9a6faab6d5b9cef5826ad44a0b9 299 Gene3D G3DSA:3.10.180.10 133 298 4.0E-31 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS10465 c457a9a6faab6d5b9cef5826ad44a0b9 299 ProSitePatterns PS00082 Extradiol ring-cleavage dioxygenases signature. 245 266 - T 28-03-2018 IPR000486 Extradiol ring-cleavage dioxygenase, class I /II GO:0003824|GO:0006725|GO:0008198|GO:0055114 CU254_RS10465 c457a9a6faab6d5b9cef5826ad44a0b9 299 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 142 267 2.2E-22 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CU254_RS03725 06d6f870ce4a2d7395c9c62bc0978e1a 264 Gene3D G3DSA:1.10.12.10 222 264 4.5E-14 T 28-03-2018 IPR014748 Crontonase, C-terminal CU254_RS03725 06d6f870ce4a2d7395c9c62bc0978e1a 264 Gene3D G3DSA:3.90.226.10 5 221 3.7E-63 T 28-03-2018 CU254_RS03725 06d6f870ce4a2d7395c9c62bc0978e1a 264 SUPERFAMILY SSF52096 4 263 5.15E-82 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS03725 06d6f870ce4a2d7395c9c62bc0978e1a 264 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 263 6.8E-62 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CU254_RS30420 941ba34b2b69bd6b2d95fd1dc1413da4 313 SUPERFAMILY SSF51735 10 309 2.15E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS30420 941ba34b2b69bd6b2d95fd1dc1413da4 313 Gene3D G3DSA:3.40.50.720 4 106 4.4E-11 T 28-03-2018 CU254_RS30420 941ba34b2b69bd6b2d95fd1dc1413da4 313 Gene3D G3DSA:3.90.25.10 154 312 1.3E-19 T 28-03-2018 CU254_RS30420 941ba34b2b69bd6b2d95fd1dc1413da4 313 Pfam PF01370 NAD dependent epimerase/dehydratase family 10 208 7.8E-14 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CU254_RS32905 65d9362f2751682235d3a13dfc45c3a3 515 Gene3D G3DSA:2.160.20.10 80 473 1.5E-18 T 28-03-2018 IPR012334 Pectin lyase fold CU254_RS32905 65d9362f2751682235d3a13dfc45c3a3 515 SUPERFAMILY SSF51126 274 464 8.05E-13 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor CU254_RS32905 65d9362f2751682235d3a13dfc45c3a3 515 SUPERFAMILY SSF51126 86 153 8.05E-13 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor CU254_RS32905 65d9362f2751682235d3a13dfc45c3a3 515 SUPERFAMILY SSF51126 201 215 8.05E-13 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor CU254_RS21025 5510507b157c254f9e736879aa7c75a9 240 SUPERFAMILY SSF52833 4 176 7.16E-13 T 28-03-2018 IPR012336 Thioredoxin-like fold CU254_RS21025 5510507b157c254f9e736879aa7c75a9 240 Gene3D G3DSA:3.40.30.10 2 43 5.5E-7 T 28-03-2018 CU254_RS21025 5510507b157c254f9e736879aa7c75a9 240 Gene3D G3DSA:3.40.30.10 44 177 7.2E-9 T 28-03-2018 CU254_RS38950 d131ec847afca9760d3111df870b6432 82 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 3 80 20.29 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS38950 d131ec847afca9760d3111df870b6432 82 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 28 79 1.0E-21 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS38950 d131ec847afca9760d3111df870b6432 82 SUPERFAMILY SSF46911 6 79 5.36E-25 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS38950 d131ec847afca9760d3111df870b6432 82 Gene3D G3DSA:4.10.640.10 2 82 1.1E-29 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS38950 d131ec847afca9760d3111df870b6432 82 PRINTS PR00974 Ribosomal protein S18 family signature 35 45 5.2E-16 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS38950 d131ec847afca9760d3111df870b6432 82 PRINTS PR00974 Ribosomal protein S18 family signature 67 77 5.2E-16 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS38950 d131ec847afca9760d3111df870b6432 82 PRINTS PR00974 Ribosomal protein S18 family signature 53 67 5.2E-16 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS38950 d131ec847afca9760d3111df870b6432 82 PRINTS PR00974 Ribosomal protein S18 family signature 45 52 5.2E-16 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS38950 d131ec847afca9760d3111df870b6432 82 TIGRFAM TIGR00165 S18: ribosomal protein bS18 9 79 4.4E-27 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS38950 d131ec847afca9760d3111df870b6432 82 ProSitePatterns PS00057 Ribosomal protein S18 signature. 28 51 - T 28-03-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS38950 d131ec847afca9760d3111df870b6432 82 Pfam PF01084 Ribosomal protein S18 26 75 2.4E-23 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS29670 d225bf3c10fafeb8507d9006035152e2 536 SUPERFAMILY SSF51338 4 54 2.05E-21 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS29670 d225bf3c10fafeb8507d9006035152e2 536 SUPERFAMILY SSF51338 492 534 2.05E-21 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS29670 d225bf3c10fafeb8507d9006035152e2 536 Pfam PF07969 Amidohydrolase family 42 533 1.3E-95 T 28-03-2018 IPR013108 Amidohydrolase 3 CU254_RS29670 d225bf3c10fafeb8507d9006035152e2 536 Gene3D G3DSA:3.20.20.140 180 476 3.3E-53 T 28-03-2018 CU254_RS29670 d225bf3c10fafeb8507d9006035152e2 536 Gene3D G3DSA:2.30.40.10 2 108 1.3E-17 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS29670 d225bf3c10fafeb8507d9006035152e2 536 Gene3D G3DSA:2.30.40.10 477 536 2.1E-15 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS29670 d225bf3c10fafeb8507d9006035152e2 536 SUPERFAMILY SSF51556 53 105 1.4E-38 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS29670 d225bf3c10fafeb8507d9006035152e2 536 SUPERFAMILY SSF51556 191 493 1.4E-38 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS04190 fec654d0a0763bd545a7fd08cb680c2e 329 SUPERFAMILY SSF161098 72 314 3.14E-50 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS04190 fec654d0a0763bd545a7fd08cb680c2e 329 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 315 4.6E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS04190 fec654d0a0763bd545a7fd08cb680c2e 329 Gene3D G3DSA:1.10.3720.10 30 328 1.5E-48 T 28-03-2018 CU254_RS04190 fec654d0a0763bd545a7fd08cb680c2e 329 SUPERFAMILY SSF160964 27 66 2.75E-5 T 28-03-2018 CU254_RS31515 14557f304eb09910d100a45b91d531b0 147 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 6 142 2.0E-7 T 28-03-2018 IPR028973 PhnB-like CU254_RS31515 14557f304eb09910d100a45b91d531b0 147 Gene3D G3DSA:3.10.180.10 1 146 4.8E-22 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS31515 14557f304eb09910d100a45b91d531b0 147 SUPERFAMILY SSF54593 4 144 5.46E-23 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS20740 3e8ad45d58c5fece7ff24919d2836b1d 609 Gene3D G3DSA:2.40.30.10 220 310 3.1E-17 T 28-03-2018 CU254_RS20740 3e8ad45d58c5fece7ff24919d2836b1d 609 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 8 414 3.4E-168 T 28-03-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 CU254_RS20740 3e8ad45d58c5fece7ff24919d2836b1d 609 SUPERFAMILY SSF52540 437 608 1.1E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS20740 3e8ad45d58c5fece7ff24919d2836b1d 609 PRINTS PR00315 GTP-binding elongation factor signature 103 114 2.4E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CU254_RS20740 3e8ad45d58c5fece7ff24919d2836b1d 609 PRINTS PR00315 GTP-binding elongation factor signature 8 21 2.4E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CU254_RS20740 3e8ad45d58c5fece7ff24919d2836b1d 609 PRINTS PR00315 GTP-binding elongation factor signature 140 149 2.4E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CU254_RS20740 3e8ad45d58c5fece7ff24919d2836b1d 609 PRINTS PR00315 GTP-binding elongation factor signature 87 97 2.4E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CU254_RS20740 3e8ad45d58c5fece7ff24919d2836b1d 609 PRINTS PR00315 GTP-binding elongation factor signature 67 75 2.4E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CU254_RS20740 3e8ad45d58c5fece7ff24919d2836b1d 609 Pfam PF01583 Adenylylsulphate kinase 439 592 2.5E-68 T 28-03-2018 CU254_RS20740 3e8ad45d58c5fece7ff24919d2836b1d 609 SUPERFAMILY SSF52540 7 206 1.46E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS20740 3e8ad45d58c5fece7ff24919d2836b1d 609 Gene3D G3DSA:2.40.30.10 311 416 4.7E-25 T 28-03-2018 CU254_RS20740 3e8ad45d58c5fece7ff24919d2836b1d 609 SUPERFAMILY SSF50447 222 308 2.65E-17 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CU254_RS20740 3e8ad45d58c5fece7ff24919d2836b1d 609 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 60 75 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site CU254_RS20740 3e8ad45d58c5fece7ff24919d2836b1d 609 Gene3D G3DSA:3.40.50.300 435 609 2.8E-42 T 28-03-2018 CU254_RS20740 3e8ad45d58c5fece7ff24919d2836b1d 609 Pfam PF00009 Elongation factor Tu GTP binding domain 7 190 4.2E-43 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CU254_RS20740 3e8ad45d58c5fece7ff24919d2836b1d 609 Gene3D G3DSA:3.40.50.300 4 214 3.2E-40 T 28-03-2018 CU254_RS20740 3e8ad45d58c5fece7ff24919d2836b1d 609 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 426 602 1.5E-65 T 28-03-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 CU254_RS20740 3e8ad45d58c5fece7ff24919d2836b1d 609 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 438 609 34.349 T 28-03-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 CU254_RS20740 3e8ad45d58c5fece7ff24919d2836b1d 609 SUPERFAMILY SSF50465 311 415 1.34E-29 T 28-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal CU254_RS02880 6eb73c929ff700a2a3e4d320983a7370 834 SMART SM00490 277 363 9.1E-14 T 28-03-2018 IPR001650 Helicase, C-terminal CU254_RS02880 6eb73c929ff700a2a3e4d320983a7370 834 Gene3D G3DSA:3.40.50.300 19 201 6.3E-27 T 28-03-2018 CU254_RS02880 6eb73c929ff700a2a3e4d320983a7370 834 Pfam PF00270 DEAD/DEAH box helicase 33 178 8.9E-10 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CU254_RS02880 6eb73c929ff700a2a3e4d320983a7370 834 Pfam PF00271 Helicase conserved C-terminal domain 284 363 2.8E-6 T 28-03-2018 IPR001650 Helicase, C-terminal CU254_RS02880 6eb73c929ff700a2a3e4d320983a7370 834 Gene3D G3DSA:3.40.50.300 212 406 1.0E-19 T 28-03-2018 CU254_RS02880 6eb73c929ff700a2a3e4d320983a7370 834 SUPERFAMILY SSF52540 44 250 1.75E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS02880 6eb73c929ff700a2a3e4d320983a7370 834 SUPERFAMILY SSF52540 283 375 1.75E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS02880 6eb73c929ff700a2a3e4d320983a7370 834 SMART SM00487 27 210 8.3E-16 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CU254_RS02880 6eb73c929ff700a2a3e4d320983a7370 834 Pfam PF12029 Domain of unknown function (DUF3516) 374 831 4.7E-218 T 28-03-2018 IPR021904 Protein of unknown function DUF3516 CU254_RS40800 33c25b7a35eb29679867a88080dad1ce 280 SUPERFAMILY SSF51735 3 270 4.34E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS40800 33c25b7a35eb29679867a88080dad1ce 280 Gene3D G3DSA:3.40.50.720 1 276 3.3E-25 T 28-03-2018 CU254_RS40800 33c25b7a35eb29679867a88080dad1ce 280 Pfam PF13460 NAD(P)H-binding 6 178 3.2E-20 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS26925 401b9059fc6e40673a23ad1b11b95482 291 Gene3D G3DSA:3.40.50.1110 27 291 1.6E-36 T 28-03-2018 CU254_RS26925 401b9059fc6e40673a23ad1b11b95482 291 SUPERFAMILY SSF52266 32 290 1.67E-54 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CU254_RS26925 401b9059fc6e40673a23ad1b11b95482 291 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 36 277 5.1E-22 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CU254_RS09650 a5ca603b040363eaf167dbe397e50967 250 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 18 219 1.7E-42 T 28-03-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CU254_RS09650 a5ca603b040363eaf167dbe397e50967 250 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 7 105 1.5E-26 T 28-03-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CU254_RS09650 a5ca603b040363eaf167dbe397e50967 250 Pfam PF13183 4Fe-4S dicluster domain 140 216 7.1E-13 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CU254_RS09650 a5ca603b040363eaf167dbe397e50967 250 SUPERFAMILY SSF46548 122 228 1.92E-18 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CU254_RS09650 a5ca603b040363eaf167dbe397e50967 250 SUPERFAMILY SSF54292 3 103 1.44E-23 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CU254_RS09650 a5ca603b040363eaf167dbe397e50967 250 Gene3D G3DSA:1.10.1060.10 103 237 3.2E-11 T 28-03-2018 CU254_RS09650 a5ca603b040363eaf167dbe397e50967 250 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 53 61 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CU254_RS09650 a5ca603b040363eaf167dbe397e50967 250 Gene3D G3DSA:3.10.20.30 1 102 4.1E-28 T 28-03-2018 IPR012675 Beta-grasp domain CU254_RS23600 8ab9d08ae9c67eca9c60d308f31a45ce 584 SUPERFAMILY SSF50447 169 260 2.29E-18 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CU254_RS23600 8ab9d08ae9c67eca9c60d308f31a45ce 584 Pfam PF00009 Elongation factor Tu GTP binding domain 2 160 5.0E-22 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CU254_RS23600 8ab9d08ae9c67eca9c60d308f31a45ce 584 Gene3D G3DSA:1.10.10.10 519 573 2.3E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS23600 8ab9d08ae9c67eca9c60d308f31a45ce 584 Gene3D G3DSA:2.40.30.10 169 275 4.6E-22 T 28-03-2018 CU254_RS23600 8ab9d08ae9c67eca9c60d308f31a45ce 584 Gene3D G3DSA:3.40.50.300 1 165 4.3E-26 T 28-03-2018 CU254_RS23600 8ab9d08ae9c67eca9c60d308f31a45ce 584 SUPERFAMILY SSF52540 2 189 7.9E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS23600 8ab9d08ae9c67eca9c60d308f31a45ce 584 TIGRFAM TIGR00475 selB: selenocysteine-specific translation elongation factor 3 338 8.2E-78 T 28-03-2018 IPR004535 Translation elongation factor, selenocysteine-specific GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 CU254_RS23600 8ab9d08ae9c67eca9c60d308f31a45ce 584 Pfam PF09107 Elongation factor SelB, winged helix 528 570 4.2E-10 T 28-03-2018 IPR015191 Translation elongation factor SelB, winged helix, type 3 GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 CU254_RS23600 8ab9d08ae9c67eca9c60d308f31a45ce 584 Gene3D G3DSA:1.10.10.10 398 474 4.0E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS15975 5c552c42346148a87cdf253d44b4beeb 331 Gene3D G3DSA:3.20.20.140 6 331 7.0E-57 T 28-03-2018 CU254_RS15975 5c552c42346148a87cdf253d44b4beeb 331 SUPERFAMILY SSF51556 1 330 1.18E-73 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS15975 5c552c42346148a87cdf253d44b4beeb 331 Pfam PF04909 Amidohydrolase 55 330 1.9E-40 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CU254_RS02335 50e045682778b5153b5a476206ce70de 348 Gene3D G3DSA:3.30.420.40 150 300 4.3E-20 T 28-03-2018 CU254_RS02335 50e045682778b5153b5a476206ce70de 348 Gene3D G3DSA:3.30.420.40 3 149 4.4E-36 T 28-03-2018 CU254_RS02335 50e045682778b5153b5a476206ce70de 348 ProSitePatterns PS01016 Glycoprotease family signature. 102 122 - T 28-03-2018 IPR017860 Peptidase M22, conserved site KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618|Reactome: R-HSA-6782315 CU254_RS02335 50e045682778b5153b5a476206ce70de 348 SUPERFAMILY SSF53067 5 319 8.2E-37 T 28-03-2018 CU254_RS02335 50e045682778b5153b5a476206ce70de 348 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 82 102 1.0E-50 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CU254_RS02335 50e045682778b5153b5a476206ce70de 348 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 103 122 1.0E-50 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CU254_RS02335 50e045682778b5153b5a476206ce70de 348 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 161 182 1.0E-50 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CU254_RS02335 50e045682778b5153b5a476206ce70de 348 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 6 19 1.0E-50 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CU254_RS02335 50e045682778b5153b5a476206ce70de 348 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 274 283 1.0E-50 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CU254_RS02335 50e045682778b5153b5a476206ce70de 348 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 137 149 1.0E-50 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CU254_RS02335 50e045682778b5153b5a476206ce70de 348 Pfam PF00814 Glycoprotease family 29 317 1.5E-97 T 28-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CU254_RS02335 50e045682778b5153b5a476206ce70de 348 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 3 343 61.238 T 28-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CU254_RS02335 50e045682778b5153b5a476206ce70de 348 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 5 323 6.3E-127 T 28-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CU254_RS02335 50e045682778b5153b5a476206ce70de 348 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 6 317 1.4E-97 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CU254_RS13060 c9cfd09e141f3d425a1f53287da2d657 215 Pfam PF06197 Protein of unknown function (DUF998) 23 209 1.7E-19 T 28-03-2018 IPR009339 Protein of unknown function DUF998 CU254_RS35435 73292f4ff34bc418581ae614ca8b46e9 322 Pfam PF01066 CDP-alcohol phosphatidyltransferase 12 75 9.2E-13 T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CU254_RS35435 73292f4ff34bc418581ae614ca8b46e9 322 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 17 181 4.3E-33 T 28-03-2018 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 CU254_RS35435 73292f4ff34bc418581ae614ca8b46e9 322 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 53 75 - T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CU254_RS00755 5d8b4dc996b0e0244ea1d180f386e07b 397 SUPERFAMILY SSF103473 8 392 1.57E-46 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS00755 5d8b4dc996b0e0244ea1d180f386e07b 397 Gene3D G3DSA:1.20.1250.20 3 197 1.6E-22 T 28-03-2018 CU254_RS00755 5d8b4dc996b0e0244ea1d180f386e07b 397 Pfam PF07690 Major Facilitator Superfamily 19 312 1.5E-31 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS00755 5d8b4dc996b0e0244ea1d180f386e07b 397 Gene3D G3DSA:1.20.1250.20 200 395 2.9E-15 T 28-03-2018 CU254_RS31190 27713841e5b27b9716d5e1297e958c3d 673 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 539 668 1.2E-38 T 28-03-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CU254_RS31190 27713841e5b27b9716d5e1297e958c3d 673 Pfam PF02310 B12 binding domain 541 644 8.4E-15 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CU254_RS31190 27713841e5b27b9716d5e1297e958c3d 673 Gene3D G3DSA:3.20.20.240 2 503 1.8E-165 T 28-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CU254_RS31190 27713841e5b27b9716d5e1297e958c3d 673 Gene3D G3DSA:3.40.50.280 522 670 4.8E-35 T 28-03-2018 CU254_RS31190 27713841e5b27b9716d5e1297e958c3d 673 SUPERFAMILY SSF51703 7 503 2.62E-157 T 28-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CU254_RS31190 27713841e5b27b9716d5e1297e958c3d 673 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 3 507 3.5E-137 T 28-03-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CU254_RS31190 27713841e5b27b9716d5e1297e958c3d 673 SUPERFAMILY SSF52242 517 666 9.29E-48 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CU254_RS31190 27713841e5b27b9716d5e1297e958c3d 673 Pfam PF01642 Methylmalonyl-CoA mutase 7 501 1.8E-130 T 28-03-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CU254_RS00830 9aebde09d9c07062d48324580ed90a11 69 SUPERFAMILY SSF88659 39 65 8.5E-5 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS00830 9aebde09d9c07062d48324580ed90a11 69 Gene3D G3DSA:1.10.10.10 22 68 1.7E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS23035 52cc95dfd1ad4dcbafacf7d60509b4e8 159 Gene3D G3DSA:2.30.110.10 20 155 7.2E-35 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS23035 52cc95dfd1ad4dcbafacf7d60509b4e8 159 SUPERFAMILY SSF50475 48 149 7.86E-8 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS23035 52cc95dfd1ad4dcbafacf7d60509b4e8 159 Pfam PF04075 F420H(2)-dependent quinone reductase 34 153 4.5E-26 T 28-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CU254_RS23035 52cc95dfd1ad4dcbafacf7d60509b4e8 159 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 42 153 3.0E-28 T 28-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CU254_RS08665 d447f9d3cf8aa221536a6f069bb21a95 489 SUPERFAMILY SSF103473 6 195 1.4E-63 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS08665 d447f9d3cf8aa221536a6f069bb21a95 489 SUPERFAMILY SSF103473 256 470 1.4E-63 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS08665 d447f9d3cf8aa221536a6f069bb21a95 489 Gene3D G3DSA:1.20.1250.20 267 481 6.9E-25 T 28-03-2018 CU254_RS08665 d447f9d3cf8aa221536a6f069bb21a95 489 PRINTS PR01036 Tetracycline resistance protein TetB signature 16 40 6.3E-6 T 28-03-2018 CU254_RS08665 d447f9d3cf8aa221536a6f069bb21a95 489 PRINTS PR01036 Tetracycline resistance protein TetB signature 137 161 6.3E-6 T 28-03-2018 CU254_RS08665 d447f9d3cf8aa221536a6f069bb21a95 489 Pfam PF07690 Major Facilitator Superfamily 18 421 3.1E-47 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS08665 d447f9d3cf8aa221536a6f069bb21a95 489 Gene3D G3DSA:1.20.1250.20 7 206 3.4E-36 T 28-03-2018 CU254_RS07080 cb6631b6f2420b00a369bdbbcec12d92 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 227 1.4E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS07080 cb6631b6f2420b00a369bdbbcec12d92 233 SMART SM00448 7 118 1.9E-38 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS07080 cb6631b6f2420b00a369bdbbcec12d92 233 Pfam PF00072 Response regulator receiver domain 10 118 9.5E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS07080 cb6631b6f2420b00a369bdbbcec12d92 233 SUPERFAMILY SSF52172 5 179 4.23E-38 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS07080 cb6631b6f2420b00a369bdbbcec12d92 233 SMART SM00862 154 228 2.4E-26 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS07080 cb6631b6f2420b00a369bdbbcec12d92 233 Gene3D G3DSA:1.10.10.10 131 232 1.3E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS07080 cb6631b6f2420b00a369bdbbcec12d92 233 Gene3D G3DSA:3.40.50.2300 1 130 9.1E-35 T 28-03-2018 CU254_RS27040 9c75431753a95bbbdffc56b1599f9f98 460 Hamap MF_00303 Trigger factor [tig]. 1 424 19.069 T 28-03-2018 IPR005215 Trigger factor GO:0015031 CU254_RS27040 9c75431753a95bbbdffc56b1599f9f98 460 SUPERFAMILY SSF54534 134 244 1.73E-21 T 28-03-2018 CU254_RS27040 9c75431753a95bbbdffc56b1599f9f98 460 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 258 417 1.9E-32 T 28-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 CU254_RS27040 9c75431753a95bbbdffc56b1599f9f98 460 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 158 215 2.9E-5 T 28-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain CU254_RS27040 9c75431753a95bbbdffc56b1599f9f98 460 SUPERFAMILY SSF109998 246 434 1.47E-37 T 28-03-2018 IPR027304 Trigger factor/SurA domain CU254_RS27040 9c75431753a95bbbdffc56b1599f9f98 460 SUPERFAMILY SSF102735 1 131 8.37E-35 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CU254_RS27040 9c75431753a95bbbdffc56b1599f9f98 460 Gene3D G3DSA:3.30.70.1050 1 119 1.9E-34 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CU254_RS27040 9c75431753a95bbbdffc56b1599f9f98 460 Gene3D G3DSA:3.10.50.40 129 225 9.8E-8 T 28-03-2018 CU254_RS27040 9c75431753a95bbbdffc56b1599f9f98 460 Pfam PF05697 Bacterial trigger factor protein (TF) 2 145 1.2E-39 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CU254_RS27040 9c75431753a95bbbdffc56b1599f9f98 460 TIGRFAM TIGR00115 tig: trigger factor 12 416 5.0E-116 T 28-03-2018 IPR005215 Trigger factor GO:0015031 CU254_RS27040 9c75431753a95bbbdffc56b1599f9f98 460 PIRSF PIRSF003095 1 444 7.5E-114 T 28-03-2018 IPR005215 Trigger factor GO:0015031 CU254_RS27040 9c75431753a95bbbdffc56b1599f9f98 460 Gene3D G3DSA:1.10.3120.10 226 395 2.2E-41 T 28-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 CU254_RS27060 6c55111166ce682447bad5b65f18e2db 421 SUPERFAMILY SSF53448 23 237 3.05E-37 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS27060 6c55111166ce682447bad5b65f18e2db 421 Pfam PF00535 Glycosyl transferase family 2 29 194 2.9E-24 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CU254_RS27060 6c55111166ce682447bad5b65f18e2db 421 Pfam PF04138 GtrA-like protein 293 410 1.7E-10 T 28-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 CU254_RS27060 6c55111166ce682447bad5b65f18e2db 421 Gene3D G3DSA:3.90.550.10 1 268 1.0E-34 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS25075 7ea83ec7404ad27a264f14d90968d6dc 266 SUPERFAMILY SSF55781 83 262 2.42E-35 T 28-03-2018 IPR029016 GAF domain-like CU254_RS25075 7ea83ec7404ad27a264f14d90968d6dc 266 Pfam PF09339 IclR helix-turn-helix domain 21 70 3.3E-14 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS25075 7ea83ec7404ad27a264f14d90968d6dc 266 Gene3D G3DSA:1.10.10.10 9 79 3.7E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS25075 7ea83ec7404ad27a264f14d90968d6dc 266 Gene3D G3DSA:3.30.450.40 84 266 6.4E-34 T 28-03-2018 IPR029016 GAF domain-like CU254_RS25075 7ea83ec7404ad27a264f14d90968d6dc 266 Pfam PF01614 Bacterial transcriptional regulator 142 259 1.1E-11 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal CU254_RS25075 7ea83ec7404ad27a264f14d90968d6dc 266 SMART SM00346 18 108 2.1E-15 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS25075 7ea83ec7404ad27a264f14d90968d6dc 266 SUPERFAMILY SSF46785 21 90 1.34E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS38135 f56d13e21fbaf8098d5f100515f93b1a 136 SUPERFAMILY SSF54593 3 135 8.59E-32 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS38135 f56d13e21fbaf8098d5f100515f93b1a 136 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 131 1.7E-20 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CU254_RS38135 f56d13e21fbaf8098d5f100515f93b1a 136 Gene3D G3DSA:3.10.180.10 1 136 2.7E-29 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS28415 9b75b7e36569de19c6e0ac6175d9b5a4 291 SUPERFAMILY SSF53850 92 287 9.64E-18 T 28-03-2018 CU254_RS28415 9b75b7e36569de19c6e0ac6175d9b5a4 291 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 2.4E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS28415 9b75b7e36569de19c6e0ac6175d9b5a4 291 SUPERFAMILY SSF46785 2 84 1.29E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS28415 9b75b7e36569de19c6e0ac6175d9b5a4 291 Gene3D G3DSA:3.40.190.10 173 258 8.1E-10 T 28-03-2018 CU254_RS28415 9b75b7e36569de19c6e0ac6175d9b5a4 291 Gene3D G3DSA:1.10.10.10 1 83 1.8E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS28415 9b75b7e36569de19c6e0ac6175d9b5a4 291 Gene3D G3DSA:3.40.190.10 88 172 3.7E-6 T 28-03-2018 CU254_RS28415 9b75b7e36569de19c6e0ac6175d9b5a4 291 Pfam PF03466 LysR substrate binding domain 92 284 6.4E-15 T 28-03-2018 IPR005119 LysR, substrate-binding CU254_RS28415 9b75b7e36569de19c6e0ac6175d9b5a4 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.7E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS28415 9b75b7e36569de19c6e0ac6175d9b5a4 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.7E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS28415 9b75b7e36569de19c6e0ac6175d9b5a4 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.7E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS21105 7d804beea1bdf5825327a0b71085a1af 289 Gene3D G3DSA:3.60.15.10 1 289 1.1E-31 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS21105 7d804beea1bdf5825327a0b71085a1af 289 SUPERFAMILY SSF56281 1 289 2.9E-32 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS21105 7d804beea1bdf5825327a0b71085a1af 289 Pfam PF12706 Beta-lactamase superfamily domain 44 246 1.7E-25 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS21105 7d804beea1bdf5825327a0b71085a1af 289 Hamap MF_00653 Coenzyme PQQ synthesis protein B [pqqB]. 1 289 79.712 T 28-03-2018 IPR011842 Coenzyme PQQ biosynthesis protein B GO:0006810|GO:0018189 CU254_RS31695 a50d032e2112528ddba09e43d3dcc861 500 Pfam PF00171 Aldehyde dehydrogenase family 25 480 2.6E-145 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CU254_RS31695 a50d032e2112528ddba09e43d3dcc861 500 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 278 289 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CU254_RS31695 a50d032e2112528ddba09e43d3dcc861 500 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 10 484 4.1E-207 T 28-03-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373|Reactome: R-HSA-70895 CU254_RS31695 a50d032e2112528ddba09e43d3dcc861 500 Gene3D G3DSA:3.40.309.10 267 463 2.1E-66 T 28-03-2018 CU254_RS31695 a50d032e2112528ddba09e43d3dcc861 500 Gene3D G3DSA:3.40.605.10 1 266 7.9E-85 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CU254_RS31695 a50d032e2112528ddba09e43d3dcc861 500 SUPERFAMILY SSF53720 8 484 3.93E-149 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CU254_RS28195 eb25e2ac495d2a81f800caeea61a4477 282 SUPERFAMILY SSF53955 49 282 1.38E-88 T 28-03-2018 IPR023346 Lysozyme-like domain CU254_RS28195 eb25e2ac495d2a81f800caeea61a4477 282 Gene3D G3DSA:3.30.386.10 45 149 1.6E-49 T 28-03-2018 CU254_RS28195 eb25e2ac495d2a81f800caeea61a4477 282 Gene3D G3DSA:1.20.141.10 150 277 2.3E-53 T 28-03-2018 CU254_RS28195 eb25e2ac495d2a81f800caeea61a4477 282 PIRSF PIRSF036551 2 282 1.3E-106 T 28-03-2018 IPR000400 Glycoside hydrolase, family 46 GO:0005576|GO:0005975|GO:0016977 KEGG: 00520+3.2.1.132 CU254_RS28195 eb25e2ac495d2a81f800caeea61a4477 282 Pfam PF01374 Glycosyl hydrolase family 46 61 270 1.9E-98 T 28-03-2018 IPR000400 Glycoside hydrolase, family 46 GO:0005576|GO:0005975|GO:0016977 KEGG: 00520+3.2.1.132 CU254_RS28195 eb25e2ac495d2a81f800caeea61a4477 282 ProSitePatterns PS60000 Chitosanases families 46 and 80 active sites signature. 67 102 - T 28-03-2018 IPR000400 Glycoside hydrolase, family 46 GO:0005576|GO:0005975|GO:0016977 KEGG: 00520+3.2.1.132 CU254_RS10535 3ac078c2868343992ccfa331d938004d 160 SUPERFAMILY SSF50475 14 115 7.66E-16 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS10535 3ac078c2868343992ccfa331d938004d 160 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 18 98 2.1E-4 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CU254_RS10535 3ac078c2868343992ccfa331d938004d 160 Gene3D G3DSA:2.30.110.10 6 147 3.5E-14 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS19090 54c9aeb71b7f45f1bd1144220132e6b3 199 Gene3D G3DSA:1.10.10.60 6 68 2.6E-13 T 28-03-2018 CU254_RS19090 54c9aeb71b7f45f1bd1144220132e6b3 199 SUPERFAMILY SSF46689 12 69 2.14E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS19090 54c9aeb71b7f45f1bd1144220132e6b3 199 Gene3D G3DSA:1.10.357.10 69 199 4.1E-23 T 28-03-2018 CU254_RS19090 54c9aeb71b7f45f1bd1144220132e6b3 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 65 6.2E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS19090 54c9aeb71b7f45f1bd1144220132e6b3 199 SUPERFAMILY SSF48498 79 194 1.48E-27 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS19090 54c9aeb71b7f45f1bd1144220132e6b3 199 Pfam PF16859 Bacterial transcriptional repressor C-terminal 78 187 2.5E-29 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS22760 28946fb3e6936fbbf8fc687d6f8c34c8 133 Gene3D G3DSA:3.40.50.1010 1 128 7.1E-13 T 28-03-2018 IPR029060 PIN domain-like CU254_RS22760 28946fb3e6936fbbf8fc687d6f8c34c8 133 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 1 132 10.483 T 28-03-2018 IPR022907 VapC family GO:0004540 CU254_RS22760 28946fb3e6936fbbf8fc687d6f8c34c8 133 Pfam PF01850 PIN domain 1 119 2.5E-16 T 28-03-2018 IPR002716 PIN domain CU254_RS22760 28946fb3e6936fbbf8fc687d6f8c34c8 133 SUPERFAMILY SSF88723 1 128 7.85E-17 T 28-03-2018 IPR029060 PIN domain-like CU254_RS14880 75bcb6b7089548d4f35fa9767749e222 838 Pfam PF05977 Transmembrane secretion effector 11 410 5.0E-11 T 28-03-2018 IPR010290 Transmembrane secretion effector CU254_RS14880 75bcb6b7089548d4f35fa9767749e222 838 Pfam PF00990 Diguanylate cyclase, GGDEF domain 690 819 4.7E-11 T 28-03-2018 IPR000160 GGDEF domain CU254_RS14880 75bcb6b7089548d4f35fa9767749e222 838 SUPERFAMILY SSF55073 694 819 2.51E-16 T 28-03-2018 IPR029787 Nucleotide cyclase CU254_RS14880 75bcb6b7089548d4f35fa9767749e222 838 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 685 819 1.6E-15 T 28-03-2018 IPR000160 GGDEF domain CU254_RS14880 75bcb6b7089548d4f35fa9767749e222 838 Gene3D G3DSA:3.30.70.270 681 833 1.0E-18 T 28-03-2018 CU254_RS14880 75bcb6b7089548d4f35fa9767749e222 838 SMART SM00267 677 835 1.6E-7 T 28-03-2018 IPR000160 GGDEF domain CU254_RS14880 75bcb6b7089548d4f35fa9767749e222 838 Gene3D G3DSA:1.20.1250.20 6 203 7.3E-14 T 28-03-2018 CU254_RS14880 75bcb6b7089548d4f35fa9767749e222 838 SUPERFAMILY SSF103473 17 401 9.42E-28 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS14880 75bcb6b7089548d4f35fa9767749e222 838 Gene3D G3DSA:1.20.1250.20 209 409 3.0E-12 T 28-03-2018 CU254_RS32645 300421c49a8c1b44f645f354dbb05083 343 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS32645 300421c49a8c1b44f645f354dbb05083 343 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 239 336 2.5E-26 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CU254_RS32645 300421c49a8c1b44f645f354dbb05083 343 SMART SM00382 48 239 1.3E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS32645 300421c49a8c1b44f645f354dbb05083 343 Pfam PF00005 ABC transporter 40 189 1.1E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS32645 300421c49a8c1b44f645f354dbb05083 343 SUPERFAMILY SSF52540 12 261 8.2E-73 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS32645 300421c49a8c1b44f645f354dbb05083 343 Gene3D G3DSA:3.40.50.300 8 342 1.2E-82 T 28-03-2018 CU254_RS32645 300421c49a8c1b44f645f354dbb05083 343 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 241 303 1.8E-18 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CU254_RS27025 fc56505699af295dd71f7eb28753b15f 431 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 417 52.133 T 28-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 CU254_RS27025 fc56505699af295dd71f7eb28753b15f 431 SMART SM00382 115 268 4.4E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS27025 fc56505699af295dd71f7eb28753b15f 431 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 319 397 4.8E-16 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CU254_RS27025 fc56505699af295dd71f7eb28753b15f 431 SMART SM01086 319 413 1.6E-32 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CU254_RS27025 fc56505699af295dd71f7eb28753b15f 431 Gene3D G3DSA:1.10.8.60 319 411 1.2E-34 T 28-03-2018 CU254_RS27025 fc56505699af295dd71f7eb28753b15f 431 Gene3D G3DSA:3.40.50.300 53 317 1.6E-69 T 28-03-2018 CU254_RS27025 fc56505699af295dd71f7eb28753b15f 431 SUPERFAMILY SSF57716 11 46 1.38E-11 T 28-03-2018 CU254_RS27025 fc56505699af295dd71f7eb28753b15f 431 SMART SM00994 10 49 1.1E-23 T 28-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 CU254_RS27025 fc56505699af295dd71f7eb28753b15f 431 SUPERFAMILY SSF52540 59 407 8.38E-74 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS27025 fc56505699af295dd71f7eb28753b15f 431 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 9 413 2.5E-196 T 28-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 CU254_RS27025 fc56505699af295dd71f7eb28753b15f 431 Pfam PF07724 AAA domain (Cdc48 subfamily) 116 312 4.4E-50 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CU254_RS27025 fc56505699af295dd71f7eb28753b15f 431 Pfam PF06689 ClpX C4-type zinc finger 12 48 1.7E-20 T 28-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 CU254_RS20890 ec6103f338c6c3237a5d0ec4d88b7f67 402 SUPERFAMILY SSF89796 10 402 1.09E-125 T 28-03-2018 IPR023606 CoA-transferase family III domain CU254_RS20890 ec6103f338c6c3237a5d0ec4d88b7f67 402 Gene3D G3DSA:3.40.50.10540 6 402 3.3E-134 T 28-03-2018 IPR023606 CoA-transferase family III domain CU254_RS20890 ec6103f338c6c3237a5d0ec4d88b7f67 402 Pfam PF02515 CoA-transferase family III 12 379 3.3E-118 T 28-03-2018 IPR003673 CoA-transferase family III GO:0003824 CU254_RS10160 582e201f60e930b932c0587098d9b861 300 SUPERFAMILY SSF54637 135 298 4.79E-46 T 28-03-2018 IPR029069 HotDog domain CU254_RS10160 582e201f60e930b932c0587098d9b861 300 SUPERFAMILY SSF54637 23 133 4.82E-42 T 28-03-2018 IPR029069 HotDog domain CU254_RS10160 582e201f60e930b932c0587098d9b861 300 Pfam PF13622 Thioesterase-like superfamily 48 296 2.3E-59 T 28-03-2018 CU254_RS10160 582e201f60e930b932c0587098d9b861 300 Gene3D G3DSA:3.10.129.10 21 135 3.7E-44 T 28-03-2018 CU254_RS10160 582e201f60e930b932c0587098d9b861 300 Gene3D G3DSA:3.10.129.10 152 300 1.1E-49 T 28-03-2018 CU254_RS17165 8552082eac78dcd651be15923fe6a924 230 Pfam PF01670 Glycosyl hydrolase family 12 69 228 2.1E-21 T 28-03-2018 IPR002594 Glycoside hydrolase family 12 GO:0000272|GO:0008810 CU254_RS17165 8552082eac78dcd651be15923fe6a924 230 Gene3D G3DSA:2.60.120.180 27 230 6.9E-53 T 28-03-2018 IPR013319 Glycoside hydrolase family 11/12 GO:0004553 MetaCyc: PWY-6784 CU254_RS17165 8552082eac78dcd651be15923fe6a924 230 SUPERFAMILY SSF49899 30 228 2.49E-46 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CU254_RS01965 5581e21170d11e5cf18a5c2be5d8b6ad 277 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 272 5.3E-124 T 28-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 CU254_RS01965 5581e21170d11e5cf18a5c2be5d8b6ad 277 Gene3D G3DSA:2.30.30.30 120 196 3.7E-28 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 CU254_RS01965 5581e21170d11e5cf18a5c2be5d8b6ad 277 Gene3D G3DSA:2.40.50.140 1 115 8.9E-47 T 28-03-2018 CU254_RS01965 5581e21170d11e5cf18a5c2be5d8b6ad 277 ProSitePatterns PS00467 Ribosomal protein L2 signature. 219 230 - T 28-03-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS01965 5581e21170d11e5cf18a5c2be5d8b6ad 277 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 118 3.6E-33 T 28-03-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS01965 5581e21170d11e5cf18a5c2be5d8b6ad 277 SMART SM01383 42 119 7.8E-40 T 28-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS01965 5581e21170d11e5cf18a5c2be5d8b6ad 277 PIRSF PIRSF002158 4 274 1.2E-90 T 28-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS01965 5581e21170d11e5cf18a5c2be5d8b6ad 277 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 126 251 3.2E-53 T 28-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 CU254_RS01965 5581e21170d11e5cf18a5c2be5d8b6ad 277 SUPERFAMILY SSF50104 127 270 5.18E-54 T 28-03-2018 IPR008991 Translation protein SH3-like domain CU254_RS01965 5581e21170d11e5cf18a5c2be5d8b6ad 277 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 272 46.954 T 28-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 CU254_RS01965 5581e21170d11e5cf18a5c2be5d8b6ad 277 SMART SM01382 125 253 3.0E-86 T 28-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 CU254_RS01965 5581e21170d11e5cf18a5c2be5d8b6ad 277 SUPERFAMILY SSF50249 3 126 2.64E-49 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CU254_RS01965 5581e21170d11e5cf18a5c2be5d8b6ad 277 Gene3D G3DSA:4.10.950.10 198 272 7.6E-30 T 28-03-2018 IPR014726 Ribosomal protein L2, domain 3 CU254_RS09575 a2b17745c9c4b790976f1ea4ca20975e 395 SUPERFAMILY SSF52467 56 174 4.58E-5 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CU254_RS09575 a2b17745c9c4b790976f1ea4ca20975e 395 Gene3D G3DSA:3.40.50.1220 48 256 1.7E-4 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CU254_RS09575 a2b17745c9c4b790976f1ea4ca20975e 395 Pfam PF13289 SIR2-like domain 76 199 2.5E-17 T 28-03-2018 CU254_RS25755 aa3c918655cc6c084981c0cdbf0e7fea 696 Gene3D G3DSA:3.30.365.10 156 259 1.8E-31 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CU254_RS25755 aa3c918655cc6c084981c0cdbf0e7fea 696 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 24 127 4.8E-13 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CU254_RS25755 aa3c918655cc6c084981c0cdbf0e7fea 696 Gene3D G3DSA:3.30.365.10 510 694 2.2E-46 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CU254_RS25755 aa3c918655cc6c084981c0cdbf0e7fea 696 SMART SM01008 24 128 1.4E-20 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CU254_RS25755 aa3c918655cc6c084981c0cdbf0e7fea 696 SUPERFAMILY SSF54665 6 130 5.63E-24 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CU254_RS25755 aa3c918655cc6c084981c0cdbf0e7fea 696 Gene3D G3DSA:3.90.1170.50 8 128 3.3E-24 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CU254_RS25755 aa3c918655cc6c084981c0cdbf0e7fea 696 SUPERFAMILY SSF56003 133 691 3.01E-159 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CU254_RS25755 aa3c918655cc6c084981c0cdbf0e7fea 696 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 534 628 4.9E-22 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CU254_RS25755 aa3c918655cc6c084981c0cdbf0e7fea 696 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 156 518 1.1E-85 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CU254_RS25755 aa3c918655cc6c084981c0cdbf0e7fea 696 Gene3D G3DSA:3.30.365.10 432 509 6.8E-21 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CU254_RS25755 aa3c918655cc6c084981c0cdbf0e7fea 696 Gene3D G3DSA:3.30.365.10 260 411 1.2E-33 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CU254_RS01045 304d9a81d4a112552e26e8e91f7ece3e 412 Pfam PF00512 His Kinase A (phospho-acceptor) domain 148 212 1.5E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS01045 304d9a81d4a112552e26e8e91f7ece3e 412 SMART SM00388 147 213 2.7E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS01045 304d9a81d4a112552e26e8e91f7ece3e 412 Gene3D G3DSA:3.30.565.10 217 379 4.4E-41 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS01045 304d9a81d4a112552e26e8e91f7ece3e 412 PRINTS PR00344 Bacterial sensor protein C-terminal signature 330 348 2.2E-20 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS01045 304d9a81d4a112552e26e8e91f7ece3e 412 PRINTS PR00344 Bacterial sensor protein C-terminal signature 295 309 2.2E-20 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS01045 304d9a81d4a112552e26e8e91f7ece3e 412 PRINTS PR00344 Bacterial sensor protein C-terminal signature 354 367 2.2E-20 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS01045 304d9a81d4a112552e26e8e91f7ece3e 412 PRINTS PR00344 Bacterial sensor protein C-terminal signature 313 323 2.2E-20 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS01045 304d9a81d4a112552e26e8e91f7ece3e 412 SUPERFAMILY SSF55874 203 369 1.57E-44 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS01045 304d9a81d4a112552e26e8e91f7ece3e 412 SUPERFAMILY SSF47384 138 211 1.33E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS01045 304d9a81d4a112552e26e8e91f7ece3e 412 Gene3D G3DSA:1.10.287.130 138 209 2.9E-12 T 28-03-2018 CU254_RS01045 304d9a81d4a112552e26e8e91f7ece3e 412 SMART SM00387 258 370 1.9E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS01045 304d9a81d4a112552e26e8e91f7ece3e 412 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 258 368 8.4E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS24570 d734e3e2a4ac6ca854ef1a8bd06cb002 277 Pfam PF13460 NAD(P)H-binding 7 175 2.4E-24 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS24570 d734e3e2a4ac6ca854ef1a8bd06cb002 277 Gene3D G3DSA:3.40.50.720 1 253 7.4E-28 T 28-03-2018 CU254_RS24570 d734e3e2a4ac6ca854ef1a8bd06cb002 277 SUPERFAMILY SSF51735 2 244 4.03E-50 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS18100 421ad6a80b2237eba094ce78183064fb 254 SMART SM00422 3 72 2.8E-31 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS18100 421ad6a80b2237eba094ce78183064fb 254 Gene3D G3DSA:1.10.1660.10 59 117 2.8E-10 T 28-03-2018 CU254_RS18100 421ad6a80b2237eba094ce78183064fb 254 Gene3D G3DSA:1.10.490.50 159 252 1.6E-15 T 28-03-2018 CU254_RS18100 421ad6a80b2237eba094ce78183064fb 254 ProSitePatterns PS00552 MerR-type HTH domain signature. 6 28 - T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS18100 421ad6a80b2237eba094ce78183064fb 254 Pfam PF00376 MerR family regulatory protein 4 41 2.8E-16 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS18100 421ad6a80b2237eba094ce78183064fb 254 Pfam PF09278 MerR, DNA binding 46 99 2.5E-5 T 28-03-2018 IPR015358 Transcription regulator MerR, DNA binding CU254_RS18100 421ad6a80b2237eba094ce78183064fb 254 SUPERFAMILY SSF89082 158 249 5.1E-12 T 28-03-2018 IPR012925 TipAS antibiotic-recognition domain CU254_RS18100 421ad6a80b2237eba094ce78183064fb 254 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 28 1.2E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS18100 421ad6a80b2237eba094ce78183064fb 254 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 1.2E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS18100 421ad6a80b2237eba094ce78183064fb 254 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 4 15 1.2E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS18100 421ad6a80b2237eba094ce78183064fb 254 Pfam PF07739 TipAS antibiotic-recognition domain 132 247 4.1E-19 T 28-03-2018 IPR012925 TipAS antibiotic-recognition domain CU254_RS18100 421ad6a80b2237eba094ce78183064fb 254 Gene3D G3DSA:1.10.1660.10 1 58 7.7E-24 T 28-03-2018 CU254_RS18100 421ad6a80b2237eba094ce78183064fb 254 SUPERFAMILY SSF46955 3 105 4.03E-28 T 28-03-2018 IPR009061 Putative DNA-binding domain CU254_RS37480 cb106b8b57f69e3a5e00729f5a02cdac 101 SUPERFAMILY SSF49478 27 78 9.81E-6 T 28-03-2018 CU254_RS37480 cb106b8b57f69e3a5e00729f5a02cdac 101 Gene3D G3DSA:2.60.40.1120 17 100 1.8E-7 T 28-03-2018 CU254_RS37480 cb106b8b57f69e3a5e00729f5a02cdac 101 Pfam PF07210 Protein of unknown function (DUF1416) 5 100 5.8E-37 T 28-03-2018 IPR010814 Protein of unknown function DUF1416 CU254_RS34775 bb1d420cffd51d80d8084927c663b180 511 SUPERFAMILY SSF51905 24 251 2.1E-32 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS34775 bb1d420cffd51d80d8084927c663b180 511 SUPERFAMILY SSF51905 287 348 2.1E-32 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS34775 bb1d420cffd51d80d8084927c663b180 511 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 37 47 4.2E-29 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CU254_RS34775 bb1d420cffd51d80d8084927c663b180 511 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 369 381 4.2E-29 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CU254_RS34775 bb1d420cffd51d80d8084927c663b180 511 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 24 36 4.2E-29 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CU254_RS34775 bb1d420cffd51d80d8084927c663b180 511 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 99 111 4.2E-29 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CU254_RS34775 bb1d420cffd51d80d8084927c663b180 511 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 53 65 4.2E-29 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CU254_RS34775 bb1d420cffd51d80d8084927c663b180 511 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 339 345 4.2E-29 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CU254_RS34775 bb1d420cffd51d80d8084927c663b180 511 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 29 46 - T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CU254_RS34775 bb1d420cffd51d80d8084927c663b180 511 Gene3D G3DSA:3.50.50.60 4 416 7.3E-54 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS34775 bb1d420cffd51d80d8084927c663b180 511 Pfam PF01266 FAD dependent oxidoreductase 25 381 1.6E-51 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CU254_RS34775 bb1d420cffd51d80d8084927c663b180 511 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 403 507 2.1E-19 T 28-03-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CU254_RS34775 bb1d420cffd51d80d8084927c663b180 511 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 374 384 - T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CU254_RS03920 b1f2ccc82b9017d54435da74b898abd4 209 Pfam PF01914 MarC family integral membrane protein 10 205 3.1E-47 T 28-03-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 CU254_RS03920 b1f2ccc82b9017d54435da74b898abd4 209 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 10 200 5.0E-43 T 28-03-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 CU254_RS23205 198314ea35a282e54d900c847461aa50 123 SUPERFAMILY SSF55781 1 106 5.62E-26 T 28-03-2018 IPR029016 GAF domain-like CU254_RS23205 198314ea35a282e54d900c847461aa50 123 Pfam PF01614 Bacterial transcriptional regulator 1 106 4.7E-23 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal CU254_RS23205 198314ea35a282e54d900c847461aa50 123 Gene3D G3DSA:3.30.450.40 1 121 8.1E-27 T 28-03-2018 IPR029016 GAF domain-like CU254_RS14145 996fdd93e34036c5d117a30554711a2b 1043 SUPERFAMILY SSF48208 266 523 9.18E-23 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CU254_RS14145 996fdd93e34036c5d117a30554711a2b 1043 SUPERFAMILY SSF48208 550 717 9.18E-23 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CU254_RS14145 996fdd93e34036c5d117a30554711a2b 1043 Gene3D G3DSA:2.70.98.10 26 327 6.8E-96 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 CU254_RS14145 996fdd93e34036c5d117a30554711a2b 1043 Gene3D G3DSA:1.20.1050.60 352 442 1.7E-22 T 28-03-2018 CU254_RS14145 996fdd93e34036c5d117a30554711a2b 1043 TIGRFAM TIGR01180 aman2_put: putative alpha-1,2-mannosidase 14 740 6.5E-159 T 28-03-2018 IPR005887 Alpha-1,2-mannosidase, putative CU254_RS14145 996fdd93e34036c5d117a30554711a2b 1043 Gene3D G3DSA:1.20.1610.10 448 600 3.7E-47 T 28-03-2018 CU254_RS14145 996fdd93e34036c5d117a30554711a2b 1043 Gene3D G3DSA:3.30.2080.10 601 749 5.1E-56 T 28-03-2018 CU254_RS14145 996fdd93e34036c5d117a30554711a2b 1043 Pfam PF07971 Glycosyl hydrolase family 92 245 736 2.9E-158 T 28-03-2018 IPR012939 Glycosyl hydrolase family 92 CU254_RS01590 b2172bc58dbbbe7993663b26b395276a 410 Pfam PF08484 C-methyltransferase C-terminal domain 244 402 1.3E-61 T 28-03-2018 IPR013691 C-methyltransferase CU254_RS01590 b2172bc58dbbbe7993663b26b395276a 410 Pfam PF08421 Putative zinc binding domain 4 65 9.5E-21 T 28-03-2018 IPR013630 Methyltransferase putative zinc binding domain CU254_RS01590 b2172bc58dbbbe7993663b26b395276a 410 Pfam PF13489 Methyltransferase domain 82 238 2.1E-14 T 28-03-2018 CU254_RS01590 b2172bc58dbbbe7993663b26b395276a 410 SUPERFAMILY SSF53335 59 249 2.25E-22 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS01590 b2172bc58dbbbe7993663b26b395276a 410 Gene3D G3DSA:3.40.50.150 64 255 7.0E-27 T 28-03-2018 CU254_RS34425 67a1a975b837da779a1292b4a7fe55b7 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 4.4E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS34425 67a1a975b837da779a1292b4a7fe55b7 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 4.4E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS34425 67a1a975b837da779a1292b4a7fe55b7 199 SUPERFAMILY SSF48498 91 198 3.06E-9 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS34425 67a1a975b837da779a1292b4a7fe55b7 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 66 6.7E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS34425 67a1a975b837da779a1292b4a7fe55b7 199 Gene3D G3DSA:1.10.10.60 1 42 1.4E-17 T 28-03-2018 CU254_RS34425 67a1a975b837da779a1292b4a7fe55b7 199 Gene3D G3DSA:1.10.357.10 76 199 3.1E-8 T 28-03-2018 CU254_RS34425 67a1a975b837da779a1292b4a7fe55b7 199 SUPERFAMILY SSF46689 8 92 4.0E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS34425 67a1a975b837da779a1292b4a7fe55b7 199 Gene3D G3DSA:1.10.260.40 43 75 4.9E-13 T 28-03-2018 CU254_RS36265 19b2b2cde672d7300efa2c07857f1cd2 243 Pfam PF13460 NAD(P)H-binding 8 129 3.9E-14 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS36265 19b2b2cde672d7300efa2c07857f1cd2 243 SUPERFAMILY SSF51735 1 209 4.89E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS36265 19b2b2cde672d7300efa2c07857f1cd2 243 Gene3D G3DSA:3.40.50.720 1 239 1.7E-26 T 28-03-2018 CU254_RS35460 b1ffdc2d61e6a5355fb2334cde5d8b3d 188 Pfam PF01327 Polypeptide deformylase 4 156 1.5E-45 T 28-03-2018 IPR023635 Peptide deformylase CU254_RS35460 b1ffdc2d61e6a5355fb2334cde5d8b3d 188 Hamap MF_00163 Peptide deformylase [def]. 2 170 28.656 T 28-03-2018 IPR023635 Peptide deformylase CU254_RS35460 b1ffdc2d61e6a5355fb2334cde5d8b3d 188 Gene3D G3DSA:3.90.45.10 4 178 7.9E-61 T 28-03-2018 IPR023635 Peptide deformylase CU254_RS35460 b1ffdc2d61e6a5355fb2334cde5d8b3d 188 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 8 165 5.1E-40 T 28-03-2018 IPR023635 Peptide deformylase CU254_RS35460 b1ffdc2d61e6a5355fb2334cde5d8b3d 188 PIRSF PIRSF004749 1 178 1.4E-46 T 28-03-2018 IPR023635 Peptide deformylase CU254_RS35460 b1ffdc2d61e6a5355fb2334cde5d8b3d 188 SUPERFAMILY SSF56420 3 182 4.06E-55 T 28-03-2018 IPR023635 Peptide deformylase CU254_RS35460 b1ffdc2d61e6a5355fb2334cde5d8b3d 188 PRINTS PR01576 Peptide deformylase signature 33 62 1.1E-31 T 28-03-2018 IPR023635 Peptide deformylase CU254_RS35460 b1ffdc2d61e6a5355fb2334cde5d8b3d 188 PRINTS PR01576 Peptide deformylase signature 109 127 1.1E-31 T 28-03-2018 IPR023635 Peptide deformylase CU254_RS35460 b1ffdc2d61e6a5355fb2334cde5d8b3d 188 PRINTS PR01576 Peptide deformylase signature 128 157 1.1E-31 T 28-03-2018 IPR023635 Peptide deformylase CU254_RS35460 b1ffdc2d61e6a5355fb2334cde5d8b3d 188 PRINTS PR01576 Peptide deformylase signature 97 108 1.1E-31 T 28-03-2018 IPR023635 Peptide deformylase CU254_RS01500 9853cf5b56c0796b8ae1d86bcc323112 406 Pfam PF13439 Glycosyltransferase Family 4 23 202 2.5E-17 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CU254_RS01500 9853cf5b56c0796b8ae1d86bcc323112 406 Pfam PF13692 Glycosyl transferases group 1 219 365 8.1E-16 T 28-03-2018 CU254_RS01500 9853cf5b56c0796b8ae1d86bcc323112 406 Gene3D G3DSA:3.40.50.2000 28 210 6.8E-16 T 28-03-2018 CU254_RS01500 9853cf5b56c0796b8ae1d86bcc323112 406 Gene3D G3DSA:3.40.50.2000 211 386 8.3E-27 T 28-03-2018 CU254_RS01500 9853cf5b56c0796b8ae1d86bcc323112 406 SUPERFAMILY SSF53756 23 401 7.85E-55 T 28-03-2018 CU254_RS40520 3388c0c5e6e03b3bc3000b8dc2eab980 529 Gene3D G3DSA:3.30.450.20 198 308 1.2E-8 T 28-03-2018 CU254_RS40520 3388c0c5e6e03b3bc3000b8dc2eab980 529 Gene3D G3DSA:3.30.450.20 26 158 8.4E-24 T 28-03-2018 CU254_RS40520 3388c0c5e6e03b3bc3000b8dc2eab980 529 Gene3D G3DSA:1.10.287.130 309 366 3.8E-19 T 28-03-2018 CU254_RS40520 3388c0c5e6e03b3bc3000b8dc2eab980 529 Pfam PF17203 Single cache domain 3 30 165 2.8E-25 T 28-03-2018 IPR033463 Single cache domain 3 CU254_RS40520 3388c0c5e6e03b3bc3000b8dc2eab980 529 SUPERFAMILY SSF103190 32 163 3.26E-29 T 28-03-2018 IPR029151 Periplasmic sensor domain-like CU254_RS40520 3388c0c5e6e03b3bc3000b8dc2eab980 529 SMART SM00387 408 521 1.2E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS40520 3388c0c5e6e03b3bc3000b8dc2eab980 529 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 313 360 1.4E-11 T 28-03-2018 CU254_RS40520 3388c0c5e6e03b3bc3000b8dc2eab980 529 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 409 514 8.8E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS40520 3388c0c5e6e03b3bc3000b8dc2eab980 529 SUPERFAMILY SSF55874 377 519 1.11E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS40520 3388c0c5e6e03b3bc3000b8dc2eab980 529 PRINTS PR00344 Bacterial sensor protein C-terminal signature 449 463 3.9E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS40520 3388c0c5e6e03b3bc3000b8dc2eab980 529 PRINTS PR00344 Bacterial sensor protein C-terminal signature 479 497 3.9E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS40520 3388c0c5e6e03b3bc3000b8dc2eab980 529 PRINTS PR00344 Bacterial sensor protein C-terminal signature 505 518 3.9E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS40520 3388c0c5e6e03b3bc3000b8dc2eab980 529 Gene3D G3DSA:3.30.565.10 373 529 1.4E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS40520 3388c0c5e6e03b3bc3000b8dc2eab980 529 SUPERFAMILY SSF55890 314 362 1.03E-11 T 28-03-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 CU254_RS22605 6870eba6a1f297eed1f70700be3ae11a 478 Pfam PF07690 Major Facilitator Superfamily 17 409 4.0E-43 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS22605 6870eba6a1f297eed1f70700be3ae11a 478 Gene3D G3DSA:1.20.1250.20 252 478 1.1E-22 T 28-03-2018 CU254_RS22605 6870eba6a1f297eed1f70700be3ae11a 478 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 12 426 2.5E-72 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CU254_RS22605 6870eba6a1f297eed1f70700be3ae11a 478 Gene3D G3DSA:1.20.1250.20 4 187 9.5E-29 T 28-03-2018 CU254_RS22605 6870eba6a1f297eed1f70700be3ae11a 478 SUPERFAMILY SSF103473 5 185 1.96E-37 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS22605 6870eba6a1f297eed1f70700be3ae11a 478 Gene3D G3DSA:1.20.1250.20 188 251 0.22 T 28-03-2018 CU254_RS22605 6870eba6a1f297eed1f70700be3ae11a 478 SUPERFAMILY SSF103473 187 464 2.49E-24 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS03800 d0e6993ade7568e2f71bb63c4006a62d 436 Gene3D G3DSA:1.25.60.10 164 273 6.6E-19 T 28-03-2018 CU254_RS03800 d0e6993ade7568e2f71bb63c4006a62d 436 SMART SM00924 182 285 6.4E-28 T 28-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain CU254_RS03800 d0e6993ade7568e2f71bb63c4006a62d 436 SMART SM00116 361 409 0.0072 T 28-03-2018 IPR000644 CBS domain CU254_RS03800 d0e6993ade7568e2f71bb63c4006a62d 436 Pfam PF05239 PRC-barrel domain 6 70 3.5E-5 T 28-03-2018 IPR027275 PRC-barrel domain CU254_RS03800 d0e6993ade7568e2f71bb63c4006a62d 436 Gene3D G3DSA:3.10.580.10 274 416 3.3E-20 T 28-03-2018 CU254_RS03800 d0e6993ade7568e2f71bb63c4006a62d 436 Gene3D G3DSA:2.30.30.240 7 77 2.5E-12 T 28-03-2018 CU254_RS03800 d0e6993ade7568e2f71bb63c4006a62d 436 Pfam PF00571 CBS domain 359 409 3.9E-5 T 28-03-2018 IPR000644 CBS domain CU254_RS03800 d0e6993ade7568e2f71bb63c4006a62d 436 Pfam PF00571 CBS domain 286 347 1.7E-4 T 28-03-2018 IPR000644 CBS domain CU254_RS03800 d0e6993ade7568e2f71bb63c4006a62d 436 SUPERFAMILY SSF54631 284 415 2.15E-24 T 28-03-2018 CU254_RS03800 d0e6993ade7568e2f71bb63c4006a62d 436 SUPERFAMILY SSF50346 7 89 3.61E-11 T 28-03-2018 IPR011033 PRC-barrel-like CU254_RS03800 d0e6993ade7568e2f71bb63c4006a62d 436 SUPERFAMILY SSF158791 172 281 5.75E-26 T 28-03-2018 CU254_RS03800 d0e6993ade7568e2f71bb63c4006a62d 436 Pfam PF03448 MgtE intracellular N domain 182 283 1.5E-21 T 28-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain CU254_RS39765 186b000ac26c096a1e6a56c2cab2d3a8 398 SUPERFAMILY SSF52540 18 257 1.68E-74 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS39765 186b000ac26c096a1e6a56c2cab2d3a8 398 Gene3D G3DSA:3.40.50.300 13 275 1.4E-71 T 28-03-2018 CU254_RS39765 186b000ac26c096a1e6a56c2cab2d3a8 398 SUPERFAMILY SSF54631 267 388 1.01E-7 T 28-03-2018 CU254_RS39765 186b000ac26c096a1e6a56c2cab2d3a8 398 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS39765 186b000ac26c096a1e6a56c2cab2d3a8 398 SMART SM00382 44 231 8.3E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS39765 186b000ac26c096a1e6a56c2cab2d3a8 398 Pfam PF00005 ABC transporter 36 181 1.5E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS39765 186b000ac26c096a1e6a56c2cab2d3a8 398 Gene3D G3DSA:3.10.580.10 276 394 8.2E-8 T 28-03-2018 CU254_RS17800 67a86bb1aa14878eebf76afea17da60f 269 Gene3D G3DSA:3.90.226.10 11 265 1.2E-60 T 28-03-2018 CU254_RS17800 67a86bb1aa14878eebf76afea17da60f 269 SUPERFAMILY SSF52096 16 257 8.16E-65 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS17800 67a86bb1aa14878eebf76afea17da60f 269 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 110 130 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CU254_RS17800 67a86bb1aa14878eebf76afea17da60f 269 Pfam PF00378 Enoyl-CoA hydratase/isomerase 26 259 2.1E-40 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CU254_RS17085 01223c4b2cd2da6e556a19117a079880 517 Pfam PF13556 PucR C-terminal helix-turn-helix domain 443 500 1.1E-22 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CU254_RS17085 01223c4b2cd2da6e556a19117a079880 517 Gene3D G3DSA:1.10.10.60 410 479 5.5E-8 T 28-03-2018 CU254_RS17275 692dc74cbab22858268facb64eba6975 2008 Gene3D G3DSA:3.40.366.10 754 944 3.4E-14 T 28-03-2018 CU254_RS17275 692dc74cbab22858268facb64eba6975 2008 SUPERFAMILY SSF47336 1177 1259 2.49E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS17275 692dc74cbab22858268facb64eba6975 2008 SUPERFAMILY SSF53901 439 659 2.71E-58 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS17275 692dc74cbab22858268facb64eba6975 2008 SUPERFAMILY SSF53901 256 375 2.71E-58 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS17275 692dc74cbab22858268facb64eba6975 2008 Gene3D G3DSA:3.30.70.250 945 986 1.6E-14 T 28-03-2018 CU254_RS17275 692dc74cbab22858268facb64eba6975 2008 Gene3D G3DSA:3.40.50.720 1414 1641 1.5E-31 T 28-03-2018 CU254_RS17275 692dc74cbab22858268facb64eba6975 2008 Pfam PF08659 KR domain 1422 1591 1.2E-18 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS17275 692dc74cbab22858268facb64eba6975 2008 Pfam PF00698 Acyl transferase domain 862 1066 1.7E-23 T 28-03-2018 IPR014043 Acyl transferase CU254_RS17275 692dc74cbab22858268facb64eba6975 2008 SUPERFAMILY SSF54637 1681 1748 1.96E-7 T 28-03-2018 IPR029069 HotDog domain CU254_RS17275 692dc74cbab22858268facb64eba6975 2008 SUPERFAMILY SSF51735 1416 1642 8.5E-27 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS17275 692dc74cbab22858268facb64eba6975 2008 Gene3D G3DSA:1.10.1200.10 1165 1261 3.9E-10 T 28-03-2018 CU254_RS17275 692dc74cbab22858268facb64eba6975 2008 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 669 752 1.4E-9 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS17275 692dc74cbab22858268facb64eba6975 2008 Gene3D G3DSA:3.40.47.10 250 554 5.1E-60 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS17275 692dc74cbab22858268facb64eba6975 2008 Pfam PF14765 Polyketide synthase dehydratase 1666 1914 9.1E-35 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS17275 692dc74cbab22858268facb64eba6975 2008 SUPERFAMILY SSF52151 996 1083 2.01E-35 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CU254_RS17275 692dc74cbab22858268facb64eba6975 2008 SUPERFAMILY SSF52151 828 933 2.01E-35 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CU254_RS17275 692dc74cbab22858268facb64eba6975 2008 Gene3D G3DSA:3.10.129.10 1657 1769 3.8E-14 T 28-03-2018 CU254_RS17275 692dc74cbab22858268facb64eba6975 2008 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1420 1593 8.6E-10 T 28-03-2018 CU254_RS17275 692dc74cbab22858268facb64eba6975 2008 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 550 661 4.3E-30 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CU254_RS17275 692dc74cbab22858268facb64eba6975 2008 Gene3D G3DSA:3.40.366.10 987 1090 1.1E-20 T 28-03-2018 CU254_RS17275 692dc74cbab22858268facb64eba6975 2008 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 258 542 2.1E-50 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CU254_RS17275 692dc74cbab22858268facb64eba6975 2008 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 831 1111 1.2E-22 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CU254_RS17275 692dc74cbab22858268facb64eba6975 2008 SMART SM00825 Beta-ketoacyl synthase 260 711 2.7E-58 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CU254_RS17275 692dc74cbab22858268facb64eba6975 2008 Gene3D G3DSA:3.40.47.10 555 709 7.7E-44 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS17275 692dc74cbab22858268facb64eba6975 2008 SUPERFAMILY SSF55048 934 995 1.96E-9 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CU254_RS17275 692dc74cbab22858268facb64eba6975 2008 Pfam PF00550 Phosphopantetheine attachment site 1181 1247 4.6E-5 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS29750 d632f388b149e9b275e4e3af33c7048e 1147 SUPERFAMILY SSF52518 17 192 2.35E-10 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS29750 d632f388b149e9b275e4e3af33c7048e 1147 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 440 531 7.8E-8 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CU254_RS29750 d632f388b149e9b275e4e3af33c7048e 1147 SUPERFAMILY SSF53323 705 934 3.14E-20 T 28-03-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CU254_RS29750 d632f388b149e9b275e4e3af33c7048e 1147 SUPERFAMILY SSF52518 420 604 2.06E-13 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS29750 d632f388b149e9b275e4e3af33c7048e 1147 Gene3D G3DSA:3.40.50.970 375 622 3.3E-29 T 28-03-2018 CU254_RS29750 d632f388b149e9b275e4e3af33c7048e 1147 Gene3D G3DSA:3.40.50.970 1 223 2.7E-16 T 28-03-2018 CU254_RS29750 d632f388b149e9b275e4e3af33c7048e 1147 Gene3D G3DSA:3.40.920.10 701 904 6.7E-43 T 28-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CU254_RS29750 d632f388b149e9b275e4e3af33c7048e 1147 SUPERFAMILY SSF52922 262 390 1.98E-7 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CU254_RS29750 d632f388b149e9b275e4e3af33c7048e 1147 Gene3D G3DSA:3.40.50.920 260 374 0.0053 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CU254_RS29750 d632f388b149e9b275e4e3af33c7048e 1147 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 712 898 7.4E-22 T 28-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CU254_RS27465 301bebe0c8045ff44fc30de980ebca4d 146 Pfam PF12680 SnoaL-like domain 24 129 1.8E-17 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CU254_RS27465 301bebe0c8045ff44fc30de980ebca4d 146 Gene3D G3DSA:3.10.450.50 10 145 8.7E-23 T 28-03-2018 CU254_RS27465 301bebe0c8045ff44fc30de980ebca4d 146 SUPERFAMILY SSF54427 15 140 1.84E-26 T 28-03-2018 IPR032710 NTF2-like domain CU254_RS10430 c6b0527b8430784fa60c7103d31e662b 341 Gene3D G3DSA:3.40.50.80 105 228 8.2E-27 T 28-03-2018 CU254_RS10430 c6b0527b8430784fa60c7103d31e662b 341 Gene3D G3DSA:2.40.30.10 1 103 4.5E-22 T 28-03-2018 CU254_RS10430 c6b0527b8430784fa60c7103d31e662b 341 Pfam PF00970 Oxidoreductase FAD-binding domain 7 104 7.6E-11 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CU254_RS10430 c6b0527b8430784fa60c7103d31e662b 341 PRINTS PR00410 Phenol hydroxylase reductase family signature 36 48 9.2E-10 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CU254_RS10430 c6b0527b8430784fa60c7103d31e662b 341 PRINTS PR00410 Phenol hydroxylase reductase family signature 198 206 9.2E-10 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CU254_RS10430 c6b0527b8430784fa60c7103d31e662b 341 PRINTS PR00410 Phenol hydroxylase reductase family signature 114 133 9.2E-10 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CU254_RS10430 c6b0527b8430784fa60c7103d31e662b 341 Gene3D G3DSA:3.10.20.30 229 341 5.2E-29 T 28-03-2018 IPR012675 Beta-grasp domain CU254_RS10430 c6b0527b8430784fa60c7103d31e662b 341 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 138 147 4.6E-8 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CU254_RS10430 c6b0527b8430784fa60c7103d31e662b 341 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 198 206 4.6E-8 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CU254_RS10430 c6b0527b8430784fa60c7103d31e662b 341 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 56 63 4.6E-8 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CU254_RS10430 c6b0527b8430784fa60c7103d31e662b 341 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 114 133 4.6E-8 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CU254_RS10430 c6b0527b8430784fa60c7103d31e662b 341 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 289 297 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CU254_RS10430 c6b0527b8430784fa60c7103d31e662b 341 Pfam PF00175 Oxidoreductase NAD-binding domain 116 212 2.7E-14 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CU254_RS10430 c6b0527b8430784fa60c7103d31e662b 341 SUPERFAMILY SSF63380 3 104 1.19E-24 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CU254_RS10430 c6b0527b8430784fa60c7103d31e662b 341 SUPERFAMILY SSF52343 95 228 3.4E-31 T 28-03-2018 CU254_RS10430 c6b0527b8430784fa60c7103d31e662b 341 SUPERFAMILY SSF54292 221 335 2.62E-26 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CU254_RS10430 c6b0527b8430784fa60c7103d31e662b 341 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 258 331 5.5E-14 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CU254_RS32140 72e6c530944b35edd78d5505c0b08f54 661 SUPERFAMILY SSF51230 582 654 2.88E-20 T 28-03-2018 IPR011053 Single hybrid motif CU254_RS32140 72e6c530944b35edd78d5505c0b08f54 661 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 611 628 - T 28-03-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CU254_RS32140 72e6c530944b35edd78d5505c0b08f54 661 SUPERFAMILY SSF52440 2 113 2.95E-47 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CU254_RS32140 72e6c530944b35edd78d5505c0b08f54 661 Gene3D G3DSA:3.30.1490.20 124 209 2.3E-20 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CU254_RS32140 72e6c530944b35edd78d5505c0b08f54 661 Pfam PF02785 Biotin carboxylase C-terminal domain 338 444 1.4E-34 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CU254_RS32140 72e6c530944b35edd78d5505c0b08f54 661 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 288 295 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CU254_RS32140 72e6c530944b35edd78d5505c0b08f54 661 Gene3D G3DSA:3.40.50.20 1 123 6.3E-53 T 28-03-2018 CU254_RS32140 72e6c530944b35edd78d5505c0b08f54 661 Gene3D G3DSA:2.40.50.100 586 656 6.2E-18 T 28-03-2018 CU254_RS32140 72e6c530944b35edd78d5505c0b08f54 661 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CU254_RS32140 72e6c530944b35edd78d5505c0b08f54 661 Gene3D G3DSA:3.30.470.20 210 447 3.8E-103 T 28-03-2018 CU254_RS32140 72e6c530944b35edd78d5505c0b08f54 661 SMART SM00878 338 444 3.9E-52 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CU254_RS32140 72e6c530944b35edd78d5505c0b08f54 661 SUPERFAMILY SSF51246 333 449 3.19E-37 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CU254_RS32140 72e6c530944b35edd78d5505c0b08f54 661 SUPERFAMILY SSF56059 83 350 1.2E-67 T 28-03-2018 CU254_RS32140 72e6c530944b35edd78d5505c0b08f54 661 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 110 6.1E-45 T 28-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CU254_RS32140 72e6c530944b35edd78d5505c0b08f54 661 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 324 1.2E-75 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CU254_RS32140 72e6c530944b35edd78d5505c0b08f54 661 Pfam PF00364 Biotin-requiring enzyme 589 653 2.7E-16 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CU254_RS02585 bd63eebeb972470bc5b3ca1162d805ea 106 Gene3D G3DSA:3.40.50.280 2 99 8.5E-9 T 28-03-2018 CU254_RS02585 bd63eebeb972470bc5b3ca1162d805ea 106 SUPERFAMILY SSF52242 19 57 3.4E-9 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CU254_RS32285 c72f804bfbc342d49d14ceeb902d9749 393 SMART SM01274 22 155 4.3E-73 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CU254_RS32285 c72f804bfbc342d49d14ceeb902d9749 393 Gene3D G3DSA:3.40.50.720 165 393 2.3E-67 T 28-03-2018 CU254_RS32285 c72f804bfbc342d49d14ceeb902d9749 393 Gene3D G3DSA:3.40.50.10380 9 164 1.7E-32 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CU254_RS32285 c72f804bfbc342d49d14ceeb902d9749 393 SUPERFAMILY SSF51735 167 391 3.43E-65 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS32285 c72f804bfbc342d49d14ceeb902d9749 393 SUPERFAMILY SSF53223 16 165 1.94E-50 T 28-03-2018 CU254_RS32285 c72f804bfbc342d49d14ceeb902d9749 393 Pfam PF03949 Malic enzyme, NAD binding domain 169 386 4.6E-19 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CU254_RS32285 c72f804bfbc342d49d14ceeb902d9749 393 SMART SM00919 167 387 1.8E-107 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CU254_RS32285 c72f804bfbc342d49d14ceeb902d9749 393 PIRSF PIRSF000106 14 393 2.8E-70 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CU254_RS32285 c72f804bfbc342d49d14ceeb902d9749 393 Pfam PF00390 Malic enzyme, N-terminal domain 24 155 2.1E-25 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CU254_RS18125 bd195ccb567fdf2e093f52e06d3714f8 418 SUPERFAMILY SSF103473 10 392 2.88E-32 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS18125 bd195ccb567fdf2e093f52e06d3714f8 418 Gene3D G3DSA:1.20.1250.20 1 198 2.7E-18 T 28-03-2018 CU254_RS18125 bd195ccb567fdf2e093f52e06d3714f8 418 Pfam PF07690 Major Facilitator Superfamily 13 341 6.7E-16 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS18125 bd195ccb567fdf2e093f52e06d3714f8 418 Gene3D G3DSA:1.20.1250.20 199 401 9.4E-11 T 28-03-2018 CU254_RS33660 fc14d290671b97b3a496b0bb35255e3e 304 Gene3D G3DSA:1.10.287.1080 74 202 2.3E-41 T 28-03-2018 CU254_RS33660 fc14d290671b97b3a496b0bb35255e3e 304 TIGRFAM TIGR00444 mazG: MazG family protein 85 230 9.2E-45 T 28-03-2018 IPR011551 NTP pyrophosphohydrolase MazG CU254_RS33660 fc14d290671b97b3a496b0bb35255e3e 304 SUPERFAMILY SSF101386 81 179 2.76E-23 T 28-03-2018 CU254_RS33660 fc14d290671b97b3a496b0bb35255e3e 304 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 101 176 8.4E-27 T 28-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core CU254_RS16570 07b58d92af93ff669eccf917422c4a7b 851 Pfam PF13671 AAA domain 11 139 9.0E-22 T 28-03-2018 CU254_RS16570 07b58d92af93ff669eccf917422c4a7b 851 Pfam PF00149 Calcineurin-like phosphoesterase 182 377 8.4E-11 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CU254_RS16570 07b58d92af93ff669eccf917422c4a7b 851 Gene3D G3DSA:3.40.50.300 25 146 4.6E-14 T 28-03-2018 CU254_RS16570 07b58d92af93ff669eccf917422c4a7b 851 Gene3D G3DSA:3.40.50.300 2 24 0.0042 T 28-03-2018 CU254_RS16570 07b58d92af93ff669eccf917422c4a7b 851 Pfam PF16542 PNKP adenylyltransferase domain, ligase domain 470 788 1.3E-148 T 28-03-2018 IPR032380 Polynucleotide kinase-phosphatase, ligase domain CU254_RS16570 07b58d92af93ff669eccf917422c4a7b 851 Gene3D G3DSA:3.60.21.10 170 425 1.2E-52 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CU254_RS16570 07b58d92af93ff669eccf917422c4a7b 851 TIGRFAM TIGR04075 bacter_Pnkp: polynucleotide kinase-phosphatase 3 851 0.0 T 28-03-2018 IPR024028 Polynucleotide kinase-phosphatase, bacterial CU254_RS16570 07b58d92af93ff669eccf917422c4a7b 851 Pfam PF16536 PNKP adenylyltransferase domain, C-terminal region 793 851 7.2E-32 T 28-03-2018 IPR032390 Polynucleotide kinase-phosphatase, C-terminal CU254_RS16570 07b58d92af93ff669eccf917422c4a7b 851 SUPERFAMILY SSF56091 518 758 1.76E-12 T 28-03-2018 CU254_RS16570 07b58d92af93ff669eccf917422c4a7b 851 SUPERFAMILY SSF52540 11 146 3.95E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS16570 07b58d92af93ff669eccf917422c4a7b 851 SUPERFAMILY SSF56300 174 420 2.59E-44 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CU254_RS30975 04505a20e1813af7f311515783aab263 214 SUPERFAMILY SSF48498 82 212 2.0E-16 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS30975 04505a20e1813af7f311515783aab263 214 SUPERFAMILY SSF46689 5 75 2.39E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS30975 04505a20e1813af7f311515783aab263 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 7.6E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS30975 04505a20e1813af7f311515783aab263 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 7.6E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS30975 04505a20e1813af7f311515783aab263 214 Gene3D G3DSA:1.10.10.60 1 37 3.2E-12 T 28-03-2018 CU254_RS30975 04505a20e1813af7f311515783aab263 214 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 83 212 1.5E-8 T 28-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 CU254_RS30975 04505a20e1813af7f311515783aab263 214 Gene3D G3DSA:1.10.357.10 79 213 2.3E-22 T 28-03-2018 CU254_RS30975 04505a20e1813af7f311515783aab263 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 60 1.8E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS30975 04505a20e1813af7f311515783aab263 214 Gene3D G3DSA:1.10.260.40 38 78 1.7E-9 T 28-03-2018 CU254_RS16115 0ef8a43e6c694045320c0646e4f539ef 416 Pfam PF01548 Transposase 19 170 4.0E-36 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CU254_RS16115 0ef8a43e6c694045320c0646e4f539ef 416 Pfam PF02371 Transposase IS116/IS110/IS902 family 278 362 2.8E-17 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CU254_RS31995 d3e6795b7f94584d4cec84895f180412 351 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 239 258 - T 28-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 CU254_RS31995 d3e6795b7f94584d4cec84895f180412 351 SUPERFAMILY SSF53659 2 349 8.64E-118 T 28-03-2018 CU254_RS31995 d3e6795b7f94584d4cec84895f180412 351 Gene3D G3DSA:3.40.718.10 1 351 2.5E-122 T 28-03-2018 CU254_RS31995 d3e6795b7f94584d4cec84895f180412 351 TIGRFAM TIGR02089 TTC: tartrate dehydrogenase 2 349 1.0E-153 T 28-03-2018 IPR011829 Tartrate dehydrogenase GO:0016616|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.93|KEGG: 00650+1.1.1.83 CU254_RS31995 d3e6795b7f94584d4cec84895f180412 351 SMART SM01329 4 346 1.9E-176 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CU254_RS31995 d3e6795b7f94584d4cec84895f180412 351 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 5 343 1.1E-90 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CU254_RS05225 89dfccfe4adbc831dec81cb2449a6ff4 338 Gene3D G3DSA:3.30.300.50 12 88 1.3E-8 T 28-03-2018 IPR035070 Streptogrisin prodomain CU254_RS05225 89dfccfe4adbc831dec81cb2449a6ff4 338 PIRSF PIRSF001134 2 338 4.5E-59 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CU254_RS05225 89dfccfe4adbc831dec81cb2449a6ff4 338 Pfam PF02983 Alpha-lytic protease prodomain 92 145 2.7E-9 T 28-03-2018 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 CU254_RS05225 89dfccfe4adbc831dec81cb2449a6ff4 338 Gene3D G3DSA:3.30.300.50 89 158 7.2E-14 T 28-03-2018 IPR035070 Streptogrisin prodomain CU254_RS05225 89dfccfe4adbc831dec81cb2449a6ff4 338 Gene3D G3DSA:2.40.10.10 164 298 3.8E-13 T 28-03-2018 CU254_RS05225 89dfccfe4adbc831dec81cb2449a6ff4 338 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 190 204 1.1E-21 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CU254_RS05225 89dfccfe4adbc831dec81cb2449a6ff4 338 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 308 322 1.1E-21 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CU254_RS05225 89dfccfe4adbc831dec81cb2449a6ff4 338 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 244 264 1.1E-21 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CU254_RS05225 89dfccfe4adbc831dec81cb2449a6ff4 338 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 265 282 1.1E-21 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CU254_RS05225 89dfccfe4adbc831dec81cb2449a6ff4 338 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 284 307 1.1E-21 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CU254_RS05225 89dfccfe4adbc831dec81cb2449a6ff4 338 SUPERFAMILY SSF50494 168 324 2.05E-17 T 28-03-2018 IPR009003 Peptidase S1, PA clan CU254_RS42640 36b9b62936efa0e012b432a10ae5ff17 132 Gene3D G3DSA:2.30.30.30 2 57 6.6E-4 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 CU254_RS01790 bf68fe0fc6b84703e186d50170746539 393 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 16 300 2.6E-67 T 28-03-2018 IPR005693 Virulence factor Mce protein CU254_RS01790 bf68fe0fc6b84703e186d50170746539 393 Pfam PF02470 MlaD protein 38 111 1.7E-13 T 28-03-2018 IPR003399 Mce/MlaD CU254_RS01790 bf68fe0fc6b84703e186d50170746539 393 Gene3D G3DSA:1.20.5.50 218 293 0.022 T 28-03-2018 CU254_RS01790 bf68fe0fc6b84703e186d50170746539 393 Gene3D G3DSA:1.20.5.50 135 217 0.15 T 28-03-2018 CU254_RS09170 995afa87d07eee014778c1a6f221c6ff 441 PIRSF PIRSF000099 1 438 1.2E-153 T 28-03-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CU254_RS09170 995afa87d07eee014778c1a6f221c6ff 441 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 237 269 - T 28-03-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 CU254_RS09170 995afa87d07eee014778c1a6f221c6ff 441 Gene3D G3DSA:3.40.50.1980 28 233 1.1E-81 T 28-03-2018 CU254_RS09170 995afa87d07eee014778c1a6f221c6ff 441 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 35 435 1.3E-143 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CU254_RS09170 995afa87d07eee014778c1a6f221c6ff 441 Gene3D G3DSA:3.40.50.1980 234 380 6.4E-60 T 28-03-2018 CU254_RS09170 995afa87d07eee014778c1a6f221c6ff 441 Pfam PF00815 Histidinol dehydrogenase 22 436 1.4E-157 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CU254_RS09170 995afa87d07eee014778c1a6f221c6ff 441 SUPERFAMILY SSF53720 25 436 9.22E-72 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CU254_RS09170 995afa87d07eee014778c1a6f221c6ff 441 PRINTS PR00083 Histidinol dehydrogenase signature 208 233 1.6E-88 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CU254_RS09170 995afa87d07eee014778c1a6f221c6ff 441 PRINTS PR00083 Histidinol dehydrogenase signature 259 278 1.6E-88 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CU254_RS09170 995afa87d07eee014778c1a6f221c6ff 441 PRINTS PR00083 Histidinol dehydrogenase signature 370 388 1.6E-88 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CU254_RS09170 995afa87d07eee014778c1a6f221c6ff 441 PRINTS PR00083 Histidinol dehydrogenase signature 237 258 1.6E-88 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CU254_RS09170 995afa87d07eee014778c1a6f221c6ff 441 PRINTS PR00083 Histidinol dehydrogenase signature 329 354 1.6E-88 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CU254_RS09170 995afa87d07eee014778c1a6f221c6ff 441 PRINTS PR00083 Histidinol dehydrogenase signature 173 199 1.6E-88 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CU254_RS09170 995afa87d07eee014778c1a6f221c6ff 441 PRINTS PR00083 Histidinol dehydrogenase signature 136 162 1.6E-88 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CU254_RS09170 995afa87d07eee014778c1a6f221c6ff 441 PRINTS PR00083 Histidinol dehydrogenase signature 35 59 1.6E-88 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CU254_RS09170 995afa87d07eee014778c1a6f221c6ff 441 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 7 436 39.31 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CU254_RS37185 2aa04570fc6e9047139ee862785398de 279 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 17 32 - T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CU254_RS37185 2aa04570fc6e9047139ee862785398de 279 SUPERFAMILY SSF51717 12 272 2.35E-65 T 28-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CU254_RS37185 2aa04570fc6e9047139ee862785398de 279 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 18 270 1.7E-69 T 28-03-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 CU254_RS37185 2aa04570fc6e9047139ee862785398de 279 Pfam PF00809 Pterin binding enzyme 19 256 1.8E-57 T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CU254_RS37185 2aa04570fc6e9047139ee862785398de 279 Gene3D G3DSA:3.20.20.20 5 278 1.5E-71 T 28-03-2018 CU254_RS22790 7130b182dc32c3e30316e3c696847e4c 301 SUPERFAMILY SSF52540 2 231 3.12E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS22790 7130b182dc32c3e30316e3c696847e4c 301 Pfam PF00005 ABC transporter 20 157 5.6E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS22790 7130b182dc32c3e30316e3c696847e4c 301 Gene3D G3DSA:3.40.50.300 1 253 5.5E-64 T 28-03-2018 CU254_RS22790 7130b182dc32c3e30316e3c696847e4c 301 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS22790 7130b182dc32c3e30316e3c696847e4c 301 SMART SM00382 28 214 8.2E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS27550 86dbbecba2db1ee29949e721ea6e398c 67 PIRSF PIRSF002599 1 67 1.9E-25 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 CU254_RS27550 86dbbecba2db1ee29949e721ea6e398c 67 Gene3D G3DSA:2.40.50.140 1 67 6.5E-31 T 28-03-2018 CU254_RS27550 86dbbecba2db1ee29949e721ea6e398c 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 3.3E-32 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CU254_RS27550 86dbbecba2db1ee29949e721ea6e398c 67 SMART SM00357 3 67 1.3E-31 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 CU254_RS27550 86dbbecba2db1ee29949e721ea6e398c 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 28-03-2018 IPR019844 Cold-shock conserved site CU254_RS27550 86dbbecba2db1ee29949e721ea6e398c 67 PRINTS PR00050 Cold shock protein signature 25 34 3.3E-17 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CU254_RS27550 86dbbecba2db1ee29949e721ea6e398c 67 PRINTS PR00050 Cold shock protein signature 40 58 3.3E-17 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CU254_RS27550 86dbbecba2db1ee29949e721ea6e398c 67 PRINTS PR00050 Cold shock protein signature 4 19 3.3E-17 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CU254_RS27550 86dbbecba2db1ee29949e721ea6e398c 67 SUPERFAMILY SSF50249 1 66 5.57E-26 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CU254_RS26335 b02d4d9bd534a6d15e07d48c4740654f 201 SUPERFAMILY SSF52172 2 129 3.42E-32 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS26335 b02d4d9bd534a6d15e07d48c4740654f 201 Pfam PF00072 Response regulator receiver domain 4 116 3.4E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS26335 b02d4d9bd534a6d15e07d48c4740654f 201 SMART SM00448 2 115 3.2E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS26335 b02d4d9bd534a6d15e07d48c4740654f 201 Gene3D G3DSA:1.10.10.10 127 201 4.6E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS26335 b02d4d9bd534a6d15e07d48c4740654f 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 183 1.8E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS26335 b02d4d9bd534a6d15e07d48c4740654f 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 171 1.8E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS26335 b02d4d9bd534a6d15e07d48c4740654f 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 141 155 1.8E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS26335 b02d4d9bd534a6d15e07d48c4740654f 201 ProSitePatterns PS00622 LuxR-type HTH domain signature. 155 182 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS26335 b02d4d9bd534a6d15e07d48c4740654f 201 SMART SM00421 138 195 1.7E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS26335 b02d4d9bd534a6d15e07d48c4740654f 201 SUPERFAMILY SSF46894 131 201 2.48E-16 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS26335 b02d4d9bd534a6d15e07d48c4740654f 201 Gene3D G3DSA:3.40.50.2300 1 126 6.0E-37 T 28-03-2018 CU254_RS26335 b02d4d9bd534a6d15e07d48c4740654f 201 Pfam PF00196 Bacterial regulatory proteins, luxR family 140 194 6.0E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS06625 9bc832331ee992c254d4071cab9bce2b 315 Gene3D G3DSA:3.90.245.10 1 313 8.5E-98 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CU254_RS06625 9bc832331ee992c254d4071cab9bce2b 315 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 4 299 8.6E-83 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CU254_RS06625 9bc832331ee992c254d4071cab9bce2b 315 SUPERFAMILY SSF53590 4 311 2.22E-86 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CU254_RS32940 b4a7f8b31246a98a1c3d47e260b8ac27 166 Hamap MF_00105 Transcription elongation factor GreA [greA]. 8 161 28.276 T 28-03-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 CU254_RS32940 b4a7f8b31246a98a1c3d47e260b8ac27 166 Gene3D G3DSA:1.10.287.180 9 80 1.2E-24 T 28-03-2018 CU254_RS32940 b4a7f8b31246a98a1c3d47e260b8ac27 166 Gene3D G3DSA:3.10.50.30 81 166 3.0E-17 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CU254_RS32940 b4a7f8b31246a98a1c3d47e260b8ac27 166 Pfam PF03449 Transcription elongation factor, N-terminal 11 79 2.5E-24 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CU254_RS32940 b4a7f8b31246a98a1c3d47e260b8ac27 166 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 23 53 - T 28-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 CU254_RS32940 b4a7f8b31246a98a1c3d47e260b8ac27 166 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 86 159 2.0E-14 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CU254_RS32940 b4a7f8b31246a98a1c3d47e260b8ac27 166 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 125 141 - T 28-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 CU254_RS32940 b4a7f8b31246a98a1c3d47e260b8ac27 166 SUPERFAMILY SSF46557 10 81 5.89E-22 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CU254_RS32940 b4a7f8b31246a98a1c3d47e260b8ac27 166 SUPERFAMILY SSF54534 85 160 7.36E-12 T 28-03-2018 CU254_RS32940 b4a7f8b31246a98a1c3d47e260b8ac27 166 PIRSF PIRSF006092 4 163 5.1E-33 T 28-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 CU254_RS20330 50bc16efc6601c98adff299247406ccc 364 SMART SM00833 252 345 1.4E-30 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CU254_RS20330 50bc16efc6601c98adff299247406ccc 364 Gene3D G3DSA:3.40.50.300 1 225 8.5E-53 T 28-03-2018 CU254_RS20330 50bc16efc6601c98adff299247406ccc 364 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 252 345 8.8E-21 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CU254_RS20330 50bc16efc6601c98adff299247406ccc 364 Gene3D G3DSA:3.30.1220.10 236 346 3.8E-28 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CU254_RS20330 50bc16efc6601c98adff299247406ccc 364 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 4 206 8.1E-58 T 28-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CU254_RS20330 50bc16efc6601c98adff299247406ccc 364 SUPERFAMILY SSF52540 3 314 1.95E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS25935 c57ac7d9a4440572dd41094c5f52504f 1207 SUPERFAMILY SSF50370 681 804 2.16E-18 T 28-03-2018 IPR000772 Ricin B, lectin domain CU254_RS25935 c57ac7d9a4440572dd41094c5f52504f 1207 SUPERFAMILY SSF50494 135 291 5.56E-15 T 28-03-2018 IPR009003 Peptidase S1, PA clan CU254_RS25935 c57ac7d9a4440572dd41094c5f52504f 1207 SUPERFAMILY SSF50494 350 376 5.56E-15 T 28-03-2018 IPR009003 Peptidase S1, PA clan CU254_RS25935 c57ac7d9a4440572dd41094c5f52504f 1207 Gene3D G3DSA:2.40.10.10 68 214 1.9E-9 T 28-03-2018 CU254_RS25935 c57ac7d9a4440572dd41094c5f52504f 1207 SUPERFAMILY SSF50370 980 1104 1.76E-18 T 28-03-2018 IPR000772 Ricin B, lectin domain CU254_RS25935 c57ac7d9a4440572dd41094c5f52504f 1207 Gene3D G3DSA:2.80.10.50 964 1106 4.1E-21 T 28-03-2018 CU254_RS25935 c57ac7d9a4440572dd41094c5f52504f 1207 Gene3D G3DSA:2.80.10.50 814 956 9.6E-21 T 28-03-2018 CU254_RS25935 c57ac7d9a4440572dd41094c5f52504f 1207 Gene3D G3DSA:2.80.10.50 742 805 3.1E-8 T 28-03-2018 CU254_RS25935 c57ac7d9a4440572dd41094c5f52504f 1207 SMART SM00458 666 804 3.0E-6 T 28-03-2018 IPR000772 Ricin B, lectin domain CU254_RS25935 c57ac7d9a4440572dd41094c5f52504f 1207 SMART SM00458 815 954 3.9E-6 T 28-03-2018 IPR000772 Ricin B, lectin domain CU254_RS25935 c57ac7d9a4440572dd41094c5f52504f 1207 SMART SM00458 965 1104 3.8E-7 T 28-03-2018 IPR000772 Ricin B, lectin domain CU254_RS25935 c57ac7d9a4440572dd41094c5f52504f 1207 Pfam PF00089 Trypsin 136 264 8.7E-9 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CU254_RS25935 c57ac7d9a4440572dd41094c5f52504f 1207 SUPERFAMILY SSF50370 822 954 1.13E-18 T 28-03-2018 IPR000772 Ricin B, lectin domain CU254_RS25935 c57ac7d9a4440572dd41094c5f52504f 1207 Pfam PF00652 Ricin-type beta-trefoil lectin domain 825 951 3.1E-8 T 28-03-2018 IPR000772 Ricin B, lectin domain CU254_RS25935 c57ac7d9a4440572dd41094c5f52504f 1207 Pfam PF00652 Ricin-type beta-trefoil lectin domain 974 1101 2.2E-8 T 28-03-2018 IPR000772 Ricin B, lectin domain CU254_RS25935 c57ac7d9a4440572dd41094c5f52504f 1207 Pfam PF00652 Ricin-type beta-trefoil lectin domain 674 801 2.3E-8 T 28-03-2018 IPR000772 Ricin B, lectin domain CU254_RS25935 c57ac7d9a4440572dd41094c5f52504f 1207 Gene3D G3DSA:2.80.10.50 600 741 2.1E-11 T 28-03-2018 CU254_RS25935 c57ac7d9a4440572dd41094c5f52504f 1207 SMART SM00020 123 376 0.0035 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CU254_RS25935 c57ac7d9a4440572dd41094c5f52504f 1207 Gene3D G3DSA:2.40.10.10 215 392 8.8E-6 T 28-03-2018 CU254_RS08850 6afd34648510d12dc810ef011a67d48c 644 Gene3D G3DSA:3.60.20.10 1 230 5.9E-46 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CU254_RS08850 6afd34648510d12dc810ef011a67d48c 644 Pfam PF00733 Asparagine synthase 253 623 2.0E-96 T 28-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 CU254_RS08850 6afd34648510d12dc810ef011a67d48c 644 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 561 2.7E-133 T 28-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 CU254_RS08850 6afd34648510d12dc810ef011a67d48c 644 PIRSF PIRSF001589 1 637 3.0E-163 T 28-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 CU254_RS08850 6afd34648510d12dc810ef011a67d48c 644 SUPERFAMILY SSF52402 245 394 4.19E-80 T 28-03-2018 CU254_RS08850 6afd34648510d12dc810ef011a67d48c 644 SUPERFAMILY SSF52402 481 619 4.19E-80 T 28-03-2018 CU254_RS08850 6afd34648510d12dc810ef011a67d48c 644 SUPERFAMILY SSF56235 2 231 1.8E-50 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CU254_RS08850 6afd34648510d12dc810ef011a67d48c 644 Gene3D G3DSA:3.40.50.620 231 628 8.8E-78 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS08850 6afd34648510d12dc810ef011a67d48c 644 Pfam PF13537 Glutamine amidotransferase domain 50 172 3.4E-36 T 28-03-2018 IPR017932 Glutamine amidotransferase type 2 domain CU254_RS11500 4eb274912c0149b78b05f152d5f5a85e 105 SUPERFAMILY SSF46946 55 103 2.56E-6 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CU254_RS11500 4eb274912c0149b78b05f152d5f5a85e 105 PIRSF PIRSF002134 38 104 1.4E-4 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS11500 4eb274912c0149b78b05f152d5f5a85e 105 Gene3D G3DSA:1.10.8.50 47 105 1.2E-5 T 28-03-2018 CU254_RS03295 7d898e5d684b7b297d510cebbd896ab2 257 Pfam PF02525 Flavodoxin-like fold 25 214 2.1E-52 T 28-03-2018 IPR003680 Flavodoxin-like fold CU254_RS03295 7d898e5d684b7b297d510cebbd896ab2 257 Gene3D G3DSA:3.40.50.360 21 256 8.7E-58 T 28-03-2018 IPR029039 Flavoprotein-like domain CU254_RS03295 7d898e5d684b7b297d510cebbd896ab2 257 SUPERFAMILY SSF52218 25 255 6.29E-63 T 28-03-2018 IPR029039 Flavoprotein-like domain CU254_RS07510 0cf4e1e2dc0ca27d40a42f28c94786b4 280 Gene3D G3DSA:3.20.20.140 1 280 7.1E-40 T 28-03-2018 CU254_RS07510 0cf4e1e2dc0ca27d40a42f28c94786b4 280 SUPERFAMILY SSF51556 2 275 1.94E-64 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS07510 0cf4e1e2dc0ca27d40a42f28c94786b4 280 Pfam PF04909 Amidohydrolase 2 274 9.1E-37 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CU254_RS21825 092588edce2ee920a70dd834acf0fd0d 205 Gene3D G3DSA:3.50.30.40 3 178 2.8E-49 T 28-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CU254_RS21825 092588edce2ee920a70dd834acf0fd0d 205 SUPERFAMILY SSF89562 7 168 2.75E-40 T 28-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CU254_RS21825 092588edce2ee920a70dd834acf0fd0d 205 Pfam PF03737 Aldolase/RraA 10 158 2.5E-38 T 28-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CU254_RS09205 e9b52032a45d340661e01a85e9ed7100 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 7.7E-17 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS09205 e9b52032a45d340661e01a85e9ed7100 193 Gene3D G3DSA:1.10.260.40 36 90 2.6E-14 T 28-03-2018 CU254_RS09205 e9b52032a45d340661e01a85e9ed7100 193 SUPERFAMILY SSF46689 5 77 1.18E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS09205 e9b52032a45d340661e01a85e9ed7100 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 1.6E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS09205 e9b52032a45d340661e01a85e9ed7100 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 1.6E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS09205 e9b52032a45d340661e01a85e9ed7100 193 Gene3D G3DSA:1.10.10.60 2 35 5.4E-17 T 28-03-2018 CU254_RS09205 e9b52032a45d340661e01a85e9ed7100 193 ProSitePatterns PS01081 TetR-type HTH domain signature. 26 56 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CU254_RS23805 b01822816e1008d3be75e49cfcfe9b84 348 SUPERFAMILY SSF51679 22 332 3.53E-68 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS23805 b01822816e1008d3be75e49cfcfe9b84 348 Gene3D G3DSA:3.20.20.30 1 340 3.1E-71 T 28-03-2018 CU254_RS23805 b01822816e1008d3be75e49cfcfe9b84 348 Pfam PF00296 Luciferase-like monooxygenase 3 303 3.3E-62 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS07430 007011402d5c5c6a8efb3d13dea4c56f 269 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS07430 007011402d5c5c6a8efb3d13dea4c56f 269 Pfam PF00005 ABC transporter 32 173 1.5E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS07430 007011402d5c5c6a8efb3d13dea4c56f 269 Gene3D G3DSA:3.40.50.300 2 245 5.5E-58 T 28-03-2018 CU254_RS07430 007011402d5c5c6a8efb3d13dea4c56f 269 SMART SM00382 34 231 1.5E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS07430 007011402d5c5c6a8efb3d13dea4c56f 269 SUPERFAMILY SSF52540 6 240 4.2E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS35580 7a915fc5140ba02c49d60cceae225851 242 Pfam PF00691 OmpA family 138 232 1.0E-9 T 28-03-2018 IPR006665 OmpA-like domain CU254_RS35580 7a915fc5140ba02c49d60cceae225851 242 SUPERFAMILY SSF103088 135 239 1.2E-12 T 28-03-2018 IPR006665 OmpA-like domain CU254_RS35580 7a915fc5140ba02c49d60cceae225851 242 Gene3D G3DSA:3.30.1330.60 87 242 1.0E-16 T 28-03-2018 IPR006665 OmpA-like domain CU254_RS24725 79965ae2f0c8ba2527c5339efbedac3f 281 Pfam PF04012 PspA/IM30 family 3 241 1.1E-50 T 28-03-2018 IPR007157 PspA/IM30 CU254_RS32230 173ffc0fc489de50a58042e4af586ffa 1229 Pfam PF00676 Dehydrogenase E1 component 503 825 5.2E-60 T 28-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 CU254_RS32230 173ffc0fc489de50a58042e4af586ffa 1229 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 10 43 9.1E-13 T 28-03-2018 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CU254_RS32230 173ffc0fc489de50a58042e4af586ffa 1229 SUPERFAMILY SSF52518 875 1088 6.08E-44 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS32230 173ffc0fc489de50a58042e4af586ffa 1229 Pfam PF02779 Transketolase, pyrimidine binding domain 888 1081 1.8E-51 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CU254_RS32230 173ffc0fc489de50a58042e4af586ffa 1229 SUPERFAMILY SSF52518 416 830 1.77E-84 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS32230 173ffc0fc489de50a58042e4af586ffa 1229 Gene3D G3DSA:3.40.50.970 884 1094 3.2E-50 T 28-03-2018 CU254_RS32230 173ffc0fc489de50a58042e4af586ffa 1229 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 119 351 1.7E-53 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CU254_RS32230 173ffc0fc489de50a58042e4af586ffa 1229 SMART SM00861 888 1081 6.8E-50 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CU254_RS32230 173ffc0fc489de50a58042e4af586ffa 1229 Gene3D G3DSA:3.40.50.970 462 823 1.6E-92 T 28-03-2018 CU254_RS32230 173ffc0fc489de50a58042e4af586ffa 1229 SUPERFAMILY SSF52777 107 351 1.38E-53 T 28-03-2018 CU254_RS32230 173ffc0fc489de50a58042e4af586ffa 1229 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 1085 1228 1.9E-43 T 28-03-2018 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CU254_RS32230 173ffc0fc489de50a58042e4af586ffa 1229 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 385 1227 5.0E-298 T 28-03-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CU254_RS32230 173ffc0fc489de50a58042e4af586ffa 1229 Gene3D G3DSA:3.30.559.10 101 352 2.1E-51 T 28-03-2018 CU254_RS32230 173ffc0fc489de50a58042e4af586ffa 1229 Gene3D G3DSA:1.10.287.1150 379 461 1.5E-23 T 28-03-2018 CU254_RS32230 173ffc0fc489de50a58042e4af586ffa 1229 PIRSF PIRSF000157 2 1229 0.0 T 28-03-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CU254_RS37430 c6115bf81a10368f18ab036d3e7f6da5 258 Gene3D G3DSA:3.40.50.300 1 256 1.2E-58 T 28-03-2018 CU254_RS37430 c6115bf81a10368f18ab036d3e7f6da5 258 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS37430 c6115bf81a10368f18ab036d3e7f6da5 258 SMART SM00382 29 229 6.2E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS37430 c6115bf81a10368f18ab036d3e7f6da5 258 SUPERFAMILY SSF52540 5 245 4.02E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS37430 c6115bf81a10368f18ab036d3e7f6da5 258 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 5 258 1.8E-115 T 28-03-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 CU254_RS37430 c6115bf81a10368f18ab036d3e7f6da5 258 Pfam PF00005 ABC transporter 21 176 1.6E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS27185 c90ff39446335a316b44cf1ba8865faa 414 SUPERFAMILY SSF50249 10 95 2.1E-17 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CU254_RS27185 c90ff39446335a316b44cf1ba8865faa 414 SUPERFAMILY SSF55681 92 413 1.13E-72 T 28-03-2018 CU254_RS27185 c90ff39446335a316b44cf1ba8865faa 414 Pfam PF00152 tRNA synthetases class II (D, K and N) 111 408 1.5E-64 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CU254_RS27185 c90ff39446335a316b44cf1ba8865faa 414 Gene3D G3DSA:2.40.50.140 4 94 1.8E-13 T 28-03-2018 CU254_RS27185 c90ff39446335a316b44cf1ba8865faa 414 Hamap MF_02075 Aspartate--tRNA(Asp) ligase [aspS]. 2 414 35.533 T 28-03-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CU254_RS27185 c90ff39446335a316b44cf1ba8865faa 414 Pfam PF01336 OB-fold nucleic acid binding domain 18 86 1.4E-10 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CU254_RS27185 c90ff39446335a316b44cf1ba8865faa 414 Gene3D G3DSA:3.30.930.10 101 402 5.6E-68 T 28-03-2018 CU254_RS27185 c90ff39446335a316b44cf1ba8865faa 414 PRINTS PR01042 Aspartyl-tRNA synthetase signature 369 383 1.6E-14 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CU254_RS27185 c90ff39446335a316b44cf1ba8865faa 414 PRINTS PR01042 Aspartyl-tRNA synthetase signature 193 206 1.6E-14 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CU254_RS27185 c90ff39446335a316b44cf1ba8865faa 414 PRINTS PR01042 Aspartyl-tRNA synthetase signature 177 189 1.6E-14 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CU254_RS09980 f09af4c94580a1074c554d56cd9d87b4 116 SMART SM00422 1 69 4.0E-20 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS09980 f09af4c94580a1074c554d56cd9d87b4 116 Gene3D G3DSA:1.10.1660.10 1 53 2.1E-23 T 28-03-2018 CU254_RS09980 f09af4c94580a1074c554d56cd9d87b4 116 SUPERFAMILY SSF46955 1 111 1.32E-26 T 28-03-2018 IPR009061 Putative DNA-binding domain CU254_RS09980 f09af4c94580a1074c554d56cd9d87b4 116 Pfam PF13411 MerR HTH family regulatory protein 1 65 1.2E-18 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS09980 f09af4c94580a1074c554d56cd9d87b4 116 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 1.3E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS09980 f09af4c94580a1074c554d56cd9d87b4 116 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 1.3E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS09980 f09af4c94580a1074c554d56cd9d87b4 116 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 1.3E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS09980 f09af4c94580a1074c554d56cd9d87b4 116 Gene3D G3DSA:1.10.1660.10 54 116 5.2E-12 T 28-03-2018 CU254_RS13440 96e3605e8f003092304a4903a233bd46 608 Gene3D G3DSA:2.60.120.200 393 603 1.9E-29 T 28-03-2018 CU254_RS13440 96e3605e8f003092304a4903a233bd46 608 Gene3D G3DSA:2.120.10.10 18 392 3.4E-76 T 28-03-2018 CU254_RS13440 96e3605e8f003092304a4903a233bd46 608 Pfam PF13088 BNR repeat-like domain 56 361 5.6E-33 T 28-03-2018 IPR011040 Sialidases KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 CU254_RS13440 96e3605e8f003092304a4903a233bd46 608 SUPERFAMILY SSF50939 33 396 4.49E-88 T 28-03-2018 IPR011040 Sialidases KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 CU254_RS13440 96e3605e8f003092304a4903a233bd46 608 SMART SM00282 447 581 7.0E-4 T 28-03-2018 IPR001791 Laminin G domain CU254_RS13440 96e3605e8f003092304a4903a233bd46 608 SMART SM00560 451 586 2.3E-7 T 28-03-2018 IPR006558 LamG-like jellyroll fold CU254_RS13440 96e3605e8f003092304a4903a233bd46 608 SUPERFAMILY SSF49899 404 591 6.43E-28 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CU254_RS13440 96e3605e8f003092304a4903a233bd46 608 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 438 585 1.8E-21 T 28-03-2018 CU254_RS13335 3d278a6cf05910d5de2404466673d9b0 1201 Pfam PF02574 Homocysteine S-methyltransferase 14 312 6.4E-77 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CU254_RS13335 3d278a6cf05910d5de2404466673d9b0 1201 SUPERFAMILY SSF51717 343 617 1.31E-80 T 28-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CU254_RS13335 3d278a6cf05910d5de2404466673d9b0 1201 Gene3D G3DSA:3.20.20.330 1 324 2.2E-109 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CU254_RS13335 3d278a6cf05910d5de2404466673d9b0 1201 SUPERFAMILY SSF82282 2 386 1.31E-118 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CU254_RS13335 3d278a6cf05910d5de2404466673d9b0 1201 PIRSF PIRSF000381 1 1172 0.0 T 28-03-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CU254_RS13335 3d278a6cf05910d5de2404466673d9b0 1201 SUPERFAMILY SSF47644 636 723 4.05E-29 T 28-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CU254_RS13335 3d278a6cf05910d5de2404466673d9b0 1201 SMART SM01018 641 724 2.9E-45 T 28-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CU254_RS13335 3d278a6cf05910d5de2404466673d9b0 1201 Pfam PF02607 B12 binding domain 643 717 2.1E-26 T 28-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CU254_RS13335 3d278a6cf05910d5de2404466673d9b0 1201 Gene3D G3DSA:3.40.50.280 736 888 3.7E-50 T 28-03-2018 CU254_RS13335 3d278a6cf05910d5de2404466673d9b0 1201 SUPERFAMILY SSF52242 737 887 1.96E-42 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CU254_RS13335 3d278a6cf05910d5de2404466673d9b0 1201 Gene3D G3DSA:3.10.196.10 946 1201 2.7E-82 T 28-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CU254_RS13335 3d278a6cf05910d5de2404466673d9b0 1201 SUPERFAMILY SSF56507 895 1201 5.62E-101 T 28-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CU254_RS13335 3d278a6cf05910d5de2404466673d9b0 1201 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 928 1185 3.0E-98 T 28-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CU254_RS13335 3d278a6cf05910d5de2404466673d9b0 1201 Gene3D G3DSA:3.20.20.20 332 630 2.1E-66 T 28-03-2018 CU254_RS13335 3d278a6cf05910d5de2404466673d9b0 1201 Pfam PF00809 Pterin binding enzyme 347 585 1.1E-49 T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CU254_RS13335 3d278a6cf05910d5de2404466673d9b0 1201 Gene3D G3DSA:1.10.1240.10 631 724 1.1E-36 T 28-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CU254_RS13335 3d278a6cf05910d5de2404466673d9b0 1201 TIGRFAM TIGR02082 metH: methionine synthase 9 1169 0.0 T 28-03-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CU254_RS13335 3d278a6cf05910d5de2404466673d9b0 1201 Pfam PF02310 B12 binding domain 741 834 1.0E-18 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CU254_RS03685 521f30480468df713bfa9c751b0273c7 499 SUPERFAMILY SSF90123 8 282 1.7E-31 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CU254_RS03685 521f30480468df713bfa9c751b0273c7 499 Gene3D G3DSA:1.20.1560.10 6 283 5.5E-24 T 28-03-2018 CU254_RS03685 521f30480468df713bfa9c751b0273c7 499 SUPERFAMILY SSF52540 297 497 7.17E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS03685 521f30480468df713bfa9c751b0273c7 499 Gene3D G3DSA:3.40.50.300 286 499 9.1E-51 T 28-03-2018 CU254_RS03685 521f30480468df713bfa9c751b0273c7 499 ProSitePatterns PS00211 ABC transporters family signature. 422 436 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS03685 521f30480468df713bfa9c751b0273c7 499 Pfam PF00664 ABC transporter transmembrane region 84 250 2.5E-12 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CU254_RS03685 521f30480468df713bfa9c751b0273c7 499 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 10 493 1.1E-141 T 28-03-2018 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 CU254_RS03685 521f30480468df713bfa9c751b0273c7 499 Pfam PF00005 ABC transporter 317 451 2.4E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS03685 521f30480468df713bfa9c751b0273c7 499 SMART SM00382 326 498 3.2E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS40095 d8c2058adbc8ea9ba1e8c62f2e2e200b 106 SUPERFAMILY SSF101386 2 102 1.64E-30 T 28-03-2018 CU254_RS40095 d8c2058adbc8ea9ba1e8c62f2e2e200b 106 PIRSF PIRSF029826 1 105 2.6E-39 T 28-03-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 CU254_RS40095 d8c2058adbc8ea9ba1e8c62f2e2e200b 106 Pfam PF12643 MazG-like family 32 101 1.8E-9 T 28-03-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 CU254_RS40095 d8c2058adbc8ea9ba1e8c62f2e2e200b 106 Gene3D G3DSA:1.10.4010.10 1 106 1.1E-24 T 28-03-2018 CU254_RS36000 ff1ac1499f02137498fe111e79ddd9b3 461 Gene3D G3DSA:3.40.50.620 1 302 1.5E-83 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS36000 ff1ac1499f02137498fe111e79ddd9b3 461 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 6.8E-26 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CU254_RS36000 ff1ac1499f02137498fe111e79ddd9b3 461 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 220 241 6.8E-26 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CU254_RS36000 ff1ac1499f02137498fe111e79ddd9b3 461 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 6.8E-26 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CU254_RS36000 ff1ac1499f02137498fe111e79ddd9b3 461 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 189 207 6.8E-26 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CU254_RS36000 ff1ac1499f02137498fe111e79ddd9b3 461 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 3 457 7.6E-129 T 28-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 CU254_RS36000 ff1ac1499f02137498fe111e79ddd9b3 461 Gene3D G3DSA:1.20.120.640 303 389 1.2E-17 T 28-03-2018 CU254_RS36000 ff1ac1499f02137498fe111e79ddd9b3 461 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 17 309 7.8E-117 T 28-03-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 CU254_RS36000 ff1ac1499f02137498fe111e79ddd9b3 461 SMART SM00840 337 399 5.5E-14 T 28-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 CU254_RS36000 ff1ac1499f02137498fe111e79ddd9b3 461 SUPERFAMILY SSF52374 4 308 1.29E-86 T 28-03-2018 CU254_RS36000 ff1ac1499f02137498fe111e79ddd9b3 461 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 459 35.069 T 28-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 CU254_RS36000 ff1ac1499f02137498fe111e79ddd9b3 461 SUPERFAMILY SSF47323 323 458 6.8E-33 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CU254_RS36000 ff1ac1499f02137498fe111e79ddd9b3 461 Pfam PF09190 DALR domain 337 390 1.5E-10 T 28-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 CU254_RS10115 fc2099c12b59fc135b8c961830cbae00 144 Gene3D G3DSA:3.10.180.10 5 143 5.4E-18 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS10115 fc2099c12b59fc135b8c961830cbae00 144 SUPERFAMILY SSF54593 7 143 2.91E-7 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS12010 fd655a1d1a4f0202a60695b815be47d5 263 TIGRFAM TIGR03084 TIGR03084: TIGR03084 family protein 7 257 9.3E-110 T 28-03-2018 IPR017518 Conserved hypothetical protein CHP03084 CU254_RS12010 fd655a1d1a4f0202a60695b815be47d5 263 Pfam PF08608 Wyosine base formation 184 235 4.7E-8 T 28-03-2018 IPR013917 tRNA wybutosine-synthesis MetaCyc: PWY-7285|MetaCyc: PWY-7286 CU254_RS12010 fd655a1d1a4f0202a60695b815be47d5 263 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 10 224 1.4E-52 T 28-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CU254_RS12010 fd655a1d1a4f0202a60695b815be47d5 263 Gene3D G3DSA:1.20.120.450 1 153 7.6E-30 T 28-03-2018 CU254_RS12010 fd655a1d1a4f0202a60695b815be47d5 263 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 11 147 1.9E-33 T 28-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CU254_RS12010 fd655a1d1a4f0202a60695b815be47d5 263 SUPERFAMILY SSF109854 1 153 1.53E-40 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CU254_RS14935 526eb61a51444b3555242a5132319115 216 SUPERFAMILY SSF52172 2 144 2.99E-21 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS14935 526eb61a51444b3555242a5132319115 216 Gene3D G3DSA:1.10.10.10 132 214 1.2E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS14935 526eb61a51444b3555242a5132319115 216 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 194 1.2E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS14935 526eb61a51444b3555242a5132319115 216 SMART SM00448 1 120 1.8E-12 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS14935 526eb61a51444b3555242a5132319115 216 Pfam PF00072 Response regulator receiver domain 4 108 2.5E-17 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS14935 526eb61a51444b3555242a5132319115 216 SUPERFAMILY SSF46894 135 194 1.26E-14 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS14935 526eb61a51444b3555242a5132319115 216 SMART SM00421 147 210 9.8E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS14935 526eb61a51444b3555242a5132319115 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 9.0E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS14935 526eb61a51444b3555242a5132319115 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 9.0E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS14935 526eb61a51444b3555242a5132319115 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 9.0E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS14935 526eb61a51444b3555242a5132319115 216 Gene3D G3DSA:3.40.50.2300 1 131 8.2E-28 T 28-03-2018 CU254_RS27865 4719782a404d60d4525221514a7220a1 206 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 7 200 2.6E-52 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 CU254_RS27865 4719782a404d60d4525221514a7220a1 206 SUPERFAMILY SSF55821 1 204 4.88E-59 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CU254_RS27865 4719782a404d60d4525221514a7220a1 206 Pfam PF01300 Telomere recombination 23 198 1.2E-41 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 CU254_RS27865 4719782a404d60d4525221514a7220a1 206 Gene3D G3DSA:3.90.870.10 1 205 2.8E-56 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CU254_RS36705 fb16ec09bdd997610a1592a0bd20d865 211 Pfam PF00857 Isochorismatase family 22 193 1.8E-39 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CU254_RS36705 fb16ec09bdd997610a1592a0bd20d865 211 PIRSF PIRSF001111 1 209 1.6E-94 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CU254_RS36705 fb16ec09bdd997610a1592a0bd20d865 211 PRINTS PR01398 Isochorismatase signature 70 89 9.0E-45 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CU254_RS36705 fb16ec09bdd997610a1592a0bd20d865 211 PRINTS PR01398 Isochorismatase signature 176 193 9.0E-45 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CU254_RS36705 fb16ec09bdd997610a1592a0bd20d865 211 PRINTS PR01398 Isochorismatase signature 102 124 9.0E-45 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CU254_RS36705 fb16ec09bdd997610a1592a0bd20d865 211 PRINTS PR01398 Isochorismatase signature 53 70 9.0E-45 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CU254_RS36705 fb16ec09bdd997610a1592a0bd20d865 211 PRINTS PR01398 Isochorismatase signature 158 176 9.0E-45 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CU254_RS36705 fb16ec09bdd997610a1592a0bd20d865 211 Gene3D G3DSA:3.40.50.850 1 201 4.1E-49 T 28-03-2018 CU254_RS36705 fb16ec09bdd997610a1592a0bd20d865 211 SUPERFAMILY SSF52499 2 200 1.7E-61 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CU254_RS14060 100e6fa4b620784c9c97812232ba660f 437 SUPERFAMILY SSF53187 102 424 1.75E-61 T 28-03-2018 CU254_RS14060 100e6fa4b620784c9c97812232ba660f 437 Pfam PF00246 Zinc carboxypeptidase 114 405 4.7E-48 T 28-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 CU254_RS14060 100e6fa4b620784c9c97812232ba660f 437 SMART SM00631 107 413 4.1E-36 T 28-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 CU254_RS14060 100e6fa4b620784c9c97812232ba660f 437 Gene3D G3DSA:3.40.630.10 102 435 2.5E-59 T 28-03-2018 CU254_RS15180 1492bb547530d874616e9e4dd305ade7 245 Gene3D G3DSA:3.40.50.1820 2 244 1.9E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS15180 1492bb547530d874616e9e4dd305ade7 245 Pfam PF12697 Alpha/beta hydrolase family 16 229 1.5E-13 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS15180 1492bb547530d874616e9e4dd305ade7 245 SUPERFAMILY SSF53474 3 230 1.25E-32 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS22305 e672b40b84b299122102dc8ecc21d518 310 Gene3D G3DSA:1.10.150.130 2 121 1.0E-21 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CU254_RS22305 e672b40b84b299122102dc8ecc21d518 310 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 12 98 2.8E-17 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CU254_RS22305 e672b40b84b299122102dc8ecc21d518 310 Gene3D G3DSA:1.10.443.10 122 302 1.2E-49 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CU254_RS22305 e672b40b84b299122102dc8ecc21d518 310 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 8 308 55.984 T 28-03-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 CU254_RS22305 e672b40b84b299122102dc8ecc21d518 310 SUPERFAMILY SSF56349 11 300 1.21E-56 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CU254_RS22305 e672b40b84b299122102dc8ecc21d518 310 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 14 308 1.1E-105 T 28-03-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 CU254_RS22305 e672b40b84b299122102dc8ecc21d518 310 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 10 308 55.559 T 28-03-2018 IPR023009 Tyrosine recombinase XerC/XerD CU254_RS22305 e672b40b84b299122102dc8ecc21d518 310 Pfam PF00589 Phage integrase family 125 292 8.3E-48 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CU254_RS38510 81b7ae7647cfe449ec7b9584277006f3 414 SUPERFAMILY SSF140459 30 161 7.32E-5 T 28-03-2018 CU254_RS34580 6a96e99f514263f795bee70789c9a88b 130 SUPERFAMILY SSF55298 3 129 2.2E-29 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CU254_RS34580 6a96e99f514263f795bee70789c9a88b 130 Gene3D G3DSA:3.30.1330.40 6 130 1.8E-28 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CU254_RS34580 6a96e99f514263f795bee70789c9a88b 130 Pfam PF01042 Endoribonuclease L-PSP 14 128 2.1E-19 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family CU254_RS29600 ee76e5030cc9290a1dc069b1ddb825f4 128 SUPERFAMILY SSF54427 2 126 1.76E-34 T 28-03-2018 IPR032710 NTF2-like domain CU254_RS29600 ee76e5030cc9290a1dc069b1ddb825f4 128 Pfam PF12680 SnoaL-like domain 8 113 8.2E-15 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CU254_RS29600 ee76e5030cc9290a1dc069b1ddb825f4 128 Gene3D G3DSA:3.10.450.50 2 128 8.7E-23 T 28-03-2018 CU254_RS41355 64e0c31f499d579c3cf18c65d4533691 403 SMART SM00530 26 81 9.4E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS41355 64e0c31f499d579c3cf18c65d4533691 403 Gene3D G3DSA:1.10.260.40 25 100 3.4E-14 T 28-03-2018 CU254_RS41355 64e0c31f499d579c3cf18c65d4533691 403 Gene3D G3DSA:1.25.40.10 292 368 0.0023 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS41355 64e0c31f499d579c3cf18c65d4533691 403 Gene3D G3DSA:1.25.40.10 108 265 0.029 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS41355 64e0c31f499d579c3cf18c65d4533691 403 SUPERFAMILY SSF47413 26 82 9.85E-12 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS41355 64e0c31f499d579c3cf18c65d4533691 403 Pfam PF01381 Helix-turn-helix 27 81 5.3E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS31670 8276f64bf3567463b84221d50c59eda0 200 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 10 182 2.1E-26 T 28-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CU254_RS31670 8276f64bf3567463b84221d50c59eda0 200 SUPERFAMILY SSF109854 7 119 7.94E-15 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CU254_RS31670 8276f64bf3567463b84221d50c59eda0 200 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 6 92 3.4E-9 T 28-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CU254_RS31670 8276f64bf3567463b84221d50c59eda0 200 Gene3D G3DSA:1.20.120.450 1 180 4.2E-17 T 28-03-2018 CU254_RS42480 8b95b34ad18428d7828d905ea511d68f 162 Gene3D G3DSA:1.10.260.40 2 76 1.1E-9 T 28-03-2018 CU254_RS42480 8b95b34ad18428d7828d905ea511d68f 162 Pfam PF13560 Helix-turn-helix domain 11 71 1.6E-6 T 28-03-2018 CU254_RS42480 8b95b34ad18428d7828d905ea511d68f 162 SUPERFAMILY SSF47413 6 72 2.2E-7 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS42480 8b95b34ad18428d7828d905ea511d68f 162 Gene3D G3DSA:1.10.260.40 87 153 0.15 T 28-03-2018 CU254_RS02955 bb44241b7b994eb2505b43c6d7f49e99 210 SUPERFAMILY SSF48498 86 194 1.05E-21 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS02955 bb44241b7b994eb2505b43c6d7f49e99 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 1.0E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS02955 bb44241b7b994eb2505b43c6d7f49e99 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 1.0E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS02955 bb44241b7b994eb2505b43c6d7f49e99 210 Gene3D G3DSA:1.10.357.10 8 202 9.5E-32 T 28-03-2018 CU254_RS02955 bb44241b7b994eb2505b43c6d7f49e99 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 65 9.8E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS02955 bb44241b7b994eb2505b43c6d7f49e99 210 SUPERFAMILY SSF46689 8 91 1.05E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS07100 a7bdd5d0352e30557ca3abc82a51280a 508 Pfam PF00144 Beta-lactamase 45 343 3.8E-59 T 28-03-2018 IPR001466 Beta-lactamase-related CU254_RS07100 a7bdd5d0352e30557ca3abc82a51280a 508 SUPERFAMILY SSF56601 4 353 2.51E-73 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CU254_RS07100 a7bdd5d0352e30557ca3abc82a51280a 508 Gene3D G3DSA:3.40.710.10 17 350 1.9E-70 T 28-03-2018 CU254_RS05080 24e1fbc9d9d2efb381e3647ecaa48ea0 829 SMART SM00560 689 821 1.3E-18 T 28-03-2018 IPR006558 LamG-like jellyroll fold CU254_RS05080 24e1fbc9d9d2efb381e3647ecaa48ea0 829 SUPERFAMILY SSF49303 233 322 7.77E-12 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 CU254_RS05080 24e1fbc9d9d2efb381e3647ecaa48ea0 829 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 672 824 8.4E-29 T 28-03-2018 CU254_RS05080 24e1fbc9d9d2efb381e3647ecaa48ea0 829 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 102 224 6.2E-15 T 28-03-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CU254_RS05080 24e1fbc9d9d2efb381e3647ecaa48ea0 829 Pfam PF00703 Glycosyl hydrolases family 2 247 321 4.8E-8 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 CU254_RS05080 24e1fbc9d9d2efb381e3647ecaa48ea0 829 Gene3D G3DSA:2.60.40.10 243 313 9.4E-14 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS05080 24e1fbc9d9d2efb381e3647ecaa48ea0 829 Gene3D G3DSA:3.20.20.80 314 560 3.9E-33 T 28-03-2018 CU254_RS05080 24e1fbc9d9d2efb381e3647ecaa48ea0 829 SUPERFAMILY SSF49785 58 229 9.72E-47 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS05080 24e1fbc9d9d2efb381e3647ecaa48ea0 829 SUPERFAMILY SSF49899 630 828 8.31E-39 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CU254_RS05080 24e1fbc9d9d2efb381e3647ecaa48ea0 829 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 368 478 8.7E-5 T 28-03-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 CU254_RS05080 24e1fbc9d9d2efb381e3647ecaa48ea0 829 Gene3D G3DSA:2.60.120.260 32 242 1.9E-42 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS05080 24e1fbc9d9d2efb381e3647ecaa48ea0 829 SUPERFAMILY SSF51445 318 602 8.57E-62 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS05080 24e1fbc9d9d2efb381e3647ecaa48ea0 829 Gene3D G3DSA:2.60.120.200 621 829 4.5E-45 T 28-03-2018 CU254_RS28295 ed96e85b25cd80bf12cacd4be070b5dc 468 Gene3D G3DSA:3.20.20.140 79 360 6.9E-50 T 28-03-2018 CU254_RS28295 ed96e85b25cd80bf12cacd4be070b5dc 468 Pfam PF01979 Amidohydrolase family 65 428 3.7E-49 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CU254_RS28295 ed96e85b25cd80bf12cacd4be070b5dc 468 Gene3D G3DSA:3.20.20.140 361 429 0.018 T 28-03-2018 CU254_RS28295 ed96e85b25cd80bf12cacd4be070b5dc 468 Gene3D G3DSA:2.30.40.10 1 78 5.4E-19 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS28295 ed96e85b25cd80bf12cacd4be070b5dc 468 SUPERFAMILY SSF51338 379 454 1.95E-30 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS28295 ed96e85b25cd80bf12cacd4be070b5dc 468 SUPERFAMILY SSF51338 10 67 1.95E-30 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS28295 ed96e85b25cd80bf12cacd4be070b5dc 468 SUPERFAMILY SSF51556 67 377 2.18E-76 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS19705 12c280fa7b26632e740f35e83f7ab1ed 313 Gene3D G3DSA:1.10.1040.10 189 284 3.3E-18 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CU254_RS19705 12c280fa7b26632e740f35e83f7ab1ed 313 Gene3D G3DSA:3.40.50.720 1 188 4.7E-41 T 28-03-2018 CU254_RS19705 12c280fa7b26632e740f35e83f7ab1ed 313 PIRSF PIRSF000105 1 270 2.3E-62 T 28-03-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 CU254_RS19705 12c280fa7b26632e740f35e83f7ab1ed 313 PIRSF PIRSF000105 286 312 630.0 T 28-03-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 CU254_RS19705 12c280fa7b26632e740f35e83f7ab1ed 313 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 187 255 7.4E-14 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CU254_RS19705 12c280fa7b26632e740f35e83f7ab1ed 313 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 8 181 1.6E-41 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CU254_RS19705 12c280fa7b26632e740f35e83f7ab1ed 313 SUPERFAMILY SSF48179 187 274 1.02E-14 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CU254_RS19705 12c280fa7b26632e740f35e83f7ab1ed 313 SUPERFAMILY SSF51735 5 183 5.21E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS27725 fe8ba381c503338ab831b3414c371d82 469 Gene3D G3DSA:3.40.640.10 120 372 5.8E-38 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS27725 fe8ba381c503338ab831b3414c371d82 469 Gene3D G3DSA:1.10.10.10 2 68 2.6E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS27725 fe8ba381c503338ab831b3414c371d82 469 SUPERFAMILY SSF53383 102 465 7.17E-71 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS27725 fe8ba381c503338ab831b3414c371d82 469 SMART SM00345 9 66 2.4E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS27725 fe8ba381c503338ab831b3414c371d82 469 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 56 5.4E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS27725 fe8ba381c503338ab831b3414c371d82 469 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 26 40 5.4E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS27725 fe8ba381c503338ab831b3414c371d82 469 Gene3D G3DSA:3.90.1150.10 373 469 3.8E-22 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS27725 fe8ba381c503338ab831b3414c371d82 469 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 66 2.2E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS27725 fe8ba381c503338ab831b3414c371d82 469 Pfam PF00155 Aminotransferase class I and II 139 459 2.4E-19 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CU254_RS27725 fe8ba381c503338ab831b3414c371d82 469 SUPERFAMILY SSF46785 7 70 1.02E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS40570 0ef91bfb9ede8d37fe20e98cc835a68a 156 SUPERFAMILY SSF54909 66 155 7.51E-17 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS40570 0ef91bfb9ede8d37fe20e98cc835a68a 156 Gene3D G3DSA:3.30.70.920 58 151 1.1E-20 T 28-03-2018 CU254_RS40570 0ef91bfb9ede8d37fe20e98cc835a68a 156 Pfam PF01037 Lrp/AsnC ligand binding domain 72 145 7.9E-17 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CU254_RS40570 0ef91bfb9ede8d37fe20e98cc835a68a 156 Gene3D G3DSA:1.10.10.10 6 57 5.6E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS40570 0ef91bfb9ede8d37fe20e98cc835a68a 156 SUPERFAMILY SSF46785 6 65 4.5E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS40570 0ef91bfb9ede8d37fe20e98cc835a68a 156 Pfam PF13404 AsnC-type helix-turn-helix domain 6 47 5.3E-14 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS40570 0ef91bfb9ede8d37fe20e98cc835a68a 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 22 33 1.3E-12 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS40570 0ef91bfb9ede8d37fe20e98cc835a68a 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 6 22 1.3E-12 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS40570 0ef91bfb9ede8d37fe20e98cc835a68a 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 33 52 1.3E-12 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS40570 0ef91bfb9ede8d37fe20e98cc835a68a 156 SMART SM00344 6 115 4.6E-32 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CU254_RS09930 14d547c187aeec0ee508c7c2cfefe2cb 286 Pfam PF02405 Permease MlaE 70 273 1.1E-58 T 28-03-2018 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 CU254_RS02820 f9d6caa905df951d972c6b8af2df6f23 380 Gene3D G3DSA:3.40.50.2300 68 188 1.4E-33 T 28-03-2018 CU254_RS02820 f9d6caa905df951d972c6b8af2df6f23 380 SUPERFAMILY SSF53822 83 300 6.47E-8 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CU254_RS02820 f9d6caa905df951d972c6b8af2df6f23 380 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 75 367 5.6E-50 T 28-03-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 CU254_RS02820 f9d6caa905df951d972c6b8af2df6f23 380 Gene3D G3DSA:3.40.50.2300 189 379 1.5E-37 T 28-03-2018 CU254_RS25065 3a226b15d85f3edb96718e4c5e8255f9 209 SMART SM00882 6 202 1.6E-78 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CU254_RS25065 3a226b15d85f3edb96718e4c5e8255f9 209 SUPERFAMILY SSF100950 3 207 1.81E-72 T 28-03-2018 CU254_RS25065 3a226b15d85f3edb96718e4c5e8255f9 209 ProSitePatterns PS01274 Coenzyme A transferases signature 2. 44 52 - T 28-03-2018 IPR004164 Coenzyme A transferase active site GO:0008152|GO:0008410 Reactome: R-HSA-77108 CU254_RS25065 3a226b15d85f3edb96718e4c5e8255f9 209 Pfam PF01144 Coenzyme A transferase 6 201 4.2E-40 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CU254_RS25065 3a226b15d85f3edb96718e4c5e8255f9 209 Gene3D G3DSA:3.40.1080.10 3 208 1.1E-70 T 28-03-2018 CU254_RS25065 3a226b15d85f3edb96718e4c5e8255f9 209 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 3 206 1.8E-98 T 28-03-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 CU254_RS16150 26f5ef49bbca539ef6a46fa297cd329a 1052 SUPERFAMILY SSF56801 443 957 4.45E-148 T 28-03-2018 CU254_RS16150 26f5ef49bbca539ef6a46fa297cd329a 1052 ProSitePatterns PS00012 Phosphopantetheine attachment site. 969 984 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CU254_RS16150 26f5ef49bbca539ef6a46fa297cd329a 1052 Gene3D G3DSA:3.40.50.980 596 748 1.1E-36 T 28-03-2018 CU254_RS16150 26f5ef49bbca539ef6a46fa297cd329a 1052 Pfam PF13193 AMP-binding enzyme C-terminal domain 847 919 1.8E-9 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS16150 26f5ef49bbca539ef6a46fa297cd329a 1052 Pfam PF00501 AMP-binding enzyme 471 839 3.9E-97 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS16150 26f5ef49bbca539ef6a46fa297cd329a 1052 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 474 863 6.9E-131 T 28-03-2018 IPR010071 Amino acid adenylation domain CU254_RS16150 26f5ef49bbca539ef6a46fa297cd329a 1052 Pfam PF00550 Phosphopantetheine attachment site 947 1010 1.2E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS16150 26f5ef49bbca539ef6a46fa297cd329a 1052 Gene3D G3DSA:2.30.38.10 749 829 4.5E-24 T 28-03-2018 CU254_RS16150 26f5ef49bbca539ef6a46fa297cd329a 1052 ProSitePatterns PS00455 Putative AMP-binding domain signature. 590 601 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS16150 26f5ef49bbca539ef6a46fa297cd329a 1052 SUPERFAMILY SSF52777 6 174 8.34E-52 T 28-03-2018 CU254_RS16150 26f5ef49bbca539ef6a46fa297cd329a 1052 SUPERFAMILY SSF47336 938 1010 3.66E-18 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS16150 26f5ef49bbca539ef6a46fa297cd329a 1052 Gene3D G3DSA:3.30.300.30 834 950 1.4E-35 T 28-03-2018 CU254_RS16150 26f5ef49bbca539ef6a46fa297cd329a 1052 Gene3D G3DSA:3.30.559.10 1 180 6.7E-44 T 28-03-2018 CU254_RS16150 26f5ef49bbca539ef6a46fa297cd329a 1052 Pfam PF00668 Condensation domain 3 436 1.3E-91 T 28-03-2018 IPR001242 Condensation domain CU254_RS16150 26f5ef49bbca539ef6a46fa297cd329a 1052 Gene3D G3DSA:3.40.50.980 448 595 1.9E-43 T 28-03-2018 CU254_RS16150 26f5ef49bbca539ef6a46fa297cd329a 1052 Gene3D G3DSA:1.10.1200.10 951 1027 1.1E-21 T 28-03-2018 CU254_RS16150 26f5ef49bbca539ef6a46fa297cd329a 1052 SUPERFAMILY SSF52777 188 428 1.33E-56 T 28-03-2018 CU254_RS11065 c42d3cc5fc914a424454f11726b50091 181 Pfam PF11452 Protein of unknown function (DUF3000) 2 173 7.3E-70 T 28-03-2018 IPR021555 Protein of unknown function DUF3000 CU254_RS11465 2de5595ff55f4745d2073fd82c456c4d 198 SUPERFAMILY SSF53271 16 186 5.77E-41 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CU254_RS11465 2de5595ff55f4745d2073fd82c456c4d 198 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 14 192 34.815 T 28-03-2018 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CU254_RS11465 2de5595ff55f4745d2073fd82c456c4d 198 Gene3D G3DSA:3.40.50.2020 10 195 1.8E-35 T 28-03-2018 CU254_RS11465 2de5595ff55f4745d2073fd82c456c4d 198 Pfam PF00156 Phosphoribosyl transferase domain 16 162 1.1E-18 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CU254_RS03510 601a5f8f1f2d0b565f7310d8180f0602 837 Gene3D G3DSA:3.90.550.10 2 276 1.2E-47 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS03510 601a5f8f1f2d0b565f7310d8180f0602 837 SUPERFAMILY SSF53756 381 771 5.65E-29 T 28-03-2018 CU254_RS03510 601a5f8f1f2d0b565f7310d8180f0602 837 SUPERFAMILY SSF53448 6 232 6.91E-51 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS03510 601a5f8f1f2d0b565f7310d8180f0602 837 Gene3D G3DSA:3.40.50.2000 567 758 1.6E-27 T 28-03-2018 CU254_RS03510 601a5f8f1f2d0b565f7310d8180f0602 837 Pfam PF13641 Glycosyltransferase like family 2 9 231 7.3E-18 T 28-03-2018 CU254_RS03510 601a5f8f1f2d0b565f7310d8180f0602 837 Pfam PF00534 Glycosyl transferases group 1 575 750 4.2E-13 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CU254_RS19880 002923216dcacecd6a5e68ff551f56b8 395 Gene3D G3DSA:2.60.120.650 3 232 4.0E-23 T 28-03-2018 CU254_RS19880 002923216dcacecd6a5e68ff551f56b8 395 SMART SM00558 102 240 8.8E-4 T 28-03-2018 IPR003347 JmjC domain CU254_RS19880 002923216dcacecd6a5e68ff551f56b8 395 Pfam PF08007 Cupin superfamily protein 18 261 1.2E-42 T 28-03-2018 IPR003347 JmjC domain CU254_RS19880 002923216dcacecd6a5e68ff551f56b8 395 SUPERFAMILY SSF51197 10 284 6.32E-44 T 28-03-2018 CU254_RS09085 00f073cfe74f8227c61eb189ee29d02e 258 SUPERFAMILY SSF140453 6 96 8.24E-7 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CU254_RS09085 00f073cfe74f8227c61eb189ee29d02e 258 Gene3D G3DSA:1.10.287.1060 2 99 1.2E-5 T 28-03-2018 CU254_RS01935 a1fd09c3bafb5be5b005b3f9b4cc9786 699 Gene3D G3DSA:3.30.230.10 496 618 1.7E-44 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CU254_RS01935 a1fd09c3bafb5be5b005b3f9b4cc9786 699 TIGRFAM TIGR00484 EF-G: translation elongation factor G 7 696 0.0 T 28-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CU254_RS01935 a1fd09c3bafb5be5b005b3f9b4cc9786 699 Pfam PF03764 Elongation factor G, domain IV 481 602 1.2E-46 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CU254_RS01935 a1fd09c3bafb5be5b005b3f9b4cc9786 699 SUPERFAMILY SSF54980 406 483 2.05E-24 T 28-03-2018 IPR035647 EF-G domain III/V-like CU254_RS01935 a1fd09c3bafb5be5b005b3f9b4cc9786 699 Pfam PF14492 Elongation Factor G, domain II 406 480 1.3E-33 T 28-03-2018 CU254_RS01935 a1fd09c3bafb5be5b005b3f9b4cc9786 699 SUPERFAMILY SSF50447 267 406 1.16E-33 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CU254_RS01935 a1fd09c3bafb5be5b005b3f9b4cc9786 699 Pfam PF00009 Elongation factor Tu GTP binding domain 11 284 2.9E-67 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CU254_RS01935 a1fd09c3bafb5be5b005b3f9b4cc9786 699 SMART SM00889 482 603 3.6E-72 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CU254_RS01935 a1fd09c3bafb5be5b005b3f9b4cc9786 699 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 12 182 2.1E-35 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CU254_RS01935 a1fd09c3bafb5be5b005b3f9b4cc9786 699 SUPERFAMILY SSF54980 608 694 1.06E-30 T 28-03-2018 IPR035647 EF-G domain III/V-like CU254_RS01935 a1fd09c3bafb5be5b005b3f9b4cc9786 699 SUPERFAMILY SSF52540 8 284 3.97E-108 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS01935 a1fd09c3bafb5be5b005b3f9b4cc9786 699 Gene3D G3DSA:3.30.70.870 397 495 4.3E-36 T 28-03-2018 CU254_RS01935 a1fd09c3bafb5be5b005b3f9b4cc9786 699 PRINTS PR00315 GTP-binding elongation factor signature 80 90 1.3E-15 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CU254_RS01935 a1fd09c3bafb5be5b005b3f9b4cc9786 699 PRINTS PR00315 GTP-binding elongation factor signature 96 107 1.3E-15 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CU254_RS01935 a1fd09c3bafb5be5b005b3f9b4cc9786 699 PRINTS PR00315 GTP-binding elongation factor signature 14 27 1.3E-15 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CU254_RS01935 a1fd09c3bafb5be5b005b3f9b4cc9786 699 PRINTS PR00315 GTP-binding elongation factor signature 60 68 1.3E-15 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CU254_RS01935 a1fd09c3bafb5be5b005b3f9b4cc9786 699 PRINTS PR00315 GTP-binding elongation factor signature 132 141 1.3E-15 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CU254_RS01935 a1fd09c3bafb5be5b005b3f9b4cc9786 699 Pfam PF03144 Elongation factor Tu domain 2 326 393 3.4E-14 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CU254_RS01935 a1fd09c3bafb5be5b005b3f9b4cc9786 699 SUPERFAMILY SSF54211 481 604 1.95E-40 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CU254_RS01935 a1fd09c3bafb5be5b005b3f9b4cc9786 699 Gene3D G3DSA:2.40.30.10 276 396 1.4E-28 T 28-03-2018 CU254_RS01935 a1fd09c3bafb5be5b005b3f9b4cc9786 699 Pfam PF00679 Elongation factor G C-terminus 605 691 1.7E-30 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CU254_RS01935 a1fd09c3bafb5be5b005b3f9b4cc9786 699 SMART SM00838 605 692 5.3E-58 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CU254_RS01935 a1fd09c3bafb5be5b005b3f9b4cc9786 699 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 53 68 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site CU254_RS01935 a1fd09c3bafb5be5b005b3f9b4cc9786 699 Gene3D G3DSA:3.40.50.300 7 275 2.6E-60 T 28-03-2018 CU254_RS01935 a1fd09c3bafb5be5b005b3f9b4cc9786 699 Gene3D G3DSA:3.30.70.240 619 696 1.8E-32 T 28-03-2018 CU254_RS01935 a1fd09c3bafb5be5b005b3f9b4cc9786 699 Hamap MF_00054_B Elongation factor G [fusA]. 8 696 107.266 T 28-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CU254_RS19820 97df09f35b0d9d375a330bd652592d23 732 SUPERFAMILY SSF74650 30 295 2.2E-68 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CU254_RS19820 97df09f35b0d9d375a330bd652592d23 732 Gene3D G3DSA:1.50.10.10 659 721 8.2E-9 T 28-03-2018 CU254_RS19820 97df09f35b0d9d375a330bd652592d23 732 Gene3D G3DSA:1.50.10.10 283 658 9.3E-33 T 28-03-2018 CU254_RS19820 97df09f35b0d9d375a330bd652592d23 732 Pfam PF00723 Glycosyl hydrolases family 15 426 711 1.8E-12 T 28-03-2018 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: R-HSA-70221 CU254_RS19820 97df09f35b0d9d375a330bd652592d23 732 Gene3D G3DSA:2.70.98.10 15 282 5.5E-68 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 CU254_RS19820 97df09f35b0d9d375a330bd652592d23 732 SUPERFAMILY SSF48208 302 726 2.58E-47 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CU254_RS19820 97df09f35b0d9d375a330bd652592d23 732 Pfam PF09137 Glucodextranase, domain N 30 291 1.8E-82 T 28-03-2018 IPR015220 Glucodextranase, N-terminal KEGG: 00500+3.2.1.3|MetaCyc: PWY-5941 CU254_RS18365 6201f1ac62d2d5431dcda40349abd653 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 66 3.2E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS18365 6201f1ac62d2d5431dcda40349abd653 200 Gene3D G3DSA:1.10.10.60 1 56 1.0E-18 T 28-03-2018 CU254_RS18365 6201f1ac62d2d5431dcda40349abd653 200 SUPERFAMILY SSF48498 110 173 3.76E-8 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS18365 6201f1ac62d2d5431dcda40349abd653 200 Gene3D G3DSA:1.10.10.60 57 86 1.6E-9 T 28-03-2018 CU254_RS18365 6201f1ac62d2d5431dcda40349abd653 200 Gene3D G3DSA:1.10.357.10 87 196 4.9E-12 T 28-03-2018 CU254_RS18365 6201f1ac62d2d5431dcda40349abd653 200 SUPERFAMILY SSF46689 8 87 7.18E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS18365 6201f1ac62d2d5431dcda40349abd653 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 3.1E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS18365 6201f1ac62d2d5431dcda40349abd653 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 3.1E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS17025 fba45999f07ace78cc3044a24dcc1e30 206 SUPERFAMILY SSF46689 10 75 6.16E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS17025 fba45999f07ace78cc3044a24dcc1e30 206 Pfam PF16859 Bacterial transcriptional repressor C-terminal 81 191 3.3E-18 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS17025 fba45999f07ace78cc3044a24dcc1e30 206 SUPERFAMILY SSF48498 81 198 9.12E-9 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS17025 fba45999f07ace78cc3044a24dcc1e30 206 Gene3D G3DSA:1.10.10.60 3 63 5.4E-17 T 28-03-2018 CU254_RS17025 fba45999f07ace78cc3044a24dcc1e30 206 Gene3D G3DSA:1.10.357.10 64 199 2.4E-10 T 28-03-2018 CU254_RS17025 fba45999f07ace78cc3044a24dcc1e30 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 66 4.7E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS30355 6bf251e83184012d400254c9fce0810d 163 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 126 132 - T 28-03-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CU254_RS30355 6bf251e83184012d400254c9fce0810d 163 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 5 73 1.5E-5 T 28-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CU254_RS30355 6bf251e83184012d400254c9fce0810d 163 SUPERFAMILY SSF53155 4 80 9.02E-18 T 28-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CU254_RS30355 6bf251e83184012d400254c9fce0810d 163 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 76 155 6.2E-35 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CU254_RS30355 6bf251e83184012d400254c9fce0810d 163 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 77 156 4.7E-33 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CU254_RS30355 6bf251e83184012d400254c9fce0810d 163 SUPERFAMILY SSF46767 75 156 2.88E-32 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CU254_RS30355 6bf251e83184012d400254c9fce0810d 163 Gene3D G3DSA:1.10.10.10 71 157 3.9E-35 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS30355 6bf251e83184012d400254c9fce0810d 163 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 7 156 43.07 T 28-03-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 CU254_RS30355 6bf251e83184012d400254c9fce0810d 163 Gene3D G3DSA:3.30.160.70 1 70 6.3E-20 T 28-03-2018 CU254_RS41300 0c252c4a752e50d0990da916265e0a26 290 SMART SM00020 31 264 2.5E-27 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CU254_RS41300 0c252c4a752e50d0990da916265e0a26 290 Pfam PF00089 Trypsin 32 264 1.2E-32 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CU254_RS41300 0c252c4a752e50d0990da916265e0a26 290 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 64 79 1.1E-7 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CU254_RS41300 0c252c4a752e50d0990da916265e0a26 290 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 129 143 1.1E-7 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CU254_RS41300 0c252c4a752e50d0990da916265e0a26 290 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 213 225 1.1E-7 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CU254_RS41300 0c252c4a752e50d0990da916265e0a26 290 Gene3D G3DSA:2.40.10.10 73 279 5.4E-39 T 28-03-2018 CU254_RS41300 0c252c4a752e50d0990da916265e0a26 290 Gene3D G3DSA:2.40.10.10 32 72 3.2E-9 T 28-03-2018 CU254_RS41300 0c252c4a752e50d0990da916265e0a26 290 SUPERFAMILY SSF50494 9 269 5.91E-43 T 28-03-2018 IPR009003 Peptidase S1, PA clan CU254_RS06810 8493c34383167a9696b4828d401ab654 505 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 13 485 4.1E-190 T 28-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS06810 8493c34383167a9696b4828d401ab654 505 Pfam PF01425 Amidase 25 475 2.5E-159 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS06810 8493c34383167a9696b4828d401ab654 505 ProSitePatterns PS00571 Amidases signature. 154 185 - T 28-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CU254_RS06810 8493c34383167a9696b4828d401ab654 505 SUPERFAMILY SSF75304 3 486 4.71E-160 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS06810 8493c34383167a9696b4828d401ab654 505 PIRSF PIRSF001221 446 484 8.0 T 28-03-2018 CU254_RS06810 8493c34383167a9696b4828d401ab654 505 PIRSF PIRSF001221 2 456 2.4E-45 T 28-03-2018 CU254_RS06810 8493c34383167a9696b4828d401ab654 505 Gene3D G3DSA:3.90.1300.10 2 492 6.4E-165 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS06810 8493c34383167a9696b4828d401ab654 505 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 12 487 91.39 T 28-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS35830 b99eff6d452f9389c1130eb1f8de018b 204 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 173 3.4E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS35830 b99eff6d452f9389c1130eb1f8de018b 204 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 143 157 3.4E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS35830 b99eff6d452f9389c1130eb1f8de018b 204 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 185 3.4E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS35830 b99eff6d452f9389c1130eb1f8de018b 204 Pfam PF00072 Response regulator receiver domain 7 116 7.3E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS35830 b99eff6d452f9389c1130eb1f8de018b 204 SUPERFAMILY SSF52172 7 146 3.42E-29 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS35830 b99eff6d452f9389c1130eb1f8de018b 204 SMART SM00421 140 197 1.5E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS35830 b99eff6d452f9389c1130eb1f8de018b 204 SMART SM00448 5 116 1.8E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS35830 b99eff6d452f9389c1130eb1f8de018b 204 Gene3D G3DSA:1.10.10.10 140 196 2.7E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS35830 b99eff6d452f9389c1130eb1f8de018b 204 Pfam PF00196 Bacterial regulatory proteins, luxR family 142 194 6.6E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS35830 b99eff6d452f9389c1130eb1f8de018b 204 Gene3D G3DSA:3.40.50.2300 2 139 9.7E-26 T 28-03-2018 CU254_RS35830 b99eff6d452f9389c1130eb1f8de018b 204 SUPERFAMILY SSF46894 130 200 1.29E-17 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS34750 3b48cf707893f4355e43dac445ecece0 365 SUPERFAMILY SSF50129 4 186 1.38E-51 T 28-03-2018 IPR011032 GroES-like CU254_RS34750 3b48cf707893f4355e43dac445ecece0 365 SUPERFAMILY SSF50129 314 365 3.15E-8 T 28-03-2018 IPR011032 GroES-like CU254_RS34750 3b48cf707893f4355e43dac445ecece0 365 Pfam PF00107 Zinc-binding dehydrogenase 190 322 7.0E-25 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CU254_RS34750 3b48cf707893f4355e43dac445ecece0 365 SUPERFAMILY SSF51735 155 330 1.4E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS34750 3b48cf707893f4355e43dac445ecece0 365 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 148 9.4E-26 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CU254_RS34750 3b48cf707893f4355e43dac445ecece0 365 Gene3D G3DSA:3.40.50.10730 174 307 2.9E-32 T 28-03-2018 CU254_RS34750 3b48cf707893f4355e43dac445ecece0 365 Gene3D G3DSA:3.90.180.10 3 173 2.9E-42 T 28-03-2018 CU254_RS34750 3b48cf707893f4355e43dac445ecece0 365 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CU254_RS34750 3b48cf707893f4355e43dac445ecece0 365 TIGRFAM TIGR03451 mycoS_dep_FDH: S-(hydroxymethyl)mycothiol dehydrogenase 4 365 5.8E-203 T 28-03-2018 IPR017816 S-(hydroxymethyl)mycothiol dehydrogenase KEGG: 00072+1.1.1.30|KEGG: 00650+1.1.1.30 CU254_RS16175 39f425f7f5dbef52c85ace5593354a5e 280 Gene3D G3DSA:3.30.450.40 93 270 3.9E-19 T 28-03-2018 IPR029016 GAF domain-like CU254_RS16175 39f425f7f5dbef52c85ace5593354a5e 280 Gene3D G3DSA:1.10.10.10 21 91 4.7E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS16175 39f425f7f5dbef52c85ace5593354a5e 280 SUPERFAMILY SSF46785 26 89 4.18E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS16175 39f425f7f5dbef52c85ace5593354a5e 280 SMART SM00346 17 110 6.5E-5 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS16175 39f425f7f5dbef52c85ace5593354a5e 280 Pfam PF01614 Bacterial transcriptional regulator 146 262 2.4E-9 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal CU254_RS16175 39f425f7f5dbef52c85ace5593354a5e 280 SUPERFAMILY SSF55781 97 261 3.4E-17 T 28-03-2018 IPR029016 GAF domain-like CU254_RS16175 39f425f7f5dbef52c85ace5593354a5e 280 Pfam PF09339 IclR helix-turn-helix domain 28 74 1.0E-11 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS12180 68b9d29e21fb6fb39e6be7055f501bd7 494 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 252 259 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CU254_RS12180 68b9d29e21fb6fb39e6be7055f501bd7 494 Gene3D G3DSA:3.40.309.10 269 466 2.5E-64 T 28-03-2018 CU254_RS12180 68b9d29e21fb6fb39e6be7055f501bd7 494 Pfam PF00171 Aldehyde dehydrogenase family 25 479 1.7E-157 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CU254_RS12180 68b9d29e21fb6fb39e6be7055f501bd7 494 SUPERFAMILY SSF53720 10 483 1.83E-149 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CU254_RS12180 68b9d29e21fb6fb39e6be7055f501bd7 494 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 280 291 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CU254_RS12180 68b9d29e21fb6fb39e6be7055f501bd7 494 Gene3D G3DSA:3.40.605.10 6 268 3.0E-84 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CU254_RS07580 d9ea1dee9222f4e27eebbc8259d5d86b 196 Gene3D G3DSA:3.90.550.10 1 190 1.4E-34 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS07580 d9ea1dee9222f4e27eebbc8259d5d86b 196 SUPERFAMILY SSF53448 5 188 1.82E-30 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS07580 d9ea1dee9222f4e27eebbc8259d5d86b 196 Pfam PF12804 MobA-like NTP transferase domain 7 165 2.0E-37 T 28-03-2018 IPR025877 MobA-like NTP transferase CU254_RS04065 6a274a4bb67f059287c4a9771f03166c 325 Pfam PF13280 WYL domain 140 320 1.0E-42 T 28-03-2018 IPR026881 WYL domain CU254_RS04065 6a274a4bb67f059287c4a9771f03166c 325 PIRSF PIRSF016838 71 325 1.8E-12 T 28-03-2018 IPR028349 Protein PafC CU254_RS04065 6a274a4bb67f059287c4a9771f03166c 325 PIRSF PIRSF016838 1 53 4.8E-4 T 28-03-2018 IPR028349 Protein PafC CU254_RS04065 6a274a4bb67f059287c4a9771f03166c 325 Gene3D G3DSA:1.10.10.10 1 66 8.6E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS04065 6a274a4bb67f059287c4a9771f03166c 325 SUPERFAMILY SSF46785 3 59 3.2E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS04065 6a274a4bb67f059287c4a9771f03166c 325 Pfam PF08279 HTH domain 5 60 5.4E-18 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 CU254_RS30040 2966336875d17ba864d64ffee0d523f1 307 Gene3D G3DSA:3.40.50.300 4 261 4.7E-70 T 28-03-2018 CU254_RS30040 2966336875d17ba864d64ffee0d523f1 307 SUPERFAMILY SSF52540 6 228 3.03E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS30040 2966336875d17ba864d64ffee0d523f1 307 Pfam PF00005 ABC transporter 22 165 6.4E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS30040 2966336875d17ba864d64ffee0d523f1 307 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 14 301 2.6E-102 T 28-03-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 CU254_RS30040 2966336875d17ba864d64ffee0d523f1 307 SMART SM00382 31 214 5.4E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS30040 2966336875d17ba864d64ffee0d523f1 307 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS07985 b76d68535d46da824db36a68de6f2443 248 Gene3D G3DSA:1.10.1270.20 170 247 3.4E-31 T 28-03-2018 CU254_RS07985 b76d68535d46da824db36a68de6f2443 248 Gene3D G3DSA:3.40.1280.10 1 169 9.5E-72 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CU254_RS07985 b76d68535d46da824db36a68de6f2443 248 PIRSF PIRSF000386 1 246 2.1E-92 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CU254_RS07985 b76d68535d46da824db36a68de6f2443 248 SUPERFAMILY SSF75217 2 234 2.16E-89 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CU254_RS07985 b76d68535d46da824db36a68de6f2443 248 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 2 228 2.8E-75 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CU254_RS07985 b76d68535d46da824db36a68de6f2443 248 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 22 221 6.3E-69 T 28-03-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CU254_RS07985 b76d68535d46da824db36a68de6f2443 248 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 248 101.72 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CU254_RS24210 fac07be35cb6942afdccaee5e3a6a1f9 147 Pfam PF16708 Lipoprotein confined to pathogenic Mycobacterium 4 145 1.6E-22 T 28-03-2018 IPR032018 Putative lipoprotein, pathogenic bacteria CU254_RS18550 cc14f0b4679c95834debb1df8e6632ad 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 53 1.2E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS18550 cc14f0b4679c95834debb1df8e6632ad 188 SUPERFAMILY SSF48498 74 180 3.56E-13 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS18550 cc14f0b4679c95834debb1df8e6632ad 188 Gene3D G3DSA:1.10.357.10 53 181 2.5E-22 T 28-03-2018 CU254_RS18550 cc14f0b4679c95834debb1df8e6632ad 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 9.8E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS18550 cc14f0b4679c95834debb1df8e6632ad 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 9.8E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS18550 cc14f0b4679c95834debb1df8e6632ad 188 SUPERFAMILY SSF46689 3 71 1.85E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS18550 cc14f0b4679c95834debb1df8e6632ad 188 Gene3D G3DSA:1.10.10.60 2 52 1.4E-16 T 28-03-2018 CU254_RS09890 9e8f1de824f8ca61d9dc0d5092c5664a 390 SUPERFAMILY SSF52768 3 331 1.15E-109 T 28-03-2018 CU254_RS09890 9e8f1de824f8ca61d9dc0d5092c5664a 390 PRINTS PR01270 Histone deacetylase superfamily signature 125 148 7.2E-19 T 28-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CU254_RS09890 9e8f1de824f8ca61d9dc0d5092c5664a 390 PRINTS PR01270 Histone deacetylase superfamily signature 158 173 7.2E-19 T 28-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CU254_RS09890 9e8f1de824f8ca61d9dc0d5092c5664a 390 PRINTS PR01270 Histone deacetylase superfamily signature 244 254 7.2E-19 T 28-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CU254_RS09890 9e8f1de824f8ca61d9dc0d5092c5664a 390 Gene3D G3DSA:3.40.800.20 1 347 6.7E-99 T 28-03-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CU254_RS09890 9e8f1de824f8ca61d9dc0d5092c5664a 390 PRINTS PR01272 Acetoin utilisation ACUC protein signature 102 115 4.3E-9 T 28-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 CU254_RS09890 9e8f1de824f8ca61d9dc0d5092c5664a 390 PRINTS PR01272 Acetoin utilisation ACUC protein signature 15 35 4.3E-9 T 28-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 CU254_RS09890 9e8f1de824f8ca61d9dc0d5092c5664a 390 PRINTS PR01272 Acetoin utilisation ACUC protein signature 81 95 4.3E-9 T 28-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 CU254_RS09890 9e8f1de824f8ca61d9dc0d5092c5664a 390 Pfam PF00850 Histone deacetylase domain 21 314 6.9E-80 T 28-03-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CU254_RS32810 9495af9780e3e352336a84571a115739 323 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 288 2.4E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS32810 9495af9780e3e352336a84571a115739 323 Hamap MF_01685 Ferredoxin--NADP reductase. 2 322 38.97 T 28-03-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 CU254_RS32810 9495af9780e3e352336a84571a115739 323 Gene3D G3DSA:3.50.50.60 1 141 2.1E-19 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS32810 9495af9780e3e352336a84571a115739 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 149 167 1.8E-17 T 28-03-2018 CU254_RS32810 9495af9780e3e352336a84571a115739 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 259 281 1.8E-17 T 28-03-2018 CU254_RS32810 9495af9780e3e352336a84571a115739 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 233 249 1.8E-17 T 28-03-2018 CU254_RS32810 9495af9780e3e352336a84571a115739 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 1.8E-17 T 28-03-2018 CU254_RS32810 9495af9780e3e352336a84571a115739 323 SUPERFAMILY SSF51905 1 305 7.5E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS32810 9495af9780e3e352336a84571a115739 323 Gene3D G3DSA:3.40.50.720 142 316 9.5E-29 T 28-03-2018 CU254_RS32810 9495af9780e3e352336a84571a115739 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 145 169 1.8E-17 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CU254_RS32810 9495af9780e3e352336a84571a115739 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 4 26 1.8E-17 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CU254_RS32810 9495af9780e3e352336a84571a115739 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 108 116 1.8E-17 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CU254_RS32810 9495af9780e3e352336a84571a115739 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 61 71 1.8E-17 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CU254_RS32810 9495af9780e3e352336a84571a115739 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 269 287 1.8E-17 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CU254_RS30220 ea0a43c44019c306d5df9c49c6ef17fd 256 SMART SM00824 Thioesterase 27 248 2.6E-4 T 28-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 CU254_RS30220 ea0a43c44019c306d5df9c49c6ef17fd 256 Gene3D G3DSA:3.40.50.1820 4 250 4.7E-40 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS30220 ea0a43c44019c306d5df9c49c6ef17fd 256 Pfam PF00975 Thioesterase domain 25 246 9.7E-54 T 28-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CU254_RS30220 ea0a43c44019c306d5df9c49c6ef17fd 256 SUPERFAMILY SSF53474 5 248 3.24E-57 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS34850 9b01d941384028956b2950241e3ab52e 406 Gene3D G3DSA:2.30.40.10 330 391 5.0E-13 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS34850 9b01d941384028956b2950241e3ab52e 406 Gene3D G3DSA:2.30.40.10 1 67 1.8E-18 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS34850 9b01d941384028956b2950241e3ab52e 406 Pfam PF01979 Amidohydrolase family 245 376 8.2E-14 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CU254_RS34850 9b01d941384028956b2950241e3ab52e 406 Gene3D G3DSA:3.20.20.140 68 329 8.6E-26 T 28-03-2018 CU254_RS34850 9b01d941384028956b2950241e3ab52e 406 SUPERFAMILY SSF51338 351 388 4.17E-20 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS34850 9b01d941384028956b2950241e3ab52e 406 SUPERFAMILY SSF51338 5 59 4.17E-20 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS34850 9b01d941384028956b2950241e3ab52e 406 SUPERFAMILY SSF51556 58 352 9.83E-47 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS13815 12b858328205498a7e0d989dc057ce42 317 Pfam PF07859 alpha/beta hydrolase fold 80 289 3.3E-64 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CU254_RS13815 12b858328205498a7e0d989dc057ce42 317 SUPERFAMILY SSF53474 43 294 8.6E-65 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS13815 12b858328205498a7e0d989dc057ce42 317 Gene3D G3DSA:3.40.50.1820 1 316 1.3E-57 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS31485 2f5e69fb7ea82f6f26f8aec071186007 945 Pfam PF00486 Transcriptional regulatory protein, C terminal 37 102 3.5E-9 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS31485 2f5e69fb7ea82f6f26f8aec071186007 945 SUPERFAMILY SSF48452 107 269 1.43E-28 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS31485 2f5e69fb7ea82f6f26f8aec071186007 945 Gene3D G3DSA:1.10.10.10 5 104 3.2E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS31485 2f5e69fb7ea82f6f26f8aec071186007 945 Pfam PF13424 Tetratricopeptide repeat 787 854 2.7E-8 T 28-03-2018 CU254_RS31485 2f5e69fb7ea82f6f26f8aec071186007 945 SMART SM01043 109 253 2.5E-45 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CU254_RS31485 2f5e69fb7ea82f6f26f8aec071186007 945 SUPERFAMILY SSF52540 276 531 1.81E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS31485 2f5e69fb7ea82f6f26f8aec071186007 945 SUPERFAMILY SSF48452 738 941 4.93E-18 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS31485 2f5e69fb7ea82f6f26f8aec071186007 945 Gene3D G3DSA:1.25.40.10 679 800 1.3E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS31485 2f5e69fb7ea82f6f26f8aec071186007 945 Gene3D G3DSA:1.25.40.10 801 942 2.1E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS31485 2f5e69fb7ea82f6f26f8aec071186007 945 Gene3D G3DSA:1.25.40.10 107 270 5.6E-21 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS31485 2f5e69fb7ea82f6f26f8aec071186007 945 SMART SM00862 26 102 1.3E-9 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS31485 2f5e69fb7ea82f6f26f8aec071186007 945 SMART SM00028 823 856 90.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS31485 2f5e69fb7ea82f6f26f8aec071186007 945 SMART SM00028 703 736 0.59 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS31485 2f5e69fb7ea82f6f26f8aec071186007 945 SMART SM00028 863 896 46.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS31485 2f5e69fb7ea82f6f26f8aec071186007 945 SMART SM00028 783 816 18.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS31485 2f5e69fb7ea82f6f26f8aec071186007 945 SMART SM00028 903 936 250.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS31485 2f5e69fb7ea82f6f26f8aec071186007 945 Pfam PF03704 Bacterial transcriptional activator domain 109 253 1.5E-35 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CU254_RS31485 2f5e69fb7ea82f6f26f8aec071186007 945 Gene3D G3DSA:1.10.10.10 512 592 0.0033 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS31485 2f5e69fb7ea82f6f26f8aec071186007 945 Gene3D G3DSA:3.40.50.300 271 418 8.5E-15 T 28-03-2018 CU254_RS31485 2f5e69fb7ea82f6f26f8aec071186007 945 PRINTS PR00364 Disease resistance protein signature 464 478 2.0E-6 T 28-03-2018 CU254_RS31485 2f5e69fb7ea82f6f26f8aec071186007 945 PRINTS PR00364 Disease resistance protein signature 300 315 2.0E-6 T 28-03-2018 CU254_RS31485 2f5e69fb7ea82f6f26f8aec071186007 945 PRINTS PR00364 Disease resistance protein signature 379 393 2.0E-6 T 28-03-2018 CU254_RS31485 2f5e69fb7ea82f6f26f8aec071186007 945 SUPERFAMILY SSF46894 13 102 4.54E-10 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS31485 2f5e69fb7ea82f6f26f8aec071186007 945 Pfam PF00931 NB-ARC domain 294 533 6.0E-13 T 28-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 CU254_RS31520 5b93035beaaf4284de3f81b6c87cdda4 389 Pfam PF06224 Winged helix DNA-binding domain 30 365 3.6E-48 T 28-03-2018 IPR009351 Protein of unknown function DUF1006 CU254_RS31520 5b93035beaaf4284de3f81b6c87cdda4 389 Gene3D G3DSA:1.10.10.10 209 255 0.12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS12385 0349d57f327eadea753775869ecfbdcb 328 Pfam PF02332 Methane/Phenol/Toluene Hydroxylase 54 272 9.1E-68 T 28-03-2018 IPR003430 Methane/phenol/toluene hydroxylase GO:0006725|GO:0055114 CU254_RS12385 0349d57f327eadea753775869ecfbdcb 328 Gene3D G3DSA:1.10.620.20 2 325 6.7E-91 T 28-03-2018 CU254_RS12385 0349d57f327eadea753775869ecfbdcb 328 SUPERFAMILY SSF47240 5 324 5.0E-86 T 28-03-2018 IPR009078 Ferritin-like superfamily CU254_RS12385 0349d57f327eadea753775869ecfbdcb 328 PIRSF PIRSF000040 1 328 7.4E-97 T 28-03-2018 IPR012078 Methane/phenol monooxygenase, hydroxylase component GO:0016709|GO:0055114 CU254_RS15965 c59c2cb0b919772fe7ebf8ad611009c4 292 Pfam PF01636 Phosphotransferase enzyme family 29 251 7.3E-33 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CU254_RS15965 c59c2cb0b919772fe7ebf8ad611009c4 292 SUPERFAMILY SSF56112 9 258 2.19E-46 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS15965 c59c2cb0b919772fe7ebf8ad611009c4 292 Gene3D G3DSA:1.10.510.10 49 279 5.4E-26 T 28-03-2018 CU254_RS08605 87a669579cc7c77173ae546cfd8c4dfa 931 Gene3D G3DSA:3.40.50.970 78 500 5.8E-87 T 28-03-2018 CU254_RS08605 87a669579cc7c77173ae546cfd8c4dfa 931 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 29 921 0.0 T 28-03-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 CU254_RS08605 87a669579cc7c77173ae546cfd8c4dfa 931 PIRSF PIRSF000156 19 925 0.0 T 28-03-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 CU254_RS08605 87a669579cc7c77173ae546cfd8c4dfa 931 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 159 327 1.5E-9 T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CU254_RS08605 87a669579cc7c77173ae546cfd8c4dfa 931 Gene3D G3DSA:3.40.50.970 501 741 3.1E-68 T 28-03-2018 CU254_RS08605 87a669579cc7c77173ae546cfd8c4dfa 931 SUPERFAMILY SSF52922 740 917 1.47E-51 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CU254_RS08605 87a669579cc7c77173ae546cfd8c4dfa 931 SUPERFAMILY SSF52518 504 736 3.09E-86 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS08605 87a669579cc7c77173ae546cfd8c4dfa 931 SUPERFAMILY SSF52518 79 499 3.34E-132 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS08605 87a669579cc7c77173ae546cfd8c4dfa 931 Gene3D G3DSA:3.40.50.920 743 925 3.8E-40 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CU254_RS33025 f4eac0e0a72145e4cca498c71b61b9ad 406 Pfam PF00108 Thiolase, N-terminal domain 5 274 8.4E-57 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CU254_RS33025 f4eac0e0a72145e4cca498c71b61b9ad 406 SUPERFAMILY SSF53901 283 404 2.38E-43 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS33025 f4eac0e0a72145e4cca498c71b61b9ad 406 PIRSF PIRSF000429 1 406 2.0E-128 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CU254_RS33025 f4eac0e0a72145e4cca498c71b61b9ad 406 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 403 1.4E-136 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CU254_RS33025 f4eac0e0a72145e4cca498c71b61b9ad 406 SUPERFAMILY SSF53901 3 282 2.31E-66 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS33025 f4eac0e0a72145e4cca498c71b61b9ad 406 Gene3D G3DSA:3.40.47.10 1 277 5.0E-53 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS33025 f4eac0e0a72145e4cca498c71b61b9ad 406 Pfam PF02803 Thiolase, C-terminal domain 282 404 4.1E-48 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CU254_RS33025 f4eac0e0a72145e4cca498c71b61b9ad 406 Gene3D G3DSA:3.40.47.10 278 402 1.3E-34 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS33025 f4eac0e0a72145e4cca498c71b61b9ad 406 ProSitePatterns PS00737 Thiolases signature 2. 351 367 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CU254_RS33460 aae1ef4658dc2742508eea3abefd69ec 434 ProSitePatterns PS00216 Sugar transport proteins signature 1. 104 120 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CU254_RS33460 aae1ef4658dc2742508eea3abefd69ec 434 SUPERFAMILY SSF103473 34 430 4.05E-66 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS33460 aae1ef4658dc2742508eea3abefd69ec 434 ProSitePatterns PS00217 Sugar transport proteins signature 2. 146 171 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CU254_RS33460 aae1ef4658dc2742508eea3abefd69ec 434 Pfam PF07690 Major Facilitator Superfamily 55 330 5.1E-29 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS33460 aae1ef4658dc2742508eea3abefd69ec 434 Gene3D G3DSA:1.20.1250.20 248 434 1.1E-21 T 28-03-2018 CU254_RS33460 aae1ef4658dc2742508eea3abefd69ec 434 Gene3D G3DSA:1.20.1250.20 40 237 3.3E-32 T 28-03-2018 CU254_RS00315 3a44c8d8e66e004c8f9a7ddee3c2851f 272 Pfam PF13676 TIR domain 81 203 8.4E-15 T 28-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 CU254_RS00315 3a44c8d8e66e004c8f9a7ddee3c2851f 272 Gene3D G3DSA:3.40.50.10140 74 232 4.0E-15 T 28-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 CU254_RS00315 3a44c8d8e66e004c8f9a7ddee3c2851f 272 SUPERFAMILY SSF52200 73 188 1.44E-8 T 28-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 CU254_RS25415 1180dff02dcb232875c0acfa848b5a04 368 SUPERFAMILY SSF53822 43 354 8.78E-69 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CU254_RS25415 1180dff02dcb232875c0acfa848b5a04 368 Pfam PF13407 Periplasmic binding protein domain 45 320 1.0E-66 T 28-03-2018 IPR025997 Periplasmic binding protein CU254_RS25415 1180dff02dcb232875c0acfa848b5a04 368 Gene3D G3DSA:3.40.50.2300 42 198 1.2E-32 T 28-03-2018 CU254_RS25415 1180dff02dcb232875c0acfa848b5a04 368 Gene3D G3DSA:3.40.50.2300 204 342 2.6E-16 T 28-03-2018 CU254_RS19935 5a3f29317c47c81e6ced66ec2968a8a2 642 SUPERFAMILY SSF46977 502 641 2.62E-40 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CU254_RS19935 5a3f29317c47c81e6ced66ec2968a8a2 642 Pfam PF00890 FAD binding domain 44 449 3.5E-56 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CU254_RS19935 5a3f29317c47c81e6ced66ec2968a8a2 642 Gene3D G3DSA:1.20.58.100 481 599 1.3E-29 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CU254_RS19935 5a3f29317c47c81e6ced66ec2968a8a2 642 Gene3D G3DSA:3.50.50.60 31 315 1.0E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS19935 5a3f29317c47c81e6ced66ec2968a8a2 642 Gene3D G3DSA:3.50.50.60 341 471 2.0E-10 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS19935 5a3f29317c47c81e6ced66ec2968a8a2 642 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 44 63 5.1E-5 T 28-03-2018 CU254_RS19935 5a3f29317c47c81e6ced66ec2968a8a2 642 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 413 435 5.1E-5 T 28-03-2018 CU254_RS19935 5a3f29317c47c81e6ced66ec2968a8a2 642 Pfam PF02910 Fumarate reductase flavoprotein C-term 510 641 7.5E-34 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CU254_RS19935 5a3f29317c47c81e6ced66ec2968a8a2 642 SUPERFAMILY SSF51905 414 459 1.4E-49 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS19935 5a3f29317c47c81e6ced66ec2968a8a2 642 SUPERFAMILY SSF51905 41 285 1.4E-49 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS19935 5a3f29317c47c81e6ced66ec2968a8a2 642 SUPERFAMILY SSF56425 269 411 5.53E-32 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CU254_RS19935 5a3f29317c47c81e6ced66ec2968a8a2 642 TIGRFAM TIGR01811 sdhA_Bsu: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 44 641 3.0E-300 T 28-03-2018 IPR011280 Succinate dehydrogenase/fumarate reductase flavoprotein subunit, low-GC Gram-positive bacteria KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279 CU254_RS12065 632f4b997385630db9c092ef38672334 340 Pfam PF08279 HTH domain 7 62 1.9E-13 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 CU254_RS12065 632f4b997385630db9c092ef38672334 340 SUPERFAMILY SSF46785 4 63 1.15E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS12065 632f4b997385630db9c092ef38672334 340 Pfam PF13280 WYL domain 140 313 4.0E-29 T 28-03-2018 IPR026881 WYL domain CU254_RS12065 632f4b997385630db9c092ef38672334 340 Gene3D G3DSA:1.10.10.10 3 65 6.3E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS23715 b56a45c0750c6f5eec4e37e899fd34dc 355 Gene3D G3DSA:3.30.1780.10 18 158 5.2E-39 T 28-03-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 CU254_RS23715 b56a45c0750c6f5eec4e37e899fd34dc 355 Gene3D G3DSA:3.40.50.720 159 319 1.6E-12 T 28-03-2018 CU254_RS23715 b56a45c0750c6f5eec4e37e899fd34dc 355 TIGRFAM TIGR03944 dehyd_SbnB_fam: 2,3-diaminopropionate biosynthesis protein SbnB 22 347 1.5E-127 T 28-03-2018 IPR023866 2,3-diaminopropionate biosynthesis protein SbnB CU254_RS23715 b56a45c0750c6f5eec4e37e899fd34dc 355 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 36 337 2.3E-33 T 28-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CU254_RS23715 b56a45c0750c6f5eec4e37e899fd34dc 355 PIRSF PIRSF001439 16 347 2.9E-78 T 28-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CU254_RS23715 b56a45c0750c6f5eec4e37e899fd34dc 355 SUPERFAMILY SSF51735 21 346 1.93E-65 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS06145 0ef632acf157ea1cc81113a4585d79b5 258 Pfam PF00005 ABC transporter 32 172 2.9E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS06145 0ef632acf157ea1cc81113a4585d79b5 258 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS06145 0ef632acf157ea1cc81113a4585d79b5 258 Gene3D G3DSA:3.40.50.300 9 245 5.8E-55 T 28-03-2018 CU254_RS06145 0ef632acf157ea1cc81113a4585d79b5 258 SUPERFAMILY SSF52540 13 241 3.73E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS06145 0ef632acf157ea1cc81113a4585d79b5 258 SMART SM00382 41 223 4.0E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS23110 08356b98e4b603115f7de4453fa5a411 372 Pfam PF11199 Protein of unknown function (DUF2891) 60 357 1.8E-35 T 28-03-2018 IPR021365 Protein of unknown function DUF2891 CU254_RS23110 08356b98e4b603115f7de4453fa5a411 372 Gene3D G3DSA:1.50.10.10 55 267 1.1E-5 T 28-03-2018 CU254_RS23110 08356b98e4b603115f7de4453fa5a411 372 SUPERFAMILY SSF48208 70 213 1.22E-5 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CU254_RS03650 bafdec8b5af81fdd1fac6a0ba1b592d5 696 SMART SM00495 648 693 0.0013 T 28-03-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 CU254_RS03650 bafdec8b5af81fdd1fac6a0ba1b592d5 696 Gene3D G3DSA:2.60.40.10 539 632 5.8E-8 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS03650 bafdec8b5af81fdd1fac6a0ba1b592d5 696 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 361 523 4.7E-35 T 28-03-2018 IPR001570 Peptidase M4, C-terminal GO:0004222 CU254_RS03650 bafdec8b5af81fdd1fac6a0ba1b592d5 696 Pfam PF03413 Peptidase propeptide and YPEB domain 130 192 3.0E-6 T 28-03-2018 IPR025711 PepSY domain CU254_RS03650 bafdec8b5af81fdd1fac6a0ba1b592d5 696 SUPERFAMILY SSF51055 645 696 2.75E-9 T 28-03-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 CU254_RS03650 bafdec8b5af81fdd1fac6a0ba1b592d5 696 Gene3D G3DSA:1.10.390.10 359 528 1.2E-38 T 28-03-2018 CU254_RS03650 bafdec8b5af81fdd1fac6a0ba1b592d5 696 Gene3D G3DSA:2.10.10.20 633 696 4.5E-11 T 28-03-2018 CU254_RS03650 bafdec8b5af81fdd1fac6a0ba1b592d5 696 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 364 375 2.0E-6 T 28-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 CU254_RS03650 bafdec8b5af81fdd1fac6a0ba1b592d5 696 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 308 328 2.0E-6 T 28-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 CU254_RS03650 bafdec8b5af81fdd1fac6a0ba1b592d5 696 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 429 445 2.0E-6 T 28-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 CU254_RS03650 bafdec8b5af81fdd1fac6a0ba1b592d5 696 SUPERFAMILY SSF55486 213 524 4.98E-60 T 28-03-2018 CU254_RS03650 bafdec8b5af81fdd1fac6a0ba1b592d5 696 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 215 351 2.0E-28 T 28-03-2018 IPR013856 Peptidase M4 domain GO:0004222 CU254_RS03650 bafdec8b5af81fdd1fac6a0ba1b592d5 696 Gene3D G3DSA:3.10.170.10 213 355 4.1E-30 T 28-03-2018 CU254_RS38955 d1a7e838d66ff871d210600ff97b671b 154 SUPERFAMILY SSF55658 3 57 1.29E-16 T 28-03-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal CU254_RS38955 d1a7e838d66ff871d210600ff97b671b 154 Pfam PF01281 Ribosomal protein L9, N-terminal domain 3 47 6.0E-20 T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS38955 d1a7e838d66ff871d210600ff97b671b 154 SUPERFAMILY SSF55653 59 148 1.7E-19 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal CU254_RS38955 d1a7e838d66ff871d210600ff97b671b 154 ProSitePatterns PS00651 Ribosomal protein L9 signature. 14 41 - T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS38955 d1a7e838d66ff871d210600ff97b671b 154 TIGRFAM TIGR00158 L9: ribosomal protein bL9 3 150 1.6E-31 T 28-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS38955 d1a7e838d66ff871d210600ff97b671b 154 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 2 151 23.529 T 28-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS38955 d1a7e838d66ff871d210600ff97b671b 154 Pfam PF03948 Ribosomal protein L9, C-terminal domain 65 150 2.9E-21 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal CU254_RS38955 d1a7e838d66ff871d210600ff97b671b 154 Gene3D G3DSA:3.40.5.10 3 50 5.8E-20 T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS38955 d1a7e838d66ff871d210600ff97b671b 154 Gene3D G3DSA:3.10.430.100 64 150 5.3E-22 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal CU254_RS07570 68f657b5971f5e81d603a3fa9aaf740f 124 SUPERFAMILY SSF69118 1 119 3.14E-36 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CU254_RS07570 68f657b5971f5e81d603a3fa9aaf740f 124 TIGRFAM TIGR02425 decarb_PcaC: 4-carboxymuconolactone decarboxylase 1 114 6.8E-49 T 28-03-2018 IPR012788 4-carboxymuconolactone decarboxylase KEGG: 00362+4.1.1.44 CU254_RS07570 68f657b5971f5e81d603a3fa9aaf740f 124 Gene3D G3DSA:1.20.1290.10 4 124 4.6E-39 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CU254_RS07570 68f657b5971f5e81d603a3fa9aaf740f 124 Pfam PF02627 Carboxymuconolactone decarboxylase family 27 108 2.4E-25 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CU254_RS37260 757e68dc8aec6bc3b8dde8360a99f1ca 816 Gene3D G3DSA:3.60.10.10 488 790 2.7E-29 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CU254_RS37260 757e68dc8aec6bc3b8dde8360a99f1ca 816 SUPERFAMILY SSF56219 488 789 3.4E-30 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CU254_RS37260 757e68dc8aec6bc3b8dde8360a99f1ca 816 Gene3D G3DSA:2.60.40.1260 15 138 8.9E-11 T 28-03-2018 IPR001322 Lamin Tail Domain CU254_RS37260 757e68dc8aec6bc3b8dde8360a99f1ca 816 Pfam PF00932 Lamin Tail Domain 24 114 2.1E-8 T 28-03-2018 IPR001322 Lamin Tail Domain CU254_RS37260 757e68dc8aec6bc3b8dde8360a99f1ca 816 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 491 782 3.1E-9 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CU254_RS13930 05909419547970c314ae28630f5898ae 289 Pfam PF00494 Squalene/phytoene synthase 19 274 3.7E-68 T 28-03-2018 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 CU254_RS13930 05909419547970c314ae28630f5898ae 289 ProSitePatterns PS01045 Squalene and phytoene synthases signature 2. 159 184 - T 28-03-2018 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CU254_RS13930 05909419547970c314ae28630f5898ae 289 SUPERFAMILY SSF48576 10 286 7.05E-71 T 28-03-2018 IPR008949 Isoprenoid synthase domain CU254_RS13930 05909419547970c314ae28630f5898ae 289 TIGRFAM TIGR03465 HpnD: squalene synthase HpnD 18 284 2.7E-85 T 28-03-2018 IPR017828 Squalene/phytoene synthase HpnD GO:0016117|GO:0016767 CU254_RS13930 05909419547970c314ae28630f5898ae 289 Gene3D G3DSA:1.10.600.10 3 289 1.0E-82 T 28-03-2018 IPR008949 Isoprenoid synthase domain CU254_RS16730 b40a9157e28b3b811dde2c092d40264c 702 Gene3D G3DSA:2.115.10.10 63 232 3.2E-6 T 28-03-2018 CU254_RS16730 b40a9157e28b3b811dde2c092d40264c 702 Pfam PF14517 Tachylectin 69 230 6.2E-13 T 28-03-2018 IPR023294 Tachylectin 2 CU254_RS16730 b40a9157e28b3b811dde2c092d40264c 702 SUPERFAMILY SSF50934 73 201 2.09E-6 T 28-03-2018 IPR023294 Tachylectin 2 CU254_RS16730 b40a9157e28b3b811dde2c092d40264c 702 Gene3D G3DSA:3.40.50.880 407 698 7.8E-23 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS40500 7da604699dcb408ab6c423969fd03373 253 Gene3D G3DSA:2.40.10.10 150 253 5.3E-16 T 28-03-2018 CU254_RS40500 7da604699dcb408ab6c423969fd03373 253 SUPERFAMILY SSF50494 32 238 1.25E-21 T 28-03-2018 IPR009003 Peptidase S1, PA clan CU254_RS40500 7da604699dcb408ab6c423969fd03373 253 Gene3D G3DSA:2.40.10.10 37 149 1.4E-10 T 28-03-2018 CU254_RS40500 7da604699dcb408ab6c423969fd03373 253 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 72 77 - T 28-03-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 CU254_RS24315 58f8f48ece06f6c3b65bac07ef18c3e1 609 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 12 607 3.6E-234 T 28-03-2018 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 CU254_RS24315 58f8f48ece06f6c3b65bac07ef18c3e1 609 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 13 464 3.8E-153 T 28-03-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 CU254_RS24315 58f8f48ece06f6c3b65bac07ef18c3e1 609 SMART SM00341 536 609 2.3E-13 T 28-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 CU254_RS24315 58f8f48ece06f6c3b65bac07ef18c3e1 609 SMART SM00956 409 515 1.3E-42 T 28-03-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 CU254_RS24315 58f8f48ece06f6c3b65bac07ef18c3e1 609 Pfam PF09382 RQC domain 404 518 2.3E-33 T 28-03-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 CU254_RS24315 58f8f48ece06f6c3b65bac07ef18c3e1 609 SUPERFAMILY SSF47819 535 608 1.94E-21 T 28-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 CU254_RS24315 58f8f48ece06f6c3b65bac07ef18c3e1 609 Pfam PF00270 DEAD/DEAH box helicase 26 185 7.2E-18 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CU254_RS24315 58f8f48ece06f6c3b65bac07ef18c3e1 609 SMART SM00487 19 215 2.2E-27 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CU254_RS24315 58f8f48ece06f6c3b65bac07ef18c3e1 609 Pfam PF00570 HRDC domain 541 605 5.9E-22 T 28-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 CU254_RS24315 58f8f48ece06f6c3b65bac07ef18c3e1 609 Pfam PF16124 RecQ zinc-binding 341 402 4.6E-19 T 28-03-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain CU254_RS24315 58f8f48ece06f6c3b65bac07ef18c3e1 609 Gene3D G3DSA:3.40.50.300 2 205 1.1E-31 T 28-03-2018 CU254_RS24315 58f8f48ece06f6c3b65bac07ef18c3e1 609 Gene3D G3DSA:3.40.50.300 207 350 5.4E-28 T 28-03-2018 CU254_RS24315 58f8f48ece06f6c3b65bac07ef18c3e1 609 Gene3D G3DSA:1.10.10.10 351 524 3.0E-48 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS24315 58f8f48ece06f6c3b65bac07ef18c3e1 609 Gene3D G3DSA:1.10.150.80 539 608 4.3E-24 T 28-03-2018 CU254_RS24315 58f8f48ece06f6c3b65bac07ef18c3e1 609 SMART SM00490 248 329 3.8E-24 T 28-03-2018 IPR001650 Helicase, C-terminal CU254_RS24315 58f8f48ece06f6c3b65bac07ef18c3e1 609 SUPERFAMILY SSF52540 8 194 2.45E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS24315 58f8f48ece06f6c3b65bac07ef18c3e1 609 Pfam PF00271 Helicase conserved C-terminal domain 223 328 1.9E-16 T 28-03-2018 IPR001650 Helicase, C-terminal CU254_RS24315 58f8f48ece06f6c3b65bac07ef18c3e1 609 SUPERFAMILY SSF52540 205 456 1.17E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS34910 817ccdb55e012ebda9f1fb2636cc987e 542 Gene3D G3DSA:3.40.50.970 337 540 1.4E-35 T 28-03-2018 CU254_RS34910 817ccdb55e012ebda9f1fb2636cc987e 542 SUPERFAMILY SSF52518 2 165 4.79E-33 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS34910 817ccdb55e012ebda9f1fb2636cc987e 542 Gene3D G3DSA:3.40.50.1220 188 336 9.1E-31 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CU254_RS34910 817ccdb55e012ebda9f1fb2636cc987e 542 SUPERFAMILY SSF52467 178 345 1.42E-28 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CU254_RS34910 817ccdb55e012ebda9f1fb2636cc987e 542 SUPERFAMILY SSF52518 356 529 2.5E-42 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS34910 817ccdb55e012ebda9f1fb2636cc987e 542 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 185 313 4.5E-21 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CU254_RS34910 817ccdb55e012ebda9f1fb2636cc987e 542 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 380 524 5.3E-27 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CU254_RS34910 817ccdb55e012ebda9f1fb2636cc987e 542 Gene3D G3DSA:3.40.50.970 1 187 2.8E-34 T 28-03-2018 CU254_RS34910 817ccdb55e012ebda9f1fb2636cc987e 542 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 2 163 4.4E-38 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CU254_RS17020 58b88b7e2d78fe3d0a36d4ad6cd9190e 302 Gene3D G3DSA:3.40.190.10 181 249 5.4E-25 T 28-03-2018 CU254_RS17020 58b88b7e2d78fe3d0a36d4ad6cd9190e 302 Gene3D G3DSA:3.40.190.10 90 180 1.2E-18 T 28-03-2018 CU254_RS17020 58b88b7e2d78fe3d0a36d4ad6cd9190e 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 5.3E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS17020 58b88b7e2d78fe3d0a36d4ad6cd9190e 302 Pfam PF03466 LysR substrate binding domain 88 293 3.5E-40 T 28-03-2018 IPR005119 LysR, substrate-binding CU254_RS17020 58b88b7e2d78fe3d0a36d4ad6cd9190e 302 Gene3D G3DSA:1.10.10.10 1 87 2.5E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS17020 58b88b7e2d78fe3d0a36d4ad6cd9190e 302 SUPERFAMILY SSF46785 1 110 1.29E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS17020 58b88b7e2d78fe3d0a36d4ad6cd9190e 302 Gene3D G3DSA:1.10.10.10 250 302 0.22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS17020 58b88b7e2d78fe3d0a36d4ad6cd9190e 302 SUPERFAMILY SSF53850 88 299 6.98E-35 T 28-03-2018 CU254_RS15410 068a3cc6c325c3ee7f15db2f7959e5ea 106 Pfam PF12277 Protein of unknown function (DUF3618) 4 48 3.6E-8 T 28-03-2018 IPR022062 Protein of unknown function DUF3618 CU254_RS27770 eef0e9fb530d468838abe74705c61272 458 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 78 2.0E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS27770 eef0e9fb530d468838abe74705c61272 458 Gene3D G3DSA:3.90.1150.10 359 456 1.6E-11 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS27770 eef0e9fb530d468838abe74705c61272 458 SMART SM00345 20 79 1.1E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS27770 eef0e9fb530d468838abe74705c61272 458 SUPERFAMILY SSF46785 16 89 2.18E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS27770 eef0e9fb530d468838abe74705c61272 458 SUPERFAMILY SSF53383 91 452 2.15E-67 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS27770 eef0e9fb530d468838abe74705c61272 458 Gene3D G3DSA:1.10.10.10 9 81 7.6E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS27770 eef0e9fb530d468838abe74705c61272 458 Gene3D G3DSA:3.40.640.10 116 358 1.5E-38 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS27770 eef0e9fb530d468838abe74705c61272 458 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 39 53 7.2E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS27770 eef0e9fb530d468838abe74705c61272 458 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 53 69 7.2E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS27770 eef0e9fb530d468838abe74705c61272 458 Pfam PF00155 Aminotransferase class I and II 124 409 8.7E-20 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CU254_RS42555 742cf366e7a4b18a89c89b131c8175a3 145 Gene3D G3DSA:1.10.10.60 18 92 3.6E-6 T 28-03-2018 CU254_RS42555 742cf366e7a4b18a89c89b131c8175a3 145 Gene3D G3DSA:1.10.10.10 93 135 3.2E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS42555 742cf366e7a4b18a89c89b131c8175a3 145 Pfam PF12728 Helix-turn-helix domain 80 123 1.5E-11 T 28-03-2018 CU254_RS42555 742cf366e7a4b18a89c89b131c8175a3 145 SUPERFAMILY SSF46955 79 133 1.43E-5 T 28-03-2018 IPR009061 Putative DNA-binding domain CU254_RS42555 742cf366e7a4b18a89c89b131c8175a3 145 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 80 121 2.7E-13 T 28-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 CU254_RS25295 0a0e28824f8b2055bd429b8679ea22ba 365 Gene3D G3DSA:3.50.50.60 1 365 5.9E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS25295 0a0e28824f8b2055bd429b8679ea22ba 365 SUPERFAMILY SSF54373 218 307 8.63E-17 T 28-03-2018 CU254_RS25295 0a0e28824f8b2055bd429b8679ea22ba 365 Pfam PF01266 FAD dependent oxidoreductase 2 347 1.1E-52 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CU254_RS25295 0a0e28824f8b2055bd429b8679ea22ba 365 SUPERFAMILY SSF51905 1 218 4.27E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS25295 0a0e28824f8b2055bd429b8679ea22ba 365 SUPERFAMILY SSF51905 309 365 4.27E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS23270 303e1a4001ea776d57f5f494d7d2b5ef 232 Pfam PF03591 AzlC protein 19 155 7.7E-33 T 28-03-2018 IPR011606 Branched-chain amino acid transport, permease CU254_RS34315 e4195640ff8095d71fa0b4de464bdc6f 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 69 2.7E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS34315 e4195640ff8095d71fa0b4de464bdc6f 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 5.7E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS34315 e4195640ff8095d71fa0b4de464bdc6f 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 5.7E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS34315 e4195640ff8095d71fa0b4de464bdc6f 206 Gene3D G3DSA:1.10.357.10 76 199 3.8E-8 T 28-03-2018 CU254_RS34315 e4195640ff8095d71fa0b4de464bdc6f 206 Gene3D G3DSA:1.10.10.60 2 44 2.6E-14 T 28-03-2018 CU254_RS34315 e4195640ff8095d71fa0b4de464bdc6f 206 SUPERFAMILY SSF46689 10 90 7.56E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS34315 e4195640ff8095d71fa0b4de464bdc6f 206 Gene3D G3DSA:1.10.260.40 45 75 2.7E-14 T 28-03-2018 CU254_RS36860 4c22cdc8705cf56e5ff0b1679e1a5507 615 Gene3D G3DSA:2.140.10.30 18 351 2.3E-21 T 28-03-2018 CU254_RS36860 4c22cdc8705cf56e5ff0b1679e1a5507 615 Gene3D G3DSA:3.40.50.1820 352 615 9.9E-49 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS36860 4c22cdc8705cf56e5ff0b1679e1a5507 615 SUPERFAMILY SSF69304 157 324 1.03E-18 T 28-03-2018 CU254_RS36860 4c22cdc8705cf56e5ff0b1679e1a5507 615 SUPERFAMILY SSF69304 40 103 1.03E-18 T 28-03-2018 CU254_RS36860 4c22cdc8705cf56e5ff0b1679e1a5507 615 SUPERFAMILY SSF53474 371 597 1.79E-53 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS36860 4c22cdc8705cf56e5ff0b1679e1a5507 615 Pfam PF00326 Prolyl oligopeptidase family 406 614 4.4E-43 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CU254_RS35190 47decb24c3f6fa26506bef97347481ab 264 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 9 229 7.0E-44 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CU254_RS35190 47decb24c3f6fa26506bef97347481ab 264 Pfam PF13242 HAD-hyrolase-like 180 253 1.3E-22 T 28-03-2018 CU254_RS35190 47decb24c3f6fa26506bef97347481ab 264 PIRSF PIRSF000915 6 257 7.9E-54 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CU254_RS35190 47decb24c3f6fa26506bef97347481ab 264 Pfam PF13344 Haloacid dehalogenase-like hydrolase 9 107 2.3E-24 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CU254_RS35190 47decb24c3f6fa26506bef97347481ab 264 Gene3D G3DSA:3.40.50.1000 73 182 1.6E-31 T 28-03-2018 IPR023214 HAD-like domain CU254_RS35190 47decb24c3f6fa26506bef97347481ab 264 SUPERFAMILY SSF56784 8 254 2.46E-67 T 28-03-2018 IPR023214 HAD-like domain CU254_RS36635 706d97ddd79d8d21acf77000547497fa 659 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 33 85 1.2E-21 T 28-03-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 CU254_RS36635 706d97ddd79d8d21acf77000547497fa 659 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 13 653 50.359 T 28-03-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 CU254_RS36635 706d97ddd79d8d21acf77000547497fa 659 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 28 650 1.5E-288 T 28-03-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 CU254_RS36635 706d97ddd79d8d21acf77000547497fa 659 ProSitePatterns PS00455 Putative AMP-binding domain signature. 267 278 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS36635 706d97ddd79d8d21acf77000547497fa 659 Gene3D G3DSA:3.40.50.980 273 435 5.3E-35 T 28-03-2018 CU254_RS36635 706d97ddd79d8d21acf77000547497fa 659 Gene3D G3DSA:2.30.38.10 436 524 3.4E-14 T 28-03-2018 CU254_RS36635 706d97ddd79d8d21acf77000547497fa 659 Pfam PF13193 AMP-binding enzyme C-terminal domain 540 619 1.2E-26 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS36635 706d97ddd79d8d21acf77000547497fa 659 Pfam PF00501 AMP-binding enzyme 92 531 6.0E-93 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS36635 706d97ddd79d8d21acf77000547497fa 659 Gene3D G3DSA:3.30.300.30 525 637 5.5E-30 T 28-03-2018 CU254_RS36635 706d97ddd79d8d21acf77000547497fa 659 Gene3D G3DSA:3.40.50.980 78 272 4.7E-49 T 28-03-2018 CU254_RS36635 706d97ddd79d8d21acf77000547497fa 659 SUPERFAMILY SSF56801 30 649 2.35E-171 T 28-03-2018 CU254_RS16940 add96b05e5b3c69b5ccc19d06983a255 536 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 309 329 6.6E-7 T 28-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 CU254_RS16940 add96b05e5b3c69b5ccc19d06983a255 536 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 430 446 6.6E-7 T 28-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 CU254_RS16940 add96b05e5b3c69b5ccc19d06983a255 536 PRINTS PR00730 Thermolysin metalloprotease (M4) family signature 365 376 6.6E-7 T 28-03-2018 IPR023612 Peptidase M4 GO:0004222|GO:0006508 CU254_RS16940 add96b05e5b3c69b5ccc19d06983a255 536 Pfam PF03413 Peptidase propeptide and YPEB domain 126 190 2.6E-7 T 28-03-2018 IPR025711 PepSY domain CU254_RS16940 add96b05e5b3c69b5ccc19d06983a255 536 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 216 352 2.1E-27 T 28-03-2018 IPR013856 Peptidase M4 domain GO:0004222 CU254_RS16940 add96b05e5b3c69b5ccc19d06983a255 536 Gene3D G3DSA:1.10.390.10 360 529 1.7E-39 T 28-03-2018 CU254_RS16940 add96b05e5b3c69b5ccc19d06983a255 536 Gene3D G3DSA:3.10.170.10 214 356 3.5E-29 T 28-03-2018 CU254_RS16940 add96b05e5b3c69b5ccc19d06983a255 536 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 362 524 3.8E-36 T 28-03-2018 IPR001570 Peptidase M4, C-terminal GO:0004222 CU254_RS16940 add96b05e5b3c69b5ccc19d06983a255 536 SUPERFAMILY SSF55486 212 524 4.94E-60 T 28-03-2018 CU254_RS29700 f65559113161fcaf4f627e12d8d0a0ff 395 Gene3D G3DSA:2.30.40.10 4 62 1.6E-11 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS29700 f65559113161fcaf4f627e12d8d0a0ff 395 SUPERFAMILY SSF51556 52 358 9.91E-66 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS29700 f65559113161fcaf4f627e12d8d0a0ff 395 SUPERFAMILY SSF51338 349 392 4.99E-9 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS29700 f65559113161fcaf4f627e12d8d0a0ff 395 SUPERFAMILY SSF51338 10 52 4.99E-9 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS29700 f65559113161fcaf4f627e12d8d0a0ff 395 Pfam PF07969 Amidohydrolase family 130 387 5.5E-17 T 28-03-2018 IPR013108 Amidohydrolase 3 CU254_RS29700 f65559113161fcaf4f627e12d8d0a0ff 395 Gene3D G3DSA:2.30.40.10 332 393 7.0E-4 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS29700 f65559113161fcaf4f627e12d8d0a0ff 395 Gene3D G3DSA:3.20.20.140 63 331 2.1E-32 T 28-03-2018 CU254_RS20280 084c7c27ab0da20b024f6441f8e93e0d 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 58 1.3E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS20280 084c7c27ab0da20b024f6441f8e93e0d 198 ProSitePatterns PS01081 TetR-type HTH domain signature. 24 54 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CU254_RS20280 084c7c27ab0da20b024f6441f8e93e0d 198 SUPERFAMILY SSF46689 1 74 1.69E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS20280 084c7c27ab0da20b024f6441f8e93e0d 198 SUPERFAMILY SSF48498 80 190 9.15E-22 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS20280 084c7c27ab0da20b024f6441f8e93e0d 198 Gene3D G3DSA:1.10.357.10 59 196 6.1E-21 T 28-03-2018 CU254_RS20280 084c7c27ab0da20b024f6441f8e93e0d 198 Gene3D G3DSA:1.10.10.60 1 58 3.3E-12 T 28-03-2018 CU254_RS01075 a3758510e569b6cc818ce460cfdfb8c9 270 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 4 97 1.3E-19 T 28-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal CU254_RS01075 a3758510e569b6cc818ce460cfdfb8c9 270 Gene3D G3DSA:3.40.50.720 2 161 2.8E-32 T 28-03-2018 CU254_RS01075 a3758510e569b6cc818ce460cfdfb8c9 270 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 220 242 - T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CU254_RS01075 a3758510e569b6cc818ce460cfdfb8c9 270 SUPERFAMILY SSF51735 4 158 6.81E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS01075 a3758510e569b6cc818ce460cfdfb8c9 270 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 2 264 26.758 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CU254_RS01075 a3758510e569b6cc818ce460cfdfb8c9 270 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 4 264 9.4E-81 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CU254_RS01075 a3758510e569b6cc818ce460cfdfb8c9 270 Gene3D G3DSA:1.10.3730.10 162 269 6.1E-43 T 28-03-2018 CU254_RS01075 a3758510e569b6cc818ce460cfdfb8c9 270 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 160 264 6.8E-38 T 28-03-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 CU254_RS01075 a3758510e569b6cc818ce460cfdfb8c9 270 SUPERFAMILY SSF48179 159 266 9.86E-36 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CU254_RS01075 a3758510e569b6cc818ce460cfdfb8c9 270 PIRSF PIRSF000193 1 267 4.5E-75 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CU254_RS28980 f028befbf635d1e2199fd9e86751a736 492 ProSitePatterns PS00216 Sugar transport proteins signature 1. 80 96 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CU254_RS28980 f028befbf635d1e2199fd9e86751a736 492 SUPERFAMILY SSF103473 262 479 2.09E-68 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS28980 f028befbf635d1e2199fd9e86751a736 492 SUPERFAMILY SSF103473 14 214 2.09E-68 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS28980 f028befbf635d1e2199fd9e86751a736 492 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 26 437 1.2E-76 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CU254_RS28980 f028befbf635d1e2199fd9e86751a736 492 Gene3D G3DSA:1.20.1250.20 273 488 7.7E-27 T 28-03-2018 CU254_RS28980 f028befbf635d1e2199fd9e86751a736 492 Pfam PF07690 Major Facilitator Superfamily 31 425 7.7E-57 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS28980 f028befbf635d1e2199fd9e86751a736 492 PRINTS PR01036 Tetracycline resistance protein TetB signature 89 111 1.8E-6 T 28-03-2018 CU254_RS28980 f028befbf635d1e2199fd9e86751a736 492 PRINTS PR01036 Tetracycline resistance protein TetB signature 152 176 1.8E-6 T 28-03-2018 CU254_RS28980 f028befbf635d1e2199fd9e86751a736 492 PRINTS PR01036 Tetracycline resistance protein TetB signature 29 53 1.8E-6 T 28-03-2018 CU254_RS28980 f028befbf635d1e2199fd9e86751a736 492 Gene3D G3DSA:1.20.1250.20 15 216 1.1E-34 T 28-03-2018 CU254_RS21975 08d538f240c894114ee086d3d3e29fdb 597 Gene3D G3DSA:3.20.20.80 43 506 1.7E-120 T 28-03-2018 CU254_RS21975 08d538f240c894114ee086d3d3e29fdb 597 Pfam PF00128 Alpha amylase, catalytic domain 72 428 5.9E-73 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CU254_RS21975 08d538f240c894114ee086d3d3e29fdb 597 SUPERFAMILY SSF51011 511 592 6.32E-16 T 28-03-2018 CU254_RS21975 08d538f240c894114ee086d3d3e29fdb 597 Gene3D G3DSA:2.60.40.1180 511 592 1.4E-24 T 28-03-2018 CU254_RS21975 08d538f240c894114ee086d3d3e29fdb 597 Pfam PF16657 Maltogenic Amylase, C-terminal domain 507 589 4.0E-21 T 28-03-2018 IPR032091 Maltogenic Amylase, C-terminal CU254_RS21975 08d538f240c894114ee086d3d3e29fdb 597 SUPERFAMILY SSF51445 60 508 1.06E-131 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS21975 08d538f240c894114ee086d3d3e29fdb 597 TIGRFAM TIGR02456 treS_nterm: trehalose synthase 48 592 2.6E-287 T 28-03-2018 IPR012810 Trehalose synthase/alpha-amylase, N-terminal GO:0003824|GO:0005975 KEGG: 00500+5.4.99.16|MetaCyc: PWY-2622 CU254_RS21975 08d538f240c894114ee086d3d3e29fdb 597 SMART SM00642 57 459 1.1E-115 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CU254_RS02790 7f3e71313227904c963a2c84f914b402 460 SUPERFAMILY SSF52743 133 459 4.84E-64 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS02790 7f3e71313227904c963a2c84f914b402 460 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 393 403 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CU254_RS02790 7f3e71313227904c963a2c84f914b402 460 PRINTS PR00723 Subtilisin serine protease family (S8) signature 196 209 1.1E-18 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CU254_RS02790 7f3e71313227904c963a2c84f914b402 460 PRINTS PR00723 Subtilisin serine protease family (S8) signature 152 171 1.1E-18 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CU254_RS02790 7f3e71313227904c963a2c84f914b402 460 PRINTS PR00723 Subtilisin serine protease family (S8) signature 392 408 1.1E-18 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CU254_RS02790 7f3e71313227904c963a2c84f914b402 460 Pfam PF00082 Subtilase family 153 438 1.7E-37 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS02790 7f3e71313227904c963a2c84f914b402 460 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 200 210 - T 28-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site CU254_RS02790 7f3e71313227904c963a2c84f914b402 460 Gene3D G3DSA:3.40.50.200 116 460 1.7E-65 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS02790 7f3e71313227904c963a2c84f914b402 460 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 157 168 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CU254_RS22330 cce9a651bdf7880a16d1ea9d6d9280a3 223 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 66 8.7E-19 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS22330 cce9a651bdf7880a16d1ea9d6d9280a3 223 Gene3D G3DSA:1.10.10.10 8 68 1.8E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS22330 cce9a651bdf7880a16d1ea9d6d9280a3 223 Gene3D G3DSA:1.20.120.530 69 220 4.8E-31 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS22330 cce9a651bdf7880a16d1ea9d6d9280a3 223 SUPERFAMILY SSF48008 79 205 2.33E-25 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS22330 cce9a651bdf7880a16d1ea9d6d9280a3 223 Pfam PF07729 FCD domain 82 201 2.3E-26 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS22330 cce9a651bdf7880a16d1ea9d6d9280a3 223 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 32 46 1.0E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS22330 cce9a651bdf7880a16d1ea9d6d9280a3 223 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 62 1.0E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS22330 cce9a651bdf7880a16d1ea9d6d9280a3 223 SMART SM00895 82 202 2.4E-21 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS22330 cce9a651bdf7880a16d1ea9d6d9280a3 223 SUPERFAMILY SSF46785 11 98 3.58E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS22330 cce9a651bdf7880a16d1ea9d6d9280a3 223 SMART SM00345 14 72 2.9E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS28230 83000c954db000a256cd1895bbb4d476 225 Gene3D G3DSA:1.10.357.10 74 221 2.3E-23 T 28-03-2018 CU254_RS28230 83000c954db000a256cd1895bbb4d476 225 SUPERFAMILY SSF48498 78 214 2.33E-21 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS28230 83000c954db000a256cd1895bbb4d476 225 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 86 211 5.1E-14 T 28-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 CU254_RS28230 83000c954db000a256cd1895bbb4d476 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 2.3E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS28230 83000c954db000a256cd1895bbb4d476 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 2.3E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS28230 83000c954db000a256cd1895bbb4d476 225 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 68 4.7E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS28230 83000c954db000a256cd1895bbb4d476 225 SUPERFAMILY SSF46689 10 73 3.98E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS28230 83000c954db000a256cd1895bbb4d476 225 PRINTS PR00400 Tetracycline repressor protein signature 34 57 6.3E-5 T 28-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 CU254_RS28230 83000c954db000a256cd1895bbb4d476 225 PRINTS PR00400 Tetracycline repressor protein signature 141 160 6.3E-5 T 28-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 CU254_RS28230 83000c954db000a256cd1895bbb4d476 225 PRINTS PR00400 Tetracycline repressor protein signature 85 104 6.3E-5 T 28-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 CU254_RS28230 83000c954db000a256cd1895bbb4d476 225 Gene3D G3DSA:1.10.10.60 3 73 2.7E-19 T 28-03-2018 CU254_RS21920 927190ab6dceae53b3a0aba0f0cfc5aa 566 SUPERFAMILY SSF143975 5 366 1.96E-121 T 28-03-2018 CU254_RS21920 927190ab6dceae53b3a0aba0f0cfc5aa 566 Pfam PF00920 Dehydratase family 34 548 8.5E-181 T 28-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CU254_RS21920 927190ab6dceae53b3a0aba0f0cfc5aa 566 SUPERFAMILY SSF52016 368 553 7.22E-58 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CU254_RS21920 927190ab6dceae53b3a0aba0f0cfc5aa 566 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 117 127 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CU254_RS28760 50828606e7851f4fa0bbc462b9449318 920 Pfam PF01804 Penicillin amidase 138 819 4.3E-100 T 28-03-2018 IPR002692 Penicillin/GL-7-ACA/AHL/aculeacin-A acylase GO:0016787|GO:0017000 CU254_RS28760 50828606e7851f4fa0bbc462b9449318 920 Gene3D G3DSA:1.10.439.10 129 310 2.2E-41 T 28-03-2018 IPR023343 Penicillin amidase type, domain1 GO:0016811 CU254_RS28760 50828606e7851f4fa0bbc462b9449318 920 Gene3D G3DSA:1.10.287.150 311 351 2.6E-8 T 28-03-2018 CU254_RS28760 50828606e7851f4fa0bbc462b9449318 920 SUPERFAMILY SSF56235 394 790 1.16E-79 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CU254_RS28760 50828606e7851f4fa0bbc462b9449318 920 SUPERFAMILY SSF56235 137 344 1.16E-79 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CU254_RS28760 50828606e7851f4fa0bbc462b9449318 920 Gene3D G3DSA:3.60.20.10 402 919 1.1E-56 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CU254_RS21950 0aa8a5546e1c4b8cb082a7b5bceacffd 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 162 2.1E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS21950 0aa8a5546e1c4b8cb082a7b5bceacffd 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 181 2.1E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS21950 0aa8a5546e1c4b8cb082a7b5bceacffd 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 117 133 2.1E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS21950 0aa8a5546e1c4b8cb082a7b5bceacffd 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 70 81 2.1E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS21950 0aa8a5546e1c4b8cb082a7b5bceacffd 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 2.1E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS21950 0aa8a5546e1c4b8cb082a7b5bceacffd 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 162 2.6E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS21950 0aa8a5546e1c4b8cb082a7b5bceacffd 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 123 131 2.6E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS21950 0aa8a5546e1c4b8cb082a7b5bceacffd 273 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 70 81 2.6E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS21950 0aa8a5546e1c4b8cb082a7b5bceacffd 273 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 179 2.1E-4 T 28-03-2018 CU254_RS21950 0aa8a5546e1c4b8cb082a7b5bceacffd 273 SUPERFAMILY SSF51735 1 232 5.16E-67 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS21950 0aa8a5546e1c4b8cb082a7b5bceacffd 273 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 130 158 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS21950 0aa8a5546e1c4b8cb082a7b5bceacffd 273 Gene3D G3DSA:3.40.50.720 2 267 4.2E-68 T 28-03-2018 CU254_RS21950 0aa8a5546e1c4b8cb082a7b5bceacffd 273 Pfam PF00106 short chain dehydrogenase 5 183 1.9E-50 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS08015 16ee63ea9dc5f75f54d09caa9cd55d69 503 SMART SM00382 210 392 5.5E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS08015 16ee63ea9dc5f75f54d09caa9cd55d69 503 Pfam PF01078 Magnesium chelatase, subunit ChlI 190 392 9.4E-83 T 28-03-2018 IPR000523 Magnesium chelatase ChlI domain CU254_RS08015 16ee63ea9dc5f75f54d09caa9cd55d69 503 SUPERFAMILY SSF54211 6 170 1.25E-31 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CU254_RS08015 16ee63ea9dc5f75f54d09caa9cd55d69 503 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 7 498 3.4E-138 T 28-03-2018 IPR004482 Mg chelatase-related protein CU254_RS08015 16ee63ea9dc5f75f54d09caa9cd55d69 503 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 403 498 8.0E-24 T 28-03-2018 IPR025158 Mg chelatase-related protein, C-terminal domain CU254_RS08015 16ee63ea9dc5f75f54d09caa9cd55d69 503 SUPERFAMILY SSF52540 190 498 1.81E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS08015 16ee63ea9dc5f75f54d09caa9cd55d69 503 Gene3D G3DSA:3.30.230.10 2 186 1.8E-37 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CU254_RS08015 16ee63ea9dc5f75f54d09caa9cd55d69 503 Pfam PF13541 Subunit ChlI of Mg-chelatase 21 142 1.8E-36 T 28-03-2018 CU254_RS08015 16ee63ea9dc5f75f54d09caa9cd55d69 503 Gene3D G3DSA:3.40.50.300 187 432 1.3E-23 T 28-03-2018 CU254_RS06635 9c2ebe2c9ac5619aa5acaf05fb81766a 114 Pfam PF12680 SnoaL-like domain 6 101 1.6E-14 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CU254_RS06635 9c2ebe2c9ac5619aa5acaf05fb81766a 114 Gene3D G3DSA:3.10.450.50 1 113 2.0E-21 T 28-03-2018 CU254_RS06635 9c2ebe2c9ac5619aa5acaf05fb81766a 114 SUPERFAMILY SSF54427 3 107 1.84E-19 T 28-03-2018 IPR032710 NTF2-like domain CU254_RS30580 a6758b77fea5a256a1138753fd8ab929 366 Pfam PF02595 Glycerate kinase family 3 360 1.4E-118 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CU254_RS30580 a6758b77fea5a256a1138753fd8ab929 366 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 3 358 1.6E-105 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CU254_RS30580 a6758b77fea5a256a1138753fd8ab929 366 Gene3D G3DSA:3.90.1510.10 42 265 6.4E-77 T 28-03-2018 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 CU254_RS30580 a6758b77fea5a256a1138753fd8ab929 366 PIRSF PIRSF006078 1 363 8.6E-113 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CU254_RS30580 a6758b77fea5a256a1138753fd8ab929 366 SUPERFAMILY SSF110738 2 359 6.54E-107 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CU254_RS06110 bb5c4d15d8367fa1d73542a8e4abfd0c 958 Pfam PF03704 Bacterial transcriptional activator domain 104 243 7.6E-35 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CU254_RS06110 bb5c4d15d8367fa1d73542a8e4abfd0c 958 SUPERFAMILY SSF48452 115 244 3.21E-27 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS06110 bb5c4d15d8367fa1d73542a8e4abfd0c 958 SUPERFAMILY SSF48452 790 939 5.31E-17 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS06110 bb5c4d15d8367fa1d73542a8e4abfd0c 958 SMART SM01043 103 246 2.3E-34 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CU254_RS06110 bb5c4d15d8367fa1d73542a8e4abfd0c 958 Gene3D G3DSA:1.25.40.10 100 276 2.6E-20 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS06110 bb5c4d15d8367fa1d73542a8e4abfd0c 958 Pfam PF00486 Transcriptional regulatory protein, C terminal 26 96 4.5E-8 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS06110 bb5c4d15d8367fa1d73542a8e4abfd0c 958 Gene3D G3DSA:1.10.10.10 2 99 5.0E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS06110 bb5c4d15d8367fa1d73542a8e4abfd0c 958 Gene3D G3DSA:1.25.40.10 792 946 1.0E-19 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS06110 bb5c4d15d8367fa1d73542a8e4abfd0c 958 Gene3D G3DSA:1.10.150.200 690 753 5.0E-8 T 28-03-2018 CU254_RS06110 bb5c4d15d8367fa1d73542a8e4abfd0c 958 PRINTS PR00364 Disease resistance protein signature 452 466 3.9E-9 T 28-03-2018 CU254_RS06110 bb5c4d15d8367fa1d73542a8e4abfd0c 958 PRINTS PR00364 Disease resistance protein signature 290 305 3.9E-9 T 28-03-2018 CU254_RS06110 bb5c4d15d8367fa1d73542a8e4abfd0c 958 PRINTS PR00364 Disease resistance protein signature 367 381 3.9E-9 T 28-03-2018 CU254_RS06110 bb5c4d15d8367fa1d73542a8e4abfd0c 958 SUPERFAMILY SSF46894 5 96 2.83E-14 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS06110 bb5c4d15d8367fa1d73542a8e4abfd0c 958 Pfam PF00931 NB-ARC domain 273 522 6.6E-14 T 28-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 CU254_RS06110 bb5c4d15d8367fa1d73542a8e4abfd0c 958 Gene3D G3DSA:3.30.70.100 754 791 2.1E-5 T 28-03-2018 CU254_RS06110 bb5c4d15d8367fa1d73542a8e4abfd0c 958 SMART SM00382 287 439 0.0025 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS06110 bb5c4d15d8367fa1d73542a8e4abfd0c 958 SUPERFAMILY SSF48452 704 816 1.9E-16 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS06110 bb5c4d15d8367fa1d73542a8e4abfd0c 958 Pfam PF13424 Tetratricopeptide repeat 704 773 7.6E-8 T 28-03-2018 CU254_RS06110 bb5c4d15d8367fa1d73542a8e4abfd0c 958 Gene3D G3DSA:3.40.50.300 277 454 1.1E-11 T 28-03-2018 CU254_RS06110 bb5c4d15d8367fa1d73542a8e4abfd0c 958 SUPERFAMILY SSF52540 252 515 3.86E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS06110 bb5c4d15d8367fa1d73542a8e4abfd0c 958 SMART SM00862 18 96 5.9E-14 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS06110 bb5c4d15d8367fa1d73542a8e4abfd0c 958 SMART SM00028 704 737 12.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS06110 bb5c4d15d8367fa1d73542a8e4abfd0c 958 SMART SM00028 744 777 0.077 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS06110 bb5c4d15d8367fa1d73542a8e4abfd0c 958 SMART SM00028 904 937 95.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS06110 bb5c4d15d8367fa1d73542a8e4abfd0c 958 SMART SM00028 864 897 500.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS06110 bb5c4d15d8367fa1d73542a8e4abfd0c 958 SMART SM00028 784 817 380.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS06110 bb5c4d15d8367fa1d73542a8e4abfd0c 958 SMART SM00028 824 857 0.33 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS23740 ec6e4e39394ed38670f71c95666ef30b 320 SUPERFAMILY SSF160240 230 300 1.57E-8 T 28-03-2018 CU254_RS23740 ec6e4e39394ed38670f71c95666ef30b 320 Gene3D G3DSA:1.20.1510.10 25 220 1.7E-47 T 28-03-2018 CU254_RS23740 ec6e4e39394ed38670f71c95666ef30b 320 SUPERFAMILY SSF161111 26 221 9.02E-49 T 28-03-2018 CU254_RS23740 ec6e4e39394ed38670f71c95666ef30b 320 Gene3D G3DSA:3.30.70.1350 228 301 4.4E-10 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CU254_RS23740 ec6e4e39394ed38670f71c95666ef30b 320 Pfam PF01545 Cation efflux family 29 219 9.5E-42 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CU254_RS23740 ec6e4e39394ed38670f71c95666ef30b 320 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 26 300 2.9E-74 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CU254_RS16550 b0968252bdbdc9ac038fdbb0a1663688 306 SUPERFAMILY SSF52402 160 301 2.26E-35 T 28-03-2018 CU254_RS16550 b0968252bdbdc9ac038fdbb0a1663688 306 PRINTS PR01438 Universal stress protein signature 258 270 3.5E-15 T 28-03-2018 IPR006015 Universal stress protein A CU254_RS16550 b0968252bdbdc9ac038fdbb0a1663688 306 PRINTS PR01438 Universal stress protein signature 159 177 3.5E-15 T 28-03-2018 IPR006015 Universal stress protein A CU254_RS16550 b0968252bdbdc9ac038fdbb0a1663688 306 PRINTS PR01438 Universal stress protein signature 276 298 3.5E-15 T 28-03-2018 IPR006015 Universal stress protein A CU254_RS16550 b0968252bdbdc9ac038fdbb0a1663688 306 SUPERFAMILY SSF52402 11 155 2.01E-27 T 28-03-2018 CU254_RS16550 b0968252bdbdc9ac038fdbb0a1663688 306 Gene3D G3DSA:3.40.50.620 159 300 2.0E-39 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS16550 b0968252bdbdc9ac038fdbb0a1663688 306 Pfam PF00582 Universal stress protein family 11 153 6.0E-18 T 28-03-2018 IPR006016 UspA GO:0006950 CU254_RS16550 b0968252bdbdc9ac038fdbb0a1663688 306 Pfam PF00582 Universal stress protein family 160 298 3.0E-30 T 28-03-2018 IPR006016 UspA GO:0006950 CU254_RS16550 b0968252bdbdc9ac038fdbb0a1663688 306 Gene3D G3DSA:3.40.50.620 2 158 7.7E-27 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS23955 336b76092ac2e77c733af2f02f0ae0ef 256 Gene3D G3DSA:3.40.1080.10 1 251 3.2E-32 T 28-03-2018 CU254_RS23955 336b76092ac2e77c733af2f02f0ae0ef 256 Pfam PF01144 Coenzyme A transferase 95 212 5.1E-9 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CU254_RS23955 336b76092ac2e77c733af2f02f0ae0ef 256 SMART SM00882 9 213 4.0E-5 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CU254_RS23955 336b76092ac2e77c733af2f02f0ae0ef 256 SUPERFAMILY SSF100950 5 249 4.27E-46 T 28-03-2018 CU254_RS00105 ec7ed9b505aeb0e24a9c507613cbc41a 192 Gene3D G3DSA:1.10.357.10 73 191 2.2E-22 T 28-03-2018 CU254_RS00105 ec7ed9b505aeb0e24a9c507613cbc41a 192 SUPERFAMILY SSF48498 85 178 1.56E-18 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS00105 ec7ed9b505aeb0e24a9c507613cbc41a 192 Gene3D G3DSA:1.10.10.60 2 51 8.5E-15 T 28-03-2018 CU254_RS00105 ec7ed9b505aeb0e24a9c507613cbc41a 192 Gene3D G3DSA:1.10.10.60 52 72 8.0E-5 T 28-03-2018 CU254_RS00105 ec7ed9b505aeb0e24a9c507613cbc41a 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 3.6E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS00105 ec7ed9b505aeb0e24a9c507613cbc41a 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 3.6E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS00105 ec7ed9b505aeb0e24a9c507613cbc41a 192 SUPERFAMILY SSF46689 6 79 4.16E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS00105 ec7ed9b505aeb0e24a9c507613cbc41a 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 64 1.7E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS00105 ec7ed9b505aeb0e24a9c507613cbc41a 192 Pfam PF13305 WHG domain 92 173 3.0E-13 T 28-03-2018 IPR025996 WHG domain CU254_RS00780 f4408f109025da6ca4343107b082195c 285 PRINTS PR00412 Epoxide hydrolase signature 94 107 3.6E-11 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS00780 f4408f109025da6ca4343107b082195c 285 PRINTS PR00412 Epoxide hydrolase signature 108 121 3.6E-11 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS00780 f4408f109025da6ca4343107b082195c 285 PRINTS PR00412 Epoxide hydrolase signature 260 282 3.6E-11 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS00780 f4408f109025da6ca4343107b082195c 285 PRINTS PR00412 Epoxide hydrolase signature 31 49 3.6E-11 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS00780 f4408f109025da6ca4343107b082195c 285 PRINTS PR00111 Alpha/beta hydrolase fold signature 108 121 3.5E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS00780 f4408f109025da6ca4343107b082195c 285 PRINTS PR00111 Alpha/beta hydrolase fold signature 94 107 3.5E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS00780 f4408f109025da6ca4343107b082195c 285 PRINTS PR00111 Alpha/beta hydrolase fold signature 50 65 3.5E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS00780 f4408f109025da6ca4343107b082195c 285 Pfam PF00561 alpha/beta hydrolase fold 25 144 3.5E-22 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS00780 f4408f109025da6ca4343107b082195c 285 Gene3D G3DSA:3.40.50.1820 1 285 9.6E-58 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS00780 f4408f109025da6ca4343107b082195c 285 SUPERFAMILY SSF53474 5 285 4.85E-80 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS23140 321aa6bc44fa324b49f2025dc22bfba3 415 Gene3D G3DSA:3.30.830.10 233 414 9.8E-7 T 28-03-2018 CU254_RS23140 321aa6bc44fa324b49f2025dc22bfba3 415 Pfam PF05193 Peptidase M16 inactive domain 169 346 2.9E-9 T 28-03-2018 IPR007863 Peptidase M16, C-terminal CU254_RS23140 321aa6bc44fa324b49f2025dc22bfba3 415 SUPERFAMILY SSF63411 240 409 1.27E-9 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CU254_RS23140 321aa6bc44fa324b49f2025dc22bfba3 415 Gene3D G3DSA:3.30.830.10 2 222 2.2E-40 T 28-03-2018 CU254_RS23140 321aa6bc44fa324b49f2025dc22bfba3 415 Pfam PF00675 Insulinase (Peptidase family M16) 15 128 2.0E-16 T 28-03-2018 IPR011765 Peptidase M16, N-terminal CU254_RS23140 321aa6bc44fa324b49f2025dc22bfba3 415 SUPERFAMILY SSF63411 4 220 3.12E-35 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CU254_RS10345 595f1156f83bce10b963f255124b0489 200 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 19 197 33.579 T 28-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CU254_RS10345 595f1156f83bce10b963f255124b0489 200 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 76 92 - T 28-03-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CU254_RS10345 595f1156f83bce10b963f255124b0489 200 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 25 195 9.6E-57 T 28-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CU254_RS10345 595f1156f83bce10b963f255124b0489 200 Gene3D G3DSA:1.10.286.10 21 61 1.3E-11 T 28-03-2018 CU254_RS10345 595f1156f83bce10b963f255124b0489 200 Pfam PF01227 GTP cyclohydrolase I 24 195 1.4E-61 T 28-03-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CU254_RS10345 595f1156f83bce10b963f255124b0489 200 SUPERFAMILY SSF55620 10 196 1.11E-67 T 28-03-2018 CU254_RS10345 595f1156f83bce10b963f255124b0489 200 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 124 134 - T 28-03-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CU254_RS10345 595f1156f83bce10b963f255124b0489 200 Gene3D G3DSA:3.30.1130.10 66 199 1.5E-53 T 28-03-2018 CU254_RS29815 08e549b9abe082477b5e1e8dc5bb94bd 403 Pfam PF02371 Transposase IS116/IS110/IS902 family 271 356 7.6E-23 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CU254_RS29815 08e549b9abe082477b5e1e8dc5bb94bd 403 Gene3D G3DSA:3.30.420.40 4 323 5.2E-5 T 28-03-2018 CU254_RS29815 08e549b9abe082477b5e1e8dc5bb94bd 403 Pfam PF01548 Transposase 9 163 1.1E-43 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CU254_RS25740 08e549b9abe082477b5e1e8dc5bb94bd 403 Pfam PF02371 Transposase IS116/IS110/IS902 family 271 356 7.6E-23 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CU254_RS25740 08e549b9abe082477b5e1e8dc5bb94bd 403 Gene3D G3DSA:3.30.420.40 4 323 5.2E-5 T 28-03-2018 CU254_RS25740 08e549b9abe082477b5e1e8dc5bb94bd 403 Pfam PF01548 Transposase 9 163 1.1E-43 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CU254_RS25330 696fb3932097b425ad092fe02595d994 307 Gene3D G3DSA:3.40.190.10 26 190 6.2E-29 T 28-03-2018 CU254_RS25330 696fb3932097b425ad092fe02595d994 307 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 68 290 7.5E-50 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CU254_RS25330 696fb3932097b425ad092fe02595d994 307 SUPERFAMILY SSF53850 12 24 3.15E-54 T 28-03-2018 CU254_RS25330 696fb3932097b425ad092fe02595d994 307 SUPERFAMILY SSF53850 57 293 3.15E-54 T 28-03-2018 CU254_RS25330 696fb3932097b425ad092fe02595d994 307 SMART SM00062 67 294 3.4E-39 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CU254_RS25330 696fb3932097b425ad092fe02595d994 307 Gene3D G3DSA:3.40.190.10 191 307 7.8E-15 T 28-03-2018 CU254_RS38030 05cf0f357136486dc2e9b559a5324fc2 318 Pfam PF00107 Zinc-binding dehydrogenase 153 277 5.5E-12 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CU254_RS38030 05cf0f357136486dc2e9b559a5324fc2 318 SUPERFAMILY SSF51735 121 281 3.86E-23 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS38030 05cf0f357136486dc2e9b559a5324fc2 318 SUPERFAMILY SSF50129 14 153 2.11E-13 T 28-03-2018 IPR011032 GroES-like CU254_RS38030 05cf0f357136486dc2e9b559a5324fc2 318 Gene3D G3DSA:3.90.180.10 1 148 7.0E-13 T 28-03-2018 CU254_RS38030 05cf0f357136486dc2e9b559a5324fc2 318 Gene3D G3DSA:3.40.50.720 149 267 3.3E-21 T 28-03-2018 CU254_RS33175 8a09200b85a4da969308154baa11a5df 380 Pfam PF13377 Periplasmic binding protein-like domain 219 380 3.2E-32 T 28-03-2018 CU254_RS33175 8a09200b85a4da969308154baa11a5df 380 Gene3D G3DSA:3.40.50.2300 99 226 7.8E-32 T 28-03-2018 CU254_RS33175 8a09200b85a4da969308154baa11a5df 380 ProSitePatterns PS00356 LacI-type HTH domain signature. 50 68 - T 28-03-2018 CU254_RS33175 8a09200b85a4da969308154baa11a5df 380 Gene3D G3DSA:3.40.50.2300 227 380 1.3E-42 T 28-03-2018 CU254_RS33175 8a09200b85a4da969308154baa11a5df 380 SUPERFAMILY SSF47413 47 105 1.69E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS33175 8a09200b85a4da969308154baa11a5df 380 Gene3D G3DSA:1.10.260.40 46 98 6.3E-22 T 28-03-2018 CU254_RS33175 8a09200b85a4da969308154baa11a5df 380 Pfam PF00356 Bacterial regulatory proteins, lacI family 49 94 6.6E-17 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CU254_RS33175 8a09200b85a4da969308154baa11a5df 380 SUPERFAMILY SSF53822 108 377 4.53E-53 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CU254_RS33175 8a09200b85a4da969308154baa11a5df 380 SMART SM00354 47 117 8.4E-26 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CU254_RS18370 1eb9a5baabf30e45ef88e790bd93e539 402 Gene3D G3DSA:1.25.40.10 205 399 4.3E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS18370 1eb9a5baabf30e45ef88e790bd93e539 402 SUPERFAMILY SSF88946 6 82 1.22E-11 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS18370 1eb9a5baabf30e45ef88e790bd93e539 402 Gene3D G3DSA:1.10.10.10 76 161 1.0E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS18370 1eb9a5baabf30e45ef88e790bd93e539 402 Gene3D G3DSA:1.10.1740.10 3 75 3.7E-14 T 28-03-2018 CU254_RS18370 1eb9a5baabf30e45ef88e790bd93e539 402 SUPERFAMILY SSF88659 100 160 1.81E-10 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS18370 1eb9a5baabf30e45ef88e790bd93e539 402 Pfam PF04542 Sigma-70 region 2 11 77 2.7E-9 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS18370 1eb9a5baabf30e45ef88e790bd93e539 402 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 17 160 1.7E-14 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS18370 1eb9a5baabf30e45ef88e790bd93e539 402 Pfam PF08281 Sigma-70, region 4 108 158 5.9E-7 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS11430 4ba85e5c4eb0fab24aa39b48c3fe79ad 143 PIRSF PIRSF001399 1 143 3.0E-56 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CU254_RS11430 4ba85e5c4eb0fab24aa39b48c3fe79ad 143 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 4 139 5.0E-47 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CU254_RS11430 4ba85e5c4eb0fab24aa39b48c3fe79ad 143 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 4 139 7.7E-56 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CU254_RS11430 4ba85e5c4eb0fab24aa39b48c3fe79ad 143 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 143 60.005 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CU254_RS11430 4ba85e5c4eb0fab24aa39b48c3fe79ad 143 Pfam PF01220 Dehydroquinase class II 4 138 1.1E-52 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CU254_RS11430 4ba85e5c4eb0fab24aa39b48c3fe79ad 143 Gene3D G3DSA:3.40.50.9100 1 143 4.3E-56 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CU254_RS11430 4ba85e5c4eb0fab24aa39b48c3fe79ad 143 SUPERFAMILY SSF52304 2 140 2.09E-53 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CU254_RS00955 ede5c9915cb5ed3413e21ce5c83d51b8 314 SUPERFAMILY SSF46785 1 60 3.11E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS00955 ede5c9915cb5ed3413e21ce5c83d51b8 314 Gene3D G3DSA:1.10.10.10 1 65 7.4E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS00955 ede5c9915cb5ed3413e21ce5c83d51b8 314 PIRSF PIRSF016838 1 313 1.7E-20 T 28-03-2018 IPR028349 Protein PafC CU254_RS00955 ede5c9915cb5ed3413e21ce5c83d51b8 314 Pfam PF13280 WYL domain 140 304 2.4E-22 T 28-03-2018 IPR026881 WYL domain CU254_RS00955 ede5c9915cb5ed3413e21ce5c83d51b8 314 Pfam PF08279 HTH domain 6 61 2.0E-15 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 CU254_RS34375 676f19847f1f6298b62b93c388d5f9be 311 SUPERFAMILY SSF53335 88 308 9.87E-45 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS34375 676f19847f1f6298b62b93c388d5f9be 311 SUPERFAMILY SSF46785 1 67 5.19E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS34375 676f19847f1f6298b62b93c388d5f9be 311 Pfam PF00891 O-methyltransferase 87 291 6.6E-42 T 28-03-2018 IPR001077 O-methyltransferase, family 2 GO:0008171 CU254_RS34375 676f19847f1f6298b62b93c388d5f9be 311 Gene3D G3DSA:1.10.10.10 1 60 8.5E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS34375 676f19847f1f6298b62b93c388d5f9be 311 PIRSF PIRSF005739 1 308 8.0E-35 T 28-03-2018 IPR016461 O-methyltransferase COMT-type GO:0008168 CU254_RS34375 676f19847f1f6298b62b93c388d5f9be 311 Gene3D G3DSA:3.40.50.150 66 311 3.7E-42 T 28-03-2018 CU254_RS25525 c480c4ff463c76242dcca25158b0a97e 409 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 351 360 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CU254_RS25525 c480c4ff463c76242dcca25158b0a97e 409 Pfam PF00067 Cytochrome P450 281 376 7.4E-15 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS25525 c480c4ff463c76242dcca25158b0a97e 409 SUPERFAMILY SSF48264 21 408 3.54E-63 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS25525 c480c4ff463c76242dcca25158b0a97e 409 PRINTS PR00359 B-class P450 signature 349 358 2.2E-19 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS25525 c480c4ff463c76242dcca25158b0a97e 409 PRINTS PR00359 B-class P450 signature 132 148 2.2E-19 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS25525 c480c4ff463c76242dcca25158b0a97e 409 PRINTS PR00359 B-class P450 signature 149 164 2.2E-19 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS25525 c480c4ff463c76242dcca25158b0a97e 409 PRINTS PR00359 B-class P450 signature 300 327 2.2E-19 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS25525 c480c4ff463c76242dcca25158b0a97e 409 PRINTS PR00359 B-class P450 signature 282 293 2.2E-19 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS25525 c480c4ff463c76242dcca25158b0a97e 409 PRINTS PR00359 B-class P450 signature 200 222 2.2E-19 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS25525 c480c4ff463c76242dcca25158b0a97e 409 PRINTS PR00359 B-class P450 signature 328 343 2.2E-19 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS25525 c480c4ff463c76242dcca25158b0a97e 409 Gene3D G3DSA:1.10.630.10 2 409 9.5E-48 T 28-03-2018 CU254_RS08555 9ae0e5334374933cba91f5feaaabd1ca 81 SUPERFAMILY SSF47336 3 79 4.06E-21 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS08555 9ae0e5334374933cba91f5feaaabd1ca 81 Hamap MF_01217 Acyl carrier protein [acpP]. 6 80 17.443 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CU254_RS08555 9ae0e5334374933cba91f5feaaabd1ca 81 Pfam PF00550 Phosphopantetheine attachment site 11 76 8.1E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS08555 9ae0e5334374933cba91f5feaaabd1ca 81 Gene3D G3DSA:1.10.1200.10 1 81 4.6E-22 T 28-03-2018 CU254_RS08555 9ae0e5334374933cba91f5feaaabd1ca 81 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 37 76 2.0E-12 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CU254_RS12760 100e26ac180e1d8104ef9816d446c74f 226 Pfam PF07729 FCD domain 96 214 7.1E-19 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS12760 100e26ac180e1d8104ef9816d446c74f 226 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 61 1.1E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS12760 100e26ac180e1d8104ef9816d446c74f 226 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 31 45 1.1E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS12760 100e26ac180e1d8104ef9816d446c74f 226 SUPERFAMILY SSF48008 96 220 1.8E-17 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS12760 100e26ac180e1d8104ef9816d446c74f 226 Gene3D G3DSA:1.10.10.10 5 73 1.4E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS12760 100e26ac180e1d8104ef9816d446c74f 226 Gene3D G3DSA:1.20.120.530 77 226 2.7E-24 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS12760 100e26ac180e1d8104ef9816d446c74f 226 SUPERFAMILY SSF46785 10 75 2.28E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS12760 100e26ac180e1d8104ef9816d446c74f 226 SMART SM00345 12 71 3.5E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS12760 100e26ac180e1d8104ef9816d446c74f 226 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 70 8.9E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS12760 100e26ac180e1d8104ef9816d446c74f 226 SMART SM00895 96 214 2.1E-15 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS19000 12a8c5b9e831fca243dec8a372a44961 234 SUPERFAMILY SSF53955 39 110 1.88E-25 T 28-03-2018 IPR023346 Lysozyme-like domain CU254_RS19000 12a8c5b9e831fca243dec8a372a44961 234 Pfam PF06737 Transglycosylase-like domain 40 107 1.2E-20 T 28-03-2018 IPR010618 Transglycosylase-like CU254_RS19000 12a8c5b9e831fca243dec8a372a44961 234 SUPERFAMILY SSF47090 160 226 1.44E-9 T 28-03-2018 IPR002477 Peptidoglycan binding-like CU254_RS19000 12a8c5b9e831fca243dec8a372a44961 234 Pfam PF01471 Putative peptidoglycan binding domain 175 226 1.0E-7 T 28-03-2018 IPR002477 Peptidoglycan binding-like CU254_RS19000 12a8c5b9e831fca243dec8a372a44961 234 Gene3D G3DSA:1.10.530.10 3 115 2.5E-19 T 28-03-2018 CU254_RS19000 12a8c5b9e831fca243dec8a372a44961 234 Gene3D G3DSA:1.10.101.10 164 230 2.5E-10 T 28-03-2018 IPR002477 Peptidoglycan binding-like CU254_RS25080 376931162737c1919021a759ab6fed3a 123 Gene3D G3DSA:1.10.10.10 3 123 8.2E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS25080 376931162737c1919021a759ab6fed3a 123 SUPERFAMILY SSF46785 4 115 2.88E-33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS25080 376931162737c1919021a759ab6fed3a 123 Pfam PF01638 HxlR-like helix-turn-helix 19 106 1.5E-27 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type CU254_RS23170 e166e7f45d106a193f0bbad8231c8799 142 Pfam PF00196 Bacterial regulatory proteins, luxR family 80 135 3.8E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS23170 e166e7f45d106a193f0bbad8231c8799 142 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 81 95 5.7E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS23170 e166e7f45d106a193f0bbad8231c8799 142 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 95 111 5.7E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS23170 e166e7f45d106a193f0bbad8231c8799 142 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 111 123 5.7E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS23170 e166e7f45d106a193f0bbad8231c8799 142 SUPERFAMILY SSF46894 71 141 1.22E-18 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS23170 e166e7f45d106a193f0bbad8231c8799 142 Gene3D G3DSA:1.10.10.10 28 142 4.7E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS23170 e166e7f45d106a193f0bbad8231c8799 142 SMART SM00421 78 135 1.9E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS30535 90882d48a52153f4660230dfa5e16d63 305 Pfam PF00480 ROK family 6 293 5.9E-46 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CU254_RS30535 90882d48a52153f4660230dfa5e16d63 305 Gene3D G3DSA:3.30.420.40 2 125 2.2E-24 T 28-03-2018 CU254_RS30535 90882d48a52153f4660230dfa5e16d63 305 SUPERFAMILY SSF53067 5 294 3.6E-52 T 28-03-2018 CU254_RS30535 90882d48a52153f4660230dfa5e16d63 305 Gene3D G3DSA:3.30.420.40 126 295 2.3E-38 T 28-03-2018 CU254_RS30535 90882d48a52153f4660230dfa5e16d63 305 ProSitePatterns PS01125 ROK family signature. 133 160 - T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CU254_RS25320 a7a85a4ad74538a6b8f9a26e9d9b4b17 250 PIRSF PIRSF039085 1 250 1.4E-115 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CU254_RS25320 a7a85a4ad74538a6b8f9a26e9d9b4b17 250 Pfam PF00005 ABC transporter 17 175 1.5E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS25320 a7a85a4ad74538a6b8f9a26e9d9b4b17 250 Gene3D G3DSA:3.40.50.300 1 250 2.8E-71 T 28-03-2018 CU254_RS25320 a7a85a4ad74538a6b8f9a26e9d9b4b17 250 SMART SM00382 26 223 9.5E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS25320 a7a85a4ad74538a6b8f9a26e9d9b4b17 250 SUPERFAMILY SSF52540 1 245 7.55E-76 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS25320 a7a85a4ad74538a6b8f9a26e9d9b4b17 250 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS29465 b4c7fc85dcd8f8461cbec1d99ca968fd 778 PIRSF PIRSF036389 8 755 4.2E-155 T 28-03-2018 IPR012368 Oxidoreductase molybdopterin-binding subunit, IorB-related CU254_RS29465 b4c7fc85dcd8f8461cbec1d99ca968fd 778 Gene3D G3DSA:3.30.365.10 604 753 3.5E-27 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CU254_RS29465 b4c7fc85dcd8f8461cbec1d99ca968fd 778 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 345 444 1.0E-15 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CU254_RS29465 b4c7fc85dcd8f8461cbec1d99ca968fd 778 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 639 696 2.5E-7 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CU254_RS29465 b4c7fc85dcd8f8461cbec1d99ca968fd 778 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 74 207 4.1E-16 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CU254_RS29465 b4c7fc85dcd8f8461cbec1d99ca968fd 778 Gene3D G3DSA:3.30.365.10 341 436 2.9E-19 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CU254_RS29465 b4c7fc85dcd8f8461cbec1d99ca968fd 778 Gene3D G3DSA:3.30.365.10 437 603 7.5E-27 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CU254_RS29465 b4c7fc85dcd8f8461cbec1d99ca968fd 778 SUPERFAMILY SSF56003 17 242 1.96E-28 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CU254_RS29465 b4c7fc85dcd8f8461cbec1d99ca968fd 778 SUPERFAMILY SSF56003 344 750 5.0E-77 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CU254_RS29465 b4c7fc85dcd8f8461cbec1d99ca968fd 778 Gene3D G3DSA:3.90.1170.50 221 336 9.4E-17 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CU254_RS29465 b4c7fc85dcd8f8461cbec1d99ca968fd 778 Gene3D G3DSA:3.30.365.10 63 220 3.8E-33 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CU254_RS29465 b4c7fc85dcd8f8461cbec1d99ca968fd 778 SUPERFAMILY SSF54665 209 313 4.97E-17 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CU254_RS29465 b4c7fc85dcd8f8461cbec1d99ca968fd 778 SMART SM01008 235 314 2.1E-4 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CU254_RS17005 4ee4d9c2553a92daf9b274b727e808f2 296 Pfam PF12833 Helix-turn-helix domain 217 295 5.9E-24 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS17005 4ee4d9c2553a92daf9b274b727e808f2 296 SMART SM00342 211 294 3.6E-34 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS17005 4ee4d9c2553a92daf9b274b727e808f2 296 SUPERFAMILY SSF46689 247 295 7.17E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS17005 4ee4d9c2553a92daf9b274b727e808f2 296 SUPERFAMILY SSF46689 195 245 1.25E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS17005 4ee4d9c2553a92daf9b274b727e808f2 296 Gene3D G3DSA:1.10.10.60 252 295 4.8E-15 T 28-03-2018 CU254_RS17005 4ee4d9c2553a92daf9b274b727e808f2 296 Gene3D G3DSA:1.10.10.60 201 251 1.8E-14 T 28-03-2018 CU254_RS11850 04719ec47e11e7f2d0b1df03535d6d40 180 PIRSF PIRSF016573 23 178 2.2E-49 T 28-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 CU254_RS11850 04719ec47e11e7f2d0b1df03535d6d40 180 PIRSF PIRSF016573 8 35 33.0 T 28-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 CU254_RS11850 04719ec47e11e7f2d0b1df03535d6d40 180 SUPERFAMILY SSF55486 36 164 1.27E-23 T 28-03-2018 CU254_RS11850 04719ec47e11e7f2d0b1df03535d6d40 180 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 100 124 7.8E-29 T 28-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 CU254_RS11850 04719ec47e11e7f2d0b1df03535d6d40 180 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 152 166 7.8E-29 T 28-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 CU254_RS11850 04719ec47e11e7f2d0b1df03535d6d40 180 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 125 149 7.8E-29 T 28-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 CU254_RS11850 04719ec47e11e7f2d0b1df03535d6d40 180 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 42 68 7.8E-29 T 28-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 CU254_RS11850 04719ec47e11e7f2d0b1df03535d6d40 180 ProDom PD016028 PROTEASE METALLOPROTEASE EXTRACELLULAR NEUTRAL SMALL METAL-BINDING ZINC HYDROLASE SNAPALYSIN ZYMOGEN 46 167 1.0E-30 T 28-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 CU254_RS11850 04719ec47e11e7f2d0b1df03535d6d40 180 Gene3D G3DSA:3.40.390.10 35 167 1.8E-20 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CU254_RS11850 04719ec47e11e7f2d0b1df03535d6d40 180 Pfam PF02031 Streptomyces extracellular neutral proteinase (M7) family 35 167 7.3E-45 T 28-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 CU254_RS24535 fb8b6a463e27e9b5bf2dbd983a5fffe7 423 Pfam PF01593 Flavin containing amine oxidoreductase 16 285 3.5E-20 T 28-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 CU254_RS24535 fb8b6a463e27e9b5bf2dbd983a5fffe7 423 Gene3D G3DSA:3.90.660.20 38 388 1.7E-46 T 28-03-2018 CU254_RS24535 fb8b6a463e27e9b5bf2dbd983a5fffe7 423 SUPERFAMILY SSF51905 388 417 1.65E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS24535 fb8b6a463e27e9b5bf2dbd983a5fffe7 423 SUPERFAMILY SSF51905 8 307 1.65E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS00710 e7db3a3ac8af8c6768901090232dc41a 407 Gene3D G3DSA:3.50.50.60 2 127 2.5E-19 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS00710 e7db3a3ac8af8c6768901090232dc41a 407 SUPERFAMILY SSF55424 310 403 1.65E-24 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CU254_RS00710 e7db3a3ac8af8c6768901090232dc41a 407 Gene3D G3DSA:3.50.50.60 154 314 4.2E-34 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS00710 e7db3a3ac8af8c6768901090232dc41a 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 275 1.8E-28 T 28-03-2018 CU254_RS00710 e7db3a3ac8af8c6768901090232dc41a 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 101 119 1.8E-28 T 28-03-2018 CU254_RS00710 e7db3a3ac8af8c6768901090232dc41a 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 1.8E-28 T 28-03-2018 CU254_RS00710 e7db3a3ac8af8c6768901090232dc41a 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 228 244 1.8E-28 T 28-03-2018 CU254_RS00710 e7db3a3ac8af8c6768901090232dc41a 407 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 146 164 1.8E-28 T 28-03-2018 CU254_RS00710 e7db3a3ac8af8c6768901090232dc41a 407 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 298 6.2E-64 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS00710 e7db3a3ac8af8c6768901090232dc41a 407 Gene3D G3DSA:3.50.50.60 128 153 1.1E-10 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS00710 e7db3a3ac8af8c6768901090232dc41a 407 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 146 171 7.7E-15 T 28-03-2018 CU254_RS00710 e7db3a3ac8af8c6768901090232dc41a 407 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 229 243 7.7E-15 T 28-03-2018 CU254_RS00710 e7db3a3ac8af8c6768901090232dc41a 407 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 7.7E-15 T 28-03-2018 CU254_RS00710 e7db3a3ac8af8c6768901090232dc41a 407 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 268 275 7.7E-15 T 28-03-2018 CU254_RS00710 e7db3a3ac8af8c6768901090232dc41a 407 SUPERFAMILY SSF51905 190 331 2.78E-49 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS00710 e7db3a3ac8af8c6768901090232dc41a 407 SUPERFAMILY SSF51905 5 163 2.78E-49 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS00710 e7db3a3ac8af8c6768901090232dc41a 407 Gene3D G3DSA:3.30.390.30 315 407 4.9E-24 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CU254_RS00710 e7db3a3ac8af8c6768901090232dc41a 407 Pfam PF14759 Reductase C-terminal 317 399 2.0E-23 T 28-03-2018 IPR028202 Reductase, C-terminal CU254_RS19975 bec6d66b86785965ba4d787f0b6595b7 413 SUPERFAMILY SSF51905 6 222 2.59E-35 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS19975 bec6d66b86785965ba4d787f0b6595b7 413 Gene3D G3DSA:3.50.50.60 161 182 0.019 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS19975 bec6d66b86785965ba4d787f0b6595b7 413 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 9 196 7.1E-27 T 28-03-2018 CU254_RS19975 bec6d66b86785965ba4d787f0b6595b7 413 Gene3D G3DSA:3.50.50.60 183 412 9.3E-14 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS19975 bec6d66b86785965ba4d787f0b6595b7 413 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 128 137 8.4E-9 T 28-03-2018 CU254_RS19975 bec6d66b86785965ba4d787f0b6595b7 413 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 8.4E-9 T 28-03-2018 CU254_RS19975 bec6d66b86785965ba4d787f0b6595b7 413 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 168 193 8.4E-9 T 28-03-2018 CU254_RS19975 bec6d66b86785965ba4d787f0b6595b7 413 Gene3D G3DSA:3.50.50.60 1 160 4.8E-32 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS19975 bec6d66b86785965ba4d787f0b6595b7 413 SUPERFAMILY SSF51905 297 405 4.27E-5 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS19975 bec6d66b86785965ba4d787f0b6595b7 413 SUPERFAMILY SSF51905 169 249 4.27E-5 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS23900 049e521c00c029be5e7255c697a17975 252 Gene3D G3DSA:3.90.226.10 1 252 5.4E-52 T 28-03-2018 CU254_RS23900 049e521c00c029be5e7255c697a17975 252 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 209 1.7E-36 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CU254_RS23900 049e521c00c029be5e7255c697a17975 252 SUPERFAMILY SSF52096 7 249 7.18E-58 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS26715 7efdbcbed8add21301c3751bb99f5f8f 421 Gene3D G3DSA:3.40.50.1100 99 206 5.7E-21 T 28-03-2018 CU254_RS26715 7efdbcbed8add21301c3751bb99f5f8f 421 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 89 389 2.7E-67 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CU254_RS26715 7efdbcbed8add21301c3751bb99f5f8f 421 TIGRFAM TIGR00260 thrC: threonine synthase 67 395 1.5E-84 T 28-03-2018 IPR004450 Threonine synthase-like CU254_RS26715 7efdbcbed8add21301c3751bb99f5f8f 421 SUPERFAMILY SSF53686 25 415 5.37E-83 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CU254_RS26715 7efdbcbed8add21301c3751bb99f5f8f 421 Gene3D G3DSA:3.40.50.1100 207 406 5.7E-42 T 28-03-2018 CU254_RS30010 9c5934b67e5aec2c7e87d879b050e198 322 Gene3D G3DSA:3.10.129.10 211 322 6.1E-7 T 28-03-2018 CU254_RS30010 9c5934b67e5aec2c7e87d879b050e198 322 Pfam PF03756 A-factor biosynthesis hotdog domain 37 173 2.7E-26 T 28-03-2018 IPR005509 A-factor biosynthesis hotdog domain CU254_RS30010 9c5934b67e5aec2c7e87d879b050e198 322 Pfam PF03756 A-factor biosynthesis hotdog domain 204 318 9.3E-17 T 28-03-2018 IPR005509 A-factor biosynthesis hotdog domain CU254_RS16625 f48adc24a79e17f61acf84bf0dc9d736 520 Pfam PF01565 FAD binding domain 93 231 5.5E-33 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CU254_RS16625 f48adc24a79e17f61acf84bf0dc9d736 520 Gene3D G3DSA:1.10.45.10 467 505 4.1E-8 T 28-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CU254_RS16625 f48adc24a79e17f61acf84bf0dc9d736 520 Pfam PF02913 FAD linked oxidases, C-terminal domain 268 505 4.6E-28 T 28-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CU254_RS16625 f48adc24a79e17f61acf84bf0dc9d736 520 SUPERFAMILY SSF56176 58 268 2.62E-50 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CU254_RS16625 f48adc24a79e17f61acf84bf0dc9d736 520 Gene3D G3DSA:3.30.43.10 33 146 2.3E-15 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CU254_RS16625 f48adc24a79e17f61acf84bf0dc9d736 520 SUPERFAMILY SSF55103 245 509 3.01E-31 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CU254_RS16625 f48adc24a79e17f61acf84bf0dc9d736 520 Gene3D G3DSA:3.30.465.10 148 286 9.4E-35 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CU254_RS16950 dfbc5f577f0bcd89b7126d73c4b08e58 129 Gene3D G3DSA:3.30.1330.40 4 128 1.2E-25 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CU254_RS16950 dfbc5f577f0bcd89b7126d73c4b08e58 129 SUPERFAMILY SSF55298 6 127 5.18E-29 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CU254_RS16950 dfbc5f577f0bcd89b7126d73c4b08e58 129 Pfam PF01042 Endoribonuclease L-PSP 15 125 2.7E-21 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family CU254_RS12435 8601adeef0cc848e969a9d98d74474c5 287 Pfam PF00753 Metallo-beta-lactamase superfamily 54 265 3.7E-25 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS12435 8601adeef0cc848e969a9d98d74474c5 287 SUPERFAMILY SSF56281 45 283 1.44E-36 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS12435 8601adeef0cc848e969a9d98d74474c5 287 Gene3D G3DSA:3.60.15.10 1 287 9.7E-45 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS12435 8601adeef0cc848e969a9d98d74474c5 287 SMART SM00849 54 265 1.6E-16 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS06595 471c4945ccfa9a04555b29c0bd98173b 182 ProSitePatterns PS01081 TetR-type HTH domain signature. 8 38 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CU254_RS06595 471c4945ccfa9a04555b29c0bd98173b 182 Pfam PF00440 Bacterial regulatory proteins, tetR family 3 40 7.7E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS06595 471c4945ccfa9a04555b29c0bd98173b 182 Gene3D G3DSA:1.10.357.10 36 174 8.7E-20 T 28-03-2018 CU254_RS06595 471c4945ccfa9a04555b29c0bd98173b 182 Gene3D G3DSA:1.10.10.60 1 35 6.7E-10 T 28-03-2018 CU254_RS06595 471c4945ccfa9a04555b29c0bd98173b 182 SUPERFAMILY SSF46689 3 47 1.8E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS06595 471c4945ccfa9a04555b29c0bd98173b 182 SUPERFAMILY SSF48498 61 176 9.85E-28 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS01915 7e8b90ebf502c1faf75ec3c8ff1ede9b 162 SUPERFAMILY SSF55729 17 152 1.65E-24 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS01915 7e8b90ebf502c1faf75ec3c8ff1ede9b 162 Pfam PF00583 Acetyltransferase (GNAT) family 31 141 5.1E-16 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS01915 7e8b90ebf502c1faf75ec3c8ff1ede9b 162 Gene3D G3DSA:3.40.630.30 10 161 1.4E-26 T 28-03-2018 CU254_RS21845 b1bc661410ffae1edebb414dd4e7b47d 283 Pfam PF00106 short chain dehydrogenase 4 186 1.3E-47 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS21845 b1bc661410ffae1edebb414dd4e7b47d 283 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 3.1E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS21845 b1bc661410ffae1edebb414dd4e7b47d 283 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 3.1E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS21845 b1bc661410ffae1edebb414dd4e7b47d 283 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 128 136 3.1E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS21845 b1bc661410ffae1edebb414dd4e7b47d 283 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 5.8E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS21845 b1bc661410ffae1edebb414dd4e7b47d 283 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 5.8E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS21845 b1bc661410ffae1edebb414dd4e7b47d 283 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 5.8E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS21845 b1bc661410ffae1edebb414dd4e7b47d 283 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 5.8E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS21845 b1bc661410ffae1edebb414dd4e7b47d 283 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 5.8E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS21845 b1bc661410ffae1edebb414dd4e7b47d 283 Gene3D G3DSA:3.40.50.720 2 278 1.4E-63 T 28-03-2018 CU254_RS21845 b1bc661410ffae1edebb414dd4e7b47d 283 SUPERFAMILY SSF51735 3 246 8.2E-61 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS12215 6e6cf531ba802a159f4dda646979ed00 263 Pfam PF01958 Domain of unknown function DUF108 167 248 1.1E-20 T 28-03-2018 IPR002811 Aspartate dehydrogenase GO:0006742|GO:0016491|GO:0019363|GO:0055114 KEGG: 00760+1.4.1.21 CU254_RS12215 6e6cf531ba802a159f4dda646979ed00 263 SUPERFAMILY SSF51735 6 120 1.47E-16 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS12215 6e6cf531ba802a159f4dda646979ed00 263 PIRSF PIRSF005227 3 261 3.7E-60 T 28-03-2018 IPR011182 L-aspartate dehydrogenase GO:0009435|GO:0033735|GO:0055114 KEGG: 00760+1.4.1.21 CU254_RS12215 6e6cf531ba802a159f4dda646979ed00 263 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 11 104 6.0E-13 T 28-03-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 CU254_RS12215 6e6cf531ba802a159f4dda646979ed00 263 Gene3D G3DSA:3.40.50.720 3 129 1.6E-13 T 28-03-2018 CU254_RS12215 6e6cf531ba802a159f4dda646979ed00 263 Gene3D G3DSA:3.30.360.10 130 231 3.0E-31 T 28-03-2018 CU254_RS12215 6e6cf531ba802a159f4dda646979ed00 263 SUPERFAMILY SSF55347 115 231 1.9E-17 T 28-03-2018 CU254_RS24125 9e558f632e28b49bfd0146ec1f92c9da 456 Pfam PF00355 Rieske [2Fe-2S] domain 49 132 7.4E-21 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CU254_RS24125 9e558f632e28b49bfd0146ec1f92c9da 456 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 199 387 3.6E-15 T 28-03-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 CU254_RS24125 9e558f632e28b49bfd0146ec1f92c9da 456 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 152 178 6.0E-43 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CU254_RS24125 9e558f632e28b49bfd0146ec1f92c9da 456 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 85 105 6.0E-43 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CU254_RS24125 9e558f632e28b49bfd0146ec1f92c9da 456 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 106 126 6.0E-43 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CU254_RS24125 9e558f632e28b49bfd0146ec1f92c9da 456 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 64 79 6.0E-43 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CU254_RS24125 9e558f632e28b49bfd0146ec1f92c9da 456 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 193 215 6.0E-43 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CU254_RS24125 9e558f632e28b49bfd0146ec1f92c9da 456 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 34 59 6.0E-43 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CU254_RS24125 9e558f632e28b49bfd0146ec1f92c9da 456 Gene3D G3DSA:2.102.10.10 40 149 1.4E-21 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CU254_RS24125 9e558f632e28b49bfd0146ec1f92c9da 456 TIGRFAM TIGR03229 benzo_1_2_benA: benzoate 1,2-dioxygenase, large subunit 14 444 8.3E-243 T 28-03-2018 IPR017639 Benzoate 1,2-dioxygenase, large subunit CU254_RS24125 9e558f632e28b49bfd0146ec1f92c9da 456 SUPERFAMILY SSF50022 14 168 7.2E-48 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CU254_RS24125 9e558f632e28b49bfd0146ec1f92c9da 456 Gene3D G3DSA:3.90.380.10 150 447 4.4E-69 T 28-03-2018 CU254_RS24125 9e558f632e28b49bfd0146ec1f92c9da 456 SUPERFAMILY SSF55961 168 450 1.18E-67 T 28-03-2018 CU254_RS06380 18d81c1a58b2430b5967f21fb260ea5c 246 Gene3D G3DSA:3.20.20.60 1 244 5.9E-54 T 28-03-2018 CU254_RS06380 18d81c1a58b2430b5967f21fb260ea5c 246 SUPERFAMILY SSF51621 3 242 1.26E-54 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CU254_RS06380 18d81c1a58b2430b5967f21fb260ea5c 246 Pfam PF13714 Phosphoenolpyruvate phosphomutase 6 235 6.0E-69 T 28-03-2018 CU254_RS36495 18c63d02c6955e0be6f94c1076ed7f44 195 Gene3D G3DSA:1.10.287.1060 74 163 0.0037 T 28-03-2018 CU254_RS12910 df05062f46f6ac26b2fd79ebfaa50b36 322 Pfam PF00561 alpha/beta hydrolase fold 28 145 1.3E-14 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS12910 df05062f46f6ac26b2fd79ebfaa50b36 322 Gene3D G3DSA:3.40.50.1820 4 277 4.6E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS12910 df05062f46f6ac26b2fd79ebfaa50b36 322 SUPERFAMILY SSF53474 4 275 5.36E-31 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS17355 2f21b0b919dfa032530392ce97eaf3ba 568 SUPERFAMILY SSF53850 10 564 3.62E-73 T 28-03-2018 CU254_RS17355 2f21b0b919dfa032530392ce97eaf3ba 568 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 58 463 4.1E-48 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CU254_RS17355 2f21b0b919dfa032530392ce97eaf3ba 568 Gene3D G3DSA:3.10.105.10 303 532 3.2E-40 T 28-03-2018 CU254_RS17355 2f21b0b919dfa032530392ce97eaf3ba 568 Gene3D G3DSA:3.90.76.10 45 253 1.6E-24 T 28-03-2018 CU254_RS17355 2f21b0b919dfa032530392ce97eaf3ba 568 PIRSF PIRSF002741 2 563 5.6E-44 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CU254_RS06685 536cb772e5e6d451b42145cd3027ceb6 604 Gene3D G3DSA:3.20.20.80 297 573 3.4E-38 T 28-03-2018 CU254_RS06685 536cb772e5e6d451b42145cd3027ceb6 604 Gene3D G3DSA:2.60.120.260 2 192 4.0E-44 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS06685 536cb772e5e6d451b42145cd3027ceb6 604 Gene3D G3DSA:2.60.40.10 193 290 6.2E-14 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS06685 536cb772e5e6d451b42145cd3027ceb6 604 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 331 452 4.6E-8 T 28-03-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 CU254_RS06685 536cb772e5e6d451b42145cd3027ceb6 604 Pfam PF00703 Glycosyl hydrolases family 2 245 289 6.6E-8 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 CU254_RS06685 536cb772e5e6d451b42145cd3027ceb6 604 SUPERFAMILY SSF49785 28 196 2.69E-47 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS06685 536cb772e5e6d451b42145cd3027ceb6 604 SUPERFAMILY SSF51445 287 570 1.11E-62 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS06685 536cb772e5e6d451b42145cd3027ceb6 604 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 88 156 1.2E-12 T 28-03-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CU254_RS06685 536cb772e5e6d451b42145cd3027ceb6 604 SUPERFAMILY SSF49303 191 289 1.06E-12 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 CU254_RS15215 ddb801264d2df2956087f71ecc15d9ba 396 Gene3D G3DSA:1.20.140.10 223 396 4.7E-10 T 28-03-2018 CU254_RS15215 ddb801264d2df2956087f71ecc15d9ba 396 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 253 379 8.5E-14 T 28-03-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain CU254_RS15215 ddb801264d2df2956087f71ecc15d9ba 396 Gene3D G3DSA:2.40.110.10 130 222 7.1E-9 T 28-03-2018 CU254_RS15215 ddb801264d2df2956087f71ecc15d9ba 396 PIRSF PIRSF016578 9 396 5.4E-60 T 28-03-2018 CU254_RS15215 ddb801264d2df2956087f71ecc15d9ba 396 SUPERFAMILY SSF47203 252 393 9.52E-10 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS15215 ddb801264d2df2956087f71ecc15d9ba 396 SUPERFAMILY SSF56645 35 229 3.8E-21 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS15215 ddb801264d2df2956087f71ecc15d9ba 396 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 39 101 1.2E-5 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS15215 ddb801264d2df2956087f71ecc15d9ba 396 Gene3D G3DSA:1.10.540.10 22 120 5.3E-11 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS05930 51f88bc7b143ec4a1c31618f1ac767f0 550 SMART SM00448 4 126 3.0E-10 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS05930 51f88bc7b143ec4a1c31618f1ac767f0 550 SUPERFAMILY SSF51905 225 547 5.86E-38 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS05930 51f88bc7b143ec4a1c31618f1ac767f0 550 SUPERFAMILY SSF52172 7 135 4.41E-21 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS05930 51f88bc7b143ec4a1c31618f1ac767f0 550 Gene3D G3DSA:3.50.50.60 226 374 6.4E-24 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS05930 51f88bc7b143ec4a1c31618f1ac767f0 550 Gene3D G3DSA:3.50.50.60 375 547 4.4E-22 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS05930 51f88bc7b143ec4a1c31618f1ac767f0 550 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 371 389 3.3E-21 T 28-03-2018 CU254_RS05930 51f88bc7b143ec4a1c31618f1ac767f0 550 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 455 471 3.3E-21 T 28-03-2018 CU254_RS05930 51f88bc7b143ec4a1c31618f1ac767f0 550 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 229 248 3.3E-21 T 28-03-2018 CU254_RS05930 51f88bc7b143ec4a1c31618f1ac767f0 550 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 328 346 3.3E-21 T 28-03-2018 CU254_RS05930 51f88bc7b143ec4a1c31618f1ac767f0 550 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 500 522 3.3E-21 T 28-03-2018 CU254_RS05930 51f88bc7b143ec4a1c31618f1ac767f0 550 Pfam PF00072 Response regulator receiver domain 7 119 2.1E-12 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS05930 51f88bc7b143ec4a1c31618f1ac767f0 550 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 227 536 1.9E-28 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS05930 51f88bc7b143ec4a1c31618f1ac767f0 550 Gene3D G3DSA:3.40.50.2300 2 166 7.1E-21 T 28-03-2018 CU254_RS05930 51f88bc7b143ec4a1c31618f1ac767f0 550 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 367 391 5.6E-31 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CU254_RS05930 51f88bc7b143ec4a1c31618f1ac767f0 550 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 228 250 5.6E-31 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CU254_RS05930 51f88bc7b143ec4a1c31618f1ac767f0 550 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 261 276 5.6E-31 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CU254_RS05930 51f88bc7b143ec4a1c31618f1ac767f0 550 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 282 292 5.6E-31 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CU254_RS05930 51f88bc7b143ec4a1c31618f1ac767f0 550 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 528 547 5.6E-31 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CU254_RS05930 51f88bc7b143ec4a1c31618f1ac767f0 550 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 421 437 5.6E-31 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CU254_RS05930 51f88bc7b143ec4a1c31618f1ac767f0 550 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 329 337 5.6E-31 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CU254_RS33095 0c5a47142be7636794b92ca2ed42aaab 1200 SMART SM01043 100 244 1.5E-50 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CU254_RS33095 0c5a47142be7636794b92ca2ed42aaab 1200 SUPERFAMILY SSF52540 258 542 4.03E-17 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS33095 0c5a47142be7636794b92ca2ed42aaab 1200 Gene3D G3DSA:3.40.50.300 264 436 2.6E-12 T 28-03-2018 CU254_RS33095 0c5a47142be7636794b92ca2ed42aaab 1200 SMART SM00862 13 93 9.6E-8 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS33095 0c5a47142be7636794b92ca2ed42aaab 1200 Gene3D G3DSA:1.25.40.10 102 263 3.0E-24 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS33095 0c5a47142be7636794b92ca2ed42aaab 1200 SUPERFAMILY SSF46894 1131 1197 3.4E-13 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS33095 0c5a47142be7636794b92ca2ed42aaab 1200 Pfam PF03704 Bacterial transcriptional activator domain 100 244 5.5E-43 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CU254_RS33095 0c5a47142be7636794b92ca2ed42aaab 1200 ProSitePatterns PS00622 LuxR-type HTH domain signature. 1155 1182 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS33095 0c5a47142be7636794b92ca2ed42aaab 1200 SUPERFAMILY SSF48452 881 984 7.12E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS33095 0c5a47142be7636794b92ca2ed42aaab 1200 SUPERFAMILY SSF48452 1063 1109 7.12E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS33095 0c5a47142be7636794b92ca2ed42aaab 1200 Gene3D G3DSA:1.10.10.10 3 101 1.1E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS33095 0c5a47142be7636794b92ca2ed42aaab 1200 SMART SM00421 1138 1195 8.1E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS33095 0c5a47142be7636794b92ca2ed42aaab 1200 Pfam PF00486 Transcriptional regulatory protein, C terminal 21 83 5.7E-8 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS33095 0c5a47142be7636794b92ca2ed42aaab 1200 Gene3D G3DSA:1.25.40.10 664 908 7.1E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS33095 0c5a47142be7636794b92ca2ed42aaab 1200 Gene3D G3DSA:1.25.40.10 978 1149 1.4E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS33095 0c5a47142be7636794b92ca2ed42aaab 1200 Pfam PF00196 Bacterial regulatory proteins, luxR family 1140 1193 7.4E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS33095 0c5a47142be7636794b92ca2ed42aaab 1200 Pfam PF13191 AAA ATPase domain 268 423 8.7E-19 T 28-03-2018 CU254_RS33095 0c5a47142be7636794b92ca2ed42aaab 1200 SUPERFAMILY SSF48452 97 264 1.09E-33 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS33095 0c5a47142be7636794b92ca2ed42aaab 1200 Gene3D G3DSA:1.25.40.10 915 977 0.14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS33095 0c5a47142be7636794b92ca2ed42aaab 1200 Gene3D G3DSA:1.10.10.10 1150 1200 5.5E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS33095 0c5a47142be7636794b92ca2ed42aaab 1200 SUPERFAMILY SSF46894 3 86 1.67E-11 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS33095 0c5a47142be7636794b92ca2ed42aaab 1200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 1171 1183 1.8E-6 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS33095 0c5a47142be7636794b92ca2ed42aaab 1200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 1141 1155 1.8E-6 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS33095 0c5a47142be7636794b92ca2ed42aaab 1200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 1155 1171 1.8E-6 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS13695 df32620ad598cf45ecd3975093924eda 210 Gene3D G3DSA:3.40.50.150 5 196 7.4E-32 T 28-03-2018 CU254_RS13695 df32620ad598cf45ecd3975093924eda 210 Pfam PF13649 Methyltransferase domain 46 137 1.0E-17 T 28-03-2018 CU254_RS13695 df32620ad598cf45ecd3975093924eda 210 SUPERFAMILY SSF53335 9 209 4.82E-33 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS12835 f6819e81d5ef57b9fd089969f8c4a5b1 798 Gene3D G3DSA:3.40.50.970 213 386 6.5E-6 T 28-03-2018 CU254_RS12835 f6819e81d5ef57b9fd089969f8c4a5b1 798 Gene3D G3DSA:3.40.50.970 590 758 0.0032 T 28-03-2018 CU254_RS12835 f6819e81d5ef57b9fd089969f8c4a5b1 798 Gene3D G3DSA:3.40.50.1220 395 564 6.7E-7 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CU254_RS27360 a1fd68bf7fe75546b96672c63eb5bf19 292 Gene3D G3DSA:3.40.190.10 88 175 1.7E-25 T 28-03-2018 CU254_RS27360 a1fd68bf7fe75546b96672c63eb5bf19 292 SUPERFAMILY SSF46785 2 84 4.92E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS27360 a1fd68bf7fe75546b96672c63eb5bf19 292 Pfam PF03466 LysR substrate binding domain 88 291 2.0E-43 T 28-03-2018 IPR005119 LysR, substrate-binding CU254_RS27360 a1fd68bf7fe75546b96672c63eb5bf19 292 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 3.8E-24 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS27360 a1fd68bf7fe75546b96672c63eb5bf19 292 SUPERFAMILY SSF53850 91 291 3.48E-41 T 28-03-2018 CU254_RS27360 a1fd68bf7fe75546b96672c63eb5bf19 292 Gene3D G3DSA:3.40.190.10 176 267 1.2E-25 T 28-03-2018 CU254_RS27360 a1fd68bf7fe75546b96672c63eb5bf19 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.1E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS27360 a1fd68bf7fe75546b96672c63eb5bf19 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.1E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS27360 a1fd68bf7fe75546b96672c63eb5bf19 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.1E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS27360 a1fd68bf7fe75546b96672c63eb5bf19 292 Gene3D G3DSA:1.10.10.10 1 83 3.0E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS26805 ee71d85fb92acfa89057e79a87c5fbdb 541 ProSitePatterns PS00455 Putative AMP-binding domain signature. 187 198 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS26805 ee71d85fb92acfa89057e79a87c5fbdb 541 SUPERFAMILY SSF56801 22 529 1.44E-139 T 28-03-2018 CU254_RS26805 ee71d85fb92acfa89057e79a87c5fbdb 541 Pfam PF13193 AMP-binding enzyme C-terminal domain 444 519 3.6E-12 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS26805 ee71d85fb92acfa89057e79a87c5fbdb 541 Gene3D G3DSA:3.40.50.980 23 191 2.6E-42 T 28-03-2018 CU254_RS26805 ee71d85fb92acfa89057e79a87c5fbdb 541 Gene3D G3DSA:2.30.38.10 355 427 1.4E-21 T 28-03-2018 CU254_RS26805 ee71d85fb92acfa89057e79a87c5fbdb 541 Gene3D G3DSA:3.30.300.30 429 536 2.9E-23 T 28-03-2018 CU254_RS26805 ee71d85fb92acfa89057e79a87c5fbdb 541 Pfam PF00501 AMP-binding enzyme 31 434 1.3E-92 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS26805 ee71d85fb92acfa89057e79a87c5fbdb 541 Gene3D G3DSA:3.40.50.980 192 352 4.5E-38 T 28-03-2018 CU254_RS36170 99f2fbd4a74688b9c6341e6f779a9ba9 510 SUPERFAMILY SSF55729 376 507 1.53E-26 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS36170 99f2fbd4a74688b9c6341e6f779a9ba9 510 Pfam PF13673 Acetyltransferase (GNAT) domain 415 499 1.8E-15 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS36170 99f2fbd4a74688b9c6341e6f779a9ba9 510 Gene3D G3DSA:3.40.630.30 367 510 5.6E-25 T 28-03-2018 CU254_RS35245 780d59e0704945cc789b06fa9ac55b4b 156 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 4 149 1.1E-54 T 28-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 CU254_RS35245 780d59e0704945cc789b06fa9ac55b4b 156 Pfam PF01967 MoaC family 15 148 1.4E-46 T 28-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CU254_RS35245 780d59e0704945cc789b06fa9ac55b4b 156 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase accessory protein [moaC]. 2 156 32.689 T 28-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 CU254_RS35245 780d59e0704945cc789b06fa9ac55b4b 156 SUPERFAMILY SSF55040 11 153 6.28E-51 T 28-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CU254_RS35245 780d59e0704945cc789b06fa9ac55b4b 156 Gene3D G3DSA:3.30.70.640 2 156 1.4E-58 T 28-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CU254_RS38365 b1b7df6199983e2821b5f30552d4bbba 164 Pfam PF00188 Cysteine-rich secretory protein family 50 162 1.3E-20 T 28-03-2018 IPR014044 CAP domain CU254_RS38365 b1b7df6199983e2821b5f30552d4bbba 164 Gene3D G3DSA:3.40.33.10 38 161 3.7E-17 T 28-03-2018 IPR014044 CAP domain CU254_RS38365 b1b7df6199983e2821b5f30552d4bbba 164 SUPERFAMILY SSF55797 45 163 5.49E-21 T 28-03-2018 IPR014044 CAP domain CU254_RS11605 9aa494b7e3d00fa198ae2f152f4180b1 168 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 19 155 9.1E-51 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CU254_RS11605 9aa494b7e3d00fa198ae2f152f4180b1 168 Gene3D G3DSA:3.40.50.960 7 160 1.1E-54 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CU254_RS11605 9aa494b7e3d00fa198ae2f152f4180b1 168 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 14 158 27.037 T 28-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CU254_RS11605 9aa494b7e3d00fa198ae2f152f4180b1 168 SUPERFAMILY SSF52121 13 158 2.88E-52 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CU254_RS11605 9aa494b7e3d00fa198ae2f152f4180b1 168 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 19 154 6.5E-43 T 28-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CU254_RS34430 f25c2c92031604983d860b6563871e0c 292 SUPERFAMILY SSF63829 5 229 2.29E-14 T 28-03-2018 CU254_RS34430 f25c2c92031604983d860b6563871e0c 292 Gene3D G3DSA:2.120.10.30 166 291 3.8E-5 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CU254_RS34430 f25c2c92031604983d860b6563871e0c 292 Gene3D G3DSA:2.120.10.30 2 165 9.0E-13 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CU254_RS16800 355f146800ff3db2f1e599d939f1e0d1 166 Pfam PF12802 MarR family 37 95 8.7E-10 T 28-03-2018 CU254_RS16800 355f146800ff3db2f1e599d939f1e0d1 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 55 71 5.1E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS16800 355f146800ff3db2f1e599d939f1e0d1 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 72 87 5.1E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS16800 355f146800ff3db2f1e599d939f1e0d1 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 122 142 5.1E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS16800 355f146800ff3db2f1e599d939f1e0d1 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 91 107 5.1E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS16800 355f146800ff3db2f1e599d939f1e0d1 166 Gene3D G3DSA:1.10.10.10 10 149 8.7E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS16800 355f146800ff3db2f1e599d939f1e0d1 166 SUPERFAMILY SSF46785 11 146 1.02E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS16800 355f146800ff3db2f1e599d939f1e0d1 166 SMART SM00347 30 132 1.6E-14 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS01800 bcee2fd944bf4a979e6736d2de0d07b6 420 Pfam PF02470 MlaD protein 39 114 1.1E-14 T 28-03-2018 IPR003399 Mce/MlaD CU254_RS01800 bcee2fd944bf4a979e6736d2de0d07b6 420 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 9 297 1.4E-58 T 28-03-2018 IPR005693 Virulence factor Mce protein CU254_RS34175 7d85b22ba6b167b60db1789f276a0e53 353 SUPERFAMILY SSF51735 162 344 2.47E-79 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS34175 7d85b22ba6b167b60db1789f276a0e53 353 SUPERFAMILY SSF51735 2 125 2.47E-79 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS34175 7d85b22ba6b167b60db1789f276a0e53 353 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 266 1.2E-44 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CU254_RS34175 7d85b22ba6b167b60db1789f276a0e53 353 Gene3D G3DSA:3.90.25.10 211 349 5.3E-34 T 28-03-2018 CU254_RS34175 7d85b22ba6b167b60db1789f276a0e53 353 Gene3D G3DSA:3.40.50.720 2 210 7.0E-33 T 28-03-2018 CU254_RS05875 2608a747b31f23e781e5b830fbe73842 572 Pfam PF13454 FAD-NAD(P)-binding 7 163 5.8E-16 T 28-03-2018 CU254_RS05875 2608a747b31f23e781e5b830fbe73842 572 Gene3D G3DSA:3.50.50.60 172 511 0.12 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS05875 2608a747b31f23e781e5b830fbe73842 572 Gene3D G3DSA:3.50.50.60 5 171 0.012 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS40820 ed3fcba73cb78fa12482a67932b5ed8b 193 SUPERFAMILY SSF51182 89 178 1.87E-19 T 28-03-2018 IPR011051 RmlC-like cupin domain CU254_RS40820 ed3fcba73cb78fa12482a67932b5ed8b 193 SMART SM00530 17 72 3.0E-16 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS40820 ed3fcba73cb78fa12482a67932b5ed8b 193 Pfam PF01381 Helix-turn-helix 18 72 1.3E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS40820 ed3fcba73cb78fa12482a67932b5ed8b 193 Gene3D G3DSA:2.60.120.10 70 191 1.4E-20 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS40820 ed3fcba73cb78fa12482a67932b5ed8b 193 SUPERFAMILY SSF47413 11 74 4.22E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS40820 ed3fcba73cb78fa12482a67932b5ed8b 193 Pfam PF07883 Cupin domain 110 177 1.4E-14 T 28-03-2018 IPR013096 Cupin 2, conserved barrel CU254_RS40820 ed3fcba73cb78fa12482a67932b5ed8b 193 Gene3D G3DSA:1.10.260.40 7 69 2.6E-18 T 28-03-2018 CU254_RS40750 077a44f823d90cbe1b4350eb6a3196fa 217 Pfam PF12697 Alpha/beta hydrolase family 6 206 1.9E-15 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS40750 077a44f823d90cbe1b4350eb6a3196fa 217 SUPERFAMILY SSF53474 5 210 2.08E-24 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS40750 077a44f823d90cbe1b4350eb6a3196fa 217 Gene3D G3DSA:3.40.50.1820 3 217 9.1E-22 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS13460 fabe86a2548b77cfb5674d8b45c24f89 653 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 275 2.9E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS13460 fabe86a2548b77cfb5674d8b45c24f89 653 SUPERFAMILY SSF52540 333 580 1.01E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS13460 fabe86a2548b77cfb5674d8b45c24f89 653 SMART SM00382 364 554 1.5E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS13460 fabe86a2548b77cfb5674d8b45c24f89 653 Pfam PF00005 ABC transporter 356 504 2.3E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS13460 fabe86a2548b77cfb5674d8b45c24f89 653 SUPERFAMILY SSF161098 80 272 1.31E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS13460 fabe86a2548b77cfb5674d8b45c24f89 653 Gene3D G3DSA:3.40.50.300 332 648 2.4E-69 T 28-03-2018 CU254_RS13460 fabe86a2548b77cfb5674d8b45c24f89 653 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 557 620 9.9E-15 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CU254_RS13460 fabe86a2548b77cfb5674d8b45c24f89 653 Gene3D G3DSA:1.10.3720.10 14 276 2.3E-37 T 28-03-2018 CU254_RS13460 fabe86a2548b77cfb5674d8b45c24f89 653 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 554 638 3.3E-19 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CU254_RS13460 fabe86a2548b77cfb5674d8b45c24f89 653 ProSitePatterns PS00211 ABC transporters family signature. 477 491 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS30500 55ef8fc46de916b4dbc566aae2a388bf 250 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 38 53 9.4E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS30500 55ef8fc46de916b4dbc566aae2a388bf 250 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 53 68 9.4E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS30500 55ef8fc46de916b4dbc566aae2a388bf 250 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 5 20 9.4E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS30500 55ef8fc46de916b4dbc566aae2a388bf 250 SUPERFAMILY SSF55961 105 243 1.85E-36 T 28-03-2018 CU254_RS30500 55ef8fc46de916b4dbc566aae2a388bf 250 SUPERFAMILY SSF46785 1 101 2.05E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS30500 55ef8fc46de916b4dbc566aae2a388bf 250 Gene3D G3DSA:1.10.10.10 1 102 2.2E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS30500 55ef8fc46de916b4dbc566aae2a388bf 250 Gene3D G3DSA:3.30.530.20 103 242 1.7E-30 T 28-03-2018 IPR023393 START-like domain CU254_RS30500 55ef8fc46de916b4dbc566aae2a388bf 250 Pfam PF12840 Helix-turn-helix domain 2 62 3.6E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS30500 55ef8fc46de916b4dbc566aae2a388bf 250 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 116 237 3.1E-24 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CU254_RS30500 55ef8fc46de916b4dbc566aae2a388bf 250 SMART SM00418 3 82 4.4E-18 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS42335 126bea6e4998498ae6cd4955c862c0d5 284 Gene3D G3DSA:1.10.260.40 14 101 3.0E-13 T 28-03-2018 CU254_RS42335 126bea6e4998498ae6cd4955c862c0d5 284 SMART SM00530 21 90 3.7E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS42335 126bea6e4998498ae6cd4955c862c0d5 284 Pfam PF13560 Helix-turn-helix domain 18 93 9.4E-12 T 28-03-2018 CU254_RS42335 126bea6e4998498ae6cd4955c862c0d5 284 SUPERFAMILY SSF47413 40 89 2.11E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS16405 8c405668ef96e5ad6316e512274ac891 374 Gene3D G3DSA:3.20.20.140 46 333 5.0E-39 T 28-03-2018 CU254_RS16405 8c405668ef96e5ad6316e512274ac891 374 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 37 45 - T 28-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 CU254_RS16405 8c405668ef96e5ad6316e512274ac891 374 SUPERFAMILY SSF51556 36 342 5.05E-73 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS16405 8c405668ef96e5ad6316e512274ac891 374 Pfam PF07969 Amidohydrolase family 84 371 5.5E-18 T 28-03-2018 IPR013108 Amidohydrolase 3 CU254_RS16405 8c405668ef96e5ad6316e512274ac891 374 Gene3D G3DSA:2.30.40.10 1 45 3.8E-12 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS16405 8c405668ef96e5ad6316e512274ac891 374 SUPERFAMILY SSF51338 1 50 2.05E-11 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS28705 bf5399cff0eff8475b9e0ac864d88a8d 183 TIGRFAM TIGR04178 exo_archaeo: exosortase/archaeosortase family protein 81 171 1.5E-11 T 28-03-2018 IPR026392 Exosortase/Archaeosortase domain CU254_RS42405 590e430c24e40776ecb762d9879da082 67 Gene3D G3DSA:1.10.1220.10 3 52 2.8E-4 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CU254_RS24870 93c93e0479d95da00ee8dc0d12ad36f6 249 Gene3D G3DSA:3.40.50.720 5 124 7.8E-24 T 28-03-2018 CU254_RS24870 93c93e0479d95da00ee8dc0d12ad36f6 249 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 6 108 5.7E-26 T 28-03-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CU254_RS24870 93c93e0479d95da00ee8dc0d12ad36f6 249 SUPERFAMILY SSF51735 5 135 2.15E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS24870 93c93e0479d95da00ee8dc0d12ad36f6 249 SUPERFAMILY SSF55347 109 219 5.89E-37 T 28-03-2018 CU254_RS24870 93c93e0479d95da00ee8dc0d12ad36f6 249 PIRSF PIRSF000161 4 249 8.9E-67 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CU254_RS24870 93c93e0479d95da00ee8dc0d12ad36f6 249 Gene3D G3DSA:3.30.360.10 125 216 1.3E-34 T 28-03-2018 CU254_RS24870 93c93e0479d95da00ee8dc0d12ad36f6 249 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 111 247 3.7E-31 T 28-03-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CU254_RS24870 93c93e0479d95da00ee8dc0d12ad36f6 249 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 44 248 8.7E-57 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CU254_RS24870 93c93e0479d95da00ee8dc0d12ad36f6 249 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 6 248 29.613 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CU254_RS24870 93c93e0479d95da00ee8dc0d12ad36f6 249 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 130 147 - T 28-03-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CU254_RS05645 f03f0f3be2033cc7648c3b3db36b6b97 281 Pfam PF13349 Putative adhesin 21 255 1.2E-11 T 28-03-2018 IPR025164 Putative adhesin CU254_RS17460 565df1f0edfaafb3b195a1a53f9b429f 230 SUPERFAMILY SSF46785 7 116 6.39E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS17460 565df1f0edfaafb3b195a1a53f9b429f 230 Gene3D G3DSA:1.10.10.10 2 116 3.4E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS17460 565df1f0edfaafb3b195a1a53f9b429f 230 Gene3D G3DSA:3.30.1050.10 117 216 7.1E-15 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CU254_RS17460 565df1f0edfaafb3b195a1a53f9b429f 230 SUPERFAMILY SSF55718 135 214 5.59E-13 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CU254_RS17460 565df1f0edfaafb3b195a1a53f9b429f 230 Pfam PF01638 HxlR-like helix-turn-helix 19 105 1.1E-20 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type CU254_RS17460 565df1f0edfaafb3b195a1a53f9b429f 230 Pfam PF02036 SCP-2 sterol transfer family 129 207 1.3E-8 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CU254_RS16275 af502946c2074ec3ba6f9a1d7d16aa14 315 Gene3D G3DSA:3.40.50.720 2 177 1.4E-11 T 28-03-2018 CU254_RS16275 af502946c2074ec3ba6f9a1d7d16aa14 315 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 103 9.7E-10 T 28-03-2018 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CU254_RS21615 1c6a7c8e1fd03cf8b017cee7b401973e 161 Gene3D G3DSA:1.20.1440.20 18 160 4.0E-33 T 28-03-2018 CU254_RS21615 1c6a7c8e1fd03cf8b017cee7b401973e 161 SUPERFAMILY SSF140478 30 129 5.75E-5 T 28-03-2018 IPR023353 LemA-like domain CU254_RS02410 7a32243f6da2bd6ae873ef712e506854 190 Gene3D G3DSA:1.10.1740.10 8 108 1.0E-21 T 28-03-2018 CU254_RS02410 7a32243f6da2bd6ae873ef712e506854 190 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 22 184 1.1E-27 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS02410 7a32243f6da2bd6ae873ef712e506854 190 SUPERFAMILY SSF88659 113 185 4.49E-16 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS02410 7a32243f6da2bd6ae873ef712e506854 190 SUPERFAMILY SSF88946 9 111 3.92E-19 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS02410 7a32243f6da2bd6ae873ef712e506854 190 Gene3D G3DSA:1.10.10.10 109 190 1.4E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS02410 7a32243f6da2bd6ae873ef712e506854 190 Pfam PF08281 Sigma-70, region 4 129 180 8.2E-12 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS02410 7a32243f6da2bd6ae873ef712e506854 190 Pfam PF04542 Sigma-70 region 2 26 98 1.4E-13 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS27470 e5f371de3d0ae616138462265cc4fb55 291 Pfam PF00296 Luciferase-like monooxygenase 9 231 2.4E-53 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS27470 e5f371de3d0ae616138462265cc4fb55 291 Gene3D G3DSA:3.20.20.30 6 259 6.0E-66 T 28-03-2018 CU254_RS27470 e5f371de3d0ae616138462265cc4fb55 291 SUPERFAMILY SSF51679 1 286 1.12E-59 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS27470 e5f371de3d0ae616138462265cc4fb55 291 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 18 250 1.4E-64 T 28-03-2018 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted CU254_RS18990 86b952a4b66e0d3b41bb45c652e9e587 253 Gene3D G3DSA:3.30.60.20 174 249 7.6E-15 T 28-03-2018 CU254_RS18990 86b952a4b66e0d3b41bb45c652e9e587 253 Gene3D G3DSA:3.40.50.300 31 170 8.8E-37 T 28-03-2018 CU254_RS18990 86b952a4b66e0d3b41bb45c652e9e587 253 Pfam PF00265 Thymidine kinase 32 195 7.9E-22 T 28-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 CU254_RS18990 86b952a4b66e0d3b41bb45c652e9e587 253 SUPERFAMILY SSF52540 32 167 2.5E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS15265 88d10335ef6489a0dc469cd3f951fa43 457 Gene3D G3DSA:3.50.50.60 273 455 1.1E-32 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS15265 88d10335ef6489a0dc469cd3f951fa43 457 SUPERFAMILY SSF51905 287 428 7.59E-13 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS15265 88d10335ef6489a0dc469cd3f951fa43 457 Gene3D G3DSA:3.40.50.720 167 255 2.1E-5 T 28-03-2018 CU254_RS15265 88d10335ef6489a0dc469cd3f951fa43 457 PIRSF PIRSF000332 4 429 2.2E-94 T 28-03-2018 CU254_RS15265 88d10335ef6489a0dc469cd3f951fa43 457 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 56 74 8.3E-44 T 28-03-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 CU254_RS15265 88d10335ef6489a0dc469cd3f951fa43 457 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 302 329 8.3E-44 T 28-03-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 CU254_RS15265 88d10335ef6489a0dc469cd3f951fa43 457 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 165 179 8.3E-44 T 28-03-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 CU254_RS15265 88d10335ef6489a0dc469cd3f951fa43 457 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 134 150 8.3E-44 T 28-03-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 CU254_RS15265 88d10335ef6489a0dc469cd3f951fa43 457 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 349 366 8.3E-44 T 28-03-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 CU254_RS15265 88d10335ef6489a0dc469cd3f951fa43 457 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 6 22 8.3E-44 T 28-03-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 CU254_RS15265 88d10335ef6489a0dc469cd3f951fa43 457 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 105 117 8.3E-44 T 28-03-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 CU254_RS15265 88d10335ef6489a0dc469cd3f951fa43 457 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 80 95 8.3E-44 T 28-03-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 CU254_RS15265 88d10335ef6489a0dc469cd3f951fa43 457 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 192 207 8.3E-44 T 28-03-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 CU254_RS15265 88d10335ef6489a0dc469cd3f951fa43 457 Pfam PF00743 Flavin-binding monooxygenase-like 7 426 8.4E-86 T 28-03-2018 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 CU254_RS15265 88d10335ef6489a0dc469cd3f951fa43 457 PRINTS PR01125 Flavin-containing monooxygenase (FMO) 5 signature 387 406 1.7E-7 T 28-03-2018 IPR002257 Flavin monooxygenase (FMO) 5 GO:0004499|GO:0055114 KEGG: 00982+1.14.13.8 CU254_RS15265 88d10335ef6489a0dc469cd3f951fa43 457 PRINTS PR01125 Flavin-containing monooxygenase (FMO) 5 signature 88 100 1.7E-7 T 28-03-2018 IPR002257 Flavin monooxygenase (FMO) 5 GO:0004499|GO:0055114 KEGG: 00982+1.14.13.8 CU254_RS15265 88d10335ef6489a0dc469cd3f951fa43 457 PRINTS PR01125 Flavin-containing monooxygenase (FMO) 5 signature 262 273 1.7E-7 T 28-03-2018 IPR002257 Flavin monooxygenase (FMO) 5 GO:0004499|GO:0055114 KEGG: 00982+1.14.13.8 CU254_RS15265 88d10335ef6489a0dc469cd3f951fa43 457 PRINTS PR01125 Flavin-containing monooxygenase (FMO) 5 signature 406 417 1.7E-7 T 28-03-2018 IPR002257 Flavin monooxygenase (FMO) 5 GO:0004499|GO:0055114 KEGG: 00982+1.14.13.8 CU254_RS15265 88d10335ef6489a0dc469cd3f951fa43 457 Gene3D G3DSA:3.50.50.60 5 166 2.4E-37 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS15265 88d10335ef6489a0dc469cd3f951fa43 457 SUPERFAMILY SSF51905 4 240 2.53E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS23860 18bfbb4ce8f29502f314905370f6e78a 110 SUPERFAMILY SSF54593 10 108 1.16E-15 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS23860 18bfbb4ce8f29502f314905370f6e78a 110 Gene3D G3DSA:3.10.180.10 7 109 7.1E-15 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS22045 8094897defd38b469996a9d22c636628 223 Pfam PF07729 FCD domain 83 204 1.5E-19 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS22045 8094897defd38b469996a9d22c636628 223 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 73 1.2E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS22045 8094897defd38b469996a9d22c636628 223 SUPERFAMILY SSF48008 79 213 2.88E-17 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS22045 8094897defd38b469996a9d22c636628 223 Gene3D G3DSA:1.20.120.530 76 221 2.7E-22 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS22045 8094897defd38b469996a9d22c636628 223 SUPERFAMILY SSF46785 9 77 3.64E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS22045 8094897defd38b469996a9d22c636628 223 SMART SM00895 83 205 4.2E-11 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS22045 8094897defd38b469996a9d22c636628 223 Gene3D G3DSA:1.10.10.10 1 75 3.8E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS22045 8094897defd38b469996a9d22c636628 223 SMART SM00345 15 73 4.7E-12 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS24965 b63d5661b7d28b6f7dc99d145bd82c38 352 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 1 339 27.029 T 28-03-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 CU254_RS24965 b63d5661b7d28b6f7dc99d145bd82c38 352 Gene3D G3DSA:3.30.300.20 258 329 1.8E-17 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CU254_RS24965 b63d5661b7d28b6f7dc99d145bd82c38 352 Gene3D G3DSA:3.30.1480.10 1 99 3.8E-29 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CU254_RS24965 b63d5661b7d28b6f7dc99d145bd82c38 352 SUPERFAMILY SSF69705 4 99 7.32E-29 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CU254_RS24965 b63d5661b7d28b6f7dc99d145bd82c38 352 Gene3D G3DSA:3.30.300.20 179 256 1.4E-32 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CU254_RS24965 b63d5661b7d28b6f7dc99d145bd82c38 352 SUPERFAMILY SSF54814 180 258 5.75E-28 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CU254_RS24965 b63d5661b7d28b6f7dc99d145bd82c38 352 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 75 322 5.7E-101 T 28-03-2018 IPR010213 Transcription termination factor NusA GO:0003723 CU254_RS24965 b63d5661b7d28b6f7dc99d145bd82c38 352 Pfam PF13184 NusA-like KH domain 210 277 1.7E-26 T 28-03-2018 IPR025249 KH domain, NusA-like GO:0003723 CU254_RS24965 b63d5661b7d28b6f7dc99d145bd82c38 352 SUPERFAMILY SSF54814 259 322 4.77E-17 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CU254_RS24965 b63d5661b7d28b6f7dc99d145bd82c38 352 Pfam PF08529 NusA N-terminal domain 67 100 1.1E-6 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CU254_RS24965 b63d5661b7d28b6f7dc99d145bd82c38 352 Pfam PF08529 NusA N-terminal domain 6 61 6.2E-10 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CU254_RS24965 b63d5661b7d28b6f7dc99d145bd82c38 352 Gene3D G3DSA:2.40.50.140 105 178 1.6E-11 T 28-03-2018 CU254_RS24965 b63d5661b7d28b6f7dc99d145bd82c38 352 SUPERFAMILY SSF50249 110 179 3.9E-16 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CU254_RS20195 197501c80f6f9b2d9e6f1091bce1e584 190 Pfam PF16859 Bacterial transcriptional repressor C-terminal 78 180 1.3E-11 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS20195 197501c80f6f9b2d9e6f1091bce1e584 190 Gene3D G3DSA:1.10.10.60 10 65 1.9E-18 T 28-03-2018 CU254_RS20195 197501c80f6f9b2d9e6f1091bce1e584 190 SUPERFAMILY SSF46689 8 69 2.54E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS20195 197501c80f6f9b2d9e6f1091bce1e584 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 4.0E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS20195 197501c80f6f9b2d9e6f1091bce1e584 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 4.0E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS20195 197501c80f6f9b2d9e6f1091bce1e584 190 SUPERFAMILY SSF48498 79 186 3.38E-10 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS20195 197501c80f6f9b2d9e6f1091bce1e584 190 Gene3D G3DSA:1.10.357.10 66 190 1.3E-11 T 28-03-2018 CU254_RS20195 197501c80f6f9b2d9e6f1091bce1e584 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 64 1.0E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS42085 ad5a073de08adbe7f74c20a91bcba33e 306 PIRSF PIRSF015582 3 286 1.4E-74 T 28-03-2018 IPR011206 Citrate lyase beta subunit-like CU254_RS42085 ad5a073de08adbe7f74c20a91bcba33e 306 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 20 222 9.4E-42 T 28-03-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 CU254_RS42085 ad5a073de08adbe7f74c20a91bcba33e 306 SUPERFAMILY SSF51621 16 234 3.84E-60 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CU254_RS42085 ad5a073de08adbe7f74c20a91bcba33e 306 Gene3D G3DSA:3.20.20.360 4 260 3.1E-52 T 28-03-2018 CU254_RS11885 dbb09b20e15575ae31cf04b8e2fbebd4 161 Pfam PF00583 Acetyltransferase (GNAT) family 19 134 1.2E-18 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS11885 dbb09b20e15575ae31cf04b8e2fbebd4 161 SUPERFAMILY SSF55729 1 146 1.89E-29 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS11885 dbb09b20e15575ae31cf04b8e2fbebd4 161 Gene3D G3DSA:3.40.630.30 83 151 5.5E-15 T 28-03-2018 CU254_RS11885 dbb09b20e15575ae31cf04b8e2fbebd4 161 Gene3D G3DSA:3.40.630.30 1 82 6.5E-14 T 28-03-2018 CU254_RS18245 3d2ae260f84ce0683a044113fe385d44 411 SUPERFAMILY SSF88659 106 166 2.06E-8 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS18245 3d2ae260f84ce0683a044113fe385d44 411 Pfam PF08281 Sigma-70, region 4 116 163 4.1E-6 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS18245 3d2ae260f84ce0683a044113fe385d44 411 Pfam PF09976 Tetratricopeptide repeat-like domain 335 411 3.2E-6 T 28-03-2018 IPR018704 Tetratricopeptide repeat-like domain Reactome: R-HSA-192823|Reactome: R-HSA-381038|Reactome: R-HSA-381426|Reactome: R-HSA-6798695|Reactome: R-HSA-8957275 CU254_RS18245 3d2ae260f84ce0683a044113fe385d44 411 Pfam PF04542 Sigma-70 region 2 13 77 1.5E-7 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS18245 3d2ae260f84ce0683a044113fe385d44 411 Gene3D G3DSA:1.25.40.10 305 411 2.4E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS18245 3d2ae260f84ce0683a044113fe385d44 411 Gene3D G3DSA:1.10.10.10 71 174 2.5E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS18245 3d2ae260f84ce0683a044113fe385d44 411 Gene3D G3DSA:1.10.1740.10 3 70 1.5E-12 T 28-03-2018 CU254_RS18245 3d2ae260f84ce0683a044113fe385d44 411 SUPERFAMILY SSF88946 5 74 7.85E-10 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS03250 6ba7b2666b897e68496bdf112d08ca09 261 Pfam PF01609 Transposase DDE domain 96 248 4.0E-24 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CU254_RS03250 6ba7b2666b897e68496bdf112d08ca09 261 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 1 78 2.9E-28 T 28-03-2018 IPR025161 Putative transposase IS4/IS5 family CU254_RS24055 b7d6830a0455b912ab226a5aed9dc6ee 326 Gene3D G3DSA:1.10.3720.10 34 322 9.0E-33 T 28-03-2018 CU254_RS24055 b7d6830a0455b912ab226a5aed9dc6ee 326 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 27 317 4.6E-76 T 28-03-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 CU254_RS24055 b7d6830a0455b912ab226a5aed9dc6ee 326 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 100 314 2.3E-12 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS24055 b7d6830a0455b912ab226a5aed9dc6ee 326 SUPERFAMILY SSF161098 47 309 2.09E-32 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS33495 51b10a101c3946162618c5966f9512dd 294 SMART SM00382 31 208 3.9E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS33495 51b10a101c3946162618c5966f9512dd 294 SUPERFAMILY SSF52540 5 220 1.05E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS33495 51b10a101c3946162618c5966f9512dd 294 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS33495 51b10a101c3946162618c5966f9512dd 294 Pfam PF00005 ABC transporter 23 159 4.9E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS33495 51b10a101c3946162618c5966f9512dd 294 Gene3D G3DSA:3.40.50.300 3 262 6.0E-61 T 28-03-2018 CU254_RS17845 b1a3f7a1738226d9e2eb14c0ddb4c5c3 925 Gene3D G3DSA:3.50.50.60 73 223 3.5E-16 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS17845 b1a3f7a1738226d9e2eb14c0ddb4c5c3 925 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 224 232 9.2E-8 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CU254_RS17845 b1a3f7a1738226d9e2eb14c0ddb4c5c3 925 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 120 142 9.2E-8 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CU254_RS17845 b1a3f7a1738226d9e2eb14c0ddb4c5c3 925 Gene3D G3DSA:3.30.1360.120 674 782 1.5E-14 T 28-03-2018 CU254_RS17845 b1a3f7a1738226d9e2eb14c0ddb4c5c3 925 SUPERFAMILY SSF101790 827 922 2.45E-15 T 28-03-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain CU254_RS17845 b1a3f7a1738226d9e2eb14c0ddb4c5c3 925 SUPERFAMILY SSF103025 538 823 3.77E-90 T 28-03-2018 CU254_RS17845 b1a3f7a1738226d9e2eb14c0ddb4c5c3 925 Gene3D G3DSA:4.10.1250.10 784 823 1.4E-9 T 28-03-2018 CU254_RS17845 b1a3f7a1738226d9e2eb14c0ddb4c5c3 925 SUPERFAMILY SSF51905 109 412 1.94E-31 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS17845 b1a3f7a1738226d9e2eb14c0ddb4c5c3 925 Gene3D G3DSA:3.50.50.60 224 351 6.0E-13 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS17845 b1a3f7a1738226d9e2eb14c0ddb4c5c3 925 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 343 359 2.8E-10 T 28-03-2018 CU254_RS17845 b1a3f7a1738226d9e2eb14c0ddb4c5c3 925 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 121 140 2.8E-10 T 28-03-2018 CU254_RS17845 b1a3f7a1738226d9e2eb14c0ddb4c5c3 925 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 223 241 2.8E-10 T 28-03-2018 CU254_RS17845 b1a3f7a1738226d9e2eb14c0ddb4c5c3 925 Gene3D G3DSA:2.40.30.110 829 925 3.4E-18 T 28-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CU254_RS17845 b1a3f7a1738226d9e2eb14c0ddb4c5c3 925 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 813 912 3.5E-14 T 28-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CU254_RS17845 b1a3f7a1738226d9e2eb14c0ddb4c5c3 925 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 16 96 3.5E-21 T 28-03-2018 CU254_RS17845 b1a3f7a1738226d9e2eb14c0ddb4c5c3 925 Gene3D G3DSA:3.30.1360.120 539 673 1.1E-29 T 28-03-2018 CU254_RS17845 b1a3f7a1738226d9e2eb14c0ddb4c5c3 925 Pfam PF01571 Aminomethyltransferase folate-binding domain 544 806 1.6E-69 T 28-03-2018 IPR006222 Glycine cleavage T-protein-like, N-terminal CU254_RS17845 b1a3f7a1738226d9e2eb14c0ddb4c5c3 925 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 120 362 1.1E-15 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS08455 1efea3fab22183865827d7707c1ec52b 582 Gene3D G3DSA:3.30.930.10 25 262 1.1E-57 T 28-03-2018 CU254_RS08455 1efea3fab22183865827d7707c1ec52b 582 Gene3D G3DSA:3.30.930.10 403 471 1.1E-6 T 28-03-2018 CU254_RS08455 1efea3fab22183865827d7707c1ec52b 582 Gene3D G3DSA:3.90.960.10 263 402 1.5E-34 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CU254_RS08455 1efea3fab22183865827d7707c1ec52b 582 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 4 577 4.9E-171 T 28-03-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 CU254_RS08455 1efea3fab22183865827d7707c1ec52b 582 Hamap MF_01569 Proline--tRNA ligase [proS]. 3 581 36.903 T 28-03-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 CU254_RS08455 1efea3fab22183865827d7707c1ec52b 582 SUPERFAMILY SSF52954 477 581 4.23E-28 T 28-03-2018 IPR004154 Anticodon-binding CU254_RS08455 1efea3fab22183865827d7707c1ec52b 582 PRINTS PR01046 Prolyl-tRNA synthetase signature 136 144 2.5E-14 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CU254_RS08455 1efea3fab22183865827d7707c1ec52b 582 PRINTS PR01046 Prolyl-tRNA synthetase signature 70 88 2.5E-14 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CU254_RS08455 1efea3fab22183865827d7707c1ec52b 582 PRINTS PR01046 Prolyl-tRNA synthetase signature 146 157 2.5E-14 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CU254_RS08455 1efea3fab22183865827d7707c1ec52b 582 PRINTS PR01046 Prolyl-tRNA synthetase signature 106 117 2.5E-14 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CU254_RS08455 1efea3fab22183865827d7707c1ec52b 582 Pfam PF04073 Aminoacyl-tRNA editing domain 259 388 3.5E-21 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CU254_RS08455 1efea3fab22183865827d7707c1ec52b 582 SUPERFAMILY SSF55681 12 239 9.77E-88 T 28-03-2018 CU254_RS08455 1efea3fab22183865827d7707c1ec52b 582 SUPERFAMILY SSF55681 420 491 9.77E-88 T 28-03-2018 CU254_RS08455 1efea3fab22183865827d7707c1ec52b 582 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 96 472 3.3E-36 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CU254_RS08455 1efea3fab22183865827d7707c1ec52b 582 Gene3D G3DSA:3.40.50.800 472 582 8.9E-32 T 28-03-2018 IPR004154 Anticodon-binding CU254_RS08455 1efea3fab22183865827d7707c1ec52b 582 SUPERFAMILY SSF55826 252 383 2.35E-10 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CU254_RS08455 1efea3fab22183865827d7707c1ec52b 582 Pfam PF03129 Anticodon binding domain 490 578 6.8E-18 T 28-03-2018 IPR004154 Anticodon-binding CU254_RS20035 90dae5c202b2d4e5965f203eabf1c264 562 Gene3D G3DSA:3.10.105.10 320 532 6.6E-52 T 28-03-2018 CU254_RS20035 90dae5c202b2d4e5965f203eabf1c264 562 Gene3D G3DSA:3.90.76.10 53 212 1.1E-26 T 28-03-2018 CU254_RS20035 90dae5c202b2d4e5965f203eabf1c264 562 PIRSF PIRSF002741 3 555 8.8E-66 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CU254_RS20035 90dae5c202b2d4e5965f203eabf1c264 562 Gene3D G3DSA:3.40.190.10 213 319 2.7E-20 T 28-03-2018 CU254_RS20035 90dae5c202b2d4e5965f203eabf1c264 562 SUPERFAMILY SSF53850 41 553 1.03E-93 T 28-03-2018 CU254_RS20035 90dae5c202b2d4e5965f203eabf1c264 562 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 89 478 4.1E-68 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CU254_RS15330 bb47c688389a8dbb16ebfe5c2006d76c 372 Gene3D G3DSA:2.40.110.10 117 213 3.4E-32 T 28-03-2018 CU254_RS15330 bb47c688389a8dbb16ebfe5c2006d76c 372 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 226 366 2.4E-15 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS15330 bb47c688389a8dbb16ebfe5c2006d76c 372 SUPERFAMILY SSF56645 1 236 3.66E-62 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS15330 bb47c688389a8dbb16ebfe5c2006d76c 372 SUPERFAMILY SSF47203 263 371 4.35E-15 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS15330 bb47c688389a8dbb16ebfe5c2006d76c 372 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 214 7.2E-23 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CU254_RS15330 bb47c688389a8dbb16ebfe5c2006d76c 372 Gene3D G3DSA:1.10.540.10 1 116 4.3E-23 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS15330 bb47c688389a8dbb16ebfe5c2006d76c 372 Gene3D G3DSA:1.20.140.10 214 372 1.1E-25 T 28-03-2018 CU254_RS15330 bb47c688389a8dbb16ebfe5c2006d76c 372 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 116 7.1E-17 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS07605 849dd3e12d73a603c4333639734e4c41 812 Gene3D G3DSA:3.30.365.10 458 632 5.0E-43 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CU254_RS07605 849dd3e12d73a603c4333639734e4c41 812 SMART SM01008 23 139 1.0E-50 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CU254_RS07605 849dd3e12d73a603c4333639734e4c41 812 Gene3D G3DSA:3.30.365.10 281 442 7.9E-41 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CU254_RS07605 849dd3e12d73a603c4333639734e4c41 812 SUPERFAMILY SSF56003 131 785 9.42E-205 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CU254_RS07605 849dd3e12d73a603c4333639734e4c41 812 SUPERFAMILY SSF54665 9 160 4.06E-45 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CU254_RS07605 849dd3e12d73a603c4333639734e4c41 812 Gene3D G3DSA:3.30.365.10 176 280 1.2E-34 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CU254_RS07605 849dd3e12d73a603c4333639734e4c41 812 Gene3D G3DSA:3.90.1170.50 6 139 2.2E-38 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CU254_RS07605 849dd3e12d73a603c4333639734e4c41 812 Gene3D G3DSA:3.30.365.10 633 788 3.6E-42 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CU254_RS07605 849dd3e12d73a603c4333639734e4c41 812 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 175 722 4.9E-175 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CU254_RS07605 849dd3e12d73a603c4333639734e4c41 812 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 23 139 1.4E-27 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CU254_RS15830 e17a2492909e8cfd9e95614a49ae0764 314 Gene3D G3DSA:3.90.25.10 189 313 2.0E-38 T 28-03-2018 CU254_RS15830 e17a2492909e8cfd9e95614a49ae0764 314 SUPERFAMILY SSF51735 5 309 9.84E-82 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS15830 e17a2492909e8cfd9e95614a49ae0764 314 Pfam PF01370 NAD dependent epimerase/dehydratase family 7 239 1.6E-45 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CU254_RS15830 e17a2492909e8cfd9e95614a49ae0764 314 Gene3D G3DSA:3.40.50.720 3 188 3.7E-29 T 28-03-2018 CU254_RS11335 dc2d272e14afe4e2651c8e24184d0bb6 504 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 142 493 4.6E-38 T 28-03-2018 IPR003770 Endolytic murein transglycosylase CU254_RS11335 dc2d272e14afe4e2651c8e24184d0bb6 504 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 142 501 25.742 T 28-03-2018 IPR003770 Endolytic murein transglycosylase CU254_RS11335 dc2d272e14afe4e2651c8e24184d0bb6 504 Gene3D G3DSA:3.30.160.60 470 499 5.4E-4 T 28-03-2018 CU254_RS11335 dc2d272e14afe4e2651c8e24184d0bb6 504 Pfam PF02618 YceG-like family 178 494 2.8E-61 T 28-03-2018 IPR003770 Endolytic murein transglycosylase CU254_RS11335 dc2d272e14afe4e2651c8e24184d0bb6 504 Gene3D G3DSA:3.30.160.60 213 240 0.022 T 28-03-2018 CU254_RS16635 e636049fa6485204fae12ef25ed51298 94 SUPERFAMILY SSF54909 5 83 3.6E-17 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS16635 e636049fa6485204fae12ef25ed51298 94 Gene3D G3DSA:3.30.70.100 1 92 7.1E-17 T 28-03-2018 CU254_RS16635 e636049fa6485204fae12ef25ed51298 94 Pfam PF03992 Antibiotic biosynthesis monooxygenase 12 72 2.0E-13 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain CU254_RS38000 a77b9f5c3e939acf82f18dca470f49be 218 SUPERFAMILY SSF56281 22 214 2.57E-42 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS38000 a77b9f5c3e939acf82f18dca470f49be 218 Pfam PF00753 Metallo-beta-lactamase superfamily 33 180 2.2E-12 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS38000 a77b9f5c3e939acf82f18dca470f49be 218 SMART SM00849 32 197 2.0E-29 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS38000 a77b9f5c3e939acf82f18dca470f49be 218 Gene3D G3DSA:3.60.15.10 14 216 5.5E-33 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS06560 d099ddbce1731768fd1507aa85375597 164 Gene3D G3DSA:3.30.530.20 9 162 7.7E-28 T 28-03-2018 IPR023393 START-like domain CU254_RS06560 d099ddbce1731768fd1507aa85375597 164 SUPERFAMILY SSF55961 16 160 2.75E-42 T 28-03-2018 CU254_RS06560 d099ddbce1731768fd1507aa85375597 164 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 26 159 2.2E-25 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CU254_RS17505 d9cc1c691db310e2d62d6aee96965196 316 SMART SM00382 30 221 3.6E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS17505 d9cc1c691db310e2d62d6aee96965196 316 Gene3D G3DSA:3.40.50.300 2 283 1.8E-65 T 28-03-2018 CU254_RS17505 d9cc1c691db310e2d62d6aee96965196 316 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS17505 d9cc1c691db310e2d62d6aee96965196 316 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 13 305 6.6E-98 T 28-03-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 CU254_RS17505 d9cc1c691db310e2d62d6aee96965196 316 SUPERFAMILY SSF52540 4 227 2.24E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS17505 d9cc1c691db310e2d62d6aee96965196 316 Pfam PF00005 ABC transporter 21 164 7.0E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS29485 ed1a86c27688a8a30159c58559e332ce 77 SUPERFAMILY SSF51230 16 77 1.96E-15 T 28-03-2018 IPR011053 Single hybrid motif CU254_RS29485 ed1a86c27688a8a30159c58559e332ce 77 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 28 57 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CU254_RS29485 ed1a86c27688a8a30159c58559e332ce 77 Pfam PF00364 Biotin-requiring enzyme 17 76 2.9E-14 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CU254_RS29485 ed1a86c27688a8a30159c58559e332ce 77 Gene3D G3DSA:2.40.50.100 11 77 6.4E-15 T 28-03-2018 CU254_RS28885 4bd229ef69f0c8a80aab50b1ad20e4e2 166 Pfam PF04075 F420H(2)-dependent quinone reductase 39 130 1.4E-12 T 28-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CU254_RS28885 4bd229ef69f0c8a80aab50b1ad20e4e2 166 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 39 159 3.6E-27 T 28-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CU254_RS28885 4bd229ef69f0c8a80aab50b1ad20e4e2 166 Gene3D G3DSA:2.30.110.10 18 160 5.3E-23 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS06785 8d482decf44827cca3e27b234946b2db 719 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 428 456 1.3E-8 T 28-03-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 CU254_RS06785 8d482decf44827cca3e27b234946b2db 719 Pfam PF12826 Helix-hairpin-helix motif 539 601 2.9E-22 T 28-03-2018 CU254_RS06785 8d482decf44827cca3e27b234946b2db 719 SMART SM00532 25 470 1.0E-244 T 28-03-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 CU254_RS06785 8d482decf44827cca3e27b234946b2db 719 Gene3D G3DSA:1.10.150.20 534 599 1.9E-27 T 28-03-2018 CU254_RS06785 8d482decf44827cca3e27b234946b2db 719 Hamap MF_01588 DNA ligase [ligA]. 24 694 50.191 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CU254_RS06785 8d482decf44827cca3e27b234946b2db 719 SUPERFAMILY SSF52113 623 697 2.06E-17 T 28-03-2018 IPR001357 BRCT domain CU254_RS06785 8d482decf44827cca3e27b234946b2db 719 Gene3D G3DSA:3.40.50.10190 600 697 9.2E-20 T 28-03-2018 IPR001357 BRCT domain CU254_RS06785 8d482decf44827cca3e27b234946b2db 719 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 27 339 5.9E-118 T 28-03-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 CU254_RS06785 8d482decf44827cca3e27b234946b2db 719 Gene3D G3DSA:1.10.150.20 454 533 5.4E-21 T 28-03-2018 CU254_RS06785 8d482decf44827cca3e27b234946b2db 719 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 343 419 6.5E-29 T 28-03-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 CU254_RS06785 8d482decf44827cca3e27b234946b2db 719 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 134 163 - T 28-03-2018 IPR018239 NAD-dependent DNA ligase, active site CU254_RS06785 8d482decf44827cca3e27b234946b2db 719 PIRSF PIRSF001604 19 698 2.8E-231 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CU254_RS06785 8d482decf44827cca3e27b234946b2db 719 Gene3D G3DSA:2.40.50.140 343 410 7.2E-27 T 28-03-2018 CU254_RS06785 8d482decf44827cca3e27b234946b2db 719 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 623 693 9.2E-13 T 28-03-2018 IPR001357 BRCT domain CU254_RS06785 8d482decf44827cca3e27b234946b2db 719 Gene3D G3DSA:1.10.287.610 16 88 3.1E-23 T 28-03-2018 CU254_RS06785 8d482decf44827cca3e27b234946b2db 719 SUPERFAMILY SSF47781 424 612 3.08E-48 T 28-03-2018 IPR010994 RuvA domain 2-like CU254_RS06785 8d482decf44827cca3e27b234946b2db 719 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 33 689 1.8E-235 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CU254_RS06785 8d482decf44827cca3e27b234946b2db 719 SUPERFAMILY SSF56091 24 339 1.92E-111 T 28-03-2018 CU254_RS06785 8d482decf44827cca3e27b234946b2db 719 Gene3D G3DSA:3.30.1490.70 103 182 1.1E-20 T 28-03-2018 CU254_RS06785 8d482decf44827cca3e27b234946b2db 719 SMART SM00292 620 697 1.1E-14 T 28-03-2018 IPR001357 BRCT domain CU254_RS06785 8d482decf44827cca3e27b234946b2db 719 Gene3D G3DSA:3.30.1490.70 220 342 1.9E-28 T 28-03-2018 CU254_RS06785 8d482decf44827cca3e27b234946b2db 719 SUPERFAMILY SSF50249 338 421 3.94E-25 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CU254_RS06355 3f969427edf9441b34065f9262d19c8b 320 Gene3D G3DSA:1.20.5.170 5 45 1.4E-6 T 28-03-2018 CU254_RS06355 3f969427edf9441b34065f9262d19c8b 320 SMART SM00382 48 192 0.0033 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS06355 3f969427edf9441b34065f9262d19c8b 320 Gene3D G3DSA:3.40.50.300 47 256 4.8E-42 T 28-03-2018 CU254_RS06355 3f969427edf9441b34065f9262d19c8b 320 Pfam PF03308 ArgK protein 22 283 4.7E-98 T 28-03-2018 CU254_RS06355 3f969427edf9441b34065f9262d19c8b 320 SUPERFAMILY SSF52540 4 316 3.43E-82 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS06355 3f969427edf9441b34065f9262d19c8b 320 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 16 314 1.7E-105 T 28-03-2018 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CU254_RS19100 ef985a8e038dee7388ad1e2b6853574a 832 Gene3D G3DSA:3.40.50.300 649 810 1.4E-37 T 28-03-2018 CU254_RS19100 ef985a8e038dee7388ad1e2b6853574a 832 SMART SM00490 690 772 4.8E-22 T 28-03-2018 IPR001650 Helicase, C-terminal CU254_RS19100 ef985a8e038dee7388ad1e2b6853574a 832 SUPERFAMILY SSF52540 355 575 3.4E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS19100 ef985a8e038dee7388ad1e2b6853574a 832 Pfam PF00271 Helicase conserved C-terminal domain 661 772 2.7E-16 T 28-03-2018 IPR001650 Helicase, C-terminal CU254_RS19100 ef985a8e038dee7388ad1e2b6853574a 832 Pfam PF12419 SNF2 Helicase protein 205 328 3.7E-29 T 28-03-2018 IPR022138 Helicase SWF/SNF-related CU254_RS19100 ef985a8e038dee7388ad1e2b6853574a 832 Gene3D G3DSA:3.40.50.10810 348 579 1.7E-43 T 28-03-2018 CU254_RS19100 ef985a8e038dee7388ad1e2b6853574a 832 SUPERFAMILY SSF52540 582 828 2.13E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS19100 ef985a8e038dee7388ad1e2b6853574a 832 Pfam PF00176 SNF2 family N-terminal domain 391 644 5.8E-46 T 28-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 CU254_RS19100 ef985a8e038dee7388ad1e2b6853574a 832 SMART SM00487 368 547 2.2E-26 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CU254_RS27885 188bf329ed655640e84554576277442c 743 Pfam PF00403 Heavy-metal-associated domain 14 72 5.8E-12 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CU254_RS27885 188bf329ed655640e84554576277442c 743 SUPERFAMILY SSF81665 336 429 1.83E-13 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CU254_RS27885 188bf329ed655640e84554576277442c 743 SUPERFAMILY SSF81665 684 712 1.83E-13 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CU254_RS27885 188bf329ed655640e84554576277442c 743 SUPERFAMILY SSF81665 205 239 1.83E-13 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CU254_RS27885 188bf329ed655640e84554576277442c 743 Gene3D G3DSA:3.40.1110.10 451 562 1.0E-33 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CU254_RS27885 188bf329ed655640e84554576277442c 743 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 209 717 4.9E-87 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CU254_RS27885 188bf329ed655640e84554576277442c 743 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 200 738 1.0E-149 T 28-03-2018 CU254_RS27885 188bf329ed655640e84554576277442c 743 ProSitePatterns PS01229 Hypothetical cof family signature 2. 635 657 - T 28-03-2018 CU254_RS27885 188bf329ed655640e84554576277442c 743 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 437 443 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CU254_RS27885 188bf329ed655640e84554576277442c 743 Pfam PF00702 haloacid dehalogenase-like hydrolase 431 649 6.3E-46 T 28-03-2018 CU254_RS27885 188bf329ed655640e84554576277442c 743 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 154 737 1.6E-176 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CU254_RS27885 188bf329ed655640e84554576277442c 743 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 607 623 1.8E-7 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CU254_RS27885 188bf329ed655640e84554576277442c 743 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 635 651 1.8E-7 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CU254_RS27885 188bf329ed655640e84554576277442c 743 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 666 691 1.8E-7 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CU254_RS27885 188bf329ed655640e84554576277442c 743 Gene3D G3DSA:3.40.50.1000 563 700 4.3E-37 T 28-03-2018 IPR023214 HAD-like domain CU254_RS27885 188bf329ed655640e84554576277442c 743 Gene3D G3DSA:3.30.70.100 9 94 1.1E-19 T 28-03-2018 CU254_RS27885 188bf329ed655640e84554576277442c 743 Pfam PF00122 E1-E2 ATPase 238 413 5.4E-54 T 28-03-2018 CU254_RS27885 188bf329ed655640e84554576277442c 743 Gene3D G3DSA:1.20.1110.10 199 450 6.0E-46 T 28-03-2018 CU254_RS27885 188bf329ed655640e84554576277442c 743 SUPERFAMILY SSF55008 6 79 4.58E-19 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CU254_RS27885 188bf329ed655640e84554576277442c 743 SUPERFAMILY SSF56784 507 735 1.4E-54 T 28-03-2018 IPR023214 HAD-like domain CU254_RS27885 188bf329ed655640e84554576277442c 743 SUPERFAMILY SSF56784 433 453 1.4E-54 T 28-03-2018 IPR023214 HAD-like domain CU254_RS27885 188bf329ed655640e84554576277442c 743 ProSitePatterns PS01047 Heavy-metal-associated domain. 16 44 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CU254_RS27885 188bf329ed655640e84554576277442c 743 SUPERFAMILY SSF81653 241 335 3.14E-25 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CU254_RS27885 188bf329ed655640e84554576277442c 743 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 285 299 1.8E-22 T 28-03-2018 CU254_RS27885 188bf329ed655640e84554576277442c 743 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 635 654 1.8E-22 T 28-03-2018 CU254_RS27885 188bf329ed655640e84554576277442c 743 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 658 670 1.8E-22 T 28-03-2018 CU254_RS27885 188bf329ed655640e84554576277442c 743 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 435 449 1.8E-22 T 28-03-2018 CU254_RS27885 188bf329ed655640e84554576277442c 743 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 582 592 1.8E-22 T 28-03-2018 CU254_RS11570 0cce3229641f529aa5fb87ae19e59703 308 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 1 300 5.5E-66 T 28-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 CU254_RS11570 0cce3229641f529aa5fb87ae19e59703 308 Gene3D G3DSA:3.10.25.10 207 308 2.6E-25 T 28-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CU254_RS11570 0cce3229641f529aa5fb87ae19e59703 308 Gene3D G3DSA:3.40.50.170 1 206 4.7E-60 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CU254_RS11570 0cce3229641f529aa5fb87ae19e59703 308 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 1 302 31.817 T 28-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 CU254_RS11570 0cce3229641f529aa5fb87ae19e59703 308 SUPERFAMILY SSF53328 1 206 7.72E-56 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CU254_RS11570 0cce3229641f529aa5fb87ae19e59703 308 Pfam PF02911 Formyl transferase, C-terminal domain 204 299 1.1E-20 T 28-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CU254_RS11570 0cce3229641f529aa5fb87ae19e59703 308 Pfam PF00551 Formyl transferase 2 180 8.0E-33 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CU254_RS11570 0cce3229641f529aa5fb87ae19e59703 308 SUPERFAMILY SSF50486 206 307 1.57E-23 T 28-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 CU254_RS02160 f39e79cce05f848bfb191ffae1fbebeb 466 Pfam PF08817 WXG100 protein secretion system (Wss), protein YukD 9 84 4.9E-23 T 28-03-2018 IPR024962 YukD-like CU254_RS02160 f39e79cce05f848bfb191ffae1fbebeb 466 TIGRFAM TIGR03920 T7SS_EccD: type VII secretion integral membrane protein EccD 11 462 1.8E-91 T 28-03-2018 IPR006707 Type VII secretion system membrane protein EccD CU254_RS02160 f39e79cce05f848bfb191ffae1fbebeb 466 PIRSF PIRSF017804 1 465 2.4E-114 T 28-03-2018 IPR006707 Type VII secretion system membrane protein EccD CU254_RS30830 c7a35c40a48f0fd80b70d083724fd2bc 188 Gene3D G3DSA:1.10.260.40 4 80 4.3E-10 T 28-03-2018 CU254_RS30830 c7a35c40a48f0fd80b70d083724fd2bc 188 SUPERFAMILY SSF47413 8 72 5.94E-7 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS30830 c7a35c40a48f0fd80b70d083724fd2bc 188 Pfam PF13560 Helix-turn-helix domain 11 73 1.5E-6 T 28-03-2018 CU254_RS18735 e6f94039e143b751ebc711b45c73ba73 199 Gene3D G3DSA:1.10.10.60 8 42 1.8E-13 T 28-03-2018 CU254_RS18735 e6f94039e143b751ebc711b45c73ba73 199 Gene3D G3DSA:1.10.260.40 43 72 1.2E-10 T 28-03-2018 CU254_RS18735 e6f94039e143b751ebc711b45c73ba73 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 9.2E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS18735 e6f94039e143b751ebc711b45c73ba73 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 9.2E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS18735 e6f94039e143b751ebc711b45c73ba73 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 67 3.4E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS18735 e6f94039e143b751ebc711b45c73ba73 199 SUPERFAMILY SSF46689 15 91 2.19E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS18735 e6f94039e143b751ebc711b45c73ba73 199 Gene3D G3DSA:1.10.357.10 73 199 4.4E-4 T 28-03-2018 CU254_RS07830 19ca5234fd8591d46ea112631cd6f8ac 296 Pfam PF01014 Uricase 9 132 8.8E-21 T 28-03-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CU254_RS07830 19ca5234fd8591d46ea112631cd6f8ac 296 Pfam PF01014 Uricase 142 276 9.7E-36 T 28-03-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CU254_RS07830 19ca5234fd8591d46ea112631cd6f8ac 296 SUPERFAMILY SSF55620 5 134 5.17E-46 T 28-03-2018 CU254_RS07830 19ca5234fd8591d46ea112631cd6f8ac 296 PRINTS PR00093 Uricase signature 86 99 4.2E-20 T 28-03-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CU254_RS07830 19ca5234fd8591d46ea112631cd6f8ac 296 PRINTS PR00093 Uricase signature 148 164 4.2E-20 T 28-03-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CU254_RS07830 19ca5234fd8591d46ea112631cd6f8ac 296 PRINTS PR00093 Uricase signature 50 64 4.2E-20 T 28-03-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CU254_RS07830 19ca5234fd8591d46ea112631cd6f8ac 296 PRINTS PR00093 Uricase signature 164 176 4.2E-20 T 28-03-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CU254_RS07830 19ca5234fd8591d46ea112631cd6f8ac 296 PRINTS PR00093 Uricase signature 11 22 4.2E-20 T 28-03-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CU254_RS07830 19ca5234fd8591d46ea112631cd6f8ac 296 SUPERFAMILY SSF55620 139 292 1.08E-57 T 28-03-2018 CU254_RS07830 19ca5234fd8591d46ea112631cd6f8ac 296 ProSitePatterns PS00366 Uricase signature. 148 175 - T 28-03-2018 IPR019842 Uricase, conserved site GO:0004846|GO:0006144|GO:0055114 KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CU254_RS07830 19ca5234fd8591d46ea112631cd6f8ac 296 PIRSF PIRSF000241 2 287 6.7E-101 T 28-03-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CU254_RS07830 19ca5234fd8591d46ea112631cd6f8ac 296 Gene3D G3DSA:3.10.270.10 1 286 2.3E-118 T 28-03-2018 CU254_RS07830 19ca5234fd8591d46ea112631cd6f8ac 296 ProDom PD003367 URICASE OXIDOREDUCTASE URATE OXIDASE METABOLISM PURINE PEROXISOME ACETYLATION II DIRECT 178 281 7.0E-34 T 28-03-2018 CU254_RS07830 19ca5234fd8591d46ea112631cd6f8ac 296 TIGRFAM TIGR03383 urate_oxi: urate oxidase 6 281 2.8E-109 T 28-03-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CU254_RS10295 a5539cab89989399e30332924e0a92fe 666 Gene3D G3DSA:1.10.540.10 1 109 2.2E-6 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS10295 a5539cab89989399e30332924e0a92fe 666 SUPERFAMILY SSF56645 343 541 3.27E-58 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS10295 a5539cab89989399e30332924e0a92fe 666 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 184 304 2.6E-21 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS10295 a5539cab89989399e30332924e0a92fe 666 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 528 662 8.8E-6 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS10295 a5539cab89989399e30332924e0a92fe 666 SUPERFAMILY SSF56645 1 140 3.14E-8 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS10295 a5539cab89989399e30332924e0a92fe 666 SUPERFAMILY SSF47203 181 310 2.26E-30 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS10295 a5539cab89989399e30332924e0a92fe 666 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 422 515 4.9E-20 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CU254_RS10295 a5539cab89989399e30332924e0a92fe 666 Gene3D G3DSA:1.20.140.10 176 325 9.9E-30 T 28-03-2018 CU254_RS10295 a5539cab89989399e30332924e0a92fe 666 SUPERFAMILY SSF47203 528 664 6.44E-8 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS10295 a5539cab89989399e30332924e0a92fe 666 Gene3D G3DSA:1.10.540.10 326 418 1.0E-14 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS10295 a5539cab89989399e30332924e0a92fe 666 Gene3D G3DSA:2.40.110.10 419 515 2.3E-34 T 28-03-2018 CU254_RS10295 a5539cab89989399e30332924e0a92fe 666 Gene3D G3DSA:1.20.140.10 516 666 6.3E-20 T 28-03-2018 CU254_RS10295 a5539cab89989399e30332924e0a92fe 666 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 333 418 2.0E-8 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS39105 f061ef3326e34aa8c08dcba9a8a009e3 465 Pfam PF14021 Tuberculosis necrotizing toxin 380 464 2.7E-14 T 28-03-2018 IPR025331 Tuberculosis necrotizing toxin CU254_RS39105 f061ef3326e34aa8c08dcba9a8a009e3 465 SUPERFAMILY SSF160424 61 135 1.27E-12 T 28-03-2018 IPR006728 Protein of unknown function DUF600 CU254_RS10820 cd740890283e42b9411e4633db955dbb 323 Gene3D G3DSA:3.90.1200.10 123 292 1.4E-16 T 28-03-2018 CU254_RS10820 cd740890283e42b9411e4633db955dbb 323 Pfam PF01636 Phosphotransferase enzyme family 39 254 1.8E-20 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CU254_RS10820 cd740890283e42b9411e4633db955dbb 323 SUPERFAMILY SSF56112 16 272 3.35E-24 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS10820 cd740890283e42b9411e4633db955dbb 323 Gene3D G3DSA:3.30.200.20 17 117 2.1E-7 T 28-03-2018 CU254_RS02030 33b13e39985cccd74759f7275adbadc0 133 SUPERFAMILY SSF53137 20 131 6.11E-48 T 28-03-2018 CU254_RS02030 33b13e39985cccd74759f7275adbadc0 133 Gene3D G3DSA:3.30.420.100 14 133 1.5E-39 T 28-03-2018 CU254_RS02030 33b13e39985cccd74759f7275adbadc0 133 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 19 133 2.6E-48 T 28-03-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS02030 33b13e39985cccd74759f7275adbadc0 133 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 22 133 5.5E-41 T 28-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS02030 33b13e39985cccd74759f7275adbadc0 133 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 19 133 27.106 T 28-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS15425 9512239aed5a72b77d9a19c4a5a9e6b3 139 Pfam PF00571 CBS domain 4 55 1.4E-13 T 28-03-2018 IPR000644 CBS domain CU254_RS15425 9512239aed5a72b77d9a19c4a5a9e6b3 139 Pfam PF00571 CBS domain 77 124 1.2E-10 T 28-03-2018 IPR000644 CBS domain CU254_RS15425 9512239aed5a72b77d9a19c4a5a9e6b3 139 SUPERFAMILY SSF54631 2 124 5.94E-33 T 28-03-2018 CU254_RS15425 9512239aed5a72b77d9a19c4a5a9e6b3 139 SMART SM00116 77 124 2.6E-11 T 28-03-2018 IPR000644 CBS domain CU254_RS15425 9512239aed5a72b77d9a19c4a5a9e6b3 139 SMART SM00116 11 59 1.3E-8 T 28-03-2018 IPR000644 CBS domain CU254_RS15425 9512239aed5a72b77d9a19c4a5a9e6b3 139 Gene3D G3DSA:3.10.580.10 1 126 3.4E-32 T 28-03-2018 CU254_RS14425 d8ec84f087c2dc9bb1021a55f052d960 344 SUPERFAMILY SSF56322 56 339 5.23E-89 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CU254_RS14425 d8ec84f087c2dc9bb1021a55f052d960 344 PRINTS PR00095 Anthranilate synthase component I signature 287 301 8.4E-5 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CU254_RS14425 d8ec84f087c2dc9bb1021a55f052d960 344 PRINTS PR00095 Anthranilate synthase component I signature 272 286 8.4E-5 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CU254_RS14425 d8ec84f087c2dc9bb1021a55f052d960 344 PRINTS PR00095 Anthranilate synthase component I signature 179 192 8.4E-5 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CU254_RS14425 d8ec84f087c2dc9bb1021a55f052d960 344 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 65 338 1.2E-79 T 28-03-2018 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 CU254_RS14425 d8ec84f087c2dc9bb1021a55f052d960 344 Pfam PF00425 chorismate binding enzyme 71 330 2.2E-72 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal CU254_RS14425 d8ec84f087c2dc9bb1021a55f052d960 344 Gene3D G3DSA:3.60.120.10 9 341 1.1E-92 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CU254_RS04095 d1725deaf218223bc919c890c7d429e6 1124 Gene3D G3DSA:1.10.486.10 473 643 2.3E-30 T 28-03-2018 CU254_RS04095 d1725deaf218223bc919c890c7d429e6 1124 Gene3D G3DSA:3.40.50.300 16 356 1.6E-44 T 28-03-2018 CU254_RS04095 d1725deaf218223bc919c890c7d429e6 1124 Pfam PF13361 UvrD-like helicase C-terminal domain 362 766 4.1E-25 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CU254_RS04095 d1725deaf218223bc919c890c7d429e6 1124 Pfam PF00580 UvrD/REP helicase N-terminal domain 25 344 9.1E-47 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CU254_RS04095 d1725deaf218223bc919c890c7d429e6 1124 Gene3D G3DSA:3.40.50.300 362 472 3.2E-10 T 28-03-2018 CU254_RS04095 d1725deaf218223bc919c890c7d429e6 1124 SUPERFAMILY SSF52540 547 697 1.34E-104 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS04095 d1725deaf218223bc919c890c7d429e6 1124 SUPERFAMILY SSF52540 22 200 1.34E-104 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS04095 d1725deaf218223bc919c890c7d429e6 1124 SUPERFAMILY SSF52540 232 513 1.34E-104 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS04095 d1725deaf218223bc919c890c7d429e6 1124 SUPERFAMILY SSF52540 745 793 1.34E-104 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS04095 d1725deaf218223bc919c890c7d429e6 1124 Gene3D G3DSA:3.90.320.10 684 1099 1.4E-18 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 CU254_RS04095 d1725deaf218223bc919c890c7d429e6 1124 Pfam PF12705 PD-(D/E)XK nuclease superfamily 962 1099 1.2E-11 T 28-03-2018 CU254_RS04095 d1725deaf218223bc919c890c7d429e6 1124 SUPERFAMILY SSF52980 932 1099 1.34E-6 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CU254_RS32295 ea95b3452aa7f8518c08ec3835b879fe 540 Pfam PF05199 GMC oxidoreductase 476 527 7.6E-13 T 28-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 CU254_RS32295 ea95b3452aa7f8518c08ec3835b879fe 540 SUPERFAMILY SSF51905 45 347 1.5E-38 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS32295 ea95b3452aa7f8518c08ec3835b879fe 540 SUPERFAMILY SSF51905 478 534 1.5E-38 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS32295 ea95b3452aa7f8518c08ec3835b879fe 540 Gene3D G3DSA:3.30.410.10 318 473 1.5E-67 T 28-03-2018 CU254_RS32295 ea95b3452aa7f8518c08ec3835b879fe 540 Gene3D G3DSA:3.30.410.10 193 276 8.4E-16 T 28-03-2018 CU254_RS32295 ea95b3452aa7f8518c08ec3835b879fe 540 ProSitePatterns PS00623 GMC oxidoreductases signature 1. 141 164 - T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CU254_RS32295 ea95b3452aa7f8518c08ec3835b879fe 540 SUPERFAMILY SSF54373 351 481 2.16E-54 T 28-03-2018 CU254_RS32295 ea95b3452aa7f8518c08ec3835b879fe 540 Pfam PF00732 GMC oxidoreductase 136 332 5.9E-5 T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CU254_RS40780 17556f3d40daa43eedb8cbce65865b1f 101 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 93 18.254 T 28-03-2018 IPR003482 Transcription factor WhiB CU254_RS40780 17556f3d40daa43eedb8cbce65865b1f 101 Pfam PF02467 Transcription factor WhiB 17 87 5.0E-23 T 28-03-2018 IPR034768 WhiB-like iron-sulfur binding domain CU254_RS07775 4e96a0421353f448ac2106addba29eba 254 Pfam PF01614 Bacterial transcriptional regulator 127 249 1.3E-29 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal CU254_RS07775 4e96a0421353f448ac2106addba29eba 254 SUPERFAMILY SSF55781 69 251 3.47E-48 T 28-03-2018 IPR029016 GAF domain-like CU254_RS07775 4e96a0421353f448ac2106addba29eba 254 SUPERFAMILY SSF46785 12 81 7.58E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS07775 4e96a0421353f448ac2106addba29eba 254 Pfam PF09339 IclR helix-turn-helix domain 14 64 2.9E-18 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS07775 4e96a0421353f448ac2106addba29eba 254 Gene3D G3DSA:3.30.450.40 81 254 1.4E-51 T 28-03-2018 IPR029016 GAF domain-like CU254_RS07775 4e96a0421353f448ac2106addba29eba 254 Gene3D G3DSA:1.10.10.10 1 72 6.3E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS07775 4e96a0421353f448ac2106addba29eba 254 SMART SM00346 12 99 1.2E-20 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS12480 a62bcb7f5520a5803b7efdd451c0bbd7 464 Gene3D G3DSA:1.20.1250.20 8 202 1.7E-27 T 28-03-2018 CU254_RS12480 a62bcb7f5520a5803b7efdd451c0bbd7 464 SUPERFAMILY SSF103473 6 199 1.31E-58 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS12480 a62bcb7f5520a5803b7efdd451c0bbd7 464 SUPERFAMILY SSF103473 250 463 1.31E-58 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS12480 a62bcb7f5520a5803b7efdd451c0bbd7 464 Pfam PF07690 Major Facilitator Superfamily 20 413 1.6E-42 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS12480 a62bcb7f5520a5803b7efdd451c0bbd7 464 Gene3D G3DSA:1.20.1250.20 252 464 6.8E-24 T 28-03-2018 CU254_RS04750 c810ff05a56a2174ca98b366ba4c848d 699 SMART SM00341 623 699 2.7E-9 T 28-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 CU254_RS04750 c810ff05a56a2174ca98b366ba4c848d 699 Gene3D G3DSA:1.10.150.80 608 699 7.2E-22 T 28-03-2018 CU254_RS04750 c810ff05a56a2174ca98b366ba4c848d 699 SUPERFAMILY SSF47819 617 696 6.32E-21 T 28-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 CU254_RS04750 c810ff05a56a2174ca98b366ba4c848d 699 Pfam PF13361 UvrD-like helicase C-terminal domain 446 555 2.0E-21 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CU254_RS04750 c810ff05a56a2174ca98b366ba4c848d 699 Pfam PF13361 UvrD-like helicase C-terminal domain 290 414 3.5E-18 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CU254_RS04750 c810ff05a56a2174ca98b366ba4c848d 699 Gene3D G3DSA:3.40.50.300 287 580 9.9E-58 T 28-03-2018 CU254_RS04750 c810ff05a56a2174ca98b366ba4c848d 699 Gene3D G3DSA:3.40.50.300 12 286 6.7E-51 T 28-03-2018 CU254_RS04750 c810ff05a56a2174ca98b366ba4c848d 699 Pfam PF00580 UvrD/REP helicase N-terminal domain 20 283 1.6E-47 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CU254_RS04750 c810ff05a56a2174ca98b366ba4c848d 699 SUPERFAMILY SSF52540 15 577 2.9E-130 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS04750 c810ff05a56a2174ca98b366ba4c848d 699 Pfam PF00570 HRDC domain 627 693 5.7E-20 T 28-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 CU254_RS02805 62887cc27375afbe53a640e8d8ff4222 584 SUPERFAMILY SSF46977 447 584 2.09E-49 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CU254_RS02805 62887cc27375afbe53a640e8d8ff4222 584 Gene3D G3DSA:1.20.58.100 426 535 9.4E-34 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CU254_RS02805 62887cc27375afbe53a640e8d8ff4222 584 SUPERFAMILY SSF51905 2 260 1.15E-73 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS02805 62887cc27375afbe53a640e8d8ff4222 584 SUPERFAMILY SSF51905 359 436 1.15E-73 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS02805 62887cc27375afbe53a640e8d8ff4222 584 PIRSF PIRSF000171 1 575 1.9E-47 T 28-03-2018 CU254_RS02805 62887cc27375afbe53a640e8d8ff4222 584 Pfam PF00890 FAD binding domain 7 401 1.8E-111 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CU254_RS02805 62887cc27375afbe53a640e8d8ff4222 584 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 7 584 1.7E-251 T 28-03-2018 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CU254_RS02805 62887cc27375afbe53a640e8d8ff4222 584 SUPERFAMILY SSF56425 237 355 8.22E-43 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CU254_RS02805 62887cc27375afbe53a640e8d8ff4222 584 Pfam PF02910 Fumarate reductase flavoprotein C-term 455 584 2.9E-45 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CU254_RS02805 62887cc27375afbe53a640e8d8ff4222 584 TIGRFAM TIGR01816 sdhA_forward: succinate dehydrogenase, flavoprotein subunit 4 584 4.5E-291 T 28-03-2018 IPR011281 Succinate dehydrogenase, flavoprotein subunit GO:0006099|GO:0016627|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CU254_RS02805 62887cc27375afbe53a640e8d8ff4222 584 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 40 49 - T 28-03-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CU254_RS02805 62887cc27375afbe53a640e8d8ff4222 584 Gene3D G3DSA:4.10.80.40 536 584 1.6E-19 T 28-03-2018 CU254_RS02805 62887cc27375afbe53a640e8d8ff4222 584 Gene3D G3DSA:3.50.50.60 3 306 3.0E-46 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS02805 62887cc27375afbe53a640e8d8ff4222 584 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 379 386 1.1E-5 T 28-03-2018 CU254_RS02805 62887cc27375afbe53a640e8d8ff4222 584 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 1.1E-5 T 28-03-2018 CU254_RS02805 62887cc27375afbe53a640e8d8ff4222 584 Gene3D G3DSA:3.50.50.60 310 417 1.0E-19 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS23845 99966ead3d945729bf8dffc02f1b38ba 473 Gene3D G3DSA:3.40.50.1220 300 473 9.5E-87 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CU254_RS23845 99966ead3d945729bf8dffc02f1b38ba 473 PIRSF PIRSF000204 3 473 6.2E-209 T 28-03-2018 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2 CU254_RS23845 99966ead3d945729bf8dffc02f1b38ba 473 Pfam PF02233 NAD(P) transhydrogenase beta subunit 9 471 3.7E-194 T 28-03-2018 IPR034300 NADP transhydrogenase beta-like domain KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 CU254_RS23845 99966ead3d945729bf8dffc02f1b38ba 473 SUPERFAMILY SSF52467 300 473 7.85E-74 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CU254_RS08920 385cf50b00e739449dd20e600d655a96 94 Gene3D G3DSA:3.30.70.920 1 85 1.2E-17 T 28-03-2018 CU254_RS08920 385cf50b00e739449dd20e600d655a96 94 Pfam PF01037 Lrp/AsnC ligand binding domain 6 76 5.9E-14 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CU254_RS08920 385cf50b00e739449dd20e600d655a96 94 SUPERFAMILY SSF54909 2 77 6.57E-17 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS14645 071a5439b979e53b871dddcf8d4e1192 294 SUPERFAMILY SSF51445 20 152 4.84E-9 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS14645 071a5439b979e53b871dddcf8d4e1192 294 Pfam PF08924 Domain of unknown function (DUF1906) 15 130 1.4E-19 T 28-03-2018 IPR015020 Protein of unknown function DUF1906 CU254_RS14645 071a5439b979e53b871dddcf8d4e1192 294 Gene3D G3DSA:3.20.20.80 10 192 6.7E-17 T 28-03-2018 CU254_RS16475 7b630dc15f14482da9516fc3052416f5 329 Pfam PF00561 alpha/beta hydrolase fold 69 156 2.3E-20 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS16475 7b630dc15f14482da9516fc3052416f5 329 PRINTS PR00412 Epoxide hydrolase signature 138 151 1.3E-9 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS16475 7b630dc15f14482da9516fc3052416f5 329 PRINTS PR00412 Epoxide hydrolase signature 304 326 1.3E-9 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS16475 7b630dc15f14482da9516fc3052416f5 329 PRINTS PR00412 Epoxide hydrolase signature 74 92 1.3E-9 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS16475 7b630dc15f14482da9516fc3052416f5 329 SUPERFAMILY SSF53474 43 328 1.54E-60 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS16475 7b630dc15f14482da9516fc3052416f5 329 Gene3D G3DSA:3.40.50.1820 35 329 4.1E-44 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS20340 798b4aee2561b642da8bd0c8c7dfccc5 562 Gene3D G3DSA:1.20.1250.20 10 217 7.2E-21 T 28-03-2018 CU254_RS20340 798b4aee2561b642da8bd0c8c7dfccc5 562 SUPERFAMILY SSF103473 17 219 2.35E-47 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS20340 798b4aee2561b642da8bd0c8c7dfccc5 562 SUPERFAMILY SSF103473 531 557 2.35E-47 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS20340 798b4aee2561b642da8bd0c8c7dfccc5 562 SUPERFAMILY SSF103473 271 449 2.35E-47 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS20340 798b4aee2561b642da8bd0c8c7dfccc5 562 Gene3D G3DSA:1.20.1250.20 281 557 1.4E-25 T 28-03-2018 CU254_RS20340 798b4aee2561b642da8bd0c8c7dfccc5 562 Pfam PF07690 Major Facilitator Superfamily 25 439 1.5E-41 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS08485 a5a85816d977f73a779a46cbf0549246 417 Pfam PF13796 Putative sensor 24 199 6.7E-27 T 28-03-2018 IPR025828 Putative sensor domain CU254_RS08485 a5a85816d977f73a779a46cbf0549246 417 Gene3D G3DSA:3.30.565.10 206 416 9.2E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS08485 a5a85816d977f73a779a46cbf0549246 417 SUPERFAMILY SSF55874 307 415 2.46E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS08485 a5a85816d977f73a779a46cbf0549246 417 Pfam PF07730 Histidine kinase 228 296 2.2E-11 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CU254_RS36670 7cf9b50d3b4701dc9bd01decffd0f8ee 609 Pfam PF00117 Glutamine amidotransferase class-I 407 586 8.1E-23 T 28-03-2018 IPR017926 Glutamine amidotransferase CU254_RS36670 7cf9b50d3b4701dc9bd01decffd0f8ee 609 PRINTS PR00096 Glutamine amidotransferase superfamily signature 566 579 1.7E-7 T 28-03-2018 CU254_RS36670 7cf9b50d3b4701dc9bd01decffd0f8ee 609 PRINTS PR00096 Glutamine amidotransferase superfamily signature 479 490 1.7E-7 T 28-03-2018 CU254_RS36670 7cf9b50d3b4701dc9bd01decffd0f8ee 609 PRINTS PR00096 Glutamine amidotransferase superfamily signature 446 455 1.7E-7 T 28-03-2018 CU254_RS36670 7cf9b50d3b4701dc9bd01decffd0f8ee 609 SUPERFAMILY SSF52317 400 589 7.92E-25 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS36670 7cf9b50d3b4701dc9bd01decffd0f8ee 609 Pfam PF00425 chorismate binding enzyme 83 342 5.6E-45 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal CU254_RS36670 7cf9b50d3b4701dc9bd01decffd0f8ee 609 PRINTS PR00097 Anthranilate synthase component II signature 566 579 3.3E-9 T 28-03-2018 CU254_RS36670 7cf9b50d3b4701dc9bd01decffd0f8ee 609 PRINTS PR00097 Anthranilate synthase component II signature 405 419 3.3E-9 T 28-03-2018 CU254_RS36670 7cf9b50d3b4701dc9bd01decffd0f8ee 609 PRINTS PR00097 Anthranilate synthase component II signature 446 455 3.3E-9 T 28-03-2018 CU254_RS36670 7cf9b50d3b4701dc9bd01decffd0f8ee 609 SUPERFAMILY SSF56322 40 350 7.46E-61 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CU254_RS36670 7cf9b50d3b4701dc9bd01decffd0f8ee 609 Gene3D G3DSA:3.60.120.10 2 353 3.0E-71 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CU254_RS36670 7cf9b50d3b4701dc9bd01decffd0f8ee 609 Gene3D G3DSA:3.40.50.880 403 592 1.4E-33 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS36115 2020c1384b8cc7ab875d838c7259f949 278 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS36115 2020c1384b8cc7ab875d838c7259f949 278 Pfam PF00005 ABC transporter 29 173 1.4E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS36115 2020c1384b8cc7ab875d838c7259f949 278 Gene3D G3DSA:3.40.50.300 8 275 4.0E-50 T 28-03-2018 CU254_RS36115 2020c1384b8cc7ab875d838c7259f949 278 SMART SM00382 36 223 5.6E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS36115 2020c1384b8cc7ab875d838c7259f949 278 SUPERFAMILY SSF52540 11 236 9.63E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS10575 67ad868ad9581cb5163d4ede1f7c046b 327 Gene3D G3DSA:2.40.50.140 70 138 5.0E-18 T 28-03-2018 CU254_RS10575 67ad868ad9581cb5163d4ede1f7c046b 327 Gene3D G3DSA:2.40.50.140 233 300 3.0E-17 T 28-03-2018 CU254_RS10575 67ad868ad9581cb5163d4ede1f7c046b 327 SUPERFAMILY SSF50249 6 137 2.4E-28 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CU254_RS10575 67ad868ad9581cb5163d4ede1f7c046b 327 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 230 295 4.3E-13 T 28-03-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal CU254_RS10575 67ad868ad9581cb5163d4ede1f7c046b 327 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 67 130 7.9E-13 T 28-03-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal CU254_RS10575 67ad868ad9581cb5163d4ede1f7c046b 327 SUPERFAMILY SSF50249 167 302 9.59E-38 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CU254_RS10575 67ad868ad9581cb5163d4ede1f7c046b 327 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 195 225 6.2E-9 T 28-03-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal CU254_RS26765 d935f5550088a2ea7b3d7f3ed1edd13d 199 Pfam PF01467 Cytidylyltransferase-like 8 168 6.9E-29 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CU254_RS26765 d935f5550088a2ea7b3d7f3ed1edd13d 199 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 6 70 6.5E-10 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CU254_RS26765 d935f5550088a2ea7b3d7f3ed1edd13d 199 Gene3D G3DSA:3.40.50.620 1 195 1.4E-52 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS26765 d935f5550088a2ea7b3d7f3ed1edd13d 199 SUPERFAMILY SSF52374 4 194 4.38E-53 T 28-03-2018 CU254_RS26765 d935f5550088a2ea7b3d7f3ed1edd13d 199 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 4 194 30.224 T 28-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 CU254_RS26765 d935f5550088a2ea7b3d7f3ed1edd13d 199 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 8 193 2.0E-54 T 28-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 CU254_RS37760 43c874381cad045a9013bbc1e2d7980a 292 SUPERFAMILY SSF50800 145 265 2.2E-18 T 28-03-2018 IPR011037 Pyruvate kinase-like, insert domain CU254_RS37760 43c874381cad045a9013bbc1e2d7980a 292 SUPERFAMILY SSF50800 2 44 2.2E-18 T 28-03-2018 IPR011037 Pyruvate kinase-like, insert domain CU254_RS37760 43c874381cad045a9013bbc1e2d7980a 292 SUPERFAMILY SSF141673 1 129 1.83E-28 T 28-03-2018 CU254_RS37760 43c874381cad045a9013bbc1e2d7980a 292 Pfam PF03476 MOSC N-terminal beta barrel domain 1 115 3.1E-27 T 28-03-2018 IPR005303 MOSC, N-terminal beta barrel CU254_RS37760 43c874381cad045a9013bbc1e2d7980a 292 Pfam PF03473 MOSC domain 137 262 1.8E-29 T 28-03-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 CU254_RS37760 43c874381cad045a9013bbc1e2d7980a 292 Gene3D G3DSA:2.40.33.20 1 277 5.4E-49 T 28-03-2018 CU254_RS00725 ee10f04e0fe401841eaf19ae90d1fc18 478 Gene3D G3DSA:1.20.5.320 438 478 5.5E-18 T 28-03-2018 CU254_RS00725 ee10f04e0fe401841eaf19ae90d1fc18 478 Gene3D G3DSA:1.10.1040.10 182 437 1.1E-99 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CU254_RS00725 ee10f04e0fe401841eaf19ae90d1fc18 478 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 180 469 6.1E-117 T 28-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CU254_RS00725 ee10f04e0fe401841eaf19ae90d1fc18 478 SUPERFAMILY SSF51735 5 177 5.26E-52 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS00725 ee10f04e0fe401841eaf19ae90d1fc18 478 Gene3D G3DSA:3.40.50.720 1 181 3.8E-41 T 28-03-2018 CU254_RS00725 ee10f04e0fe401841eaf19ae90d1fc18 478 TIGRFAM TIGR00873 gnd: 6-phosphogluconate dehydrogenase (decarboxylating) 7 470 1.2E-199 T 28-03-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CU254_RS00725 ee10f04e0fe401841eaf19ae90d1fc18 478 SMART SM01350 180 470 8.4E-193 T 28-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CU254_RS00725 ee10f04e0fe401841eaf19ae90d1fc18 478 PIRSF PIRSF000109 1 478 9.9E-194 T 28-03-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CU254_RS00725 ee10f04e0fe401841eaf19ae90d1fc18 478 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 6 175 5.5E-49 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CU254_RS00725 ee10f04e0fe401841eaf19ae90d1fc18 478 SUPERFAMILY SSF48179 178 473 3.8E-114 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CU254_RS00725 ee10f04e0fe401841eaf19ae90d1fc18 478 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 121 146 2.8E-79 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CU254_RS00725 ee10f04e0fe401841eaf19ae90d1fc18 478 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 5 28 2.8E-79 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CU254_RS00725 ee10f04e0fe401841eaf19ae90d1fc18 478 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 68 97 2.8E-79 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CU254_RS00725 ee10f04e0fe401841eaf19ae90d1fc18 478 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 169 197 2.8E-79 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CU254_RS00725 ee10f04e0fe401841eaf19ae90d1fc18 478 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 359 381 2.8E-79 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CU254_RS00725 ee10f04e0fe401841eaf19ae90d1fc18 478 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 251 278 2.8E-79 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CU254_RS00725 ee10f04e0fe401841eaf19ae90d1fc18 478 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 255 267 - T 28-03-2018 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CU254_RS11005 c51719e3c2b8f0eb072ec39a5be28199 374 Gene3D G3DSA:1.10.287.130 144 217 2.6E-15 T 28-03-2018 CU254_RS11005 c51719e3c2b8f0eb072ec39a5be28199 374 Pfam PF00512 His Kinase A (phospho-acceptor) domain 154 220 9.8E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS11005 c51719e3c2b8f0eb072ec39a5be28199 374 SUPERFAMILY SSF158472 101 151 1.57E-8 T 28-03-2018 CU254_RS11005 c51719e3c2b8f0eb072ec39a5be28199 374 SMART SM00388 154 221 2.5E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS11005 c51719e3c2b8f0eb072ec39a5be28199 374 Gene3D G3DSA:3.30.565.10 226 374 2.2E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS11005 c51719e3c2b8f0eb072ec39a5be28199 374 SMART SM00304 100 153 4.1E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS11005 c51719e3c2b8f0eb072ec39a5be28199 374 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 264 372 3.3E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS11005 c51719e3c2b8f0eb072ec39a5be28199 374 SMART SM00387 264 374 2.3E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS11005 c51719e3c2b8f0eb072ec39a5be28199 374 SUPERFAMILY SSF47384 137 219 1.1E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS11005 c51719e3c2b8f0eb072ec39a5be28199 374 PRINTS PR00344 Bacterial sensor protein C-terminal signature 212 226 1.1E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS11005 c51719e3c2b8f0eb072ec39a5be28199 374 PRINTS PR00344 Bacterial sensor protein C-terminal signature 319 329 1.1E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS11005 c51719e3c2b8f0eb072ec39a5be28199 374 PRINTS PR00344 Bacterial sensor protein C-terminal signature 335 353 1.1E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS11005 c51719e3c2b8f0eb072ec39a5be28199 374 PRINTS PR00344 Bacterial sensor protein C-terminal signature 359 372 1.1E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS11005 c51719e3c2b8f0eb072ec39a5be28199 374 SUPERFAMILY SSF55874 229 372 5.5E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS11005 c51719e3c2b8f0eb072ec39a5be28199 374 Pfam PF00672 HAMP domain 101 150 1.4E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS07065 acf3d6c79ec51347ea8eb0486601cdc5 328 Pfam PF00710 Asparaginase, N-terminal 3 190 1.5E-44 T 28-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 CU254_RS07065 acf3d6c79ec51347ea8eb0486601cdc5 328 SMART SM00870 3 317 9.0E-92 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CU254_RS07065 acf3d6c79ec51347ea8eb0486601cdc5 328 Gene3D G3DSA:3.40.50.1170 1 198 3.2E-41 T 28-03-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 CU254_RS07065 acf3d6c79ec51347ea8eb0486601cdc5 328 PRINTS PR00139 Asparaginase/glutaminase family signature 80 98 5.6E-10 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CU254_RS07065 acf3d6c79ec51347ea8eb0486601cdc5 328 PRINTS PR00139 Asparaginase/glutaminase family signature 4 15 5.6E-10 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CU254_RS07065 acf3d6c79ec51347ea8eb0486601cdc5 328 PRINTS PR00139 Asparaginase/glutaminase family signature 251 269 5.6E-10 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CU254_RS07065 acf3d6c79ec51347ea8eb0486601cdc5 328 PIRSF PIRSF001220 1 326 4.4E-68 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CU254_RS07065 acf3d6c79ec51347ea8eb0486601cdc5 328 SUPERFAMILY SSF53774 1 321 3.93E-74 T 28-03-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CU254_RS07065 acf3d6c79ec51347ea8eb0486601cdc5 328 Gene3D G3DSA:3.40.50.40 205 322 9.8E-19 T 28-03-2018 IPR027473 L-asparaginase, C-terminal domain Reactome: R-HSA-70614 CU254_RS07065 acf3d6c79ec51347ea8eb0486601cdc5 328 PIRSF PIRSF500176 1 324 4.8E-65 T 28-03-2018 CU254_RS39375 8c9bf72a455466d5c99ab3d59c0b6218 212 Gene3D G3DSA:2.30.110.10 12 212 7.5E-54 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS39375 8c9bf72a455466d5c99ab3d59c0b6218 212 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 172 212 5.0E-12 T 28-03-2018 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CU254_RS39375 8c9bf72a455466d5c99ab3d59c0b6218 212 SUPERFAMILY SSF50475 13 212 5.61E-48 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS39375 8c9bf72a455466d5c99ab3d59c0b6218 212 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 39 112 6.9E-19 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CU254_RS39375 8c9bf72a455466d5c99ab3d59c0b6218 212 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 20 212 2.4E-46 T 28-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CU254_RS39375 8c9bf72a455466d5c99ab3d59c0b6218 212 PIRSF PIRSF000190 8 212 5.8E-54 T 28-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CU254_RS33060 8760d89ad00b0ee172fd630c02a0d9c8 663 Pfam PF07993 Male sterility protein 6 232 7.3E-44 T 28-03-2018 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 CU254_RS33060 8760d89ad00b0ee172fd630c02a0d9c8 663 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 513 541 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS33060 8760d89ad00b0ee172fd630c02a0d9c8 663 Gene3D G3DSA:3.40.50.720 2 354 1.5E-43 T 28-03-2018 CU254_RS33060 8760d89ad00b0ee172fd630c02a0d9c8 663 Gene3D G3DSA:3.40.50.720 531 600 7.2E-12 T 28-03-2018 CU254_RS33060 8760d89ad00b0ee172fd630c02a0d9c8 663 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 500 516 1.2E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS33060 8760d89ad00b0ee172fd630c02a0d9c8 663 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 451 462 1.2E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS33060 8760d89ad00b0ee172fd630c02a0d9c8 663 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 377 394 1.2E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS33060 8760d89ad00b0ee172fd630c02a0d9c8 663 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 526 545 1.2E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS33060 8760d89ad00b0ee172fd630c02a0d9c8 663 SUPERFAMILY SSF51735 372 593 8.89E-62 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS33060 8760d89ad00b0ee172fd630c02a0d9c8 663 Gene3D G3DSA:3.40.50.720 372 530 3.6E-44 T 28-03-2018 CU254_RS33060 8760d89ad00b0ee172fd630c02a0d9c8 663 SUPERFAMILY SSF51735 305 362 3.44E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS33060 8760d89ad00b0ee172fd630c02a0d9c8 663 SUPERFAMILY SSF51735 1 273 3.44E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS33060 8760d89ad00b0ee172fd630c02a0d9c8 663 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 376 560 2.7E-5 T 28-03-2018 CU254_RS33060 8760d89ad00b0ee172fd630c02a0d9c8 663 Pfam PF00106 short chain dehydrogenase 377 565 1.7E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS33060 8760d89ad00b0ee172fd630c02a0d9c8 663 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 506 514 8.9E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS33060 8760d89ad00b0ee172fd630c02a0d9c8 663 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 526 545 8.9E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS33060 8760d89ad00b0ee172fd630c02a0d9c8 663 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 451 462 8.9E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS25485 6d76f80955959810a822f0d6410dd762 315 Gene3D G3DSA:3.40.50.880 1 193 8.3E-61 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS25485 6d76f80955959810a822f0d6410dd762 315 SMART SM00342 226 309 7.4E-25 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS25485 6d76f80955959810a822f0d6410dd762 315 Pfam PF01965 DJ-1/PfpI family 7 171 6.5E-28 T 28-03-2018 IPR002818 DJ-1/PfpI CU254_RS25485 6d76f80955959810a822f0d6410dd762 315 Gene3D G3DSA:1.10.10.60 194 266 4.0E-11 T 28-03-2018 CU254_RS25485 6d76f80955959810a822f0d6410dd762 315 Pfam PF12833 Helix-turn-helix domain 232 311 4.9E-22 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS25485 6d76f80955959810a822f0d6410dd762 315 SUPERFAMILY SSF46689 211 259 8.96E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS25485 6d76f80955959810a822f0d6410dd762 315 SUPERFAMILY SSF46689 262 312 2.33E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS25485 6d76f80955959810a822f0d6410dd762 315 SUPERFAMILY SSF52317 6 191 3.71E-52 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS25485 6d76f80955959810a822f0d6410dd762 315 Gene3D G3DSA:1.10.10.60 267 315 1.1E-11 T 28-03-2018 CU254_RS11725 23400659ecc0a95642773a5f38a06d7f 539 Gene3D G3DSA:3.40.50.10490 66 200 1.2E-29 T 28-03-2018 CU254_RS11725 23400659ecc0a95642773a5f38a06d7f 539 PRINTS PR00662 Glucose-6-phosphate isomerase signature 86 105 6.0E-8 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CU254_RS11725 23400659ecc0a95642773a5f38a06d7f 539 PRINTS PR00662 Glucose-6-phosphate isomerase signature 264 285 6.0E-8 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CU254_RS11725 23400659ecc0a95642773a5f38a06d7f 539 PRINTS PR00662 Glucose-6-phosphate isomerase signature 190 208 6.0E-8 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CU254_RS11725 23400659ecc0a95642773a5f38a06d7f 539 SUPERFAMILY SSF53697 27 374 1.21E-76 T 28-03-2018 CU254_RS11725 23400659ecc0a95642773a5f38a06d7f 539 Gene3D G3DSA:3.40.50.10490 201 303 5.1E-25 T 28-03-2018 CU254_RS11725 23400659ecc0a95642773a5f38a06d7f 539 Gene3D G3DSA:3.40.50.10490 328 385 2.7E-11 T 28-03-2018 CU254_RS11725 23400659ecc0a95642773a5f38a06d7f 539 Pfam PF00342 Phosphoglucose isomerase 83 286 1.7E-9 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CU254_RS03935 ab7ebf3c4f8e92b1a7a5aeadf0095818 392 Gene3D G3DSA:2.140.10.10 11 197 8.3E-9 T 28-03-2018 CU254_RS03935 ab7ebf3c4f8e92b1a7a5aeadf0095818 392 Gene3D G3DSA:2.140.10.10 218 389 0.043 T 28-03-2018 CU254_RS03935 ab7ebf3c4f8e92b1a7a5aeadf0095818 392 SUPERFAMILY SSF50998 36 132 7.26E-6 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CU254_RS03935 ab7ebf3c4f8e92b1a7a5aeadf0095818 392 SUPERFAMILY SSF50998 250 330 7.26E-6 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CU254_RS35735 741a8ffe1ae84b68ed8e27fa81dc4881 133 SMART SM00881 7 99 9.9E-26 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CU254_RS35735 741a8ffe1ae84b68ed8e27fa81dc4881 133 Pfam PF13380 CoA binding domain 11 124 1.1E-39 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CU254_RS35735 741a8ffe1ae84b68ed8e27fa81dc4881 133 Gene3D G3DSA:3.40.50.720 8 129 5.7E-34 T 28-03-2018 CU254_RS35735 741a8ffe1ae84b68ed8e27fa81dc4881 133 SUPERFAMILY SSF51735 4 126 1.86E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS05355 f3d9abb18dff0e0a1f4fcdcb6e99239f 176 Pfam PF13420 Acetyltransferase (GNAT) domain 6 159 3.6E-30 T 28-03-2018 CU254_RS05355 f3d9abb18dff0e0a1f4fcdcb6e99239f 176 SUPERFAMILY SSF55729 4 164 1.66E-31 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS05355 f3d9abb18dff0e0a1f4fcdcb6e99239f 176 Gene3D G3DSA:3.40.630.30 2 174 1.7E-32 T 28-03-2018 CU254_RS30740 4dc77dcdba857d71ca8692222691852f 199 Gene3D G3DSA:3.40.50.300 6 192 3.2E-17 T 28-03-2018 CU254_RS30740 4dc77dcdba857d71ca8692222691852f 199 Pfam PF03029 Conserved hypothetical ATP binding protein 21 188 4.0E-26 T 28-03-2018 IPR004130 GPN-loop GTPase CU254_RS30740 4dc77dcdba857d71ca8692222691852f 199 SUPERFAMILY SSF52540 17 186 1.37E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS32425 67b5d7adff64342f711c8d4e3379bcef 127 SUPERFAMILY SSF56784 22 121 1.8E-24 T 28-03-2018 IPR023214 HAD-like domain CU254_RS32425 67b5d7adff64342f711c8d4e3379bcef 127 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 28 106 4.7E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CU254_RS32425 67b5d7adff64342f711c8d4e3379bcef 127 Pfam PF13419 Haloacid dehalogenase-like hydrolase 25 107 4.3E-9 T 28-03-2018 IPR023214 HAD-like domain CU254_RS32425 67b5d7adff64342f711c8d4e3379bcef 127 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 24 111 2.2E-17 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CU254_RS32425 67b5d7adff64342f711c8d4e3379bcef 127 Gene3D G3DSA:3.40.50.1000 15 127 2.9E-22 T 28-03-2018 IPR023214 HAD-like domain CU254_RS11470 3bc7dd32d6bee9c613d1a6d5f5072f2a 310 SUPERFAMILY SSF53671 2 304 1.96E-91 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CU254_RS11470 3bc7dd32d6bee9c613d1a6d5f5072f2a 310 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 156 301 4.6E-22 T 28-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 CU254_RS11470 3bc7dd32d6bee9c613d1a6d5f5072f2a 310 PRINTS PR00101 Aspartate carbamoyltransferase signature 219 228 7.4E-32 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CU254_RS11470 3bc7dd32d6bee9c613d1a6d5f5072f2a 310 PRINTS PR00101 Aspartate carbamoyltransferase signature 135 152 7.4E-32 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CU254_RS11470 3bc7dd32d6bee9c613d1a6d5f5072f2a 310 PRINTS PR00101 Aspartate carbamoyltransferase signature 39 61 7.4E-32 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CU254_RS11470 3bc7dd32d6bee9c613d1a6d5f5072f2a 310 PRINTS PR00101 Aspartate carbamoyltransferase signature 260 265 7.4E-32 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CU254_RS11470 3bc7dd32d6bee9c613d1a6d5f5072f2a 310 PRINTS PR00101 Aspartate carbamoyltransferase signature 284 298 7.4E-32 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CU254_RS11470 3bc7dd32d6bee9c613d1a6d5f5072f2a 310 PRINTS PR00101 Aspartate carbamoyltransferase signature 77 86 7.4E-32 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CU254_RS11470 3bc7dd32d6bee9c613d1a6d5f5072f2a 310 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 2 149 2.6E-38 T 28-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 CU254_RS11470 3bc7dd32d6bee9c613d1a6d5f5072f2a 310 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 256 265 1.2E-18 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CU254_RS11470 3bc7dd32d6bee9c613d1a6d5f5072f2a 310 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 268 291 1.2E-18 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CU254_RS11470 3bc7dd32d6bee9c613d1a6d5f5072f2a 310 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 136 147 1.2E-18 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CU254_RS11470 3bc7dd32d6bee9c613d1a6d5f5072f2a 310 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 49 68 1.2E-18 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CU254_RS11470 3bc7dd32d6bee9c613d1a6d5f5072f2a 310 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 2 303 4.3E-85 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CU254_RS11470 3bc7dd32d6bee9c613d1a6d5f5072f2a 310 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 49 56 - T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CU254_RS11470 3bc7dd32d6bee9c613d1a6d5f5072f2a 310 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 1 305 38.671 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CU254_RS11470 3bc7dd32d6bee9c613d1a6d5f5072f2a 310 Gene3D G3DSA:3.40.50.1370 163 305 2.4E-44 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CU254_RS11470 3bc7dd32d6bee9c613d1a6d5f5072f2a 310 Gene3D G3DSA:3.40.50.1370 1 162 3.5E-59 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CU254_RS14535 8e64c30d49a2fe15b98b0d6a6822bad5 438 Pfam PF07690 Major Facilitator Superfamily 290 425 3.0E-8 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS14535 8e64c30d49a2fe15b98b0d6a6822bad5 438 Pfam PF00083 Sugar (and other) transporter 21 221 1.3E-21 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CU254_RS14535 8e64c30d49a2fe15b98b0d6a6822bad5 438 Gene3D G3DSA:1.20.1250.20 237 430 9.4E-20 T 28-03-2018 CU254_RS14535 8e64c30d49a2fe15b98b0d6a6822bad5 438 Gene3D G3DSA:1.20.1250.20 19 230 1.4E-25 T 28-03-2018 CU254_RS14535 8e64c30d49a2fe15b98b0d6a6822bad5 438 SUPERFAMILY SSF103473 21 425 5.75E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS18970 64b4b952de4457bee1ff80419cba698f 390 SUPERFAMILY SSF103473 11 380 8.24E-46 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS18970 64b4b952de4457bee1ff80419cba698f 390 Gene3D G3DSA:1.20.1250.20 5 191 1.4E-21 T 28-03-2018 CU254_RS18970 64b4b952de4457bee1ff80419cba698f 390 Gene3D G3DSA:1.20.1250.20 192 389 4.9E-11 T 28-03-2018 CU254_RS18970 64b4b952de4457bee1ff80419cba698f 390 Pfam PF07690 Major Facilitator Superfamily 12 307 8.2E-28 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS14875 59e2c3fa161308f983cf4c9ce2aeeb97 178 Gene3D G3DSA:1.10.260.40 2 157 2.3E-4 T 28-03-2018 CU254_RS14875 59e2c3fa161308f983cf4c9ce2aeeb97 178 SUPERFAMILY SSF47413 15 68 7.39E-6 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS35970 91b24fc0a91e0f1f8972c835f4f0e69b 163 Pfam PF02559 CarD-like/TRCF domain 3 111 1.3E-18 T 28-03-2018 IPR003711 CarD-like/TRCF domain CU254_RS35970 91b24fc0a91e0f1f8972c835f4f0e69b 163 SUPERFAMILY SSF141259 3 66 3.4E-14 T 28-03-2018 IPR003711 CarD-like/TRCF domain CU254_RS35970 91b24fc0a91e0f1f8972c835f4f0e69b 163 SMART SM01058 2 112 2.0E-33 T 28-03-2018 IPR003711 CarD-like/TRCF domain CU254_RS23240 7629de980d464ea861ff47ef2934414d 1087 ProSitePatterns PS00622 LuxR-type HTH domain signature. 1048 1075 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS23240 7629de980d464ea861ff47ef2934414d 1087 Gene3D G3DSA:3.40.50.300 193 406 7.7E-7 T 28-03-2018 CU254_RS23240 7629de980d464ea861ff47ef2934414d 1087 SMART SM00421 1031 1087 1.6E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS23240 7629de980d464ea861ff47ef2934414d 1087 Gene3D G3DSA:1.25.40.10 418 841 7.7E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS23240 7629de980d464ea861ff47ef2934414d 1087 SUPERFAMILY SSF46894 1023 1085 4.42E-16 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS23240 7629de980d464ea861ff47ef2934414d 1087 Pfam PF13191 AAA ATPase domain 197 322 2.4E-9 T 28-03-2018 CU254_RS23240 7629de980d464ea861ff47ef2934414d 1087 Pfam PF00196 Bacterial regulatory proteins, luxR family 1034 1084 4.9E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS23240 7629de980d464ea861ff47ef2934414d 1087 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 1064 1076 1.1E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS23240 7629de980d464ea861ff47ef2934414d 1087 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 1048 1064 1.1E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS23240 7629de980d464ea861ff47ef2934414d 1087 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 1034 1048 1.1E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS23240 7629de980d464ea861ff47ef2934414d 1087 SUPERFAMILY SSF52540 197 396 6.35E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS23240 7629de980d464ea861ff47ef2934414d 1087 Gene3D G3DSA:1.10.10.10 1008 1087 7.1E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS20215 1606ef0ec0db78c19572e897b14e8fc3 209 Gene3D G3DSA:1.10.10.60 14 76 3.3E-13 T 28-03-2018 CU254_RS20215 1606ef0ec0db78c19572e897b14e8fc3 209 SUPERFAMILY SSF46689 17 92 3.59E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS20215 1606ef0ec0db78c19572e897b14e8fc3 209 SUPERFAMILY SSF48498 99 203 2.27E-8 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS20215 1606ef0ec0db78c19572e897b14e8fc3 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 71 7.1E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS20215 1606ef0ec0db78c19572e897b14e8fc3 209 Gene3D G3DSA:1.10.357.10 77 209 6.7E-15 T 28-03-2018 CU254_RS05195 01e7d2c37f693d3c1961bb0b103f038b 684 SUPERFAMILY SSF49303 210 276 2.53E-9 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 CU254_RS05195 01e7d2c37f693d3c1961bb0b103f038b 684 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 278 460 3.4E-12 T 28-03-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 CU254_RS05195 01e7d2c37f693d3c1961bb0b103f038b 684 SUPERFAMILY SSF49785 17 181 3.54E-42 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS05195 01e7d2c37f693d3c1961bb0b103f038b 684 Gene3D G3DSA:2.60.40.10 179 272 1.8E-5 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS05195 01e7d2c37f693d3c1961bb0b103f038b 684 Pfam PF00703 Glycosyl hydrolases family 2 223 274 3.0E-5 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 CU254_RS05195 01e7d2c37f693d3c1961bb0b103f038b 684 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 62 178 9.1E-12 T 28-03-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CU254_RS05195 01e7d2c37f693d3c1961bb0b103f038b 684 Gene3D G3DSA:2.60.120.260 17 178 8.1E-39 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS05195 01e7d2c37f693d3c1961bb0b103f038b 684 Gene3D G3DSA:3.20.20.80 276 563 3.4E-43 T 28-03-2018 CU254_RS05195 01e7d2c37f693d3c1961bb0b103f038b 684 SUPERFAMILY SSF51445 484 555 1.11E-57 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS05195 01e7d2c37f693d3c1961bb0b103f038b 684 SUPERFAMILY SSF51445 273 452 1.11E-57 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS38205 5409737773ef61410c30b7a853239e64 120 Pfam PF03780 Asp23 family, cell envelope-related function 4 115 1.3E-13 T 28-03-2018 IPR005531 Alkaline shock protein Asp23 CU254_RS37450 744b6891dc6b74897648146b7bb191fe 299 Gene3D G3DSA:3.40.630.30 139 299 1.1E-28 T 28-03-2018 CU254_RS37450 744b6891dc6b74897648146b7bb191fe 299 SUPERFAMILY SSF55729 39 297 9.55E-46 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS37450 744b6891dc6b74897648146b7bb191fe 299 Hamap MF_01698 Mycothiol acetyltransferase [mshD]. 9 299 33.741 T 28-03-2018 IPR017813 Mycothiol acetyltransferase GO:0016747 CU254_RS37450 744b6891dc6b74897648146b7bb191fe 299 Pfam PF00583 Acetyltransferase (GNAT) family 185 288 3.9E-16 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS37450 744b6891dc6b74897648146b7bb191fe 299 Pfam PF00583 Acetyltransferase (GNAT) family 29 117 5.0E-10 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS37450 744b6891dc6b74897648146b7bb191fe 299 Gene3D G3DSA:3.40.630.30 6 138 7.8E-15 T 28-03-2018 CU254_RS37450 744b6891dc6b74897648146b7bb191fe 299 PIRSF PIRSF021524 4 299 2.1E-105 T 28-03-2018 IPR017813 Mycothiol acetyltransferase GO:0016747 CU254_RS37450 744b6891dc6b74897648146b7bb191fe 299 TIGRFAM TIGR03448 mycothiol_MshD: mycothiol synthase 10 297 1.5E-91 T 28-03-2018 IPR017813 Mycothiol acetyltransferase GO:0016747 CU254_RS15990 37b0f2b25d05e8aa465bc5537854afa5 472 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 297 315 1.3E-46 T 28-03-2018 CU254_RS15990 37b0f2b25d05e8aa465bc5537854afa5 472 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 315 331 1.3E-46 T 28-03-2018 CU254_RS15990 37b0f2b25d05e8aa465bc5537854afa5 472 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 141 156 1.3E-46 T 28-03-2018 CU254_RS15990 37b0f2b25d05e8aa465bc5537854afa5 472 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 279 295 1.3E-46 T 28-03-2018 CU254_RS15990 37b0f2b25d05e8aa465bc5537854afa5 472 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 264 279 1.3E-46 T 28-03-2018 CU254_RS15990 37b0f2b25d05e8aa465bc5537854afa5 472 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 1.3E-46 T 28-03-2018 CU254_RS15990 37b0f2b25d05e8aa465bc5537854afa5 472 Pfam PF01494 FAD binding domain 2 330 9.0E-85 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CU254_RS15990 37b0f2b25d05e8aa465bc5537854afa5 472 Gene3D G3DSA:3.50.50.60 2 374 1.8E-63 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS15990 37b0f2b25d05e8aa465bc5537854afa5 472 SUPERFAMILY SSF51905 2 162 3.17E-64 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS15990 37b0f2b25d05e8aa465bc5537854afa5 472 SUPERFAMILY SSF51905 251 341 3.17E-64 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS10405 73cc68402cf401477c4ac4423eaa176d 390 Gene3D G3DSA:3.40.47.10 12 126 1.2E-5 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS10405 73cc68402cf401477c4ac4423eaa176d 390 Gene3D G3DSA:3.40.47.10 147 385 9.3E-25 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS10405 73cc68402cf401477c4ac4423eaa176d 390 SUPERFAMILY SSF53901 264 378 1.02E-14 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS10405 73cc68402cf401477c4ac4423eaa176d 390 PIRSF PIRSF000429 1 388 9.4E-21 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CU254_RS10405 73cc68402cf401477c4ac4423eaa176d 390 Pfam PF00108 Thiolase, N-terminal domain 24 222 3.3E-8 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CU254_RS10405 73cc68402cf401477c4ac4423eaa176d 390 SUPERFAMILY SSF53901 4 233 2.39E-25 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS23085 dc82a8e5752a398dc15d7932f24fac5e 87 SUPERFAMILY SSF143744 21 72 2.09E-6 T 28-03-2018 CU254_RS35220 2deec25cec661b00cae613cfe56ac6bc 157 PRINTS PR00598 Bacterial regulatory protein MarR family signature 77 92 1.1E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS35220 2deec25cec661b00cae613cfe56ac6bc 157 PRINTS PR00598 Bacterial regulatory protein MarR family signature 60 76 1.1E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS35220 2deec25cec661b00cae613cfe56ac6bc 157 PRINTS PR00598 Bacterial regulatory protein MarR family signature 96 112 1.1E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS35220 2deec25cec661b00cae613cfe56ac6bc 157 PRINTS PR00598 Bacterial regulatory protein MarR family signature 126 146 1.1E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS35220 2deec25cec661b00cae613cfe56ac6bc 157 Gene3D G3DSA:1.10.10.10 2 156 2.5E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS35220 2deec25cec661b00cae613cfe56ac6bc 157 ProSitePatterns PS01117 MarR-type HTH domain signature. 75 109 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CU254_RS35220 2deec25cec661b00cae613cfe56ac6bc 157 SMART SM00347 35 136 5.6E-23 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS35220 2deec25cec661b00cae613cfe56ac6bc 157 Pfam PF01047 MarR family 42 101 1.7E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS35220 2deec25cec661b00cae613cfe56ac6bc 157 SUPERFAMILY SSF46785 23 151 4.01E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS28820 e4371294c2f7de6ef549239b21bec85e 329 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 325 2.7E-35 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS28820 e4371294c2f7de6ef549239b21bec85e 329 Gene3D G3DSA:1.10.3720.10 2 314 4.1E-33 T 28-03-2018 CU254_RS28820 e4371294c2f7de6ef549239b21bec85e 329 SUPERFAMILY SSF161098 189 308 1.83E-12 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS28820 e4371294c2f7de6ef549239b21bec85e 329 SUPERFAMILY SSF161098 96 162 1.83E-12 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS13925 e8c4d4ab563d8908a3a8686bb0232675 445 PRINTS PR00757 Flavin-containing amine oxidase signature 4 23 2.1E-5 T 28-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 CU254_RS13925 e8c4d4ab563d8908a3a8686bb0232675 445 PRINTS PR00757 Flavin-containing amine oxidase signature 415 432 2.1E-5 T 28-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 CU254_RS13925 e8c4d4ab563d8908a3a8686bb0232675 445 Pfam PF01593 Flavin containing amine oxidoreductase 12 434 3.9E-38 T 28-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 CU254_RS13925 e8c4d4ab563d8908a3a8686bb0232675 445 TIGRFAM TIGR03467 HpnE: squalene-associated FAD-dependent desaturase 5 435 4.2E-127 T 28-03-2018 IPR017830 Squalene-associated FAD-dependent desaturase CU254_RS13925 e8c4d4ab563d8908a3a8686bb0232675 445 Gene3D G3DSA:3.50.50.60 1 442 1.7E-36 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS13925 e8c4d4ab563d8908a3a8686bb0232675 445 SUPERFAMILY SSF51905 2 306 8.42E-54 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS13925 e8c4d4ab563d8908a3a8686bb0232675 445 SUPERFAMILY SSF51905 394 436 8.42E-54 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS16425 35a603e72afb10c7f3319d76803cf74c 204 Gene3D G3DSA:1.10.10.60 2 61 8.8E-18 T 28-03-2018 CU254_RS16425 35a603e72afb10c7f3319d76803cf74c 204 SUPERFAMILY SSF46689 8 80 2.98E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS16425 35a603e72afb10c7f3319d76803cf74c 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 4.3E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS16425 35a603e72afb10c7f3319d76803cf74c 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 4.3E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS16425 35a603e72afb10c7f3319d76803cf74c 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 61 1.7E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS16425 35a603e72afb10c7f3319d76803cf74c 204 Gene3D G3DSA:1.10.357.10 62 200 2.1E-20 T 28-03-2018 CU254_RS32470 242e1a90face29eb38b58a9d997dcbbe 745 Gene3D G3DSA:3.30.9.10 156 309 1.2E-20 T 28-03-2018 CU254_RS32470 242e1a90face29eb38b58a9d997dcbbe 745 Gene3D G3DSA:3.30.1360.120 393 520 9.7E-24 T 28-03-2018 CU254_RS32470 242e1a90face29eb38b58a9d997dcbbe 745 Gene3D G3DSA:3.30.1360.120 521 616 1.5E-12 T 28-03-2018 CU254_RS32470 242e1a90face29eb38b58a9d997dcbbe 745 Gene3D G3DSA:2.40.30.110 660 738 8.9E-23 T 28-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CU254_RS32470 242e1a90face29eb38b58a9d997dcbbe 745 SUPERFAMILY SSF101790 663 742 1.16E-19 T 28-03-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain CU254_RS32470 242e1a90face29eb38b58a9d997dcbbe 745 Pfam PF01571 Aminomethyltransferase folate-binding domain 398 640 5.1E-58 T 28-03-2018 IPR006222 Glycine cleavage T-protein-like, N-terminal CU254_RS32470 242e1a90face29eb38b58a9d997dcbbe 745 SUPERFAMILY SSF51905 310 372 1.21E-46 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS32470 242e1a90face29eb38b58a9d997dcbbe 745 SUPERFAMILY SSF51905 5 215 1.21E-46 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS32470 242e1a90face29eb38b58a9d997dcbbe 745 SUPERFAMILY SSF103025 392 655 4.4E-69 T 28-03-2018 CU254_RS32470 242e1a90face29eb38b58a9d997dcbbe 745 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 647 738 1.7E-19 T 28-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CU254_RS32470 242e1a90face29eb38b58a9d997dcbbe 745 Gene3D G3DSA:3.30.9.10 82 155 2.8E-7 T 28-03-2018 CU254_RS32470 242e1a90face29eb38b58a9d997dcbbe 745 Pfam PF01266 FAD dependent oxidoreductase 6 331 6.0E-34 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CU254_RS32470 242e1a90face29eb38b58a9d997dcbbe 745 Gene3D G3DSA:4.10.1250.10 618 658 5.6E-9 T 28-03-2018 CU254_RS32470 242e1a90face29eb38b58a9d997dcbbe 745 Gene3D G3DSA:3.50.50.60 1 73 1.2E-6 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS07155 1c6d2c4aad8e5f8a85b61e423602f668 63 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 63 16.116 T 28-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS07155 1c6d2c4aad8e5f8a85b61e423602f668 63 Pfam PF00830 Ribosomal L28 family 4 59 3.1E-20 T 28-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS07155 1c6d2c4aad8e5f8a85b61e423602f668 63 TIGRFAM TIGR00009 L28: ribosomal protein bL28 2 57 1.9E-19 T 28-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS07155 1c6d2c4aad8e5f8a85b61e423602f668 63 Gene3D G3DSA:2.30.170.40 2 63 4.2E-20 T 28-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS07155 1c6d2c4aad8e5f8a85b61e423602f668 63 SUPERFAMILY SSF143800 2 62 3.14E-21 T 28-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS18800 713478b56ade1f092c18d376e2e4853b 452 SUPERFAMILY SSF55874 300 445 2.62E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS18800 713478b56ade1f092c18d376e2e4853b 452 Gene3D G3DSA:3.30.565.10 307 452 3.8E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS18800 713478b56ade1f092c18d376e2e4853b 452 SMART SM00388 232 299 1.8E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS18800 713478b56ade1f092c18d376e2e4853b 452 Gene3D G3DSA:1.10.287.130 222 295 9.3E-16 T 28-03-2018 CU254_RS18800 713478b56ade1f092c18d376e2e4853b 452 SUPERFAMILY SSF158472 181 228 4.32E-7 T 28-03-2018 CU254_RS18800 713478b56ade1f092c18d376e2e4853b 452 Pfam PF00512 His Kinase A (phospho-acceptor) domain 232 298 1.0E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS18800 713478b56ade1f092c18d376e2e4853b 452 Pfam PF00672 HAMP domain 178 227 3.6E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS18800 713478b56ade1f092c18d376e2e4853b 452 SMART SM00387 339 445 2.9E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS18800 713478b56ade1f092c18d376e2e4853b 452 SUPERFAMILY SSF47384 215 298 4.32E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS18800 713478b56ade1f092c18d376e2e4853b 452 PRINTS PR00344 Bacterial sensor protein C-terminal signature 405 423 1.4E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS18800 713478b56ade1f092c18d376e2e4853b 452 PRINTS PR00344 Bacterial sensor protein C-terminal signature 372 386 1.4E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS18800 713478b56ade1f092c18d376e2e4853b 452 PRINTS PR00344 Bacterial sensor protein C-terminal signature 429 442 1.4E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS18800 713478b56ade1f092c18d376e2e4853b 452 PRINTS PR00344 Bacterial sensor protein C-terminal signature 390 400 1.4E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS18800 713478b56ade1f092c18d376e2e4853b 452 SMART SM00304 178 231 2.5E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS18800 713478b56ade1f092c18d376e2e4853b 452 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 340 443 6.6E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS18855 0b90cbe02d42aa913f5e12e009c9fa79 433 SUPERFAMILY SSF53720 19 420 8.93E-72 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CU254_RS18855 0b90cbe02d42aa913f5e12e009c9fa79 433 Pfam PF00815 Histidinol dehydrogenase 16 419 8.7E-141 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CU254_RS18855 0b90cbe02d42aa913f5e12e009c9fa79 433 Gene3D G3DSA:3.40.50.1980 218 363 4.8E-61 T 28-03-2018 CU254_RS18855 0b90cbe02d42aa913f5e12e009c9fa79 433 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 221 253 - T 28-03-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 CU254_RS18855 0b90cbe02d42aa913f5e12e009c9fa79 433 PRINTS PR00083 Histidinol dehydrogenase signature 221 242 1.8E-74 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CU254_RS18855 0b90cbe02d42aa913f5e12e009c9fa79 433 PRINTS PR00083 Histidinol dehydrogenase signature 25 49 1.8E-74 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CU254_RS18855 0b90cbe02d42aa913f5e12e009c9fa79 433 PRINTS PR00083 Histidinol dehydrogenase signature 353 371 1.8E-74 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CU254_RS18855 0b90cbe02d42aa913f5e12e009c9fa79 433 PRINTS PR00083 Histidinol dehydrogenase signature 162 188 1.8E-74 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CU254_RS18855 0b90cbe02d42aa913f5e12e009c9fa79 433 PRINTS PR00083 Histidinol dehydrogenase signature 192 217 1.8E-74 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CU254_RS18855 0b90cbe02d42aa913f5e12e009c9fa79 433 PRINTS PR00083 Histidinol dehydrogenase signature 243 262 1.8E-74 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CU254_RS18855 0b90cbe02d42aa913f5e12e009c9fa79 433 PRINTS PR00083 Histidinol dehydrogenase signature 312 337 1.8E-74 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CU254_RS18855 0b90cbe02d42aa913f5e12e009c9fa79 433 PRINTS PR00083 Histidinol dehydrogenase signature 100 127 1.8E-74 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CU254_RS18855 0b90cbe02d42aa913f5e12e009c9fa79 433 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 3 420 33.942 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CU254_RS18855 0b90cbe02d42aa913f5e12e009c9fa79 433 PIRSF PIRSF000099 3 423 1.4E-125 T 28-03-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CU254_RS18855 0b90cbe02d42aa913f5e12e009c9fa79 433 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 25 419 6.5E-138 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CU254_RS18855 0b90cbe02d42aa913f5e12e009c9fa79 433 Gene3D G3DSA:3.40.50.1980 18 217 3.9E-75 T 28-03-2018 CU254_RS23440 89f4e6f1357532d59f96def4caa4a61f 344 SUPERFAMILY SSF52343 104 229 1.83E-28 T 28-03-2018 CU254_RS23440 89f4e6f1357532d59f96def4caa4a61f 344 Pfam PF00970 Oxidoreductase FAD-binding domain 19 113 6.7E-11 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CU254_RS23440 89f4e6f1357532d59f96def4caa4a61f 344 Pfam PF00175 Oxidoreductase NAD-binding domain 124 220 1.7E-13 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CU254_RS23440 89f4e6f1357532d59f96def4caa4a61f 344 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 147 156 8.8E-9 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CU254_RS23440 89f4e6f1357532d59f96def4caa4a61f 344 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 207 215 8.8E-9 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CU254_RS23440 89f4e6f1357532d59f96def4caa4a61f 344 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 64 71 8.8E-9 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CU254_RS23440 89f4e6f1357532d59f96def4caa4a61f 344 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 123 142 8.8E-9 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CU254_RS23440 89f4e6f1357532d59f96def4caa4a61f 344 SUPERFAMILY SSF54292 231 339 1.84E-26 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CU254_RS23440 89f4e6f1357532d59f96def4caa4a61f 344 Gene3D G3DSA:3.10.20.30 231 344 2.7E-28 T 28-03-2018 IPR012675 Beta-grasp domain CU254_RS23440 89f4e6f1357532d59f96def4caa4a61f 344 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 263 335 6.3E-16 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CU254_RS23440 89f4e6f1357532d59f96def4caa4a61f 344 PRINTS PR00410 Phenol hydroxylase reductase family signature 123 142 4.4E-11 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CU254_RS23440 89f4e6f1357532d59f96def4caa4a61f 344 PRINTS PR00410 Phenol hydroxylase reductase family signature 45 57 4.4E-11 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CU254_RS23440 89f4e6f1357532d59f96def4caa4a61f 344 PRINTS PR00410 Phenol hydroxylase reductase family signature 207 215 4.4E-11 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CU254_RS23440 89f4e6f1357532d59f96def4caa4a61f 344 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 293 301 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CU254_RS23440 89f4e6f1357532d59f96def4caa4a61f 344 Gene3D G3DSA:3.40.50.80 105 230 5.2E-23 T 28-03-2018 CU254_RS23440 89f4e6f1357532d59f96def4caa4a61f 344 SUPERFAMILY SSF63380 17 113 4.8E-24 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CU254_RS23440 89f4e6f1357532d59f96def4caa4a61f 344 Gene3D G3DSA:2.40.30.10 3 104 6.2E-23 T 28-03-2018 CU254_RS38080 8559903cf6fba91008c2e578a34821f1 464 Gene3D G3DSA:3.20.20.150 235 419 0.0012 T 28-03-2018 CU254_RS38080 8559903cf6fba91008c2e578a34821f1 464 Gene3D G3DSA:3.30.465.10 95 234 7.1E-44 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CU254_RS38080 8559903cf6fba91008c2e578a34821f1 464 Gene3D G3DSA:1.10.45.10 420 459 1.4E-15 T 28-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CU254_RS38080 8559903cf6fba91008c2e578a34821f1 464 Pfam PF02913 FAD linked oxidases, C-terminal domain 218 458 7.3E-60 T 28-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CU254_RS38080 8559903cf6fba91008c2e578a34821f1 464 SUPERFAMILY SSF56176 4 218 2.43E-74 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CU254_RS38080 8559903cf6fba91008c2e578a34821f1 464 SUPERFAMILY SSF55103 222 460 1.96E-57 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CU254_RS38080 8559903cf6fba91008c2e578a34821f1 464 Pfam PF01565 FAD binding domain 42 180 6.6E-42 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CU254_RS38080 8559903cf6fba91008c2e578a34821f1 464 Gene3D G3DSA:3.30.43.10 1 94 1.0E-23 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CU254_RS05045 9e2c07169d06be456f6cb11fa8bf51c1 683 Gene3D G3DSA:3.40.50.670 440 678 9.0E-78 T 28-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CU254_RS05045 9e2c07169d06be456f6cb11fa8bf51c1 683 SUPERFAMILY SSF55874 7 226 2.73E-52 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS05045 9e2c07169d06be456f6cb11fa8bf51c1 683 Pfam PF00204 DNA gyrase B 241 431 2.3E-46 T 28-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CU254_RS05045 9e2c07169d06be456f6cb11fa8bf51c1 683 Gene3D G3DSA:3.30.565.10 19 239 3.7E-60 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS05045 9e2c07169d06be456f6cb11fa8bf51c1 683 PRINTS PR00418 DNA topoisomerase II family signature 306 319 3.0E-58 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CU254_RS05045 9e2c07169d06be456f6cb11fa8bf51c1 683 PRINTS PR00418 DNA topoisomerase II family signature 461 475 3.0E-58 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CU254_RS05045 9e2c07169d06be456f6cb11fa8bf51c1 683 PRINTS PR00418 DNA topoisomerase II family signature 36 51 3.0E-58 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CU254_RS05045 9e2c07169d06be456f6cb11fa8bf51c1 683 PRINTS PR00418 DNA topoisomerase II family signature 545 562 3.0E-58 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CU254_RS05045 9e2c07169d06be456f6cb11fa8bf51c1 683 PRINTS PR00418 DNA topoisomerase II family signature 613 629 3.0E-58 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CU254_RS05045 9e2c07169d06be456f6cb11fa8bf51c1 683 PRINTS PR00418 DNA topoisomerase II family signature 71 84 3.0E-58 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CU254_RS05045 9e2c07169d06be456f6cb11fa8bf51c1 683 PRINTS PR00418 DNA topoisomerase II family signature 565 577 3.0E-58 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CU254_RS05045 9e2c07169d06be456f6cb11fa8bf51c1 683 PRINTS PR00418 DNA topoisomerase II family signature 114 128 3.0E-58 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CU254_RS05045 9e2c07169d06be456f6cb11fa8bf51c1 683 PRINTS PR00418 DNA topoisomerase II family signature 527 543 3.0E-58 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CU254_RS05045 9e2c07169d06be456f6cb11fa8bf51c1 683 Gene3D G3DSA:3.30.230.10 240 435 2.5E-42 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CU254_RS05045 9e2c07169d06be456f6cb11fa8bf51c1 683 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 613 669 1.0E-22 T 28-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 CU254_RS05045 9e2c07169d06be456f6cb11fa8bf51c1 683 SMART SM00387 32 193 2.0E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS05045 9e2c07169d06be456f6cb11fa8bf51c1 683 Pfam PF01751 Toprim domain 460 560 1.7E-12 T 28-03-2018 IPR006171 TOPRIM domain CU254_RS05045 9e2c07169d06be456f6cb11fa8bf51c1 683 SUPERFAMILY SSF56719 435 676 4.71E-75 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CU254_RS05045 9e2c07169d06be456f6cb11fa8bf51c1 683 SMART SM00433 36 674 4.3E-212 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CU254_RS05045 9e2c07169d06be456f6cb11fa8bf51c1 683 ProSitePatterns PS00177 DNA topoisomerase II signature. 463 471 - T 28-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CU254_RS05045 9e2c07169d06be456f6cb11fa8bf51c1 683 PRINTS PR01159 DNA gyrase subunit B signature 199 214 9.7E-29 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CU254_RS05045 9e2c07169d06be456f6cb11fa8bf51c1 683 PRINTS PR01159 DNA gyrase subunit B signature 280 298 9.7E-29 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CU254_RS05045 9e2c07169d06be456f6cb11fa8bf51c1 683 PRINTS PR01159 DNA gyrase subunit B signature 415 435 9.7E-29 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CU254_RS05045 9e2c07169d06be456f6cb11fa8bf51c1 683 PRINTS PR01159 DNA gyrase subunit B signature 650 666 9.7E-29 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CU254_RS05045 9e2c07169d06be456f6cb11fa8bf51c1 683 PRINTS PR01159 DNA gyrase subunit B signature 351 367 9.7E-29 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CU254_RS05045 9e2c07169d06be456f6cb11fa8bf51c1 683 PRINTS PR01159 DNA gyrase subunit B signature 634 646 9.7E-29 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CU254_RS05045 9e2c07169d06be456f6cb11fa8bf51c1 683 PRINTS PR01159 DNA gyrase subunit B signature 7 17 9.7E-29 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CU254_RS05045 9e2c07169d06be456f6cb11fa8bf51c1 683 PRINTS PR01159 DNA gyrase subunit B signature 511 520 9.7E-29 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CU254_RS05045 9e2c07169d06be456f6cb11fa8bf51c1 683 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 32 136 4.5E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS05045 9e2c07169d06be456f6cb11fa8bf51c1 683 SUPERFAMILY SSF54211 287 431 1.19E-31 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CU254_RS21945 7a53e04db696fbb4cafeaf7ec137fd88 163 SUPERFAMILY SSF46785 12 147 1.17E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS21945 7a53e04db696fbb4cafeaf7ec137fd88 163 Pfam PF12802 MarR family 34 96 1.4E-15 T 28-03-2018 CU254_RS21945 7a53e04db696fbb4cafeaf7ec137fd88 163 Gene3D G3DSA:1.10.10.10 3 151 3.7E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS21945 7a53e04db696fbb4cafeaf7ec137fd88 163 SMART SM00347 29 132 8.9E-21 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS21945 7a53e04db696fbb4cafeaf7ec137fd88 163 ProSitePatterns PS00519 AsnC-type HTH domain signature. 57 83 - T 28-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site CU254_RS21945 7a53e04db696fbb4cafeaf7ec137fd88 163 PRINTS PR00598 Bacterial regulatory protein MarR family signature 73 88 2.2E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS21945 7a53e04db696fbb4cafeaf7ec137fd88 163 PRINTS PR00598 Bacterial regulatory protein MarR family signature 123 143 2.2E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS21945 7a53e04db696fbb4cafeaf7ec137fd88 163 PRINTS PR00598 Bacterial regulatory protein MarR family signature 92 108 2.2E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS21945 7a53e04db696fbb4cafeaf7ec137fd88 163 PRINTS PR00598 Bacterial regulatory protein MarR family signature 56 72 2.2E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS41035 6b84c0d8462c716dd2d49bac8f57f7dc 393 Gene3D G3DSA:3.40.50.300 164 387 1.0E-14 T 28-03-2018 CU254_RS41035 6b84c0d8462c716dd2d49bac8f57f7dc 393 SUPERFAMILY SSF53795 168 228 7.78E-8 T 28-03-2018 CU254_RS33610 7b49097057990006c00cbe103bb54985 283 Pfam PF03239 Iron permease FTR1 family 3 254 1.6E-55 T 28-03-2018 IPR004923 Iron permease FTR1/Fip1/EfeU GO:0005381|GO:0006827|GO:0016020|GO:0033573 CU254_RS04415 23c3221c90d966683bd3dd294bd7bfcb 312 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 42 270 5.2E-56 T 28-03-2018 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related CU254_RS27170 0884bdf4c12199547e934d22a61bea01 240 Pfam PF01738 Dienelactone hydrolase family 20 236 7.2E-28 T 28-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 CU254_RS27170 0884bdf4c12199547e934d22a61bea01 240 Gene3D G3DSA:3.40.50.1820 1 237 1.2E-31 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS27170 0884bdf4c12199547e934d22a61bea01 240 SUPERFAMILY SSF53474 5 240 5.86E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS34680 e56bd4efe6d502ccf9ad0cab4aad582a 215 Gene3D G3DSA:1.10.10.60 1 47 9.0E-16 T 28-03-2018 CU254_RS34680 e56bd4efe6d502ccf9ad0cab4aad582a 215 Gene3D G3DSA:1.10.357.10 48 190 6.4E-22 T 28-03-2018 CU254_RS34680 e56bd4efe6d502ccf9ad0cab4aad582a 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 53 3.9E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS34680 e56bd4efe6d502ccf9ad0cab4aad582a 215 SUPERFAMILY SSF48498 74 186 1.09E-16 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS34680 e56bd4efe6d502ccf9ad0cab4aad582a 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 7 20 1.8E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS34680 e56bd4efe6d502ccf9ad0cab4aad582a 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 51 1.8E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS34680 e56bd4efe6d502ccf9ad0cab4aad582a 215 SUPERFAMILY SSF46689 5 76 4.87E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS29500 ed493d346e6ce7ea90d7a61159dd3715 245 Pfam PF01614 Bacterial transcriptional regulator 124 239 1.3E-17 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal CU254_RS29500 ed493d346e6ce7ea90d7a61159dd3715 245 SMART SM00346 8 95 1.1E-9 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS29500 ed493d346e6ce7ea90d7a61159dd3715 245 Pfam PF09339 IclR helix-turn-helix domain 10 57 4.5E-13 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS29500 ed493d346e6ce7ea90d7a61159dd3715 245 Gene3D G3DSA:1.10.10.10 1 67 8.3E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS29500 ed493d346e6ce7ea90d7a61159dd3715 245 SUPERFAMILY SSF46785 8 74 4.19E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS29500 ed493d346e6ce7ea90d7a61159dd3715 245 Gene3D G3DSA:3.30.450.40 79 245 5.8E-29 T 28-03-2018 IPR029016 GAF domain-like CU254_RS29500 ed493d346e6ce7ea90d7a61159dd3715 245 SUPERFAMILY SSF55781 64 241 8.5E-28 T 28-03-2018 IPR029016 GAF domain-like CU254_RS26855 5a2a312478ccd1e92e77e79d7a963d7f 279 PRINTS PR00164 ABC-2 type transport system membrane protein signature 165 189 1.1E-17 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CU254_RS26855 5a2a312478ccd1e92e77e79d7a963d7f 279 PRINTS PR00164 ABC-2 type transport system membrane protein signature 128 153 1.1E-17 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CU254_RS26855 5a2a312478ccd1e92e77e79d7a963d7f 279 PRINTS PR00164 ABC-2 type transport system membrane protein signature 48 69 1.1E-17 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CU254_RS26855 5a2a312478ccd1e92e77e79d7a963d7f 279 PRINTS PR00164 ABC-2 type transport system membrane protein signature 221 240 1.1E-17 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CU254_RS26855 5a2a312478ccd1e92e77e79d7a963d7f 279 PRINTS PR00164 ABC-2 type transport system membrane protein signature 201 220 1.1E-17 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CU254_RS26855 5a2a312478ccd1e92e77e79d7a963d7f 279 PIRSF PIRSF006648 7 277 2.9E-30 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CU254_RS26855 5a2a312478ccd1e92e77e79d7a963d7f 279 Pfam PF01061 ABC-2 type transporter 32 241 7.3E-23 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CU254_RS07300 621a0923d8a8a6679aacb031d29bea4f 707 SUPERFAMILY SSF52540 315 399 2.61E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS07300 621a0923d8a8a6679aacb031d29bea4f 707 SUPERFAMILY SSF52540 183 261 2.61E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS07300 621a0923d8a8a6679aacb031d29bea4f 707 SUPERFAMILY SSF52540 486 702 2.61E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS07300 621a0923d8a8a6679aacb031d29bea4f 707 Pfam PF13245 AAA domain 196 530 3.3E-9 T 28-03-2018 CU254_RS07300 621a0923d8a8a6679aacb031d29bea4f 707 Gene3D G3DSA:3.40.50.300 188 543 1.4E-28 T 28-03-2018 CU254_RS07300 621a0923d8a8a6679aacb031d29bea4f 707 Pfam PF13538 UvrD-like helicase C-terminal domain 656 696 4.2E-9 T 28-03-2018 IPR027785 UvrD-like helicase C-terminal domain CU254_RS07300 621a0923d8a8a6679aacb031d29bea4f 707 Gene3D G3DSA:3.40.50.300 557 705 5.8E-15 T 28-03-2018 CU254_RS21655 53938174985bc9779b0a106fee3cfc34 517 Pfam PF13727 CoA-binding domain 160 259 5.5E-6 T 28-03-2018 CU254_RS21655 53938174985bc9779b0a106fee3cfc34 517 Gene3D G3DSA:3.40.50.720 193 311 8.9E-12 T 28-03-2018 CU254_RS21655 53938174985bc9779b0a106fee3cfc34 517 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 79 517 2.9E-120 T 28-03-2018 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase CU254_RS21655 53938174985bc9779b0a106fee3cfc34 517 Pfam PF02397 Bacterial sugar transferase 324 511 1.1E-64 T 28-03-2018 IPR003362 Bacterial sugar transferase CU254_RS26145 22821ffca4e95c7a000f6b1b829553ae 437 Gene3D G3DSA:1.20.1250.20 24 223 1.4E-16 T 28-03-2018 CU254_RS26145 22821ffca4e95c7a000f6b1b829553ae 437 Gene3D G3DSA:1.20.1250.20 233 430 1.3E-11 T 28-03-2018 CU254_RS26145 22821ffca4e95c7a000f6b1b829553ae 437 Pfam PF07690 Major Facilitator Superfamily 35 247 1.3E-11 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS26145 22821ffca4e95c7a000f6b1b829553ae 437 SUPERFAMILY SSF103473 32 422 3.75E-28 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS20780 652c44dadd5c2a90221d6f65f5a5180b 1535 SUPERFAMILY SSF63825 54 291 7.59E-10 T 28-03-2018 CU254_RS20780 652c44dadd5c2a90221d6f65f5a5180b 1535 Pfam PF01345 Domain of unknown function DUF11 1228 1325 2.9E-9 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CU254_RS20780 652c44dadd5c2a90221d6f65f5a5180b 1535 Pfam PF01345 Domain of unknown function DUF11 334 438 2.4E-9 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CU254_RS20780 652c44dadd5c2a90221d6f65f5a5180b 1535 Pfam PF01345 Domain of unknown function DUF11 592 698 1.6E-11 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CU254_RS20780 652c44dadd5c2a90221d6f65f5a5180b 1535 Pfam PF01345 Domain of unknown function DUF11 1354 1452 2.6E-7 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CU254_RS20780 652c44dadd5c2a90221d6f65f5a5180b 1535 Pfam PF01345 Domain of unknown function DUF11 979 1076 5.3E-9 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CU254_RS20780 652c44dadd5c2a90221d6f65f5a5180b 1535 Pfam PF01345 Domain of unknown function DUF11 852 949 6.1E-10 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CU254_RS20780 652c44dadd5c2a90221d6f65f5a5180b 1535 Pfam PF01345 Domain of unknown function DUF11 1104 1200 9.6E-8 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CU254_RS20780 652c44dadd5c2a90221d6f65f5a5180b 1535 Pfam PF01345 Domain of unknown function DUF11 466 565 2.8E-7 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CU254_RS20780 652c44dadd5c2a90221d6f65f5a5180b 1535 Pfam PF01345 Domain of unknown function DUF11 725 822 6.5E-10 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CU254_RS20780 652c44dadd5c2a90221d6f65f5a5180b 1535 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1357 1390 5.4E-4 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CU254_RS20780 652c44dadd5c2a90221d6f65f5a5180b 1535 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 336 374 5.7E-9 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CU254_RS20780 652c44dadd5c2a90221d6f65f5a5180b 1535 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 727 764 3.6E-7 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CU254_RS20780 652c44dadd5c2a90221d6f65f5a5180b 1535 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 594 628 7.2E-10 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CU254_RS20780 652c44dadd5c2a90221d6f65f5a5180b 1535 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1106 1142 6.3E-5 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CU254_RS20780 652c44dadd5c2a90221d6f65f5a5180b 1535 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1230 1267 2.6E-7 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CU254_RS20780 652c44dadd5c2a90221d6f65f5a5180b 1535 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 468 502 4.3E-6 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CU254_RS20780 652c44dadd5c2a90221d6f65f5a5180b 1535 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 854 891 1.3E-7 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CU254_RS20780 652c44dadd5c2a90221d6f65f5a5180b 1535 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 981 1015 2.7E-6 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CU254_RS20780 652c44dadd5c2a90221d6f65f5a5180b 1535 Gene3D G3DSA:2.60.40.1580 1348 1494 6.1E-28 T 28-03-2018 CU254_RS20780 652c44dadd5c2a90221d6f65f5a5180b 1535 Gene3D G3DSA:2.60.40.1580 464 588 5.3E-27 T 28-03-2018 CU254_RS20780 652c44dadd5c2a90221d6f65f5a5180b 1535 Gene3D G3DSA:2.60.40.1580 328 457 3.7E-32 T 28-03-2018 CU254_RS20780 652c44dadd5c2a90221d6f65f5a5180b 1535 Gene3D G3DSA:2.60.40.1580 976 1089 1.4E-31 T 28-03-2018 CU254_RS20780 652c44dadd5c2a90221d6f65f5a5180b 1535 Gene3D G3DSA:2.60.40.1580 1228 1338 2.4E-32 T 28-03-2018 CU254_RS20780 652c44dadd5c2a90221d6f65f5a5180b 1535 Gene3D G3DSA:2.60.40.1580 1103 1214 2.8E-30 T 28-03-2018 CU254_RS20780 652c44dadd5c2a90221d6f65f5a5180b 1535 Gene3D G3DSA:2.60.40.1580 589 723 1.8E-27 T 28-03-2018 CU254_RS20780 652c44dadd5c2a90221d6f65f5a5180b 1535 Gene3D G3DSA:2.60.40.1580 724 833 5.4E-34 T 28-03-2018 CU254_RS20780 652c44dadd5c2a90221d6f65f5a5180b 1535 Gene3D G3DSA:2.60.40.1580 852 963 1.0E-33 T 28-03-2018 CU254_RS39210 972a3f0c9a8a2e6267fbfc6f93f85f17 179 Pfam PF01424 R3H domain 118 177 3.3E-15 T 28-03-2018 IPR001374 R3H domain GO:0003676 CU254_RS39210 972a3f0c9a8a2e6267fbfc6f93f85f17 179 Gene3D G3DSA:3.30.300.20 30 108 4.1E-18 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CU254_RS39210 972a3f0c9a8a2e6267fbfc6f93f85f17 179 Gene3D G3DSA:3.30.1370.50 110 179 2.0E-19 T 28-03-2018 IPR001374 R3H domain GO:0003676 CU254_RS39210 972a3f0c9a8a2e6267fbfc6f93f85f17 179 SUPERFAMILY SSF82708 131 177 1.0E-10 T 28-03-2018 IPR001374 R3H domain GO:0003676 CU254_RS39210 972a3f0c9a8a2e6267fbfc6f93f85f17 179 SMART SM00393 99 178 4.9E-25 T 28-03-2018 IPR001374 R3H domain GO:0003676 CU254_RS26300 7a09bb1b4e3a3c1bfc827b81346c1650 637 Hamap MF_00974 DNA primase [dnaG]. 4 620 25.619 T 28-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 CU254_RS26300 7a09bb1b4e3a3c1bfc827b81346c1650 637 Gene3D G3DSA:1.10.860.10 471 619 3.9E-25 T 28-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal CU254_RS26300 7a09bb1b4e3a3c1bfc827b81346c1650 637 Gene3D G3DSA:3.90.980.10 110 243 4.9E-40 T 28-03-2018 IPR013264 DNA primase, catalytic core, N-terminal CU254_RS26300 7a09bb1b4e3a3c1bfc827b81346c1650 637 Pfam PF13662 Toprim domain 263 333 2.1E-15 T 28-03-2018 IPR006171 TOPRIM domain CU254_RS26300 7a09bb1b4e3a3c1bfc827b81346c1650 637 TIGRFAM TIGR01391 dnaG: DNA primase 5 423 3.9E-114 T 28-03-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 CU254_RS26300 7a09bb1b4e3a3c1bfc827b81346c1650 637 Pfam PF01807 CHC2 zinc finger 7 101 1.1E-33 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CU254_RS26300 7a09bb1b4e3a3c1bfc827b81346c1650 637 SMART SM00493 262 340 4.7E-15 T 28-03-2018 IPR006171 TOPRIM domain CU254_RS26300 7a09bb1b4e3a3c1bfc827b81346c1650 637 SUPERFAMILY SSF56731 117 432 3.66E-93 T 28-03-2018 CU254_RS26300 7a09bb1b4e3a3c1bfc827b81346c1650 637 Pfam PF10410 DnaB-helicase binding domain of primase 376 428 1.3E-13 T 28-03-2018 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 CU254_RS26300 7a09bb1b4e3a3c1bfc827b81346c1650 637 Pfam PF08275 DNA primase catalytic core, N-terminal domain 127 255 2.8E-35 T 28-03-2018 IPR013264 DNA primase, catalytic core, N-terminal CU254_RS26300 7a09bb1b4e3a3c1bfc827b81346c1650 637 SMART SM00400 37 91 2.9E-35 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CU254_RS26300 7a09bb1b4e3a3c1bfc827b81346c1650 637 SUPERFAMILY SSF57783 4 99 4.59E-32 T 28-03-2018 CU254_RS26300 7a09bb1b4e3a3c1bfc827b81346c1650 637 Pfam PF08278 DNA primase DnaG DnaB-binding 487 614 2.7E-23 T 28-03-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 CU254_RS26300 7a09bb1b4e3a3c1bfc827b81346c1650 637 Gene3D G3DSA:3.90.580.10 1 102 5.9E-33 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CU254_RS26300 7a09bb1b4e3a3c1bfc827b81346c1650 637 PIRSF PIRSF002811 2 626 1.4E-144 T 28-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 CU254_RS26300 7a09bb1b4e3a3c1bfc827b81346c1650 637 SMART SM00766 486 615 1.3E-18 T 28-03-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 CU254_RS26300 7a09bb1b4e3a3c1bfc827b81346c1650 637 Gene3D G3DSA:1.20.50.20 375 428 4.2E-16 T 28-03-2018 CU254_RS26300 7a09bb1b4e3a3c1bfc827b81346c1650 637 Gene3D G3DSA:3.40.1360.10 244 374 8.8E-30 T 28-03-2018 CU254_RS02205 692db754ab3ec6fe02ff1ad28a8f1402 162 ProSitePatterns PS00360 Ribosomal protein S9 signature. 101 119 - T 28-03-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 CU254_RS02205 692db754ab3ec6fe02ff1ad28a8f1402 162 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 33 162 32.739 T 28-03-2018 IPR023035 Ribosomal protein S9, bacterial/plastid CU254_RS02205 692db754ab3ec6fe02ff1ad28a8f1402 162 Gene3D G3DSA:3.30.230.10 36 162 1.6E-49 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CU254_RS02205 692db754ab3ec6fe02ff1ad28a8f1402 162 Pfam PF00380 Ribosomal protein S9/S16 42 162 8.7E-44 T 28-03-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 CU254_RS02205 692db754ab3ec6fe02ff1ad28a8f1402 162 SUPERFAMILY SSF54211 38 162 5.31E-45 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CU254_RS26835 ef8298ebcc54f8b24a1c0bc0df67d7b3 85 Gene3D G3DSA:2.40.50.100 20 83 2.0E-28 T 28-03-2018 CU254_RS26835 ef8298ebcc54f8b24a1c0bc0df67d7b3 85 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 69 1.0E-15 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS26835 ef8298ebcc54f8b24a1c0bc0df67d7b3 85 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 81 3.4E-36 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS26835 ef8298ebcc54f8b24a1c0bc0df67d7b3 85 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 83 27.769 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS26835 ef8298ebcc54f8b24a1c0bc0df67d7b3 85 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 28-03-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS26835 ef8298ebcc54f8b24a1c0bc0df67d7b3 85 PRINTS PR00063 Ribosomal protein L27 signature 29 53 2.1E-36 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS26835 ef8298ebcc54f8b24a1c0bc0df67d7b3 85 PRINTS PR00063 Ribosomal protein L27 signature 54 78 2.1E-36 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS26835 ef8298ebcc54f8b24a1c0bc0df67d7b3 85 PRINTS PR00063 Ribosomal protein L27 signature 4 28 2.1E-36 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS26835 ef8298ebcc54f8b24a1c0bc0df67d7b3 85 Pfam PF01016 Ribosomal L27 protein 2 80 3.5E-36 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS26835 ef8298ebcc54f8b24a1c0bc0df67d7b3 85 SUPERFAMILY SSF110324 2 81 3.28E-31 T 28-03-2018 CU254_RS40310 96bdb38c7b598d7c0243da9639f5729f 295 Pfam PF00296 Luciferase-like monooxygenase 21 236 9.3E-46 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS40310 96bdb38c7b598d7c0243da9639f5729f 295 Gene3D G3DSA:3.20.20.30 1 250 1.6E-55 T 28-03-2018 CU254_RS40310 96bdb38c7b598d7c0243da9639f5729f 295 Gene3D G3DSA:3.20.20.30 251 295 0.067 T 28-03-2018 CU254_RS40310 96bdb38c7b598d7c0243da9639f5729f 295 SUPERFAMILY SSF51679 20 293 3.93E-51 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS26210 252c6e8c5dab496e3946cf4052182509 184 Pfam PF12079 Protein of unknown function (DUF3558) 29 169 3.8E-15 T 28-03-2018 IPR024520 Protein of unknown function DUF3558 CU254_RS37275 7f4b565eba003931790829c12e125628 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 58 2.4E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS37275 7f4b565eba003931790829c12e125628 188 SUPERFAMILY SSF46689 3 67 1.4E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS37275 7f4b565eba003931790829c12e125628 188 SUPERFAMILY SSF48498 72 186 1.19E-22 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS37275 7f4b565eba003931790829c12e125628 188 Pfam PF16859 Bacterial transcriptional repressor C-terminal 71 182 1.2E-27 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS37275 7f4b565eba003931790829c12e125628 188 Gene3D G3DSA:1.10.357.10 64 188 2.3E-18 T 28-03-2018 CU254_RS37275 7f4b565eba003931790829c12e125628 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 1.3E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS37275 7f4b565eba003931790829c12e125628 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 1.3E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS37275 7f4b565eba003931790829c12e125628 188 Gene3D G3DSA:1.10.10.60 1 63 5.1E-17 T 28-03-2018 CU254_RS09605 61cf90da3124f4bf57098215878fa75f 308 SUPERFAMILY SSF47413 13 69 2.76E-9 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS09605 61cf90da3124f4bf57098215878fa75f 308 SMART SM00530 17 72 2.6E-6 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS09605 61cf90da3124f4bf57098215878fa75f 308 Gene3D G3DSA:1.10.260.40 3 80 3.7E-12 T 28-03-2018 CU254_RS09605 61cf90da3124f4bf57098215878fa75f 308 Pfam PF13560 Helix-turn-helix domain 14 70 8.6E-9 T 28-03-2018 CU254_RS07825 11562a71a60107d87a24988d1be50a07 448 SUPERFAMILY SSF103473 16 192 1.57E-5 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS07825 11562a71a60107d87a24988d1be50a07 448 TIGRFAM TIGR03173 pbuX: xanthine permease 26 431 2.1E-146 T 28-03-2018 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 CU254_RS07825 11562a71a60107d87a24988d1be50a07 448 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 16 430 9.7E-105 T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CU254_RS07825 11562a71a60107d87a24988d1be50a07 448 Pfam PF00860 Permease family 21 399 6.2E-91 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CU254_RS07825 11562a71a60107d87a24988d1be50a07 448 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 347 367 - T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CU254_RS36240 c14f896c54d2848df54cb3ff6c45a652 117 Gene3D G3DSA:3.20.20.140 5 114 6.5E-4 T 28-03-2018 CU254_RS36240 c14f896c54d2848df54cb3ff6c45a652 117 Pfam PF11774 Lsr2 1 115 2.2E-44 T 28-03-2018 IPR024412 Lsr2 CU254_RS36240 c14f896c54d2848df54cb3ff6c45a652 117 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 1 115 1.0E-31 T 28-03-2018 IPR024412 Lsr2 CU254_RS21735 681aac7db637042bd4c2c0c0bbb5d0a1 522 Gene3D G3DSA:2.30.38.10 328 412 9.4E-24 T 28-03-2018 CU254_RS21735 681aac7db637042bd4c2c0c0bbb5d0a1 522 Gene3D G3DSA:3.40.50.980 4 172 4.0E-42 T 28-03-2018 CU254_RS21735 681aac7db637042bd4c2c0c0bbb5d0a1 522 Gene3D G3DSA:3.40.50.980 173 327 4.2E-40 T 28-03-2018 CU254_RS21735 681aac7db637042bd4c2c0c0bbb5d0a1 522 Pfam PF13193 AMP-binding enzyme C-terminal domain 428 503 2.0E-21 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS21735 681aac7db637042bd4c2c0c0bbb5d0a1 522 SUPERFAMILY SSF56801 5 515 6.67E-147 T 28-03-2018 CU254_RS21735 681aac7db637042bd4c2c0c0bbb5d0a1 522 Pfam PF00501 AMP-binding enzyme 16 419 1.6E-95 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS21735 681aac7db637042bd4c2c0c0bbb5d0a1 522 Gene3D G3DSA:3.30.300.30 414 522 4.1E-32 T 28-03-2018 CU254_RS16830 9c2d491e0167b66247bfba21c0d40816 581 Gene3D G3DSA:3.40.50.300 329 579 1.0E-67 T 28-03-2018 CU254_RS16830 9c2d491e0167b66247bfba21c0d40816 581 Pfam PF00005 ABC transporter 351 501 2.0E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS16830 9c2d491e0167b66247bfba21c0d40816 581 Pfam PF00005 ABC transporter 21 171 3.9E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS16830 9c2d491e0167b66247bfba21c0d40816 581 SUPERFAMILY SSF52540 333 571 2.66E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS16830 9c2d491e0167b66247bfba21c0d40816 581 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS16830 9c2d491e0167b66247bfba21c0d40816 581 SUPERFAMILY SSF52540 6 252 2.51E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS16830 9c2d491e0167b66247bfba21c0d40816 581 ProSitePatterns PS00211 ABC transporters family signature. 473 487 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS16830 9c2d491e0167b66247bfba21c0d40816 581 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 221 305 4.5E-22 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CU254_RS16830 9c2d491e0167b66247bfba21c0d40816 581 Gene3D G3DSA:3.40.50.300 2 319 6.8E-76 T 28-03-2018 CU254_RS16830 9c2d491e0167b66247bfba21c0d40816 581 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 551 577 1.4E-4 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CU254_RS16830 9c2d491e0167b66247bfba21c0d40816 581 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 223 286 4.2E-19 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CU254_RS16830 9c2d491e0167b66247bfba21c0d40816 581 SMART SM00382 29 221 1.0E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS16830 9c2d491e0167b66247bfba21c0d40816 581 SMART SM00382 358 549 1.9E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS32635 f546660a67c9d04973a5a28fab2d9fa3 307 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 120 302 6.2E-30 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS32635 f546660a67c9d04973a5a28fab2d9fa3 307 SUPERFAMILY SSF161098 98 284 5.49E-27 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS32635 f546660a67c9d04973a5a28fab2d9fa3 307 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 28 79 2.6E-11 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CU254_RS32635 f546660a67c9d04973a5a28fab2d9fa3 307 Gene3D G3DSA:1.10.3720.10 23 292 2.0E-43 T 28-03-2018 CU254_RS29775 12270f782e127254711d257e47970053 373 Gene3D G3DSA:3.90.180.10 306 372 1.7E-4 T 28-03-2018 CU254_RS29775 12270f782e127254711d257e47970053 373 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 155 5.8E-28 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CU254_RS29775 12270f782e127254711d257e47970053 373 SUPERFAMILY SSF50129 321 369 1.32E-8 T 28-03-2018 IPR011032 GroES-like CU254_RS29775 12270f782e127254711d257e47970053 373 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 60 74 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CU254_RS29775 12270f782e127254711d257e47970053 373 Pfam PF00107 Zinc-binding dehydrogenase 197 324 1.5E-20 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CU254_RS29775 12270f782e127254711d257e47970053 373 SUPERFAMILY SSF50129 1 192 9.02E-57 T 28-03-2018 IPR011032 GroES-like CU254_RS29775 12270f782e127254711d257e47970053 373 SUPERFAMILY SSF51735 159 334 6.03E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS29775 12270f782e127254711d257e47970053 373 TIGRFAM TIGR03989 Rxyl_3153: NDMA-dependent alcohol dehydrogenase, Rxyl_3153 family 2 370 3.3E-157 T 28-03-2018 IPR023921 Alcohol dehydrogenase, zinc-type, actinomycetes KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396 CU254_RS29775 12270f782e127254711d257e47970053 373 SMART SM00829 12 368 3.9E-5 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CU254_RS29775 12270f782e127254711d257e47970053 373 Gene3D G3DSA:3.40.50.720 190 305 6.0E-18 T 28-03-2018 CU254_RS29775 12270f782e127254711d257e47970053 373 Gene3D G3DSA:3.90.180.10 1 189 2.6E-54 T 28-03-2018 CU254_RS21100 28c25e86f2c24b72c4b778017aaf04f5 357 Gene3D G3DSA:3.20.20.70 6 304 1.3E-41 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS21100 28c25e86f2c24b72c4b778017aaf04f5 357 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 236 329 1.5E-10 T 28-03-2018 IPR023885 4Fe4S-binding SPASM domain CU254_RS21100 28c25e86f2c24b72c4b778017aaf04f5 357 PIRSF PIRSF037420 1 346 9.2E-104 T 28-03-2018 CU254_RS21100 28c25e86f2c24b72c4b778017aaf04f5 357 Hamap MF_00660 Coenzyme PQQ synthesis protein E [pqqE]. 1 357 162.677 T 28-03-2018 IPR011843 Coenzyme PQQ biosynthesis protein E, bacteria GO:0018189|GO:0051539 CU254_RS21100 28c25e86f2c24b72c4b778017aaf04f5 357 TIGRFAM TIGR02109 PQQ_syn_pqqE: coenzyme PQQ biosynthesis enzyme PqqE 3 339 5.3E-161 T 28-03-2018 IPR011843 Coenzyme PQQ biosynthesis protein E, bacteria GO:0018189|GO:0051539 CU254_RS21100 28c25e86f2c24b72c4b778017aaf04f5 357 Pfam PF04055 Radical SAM superfamily 13 167 1.4E-20 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CU254_RS21100 28c25e86f2c24b72c4b778017aaf04f5 357 Pfam PF13186 Iron-sulfur cluster-binding domain 236 302 9.2E-11 T 28-03-2018 IPR023885 4Fe4S-binding SPASM domain CU254_RS21100 28c25e86f2c24b72c4b778017aaf04f5 357 SUPERFAMILY SSF102114 6 311 1.7E-66 T 28-03-2018 CU254_RS37880 0654111af78c89b46762a239e30b6ee3 252 Pfam PF14011 EspG family 6 247 7.7E-60 T 28-03-2018 IPR025734 EspG family CU254_RS33470 cc0411cd2eaac5c57a4f0ee3bbc6958e 442 Gene3D G3DSA:3.50.50.60 9 162 1.9E-21 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS33470 cc0411cd2eaac5c57a4f0ee3bbc6958e 442 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 10 339 3.2E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS33470 cc0411cd2eaac5c57a4f0ee3bbc6958e 442 Gene3D G3DSA:3.40.50.720 163 388 2.0E-31 T 28-03-2018 CU254_RS33470 cc0411cd2eaac5c57a4f0ee3bbc6958e 442 SUPERFAMILY SSF51905 4 348 1.57E-29 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS33470 cc0411cd2eaac5c57a4f0ee3bbc6958e 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 7.2E-9 T 28-03-2018 CU254_RS33470 cc0411cd2eaac5c57a4f0ee3bbc6958e 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 108 126 7.2E-9 T 28-03-2018 CU254_RS33470 cc0411cd2eaac5c57a4f0ee3bbc6958e 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 168 186 7.2E-9 T 28-03-2018 CU254_RS24090 06e7a777053910bc8c221baec35f29a2 288 Gene3D G3DSA:3.40.190.10 174 263 5.6E-5 T 28-03-2018 CU254_RS24090 06e7a777053910bc8c221baec35f29a2 288 SUPERFAMILY SSF53850 89 284 1.3E-18 T 28-03-2018 CU254_RS24090 06e7a777053910bc8c221baec35f29a2 288 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 4.8E-21 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS24090 06e7a777053910bc8c221baec35f29a2 288 SUPERFAMILY SSF46785 1 84 1.09E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS24090 06e7a777053910bc8c221baec35f29a2 288 Pfam PF03466 LysR substrate binding domain 89 274 2.4E-16 T 28-03-2018 IPR005119 LysR, substrate-binding CU254_RS24090 06e7a777053910bc8c221baec35f29a2 288 Gene3D G3DSA:1.10.10.10 1 86 6.3E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS24090 06e7a777053910bc8c221baec35f29a2 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.2E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS24090 06e7a777053910bc8c221baec35f29a2 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.2E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS24090 06e7a777053910bc8c221baec35f29a2 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.2E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS24090 06e7a777053910bc8c221baec35f29a2 288 Gene3D G3DSA:3.40.190.10 87 173 4.7E-16 T 28-03-2018 CU254_RS30655 0650ea10d4d18d52978ca3d4d68da621 404 Gene3D G3DSA:2.30.40.10 351 404 0.012 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS30655 0650ea10d4d18d52978ca3d4d68da621 404 Gene3D G3DSA:3.20.20.140 67 350 1.1E-39 T 28-03-2018 CU254_RS30655 0650ea10d4d18d52978ca3d4d68da621 404 Pfam PF01979 Amidohydrolase family 50 392 6.9E-21 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CU254_RS30655 0650ea10d4d18d52978ca3d4d68da621 404 Gene3D G3DSA:2.30.40.10 3 66 4.8E-14 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS30655 0650ea10d4d18d52978ca3d4d68da621 404 SUPERFAMILY SSF51556 54 364 9.08E-50 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS30655 0650ea10d4d18d52978ca3d4d68da621 404 SUPERFAMILY SSF51338 365 386 5.91E-12 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS30655 0650ea10d4d18d52978ca3d4d68da621 404 SUPERFAMILY SSF51338 4 54 5.91E-12 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS34705 e60a60c274e283c004b91360c53b6363 542 ProSitePatterns PS00455 Putative AMP-binding domain signature. 182 193 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS34705 e60a60c274e283c004b91360c53b6363 542 Gene3D G3DSA:3.30.300.30 433 538 2.1E-28 T 28-03-2018 CU254_RS34705 e60a60c274e283c004b91360c53b6363 542 Gene3D G3DSA:3.40.50.980 188 348 6.4E-42 T 28-03-2018 CU254_RS34705 e60a60c274e283c004b91360c53b6363 542 Gene3D G3DSA:2.30.38.10 357 432 3.5E-15 T 28-03-2018 CU254_RS34705 e60a60c274e283c004b91360c53b6363 542 SUPERFAMILY SSF56801 10 534 1.02E-138 T 28-03-2018 CU254_RS34705 e60a60c274e283c004b91360c53b6363 542 Gene3D G3DSA:3.40.50.980 8 187 2.4E-35 T 28-03-2018 CU254_RS34705 e60a60c274e283c004b91360c53b6363 542 Pfam PF00501 AMP-binding enzyme 26 438 3.2E-90 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS34705 e60a60c274e283c004b91360c53b6363 542 Pfam PF13193 AMP-binding enzyme C-terminal domain 448 522 3.8E-19 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS26900 cacbb2b6497aeb3e17231068f0373c1f 158 Gene3D G3DSA:3.40.630.30 1 139 9.9E-26 T 28-03-2018 CU254_RS26900 cacbb2b6497aeb3e17231068f0373c1f 158 Pfam PF00583 Acetyltransferase (GNAT) family 37 137 4.1E-16 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS26900 cacbb2b6497aeb3e17231068f0373c1f 158 SUPERFAMILY SSF55729 3 142 1.01E-24 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS04220 1cba1ac42daf93e3f3777b893e07cfa5 455 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 16 451 1.4E-133 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CU254_RS04220 1cba1ac42daf93e3f3777b893e07cfa5 455 PIRSF PIRSF002746 11 455 6.7E-142 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CU254_RS04220 1cba1ac42daf93e3f3777b893e07cfa5 455 Pfam PF02447 GntP family permease 16 451 3.2E-141 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CU254_RS36390 a6e5f1df00195c955e4803057423d620 382 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 3 149 1.5E-12 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS36390 a6e5f1df00195c955e4803057423d620 382 Gene3D G3DSA:1.10.10.10 91 143 5.0E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS36390 a6e5f1df00195c955e4803057423d620 382 SUPERFAMILY SSF88659 91 149 8.72E-9 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS36390 a6e5f1df00195c955e4803057423d620 382 Gene3D G3DSA:1.10.1740.10 2 84 7.8E-16 T 28-03-2018 CU254_RS36390 a6e5f1df00195c955e4803057423d620 382 Pfam PF08281 Sigma-70, region 4 97 148 7.6E-9 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS36390 a6e5f1df00195c955e4803057423d620 382 Gene3D G3DSA:1.25.40.10 144 380 0.0045 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS36390 a6e5f1df00195c955e4803057423d620 382 Pfam PF04542 Sigma-70 region 2 5 70 4.7E-12 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS36390 a6e5f1df00195c955e4803057423d620 382 SUPERFAMILY SSF88946 3 84 2.39E-13 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS11600 62ffce6afbb76624ff8f7606da56c0b6 443 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 28 221 2.8E-86 T 28-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CU254_RS11600 62ffce6afbb76624ff8f7606da56c0b6 443 Hamap MF_01283 Riboflavin biosynthesis protein RibBA [ribBA]. 23 419 55.259 T 28-03-2018 IPR016299 Riboflavin biosynthesis protein RibBA GO:0009231 KEGG: 00740+3.5.4.25+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CU254_RS11600 62ffce6afbb76624ff8f7606da56c0b6 443 Pfam PF00925 GTP cyclohydrolase II 230 396 1.9E-69 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CU254_RS11600 62ffce6afbb76624ff8f7606da56c0b6 443 SUPERFAMILY SSF142695 228 399 1.7E-69 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CU254_RS11600 62ffce6afbb76624ff8f7606da56c0b6 443 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 25 222 6.4E-75 T 28-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CU254_RS11600 62ffce6afbb76624ff8f7606da56c0b6 443 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 230 420 6.5E-71 T 28-03-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CU254_RS11600 62ffce6afbb76624ff8f7606da56c0b6 443 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 227 423 40.412 T 28-03-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CU254_RS11600 62ffce6afbb76624ff8f7606da56c0b6 443 Gene3D G3DSA:3.90.870.10 16 235 3.5E-97 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CU254_RS11600 62ffce6afbb76624ff8f7606da56c0b6 443 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 22 226 38.292 T 28-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CU254_RS11600 62ffce6afbb76624ff8f7606da56c0b6 443 PIRSF PIRSF001259 22 430 1.3E-177 T 28-03-2018 CU254_RS11600 62ffce6afbb76624ff8f7606da56c0b6 443 SUPERFAMILY SSF55821 26 229 5.72E-82 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CU254_RS10120 76ca14cf73b8c2dbda66ed1781b77415 583 Pfam PF00553 Cellulose binding domain 490 581 2.5E-7 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CU254_RS10120 76ca14cf73b8c2dbda66ed1781b77415 583 SUPERFAMILY SSF49313 403 483 3.77E-13 T 28-03-2018 IPR015919 Cadherin-like GO:0005509|GO:0016020 CU254_RS10120 76ca14cf73b8c2dbda66ed1781b77415 583 Gene3D G3DSA:2.60.40.290 482 583 2.3E-13 T 28-03-2018 CU254_RS10120 76ca14cf73b8c2dbda66ed1781b77415 583 Gene3D G3DSA:3.40.50.200 66 391 5.1E-30 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS10120 76ca14cf73b8c2dbda66ed1781b77415 583 SUPERFAMILY SSF49384 485 579 3.21E-12 T 28-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 CU254_RS10120 76ca14cf73b8c2dbda66ed1781b77415 583 SUPERFAMILY SSF52743 84 387 5.5E-42 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS10120 76ca14cf73b8c2dbda66ed1781b77415 583 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 318 328 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CU254_RS10120 76ca14cf73b8c2dbda66ed1781b77415 583 SMART SM00637 489 582 8.2E-5 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CU254_RS10120 76ca14cf73b8c2dbda66ed1781b77415 583 Gene3D G3DSA:2.60.40.10 394 481 9.0E-17 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS10120 76ca14cf73b8c2dbda66ed1781b77415 583 Pfam PF05345 Putative Ig domain 430 470 1.9E-11 T 28-03-2018 IPR008009 Putative Ig CU254_RS20235 c6247644f5fbe928b58d6b2a98ad8d23 127 Gene3D G3DSA:2.40.50.100 5 127 1.9E-48 T 28-03-2018 CU254_RS20235 c6247644f5fbe928b58d6b2a98ad8d23 127 SUPERFAMILY SSF51230 3 126 2.75E-44 T 28-03-2018 IPR011053 Single hybrid motif CU254_RS20235 c6247644f5fbe928b58d6b2a98ad8d23 127 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 125 1.4E-50 T 28-03-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 CU254_RS20235 c6247644f5fbe928b58d6b2a98ad8d23 127 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 4 126 40.786 T 28-03-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 CU254_RS20235 c6247644f5fbe928b58d6b2a98ad8d23 127 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 48 77 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CU254_RS20235 c6247644f5fbe928b58d6b2a98ad8d23 127 Pfam PF01597 Glycine cleavage H-protein 7 126 1.4E-45 T 28-03-2018 IPR033753 Glycine cleavage system H-protein/Simiate CU254_RS07630 28a48d0977e8ee5a5a515d3e87ff58a6 547 Pfam PF00754 F5/8 type C domain 49 161 6.5E-23 T 28-03-2018 IPR000421 Coagulation factor 5/8 C-terminal domain CU254_RS07630 28a48d0977e8ee5a5a515d3e87ff58a6 547 Pfam PF00149 Calcineurin-like phosphoesterase 292 466 8.4E-13 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CU254_RS07630 28a48d0977e8ee5a5a515d3e87ff58a6 547 Gene3D G3DSA:2.60.40.10 159 259 3.4E-22 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS07630 28a48d0977e8ee5a5a515d3e87ff58a6 547 Pfam PF00041 Fibronectin type III domain 179 253 2.1E-7 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CU254_RS07630 28a48d0977e8ee5a5a515d3e87ff58a6 547 SUPERFAMILY SSF49785 45 167 9.22E-27 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS07630 28a48d0977e8ee5a5a515d3e87ff58a6 547 SMART SM00060 177 250 3.7E-11 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CU254_RS07630 28a48d0977e8ee5a5a515d3e87ff58a6 547 Gene3D G3DSA:2.60.120.260 29 158 1.4E-33 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS07630 28a48d0977e8ee5a5a515d3e87ff58a6 547 SUPERFAMILY SSF49265 174 263 9.68E-18 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CU254_RS07630 28a48d0977e8ee5a5a515d3e87ff58a6 547 Gene3D G3DSA:3.60.21.10 268 545 1.1E-37 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CU254_RS07630 28a48d0977e8ee5a5a515d3e87ff58a6 547 SUPERFAMILY SSF56300 294 539 2.34E-43 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CU254_RS19460 cf61ffc5a4b688178a7d499bb5076c11 299 SUPERFAMILY SSF141986 142 287 1.01E-35 T 28-03-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain CU254_RS19460 cf61ffc5a4b688178a7d499bb5076c11 299 Gene3D G3DSA:3.50.30.60 150 297 6.1E-37 T 28-03-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain CU254_RS19460 cf61ffc5a4b688178a7d499bb5076c11 299 PIRSF PIRSF028757 1 299 3.4E-68 T 28-03-2018 IPR003507 Peptidase family S66 CU254_RS19460 cf61ffc5a4b688178a7d499bb5076c11 299 Gene3D G3DSA:3.40.50.10740 1 149 2.2E-45 T 28-03-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal domain CU254_RS19460 cf61ffc5a4b688178a7d499bb5076c11 299 Pfam PF02016 LD-carboxypeptidase 12 284 3.6E-69 T 28-03-2018 IPR003507 Peptidase family S66 CU254_RS19460 cf61ffc5a4b688178a7d499bb5076c11 299 SUPERFAMILY SSF52317 2 157 7.32E-38 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS06460 234bde6ea8c1834de36b6562d255f56f 100 Gene3D G3DSA:3.30.70.930 1 96 3.2E-31 T 28-03-2018 IPR029756 MTH1187/YkoF-like CU254_RS06460 234bde6ea8c1834de36b6562d255f56f 100 Pfam PF01910 Thiamine-binding protein 3 94 6.5E-26 T 28-03-2018 IPR002767 Thiamine-binding protein CU254_RS06460 234bde6ea8c1834de36b6562d255f56f 100 SUPERFAMILY SSF89957 2 99 2.75E-26 T 28-03-2018 IPR029756 MTH1187/YkoF-like CU254_RS17890 8bf998e1661f72d91ded36c7d6accd25 441 Gene3D G3DSA:3.20.20.70 53 363 1.1E-31 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS17890 8bf998e1661f72d91ded36c7d6accd25 441 Pfam PF01595 Domain of unknown function DUF21 12 205 1.5E-31 T 28-03-2018 IPR002550 Domain of unknown function DUF21 CU254_RS17890 8bf998e1661f72d91ded36c7d6accd25 441 Gene3D G3DSA:3.30.465.10 364 436 1.9E-29 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CU254_RS17890 8bf998e1661f72d91ded36c7d6accd25 441 Pfam PF00571 CBS domain 293 341 2.1E-6 T 28-03-2018 IPR000644 CBS domain CU254_RS17890 8bf998e1661f72d91ded36c7d6accd25 441 Pfam PF00571 CBS domain 224 271 0.0047 T 28-03-2018 IPR000644 CBS domain CU254_RS17890 8bf998e1661f72d91ded36c7d6accd25 441 SUPERFAMILY SSF54631 212 352 5.31E-30 T 28-03-2018 CU254_RS17890 8bf998e1661f72d91ded36c7d6accd25 441 SMART SM01091 358 436 7.1E-27 T 28-03-2018 IPR005170 Transporter-associated domain CU254_RS17890 8bf998e1661f72d91ded36c7d6accd25 441 SUPERFAMILY SSF56176 357 438 2.43E-22 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CU254_RS17890 8bf998e1661f72d91ded36c7d6accd25 441 Pfam PF03471 Transporter associated domain 359 434 2.6E-24 T 28-03-2018 IPR005170 Transporter-associated domain CU254_RS13970 965b7a962bdcc9f207cb68f8edfd6116 165 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 3 151 1.4E-50 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CU254_RS13970 965b7a962bdcc9f207cb68f8edfd6116 165 Gene3D G3DSA:3.30.1060.10 1 165 4.5E-67 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CU254_RS13970 965b7a962bdcc9f207cb68f8edfd6116 165 Pfam PF01625 Peptide methionine sulfoxide reductase 4 151 2.7E-58 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CU254_RS13970 965b7a962bdcc9f207cb68f8edfd6116 165 SUPERFAMILY SSF55068 2 159 1.57E-65 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CU254_RS13970 965b7a962bdcc9f207cb68f8edfd6116 165 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 2 157 33.95 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CU254_RS12630 3f9badcba8d037c133a729e4e0672fd8 281 Pfam PF16708 Lipoprotein confined to pathogenic Mycobacterium 125 267 1.4E-29 T 28-03-2018 IPR032018 Putative lipoprotein, pathogenic bacteria CU254_RS10995 5ef9d968fdceebdb4843223ab9621bdf 274 Pfam PF13556 PucR C-terminal helix-turn-helix domain 215 272 1.1E-20 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CU254_RS10995 5ef9d968fdceebdb4843223ab9621bdf 274 Gene3D G3DSA:1.10.10.60 199 251 2.2E-7 T 28-03-2018 CU254_RS15710 162f991a72d77da6adde6f1fec71b78b 422 SUPERFAMILY SSF51905 288 390 1.2E-62 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS15710 162f991a72d77da6adde6f1fec71b78b 422 SUPERFAMILY SSF51905 7 182 1.2E-62 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS15710 162f991a72d77da6adde6f1fec71b78b 422 SUPERFAMILY SSF54373 187 291 4.71E-16 T 28-03-2018 CU254_RS15710 162f991a72d77da6adde6f1fec71b78b 422 Gene3D G3DSA:3.50.50.60 2 396 2.6E-50 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS15710 162f991a72d77da6adde6f1fec71b78b 422 Pfam PF01494 FAD binding domain 8 364 2.1E-25 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CU254_RS15710 162f991a72d77da6adde6f1fec71b78b 422 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 161 176 4.2E-19 T 28-03-2018 CU254_RS15710 162f991a72d77da6adde6f1fec71b78b 422 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 301 316 4.2E-19 T 28-03-2018 CU254_RS15710 162f991a72d77da6adde6f1fec71b78b 422 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 8 30 4.2E-19 T 28-03-2018 CU254_RS15710 162f991a72d77da6adde6f1fec71b78b 422 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 316 332 4.2E-19 T 28-03-2018 CU254_RS34185 57a25f30064724d0b4a54d2aeedcf778 349 SUPERFAMILY SSF47384 109 188 7.06E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS34185 57a25f30064724d0b4a54d2aeedcf778 349 SMART SM00387 233 348 1.6E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS34185 57a25f30064724d0b4a54d2aeedcf778 349 SUPERFAMILY SSF55874 178 346 1.23E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS34185 57a25f30064724d0b4a54d2aeedcf778 349 Gene3D G3DSA:1.10.287.130 111 182 1.9E-14 T 28-03-2018 CU254_RS34185 57a25f30064724d0b4a54d2aeedcf778 349 Pfam PF00512 His Kinase A (phospho-acceptor) domain 121 188 1.2E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS34185 57a25f30064724d0b4a54d2aeedcf778 349 Gene3D G3DSA:3.30.565.10 183 348 5.0E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS34185 57a25f30064724d0b4a54d2aeedcf778 349 PRINTS PR00344 Bacterial sensor protein C-terminal signature 332 345 9.0E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS34185 57a25f30064724d0b4a54d2aeedcf778 349 PRINTS PR00344 Bacterial sensor protein C-terminal signature 309 327 9.0E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS34185 57a25f30064724d0b4a54d2aeedcf778 349 PRINTS PR00344 Bacterial sensor protein C-terminal signature 270 284 9.0E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS34185 57a25f30064724d0b4a54d2aeedcf778 349 SMART SM00388 121 188 6.0E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS34185 57a25f30064724d0b4a54d2aeedcf778 349 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 236 347 1.1E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS08145 82f9b04c16f6bbb33f61b82b6fe481d6 190 Gene3D G3DSA:3.90.70.10 26 188 2.2E-26 T 28-03-2018 CU254_RS08145 82f9b04c16f6bbb33f61b82b6fe481d6 190 Pfam PF12385 Papain-like cysteine protease AvrRpt2 32 169 1.1E-20 T 28-03-2018 IPR022118 Peptidase C70, AvrRpt2 CU254_RS18385 7dba35aae5f1edd7b9243c3cd86a127d 284 SUPERFAMILY SSF51735 7 241 2.77E-59 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS18385 7dba35aae5f1edd7b9243c3cd86a127d 284 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 1.9E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18385 7dba35aae5f1edd7b9243c3cd86a127d 284 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 1.9E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18385 7dba35aae5f1edd7b9243c3cd86a127d 284 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 1.9E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18385 7dba35aae5f1edd7b9243c3cd86a127d 284 Pfam PF00106 short chain dehydrogenase 10 191 6.5E-47 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18385 7dba35aae5f1edd7b9243c3cd86a127d 284 Gene3D G3DSA:3.40.50.720 5 282 1.1E-59 T 28-03-2018 CU254_RS18385 7dba35aae5f1edd7b9243c3cd86a127d 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 4.0E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18385 7dba35aae5f1edd7b9243c3cd86a127d 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 4.0E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18385 7dba35aae5f1edd7b9243c3cd86a127d 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 4.0E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18385 7dba35aae5f1edd7b9243c3cd86a127d 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 4.0E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18385 7dba35aae5f1edd7b9243c3cd86a127d 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 4.0E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS35940 01608b702991f5ecdf85fe2432805429 845 Pfam PF02358 Trehalose-phosphatase 28 217 1.7E-29 T 28-03-2018 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 CU254_RS35940 01608b702991f5ecdf85fe2432805429 845 Gene3D G3DSA:3.40.50.1000 23 262 1.3E-18 T 28-03-2018 IPR023214 HAD-like domain CU254_RS35940 01608b702991f5ecdf85fe2432805429 845 SUPERFAMILY SSF56784 25 251 6.53E-34 T 28-03-2018 IPR023214 HAD-like domain CU254_RS35940 01608b702991f5ecdf85fe2432805429 845 Pfam PF00723 Glycosyl hydrolases family 15 476 785 3.8E-29 T 28-03-2018 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: R-HSA-70221 CU254_RS35940 01608b702991f5ecdf85fe2432805429 845 Gene3D G3DSA:1.50.10.10 795 845 0.011 T 28-03-2018 CU254_RS35940 01608b702991f5ecdf85fe2432805429 845 Gene3D G3DSA:1.50.10.10 446 794 4.9E-78 T 28-03-2018 CU254_RS35940 01608b702991f5ecdf85fe2432805429 845 TIGRFAM TIGR00685 T6PP: trehalose-phosphatase 24 251 8.5E-35 T 28-03-2018 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 CU254_RS35940 01608b702991f5ecdf85fe2432805429 845 SUPERFAMILY SSF48208 462 843 9.87E-91 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CU254_RS29290 7a1d4d8ea27bc2fdac1c80837dc52d10 484 Gene3D G3DSA:1.20.140.10 289 480 2.9E-51 T 28-03-2018 CU254_RS29290 7a1d4d8ea27bc2fdac1c80837dc52d10 484 Gene3D G3DSA:2.40.110.10 152 279 2.2E-16 T 28-03-2018 CU254_RS29290 7a1d4d8ea27bc2fdac1c80837dc52d10 484 Pfam PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal 295 479 1.9E-43 T 28-03-2018 IPR024719 HpaB/PvcC/4-BUDH C-terminal CU254_RS29290 7a1d4d8ea27bc2fdac1c80837dc52d10 484 SUPERFAMILY SSF56645 10 277 9.42E-65 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS29290 7a1d4d8ea27bc2fdac1c80837dc52d10 484 PIRSF PIRSF000331 7 483 9.1E-115 T 28-03-2018 IPR004925 HpaB/PvcC/4-BUDH CU254_RS29290 7a1d4d8ea27bc2fdac1c80837dc52d10 484 Pfam PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal 11 277 8.6E-77 T 28-03-2018 IPR024674 HpaB/PvcC/4-BUDH N-terminal CU254_RS29290 7a1d4d8ea27bc2fdac1c80837dc52d10 484 Gene3D G3DSA:1.10.3140.10 10 151 9.2E-38 T 28-03-2018 CU254_RS29290 7a1d4d8ea27bc2fdac1c80837dc52d10 484 SUPERFAMILY SSF47203 268 479 1.76E-38 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS34360 f7a3340d4740056733500d1389444932 384 Gene3D G3DSA:3.40.50.300 1 362 5.8E-25 T 28-03-2018 CU254_RS34360 f7a3340d4740056733500d1389444932 384 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 249 348 1.0E-18 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CU254_RS34360 f7a3340d4740056733500d1389444932 384 PIRSF PIRSF029347 1 384 4.3E-136 T 28-03-2018 IPR014555 RecF-like CU254_RS34360 f7a3340d4740056733500d1389444932 384 SUPERFAMILY SSF52540 2 134 3.01E-24 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS34360 f7a3340d4740056733500d1389444932 384 SUPERFAMILY SSF52540 258 360 3.01E-24 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS34360 f7a3340d4740056733500d1389444932 384 Pfam PF13175 AAA ATPase domain 2 47 6.0E-11 T 28-03-2018 CU254_RS09115 adcf83ab41974f4eeaca7acce2b9002f 317 Pfam PF01037 Lrp/AsnC ligand binding domain 243 308 2.8E-10 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CU254_RS09115 adcf83ab41974f4eeaca7acce2b9002f 317 Gene3D G3DSA:1.10.10.10 1 48 1.5E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS09115 adcf83ab41974f4eeaca7acce2b9002f 317 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 29 48 1.8E-5 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS09115 adcf83ab41974f4eeaca7acce2b9002f 317 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 2 18 1.8E-5 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS09115 adcf83ab41974f4eeaca7acce2b9002f 317 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 18 29 1.8E-5 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS09115 adcf83ab41974f4eeaca7acce2b9002f 317 Pfam PF13404 AsnC-type helix-turn-helix domain 2 43 3.5E-16 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS09115 adcf83ab41974f4eeaca7acce2b9002f 317 Pfam PF13404 AsnC-type helix-turn-helix domain 176 213 2.5E-9 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS09115 adcf83ab41974f4eeaca7acce2b9002f 317 SMART SM00344 2 106 7.8E-4 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CU254_RS09115 adcf83ab41974f4eeaca7acce2b9002f 317 SMART SM00344 176 277 3.4E-5 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CU254_RS09115 adcf83ab41974f4eeaca7acce2b9002f 317 Gene3D G3DSA:3.30.70.920 224 316 9.3E-16 T 28-03-2018 CU254_RS09115 adcf83ab41974f4eeaca7acce2b9002f 317 SUPERFAMILY SSF54909 234 310 1.47E-10 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS09115 adcf83ab41974f4eeaca7acce2b9002f 317 Gene3D G3DSA:1.10.10.10 149 217 3.5E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS09115 adcf83ab41974f4eeaca7acce2b9002f 317 SUPERFAMILY SSF46785 1 45 6.3E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS09115 adcf83ab41974f4eeaca7acce2b9002f 317 SUPERFAMILY SSF46785 170 222 1.08E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS01980 3c209e351476ef294b566cb59ceb2795 281 Pfam PF07650 KH domain 37 109 7.8E-19 T 28-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS01980 3c209e351476ef294b566cb59ceb2795 281 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 206 37.77 T 28-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 CU254_RS01980 3c209e351476ef294b566cb59ceb2795 281 SMART SM00322 59 124 4.1E-7 T 28-03-2018 IPR004087 K Homology domain GO:0003676 CU254_RS01980 3c209e351476ef294b566cb59ceb2795 281 SUPERFAMILY SSF54814 2 105 1.18E-36 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CU254_RS01980 3c209e351476ef294b566cb59ceb2795 281 ProSitePatterns PS00548 Ribosomal protein S3 signature. 163 197 - T 28-03-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS01980 3c209e351476ef294b566cb59ceb2795 281 Gene3D G3DSA:3.30.300.20 17 106 2.4E-31 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CU254_RS01980 3c209e351476ef294b566cb59ceb2795 281 Pfam PF00189 Ribosomal protein S3, C-terminal domain 119 202 4.4E-35 T 28-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS01980 3c209e351476ef294b566cb59ceb2795 281 SUPERFAMILY SSF54821 106 206 1.57E-35 T 28-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS01980 3c209e351476ef294b566cb59ceb2795 281 Gene3D G3DSA:3.30.1140.32 107 207 2.8E-34 T 28-03-2018 CU254_RS01980 3c209e351476ef294b566cb59ceb2795 281 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 208 1.0E-92 T 28-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 CU254_RS33195 79d989b80dd97a060668d934a42b47eb 458 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 361 369 - T 28-03-2018 IPR018120 Glycoside hydrolase family 1, active site CU254_RS33195 79d989b80dd97a060668d934a42b47eb 458 PRINTS PR00131 Glycosyl hydrolase family 1 signature 402 419 1.5E-21 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CU254_RS33195 79d989b80dd97a060668d934a42b47eb 458 PRINTS PR00131 Glycosyl hydrolase family 1 signature 426 438 1.5E-21 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CU254_RS33195 79d989b80dd97a060668d934a42b47eb 458 PRINTS PR00131 Glycosyl hydrolase family 1 signature 288 302 1.5E-21 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CU254_RS33195 79d989b80dd97a060668d934a42b47eb 458 PRINTS PR00131 Glycosyl hydrolase family 1 signature 381 392 1.5E-21 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CU254_RS33195 79d989b80dd97a060668d934a42b47eb 458 PRINTS PR00131 Glycosyl hydrolase family 1 signature 361 369 1.5E-21 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CU254_RS33195 79d989b80dd97a060668d934a42b47eb 458 Pfam PF00232 Glycosyl hydrolase family 1 11 455 6.6E-150 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CU254_RS33195 79d989b80dd97a060668d934a42b47eb 458 SUPERFAMILY SSF51445 11 456 1.91E-154 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS33195 79d989b80dd97a060668d934a42b47eb 458 Gene3D G3DSA:3.20.20.80 10 457 1.4E-158 T 28-03-2018 CU254_RS33195 79d989b80dd97a060668d934a42b47eb 458 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 16 30 - T 28-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site CU254_RS33195 79d989b80dd97a060668d934a42b47eb 458 TIGRFAM TIGR03356 BGL: beta-galactosidase 12 448 3.7E-174 T 28-03-2018 IPR017736 Glycoside hydrolase, family 1, beta-glucosidase GO:0008422|GO:0030245 KEGG: 00460+3.2.1.21|KEGG: 00500+3.2.1.21|KEGG: 00940+3.2.1.21|MetaCyc: PWY-3121|MetaCyc: PWY-5176|MetaCyc: PWY-6002|MetaCyc: PWY-6788|MetaCyc: PWY-7091|MetaCyc: PWY-7092 CU254_RS11030 bb3b67311567fcf578b20036ed827efa 399 Pfam PF02803 Thiolase, C-terminal domain 269 388 1.2E-35 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CU254_RS11030 bb3b67311567fcf578b20036ed827efa 399 Pfam PF00108 Thiolase, N-terminal domain 4 257 3.3E-57 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CU254_RS11030 bb3b67311567fcf578b20036ed827efa 399 Gene3D G3DSA:3.40.47.10 1 268 2.2E-44 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS11030 bb3b67311567fcf578b20036ed827efa 399 Gene3D G3DSA:3.40.47.10 269 387 3.4E-25 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS11030 bb3b67311567fcf578b20036ed827efa 399 SUPERFAMILY SSF53901 3 264 6.56E-59 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS11030 bb3b67311567fcf578b20036ed827efa 399 SUPERFAMILY SSF53901 268 388 1.6E-38 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS11030 bb3b67311567fcf578b20036ed827efa 399 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 388 7.1E-125 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CU254_RS11030 bb3b67311567fcf578b20036ed827efa 399 ProSitePatterns PS00737 Thiolases signature 2. 335 351 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CU254_RS11030 bb3b67311567fcf578b20036ed827efa 399 PIRSF PIRSF000429 1 391 9.4E-121 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CU254_RS39690 8637e06e1d2d28b826a3773058fe2ae5 219 ProSitePatterns PS01081 TetR-type HTH domain signature. 50 81 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CU254_RS39690 8637e06e1d2d28b826a3773058fe2ae5 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 51 7.6E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS39690 8637e06e1d2d28b826a3773058fe2ae5 219 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 59 82 7.6E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS39690 8637e06e1d2d28b826a3773058fe2ae5 219 Gene3D G3DSA:1.10.10.60 23 59 4.0E-14 T 28-03-2018 CU254_RS39690 8637e06e1d2d28b826a3773058fe2ae5 219 SUPERFAMILY SSF46689 28 102 6.98E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS39690 8637e06e1d2d28b826a3773058fe2ae5 219 Gene3D G3DSA:1.10.260.40 60 89 1.4E-11 T 28-03-2018 CU254_RS39690 8637e06e1d2d28b826a3773058fe2ae5 219 Pfam PF00440 Bacterial regulatory proteins, tetR family 39 84 7.0E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS39690 8637e06e1d2d28b826a3773058fe2ae5 219 Gene3D G3DSA:1.10.357.10 90 217 2.3E-8 T 28-03-2018 CU254_RS00355 e26a1127e3800ad184dfa9ae55551390 110 Gene3D G3DSA:1.10.1660.10 17 109 6.0E-20 T 28-03-2018 CU254_RS00355 e26a1127e3800ad184dfa9ae55551390 110 SUPERFAMILY SSF46955 25 107 7.33E-14 T 28-03-2018 IPR009061 Putative DNA-binding domain CU254_RS00355 e26a1127e3800ad184dfa9ae55551390 110 Pfam PF13411 MerR HTH family regulatory protein 25 87 8.5E-12 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS00355 e26a1127e3800ad184dfa9ae55551390 110 SMART SM00422 25 93 5.0E-11 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS36690 92bc0c5e03969f9118925ad7edc89d1a 95 Pfam PF00550 Phosphopantetheine attachment site 23 85 2.2E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS36690 92bc0c5e03969f9118925ad7edc89d1a 95 SMART SM00823 Phosphopantetheine attachment site 21 74 0.01 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS36690 92bc0c5e03969f9118925ad7edc89d1a 95 SUPERFAMILY SSF47336 17 93 6.15E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS36690 92bc0c5e03969f9118925ad7edc89d1a 95 Gene3D G3DSA:1.10.1200.10 1 94 2.2E-17 T 28-03-2018 CU254_RS40060 075feab077e75f961b024d35e6d39e58 1104 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 551 1076 3.1E-119 T 28-03-2018 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0006810|GO:0016021|GO:0042626 CU254_RS40060 075feab077e75f961b024d35e6d39e58 1104 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 21 519 1.8E-138 T 28-03-2018 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 CU254_RS40060 075feab077e75f961b024d35e6d39e58 1104 Pfam PF00664 ABC transporter transmembrane region 25 275 1.7E-26 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CU254_RS40060 075feab077e75f961b024d35e6d39e58 1104 ProSitePatterns PS00211 ABC transporters family signature. 1017 1031 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS40060 075feab077e75f961b024d35e6d39e58 1104 SUPERFAMILY SSF52540 898 1095 7.01E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS40060 075feab077e75f961b024d35e6d39e58 1104 SUPERFAMILY SSF90123 19 324 4.45E-50 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CU254_RS40060 075feab077e75f961b024d35e6d39e58 1104 Gene3D G3DSA:3.40.50.300 896 1101 9.5E-49 T 28-03-2018 CU254_RS40060 075feab077e75f961b024d35e6d39e58 1104 ProSitePatterns PS00211 ABC transporters family signature. 454 468 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS40060 075feab077e75f961b024d35e6d39e58 1104 SMART SM00382 924 1093 3.5E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS40060 075feab077e75f961b024d35e6d39e58 1104 SMART SM00382 360 559 1.7E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS40060 075feab077e75f961b024d35e6d39e58 1104 Gene3D G3DSA:3.40.50.300 327 544 9.0E-39 T 28-03-2018 CU254_RS40060 075feab077e75f961b024d35e6d39e58 1104 SUPERFAMILY SSF90123 551 832 8.76E-25 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CU254_RS40060 075feab077e75f961b024d35e6d39e58 1104 SUPERFAMILY SSF52540 335 524 1.73E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS40060 075feab077e75f961b024d35e6d39e58 1104 Pfam PF00005 ABC transporter 915 1047 4.9E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS40060 075feab077e75f961b024d35e6d39e58 1104 Pfam PF00005 ABC transporter 355 485 5.3E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS40060 075feab077e75f961b024d35e6d39e58 1104 Gene3D G3DSA:1.20.1560.10 4 326 3.2E-42 T 28-03-2018 CU254_RS40060 075feab077e75f961b024d35e6d39e58 1104 Gene3D G3DSA:1.20.1560.10 545 842 2.4E-15 T 28-03-2018 CU254_RS00775 f7d07cf791182cce471f921a23811720 479 Gene3D G3DSA:3.90.1300.10 1 470 3.1E-99 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS00775 f7d07cf791182cce471f921a23811720 479 Pfam PF01425 Amidase 25 446 3.8E-77 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS00775 f7d07cf791182cce471f921a23811720 479 ProSitePatterns PS00571 Amidases signature. 153 184 - T 28-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CU254_RS00775 f7d07cf791182cce471f921a23811720 479 SUPERFAMILY SSF75304 2 458 2.75E-101 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS09860 fcd18971675ea1422d4c2c8fb8aa5265 369 Gene3D G3DSA:1.25.20.10 44 343 1.6E-4 T 28-03-2018 CU254_RS09860 fcd18971675ea1422d4c2c8fb8aa5265 369 Pfam PF13830 Domain of unknown function (DUF4192) 17 328 1.2E-69 T 28-03-2018 IPR025447 Protein of unknown function DUF4192 CU254_RS06015 c7700189a9299ae26de68401600d9751 575 SUPERFAMILY SSF53383 11 366 3.73E-50 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS06015 c7700189a9299ae26de68401600d9751 575 Pfam PF13309 HTH domain 513 570 2.8E-18 T 28-03-2018 CU254_RS06015 c7700189a9299ae26de68401600d9751 575 Pfam PF08348 YheO-like PAS domain 385 489 1.2E-29 T 28-03-2018 IPR013559 YheO-like CU254_RS06015 c7700189a9299ae26de68401600d9751 575 Pfam PF00266 Aminotransferase class-V 87 335 3.4E-23 T 28-03-2018 IPR000192 Aminotransferase class V domain CU254_RS06015 c7700189a9299ae26de68401600d9751 575 ProDom PD037769 DNA-BINDING YHEO UNCHARACTERIZED BACTERIA SIMILAR HI0575 CONTAINING TRANSCRIPTION REGULATOR HELIX-TURN-HELIX 383 483 9.0E-19 T 28-03-2018 IPR013559 YheO-like CU254_RS06015 c7700189a9299ae26de68401600d9751 575 Gene3D G3DSA:3.40.640.10 40 265 1.1E-22 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS06015 c7700189a9299ae26de68401600d9751 575 Gene3D G3DSA:3.90.1150.10 266 376 1.1E-10 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS11995 982a04bbddf6c6d2680c143819496b09 991 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 735 757 - T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CU254_RS11995 982a04bbddf6c6d2680c143819496b09 991 SUPERFAMILY SSF48168 138 354 5.36E-58 T 28-03-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CU254_RS11995 982a04bbddf6c6d2680c143819496b09 991 PRINTS PR01183 Ribonucleotide reductase large chain signature 431 450 1.7E-46 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CU254_RS11995 982a04bbddf6c6d2680c143819496b09 991 PRINTS PR01183 Ribonucleotide reductase large chain signature 603 626 1.7E-46 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CU254_RS11995 982a04bbddf6c6d2680c143819496b09 991 PRINTS PR01183 Ribonucleotide reductase large chain signature 746 773 1.7E-46 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CU254_RS11995 982a04bbddf6c6d2680c143819496b09 991 PRINTS PR01183 Ribonucleotide reductase large chain signature 641 663 1.7E-46 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CU254_RS11995 982a04bbddf6c6d2680c143819496b09 991 PRINTS PR01183 Ribonucleotide reductase large chain signature 669 692 1.7E-46 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CU254_RS11995 982a04bbddf6c6d2680c143819496b09 991 PRINTS PR01183 Ribonucleotide reductase large chain signature 566 577 1.7E-46 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CU254_RS11995 982a04bbddf6c6d2680c143819496b09 991 Pfam PF02867 Ribonucleotide reductase, barrel domain 356 891 1.3E-183 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CU254_RS11995 982a04bbddf6c6d2680c143819496b09 991 Gene3D G3DSA:3.20.70.20 259 899 3.4E-214 T 28-03-2018 CU254_RS11995 982a04bbddf6c6d2680c143819496b09 991 SUPERFAMILY SSF51998 355 795 4.88E-181 T 28-03-2018 CU254_RS11995 982a04bbddf6c6d2680c143819496b09 991 SUPERFAMILY SSF51998 826 896 4.88E-181 T 28-03-2018 CU254_RS11995 982a04bbddf6c6d2680c143819496b09 991 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 288 890 1.5E-120 T 28-03-2018 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CU254_RS11995 982a04bbddf6c6d2680c143819496b09 991 Pfam PF03477 ATP cone domain 21 117 1.6E-18 T 28-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 CU254_RS11995 982a04bbddf6c6d2680c143819496b09 991 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 279 352 9.0E-21 T 28-03-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CU254_RS11995 982a04bbddf6c6d2680c143819496b09 991 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 283 894 4.5E-213 T 28-03-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CU254_RS37345 6bac524469d2dd84db4a66e11dc2669e 165 SUPERFAMILY SSF46785 15 68 1.14E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS37345 6bac524469d2dd84db4a66e11dc2669e 165 SMART SM00344 18 122 5.2E-25 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CU254_RS37345 6bac524469d2dd84db4a66e11dc2669e 165 Gene3D G3DSA:1.10.10.10 14 69 7.0E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS37345 6bac524469d2dd84db4a66e11dc2669e 165 Pfam PF13404 AsnC-type helix-turn-helix domain 18 58 3.6E-17 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS37345 6bac524469d2dd84db4a66e11dc2669e 165 Gene3D G3DSA:3.30.70.920 70 161 7.8E-14 T 28-03-2018 CU254_RS37345 6bac524469d2dd84db4a66e11dc2669e 165 Pfam PF01037 Lrp/AsnC ligand binding domain 83 152 5.9E-10 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CU254_RS37345 6bac524469d2dd84db4a66e11dc2669e 165 SUPERFAMILY SSF54909 80 154 4.29E-11 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS37345 6bac524469d2dd84db4a66e11dc2669e 165 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 18 34 1.2E-11 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS37345 6bac524469d2dd84db4a66e11dc2669e 165 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 45 64 1.2E-11 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS37345 6bac524469d2dd84db4a66e11dc2669e 165 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 34 45 1.2E-11 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS16135 c55433fc8212acacb64866bec43185e4 195 Gene3D G3DSA:1.10.10.10 116 195 5.6E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS16135 c55433fc8212acacb64866bec43185e4 195 SMART SM00421 132 189 3.4E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS16135 c55433fc8212acacb64866bec43185e4 195 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 177 3.2E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS16135 c55433fc8212acacb64866bec43185e4 195 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 135 149 3.2E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS16135 c55433fc8212acacb64866bec43185e4 195 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 165 3.2E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS16135 c55433fc8212acacb64866bec43185e4 195 Gene3D G3DSA:3.40.50.2300 46 115 4.8E-7 T 28-03-2018 CU254_RS16135 c55433fc8212acacb64866bec43185e4 195 SUPERFAMILY SSF46894 116 195 9.18E-17 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS16135 c55433fc8212acacb64866bec43185e4 195 Pfam PF00196 Bacterial regulatory proteins, luxR family 134 189 1.5E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS38195 fd38449184e3d2f1802b725d0971c12e 128 Pfam PF10861 Protein of Unknown function (DUF2784) 4 110 5.2E-28 T 28-03-2018 IPR021218 Protein of unknown function DUF2784 CU254_RS10545 9a086a49e5273879c27deaf918152a23 376 ProSitePatterns PS00737 Thiolases signature 2. 322 338 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CU254_RS10545 9a086a49e5273879c27deaf918152a23 376 SUPERFAMILY SSF53901 254 375 1.54E-38 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS10545 9a086a49e5273879c27deaf918152a23 376 Gene3D G3DSA:3.40.47.10 257 373 2.3E-25 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS10545 9a086a49e5273879c27deaf918152a23 376 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 374 1.9E-116 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CU254_RS10545 9a086a49e5273879c27deaf918152a23 376 PIRSF PIRSF000429 2 376 5.7E-114 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CU254_RS10545 9a086a49e5273879c27deaf918152a23 376 Pfam PF02803 Thiolase, C-terminal domain 254 375 3.6E-41 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CU254_RS10545 9a086a49e5273879c27deaf918152a23 376 SUPERFAMILY SSF53901 4 253 1.09E-63 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS10545 9a086a49e5273879c27deaf918152a23 376 Pfam PF00108 Thiolase, N-terminal domain 5 245 7.8E-59 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CU254_RS10545 9a086a49e5273879c27deaf918152a23 376 Gene3D G3DSA:3.40.47.10 2 145 8.8E-26 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS10545 9a086a49e5273879c27deaf918152a23 376 Gene3D G3DSA:3.40.47.10 146 256 3.8E-19 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS10545 9a086a49e5273879c27deaf918152a23 376 ProSitePatterns PS00099 Thiolases active site. 357 370 - T 28-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CU254_RS33585 48cc2d2170011c6a0027fc3080bcbc5e 428 SUPERFAMILY SSF51604 138 418 3.4E-125 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CU254_RS33585 48cc2d2170011c6a0027fc3080bcbc5e 428 SUPERFAMILY SSF54826 4 136 2.55E-51 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CU254_RS33585 48cc2d2170011c6a0027fc3080bcbc5e 428 SMART SM01193 4 134 4.3E-84 T 28-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CU254_RS33585 48cc2d2170011c6a0027fc3080bcbc5e 428 Pfam PF03952 Enolase, N-terminal domain 4 134 2.2E-56 T 28-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CU254_RS33585 48cc2d2170011c6a0027fc3080bcbc5e 428 Gene3D G3DSA:3.20.20.120 128 427 1.6E-98 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CU254_RS33585 48cc2d2170011c6a0027fc3080bcbc5e 428 Hamap MF_00318 Enolase [eno]. 2 409 45.54 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CU254_RS33585 48cc2d2170011c6a0027fc3080bcbc5e 428 SMART SM01192 139 423 2.4E-212 T 28-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CU254_RS33585 48cc2d2170011c6a0027fc3080bcbc5e 428 Gene3D G3DSA:3.30.390.10 3 127 6.7E-51 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CU254_RS33585 48cc2d2170011c6a0027fc3080bcbc5e 428 PRINTS PR00148 Enolase signature 332 346 2.2E-49 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CU254_RS33585 48cc2d2170011c6a0027fc3080bcbc5e 428 PRINTS PR00148 Enolase signature 361 378 2.2E-49 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CU254_RS33585 48cc2d2170011c6a0027fc3080bcbc5e 428 PRINTS PR00148 Enolase signature 309 320 2.2E-49 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CU254_RS33585 48cc2d2170011c6a0027fc3080bcbc5e 428 PRINTS PR00148 Enolase signature 161 174 2.2E-49 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CU254_RS33585 48cc2d2170011c6a0027fc3080bcbc5e 428 PRINTS PR00148 Enolase signature 37 51 2.2E-49 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CU254_RS33585 48cc2d2170011c6a0027fc3080bcbc5e 428 PRINTS PR00148 Enolase signature 107 123 2.2E-49 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CU254_RS33585 48cc2d2170011c6a0027fc3080bcbc5e 428 PIRSF PIRSF001400 1 422 1.4E-188 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CU254_RS33585 48cc2d2170011c6a0027fc3080bcbc5e 428 ProSitePatterns PS00164 Enolase signature. 332 345 - T 28-03-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CU254_RS33585 48cc2d2170011c6a0027fc3080bcbc5e 428 Pfam PF00113 Enolase, C-terminal TIM barrel domain 140 418 5.6E-127 T 28-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CU254_RS33585 48cc2d2170011c6a0027fc3080bcbc5e 428 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 422 1.3E-202 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CU254_RS03300 7d91a2a2d329017ee1d3aea668967f99 327 SMART SM00342 237 320 2.2E-25 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS03300 7d91a2a2d329017ee1d3aea668967f99 327 Pfam PF12833 Helix-turn-helix domain 244 321 1.8E-20 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS03300 7d91a2a2d329017ee1d3aea668967f99 327 Gene3D G3DSA:1.10.10.60 276 327 2.3E-13 T 28-03-2018 CU254_RS03300 7d91a2a2d329017ee1d3aea668967f99 327 SUPERFAMILY SSF52317 10 203 9.49E-43 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS03300 7d91a2a2d329017ee1d3aea668967f99 327 SUPERFAMILY SSF46689 274 324 1.34E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS03300 7d91a2a2d329017ee1d3aea668967f99 327 Gene3D G3DSA:1.10.10.60 238 275 5.2E-11 T 28-03-2018 CU254_RS03300 7d91a2a2d329017ee1d3aea668967f99 327 Gene3D G3DSA:3.40.50.880 5 237 8.5E-60 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS03300 7d91a2a2d329017ee1d3aea668967f99 327 SUPERFAMILY SSF46689 225 271 7.17E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS03300 7d91a2a2d329017ee1d3aea668967f99 327 Pfam PF01965 DJ-1/PfpI family 10 181 2.0E-15 T 28-03-2018 IPR002818 DJ-1/PfpI CU254_RS31885 6d3f2a0660874739c90a225fb541be84 185 TIGRFAM TIGR02464 ribofla_fusion: conserved hypothetical protein 22 181 1.4E-49 T 28-03-2018 IPR012816 NADAR CU254_RS31885 6d3f2a0660874739c90a225fb541be84 185 SUPERFAMILY SSF143990 15 183 3.4E-48 T 28-03-2018 CU254_RS31885 6d3f2a0660874739c90a225fb541be84 185 Pfam PF08719 Domain of unknown function (DUF1768) 24 181 1.5E-50 T 28-03-2018 IPR012816 NADAR CU254_RS16495 8456ae95b49b3d49fccb88e4e1f6c059 154 Pfam PF01037 Lrp/AsnC ligand binding domain 79 139 3.2E-14 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CU254_RS16495 8456ae95b49b3d49fccb88e4e1f6c059 154 Pfam PF13404 AsnC-type helix-turn-helix domain 1 42 6.0E-15 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS16495 8456ae95b49b3d49fccb88e4e1f6c059 154 Gene3D G3DSA:1.10.10.10 1 52 5.2E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS16495 8456ae95b49b3d49fccb88e4e1f6c059 154 SUPERFAMILY SSF46785 1 60 2.11E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS16495 8456ae95b49b3d49fccb88e4e1f6c059 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 3.8E-12 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS16495 8456ae95b49b3d49fccb88e4e1f6c059 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 3.8E-12 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS16495 8456ae95b49b3d49fccb88e4e1f6c059 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 3.8E-12 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS16495 8456ae95b49b3d49fccb88e4e1f6c059 154 SUPERFAMILY SSF54909 66 144 6.7E-13 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS16495 8456ae95b49b3d49fccb88e4e1f6c059 154 Gene3D G3DSA:3.30.70.920 53 138 5.9E-16 T 28-03-2018 CU254_RS16495 8456ae95b49b3d49fccb88e4e1f6c059 154 SMART SM00344 1 110 2.0E-31 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CU254_RS40185 bd0fc14c6dabbe2a085b3caf90a87106 422 TIGRFAM TIGR00414 serS: serine--tRNA ligase 2 411 3.0E-134 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CU254_RS40185 bd0fc14c6dabbe2a085b3caf90a87106 422 PRINTS PR00981 Seryl-tRNA synthetase signature 260 272 2.1E-31 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CU254_RS40185 bd0fc14c6dabbe2a085b3caf90a87106 422 PRINTS PR00981 Seryl-tRNA synthetase signature 272 285 2.1E-31 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CU254_RS40185 bd0fc14c6dabbe2a085b3caf90a87106 422 PRINTS PR00981 Seryl-tRNA synthetase signature 329 345 2.1E-31 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CU254_RS40185 bd0fc14c6dabbe2a085b3caf90a87106 422 PRINTS PR00981 Seryl-tRNA synthetase signature 347 363 2.1E-31 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CU254_RS40185 bd0fc14c6dabbe2a085b3caf90a87106 422 PRINTS PR00981 Seryl-tRNA synthetase signature 312 325 2.1E-31 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CU254_RS40185 bd0fc14c6dabbe2a085b3caf90a87106 422 SUPERFAMILY SSF55681 115 412 4.66E-87 T 28-03-2018 CU254_RS40185 bd0fc14c6dabbe2a085b3caf90a87106 422 Gene3D G3DSA:1.10.287.40 1 103 1.5E-22 T 28-03-2018 CU254_RS40185 bd0fc14c6dabbe2a085b3caf90a87106 422 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 416 39.273 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CU254_RS40185 bd0fc14c6dabbe2a085b3caf90a87106 422 SUPERFAMILY SSF46589 2 111 1.15E-25 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 CU254_RS40185 bd0fc14c6dabbe2a085b3caf90a87106 422 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 219 394 4.4E-26 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CU254_RS40185 bd0fc14c6dabbe2a085b3caf90a87106 422 Gene3D G3DSA:3.30.930.10 104 422 3.2E-82 T 28-03-2018 CU254_RS40185 bd0fc14c6dabbe2a085b3caf90a87106 422 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 106 1.1E-25 T 28-03-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 CU254_RS40185 bd0fc14c6dabbe2a085b3caf90a87106 422 PIRSF PIRSF001529 1 420 2.4E-142 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CU254_RS40075 43830b9021486f3be47380bfc1e4d9a9 318 Pfam PF13280 WYL domain 145 301 4.3E-19 T 28-03-2018 IPR026881 WYL domain CU254_RS40075 43830b9021486f3be47380bfc1e4d9a9 318 SUPERFAMILY SSF46785 5 63 3.38E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS40075 43830b9021486f3be47380bfc1e4d9a9 318 Gene3D G3DSA:1.10.10.10 2 66 2.0E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS40075 43830b9021486f3be47380bfc1e4d9a9 318 Pfam PF08279 HTH domain 7 62 3.2E-14 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 CU254_RS07800 0f0286b4cb1ce837a1f393242dd84f32 445 SUPERFAMILY SSF51556 55 369 5.53E-89 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS07800 0f0286b4cb1ce837a1f393242dd84f32 445 Pfam PF01979 Amidohydrolase family 52 417 2.6E-57 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CU254_RS07800 0f0286b4cb1ce837a1f393242dd84f32 445 Gene3D G3DSA:2.30.40.10 357 445 5.1E-11 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS07800 0f0286b4cb1ce837a1f393242dd84f32 445 Gene3D G3DSA:3.20.20.140 65 356 2.8E-60 T 28-03-2018 CU254_RS07800 0f0286b4cb1ce837a1f393242dd84f32 445 SUPERFAMILY SSF51338 369 442 1.25E-24 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS07800 0f0286b4cb1ce837a1f393242dd84f32 445 SUPERFAMILY SSF51338 2 55 1.25E-24 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS07800 0f0286b4cb1ce837a1f393242dd84f32 445 Gene3D G3DSA:2.30.40.10 1 64 3.5E-19 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS10930 ac0f45da694d28a6e87e6ce772e349b3 517 SUPERFAMILY SSF54373 294 456 4.81E-43 T 28-03-2018 CU254_RS10930 ac0f45da694d28a6e87e6ce772e349b3 517 Pfam PF00732 GMC oxidoreductase 6 300 2.0E-76 T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CU254_RS10930 ac0f45da694d28a6e87e6ce772e349b3 517 Gene3D G3DSA:3.30.560.10 359 471 4.9E-30 T 28-03-2018 CU254_RS10930 ac0f45da694d28a6e87e6ce772e349b3 517 Gene3D G3DSA:3.30.560.10 106 358 2.9E-65 T 28-03-2018 CU254_RS10930 ac0f45da694d28a6e87e6ce772e349b3 517 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 258 272 - T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CU254_RS10930 ac0f45da694d28a6e87e6ce772e349b3 517 PIRSF PIRSF000137 1 321 4.0E-90 T 28-03-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CU254_RS10930 ac0f45da694d28a6e87e6ce772e349b3 517 PIRSF PIRSF000137 323 517 1.6E-50 T 28-03-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CU254_RS10930 ac0f45da694d28a6e87e6ce772e349b3 517 Pfam PF05199 GMC oxidoreductase 371 508 1.8E-40 T 28-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 CU254_RS10930 ac0f45da694d28a6e87e6ce772e349b3 517 SUPERFAMILY SSF51905 4 292 9.59E-75 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS10930 ac0f45da694d28a6e87e6ce772e349b3 517 SUPERFAMILY SSF51905 455 516 9.59E-75 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS10930 ac0f45da694d28a6e87e6ce772e349b3 517 Gene3D G3DSA:4.10.450.10 39 105 1.8E-15 T 28-03-2018 CU254_RS34925 3226e56231e52632290007707555845f 425 Pfam PF05977 Transmembrane secretion effector 21 408 9.7E-39 T 28-03-2018 IPR010290 Transmembrane secretion effector CU254_RS34925 3226e56231e52632290007707555845f 425 SUPERFAMILY SSF103473 25 412 9.29E-37 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS34925 3226e56231e52632290007707555845f 425 Gene3D G3DSA:1.20.1250.20 222 423 3.9E-13 T 28-03-2018 CU254_RS34925 3226e56231e52632290007707555845f 425 Gene3D G3DSA:1.20.1250.20 19 216 1.2E-18 T 28-03-2018 CU254_RS25475 48424b9d38ca38df4b3597e2ced1b153 275 SUPERFAMILY SSF53335 10 262 1.49E-70 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS25475 48424b9d38ca38df4b3597e2ced1b153 275 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 11 249 1.5E-77 T 28-03-2018 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 CU254_RS25475 48424b9d38ca38df4b3597e2ced1b153 275 Gene3D G3DSA:3.40.50.150 8 255 1.0E-60 T 28-03-2018 CU254_RS25475 48424b9d38ca38df4b3597e2ced1b153 275 Pfam PF04072 Leucine carboxyl methyltransferase 14 180 1.1E-54 T 28-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CU254_RS09700 814a80f9074161555fb0eb6021f1137f 493 Pfam PF00919 Uncharacterized protein family UPF0004 6 104 3.8E-27 T 28-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 CU254_RS09700 814a80f9074161555fb0eb6021f1137f 493 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 4 448 65.334 T 28-03-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 CU254_RS09700 814a80f9074161555fb0eb6021f1137f 493 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 5 441 2.2E-144 T 28-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 CU254_RS09700 814a80f9074161555fb0eb6021f1137f 493 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 151 171 - T 28-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 CU254_RS09700 814a80f9074161555fb0eb6021f1137f 493 SMART SM00729 147 366 2.5E-55 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CU254_RS09700 814a80f9074161555fb0eb6021f1137f 493 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 5 420 2.0E-135 T 28-03-2018 CU254_RS09700 814a80f9074161555fb0eb6021f1137f 493 Pfam PF04055 Radical SAM superfamily 151 322 9.9E-29 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CU254_RS09700 814a80f9074161555fb0eb6021f1137f 493 Gene3D G3DSA:3.80.30.20 144 379 1.2E-51 T 28-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe CU254_RS09700 814a80f9074161555fb0eb6021f1137f 493 SUPERFAMILY SSF102114 132 373 2.49E-58 T 28-03-2018 CU254_RS25750 96f89e40c1796a6a69ec4c34ba621380 198 SUPERFAMILY SSF51161 6 156 8.59E-22 T 28-03-2018 IPR011004 Trimeric LpxA-like CU254_RS25750 96f89e40c1796a6a69ec4c34ba621380 198 Gene3D G3DSA:2.160.10.10 1 162 6.0E-24 T 28-03-2018 CU254_RS31620 a0db7255d278f0a627bf6c933ee56e40 491 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 8 218 9.4E-20 T 28-03-2018 CU254_RS31620 a0db7255d278f0a627bf6c933ee56e40 491 SUPERFAMILY SSF51905 1 223 2.16E-56 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS31620 a0db7255d278f0a627bf6c933ee56e40 491 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 170 195 1.2E-9 T 28-03-2018 CU254_RS31620 a0db7255d278f0a627bf6c933ee56e40 491 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 129 138 1.2E-9 T 28-03-2018 CU254_RS31620 a0db7255d278f0a627bf6c933ee56e40 491 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 1.2E-9 T 28-03-2018 CU254_RS31620 a0db7255d278f0a627bf6c933ee56e40 491 SUPERFAMILY SSF51905 264 446 1.49E-14 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS31620 a0db7255d278f0a627bf6c933ee56e40 491 Gene3D G3DSA:3.50.50.60 160 491 7.2E-51 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS31620 a0db7255d278f0a627bf6c933ee56e40 491 Gene3D G3DSA:3.50.50.60 4 159 5.6E-39 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS31385 0c2e14d4405d43dc23de8e407593f2b2 351 TIGRFAM TIGR00260 thrC: threonine synthase 8 324 8.8E-92 T 28-03-2018 IPR004450 Threonine synthase-like CU254_RS31385 0c2e14d4405d43dc23de8e407593f2b2 351 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 24 318 1.3E-73 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CU254_RS31385 0c2e14d4405d43dc23de8e407593f2b2 351 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 52 65 - T 28-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 CU254_RS31385 0c2e14d4405d43dc23de8e407593f2b2 351 Gene3D G3DSA:3.40.50.1100 146 331 4.8E-52 T 28-03-2018 CU254_RS31385 0c2e14d4405d43dc23de8e407593f2b2 351 PIRSF PIRSF038945 1 350 2.6E-166 T 28-03-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 CU254_RS31385 0c2e14d4405d43dc23de8e407593f2b2 351 SUPERFAMILY SSF53686 2 329 3.67E-102 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CU254_RS31385 0c2e14d4405d43dc23de8e407593f2b2 351 Gene3D G3DSA:3.40.50.1100 39 145 6.8E-28 T 28-03-2018 CU254_RS17135 bf26086fb2700124c42e280b29ea0d7a 666 Pfam PF01055 Glycosyl hydrolases family 31 208 660 4.7E-117 T 28-03-2018 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 CU254_RS17135 bf26086fb2700124c42e280b29ea0d7a 666 SUPERFAMILY SSF51445 217 575 3.95E-61 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS17135 bf26086fb2700124c42e280b29ea0d7a 666 Gene3D G3DSA:2.60.40.1180 597 658 6.4E-28 T 28-03-2018 CU254_RS17135 bf26086fb2700124c42e280b29ea0d7a 666 Gene3D G3DSA:2.60.40.1760 1 213 5.2E-41 T 28-03-2018 CU254_RS17135 bf26086fb2700124c42e280b29ea0d7a 666 Pfam PF13802 Galactose mutarotase-like 134 187 1.3E-7 T 28-03-2018 IPR025887 Glycoside hydrolase family 31, N-terminal domain CU254_RS17135 bf26086fb2700124c42e280b29ea0d7a 666 Gene3D G3DSA:3.20.20.80 214 596 9.6E-118 T 28-03-2018 CU254_RS17135 bf26086fb2700124c42e280b29ea0d7a 666 SUPERFAMILY SSF51011 577 658 8.63E-23 T 28-03-2018 CU254_RS17135 bf26086fb2700124c42e280b29ea0d7a 666 SUPERFAMILY SSF74650 7 214 8.16E-30 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CU254_RS37095 3fca7b88ed6da39e7a2b7d69fed17dde 278 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 66 272 5.4E-38 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CU254_RS37095 3fca7b88ed6da39e7a2b7d69fed17dde 278 SMART SM00646 150 272 2.3E-23 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CU254_RS37095 3fca7b88ed6da39e7a2b7d69fed17dde 278 Gene3D G3DSA:3.40.630.40 46 278 2.8E-49 T 28-03-2018 CU254_RS37095 3fca7b88ed6da39e7a2b7d69fed17dde 278 SUPERFAMILY SSF53187 63 275 6.91E-36 T 28-03-2018 CU254_RS22460 c7a9fbf397e0aaaabe02615756d00f6c 342 SMART SM00859 4 136 6.0E-41 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CU254_RS22460 c7a9fbf397e0aaaabe02615756d00f6c 342 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 3 336 37.252 T 28-03-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CU254_RS22460 c7a9fbf397e0aaaabe02615756d00f6c 342 Gene3D G3DSA:3.40.50.720 1 153 3.8E-43 T 28-03-2018 CU254_RS22460 c7a9fbf397e0aaaabe02615756d00f6c 342 SUPERFAMILY SSF51735 3 171 4.85E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS22460 c7a9fbf397e0aaaabe02615756d00f6c 342 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 4 128 6.6E-24 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CU254_RS22460 c7a9fbf397e0aaaabe02615756d00f6c 342 SUPERFAMILY SSF55347 146 310 2.8E-45 T 28-03-2018 CU254_RS22460 c7a9fbf397e0aaaabe02615756d00f6c 342 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 141 157 - T 28-03-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CU254_RS22460 c7a9fbf397e0aaaabe02615756d00f6c 342 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 3 342 2.7E-110 T 28-03-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CU254_RS22460 c7a9fbf397e0aaaabe02615756d00f6c 342 Gene3D G3DSA:3.30.360.10 154 310 9.3E-54 T 28-03-2018 CU254_RS22460 c7a9fbf397e0aaaabe02615756d00f6c 342 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 155 313 1.0E-23 T 28-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CU254_RS18745 b200c449cb278d5e017d2aea512004f7 1022 SUPERFAMILY SSF48452 763 895 3.28E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS18745 b200c449cb278d5e017d2aea512004f7 1022 Pfam PF03704 Bacterial transcriptional activator domain 93 233 3.2E-36 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CU254_RS18745 b200c449cb278d5e017d2aea512004f7 1022 SMART SM01043 93 233 2.1E-45 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CU254_RS18745 b200c449cb278d5e017d2aea512004f7 1022 Gene3D G3DSA:1.10.10.10 8 94 1.0E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS18745 b200c449cb278d5e017d2aea512004f7 1022 Gene3D G3DSA:1.25.40.10 95 248 3.7E-19 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS18745 b200c449cb278d5e017d2aea512004f7 1022 SUPERFAMILY SSF46894 14 86 2.27E-11 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS18745 b200c449cb278d5e017d2aea512004f7 1022 SUPERFAMILY SSF52540 245 504 4.77E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS18745 b200c449cb278d5e017d2aea512004f7 1022 Gene3D G3DSA:1.25.40.10 702 1017 1.5E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS18745 b200c449cb278d5e017d2aea512004f7 1022 SUPERFAMILY SSF81901 783 820 8.63E-5 T 28-03-2018 CU254_RS18745 b200c449cb278d5e017d2aea512004f7 1022 SUPERFAMILY SSF81901 861 963 8.63E-5 T 28-03-2018 CU254_RS18745 b200c449cb278d5e017d2aea512004f7 1022 SUPERFAMILY SSF81901 614 703 8.63E-5 T 28-03-2018 CU254_RS18745 b200c449cb278d5e017d2aea512004f7 1022 SUPERFAMILY SSF48452 88 240 4.64E-29 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS18745 b200c449cb278d5e017d2aea512004f7 1022 Pfam PF00486 Transcriptional regulatory protein, C terminal 25 73 6.7E-8 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS18745 b200c449cb278d5e017d2aea512004f7 1022 SMART SM00862 14 86 2.6E-9 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS18745 b200c449cb278d5e017d2aea512004f7 1022 Pfam PF13401 AAA domain 271 371 4.0E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS18745 b200c449cb278d5e017d2aea512004f7 1022 Gene3D G3DSA:1.25.40.10 567 701 0.18 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS18745 b200c449cb278d5e017d2aea512004f7 1022 Gene3D G3DSA:3.40.50.300 249 392 9.3E-13 T 28-03-2018 CU254_RS14990 1e21b15581672bd90d9aab71e82f66b6 209 Pfam PF01613 Flavin reductase like domain 22 158 3.7E-22 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CU254_RS14990 1e21b15581672bd90d9aab71e82f66b6 209 Gene3D G3DSA:2.30.110.10 18 206 5.2E-41 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS14990 1e21b15581672bd90d9aab71e82f66b6 209 SUPERFAMILY SSF50475 16 189 2.06E-39 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS14990 1e21b15581672bd90d9aab71e82f66b6 209 SMART SM00903 19 167 9.3E-12 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CU254_RS16435 0ecf569a4b6cb1a63bc08ea13fbe3ef4 302 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2 176 0.0065 T 28-03-2018 CU254_RS16435 0ecf569a4b6cb1a63bc08ea13fbe3ef4 302 Pfam PF01370 NAD dependent epimerase/dehydratase family 2 233 1.8E-21 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CU254_RS16435 0ecf569a4b6cb1a63bc08ea13fbe3ef4 302 SUPERFAMILY SSF51735 2 300 1.28E-51 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS16435 0ecf569a4b6cb1a63bc08ea13fbe3ef4 302 Gene3D G3DSA:3.40.50.720 1 302 4.0E-45 T 28-03-2018 CU254_RS36845 66a4c7ebd93a71c5d84aef35d1c9bd10 305 Pfam PF00149 Calcineurin-like phosphoesterase 36 220 2.4E-9 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CU254_RS36845 66a4c7ebd93a71c5d84aef35d1c9bd10 305 Gene3D G3DSA:3.60.21.10 11 272 8.8E-20 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CU254_RS36845 66a4c7ebd93a71c5d84aef35d1c9bd10 305 SUPERFAMILY SSF56300 30 275 1.14E-25 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CU254_RS38500 1a78cababd3c582932b66ed07889f0b0 168 Gene3D G3DSA:1.10.287.1060 63 164 1.6E-5 T 28-03-2018 CU254_RS38500 1a78cababd3c582932b66ed07889f0b0 168 Pfam PF00934 PE family 69 156 1.7E-4 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CU254_RS07720 698350e0b769c940ef7fc1ca20f890be 852 SMART SM00388 618 686 1.2E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS07720 698350e0b769c940ef7fc1ca20f890be 852 Pfam PF13493 Domain of unknown function (DUF4118) 389 494 1.8E-25 T 28-03-2018 IPR025201 Sensor protein KdpD, transmembrane domain CU254_RS07720 698350e0b769c940ef7fc1ca20f890be 852 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 728 833 4.1E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS07720 698350e0b769c940ef7fc1ca20f890be 852 SUPERFAMILY SSF47384 606 686 1.41E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS07720 698350e0b769c940ef7fc1ca20f890be 852 Pfam PF00582 Universal stress protein family 240 362 1.8E-6 T 28-03-2018 IPR006016 UspA GO:0006950 CU254_RS07720 698350e0b769c940ef7fc1ca20f890be 852 Pfam PF00512 His Kinase A (phospho-acceptor) domain 619 685 2.9E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS07720 698350e0b769c940ef7fc1ca20f890be 852 Gene3D G3DSA:3.40.50.620 224 367 7.0E-17 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS07720 698350e0b769c940ef7fc1ca20f890be 852 Gene3D G3DSA:3.30.565.10 690 845 2.4E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS07720 698350e0b769c940ef7fc1ca20f890be 852 Gene3D G3DSA:3.40.50.300 11 148 1.2E-22 T 28-03-2018 CU254_RS07720 698350e0b769c940ef7fc1ca20f890be 852 Gene3D G3DSA:1.20.120.620 388 487 7.3E-25 T 28-03-2018 CU254_RS07720 698350e0b769c940ef7fc1ca20f890be 852 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 11 220 1.2E-98 T 28-03-2018 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 CU254_RS07720 698350e0b769c940ef7fc1ca20f890be 852 SUPERFAMILY SSF52402 241 362 1.58E-13 T 28-03-2018 CU254_RS07720 698350e0b769c940ef7fc1ca20f890be 852 SMART SM00387 727 836 7.2E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS07720 698350e0b769c940ef7fc1ca20f890be 852 Gene3D G3DSA:1.10.287.130 602 682 6.9E-13 T 28-03-2018 CU254_RS07720 698350e0b769c940ef7fc1ca20f890be 852 SUPERFAMILY SSF55874 675 834 1.83E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS07720 698350e0b769c940ef7fc1ca20f890be 852 PRINTS PR00344 Bacterial sensor protein C-terminal signature 762 776 1.6E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS07720 698350e0b769c940ef7fc1ca20f890be 852 PRINTS PR00344 Bacterial sensor protein C-terminal signature 820 833 1.6E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS07720 698350e0b769c940ef7fc1ca20f890be 852 PRINTS PR00344 Bacterial sensor protein C-terminal signature 796 814 1.6E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS18765 16fff05e75251db4e00050a839c191bb 1329 Gene3D G3DSA:3.40.50.980 26 180 2.7E-44 T 28-03-2018 CU254_RS18765 16fff05e75251db4e00050a839c191bb 1329 SUPERFAMILY SSF47336 527 601 3.27E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS18765 16fff05e75251db4e00050a839c191bb 1329 SUPERFAMILY SSF51161 1181 1315 7.62E-16 T 28-03-2018 IPR011004 Trimeric LpxA-like CU254_RS18765 16fff05e75251db4e00050a839c191bb 1329 Gene3D G3DSA:3.40.50.980 181 331 9.6E-36 T 28-03-2018 CU254_RS18765 16fff05e75251db4e00050a839c191bb 1329 Pfam PF13193 AMP-binding enzyme C-terminal domain 430 507 4.8E-10 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS18765 16fff05e75251db4e00050a839c191bb 1329 SUPERFAMILY SSF51161 724 841 1.8E-15 T 28-03-2018 IPR011004 Trimeric LpxA-like CU254_RS18765 16fff05e75251db4e00050a839c191bb 1329 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 53 446 2.8E-126 T 28-03-2018 IPR010071 Amino acid adenylation domain CU254_RS18765 16fff05e75251db4e00050a839c191bb 1329 Gene3D G3DSA:2.160.10.10 873 1064 9.3E-10 T 28-03-2018 CU254_RS18765 16fff05e75251db4e00050a839c191bb 1329 ProSitePatterns PS00455 Putative AMP-binding domain signature. 175 186 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS18765 16fff05e75251db4e00050a839c191bb 1329 Gene3D G3DSA:2.160.10.10 705 835 5.9E-12 T 28-03-2018 CU254_RS18765 16fff05e75251db4e00050a839c191bb 1329 SUPERFAMILY SSF51161 961 1077 1.94E-13 T 28-03-2018 IPR011004 Trimeric LpxA-like CU254_RS18765 16fff05e75251db4e00050a839c191bb 1329 Gene3D G3DSA:1.10.1200.10 540 608 5.4E-19 T 28-03-2018 CU254_RS18765 16fff05e75251db4e00050a839c191bb 1329 Pfam PF00550 Phosphopantetheine attachment site 536 600 4.5E-9 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS18765 16fff05e75251db4e00050a839c191bb 1329 Pfam PF00501 AMP-binding enzyme 32 422 7.7E-94 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS18765 16fff05e75251db4e00050a839c191bb 1329 Gene3D G3DSA:2.160.10.10 1205 1328 9.8E-14 T 28-03-2018 CU254_RS18765 16fff05e75251db4e00050a839c191bb 1329 Gene3D G3DSA:2.30.38.10 332 412 1.8E-25 T 28-03-2018 CU254_RS18765 16fff05e75251db4e00050a839c191bb 1329 ProSitePatterns PS00012 Phosphopantetheine attachment site. 559 574 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CU254_RS18765 16fff05e75251db4e00050a839c191bb 1329 TIGRFAM TIGR02353 NRPS_term_dom: non-ribosomal peptide synthetase terminal domain of unknown function 663 1311 1.9E-168 T 28-03-2018 IPR012728 Non-ribosomal peptide synthetase, C-terminal CU254_RS18765 16fff05e75251db4e00050a839c191bb 1329 Gene3D G3DSA:3.30.300.30 418 539 2.1E-32 T 28-03-2018 CU254_RS18765 16fff05e75251db4e00050a839c191bb 1329 SUPERFAMILY SSF56801 26 546 7.72E-147 T 28-03-2018 CU254_RS16835 a0e5dabdbe8b6fac9bbf763c90fe423d 277 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 268 9.6E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS16835 a0e5dabdbe8b6fac9bbf763c90fe423d 277 SUPERFAMILY SSF161098 78 256 1.7E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS16835 a0e5dabdbe8b6fac9bbf763c90fe423d 277 Gene3D G3DSA:1.10.3720.10 4 265 1.1E-29 T 28-03-2018 CU254_RS24185 7bab4ec51fdd096b25e3787144536345 393 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 223 373 1.4E-11 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS24185 7bab4ec51fdd096b25e3787144536345 393 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 117 199 3.9E-21 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CU254_RS24185 7bab4ec51fdd096b25e3787144536345 393 Gene3D G3DSA:2.40.110.10 113 210 1.6E-32 T 28-03-2018 CU254_RS24185 7bab4ec51fdd096b25e3787144536345 393 SUPERFAMILY SSF56645 6 235 2.36E-57 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS24185 7bab4ec51fdd096b25e3787144536345 393 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 5 111 8.4E-10 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS24185 7bab4ec51fdd096b25e3787144536345 393 Gene3D G3DSA:1.20.140.10 211 384 2.7E-26 T 28-03-2018 CU254_RS24185 7bab4ec51fdd096b25e3787144536345 393 Gene3D G3DSA:1.10.540.10 2 112 7.6E-13 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS24185 7bab4ec51fdd096b25e3787144536345 393 SUPERFAMILY SSF47203 223 375 2.66E-10 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS40235 9264122adda9a8ff22c07d9efdb3abfc 165 Pfam PF08281 Sigma-70, region 4 99 152 5.1E-15 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS40235 9264122adda9a8ff22c07d9efdb3abfc 165 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 6 153 2.7E-23 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS40235 9264122adda9a8ff22c07d9efdb3abfc 165 SUPERFAMILY SSF88659 91 153 2.18E-15 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS40235 9264122adda9a8ff22c07d9efdb3abfc 165 Gene3D G3DSA:1.10.10.10 76 157 2.5E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS40235 9264122adda9a8ff22c07d9efdb3abfc 165 Gene3D G3DSA:1.10.1740.10 2 75 1.0E-12 T 28-03-2018 CU254_RS40235 9264122adda9a8ff22c07d9efdb3abfc 165 SUPERFAMILY SSF88946 4 72 3.92E-12 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS40235 9264122adda9a8ff22c07d9efdb3abfc 165 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 4 155 2.6E-52 T 28-03-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 CU254_RS40235 9264122adda9a8ff22c07d9efdb3abfc 165 Pfam PF04542 Sigma-70 region 2 11 73 9.8E-9 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS35270 eb384973aa433fb6b032a817f39d05e0 143 Gene3D G3DSA:3.30.450.30 9 136 5.9E-44 T 28-03-2018 CU254_RS35270 eb384973aa433fb6b032a817f39d05e0 143 Pfam PF03259 Roadblock/LC7 domain 15 104 5.5E-23 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain CU254_RS35270 eb384973aa433fb6b032a817f39d05e0 143 SMART SM00960 14 104 1.2E-31 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain CU254_RS35270 eb384973aa433fb6b032a817f39d05e0 143 SUPERFAMILY SSF103196 9 131 3.84E-34 T 28-03-2018 CU254_RS26655 441030fe850658e4309fef6b2ccb3600 321 Gene3D G3DSA:3.40.50.720 154 290 9.6E-29 T 28-03-2018 CU254_RS26655 441030fe850658e4309fef6b2ccb3600 321 SMART SM00829 13 319 2.3E-12 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CU254_RS26655 441030fe850658e4309fef6b2ccb3600 321 Gene3D G3DSA:3.90.180.10 1 153 6.0E-31 T 28-03-2018 CU254_RS26655 441030fe850658e4309fef6b2ccb3600 321 SUPERFAMILY SSF51735 128 289 1.12E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS26655 441030fe850658e4309fef6b2ccb3600 321 Pfam PF00107 Zinc-binding dehydrogenase 167 282 1.3E-19 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CU254_RS26655 441030fe850658e4309fef6b2ccb3600 321 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 31 123 4.0E-5 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CU254_RS26655 441030fe850658e4309fef6b2ccb3600 321 SUPERFAMILY SSF50129 12 156 1.37E-29 T 28-03-2018 IPR011032 GroES-like CU254_RS36015 f47b455ac98688a6e3072a24e180175c 477 Pfam PF03062 MBOAT, membrane-bound O-acyltransferase family 151 347 1.2E-31 T 28-03-2018 IPR004299 Membrane bound O-acyl transferase, MBOAT CU254_RS36015 f47b455ac98688a6e3072a24e180175c 477 PIRSF PIRSF016636 1 477 5.8E-144 T 28-03-2018 IPR024194 Alginate O-acetyltransferase AlgI/D-alanyl transfer protein DltB CU254_RS36015 f47b455ac98688a6e3072a24e180175c 477 PIRSF PIRSF500217 1 477 7.5E-147 T 28-03-2018 IPR028362 Alginate O-acetyltransferase AlgI GO:0042121 CU254_RS36470 71f36e65a3c6d87e88dbeba8782b72fe 382 Pfam PF07690 Major Facilitator Superfamily 15 315 7.1E-18 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS36470 71f36e65a3c6d87e88dbeba8782b72fe 382 SUPERFAMILY SSF103473 7 374 1.96E-37 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS36470 71f36e65a3c6d87e88dbeba8782b72fe 382 Gene3D G3DSA:1.20.1250.20 193 374 1.2E-15 T 28-03-2018 CU254_RS36470 71f36e65a3c6d87e88dbeba8782b72fe 382 Gene3D G3DSA:1.20.1250.20 4 184 1.6E-14 T 28-03-2018 CU254_RS18755 5f324f7aa21f54cfed55d014a6d5ab47 677 Pfam PF05506 Domain of unknown function (DUF756) 591 661 1.4E-8 T 28-03-2018 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 CU254_RS18755 5f324f7aa21f54cfed55d014a6d5ab47 677 Pfam PF05506 Domain of unknown function (DUF756) 495 576 4.6E-21 T 28-03-2018 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 CU254_RS18755 5f324f7aa21f54cfed55d014a6d5ab47 677 Gene3D G3DSA:3.40.720.10 110 432 2.5E-27 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CU254_RS18755 5f324f7aa21f54cfed55d014a6d5ab47 677 TIGRFAM TIGR03396 PC_PLC: phospholipase C, phosphocholine-specific 5 675 5.5E-259 T 28-03-2018 IPR017767 Bacterial phospholipase C, phosphocholine-specific GO:0034480 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 CU254_RS18755 5f324f7aa21f54cfed55d014a6d5ab47 677 SUPERFAMILY SSF53649 142 432 1.79E-6 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CU254_RS18755 5f324f7aa21f54cfed55d014a6d5ab47 677 Pfam PF04185 Phosphoesterase family 44 427 1.8E-118 T 28-03-2018 IPR007312 Phosphoesterase GO:0016788 CU254_RS02685 4211af3d6ebbc346a7c1f84a7cf6b9f1 396 SUPERFAMILY SSF103473 14 388 5.1E-62 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS02685 4211af3d6ebbc346a7c1f84a7cf6b9f1 396 Gene3D G3DSA:1.20.1250.20 199 395 1.9E-23 T 28-03-2018 CU254_RS02685 4211af3d6ebbc346a7c1f84a7cf6b9f1 396 Gene3D G3DSA:1.20.1250.20 10 191 4.1E-27 T 28-03-2018 CU254_RS02685 4211af3d6ebbc346a7c1f84a7cf6b9f1 396 Pfam PF07690 Major Facilitator Superfamily 15 191 6.3E-31 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS02685 4211af3d6ebbc346a7c1f84a7cf6b9f1 396 Pfam PF07690 Major Facilitator Superfamily 212 385 3.1E-13 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS01725 7e565858b613830b20126486af8ee89c 277 Pfam PF02357 Transcription termination factor nusG 88 190 8.4E-26 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CU254_RS01725 7e565858b613830b20126486af8ee89c 277 SUPERFAMILY SSF50104 221 277 4.71E-17 T 28-03-2018 IPR008991 Translation protein SH3-like domain CU254_RS01725 7e565858b613830b20126486af8ee89c 277 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 86 277 24.082 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CU254_RS01725 7e565858b613830b20126486af8ee89c 277 PRINTS PR00338 Transcription termination factor NUSG signature 141 153 9.8E-20 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CU254_RS01725 7e565858b613830b20126486af8ee89c 277 PRINTS PR00338 Transcription termination factor NUSG signature 253 269 9.8E-20 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CU254_RS01725 7e565858b613830b20126486af8ee89c 277 PRINTS PR00338 Transcription termination factor NUSG signature 235 250 9.8E-20 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CU254_RS01725 7e565858b613830b20126486af8ee89c 277 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 89 277 5.4E-64 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CU254_RS01725 7e565858b613830b20126486af8ee89c 277 SUPERFAMILY SSF82679 88 191 1.44E-36 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CU254_RS01725 7e565858b613830b20126486af8ee89c 277 ProSitePatterns PS01014 Transcription termination factor nusG signature. 260 269 - T 28-03-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site CU254_RS01725 7e565858b613830b20126486af8ee89c 277 SMART SM00738 86 194 8.7E-51 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CU254_RS01725 7e565858b613830b20126486af8ee89c 277 Gene3D G3DSA:3.30.70.940 87 197 4.2E-38 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CU254_RS01725 7e565858b613830b20126486af8ee89c 277 Gene3D G3DSA:2.30.30.30 218 277 2.8E-19 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 CU254_RS01725 7e565858b613830b20126486af8ee89c 277 SMART SM00739 223 250 0.0059 T 28-03-2018 IPR005824 KOW CU254_RS23175 2f9943919068a492ed09d00df2f05db9 498 Gene3D G3DSA:3.40.605.10 5 261 4.8E-82 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CU254_RS23175 2f9943919068a492ed09d00df2f05db9 498 Gene3D G3DSA:3.40.309.10 262 443 2.0E-59 T 28-03-2018 CU254_RS23175 2f9943919068a492ed09d00df2f05db9 498 PIRSF PIRSF036492 28 498 1.4E-94 T 28-03-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0004030|GO:0006081|GO:0055114 CU254_RS23175 2f9943919068a492ed09d00df2f05db9 498 Pfam PF00171 Aldehyde dehydrogenase family 12 463 2.4E-130 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CU254_RS23175 2f9943919068a492ed09d00df2f05db9 498 SUPERFAMILY SSF53720 12 468 1.96E-136 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CU254_RS23175 2f9943919068a492ed09d00df2f05db9 498 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 242 249 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CU254_RS23175 2f9943919068a492ed09d00df2f05db9 498 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 270 281 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CU254_RS08730 77e095e03dd683710597ea12a4ca032c 311 Pfam PF00296 Luciferase-like monooxygenase 8 251 5.3E-52 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS08730 77e095e03dd683710597ea12a4ca032c 311 Gene3D G3DSA:3.20.20.30 2 311 2.8E-75 T 28-03-2018 CU254_RS08730 77e095e03dd683710597ea12a4ca032c 311 TIGRFAM TIGR03560 F420_Rv1855c: probable F420-dependent oxidoreductase, Rv1855c family 2 231 2.6E-95 T 28-03-2018 IPR019952 F420-dependent oxidoreductase-predicted, Rv1855c CU254_RS08730 77e095e03dd683710597ea12a4ca032c 311 SUPERFAMILY SSF51679 4 310 1.31E-72 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS06235 a10540004765d3af5bc8caeb6be4d8b1 408 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 15 385 1.6E-91 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CU254_RS06235 a10540004765d3af5bc8caeb6be4d8b1 408 Pfam PF07687 Peptidase dimerisation domain 197 289 7.4E-14 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CU254_RS06235 a10540004765d3af5bc8caeb6be4d8b1 408 SUPERFAMILY SSF55031 194 305 2.39E-30 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CU254_RS06235 a10540004765d3af5bc8caeb6be4d8b1 408 Pfam PF01546 Peptidase family M20/M25/M40 78 395 2.0E-30 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CU254_RS06235 a10540004765d3af5bc8caeb6be4d8b1 408 SUPERFAMILY SSF53187 5 206 6.91E-69 T 28-03-2018 CU254_RS06235 a10540004765d3af5bc8caeb6be4d8b1 408 SUPERFAMILY SSF53187 307 399 6.91E-69 T 28-03-2018 CU254_RS06235 a10540004765d3af5bc8caeb6be4d8b1 408 Gene3D G3DSA:3.40.630.10 259 405 3.0E-19 T 28-03-2018 CU254_RS06235 a10540004765d3af5bc8caeb6be4d8b1 408 Gene3D G3DSA:3.40.630.10 2 251 8.5E-38 T 28-03-2018 CU254_RS06235 a10540004765d3af5bc8caeb6be4d8b1 408 PIRSF PIRSF005962 1 402 1.9E-101 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CU254_RS10425 2cfaecfe8be167433e7eec7c24a1826c 286 Pfam PF01575 MaoC like domain 164 264 1.6E-28 T 28-03-2018 IPR002539 MaoC-like domain CU254_RS10425 2cfaecfe8be167433e7eec7c24a1826c 286 SUPERFAMILY SSF54637 161 279 5.52E-30 T 28-03-2018 IPR029069 HotDog domain CU254_RS10425 2cfaecfe8be167433e7eec7c24a1826c 286 Gene3D G3DSA:3.10.129.10 162 284 3.0E-26 T 28-03-2018 CU254_RS10425 2cfaecfe8be167433e7eec7c24a1826c 286 Pfam PF13452 N-terminal half of MaoC dehydratase 8 138 7.6E-20 T 28-03-2018 CU254_RS10425 2cfaecfe8be167433e7eec7c24a1826c 286 Gene3D G3DSA:3.10.129.10 13 161 3.6E-45 T 28-03-2018 CU254_RS10425 2cfaecfe8be167433e7eec7c24a1826c 286 SUPERFAMILY SSF54637 8 160 4.29E-47 T 28-03-2018 IPR029069 HotDog domain CU254_RS32785 62bd3bfcebafdadab20da32848e8903e 421 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 7 407 23.335 T 28-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 CU254_RS32785 62bd3bfcebafdadab20da32848e8903e 421 Pfam PF13742 OB-fold nucleic acid binding domain 14 108 1.0E-13 T 28-03-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 CU254_RS32785 62bd3bfcebafdadab20da32848e8903e 421 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 15 405 1.0E-110 T 28-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 CU254_RS32785 62bd3bfcebafdadab20da32848e8903e 421 Gene3D G3DSA:3.90.226.10 150 244 8.2E-5 T 28-03-2018 CU254_RS32785 62bd3bfcebafdadab20da32848e8903e 421 Pfam PF02601 Exonuclease VII, large subunit 325 404 6.6E-8 T 28-03-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 CU254_RS32785 62bd3bfcebafdadab20da32848e8903e 421 Pfam PF02601 Exonuclease VII, large subunit 131 330 4.0E-57 T 28-03-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 CU254_RS32785 62bd3bfcebafdadab20da32848e8903e 421 Gene3D G3DSA:2.40.50.140 18 125 1.6E-4 T 28-03-2018 CU254_RS27520 e5ae82b9ae6c42c1ef2b233fd0c45862 165 Gene3D G3DSA:2.160.10.10 80 164 4.6E-6 T 28-03-2018 CU254_RS27520 e5ae82b9ae6c42c1ef2b233fd0c45862 165 Gene3D G3DSA:2.160.20.50 2 79 5.9E-5 T 28-03-2018 CU254_RS27520 e5ae82b9ae6c42c1ef2b233fd0c45862 165 SUPERFAMILY SSF51161 24 156 6.93E-11 T 28-03-2018 IPR011004 Trimeric LpxA-like CU254_RS42505 6cc80f65004d738f2665752fd3968f3d 80 Pfam PF04149 Domain of unknown function (DUF397) 16 71 4.0E-15 T 28-03-2018 IPR007278 Domain of unknown function DUF397 CU254_RS16090 7f907e7f2a665d24cfee8ab709498f82 606 Pfam PF00501 AMP-binding enzyme 22 414 2.0E-91 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS16090 7f907e7f2a665d24cfee8ab709498f82 606 SUPERFAMILY SSF56801 11 532 4.06E-149 T 28-03-2018 CU254_RS16090 7f907e7f2a665d24cfee8ab709498f82 606 Gene3D G3DSA:3.30.300.30 409 522 1.0E-39 T 28-03-2018 CU254_RS16090 7f907e7f2a665d24cfee8ab709498f82 606 SMART SM00823 Phosphopantetheine attachment site 519 589 3.8E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS16090 7f907e7f2a665d24cfee8ab709498f82 606 Pfam PF13193 AMP-binding enzyme C-terminal domain 422 493 2.7E-10 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS16090 7f907e7f2a665d24cfee8ab709498f82 606 SUPERFAMILY SSF47336 512 585 2.36E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS16090 7f907e7f2a665d24cfee8ab709498f82 606 Gene3D G3DSA:3.40.50.980 164 315 2.2E-36 T 28-03-2018 CU254_RS16090 7f907e7f2a665d24cfee8ab709498f82 606 ProSitePatterns PS00012 Phosphopantetheine attachment site. 544 559 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CU254_RS16090 7f907e7f2a665d24cfee8ab709498f82 606 Gene3D G3DSA:1.10.1200.10 523 596 9.9E-24 T 28-03-2018 CU254_RS16090 7f907e7f2a665d24cfee8ab709498f82 606 Pfam PF00550 Phosphopantetheine attachment site 521 584 1.2E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS16090 7f907e7f2a665d24cfee8ab709498f82 606 Gene3D G3DSA:2.30.38.10 324 404 8.7E-24 T 28-03-2018 CU254_RS16090 7f907e7f2a665d24cfee8ab709498f82 606 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 44 438 1.5E-124 T 28-03-2018 IPR010071 Amino acid adenylation domain CU254_RS16090 7f907e7f2a665d24cfee8ab709498f82 606 Gene3D G3DSA:3.40.50.980 15 163 1.0E-44 T 28-03-2018 CU254_RS05120 932b68fe7b10f79a6db75757afcfcbac 184 Gene3D G3DSA:3.40.390.10 36 168 1.1E-21 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CU254_RS05120 932b68fe7b10f79a6db75757afcfcbac 184 Pfam PF02031 Streptomyces extracellular neutral proteinase (M7) family 36 168 6.4E-65 T 28-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 CU254_RS05120 932b68fe7b10f79a6db75757afcfcbac 184 SUPERFAMILY SSF55486 38 165 2.02E-28 T 28-03-2018 CU254_RS05120 932b68fe7b10f79a6db75757afcfcbac 184 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 101 125 1.1E-51 T 28-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 CU254_RS05120 932b68fe7b10f79a6db75757afcfcbac 184 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 153 167 1.1E-51 T 28-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 CU254_RS05120 932b68fe7b10f79a6db75757afcfcbac 184 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 126 150 1.1E-51 T 28-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 CU254_RS05120 932b68fe7b10f79a6db75757afcfcbac 184 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 43 69 1.1E-51 T 28-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 CU254_RS05120 932b68fe7b10f79a6db75757afcfcbac 184 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 76 100 1.1E-51 T 28-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 CU254_RS05120 932b68fe7b10f79a6db75757afcfcbac 184 PIRSF PIRSF016573 1 34 34.0 T 28-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 CU254_RS05120 932b68fe7b10f79a6db75757afcfcbac 184 PIRSF PIRSF016573 23 179 7.3E-71 T 28-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 CU254_RS05120 932b68fe7b10f79a6db75757afcfcbac 184 ProDom PD016028 PROTEASE METALLOPROTEASE EXTRACELLULAR NEUTRAL SMALL METAL-BINDING ZINC HYDROLASE SNAPALYSIN ZYMOGEN 46 168 4.0E-46 T 28-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 CU254_RS15720 d70ef72357c3b2024932cbb01674d8f1 292 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 188 284 1.9E-19 T 28-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal CU254_RS15720 d70ef72357c3b2024932cbb01674d8f1 292 Gene3D G3DSA:3.30.465.10 66 177 2.2E-24 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CU254_RS15720 d70ef72357c3b2024932cbb01674d8f1 292 SMART SM01092 184 286 1.5E-23 T 28-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal CU254_RS15720 d70ef72357c3b2024932cbb01674d8f1 292 SUPERFAMILY SSF55447 185 289 2.09E-24 T 28-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal CU254_RS15720 d70ef72357c3b2024932cbb01674d8f1 292 Gene3D G3DSA:3.30.43.10 1 57 1.9E-16 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CU254_RS15720 d70ef72357c3b2024932cbb01674d8f1 292 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 5 176 2.7E-34 T 28-03-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 CU254_RS15720 d70ef72357c3b2024932cbb01674d8f1 292 SUPERFAMILY SSF56176 1 177 4.25E-39 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CU254_RS15720 d70ef72357c3b2024932cbb01674d8f1 292 Gene3D G3DSA:3.30.390.50 181 292 3.4E-27 T 28-03-2018 CU254_RS25675 3ccb3aea5f7433af8cf6f21c353eead3 149 Gene3D G3DSA:3.30.530.20 2 145 1.5E-19 T 28-03-2018 IPR023393 START-like domain CU254_RS25675 3ccb3aea5f7433af8cf6f21c353eead3 149 SUPERFAMILY SSF55961 3 144 4.3E-26 T 28-03-2018 CU254_RS25675 3ccb3aea5f7433af8cf6f21c353eead3 149 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 6 132 2.1E-12 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase CU254_RS10905 e086264a5cfab95f2e1ba01dd180da41 218 Gene3D G3DSA:3.40.50.720 1 146 2.0E-23 T 28-03-2018 CU254_RS10905 e086264a5cfab95f2e1ba01dd180da41 218 Pfam PF02254 TrkA-N domain 3 118 3.7E-26 T 28-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CU254_RS10905 e086264a5cfab95f2e1ba01dd180da41 218 SUPERFAMILY SSF51735 1 145 2.46E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS10905 e086264a5cfab95f2e1ba01dd180da41 218 SUPERFAMILY SSF116726 133 216 3.66E-15 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CU254_RS10905 e086264a5cfab95f2e1ba01dd180da41 218 Pfam PF02080 TrkA-C domain 149 213 7.3E-15 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CU254_RS10905 e086264a5cfab95f2e1ba01dd180da41 218 Gene3D G3DSA:3.30.70.1450 147 218 9.0E-18 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CU254_RS10905 e086264a5cfab95f2e1ba01dd180da41 218 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 3.5E-10 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CU254_RS10905 e086264a5cfab95f2e1ba01dd180da41 218 PRINTS PR00335 TrkA potassium uptake protein signature 59 69 3.5E-10 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CU254_RS10905 e086264a5cfab95f2e1ba01dd180da41 218 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 3.5E-10 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CU254_RS10905 e086264a5cfab95f2e1ba01dd180da41 218 PRINTS PR00335 TrkA potassium uptake protein signature 48 58 3.5E-10 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CU254_RS10905 e086264a5cfab95f2e1ba01dd180da41 218 PRINTS PR00335 TrkA potassium uptake protein signature 72 86 3.5E-10 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CU254_RS07190 52d24ddda422bb7415cc580eaf48a75d 310 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 102 112 - T 28-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site CU254_RS07190 52d24ddda422bb7415cc580eaf48a75d 310 SUPERFAMILY SSF52743 35 288 1.44E-60 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS07190 52d24ddda422bb7415cc580eaf48a75d 310 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 65 76 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CU254_RS07190 52d24ddda422bb7415cc580eaf48a75d 310 Pfam PF00082 Subtilase family 60 288 2.0E-32 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS07190 52d24ddda422bb7415cc580eaf48a75d 310 PRINTS PR00723 Subtilisin serine protease family (S8) signature 60 79 1.1E-18 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CU254_RS07190 52d24ddda422bb7415cc580eaf48a75d 310 PRINTS PR00723 Subtilisin serine protease family (S8) signature 98 111 1.1E-18 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CU254_RS07190 52d24ddda422bb7415cc580eaf48a75d 310 PRINTS PR00723 Subtilisin serine protease family (S8) signature 249 265 1.1E-18 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CU254_RS07190 52d24ddda422bb7415cc580eaf48a75d 310 Gene3D G3DSA:3.40.50.200 32 306 2.2E-66 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS18050 44c6b4deadbf70025b51b6def8e9ce74 226 SMART SM00862 151 223 9.0E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS18050 44c6b4deadbf70025b51b6def8e9ce74 226 Gene3D G3DSA:1.10.10.10 120 225 5.4E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS18050 44c6b4deadbf70025b51b6def8e9ce74 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 223 1.0E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS18050 44c6b4deadbf70025b51b6def8e9ce74 226 SMART SM00448 6 114 9.9E-36 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS18050 44c6b4deadbf70025b51b6def8e9ce74 226 SUPERFAMILY SSF52172 6 189 1.99E-36 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS18050 44c6b4deadbf70025b51b6def8e9ce74 226 Pfam PF00072 Response regulator receiver domain 8 114 3.4E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS18050 44c6b4deadbf70025b51b6def8e9ce74 226 Gene3D G3DSA:3.40.50.2300 2 119 9.0E-35 T 28-03-2018 CU254_RS05620 2c9921c13780a987833e910859db4e77 666 Pfam PF09375 Imelysin 439 631 4.1E-9 T 28-03-2018 IPR018976 Peptidase M75, Imelysin CU254_RS05620 2c9921c13780a987833e910859db4e77 666 Pfam PF13473 Cupredoxin-like domain 306 397 2.9E-6 T 28-03-2018 IPR028096 EfeO-type cupredoxin-like domain CU254_RS05620 2c9921c13780a987833e910859db4e77 666 Pfam PF03239 Iron permease FTR1 family 1 254 5.2E-36 T 28-03-2018 IPR004923 Iron permease FTR1/Fip1/EfeU GO:0005381|GO:0006827|GO:0016020|GO:0033573 CU254_RS27530 3c6bc13926de44941490c9d7e25cc079 322 SUPERFAMILY SSF50182 145 202 8.5E-12 T 28-03-2018 IPR010920 LSM domain CU254_RS27530 3c6bc13926de44941490c9d7e25cc079 322 Gene3D G3DSA:3.30.70.100 210 308 4.9E-14 T 28-03-2018 CU254_RS27530 3c6bc13926de44941490c9d7e25cc079 322 SUPERFAMILY SSF82861 89 144 6.15E-12 T 28-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 CU254_RS27530 3c6bc13926de44941490c9d7e25cc079 322 Pfam PF00924 Mechanosensitive ion channel 104 301 5.4E-37 T 28-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 CU254_RS27530 3c6bc13926de44941490c9d7e25cc079 322 SUPERFAMILY SSF82689 210 304 1.29E-12 T 28-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 CU254_RS27530 3c6bc13926de44941490c9d7e25cc079 322 Gene3D G3DSA:2.30.30.60 161 209 7.3E-10 T 28-03-2018 CU254_RS31145 fae4567975b1091aad7dc28780c65ebc 565 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 45 465 1.3E-72 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CU254_RS31145 fae4567975b1091aad7dc28780c65ebc 565 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 160 185 - T 28-03-2018 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 CU254_RS31145 fae4567975b1091aad7dc28780c65ebc 565 Pfam PF00474 Sodium:solute symporter family 45 465 1.6E-45 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CU254_RS38280 a5e8c2a7c0ea95fd564faca70d23de98 161 Gene3D G3DSA:1.10.10.10 3 143 1.3E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS38280 a5e8c2a7c0ea95fd564faca70d23de98 161 SMART SM00347 29 129 8.5E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS38280 a5e8c2a7c0ea95fd564faca70d23de98 161 Pfam PF12802 MarR family 35 93 4.7E-13 T 28-03-2018 CU254_RS38280 a5e8c2a7c0ea95fd564faca70d23de98 161 SUPERFAMILY SSF46785 17 144 3.81E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS04675 861a798c7a77ca00f37b52588f567060 120 SUPERFAMILY SSF54909 1 113 8.04E-29 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS04675 861a798c7a77ca00f37b52588f567060 120 Pfam PF03795 YCII-related domain 1 111 3.7E-18 T 28-03-2018 IPR005545 YCII-related CU254_RS04675 861a798c7a77ca00f37b52588f567060 120 Gene3D G3DSA:3.30.70.1060 1 115 6.3E-35 T 28-03-2018 CU254_RS07610 3256cb0fb360e2853347cafd303baef3 284 SMART SM01092 180 281 8.5E-29 T 28-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal CU254_RS07610 3256cb0fb360e2853347cafd303baef3 284 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 5 174 4.5E-50 T 28-03-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 CU254_RS07610 3256cb0fb360e2853347cafd303baef3 284 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 181 280 1.1E-21 T 28-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal CU254_RS07610 3256cb0fb360e2853347cafd303baef3 284 Gene3D G3DSA:3.30.390.50 177 284 1.6E-25 T 28-03-2018 CU254_RS07610 3256cb0fb360e2853347cafd303baef3 284 SUPERFAMILY SSF55447 177 282 1.57E-28 T 28-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal CU254_RS07610 3256cb0fb360e2853347cafd303baef3 284 SUPERFAMILY SSF56176 2 174 8.0E-56 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CU254_RS07610 3256cb0fb360e2853347cafd303baef3 284 Gene3D G3DSA:3.30.465.10 60 174 8.2E-33 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CU254_RS07610 3256cb0fb360e2853347cafd303baef3 284 Gene3D G3DSA:3.30.43.10 1 54 1.1E-19 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CU254_RS35645 b0225e60a4a420720ccaac0cdc621d5b 250 SUPERFAMILY SSF109854 8 138 2.29E-6 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CU254_RS35645 b0225e60a4a420720ccaac0cdc621d5b 250 Gene3D G3DSA:1.20.120.450 9 248 0.53 T 28-03-2018 CU254_RS33160 daae3cca9a90892223af35ed04a89df3 827 Gene3D G3DSA:2.60.34.10 480 636 9.9E-20 T 28-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 CU254_RS33160 daae3cca9a90892223af35ed04a89df3 827 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 9 16 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CU254_RS33160 daae3cca9a90892223af35ed04a89df3 827 Pfam PF00012 Hsp70 protein 478 643 1.1E-4 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CU254_RS33160 daae3cca9a90892223af35ed04a89df3 827 Pfam PF00012 Hsp70 protein 7 364 1.2E-62 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CU254_RS33160 daae3cca9a90892223af35ed04a89df3 827 Gene3D G3DSA:3.30.420.40 6 174 1.5E-34 T 28-03-2018 CU254_RS33160 daae3cca9a90892223af35ed04a89df3 827 PRINTS PR00301 70kDa heat shock protein signature 177 187 7.1E-16 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CU254_RS33160 daae3cca9a90892223af35ed04a89df3 827 PRINTS PR00301 70kDa heat shock protein signature 348 368 7.1E-16 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CU254_RS33160 daae3cca9a90892223af35ed04a89df3 827 PRINTS PR00301 70kDa heat shock protein signature 5 18 7.1E-16 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CU254_RS33160 daae3cca9a90892223af35ed04a89df3 827 PRINTS PR00301 70kDa heat shock protein signature 116 136 7.1E-16 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CU254_RS33160 daae3cca9a90892223af35ed04a89df3 827 PRINTS PR00301 70kDa heat shock protein signature 314 330 7.1E-16 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CU254_RS33160 daae3cca9a90892223af35ed04a89df3 827 SUPERFAMILY SSF100920 487 598 4.19E-10 T 28-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 CU254_RS33160 daae3cca9a90892223af35ed04a89df3 827 SUPERFAMILY SSF53067 166 363 6.48E-39 T 28-03-2018 CU254_RS33160 daae3cca9a90892223af35ed04a89df3 827 Gene3D G3DSA:3.30.420.40 175 338 1.2E-29 T 28-03-2018 CU254_RS33160 daae3cca9a90892223af35ed04a89df3 827 SUPERFAMILY SSF53067 7 160 9.32E-30 T 28-03-2018 CU254_RS12250 c5903f35e3ccb7be7532ac5e4209b2c0 293 SUPERFAMILY SSF56281 2 289 9.1E-42 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS12250 c5903f35e3ccb7be7532ac5e4209b2c0 293 Gene3D G3DSA:3.60.15.10 1 293 2.0E-40 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS12250 c5903f35e3ccb7be7532ac5e4209b2c0 293 Pfam PF12706 Beta-lactamase superfamily domain 32 256 9.7E-17 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS22505 d96c5fa09d94e40e2a55abae00159f06 201 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 24 92 1.9E-28 T 28-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CU254_RS22505 d96c5fa09d94e40e2a55abae00159f06 201 SUPERFAMILY SSF54364 22 95 1.57E-27 T 28-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CU254_RS22505 d96c5fa09d94e40e2a55abae00159f06 201 Gene3D G3DSA:3.10.20.80 19 95 2.7E-30 T 28-03-2018 CU254_RS22505 d96c5fa09d94e40e2a55abae00159f06 201 SUPERFAMILY SSF55200 102 186 2.09E-30 T 28-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 CU254_RS22505 d96c5fa09d94e40e2a55abae00159f06 201 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 18 187 29.051 T 28-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CU254_RS22505 d96c5fa09d94e40e2a55abae00159f06 201 ProSitePatterns PS00938 Initiation factor 3 signature. 75 88 - T 28-03-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 CU254_RS22505 d96c5fa09d94e40e2a55abae00159f06 201 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 101 184 9.8E-34 T 28-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 CU254_RS22505 d96c5fa09d94e40e2a55abae00159f06 201 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 24 186 1.5E-59 T 28-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CU254_RS22505 d96c5fa09d94e40e2a55abae00159f06 201 Gene3D G3DSA:3.30.110.10 96 195 1.5E-32 T 28-03-2018 CU254_RS31745 aebab69ab2889f786ef3cb8f2631c5b0 516 Gene3D G3DSA:3.30.465.10 150 293 7.5E-27 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CU254_RS31745 aebab69ab2889f786ef3cb8f2631c5b0 516 Pfam PF02913 FAD linked oxidases, C-terminal domain 271 512 4.9E-41 T 28-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CU254_RS31745 aebab69ab2889f786ef3cb8f2631c5b0 516 Gene3D G3DSA:3.30.43.10 9 149 8.4E-18 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CU254_RS31745 aebab69ab2889f786ef3cb8f2631c5b0 516 SUPERFAMILY SSF55103 277 515 2.13E-34 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CU254_RS31745 aebab69ab2889f786ef3cb8f2631c5b0 516 Gene3D G3DSA:1.10.45.10 476 514 2.4E-7 T 28-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CU254_RS31745 aebab69ab2889f786ef3cb8f2631c5b0 516 Pfam PF01565 FAD binding domain 95 230 1.0E-34 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CU254_RS31745 aebab69ab2889f786ef3cb8f2631c5b0 516 SUPERFAMILY SSF56176 63 271 4.53E-44 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CU254_RS29850 b9cf4f7f120fd5d715f9896ebe95f9eb 657 Pfam PF00931 NB-ARC domain 47 237 2.2E-12 T 28-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 CU254_RS29850 b9cf4f7f120fd5d715f9896ebe95f9eb 657 Gene3D G3DSA:1.25.40.10 549 656 1.4E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS29850 b9cf4f7f120fd5d715f9896ebe95f9eb 657 PRINTS PR00364 Disease resistance protein signature 215 229 4.6E-11 T 28-03-2018 CU254_RS29850 b9cf4f7f120fd5d715f9896ebe95f9eb 657 PRINTS PR00364 Disease resistance protein signature 52 67 4.6E-11 T 28-03-2018 CU254_RS29850 b9cf4f7f120fd5d715f9896ebe95f9eb 657 PRINTS PR00364 Disease resistance protein signature 130 144 4.6E-11 T 28-03-2018 CU254_RS29850 b9cf4f7f120fd5d715f9896ebe95f9eb 657 SUPERFAMILY SSF48452 512 654 4.74E-17 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS29850 b9cf4f7f120fd5d715f9896ebe95f9eb 657 SUPERFAMILY SSF52540 20 275 5.71E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS29850 b9cf4f7f120fd5d715f9896ebe95f9eb 657 Gene3D G3DSA:3.40.50.300 17 175 3.2E-13 T 28-03-2018 CU254_RS29850 b9cf4f7f120fd5d715f9896ebe95f9eb 657 Gene3D G3DSA:1.25.40.10 456 509 3.2E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS29850 b9cf4f7f120fd5d715f9896ebe95f9eb 657 Gene3D G3DSA:1.25.40.10 510 548 2.0E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS05615 a0d12ead1ded3edb0cc4f8998b953c7d 189 Gene3D G3DSA:1.10.357.10 6 189 2.5E-29 T 28-03-2018 CU254_RS05615 a0d12ead1ded3edb0cc4f8998b953c7d 189 SUPERFAMILY SSF46689 3 67 5.13E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS05615 a0d12ead1ded3edb0cc4f8998b953c7d 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 56 5.2E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS32830 11365f6d481a3a008271ab1feb97cee1 561 Pfam PF12849 PBP superfamily domain 275 530 6.1E-20 T 28-03-2018 IPR024370 PBP domain CU254_RS32830 11365f6d481a3a008271ab1feb97cee1 561 Gene3D G3DSA:3.40.190.10 280 412 4.1E-16 T 28-03-2018 CU254_RS32830 11365f6d481a3a008271ab1feb97cee1 561 SUPERFAMILY SSF53850 282 545 7.1E-41 T 28-03-2018 CU254_RS32830 11365f6d481a3a008271ab1feb97cee1 561 Gene3D G3DSA:3.40.190.10 434 549 6.5E-9 T 28-03-2018 CU254_RS22120 d50a0c3da6fa2b5eb5cce5df1563c7c5 424 Pfam PF04434 SWIM zinc finger 57 75 3.7E-5 T 28-03-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 CU254_RS01665 e53717ad6569828131195a9fbda0a4af 282 Pfam PF04672 S-adenosyl methyltransferase 11 282 2.8E-79 T 28-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CU254_RS01665 e53717ad6569828131195a9fbda0a4af 282 SUPERFAMILY SSF53335 4 263 3.01E-44 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS01665 e53717ad6569828131195a9fbda0a4af 282 Gene3D G3DSA:3.40.50.150 2 282 1.6E-46 T 28-03-2018 CU254_RS01665 e53717ad6569828131195a9fbda0a4af 282 PIRSF PIRSF017393 2 282 2.5E-81 T 28-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CU254_RS42305 93ec7113227afd5bf68194662df8f9ef 529 Pfam PF13360 PQQ-like domain 183 314 6.2E-8 T 28-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat CU254_RS42305 93ec7113227afd5bf68194662df8f9ef 529 SUPERFAMILY SSF50998 182 305 9.42E-9 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CU254_RS42305 93ec7113227afd5bf68194662df8f9ef 529 SUPERFAMILY SSF50998 378 452 9.42E-9 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CU254_RS42305 93ec7113227afd5bf68194662df8f9ef 529 Gene3D G3DSA:2.130.10.10 178 516 2.1E-8 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CU254_RS32315 2c13c0d2fc8dbf120479f54eb6256ad7 525 SUPERFAMILY SSF53474 78 143 1.79E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS32315 2c13c0d2fc8dbf120479f54eb6256ad7 525 SUPERFAMILY SSF53474 187 297 1.79E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS32315 2c13c0d2fc8dbf120479f54eb6256ad7 525 SUPERFAMILY SSF53474 393 492 1.79E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS32315 2c13c0d2fc8dbf120479f54eb6256ad7 525 Gene3D G3DSA:3.40.50.1820 24 505 1.5E-33 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS32315 2c13c0d2fc8dbf120479f54eb6256ad7 525 Pfam PF08386 TAP-like protein 422 516 3.6E-23 T 28-03-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal CU254_RS32315 2c13c0d2fc8dbf120479f54eb6256ad7 525 Pfam PF00561 alpha/beta hydrolase fold 98 271 3.2E-16 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS40850 6b2d34cfdfc646c4f6586e98913bfe07 161 SUPERFAMILY SSF46785 11 121 1.49E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS40850 6b2d34cfdfc646c4f6586e98913bfe07 161 Gene3D G3DSA:1.10.10.10 5 158 5.1E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS40850 6b2d34cfdfc646c4f6586e98913bfe07 161 Pfam PF12802 MarR family 28 87 2.7E-9 T 28-03-2018 CU254_RS16395 fd37e20eb1ede0f82eebb738d99ce4f3 218 Gene3D G3DSA:1.10.10.10 4 73 2.3E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS16395 fd37e20eb1ede0f82eebb738d99ce4f3 218 SUPERFAMILY SSF46785 9 74 6.31E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS16395 fd37e20eb1ede0f82eebb738d99ce4f3 218 Gene3D G3DSA:1.20.120.530 74 217 8.8E-26 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS16395 fd37e20eb1ede0f82eebb738d99ce4f3 218 SUPERFAMILY SSF48008 76 200 1.02E-21 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS16395 fd37e20eb1ede0f82eebb738d99ce4f3 218 Pfam PF07729 FCD domain 80 199 6.7E-19 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS16395 fd37e20eb1ede0f82eebb738d99ce4f3 218 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 30 44 2.5E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS16395 fd37e20eb1ede0f82eebb738d99ce4f3 218 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 44 60 2.5E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS16395 fd37e20eb1ede0f82eebb738d99ce4f3 218 Pfam PF00392 Bacterial regulatory proteins, gntR family 9 66 9.6E-18 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS16395 fd37e20eb1ede0f82eebb738d99ce4f3 218 SMART SM00895 80 200 3.2E-14 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS16395 fd37e20eb1ede0f82eebb738d99ce4f3 218 SMART SM00345 12 70 5.6E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS18295 71c1c86ff774040606519918f4a87ffb 325 ProSitePatterns PS01218 TatC family signature. 189 208 - T 28-03-2018 IPR019820 Sec-independent periplasmic protein translocase, conserved site CU254_RS18295 71c1c86ff774040606519918f4a87ffb 325 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 121 139 2.1E-36 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CU254_RS18295 71c1c86ff774040606519918f4a87ffb 325 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 139 165 2.1E-36 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CU254_RS18295 71c1c86ff774040606519918f4a87ffb 325 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 29 56 2.1E-36 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CU254_RS18295 71c1c86ff774040606519918f4a87ffb 325 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 189 217 2.1E-36 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CU254_RS18295 71c1c86ff774040606519918f4a87ffb 325 Pfam PF00902 Sec-independent protein translocase protein (TatC) 32 255 1.5E-58 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CU254_RS18295 71c1c86ff774040606519918f4a87ffb 325 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 24 275 17.226 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CU254_RS18295 71c1c86ff774040606519918f4a87ffb 325 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 30 262 1.0E-63 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CU254_RS34010 5468dc6be7ca1f846a2feb611e89ab08 215 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 194 7.5E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS34010 5468dc6be7ca1f846a2feb611e89ab08 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 1.6E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS34010 5468dc6be7ca1f846a2feb611e89ab08 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 1.6E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS34010 5468dc6be7ca1f846a2feb611e89ab08 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 1.6E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS34010 5468dc6be7ca1f846a2feb611e89ab08 215 SMART SM00448 1 121 2.5E-11 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS34010 5468dc6be7ca1f846a2feb611e89ab08 215 Gene3D G3DSA:3.40.50.2300 1 132 1.7E-27 T 28-03-2018 CU254_RS34010 5468dc6be7ca1f846a2feb611e89ab08 215 Pfam PF00072 Response regulator receiver domain 3 97 4.9E-15 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS34010 5468dc6be7ca1f846a2feb611e89ab08 215 SMART SM00421 147 209 3.5E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS34010 5468dc6be7ca1f846a2feb611e89ab08 215 SUPERFAMILY SSF52172 1 179 2.72E-22 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS34010 5468dc6be7ca1f846a2feb611e89ab08 215 Gene3D G3DSA:1.10.10.10 133 214 7.0E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS06545 d1c9369f76e9b395ad8bf2f0cbafc489 531 Pfam PF13649 Methyltransferase domain 373 465 1.1E-16 T 28-03-2018 CU254_RS06545 d1c9369f76e9b395ad8bf2f0cbafc489 531 SUPERFAMILY SSF53335 335 508 1.41E-39 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS06545 d1c9369f76e9b395ad8bf2f0cbafc489 531 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 2.5E-11 T 28-03-2018 CU254_RS06545 d1c9369f76e9b395ad8bf2f0cbafc489 531 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 2.5E-11 T 28-03-2018 CU254_RS06545 d1c9369f76e9b395ad8bf2f0cbafc489 531 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 275 2.5E-11 T 28-03-2018 CU254_RS06545 d1c9369f76e9b395ad8bf2f0cbafc489 531 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 285 1.5E-13 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS06545 d1c9369f76e9b395ad8bf2f0cbafc489 531 Gene3D G3DSA:3.50.50.60 2 169 2.5E-23 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS06545 d1c9369f76e9b395ad8bf2f0cbafc489 531 Gene3D G3DSA:3.40.50.150 302 530 8.7E-34 T 28-03-2018 CU254_RS06545 d1c9369f76e9b395ad8bf2f0cbafc489 531 SUPERFAMILY SSF51905 2 298 5.76E-32 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS06545 d1c9369f76e9b395ad8bf2f0cbafc489 531 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 103 111 1.1E-15 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CU254_RS06545 d1c9369f76e9b395ad8bf2f0cbafc489 531 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 125 137 1.1E-15 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CU254_RS06545 d1c9369f76e9b395ad8bf2f0cbafc489 531 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 140 164 1.1E-15 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CU254_RS06545 d1c9369f76e9b395ad8bf2f0cbafc489 531 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 6 28 1.1E-15 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CU254_RS06545 d1c9369f76e9b395ad8bf2f0cbafc489 531 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 263 281 1.1E-15 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CU254_RS06545 d1c9369f76e9b395ad8bf2f0cbafc489 531 Gene3D G3DSA:3.50.50.60 170 301 3.2E-10 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS26775 578428a241cb534affc41d443429638b 429 ProSitePatterns PS00216 Sugar transport proteins signature 1. 298 315 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CU254_RS26775 578428a241cb534affc41d443429638b 429 Gene3D G3DSA:1.20.1250.20 11 225 6.8E-25 T 28-03-2018 CU254_RS26775 578428a241cb534affc41d443429638b 429 Gene3D G3DSA:1.20.1250.20 226 429 2.6E-24 T 28-03-2018 CU254_RS26775 578428a241cb534affc41d443429638b 429 Pfam PF00083 Sugar (and other) transporter 21 428 5.8E-23 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CU254_RS26775 578428a241cb534affc41d443429638b 429 SUPERFAMILY SSF103473 17 422 4.32E-64 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS03090 006dfe470d72e3e58bf004a034355056 542 SUPERFAMILY SSF53738 211 308 1.14E-18 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CU254_RS03090 006dfe470d72e3e58bf004a034355056 542 Gene3D G3DSA:3.40.120.10 213 331 5.5E-26 T 28-03-2018 CU254_RS03090 006dfe470d72e3e58bf004a034355056 542 SUPERFAMILY SSF53738 45 214 5.1E-42 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CU254_RS03090 006dfe470d72e3e58bf004a034355056 542 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 151 160 - T 28-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CU254_RS03090 006dfe470d72e3e58bf004a034355056 542 SUPERFAMILY SSF53738 301 437 5.49E-26 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CU254_RS03090 006dfe470d72e3e58bf004a034355056 542 Gene3D G3DSA:3.40.120.10 22 212 1.7E-54 T 28-03-2018 CU254_RS03090 006dfe470d72e3e58bf004a034355056 542 Gene3D G3DSA:3.40.120.10 332 433 3.8E-32 T 28-03-2018 CU254_RS03090 006dfe470d72e3e58bf004a034355056 542 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 56 191 6.3E-39 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CU254_RS03090 006dfe470d72e3e58bf004a034355056 542 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 293 308 2.6E-8 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CU254_RS03090 006dfe470d72e3e58bf004a034355056 542 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 226 245 2.6E-8 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CU254_RS03090 006dfe470d72e3e58bf004a034355056 542 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 150 164 2.6E-8 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CU254_RS03090 006dfe470d72e3e58bf004a034355056 542 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 223 308 6.9E-22 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CU254_RS03090 006dfe470d72e3e58bf004a034355056 542 Gene3D G3DSA:3.30.310.50 434 540 3.3E-15 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CU254_RS03090 006dfe470d72e3e58bf004a034355056 542 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 487 510 1.5E-6 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CU254_RS03090 006dfe470d72e3e58bf004a034355056 542 SUPERFAMILY SSF55957 438 533 1.7E-11 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CU254_RS03090 006dfe470d72e3e58bf004a034355056 542 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 321 432 7.2E-16 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CU254_RS34475 92c9e053e0acbf9311038bdd5fd3549a 413 Pfam PF09661 Protein of unknown function (DUF2398) 20 400 1.7E-110 T 28-03-2018 IPR013494 Conserved hypothetical protein CHP02678 CU254_RS34475 92c9e053e0acbf9311038bdd5fd3549a 413 TIGRFAM TIGR02678 TIGR02678: TIGR02678 family protein 20 402 3.1E-99 T 28-03-2018 IPR013494 Conserved hypothetical protein CHP02678 CU254_RS34025 be8a8f82247cfad165215055d379b71d 263 Pfam PF00440 Bacterial regulatory proteins, tetR family 82 126 1.0E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS34025 be8a8f82247cfad165215055d379b71d 263 Gene3D G3DSA:1.10.357.10 134 262 1.2E-9 T 28-03-2018 CU254_RS34025 be8a8f82247cfad165215055d379b71d 263 Gene3D G3DSA:1.10.10.60 113 133 2.6E-9 T 28-03-2018 CU254_RS34025 be8a8f82247cfad165215055d379b71d 263 Gene3D G3DSA:1.10.10.60 56 112 2.8E-14 T 28-03-2018 CU254_RS34025 be8a8f82247cfad165215055d379b71d 263 SUPERFAMILY SSF46689 77 142 1.03E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS34025 be8a8f82247cfad165215055d379b71d 263 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 82 95 1.4E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS34025 be8a8f82247cfad165215055d379b71d 263 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 102 125 1.4E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS09525 cfb28d4be92ce23b09c7535c3023e26c 166 PRINTS PR01576 Peptide deformylase signature 118 147 2.6E-24 T 28-03-2018 IPR023635 Peptide deformylase CU254_RS09525 cfb28d4be92ce23b09c7535c3023e26c 166 PRINTS PR01576 Peptide deformylase signature 33 62 2.6E-24 T 28-03-2018 IPR023635 Peptide deformylase CU254_RS09525 cfb28d4be92ce23b09c7535c3023e26c 166 PRINTS PR01576 Peptide deformylase signature 99 117 2.6E-24 T 28-03-2018 IPR023635 Peptide deformylase CU254_RS09525 cfb28d4be92ce23b09c7535c3023e26c 166 PRINTS PR01576 Peptide deformylase signature 87 98 2.6E-24 T 28-03-2018 IPR023635 Peptide deformylase CU254_RS09525 cfb28d4be92ce23b09c7535c3023e26c 166 SUPERFAMILY SSF56420 1 155 6.28E-49 T 28-03-2018 IPR023635 Peptide deformylase CU254_RS09525 cfb28d4be92ce23b09c7535c3023e26c 166 PIRSF PIRSF004749 1 162 1.0E-39 T 28-03-2018 IPR023635 Peptide deformylase CU254_RS09525 cfb28d4be92ce23b09c7535c3023e26c 166 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 6 156 2.9E-35 T 28-03-2018 IPR023635 Peptide deformylase CU254_RS09525 cfb28d4be92ce23b09c7535c3023e26c 166 Pfam PF01327 Polypeptide deformylase 3 150 5.8E-39 T 28-03-2018 IPR023635 Peptide deformylase CU254_RS09525 cfb28d4be92ce23b09c7535c3023e26c 166 Hamap MF_00163 Peptide deformylase [def]. 2 160 25.564 T 28-03-2018 IPR023635 Peptide deformylase CU254_RS09525 cfb28d4be92ce23b09c7535c3023e26c 166 Gene3D G3DSA:3.90.45.10 1 161 2.0E-49 T 28-03-2018 IPR023635 Peptide deformylase CU254_RS03315 b7d500759f97c853492a600a8ad11a2a 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 50 65 2.8E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS03315 b7d500759f97c853492a600a8ad11a2a 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 97 110 2.8E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS03315 b7d500759f97c853492a600a8ad11a2a 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 111 124 2.8E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS03315 b7d500759f97c853492a600a8ad11a2a 286 PRINTS PR00412 Epoxide hydrolase signature 111 124 4.0E-7 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS03315 b7d500759f97c853492a600a8ad11a2a 286 PRINTS PR00412 Epoxide hydrolase signature 97 110 4.0E-7 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS03315 b7d500759f97c853492a600a8ad11a2a 286 PRINTS PR00412 Epoxide hydrolase signature 261 283 4.0E-7 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS03315 b7d500759f97c853492a600a8ad11a2a 286 PRINTS PR00412 Epoxide hydrolase signature 31 49 4.0E-7 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS03315 b7d500759f97c853492a600a8ad11a2a 286 SUPERFAMILY SSF53474 3 286 1.31E-61 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS03315 b7d500759f97c853492a600a8ad11a2a 286 Gene3D G3DSA:3.40.50.1820 2 286 3.4E-48 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS03315 b7d500759f97c853492a600a8ad11a2a 286 Pfam PF00561 alpha/beta hydrolase fold 26 132 4.0E-20 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS39630 97a457376ef1d8db4c5ddf2b8cd29fc0 474 SUPERFAMILY SSF53720 7 472 1.1E-129 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CU254_RS39630 97a457376ef1d8db4c5ddf2b8cd29fc0 474 Gene3D G3DSA:3.40.605.10 4 263 2.0E-69 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CU254_RS39630 97a457376ef1d8db4c5ddf2b8cd29fc0 474 Gene3D G3DSA:3.40.309.10 264 456 7.4E-61 T 28-03-2018 CU254_RS39630 97a457376ef1d8db4c5ddf2b8cd29fc0 474 Pfam PF00171 Aldehyde dehydrogenase family 14 468 2.8E-133 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CU254_RS03965 f4bdb062215d2262700795a3e54519c8 302 Pfam PF11583 P-aminobenzoate N-oxygenase AurF 8 282 5.8E-106 T 28-03-2018 IPR025859 P-aminobenzoate N-oxygenase AurF CU254_RS03965 f4bdb062215d2262700795a3e54519c8 302 SUPERFAMILY SSF47240 16 220 8.11E-7 T 28-03-2018 IPR009078 Ferritin-like superfamily CU254_RS03965 f4bdb062215d2262700795a3e54519c8 302 Gene3D G3DSA:1.10.620.20 6 257 1.3E-37 T 28-03-2018 CU254_RS32115 fc1348523298ca0f069063548a99b61c 315 Pfam PF13602 Zinc-binding dehydrogenase 185 313 4.1E-16 T 28-03-2018 CU254_RS32115 fc1348523298ca0f069063548a99b61c 315 Gene3D G3DSA:3.90.180.10 243 315 9.7E-5 T 28-03-2018 CU254_RS32115 fc1348523298ca0f069063548a99b61c 315 SMART SM00829 10 313 4.2E-12 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CU254_RS32115 fc1348523298ca0f069063548a99b61c 315 Gene3D G3DSA:3.90.180.10 1 144 2.7E-45 T 28-03-2018 CU254_RS32115 fc1348523298ca0f069063548a99b61c 315 SUPERFAMILY SSF50129 8 147 6.24E-36 T 28-03-2018 IPR011032 GroES-like CU254_RS32115 fc1348523298ca0f069063548a99b61c 315 Gene3D G3DSA:3.40.50.720 145 242 2.3E-25 T 28-03-2018 CU254_RS32115 fc1348523298ca0f069063548a99b61c 315 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 91 5.3E-8 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CU254_RS32115 fc1348523298ca0f069063548a99b61c 315 SUPERFAMILY SSF51735 118 273 9.61E-31 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS39055 d46dfa5b20927c8a2b3c52b74b986fe1 245 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 185 3.1E-4 T 28-03-2018 CU254_RS39055 d46dfa5b20927c8a2b3c52b74b986fe1 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 4.8E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS39055 d46dfa5b20927c8a2b3c52b74b986fe1 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 4.8E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS39055 d46dfa5b20927c8a2b3c52b74b986fe1 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 4.8E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS39055 d46dfa5b20927c8a2b3c52b74b986fe1 245 Gene3D G3DSA:3.40.50.10090 1 45 3.5E-11 T 28-03-2018 CU254_RS39055 d46dfa5b20927c8a2b3c52b74b986fe1 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 242 4.7E-60 T 28-03-2018 CU254_RS39055 d46dfa5b20927c8a2b3c52b74b986fe1 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 4.3E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS39055 d46dfa5b20927c8a2b3c52b74b986fe1 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 4.3E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS39055 d46dfa5b20927c8a2b3c52b74b986fe1 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 4.3E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS39055 d46dfa5b20927c8a2b3c52b74b986fe1 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 4.3E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS39055 d46dfa5b20927c8a2b3c52b74b986fe1 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 4.3E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS39055 d46dfa5b20927c8a2b3c52b74b986fe1 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 4.3E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS39055 d46dfa5b20927c8a2b3c52b74b986fe1 245 Gene3D G3DSA:3.40.50.720 46 245 1.9E-63 T 28-03-2018 CU254_RS39055 d46dfa5b20927c8a2b3c52b74b986fe1 245 SUPERFAMILY SSF51735 4 243 6.43E-80 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS42110 b1e28f37689bdc1902f670666992c62a 367 Gene3D G3DSA:1.10.10.60 318 367 2.9E-5 T 28-03-2018 CU254_RS42110 b1e28f37689bdc1902f670666992c62a 367 Pfam PF12833 Helix-turn-helix domain 286 366 7.3E-14 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS42110 b1e28f37689bdc1902f670666992c62a 367 Pfam PF14525 AraC-binding-like domain 64 239 9.1E-43 T 28-03-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like CU254_RS42110 b1e28f37689bdc1902f670666992c62a 367 SMART SM00342 280 365 3.4E-10 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS42110 b1e28f37689bdc1902f670666992c62a 367 Gene3D G3DSA:1.10.10.60 261 317 9.3E-6 T 28-03-2018 CU254_RS11000 4ff71474d15ae29fbce030e51f4db3f1 220 SUPERFAMILY SSF52172 1 168 1.13E-32 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS11000 4ff71474d15ae29fbce030e51f4db3f1 220 Gene3D G3DSA:1.10.10.10 115 220 1.4E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS11000 4ff71474d15ae29fbce030e51f4db3f1 220 SMART SM00448 1 109 4.2E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS11000 4ff71474d15ae29fbce030e51f4db3f1 220 Pfam PF00486 Transcriptional regulatory protein, C terminal 144 213 6.2E-21 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS11000 4ff71474d15ae29fbce030e51f4db3f1 220 Pfam PF00072 Response regulator receiver domain 1 110 8.0E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS11000 4ff71474d15ae29fbce030e51f4db3f1 220 Gene3D G3DSA:3.40.50.2300 1 114 4.6E-30 T 28-03-2018 CU254_RS11000 4ff71474d15ae29fbce030e51f4db3f1 220 SMART SM00862 142 214 1.3E-19 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS24000 972c617dba36cf8c42c853521cda6870 214 Gene3D G3DSA:1.20.58.350 15 61 1.2E-22 T 28-03-2018 CU254_RS24000 972c617dba36cf8c42c853521cda6870 214 SUPERFAMILY SSF54637 5 199 5.1E-39 T 28-03-2018 IPR029069 HotDog domain CU254_RS24000 972c617dba36cf8c42c853521cda6870 214 Gene3D G3DSA:3.10.129.10 62 206 1.5E-25 T 28-03-2018 CU254_RS24000 972c617dba36cf8c42c853521cda6870 214 Pfam PF03061 Thioesterase superfamily 118 189 1.3E-5 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CU254_RS04790 f0e2cd39784b442b7ee69d1366894683 447 SUPERFAMILY SSF56112 106 169 1.34E-27 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS04790 f0e2cd39784b442b7ee69d1366894683 447 SUPERFAMILY SSF56112 205 319 1.34E-27 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS04790 f0e2cd39784b442b7ee69d1366894683 447 Gene3D G3DSA:3.30.200.20 113 250 7.4E-25 T 28-03-2018 CU254_RS04790 f0e2cd39784b442b7ee69d1366894683 447 Pfam PF03109 ABC1 family 123 238 4.3E-32 T 28-03-2018 IPR004147 UbiB domain CU254_RS04790 f0e2cd39784b442b7ee69d1366894683 447 Gene3D G3DSA:1.10.510.10 257 354 2.3E-5 T 28-03-2018 CU254_RS37130 428a414572aba57a4be83ca23d9e70cc 775 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 491 594 9.8E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS37130 428a414572aba57a4be83ca23d9e70cc 775 SUPERFAMILY SSF55874 480 595 3.54E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS37130 428a414572aba57a4be83ca23d9e70cc 775 Gene3D G3DSA:3.30.565.10 409 595 4.4E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS37130 428a414572aba57a4be83ca23d9e70cc 775 SMART SM00387 487 596 1.2E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS37130 428a414572aba57a4be83ca23d9e70cc 775 SMART SM00304 306 375 2.4E-4 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS21770 511f0a3f72c85aac2721da171ceeeae7 293 SUPERFAMILY SSF51197 8 289 1.14E-53 T 28-03-2018 CU254_RS21770 511f0a3f72c85aac2721da171ceeeae7 293 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 11 269 6.5E-35 T 28-03-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 CU254_RS21770 511f0a3f72c85aac2721da171ceeeae7 293 Gene3D G3DSA:3.60.130.10 2 292 5.2E-44 T 28-03-2018 CU254_RS30295 478b8910f617119beb364054ed97c324 511 Pfam PF01494 FAD binding domain 3 357 5.0E-67 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CU254_RS30295 478b8910f617119beb364054ed97c324 511 Gene3D G3DSA:3.50.50.60 2 402 1.7E-64 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS30295 478b8910f617119beb364054ed97c324 511 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 146 161 6.1E-41 T 28-03-2018 CU254_RS30295 478b8910f617119beb364054ed97c324 511 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 343 359 6.1E-41 T 28-03-2018 CU254_RS30295 478b8910f617119beb364054ed97c324 511 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 6.1E-41 T 28-03-2018 CU254_RS30295 478b8910f617119beb364054ed97c324 511 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 307 323 6.1E-41 T 28-03-2018 CU254_RS30295 478b8910f617119beb364054ed97c324 511 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 292 307 6.1E-41 T 28-03-2018 CU254_RS30295 478b8910f617119beb364054ed97c324 511 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 325 343 6.1E-41 T 28-03-2018 CU254_RS30295 478b8910f617119beb364054ed97c324 511 SUPERFAMILY SSF51905 3 167 4.87E-57 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS30295 478b8910f617119beb364054ed97c324 511 SUPERFAMILY SSF51905 279 369 4.87E-57 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS02690 2843da9c08093fc6854ff0032a9b1226 213 SUPERFAMILY SSF53335 26 204 3.05E-31 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS02690 2843da9c08093fc6854ff0032a9b1226 213 Pfam PF01564 Spermine/spermidine synthase domain 58 173 4.9E-7 T 28-03-2018 CU254_RS02690 2843da9c08093fc6854ff0032a9b1226 213 Gene3D G3DSA:3.40.50.150 41 213 3.1E-20 T 28-03-2018 CU254_RS11580 8f556e86e9f0d77a68f8cf31f9fcb7fc 168 SUPERFAMILY SSF52507 10 148 1.83E-14 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CU254_RS11580 8f556e86e9f0d77a68f8cf31f9fcb7fc 168 Pfam PF02441 Flavoprotein 12 148 2.4E-9 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CU254_RS11580 8f556e86e9f0d77a68f8cf31f9fcb7fc 168 Gene3D G3DSA:3.40.50.1950 2 162 1.1E-17 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CU254_RS17300 3eea8577b316e775b9ccc156195585db 831 Gene3D G3DSA:3.40.50.300 200 348 1.6E-17 T 28-03-2018 CU254_RS17300 3eea8577b316e775b9ccc156195585db 831 Pfam PF02151 UvrB/uvrC motif 423 455 5.5E-8 T 28-03-2018 IPR001943 UVR domain GO:0005515 CU254_RS17300 3eea8577b316e775b9ccc156195585db 831 Gene3D G3DSA:3.40.50.300 498 720 1.8E-53 T 28-03-2018 CU254_RS17300 3eea8577b316e775b9ccc156195585db 831 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 93 142 3.8E-17 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CU254_RS17300 3eea8577b316e775b9ccc156195585db 831 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 16 68 6.3E-18 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CU254_RS17300 3eea8577b316e775b9ccc156195585db 831 SUPERFAMILY SSF52540 492 806 1.12E-76 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS17300 3eea8577b316e775b9ccc156195585db 831 Gene3D G3DSA:1.10.8.60 350 493 7.9E-43 T 28-03-2018 CU254_RS17300 3eea8577b316e775b9ccc156195585db 831 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 721 801 6.7E-26 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CU254_RS17300 3eea8577b316e775b9ccc156195585db 831 Gene3D G3DSA:1.10.1780.10 79 199 2.9E-28 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CU254_RS17300 3eea8577b316e775b9ccc156195585db 831 Gene3D G3DSA:1.10.1780.10 1 78 2.9E-28 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CU254_RS17300 3eea8577b316e775b9ccc156195585db 831 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 621 639 1.2E-38 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CU254_RS17300 3eea8577b316e775b9ccc156195585db 831 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 592 610 1.2E-38 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CU254_RS17300 3eea8577b316e775b9ccc156195585db 831 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 654 668 1.2E-38 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CU254_RS17300 3eea8577b316e775b9ccc156195585db 831 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 547 565 1.2E-38 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CU254_RS17300 3eea8577b316e775b9ccc156195585db 831 SUPERFAMILY SSF81923 3 153 5.49E-33 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CU254_RS17300 3eea8577b316e775b9ccc156195585db 831 Gene3D G3DSA:1.10.8.60 721 818 1.3E-23 T 28-03-2018 CU254_RS17300 3eea8577b316e775b9ccc156195585db 831 SMART SM01086 721 810 8.0E-35 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CU254_RS17300 3eea8577b316e775b9ccc156195585db 831 SMART SM00382 543 722 1.8E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS17300 3eea8577b316e775b9ccc156195585db 831 SMART SM00382 206 350 5.7E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS17300 3eea8577b316e775b9ccc156195585db 831 Pfam PF07724 AAA domain (Cdc48 subfamily) 542 715 4.5E-50 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CU254_RS17300 3eea8577b316e775b9ccc156195585db 831 SUPERFAMILY SSF52540 169 468 4.28E-74 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS17300 3eea8577b316e775b9ccc156195585db 831 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 211 323 7.5E-13 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CU254_RS17300 3eea8577b316e775b9ccc156195585db 831 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 301 313 - T 28-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 CU254_RS39190 95e4b6f64c070234c4409f92d2ea825c 316 Gene3D G3DSA:3.40.50.20 2 78 5.6E-21 T 28-03-2018 CU254_RS39190 95e4b6f64c070234c4409f92d2ea825c 316 Gene3D G3DSA:3.30.1490.20 79 173 9.8E-19 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CU254_RS39190 95e4b6f64c070234c4409f92d2ea825c 316 Gene3D G3DSA:3.30.470.20 174 313 7.5E-34 T 28-03-2018 CU254_RS39190 95e4b6f64c070234c4409f92d2ea825c 316 SUPERFAMILY SSF56059 97 308 2.83E-44 T 28-03-2018 CU254_RS39190 95e4b6f64c070234c4409f92d2ea825c 316 SUPERFAMILY SSF52440 5 97 1.06E-21 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CU254_RS39190 95e4b6f64c070234c4409f92d2ea825c 316 Pfam PF07478 D-ala D-ala ligase C-terminus 105 308 3.5E-42 T 28-03-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CU254_RS39190 95e4b6f64c070234c4409f92d2ea825c 316 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 4 312 27.965 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CU254_RS39190 95e4b6f64c070234c4409f92d2ea825c 316 PIRSF PIRSF039102 2 45 7.3E-7 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CU254_RS39190 95e4b6f64c070234c4409f92d2ea825c 316 PIRSF PIRSF039102 39 316 2.7E-65 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CU254_RS39190 95e4b6f64c070234c4409f92d2ea825c 316 Pfam PF01820 D-ala D-ala ligase N-terminus 6 86 8.4E-14 T 28-03-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CU254_RS26460 634d455ecf9bc2dd95b3234fbd5e0b1c 250 SUPERFAMILY SSF75217 79 249 4.71E-43 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CU254_RS26460 634d455ecf9bc2dd95b3234fbd5e0b1c 250 PIRSF PIRSF015601 7 249 2.7E-48 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CU254_RS26460 634d455ecf9bc2dd95b3234fbd5e0b1c 250 Gene3D G3DSA:2.40.240.20 4 76 1.1E-18 T 28-03-2018 CU254_RS26460 634d455ecf9bc2dd95b3234fbd5e0b1c 250 Gene3D G3DSA:3.40.1280.10 78 250 2.6E-51 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CU254_RS26460 634d455ecf9bc2dd95b3234fbd5e0b1c 250 Pfam PF04452 RNA methyltransferase 22 242 1.4E-57 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CU254_RS26460 634d455ecf9bc2dd95b3234fbd5e0b1c 250 SUPERFAMILY SSF88697 8 66 1.74E-9 T 28-03-2018 IPR015947 PUA-like domain CU254_RS26460 634d455ecf9bc2dd95b3234fbd5e0b1c 250 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 17 246 4.5E-39 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CU254_RS22035 298b5ac8f1939834df6e436de8ec8504 360 SUPERFAMILY SSF51735 150 322 1.75E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS22035 298b5ac8f1939834df6e436de8ec8504 360 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 146 1.7E-28 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CU254_RS22035 298b5ac8f1939834df6e436de8ec8504 360 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CU254_RS22035 298b5ac8f1939834df6e436de8ec8504 360 Gene3D G3DSA:3.40.50.10730 171 352 8.1E-32 T 28-03-2018 CU254_RS22035 298b5ac8f1939834df6e436de8ec8504 360 Pfam PF00107 Zinc-binding dehydrogenase 188 306 1.2E-23 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CU254_RS22035 298b5ac8f1939834df6e436de8ec8504 360 SMART SM00829 11 356 2.8E-8 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CU254_RS22035 298b5ac8f1939834df6e436de8ec8504 360 SUPERFAMILY SSF50129 310 356 1.51E-7 T 28-03-2018 IPR011032 GroES-like CU254_RS22035 298b5ac8f1939834df6e436de8ec8504 360 SUPERFAMILY SSF50129 3 179 2.43E-50 T 28-03-2018 IPR011032 GroES-like CU254_RS22035 298b5ac8f1939834df6e436de8ec8504 360 Gene3D G3DSA:3.90.180.10 2 170 6.7E-51 T 28-03-2018 CU254_RS31290 7bc8d14cb0f45d0322ab4728e0c762f8 261 PRINTS PR00123 ATP synthase A subunit signature 240 255 1.1E-16 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CU254_RS31290 7bc8d14cb0f45d0322ab4728e0c762f8 261 PRINTS PR00123 ATP synthase A subunit signature 92 108 1.1E-16 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CU254_RS31290 7bc8d14cb0f45d0322ab4728e0c762f8 261 PRINTS PR00123 ATP synthase A subunit signature 178 200 1.1E-16 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CU254_RS31290 7bc8d14cb0f45d0322ab4728e0c762f8 261 SUPERFAMILY SSF81336 84 254 4.84E-31 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CU254_RS31290 7bc8d14cb0f45d0322ab4728e0c762f8 261 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 18 255 3.8E-38 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CU254_RS31290 7bc8d14cb0f45d0322ab4728e0c762f8 261 Gene3D G3DSA:1.20.120.220 80 261 3.8E-32 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CU254_RS31290 7bc8d14cb0f45d0322ab4728e0c762f8 261 Hamap MF_01393 ATP synthase subunit a [atpB]. 17 260 12.465 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CU254_RS31290 7bc8d14cb0f45d0322ab4728e0c762f8 261 Pfam PF00119 ATP synthase A chain 34 253 2.5E-46 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CU254_RS16735 75a65d05a453c03748dde2ae859c66cf 340 SUPERFAMILY SSF51679 7 333 3.4E-57 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS16735 75a65d05a453c03748dde2ae859c66cf 340 Pfam PF00296 Luciferase-like monooxygenase 8 250 1.3E-26 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS16735 75a65d05a453c03748dde2ae859c66cf 340 Gene3D G3DSA:3.20.20.30 2 338 6.2E-59 T 28-03-2018 CU254_RS37900 515f05285012e85832efbd13adf174da 419 SUPERFAMILY SSF52440 2 101 1.73E-29 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CU254_RS37900 515f05285012e85832efbd13adf174da 419 SUPERFAMILY SSF51246 320 410 1.41E-24 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CU254_RS37900 515f05285012e85832efbd13adf174da 419 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 287 9.3E-68 T 28-03-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CU254_RS37900 515f05285012e85832efbd13adf174da 419 SMART SM01209 101 287 5.4E-111 T 28-03-2018 CU254_RS37900 515f05285012e85832efbd13adf174da 419 Gene3D G3DSA:3.90.600.10 322 412 2.5E-28 T 28-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CU254_RS37900 515f05285012e85832efbd13adf174da 419 Gene3D G3DSA:3.30.1490.20 85 181 3.9E-19 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CU254_RS37900 515f05285012e85832efbd13adf174da 419 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 2 100 1.4E-29 T 28-03-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CU254_RS37900 515f05285012e85832efbd13adf174da 419 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 323 409 2.3E-27 T 28-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CU254_RS37900 515f05285012e85832efbd13adf174da 419 Gene3D G3DSA:3.30.470.20 183 320 2.6E-57 T 28-03-2018 CU254_RS37900 515f05285012e85832efbd13adf174da 419 Gene3D G3DSA:3.40.50.20 2 84 5.8E-32 T 28-03-2018 CU254_RS37900 515f05285012e85832efbd13adf174da 419 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 281 288 - T 28-03-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CU254_RS37900 515f05285012e85832efbd13adf174da 419 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 2 411 5.0E-150 T 28-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CU254_RS37900 515f05285012e85832efbd13adf174da 419 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 411 39.996 T 28-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CU254_RS37900 515f05285012e85832efbd13adf174da 419 SMART SM01210 322 411 7.4E-40 T 28-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CU254_RS37900 515f05285012e85832efbd13adf174da 419 SUPERFAMILY SSF56059 102 312 4.28E-50 T 28-03-2018 CU254_RS19510 e9f1eb0376132d80abad28a36fb11bf6 275 SUPERFAMILY SSF63992 1 267 3.01E-87 T 28-03-2018 IPR007035 Peptidase M55, D-aminopeptidase CU254_RS19510 e9f1eb0376132d80abad28a36fb11bf6 275 Gene3D G3DSA:3.30.1360.130 211 267 1.1E-16 T 28-03-2018 CU254_RS19510 e9f1eb0376132d80abad28a36fb11bf6 275 Pfam PF04951 D-aminopeptidase 1 260 1.6E-95 T 28-03-2018 IPR007035 Peptidase M55, D-aminopeptidase CU254_RS19510 e9f1eb0376132d80abad28a36fb11bf6 275 PIRSF PIRSF015853 1 272 7.0E-94 T 28-03-2018 IPR007035 Peptidase M55, D-aminopeptidase CU254_RS19510 e9f1eb0376132d80abad28a36fb11bf6 275 Gene3D G3DSA:3.40.50.10780 1 210 4.6E-82 T 28-03-2018 IPR027476 D-aminopeptidase, N-terminal CU254_RS32545 fd7a7dda32e3547ffde9470a1a44e3f9 304 SUPERFAMILY SSF161111 6 219 5.75E-40 T 28-03-2018 CU254_RS32545 fd7a7dda32e3547ffde9470a1a44e3f9 304 Gene3D G3DSA:1.20.1510.10 6 217 4.8E-37 T 28-03-2018 CU254_RS32545 fd7a7dda32e3547ffde9470a1a44e3f9 304 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 8 286 9.3E-41 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CU254_RS32545 fd7a7dda32e3547ffde9470a1a44e3f9 304 Pfam PF01545 Cation efflux family 10 211 1.6E-36 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CU254_RS32545 fd7a7dda32e3547ffde9470a1a44e3f9 304 Gene3D G3DSA:3.30.70.1350 218 304 1.8E-5 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CU254_RS04685 96a1b0fe00b75e631f5401c269fb6d6a 290 Gene3D G3DSA:1.10.10.60 223 280 6.8E-15 T 28-03-2018 CU254_RS04685 96a1b0fe00b75e631f5401c269fb6d6a 290 Pfam PF02311 AraC-like ligand binding domain 31 131 5.4E-7 T 28-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CU254_RS04685 96a1b0fe00b75e631f5401c269fb6d6a 290 SUPERFAMILY SSF46689 223 271 2.15E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS04685 96a1b0fe00b75e631f5401c269fb6d6a 290 SMART SM00342 186 269 1.6E-22 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS04685 96a1b0fe00b75e631f5401c269fb6d6a 290 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 253 269 1.2E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CU254_RS04685 96a1b0fe00b75e631f5401c269fb6d6a 290 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 238 253 1.2E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CU254_RS04685 96a1b0fe00b75e631f5401c269fb6d6a 290 SUPERFAMILY SSF51215 29 152 1.05E-13 T 28-03-2018 CU254_RS04685 96a1b0fe00b75e631f5401c269fb6d6a 290 Gene3D G3DSA:2.60.120.280 19 156 5.3E-20 T 28-03-2018 CU254_RS04685 96a1b0fe00b75e631f5401c269fb6d6a 290 Pfam PF12833 Helix-turn-helix domain 193 270 4.1E-20 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS21840 bbb4dc0a962716bbb922d29f7bbc009d 409 Pfam PF00561 alpha/beta hydrolase fold 48 186 1.1E-17 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS21840 bbb4dc0a962716bbb922d29f7bbc009d 409 SUPERFAMILY SSF53474 257 401 9.59E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS21840 bbb4dc0a962716bbb922d29f7bbc009d 409 SUPERFAMILY SSF53474 33 164 9.59E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS21840 bbb4dc0a962716bbb922d29f7bbc009d 409 Gene3D G3DSA:3.40.50.1820 9 406 2.6E-30 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS21840 bbb4dc0a962716bbb922d29f7bbc009d 409 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 49 57 3.5E-9 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CU254_RS21840 bbb4dc0a962716bbb922d29f7bbc009d 409 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 134 148 3.5E-9 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CU254_RS21840 bbb4dc0a962716bbb922d29f7bbc009d 409 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 80 91 3.5E-9 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CU254_RS14170 2597a0a7ddb3314367eb9161a09c5435 120 Gene3D G3DSA:3.10.180.10 1 119 7.3E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS14170 2597a0a7ddb3314367eb9161a09c5435 120 SUPERFAMILY SSF54593 1 116 1.09E-13 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS27825 d99d6cba21cc5f564ccf82b875231093 349 Pfam PF07724 AAA domain (Cdc48 subfamily) 71 244 5.2E-35 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CU254_RS27825 d99d6cba21cc5f564ccf82b875231093 349 SUPERFAMILY SSF52540 30 321 7.77E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS27825 d99d6cba21cc5f564ccf82b875231093 349 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 251 320 4.2E-17 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CU254_RS27825 d99d6cba21cc5f564ccf82b875231093 349 SMART SM00382 71 218 1.5E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS27825 d99d6cba21cc5f564ccf82b875231093 349 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 120 138 3.3E-25 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CU254_RS27825 d99d6cba21cc5f564ccf82b875231093 349 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 187 201 3.3E-25 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CU254_RS27825 d99d6cba21cc5f564ccf82b875231093 349 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 153 171 3.3E-25 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CU254_RS27825 d99d6cba21cc5f564ccf82b875231093 349 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 75 93 3.3E-25 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CU254_RS27825 d99d6cba21cc5f564ccf82b875231093 349 SMART SM01086 251 340 1.8E-16 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CU254_RS27825 d99d6cba21cc5f564ccf82b875231093 349 Gene3D G3DSA:1.10.8.60 251 346 9.9E-17 T 28-03-2018 CU254_RS27825 d99d6cba21cc5f564ccf82b875231093 349 Gene3D G3DSA:3.40.50.300 26 250 1.9E-36 T 28-03-2018 CU254_RS35480 f9dce7d3d8c10fdd07e251732bed7139 335 SUPERFAMILY SSF51695 23 197 9.42E-17 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CU254_RS35480 f9dce7d3d8c10fdd07e251732bed7139 335 SUPERFAMILY SSF51695 256 281 9.42E-17 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CU254_RS35480 f9dce7d3d8c10fdd07e251732bed7139 335 Gene3D G3DSA:3.20.20.190 19 214 4.8E-18 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CU254_RS35480 f9dce7d3d8c10fdd07e251732bed7139 335 Pfam PF16670 Phosphoinositide phospholipase C, Ca2+-dependent 93 189 1.5E-11 T 28-03-2018 IPR032075 Phosphoinositide phospholipase C, Ca2+-dependent CU254_RS07740 4c5657524bad0b45e54cd4e554c98c97 1200 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1191 22.176 T 28-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 CU254_RS07740 4c5657524bad0b45e54cd4e554c98c97 1200 SMART SM00968 512 626 1.9E-20 T 28-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CU254_RS07740 4c5657524bad0b45e54cd4e554c98c97 1200 PIRSF PIRSF005719 1 1197 7.1E-259 T 28-03-2018 IPR024704 Structural maintenance of chromosomes protein CU254_RS07740 4c5657524bad0b45e54cd4e554c98c97 1200 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 3 1189 3.0E-293 T 28-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 CU254_RS07740 4c5657524bad0b45e54cd4e554c98c97 1200 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 1182 6.4E-71 T 28-03-2018 IPR003395 RecF/RecN/SMC, N-terminal CU254_RS07740 4c5657524bad0b45e54cd4e554c98c97 1200 SUPERFAMILY SSF75553 467 671 1.01E-27 T 28-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CU254_RS07740 4c5657524bad0b45e54cd4e554c98c97 1200 Gene3D G3DSA:3.40.50.300 2 227 3.0E-40 T 28-03-2018 CU254_RS07740 4c5657524bad0b45e54cd4e554c98c97 1200 Pfam PF06470 SMC proteins Flexible Hinge Domain 512 626 5.5E-20 T 28-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CU254_RS07740 4c5657524bad0b45e54cd4e554c98c97 1200 Gene3D G3DSA:1.20.1170.10 388 771 1.3E-8 T 28-03-2018 CU254_RS07740 4c5657524bad0b45e54cd4e554c98c97 1200 Gene3D G3DSA:3.40.50.300 772 1194 5.1E-28 T 28-03-2018 CU254_RS07740 4c5657524bad0b45e54cd4e554c98c97 1200 SUPERFAMILY SSF52540 1075 1182 2.79E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS07740 4c5657524bad0b45e54cd4e554c98c97 1200 SUPERFAMILY SSF52540 2 166 2.79E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS11300 321e02bbdbf24f4698b41e092af3fab4 460 Gene3D G3DSA:3.40.50.300 21 174 7.3E-27 T 28-03-2018 CU254_RS11300 321e02bbdbf24f4698b41e092af3fab4 460 SMART SM00382 69 186 5.8E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS11300 321e02bbdbf24f4698b41e092af3fab4 460 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 73 177 9.1E-16 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CU254_RS11300 321e02bbdbf24f4698b41e092af3fab4 460 SUPERFAMILY SSF52540 33 253 5.4E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS11300 321e02bbdbf24f4698b41e092af3fab4 460 Pfam PF12002 MgsA AAA+ ATPase C terminal 285 450 6.6E-70 T 28-03-2018 IPR021886 MgsA AAA+ ATPase C-terminal CU254_RS11300 321e02bbdbf24f4698b41e092af3fab4 460 SUPERFAMILY SSF48019 270 453 7.94E-75 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CU254_RS11300 321e02bbdbf24f4698b41e092af3fab4 460 Pfam PF16193 AAA C-terminal domain 208 284 3.8E-29 T 28-03-2018 IPR032423 AAA C-terminal domain CU254_RS11300 321e02bbdbf24f4698b41e092af3fab4 460 Gene3D G3DSA:1.10.3710.10 366 460 5.8E-29 T 28-03-2018 CU254_RS11300 321e02bbdbf24f4698b41e092af3fab4 460 Gene3D G3DSA:1.10.8.60 175 260 4.9E-21 T 28-03-2018 CU254_RS11300 321e02bbdbf24f4698b41e092af3fab4 460 Gene3D G3DSA:1.20.272.10 269 363 3.3E-41 T 28-03-2018 CU254_RS16195 477d1431023b1f24cf2f01c61dcf3af2 88 SUPERFAMILY SSF50118 1 70 2.09E-20 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CU254_RS16195 477d1431023b1f24cf2f01c61dcf3af2 88 Pfam PF08940 Domain of unknown function (DUF1918) 1 58 1.5E-19 T 28-03-2018 IPR015035 Domain of unknown function DUF1918 CU254_RS22970 474a68e5d59c5b1422361fb9bdfaa10f 603 Gene3D G3DSA:2.60.40.1180 507 603 1.5E-14 T 28-03-2018 CU254_RS22970 474a68e5d59c5b1422361fb9bdfaa10f 603 SMART SM00812 123 551 5.7E-133 T 28-03-2018 IPR000933 Glycoside hydrolase, family 29 GO:0004560|GO:0005975 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CU254_RS22970 474a68e5d59c5b1422361fb9bdfaa10f 603 PRINTS PR00741 Glycosyl hydrolase family 29 signature 240 256 1.1E-5 T 28-03-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CU254_RS22970 474a68e5d59c5b1422361fb9bdfaa10f 603 PRINTS PR00741 Glycosyl hydrolase family 29 signature 286 305 1.1E-5 T 28-03-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CU254_RS22970 474a68e5d59c5b1422361fb9bdfaa10f 603 Pfam PF01120 Alpha-L-fucosidase 117 505 3.2E-93 T 28-03-2018 IPR000933 Glycoside hydrolase, family 29 GO:0004560|GO:0005975 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CU254_RS22970 474a68e5d59c5b1422361fb9bdfaa10f 603 Gene3D G3DSA:3.20.20.80 119 506 1.9E-101 T 28-03-2018 CU254_RS22970 474a68e5d59c5b1422361fb9bdfaa10f 603 PIRSF PIRSF001092 105 598 6.4E-106 T 28-03-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CU254_RS22970 474a68e5d59c5b1422361fb9bdfaa10f 603 SUPERFAMILY SSF51445 341 508 2.11E-99 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS22970 474a68e5d59c5b1422361fb9bdfaa10f 603 SUPERFAMILY SSF51445 123 313 2.11E-99 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS22970 474a68e5d59c5b1422361fb9bdfaa10f 603 Pfam PF16757 Alpha-L-fucosidase C-terminal domain 522 600 4.4E-6 T 28-03-2018 IPR031919 Alpha-L-fucosidase, C-terminal KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CU254_RS11975 b281741f095292d3b3c8394b301e08f4 52 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 4 45 1.1E-10 T 28-03-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CU254_RS11975 b281741f095292d3b3c8394b301e08f4 52 SUPERFAMILY SSF51726 3 50 5.62E-10 T 28-03-2018 CU254_RS11975 b281741f095292d3b3c8394b301e08f4 52 Gene3D G3DSA:3.20.20.210 1 51 7.9E-13 T 28-03-2018 CU254_RS22810 0eaecd216d425ceb767f081ed9737a9c 426 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 320 412 9.1E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS22810 0eaecd216d425ceb767f081ed9737a9c 426 Gene3D G3DSA:1.20.1170.10 35 289 6.2E-4 T 28-03-2018 CU254_RS22810 0eaecd216d425ceb767f081ed9737a9c 426 SUPERFAMILY SSF55874 281 412 9.58E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS22810 0eaecd216d425ceb767f081ed9737a9c 426 PIRSF PIRSF037434 5 419 2.0E-77 T 28-03-2018 IPR017205 Signal transduction histidine kinase, ChrS CU254_RS22810 0eaecd216d425ceb767f081ed9737a9c 426 Gene3D G3DSA:3.30.565.10 290 420 5.3E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS22810 0eaecd216d425ceb767f081ed9737a9c 426 SMART SM00387 317 415 0.0036 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS22810 0eaecd216d425ceb767f081ed9737a9c 426 Pfam PF07730 Histidine kinase 213 278 7.5E-15 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CU254_RS29765 b8ba78d3877da6084aa01d9f164199f8 251 Gene3D G3DSA:3.40.50.410 75 210 5.5E-20 T 28-03-2018 IPR002035 von Willebrand factor, type A CU254_RS29765 b8ba78d3877da6084aa01d9f164199f8 251 SMART SM00327 88 246 8.4E-10 T 28-03-2018 IPR002035 von Willebrand factor, type A CU254_RS29765 b8ba78d3877da6084aa01d9f164199f8 251 SUPERFAMILY SSF53300 87 208 1.0E-19 T 28-03-2018 IPR002035 von Willebrand factor, type A CU254_RS29765 b8ba78d3877da6084aa01d9f164199f8 251 Pfam PF05762 VWA domain containing CoxE-like protein 43 216 6.7E-13 T 28-03-2018 IPR008912 Uncharacterised protein family CoxE-like CU254_RS01225 ce2050487534ef7e9022116250406db5 534 Pfam PF05140 ResB-like family 36 521 4.7E-129 T 28-03-2018 IPR007816 ResB-like domain CU254_RS36980 6c011575613d087eb146d1588f409dc1 301 Pfam PF03466 LysR substrate binding domain 87 296 1.5E-32 T 28-03-2018 IPR005119 LysR, substrate-binding CU254_RS36980 6c011575613d087eb146d1588f409dc1 301 Gene3D G3DSA:3.40.190.10 88 183 2.3E-15 T 28-03-2018 CU254_RS36980 6c011575613d087eb146d1588f409dc1 301 Gene3D G3DSA:3.40.190.10 184 268 7.4E-20 T 28-03-2018 CU254_RS36980 6c011575613d087eb146d1588f409dc1 301 SUPERFAMILY SSF46785 1 111 2.02E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS36980 6c011575613d087eb146d1588f409dc1 301 Gene3D G3DSA:1.10.10.10 1 83 5.2E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS36980 6c011575613d087eb146d1588f409dc1 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 6.9E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS36980 6c011575613d087eb146d1588f409dc1 301 SUPERFAMILY SSF53850 89 299 9.41E-30 T 28-03-2018 CU254_RS16460 e17ed74982742ef58fe3715a90f3a6b4 298 Pfam PF00005 ABC transporter 2 156 8.5E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS16460 e17ed74982742ef58fe3715a90f3a6b4 298 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS16460 e17ed74982742ef58fe3715a90f3a6b4 298 SMART SM00382 7 214 1.9E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS16460 e17ed74982742ef58fe3715a90f3a6b4 298 Gene3D G3DSA:3.40.50.300 1 298 9.0E-66 T 28-03-2018 CU254_RS16460 e17ed74982742ef58fe3715a90f3a6b4 298 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 208 269 8.0E-17 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CU254_RS16460 e17ed74982742ef58fe3715a90f3a6b4 298 SUPERFAMILY SSF52540 7 271 1.13E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS16460 e17ed74982742ef58fe3715a90f3a6b4 298 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 208 294 2.8E-21 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CU254_RS21480 2de60afca9d684255575da299c807bde 198 Gene3D G3DSA:1.10.150.20 66 135 2.9E-14 T 28-03-2018 CU254_RS21480 2de60afca9d684255575da299c807bde 198 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 191 7.9E-40 T 28-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 CU254_RS21480 2de60afca9d684255575da299c807bde 198 Gene3D G3DSA:1.10.8.10 139 198 7.5E-17 T 28-03-2018 CU254_RS21480 2de60afca9d684255575da299c807bde 198 SUPERFAMILY SSF50249 1 62 1.26E-13 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CU254_RS21480 2de60afca9d684255575da299c807bde 198 Pfam PF01330 RuvA N terminal domain 1 61 3.3E-19 T 28-03-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 CU254_RS21480 2de60afca9d684255575da299c807bde 198 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 195 28.473 T 28-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 CU254_RS21480 2de60afca9d684255575da299c807bde 198 Pfam PF07499 RuvA, C-terminal domain 149 194 1.8E-13 T 28-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 CU254_RS21480 2de60afca9d684255575da299c807bde 198 Pfam PF14520 Helix-hairpin-helix domain 71 129 3.4E-13 T 28-03-2018 CU254_RS21480 2de60afca9d684255575da299c807bde 198 SUPERFAMILY SSF47781 65 133 4.36E-18 T 28-03-2018 IPR010994 RuvA domain 2-like CU254_RS21480 2de60afca9d684255575da299c807bde 198 SUPERFAMILY SSF46929 149 197 4.84E-10 T 28-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 CU254_RS21480 2de60afca9d684255575da299c807bde 198 Gene3D G3DSA:2.40.50.140 1 62 1.1E-22 T 28-03-2018 CU254_RS28035 525116342f6c8822feeed4ba91d350ef 461 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 342 450 9.9E-34 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CU254_RS28035 525116342f6c8822feeed4ba91d350ef 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 136 145 1.6E-61 T 28-03-2018 CU254_RS28035 525116342f6c8822feeed4ba91d350ef 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 302 309 1.6E-61 T 28-03-2018 CU254_RS28035 525116342f6c8822feeed4ba91d350ef 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 1.6E-61 T 28-03-2018 CU254_RS28035 525116342f6c8822feeed4ba91d350ef 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 338 359 1.6E-61 T 28-03-2018 CU254_RS28035 525116342f6c8822feeed4ba91d350ef 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 171 196 1.6E-61 T 28-03-2018 CU254_RS28035 525116342f6c8822feeed4ba91d350ef 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 425 445 1.6E-61 T 28-03-2018 CU254_RS28035 525116342f6c8822feeed4ba91d350ef 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 259 273 1.6E-61 T 28-03-2018 CU254_RS28035 525116342f6c8822feeed4ba91d350ef 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 403 418 1.6E-61 T 28-03-2018 CU254_RS28035 525116342f6c8822feeed4ba91d350ef 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 1.6E-61 T 28-03-2018 CU254_RS28035 525116342f6c8822feeed4ba91d350ef 461 Gene3D G3DSA:3.40.50.720 2 37 0.088 T 28-03-2018 CU254_RS28035 525116342f6c8822feeed4ba91d350ef 461 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 28-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CU254_RS28035 525116342f6c8822feeed4ba91d350ef 461 SUPERFAMILY SSF51905 2 331 3.89E-61 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS28035 525116342f6c8822feeed4ba91d350ef 461 Gene3D G3DSA:1.10.287.990 38 106 6.6E-18 T 28-03-2018 CU254_RS28035 525116342f6c8822feeed4ba91d350ef 461 PIRSF PIRSF000350 1 457 2.2E-79 T 28-03-2018 CU254_RS28035 525116342f6c8822feeed4ba91d350ef 461 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 322 2.2E-66 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS28035 525116342f6c8822feeed4ba91d350ef 461 Gene3D G3DSA:3.40.50.720 144 329 1.2E-36 T 28-03-2018 CU254_RS28035 525116342f6c8822feeed4ba91d350ef 461 SUPERFAMILY SSF55424 338 460 1.01E-36 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CU254_RS28035 525116342f6c8822feeed4ba91d350ef 461 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 5 460 2.7E-163 T 28-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 CU254_RS28035 525116342f6c8822feeed4ba91d350ef 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 274 6.4E-33 T 28-03-2018 CU254_RS28035 525116342f6c8822feeed4ba91d350ef 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 133 151 6.4E-33 T 28-03-2018 CU254_RS28035 525116342f6c8822feeed4ba91d350ef 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 287 309 6.4E-33 T 28-03-2018 CU254_RS28035 525116342f6c8822feeed4ba91d350ef 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 171 189 6.4E-33 T 28-03-2018 CU254_RS28035 525116342f6c8822feeed4ba91d350ef 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 6.4E-33 T 28-03-2018 CU254_RS28035 525116342f6c8822feeed4ba91d350ef 461 Gene3D G3DSA:3.30.390.30 330 457 3.0E-36 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CU254_RS04620 4ba016ed869ffe83c3c3c2cedf8855de 182 Pfam PF04965 Gene 25-like lysozyme 85 169 1.3E-15 T 28-03-2018 IPR007048 GpW/Gp25/anti-adapter protein IraD CU254_RS04620 4ba016ed869ffe83c3c3c2cedf8855de 182 Gene3D G3DSA:3.10.450.40 55 177 5.2E-27 T 28-03-2018 CU254_RS04620 4ba016ed869ffe83c3c3c2cedf8855de 182 SUPERFAMILY SSF160719 80 176 5.23E-21 T 28-03-2018 CU254_RS12125 c29f6eb981e7368714e65caebe3e65f9 221 Gene3D G3DSA:3.40.50.1000 73 219 4.8E-32 T 28-03-2018 IPR023214 HAD-like domain CU254_RS12125 c29f6eb981e7368714e65caebe3e65f9 221 Pfam PF13419 Haloacid dehalogenase-like hydrolase 9 186 1.6E-25 T 28-03-2018 IPR023214 HAD-like domain CU254_RS12125 c29f6eb981e7368714e65caebe3e65f9 221 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 67 180 1.7E-11 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CU254_RS12125 c29f6eb981e7368714e65caebe3e65f9 221 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 77 186 1.3E-11 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CU254_RS12125 c29f6eb981e7368714e65caebe3e65f9 221 Gene3D G3DSA:1.10.150.240 21 72 2.9E-17 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CU254_RS12125 c29f6eb981e7368714e65caebe3e65f9 221 SUPERFAMILY SSF56784 7 217 4.07E-48 T 28-03-2018 IPR023214 HAD-like domain CU254_RS09775 dbe22818aee8a83921b53b8fd844cec9 319 SUPERFAMILY SSF50129 1 140 4.15E-14 T 28-03-2018 IPR011032 GroES-like CU254_RS09775 dbe22818aee8a83921b53b8fd844cec9 319 Gene3D G3DSA:3.90.180.10 69 126 2.2E-6 T 28-03-2018 CU254_RS09775 dbe22818aee8a83921b53b8fd844cec9 319 SMART SM00829 11 317 0.0017 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CU254_RS09775 dbe22818aee8a83921b53b8fd844cec9 319 Gene3D G3DSA:3.40.50.720 127 264 2.2E-21 T 28-03-2018 CU254_RS09775 dbe22818aee8a83921b53b8fd844cec9 319 Pfam PF00107 Zinc-binding dehydrogenase 146 281 1.2E-7 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CU254_RS09775 dbe22818aee8a83921b53b8fd844cec9 319 SUPERFAMILY SSF51735 107 287 5.25E-21 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS09775 dbe22818aee8a83921b53b8fd844cec9 319 Gene3D G3DSA:3.90.180.10 1 68 8.7E-7 T 28-03-2018 CU254_RS01815 9221236178d4c6c8396624aad8ac7db3 157 Pfam PF01817 Chorismate mutase type II 5 76 1.2E-8 T 28-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CU254_RS01815 9221236178d4c6c8396624aad8ac7db3 157 Gene3D G3DSA:1.20.59.10 3 84 9.3E-17 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CU254_RS01815 9221236178d4c6c8396624aad8ac7db3 157 SMART SM00830 3 78 2.5E-11 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CU254_RS01815 9221236178d4c6c8396624aad8ac7db3 157 TIGRFAM TIGR01806 CM_mono2: putative chorismate mutase 8 113 1.0E-23 T 28-03-2018 IPR008240 Chorismate mutase, periplasmic KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CU254_RS01815 9221236178d4c6c8396624aad8ac7db3 157 SUPERFAMILY SSF48600 4 117 7.48E-25 T 28-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CU254_RS26830 8b347d4652373b43821cdebe229c09da 507 ProSitePatterns PS00905 GTP1/OBG family signature. 213 226 - T 28-03-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 CU254_RS26830 8b347d4652373b43821cdebe229c09da 507 Hamap MF_01454 GTPase Obg [obg]. 4 336 44.503 T 28-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 CU254_RS26830 8b347d4652373b43821cdebe229c09da 507 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 228 246 1.1E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CU254_RS26830 8b347d4652373b43821cdebe229c09da 507 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 211 226 1.1E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CU254_RS26830 8b347d4652373b43821cdebe229c09da 507 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 163 183 1.1E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CU254_RS26830 8b347d4652373b43821cdebe229c09da 507 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 184 202 1.1E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CU254_RS26830 8b347d4652373b43821cdebe229c09da 507 SUPERFAMILY SSF52540 152 346 6.27E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS26830 8b347d4652373b43821cdebe229c09da 507 Gene3D G3DSA:2.70.210.12 4 157 3.1E-53 T 28-03-2018 IPR006169 GTP1/OBG domain CU254_RS26830 8b347d4652373b43821cdebe229c09da 507 Pfam PF09269 Domain of unknown function (DUF1967) 362 432 3.3E-26 T 28-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 CU254_RS26830 8b347d4652373b43821cdebe229c09da 507 Pfam PF01926 50S ribosome-binding GTPase 162 289 7.2E-22 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CU254_RS26830 8b347d4652373b43821cdebe229c09da 507 SUPERFAMILY SSF82051 5 158 4.58E-48 T 28-03-2018 IPR006169 GTP1/OBG domain CU254_RS26830 8b347d4652373b43821cdebe229c09da 507 Pfam PF01018 GTP1/OBG 6 158 2.2E-52 T 28-03-2018 IPR006169 GTP1/OBG domain CU254_RS26830 8b347d4652373b43821cdebe229c09da 507 Gene3D G3DSA:3.40.50.300 160 344 3.6E-30 T 28-03-2018 CU254_RS26830 8b347d4652373b43821cdebe229c09da 507 TIGRFAM TIGR03595 Obg_CgtA_exten: Obg family GTPase CgtA, C-terminal extension 363 433 1.7E-25 T 28-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 CU254_RS26830 8b347d4652373b43821cdebe229c09da 507 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 5 335 2.0E-124 T 28-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 CU254_RS26830 8b347d4652373b43821cdebe229c09da 507 SUPERFAMILY SSF102741 361 434 8.37E-21 T 28-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 CU254_RS22675 045fd0d351046abb0e3496f135086065 879 Gene3D G3DSA:2.60.40.10 656 777 6.8E-37 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS22675 045fd0d351046abb0e3496f135086065 879 SUPERFAMILY SSF49785 48 200 7.9E-32 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS22675 045fd0d351046abb0e3496f135086065 879 Gene3D G3DSA:2.60.120.260 37 201 1.1E-29 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS22675 045fd0d351046abb0e3496f135086065 879 Pfam PF00703 Glycosyl hydrolases family 2 209 316 3.9E-7 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 CU254_RS22675 045fd0d351046abb0e3496f135086065 879 SUPERFAMILY SSF49303 656 757 1.01E-24 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 CU254_RS22675 045fd0d351046abb0e3496f135086065 879 SUPERFAMILY SSF49303 207 316 5.04E-21 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 CU254_RS22675 045fd0d351046abb0e3496f135086065 879 Gene3D G3DSA:3.20.20.80 317 655 5.2E-61 T 28-03-2018 CU254_RS22675 045fd0d351046abb0e3496f135086065 879 SUPERFAMILY SSF49303 760 877 1.84E-35 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 CU254_RS22675 045fd0d351046abb0e3496f135086065 879 Gene3D G3DSA:2.60.40.10 781 879 8.0E-30 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS22675 045fd0d351046abb0e3496f135086065 879 SUPERFAMILY SSF51445 313 654 5.63E-77 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS22675 045fd0d351046abb0e3496f135086065 879 Gene3D G3DSA:2.60.40.10 202 314 4.5E-15 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS20095 69f486cdd72c356360081e7a32780709 276 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 269 9.3E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS20095 69f486cdd72c356360081e7a32780709 276 SUPERFAMILY SSF161098 2 276 1.31E-76 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS20095 69f486cdd72c356360081e7a32780709 276 Gene3D G3DSA:1.10.3720.10 1 263 2.2E-50 T 28-03-2018 CU254_RS35035 ec0936a4086a7235e7a4d5bfceb3dfc2 374 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 7 373 24.407 T 28-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 CU254_RS35035 ec0936a4086a7235e7a4d5bfceb3dfc2 374 PIRSF PIRSF000525 4 374 2.5E-77 T 28-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 CU254_RS35035 ec0936a4086a7235e7a4d5bfceb3dfc2 374 Gene3D G3DSA:3.40.640.10 23 261 8.7E-20 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS35035 ec0936a4086a7235e7a4d5bfceb3dfc2 374 SUPERFAMILY SSF53383 14 372 6.77E-75 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS35035 ec0936a4086a7235e7a4d5bfceb3dfc2 374 TIGRFAM TIGR01366 serC_3: putative phosphoserine aminotransferase 13 373 4.0E-193 T 28-03-2018 IPR006272 Phosphoserine aminotransferase, Mycobacterial-type GO:0004648|GO:0006564|GO:0009058 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52 CU254_RS35035 ec0936a4086a7235e7a4d5bfceb3dfc2 374 Pfam PF00266 Aminotransferase class-V 38 332 7.7E-15 T 28-03-2018 IPR000192 Aminotransferase class V domain CU254_RS35035 ec0936a4086a7235e7a4d5bfceb3dfc2 374 Gene3D G3DSA:3.90.1150.10 262 373 2.2E-23 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS34900 b129d3b095e1f3cf0e649b21b5d0a0c5 401 Gene3D G3DSA:3.40.640.10 48 292 2.0E-40 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS34900 b129d3b095e1f3cf0e649b21b5d0a0c5 401 Pfam PF00266 Aminotransferase class-V 75 389 2.6E-41 T 28-03-2018 IPR000192 Aminotransferase class V domain CU254_RS34900 b129d3b095e1f3cf0e649b21b5d0a0c5 401 Gene3D G3DSA:3.90.1150.10 293 397 2.1E-12 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS34900 b129d3b095e1f3cf0e649b21b5d0a0c5 401 SUPERFAMILY SSF53383 29 397 1.44E-75 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS35685 8df8e521d7b3f0b44090f5e6c931f2bb 520 Pfam PF00501 AMP-binding enzyme 17 415 1.1E-88 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS35685 8df8e521d7b3f0b44090f5e6c931f2bb 520 TIGRFAM TIGR02262 benz_CoA_lig: benzoate-CoA ligase family 6 508 2.7E-152 T 28-03-2018 IPR011957 Benzoate-CoA ligase family GO:0005524|GO:0016405 CU254_RS35685 8df8e521d7b3f0b44090f5e6c931f2bb 520 Gene3D G3DSA:3.40.50.980 11 174 9.8E-35 T 28-03-2018 CU254_RS35685 8df8e521d7b3f0b44090f5e6c931f2bb 520 Gene3D G3DSA:3.30.300.30 410 515 7.9E-28 T 28-03-2018 CU254_RS35685 8df8e521d7b3f0b44090f5e6c931f2bb 520 SUPERFAMILY SSF56801 17 511 1.18E-136 T 28-03-2018 CU254_RS35685 8df8e521d7b3f0b44090f5e6c931f2bb 520 Gene3D G3DSA:3.40.50.980 175 324 5.5E-41 T 28-03-2018 CU254_RS35685 8df8e521d7b3f0b44090f5e6c931f2bb 520 Pfam PF13193 AMP-binding enzyme C-terminal domain 424 499 1.4E-17 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS35685 8df8e521d7b3f0b44090f5e6c931f2bb 520 Gene3D G3DSA:2.30.38.10 325 408 6.0E-21 T 28-03-2018 CU254_RS00715 6cf89926dfcb16caf933d928984a17c2 390 Pfam PF01494 FAD binding domain 2 341 9.0E-73 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CU254_RS00715 6cf89926dfcb16caf933d928984a17c2 390 Gene3D G3DSA:3.30.9.10 318 387 3.6E-17 T 28-03-2018 CU254_RS00715 6cf89926dfcb16caf933d928984a17c2 390 Gene3D G3DSA:3.30.9.10 169 284 1.1E-49 T 28-03-2018 CU254_RS00715 6cf89926dfcb16caf933d928984a17c2 390 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 151 166 5.9E-27 T 28-03-2018 CU254_RS00715 6cf89926dfcb16caf933d928984a17c2 390 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 5.9E-27 T 28-03-2018 CU254_RS00715 6cf89926dfcb16caf933d928984a17c2 390 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 293 309 5.9E-27 T 28-03-2018 CU254_RS00715 6cf89926dfcb16caf933d928984a17c2 390 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 278 293 5.9E-27 T 28-03-2018 CU254_RS00715 6cf89926dfcb16caf933d928984a17c2 390 SUPERFAMILY SSF51905 265 369 9.13E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS00715 6cf89926dfcb16caf933d928984a17c2 390 SUPERFAMILY SSF51905 3 172 9.13E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS00715 6cf89926dfcb16caf933d928984a17c2 390 SUPERFAMILY SSF54373 175 275 8.24E-41 T 28-03-2018 CU254_RS00715 6cf89926dfcb16caf933d928984a17c2 390 Gene3D G3DSA:3.50.50.60 3 168 1.9E-15 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS31465 bc65e6a5f471fd4d5a661fb20c07279f 138 PRINTS PR00598 Bacterial regulatory protein MarR family signature 41 57 1.7E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS31465 bc65e6a5f471fd4d5a661fb20c07279f 138 PRINTS PR00598 Bacterial regulatory protein MarR family signature 77 93 1.7E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS31465 bc65e6a5f471fd4d5a661fb20c07279f 138 PRINTS PR00598 Bacterial regulatory protein MarR family signature 108 128 1.7E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS31465 bc65e6a5f471fd4d5a661fb20c07279f 138 PRINTS PR00598 Bacterial regulatory protein MarR family signature 58 73 1.7E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS31465 bc65e6a5f471fd4d5a661fb20c07279f 138 Gene3D G3DSA:1.10.10.10 1 138 1.8E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS31465 bc65e6a5f471fd4d5a661fb20c07279f 138 Pfam PF12802 MarR family 23 80 1.1E-13 T 28-03-2018 CU254_RS31465 bc65e6a5f471fd4d5a661fb20c07279f 138 SUPERFAMILY SSF46785 4 130 1.57E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS31465 bc65e6a5f471fd4d5a661fb20c07279f 138 SMART SM00347 14 118 9.8E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS18510 1fe48eaec894560459d3b8a069add963 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 59 1.3E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS18510 1fe48eaec894560459d3b8a069add963 196 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 81 194 4.3E-13 T 28-03-2018 CU254_RS18510 1fe48eaec894560459d3b8a069add963 196 SUPERFAMILY SSF48498 80 194 1.95E-14 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS18510 1fe48eaec894560459d3b8a069add963 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 1.3E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS18510 1fe48eaec894560459d3b8a069add963 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 1.3E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS18510 1fe48eaec894560459d3b8a069add963 196 Gene3D G3DSA:1.10.357.10 66 194 2.8E-14 T 28-03-2018 CU254_RS18510 1fe48eaec894560459d3b8a069add963 196 Gene3D G3DSA:1.10.10.60 8 43 1.1E-13 T 28-03-2018 CU254_RS18510 1fe48eaec894560459d3b8a069add963 196 SUPERFAMILY SSF46689 2 82 8.21E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS18510 1fe48eaec894560459d3b8a069add963 196 Gene3D G3DSA:1.10.260.40 44 65 1.9E-5 T 28-03-2018 CU254_RS27955 2ad46307ef5020a055ecec920167294e 321 Gene3D G3DSA:1.10.10.10 255 316 0.004 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS27955 2ad46307ef5020a055ecec920167294e 321 Pfam PF13556 PucR C-terminal helix-turn-helix domain 268 313 2.5E-11 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CU254_RS07495 82ae18a8dc7c42cebd86e795b8cf4511 238 SMART SM00895 92 214 5.1E-21 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS07495 82ae18a8dc7c42cebd86e795b8cf4511 238 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 66 2.4E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS07495 82ae18a8dc7c42cebd86e795b8cf4511 238 SUPERFAMILY SSF46785 1 70 1.51E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS07495 82ae18a8dc7c42cebd86e795b8cf4511 238 SUPERFAMILY SSF48008 89 221 2.14E-27 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS07495 82ae18a8dc7c42cebd86e795b8cf4511 238 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 56 8.5E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS07495 82ae18a8dc7c42cebd86e795b8cf4511 238 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 26 40 8.5E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS07495 82ae18a8dc7c42cebd86e795b8cf4511 238 Gene3D G3DSA:1.20.120.530 72 231 2.3E-31 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS07495 82ae18a8dc7c42cebd86e795b8cf4511 238 Pfam PF07729 FCD domain 92 213 8.1E-25 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS07495 82ae18a8dc7c42cebd86e795b8cf4511 238 Gene3D G3DSA:1.10.10.10 1 68 3.7E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS07495 82ae18a8dc7c42cebd86e795b8cf4511 238 SMART SM00345 7 66 6.4E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS37030 76cc5a6ccf534159d8285551b88ca747 333 SUPERFAMILY SSF161098 92 159 5.1E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS37030 76cc5a6ccf534159d8285551b88ca747 333 SUPERFAMILY SSF161098 195 317 5.1E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS37030 76cc5a6ccf534159d8285551b88ca747 333 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 331 1.6E-36 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS37030 76cc5a6ccf534159d8285551b88ca747 333 Gene3D G3DSA:1.10.3720.10 2 320 2.0E-40 T 28-03-2018 CU254_RS36230 f6fefc5e501ad0eb59a59a5e2162d974 189 TIGRFAM TIGR03086 TIGR03086: TIGR03086 family protein 11 185 8.9E-39 T 28-03-2018 IPR017520 Conserved hypothetical protein CHP03086 CU254_RS36230 f6fefc5e501ad0eb59a59a5e2162d974 189 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 8 185 1.5E-18 T 28-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CU254_RS36230 f6fefc5e501ad0eb59a59a5e2162d974 189 Gene3D G3DSA:1.20.120.450 1 135 2.0E-14 T 28-03-2018 CU254_RS36230 f6fefc5e501ad0eb59a59a5e2162d974 189 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 9 128 1.2E-9 T 28-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CU254_RS36230 f6fefc5e501ad0eb59a59a5e2162d974 189 SUPERFAMILY SSF109854 5 134 2.01E-14 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CU254_RS34785 563a13cd97467e4574aa785ab13fb1fa 80 Pfam PF01381 Helix-turn-helix 19 68 5.5E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS34785 563a13cd97467e4574aa785ab13fb1fa 80 SUPERFAMILY SSF47413 12 74 2.22E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS34785 563a13cd97467e4574aa785ab13fb1fa 80 Gene3D G3DSA:1.10.260.40 11 75 3.9E-16 T 28-03-2018 CU254_RS34785 563a13cd97467e4574aa785ab13fb1fa 80 SMART SM00530 15 70 3.5E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS01025 526df5df736035986f418e6106af1c72 249 PIRSF PIRSF000709 140 220 0.066 T 28-03-2018 CU254_RS01025 526df5df736035986f418e6106af1c72 249 PIRSF PIRSF000709 4 113 4.6E-4 T 28-03-2018 CU254_RS01025 526df5df736035986f418e6106af1c72 249 SMART SM00855 6 191 3.1E-24 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CU254_RS01025 526df5df736035986f418e6106af1c72 249 SUPERFAMILY SSF53254 6 225 1.21E-71 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CU254_RS01025 526df5df736035986f418e6106af1c72 249 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 9 18 - T 28-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 CU254_RS01025 526df5df736035986f418e6106af1c72 249 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 6 249 7.4E-111 T 28-03-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 CU254_RS01025 526df5df736035986f418e6106af1c72 249 Gene3D G3DSA:3.40.50.1240 3 249 3.0E-62 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CU254_RS01025 526df5df736035986f418e6106af1c72 249 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 4 232 42.649 T 28-03-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 CU254_RS01025 526df5df736035986f418e6106af1c72 249 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 7 209 3.2E-32 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CU254_RS25535 8498171699341854932ab3a2c7df32ae 226 Gene3D G3DSA:1.10.10.10 2 71 4.4E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS25535 8498171699341854932ab3a2c7df32ae 226 SUPERFAMILY SSF48008 75 216 6.28E-19 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS25535 8498171699341854932ab3a2c7df32ae 226 SUPERFAMILY SSF46785 3 73 7.93E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS25535 8498171699341854932ab3a2c7df32ae 226 Gene3D G3DSA:1.20.120.530 72 225 5.4E-30 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS25535 8498171699341854932ab3a2c7df32ae 226 Pfam PF07729 FCD domain 79 209 3.5E-19 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS25535 8498171699341854932ab3a2c7df32ae 226 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 69 3.7E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS25535 8498171699341854932ab3a2c7df32ae 226 SMART SM00895 79 210 5.5E-14 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS25535 8498171699341854932ab3a2c7df32ae 226 SMART SM00345 11 69 2.9E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS12035 c562e3963733173bdd29faf7cda65ff4 388 SUPERFAMILY SSF56645 4 244 4.97E-60 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS12035 c562e3963733173bdd29faf7cda65ff4 388 SUPERFAMILY SSF47203 229 386 4.03E-39 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS12035 c562e3963733173bdd29faf7cda65ff4 388 Gene3D G3DSA:1.10.540.10 1 121 3.8E-26 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS12035 c562e3963733173bdd29faf7cda65ff4 388 Gene3D G3DSA:1.20.140.10 222 388 2.6E-38 T 28-03-2018 CU254_RS12035 c562e3963733173bdd29faf7cda65ff4 388 PIRSF PIRSF016578 238 387 2.0E-7 T 28-03-2018 CU254_RS12035 c562e3963733173bdd29faf7cda65ff4 388 PIRSF PIRSF016578 2 197 2.2E-8 T 28-03-2018 CU254_RS12035 c562e3963733173bdd29faf7cda65ff4 388 Gene3D G3DSA:2.40.110.10 124 221 4.1E-28 T 28-03-2018 CU254_RS12035 c562e3963733173bdd29faf7cda65ff4 388 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 10 119 1.9E-23 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS12035 c562e3963733173bdd29faf7cda65ff4 388 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 239 379 1.4E-30 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS12035 c562e3963733173bdd29faf7cda65ff4 388 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 204 1.2E-18 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CU254_RS37795 b05c08303bcb4f5dbcf39f2717613e5a 382 SUPERFAMILY SSF54826 2 112 1.69E-28 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CU254_RS37795 b05c08303bcb4f5dbcf39f2717613e5a 382 SMART SM00922 125 231 3.4E-13 T 28-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CU254_RS37795 b05c08303bcb4f5dbcf39f2717613e5a 382 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 15 107 5.7E-23 T 28-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CU254_RS37795 b05c08303bcb4f5dbcf39f2717613e5a 382 Pfam PF13378 Enolase C-terminal domain-like 133 355 6.5E-60 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CU254_RS37795 b05c08303bcb4f5dbcf39f2717613e5a 382 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 180 211 - T 28-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 CU254_RS37795 b05c08303bcb4f5dbcf39f2717613e5a 382 Gene3D G3DSA:3.30.390.10 7 113 6.9E-34 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CU254_RS37795 b05c08303bcb4f5dbcf39f2717613e5a 382 Gene3D G3DSA:3.20.20.120 114 374 5.8E-63 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CU254_RS37795 b05c08303bcb4f5dbcf39f2717613e5a 382 SUPERFAMILY SSF51604 95 359 4.35E-70 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CU254_RS39175 206bbbf2da0e0c594acea6582ccedd60 382 SUPERFAMILY SSF47090 81 148 2.41E-19 T 28-03-2018 IPR002477 Peptidoglycan binding-like CU254_RS39175 206bbbf2da0e0c594acea6582ccedd60 382 SUPERFAMILY SSF53187 177 356 2.51E-42 T 28-03-2018 CU254_RS39175 206bbbf2da0e0c594acea6582ccedd60 382 Pfam PF01471 Putative peptidoglycan binding domain 10 69 3.2E-10 T 28-03-2018 IPR002477 Peptidoglycan binding-like CU254_RS39175 206bbbf2da0e0c594acea6582ccedd60 382 Pfam PF01471 Putative peptidoglycan binding domain 91 144 5.3E-17 T 28-03-2018 IPR002477 Peptidoglycan binding-like CU254_RS39175 206bbbf2da0e0c594acea6582ccedd60 382 SMART SM00646 238 353 6.6E-27 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CU254_RS39175 206bbbf2da0e0c594acea6582ccedd60 382 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 180 353 2.2E-36 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CU254_RS39175 206bbbf2da0e0c594acea6582ccedd60 382 Gene3D G3DSA:1.10.101.10 80 151 4.5E-21 T 28-03-2018 IPR002477 Peptidoglycan binding-like CU254_RS39175 206bbbf2da0e0c594acea6582ccedd60 382 SUPERFAMILY SSF47090 2 69 5.23E-13 T 28-03-2018 IPR002477 Peptidoglycan binding-like CU254_RS39175 206bbbf2da0e0c594acea6582ccedd60 382 Gene3D G3DSA:1.10.101.10 1 79 1.5E-16 T 28-03-2018 IPR002477 Peptidoglycan binding-like CU254_RS39175 206bbbf2da0e0c594acea6582ccedd60 382 Gene3D G3DSA:3.40.630.40 160 360 1.1E-43 T 28-03-2018 CU254_RS19965 0bf1597cf1b56f2b3ff95f77ac0c6a09 633 SUPERFAMILY SSF49998 204 624 8.11E-160 T 28-03-2018 IPR015798 Copper amine oxidase, C-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 CU254_RS19965 0bf1597cf1b56f2b3ff95f77ac0c6a09 633 Gene3D G3DSA:3.10.450.40 101 187 8.4E-23 T 28-03-2018 CU254_RS19965 0bf1597cf1b56f2b3ff95f77ac0c6a09 633 Gene3D G3DSA:3.10.450.40 1 99 1.0E-19 T 28-03-2018 CU254_RS19965 0bf1597cf1b56f2b3ff95f77ac0c6a09 633 SUPERFAMILY SSF54416 2 93 2.22E-17 T 28-03-2018 IPR016182 Copper amine oxidase, N-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 CU254_RS19965 0bf1597cf1b56f2b3ff95f77ac0c6a09 633 Pfam PF02727 Copper amine oxidase, N2 domain 3 85 2.8E-7 T 28-03-2018 IPR015800 Copper amine oxidase, N2-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 CU254_RS19965 0bf1597cf1b56f2b3ff95f77ac0c6a09 633 ProSitePatterns PS01164 Copper amine oxidase topaquinone signature. 366 379 - T 28-03-2018 IPR000269 Copper amine oxidase GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 CU254_RS19965 0bf1597cf1b56f2b3ff95f77ac0c6a09 633 SUPERFAMILY SSF54416 95 205 1.11E-27 T 28-03-2018 IPR016182 Copper amine oxidase, N-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 CU254_RS19965 0bf1597cf1b56f2b3ff95f77ac0c6a09 633 Gene3D G3DSA:2.70.98.20 188 630 2.2E-182 T 28-03-2018 IPR015798 Copper amine oxidase, C-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 CU254_RS19965 0bf1597cf1b56f2b3ff95f77ac0c6a09 633 Pfam PF02728 Copper amine oxidase, N3 domain 96 192 4.8E-14 T 28-03-2018 IPR015802 Copper amine oxidase, N3-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 CU254_RS19965 0bf1597cf1b56f2b3ff95f77ac0c6a09 633 Pfam PF01179 Copper amine oxidase, enzyme domain 217 622 1.2E-159 T 28-03-2018 IPR015798 Copper amine oxidase, C-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 CU254_RS01320 48eae2c301e6c2d1da70147bd5d18aee 152 Gene3D G3DSA:1.10.10.10 122 146 0.45 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS01320 48eae2c301e6c2d1da70147bd5d18aee 152 SUPERFAMILY SSF46785 10 138 3.33E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS01320 48eae2c301e6c2d1da70147bd5d18aee 152 SMART SM00347 26 126 4.4E-20 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS01320 48eae2c301e6c2d1da70147bd5d18aee 152 Pfam PF12802 MarR family 31 89 3.1E-14 T 28-03-2018 CU254_RS01320 48eae2c301e6c2d1da70147bd5d18aee 152 PRINTS PR00598 Bacterial regulatory protein MarR family signature 86 102 6.7E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS01320 48eae2c301e6c2d1da70147bd5d18aee 152 PRINTS PR00598 Bacterial regulatory protein MarR family signature 67 82 6.7E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS01320 48eae2c301e6c2d1da70147bd5d18aee 152 PRINTS PR00598 Bacterial regulatory protein MarR family signature 116 136 6.7E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS01320 48eae2c301e6c2d1da70147bd5d18aee 152 Gene3D G3DSA:1.10.10.10 8 121 2.7E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS09055 833c4e2a426c846696d5e9464e6d9ce1 234 Gene3D G3DSA:2.40.10.10 31 63 6.6E-10 T 28-03-2018 CU254_RS09055 833c4e2a426c846696d5e9464e6d9ce1 234 Pfam PF00089 Trypsin 31 228 1.7E-25 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CU254_RS09055 833c4e2a426c846696d5e9464e6d9ce1 234 Gene3D G3DSA:2.40.10.10 64 113 5.9E-11 T 28-03-2018 CU254_RS09055 833c4e2a426c846696d5e9464e6d9ce1 234 SMART SM00020 30 228 1.4E-12 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CU254_RS09055 833c4e2a426c846696d5e9464e6d9ce1 234 Gene3D G3DSA:2.40.10.10 114 233 8.2E-19 T 28-03-2018 CU254_RS09055 833c4e2a426c846696d5e9464e6d9ce1 234 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 181 193 5.2E-10 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CU254_RS09055 833c4e2a426c846696d5e9464e6d9ce1 234 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 60 75 5.2E-10 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CU254_RS09055 833c4e2a426c846696d5e9464e6d9ce1 234 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 104 118 5.2E-10 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CU254_RS09055 833c4e2a426c846696d5e9464e6d9ce1 234 SUPERFAMILY SSF50494 24 232 5.62E-36 T 28-03-2018 IPR009003 Peptidase S1, PA clan CU254_RS27135 e362b1f521f0f7dc6df9a719e9ad9555 125 Pfam PF01638 HxlR-like helix-turn-helix 24 111 6.2E-28 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type CU254_RS27135 e362b1f521f0f7dc6df9a719e9ad9555 125 SUPERFAMILY SSF46785 14 117 2.59E-34 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS27135 e362b1f521f0f7dc6df9a719e9ad9555 125 Gene3D G3DSA:1.10.10.10 5 124 4.3E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS24880 632bf7927b18529a89bc73150c882455 749 SMART SM00322 586 651 5.0E-10 T 28-03-2018 IPR004087 K Homology domain GO:0003676 CU254_RS24880 632bf7927b18529a89bc73150c882455 749 Pfam PF01138 3' exoribonuclease family, domain 1 24 155 1.0E-18 T 28-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CU254_RS24880 632bf7927b18529a89bc73150c882455 749 Pfam PF01138 3' exoribonuclease family, domain 1 355 487 2.1E-14 T 28-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CU254_RS24880 632bf7927b18529a89bc73150c882455 749 Gene3D G3DSA:3.30.230.70 343 581 1.7E-51 T 28-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CU254_RS24880 632bf7927b18529a89bc73150c882455 749 SUPERFAMILY SSF50249 654 724 1.29E-14 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CU254_RS24880 632bf7927b18529a89bc73150c882455 749 Pfam PF00575 S1 RNA binding domain 655 724 5.2E-13 T 28-03-2018 IPR003029 S1 domain GO:0003676 CU254_RS24880 632bf7927b18529a89bc73150c882455 749 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 21 726 3.6E-264 T 28-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CU254_RS24880 632bf7927b18529a89bc73150c882455 749 Pfam PF00013 KH domain 590 643 1.3E-9 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CU254_RS24880 632bf7927b18529a89bc73150c882455 749 Pfam PF03725 3' exoribonuclease family, domain 2 490 564 9.9E-7 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CU254_RS24880 632bf7927b18529a89bc73150c882455 749 Gene3D G3DSA:3.30.230.70 21 280 4.6E-45 T 28-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CU254_RS24880 632bf7927b18529a89bc73150c882455 749 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 270 350 3.2E-21 T 28-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CU254_RS24880 632bf7927b18529a89bc73150c882455 749 SUPERFAMILY SSF54211 326 522 1.37E-42 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CU254_RS24880 632bf7927b18529a89bc73150c882455 749 Gene3D G3DSA:1.10.10.400 281 342 2.0E-26 T 28-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CU254_RS24880 632bf7927b18529a89bc73150c882455 749 Gene3D G3DSA:2.40.50.140 658 731 5.0E-17 T 28-03-2018 CU254_RS24880 632bf7927b18529a89bc73150c882455 749 TIGRFAM TIGR02696 pppGpp_PNP: guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase 9 725 0.0 T 28-03-2018 IPR014069 Guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase GO:0004654|GO:0005737|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CU254_RS24880 632bf7927b18529a89bc73150c882455 749 PIRSF PIRSF005499 11 749 3.6E-285 T 28-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CU254_RS24880 632bf7927b18529a89bc73150c882455 749 SUPERFAMILY SSF54211 12 155 2.48E-45 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CU254_RS24880 632bf7927b18529a89bc73150c882455 749 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 13 730 27.034 T 28-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CU254_RS24880 632bf7927b18529a89bc73150c882455 749 SMART SM00316 656 727 4.5E-17 T 28-03-2018 IPR022967 RNA-binding domain, S1 CU254_RS24880 632bf7927b18529a89bc73150c882455 749 SUPERFAMILY SSF46915 267 352 9.94E-18 T 28-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CU254_RS24880 632bf7927b18529a89bc73150c882455 749 SUPERFAMILY SSF54791 589 675 4.99E-17 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CU254_RS24880 632bf7927b18529a89bc73150c882455 749 SUPERFAMILY SSF55666 156 262 9.16E-25 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CU254_RS24880 632bf7927b18529a89bc73150c882455 749 SUPERFAMILY SSF55666 481 580 6.71E-24 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CU254_RS24880 632bf7927b18529a89bc73150c882455 749 Gene3D G3DSA:3.30.1370.10 582 657 1.5E-12 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CU254_RS40560 e4412381ba826dcab9c8227354095b5a 365 Gene3D G3DSA:3.30.300.50 109 179 4.0E-17 T 28-03-2018 IPR035070 Streptogrisin prodomain CU254_RS40560 e4412381ba826dcab9c8227354095b5a 365 PIRSF PIRSF001134 2 365 2.2E-95 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CU254_RS40560 e4412381ba826dcab9c8227354095b5a 365 Gene3D G3DSA:3.30.300.50 31 108 1.1E-23 T 28-03-2018 IPR035070 Streptogrisin prodomain CU254_RS40560 e4412381ba826dcab9c8227354095b5a 365 SUPERFAMILY SSF50494 190 358 1.83E-29 T 28-03-2018 IPR009003 Peptidase S1, PA clan CU254_RS40560 e4412381ba826dcab9c8227354095b5a 365 Pfam PF02983 Alpha-lytic protease prodomain 112 170 1.3E-13 T 28-03-2018 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 CU254_RS40560 e4412381ba826dcab9c8227354095b5a 365 Gene3D G3DSA:2.40.10.10 267 350 2.6E-16 T 28-03-2018 CU254_RS40560 e4412381ba826dcab9c8227354095b5a 365 Pfam PF00089 Trypsin 205 348 8.5E-6 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CU254_RS40560 e4412381ba826dcab9c8227354095b5a 365 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 211 225 5.5E-31 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CU254_RS40560 e4412381ba826dcab9c8227354095b5a 365 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 269 289 5.5E-31 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CU254_RS40560 e4412381ba826dcab9c8227354095b5a 365 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 290 307 5.5E-31 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CU254_RS40560 e4412381ba826dcab9c8227354095b5a 365 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 309 332 5.5E-31 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CU254_RS40560 e4412381ba826dcab9c8227354095b5a 365 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 333 347 5.5E-31 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CU254_RS40560 e4412381ba826dcab9c8227354095b5a 365 Gene3D G3DSA:2.40.10.10 188 266 1.6E-14 T 28-03-2018 CU254_RS20390 e81fb341ca5d59a586ecf52011025f4c 188 SUPERFAMILY SSF48498 107 182 8.26E-5 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS20390 e81fb341ca5d59a586ecf52011025f4c 188 Gene3D G3DSA:1.10.357.10 43 186 1.0E-13 T 28-03-2018 CU254_RS20390 e81fb341ca5d59a586ecf52011025f4c 188 Gene3D G3DSA:1.10.10.60 4 42 2.8E-6 T 28-03-2018 CU254_RS20390 e81fb341ca5d59a586ecf52011025f4c 188 SUPERFAMILY SSF46689 8 78 3.33E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS40555 c73fcd0664d1a12e8d1777ddb5140483 934 SUPERFAMILY SSF52540 7 78 1.87E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS40555 c73fcd0664d1a12e8d1777ddb5140483 934 SUPERFAMILY SSF52540 112 247 1.87E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS40555 c73fcd0664d1a12e8d1777ddb5140483 934 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 874 888 5.6E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS40555 c73fcd0664d1a12e8d1777ddb5140483 934 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 888 904 5.6E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS40555 c73fcd0664d1a12e8d1777ddb5140483 934 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 904 916 5.6E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS40555 c73fcd0664d1a12e8d1777ddb5140483 934 SUPERFAMILY SSF46894 867 927 2.45E-18 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS40555 c73fcd0664d1a12e8d1777ddb5140483 934 Gene3D G3DSA:1.10.10.10 780 927 3.9E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS40555 c73fcd0664d1a12e8d1777ddb5140483 934 SMART SM00421 871 928 4.7E-24 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS40555 c73fcd0664d1a12e8d1777ddb5140483 934 Pfam PF00196 Bacterial regulatory proteins, luxR family 874 926 5.2E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS40555 c73fcd0664d1a12e8d1777ddb5140483 934 Gene3D G3DSA:1.25.40.10 346 686 7.0E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS40555 c73fcd0664d1a12e8d1777ddb5140483 934 SMART SM00382 35 224 3.2E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS40555 c73fcd0664d1a12e8d1777ddb5140483 934 Pfam PF13191 AAA ATPase domain 18 169 9.0E-19 T 28-03-2018 CU254_RS40555 c73fcd0664d1a12e8d1777ddb5140483 934 SUPERFAMILY SSF48452 655 851 7.21E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS40555 c73fcd0664d1a12e8d1777ddb5140483 934 Gene3D G3DSA:3.40.50.300 9 187 1.2E-7 T 28-03-2018 CU254_RS09795 ada1d409d7222d6aabe5c367f0798268 230 Gene3D G3DSA:2.40.10.10 28 230 8.9E-43 T 28-03-2018 CU254_RS09795 ada1d409d7222d6aabe5c367f0798268 230 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 18 33 6.7E-14 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CU254_RS09795 ada1d409d7222d6aabe5c367f0798268 230 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 79 93 6.7E-14 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CU254_RS09795 ada1d409d7222d6aabe5c367f0798268 230 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 166 178 6.7E-14 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CU254_RS09795 ada1d409d7222d6aabe5c367f0798268 230 Gene3D G3DSA:2.40.10.10 1 27 7.8E-10 T 28-03-2018 CU254_RS09795 ada1d409d7222d6aabe5c367f0798268 230 SUPERFAMILY SSF50494 11 225 1.46E-45 T 28-03-2018 IPR009003 Peptidase S1, PA clan CU254_RS09795 ada1d409d7222d6aabe5c367f0798268 230 Pfam PF00089 Trypsin 14 219 1.1E-33 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CU254_RS09795 ada1d409d7222d6aabe5c367f0798268 230 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 28 33 - T 28-03-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 CU254_RS09795 ada1d409d7222d6aabe5c367f0798268 230 SMART SM00020 6 219 5.4E-28 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CU254_RS16300 0cb8c97471adf37bc96ff14d7ebeabe0 844 SUPERFAMILY SSF56112 223 415 2.83E-27 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS16300 0cb8c97471adf37bc96ff14d7ebeabe0 844 Pfam PF00069 Protein kinase domain 235 403 5.0E-13 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CU254_RS16300 0cb8c97471adf37bc96ff14d7ebeabe0 844 Gene3D G3DSA:1.10.510.10 222 451 1.1E-25 T 28-03-2018 CU254_RS16300 0cb8c97471adf37bc96ff14d7ebeabe0 844 Gene3D G3DSA:3.30.2430.10 36 180 1.4E-28 T 28-03-2018 CU254_RS16300 0cb8c97471adf37bc96ff14d7ebeabe0 844 SUPERFAMILY SSF158745 510 828 1.1E-17 T 28-03-2018 CU254_RS16300 0cb8c97471adf37bc96ff14d7ebeabe0 844 Gene3D G3DSA:1.50.10.20 486 730 4.8E-7 T 28-03-2018 CU254_RS16300 0cb8c97471adf37bc96ff14d7ebeabe0 844 SMART SM00220 223 514 1.7E-6 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CU254_RS16300 0cb8c97471adf37bc96ff14d7ebeabe0 844 SMART SM01260 515 829 0.001 T 28-03-2018 IPR007822 Lanthionine synthetase C-like CU254_RS14275 72eebc2086b2a4a73208321cff05cd70 479 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 22 438 4.9E-89 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CU254_RS14275 72eebc2086b2a4a73208321cff05cd70 479 SUPERFAMILY SSF103473 12 201 6.02E-60 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS14275 72eebc2086b2a4a73208321cff05cd70 479 SUPERFAMILY SSF103473 260 471 6.02E-60 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS14275 72eebc2086b2a4a73208321cff05cd70 479 Gene3D G3DSA:1.20.1250.20 258 479 2.4E-23 T 28-03-2018 CU254_RS14275 72eebc2086b2a4a73208321cff05cd70 479 PRINTS PR01036 Tetracycline resistance protein TetB signature 146 170 2.4E-10 T 28-03-2018 CU254_RS14275 72eebc2086b2a4a73208321cff05cd70 479 PRINTS PR01036 Tetracycline resistance protein TetB signature 116 136 2.4E-10 T 28-03-2018 CU254_RS14275 72eebc2086b2a4a73208321cff05cd70 479 PRINTS PR01036 Tetracycline resistance protein TetB signature 25 49 2.4E-10 T 28-03-2018 CU254_RS14275 72eebc2086b2a4a73208321cff05cd70 479 Pfam PF07690 Major Facilitator Superfamily 26 422 1.9E-44 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS14275 72eebc2086b2a4a73208321cff05cd70 479 Gene3D G3DSA:1.20.1250.20 18 205 6.2E-30 T 28-03-2018 CU254_RS06045 8fc996365db735abd3b9e8e04afd3967 439 Gene3D G3DSA:1.10.150.20 174 241 1.8E-18 T 28-03-2018 CU254_RS06045 8fc996365db735abd3b9e8e04afd3967 439 Pfam PF11799 impB/mucB/samB family C-terminal domain 236 345 4.6E-17 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CU254_RS06045 8fc996365db735abd3b9e8e04afd3967 439 Gene3D G3DSA:3.30.1490.100 242 349 8.7E-22 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CU254_RS06045 8fc996365db735abd3b9e8e04afd3967 439 Gene3D G3DSA:3.30.70.270 41 114 2.6E-16 T 28-03-2018 CU254_RS06045 8fc996365db735abd3b9e8e04afd3967 439 Gene3D G3DSA:3.30.70.270 115 173 6.1E-14 T 28-03-2018 CU254_RS06045 8fc996365db735abd3b9e8e04afd3967 439 SUPERFAMILY SSF56672 2 240 7.12E-68 T 28-03-2018 CU254_RS06045 8fc996365db735abd3b9e8e04afd3967 439 SUPERFAMILY SSF100879 242 340 1.0E-20 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CU254_RS06045 8fc996365db735abd3b9e8e04afd3967 439 Pfam PF00817 impB/mucB/samB family 8 155 1.3E-37 T 28-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CU254_RS06045 8fc996365db735abd3b9e8e04afd3967 439 Pfam PF11798 IMS family HHH motif 169 199 3.1E-8 T 28-03-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 CU254_RS06045 8fc996365db735abd3b9e8e04afd3967 439 Hamap MF_01113 DNA polymerase IV [dinB]. 2 355 32.867 T 28-03-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 CU254_RS38720 7231067136cf3a5f603cb68c79614727 201 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS38720 7231067136cf3a5f603cb68c79614727 201 SMART SM00382 26 200 4.8E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS38720 7231067136cf3a5f603cb68c79614727 201 SUPERFAMILY SSF52540 7 200 4.07E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS38720 7231067136cf3a5f603cb68c79614727 201 Pfam PF00005 ABC transporter 17 155 1.1E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS38720 7231067136cf3a5f603cb68c79614727 201 Gene3D G3DSA:3.40.50.300 1 200 4.4E-43 T 28-03-2018 CU254_RS37725 a3adb11acb9375bc4b8db77a132bc21e 228 Gene3D G3DSA:3.20.20.370 16 153 4.1E-10 T 28-03-2018 CU254_RS37725 a3adb11acb9375bc4b8db77a132bc21e 228 Pfam PF10096 Uncharacterized protein conserved in bacteria (DUF2334) 39 139 1.0E-11 T 28-03-2018 IPR018763 Protein of unknown function DUF2334 CU254_RS37725 a3adb11acb9375bc4b8db77a132bc21e 228 SUPERFAMILY SSF88713 23 137 6.39E-9 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CU254_RS02565 23719e4eac88d86fe5c687b343b3fd4a 804 SUPERFAMILY SSF52540 22 696 6.06E-178 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS02565 23719e4eac88d86fe5c687b343b3fd4a 804 TIGRFAM TIGR01073 pcrA: ATP-dependent DNA helicase PcrA 23 794 8.8E-292 T 28-03-2018 IPR005751 ATP-dependent DNA helicase PcrA GO:0004003|GO:0005737|GO:0006268 CU254_RS02565 23719e4eac88d86fe5c687b343b3fd4a 804 Gene3D G3DSA:3.40.50.300 308 411 1.1E-26 T 28-03-2018 CU254_RS02565 23719e4eac88d86fe5c687b343b3fd4a 804 Pfam PF00580 UvrD/REP helicase N-terminal domain 27 297 4.1E-82 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CU254_RS02565 23719e4eac88d86fe5c687b343b3fd4a 804 Pfam PF13361 UvrD-like helicase C-terminal domain 303 669 1.7E-62 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CU254_RS02565 23719e4eac88d86fe5c687b343b3fd4a 804 Gene3D G3DSA:3.40.50.300 441 718 1.1E-51 T 28-03-2018 CU254_RS02565 23719e4eac88d86fe5c687b343b3fd4a 804 Gene3D G3DSA:3.40.50.300 20 154 1.1E-29 T 28-03-2018 CU254_RS02565 23719e4eac88d86fe5c687b343b3fd4a 804 Gene3D G3DSA:3.40.50.300 155 307 1.7E-35 T 28-03-2018 CU254_RS27480 448c6c8d899ab86be1524aecf1a6fba5 269 Gene3D G3DSA:1.10.8.50 117 268 9.3E-48 T 28-03-2018 CU254_RS27480 448c6c8d899ab86be1524aecf1a6fba5 269 ProSitePatterns PS01242 Zinc finger FPG-type signature. 243 267 - T 28-03-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 CU254_RS27480 448c6c8d899ab86be1524aecf1a6fba5 269 SUPERFAMILY SSF57716 221 268 3.92E-13 T 28-03-2018 CU254_RS27480 448c6c8d899ab86be1524aecf1a6fba5 269 Pfam PF06827 Zinc finger found in FPG and IleRS 242 268 2.2E-6 T 28-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 CU254_RS27480 448c6c8d899ab86be1524aecf1a6fba5 269 Gene3D G3DSA:3.20.190.10 1 116 1.5E-19 T 28-03-2018 CU254_RS27480 448c6c8d899ab86be1524aecf1a6fba5 269 SUPERFAMILY SSF46946 121 206 5.0E-24 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CU254_RS27480 448c6c8d899ab86be1524aecf1a6fba5 269 SMART SM00898 2 108 1.4E-15 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CU254_RS27480 448c6c8d899ab86be1524aecf1a6fba5 269 SMART SM01232 122 214 2.4E-33 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CU254_RS27480 448c6c8d899ab86be1524aecf1a6fba5 269 SUPERFAMILY SSF81624 2 123 4.06E-21 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CU254_RS27480 448c6c8d899ab86be1524aecf1a6fba5 269 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 122 207 4.8E-20 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CU254_RS07910 ead746fd72078db11c1ea4deedc9f372 445 Gene3D G3DSA:1.10.3430.10 1 399 5.9E-132 T 28-03-2018 CU254_RS07910 ead746fd72078db11c1ea4deedc9f372 445 TIGRFAM TIGR00836 amt: ammonium transporter 1 418 2.7E-139 T 28-03-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 CU254_RS07910 ead746fd72078db11c1ea4deedc9f372 445 Pfam PF00909 Ammonium Transporter Family 1 418 1.1E-128 T 28-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 CU254_RS07910 ead746fd72078db11c1ea4deedc9f372 445 SUPERFAMILY SSF111352 1 399 1.83E-120 T 28-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 CU254_RS07910 ead746fd72078db11c1ea4deedc9f372 445 ProSitePatterns PS01219 Ammonium transporters signature. 173 198 - T 28-03-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 CU254_RS01200 a790be4cb2d55109892cd0de8fdfbbc7 170 Pfam PF03073 TspO/MBR family 26 164 2.5E-33 T 28-03-2018 IPR004307 TspO/MBR-related protein GO:0016021 CU254_RS01200 a790be4cb2d55109892cd0de8fdfbbc7 170 PIRSF PIRSF005859 14 168 1.5E-36 T 28-03-2018 IPR004307 TspO/MBR-related protein GO:0016021 CU254_RS27895 6141f90502a295bfc97db23bce0d1e5e 253 TIGRFAM TIGR02434 CobF: precorrin-6A synthase (deacetylating) 2 251 4.0E-107 T 28-03-2018 IPR012797 Cobalamin (vitamin B12) biosynthesis CobF, precorrin-6A synthase GO:0009236|GO:0043819 KEGG: 00860+2.1.1.152|MetaCyc: PWY-7376 CU254_RS27895 6141f90502a295bfc97db23bce0d1e5e 253 Gene3D G3DSA:3.30.950.10 155 251 2.8E-43 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CU254_RS27895 6141f90502a295bfc97db23bce0d1e5e 253 SUPERFAMILY SSF53790 1 251 6.67E-37 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CU254_RS27895 6141f90502a295bfc97db23bce0d1e5e 253 PIRSF PIRSF036525 1 253 6.1E-111 T 28-03-2018 IPR012797 Cobalamin (vitamin B12) biosynthesis CobF, precorrin-6A synthase GO:0009236|GO:0043819 KEGG: 00860+2.1.1.152|MetaCyc: PWY-7376 CU254_RS27895 6141f90502a295bfc97db23bce0d1e5e 253 Gene3D G3DSA:3.40.1010.10 1 154 7.4E-33 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CU254_RS27895 6141f90502a295bfc97db23bce0d1e5e 253 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 223 1.6E-29 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CU254_RS19045 d45cc3976270b458f99902fb9de56f8f 288 SUPERFAMILY SSF51679 1 259 2.75E-48 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS19045 d45cc3976270b458f99902fb9de56f8f 288 Pfam PF00296 Luciferase-like monooxygenase 2 234 7.7E-39 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS19045 d45cc3976270b458f99902fb9de56f8f 288 Gene3D G3DSA:3.20.20.30 1 285 5.5E-54 T 28-03-2018 CU254_RS28465 d183ae0a8d494984698a7ce32e76982f 332 Gene3D G3DSA:1.10.1610.10 1 61 6.9E-25 T 28-03-2018 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CU254_RS28465 d183ae0a8d494984698a7ce32e76982f 332 Pfam PF02277 Phosphoribosyltransferase 1 329 1.3E-108 T 28-03-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CU254_RS28465 d183ae0a8d494984698a7ce32e76982f 332 Gene3D G3DSA:3.40.50.10210 62 316 5.2E-82 T 28-03-2018 CU254_RS28465 d183ae0a8d494984698a7ce32e76982f 332 SUPERFAMILY SSF52733 1 330 1.22E-91 T 28-03-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CU254_RS28465 d183ae0a8d494984698a7ce32e76982f 332 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 5 330 6.3E-101 T 28-03-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CU254_RS38320 93fb89836eddbb41e419f9ba388c3e1f 468 Pfam PF00561 alpha/beta hydrolase fold 70 443 5.6E-31 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS38320 93fb89836eddbb41e419f9ba388c3e1f 468 SUPERFAMILY SSF53474 316 440 4.32E-22 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS38320 93fb89836eddbb41e419f9ba388c3e1f 468 SUPERFAMILY SSF53474 171 225 4.32E-22 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS38320 93fb89836eddbb41e419f9ba388c3e1f 468 SUPERFAMILY SSF53474 71 128 4.32E-22 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS38320 93fb89836eddbb41e419f9ba388c3e1f 468 Gene3D G3DSA:3.40.50.1820 8 450 5.9E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS00390 5607560f1839c24fd7341cc2095feef1 258 SUPERFAMILY SSF51197 17 248 1.83E-28 T 28-03-2018 CU254_RS00390 5607560f1839c24fd7341cc2095feef1 258 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 16 244 4.3E-21 T 28-03-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 CU254_RS00390 5607560f1839c24fd7341cc2095feef1 258 Gene3D G3DSA:3.60.130.10 10 252 1.2E-31 T 28-03-2018 CU254_RS35490 ddf38effacfd95ccca36030cd785534a 143 SMART SM00347 25 125 4.2E-16 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS35490 ddf38effacfd95ccca36030cd785534a 143 Pfam PF01047 MarR family 36 89 5.9E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS35490 ddf38effacfd95ccca36030cd785534a 143 ProSitePatterns PS01117 MarR-type HTH domain signature. 64 98 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CU254_RS35490 ddf38effacfd95ccca36030cd785534a 143 Gene3D G3DSA:1.10.287.100 109 140 2.2E-7 T 28-03-2018 CU254_RS35490 ddf38effacfd95ccca36030cd785534a 143 SUPERFAMILY SSF46785 9 139 7.23E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS35490 ddf38effacfd95ccca36030cd785534a 143 Gene3D G3DSA:1.10.10.10 9 108 6.2E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS03485 d0b5d6b1341ee479d05f6e3eb04e4b6a 512 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 110 283 7.6E-33 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CU254_RS03485 d0b5d6b1341ee479d05f6e3eb04e4b6a 512 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 110 283 1.6E-39 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CU254_RS03485 d0b5d6b1341ee479d05f6e3eb04e4b6a 512 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 380 463 1.9E-10 T 28-03-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain CU254_RS18500 b39daac7272237dfffddc53772c82db5 608 ProSitePatterns PS00211 ABC transporters family signature. 476 490 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS18500 b39daac7272237dfffddc53772c82db5 608 Gene3D G3DSA:1.10.3720.10 12 280 4.9E-35 T 28-03-2018 CU254_RS18500 b39daac7272237dfffddc53772c82db5 608 Pfam PF00005 ABC transporter 348 503 1.8E-21 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS18500 b39daac7272237dfffddc53772c82db5 608 SUPERFAMILY SSF161098 83 268 1.15E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS18500 b39daac7272237dfffddc53772c82db5 608 SUPERFAMILY SSF52540 328 574 6.29E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS18500 b39daac7272237dfffddc53772c82db5 608 SMART SM00382 356 561 1.6E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS18500 b39daac7272237dfffddc53772c82db5 608 Gene3D G3DSA:3.40.50.300 324 606 3.1E-62 T 28-03-2018 CU254_RS18500 b39daac7272237dfffddc53772c82db5 608 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 285 4.2E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS18500 b39daac7272237dfffddc53772c82db5 608 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 19 56 9.7E-11 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CU254_RS00820 e978b4ab8fd5cad5de7f8a4f7a932154 227 Pfam PF06197 Protein of unknown function (DUF998) 16 206 1.3E-14 T 28-03-2018 IPR009339 Protein of unknown function DUF998 CU254_RS39910 0045c09cf3ee41134dc3c09cf5534439 286 SUPERFAMILY SSF57716 227 271 1.63E-10 T 28-03-2018 CU254_RS39910 0045c09cf3ee41134dc3c09cf5534439 286 SUPERFAMILY SSF46946 137 218 9.03E-19 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CU254_RS39910 0045c09cf3ee41134dc3c09cf5534439 286 Gene3D G3DSA:1.10.8.50 133 271 6.3E-33 T 28-03-2018 CU254_RS39910 0045c09cf3ee41134dc3c09cf5534439 286 SUPERFAMILY SSF81624 2 143 4.84E-22 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CU254_RS39910 0045c09cf3ee41134dc3c09cf5534439 286 Gene3D G3DSA:3.20.190.10 1 132 6.7E-25 T 28-03-2018 CU254_RS39910 0045c09cf3ee41134dc3c09cf5534439 286 Pfam PF06827 Zinc finger found in FPG and IleRS 243 270 4.5E-7 T 28-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 CU254_RS39910 0045c09cf3ee41134dc3c09cf5534439 286 SMART SM00898 2 124 3.2E-20 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CU254_RS39910 0045c09cf3ee41134dc3c09cf5534439 286 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 86 1.3E-15 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CU254_RS39910 0045c09cf3ee41134dc3c09cf5534439 286 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 138 219 2.1E-13 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CU254_RS39910 0045c09cf3ee41134dc3c09cf5534439 286 SMART SM01232 138 225 2.7E-18 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CU254_RS29300 ba71292e1bb3a70262d8ab2334267c5f 539 Gene3D G3DSA:3.40.50.970 1 186 2.7E-28 T 28-03-2018 CU254_RS29300 ba71292e1bb3a70262d8ab2334267c5f 539 SUPERFAMILY SSF52518 1 175 3.96E-30 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS29300 ba71292e1bb3a70262d8ab2334267c5f 539 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 1 167 1.3E-33 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CU254_RS29300 ba71292e1bb3a70262d8ab2334267c5f 539 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 189 321 1.7E-17 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CU254_RS29300 ba71292e1bb3a70262d8ab2334267c5f 539 Gene3D G3DSA:3.40.50.970 339 536 1.9E-32 T 28-03-2018 CU254_RS29300 ba71292e1bb3a70262d8ab2334267c5f 539 Gene3D G3DSA:3.40.50.1220 187 338 2.9E-27 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CU254_RS29300 ba71292e1bb3a70262d8ab2334267c5f 539 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 386 531 3.7E-23 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CU254_RS29300 ba71292e1bb3a70262d8ab2334267c5f 539 SUPERFAMILY SSF52518 364 534 4.47E-33 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS29300 ba71292e1bb3a70262d8ab2334267c5f 539 SUPERFAMILY SSF52467 155 350 7.71E-27 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CU254_RS09540 f39addf56ac8b33ccb568a259b422623 609 PRINTS PR00301 70kDa heat shock protein signature 309 325 1.6E-6 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CU254_RS09540 f39addf56ac8b33ccb568a259b422623 609 PRINTS PR00301 70kDa heat shock protein signature 177 187 1.6E-6 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CU254_RS09540 f39addf56ac8b33ccb568a259b422623 609 PRINTS PR00301 70kDa heat shock protein signature 2 15 1.6E-6 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CU254_RS09540 f39addf56ac8b33ccb568a259b422623 609 SUPERFAMILY SSF53067 3 155 3.21E-23 T 28-03-2018 CU254_RS09540 f39addf56ac8b33ccb568a259b422623 609 Pfam PF00012 Hsp70 protein 88 351 1.9E-28 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CU254_RS09540 f39addf56ac8b33ccb568a259b422623 609 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 312 326 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CU254_RS09540 f39addf56ac8b33ccb568a259b422623 609 Gene3D G3DSA:3.30.420.40 177 340 2.9E-24 T 28-03-2018 CU254_RS09540 f39addf56ac8b33ccb568a259b422623 609 SUPERFAMILY SSF53067 167 354 6.82E-32 T 28-03-2018 CU254_RS09540 f39addf56ac8b33ccb568a259b422623 609 Gene3D G3DSA:3.30.420.40 1 176 1.2E-29 T 28-03-2018 CU254_RS01185 38d91716fa10b0f9ca26475ace8c943b 232 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS01185 38d91716fa10b0f9ca26475ace8c943b 232 Pfam PF00005 ABC transporter 24 172 6.5E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS01185 38d91716fa10b0f9ca26475ace8c943b 232 Gene3D G3DSA:3.40.50.300 1 231 4.9E-65 T 28-03-2018 CU254_RS01185 38d91716fa10b0f9ca26475ace8c943b 232 SUPERFAMILY SSF52540 4 227 2.1E-73 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS01185 38d91716fa10b0f9ca26475ace8c943b 232 SMART SM00382 33 227 2.0E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS18020 1ce743b6b5ce897014b877619212ea5e 306 Gene3D G3DSA:1.10.10.60 202 244 8.0E-7 T 28-03-2018 CU254_RS18020 1ce743b6b5ce897014b877619212ea5e 306 Gene3D G3DSA:1.10.10.60 247 296 1.6E-9 T 28-03-2018 CU254_RS18020 1ce743b6b5ce897014b877619212ea5e 306 SUPERFAMILY SSF46689 248 292 2.15E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS18020 1ce743b6b5ce897014b877619212ea5e 306 Pfam PF12833 Helix-turn-helix domain 217 292 5.4E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS18020 1ce743b6b5ce897014b877619212ea5e 306 Gene3D G3DSA:2.60.120.10 12 201 2.6E-5 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS18020 1ce743b6b5ce897014b877619212ea5e 306 SMART SM00342 208 291 3.9E-13 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS35510 fba0cc5ba2f1d46751b50825a4401ee0 66 Pfam PF02597 ThiS family 3 66 8.6E-16 T 28-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 CU254_RS35510 fba0cc5ba2f1d46751b50825a4401ee0 66 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 3 66 1.2E-20 T 28-03-2018 IPR010035 ThiS, thiamine-biosynthesis CU254_RS35510 fba0cc5ba2f1d46751b50825a4401ee0 66 Gene3D G3DSA:3.10.20.30 1 66 3.8E-24 T 28-03-2018 IPR012675 Beta-grasp domain CU254_RS35510 fba0cc5ba2f1d46751b50825a4401ee0 66 SUPERFAMILY SSF54285 1 66 6.11E-17 T 28-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp CU254_RS10795 868eac08d7cd761c3a3a49230413ee4d 217 SMART SM00448 3 115 2.7E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS10795 868eac08d7cd761c3a3a49230413ee4d 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 208 1.1E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS10795 868eac08d7cd761c3a3a49230413ee4d 217 Gene3D G3DSA:3.40.50.2300 2 133 1.0E-35 T 28-03-2018 CU254_RS10795 868eac08d7cd761c3a3a49230413ee4d 217 Pfam PF00072 Response regulator receiver domain 5 116 5.5E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS10795 868eac08d7cd761c3a3a49230413ee4d 217 ProSitePatterns PS00622 LuxR-type HTH domain signature. 168 195 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS10795 868eac08d7cd761c3a3a49230413ee4d 217 SUPERFAMILY SSF46894 138 213 7.82E-21 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS10795 868eac08d7cd761c3a3a49230413ee4d 217 SUPERFAMILY SSF52172 2 132 4.55E-31 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS10795 868eac08d7cd761c3a3a49230413ee4d 217 SMART SM00421 151 208 2.4E-26 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS10795 868eac08d7cd761c3a3a49230413ee4d 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 196 7.6E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS10795 868eac08d7cd761c3a3a49230413ee4d 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 184 7.6E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS10795 868eac08d7cd761c3a3a49230413ee4d 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 168 7.6E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS10795 868eac08d7cd761c3a3a49230413ee4d 217 Gene3D G3DSA:1.10.10.10 134 213 1.1E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS26440 cd65f4b36b39ad223148ceb7779713ab 441 SUPERFAMILY SSF56176 334 407 4.09E-14 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CU254_RS26440 cd65f4b36b39ad223148ceb7779713ab 441 Gene3D G3DSA:3.30.465.10 333 418 2.9E-23 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CU254_RS26440 cd65f4b36b39ad223148ceb7779713ab 441 SMART SM01091 339 421 2.1E-18 T 28-03-2018 IPR005170 Transporter-associated domain CU254_RS26440 cd65f4b36b39ad223148ceb7779713ab 441 Gene3D G3DSA:3.10.580.10 183 332 7.3E-33 T 28-03-2018 CU254_RS26440 cd65f4b36b39ad223148ceb7779713ab 441 Pfam PF01595 Domain of unknown function DUF21 10 187 2.1E-34 T 28-03-2018 IPR002550 Domain of unknown function DUF21 CU254_RS26440 cd65f4b36b39ad223148ceb7779713ab 441 Pfam PF00571 CBS domain 271 323 1.7E-5 T 28-03-2018 IPR000644 CBS domain CU254_RS26440 cd65f4b36b39ad223148ceb7779713ab 441 Pfam PF00571 CBS domain 204 256 1.8E-5 T 28-03-2018 IPR000644 CBS domain CU254_RS26440 cd65f4b36b39ad223148ceb7779713ab 441 Pfam PF03471 Transporter associated domain 340 417 3.9E-11 T 28-03-2018 IPR005170 Transporter-associated domain CU254_RS26440 cd65f4b36b39ad223148ceb7779713ab 441 SUPERFAMILY SSF54631 189 326 1.52E-32 T 28-03-2018 CU254_RS40360 28e8545c0e1ac0f89a0ddc1235e4580d 82 SUPERFAMILY SSF47413 11 77 6.97E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS40360 28e8545c0e1ac0f89a0ddc1235e4580d 82 Pfam PF01381 Helix-turn-helix 17 71 1.6E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS40360 28e8545c0e1ac0f89a0ddc1235e4580d 82 Gene3D G3DSA:1.10.260.40 6 76 3.8E-18 T 28-03-2018 CU254_RS40360 28e8545c0e1ac0f89a0ddc1235e4580d 82 SMART SM00530 16 71 1.9E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS35395 3fb65ba21154e5bfb44d973bed2ac521 67 PRINTS PR00050 Cold shock protein signature 4 19 8.4E-18 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CU254_RS35395 3fb65ba21154e5bfb44d973bed2ac521 67 PRINTS PR00050 Cold shock protein signature 24 33 8.4E-18 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CU254_RS35395 3fb65ba21154e5bfb44d973bed2ac521 67 PRINTS PR00050 Cold shock protein signature 39 57 8.4E-18 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CU254_RS35395 3fb65ba21154e5bfb44d973bed2ac521 67 Gene3D G3DSA:2.40.50.140 1 67 5.4E-27 T 28-03-2018 CU254_RS35395 3fb65ba21154e5bfb44d973bed2ac521 67 Pfam PF00313 'Cold-shock' DNA-binding domain 4 66 9.0E-28 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CU254_RS35395 3fb65ba21154e5bfb44d973bed2ac521 67 PIRSF PIRSF002599 1 67 7.8E-22 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 CU254_RS35395 3fb65ba21154e5bfb44d973bed2ac521 67 SMART SM00357 3 67 3.3E-29 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 CU254_RS35395 3fb65ba21154e5bfb44d973bed2ac521 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 28-03-2018 IPR019844 Cold-shock conserved site CU254_RS35395 3fb65ba21154e5bfb44d973bed2ac521 67 SUPERFAMILY SSF50249 2 66 9.72E-23 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CU254_RS13540 3819f703b246eb2c857fddf22aa9c19c 122 Gene3D G3DSA:3.10.180.10 8 122 5.0E-18 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS13540 3819f703b246eb2c857fddf22aa9c19c 122 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 13 116 1.9E-5 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CU254_RS13540 3819f703b246eb2c857fddf22aa9c19c 122 SUPERFAMILY SSF54593 11 118 6.18E-17 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS32310 bdb398f8b2427e9ff98b3a1d5c3dc7f6 160 Gene3D G3DSA:3.40.630.30 1 87 8.2E-22 T 28-03-2018 CU254_RS32310 bdb398f8b2427e9ff98b3a1d5c3dc7f6 160 Pfam PF00583 Acetyltransferase (GNAT) family 39 136 2.5E-15 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS32310 bdb398f8b2427e9ff98b3a1d5c3dc7f6 160 SUPERFAMILY SSF55729 5 158 5.4E-35 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS32310 bdb398f8b2427e9ff98b3a1d5c3dc7f6 160 Gene3D G3DSA:3.40.630.30 88 151 3.0E-11 T 28-03-2018 CU254_RS30685 bd8fa961a30c3f026f68f7fdc2dc17ad 321 Gene3D G3DSA:3.40.50.880 2 233 4.6E-53 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS30685 bd8fa961a30c3f026f68f7fdc2dc17ad 321 SMART SM00342 231 314 1.9E-19 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS30685 bd8fa961a30c3f026f68f7fdc2dc17ad 321 Gene3D G3DSA:1.10.10.60 234 274 1.9E-10 T 28-03-2018 CU254_RS30685 bd8fa961a30c3f026f68f7fdc2dc17ad 321 Gene3D G3DSA:1.10.10.60 275 318 4.0E-8 T 28-03-2018 CU254_RS30685 bd8fa961a30c3f026f68f7fdc2dc17ad 321 SUPERFAMILY SSF52317 7 196 8.57E-42 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS30685 bd8fa961a30c3f026f68f7fdc2dc17ad 321 SUPERFAMILY SSF46689 268 317 5.38E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS30685 bd8fa961a30c3f026f68f7fdc2dc17ad 321 Pfam PF01965 DJ-1/PfpI family 8 175 5.3E-12 T 28-03-2018 IPR002818 DJ-1/PfpI CU254_RS30685 bd8fa961a30c3f026f68f7fdc2dc17ad 321 Pfam PF12833 Helix-turn-helix domain 237 316 1.5E-17 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS30685 bd8fa961a30c3f026f68f7fdc2dc17ad 321 SUPERFAMILY SSF46689 217 265 1.61E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS26570 13f6796f1b43222be5493a383a740aa5 135 SUPERFAMILY SSF54427 4 134 2.56E-37 T 28-03-2018 IPR032710 NTF2-like domain CU254_RS26570 13f6796f1b43222be5493a383a740aa5 135 Pfam PF14534 Domain of unknown function (DUF4440) 8 121 3.1E-12 T 28-03-2018 IPR027843 Domain of unknown function DUF4440 CU254_RS26570 13f6796f1b43222be5493a383a740aa5 135 Gene3D G3DSA:3.10.450.50 1 132 1.2E-26 T 28-03-2018 CU254_RS26570 13f6796f1b43222be5493a383a740aa5 135 TIGRFAM TIGR02246 TIGR02246: conserved hypothetical protein 3 129 4.3E-27 T 28-03-2018 IPR011944 Steroid delta5-4-isomerase KEGG: 00140+5.3.3.1|KEGG: 00984+5.3.3.1|MetaCyc: PWY-2582|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-699|MetaCyc: PWY-7299 CU254_RS38530 722d6b11b2b6d5858960f239c9b24d4f 305 Gene3D G3DSA:3.40.190.10 36 175 3.7E-33 T 28-03-2018 CU254_RS38530 722d6b11b2b6d5858960f239c9b24d4f 305 SMART SM00062 65 291 3.6E-46 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CU254_RS38530 722d6b11b2b6d5858960f239c9b24d4f 305 SMART SM00079 65 291 0.0031 T 28-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 CU254_RS38530 722d6b11b2b6d5858960f239c9b24d4f 305 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 66 288 2.4E-53 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CU254_RS38530 722d6b11b2b6d5858960f239c9b24d4f 305 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 87 100 - T 28-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 CU254_RS38530 722d6b11b2b6d5858960f239c9b24d4f 305 Gene3D G3DSA:3.40.190.10 176 297 2.5E-13 T 28-03-2018 CU254_RS38530 722d6b11b2b6d5858960f239c9b24d4f 305 SUPERFAMILY SSF53850 4 20 1.74E-56 T 28-03-2018 CU254_RS38530 722d6b11b2b6d5858960f239c9b24d4f 305 SUPERFAMILY SSF53850 55 289 1.74E-56 T 28-03-2018 CU254_RS13425 b32f702cf2cb333f839f8f8b3a7be12a 246 SUPERFAMILY SSF52266 31 236 1.68E-21 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CU254_RS13425 b32f702cf2cb333f839f8f8b3a7be12a 246 Gene3D G3DSA:3.40.50.1110 26 236 8.6E-27 T 28-03-2018 CU254_RS13425 b32f702cf2cb333f839f8f8b3a7be12a 246 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 46 228 1.0E-17 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CU254_RS18110 2a09bf649bf80cb7c0b7080237639b4f 541 ProSitePatterns PS00211 ABC transporters family signature. 464 478 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS18110 2a09bf649bf80cb7c0b7080237639b4f 541 SUPERFAMILY SSF52540 371 537 4.17E-31 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS18110 2a09bf649bf80cb7c0b7080237639b4f 541 Gene3D G3DSA:3.40.50.300 1 325 1.6E-53 T 28-03-2018 CU254_RS18110 2a09bf649bf80cb7c0b7080237639b4f 541 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS18110 2a09bf649bf80cb7c0b7080237639b4f 541 Pfam PF00005 ABC transporter 20 188 7.7E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS18110 2a09bf649bf80cb7c0b7080237639b4f 541 Pfam PF00005 ABC transporter 371 492 1.2E-20 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS18110 2a09bf649bf80cb7c0b7080237639b4f 541 SMART SM00382 29 232 8.8E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS18110 2a09bf649bf80cb7c0b7080237639b4f 541 SMART SM00382 375 540 1.0E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS18110 2a09bf649bf80cb7c0b7080237639b4f 541 SUPERFAMILY SSF52540 129 229 7.46E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS18110 2a09bf649bf80cb7c0b7080237639b4f 541 SUPERFAMILY SSF52540 3 81 7.46E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS18110 2a09bf649bf80cb7c0b7080237639b4f 541 Gene3D G3DSA:3.40.50.300 326 539 4.5E-33 T 28-03-2018 CU254_RS03975 ca195a3db1fa634d5c91014a15ae008b 526 SUPERFAMILY SSF52540 46 74 3.97E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS03975 ca195a3db1fa634d5c91014a15ae008b 526 SUPERFAMILY SSF52540 214 391 3.97E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS03975 ca195a3db1fa634d5c91014a15ae008b 526 Gene3D G3DSA:3.40.50.300 9 391 2.8E-7 T 28-03-2018 CU254_RS12305 78c700851767ec144a9d94b8cd4d52ff 394 SUPERFAMILY SSF51556 52 355 1.28E-51 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS12305 78c700851767ec144a9d94b8cd4d52ff 394 Pfam PF01979 Amidohydrolase family 170 391 6.6E-18 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CU254_RS12305 78c700851767ec144a9d94b8cd4d52ff 394 Gene3D G3DSA:2.30.40.10 1 76 2.7E-17 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS12305 78c700851767ec144a9d94b8cd4d52ff 394 SUPERFAMILY SSF51338 4 53 7.95E-15 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS12305 78c700851767ec144a9d94b8cd4d52ff 394 SUPERFAMILY SSF51338 356 378 7.95E-15 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS12305 78c700851767ec144a9d94b8cd4d52ff 394 Gene3D G3DSA:3.20.20.140 77 376 8.9E-38 T 28-03-2018 CU254_RS16520 770c63c9a22d6a2a8054a733bbf24790 430 Gene3D G3DSA:3.50.50.60 272 377 3.6E-5 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS16520 770c63c9a22d6a2a8054a733bbf24790 430 Gene3D G3DSA:3.50.50.60 93 248 1.8E-24 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS16520 770c63c9a22d6a2a8054a733bbf24790 430 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 294 301 1.6E-5 T 28-03-2018 CU254_RS16520 770c63c9a22d6a2a8054a733bbf24790 430 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 159 184 1.6E-5 T 28-03-2018 CU254_RS16520 770c63c9a22d6a2a8054a733bbf24790 430 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 1.6E-5 T 28-03-2018 CU254_RS16520 770c63c9a22d6a2a8054a733bbf24790 430 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 324 1.7E-58 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS16520 770c63c9a22d6a2a8054a733bbf24790 430 SUPERFAMILY SSF51905 152 335 4.7E-21 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS16520 770c63c9a22d6a2a8054a733bbf24790 430 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 159 177 1.1E-12 T 28-03-2018 CU254_RS16520 770c63c9a22d6a2a8054a733bbf24790 430 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 99 117 1.1E-12 T 28-03-2018 CU254_RS16520 770c63c9a22d6a2a8054a733bbf24790 430 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 279 301 1.1E-12 T 28-03-2018 CU254_RS16520 770c63c9a22d6a2a8054a733bbf24790 430 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 1.1E-12 T 28-03-2018 CU254_RS16520 770c63c9a22d6a2a8054a733bbf24790 430 SUPERFAMILY SSF51905 1 178 9.16E-29 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS16520 770c63c9a22d6a2a8054a733bbf24790 430 Gene3D G3DSA:3.50.50.60 1 92 1.4E-11 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS25540 babbeb9bd6417967a347c53851a448a3 283 SUPERFAMILY SSF56529 63 282 1.96E-67 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CU254_RS25540 babbeb9bd6417967a347c53851a448a3 283 Gene3D G3DSA:3.90.850.10 22 283 3.1E-73 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CU254_RS25540 babbeb9bd6417967a347c53851a448a3 283 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 76 280 4.5E-62 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CU254_RS23445 caa2dafd70ab6137c2d59c47a5f7b6cc 128 Gene3D G3DSA:3.10.450.50 1 126 3.1E-24 T 28-03-2018 CU254_RS23445 caa2dafd70ab6137c2d59c47a5f7b6cc 128 Pfam PF12680 SnoaL-like domain 11 110 1.6E-15 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CU254_RS23445 caa2dafd70ab6137c2d59c47a5f7b6cc 128 SUPERFAMILY SSF54427 1 119 1.81E-26 T 28-03-2018 IPR032710 NTF2-like domain CU254_RS20935 e225f543fa22460805c7ff0378a2ec00 437 Pfam PF08031 Berberine and berberine like 396 432 1.7E-7 T 28-03-2018 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 CU254_RS20935 e225f543fa22460805c7ff0378a2ec00 437 SUPERFAMILY SSF56176 3 208 2.66E-54 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CU254_RS20935 e225f543fa22460805c7ff0378a2ec00 437 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 41 74 - T 28-03-2018 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 CU254_RS20935 e225f543fa22460805c7ff0378a2ec00 437 Gene3D G3DSA:3.30.43.10 17 92 1.6E-23 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CU254_RS20935 e225f543fa22460805c7ff0378a2ec00 437 Gene3D G3DSA:3.30.465.10 93 230 3.8E-36 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CU254_RS20935 e225f543fa22460805c7ff0378a2ec00 437 Pfam PF01565 FAD binding domain 41 173 1.1E-30 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CU254_RS09725 fd9b76f07d4569f449100bde73df6201 833 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 18 610 1.5E-85 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CU254_RS09725 fd9b76f07d4569f449100bde73df6201 833 PRINTS PR00986 Valyl-tRNA synthetase signature 38 49 1.1E-14 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CU254_RS09725 fd9b76f07d4569f449100bde73df6201 833 PRINTS PR00986 Valyl-tRNA synthetase signature 373 386 1.1E-14 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CU254_RS09725 fd9b76f07d4569f449100bde73df6201 833 PRINTS PR00986 Valyl-tRNA synthetase signature 493 514 1.1E-14 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CU254_RS09725 fd9b76f07d4569f449100bde73df6201 833 PRINTS PR00986 Valyl-tRNA synthetase signature 248 265 1.1E-14 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CU254_RS09725 fd9b76f07d4569f449100bde73df6201 833 PRINTS PR00986 Valyl-tRNA synthetase signature 524 542 1.1E-14 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CU254_RS09725 fd9b76f07d4569f449100bde73df6201 833 SUPERFAMILY SSF50677 210 359 3.01E-33 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CU254_RS09725 fd9b76f07d4569f449100bde73df6201 833 Hamap MF_02005 Valine--tRNA ligase [valS]. 5 821 27.002 T 28-03-2018 IPR022874 Valine-tRNA ligase, type 2 GO:0004832 KEGG: 00970+6.1.1.9 CU254_RS09725 fd9b76f07d4569f449100bde73df6201 833 SUPERFAMILY SSF52374 368 612 1.54E-100 T 28-03-2018 CU254_RS09725 fd9b76f07d4569f449100bde73df6201 833 SUPERFAMILY SSF52374 8 211 1.54E-100 T 28-03-2018 CU254_RS09725 fd9b76f07d4569f449100bde73df6201 833 Gene3D G3DSA:3.40.50.620 3 609 6.8E-98 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS09725 fd9b76f07d4569f449100bde73df6201 833 SUPERFAMILY SSF47323 624 827 5.23E-37 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CU254_RS09725 fd9b76f07d4569f449100bde73df6201 833 Pfam PF08264 Anticodon-binding domain of tRNA 649 788 1.1E-27 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CU254_RS09725 fd9b76f07d4569f449100bde73df6201 833 Gene3D G3DSA:1.10.730.10 610 782 1.3E-33 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CU254_RS34965 ba449ceddae93f3037c00d23c68b2878 101 Gene3D G3DSA:2.10.150.10 1 101 1.3E-42 T 28-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CU254_RS34965 ba449ceddae93f3037c00d23c68b2878 101 Hamap MF_01954 Urease subunit beta [ureB]. 1 101 28.76 T 28-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CU254_RS34965 ba449ceddae93f3037c00d23c68b2878 101 Pfam PF00699 Urease beta subunit 3 99 2.8E-40 T 28-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CU254_RS34965 ba449ceddae93f3037c00d23c68b2878 101 SUPERFAMILY SSF51278 1 99 8.5E-43 T 28-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CU254_RS34965 ba449ceddae93f3037c00d23c68b2878 101 TIGRFAM TIGR00192 urease_beta: urease, beta subunit 1 96 9.3E-36 T 28-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CU254_RS07945 0a9954ff0ec863da06e5537e445e00e7 512 Gene3D G3DSA:3.40.50.300 92 299 3.7E-44 T 28-03-2018 CU254_RS07945 0a9954ff0ec863da06e5537e445e00e7 512 Gene3D G3DSA:1.20.120.140 1 91 6.6E-29 T 28-03-2018 CU254_RS07945 0a9954ff0ec863da06e5537e445e00e7 512 SMART SM00963 1 86 1.8E-32 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CU254_RS07945 0a9954ff0ec863da06e5537e445e00e7 512 Pfam PF00448 SRP54-type protein, GTPase domain 100 298 5.0E-71 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CU254_RS07945 0a9954ff0ec863da06e5537e445e00e7 512 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 271 284 - T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CU254_RS07945 0a9954ff0ec863da06e5537e445e00e7 512 SUPERFAMILY SSF52540 42 356 5.38E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS07945 0a9954ff0ec863da06e5537e445e00e7 512 Pfam PF02978 Signal peptide binding domain 330 427 3.0E-29 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CU254_RS07945 0a9954ff0ec863da06e5537e445e00e7 512 TIGRFAM TIGR00959 ffh: signal recognition particle protein 2 428 9.8E-179 T 28-03-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 CU254_RS07945 0a9954ff0ec863da06e5537e445e00e7 512 SMART SM00962 100 298 2.6E-107 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CU254_RS07945 0a9954ff0ec863da06e5537e445e00e7 512 Gene3D G3DSA:1.10.260.30 329 432 3.2E-34 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CU254_RS07945 0a9954ff0ec863da06e5537e445e00e7 512 SUPERFAMILY SSF47446 329 430 1.01E-32 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CU254_RS07945 0a9954ff0ec863da06e5537e445e00e7 512 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 470 33.616 T 28-03-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 CU254_RS07945 0a9954ff0ec863da06e5537e445e00e7 512 SMART SM00382 99 303 4.6E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS07945 0a9954ff0ec863da06e5537e445e00e7 512 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 3.8E-20 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CU254_RS17345 2d5323aed0a6f056e13c0d026d2397ce 562 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 81 456 9.0E-23 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CU254_RS17345 2d5323aed0a6f056e13c0d026d2397ce 562 Gene3D G3DSA:3.90.76.10 16 204 6.0E-13 T 28-03-2018 CU254_RS17345 2d5323aed0a6f056e13c0d026d2397ce 562 Gene3D G3DSA:3.40.190.10 209 299 9.2E-7 T 28-03-2018 CU254_RS17345 2d5323aed0a6f056e13c0d026d2397ce 562 Gene3D G3DSA:3.10.105.10 300 529 3.0E-25 T 28-03-2018 CU254_RS17345 2d5323aed0a6f056e13c0d026d2397ce 562 SUPERFAMILY SSF53850 6 538 1.52E-50 T 28-03-2018 CU254_RS14905 6651b7ede81b0c47db5e0e55736b408f 621 Pfam PF01494 FAD binding domain 32 403 6.2E-74 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CU254_RS14905 6651b7ede81b0c47db5e0e55736b408f 621 SUPERFAMILY SSF51905 33 219 1.53E-46 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS14905 6651b7ede81b0c47db5e0e55736b408f 621 SUPERFAMILY SSF51905 324 415 1.53E-46 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS14905 6651b7ede81b0c47db5e0e55736b408f 621 SUPERFAMILY SSF52833 443 618 1.99E-52 T 28-03-2018 IPR012336 Thioredoxin-like fold CU254_RS14905 6651b7ede81b0c47db5e0e55736b408f 621 Gene3D G3DSA:3.50.50.60 9 204 2.1E-9 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS14905 6651b7ede81b0c47db5e0e55736b408f 621 Pfam PF07976 Phenol hydroxylase, C-terminal dimerisation domain 433 586 4.1E-40 T 28-03-2018 IPR012941 Phenol hydroxylase, C-terminal dimerisation domain CU254_RS14905 6651b7ede81b0c47db5e0e55736b408f 621 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 337 352 1.1E-32 T 28-03-2018 CU254_RS14905 6651b7ede81b0c47db5e0e55736b408f 621 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 352 368 1.1E-32 T 28-03-2018 CU254_RS14905 6651b7ede81b0c47db5e0e55736b408f 621 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 34 56 1.1E-32 T 28-03-2018 CU254_RS14905 6651b7ede81b0c47db5e0e55736b408f 621 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 198 213 1.1E-32 T 28-03-2018 CU254_RS14905 6651b7ede81b0c47db5e0e55736b408f 621 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 388 404 1.1E-32 T 28-03-2018 CU254_RS14905 6651b7ede81b0c47db5e0e55736b408f 621 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 370 388 1.1E-32 T 28-03-2018 CU254_RS14905 6651b7ede81b0c47db5e0e55736b408f 621 SUPERFAMILY SSF54373 222 322 3.84E-31 T 28-03-2018 CU254_RS14905 6651b7ede81b0c47db5e0e55736b408f 621 Gene3D G3DSA:3.30.9.10 205 333 1.7E-29 T 28-03-2018 CU254_RS14905 6651b7ede81b0c47db5e0e55736b408f 621 Gene3D G3DSA:3.30.9.10 334 430 1.2E-20 T 28-03-2018 CU254_RS14905 6651b7ede81b0c47db5e0e55736b408f 621 Gene3D G3DSA:3.40.30.20 431 620 1.3E-59 T 28-03-2018 CU254_RS23375 a7f747071472a05cac9f833eb0073411 406 Gene3D G3DSA:1.20.1250.20 202 401 3.6E-11 T 28-03-2018 CU254_RS23375 a7f747071472a05cac9f833eb0073411 406 SUPERFAMILY SSF103473 10 397 2.88E-34 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS23375 a7f747071472a05cac9f833eb0073411 406 Pfam PF07690 Major Facilitator Superfamily 29 350 1.0E-24 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS23375 a7f747071472a05cac9f833eb0073411 406 Gene3D G3DSA:1.20.1250.20 8 199 8.6E-15 T 28-03-2018 CU254_RS13345 ce58d84b377cfe447ea8cfea4df5f76a 124 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 12 114 2.2E-20 T 28-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 CU254_RS13345 ce58d84b377cfe447ea8cfea4df5f76a 124 Gene3D G3DSA:3.30.750.24 8 121 3.1E-15 T 28-03-2018 IPR002645 STAS domain CU254_RS13345 ce58d84b377cfe447ea8cfea4df5f76a 124 Pfam PF01740 STAS domain 22 115 2.5E-10 T 28-03-2018 IPR002645 STAS domain CU254_RS13345 ce58d84b377cfe447ea8cfea4df5f76a 124 SUPERFAMILY SSF52091 12 117 1.94E-19 T 28-03-2018 IPR002645 STAS domain CU254_RS11450 2c17408c1aa7df02fd7a90ce064184d3 187 Pfam PF01132 Elongation factor P (EF-P) OB domain 68 121 3.5E-23 T 28-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 CU254_RS11450 2c17408c1aa7df02fd7a90ce064184d3 187 SMART SM00841 129 184 1.0E-31 T 28-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 CU254_RS11450 2c17408c1aa7df02fd7a90ce064184d3 187 SUPERFAMILY SSF50249 65 127 1.8E-19 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CU254_RS11450 2c17408c1aa7df02fd7a90ce064184d3 187 Gene3D G3DSA:2.30.30.30 2 61 6.6E-25 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 CU254_RS11450 2c17408c1aa7df02fd7a90ce064184d3 187 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 60 1.1E-25 T 28-03-2018 IPR013185 Translation elongation factor, KOW-like CU254_RS11450 2c17408c1aa7df02fd7a90ce064184d3 187 Gene3D G3DSA:2.40.50.140 129 184 3.7E-26 T 28-03-2018 CU254_RS11450 2c17408c1aa7df02fd7a90ce064184d3 187 SMART SM01185 67 121 9.1E-29 T 28-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 CU254_RS11450 2c17408c1aa7df02fd7a90ce064184d3 187 SUPERFAMILY SSF50249 129 185 2.91E-17 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CU254_RS11450 2c17408c1aa7df02fd7a90ce064184d3 187 Gene3D G3DSA:2.40.50.140 65 126 4.5E-24 T 28-03-2018 CU254_RS11450 2c17408c1aa7df02fd7a90ce064184d3 187 Hamap MF_00141 Elongation factor P [efp]. 1 185 49.487 T 28-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 CU254_RS11450 2c17408c1aa7df02fd7a90ce064184d3 187 ProSitePatterns PS01275 Elongation factor P signature. 150 169 - T 28-03-2018 IPR013852 Translation elongation factor P/YeiP, conserved site CU254_RS11450 2c17408c1aa7df02fd7a90ce064184d3 187 Pfam PF09285 Elongation factor P, C-terminal 129 184 3.0E-24 T 28-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 CU254_RS11450 2c17408c1aa7df02fd7a90ce064184d3 187 PIRSF PIRSF005901 1 186 9.0E-69 T 28-03-2018 IPR020599 Translation elongation factor P/YeiP CU254_RS11450 2c17408c1aa7df02fd7a90ce064184d3 187 TIGRFAM TIGR00038 efp: translation elongation factor P 3 185 1.1E-77 T 28-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 CU254_RS11450 2c17408c1aa7df02fd7a90ce064184d3 187 SUPERFAMILY SSF50104 2 63 2.47E-19 T 28-03-2018 IPR008991 Translation protein SH3-like domain CU254_RS00235 9abb9aa4812f5138335cb26a1f32b0eb 535 Pfam PF00501 AMP-binding enzyme 27 430 1.2E-73 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS00235 9abb9aa4812f5138335cb26a1f32b0eb 535 Gene3D G3DSA:3.40.50.980 159 323 8.0E-31 T 28-03-2018 CU254_RS00235 9abb9aa4812f5138335cb26a1f32b0eb 535 SUPERFAMILY SSF56801 11 532 1.57E-96 T 28-03-2018 CU254_RS00235 9abb9aa4812f5138335cb26a1f32b0eb 535 Gene3D G3DSA:3.40.50.980 3 158 3.9E-29 T 28-03-2018 CU254_RS00235 9abb9aa4812f5138335cb26a1f32b0eb 535 Gene3D G3DSA:3.30.300.30 423 530 9.3E-13 T 28-03-2018 CU254_RS00235 9abb9aa4812f5138335cb26a1f32b0eb 535 Gene3D G3DSA:2.30.38.10 332 422 4.3E-19 T 28-03-2018 CU254_RS30950 5c4f3b9a7ab1a21fd4cd70ccfc1e6c57 258 ProSitePatterns PS01277 Ribonuclease PH signature. 117 130 - T 28-03-2018 IPR018336 Ribonuclease PH, conserved site CU254_RS30950 5c4f3b9a7ab1a21fd4cd70ccfc1e6c57 258 SUPERFAMILY SSF54211 3 183 1.37E-41 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CU254_RS30950 5c4f3b9a7ab1a21fd4cd70ccfc1e6c57 258 Pfam PF01138 3' exoribonuclease family, domain 1 11 141 8.9E-21 T 28-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CU254_RS30950 5c4f3b9a7ab1a21fd4cd70ccfc1e6c57 258 Hamap MF_00564 Ribonuclease PH [rph]. 2 239 45.571 T 28-03-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 CU254_RS30950 5c4f3b9a7ab1a21fd4cd70ccfc1e6c57 258 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 3 238 4.0E-109 T 28-03-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 CU254_RS30950 5c4f3b9a7ab1a21fd4cd70ccfc1e6c57 258 SUPERFAMILY SSF55666 156 239 5.5E-22 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CU254_RS30950 5c4f3b9a7ab1a21fd4cd70ccfc1e6c57 258 Pfam PF03725 3' exoribonuclease family, domain 2 161 225 2.6E-9 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CU254_RS30950 5c4f3b9a7ab1a21fd4cd70ccfc1e6c57 258 Gene3D G3DSA:3.30.230.70 2 240 1.5E-55 T 28-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CU254_RS24510 32235ee58dcf638711680e63f75c4fa5 237 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 8 231 1.9E-71 T 28-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase CU254_RS24510 32235ee58dcf638711680e63f75c4fa5 237 Gene3D G3DSA:3.60.140.10 1 237 6.4E-85 T 28-03-2018 CU254_RS24510 32235ee58dcf638711680e63f75c4fa5 237 SUPERFAMILY SSF64438 3 234 8.97E-73 T 28-03-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic CU254_RS24510 32235ee58dcf638711680e63f75c4fa5 237 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 14 232 3.3E-53 T 28-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase CU254_RS17395 0ca3d4399688d1fa5cdffca1265938b6 317 Gene3D G3DSA:1.20.120.450 38 199 4.4E-14 T 28-03-2018 CU254_RS17395 0ca3d4399688d1fa5cdffca1265938b6 317 SUPERFAMILY SSF109854 48 197 2.75E-13 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CU254_RS17395 0ca3d4399688d1fa5cdffca1265938b6 317 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 53 193 3.8E-10 T 28-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CU254_RS11680 56512276ea7da35aeb395fb650c6bd3d 404 Gene3D G3DSA:3.40.50.1260 188 390 1.3E-83 T 28-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CU254_RS11680 56512276ea7da35aeb395fb650c6bd3d 404 PIRSF PIRSF000724 1 404 2.7E-132 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CU254_RS11680 56512276ea7da35aeb395fb650c6bd3d 404 Gene3D G3DSA:3.40.50.1260 3 187 1.2E-57 T 28-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CU254_RS11680 56512276ea7da35aeb395fb650c6bd3d 404 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 5 402 40.716 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CU254_RS11680 56512276ea7da35aeb395fb650c6bd3d 404 PRINTS PR00477 Phosphoglycerate kinase family signature 199 218 4.7E-77 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CU254_RS11680 56512276ea7da35aeb395fb650c6bd3d 404 PRINTS PR00477 Phosphoglycerate kinase family signature 321 346 4.7E-77 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CU254_RS11680 56512276ea7da35aeb395fb650c6bd3d 404 PRINTS PR00477 Phosphoglycerate kinase family signature 13 29 4.7E-77 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CU254_RS11680 56512276ea7da35aeb395fb650c6bd3d 404 PRINTS PR00477 Phosphoglycerate kinase family signature 112 127 4.7E-77 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CU254_RS11680 56512276ea7da35aeb395fb650c6bd3d 404 PRINTS PR00477 Phosphoglycerate kinase family signature 176 198 4.7E-77 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CU254_RS11680 56512276ea7da35aeb395fb650c6bd3d 404 PRINTS PR00477 Phosphoglycerate kinase family signature 354 365 4.7E-77 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CU254_RS11680 56512276ea7da35aeb395fb650c6bd3d 404 PRINTS PR00477 Phosphoglycerate kinase family signature 378 395 4.7E-77 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CU254_RS11680 56512276ea7da35aeb395fb650c6bd3d 404 PRINTS PR00477 Phosphoglycerate kinase family signature 34 56 4.7E-77 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CU254_RS11680 56512276ea7da35aeb395fb650c6bd3d 404 PRINTS PR00477 Phosphoglycerate kinase family signature 146 168 4.7E-77 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CU254_RS11680 56512276ea7da35aeb395fb650c6bd3d 404 Pfam PF00162 Phosphoglycerate kinase 14 392 1.7E-143 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CU254_RS11680 56512276ea7da35aeb395fb650c6bd3d 404 SUPERFAMILY SSF53748 5 402 2.59E-141 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CU254_RS12425 6f5484fa57dd03b6eac35096faa3aac1 61 SUPERFAMILY SSF55331 1 60 4.97E-17 T 28-03-2018 IPR014347 Tautomerase/MIF superfamily CU254_RS12425 6f5484fa57dd03b6eac35096faa3aac1 61 Gene3D G3DSA:3.30.429.10 1 57 4.9E-16 T 28-03-2018 CU254_RS12425 6f5484fa57dd03b6eac35096faa3aac1 61 Pfam PF01361 Tautomerase enzyme 2 60 4.3E-12 T 28-03-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 CU254_RS08940 c9b05049ce6f08616cccb778657cea4d 353 Pfam PF00877 NlpC/P60 family 254 350 2.0E-29 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CU254_RS08940 c9b05049ce6f08616cccb778657cea4d 353 SUPERFAMILY SSF54001 236 352 4.9E-44 T 28-03-2018 CU254_RS08940 c9b05049ce6f08616cccb778657cea4d 353 Gene3D G3DSA:3.90.1720.10 97 286 8.2E-20 T 28-03-2018 CU254_RS08940 c9b05049ce6f08616cccb778657cea4d 353 Gene3D G3DSA:2.30.260.10 287 352 1.4E-22 T 28-03-2018 CU254_RS10225 fc691a97dedf7ac65643782a93d86b53 116 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 23 105 5.5E-29 T 28-03-2018 IPR023845 Domain of unknown function DUF3817, transmembrane CU254_RS10225 fc691a97dedf7ac65643782a93d86b53 116 Pfam PF12823 Domain of unknown function (DUF3817) 20 106 8.3E-27 T 28-03-2018 IPR023845 Domain of unknown function DUF3817, transmembrane CU254_RS24630 5db9a7a867ec8f305915cccf5353a9a4 318 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 3 313 8.2E-90 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CU254_RS24630 5db9a7a867ec8f305915cccf5353a9a4 318 PIRSF PIRSF004486 1 315 5.8E-93 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CU254_RS24630 5db9a7a867ec8f305915cccf5353a9a4 318 SUPERFAMILY SSF53335 219 314 2.05E-38 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS24630 5db9a7a867ec8f305915cccf5353a9a4 318 SUPERFAMILY SSF53335 7 117 2.05E-38 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS24630 5db9a7a867ec8f305915cccf5353a9a4 318 Gene3D G3DSA:1.10.150.170 116 221 9.7E-36 T 28-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CU254_RS24630 5db9a7a867ec8f305915cccf5353a9a4 318 SUPERFAMILY SSF81799 118 219 9.02E-33 T 28-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CU254_RS24630 5db9a7a867ec8f305915cccf5353a9a4 318 Gene3D G3DSA:3.40.50.150 4 90 7.4E-8 T 28-03-2018 CU254_RS24630 5db9a7a867ec8f305915cccf5353a9a4 318 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 7 314 35.84 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CU254_RS24630 5db9a7a867ec8f305915cccf5353a9a4 318 Pfam PF01795 MraW methylase family 5 313 2.6E-108 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CU254_RS07560 978b59f3151dde78a6446ceb724988ec 183 Gene3D G3DSA:2.60.130.10 1 183 2.8E-52 T 28-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 CU254_RS07560 978b59f3151dde78a6446ceb724988ec 183 Pfam PF00775 Dioxygenase 36 173 3.3E-18 T 28-03-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 CU254_RS07560 978b59f3151dde78a6446ceb724988ec 183 TIGRFAM TIGR02423 protocat_alph: protocatechuate 3,4-dioxygenase, alpha subunit 6 183 2.4E-63 T 28-03-2018 IPR012786 Protocatechuate 3,4-dioxygenase, alpha subunit GO:0005506|GO:0018578|GO:0019439|GO:0055114 KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3 CU254_RS07560 978b59f3151dde78a6446ceb724988ec 183 SUPERFAMILY SSF49482 3 182 2.75E-50 T 28-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 CU254_RS36175 12e26a8ef910b14a75c79516f3963351 325 Pfam PF00005 ABC transporter 20 163 2.7E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS36175 12e26a8ef910b14a75c79516f3963351 325 Pfam PF13732 Domain of unknown function (DUF4162) 217 306 7.1E-7 T 28-03-2018 IPR025302 Domain of unknown function DUF4162 CU254_RS36175 12e26a8ef910b14a75c79516f3963351 325 SUPERFAMILY SSF52540 4 226 6.86E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS36175 12e26a8ef910b14a75c79516f3963351 325 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 12 308 1.5E-107 T 28-03-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 CU254_RS36175 12e26a8ef910b14a75c79516f3963351 325 Gene3D G3DSA:3.40.50.300 1 262 8.4E-64 T 28-03-2018 CU254_RS36175 12e26a8ef910b14a75c79516f3963351 325 SMART SM00382 29 212 8.6E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS36175 12e26a8ef910b14a75c79516f3963351 325 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS13470 b4f21d6bff7eaadb042a482e00df081c 535 Gene3D G3DSA:3.90.76.10 68 170 1.2E-25 T 28-03-2018 CU254_RS13470 b4f21d6bff7eaadb042a482e00df081c 535 Gene3D G3DSA:3.40.190.10 171 305 3.3E-29 T 28-03-2018 CU254_RS13470 b4f21d6bff7eaadb042a482e00df081c 535 Gene3D G3DSA:3.10.105.10 306 506 1.8E-43 T 28-03-2018 CU254_RS13470 b4f21d6bff7eaadb042a482e00df081c 535 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 96 445 1.9E-72 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CU254_RS13470 b4f21d6bff7eaadb042a482e00df081c 535 PIRSF PIRSF002741 11 528 2.2E-76 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CU254_RS13470 b4f21d6bff7eaadb042a482e00df081c 535 SUPERFAMILY SSF53850 54 530 3.26E-99 T 28-03-2018 CU254_RS05330 1783901392996c497490641078263d9f 1020 Gene3D G3DSA:3.40.50.300 242 392 9.3E-13 T 28-03-2018 CU254_RS05330 1783901392996c497490641078263d9f 1020 SMART SM01043 90 231 4.1E-46 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CU254_RS05330 1783901392996c497490641078263d9f 1020 SUPERFAMILY SSF48452 86 237 1.67E-29 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS05330 1783901392996c497490641078263d9f 1020 Pfam PF00486 Transcriptional regulatory protein, C terminal 26 71 5.2E-8 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS05330 1783901392996c497490641078263d9f 1020 Gene3D G3DSA:1.25.40.10 574 876 1.6E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS05330 1783901392996c497490641078263d9f 1020 SUPERFAMILY SSF52540 242 519 8.63E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS05330 1783901392996c497490641078263d9f 1020 Pfam PF03704 Bacterial transcriptional activator domain 90 231 1.9E-37 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CU254_RS05330 1783901392996c497490641078263d9f 1020 Gene3D G3DSA:1.25.40.10 88 241 4.3E-20 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS05330 1783901392996c497490641078263d9f 1020 Gene3D G3DSA:1.25.40.10 880 1003 0.03 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS05330 1783901392996c497490641078263d9f 1020 SUPERFAMILY SSF46894 3 76 9.64E-10 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS05330 1783901392996c497490641078263d9f 1020 Gene3D G3DSA:1.10.10.10 1 87 7.6E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS05330 1783901392996c497490641078263d9f 1020 SMART SM00862 16 85 8.3E-6 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS05330 1783901392996c497490641078263d9f 1020 SUPERFAMILY SSF48452 774 954 5.04E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS14595 affbda5a8aee2c3bd367bfd2a5c4833f 291 SUPERFAMILY SSF54637 178 269 8.2E-12 T 28-03-2018 IPR029069 HotDog domain CU254_RS14595 affbda5a8aee2c3bd367bfd2a5c4833f 291 Gene3D G3DSA:3.10.129.10 11 160 1.8E-17 T 28-03-2018 CU254_RS14595 affbda5a8aee2c3bd367bfd2a5c4833f 291 Gene3D G3DSA:3.10.129.10 167 275 4.1E-16 T 28-03-2018 CU254_RS14595 affbda5a8aee2c3bd367bfd2a5c4833f 291 Pfam PF13452 N-terminal half of MaoC dehydratase 17 135 9.5E-9 T 28-03-2018 CU254_RS07635 20a9a7902c8a8d6f9a8c6597e15b374c 410 Gene3D G3DSA:1.20.1250.20 217 410 3.2E-19 T 28-03-2018 CU254_RS07635 20a9a7902c8a8d6f9a8c6597e15b374c 410 SUPERFAMILY SSF103473 27 409 2.62E-41 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS07635 20a9a7902c8a8d6f9a8c6597e15b374c 410 Pfam PF07690 Major Facilitator Superfamily 35 261 9.7E-17 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS07635 20a9a7902c8a8d6f9a8c6597e15b374c 410 Gene3D G3DSA:1.20.1250.20 20 216 7.4E-20 T 28-03-2018 CU254_RS34230 3bb1f34f3a962a9b0aa6e0381239507f 356 PIRSF PIRSF000808 33 356 1.0E-104 T 28-03-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 CU254_RS34230 3bb1f34f3a962a9b0aa6e0381239507f 356 SUPERFAMILY SSF54197 38 198 2.38E-52 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CU254_RS34230 3bb1f34f3a962a9b0aa6e0381239507f 356 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 38 197 9.7E-40 T 28-03-2018 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 CU254_RS34230 3bb1f34f3a962a9b0aa6e0381239507f 356 SUPERFAMILY SSF54197 200 355 1.65E-33 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CU254_RS34230 3bb1f34f3a962a9b0aa6e0381239507f 356 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 210 353 3.3E-17 T 28-03-2018 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 CU254_RS34230 3bb1f34f3a962a9b0aa6e0381239507f 356 TIGRFAM TIGR00209 galT_1: galactose-1-phosphate uridylyltransferase 41 354 6.4E-40 T 28-03-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 CU254_RS34230 3bb1f34f3a962a9b0aa6e0381239507f 356 ProSitePatterns PS00117 Galactose-1-phosphate uridyl transferase family 1 active site signature. 173 190 - T 28-03-2018 IPR019779 Galactose-1-phosphate uridyl transferase, class I His-active site KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 CU254_RS34230 3bb1f34f3a962a9b0aa6e0381239507f 356 Gene3D G3DSA:3.30.428.10 198 356 6.9E-28 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CU254_RS34230 3bb1f34f3a962a9b0aa6e0381239507f 356 Gene3D G3DSA:3.30.428.10 64 197 3.7E-43 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CU254_RS22825 c93f4a07c863e4f2c40335ced6d15a5d 394 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 4 178 4.6E-46 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 CU254_RS22825 c93f4a07c863e4f2c40335ced6d15a5d 394 SUPERFAMILY SSF81301 214 387 7.85E-44 T 28-03-2018 CU254_RS22825 c93f4a07c863e4f2c40335ced6d15a5d 394 Gene3D G3DSA:3.30.460.10 209 389 9.3E-56 T 28-03-2018 CU254_RS22825 c93f4a07c863e4f2c40335ced6d15a5d 394 Pfam PF04229 GrpB protein 213 379 3.4E-45 T 28-03-2018 IPR007344 GrpB/Dephospho-CoA kinase CU254_RS22825 c93f4a07c863e4f2c40335ced6d15a5d 394 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 1 196 25.686 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 CU254_RS22825 c93f4a07c863e4f2c40335ced6d15a5d 394 Pfam PF01121 Dephospho-CoA kinase 4 177 1.3E-59 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 CU254_RS22825 c93f4a07c863e4f2c40335ced6d15a5d 394 SUPERFAMILY SSF52540 1 194 2.52E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS22825 c93f4a07c863e4f2c40335ced6d15a5d 394 Gene3D G3DSA:3.40.50.300 1 194 1.1E-45 T 28-03-2018 CU254_RS10265 d0c7516acee1cfc45d42ecd98804dc56 216 Gene3D G3DSA:3.40.30.10 16 185 2.5E-12 T 28-03-2018 CU254_RS10265 d0c7516acee1cfc45d42ecd98804dc56 216 Pfam PF05988 Bacterial protein of unknown function (DUF899) 5 216 2.8E-77 T 28-03-2018 IPR010296 Protein of unknown function DUF899, thioredoxin-like CU254_RS16945 2ce98affd547af0f81760c94c048775e 215 Pfam PF12697 Alpha/beta hydrolase family 5 207 3.1E-12 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS16945 2ce98affd547af0f81760c94c048775e 215 SUPERFAMILY SSF53474 5 208 3.19E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS16945 2ce98affd547af0f81760c94c048775e 215 Gene3D G3DSA:3.40.50.1820 4 195 1.1E-16 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS05845 0ca36e42ee15ae2310cbf48ea0b0ebdb 467 SUPERFAMILY SSF103473 13 198 4.97E-42 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS05845 0ca36e42ee15ae2310cbf48ea0b0ebdb 467 SUPERFAMILY SSF103473 250 464 4.97E-42 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS05845 0ca36e42ee15ae2310cbf48ea0b0ebdb 467 Gene3D G3DSA:1.20.1250.20 254 466 8.7E-19 T 28-03-2018 CU254_RS05845 0ca36e42ee15ae2310cbf48ea0b0ebdb 467 Pfam PF07690 Major Facilitator Superfamily 24 413 8.9E-35 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS05845 0ca36e42ee15ae2310cbf48ea0b0ebdb 467 Gene3D G3DSA:1.20.1250.20 10 194 3.7E-20 T 28-03-2018 CU254_RS30460 0158114ed29f7592d0863aba1be04d67 494 Gene3D G3DSA:3.40.50.1820 26 462 1.5E-43 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS30460 0158114ed29f7592d0863aba1be04d67 494 SUPERFAMILY SSF53474 80 130 1.28E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS30460 0158114ed29f7592d0863aba1be04d67 494 SUPERFAMILY SSF53474 172 226 1.28E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS30460 0158114ed29f7592d0863aba1be04d67 494 SUPERFAMILY SSF53474 340 460 1.28E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS30460 0158114ed29f7592d0863aba1be04d67 494 Pfam PF00561 alpha/beta hydrolase fold 82 448 3.8E-28 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS18405 084868d528140ee6aa037b3fa971ab04 280 SUPERFAMILY SSF51735 4 241 1.09E-63 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS18405 084868d528140ee6aa037b3fa971ab04 280 Pfam PF00106 short chain dehydrogenase 9 190 2.4E-50 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18405 084868d528140ee6aa037b3fa971ab04 280 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS18405 084868d528140ee6aa037b3fa971ab04 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 2.4E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18405 084868d528140ee6aa037b3fa971ab04 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 2.4E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18405 084868d528140ee6aa037b3fa971ab04 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 2.4E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18405 084868d528140ee6aa037b3fa971ab04 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.4E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18405 084868d528140ee6aa037b3fa971ab04 280 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 2.4E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18405 084868d528140ee6aa037b3fa971ab04 280 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 1.6E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18405 084868d528140ee6aa037b3fa971ab04 280 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 1.6E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18405 084868d528140ee6aa037b3fa971ab04 280 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 1.6E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18405 084868d528140ee6aa037b3fa971ab04 280 Gene3D G3DSA:3.40.50.720 4 280 6.1E-67 T 28-03-2018 CU254_RS18405 084868d528140ee6aa037b3fa971ab04 280 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 189 7.9E-4 T 28-03-2018 CU254_RS21125 13034e277cdc6f5f02c8f50d7dd56319 252 Pfam PF01909 Nucleotidyltransferase domain 22 54 6.2E-7 T 28-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 CU254_RS21125 13034e277cdc6f5f02c8f50d7dd56319 252 SUPERFAMILY SSF81301 11 61 1.47E-9 T 28-03-2018 CU254_RS21125 13034e277cdc6f5f02c8f50d7dd56319 252 Gene3D G3DSA:3.30.460.10 1 143 1.2E-17 T 28-03-2018 CU254_RS12785 f55e85691b02c5551f7b4e6aeced307b 263 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 4 222 1.0E-34 T 28-03-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 CU254_RS12785 f55e85691b02c5551f7b4e6aeced307b 263 SUPERFAMILY SSF51621 3 223 1.05E-57 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CU254_RS12785 f55e85691b02c5551f7b4e6aeced307b 263 Gene3D G3DSA:3.20.20.60 1 237 4.4E-30 T 28-03-2018 CU254_RS07070 98c23d0f314b061de8ececc9b025c7d9 273 Pfam PF13649 Methyltransferase domain 60 151 8.3E-12 T 28-03-2018 CU254_RS07070 98c23d0f314b061de8ececc9b025c7d9 273 Gene3D G3DSA:3.40.50.150 3 211 5.3E-26 T 28-03-2018 CU254_RS07070 98c23d0f314b061de8ececc9b025c7d9 273 SUPERFAMILY SSF53335 36 238 1.13E-27 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS27965 6f0613a9da2c9537f509b40a8f44666d 353 Gene3D G3DSA:3.50.50.60 3 353 4.1E-37 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS27965 6f0613a9da2c9537f509b40a8f44666d 353 SUPERFAMILY SSF51905 263 333 3.45E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS27965 6f0613a9da2c9537f509b40a8f44666d 353 SUPERFAMILY SSF51905 3 165 3.45E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS27965 6f0613a9da2c9537f509b40a8f44666d 353 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 276 291 1.3E-12 T 28-03-2018 CU254_RS27965 6f0613a9da2c9537f509b40a8f44666d 353 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 291 307 1.3E-12 T 28-03-2018 CU254_RS27965 6f0613a9da2c9537f509b40a8f44666d 353 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 1.3E-12 T 28-03-2018 CU254_RS27965 6f0613a9da2c9537f509b40a8f44666d 353 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 144 159 1.3E-12 T 28-03-2018 CU254_RS27965 6f0613a9da2c9537f509b40a8f44666d 353 Pfam PF01494 FAD binding domain 4 312 2.2E-18 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CU254_RS29395 0a44c0b5fd28ab416c344b743359b394 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 9.3E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS29395 0a44c0b5fd28ab416c344b743359b394 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 9.3E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS29395 0a44c0b5fd28ab416c344b743359b394 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 61 3.7E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS29395 0a44c0b5fd28ab416c344b743359b394 208 SUPERFAMILY SSF46689 5 76 7.18E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS29395 0a44c0b5fd28ab416c344b743359b394 208 Gene3D G3DSA:1.10.357.10 59 203 1.0E-25 T 28-03-2018 CU254_RS29395 0a44c0b5fd28ab416c344b743359b394 208 Gene3D G3DSA:1.10.10.60 2 58 9.3E-16 T 28-03-2018 CU254_RS41090 bf6494eade48d49baf5bf7ccf3651bee 935 Pfam PF13424 Tetratricopeptide repeat 803 875 1.0E-12 T 28-03-2018 CU254_RS41090 bf6494eade48d49baf5bf7ccf3651bee 935 Gene3D G3DSA:1.25.40.10 100 268 1.8E-18 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS41090 bf6494eade48d49baf5bf7ccf3651bee 935 SUPERFAMILY SSF46894 8 82 1.36E-10 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS41090 bf6494eade48d49baf5bf7ccf3651bee 935 Gene3D G3DSA:1.25.40.10 880 934 2.9E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS41090 bf6494eade48d49baf5bf7ccf3651bee 935 SMART SM00028 883 916 29.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS41090 bf6494eade48d49baf5bf7ccf3651bee 935 SMART SM00028 723 756 0.4 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS41090 bf6494eade48d49baf5bf7ccf3651bee 935 SMART SM00028 843 876 0.022 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS41090 bf6494eade48d49baf5bf7ccf3651bee 935 SMART SM00028 763 796 140.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS41090 bf6494eade48d49baf5bf7ccf3651bee 935 SMART SM00028 803 836 2.9E-4 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS41090 bf6494eade48d49baf5bf7ccf3651bee 935 SUPERFAMILY SSF48452 94 263 1.76E-29 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS41090 bf6494eade48d49baf5bf7ccf3651bee 935 Gene3D G3DSA:3.40.50.300 269 431 2.5E-14 T 28-03-2018 CU254_RS41090 bf6494eade48d49baf5bf7ccf3651bee 935 SUPERFAMILY SSF48452 723 912 3.54E-19 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS41090 bf6494eade48d49baf5bf7ccf3651bee 935 SMART SM01043 99 241 8.6E-48 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CU254_RS41090 bf6494eade48d49baf5bf7ccf3651bee 935 Pfam PF00486 Transcriptional regulatory protein, C terminal 28 82 7.0E-6 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS41090 bf6494eade48d49baf5bf7ccf3651bee 935 Pfam PF03704 Bacterial transcriptional activator domain 99 241 3.8E-40 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CU254_RS41090 bf6494eade48d49baf5bf7ccf3651bee 935 SUPERFAMILY SSF52540 275 536 8.87E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS41090 bf6494eade48d49baf5bf7ccf3651bee 935 Gene3D G3DSA:1.10.10.10 3 99 4.3E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS41090 bf6494eade48d49baf5bf7ccf3651bee 935 PRINTS PR00364 Disease resistance protein signature 380 394 2.7E-6 T 28-03-2018 CU254_RS41090 bf6494eade48d49baf5bf7ccf3651bee 935 PRINTS PR00364 Disease resistance protein signature 301 316 2.7E-6 T 28-03-2018 CU254_RS41090 bf6494eade48d49baf5bf7ccf3651bee 935 PRINTS PR00364 Disease resistance protein signature 468 482 2.7E-6 T 28-03-2018 CU254_RS41090 bf6494eade48d49baf5bf7ccf3651bee 935 Gene3D G3DSA:3.30.70.100 845 879 6.1E-10 T 28-03-2018 CU254_RS41090 bf6494eade48d49baf5bf7ccf3651bee 935 Gene3D G3DSA:3.30.70.100 773 798 1.2E-6 T 28-03-2018 CU254_RS41090 bf6494eade48d49baf5bf7ccf3651bee 935 Gene3D G3DSA:3.30.70.100 799 844 3.4E-10 T 28-03-2018 CU254_RS41090 bf6494eade48d49baf5bf7ccf3651bee 935 SMART SM00862 23 92 1.1E-4 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS41090 bf6494eade48d49baf5bf7ccf3651bee 935 Pfam PF00931 NB-ARC domain 285 542 3.7E-6 T 28-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 CU254_RS41090 bf6494eade48d49baf5bf7ccf3651bee 935 Gene3D G3DSA:1.10.150.200 704 772 9.8E-13 T 28-03-2018 CU254_RS20925 be9e7a39ed7d2003c864766715569dde 135 SUPERFAMILY SSF55298 2 134 5.5E-30 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CU254_RS20925 be9e7a39ed7d2003c864766715569dde 135 Gene3D G3DSA:3.30.1330.40 2 133 1.5E-28 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CU254_RS20925 be9e7a39ed7d2003c864766715569dde 135 Pfam PF01042 Endoribonuclease L-PSP 12 132 9.7E-21 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family CU254_RS10840 e3ea81f0ac7c6a90be798443fdf28428 335 Gene3D G3DSA:1.10.3720.10 27 297 7.7E-36 T 28-03-2018 CU254_RS10840 e3ea81f0ac7c6a90be798443fdf28428 335 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 126 306 2.1E-26 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS10840 e3ea81f0ac7c6a90be798443fdf28428 335 SUPERFAMILY SSF161098 103 289 3.92E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS10840 e3ea81f0ac7c6a90be798443fdf28428 335 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 31 83 2.3E-10 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CU254_RS28345 384c9a1d6dc0a37ae200e7049878107f 250 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 20 224 1.2E-35 T 28-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CU254_RS28345 384c9a1d6dc0a37ae200e7049878107f 250 Pfam PF08608 Wyosine base formation 183 225 3.9E-5 T 28-03-2018 IPR013917 tRNA wybutosine-synthesis MetaCyc: PWY-7285|MetaCyc: PWY-7286 CU254_RS28345 384c9a1d6dc0a37ae200e7049878107f 250 Gene3D G3DSA:1.20.120.450 7 153 2.3E-18 T 28-03-2018 CU254_RS28345 384c9a1d6dc0a37ae200e7049878107f 250 SUPERFAMILY SSF109854 12 153 5.72E-28 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CU254_RS28345 384c9a1d6dc0a37ae200e7049878107f 250 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 22 146 5.2E-22 T 28-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CU254_RS40090 a243119d304c748d66c2edbd5687032e 470 Gene3D G3DSA:3.30.420.10 11 182 5.6E-12 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS40090 a243119d304c748d66c2edbd5687032e 470 SUPERFAMILY SSF53098 18 177 2.15E-14 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS40090 a243119d304c748d66c2edbd5687032e 470 SUPERFAMILY SSF158682 240 310 5.89E-5 T 28-03-2018 CU254_RS40090 a243119d304c748d66c2edbd5687032e 470 SMART SM00479 22 181 3.9E-4 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CU254_RS40090 a243119d304c748d66c2edbd5687032e 470 Gene3D G3DSA:1.10.3680.10 274 313 3.0E-4 T 28-03-2018 IPR029024 TerB-like CU254_RS11190 02652441ee1ac9f3d17b92526ffa6096 522 SUPERFAMILY SSF53474 366 493 4.66E-17 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS11190 02652441ee1ac9f3d17b92526ffa6096 522 SUPERFAMILY SSF53474 119 176 4.66E-17 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS11190 02652441ee1ac9f3d17b92526ffa6096 522 SUPERFAMILY SSF53474 218 272 4.66E-17 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS11190 02652441ee1ac9f3d17b92526ffa6096 522 Gene3D G3DSA:3.40.50.1820 106 510 2.6E-24 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS11190 02652441ee1ac9f3d17b92526ffa6096 522 Pfam PF08386 TAP-like protein 421 520 3.3E-21 T 28-03-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal CU254_RS34130 d8b3939583279b369a0b2dcec7b301e3 219 Gene3D G3DSA:3.40.630.30 20 205 6.5E-25 T 28-03-2018 CU254_RS34130 d8b3939583279b369a0b2dcec7b301e3 219 Pfam PF13302 Acetyltransferase (GNAT) domain 30 173 2.1E-16 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS34130 d8b3939583279b369a0b2dcec7b301e3 219 SUPERFAMILY SSF55729 29 198 3.01E-36 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS31400 a6bafa4959c12df49717580aba7b6107 554 SUPERFAMILY SSF47323 423 554 1.44E-35 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CU254_RS31400 a6bafa4959c12df49717580aba7b6107 554 SMART SM01016 4 93 4.8E-31 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CU254_RS31400 a6bafa4959c12df49717580aba7b6107 554 Gene3D G3DSA:3.30.1360.70 4 107 4.1E-29 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CU254_RS31400 a6bafa4959c12df49717580aba7b6107 554 Pfam PF00750 tRNA synthetases class I (R) 233 390 2.4E-10 T 28-03-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 CU254_RS31400 a6bafa4959c12df49717580aba7b6107 554 Pfam PF05746 DALR anticodon binding domain 429 554 2.4E-35 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CU254_RS31400 a6bafa4959c12df49717580aba7b6107 554 SMART SM00836 429 554 1.7E-57 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CU254_RS31400 a6bafa4959c12df49717580aba7b6107 554 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 31 554 2.6E-118 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CU254_RS31400 a6bafa4959c12df49717580aba7b6107 554 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 132 141 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CU254_RS31400 a6bafa4959c12df49717580aba7b6107 554 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 24 93 3.2E-21 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CU254_RS31400 a6bafa4959c12df49717580aba7b6107 554 Gene3D G3DSA:1.10.730.10 396 554 3.4E-51 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CU254_RS31400 a6bafa4959c12df49717580aba7b6107 554 Hamap MF_00123 Arginine--tRNA ligase [argS]. 8 554 25.373 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CU254_RS31400 a6bafa4959c12df49717580aba7b6107 554 PRINTS PR01038 Arginyl-tRNA synthetase signature 298 319 1.9E-22 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CU254_RS31400 a6bafa4959c12df49717580aba7b6107 554 PRINTS PR01038 Arginyl-tRNA synthetase signature 137 153 1.9E-22 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CU254_RS31400 a6bafa4959c12df49717580aba7b6107 554 PRINTS PR01038 Arginyl-tRNA synthetase signature 161 174 1.9E-22 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CU254_RS31400 a6bafa4959c12df49717580aba7b6107 554 PRINTS PR01038 Arginyl-tRNA synthetase signature 122 137 1.9E-22 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CU254_RS31400 a6bafa4959c12df49717580aba7b6107 554 Gene3D G3DSA:3.40.50.620 108 356 3.2E-46 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS31400 a6bafa4959c12df49717580aba7b6107 554 SUPERFAMILY SSF55190 7 113 3.79E-21 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CU254_RS31400 a6bafa4959c12df49717580aba7b6107 554 SUPERFAMILY SSF52374 119 440 7.51E-78 T 28-03-2018 CU254_RS07140 d0562a76836c86af52590950bbeb11b6 225 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 11 223 33.909 T 28-03-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CU254_RS07140 d0562a76836c86af52590950bbeb11b6 225 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 61 70 - T 28-03-2018 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CU254_RS07140 d0562a76836c86af52590950bbeb11b6 225 SUPERFAMILY SSF52141 9 223 1.33E-73 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CU254_RS07140 d0562a76836c86af52590950bbeb11b6 225 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 13 216 2.1E-57 T 28-03-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CU254_RS07140 d0562a76836c86af52590950bbeb11b6 225 SMART SM00987 53 212 3.1E-31 T 28-03-2018 CU254_RS07140 d0562a76836c86af52590950bbeb11b6 225 Gene3D G3DSA:3.40.470.10 3 225 3.7E-80 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CU254_RS07140 d0562a76836c86af52590950bbeb11b6 225 SMART SM00986 53 212 3.1E-31 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CU254_RS07140 d0562a76836c86af52590950bbeb11b6 225 Pfam PF03167 Uracil DNA glycosylase superfamily 55 211 3.9E-17 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CU254_RS31335 83f1a8d82665bca0eb706c967b71cafa 245 SUPERFAMILY SSF53474 9 244 4.02E-41 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS31335 83f1a8d82665bca0eb706c967b71cafa 245 Gene3D G3DSA:3.40.50.1820 3 245 1.3E-37 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS31335 83f1a8d82665bca0eb706c967b71cafa 245 Pfam PF00561 alpha/beta hydrolase fold 36 231 1.4E-13 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS31335 83f1a8d82665bca0eb706c967b71cafa 245 PRINTS PR00111 Alpha/beta hydrolase fold signature 191 205 1.1E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS31335 83f1a8d82665bca0eb706c967b71cafa 245 PRINTS PR00111 Alpha/beta hydrolase fold signature 90 103 1.1E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS31335 83f1a8d82665bca0eb706c967b71cafa 245 PRINTS PR00111 Alpha/beta hydrolase fold signature 76 89 1.1E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS30435 5df78a6dabf74dd5d5e26b968eadd04f 102 Gene3D G3DSA:3.40.30.10 66 102 2.1E-5 T 28-03-2018 CU254_RS30435 5df78a6dabf74dd5d5e26b968eadd04f 102 TIGRFAM TIGR01068 thioredoxin: thioredoxin 3 99 7.7E-30 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CU254_RS30435 5df78a6dabf74dd5d5e26b968eadd04f 102 Pfam PF00085 Thioredoxin 2 99 3.5E-27 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 CU254_RS30435 5df78a6dabf74dd5d5e26b968eadd04f 102 PIRSF PIRSF000077 1 101 7.7E-34 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CU254_RS30435 5df78a6dabf74dd5d5e26b968eadd04f 102 ProSitePatterns PS00194 Thioredoxin family active site. 19 37 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CU254_RS30435 5df78a6dabf74dd5d5e26b968eadd04f 102 SUPERFAMILY SSF52833 2 101 2.23E-34 T 28-03-2018 IPR012336 Thioredoxin-like fold CU254_RS30435 5df78a6dabf74dd5d5e26b968eadd04f 102 PRINTS PR00421 Thioredoxin family signature 26 35 2.0E-7 T 28-03-2018 CU254_RS30435 5df78a6dabf74dd5d5e26b968eadd04f 102 PRINTS PR00421 Thioredoxin family signature 65 76 2.0E-7 T 28-03-2018 CU254_RS30435 5df78a6dabf74dd5d5e26b968eadd04f 102 PRINTS PR00421 Thioredoxin family signature 18 26 2.0E-7 T 28-03-2018 CU254_RS30435 5df78a6dabf74dd5d5e26b968eadd04f 102 Gene3D G3DSA:3.40.30.10 1 65 1.7E-23 T 28-03-2018 CU254_RS21250 6093a498f76faf4f8ad657c8913d9996 161 Gene3D G3DSA:1.10.287.1060 4 105 3.3E-10 T 28-03-2018 CU254_RS21250 6093a498f76faf4f8ad657c8913d9996 161 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 9 97 1.0E-9 T 28-03-2018 IPR022536 ESX-1 secretion-associated protein EspC GO:0009306 CU254_RS24575 d187c37a968e6242f32061737f46423b 287 Pfam PF03799 Cell division protein FtsQ 174 271 6.2E-9 T 28-03-2018 IPR005548 Cell division protein FtsQ/DivIB CU254_RS24575 d187c37a968e6242f32061737f46423b 287 Pfam PF08478 POTRA domain, FtsQ-type 93 160 3.2E-19 T 28-03-2018 IPR013685 POTRA domain, FtsQ-type CU254_RS37630 98aabd570cdd1e8b1193cc5f8e62e16d 296 SUPERFAMILY SSF51445 95 295 1.05E-57 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS37630 98aabd570cdd1e8b1193cc5f8e62e16d 296 Gene3D G3DSA:3.20.20.80 77 296 8.5E-58 T 28-03-2018 CU254_RS37630 98aabd570cdd1e8b1193cc5f8e62e16d 296 SMART SM00641 96 205 3.3E-39 T 28-03-2018 IPR018077 Glycoside hydrolase, family 25 subgroup CU254_RS37630 98aabd570cdd1e8b1193cc5f8e62e16d 296 Pfam PF01183 Glycosyl hydrolases family 25 99 277 5.0E-46 T 28-03-2018 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 CU254_RS38700 ea93fa26f66f46f34e804593664fb9b6 89 Pfam PF13560 Helix-turn-helix domain 16 75 1.4E-11 T 28-03-2018 CU254_RS38700 ea93fa26f66f46f34e804593664fb9b6 89 SMART SM00530 20 74 9.5E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS38700 ea93fa26f66f46f34e804593664fb9b6 89 SUPERFAMILY SSF47413 12 75 1.6E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS38700 ea93fa26f66f46f34e804593664fb9b6 89 Gene3D G3DSA:1.10.260.40 7 76 9.3E-15 T 28-03-2018 CU254_RS24345 dbd64f0d63dfa71b69d4bbf00a04f7e1 342 Gene3D G3DSA:3.20.20.100 15 332 3.8E-85 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS24345 dbd64f0d63dfa71b69d4bbf00a04f7e1 342 SUPERFAMILY SSF51430 13 327 2.1E-89 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS24345 dbd64f0d63dfa71b69d4bbf00a04f7e1 342 Pfam PF00248 Aldo/keto reductase family 28 327 5.8E-67 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS05250 baa6b60a562e65d3028db3e0867a2b22 416 Gene3D G3DSA:1.20.1250.20 6 204 3.2E-15 T 28-03-2018 CU254_RS05250 baa6b60a562e65d3028db3e0867a2b22 416 Gene3D G3DSA:1.20.1250.20 209 400 9.5E-8 T 28-03-2018 CU254_RS05250 baa6b60a562e65d3028db3e0867a2b22 416 Pfam PF07690 Major Facilitator Superfamily 20 234 4.9E-15 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS05250 baa6b60a562e65d3028db3e0867a2b22 416 SUPERFAMILY SSF103473 17 392 8.89E-29 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS35465 5fc9f3d18cb8e33a809b763fbc08f532 538 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 75 502 55.251 T 28-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CU254_RS35465 5fc9f3d18cb8e33a809b763fbc08f532 538 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 76 499 7.7E-209 T 28-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CU254_RS35465 5fc9f3d18cb8e33a809b763fbc08f532 538 Pfam PF01964 Radical SAM ThiC family 76 496 2.3E-199 T 28-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CU254_RS35465 5fc9f3d18cb8e33a809b763fbc08f532 538 Pfam PF13667 ThiC-associated domain 10 73 1.9E-16 T 28-03-2018 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CU254_RS00290 56b675386b1118a0810e42a643da0bc2 233 Gene3D G3DSA:3.40.50.410 10 204 3.0E-19 T 28-03-2018 IPR002035 von Willebrand factor, type A CU254_RS00290 56b675386b1118a0810e42a643da0bc2 233 Pfam PF13519 von Willebrand factor type A domain 15 138 1.2E-6 T 28-03-2018 IPR002035 von Willebrand factor, type A CU254_RS00290 56b675386b1118a0810e42a643da0bc2 233 SMART SM00327 12 227 0.0064 T 28-03-2018 IPR002035 von Willebrand factor, type A CU254_RS00290 56b675386b1118a0810e42a643da0bc2 233 SUPERFAMILY SSF53300 11 151 6.68E-18 T 28-03-2018 IPR002035 von Willebrand factor, type A CU254_RS20710 9f1913963587fe5939f1979372999f4a 439 Pfam PF14863 Alkyl sulfatase dimerisation 279 414 9.9E-32 T 28-03-2018 IPR029228 Alkyl sulfatase dimerisation domain GO:0046983 CU254_RS20710 9f1913963587fe5939f1979372999f4a 439 Gene3D G3DSA:3.60.15.10 21 268 1.9E-27 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS20710 9f1913963587fe5939f1979372999f4a 439 Pfam PF00753 Metallo-beta-lactamase superfamily 44 242 7.2E-13 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS20710 9f1913963587fe5939f1979372999f4a 439 SMART SM00849 44 242 1.9E-8 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS20710 9f1913963587fe5939f1979372999f4a 439 SUPERFAMILY SSF56281 29 414 1.6E-81 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS30670 4b22ccfd7c47735d5909a06c6f3ee04a 170 Gene3D G3DSA:3.30.530.20 6 170 3.1E-27 T 28-03-2018 IPR023393 START-like domain CU254_RS30670 4b22ccfd7c47735d5909a06c6f3ee04a 170 SUPERFAMILY SSF55961 12 168 8.65E-21 T 28-03-2018 CU254_RS30670 4b22ccfd7c47735d5909a06c6f3ee04a 170 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 13 136 2.6E-13 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase CU254_RS33900 dfa01c7685c7b92e7ae849dc87ddbdad 522 Pfam PF16192 C-terminal four TMM region of protein-O-mannosyltransferase 337 521 3.2E-18 T 28-03-2018 IPR032421 Protein O-mannosyl-transferase, C-terminal four TM domain KEGG: 00500+2.4.1.10|KEGG: 00514+2.4.1.109|KEGG: 00515+2.4.1.109|MetaCyc: PWY-822|Reactome: R-HSA-5173105 CU254_RS33900 dfa01c7685c7b92e7ae849dc87ddbdad 522 Pfam PF02366 Dolichyl-phosphate-mannose-protein mannosyltransferase 120 297 4.7E-10 T 28-03-2018 IPR003342 Glycosyl transferase family 39/83 GO:0000030|GO:0006493|GO:0016020 Reactome: R-HSA-5173105 CU254_RS11120 454e8864834d700e64e5663787b544d2 142 Gene3D G3DSA:2.170.150.20 5 142 1.0E-57 T 28-03-2018 CU254_RS11120 454e8864834d700e64e5663787b544d2 142 Pfam PF01641 SelR domain 17 137 1.2E-52 T 28-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CU254_RS11120 454e8864834d700e64e5663787b544d2 142 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 13 139 2.1E-49 T 28-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CU254_RS11120 454e8864834d700e64e5663787b544d2 142 SUPERFAMILY SSF51316 12 139 1.36E-55 T 28-03-2018 IPR011057 Mss4-like CU254_RS15325 a30845b75ec08af5b825d73e6f73fe8e 268 Gene3D G3DSA:1.10.12.10 219 266 2.0E-14 T 28-03-2018 IPR014748 Crontonase, C-terminal CU254_RS15325 a30845b75ec08af5b825d73e6f73fe8e 268 SUPERFAMILY SSF52096 5 261 8.71E-61 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS15325 a30845b75ec08af5b825d73e6f73fe8e 268 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 103 123 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CU254_RS15325 a30845b75ec08af5b825d73e6f73fe8e 268 Gene3D G3DSA:3.90.226.10 6 218 9.8E-48 T 28-03-2018 CU254_RS15325 a30845b75ec08af5b825d73e6f73fe8e 268 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 261 3.6E-41 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CU254_RS04980 bffcb7613f9d7650301005bbc6a63dae 379 Gene3D G3DSA:3.50.50.60 5 330 8.9E-49 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS04980 bffcb7613f9d7650301005bbc6a63dae 379 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 310 326 1.5E-18 T 28-03-2018 CU254_RS04980 bffcb7613f9d7650301005bbc6a63dae 379 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 263 278 1.5E-18 T 28-03-2018 CU254_RS04980 bffcb7613f9d7650301005bbc6a63dae 379 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 1.5E-18 T 28-03-2018 CU254_RS04980 bffcb7613f9d7650301005bbc6a63dae 379 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 140 155 1.5E-18 T 28-03-2018 CU254_RS04980 bffcb7613f9d7650301005bbc6a63dae 379 Pfam PF01494 FAD binding domain 137 323 3.1E-14 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CU254_RS04980 bffcb7613f9d7650301005bbc6a63dae 379 Pfam PF00070 Pyridine nucleotide-disulphide oxidoreductase 6 65 9.3E-6 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS04980 bffcb7613f9d7650301005bbc6a63dae 379 SUPERFAMILY SSF51905 250 350 3.63E-54 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS04980 bffcb7613f9d7650301005bbc6a63dae 379 SUPERFAMILY SSF51905 6 161 3.63E-54 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS40080 b2614498210c74d0c7228e0a9dc90699 208 ProSitePatterns PS00622 LuxR-type HTH domain signature. 163 190 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS40080 b2614498210c74d0c7228e0a9dc90699 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 2.4E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS40080 b2614498210c74d0c7228e0a9dc90699 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 2.4E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS40080 b2614498210c74d0c7228e0a9dc90699 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 2.4E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS40080 b2614498210c74d0c7228e0a9dc90699 208 SUPERFAMILY SSF52172 1 131 4.84E-31 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS40080 b2614498210c74d0c7228e0a9dc90699 208 SMART SM00448 3 116 2.5E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS40080 b2614498210c74d0c7228e0a9dc90699 208 Gene3D G3DSA:3.40.50.2300 2 127 1.9E-32 T 28-03-2018 CU254_RS40080 b2614498210c74d0c7228e0a9dc90699 208 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 202 1.5E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS40080 b2614498210c74d0c7228e0a9dc90699 208 SMART SM00421 146 203 3.3E-26 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS40080 b2614498210c74d0c7228e0a9dc90699 208 SUPERFAMILY SSF46894 138 207 2.14E-21 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS40080 b2614498210c74d0c7228e0a9dc90699 208 Gene3D G3DSA:1.10.10.10 128 208 3.7E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS40080 b2614498210c74d0c7228e0a9dc90699 208 Pfam PF00072 Response regulator receiver domain 5 116 3.1E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS09470 5e5dc7f135f101e1d0db7a63ad6c40dc 295 SUPERFAMILY SSF51730 3 290 2.55E-89 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like CU254_RS09470 5e5dc7f135f101e1d0db7a63ad6c40dc 295 Gene3D G3DSA:3.20.20.220 1 295 7.4E-94 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like CU254_RS09470 5e5dc7f135f101e1d0db7a63ad6c40dc 295 Pfam PF02219 Methylenetetrahydrofolate reductase 11 288 9.0E-87 T 28-03-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CU254_RS03970 6031993b22665d3bfeac2a480a8bcc74 300 SUPERFAMILY SSF53474 12 295 1.09E-53 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS03970 6031993b22665d3bfeac2a480a8bcc74 300 Pfam PF12146 Serine aminopeptidase, S33 36 285 1.5E-23 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 CU254_RS03970 6031993b22665d3bfeac2a480a8bcc74 300 Gene3D G3DSA:3.40.50.1820 10 298 2.0E-49 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS13450 4b824431ae7d2ccfc15730c5d02abe00 309 PIRSF PIRSF001365 1 309 8.6E-66 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CU254_RS13450 4b824431ae7d2ccfc15730c5d02abe00 309 PRINTS PR00146 Dihydrodipicolinate synthase signature 107 123 1.1E-5 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CU254_RS13450 4b824431ae7d2ccfc15730c5d02abe00 309 PRINTS PR00146 Dihydrodipicolinate synthase signature 132 149 1.1E-5 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CU254_RS13450 4b824431ae7d2ccfc15730c5d02abe00 309 PRINTS PR00146 Dihydrodipicolinate synthase signature 39 60 1.1E-5 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CU254_RS13450 4b824431ae7d2ccfc15730c5d02abe00 309 SMART SM01130 5 307 1.3E-80 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CU254_RS13450 4b824431ae7d2ccfc15730c5d02abe00 309 Pfam PF00701 Dihydrodipicolinate synthetase family 6 303 5.6E-45 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CU254_RS13450 4b824431ae7d2ccfc15730c5d02abe00 309 Gene3D G3DSA:3.20.20.70 2 309 3.1E-75 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS13450 4b824431ae7d2ccfc15730c5d02abe00 309 SUPERFAMILY SSF51569 2 309 4.5E-72 T 28-03-2018 CU254_RS13450 4b824431ae7d2ccfc15730c5d02abe00 309 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 137 167 - T 28-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 CU254_RS05595 65bf6a618751049811e4d44995a847ab 444 Gene3D G3DSA:3.40.640.10 66 311 3.0E-48 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS05595 65bf6a618751049811e4d44995a847ab 444 SUPERFAMILY SSF53383 4 438 2.64E-77 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS05595 65bf6a618751049811e4d44995a847ab 444 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 69 362 7.2E-22 T 28-03-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 CU254_RS05595 65bf6a618751049811e4d44995a847ab 444 Gene3D G3DSA:3.90.1150.10 312 444 5.0E-9 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS07525 9fa076eb20faf00c14081c9ca0030ba9 101 SUPERFAMILY SSF89360 1 88 1.61E-9 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CU254_RS07525 9fa076eb20faf00c14081c9ca0030ba9 101 Gene3D G3DSA:2.60.300.12 1 101 7.1E-14 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CU254_RS16040 9f0bb1e446bf0230d5da94d7fdbe50f1 178 Gene3D G3DSA:3.40.390.10 34 165 5.9E-16 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CU254_RS16040 9f0bb1e446bf0230d5da94d7fdbe50f1 178 PIRSF PIRSF016573 10 174 1.2E-44 T 28-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 CU254_RS16040 9f0bb1e446bf0230d5da94d7fdbe50f1 178 SUPERFAMILY SSF55486 37 158 1.02E-22 T 28-03-2018 CU254_RS16040 9f0bb1e446bf0230d5da94d7fdbe50f1 178 Pfam PF02031 Streptomyces extracellular neutral proteinase (M7) family 34 165 1.6E-37 T 28-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 CU254_RS16040 9f0bb1e446bf0230d5da94d7fdbe50f1 178 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 123 147 5.2E-24 T 28-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 CU254_RS16040 9f0bb1e446bf0230d5da94d7fdbe50f1 178 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 150 164 5.2E-24 T 28-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 CU254_RS16040 9f0bb1e446bf0230d5da94d7fdbe50f1 178 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 41 67 5.2E-24 T 28-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 CU254_RS16040 9f0bb1e446bf0230d5da94d7fdbe50f1 178 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 98 122 5.2E-24 T 28-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 CU254_RS16040 9f0bb1e446bf0230d5da94d7fdbe50f1 178 ProDom PD016028 PROTEASE METALLOPROTEASE EXTRACELLULAR NEUTRAL SMALL METAL-BINDING ZINC HYDROLASE SNAPALYSIN ZYMOGEN 42 165 8.0E-31 T 28-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 CU254_RS19905 d4a6ec021c5f48ac22b10f21ef74220e 277 Pfam PF12833 Helix-turn-helix domain 161 246 4.1E-11 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS19905 d4a6ec021c5f48ac22b10f21ef74220e 277 Gene3D G3DSA:1.10.10.60 198 273 1.7E-6 T 28-03-2018 CU254_RS19905 d4a6ec021c5f48ac22b10f21ef74220e 277 Gene3D G3DSA:1.10.10.60 79 194 1.2E-6 T 28-03-2018 CU254_RS19905 d4a6ec021c5f48ac22b10f21ef74220e 277 SMART SM00342 155 246 3.7E-8 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS34635 a3a36a9c8ebf371ec98758226f4bee75 208 SUPERFAMILY SSF51197 12 205 1.92E-45 T 28-03-2018 CU254_RS34635 a3a36a9c8ebf371ec98758226f4bee75 208 Gene3D G3DSA:2.60.120.590 8 207 2.7E-45 T 28-03-2018 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like CU254_RS34635 a3a36a9c8ebf371ec98758226f4bee75 208 Pfam PF13532 2OG-Fe(II) oxygenase superfamily 15 204 7.0E-47 T 28-03-2018 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like CU254_RS00295 96c2edc4f204124a597dc4fce2b0e672 314 SUPERFAMILY SSF56112 9 290 1.3E-28 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS00295 96c2edc4f204124a597dc4fce2b0e672 314 Gene3D G3DSA:1.10.510.10 5 296 1.1E-28 T 28-03-2018 CU254_RS00295 96c2edc4f204124a597dc4fce2b0e672 314 Pfam PF00069 Protein kinase domain 23 285 1.7E-19 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CU254_RS00295 96c2edc4f204124a597dc4fce2b0e672 314 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 143 155 - T 28-03-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 CU254_RS00295 96c2edc4f204124a597dc4fce2b0e672 314 SMART SM00220 10 295 5.9E-10 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CU254_RS31035 47cde3594f68951e644e404278288b89 683 Gene3D G3DSA:3.40.50.300 25 442 1.0E-27 T 28-03-2018 CU254_RS31035 47cde3594f68951e644e404278288b89 683 Gene3D G3DSA:3.40.50.300 492 676 1.1E-8 T 28-03-2018 CU254_RS31035 47cde3594f68951e644e404278288b89 683 Pfam PF13307 Helicase C-terminal domain 503 660 2.2E-25 T 28-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CU254_RS31035 47cde3594f68951e644e404278288b89 683 SMART SM00491 518 647 7.7E-42 T 28-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CU254_RS31035 47cde3594f68951e644e404278288b89 683 Pfam PF00270 DEAD/DEAH box helicase 38 91 5.4E-6 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CU254_RS31035 47cde3594f68951e644e404278288b89 683 SUPERFAMILY SSF52540 39 93 8.89E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS31035 47cde3594f68951e644e404278288b89 683 SUPERFAMILY SSF52540 406 420 8.89E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS31035 47cde3594f68951e644e404278288b89 683 SUPERFAMILY SSF52540 483 641 8.89E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS31035 47cde3594f68951e644e404278288b89 683 SUPERFAMILY SSF52540 194 269 8.89E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS31035 47cde3594f68951e644e404278288b89 683 SMART SM00487 21 286 6.1E-5 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CU254_RS07270 41c7b134888b4612f32f8841301f3b10 333 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 12 293 1.9E-66 T 28-03-2018 IPR005693 Virulence factor Mce protein CU254_RS07270 41c7b134888b4612f32f8841301f3b10 333 Gene3D G3DSA:1.20.120.570 137 299 1.7E-4 T 28-03-2018 CU254_RS07270 41c7b134888b4612f32f8841301f3b10 333 Pfam PF02470 MlaD protein 38 111 7.2E-13 T 28-03-2018 IPR003399 Mce/MlaD CU254_RS18700 a41952fbeb6516d64778508b569482be 382 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 121 133 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CU254_RS18700 a41952fbeb6516d64778508b569482be 382 Gene3D G3DSA:1.10.540.10 1 119 3.7E-32 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS18700 a41952fbeb6516d64778508b569482be 382 SUPERFAMILY SSF56645 2 239 6.15E-67 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS18700 a41952fbeb6516d64778508b569482be 382 Gene3D G3DSA:1.20.140.10 216 381 7.5E-55 T 28-03-2018 CU254_RS18700 a41952fbeb6516d64778508b569482be 382 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 4 114 5.7E-28 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS18700 a41952fbeb6516d64778508b569482be 382 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 228 376 5.3E-48 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS18700 a41952fbeb6516d64778508b569482be 382 Gene3D G3DSA:2.40.110.10 120 215 9.8E-30 T 28-03-2018 CU254_RS18700 a41952fbeb6516d64778508b569482be 382 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 120 213 5.2E-24 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CU254_RS18700 a41952fbeb6516d64778508b569482be 382 SUPERFAMILY SSF47203 227 378 7.09E-54 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS18700 a41952fbeb6516d64778508b569482be 382 PIRSF PIRSF016578 1 381 6.2E-25 T 28-03-2018 CU254_RS21575 babf64487775cc0e02a35b12f8722ac3 413 SUPERFAMILY SSF51905 2 174 1.61E-61 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS21575 babf64487775cc0e02a35b12f8722ac3 413 SUPERFAMILY SSF51905 284 361 1.61E-61 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS21575 babf64487775cc0e02a35b12f8722ac3 413 Pfam PF01494 FAD binding domain 1 357 1.9E-27 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CU254_RS21575 babf64487775cc0e02a35b12f8722ac3 413 Gene3D G3DSA:3.50.50.60 1 362 6.0E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS21575 babf64487775cc0e02a35b12f8722ac3 413 SUPERFAMILY SSF54373 179 288 4.51E-26 T 28-03-2018 CU254_RS21575 babf64487775cc0e02a35b12f8722ac3 413 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 297 312 7.9E-20 T 28-03-2018 CU254_RS21575 babf64487775cc0e02a35b12f8722ac3 413 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 312 328 7.9E-20 T 28-03-2018 CU254_RS21575 babf64487775cc0e02a35b12f8722ac3 413 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 153 168 7.9E-20 T 28-03-2018 CU254_RS21575 babf64487775cc0e02a35b12f8722ac3 413 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 7.9E-20 T 28-03-2018 CU254_RS00760 d4c8848ea7ac04b57965ae303f54fd01 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 6.7E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS00760 d4c8848ea7ac04b57965ae303f54fd01 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 6.7E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS00760 d4c8848ea7ac04b57965ae303f54fd01 196 Gene3D G3DSA:1.10.260.40 41 60 7.0E-5 T 28-03-2018 CU254_RS00760 d4c8848ea7ac04b57965ae303f54fd01 196 Gene3D G3DSA:1.10.10.60 2 40 4.7E-12 T 28-03-2018 CU254_RS00760 d4c8848ea7ac04b57965ae303f54fd01 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 58 1.4E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS00760 d4c8848ea7ac04b57965ae303f54fd01 196 SUPERFAMILY SSF48498 77 169 9.39E-13 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS00760 d4c8848ea7ac04b57965ae303f54fd01 196 SUPERFAMILY SSF46689 3 74 6.16E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS00760 d4c8848ea7ac04b57965ae303f54fd01 196 Gene3D G3DSA:1.10.357.10 122 193 0.0087 T 28-03-2018 CU254_RS00760 d4c8848ea7ac04b57965ae303f54fd01 196 Gene3D G3DSA:1.10.357.10 61 121 9.0E-9 T 28-03-2018 CU254_RS41420 517bf7ed8ee4cf271f6feb44eed20a30 275 SUPERFAMILY SSF51658 50 273 1.9E-29 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CU254_RS41420 517bf7ed8ee4cf271f6feb44eed20a30 275 Pfam PF01261 Xylose isomerase-like TIM barrel 55 240 1.9E-22 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CU254_RS41420 517bf7ed8ee4cf271f6feb44eed20a30 275 Gene3D G3DSA:3.20.20.150 30 275 5.1E-30 T 28-03-2018 CU254_RS05145 b9d349981805c02c698aa8112bbfcdce 64 Gene3D G3DSA:3.30.70.20 1 64 8.5E-10 T 28-03-2018 CU254_RS05145 b9d349981805c02c698aa8112bbfcdce 64 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 2.2E-7 T 28-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CU254_RS05145 b9d349981805c02c698aa8112bbfcdce 64 PRINTS PR00352 3Fe-4S ferredoxin signature 48 60 2.2E-7 T 28-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CU254_RS05145 b9d349981805c02c698aa8112bbfcdce 64 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 2.2E-7 T 28-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CU254_RS05145 b9d349981805c02c698aa8112bbfcdce 64 SUPERFAMILY SSF54862 2 61 5.49E-14 T 28-03-2018 CU254_RS05145 b9d349981805c02c698aa8112bbfcdce 64 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 5 62 3.3E-15 T 28-03-2018 CU254_RS14235 a19349aca168ee07f497baf5845dfc48 1087 Gene3D G3DSA:3.40.50.300 616 1049 1.4E-19 T 28-03-2018 CU254_RS14235 a19349aca168ee07f497baf5845dfc48 1087 Pfam PF01935 Domain of unknown function DUF87 679 927 1.4E-8 T 28-03-2018 IPR002789 Helicase HerA, central domain CU254_RS14235 a19349aca168ee07f497baf5845dfc48 1087 SMART SM00382 695 1048 0.0052 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS14235 a19349aca168ee07f497baf5845dfc48 1087 SUPERFAMILY SSF52540 662 1025 3.81E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS14235 a19349aca168ee07f497baf5845dfc48 1087 Gene3D G3DSA:3.40.50.300 29 286 9.5E-4 T 28-03-2018 CU254_RS12335 aa2eb23ae1bc558641789e6efbab31d5 172 SMART SM00903 17 159 4.4E-52 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CU254_RS12335 aa2eb23ae1bc558641789e6efbab31d5 172 Gene3D G3DSA:2.30.110.10 5 170 2.1E-44 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS12335 aa2eb23ae1bc558641789e6efbab31d5 172 SUPERFAMILY SSF50475 13 162 2.8E-47 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS12335 aa2eb23ae1bc558641789e6efbab31d5 172 Pfam PF01613 Flavin reductase like domain 17 160 1.5E-37 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CU254_RS23980 ad8f3a21bc60eab5fd8e63777572e338 256 SUPERFAMILY SSF51735 9 243 5.0E-69 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS23980 ad8f3a21bc60eab5fd8e63777572e338 256 Gene3D G3DSA:3.40.50.720 2 251 3.4E-65 T 28-03-2018 CU254_RS23980 ad8f3a21bc60eab5fd8e63777572e338 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS23980 ad8f3a21bc60eab5fd8e63777572e338 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 2.4E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23980 ad8f3a21bc60eab5fd8e63777572e338 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 2.4E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23980 ad8f3a21bc60eab5fd8e63777572e338 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 2.4E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23980 ad8f3a21bc60eab5fd8e63777572e338 256 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 10 178 3.4E-4 T 28-03-2018 CU254_RS23980 ad8f3a21bc60eab5fd8e63777572e338 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 243 4.7E-54 T 28-03-2018 CU254_RS23980 ad8f3a21bc60eab5fd8e63777572e338 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 1.4E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23980 ad8f3a21bc60eab5fd8e63777572e338 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 1.4E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23980 ad8f3a21bc60eab5fd8e63777572e338 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.4E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23980 ad8f3a21bc60eab5fd8e63777572e338 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.4E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23980 ad8f3a21bc60eab5fd8e63777572e338 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 1.4E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23980 ad8f3a21bc60eab5fd8e63777572e338 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.4E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS00010 dce69e795d32639da4a8206fd7325a98 201 Gene3D G3DSA:1.10.1740.10 19 118 7.0E-18 T 28-03-2018 CU254_RS00010 dce69e795d32639da4a8206fd7325a98 201 Pfam PF04542 Sigma-70 region 2 40 101 3.1E-9 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS00010 dce69e795d32639da4a8206fd7325a98 201 Gene3D G3DSA:1.10.10.10 119 200 6.5E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS00010 dce69e795d32639da4a8206fd7325a98 201 SUPERFAMILY SSF88946 24 125 4.71E-18 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS00010 dce69e795d32639da4a8206fd7325a98 201 SUPERFAMILY SSF88659 126 194 1.85E-6 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS00010 dce69e795d32639da4a8206fd7325a98 201 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 36 192 1.3E-20 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS27950 481d405be21d48b00adfe80c71ba08b4 868 TIGRFAM TIGR03550 F420_cofG: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofG subunit 72 396 3.7E-147 T 28-03-2018 IPR019939 CofG family GO:0009108|GO:0016765|GO:0051539 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 CU254_RS27950 481d405be21d48b00adfe80c71ba08b4 868 SUPERFAMILY SSF102114 488 832 1.27E-43 T 28-03-2018 CU254_RS27950 481d405be21d48b00adfe80c71ba08b4 868 SUPERFAMILY SSF102114 30 373 1.57E-39 T 28-03-2018 CU254_RS27950 481d405be21d48b00adfe80c71ba08b4 868 Hamap MF_01612 FO synthase subunit 2 [cofH]. 476 841 46.963 T 28-03-2018 IPR019940 CofH family GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 CU254_RS27950 481d405be21d48b00adfe80c71ba08b4 868 SMART SM00729 75 308 3.0E-7 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CU254_RS27950 481d405be21d48b00adfe80c71ba08b4 868 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 524 837 8.0E-106 T 28-03-2018 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 CU254_RS27950 481d405be21d48b00adfe80c71ba08b4 868 Gene3D G3DSA:3.20.20.70 9 381 2.3E-38 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS27950 481d405be21d48b00adfe80c71ba08b4 868 Gene3D G3DSA:3.20.20.70 468 840 2.3E-48 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS27950 481d405be21d48b00adfe80c71ba08b4 868 Hamap MF_01611 FO synthase subunit 1 [cofG]. 71 398 50.228 T 28-03-2018 IPR019939 CofG family GO:0009108|GO:0016765|GO:0051539 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 CU254_RS27950 481d405be21d48b00adfe80c71ba08b4 868 Pfam PF04055 Radical SAM superfamily 532 705 5.0E-13 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CU254_RS27950 481d405be21d48b00adfe80c71ba08b4 868 Pfam PF04055 Radical SAM superfamily 79 257 7.1E-13 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CU254_RS27950 481d405be21d48b00adfe80c71ba08b4 868 TIGRFAM TIGR03551 F420_cofH: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofH subunit 490 838 4.7E-152 T 28-03-2018 IPR019940 CofH family GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 CU254_RS31685 9921d81ea67c22db2a4d5fb6fad96af8 244 SMART SM00345 7 66 5.5E-21 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS31685 9921d81ea67c22db2a4d5fb6fad96af8 244 Gene3D G3DSA:1.10.10.10 1 68 1.1E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS31685 9921d81ea67c22db2a4d5fb6fad96af8 244 Gene3D G3DSA:3.40.1410.10 69 232 2.5E-31 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CU254_RS31685 9921d81ea67c22db2a4d5fb6fad96af8 244 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 56 6.9E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS31685 9921d81ea67c22db2a4d5fb6fad96af8 244 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 26 40 6.9E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS31685 9921d81ea67c22db2a4d5fb6fad96af8 244 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 66 3.9E-21 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS31685 9921d81ea67c22db2a4d5fb6fad96af8 244 SUPERFAMILY SSF64288 55 230 3.61E-37 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CU254_RS31685 9921d81ea67c22db2a4d5fb6fad96af8 244 SUPERFAMILY SSF46785 2 70 6.82E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS31685 9921d81ea67c22db2a4d5fb6fad96af8 244 Pfam PF07702 UTRA domain 87 223 3.4E-24 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CU254_RS31685 9921d81ea67c22db2a4d5fb6fad96af8 244 SMART SM00866 87 226 4.8E-21 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CU254_RS30280 31dbd0d941f63f21e7fd6ecc54eefca0 439 Pfam PF00392 Bacterial regulatory proteins, gntR family 2 59 1.5E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS30280 31dbd0d941f63f21e7fd6ecc54eefca0 439 SUPERFAMILY SSF53383 81 438 1.51E-71 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS30280 31dbd0d941f63f21e7fd6ecc54eefca0 439 Pfam PF00155 Aminotransferase class I and II 95 381 1.3E-18 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CU254_RS30280 31dbd0d941f63f21e7fd6ecc54eefca0 439 Gene3D G3DSA:3.90.1150.10 327 439 7.7E-19 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS30280 31dbd0d941f63f21e7fd6ecc54eefca0 439 SUPERFAMILY SSF46785 2 63 3.22E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS30280 31dbd0d941f63f21e7fd6ecc54eefca0 439 Gene3D G3DSA:1.10.10.10 1 61 1.6E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS30280 31dbd0d941f63f21e7fd6ecc54eefca0 439 Gene3D G3DSA:3.40.640.10 95 326 8.2E-35 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS30280 31dbd0d941f63f21e7fd6ecc54eefca0 439 SMART SM00345 2 59 2.7E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS30280 31dbd0d941f63f21e7fd6ecc54eefca0 439 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 19 33 7.5E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS30280 31dbd0d941f63f21e7fd6ecc54eefca0 439 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 49 7.5E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS18825 7ac5e4e4e822400d787b8bdbeab4c8bc 306 Pfam PF03466 LysR substrate binding domain 90 293 7.3E-33 T 28-03-2018 IPR005119 LysR, substrate-binding CU254_RS18825 7ac5e4e4e822400d787b8bdbeab4c8bc 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 6.6E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS18825 7ac5e4e4e822400d787b8bdbeab4c8bc 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 6.6E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS18825 7ac5e4e4e822400d787b8bdbeab4c8bc 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 6.6E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS18825 7ac5e4e4e822400d787b8bdbeab4c8bc 306 Gene3D G3DSA:3.40.190.10 178 268 4.3E-12 T 28-03-2018 CU254_RS18825 7ac5e4e4e822400d787b8bdbeab4c8bc 306 Gene3D G3DSA:1.10.10.10 1 83 2.6E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS18825 7ac5e4e4e822400d787b8bdbeab4c8bc 306 Gene3D G3DSA:3.40.190.10 90 177 2.9E-15 T 28-03-2018 CU254_RS18825 7ac5e4e4e822400d787b8bdbeab4c8bc 306 SUPERFAMILY SSF46785 2 85 1.4E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS18825 7ac5e4e4e822400d787b8bdbeab4c8bc 306 SUPERFAMILY SSF53850 94 297 1.09E-29 T 28-03-2018 CU254_RS18825 7ac5e4e4e822400d787b8bdbeab4c8bc 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 7.8E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS10540 eef6c09d27663b740a137b61c0e5c6d9 125 SUPERFAMILY SSF54593 1 124 6.88E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS10540 eef6c09d27663b740a137b61c0e5c6d9 125 Gene3D G3DSA:3.10.180.10 1 125 2.8E-19 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS21285 acdcdd177be97c15764be0cd93fd4b5b 750 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 20 125 1.0E-25 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CU254_RS21285 acdcdd177be97c15764be0cd93fd4b5b 750 Gene3D G3DSA:3.30.365.10 584 750 8.4E-42 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CU254_RS21285 acdcdd177be97c15764be0cd93fd4b5b 750 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 144 681 6.5E-156 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CU254_RS21285 acdcdd177be97c15764be0cd93fd4b5b 750 SUPERFAMILY SSF56003 118 746 2.88E-176 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CU254_RS21285 acdcdd177be97c15764be0cd93fd4b5b 750 SUPERFAMILY SSF54665 2 148 6.02E-38 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CU254_RS21285 acdcdd177be97c15764be0cd93fd4b5b 750 Gene3D G3DSA:3.30.365.10 159 262 7.3E-30 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CU254_RS21285 acdcdd177be97c15764be0cd93fd4b5b 750 Gene3D G3DSA:3.30.365.10 436 583 6.7E-38 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CU254_RS21285 acdcdd177be97c15764be0cd93fd4b5b 750 Gene3D G3DSA:3.30.365.10 263 425 1.5E-34 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CU254_RS21285 acdcdd177be97c15764be0cd93fd4b5b 750 Gene3D G3DSA:3.90.1170.50 2 126 7.1E-32 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CU254_RS21285 acdcdd177be97c15764be0cd93fd4b5b 750 SMART SM01008 18 126 2.8E-39 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CU254_RS25410 337e1672cff4e443852de5f971c25eda 501 SUPERFAMILY SSF50443 329 497 2.01E-67 T 28-03-2018 IPR004216 L-fucose/L-arabinose isomerase, C-terminal CU254_RS25410 337e1672cff4e443852de5f971c25eda 501 ProDom PD018364 ISOMERASE L-ARABINOSE ARABINOSE METABOLISM CARBOHYDRATE CATABOLISM ARAA 8 304 1.0E-104 T 28-03-2018 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4 CU254_RS25410 337e1672cff4e443852de5f971c25eda 501 PIRSF PIRSF001478 1 499 7.9E-224 T 28-03-2018 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4 CU254_RS25410 337e1672cff4e443852de5f971c25eda 501 Pfam PF11762 L-arabinose isomerase C-terminal domain 362 475 3.2E-47 T 28-03-2018 IPR024664 L-arabinose isomerase, C-terminal KEGG: 00040+5.3.1.4 CU254_RS25410 337e1672cff4e443852de5f971c25eda 501 Pfam PF02610 L-arabinose isomerase 6 359 7.2E-167 T 28-03-2018 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4 CU254_RS25410 337e1672cff4e443852de5f971c25eda 501 SUPERFAMILY SSF53743 1 325 2.88E-113 T 28-03-2018 IPR009015 L-fucose isomerase, N-terminal/central domain GO:0005737|GO:0005996|GO:0016861 CU254_RS25410 337e1672cff4e443852de5f971c25eda 501 Hamap MF_00519 L-arabinose isomerase [araA]. 1 476 62.523 T 28-03-2018 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4 CU254_RS09260 4a4c3b0ded7fa82b2c169180006a5be7 141 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 123 5.9E-5 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CU254_RS09260 4a4c3b0ded7fa82b2c169180006a5be7 141 SUPERFAMILY SSF54593 1 131 2.82E-27 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS09260 4a4c3b0ded7fa82b2c169180006a5be7 141 Gene3D G3DSA:3.10.180.10 3 140 1.3E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS32840 46993dbf4024744a0d9865c28dc8d373 419 Pfam PF00082 Subtilase family 148 351 3.6E-12 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS32840 46993dbf4024744a0d9865c28dc8d373 419 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 331 341 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CU254_RS32840 46993dbf4024744a0d9865c28dc8d373 419 SUPERFAMILY SSF52743 65 413 2.09E-54 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS32840 46993dbf4024744a0d9865c28dc8d373 419 Gene3D G3DSA:3.40.50.200 58 418 1.7E-35 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS14440 d739f0d80c385f555766636743d634f9 542 Pfam PF00501 AMP-binding enzyme 28 438 1.4E-76 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS14440 d739f0d80c385f555766636743d634f9 542 Gene3D G3DSA:3.40.50.980 191 341 2.2E-33 T 28-03-2018 CU254_RS14440 d739f0d80c385f555766636743d634f9 542 Gene3D G3DSA:2.30.38.10 342 432 1.5E-17 T 28-03-2018 CU254_RS14440 d739f0d80c385f555766636743d634f9 542 Gene3D G3DSA:3.30.300.30 435 542 1.6E-31 T 28-03-2018 CU254_RS14440 d739f0d80c385f555766636743d634f9 542 Pfam PF13193 AMP-binding enzyme C-terminal domain 448 526 5.9E-26 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS14440 d739f0d80c385f555766636743d634f9 542 SUPERFAMILY SSF56801 18 537 1.96E-138 T 28-03-2018 CU254_RS14440 d739f0d80c385f555766636743d634f9 542 Gene3D G3DSA:3.40.50.980 3 190 6.0E-36 T 28-03-2018 CU254_RS27150 fe3f356ea4e2ba131a49baf2bcfc3501 484 Gene3D G3DSA:2.30.40.10 2 99 3.3E-13 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS27150 fe3f356ea4e2ba131a49baf2bcfc3501 484 SUPERFAMILY SSF51556 171 435 4.09E-37 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS27150 fe3f356ea4e2ba131a49baf2bcfc3501 484 SUPERFAMILY SSF51556 53 114 4.09E-37 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS27150 fe3f356ea4e2ba131a49baf2bcfc3501 484 Pfam PF07969 Amidohydrolase family 42 482 1.6E-61 T 28-03-2018 IPR013108 Amidohydrolase 3 CU254_RS27150 fe3f356ea4e2ba131a49baf2bcfc3501 484 Gene3D G3DSA:3.20.20.140 155 448 4.0E-46 T 28-03-2018 CU254_RS27150 fe3f356ea4e2ba131a49baf2bcfc3501 484 SUPERFAMILY SSF51338 17 54 4.68E-9 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS27150 fe3f356ea4e2ba131a49baf2bcfc3501 484 SUPERFAMILY SSF51338 441 482 4.68E-9 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS07600 705d0d2d768bb8eb3a7743b9e5516395 174 SUPERFAMILY SSF47741 84 155 1.83E-34 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CU254_RS07600 705d0d2d768bb8eb3a7743b9e5516395 174 Gene3D G3DSA:3.10.20.30 1 74 4.1E-22 T 28-03-2018 IPR012675 Beta-grasp domain CU254_RS07600 705d0d2d768bb8eb3a7743b9e5516395 174 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 5 57 4.2E-6 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CU254_RS07600 705d0d2d768bb8eb3a7743b9e5516395 174 Gene3D G3DSA:1.10.150.120 75 171 4.4E-38 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CU254_RS07600 705d0d2d768bb8eb3a7743b9e5516395 174 SUPERFAMILY SSF54292 2 78 3.01E-22 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CU254_RS07600 705d0d2d768bb8eb3a7743b9e5516395 174 Pfam PF01799 [2Fe-2S] binding domain 73 145 1.5E-31 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CU254_RS30205 9b1f3afd490fcfe5e7cc36bb9ba405f0 214 Gene3D G3DSA:3.40.50.2300 1 128 2.4E-19 T 28-03-2018 CU254_RS30205 9b1f3afd490fcfe5e7cc36bb9ba405f0 214 SMART SM00421 143 200 6.1E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS30205 9b1f3afd490fcfe5e7cc36bb9ba405f0 214 Pfam PF00072 Response regulator receiver domain 2 105 8.7E-14 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS30205 9b1f3afd490fcfe5e7cc36bb9ba405f0 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 145 191 3.2E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS30205 9b1f3afd490fcfe5e7cc36bb9ba405f0 214 SMART SM00448 1 117 0.0052 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS30205 9b1f3afd490fcfe5e7cc36bb9ba405f0 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 146 160 2.1E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS30205 9b1f3afd490fcfe5e7cc36bb9ba405f0 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 188 2.1E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS30205 9b1f3afd490fcfe5e7cc36bb9ba405f0 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 176 2.1E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS30205 9b1f3afd490fcfe5e7cc36bb9ba405f0 214 SUPERFAMILY SSF52172 2 129 3.27E-17 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS30205 9b1f3afd490fcfe5e7cc36bb9ba405f0 214 Gene3D G3DSA:1.10.10.10 129 214 5.7E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS30205 9b1f3afd490fcfe5e7cc36bb9ba405f0 214 SUPERFAMILY SSF46894 134 191 6.46E-14 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS04920 3bd8ce29a985a6173c67ff3989c5a040 508 Gene3D G3DSA:1.20.200.10 199 508 1.2E-116 T 28-03-2018 CU254_RS04920 3bd8ce29a985a6173c67ff3989c5a040 508 Pfam PF00221 Aromatic amino acid lyase 13 472 7.7E-181 T 28-03-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 CU254_RS04920 3bd8ce29a985a6173c67ff3989c5a040 508 Gene3D G3DSA:1.10.275.10 3 198 3.2E-71 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal CU254_RS04920 3bd8ce29a985a6173c67ff3989c5a040 508 SUPERFAMILY SSF48557 3 501 3.45E-181 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 CU254_RS04920 3bd8ce29a985a6173c67ff3989c5a040 508 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 140 156 - T 28-03-2018 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 CU254_RS04920 3bd8ce29a985a6173c67ff3989c5a040 508 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 6 505 5.8E-198 T 28-03-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CU254_RS20605 af4079e87f9646e53a861c00a024b82d 98 Gene3D G3DSA:2.40.30.100 3 94 3.4E-28 T 28-03-2018 IPR015018 Protein of unknown function DUF1905 CU254_RS20605 af4079e87f9646e53a861c00a024b82d 98 SUPERFAMILY SSF141694 3 94 2.07E-19 T 28-03-2018 CU254_RS20605 af4079e87f9646e53a861c00a024b82d 98 Pfam PF08922 Domain of unknown function (DUF1905) 5 93 1.2E-28 T 28-03-2018 IPR015018 Protein of unknown function DUF1905 CU254_RS38975 cb2dabe49e71becdf413560e3a39875b 271 Pfam PF14011 EspG family 33 264 9.2E-35 T 28-03-2018 IPR025734 EspG family CU254_RS22325 477ff254e0e340893f581930bcb48a36 281 SUPERFAMILY SSF53474 15 280 6.95E-37 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS22325 477ff254e0e340893f581930bcb48a36 281 Pfam PF12697 Alpha/beta hydrolase family 33 275 7.4E-19 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS22325 477ff254e0e340893f581930bcb48a36 281 Gene3D G3DSA:3.40.50.1820 8 281 4.3E-35 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS00720 811d23b22bbc30be07b705ef59aa40d3 240 Gene3D G3DSA:1.10.1780.10 81 175 6.0E-21 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CU254_RS00720 811d23b22bbc30be07b705ef59aa40d3 240 Gene3D G3DSA:1.10.1780.10 176 239 3.3E-15 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CU254_RS00720 811d23b22bbc30be07b705ef59aa40d3 240 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 105 155 3.2E-12 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CU254_RS00720 811d23b22bbc30be07b705ef59aa40d3 240 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 183 231 4.7E-15 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CU254_RS00720 811d23b22bbc30be07b705ef59aa40d3 240 SUPERFAMILY SSF81923 93 229 1.47E-25 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CU254_RS19400 c7ba8a3c86c3d7427114ef79cf14d31c 175 Gene3D G3DSA:1.10.3300.10 2 174 8.7E-31 T 28-03-2018 IPR023286 ABATE domain CU254_RS19400 c7ba8a3c86c3d7427114ef79cf14d31c 175 Pfam PF11706 CGNR zinc finger 130 172 1.2E-16 T 28-03-2018 IPR021005 Zinc finger, CGNR CU254_RS19400 c7ba8a3c86c3d7427114ef79cf14d31c 175 SUPERFAMILY SSF160904 2 171 2.75E-35 T 28-03-2018 CU254_RS09245 29cb8b04f7d309540e1d6781d5ae9711 207 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 1 203 1.3E-63 T 28-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CU254_RS09245 29cb8b04f7d309540e1d6781d5ae9711 207 PIRSF PIRSF000495 1 207 1.3E-63 T 28-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CU254_RS09245 29cb8b04f7d309540e1d6781d5ae9711 207 SUPERFAMILY SSF52317 1 204 1.81E-53 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS09245 29cb8b04f7d309540e1d6781d5ae9711 207 Gene3D G3DSA:3.40.50.880 1 207 5.1E-48 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS09245 29cb8b04f7d309540e1d6781d5ae9711 207 Pfam PF00117 Glutamine amidotransferase class-I 3 201 1.2E-17 T 28-03-2018 IPR017926 Glutamine amidotransferase CU254_RS09245 29cb8b04f7d309540e1d6781d5ae9711 207 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 1 205 29.489 T 28-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CU254_RS19710 f76229bff48e7e249530c7ddad0e8677 141 Gene3D G3DSA:3.10.129.10 1 131 2.9E-23 T 28-03-2018 CU254_RS19710 f76229bff48e7e249530c7ddad0e8677 141 SUPERFAMILY SSF54637 3 140 7.79E-36 T 28-03-2018 IPR029069 HotDog domain CU254_RS19710 f76229bff48e7e249530c7ddad0e8677 141 Pfam PF13279 Thioesterase-like superfamily 8 124 3.9E-15 T 28-03-2018 CU254_RS15060 a3bfa6c52b9c2321a9bbf662150a2b3a 207 SUPERFAMILY SSF53335 10 193 4.34E-39 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS15060 a3bfa6c52b9c2321a9bbf662150a2b3a 207 Pfam PF08241 Methyltransferase domain 48 141 7.6E-23 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CU254_RS15060 a3bfa6c52b9c2321a9bbf662150a2b3a 207 Gene3D G3DSA:3.40.50.150 4 206 4.8E-32 T 28-03-2018 CU254_RS09570 235f5b667a3b0b5b7d427636aef76aa3 299 Pfam PF13560 Helix-turn-helix domain 14 70 6.0E-7 T 28-03-2018 CU254_RS09570 235f5b667a3b0b5b7d427636aef76aa3 299 Gene3D G3DSA:1.10.260.40 1 83 1.6E-8 T 28-03-2018 CU254_RS09570 235f5b667a3b0b5b7d427636aef76aa3 299 SUPERFAMILY SSF47413 12 67 2.03E-7 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS11750 28715fa58476e5c98ef4bdc02db08603 171 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 80 163 3.4E-21 T 28-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain CU254_RS11750 28715fa58476e5c98ef4bdc02db08603 171 SUPERFAMILY SSF54534 38 170 1.02E-28 T 28-03-2018 CU254_RS11750 28715fa58476e5c98ef4bdc02db08603 171 Gene3D G3DSA:3.10.50.40 32 170 2.0E-29 T 28-03-2018 CU254_RS32885 a3f2a252aab4b55d3ac20be7cc33794c 224 Pfam PF03006 Haemolysin-III related 16 215 2.2E-40 T 28-03-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 CU254_RS32885 a3f2a252aab4b55d3ac20be7cc33794c 224 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 17 221 4.3E-58 T 28-03-2018 IPR005744 Hly-III GO:0016021|GO:0019835 CU254_RS13700 17efb2acb9652ecd3ba31452dbc04328 188 Pfam PF14013 MT0933-like antitoxin protein 8 54 8.3E-18 T 28-03-2018 IPR028037 Antitoxin Rv0909/MT0933 CU254_RS19895 ec6e169044dbf757e7e36d40e248ecea 1111 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 2 53 9.5E-8 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS19895 ec6e169044dbf757e7e36d40e248ecea 1111 Gene3D G3DSA:2.40.40.20 607 786 9.2E-33 T 28-03-2018 CU254_RS19895 ec6e169044dbf757e7e36d40e248ecea 1111 Gene3D G3DSA:3.40.50.740 293 600 4.5E-39 T 28-03-2018 CU254_RS19895 ec6e169044dbf757e7e36d40e248ecea 1111 SUPERFAMILY SSF53706 3 648 1.44E-132 T 28-03-2018 CU254_RS19895 ec6e169044dbf757e7e36d40e248ecea 1111 Gene3D G3DSA:3.40.50.80 881 1014 1.1E-27 T 28-03-2018 CU254_RS19895 ec6e169044dbf757e7e36d40e248ecea 1111 Pfam PF01568 Molydopterin dinucleotide binding domain 646 766 8.3E-22 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CU254_RS19895 ec6e169044dbf757e7e36d40e248ecea 1111 Pfam PF00384 Molybdopterin oxidoreductase 57 549 3.8E-32 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS19895 ec6e169044dbf757e7e36d40e248ecea 1111 Gene3D G3DSA:3.40.50.740 59 292 8.9E-26 T 28-03-2018 CU254_RS19895 ec6e169044dbf757e7e36d40e248ecea 1111 Gene3D G3DSA:3.10.20.30 1015 1111 1.1E-16 T 28-03-2018 IPR012675 Beta-grasp domain CU254_RS19895 ec6e169044dbf757e7e36d40e248ecea 1111 Gene3D G3DSA:2.40.30.10 787 880 3.8E-21 T 28-03-2018 CU254_RS19895 ec6e169044dbf757e7e36d40e248ecea 1111 Pfam PF00970 Oxidoreductase FAD-binding domain 786 881 1.1E-7 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CU254_RS19895 ec6e169044dbf757e7e36d40e248ecea 1111 Pfam PF00175 Oxidoreductase NAD-binding domain 893 993 5.0E-11 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CU254_RS19895 ec6e169044dbf757e7e36d40e248ecea 1111 SMART SM00926 1 54 1.4E-12 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS19895 ec6e169044dbf757e7e36d40e248ecea 1111 Gene3D G3DSA:2.20.25.90 2 58 4.1E-13 T 28-03-2018 CU254_RS19895 ec6e169044dbf757e7e36d40e248ecea 1111 PRINTS PR00410 Phenol hydroxylase reductase family signature 813 825 5.9E-5 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CU254_RS19895 ec6e169044dbf757e7e36d40e248ecea 1111 PRINTS PR00410 Phenol hydroxylase reductase family signature 982 990 5.9E-5 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CU254_RS19895 ec6e169044dbf757e7e36d40e248ecea 1111 PRINTS PR00410 Phenol hydroxylase reductase family signature 892 911 5.9E-5 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CU254_RS19895 ec6e169044dbf757e7e36d40e248ecea 1111 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 1046 1104 5.1E-9 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CU254_RS19895 ec6e169044dbf757e7e36d40e248ecea 1111 SUPERFAMILY SSF54292 1005 1110 3.41E-19 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CU254_RS19895 ec6e169044dbf757e7e36d40e248ecea 1111 SUPERFAMILY SSF63380 779 881 2.87E-23 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CU254_RS19895 ec6e169044dbf757e7e36d40e248ecea 1111 SUPERFAMILY SSF52343 888 1016 1.96E-30 T 28-03-2018 CU254_RS19895 ec6e169044dbf757e7e36d40e248ecea 1111 SUPERFAMILY SSF50692 609 773 1.99E-30 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain CU254_RS23295 f77c1a0d29a90d320d900e81efb99c7e 318 SUPERFAMILY SSF102198 62 317 2.49E-19 T 28-03-2018 CU254_RS23295 f77c1a0d29a90d320d900e81efb99c7e 318 Pfam PF04199 Putative cyclase 64 249 1.6E-16 T 28-03-2018 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 CU254_RS23295 f77c1a0d29a90d320d900e81efb99c7e 318 Gene3D G3DSA:3.50.30.50 46 318 5.7E-45 T 28-03-2018 CU254_RS34070 3e93a63bbb6bd9a0b2dd7edc43af4509 179 SUPERFAMILY SSF51182 82 163 7.37E-19 T 28-03-2018 IPR011051 RmlC-like cupin domain CU254_RS34070 3e93a63bbb6bd9a0b2dd7edc43af4509 179 Gene3D G3DSA:1.10.260.40 1 68 4.0E-15 T 28-03-2018 CU254_RS34070 3e93a63bbb6bd9a0b2dd7edc43af4509 179 Pfam PF01381 Helix-turn-helix 12 66 8.0E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS34070 3e93a63bbb6bd9a0b2dd7edc43af4509 179 Gene3D G3DSA:2.60.120.10 69 177 1.1E-18 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS34070 3e93a63bbb6bd9a0b2dd7edc43af4509 179 Pfam PF07883 Cupin domain 106 165 2.2E-15 T 28-03-2018 IPR013096 Cupin 2, conserved barrel CU254_RS34070 3e93a63bbb6bd9a0b2dd7edc43af4509 179 SUPERFAMILY SSF47413 3 70 2.08E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS34070 3e93a63bbb6bd9a0b2dd7edc43af4509 179 SMART SM00530 11 66 2.2E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS01330 2cc0854e36780eff6a3f24ebe06f8970 229 SUPERFAMILY SSF53335 4 228 1.24E-39 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS01330 2cc0854e36780eff6a3f24ebe06f8970 229 Gene3D G3DSA:3.40.50.150 3 227 1.7E-32 T 28-03-2018 CU254_RS01330 2cc0854e36780eff6a3f24ebe06f8970 229 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 4 227 31.141 T 28-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 CU254_RS01330 2cc0854e36780eff6a3f24ebe06f8970 229 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 13 227 8.8E-63 T 28-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 CU254_RS01330 2cc0854e36780eff6a3f24ebe06f8970 229 Pfam PF01209 ubiE/COQ5 methyltransferase family 11 227 6.9E-51 T 28-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 CU254_RS01330 2cc0854e36780eff6a3f24ebe06f8970 229 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 135 149 - T 28-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 CU254_RS35165 9ddd0e9fd6842c10bc2b17706b1801e9 254 Gene3D G3DSA:3.10.310.10 122 242 1.8E-29 T 28-03-2018 CU254_RS35165 9ddd0e9fd6842c10bc2b17706b1801e9 254 SUPERFAMILY SSF54506 7 254 1.47E-70 T 28-03-2018 CU254_RS35165 9ddd0e9fd6842c10bc2b17706b1801e9 254 Gene3D G3DSA:3.10.310.10 4 121 9.8E-28 T 28-03-2018 CU254_RS35165 9ddd0e9fd6842c10bc2b17706b1801e9 254 Pfam PF02567 Phenazine biosynthesis-like protein 12 250 5.8E-57 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CU254_RS35165 9ddd0e9fd6842c10bc2b17706b1801e9 254 PIRSF PIRSF016184 5 254 1.0E-45 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CU254_RS35165 9ddd0e9fd6842c10bc2b17706b1801e9 254 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 7 87 2.4E-24 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CU254_RS06160 b27762ae687d3d714cdc789c5e3d6879 71 Gene3D G3DSA:2.40.50.140 2 71 1.2E-13 T 28-03-2018 CU254_RS06160 b27762ae687d3d714cdc789c5e3d6879 71 Pfam PF00313 'Cold-shock' DNA-binding domain 4 62 1.7E-9 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CU254_RS06160 b27762ae687d3d714cdc789c5e3d6879 71 SUPERFAMILY SSF50249 3 68 5.71E-9 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CU254_RS07695 f4361aa774609e3cca0bc6e449dead6b 613 Gene3D G3DSA:3.40.50.620 222 607 5.4E-59 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS07695 f4361aa774609e3cca0bc6e449dead6b 613 Pfam PF13537 Glutamine amidotransferase domain 48 169 2.3E-46 T 28-03-2018 IPR017932 Glutamine amidotransferase type 2 domain CU254_RS07695 f4361aa774609e3cca0bc6e449dead6b 613 PIRSF PIRSF001589 1 612 3.3E-138 T 28-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 CU254_RS07695 f4361aa774609e3cca0bc6e449dead6b 613 Pfam PF00733 Asparagine synthase 240 602 4.8E-83 T 28-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 CU254_RS07695 f4361aa774609e3cca0bc6e449dead6b 613 Gene3D G3DSA:3.60.20.10 1 221 1.3E-55 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CU254_RS07695 f4361aa774609e3cca0bc6e449dead6b 613 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 538 1.5E-149 T 28-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 CU254_RS07695 f4361aa774609e3cca0bc6e449dead6b 613 SUPERFAMILY SSF52402 229 396 3.03E-59 T 28-03-2018 CU254_RS07695 f4361aa774609e3cca0bc6e449dead6b 613 SUPERFAMILY SSF52402 458 576 3.03E-59 T 28-03-2018 CU254_RS07695 f4361aa774609e3cca0bc6e449dead6b 613 SUPERFAMILY SSF56235 1 224 5.32E-61 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CU254_RS17410 facd0c2bafc9cf036814c1a131cc4181 491 SUPERFAMILY SSF111283 14 487 2.22E-77 T 28-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 CU254_RS17410 facd0c2bafc9cf036814c1a131cc4181 491 Gene3D G3DSA:3.30.2290.10 13 226 1.5E-34 T 28-03-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal domain CU254_RS17410 facd0c2bafc9cf036814c1a131cc4181 491 Pfam PF01523 Putative modulator of DNA gyrase 33 336 5.3E-45 T 28-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 CU254_RS22600 ed4d2c444ad056f7c232bcdcf1601d73 133 Pfam PF01638 HxlR-like helix-turn-helix 32 118 1.4E-26 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type CU254_RS22600 ed4d2c444ad056f7c232bcdcf1601d73 133 Gene3D G3DSA:1.10.10.10 29 130 7.0E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS22600 ed4d2c444ad056f7c232bcdcf1601d73 133 SUPERFAMILY SSF46785 21 120 1.31E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS40455 c3772b6900b12edaa41e28900ebb2c7d 399 Gene3D G3DSA:3.90.1150.10 263 399 6.0E-15 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS40455 c3772b6900b12edaa41e28900ebb2c7d 399 Gene3D G3DSA:3.40.640.10 28 262 1.9E-33 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS40455 c3772b6900b12edaa41e28900ebb2c7d 399 Pfam PF00266 Aminotransferase class-V 21 391 6.4E-35 T 28-03-2018 IPR000192 Aminotransferase class V domain CU254_RS40455 c3772b6900b12edaa41e28900ebb2c7d 399 SUPERFAMILY SSF53383 3 398 1.67E-62 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS40455 c3772b6900b12edaa41e28900ebb2c7d 399 TIGRFAM TIGR01976 am_tr_V_VC1184: cysteine desulfurase family protein 3 395 1.1E-121 T 28-03-2018 IPR011340 Cysteine desulfurase-related CU254_RS19345 1ce349ee972df54299ff6b96eafaf950 371 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 117 195 1.8E-15 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CU254_RS19345 1ce349ee972df54299ff6b96eafaf950 371 Gene3D G3DSA:1.20.140.10 207 371 5.2E-31 T 28-03-2018 CU254_RS19345 1ce349ee972df54299ff6b96eafaf950 371 Gene3D G3DSA:1.10.540.10 2 115 2.7E-19 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS19345 1ce349ee972df54299ff6b96eafaf950 371 Gene3D G3DSA:2.40.110.10 116 206 3.9E-25 T 28-03-2018 CU254_RS19345 1ce349ee972df54299ff6b96eafaf950 371 SUPERFAMILY SSF47203 214 368 4.51E-30 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS19345 1ce349ee972df54299ff6b96eafaf950 371 SUPERFAMILY SSF56645 11 216 3.14E-45 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS19345 1ce349ee972df54299ff6b96eafaf950 371 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 113 2.9E-12 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS19345 1ce349ee972df54299ff6b96eafaf950 371 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 216 364 2.6E-27 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS02555 e22dd2049766529cf9cebd94b07628e1 98 SUPERFAMILY SSF48600 19 80 5.04E-12 T 28-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CU254_RS02555 e22dd2049766529cf9cebd94b07628e1 98 TIGRFAM TIGR01808 CM_M_hiGC-arch: chorismate mutase 22 94 5.7E-30 T 28-03-2018 IPR010958 Chorismate mutase, high GC Gram-positive bacteria/archaeal CU254_RS02555 e22dd2049766529cf9cebd94b07628e1 98 SMART SM00830 26 86 5.9E-5 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CU254_RS02555 e22dd2049766529cf9cebd94b07628e1 98 Gene3D G3DSA:1.20.59.10 9 96 5.5E-14 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CU254_RS02555 e22dd2049766529cf9cebd94b07628e1 98 Pfam PF01817 Chorismate mutase type II 26 78 3.3E-8 T 28-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CU254_RS35430 73c0cf2998eee1df39181c62977b2075 237 TIGRFAM TIGR00164 PS_decarb_rel: phosphatidylserine decarboxylase homolog 49 232 3.3E-49 T 28-03-2018 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 CU254_RS35430 73c0cf2998eee1df39181c62977b2075 237 Hamap MF_00664 Phosphatidylserine decarboxylase proenzyme [psd]. 23 232 34.601 T 28-03-2018 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 CU254_RS35430 73c0cf2998eee1df39181c62977b2075 237 Pfam PF02666 Phosphatidylserine decarboxylase 61 228 3.9E-28 T 28-03-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 CU254_RS12315 1b5b6c21a915e4326e1a0680d2dcde29 270 Pfam PF00795 Carbon-nitrogen hydrolase 2 244 1.2E-45 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CU254_RS12315 1b5b6c21a915e4326e1a0680d2dcde29 270 Gene3D G3DSA:3.60.110.10 1 260 8.2E-71 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CU254_RS12315 1b5b6c21a915e4326e1a0680d2dcde29 270 SUPERFAMILY SSF56317 1 256 2.09E-70 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CU254_RS12315 1b5b6c21a915e4326e1a0680d2dcde29 270 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 142 162 - T 28-03-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site CU254_RS30260 f6476e0adf026890f212bd412c5b7ef3 422 Gene3D G3DSA:3.90.550.10 14 296 2.6E-38 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS30260 f6476e0adf026890f212bd412c5b7ef3 422 SUPERFAMILY SSF53448 34 311 3.0E-36 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS30260 f6476e0adf026890f212bd412c5b7ef3 422 Pfam PF13641 Glycosyltransferase like family 2 43 274 5.5E-33 T 28-03-2018 CU254_RS04525 7f01d75088638887b06b72342aea01f1 183 SUPERFAMILY SSF48498 81 181 2.97E-5 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS04525 7f01d75088638887b06b72342aea01f1 183 SUPERFAMILY SSF46689 6 79 1.15E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS04525 7f01d75088638887b06b72342aea01f1 183 Gene3D G3DSA:1.10.357.10 2 183 4.8E-32 T 28-03-2018 CU254_RS04525 7f01d75088638887b06b72342aea01f1 183 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 61 1.0E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS40675 75047d79aa405492c955bba45e7a7012 571 SUPERFAMILY SSF90123 12 300 1.83E-28 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CU254_RS40675 75047d79aa405492c955bba45e7a7012 571 Gene3D G3DSA:1.20.1560.10 10 310 5.0E-18 T 28-03-2018 CU254_RS40675 75047d79aa405492c955bba45e7a7012 571 Gene3D G3DSA:3.40.50.300 330 564 3.2E-66 T 28-03-2018 CU254_RS40675 75047d79aa405492c955bba45e7a7012 571 Pfam PF00664 ABC transporter transmembrane region 31 237 8.8E-13 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CU254_RS40675 75047d79aa405492c955bba45e7a7012 571 Pfam PF00005 ABC transporter 350 499 1.3E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS40675 75047d79aa405492c955bba45e7a7012 571 SMART SM00382 359 545 3.1E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS40675 75047d79aa405492c955bba45e7a7012 571 SUPERFAMILY SSF52540 322 565 5.76E-71 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS05710 2ef98c170410c3704d56595ed430104b 224 Gene3D G3DSA:1.10.10.10 122 223 2.7E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS05710 2ef98c170410c3704d56595ed430104b 224 Pfam PF00072 Response regulator receiver domain 3 112 6.9E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS05710 2ef98c170410c3704d56595ed430104b 224 SUPERFAMILY SSF52172 1 170 9.11E-34 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS05710 2ef98c170410c3704d56595ed430104b 224 Gene3D G3DSA:3.40.50.2300 1 121 7.8E-29 T 28-03-2018 CU254_RS05710 2ef98c170410c3704d56595ed430104b 224 SMART SM00448 1 112 4.0E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS05710 2ef98c170410c3704d56595ed430104b 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 217 8.2E-19 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS05710 2ef98c170410c3704d56595ed430104b 224 SMART SM00862 145 217 2.1E-19 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS33300 f2de64f0a9fe8375837638a0c8dd49fc 425 SUPERFAMILY SSF103473 11 424 1.44E-79 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS33300 f2de64f0a9fe8375837638a0c8dd49fc 425 Pfam PF07690 Major Facilitator Superfamily 22 381 3.2E-48 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS33300 f2de64f0a9fe8375837638a0c8dd49fc 425 Gene3D G3DSA:1.20.1250.20 227 425 4.8E-28 T 28-03-2018 CU254_RS33300 f2de64f0a9fe8375837638a0c8dd49fc 425 PIRSF PIRSF002808 1 425 3.2E-35 T 28-03-2018 IPR000849 Sugar phosphate transporter GO:0005215|GO:0006810|GO:0016021 CU254_RS33300 f2de64f0a9fe8375837638a0c8dd49fc 425 Gene3D G3DSA:1.20.1250.20 7 210 1.7E-29 T 28-03-2018 CU254_RS09880 9a529b0ed65c7b041b80506d24b33ed1 279 ProSitePatterns PS00380 Rhodanese signature 1. 37 48 - T 28-03-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 CU254_RS09880 9a529b0ed65c7b041b80506d24b33ed1 279 SMART SM00450 150 270 8.6E-13 T 28-03-2018 IPR001763 Rhodanese-like domain CU254_RS09880 9a529b0ed65c7b041b80506d24b33ed1 279 SMART SM00450 5 129 2.6E-26 T 28-03-2018 IPR001763 Rhodanese-like domain CU254_RS09880 9a529b0ed65c7b041b80506d24b33ed1 279 Gene3D G3DSA:3.40.250.10 146 279 3.7E-23 T 28-03-2018 IPR001763 Rhodanese-like domain CU254_RS09880 9a529b0ed65c7b041b80506d24b33ed1 279 Gene3D G3DSA:3.40.250.10 1 145 1.0E-36 T 28-03-2018 IPR001763 Rhodanese-like domain CU254_RS09880 9a529b0ed65c7b041b80506d24b33ed1 279 Pfam PF00581 Rhodanese-like domain 158 266 3.5E-11 T 28-03-2018 IPR001763 Rhodanese-like domain CU254_RS09880 9a529b0ed65c7b041b80506d24b33ed1 279 Pfam PF00581 Rhodanese-like domain 7 125 6.2E-19 T 28-03-2018 IPR001763 Rhodanese-like domain CU254_RS09880 9a529b0ed65c7b041b80506d24b33ed1 279 SUPERFAMILY SSF52821 3 146 3.01E-39 T 28-03-2018 IPR001763 Rhodanese-like domain CU254_RS09880 9a529b0ed65c7b041b80506d24b33ed1 279 SUPERFAMILY SSF52821 148 277 5.24E-32 T 28-03-2018 IPR001763 Rhodanese-like domain CU254_RS08645 df3ca615a39033bed730dabf1d48d1a5 314 Gene3D G3DSA:3.40.710.10 16 304 0.0015 T 28-03-2018 CU254_RS08645 df3ca615a39033bed730dabf1d48d1a5 314 Pfam PF06089 L-asparaginase II 14 305 9.4E-108 T 28-03-2018 IPR010349 L-asparaginase II CU254_RS12420 4942374a4204d30c3e32cc7b2acd691c 321 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 3 314 4.0E-73 T 28-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CU254_RS12420 4942374a4204d30c3e32cc7b2acd691c 321 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 25 295 1.8E-81 T 28-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CU254_RS12420 4942374a4204d30c3e32cc7b2acd691c 321 SMART SM00797 24 312 2.1E-129 T 28-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CU254_RS12420 4942374a4204d30c3e32cc7b2acd691c 321 SUPERFAMILY SSF50891 176 302 3.15E-9 T 28-03-2018 IPR029000 Cyclophilin-like domain CU254_RS13000 8c51089db0817834f66f16378a7e3f63 426 Gene3D G3DSA:3.50.50.60 5 200 5.2E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS13000 8c51089db0817834f66f16378a7e3f63 426 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 7 336 3.7E-109 T 28-03-2018 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase CU254_RS13000 8c51089db0817834f66f16378a7e3f63 426 Gene3D G3DSA:3.50.50.60 201 421 1.1E-16 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS13000 8c51089db0817834f66f16378a7e3f63 426 SUPERFAMILY SSF51905 266 410 5.18E-13 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS13000 8c51089db0817834f66f16378a7e3f63 426 SUPERFAMILY SSF51905 148 217 5.18E-13 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS13000 8c51089db0817834f66f16378a7e3f63 426 SUPERFAMILY SSF51905 4 225 2.65E-23 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS13000 8c51089db0817834f66f16378a7e3f63 426 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 149 167 1.0E-5 T 28-03-2018 CU254_RS13000 8c51089db0817834f66f16378a7e3f63 426 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 190 208 1.0E-5 T 28-03-2018 CU254_RS13000 8c51089db0817834f66f16378a7e3f63 426 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 1.0E-5 T 28-03-2018 CU254_RS23855 50f830208ee2fbf2dd860cde0bbd2871 528 Gene3D G3DSA:3.40.720.10 21 527 5.0E-37 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CU254_RS23855 50f830208ee2fbf2dd860cde0bbd2871 528 SUPERFAMILY SSF53649 11 97 1.44E-31 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CU254_RS23855 50f830208ee2fbf2dd860cde0bbd2871 528 SUPERFAMILY SSF53649 298 504 1.44E-31 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CU254_RS23855 50f830208ee2fbf2dd860cde0bbd2871 528 SUPERFAMILY SSF53649 167 263 1.44E-31 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CU254_RS23855 50f830208ee2fbf2dd860cde0bbd2871 528 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 23 461 4.6E-26 T 28-03-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 CU254_RS17490 0b3aef1a2450199e5bee57c4fd4d48c3 115 Pfam PF08818 Domain of unknown function (DU1801) 16 108 2.3E-7 T 28-03-2018 IPR014922 Domain of unknown function DUF1801 CU254_RS17490 0b3aef1a2450199e5bee57c4fd4d48c3 115 SUPERFAMILY SSF159888 1 112 5.49E-26 T 28-03-2018 CU254_RS07045 a9b69d0595400fa6dd92df5d7c503b50 210 TIGRFAM TIGR03552 F420_cofC: 2-phospho-L-lactate guanylyltransferase 5 198 1.1E-42 T 28-03-2018 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 CU254_RS07045 a9b69d0595400fa6dd92df5d7c503b50 210 Pfam PF01983 Guanylyl transferase CofC like 5 157 2.0E-6 T 28-03-2018 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 CU254_RS07045 a9b69d0595400fa6dd92df5d7c503b50 210 Hamap MF_02114 2-phospho-L-lactate guanylyltransferase [cofC]. 3 205 20.676 T 28-03-2018 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 CU254_RS07045 a9b69d0595400fa6dd92df5d7c503b50 210 Gene3D G3DSA:3.90.550.10 3 169 7.8E-20 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS07045 a9b69d0595400fa6dd92df5d7c503b50 210 SUPERFAMILY SSF53448 12 198 5.63E-30 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS35890 053c64daee0126ba3304408979aada52 187 Gene3D G3DSA:1.10.260.40 1 67 2.0E-19 T 28-03-2018 CU254_RS35890 053c64daee0126ba3304408979aada52 187 SMART SM00530 14 69 3.8E-17 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS35890 053c64daee0126ba3304408979aada52 187 Gene3D G3DSA:2.60.120.10 68 184 1.8E-17 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS35890 053c64daee0126ba3304408979aada52 187 Pfam PF01381 Helix-turn-helix 15 69 4.6E-15 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS35890 053c64daee0126ba3304408979aada52 187 Pfam PF07883 Cupin domain 107 174 6.3E-12 T 28-03-2018 IPR013096 Cupin 2, conserved barrel CU254_RS35890 053c64daee0126ba3304408979aada52 187 SUPERFAMILY SSF47413 5 74 2.11E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS35890 053c64daee0126ba3304408979aada52 187 SUPERFAMILY SSF51182 66 173 1.32E-19 T 28-03-2018 IPR011051 RmlC-like cupin domain CU254_RS38225 5e11f3c8b54b81274a7d989ec8639e9d 812 Pfam PF02687 FtsX-like permease family 714 801 1.1E-9 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CU254_RS38225 5e11f3c8b54b81274a7d989ec8639e9d 812 Pfam PF02687 FtsX-like permease family 263 359 4.4E-10 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CU254_RS05015 f0489d00e06e5b58c4c30cdfd54ec928 266 Gene3D G3DSA:3.40.30.10 85 262 1.0E-39 T 28-03-2018 CU254_RS05015 f0489d00e06e5b58c4c30cdfd54ec928 266 Pfam PF13462 Thioredoxin 88 255 4.5E-23 T 28-03-2018 IPR012336 Thioredoxin-like fold CU254_RS05015 f0489d00e06e5b58c4c30cdfd54ec928 266 SUPERFAMILY SSF52833 84 255 5.85E-29 T 28-03-2018 IPR012336 Thioredoxin-like fold CU254_RS27575 e2fcbc0caee70c14ca9cca6f81f5e7ce 140 Pfam PF03061 Thioesterase superfamily 17 100 4.8E-9 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CU254_RS27575 e2fcbc0caee70c14ca9cca6f81f5e7ce 140 SUPERFAMILY SSF54637 3 135 6.87E-23 T 28-03-2018 IPR029069 HotDog domain CU254_RS27575 e2fcbc0caee70c14ca9cca6f81f5e7ce 140 Gene3D G3DSA:3.10.129.10 1 140 5.0E-26 T 28-03-2018 CU254_RS07620 2011e649f01bb0134101c41316257271 404 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 236 403 1.7E-49 T 28-03-2018 IPR000160 GGDEF domain CU254_RS07620 2011e649f01bb0134101c41316257271 404 SMART SM00267 229 404 2.3E-48 T 28-03-2018 IPR000160 GGDEF domain CU254_RS07620 2011e649f01bb0134101c41316257271 404 Pfam PF00990 Diguanylate cyclase, GGDEF domain 242 401 1.1E-42 T 28-03-2018 IPR000160 GGDEF domain CU254_RS07620 2011e649f01bb0134101c41316257271 404 Gene3D G3DSA:3.30.70.270 233 404 7.2E-54 T 28-03-2018 CU254_RS07620 2011e649f01bb0134101c41316257271 404 SUPERFAMILY SSF55073 246 403 7.85E-45 T 28-03-2018 IPR029787 Nucleotide cyclase CU254_RS14715 70c20a1c8bc7039aca11b724604891d0 301 SUPERFAMILY SSF56563 7 292 4.84E-26 T 28-03-2018 CU254_RS14715 70c20a1c8bc7039aca11b724604891d0 301 Gene3D G3DSA:3.30.2400.10 27 170 8.1E-12 T 28-03-2018 CU254_RS14715 70c20a1c8bc7039aca11b724604891d0 301 Pfam PF05065 Phage capsid family 10 291 6.8E-16 T 28-03-2018 IPR024455 Phage capsid CU254_RS14715 70c20a1c8bc7039aca11b724604891d0 301 TIGRFAM TIGR01554 major_cap_HK97: phage major capsid protein, HK97 family 12 258 3.4E-19 T 28-03-2018 IPR024455 Phage capsid CU254_RS02615 a069032442cd8c47ff3cd8022e639a4e 520 SUPERFAMILY SSF52335 10 199 2.75E-64 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CU254_RS02615 a069032442cd8c47ff3cd8022e639a4e 520 PIRSF PIRSF000414 4 520 1.2E-197 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CU254_RS02615 a069032442cd8c47ff3cd8022e639a4e 520 SMART SM00851 22 136 2.7E-48 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CU254_RS02615 a069032442cd8c47ff3cd8022e639a4e 520 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 11 520 6.4E-175 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CU254_RS02615 a069032442cd8c47ff3cd8022e639a4e 520 Gene3D G3DSA:3.40.140.20 231 366 4.5E-52 T 28-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CU254_RS02615 a069032442cd8c47ff3cd8022e639a4e 520 SUPERFAMILY SSF53927 219 520 1.5E-118 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CU254_RS02615 a069032442cd8c47ff3cd8022e639a4e 520 Gene3D G3DSA:3.40.50.1380 1 198 5.8E-69 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CU254_RS02615 a069032442cd8c47ff3cd8022e639a4e 520 Pfam PF01808 AICARFT/IMPCHase bienzyme 141 454 9.2E-115 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CU254_RS02615 a069032442cd8c47ff3cd8022e639a4e 520 SMART SM00798 141 455 3.8E-186 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CU254_RS02615 a069032442cd8c47ff3cd8022e639a4e 520 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 10 520 42.427 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CU254_RS02615 a069032442cd8c47ff3cd8022e639a4e 520 Pfam PF02142 MGS-like domain 22 135 7.0E-25 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CU254_RS02615 a069032442cd8c47ff3cd8022e639a4e 520 Gene3D G3DSA:3.40.140.20 367 510 1.8E-49 T 28-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CU254_RS30245 9e01c0d6181f1f10c0f5f902a6b88bf8 366 Pfam PF00676 Dehydrogenase E1 component 47 320 5.4E-76 T 28-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 CU254_RS30245 9e01c0d6181f1f10c0f5f902a6b88bf8 366 Gene3D G3DSA:3.40.50.970 14 357 1.8E-86 T 28-03-2018 CU254_RS30245 9e01c0d6181f1f10c0f5f902a6b88bf8 366 SUPERFAMILY SSF52518 37 358 2.95E-95 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS30245 9e01c0d6181f1f10c0f5f902a6b88bf8 366 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 22 356 6.5E-131 T 28-03-2018 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 CU254_RS32070 906300ac774aebf0fcf02dbf29e1076b 431 Gene3D G3DSA:2.40.110.10 191 281 1.1E-15 T 28-03-2018 CU254_RS32070 906300ac774aebf0fcf02dbf29e1076b 431 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 297 428 1.8E-26 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS32070 906300ac774aebf0fcf02dbf29e1076b 431 Gene3D G3DSA:1.10.540.10 51 188 2.4E-22 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS32070 906300ac774aebf0fcf02dbf29e1076b 431 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 399 418 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CU254_RS32070 906300ac774aebf0fcf02dbf29e1076b 431 SUPERFAMILY SSF47203 299 428 1.77E-34 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS32070 906300ac774aebf0fcf02dbf29e1076b 431 Gene3D G3DSA:1.20.140.10 282 429 2.5E-33 T 28-03-2018 CU254_RS32070 906300ac774aebf0fcf02dbf29e1076b 431 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 75 183 5.4E-21 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS32070 906300ac774aebf0fcf02dbf29e1076b 431 SUPERFAMILY SSF56645 69 292 3.01E-38 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS32070 906300ac774aebf0fcf02dbf29e1076b 431 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 203 282 4.1E-9 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CU254_RS21080 cc8fd1a679acf04c95d44580598d6130 918 SUPERFAMILY SSF51445 358 691 4.75E-67 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS21080 cc8fd1a679acf04c95d44580598d6130 918 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 97 182 1.5E-7 T 28-03-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CU254_RS21080 cc8fd1a679acf04c95d44580598d6130 918 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 382 520 1.6E-6 T 28-03-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 CU254_RS21080 cc8fd1a679acf04c95d44580598d6130 918 Gene3D G3DSA:2.60.40.10 799 892 3.4E-15 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS21080 cc8fd1a679acf04c95d44580598d6130 918 Pfam PF00703 Glycosyl hydrolases family 2 251 361 2.5E-15 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 CU254_RS21080 cc8fd1a679acf04c95d44580598d6130 918 Gene3D G3DSA:2.60.120.260 44 250 2.8E-26 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS21080 cc8fd1a679acf04c95d44580598d6130 918 SUPERFAMILY SSF49303 778 890 1.94E-20 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 CU254_RS21080 cc8fd1a679acf04c95d44580598d6130 918 Gene3D G3DSA:3.20.20.80 380 692 3.2E-48 T 28-03-2018 CU254_RS21080 cc8fd1a679acf04c95d44580598d6130 918 Gene3D G3DSA:2.60.40.10 694 791 1.9E-5 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS21080 cc8fd1a679acf04c95d44580598d6130 918 SUPERFAMILY SSF49303 694 789 8.63E-10 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 CU254_RS21080 cc8fd1a679acf04c95d44580598d6130 918 SUPERFAMILY SSF49303 250 361 5.76E-22 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 CU254_RS21080 cc8fd1a679acf04c95d44580598d6130 918 SUPERFAMILY SSF49785 216 246 1.01E-30 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS21080 cc8fd1a679acf04c95d44580598d6130 918 SUPERFAMILY SSF49785 46 185 1.01E-30 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS21080 cc8fd1a679acf04c95d44580598d6130 918 Gene3D G3DSA:2.60.40.10 251 361 8.7E-19 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS38590 c00766b02b2d57837e2022064e0d8884 644 SMART SM00382 423 608 6.5E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS38590 c00766b02b2d57837e2022064e0d8884 644 Pfam PF00664 ABC transporter transmembrane region 74 347 3.1E-8 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CU254_RS38590 c00766b02b2d57837e2022064e0d8884 644 Gene3D G3DSA:1.20.1560.10 53 385 1.4E-30 T 28-03-2018 CU254_RS38590 c00766b02b2d57837e2022064e0d8884 644 Pfam PF00005 ABC transporter 414 568 1.5E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS38590 c00766b02b2d57837e2022064e0d8884 644 SUPERFAMILY SSF90123 61 360 3.01E-31 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CU254_RS38590 c00766b02b2d57837e2022064e0d8884 644 ProSitePatterns PS00211 ABC transporters family signature. 540 554 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS38590 c00766b02b2d57837e2022064e0d8884 644 SUPERFAMILY SSF52540 389 638 3.73E-79 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS38590 c00766b02b2d57837e2022064e0d8884 644 Gene3D G3DSA:3.40.50.300 394 635 4.4E-71 T 28-03-2018 CU254_RS01065 3832a532772038ddcb72a5e95a39830b 267 Pfam PF01261 Xylose isomerase-like TIM barrel 25 215 8.4E-18 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CU254_RS01065 3832a532772038ddcb72a5e95a39830b 267 Gene3D G3DSA:3.20.20.150 1 267 8.5E-44 T 28-03-2018 CU254_RS01065 3832a532772038ddcb72a5e95a39830b 267 SUPERFAMILY SSF51658 5 257 3.18E-42 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CU254_RS28530 f850a7252d280aaded6494ab5c31b218 1031 Pfam PF14896 EmbC C-terminal domain 680 730 2.6E-9 T 28-03-2018 IPR032731 Arabinosyltransferase, C-terminal CU254_RS28530 f850a7252d280aaded6494ab5c31b218 1031 Pfam PF14896 EmbC C-terminal domain 772 1019 6.6E-48 T 28-03-2018 IPR032731 Arabinosyltransferase, C-terminal CU254_RS28530 f850a7252d280aaded6494ab5c31b218 1031 Gene3D G3DSA:2.60.120.610 21 191 8.4E-39 T 28-03-2018 IPR027451 Arabinofuranosyltransferase, domain 1 CU254_RS28530 f850a7252d280aaded6494ab5c31b218 1031 Pfam PF04602 Mycobacterial cell wall arabinan synthesis protein 2 640 2.5E-226 T 28-03-2018 IPR007680 Arabinofuranosyltransferase, N-terminal GO:0052636|GO:0071766 CU254_RS08970 089c0d9a1f8126ef23e8a5cc30788eb4 727 SMART SM00947 544 709 1.9E-56 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CU254_RS08970 089c0d9a1f8126ef23e8a5cc30788eb4 727 Gene3D G3DSA:3.40.1050.10 516 724 8.1E-63 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CU254_RS08970 089c0d9a1f8126ef23e8a5cc30788eb4 727 Pfam PF00484 Carbonic anhydrase 551 704 1.2E-43 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CU254_RS08970 089c0d9a1f8126ef23e8a5cc30788eb4 727 SUPERFAMILY SSF53056 519 716 2.49E-52 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CU254_RS08970 089c0d9a1f8126ef23e8a5cc30788eb4 727 Pfam PF00916 Sulfate permease family 10 358 4.8E-72 T 28-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 CU254_RS08970 089c0d9a1f8126ef23e8a5cc30788eb4 727 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 598 618 - T 28-03-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CU254_RS36120 d375fb22ef7d42a36c900e37877f09e1 304 SUPERFAMILY SSF53807 39 303 1.18E-51 T 28-03-2018 CU254_RS36120 d375fb22ef7d42a36c900e37877f09e1 304 Gene3D G3DSA:3.40.50.1980 41 177 5.6E-31 T 28-03-2018 CU254_RS36120 d375fb22ef7d42a36c900e37877f09e1 304 Gene3D G3DSA:3.40.50.1980 178 303 1.3E-19 T 28-03-2018 CU254_RS36120 d375fb22ef7d42a36c900e37877f09e1 304 Pfam PF01297 Zinc-uptake complex component A periplasmic 45 299 6.2E-44 T 28-03-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 CU254_RS23225 cf6da7ee198ca378d327544d2d10f5e7 485 Pfam PF00083 Sugar (and other) transporter 320 470 3.5E-6 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CU254_RS23225 cf6da7ee198ca378d327544d2d10f5e7 485 Pfam PF07690 Major Facilitator Superfamily 33 308 3.6E-17 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS23225 cf6da7ee198ca378d327544d2d10f5e7 485 Gene3D G3DSA:1.20.1250.20 268 484 4.5E-27 T 28-03-2018 CU254_RS23225 cf6da7ee198ca378d327544d2d10f5e7 485 Gene3D G3DSA:1.20.1250.20 25 216 3.1E-17 T 28-03-2018 CU254_RS23225 cf6da7ee198ca378d327544d2d10f5e7 485 SUPERFAMILY SSF103473 28 217 2.49E-49 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS23225 cf6da7ee198ca378d327544d2d10f5e7 485 SUPERFAMILY SSF103473 263 478 2.49E-49 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS42260 4497f3e39200652dc9671bfcf258821c 322 Gene3D G3DSA:3.40.50.300 16 258 2.2E-5 T 28-03-2018 CU254_RS24875 4ccd484a774ec24e60672c21bbabdaea 454 Gene3D G3DSA:3.30.830.10 246 444 1.1E-44 T 28-03-2018 CU254_RS24875 4ccd484a774ec24e60672c21bbabdaea 454 SUPERFAMILY SSF63411 28 230 3.0E-55 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CU254_RS24875 4ccd484a774ec24e60672c21bbabdaea 454 Pfam PF05193 Peptidase M16 inactive domain 196 369 8.0E-40 T 28-03-2018 IPR007863 Peptidase M16, C-terminal CU254_RS24875 4ccd484a774ec24e60672c21bbabdaea 454 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 58 81 - T 28-03-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 CU254_RS24875 4ccd484a774ec24e60672c21bbabdaea 454 Gene3D G3DSA:3.30.830.10 9 241 8.3E-59 T 28-03-2018 CU254_RS24875 4ccd484a774ec24e60672c21bbabdaea 454 Pfam PF00675 Insulinase (Peptidase family M16) 37 184 6.4E-39 T 28-03-2018 IPR011765 Peptidase M16, N-terminal CU254_RS24875 4ccd484a774ec24e60672c21bbabdaea 454 SUPERFAMILY SSF63411 254 442 4.15E-48 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CU254_RS17580 fa84f0faf24f6a2eb37c3fb8b899af39 559 Gene3D G3DSA:3.40.50.410 321 548 6.2E-12 T 28-03-2018 IPR002035 von Willebrand factor, type A CU254_RS17580 fa84f0faf24f6a2eb37c3fb8b899af39 559 PIRSF PIRSF031715 1 249 4.1E-25 T 28-03-2018 IPR006538 Cobalt chelatase, CobT subunit GO:0009236 KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 CU254_RS17580 fa84f0faf24f6a2eb37c3fb8b899af39 559 PIRSF PIRSF031715 229 558 1.8E-77 T 28-03-2018 IPR006538 Cobalt chelatase, CobT subunit GO:0009236 KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 CU254_RS17580 fa84f0faf24f6a2eb37c3fb8b899af39 559 SUPERFAMILY SSF53300 432 546 1.73E-9 T 28-03-2018 IPR002035 von Willebrand factor, type A CU254_RS17580 fa84f0faf24f6a2eb37c3fb8b899af39 559 SUPERFAMILY SSF53300 356 397 1.73E-9 T 28-03-2018 IPR002035 von Willebrand factor, type A CU254_RS17580 fa84f0faf24f6a2eb37c3fb8b899af39 559 Pfam PF06213 Cobalamin biosynthesis protein CobT 17 221 1.7E-31 T 28-03-2018 IPR006538 Cobalt chelatase, CobT subunit GO:0009236 KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 CU254_RS17580 fa84f0faf24f6a2eb37c3fb8b899af39 559 Pfam PF11775 Cobalamin biosynthesis protein CobT VWA domain 342 545 1.7E-45 T 28-03-2018 IPR025861 Cobalamin biosynthesis protein CobT VWA domain KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 CU254_RS04255 000ed250f5e991107c730614d36e1a9e 272 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 6 246 1.2E-64 T 28-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CU254_RS04255 000ed250f5e991107c730614d36e1a9e 272 SUPERFAMILY SSF102705 4 267 1.96E-72 T 28-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CU254_RS04255 000ed250f5e991107c730614d36e1a9e 272 Gene3D G3DSA:3.40.1390.30 112 233 2.9E-32 T 28-03-2018 CU254_RS04255 000ed250f5e991107c730614d36e1a9e 272 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 5 235 1.3E-46 T 28-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CU254_RS04255 000ed250f5e991107c730614d36e1a9e 272 Gene3D G3DSA:3.40.1390.30 2 111 1.1E-35 T 28-03-2018 CU254_RS20665 a6a9c0ca82d2343de1615bfad8b06f0c 436 SUPERFAMILY SSF103473 9 431 1.16E-62 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS20665 a6a9c0ca82d2343de1615bfad8b06f0c 436 Pfam PF00083 Sugar (and other) transporter 244 431 6.7E-11 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CU254_RS20665 a6a9c0ca82d2343de1615bfad8b06f0c 436 Pfam PF00083 Sugar (and other) transporter 21 232 6.2E-27 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CU254_RS20665 a6a9c0ca82d2343de1615bfad8b06f0c 436 Gene3D G3DSA:1.20.1250.20 7 226 2.0E-23 T 28-03-2018 CU254_RS20665 a6a9c0ca82d2343de1615bfad8b06f0c 436 Gene3D G3DSA:1.20.1250.20 227 433 5.0E-27 T 28-03-2018 CU254_RS21585 b65be0d64d53321d7ec9c0271b97dd5b 187 Gene3D G3DSA:1.10.260.40 11 75 1.8E-17 T 28-03-2018 CU254_RS21585 b65be0d64d53321d7ec9c0271b97dd5b 187 SUPERFAMILY SSF47413 12 77 5.63E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS21585 b65be0d64d53321d7ec9c0271b97dd5b 187 Pfam PF01381 Helix-turn-helix 17 69 2.4E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS21585 b65be0d64d53321d7ec9c0271b97dd5b 187 SMART SM00530 16 71 1.4E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS21585 b65be0d64d53321d7ec9c0271b97dd5b 187 Gene3D G3DSA:2.60.120.10 76 181 8.3E-10 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS21585 b65be0d64d53321d7ec9c0271b97dd5b 187 SUPERFAMILY SSF51182 64 175 5.67E-16 T 28-03-2018 IPR011051 RmlC-like cupin domain CU254_RS37825 5e76f22d4b5df78121220a6359a144c9 218 Pfam PF01966 HD domain 33 131 1.9E-9 T 28-03-2018 IPR006674 HD domain CU254_RS37825 5e76f22d4b5df78121220a6359a144c9 218 SUPERFAMILY SSF109604 16 161 2.3E-18 T 28-03-2018 CU254_RS37825 5e76f22d4b5df78121220a6359a144c9 218 Gene3D G3DSA:1.10.3210.10 17 182 2.0E-16 T 28-03-2018 CU254_RS23055 c5a35d80e132fb0f91dfa6fd8e957256 497 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 27 439 8.4E-101 T 28-03-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 CU254_RS23055 c5a35d80e132fb0f91dfa6fd8e957256 497 Gene3D G3DSA:3.40.1670.10 329 480 2.0E-32 T 28-03-2018 CU254_RS23055 c5a35d80e132fb0f91dfa6fd8e957256 497 SUPERFAMILY SSF143968 335 488 5.49E-33 T 28-03-2018 CU254_RS23055 c5a35d80e132fb0f91dfa6fd8e957256 497 SUPERFAMILY SSF50475 16 327 3.77E-65 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS11675 c8513b0655401a4289fb0724bef34377 333 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 157 312 7.3E-66 T 28-03-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CU254_RS11675 c8513b0655401a4289fb0724bef34377 333 Gene3D G3DSA:3.30.360.10 162 314 2.7E-65 T 28-03-2018 CU254_RS11675 c8513b0655401a4289fb0724bef34377 333 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 229 246 1.1E-37 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CU254_RS11675 c8513b0655401a4289fb0724bef34377 333 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 110 123 1.1E-37 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CU254_RS11675 c8513b0655401a4289fb0724bef34377 333 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 173 189 1.1E-37 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CU254_RS11675 c8513b0655401a4289fb0724bef34377 333 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 146 164 1.1E-37 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CU254_RS11675 c8513b0655401a4289fb0724bef34377 333 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 269 284 1.1E-37 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CU254_RS11675 c8513b0655401a4289fb0724bef34377 333 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 324 1.0E-131 T 28-03-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CU254_RS11675 c8513b0655401a4289fb0724bef34377 333 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 150 157 - T 28-03-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CU254_RS11675 c8513b0655401a4289fb0724bef34377 333 SUPERFAMILY SSF51735 2 179 3.5E-63 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS11675 c8513b0655401a4289fb0724bef34377 333 SMART SM00846 3 152 5.7E-92 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CU254_RS11675 c8513b0655401a4289fb0724bef34377 333 PIRSF PIRSF000149 1 332 3.8E-130 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CU254_RS11675 c8513b0655401a4289fb0724bef34377 333 SUPERFAMILY SSF55347 152 313 1.45E-68 T 28-03-2018 CU254_RS11675 c8513b0655401a4289fb0724bef34377 333 Gene3D G3DSA:3.40.50.720 1 161 6.1E-77 T 28-03-2018 CU254_RS11675 c8513b0655401a4289fb0724bef34377 333 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 103 9.6E-38 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CU254_RS00525 24488d823b2a11fb8393df9eb9021d31 397 Gene3D G3DSA:1.10.443.10 185 371 1.5E-29 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CU254_RS00525 24488d823b2a11fb8393df9eb9021d31 397 Pfam PF00589 Phage integrase family 211 367 1.5E-17 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CU254_RS00525 24488d823b2a11fb8393df9eb9021d31 397 SUPERFAMILY SSF56349 74 367 3.24E-50 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CU254_RS00525 24488d823b2a11fb8393df9eb9021d31 397 Gene3D G3DSA:1.10.150.130 68 184 2.4E-20 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CU254_RS18960 9137da432b8057aa848978d235032117 114 Gene3D G3DSA:1.10.10.10 2 113 5.2E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS18960 9137da432b8057aa848978d235032117 114 Pfam PF12840 Helix-turn-helix domain 11 70 2.3E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS18960 9137da432b8057aa848978d235032117 114 SUPERFAMILY SSF46785 9 103 2.89E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS18960 9137da432b8057aa848978d235032117 114 SMART SM00418 12 90 5.9E-15 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS18960 9137da432b8057aa848978d235032117 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 14 29 1.3E-5 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS18960 9137da432b8057aa848978d235032117 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 46 61 1.3E-5 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS18960 9137da432b8057aa848978d235032117 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 61 76 1.3E-5 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS00085 b3ba8274b9a65122d17535698298274f 157 Gene3D G3DSA:1.10.10.10 14 154 3.5E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS00085 b3ba8274b9a65122d17535698298274f 157 SMART SM00347 35 133 2.0E-23 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS00085 b3ba8274b9a65122d17535698298274f 157 Pfam PF01047 MarR family 42 100 4.5E-17 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS00085 b3ba8274b9a65122d17535698298274f 157 SUPERFAMILY SSF46785 5 146 6.52E-35 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS00085 b3ba8274b9a65122d17535698298274f 157 PRINTS PR00598 Bacterial regulatory protein MarR family signature 59 75 4.2E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS00085 b3ba8274b9a65122d17535698298274f 157 PRINTS PR00598 Bacterial regulatory protein MarR family signature 76 91 4.2E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS00085 b3ba8274b9a65122d17535698298274f 157 PRINTS PR00598 Bacterial regulatory protein MarR family signature 95 111 4.2E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS02810 fc3e4916e6b53296fbc5f097c8a49a62 138 SUPERFAMILY SSF81343 11 133 7.19E-32 T 28-03-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CU254_RS02810 fc3e4916e6b53296fbc5f097c8a49a62 138 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 9 118 5.7E-15 T 28-03-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CU254_RS02810 fc3e4916e6b53296fbc5f097c8a49a62 138 Gene3D G3DSA:1.20.1300.10 3 132 7.6E-23 T 28-03-2018 CU254_RS04355 8b39a0aa81a35262c78fa27d4a9fe214 451 Gene3D G3DSA:3.90.1150.10 331 451 3.0E-29 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS04355 8b39a0aa81a35262c78fa27d4a9fe214 451 Gene3D G3DSA:3.90.1150.10 15 190 2.0E-38 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS04355 8b39a0aa81a35262c78fa27d4a9fe214 451 TIGRFAM TIGR00700 GABAtrnsam: 4-aminobutyrate transaminase 34 445 3.8E-178 T 28-03-2018 IPR004632 4-aminobutyrate aminotransferase, bacterial GO:0003867|GO:0009448 CU254_RS04355 8b39a0aa81a35262c78fa27d4a9fe214 451 SUPERFAMILY SSF53383 44 445 3.26E-127 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS04355 8b39a0aa81a35262c78fa27d4a9fe214 451 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 261 298 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CU254_RS04355 8b39a0aa81a35262c78fa27d4a9fe214 451 PIRSF PIRSF000521 146 447 7.9E-31 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CU254_RS04355 8b39a0aa81a35262c78fa27d4a9fe214 451 PIRSF PIRSF000521 1 154 2.7E-10 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CU254_RS04355 8b39a0aa81a35262c78fa27d4a9fe214 451 Pfam PF00202 Aminotransferase class-III 47 444 1.7E-124 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CU254_RS04355 8b39a0aa81a35262c78fa27d4a9fe214 451 Gene3D G3DSA:3.40.640.10 204 330 8.5E-42 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS22430 9bc1200d3b0787a12ea995c555fa1acd 332 Gene3D G3DSA:3.90.1260.10 62 301 7.9E-52 T 28-03-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CU254_RS22430 9bc1200d3b0787a12ea995c555fa1acd 332 Pfam PF00764 Arginosuccinate synthase 6 116 3.3E-26 T 28-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CU254_RS22430 9bc1200d3b0787a12ea995c555fa1acd 332 Pfam PF00764 Arginosuccinate synthase 150 299 3.9E-42 T 28-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CU254_RS22430 9bc1200d3b0787a12ea995c555fa1acd 332 SUPERFAMILY SSF52402 4 118 6.28E-18 T 28-03-2018 CU254_RS22430 9bc1200d3b0787a12ea995c555fa1acd 332 SUPERFAMILY SSF69864 150 300 5.23E-42 T 28-03-2018 CU254_RS05135 f9c1d250670621bf85be5205dc2c81aa 402 PRINTS PR00385 P450 superfamily signature 239 256 4.8E-7 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS05135 f9c1d250670621bf85be5205dc2c81aa 402 PRINTS PR00385 P450 superfamily signature 275 286 4.8E-7 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS05135 f9c1d250670621bf85be5205dc2c81aa 402 PRINTS PR00385 P450 superfamily signature 342 351 4.8E-7 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS05135 f9c1d250670621bf85be5205dc2c81aa 402 PRINTS PR00385 P450 superfamily signature 351 362 4.8E-7 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS05135 f9c1d250670621bf85be5205dc2c81aa 402 Pfam PF00067 Cytochrome P450 209 368 7.8E-21 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS05135 f9c1d250670621bf85be5205dc2c81aa 402 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 344 353 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CU254_RS05135 f9c1d250670621bf85be5205dc2c81aa 402 Gene3D G3DSA:1.10.630.10 14 402 1.3E-71 T 28-03-2018 CU254_RS05135 f9c1d250670621bf85be5205dc2c81aa 402 PRINTS PR00359 B-class P450 signature 193 215 3.6E-58 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS05135 f9c1d250670621bf85be5205dc2c81aa 402 PRINTS PR00359 B-class P450 signature 351 362 3.6E-58 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS05135 f9c1d250670621bf85be5205dc2c81aa 402 PRINTS PR00359 B-class P450 signature 275 286 3.6E-58 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS05135 f9c1d250670621bf85be5205dc2c81aa 402 PRINTS PR00359 B-class P450 signature 321 336 3.6E-58 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS05135 f9c1d250670621bf85be5205dc2c81aa 402 PRINTS PR00359 B-class P450 signature 156 171 3.6E-58 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS05135 f9c1d250670621bf85be5205dc2c81aa 402 PRINTS PR00359 B-class P450 signature 139 155 3.6E-58 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS05135 f9c1d250670621bf85be5205dc2c81aa 402 PRINTS PR00359 B-class P450 signature 342 351 3.6E-58 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS05135 f9c1d250670621bf85be5205dc2c81aa 402 PRINTS PR00359 B-class P450 signature 92 103 3.6E-58 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS05135 f9c1d250670621bf85be5205dc2c81aa 402 PRINTS PR00359 B-class P450 signature 293 320 3.6E-58 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS05135 f9c1d250670621bf85be5205dc2c81aa 402 SUPERFAMILY SSF48264 15 402 9.56E-93 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS29085 f405f8155e4e22c7db0c68798a049d34 336 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS29085 f405f8155e4e22c7db0c68798a049d34 336 SUPERFAMILY SSF52540 38 323 2.11E-74 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS29085 f405f8155e4e22c7db0c68798a049d34 336 SMART SM00382 39 228 2.7E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS29085 f405f8155e4e22c7db0c68798a049d34 336 Pfam PF00005 ABC transporter 31 178 1.6E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS29085 f405f8155e4e22c7db0c68798a049d34 336 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 228 316 1.9E-27 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CU254_RS29085 f405f8155e4e22c7db0c68798a049d34 336 Gene3D G3DSA:3.40.50.300 1 328 2.6E-81 T 28-03-2018 CU254_RS29085 f405f8155e4e22c7db0c68798a049d34 336 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 230 297 8.3E-19 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CU254_RS20385 66320a2800c5c8f0272f2c1ec77d7781 251 Pfam PF09339 IclR helix-turn-helix domain 14 63 4.9E-15 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS20385 66320a2800c5c8f0272f2c1ec77d7781 251 Gene3D G3DSA:3.30.450.40 77 250 6.3E-47 T 28-03-2018 IPR029016 GAF domain-like CU254_RS20385 66320a2800c5c8f0272f2c1ec77d7781 251 SUPERFAMILY SSF55781 73 247 7.19E-45 T 28-03-2018 IPR029016 GAF domain-like CU254_RS20385 66320a2800c5c8f0272f2c1ec77d7781 251 SMART SM00346 14 98 6.5E-19 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS20385 66320a2800c5c8f0272f2c1ec77d7781 251 SUPERFAMILY SSF46785 14 82 3.52E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS20385 66320a2800c5c8f0272f2c1ec77d7781 251 Pfam PF01614 Bacterial transcriptional regulator 129 246 1.5E-28 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal CU254_RS20385 66320a2800c5c8f0272f2c1ec77d7781 251 Gene3D G3DSA:1.10.10.10 4 76 3.0E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS00705 6c20ab79631ef17134c69cf7431bae13 359 Gene3D G3DSA:3.30.1870.10 42 118 8.4E-21 T 28-03-2018 CU254_RS00705 6c20ab79631ef17134c69cf7431bae13 359 Gene3D G3DSA:1.20.1440.30 127 249 2.7E-6 T 28-03-2018 CU254_RS00705 6c20ab79631ef17134c69cf7431bae13 359 SUPERFAMILY SSF159501 12 359 3.92E-75 T 28-03-2018 CU254_RS00705 6c20ab79631ef17134c69cf7431bae13 359 Gene3D G3DSA:3.40.1660.10 250 359 1.6E-6 T 28-03-2018 CU254_RS00705 6c20ab79631ef17134c69cf7431bae13 359 Pfam PF05139 Erythromycin esterase 40 358 3.7E-56 T 28-03-2018 IPR007815 Erythromycin esterase GO:0046677 CU254_RS11925 e591d8e6b1fb272dc99a89ee9227e5cf 241 Gene3D G3DSA:3.40.50.1820 15 228 1.1E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS11925 e591d8e6b1fb272dc99a89ee9227e5cf 241 SUPERFAMILY SSF53474 21 212 2.7E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS11925 e591d8e6b1fb272dc99a89ee9227e5cf 241 Pfam PF12697 Alpha/beta hydrolase family 32 231 7.1E-11 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS34760 ec3ba0678f371691cf4b2acd61e14b3e 237 Pfam PF08241 Methyltransferase domain 49 142 1.5E-21 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CU254_RS34760 ec3ba0678f371691cf4b2acd61e14b3e 237 SUPERFAMILY SSF53335 25 203 8.67E-38 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS34760 ec3ba0678f371691cf4b2acd61e14b3e 237 Gene3D G3DSA:3.40.50.150 26 230 1.3E-33 T 28-03-2018 CU254_RS19945 1496765ce5133bd28b3db48621274287 287 TIGRFAM TIGR02271 TIGR02271: conserved domain 172 279 1.0E-15 T 28-03-2018 IPR019060 Domain of unknown function DUF2382 CU254_RS19945 1496765ce5133bd28b3db48621274287 287 SUPERFAMILY SSF50346 4 108 6.67E-19 T 28-03-2018 IPR011033 PRC-barrel-like CU254_RS19945 1496765ce5133bd28b3db48621274287 287 Pfam PF05239 PRC-barrel domain 8 75 4.4E-8 T 28-03-2018 IPR027275 PRC-barrel domain CU254_RS19945 1496765ce5133bd28b3db48621274287 287 Gene3D G3DSA:3.90.50.10 2 123 1.3E-23 T 28-03-2018 CU254_RS19945 1496765ce5133bd28b3db48621274287 287 Pfam PF09557 Domain of unknown function (DUF2382) 170 277 2.3E-32 T 28-03-2018 IPR019060 Domain of unknown function DUF2382 CU254_RS36395 75c813794b42891fda7932eb9799b23e 419 PIRSF PIRSF000412 2 412 2.8E-162 T 28-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CU254_RS36395 75c813794b42891fda7932eb9799b23e 419 Pfam PF00464 Serine hydroxymethyltransferase 11 386 8.0E-156 T 28-03-2018 CU254_RS36395 75c813794b42891fda7932eb9799b23e 419 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 224 240 - T 28-03-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CU254_RS36395 75c813794b42891fda7932eb9799b23e 419 Gene3D G3DSA:3.90.1150.10 275 415 1.6E-57 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS36395 75c813794b42891fda7932eb9799b23e 419 Gene3D G3DSA:3.40.640.10 39 274 6.9E-53 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS36395 75c813794b42891fda7932eb9799b23e 419 SUPERFAMILY SSF53383 8 417 1.24E-165 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS36395 75c813794b42891fda7932eb9799b23e 419 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 9 416 49.496 T 28-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CU254_RS06520 a1d3fcfeecace21b46d2a7705bed20be 253 SUPERFAMILY SSF56784 87 250 4.62E-8 T 28-03-2018 IPR023214 HAD-like domain CU254_RS06520 a1d3fcfeecace21b46d2a7705bed20be 253 Gene3D G3DSA:3.40.50.1000 62 239 2.8E-8 T 28-03-2018 IPR023214 HAD-like domain CU254_RS06520 a1d3fcfeecace21b46d2a7705bed20be 253 Pfam PF03767 HAD superfamily, subfamily IIIB (Acid phosphatase) 69 252 3.0E-28 T 28-03-2018 IPR005519 Acid phosphatase, class B-like CU254_RS31900 0017c3aad77d2abb5339bd7199e19824 423 PIRSF PIRSF000521 5 141 0.0069 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CU254_RS31900 0017c3aad77d2abb5339bd7199e19824 423 PIRSF PIRSF000521 169 420 1.4E-12 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CU254_RS31900 0017c3aad77d2abb5339bd7199e19824 423 Gene3D G3DSA:3.90.1150.10 308 423 9.0E-17 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS31900 0017c3aad77d2abb5339bd7199e19824 423 Pfam PF00202 Aminotransferase class-III 24 415 1.6E-78 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CU254_RS31900 0017c3aad77d2abb5339bd7199e19824 423 Gene3D G3DSA:3.40.640.10 178 307 1.0E-35 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS31900 0017c3aad77d2abb5339bd7199e19824 423 Gene3D G3DSA:3.90.1150.10 1 177 4.6E-38 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS31900 0017c3aad77d2abb5339bd7199e19824 423 SUPERFAMILY SSF53383 8 419 5.25E-101 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS00910 e1caac16e0c8127f452377e3e213effd 465 Gene3D G3DSA:1.20.200.10 214 454 2.2E-44 T 28-03-2018 CU254_RS00910 e1caac16e0c8127f452377e3e213effd 465 Gene3D G3DSA:1.10.275.10 2 178 3.6E-44 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal CU254_RS00910 e1caac16e0c8127f452377e3e213effd 465 Pfam PF00221 Aromatic amino acid lyase 6 423 6.8E-82 T 28-03-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 CU254_RS00910 e1caac16e0c8127f452377e3e213effd 465 SUPERFAMILY SSF48557 6 450 5.49E-88 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 CU254_RS25425 b71bb4239fd24eb93675433f2f5dff11 413 Gene3D G3DSA:1.10.3470.10 50 226 2.5E-10 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CU254_RS25425 b71bb4239fd24eb93675433f2f5dff11 413 Gene3D G3DSA:1.10.3470.10 235 403 1.7E-13 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CU254_RS25425 b71bb4239fd24eb93675433f2f5dff11 413 Pfam PF02653 Branched-chain amino acid transport system / permease component 57 398 2.4E-40 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CU254_RS10645 86991e7ce2c98b2317c4159096bcaab8 355 Pfam PF00005 ABC transporter 22 162 3.3E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS10645 86991e7ce2c98b2317c4159096bcaab8 355 SMART SM00382 29 221 1.9E-21 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS10645 86991e7ce2c98b2317c4159096bcaab8 355 SUPERFAMILY SSF50331 240 345 1.33E-10 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CU254_RS10645 86991e7ce2c98b2317c4159096bcaab8 355 Gene3D G3DSA:2.40.50.100 242 300 4.6E-5 T 28-03-2018 CU254_RS10645 86991e7ce2c98b2317c4159096bcaab8 355 SUPERFAMILY SSF52540 5 245 4.51E-81 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS10645 86991e7ce2c98b2317c4159096bcaab8 355 Gene3D G3DSA:3.40.50.300 1 241 1.6E-73 T 28-03-2018 CU254_RS10645 86991e7ce2c98b2317c4159096bcaab8 355 Pfam PF08402 TOBE domain 279 345 2.8E-5 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CU254_RS10645 86991e7ce2c98b2317c4159096bcaab8 355 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS23095 5e2f57fd1ff7f75011537e341ff39df1 727 Gene3D G3DSA:1.20.1640.10 465 689 1.2E-33 T 28-03-2018 CU254_RS23095 5e2f57fd1ff7f75011537e341ff39df1 727 Gene3D G3DSA:1.20.1640.10 124 333 8.6E-34 T 28-03-2018 CU254_RS23095 5e2f57fd1ff7f75011537e341ff39df1 727 SUPERFAMILY SSF82866 140 332 1.44E-30 T 28-03-2018 CU254_RS23095 5e2f57fd1ff7f75011537e341ff39df1 727 Pfam PF03176 MMPL family 430 691 3.2E-38 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CU254_RS23095 5e2f57fd1ff7f75011537e341ff39df1 727 Pfam PF03176 MMPL family 48 360 5.5E-69 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CU254_RS23095 5e2f57fd1ff7f75011537e341ff39df1 727 SUPERFAMILY SSF82866 458 691 2.09E-30 T 28-03-2018 CU254_RS02535 b17c7bf4ee95489b55abacf03a662fcc 547 Gene3D G3DSA:1.10.510.10 100 536 1.9E-48 T 28-03-2018 CU254_RS02535 b17c7bf4ee95489b55abacf03a662fcc 547 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 136 148 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CU254_RS02535 b17c7bf4ee95489b55abacf03a662fcc 547 SUPERFAMILY SSF56112 4 269 6.79E-71 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS02535 b17c7bf4ee95489b55abacf03a662fcc 547 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 18 41 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 CU254_RS02535 b17c7bf4ee95489b55abacf03a662fcc 547 SMART SM00220 12 271 2.2E-62 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CU254_RS02535 b17c7bf4ee95489b55abacf03a662fcc 547 Gene3D G3DSA:3.30.200.20 1 99 3.2E-22 T 28-03-2018 CU254_RS02535 b17c7bf4ee95489b55abacf03a662fcc 547 Pfam PF00069 Protein kinase domain 12 264 3.3E-47 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CU254_RS29935 cdd539229ec1493f902e9e60ba1ba717 255 Gene3D G3DSA:3.40.1410.10 78 249 4.4E-33 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CU254_RS29935 cdd539229ec1493f902e9e60ba1ba717 255 SMART SM00345 8 67 3.4E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS29935 cdd539229ec1493f902e9e60ba1ba717 255 SUPERFAMILY SSF46785 5 80 5.84E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS29935 cdd539229ec1493f902e9e60ba1ba717 255 SMART SM00866 109 246 1.9E-13 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CU254_RS29935 cdd539229ec1493f902e9e60ba1ba717 255 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 57 1.1E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS29935 cdd539229ec1493f902e9e60ba1ba717 255 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 27 41 1.1E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS29935 cdd539229ec1493f902e9e60ba1ba717 255 SUPERFAMILY SSF64288 55 252 2.51E-26 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CU254_RS29935 cdd539229ec1493f902e9e60ba1ba717 255 Pfam PF07702 UTRA domain 114 245 4.6E-20 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CU254_RS29935 cdd539229ec1493f902e9e60ba1ba717 255 Pfam PF00392 Bacterial regulatory proteins, gntR family 5 67 2.3E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS29935 cdd539229ec1493f902e9e60ba1ba717 255 Gene3D G3DSA:1.10.10.10 4 69 5.7E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS29445 b79cb92850c38e13d00302178bf601bf 284 Gene3D G3DSA:3.40.630.30 18 163 1.1E-7 T 28-03-2018 CU254_RS29445 b79cb92850c38e13d00302178bf601bf 284 SUPERFAMILY SSF55729 24 137 6.76E-8 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS08350 b83263d543891c507fb1cfd074e6d678 111 Gene3D G3DSA:2.60.120.10 4 110 1.3E-17 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS08350 b83263d543891c507fb1cfd074e6d678 111 Pfam PF12973 ChrR Cupin-like domain 25 106 3.6E-18 T 28-03-2018 IPR025979 ChrR-like cupin domain CU254_RS08350 b83263d543891c507fb1cfd074e6d678 111 SUPERFAMILY SSF51182 13 107 3.43E-19 T 28-03-2018 IPR011051 RmlC-like cupin domain CU254_RS05820 36809e6501754f28d6406a7e5f6a9c94 407 PRINTS PR00359 B-class P450 signature 300 327 3.4E-41 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS05820 36809e6501754f28d6406a7e5f6a9c94 407 PRINTS PR00359 B-class P450 signature 94 105 3.4E-41 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS05820 36809e6501754f28d6406a7e5f6a9c94 407 PRINTS PR00359 B-class P450 signature 283 294 3.4E-41 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS05820 36809e6501754f28d6406a7e5f6a9c94 407 PRINTS PR00359 B-class P450 signature 141 157 3.4E-41 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS05820 36809e6501754f28d6406a7e5f6a9c94 407 PRINTS PR00359 B-class P450 signature 349 358 3.4E-41 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS05820 36809e6501754f28d6406a7e5f6a9c94 407 PRINTS PR00359 B-class P450 signature 158 173 3.4E-41 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS05820 36809e6501754f28d6406a7e5f6a9c94 407 PRINTS PR00359 B-class P450 signature 328 343 3.4E-41 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS05820 36809e6501754f28d6406a7e5f6a9c94 407 PRINTS PR00359 B-class P450 signature 358 369 3.4E-41 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS05820 36809e6501754f28d6406a7e5f6a9c94 407 PRINTS PR00359 B-class P450 signature 201 223 3.4E-41 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS05820 36809e6501754f28d6406a7e5f6a9c94 407 Gene3D G3DSA:1.10.630.10 13 406 9.0E-72 T 28-03-2018 CU254_RS05820 36809e6501754f28d6406a7e5f6a9c94 407 PRINTS PR00385 P450 superfamily signature 283 294 4.1E-5 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS05820 36809e6501754f28d6406a7e5f6a9c94 407 PRINTS PR00385 P450 superfamily signature 349 358 4.1E-5 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS05820 36809e6501754f28d6406a7e5f6a9c94 407 PRINTS PR00385 P450 superfamily signature 358 369 4.1E-5 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS05820 36809e6501754f28d6406a7e5f6a9c94 407 PRINTS PR00385 P450 superfamily signature 247 264 4.1E-5 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS05820 36809e6501754f28d6406a7e5f6a9c94 407 SUPERFAMILY SSF48264 21 406 7.99E-82 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS05820 36809e6501754f28d6406a7e5f6a9c94 407 Pfam PF00067 Cytochrome P450 283 380 4.0E-18 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS05820 36809e6501754f28d6406a7e5f6a9c94 407 Pfam PF00067 Cytochrome P450 190 275 2.6E-8 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS39965 5539dfa56eac6ba814dd7f6e7da7e3fc 271 Pfam PF02585 GlcNAc-PI de-N-acetylase 6 147 2.0E-24 T 28-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 CU254_RS39965 5539dfa56eac6ba814dd7f6e7da7e3fc 271 SUPERFAMILY SSF102588 2 270 2.09E-63 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CU254_RS39965 5539dfa56eac6ba814dd7f6e7da7e3fc 271 TIGRFAM TIGR03446 mycothiol_Mca: mycothiol conjugate amidase Mca 3 270 7.3E-98 T 28-03-2018 IPR017811 Mycothiol S-conjugate amidase Mca GO:0010126 KEGG: 00311+3.5.1.11 CU254_RS39965 5539dfa56eac6ba814dd7f6e7da7e3fc 271 Hamap MF_01482 Mycothiol S-conjugate amidase [mca]. 6 271 41.916 T 28-03-2018 IPR017811 Mycothiol S-conjugate amidase Mca GO:0010126 KEGG: 00311+3.5.1.11 CU254_RS39965 5539dfa56eac6ba814dd7f6e7da7e3fc 271 Gene3D G3DSA:3.40.50.10320 1 271 2.0E-64 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CU254_RS27000 8b69961f8dbebea60601752374c49c81 274 Pfam PF02634 FdhD/NarQ family 26 272 4.8E-80 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CU254_RS27000 8b69961f8dbebea60601752374c49c81 274 Hamap MF_00187 Sulfurtransferase FdhD [fdhD]. 2 273 33.675 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CU254_RS27000 8b69961f8dbebea60601752374c49c81 274 Gene3D G3DSA:3.10.20.10 28 120 3.9E-31 T 28-03-2018 CU254_RS27000 8b69961f8dbebea60601752374c49c81 274 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 22 273 2.0E-52 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CU254_RS27000 8b69961f8dbebea60601752374c49c81 274 SUPERFAMILY SSF53927 4 272 1.93E-77 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CU254_RS27000 8b69961f8dbebea60601752374c49c81 274 PIRSF PIRSF015626 2 274 5.8E-86 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CU254_RS27000 8b69961f8dbebea60601752374c49c81 274 Gene3D G3DSA:3.40.140.10 136 274 2.2E-55 T 28-03-2018 CU254_RS14885 152db02a20920481fc517e2f7f95f66e 532 Pfam PF00239 Resolvase, N terminal domain 55 198 8.9E-15 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CU254_RS14885 152db02a20920481fc517e2f7f95f66e 532 SUPERFAMILY SSF53041 54 197 2.09E-12 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CU254_RS14885 152db02a20920481fc517e2f7f95f66e 532 SMART SM00857 54 199 6.0E-9 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CU254_RS14885 152db02a20920481fc517e2f7f95f66e 532 Pfam PF07508 Recombinase 218 304 1.1E-6 T 28-03-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 CU254_RS14885 152db02a20920481fc517e2f7f95f66e 532 Gene3D G3DSA:3.40.50.1390 49 205 3.2E-18 T 28-03-2018 CU254_RS03215 c6aa37a512a315e171d4c826bbd9fce8 597 Gene3D G3DSA:3.30.470.20 221 459 3.7E-93 T 28-03-2018 CU254_RS03215 c6aa37a512a315e171d4c826bbd9fce8 597 Pfam PF02785 Biotin carboxylase C-terminal domain 346 456 2.3E-35 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CU254_RS03215 c6aa37a512a315e171d4c826bbd9fce8 597 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 126 334 7.0E-80 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CU254_RS03215 c6aa37a512a315e171d4c826bbd9fce8 597 Gene3D G3DSA:2.40.50.100 527 597 9.1E-20 T 28-03-2018 CU254_RS03215 c6aa37a512a315e171d4c826bbd9fce8 597 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 297 304 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CU254_RS03215 c6aa37a512a315e171d4c826bbd9fce8 597 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 552 569 - T 28-03-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CU254_RS03215 c6aa37a512a315e171d4c826bbd9fce8 597 SMART SM00878 346 456 6.0E-55 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CU254_RS03215 c6aa37a512a315e171d4c826bbd9fce8 597 SUPERFAMILY SSF51246 340 460 3.98E-36 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CU254_RS03215 c6aa37a512a315e171d4c826bbd9fce8 597 SUPERFAMILY SSF56059 126 335 7.42E-62 T 28-03-2018 CU254_RS03215 c6aa37a512a315e171d4c826bbd9fce8 597 Pfam PF00364 Biotin-requiring enzyme 530 595 1.8E-17 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CU254_RS03215 c6aa37a512a315e171d4c826bbd9fce8 597 SUPERFAMILY SSF52440 11 124 3.53E-47 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CU254_RS03215 c6aa37a512a315e171d4c826bbd9fce8 597 Gene3D G3DSA:3.30.1490.20 135 220 1.6E-18 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CU254_RS03215 c6aa37a512a315e171d4c826bbd9fce8 597 Gene3D G3DSA:3.40.50.20 13 134 5.3E-49 T 28-03-2018 CU254_RS03215 c6aa37a512a315e171d4c826bbd9fce8 597 SUPERFAMILY SSF51230 526 595 2.36E-20 T 28-03-2018 IPR011053 Single hybrid motif CU254_RS03215 c6aa37a512a315e171d4c826bbd9fce8 597 Pfam PF00289 Biotin carboxylase, N-terminal domain 13 121 7.9E-44 T 28-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CU254_RS25490 02580e57a62eeea42f14566088a7cd53 250 Pfam PF01966 HD domain 60 149 3.6E-6 T 28-03-2018 IPR006674 HD domain CU254_RS25490 02580e57a62eeea42f14566088a7cd53 250 SUPERFAMILY SSF109604 58 152 4.4E-14 T 28-03-2018 CU254_RS25490 02580e57a62eeea42f14566088a7cd53 250 Gene3D G3DSA:1.10.3210.10 40 170 9.7E-12 T 28-03-2018 CU254_RS22485 ebf097f6aa48c6e57d269cefa236b83c 351 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 58 343 8.7E-88 T 28-03-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CU254_RS22485 ebf097f6aa48c6e57d269cefa236b83c 351 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 21 347 44.329 T 28-03-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 CU254_RS22485 ebf097f6aa48c6e57d269cefa236b83c 351 SUPERFAMILY SSF55681 105 344 3.42E-76 T 28-03-2018 CU254_RS22485 ebf097f6aa48c6e57d269cefa236b83c 351 Gene3D G3DSA:3.30.930.10 20 350 5.4E-80 T 28-03-2018 CU254_RS22485 ebf097f6aa48c6e57d269cefa236b83c 351 Pfam PF01409 tRNA synthetases class II core domain (F) 105 344 3.3E-98 T 28-03-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 CU254_RS22485 ebf097f6aa48c6e57d269cefa236b83c 351 SUPERFAMILY SSF46589 27 111 4.97E-14 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 CU254_RS22485 ebf097f6aa48c6e57d269cefa236b83c 351 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 33 100 1.6E-17 T 28-03-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CU254_RS41440 4d163f546aebdf243d01cba6d6370fa8 357 Gene3D G3DSA:3.90.120.10 179 340 4.6E-22 T 28-03-2018 CU254_RS41440 4d163f546aebdf243d01cba6d6370fa8 357 SUPERFAMILY SSF53335 8 350 2.15E-68 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS41440 4d163f546aebdf243d01cba6d6370fa8 357 ProSitePatterns PS00094 C-5 cytosine-specific DNA methylases active site. 79 91 - T 28-03-2018 IPR018117 DNA methylase, C-5 cytosine-specific, active site KEGG: 00270+2.1.1.37|Reactome: R-HSA-212300|Reactome: R-HSA-5334118 CU254_RS41440 4d163f546aebdf243d01cba6d6370fa8 357 Pfam PF00145 C-5 cytosine-specific DNA methylase 8 190 1.7E-40 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS41440 4d163f546aebdf243d01cba6d6370fa8 357 Pfam PF00145 C-5 cytosine-specific DNA methylase 301 349 3.7E-10 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS41440 4d163f546aebdf243d01cba6d6370fa8 357 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 8 188 1.4E-36 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CU254_RS41440 4d163f546aebdf243d01cba6d6370fa8 357 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 170 183 4.6E-13 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CU254_RS41440 4d163f546aebdf243d01cba6d6370fa8 357 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 122 136 4.6E-13 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CU254_RS41440 4d163f546aebdf243d01cba6d6370fa8 357 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 6 22 4.6E-13 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CU254_RS41440 4d163f546aebdf243d01cba6d6370fa8 357 Gene3D G3DSA:3.40.50.150 6 178 2.0E-44 T 28-03-2018 CU254_RS14895 76df4a32a8b7cf837b3ca485635ec7ad 187 Pfam PF07336 Putative stress-induced transcription regulator 14 135 1.8E-19 T 28-03-2018 IPR010852 Putative stress-induced transcription regulator CU254_RS14895 76df4a32a8b7cf837b3ca485635ec7ad 187 SUPERFAMILY SSF160904 7 181 2.75E-41 T 28-03-2018 CU254_RS14895 76df4a32a8b7cf837b3ca485635ec7ad 187 Gene3D G3DSA:1.10.3300.10 6 185 6.6E-40 T 28-03-2018 IPR023286 ABATE domain CU254_RS14895 76df4a32a8b7cf837b3ca485635ec7ad 187 Pfam PF11706 CGNR zinc finger 141 182 1.0E-15 T 28-03-2018 IPR021005 Zinc finger, CGNR CU254_RS03100 8b247f726845bad54848821de2d166e1 261 Pfam PF01048 Phosphorylase superfamily 22 259 5.7E-41 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CU254_RS03100 8b247f726845bad54848821de2d166e1 261 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 22 258 3.3E-77 T 28-03-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 CU254_RS03100 8b247f726845bad54848821de2d166e1 261 PIRSF PIRSF000477 1 261 2.7E-92 T 28-03-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 CU254_RS03100 8b247f726845bad54848821de2d166e1 261 SUPERFAMILY SSF53167 6 259 2.64E-79 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CU254_RS03100 8b247f726845bad54848821de2d166e1 261 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 76 117 - T 28-03-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 CU254_RS03100 8b247f726845bad54848821de2d166e1 261 Gene3D G3DSA:3.40.50.1580 1 261 5.1E-58 T 28-03-2018 CU254_RS03100 8b247f726845bad54848821de2d166e1 261 TIGRFAM TIGR01698 PUNP: purine nucleotide phosphorylase 22 258 2.5E-98 T 28-03-2018 IPR011269 Putative purine nucleotide phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 CU254_RS15430 0d422f80f2506e5a5a9c14150e7fbed2 266 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 156 184 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS15430 0d422f80f2506e5a5a9c14150e7fbed2 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 157 2.7E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS15430 0d422f80f2506e5a5a9c14150e7fbed2 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 97 108 2.7E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS15430 0d422f80f2506e5a5a9c14150e7fbed2 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 169 188 2.7E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS15430 0d422f80f2506e5a5a9c14150e7fbed2 266 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 30 260 2.2E-53 T 28-03-2018 CU254_RS15430 0d422f80f2506e5a5a9c14150e7fbed2 266 SUPERFAMILY SSF51735 20 263 7.43E-75 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS15430 0d422f80f2506e5a5a9c14150e7fbed2 266 Gene3D G3DSA:3.40.50.720 1 264 7.3E-72 T 28-03-2018 CU254_RS15430 0d422f80f2506e5a5a9c14150e7fbed2 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 22 39 1.9E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS15430 0d422f80f2506e5a5a9c14150e7fbed2 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 188 1.9E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS15430 0d422f80f2506e5a5a9c14150e7fbed2 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 224 244 1.9E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS15430 0d422f80f2506e5a5a9c14150e7fbed2 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 97 108 1.9E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS15430 0d422f80f2506e5a5a9c14150e7fbed2 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 159 1.9E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS15430 0d422f80f2506e5a5a9c14150e7fbed2 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 190 207 1.9E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18360 46e3da317c0f6dbc1823ca9857f66174 475 ProSitePatterns PS00571 Amidases signature. 143 174 - T 28-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CU254_RS18360 46e3da317c0f6dbc1823ca9857f66174 475 SUPERFAMILY SSF75304 5 470 2.75E-119 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS18360 46e3da317c0f6dbc1823ca9857f66174 475 Pfam PF01425 Amidase 54 451 9.4E-90 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS18360 46e3da317c0f6dbc1823ca9857f66174 475 Gene3D G3DSA:3.90.1300.10 2 475 1.0E-122 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS39545 36e10a86a847a981cda18a0904304b5e 670 SUPERFAMILY SSF52540 62 244 5.48E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS39545 36e10a86a847a981cda18a0904304b5e 670 Gene3D G3DSA:3.40.50.300 31 193 2.8E-8 T 28-03-2018 CU254_RS39545 36e10a86a847a981cda18a0904304b5e 670 Pfam PF00931 NB-ARC domain 65 243 8.0E-6 T 28-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 CU254_RS39545 36e10a86a847a981cda18a0904304b5e 670 Gene3D G3DSA:1.25.40.10 452 670 7.1E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS14560 79daf12924a1df3af134c0726763dea7 453 PRINTS PR01036 Tetracycline resistance protein TetB signature 138 162 2.1E-5 T 28-03-2018 CU254_RS14560 79daf12924a1df3af134c0726763dea7 453 PRINTS PR01036 Tetracycline resistance protein TetB signature 16 40 2.1E-5 T 28-03-2018 CU254_RS14560 79daf12924a1df3af134c0726763dea7 453 PRINTS PR01036 Tetracycline resistance protein TetB signature 76 98 2.1E-5 T 28-03-2018 CU254_RS14560 79daf12924a1df3af134c0726763dea7 453 Gene3D G3DSA:1.20.1250.20 248 452 8.6E-28 T 28-03-2018 CU254_RS14560 79daf12924a1df3af134c0726763dea7 453 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 13 415 1.1E-69 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CU254_RS14560 79daf12924a1df3af134c0726763dea7 453 Gene3D G3DSA:1.20.1250.20 1 200 6.9E-35 T 28-03-2018 CU254_RS14560 79daf12924a1df3af134c0726763dea7 453 Pfam PF07690 Major Facilitator Superfamily 21 401 1.7E-49 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS14560 79daf12924a1df3af134c0726763dea7 453 SUPERFAMILY SSF103473 6 200 2.49E-67 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS14560 79daf12924a1df3af134c0726763dea7 453 SUPERFAMILY SSF103473 244 442 2.49E-67 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS25690 ad6b5644422213b744cd76f4464e0aee 303 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 141 162 - T 28-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 CU254_RS25690 ad6b5644422213b744cd76f4464e0aee 303 SUPERFAMILY SSF51735 114 274 8.98E-30 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS25690 ad6b5644422213b744cd76f4464e0aee 303 Gene3D G3DSA:3.90.180.10 233 303 6.8E-7 T 28-03-2018 CU254_RS25690 ad6b5644422213b744cd76f4464e0aee 303 Gene3D G3DSA:3.40.50.720 151 232 1.7E-15 T 28-03-2018 CU254_RS25690 ad6b5644422213b744cd76f4464e0aee 303 Gene3D G3DSA:3.90.180.10 1 150 1.3E-49 T 28-03-2018 CU254_RS25690 ad6b5644422213b744cd76f4464e0aee 303 SMART SM00829 10 300 2.8E-16 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CU254_RS25690 ad6b5644422213b744cd76f4464e0aee 303 Pfam PF13602 Zinc-binding dehydrogenase 184 300 2.6E-16 T 28-03-2018 CU254_RS25690 ad6b5644422213b744cd76f4464e0aee 303 SUPERFAMILY SSF50129 1 154 5.78E-37 T 28-03-2018 IPR011032 GroES-like CU254_RS25690 ad6b5644422213b744cd76f4464e0aee 303 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 117 1.6E-12 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CU254_RS19615 5a19a266a4e710da1e4d987a6bdbff8a 569 Gene3D G3DSA:2.60.120.260 445 569 2.6E-17 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS19615 5a19a266a4e710da1e4d987a6bdbff8a 569 Pfam PF00704 Glycosyl hydrolases family 18 34 228 7.4E-17 T 28-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 CU254_RS19615 5a19a266a4e710da1e4d987a6bdbff8a 569 SUPERFAMILY SSF49785 447 568 1.31E-9 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS19615 5a19a266a4e710da1e4d987a6bdbff8a 569 SUPERFAMILY SSF51445 13 246 6.91E-21 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS19615 5a19a266a4e710da1e4d987a6bdbff8a 569 SUPERFAMILY SSF51445 276 308 6.91E-21 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS19615 5a19a266a4e710da1e4d987a6bdbff8a 569 Gene3D G3DSA:3.20.20.80 28 316 1.4E-28 T 28-03-2018 CU254_RS19615 5a19a266a4e710da1e4d987a6bdbff8a 569 Pfam PF02018 Carbohydrate binding domain 448 554 6.8E-6 T 28-03-2018 IPR003305 Carbohydrate-binding, CenC-like GO:0016798 CU254_RS19615 5a19a266a4e710da1e4d987a6bdbff8a 569 Gene3D G3DSA:2.60.40.10 353 444 1.9E-5 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS32640 00084568b6170e5884761879b01e2c51 365 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 241 327 5.6E-25 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CU254_RS32640 00084568b6170e5884761879b01e2c51 365 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 243 307 8.3E-19 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CU254_RS32640 00084568b6170e5884761879b01e2c51 365 SUPERFAMILY SSF52540 15 261 2.11E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS32640 00084568b6170e5884761879b01e2c51 365 Pfam PF00005 ABC transporter 35 191 9.0E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS32640 00084568b6170e5884761879b01e2c51 365 Gene3D G3DSA:3.40.50.300 11 340 7.5E-80 T 28-03-2018 CU254_RS32640 00084568b6170e5884761879b01e2c51 365 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS32640 00084568b6170e5884761879b01e2c51 365 SMART SM00382 43 258 1.5E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS06920 e2b8b10e53063d343f45732b437269be 532 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 195 217 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CU254_RS06920 e2b8b10e53063d343f45732b437269be 532 Gene3D G3DSA:3.30.70.260 454 529 6.2E-15 T 28-03-2018 CU254_RS06920 e2b8b10e53063d343f45732b437269be 532 SUPERFAMILY SSF143548 324 453 1.02E-30 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CU254_RS06920 e2b8b10e53063d343f45732b437269be 532 SUPERFAMILY SSF51735 103 284 1.84E-60 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS06920 e2b8b10e53063d343f45732b437269be 532 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 284 6.2E-63 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CU254_RS06920 e2b8b10e53063d343f45732b437269be 532 Gene3D G3DSA:3.30.1330.90 319 453 2.7E-30 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CU254_RS06920 e2b8b10e53063d343f45732b437269be 532 Pfam PF01842 ACT domain 459 517 3.6E-12 T 28-03-2018 IPR002912 ACT domain CU254_RS06920 e2b8b10e53063d343f45732b437269be 532 Gene3D G3DSA:3.40.50.720 116 287 1.5E-60 T 28-03-2018 CU254_RS06920 e2b8b10e53063d343f45732b437269be 532 TIGRFAM TIGR01327 PGDH: phosphoglycerate dehydrogenase 9 530 4.9E-187 T 28-03-2018 IPR006236 D-3-phosphoglycerate dehydrogenase GO:0004617|GO:0006564 KEGG: 00260+1.1.1.95|KEGG: 00680+1.1.1.95|Reactome: R-HSA-977347 CU254_RS06920 e2b8b10e53063d343f45732b437269be 532 SUPERFAMILY SSF52283 6 137 4.91E-37 T 28-03-2018 CU254_RS06920 e2b8b10e53063d343f45732b437269be 532 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 147 174 - T 28-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 CU254_RS06920 e2b8b10e53063d343f45732b437269be 532 SUPERFAMILY SSF55021 457 530 2.69E-14 T 28-03-2018 CU254_RS06920 e2b8b10e53063d343f45732b437269be 532 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 224 240 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CU254_RS06920 e2b8b10e53063d343f45732b437269be 532 Gene3D G3DSA:3.40.50.720 6 115 6.1E-33 T 28-03-2018 CU254_RS06920 e2b8b10e53063d343f45732b437269be 532 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 9 316 7.0E-33 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CU254_RS02255 f1b5c0360530f7ab92e16df19a817e1d 366 SUPERFAMILY SSF50331 238 365 5.35E-27 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CU254_RS02255 f1b5c0360530f7ab92e16df19a817e1d 366 Gene3D G3DSA:3.40.50.300 2 247 9.3E-67 T 28-03-2018 CU254_RS02255 f1b5c0360530f7ab92e16df19a817e1d 366 Pfam PF00005 ABC transporter 22 163 4.5E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS02255 f1b5c0360530f7ab92e16df19a817e1d 366 Gene3D G3DSA:2.40.50.100 248 281 4.3E-10 T 28-03-2018 CU254_RS02255 f1b5c0360530f7ab92e16df19a817e1d 366 SUPERFAMILY SSF52540 5 244 2.73E-82 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS02255 f1b5c0360530f7ab92e16df19a817e1d 366 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS02255 f1b5c0360530f7ab92e16df19a817e1d 366 SMART SM00382 30 213 1.0E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS02255 f1b5c0360530f7ab92e16df19a817e1d 366 Pfam PF08402 TOBE domain 278 357 1.9E-6 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CU254_RS02255 f1b5c0360530f7ab92e16df19a817e1d 366 Gene3D G3DSA:2.40.50.140 282 350 1.2E-16 T 28-03-2018 CU254_RS02245 39bfb39594d3cc0976ef5a4a78e3221d 274 SMART SM00420 21 73 3.6E-10 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CU254_RS02245 39bfb39594d3cc0976ef5a4a78e3221d 274 SUPERFAMILY SSF46785 19 77 1.52E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS02245 39bfb39594d3cc0976ef5a4a78e3221d 274 ProSitePatterns PS00894 DeoR-type HTH domain signature. 21 55 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CU254_RS02245 39bfb39594d3cc0976ef5a4a78e3221d 274 Pfam PF08220 DeoR-like helix-turn-helix domain 21 71 3.3E-11 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CU254_RS02245 39bfb39594d3cc0976ef5a4a78e3221d 274 Gene3D G3DSA:1.10.10.10 14 87 2.6E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS02245 39bfb39594d3cc0976ef5a4a78e3221d 274 SUPERFAMILY SSF100950 88 243 3.45E-23 T 28-03-2018 CU254_RS02245 39bfb39594d3cc0976ef5a4a78e3221d 274 Gene3D G3DSA:3.40.50.1360 88 256 2.6E-32 T 28-03-2018 CU254_RS02245 39bfb39594d3cc0976ef5a4a78e3221d 274 SMART SM01134 86 244 8.5E-51 T 28-03-2018 CU254_RS02245 39bfb39594d3cc0976ef5a4a78e3221d 274 Pfam PF00455 DeoR C terminal sensor domain 88 242 6.8E-40 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain CU254_RS30935 87ebd160ed90889984f662815ba0e89e 581 Pfam PF00672 HAMP domain 309 353 3.7E-12 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS30935 87ebd160ed90889984f662815ba0e89e 581 SMART SM00387 470 581 2.5E-44 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS30935 87ebd160ed90889984f662815ba0e89e 581 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 471 580 2.6E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS30935 87ebd160ed90889984f662815ba0e89e 581 Gene3D G3DSA:3.30.565.10 429 581 6.3E-49 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS30935 87ebd160ed90889984f662815ba0e89e 581 Gene3D G3DSA:1.20.1300.10 4 88 7.0E-5 T 28-03-2018 CU254_RS30935 87ebd160ed90889984f662815ba0e89e 581 SMART SM00304 308 360 4.2E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS30935 87ebd160ed90889984f662815ba0e89e 581 SUPERFAMILY SSF47384 344 425 2.16E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS30935 87ebd160ed90889984f662815ba0e89e 581 SUPERFAMILY SSF55874 414 580 1.7E-49 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS30935 87ebd160ed90889984f662815ba0e89e 581 Gene3D G3DSA:1.10.287.130 351 420 1.9E-14 T 28-03-2018 CU254_RS30935 87ebd160ed90889984f662815ba0e89e 581 SUPERFAMILY SSF158472 309 354 2.88E-9 T 28-03-2018 CU254_RS30935 87ebd160ed90889984f662815ba0e89e 581 PRINTS PR00344 Bacterial sensor protein C-terminal signature 566 579 5.3E-19 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS30935 87ebd160ed90889984f662815ba0e89e 581 PRINTS PR00344 Bacterial sensor protein C-terminal signature 542 560 5.3E-19 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS30935 87ebd160ed90889984f662815ba0e89e 581 PRINTS PR00344 Bacterial sensor protein C-terminal signature 525 535 5.3E-19 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS30935 87ebd160ed90889984f662815ba0e89e 581 PRINTS PR00344 Bacterial sensor protein C-terminal signature 507 521 5.3E-19 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS30935 87ebd160ed90889984f662815ba0e89e 581 Pfam PF00512 His Kinase A (phospho-acceptor) domain 362 425 3.3E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS30935 87ebd160ed90889984f662815ba0e89e 581 SMART SM00388 361 425 6.9E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS34765 58be28bb26bb511efa5dc89f90879a73 478 Gene3D G3DSA:3.30.43.10 2 105 2.9E-18 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CU254_RS34765 58be28bb26bb511efa5dc89f90879a73 478 Pfam PF02913 FAD linked oxidases, C-terminal domain 225 476 5.0E-34 T 28-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CU254_RS34765 58be28bb26bb511efa5dc89f90879a73 478 SUPERFAMILY SSF55103 202 476 6.7E-33 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CU254_RS34765 58be28bb26bb511efa5dc89f90879a73 478 Gene3D G3DSA:3.30.465.10 107 252 3.0E-30 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CU254_RS34765 58be28bb26bb511efa5dc89f90879a73 478 SUPERFAMILY SSF56176 5 225 2.71E-49 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CU254_RS34765 58be28bb26bb511efa5dc89f90879a73 478 Pfam PF01565 FAD binding domain 47 186 1.2E-35 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CU254_RS34765 58be28bb26bb511efa5dc89f90879a73 478 Gene3D G3DSA:1.10.45.10 438 476 1.0E-11 T 28-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CU254_RS23840 f4d4f3052273b305f28625f9a9bbb5f8 324 Pfam PF00107 Zinc-binding dehydrogenase 150 274 1.0E-28 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CU254_RS23840 f4d4f3052273b305f28625f9a9bbb5f8 324 SUPERFAMILY SSF50129 1 137 1.38E-39 T 28-03-2018 IPR011032 GroES-like CU254_RS23840 f4d4f3052273b305f28625f9a9bbb5f8 324 Gene3D G3DSA:3.90.180.10 1 134 2.2E-34 T 28-03-2018 CU254_RS23840 f4d4f3052273b305f28625f9a9bbb5f8 324 Gene3D G3DSA:3.40.50.720 135 256 5.8E-28 T 28-03-2018 CU254_RS23840 f4d4f3052273b305f28625f9a9bbb5f8 324 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 89 1.2E-8 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CU254_RS23840 f4d4f3052273b305f28625f9a9bbb5f8 324 SUPERFAMILY SSF51735 110 270 3.36E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS23840 f4d4f3052273b305f28625f9a9bbb5f8 324 Gene3D G3DSA:3.90.180.10 257 324 0.0032 T 28-03-2018 CU254_RS23840 f4d4f3052273b305f28625f9a9bbb5f8 324 SMART SM00829 11 320 1.3E-43 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CU254_RS23840 f4d4f3052273b305f28625f9a9bbb5f8 324 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 139 160 - T 28-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 CU254_RS31340 4e4492db14f5bdebfc67529c79e16bbb 399 Pfam PF01548 Transposase 3 158 7.0E-29 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CU254_RS31340 4e4492db14f5bdebfc67529c79e16bbb 399 Pfam PF02371 Transposase IS116/IS110/IS902 family 266 350 3.8E-10 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CU254_RS28120 db9ac52fda8e89c80fcd7b8700de66f1 263 SUPERFAMILY SSF140959 12 262 1.57E-79 T 28-03-2018 CU254_RS28120 db9ac52fda8e89c80fcd7b8700de66f1 263 Hamap MF_01972 Tryptophan 2,3-dioxygenase [kynA]. 6 263 36.21 T 28-03-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 CU254_RS28120 db9ac52fda8e89c80fcd7b8700de66f1 263 Pfam PF03301 Tryptophan 2,3-dioxygenase 191 262 1.2E-19 T 28-03-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 CU254_RS28120 db9ac52fda8e89c80fcd7b8700de66f1 263 Pfam PF03301 Tryptophan 2,3-dioxygenase 6 132 1.3E-39 T 28-03-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 CU254_RS20375 40b334094484352a7c729bea3eb1f417 341 Gene3D G3DSA:1.10.8.60 276 337 4.8E-30 T 28-03-2018 CU254_RS20375 40b334094484352a7c729bea3eb1f417 341 Hamap MF_01656 4-hydroxy-2-oxovalerate aldolase [mhpE]. 1 341 166.699 T 28-03-2018 IPR017629 4-hydroxy-2-oxovalerate aldolase GO:0008701|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 CU254_RS20375 40b334094484352a7c729bea3eb1f417 341 TIGRFAM TIGR03217 4OH_2_O_val_ald: 4-hydroxy-2-oxovalerate aldolase 5 336 5.9E-144 T 28-03-2018 IPR017629 4-hydroxy-2-oxovalerate aldolase GO:0008701|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 CU254_RS20375 40b334094484352a7c729bea3eb1f417 341 ProDom PD005364 ALDOLASE 4-HYDROXY-2-OXOVALERATE LYASE PYRUVATE 4.1.3.- PLASMID HMG-COA LYASE-LIKE TRANSFERASE HOA 275 333 3.0E-15 T 28-03-2018 IPR012425 DmpG-like communication GO:0016833|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 CU254_RS20375 40b334094484352a7c729bea3eb1f417 341 Pfam PF00682 HMGL-like 6 263 5.7E-51 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CU254_RS20375 40b334094484352a7c729bea3eb1f417 341 SUPERFAMILY SSF51569 3 269 9.67E-61 T 28-03-2018 CU254_RS20375 40b334094484352a7c729bea3eb1f417 341 Gene3D G3DSA:3.20.20.70 1 268 4.1E-52 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS20375 40b334094484352a7c729bea3eb1f417 341 Pfam PF07836 DmpG-like communication domain 273 334 8.9E-30 T 28-03-2018 IPR012425 DmpG-like communication GO:0016833|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 CU254_RS20375 40b334094484352a7c729bea3eb1f417 341 SUPERFAMILY SSF89000 288 337 2.16E-17 T 28-03-2018 CU254_RS31600 8f960051688a33844774e2686a0dd59a 237 Gene3D G3DSA:3.40.50.300 2 236 2.1E-62 T 28-03-2018 CU254_RS31600 8f960051688a33844774e2686a0dd59a 237 SMART SM00382 30 206 1.1E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS31600 8f960051688a33844774e2686a0dd59a 237 Pfam PF00005 ABC transporter 21 158 1.8E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS31600 8f960051688a33844774e2686a0dd59a 237 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS31600 8f960051688a33844774e2686a0dd59a 237 SUPERFAMILY SSF52540 6 219 4.33E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS28020 250d03fc62629e7842844a66b5db1a3b 633 Pfam PF00082 Subtilase family 247 617 2.0E-17 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS28020 250d03fc62629e7842844a66b5db1a3b 633 SUPERFAMILY SSF52743 525 628 4.58E-29 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS28020 250d03fc62629e7842844a66b5db1a3b 633 SUPERFAMILY SSF52743 178 324 4.58E-29 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS28020 250d03fc62629e7842844a66b5db1a3b 633 SUPERFAMILY SSF52743 465 479 4.58E-29 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS28020 250d03fc62629e7842844a66b5db1a3b 633 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 567 577 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CU254_RS28020 250d03fc62629e7842844a66b5db1a3b 633 PRINTS PR00723 Subtilisin serine protease family (S8) signature 198 217 9.2E-7 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CU254_RS28020 250d03fc62629e7842844a66b5db1a3b 633 PRINTS PR00723 Subtilisin serine protease family (S8) signature 566 582 9.2E-7 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CU254_RS28020 250d03fc62629e7842844a66b5db1a3b 633 Gene3D G3DSA:3.40.50.200 178 632 8.5E-35 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS28175 457dec51f9e9e565ea8c9ddc8fc9cba8 564 SUPERFAMILY SSF56672 156 563 2.45E-58 T 28-03-2018 CU254_RS28175 457dec51f9e9e565ea8c9ddc8fc9cba8 564 SMART SM00482 311 522 2.6E-7 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CU254_RS28175 457dec51f9e9e565ea8c9ddc8fc9cba8 564 PRINTS PR00868 DNA-polymerase family A (pol I) signature 325 348 8.4E-7 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CU254_RS28175 457dec51f9e9e565ea8c9ddc8fc9cba8 564 PRINTS PR00868 DNA-polymerase family A (pol I) signature 505 518 8.4E-7 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CU254_RS28175 457dec51f9e9e565ea8c9ddc8fc9cba8 564 PRINTS PR00868 DNA-polymerase family A (pol I) signature 478 494 8.4E-7 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CU254_RS28175 457dec51f9e9e565ea8c9ddc8fc9cba8 564 Pfam PF00476 DNA polymerase family A 207 545 3.4E-24 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CU254_RS28175 457dec51f9e9e565ea8c9ddc8fc9cba8 564 Gene3D G3DSA:3.30.70.370 288 372 4.9E-10 T 28-03-2018 CU254_RS28175 457dec51f9e9e565ea8c9ddc8fc9cba8 564 Gene3D G3DSA:3.30.70.370 383 564 9.2E-19 T 28-03-2018 CU254_RS39235 b4812142841691c2a12e2e8f1698691e 559 SUPERFAMILY SSF48295 450 555 1.62E-34 T 28-03-2018 IPR010921 Trp repressor/replication initiator GO:0043565 CU254_RS39235 b4812142841691c2a12e2e8f1698691e 559 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 284 298 1.0E-51 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CU254_RS39235 b4812142841691c2a12e2e8f1698691e 559 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 350 377 1.0E-51 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CU254_RS39235 b4812142841691c2a12e2e8f1698691e 559 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 252 272 1.0E-51 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CU254_RS39235 b4812142841691c2a12e2e8f1698691e 559 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 316 330 1.0E-51 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CU254_RS39235 b4812142841691c2a12e2e8f1698691e 559 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 513 532 1.0E-51 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CU254_RS39235 b4812142841691c2a12e2e8f1698691e 559 Gene3D G3DSA:1.10.8.60 385 456 2.7E-25 T 28-03-2018 CU254_RS39235 b4812142841691c2a12e2e8f1698691e 559 Pfam PF00308 Bacterial dnaA protein 219 436 1.4E-102 T 28-03-2018 IPR013317 Chromosomal replication initiator protein DnaA CU254_RS39235 b4812142841691c2a12e2e8f1698691e 559 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 12 553 4.6E-154 T 28-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CU254_RS39235 b4812142841691c2a12e2e8f1698691e 559 SMART SM00760 463 532 1.8E-33 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CU254_RS39235 b4812142841691c2a12e2e8f1698691e 559 Gene3D G3DSA:3.40.50.300 216 383 3.2E-23 T 28-03-2018 CU254_RS39235 b4812142841691c2a12e2e8f1698691e 559 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 466 532 1.5E-27 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CU254_RS39235 b4812142841691c2a12e2e8f1698691e 559 Gene3D G3DSA:1.10.1750.10 460 556 1.6E-34 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CU254_RS39235 b4812142841691c2a12e2e8f1698691e 559 SUPERFAMILY SSF52540 218 430 6.67E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS39235 b4812142841691c2a12e2e8f1698691e 559 SMART SM00382 251 379 4.8E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS39235 b4812142841691c2a12e2e8f1698691e 559 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 9 554 32.823 T 28-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CU254_RS39235 b4812142841691c2a12e2e8f1698691e 559 ProSitePatterns PS01008 DnaA protein signature. 513 532 - T 28-03-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CU254_RS36840 0c4ea4fb5767c25787a92c6d19e45605 716 Pfam PF00905 Penicillin binding protein transpeptidase domain 361 639 9.7E-11 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CU254_RS36840 0c4ea4fb5767c25787a92c6d19e45605 716 Gene3D G3DSA:1.10.3810.10 59 271 1.6E-72 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CU254_RS36840 0c4ea4fb5767c25787a92c6d19e45605 716 SUPERFAMILY SSF53955 54 275 5.06E-67 T 28-03-2018 IPR023346 Lysozyme-like domain CU254_RS36840 0c4ea4fb5767c25787a92c6d19e45605 716 SUPERFAMILY SSF56601 293 505 5.63E-58 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CU254_RS36840 0c4ea4fb5767c25787a92c6d19e45605 716 SUPERFAMILY SSF56601 538 712 5.63E-58 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CU254_RS36840 0c4ea4fb5767c25787a92c6d19e45605 716 SUPERFAMILY SSF56601 234 256 5.63E-58 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CU254_RS36840 0c4ea4fb5767c25787a92c6d19e45605 716 Pfam PF00912 Transglycosylase 66 252 2.3E-59 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CU254_RS36840 0c4ea4fb5767c25787a92c6d19e45605 716 Gene3D G3DSA:3.40.710.10 288 716 1.4E-58 T 28-03-2018 CU254_RS34030 d32c62d276f9f2ad95c3b421e487fa2d 390 Gene3D G3DSA:1.20.1250.20 4 208 6.2E-26 T 28-03-2018 CU254_RS34030 d32c62d276f9f2ad95c3b421e487fa2d 390 Gene3D G3DSA:1.20.1250.20 209 390 2.2E-17 T 28-03-2018 CU254_RS34030 d32c62d276f9f2ad95c3b421e487fa2d 390 SUPERFAMILY SSF103473 13 389 1.57E-53 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS34030 d32c62d276f9f2ad95c3b421e487fa2d 390 PRINTS PR01035 Tetracycline resistance protein signature 55 74 3.3E-6 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CU254_RS34030 d32c62d276f9f2ad95c3b421e487fa2d 390 PRINTS PR01035 Tetracycline resistance protein signature 144 166 3.3E-6 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CU254_RS34030 d32c62d276f9f2ad95c3b421e487fa2d 390 PRINTS PR01035 Tetracycline resistance protein signature 237 254 3.3E-6 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CU254_RS34030 d32c62d276f9f2ad95c3b421e487fa2d 390 PRINTS PR01035 Tetracycline resistance protein signature 26 42 3.3E-6 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CU254_RS34030 d32c62d276f9f2ad95c3b421e487fa2d 390 Pfam PF07690 Major Facilitator Superfamily 23 354 1.2E-35 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS28215 64658877bbc3804193da7212488a5860 217 SMART SM00345 15 73 7.0E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS28215 64658877bbc3804193da7212488a5860 217 SUPERFAMILY SSF48008 82 213 4.45E-26 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS28215 64658877bbc3804193da7212488a5860 217 Gene3D G3DSA:1.20.120.530 70 217 2.0E-33 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS28215 64658877bbc3804193da7212488a5860 217 Pfam PF07729 FCD domain 84 204 6.3E-25 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS28215 64658877bbc3804193da7212488a5860 217 Gene3D G3DSA:1.10.10.10 4 69 3.0E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS28215 64658877bbc3804193da7212488a5860 217 SUPERFAMILY SSF46785 9 99 1.18E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS28215 64658877bbc3804193da7212488a5860 217 SMART SM00895 83 205 2.6E-19 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS28215 64658877bbc3804193da7212488a5860 217 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 73 5.6E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS39620 8ce0b3114fdba88c19bddd5d8d786c8b 244 SUPERFAMILY SSF52540 11 234 1.25E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS39620 8ce0b3114fdba88c19bddd5d8d786c8b 244 Pfam PF00005 ABC transporter 15 163 2.0E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS39620 8ce0b3114fdba88c19bddd5d8d786c8b 244 Gene3D G3DSA:3.40.50.300 2 243 9.9E-63 T 28-03-2018 CU254_RS39620 8ce0b3114fdba88c19bddd5d8d786c8b 244 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS39620 8ce0b3114fdba88c19bddd5d8d786c8b 244 SMART SM00382 23 212 1.2E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS33455 96973e53be42187c337a6fee62fc5162 582 SUPERFAMILY SSF51905 466 527 2.71E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS33455 96973e53be42187c337a6fee62fc5162 582 SUPERFAMILY SSF51905 5 307 2.71E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS33455 96973e53be42187c337a6fee62fc5162 582 Pfam PF00732 GMC oxidoreductase 192 281 1.7E-4 T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CU254_RS33455 96973e53be42187c337a6fee62fc5162 582 Pfam PF13450 NAD(P)-binding Rossmann-like domain 12 41 5.4E-5 T 28-03-2018 CU254_RS33455 96973e53be42187c337a6fee62fc5162 582 Pfam PF05199 GMC oxidoreductase 464 521 3.0E-15 T 28-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 CU254_RS33455 96973e53be42187c337a6fee62fc5162 582 Gene3D G3DSA:3.50.50.60 1 539 8.4E-60 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS07990 4cd45c833f5ba3eed65b1be16114d362 122 ProSitePatterns PS01015 Ribosomal protein L19 signature. 85 100 - T 28-03-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS07990 4cd45c833f5ba3eed65b1be16114d362 122 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 1 113 30.051 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS07990 4cd45c833f5ba3eed65b1be16114d362 122 Pfam PF01245 Ribosomal protein L19 4 112 7.6E-50 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS07990 4cd45c833f5ba3eed65b1be16114d362 122 PRINTS PR00061 Ribosomal protein L19 signature 3 32 1.2E-41 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS07990 4cd45c833f5ba3eed65b1be16114d362 122 PRINTS PR00061 Ribosomal protein L19 signature 33 62 1.2E-41 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS07990 4cd45c833f5ba3eed65b1be16114d362 122 PRINTS PR00061 Ribosomal protein L19 signature 87 112 1.2E-41 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS07990 4cd45c833f5ba3eed65b1be16114d362 122 PIRSF PIRSF002191 1 122 7.1E-51 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS07990 4cd45c833f5ba3eed65b1be16114d362 122 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 2 112 4.7E-49 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS07990 4cd45c833f5ba3eed65b1be16114d362 122 SUPERFAMILY SSF50104 1 115 6.42E-47 T 28-03-2018 IPR008991 Translation protein SH3-like domain CU254_RS28380 d329ae7af8da0d72a96619c34365a53b 308 Gene3D G3DSA:3.30.200.20 35 102 3.3E-7 T 28-03-2018 CU254_RS28380 d329ae7af8da0d72a96619c34365a53b 308 SUPERFAMILY SSF56112 45 275 3.7E-27 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS28380 d329ae7af8da0d72a96619c34365a53b 308 Gene3D G3DSA:3.90.1200.10 103 281 6.7E-10 T 28-03-2018 CU254_RS28380 d329ae7af8da0d72a96619c34365a53b 308 PIRSF PIRSF000707 4 308 5.7E-82 T 28-03-2018 IPR016259 Hygromycin-B kinase KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 CU254_RS28380 d329ae7af8da0d72a96619c34365a53b 308 Pfam PF01636 Phosphotransferase enzyme family 39 257 1.3E-26 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CU254_RS21965 06258579c8d43ff2e02b5607fec15dfc 733 Gene3D G3DSA:2.60.40.10 10 109 1.7E-13 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS21965 06258579c8d43ff2e02b5607fec15dfc 733 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 127 213 9.0E-23 T 28-03-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077 CU254_RS21965 06258579c8d43ff2e02b5607fec15dfc 733 Pfam PF00128 Alpha amylase, catalytic domain 277 344 5.4E-8 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CU254_RS21965 06258579c8d43ff2e02b5607fec15dfc 733 Gene3D G3DSA:2.60.40.10 114 229 1.1E-32 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS21965 06258579c8d43ff2e02b5607fec15dfc 733 SUPERFAMILY SSF81296 22 116 1.08E-16 T 28-03-2018 IPR014756 Immunoglobulin E-set CU254_RS21965 06258579c8d43ff2e02b5607fec15dfc 733 SUPERFAMILY SSF51011 624 725 4.92E-34 T 28-03-2018 CU254_RS21965 06258579c8d43ff2e02b5607fec15dfc 733 SMART SM00642 256 605 9.9E-8 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CU254_RS21965 06258579c8d43ff2e02b5607fec15dfc 733 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 629 724 1.1E-21 T 28-03-2018 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 CU254_RS21965 06258579c8d43ff2e02b5607fec15dfc 733 PIRSF PIRSF000463 14 733 2.2E-293 T 28-03-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077 CU254_RS21965 06258579c8d43ff2e02b5607fec15dfc 733 SUPERFAMILY SSF51445 186 620 3.93E-116 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS21965 06258579c8d43ff2e02b5607fec15dfc 733 Gene3D G3DSA:3.20.20.80 240 634 9.6E-77 T 28-03-2018 CU254_RS21965 06258579c8d43ff2e02b5607fec15dfc 733 Gene3D G3DSA:2.60.40.1180 635 727 4.2E-36 T 28-03-2018 CU254_RS21965 06258579c8d43ff2e02b5607fec15dfc 733 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 111 724 1.0E-285 T 28-03-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077 CU254_RS21965 06258579c8d43ff2e02b5607fec15dfc 733 SUPERFAMILY SSF81296 145 207 3.08E-10 T 28-03-2018 IPR014756 Immunoglobulin E-set CU254_RS21965 06258579c8d43ff2e02b5607fec15dfc 733 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 103 727 45.133 T 28-03-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|Reactome: R-HSA-3322077 CU254_RS33230 dcce1da55165470c8e087790aa894548 265 Pfam PF04454 Encapsulating protein for peroxidase 1 251 1.5E-80 T 28-03-2018 IPR007544 Encapsulating protein for peroxidase GO:0008233|GO:0042742 CU254_RS33230 dcce1da55165470c8e087790aa894548 265 PIRSF PIRSF019254 1 265 4.7E-79 T 28-03-2018 IPR007544 Encapsulating protein for peroxidase GO:0008233|GO:0042742 CU254_RS18675 185061a22452de67c52bfb06501de62c 274 Pfam PF12697 Alpha/beta hydrolase family 24 265 8.2E-23 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS18675 185061a22452de67c52bfb06501de62c 274 SUPERFAMILY SSF53474 2 271 7.37E-66 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS18675 185061a22452de67c52bfb06501de62c 274 Gene3D G3DSA:3.40.50.1820 1 273 4.5E-56 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS18675 185061a22452de67c52bfb06501de62c 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 50 65 5.7E-22 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS18675 185061a22452de67c52bfb06501de62c 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 217 231 5.7E-22 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS18675 185061a22452de67c52bfb06501de62c 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 92 105 5.7E-22 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS18675 185061a22452de67c52bfb06501de62c 274 PRINTS PR00111 Alpha/beta hydrolase fold signature 106 119 5.7E-22 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS18675 185061a22452de67c52bfb06501de62c 274 PRINTS PR00412 Epoxide hydrolase signature 50 65 1.7E-12 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS18675 185061a22452de67c52bfb06501de62c 274 PRINTS PR00412 Epoxide hydrolase signature 106 119 1.7E-12 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS18675 185061a22452de67c52bfb06501de62c 274 PRINTS PR00412 Epoxide hydrolase signature 215 231 1.7E-12 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS18675 185061a22452de67c52bfb06501de62c 274 PRINTS PR00412 Epoxide hydrolase signature 248 270 1.7E-12 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS01940 b85f9b135c1ad45af38d8d1dd1fed4a5 397 SUPERFAMILY SSF52540 6 221 2.39E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS01940 b85f9b135c1ad45af38d8d1dd1fed4a5 397 SUPERFAMILY SSF50447 207 304 2.08E-30 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CU254_RS01940 b85f9b135c1ad45af38d8d1dd1fed4a5 397 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 5.4E-58 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CU254_RS01940 b85f9b135c1ad45af38d8d1dd1fed4a5 397 PRINTS PR00315 GTP-binding elongation factor signature 80 90 2.7E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CU254_RS01940 b85f9b135c1ad45af38d8d1dd1fed4a5 397 PRINTS PR00315 GTP-binding elongation factor signature 133 142 2.7E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CU254_RS01940 b85f9b135c1ad45af38d8d1dd1fed4a5 397 PRINTS PR00315 GTP-binding elongation factor signature 14 27 2.7E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CU254_RS01940 b85f9b135c1ad45af38d8d1dd1fed4a5 397 PRINTS PR00315 GTP-binding elongation factor signature 96 107 2.7E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CU254_RS01940 b85f9b135c1ad45af38d8d1dd1fed4a5 397 PRINTS PR00315 GTP-binding elongation factor signature 60 68 2.7E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CU254_RS01940 b85f9b135c1ad45af38d8d1dd1fed4a5 397 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 2 397 1.5E-219 T 28-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CU254_RS01940 b85f9b135c1ad45af38d8d1dd1fed4a5 397 Pfam PF03144 Elongation factor Tu domain 2 227 296 8.3E-16 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CU254_RS01940 b85f9b135c1ad45af38d8d1dd1fed4a5 397 SUPERFAMILY SSF50465 305 397 2.62E-35 T 28-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal CU254_RS01940 b85f9b135c1ad45af38d8d1dd1fed4a5 397 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 147 1.4E-13 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CU254_RS01940 b85f9b135c1ad45af38d8d1dd1fed4a5 397 Gene3D G3DSA:2.40.30.10 303 396 5.2E-32 T 28-03-2018 CU254_RS01940 b85f9b135c1ad45af38d8d1dd1fed4a5 397 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 397 58.885 T 28-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CU254_RS01940 b85f9b135c1ad45af38d8d1dd1fed4a5 397 Gene3D G3DSA:2.40.30.10 208 302 2.0E-30 T 28-03-2018 CU254_RS01940 b85f9b135c1ad45af38d8d1dd1fed4a5 397 Pfam PF03143 Elongation factor Tu C-terminal domain 302 395 1.1E-31 T 28-03-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal CU254_RS01940 b85f9b135c1ad45af38d8d1dd1fed4a5 397 Gene3D G3DSA:3.40.50.300 77 205 1.4E-30 T 28-03-2018 CU254_RS01940 b85f9b135c1ad45af38d8d1dd1fed4a5 397 Gene3D G3DSA:3.40.50.300 2 76 3.1E-11 T 28-03-2018 CU254_RS01940 b85f9b135c1ad45af38d8d1dd1fed4a5 397 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 53 68 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site CU254_RS13730 3b6d95ac9720d4c69b65f7f4b86eacb5 252 Gene3D G3DSA:2.40.10.10 61 123 9.7E-17 T 28-03-2018 CU254_RS13730 3b6d95ac9720d4c69b65f7f4b86eacb5 252 SMART SM00020 28 245 4.8E-68 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CU254_RS13730 3b6d95ac9720d4c69b65f7f4b86eacb5 252 Gene3D G3DSA:2.40.10.10 124 251 3.3E-40 T 28-03-2018 CU254_RS13730 3b6d95ac9720d4c69b65f7f4b86eacb5 252 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 112 126 2.6E-10 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CU254_RS13730 3b6d95ac9720d4c69b65f7f4b86eacb5 252 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 199 211 2.6E-10 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CU254_RS13730 3b6d95ac9720d4c69b65f7f4b86eacb5 252 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 56 71 2.6E-10 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CU254_RS13730 3b6d95ac9720d4c69b65f7f4b86eacb5 252 Gene3D G3DSA:2.40.10.10 29 60 1.0E-11 T 28-03-2018 CU254_RS13730 3b6d95ac9720d4c69b65f7f4b86eacb5 252 SUPERFAMILY SSF50494 14 247 3.25E-66 T 28-03-2018 IPR009003 Peptidase S1, PA clan CU254_RS13730 3b6d95ac9720d4c69b65f7f4b86eacb5 252 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 200 211 - T 28-03-2018 IPR033116 Serine proteases, trypsin family, serine active site CU254_RS13730 3b6d95ac9720d4c69b65f7f4b86eacb5 252 Pfam PF00089 Trypsin 29 243 7.4E-55 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CU254_RS37650 0a7553867652f75d9419a2edd33b115e 760 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 26 757 9.4E-251 T 28-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CU254_RS37650 0a7553867652f75d9419a2edd33b115e 760 SUPERFAMILY SSF55326 23 207 1.38E-48 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CU254_RS37650 0a7553867652f75d9419a2edd33b115e 760 SUPERFAMILY SSF56042 214 447 6.88E-53 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CU254_RS37650 0a7553867652f75d9419a2edd33b115e 760 SUPERFAMILY SSF56042 593 759 4.93E-38 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CU254_RS37650 0a7553867652f75d9419a2edd33b115e 760 SUPERFAMILY SSF55326 416 587 8.37E-53 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CU254_RS37650 0a7553867652f75d9419a2edd33b115e 760 PIRSF PIRSF001587 7 760 4.7E-278 T 28-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CU254_RS37650 0a7553867652f75d9419a2edd33b115e 760 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 760 302.095 T 28-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CU254_RS37650 0a7553867652f75d9419a2edd33b115e 760 Gene3D G3DSA:3.90.650.10 589 760 1.2E-37 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CU254_RS37650 0a7553867652f75d9419a2edd33b115e 760 Gene3D G3DSA:3.90.650.10 194 390 4.1E-36 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CU254_RS37650 0a7553867652f75d9419a2edd33b115e 760 Pfam PF00586 AIR synthase related protein, N-terminal domain 100 201 3.5E-22 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CU254_RS37650 0a7553867652f75d9419a2edd33b115e 760 Pfam PF00586 AIR synthase related protein, N-terminal domain 476 580 6.4E-22 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CU254_RS37650 0a7553867652f75d9419a2edd33b115e 760 Gene3D G3DSA:3.30.1330.10 26 193 4.6E-53 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CU254_RS37650 0a7553867652f75d9419a2edd33b115e 760 Gene3D G3DSA:3.30.1330.10 416 585 2.6E-45 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CU254_RS37650 0a7553867652f75d9419a2edd33b115e 760 Pfam PF02769 AIR synthase related protein, C-terminal domain 594 731 4.6E-19 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CU254_RS37650 0a7553867652f75d9419a2edd33b115e 760 Pfam PF02769 AIR synthase related protein, C-terminal domain 215 374 2.3E-32 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CU254_RS38035 942ddc5a9129a345dc80810732655b35 255 SUPERFAMILY SSF47413 26 77 7.41E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS38035 942ddc5a9129a345dc80810732655b35 255 Gene3D G3DSA:1.10.260.40 2 88 2.7E-15 T 28-03-2018 CU254_RS38035 942ddc5a9129a345dc80810732655b35 255 SMART SM00530 8 80 8.2E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS38035 942ddc5a9129a345dc80810732655b35 255 Pfam PF13560 Helix-turn-helix domain 4 83 6.9E-17 T 28-03-2018 CU254_RS32335 31d61b174923ed0e23cb5852b468d1cb 506 SUPERFAMILY SSF55785 182 294 1.05E-5 T 28-03-2018 IPR000014 PAS domain CU254_RS32335 31d61b174923ed0e23cb5852b468d1cb 506 SUPERFAMILY SSF55874 360 479 1.83E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS32335 31d61b174923ed0e23cb5852b468d1cb 506 Gene3D G3DSA:3.30.450.20 176 294 1.4E-11 T 28-03-2018 CU254_RS32335 31d61b174923ed0e23cb5852b468d1cb 506 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 400 502 3.4E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS32335 31d61b174923ed0e23cb5852b468d1cb 506 Pfam PF12282 Signal transduction histidine kinase 4 152 4.8E-53 T 28-03-2018 IPR022066 Signal transduction histidine kinase CU254_RS32335 31d61b174923ed0e23cb5852b468d1cb 506 Pfam PF08448 PAS fold 180 289 7.4E-10 T 28-03-2018 IPR013656 PAS fold-4 CU254_RS32335 31d61b174923ed0e23cb5852b468d1cb 506 SMART SM00387 397 504 1.7E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS32335 31d61b174923ed0e23cb5852b468d1cb 506 Gene3D G3DSA:3.30.565.10 295 503 1.6E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS32335 31d61b174923ed0e23cb5852b468d1cb 506 Pfam PF07568 Histidine kinase 303 370 1.9E-22 T 28-03-2018 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain CU254_RS06765 f9707ffcfe0594ab73dd90e422e389fe 347 SMART SM00849 38 253 1.5E-24 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS06765 f9707ffcfe0594ab73dd90e422e389fe 347 SUPERFAMILY SSF56281 8 344 9.07E-56 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS06765 f9707ffcfe0594ab73dd90e422e389fe 347 Gene3D G3DSA:3.60.15.10 17 281 1.3E-38 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS06765 f9707ffcfe0594ab73dd90e422e389fe 347 Pfam PF00753 Metallo-beta-lactamase superfamily 37 253 1.9E-26 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS30815 df7b4ebf3b4695615f1a9c4ba284d051 406 Gene3D G3DSA:3.30.70.270 225 406 3.7E-56 T 28-03-2018 CU254_RS30815 df7b4ebf3b4695615f1a9c4ba284d051 406 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 228 399 3.1E-47 T 28-03-2018 IPR000160 GGDEF domain CU254_RS30815 df7b4ebf3b4695615f1a9c4ba284d051 406 Pfam PF00990 Diguanylate cyclase, GGDEF domain 232 395 1.1E-43 T 28-03-2018 IPR000160 GGDEF domain CU254_RS30815 df7b4ebf3b4695615f1a9c4ba284d051 406 SUPERFAMILY SSF55073 238 400 1.57E-46 T 28-03-2018 IPR029787 Nucleotide cyclase CU254_RS30815 df7b4ebf3b4695615f1a9c4ba284d051 406 SMART SM00267 221 399 4.4E-58 T 28-03-2018 IPR000160 GGDEF domain CU254_RS40265 0508d90d86bb8137c87238efc263d72f 243 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS40265 0508d90d86bb8137c87238efc263d72f 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 3.4E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS40265 0508d90d86bb8137c87238efc263d72f 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 3.4E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS40265 0508d90d86bb8137c87238efc263d72f 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 3.4E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS40265 0508d90d86bb8137c87238efc263d72f 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 3.4E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS40265 0508d90d86bb8137c87238efc263d72f 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 225 3.4E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS40265 0508d90d86bb8137c87238efc263d72f 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 3.4E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS40265 0508d90d86bb8137c87238efc263d72f 243 Gene3D G3DSA:3.40.50.720 1 47 3.2E-12 T 28-03-2018 CU254_RS40265 0508d90d86bb8137c87238efc263d72f 243 Gene3D G3DSA:3.40.50.720 48 243 5.2E-62 T 28-03-2018 CU254_RS40265 0508d90d86bb8137c87238efc263d72f 243 SUPERFAMILY SSF51735 6 242 2.04E-77 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS40265 0508d90d86bb8137c87238efc263d72f 243 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 241 1.2E-61 T 28-03-2018 CU254_RS40265 0508d90d86bb8137c87238efc263d72f 243 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 182 4.0E-7 T 28-03-2018 CU254_RS40265 0508d90d86bb8137c87238efc263d72f 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 7.0E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS40265 0508d90d86bb8137c87238efc263d72f 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 7.0E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS40265 0508d90d86bb8137c87238efc263d72f 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 7.0E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS05990 344b28390cb4f6bed73e7384d941d5f1 399 SUPERFAMILY SSF52540 18 61 1.32E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS05990 344b28390cb4f6bed73e7384d941d5f1 399 Gene3D G3DSA:3.40.50.300 30 391 4.8E-4 T 28-03-2018 CU254_RS05785 45db93d8dcbfe8e58c9afbf5ddab35e1 402 SUPERFAMILY SSF51905 9 181 3.14E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS05785 45db93d8dcbfe8e58c9afbf5ddab35e1 402 SUPERFAMILY SSF51905 284 355 3.14E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS05785 45db93d8dcbfe8e58c9afbf5ddab35e1 402 Gene3D G3DSA:3.50.50.60 4 378 5.1E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS05785 45db93d8dcbfe8e58c9afbf5ddab35e1 402 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 160 175 4.0E-19 T 28-03-2018 CU254_RS05785 45db93d8dcbfe8e58c9afbf5ddab35e1 402 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 303 319 4.0E-19 T 28-03-2018 CU254_RS05785 45db93d8dcbfe8e58c9afbf5ddab35e1 402 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 288 303 4.0E-19 T 28-03-2018 CU254_RS05785 45db93d8dcbfe8e58c9afbf5ddab35e1 402 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 10 32 4.0E-19 T 28-03-2018 CU254_RS05785 45db93d8dcbfe8e58c9afbf5ddab35e1 402 Pfam PF01494 FAD binding domain 9 346 1.1E-42 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CU254_RS03885 a38a32ffecd19e9ef17865bc0f586d57 362 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 57 362 1.8E-65 T 28-03-2018 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 CU254_RS03885 a38a32ffecd19e9ef17865bc0f586d57 362 Gene3D G3DSA:1.20.58.340 295 362 1.2E-20 T 28-03-2018 CU254_RS03885 a38a32ffecd19e9ef17865bc0f586d57 362 Gene3D G3DSA:3.30.460.20 28 170 6.7E-39 T 28-03-2018 CU254_RS03885 a38a32ffecd19e9ef17865bc0f586d57 362 Pfam PF01544 CorA-like Mg2+ transporter protein 64 358 1.1E-67 T 28-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 CU254_RS03885 a38a32ffecd19e9ef17865bc0f586d57 362 SUPERFAMILY SSF143865 33 295 9.29E-70 T 28-03-2018 CU254_RS03885 a38a32ffecd19e9ef17865bc0f586d57 362 SUPERFAMILY SSF144083 297 359 4.45E-21 T 28-03-2018 CU254_RS03885 a38a32ffecd19e9ef17865bc0f586d57 362 Gene3D G3DSA:1.20.58.340 178 294 4.3E-36 T 28-03-2018 CU254_RS05695 ca368d33735a3e9af0f216bdaf19c8be 388 Gene3D G3DSA:3.20.80.10 171 377 3.3E-80 T 28-03-2018 IPR011256 Regulatory factor, effector binding domain CU254_RS05695 ca368d33735a3e9af0f216bdaf19c8be 388 SUPERFAMILY SSF46785 8 172 1.57E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS05695 ca368d33735a3e9af0f216bdaf19c8be 388 Pfam PF03551 Transcriptional regulator PadR-like family 11 81 1.0E-10 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CU254_RS05695 ca368d33735a3e9af0f216bdaf19c8be 388 Gene3D G3DSA:1.10.10.10 3 95 1.3E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS05695 ca368d33735a3e9af0f216bdaf19c8be 388 SUPERFAMILY SSF55136 300 377 5.41E-11 T 28-03-2018 CU254_RS05695 ca368d33735a3e9af0f216bdaf19c8be 388 Pfam PF06445 GyrI-like small molecule binding domain 195 373 1.2E-23 T 28-03-2018 IPR029442 GyrI-like small molecule binding domain CU254_RS07950 2a19739f25dac8a39a33dc1a87f7e45d 357 Pfam PF01979 Amidohydrolase family 164 345 4.0E-9 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CU254_RS07950 2a19739f25dac8a39a33dc1a87f7e45d 357 SUPERFAMILY SSF51556 46 320 3.96E-57 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS07950 2a19739f25dac8a39a33dc1a87f7e45d 357 Gene3D G3DSA:2.30.40.10 10 60 0.001 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS07950 2a19739f25dac8a39a33dc1a87f7e45d 357 Gene3D G3DSA:3.20.20.140 61 318 3.9E-34 T 28-03-2018 CU254_RS02150 549f8b6ac953c80b6d478ddb7d23e841 339 Gene3D G3DSA:1.10.287.850 27 105 1.0E-9 T 28-03-2018 CU254_RS02150 549f8b6ac953c80b6d478ddb7d23e841 339 Pfam PF06013 Proteins of 100 residues with WXG 34 110 1.5E-6 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CU254_RS02150 549f8b6ac953c80b6d478ddb7d23e841 339 SUPERFAMILY SSF140453 32 110 4.58E-7 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CU254_RS02150 549f8b6ac953c80b6d478ddb7d23e841 339 Gene3D G3DSA:1.10.287.1060 106 172 0.15 T 28-03-2018 CU254_RS23010 3744479df126a6aba743f2687d59472b 123 Gene3D G3DSA:1.10.10.10 4 123 2.4E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS23010 3744479df126a6aba743f2687d59472b 123 Pfam PF00196 Bacterial regulatory proteins, luxR family 70 115 3.4E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS23010 3744479df126a6aba743f2687d59472b 123 SMART SM00421 60 117 7.7E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS23010 3744479df126a6aba743f2687d59472b 123 SUPERFAMILY SSF46894 49 123 2.55E-13 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS37090 3f72ac66bbd57e5ca3074047fa9cb989 118 SUPERFAMILY SSF82607 11 103 5.89E-29 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CU254_RS37090 3f72ac66bbd57e5ca3074047fa9cb989 118 PIRSF PIRSF004555 7 114 3.8E-35 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CU254_RS37090 3f72ac66bbd57e5ca3074047fa9cb989 118 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 10 96 4.2E-24 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CU254_RS37090 3f72ac66bbd57e5ca3074047fa9cb989 118 Pfam PF02575 YbaB/EbfC DNA-binding family 15 104 3.3E-34 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CU254_RS37090 3f72ac66bbd57e5ca3074047fa9cb989 118 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 9 103 21.39 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CU254_RS37090 3f72ac66bbd57e5ca3074047fa9cb989 118 Gene3D G3DSA:3.30.1310.10 3 114 8.8E-38 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CU254_RS04670 8ee751ea36b59f7aff574f9e4de313ef 401 Gene3D G3DSA:1.25.40.10 170 400 6.5E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS04670 8ee751ea36b59f7aff574f9e4de313ef 401 Pfam PF08281 Sigma-70, region 4 110 160 1.8E-7 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS04670 8ee751ea36b59f7aff574f9e4de313ef 401 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 6 162 4.3E-14 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS04670 8ee751ea36b59f7aff574f9e4de313ef 401 Pfam PF04542 Sigma-70 region 2 10 75 8.1E-13 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS04670 8ee751ea36b59f7aff574f9e4de313ef 401 SUPERFAMILY SSF88946 6 87 1.77E-14 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS04670 8ee751ea36b59f7aff574f9e4de313ef 401 Gene3D G3DSA:1.10.10.10 71 163 4.5E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS04670 8ee751ea36b59f7aff574f9e4de313ef 401 SUPERFAMILY SSF88659 104 162 8.97E-9 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS04670 8ee751ea36b59f7aff574f9e4de313ef 401 Gene3D G3DSA:1.10.1740.10 2 70 7.0E-16 T 28-03-2018 CU254_RS39695 57055054d36553bdadda60ad1ce0a5d0 440 Pfam PF00232 Glycosyl hydrolase family 1 4 439 6.0E-139 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CU254_RS39695 57055054d36553bdadda60ad1ce0a5d0 440 TIGRFAM TIGR03356 BGL: beta-galactosidase 6 433 3.5E-168 T 28-03-2018 IPR017736 Glycoside hydrolase, family 1, beta-glucosidase GO:0008422|GO:0030245 KEGG: 00460+3.2.1.21|KEGG: 00500+3.2.1.21|KEGG: 00940+3.2.1.21|MetaCyc: PWY-3121|MetaCyc: PWY-5176|MetaCyc: PWY-6002|MetaCyc: PWY-6788|MetaCyc: PWY-7091|MetaCyc: PWY-7092 CU254_RS39695 57055054d36553bdadda60ad1ce0a5d0 440 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 10 24 - T 28-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site CU254_RS39695 57055054d36553bdadda60ad1ce0a5d0 440 SUPERFAMILY SSF51445 5 439 1.16E-152 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS39695 57055054d36553bdadda60ad1ce0a5d0 440 PRINTS PR00131 Glycosyl hydrolase family 1 signature 366 377 2.1E-21 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CU254_RS39695 57055054d36553bdadda60ad1ce0a5d0 440 PRINTS PR00131 Glycosyl hydrolase family 1 signature 411 423 2.1E-21 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CU254_RS39695 57055054d36553bdadda60ad1ce0a5d0 440 PRINTS PR00131 Glycosyl hydrolase family 1 signature 387 404 2.1E-21 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CU254_RS39695 57055054d36553bdadda60ad1ce0a5d0 440 PRINTS PR00131 Glycosyl hydrolase family 1 signature 345 353 2.1E-21 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CU254_RS39695 57055054d36553bdadda60ad1ce0a5d0 440 PRINTS PR00131 Glycosyl hydrolase family 1 signature 280 294 2.1E-21 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CU254_RS39695 57055054d36553bdadda60ad1ce0a5d0 440 Gene3D G3DSA:3.20.20.80 3 440 2.0E-154 T 28-03-2018 CU254_RS20455 b16aa724e65a5bb81128f39a1a2d816a 166 SUPERFAMILY SSF109854 3 161 1.3E-35 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CU254_RS20455 b16aa724e65a5bb81128f39a1a2d816a 166 Gene3D G3DSA:1.20.120.450 2 166 2.1E-29 T 28-03-2018 CU254_RS20455 b16aa724e65a5bb81128f39a1a2d816a 166 Pfam PF04978 Protein of unknown function (DUF664) 22 162 1.0E-36 T 28-03-2018 IPR007061 Protein of unknown function DUF664 CU254_RS23045 f0b22a7f4494fd9af760fb9bfbb59eb6 433 Gene3D G3DSA:3.40.462.10 180 397 7.9E-49 T 28-03-2018 IPR016170 Vanillyl-alcohol oxidase/Cytokinin dehydrogenase C-terminal domain CU254_RS23045 f0b22a7f4494fd9af760fb9bfbb59eb6 433 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 14 47 - T 28-03-2018 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 CU254_RS23045 f0b22a7f4494fd9af760fb9bfbb59eb6 433 PIRSF PIRSF000136 1 433 3.2E-113 T 28-03-2018 IPR010031 L-gulonolactone/D-arabinono-1,4-lactone oxidase GO:0016899|GO:0055114 CU254_RS23045 f0b22a7f4494fd9af760fb9bfbb59eb6 433 Gene3D G3DSA:3.30.465.10 68 179 1.3E-28 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CU254_RS23045 f0b22a7f4494fd9af760fb9bfbb59eb6 433 Pfam PF01565 FAD binding domain 14 148 3.7E-24 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CU254_RS23045 f0b22a7f4494fd9af760fb9bfbb59eb6 433 Gene3D G3DSA:3.30.43.10 1 66 1.5E-13 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CU254_RS23045 f0b22a7f4494fd9af760fb9bfbb59eb6 433 TIGRFAM TIGR01679 bact_FAD_ox: FAD-linked oxidoreductase 3 431 3.3E-120 T 28-03-2018 CU254_RS23045 f0b22a7f4494fd9af760fb9bfbb59eb6 433 Pfam PF04030 D-arabinono-1,4-lactone oxidase 173 429 3.6E-71 T 28-03-2018 IPR007173 D-arabinono-1,4-lactone oxidase GO:0003885|GO:0016020|GO:0055114 CU254_RS23045 f0b22a7f4494fd9af760fb9bfbb59eb6 433 SUPERFAMILY SSF56176 2 179 5.14E-46 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CU254_RS26990 6a7741e0e2ff88f829ef9893ce18766c 180 Pfam PF12840 Helix-turn-helix domain 22 79 2.4E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS26990 6a7741e0e2ff88f829ef9893ce18766c 180 SMART SM00418 22 152 0.0014 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS26990 6a7741e0e2ff88f829ef9893ce18766c 180 Gene3D G3DSA:1.10.10.10 12 158 3.1E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS26990 6a7741e0e2ff88f829ef9893ce18766c 180 SUPERFAMILY SSF46785 18 153 3.52E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS24350 ce9e40551f0c840d22c200d17d35d294 140 SUPERFAMILY SSF55811 2 119 1.49E-21 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CU254_RS24350 ce9e40551f0c840d22c200d17d35d294 140 Pfam PF00293 NUDIX domain 1 115 5.0E-16 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CU254_RS24350 ce9e40551f0c840d22c200d17d35d294 140 Gene3D G3DSA:3.90.79.10 1 130 3.6E-21 T 28-03-2018 CU254_RS24350 ce9e40551f0c840d22c200d17d35d294 140 ProSitePatterns PS00893 Nudix box signature. 26 47 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CU254_RS16780 bac70ad859f017d974f14294d5b6f106 164 Gene3D G3DSA:2.30.110.10 20 164 1.4E-39 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS16780 bac70ad859f017d974f14294d5b6f106 164 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 55 162 2.2E-36 T 28-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CU254_RS16780 bac70ad859f017d974f14294d5b6f106 164 Pfam PF04075 F420H(2)-dependent quinone reductase 27 163 7.4E-40 T 28-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CU254_RS32805 ba58d56dce43bc7e15f0385a76fe4183 250 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 110 124 3.0E-13 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CU254_RS32805 ba58d56dce43bc7e15f0385a76fe4183 250 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 55 70 3.0E-13 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CU254_RS32805 ba58d56dce43bc7e15f0385a76fe4183 250 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 193 205 3.0E-13 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CU254_RS32805 ba58d56dce43bc7e15f0385a76fe4183 250 SMART SM00020 28 245 1.2E-36 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CU254_RS32805 ba58d56dce43bc7e15f0385a76fe4183 250 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 65 70 - T 28-03-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 CU254_RS32805 ba58d56dce43bc7e15f0385a76fe4183 250 SUPERFAMILY SSF50494 17 249 4.95E-51 T 28-03-2018 IPR009003 Peptidase S1, PA clan CU254_RS32805 ba58d56dce43bc7e15f0385a76fe4183 250 Gene3D G3DSA:2.40.10.10 64 250 2.1E-42 T 28-03-2018 CU254_RS32805 ba58d56dce43bc7e15f0385a76fe4183 250 Pfam PF00089 Trypsin 29 245 7.0E-38 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CU254_RS32805 ba58d56dce43bc7e15f0385a76fe4183 250 Gene3D G3DSA:2.40.10.10 29 63 4.8E-15 T 28-03-2018 CU254_RS08110 3d37e1cc41886c29cc45d0127b524d5d 783 Gene3D G3DSA:3.60.20.10 217 330 2.5E-23 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CU254_RS08110 3d37e1cc41886c29cc45d0127b524d5d 783 Gene3D G3DSA:3.60.20.10 341 541 3.2E-44 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CU254_RS08110 3d37e1cc41886c29cc45d0127b524d5d 783 Gene3D G3DSA:3.60.20.10 660 769 3.2E-13 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CU254_RS08110 3d37e1cc41886c29cc45d0127b524d5d 783 PIRSF PIRSF001227 3 778 8.3E-194 T 28-03-2018 IPR014395 Penicillin/GL-7-ACA/AHL acylase GO:0016811 CU254_RS08110 3d37e1cc41886c29cc45d0127b524d5d 783 Gene3D G3DSA:1.10.439.10 30 192 1.4E-43 T 28-03-2018 IPR023343 Penicillin amidase type, domain1 GO:0016811 CU254_RS08110 3d37e1cc41886c29cc45d0127b524d5d 783 Pfam PF01804 Penicillin amidase 34 766 2.2E-188 T 28-03-2018 IPR002692 Penicillin/GL-7-ACA/AHL/aculeacin-A acylase GO:0016787|GO:0017000 CU254_RS08110 3d37e1cc41886c29cc45d0127b524d5d 783 Gene3D G3DSA:1.10.1400.10 542 659 1.6E-22 T 28-03-2018 CU254_RS08110 3d37e1cc41886c29cc45d0127b524d5d 783 SUPERFAMILY SSF56235 30 777 2.14E-191 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CU254_RS21900 3fa933cbf0e22f88048aee4bd0f433a3 204 SUPERFAMILY SSF46689 3 82 1.1E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS21900 3fa933cbf0e22f88048aee4bd0f433a3 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 50 1.5E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS21900 3fa933cbf0e22f88048aee4bd0f433a3 204 Gene3D G3DSA:1.10.357.10 1 195 2.2E-21 T 28-03-2018 CU254_RS12770 0783a75cd85fdd6b030af8d6e05d1011 444 Gene3D G3DSA:3.40.640.10 17 260 4.1E-48 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS12770 0783a75cd85fdd6b030af8d6e05d1011 444 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 30 361 5.3E-97 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CU254_RS12770 0783a75cd85fdd6b030af8d6e05d1011 444 Gene3D G3DSA:3.90.1150.10 261 430 2.9E-25 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS12770 0783a75cd85fdd6b030af8d6e05d1011 444 SUPERFAMILY SSF53383 24 361 2.69E-90 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS12770 0783a75cd85fdd6b030af8d6e05d1011 444 PIRSF PIRSF000390 18 418 4.5E-95 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CU254_RS28625 8a6f020d971aa3bb7a71e4613f8e6591 238 Pfam PF13398 Peptidase M50B-like 28 227 5.7E-56 T 28-03-2018 CU254_RS04655 8043d613d66ead500af364b777f6f448 202 Gene3D G3DSA:1.10.357.10 71 200 2.2E-14 T 28-03-2018 CU254_RS04655 8043d613d66ead500af364b777f6f448 202 SUPERFAMILY SSF46689 11 95 1.25E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS04655 8043d613d66ead500af364b777f6f448 202 Gene3D G3DSA:1.10.10.60 1 70 1.5E-18 T 28-03-2018 CU254_RS04655 8043d613d66ead500af364b777f6f448 202 SUPERFAMILY SSF48498 92 198 8.67E-17 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS04655 8043d613d66ead500af364b777f6f448 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 72 1.2E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS04655 8043d613d66ead500af364b777f6f448 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 2.2E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS04655 8043d613d66ead500af364b777f6f448 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 2.2E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS30620 683d632fa90259adf4b0f70f8db4b23a 270 SUPERFAMILY SSF53597 28 155 9.56E-32 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CU254_RS30620 683d632fa90259adf4b0f70f8db4b23a 270 SUPERFAMILY SSF53597 183 269 9.56E-32 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CU254_RS30620 683d632fa90259adf4b0f70f8db4b23a 270 Gene3D G3DSA:3.40.430.10 23 270 2.8E-42 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CU254_RS30620 683d632fa90259adf4b0f70f8db4b23a 270 Pfam PF01872 RibD C-terminal domain 28 263 2.1E-26 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CU254_RS33675 f45190c11296d683d5ebb53710a563fe 1186 SMART SM00982 1033 1130 6.6E-38 T 28-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 CU254_RS33675 f45190c11296d683d5ebb53710a563fe 1186 Pfam PF00271 Helicase conserved C-terminal domain 834 933 1.0E-14 T 28-03-2018 IPR001650 Helicase, C-terminal CU254_RS33675 f45190c11296d683d5ebb53710a563fe 1186 SUPERFAMILY SSF52540 806 1014 2.13E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS33675 f45190c11296d683d5ebb53710a563fe 1186 SUPERFAMILY SSF52540 374 474 2.5E-6 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS33675 f45190c11296d683d5ebb53710a563fe 1186 SUPERFAMILY SSF143517 1023 1181 1.44E-33 T 28-03-2018 CU254_RS33675 f45190c11296d683d5ebb53710a563fe 1186 SUPERFAMILY SSF52540 37 365 7.62E-70 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS33675 f45190c11296d683d5ebb53710a563fe 1186 Gene3D G3DSA:3.40.50.300 815 980 1.9E-23 T 28-03-2018 CU254_RS33675 f45190c11296d683d5ebb53710a563fe 1186 Gene3D G3DSA:3.40.50.300 346 803 5.2E-36 T 28-03-2018 CU254_RS33675 f45190c11296d683d5ebb53710a563fe 1186 SMART SM00487 624 816 7.2E-30 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CU254_RS33675 f45190c11296d683d5ebb53710a563fe 1186 Pfam PF02559 CarD-like/TRCF domain 500 599 2.1E-31 T 28-03-2018 IPR003711 CarD-like/TRCF domain CU254_RS33675 f45190c11296d683d5ebb53710a563fe 1186 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 34 1131 28.436 T 28-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 CU254_RS33675 f45190c11296d683d5ebb53710a563fe 1186 Pfam PF03461 TRCF domain 1034 1115 1.3E-23 T 28-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 CU254_RS33675 f45190c11296d683d5ebb53710a563fe 1186 SMART SM01058 499 600 2.3E-48 T 28-03-2018 IPR003711 CarD-like/TRCF domain CU254_RS33675 f45190c11296d683d5ebb53710a563fe 1186 SUPERFAMILY SSF52540 550 807 3.13E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS33675 f45190c11296d683d5ebb53710a563fe 1186 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 160 1106 0.0 T 28-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 CU254_RS33675 f45190c11296d683d5ebb53710a563fe 1186 SUPERFAMILY SSF141259 494 572 1.96E-18 T 28-03-2018 IPR003711 CarD-like/TRCF domain CU254_RS33675 f45190c11296d683d5ebb53710a563fe 1186 SMART SM00490 850 934 1.4E-17 T 28-03-2018 IPR001650 Helicase, C-terminal CU254_RS33675 f45190c11296d683d5ebb53710a563fe 1186 Pfam PF00270 DEAD/DEAH box helicase 649 790 1.7E-17 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CU254_RS01760 24ca183c0db10fd33b054b001a070874 392 SUPERFAMILY SSF52540 7 232 3.9E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS01760 24ca183c0db10fd33b054b001a070874 392 Pfam PF00005 ABC transporter 21 168 9.0E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS01760 24ca183c0db10fd33b054b001a070874 392 SMART SM00382 29 225 1.5E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS01760 24ca183c0db10fd33b054b001a070874 392 Gene3D G3DSA:3.40.50.300 1 329 5.4E-53 T 28-03-2018 CU254_RS01760 24ca183c0db10fd33b054b001a070874 392 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS02915 56019ba50d2b5afcf6aca65ca60c2769 262 Gene3D G3DSA:1.10.3720.10 1 253 5.9E-39 T 28-03-2018 CU254_RS02915 56019ba50d2b5afcf6aca65ca60c2769 262 SUPERFAMILY SSF161098 2 262 1.87E-59 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS02915 56019ba50d2b5afcf6aca65ca60c2769 262 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 74 256 2.3E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS22010 510cc506bcf8dbeeb18c00a9b626a856 646 SUPERFAMILY SSF51445 133 635 2.45E-133 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS22010 510cc506bcf8dbeeb18c00a9b626a856 646 Pfam PF02446 4-alpha-glucanotransferase 138 621 8.2E-114 T 28-03-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 CU254_RS22010 510cc506bcf8dbeeb18c00a9b626a856 646 Gene3D G3DSA:3.20.20.80 131 637 1.4E-155 T 28-03-2018 CU254_RS22010 510cc506bcf8dbeeb18c00a9b626a856 646 TIGRFAM TIGR00217 malQ: 4-alpha-glucanotransferase 103 630 2.2E-87 T 28-03-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 CU254_RS07060 f6941a286ad836b94b66b1f2a691b870 159 Gene3D G3DSA:2.60.120.10 3 155 1.1E-25 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS07060 f6941a286ad836b94b66b1f2a691b870 159 Pfam PF05995 Cysteine dioxygenase type I 28 149 4.7E-22 T 28-03-2018 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|Reactome: R-HSA-1614558 CU254_RS07060 f6941a286ad836b94b66b1f2a691b870 159 SUPERFAMILY SSF51182 9 149 7.5E-30 T 28-03-2018 IPR011051 RmlC-like cupin domain CU254_RS16030 72ce2af720496d8e9d69c4dd2879529f 358 Gene3D G3DSA:2.40.10.10 174 257 7.3E-19 T 28-03-2018 CU254_RS16030 72ce2af720496d8e9d69c4dd2879529f 358 Gene3D G3DSA:2.40.10.10 258 345 5.1E-19 T 28-03-2018 CU254_RS16030 72ce2af720496d8e9d69c4dd2879529f 358 PIRSF PIRSF001134 2 358 2.4E-109 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CU254_RS16030 72ce2af720496d8e9d69c4dd2879529f 358 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 201 215 1.6E-44 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CU254_RS16030 72ce2af720496d8e9d69c4dd2879529f 358 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 323 337 1.6E-44 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CU254_RS16030 72ce2af720496d8e9d69c4dd2879529f 358 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 259 279 1.6E-44 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CU254_RS16030 72ce2af720496d8e9d69c4dd2879529f 358 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 299 322 1.6E-44 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CU254_RS16030 72ce2af720496d8e9d69c4dd2879529f 358 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 280 297 1.6E-44 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CU254_RS16030 72ce2af720496d8e9d69c4dd2879529f 358 Gene3D G3DSA:3.30.300.50 41 98 1.2E-17 T 28-03-2018 IPR035070 Streptogrisin prodomain CU254_RS16030 72ce2af720496d8e9d69c4dd2879529f 358 SUPERFAMILY SSF50494 180 351 2.12E-32 T 28-03-2018 IPR009003 Peptidase S1, PA clan CU254_RS16030 72ce2af720496d8e9d69c4dd2879529f 358 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 308 319 - T 28-03-2018 IPR033116 Serine proteases, trypsin family, serine active site CU254_RS16030 72ce2af720496d8e9d69c4dd2879529f 358 Pfam PF00089 Trypsin 199 348 1.5E-9 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CU254_RS16030 72ce2af720496d8e9d69c4dd2879529f 358 Pfam PF02983 Alpha-lytic protease prodomain 105 155 2.4E-11 T 28-03-2018 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 CU254_RS16030 72ce2af720496d8e9d69c4dd2879529f 358 Gene3D G3DSA:3.30.300.50 99 168 7.2E-17 T 28-03-2018 IPR035070 Streptogrisin prodomain CU254_RS22480 f3e4d56f1b98168409946b1635ab4ffd 856 SUPERFAMILY SSF54991 759 855 9.42E-26 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CU254_RS22480 f3e4d56f1b98168409946b1635ab4ffd 856 Pfam PF03147 Ferredoxin-fold anticodon binding domain 762 855 1.8E-22 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CU254_RS22480 f3e4d56f1b98168409946b1635ab4ffd 856 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 849 38.747 T 28-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CU254_RS22480 f3e4d56f1b98168409946b1635ab4ffd 856 SMART SM00874 436 509 2.2E-18 T 28-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CU254_RS22480 f3e4d56f1b98168409946b1635ab4ffd 856 Gene3D G3DSA:3.50.40.10 231 431 4.9E-71 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CU254_RS22480 f3e4d56f1b98168409946b1635ab4ffd 856 SUPERFAMILY SSF56037 235 430 3.14E-64 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CU254_RS22480 f3e4d56f1b98168409946b1635ab4ffd 856 SUPERFAMILY SSF50249 107 224 1.66E-26 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CU254_RS22480 f3e4d56f1b98168409946b1635ab4ffd 856 SUPERFAMILY SSF50249 43 76 1.66E-26 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CU254_RS22480 f3e4d56f1b98168409946b1635ab4ffd 856 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 107 855 2.3E-158 T 28-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CU254_RS22480 f3e4d56f1b98168409946b1635ab4ffd 856 Gene3D G3DSA:2.40.50.140 36 194 1.4E-43 T 28-03-2018 CU254_RS22480 f3e4d56f1b98168409946b1635ab4ffd 856 Gene3D G3DSA:3.30.930.10 526 751 6.9E-35 T 28-03-2018 CU254_RS22480 f3e4d56f1b98168409946b1635ab4ffd 856 SMART SM00896 762 855 1.1E-39 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CU254_RS22480 f3e4d56f1b98168409946b1635ab4ffd 856 SMART SM00873 247 420 2.3E-80 T 28-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CU254_RS22480 f3e4d56f1b98168409946b1635ab4ffd 856 SUPERFAMILY SSF46955 437 513 1.46E-12 T 28-03-2018 IPR009061 Putative DNA-binding domain CU254_RS22480 f3e4d56f1b98168409946b1635ab4ffd 856 Pfam PF03484 tRNA synthetase B5 domain 443 509 4.9E-12 T 28-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CU254_RS22480 f3e4d56f1b98168409946b1635ab4ffd 856 Pfam PF03483 B3/4 domain 247 419 4.7E-62 T 28-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CU254_RS22480 f3e4d56f1b98168409946b1635ab4ffd 856 Pfam PF01588 Putative tRNA binding domain 107 179 7.7E-10 T 28-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 CU254_RS22480 f3e4d56f1b98168409946b1635ab4ffd 856 SUPERFAMILY SSF55681 505 621 9.44E-41 T 28-03-2018 CU254_RS22480 f3e4d56f1b98168409946b1635ab4ffd 856 SUPERFAMILY SSF55681 651 750 9.44E-41 T 28-03-2018 CU254_RS22480 f3e4d56f1b98168409946b1635ab4ffd 856 Gene3D G3DSA:3.30.70.380 759 855 8.7E-24 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CU254_RS22480 f3e4d56f1b98168409946b1635ab4ffd 856 Gene3D G3DSA:3.30.56.10 435 513 2.1E-15 T 28-03-2018 CU254_RS28180 801c58e1e4080dbb7817ef0d40ebd156 1291 Pfam PF00271 Helicase conserved C-terminal domain 284 401 1.5E-10 T 28-03-2018 IPR001650 Helicase, C-terminal CU254_RS28180 801c58e1e4080dbb7817ef0d40ebd156 1291 Gene3D G3DSA:3.40.50.300 248 422 8.4E-48 T 28-03-2018 CU254_RS28180 801c58e1e4080dbb7817ef0d40ebd156 1291 SMART SM00487 70 254 1.6E-26 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CU254_RS28180 801c58e1e4080dbb7817ef0d40ebd156 1291 Pfam PF00270 DEAD/DEAH box helicase 83 228 9.2E-7 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CU254_RS28180 801c58e1e4080dbb7817ef0d40ebd156 1291 SUPERFAMILY SSF52540 71 592 2.07E-110 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS28180 801c58e1e4080dbb7817ef0d40ebd156 1291 SMART SM00382 87 382 3.6E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS28180 801c58e1e4080dbb7817ef0d40ebd156 1291 Pfam PF07717 Oligonucleotide/oligosaccharide-binding (OB)-fold 617 693 3.9E-19 T 28-03-2018 IPR011709 Domain of unknown function DUF1605 CU254_RS28180 801c58e1e4080dbb7817ef0d40ebd156 1291 SMART SM00490 302 402 9.7E-14 T 28-03-2018 IPR001650 Helicase, C-terminal CU254_RS28180 801c58e1e4080dbb7817ef0d40ebd156 1291 SMART SM00847 462 554 2.4E-36 T 28-03-2018 IPR007502 Helicase-associated domain GO:0004386 CU254_RS28180 801c58e1e4080dbb7817ef0d40ebd156 1291 TIGRFAM TIGR01967 DEAH_box_HrpA: RNA helicase HrpA 12 1287 0.0 T 28-03-2018 IPR010222 RNA helicase HrpA GO:0004004 CU254_RS28180 801c58e1e4080dbb7817ef0d40ebd156 1291 Pfam PF04408 Helicase associated domain (HA2) 464 552 5.6E-18 T 28-03-2018 IPR007502 Helicase-associated domain GO:0004386 CU254_RS28180 801c58e1e4080dbb7817ef0d40ebd156 1291 Gene3D G3DSA:3.40.50.300 71 230 1.4E-28 T 28-03-2018 CU254_RS28180 801c58e1e4080dbb7817ef0d40ebd156 1291 Pfam PF11898 Domain of unknown function (DUF3418) 707 1287 1.5E-234 T 28-03-2018 IPR024590 RNA helicase HrpA, C-terminal CU254_RS12030 93869af50b7007c2ea295f5f5a72c4f0 650 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 277 284 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CU254_RS12030 93869af50b7007c2ea295f5f5a72c4f0 650 Pfam PF02785 Biotin carboxylase C-terminal domain 325 438 1.0E-31 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CU254_RS12030 93869af50b7007c2ea295f5f5a72c4f0 650 SUPERFAMILY SSF52440 1 113 3.02E-43 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CU254_RS12030 93869af50b7007c2ea295f5f5a72c4f0 650 SMART SM00878 325 438 7.3E-48 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CU254_RS12030 93869af50b7007c2ea295f5f5a72c4f0 650 Gene3D G3DSA:3.40.50.20 1 117 5.9E-48 T 28-03-2018 CU254_RS12030 93869af50b7007c2ea295f5f5a72c4f0 650 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 142 313 2.1E-65 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CU254_RS12030 93869af50b7007c2ea295f5f5a72c4f0 650 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 6.7E-40 T 28-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CU254_RS12030 93869af50b7007c2ea295f5f5a72c4f0 650 Pfam PF00364 Biotin-requiring enzyme 583 645 1.5E-18 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CU254_RS12030 93869af50b7007c2ea295f5f5a72c4f0 650 Gene3D G3DSA:3.30.1490.20 118 193 3.2E-16 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CU254_RS12030 93869af50b7007c2ea295f5f5a72c4f0 650 Gene3D G3DSA:2.40.50.100 446 595 1.3E-6 T 28-03-2018 CU254_RS12030 93869af50b7007c2ea295f5f5a72c4f0 650 SUPERFAMILY SSF51246 320 440 7.32E-34 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CU254_RS12030 93869af50b7007c2ea295f5f5a72c4f0 650 Gene3D G3DSA:2.40.50.100 596 646 6.2E-14 T 28-03-2018 CU254_RS12030 93869af50b7007c2ea295f5f5a72c4f0 650 SUPERFAMILY SSF56059 83 317 5.3E-61 T 28-03-2018 CU254_RS12030 93869af50b7007c2ea295f5f5a72c4f0 650 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 603 620 - T 28-03-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CU254_RS12030 93869af50b7007c2ea295f5f5a72c4f0 650 SUPERFAMILY SSF51230 578 646 5.56E-22 T 28-03-2018 IPR011053 Single hybrid motif CU254_RS12030 93869af50b7007c2ea295f5f5a72c4f0 650 Gene3D G3DSA:3.30.470.20 194 445 2.8E-101 T 28-03-2018 CU254_RS40995 d73a146b462395f6f53483dc082bccd8 249 Pfam PF13394 4Fe-4S single cluster domain 44 132 2.7E-12 T 28-03-2018 CU254_RS40995 d73a146b462395f6f53483dc082bccd8 249 Pfam PF04055 Radical SAM superfamily 50 133 2.6E-8 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CU254_RS40995 d73a146b462395f6f53483dc082bccd8 249 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 22 246 35.431 T 28-03-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 CU254_RS40995 d73a146b462395f6f53483dc082bccd8 249 SUPERFAMILY SSF102114 40 206 6.28E-14 T 28-03-2018 CU254_RS40995 d73a146b462395f6f53483dc082bccd8 249 PIRSF PIRSF000370 20 249 9.0E-46 T 28-03-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 CU254_RS40995 d73a146b462395f6f53483dc082bccd8 249 Gene3D G3DSA:3.20.20.70 41 154 2.1E-16 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS05720 a426dfae0e24bf55e49b28d61491e841 365 Gene3D G3DSA:3.40.50.2000 1 173 2.3E-31 T 28-03-2018 CU254_RS05720 a426dfae0e24bf55e49b28d61491e841 365 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 193 345 3.6E-32 T 28-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CU254_RS05720 a426dfae0e24bf55e49b28d61491e841 365 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 8 147 9.7E-31 T 28-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CU254_RS05720 a426dfae0e24bf55e49b28d61491e841 365 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 8 358 29.295 T 28-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CU254_RS05720 a426dfae0e24bf55e49b28d61491e841 365 Gene3D G3DSA:3.40.50.2000 174 352 1.5E-34 T 28-03-2018 CU254_RS05720 a426dfae0e24bf55e49b28d61491e841 365 SUPERFAMILY SSF53756 7 359 1.49E-89 T 28-03-2018 CU254_RS32110 963f7e6555bb99c626f97dd9bf28087a 309 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 142 163 - T 28-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 CU254_RS32110 963f7e6555bb99c626f97dd9bf28087a 309 SUPERFAMILY SSF51735 114 238 5.98E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS32110 963f7e6555bb99c626f97dd9bf28087a 309 SMART SM00829 10 306 2.6E-41 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CU254_RS32110 963f7e6555bb99c626f97dd9bf28087a 309 SUPERFAMILY SSF50129 1 141 6.39E-33 T 28-03-2018 IPR011032 GroES-like CU254_RS32110 963f7e6555bb99c626f97dd9bf28087a 309 Gene3D G3DSA:3.90.180.10 229 309 7.3E-8 T 28-03-2018 CU254_RS32110 963f7e6555bb99c626f97dd9bf28087a 309 Gene3D G3DSA:3.40.50.720 153 228 9.9E-15 T 28-03-2018 CU254_RS32110 963f7e6555bb99c626f97dd9bf28087a 309 Pfam PF13602 Zinc-binding dehydrogenase 184 306 2.0E-29 T 28-03-2018 CU254_RS32110 963f7e6555bb99c626f97dd9bf28087a 309 Gene3D G3DSA:3.90.180.10 1 152 3.4E-46 T 28-03-2018 CU254_RS28585 fb2d18a13ac9b5d0d1bebe97d34c5ba1 406 Gene3D G3DSA:2.10.10.20 357 401 2.7E-17 T 28-03-2018 CU254_RS28585 fb2d18a13ac9b5d0d1bebe97d34c5ba1 406 SUPERFAMILY SSF51445 51 306 1.99E-17 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS28585 fb2d18a13ac9b5d0d1bebe97d34c5ba1 406 SUPERFAMILY SSF51055 353 406 2.09E-15 T 28-03-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 CU254_RS28585 fb2d18a13ac9b5d0d1bebe97d34c5ba1 406 Gene3D G3DSA:3.20.20.80 38 339 5.6E-22 T 28-03-2018 CU254_RS28585 fb2d18a13ac9b5d0d1bebe97d34c5ba1 406 SMART SM00495 358 403 3.5E-17 T 28-03-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 CU254_RS37000 b51172336125c36ede95cae06d3f0c47 437 Gene3D G3DSA:1.10.1740.10 27 113 2.1E-12 T 28-03-2018 CU254_RS37000 b51172336125c36ede95cae06d3f0c47 437 Pfam PF08281 Sigma-70, region 4 139 190 2.2E-9 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS37000 b51172336125c36ede95cae06d3f0c47 437 Gene3D G3DSA:1.10.10.10 143 246 1.0E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS37000 b51172336125c36ede95cae06d3f0c47 437 Pfam PF04542 Sigma-70 region 2 43 109 2.2E-8 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS37000 b51172336125c36ede95cae06d3f0c47 437 SUPERFAMILY SSF88946 37 122 1.33E-10 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS37000 b51172336125c36ede95cae06d3f0c47 437 SUPERFAMILY SSF88659 133 192 9.35E-11 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS26950 ae74430bb98d3b9ca6db6029823a73de 770 Gene3D G3DSA:3.40.50.740 340 630 4.0E-48 T 28-03-2018 CU254_RS26950 ae74430bb98d3b9ca6db6029823a73de 770 Pfam PF00384 Molybdopterin oxidoreductase 125 505 1.8E-27 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS26950 ae74430bb98d3b9ca6db6029823a73de 770 TIGRFAM TIGR01701 Fdhalpha-like: oxidoreductase alpha (molybdopterin) subunit 24 766 9.5E-293 T 28-03-2018 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 CU254_RS26950 ae74430bb98d3b9ca6db6029823a73de 770 Gene3D G3DSA:3.40.50.740 126 339 2.2E-38 T 28-03-2018 CU254_RS26950 ae74430bb98d3b9ca6db6029823a73de 770 SUPERFAMILY SSF53706 58 624 2.88E-144 T 28-03-2018 CU254_RS26950 ae74430bb98d3b9ca6db6029823a73de 770 Pfam PF01568 Molydopterin dinucleotide binding domain 654 760 1.9E-10 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CU254_RS26950 ae74430bb98d3b9ca6db6029823a73de 770 SUPERFAMILY SSF50692 647 767 2.94E-16 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain CU254_RS26950 ae74430bb98d3b9ca6db6029823a73de 770 PIRSF PIRSF000144 5 770 0.0 T 28-03-2018 CU254_RS26950 ae74430bb98d3b9ca6db6029823a73de 770 Gene3D G3DSA:2.40.40.20 651 770 1.8E-23 T 28-03-2018 CU254_RS17340 ee946f4b9f66eed508dfbbc500c5f02a 458 Gene3D G3DSA:1.20.1250.20 1 182 5.5E-30 T 28-03-2018 CU254_RS17340 ee946f4b9f66eed508dfbbc500c5f02a 458 Gene3D G3DSA:1.20.1250.20 243 456 2.0E-28 T 28-03-2018 CU254_RS17340 ee946f4b9f66eed508dfbbc500c5f02a 458 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 1 403 5.6E-85 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CU254_RS17340 ee946f4b9f66eed508dfbbc500c5f02a 458 Pfam PF07690 Major Facilitator Superfamily 2 392 4.4E-51 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS17340 ee946f4b9f66eed508dfbbc500c5f02a 458 PRINTS PR01036 Tetracycline resistance protein TetB signature 91 111 5.0E-8 T 28-03-2018 CU254_RS17340 ee946f4b9f66eed508dfbbc500c5f02a 458 PRINTS PR01036 Tetracycline resistance protein TetB signature 343 363 5.0E-8 T 28-03-2018 CU254_RS17340 ee946f4b9f66eed508dfbbc500c5f02a 458 PRINTS PR01036 Tetracycline resistance protein TetB signature 121 145 5.0E-8 T 28-03-2018 CU254_RS17340 ee946f4b9f66eed508dfbbc500c5f02a 458 PRINTS PR01036 Tetracycline resistance protein TetB signature 146 170 5.0E-8 T 28-03-2018 CU254_RS17340 ee946f4b9f66eed508dfbbc500c5f02a 458 SUPERFAMILY SSF103473 2 178 3.01E-65 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS17340 ee946f4b9f66eed508dfbbc500c5f02a 458 SUPERFAMILY SSF103473 232 441 3.01E-65 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS11175 d0a640386c6d70775cf126b5e0b70f32 123 PRINTS PR00421 Thioredoxin family signature 29 38 2.2E-7 T 28-03-2018 CU254_RS11175 d0a640386c6d70775cf126b5e0b70f32 123 PRINTS PR00421 Thioredoxin family signature 21 29 2.2E-7 T 28-03-2018 CU254_RS11175 d0a640386c6d70775cf126b5e0b70f32 123 PRINTS PR00421 Thioredoxin family signature 68 79 2.2E-7 T 28-03-2018 CU254_RS11175 d0a640386c6d70775cf126b5e0b70f32 123 PIRSF PIRSF000077 1 104 6.3E-29 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CU254_RS11175 d0a640386c6d70775cf126b5e0b70f32 123 ProSitePatterns PS00194 Thioredoxin family active site. 22 40 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CU254_RS11175 d0a640386c6d70775cf126b5e0b70f32 123 Gene3D G3DSA:3.40.30.10 1 123 1.6E-36 T 28-03-2018 CU254_RS11175 d0a640386c6d70775cf126b5e0b70f32 123 SUPERFAMILY SSF52833 3 103 3.4E-34 T 28-03-2018 IPR012336 Thioredoxin-like fold CU254_RS11175 d0a640386c6d70775cf126b5e0b70f32 123 Pfam PF00085 Thioredoxin 3 101 1.9E-28 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 CU254_RS11175 d0a640386c6d70775cf126b5e0b70f32 123 TIGRFAM TIGR01068 thioredoxin: thioredoxin 7 102 2.8E-31 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CU254_RS14345 9953bd0e039a52c86b9384b510ccb9af 262 TIGRFAM TIGR04504 SDR_subfam_2: SDR family mycofactocin-dependent oxidoreductase 2 261 4.9E-110 T 28-03-2018 IPR030981 SDR family mycofactocin-dependent oxidoreductase CU254_RS14345 9953bd0e039a52c86b9384b510ccb9af 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 8.2E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS14345 9953bd0e039a52c86b9384b510ccb9af 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 8.2E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS14345 9953bd0e039a52c86b9384b510ccb9af 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 224 244 8.2E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS14345 9953bd0e039a52c86b9384b510ccb9af 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 187 204 8.2E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS14345 9953bd0e039a52c86b9384b510ccb9af 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 185 8.2E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS14345 9953bd0e039a52c86b9384b510ccb9af 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 156 8.2E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS14345 9953bd0e039a52c86b9384b510ccb9af 262 Gene3D G3DSA:3.40.50.720 1 262 4.4E-61 T 28-03-2018 CU254_RS14345 9953bd0e039a52c86b9384b510ccb9af 262 SUPERFAMILY SSF51735 2 260 2.11E-63 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS14345 9953bd0e039a52c86b9384b510ccb9af 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 166 185 8.7E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS14345 9953bd0e039a52c86b9384b510ccb9af 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 89 100 8.7E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS14345 9953bd0e039a52c86b9384b510ccb9af 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 154 8.7E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS14345 9953bd0e039a52c86b9384b510ccb9af 262 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 8 260 4.4E-52 T 28-03-2018 CU254_RS14345 9953bd0e039a52c86b9384b510ccb9af 262 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 153 181 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS03585 bbc0349c198bba601b11d11f3dff89de 464 TIGRFAM TIGR03553 F420_FbiB_CTERM: F420 biosynthesis protein FbiB, C-terminal domain 271 464 9.0E-91 T 28-03-2018 IPR019943 Coenzyme F420 biosynthesis protein FbiB, C-terminal GO:0016881 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 CU254_RS03585 bbc0349c198bba601b11d11f3dff89de 464 Gene3D G3DSA:3.30.1330.100 150 243 4.3E-27 T 28-03-2018 CU254_RS03585 bbc0349c198bba601b11d11f3dff89de 464 SUPERFAMILY SSF144010 29 263 1.28E-66 T 28-03-2018 CU254_RS03585 bbc0349c198bba601b11d11f3dff89de 464 SUPERFAMILY SSF55469 270 463 7.85E-39 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CU254_RS03585 bbc0349c198bba601b11d11f3dff89de 464 TIGRFAM TIGR01916 F420_cofE: coenzyme F420-0:L-glutamate ligase 28 258 3.8E-77 T 28-03-2018 IPR008225 Coenzyme F420:L-glutamate ligase GO:0043773|GO:0046872|GO:0051188 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 CU254_RS03585 bbc0349c198bba601b11d11f3dff89de 464 Pfam PF00881 Nitroreductase family 275 444 1.8E-28 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CU254_RS03585 bbc0349c198bba601b11d11f3dff89de 464 Pfam PF01996 F420-0:Gamma-glutamyl ligase 36 235 4.3E-39 T 28-03-2018 IPR002847 Coenzyme F420:L-glutamate ligase-like domain KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 CU254_RS03585 bbc0349c198bba601b11d11f3dff89de 464 Hamap MF_01259 Coenzyme F420:L-glutamate ligase [fbiB]. 33 464 51.358 T 28-03-2018 IPR023661 Coenzyme F420:L-glutamate ligase, bacteria GO:0043773|GO:0046872|GO:0051188 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 CU254_RS03585 bbc0349c198bba601b11d11f3dff89de 464 Gene3D G3DSA:3.90.1660.10 60 149 1.0E-27 T 28-03-2018 CU254_RS03585 bbc0349c198bba601b11d11f3dff89de 464 Gene3D G3DSA:3.40.109.10 270 461 2.9E-39 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CU254_RS10395 bdbd682285ff855cf5c295ad939ecd7e 302 SUPERFAMILY SSF54637 13 167 2.29E-20 T 28-03-2018 IPR029069 HotDog domain CU254_RS10395 bdbd682285ff855cf5c295ad939ecd7e 302 Pfam PF13452 N-terminal half of MaoC dehydratase 21 156 1.0E-19 T 28-03-2018 CU254_RS10395 bdbd682285ff855cf5c295ad939ecd7e 302 Gene3D G3DSA:3.10.129.10 3 175 8.5E-34 T 28-03-2018 CU254_RS10395 bdbd682285ff855cf5c295ad939ecd7e 302 SUPERFAMILY SSF50249 173 295 2.74E-23 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CU254_RS10395 bdbd682285ff855cf5c295ad939ecd7e 302 Gene3D G3DSA:2.40.50.140 227 291 5.9E-20 T 28-03-2018 CU254_RS10395 bdbd682285ff855cf5c295ad939ecd7e 302 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 224 287 9.0E-22 T 28-03-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal CU254_RS24490 1921858fdf5e0138c062a64810041eaa 283 Gene3D G3DSA:1.20.5.620 115 151 0.0074 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain CU254_RS24490 1921858fdf5e0138c062a64810041eaa 283 Gene3D G3DSA:1.20.5.620 152 213 7.0E-8 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain CU254_RS24490 1921858fdf5e0138c062a64810041eaa 283 Pfam PF05103 DivIVA protein 3 66 1.8E-12 T 28-03-2018 IPR007793 DivIVA family CU254_RS24490 1921858fdf5e0138c062a64810041eaa 283 Gene3D G3DSA:1.20.5.170 30 70 3.8E-4 T 28-03-2018 CU254_RS24490 1921858fdf5e0138c062a64810041eaa 283 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 39 7.2E-15 T 28-03-2018 IPR019933 DivIVA domain CU254_RS19865 05b9213b611224fc9b163881122f27b4 296 TIGRFAM TIGR01505 tartro_sem_red: 2-hydroxy-3-oxopropionate reductase 3 290 3.6E-104 T 28-03-2018 IPR006398 2-hydroxy-3-oxopropionate reductase GO:0008679|GO:0046487|GO:0055114 KEGG: 00630+1.1.1.60 CU254_RS19865 05b9213b611224fc9b163881122f27b4 296 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 6 19 - T 28-03-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 CU254_RS19865 05b9213b611224fc9b163881122f27b4 296 PIRSF PIRSF000103 1 294 2.2E-78 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CU254_RS19865 05b9213b611224fc9b163881122f27b4 296 SUPERFAMILY SSF51735 3 163 1.59E-48 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS19865 05b9213b611224fc9b163881122f27b4 296 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 165 284 6.7E-34 T 28-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CU254_RS19865 05b9213b611224fc9b163881122f27b4 296 Gene3D G3DSA:3.40.50.720 1 163 4.2E-38 T 28-03-2018 CU254_RS19865 05b9213b611224fc9b163881122f27b4 296 SUPERFAMILY SSF48179 163 291 7.82E-36 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CU254_RS19865 05b9213b611224fc9b163881122f27b4 296 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 162 3.0E-50 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CU254_RS19865 05b9213b611224fc9b163881122f27b4 296 Gene3D G3DSA:1.10.1040.10 164 291 4.8E-31 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CU254_RS26725 fbacbaafd87ea899b38140a6cd196306 185 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 121 184 6.0E-16 T 28-03-2018 IPR004509 Competence protein ComEA, helix-hairpin-helix domain CU254_RS26725 fbacbaafd87ea899b38140a6cd196306 185 Gene3D G3DSA:1.10.150.20 55 140 3.8E-8 T 28-03-2018 CU254_RS26725 fbacbaafd87ea899b38140a6cd196306 185 Gene3D G3DSA:1.10.150.310 141 185 4.3E-16 T 28-03-2018 CU254_RS26725 fbacbaafd87ea899b38140a6cd196306 185 SUPERFAMILY SSF47781 110 184 1.56E-29 T 28-03-2018 IPR010994 RuvA domain 2-like CU254_RS26725 fbacbaafd87ea899b38140a6cd196306 185 SMART SM00278 132 151 0.034 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CU254_RS26725 fbacbaafd87ea899b38140a6cd196306 185 SMART SM00278 162 181 19.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CU254_RS26725 fbacbaafd87ea899b38140a6cd196306 185 Pfam PF12836 Helix-hairpin-helix motif 121 183 4.1E-22 T 28-03-2018 CU254_RS26725 fbacbaafd87ea899b38140a6cd196306 185 Pfam PF10531 SLBB domain 51 102 4.1E-13 T 28-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS11650 a7819296844221e90256e6627c1656f9 146 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 16 94 1.0E-10 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CU254_RS11650 a7819296844221e90256e6627c1656f9 146 Gene3D G3DSA:2.30.110.10 1 145 1.2E-21 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS11650 a7819296844221e90256e6627c1656f9 146 SUPERFAMILY SSF50475 1 137 2.06E-23 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS11650 a7819296844221e90256e6627c1656f9 146 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 11 138 3.7E-30 T 28-03-2018 IPR019920 F420-binding domain, putative CU254_RS10835 15020f45800c46cb3a40ab738a6b10fd 710 Pfam PF00005 ABC transporter 408 557 1.0E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS10835 15020f45800c46cb3a40ab738a6b10fd 710 Pfam PF00005 ABC transporter 40 197 5.0E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS10835 15020f45800c46cb3a40ab738a6b10fd 710 SMART SM00382 416 607 1.0E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS10835 15020f45800c46cb3a40ab738a6b10fd 710 SMART SM00382 47 247 7.1E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS10835 15020f45800c46cb3a40ab738a6b10fd 710 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 249 314 5.5E-19 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CU254_RS10835 15020f45800c46cb3a40ab738a6b10fd 710 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 609 669 2.4E-14 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CU254_RS10835 15020f45800c46cb3a40ab738a6b10fd 710 Gene3D G3DSA:3.40.50.300 15 352 6.9E-69 T 28-03-2018 CU254_RS10835 15020f45800c46cb3a40ab738a6b10fd 710 Gene3D G3DSA:3.40.50.300 376 710 1.1E-78 T 28-03-2018 CU254_RS10835 15020f45800c46cb3a40ab738a6b10fd 710 SUPERFAMILY SSF52540 380 629 4.72E-72 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS10835 15020f45800c46cb3a40ab738a6b10fd 710 SUPERFAMILY SSF52540 18 267 9.8E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS10835 15020f45800c46cb3a40ab738a6b10fd 710 ProSitePatterns PS00211 ABC transporters family signature. 530 544 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS10835 15020f45800c46cb3a40ab738a6b10fd 710 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 248 327 1.0E-22 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CU254_RS10835 15020f45800c46cb3a40ab738a6b10fd 710 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 607 703 4.0E-23 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CU254_RS10835 15020f45800c46cb3a40ab738a6b10fd 710 ProSitePatterns PS00211 ABC transporters family signature. 170 184 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS20290 0763bfb7da701659340c684593761f65 408 PIRSF PIRSF036426 153 408 1.8E-90 T 28-03-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CU254_RS20290 0763bfb7da701659340c684593761f65 408 PIRSF PIRSF036426 3 158 1.6E-29 T 28-03-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CU254_RS20290 0763bfb7da701659340c684593761f65 408 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 168 379 4.0E-50 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CU254_RS20290 0763bfb7da701659340c684593761f65 408 Pfam PF13241 Putative NAD(P)-binding 10 117 8.8E-23 T 28-03-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CU254_RS20290 0763bfb7da701659340c684593761f65 408 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 11 132 4.1E-18 T 28-03-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CU254_RS20290 0763bfb7da701659340c684593761f65 408 SUPERFAMILY SSF53790 166 402 1.23E-70 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CU254_RS20290 0763bfb7da701659340c684593761f65 408 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 168 402 2.3E-79 T 28-03-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CU254_RS20290 0763bfb7da701659340c684593761f65 408 Gene3D G3DSA:3.40.1010.10 165 290 5.8E-35 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CU254_RS20290 0763bfb7da701659340c684593761f65 408 SUPERFAMILY SSF51735 5 106 4.53E-18 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS20290 0763bfb7da701659340c684593761f65 408 Gene3D G3DSA:3.30.950.10 291 407 8.2E-37 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CU254_RS20290 0763bfb7da701659340c684593761f65 408 Gene3D G3DSA:3.40.50.720 6 132 1.8E-17 T 28-03-2018 CU254_RS12090 19a840a2110fa64ccf75a7651b15781b 548 Pfam PF00664 ABC transporter transmembrane region 17 275 6.3E-19 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CU254_RS12090 19a840a2110fa64ccf75a7651b15781b 548 SUPERFAMILY SSF52540 317 542 1.78E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS12090 19a840a2110fa64ccf75a7651b15781b 548 Gene3D G3DSA:1.20.1560.10 2 310 9.3E-41 T 28-03-2018 CU254_RS12090 19a840a2110fa64ccf75a7651b15781b 548 SUPERFAMILY SSF90123 8 315 5.76E-43 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CU254_RS12090 19a840a2110fa64ccf75a7651b15781b 548 Gene3D G3DSA:3.40.50.300 322 547 9.3E-46 T 28-03-2018 CU254_RS12090 19a840a2110fa64ccf75a7651b15781b 548 SMART SM00382 348 527 2.8E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS12090 19a840a2110fa64ccf75a7651b15781b 548 Pfam PF00005 ABC transporter 339 481 4.8E-19 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS15170 e1b09e8afb726a504b41cc66c6a308b4 793 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 77 324 9.0E-30 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CU254_RS15170 e1b09e8afb726a504b41cc66c6a308b4 793 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 511 617 1.6E-25 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CU254_RS15170 e1b09e8afb726a504b41cc66c6a308b4 793 Pfam PF00122 E1-E2 ATPase 109 282 6.4E-38 T 28-03-2018 CU254_RS15170 e1b09e8afb726a504b41cc66c6a308b4 793 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 305 311 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CU254_RS15170 e1b09e8afb726a504b41cc66c6a308b4 793 SUPERFAMILY SSF81665 204 297 1.44E-61 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CU254_RS15170 e1b09e8afb726a504b41cc66c6a308b4 793 SUPERFAMILY SSF81665 587 787 1.44E-61 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CU254_RS15170 e1b09e8afb726a504b41cc66c6a308b4 793 SUPERFAMILY SSF81665 8 106 1.44E-61 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CU254_RS15170 e1b09e8afb726a504b41cc66c6a308b4 793 Gene3D G3DSA:2.70.150.10 6 202 6.9E-29 T 28-03-2018 CU254_RS15170 e1b09e8afb726a504b41cc66c6a308b4 793 Pfam PF00690 Cation transporter/ATPase, N-terminus 9 63 1.8E-5 T 28-03-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 CU254_RS15170 e1b09e8afb726a504b41cc66c6a308b4 793 SUPERFAMILY SSF56784 299 588 2.48E-34 T 28-03-2018 IPR023214 HAD-like domain CU254_RS15170 e1b09e8afb726a504b41cc66c6a308b4 793 Gene3D G3DSA:3.40.1110.10 266 464 7.8E-19 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CU254_RS15170 e1b09e8afb726a504b41cc66c6a308b4 793 Gene3D G3DSA:1.20.1110.10 473 792 5.4E-45 T 28-03-2018 CU254_RS15170 e1b09e8afb726a504b41cc66c6a308b4 793 Pfam PF00702 haloacid dehalogenase-like hydrolase 299 552 7.0E-17 T 28-03-2018 CU254_RS15170 e1b09e8afb726a504b41cc66c6a308b4 793 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 460 470 1.7E-25 T 28-03-2018 CU254_RS15170 e1b09e8afb726a504b41cc66c6a308b4 793 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 561 573 1.7E-25 T 28-03-2018 CU254_RS15170 e1b09e8afb726a504b41cc66c6a308b4 793 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 153 167 1.7E-25 T 28-03-2018 CU254_RS15170 e1b09e8afb726a504b41cc66c6a308b4 793 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 538 557 1.7E-25 T 28-03-2018 CU254_RS15170 e1b09e8afb726a504b41cc66c6a308b4 793 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 303 317 1.7E-25 T 28-03-2018 CU254_RS15170 e1b09e8afb726a504b41cc66c6a308b4 793 SUPERFAMILY SSF81653 109 200 4.05E-20 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CU254_RS18820 553df0d9b25d7a8c31ddfa6743ff34bf 451 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 233 265 - T 28-03-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 CU254_RS18820 553df0d9b25d7a8c31ddfa6743ff34bf 451 SUPERFAMILY SSF53720 25 432 1.18E-68 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CU254_RS18820 553df0d9b25d7a8c31ddfa6743ff34bf 451 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 37 431 2.5E-130 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CU254_RS18820 553df0d9b25d7a8c31ddfa6743ff34bf 451 Gene3D G3DSA:3.40.50.1980 230 376 2.5E-59 T 28-03-2018 CU254_RS18820 553df0d9b25d7a8c31ddfa6743ff34bf 451 Gene3D G3DSA:3.40.50.1980 30 229 2.1E-64 T 28-03-2018 CU254_RS18820 553df0d9b25d7a8c31ddfa6743ff34bf 451 PIRSF PIRSF000099 15 435 2.1E-115 T 28-03-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CU254_RS18820 553df0d9b25d7a8c31ddfa6743ff34bf 451 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 1 432 32.162 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CU254_RS18820 553df0d9b25d7a8c31ddfa6743ff34bf 451 PRINTS PR00083 Histidinol dehydrogenase signature 255 274 2.7E-65 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CU254_RS18820 553df0d9b25d7a8c31ddfa6743ff34bf 451 PRINTS PR00083 Histidinol dehydrogenase signature 204 229 2.7E-65 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CU254_RS18820 553df0d9b25d7a8c31ddfa6743ff34bf 451 PRINTS PR00083 Histidinol dehydrogenase signature 366 384 2.7E-65 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CU254_RS18820 553df0d9b25d7a8c31ddfa6743ff34bf 451 PRINTS PR00083 Histidinol dehydrogenase signature 37 61 2.7E-65 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CU254_RS18820 553df0d9b25d7a8c31ddfa6743ff34bf 451 PRINTS PR00083 Histidinol dehydrogenase signature 233 254 2.7E-65 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CU254_RS18820 553df0d9b25d7a8c31ddfa6743ff34bf 451 PRINTS PR00083 Histidinol dehydrogenase signature 111 138 2.7E-65 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CU254_RS18820 553df0d9b25d7a8c31ddfa6743ff34bf 451 PRINTS PR00083 Histidinol dehydrogenase signature 174 200 2.7E-65 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CU254_RS18820 553df0d9b25d7a8c31ddfa6743ff34bf 451 PRINTS PR00083 Histidinol dehydrogenase signature 324 349 2.7E-65 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CU254_RS18820 553df0d9b25d7a8c31ddfa6743ff34bf 451 Pfam PF00815 Histidinol dehydrogenase 28 431 6.3E-128 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CU254_RS18265 cdb575dc99ae18d00237f676beb38f31 452 PIRSF PIRSF018077 1 452 3.8E-182 T 28-03-2018 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 CU254_RS18265 cdb575dc99ae18d00237f676beb38f31 452 TIGRFAM TIGR03686 pupylate_PafA: Pup--protein ligase 3 452 7.3E-235 T 28-03-2018 IPR022279 Pup--protein ligase GO:0010498|GO:0016879|GO:0019941 CU254_RS18265 cdb575dc99ae18d00237f676beb38f31 452 Hamap MF_02111 Pup--protein ligase [pafA]. 1 452 51.223 T 28-03-2018 IPR022279 Pup--protein ligase GO:0010498|GO:0016879|GO:0019941 CU254_RS18265 cdb575dc99ae18d00237f676beb38f31 452 Pfam PF03136 Pup-ligase protein 4 422 1.5E-157 T 28-03-2018 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 CU254_RS22735 12b54065e14c76cdd45c2d4ef56b6307 642 SUPERFAMILY SSF53474 394 641 2.36E-61 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS22735 12b54065e14c76cdd45c2d4ef56b6307 642 Pfam PF00326 Prolyl oligopeptidase family 435 641 2.0E-44 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CU254_RS22735 12b54065e14c76cdd45c2d4ef56b6307 642 Gene3D G3DSA:3.40.50.1820 381 642 5.0E-48 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS22735 12b54065e14c76cdd45c2d4ef56b6307 642 Gene3D G3DSA:2.130.10.150 205 380 8.9E-12 T 28-03-2018 CU254_RS22735 12b54065e14c76cdd45c2d4ef56b6307 642 Gene3D G3DSA:2.130.10.150 46 204 1.7E-20 T 28-03-2018 CU254_RS22735 12b54065e14c76cdd45c2d4ef56b6307 642 Pfam PF07676 WD40-like Beta Propeller Repeat 51 87 4.3E-5 T 28-03-2018 IPR011659 WD40-like Beta Propeller CU254_RS22735 12b54065e14c76cdd45c2d4ef56b6307 642 Pfam PF07676 WD40-like Beta Propeller Repeat 108 130 0.0068 T 28-03-2018 IPR011659 WD40-like Beta Propeller CU254_RS22735 12b54065e14c76cdd45c2d4ef56b6307 642 SUPERFAMILY SSF82171 19 378 9.55E-31 T 28-03-2018 CU254_RS05165 d47002e2fa533257e7b090fa250cbdb6 79 Gene3D G3DSA:3.40.30.10 2 79 4.2E-15 T 28-03-2018 CU254_RS05165 d47002e2fa533257e7b090fa250cbdb6 79 Pfam PF00462 Glutaredoxin 6 64 3.4E-11 T 28-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 CU254_RS05165 d47002e2fa533257e7b090fa250cbdb6 79 SUPERFAMILY SSF52833 6 77 3.13E-13 T 28-03-2018 IPR012336 Thioredoxin-like fold CU254_RS07550 594368aceaf049198ec17d74bb8e891d 393 ProSitePatterns PS00737 Thiolases signature 2. 339 355 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CU254_RS07550 594368aceaf049198ec17d74bb8e891d 393 PIRSF PIRSF000429 1 393 2.8E-130 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CU254_RS07550 594368aceaf049198ec17d74bb8e891d 393 SUPERFAMILY SSF53901 270 391 8.78E-42 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS07550 594368aceaf049198ec17d74bb8e891d 393 Pfam PF00108 Thiolase, N-terminal domain 5 260 9.7E-69 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CU254_RS07550 594368aceaf049198ec17d74bb8e891d 393 ProSitePatterns PS00099 Thiolases active site. 374 387 - T 28-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CU254_RS07550 594368aceaf049198ec17d74bb8e891d 393 Gene3D G3DSA:3.40.47.10 273 390 1.8E-30 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS07550 594368aceaf049198ec17d74bb8e891d 393 SUPERFAMILY SSF53901 3 268 5.76E-78 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS07550 594368aceaf049198ec17d74bb8e891d 393 Pfam PF02803 Thiolase, C-terminal domain 270 391 1.0E-41 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CU254_RS07550 594368aceaf049198ec17d74bb8e891d 393 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 391 2.3E-136 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CU254_RS07550 594368aceaf049198ec17d74bb8e891d 393 Gene3D G3DSA:3.40.47.10 1 272 3.0E-55 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS17070 0a39fce4c1c9363f88f0739c483b2755 429 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 97 160 1.0E-8 T 28-03-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403 CU254_RS17070 0a39fce4c1c9363f88f0739c483b2755 429 Pfam PF01968 Hydantoinase/oxoprolinase 182 257 7.3E-6 T 28-03-2018 IPR002821 Hydantoinase/oxoprolinase GO:0016787 Reactome: R-HSA-174403 CU254_RS35010 1c0b053311bf6f97fb5a3c151c4513cc 246 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 53 69 2.0E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS35010 1c0b053311bf6f97fb5a3c151c4513cc 246 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 39 53 2.0E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS35010 1c0b053311bf6f97fb5a3c151c4513cc 246 Gene3D G3DSA:1.10.10.10 1 80 3.0E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS35010 1c0b053311bf6f97fb5a3c151c4513cc 246 Pfam PF07702 UTRA domain 102 237 4.9E-18 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CU254_RS35010 1c0b053311bf6f97fb5a3c151c4513cc 246 SUPERFAMILY SSF46785 14 83 4.42E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS35010 1c0b053311bf6f97fb5a3c151c4513cc 246 SMART SM00345 20 79 2.5E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS35010 1c0b053311bf6f97fb5a3c151c4513cc 246 Gene3D G3DSA:3.40.1410.10 82 242 1.2E-22 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CU254_RS35010 1c0b053311bf6f97fb5a3c151c4513cc 246 SMART SM00866 98 237 1.0E-8 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CU254_RS35010 1c0b053311bf6f97fb5a3c151c4513cc 246 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 79 2.3E-18 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS35010 1c0b053311bf6f97fb5a3c151c4513cc 246 SUPERFAMILY SSF64288 68 242 2.36E-21 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CU254_RS34240 0bd1ec009f413829853652dcace3e8a0 479 PRINTS PR00344 Bacterial sensor protein C-terminal signature 461 474 1.1E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS34240 0bd1ec009f413829853652dcace3e8a0 479 PRINTS PR00344 Bacterial sensor protein C-terminal signature 437 455 1.1E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS34240 0bd1ec009f413829853652dcace3e8a0 479 PRINTS PR00344 Bacterial sensor protein C-terminal signature 422 432 1.1E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS34240 0bd1ec009f413829853652dcace3e8a0 479 PRINTS PR00344 Bacterial sensor protein C-terminal signature 404 418 1.1E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS34240 0bd1ec009f413829853652dcace3e8a0 479 Gene3D G3DSA:1.10.287.130 244 322 1.6E-12 T 28-03-2018 CU254_RS34240 0bd1ec009f413829853652dcace3e8a0 479 SMART SM00304 201 253 8.0E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS34240 0bd1ec009f413829853652dcace3e8a0 479 SUPERFAMILY SSF158472 204 249 5.23E-6 T 28-03-2018 CU254_RS34240 0bd1ec009f413829853652dcace3e8a0 479 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 366 474 9.9E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS34240 0bd1ec009f413829853652dcace3e8a0 479 SUPERFAMILY SSF47384 237 325 9.61E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS34240 0bd1ec009f413829853652dcace3e8a0 479 SMART SM00387 366 477 9.2E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS34240 0bd1ec009f413829853652dcace3e8a0 479 Gene3D G3DSA:3.30.565.10 328 479 6.5E-40 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS34240 0bd1ec009f413829853652dcace3e8a0 479 Pfam PF00672 HAMP domain 201 247 1.2E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS34240 0bd1ec009f413829853652dcace3e8a0 479 Pfam PF00512 His Kinase A (phospho-acceptor) domain 255 325 1.0E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS34240 0bd1ec009f413829853652dcace3e8a0 479 SUPERFAMILY SSF55874 316 474 3.67E-39 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS34240 0bd1ec009f413829853652dcace3e8a0 479 SMART SM00388 254 326 3.9E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS28870 94f712c7f72e5a33bd996a5a50eb5df8 466 PIRSF PIRSF001386 1 459 6.0E-192 T 28-03-2018 IPR011166 Beta-eliminating lyase family GO:0009072|GO:0016830 KEGG: 00380+4.1.99.1 CU254_RS28870 94f712c7f72e5a33bd996a5a50eb5df8 466 Pfam PF01212 Beta-eliminating lyase 47 423 1.1E-85 T 28-03-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 CU254_RS28870 94f712c7f72e5a33bd996a5a50eb5df8 466 Gene3D G3DSA:3.90.1150.10 273 456 8.2E-68 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS28870 94f712c7f72e5a33bd996a5a50eb5df8 466 Gene3D G3DSA:3.90.1150.10 18 223 4.7E-37 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS28870 94f712c7f72e5a33bd996a5a50eb5df8 466 SUPERFAMILY SSF53383 4 457 7.2E-130 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS19685 934e4c1d7aa56d1f741e49186d201cab 297 Gene3D G3DSA:3.40.50.1820 3 296 1.0E-44 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS19685 934e4c1d7aa56d1f741e49186d201cab 297 SUPERFAMILY SSF53474 4 285 7.36E-44 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS19685 934e4c1d7aa56d1f741e49186d201cab 297 PRINTS PR00412 Epoxide hydrolase signature 30 48 3.6E-6 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS19685 934e4c1d7aa56d1f741e49186d201cab 297 PRINTS PR00412 Epoxide hydrolase signature 264 286 3.6E-6 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS19685 934e4c1d7aa56d1f741e49186d201cab 297 PRINTS PR00412 Epoxide hydrolase signature 53 68 3.6E-6 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS19685 934e4c1d7aa56d1f741e49186d201cab 297 PRINTS PR00412 Epoxide hydrolase signature 99 112 3.6E-6 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS19685 934e4c1d7aa56d1f741e49186d201cab 297 PRINTS PR00412 Epoxide hydrolase signature 231 247 3.6E-6 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS19685 934e4c1d7aa56d1f741e49186d201cab 297 Pfam PF12146 Serine aminopeptidase, S33 24 271 1.1E-19 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 CU254_RS29975 50c85f456792d6b034939ff55fe9116d 179 Pfam PF13302 Acetyltransferase (GNAT) domain 19 153 1.8E-20 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS29975 50c85f456792d6b034939ff55fe9116d 179 SUPERFAMILY SSF55729 15 157 2.47E-29 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS29975 50c85f456792d6b034939ff55fe9116d 179 Gene3D G3DSA:3.40.630.30 13 177 4.0E-24 T 28-03-2018 CU254_RS38305 94160299b845efed70c209b89338f7a0 393 SUPERFAMILY SSF49493 240 293 1.7E-20 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CU254_RS38305 94160299b845efed70c209b89338f7a0 393 SUPERFAMILY SSF49493 140 196 1.7E-20 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CU254_RS38305 94160299b845efed70c209b89338f7a0 393 SUPERFAMILY SSF49493 286 369 2.22E-18 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CU254_RS38305 94160299b845efed70c209b89338f7a0 393 Pfam PF00684 DnaJ central domain 174 234 1.6E-12 T 28-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CU254_RS38305 94160299b845efed70c209b89338f7a0 393 Gene3D G3DSA:1.10.287.110 7 134 2.0E-28 T 28-03-2018 IPR001623 DnaJ domain CU254_RS38305 94160299b845efed70c209b89338f7a0 393 PRINTS PR00625 DnaJ domain signature 12 30 7.5E-22 T 28-03-2018 IPR001623 DnaJ domain CU254_RS38305 94160299b845efed70c209b89338f7a0 393 PRINTS PR00625 DnaJ domain signature 47 67 7.5E-22 T 28-03-2018 IPR001623 DnaJ domain CU254_RS38305 94160299b845efed70c209b89338f7a0 393 PRINTS PR00625 DnaJ domain signature 67 86 7.5E-22 T 28-03-2018 IPR001623 DnaJ domain CU254_RS38305 94160299b845efed70c209b89338f7a0 393 PRINTS PR00625 DnaJ domain signature 30 45 7.5E-22 T 28-03-2018 IPR001623 DnaJ domain CU254_RS38305 94160299b845efed70c209b89338f7a0 393 Pfam PF00226 DnaJ domain 10 72 2.0E-25 T 28-03-2018 IPR001623 DnaJ domain CU254_RS38305 94160299b845efed70c209b89338f7a0 393 Gene3D G3DSA:2.60.260.20 224 281 1.7E-19 T 28-03-2018 CU254_RS38305 94160299b845efed70c209b89338f7a0 393 Pfam PF01556 DnaJ C terminal domain 147 359 4.1E-35 T 28-03-2018 IPR002939 Chaperone DnaJ, C-terminal CU254_RS38305 94160299b845efed70c209b89338f7a0 393 SMART SM00271 9 67 1.1E-26 T 28-03-2018 IPR001623 DnaJ domain CU254_RS38305 94160299b845efed70c209b89338f7a0 393 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 7 389 36.054 T 28-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 CU254_RS38305 94160299b845efed70c209b89338f7a0 393 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 10 376 2.6E-119 T 28-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 CU254_RS38305 94160299b845efed70c209b89338f7a0 393 SUPERFAMILY SSF46565 9 106 7.2E-29 T 28-03-2018 IPR001623 DnaJ domain CU254_RS38305 94160299b845efed70c209b89338f7a0 393 Gene3D G3DSA:2.60.260.20 282 389 7.3E-26 T 28-03-2018 CU254_RS38305 94160299b845efed70c209b89338f7a0 393 Gene3D G3DSA:2.10.230.10 171 223 6.0E-17 T 28-03-2018 CU254_RS38305 94160299b845efed70c209b89338f7a0 393 SUPERFAMILY SSF57938 161 236 1.31E-19 T 28-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CU254_RS14790 b79da6c91855fbf95facbdf5d30805d7 285 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 175 187 7.7E-10 T 28-03-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 CU254_RS14790 b79da6c91855fbf95facbdf5d30805d7 285 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 48 61 7.7E-10 T 28-03-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 CU254_RS14790 b79da6c91855fbf95facbdf5d30805d7 285 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 28 42 7.7E-10 T 28-03-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 CU254_RS14790 b79da6c91855fbf95facbdf5d30805d7 285 PRINTS PR00505 D12 class N6 adenine-specific DNA methyltransferase signature 7 23 7.7E-10 T 28-03-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 CU254_RS14790 b79da6c91855fbf95facbdf5d30805d7 285 Pfam PF02086 D12 class N6 adenine-specific DNA methyltransferase 7 81 3.4E-11 T 28-03-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 CU254_RS14790 b79da6c91855fbf95facbdf5d30805d7 285 Pfam PF02086 D12 class N6 adenine-specific DNA methyltransferase 156 234 2.6E-5 T 28-03-2018 IPR012327 D12 class N6 adenine-specific DNA methyltransferase GO:0009007|GO:0032775 CU254_RS14790 b79da6c91855fbf95facbdf5d30805d7 285 PIRSF PIRSF000398 1 265 2.0E-41 T 28-03-2018 IPR012263 Adenine modification methylase, M.EcoRV-type GO:0009007|GO:0032775 CU254_RS14790 b79da6c91855fbf95facbdf5d30805d7 285 Gene3D G3DSA:3.40.50.150 1 267 5.8E-33 T 28-03-2018 CU254_RS14790 b79da6c91855fbf95facbdf5d30805d7 285 SUPERFAMILY SSF53335 2 261 3.24E-46 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS31265 36bbe7d246dfcd8e598796f49a868640 312 PRINTS PR00126 ATP synthase gamma subunit signature 180 197 3.1E-35 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CU254_RS31265 36bbe7d246dfcd8e598796f49a868640 312 PRINTS PR00126 ATP synthase gamma subunit signature 283 304 3.1E-35 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CU254_RS31265 36bbe7d246dfcd8e598796f49a868640 312 PRINTS PR00126 ATP synthase gamma subunit signature 75 94 3.1E-35 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CU254_RS31265 36bbe7d246dfcd8e598796f49a868640 312 PRINTS PR00126 ATP synthase gamma subunit signature 252 271 3.1E-35 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CU254_RS31265 36bbe7d246dfcd8e598796f49a868640 312 SUPERFAMILY SSF52943 3 305 9.68E-84 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CU254_RS31265 36bbe7d246dfcd8e598796f49a868640 312 Pfam PF00231 ATP synthase 4 305 7.3E-90 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CU254_RS31265 36bbe7d246dfcd8e598796f49a868640 312 Gene3D G3DSA:1.10.287.80 253 300 3.4E-13 T 28-03-2018 CU254_RS31265 36bbe7d246dfcd8e598796f49a868640 312 Gene3D G3DSA:1.10.287.80 3 58 1.3E-12 T 28-03-2018 CU254_RS31265 36bbe7d246dfcd8e598796f49a868640 312 Gene3D G3DSA:1.10.287.80 193 252 2.0E-21 T 28-03-2018 CU254_RS31265 36bbe7d246dfcd8e598796f49a868640 312 Gene3D G3DSA:3.40.1380.10 64 192 4.2E-40 T 28-03-2018 CU254_RS31265 36bbe7d246dfcd8e598796f49a868640 312 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 291 304 - T 28-03-2018 IPR023632 ATP synthase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CU254_RS31265 36bbe7d246dfcd8e598796f49a868640 312 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 3 305 3.6E-100 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CU254_RS31265 36bbe7d246dfcd8e598796f49a868640 312 Hamap MF_00815 ATP synthase gamma chain [atpG]. 2 305 34.765 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CU254_RS29925 6ae2400be27a03d5eb686ca68e8e750b 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 2.3E-17 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS29925 6ae2400be27a03d5eb686ca68e8e750b 197 Gene3D G3DSA:1.10.357.10 1 196 4.7E-35 T 28-03-2018 CU254_RS29925 6ae2400be27a03d5eb686ca68e8e750b 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 2.9E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS29925 6ae2400be27a03d5eb686ca68e8e750b 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 2.9E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS29925 6ae2400be27a03d5eb686ca68e8e750b 197 SUPERFAMILY SSF46689 2 86 4.89E-21 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS16960 0fd5f92a9c96828ed39be415eec977ac 215 PRINTS PR00400 Tetracycline repressor protein signature 84 103 2.0E-15 T 28-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 CU254_RS16960 0fd5f92a9c96828ed39be415eec977ac 215 PRINTS PR00400 Tetracycline repressor protein signature 104 127 2.0E-15 T 28-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 CU254_RS16960 0fd5f92a9c96828ed39be415eec977ac 215 PRINTS PR00400 Tetracycline repressor protein signature 32 55 2.0E-15 T 28-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 CU254_RS16960 0fd5f92a9c96828ed39be415eec977ac 215 PRINTS PR00400 Tetracycline repressor protein signature 200 214 2.0E-15 T 28-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 CU254_RS16960 0fd5f92a9c96828ed39be415eec977ac 215 PRINTS PR00400 Tetracycline repressor protein signature 140 159 2.0E-15 T 28-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 CU254_RS16960 0fd5f92a9c96828ed39be415eec977ac 215 Gene3D G3DSA:1.10.260.40 42 84 6.8E-13 T 28-03-2018 CU254_RS16960 0fd5f92a9c96828ed39be415eec977ac 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 1.2E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS16960 0fd5f92a9c96828ed39be415eec977ac 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 1.2E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS16960 0fd5f92a9c96828ed39be415eec977ac 215 ProSitePatterns PS01081 TetR-type HTH domain signature. 32 63 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CU254_RS16960 0fd5f92a9c96828ed39be415eec977ac 215 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 85 212 7.2E-28 T 28-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 CU254_RS16960 0fd5f92a9c96828ed39be415eec977ac 215 SUPERFAMILY SSF48498 84 211 7.45E-28 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS16960 0fd5f92a9c96828ed39be415eec977ac 215 Gene3D G3DSA:1.10.357.10 85 214 2.1E-23 T 28-03-2018 CU254_RS16960 0fd5f92a9c96828ed39be415eec977ac 215 Gene3D G3DSA:1.10.10.60 6 41 1.5E-16 T 28-03-2018 CU254_RS16960 0fd5f92a9c96828ed39be415eec977ac 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 66 5.9E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS16960 0fd5f92a9c96828ed39be415eec977ac 215 SUPERFAMILY SSF46689 9 80 5.49E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS40725 e4438d0d5fa5be0cbdcc308baedb858a 296 PIRSF PIRSF028756 24 295 2.2E-114 T 28-03-2018 IPR016898 Polyphosphate kinase 2 CU254_RS40725 e4438d0d5fa5be0cbdcc308baedb858a 296 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 51 275 6.7E-100 T 28-03-2018 IPR022488 Polyphosphate kinase-2-related CU254_RS40725 e4438d0d5fa5be0cbdcc308baedb858a 296 Gene3D G3DSA:3.40.50.300 21 296 2.3E-94 T 28-03-2018 CU254_RS40725 e4438d0d5fa5be0cbdcc308baedb858a 296 TIGRFAM TIGR03707 PPK2_P_aer: polyphosphate kinase 2 49 277 1.8E-112 T 28-03-2018 IPR022486 Polyphosphate kinase 2, PA0141 GO:0006793|GO:0008976 CU254_RS40725 e4438d0d5fa5be0cbdcc308baedb858a 296 SUPERFAMILY SSF52540 81 266 3.26E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS21045 a24ad15b2c11366473eb047d80dd9d57 577 Gene3D G3DSA:1.10.3720.10 59 269 9.5E-22 T 28-03-2018 CU254_RS21045 a24ad15b2c11366473eb047d80dd9d57 577 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 255 1.6E-13 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS21045 a24ad15b2c11366473eb047d80dd9d57 577 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 391 574 9.1E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS21045 a24ad15b2c11366473eb047d80dd9d57 577 Gene3D G3DSA:1.10.3720.10 335 575 4.2E-20 T 28-03-2018 CU254_RS21045 a24ad15b2c11366473eb047d80dd9d57 577 SUPERFAMILY SSF161098 371 562 3.27E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS21045 a24ad15b2c11366473eb047d80dd9d57 577 SUPERFAMILY SSF161098 61 256 1.96E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS40125 b56bac07cb8631aad13051947774978c 205 PIRSF PIRSF000709 2 199 2.3E-6 T 28-03-2018 CU254_RS40125 b56bac07cb8631aad13051947774978c 205 SMART SM00855 2 161 6.8E-21 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CU254_RS40125 b56bac07cb8631aad13051947774978c 205 Gene3D G3DSA:3.40.50.1240 1 204 7.2E-45 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CU254_RS40125 b56bac07cb8631aad13051947774978c 205 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 5 14 - T 28-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 CU254_RS40125 b56bac07cb8631aad13051947774978c 205 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 202 5.9E-49 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CU254_RS40125 b56bac07cb8631aad13051947774978c 205 SUPERFAMILY SSF53254 2 202 1.44E-45 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CU254_RS09330 dda2c812dd26a0e8c586755f0eaf7499 411 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 64 390 9.0E-50 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CU254_RS09330 dda2c812dd26a0e8c586755f0eaf7499 411 PIRSF PIRSF001413 8 406 1.4E-152 T 28-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CU254_RS09330 dda2c812dd26a0e8c586755f0eaf7499 411 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 19 401 2.8E-181 T 28-03-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CU254_RS09330 dda2c812dd26a0e8c586755f0eaf7499 411 Gene3D G3DSA:3.40.50.1100 21 210 4.3E-43 T 28-03-2018 CU254_RS09330 dda2c812dd26a0e8c586755f0eaf7499 411 Gene3D G3DSA:3.40.50.1100 211 410 5.8E-42 T 28-03-2018 CU254_RS09330 dda2c812dd26a0e8c586755f0eaf7499 411 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 93 107 - T 28-03-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CU254_RS09330 dda2c812dd26a0e8c586755f0eaf7499 411 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 14 403 50.779 T 28-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CU254_RS09330 dda2c812dd26a0e8c586755f0eaf7499 411 SUPERFAMILY SSF53686 15 402 4.19E-144 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CU254_RS07675 ec7015b1b9d5a5d4ac47efa3db508507 329 Gene3D G3DSA:3.40.50.720 1 125 1.9E-28 T 28-03-2018 CU254_RS07675 ec7015b1b9d5a5d4ac47efa3db508507 329 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 129 233 7.0E-9 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CU254_RS07675 ec7015b1b9d5a5d4ac47efa3db508507 329 SUPERFAMILY SSF51735 2 143 5.2E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS07675 ec7015b1b9d5a5d4ac47efa3db508507 329 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 2 114 1.0E-16 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CU254_RS07675 ec7015b1b9d5a5d4ac47efa3db508507 329 Gene3D G3DSA:3.30.360.10 126 329 9.0E-42 T 28-03-2018 CU254_RS07675 ec7015b1b9d5a5d4ac47efa3db508507 329 SUPERFAMILY SSF55347 121 282 2.94E-26 T 28-03-2018 CU254_RS02045 ac16121e99e72c2d8df28e62595dc25e 148 Gene3D G3DSA:3.100.10.10 37 148 3.1E-30 T 28-03-2018 CU254_RS02045 ac16121e99e72c2d8df28e62595dc25e 148 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 5 145 4.6E-44 T 28-03-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS02045 ac16121e99e72c2d8df28e62595dc25e 148 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 6 148 19.324 T 28-03-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 CU254_RS02045 ac16121e99e72c2d8df28e62595dc25e 148 SUPERFAMILY SSF52080 9 147 1.11E-38 T 28-03-2018 IPR021131 Ribosomal protein L18e/L15P CU254_RS02045 ac16121e99e72c2d8df28e62595dc25e 148 ProSitePatterns PS00475 Ribosomal protein L15 signature. 111 142 - T 28-03-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS02045 ac16121e99e72c2d8df28e62595dc25e 148 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 29 146 6.8E-32 T 28-03-2018 IPR021131 Ribosomal protein L18e/L15P CU254_RS39550 4500e989cd50703b310bbba5511cea43 519 SUPERFAMILY SSF53756 76 331 6.28E-8 T 28-03-2018 CU254_RS11855 26c29b73f3fffe15a43fbe7c7812ae56 241 Pfam PF08241 Methyltransferase domain 50 143 1.6E-23 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CU254_RS11855 26c29b73f3fffe15a43fbe7c7812ae56 241 SUPERFAMILY SSF53335 4 213 3.84E-41 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS11855 26c29b73f3fffe15a43fbe7c7812ae56 241 Gene3D G3DSA:3.40.50.150 27 236 3.3E-37 T 28-03-2018 CU254_RS21700 9898e70f76a9ceccc13fb748469d5ced 246 Gene3D G3DSA:3.40.50.10090 2 44 1.6E-8 T 28-03-2018 CU254_RS21700 9898e70f76a9ceccc13fb748469d5ced 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 2.0E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS21700 9898e70f76a9ceccc13fb748469d5ced 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 2.0E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS21700 9898e70f76a9ceccc13fb748469d5ced 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 2.0E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS21700 9898e70f76a9ceccc13fb748469d5ced 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 2.0E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS21700 9898e70f76a9ceccc13fb748469d5ced 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 2.0E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS21700 9898e70f76a9ceccc13fb748469d5ced 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 2.0E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS21700 9898e70f76a9ceccc13fb748469d5ced 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 1.8E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS21700 9898e70f76a9ceccc13fb748469d5ced 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 1.8E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS21700 9898e70f76a9ceccc13fb748469d5ced 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 1.8E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS21700 9898e70f76a9ceccc13fb748469d5ced 246 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS21700 9898e70f76a9ceccc13fb748469d5ced 246 SUPERFAMILY SSF51735 6 245 9.34E-79 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS21700 9898e70f76a9ceccc13fb748469d5ced 246 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 190 9.3E-8 T 28-03-2018 CU254_RS21700 9898e70f76a9ceccc13fb748469d5ced 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 244 3.5E-64 T 28-03-2018 CU254_RS21700 9898e70f76a9ceccc13fb748469d5ced 246 Gene3D G3DSA:3.40.50.720 45 246 1.1E-63 T 28-03-2018 CU254_RS31370 0569b798d7ac07d601b7793e0ce97fe0 517 Pfam PF00089 Trypsin 29 254 2.3E-26 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CU254_RS31370 0569b798d7ac07d601b7793e0ce97fe0 517 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 205 217 2.1E-5 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CU254_RS31370 0569b798d7ac07d601b7793e0ce97fe0 517 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 116 130 2.1E-5 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CU254_RS31370 0569b798d7ac07d601b7793e0ce97fe0 517 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 56 71 2.1E-5 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CU254_RS31370 0569b798d7ac07d601b7793e0ce97fe0 517 SMART SM00020 26 254 5.8E-24 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CU254_RS31370 0569b798d7ac07d601b7793e0ce97fe0 517 SUPERFAMILY SSF50494 277 458 5.39E-8 T 28-03-2018 IPR009003 Peptidase S1, PA clan CU254_RS31370 0569b798d7ac07d601b7793e0ce97fe0 517 Gene3D G3DSA:2.40.10.10 27 64 8.2E-10 T 28-03-2018 CU254_RS31370 0569b798d7ac07d601b7793e0ce97fe0 517 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 66 71 - T 28-03-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 CU254_RS31370 0569b798d7ac07d601b7793e0ce97fe0 517 SUPERFAMILY SSF50494 9 259 4.08E-38 T 28-03-2018 IPR009003 Peptidase S1, PA clan CU254_RS31370 0569b798d7ac07d601b7793e0ce97fe0 517 Gene3D G3DSA:2.40.10.10 269 361 0.012 T 28-03-2018 CU254_RS31370 0569b798d7ac07d601b7793e0ce97fe0 517 Gene3D G3DSA:2.40.10.10 65 268 1.8E-31 T 28-03-2018 CU254_RS31370 0569b798d7ac07d601b7793e0ce97fe0 517 Gene3D G3DSA:2.40.10.10 362 472 3.7E-4 T 28-03-2018 CU254_RS32800 de3740c000c9a6d035fe2bd359ef0ddf 334 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 1 308 2.0E-114 T 28-03-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CU254_RS32800 de3740c000c9a6d035fe2bd359ef0ddf 334 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 1 304 2.2E-142 T 28-03-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CU254_RS32800 de3740c000c9a6d035fe2bd359ef0ddf 334 PIRSF PIRSF004532 1 315 1.1E-148 T 28-03-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CU254_RS32800 de3740c000c9a6d035fe2bd359ef0ddf 334 Gene3D G3DSA:3.30.540.10 151 316 2.3E-58 T 28-03-2018 CU254_RS32800 de3740c000c9a6d035fe2bd359ef0ddf 334 Gene3D G3DSA:3.30.540.10 1 150 8.6E-51 T 28-03-2018 CU254_RS32800 de3740c000c9a6d035fe2bd359ef0ddf 334 SUPERFAMILY SSF56655 1 307 9.16E-111 T 28-03-2018 CU254_RS31825 9006dd9c5a8290f43c816b69dec3d89b 336 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 195 208 7.6E-34 T 28-03-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 CU254_RS31825 9006dd9c5a8290f43c816b69dec3d89b 336 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 210 221 7.6E-34 T 28-03-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 CU254_RS31825 9006dd9c5a8290f43c816b69dec3d89b 336 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 262 268 7.6E-34 T 28-03-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 CU254_RS31825 9006dd9c5a8290f43c816b69dec3d89b 336 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 109 127 7.6E-34 T 28-03-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 CU254_RS31825 9006dd9c5a8290f43c816b69dec3d89b 336 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 93 107 7.6E-34 T 28-03-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 CU254_RS31825 9006dd9c5a8290f43c816b69dec3d89b 336 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 48 61 7.6E-34 T 28-03-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 CU254_RS31825 9006dd9c5a8290f43c816b69dec3d89b 336 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 177 190 7.6E-34 T 28-03-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 CU254_RS31825 9006dd9c5a8290f43c816b69dec3d89b 336 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 62 74 7.6E-34 T 28-03-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 CU254_RS31825 9006dd9c5a8290f43c816b69dec3d89b 336 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 57 254 1.5E-18 T 28-03-2018 IPR000477 Reverse transcriptase domain CU254_RS31825 9006dd9c5a8290f43c816b69dec3d89b 336 Gene3D G3DSA:3.30.70.270 73 264 1.7E-13 T 28-03-2018 CU254_RS25720 5f0e06bdb3a1f8c9df5c27345bfe22dc 321 Pfam PF13404 AsnC-type helix-turn-helix domain 5 41 2.1E-9 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS25720 5f0e06bdb3a1f8c9df5c27345bfe22dc 321 Pfam PF13404 AsnC-type helix-turn-helix domain 178 214 5.5E-10 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS25720 5f0e06bdb3a1f8c9df5c27345bfe22dc 321 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 173 189 4.8E-6 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS25720 5f0e06bdb3a1f8c9df5c27345bfe22dc 321 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 200 219 4.8E-6 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS25720 5f0e06bdb3a1f8c9df5c27345bfe22dc 321 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 189 200 4.8E-6 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS25720 5f0e06bdb3a1f8c9df5c27345bfe22dc 321 Gene3D G3DSA:3.30.70.920 56 143 4.0E-4 T 28-03-2018 CU254_RS25720 5f0e06bdb3a1f8c9df5c27345bfe22dc 321 SUPERFAMILY SSF54909 232 313 8.58E-11 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS25720 5f0e06bdb3a1f8c9df5c27345bfe22dc 321 Pfam PF01037 Lrp/AsnC ligand binding domain 239 307 2.5E-9 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CU254_RS25720 5f0e06bdb3a1f8c9df5c27345bfe22dc 321 SUPERFAMILY SSF46785 177 223 1.62E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS25720 5f0e06bdb3a1f8c9df5c27345bfe22dc 321 SUPERFAMILY SSF46785 4 52 2.57E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS25720 5f0e06bdb3a1f8c9df5c27345bfe22dc 321 Gene3D G3DSA:1.10.10.10 1 55 2.4E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS25720 5f0e06bdb3a1f8c9df5c27345bfe22dc 321 Gene3D G3DSA:1.10.10.10 160 222 5.5E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS25720 5f0e06bdb3a1f8c9df5c27345bfe22dc 321 Gene3D G3DSA:3.30.70.920 223 315 3.1E-17 T 28-03-2018 CU254_RS25720 5f0e06bdb3a1f8c9df5c27345bfe22dc 321 SMART SM00344 5 105 8.3E-4 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CU254_RS25720 5f0e06bdb3a1f8c9df5c27345bfe22dc 321 SMART SM00344 178 278 2.5E-14 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CU254_RS26755 763178c140a62dc24e03030c927ec9f5 204 Gene3D G3DSA:3.40.50.1240 2 203 7.7E-53 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CU254_RS26755 763178c140a62dc24e03030c927ec9f5 204 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 8 17 - T 28-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 CU254_RS26755 763178c140a62dc24e03030c927ec9f5 204 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 6 199 6.0E-53 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CU254_RS26755 763178c140a62dc24e03030c927ec9f5 204 PIRSF PIRSF000709 1 180 5.6E-12 T 28-03-2018 CU254_RS26755 763178c140a62dc24e03030c927ec9f5 204 SMART SM00855 5 160 9.1E-19 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CU254_RS26755 763178c140a62dc24e03030c927ec9f5 204 SUPERFAMILY SSF53254 3 199 2.2E-57 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CU254_RS03200 7c01e2efd7d47f4c0c73354adf73065a 407 Pfam PF07730 Histidine kinase 207 271 9.8E-16 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CU254_RS03200 7c01e2efd7d47f4c0c73354adf73065a 407 PRINTS PR00344 Bacterial sensor protein C-terminal signature 346 360 1.2E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS03200 7c01e2efd7d47f4c0c73354adf73065a 407 PRINTS PR00344 Bacterial sensor protein C-terminal signature 364 382 1.2E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS03200 7c01e2efd7d47f4c0c73354adf73065a 407 PRINTS PR00344 Bacterial sensor protein C-terminal signature 388 401 1.2E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS03200 7c01e2efd7d47f4c0c73354adf73065a 407 PIRSF PIRSF037434 11 406 2.2E-67 T 28-03-2018 IPR017205 Signal transduction histidine kinase, ChrS CU254_RS03200 7c01e2efd7d47f4c0c73354adf73065a 407 Gene3D G3DSA:3.30.565.10 164 403 1.4E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS03200 7c01e2efd7d47f4c0c73354adf73065a 407 SUPERFAMILY SSF55874 267 401 1.57E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS03200 7c01e2efd7d47f4c0c73354adf73065a 407 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 312 399 1.0E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS03200 7c01e2efd7d47f4c0c73354adf73065a 407 SMART SM00387 310 404 1.2E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS37150 d2c3cd886153b57d2a6c990b8257bc5a 250 Pfam PF00072 Response regulator receiver domain 26 134 7.0E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS37150 d2c3cd886153b57d2a6c990b8257bc5a 250 Pfam PF00486 Transcriptional regulatory protein, C terminal 173 245 1.2E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS37150 d2c3cd886153b57d2a6c990b8257bc5a 250 SMART SM00448 24 135 2.3E-40 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS37150 d2c3cd886153b57d2a6c990b8257bc5a 250 Gene3D G3DSA:1.10.10.10 159 250 4.7E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS37150 d2c3cd886153b57d2a6c990b8257bc5a 250 Gene3D G3DSA:3.40.50.2300 15 158 8.7E-39 T 28-03-2018 CU254_RS37150 d2c3cd886153b57d2a6c990b8257bc5a 250 SUPERFAMILY SSF52172 22 201 1.85E-40 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS37150 d2c3cd886153b57d2a6c990b8257bc5a 250 SMART SM00862 171 245 1.0E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS08165 5c5f0b4ad7a830fe7cb12ea6fd5ad396 306 SUPERFAMILY SSF53850 94 300 6.52E-28 T 28-03-2018 CU254_RS08165 5c5f0b4ad7a830fe7cb12ea6fd5ad396 306 Gene3D G3DSA:1.10.10.10 1 95 6.2E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS08165 5c5f0b4ad7a830fe7cb12ea6fd5ad396 306 Gene3D G3DSA:3.40.190.10 189 274 9.2E-16 T 28-03-2018 CU254_RS08165 5c5f0b4ad7a830fe7cb12ea6fd5ad396 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 48 59 5.4E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS08165 5c5f0b4ad7a830fe7cb12ea6fd5ad396 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 38 48 5.4E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS08165 5c5f0b4ad7a830fe7cb12ea6fd5ad396 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 27 38 5.4E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS08165 5c5f0b4ad7a830fe7cb12ea6fd5ad396 306 SUPERFAMILY SSF46785 9 89 1.3E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS08165 5c5f0b4ad7a830fe7cb12ea6fd5ad396 306 Pfam PF03466 LysR substrate binding domain 118 301 4.3E-11 T 28-03-2018 IPR005119 LysR, substrate-binding CU254_RS08165 5c5f0b4ad7a830fe7cb12ea6fd5ad396 306 Gene3D G3DSA:3.40.190.10 102 188 1.5E-4 T 28-03-2018 CU254_RS08165 5c5f0b4ad7a830fe7cb12ea6fd5ad396 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 13 71 7.7E-13 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS39400 ee8b410b1f8e5c69be8e60ddd8182254 174 PIRSF PIRSF001467 2 174 7.0E-56 T 28-03-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 CU254_RS39400 ee8b410b1f8e5c69be8e60ddd8182254 174 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 57 74 - T 28-03-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 CU254_RS39400 ee8b410b1f8e5c69be8e60ddd8182254 174 SUPERFAMILY SSF50891 7 172 5.55E-61 T 28-03-2018 IPR029000 Cyclophilin-like domain CU254_RS39400 ee8b410b1f8e5c69be8e60ddd8182254 174 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 9 171 1.4E-44 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CU254_RS39400 ee8b410b1f8e5c69be8e60ddd8182254 174 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 102 117 2.5E-24 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CU254_RS39400 ee8b410b1f8e5c69be8e60ddd8182254 174 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 21 36 2.5E-24 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CU254_RS39400 ee8b410b1f8e5c69be8e60ddd8182254 174 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 62 74 2.5E-24 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CU254_RS39400 ee8b410b1f8e5c69be8e60ddd8182254 174 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 130 145 2.5E-24 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CU254_RS39400 ee8b410b1f8e5c69be8e60ddd8182254 174 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 117 129 2.5E-24 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CU254_RS39400 ee8b410b1f8e5c69be8e60ddd8182254 174 Gene3D G3DSA:2.40.100.10 1 174 3.4E-62 T 28-03-2018 IPR029000 Cyclophilin-like domain CU254_RS00055 a8fba33731be60e6096e36ea03b36b45 182 SUPERFAMILY SSF46785 3 175 1.43E-40 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS00055 a8fba33731be60e6096e36ea03b36b45 182 Pfam PF10400 Virulence activator alpha C-term 94 175 1.2E-23 T 28-03-2018 IPR018309 Transcription regulator PadR, C-terminal CU254_RS00055 a8fba33731be60e6096e36ea03b36b45 182 Gene3D G3DSA:1.10.10.10 1 91 5.8E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS00055 a8fba33731be60e6096e36ea03b36b45 182 Pfam PF03551 Transcriptional regulator PadR-like family 7 80 5.3E-13 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CU254_RS21760 ffd816a8b404d66501dec111371f3ab3 400 PRINTS PR00359 B-class P450 signature 138 154 7.3E-46 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS21760 ffd816a8b404d66501dec111371f3ab3 400 PRINTS PR00359 B-class P450 signature 339 348 7.3E-46 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS21760 ffd816a8b404d66501dec111371f3ab3 400 PRINTS PR00359 B-class P450 signature 290 317 7.3E-46 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS21760 ffd816a8b404d66501dec111371f3ab3 400 PRINTS PR00359 B-class P450 signature 348 359 7.3E-46 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS21760 ffd816a8b404d66501dec111371f3ab3 400 PRINTS PR00359 B-class P450 signature 190 212 7.3E-46 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS21760 ffd816a8b404d66501dec111371f3ab3 400 PRINTS PR00359 B-class P450 signature 318 333 7.3E-46 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS21760 ffd816a8b404d66501dec111371f3ab3 400 PRINTS PR00359 B-class P450 signature 272 283 7.3E-46 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS21760 ffd816a8b404d66501dec111371f3ab3 400 PRINTS PR00359 B-class P450 signature 92 103 7.3E-46 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS21760 ffd816a8b404d66501dec111371f3ab3 400 PRINTS PR00359 B-class P450 signature 155 170 7.3E-46 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS21760 ffd816a8b404d66501dec111371f3ab3 400 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 341 350 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CU254_RS21760 ffd816a8b404d66501dec111371f3ab3 400 Pfam PF00067 Cytochrome P450 171 369 2.1E-23 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS21760 ffd816a8b404d66501dec111371f3ab3 400 SUPERFAMILY SSF48264 3 399 8.25E-99 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS21760 ffd816a8b404d66501dec111371f3ab3 400 Gene3D G3DSA:1.10.630.10 4 400 2.6E-81 T 28-03-2018 CU254_RS21550 41b937ae8823e00749cad79986457e22 349 Gene3D G3DSA:3.20.20.30 1 344 1.5E-72 T 28-03-2018 CU254_RS21550 41b937ae8823e00749cad79986457e22 349 Pfam PF00296 Luciferase-like monooxygenase 18 317 1.7E-82 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS21550 41b937ae8823e00749cad79986457e22 349 TIGRFAM TIGR03559 F420_Rv3520c: probable F420-dependent oxidoreductase, Rv3520c family 2 321 6.3E-114 T 28-03-2018 IPR019951 F420-dependent oxidoreductase-predicted, Rv3520c CU254_RS21550 41b937ae8823e00749cad79986457e22 349 SUPERFAMILY SSF51679 1 340 3.79E-74 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS27070 ea39b0a6f07ac219a79693380af2a86b 233 SMART SM00332 2 216 0.0035 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CU254_RS27070 ea39b0a6f07ac219a79693380af2a86b 233 Gene3D G3DSA:3.60.40.10 7 217 4.5E-22 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CU254_RS27070 ea39b0a6f07ac219a79693380af2a86b 233 SUPERFAMILY SSF81606 6 216 8.5E-26 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CU254_RS07425 943ef0d17cf6db4253925f3705d2d75e 606 SUPERFAMILY SSF53955 62 252 7.03E-49 T 28-03-2018 IPR023346 Lysozyme-like domain CU254_RS07425 943ef0d17cf6db4253925f3705d2d75e 606 Pfam PF00912 Transglycosylase 79 241 1.3E-45 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CU254_RS07425 943ef0d17cf6db4253925f3705d2d75e 606 Gene3D G3DSA:1.10.3810.10 61 255 1.4E-52 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CU254_RS07425 943ef0d17cf6db4253925f3705d2d75e 606 Gene3D G3DSA:3.40.710.10 264 606 6.4E-63 T 28-03-2018 CU254_RS07425 943ef0d17cf6db4253925f3705d2d75e 606 SUPERFAMILY SSF56601 228 245 5.4E-61 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CU254_RS07425 943ef0d17cf6db4253925f3705d2d75e 606 SUPERFAMILY SSF56601 275 605 5.4E-61 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CU254_RS07425 943ef0d17cf6db4253925f3705d2d75e 606 Pfam PF00905 Penicillin binding protein transpeptidase domain 331 571 3.2E-19 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CU254_RS27935 3400940141efaa2da77beef2caadb458 271 Pfam PF00561 alpha/beta hydrolase fold 24 251 1.2E-22 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS27935 3400940141efaa2da77beef2caadb458 271 Gene3D G3DSA:3.40.50.1820 1 267 8.6E-59 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS27935 3400940141efaa2da77beef2caadb458 271 PRINTS PR00412 Epoxide hydrolase signature 106 119 5.9E-10 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS27935 3400940141efaa2da77beef2caadb458 271 PRINTS PR00412 Epoxide hydrolase signature 29 47 5.9E-10 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS27935 3400940141efaa2da77beef2caadb458 271 PRINTS PR00412 Epoxide hydrolase signature 240 262 5.9E-10 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS27935 3400940141efaa2da77beef2caadb458 271 PRINTS PR00412 Epoxide hydrolase signature 49 64 5.9E-10 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS27935 3400940141efaa2da77beef2caadb458 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 106 119 5.0E-13 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS27935 3400940141efaa2da77beef2caadb458 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 209 223 5.0E-13 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS27935 3400940141efaa2da77beef2caadb458 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 92 105 5.0E-13 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS27935 3400940141efaa2da77beef2caadb458 271 PRINTS PR00111 Alpha/beta hydrolase fold signature 49 64 5.0E-13 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS27935 3400940141efaa2da77beef2caadb458 271 SUPERFAMILY SSF53474 4 264 2.55E-66 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS22720 ad8e62889aca2e23e328aac76ca31de5 325 SUPERFAMILY SSF47413 2 59 2.22E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS22720 ad8e62889aca2e23e328aac76ca31de5 325 Gene3D G3DSA:1.10.260.40 2 55 7.8E-24 T 28-03-2018 CU254_RS22720 ad8e62889aca2e23e328aac76ca31de5 325 SUPERFAMILY SSF53822 62 323 3.93E-69 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CU254_RS22720 ad8e62889aca2e23e328aac76ca31de5 325 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 2.4E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CU254_RS22720 ad8e62889aca2e23e328aac76ca31de5 325 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 2.4E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CU254_RS22720 ad8e62889aca2e23e328aac76ca31de5 325 Pfam PF13377 Periplasmic binding protein-like domain 167 323 2.7E-33 T 28-03-2018 CU254_RS22720 ad8e62889aca2e23e328aac76ca31de5 325 SMART SM00354 1 71 9.2E-28 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CU254_RS22720 ad8e62889aca2e23e328aac76ca31de5 325 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 1.5E-18 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CU254_RS22720 ad8e62889aca2e23e328aac76ca31de5 325 Gene3D G3DSA:3.40.50.2300 174 306 4.0E-40 T 28-03-2018 CU254_RS22720 ad8e62889aca2e23e328aac76ca31de5 325 Gene3D G3DSA:3.40.50.2300 56 173 2.3E-38 T 28-03-2018 CU254_RS10080 19022805f18556c53f5f4881f6deb865 255 PIRSF PIRSF017388 1 249 1.8E-64 T 28-03-2018 IPR012354 Esterase/lipase GO:0052689 CU254_RS10080 19022805f18556c53f5f4881f6deb865 255 SUPERFAMILY SSF53474 13 247 5.59E-37 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS10080 19022805f18556c53f5f4881f6deb865 255 Pfam PF12146 Serine aminopeptidase, S33 21 230 1.9E-22 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 CU254_RS10080 19022805f18556c53f5f4881f6deb865 255 Gene3D G3DSA:3.40.50.1820 3 248 2.3E-41 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS29655 46e67adf90af5941a2098d82802679fc 238 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 231 6.9E-50 T 28-03-2018 CU254_RS29655 46e67adf90af5941a2098d82802679fc 238 SUPERFAMILY SSF51735 1 232 2.36E-64 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS29655 46e67adf90af5941a2098d82802679fc 238 Gene3D G3DSA:3.40.50.720 154 229 1.3E-21 T 28-03-2018 CU254_RS29655 46e67adf90af5941a2098d82802679fc 238 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 166 6.9E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS29655 46e67adf90af5941a2098d82802679fc 238 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 6.9E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS29655 46e67adf90af5941a2098d82802679fc 238 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 134 162 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS29655 46e67adf90af5941a2098d82802679fc 238 Gene3D G3DSA:3.40.50.720 4 153 3.6E-43 T 28-03-2018 CU254_RS29655 46e67adf90af5941a2098d82802679fc 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 214 4.3E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS29655 46e67adf90af5941a2098d82802679fc 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 4.3E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS29655 46e67adf90af5941a2098d82802679fc 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 4.3E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS29655 46e67adf90af5941a2098d82802679fc 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 4.3E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS29655 46e67adf90af5941a2098d82802679fc 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 4.3E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS09000 77202cc3129cfbd3890fcab3cd496180 549 SUPERFAMILY SSF51905 360 427 4.96E-56 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS09000 77202cc3129cfbd3890fcab3cd496180 549 SUPERFAMILY SSF51905 18 252 4.96E-56 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS09000 77202cc3129cfbd3890fcab3cd496180 549 SUPERFAMILY SSF46977 437 535 3.66E-20 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CU254_RS09000 77202cc3129cfbd3890fcab3cd496180 549 Gene3D G3DSA:3.50.50.60 4 306 1.5E-51 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS09000 77202cc3129cfbd3890fcab3cd496180 549 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 21 517 2.7E-158 T 28-03-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 CU254_RS09000 77202cc3129cfbd3890fcab3cd496180 549 Pfam PF00890 FAD binding domain 23 401 6.1E-85 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CU254_RS09000 77202cc3129cfbd3890fcab3cd496180 549 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 23 45 2.3E-8 T 28-03-2018 CU254_RS09000 77202cc3129cfbd3890fcab3cd496180 549 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 379 386 2.3E-8 T 28-03-2018 CU254_RS09000 77202cc3129cfbd3890fcab3cd496180 549 Gene3D G3DSA:3.50.50.60 307 420 4.7E-14 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS09000 77202cc3129cfbd3890fcab3cd496180 549 Pfam PF02910 Fumarate reductase flavoprotein C-term 444 521 2.1E-9 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CU254_RS09000 77202cc3129cfbd3890fcab3cd496180 549 Gene3D G3DSA:1.20.58.100 429 534 5.0E-22 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CU254_RS09000 77202cc3129cfbd3890fcab3cd496180 549 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 24 43 6.0E-9 T 28-03-2018 CU254_RS09000 77202cc3129cfbd3890fcab3cd496180 549 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 274 296 6.0E-9 T 28-03-2018 CU254_RS09000 77202cc3129cfbd3890fcab3cd496180 549 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 141 159 6.0E-9 T 28-03-2018 CU254_RS09000 77202cc3129cfbd3890fcab3cd496180 549 SUPERFAMILY SSF56425 244 361 1.5E-30 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CU254_RS24620 e3fe0874dbc151041c185d0673b5d159 639 Gene3D G3DSA:3.90.1310.10 51 273 3.7E-30 T 28-03-2018 CU254_RS24620 e3fe0874dbc151041c185d0673b5d159 639 SUPERFAMILY SSF56601 277 624 5.23E-89 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CU254_RS24620 e3fe0874dbc151041c185d0673b5d159 639 SUPERFAMILY SSF56519 79 276 2.35E-25 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CU254_RS24620 e3fe0874dbc151041c185d0673b5d159 639 Gene3D G3DSA:3.40.710.10 274 623 3.5E-85 T 28-03-2018 CU254_RS24620 e3fe0874dbc151041c185d0673b5d159 639 Pfam PF03717 Penicillin-binding Protein dimerisation domain 82 253 1.4E-13 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CU254_RS24620 e3fe0874dbc151041c185d0673b5d159 639 Pfam PF00905 Penicillin binding protein transpeptidase domain 303 614 3.9E-77 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CU254_RS27525 a216b4b0551aa266d908cbc6b361cc51 150 Pfam PF14279 HNH endonuclease 67 112 1.9E-12 T 28-03-2018 IPR029471 HNH endonuclease 5 CU254_RS27525 a216b4b0551aa266d908cbc6b361cc51 150 SMART SM00507 54 103 2.4E-14 T 28-03-2018 IPR003615 HNH nuclease CU254_RS27525 a216b4b0551aa266d908cbc6b361cc51 150 Gene3D G3DSA:3.40.1800.10 48 118 4.2E-17 T 28-03-2018 CU254_RS23100 618ed91324134af1bc265260fcf12ea7 501 Gene3D G3DSA:3.40.50.980 3 169 1.9E-41 T 28-03-2018 CU254_RS23100 618ed91324134af1bc265260fcf12ea7 501 Gene3D G3DSA:2.30.38.10 321 404 2.4E-29 T 28-03-2018 CU254_RS23100 618ed91324134af1bc265260fcf12ea7 501 Gene3D G3DSA:3.30.300.30 406 501 7.7E-32 T 28-03-2018 CU254_RS23100 618ed91324134af1bc265260fcf12ea7 501 SUPERFAMILY SSF56801 4 501 5.76E-163 T 28-03-2018 CU254_RS23100 618ed91324134af1bc265260fcf12ea7 501 Gene3D G3DSA:3.40.50.980 170 320 1.8E-52 T 28-03-2018 CU254_RS23100 618ed91324134af1bc265260fcf12ea7 501 Pfam PF13193 AMP-binding enzyme C-terminal domain 420 495 1.5E-22 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS23100 618ed91324134af1bc265260fcf12ea7 501 Pfam PF00501 AMP-binding enzyme 11 411 4.2E-110 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS23100 618ed91324134af1bc265260fcf12ea7 501 ProSitePatterns PS00455 Putative AMP-binding domain signature. 164 175 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS27270 900e4be12f8fa4a5e68dcf6913812e06 345 Pfam PF01435 Peptidase family M48 71 266 1.3E-18 T 28-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CU254_RS27270 900e4be12f8fa4a5e68dcf6913812e06 345 Gene3D G3DSA:3.30.2010.10 63 154 1.1E-16 T 28-03-2018 CU254_RS13155 f318d8f1288725d4a5e40876d14bb9f7 353 Pfam PF04679 ATP dependent DNA ligase C terminal region 214 327 8.5E-15 T 28-03-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 CU254_RS13155 f318d8f1288725d4a5e40876d14bb9f7 353 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 24 32 - T 28-03-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 CU254_RS13155 f318d8f1288725d4a5e40876d14bb9f7 353 Gene3D G3DSA:3.30.1490.70 141 195 2.9E-11 T 28-03-2018 CU254_RS13155 f318d8f1288725d4a5e40876d14bb9f7 353 Gene3D G3DSA:3.30.470.30 1 140 2.3E-36 T 28-03-2018 CU254_RS13155 f318d8f1288725d4a5e40876d14bb9f7 353 SUPERFAMILY SSF50249 199 336 1.14E-13 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CU254_RS13155 f318d8f1288725d4a5e40876d14bb9f7 353 Pfam PF01068 ATP dependent DNA ligase domain 6 196 1.4E-39 T 28-03-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 CU254_RS13155 f318d8f1288725d4a5e40876d14bb9f7 353 SUPERFAMILY SSF56091 2 196 7.92E-46 T 28-03-2018 CU254_RS13155 f318d8f1288725d4a5e40876d14bb9f7 353 Gene3D G3DSA:2.40.50.140 196 348 2.7E-32 T 28-03-2018 CU254_RS02390 994675212fc31af1eabbbb63d8630b5b 106 Pfam PF02467 Transcription factor WhiB 23 92 3.4E-22 T 28-03-2018 IPR034768 WhiB-like iron-sulfur binding domain CU254_RS02390 994675212fc31af1eabbbb63d8630b5b 106 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 20 98 18.11 T 28-03-2018 IPR003482 Transcription factor WhiB CU254_RS25405 2f8c1ed48d4bf9bbafadf4efefdaa452 225 Gene3D G3DSA:3.40.225.10 3 225 5.7E-62 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CU254_RS25405 2f8c1ed48d4bf9bbafadf4efefdaa452 225 SUPERFAMILY SSF53639 11 219 1.96E-61 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CU254_RS25405 2f8c1ed48d4bf9bbafadf4efefdaa452 225 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 18 193 1.1E-47 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CU254_RS25405 2f8c1ed48d4bf9bbafadf4efefdaa452 225 SMART SM01007 16 195 1.4E-61 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CU254_RS22205 f0a561820d0c5ac78cde2022e8d8b4d7 641 Pfam PF00465 Iron-containing alcohol dehydrogenase 8 334 2.4E-81 T 28-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 CU254_RS22205 f0a561820d0c5ac78cde2022e8d8b4d7 641 SUPERFAMILY SSF49482 359 635 1.83E-85 T 28-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 CU254_RS22205 f0a561820d0c5ac78cde2022e8d8b4d7 641 Gene3D G3DSA:3.40.50.1970 1 158 6.6E-39 T 28-03-2018 CU254_RS22205 f0a561820d0c5ac78cde2022e8d8b4d7 641 SUPERFAMILY SSF56796 5 348 9.16E-93 T 28-03-2018 CU254_RS22205 f0a561820d0c5ac78cde2022e8d8b4d7 641 Gene3D G3DSA:1.20.1090.10 160 350 5.4E-54 T 28-03-2018 CU254_RS22205 f0a561820d0c5ac78cde2022e8d8b4d7 641 Pfam PF00775 Dioxygenase 454 632 8.1E-46 T 28-03-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 CU254_RS22205 f0a561820d0c5ac78cde2022e8d8b4d7 641 Pfam PF04444 Catechol dioxygenase N terminus 375 445 5.9E-26 T 28-03-2018 IPR007535 Catechol dioxygenase, N-terminal GO:0005506|GO:0009712|GO:0018576|GO:0055114 CU254_RS22205 f0a561820d0c5ac78cde2022e8d8b4d7 641 Gene3D G3DSA:2.60.130.10 356 635 5.6E-81 T 28-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 CU254_RS22590 2388c25b0559c7f40da63c2ee21096cc 528 SUPERFAMILY SSF55785 205 309 1.01E-7 T 28-03-2018 IPR000014 PAS domain CU254_RS22590 2388c25b0559c7f40da63c2ee21096cc 528 Pfam PF17203 Single cache domain 3 36 169 1.8E-30 T 28-03-2018 IPR033463 Single cache domain 3 CU254_RS22590 2388c25b0559c7f40da63c2ee21096cc 528 Gene3D G3DSA:1.10.287.130 324 375 5.2E-14 T 28-03-2018 CU254_RS22590 2388c25b0559c7f40da63c2ee21096cc 528 PRINTS PR00344 Bacterial sensor protein C-terminal signature 457 471 8.1E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS22590 2388c25b0559c7f40da63c2ee21096cc 528 PRINTS PR00344 Bacterial sensor protein C-terminal signature 487 505 8.1E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS22590 2388c25b0559c7f40da63c2ee21096cc 528 Gene3D G3DSA:3.30.450.20 32 163 1.0E-25 T 28-03-2018 CU254_RS22590 2388c25b0559c7f40da63c2ee21096cc 528 SUPERFAMILY SSF55874 391 523 1.7E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS22590 2388c25b0559c7f40da63c2ee21096cc 528 SMART SM00091 212 278 4.7E-5 T 28-03-2018 IPR000014 PAS domain CU254_RS22590 2388c25b0559c7f40da63c2ee21096cc 528 Pfam PF13188 PAS domain 212 258 1.5E-7 T 28-03-2018 IPR000014 PAS domain CU254_RS22590 2388c25b0559c7f40da63c2ee21096cc 528 SUPERFAMILY SSF103190 38 168 4.71E-32 T 28-03-2018 IPR029151 Periplasmic sensor domain-like CU254_RS22590 2388c25b0559c7f40da63c2ee21096cc 528 Gene3D G3DSA:3.30.450.20 197 323 5.1E-13 T 28-03-2018 CU254_RS22590 2388c25b0559c7f40da63c2ee21096cc 528 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 419 523 2.8E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS22590 2388c25b0559c7f40da63c2ee21096cc 528 Gene3D G3DSA:3.30.565.10 376 528 6.2E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS22590 2388c25b0559c7f40da63c2ee21096cc 528 SMART SM00387 416 525 2.0E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS37805 12edd70ca135e8d9c02bf2c0706ec4e5 204 Pfam PF01081 KDPG and KHG aldolase 15 188 7.4E-39 T 28-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 CU254_RS37805 12edd70ca135e8d9c02bf2c0706ec4e5 204 Gene3D G3DSA:3.20.20.70 5 204 3.4E-38 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS37805 12edd70ca135e8d9c02bf2c0706ec4e5 204 SUPERFAMILY SSF51569 5 193 5.86E-56 T 28-03-2018 CU254_RS37805 12edd70ca135e8d9c02bf2c0706ec4e5 204 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 13 189 3.6E-49 T 28-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 CU254_RS28770 be45bae7e6e5ef28c8ff1c01e8ab2d20 232 Gene3D G3DSA:2.40.260.10 58 231 9.5E-42 T 28-03-2018 IPR023365 Sortase domain CU254_RS28770 be45bae7e6e5ef28c8ff1c01e8ab2d20 232 SUPERFAMILY SSF63817 90 224 1.44E-30 T 28-03-2018 IPR023365 Sortase domain CU254_RS28770 be45bae7e6e5ef28c8ff1c01e8ab2d20 232 Pfam PF04203 Sortase family 96 223 5.0E-29 T 28-03-2018 IPR005754 Sortase family CU254_RS28770 be45bae7e6e5ef28c8ff1c01e8ab2d20 232 TIGRFAM TIGR01076 sortase_fam: sortase 95 227 1.1E-16 T 28-03-2018 IPR005754 Sortase family CU254_RS02920 9f657cde07f0638ae45d5a11f367d63d 360 Gene3D G3DSA:3.40.50.300 3 244 1.0E-68 T 28-03-2018 CU254_RS02920 9f657cde07f0638ae45d5a11f367d63d 360 Pfam PF08402 TOBE domain 281 343 3.1E-7 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CU254_RS02920 9f657cde07f0638ae45d5a11f367d63d 360 SMART SM00382 32 215 6.4E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS02920 9f657cde07f0638ae45d5a11f367d63d 360 SUPERFAMILY SSF52540 11 246 4.84E-82 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS02920 9f657cde07f0638ae45d5a11f367d63d 360 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS02920 9f657cde07f0638ae45d5a11f367d63d 360 SUPERFAMILY SSF50331 240 359 1.51E-23 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CU254_RS02920 9f657cde07f0638ae45d5a11f367d63d 360 Gene3D G3DSA:2.40.50.140 285 343 3.9E-19 T 28-03-2018 CU254_RS02920 9f657cde07f0638ae45d5a11f367d63d 360 Gene3D G3DSA:2.40.50.100 245 284 1.0E-9 T 28-03-2018 CU254_RS02920 9f657cde07f0638ae45d5a11f367d63d 360 Pfam PF00005 ABC transporter 24 165 1.1E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS15005 2e179d174c3a72f00ce24a1e2cc5bed8 258 SUPERFAMILY SSF53335 14 239 1.21E-43 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS15005 2e179d174c3a72f00ce24a1e2cc5bed8 258 Gene3D G3DSA:3.40.50.150 10 240 1.7E-37 T 28-03-2018 CU254_RS15005 2e179d174c3a72f00ce24a1e2cc5bed8 258 Pfam PF08241 Methyltransferase domain 43 139 4.1E-22 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CU254_RS21370 4bb25eb72b0aff7df16bd28e8c758bdd 634 SMART SM00382 415 601 5.7E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS21370 4bb25eb72b0aff7df16bd28e8c758bdd 634 Pfam PF00664 ABC transporter transmembrane region 36 344 6.4E-59 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CU254_RS21370 4bb25eb72b0aff7df16bd28e8c758bdd 634 Pfam PF00005 ABC transporter 407 555 2.0E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS21370 4bb25eb72b0aff7df16bd28e8c758bdd 634 Gene3D G3DSA:1.20.1560.10 3 375 4.2E-84 T 28-03-2018 CU254_RS21370 4bb25eb72b0aff7df16bd28e8c758bdd 634 SUPERFAMILY SSF90123 20 58 6.28E-80 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CU254_RS21370 4bb25eb72b0aff7df16bd28e8c758bdd 634 SUPERFAMILY SSF90123 98 377 6.28E-80 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CU254_RS21370 4bb25eb72b0aff7df16bd28e8c758bdd 634 SUPERFAMILY SSF52540 381 626 1.54E-87 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS21370 4bb25eb72b0aff7df16bd28e8c758bdd 634 Gene3D G3DSA:3.40.50.300 376 631 1.9E-74 T 28-03-2018 CU254_RS21370 4bb25eb72b0aff7df16bd28e8c758bdd 634 ProSitePatterns PS00211 ABC transporters family signature. 527 541 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS39745 da00f7ad65dadfbf3731d3b042b5bbb2 178 Pfam PF04234 CopC domain 16 109 2.7E-24 T 28-03-2018 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 CU254_RS39745 da00f7ad65dadfbf3731d3b042b5bbb2 178 SUPERFAMILY SSF81296 15 110 7.0E-22 T 28-03-2018 IPR014756 Immunoglobulin E-set CU254_RS39745 da00f7ad65dadfbf3731d3b042b5bbb2 178 Gene3D G3DSA:2.60.40.1220 15 111 3.5E-25 T 28-03-2018 CU254_RS33330 23f53ec2f5fb5c63d0a2bec6d439494c 399 SMART SM00387 309 399 1.2E-4 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS33330 23f53ec2f5fb5c63d0a2bec6d439494c 399 Pfam PF13796 Putative sensor 14 180 2.6E-22 T 28-03-2018 IPR025828 Putative sensor domain CU254_RS33330 23f53ec2f5fb5c63d0a2bec6d439494c 399 SUPERFAMILY SSF55874 289 396 1.35E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS33330 23f53ec2f5fb5c63d0a2bec6d439494c 399 Gene3D G3DSA:3.30.565.10 189 398 6.7E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS33330 23f53ec2f5fb5c63d0a2bec6d439494c 399 Pfam PF07730 Histidine kinase 209 276 5.1E-14 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CU254_RS25890 43778044cdeec36c17507421b6521dff 439 SMART SM00267 240 419 5.5E-47 T 28-03-2018 IPR000160 GGDEF domain CU254_RS25890 43778044cdeec36c17507421b6521dff 439 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 250 418 1.1E-43 T 28-03-2018 IPR000160 GGDEF domain CU254_RS25890 43778044cdeec36c17507421b6521dff 439 Pfam PF00990 Diguanylate cyclase, GGDEF domain 252 415 1.0E-39 T 28-03-2018 IPR000160 GGDEF domain CU254_RS25890 43778044cdeec36c17507421b6521dff 439 SUPERFAMILY SSF55073 257 418 2.04E-42 T 28-03-2018 IPR029787 Nucleotide cyclase CU254_RS25890 43778044cdeec36c17507421b6521dff 439 Gene3D G3DSA:3.30.70.270 245 424 6.2E-51 T 28-03-2018 CU254_RS20065 89c7e8d7719ee4e4957cee6cd3ae6647 690 Pfam PF00069 Protein kinase domain 16 183 7.2E-34 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CU254_RS20065 89c7e8d7719ee4e4957cee6cd3ae6647 690 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 96 108 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CU254_RS20065 89c7e8d7719ee4e4957cee6cd3ae6647 690 SMART SM00220 1 212 1.7E-18 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CU254_RS20065 89c7e8d7719ee4e4957cee6cd3ae6647 690 Gene3D G3DSA:3.30.200.20 1 62 1.3E-8 T 28-03-2018 CU254_RS20065 89c7e8d7719ee4e4957cee6cd3ae6647 690 Gene3D G3DSA:1.10.510.10 63 456 3.9E-39 T 28-03-2018 CU254_RS20065 89c7e8d7719ee4e4957cee6cd3ae6647 690 SUPERFAMILY SSF56112 1 218 4.05E-53 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS19455 338c37a88168b51038a8fbeb6908256c 643 SUPERFAMILY SSF53474 370 629 5.41E-56 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS19455 338c37a88168b51038a8fbeb6908256c 643 Pfam PF00326 Prolyl oligopeptidase family 421 630 4.7E-41 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CU254_RS19455 338c37a88168b51038a8fbeb6908256c 643 Gene3D G3DSA:3.40.50.1820 345 636 5.5E-45 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS19455 338c37a88168b51038a8fbeb6908256c 643 Gene3D G3DSA:2.140.10.30 6 204 2.2E-11 T 28-03-2018 CU254_RS19455 338c37a88168b51038a8fbeb6908256c 643 SUPERFAMILY SSF69304 290 355 1.19E-12 T 28-03-2018 CU254_RS19455 338c37a88168b51038a8fbeb6908256c 643 SUPERFAMILY SSF69304 86 198 1.19E-12 T 28-03-2018 CU254_RS34325 96c57db6182960814fe5c88e91e83356 317 Gene3D G3DSA:1.10.10.10 1 55 7.0E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS34325 96c57db6182960814fe5c88e91e83356 317 Gene3D G3DSA:3.30.70.920 58 151 0.016 T 28-03-2018 CU254_RS34325 96c57db6182960814fe5c88e91e83356 317 Gene3D G3DSA:3.30.70.920 223 317 1.9E-16 T 28-03-2018 CU254_RS34325 96c57db6182960814fe5c88e91e83356 317 Gene3D G3DSA:1.10.10.10 163 218 7.9E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS34325 96c57db6182960814fe5c88e91e83356 317 SUPERFAMILY SSF46785 171 230 1.53E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS34325 96c57db6182960814fe5c88e91e83356 317 SUPERFAMILY SSF46785 5 59 1.14E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS34325 96c57db6182960814fe5c88e91e83356 317 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 198 217 1.3E-10 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS34325 96c57db6182960814fe5c88e91e83356 317 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 187 198 1.3E-10 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS34325 96c57db6182960814fe5c88e91e83356 317 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 171 187 1.3E-10 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS34325 96c57db6182960814fe5c88e91e83356 317 SUPERFAMILY SSF54909 234 309 2.55E-12 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS34325 96c57db6182960814fe5c88e91e83356 317 SMART SM00344 6 110 1.4E-4 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CU254_RS34325 96c57db6182960814fe5c88e91e83356 317 SMART SM00344 171 276 3.0E-15 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CU254_RS34325 96c57db6182960814fe5c88e91e83356 317 Pfam PF01037 Lrp/AsnC ligand binding domain 238 306 7.8E-12 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CU254_RS34325 96c57db6182960814fe5c88e91e83356 317 Pfam PF13404 AsnC-type helix-turn-helix domain 6 47 1.7E-13 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS34325 96c57db6182960814fe5c88e91e83356 317 Pfam PF13404 AsnC-type helix-turn-helix domain 172 212 1.4E-11 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS21380 b0656309e7ebb73ada636a78329cfa6c 248 SUPERFAMILY SSF55961 4 134 8.68E-22 T 28-03-2018 CU254_RS21380 b0656309e7ebb73ada636a78329cfa6c 248 Gene3D G3DSA:3.30.530.20 1 161 7.0E-22 T 28-03-2018 IPR023393 START-like domain CU254_RS21380 b0656309e7ebb73ada636a78329cfa6c 248 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 15 133 1.9E-10 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CU254_RS17010 229c0723144c678328b9e77313b664a4 392 SUPERFAMILY SSF53474 4 387 2.37E-92 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS17010 229c0723144c678328b9e77313b664a4 392 PIRSF PIRSF001112 2 391 4.8E-114 T 28-03-2018 IPR016292 Epoxide hydrolase GO:0033961 KEGG: 00980+3.3.2.9|Reactome: R-HSA-211945 CU254_RS17010 229c0723144c678328b9e77313b664a4 392 Gene3D G3DSA:3.40.50.1820 2 391 4.7E-74 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS17010 229c0723144c678328b9e77313b664a4 392 PRINTS PR00412 Epoxide hydrolase signature 105 123 6.8E-16 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS17010 229c0723144c678328b9e77313b664a4 392 PRINTS PR00412 Epoxide hydrolase signature 363 385 6.8E-16 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS17010 229c0723144c678328b9e77313b664a4 392 PRINTS PR00412 Epoxide hydrolase signature 193 206 6.8E-16 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS17010 229c0723144c678328b9e77313b664a4 392 PRINTS PR00412 Epoxide hydrolase signature 134 149 6.8E-16 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS17010 229c0723144c678328b9e77313b664a4 392 PRINTS PR00412 Epoxide hydrolase signature 179 192 6.8E-16 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS17010 229c0723144c678328b9e77313b664a4 392 Pfam PF06441 Epoxide hydrolase N terminus 11 114 5.6E-29 T 28-03-2018 IPR010497 Epoxide hydrolase, N-terminal KEGG: 00980+3.3.2.9|Reactome: R-HSA-211945 CU254_RS32440 511124996fce745d0e14ddf5d1316a08 227 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 102 1.9E-28 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CU254_RS32440 511124996fce745d0e14ddf5d1316a08 227 Gene3D G3DSA:3.30.160.100 1 105 2.4E-25 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CU254_RS32440 511124996fce745d0e14ddf5d1316a08 227 Hamap MF_00839 Ribosome hibernation promoting factor [hpf]. 1 227 23.068 T 28-03-2018 IPR034694 Ribosome hibernation promoting factor, long/plastid CU254_RS32440 511124996fce745d0e14ddf5d1316a08 227 SUPERFAMILY SSF69754 1 106 6.02E-24 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CU254_RS32440 511124996fce745d0e14ddf5d1316a08 227 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 99 8.0E-20 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CU254_RS32440 511124996fce745d0e14ddf5d1316a08 227 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 169 223 3.7E-22 T 28-03-2018 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal CU254_RS19755 f1e408f0e4d62116f8a9cb51622af512 157 SUPERFAMILY SSF55961 4 153 1.55E-20 T 28-03-2018 CU254_RS19755 f1e408f0e4d62116f8a9cb51622af512 157 Gene3D G3DSA:3.30.530.20 1 156 1.9E-22 T 28-03-2018 IPR023393 START-like domain CU254_RS19755 f1e408f0e4d62116f8a9cb51622af512 157 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 4 149 7.7E-9 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase CU254_RS37215 97e24a05eba7ac9aa9a18e1a83423a33 249 SMART SM00332 3 244 8.7E-16 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CU254_RS37215 97e24a05eba7ac9aa9a18e1a83423a33 249 SMART SM00331 16 246 3.3E-25 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CU254_RS37215 97e24a05eba7ac9aa9a18e1a83423a33 249 Pfam PF13672 Protein phosphatase 2C 20 209 4.4E-14 T 28-03-2018 CU254_RS37215 97e24a05eba7ac9aa9a18e1a83423a33 249 SUPERFAMILY SSF81606 9 245 1.07E-57 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CU254_RS37215 97e24a05eba7ac9aa9a18e1a83423a33 249 Gene3D G3DSA:3.60.40.10 10 246 2.4E-38 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CU254_RS21395 723dd090c060c906db0bbe2e2678325a 325 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 270 312 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CU254_RS21395 723dd090c060c906db0bbe2e2678325a 325 SUPERFAMILY SSF52317 6 198 2.08E-47 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS21395 723dd090c060c906db0bbe2e2678325a 325 Gene3D G3DSA:1.10.10.60 226 270 6.0E-10 T 28-03-2018 CU254_RS21395 723dd090c060c906db0bbe2e2678325a 325 Gene3D G3DSA:1.10.10.60 272 325 6.3E-13 T 28-03-2018 CU254_RS21395 723dd090c060c906db0bbe2e2678325a 325 SUPERFAMILY SSF46689 216 267 1.0E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS21395 723dd090c060c906db0bbe2e2678325a 325 SMART SM00342 233 316 1.8E-26 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS21395 723dd090c060c906db0bbe2e2678325a 325 Gene3D G3DSA:3.40.50.880 6 225 6.0E-55 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS21395 723dd090c060c906db0bbe2e2678325a 325 Pfam PF12833 Helix-turn-helix domain 239 317 3.5E-23 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS21395 723dd090c060c906db0bbe2e2678325a 325 SUPERFAMILY SSF46689 269 319 9.41E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS21395 723dd090c060c906db0bbe2e2678325a 325 Pfam PF01965 DJ-1/PfpI family 14 178 7.7E-24 T 28-03-2018 IPR002818 DJ-1/PfpI CU254_RS00965 c402d4bad3fb86b75f8f1eb927803622 348 Gene3D G3DSA:3.40.50.20 193 340 8.4E-21 T 28-03-2018 CU254_RS00965 c402d4bad3fb86b75f8f1eb927803622 348 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 144 7.9E-29 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CU254_RS00965 c402d4bad3fb86b75f8f1eb927803622 348 Gene3D G3DSA:3.90.180.10 1 192 1.7E-60 T 28-03-2018 CU254_RS00965 c402d4bad3fb86b75f8f1eb927803622 348 SUPERFAMILY SSF51735 151 312 1.91E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS00965 c402d4bad3fb86b75f8f1eb927803622 348 SMART SM00829 14 342 1.3E-6 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CU254_RS00965 c402d4bad3fb86b75f8f1eb927803622 348 SUPERFAMILY SSF50129 9 173 1.98E-55 T 28-03-2018 IPR011032 GroES-like CU254_RS00965 c402d4bad3fb86b75f8f1eb927803622 348 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 63 77 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CU254_RS00965 c402d4bad3fb86b75f8f1eb927803622 348 Pfam PF00107 Zinc-binding dehydrogenase 186 308 9.4E-20 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CU254_RS17160 d59d2c3f02d6860fc4331e5b6653ef08 987 SMART SM01217 772 842 1.8E-28 T 28-03-2018 IPR026891 Fibronectin type III-like domain CU254_RS17160 d59d2c3f02d6860fc4331e5b6653ef08 987 Gene3D G3DSA:2.60.40.10 739 855 7.0E-33 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS17160 d59d2c3f02d6860fc4331e5b6653ef08 987 SUPERFAMILY SSF49785 858 985 5.78E-18 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS17160 d59d2c3f02d6860fc4331e5b6653ef08 987 Gene3D G3DSA:3.20.20.300 64 382 1.2E-79 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CU254_RS17160 d59d2c3f02d6860fc4331e5b6653ef08 987 SMART SM00606 860 987 1.7E-15 T 28-03-2018 IPR006584 Cellulose binding, type IV GO:0030246 CU254_RS17160 d59d2c3f02d6860fc4331e5b6653ef08 987 Gene3D G3DSA:3.20.20.300 32 63 0.033 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CU254_RS17160 d59d2c3f02d6860fc4331e5b6653ef08 987 SUPERFAMILY SSF51445 34 388 8.21E-76 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS17160 d59d2c3f02d6860fc4331e5b6653ef08 987 SUPERFAMILY SSF50405 451 526 3.33E-7 T 28-03-2018 IPR008999 Actin cross-linking CU254_RS17160 d59d2c3f02d6860fc4331e5b6653ef08 987 SUPERFAMILY SSF52279 390 455 4.71E-46 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CU254_RS17160 d59d2c3f02d6860fc4331e5b6653ef08 987 SUPERFAMILY SSF52279 595 741 4.71E-46 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CU254_RS17160 d59d2c3f02d6860fc4331e5b6653ef08 987 PRINTS PR00133 Glycosyl hydrolase family 3 signature 197 213 2.9E-7 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CU254_RS17160 d59d2c3f02d6860fc4331e5b6653ef08 987 PRINTS PR00133 Glycosyl hydrolase family 3 signature 108 127 2.9E-7 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CU254_RS17160 d59d2c3f02d6860fc4331e5b6653ef08 987 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 88 350 2.1E-38 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CU254_RS17160 d59d2c3f02d6860fc4331e5b6653ef08 987 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 390 738 1.4E-59 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CU254_RS17160 d59d2c3f02d6860fc4331e5b6653ef08 987 Gene3D G3DSA:3.40.50.1700 383 738 3.6E-66 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CU254_RS17160 d59d2c3f02d6860fc4331e5b6653ef08 987 Pfam PF14310 Fibronectin type III-like domain 772 841 2.6E-22 T 28-03-2018 IPR026891 Fibronectin type III-like domain CU254_RS17160 d59d2c3f02d6860fc4331e5b6653ef08 987 Gene3D G3DSA:2.60.120.260 856 987 1.6E-13 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS17160 d59d2c3f02d6860fc4331e5b6653ef08 987 Pfam PF03422 Carbohydrate binding module (family 6) 869 978 7.1E-16 T 28-03-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 CU254_RS04040 b9fc9990f7cf63a3d2be949ef3574a78 375 SUPERFAMILY SSF46894 273 365 5.67E-11 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS04040 b9fc9990f7cf63a3d2be949ef3574a78 375 Pfam PF00486 Transcriptional regulatory protein, C terminal 300 363 1.9E-9 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS04040 b9fc9990f7cf63a3d2be949ef3574a78 375 Gene3D G3DSA:3.40.50.10090 41 167 6.7E-24 T 28-03-2018 CU254_RS04040 b9fc9990f7cf63a3d2be949ef3574a78 375 Pfam PF02602 Uroporphyrinogen-III synthase HemD 22 261 5.1E-39 T 28-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CU254_RS04040 b9fc9990f7cf63a3d2be949ef3574a78 375 SUPERFAMILY SSF69618 9 269 1.02E-57 T 28-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CU254_RS04040 b9fc9990f7cf63a3d2be949ef3574a78 375 Gene3D G3DSA:1.10.10.10 272 370 5.7E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS04040 b9fc9990f7cf63a3d2be949ef3574a78 375 SMART SM00862 294 363 8.0E-12 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS04040 b9fc9990f7cf63a3d2be949ef3574a78 375 Gene3D G3DSA:3.40.50.10090 168 271 9.9E-15 T 28-03-2018 CU254_RS19465 6e9d568c16ebff34107c311ffd668d17 135 Gene3D G3DSA:2.30.110.10 2 135 1.5E-28 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS19465 6e9d568c16ebff34107c311ffd668d17 135 SUPERFAMILY SSF50475 6 134 5.54E-24 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS19465 6e9d568c16ebff34107c311ffd668d17 135 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 5 96 5.7E-15 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CU254_RS19465 6e9d568c16ebff34107c311ffd668d17 135 TIGRFAM TIGR03668 Rv0121_F420: PPOX class probable F420-dependent enzyme, Rv0121 family 4 132 5.3E-50 T 28-03-2018 IPR019967 F420-dependent enzyme, PPOX class, family Rv0121, probable CU254_RS42495 d1325a4c3ce9d8d3f50fac82ec4d2fce 184 SMART SM00530 36 98 1.5E-5 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS42495 d1325a4c3ce9d8d3f50fac82ec4d2fce 184 Gene3D G3DSA:1.10.260.40 28 113 7.5E-8 T 28-03-2018 CU254_RS42495 d1325a4c3ce9d8d3f50fac82ec4d2fce 184 Pfam PF13560 Helix-turn-helix domain 34 95 6.6E-11 T 28-03-2018 CU254_RS26895 ddff2986674874031d164fd54e17d8b0 519 Pfam PF09423 PhoD-like phosphatase 155 500 2.5E-79 T 28-03-2018 IPR018946 Alkaline phosphatase D-related CU254_RS26895 ddff2986674874031d164fd54e17d8b0 519 Pfam PF16655 PhoD-like phosphatase, N-terminal domain 48 138 8.1E-22 T 28-03-2018 IPR032093 Phospholipase D, N-terminal CU254_RS26895 ddff2986674874031d164fd54e17d8b0 519 Gene3D G3DSA:3.60.21.10 143 519 5.0E-35 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CU254_RS26895 ddff2986674874031d164fd54e17d8b0 519 Gene3D G3DSA:2.60.40.10 43 133 3.1E-7 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS26895 ddff2986674874031d164fd54e17d8b0 519 SUPERFAMILY SSF49265 86 134 2.31E-5 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CU254_RS26895 ddff2986674874031d164fd54e17d8b0 519 SUPERFAMILY SSF56300 147 515 1.31E-36 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CU254_RS09165 ab02fb2575df6e5bff4b484b785a1b33 265 Gene3D G3DSA:3.60.110.10 1 265 5.0E-62 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CU254_RS09165 ab02fb2575df6e5bff4b484b785a1b33 265 Pfam PF00795 Carbon-nitrogen hydrolase 3 253 5.7E-36 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CU254_RS09165 ab02fb2575df6e5bff4b484b785a1b33 265 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 139 159 - T 28-03-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site CU254_RS09165 ab02fb2575df6e5bff4b484b785a1b33 265 SUPERFAMILY SSF56317 3 261 8.76E-61 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CU254_RS39940 749f6e434439d3c377ef9962c38b4d68 596 Pfam PF00474 Sodium:solute symporter family 297 500 2.4E-19 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CU254_RS39940 749f6e434439d3c377ef9962c38b4d68 596 Pfam PF00474 Sodium:solute symporter family 35 197 4.4E-24 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CU254_RS34975 eeffa2ff002c1313c79309bb2bf32ec9 379 Gene3D G3DSA:1.10.230.10 236 326 7.3E-22 T 28-03-2018 IPR016143 Citrate synthase-like, small alpha subdomain CU254_RS34975 eeffa2ff002c1313c79309bb2bf32ec9 379 ProSitePatterns PS00480 Citrate synthase signature. 254 266 - T 28-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 CU254_RS34975 eeffa2ff002c1313c79309bb2bf32ec9 379 PRINTS PR00143 Citrate synthase signature 172 187 6.4E-24 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CU254_RS34975 eeffa2ff002c1313c79309bb2bf32ec9 379 PRINTS PR00143 Citrate synthase signature 326 340 6.4E-24 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CU254_RS34975 eeffa2ff002c1313c79309bb2bf32ec9 379 PRINTS PR00143 Citrate synthase signature 306 322 6.4E-24 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CU254_RS34975 eeffa2ff002c1313c79309bb2bf32ec9 379 PRINTS PR00143 Citrate synthase signature 194 222 6.4E-24 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CU254_RS34975 eeffa2ff002c1313c79309bb2bf32ec9 379 PRINTS PR00143 Citrate synthase signature 247 267 6.4E-24 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CU254_RS34975 eeffa2ff002c1313c79309bb2bf32ec9 379 Gene3D G3DSA:1.10.580.10 4 95 2.3E-13 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain CU254_RS34975 eeffa2ff002c1313c79309bb2bf32ec9 379 Gene3D G3DSA:1.10.580.10 96 235 3.0E-35 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain CU254_RS34975 eeffa2ff002c1313c79309bb2bf32ec9 379 Pfam PF00285 Citrate synthase, C-terminal domain 19 355 2.3E-82 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CU254_RS34975 eeffa2ff002c1313c79309bb2bf32ec9 379 SUPERFAMILY SSF48256 16 366 6.54E-94 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CU254_RS39220 eb0020580d8e954b508ac6fb3681606f 108 Pfam PF01809 Haemolytic domain 27 91 4.3E-26 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CU254_RS39220 eb0020580d8e954b508ac6fb3681606f 108 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 39 91 9.0E-16 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CU254_RS39220 eb0020580d8e954b508ac6fb3681606f 108 SMART SM01234 24 91 2.3E-39 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CU254_RS39220 eb0020580d8e954b508ac6fb3681606f 108 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 24 92 23.562 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CU254_RS39220 eb0020580d8e954b508ac6fb3681606f 108 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 30 95 2.0E-23 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CU254_RS40760 5bdf063c56d06e84f48307b20af5c98f 333 SMART SM00421 263 320 3.1E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS40760 5bdf063c56d06e84f48307b20af5c98f 333 SUPERFAMILY SSF46785 10 63 6.0E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS40760 5bdf063c56d06e84f48307b20af5c98f 333 Pfam PF00196 Bacterial regulatory proteins, luxR family 270 317 1.9E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS40760 5bdf063c56d06e84f48307b20af5c98f 333 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 3 68 1.0E-8 T 28-03-2018 IPR002831 Transcription regulator TrmB, N-terminal CU254_RS40760 5bdf063c56d06e84f48307b20af5c98f 333 SUPERFAMILY SSF46894 270 327 3.74E-10 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS40760 5bdf063c56d06e84f48307b20af5c98f 333 Gene3D G3DSA:1.10.10.10 1 127 3.1E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS40760 5bdf063c56d06e84f48307b20af5c98f 333 Gene3D G3DSA:1.10.10.10 224 325 2.3E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS38380 910a040376001256da06e19c5bae426d 156 Gene3D G3DSA:1.10.10.10 1 139 2.5E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS38380 910a040376001256da06e19c5bae426d 156 Pfam PF01047 MarR family 47 94 2.8E-14 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS38380 910a040376001256da06e19c5bae426d 156 SMART SM00347 29 129 2.8E-15 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS38380 910a040376001256da06e19c5bae426d 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 1.7E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS38380 910a040376001256da06e19c5bae426d 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 1.7E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS38380 910a040376001256da06e19c5bae426d 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 53 69 1.7E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS38380 910a040376001256da06e19c5bae426d 156 SUPERFAMILY SSF46785 9 140 1.26E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS23185 f84698469dc234ce7a664818c26a35ff 401 Pfam PF07730 Histidine kinase 205 266 2.8E-13 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CU254_RS23185 f84698469dc234ce7a664818c26a35ff 401 Gene3D G3DSA:3.30.565.10 270 391 3.8E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS23185 f84698469dc234ce7a664818c26a35ff 401 SUPERFAMILY SSF55874 301 388 8.48E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS38560 538f44ef16c7ebce91068f7bd3bca19d 337 SUPERFAMILY SSF53807 45 318 5.89E-27 T 28-03-2018 CU254_RS38560 538f44ef16c7ebce91068f7bd3bca19d 337 Gene3D G3DSA:3.40.50.1980 30 172 4.6E-11 T 28-03-2018 CU254_RS38560 538f44ef16c7ebce91068f7bd3bca19d 337 Pfam PF01497 Periplasmic binding protein 71 313 3.6E-18 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CU254_RS38560 538f44ef16c7ebce91068f7bd3bca19d 337 Gene3D G3DSA:3.40.50.1980 173 337 1.6E-20 T 28-03-2018 CU254_RS05130 b03c8c5624523dd9973f95228ca8d3f7 205 SUPERFAMILY SSF48498 96 193 3.86E-12 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS05130 b03c8c5624523dd9973f95228ca8d3f7 205 Gene3D G3DSA:1.10.10.60 1 56 6.0E-15 T 28-03-2018 CU254_RS05130 b03c8c5624523dd9973f95228ca8d3f7 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 68 2.5E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS05130 b03c8c5624523dd9973f95228ca8d3f7 205 Pfam PF13305 WHG domain 99 180 2.7E-11 T 28-03-2018 IPR025996 WHG domain CU254_RS05130 b03c8c5624523dd9973f95228ca8d3f7 205 Gene3D G3DSA:1.10.10.60 57 78 2.2E-8 T 28-03-2018 CU254_RS05130 b03c8c5624523dd9973f95228ca8d3f7 205 SUPERFAMILY SSF46689 9 87 2.29E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS05130 b03c8c5624523dd9973f95228ca8d3f7 205 Gene3D G3DSA:1.10.357.10 79 205 2.6E-14 T 28-03-2018 CU254_RS28315 1d34da2a9b4df0472f3502f1be11ad0a 453 Gene3D G3DSA:3.40.1670.10 299 438 3.0E-35 T 28-03-2018 CU254_RS28315 1d34da2a9b4df0472f3502f1be11ad0a 453 SUPERFAMILY SSF143968 307 448 3.01E-39 T 28-03-2018 CU254_RS28315 1d34da2a9b4df0472f3502f1be11ad0a 453 SUPERFAMILY SSF50475 18 296 2.24E-74 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS28315 1d34da2a9b4df0472f3502f1be11ad0a 453 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 20 401 5.2E-98 T 28-03-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 CU254_RS28315 1d34da2a9b4df0472f3502f1be11ad0a 453 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 20 426 8.8E-88 T 28-03-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 CU254_RS29985 cbd57b52a80c4d21ff54979b8a7aaf05 107 Gene3D G3DSA:3.30.70.1060 1 107 1.1E-30 T 28-03-2018 CU254_RS29985 cbd57b52a80c4d21ff54979b8a7aaf05 107 Pfam PF03795 YCII-related domain 1 104 6.8E-13 T 28-03-2018 IPR005545 YCII-related CU254_RS29985 cbd57b52a80c4d21ff54979b8a7aaf05 107 SUPERFAMILY SSF54909 1 106 2.32E-23 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS38665 d5ddfd5604e1092ece26f283127c3fbe 322 SUPERFAMILY SSF55729 163 307 1.32E-26 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS38665 d5ddfd5604e1092ece26f283127c3fbe 322 Pfam PF12802 MarR family 50 106 1.4E-13 T 28-03-2018 CU254_RS38665 d5ddfd5604e1092ece26f283127c3fbe 322 Pfam PF00583 Acetyltransferase (GNAT) family 202 298 2.9E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS38665 d5ddfd5604e1092ece26f283127c3fbe 322 SMART SM00347 42 142 8.4E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS38665 d5ddfd5604e1092ece26f283127c3fbe 322 Gene3D G3DSA:3.40.630.30 160 322 4.2E-26 T 28-03-2018 CU254_RS38665 d5ddfd5604e1092ece26f283127c3fbe 322 SUPERFAMILY SSF46785 24 157 1.14E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS38665 d5ddfd5604e1092ece26f283127c3fbe 322 Gene3D G3DSA:1.10.10.10 5 159 4.5E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS08475 ee56e70bc028521e721b84a7db36254e 136 Pfam PF01894 Uncharacterised protein family UPF0047 18 130 3.1E-21 T 28-03-2018 IPR001602 Uncharacterised protein family UPF0047 CU254_RS08475 ee56e70bc028521e721b84a7db36254e 136 SUPERFAMILY SSF111038 2 131 2.22E-31 T 28-03-2018 IPR001602 Uncharacterised protein family UPF0047 CU254_RS08475 ee56e70bc028521e721b84a7db36254e 136 Gene3D G3DSA:2.60.120.460 1 134 1.1E-28 T 28-03-2018 IPR001602 Uncharacterised protein family UPF0047 CU254_RS03170 6bc0e5f5558b344228026d87d68b92c2 194 Pfam PF04203 Sortase family 49 190 1.2E-18 T 28-03-2018 IPR005754 Sortase family CU254_RS03170 6bc0e5f5558b344228026d87d68b92c2 194 SUPERFAMILY SSF63817 40 191 6.54E-17 T 28-03-2018 IPR023365 Sortase domain CU254_RS03170 6bc0e5f5558b344228026d87d68b92c2 194 Gene3D G3DSA:2.40.260.10 23 194 8.9E-28 T 28-03-2018 IPR023365 Sortase domain CU254_RS06655 290e35d4eece7cc332b823774186f984 534 Pfam PF01274 Malate synthase 10 528 1.5E-197 T 28-03-2018 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 CU254_RS06655 290e35d4eece7cc332b823774186f984 534 TIGRFAM TIGR01344 malate_syn_A: malate synthase A 22 529 1.8E-238 T 28-03-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 CU254_RS06655 290e35d4eece7cc332b823774186f984 534 Gene3D G3DSA:3.20.20.360 79 415 5.6E-118 T 28-03-2018 CU254_RS06655 290e35d4eece7cc332b823774186f984 534 Gene3D G3DSA:1.20.1220.12 416 530 2.8E-39 T 28-03-2018 CU254_RS06655 290e35d4eece7cc332b823774186f984 534 ProSitePatterns PS00510 Malate synthase signature. 266 281 - T 28-03-2018 IPR019830 Malate synthase, conserved site GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 CU254_RS06655 290e35d4eece7cc332b823774186f984 534 SUPERFAMILY SSF51645 6 530 6.93E-184 T 28-03-2018 IPR011076 Malate synthase-like GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 CU254_RS06655 290e35d4eece7cc332b823774186f984 534 PIRSF PIRSF001363 1 532 2.6E-241 T 28-03-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 CU254_RS13375 72ae549856083115f464f861319de71f 265 SUPERFAMILY SSF52540 4 225 4.69E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS13375 72ae549856083115f464f861319de71f 265 SMART SM00382 30 216 1.4E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS13375 72ae549856083115f464f861319de71f 265 Gene3D G3DSA:3.40.50.300 2 247 5.6E-68 T 28-03-2018 CU254_RS13375 72ae549856083115f464f861319de71f 265 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS13375 72ae549856083115f464f861319de71f 265 Pfam PF00005 ABC transporter 22 164 3.2E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS26100 474f0ba27a4460eae8b5bf405e3a5e0a 457 SUPERFAMILY SSF48179 241 376 1.87E-13 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CU254_RS26100 474f0ba27a4460eae8b5bf405e3a5e0a 457 Gene3D G3DSA:3.40.50.720 23 230 1.8E-7 T 28-03-2018 CU254_RS26100 474f0ba27a4460eae8b5bf405e3a5e0a 457 Gene3D G3DSA:1.10.1040.10 246 379 3.3E-17 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CU254_RS26100 474f0ba27a4460eae8b5bf405e3a5e0a 457 Pfam PF02317 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain 241 375 2.1E-14 T 28-03-2018 IPR003421 Opine dehydrogenase GO:0016491|GO:0050662|GO:0055114 CU254_RS32355 d7b47d67b5de7a1782aa9da7095981ac 234 Pfam PF08241 Methyltransferase domain 44 137 3.7E-22 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CU254_RS32355 d7b47d67b5de7a1782aa9da7095981ac 234 Gene3D G3DSA:3.40.50.150 21 231 2.4E-34 T 28-03-2018 CU254_RS32355 d7b47d67b5de7a1782aa9da7095981ac 234 SUPERFAMILY SSF53335 4 200 2.71E-37 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS03245 3d2c7a7ba310c979ec683d777ec39e2f 202 Gene3D G3DSA:1.10.10.10 7 97 6.6E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS03245 3d2c7a7ba310c979ec683d777ec39e2f 202 SUPERFAMILY SSF46785 10 181 3.59E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS03245 3d2c7a7ba310c979ec683d777ec39e2f 202 Pfam PF03551 Transcriptional regulator PadR-like family 13 89 3.9E-14 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CU254_RS34190 6ef192e49e83ce935834e4b0be9b01fd 233 SUPERFAMILY SSF52172 7 174 5.83E-47 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS34190 6ef192e49e83ce935834e4b0be9b01fd 233 SMART SM00448 6 116 5.2E-50 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS34190 6ef192e49e83ce935834e4b0be9b01fd 233 Pfam PF00072 Response regulator receiver domain 8 116 3.7E-33 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS34190 6ef192e49e83ce935834e4b0be9b01fd 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 155 227 3.1E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS34190 6ef192e49e83ce935834e4b0be9b01fd 233 SMART SM00862 153 228 1.0E-26 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS34190 6ef192e49e83ce935834e4b0be9b01fd 233 Gene3D G3DSA:3.40.50.2300 1 126 2.7E-41 T 28-03-2018 CU254_RS34190 6ef192e49e83ce935834e4b0be9b01fd 233 Gene3D G3DSA:1.10.10.10 127 233 3.7E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS31235 7d11a66df99a8769dafc5fc4db30a9f6 424 Gene3D G3DSA:3.65.10.10 22 220 7.4E-48 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CU254_RS31235 7d11a66df99a8769dafc5fc4db30a9f6 424 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 3 416 1.8E-160 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CU254_RS31235 7d11a66df99a8769dafc5fc4db30a9f6 424 SUPERFAMILY SSF55205 4 417 8.9E-126 T 28-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CU254_RS31235 7d11a66df99a8769dafc5fc4db30a9f6 424 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 8 407 8.1E-99 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CU254_RS31235 7d11a66df99a8769dafc5fc4db30a9f6 424 Gene3D G3DSA:3.65.10.10 221 419 2.4E-43 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CU254_RS31235 7d11a66df99a8769dafc5fc4db30a9f6 424 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 2 417 38.908 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CU254_RS05210 a490caf14b96d4a649cb5bb2765c4d1c 461 SUPERFAMILY SSF53850 58 459 6.14E-52 T 28-03-2018 CU254_RS05210 a490caf14b96d4a649cb5bb2765c4d1c 461 Pfam PF13416 Bacterial extracellular solute-binding protein 79 359 8.3E-23 T 28-03-2018 CU254_RS05210 a490caf14b96d4a649cb5bb2765c4d1c 461 Gene3D G3DSA:3.40.190.10 245 389 1.0E-5 T 28-03-2018 CU254_RS05210 a490caf14b96d4a649cb5bb2765c4d1c 461 Gene3D G3DSA:3.40.190.10 54 228 5.5E-31 T 28-03-2018 CU254_RS36780 c9dc1b2ff452d529b3385cab4337ff6b 357 SUPERFAMILY SSF55979 121 226 4.5E-11 T 28-03-2018 CU254_RS36780 c9dc1b2ff452d529b3385cab4337ff6b 357 SUPERFAMILY SSF55979 7 104 1.81E-8 T 28-03-2018 CU254_RS36780 c9dc1b2ff452d529b3385cab4337ff6b 357 Gene3D G3DSA:3.10.150.10 3 108 2.7E-13 T 28-03-2018 CU254_RS36780 c9dc1b2ff452d529b3385cab4337ff6b 357 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 27 354 2.7E-41 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CU254_RS36780 c9dc1b2ff452d529b3385cab4337ff6b 357 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 235 348 3.9E-18 T 28-03-2018 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CU254_RS36780 c9dc1b2ff452d529b3385cab4337ff6b 357 SUPERFAMILY SSF55979 238 354 1.84E-17 T 28-03-2018 CU254_RS36780 c9dc1b2ff452d529b3385cab4337ff6b 357 SMART SM00480 11 352 2.7E-16 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CU254_RS36780 c9dc1b2ff452d529b3385cab4337ff6b 357 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 27 105 8.4E-10 T 28-03-2018 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CU254_RS36780 c9dc1b2ff452d529b3385cab4337ff6b 357 Gene3D G3DSA:3.10.150.10 118 234 3.6E-20 T 28-03-2018 CU254_RS36780 c9dc1b2ff452d529b3385cab4337ff6b 357 Gene3D G3DSA:3.10.150.10 235 355 1.5E-18 T 28-03-2018 CU254_RS36780 c9dc1b2ff452d529b3385cab4337ff6b 357 Pfam PF02767 DNA polymerase III beta subunit, central domain 124 228 1.3E-12 T 28-03-2018 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CU254_RS39625 24cc2cab6248b20b6b3fcfc71b8e3522 255 SUPERFAMILY SSF52540 1 235 7.84E-73 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS39625 24cc2cab6248b20b6b3fcfc71b8e3522 255 Gene3D G3DSA:3.40.50.300 1 255 4.0E-77 T 28-03-2018 CU254_RS39625 24cc2cab6248b20b6b3fcfc71b8e3522 255 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS39625 24cc2cab6248b20b6b3fcfc71b8e3522 255 Pfam PF00005 ABC transporter 19 163 1.3E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS39625 24cc2cab6248b20b6b3fcfc71b8e3522 255 SMART SM00382 28 221 2.5E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS29900 898d6e558b40337836ddb08bdb49bd79 482 Pfam PF00764 Arginosuccinate synthase 16 404 4.7E-58 T 28-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CU254_RS29900 898d6e558b40337836ddb08bdb49bd79 482 SUPERFAMILY SSF52402 5 185 4.19E-31 T 28-03-2018 CU254_RS29900 898d6e558b40337836ddb08bdb49bd79 482 SUPERFAMILY SSF69864 190 433 1.26E-75 T 28-03-2018 CU254_RS29900 898d6e558b40337836ddb08bdb49bd79 482 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 129 140 - T 28-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CU254_RS29900 898d6e558b40337836ddb08bdb49bd79 482 TIGRFAM TIGR00032 argG: argininosuccinate synthase 13 420 9.1E-140 T 28-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CU254_RS29900 898d6e558b40337836ddb08bdb49bd79 482 Gene3D G3DSA:3.40.50.620 2 178 9.4E-19 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS29900 898d6e558b40337836ddb08bdb49bd79 482 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 17 25 - T 28-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CU254_RS29900 898d6e558b40337836ddb08bdb49bd79 482 Gene3D G3DSA:1.10.287.400 378 438 7.3E-31 T 28-03-2018 IPR024073 Argininosuccinate synthetase mutimerisation domain, C-terminal tail GO:0042803 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CU254_RS29900 898d6e558b40337836ddb08bdb49bd79 482 Hamap MF_00581 Argininosuccinate synthase [argG]. 1 473 78.126 T 28-03-2018 IPR023437 Argininosuccinate synthase, type 2 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CU254_RS29900 898d6e558b40337836ddb08bdb49bd79 482 Gene3D G3DSA:3.90.1260.10 179 374 2.3E-58 T 28-03-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CU254_RS19985 119a42036571ed4c96b1c3542d73de42 241 Gene3D G3DSA:3.60.20.10 15 233 1.7E-70 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CU254_RS19985 119a42036571ed4c96b1c3542d73de42 241 SUPERFAMILY SSF56235 18 241 2.16E-67 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CU254_RS19985 119a42036571ed4c96b1c3542d73de42 241 Pfam PF06267 Family of unknown function (DUF1028) 18 208 3.2E-59 T 28-03-2018 IPR010430 Protein of unknown function DUF1028 CU254_RS40400 399cb9a89ccece51b1aecfb339353fdb 283 SUPERFAMILY SSF51735 2 246 8.6E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS40400 399cb9a89ccece51b1aecfb339353fdb 283 Gene3D G3DSA:3.40.50.720 1 255 3.1E-19 T 28-03-2018 CU254_RS40400 399cb9a89ccece51b1aecfb339353fdb 283 Pfam PF13460 NAD(P)H-binding 6 180 2.3E-15 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS12465 a18d4831e4923801a59f1d35e25a36e0 789 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 152 701 2.5E-203 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CU254_RS12465 a18d4831e4923801a59f1d35e25a36e0 789 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 28 133 3.3E-18 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CU254_RS12465 a18d4831e4923801a59f1d35e25a36e0 789 Gene3D G3DSA:3.30.365.10 155 263 4.5E-34 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CU254_RS12465 a18d4831e4923801a59f1d35e25a36e0 789 SUPERFAMILY SSF56003 133 771 7.2E-199 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CU254_RS12465 a18d4831e4923801a59f1d35e25a36e0 789 Gene3D G3DSA:3.90.1170.50 11 133 1.4E-26 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CU254_RS12465 a18d4831e4923801a59f1d35e25a36e0 789 SUPERFAMILY SSF54665 8 133 1.31E-29 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CU254_RS12465 a18d4831e4923801a59f1d35e25a36e0 789 Gene3D G3DSA:3.30.365.10 607 773 1.4E-54 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CU254_RS12465 a18d4831e4923801a59f1d35e25a36e0 789 Gene3D G3DSA:3.30.365.10 264 425 7.7E-56 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CU254_RS12465 a18d4831e4923801a59f1d35e25a36e0 789 Gene3D G3DSA:3.30.365.10 445 606 7.9E-54 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CU254_RS12465 a18d4831e4923801a59f1d35e25a36e0 789 SMART SM01008 27 133 7.5E-31 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CU254_RS12465 a18d4831e4923801a59f1d35e25a36e0 789 TIGRFAM TIGR02965 xanthine_xdhB: xanthine dehydrogenase, molybdopterin binding subunit 13 770 3.6E-284 T 28-03-2018 IPR014309 Xanthine dehydrogenase, molybdopterin binding subunit GO:0030151 KEGG: 00230+1.17.1.4+1.17.3.2|KEGG: 00232+1.17.3.2|KEGG: 00983+1.17.3.2|MetaCyc: PWY-5497|MetaCyc: PWY-5695|MetaCyc: PWY-6538|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-6999 CU254_RS09950 07846d14da3639281d0b2d1d899e36c9 398 Gene3D G3DSA:1.20.5.1230 135 362 3.5E-6 T 28-03-2018 CU254_RS09950 07846d14da3639281d0b2d1d899e36c9 398 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 18 302 6.3E-66 T 28-03-2018 IPR005693 Virulence factor Mce protein CU254_RS09950 07846d14da3639281d0b2d1d899e36c9 398 Pfam PF02470 MlaD protein 38 112 4.4E-14 T 28-03-2018 IPR003399 Mce/MlaD CU254_RS07390 9206d18182e36c685ae1cb23f4128500 362 Gene3D G3DSA:4.10.1250.10 235 277 1.6E-16 T 28-03-2018 CU254_RS07390 9206d18182e36c685ae1cb23f4128500 362 Pfam PF01571 Aminomethyltransferase folate-binding domain 6 256 3.2E-95 T 28-03-2018 IPR006222 Glycine cleavage T-protein-like, N-terminal CU254_RS07390 9206d18182e36c685ae1cb23f4128500 362 Hamap MF_00259 Aminomethyltransferase [gcvT]. 1 361 43.224 T 28-03-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CU254_RS07390 9206d18182e36c685ae1cb23f4128500 362 Gene3D G3DSA:3.30.1360.120 1 128 8.8E-33 T 28-03-2018 CU254_RS07390 9206d18182e36c685ae1cb23f4128500 362 Gene3D G3DSA:3.30.1360.120 129 234 9.0E-33 T 28-03-2018 CU254_RS07390 9206d18182e36c685ae1cb23f4128500 362 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 264 355 2.2E-25 T 28-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CU254_RS07390 9206d18182e36c685ae1cb23f4128500 362 SUPERFAMILY SSF101790 272 360 3.6E-26 T 28-03-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain CU254_RS07390 9206d18182e36c685ae1cb23f4128500 362 PIRSF PIRSF006487 1 362 3.3E-101 T 28-03-2018 CU254_RS07390 9206d18182e36c685ae1cb23f4128500 362 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 3 360 4.4E-110 T 28-03-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 CU254_RS07390 9206d18182e36c685ae1cb23f4128500 362 Gene3D G3DSA:2.40.30.110 280 362 1.1E-26 T 28-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CU254_RS07390 9206d18182e36c685ae1cb23f4128500 362 SUPERFAMILY SSF103025 4 277 6.54E-100 T 28-03-2018 CU254_RS04030 2dff99755aa079d03cefe656faa4d9f1 834 Gene3D G3DSA:3.50.50.60 246 331 7.4E-8 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS04030 2dff99755aa079d03cefe656faa4d9f1 834 SUPERFAMILY SSF55124 498 633 7.41E-26 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CU254_RS04030 2dff99755aa079d03cefe656faa4d9f1 834 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 294 4.9E-46 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS04030 2dff99755aa079d03cefe656faa4d9f1 834 Pfam PF04324 BFD-like [2Fe-2S] binding domain 484 525 5.8E-6 T 28-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain CU254_RS04030 2dff99755aa079d03cefe656faa4d9f1 834 Pfam PF04324 BFD-like [2Fe-2S] binding domain 419 467 5.3E-12 T 28-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain CU254_RS04030 2dff99755aa079d03cefe656faa4d9f1 834 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 4 793 0.0 T 28-03-2018 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 CU254_RS04030 2dff99755aa079d03cefe656faa4d9f1 834 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 624 760 1.2E-17 T 28-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CU254_RS04030 2dff99755aa079d03cefe656faa4d9f1 834 Gene3D G3DSA:3.90.480.10 332 621 1.1E-8 T 28-03-2018 CU254_RS04030 2dff99755aa079d03cefe656faa4d9f1 834 PRINTS PR00397 Sirohaem Fe-binding site signature 671 689 6.4E-6 T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CU254_RS04030 2dff99755aa079d03cefe656faa4d9f1 834 PRINTS PR00397 Sirohaem Fe-binding site signature 628 646 6.4E-6 T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CU254_RS04030 2dff99755aa079d03cefe656faa4d9f1 834 SUPERFAMILY SSF56014 625 799 1.23E-49 T 28-03-2018 CU254_RS04030 2dff99755aa079d03cefe656faa4d9f1 834 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 283 7.2E-16 T 28-03-2018 CU254_RS04030 2dff99755aa079d03cefe656faa4d9f1 834 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 100 118 7.2E-16 T 28-03-2018 CU254_RS04030 2dff99755aa079d03cefe656faa4d9f1 834 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 149 167 7.2E-16 T 28-03-2018 CU254_RS04030 2dff99755aa079d03cefe656faa4d9f1 834 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 234 250 7.2E-16 T 28-03-2018 CU254_RS04030 2dff99755aa079d03cefe656faa4d9f1 834 SUPERFAMILY SSF51905 151 309 7.51E-27 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS04030 2dff99755aa079d03cefe656faa4d9f1 834 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 552 613 1.9E-11 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CU254_RS04030 2dff99755aa079d03cefe656faa4d9f1 834 Gene3D G3DSA:3.50.50.60 105 243 9.7E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS04030 2dff99755aa079d03cefe656faa4d9f1 834 Gene3D G3DSA:3.30.413.10 623 798 9.3E-38 T 28-03-2018 CU254_RS04030 2dff99755aa079d03cefe656faa4d9f1 834 PIRSF PIRSF037149 1 827 0.0 T 28-03-2018 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 CU254_RS04030 2dff99755aa079d03cefe656faa4d9f1 834 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 671 687 - T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CU254_RS04030 2dff99755aa079d03cefe656faa4d9f1 834 Gene3D G3DSA:3.50.50.60 1 104 8.3E-11 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS04030 2dff99755aa079d03cefe656faa4d9f1 834 SUPERFAMILY SSF51905 3 191 6.33E-38 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS28395 0e33151ae2949ad511bea1185f833e51 1510 SUPERFAMILY SSF69336 1228 1488 1.96E-93 T 28-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 CU254_RS28395 0e33151ae2949ad511bea1185f833e51 1510 Gene3D G3DSA:2.160.20.60 1234 1504 2.5E-114 T 28-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 CU254_RS28395 0e33151ae2949ad511bea1185f833e51 1510 Pfam PF01493 GXGXG motif 1259 1441 2.0E-80 T 28-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 CU254_RS28395 0e33151ae2949ad511bea1185f833e51 1510 SUPERFAMILY SSF56235 23 438 1.99E-151 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CU254_RS28395 0e33151ae2949ad511bea1185f833e51 1510 Gene3D G3DSA:3.20.20.70 796 1231 1.6E-158 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS28395 0e33151ae2949ad511bea1185f833e51 1510 SUPERFAMILY SSF51395 458 1215 6.92E-261 T 28-03-2018 CU254_RS28395 0e33151ae2949ad511bea1185f833e51 1510 Pfam PF00310 Glutamine amidotransferases class-II 23 436 2.4E-182 T 28-03-2018 IPR017932 Glutamine amidotransferase type 2 domain CU254_RS28395 0e33151ae2949ad511bea1185f833e51 1510 Gene3D G3DSA:3.60.20.10 23 445 5.1E-170 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CU254_RS28395 0e33151ae2949ad511bea1185f833e51 1510 Gene3D G3DSA:3.20.20.70 446 795 2.4E-98 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS28395 0e33151ae2949ad511bea1185f833e51 1510 Pfam PF04898 Glutamate synthase central domain 462 749 5.8E-110 T 28-03-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 CU254_RS28395 0e33151ae2949ad511bea1185f833e51 1510 Pfam PF01645 Conserved region in glutamate synthase 814 1179 5.7E-154 T 28-03-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 CU254_RS09900 76543f39dec27b6e095ea28351f65e20 342 Gene3D G3DSA:1.20.140.10 198 320 4.6E-35 T 28-03-2018 CU254_RS09900 76543f39dec27b6e095ea28351f65e20 342 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 90 7.8E-7 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS09900 76543f39dec27b6e095ea28351f65e20 342 Gene3D G3DSA:1.10.540.10 1 119 1.3E-15 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS09900 76543f39dec27b6e095ea28351f65e20 342 SUPERFAMILY SSF56645 2 183 4.65E-19 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS09900 76543f39dec27b6e095ea28351f65e20 342 SUPERFAMILY SSF47203 202 336 8.86E-37 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS09900 76543f39dec27b6e095ea28351f65e20 342 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 205 328 9.7E-31 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS04915 279d58cff55d64f80821fa5863f9db70 261 Gene3D G3DSA:3.30.450.40 77 259 9.3E-50 T 28-03-2018 IPR029016 GAF domain-like CU254_RS04915 279d58cff55d64f80821fa5863f9db70 261 Pfam PF01614 Bacterial transcriptional regulator 127 250 2.5E-20 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal CU254_RS04915 279d58cff55d64f80821fa5863f9db70 261 SMART SM00346 6 96 5.4E-19 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS04915 279d58cff55d64f80821fa5863f9db70 261 SUPERFAMILY SSF46785 6 79 4.49E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS04915 279d58cff55d64f80821fa5863f9db70 261 Pfam PF09339 IclR helix-turn-helix domain 8 57 1.3E-12 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS04915 279d58cff55d64f80821fa5863f9db70 261 SUPERFAMILY SSF55781 71 256 2.35E-40 T 28-03-2018 IPR029016 GAF domain-like CU254_RS04915 279d58cff55d64f80821fa5863f9db70 261 Gene3D G3DSA:1.10.10.10 3 76 7.0E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS21010 2e0cdcbad67cde52577f26891910d9a7 458 Gene3D G3DSA:1.25.40.10 134 457 2.1E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS21010 2e0cdcbad67cde52577f26891910d9a7 458 SUPERFAMILY SSF47413 8 62 1.72E-9 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS21010 2e0cdcbad67cde52577f26891910d9a7 458 SMART SM00530 7 62 3.5E-5 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS21010 2e0cdcbad67cde52577f26891910d9a7 458 Gene3D G3DSA:1.10.260.40 8 72 9.4E-13 T 28-03-2018 CU254_RS21010 2e0cdcbad67cde52577f26891910d9a7 458 Pfam PF13560 Helix-turn-helix domain 10 65 2.9E-8 T 28-03-2018 CU254_RS07205 69b3f920b24655b853eb630d988da0d8 128 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 78 1.0E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS07205 69b3f920b24655b853eb630d988da0d8 128 SMART SM00345 19 78 1.0E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS07205 69b3f920b24655b853eb630d988da0d8 128 Gene3D G3DSA:1.10.10.10 5 80 3.8E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS07205 69b3f920b24655b853eb630d988da0d8 128 SUPERFAMILY SSF46785 8 82 1.97E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS18650 d022ce30179ff0078ee23e45a0c1d69c 466 Pfam PF00083 Sugar (and other) transporter 48 439 2.6E-46 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CU254_RS18650 d022ce30179ff0078ee23e45a0c1d69c 466 Gene3D G3DSA:1.20.1250.20 6 212 1.7E-36 T 28-03-2018 CU254_RS18650 d022ce30179ff0078ee23e45a0c1d69c 466 SUPERFAMILY SSF103473 2 455 1.12E-69 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS18650 d022ce30179ff0078ee23e45a0c1d69c 466 Gene3D G3DSA:1.20.1250.20 235 465 2.2E-24 T 28-03-2018 CU254_RS18985 ec7ea3ea300417e06dba9425d7954f07 115 Hamap MF_01483 RNA polymerase-binding protein RbpA [rbpA]. 16 112 23.789 T 28-03-2018 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 CU254_RS18985 ec7ea3ea300417e06dba9425d7954f07 115 Pfam PF13397 RNA polymerase-binding protein 4 107 1.2E-41 T 28-03-2018 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 CU254_RS13485 d3376a703c26433f08e65232aa881d92 243 SUPERFAMILY SSF51658 8 238 9.26E-31 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CU254_RS13485 d3376a703c26433f08e65232aa881d92 243 Gene3D G3DSA:3.20.20.150 1 240 7.7E-33 T 28-03-2018 CU254_RS13485 d3376a703c26433f08e65232aa881d92 243 Pfam PF01261 Xylose isomerase-like TIM barrel 41 202 1.6E-16 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CU254_RS26310 5a24a8a9b4dc331ae7ded8496163fef2 188 Gene3D G3DSA:1.20.1290.10 15 184 1.5E-25 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CU254_RS26310 5a24a8a9b4dc331ae7ded8496163fef2 188 Pfam PF02627 Carboxymuconolactone decarboxylase family 54 124 1.0E-5 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CU254_RS26310 5a24a8a9b4dc331ae7ded8496163fef2 188 SUPERFAMILY SSF69118 1 175 7.3E-36 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CU254_RS06450 9cc37d00a4cf8ba01cea7b6598ea348c 122 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 9 93 1.1E-24 T 28-03-2018 IPR023845 Domain of unknown function DUF3817, transmembrane CU254_RS06450 9cc37d00a4cf8ba01cea7b6598ea348c 122 Pfam PF12823 Domain of unknown function (DUF3817) 8 94 8.5E-24 T 28-03-2018 IPR023845 Domain of unknown function DUF3817, transmembrane CU254_RS08710 c10fea0779bcff92e9e20ed469347690 333 Pfam PF04055 Radical SAM superfamily 81 231 4.7E-11 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CU254_RS08710 c10fea0779bcff92e9e20ed469347690 333 SMART SM00729 71 277 1.1E-14 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CU254_RS08710 c10fea0779bcff92e9e20ed469347690 333 PIRSF PIRSF005963 2 318 2.5E-119 T 28-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CU254_RS08710 c10fea0779bcff92e9e20ed469347690 333 SUPERFAMILY SSF102114 35 296 4.19E-59 T 28-03-2018 CU254_RS08710 c10fea0779bcff92e9e20ed469347690 333 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 24 60 6.3E-8 T 28-03-2018 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CU254_RS08710 c10fea0779bcff92e9e20ed469347690 333 Hamap MF_00206 Lipoyl synthase [lipA]. 1 307 138.289 T 28-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CU254_RS08710 c10fea0779bcff92e9e20ed469347690 333 Gene3D G3DSA:3.20.20.70 29 320 4.7E-21 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS08710 c10fea0779bcff92e9e20ed469347690 333 TIGRFAM TIGR00510 lipA: lipoyl synthase 18 303 2.7E-98 T 28-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CU254_RS31550 2ecfe393529f4868ee67c987eec806b5 197 SUPERFAMILY SSF48498 88 196 4.15E-20 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS31550 2ecfe393529f4868ee67c987eec806b5 197 Gene3D G3DSA:1.10.357.10 57 196 6.5E-13 T 28-03-2018 CU254_RS31550 2ecfe393529f4868ee67c987eec806b5 197 Gene3D G3DSA:1.10.10.60 8 56 2.4E-10 T 28-03-2018 CU254_RS31550 2ecfe393529f4868ee67c987eec806b5 197 SUPERFAMILY SSF46689 7 72 4.59E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS31550 2ecfe393529f4868ee67c987eec806b5 197 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 88 196 5.2E-23 T 28-03-2018 CU254_RS31550 2ecfe393529f4868ee67c987eec806b5 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 57 1.1E-4 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS38830 e301595f7cc8bcf4969d8a432becf22a 217 SMART SM00448 2 117 4.1E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS38830 e301595f7cc8bcf4969d8a432becf22a 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 7.5E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS38830 e301595f7cc8bcf4969d8a432becf22a 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 7.5E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS38830 e301595f7cc8bcf4969d8a432becf22a 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 7.5E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS38830 e301595f7cc8bcf4969d8a432becf22a 217 Gene3D G3DSA:3.40.50.2300 1 135 3.4E-34 T 28-03-2018 CU254_RS38830 e301595f7cc8bcf4969d8a432becf22a 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 210 1.0E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS38830 e301595f7cc8bcf4969d8a432becf22a 217 SUPERFAMILY SSF46894 148 216 7.48E-19 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS38830 e301595f7cc8bcf4969d8a432becf22a 217 Gene3D G3DSA:1.10.10.10 136 215 1.1E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS38830 e301595f7cc8bcf4969d8a432becf22a 217 SMART SM00421 153 210 2.2E-21 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS38830 e301595f7cc8bcf4969d8a432becf22a 217 SUPERFAMILY SSF52172 2 132 1.99E-30 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS38830 e301595f7cc8bcf4969d8a432becf22a 217 Pfam PF00072 Response regulator receiver domain 4 118 3.0E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS38830 e301595f7cc8bcf4969d8a432becf22a 217 ProSitePatterns PS00622 LuxR-type HTH domain signature. 170 197 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS15445 36f69e261abb9dae9c1196415fe3a635 597 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 389 544 1.1E-28 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CU254_RS15445 36f69e261abb9dae9c1196415fe3a635 597 SUPERFAMILY SSF52467 156 358 1.12E-42 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CU254_RS15445 36f69e261abb9dae9c1196415fe3a635 597 Gene3D G3DSA:3.40.50.1220 189 350 2.7E-36 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CU254_RS15445 36f69e261abb9dae9c1196415fe3a635 597 Gene3D G3DSA:3.40.50.970 1 184 2.2E-48 T 28-03-2018 CU254_RS15445 36f69e261abb9dae9c1196415fe3a635 597 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 199 329 1.6E-26 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CU254_RS15445 36f69e261abb9dae9c1196415fe3a635 597 SUPERFAMILY SSF52518 3 185 7.31E-48 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS15445 36f69e261abb9dae9c1196415fe3a635 597 Gene3D G3DSA:3.40.50.970 351 564 4.9E-41 T 28-03-2018 CU254_RS15445 36f69e261abb9dae9c1196415fe3a635 597 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 173 4.3E-48 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CU254_RS15445 36f69e261abb9dae9c1196415fe3a635 597 SUPERFAMILY SSF52518 366 563 1.0E-51 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS15445 36f69e261abb9dae9c1196415fe3a635 597 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 426 445 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CU254_RS11790 6ecc1b843adfff9b0fd47d1cbb3a65df 308 SUPERFAMILY SSF52540 3 221 1.19E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS11790 6ecc1b843adfff9b0fd47d1cbb3a65df 308 Pfam PF00005 ABC transporter 22 160 3.1E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS11790 6ecc1b843adfff9b0fd47d1cbb3a65df 308 Gene3D G3DSA:3.40.50.300 2 247 4.0E-58 T 28-03-2018 CU254_RS11790 6ecc1b843adfff9b0fd47d1cbb3a65df 308 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS11790 6ecc1b843adfff9b0fd47d1cbb3a65df 308 SMART SM00382 30 208 3.2E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS36940 e6aea445d5751c7796965346136681b5 196 SUPERFAMILY SSF55469 7 194 6.81E-39 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CU254_RS36940 e6aea445d5751c7796965346136681b5 196 Pfam PF00881 Nitroreductase family 15 60 8.6E-10 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CU254_RS36940 e6aea445d5751c7796965346136681b5 196 Pfam PF00881 Nitroreductase family 78 156 1.6E-8 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CU254_RS36940 e6aea445d5751c7796965346136681b5 196 Gene3D G3DSA:3.40.109.10 1 195 1.9E-38 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CU254_RS42050 ee138d92a014c19186a9c3c8e1ea824f 283 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 11 216 2.7E-33 T 28-03-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 CU254_RS42050 ee138d92a014c19186a9c3c8e1ea824f 283 SUPERFAMILY SSF51621 9 227 3.49E-55 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CU254_RS42050 ee138d92a014c19186a9c3c8e1ea824f 283 Gene3D G3DSA:3.20.20.360 2 252 1.9E-46 T 28-03-2018 CU254_RS42050 ee138d92a014c19186a9c3c8e1ea824f 283 PIRSF PIRSF015582 2 280 2.0E-71 T 28-03-2018 IPR011206 Citrate lyase beta subunit-like CU254_RS21470 9036774692d9db0c6d286efc43526902 136 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 4 81 4.2E-18 T 28-03-2018 IPR003849 Preprotein translocase YajC CU254_RS21470 9036774692d9db0c6d286efc43526902 136 SMART SM01323 2 81 2.2E-23 T 28-03-2018 IPR003849 Preprotein translocase YajC CU254_RS21470 9036774692d9db0c6d286efc43526902 136 Pfam PF02699 Preprotein translocase subunit 5 78 2.0E-20 T 28-03-2018 IPR003849 Preprotein translocase YajC CU254_RS27735 40516a63cd78bd521e5b9f6486f00944 605 SUPERFAMILY SSF54427 15 124 4.18E-10 T 28-03-2018 IPR032710 NTF2-like domain CU254_RS27735 40516a63cd78bd521e5b9f6486f00944 605 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 338 363 5.9E-8 T 28-03-2018 CU254_RS27735 40516a63cd78bd521e5b9f6486f00944 605 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 173 195 5.9E-8 T 28-03-2018 CU254_RS27735 40516a63cd78bd521e5b9f6486f00944 605 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 297 306 5.9E-8 T 28-03-2018 CU254_RS27735 40516a63cd78bd521e5b9f6486f00944 605 Gene3D G3DSA:3.50.50.60 323 508 1.8E-23 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS27735 40516a63cd78bd521e5b9f6486f00944 605 SUPERFAMILY SSF51905 323 511 3.31E-8 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS27735 40516a63cd78bd521e5b9f6486f00944 605 Gene3D G3DSA:3.10.450.50 6 155 5.5E-11 T 28-03-2018 CU254_RS27735 40516a63cd78bd521e5b9f6486f00944 605 SUPERFAMILY SSF51905 174 371 1.46E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS27735 40516a63cd78bd521e5b9f6486f00944 605 Gene3D G3DSA:3.50.50.60 171 322 1.4E-28 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS27735 40516a63cd78bd521e5b9f6486f00944 605 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 175 370 3.2E-22 T 28-03-2018 CU254_RS40975 1c3962dfb5a33cfa494d480a9f65c572 256 Gene3D G3DSA:3.60.130.10 11 244 1.9E-32 T 28-03-2018 CU254_RS40975 1c3962dfb5a33cfa494d480a9f65c572 256 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 23 235 1.3E-24 T 28-03-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 CU254_RS40975 1c3962dfb5a33cfa494d480a9f65c572 256 SUPERFAMILY SSF51197 23 239 2.11E-32 T 28-03-2018 CU254_RS06030 eacc517272a9d6b385f361517b6257af 244 Pfam PF12698 ABC-2 family transporter protein 56 203 2.3E-12 T 28-03-2018 CU254_RS06030 eacc517272a9d6b385f361517b6257af 244 PIRSF PIRSF006648 2 239 8.2E-14 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CU254_RS00745 6b61ad7e583bfd0878db70e168627d68 283 Pfam PF04672 S-adenosyl methyltransferase 10 266 4.2E-76 T 28-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CU254_RS00745 6b61ad7e583bfd0878db70e168627d68 283 PIRSF PIRSF017393 2 283 9.4E-79 T 28-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CU254_RS00745 6b61ad7e583bfd0878db70e168627d68 283 Gene3D G3DSA:3.40.50.150 2 283 5.4E-45 T 28-03-2018 CU254_RS00745 6b61ad7e583bfd0878db70e168627d68 283 SUPERFAMILY SSF53335 12 256 2.28E-42 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS33605 2b85903131a4d023a42f04b8aec6e674 266 SUPERFAMILY SSF53955 105 260 2.67E-14 T 28-03-2018 IPR023346 Lysozyme-like domain CU254_RS33605 2b85903131a4d023a42f04b8aec6e674 266 Gene3D G3DSA:1.10.530.10 88 266 1.0E-19 T 28-03-2018 CU254_RS21210 d5d84423e011c0d91701eb3bfbbef5a1 432 ProSitePatterns PS00216 Sugar transport proteins signature 1. 297 314 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CU254_RS21210 d5d84423e011c0d91701eb3bfbbef5a1 432 Gene3D G3DSA:1.20.1250.20 6 218 9.9E-24 T 28-03-2018 CU254_RS21210 d5d84423e011c0d91701eb3bfbbef5a1 432 Pfam PF00083 Sugar (and other) transporter 16 219 5.1E-23 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CU254_RS21210 d5d84423e011c0d91701eb3bfbbef5a1 432 Pfam PF07690 Major Facilitator Superfamily 279 425 9.3E-10 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS21210 d5d84423e011c0d91701eb3bfbbef5a1 432 SUPERFAMILY SSF103473 10 425 2.49E-63 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS21210 d5d84423e011c0d91701eb3bfbbef5a1 432 Gene3D G3DSA:1.20.1250.20 227 425 1.0E-21 T 28-03-2018 CU254_RS13140 1eed9c49e172a5b1d1d0ab4bb1606d91 294 SUPERFAMILY SSF51679 5 292 1.16E-50 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS13140 1eed9c49e172a5b1d1d0ab4bb1606d91 294 TIGRFAM TIGR03854 F420_MSMEG_3544: probable F420-dependent oxidoreductase, MSMEG_3544 family 5 294 3.6E-120 T 28-03-2018 IPR022402 F420-dependent oxidoreductase-predicted, MSMEG3544 CU254_RS13140 1eed9c49e172a5b1d1d0ab4bb1606d91 294 Pfam PF00296 Luciferase-like monooxygenase 5 233 1.4E-39 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS13140 1eed9c49e172a5b1d1d0ab4bb1606d91 294 Gene3D G3DSA:3.20.20.30 2 293 1.5E-56 T 28-03-2018 CU254_RS19715 2d9aa3a0b8d4a81f50257c7ec5e52e1b 530 Gene3D G3DSA:3.10.105.10 301 489 2.2E-39 T 28-03-2018 CU254_RS19715 2d9aa3a0b8d4a81f50257c7ec5e52e1b 530 SUPERFAMILY SSF53850 48 522 1.14E-116 T 28-03-2018 CU254_RS19715 2d9aa3a0b8d4a81f50257c7ec5e52e1b 530 Gene3D G3DSA:3.40.190.10 174 300 3.7E-33 T 28-03-2018 CU254_RS19715 2d9aa3a0b8d4a81f50257c7ec5e52e1b 530 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 98 417 2.3E-77 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CU254_RS19715 2d9aa3a0b8d4a81f50257c7ec5e52e1b 530 PIRSF PIRSF002741 8 521 2.9E-78 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CU254_RS19715 2d9aa3a0b8d4a81f50257c7ec5e52e1b 530 Gene3D G3DSA:3.90.76.10 71 173 4.1E-26 T 28-03-2018 CU254_RS13585 da03a1585fb42d014a5eab9ebfc235a6 384 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 340 359 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CU254_RS13585 da03a1585fb42d014a5eab9ebfc235a6 384 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 120 7.2E-30 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS13585 da03a1585fb42d014a5eab9ebfc235a6 384 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 124 220 7.2E-25 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CU254_RS13585 da03a1585fb42d014a5eab9ebfc235a6 384 Gene3D G3DSA:2.40.110.10 123 219 1.9E-34 T 28-03-2018 CU254_RS13585 da03a1585fb42d014a5eab9ebfc235a6 384 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 126 138 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CU254_RS13585 da03a1585fb42d014a5eab9ebfc235a6 384 Gene3D G3DSA:1.20.140.10 220 384 5.7E-63 T 28-03-2018 CU254_RS13585 da03a1585fb42d014a5eab9ebfc235a6 384 PIRSF PIRSF016578 5 383 7.3E-22 T 28-03-2018 CU254_RS13585 da03a1585fb42d014a5eab9ebfc235a6 384 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 232 382 4.0E-50 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS13585 da03a1585fb42d014a5eab9ebfc235a6 384 SUPERFAMILY SSF47203 230 383 3.54E-59 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS13585 da03a1585fb42d014a5eab9ebfc235a6 384 Gene3D G3DSA:1.10.540.10 1 121 8.3E-33 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS13585 da03a1585fb42d014a5eab9ebfc235a6 384 SUPERFAMILY SSF56645 7 244 3.14E-75 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS04735 a01657fe5dcbaa4687bbdadf2a8b3b3d 474 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 7 473 7.4E-203 T 28-03-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CU254_RS04735 a01657fe5dcbaa4687bbdadf2a8b3b3d 474 ProSitePatterns PS00180 Glutamine synthetase signature 1. 52 70 - T 28-03-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 CU254_RS04735 a01657fe5dcbaa4687bbdadf2a8b3b3d 474 SUPERFAMILY SSF55931 105 473 1.18E-137 T 28-03-2018 CU254_RS04735 a01657fe5dcbaa4687bbdadf2a8b3b3d 474 Pfam PF00120 Glutamine synthetase, catalytic domain 105 471 2.4E-134 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CU254_RS04735 a01657fe5dcbaa4687bbdadf2a8b3b3d 474 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 390 402 - T 28-03-2018 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CU254_RS04735 a01657fe5dcbaa4687bbdadf2a8b3b3d 474 Gene3D G3DSA:3.30.590.10 107 460 1.3E-123 T 28-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CU254_RS04735 a01657fe5dcbaa4687bbdadf2a8b3b3d 474 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 17 97 4.6E-26 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CU254_RS04735 a01657fe5dcbaa4687bbdadf2a8b3b3d 474 SUPERFAMILY SSF54368 4 102 1.44E-31 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CU254_RS04735 a01657fe5dcbaa4687bbdadf2a8b3b3d 474 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 261 276 - T 28-03-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 CU254_RS04735 a01657fe5dcbaa4687bbdadf2a8b3b3d 474 Gene3D G3DSA:3.10.20.70 4 106 4.3E-27 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CU254_RS04735 a01657fe5dcbaa4687bbdadf2a8b3b3d 474 SMART SM01230 104 383 5.3E-147 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CU254_RS08575 ce2d4b32b340e9aaf6a8b78ac8f27230 305 Pfam PF00005 ABC transporter 21 161 3.2E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS08575 ce2d4b32b340e9aaf6a8b78ac8f27230 305 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS08575 ce2d4b32b340e9aaf6a8b78ac8f27230 305 SMART SM00382 30 209 2.7E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS08575 ce2d4b32b340e9aaf6a8b78ac8f27230 305 Gene3D G3DSA:3.40.50.300 2 286 5.0E-64 T 28-03-2018 CU254_RS08575 ce2d4b32b340e9aaf6a8b78ac8f27230 305 SUPERFAMILY SSF52540 4 222 2.24E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS08575 ce2d4b32b340e9aaf6a8b78ac8f27230 305 Pfam PF13732 Domain of unknown function (DUF4162) 215 297 1.5E-9 T 28-03-2018 IPR025302 Domain of unknown function DUF4162 CU254_RS02650 df9c54e2ece1095111af0e01cfd7a15e 195 Pfam PF00805 Pentapeptide repeats (8 copies) 123 160 6.7E-10 T 28-03-2018 IPR001646 Pentapeptide repeat CU254_RS02650 df9c54e2ece1095111af0e01cfd7a15e 195 Gene3D G3DSA:2.160.20.80 2 99 2.7E-15 T 28-03-2018 CU254_RS02650 df9c54e2ece1095111af0e01cfd7a15e 195 SUPERFAMILY SSF141571 19 193 4.12E-39 T 28-03-2018 CU254_RS02650 df9c54e2ece1095111af0e01cfd7a15e 195 Gene3D G3DSA:2.160.10.20 100 182 6.5E-19 T 28-03-2018 CU254_RS02650 df9c54e2ece1095111af0e01cfd7a15e 195 Pfam PF13599 Pentapeptide repeats (9 copies) 41 117 1.3E-10 T 28-03-2018 IPR001646 Pentapeptide repeat CU254_RS35390 114e37d56d4178ec6c12e7da7c5c65e3 566 Gene3D G3DSA:3.30.200.20 2 109 4.7E-23 T 28-03-2018 CU254_RS35390 114e37d56d4178ec6c12e7da7c5c65e3 566 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 131 143 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CU254_RS35390 114e37d56d4178ec6c12e7da7c5c65e3 566 Gene3D G3DSA:1.10.510.10 110 272 1.3E-35 T 28-03-2018 CU254_RS35390 114e37d56d4178ec6c12e7da7c5c65e3 566 SUPERFAMILY SSF56112 10 266 5.47E-60 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS35390 114e37d56d4178ec6c12e7da7c5c65e3 566 Pfam PF00069 Protein kinase domain 13 259 5.5E-39 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CU254_RS35390 114e37d56d4178ec6c12e7da7c5c65e3 566 SMART SM00220 13 274 1.4E-49 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CU254_RS35390 114e37d56d4178ec6c12e7da7c5c65e3 566 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 19 42 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 CU254_RS10245 8faee0e45d933e6841654f68a64a39c9 150 SMART SM00960 15 105 1.6E-28 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain CU254_RS10245 8faee0e45d933e6841654f68a64a39c9 150 Gene3D G3DSA:3.30.450.30 10 137 3.8E-42 T 28-03-2018 CU254_RS10245 8faee0e45d933e6841654f68a64a39c9 150 SUPERFAMILY SSF103196 9 133 6.28E-33 T 28-03-2018 CU254_RS10245 8faee0e45d933e6841654f68a64a39c9 150 Pfam PF03259 Roadblock/LC7 domain 16 105 4.9E-21 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain CU254_RS38580 717bc405658beb282df35d46a16de4ef 463 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 233 459 5.1E-84 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CU254_RS38580 717bc405658beb282df35d46a16de4ef 463 SUPERFAMILY SSF51230 4 98 5.63E-23 T 28-03-2018 IPR011053 Single hybrid motif CU254_RS38580 717bc405658beb282df35d46a16de4ef 463 Pfam PF00364 Biotin-requiring enzyme 6 77 9.6E-18 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CU254_RS38580 717bc405658beb282df35d46a16de4ef 463 Pfam PF02817 e3 binding domain 172 206 4.5E-11 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CU254_RS38580 717bc405658beb282df35d46a16de4ef 463 Gene3D G3DSA:2.40.50.100 8 65 4.7E-16 T 28-03-2018 CU254_RS38580 717bc405658beb282df35d46a16de4ef 463 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 29 58 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CU254_RS38580 717bc405658beb282df35d46a16de4ef 463 Gene3D G3DSA:3.90.1170.30 66 101 6.1E-5 T 28-03-2018 CU254_RS38580 717bc405658beb282df35d46a16de4ef 463 Gene3D G3DSA:4.10.320.10 152 214 4.6E-16 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CU254_RS38580 717bc405658beb282df35d46a16de4ef 463 Gene3D G3DSA:3.30.559.10 218 462 7.2E-86 T 28-03-2018 CU254_RS38580 717bc405658beb282df35d46a16de4ef 463 SUPERFAMILY SSF52777 227 459 1.56E-83 T 28-03-2018 CU254_RS38580 717bc405658beb282df35d46a16de4ef 463 SUPERFAMILY SSF47005 169 211 2.62E-8 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CU254_RS36105 92942a7f432a05ddaf6dcf152bdbee4d 251 Gene3D G3DSA:1.10.10.10 1 67 1.5E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS36105 92942a7f432a05ddaf6dcf152bdbee4d 251 SMART SM00420 6 58 4.8E-9 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CU254_RS36105 92942a7f432a05ddaf6dcf152bdbee4d 251 Gene3D G3DSA:3.40.50.1360 68 242 4.2E-37 T 28-03-2018 CU254_RS36105 92942a7f432a05ddaf6dcf152bdbee4d 251 SMART SM01134 71 231 8.1E-58 T 28-03-2018 CU254_RS36105 92942a7f432a05ddaf6dcf152bdbee4d 251 SUPERFAMILY SSF100950 75 230 1.3E-27 T 28-03-2018 CU254_RS36105 92942a7f432a05ddaf6dcf152bdbee4d 251 Pfam PF00455 DeoR C terminal sensor domain 74 230 3.5E-43 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain CU254_RS36105 92942a7f432a05ddaf6dcf152bdbee4d 251 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 7.0E-7 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CU254_RS36105 92942a7f432a05ddaf6dcf152bdbee4d 251 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 7.0E-7 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CU254_RS36105 92942a7f432a05ddaf6dcf152bdbee4d 251 Pfam PF08220 DeoR-like helix-turn-helix domain 6 57 5.4E-13 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CU254_RS36105 92942a7f432a05ddaf6dcf152bdbee4d 251 SUPERFAMILY SSF46785 6 58 1.99E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS00020 9d93ac5919909be7d161c5e2fe5303f3 853 SUPERFAMILY SSF48452 98 276 1.49E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS00020 9d93ac5919909be7d161c5e2fe5303f3 853 SMART SM00028 175 208 100.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS00020 9d93ac5919909be7d161c5e2fe5303f3 853 SMART SM00028 135 168 0.15 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS00020 9d93ac5919909be7d161c5e2fe5303f3 853 Pfam PF12770 CHAT domain 620 837 9.3E-25 T 28-03-2018 IPR024983 CHAT domain CU254_RS00020 9d93ac5919909be7d161c5e2fe5303f3 853 Gene3D G3DSA:1.25.40.10 2 339 2.8E-21 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS00020 9d93ac5919909be7d161c5e2fe5303f3 853 Pfam PF13424 Tetratricopeptide repeat 137 204 1.9E-7 T 28-03-2018 CU254_RS00020 9d93ac5919909be7d161c5e2fe5303f3 853 Gene3D G3DSA:3.40.50.1460 672 840 9.6E-10 T 28-03-2018 CU254_RS25605 2c2f0daafd53e2426c439f47723a5890 604 SUPERFAMILY SSF51658 6 270 4.98E-72 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CU254_RS25605 2c2f0daafd53e2426c439f47723a5890 604 Gene3D G3DSA:3.10.180.10 293 410 2.7E-5 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS25605 2c2f0daafd53e2426c439f47723a5890 604 SUPERFAMILY SSF54593 294 591 5.07E-37 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS25605 2c2f0daafd53e2426c439f47723a5890 604 Gene3D G3DSA:3.10.180.10 412 602 8.4E-29 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS25605 2c2f0daafd53e2426c439f47723a5890 604 Pfam PF01261 Xylose isomerase-like TIM barrel 22 221 1.4E-35 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CU254_RS25605 2c2f0daafd53e2426c439f47723a5890 604 Gene3D G3DSA:3.20.20.150 2 270 1.6E-56 T 28-03-2018 CU254_RS25605 2c2f0daafd53e2426c439f47723a5890 604 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 416 524 2.6E-5 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CU254_RS20995 2466f4a837c5551495cb2b76be7a63a8 218 SUPERFAMILY SSF52218 1 204 7.68E-29 T 28-03-2018 IPR029039 Flavoprotein-like domain CU254_RS20995 2466f4a837c5551495cb2b76be7a63a8 218 Gene3D G3DSA:3.40.50.360 1 218 7.0E-31 T 28-03-2018 IPR029039 Flavoprotein-like domain CU254_RS20995 2466f4a837c5551495cb2b76be7a63a8 218 Pfam PF02525 Flavodoxin-like fold 1 181 1.4E-25 T 28-03-2018 IPR003680 Flavodoxin-like fold CU254_RS16840 ebc16612701da50fc1644239b136ef87 312 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 307 2.1E-34 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS16840 ebc16612701da50fc1644239b136ef87 312 SUPERFAMILY SSF161098 90 297 3.66E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS16840 ebc16612701da50fc1644239b136ef87 312 Gene3D G3DSA:1.10.3720.10 1 303 5.1E-41 T 28-03-2018 CU254_RS14085 f1173701f23f038dadd0a8eace3af4e5 530 SUPERFAMILY SSF51338 5 57 3.39E-14 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS14085 f1173701f23f038dadd0a8eace3af4e5 530 SUPERFAMILY SSF51338 490 529 3.39E-14 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS14085 f1173701f23f038dadd0a8eace3af4e5 530 Pfam PF07969 Amidohydrolase family 46 530 3.7E-82 T 28-03-2018 IPR013108 Amidohydrolase 3 CU254_RS14085 f1173701f23f038dadd0a8eace3af4e5 530 Gene3D G3DSA:2.30.40.10 2 94 2.4E-16 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS14085 f1173701f23f038dadd0a8eace3af4e5 530 Gene3D G3DSA:3.20.20.140 177 488 3.5E-54 T 28-03-2018 CU254_RS14085 f1173701f23f038dadd0a8eace3af4e5 530 SUPERFAMILY SSF51556 190 490 4.09E-43 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS14085 f1173701f23f038dadd0a8eace3af4e5 530 SUPERFAMILY SSF51556 56 113 4.09E-43 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS17945 b95bee32963168d2bfae7c198414cf60 323 PIRSF PIRSF018005 1 321 5.0E-129 T 28-03-2018 IPR017804 Methyltransferase EgtD-like CU254_RS17945 b95bee32963168d2bfae7c198414cf60 323 Gene3D G3DSA:3.40.50.150 9 320 1.9E-21 T 28-03-2018 CU254_RS17945 b95bee32963168d2bfae7c198414cf60 323 TIGRFAM TIGR03438 egtD_ergothio: dimethylhistidine N-methyltransferase 17 317 2.1E-115 T 28-03-2018 IPR035094 Histidine N-alpha-methyltransferase KEGG: 00340+2.1.1.44|MetaCyc: PWY-7255|MetaCyc: PWY-7550 CU254_RS17945 b95bee32963168d2bfae7c198414cf60 323 Hamap MF_02037 Histidine N-alpha-methyltransferase [egtD]. 4 320 55.721 T 28-03-2018 IPR032888 Histidine N-alpha-methyltransferase, Actinobacteria-type GO:0008276|GO:0052699 KEGG: 00340+2.1.1.44|MetaCyc: PWY-7255|MetaCyc: PWY-7550 CU254_RS17945 b95bee32963168d2bfae7c198414cf60 323 Pfam PF10017 Histidine-specific methyltransferase, SAM-dependent 17 319 4.3E-114 T 28-03-2018 IPR019257 Histidine-specific methyltransferase, SAM-dependent CU254_RS17945 b95bee32963168d2bfae7c198414cf60 323 SUPERFAMILY SSF53335 34 193 8.61E-12 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS17945 b95bee32963168d2bfae7c198414cf60 323 SUPERFAMILY SSF53335 283 312 8.61E-12 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS17945 b95bee32963168d2bfae7c198414cf60 323 SUPERFAMILY SSF53335 230 256 8.61E-12 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS29770 dbf25c0b290077d2030fdc962117e67c 312 Pfam PF07728 AAA domain (dynein-related subfamily) 44 181 1.2E-26 T 28-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 CU254_RS29770 dbf25c0b290077d2030fdc962117e67c 312 Gene3D G3DSA:3.40.50.300 11 216 5.6E-27 T 28-03-2018 CU254_RS29770 dbf25c0b290077d2030fdc962117e67c 312 SUPERFAMILY SSF52540 15 251 9.0E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS29770 dbf25c0b290077d2030fdc962117e67c 312 Gene3D G3DSA:1.10.8.80 217 292 7.8E-8 T 28-03-2018 CU254_RS29770 dbf25c0b290077d2030fdc962117e67c 312 PIRSF PIRSF002849 15 212 1.7E-24 T 28-03-2018 CU254_RS29770 dbf25c0b290077d2030fdc962117e67c 312 PIRSF PIRSF002849 203 296 4.4E-8 T 28-03-2018 CU254_RS29770 dbf25c0b290077d2030fdc962117e67c 312 SMART SM00382 41 192 9.0E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS29770 dbf25c0b290077d2030fdc962117e67c 312 PRINTS PR00819 CbxX/CfqX superfamily signature 44 59 1.4E-5 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CU254_RS29770 dbf25c0b290077d2030fdc962117e67c 312 PRINTS PR00819 CbxX/CfqX superfamily signature 229 241 1.4E-5 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CU254_RS29770 dbf25c0b290077d2030fdc962117e67c 312 PRINTS PR00819 CbxX/CfqX superfamily signature 127 139 1.4E-5 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CU254_RS18885 1c383f08df0d8577eaf7bc343af43496 136 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 123 9.3E-7 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CU254_RS18885 1c383f08df0d8577eaf7bc343af43496 136 SUPERFAMILY SSF54593 1 126 2.75E-23 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS18885 1c383f08df0d8577eaf7bc343af43496 136 Gene3D G3DSA:3.10.180.10 1 134 3.4E-19 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS19260 9f1c28ffadcddbdf6ea5bc86ef466558 120 Gene3D G3DSA:3.10.180.10 4 117 6.1E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS19260 9f1c28ffadcddbdf6ea5bc86ef466558 120 SUPERFAMILY SSF54593 6 119 1.79E-18 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS36100 591dc15ff9366f0e4ffa61076f1d08d3 121 Gene3D G3DSA:3.40.50.10400 1 116 1.6E-23 T 28-03-2018 IPR027269 Hypothetical PA1492 domain CU254_RS36100 591dc15ff9366f0e4ffa61076f1d08d3 121 SUPERFAMILY SSF52309 2 109 2.7E-5 T 28-03-2018 CU254_RS06010 ed7c310b3517d11f83b63d32a7b26790 255 PIRSF PIRSF039085 2 255 7.3E-116 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CU254_RS06010 ed7c310b3517d11f83b63d32a7b26790 255 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS06010 ed7c310b3517d11f83b63d32a7b26790 255 SMART SM00382 30 227 1.7E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS06010 ed7c310b3517d11f83b63d32a7b26790 255 SUPERFAMILY SSF52540 5 249 1.2E-77 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS06010 ed7c310b3517d11f83b63d32a7b26790 255 Pfam PF00005 ABC transporter 21 179 4.5E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS06010 ed7c310b3517d11f83b63d32a7b26790 255 Gene3D G3DSA:3.40.50.300 2 255 1.3E-71 T 28-03-2018 CU254_RS11635 ae7259bacc8fc77b4c8a9c2e6ccbf558 329 Pfam PF10298 WhiA N-terminal LAGLIDADG-like domain 22 105 4.0E-23 T 28-03-2018 IPR018478 Sporulation transcription regulator WhiA, N-terminal domain CU254_RS11635 ae7259bacc8fc77b4c8a9c2e6ccbf558 329 Hamap MF_01420 Putative sporulation transcription regulator WhiA [whiA]. 3 307 28.531 T 28-03-2018 IPR003802 Sporulation regulator WhiA GO:0043937 CU254_RS11635 ae7259bacc8fc77b4c8a9c2e6ccbf558 329 Gene3D G3DSA:3.10.28.10 116 225 0.09 T 28-03-2018 IPR027434 Homing endonuclease GO:0004519 CU254_RS11635 ae7259bacc8fc77b4c8a9c2e6ccbf558 329 Pfam PF14527 WhiA LAGLIDADG-like domain 128 219 2.0E-24 T 28-03-2018 CU254_RS11635 ae7259bacc8fc77b4c8a9c2e6ccbf558 329 TIGRFAM TIGR00647 DNA_bind_WhiA: DNA-binding protein WhiA 4 305 1.6E-102 T 28-03-2018 IPR033981 Sporulation regulator WhiA-like CU254_RS11635 ae7259bacc8fc77b4c8a9c2e6ccbf558 329 Pfam PF02650 WhiA C-terminal HTH domain 222 304 3.9E-19 T 28-03-2018 IPR023054 Sporulation regulator WhiA, C-terminal CU254_RS18225 b79d6a9a679abcdb3a3f527068404f30 500 Gene3D G3DSA:1.10.287.1170 412 465 0.0018 T 28-03-2018 CU254_RS18225 b79d6a9a679abcdb3a3f527068404f30 500 Pfam PF03136 Pup-ligase protein 3 454 1.8E-180 T 28-03-2018 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 CU254_RS18225 b79d6a9a679abcdb3a3f527068404f30 500 PIRSF PIRSF018077 8 496 1.2E-201 T 28-03-2018 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 CU254_RS18225 b79d6a9a679abcdb3a3f527068404f30 500 TIGRFAM TIGR03688 pupylate_PafA2: proteasome accessory factor PafA2 2 485 3.7E-231 T 28-03-2018 IPR022366 Pup deamidase GO:0008233|GO:0016811 CU254_RS36130 05a09fe074d145ff577eee43d986adb5 163 Gene3D G3DSA:3.40.1050.10 1 163 1.5E-29 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CU254_RS36130 05a09fe074d145ff577eee43d986adb5 163 SUPERFAMILY SSF53056 24 162 3.66E-31 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CU254_RS36130 05a09fe074d145ff577eee43d986adb5 163 Pfam PF00484 Carbonic anhydrase 33 130 4.8E-12 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CU254_RS36130 05a09fe074d145ff577eee43d986adb5 163 SMART SM00947 24 163 2.6E-22 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CU254_RS12790 11cc7e997f597cf996b4fe00af795d10 277 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 32 213 0.0023 T 28-03-2018 CU254_RS12790 11cc7e997f597cf996b4fe00af795d10 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 170 5.1E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS12790 11cc7e997f597cf996b4fe00af795d10 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 238 258 5.1E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS12790 11cc7e997f597cf996b4fe00af795d10 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 33 50 5.1E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS12790 11cc7e997f597cf996b4fe00af795d10 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 107 118 5.1E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS12790 11cc7e997f597cf996b4fe00af795d10 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 201 5.1E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS12790 11cc7e997f597cf996b4fe00af795d10 277 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 203 220 5.1E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS12790 11cc7e997f597cf996b4fe00af795d10 277 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 182 201 1.1E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS12790 11cc7e997f597cf996b4fe00af795d10 277 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 168 1.1E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS12790 11cc7e997f597cf996b4fe00af795d10 277 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 107 118 1.1E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS12790 11cc7e997f597cf996b4fe00af795d10 277 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 169 197 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS12790 11cc7e997f597cf996b4fe00af795d10 277 Gene3D G3DSA:3.40.50.720 72 277 2.6E-63 T 28-03-2018 CU254_RS12790 11cc7e997f597cf996b4fe00af795d10 277 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 38 275 1.9E-67 T 28-03-2018 CU254_RS12790 11cc7e997f597cf996b4fe00af795d10 277 SUPERFAMILY SSF51735 29 276 6.75E-80 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS12790 11cc7e997f597cf996b4fe00af795d10 277 Gene3D G3DSA:3.40.50.10090 24 71 6.7E-11 T 28-03-2018 CU254_RS11330 f2e33f2a6d7d7b3091c787cc103fc178 166 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 20 157 22.458 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CU254_RS11330 f2e33f2a6d7d7b3091c787cc103fc178 166 SMART SM00732 20 122 1.8E-23 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 CU254_RS11330 f2e33f2a6d7d7b3091c787cc103fc178 166 SUPERFAMILY SSF53098 20 155 1.05E-33 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS11330 f2e33f2a6d7d7b3091c787cc103fc178 166 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 23 154 5.7E-28 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CU254_RS11330 f2e33f2a6d7d7b3091c787cc103fc178 166 Gene3D G3DSA:3.30.420.140 18 166 3.0E-43 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 CU254_RS11330 f2e33f2a6d7d7b3091c787cc103fc178 166 Pfam PF03652 Holliday junction resolvase 21 154 1.1E-41 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CU254_RS12220 10597d5b354104cc4664ec3ad96f82ab 262 Pfam PF12697 Alpha/beta hydrolase family 19 247 8.8E-20 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS12220 10597d5b354104cc4664ec3ad96f82ab 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 200 214 5.3E-13 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS12220 10597d5b354104cc4664ec3ad96f82ab 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 100 113 5.3E-13 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS12220 10597d5b354104cc4664ec3ad96f82ab 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 42 57 5.3E-13 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS12220 10597d5b354104cc4664ec3ad96f82ab 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 86 99 5.3E-13 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS12220 10597d5b354104cc4664ec3ad96f82ab 262 Gene3D G3DSA:3.40.50.1820 2 257 1.6E-46 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS12220 10597d5b354104cc4664ec3ad96f82ab 262 SUPERFAMILY SSF53474 10 255 2.68E-59 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS09750 f0544e7d89195fa7763592939d18fd21 222 TIGRFAM TIGR00498 lexA: repressor LexA 12 221 4.3E-77 T 28-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 CU254_RS09750 f0544e7d89195fa7763592939d18fd21 222 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 177 189 1.1E-10 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CU254_RS09750 f0544e7d89195fa7763592939d18fd21 222 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 138 148 1.1E-10 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CU254_RS09750 f0544e7d89195fa7763592939d18fd21 222 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 149 160 1.1E-10 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CU254_RS09750 f0544e7d89195fa7763592939d18fd21 222 SUPERFAMILY SSF46785 13 79 6.34E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS09750 f0544e7d89195fa7763592939d18fd21 222 SUPERFAMILY SSF51306 102 220 8.89E-35 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CU254_RS09750 f0544e7d89195fa7763592939d18fd21 222 Pfam PF00717 Peptidase S24-like 142 206 7.0E-16 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CU254_RS09750 f0544e7d89195fa7763592939d18fd21 222 Gene3D G3DSA:1.10.10.10 13 78 8.3E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS09750 f0544e7d89195fa7763592939d18fd21 222 Hamap MF_00015 LexA repressor [lexA]. 13 222 33.058 T 28-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 CU254_RS09750 f0544e7d89195fa7763592939d18fd21 222 Gene3D G3DSA:2.10.109.10 107 222 4.5E-27 T 28-03-2018 CU254_RS09750 f0544e7d89195fa7763592939d18fd21 222 Pfam PF01726 LexA DNA binding domain 12 75 3.9E-26 T 28-03-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 CU254_RS38820 6804a9f129495fded411473e698633cf 231 Gene3D G3DSA:3.40.50.300 8 228 6.6E-59 T 28-03-2018 CU254_RS38820 6804a9f129495fded411473e698633cf 231 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS38820 6804a9f129495fded411473e698633cf 231 SMART SM00382 36 224 1.3E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS38820 6804a9f129495fded411473e698633cf 231 SUPERFAMILY SSF52540 12 226 1.33E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS38820 6804a9f129495fded411473e698633cf 231 Pfam PF00005 ABC transporter 28 175 9.4E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS08880 91498a3a71b07822575ef5e9e3eb68c2 137 SUPERFAMILY SSF52172 7 129 4.41E-7 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS08880 91498a3a71b07822575ef5e9e3eb68c2 137 Gene3D G3DSA:3.40.50.2300 2 132 1.4E-9 T 28-03-2018 CU254_RS37470 4afaef3454f85bdf0ccf1a8569d22532 144 PIRSF PIRSF030042 13 143 5.9E-11 T 28-03-2018 IPR016942 Uncharacterised conserved protein UCP030042 CU254_RS37470 4afaef3454f85bdf0ccf1a8569d22532 144 Pfam PF14340 Domain of unknown function (DUF4395) 7 136 3.1E-46 T 28-03-2018 IPR025508 Domain of unknown function DUF4395 CU254_RS15300 ab680129bd5d190cedd2baa5d564378b 494 Gene3D G3DSA:3.90.1300.10 1 454 1.0E-129 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS15300 ab680129bd5d190cedd2baa5d564378b 494 Pfam PF01425 Amidase 23 429 1.1E-97 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS15300 ab680129bd5d190cedd2baa5d564378b 494 ProSitePatterns PS00571 Amidases signature. 150 181 - T 28-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CU254_RS15300 ab680129bd5d190cedd2baa5d564378b 494 SUPERFAMILY SSF75304 3 446 5.36E-123 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS18045 474d12f8dab270fb2990fbab5a2f345a 462 SMART SM00388 237 299 2.4E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS18045 474d12f8dab270fb2990fbab5a2f345a 462 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 352 458 3.7E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS18045 474d12f8dab270fb2990fbab5a2f345a 462 SUPERFAMILY SSF55874 309 458 1.2E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS18045 474d12f8dab270fb2990fbab5a2f345a 462 Gene3D G3DSA:1.10.287.130 227 294 5.5E-11 T 28-03-2018 CU254_RS18045 474d12f8dab270fb2990fbab5a2f345a 462 PRINTS PR00344 Bacterial sensor protein C-terminal signature 420 438 3.1E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS18045 474d12f8dab270fb2990fbab5a2f345a 462 PRINTS PR00344 Bacterial sensor protein C-terminal signature 444 457 3.1E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS18045 474d12f8dab270fb2990fbab5a2f345a 462 PRINTS PR00344 Bacterial sensor protein C-terminal signature 387 401 3.1E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS18045 474d12f8dab270fb2990fbab5a2f345a 462 Pfam PF00672 HAMP domain 184 232 7.3E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS18045 474d12f8dab270fb2990fbab5a2f345a 462 Pfam PF00512 His Kinase A (phospho-acceptor) domain 238 298 5.5E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS18045 474d12f8dab270fb2990fbab5a2f345a 462 SMART SM00387 350 460 2.2E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS18045 474d12f8dab270fb2990fbab5a2f345a 462 Gene3D G3DSA:3.30.565.10 307 462 1.3E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS18045 474d12f8dab270fb2990fbab5a2f345a 462 SMART SM00304 184 236 1.9E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS18045 474d12f8dab270fb2990fbab5a2f345a 462 SUPERFAMILY SSF47384 220 298 8.24E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS18045 474d12f8dab270fb2990fbab5a2f345a 462 Gene3D G3DSA:3.30.450.20 24 157 2.6E-4 T 28-03-2018 CU254_RS13015 ef3c9ca5f2c33586b8d8db05cf6325ed 434 Gene3D G3DSA:1.20.1250.20 224 427 1.5E-19 T 28-03-2018 CU254_RS13015 ef3c9ca5f2c33586b8d8db05cf6325ed 434 Pfam PF00083 Sugar (and other) transporter 265 423 1.9E-7 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CU254_RS13015 ef3c9ca5f2c33586b8d8db05cf6325ed 434 Pfam PF00083 Sugar (and other) transporter 15 230 3.5E-25 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CU254_RS13015 ef3c9ca5f2c33586b8d8db05cf6325ed 434 Gene3D G3DSA:1.20.1250.20 9 223 1.9E-24 T 28-03-2018 CU254_RS13015 ef3c9ca5f2c33586b8d8db05cf6325ed 434 SUPERFAMILY SSF103473 11 421 3.53E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS20135 e46b40718677fccc743403a23a96f849 323 Gene3D G3DSA:3.90.870.10 2 203 3.1E-77 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CU254_RS20135 e46b40718677fccc743403a23a96f849 323 Pfam PF01300 Telomere recombination 14 189 5.6E-57 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 CU254_RS20135 e46b40718677fccc743403a23a96f849 323 PIRSF PIRSF004930 2 323 7.1E-109 T 28-03-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 CU254_RS20135 e46b40718677fccc743403a23a96f849 323 Pfam PF03481 Putative GTP-binding controlling metal-binding 192 320 2.0E-22 T 28-03-2018 IPR005145 Putative GTP-binding controlling metal-binding domain CU254_RS20135 e46b40718677fccc743403a23a96f849 323 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 7 200 2.0E-56 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 CU254_RS20135 e46b40718677fccc743403a23a96f849 323 SUPERFAMILY SSF55821 8 201 1.28E-63 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CU254_RS01390 717bf5f82d93af6fe8327f141fd240af 99 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 6 93 4.9E-24 T 28-03-2018 CU254_RS01390 717bf5f82d93af6fe8327f141fd240af 99 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 1 99 20.254 T 28-03-2018 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 CU254_RS02715 bfccec6dceae7cbbf3809cc5b81ab42b 199 Gene3D G3DSA:3.40.50.150 1 194 2.2E-32 T 28-03-2018 CU254_RS02715 bfccec6dceae7cbbf3809cc5b81ab42b 199 Pfam PF13649 Methyltransferase domain 37 129 7.0E-18 T 28-03-2018 CU254_RS02715 bfccec6dceae7cbbf3809cc5b81ab42b 199 SUPERFAMILY SSF53335 3 183 2.56E-35 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS25125 14d3c10e28666a4a53938b4bb9ee4c40 89 Pfam PF02467 Transcription factor WhiB 8 76 5.0E-24 T 28-03-2018 IPR034768 WhiB-like iron-sulfur binding domain CU254_RS25125 14d3c10e28666a4a53938b4bb9ee4c40 89 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 81 16.395 T 28-03-2018 IPR003482 Transcription factor WhiB CU254_RS04045 d64607a2a2404d5b4b90843386e2e0ec 202 SUPERFAMILY SSF56436 1 201 4.47E-49 T 28-03-2018 IPR016187 C-type lectin fold CU254_RS04045 d64607a2a2404d5b4b90843386e2e0ec 202 Pfam PF03781 Sulfatase-modifying factor enzyme 1 43 200 1.1E-35 T 28-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 CU254_RS04045 d64607a2a2404d5b4b90843386e2e0ec 202 Gene3D G3DSA:3.90.1580.10 1 40 0.073 T 28-03-2018 CU254_RS04045 d64607a2a2404d5b4b90843386e2e0ec 202 Gene3D G3DSA:3.90.1580.10 41 202 6.9E-42 T 28-03-2018 CU254_RS17440 7fef6a4cc6aed8b3b0e1428dad1988dc 400 Gene3D G3DSA:3.40.50.150 49 250 3.2E-33 T 28-03-2018 CU254_RS17440 7fef6a4cc6aed8b3b0e1428dad1988dc 400 Pfam PF08484 C-methyltransferase C-terminal domain 238 395 1.9E-52 T 28-03-2018 IPR013691 C-methyltransferase CU254_RS17440 7fef6a4cc6aed8b3b0e1428dad1988dc 400 SUPERFAMILY SSF53335 71 246 4.6E-25 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS17440 7fef6a4cc6aed8b3b0e1428dad1988dc 400 Pfam PF08421 Putative zinc binding domain 2 58 2.0E-13 T 28-03-2018 IPR013630 Methyltransferase putative zinc binding domain CU254_RS17440 7fef6a4cc6aed8b3b0e1428dad1988dc 400 Pfam PF13489 Methyltransferase domain 91 233 1.3E-18 T 28-03-2018 CU254_RS28650 ec09e7c396784478f8779305b8495eed 290 Gene3D G3DSA:2.40.10.10 167 286 2.0E-37 T 28-03-2018 CU254_RS28650 ec09e7c396784478f8779305b8495eed 290 Gene3D G3DSA:2.40.10.10 70 166 5.1E-33 T 28-03-2018 CU254_RS28650 ec09e7c396784478f8779305b8495eed 290 PRINTS PR00834 HtrA/DegQ protease family signature 109 121 5.5E-29 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CU254_RS28650 ec09e7c396784478f8779305b8495eed 290 PRINTS PR00834 HtrA/DegQ protease family signature 226 243 5.5E-29 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CU254_RS28650 ec09e7c396784478f8779305b8495eed 290 PRINTS PR00834 HtrA/DegQ protease family signature 248 265 5.5E-29 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CU254_RS28650 ec09e7c396784478f8779305b8495eed 290 PRINTS PR00834 HtrA/DegQ protease family signature 130 150 5.5E-29 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CU254_RS28650 ec09e7c396784478f8779305b8495eed 290 Pfam PF13365 Trypsin-like peptidase domain 100 255 4.7E-35 T 28-03-2018 CU254_RS28650 ec09e7c396784478f8779305b8495eed 290 SUPERFAMILY SSF50494 75 287 8.83E-56 T 28-03-2018 IPR009003 Peptidase S1, PA clan CU254_RS27995 918f860168e65d5ef327a8f980cdc5a5 489 Gene3D G3DSA:3.40.190.10 152 283 1.8E-16 T 28-03-2018 CU254_RS27995 918f860168e65d5ef327a8f980cdc5a5 489 PIRSF PIRSF002741 6 381 3.4E-38 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CU254_RS27995 918f860168e65d5ef327a8f980cdc5a5 489 PIRSF PIRSF002741 398 486 0.11 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CU254_RS27995 918f860168e65d5ef327a8f980cdc5a5 489 SUPERFAMILY SSF53850 39 486 9.96E-60 T 28-03-2018 CU254_RS27995 918f860168e65d5ef327a8f980cdc5a5 489 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 75 356 3.4E-38 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CU254_RS27995 918f860168e65d5ef327a8f980cdc5a5 489 Gene3D G3DSA:3.90.76.10 49 151 1.1E-18 T 28-03-2018 CU254_RS27995 918f860168e65d5ef327a8f980cdc5a5 489 Gene3D G3DSA:3.10.105.10 284 459 4.9E-15 T 28-03-2018 CU254_RS19915 3abb37e5f966ab8a9f57a6617658ef37 200 SUPERFAMILY SSF53597 1 42 4.71E-22 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CU254_RS19915 3abb37e5f966ab8a9f57a6617658ef37 200 SUPERFAMILY SSF53597 70 199 4.71E-22 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CU254_RS19915 3abb37e5f966ab8a9f57a6617658ef37 200 Gene3D G3DSA:3.40.430.10 2 196 8.6E-30 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CU254_RS19915 3abb37e5f966ab8a9f57a6617658ef37 200 Pfam PF01872 RibD C-terminal domain 3 186 1.9E-11 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CU254_RS36675 df5c32c1864453b9d52a81ff25e39461 239 Pfam PF00975 Thioesterase domain 20 119 9.6E-15 T 28-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CU254_RS36675 df5c32c1864453b9d52a81ff25e39461 239 SMART SM00824 Thioesterase 23 229 9.2E-7 T 28-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 CU254_RS36675 df5c32c1864453b9d52a81ff25e39461 239 SUPERFAMILY SSF53474 11 229 1.4E-33 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS36675 df5c32c1864453b9d52a81ff25e39461 239 Gene3D G3DSA:3.40.50.1820 2 238 5.2E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS31925 0017e3d57078a5b3b8afb8839589b412 122 SUPERFAMILY SSF54593 3 119 5.09E-21 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS31925 0017e3d57078a5b3b8afb8839589b412 122 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 116 6.5E-7 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CU254_RS31925 0017e3d57078a5b3b8afb8839589b412 122 Gene3D G3DSA:3.10.180.10 4 122 2.2E-17 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS05465 a12a03fe7effed18a1e92dd52e96e488 142 SUPERFAMILY SSF46785 6 135 6.06E-33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS05465 a12a03fe7effed18a1e92dd52e96e488 142 Gene3D G3DSA:1.10.10.10 7 91 1.7E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS05465 a12a03fe7effed18a1e92dd52e96e488 142 Pfam PF01475 Ferric uptake regulator family 15 128 1.7E-19 T 28-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CU254_RS35630 a5a2563351bc261ad20b30240029a59b 1007 Gene3D G3DSA:3.40.1090.10 3 354 1.8E-20 T 28-03-2018 CU254_RS35630 a5a2563351bc261ad20b30240029a59b 1007 TIGRFAM TIGR03607 TIGR03607: patatin-related protein 11 362 1.8E-83 T 28-03-2018 IPR019894 Patatin-related protein CU254_RS35630 a5a2563351bc261ad20b30240029a59b 1007 Pfam PF01734 Patatin-like phospholipase 17 257 1.1E-14 T 28-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 CU254_RS35630 a5a2563351bc261ad20b30240029a59b 1007 SUPERFAMILY SSF52151 13 110 9.42E-14 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CU254_RS35630 a5a2563351bc261ad20b30240029a59b 1007 SUPERFAMILY SSF52151 151 266 9.42E-14 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CU254_RS35630 a5a2563351bc261ad20b30240029a59b 1007 Pfam PF11856 Protein of unknown function (DUF3376) 318 674 1.3E-24 T 28-03-2018 IPR024282 Domain of unknown function DUF3376 CU254_RS09405 e8162b36675124381593d77554ddb53b 463 Pfam PF01474 Class-II DAHP synthetase family 31 458 5.5E-188 T 28-03-2018 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CU254_RS09405 e8162b36675124381593d77554ddb53b 463 TIGRFAM TIGR01358 DAHP_synth_II: 3-deoxy-7-phosphoheptulonate synthase 26 462 3.5E-212 T 28-03-2018 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CU254_RS09405 e8162b36675124381593d77554ddb53b 463 SUPERFAMILY SSF51569 5 462 5.86E-193 T 28-03-2018 CU254_RS09405 e8162b36675124381593d77554ddb53b 463 Gene3D G3DSA:3.20.20.70 259 410 2.2E-5 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS13225 e24ba7a9e04f6ccd69fbdbbcb5c7f8d3 400 Gene3D G3DSA:1.20.1250.20 211 399 4.0E-13 T 28-03-2018 CU254_RS13225 e24ba7a9e04f6ccd69fbdbbcb5c7f8d3 400 SUPERFAMILY SSF103473 14 395 9.16E-37 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS13225 e24ba7a9e04f6ccd69fbdbbcb5c7f8d3 400 Pfam PF07690 Major Facilitator Superfamily 35 356 1.8E-13 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS13225 e24ba7a9e04f6ccd69fbdbbcb5c7f8d3 400 Gene3D G3DSA:1.20.1250.20 18 210 1.5E-15 T 28-03-2018 CU254_RS07040 30309481205340d261828778cbcbbacd 805 Gene3D G3DSA:3.30.870.10 624 803 2.2E-38 T 28-03-2018 CU254_RS07040 30309481205340d261828778cbcbbacd 805 SUPERFAMILY SSF56024 625 800 4.93E-61 T 28-03-2018 CU254_RS07040 30309481205340d261828778cbcbbacd 805 SUPERFAMILY SSF56024 448 621 1.07E-56 T 28-03-2018 CU254_RS07040 30309481205340d261828778cbcbbacd 805 Pfam PF13089 Polyphosphate kinase N-terminal domain 128 234 7.5E-38 T 28-03-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 CU254_RS07040 30309481205340d261828778cbcbbacd 805 Gene3D G3DSA:3.30.1840.10 233 427 3.5E-75 T 28-03-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 CU254_RS07040 30309481205340d261828778cbcbbacd 805 SUPERFAMILY SSF143724 231 432 3.73E-67 T 28-03-2018 CU254_RS07040 30309481205340d261828778cbcbbacd 805 Gene3D G3DSA:1.20.58.310 130 232 8.0E-38 T 28-03-2018 CU254_RS07040 30309481205340d261828778cbcbbacd 805 Pfam PF13090 Polyphosphate kinase C-terminal domain 453 795 2.9E-147 T 28-03-2018 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 CU254_RS07040 30309481205340d261828778cbcbbacd 805 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 127 796 4.7E-252 T 28-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 CU254_RS07040 30309481205340d261828778cbcbbacd 805 Pfam PF02503 Polyphosphate kinase middle domain 246 442 1.1E-70 T 28-03-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 CU254_RS07040 30309481205340d261828778cbcbbacd 805 Hamap MF_00347 Polyphosphate kinase [ppk]. 126 803 29.341 T 28-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 CU254_RS07040 30309481205340d261828778cbcbbacd 805 SUPERFAMILY SSF140356 125 228 1.2E-37 T 28-03-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 CU254_RS07040 30309481205340d261828778cbcbbacd 805 Gene3D G3DSA:3.30.870.10 438 623 1.3E-19 T 28-03-2018 CU254_RS17065 99608039d357165a85377944298de553 354 Pfam PF06032 Protein of unknown function (DUF917) 8 340 6.4E-77 T 28-03-2018 IPR010318 Protein of unknown function DUF917 CU254_RS17065 99608039d357165a85377944298de553 354 Gene3D G3DSA:3.40.1610.10 2 216 5.7E-45 T 28-03-2018 IPR027479 Protein of unknown function DUF917, N-terminal CU254_RS17065 99608039d357165a85377944298de553 354 Gene3D G3DSA:2.40.390.10 217 334 3.0E-27 T 28-03-2018 IPR024071 Protein of unknown function DUF917, C-terminal CU254_RS17065 99608039d357165a85377944298de553 354 SUPERFAMILY SSF160991 3 344 1.83E-81 T 28-03-2018 CU254_RS23475 3557e5d8a5321223844b2d026f7e4caa 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 3.7E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23475 3557e5d8a5321223844b2d026f7e4caa 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 3.7E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23475 3557e5d8a5321223844b2d026f7e4caa 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 3.7E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23475 3557e5d8a5321223844b2d026f7e4caa 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 3.7E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23475 3557e5d8a5321223844b2d026f7e4caa 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 3.7E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23475 3557e5d8a5321223844b2d026f7e4caa 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 3.7E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23475 3557e5d8a5321223844b2d026f7e4caa 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 249 1.0E-47 T 28-03-2018 CU254_RS23475 3557e5d8a5321223844b2d026f7e4caa 251 SUPERFAMILY SSF51735 10 249 1.36E-57 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS23475 3557e5d8a5321223844b2d026f7e4caa 251 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 159 0.0064 T 28-03-2018 CU254_RS23475 3557e5d8a5321223844b2d026f7e4caa 251 Gene3D G3DSA:3.40.50.720 2 251 2.0E-52 T 28-03-2018 CU254_RS03500 1860d98eda36890b1d0c77120d5dc5ea 254 Pfam PF02517 CAAX protease self-immunity 109 207 1.3E-10 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CU254_RS24785 e69583e620d24db22909e5e4d4d7537e 217 Gene3D G3DSA:3.40.50.360 1 202 1.0E-44 T 28-03-2018 IPR029039 Flavoprotein-like domain CU254_RS24785 e69583e620d24db22909e5e4d4d7537e 217 ProSitePatterns PS00201 Flavodoxin signature. 7 23 - T 28-03-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 CU254_RS24785 e69583e620d24db22909e5e4d4d7537e 217 SUPERFAMILY SSF52218 3 193 9.44E-51 T 28-03-2018 IPR029039 Flavoprotein-like domain CU254_RS24785 e69583e620d24db22909e5e4d4d7537e 217 Pfam PF03358 NADPH-dependent FMN reductase 4 148 4.4E-14 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CU254_RS24785 e69583e620d24db22909e5e4d4d7537e 217 TIGRFAM TIGR01755 flav_wrbA: NAD(P)H:quinone oxidoreductase, type IV 4 195 3.5E-41 T 28-03-2018 IPR010089 Flavoprotein WrbA-like GO:0003955|GO:0010181 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 CU254_RS21885 ddb0368f2b9852d825156ed71061e916 122 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 4 111 1.1E-25 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CU254_RS21885 ddb0368f2b9852d825156ed71061e916 122 TIGRFAM TIGR00494 crcB: protein CrcB 4 113 1.3E-25 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CU254_RS21885 ddb0368f2b9852d825156ed71061e916 122 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 3 118 18.196 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CU254_RS26920 1f20b47f547bdd6bec2eb887a407125b 210 Pfam PF08241 Methyltransferase domain 25 118 5.6E-15 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CU254_RS26920 1f20b47f547bdd6bec2eb887a407125b 210 Gene3D G3DSA:3.40.50.150 2 147 1.6E-25 T 28-03-2018 CU254_RS26920 1f20b47f547bdd6bec2eb887a407125b 210 SUPERFAMILY SSF53335 6 130 6.33E-28 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS02995 3076b58c8837749d9f1893bd5d961ff1 147 SUPERFAMILY SSF52799 52 144 1.21E-17 T 28-03-2018 IPR029021 Protein-tyrosine phosphatase-like CU254_RS02995 3076b58c8837749d9f1893bd5d961ff1 147 Gene3D G3DSA:3.90.190.10 37 146 8.8E-11 T 28-03-2018 IPR029021 Protein-tyrosine phosphatase-like CU254_RS29460 aa1451d642677e8ecaf7b5ed0d069804 546 SUPERFAMILY SSF46689 494 542 1.82E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS29460 aa1451d642677e8ecaf7b5ed0d069804 546 SUPERFAMILY SSF55781 49 190 7.85E-5 T 28-03-2018 IPR029016 GAF domain-like CU254_RS29460 aa1451d642677e8ecaf7b5ed0d069804 546 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 508 525 1.1E-8 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CU254_RS29460 aa1451d642677e8ecaf7b5ed0d069804 546 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 525 545 1.1E-8 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CU254_RS29460 aa1451d642677e8ecaf7b5ed0d069804 546 Gene3D G3DSA:1.10.10.60 500 544 6.6E-13 T 28-03-2018 CU254_RS29460 aa1451d642677e8ecaf7b5ed0d069804 546 Gene3D G3DSA:1.10.8.60 422 490 2.0E-9 T 28-03-2018 CU254_RS29460 aa1451d642677e8ecaf7b5ed0d069804 546 Pfam PF02954 Bacterial regulatory protein, Fis family 502 541 1.5E-13 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CU254_RS29460 aa1451d642677e8ecaf7b5ed0d069804 546 SUPERFAMILY SSF52540 292 490 2.45E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS25265 db72746c0c7dc201ba845629898130e9 307 SUPERFAMILY SSF53613 4 306 3.12E-71 T 28-03-2018 IPR029056 Ribokinase-like CU254_RS25265 db72746c0c7dc201ba845629898130e9 307 Pfam PF00294 pfkB family carbohydrate kinase 5 300 3.6E-57 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CU254_RS25265 db72746c0c7dc201ba845629898130e9 307 Gene3D G3DSA:3.40.1190.20 1 307 2.6E-69 T 28-03-2018 IPR029056 Ribokinase-like CU254_RS25265 db72746c0c7dc201ba845629898130e9 307 Hamap MF_01987 Ribokinase [rbsK]. 3 307 24.019 T 28-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 CU254_RS25265 db72746c0c7dc201ba845629898130e9 307 PRINTS PR00990 Ribokinase signature 105 118 4.6E-29 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CU254_RS25265 db72746c0c7dc201ba845629898130e9 307 PRINTS PR00990 Ribokinase signature 7 28 4.6E-29 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CU254_RS25265 db72746c0c7dc201ba845629898130e9 307 PRINTS PR00990 Ribokinase signature 217 228 4.6E-29 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CU254_RS25265 db72746c0c7dc201ba845629898130e9 307 PRINTS PR00990 Ribokinase signature 173 188 4.6E-29 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CU254_RS25265 db72746c0c7dc201ba845629898130e9 307 PRINTS PR00990 Ribokinase signature 34 53 4.6E-29 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CU254_RS25265 db72746c0c7dc201ba845629898130e9 307 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 246 259 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CU254_RS01150 54775f5ed8b95f1108767d4233ad3dee 309 Gene3D G3DSA:3.40.190.10 96 188 3.2E-34 T 28-03-2018 CU254_RS01150 54775f5ed8b95f1108767d4233ad3dee 309 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 1 297 7.3E-89 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CU254_RS01150 54775f5ed8b95f1108767d4233ad3dee 309 SUPERFAMILY SSF53850 1 206 2.04E-65 T 28-03-2018 CU254_RS01150 54775f5ed8b95f1108767d4233ad3dee 309 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 1 299 32.953 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CU254_RS01150 54775f5ed8b95f1108767d4233ad3dee 309 PRINTS PR00151 Porphobilinogen deaminase signature 65 84 1.1E-23 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CU254_RS01150 54775f5ed8b95f1108767d4233ad3dee 309 PRINTS PR00151 Porphobilinogen deaminase signature 220 237 1.1E-23 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CU254_RS01150 54775f5ed8b95f1108767d4233ad3dee 309 PRINTS PR00151 Porphobilinogen deaminase signature 132 149 1.1E-23 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CU254_RS01150 54775f5ed8b95f1108767d4233ad3dee 309 PRINTS PR00151 Porphobilinogen deaminase signature 113 130 1.1E-23 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CU254_RS01150 54775f5ed8b95f1108767d4233ad3dee 309 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 221 237 - T 28-03-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CU254_RS01150 54775f5ed8b95f1108767d4233ad3dee 309 PIRSF PIRSF001438 1 308 1.1E-103 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CU254_RS01150 54775f5ed8b95f1108767d4233ad3dee 309 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 1 201 3.6E-67 T 28-03-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CU254_RS01150 54775f5ed8b95f1108767d4233ad3dee 309 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 217 297 7.8E-14 T 28-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CU254_RS01150 54775f5ed8b95f1108767d4233ad3dee 309 SUPERFAMILY SSF54782 210 306 1.09E-15 T 28-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CU254_RS01150 54775f5ed8b95f1108767d4233ad3dee 309 Gene3D G3DSA:3.30.160.40 211 307 4.8E-17 T 28-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CU254_RS01150 54775f5ed8b95f1108767d4233ad3dee 309 Gene3D G3DSA:3.40.190.10 1 95 5.3E-33 T 28-03-2018 CU254_RS20400 9f18513386cedae4d7f53371ea9098a1 284 SUPERFAMILY SSF53474 13 279 8.31E-36 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS20400 9f18513386cedae4d7f53371ea9098a1 284 Gene3D G3DSA:3.40.50.1820 10 267 7.4E-14 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS20400 9f18513386cedae4d7f53371ea9098a1 284 Pfam PF00756 Putative esterase 22 196 1.7E-13 T 28-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 CU254_RS28040 a93788a3b73f5e6c77844e5a318bc10e 257 SMART SM00563 71 190 4.9E-24 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CU254_RS28040 a93788a3b73f5e6c77844e5a318bc10e 257 Gene3D G3DSA:3.40.1130.10 27 254 8.1E-45 T 28-03-2018 CU254_RS28040 a93788a3b73f5e6c77844e5a318bc10e 257 Pfam PF01553 Acyltransferase 57 186 8.1E-22 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CU254_RS28040 a93788a3b73f5e6c77844e5a318bc10e 257 SUPERFAMILY SSF69593 38 250 1.7E-38 T 28-03-2018 CU254_RS13980 ec288f14da5e0197b17f40854f095a46 407 Gene3D G3DSA:1.20.1250.20 221 407 1.8E-7 T 28-03-2018 CU254_RS13980 ec288f14da5e0197b17f40854f095a46 407 SUPERFAMILY SSF103473 13 404 4.05E-35 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS13980 ec288f14da5e0197b17f40854f095a46 407 Gene3D G3DSA:1.20.1250.20 11 215 7.5E-25 T 28-03-2018 CU254_RS13980 ec288f14da5e0197b17f40854f095a46 407 Pfam PF07690 Major Facilitator Superfamily 28 275 1.2E-20 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS15070 3ff6def09df4d891b723d2ca96ac37b3 379 Gene3D G3DSA:1.20.1250.20 1 188 6.2E-26 T 28-03-2018 CU254_RS15070 3ff6def09df4d891b723d2ca96ac37b3 379 SUPERFAMILY SSF103473 14 378 7.32E-50 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS15070 3ff6def09df4d891b723d2ca96ac37b3 379 Gene3D G3DSA:1.20.1250.20 189 379 2.9E-16 T 28-03-2018 CU254_RS15070 3ff6def09df4d891b723d2ca96ac37b3 379 PRINTS PR01036 Tetracycline resistance protein TetB signature 281 305 4.5E-9 T 28-03-2018 CU254_RS15070 3ff6def09df4d891b723d2ca96ac37b3 379 PRINTS PR01036 Tetracycline resistance protein TetB signature 127 151 4.5E-9 T 28-03-2018 CU254_RS15070 3ff6def09df4d891b723d2ca96ac37b3 379 PRINTS PR01036 Tetracycline resistance protein TetB signature 97 117 4.5E-9 T 28-03-2018 CU254_RS15070 3ff6def09df4d891b723d2ca96ac37b3 379 Pfam PF07690 Major Facilitator Superfamily 11 260 2.8E-28 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS23765 939388d4118697933e34be531f066833 227 Gene3D G3DSA:1.10.530.10 8 125 1.8E-16 T 28-03-2018 CU254_RS23765 939388d4118697933e34be531f066833 227 SUPERFAMILY SSF54106 179 225 5.1E-5 T 28-03-2018 IPR018392 LysM domain CU254_RS23765 939388d4118697933e34be531f066833 227 Pfam PF06737 Transglycosylase-like domain 48 120 1.2E-12 T 28-03-2018 IPR010618 Transglycosylase-like CU254_RS23765 939388d4118697933e34be531f066833 227 SUPERFAMILY SSF53955 47 123 5.63E-16 T 28-03-2018 IPR023346 Lysozyme-like domain CU254_RS23765 939388d4118697933e34be531f066833 227 SMART SM00257 179 227 2.6E-7 T 28-03-2018 IPR018392 LysM domain CU254_RS23765 939388d4118697933e34be531f066833 227 Pfam PF01476 LysM domain 180 225 2.5E-7 T 28-03-2018 IPR018392 LysM domain CU254_RS23765 939388d4118697933e34be531f066833 227 Gene3D G3DSA:3.10.350.10 166 226 3.3E-11 T 28-03-2018 CU254_RS33440 1a2ebc42c977968c39ce544ac3cc62b2 63 Pfam PF13459 4Fe-4S single cluster domain 3 60 2.5E-9 T 28-03-2018 CU254_RS33440 1a2ebc42c977968c39ce544ac3cc62b2 63 Gene3D G3DSA:3.30.70.20 1 63 2.9E-6 T 28-03-2018 CU254_RS33440 1a2ebc42c977968c39ce544ac3cc62b2 63 SUPERFAMILY SSF54862 2 61 5.68E-10 T 28-03-2018 CU254_RS24580 6eb5db240234e90790abed8cf326c3fe 472 SUPERFAMILY SSF53244 322 463 2.59E-43 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CU254_RS24580 6eb5db240234e90790abed8cf326c3fe 472 SUPERFAMILY SSF53623 101 321 5.72E-56 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CU254_RS24580 6eb5db240234e90790abed8cf326c3fe 472 Gene3D G3DSA:3.90.190.20 324 467 5.5E-38 T 28-03-2018 CU254_RS24580 6eb5db240234e90790abed8cf326c3fe 472 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 11 467 38.202 T 28-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CU254_RS24580 6eb5db240234e90790abed8cf326c3fe 472 Gene3D G3DSA:3.40.50.720 4 103 1.1E-17 T 28-03-2018 CU254_RS24580 6eb5db240234e90790abed8cf326c3fe 472 Pfam PF08245 Mur ligase middle domain 120 302 4.0E-28 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CU254_RS24580 6eb5db240234e90790abed8cf326c3fe 472 Pfam PF01225 Mur ligase family, catalytic domain 15 116 6.2E-27 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CU254_RS24580 6eb5db240234e90790abed8cf326c3fe 472 SUPERFAMILY SSF51984 12 103 1.31E-23 T 28-03-2018 CU254_RS24580 6eb5db240234e90790abed8cf326c3fe 472 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 14 461 1.1E-145 T 28-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CU254_RS24580 6eb5db240234e90790abed8cf326c3fe 472 Pfam PF02875 Mur ligase family, glutamate ligase domain 323 408 1.5E-23 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CU254_RS24580 6eb5db240234e90790abed8cf326c3fe 472 Gene3D G3DSA:3.40.1190.10 104 323 2.5E-46 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CU254_RS16845 195110ffa6a2cdaf3d8a7beb02767065 500 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 81 400 2.5E-72 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CU254_RS16845 195110ffa6a2cdaf3d8a7beb02767065 500 Gene3D G3DSA:3.40.190.10 162 284 1.6E-33 T 28-03-2018 CU254_RS16845 195110ffa6a2cdaf3d8a7beb02767065 500 SUPERFAMILY SSF53850 29 489 2.26E-96 T 28-03-2018 CU254_RS16845 195110ffa6a2cdaf3d8a7beb02767065 500 Gene3D G3DSA:3.90.76.10 58 161 5.9E-26 T 28-03-2018 CU254_RS16845 195110ffa6a2cdaf3d8a7beb02767065 500 Gene3D G3DSA:3.10.105.10 285 465 2.4E-26 T 28-03-2018 CU254_RS40535 a60e88cd789a845d0e8014d4fd145004 351 Pfam PF09084 NMT1/THI5 like 56 267 8.9E-17 T 28-03-2018 IPR015168 SsuA/THI5-like CU254_RS40535 a60e88cd789a845d0e8014d4fd145004 351 Gene3D G3DSA:3.40.190.10 38 133 1.5E-9 T 28-03-2018 CU254_RS40535 a60e88cd789a845d0e8014d4fd145004 351 Gene3D G3DSA:3.40.190.10 137 346 5.8E-24 T 28-03-2018 CU254_RS40535 a60e88cd789a845d0e8014d4fd145004 351 SUPERFAMILY SSF53850 39 282 9.57E-33 T 28-03-2018 CU254_RS07295 13540afbdc4c7aa8d65c5862efaa238d 325 Gene3D G3DSA:3.20.20.30 6 325 1.5E-80 T 28-03-2018 CU254_RS07295 13540afbdc4c7aa8d65c5862efaa238d 325 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 3 322 2.9E-133 T 28-03-2018 IPR019949 Luciferase family oxidoreductase, group 1 CU254_RS07295 13540afbdc4c7aa8d65c5862efaa238d 325 Pfam PF00296 Luciferase-like monooxygenase 18 296 2.7E-35 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS07295 13540afbdc4c7aa8d65c5862efaa238d 325 SUPERFAMILY SSF51679 2 322 3.79E-81 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS26770 1b7ab612d1f48c9ac2b1f60de3ee9754 702 SUPERFAMILY SSF53271 657 699 6.03E-11 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CU254_RS26770 1b7ab612d1f48c9ac2b1f60de3ee9754 702 SUPERFAMILY SSF52540 70 360 7.62E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS26770 1b7ab612d1f48c9ac2b1f60de3ee9754 702 Gene3D G3DSA:3.40.50.300 4 207 2.3E-27 T 28-03-2018 CU254_RS26770 1b7ab612d1f48c9ac2b1f60de3ee9754 702 Pfam PF00271 Helicase conserved C-terminal domain 245 342 5.7E-13 T 28-03-2018 IPR001650 Helicase, C-terminal CU254_RS26770 1b7ab612d1f48c9ac2b1f60de3ee9754 702 Pfam PF00270 DEAD/DEAH box helicase 28 195 6.1E-16 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CU254_RS26770 1b7ab612d1f48c9ac2b1f60de3ee9754 702 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 24 356 8.0E-68 T 28-03-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 CU254_RS26770 1b7ab612d1f48c9ac2b1f60de3ee9754 702 Gene3D G3DSA:3.40.50.300 226 363 1.6E-26 T 28-03-2018 CU254_RS26770 1b7ab612d1f48c9ac2b1f60de3ee9754 702 Gene3D G3DSA:1.10.10.10 446 581 1.1E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS26770 1b7ab612d1f48c9ac2b1f60de3ee9754 702 SMART SM00487 21 221 4.7E-24 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CU254_RS26770 1b7ab612d1f48c9ac2b1f60de3ee9754 702 Gene3D G3DSA:1.10.10.10 364 445 2.5E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS26770 1b7ab612d1f48c9ac2b1f60de3ee9754 702 SMART SM00490 262 343 1.2E-21 T 28-03-2018 IPR001650 Helicase, C-terminal CU254_RS26770 1b7ab612d1f48c9ac2b1f60de3ee9754 702 Gene3D G3DSA:3.40.50.2020 582 702 7.5E-18 T 28-03-2018 CU254_RS03475 abdad261278bc2ca63dd22e6121a4ca9 234 SUPERFAMILY SSF56801 3 229 1.7E-17 T 28-03-2018 CU254_RS03475 abdad261278bc2ca63dd22e6121a4ca9 234 Gene3D G3DSA:3.40.50.980 174 230 5.4E-6 T 28-03-2018 CU254_RS03475 abdad261278bc2ca63dd22e6121a4ca9 234 Gene3D G3DSA:3.40.50.980 1 173 8.6E-11 T 28-03-2018 CU254_RS03475 abdad261278bc2ca63dd22e6121a4ca9 234 TIGRFAM TIGR03089 TIGR03089: TIGR03089 family protein 12 229 4.9E-60 T 28-03-2018 IPR017523 Conserved hypothetical protein CHP03089 CU254_RS12255 4b4b5e75a299db7d346dd6f3c3cbea8f 372 Pfam PF01494 FAD binding domain 3 338 8.9E-24 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CU254_RS12255 4b4b5e75a299db7d346dd6f3c3cbea8f 372 Gene3D G3DSA:3.50.50.60 3 347 2.3E-46 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS12255 4b4b5e75a299db7d346dd6f3c3cbea8f 372 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 6.5E-19 T 28-03-2018 CU254_RS12255 4b4b5e75a299db7d346dd6f3c3cbea8f 372 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 295 311 6.5E-19 T 28-03-2018 CU254_RS12255 4b4b5e75a299db7d346dd6f3c3cbea8f 372 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 146 161 6.5E-19 T 28-03-2018 CU254_RS12255 4b4b5e75a299db7d346dd6f3c3cbea8f 372 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 280 295 6.5E-19 T 28-03-2018 CU254_RS12255 4b4b5e75a299db7d346dd6f3c3cbea8f 372 SUPERFAMILY SSF51905 3 167 1.07E-58 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS12255 4b4b5e75a299db7d346dd6f3c3cbea8f 372 SUPERFAMILY SSF51905 267 352 1.07E-58 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS12255 4b4b5e75a299db7d346dd6f3c3cbea8f 372 SUPERFAMILY SSF54373 172 264 4.32E-11 T 28-03-2018 CU254_RS36480 c18cb79e490564488cbc0a556128c76c 271 Gene3D G3DSA:2.40.10.10 27 118 7.1E-5 T 28-03-2018 CU254_RS36480 c18cb79e490564488cbc0a556128c76c 271 Pfam PF13365 Trypsin-like peptidase domain 40 209 1.3E-12 T 28-03-2018 CU254_RS36480 c18cb79e490564488cbc0a556128c76c 271 Gene3D G3DSA:2.40.10.10 119 246 1.1E-14 T 28-03-2018 CU254_RS36480 c18cb79e490564488cbc0a556128c76c 271 SUPERFAMILY SSF50494 33 227 4.89E-17 T 28-03-2018 IPR009003 Peptidase S1, PA clan CU254_RS23290 90f90e5f06be8a0d5dcfc8b74e1cf18d 564 Gene3D G3DSA:3.40.50.980 214 368 5.7E-47 T 28-03-2018 CU254_RS23290 90f90e5f06be8a0d5dcfc8b74e1cf18d 564 Pfam PF00501 AMP-binding enzyme 32 458 1.4E-94 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS23290 90f90e5f06be8a0d5dcfc8b74e1cf18d 564 Pfam PF13193 AMP-binding enzyme C-terminal domain 468 543 6.0E-22 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS23290 90f90e5f06be8a0d5dcfc8b74e1cf18d 564 Gene3D G3DSA:2.30.38.10 369 452 3.0E-23 T 28-03-2018 CU254_RS23290 90f90e5f06be8a0d5dcfc8b74e1cf18d 564 SUPERFAMILY SSF56801 23 553 1.7E-151 T 28-03-2018 CU254_RS23290 90f90e5f06be8a0d5dcfc8b74e1cf18d 564 ProSitePatterns PS00455 Putative AMP-binding domain signature. 208 219 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS23290 90f90e5f06be8a0d5dcfc8b74e1cf18d 564 Gene3D G3DSA:3.30.300.30 453 558 1.2E-29 T 28-03-2018 CU254_RS23290 90f90e5f06be8a0d5dcfc8b74e1cf18d 564 Gene3D G3DSA:3.40.50.980 23 213 1.4E-39 T 28-03-2018 CU254_RS24885 f95c2071c85c96118252ab57e1666fe6 89 SUPERFAMILY SSF47060 3 89 1.74E-33 T 28-03-2018 IPR009068 S15/NS1, RNA-binding CU254_RS24885 f95c2071c85c96118252ab57e1666fe6 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 5 89 1.2E-38 T 28-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS24885 f95c2071c85c96118252ab57e1666fe6 89 Gene3D G3DSA:1.10.287.10 2 89 1.3E-34 T 28-03-2018 CU254_RS24885 f95c2071c85c96118252ab57e1666fe6 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 11 88 1.0E-19 T 28-03-2018 CU254_RS24885 f95c2071c85c96118252ab57e1666fe6 89 Pfam PF00312 Ribosomal protein S15 8 88 4.0E-36 T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS24885 f95c2071c85c96118252ab57e1666fe6 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS24885 f95c2071c85c96118252ab57e1666fe6 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 22.217 T 28-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS24885 f95c2071c85c96118252ab57e1666fe6 89 SMART SM01387 8 88 4.1E-48 T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS16870 354c00dcf89119f25b5a1d0468c382cd 154 Gene3D G3DSA:3.30.530.20 1 151 7.5E-20 T 28-03-2018 IPR023393 START-like domain CU254_RS16870 354c00dcf89119f25b5a1d0468c382cd 154 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 2 140 1.6E-8 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase CU254_RS16870 354c00dcf89119f25b5a1d0468c382cd 154 SUPERFAMILY SSF55961 2 141 6.68E-20 T 28-03-2018 CU254_RS31980 48f7b90ca4cdf7f71194a28996aed043 228 Gene3D G3DSA:1.20.120.530 74 219 5.4E-29 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS31980 48f7b90ca4cdf7f71194a28996aed043 228 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 4.8E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS31980 48f7b90ca4cdf7f71194a28996aed043 228 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 4.8E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS31980 48f7b90ca4cdf7f71194a28996aed043 228 SMART SM00895 87 209 8.2E-15 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS31980 48f7b90ca4cdf7f71194a28996aed043 228 Pfam PF07729 FCD domain 87 208 4.3E-19 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS31980 48f7b90ca4cdf7f71194a28996aed043 228 SUPERFAMILY SSF48008 83 215 3.66E-27 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS31980 48f7b90ca4cdf7f71194a28996aed043 228 Gene3D G3DSA:1.10.10.10 4 73 8.6E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS31980 48f7b90ca4cdf7f71194a28996aed043 228 SMART SM00345 19 77 1.6E-18 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS31980 48f7b90ca4cdf7f71194a28996aed043 228 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 77 3.0E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS31980 48f7b90ca4cdf7f71194a28996aed043 228 SUPERFAMILY SSF46785 8 98 1.71E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS03695 198fa4eb161c1426223d4e0560b0e675 387 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 6 251 3.9E-87 T 28-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 CU254_RS03695 198fa4eb161c1426223d4e0560b0e675 387 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 263 372 1.2E-22 T 28-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 CU254_RS03045 8f1ea1e48838a338d554ec87a20dd93d 365 Pfam PF00512 His Kinase A (phospho-acceptor) domain 149 205 1.3E-8 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS03045 8f1ea1e48838a338d554ec87a20dd93d 365 PRINTS PR00344 Bacterial sensor protein C-terminal signature 326 344 3.0E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS03045 8f1ea1e48838a338d554ec87a20dd93d 365 PRINTS PR00344 Bacterial sensor protein C-terminal signature 312 322 3.0E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS03045 8f1ea1e48838a338d554ec87a20dd93d 365 PRINTS PR00344 Bacterial sensor protein C-terminal signature 350 363 3.0E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS03045 8f1ea1e48838a338d554ec87a20dd93d 365 PRINTS PR00344 Bacterial sensor protein C-terminal signature 294 308 3.0E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS03045 8f1ea1e48838a338d554ec87a20dd93d 365 Gene3D G3DSA:3.30.565.10 213 365 3.0E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS03045 8f1ea1e48838a338d554ec87a20dd93d 365 SMART SM00387 256 364 8.9E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS03045 8f1ea1e48838a338d554ec87a20dd93d 365 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 257 363 1.3E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS03045 8f1ea1e48838a338d554ec87a20dd93d 365 SUPERFAMILY SSF47384 137 207 6.87E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS03045 8f1ea1e48838a338d554ec87a20dd93d 365 SUPERFAMILY SSF55874 208 362 1.7E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS03045 8f1ea1e48838a338d554ec87a20dd93d 365 SMART SM00388 148 211 1.1E-7 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS03045 8f1ea1e48838a338d554ec87a20dd93d 365 Gene3D G3DSA:1.10.287.130 139 206 7.3E-10 T 28-03-2018 CU254_RS08050 4ebc274f5223a61d76632b41d206ab2f 271 SUPERFAMILY SSF54713 57 88 6.79E-40 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CU254_RS08050 4ebc274f5223a61d76632b41d206ab2f 271 SUPERFAMILY SSF54713 173 269 6.79E-40 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CU254_RS08050 4ebc274f5223a61d76632b41d206ab2f 271 Pfam PF00889 Elongation factor TS 67 270 4.2E-61 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CU254_RS08050 4ebc274f5223a61d76632b41d206ab2f 271 Gene3D G3DSA:1.10.286.20 202 222 4.8E-16 T 28-03-2018 CU254_RS08050 4ebc274f5223a61d76632b41d206ab2f 271 Gene3D G3DSA:1.10.8.10 1 54 2.9E-21 T 28-03-2018 CU254_RS08050 4ebc274f5223a61d76632b41d206ab2f 271 Hamap MF_00050 Elongation factor Ts [tsf]. 1 271 65.918 T 28-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CU254_RS08050 4ebc274f5223a61d76632b41d206ab2f 271 SUPERFAMILY SSF46934 3 56 4.79E-17 T 28-03-2018 IPR009060 UBA-like GO:0005515 CU254_RS08050 4ebc274f5223a61d76632b41d206ab2f 271 Gene3D G3DSA:3.30.479.20 150 201 3.2E-5 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CU254_RS08050 4ebc274f5223a61d76632b41d206ab2f 271 Gene3D G3DSA:3.30.479.20 223 269 5.4E-13 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CU254_RS08050 4ebc274f5223a61d76632b41d206ab2f 271 ProSitePatterns PS01126 Elongation factor Ts signature 1. 12 27 - T 28-03-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CU254_RS08050 4ebc274f5223a61d76632b41d206ab2f 271 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 270 1.1E-76 T 28-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CU254_RS08050 4ebc274f5223a61d76632b41d206ab2f 271 Gene3D G3DSA:3.30.479.20 55 149 5.9E-16 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CU254_RS27405 91cd09f8d79a0c573d26de408945e802 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 69 7.3E-17 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS27405 91cd09f8d79a0c573d26de408945e802 213 Gene3D G3DSA:1.10.10.60 8 69 7.0E-22 T 28-03-2018 CU254_RS27405 91cd09f8d79a0c573d26de408945e802 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 3.8E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS27405 91cd09f8d79a0c573d26de408945e802 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 3.8E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS27405 91cd09f8d79a0c573d26de408945e802 213 Gene3D G3DSA:1.10.357.10 70 207 3.6E-17 T 28-03-2018 CU254_RS27405 91cd09f8d79a0c573d26de408945e802 213 SUPERFAMILY SSF46689 11 92 4.1E-20 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS27405 91cd09f8d79a0c573d26de408945e802 213 SUPERFAMILY SSF48498 100 205 6.02E-14 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS27405 91cd09f8d79a0c573d26de408945e802 213 ProSitePatterns PS01081 TetR-type HTH domain signature. 35 66 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CU254_RS34630 d993bb1e5e9d827bc9d6d1806d34e622 291 SMART SM00797 26 291 2.9E-88 T 28-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CU254_RS34630 d993bb1e5e9d827bc9d6d1806d34e622 291 SUPERFAMILY SSF50891 178 284 1.33E-13 T 28-03-2018 IPR029000 Cyclophilin-like domain CU254_RS34630 d993bb1e5e9d827bc9d6d1806d34e622 291 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 27 283 7.7E-82 T 28-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CU254_RS34630 d993bb1e5e9d827bc9d6d1806d34e622 291 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 5 284 2.9E-78 T 28-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CU254_RS30715 c3ab6a845eaa8103c6bbf427d89be674 376 Gene3D G3DSA:3.60.21.10 147 361 3.2E-25 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CU254_RS30715 c3ab6a845eaa8103c6bbf427d89be674 376 Pfam PF00149 Calcineurin-like phosphoesterase 150 318 5.9E-10 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CU254_RS30715 c3ab6a845eaa8103c6bbf427d89be674 376 SUPERFAMILY SSF56300 150 374 6.89E-38 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CU254_RS32340 5a49d150a9b7beac218f1c2ef892db48 107 TIGRFAM TIGR03988 antisig_RsrA: mycothiol system anti-sigma-R factor 13 87 3.5E-28 T 28-03-2018 IPR024020 Anti sigma-R factor, mycothiol system,RsrA CU254_RS32340 5a49d150a9b7beac218f1c2ef892db48 107 TIGRFAM TIGR02949 anti_SigH_actin: anti-sigma factor, TIGR02949 family 9 87 2.7E-25 T 28-03-2018 IPR014295 Anti-sigma factor CU254_RS32340 5a49d150a9b7beac218f1c2ef892db48 107 Pfam PF13490 Putative zinc-finger 13 46 1.7E-7 T 28-03-2018 IPR027383 Putative zinc-finger CU254_RS28550 bfa8f524284eb106d8ef0aeeecff49ff 505 SUPERFAMILY SSF53790 260 489 1.14E-50 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CU254_RS28550 bfa8f524284eb106d8ef0aeeecff49ff 505 SUPERFAMILY SSF53790 1 235 1.03E-48 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CU254_RS28550 bfa8f524284eb106d8ef0aeeecff49ff 505 Gene3D G3DSA:3.30.950.10 145 217 0.094 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CU254_RS28550 bfa8f524284eb106d8ef0aeeecff49ff 505 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 101 133 - T 28-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CU254_RS28550 bfa8f524284eb106d8ef0aeeecff49ff 505 Gene3D G3DSA:3.40.1010.10 2 144 9.3E-33 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CU254_RS28550 bfa8f524284eb106d8ef0aeeecff49ff 505 Gene3D G3DSA:3.40.1010.10 260 380 1.4E-27 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CU254_RS28550 bfa8f524284eb106d8ef0aeeecff49ff 505 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 8 22 - T 28-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CU254_RS28550 bfa8f524284eb106d8ef0aeeecff49ff 505 Gene3D G3DSA:3.30.950.10 381 503 2.2E-50 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CU254_RS28550 bfa8f524284eb106d8ef0aeeecff49ff 505 TIGRFAM TIGR01467 cobI_cbiL: precorrin-2 C(20)-methyltransferase 3 234 2.0E-63 T 28-03-2018 IPR006364 Precorrin-2 C(20)-methyltransferase domain GO:0008757|GO:0009236 CU254_RS28550 bfa8f524284eb106d8ef0aeeecff49ff 505 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 262 469 3.0E-39 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CU254_RS28550 bfa8f524284eb106d8ef0aeeecff49ff 505 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 216 1.9E-48 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CU254_RS28550 bfa8f524284eb106d8ef0aeeecff49ff 505 TIGRFAM TIGR01466 cobJ_cbiH: precorrin-3B C17-methyltransferase 262 504 1.5E-82 T 28-03-2018 IPR006363 Precorrin-3B C17-methyltransferase domain GO:0008168|GO:0009236 CU254_RS16365 ee6c92502e3fea909ace374e05fad43f 295 Gene3D G3DSA:2.20.150.10 9 41 1.2E-12 T 28-03-2018 IPR023314 Tagatose-6-phosphate kinase/1-phosphofructokinase N-terminal domain CU254_RS16365 ee6c92502e3fea909ace374e05fad43f 295 Gene3D G3DSA:3.40.1190.20 42 294 1.0E-39 T 28-03-2018 IPR029056 Ribokinase-like CU254_RS16365 ee6c92502e3fea909ace374e05fad43f 295 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 287 5.6E-71 T 28-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 CU254_RS16365 ee6c92502e3fea909ace374e05fad43f 295 SUPERFAMILY SSF53613 1 276 2.81E-58 T 28-03-2018 IPR029056 Ribokinase-like CU254_RS16365 ee6c92502e3fea909ace374e05fad43f 295 PIRSF PIRSF000535 1 294 6.8E-62 T 28-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 CU254_RS16365 ee6c92502e3fea909ace374e05fad43f 295 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 236 249 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CU254_RS16365 ee6c92502e3fea909ace374e05fad43f 295 Pfam PF00294 pfkB family carbohydrate kinase 15 280 8.7E-38 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CU254_RS30275 52b2d2dd769417182be58b72fe4297e6 161 Gene3D G3DSA:1.20.1290.10 11 159 8.2E-36 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CU254_RS30275 52b2d2dd769417182be58b72fe4297e6 161 Pfam PF02627 Carboxymuconolactone decarboxylase family 21 102 2.6E-19 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CU254_RS30275 52b2d2dd769417182be58b72fe4297e6 161 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 37 85 1.3E-16 T 28-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CU254_RS30275 52b2d2dd769417182be58b72fe4297e6 161 SUPERFAMILY SSF69118 11 155 1.03E-41 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CU254_RS35350 a7440617f3b2c8a964ea103ea473934d 548 Pfam PF13625 Helicase conserved C-terminal domain 6 134 3.9E-45 T 28-03-2018 IPR032830 Helicase XPB/Ssl2, N-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 CU254_RS35350 a7440617f3b2c8a964ea103ea473934d 548 Pfam PF16203 ERCC3/RAD25/XPB C-terminal helicase 353 540 2.6E-46 T 28-03-2018 IPR032438 ERCC3/RAD25/XPB helicase, C-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 CU254_RS35350 a7440617f3b2c8a964ea103ea473934d 548 SMART SM00487 178 353 1.7E-22 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CU254_RS35350 a7440617f3b2c8a964ea103ea473934d 548 Pfam PF04851 Type III restriction enzyme, res subunit 181 326 2.2E-13 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CU254_RS35350 a7440617f3b2c8a964ea103ea473934d 548 SUPERFAMILY SSF52540 387 527 7.67E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS35350 a7440617f3b2c8a964ea103ea473934d 548 SUPERFAMILY SSF52540 284 354 7.67E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS35350 a7440617f3b2c8a964ea103ea473934d 548 SMART SM00490 423 500 9.6E-11 T 28-03-2018 IPR001650 Helicase, C-terminal CU254_RS35350 a7440617f3b2c8a964ea103ea473934d 548 Gene3D G3DSA:3.40.50.300 379 533 1.8E-18 T 28-03-2018 CU254_RS35350 a7440617f3b2c8a964ea103ea473934d 548 Gene3D G3DSA:3.40.50.300 174 355 3.9E-27 T 28-03-2018 CU254_RS35350 a7440617f3b2c8a964ea103ea473934d 548 SUPERFAMILY SSF52540 147 345 1.18E-32 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS23820 076144e1699e824cd745db330447621c 159 Pfam PF00583 Acetyltransferase (GNAT) family 35 135 1.0E-10 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS23820 076144e1699e824cd745db330447621c 159 SUPERFAMILY SSF55729 7 139 1.65E-20 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS23820 076144e1699e824cd745db330447621c 159 Gene3D G3DSA:3.40.630.30 4 155 3.1E-22 T 28-03-2018 CU254_RS15130 01df3938a32486d04cbf2eb949585a28 220 SUPERFAMILY SSF48498 77 190 1.17E-19 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS15130 01df3938a32486d04cbf2eb949585a28 220 Gene3D G3DSA:1.10.10.60 4 61 7.9E-16 T 28-03-2018 CU254_RS15130 01df3938a32486d04cbf2eb949585a28 220 Gene3D G3DSA:1.10.357.10 62 198 5.7E-19 T 28-03-2018 CU254_RS15130 01df3938a32486d04cbf2eb949585a28 220 SUPERFAMILY SSF46689 6 82 8.72E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS15130 01df3938a32486d04cbf2eb949585a28 220 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 56 3.0E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS15130 01df3938a32486d04cbf2eb949585a28 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 1.7E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS15130 01df3938a32486d04cbf2eb949585a28 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 54 1.7E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS03125 363d50a39d6f0c196a8e51040618eb57 618 Gene3D G3DSA:3.20.20.240 55 489 4.3E-148 T 28-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CU254_RS03125 363d50a39d6f0c196a8e51040618eb57 618 SUPERFAMILY SSF51703 15 542 2.98E-152 T 28-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CU254_RS03125 363d50a39d6f0c196a8e51040618eb57 618 Gene3D G3DSA:1.10.196.20 14 50 1.3E-14 T 28-03-2018 IPR024067 Methylmalonyl-CoA mutase small subunit, N-terminal KEGG: 00280+5.4.99.2|KEGG: 00630+5.4.99.2|KEGG: 00640+5.4.99.2|KEGG: 00720+5.4.99.2|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|MetaCyc: PWY-7854 CU254_RS03125 363d50a39d6f0c196a8e51040618eb57 618 Pfam PF01642 Methylmalonyl-CoA mutase 57 536 1.4E-131 T 28-03-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CU254_RS03125 363d50a39d6f0c196a8e51040618eb57 618 Gene3D G3DSA:3.40.50.280 494 618 1.3E-21 T 28-03-2018 CU254_RS18065 d368304845b712060ad4141b8d643e1a 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 251 1.4E-65 T 28-03-2018 CU254_RS18065 d368304845b712060ad4141b8d643e1a 255 PIRSF PIRSF000094 2 255 1.8E-82 T 28-03-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CU254_RS18065 d368304845b712060ad4141b8d643e1a 255 Gene3D G3DSA:3.40.50.720 3 254 3.7E-38 T 28-03-2018 CU254_RS18065 d368304845b712060ad4141b8d643e1a 255 SUPERFAMILY SSF51735 6 252 1.31E-49 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS30555 36075867ca2e59735b1d398fe16a7d2e 399 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 47 386 1.2E-88 T 28-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 CU254_RS30555 36075867ca2e59735b1d398fe16a7d2e 399 SUPERFAMILY SSF54909 40 390 6.79E-88 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS30555 36075867ca2e59735b1d398fe16a7d2e 399 Pfam PF04261 Dyp-type peroxidase family 47 386 1.9E-98 T 28-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 CU254_RS31105 322df788921d613da8f3efee6b96d0b8 370 PIRSF PIRSF001434 1 370 1.5E-110 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CU254_RS31105 322df788921d613da8f3efee6b96d0b8 370 Gene3D G3DSA:3.40.640.10 3 252 3.3E-47 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS31105 322df788921d613da8f3efee6b96d0b8 370 SUPERFAMILY SSF53383 42 368 9.99E-82 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS31105 322df788921d613da8f3efee6b96d0b8 370 Gene3D G3DSA:3.90.1150.10 287 370 1.5E-21 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS31105 322df788921d613da8f3efee6b96d0b8 370 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 7 368 3.6E-90 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CU254_RS31105 322df788921d613da8f3efee6b96d0b8 370 Gene3D G3DSA:3.90.1150.10 253 286 6.4E-6 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS21315 04a99c5b093ef0f104a9832c2ccc47b4 613 SUPERFAMILY SSF56112 27 280 1.73E-70 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS21315 04a99c5b093ef0f104a9832c2ccc47b4 613 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 37 60 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 CU254_RS21315 04a99c5b093ef0f104a9832c2ccc47b4 613 Gene3D G3DSA:3.30.200.20 17 96 1.9E-20 T 28-03-2018 CU254_RS21315 04a99c5b093ef0f104a9832c2ccc47b4 613 Pfam PF00069 Protein kinase domain 31 273 2.4E-49 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CU254_RS21315 04a99c5b093ef0f104a9832c2ccc47b4 613 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 147 159 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CU254_RS21315 04a99c5b093ef0f104a9832c2ccc47b4 613 Gene3D G3DSA:1.10.510.10 97 282 4.1E-52 T 28-03-2018 CU254_RS21315 04a99c5b093ef0f104a9832c2ccc47b4 613 SMART SM00220 31 286 3.2E-62 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CU254_RS27050 73575278bbcf2692c5f5a3df4a575aa6 505 SUPERFAMILY SSF55874 320 486 1.31E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS27050 73575278bbcf2692c5f5a3df4a575aa6 505 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 374 483 4.2E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS27050 73575278bbcf2692c5f5a3df4a575aa6 505 SMART SM00388 264 331 6.9E-22 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS27050 73575278bbcf2692c5f5a3df4a575aa6 505 Gene3D G3DSA:1.10.287.130 251 327 2.2E-16 T 28-03-2018 CU254_RS27050 73575278bbcf2692c5f5a3df4a575aa6 505 SMART SM00304 194 256 9.7E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS27050 73575278bbcf2692c5f5a3df4a575aa6 505 SUPERFAMILY SSF47384 253 332 2.16E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS27050 73575278bbcf2692c5f5a3df4a575aa6 505 Pfam PF00672 HAMP domain 194 251 3.7E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS27050 73575278bbcf2692c5f5a3df4a575aa6 505 SMART SM00387 374 486 1.6E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS27050 73575278bbcf2692c5f5a3df4a575aa6 505 PRINTS PR00344 Bacterial sensor protein C-terminal signature 430 440 3.2E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS27050 73575278bbcf2692c5f5a3df4a575aa6 505 PRINTS PR00344 Bacterial sensor protein C-terminal signature 412 426 3.2E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS27050 73575278bbcf2692c5f5a3df4a575aa6 505 PRINTS PR00344 Bacterial sensor protein C-terminal signature 447 465 3.2E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS27050 73575278bbcf2692c5f5a3df4a575aa6 505 PRINTS PR00344 Bacterial sensor protein C-terminal signature 470 483 3.2E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS27050 73575278bbcf2692c5f5a3df4a575aa6 505 Pfam PF00512 His Kinase A (phospho-acceptor) domain 266 331 2.5E-19 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS27050 73575278bbcf2692c5f5a3df4a575aa6 505 Gene3D G3DSA:3.30.565.10 337 486 1.1E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS08860 aeb75b253a5939c758830bb8ef8b6ab7 140 PIRSF PIRSF017385 1 140 2.8E-48 T 28-03-2018 IPR021050 Cytochrome c oxidase subunit IV, actinobacteria GO:0004129|GO:0016021|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 CU254_RS08860 aeb75b253a5939c758830bb8ef8b6ab7 140 Pfam PF12270 Cytochrome c oxidase subunit IV 1 138 2.4E-50 T 28-03-2018 IPR021050 Cytochrome c oxidase subunit IV, actinobacteria GO:0004129|GO:0016021|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 CU254_RS23150 c713025ee265ea174e2f50c6996fbe29 604 Pfam PF00664 ABC transporter transmembrane region 27 288 6.6E-33 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CU254_RS23150 c713025ee265ea174e2f50c6996fbe29 604 Gene3D G3DSA:1.20.1560.10 7 330 1.7E-56 T 28-03-2018 CU254_RS23150 c713025ee265ea174e2f50c6996fbe29 604 SUPERFAMILY SSF90123 13 323 1.22E-59 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CU254_RS23150 c713025ee265ea174e2f50c6996fbe29 604 SUPERFAMILY SSF52540 336 576 8.91E-77 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS23150 c713025ee265ea174e2f50c6996fbe29 604 Pfam PF00005 ABC transporter 356 505 1.1E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS23150 c713025ee265ea174e2f50c6996fbe29 604 SMART SM00382 365 550 6.0E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS23150 c713025ee265ea174e2f50c6996fbe29 604 Gene3D G3DSA:3.40.50.300 337 604 1.9E-67 T 28-03-2018 CU254_RS23150 c713025ee265ea174e2f50c6996fbe29 604 ProSitePatterns PS00211 ABC transporters family signature. 477 491 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS03575 31f6c38689b01ff4986650e331ff0349 48 Gene3D G3DSA:1.20.5.100 6 48 9.9E-4 T 28-03-2018 CU254_RS03575 31f6c38689b01ff4986650e331ff0349 48 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 13 46 3.3E-5 T 28-03-2018 CU254_RS19870 2dd5e637214ee2fcb3398bdd15196440 274 Pfam PF01261 Xylose isomerase-like TIM barrel 31 231 2.0E-28 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CU254_RS19870 2dd5e637214ee2fcb3398bdd15196440 274 Gene3D G3DSA:3.20.20.150 10 270 1.3E-53 T 28-03-2018 CU254_RS19870 2dd5e637214ee2fcb3398bdd15196440 274 PIRSF PIRSF006241 9 272 7.2E-72 T 28-03-2018 IPR026040 Hydroxypyruvate isomerase-like KEGG: 00630+5.3.1.22 CU254_RS19870 2dd5e637214ee2fcb3398bdd15196440 274 SUPERFAMILY SSF51658 13 267 1.66E-62 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CU254_RS23015 56c56ecf190fd4cc0760ffeb6e6494f0 382 Gene3D G3DSA:3.40.50.2000 1 209 7.6E-67 T 28-03-2018 CU254_RS23015 56c56ecf190fd4cc0760ffeb6e6494f0 382 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 27 362 1.6E-95 T 28-03-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001 CU254_RS23015 56c56ecf190fd4cc0760ffeb6e6494f0 382 Gene3D G3DSA:3.40.50.2000 210 342 2.6E-32 T 28-03-2018 CU254_RS23015 56c56ecf190fd4cc0760ffeb6e6494f0 382 SUPERFAMILY SSF53756 4 365 1.12E-103 T 28-03-2018 CU254_RS23015 56c56ecf190fd4cc0760ffeb6e6494f0 382 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 7 363 2.4E-107 T 28-03-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 CU254_RS35200 a85c33344d72db4844f374a45187affc 359 Pfam PF03459 TOBE domain 290 352 2.8E-11 T 28-03-2018 IPR005116 Transport-associated OB, type 1 CU254_RS35200 a85c33344d72db4844f374a45187affc 359 Gene3D G3DSA:2.40.50.100 287 356 5.0E-15 T 28-03-2018 CU254_RS35200 a85c33344d72db4844f374a45187affc 359 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS35200 a85c33344d72db4844f374a45187affc 359 Gene3D G3DSA:3.40.50.300 15 239 2.3E-62 T 28-03-2018 CU254_RS35200 a85c33344d72db4844f374a45187affc 359 SMART SM00382 24 210 5.1E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS35200 a85c33344d72db4844f374a45187affc 359 Pfam PF00005 ABC transporter 17 162 2.8E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS35200 a85c33344d72db4844f374a45187affc 359 SUPERFAMILY SSF50331 235 353 5.67E-16 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CU254_RS35200 a85c33344d72db4844f374a45187affc 359 SUPERFAMILY SSF52540 7 234 9.38E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS20585 34a2e5d261efb1188a59094b6e20b9da 262 Pfam PF09130 Domain of unknown function (DUF1932) 173 241 4.8E-13 T 28-03-2018 IPR015814 Phosphogluconate dehydrogenase, NAD-binding, putative, C-terminal CU254_RS20585 34a2e5d261efb1188a59094b6e20b9da 262 Gene3D G3DSA:3.40.50.720 1 152 1.2E-17 T 28-03-2018 CU254_RS20585 34a2e5d261efb1188a59094b6e20b9da 262 SUPERFAMILY SSF48179 146 252 6.46E-18 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CU254_RS20585 34a2e5d261efb1188a59094b6e20b9da 262 Gene3D G3DSA:1.10.1040.10 153 245 2.2E-20 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CU254_RS20585 34a2e5d261efb1188a59094b6e20b9da 262 SUPERFAMILY SSF51735 1 122 1.2E-13 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS11740 23c34daf39edf8b476b5a33a4f09905a 326 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 37 315 1.1E-98 T 28-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 CU254_RS11740 23c34daf39edf8b476b5a33a4f09905a 326 Pfam PF01040 UbiA prenyltransferase family 50 298 5.1E-66 T 28-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 CU254_RS11740 23c34daf39edf8b476b5a33a4f09905a 326 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 34 316 18.77 T 28-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 CU254_RS15760 8275c6a3e673a2d16647221777da72a8 285 Gene3D G3DSA:3.20.20.30 16 231 6.9E-61 T 28-03-2018 CU254_RS15760 8275c6a3e673a2d16647221777da72a8 285 Pfam PF00296 Luciferase-like monooxygenase 13 261 3.8E-49 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS15760 8275c6a3e673a2d16647221777da72a8 285 Gene3D G3DSA:3.20.20.30 232 281 0.004 T 28-03-2018 CU254_RS15760 8275c6a3e673a2d16647221777da72a8 285 SUPERFAMILY SSF51679 7 281 2.06E-58 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS10340 8a7c3bec7c012b7114538f647c791a60 236 Gene3D G3DSA:1.10.10.10 2 93 1.3E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS10340 8a7c3bec7c012b7114538f647c791a60 236 SUPERFAMILY SSF46785 9 204 1.36E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS39610 9d074c8b372b771657a8b466fde8f1f3 314 Gene3D G3DSA:1.10.3720.10 1 301 8.2E-38 T 28-03-2018 CU254_RS39610 9d074c8b372b771657a8b466fde8f1f3 314 SUPERFAMILY SSF161098 88 300 5.89E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS39610 9d074c8b372b771657a8b466fde8f1f3 314 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 312 1.0E-32 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS37230 1e2532d7ccbc97ea9a38f6b4974c6f9f 255 SUPERFAMILY SSF46689 45 106 6.16E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS37230 1e2532d7ccbc97ea9a38f6b4974c6f9f 255 Gene3D G3DSA:1.10.10.60 33 99 5.1E-15 T 28-03-2018 CU254_RS37230 1e2532d7ccbc97ea9a38f6b4974c6f9f 255 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 110 247 2.6E-11 T 28-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 CU254_RS37230 1e2532d7ccbc97ea9a38f6b4974c6f9f 255 SUPERFAMILY SSF48498 116 250 4.67E-19 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS37230 1e2532d7ccbc97ea9a38f6b4974c6f9f 255 Pfam PF00440 Bacterial regulatory proteins, tetR family 53 97 5.2E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS37230 1e2532d7ccbc97ea9a38f6b4974c6f9f 255 Gene3D G3DSA:1.10.357.10 100 252 3.6E-25 T 28-03-2018 CU254_RS37230 1e2532d7ccbc97ea9a38f6b4974c6f9f 255 Gene3D G3DSA:3.30.50.10 1 32 1.4E-4 T 28-03-2018 IPR013088 Zinc finger, NHR/GATA-type GO:0006355|GO:0008270 CU254_RS11075 3e5c6562623bb31735134455407dc726 469 TIGRFAM TIGR00562 proto_IX_ox: protoporphyrinogen oxidase 2 465 1.2E-53 T 28-03-2018 IPR004572 Protoporphyrinogen oxidase GO:0004729|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CU254_RS11075 3e5c6562623bb31735134455407dc726 469 Pfam PF01593 Flavin containing amine oxidoreductase 11 463 2.5E-44 T 28-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 CU254_RS11075 3e5c6562623bb31735134455407dc726 469 Gene3D G3DSA:3.40.50.720 1 110 1.1E-16 T 28-03-2018 CU254_RS11075 3e5c6562623bb31735134455407dc726 469 Gene3D G3DSA:3.90.660.20 193 415 4.3E-37 T 28-03-2018 CU254_RS11075 3e5c6562623bb31735134455407dc726 469 SUPERFAMILY SSF54373 304 415 1.02E-21 T 28-03-2018 CU254_RS11075 3e5c6562623bb31735134455407dc726 469 SUPERFAMILY SSF51905 2 319 7.77E-44 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS11075 3e5c6562623bb31735134455407dc726 469 SUPERFAMILY SSF51905 432 464 7.77E-44 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS11075 3e5c6562623bb31735134455407dc726 469 Gene3D G3DSA:1.10.3110.10 111 192 5.7E-16 T 28-03-2018 CU254_RS34545 cce6225e3204fa11d31df4df8205c745 338 Gene3D G3DSA:1.10.630.10 198 303 1.0E-22 T 28-03-2018 CU254_RS34545 cce6225e3204fa11d31df4df8205c745 338 Pfam PF00067 Cytochrome P450 207 294 1.7E-15 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS34545 cce6225e3204fa11d31df4df8205c745 338 PRINTS PR00465 E-class P450 group IV signature 251 269 3.0E-5 T 28-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS34545 cce6225e3204fa11d31df4df8205c745 338 PRINTS PR00465 E-class P450 group IV signature 235 249 3.0E-5 T 28-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS34545 cce6225e3204fa11d31df4df8205c745 338 PRINTS PR00465 E-class P450 group IV signature 202 218 3.0E-5 T 28-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS34545 cce6225e3204fa11d31df4df8205c745 338 SUPERFAMILY SSF48264 203 300 2.88E-21 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS10885 041f548dc7e9b6eb323dbe0dc5dc23af 218 Pfam PF12502 Protein of unknown function (DUF3710) 43 210 8.8E-61 T 28-03-2018 IPR022183 Protein of unknown function DUF3710 CU254_RS03395 1ebcd9e565885871908c2633f0b8b452 758 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 31 187 7.8E-19 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS03395 1ebcd9e565885871908c2633f0b8b452 758 Pfam PF04542 Sigma-70 region 2 31 99 4.3E-12 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS03395 1ebcd9e565885871908c2633f0b8b452 758 Gene3D G3DSA:2.60.40.10 564 725 0.039 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS03395 1ebcd9e565885871908c2633f0b8b452 758 SUPERFAMILY SSF88946 8 102 6.67E-16 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS03395 1ebcd9e565885871908c2633f0b8b452 758 Gene3D G3DSA:1.10.10.10 98 190 1.6E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS03395 1ebcd9e565885871908c2633f0b8b452 758 Gene3D G3DSA:1.10.1740.10 8 97 7.0E-17 T 28-03-2018 CU254_RS03395 1ebcd9e565885871908c2633f0b8b452 758 PRINTS PR01217 Proline rich extensin signature 331 343 3.6E-10 T 28-03-2018 CU254_RS03395 1ebcd9e565885871908c2633f0b8b452 758 PRINTS PR01217 Proline rich extensin signature 390 407 3.6E-10 T 28-03-2018 CU254_RS03395 1ebcd9e565885871908c2633f0b8b452 758 PRINTS PR01217 Proline rich extensin signature 348 369 3.6E-10 T 28-03-2018 CU254_RS03395 1ebcd9e565885871908c2633f0b8b452 758 PRINTS PR01217 Proline rich extensin signature 370 386 3.6E-10 T 28-03-2018 CU254_RS03395 1ebcd9e565885871908c2633f0b8b452 758 Gene3D G3DSA:2.60.40.10 406 542 1.4E-11 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS03395 1ebcd9e565885871908c2633f0b8b452 758 Pfam PF13490 Putative zinc-finger 201 235 1.4E-7 T 28-03-2018 IPR027383 Putative zinc-finger CU254_RS03395 1ebcd9e565885871908c2633f0b8b452 758 SUPERFAMILY SSF88659 125 187 1.87E-8 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS25040 ea633ecad301371ed5838dd21910cc64 444 Gene3D G3DSA:1.20.1250.20 241 441 6.8E-25 T 28-03-2018 CU254_RS25040 ea633ecad301371ed5838dd21910cc64 444 Gene3D G3DSA:1.20.1250.20 15 224 3.0E-36 T 28-03-2018 CU254_RS25040 ea633ecad301371ed5838dd21910cc64 444 Pfam PF07690 Major Facilitator Superfamily 31 396 1.0E-44 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS25040 ea633ecad301371ed5838dd21910cc64 444 SUPERFAMILY SSF103473 12 435 9.42E-79 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS24040 869a6716cb94d8d75a814280c9d1529d 359 SUPERFAMILY SSF53850 97 347 1.89E-23 T 28-03-2018 CU254_RS24040 869a6716cb94d8d75a814280c9d1529d 359 Pfam PF12849 PBP superfamily domain 103 275 1.9E-16 T 28-03-2018 IPR024370 PBP domain CU254_RS24040 869a6716cb94d8d75a814280c9d1529d 359 Gene3D G3DSA:3.40.190.10 151 325 1.9E-19 T 28-03-2018 CU254_RS02950 c171f33066cb106ed934c3c75e2c1fbc 408 Gene3D G3DSA:1.10.630.10 3 408 4.2E-69 T 28-03-2018 CU254_RS02950 c171f33066cb106ed934c3c75e2c1fbc 408 Pfam PF00067 Cytochrome P450 196 377 2.9E-29 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS02950 c171f33066cb106ed934c3c75e2c1fbc 408 SUPERFAMILY SSF48264 18 408 1.26E-88 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS02950 c171f33066cb106ed934c3c75e2c1fbc 408 PRINTS PR00359 B-class P450 signature 327 342 1.3E-52 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS02950 c171f33066cb106ed934c3c75e2c1fbc 408 PRINTS PR00359 B-class P450 signature 99 110 1.3E-52 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS02950 c171f33066cb106ed934c3c75e2c1fbc 408 PRINTS PR00359 B-class P450 signature 299 326 1.3E-52 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS02950 c171f33066cb106ed934c3c75e2c1fbc 408 PRINTS PR00359 B-class P450 signature 348 357 1.3E-52 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS02950 c171f33066cb106ed934c3c75e2c1fbc 408 PRINTS PR00359 B-class P450 signature 146 162 1.3E-52 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS02950 c171f33066cb106ed934c3c75e2c1fbc 408 PRINTS PR00359 B-class P450 signature 163 178 1.3E-52 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS02950 c171f33066cb106ed934c3c75e2c1fbc 408 PRINTS PR00359 B-class P450 signature 357 368 1.3E-52 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS02950 c171f33066cb106ed934c3c75e2c1fbc 408 PRINTS PR00359 B-class P450 signature 200 222 1.3E-52 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS02950 c171f33066cb106ed934c3c75e2c1fbc 408 PRINTS PR00359 B-class P450 signature 281 292 1.3E-52 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS02950 c171f33066cb106ed934c3c75e2c1fbc 408 PRINTS PR00385 P450 superfamily signature 246 263 2.7E-8 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS02950 c171f33066cb106ed934c3c75e2c1fbc 408 PRINTS PR00385 P450 superfamily signature 281 292 2.7E-8 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS02950 c171f33066cb106ed934c3c75e2c1fbc 408 PRINTS PR00385 P450 superfamily signature 357 368 2.7E-8 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS02950 c171f33066cb106ed934c3c75e2c1fbc 408 PRINTS PR00385 P450 superfamily signature 348 357 2.7E-8 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS02950 c171f33066cb106ed934c3c75e2c1fbc 408 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 350 359 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CU254_RS41340 0fda3f08bcd6cfff27a9f31a7cad0b61 477 SUPERFAMILY SSF158745 59 411 5.36E-44 T 28-03-2018 CU254_RS41340 0fda3f08bcd6cfff27a9f31a7cad0b61 477 SMART SM01260 46 424 4.4E-11 T 28-03-2018 IPR007822 Lanthionine synthetase C-like CU254_RS41340 0fda3f08bcd6cfff27a9f31a7cad0b61 477 PRINTS PR01955 Frankia sp. LanC-like protein signature 96 112 2.4E-34 T 28-03-2018 CU254_RS41340 0fda3f08bcd6cfff27a9f31a7cad0b61 477 PRINTS PR01955 Frankia sp. LanC-like protein signature 224 248 2.4E-34 T 28-03-2018 CU254_RS41340 0fda3f08bcd6cfff27a9f31a7cad0b61 477 PRINTS PR01955 Frankia sp. LanC-like protein signature 181 197 2.4E-34 T 28-03-2018 CU254_RS41340 0fda3f08bcd6cfff27a9f31a7cad0b61 477 PRINTS PR01955 Frankia sp. LanC-like protein signature 349 369 2.4E-34 T 28-03-2018 CU254_RS41340 0fda3f08bcd6cfff27a9f31a7cad0b61 477 PRINTS PR01955 Frankia sp. LanC-like protein signature 159 175 2.4E-34 T 28-03-2018 CU254_RS41340 0fda3f08bcd6cfff27a9f31a7cad0b61 477 PRINTS PR01955 Frankia sp. LanC-like protein signature 399 416 2.4E-34 T 28-03-2018 CU254_RS41340 0fda3f08bcd6cfff27a9f31a7cad0b61 477 PRINTS PR01955 Frankia sp. LanC-like protein signature 248 268 2.4E-34 T 28-03-2018 CU254_RS41340 0fda3f08bcd6cfff27a9f31a7cad0b61 477 PRINTS PR01955 Frankia sp. LanC-like protein signature 302 325 2.4E-34 T 28-03-2018 CU254_RS41340 0fda3f08bcd6cfff27a9f31a7cad0b61 477 Pfam PF05147 Lanthionine synthetase C-like protein 87 374 2.4E-19 T 28-03-2018 IPR007822 Lanthionine synthetase C-like CU254_RS29735 053a6ad4b4c9e3ced1ed5685f68d1340 167 SUPERFAMILY SSF55961 3 161 6.72E-38 T 28-03-2018 CU254_RS29735 053a6ad4b4c9e3ced1ed5685f68d1340 167 Gene3D G3DSA:3.30.530.20 2 167 5.6E-27 T 28-03-2018 IPR023393 START-like domain CU254_RS29735 053a6ad4b4c9e3ced1ed5685f68d1340 167 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 25 141 1.0E-16 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CU254_RS14615 e7d2f97360e711a2880c4803a2b87468 114 Pfam PF11338 Protein of unknown function (DUF3140) 14 102 2.2E-25 T 28-03-2018 IPR021487 Protein of unknown function DUF3140 CU254_RS33380 cb10f837eb5153cc4d179ac4c1e7bfb7 295 Gene3D G3DSA:3.40.710.10 1 294 4.1E-33 T 28-03-2018 CU254_RS33380 cb10f837eb5153cc4d179ac4c1e7bfb7 295 SUPERFAMILY SSF56601 179 287 2.82E-40 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CU254_RS33380 cb10f837eb5153cc4d179ac4c1e7bfb7 295 SUPERFAMILY SSF56601 5 149 2.82E-40 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CU254_RS33380 cb10f837eb5153cc4d179ac4c1e7bfb7 295 Pfam PF13354 Beta-lactamase enzyme family 27 263 4.1E-47 T 28-03-2018 CU254_RS28130 e27bd8751261f5f3370e84764f564bf4 234 Gene3D G3DSA:3.40.50.720 37 233 2.0E-55 T 28-03-2018 CU254_RS28130 e27bd8751261f5f3370e84764f564bf4 234 SUPERFAMILY SSF51735 6 231 3.43E-64 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS28130 e27bd8751261f5f3370e84764f564bf4 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 57 68 2.3E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS28130 e27bd8751261f5f3370e84764f564bf4 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 149 2.3E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS28130 e27bd8751261f5f3370e84764f564bf4 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 195 215 2.3E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS28130 e27bd8751261f5f3370e84764f564bf4 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.3E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS28130 e27bd8751261f5f3370e84764f564bf4 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 104 120 2.3E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS28130 e27bd8751261f5f3370e84764f564bf4 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 168 2.3E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS28130 e27bd8751261f5f3370e84764f564bf4 234 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 152 1.5E-4 T 28-03-2018 CU254_RS28130 e27bd8751261f5f3370e84764f564bf4 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 57 68 1.7E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS28130 e27bd8751261f5f3370e84764f564bf4 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 110 118 1.7E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS28130 e27bd8751261f5f3370e84764f564bf4 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 149 1.7E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS28130 e27bd8751261f5f3370e84764f564bf4 234 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 117 145 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS28130 e27bd8751261f5f3370e84764f564bf4 234 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 40 230 4.7E-42 T 28-03-2018 CU254_RS28130 e27bd8751261f5f3370e84764f564bf4 234 Gene3D G3DSA:3.40.50.720 2 36 2.3E-8 T 28-03-2018 CU254_RS20355 2ca1d31eae3895d980bde779ef2ca938 435 Gene3D G3DSA:1.20.1250.20 1 210 2.8E-15 T 28-03-2018 CU254_RS20355 2ca1d31eae3895d980bde779ef2ca938 435 Gene3D G3DSA:1.20.1250.20 216 435 4.5E-21 T 28-03-2018 CU254_RS20355 2ca1d31eae3895d980bde779ef2ca938 435 Pfam PF13347 MFS/sugar transport protein 12 428 9.6E-76 T 28-03-2018 CU254_RS20355 2ca1d31eae3895d980bde779ef2ca938 435 SUPERFAMILY SSF103473 6 423 4.58E-36 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS18060 c987862efa90338844527bd99b9617ec 234 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 127 155 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS18060 c987862efa90338844527bd99b9617ec 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 214 3.4E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18060 c987862efa90338844527bd99b9617ec 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 159 3.4E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18060 c987862efa90338844527bd99b9617ec 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 114 130 3.4E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18060 c987862efa90338844527bd99b9617ec 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 67 78 3.4E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18060 c987862efa90338844527bd99b9617ec 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 178 3.4E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18060 c987862efa90338844527bd99b9617ec 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 3.4E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18060 c987862efa90338844527bd99b9617ec 234 Gene3D G3DSA:3.40.50.720 1 39 2.4E-8 T 28-03-2018 CU254_RS18060 c987862efa90338844527bd99b9617ec 234 Gene3D G3DSA:3.40.50.720 40 234 2.7E-62 T 28-03-2018 CU254_RS18060 c987862efa90338844527bd99b9617ec 234 SUPERFAMILY SSF51735 2 230 1.23E-77 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS18060 c987862efa90338844527bd99b9617ec 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 159 9.3E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18060 c987862efa90338844527bd99b9617ec 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 120 128 9.3E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18060 c987862efa90338844527bd99b9617ec 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 67 78 9.3E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18060 c987862efa90338844527bd99b9617ec 234 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 230 7.8E-57 T 28-03-2018 CU254_RS18060 c987862efa90338844527bd99b9617ec 234 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 176 1.8E-7 T 28-03-2018 CU254_RS30310 a424c89627a527e61f55570cb32f63ad 476 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 6 176 1.4E-32 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CU254_RS30310 a424c89627a527e61f55570cb32f63ad 476 Gene3D G3DSA:3.30.420.40 235 476 1.4E-53 T 28-03-2018 CU254_RS30310 a424c89627a527e61f55570cb32f63ad 476 SUPERFAMILY SSF53067 241 469 6.73E-56 T 28-03-2018 CU254_RS30310 a424c89627a527e61f55570cb32f63ad 476 PIRSF PIRSF000538 3 476 3.5E-108 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CU254_RS30310 a424c89627a527e61f55570cb32f63ad 476 SUPERFAMILY SSF53067 6 238 9.5E-46 T 28-03-2018 CU254_RS30310 a424c89627a527e61f55570cb32f63ad 476 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 246 425 1.3E-37 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CU254_RS30310 a424c89627a527e61f55570cb32f63ad 476 Gene3D G3DSA:3.30.420.40 1 234 3.2E-51 T 28-03-2018 CU254_RS36505 5d1cd93bbe9945ce14ee1809e428c9ac 1025 Pfam PF09369 Domain of unknown function (DUF1998) 906 985 1.7E-17 T 28-03-2018 IPR018973 DEAD/DEAH-box helicase, putative CU254_RS36505 5d1cd93bbe9945ce14ee1809e428c9ac 1025 SUPERFAMILY SSF52540 64 221 1.18E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS36505 5d1cd93bbe9945ce14ee1809e428c9ac 1025 SUPERFAMILY SSF52540 253 399 1.18E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS36505 5d1cd93bbe9945ce14ee1809e428c9ac 1025 Pfam PF00270 DEAD/DEAH box helicase 54 219 1.5E-19 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CU254_RS36505 5d1cd93bbe9945ce14ee1809e428c9ac 1025 TIGRFAM TIGR03817 DECH_helic: helicase/secretion neighborhood putative DEAH-box helicase 15 635 3.4E-300 T 28-03-2018 IPR022307 DEAD/DEAH-box helicase, putative, actinobacteria CU254_RS36505 5d1cd93bbe9945ce14ee1809e428c9ac 1025 Gene3D G3DSA:3.40.50.300 19 243 3.3E-29 T 28-03-2018 CU254_RS36505 5d1cd93bbe9945ce14ee1809e428c9ac 1025 Pfam PF00271 Helicase conserved C-terminal domain 279 389 8.0E-9 T 28-03-2018 IPR001650 Helicase, C-terminal CU254_RS36505 5d1cd93bbe9945ce14ee1809e428c9ac 1025 SMART SM00487 47 249 3.5E-22 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CU254_RS36505 5d1cd93bbe9945ce14ee1809e428c9ac 1025 SMART SM00490 308 389 6.1E-13 T 28-03-2018 IPR001650 Helicase, C-terminal CU254_RS36505 5d1cd93bbe9945ce14ee1809e428c9ac 1025 Gene3D G3DSA:3.40.50.300 273 416 1.2E-18 T 28-03-2018 CU254_RS37125 496ed37c70ff2ec1b09e03723cb398de 139 SMART SM00960 11 101 6.1E-20 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain CU254_RS37125 496ed37c70ff2ec1b09e03723cb398de 139 Gene3D G3DSA:3.30.450.30 1 130 3.1E-31 T 28-03-2018 CU254_RS37125 496ed37c70ff2ec1b09e03723cb398de 139 Pfam PF03259 Roadblock/LC7 domain 11 100 4.4E-15 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain CU254_RS37125 496ed37c70ff2ec1b09e03723cb398de 139 SUPERFAMILY SSF103196 5 126 3.66E-26 T 28-03-2018 CU254_RS01550 8cd05494f1111e5f7b8c40c07f353145 494 Pfam PF04932 O-Antigen ligase 281 409 7.7E-7 T 28-03-2018 IPR007016 O-antigen ligase-related CU254_RS35550 257a595a4139bcca06efa6869282ae7b 495 SUPERFAMILY SSF103473 250 458 2.35E-70 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS35550 257a595a4139bcca06efa6869282ae7b 495 SUPERFAMILY SSF103473 5 198 2.35E-70 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS35550 257a595a4139bcca06efa6869282ae7b 495 Gene3D G3DSA:1.20.1250.20 254 460 5.2E-25 T 28-03-2018 CU254_RS35550 257a595a4139bcca06efa6869282ae7b 495 Gene3D G3DSA:1.20.1250.20 11 202 2.8E-34 T 28-03-2018 CU254_RS35550 257a595a4139bcca06efa6869282ae7b 495 Pfam PF07690 Major Facilitator Superfamily 20 412 7.3E-55 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS35550 257a595a4139bcca06efa6869282ae7b 495 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 18 414 4.8E-73 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CU254_RS07795 868dab1865017e325706aed467214dc5 626 PIRSF PIRSF002583 1 626 1.7E-211 T 28-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 CU254_RS07795 868dab1865017e325706aed467214dc5 626 Pfam PF00183 Hsp90 protein 226 620 1.4E-129 T 28-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 CU254_RS07795 868dab1865017e325706aed467214dc5 626 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 32 185 1.8E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS07795 868dab1865017e325706aed467214dc5 626 SUPERFAMILY SSF55874 8 220 3.95E-62 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS07795 868dab1865017e325706aed467214dc5 626 PRINTS PR00775 90kDa heat shock protein signature 9 29 1.8E-57 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CU254_RS07795 868dab1865017e325706aed467214dc5 626 PRINTS PR00775 90kDa heat shock protein signature 198 216 1.8E-57 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CU254_RS07795 868dab1865017e325706aed467214dc5 626 PRINTS PR00775 90kDa heat shock protein signature 30 52 1.8E-57 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CU254_RS07795 868dab1865017e325706aed467214dc5 626 PRINTS PR00775 90kDa heat shock protein signature 97 114 1.8E-57 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CU254_RS07795 868dab1865017e325706aed467214dc5 626 PRINTS PR00775 90kDa heat shock protein signature 79 96 1.8E-57 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CU254_RS07795 868dab1865017e325706aed467214dc5 626 PRINTS PR00775 90kDa heat shock protein signature 125 147 1.8E-57 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CU254_RS07795 868dab1865017e325706aed467214dc5 626 PRINTS PR00775 90kDa heat shock protein signature 175 192 1.8E-57 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CU254_RS07795 868dab1865017e325706aed467214dc5 626 ProSitePatterns PS00298 Heat shock hsp90 proteins family signature. 29 38 - T 28-03-2018 IPR019805 Heat shock protein Hsp90, conserved site GO:0005524|GO:0006457|GO:0006950|GO:0051082 CU254_RS07795 868dab1865017e325706aed467214dc5 626 SUPERFAMILY SSF110942 506 619 4.45E-30 T 28-03-2018 CU254_RS07795 868dab1865017e325706aed467214dc5 626 Gene3D G3DSA:3.30.565.10 1 233 5.0E-52 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS07795 868dab1865017e325706aed467214dc5 626 SMART SM00387 31 187 1.3E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS07795 868dab1865017e325706aed467214dc5 626 SUPERFAMILY SSF54211 234 487 1.67E-95 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CU254_RS07795 868dab1865017e325706aed467214dc5 626 Hamap MF_00505 Chaperone protein HtpG [htpG]. 1 623 30.065 T 28-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 CU254_RS24420 ad4af6b016a4b7998c22c747485eb4a7 308 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 135 149 - T 28-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 CU254_RS24420 ad4af6b016a4b7998c22c747485eb4a7 308 Gene3D G3DSA:3.30.2350.10 80 308 4.3E-63 T 28-03-2018 CU254_RS24420 ad4af6b016a4b7998c22c747485eb4a7 308 SUPERFAMILY SSF55120 78 305 3.2E-68 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CU254_RS24420 ad4af6b016a4b7998c22c747485eb4a7 308 Gene3D G3DSA:3.10.290.10 4 71 4.8E-13 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CU254_RS24420 ad4af6b016a4b7998c22c747485eb4a7 308 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 13 305 1.5E-84 T 28-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 CU254_RS24420 ad4af6b016a4b7998c22c747485eb4a7 308 Pfam PF00849 RNA pseudouridylate synthase 89 243 3.2E-32 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CU254_RS29515 a14d4e6b40ab144caebb05e0d96e0b0e 109 Gene3D G3DSA:1.10.10.10 2 101 6.0E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS29515 a14d4e6b40ab144caebb05e0d96e0b0e 109 SUPERFAMILY SSF46785 6 95 4.01E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS29515 a14d4e6b40ab144caebb05e0d96e0b0e 109 Pfam PF03551 Transcriptional regulator PadR-like family 8 82 1.3E-19 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CU254_RS29095 d769a90c010c3da4e381366ebebe8162 566 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 88 477 8.9E-60 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CU254_RS29095 d769a90c010c3da4e381366ebebe8162 566 SUPERFAMILY SSF53850 43 559 1.36E-83 T 28-03-2018 CU254_RS29095 d769a90c010c3da4e381366ebebe8162 566 Gene3D G3DSA:3.10.105.10 322 536 2.3E-35 T 28-03-2018 CU254_RS29095 d769a90c010c3da4e381366ebebe8162 566 Gene3D G3DSA:3.40.190.10 183 321 4.3E-29 T 28-03-2018 CU254_RS29095 d769a90c010c3da4e381366ebebe8162 566 PIRSF PIRSF002741 1 556 3.3E-46 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CU254_RS29095 d769a90c010c3da4e381366ebebe8162 566 Gene3D G3DSA:3.90.76.10 64 182 1.4E-18 T 28-03-2018 CU254_RS31760 3a673e90ef1aa056c405fedbf861b297 480 Gene3D G3DSA:3.30.300.30 375 477 2.7E-28 T 28-03-2018 CU254_RS31760 3a673e90ef1aa056c405fedbf861b297 480 ProSitePatterns PS00455 Putative AMP-binding domain signature. 138 149 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS31760 3a673e90ef1aa056c405fedbf861b297 480 Gene3D G3DSA:2.30.38.10 291 374 2.0E-29 T 28-03-2018 CU254_RS31760 3a673e90ef1aa056c405fedbf861b297 480 Pfam PF13193 AMP-binding enzyme C-terminal domain 391 466 8.4E-18 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS31760 3a673e90ef1aa056c405fedbf861b297 480 Pfam PF00501 AMP-binding enzyme 8 382 1.0E-103 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS31760 3a673e90ef1aa056c405fedbf861b297 480 Gene3D G3DSA:3.40.50.980 1 141 3.5E-36 T 28-03-2018 CU254_RS31760 3a673e90ef1aa056c405fedbf861b297 480 Gene3D G3DSA:3.40.50.980 142 290 9.9E-50 T 28-03-2018 CU254_RS31760 3a673e90ef1aa056c405fedbf861b297 480 SUPERFAMILY SSF56801 4 477 1.31E-151 T 28-03-2018 CU254_RS07805 7a2363cb97b523283fe2b6ad4ec5c017 482 Pfam PF01098 Cell cycle protein 67 437 3.8E-79 T 28-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 CU254_RS30765 044cf3b4b6eee765cf1d8f1d097e3832 396 PIRSF PIRSF038800 8 396 3.3E-133 T 28-03-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 CU254_RS30765 044cf3b4b6eee765cf1d8f1d097e3832 396 Gene3D G3DSA:3.90.1150.10 296 396 8.2E-13 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS30765 044cf3b4b6eee765cf1d8f1d097e3832 396 Hamap MF_01970 Kynureninase [kynU]. 3 396 32.546 T 28-03-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 CU254_RS30765 044cf3b4b6eee765cf1d8f1d097e3832 396 Gene3D G3DSA:3.40.640.10 49 295 1.2E-39 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS30765 044cf3b4b6eee765cf1d8f1d097e3832 396 Pfam PF00266 Aminotransferase class-V 81 313 3.9E-17 T 28-03-2018 IPR000192 Aminotransferase class V domain CU254_RS30765 044cf3b4b6eee765cf1d8f1d097e3832 396 SUPERFAMILY SSF53383 13 395 1.06E-80 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS30765 044cf3b4b6eee765cf1d8f1d097e3832 396 TIGRFAM TIGR01814 kynureninase: kynureninase 16 395 5.6E-79 T 28-03-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 CU254_RS04535 f7983f635690724cc3ed3afd00f50e93 320 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 3 209 1.8E-41 T 28-03-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 CU254_RS04535 f7983f635690724cc3ed3afd00f50e93 320 SUPERFAMILY SSF56176 1 209 3.43E-55 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CU254_RS04535 f7983f635690724cc3ed3afd00f50e93 320 Gene3D G3DSA:3.30.465.10 50 120 7.3E-12 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CU254_RS04535 f7983f635690724cc3ed3afd00f50e93 320 Gene3D G3DSA:3.30.465.10 128 209 6.9E-17 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CU254_RS04535 f7983f635690724cc3ed3afd00f50e93 320 SUPERFAMILY SSF55447 216 315 4.32E-28 T 28-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal CU254_RS04535 f7983f635690724cc3ed3afd00f50e93 320 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 217 313 5.0E-18 T 28-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal CU254_RS04535 f7983f635690724cc3ed3afd00f50e93 320 Gene3D G3DSA:3.30.390.50 212 320 5.9E-27 T 28-03-2018 CU254_RS04535 f7983f635690724cc3ed3afd00f50e93 320 SMART SM01092 216 314 3.0E-27 T 28-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal CU254_RS04535 f7983f635690724cc3ed3afd00f50e93 320 Gene3D G3DSA:3.30.43.10 1 46 9.6E-14 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CU254_RS07790 64f9b0c4e1129ff65da8fcedb10a5a04 129 Gene3D G3DSA:3.10.450.50 3 129 1.1E-17 T 28-03-2018 CU254_RS07790 64f9b0c4e1129ff65da8fcedb10a5a04 129 SUPERFAMILY SSF54427 16 128 1.94E-23 T 28-03-2018 IPR032710 NTF2-like domain CU254_RS07790 64f9b0c4e1129ff65da8fcedb10a5a04 129 Pfam PF12680 SnoaL-like domain 18 113 1.5E-12 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CU254_RS07840 a0d2ff0f3b7b4fb5fb01a6fe3a78ed3c 161 TIGRFAM TIGR03180 UraD_2: OHCU decarboxylase 8 159 2.2E-47 T 28-03-2018 IPR017595 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase, type 2 CU254_RS07840 a0d2ff0f3b7b4fb5fb01a6fe3a78ed3c 161 Pfam PF09349 OHCU decarboxylase 9 156 2.2E-35 T 28-03-2018 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 CU254_RS07840 a0d2ff0f3b7b4fb5fb01a6fe3a78ed3c 161 SUPERFAMILY SSF158694 5 158 6.41E-41 T 28-03-2018 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 CU254_RS07840 a0d2ff0f3b7b4fb5fb01a6fe3a78ed3c 161 Gene3D G3DSA:1.10.3330.10 2 161 4.5E-45 T 28-03-2018 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 CU254_RS33800 57abaecbf2b6ce6ea47a7a800a5b97ee 197 SUPERFAMILY SSF53178 12 195 6.28E-64 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CU254_RS33800 57abaecbf2b6ce6ea47a7a800a5b97ee 197 Pfam PF01195 Peptidyl-tRNA hydrolase 13 194 4.3E-53 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CU254_RS33800 57abaecbf2b6ce6ea47a7a800a5b97ee 197 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 117 127 - T 28-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 CU254_RS33800 57abaecbf2b6ce6ea47a7a800a5b97ee 197 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 13 195 2.8E-53 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CU254_RS33800 57abaecbf2b6ce6ea47a7a800a5b97ee 197 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 11 188 32.983 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CU254_RS33800 57abaecbf2b6ce6ea47a7a800a5b97ee 197 Gene3D G3DSA:3.40.50.1470 8 197 4.4E-69 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CU254_RS33800 57abaecbf2b6ce6ea47a7a800a5b97ee 197 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 24 37 - T 28-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 CU254_RS29310 b050b30157d6d1e286898da9d9a0620a 562 Gene3D G3DSA:3.10.580.10 251 380 7.9E-5 T 28-03-2018 CU254_RS29310 b050b30157d6d1e286898da9d9a0620a 562 SUPERFAMILY SSF55073 391 484 3.77E-16 T 28-03-2018 IPR029787 Nucleotide cyclase CU254_RS29310 b050b30157d6d1e286898da9d9a0620a 562 SMART SM00267 375 545 4.4E-6 T 28-03-2018 IPR000160 GGDEF domain CU254_RS29310 b050b30157d6d1e286898da9d9a0620a 562 Pfam PF00563 EAL domain 6 223 1.8E-31 T 28-03-2018 IPR001633 EAL domain CU254_RS29310 b050b30157d6d1e286898da9d9a0620a 562 Pfam PF00990 Diguanylate cyclase, GGDEF domain 399 471 1.1E-12 T 28-03-2018 IPR000160 GGDEF domain CU254_RS29310 b050b30157d6d1e286898da9d9a0620a 562 SUPERFAMILY SSF141868 6 228 6.41E-34 T 28-03-2018 IPR001633 EAL domain CU254_RS29310 b050b30157d6d1e286898da9d9a0620a 562 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 399 472 1.0E-12 T 28-03-2018 IPR000160 GGDEF domain CU254_RS29310 b050b30157d6d1e286898da9d9a0620a 562 Gene3D G3DSA:3.20.20.450 3 238 1.1E-36 T 28-03-2018 IPR001633 EAL domain CU254_RS29310 b050b30157d6d1e286898da9d9a0620a 562 Gene3D G3DSA:3.30.70.270 381 518 4.0E-20 T 28-03-2018 CU254_RS29310 b050b30157d6d1e286898da9d9a0620a 562 SMART SM00052 6 229 9.6E-11 T 28-03-2018 IPR001633 EAL domain CU254_RS21030 f9af4f626bff85e35e250b594040a09b 118 SMART SM00419 30 90 0.004 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CU254_RS21030 f9af4f626bff85e35e250b594040a09b 118 Pfam PF01022 Bacterial regulatory protein, arsR family 35 77 4.1E-10 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS21030 f9af4f626bff85e35e250b594040a09b 118 SUPERFAMILY SSF46785 12 105 1.12E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS21030 f9af4f626bff85e35e250b594040a09b 118 SMART SM00418 25 103 4.6E-20 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS21030 f9af4f626bff85e35e250b594040a09b 118 Gene3D G3DSA:1.10.10.10 9 112 4.5E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS21030 f9af4f626bff85e35e250b594040a09b 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 59 74 4.2E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS21030 f9af4f626bff85e35e250b594040a09b 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 27 42 4.2E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS21030 f9af4f626bff85e35e250b594040a09b 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 74 89 4.2E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS10050 30908d809345b10ca281a46ae944974f 289 SUPERFAMILY SSF55811 6 148 3.25E-28 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CU254_RS10050 30908d809345b10ca281a46ae944974f 289 PRINTS PR00502 NUDIX hydrolase family signature 65 80 2.2E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CU254_RS10050 30908d809345b10ca281a46ae944974f 289 PRINTS PR00502 NUDIX hydrolase family signature 51 65 2.2E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CU254_RS10050 30908d809345b10ca281a46ae944974f 289 Pfam PF00293 NUDIX domain 24 133 8.9E-19 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CU254_RS10050 30908d809345b10ca281a46ae944974f 289 Gene3D G3DSA:3.90.79.10 22 166 3.3E-26 T 28-03-2018 CU254_RS32135 0e964bbd9100b228aeb8b4222169c56e 385 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 340 359 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CU254_RS32135 0e964bbd9100b228aeb8b4222169c56e 385 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 233 381 6.7E-50 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS32135 0e964bbd9100b228aeb8b4222169c56e 385 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 119 5.9E-35 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS32135 0e964bbd9100b228aeb8b4222169c56e 385 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 221 1.4E-20 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CU254_RS32135 0e964bbd9100b228aeb8b4222169c56e 385 Gene3D G3DSA:1.20.140.10 222 382 6.9E-56 T 28-03-2018 CU254_RS32135 0e964bbd9100b228aeb8b4222169c56e 385 PIRSF PIRSF016578 33 383 4.5E-13 T 28-03-2018 CU254_RS32135 0e964bbd9100b228aeb8b4222169c56e 385 SUPERFAMILY SSF56645 2 246 4.97E-81 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS32135 0e964bbd9100b228aeb8b4222169c56e 385 SUPERFAMILY SSF47203 232 381 5.15E-52 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS32135 0e964bbd9100b228aeb8b4222169c56e 385 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 125 137 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CU254_RS32135 0e964bbd9100b228aeb8b4222169c56e 385 Gene3D G3DSA:1.10.540.10 1 121 1.3E-36 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS32135 0e964bbd9100b228aeb8b4222169c56e 385 Gene3D G3DSA:2.40.110.10 122 221 1.5E-34 T 28-03-2018 CU254_RS09715 ea982c3600ddc8c07e31c317fd0cdc3a 305 SUPERFAMILY SSF52540 11 152 5.76E-17 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS09715 ea982c3600ddc8c07e31c317fd0cdc3a 305 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 10 289 3.9E-75 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CU254_RS09715 ea982c3600ddc8c07e31c317fd0cdc3a 305 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 9 301 27.818 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CU254_RS09715 ea982c3600ddc8c07e31c317fd0cdc3a 305 Gene3D G3DSA:1.10.287.890 200 281 2.4E-21 T 28-03-2018 CU254_RS09715 ea982c3600ddc8c07e31c317fd0cdc3a 305 Pfam PF01715 IPP transferase 42 285 6.2E-76 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CU254_RS09715 ea982c3600ddc8c07e31c317fd0cdc3a 305 Gene3D G3DSA:3.40.50.300 5 186 2.9E-61 T 28-03-2018 CU254_RS05095 319ba6ee360f22d2f690ad6881dd47db 525 Gene3D G3DSA:3.40.50.300 12 244 4.9E-57 T 28-03-2018 CU254_RS05095 319ba6ee360f22d2f690ad6881dd47db 525 Pfam PF00005 ABC transporter 32 182 1.8E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS05095 319ba6ee360f22d2f690ad6881dd47db 525 Pfam PF00005 ABC transporter 288 442 1.2E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS05095 319ba6ee360f22d2f690ad6881dd47db 525 SUPERFAMILY SSF52540 15 240 1.74E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS05095 319ba6ee360f22d2f690ad6881dd47db 525 SUPERFAMILY SSF52540 286 502 5.33E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS05095 319ba6ee360f22d2f690ad6881dd47db 525 Gene3D G3DSA:3.40.50.300 273 505 3.2E-42 T 28-03-2018 CU254_RS05095 319ba6ee360f22d2f690ad6881dd47db 525 SMART SM00382 41 229 5.9E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS05095 319ba6ee360f22d2f690ad6881dd47db 525 SMART SM00382 297 491 8.2E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS05095 319ba6ee360f22d2f690ad6881dd47db 525 ProSitePatterns PS00211 ABC transporters family signature. 415 429 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS35865 4bc75db2b72f39e2d6285063e997fa03 423 Gene3D G3DSA:2.102.10.10 37 144 2.0E-27 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CU254_RS35865 4bc75db2b72f39e2d6285063e997fa03 423 Pfam PF00355 Rieske [2Fe-2S] domain 39 122 4.4E-20 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CU254_RS35865 4bc75db2b72f39e2d6285063e997fa03 423 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 186 421 1.3E-17 T 28-03-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 CU254_RS35865 4bc75db2b72f39e2d6285063e997fa03 423 SUPERFAMILY SSF55961 154 422 3.45E-53 T 28-03-2018 CU254_RS35865 4bc75db2b72f39e2d6285063e997fa03 423 SUPERFAMILY SSF50022 8 153 1.57E-48 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CU254_RS35865 4bc75db2b72f39e2d6285063e997fa03 423 Gene3D G3DSA:3.90.380.10 145 423 7.6E-61 T 28-03-2018 CU254_RS35865 4bc75db2b72f39e2d6285063e997fa03 423 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 96 116 3.5E-39 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CU254_RS35865 4bc75db2b72f39e2d6285063e997fa03 423 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 24 49 3.5E-39 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CU254_RS35865 4bc75db2b72f39e2d6285063e997fa03 423 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 138 164 3.5E-39 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CU254_RS35865 4bc75db2b72f39e2d6285063e997fa03 423 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 75 95 3.5E-39 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CU254_RS35865 4bc75db2b72f39e2d6285063e997fa03 423 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 54 69 3.5E-39 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CU254_RS35865 4bc75db2b72f39e2d6285063e997fa03 423 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 179 201 3.5E-39 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CU254_RS26465 52efae87ffb0f86f4415c5c026cf6127 387 SUPERFAMILY SSF49493 218 262 2.09E-15 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CU254_RS26465 52efae87ffb0f86f4415c5c026cf6127 387 SUPERFAMILY SSF49493 120 153 2.09E-15 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CU254_RS26465 52efae87ffb0f86f4415c5c026cf6127 387 SUPERFAMILY SSF49493 263 354 4.84E-19 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CU254_RS26465 52efae87ffb0f86f4415c5c026cf6127 387 Pfam PF01556 DnaJ C terminal domain 124 343 2.2E-36 T 28-03-2018 IPR002939 Chaperone DnaJ, C-terminal CU254_RS26465 52efae87ffb0f86f4415c5c026cf6127 387 PRINTS PR00625 DnaJ domain signature 60 79 1.4E-22 T 28-03-2018 IPR001623 DnaJ domain CU254_RS26465 52efae87ffb0f86f4415c5c026cf6127 387 PRINTS PR00625 DnaJ domain signature 40 60 1.4E-22 T 28-03-2018 IPR001623 DnaJ domain CU254_RS26465 52efae87ffb0f86f4415c5c026cf6127 387 PRINTS PR00625 DnaJ domain signature 6 24 1.4E-22 T 28-03-2018 IPR001623 DnaJ domain CU254_RS26465 52efae87ffb0f86f4415c5c026cf6127 387 PRINTS PR00625 DnaJ domain signature 24 39 1.4E-22 T 28-03-2018 IPR001623 DnaJ domain CU254_RS26465 52efae87ffb0f86f4415c5c026cf6127 387 Gene3D G3DSA:1.10.287.110 1 110 6.1E-29 T 28-03-2018 IPR001623 DnaJ domain CU254_RS26465 52efae87ffb0f86f4415c5c026cf6127 387 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 1 387 36.271 T 28-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 CU254_RS26465 52efae87ffb0f86f4415c5c026cf6127 387 Pfam PF00684 DnaJ central domain 148 212 4.7E-12 T 28-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CU254_RS26465 52efae87ffb0f86f4415c5c026cf6127 387 SUPERFAMILY SSF46565 3 103 3.27E-31 T 28-03-2018 IPR001623 DnaJ domain CU254_RS26465 52efae87ffb0f86f4415c5c026cf6127 387 Gene3D G3DSA:2.60.260.20 260 375 1.2E-27 T 28-03-2018 CU254_RS26465 52efae87ffb0f86f4415c5c026cf6127 387 Gene3D G3DSA:2.60.260.20 172 259 5.3E-16 T 28-03-2018 CU254_RS26465 52efae87ffb0f86f4415c5c026cf6127 387 Gene3D G3DSA:2.60.260.20 115 171 0.071 T 28-03-2018 CU254_RS26465 52efae87ffb0f86f4415c5c026cf6127 387 SUPERFAMILY SSF57938 135 215 1.19E-17 T 28-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CU254_RS26465 52efae87ffb0f86f4415c5c026cf6127 387 SMART SM00271 3 60 2.1E-28 T 28-03-2018 IPR001623 DnaJ domain CU254_RS26465 52efae87ffb0f86f4415c5c026cf6127 387 Pfam PF00226 DnaJ domain 4 65 1.5E-24 T 28-03-2018 IPR001623 DnaJ domain CU254_RS01265 c091674210a1e3ea0daba04521819dc5 289 PIRSF PIRSF005355 1 289 4.3E-86 T 28-03-2018 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 CU254_RS01265 c091674210a1e3ea0daba04521819dc5 289 Hamap MF_01937 1,4-dihydroxy-2-naphthoate octaprenyltransferase [menA]. 3 287 21.306 T 28-03-2018 IPR004657 1,4-dihydroxy-2-naphthoate octaprenyltransferase GO:0009234|GO:0016021|GO:0046428 KEGG: 00130+2.5.1.74|MetaCyc: PWY-5839|MetaCyc: PWY-5851|MetaCyc: PWY-5852|MetaCyc: PWY-5853|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 CU254_RS01265 c091674210a1e3ea0daba04521819dc5 289 Pfam PF01040 UbiA prenyltransferase family 21 250 7.1E-34 T 28-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 CU254_RS01265 c091674210a1e3ea0daba04521819dc5 289 TIGRFAM TIGR00751 menA: 1,4-dihydroxy-2-naphthoate octaprenyltransferase 12 285 7.9E-90 T 28-03-2018 CU254_RS06095 3b60de8afb9cbdd968edf4ddef9a926d 337 Gene3D G3DSA:3.40.50.2300 154 290 1.4E-17 T 28-03-2018 CU254_RS06095 3b60de8afb9cbdd968edf4ddef9a926d 337 Gene3D G3DSA:3.40.50.2300 10 153 2.2E-16 T 28-03-2018 CU254_RS06095 3b60de8afb9cbdd968edf4ddef9a926d 337 SUPERFAMILY SSF53822 38 336 2.36E-53 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CU254_RS06095 3b60de8afb9cbdd968edf4ddef9a926d 337 Pfam PF13407 Periplasmic binding protein domain 39 294 9.8E-44 T 28-03-2018 IPR025997 Periplasmic binding protein CU254_RS11045 2ff4a7956d71eab3700348b48917503c 368 Pfam PF02317 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain 190 333 1.2E-26 T 28-03-2018 IPR003421 Opine dehydrogenase GO:0016491|GO:0050662|GO:0055114 CU254_RS11045 2ff4a7956d71eab3700348b48917503c 368 Gene3D G3DSA:3.40.50.720 1 188 1.8E-22 T 28-03-2018 CU254_RS11045 2ff4a7956d71eab3700348b48917503c 368 Gene3D G3DSA:1.10.1040.10 198 352 7.3E-33 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CU254_RS11045 2ff4a7956d71eab3700348b48917503c 368 SUPERFAMILY SSF48179 192 362 1.6E-44 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CU254_RS11045 2ff4a7956d71eab3700348b48917503c 368 SUPERFAMILY SSF51735 2 182 1.58E-17 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS11045 2ff4a7956d71eab3700348b48917503c 368 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2 106 1.9E-6 T 28-03-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CU254_RS33945 c349deae9a77f786584f57e4393c23e2 507 Gene3D G3DSA:3.40.605.10 8 278 5.0E-91 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CU254_RS33945 c349deae9a77f786584f57e4393c23e2 507 Pfam PF00171 Aldehyde dehydrogenase family 31 494 3.2E-161 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CU254_RS33945 c349deae9a77f786584f57e4393c23e2 507 SUPERFAMILY SSF53720 16 499 1.19E-159 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CU254_RS33945 c349deae9a77f786584f57e4393c23e2 507 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 295 306 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CU254_RS33945 c349deae9a77f786584f57e4393c23e2 507 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 262 269 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CU254_RS33945 c349deae9a77f786584f57e4393c23e2 507 Gene3D G3DSA:3.40.309.10 279 481 1.0E-64 T 28-03-2018 CU254_RS19910 3bf469fca8d3ea5ac19683d03fdb69f8 417 Pfam PF01565 FAD binding domain 32 162 6.8E-30 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CU254_RS19910 3bf469fca8d3ea5ac19683d03fdb69f8 417 Gene3D G3DSA:3.30.465.10 81 203 1.2E-35 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CU254_RS19910 3bf469fca8d3ea5ac19683d03fdb69f8 417 Pfam PF08031 Berberine and berberine like 375 416 1.1E-7 T 28-03-2018 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 CU254_RS19910 3bf469fca8d3ea5ac19683d03fdb69f8 417 Gene3D G3DSA:3.30.43.10 25 80 7.1E-11 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CU254_RS19910 3bf469fca8d3ea5ac19683d03fdb69f8 417 SUPERFAMILY SSF56176 31 196 2.17E-44 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CU254_RS10445 89a7f73ff8a9fa2f7d2ab9d18c623408 558 Pfam PF00890 FAD binding domain 6 531 1.2E-91 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CU254_RS10445 89a7f73ff8a9fa2f7d2ab9d18c623408 558 SUPERFAMILY SSF51905 211 315 7.9E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS10445 89a7f73ff8a9fa2f7d2ab9d18c623408 558 SUPERFAMILY SSF51905 2 117 7.9E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS10445 89a7f73ff8a9fa2f7d2ab9d18c623408 558 SUPERFAMILY SSF51905 490 548 7.9E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS10445 89a7f73ff8a9fa2f7d2ab9d18c623408 558 SUPERFAMILY SSF56425 311 485 2.88E-33 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CU254_RS10445 89a7f73ff8a9fa2f7d2ab9d18c623408 558 Gene3D G3DSA:3.50.50.60 1 548 3.2E-75 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS07585 c96f1fdd05e46e402f4a1cafcb3e8965 292 Pfam PF07728 AAA domain (dynein-related subfamily) 41 193 4.7E-15 T 28-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 CU254_RS07585 c96f1fdd05e46e402f4a1cafcb3e8965 292 Gene3D G3DSA:3.40.50.300 9 237 5.8E-29 T 28-03-2018 CU254_RS07585 c96f1fdd05e46e402f4a1cafcb3e8965 292 SUPERFAMILY SSF52540 37 84 3.04E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS07585 c96f1fdd05e46e402f4a1cafcb3e8965 292 SUPERFAMILY SSF52540 116 269 3.04E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS07585 c96f1fdd05e46e402f4a1cafcb3e8965 292 SMART SM00382 36 219 0.0016 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS05650 41454a847735182de2fcab91aa9910f3 319 Pfam PF13732 Domain of unknown function (DUF4162) 222 307 1.5E-6 T 28-03-2018 IPR025302 Domain of unknown function DUF4162 CU254_RS05650 41454a847735182de2fcab91aa9910f3 319 Pfam PF00005 ABC transporter 25 168 3.0E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS05650 41454a847735182de2fcab91aa9910f3 319 Gene3D G3DSA:3.40.50.300 6 283 2.1E-62 T 28-03-2018 CU254_RS05650 41454a847735182de2fcab91aa9910f3 319 SMART SM00382 34 217 4.1E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS05650 41454a847735182de2fcab91aa9910f3 319 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 17 309 1.7E-101 T 28-03-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 CU254_RS05650 41454a847735182de2fcab91aa9910f3 319 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS05650 41454a847735182de2fcab91aa9910f3 319 SUPERFAMILY SSF52540 8 230 9.35E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS16920 7599bc4e1c0aca63bce84b129c11972d 187 Pfam PF01613 Flavin reductase like domain 13 152 3.9E-30 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CU254_RS16920 7599bc4e1c0aca63bce84b129c11972d 187 Gene3D G3DSA:2.30.110.10 1 162 6.8E-34 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS16920 7599bc4e1c0aca63bce84b129c11972d 187 SMART SM00903 12 151 4.0E-44 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CU254_RS16920 7599bc4e1c0aca63bce84b129c11972d 187 SUPERFAMILY SSF50475 2 155 6.38E-37 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS30465 d00d1787e221c75eb6dd981b222eca12 135 SUPERFAMILY SSF69635 37 128 5.34E-5 T 28-03-2018 CU254_RS30465 d00d1787e221c75eb6dd981b222eca12 135 Gene3D G3DSA:3.30.1460.10 10 132 1.5E-7 T 28-03-2018 CU254_RS12625 cd382c2e1a4a1dbbe88a5c7df4c00e2f 561 SUPERFAMILY SSF53474 394 457 5.01E-5 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS12625 cd382c2e1a4a1dbbe88a5c7df4c00e2f 561 Pfam PF06259 Alpha/beta hydrolase 317 482 6.1E-32 T 28-03-2018 IPR010427 Protein of unknown function DUF1023 CU254_RS12625 cd382c2e1a4a1dbbe88a5c7df4c00e2f 561 Gene3D G3DSA:1.20.120.330 48 300 2.4E-4 T 28-03-2018 CU254_RS12625 cd382c2e1a4a1dbbe88a5c7df4c00e2f 561 Gene3D G3DSA:3.40.50.1820 333 547 4.7E-5 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS18605 87312dd70ecdda242e0ef1798b9a0767 493 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 262 269 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CU254_RS18605 87312dd70ecdda242e0ef1798b9a0767 493 Pfam PF00171 Aldehyde dehydrogenase family 35 488 2.5E-155 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CU254_RS18605 87312dd70ecdda242e0ef1798b9a0767 493 Gene3D G3DSA:3.40.605.10 14 278 3.1E-83 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CU254_RS18605 87312dd70ecdda242e0ef1798b9a0767 493 SUPERFAMILY SSF53720 18 489 1.57E-149 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CU254_RS18605 87312dd70ecdda242e0ef1798b9a0767 493 Gene3D G3DSA:3.40.309.10 279 475 2.0E-73 T 28-03-2018 CU254_RS20360 d56104ef4a9a53a33d73faf0a634b490 341 TIGRFAM TIGR03559 F420_Rv3520c: probable F420-dependent oxidoreductase, Rv3520c family 2 326 8.9E-148 T 28-03-2018 IPR019951 F420-dependent oxidoreductase-predicted, Rv3520c CU254_RS20360 d56104ef4a9a53a33d73faf0a634b490 341 Pfam PF00296 Luciferase-like monooxygenase 16 322 3.0E-77 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS20360 d56104ef4a9a53a33d73faf0a634b490 341 SUPERFAMILY SSF51679 1 328 1.7E-68 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS20360 d56104ef4a9a53a33d73faf0a634b490 341 Gene3D G3DSA:3.20.20.30 1 340 1.1E-69 T 28-03-2018 CU254_RS32685 716e3a21cd9ea7347eafd86e89d4a976 228 Gene3D G3DSA:3.40.50.2300 1 119 1.0E-34 T 28-03-2018 CU254_RS32685 716e3a21cd9ea7347eafd86e89d4a976 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 144 218 1.5E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS32685 716e3a21cd9ea7347eafd86e89d4a976 228 Gene3D G3DSA:1.10.10.10 120 226 5.8E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS32685 716e3a21cd9ea7347eafd86e89d4a976 228 SUPERFAMILY SSF52172 1 166 6.69E-37 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS32685 716e3a21cd9ea7347eafd86e89d4a976 228 SMART SM00448 1 110 3.5E-34 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS32685 716e3a21cd9ea7347eafd86e89d4a976 228 Pfam PF00072 Response regulator receiver domain 1 110 4.6E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS32685 716e3a21cd9ea7347eafd86e89d4a976 228 SMART SM00862 144 219 1.6E-21 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS18690 de518ee29824982a644957647e399265 282 SUPERFAMILY SSF54637 73 141 2.39E-5 T 28-03-2018 IPR029069 HotDog domain CU254_RS18690 de518ee29824982a644957647e399265 282 Gene3D G3DSA:3.10.129.10 5 153 8.1E-16 T 28-03-2018 CU254_RS18690 de518ee29824982a644957647e399265 282 Pfam PF13452 N-terminal half of MaoC dehydratase 44 131 7.0E-9 T 28-03-2018 CU254_RS18690 de518ee29824982a644957647e399265 282 Gene3D G3DSA:3.10.129.10 157 273 2.6E-16 T 28-03-2018 CU254_RS18690 de518ee29824982a644957647e399265 282 SUPERFAMILY SSF54637 172 262 1.77E-12 T 28-03-2018 IPR029069 HotDog domain CU254_RS39230 d96864e46ba3e64de831d386a2627518 47 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 5 47 3.1E-19 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS39230 d96864e46ba3e64de831d386a2627518 47 Pfam PF00468 Ribosomal protein L34 5 47 3.3E-20 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS39230 d96864e46ba3e64de831d386a2627518 47 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 4 47 15.553 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS39230 d96864e46ba3e64de831d386a2627518 47 ProSitePatterns PS00784 Ribosomal protein L34 signature. 5 24 - T 28-03-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS39230 d96864e46ba3e64de831d386a2627518 47 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 5 25 3.0E-5 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS23435 37e03d79c7efe034dd0790aecb2172fa 394 SUPERFAMILY SSF47203 227 365 1.11E-18 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS23435 37e03d79c7efe034dd0790aecb2172fa 394 Gene3D G3DSA:2.40.110.10 110 207 1.1E-14 T 28-03-2018 CU254_RS23435 37e03d79c7efe034dd0790aecb2172fa 394 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 237 367 1.5E-39 T 28-03-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain CU254_RS23435 37e03d79c7efe034dd0790aecb2172fa 394 Gene3D G3DSA:1.10.540.10 4 104 7.1E-6 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS23435 37e03d79c7efe034dd0790aecb2172fa 394 Gene3D G3DSA:1.20.140.10 208 379 1.8E-20 T 28-03-2018 CU254_RS23435 37e03d79c7efe034dd0790aecb2172fa 394 SUPERFAMILY SSF56645 11 206 8.51E-27 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS23435 37e03d79c7efe034dd0790aecb2172fa 394 PIRSF PIRSF016578 1 389 3.6E-127 T 28-03-2018 CU254_RS26400 ba18679faf554fe3d586d4bfb5455f74 272 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 35 263 36.68 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CU254_RS26400 ba18679faf554fe3d586d4bfb5455f74 272 Pfam PF01255 Putative undecaprenyl diphosphate synthase 42 262 8.1E-72 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CU254_RS26400 ba18679faf554fe3d586d4bfb5455f74 272 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 35 262 1.9E-74 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CU254_RS26400 ba18679faf554fe3d586d4bfb5455f74 272 SUPERFAMILY SSF64005 35 258 1.11E-81 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CU254_RS26400 ba18679faf554fe3d586d4bfb5455f74 272 Gene3D G3DSA:3.40.1180.10 25 266 6.3E-81 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CU254_RS26400 ba18679faf554fe3d586d4bfb5455f74 272 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 208 225 - T 28-03-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199 CU254_RS37835 fd1c6cfad8712f9f3120d7ddaccd8753 201 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 109 199 6.2E-7 T 28-03-2018 CU254_RS37835 fd1c6cfad8712f9f3120d7ddaccd8753 201 Gene3D G3DSA:1.10.357.10 4 201 1.0E-26 T 28-03-2018 CU254_RS37835 fd1c6cfad8712f9f3120d7ddaccd8753 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 62 1.8E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS37835 fd1c6cfad8712f9f3120d7ddaccd8753 201 SUPERFAMILY SSF46689 8 75 2.1E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS37835 fd1c6cfad8712f9f3120d7ddaccd8753 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 1.4E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS37835 fd1c6cfad8712f9f3120d7ddaccd8753 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 1.4E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS34300 a0bd2676873c6a6653a360965b4dacc5 618 SUPERFAMILY SSF53335 89 141 2.16E-60 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS34300 a0bd2676873c6a6653a360965b4dacc5 618 SUPERFAMILY SSF53335 359 430 2.16E-60 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS34300 a0bd2676873c6a6653a360965b4dacc5 618 SUPERFAMILY SSF53335 172 309 2.16E-60 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS34300 a0bd2676873c6a6653a360965b4dacc5 618 Pfam PF01555 DNA methylase 121 430 3.0E-36 T 28-03-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 CU254_RS34300 a0bd2676873c6a6653a360965b4dacc5 618 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 411 425 3.2E-12 T 28-03-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 CU254_RS34300 a0bd2676873c6a6653a360965b4dacc5 618 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 184 203 3.2E-12 T 28-03-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 CU254_RS34300 a0bd2676873c6a6653a360965b4dacc5 618 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 121 133 3.2E-12 T 28-03-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 CU254_RS34300 a0bd2676873c6a6653a360965b4dacc5 618 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 388 410 3.2E-12 T 28-03-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 CU254_RS34300 a0bd2676873c6a6653a360965b4dacc5 618 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 124 130 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CU254_RS34300 a0bd2676873c6a6653a360965b4dacc5 618 Gene3D G3DSA:3.40.50.150 98 489 2.3E-51 T 28-03-2018 CU254_RS34300 a0bd2676873c6a6653a360965b4dacc5 618 PIRSF PIRSF015855 2 618 8.4E-169 T 28-03-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 CU254_RS39635 be9fe7010636d715574dc1e7ffdf7997 252 SUPERFAMILY SSF51735 10 242 3.31E-68 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS39635 be9fe7010636d715574dc1e7ffdf7997 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 204 224 2.3E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS39635 be9fe7010636d715574dc1e7ffdf7997 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 2.3E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS39635 be9fe7010636d715574dc1e7ffdf7997 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 2.3E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS39635 be9fe7010636d715574dc1e7ffdf7997 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 2.3E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS39635 be9fe7010636d715574dc1e7ffdf7997 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 2.3E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS39635 be9fe7010636d715574dc1e7ffdf7997 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 2.3E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS39635 be9fe7010636d715574dc1e7ffdf7997 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 241 6.7E-56 T 28-03-2018 CU254_RS39635 be9fe7010636d715574dc1e7ffdf7997 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 135 163 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS39635 be9fe7010636d715574dc1e7ffdf7997 252 Gene3D G3DSA:3.40.50.720 11 250 2.9E-65 T 28-03-2018 CU254_RS15715 1e4e70c16f159e9c7b90bd6c30d6db72 464 ProSitePatterns PS00216 Sugar transport proteins signature 1. 315 332 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CU254_RS15715 1e4e70c16f159e9c7b90bd6c30d6db72 464 Gene3D G3DSA:1.20.1250.20 246 463 5.9E-31 T 28-03-2018 CU254_RS15715 1e4e70c16f159e9c7b90bd6c30d6db72 464 Gene3D G3DSA:1.20.1250.20 12 213 2.4E-35 T 28-03-2018 CU254_RS15715 1e4e70c16f159e9c7b90bd6c30d6db72 464 SUPERFAMILY SSF103473 10 451 1.14E-83 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS15715 1e4e70c16f159e9c7b90bd6c30d6db72 464 ProSitePatterns PS00217 Sugar transport proteins signature 2. 117 142 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CU254_RS15715 1e4e70c16f159e9c7b90bd6c30d6db72 464 Pfam PF00083 Sugar (and other) transporter 53 449 1.8E-46 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CU254_RS31800 fdf116807e426a837a7a3c2bd7c46ce8 359 Gene3D G3DSA:3.20.20.300 34 358 4.6E-58 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CU254_RS31800 fdf116807e426a837a7a3c2bd7c46ce8 359 SUPERFAMILY SSF51445 18 354 1.03E-55 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS31800 fdf116807e426a837a7a3c2bd7c46ce8 359 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 52 352 4.6E-56 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CU254_RS07260 e9eb546f9dde9bb1151431a6e1c1d36b 332 Gene3D G3DSA:1.10.287.1060 233 310 0.02 T 28-03-2018 CU254_RS07260 e9eb546f9dde9bb1151431a6e1c1d36b 332 Pfam PF02470 MlaD protein 33 104 5.4E-13 T 28-03-2018 IPR003399 Mce/MlaD CU254_RS07260 e9eb546f9dde9bb1151431a6e1c1d36b 332 Gene3D G3DSA:1.10.287.950 149 232 0.0016 T 28-03-2018 CU254_RS07260 e9eb546f9dde9bb1151431a6e1c1d36b 332 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 9 296 1.7E-61 T 28-03-2018 IPR005693 Virulence factor Mce protein CU254_RS07920 2b3b05190cf8a60319fe11dc871843b7 769 Gene3D G3DSA:3.30.460.10 42 150 4.6E-8 T 28-03-2018 CU254_RS07920 2b3b05190cf8a60319fe11dc871843b7 769 Gene3D G3DSA:1.10.3090.10 315 563 4.7E-42 T 28-03-2018 CU254_RS07920 2b3b05190cf8a60319fe11dc871843b7 769 SMART SM00471 409 538 4.9E-7 T 28-03-2018 IPR003607 HD/PDEase domain CU254_RS07920 2b3b05190cf8a60319fe11dc871843b7 769 Gene3D G3DSA:3.30.70.260 695 769 1.7E-5 T 28-03-2018 CU254_RS07920 2b3b05190cf8a60319fe11dc871843b7 769 SUPERFAMILY SSF109604 377 484 2.32E-13 T 28-03-2018 CU254_RS07920 2b3b05190cf8a60319fe11dc871843b7 769 Pfam PF01966 HD domain 427 524 7.9E-10 T 28-03-2018 IPR006674 HD domain CU254_RS07920 2b3b05190cf8a60319fe11dc871843b7 769 PIRSF PIRSF006288 566 769 1.6E-21 T 28-03-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 CU254_RS07920 2b3b05190cf8a60319fe11dc871843b7 769 PIRSF PIRSF006288 6 586 4.4E-138 T 28-03-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 CU254_RS07920 2b3b05190cf8a60319fe11dc871843b7 769 SUPERFAMILY SSF81593 174 268 8.63E-5 T 28-03-2018 CU254_RS07920 2b3b05190cf8a60319fe11dc871843b7 769 Gene3D G3DSA:3.30.70.260 581 680 1.1E-5 T 28-03-2018 CU254_RS07920 2b3b05190cf8a60319fe11dc871843b7 769 SUPERFAMILY SSF81301 27 148 3.76E-14 T 28-03-2018 CU254_RS07920 2b3b05190cf8a60319fe11dc871843b7 769 Hamap MF_00277 Bifunctional uridylyltransferase/uridylyl-removing enzyme [glnD]. 1 769 59.404 T 28-03-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 CU254_RS33750 d6f182d47123f6fff2203359570477e1 559 SUPERFAMILY SSF55073 381 530 1.41E-40 T 28-03-2018 IPR029787 Nucleotide cyclase CU254_RS33750 d6f182d47123f6fff2203359570477e1 559 Gene3D G3DSA:1.25.40.10 2 138 3.2E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS33750 d6f182d47123f6fff2203359570477e1 559 Gene3D G3DSA:3.30.70.270 376 538 1.5E-52 T 28-03-2018 CU254_RS33750 d6f182d47123f6fff2203359570477e1 559 Gene3D G3DSA:1.25.40.10 139 375 5.8E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS33750 d6f182d47123f6fff2203359570477e1 559 Pfam PF00990 Diguanylate cyclase, GGDEF domain 376 527 6.6E-41 T 28-03-2018 IPR000160 GGDEF domain CU254_RS33750 d6f182d47123f6fff2203359570477e1 559 SMART SM00267 365 531 3.4E-51 T 28-03-2018 IPR000160 GGDEF domain CU254_RS33750 d6f182d47123f6fff2203359570477e1 559 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 373 529 1.8E-40 T 28-03-2018 IPR000160 GGDEF domain CU254_RS11915 1bc9d3b0a9029656201b67ed6c61f23f 621 SUPERFAMILY SSF90123 27 346 4.71E-74 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CU254_RS11915 1bc9d3b0a9029656201b67ed6c61f23f 621 Gene3D G3DSA:3.40.50.300 345 619 2.2E-70 T 28-03-2018 CU254_RS11915 1bc9d3b0a9029656201b67ed6c61f23f 621 ProSitePatterns PS00211 ABC transporters family signature. 515 529 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS11915 1bc9d3b0a9029656201b67ed6c61f23f 621 Pfam PF00005 ABC transporter 394 543 3.4E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS11915 1bc9d3b0a9029656201b67ed6c61f23f 621 SMART SM00382 403 589 1.0E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS11915 1bc9d3b0a9029656201b67ed6c61f23f 621 SUPERFAMILY SSF52540 379 614 1.63E-82 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS11915 1bc9d3b0a9029656201b67ed6c61f23f 621 Gene3D G3DSA:1.20.1560.10 16 344 2.4E-67 T 28-03-2018 CU254_RS11915 1bc9d3b0a9029656201b67ed6c61f23f 621 Pfam PF00664 ABC transporter transmembrane region 41 312 2.4E-37 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CU254_RS16680 60e36d525c9baa7f5afbeae25e652372 788 Gene3D G3DSA:1.25.40.10 402 611 2.9E-32 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS16680 60e36d525c9baa7f5afbeae25e652372 788 SMART SM00028 496 529 17.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS16680 60e36d525c9baa7f5afbeae25e652372 788 SMART SM00028 560 593 100.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS16680 60e36d525c9baa7f5afbeae25e652372 788 SMART SM00028 432 465 39.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS16680 60e36d525c9baa7f5afbeae25e652372 788 SMART SM00028 624 655 220.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS16680 60e36d525c9baa7f5afbeae25e652372 788 SMART SM00028 656 689 120.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS16680 60e36d525c9baa7f5afbeae25e652372 788 Pfam PF13432 Tetratricopeptide repeat 695 748 0.0036 T 28-03-2018 CU254_RS16680 60e36d525c9baa7f5afbeae25e652372 788 Pfam PF13432 Tetratricopeptide repeat 629 686 0.0012 T 28-03-2018 CU254_RS16680 60e36d525c9baa7f5afbeae25e652372 788 Gene3D G3DSA:1.25.40.10 704 784 8.2E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS16680 60e36d525c9baa7f5afbeae25e652372 788 SUPERFAMILY SSF81901 545 758 1.96E-38 T 28-03-2018 CU254_RS16680 60e36d525c9baa7f5afbeae25e652372 788 Pfam PF08238 Sel1 repeat 512 527 16.0 T 28-03-2018 IPR006597 Sel1-like repeat CU254_RS16680 60e36d525c9baa7f5afbeae25e652372 788 Pfam PF08238 Sel1 repeat 475 495 170.0 T 28-03-2018 IPR006597 Sel1-like repeat CU254_RS16680 60e36d525c9baa7f5afbeae25e652372 788 Pfam PF08238 Sel1 repeat 545 559 1.7 T 28-03-2018 IPR006597 Sel1-like repeat CU254_RS16680 60e36d525c9baa7f5afbeae25e652372 788 Pfam PF08238 Sel1 repeat 434 462 130.0 T 28-03-2018 IPR006597 Sel1-like repeat CU254_RS16680 60e36d525c9baa7f5afbeae25e652372 788 SMART SM00671 560 591 240.0 T 28-03-2018 IPR006597 Sel1-like repeat CU254_RS16680 60e36d525c9baa7f5afbeae25e652372 788 SMART SM00671 496 527 15.0 T 28-03-2018 IPR006597 Sel1-like repeat CU254_RS16680 60e36d525c9baa7f5afbeae25e652372 788 SMART SM00671 592 623 6.2 T 28-03-2018 IPR006597 Sel1-like repeat CU254_RS16680 60e36d525c9baa7f5afbeae25e652372 788 SMART SM00671 720 751 0.72 T 28-03-2018 IPR006597 Sel1-like repeat CU254_RS16680 60e36d525c9baa7f5afbeae25e652372 788 SMART SM00671 624 655 3.4E-4 T 28-03-2018 IPR006597 Sel1-like repeat CU254_RS16680 60e36d525c9baa7f5afbeae25e652372 788 SMART SM00671 528 559 90.0 T 28-03-2018 IPR006597 Sel1-like repeat CU254_RS16680 60e36d525c9baa7f5afbeae25e652372 788 SMART SM00671 464 495 19.0 T 28-03-2018 IPR006597 Sel1-like repeat CU254_RS16680 60e36d525c9baa7f5afbeae25e652372 788 SMART SM00671 432 463 31.0 T 28-03-2018 IPR006597 Sel1-like repeat CU254_RS16680 60e36d525c9baa7f5afbeae25e652372 788 Pfam PF13374 Tetratricopeptide repeat 592 619 0.0013 T 28-03-2018 CU254_RS16680 60e36d525c9baa7f5afbeae25e652372 788 SUPERFAMILY SSF81901 424 601 3.27E-28 T 28-03-2018 CU254_RS16680 60e36d525c9baa7f5afbeae25e652372 788 Pfam PF07721 Tetratricopeptide repeat 568 582 1.0 T 28-03-2018 IPR011717 Tetratricopeptide TPR-4 GO:0042802 CU254_RS16680 60e36d525c9baa7f5afbeae25e652372 788 Gene3D G3DSA:1.25.40.10 665 703 3.5E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS16680 60e36d525c9baa7f5afbeae25e652372 788 Gene3D G3DSA:2.60.40.1180 612 631 1.5E-4 T 28-03-2018 CU254_RS16680 60e36d525c9baa7f5afbeae25e652372 788 Gene3D G3DSA:2.60.40.1180 647 664 0.0022 T 28-03-2018 CU254_RS16680 60e36d525c9baa7f5afbeae25e652372 788 Gene3D G3DSA:1.10.10.10 632 646 0.065 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS23265 e250819bfb2470e593eff077a2bef20c 109 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 8 102 2.4E-14 T 28-03-2018 IPR008407 Branched-chain amino acid transport, AzlD CU254_RS23265 e250819bfb2470e593eff077a2bef20c 109 PIRSF PIRSF003203 1 107 3.2E-28 T 28-03-2018 IPR008407 Branched-chain amino acid transport, AzlD CU254_RS37820 875a13fb1a4ca71552f028a46fbdb7c9 310 SUPERFAMILY SSF46689 259 308 3.03E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS37820 875a13fb1a4ca71552f028a46fbdb7c9 310 Gene3D G3DSA:3.40.50.880 1 222 7.9E-61 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS37820 875a13fb1a4ca71552f028a46fbdb7c9 310 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 259 301 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CU254_RS37820 875a13fb1a4ca71552f028a46fbdb7c9 310 SMART SM00342 222 305 1.8E-26 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS37820 875a13fb1a4ca71552f028a46fbdb7c9 310 Pfam PF01965 DJ-1/PfpI family 4 167 1.7E-20 T 28-03-2018 IPR002818 DJ-1/PfpI CU254_RS37820 875a13fb1a4ca71552f028a46fbdb7c9 310 Gene3D G3DSA:1.10.10.60 265 309 3.2E-12 T 28-03-2018 CU254_RS37820 875a13fb1a4ca71552f028a46fbdb7c9 310 Gene3D G3DSA:1.10.10.60 223 264 5.4E-11 T 28-03-2018 CU254_RS37820 875a13fb1a4ca71552f028a46fbdb7c9 310 Pfam PF12833 Helix-turn-helix domain 228 306 1.0E-22 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS37820 875a13fb1a4ca71552f028a46fbdb7c9 310 SUPERFAMILY SSF52317 4 188 2.67E-45 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS37820 875a13fb1a4ca71552f028a46fbdb7c9 310 SUPERFAMILY SSF46689 208 256 3.19E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS27400 ee096ccd194135db876a0a98fd774d14 882 SUPERFAMILY SSF53474 140 382 2.65E-12 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS27400 ee096ccd194135db876a0a98fd774d14 882 Gene3D G3DSA:3.40.50.1820 99 486 4.5E-12 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS39265 ae3f4eb0a7be5e56e481d22f5dd366a3 875 Gene3D G3DSA:1.10.268.10 353 495 2.2E-48 T 28-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CU254_RS39265 ae3f4eb0a7be5e56e481d22f5dd366a3 875 SUPERFAMILY SSF101904 507 821 2.75E-100 T 28-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal CU254_RS39265 ae3f4eb0a7be5e56e481d22f5dd366a3 875 Gene3D G3DSA:3.90.199.10 38 219 2.7E-81 T 28-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 CU254_RS39265 ae3f4eb0a7be5e56e481d22f5dd366a3 875 Gene3D G3DSA:2.120.10.90 504 817 6.4E-119 T 28-03-2018 CU254_RS39265 ae3f4eb0a7be5e56e481d22f5dd366a3 875 SMART SM00434 15 473 2.1E-264 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CU254_RS39265 ae3f4eb0a7be5e56e481d22f5dd366a3 875 Gene3D G3DSA:3.30.1360.40 244 341 2.1E-33 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CU254_RS39265 ae3f4eb0a7be5e56e481d22f5dd366a3 875 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 3 817 23.592 T 28-03-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CU254_RS39265 ae3f4eb0a7be5e56e481d22f5dd366a3 875 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 666 715 1.4E-9 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CU254_RS39265 ae3f4eb0a7be5e56e481d22f5dd366a3 875 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 619 661 4.5E-9 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CU254_RS39265 ae3f4eb0a7be5e56e481d22f5dd366a3 875 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 769 809 3.5E-10 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CU254_RS39265 ae3f4eb0a7be5e56e481d22f5dd366a3 875 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 562 596 1.1E-9 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CU254_RS39265 ae3f4eb0a7be5e56e481d22f5dd366a3 875 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 719 766 1.2E-10 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CU254_RS39265 ae3f4eb0a7be5e56e481d22f5dd366a3 875 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 512 559 3.8E-12 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CU254_RS39265 ae3f4eb0a7be5e56e481d22f5dd366a3 875 SUPERFAMILY SSF56719 34 496 3.53E-169 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CU254_RS39265 ae3f4eb0a7be5e56e481d22f5dd366a3 875 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 12 815 0.0 T 28-03-2018 CU254_RS39265 ae3f4eb0a7be5e56e481d22f5dd366a3 875 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 36 480 2.6E-147 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CU254_RS39025 d7a02a4c519dc07e99ab73ff280b964c 218 Gene3D G3DSA:1.10.10.10 129 218 3.5E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS39025 d7a02a4c519dc07e99ab73ff280b964c 218 Gene3D G3DSA:3.40.50.2300 5 128 1.7E-32 T 28-03-2018 CU254_RS39025 d7a02a4c519dc07e99ab73ff280b964c 218 SUPERFAMILY SSF52172 6 124 8.54E-32 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS39025 d7a02a4c519dc07e99ab73ff280b964c 218 SMART SM00421 153 210 2.2E-25 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS39025 d7a02a4c519dc07e99ab73ff280b964c 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 210 2.1E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS39025 d7a02a4c519dc07e99ab73ff280b964c 218 SMART SM00448 6 118 1.9E-32 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS39025 d7a02a4c519dc07e99ab73ff280b964c 218 Pfam PF00072 Response regulator receiver domain 8 119 2.8E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS39025 d7a02a4c519dc07e99ab73ff280b964c 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 1.2E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS39025 d7a02a4c519dc07e99ab73ff280b964c 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 1.2E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS39025 d7a02a4c519dc07e99ab73ff280b964c 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 1.2E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS39025 d7a02a4c519dc07e99ab73ff280b964c 218 ProSitePatterns PS00622 LuxR-type HTH domain signature. 170 197 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS39025 d7a02a4c519dc07e99ab73ff280b964c 218 SUPERFAMILY SSF46894 148 215 1.7E-22 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS07470 27111d4e61e0d33f13aef3e880ebd026 252 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 164 0.0038 T 28-03-2018 CU254_RS07470 27111d4e61e0d33f13aef3e880ebd026 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 132 160 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS07470 27111d4e61e0d33f13aef3e880ebd026 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 5.2E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS07470 27111d4e61e0d33f13aef3e880ebd026 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 135 5.2E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS07470 27111d4e61e0d33f13aef3e880ebd026 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 225 5.2E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS07470 27111d4e61e0d33f13aef3e880ebd026 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 5.2E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS07470 27111d4e61e0d33f13aef3e880ebd026 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 164 5.2E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS07470 27111d4e61e0d33f13aef3e880ebd026 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 5.2E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS07470 27111d4e61e0d33f13aef3e880ebd026 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 241 6.1E-61 T 28-03-2018 CU254_RS07470 27111d4e61e0d33f13aef3e880ebd026 252 SUPERFAMILY SSF51735 6 242 1.21E-73 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS07470 27111d4e61e0d33f13aef3e880ebd026 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 72 83 4.1E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS07470 27111d4e61e0d33f13aef3e880ebd026 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 164 4.1E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS07470 27111d4e61e0d33f13aef3e880ebd026 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 125 133 4.1E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS07470 27111d4e61e0d33f13aef3e880ebd026 252 Gene3D G3DSA:3.40.50.720 45 245 1.8E-59 T 28-03-2018 CU254_RS07470 27111d4e61e0d33f13aef3e880ebd026 252 Gene3D G3DSA:3.40.50.720 1 44 3.8E-8 T 28-03-2018 CU254_RS09250 a524e73794e28bff27fc1997d6571fec 243 Gene3D G3DSA:3.20.20.70 3 243 5.6E-53 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS09250 a524e73794e28bff27fc1997d6571fec 243 TIGRFAM TIGR01919 hisA-trpF: bifunctional HisA/TrpF protein 2 243 9.9E-127 T 28-03-2018 IPR010188 Bifunctional HisA/TrpF GO:0000105|GO:0000162|GO:0003949|GO:0004640|GO:0005737 KEGG: 00340+5.3.1.16 CU254_RS09250 a524e73794e28bff27fc1997d6571fec 243 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 4 241 33.252 T 28-03-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 CU254_RS09250 a524e73794e28bff27fc1997d6571fec 243 Pfam PF00977 Histidine biosynthesis protein 5 234 2.3E-63 T 28-03-2018 IPR006062 Histidine biosynthesis GO:0000105 CU254_RS09250 a524e73794e28bff27fc1997d6571fec 243 SUPERFAMILY SSF51366 3 240 1.1E-60 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CU254_RS01580 050457ebf2be6e6afcd834a37532b354 218 Gene3D G3DSA:3.40.50.10320 4 217 2.2E-28 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CU254_RS01580 050457ebf2be6e6afcd834a37532b354 218 Pfam PF02585 GlcNAc-PI de-N-acetylase 14 126 3.6E-12 T 28-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 CU254_RS01580 050457ebf2be6e6afcd834a37532b354 218 SUPERFAMILY SSF102588 13 208 6.8E-31 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CU254_RS36605 655311db16e1116c290ae01e62da1f99 606 Pfam PF13185 GAF domain 81 224 2.5E-18 T 28-03-2018 IPR003018 GAF domain GO:0005515 CU254_RS36605 655311db16e1116c290ae01e62da1f99 606 Gene3D G3DSA:3.30.450.40 57 255 1.9E-37 T 28-03-2018 IPR029016 GAF domain-like CU254_RS36605 655311db16e1116c290ae01e62da1f99 606 Gene3D G3DSA:1.10.10.60 538 580 9.1E-4 T 28-03-2018 CU254_RS36605 655311db16e1116c290ae01e62da1f99 606 SUPERFAMILY SSF55781 65 247 9.16E-32 T 28-03-2018 IPR029016 GAF domain-like CU254_RS36605 655311db16e1116c290ae01e62da1f99 606 SMART SM00065 82 233 4.6E-24 T 28-03-2018 IPR003018 GAF domain GO:0005515 CU254_RS36605 655311db16e1116c290ae01e62da1f99 606 Pfam PF13556 PucR C-terminal helix-turn-helix domain 543 601 2.6E-16 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CU254_RS04625 9ac93cd645c6afecec96d0d86e3be498 916 Pfam PF04865 Baseplate J-like protein 671 852 9.9E-5 T 28-03-2018 IPR006949 Baseplate protein J-like CU254_RS04625 9ac93cd645c6afecec96d0d86e3be498 916 TIGRFAM TIGR02243 TIGR02243: putative baseplate assembly protein 151 870 5.3E-98 T 28-03-2018 IPR011749 Conserved hypothetical protein CHP02243 CU254_RS14600 e9da82d59c8f175ea8ea224adbc2bb67 225 Gene3D G3DSA:1.10.10.10 8 81 1.7E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS14600 e9da82d59c8f175ea8ea224adbc2bb67 225 SMART SM00895 89 208 3.2E-12 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS14600 e9da82d59c8f175ea8ea224adbc2bb67 225 Pfam PF00392 Bacterial regulatory proteins, gntR family 21 79 2.5E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS14600 e9da82d59c8f175ea8ea224adbc2bb67 225 Pfam PF07729 FCD domain 90 207 4.0E-18 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS14600 e9da82d59c8f175ea8ea224adbc2bb67 225 Gene3D G3DSA:1.20.120.530 82 223 1.8E-26 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS14600 e9da82d59c8f175ea8ea224adbc2bb67 225 SMART SM00345 21 79 3.1E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS14600 e9da82d59c8f175ea8ea224adbc2bb67 225 SUPERFAMILY SSF46785 14 83 8.44E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS14600 e9da82d59c8f175ea8ea224adbc2bb67 225 SUPERFAMILY SSF48008 85 215 4.97E-19 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS16465 366e86953cfbb9ff09a53a94a262ea4f 331 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 292 9.6E-16 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CU254_RS16465 366e86953cfbb9ff09a53a94a262ea4f 331 Pfam PF00005 ABC transporter 31 181 7.8E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS16465 366e86953cfbb9ff09a53a94a262ea4f 331 SUPERFAMILY SSF52540 4 253 3.22E-73 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS16465 366e86953cfbb9ff09a53a94a262ea4f 331 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS16465 366e86953cfbb9ff09a53a94a262ea4f 331 SMART SM00382 39 231 7.4E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS16465 366e86953cfbb9ff09a53a94a262ea4f 331 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 320 2.2E-21 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CU254_RS16465 366e86953cfbb9ff09a53a94a262ea4f 331 Gene3D G3DSA:3.40.50.300 1 328 1.5E-77 T 28-03-2018 CU254_RS01105 8ade51a95d14d7d390a5fd56500fddcf 135 SUPERFAMILY SSF55298 3 134 3.46E-22 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CU254_RS01105 8ade51a95d14d7d390a5fd56500fddcf 135 Gene3D G3DSA:3.30.1330.40 1 135 2.3E-22 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CU254_RS01105 8ade51a95d14d7d390a5fd56500fddcf 135 Pfam PF01042 Endoribonuclease L-PSP 13 133 1.3E-14 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family CU254_RS14250 0578b7a57e396fcfd4cc065ba15a2600 216 Gene3D G3DSA:1.10.1740.10 25 119 9.8E-15 T 28-03-2018 CU254_RS14250 0578b7a57e396fcfd4cc065ba15a2600 216 Pfam PF08281 Sigma-70, region 4 151 201 2.2E-13 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS14250 0578b7a57e396fcfd4cc065ba15a2600 216 SUPERFAMILY SSF88946 29 136 3.66E-12 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS14250 0578b7a57e396fcfd4cc065ba15a2600 216 SUPERFAMILY SSF88659 133 210 1.14E-12 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS14250 0578b7a57e396fcfd4cc065ba15a2600 216 Gene3D G3DSA:1.10.10.10 120 208 6.1E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS14250 0578b7a57e396fcfd4cc065ba15a2600 216 Pfam PF04542 Sigma-70 region 2 51 118 5.9E-8 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS14250 0578b7a57e396fcfd4cc065ba15a2600 216 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 47 203 1.2E-20 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS38615 bf6a567a60c51634e77821a7180f5242 371 Gene3D G3DSA:3.40.50.150 8 171 2.3E-38 T 28-03-2018 CU254_RS38615 bf6a567a60c51634e77821a7180f5242 371 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 8 24 4.0E-10 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CU254_RS38615 bf6a567a60c51634e77821a7180f5242 371 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 161 174 4.0E-10 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CU254_RS38615 bf6a567a60c51634e77821a7180f5242 371 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 116 130 4.0E-10 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CU254_RS38615 bf6a567a60c51634e77821a7180f5242 371 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 10 354 1.3E-37 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CU254_RS38615 bf6a567a60c51634e77821a7180f5242 371 Pfam PF00145 C-5 cytosine-specific DNA methylase 10 354 2.1E-39 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS38615 bf6a567a60c51634e77821a7180f5242 371 Gene3D G3DSA:3.90.120.10 172 347 1.5E-9 T 28-03-2018 CU254_RS38615 bf6a567a60c51634e77821a7180f5242 371 SUPERFAMILY SSF53335 9 353 6.64E-61 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS12740 1ede76ed756219d9e7edb3098dc38d2c 450 PIRSF PIRSF001386 1 450 3.3E-165 T 28-03-2018 IPR011166 Beta-eliminating lyase family GO:0009072|GO:0016830 KEGG: 00380+4.1.99.1 CU254_RS12740 1ede76ed756219d9e7edb3098dc38d2c 450 Pfam PF01212 Beta-eliminating lyase 42 415 4.0E-73 T 28-03-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 CU254_RS12740 1ede76ed756219d9e7edb3098dc38d2c 450 SUPERFAMILY SSF53383 2 448 5.89E-106 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS12740 1ede76ed756219d9e7edb3098dc38d2c 450 Gene3D G3DSA:3.90.1150.10 264 447 4.3E-64 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS12740 1ede76ed756219d9e7edb3098dc38d2c 450 Gene3D G3DSA:3.90.1150.10 14 133 2.8E-21 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS06620 5e812f32f0a3c8a399d8daff0854ef91 365 SUPERFAMILY SSF53955 85 218 9.28E-11 T 28-03-2018 IPR023346 Lysozyme-like domain CU254_RS06620 5e812f32f0a3c8a399d8daff0854ef91 365 Gene3D G3DSA:3.90.1720.10 234 360 1.3E-28 T 28-03-2018 CU254_RS06620 5e812f32f0a3c8a399d8daff0854ef91 365 SUPERFAMILY SSF54001 242 351 6.87E-31 T 28-03-2018 CU254_RS06620 5e812f32f0a3c8a399d8daff0854ef91 365 Pfam PF00877 NlpC/P60 family 257 352 2.3E-23 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CU254_RS06620 5e812f32f0a3c8a399d8daff0854ef91 365 Gene3D G3DSA:1.10.530.10 74 229 7.0E-11 T 28-03-2018 CU254_RS02490 690f1077541d4ba95a104ffc18021d32 430 Pfam PF09922 Cell wall-active antibiotics response 4TMS YvqF 332 427 4.3E-10 T 28-03-2018 IPR024425 Cell wall-active antibiotics response 4TMS YvqF CU254_RS02490 690f1077541d4ba95a104ffc18021d32 430 Pfam PF04024 PspC domain 31 84 4.5E-12 T 28-03-2018 IPR007168 Phage shock protein, PspC, N-terminal CU254_RS30530 c3528d66de6857b3baf9b8ab581842f1 537 SUPERFAMILY SSF52540 273 511 1.98E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS30530 c3528d66de6857b3baf9b8ab581842f1 537 ProSitePatterns PS00211 ABC transporters family signature. 412 426 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS30530 c3528d66de6857b3baf9b8ab581842f1 537 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 229 261 0.0022 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CU254_RS30530 c3528d66de6857b3baf9b8ab581842f1 537 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 491 532 4.5E-7 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CU254_RS30530 c3528d66de6857b3baf9b8ab581842f1 537 Pfam PF00005 ABC transporter 289 440 6.9E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS30530 c3528d66de6857b3baf9b8ab581842f1 537 Pfam PF00005 ABC transporter 19 177 1.9E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS30530 c3528d66de6857b3baf9b8ab581842f1 537 Gene3D G3DSA:3.40.50.300 1 267 1.3E-68 T 28-03-2018 CU254_RS30530 c3528d66de6857b3baf9b8ab581842f1 537 Gene3D G3DSA:3.40.50.300 269 536 6.1E-77 T 28-03-2018 CU254_RS30530 c3528d66de6857b3baf9b8ab581842f1 537 SMART SM00382 27 227 2.6E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS30530 c3528d66de6857b3baf9b8ab581842f1 537 SMART SM00382 297 488 5.0E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS30530 c3528d66de6857b3baf9b8ab581842f1 537 SUPERFAMILY SSF52540 1 249 1.33E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS21860 3d4f8706869c49cfdb970dc7ed0792f0 356 Pfam PF06032 Protein of unknown function (DUF917) 7 352 7.0E-90 T 28-03-2018 IPR010318 Protein of unknown function DUF917 CU254_RS21860 3d4f8706869c49cfdb970dc7ed0792f0 356 SUPERFAMILY SSF160991 2 354 3.53E-86 T 28-03-2018 CU254_RS21860 3d4f8706869c49cfdb970dc7ed0792f0 356 Gene3D G3DSA:2.40.390.10 219 343 1.6E-26 T 28-03-2018 IPR024071 Protein of unknown function DUF917, C-terminal CU254_RS21860 3d4f8706869c49cfdb970dc7ed0792f0 356 Gene3D G3DSA:3.40.1610.10 1 218 1.9E-55 T 28-03-2018 IPR027479 Protein of unknown function DUF917, N-terminal CU254_RS06385 eaf8dab7531374820f6532e24dd4a1f6 543 Pfam PF00474 Sodium:solute symporter family 44 454 2.1E-94 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CU254_RS06385 eaf8dab7531374820f6532e24dd4a1f6 543 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 44 453 5.9E-59 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CU254_RS24450 b447b7290bc1235aa1c93853720a9a0e 525 Pfam PF05223 NTF2-like N-terminal transpeptidase domain 44 152 5.5E-14 T 28-03-2018 IPR007887 NTF2-like N-terminal transpeptidase GO:0046677 CU254_RS24450 b447b7290bc1235aa1c93853720a9a0e 525 Pfam PF00905 Penicillin binding protein transpeptidase domain 256 512 1.0E-38 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CU254_RS24450 b447b7290bc1235aa1c93853720a9a0e 525 SUPERFAMILY SSF56601 237 517 5.29E-56 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CU254_RS24450 b447b7290bc1235aa1c93853720a9a0e 525 Gene3D G3DSA:3.40.710.10 229 524 7.1E-55 T 28-03-2018 CU254_RS24450 b447b7290bc1235aa1c93853720a9a0e 525 Gene3D G3DSA:3.10.450.100 41 147 1.1E-9 T 28-03-2018 CU254_RS13405 be39b399150314ae76c89633200c95db 263 TIGRFAM TIGR03704 PrmC_rel_meth: putative protein-(glutamine-N5) methyltransferase, unknown substrate-specific 19 259 5.9E-113 T 28-03-2018 IPR022446 Conserved hypothetical protein CHP03704, protein-(glutamine-N5) methyltransferase CU254_RS13405 be39b399150314ae76c89633200c95db 263 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 44 246 1.1E-42 T 28-03-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 CU254_RS13405 be39b399150314ae76c89633200c95db 263 Gene3D G3DSA:3.40.50.150 70 261 9.3E-36 T 28-03-2018 CU254_RS13405 be39b399150314ae76c89633200c95db 263 Gene3D G3DSA:1.10.8.10 16 69 5.2E-8 T 28-03-2018 CU254_RS13405 be39b399150314ae76c89633200c95db 263 Pfam PF05175 Methyltransferase small domain 75 173 5.2E-11 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 CU254_RS13405 be39b399150314ae76c89633200c95db 263 SUPERFAMILY SSF53335 52 226 2.2E-44 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS27715 81f60c1f17ab73fb0ca74a78d4079e1b 774 Pfam PF13560 Helix-turn-helix domain 26 88 8.2E-17 T 28-03-2018 CU254_RS27715 81f60c1f17ab73fb0ca74a78d4079e1b 774 SMART SM00530 29 85 8.9E-17 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS27715 81f60c1f17ab73fb0ca74a78d4079e1b 774 Gene3D G3DSA:1.10.260.40 18 103 6.6E-18 T 28-03-2018 CU254_RS27715 81f60c1f17ab73fb0ca74a78d4079e1b 774 SUPERFAMILY SSF47413 26 84 7.88E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS27715 81f60c1f17ab73fb0ca74a78d4079e1b 774 Gene3D G3DSA:3.40.50.300 166 321 9.2E-4 T 28-03-2018 CU254_RS27715 81f60c1f17ab73fb0ca74a78d4079e1b 774 Pfam PF05729 NACHT domain 195 345 3.5E-6 T 28-03-2018 CU254_RS01440 367a994371871ae64e640a3911889194 640 SUPERFAMILY SSF53323 31 239 4.05E-17 T 28-03-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CU254_RS01440 367a994371871ae64e640a3911889194 640 SUPERFAMILY SSF52922 532 634 3.4E-11 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CU254_RS01440 367a994371871ae64e640a3911889194 640 Gene3D G3DSA:3.40.50.970 248 517 1.3E-54 T 28-03-2018 CU254_RS01440 367a994371871ae64e640a3911889194 640 Gene3D G3DSA:3.40.50.920 529 633 6.4E-5 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CU254_RS01440 367a994371871ae64e640a3911889194 640 Gene3D G3DSA:3.40.920.10 26 242 2.1E-42 T 28-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CU254_RS01440 367a994371871ae64e640a3911889194 640 SUPERFAMILY SSF52518 249 515 5.74E-60 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS01440 367a994371871ae64e640a3911889194 640 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 37 225 4.7E-26 T 28-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CU254_RS01440 367a994371871ae64e640a3911889194 640 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 278 492 4.3E-51 T 28-03-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 CU254_RS01440 367a994371871ae64e640a3911889194 640 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 29 625 2.4E-199 T 28-03-2018 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 CU254_RS29240 388cc85e4c8b7f0cb8b64d9186e77951 536 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 174 7.4E-45 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CU254_RS29240 388cc85e4c8b7f0cb8b64d9186e77951 536 SUPERFAMILY SSF52467 187 341 3.74E-28 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CU254_RS29240 388cc85e4c8b7f0cb8b64d9186e77951 536 Gene3D G3DSA:3.40.50.1220 195 340 6.4E-28 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CU254_RS29240 388cc85e4c8b7f0cb8b64d9186e77951 536 Gene3D G3DSA:3.40.50.970 1 194 7.2E-45 T 28-03-2018 CU254_RS29240 388cc85e4c8b7f0cb8b64d9186e77951 536 Gene3D G3DSA:3.40.50.970 341 528 7.1E-31 T 28-03-2018 CU254_RS29240 388cc85e4c8b7f0cb8b64d9186e77951 536 SUPERFAMILY SSF52518 353 532 8.4E-45 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS29240 388cc85e4c8b7f0cb8b64d9186e77951 536 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 383 520 5.1E-30 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CU254_RS29240 388cc85e4c8b7f0cb8b64d9186e77951 536 SUPERFAMILY SSF52518 3 181 3.94E-42 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS29240 388cc85e4c8b7f0cb8b64d9186e77951 536 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 196 321 2.7E-16 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CU254_RS23210 071dfd87f985703d7dde388c69d04bf9 248 Gene3D G3DSA:1.10.3300.10 69 248 3.2E-31 T 28-03-2018 IPR023286 ABATE domain CU254_RS23210 071dfd87f985703d7dde388c69d04bf9 248 Pfam PF11706 CGNR zinc finger 204 246 2.7E-14 T 28-03-2018 IPR021005 Zinc finger, CGNR CU254_RS23210 071dfd87f985703d7dde388c69d04bf9 248 SUPERFAMILY SSF160904 72 245 2.09E-33 T 28-03-2018 CU254_RS20335 0c0e852c5885e34755034e4e7ffde7d7 353 SUPERFAMILY SSF51735 155 312 4.74E-21 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS20335 0c0e852c5885e34755034e4e7ffde7d7 353 SUPERFAMILY SSF50129 2 183 1.83E-25 T 28-03-2018 IPR011032 GroES-like CU254_RS20335 0c0e852c5885e34755034e4e7ffde7d7 353 Gene3D G3DSA:3.40.50.720 167 319 9.4E-21 T 28-03-2018 CU254_RS20335 0c0e852c5885e34755034e4e7ffde7d7 353 Gene3D G3DSA:3.90.180.10 1 166 2.3E-27 T 28-03-2018 CU254_RS20335 0c0e852c5885e34755034e4e7ffde7d7 353 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 137 1.1E-7 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CU254_RS12110 9da9533efbc80c37e15947d1e465f807 341 Gene3D G3DSA:1.10.10.10 79 182 2.1E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS12110 9da9533efbc80c37e15947d1e465f807 341 Gene3D G3DSA:1.25.40.10 187 339 2.4E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS12110 9da9533efbc80c37e15947d1e465f807 341 Pfam PF00486 Transcriptional regulatory protein, C terminal 113 175 1.3E-6 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS12110 9da9533efbc80c37e15947d1e465f807 341 Pfam PF03704 Bacterial transcriptional activator domain 189 322 1.3E-14 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CU254_RS12110 9da9533efbc80c37e15947d1e465f807 341 SUPERFAMILY SSF46894 91 175 7.94E-9 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS12110 9da9533efbc80c37e15947d1e465f807 341 SUPERFAMILY SSF48452 188 322 1.01E-16 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS12110 9da9533efbc80c37e15947d1e465f807 341 SMART SM01043 189 327 1.3E-23 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CU254_RS25620 f3c6dc44f5cf32e9c83b2a7316c6534a 288 Pfam PF04072 Leucine carboxyl methyltransferase 13 191 9.9E-46 T 28-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CU254_RS25620 f3c6dc44f5cf32e9c83b2a7316c6534a 288 Gene3D G3DSA:3.40.50.150 6 279 1.1E-38 T 28-03-2018 CU254_RS25620 f3c6dc44f5cf32e9c83b2a7316c6534a 288 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 7 268 5.5E-73 T 28-03-2018 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 CU254_RS25620 f3c6dc44f5cf32e9c83b2a7316c6534a 288 SUPERFAMILY SSF53335 6 284 4.43E-61 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS22415 00b4793f44a9ebc3bf89eb7eac5d9e8b 424 SUPERFAMILY SSF55174 341 420 1.06E-13 T 28-03-2018 CU254_RS22415 00b4793f44a9ebc3bf89eb7eac5d9e8b 424 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 4 420 2.5E-109 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CU254_RS22415 00b4793f44a9ebc3bf89eb7eac5d9e8b 424 Pfam PF00579 tRNA synthetases class I (W and Y) 31 325 4.0E-78 T 28-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 CU254_RS22415 00b4793f44a9ebc3bf89eb7eac5d9e8b 424 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 163 178 3.9E-27 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CU254_RS22415 00b4793f44a9ebc3bf89eb7eac5d9e8b 424 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 45 67 3.9E-27 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CU254_RS22415 00b4793f44a9ebc3bf89eb7eac5d9e8b 424 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 184 206 3.9E-27 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CU254_RS22415 00b4793f44a9ebc3bf89eb7eac5d9e8b 424 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 217 229 3.9E-27 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CU254_RS22415 00b4793f44a9ebc3bf89eb7eac5d9e8b 424 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 3 422 43.261 T 28-03-2018 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 CU254_RS22415 00b4793f44a9ebc3bf89eb7eac5d9e8b 424 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 41 51 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CU254_RS22415 00b4793f44a9ebc3bf89eb7eac5d9e8b 424 Gene3D G3DSA:3.40.50.620 1 230 2.2E-60 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS22415 00b4793f44a9ebc3bf89eb7eac5d9e8b 424 Gene3D G3DSA:1.10.240.10 231 326 6.3E-30 T 28-03-2018 CU254_RS22415 00b4793f44a9ebc3bf89eb7eac5d9e8b 424 Gene3D G3DSA:3.10.290.10 327 423 2.4E-19 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CU254_RS22415 00b4793f44a9ebc3bf89eb7eac5d9e8b 424 SUPERFAMILY SSF52374 4 325 3.15E-97 T 28-03-2018 CU254_RS26350 9f19f918b59df02af34392dc0a934ec5 303 Gene3D G3DSA:3.40.50.300 4 266 3.2E-64 T 28-03-2018 CU254_RS26350 9f19f918b59df02af34392dc0a934ec5 303 SMART SM00382 31 207 1.6E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS26350 9f19f918b59df02af34392dc0a934ec5 303 SUPERFAMILY SSF52540 5 223 1.09E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS26350 9f19f918b59df02af34392dc0a934ec5 303 Pfam PF00005 ABC transporter 23 159 7.2E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS26350 9f19f918b59df02af34392dc0a934ec5 303 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS12935 37b7f372f8f2f6cfb3dcd587d8b998b9 453 Gene3D G3DSA:3.50.50.60 386 453 9.3E-7 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS12935 37b7f372f8f2f6cfb3dcd587d8b998b9 453 PRINTS PR00757 Flavin-containing amine oxidase signature 198 220 2.2E-38 T 28-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 CU254_RS12935 37b7f372f8f2f6cfb3dcd587d8b998b9 453 PRINTS PR00757 Flavin-containing amine oxidase signature 428 445 2.2E-38 T 28-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 CU254_RS12935 37b7f372f8f2f6cfb3dcd587d8b998b9 453 PRINTS PR00757 Flavin-containing amine oxidase signature 5 24 2.2E-38 T 28-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 CU254_RS12935 37b7f372f8f2f6cfb3dcd587d8b998b9 453 PRINTS PR00757 Flavin-containing amine oxidase signature 93 115 2.2E-38 T 28-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 CU254_RS12935 37b7f372f8f2f6cfb3dcd587d8b998b9 453 PRINTS PR00757 Flavin-containing amine oxidase signature 397 419 2.2E-38 T 28-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 CU254_RS12935 37b7f372f8f2f6cfb3dcd587d8b998b9 453 PRINTS PR00757 Flavin-containing amine oxidase signature 376 395 2.2E-38 T 28-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 CU254_RS12935 37b7f372f8f2f6cfb3dcd587d8b998b9 453 PRINTS PR00757 Flavin-containing amine oxidase signature 293 312 2.2E-38 T 28-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 CU254_RS12935 37b7f372f8f2f6cfb3dcd587d8b998b9 453 Gene3D G3DSA:3.50.50.60 2 73 9.2E-7 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS12935 37b7f372f8f2f6cfb3dcd587d8b998b9 453 SUPERFAMILY SSF51905 410 448 1.26E-71 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS12935 37b7f372f8f2f6cfb3dcd587d8b998b9 453 SUPERFAMILY SSF51905 1 308 1.26E-71 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS12935 37b7f372f8f2f6cfb3dcd587d8b998b9 453 Gene3D G3DSA:3.90.660.10 227 385 3.2E-42 T 28-03-2018 CU254_RS12935 37b7f372f8f2f6cfb3dcd587d8b998b9 453 Pfam PF01593 Flavin containing amine oxidoreductase 13 447 2.3E-73 T 28-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 CU254_RS12935 37b7f372f8f2f6cfb3dcd587d8b998b9 453 Gene3D G3DSA:1.10.405.10 110 199 1.7E-22 T 28-03-2018 CU254_RS12935 37b7f372f8f2f6cfb3dcd587d8b998b9 453 SUPERFAMILY SSF54373 290 396 3.21E-34 T 28-03-2018 CU254_RS14340 010dbc1f9dc97671a7c427b0c32279f7 479 SUPERFAMILY SSF53448 79 313 1.21E-47 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS14340 010dbc1f9dc97671a7c427b0c32279f7 479 TIGRFAM TIGR03965 mycofact_glyco: mycofactocin system glycosyltransferase 12 467 4.2E-111 T 28-03-2018 IPR023981 Putative mycofactocin biosynthesis glycosyltransferase CU254_RS14340 010dbc1f9dc97671a7c427b0c32279f7 479 Pfam PF00535 Glycosyl transferase family 2 86 244 1.1E-23 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CU254_RS14340 010dbc1f9dc97671a7c427b0c32279f7 479 Gene3D G3DSA:3.90.550.10 54 312 5.1E-47 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS19355 bcd248081524009a1cc6d163067e8e1b 539 Gene3D G3DSA:3.30.300.30 430 537 6.8E-23 T 28-03-2018 CU254_RS19355 bcd248081524009a1cc6d163067e8e1b 539 Gene3D G3DSA:3.40.50.980 18 192 1.6E-31 T 28-03-2018 CU254_RS19355 bcd248081524009a1cc6d163067e8e1b 539 Gene3D G3DSA:2.30.38.10 345 428 7.3E-24 T 28-03-2018 CU254_RS19355 bcd248081524009a1cc6d163067e8e1b 539 SUPERFAMILY SSF56801 19 531 1.44E-128 T 28-03-2018 CU254_RS19355 bcd248081524009a1cc6d163067e8e1b 539 Pfam PF00501 AMP-binding enzyme 29 435 2.4E-75 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS19355 bcd248081524009a1cc6d163067e8e1b 539 Pfam PF13193 AMP-binding enzyme C-terminal domain 444 518 1.0E-8 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS19355 bcd248081524009a1cc6d163067e8e1b 539 Gene3D G3DSA:3.40.50.980 193 344 5.1E-32 T 28-03-2018 CU254_RS04590 e4dfa0141bc8af894076aa7a95007f60 605 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 398 522 1.4E-24 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CU254_RS04590 e4dfa0141bc8af894076aa7a95007f60 605 SMART SM00382 394 524 1.0E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS04590 e4dfa0141bc8af894076aa7a95007f60 605 Gene3D G3DSA:3.40.50.300 348 534 3.0E-30 T 28-03-2018 CU254_RS04590 e4dfa0141bc8af894076aa7a95007f60 605 SUPERFAMILY SSF52540 356 584 9.21E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS37295 e17b361b16325a571a4762ba3f4dae27 264 SUPERFAMILY SSF53335 8 255 5.54E-66 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS37295 e17b361b16325a571a4762ba3f4dae27 264 Gene3D G3DSA:3.40.50.150 7 254 1.5E-51 T 28-03-2018 CU254_RS37295 e17b361b16325a571a4762ba3f4dae27 264 Pfam PF04072 Leucine carboxyl methyltransferase 12 178 1.4E-51 T 28-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CU254_RS37295 e17b361b16325a571a4762ba3f4dae27 264 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 9 249 2.4E-76 T 28-03-2018 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 CU254_RS06410 44f59cfea782016dd88779898e4b2251 349 PRINTS PR00344 Bacterial sensor protein C-terminal signature 301 319 1.7E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS06410 44f59cfea782016dd88779898e4b2251 349 PRINTS PR00344 Bacterial sensor protein C-terminal signature 276 290 1.7E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS06410 44f59cfea782016dd88779898e4b2251 349 PRINTS PR00344 Bacterial sensor protein C-terminal signature 328 341 1.7E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS06410 44f59cfea782016dd88779898e4b2251 349 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 243 341 5.4E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS06410 44f59cfea782016dd88779898e4b2251 349 SMART SM00387 235 344 3.8E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS06410 44f59cfea782016dd88779898e4b2251 349 Gene3D G3DSA:3.30.565.10 117 342 3.3E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS06410 44f59cfea782016dd88779898e4b2251 349 Pfam PF06580 Histidine kinase 146 224 3.5E-19 T 28-03-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 CU254_RS06410 44f59cfea782016dd88779898e4b2251 349 SUPERFAMILY SSF55874 204 341 1.31E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS12780 fa33602bc754ea6473ba9aac3ae7f692 159 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 145 1.7E-14 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CU254_RS12780 fa33602bc754ea6473ba9aac3ae7f692 159 SUPERFAMILY SSF54593 1 148 1.48E-26 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS12780 fa33602bc754ea6473ba9aac3ae7f692 159 Gene3D G3DSA:3.10.180.10 1 158 3.5E-28 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS22180 e74c52b41eba14f68325cf771bffbb8a 418 SMART SM00922 167 261 8.6E-20 T 28-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CU254_RS22180 e74c52b41eba14f68325cf771bffbb8a 418 Pfam PF13378 Enolase C-terminal domain-like 172 381 1.7E-47 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CU254_RS22180 e74c52b41eba14f68325cf771bffbb8a 418 SUPERFAMILY SSF54826 1 133 3.01E-22 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CU254_RS22180 e74c52b41eba14f68325cf771bffbb8a 418 SUPERFAMILY SSF51604 133 390 6.81E-69 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CU254_RS22180 e74c52b41eba14f68325cf771bffbb8a 418 Gene3D G3DSA:3.20.20.120 141 390 3.4E-52 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CU254_RS22180 e74c52b41eba14f68325cf771bffbb8a 418 Gene3D G3DSA:3.30.390.10 1 140 6.5E-31 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CU254_RS22180 e74c52b41eba14f68325cf771bffbb8a 418 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 32 133 9.1E-7 T 28-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CU254_RS20915 dd6a9e57e2464ac4dbba244a6d7c1a0c 284 SMART SM00849 45 261 2.5E-17 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS20915 dd6a9e57e2464ac4dbba244a6d7c1a0c 284 Gene3D G3DSA:3.60.15.10 3 271 1.0E-39 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS20915 dd6a9e57e2464ac4dbba244a6d7c1a0c 284 Pfam PF00753 Metallo-beta-lactamase superfamily 45 261 6.1E-19 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS20915 dd6a9e57e2464ac4dbba244a6d7c1a0c 284 SUPERFAMILY SSF56281 40 269 1.7E-35 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS03275 3e039adc499cc2802f72960bd4e9b740 545 Gene3D G3DSA:3.90.226.10 279 536 2.2E-73 T 28-03-2018 CU254_RS03275 3e039adc499cc2802f72960bd4e9b740 545 SUPERFAMILY SSF52096 24 274 1.24E-77 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS03275 3e039adc499cc2802f72960bd4e9b740 545 SUPERFAMILY SSF52096 261 545 3.15E-88 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS03275 3e039adc499cc2802f72960bd4e9b740 545 Pfam PF01039 Carboxyl transferase domain 46 543 2.4E-200 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 CU254_RS03275 3e039adc499cc2802f72960bd4e9b740 545 Gene3D G3DSA:3.90.226.10 12 276 9.4E-80 T 28-03-2018 CU254_RS25145 8b6c5485a0b6aef6f97747da9d02e4ae 182 Pfam PF06353 Protein of unknown function (DUF1062) 35 165 5.5E-39 T 28-03-2018 IPR009412 Protein of unknown function DUF1062 CU254_RS38265 ccc7ecb46165753c5e9a240635944fe8 864 SMART SM00382 199 345 8.6E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS38265 ccc7ecb46165753c5e9a240635944fe8 864 SMART SM00382 601 751 2.5E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS38265 ccc7ecb46165753c5e9a240635944fe8 864 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 204 322 1.5E-11 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CU254_RS38265 ccc7ecb46165753c5e9a240635944fe8 864 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 95 146 3.1E-14 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CU254_RS38265 ccc7ecb46165753c5e9a240635944fe8 864 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 65 8.9E-9 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CU254_RS38265 ccc7ecb46165753c5e9a240635944fe8 864 SUPERFAMILY SSF81923 7 157 8.63E-33 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CU254_RS38265 ccc7ecb46165753c5e9a240635944fe8 864 SMART SM01086 768 853 6.1E-35 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CU254_RS38265 ccc7ecb46165753c5e9a240635944fe8 864 Pfam PF07724 AAA domain (Cdc48 subfamily) 600 762 2.8E-54 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CU254_RS38265 ccc7ecb46165753c5e9a240635944fe8 864 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 296 308 - T 28-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 CU254_RS38265 ccc7ecb46165753c5e9a240635944fe8 864 SUPERFAMILY SSF52540 158 549 3.8E-96 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS38265 ccc7ecb46165753c5e9a240635944fe8 864 Gene3D G3DSA:3.40.50.300 556 767 5.1E-53 T 28-03-2018 CU254_RS38265 ccc7ecb46165753c5e9a240635944fe8 864 Gene3D G3DSA:3.40.50.300 158 344 1.7E-23 T 28-03-2018 CU254_RS38265 ccc7ecb46165753c5e9a240635944fe8 864 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 7 851 0.0 T 28-03-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0016485 CU254_RS38265 ccc7ecb46165753c5e9a240635944fe8 864 Gene3D G3DSA:1.10.1780.10 5 152 2.5E-32 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CU254_RS38265 ccc7ecb46165753c5e9a240635944fe8 864 Gene3D G3DSA:1.10.8.60 346 551 4.9E-45 T 28-03-2018 CU254_RS38265 ccc7ecb46165753c5e9a240635944fe8 864 Gene3D G3DSA:1.10.8.60 768 863 1.3E-24 T 28-03-2018 CU254_RS38265 ccc7ecb46165753c5e9a240635944fe8 864 SUPERFAMILY SSF52540 550 852 6.26E-78 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS38265 ccc7ecb46165753c5e9a240635944fe8 864 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 768 848 1.7E-26 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CU254_RS38265 ccc7ecb46165753c5e9a240635944fe8 864 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 712 726 4.7E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CU254_RS38265 ccc7ecb46165753c5e9a240635944fe8 864 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 679 697 4.7E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CU254_RS38265 ccc7ecb46165753c5e9a240635944fe8 864 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 605 623 4.7E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CU254_RS38265 ccc7ecb46165753c5e9a240635944fe8 864 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 650 668 4.7E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CU254_RS38265 ccc7ecb46165753c5e9a240635944fe8 864 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 635 653 - T 28-03-2018 IPR028299 ClpA/B, conserved site 2 CU254_RS23895 4dbcb556b70f9dd3e7b9de4d38989f4e 302 Gene3D G3DSA:3.40.50.720 2 262 8.9E-62 T 28-03-2018 CU254_RS23895 4dbcb556b70f9dd3e7b9de4d38989f4e 302 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 161 5.2E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23895 4dbcb556b70f9dd3e7b9de4d38989f4e 302 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 190 5.2E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23895 4dbcb556b70f9dd3e7b9de4d38989f4e 302 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 192 209 5.2E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23895 4dbcb556b70f9dd3e7b9de4d38989f4e 302 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 5.2E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23895 4dbcb556b70f9dd3e7b9de4d38989f4e 302 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 5.2E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23895 4dbcb556b70f9dd3e7b9de4d38989f4e 302 Pfam PF00106 short chain dehydrogenase 9 207 1.1E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23895 4dbcb556b70f9dd3e7b9de4d38989f4e 302 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 202 0.0011 T 28-03-2018 CU254_RS23895 4dbcb556b70f9dd3e7b9de4d38989f4e 302 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 158 186 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS23895 4dbcb556b70f9dd3e7b9de4d38989f4e 302 SUPERFAMILY SSF51735 5 260 4.26E-61 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS23895 4dbcb556b70f9dd3e7b9de4d38989f4e 302 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 171 190 2.5E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23895 4dbcb556b70f9dd3e7b9de4d38989f4e 302 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 159 2.5E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23895 4dbcb556b70f9dd3e7b9de4d38989f4e 302 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 92 103 2.5E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23830 483229df4db1bf54ef9ab2952d753426 291 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 83 1.9E-5 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CU254_RS23830 483229df4db1bf54ef9ab2952d753426 291 Gene3D G3DSA:3.90.180.10 223 291 0.0025 T 28-03-2018 CU254_RS23830 483229df4db1bf54ef9ab2952d753426 291 Gene3D G3DSA:3.90.180.10 1 138 1.9E-36 T 28-03-2018 CU254_RS23830 483229df4db1bf54ef9ab2952d753426 291 SUPERFAMILY SSF50129 2 149 6.54E-31 T 28-03-2018 IPR011032 GroES-like CU254_RS23830 483229df4db1bf54ef9ab2952d753426 291 SUPERFAMILY SSF51735 113 230 2.63E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS23830 483229df4db1bf54ef9ab2952d753426 291 Gene3D G3DSA:3.40.50.720 139 222 1.5E-25 T 28-03-2018 CU254_RS23830 483229df4db1bf54ef9ab2952d753426 291 Pfam PF13602 Zinc-binding dehydrogenase 182 288 3.9E-19 T 28-03-2018 CU254_RS23830 483229df4db1bf54ef9ab2952d753426 291 SMART SM00829 10 288 1.9E-22 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CU254_RS23830 483229df4db1bf54ef9ab2952d753426 291 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 140 161 - T 28-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 CU254_RS42235 3930828c6b6e50264a727ed1f16ab9ae 259 Gene3D G3DSA:3.40.50.300 129 238 6.2E-10 T 28-03-2018 CU254_RS42235 3930828c6b6e50264a727ed1f16ab9ae 259 SUPERFAMILY SSF52540 45 229 5.82E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS42235 3930828c6b6e50264a727ed1f16ab9ae 259 Pfam PF13476 AAA domain 45 82 5.1E-8 T 28-03-2018 CU254_RS42235 3930828c6b6e50264a727ed1f16ab9ae 259 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 166 212 8.2E-8 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CU254_RS42235 3930828c6b6e50264a727ed1f16ab9ae 259 Gene3D G3DSA:3.40.50.300 38 128 3.3E-8 T 28-03-2018 CU254_RS42235 3930828c6b6e50264a727ed1f16ab9ae 259 SMART SM00382 48 233 2.3E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS33505 dcc3b1cb1a0195888e9c57f5090d5846 478 Gene3D G3DSA:3.40.50.1820 1 445 9.4E-44 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS33505 dcc3b1cb1a0195888e9c57f5090d5846 478 SUPERFAMILY SSF53474 344 421 2.08E-24 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS33505 dcc3b1cb1a0195888e9c57f5090d5846 478 SUPERFAMILY SSF53474 147 201 2.08E-24 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS33505 dcc3b1cb1a0195888e9c57f5090d5846 478 SUPERFAMILY SSF53474 47 103 2.08E-24 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS33505 dcc3b1cb1a0195888e9c57f5090d5846 478 Pfam PF00561 alpha/beta hydrolase fold 51 420 3.0E-26 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS16250 38b67cf05395a85de4a601848fcdc963 122 Gene3D G3DSA:1.10.10.10 3 122 7.1E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS16250 38b67cf05395a85de4a601848fcdc963 122 Pfam PF01638 HxlR-like helix-turn-helix 21 108 4.7E-24 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type CU254_RS16250 38b67cf05395a85de4a601848fcdc963 122 SUPERFAMILY SSF46785 6 117 1.87E-33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS08630 08b6e16d329ef39677543a33224dd3e6 204 Gene3D G3DSA:1.20.120.530 71 204 1.3E-22 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS08630 08b6e16d329ef39677543a33224dd3e6 204 Pfam PF07729 FCD domain 88 191 5.6E-15 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS08630 08b6e16d329ef39677543a33224dd3e6 204 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 68 7.7E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS08630 08b6e16d329ef39677543a33224dd3e6 204 SMART SM00895 78 196 0.0068 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS08630 08b6e16d329ef39677543a33224dd3e6 204 SMART SM00345 10 68 4.4E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS08630 08b6e16d329ef39677543a33224dd3e6 204 Gene3D G3DSA:1.10.10.10 3 70 2.8E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS08630 08b6e16d329ef39677543a33224dd3e6 204 SUPERFAMILY SSF46785 10 72 4.75E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS08630 08b6e16d329ef39677543a33224dd3e6 204 SUPERFAMILY SSF48008 75 201 3.4E-17 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS30255 3e76c56604b904ea69a51e114a4fe2e8 415 Gene3D G3DSA:3.30.559.10 182 415 1.7E-77 T 28-03-2018 CU254_RS30255 3e76c56604b904ea69a51e114a4fe2e8 415 Gene3D G3DSA:2.40.50.100 1 81 4.4E-15 T 28-03-2018 CU254_RS30255 3e76c56604b904ea69a51e114a4fe2e8 415 Pfam PF02817 e3 binding domain 138 171 5.7E-12 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CU254_RS30255 3e76c56604b904ea69a51e114a4fe2e8 415 Pfam PF00364 Biotin-requiring enzyme 3 74 5.4E-18 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CU254_RS30255 3e76c56604b904ea69a51e114a4fe2e8 415 SUPERFAMILY SSF47005 131 175 3.27E-10 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CU254_RS30255 3e76c56604b904ea69a51e114a4fe2e8 415 Gene3D G3DSA:4.10.320.10 126 181 5.7E-16 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CU254_RS30255 3e76c56604b904ea69a51e114a4fe2e8 415 SUPERFAMILY SSF51230 3 79 4.06E-22 T 28-03-2018 IPR011053 Single hybrid motif CU254_RS30255 3e76c56604b904ea69a51e114a4fe2e8 415 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 188 412 1.0E-73 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CU254_RS30255 3e76c56604b904ea69a51e114a4fe2e8 415 SUPERFAMILY SSF52777 188 412 3.74E-72 T 28-03-2018 CU254_RS30255 3e76c56604b904ea69a51e114a4fe2e8 415 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 26 55 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CU254_RS10215 c01ce4769e77161b4928711c7e5b8c95 310 Pfam PF13406 Transglycosylase SLT domain 223 267 5.6E-9 T 28-03-2018 IPR031304 Transglycosylase SLT domain 2 CU254_RS10215 c01ce4769e77161b4928711c7e5b8c95 310 SUPERFAMILY SSF53955 126 301 5.18E-37 T 28-03-2018 IPR023346 Lysozyme-like domain CU254_RS10215 c01ce4769e77161b4928711c7e5b8c95 310 Gene3D G3DSA:1.10.530.10 113 309 1.2E-29 T 28-03-2018 CU254_RS10025 702e90eaeaa8f7d9c42ccdc465b541c3 264 Pfam PF00149 Calcineurin-like phosphoesterase 2 235 1.4E-7 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CU254_RS10025 702e90eaeaa8f7d9c42ccdc465b541c3 264 SUPERFAMILY SSF56300 88 260 4.92E-32 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CU254_RS10025 702e90eaeaa8f7d9c42ccdc465b541c3 264 SUPERFAMILY SSF56300 2 41 4.92E-32 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CU254_RS10025 702e90eaeaa8f7d9c42ccdc465b541c3 264 Gene3D G3DSA:3.60.21.10 1 263 5.4E-26 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CU254_RS10455 029d51877f088a4af5ffe1502513e6a6 389 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 18 83 6.3E-6 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS10455 029d51877f088a4af5ffe1502513e6a6 389 Gene3D G3DSA:1.20.140.10 195 370 9.3E-18 T 28-03-2018 CU254_RS10455 029d51877f088a4af5ffe1502513e6a6 389 Gene3D G3DSA:1.10.540.10 2 109 2.4E-12 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS10455 029d51877f088a4af5ffe1502513e6a6 389 PIRSF PIRSF016578 1 389 3.3E-136 T 28-03-2018 CU254_RS10455 029d51877f088a4af5ffe1502513e6a6 389 SUPERFAMILY SSF56645 6 203 9.16E-38 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS10455 029d51877f088a4af5ffe1502513e6a6 389 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 235 367 8.5E-38 T 28-03-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain CU254_RS10455 029d51877f088a4af5ffe1502513e6a6 389 Gene3D G3DSA:2.40.110.10 110 194 5.8E-18 T 28-03-2018 CU254_RS10455 029d51877f088a4af5ffe1502513e6a6 389 SUPERFAMILY SSF47203 223 366 6.66E-15 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS31055 b326366146f024d36f5adbcfe87d2513 409 Pfam PF13740 ACT domain 6 77 1.8E-17 T 28-03-2018 CU254_RS31055 b326366146f024d36f5adbcfe87d2513 409 Gene3D G3DSA:1.10.150.210 196 242 1.4E-23 T 28-03-2018 IPR023190 Phosphoserine phosphatase, domain 2 GO:0004647|GO:0006564 KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3|Reactome: R-HSA-977347 CU254_RS31055 b326366146f024d36f5adbcfe87d2513 409 SUPERFAMILY SSF56784 183 392 2.94E-51 T 28-03-2018 IPR023214 HAD-like domain CU254_RS31055 b326366146f024d36f5adbcfe87d2513 409 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 185 355 1.1E-30 T 28-03-2018 CU254_RS31055 b326366146f024d36f5adbcfe87d2513 409 Gene3D G3DSA:3.40.50.1000 243 388 1.9E-29 T 28-03-2018 IPR023214 HAD-like domain CU254_RS31055 b326366146f024d36f5adbcfe87d2513 409 Gene3D G3DSA:3.30.70.260 1 80 8.6E-11 T 28-03-2018 CU254_RS31055 b326366146f024d36f5adbcfe87d2513 409 Gene3D G3DSA:3.30.70.260 95 181 5.5E-17 T 28-03-2018 CU254_RS31055 b326366146f024d36f5adbcfe87d2513 409 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 172 388 1.1E-76 T 28-03-2018 CU254_RS31055 b326366146f024d36f5adbcfe87d2513 409 Pfam PF12710 haloacid dehalogenase-like hydrolase 186 353 4.4E-26 T 28-03-2018 CU254_RS31055 b326366146f024d36f5adbcfe87d2513 409 SUPERFAMILY SSF55021 4 76 1.95E-6 T 28-03-2018 CU254_RS29435 3f1b008312b991a37e1eca02456fa992 95 Gene3D G3DSA:3.60.70.12 21 87 2.7E-8 T 28-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CU254_RS29435 3f1b008312b991a37e1eca02456fa992 95 SUPERFAMILY SSF56266 30 69 4.97E-5 T 28-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CU254_RS39750 05a776f1d7d37cebc09c99adaf676d85 250 Pfam PF07987 Domain of unkown function (DUF1775) 30 181 5.5E-42 T 28-03-2018 IPR012533 YcnI-like CU254_RS23710 dd784a2830d93ec5043dcc6cb35dcb1d 337 Gene3D G3DSA:3.60.130.10 19 321 3.0E-67 T 28-03-2018 CU254_RS23710 dd784a2830d93ec5043dcc6cb35dcb1d 337 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 30 317 1.4E-44 T 28-03-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 CU254_RS23710 dd784a2830d93ec5043dcc6cb35dcb1d 337 SUPERFAMILY SSF51197 32 318 3.1E-75 T 28-03-2018 CU254_RS26130 00dee92064adc9c7e34d89cc7698b0c7 386 Gene3D G3DSA:3.40.630.30 178 345 4.3E-13 T 28-03-2018 CU254_RS26130 00dee92064adc9c7e34d89cc7698b0c7 386 Pfam PF13480 Acetyltransferase (GNAT) domain 195 329 5.3E-9 T 28-03-2018 CU254_RS26130 00dee92064adc9c7e34d89cc7698b0c7 386 SUPERFAMILY SSF55729 184 330 2.12E-10 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS23950 620a894ddb0cfefd0af316915ca9ae6c 290 Gene3D G3DSA:3.40.1080.10 1 248 2.3E-55 T 28-03-2018 CU254_RS23950 620a894ddb0cfefd0af316915ca9ae6c 290 Pfam PF01144 Coenzyme A transferase 11 224 2.5E-31 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CU254_RS23950 620a894ddb0cfefd0af316915ca9ae6c 290 SMART SM00882 5 226 4.6E-26 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CU254_RS23950 620a894ddb0cfefd0af316915ca9ae6c 290 SUPERFAMILY SSF100950 4 270 1.19E-63 T 28-03-2018 CU254_RS05460 69bda3a0252108d64aa726bc93bd21e1 276 Gene3D G3DSA:3.40.50.150 1 276 1.7E-48 T 28-03-2018 CU254_RS05460 69bda3a0252108d64aa726bc93bd21e1 276 Pfam PF04672 S-adenosyl methyltransferase 13 275 6.5E-80 T 28-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CU254_RS05460 69bda3a0252108d64aa726bc93bd21e1 276 PIRSF PIRSF017393 1 276 3.5E-87 T 28-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CU254_RS05460 69bda3a0252108d64aa726bc93bd21e1 276 SUPERFAMILY SSF53335 12 261 1.32E-37 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS25400 40f22690f2b1985c67ffb8bea6ac6729 578 TIGRFAM TIGR01234 L-ribulokinase: ribulokinase 28 554 3.4E-241 T 28-03-2018 IPR005929 Ribulokinase GO:0005524|GO:0008741|GO:0019569 KEGG: 00040+2.7.1.16 CU254_RS25400 40f22690f2b1985c67ffb8bea6ac6729 578 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 312 507 6.7E-43 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CU254_RS25400 40f22690f2b1985c67ffb8bea6ac6729 578 Hamap MF_00520 Ribulokinase [araB]. 26 564 45.366 T 28-03-2018 IPR005929 Ribulokinase GO:0005524|GO:0008741|GO:0019569 KEGG: 00040+2.7.1.16 CU254_RS25400 40f22690f2b1985c67ffb8bea6ac6729 578 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 28 298 3.4E-8 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CU254_RS25400 40f22690f2b1985c67ffb8bea6ac6729 578 Gene3D G3DSA:3.30.420.40 22 294 2.5E-49 T 28-03-2018 CU254_RS25400 40f22690f2b1985c67ffb8bea6ac6729 578 PIRSF PIRSF000538 26 552 1.3E-60 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CU254_RS25400 40f22690f2b1985c67ffb8bea6ac6729 578 SUPERFAMILY SSF53067 305 553 2.41E-58 T 28-03-2018 CU254_RS25400 40f22690f2b1985c67ffb8bea6ac6729 578 Gene3D G3DSA:3.30.420.40 305 560 2.1E-59 T 28-03-2018 CU254_RS25400 40f22690f2b1985c67ffb8bea6ac6729 578 SUPERFAMILY SSF53067 29 303 9.07E-37 T 28-03-2018 CU254_RS15360 78a54fdd75cde5befe151c4904824fb5 320 SMART SM00342 227 309 4.1E-24 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS15360 78a54fdd75cde5befe151c4904824fb5 320 SUPERFAMILY SSF52317 5 192 7.57E-50 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS15360 78a54fdd75cde5befe151c4904824fb5 320 Pfam PF12833 Helix-turn-helix domain 233 311 8.8E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS15360 78a54fdd75cde5befe151c4904824fb5 320 SUPERFAMILY SSF46689 263 312 4.21E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS15360 78a54fdd75cde5befe151c4904824fb5 320 Gene3D G3DSA:1.10.10.60 228 266 2.9E-8 T 28-03-2018 CU254_RS15360 78a54fdd75cde5befe151c4904824fb5 320 Pfam PF01965 DJ-1/PfpI family 4 172 1.2E-27 T 28-03-2018 IPR002818 DJ-1/PfpI CU254_RS15360 78a54fdd75cde5befe151c4904824fb5 320 Gene3D G3DSA:1.10.10.60 267 316 1.6E-10 T 28-03-2018 CU254_RS15360 78a54fdd75cde5befe151c4904824fb5 320 Gene3D G3DSA:3.40.50.880 2 227 2.4E-65 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS31665 5a77fea9d67c001e6ba26bc689880ea6 320 SUPERFAMILY SSF88946 7 87 1.06E-21 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS31665 5a77fea9d67c001e6ba26bc689880ea6 320 TIGRFAM TIGR02960 SigX5: RNA polymerase sigma-70 factor, TIGR02960 family 7 314 4.3E-96 T 28-03-2018 IPR014305 RNA polymerase sigma-G type, actinobacteria CU254_RS31665 5a77fea9d67c001e6ba26bc689880ea6 320 SUPERFAMILY SSF54427 196 305 1.18E-16 T 28-03-2018 IPR032710 NTF2-like domain CU254_RS31665 5a77fea9d67c001e6ba26bc689880ea6 320 Gene3D G3DSA:1.10.10.10 125 201 9.1E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS31665 5a77fea9d67c001e6ba26bc689880ea6 320 Gene3D G3DSA:1.10.1740.10 5 82 6.3E-23 T 28-03-2018 CU254_RS31665 5a77fea9d67c001e6ba26bc689880ea6 320 SUPERFAMILY SSF88659 123 178 5.89E-11 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS31665 5a77fea9d67c001e6ba26bc689880ea6 320 Gene3D G3DSA:3.10.450.50 202 312 2.3E-16 T 28-03-2018 CU254_RS31665 5a77fea9d67c001e6ba26bc689880ea6 320 Pfam PF12680 SnoaL-like domain 202 298 3.6E-9 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CU254_RS31665 5a77fea9d67c001e6ba26bc689880ea6 320 Pfam PF04542 Sigma-70 region 2 15 80 3.2E-18 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS31665 5a77fea9d67c001e6ba26bc689880ea6 320 Pfam PF08281 Sigma-70, region 4 127 176 1.1E-12 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS31665 5a77fea9d67c001e6ba26bc689880ea6 320 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 17 178 8.9E-19 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS39945 51487349b2a16fd1db96aaf978f1dfcb 118 Pfam PF00581 Rhodanese-like domain 21 101 1.4E-14 T 28-03-2018 IPR001763 Rhodanese-like domain CU254_RS39945 51487349b2a16fd1db96aaf978f1dfcb 118 SMART SM00450 8 105 1.8E-21 T 28-03-2018 IPR001763 Rhodanese-like domain CU254_RS39945 51487349b2a16fd1db96aaf978f1dfcb 118 SUPERFAMILY SSF52821 7 108 1.27E-30 T 28-03-2018 IPR001763 Rhodanese-like domain CU254_RS39945 51487349b2a16fd1db96aaf978f1dfcb 118 Gene3D G3DSA:3.40.250.10 2 114 8.9E-28 T 28-03-2018 IPR001763 Rhodanese-like domain CU254_RS36960 cf7ad9f73a8a4c2b9d2610d129b4bc22 561 SMART SM00917 431 560 1.7E-35 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CU254_RS36960 cf7ad9f73a8a4c2b9d2610d129b4bc22 561 Pfam PF08502 LeuA allosteric (dimerisation) domain 431 559 1.9E-31 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CU254_RS36960 cf7ad9f73a8a4c2b9d2610d129b4bc22 561 SUPERFAMILY SSF51569 21 329 1.14E-96 T 28-03-2018 CU254_RS36960 cf7ad9f73a8a4c2b9d2610d129b4bc22 561 Pfam PF00682 HMGL-like 33 312 1.0E-76 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CU254_RS36960 cf7ad9f73a8a4c2b9d2610d129b4bc22 561 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 242 255 - T 28-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CU254_RS36960 cf7ad9f73a8a4c2b9d2610d129b4bc22 561 Hamap MF_00572 2-isopropylmalate synthase [leuA]. 3 561 55.278 T 28-03-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CU254_RS36960 cf7ad9f73a8a4c2b9d2610d129b4bc22 561 SUPERFAMILY SSF110921 456 559 1.44E-35 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CU254_RS36960 cf7ad9f73a8a4c2b9d2610d129b4bc22 561 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 39 55 - T 28-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CU254_RS36960 cf7ad9f73a8a4c2b9d2610d129b4bc22 561 SUPERFAMILY SSF89000 397 447 7.85E-14 T 28-03-2018 CU254_RS36960 cf7ad9f73a8a4c2b9d2610d129b4bc22 561 Gene3D G3DSA:3.20.20.70 9 385 4.5E-113 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS36960 cf7ad9f73a8a4c2b9d2610d129b4bc22 561 TIGRFAM TIGR00970 leuA_yeast: 2-isopropylmalate synthase 2 561 2.1E-266 T 28-03-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CU254_RS32035 a0a224f22e22ae743534eef1ebbd5961 493 Pfam PF13699 Domain of unknown function (DUF4157) 85 162 3.3E-30 T 28-03-2018 IPR025295 Domain of unknown function DUF4157 CU254_RS37210 063c0f683d51ac6d3fdb0906f9f78640 580 Gene3D G3DSA:1.10.10.10 7 61 1.6E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS37210 063c0f683d51ac6d3fdb0906f9f78640 580 SUPERFAMILY SSF53335 121 342 1.78E-43 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS37210 063c0f683d51ac6d3fdb0906f9f78640 580 Gene3D G3DSA:3.40.50.150 139 347 4.7E-31 T 28-03-2018 CU254_RS37210 063c0f683d51ac6d3fdb0906f9f78640 580 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 221 233 5.1E-12 T 28-03-2018 CU254_RS37210 063c0f683d51ac6d3fdb0906f9f78640 580 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 255 279 5.1E-12 T 28-03-2018 CU254_RS37210 063c0f683d51ac6d3fdb0906f9f78640 580 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 160 174 5.1E-12 T 28-03-2018 CU254_RS37210 063c0f683d51ac6d3fdb0906f9f78640 580 Pfam PF02384 N-6 DNA Methylase 123 309 2.4E-28 T 28-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 CU254_RS38055 9bab27bd66eb3dfe1f1958e29d96249c 94 Gene3D G3DSA:3.30.70.1060 2 86 3.4E-20 T 28-03-2018 CU254_RS38055 9bab27bd66eb3dfe1f1958e29d96249c 94 Pfam PF03795 YCII-related domain 10 83 7.1E-14 T 28-03-2018 IPR005545 YCII-related CU254_RS38055 9bab27bd66eb3dfe1f1958e29d96249c 94 SUPERFAMILY SSF54909 1 85 1.79E-21 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS36030 19d14ab2941bb695126c6146654ccb72 482 SUPERFAMILY SSF53067 2 245 1.41E-47 T 28-03-2018 CU254_RS36030 19d14ab2941bb695126c6146654ccb72 482 SUPERFAMILY SSF53067 247 470 7.05E-45 T 28-03-2018 CU254_RS36030 19d14ab2941bb695126c6146654ccb72 482 Gene3D G3DSA:3.30.420.40 240 482 1.1E-52 T 28-03-2018 CU254_RS36030 19d14ab2941bb695126c6146654ccb72 482 Gene3D G3DSA:3.30.420.40 1 239 2.4E-48 T 28-03-2018 CU254_RS36030 19d14ab2941bb695126c6146654ccb72 482 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 1 242 3.1E-40 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CU254_RS36030 19d14ab2941bb695126c6146654ccb72 482 PIRSF PIRSF000538 1 482 2.1E-86 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CU254_RS36030 19d14ab2941bb695126c6146654ccb72 482 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 254 433 8.0E-25 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CU254_RS02010 70e2d242f94aa358f60851a81a203d0a 187 Pfam PF00673 ribosomal L5P family C-terminus 91 184 1.4E-38 T 28-03-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS02010 70e2d242f94aa358f60851a81a203d0a 187 PIRSF PIRSF002161 5 187 3.2E-60 T 28-03-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS02010 70e2d242f94aa358f60851a81a203d0a 187 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 8 186 42.282 T 28-03-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS02010 70e2d242f94aa358f60851a81a203d0a 187 Pfam PF00281 Ribosomal protein L5 31 87 1.1E-25 T 28-03-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS02010 70e2d242f94aa358f60851a81a203d0a 187 SUPERFAMILY SSF55282 10 185 2.83E-71 T 28-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS02010 70e2d242f94aa358f60851a81a203d0a 187 Gene3D G3DSA:3.30.1440.10 8 186 4.9E-71 T 28-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS33950 d3c2f36aa0ff8a5a5ce8950051a4d798 482 SMART SM00862 312 377 0.0024 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS33950 d3c2f36aa0ff8a5a5ce8950051a4d798 482 Pfam PF01590 GAF domain 89 204 5.3E-8 T 28-03-2018 IPR003018 GAF domain GO:0005515 CU254_RS33950 d3c2f36aa0ff8a5a5ce8950051a4d798 482 Gene3D G3DSA:1.10.10.10 288 397 5.3E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS16605 08a68c9628f7da086b74f4633c1a6398 243 SUPERFAMILY SSF52540 3 230 1.01E-75 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS16605 08a68c9628f7da086b74f4633c1a6398 243 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS16605 08a68c9628f7da086b74f4633c1a6398 243 Pfam PF00005 ABC transporter 19 167 2.5E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS16605 08a68c9628f7da086b74f4633c1a6398 243 SMART SM00382 28 215 5.2E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS16605 08a68c9628f7da086b74f4633c1a6398 243 PIRSF PIRSF039085 1 243 5.9E-104 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CU254_RS16605 08a68c9628f7da086b74f4633c1a6398 243 Gene3D G3DSA:3.40.50.300 1 241 4.5E-74 T 28-03-2018 CU254_RS36365 b73f7b1a3561aafe2d56e425c95186d2 338 TIGRFAM TIGR03624 TIGR03624: putative hydrolase 2 336 9.6E-100 T 28-03-2018 IPR018766 Zinicin-like metallopeptidase type 2 CU254_RS36365 b73f7b1a3561aafe2d56e425c95186d2 338 Pfam PF10103 Zincin-like metallopeptidase 2 333 6.3E-110 T 28-03-2018 IPR018766 Zinicin-like metallopeptidase type 2 CU254_RS36365 b73f7b1a3561aafe2d56e425c95186d2 338 SUPERFAMILY SSF55486 1 336 2.56E-100 T 28-03-2018 CU254_RS36365 b73f7b1a3561aafe2d56e425c95186d2 338 TIGRFAM TIGR03883 DUF2342_F420: uncharacterized protein, coenzyme F420 biosynthesis associated 2 337 7.4E-120 T 28-03-2018 IPR022454 Conserved hypothetical protein CHP03883, F420 biosynthesis associated CU254_RS05380 825fb080d27b19fb1612b83c88a93e32 211 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 204 21.965 T 28-03-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 CU254_RS05380 825fb080d27b19fb1612b83c88a93e32 211 Pfam PF02525 Flavodoxin-like fold 3 167 7.3E-26 T 28-03-2018 IPR003680 Flavodoxin-like fold CU254_RS05380 825fb080d27b19fb1612b83c88a93e32 211 Gene3D G3DSA:3.40.50.360 3 210 6.9E-29 T 28-03-2018 IPR029039 Flavoprotein-like domain CU254_RS05380 825fb080d27b19fb1612b83c88a93e32 211 SUPERFAMILY SSF52218 1 204 4.03E-31 T 28-03-2018 IPR029039 Flavoprotein-like domain CU254_RS28950 578a2442b99dccdd2b039311d7481c5b 623 SUPERFAMILY SSF53067 184 375 2.32E-64 T 28-03-2018 CU254_RS28950 578a2442b99dccdd2b039311d7481c5b 623 Gene3D G3DSA:3.90.640.10 233 306 4.2E-25 T 28-03-2018 CU254_RS28950 578a2442b99dccdd2b039311d7481c5b 623 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 189 202 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CU254_RS28950 578a2442b99dccdd2b039311d7481c5b 623 Gene3D G3DSA:3.30.420.40 190 232 3.4E-15 T 28-03-2018 CU254_RS28950 578a2442b99dccdd2b039311d7481c5b 623 SUPERFAMILY SSF100920 378 534 6.28E-58 T 28-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 CU254_RS28950 578a2442b99dccdd2b039311d7481c5b 623 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 596 8.6E-284 T 28-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 CU254_RS28950 578a2442b99dccdd2b039311d7481c5b 623 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CU254_RS28950 578a2442b99dccdd2b039311d7481c5b 623 Gene3D G3DSA:3.30.420.40 1 189 7.3E-76 T 28-03-2018 CU254_RS28950 578a2442b99dccdd2b039311d7481c5b 623 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 623 35.703 T 28-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 CU254_RS28950 578a2442b99dccdd2b039311d7481c5b 623 PRINTS PR00301 70kDa heat shock protein signature 382 401 5.6E-79 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CU254_RS28950 578a2442b99dccdd2b039311d7481c5b 623 PRINTS PR00301 70kDa heat shock protein signature 359 379 5.6E-79 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CU254_RS28950 578a2442b99dccdd2b039311d7481c5b 623 PRINTS PR00301 70kDa heat shock protein signature 54 62 5.6E-79 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CU254_RS28950 578a2442b99dccdd2b039311d7481c5b 623 PRINTS PR00301 70kDa heat shock protein signature 136 156 5.6E-79 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CU254_RS28950 578a2442b99dccdd2b039311d7481c5b 623 PRINTS PR00301 70kDa heat shock protein signature 195 205 5.6E-79 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CU254_RS28950 578a2442b99dccdd2b039311d7481c5b 623 PRINTS PR00301 70kDa heat shock protein signature 463 479 5.6E-79 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CU254_RS28950 578a2442b99dccdd2b039311d7481c5b 623 PRINTS PR00301 70kDa heat shock protein signature 3 16 5.6E-79 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CU254_RS28950 578a2442b99dccdd2b039311d7481c5b 623 PRINTS PR00301 70kDa heat shock protein signature 327 343 5.6E-79 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CU254_RS28950 578a2442b99dccdd2b039311d7481c5b 623 PRINTS PR00301 70kDa heat shock protein signature 31 43 5.6E-79 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CU254_RS28950 578a2442b99dccdd2b039311d7481c5b 623 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 330 344 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CU254_RS28950 578a2442b99dccdd2b039311d7481c5b 623 Gene3D G3DSA:3.40.50.970 307 389 0.0051 T 28-03-2018 CU254_RS28950 578a2442b99dccdd2b039311d7481c5b 623 Gene3D G3DSA:1.20.1270.10 510 601 1.8E-15 T 28-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain CU254_RS28950 578a2442b99dccdd2b039311d7481c5b 623 Pfam PF00012 Hsp70 protein 4 593 3.9E-244 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CU254_RS28950 578a2442b99dccdd2b039311d7481c5b 623 Gene3D G3DSA:2.60.34.10 390 509 1.1E-59 T 28-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 CU254_RS28950 578a2442b99dccdd2b039311d7481c5b 623 SUPERFAMILY SSF53067 4 182 2.59E-62 T 28-03-2018 CU254_RS01675 3de3c06ced9260edf911493ce96b2ab2 873 Pfam PF01590 GAF domain 360 423 6.5E-5 T 28-03-2018 IPR003018 GAF domain GO:0005515 CU254_RS01675 3de3c06ced9260edf911493ce96b2ab2 873 Pfam PF00563 EAL domain 610 843 5.9E-69 T 28-03-2018 IPR001633 EAL domain CU254_RS01675 3de3c06ced9260edf911493ce96b2ab2 873 SMART SM00065 294 434 4.8E-7 T 28-03-2018 IPR003018 GAF domain GO:0005515 CU254_RS01675 3de3c06ced9260edf911493ce96b2ab2 873 SUPERFAMILY SSF55073 442 585 1.02E-22 T 28-03-2018 IPR029787 Nucleotide cyclase CU254_RS01675 3de3c06ced9260edf911493ce96b2ab2 873 SMART SM00052 603 848 2.3E-102 T 28-03-2018 IPR001633 EAL domain CU254_RS01675 3de3c06ced9260edf911493ce96b2ab2 873 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 434 584 9.5E-13 T 28-03-2018 IPR000160 GGDEF domain CU254_RS01675 3de3c06ced9260edf911493ce96b2ab2 873 Gene3D G3DSA:3.30.450.40 248 434 3.0E-21 T 28-03-2018 IPR029016 GAF domain-like CU254_RS01675 3de3c06ced9260edf911493ce96b2ab2 873 SMART SM00267 426 593 2.1E-16 T 28-03-2018 IPR000160 GGDEF domain CU254_RS01675 3de3c06ced9260edf911493ce96b2ab2 873 Gene3D G3DSA:3.20.20.450 602 861 7.4E-93 T 28-03-2018 IPR001633 EAL domain CU254_RS01675 3de3c06ced9260edf911493ce96b2ab2 873 Gene3D G3DSA:3.30.70.270 435 601 5.2E-32 T 28-03-2018 CU254_RS01675 3de3c06ced9260edf911493ce96b2ab2 873 SUPERFAMILY SSF141868 610 856 4.58E-82 T 28-03-2018 IPR001633 EAL domain CU254_RS01675 3de3c06ced9260edf911493ce96b2ab2 873 Pfam PF00990 Diguanylate cyclase, GGDEF domain 437 583 7.7E-17 T 28-03-2018 IPR000160 GGDEF domain CU254_RS01675 3de3c06ced9260edf911493ce96b2ab2 873 SUPERFAMILY SSF55781 299 435 1.05E-10 T 28-03-2018 IPR029016 GAF domain-like CU254_RS29160 2db14288b704ca1db1a6be37fc49804f 195 Gene3D G3DSA:3.40.50.2300 1 116 2.9E-31 T 28-03-2018 CU254_RS29160 2db14288b704ca1db1a6be37fc49804f 195 Gene3D G3DSA:1.10.10.10 117 195 2.8E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS29160 2db14288b704ca1db1a6be37fc49804f 195 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 134 148 1.2E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS29160 2db14288b704ca1db1a6be37fc49804f 195 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 148 164 1.2E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS29160 2db14288b704ca1db1a6be37fc49804f 195 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 176 1.2E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS29160 2db14288b704ca1db1a6be37fc49804f 195 SMART SM00421 131 188 6.2E-26 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS29160 2db14288b704ca1db1a6be37fc49804f 195 Pfam PF00196 Bacterial regulatory proteins, luxR family 133 188 4.5E-20 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS29160 2db14288b704ca1db1a6be37fc49804f 195 SUPERFAMILY SSF52172 2 123 1.57E-28 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS29160 2db14288b704ca1db1a6be37fc49804f 195 SUPERFAMILY SSF46894 122 194 1.09E-22 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS29160 2db14288b704ca1db1a6be37fc49804f 195 SMART SM00448 1 105 5.2E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS29160 2db14288b704ca1db1a6be37fc49804f 195 Pfam PF00072 Response regulator receiver domain 2 106 1.3E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS29160 2db14288b704ca1db1a6be37fc49804f 195 ProSitePatterns PS00622 LuxR-type HTH domain signature. 148 175 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS13040 ad09d3f95a0b4622cbcaa180440cf765 407 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 247 397 7.4E-34 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS13040 ad09d3f95a0b4622cbcaa180440cf765 407 SUPERFAMILY SSF56645 1 260 1.03E-63 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS13040 ad09d3f95a0b4622cbcaa180440cf765 407 SUPERFAMILY SSF47203 245 402 6.6E-41 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS13040 ad09d3f95a0b4622cbcaa180440cf765 407 Gene3D G3DSA:1.10.540.10 1 132 1.0E-29 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS13040 ad09d3f95a0b4622cbcaa180440cf765 407 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 129 1.9E-11 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS13040 ad09d3f95a0b4622cbcaa180440cf765 407 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 133 235 3.5E-20 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CU254_RS13040 ad09d3f95a0b4622cbcaa180440cf765 407 Gene3D G3DSA:2.40.110.10 133 235 6.0E-34 T 28-03-2018 CU254_RS13040 ad09d3f95a0b4622cbcaa180440cf765 407 Gene3D G3DSA:1.20.140.10 236 407 4.9E-44 T 28-03-2018 CU254_RS30475 1a8ba307e5fdabad695ecc2c8949ffd2 161 SUPERFAMILY SSF46785 14 61 4.26E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS30475 1a8ba307e5fdabad695ecc2c8949ffd2 161 SMART SM00344 14 118 8.3E-30 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CU254_RS30475 1a8ba307e5fdabad695ecc2c8949ffd2 161 Pfam PF01037 Lrp/AsnC ligand binding domain 79 148 5.4E-13 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CU254_RS30475 1a8ba307e5fdabad695ecc2c8949ffd2 161 Pfam PF13404 AsnC-type helix-turn-helix domain 15 54 1.3E-15 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS30475 1a8ba307e5fdabad695ecc2c8949ffd2 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 14 30 2.1E-12 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS30475 1a8ba307e5fdabad695ecc2c8949ffd2 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 41 2.1E-12 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS30475 1a8ba307e5fdabad695ecc2c8949ffd2 161 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 41 60 2.1E-12 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS30475 1a8ba307e5fdabad695ecc2c8949ffd2 161 Gene3D G3DSA:3.30.70.920 66 157 3.3E-15 T 28-03-2018 CU254_RS30475 1a8ba307e5fdabad695ecc2c8949ffd2 161 SUPERFAMILY SSF54909 76 154 2.15E-13 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS30475 1a8ba307e5fdabad695ecc2c8949ffd2 161 Gene3D G3DSA:1.10.10.10 13 65 5.9E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS03355 5633cff5edfd4ba18cb2d36e8ade62f9 268 Pfam PF14021 Tuberculosis necrotizing toxin 178 263 3.5E-28 T 28-03-2018 IPR025331 Tuberculosis necrotizing toxin CU254_RS35770 702beb313b2d8b40e5d9a6f3bf5eb3b4 425 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 17 170 1.2E-15 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS35770 702beb313b2d8b40e5d9a6f3bf5eb3b4 425 SUPERFAMILY SSF88946 4 73 6.28E-13 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS35770 702beb313b2d8b40e5d9a6f3bf5eb3b4 425 Gene3D G3DSA:1.10.10.10 98 172 3.1E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS35770 702beb313b2d8b40e5d9a6f3bf5eb3b4 425 Gene3D G3DSA:1.10.1740.10 2 80 1.6E-14 T 28-03-2018 CU254_RS35770 702beb313b2d8b40e5d9a6f3bf5eb3b4 425 SUPERFAMILY SSF88659 107 170 1.4E-11 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS35770 702beb313b2d8b40e5d9a6f3bf5eb3b4 425 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 32 63 - T 28-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS35770 702beb313b2d8b40e5d9a6f3bf5eb3b4 425 Pfam PF08281 Sigma-70, region 4 119 168 1.0E-10 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS35770 702beb313b2d8b40e5d9a6f3bf5eb3b4 425 Pfam PF04542 Sigma-70 region 2 18 75 4.9E-11 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS13865 f526e838796002e8ecde1a0664e4fc53 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 2.1E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS13865 f526e838796002e8ecde1a0664e4fc53 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 2.1E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS13865 f526e838796002e8ecde1a0664e4fc53 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 64 9.6E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS13865 f526e838796002e8ecde1a0664e4fc53 211 Gene3D G3DSA:1.10.10.60 1 53 4.7E-18 T 28-03-2018 CU254_RS13865 f526e838796002e8ecde1a0664e4fc53 211 SUPERFAMILY SSF46689 8 88 2.6E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS13865 f526e838796002e8ecde1a0664e4fc53 211 Gene3D G3DSA:1.10.10.60 54 177 9.2E-9 T 28-03-2018 CU254_RS01525 0652fda19bab7b9b34e7ad20e9fb3e40 289 SUPERFAMILY SSF53448 6 215 2.53E-19 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS01525 0652fda19bab7b9b34e7ad20e9fb3e40 289 Gene3D G3DSA:3.90.550.10 3 221 3.8E-15 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS01525 0652fda19bab7b9b34e7ad20e9fb3e40 289 Pfam PF00535 Glycosyl transferase family 2 7 109 9.7E-12 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CU254_RS29315 4fdc08bbb759791afb447d8ec082a539 173 SUPERFAMILY SSF53271 12 157 5.82E-29 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CU254_RS29315 4fdc08bbb759791afb447d8ec082a539 173 Pfam PF00156 Phosphoribosyl transferase domain 25 155 1.2E-12 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CU254_RS29315 4fdc08bbb759791afb447d8ec082a539 173 Gene3D G3DSA:3.40.50.2020 4 166 2.8E-24 T 28-03-2018 CU254_RS08365 0caed581fa20c2362a97e8169f1bf3fb 444 Gene3D G3DSA:2.60.40.1180 354 443 9.3E-26 T 28-03-2018 CU254_RS08365 0caed581fa20c2362a97e8169f1bf3fb 444 SUPERFAMILY SSF51011 356 441 5.86E-18 T 28-03-2018 CU254_RS08365 0caed581fa20c2362a97e8169f1bf3fb 444 Pfam PF16499 Alpha galactosidase A 43 129 4.2E-15 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CU254_RS08365 0caed581fa20c2362a97e8169f1bf3fb 444 Pfam PF16499 Alpha galactosidase A 172 354 9.9E-22 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CU254_RS08365 0caed581fa20c2362a97e8169f1bf3fb 444 PRINTS PR00740 Glycosyl hydrolase family 27 signature 213 231 3.2E-19 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CU254_RS08365 0caed581fa20c2362a97e8169f1bf3fb 444 PRINTS PR00740 Glycosyl hydrolase family 27 signature 113 134 3.2E-19 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CU254_RS08365 0caed581fa20c2362a97e8169f1bf3fb 444 PRINTS PR00740 Glycosyl hydrolase family 27 signature 287 306 3.2E-19 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CU254_RS08365 0caed581fa20c2362a97e8169f1bf3fb 444 PRINTS PR00740 Glycosyl hydrolase family 27 signature 38 57 3.2E-19 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CU254_RS08365 0caed581fa20c2362a97e8169f1bf3fb 444 PRINTS PR00740 Glycosyl hydrolase family 27 signature 73 88 3.2E-19 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CU254_RS08365 0caed581fa20c2362a97e8169f1bf3fb 444 Gene3D G3DSA:3.20.20.70 35 353 7.1E-81 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS08365 0caed581fa20c2362a97e8169f1bf3fb 444 SUPERFAMILY SSF51445 166 354 1.54E-69 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS08365 0caed581fa20c2362a97e8169f1bf3fb 444 SUPERFAMILY SSF51445 39 131 1.54E-69 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS21270 9c9d77afbe70879ae9c86d5219920dba 228 Gene3D G3DSA:2.30.110.10 7 212 4.3E-39 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS21270 9c9d77afbe70879ae9c86d5219920dba 228 SMART SM00903 15 177 0.0026 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CU254_RS21270 9c9d77afbe70879ae9c86d5219920dba 228 Pfam PF01613 Flavin reductase like domain 18 171 4.3E-12 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CU254_RS21270 9c9d77afbe70879ae9c86d5219920dba 228 SUPERFAMILY SSF50475 11 217 5.5E-34 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS28725 e7b34ddd696eeb7aca3ad7f32a4185b3 217 Pfam PF00218 Indole-3-glycerol phosphate synthase 56 169 5.1E-16 T 28-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 CU254_RS28725 e7b34ddd696eeb7aca3ad7f32a4185b3 217 SUPERFAMILY SSF51366 36 195 1.77E-20 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CU254_RS28725 e7b34ddd696eeb7aca3ad7f32a4185b3 217 Gene3D G3DSA:3.20.20.70 7 208 8.1E-16 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS32040 6e38cc4f6cfe745482cf5edd23138188 937 Gene3D G3DSA:3.40.50.2300 520 717 9.6E-11 T 28-03-2018 CU254_RS32040 6e38cc4f6cfe745482cf5edd23138188 937 SUPERFAMILY SSF53822 575 914 2.03E-12 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CU254_RS18625 8632bf043d3a24ee9a53f67cb57a05b9 276 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 67 273 3.3E-59 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CU254_RS18625 8632bf043d3a24ee9a53f67cb57a05b9 276 Gene3D G3DSA:3.90.850.10 34 276 6.7E-69 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CU254_RS18625 8632bf043d3a24ee9a53f67cb57a05b9 276 SUPERFAMILY SSF56529 56 274 2.35E-69 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CU254_RS32950 fb6d82ee08f9193bccca9e9e5ed319a6 156 SMART SM00344 2 108 2.3E-20 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CU254_RS32950 fb6d82ee08f9193bccca9e9e5ed319a6 156 SUPERFAMILY SSF54909 62 146 2.28E-18 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS32950 fb6d82ee08f9193bccca9e9e5ed319a6 156 Gene3D G3DSA:3.30.70.920 55 148 1.8E-19 T 28-03-2018 CU254_RS32950 fb6d82ee08f9193bccca9e9e5ed319a6 156 Pfam PF01037 Lrp/AsnC ligand binding domain 77 138 1.1E-15 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CU254_RS32950 fb6d82ee08f9193bccca9e9e5ed319a6 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 2 18 2.9E-9 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS32950 fb6d82ee08f9193bccca9e9e5ed319a6 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 29 48 2.9E-9 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS32950 fb6d82ee08f9193bccca9e9e5ed319a6 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 18 29 2.9E-9 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS32950 fb6d82ee08f9193bccca9e9e5ed319a6 156 Gene3D G3DSA:1.10.10.10 2 51 1.9E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS32950 fb6d82ee08f9193bccca9e9e5ed319a6 156 SUPERFAMILY SSF46785 2 73 1.96E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS32950 fb6d82ee08f9193bccca9e9e5ed319a6 156 Pfam PF13404 AsnC-type helix-turn-helix domain 2 42 1.0E-7 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS29100 b49cbe84ea72525d47bd57afc4cfff5d 356 Pfam PF05343 M42 glutamyl aminopeptidase 64 345 3.9E-70 T 28-03-2018 IPR008007 Peptidase M42 CU254_RS29100 b49cbe84ea72525d47bd57afc4cfff5d 356 Gene3D G3DSA:3.40.630.10 215 352 1.3E-22 T 28-03-2018 CU254_RS29100 b49cbe84ea72525d47bd57afc4cfff5d 356 Gene3D G3DSA:3.40.630.10 170 214 3.6E-5 T 28-03-2018 CU254_RS29100 b49cbe84ea72525d47bd57afc4cfff5d 356 Gene3D G3DSA:2.40.30.40 80 168 1.2E-22 T 28-03-2018 IPR023367 Peptidase M42, domain 2 CU254_RS29100 b49cbe84ea72525d47bd57afc4cfff5d 356 SUPERFAMILY SSF101821 81 185 1.83E-22 T 28-03-2018 CU254_RS29100 b49cbe84ea72525d47bd57afc4cfff5d 356 PIRSF PIRSF001123 15 355 1.2E-71 T 28-03-2018 IPR008007 Peptidase M42 CU254_RS29100 b49cbe84ea72525d47bd57afc4cfff5d 356 SUPERFAMILY SSF53187 19 93 1.09E-45 T 28-03-2018 CU254_RS29100 b49cbe84ea72525d47bd57afc4cfff5d 356 SUPERFAMILY SSF53187 180 350 1.09E-45 T 28-03-2018 CU254_RS28440 0f1fa9ea1b0899057f79b2d184d8eab3 213 SMART SM00448 2 115 4.1E-35 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS28440 0f1fa9ea1b0899057f79b2d184d8eab3 213 ProSitePatterns PS00622 LuxR-type HTH domain signature. 167 194 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS28440 0f1fa9ea1b0899057f79b2d184d8eab3 213 SMART SM00421 150 207 8.7E-22 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS28440 0f1fa9ea1b0899057f79b2d184d8eab3 213 Gene3D G3DSA:1.10.10.10 134 212 6.1E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS28440 0f1fa9ea1b0899057f79b2d184d8eab3 213 Gene3D G3DSA:3.40.50.2300 1 133 5.2E-40 T 28-03-2018 CU254_RS28440 0f1fa9ea1b0899057f79b2d184d8eab3 213 SUPERFAMILY SSF52172 3 134 7.54E-35 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS28440 0f1fa9ea1b0899057f79b2d184d8eab3 213 Pfam PF00072 Response regulator receiver domain 4 115 6.7E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS28440 0f1fa9ea1b0899057f79b2d184d8eab3 213 SUPERFAMILY SSF46894 143 212 2.86E-20 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS28440 0f1fa9ea1b0899057f79b2d184d8eab3 213 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 206 2.3E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS28440 0f1fa9ea1b0899057f79b2d184d8eab3 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 8.8E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS28440 0f1fa9ea1b0899057f79b2d184d8eab3 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 8.8E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS28440 0f1fa9ea1b0899057f79b2d184d8eab3 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 8.8E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS21335 061c31685b5869c6cb165e2945d01765 252 SUPERFAMILY SSF53335 8 150 6.43E-25 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS21335 061c31685b5869c6cb165e2945d01765 252 Pfam PF13649 Methyltransferase domain 42 128 5.4E-11 T 28-03-2018 CU254_RS21335 061c31685b5869c6cb165e2945d01765 252 Gene3D G3DSA:3.40.50.150 5 236 2.0E-22 T 28-03-2018 CU254_RS02090 ae5b98ebd00916b30ed5f1d71ae1b4c4 134 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 15 131 2.0E-58 T 28-03-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS02090 ae5b98ebd00916b30ed5f1d71ae1b4c4 134 ProSitePatterns PS00054 Ribosomal protein S11 signature. 102 124 - T 28-03-2018 IPR018102 Ribosomal S11, conserved site CU254_RS02090 ae5b98ebd00916b30ed5f1d71ae1b4c4 134 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 4 134 33.998 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CU254_RS02090 ae5b98ebd00916b30ed5f1d71ae1b4c4 134 Gene3D G3DSA:3.30.420.80 8 134 1.3E-46 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CU254_RS02090 ae5b98ebd00916b30ed5f1d71ae1b4c4 134 Pfam PF00411 Ribosomal protein S11 24 133 3.8E-49 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CU254_RS02090 ae5b98ebd00916b30ed5f1d71ae1b4c4 134 SUPERFAMILY SSF53137 19 134 1.12E-49 T 28-03-2018 CU254_RS02090 ae5b98ebd00916b30ed5f1d71ae1b4c4 134 PIRSF PIRSF002131 4 134 8.5E-54 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CU254_RS15395 d12f103d95704510f60a7dfb63f306e0 382 Gene3D G3DSA:3.30.2010.10 147 276 4.2E-5 T 28-03-2018 CU254_RS37915 1cc85bcb0e80e0e461c3341bf008e812 511 PIRSF PIRSF006060 7 504 6.4E-67 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CU254_RS37915 1cc85bcb0e80e0e461c3341bf008e812 511 ProSitePatterns PS00218 Amino acid permeases signature. 61 92 - T 28-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CU254_RS37915 1cc85bcb0e80e0e461c3341bf008e812 511 Pfam PF13520 Amino acid permease 33 472 2.1E-67 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CU254_RS23275 ee9d162a12c55570f6d84e067c2ec389 152 Pfam PF13412 Winged helix-turn-helix DNA-binding 7 53 2.5E-19 T 28-03-2018 CU254_RS23275 ee9d162a12c55570f6d84e067c2ec389 152 Pfam PF01037 Lrp/AsnC ligand binding domain 79 146 2.8E-15 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CU254_RS23275 ee9d162a12c55570f6d84e067c2ec389 152 Gene3D G3DSA:1.10.10.10 8 59 3.9E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS23275 ee9d162a12c55570f6d84e067c2ec389 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 34 53 1.7E-18 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS23275 ee9d162a12c55570f6d84e067c2ec389 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 7 23 1.7E-18 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS23275 ee9d162a12c55570f6d84e067c2ec389 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 23 34 1.7E-18 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS23275 ee9d162a12c55570f6d84e067c2ec389 152 SMART SM00344 7 116 1.4E-33 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CU254_RS23275 ee9d162a12c55570f6d84e067c2ec389 152 SUPERFAMILY SSF46785 6 66 9.11E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS23275 ee9d162a12c55570f6d84e067c2ec389 152 ProSitePatterns PS00519 AsnC-type HTH domain signature. 25 51 - T 28-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site CU254_RS23275 ee9d162a12c55570f6d84e067c2ec389 152 Gene3D G3DSA:3.30.70.920 60 152 4.0E-19 T 28-03-2018 CU254_RS23275 ee9d162a12c55570f6d84e067c2ec389 152 SUPERFAMILY SSF54909 77 150 2.15E-13 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS04350 a70a94b0b7c1aabe0cc93794d99da9b6 475 Gene3D G3DSA:3.40.309.10 262 454 1.3E-59 T 28-03-2018 CU254_RS04350 a70a94b0b7c1aabe0cc93794d99da9b6 475 Pfam PF00171 Aldehyde dehydrogenase family 16 466 7.9E-128 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CU254_RS04350 a70a94b0b7c1aabe0cc93794d99da9b6 475 Gene3D G3DSA:3.40.605.10 1 261 9.2E-71 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CU254_RS04350 a70a94b0b7c1aabe0cc93794d99da9b6 475 SUPERFAMILY SSF53720 2 469 2.36E-131 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CU254_RS30020 662f210daa38281f434af38549b95cd2 208 ProSitePatterns PS01081 TetR-type HTH domain signature. 30 60 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CU254_RS30020 662f210daa38281f434af38549b95cd2 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 64 1.3E-17 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS30020 662f210daa38281f434af38549b95cd2 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 8.6E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS30020 662f210daa38281f434af38549b95cd2 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 8.6E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS30020 662f210daa38281f434af38549b95cd2 208 SUPERFAMILY SSF48498 84 196 2.97E-14 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS30020 662f210daa38281f434af38549b95cd2 208 SUPERFAMILY SSF46689 7 77 1.74E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS30020 662f210daa38281f434af38549b95cd2 208 Gene3D G3DSA:1.10.357.10 5 207 2.8E-34 T 28-03-2018 CU254_RS36500 b59245f2463e23faca5a7e39878c6f1a 761 TIGRFAM TIGR01104 V_PPase: V-type H(+)-translocating pyrophosphatase 23 715 5.6E-208 T 28-03-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CU254_RS36500 b59245f2463e23faca5a7e39878c6f1a 761 Pfam PF03030 Inorganic H+ pyrophosphatase 29 709 8.1E-241 T 28-03-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CU254_RS36500 b59245f2463e23faca5a7e39878c6f1a 761 Hamap MF_01129 Putative K(+)-stimulated pyrophosphate-energized sodium pump [hppA]. 18 714 24.328 T 28-03-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CU254_RS36500 b59245f2463e23faca5a7e39878c6f1a 761 PIRSF PIRSF001265 15 721 4.7E-249 T 28-03-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CU254_RS18580 d29d08e196ee74605004db0195205ef3 226 Gene3D G3DSA:3.40.50.2300 1 119 4.8E-38 T 28-03-2018 CU254_RS18580 d29d08e196ee74605004db0195205ef3 226 SUPERFAMILY SSF52172 3 176 2.64E-42 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS18580 d29d08e196ee74605004db0195205ef3 226 SMART SM00448 3 113 9.8E-41 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS18580 d29d08e196ee74605004db0195205ef3 226 SMART SM00862 146 222 3.8E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS18580 d29d08e196ee74605004db0195205ef3 226 Pfam PF00072 Response regulator receiver domain 5 113 4.1E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS18580 d29d08e196ee74605004db0195205ef3 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 221 5.9E-26 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS18580 d29d08e196ee74605004db0195205ef3 226 Gene3D G3DSA:1.10.10.10 120 226 9.8E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS39460 f7fa6a0c99b861e82964e5864f0f37e2 298 SUPERFAMILY SSF51735 114 295 4.79E-22 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS39460 f7fa6a0c99b861e82964e5864f0f37e2 298 Gene3D G3DSA:3.90.180.10 174 296 9.5E-11 T 28-03-2018 CU254_RS39460 f7fa6a0c99b861e82964e5864f0f37e2 298 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 87 8.5E-6 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CU254_RS39460 f7fa6a0c99b861e82964e5864f0f37e2 298 SMART SM00829 10 296 6.0E-10 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CU254_RS39460 f7fa6a0c99b861e82964e5864f0f37e2 298 Gene3D G3DSA:3.90.180.10 1 173 6.7E-38 T 28-03-2018 CU254_RS39460 f7fa6a0c99b861e82964e5864f0f37e2 298 Pfam PF13602 Zinc-binding dehydrogenase 195 295 1.1E-14 T 28-03-2018 CU254_RS39460 f7fa6a0c99b861e82964e5864f0f37e2 298 SUPERFAMILY SSF50129 2 119 8.49E-23 T 28-03-2018 IPR011032 GroES-like CU254_RS39460 f7fa6a0c99b861e82964e5864f0f37e2 298 SUPERFAMILY SSF50129 152 159 8.49E-23 T 28-03-2018 IPR011032 GroES-like CU254_RS13415 2f8026395d8983dd99577210d18784e3 399 TIGRFAM TIGR02091 glgC: glucose-1-phosphate adenylyltransferase 1 372 1.2E-134 T 28-03-2018 IPR011831 Glucose-1-phosphate adenylyltransferase GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 CU254_RS13415 2f8026395d8983dd99577210d18784e3 399 ProSitePatterns PS00808 ADP-glucose pyrophosphorylase signature 1. 7 26 - T 28-03-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 CU254_RS13415 2f8026395d8983dd99577210d18784e3 399 SUPERFAMILY SSF53448 2 274 1.78E-67 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS13415 2f8026395d8983dd99577210d18784e3 399 SUPERFAMILY SSF53448 336 352 1.78E-67 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS13415 2f8026395d8983dd99577210d18784e3 399 Gene3D G3DSA:3.90.550.10 1 280 2.1E-53 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS13415 2f8026395d8983dd99577210d18784e3 399 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 92 100 - T 28-03-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 CU254_RS13415 2f8026395d8983dd99577210d18784e3 399 Hamap MF_00624 Glucose-1-phosphate adenylyltransferase [glgC]. 1 398 44.499 T 28-03-2018 IPR023049 Glucose-1-phosphate adenylyltransferase GlgC, bacterial GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 CU254_RS13415 2f8026395d8983dd99577210d18784e3 399 SUPERFAMILY SSF51161 306 390 4.99E-17 T 28-03-2018 IPR011004 Trimeric LpxA-like CU254_RS13415 2f8026395d8983dd99577210d18784e3 399 Pfam PF00483 Nucleotidyl transferase 3 270 1.2E-67 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CU254_RS13415 2f8026395d8983dd99577210d18784e3 399 ProSitePatterns PS00810 ADP-glucose pyrophosphorylase signature 3. 190 200 - T 28-03-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 CU254_RS13415 2f8026395d8983dd99577210d18784e3 399 Gene3D G3DSA:2.160.10.10 289 390 6.1E-11 T 28-03-2018 CU254_RS07120 963f887be10623b4d03e7622ace66cef 77 Pfam PF01037 Lrp/AsnC ligand binding domain 6 74 1.4E-11 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CU254_RS07120 963f887be10623b4d03e7622ace66cef 77 Gene3D G3DSA:3.30.70.920 1 77 2.7E-15 T 28-03-2018 CU254_RS07120 963f887be10623b4d03e7622ace66cef 77 SUPERFAMILY SSF54909 2 75 9.79E-14 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS22160 db2cb3c56c827fbf3ac2045fc10b6f70 487 Pfam PF13450 NAD(P)-binding Rossmann-like domain 9 56 1.0E-7 T 28-03-2018 CU254_RS22160 db2cb3c56c827fbf3ac2045fc10b6f70 487 Gene3D G3DSA:3.50.50.60 162 441 8.4E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS22160 db2cb3c56c827fbf3ac2045fc10b6f70 487 Pfam PF00743 Flavin-binding monooxygenase-like 79 218 3.3E-16 T 28-03-2018 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 CU254_RS22160 db2cb3c56c827fbf3ac2045fc10b6f70 487 SUPERFAMILY SSF51905 5 229 3.52E-51 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS22160 db2cb3c56c827fbf3ac2045fc10b6f70 487 SUPERFAMILY SSF51905 298 405 3.52E-51 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS22160 db2cb3c56c827fbf3ac2045fc10b6f70 487 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 177 202 3.3E-6 T 28-03-2018 CU254_RS22160 db2cb3c56c827fbf3ac2045fc10b6f70 487 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 3.3E-6 T 28-03-2018 CU254_RS22160 db2cb3c56c827fbf3ac2045fc10b6f70 487 Gene3D G3DSA:3.50.50.60 4 161 1.5E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS26560 26a13f4bdab0fe5c203768b7fd2ebe09 272 SUPERFAMILY SSF63380 13 132 5.3E-10 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CU254_RS26560 26a13f4bdab0fe5c203768b7fd2ebe09 272 Gene3D G3DSA:3.40.50.80 133 272 5.9E-45 T 28-03-2018 CU254_RS26560 26a13f4bdab0fe5c203768b7fd2ebe09 272 Pfam PF08021 Siderophore-interacting FAD-binding domain 16 131 2.1E-35 T 28-03-2018 IPR013113 FAD-binding 9, siderophore-interacting CU254_RS26560 26a13f4bdab0fe5c203768b7fd2ebe09 272 Pfam PF04954 Siderophore-interacting protein 138 252 1.9E-36 T 28-03-2018 IPR007037 Siderophore-interacting protein CU254_RS26560 26a13f4bdab0fe5c203768b7fd2ebe09 272 Gene3D G3DSA:2.40.30.10 5 131 4.3E-32 T 28-03-2018 CU254_RS14035 acbfa8d839ddfd4d5d47e236def86964 261 PIRSF PIRSF039085 1 254 9.2E-106 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CU254_RS14035 acbfa8d839ddfd4d5d47e236def86964 261 Gene3D G3DSA:3.40.50.300 1 261 1.1E-76 T 28-03-2018 CU254_RS14035 acbfa8d839ddfd4d5d47e236def86964 261 Pfam PF00005 ABC transporter 20 178 1.8E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS14035 acbfa8d839ddfd4d5d47e236def86964 261 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS14035 acbfa8d839ddfd4d5d47e236def86964 261 SMART SM00382 29 226 2.9E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS14035 acbfa8d839ddfd4d5d47e236def86964 261 SUPERFAMILY SSF52540 6 248 3.71E-74 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS14975 6ea2695a62adb7652c2eb9cbda7d2f20 273 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 263 4.9E-13 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS14975 6ea2695a62adb7652c2eb9cbda7d2f20 273 SUPERFAMILY SSF161098 16 266 2.35E-54 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS14975 6ea2695a62adb7652c2eb9cbda7d2f20 273 Gene3D G3DSA:1.10.3720.10 18 271 2.6E-42 T 28-03-2018 CU254_RS19570 0197d0f5a7f9260289442f1aa308ca0e 145 SMART SM00347 26 126 2.6E-15 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS19570 0197d0f5a7f9260289442f1aa308ca0e 145 SUPERFAMILY SSF46785 9 140 6.45E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS19570 0197d0f5a7f9260289442f1aa308ca0e 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 116 136 2.4E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS19570 0197d0f5a7f9260289442f1aa308ca0e 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 50 66 2.4E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS19570 0197d0f5a7f9260289442f1aa308ca0e 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 67 82 2.4E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS19570 0197d0f5a7f9260289442f1aa308ca0e 145 PRINTS PR00598 Bacterial regulatory protein MarR family signature 86 102 2.4E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS19570 0197d0f5a7f9260289442f1aa308ca0e 145 Gene3D G3DSA:1.10.10.10 2 145 2.8E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS19570 0197d0f5a7f9260289442f1aa308ca0e 145 Pfam PF01047 MarR family 35 90 1.4E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS04565 c8f483ad417bad43ed9cce10ccbd92d4 541 Pfam PF17482 Phage tail sheath C-terminal domain 430 533 3.6E-11 T 28-03-2018 IPR020287 Tail sheath protein, C-terminal domain CU254_RS04565 c8f483ad417bad43ed9cce10ccbd92d4 541 Pfam PF04984 Phage tail sheath protein subtilisin-like domain 291 421 2.5E-12 T 28-03-2018 IPR035089 Tail sheath protein, subtilisin-like domain CU254_RS36070 0990b5df59e79b5fc3df7d8a8cb82e7f 479 SUPERFAMILY SSF53067 241 468 3.67E-25 T 28-03-2018 CU254_RS36070 0990b5df59e79b5fc3df7d8a8cb82e7f 479 SUPERFAMILY SSF53067 7 242 4.53E-36 T 28-03-2018 CU254_RS36070 0990b5df59e79b5fc3df7d8a8cb82e7f 479 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 6 238 9.0E-26 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CU254_RS36070 0990b5df59e79b5fc3df7d8a8cb82e7f 479 Gene3D G3DSA:3.30.420.40 236 471 2.2E-33 T 28-03-2018 CU254_RS36070 0990b5df59e79b5fc3df7d8a8cb82e7f 479 Gene3D G3DSA:3.30.420.40 1 235 4.0E-45 T 28-03-2018 CU254_RS36070 0990b5df59e79b5fc3df7d8a8cb82e7f 479 PIRSF PIRSF000538 3 472 3.9E-59 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CU254_RS36070 0990b5df59e79b5fc3df7d8a8cb82e7f 479 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 252 422 2.6E-17 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CU254_RS05970 84b8f839019598c92d47eade925bb5ac 874 Gene3D G3DSA:1.25.40.10 332 805 0.13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS05970 84b8f839019598c92d47eade925bb5ac 874 Gene3D G3DSA:3.40.50.300 12 300 0.0017 T 28-03-2018 CU254_RS05970 84b8f839019598c92d47eade925bb5ac 874 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 840 852 2.7E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS05970 84b8f839019598c92d47eade925bb5ac 874 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 824 840 2.7E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS05970 84b8f839019598c92d47eade925bb5ac 874 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 810 824 2.7E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS05970 84b8f839019598c92d47eade925bb5ac 874 Pfam PF00196 Bacterial regulatory proteins, luxR family 809 861 3.3E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS05970 84b8f839019598c92d47eade925bb5ac 874 Gene3D G3DSA:1.10.10.10 806 869 7.1E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS05970 84b8f839019598c92d47eade925bb5ac 874 SMART SM00421 807 864 3.3E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS05970 84b8f839019598c92d47eade925bb5ac 874 SUPERFAMILY SSF46894 802 866 6.46E-16 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS20955 fe64b3d283de0896ab10dddcbe9f5cfc 275 Pfam PF00561 alpha/beta hydrolase fold 23 141 7.3E-20 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS20955 fe64b3d283de0896ab10dddcbe9f5cfc 275 Gene3D G3DSA:3.40.50.1820 4 270 1.6E-40 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS20955 fe64b3d283de0896ab10dddcbe9f5cfc 275 PRINTS PR00111 Alpha/beta hydrolase fold signature 48 63 3.8E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS20955 fe64b3d283de0896ab10dddcbe9f5cfc 275 PRINTS PR00111 Alpha/beta hydrolase fold signature 106 119 3.8E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS20955 fe64b3d283de0896ab10dddcbe9f5cfc 275 SUPERFAMILY SSF53474 5 268 2.03E-56 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS20955 fe64b3d283de0896ab10dddcbe9f5cfc 275 PRINTS PR00412 Epoxide hydrolase signature 106 119 5.5E-5 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS20955 fe64b3d283de0896ab10dddcbe9f5cfc 275 PRINTS PR00412 Epoxide hydrolase signature 29 47 5.5E-5 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS12895 33b8d17acbb78ba3a0339dba7decec35 462 Pfam PF01039 Carboxyl transferase domain 43 448 1.3E-108 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 CU254_RS12895 33b8d17acbb78ba3a0339dba7decec35 462 Gene3D G3DSA:3.90.226.10 20 210 2.4E-39 T 28-03-2018 CU254_RS12895 33b8d17acbb78ba3a0339dba7decec35 462 SUPERFAMILY SSF52096 177 447 2.11E-61 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS12895 33b8d17acbb78ba3a0339dba7decec35 462 Gene3D G3DSA:3.90.226.10 211 448 2.2E-56 T 28-03-2018 CU254_RS12895 33b8d17acbb78ba3a0339dba7decec35 462 SUPERFAMILY SSF52096 15 207 3.13E-40 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS32060 49ee305dece25594be5349647e74e85b 393 Gene3D G3DSA:1.10.10.60 197 239 1.6E-16 T 28-03-2018 CU254_RS32060 49ee305dece25594be5349647e74e85b 393 ProSitePatterns PS01081 TetR-type HTH domain signature. 230 261 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CU254_RS32060 49ee305dece25594be5349647e74e85b 393 SUPERFAMILY SSF46689 211 284 1.25E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS32060 49ee305dece25594be5349647e74e85b 393 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 239 262 7.4E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS32060 49ee305dece25594be5349647e74e85b 393 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 218 231 7.4E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS32060 49ee305dece25594be5349647e74e85b 393 Gene3D G3DSA:1.10.357.10 3 196 1.1E-32 T 28-03-2018 CU254_RS32060 49ee305dece25594be5349647e74e85b 393 Pfam PF00440 Bacterial regulatory proteins, tetR family 219 264 2.4E-17 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS32060 49ee305dece25594be5349647e74e85b 393 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 63 3.8E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS32060 49ee305dece25594be5349647e74e85b 393 Gene3D G3DSA:1.10.260.40 240 280 4.5E-13 T 28-03-2018 CU254_RS32060 49ee305dece25594be5349647e74e85b 393 SUPERFAMILY SSF46689 6 90 8.51E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS32060 49ee305dece25594be5349647e74e85b 393 Gene3D G3DSA:1.10.357.10 281 391 0.0027 T 28-03-2018 CU254_RS39125 8f1ebe5622e964ff1a0a388fa30a8b09 441 Gene3D G3DSA:3.30.565.10 315 441 3.7E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS39125 8f1ebe5622e964ff1a0a388fa30a8b09 441 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 353 441 2.0E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS39125 8f1ebe5622e964ff1a0a388fa30a8b09 441 SUPERFAMILY SSF55874 333 441 1.57E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS37435 31ded33bac03233eadf191f285c9b6e8 304 SUPERFAMILY SSF161098 33 292 9.16E-40 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS37435 31ded33bac03233eadf191f285c9b6e8 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 303 1.4E-26 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS37435 31ded33bac03233eadf191f285c9b6e8 304 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 27 297 6.5E-79 T 28-03-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 CU254_RS37435 31ded33bac03233eadf191f285c9b6e8 304 Gene3D G3DSA:1.10.3720.10 14 293 7.2E-42 T 28-03-2018 CU254_RS02340 493fcd7afc5d57bc734d4dd6fe56318d 387 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 22 366 7.4E-96 T 28-03-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001 CU254_RS02340 493fcd7afc5d57bc734d4dd6fe56318d 387 SUPERFAMILY SSF53756 2 371 1.02E-102 T 28-03-2018 CU254_RS02340 493fcd7afc5d57bc734d4dd6fe56318d 387 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 2 359 1.3E-112 T 28-03-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 CU254_RS02340 493fcd7afc5d57bc734d4dd6fe56318d 387 Gene3D G3DSA:3.40.50.2000 210 346 4.0E-37 T 28-03-2018 CU254_RS02340 493fcd7afc5d57bc734d4dd6fe56318d 387 Gene3D G3DSA:3.40.50.2000 2 209 1.0E-56 T 28-03-2018 CU254_RS14900 c6f7c21de0ed7695c0dd5ab8d26818b1 384 Gene3D G3DSA:3.40.50.1820 2 384 3.8E-80 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS14900 c6f7c21de0ed7695c0dd5ab8d26818b1 384 Pfam PF06441 Epoxide hydrolase N terminus 9 116 1.4E-31 T 28-03-2018 IPR010497 Epoxide hydrolase, N-terminal KEGG: 00980+3.3.2.9|Reactome: R-HSA-211945 CU254_RS14900 c6f7c21de0ed7695c0dd5ab8d26818b1 384 SUPERFAMILY SSF53474 6 378 1.26E-96 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS14900 c6f7c21de0ed7695c0dd5ab8d26818b1 384 PRINTS PR00412 Epoxide hydrolase signature 133 148 2.5E-12 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS14900 c6f7c21de0ed7695c0dd5ab8d26818b1 384 PRINTS PR00412 Epoxide hydrolase signature 355 377 2.5E-12 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS14900 c6f7c21de0ed7695c0dd5ab8d26818b1 384 PRINTS PR00412 Epoxide hydrolase signature 178 191 2.5E-12 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS14900 c6f7c21de0ed7695c0dd5ab8d26818b1 384 PRINTS PR00412 Epoxide hydrolase signature 107 125 2.5E-12 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS14900 c6f7c21de0ed7695c0dd5ab8d26818b1 384 PRINTS PR00412 Epoxide hydrolase signature 192 205 2.5E-12 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS14900 c6f7c21de0ed7695c0dd5ab8d26818b1 384 PIRSF PIRSF001112 2 383 8.4E-110 T 28-03-2018 IPR016292 Epoxide hydrolase GO:0033961 KEGG: 00980+3.3.2.9|Reactome: R-HSA-211945 CU254_RS23060 8b783888ee7777de515a2c88e4ddb763 213 Gene3D G3DSA:3.40.50.1950 7 201 1.7E-51 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CU254_RS23060 8b783888ee7777de515a2c88e4ddb763 213 Pfam PF02441 Flavoprotein 8 169 3.6E-22 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CU254_RS23060 8b783888ee7777de515a2c88e4ddb763 213 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 8 188 5.8E-69 T 28-03-2018 IPR004507 Flavin prenyltransferase UbiX/Pad1 CU254_RS23060 8b783888ee7777de515a2c88e4ddb763 213 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 7 190 35.801 T 28-03-2018 IPR004507 Flavin prenyltransferase UbiX/Pad1 CU254_RS23060 8b783888ee7777de515a2c88e4ddb763 213 SUPERFAMILY SSF52507 7 189 9.16E-59 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CU254_RS04835 8e4800d147f7bd53eefa86160fe137ff 166 SUPERFAMILY SSF46785 8 162 8.86E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS04835 8e4800d147f7bd53eefa86160fe137ff 166 Pfam PF03551 Transcriptional regulator PadR-like family 11 81 9.9E-8 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CU254_RS04835 8e4800d147f7bd53eefa86160fe137ff 166 Gene3D G3DSA:1.10.10.10 2 92 4.1E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS05750 632cc52a3c8f8f2e0d4573f955b7a6af 724 SMART SM01043 103 254 1.1E-36 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CU254_RS05750 632cc52a3c8f8f2e0d4573f955b7a6af 724 Gene3D G3DSA:1.25.40.10 105 272 2.8E-18 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS05750 632cc52a3c8f8f2e0d4573f955b7a6af 724 Gene3D G3DSA:1.10.10.10 12 104 2.5E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS05750 632cc52a3c8f8f2e0d4573f955b7a6af 724 PRINTS PR00364 Disease resistance protein signature 470 484 3.5E-9 T 28-03-2018 CU254_RS05750 632cc52a3c8f8f2e0d4573f955b7a6af 724 PRINTS PR00364 Disease resistance protein signature 303 318 3.5E-9 T 28-03-2018 CU254_RS05750 632cc52a3c8f8f2e0d4573f955b7a6af 724 PRINTS PR00364 Disease resistance protein signature 382 396 3.5E-9 T 28-03-2018 CU254_RS05750 632cc52a3c8f8f2e0d4573f955b7a6af 724 Pfam PF00486 Transcriptional regulatory protein, C terminal 23 96 1.1E-4 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS05750 632cc52a3c8f8f2e0d4573f955b7a6af 724 SUPERFAMILY SSF48452 98 276 2.81E-27 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS05750 632cc52a3c8f8f2e0d4573f955b7a6af 724 Pfam PF03704 Bacterial transcriptional activator domain 103 254 7.5E-32 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CU254_RS05750 632cc52a3c8f8f2e0d4573f955b7a6af 724 SUPERFAMILY SSF46894 7 96 8.22E-8 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS05750 632cc52a3c8f8f2e0d4573f955b7a6af 724 Pfam PF00931 NB-ARC domain 294 482 2.9E-6 T 28-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 CU254_RS05750 632cc52a3c8f8f2e0d4573f955b7a6af 724 Gene3D G3DSA:3.40.50.300 273 425 1.9E-12 T 28-03-2018 CU254_RS05750 632cc52a3c8f8f2e0d4573f955b7a6af 724 SUPERFAMILY SSF52540 270 537 4.7E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS00195 7de0d0e0188748e709e9f3c2c17d34a1 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 6.8E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS00195 7de0d0e0188748e709e9f3c2c17d34a1 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 6.8E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS00195 7de0d0e0188748e709e9f3c2c17d34a1 198 SUPERFAMILY SSF48498 81 195 2.2E-19 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS00195 7de0d0e0188748e709e9f3c2c17d34a1 198 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 85 191 3.7E-15 T 28-03-2018 CU254_RS00195 7de0d0e0188748e709e9f3c2c17d34a1 198 Gene3D G3DSA:1.10.10.60 1 61 4.7E-17 T 28-03-2018 CU254_RS00195 7de0d0e0188748e709e9f3c2c17d34a1 198 SUPERFAMILY SSF46689 5 82 1.85E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS00195 7de0d0e0188748e709e9f3c2c17d34a1 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 64 1.6E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS00195 7de0d0e0188748e709e9f3c2c17d34a1 198 Gene3D G3DSA:1.10.357.10 62 198 2.3E-19 T 28-03-2018 CU254_RS02265 fd7e23494620afac21b71d90b42a0ca5 356 SUPERFAMILY SSF53474 39 339 1.31E-50 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS02265 fd7e23494620afac21b71d90b42a0ca5 356 Pfam PF12697 Alpha/beta hydrolase family 73 331 3.8E-22 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS02265 fd7e23494620afac21b71d90b42a0ca5 356 Gene3D G3DSA:3.40.50.1820 43 342 8.2E-49 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS39900 5ad19c334b77d880bc57332eed39ddaa 563 Pfam PF04542 Sigma-70 region 2 35 93 5.4E-9 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS39900 5ad19c334b77d880bc57332eed39ddaa 563 Pfam PF13490 Putative zinc-finger 199 233 1.9E-8 T 28-03-2018 IPR027383 Putative zinc-finger CU254_RS39900 5ad19c334b77d880bc57332eed39ddaa 563 SUPERFAMILY SSF88659 126 183 1.12E-5 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS39900 5ad19c334b77d880bc57332eed39ddaa 563 Gene3D G3DSA:1.10.1740.10 16 98 4.5E-17 T 28-03-2018 CU254_RS39900 5ad19c334b77d880bc57332eed39ddaa 563 SUPERFAMILY SSF88946 10 109 1.07E-16 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS27855 98435ba0a592cc1f9133902add63829f 369 SUPERFAMILY SSF46689 24 83 1.33E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS27855 98435ba0a592cc1f9133902add63829f 369 Pfam PF00440 Bacterial regulatory proteins, tetR family 28 73 7.0E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS27855 98435ba0a592cc1f9133902add63829f 369 Gene3D G3DSA:1.10.357.10 85 369 2.5E-53 T 28-03-2018 CU254_RS27855 98435ba0a592cc1f9133902add63829f 369 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 89 209 2.1E-12 T 28-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 CU254_RS27855 98435ba0a592cc1f9133902add63829f 369 SUPERFAMILY SSF48498 91 218 1.33E-17 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS27855 98435ba0a592cc1f9133902add63829f 369 Gene3D G3DSA:1.10.10.60 15 83 3.1E-12 T 28-03-2018 CU254_RS38010 eec1f3d152ff880f0cb2bd2affeb2d97 273 Gene3D G3DSA:3.20.20.30 13 273 4.0E-26 T 28-03-2018 CU254_RS38010 eec1f3d152ff880f0cb2bd2affeb2d97 273 Pfam PF00296 Luciferase-like monooxygenase 21 121 4.3E-12 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS38010 eec1f3d152ff880f0cb2bd2affeb2d97 273 TIGRFAM TIGR03620 F420_MSMEG_4141: probable F420-dependent oxidoreductase, MSMEG_4141 family 5 269 1.1E-109 T 28-03-2018 IPR019922 Luciferase-like, F420-dependent oxidoreductase, MSMEG4141, predicted CU254_RS38010 eec1f3d152ff880f0cb2bd2affeb2d97 273 SUPERFAMILY SSF51679 19 264 4.04E-33 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS37975 0d9a8f274a8ffdf07ed1d6db6b61956b 168 Gene3D G3DSA:3.40.630.30 6 153 3.4E-24 T 28-03-2018 CU254_RS37975 0d9a8f274a8ffdf07ed1d6db6b61956b 168 Pfam PF00583 Acetyltransferase (GNAT) family 35 144 1.4E-12 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS37975 0d9a8f274a8ffdf07ed1d6db6b61956b 168 SUPERFAMILY SSF55729 8 150 3.04E-24 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS09580 1e6e4e35ec9dc6c593a75cf9b639aac4 412 SUPERFAMILY SSF47413 8 72 2.45E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS09580 1e6e4e35ec9dc6c593a75cf9b639aac4 412 Pfam PF13560 Helix-turn-helix domain 10 66 2.2E-13 T 28-03-2018 CU254_RS09580 1e6e4e35ec9dc6c593a75cf9b639aac4 412 Gene3D G3DSA:1.25.40.10 145 408 1.4E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS09580 1e6e4e35ec9dc6c593a75cf9b639aac4 412 Gene3D G3DSA:1.10.260.40 6 78 1.8E-15 T 28-03-2018 CU254_RS09580 1e6e4e35ec9dc6c593a75cf9b639aac4 412 SMART SM00530 13 69 6.7E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS06170 8d4ffed25e35feee493dd2fd00b5edc7 442 ProSitePatterns PS00146 Beta-lactamase class-A active site. 54 69 - T 28-03-2018 IPR023650 Beta-lactamase, class-A active site KEGG: 00311+3.5.2.6 CU254_RS06170 8d4ffed25e35feee493dd2fd00b5edc7 442 SUPERFAMILY SSF56601 4 323 5.8E-79 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CU254_RS06170 8d4ffed25e35feee493dd2fd00b5edc7 442 Gene3D G3DSA:3.40.710.10 2 329 4.0E-75 T 28-03-2018 CU254_RS06170 8d4ffed25e35feee493dd2fd00b5edc7 442 Pfam PF00144 Beta-lactamase 16 319 1.2E-65 T 28-03-2018 IPR001466 Beta-lactamase-related CU254_RS24900 af8794b19e621092a544c8593bc3f7be 321 Gene3D G3DSA:2.40.30.30 188 321 4.6E-38 T 28-03-2018 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 Reactome: R-HSA-196843 CU254_RS24900 af8794b19e621092a544c8593bc3f7be 321 Gene3D G3DSA:3.40.50.620 1 187 1.6E-43 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS24900 af8794b19e621092a544c8593bc3f7be 321 Pfam PF06574 FAD synthetase 16 151 3.4E-50 T 28-03-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 CU254_RS24900 af8794b19e621092a544c8593bc3f7be 321 SUPERFAMILY SSF82114 182 318 3.27E-36 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CU254_RS24900 af8794b19e621092a544c8593bc3f7be 321 Pfam PF01687 Riboflavin kinase 192 317 1.9E-31 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CU254_RS24900 af8794b19e621092a544c8593bc3f7be 321 SUPERFAMILY SSF52374 16 183 1.47E-31 T 28-03-2018 CU254_RS24900 af8794b19e621092a544c8593bc3f7be 321 SMART SM00904 191 318 1.3E-43 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CU254_RS24900 af8794b19e621092a544c8593bc3f7be 321 PIRSF PIRSF004491 8 321 5.2E-90 T 28-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 CU254_RS24900 af8794b19e621092a544c8593bc3f7be 321 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 19 316 3.1E-67 T 28-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 CU254_RS00730 aba5129ceb9f407d70cc96ccd3e47cde 305 Pfam PF00753 Metallo-beta-lactamase superfamily 28 210 4.4E-23 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS00730 aba5129ceb9f407d70cc96ccd3e47cde 305 SUPERFAMILY SSF56281 7 261 1.82E-53 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS00730 aba5129ceb9f407d70cc96ccd3e47cde 305 Gene3D G3DSA:3.60.15.10 4 236 1.6E-32 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS00730 aba5129ceb9f407d70cc96ccd3e47cde 305 SMART SM00849 30 210 1.6E-21 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS30875 4ee356cdd0590756774b67d801ffdbda 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 249 6.9E-58 T 28-03-2018 CU254_RS30875 4ee356cdd0590756774b67d801ffdbda 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 4.7E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS30875 4ee356cdd0590756774b67d801ffdbda 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 4.7E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS30875 4ee356cdd0590756774b67d801ffdbda 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 4.7E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS30875 4ee356cdd0590756774b67d801ffdbda 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 4.7E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS30875 4ee356cdd0590756774b67d801ffdbda 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 4.7E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS30875 4ee356cdd0590756774b67d801ffdbda 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 4.7E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS30875 4ee356cdd0590756774b67d801ffdbda 253 Gene3D G3DSA:3.40.50.720 1 46 1.6E-10 T 28-03-2018 CU254_RS30875 4ee356cdd0590756774b67d801ffdbda 253 Gene3D G3DSA:3.40.50.720 47 253 1.4E-60 T 28-03-2018 CU254_RS30875 4ee356cdd0590756774b67d801ffdbda 253 SUPERFAMILY SSF51735 8 251 1.86E-74 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS30875 4ee356cdd0590756774b67d801ffdbda 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS30875 4ee356cdd0590756774b67d801ffdbda 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 3.6E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS30875 4ee356cdd0590756774b67d801ffdbda 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 3.6E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS30875 4ee356cdd0590756774b67d801ffdbda 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 3.6E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS30875 4ee356cdd0590756774b67d801ffdbda 253 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 185 0.0018 T 28-03-2018 CU254_RS38965 3b475cf390036e38da1b84419ef702e9 200 Pfam PF12079 Protein of unknown function (DUF3558) 19 194 4.7E-28 T 28-03-2018 IPR024520 Protein of unknown function DUF3558 CU254_RS15615 eb2ba678c7a97144c0600e8f241eca86 408 Gene3D G3DSA:3.60.40.10 169 404 8.3E-34 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CU254_RS15615 eb2ba678c7a97144c0600e8f241eca86 408 SUPERFAMILY SSF55781 13 165 5.02E-26 T 28-03-2018 IPR029016 GAF domain-like CU254_RS15615 eb2ba678c7a97144c0600e8f241eca86 408 SMART SM00065 26 171 1.3E-11 T 28-03-2018 IPR003018 GAF domain GO:0005515 CU254_RS15615 eb2ba678c7a97144c0600e8f241eca86 408 SUPERFAMILY SSF81606 193 400 6.8E-6 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CU254_RS15615 eb2ba678c7a97144c0600e8f241eca86 408 SMART SM00331 188 401 3.0E-33 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CU254_RS15615 eb2ba678c7a97144c0600e8f241eca86 408 Pfam PF13185 GAF domain 25 162 1.2E-17 T 28-03-2018 IPR003018 GAF domain GO:0005515 CU254_RS15615 eb2ba678c7a97144c0600e8f241eca86 408 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 216 401 3.7E-42 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CU254_RS15615 eb2ba678c7a97144c0600e8f241eca86 408 Gene3D G3DSA:3.30.450.40 7 168 4.5E-27 T 28-03-2018 IPR029016 GAF domain-like CU254_RS30750 ac0d0da65b4d81c6763ab46f959f8913 138 Gene3D G3DSA:3.30.450.30 6 129 9.2E-41 T 28-03-2018 CU254_RS30750 ac0d0da65b4d81c6763ab46f959f8913 138 SMART SM00960 10 100 3.9E-31 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain CU254_RS30750 ac0d0da65b4d81c6763ab46f959f8913 138 SUPERFAMILY SSF103196 3 129 4.53E-37 T 28-03-2018 CU254_RS30750 ac0d0da65b4d81c6763ab46f959f8913 138 Pfam PF03259 Roadblock/LC7 domain 9 100 8.4E-26 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain CU254_RS09990 fbbcc2a5a112d15bda42ca9252b07115 381 Pfam PF14606 GDSL-like Lipase/Acylhydrolase family 172 271 1.6E-13 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CU254_RS09990 fbbcc2a5a112d15bda42ca9252b07115 381 Gene3D G3DSA:3.40.50.1110 166 374 5.1E-26 T 28-03-2018 CU254_RS09990 fbbcc2a5a112d15bda42ca9252b07115 381 SUPERFAMILY SSF52266 164 371 5.89E-26 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CU254_RS36965 ffe5e0e28b15dd42450fd61033185055 322 SUPERFAMILY SSF46785 2 58 2.49E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS36965 ffe5e0e28b15dd42450fd61033185055 322 PIRSF PIRSF016838 1 322 7.0E-22 T 28-03-2018 IPR028349 Protein PafC CU254_RS36965 ffe5e0e28b15dd42450fd61033185055 322 Gene3D G3DSA:1.10.10.10 1 64 3.4E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS36965 ffe5e0e28b15dd42450fd61033185055 322 Pfam PF13280 WYL domain 140 317 2.6E-39 T 28-03-2018 IPR026881 WYL domain CU254_RS36965 ffe5e0e28b15dd42450fd61033185055 322 ProSitePatterns PS00894 DeoR-type HTH domain signature. 5 39 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CU254_RS36965 ffe5e0e28b15dd42450fd61033185055 322 SMART SM00420 5 61 0.0052 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CU254_RS36965 ffe5e0e28b15dd42450fd61033185055 322 Pfam PF08279 HTH domain 13 59 4.5E-10 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 CU254_RS15475 c5f3c81223f7e2243a05ad0deebb4c17 331 Pfam PF01384 Phosphate transporter family 21 319 1.6E-82 T 28-03-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 CU254_RS24375 df6ca0b0ee58e612f475a7885f6680a2 243 Gene3D G3DSA:1.10.150.240 22 104 1.2E-22 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CU254_RS24375 df6ca0b0ee58e612f475a7885f6680a2 243 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 101 213 2.7E-14 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CU254_RS24375 df6ca0b0ee58e612f475a7885f6680a2 243 SUPERFAMILY SSF56784 8 241 5.56E-40 T 28-03-2018 IPR023214 HAD-like domain CU254_RS24375 df6ca0b0ee58e612f475a7885f6680a2 243 Pfam PF13419 Haloacid dehalogenase-like hydrolase 11 209 3.0E-17 T 28-03-2018 IPR023214 HAD-like domain CU254_RS24375 df6ca0b0ee58e612f475a7885f6680a2 243 Gene3D G3DSA:3.40.50.1000 105 243 1.1E-24 T 28-03-2018 IPR023214 HAD-like domain CU254_RS24375 df6ca0b0ee58e612f475a7885f6680a2 243 TIGRFAM TIGR02009 PGMB-YQAB-SF: beta-phosphoglucomutase family hydrolase 8 210 6.2E-51 T 28-03-2018 IPR010976 Beta-phosphoglucomutase hydrolase CU254_RS04440 6c6a7859a71b15c4b1324c1858581e54 177 SUPERFAMILY SSF46767 86 168 4.97E-26 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CU254_RS04440 6c6a7859a71b15c4b1324c1858581e54 177 SUPERFAMILY SSF53155 1 83 3.73E-11 T 28-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CU254_RS04440 6c6a7859a71b15c4b1324c1858581e54 177 Gene3D G3DSA:3.30.160.70 1 83 1.1E-11 T 28-03-2018 CU254_RS04440 6c6a7859a71b15c4b1324c1858581e54 177 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 87 167 5.9E-24 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CU254_RS04440 6c6a7859a71b15c4b1324c1858581e54 177 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 87 168 1.0E-28 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CU254_RS04440 6c6a7859a71b15c4b1324c1858581e54 177 Gene3D G3DSA:1.10.10.10 84 174 1.2E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS04440 6c6a7859a71b15c4b1324c1858581e54 177 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 136 142 - T 28-03-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CU254_RS28240 d2f547defe806fda8bf018fb73420d56 256 SMART SM00382 31 222 8.4E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS28240 d2f547defe806fda8bf018fb73420d56 256 SUPERFAMILY SSF52540 8 227 3.45E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS28240 d2f547defe806fda8bf018fb73420d56 256 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS28240 d2f547defe806fda8bf018fb73420d56 256 Pfam PF00005 ABC transporter 23 165 2.1E-21 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS28240 d2f547defe806fda8bf018fb73420d56 256 Gene3D G3DSA:3.40.50.300 5 233 1.2E-50 T 28-03-2018 CU254_RS34105 6938c8a946507c5d454b2968969f240b 586 SUPERFAMILY SSF49785 26 149 4.82E-12 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS34105 6938c8a946507c5d454b2968969f240b 586 Gene3D G3DSA:2.60.120.260 24 149 1.5E-24 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS34105 6938c8a946507c5d454b2968969f240b 586 Pfam PF02018 Carbohydrate binding domain 26 135 9.7E-11 T 28-03-2018 IPR003305 Carbohydrate-binding, CenC-like GO:0016798 CU254_RS34105 6938c8a946507c5d454b2968969f240b 586 SUPERFAMILY SSF49265 158 243 4.31E-13 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CU254_RS34105 6938c8a946507c5d454b2968969f240b 586 Gene3D G3DSA:2.60.40.10 158 241 3.7E-13 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS34105 6938c8a946507c5d454b2968969f240b 586 SMART SM00636 252 567 2.1E-6 T 28-03-2018 IPR011583 Chitinase II GO:0008061 CU254_RS34105 6938c8a946507c5d454b2968969f240b 586 SUPERFAMILY SSF51445 252 578 8.99E-55 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS34105 6938c8a946507c5d454b2968969f240b 586 Gene3D G3DSA:3.20.20.80 250 584 5.2E-43 T 28-03-2018 CU254_RS34105 6938c8a946507c5d454b2968969f240b 586 SMART SM00060 160 231 4.4E-7 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CU254_RS34105 6938c8a946507c5d454b2968969f240b 586 Pfam PF00704 Glycosyl hydrolases family 18 254 567 6.7E-26 T 28-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 CU254_RS34105 6938c8a946507c5d454b2968969f240b 586 ProSitePatterns PS01095 Chitinases family 18 active site. 364 372 - T 28-03-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 CU254_RS30585 661d1bef84a0ce49c2cf561263aacd19 125 SUPERFAMILY SSF110857 4 69 3.92E-9 T 28-03-2018 IPR013024 Gamma-glutamyl cyclotransferase-like CU254_RS30585 661d1bef84a0ce49c2cf561263aacd19 125 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 5 92 2.2E-6 T 28-03-2018 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like CU254_RS30585 661d1bef84a0ce49c2cf561263aacd19 125 Gene3D G3DSA:3.10.490.10 1 125 2.7E-23 T 28-03-2018 CU254_RS23405 67c17dbf602bfebc60be5d244bf0c689 560 SUPERFAMILY SSF56425 316 492 5.23E-31 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CU254_RS23405 67c17dbf602bfebc60be5d244bf0c689 560 SUPERFAMILY SSF51905 499 557 1.89E-37 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS23405 67c17dbf602bfebc60be5d244bf0c689 560 SUPERFAMILY SSF51905 192 325 1.89E-37 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS23405 67c17dbf602bfebc60be5d244bf0c689 560 SUPERFAMILY SSF51905 3 131 1.89E-37 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS23405 67c17dbf602bfebc60be5d244bf0c689 560 Gene3D G3DSA:3.50.50.60 387 557 1.8E-15 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS23405 67c17dbf602bfebc60be5d244bf0c689 560 Gene3D G3DSA:3.50.50.60 8 386 1.5E-49 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS23405 67c17dbf602bfebc60be5d244bf0c689 560 Pfam PF00890 FAD binding domain 13 540 2.8E-90 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CU254_RS32620 b6853def4561c777b998efa943ffdbb4 271 Hamap MF_01696 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase [mshB]. 1 271 38.335 T 28-03-2018 IPR017810 Mycothiol biosynthesis protein, MshB GO:0035595 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CU254_RS32620 b6853def4561c777b998efa943ffdbb4 271 Gene3D G3DSA:3.40.50.10320 1 271 2.9E-61 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CU254_RS32620 b6853def4561c777b998efa943ffdbb4 271 SUPERFAMILY SSF102588 1 259 3.14E-60 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CU254_RS32620 b6853def4561c777b998efa943ffdbb4 271 TIGRFAM TIGR03445 mycothiol_MshB: N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase 2 270 5.1E-95 T 28-03-2018 IPR017810 Mycothiol biosynthesis protein, MshB GO:0035595 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CU254_RS32620 b6853def4561c777b998efa943ffdbb4 271 Pfam PF02585 GlcNAc-PI de-N-acetylase 2 152 1.9E-24 T 28-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 CU254_RS13645 c8f8579d871965f68c1da37fca30fff6 283 SUPERFAMILY SSF51735 2 272 4.83E-54 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS13645 c8f8579d871965f68c1da37fca30fff6 283 Gene3D G3DSA:3.40.50.720 1 70 1.2E-17 T 28-03-2018 CU254_RS13645 c8f8579d871965f68c1da37fca30fff6 283 Pfam PF13460 NAD(P)H-binding 7 178 7.4E-24 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS13645 c8f8579d871965f68c1da37fca30fff6 283 Gene3D G3DSA:3.40.50.720 76 279 1.4E-10 T 28-03-2018 CU254_RS01960 21b311700d5600560bfa4f36831528dc 103 Pfam PF00276 Ribosomal protein L23 11 93 5.7E-32 T 28-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 CU254_RS01960 21b311700d5600560bfa4f36831528dc 103 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 10 100 21.413 T 28-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 CU254_RS01960 21b311700d5600560bfa4f36831528dc 103 SUPERFAMILY SSF54189 8 98 2.91E-32 T 28-03-2018 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS01960 21b311700d5600560bfa4f36831528dc 103 ProSitePatterns PS00050 Ribosomal protein L23 signature. 82 97 - T 28-03-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS01960 21b311700d5600560bfa4f36831528dc 103 Gene3D G3DSA:3.30.70.330 7 102 1.0E-31 T 28-03-2018 CU254_RS33880 03f8d797b4268a847b919c8da8e817a4 319 SUPERFAMILY SSF51735 104 283 9.92E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS33880 03f8d797b4268a847b919c8da8e817a4 319 Gene3D G3DSA:3.90.180.10 245 318 0.0014 T 28-03-2018 CU254_RS33880 03f8d797b4268a847b919c8da8e817a4 319 SMART SM00829 10 315 2.1E-27 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CU254_RS33880 03f8d797b4268a847b919c8da8e817a4 319 Pfam PF00107 Zinc-binding dehydrogenase 142 260 1.3E-30 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CU254_RS33880 03f8d797b4268a847b919c8da8e817a4 319 Gene3D G3DSA:3.40.50.720 134 244 8.7E-28 T 28-03-2018 CU254_RS33880 03f8d797b4268a847b919c8da8e817a4 319 SUPERFAMILY SSF50129 1 131 9.59E-30 T 28-03-2018 IPR011032 GroES-like CU254_RS33880 03f8d797b4268a847b919c8da8e817a4 319 Gene3D G3DSA:3.90.180.10 1 133 2.4E-35 T 28-03-2018 CU254_RS33740 e2bd7fa34f1c963b6f4e6916d87b2051 319 Pfam PF00487 Fatty acid desaturase 58 274 1.3E-19 T 28-03-2018 IPR005804 Fatty acid desaturase domain GO:0006629 CU254_RS33740 e2bd7fa34f1c963b6f4e6916d87b2051 319 PRINTS PR00075 Fatty acid desaturase family 1 signature 261 275 2.3E-17 T 28-03-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 CU254_RS33740 e2bd7fa34f1c963b6f4e6916d87b2051 319 PRINTS PR00075 Fatty acid desaturase family 1 signature 218 239 2.3E-17 T 28-03-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 CU254_RS33740 e2bd7fa34f1c963b6f4e6916d87b2051 319 PRINTS PR00075 Fatty acid desaturase family 1 signature 58 80 2.3E-17 T 28-03-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 CU254_RS33740 e2bd7fa34f1c963b6f4e6916d87b2051 319 PRINTS PR00075 Fatty acid desaturase family 1 signature 81 101 2.3E-17 T 28-03-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 CU254_RS41980 bbb232f422b0223a61bbd602b90c82c9 176 Pfam PF14525 AraC-binding-like domain 33 151 1.0E-6 T 28-03-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like CU254_RS18715 8163cfb46eb7ef62700bff0011422c58 223 Gene3D G3DSA:1.20.120.530 80 221 5.7E-25 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS18715 8163cfb46eb7ef62700bff0011422c58 223 SMART SM00895 87 206 4.6E-13 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS18715 8163cfb46eb7ef62700bff0011422c58 223 Gene3D G3DSA:1.10.10.10 4 79 5.0E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS18715 8163cfb46eb7ef62700bff0011422c58 223 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 77 1.0E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS18715 8163cfb46eb7ef62700bff0011422c58 223 Pfam PF07729 FCD domain 88 205 9.6E-18 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS18715 8163cfb46eb7ef62700bff0011422c58 223 SMART SM00345 19 77 2.7E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS18715 8163cfb46eb7ef62700bff0011422c58 223 SUPERFAMILY SSF46785 10 81 2.62E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS18715 8163cfb46eb7ef62700bff0011422c58 223 SUPERFAMILY SSF48008 83 213 3.92E-19 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS18565 55ba48b468fd70c6e7c5777ddb9e4a3c 429 PRINTS PR00758 Arsenical pump membrane protein signature 365 390 7.1E-13 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CU254_RS18565 55ba48b468fd70c6e7c5777ddb9e4a3c 429 PRINTS PR00758 Arsenical pump membrane protein signature 103 127 7.1E-13 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CU254_RS18565 55ba48b468fd70c6e7c5777ddb9e4a3c 429 PRINTS PR00758 Arsenical pump membrane protein signature 276 300 7.1E-13 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CU254_RS18565 55ba48b468fd70c6e7c5777ddb9e4a3c 429 PRINTS PR00758 Arsenical pump membrane protein signature 398 422 7.1E-13 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CU254_RS18565 55ba48b468fd70c6e7c5777ddb9e4a3c 429 PRINTS PR00758 Arsenical pump membrane protein signature 219 244 7.1E-13 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CU254_RS18565 55ba48b468fd70c6e7c5777ddb9e4a3c 429 Pfam PF03600 Citrate transporter 14 369 5.6E-55 T 28-03-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 CU254_RS07970 cb63323da4eacd4c6f66d7f34e3471b4 79 SUPERFAMILY SSF54814 18 63 4.05E-8 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CU254_RS07970 cb63323da4eacd4c6f66d7f34e3471b4 79 Pfam PF13083 KH domain 6 66 1.2E-18 T 28-03-2018 CU254_RS07970 cb63323da4eacd4c6f66d7f34e3471b4 79 Gene3D G3DSA:3.30.300.20 1 76 6.5E-13 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CU254_RS07970 cb63323da4eacd4c6f66d7f34e3471b4 79 Hamap MF_00088 UPF0109 protein . 4 75 20.513 T 28-03-2018 IPR020627 Uncharacterised protein family UPF0109 CU254_RS17450 83dc94bf2fbd44e74e090316e394ac74 457 SUPERFAMILY SSF51905 294 354 1.94E-27 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS17450 83dc94bf2fbd44e74e090316e394ac74 457 SUPERFAMILY SSF51905 2 184 1.94E-27 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS17450 83dc94bf2fbd44e74e090316e394ac74 457 Gene3D G3DSA:3.50.50.60 1 334 1.8E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS22445 cad635760462c7db5ffb9d6995f51448 401 Gene3D G3DSA:3.90.1150.10 1 175 2.8E-49 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS22445 cad635760462c7db5ffb9d6995f51448 401 Pfam PF00202 Aminotransferase class-III 27 388 3.1E-104 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CU254_RS22445 cad635760462c7db5ffb9d6995f51448 401 Gene3D G3DSA:3.90.1150.10 290 399 3.6E-16 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS22445 cad635760462c7db5ffb9d6995f51448 401 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 18 392 1.6E-138 T 28-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 CU254_RS22445 cad635760462c7db5ffb9d6995f51448 401 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 220 257 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CU254_RS22445 cad635760462c7db5ffb9d6995f51448 401 Gene3D G3DSA:3.40.640.10 176 289 6.7E-43 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS22445 cad635760462c7db5ffb9d6995f51448 401 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 15 393 43.017 T 28-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 CU254_RS22445 cad635760462c7db5ffb9d6995f51448 401 SUPERFAMILY SSF53383 10 393 5.15E-122 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS22445 cad635760462c7db5ffb9d6995f51448 401 PIRSF PIRSF000521 170 395 3.6E-27 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CU254_RS22445 cad635760462c7db5ffb9d6995f51448 401 PIRSF PIRSF000521 124 158 0.1 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CU254_RS22445 cad635760462c7db5ffb9d6995f51448 401 PIRSF PIRSF000521 26 130 3.2E-8 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CU254_RS17630 2ec0b826292a2f83c334e6d70fcfd79f 212 SUPERFAMILY SSF52499 7 207 2.62E-60 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CU254_RS17630 2ec0b826292a2f83c334e6d70fcfd79f 212 Pfam PF00857 Isochorismatase family 13 204 2.0E-44 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CU254_RS17630 2ec0b826292a2f83c334e6d70fcfd79f 212 Gene3D G3DSA:3.40.50.850 2 211 1.3E-57 T 28-03-2018 CU254_RS10550 5384a27e722a2d383a737971d15049eb 408 Pfam PF00067 Cytochrome P450 287 375 9.8E-14 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS10550 5384a27e722a2d383a737971d15049eb 408 PRINTS PR00359 B-class P450 signature 350 359 5.1E-46 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS10550 5384a27e722a2d383a737971d15049eb 408 PRINTS PR00359 B-class P450 signature 359 370 5.1E-46 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS10550 5384a27e722a2d383a737971d15049eb 408 PRINTS PR00359 B-class P450 signature 165 180 5.1E-46 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS10550 5384a27e722a2d383a737971d15049eb 408 PRINTS PR00359 B-class P450 signature 283 294 5.1E-46 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS10550 5384a27e722a2d383a737971d15049eb 408 PRINTS PR00359 B-class P450 signature 102 113 5.1E-46 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS10550 5384a27e722a2d383a737971d15049eb 408 PRINTS PR00359 B-class P450 signature 148 164 5.1E-46 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS10550 5384a27e722a2d383a737971d15049eb 408 PRINTS PR00359 B-class P450 signature 300 327 5.1E-46 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS10550 5384a27e722a2d383a737971d15049eb 408 PRINTS PR00359 B-class P450 signature 328 343 5.1E-46 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS10550 5384a27e722a2d383a737971d15049eb 408 PRINTS PR00359 B-class P450 signature 204 226 5.1E-46 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS10550 5384a27e722a2d383a737971d15049eb 408 SUPERFAMILY SSF48264 7 407 7.2E-79 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS10550 5384a27e722a2d383a737971d15049eb 408 Gene3D G3DSA:1.10.630.10 4 408 2.9E-59 T 28-03-2018 CU254_RS18315 b2c40e86d4019db07dcc04575dba2caa 400 SUPERFAMILY SSF55718 299 400 1.02E-18 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CU254_RS18315 b2c40e86d4019db07dcc04575dba2caa 400 Gene3D G3DSA:3.40.630.30 1 132 2.7E-7 T 28-03-2018 CU254_RS18315 b2c40e86d4019db07dcc04575dba2caa 400 Hamap MF_01812 UPF0256 protein . 3 400 28.737 T 28-03-2018 IPR022902 N-acetyltransferase Eis CU254_RS18315 b2c40e86d4019db07dcc04575dba2caa 400 Gene3D G3DSA:3.30.1050.10 293 393 8.5E-23 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CU254_RS18315 b2c40e86d4019db07dcc04575dba2caa 400 Pfam PF13530 Sterol carrier protein domain 182 396 3.0E-49 T 28-03-2018 IPR025559 Enhanced intracellular survival protein domain CU254_RS18315 b2c40e86d4019db07dcc04575dba2caa 400 SUPERFAMILY SSF55729 5 298 4.68E-46 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS18315 b2c40e86d4019db07dcc04575dba2caa 400 Gene3D G3DSA:3.40.630.30 133 292 1.6E-39 T 28-03-2018 CU254_RS18315 b2c40e86d4019db07dcc04575dba2caa 400 Pfam PF13527 Acetyltransferase (GNAT) domain 6 130 8.1E-22 T 28-03-2018 CU254_RS30575 81295b3cca6c62d4d51f118c34890237 130 SUPERFAMILY SSF55811 7 127 7.99E-30 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CU254_RS30575 81295b3cca6c62d4d51f118c34890237 130 Gene3D G3DSA:3.90.79.10 2 129 6.4E-30 T 28-03-2018 CU254_RS30575 81295b3cca6c62d4d51f118c34890237 130 PRINTS PR00502 NUDIX hydrolase family signature 46 61 4.8E-9 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CU254_RS30575 81295b3cca6c62d4d51f118c34890237 130 PRINTS PR00502 NUDIX hydrolase family signature 32 46 4.8E-9 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CU254_RS30575 81295b3cca6c62d4d51f118c34890237 130 Pfam PF00293 NUDIX domain 8 119 1.4E-22 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CU254_RS30575 81295b3cca6c62d4d51f118c34890237 130 ProSitePatterns PS00893 Nudix box signature. 37 58 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CU254_RS04025 de9a0a84f924435ebd58c478f8f58a40 455 Gene3D G3DSA:1.20.1250.20 23 222 1.0E-17 T 28-03-2018 CU254_RS04025 de9a0a84f924435ebd58c478f8f58a40 455 Pfam PF07690 Major Facilitator Superfamily 49 401 1.1E-22 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS04025 de9a0a84f924435ebd58c478f8f58a40 455 SUPERFAMILY SSF103473 17 441 4.71E-47 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS04025 de9a0a84f924435ebd58c478f8f58a40 455 Gene3D G3DSA:1.20.1250.20 228 450 1.3E-22 T 28-03-2018 CU254_RS04860 3b1cffe9d8f6d3b20a403ea9ddf887be 298 Gene3D G3DSA:3.20.20.140 57 291 7.9E-37 T 28-03-2018 CU254_RS04860 3b1cffe9d8f6d3b20a403ea9ddf887be 298 SUPERFAMILY SSF51556 23 296 8.58E-42 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS04860 3b1cffe9d8f6d3b20a403ea9ddf887be 298 Pfam PF04909 Amidohydrolase 24 296 1.6E-28 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CU254_RS07395 ef179ade83190e81f9b810c398d29dae 125 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 124 6.6E-46 T 28-03-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 CU254_RS07395 ef179ade83190e81f9b810c398d29dae 125 SUPERFAMILY SSF51230 3 123 3.14E-40 T 28-03-2018 IPR011053 Single hybrid motif CU254_RS07395 ef179ade83190e81f9b810c398d29dae 125 Gene3D G3DSA:2.40.50.100 5 125 1.6E-43 T 28-03-2018 CU254_RS07395 ef179ade83190e81f9b810c398d29dae 125 Pfam PF01597 Glycine cleavage H-protein 7 124 1.2E-40 T 28-03-2018 IPR033753 Glycine cleavage system H-protein/Simiate CU254_RS07395 ef179ade83190e81f9b810c398d29dae 125 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 47 76 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CU254_RS07395 ef179ade83190e81f9b810c398d29dae 125 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 4 123 38.013 T 28-03-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 CU254_RS20880 c65b89caebe66ff612bc7826b416cac8 297 Pfam PF00294 pfkB family carbohydrate kinase 4 283 7.0E-59 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CU254_RS20880 c65b89caebe66ff612bc7826b416cac8 297 PRINTS PR00990 Ribokinase signature 168 183 1.1E-27 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CU254_RS20880 c65b89caebe66ff612bc7826b416cac8 297 PRINTS PR00990 Ribokinase signature 106 119 1.1E-27 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CU254_RS20880 c65b89caebe66ff612bc7826b416cac8 297 PRINTS PR00990 Ribokinase signature 207 218 1.1E-27 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CU254_RS20880 c65b89caebe66ff612bc7826b416cac8 297 PRINTS PR00990 Ribokinase signature 7 28 1.1E-27 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CU254_RS20880 c65b89caebe66ff612bc7826b416cac8 297 PRINTS PR00990 Ribokinase signature 34 53 1.1E-27 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CU254_RS20880 c65b89caebe66ff612bc7826b416cac8 297 Gene3D G3DSA:3.40.1190.20 1 297 4.1E-74 T 28-03-2018 IPR029056 Ribokinase-like CU254_RS20880 c65b89caebe66ff612bc7826b416cac8 297 Hamap MF_01987 Ribokinase [rbsK]. 3 290 24.309 T 28-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 CU254_RS20880 c65b89caebe66ff612bc7826b416cac8 297 SUPERFAMILY SSF53613 4 290 2.49E-70 T 28-03-2018 IPR029056 Ribokinase-like CU254_RS19675 09b81da7b77ef16127dc23f61bc8b2a4 242 Gene3D G3DSA:3.30.530.20 8 157 2.0E-16 T 28-03-2018 IPR023393 START-like domain CU254_RS19675 09b81da7b77ef16127dc23f61bc8b2a4 242 SUPERFAMILY SSF55961 12 138 3.9E-15 T 28-03-2018 CU254_RS20180 009121517b0f3c8dddf30085505a4552 229 Pfam PF00881 Nitroreductase family 33 201 1.4E-22 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CU254_RS20180 009121517b0f3c8dddf30085505a4552 229 Gene3D G3DSA:3.40.109.10 8 224 3.0E-35 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CU254_RS20180 009121517b0f3c8dddf30085505a4552 229 SUPERFAMILY SSF55469 26 221 1.23E-38 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CU254_RS22055 093040463a7c5660f20bb78651b2e139 309 Gene3D G3DSA:2.40.10.10 96 129 1.4E-5 T 28-03-2018 CU254_RS22055 093040463a7c5660f20bb78651b2e139 309 Gene3D G3DSA:2.40.10.10 208 309 5.2E-19 T 28-03-2018 CU254_RS22055 093040463a7c5660f20bb78651b2e139 309 SUPERFAMILY SSF50494 102 295 2.04E-21 T 28-03-2018 IPR009003 Peptidase S1, PA clan CU254_RS22055 093040463a7c5660f20bb78651b2e139 309 Gene3D G3DSA:2.40.10.10 130 205 2.6E-7 T 28-03-2018 CU254_RS22055 093040463a7c5660f20bb78651b2e139 309 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 136 141 - T 28-03-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 CU254_RS22055 093040463a7c5660f20bb78651b2e139 309 Pfam PF13365 Trypsin-like peptidase domain 128 262 7.4E-9 T 28-03-2018 CU254_RS32120 0ce496ad1a97d64fd939f71b99332d39 351 SUPERFAMILY SSF53474 47 348 1.48E-30 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS32120 0ce496ad1a97d64fd939f71b99332d39 351 Pfam PF06850 PHB de-polymerase C-terminus 257 347 4.0E-6 T 28-03-2018 IPR009656 PHB de-polymerase, C-terminal CU254_RS32120 0ce496ad1a97d64fd939f71b99332d39 351 Gene3D G3DSA:3.40.50.1820 32 350 1.4E-30 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS04720 5e76dec4d8c51363aa518bdd0a43c66e 120 SMART SM00418 32 112 2.8E-33 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS04720 5e76dec4d8c51363aa518bdd0a43c66e 120 Gene3D G3DSA:1.10.10.10 11 112 1.1E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS04720 5e76dec4d8c51363aa518bdd0a43c66e 120 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 34 49 7.6E-23 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS04720 5e76dec4d8c51363aa518bdd0a43c66e 120 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 69 84 7.6E-23 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS04720 5e76dec4d8c51363aa518bdd0a43c66e 120 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 84 99 7.6E-23 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS04720 5e76dec4d8c51363aa518bdd0a43c66e 120 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 56 67 7.6E-23 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS04720 5e76dec4d8c51363aa518bdd0a43c66e 120 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 58 76 - T 28-03-2018 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 CU254_RS04720 5e76dec4d8c51363aa518bdd0a43c66e 120 Pfam PF01022 Bacterial regulatory protein, arsR family 39 87 3.6E-16 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS04720 5e76dec4d8c51363aa518bdd0a43c66e 120 SUPERFAMILY SSF46785 19 111 4.79E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS02905 b319241cb4b3d793d52a4c5dbaec874a 449 Pfam PF01547 Bacterial extracellular solute-binding protein 52 338 7.3E-46 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 CU254_RS02905 b319241cb4b3d793d52a4c5dbaec874a 449 Gene3D G3DSA:3.40.190.10 214 393 1.3E-11 T 28-03-2018 CU254_RS02905 b319241cb4b3d793d52a4c5dbaec874a 449 SUPERFAMILY SSF53850 19 442 2.62E-69 T 28-03-2018 CU254_RS02905 b319241cb4b3d793d52a4c5dbaec874a 449 Gene3D G3DSA:3.40.190.10 33 213 2.0E-36 T 28-03-2018 CU254_RS29040 23b9148f1766e930a5605f412c77fe34 884 Pfam PF13191 AAA ATPase domain 2 159 1.6E-21 T 28-03-2018 CU254_RS29040 23b9148f1766e930a5605f412c77fe34 884 SUPERFAMILY SSF52540 2 218 4.69E-9 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS29040 23b9148f1766e930a5605f412c77fe34 884 Gene3D G3DSA:1.25.40.10 686 817 1.5E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS29040 23b9148f1766e930a5605f412c77fe34 884 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 824 838 2.6E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS29040 23b9148f1766e930a5605f412c77fe34 884 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 854 866 2.6E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS29040 23b9148f1766e930a5605f412c77fe34 884 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 838 854 2.6E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS29040 23b9148f1766e930a5605f412c77fe34 884 Gene3D G3DSA:1.10.10.10 818 877 1.1E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS29040 23b9148f1766e930a5605f412c77fe34 884 Gene3D G3DSA:1.25.40.10 388 684 2.9E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS29040 23b9148f1766e930a5605f412c77fe34 884 SMART SM00421 821 878 9.1E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS29040 23b9148f1766e930a5605f412c77fe34 884 Gene3D G3DSA:3.40.50.300 3 174 1.2E-12 T 28-03-2018 CU254_RS29040 23b9148f1766e930a5605f412c77fe34 884 ProSitePatterns PS00622 LuxR-type HTH domain signature. 838 865 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS29040 23b9148f1766e930a5605f412c77fe34 884 SUPERFAMILY SSF48452 720 788 3.07E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS29040 23b9148f1766e930a5605f412c77fe34 884 SUPERFAMILY SSF48452 614 684 3.07E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS29040 23b9148f1766e930a5605f412c77fe34 884 Pfam PF00196 Bacterial regulatory proteins, luxR family 823 876 6.5E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS29040 23b9148f1766e930a5605f412c77fe34 884 SUPERFAMILY SSF46894 811 875 2.55E-15 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS30540 f894c2098bbb396953cba32fc6bd5de1 314 SUPERFAMILY SSF56281 20 241 2.66E-33 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS30540 f894c2098bbb396953cba32fc6bd5de1 314 Pfam PF00753 Metallo-beta-lactamase superfamily 29 217 1.6E-10 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS30540 f894c2098bbb396953cba32fc6bd5de1 314 Gene3D G3DSA:3.60.15.10 11 245 3.7E-25 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS30540 f894c2098bbb396953cba32fc6bd5de1 314 SMART SM00849 30 217 1.9E-14 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS27330 f4929117cf3285300d50881b6bf7f9f4 446 Gene3D G3DSA:1.20.1250.20 24 218 2.0E-33 T 28-03-2018 CU254_RS27330 f4929117cf3285300d50881b6bf7f9f4 446 Gene3D G3DSA:1.20.1250.20 234 445 1.1E-29 T 28-03-2018 CU254_RS27330 f4929117cf3285300d50881b6bf7f9f4 446 ProSitePatterns PS00217 Sugar transport proteins signature 2. 123 148 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CU254_RS27330 f4929117cf3285300d50881b6bf7f9f4 446 SUPERFAMILY SSF103473 13 439 1.44E-81 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS27330 f4929117cf3285300d50881b6bf7f9f4 446 ProSitePatterns PS00216 Sugar transport proteins signature 1. 309 325 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CU254_RS27330 f4929117cf3285300d50881b6bf7f9f4 446 Pfam PF00083 Sugar (and other) transporter 59 440 9.6E-65 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CU254_RS12805 c88c5b649ed2949b04ab61558c7d154f 511 PIRSF PIRSF002741 3 510 3.9E-60 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CU254_RS12805 c88c5b649ed2949b04ab61558c7d154f 511 Gene3D G3DSA:3.10.105.10 298 482 7.1E-37 T 28-03-2018 CU254_RS12805 c88c5b649ed2949b04ab61558c7d154f 511 Gene3D G3DSA:3.90.76.10 46 180 5.6E-20 T 28-03-2018 CU254_RS12805 c88c5b649ed2949b04ab61558c7d154f 511 Gene3D G3DSA:3.40.190.10 181 297 3.1E-21 T 28-03-2018 CU254_RS12805 c88c5b649ed2949b04ab61558c7d154f 511 SUPERFAMILY SSF53850 32 498 6.39E-86 T 28-03-2018 CU254_RS12805 c88c5b649ed2949b04ab61558c7d154f 511 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 80 419 3.4E-58 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CU254_RS09335 19f08b9429a51c65113bcd5b1fc4329e 263 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 14 255 32.617 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CU254_RS09335 19f08b9429a51c65113bcd5b1fc4329e 263 Gene3D G3DSA:3.20.20.70 2 262 4.5E-75 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS09335 19f08b9429a51c65113bcd5b1fc4329e 263 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 8 243 1.6E-64 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CU254_RS09335 19f08b9429a51c65113bcd5b1fc4329e 263 Pfam PF00290 Tryptophan synthase alpha chain 8 254 4.8E-72 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CU254_RS09335 19f08b9429a51c65113bcd5b1fc4329e 263 SUPERFAMILY SSF51366 3 256 1.7E-78 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CU254_RS09335 19f08b9429a51c65113bcd5b1fc4329e 263 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 48 61 - T 28-03-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CU254_RS09850 16d1a1348fc365276f89ac5797d01d9e 378 SUPERFAMILY SSF55874 256 377 3.31E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS09850 16d1a1348fc365276f89ac5797d01d9e 378 Gene3D G3DSA:3.30.565.10 250 378 6.5E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS09850 16d1a1348fc365276f89ac5797d01d9e 378 Pfam PF07730 Histidine kinase 185 252 1.2E-14 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CU254_RS06115 e56f91475989a89915f65264be1d58a6 659 Pfam PF00082 Subtilase family 337 573 6.8E-10 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS06115 e56f91475989a89915f65264be1d58a6 659 Pfam PF09286 Pro-kumamolisin, activation domain 45 180 9.7E-30 T 28-03-2018 IPR015366 Peptidase S53, activation domain GO:0008236 Reactome: R-HSA-381038 CU254_RS06115 e56f91475989a89915f65264be1d58a6 659 SMART SM00944 41 181 9.4E-43 T 28-03-2018 IPR015366 Peptidase S53, activation domain GO:0008236 Reactome: R-HSA-381038 CU254_RS06115 e56f91475989a89915f65264be1d58a6 659 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 556 566 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CU254_RS06115 e56f91475989a89915f65264be1d58a6 659 Gene3D G3DSA:3.40.50.200 244 659 1.6E-32 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS06115 e56f91475989a89915f65264be1d58a6 659 SUPERFAMILY SSF52743 256 656 2.36E-49 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS06115 e56f91475989a89915f65264be1d58a6 659 SUPERFAMILY SSF54897 30 182 2.72E-37 T 28-03-2018 IPR009020 Protease propeptides/proteinase inhibitor I9 CU254_RS23585 3200839d3e3a3c593681d10255916118 276 Gene3D G3DSA:3.30.70.20 151 272 1.1E-19 T 28-03-2018 CU254_RS23585 3200839d3e3a3c593681d10255916118 276 Gene3D G3DSA:3.30.70.20 115 150 6.3E-18 T 28-03-2018 CU254_RS23585 3200839d3e3a3c593681d10255916118 276 Gene3D G3DSA:3.30.70.20 9 114 9.3E-34 T 28-03-2018 CU254_RS23585 3200839d3e3a3c593681d10255916118 276 PIRSF PIRSF036298 4 274 2.8E-63 T 28-03-2018 IPR014603 Formate dehydrogenase iron-sulphur subunit GO:0015944|GO:0045333|GO:0051539 CU254_RS23585 3200839d3e3a3c593681d10255916118 276 SUPERFAMILY SSF54862 8 242 2.72E-59 T 28-03-2018 CU254_RS23585 3200839d3e3a3c593681d10255916118 276 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 131 142 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CU254_RS23585 3200839d3e3a3c593681d10255916118 276 Pfam PF13247 4Fe-4S dicluster domain 90 186 1.2E-23 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CU254_RS10860 eb894d00d85fb07339d6f5adf5a0db9f 275 SUPERFAMILY SSF56655 13 267 6.15E-67 T 28-03-2018 CU254_RS10860 eb894d00d85fb07339d6f5adf5a0db9f 275 Gene3D G3DSA:3.30.540.10 9 161 4.8E-42 T 28-03-2018 CU254_RS10860 eb894d00d85fb07339d6f5adf5a0db9f 275 Pfam PF00459 Inositol monophosphatase family 17 262 3.5E-54 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CU254_RS10860 eb894d00d85fb07339d6f5adf5a0db9f 275 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 222 236 - T 28-03-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 CU254_RS10860 eb894d00d85fb07339d6f5adf5a0db9f 275 Gene3D G3DSA:3.40.190.80 162 275 1.2E-26 T 28-03-2018 CU254_RS10860 eb894d00d85fb07339d6f5adf5a0db9f 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 52 72 1.5E-38 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CU254_RS10860 eb894d00d85fb07339d6f5adf5a0db9f 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 93 109 1.5E-38 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CU254_RS10860 eb894d00d85fb07339d6f5adf5a0db9f 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 219 243 1.5E-38 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CU254_RS10860 eb894d00d85fb07339d6f5adf5a0db9f 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 142 165 1.5E-38 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CU254_RS10860 eb894d00d85fb07339d6f5adf5a0db9f 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 188 209 1.5E-38 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CU254_RS10860 eb894d00d85fb07339d6f5adf5a0db9f 275 PRINTS PR00377 Inositol monophosphatase superfamily signature 74 90 1.5E-38 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CU254_RS10860 eb894d00d85fb07339d6f5adf5a0db9f 275 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 93 106 - T 28-03-2018 IPR020583 Inositol monophosphatase, metal-binding site CU254_RS01425 3a0f9588320b0f7bf6d3188a3fece1a2 345 Pfam PF00348 Polyprenyl synthetase 56 296 5.7E-58 T 28-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 CU254_RS01425 3a0f9588320b0f7bf6d3188a3fece1a2 345 Gene3D G3DSA:1.10.600.10 19 345 7.0E-95 T 28-03-2018 IPR008949 Isoprenoid synthase domain CU254_RS01425 3a0f9588320b0f7bf6d3188a3fece1a2 345 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 226 238 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site CU254_RS01425 3a0f9588320b0f7bf6d3188a3fece1a2 345 SUPERFAMILY SSF48576 31 344 4.96E-83 T 28-03-2018 IPR008949 Isoprenoid synthase domain CU254_RS28830 fd4003116e4e09fcc47b90eefc363d4b 689 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS28830 fd4003116e4e09fcc47b90eefc363d4b 689 SUPERFAMILY SSF52540 35 316 8.75E-66 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS28830 fd4003116e4e09fcc47b90eefc363d4b 689 SUPERFAMILY SSF52540 378 613 3.04E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS28830 fd4003116e4e09fcc47b90eefc363d4b 689 ProSitePatterns PS00211 ABC transporters family signature. 514 528 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS28830 fd4003116e4e09fcc47b90eefc363d4b 689 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 236 301 5.6E-18 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CU254_RS28830 fd4003116e4e09fcc47b90eefc363d4b 689 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 593 656 1.4E-14 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CU254_RS28830 fd4003116e4e09fcc47b90eefc363d4b 689 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 591 688 2.6E-19 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CU254_RS28830 fd4003116e4e09fcc47b90eefc363d4b 689 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 235 324 1.3E-20 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CU254_RS28830 fd4003116e4e09fcc47b90eefc363d4b 689 Pfam PF00005 ABC transporter 391 541 4.0E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS28830 fd4003116e4e09fcc47b90eefc363d4b 689 Pfam PF00005 ABC transporter 28 184 2.1E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS28830 fd4003116e4e09fcc47b90eefc363d4b 689 SMART SM00382 398 599 1.3E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS28830 fd4003116e4e09fcc47b90eefc363d4b 689 SMART SM00382 36 234 1.5E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS28830 fd4003116e4e09fcc47b90eefc363d4b 689 Gene3D G3DSA:3.40.50.300 4 336 9.1E-73 T 28-03-2018 CU254_RS28830 fd4003116e4e09fcc47b90eefc363d4b 689 Gene3D G3DSA:3.40.50.300 358 688 5.9E-74 T 28-03-2018 CU254_RS32740 6ef03d0aa343dfbc1c1d3afe613cdf02 360 Gene3D G3DSA:1.10.150.300 110 198 4.2E-25 T 28-03-2018 IPR023192 TGS-like domain Reactome: R-HSA-114608 CU254_RS32740 6ef03d0aa343dfbc1c1d3afe613cdf02 360 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 9.5E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CU254_RS32740 6ef03d0aa343dfbc1c1d3afe613cdf02 360 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 9.5E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CU254_RS32740 6ef03d0aa343dfbc1c1d3afe613cdf02 360 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 9.5E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CU254_RS32740 6ef03d0aa343dfbc1c1d3afe613cdf02 360 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 9.5E-34 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CU254_RS32740 6ef03d0aa343dfbc1c1d3afe613cdf02 360 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 360 43.598 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 CU254_RS32740 6ef03d0aa343dfbc1c1d3afe613cdf02 360 PIRSF PIRSF006641 1 360 2.0E-139 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 CU254_RS32740 6ef03d0aa343dfbc1c1d3afe613cdf02 360 SUPERFAMILY SSF52540 3 298 1.58E-72 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS32740 6ef03d0aa343dfbc1c1d3afe613cdf02 360 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 3 360 2.9E-129 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 CU254_RS32740 6ef03d0aa343dfbc1c1d3afe613cdf02 360 Gene3D G3DSA:3.10.20.30 260 359 4.7E-44 T 28-03-2018 IPR012675 Beta-grasp domain CU254_RS32740 6ef03d0aa343dfbc1c1d3afe613cdf02 360 Gene3D G3DSA:3.40.50.300 2 80 2.6E-8 T 28-03-2018 CU254_RS32740 6ef03d0aa343dfbc1c1d3afe613cdf02 360 SUPERFAMILY SSF81271 276 360 4.58E-35 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CU254_RS32740 6ef03d0aa343dfbc1c1d3afe613cdf02 360 Pfam PF01926 50S ribosome-binding GTPase 5 128 2.9E-21 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CU254_RS32740 6ef03d0aa343dfbc1c1d3afe613cdf02 360 Pfam PF06071 Protein of unknown function (DUF933) 276 359 4.8E-39 T 28-03-2018 IPR013029 Domain of unknown function DUF933 Reactome: R-HSA-114608 CU254_RS31840 d6730c4f2ee801297f57ffc3613530b8 326 Gene3D G3DSA:1.20.1170.10 123 299 1.2E-4 T 28-03-2018 CU254_RS31840 d6730c4f2ee801297f57ffc3613530b8 326 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 26 46 3.3E-9 T 28-03-2018 IPR005693 Virulence factor Mce protein CU254_RS31840 d6730c4f2ee801297f57ffc3613530b8 326 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 175 193 3.3E-9 T 28-03-2018 IPR005693 Virulence factor Mce protein CU254_RS31840 d6730c4f2ee801297f57ffc3613530b8 326 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 244 263 3.3E-9 T 28-03-2018 IPR005693 Virulence factor Mce protein CU254_RS31840 d6730c4f2ee801297f57ffc3613530b8 326 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 88 104 3.3E-9 T 28-03-2018 IPR005693 Virulence factor Mce protein CU254_RS31840 d6730c4f2ee801297f57ffc3613530b8 326 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 126 150 3.3E-9 T 28-03-2018 IPR005693 Virulence factor Mce protein CU254_RS31840 d6730c4f2ee801297f57ffc3613530b8 326 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 10 287 9.7E-57 T 28-03-2018 IPR005693 Virulence factor Mce protein CU254_RS31840 d6730c4f2ee801297f57ffc3613530b8 326 Pfam PF02470 MlaD protein 37 110 6.3E-15 T 28-03-2018 IPR003399 Mce/MlaD CU254_RS31470 c1816ecece70b712bf5e2667246e33ae 109 SMART SM00450 5 104 3.0E-12 T 28-03-2018 IPR001763 Rhodanese-like domain CU254_RS31470 c1816ecece70b712bf5e2667246e33ae 109 SUPERFAMILY SSF52821 1 108 1.44E-25 T 28-03-2018 IPR001763 Rhodanese-like domain CU254_RS31470 c1816ecece70b712bf5e2667246e33ae 109 ProSitePatterns PS00380 Rhodanese signature 1. 30 41 - T 28-03-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 CU254_RS31470 c1816ecece70b712bf5e2667246e33ae 109 Pfam PF00581 Rhodanese-like domain 7 100 2.0E-11 T 28-03-2018 IPR001763 Rhodanese-like domain CU254_RS31470 c1816ecece70b712bf5e2667246e33ae 109 Gene3D G3DSA:3.40.250.10 1 109 3.6E-22 T 28-03-2018 IPR001763 Rhodanese-like domain CU254_RS21520 505edd70ec058e77c8235188cc4dbdc9 344 Gene3D G3DSA:3.40.50.720 165 312 5.4E-23 T 28-03-2018 CU254_RS21520 505edd70ec058e77c8235188cc4dbdc9 344 SUPERFAMILY SSF51735 143 310 5.64E-30 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS21520 505edd70ec058e77c8235188cc4dbdc9 344 SUPERFAMILY SSF50129 2 174 1.28E-48 T 28-03-2018 IPR011032 GroES-like CU254_RS21520 505edd70ec058e77c8235188cc4dbdc9 344 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 137 1.2E-29 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CU254_RS21520 505edd70ec058e77c8235188cc4dbdc9 344 Gene3D G3DSA:3.90.180.10 1 164 3.8E-48 T 28-03-2018 CU254_RS21520 505edd70ec058e77c8235188cc4dbdc9 344 Pfam PF00107 Zinc-binding dehydrogenase 180 303 4.7E-17 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CU254_RS21520 505edd70ec058e77c8235188cc4dbdc9 344 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 63 77 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CU254_RS31845 76ae4ff8af71dee7e180ee9f56a6de97 276 Gene3D G3DSA:3.40.50.150 85 268 1.5E-14 T 28-03-2018 CU254_RS31845 76ae4ff8af71dee7e180ee9f56a6de97 276 Pfam PF13578 Methyltransferase domain 115 226 6.8E-11 T 28-03-2018 CU254_RS31845 76ae4ff8af71dee7e180ee9f56a6de97 276 SUPERFAMILY SSF53335 52 245 2.78E-15 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS09300 2577841e7b98c864d6b2295143bf4f1c 119 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 7 110 31.498 T 28-03-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 CU254_RS09300 2577841e7b98c864d6b2295143bf4f1c 119 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 56 108 8.0E-19 T 28-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 CU254_RS09300 2577841e7b98c864d6b2295143bf4f1c 119 SUPERFAMILY SSF141734 8 108 1.31E-47 T 28-03-2018 CU254_RS09300 2577841e7b98c864d6b2295143bf4f1c 119 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 33 105 2.5E-36 T 28-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 CU254_RS01215 10c7b78b3911944b95951b4a10850b46 193 Pfam PF00578 AhpC/TSA family 51 171 7.3E-19 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CU254_RS01215 10c7b78b3911944b95951b4a10850b46 193 Gene3D G3DSA:3.40.30.10 39 192 5.4E-26 T 28-03-2018 CU254_RS01215 10c7b78b3911944b95951b4a10850b46 193 SUPERFAMILY SSF52833 47 191 3.98E-26 T 28-03-2018 IPR012336 Thioredoxin-like fold CU254_RS01215 10c7b78b3911944b95951b4a10850b46 193 ProSitePatterns PS00194 Thioredoxin family active site. 79 97 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CU254_RS03615 5907b91f46c8d2f2fe95079bce3215e5 465 Gene3D G3DSA:3.40.30.20 419 464 9.3E-4 T 28-03-2018 CU254_RS03615 5907b91f46c8d2f2fe95079bce3215e5 465 Pfam PF01494 FAD binding domain 2 332 6.5E-79 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CU254_RS03615 5907b91f46c8d2f2fe95079bce3215e5 465 SUPERFAMILY SSF51905 261 340 7.98E-65 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS03615 5907b91f46c8d2f2fe95079bce3215e5 465 SUPERFAMILY SSF51905 2 171 7.98E-65 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS03615 5907b91f46c8d2f2fe95079bce3215e5 465 Gene3D G3DSA:3.50.50.60 1 364 1.2E-62 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS03615 5907b91f46c8d2f2fe95079bce3215e5 465 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 2.4E-35 T 28-03-2018 CU254_RS03615 5907b91f46c8d2f2fe95079bce3215e5 465 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 150 165 2.4E-35 T 28-03-2018 CU254_RS03615 5907b91f46c8d2f2fe95079bce3215e5 465 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 289 305 2.4E-35 T 28-03-2018 CU254_RS03615 5907b91f46c8d2f2fe95079bce3215e5 465 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 274 289 2.4E-35 T 28-03-2018 CU254_RS40110 022c71b8a88f2aa87da374e1495ad59b 311 SUPERFAMILY SSF52540 7 310 5.49E-70 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS40110 022c71b8a88f2aa87da374e1495ad59b 311 Gene3D G3DSA:3.40.50.300 8 310 4.0E-55 T 28-03-2018 CU254_RS40110 022c71b8a88f2aa87da374e1495ad59b 311 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 91 228 6.8E-14 T 28-03-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 Reactome: R-HSA-73614 CU254_RS40110 022c71b8a88f2aa87da374e1495ad59b 311 Hamap MF_00215 Pantothenate kinase [coaA]. 1 311 175.093 T 28-03-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CU254_RS40110 022c71b8a88f2aa87da374e1495ad59b 311 PIRSF PIRSF000545 2 311 8.9E-141 T 28-03-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CU254_RS40110 022c71b8a88f2aa87da374e1495ad59b 311 TIGRFAM TIGR00554 panK_bact: pantothenate kinase 10 310 3.8E-122 T 28-03-2018 IPR004566 Pantothenate kinase GO:0004594|GO:0005524|GO:0005737|GO:0015937 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CU254_RS17950 91054da3d1e551292786efdae004ad4b 156 Pfam PF04075 F420H(2)-dependent quinone reductase 44 154 9.1E-30 T 28-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CU254_RS17950 91054da3d1e551292786efdae004ad4b 156 Gene3D G3DSA:2.30.110.10 19 156 1.9E-37 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS17950 91054da3d1e551292786efdae004ad4b 156 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 45 154 9.5E-30 T 28-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CU254_RS17950 91054da3d1e551292786efdae004ad4b 156 SUPERFAMILY SSF50475 49 155 6.62E-9 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS34415 fa5258efe0158afe62800ef7d2ea2d4f 313 SUPERFAMILY SSF56281 7 290 3.25E-59 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS34415 fa5258efe0158afe62800ef7d2ea2d4f 313 Pfam PF00753 Metallo-beta-lactamase superfamily 31 225 5.3E-21 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS34415 fa5258efe0158afe62800ef7d2ea2d4f 313 SMART SM00849 30 225 2.7E-23 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS34415 fa5258efe0158afe62800ef7d2ea2d4f 313 Gene3D G3DSA:3.60.15.10 3 251 4.1E-33 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS36830 7b805045e9034c1849997ce0ec5fad04 372 SUPERFAMILY SSF52540 230 292 1.86E-32 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS36830 7b805045e9034c1849997ce0ec5fad04 372 SUPERFAMILY SSF52540 18 188 1.86E-32 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS36830 7b805045e9034c1849997ce0ec5fad04 372 Pfam PF02374 Anion-transporting ATPase 19 291 5.9E-26 T 28-03-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 CU254_RS36830 7b805045e9034c1849997ce0ec5fad04 372 Gene3D G3DSA:3.40.50.300 1 372 1.8E-99 T 28-03-2018 CU254_RS20165 70871816438cd650b1fd952afc0d7e6f 161 SUPERFAMILY SSF55729 2 146 1.05E-24 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS20165 70871816438cd650b1fd952afc0d7e6f 161 PIRSF PIRSF037663 5 161 8.5E-54 T 28-03-2018 IPR017255 Acetyltransferase, GNAT, predicted CU254_RS20165 70871816438cd650b1fd952afc0d7e6f 161 Pfam PF00583 Acetyltransferase (GNAT) family 51 136 4.2E-15 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS20165 70871816438cd650b1fd952afc0d7e6f 161 Gene3D G3DSA:3.40.630.30 4 160 6.6E-28 T 28-03-2018 CU254_RS02670 b178671fd6ee2d019c59383136318b6c 103 Pfam PF11222 Protein of unknown function (DUF3017) 21 93 1.0E-21 T 28-03-2018 IPR021385 Protein of unknown function DUF3017 CU254_RS16710 b5764a8875d88e4cf204f27a51ee65f0 335 Gene3D G3DSA:1.10.260.40 1 55 1.3E-15 T 28-03-2018 CU254_RS16710 b5764a8875d88e4cf204f27a51ee65f0 335 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 47 8.5E-13 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CU254_RS16710 b5764a8875d88e4cf204f27a51ee65f0 335 SUPERFAMILY SSF53822 59 331 1.33E-68 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CU254_RS16710 b5764a8875d88e4cf204f27a51ee65f0 335 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 28-03-2018 CU254_RS16710 b5764a8875d88e4cf204f27a51ee65f0 335 SUPERFAMILY SSF47413 4 49 3.92E-11 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS16710 b5764a8875d88e4cf204f27a51ee65f0 335 SMART SM00354 2 69 2.8E-18 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CU254_RS16710 b5764a8875d88e4cf204f27a51ee65f0 335 Gene3D G3DSA:3.40.50.2300 184 335 1.0E-43 T 28-03-2018 CU254_RS16710 b5764a8875d88e4cf204f27a51ee65f0 335 Pfam PF13377 Periplasmic binding protein-like domain 171 330 1.6E-39 T 28-03-2018 CU254_RS16710 b5764a8875d88e4cf204f27a51ee65f0 335 Gene3D G3DSA:3.40.50.2300 56 183 1.1E-25 T 28-03-2018 CU254_RS16935 e8663b62399816db8ae3b7c6f5cbe454 321 Gene3D G3DSA:3.40.630.10 36 317 5.2E-63 T 28-03-2018 CU254_RS16935 e8663b62399816db8ae3b7c6f5cbe454 321 SUPERFAMILY SSF53187 46 311 4.65E-64 T 28-03-2018 CU254_RS16935 e8663b62399816db8ae3b7c6f5cbe454 321 Pfam PF04389 Peptidase family M28 101 305 2.6E-45 T 28-03-2018 IPR007484 Peptidase M28 CU254_RS15885 7208059a8bd1c1b29b687a2ab8cb5e43 486 Gene3D G3DSA:3.90.550.10 1 229 1.5E-30 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS15885 7208059a8bd1c1b29b687a2ab8cb5e43 486 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 407 452 3.6E-9 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CU254_RS15885 7208059a8bd1c1b29b687a2ab8cb5e43 486 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 315 453 6.3E-34 T 28-03-2018 IPR006543 Histidinol-phosphate phosphatase GO:0016791 CU254_RS15885 7208059a8bd1c1b29b687a2ab8cb5e43 486 SUPERFAMILY SSF53448 4 221 2.4E-33 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS15885 7208059a8bd1c1b29b687a2ab8cb5e43 486 Pfam PF13242 HAD-hyrolase-like 407 478 3.0E-13 T 28-03-2018 CU254_RS15885 7208059a8bd1c1b29b687a2ab8cb5e43 486 Pfam PF00535 Glycosyl transferase family 2 8 113 2.3E-14 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CU254_RS15885 7208059a8bd1c1b29b687a2ab8cb5e43 486 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 316 454 6.0E-31 T 28-03-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 CU254_RS15885 7208059a8bd1c1b29b687a2ab8cb5e43 486 Gene3D G3DSA:3.40.50.1000 315 482 7.2E-30 T 28-03-2018 IPR023214 HAD-like domain CU254_RS15885 7208059a8bd1c1b29b687a2ab8cb5e43 486 SUPERFAMILY SSF56784 313 478 2.45E-41 T 28-03-2018 IPR023214 HAD-like domain CU254_RS06470 a0639b2a0ff343174ce6eb338bbda77a 319 SUPERFAMILY SSF48452 187 273 9.62E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS06470 a0639b2a0ff343174ce6eb338bbda77a 319 Gene3D G3DSA:3.40.30.10 48 241 6.8E-36 T 28-03-2018 CU254_RS06470 a0639b2a0ff343174ce6eb338bbda77a 319 SUPERFAMILY SSF52833 52 162 8.62E-25 T 28-03-2018 IPR012336 Thioredoxin-like fold CU254_RS06470 a0639b2a0ff343174ce6eb338bbda77a 319 Pfam PF14561 Tetratricopeptide repeat 239 319 4.9E-20 T 28-03-2018 CU254_RS06470 a0639b2a0ff343174ce6eb338bbda77a 319 Pfam PF00085 Thioredoxin 56 156 1.1E-14 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 CU254_RS06470 a0639b2a0ff343174ce6eb338bbda77a 319 Gene3D G3DSA:1.25.40.10 242 319 0.059 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS22495 1f1bac39fc9d156a60b2b775c171df96 125 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS22495 1f1bac39fc9d156a60b2b775c171df96 125 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 2 114 1.2E-42 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS22495 1f1bac39fc9d156a60b2b775c171df96 125 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 28.024 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS22495 1f1bac39fc9d156a60b2b775c171df96 125 SUPERFAMILY SSF74731 3 115 5.36E-44 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS22495 1f1bac39fc9d156a60b2b775c171df96 125 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 21 70 1.0E-20 T 28-03-2018 CU254_RS22495 1f1bac39fc9d156a60b2b775c171df96 125 Pfam PF00453 Ribosomal protein L20 3 109 1.4E-43 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS22495 1f1bac39fc9d156a60b2b775c171df96 125 Gene3D G3DSA:1.10.1900.20 56 116 2.7E-26 T 28-03-2018 IPR035566 Ribosomal protein L20 C-terminal domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS22495 1f1bac39fc9d156a60b2b775c171df96 125 PRINTS PR00062 Ribosomal protein L20 signature 42 71 3.5E-38 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS22495 1f1bac39fc9d156a60b2b775c171df96 125 PRINTS PR00062 Ribosomal protein L20 signature 12 41 3.5E-38 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS22495 1f1bac39fc9d156a60b2b775c171df96 125 PRINTS PR00062 Ribosomal protein L20 signature 75 101 3.5E-38 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS29610 80a8b98161fd07bab2428008523efe98 286 Gene3D G3DSA:1.10.3470.10 1 278 3.3E-31 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CU254_RS29610 80a8b98161fd07bab2428008523efe98 286 Pfam PF02653 Branched-chain amino acid transport system / permease component 6 271 1.7E-22 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CU254_RS15270 59e46fd8347c80baf680b6c7a6e4d525 213 SUPERFAMILY SSF46689 4 82 9.23E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS15270 59e46fd8347c80baf680b6c7a6e4d525 213 Gene3D G3DSA:1.10.10.60 2 38 1.9E-13 T 28-03-2018 CU254_RS15270 59e46fd8347c80baf680b6c7a6e4d525 213 SUPERFAMILY SSF48498 90 182 7.79E-12 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS15270 59e46fd8347c80baf680b6c7a6e4d525 213 ProSitePatterns PS01081 TetR-type HTH domain signature. 29 59 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CU254_RS15270 59e46fd8347c80baf680b6c7a6e4d525 213 Gene3D G3DSA:1.10.260.40 39 70 2.6E-10 T 28-03-2018 CU254_RS15270 59e46fd8347c80baf680b6c7a6e4d525 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 1.5E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS15270 59e46fd8347c80baf680b6c7a6e4d525 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 1.5E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS15270 59e46fd8347c80baf680b6c7a6e4d525 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 61 3.0E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS15270 59e46fd8347c80baf680b6c7a6e4d525 213 Gene3D G3DSA:1.10.357.10 71 211 8.9E-15 T 28-03-2018 CU254_RS15270 59e46fd8347c80baf680b6c7a6e4d525 213 Pfam PF16859 Bacterial transcriptional repressor C-terminal 87 175 1.2E-9 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS25105 b8608d478f99da4cb9f0642801e83efb 247 Pfam PF00106 short chain dehydrogenase 4 193 1.7E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS25105 b8608d478f99da4cb9f0642801e83efb 247 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS25105 b8608d478f99da4cb9f0642801e83efb 247 Gene3D G3DSA:3.40.50.720 2 247 6.9E-36 T 28-03-2018 CU254_RS25105 b8608d478f99da4cb9f0642801e83efb 247 SUPERFAMILY SSF51735 3 245 2.03E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS25105 b8608d478f99da4cb9f0642801e83efb 247 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 182 7.8E-5 T 28-03-2018 CU254_RS25105 b8608d478f99da4cb9f0642801e83efb 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.1E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS25105 b8608d478f99da4cb9f0642801e83efb 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.1E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS25105 b8608d478f99da4cb9f0642801e83efb 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.1E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS25105 b8608d478f99da4cb9f0642801e83efb 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.1E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS25105 b8608d478f99da4cb9f0642801e83efb 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.1E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23565 47c247e2b2956f05ace992f98aff7fb9 185 Pfam PF01814 Hemerythrin HHE cation binding domain 4 117 1.8E-12 T 28-03-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 CU254_RS23565 47c247e2b2956f05ace992f98aff7fb9 185 Gene3D G3DSA:1.20.120.520 6 143 2.8E-17 T 28-03-2018 CU254_RS23565 47c247e2b2956f05ace992f98aff7fb9 185 TIGRFAM TIGR04537 encap_target: encapsulation C-terminal sorting signal 175 184 0.077 T 28-03-2018 CU254_RS19795 d3665ce5cae5cfb00ab7f207d67def00 153 Gene3D G3DSA:3.10.450.50 13 151 2.1E-59 T 28-03-2018 CU254_RS19795 d3665ce5cae5cfb00ab7f207d67def00 153 SUPERFAMILY SSF54427 3 145 1.37E-67 T 28-03-2018 IPR032710 NTF2-like domain CU254_RS19795 d3665ce5cae5cfb00ab7f207d67def00 153 Pfam PF07080 Protein of unknown function (DUF1348) 9 137 1.0E-60 T 28-03-2018 IPR009783 Protein of unknown function DUF1348 CU254_RS16600 249b869d675c31c7380a044cbedcad16 495 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 290 386 5.1E-33 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CU254_RS16600 249b869d675c31c7380a044cbedcad16 495 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 49 266 1.4E-64 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CU254_RS16600 249b869d675c31c7380a044cbedcad16 495 SMART SM00079 48 267 5.4E-4 T 28-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 CU254_RS16600 249b869d675c31c7380a044cbedcad16 495 SMART SM00062 48 268 4.3E-66 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CU254_RS16600 249b869d675c31c7380a044cbedcad16 495 Gene3D G3DSA:1.10.3720.10 287 493 3.9E-39 T 28-03-2018 CU254_RS16600 249b869d675c31c7380a044cbedcad16 495 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 316 491 6.3E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS16600 249b869d675c31c7380a044cbedcad16 495 SUPERFAMILY SSF53850 15 267 6.8E-67 T 28-03-2018 CU254_RS16600 249b869d675c31c7380a044cbedcad16 495 SUPERFAMILY SSF161098 290 477 1.57E-47 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS16600 249b869d675c31c7380a044cbedcad16 495 Gene3D G3DSA:3.40.190.10 45 169 4.5E-35 T 28-03-2018 CU254_RS16600 249b869d675c31c7380a044cbedcad16 495 Gene3D G3DSA:3.40.190.10 170 277 1.5E-15 T 28-03-2018 CU254_RS16600 249b869d675c31c7380a044cbedcad16 495 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 71 84 - T 28-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 CU254_RS08225 25d3dcb63d910cad3037de6656b6bba6 420 Gene3D G3DSA:3.50.50.60 8 420 2.3E-46 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS08225 25d3dcb63d910cad3037de6656b6bba6 420 Pfam PF01266 FAD dependent oxidoreductase 15 402 4.9E-62 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CU254_RS08225 25d3dcb63d910cad3037de6656b6bba6 420 SUPERFAMILY SSF51905 161 278 2.98E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS08225 25d3dcb63d910cad3037de6656b6bba6 420 SUPERFAMILY SSF51905 365 420 2.98E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS08225 25d3dcb63d910cad3037de6656b6bba6 420 SUPERFAMILY SSF51905 14 99 2.98E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS08225 25d3dcb63d910cad3037de6656b6bba6 420 SUPERFAMILY SSF54373 278 363 1.44E-10 T 28-03-2018 CU254_RS10580 bc31800c358cfee5a3258f581703b325 509 Gene3D G3DSA:3.30.300.30 405 509 3.3E-28 T 28-03-2018 CU254_RS10580 bc31800c358cfee5a3258f581703b325 509 Pfam PF00501 AMP-binding enzyme 7 410 1.5E-77 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS10580 bc31800c358cfee5a3258f581703b325 509 SUPERFAMILY SSF56801 7 508 3.01E-127 T 28-03-2018 CU254_RS10580 bc31800c358cfee5a3258f581703b325 509 Gene3D G3DSA:2.30.38.10 321 403 3.5E-16 T 28-03-2018 CU254_RS10580 bc31800c358cfee5a3258f581703b325 509 Gene3D G3DSA:3.40.50.980 165 320 7.1E-39 T 28-03-2018 CU254_RS10580 bc31800c358cfee5a3258f581703b325 509 Pfam PF13193 AMP-binding enzyme C-terminal domain 419 497 1.6E-17 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS10580 bc31800c358cfee5a3258f581703b325 509 Gene3D G3DSA:3.40.50.980 5 164 2.4E-32 T 28-03-2018 CU254_RS10580 bc31800c358cfee5a3258f581703b325 509 ProSitePatterns PS00455 Putative AMP-binding domain signature. 158 169 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS06630 d3e91476e34d80e125b8ce2ffb0c0bf9 251 Gene3D G3DSA:2.160.10.10 53 114 0.0024 T 28-03-2018 CU254_RS06630 d3e91476e34d80e125b8ce2ffb0c0bf9 251 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 166 200 2.8E-6 T 28-03-2018 IPR001451 Hexapeptide repeat CU254_RS06630 d3e91476e34d80e125b8ce2ffb0c0bf9 251 Gene3D G3DSA:2.160.10.10 115 250 5.0E-30 T 28-03-2018 CU254_RS06630 d3e91476e34d80e125b8ce2ffb0c0bf9 251 SUPERFAMILY SSF51161 36 224 1.3E-32 T 28-03-2018 IPR011004 Trimeric LpxA-like CU254_RS05925 422a4288552161abbaf420db6997e905 535 Gene3D G3DSA:2.160.20.10 3 174 0.019 T 28-03-2018 IPR012334 Pectin lyase fold CU254_RS05925 422a4288552161abbaf420db6997e905 535 SUPERFAMILY SSF51126 248 309 3.14E-7 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor CU254_RS05925 422a4288552161abbaf420db6997e905 535 SUPERFAMILY SSF51126 357 435 3.14E-7 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor CU254_RS05925 422a4288552161abbaf420db6997e905 535 Gene3D G3DSA:2.160.20.10 242 481 7.3E-31 T 28-03-2018 IPR012334 Pectin lyase fold CU254_RS15795 77f3ad68f6fea3277693ac3101779983 794 SUPERFAMILY SSF50692 621 771 4.29E-36 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain CU254_RS15795 77f3ad68f6fea3277693ac3101779983 794 Pfam PF01568 Molydopterin dinucleotide binding domain 649 765 2.6E-26 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CU254_RS15795 77f3ad68f6fea3277693ac3101779983 794 Pfam PF00384 Molybdopterin oxidoreductase 96 520 7.7E-68 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS15795 77f3ad68f6fea3277693ac3101779983 794 SUPERFAMILY SSF53706 40 596 2.09E-153 T 28-03-2018 CU254_RS15795 77f3ad68f6fea3277693ac3101779983 794 Gene3D G3DSA:2.40.40.20 589 772 3.9E-43 T 28-03-2018 CU254_RS15795 77f3ad68f6fea3277693ac3101779983 794 SMART SM00926 39 92 0.0013 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS15795 77f3ad68f6fea3277693ac3101779983 794 Gene3D G3DSA:3.40.50.740 99 282 1.7E-32 T 28-03-2018 CU254_RS15795 77f3ad68f6fea3277693ac3101779983 794 Gene3D G3DSA:3.40.50.740 289 587 1.8E-69 T 28-03-2018 CU254_RS15795 77f3ad68f6fea3277693ac3101779983 794 Gene3D G3DSA:2.20.25.90 36 95 3.4E-8 T 28-03-2018 CU254_RS10570 91512a6c2162bc850fe987ae0b8d63a1 350 PIRSF PIRSF000429 1 348 2.7E-17 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CU254_RS10570 91512a6c2162bc850fe987ae0b8d63a1 350 SUPERFAMILY SSF53901 24 118 1.27E-15 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS10570 91512a6c2162bc850fe987ae0b8d63a1 350 SUPERFAMILY SSF53901 176 322 1.27E-15 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS10570 91512a6c2162bc850fe987ae0b8d63a1 350 Gene3D G3DSA:3.40.47.10 232 346 2.2E-5 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS10570 91512a6c2162bc850fe987ae0b8d63a1 350 Gene3D G3DSA:3.40.47.10 1 231 2.1E-14 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS30645 8b470e99b2330833849619c09af47267 508 Pfam PF00501 AMP-binding enzyme 13 406 1.4E-83 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS30645 8b470e99b2330833849619c09af47267 508 Gene3D G3DSA:3.40.50.980 3 166 9.1E-38 T 28-03-2018 CU254_RS30645 8b470e99b2330833849619c09af47267 508 SUPERFAMILY SSF56801 6 504 5.63E-132 T 28-03-2018 CU254_RS30645 8b470e99b2330833849619c09af47267 508 Gene3D G3DSA:2.30.38.10 325 399 1.3E-11 T 28-03-2018 CU254_RS30645 8b470e99b2330833849619c09af47267 508 Gene3D G3DSA:3.40.50.980 167 323 2.5E-37 T 28-03-2018 CU254_RS30645 8b470e99b2330833849619c09af47267 508 Gene3D G3DSA:3.30.300.30 401 508 5.4E-32 T 28-03-2018 CU254_RS30645 8b470e99b2330833849619c09af47267 508 Pfam PF13193 AMP-binding enzyme C-terminal domain 415 489 1.1E-25 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS32870 d025433c00c7b9cfaac3f2f65955a247 428 Gene3D G3DSA:3.40.50.1010 1 168 1.7E-29 T 28-03-2018 IPR029060 PIN domain-like CU254_RS32870 d025433c00c7b9cfaac3f2f65955a247 428 SMART SM00670 1 125 4.9E-12 T 28-03-2018 IPR002716 PIN domain CU254_RS32870 d025433c00c7b9cfaac3f2f65955a247 428 Gene3D G3DSA:3.40.50.300 217 422 1.0E-17 T 28-03-2018 CU254_RS32870 d025433c00c7b9cfaac3f2f65955a247 428 SUPERFAMILY SSF88723 90 134 3.01E-8 T 28-03-2018 IPR029060 PIN domain-like CU254_RS32870 d025433c00c7b9cfaac3f2f65955a247 428 SUPERFAMILY SSF88723 1 57 3.01E-8 T 28-03-2018 IPR029060 PIN domain-like CU254_RS32870 d025433c00c7b9cfaac3f2f65955a247 428 SUPERFAMILY SSF52540 218 380 9.91E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS32870 d025433c00c7b9cfaac3f2f65955a247 428 Pfam PF02562 PhoH-like protein 220 424 5.0E-53 T 28-03-2018 IPR003714 PhoH-like protein GO:0005524 CU254_RS32870 d025433c00c7b9cfaac3f2f65955a247 428 Pfam PF13638 PIN domain 1 138 1.1E-27 T 28-03-2018 IPR002716 PIN domain CU254_RS05680 5f040022def84c9c92f25d8570cbb327 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 119 139 1.2E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS05680 5f040022def84c9c92f25d8570cbb327 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 1.2E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS05680 5f040022def84c9c92f25d8570cbb327 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 1.2E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS05680 5f040022def84c9c92f25d8570cbb327 156 PRINTS PR00598 Bacterial regulatory protein MarR family signature 53 69 1.2E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS05680 5f040022def84c9c92f25d8570cbb327 156 Pfam PF12802 MarR family 43 93 2.0E-9 T 28-03-2018 CU254_RS05680 5f040022def84c9c92f25d8570cbb327 156 SUPERFAMILY SSF46785 8 140 1.77E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS05680 5f040022def84c9c92f25d8570cbb327 156 SMART SM00347 30 129 3.4E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS05680 5f040022def84c9c92f25d8570cbb327 156 Gene3D G3DSA:1.10.10.10 3 147 1.3E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS05680 5f040022def84c9c92f25d8570cbb327 156 ProSitePatterns PS01117 MarR-type HTH domain signature. 67 102 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CU254_RS20085 6538ee2289bcb2f4a1065e7690ba27e2 430 Pfam PF01547 Bacterial extracellular solute-binding protein 50 344 7.2E-46 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 CU254_RS20085 6538ee2289bcb2f4a1065e7690ba27e2 430 Gene3D G3DSA:3.40.190.10 169 387 1.0E-36 T 28-03-2018 CU254_RS20085 6538ee2289bcb2f4a1065e7690ba27e2 430 SUPERFAMILY SSF53850 19 428 4.14E-76 T 28-03-2018 CU254_RS20085 6538ee2289bcb2f4a1065e7690ba27e2 430 Gene3D G3DSA:3.40.190.10 40 168 1.5E-26 T 28-03-2018 CU254_RS02180 ce47770a673b9f8a23287fada5198432 107 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 9 92 1.2E-14 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CU254_RS02180 ce47770a673b9f8a23287fada5198432 107 Gene3D G3DSA:1.10.287.1060 2 99 1.4E-16 T 28-03-2018 CU254_RS02180 ce47770a673b9f8a23287fada5198432 107 SUPERFAMILY SSF140453 6 97 3.14E-15 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CU254_RS02180 ce47770a673b9f8a23287fada5198432 107 Pfam PF06013 Proteins of 100 residues with WXG 9 89 4.0E-13 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CU254_RS34675 32b1003b3b1833e42b971b9238b76092 511 Gene3D G3DSA:3.40.50.980 164 313 2.3E-36 T 28-03-2018 CU254_RS34675 32b1003b3b1833e42b971b9238b76092 511 Pfam PF00501 AMP-binding enzyme 15 403 1.6E-93 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS34675 32b1003b3b1833e42b971b9238b76092 511 Pfam PF13193 AMP-binding enzyme C-terminal domain 412 485 5.1E-17 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS34675 32b1003b3b1833e42b971b9238b76092 511 Gene3D G3DSA:3.40.50.980 5 163 1.6E-44 T 28-03-2018 CU254_RS34675 32b1003b3b1833e42b971b9238b76092 511 SUPERFAMILY SSF56801 8 496 6.41E-142 T 28-03-2018 CU254_RS34675 32b1003b3b1833e42b971b9238b76092 511 Gene3D G3DSA:3.30.300.30 397 501 2.2E-25 T 28-03-2018 CU254_RS34675 32b1003b3b1833e42b971b9238b76092 511 Gene3D G3DSA:2.30.38.10 314 396 7.1E-27 T 28-03-2018 CU254_RS34675 32b1003b3b1833e42b971b9238b76092 511 ProSitePatterns PS00455 Putative AMP-binding domain signature. 158 169 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS32955 37f1efb3dfc8d704e0a7ee7c40126048 399 PIRSF PIRSF009283 27 399 6.7E-128 T 28-03-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 CU254_RS32955 37f1efb3dfc8d704e0a7ee7c40126048 399 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 40 150 9.2E-8 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CU254_RS32955 37f1efb3dfc8d704e0a7ee7c40126048 399 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 210 353 5.9E-13 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CU254_RS32955 37f1efb3dfc8d704e0a7ee7c40126048 399 Gene3D G3DSA:3.10.180.10 197 399 1.9E-66 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS32955 37f1efb3dfc8d704e0a7ee7c40126048 399 TIGRFAM TIGR01263 4HPPD: 4-hydroxyphenylpyruvate dioxygenase 39 399 4.9E-127 T 28-03-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 CU254_RS32955 37f1efb3dfc8d704e0a7ee7c40126048 399 SUPERFAMILY SSF54593 30 386 7.77E-89 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS32955 37f1efb3dfc8d704e0a7ee7c40126048 399 Gene3D G3DSA:3.10.180.10 22 194 2.9E-33 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS00080 1e106c8c57a673e830e6b519b9602cd8 282 SUPERFAMILY SSF53335 8 259 2.24E-42 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS00080 1e106c8c57a673e830e6b519b9602cd8 282 Pfam PF04672 S-adenosyl methyltransferase 15 280 2.6E-76 T 28-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CU254_RS00080 1e106c8c57a673e830e6b519b9602cd8 282 PIRSF PIRSF017393 1 280 2.4E-78 T 28-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CU254_RS00080 1e106c8c57a673e830e6b519b9602cd8 282 Gene3D G3DSA:3.40.50.150 1 280 2.1E-40 T 28-03-2018 CU254_RS14005 5451c94696d0276577fd9eaedbf23162 690 SUPERFAMILY SSF81345 13 346 1.57E-59 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CU254_RS14005 5451c94696d0276577fd9eaedbf23162 690 SUPERFAMILY SSF81345 362 685 4.18E-72 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CU254_RS14005 5451c94696d0276577fd9eaedbf23162 690 Pfam PF01032 FecCD transport family 27 346 5.5E-68 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CU254_RS14005 5451c94696d0276577fd9eaedbf23162 690 Pfam PF01032 FecCD transport family 378 685 4.2E-81 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CU254_RS14005 5451c94696d0276577fd9eaedbf23162 690 Gene3D G3DSA:1.10.3470.10 11 353 9.4E-55 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CU254_RS14005 5451c94696d0276577fd9eaedbf23162 690 Gene3D G3DSA:1.10.3470.10 361 690 1.7E-59 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CU254_RS14155 85c5d44ac35c3f7c1ae95ce25c7595fb 217 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 172 184 2.0E-9 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CU254_RS14155 85c5d44ac35c3f7c1ae95ce25c7595fb 217 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 133 143 2.0E-9 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CU254_RS14155 85c5d44ac35c3f7c1ae95ce25c7595fb 217 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 144 155 2.0E-9 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CU254_RS14155 85c5d44ac35c3f7c1ae95ce25c7595fb 217 SUPERFAMILY SSF46785 16 80 4.42E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS14155 85c5d44ac35c3f7c1ae95ce25c7595fb 217 TIGRFAM TIGR00498 lexA: repressor LexA 14 216 4.8E-63 T 28-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 CU254_RS14155 85c5d44ac35c3f7c1ae95ce25c7595fb 217 Gene3D G3DSA:2.10.109.10 102 217 7.6E-24 T 28-03-2018 CU254_RS14155 85c5d44ac35c3f7c1ae95ce25c7595fb 217 Pfam PF00717 Peptidase S24-like 136 200 6.0E-14 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CU254_RS14155 85c5d44ac35c3f7c1ae95ce25c7595fb 217 SUPERFAMILY SSF51306 96 215 4.36E-32 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CU254_RS14155 85c5d44ac35c3f7c1ae95ce25c7595fb 217 Hamap MF_00015 LexA repressor [lexA]. 15 217 30.175 T 28-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 CU254_RS14155 85c5d44ac35c3f7c1ae95ce25c7595fb 217 Pfam PF01726 LexA DNA binding domain 14 76 3.9E-21 T 28-03-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 CU254_RS14155 85c5d44ac35c3f7c1ae95ce25c7595fb 217 Gene3D G3DSA:1.10.10.10 14 80 1.2E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS34600 0625233008d5434789e8fba85b96ea4e 405 Pfam PF00722 Glycosyl hydrolases family 16 79 269 1.8E-40 T 28-03-2018 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 CU254_RS34600 0625233008d5434789e8fba85b96ea4e 405 SMART SM00458 278 404 2.9E-27 T 28-03-2018 IPR000772 Ricin B, lectin domain CU254_RS34600 0625233008d5434789e8fba85b96ea4e 405 SUPERFAMILY SSF49899 28 273 5.6E-72 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CU254_RS34600 0625233008d5434789e8fba85b96ea4e 405 Gene3D G3DSA:2.80.10.50 326 361 3.3E-14 T 28-03-2018 CU254_RS34600 0625233008d5434789e8fba85b96ea4e 405 Gene3D G3DSA:2.60.120.200 35 273 2.5E-71 T 28-03-2018 CU254_RS34600 0625233008d5434789e8fba85b96ea4e 405 SUPERFAMILY SSF50370 278 403 3.06E-38 T 28-03-2018 IPR000772 Ricin B, lectin domain CU254_RS34600 0625233008d5434789e8fba85b96ea4e 405 Gene3D G3DSA:2.80.10.50 278 325 1.6E-9 T 28-03-2018 CU254_RS34600 0625233008d5434789e8fba85b96ea4e 405 Gene3D G3DSA:2.80.10.50 362 405 6.9E-14 T 28-03-2018 CU254_RS34600 0625233008d5434789e8fba85b96ea4e 405 Pfam PF00652 Ricin-type beta-trefoil lectin domain 280 401 2.2E-28 T 28-03-2018 IPR000772 Ricin B, lectin domain CU254_RS22580 2cb86497018c3e9b95c96bbc71b1c720 255 Gene3D G3DSA:3.40.50.720 1 35 1.5E-7 T 28-03-2018 CU254_RS22580 2cb86497018c3e9b95c96bbc71b1c720 255 Gene3D G3DSA:3.40.50.720 36 252 2.5E-60 T 28-03-2018 CU254_RS22580 2cb86497018c3e9b95c96bbc71b1c720 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS22580 2cb86497018c3e9b95c96bbc71b1c720 255 SUPERFAMILY SSF51735 3 249 1.18E-71 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS22580 2cb86497018c3e9b95c96bbc71b1c720 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 6.3E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS22580 2cb86497018c3e9b95c96bbc71b1c720 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 6.3E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS22580 2cb86497018c3e9b95c96bbc71b1c720 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 6.3E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS22580 2cb86497018c3e9b95c96bbc71b1c720 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 4.2E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS22580 2cb86497018c3e9b95c96bbc71b1c720 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 4.2E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS22580 2cb86497018c3e9b95c96bbc71b1c720 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 4.2E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS22580 2cb86497018c3e9b95c96bbc71b1c720 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 4.2E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS22580 2cb86497018c3e9b95c96bbc71b1c720 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 4.2E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS22580 2cb86497018c3e9b95c96bbc71b1c720 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 4.2E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS22580 2cb86497018c3e9b95c96bbc71b1c720 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 247 6.3E-54 T 28-03-2018 CU254_RS03670 89c274f390d58a3f43366f883e57b509 301 SUPERFAMILY SSF53448 28 262 1.55E-55 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS03670 89c274f390d58a3f43366f883e57b509 301 Pfam PF00535 Glycosyl transferase family 2 29 144 4.2E-13 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CU254_RS03670 89c274f390d58a3f43366f883e57b509 301 Gene3D G3DSA:3.90.550.10 1 269 8.4E-34 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS08220 d567afc8902410a46733610f56215265 512 Gene3D G3DSA:1.10.10.60 434 485 4.7E-9 T 28-03-2018 CU254_RS08220 d567afc8902410a46733610f56215265 512 Gene3D G3DSA:3.30.450.40 120 260 2.4E-5 T 28-03-2018 IPR029016 GAF domain-like CU254_RS08220 d567afc8902410a46733610f56215265 512 Pfam PF13556 PucR C-terminal helix-turn-helix domain 449 503 7.3E-17 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CU254_RS08220 d567afc8902410a46733610f56215265 512 SUPERFAMILY SSF46689 408 484 8.96E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS13045 754b3d2332af14fbdd17fb473e3ad45b 341 SUPERFAMILY SSF56112 7 313 3.16E-62 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS13045 754b3d2332af14fbdd17fb473e3ad45b 341 Gene3D G3DSA:3.90.1200.10 110 297 6.4E-34 T 28-03-2018 CU254_RS13045 754b3d2332af14fbdd17fb473e3ad45b 341 Gene3D G3DSA:3.30.200.20 8 109 1.3E-28 T 28-03-2018 CU254_RS13045 754b3d2332af14fbdd17fb473e3ad45b 341 Pfam PF01636 Phosphotransferase enzyme family 33 290 1.6E-51 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CU254_RS18860 091c534d52b25f36e34693ad0d609aec 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS18860 091c534d52b25f36e34693ad0d609aec 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 4.4E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18860 091c534d52b25f36e34693ad0d609aec 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 4.4E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18860 091c534d52b25f36e34693ad0d609aec 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 4.4E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18860 091c534d52b25f36e34693ad0d609aec 258 Pfam PF00106 short chain dehydrogenase 13 198 4.4E-48 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18860 091c534d52b25f36e34693ad0d609aec 258 SUPERFAMILY SSF51735 11 243 6.0E-68 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS18860 091c534d52b25f36e34693ad0d609aec 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 9.2E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18860 091c534d52b25f36e34693ad0d609aec 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 9.2E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18860 091c534d52b25f36e34693ad0d609aec 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 9.2E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18860 091c534d52b25f36e34693ad0d609aec 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 9.2E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18860 091c534d52b25f36e34693ad0d609aec 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 9.2E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18860 091c534d52b25f36e34693ad0d609aec 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 9.2E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18860 091c534d52b25f36e34693ad0d609aec 258 Gene3D G3DSA:3.40.50.720 52 257 3.2E-52 T 28-03-2018 CU254_RS18860 091c534d52b25f36e34693ad0d609aec 258 Gene3D G3DSA:3.40.50.720 4 51 3.9E-10 T 28-03-2018 CU254_RS18860 091c534d52b25f36e34693ad0d609aec 258 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 12 187 3.5E-5 T 28-03-2018 CU254_RS05405 2a9f016c141100c0afd6b0b77adba510 254 Gene3D G3DSA:2.60.120.10 4 95 2.7E-8 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS05405 2a9f016c141100c0afd6b0b77adba510 254 Pfam PF02311 AraC-like ligand binding domain 18 109 8.9E-9 T 28-03-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 CU254_RS05405 2a9f016c141100c0afd6b0b77adba510 254 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 221 236 4.2E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CU254_RS05405 2a9f016c141100c0afd6b0b77adba510 254 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 236 252 4.2E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CU254_RS05405 2a9f016c141100c0afd6b0b77adba510 254 SUPERFAMILY SSF51182 16 167 1.11E-12 T 28-03-2018 IPR011051 RmlC-like cupin domain CU254_RS05405 2a9f016c141100c0afd6b0b77adba510 254 SUPERFAMILY SSF46689 213 254 1.08E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS05405 2a9f016c141100c0afd6b0b77adba510 254 Gene3D G3DSA:1.10.10.60 207 254 1.5E-10 T 28-03-2018 CU254_RS05405 2a9f016c141100c0afd6b0b77adba510 254 SMART SM00342 170 252 3.9E-20 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS05405 2a9f016c141100c0afd6b0b77adba510 254 Pfam PF12833 Helix-turn-helix domain 176 253 1.3E-22 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS05405 2a9f016c141100c0afd6b0b77adba510 254 Gene3D G3DSA:1.10.10.60 106 206 1.2E-8 T 28-03-2018 CU254_RS21275 008e3e7c2dead6e9ccce32342b709284 271 Gene3D G3DSA:3.30.43.10 1 54 1.7E-19 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CU254_RS21275 008e3e7c2dead6e9ccce32342b709284 271 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 6 174 3.4E-48 T 28-03-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 CU254_RS21275 008e3e7c2dead6e9ccce32342b709284 271 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 184 267 8.5E-12 T 28-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal CU254_RS21275 008e3e7c2dead6e9ccce32342b709284 271 Gene3D G3DSA:3.30.465.10 60 174 2.2E-32 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CU254_RS21275 008e3e7c2dead6e9ccce32342b709284 271 Gene3D G3DSA:3.30.390.50 177 269 2.5E-20 T 28-03-2018 CU254_RS21275 008e3e7c2dead6e9ccce32342b709284 271 SMART SM01092 180 268 5.4E-21 T 28-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal CU254_RS21275 008e3e7c2dead6e9ccce32342b709284 271 SUPERFAMILY SSF55447 178 268 8.11E-21 T 28-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal CU254_RS21275 008e3e7c2dead6e9ccce32342b709284 271 SUPERFAMILY SSF56176 3 174 4.36E-53 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CU254_RS11485 fae122adddd22ed83f2539bc3164115a 375 Gene3D G3DSA:3.40.50.880 150 375 1.8E-48 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS11485 fae122adddd22ed83f2539bc3164115a 375 SMART SM01097 7 137 1.4E-81 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CU254_RS11485 fae122adddd22ed83f2539bc3164115a 375 Gene3D G3DSA:3.50.30.20 6 149 1.3E-61 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CU254_RS11485 fae122adddd22ed83f2539bc3164115a 375 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 7 375 44.554 T 28-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CU254_RS11485 fae122adddd22ed83f2539bc3164115a 375 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 9 135 1.3E-50 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CU254_RS11485 fae122adddd22ed83f2539bc3164115a 375 SUPERFAMILY SSF52021 9 140 3.27E-53 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CU254_RS11485 fae122adddd22ed83f2539bc3164115a 375 PRINTS PR00096 Glutamine amidotransferase superfamily signature 227 236 2.3E-11 T 28-03-2018 CU254_RS11485 fae122adddd22ed83f2539bc3164115a 375 PRINTS PR00096 Glutamine amidotransferase superfamily signature 255 266 2.3E-11 T 28-03-2018 CU254_RS11485 fae122adddd22ed83f2539bc3164115a 375 PRINTS PR00096 Glutamine amidotransferase superfamily signature 346 359 2.3E-11 T 28-03-2018 CU254_RS11485 fae122adddd22ed83f2539bc3164115a 375 Pfam PF00117 Glutamine amidotransferase class-I 189 369 1.1E-36 T 28-03-2018 IPR017926 Glutamine amidotransferase CU254_RS11485 fae122adddd22ed83f2539bc3164115a 375 SUPERFAMILY SSF52317 157 372 8.1E-50 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS11485 fae122adddd22ed83f2539bc3164115a 375 PRINTS PR00097 Anthranilate synthase component II signature 227 236 5.8E-6 T 28-03-2018 CU254_RS11485 fae122adddd22ed83f2539bc3164115a 375 PRINTS PR00097 Anthranilate synthase component II signature 255 266 5.8E-6 T 28-03-2018 CU254_RS11485 fae122adddd22ed83f2539bc3164115a 375 PRINTS PR00097 Anthranilate synthase component II signature 346 359 5.8E-6 T 28-03-2018 CU254_RS11485 fae122adddd22ed83f2539bc3164115a 375 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 9 373 1.8E-136 T 28-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CU254_RS11485 fae122adddd22ed83f2539bc3164115a 375 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 255 271 1.5E-32 T 28-03-2018 CU254_RS11485 fae122adddd22ed83f2539bc3164115a 375 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 224 238 1.5E-32 T 28-03-2018 CU254_RS11485 fae122adddd22ed83f2539bc3164115a 375 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 297 308 1.5E-32 T 28-03-2018 CU254_RS11485 fae122adddd22ed83f2539bc3164115a 375 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 185 199 1.5E-32 T 28-03-2018 CU254_RS11485 fae122adddd22ed83f2539bc3164115a 375 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 272 289 1.5E-32 T 28-03-2018 CU254_RS25180 0cb47121b675c8806406f34d7523d4bf 1338 SUPERFAMILY SSF52540 1081 1251 1.31E-9 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS25180 0cb47121b675c8806406f34d7523d4bf 1338 Gene3D G3DSA:3.40.50.300 377 662 1.4E-19 T 28-03-2018 CU254_RS25180 0cb47121b675c8806406f34d7523d4bf 1338 Gene3D G3DSA:3.40.50.300 1047 1288 7.8E-5 T 28-03-2018 CU254_RS25180 0cb47121b675c8806406f34d7523d4bf 1338 Gene3D G3DSA:3.40.50.300 811 1023 1.3E-13 T 28-03-2018 CU254_RS25180 0cb47121b675c8806406f34d7523d4bf 1338 SMART SM00382 468 647 0.055 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS25180 0cb47121b675c8806406f34d7523d4bf 1338 SMART SM00382 831 1006 0.024 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS25180 0cb47121b675c8806406f34d7523d4bf 1338 SMART SM00382 1113 1276 3.3 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS25180 0cb47121b675c8806406f34d7523d4bf 1338 TIGRFAM TIGR03924 T7SS_EccC_a: type VII secretion protein EccCa 24 691 8.6E-258 T 28-03-2018 IPR023836 EccCa-like, Actinobacteria CU254_RS25180 0cb47121b675c8806406f34d7523d4bf 1338 Pfam PF01580 FtsK/SpoIIIE family 1091 1255 7.1E-7 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CU254_RS25180 0cb47121b675c8806406f34d7523d4bf 1338 Pfam PF01580 FtsK/SpoIIIE family 807 1041 1.1E-54 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CU254_RS25180 0cb47121b675c8806406f34d7523d4bf 1338 Pfam PF01580 FtsK/SpoIIIE family 434 650 2.1E-28 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CU254_RS25180 0cb47121b675c8806406f34d7523d4bf 1338 TIGRFAM TIGR03925 T7SS_EccC_b: type VII secretion protein EccCb 751 1316 8.5E-221 T 28-03-2018 IPR023837 EccCb-like, Actinobacteria CU254_RS25180 0cb47121b675c8806406f34d7523d4bf 1338 SUPERFAMILY SSF52540 438 658 4.73E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS25180 0cb47121b675c8806406f34d7523d4bf 1338 SUPERFAMILY SSF52540 784 1018 5.91E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS23025 252f4d9ea450715a7e1ff656d6f390a1 420 SUPERFAMILY SSF103473 32 417 7.19E-45 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS23025 252f4d9ea450715a7e1ff656d6f390a1 420 Pfam PF07690 Major Facilitator Superfamily 61 219 1.3E-11 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS23025 252f4d9ea450715a7e1ff656d6f390a1 420 Pfam PF07690 Major Facilitator Superfamily 251 414 8.7E-24 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS23025 252f4d9ea450715a7e1ff656d6f390a1 420 Gene3D G3DSA:1.20.1250.20 227 418 7.5E-27 T 28-03-2018 CU254_RS23025 252f4d9ea450715a7e1ff656d6f390a1 420 Gene3D G3DSA:1.20.1250.20 18 220 4.6E-20 T 28-03-2018 CU254_RS25555 221ba0e150e2e1eb0ab60f9b00e6671e 146 Pfam PF12680 SnoaL-like domain 25 120 4.3E-11 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CU254_RS25555 221ba0e150e2e1eb0ab60f9b00e6671e 146 Gene3D G3DSA:3.10.450.50 7 129 7.8E-19 T 28-03-2018 CU254_RS25555 221ba0e150e2e1eb0ab60f9b00e6671e 146 SUPERFAMILY SSF54427 9 129 7.43E-18 T 28-03-2018 IPR032710 NTF2-like domain CU254_RS27690 8628d301fba431421608edd07a4d96e6 297 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 89 5.8E-8 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CU254_RS27690 8628d301fba431421608edd07a4d96e6 297 SUPERFAMILY SSF50129 1 147 4.11E-30 T 28-03-2018 IPR011032 GroES-like CU254_RS27690 8628d301fba431421608edd07a4d96e6 297 Pfam PF13602 Zinc-binding dehydrogenase 187 295 4.4E-14 T 28-03-2018 CU254_RS27690 8628d301fba431421608edd07a4d96e6 297 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 138 159 - T 28-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 CU254_RS27690 8628d301fba431421608edd07a4d96e6 297 Gene3D G3DSA:3.90.180.10 1 145 1.6E-43 T 28-03-2018 CU254_RS27690 8628d301fba431421608edd07a4d96e6 297 Gene3D G3DSA:3.90.180.10 146 296 2.0E-15 T 28-03-2018 CU254_RS27690 8628d301fba431421608edd07a4d96e6 297 SUPERFAMILY SSF51735 111 293 1.38E-24 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS27690 8628d301fba431421608edd07a4d96e6 297 SMART SM00829 10 295 2.7E-13 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CU254_RS17270 e6085514769ed62c3ca81a4b7a2cfd77 631 Gene3D G3DSA:2.130.10.130 224 349 5.0E-4 T 28-03-2018 CU254_RS17270 e6085514769ed62c3ca81a4b7a2cfd77 631 Gene3D G3DSA:2.130.10.130 350 560 9.4E-8 T 28-03-2018 CU254_RS17270 e6085514769ed62c3ca81a4b7a2cfd77 631 Gene3D G3DSA:2.130.10.130 57 223 5.9E-15 T 28-03-2018 CU254_RS17270 e6085514769ed62c3ca81a4b7a2cfd77 631 SUPERFAMILY SSF69318 464 527 8.24E-41 T 28-03-2018 CU254_RS17270 e6085514769ed62c3ca81a4b7a2cfd77 631 SUPERFAMILY SSF69318 245 429 8.24E-41 T 28-03-2018 CU254_RS17270 e6085514769ed62c3ca81a4b7a2cfd77 631 SUPERFAMILY SSF69318 69 216 8.24E-41 T 28-03-2018 CU254_RS17270 e6085514769ed62c3ca81a4b7a2cfd77 631 Pfam PF07593 ASPIC and UnbV 553 607 5.7E-6 T 28-03-2018 IPR011519 ASPIC/UnbV CU254_RS17270 e6085514769ed62c3ca81a4b7a2cfd77 631 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 142 210 2.3E-10 T 28-03-2018 CU254_RS34565 963e606fdc80075ba6579e3e097009a8 152 Gene3D G3DSA:1.10.10.10 6 147 4.5E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS34565 963e606fdc80075ba6579e3e097009a8 152 Pfam PF12802 MarR family 42 98 8.7E-9 T 28-03-2018 CU254_RS34565 963e606fdc80075ba6579e3e097009a8 152 SMART SM00347 34 134 6.9E-4 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS34565 963e606fdc80075ba6579e3e097009a8 152 SUPERFAMILY SSF46785 33 145 1.98E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS16590 cf506d8f475783cfc90550f625c4dd56 247 SUPERFAMILY SSF46785 12 80 2.07E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS16590 cf506d8f475783cfc90550f625c4dd56 247 SUPERFAMILY SSF55781 91 242 2.09E-30 T 28-03-2018 IPR029016 GAF domain-like CU254_RS16590 cf506d8f475783cfc90550f625c4dd56 247 Pfam PF09339 IclR helix-turn-helix domain 12 58 7.7E-11 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS16590 cf506d8f475783cfc90550f625c4dd56 247 SMART SM00346 8 97 9.6E-5 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS16590 cf506d8f475783cfc90550f625c4dd56 247 Gene3D G3DSA:1.10.10.10 1 78 8.4E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS16590 cf506d8f475783cfc90550f625c4dd56 247 Pfam PF01614 Bacterial transcriptional regulator 126 242 2.0E-11 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal CU254_RS16590 cf506d8f475783cfc90550f625c4dd56 247 Gene3D G3DSA:3.30.450.40 87 246 2.1E-31 T 28-03-2018 IPR029016 GAF domain-like CU254_RS12175 7c49774fedd5a1f1b6ef8394463f714d 172 Pfam PF12802 MarR family 53 114 5.8E-15 T 28-03-2018 CU254_RS12175 7c49774fedd5a1f1b6ef8394463f714d 172 PRINTS PR00598 Bacterial regulatory protein MarR family signature 141 161 1.2E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS12175 7c49774fedd5a1f1b6ef8394463f714d 172 PRINTS PR00598 Bacterial regulatory protein MarR family signature 111 127 1.2E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS12175 7c49774fedd5a1f1b6ef8394463f714d 172 PRINTS PR00598 Bacterial regulatory protein MarR family signature 92 107 1.2E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS12175 7c49774fedd5a1f1b6ef8394463f714d 172 Gene3D G3DSA:1.10.10.10 3 170 8.4E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS12175 7c49774fedd5a1f1b6ef8394463f714d 172 SUPERFAMILY SSF46785 18 167 9.02E-35 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS12175 7c49774fedd5a1f1b6ef8394463f714d 172 SMART SM00347 48 151 7.3E-18 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS20110 d9978ebce9d2f13eb808275df2d3acd8 144 SUPERFAMILY SSF55874 40 139 5.69E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS20110 d9978ebce9d2f13eb808275df2d3acd8 144 Pfam PF13581 Histidine kinase-like ATPase domain 32 138 2.4E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS20110 d9978ebce9d2f13eb808275df2d3acd8 144 Gene3D G3DSA:3.30.565.10 20 144 2.1E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS37020 2b415e116333f8d10439d45614b1af25 331 SMART SM00382 33 231 1.1E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS37020 2b415e116333f8d10439d45614b1af25 331 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 299 1.2E-17 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CU254_RS37020 2b415e116333f8d10439d45614b1af25 331 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS37020 2b415e116333f8d10439d45614b1af25 331 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 317 4.4E-19 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CU254_RS37020 2b415e116333f8d10439d45614b1af25 331 Pfam PF00005 ABC transporter 25 182 8.0E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS37020 2b415e116333f8d10439d45614b1af25 331 Gene3D G3DSA:3.40.50.300 1 319 5.2E-74 T 28-03-2018 CU254_RS37020 2b415e116333f8d10439d45614b1af25 331 SUPERFAMILY SSF52540 3 253 6.02E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS06690 bf18f7521a5bbb280d1c069cd5249346 163 ProSitePatterns PS00763 Glutathione peroxidases signature 2. 60 67 - T 28-03-2018 IPR029760 Glutathione peroxidase conserved site Reactome: R-HSA-3299685 CU254_RS06690 bf18f7521a5bbb280d1c069cd5249346 163 SUPERFAMILY SSF52833 3 161 1.1E-52 T 28-03-2018 IPR012336 Thioredoxin-like fold CU254_RS06690 bf18f7521a5bbb280d1c069cd5249346 163 PRINTS PR01011 Glutathione peroxidase family signature 57 73 7.7E-19 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CU254_RS06690 bf18f7521a5bbb280d1c069cd5249346 163 PRINTS PR01011 Glutathione peroxidase family signature 123 132 7.7E-19 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CU254_RS06690 bf18f7521a5bbb280d1c069cd5249346 163 PRINTS PR01011 Glutathione peroxidase family signature 22 39 7.7E-19 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CU254_RS06690 bf18f7521a5bbb280d1c069cd5249346 163 PIRSF PIRSF000303 1 163 1.8E-58 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CU254_RS06690 bf18f7521a5bbb280d1c069cd5249346 163 Pfam PF00255 Glutathione peroxidase 7 109 1.5E-38 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CU254_RS06690 bf18f7521a5bbb280d1c069cd5249346 163 ProSitePatterns PS00460 Glutathione peroxidases active site. 24 39 - T 28-03-2018 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 CU254_RS06690 bf18f7521a5bbb280d1c069cd5249346 163 Gene3D G3DSA:3.40.30.10 2 163 5.7E-43 T 28-03-2018 CU254_RS25375 9647087cf3a432036b107598031e0119 316 Pfam PF06675 Protein of unknown function (DUF1177) 42 311 2.2E-129 T 28-03-2018 IPR009561 Protein of unknown function DUF1177 CU254_RS19320 c908375ab45bf70e8f529ce33b90359e 372 Gene3D G3DSA:1.20.1250.20 179 371 7.2E-16 T 28-03-2018 CU254_RS19320 c908375ab45bf70e8f529ce33b90359e 372 Pfam PF07690 Major Facilitator Superfamily 9 283 4.7E-18 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS19320 c908375ab45bf70e8f529ce33b90359e 372 Gene3D G3DSA:1.20.1250.20 1 178 1.1E-17 T 28-03-2018 CU254_RS19320 c908375ab45bf70e8f529ce33b90359e 372 SUPERFAMILY SSF103473 2 369 9.42E-44 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS38125 1e6078b5c3b20776e357c0ce55689a24 274 Gene3D G3DSA:2.60.40.10 1 76 1.0E-12 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS38125 1e6078b5c3b20776e357c0ce55689a24 274 Pfam PF04264 YceI-like domain 99 265 7.7E-34 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CU254_RS38125 1e6078b5c3b20776e357c0ce55689a24 274 Pfam PF13620 Carboxypeptidase regulatory-like domain 8 76 2.9E-9 T 28-03-2018 CU254_RS38125 1e6078b5c3b20776e357c0ce55689a24 274 Gene3D G3DSA:2.40.128.110 95 273 5.3E-47 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CU254_RS38125 1e6078b5c3b20776e357c0ce55689a24 274 SUPERFAMILY SSF101874 97 268 2.75E-46 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CU254_RS38125 1e6078b5c3b20776e357c0ce55689a24 274 SUPERFAMILY SSF49478 11 74 3.06E-11 T 28-03-2018 CU254_RS38125 1e6078b5c3b20776e357c0ce55689a24 274 SMART SM00867 98 266 5.3E-53 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CU254_RS06805 d33bae20d28ca23dbc505d6e8787d1ae 99 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 20 91 1.6E-18 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CU254_RS06805 d33bae20d28ca23dbc505d6e8787d1ae 99 SUPERFAMILY SSF141000 4 94 8.76E-29 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CU254_RS06805 d33bae20d28ca23dbc505d6e8787d1ae 99 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 3 96 24.16 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CU254_RS06805 d33bae20d28ca23dbc505d6e8787d1ae 99 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 4 95 3.2E-26 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CU254_RS31535 6a354a3917e27cb21edc8fc890c0700f 402 SUPERFAMILY SSF48264 4 402 9.95E-96 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS31535 6a354a3917e27cb21edc8fc890c0700f 402 PRINTS PR00385 P450 superfamily signature 351 362 7.9E-8 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS31535 6a354a3917e27cb21edc8fc890c0700f 402 PRINTS PR00385 P450 superfamily signature 342 351 7.9E-8 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS31535 6a354a3917e27cb21edc8fc890c0700f 402 PRINTS PR00385 P450 superfamily signature 276 287 7.9E-8 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS31535 6a354a3917e27cb21edc8fc890c0700f 402 PRINTS PR00385 P450 superfamily signature 241 258 7.9E-8 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS31535 6a354a3917e27cb21edc8fc890c0700f 402 Gene3D G3DSA:1.10.630.10 10 402 6.1E-76 T 28-03-2018 CU254_RS31535 6a354a3917e27cb21edc8fc890c0700f 402 PRINTS PR00359 B-class P450 signature 351 362 3.4E-57 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS31535 6a354a3917e27cb21edc8fc890c0700f 402 PRINTS PR00359 B-class P450 signature 321 336 3.4E-57 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS31535 6a354a3917e27cb21edc8fc890c0700f 402 PRINTS PR00359 B-class P450 signature 342 351 3.4E-57 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS31535 6a354a3917e27cb21edc8fc890c0700f 402 PRINTS PR00359 B-class P450 signature 199 221 3.4E-57 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS31535 6a354a3917e27cb21edc8fc890c0700f 402 PRINTS PR00359 B-class P450 signature 293 320 3.4E-57 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS31535 6a354a3917e27cb21edc8fc890c0700f 402 PRINTS PR00359 B-class P450 signature 162 177 3.4E-57 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS31535 6a354a3917e27cb21edc8fc890c0700f 402 PRINTS PR00359 B-class P450 signature 276 287 3.4E-57 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS31535 6a354a3917e27cb21edc8fc890c0700f 402 PRINTS PR00359 B-class P450 signature 98 109 3.4E-57 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS31535 6a354a3917e27cb21edc8fc890c0700f 402 PRINTS PR00359 B-class P450 signature 145 161 3.4E-57 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS31535 6a354a3917e27cb21edc8fc890c0700f 402 Pfam PF00067 Cytochrome P450 222 373 2.0E-22 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS31535 6a354a3917e27cb21edc8fc890c0700f 402 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 344 353 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CU254_RS38545 29a1cd89608dfadd7ca6110445bdeed8 280 Gene3D G3DSA:3.90.260.10 153 272 3.9E-10 T 28-03-2018 IPR002931 Transglutaminase-like CU254_RS38545 29a1cd89608dfadd7ca6110445bdeed8 280 Pfam PF01841 Transglutaminase-like superfamily 128 233 1.1E-24 T 28-03-2018 IPR002931 Transglutaminase-like CU254_RS38545 29a1cd89608dfadd7ca6110445bdeed8 280 SMART SM00460 168 235 6.2E-19 T 28-03-2018 IPR002931 Transglutaminase-like CU254_RS38545 29a1cd89608dfadd7ca6110445bdeed8 280 SUPERFAMILY SSF54001 9 262 1.07E-39 T 28-03-2018 CU254_RS38545 29a1cd89608dfadd7ca6110445bdeed8 280 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 5 83 5.1E-21 T 28-03-2018 IPR013589 Bacterial transglutaminase-like, N-terminal CU254_RS34915 224bb8106332600a9f0973ab3c2f419c 457 Pfam PF13520 Amino acid permease 25 410 6.3E-45 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CU254_RS34915 224bb8106332600a9f0973ab3c2f419c 457 PIRSF PIRSF006060 2 456 9.5E-77 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CU254_RS08800 2843e4149c497d126131912ca54abae0 208 Pfam PF04167 Protein of unknown function (DUF402) 85 149 3.8E-14 T 28-03-2018 IPR007295 Domain of unknown function DUF402 CU254_RS08800 2843e4149c497d126131912ca54abae0 208 SUPERFAMILY SSF159234 11 199 4.32E-28 T 28-03-2018 IPR007295 Domain of unknown function DUF402 CU254_RS08800 2843e4149c497d126131912ca54abae0 208 Gene3D G3DSA:2.40.380.10 4 197 3.3E-55 T 28-03-2018 IPR007295 Domain of unknown function DUF402 CU254_RS00975 a4a5cf1f57255369249853618cbcff2c 183 SUPERFAMILY SSF109854 7 75 5.49E-5 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CU254_RS00975 a4a5cf1f57255369249853618cbcff2c 183 Pfam PF07398 MDMPI C-terminal domain 93 169 1.3E-11 T 28-03-2018 IPR010872 MDMPI C-terminal CU254_RS00975 a4a5cf1f57255369249853618cbcff2c 183 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 11 78 3.5E-5 T 28-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CU254_RS00975 a4a5cf1f57255369249853618cbcff2c 183 Gene3D G3DSA:1.20.120.450 3 83 4.3E-9 T 28-03-2018 CU254_RS03680 4f6fd9ad9bae8c0b2d581034caa78fb5 507 SUPERFAMILY SSF90123 3 289 1.96E-26 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CU254_RS03680 4f6fd9ad9bae8c0b2d581034caa78fb5 507 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 3 479 2.1E-110 T 28-03-2018 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0006810|GO:0016021|GO:0042626 CU254_RS03680 4f6fd9ad9bae8c0b2d581034caa78fb5 507 Gene3D G3DSA:3.40.50.300 277 502 1.5E-50 T 28-03-2018 CU254_RS03680 4f6fd9ad9bae8c0b2d581034caa78fb5 507 SUPERFAMILY SSF52540 284 498 2.17E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS03680 4f6fd9ad9bae8c0b2d581034caa78fb5 507 Gene3D G3DSA:1.20.1560.10 1 276 1.9E-16 T 28-03-2018 CU254_RS03680 4f6fd9ad9bae8c0b2d581034caa78fb5 507 SMART SM00382 321 495 1.8E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS03680 4f6fd9ad9bae8c0b2d581034caa78fb5 507 Pfam PF00005 ABC transporter 312 449 5.6E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS03680 4f6fd9ad9bae8c0b2d581034caa78fb5 507 ProSitePatterns PS00211 ABC transporters family signature. 422 436 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS05320 46358a3ef84dc417edf031637338f6e1 373 PRINTS PR00412 Epoxide hydrolase signature 346 368 1.8E-16 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS05320 46358a3ef84dc417edf031637338f6e1 373 PRINTS PR00412 Epoxide hydrolase signature 127 142 1.8E-16 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS05320 46358a3ef84dc417edf031637338f6e1 373 PRINTS PR00412 Epoxide hydrolase signature 172 185 1.8E-16 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS05320 46358a3ef84dc417edf031637338f6e1 373 PRINTS PR00412 Epoxide hydrolase signature 98 116 1.8E-16 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS05320 46358a3ef84dc417edf031637338f6e1 373 PRINTS PR00412 Epoxide hydrolase signature 186 199 1.8E-16 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS05320 46358a3ef84dc417edf031637338f6e1 373 Pfam PF06441 Epoxide hydrolase N terminus 4 107 5.3E-29 T 28-03-2018 IPR010497 Epoxide hydrolase, N-terminal KEGG: 00980+3.3.2.9|Reactome: R-HSA-211945 CU254_RS05320 46358a3ef84dc417edf031637338f6e1 373 PIRSF PIRSF001112 1 373 1.9E-117 T 28-03-2018 IPR016292 Epoxide hydrolase GO:0033961 KEGG: 00980+3.3.2.9|Reactome: R-HSA-211945 CU254_RS05320 46358a3ef84dc417edf031637338f6e1 373 SUPERFAMILY SSF53474 2 370 1.42E-92 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS05320 46358a3ef84dc417edf031637338f6e1 373 Gene3D G3DSA:3.40.50.1820 1 373 3.7E-69 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS24015 a74f160bc347eab917f262f238e0d5d6 499 Pfam PF00890 FAD binding domain 8 479 1.1E-68 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CU254_RS24015 a74f160bc347eab917f262f238e0d5d6 499 SUPERFAMILY SSF56425 287 438 8.79E-27 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CU254_RS24015 a74f160bc347eab917f262f238e0d5d6 499 SUPERFAMILY SSF51905 432 497 3.85E-29 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS24015 a74f160bc347eab917f262f238e0d5d6 499 SUPERFAMILY SSF51905 161 268 3.85E-29 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS24015 a74f160bc347eab917f262f238e0d5d6 499 SUPERFAMILY SSF51905 1 123 3.85E-29 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS24015 a74f160bc347eab917f262f238e0d5d6 499 Gene3D G3DSA:3.50.50.60 2 494 1.5E-57 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS24015 a74f160bc347eab917f262f238e0d5d6 499 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 8 30 1.0E-5 T 28-03-2018 CU254_RS24015 a74f160bc347eab917f262f238e0d5d6 499 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 454 469 1.0E-5 T 28-03-2018 CU254_RS16260 ded1904bf3d523bb24708808ccacdd39 178 SUPERFAMILY SSF46689 11 94 1.89E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS16260 ded1904bf3d523bb24708808ccacdd39 178 Gene3D G3DSA:1.10.10.60 10 70 1.3E-15 T 28-03-2018 CU254_RS16260 ded1904bf3d523bb24708808ccacdd39 178 Gene3D G3DSA:1.10.357.10 71 177 4.4E-4 T 28-03-2018 CU254_RS16260 ded1904bf3d523bb24708808ccacdd39 178 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 70 1.4E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS23505 d3c641ba41850ab82b63b2ac432b949c 172 Pfam PF01047 MarR family 41 95 4.5E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS23505 d3c641ba41850ab82b63b2ac432b949c 172 PRINTS PR00598 Bacterial regulatory protein MarR family signature 72 87 5.3E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS23505 d3c641ba41850ab82b63b2ac432b949c 172 PRINTS PR00598 Bacterial regulatory protein MarR family signature 121 141 5.3E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS23505 d3c641ba41850ab82b63b2ac432b949c 172 PRINTS PR00598 Bacterial regulatory protein MarR family signature 91 107 5.3E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS23505 d3c641ba41850ab82b63b2ac432b949c 172 PRINTS PR00598 Bacterial regulatory protein MarR family signature 55 71 5.3E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS23505 d3c641ba41850ab82b63b2ac432b949c 172 SMART SM00347 31 131 3.6E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS23505 d3c641ba41850ab82b63b2ac432b949c 172 SUPERFAMILY SSF46785 16 143 1.37E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS23505 d3c641ba41850ab82b63b2ac432b949c 172 Gene3D G3DSA:1.10.10.10 11 145 2.8E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS34435 96f8714baba6d5480cfddd8716256def 493 SUPERFAMILY SSF89796 232 429 1.96E-46 T 28-03-2018 IPR023606 CoA-transferase family III domain CU254_RS34435 96f8714baba6d5480cfddd8716256def 493 SUPERFAMILY SSF89796 48 227 7.19E-18 T 28-03-2018 IPR023606 CoA-transferase family III domain CU254_RS34435 96f8714baba6d5480cfddd8716256def 493 Pfam PF02515 CoA-transferase family III 234 432 3.6E-37 T 28-03-2018 IPR003673 CoA-transferase family III GO:0003824 CU254_RS34435 96f8714baba6d5480cfddd8716256def 493 Gene3D G3DSA:3.40.50.10540 221 491 7.9E-52 T 28-03-2018 IPR023606 CoA-transferase family III domain CU254_RS34435 96f8714baba6d5480cfddd8716256def 493 Gene3D G3DSA:3.40.50.10540 25 213 5.1E-7 T 28-03-2018 IPR023606 CoA-transferase family III domain CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 Gene3D G3DSA:3.40.50.720 3163 3405 4.9E-47 T 28-03-2018 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 Gene3D G3DSA:3.40.50.720 4862 5100 6.6E-49 T 28-03-2018 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 Gene3D G3DSA:3.40.50.720 1438 1687 9.7E-45 T 28-03-2018 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 SUPERFAMILY SSF52151 832 926 2.22E-72 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 SUPERFAMILY SSF52151 643 771 2.22E-72 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 SUPERFAMILY SSF51735 4865 5089 3.24E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 SMART SM00825 Beta-ketoacyl synthase 1825 2250 1.6E-222 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 SMART SM00825 Beta-ketoacyl synthase 3540 3964 4.5E-205 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 SMART SM00825 Beta-ketoacyl synthase 124 548 8.3E-216 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 4069 4365 8.0E-120 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 647 937 6.8E-114 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2345 2640 1.1E-119 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3473 3488 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 SUPERFAMILY SSF47336 1729 1838 5.23E-25 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 Gene3D G3DSA:3.30.70.250 779 822 2.7E-18 T 28-03-2018 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 Gene3D G3DSA:3.30.70.250 4202 4242 1.6E-18 T 28-03-2018 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 Gene3D G3DSA:3.30.70.250 2486 2529 4.9E-14 T 28-03-2018 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 SUPERFAMILY SSF53901 3533 3908 3.85E-100 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 ProSitePatterns PS00012 Phosphopantetheine attachment site. 5166 5181 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 SUPERFAMILY SSF51735 2979 3156 6.3E-27 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 Gene3D G3DSA:3.10.129.10 1005 1125 2.9E-9 T 28-03-2018 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 Gene3D G3DSA:3.10.129.10 2704 2829 4.0E-7 T 28-03-2018 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 Gene3D G3DSA:3.10.129.10 4434 4551 9.7E-10 T 28-03-2018 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 SMART SM01294 5140 5207 6.4E-4 T 28-03-2018 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 SMART SM01294 1733 1800 1.9E-4 T 28-03-2018 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 SMART SM01294 38 100 1.4E-4 T 28-03-2018 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 SMART SM01294 3447 3514 2.5E-6 T 28-03-2018 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 Pfam PF00698 Acyl transferase domain 4068 4371 7.1E-55 T 28-03-2018 IPR014043 Acyl transferase CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 Pfam PF00698 Acyl transferase domain 647 954 1.6E-55 T 28-03-2018 IPR014043 Acyl transferase CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 Pfam PF00698 Acyl transferase domain 2344 2657 7.0E-59 T 28-03-2018 IPR014043 Acyl transferase CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 SMART SM00823 Phosphopantetheine attachment site 3446 3518 2.4E-31 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 SMART SM00823 Phosphopantetheine attachment site 34 104 1.6E-21 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 SMART SM00823 Phosphopantetheine attachment site 5139 5211 1.7E-29 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 SMART SM00823 Phosphopantetheine attachment site 1732 1804 1.7E-32 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 SUPERFAMILY SSF51735 1440 1700 1.69E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 SUPERFAMILY SSF51735 4702 4857 1.18E-26 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 Pfam PF08659 KR domain 3166 3342 1.2E-55 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 Pfam PF08659 KR domain 1445 1621 1.3E-55 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 Pfam PF08659 KR domain 4869 5043 4.5E-58 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 Gene3D G3DSA:3.40.366.10 2530 2647 1.4E-26 T 28-03-2018 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 SUPERFAMILY SSF55048 2473 2534 6.02E-9 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 Gene3D G3DSA:3.40.366.10 4065 4201 8.4E-44 T 28-03-2018 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 Gene3D G3DSA:3.40.366.10 643 778 7.5E-45 T 28-03-2018 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 SUPERFAMILY SSF51735 3165 3415 1.27E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 Pfam PF14765 Polyketide synthase dehydratase 2704 2971 4.9E-57 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 Pfam PF14765 Polyketide synthase dehydratase 4432 4698 9.3E-51 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 Pfam PF14765 Polyketide synthase dehydratase 1002 1272 7.8E-53 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 SUPERFAMILY SSF52151 4245 4348 3.14E-72 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 SUPERFAMILY SSF52151 4066 4186 3.14E-72 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 SUPERFAMILY SSF55048 4191 4252 1.1E-11 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 SUPERFAMILY SSF53901 119 492 2.82E-101 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 SUPERFAMILY SSF51735 1279 1432 1.14E-16 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 SUPERFAMILY SSF47336 5133 5216 1.24E-20 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1986 2002 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 Gene3D G3DSA:3.40.366.10 2338 2485 2.9E-46 T 28-03-2018 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 Gene3D G3DSA:1.10.1200.10 3437 3536 7.3E-20 T 28-03-2018 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 Gene3D G3DSA:1.10.1200.10 5132 5244 1.1E-19 T 28-03-2018 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 Gene3D G3DSA:3.40.366.10 823 945 5.8E-26 T 28-03-2018 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 Gene3D G3DSA:3.40.366.10 4243 4360 2.5E-31 T 28-03-2018 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1759 1774 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 Gene3D G3DSA:1.10.1200.10 1705 1807 8.4E-21 T 28-03-2018 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 Gene3D G3DSA:1.10.1200.10 2 104 9.1E-15 T 28-03-2018 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 380 495 9.0E-45 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3796 3911 1.6E-39 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2081 2198 4.7E-45 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 SUPERFAMILY SSF53901 1819 2195 3.09E-102 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 SUPERFAMILY SSF47336 37 136 4.84E-20 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3701 3717 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 Gene3D G3DSA:3.40.47.10 3803 3962 3.3E-58 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 Gene3D G3DSA:3.40.47.10 2088 2248 1.2E-63 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 Gene3D G3DSA:3.40.47.10 387 546 2.3E-63 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 SUPERFAMILY SSF47336 3442 3553 6.02E-24 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1445 1623 7.0E-51 T 28-03-2018 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4869 5045 7.2E-50 T 28-03-2018 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3166 3343 1.5E-53 T 28-03-2018 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 SUPERFAMILY SSF55048 770 831 3.27E-11 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 SUPERFAMILY SSF52151 2341 2473 2.88E-71 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 SUPERFAMILY SSF52151 2536 2628 2.88E-71 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3538 3788 3.9E-86 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 122 372 1.3E-85 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1823 2073 2.9E-88 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 Gene3D G3DSA:3.40.47.10 3537 3800 6.4E-82 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 Gene3D G3DSA:3.40.47.10 1816 2085 1.2E-85 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 Gene3D G3DSA:3.40.47.10 114 384 2.8E-82 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 SMART SM00826 4432 4587 2.2E-75 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 SMART SM00826 2704 2864 9.4E-79 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 SMART SM00826 1002 1163 3.5E-75 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 Pfam PF00550 Phosphopantetheine attachment site 39 100 6.1E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 Pfam PF00550 Phosphopantetheine attachment site 5142 5207 4.3E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 Pfam PF00550 Phosphopantetheine attachment site 3448 3514 8.0E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 Pfam PF00550 Phosphopantetheine attachment site 1734 1800 3.0E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3914 4031 6.3E-14 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2201 2313 5.2E-15 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS30145 b2a961bbcf003bfe9aa041af5dd31f66 5256 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 498 611 3.1E-16 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS11890 754e5be47794d416bea6c8ad51886951 934 SUPERFAMILY SSF49785 805 911 1.98E-11 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS11890 754e5be47794d416bea6c8ad51886951 934 Gene3D G3DSA:2.60.40.10 644 748 2.3E-9 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS11890 754e5be47794d416bea6c8ad51886951 934 SUPERFAMILY SSF52743 178 321 3.01E-28 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS11890 754e5be47794d416bea6c8ad51886951 934 SUPERFAMILY SSF52743 514 629 3.01E-28 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS11890 754e5be47794d416bea6c8ad51886951 934 SUPERFAMILY SSF52743 464 487 3.01E-28 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS11890 754e5be47794d416bea6c8ad51886951 934 Gene3D G3DSA:2.60.120.260 751 932 2.3E-20 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS11890 754e5be47794d416bea6c8ad51886951 934 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 569 579 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CU254_RS11890 754e5be47794d416bea6c8ad51886951 934 Pfam PF00082 Subtilase family 247 619 2.1E-14 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS11890 754e5be47794d416bea6c8ad51886951 934 Gene3D G3DSA:3.40.50.200 177 640 9.5E-34 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS11890 754e5be47794d416bea6c8ad51886951 934 Pfam PF01483 Proprotein convertase P-domain 806 907 5.7E-8 T 28-03-2018 IPR002884 Proprotein convertase, P GO:0004252|GO:0006508 CU254_RS28150 e59cd9e8b7455763948d2813a4d2062b 251 Pfam PF00106 short chain dehydrogenase 6 199 4.1E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS28150 e59cd9e8b7455763948d2813a4d2062b 251 Gene3D G3DSA:3.40.50.720 4 250 2.1E-48 T 28-03-2018 CU254_RS28150 e59cd9e8b7455763948d2813a4d2062b 251 SUPERFAMILY SSF51735 6 248 1.5E-56 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS28150 e59cd9e8b7455763948d2813a4d2062b 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 2.3E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS28150 e59cd9e8b7455763948d2813a4d2062b 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 2.3E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS28150 e59cd9e8b7455763948d2813a4d2062b 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 2.3E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS28150 e59cd9e8b7455763948d2813a4d2062b 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 4.4E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS28150 e59cd9e8b7455763948d2813a4d2062b 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 4.4E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS28150 e59cd9e8b7455763948d2813a4d2062b 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 4.4E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS28150 e59cd9e8b7455763948d2813a4d2062b 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 4.4E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS28150 e59cd9e8b7455763948d2813a4d2062b 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 4.4E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS30625 82293b20ed0fd8ad2f6023cd3a2cc853 352 Gene3D G3DSA:2.30.40.10 293 352 4.3E-9 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS30625 82293b20ed0fd8ad2f6023cd3a2cc853 352 SUPERFAMILY SSF51338 4 51 8.87E-12 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS30625 82293b20ed0fd8ad2f6023cd3a2cc853 352 SUPERFAMILY SSF51338 313 343 8.87E-12 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS30625 82293b20ed0fd8ad2f6023cd3a2cc853 352 Gene3D G3DSA:2.30.40.10 2 68 6.3E-14 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS30625 82293b20ed0fd8ad2f6023cd3a2cc853 352 SUPERFAMILY SSF51556 50 312 1.32E-40 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS30625 82293b20ed0fd8ad2f6023cd3a2cc853 352 Pfam PF01979 Amidohydrolase family 47 348 6.4E-19 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CU254_RS30625 82293b20ed0fd8ad2f6023cd3a2cc853 352 Gene3D G3DSA:3.20.20.140 69 292 4.8E-22 T 28-03-2018 CU254_RS04695 d2174115ddb4eea6800ea565ec074eae 223 Pfam PF13419 Haloacid dehalogenase-like hydrolase 10 186 6.6E-20 T 28-03-2018 IPR023214 HAD-like domain CU254_RS04695 d2174115ddb4eea6800ea565ec074eae 223 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 79 186 1.3E-14 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CU254_RS04695 d2174115ddb4eea6800ea565ec074eae 223 Gene3D G3DSA:1.10.150.240 20 79 7.3E-12 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CU254_RS04695 d2174115ddb4eea6800ea565ec074eae 223 Gene3D G3DSA:3.40.50.1000 80 220 2.9E-25 T 28-03-2018 IPR023214 HAD-like domain CU254_RS04695 d2174115ddb4eea6800ea565ec074eae 223 SUPERFAMILY SSF56784 7 214 3.4E-44 T 28-03-2018 IPR023214 HAD-like domain CU254_RS18815 30af62e7efd2540a9c13c73be3f565aa 484 PIRSF PIRSF006060 5 482 1.7E-51 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CU254_RS18815 30af62e7efd2540a9c13c73be3f565aa 484 Pfam PF13520 Amino acid permease 24 438 1.7E-25 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CU254_RS30305 3819c2a967c6aaa1575da63451df28e9 273 Pfam PF08241 Methyltransferase domain 51 144 6.3E-23 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CU254_RS30305 3819c2a967c6aaa1575da63451df28e9 273 Gene3D G3DSA:3.40.50.150 3 255 3.9E-33 T 28-03-2018 CU254_RS30305 3819c2a967c6aaa1575da63451df28e9 273 SUPERFAMILY SSF53335 29 219 6.48E-36 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS07440 f6e48a03681c2aac888f2a806186ccac 653 SUPERFAMILY SSF51735 367 588 2.03E-58 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS07440 f6e48a03681c2aac888f2a806186ccac 653 SUPERFAMILY SSF51735 1 286 5.0E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS07440 f6e48a03681c2aac888f2a806186ccac 653 Gene3D G3DSA:3.40.50.720 340 601 3.8E-53 T 28-03-2018 CU254_RS07440 f6e48a03681c2aac888f2a806186ccac 653 Gene3D G3DSA:3.40.50.720 2 330 4.3E-44 T 28-03-2018 CU254_RS07440 f6e48a03681c2aac888f2a806186ccac 653 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 371 562 8.1E-4 T 28-03-2018 CU254_RS07440 f6e48a03681c2aac888f2a806186ccac 653 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 542 559 1.4E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS07440 f6e48a03681c2aac888f2a806186ccac 653 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 372 389 1.4E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS07440 f6e48a03681c2aac888f2a806186ccac 653 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 495 511 1.4E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS07440 f6e48a03681c2aac888f2a806186ccac 653 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 521 540 1.4E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS07440 f6e48a03681c2aac888f2a806186ccac 653 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 446 457 1.4E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS07440 f6e48a03681c2aac888f2a806186ccac 653 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 501 509 1.0E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS07440 f6e48a03681c2aac888f2a806186ccac 653 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 446 457 1.0E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS07440 f6e48a03681c2aac888f2a806186ccac 653 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 521 540 1.0E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS07440 f6e48a03681c2aac888f2a806186ccac 653 Pfam PF00106 short chain dehydrogenase 372 561 4.0E-47 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS07440 f6e48a03681c2aac888f2a806186ccac 653 Pfam PF07993 Male sterility protein 6 231 2.6E-45 T 28-03-2018 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 CU254_RS40100 51acd35187e57b1826b2a26a49d37004 315 Gene3D G3DSA:1.25.40.240 209 306 0.0018 T 28-03-2018 CU254_RS40100 51acd35187e57b1826b2a26a49d37004 315 Gene3D G3DSA:1.25.40.10 17 198 1.7E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS10715 87fe300266cf9e093d8e7a41589fa729 189 Gene3D G3DSA:1.10.472.50 1 89 1.4E-12 T 28-03-2018 CU254_RS10715 87fe300266cf9e093d8e7a41589fa729 189 SUPERFAMILY SSF109604 4 171 1.39E-28 T 28-03-2018 CU254_RS10715 87fe300266cf9e093d8e7a41589fa729 189 PIRSF PIRSF035170 1 184 1.1E-48 T 28-03-2018 IPR009218 Predicted HD phosphohydrolase CU254_RS05840 fed21c976560208abcf09570f8c1af8f 486 Pfam PF00743 Flavin-binding monooxygenase-like 87 452 1.2E-22 T 28-03-2018 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 CU254_RS05840 fed21c976560208abcf09570f8c1af8f 486 SUPERFAMILY SSF51905 236 401 2.2E-6 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS05840 fed21c976560208abcf09570f8c1af8f 486 Gene3D G3DSA:3.50.50.60 85 236 1.1E-19 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS05840 fed21c976560208abcf09570f8c1af8f 486 Gene3D G3DSA:3.50.50.60 376 423 0.34 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS05840 fed21c976560208abcf09570f8c1af8f 486 Gene3D G3DSA:3.50.50.60 237 375 1.6E-14 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS05840 fed21c976560208abcf09570f8c1af8f 486 PIRSF PIRSF000332 85 461 2.8E-23 T 28-03-2018 CU254_RS05840 fed21c976560208abcf09570f8c1af8f 486 SUPERFAMILY SSF51905 86 293 9.55E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS05840 fed21c976560208abcf09570f8c1af8f 486 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 375 402 3.4E-12 T 28-03-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 CU254_RS05840 fed21c976560208abcf09570f8c1af8f 486 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 86 102 3.4E-12 T 28-03-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 CU254_RS05840 fed21c976560208abcf09570f8c1af8f 486 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 110 134 3.4E-12 T 28-03-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 CU254_RS05840 fed21c976560208abcf09570f8c1af8f 486 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 210 226 3.4E-12 T 28-03-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 CU254_RS05840 fed21c976560208abcf09570f8c1af8f 486 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 265 280 3.4E-12 T 28-03-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 CU254_RS11900 7beee480e66201a9f48fd57f267a8a54 542 Pfam PF00005 ABC transporter 353 481 3.9E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS11900 7beee480e66201a9f48fd57f267a8a54 542 Pfam PF00005 ABC transporter 17 197 1.3E-20 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS11900 7beee480e66201a9f48fd57f267a8a54 542 ProSitePatterns PS00211 ABC transporters family signature. 453 467 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS11900 7beee480e66201a9f48fd57f267a8a54 542 SUPERFAMILY SSF52540 3 241 9.03E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS11900 7beee480e66201a9f48fd57f267a8a54 542 Gene3D G3DSA:3.40.50.300 1 301 1.4E-44 T 28-03-2018 CU254_RS11900 7beee480e66201a9f48fd57f267a8a54 542 Pfam PF12848 ABC transporter 239 314 1.3E-7 T 28-03-2018 IPR032781 ABC-transporter extension domain CU254_RS11900 7beee480e66201a9f48fd57f267a8a54 542 SMART SM00382 360 527 2.6E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS11900 7beee480e66201a9f48fd57f267a8a54 542 SMART SM00382 26 242 1.9E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS11900 7beee480e66201a9f48fd57f267a8a54 542 SUPERFAMILY SSF52540 341 526 4.39E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS11900 7beee480e66201a9f48fd57f267a8a54 542 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS11900 7beee480e66201a9f48fd57f267a8a54 542 Gene3D G3DSA:3.40.50.300 302 540 3.4E-50 T 28-03-2018 CU254_RS42340 16de884a5ea7977b738a4df74e5cf379 267 SUPERFAMILY SSF53474 4 255 1.08E-54 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS42340 16de884a5ea7977b738a4df74e5cf379 267 Gene3D G3DSA:3.40.50.1820 3 256 1.6E-43 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS42340 16de884a5ea7977b738a4df74e5cf379 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 201 215 6.7E-10 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS42340 16de884a5ea7977b738a4df74e5cf379 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 90 103 6.7E-10 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS42340 16de884a5ea7977b738a4df74e5cf379 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 6.7E-10 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS42340 16de884a5ea7977b738a4df74e5cf379 267 PRINTS PR00111 Alpha/beta hydrolase fold signature 46 61 6.7E-10 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS42340 16de884a5ea7977b738a4df74e5cf379 267 Pfam PF12697 Alpha/beta hydrolase family 23 251 8.4E-20 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS12020 529ef16d621bdc50addc0d10cd18cdbd 397 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 352 371 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CU254_RS12020 529ef16d621bdc50addc0d10cd18cdbd 397 SUPERFAMILY SSF47203 244 393 1.14E-41 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS12020 529ef16d621bdc50addc0d10cd18cdbd 397 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 22 135 6.5E-27 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS12020 529ef16d621bdc50addc0d10cd18cdbd 397 Gene3D G3DSA:1.20.140.10 234 395 5.3E-46 T 28-03-2018 CU254_RS12020 529ef16d621bdc50addc0d10cd18cdbd 397 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 245 393 1.8E-42 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS12020 529ef16d621bdc50addc0d10cd18cdbd 397 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 139 233 3.5E-24 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CU254_RS12020 529ef16d621bdc50addc0d10cd18cdbd 397 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 141 153 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CU254_RS12020 529ef16d621bdc50addc0d10cd18cdbd 397 Gene3D G3DSA:1.10.540.10 8 137 1.3E-32 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS12020 529ef16d621bdc50addc0d10cd18cdbd 397 Gene3D G3DSA:2.40.110.10 138 233 1.9E-36 T 28-03-2018 CU254_RS12020 529ef16d621bdc50addc0d10cd18cdbd 397 SUPERFAMILY SSF56645 16 254 6.81E-76 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS19995 9a2887fb760552cdd948ee22255c837d 468 Pfam PF00206 Lyase 12 344 4.3E-97 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal CU254_RS19995 9a2887fb760552cdd948ee22255c837d 468 SUPERFAMILY SSF48557 4 461 2.98E-138 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 CU254_RS19995 9a2887fb760552cdd948ee22255c837d 468 Gene3D G3DSA:1.20.200.10 140 416 4.3E-78 T 28-03-2018 CU254_RS19995 9a2887fb760552cdd948ee22255c837d 468 ProSitePatterns PS00163 Fumarate lyases signature. 319 328 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CU254_RS19995 9a2887fb760552cdd948ee22255c837d 468 Pfam PF10415 Fumarase C C-terminus 410 463 1.5E-13 T 28-03-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CU254_RS19995 9a2887fb760552cdd948ee22255c837d 468 PRINTS PR00145 Argininosuccinate lyase family signature 319 335 4.8E-6 T 28-03-2018 CU254_RS19995 9a2887fb760552cdd948ee22255c837d 468 PRINTS PR00145 Argininosuccinate lyase family signature 135 157 4.8E-6 T 28-03-2018 CU254_RS19995 9a2887fb760552cdd948ee22255c837d 468 PRINTS PR00145 Argininosuccinate lyase family signature 176 196 4.8E-6 T 28-03-2018 CU254_RS19995 9a2887fb760552cdd948ee22255c837d 468 Gene3D G3DSA:1.10.275.10 2 139 4.5E-51 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal CU254_RS19995 9a2887fb760552cdd948ee22255c837d 468 PRINTS PR00149 Fumarate lyase superfamily signature 181 199 1.0E-29 T 28-03-2018 IPR000362 Fumarate lyase family CU254_RS19995 9a2887fb760552cdd948ee22255c837d 468 PRINTS PR00149 Fumarate lyase superfamily signature 273 300 1.0E-29 T 28-03-2018 IPR000362 Fumarate lyase family CU254_RS19995 9a2887fb760552cdd948ee22255c837d 468 PRINTS PR00149 Fumarate lyase superfamily signature 319 335 1.0E-29 T 28-03-2018 IPR000362 Fumarate lyase family CU254_RS19995 9a2887fb760552cdd948ee22255c837d 468 PRINTS PR00149 Fumarate lyase superfamily signature 136 154 1.0E-29 T 28-03-2018 IPR000362 Fumarate lyase family CU254_RS19995 9a2887fb760552cdd948ee22255c837d 468 Gene3D G3DSA:1.10.40.30 417 463 5.8E-13 T 28-03-2018 CU254_RS39955 9a90f10edc4ae4f5346c086b0bad57d9 200 SUPERFAMILY SSF46689 3 76 6.67E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS39955 9a90f10edc4ae4f5346c086b0bad57d9 200 Gene3D G3DSA:1.10.357.10 59 198 1.9E-11 T 28-03-2018 CU254_RS39955 9a90f10edc4ae4f5346c086b0bad57d9 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 59 1.5E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS39955 9a90f10edc4ae4f5346c086b0bad57d9 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 2.7E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS39955 9a90f10edc4ae4f5346c086b0bad57d9 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 2.7E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS39955 9a90f10edc4ae4f5346c086b0bad57d9 200 Gene3D G3DSA:1.10.10.60 2 58 5.9E-16 T 28-03-2018 CU254_RS14580 a98fdb9b9c278bbd64a080b33dc44bd9 315 Gene3D G3DSA:3.40.1190.20 5 315 1.9E-79 T 28-03-2018 IPR029056 Ribokinase-like CU254_RS14580 a98fdb9b9c278bbd64a080b33dc44bd9 315 Pfam PF00294 pfkB family carbohydrate kinase 7 303 1.2E-50 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CU254_RS14580 a98fdb9b9c278bbd64a080b33dc44bd9 315 SUPERFAMILY SSF53613 5 310 4.52E-73 T 28-03-2018 IPR029056 Ribokinase-like CU254_RS14580 a98fdb9b9c278bbd64a080b33dc44bd9 315 TIGRFAM TIGR04382 myo_inos_iolC_N: 5-dehydro-2-deoxygluconokinase 5 308 3.4E-112 T 28-03-2018 IPR030830 5-Dehydro-2-deoxygluconokinase KEGG: 00562+2.7.1.92 CU254_RS34590 fecc879d5c222e7f4da9a45e820020be 381 Gene3D G3DSA:1.20.140.10 217 380 5.5E-55 T 28-03-2018 CU254_RS34590 fecc879d5c222e7f4da9a45e820020be 381 SUPERFAMILY SSF47203 226 379 8.05E-50 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS34590 fecc879d5c222e7f4da9a45e820020be 381 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 124 215 4.0E-23 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CU254_RS34590 fecc879d5c222e7f4da9a45e820020be 381 Gene3D G3DSA:2.40.110.10 123 216 7.1E-37 T 28-03-2018 CU254_RS34590 fecc879d5c222e7f4da9a45e820020be 381 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 126 138 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CU254_RS34590 fecc879d5c222e7f4da9a45e820020be 381 SUPERFAMILY SSF56645 4 239 2.36E-55 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS34590 fecc879d5c222e7f4da9a45e820020be 381 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 228 377 2.5E-48 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS34590 fecc879d5c222e7f4da9a45e820020be 381 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 120 5.1E-12 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS34590 fecc879d5c222e7f4da9a45e820020be 381 Gene3D G3DSA:1.10.540.10 1 122 8.0E-19 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS27535 74c534a16bdd67502a0ce6d5e0fe3b7f 132 Gene3D G3DSA:1.10.490.10 1 130 2.6E-34 T 28-03-2018 CU254_RS27535 74c534a16bdd67502a0ce6d5e0fe3b7f 132 SUPERFAMILY SSF46458 11 129 1.23E-36 T 28-03-2018 IPR009050 Globin-like CU254_RS27535 74c534a16bdd67502a0ce6d5e0fe3b7f 132 Pfam PF01152 Bacterial-like globin 11 128 4.8E-34 T 28-03-2018 IPR001486 Truncated hemoglobin GO:0019825 CU254_RS15355 df352d8bbfe46e26a8984a8c96909a1d 565 PIRSF PIRSF006060 8 489 8.1E-74 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CU254_RS15355 df352d8bbfe46e26a8984a8c96909a1d 565 PIRSF PIRSF006060 485 555 110.0 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CU254_RS15355 df352d8bbfe46e26a8984a8c96909a1d 565 Pfam PF13520 Amino acid permease 26 451 7.9E-43 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CU254_RS19860 78de5dae92a9d54c67c6eb8ff3573ba6 564 Gene3D G3DSA:3.40.50.1220 188 349 1.1E-50 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CU254_RS19860 78de5dae92a9d54c67c6eb8ff3573ba6 564 SUPERFAMILY SSF52518 2 174 6.79E-58 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS19860 78de5dae92a9d54c67c6eb8ff3573ba6 564 Gene3D G3DSA:3.40.50.970 1 187 6.2E-58 T 28-03-2018 CU254_RS19860 78de5dae92a9d54c67c6eb8ff3573ba6 564 Gene3D G3DSA:3.40.50.970 354 564 3.1E-38 T 28-03-2018 CU254_RS19860 78de5dae92a9d54c67c6eb8ff3573ba6 564 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 7 172 1.3E-59 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CU254_RS19860 78de5dae92a9d54c67c6eb8ff3573ba6 564 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 191 327 8.0E-39 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CU254_RS19860 78de5dae92a9d54c67c6eb8ff3573ba6 564 SUPERFAMILY SSF52467 155 357 5.39E-51 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CU254_RS19860 78de5dae92a9d54c67c6eb8ff3573ba6 564 SUPERFAMILY SSF52518 364 549 1.11E-47 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS19860 78de5dae92a9d54c67c6eb8ff3573ba6 564 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 388 540 1.1E-33 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CU254_RS35180 9a2e3b457ee8d25767355a998c50d6d6 183 Pfam PF01872 RibD C-terminal domain 5 177 2.6E-24 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CU254_RS35180 9a2e3b457ee8d25767355a998c50d6d6 183 Gene3D G3DSA:3.40.430.10 5 182 1.4E-38 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CU254_RS35180 9a2e3b457ee8d25767355a998c50d6d6 183 SUPERFAMILY SSF53597 6 182 1.31E-32 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CU254_RS26760 2f06b0d49646161d876c465f6d002553 135 SUPERFAMILY SSF81301 7 118 3.76E-38 T 28-03-2018 CU254_RS26760 2f06b0d49646161d876c465f6d002553 135 Gene3D G3DSA:3.30.460.10 4 112 2.2E-31 T 28-03-2018 CU254_RS26760 2f06b0d49646161d876c465f6d002553 135 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 4 109 22.77 T 28-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS CU254_RS26760 2f06b0d49646161d876c465f6d002553 135 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 14 108 1.6E-31 T 28-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS CU254_RS26760 2f06b0d49646161d876c465f6d002553 135 Pfam PF02410 Ribosomal silencing factor during starvation 15 108 6.2E-24 T 28-03-2018 CU254_RS03665 722bd7d4b1d271d1e23cc2fd8c5fa82c 224 SUPERFAMILY SSF69593 9 218 4.84E-45 T 28-03-2018 CU254_RS03665 722bd7d4b1d271d1e23cc2fd8c5fa82c 224 SMART SM00563 34 153 2.1E-27 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CU254_RS03665 722bd7d4b1d271d1e23cc2fd8c5fa82c 224 Pfam PF01553 Acyltransferase 20 149 4.9E-21 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CU254_RS03665 722bd7d4b1d271d1e23cc2fd8c5fa82c 224 Gene3D G3DSA:3.40.1130.10 13 224 4.6E-49 T 28-03-2018 CU254_RS14915 694de1ab6ffe92b3826a4bbab89a1dbb 334 SUPERFAMILY SSF53686 8 333 3.57E-82 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CU254_RS14915 694de1ab6ffe92b3826a4bbab89a1dbb 334 Gene3D G3DSA:3.40.50.1100 57 154 1.4E-33 T 28-03-2018 CU254_RS14915 694de1ab6ffe92b3826a4bbab89a1dbb 334 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 16 321 7.9E-55 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CU254_RS14915 694de1ab6ffe92b3826a4bbab89a1dbb 334 Gene3D G3DSA:3.40.50.1100 155 334 2.3E-27 T 28-03-2018 CU254_RS14915 694de1ab6ffe92b3826a4bbab89a1dbb 334 PIRSF PIRSF006278 2 334 2.2E-104 T 28-03-2018 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase CU254_RS14915 694de1ab6ffe92b3826a4bbab89a1dbb 334 TIGRFAM TIGR01275 ACC_deam_rel: pyridoxal phosphate-dependent enzymes, D-cysteine desulfhydrase family 15 330 1.5E-92 T 28-03-2018 IPR005966 D-cysteine desulfhydrase GO:0003824 KEGG: 00270+4.4.1.15 CU254_RS05500 97d80fbb65b950961211ab09e7f184f7 135 SUPERFAMILY SSF54593 7 133 1.65E-16 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS05500 97d80fbb65b950961211ab09e7f184f7 135 Gene3D G3DSA:3.10.180.10 2 135 8.2E-18 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS05500 97d80fbb65b950961211ab09e7f184f7 135 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 117 2.1E-14 T 28-03-2018 CU254_RS08560 5316ade22b65a3baf1f8b530ff56b605 327 SUPERFAMILY SSF53901 12 324 6.03E-61 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS08560 5316ade22b65a3baf1f8b530ff56b605 327 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 16 323 5.0E-96 T 28-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CU254_RS08560 5316ade22b65a3baf1f8b530ff56b605 327 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 14 326 57.409 T 28-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CU254_RS08560 5316ade22b65a3baf1f8b530ff56b605 327 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 233 324 1.4E-27 T 28-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CU254_RS08560 5316ade22b65a3baf1f8b530ff56b605 327 Gene3D G3DSA:3.40.47.10 174 325 1.1E-32 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS08560 5316ade22b65a3baf1f8b530ff56b605 327 Gene3D G3DSA:3.40.47.10 9 173 1.3E-35 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS08560 5316ade22b65a3baf1f8b530ff56b605 327 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 119 195 8.1E-27 T 28-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CU254_RS23875 9ac67085daeda6672421dc86e019ae8e 198 Pfam PF13305 WHG domain 92 172 1.3E-11 T 28-03-2018 IPR025996 WHG domain CU254_RS23875 9ac67085daeda6672421dc86e019ae8e 198 SUPERFAMILY SSF46689 8 81 2.46E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS23875 9ac67085daeda6672421dc86e019ae8e 198 Gene3D G3DSA:1.10.10.60 14 66 9.1E-15 T 28-03-2018 CU254_RS23875 9ac67085daeda6672421dc86e019ae8e 198 SUPERFAMILY SSF48498 89 194 1.2E-10 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS23875 9ac67085daeda6672421dc86e019ae8e 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 65 1.6E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS23875 9ac67085daeda6672421dc86e019ae8e 198 Gene3D G3DSA:1.10.357.10 67 198 3.0E-21 T 28-03-2018 CU254_RS03610 78c34b6ad93591fe031def76ba69df06 206 Gene3D G3DSA:1.10.357.10 65 206 2.4E-15 T 28-03-2018 CU254_RS03610 78c34b6ad93591fe031def76ba69df06 206 Gene3D G3DSA:1.10.10.60 2 64 7.4E-18 T 28-03-2018 CU254_RS03610 78c34b6ad93591fe031def76ba69df06 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 1.2E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS03610 78c34b6ad93591fe031def76ba69df06 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 1.2E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS03610 78c34b6ad93591fe031def76ba69df06 206 SUPERFAMILY SSF48498 84 200 3.92E-11 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS03610 78c34b6ad93591fe031def76ba69df06 206 SUPERFAMILY SSF46689 4 70 2.41E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS03610 78c34b6ad93591fe031def76ba69df06 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 63 3.8E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS33980 f0b4a680ec84021caa70be67c2c246b7 261 Gene3D G3DSA:3.40.50.1110 2 194 5.2E-31 T 28-03-2018 CU254_RS33980 f0b4a680ec84021caa70be67c2c246b7 261 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 8 180 5.8E-26 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CU254_RS33980 f0b4a680ec84021caa70be67c2c246b7 261 SUPERFAMILY SSF52266 5 191 3.5E-31 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CU254_RS12505 85f051bd96ac87d63d518b319f173d94 205 ProSitePatterns PS00622 LuxR-type HTH domain signature. 157 184 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS12505 85f051bd96ac87d63d518b319f173d94 205 Pfam PF00072 Response regulator receiver domain 5 114 8.5E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS12505 85f051bd96ac87d63d518b319f173d94 205 SUPERFAMILY SSF46894 129 203 1.02E-20 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS12505 85f051bd96ac87d63d518b319f173d94 205 SUPERFAMILY SSF52172 1 134 4.27E-27 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS12505 85f051bd96ac87d63d518b319f173d94 205 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 173 3.6E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS12505 85f051bd96ac87d63d518b319f173d94 205 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 143 157 3.6E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS12505 85f051bd96ac87d63d518b319f173d94 205 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 185 3.6E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS12505 85f051bd96ac87d63d518b319f173d94 205 Pfam PF00196 Bacterial regulatory proteins, luxR family 142 194 8.5E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS12505 85f051bd96ac87d63d518b319f173d94 205 Gene3D G3DSA:3.40.50.2300 1 125 2.3E-31 T 28-03-2018 CU254_RS12505 85f051bd96ac87d63d518b319f173d94 205 SMART SM00448 2 114 1.0E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS12505 85f051bd96ac87d63d518b319f173d94 205 SMART SM00421 140 197 2.2E-22 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS12505 85f051bd96ac87d63d518b319f173d94 205 Gene3D G3DSA:1.10.10.10 126 205 1.2E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS30880 9de27c3a672b0e0999594c6db3c7ac76 196 Pfam PF01872 RibD C-terminal domain 5 182 3.3E-19 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CU254_RS30880 9de27c3a672b0e0999594c6db3c7ac76 196 SUPERFAMILY SSF53597 4 192 1.06E-20 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CU254_RS30880 9de27c3a672b0e0999594c6db3c7ac76 196 Gene3D G3DSA:3.40.430.10 4 192 6.0E-28 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CU254_RS14565 921ba8e05c9b62efb491e40cc365a030 619 TIGRFAM TIGR04377 myo_inos_iolD: 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase 2 616 1.7E-279 T 28-03-2018 IPR030817 3,5/4-Trihydroxycyclohexa-1,2-dione hydrolase GO:0016823|GO:0019310|GO:0030976 KEGG: 00562+3.7.1.22 CU254_RS14565 921ba8e05c9b62efb491e40cc365a030 619 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 451 470 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CU254_RS14565 921ba8e05c9b62efb491e40cc365a030 619 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 218 352 7.3E-35 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CU254_RS14565 921ba8e05c9b62efb491e40cc365a030 619 SUPERFAMILY SSF52518 2 208 1.77E-28 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS14565 921ba8e05c9b62efb491e40cc365a030 619 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 415 573 7.4E-35 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CU254_RS14565 921ba8e05c9b62efb491e40cc365a030 619 SUPERFAMILY SSF52518 395 607 3.46E-48 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS14565 921ba8e05c9b62efb491e40cc365a030 619 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 198 2.6E-33 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CU254_RS14565 921ba8e05c9b62efb491e40cc365a030 619 Gene3D G3DSA:3.40.50.1220 210 379 1.2E-42 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CU254_RS14565 921ba8e05c9b62efb491e40cc365a030 619 Gene3D G3DSA:3.40.50.970 388 603 9.0E-37 T 28-03-2018 CU254_RS14565 921ba8e05c9b62efb491e40cc365a030 619 SUPERFAMILY SSF52467 185 369 4.04E-46 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CU254_RS14565 921ba8e05c9b62efb491e40cc365a030 619 Gene3D G3DSA:3.40.50.970 1 209 9.7E-43 T 28-03-2018 CU254_RS02170 43c54f5d139d51f8a457b051e7bf0cca 667 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 337 351 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CU254_RS02170 43c54f5d139d51f8a457b051e7bf0cca 667 PRINTS PR00301 70kDa heat shock protein signature 54 62 2.3E-11 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CU254_RS02170 43c54f5d139d51f8a457b051e7bf0cca 667 PRINTS PR00301 70kDa heat shock protein signature 364 384 2.3E-11 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CU254_RS02170 43c54f5d139d51f8a457b051e7bf0cca 667 PRINTS PR00301 70kDa heat shock protein signature 334 350 2.3E-11 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CU254_RS02170 43c54f5d139d51f8a457b051e7bf0cca 667 PRINTS PR00301 70kDa heat shock protein signature 3 16 2.3E-11 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CU254_RS02170 43c54f5d139d51f8a457b051e7bf0cca 667 PRINTS PR00301 70kDa heat shock protein signature 187 197 2.3E-11 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CU254_RS02170 43c54f5d139d51f8a457b051e7bf0cca 667 Gene3D G3DSA:3.30.420.40 187 365 7.3E-28 T 28-03-2018 CU254_RS02170 43c54f5d139d51f8a457b051e7bf0cca 667 Gene3D G3DSA:3.30.420.40 1 186 3.1E-25 T 28-03-2018 CU254_RS02170 43c54f5d139d51f8a457b051e7bf0cca 667 Pfam PF00012 Hsp70 protein 177 383 2.9E-25 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CU254_RS02170 43c54f5d139d51f8a457b051e7bf0cca 667 TIGRFAM TIGR03931 T7SS_Rv3446c: type VII secretion-associated protein, Rv3446c family 520 665 6.7E-19 T 28-03-2018 IPR023840 Type VII secretion system Rv3446c CU254_RS02170 43c54f5d139d51f8a457b051e7bf0cca 667 SUPERFAMILY SSF53067 176 377 4.03E-33 T 28-03-2018 CU254_RS02170 43c54f5d139d51f8a457b051e7bf0cca 667 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 181 194 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CU254_RS02170 43c54f5d139d51f8a457b051e7bf0cca 667 SUPERFAMILY SSF53067 4 155 2.79E-20 T 28-03-2018 CU254_RS06720 6613490bbd1977e5f5b5aefe80f51836 319 SUPERFAMILY SSF52402 4 178 1.4E-41 T 28-03-2018 CU254_RS06720 6613490bbd1977e5f5b5aefe80f51836 319 Gene3D G3DSA:3.40.50.620 1 186 3.5E-37 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS06720 6613490bbd1977e5f5b5aefe80f51836 319 PIRSF PIRSF000089 1 319 3.7E-101 T 28-03-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 CU254_RS06720 6613490bbd1977e5f5b5aefe80f51836 319 SUPERFAMILY SSF52467 192 313 9.81E-47 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CU254_RS06720 6613490bbd1977e5f5b5aefe80f51836 319 Gene3D G3DSA:3.40.50.1220 191 319 1.1E-58 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CU254_RS06720 6613490bbd1977e5f5b5aefe80f51836 319 Pfam PF01012 Electron transfer flavoprotein domain 4 175 1.1E-34 T 28-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CU254_RS06720 6613490bbd1977e5f5b5aefe80f51836 319 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 195 277 4.3E-36 T 28-03-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 CU254_RS06720 6613490bbd1977e5f5b5aefe80f51836 319 SMART SM00893 4 187 3.5E-30 T 28-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CU254_RS06720 6613490bbd1977e5f5b5aefe80f51836 319 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 258 284 - T 28-03-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 CU254_RS17435 dfd97cd4d4c631680d91d22fc89383ff 289 Gene3D G3DSA:3.40.50.720 5 152 1.7E-9 T 28-03-2018 CU254_RS17435 dfd97cd4d4c631680d91d22fc89383ff 289 SUPERFAMILY SSF51735 4 285 2.34E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS17435 dfd97cd4d4c631680d91d22fc89383ff 289 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 209 1.1E-27 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CU254_RS17435 dfd97cd4d4c631680d91d22fc89383ff 289 Gene3D G3DSA:3.90.25.10 153 288 3.4E-23 T 28-03-2018 CU254_RS06295 6ada6868c3eb7eb5cb739602622b62fc 175 TIGRFAM TIGR02159 PA_CoA_Oxy4: phenylacetate-CoA oxygenase, PaaJ subunit 23 175 7.6E-57 T 28-03-2018 IPR011883 Phenylacetate-CoA oxygenase, PaaJ subunit CU254_RS06295 6ada6868c3eb7eb5cb739602622b62fc 175 Pfam PF01883 Iron-sulfur cluster assembly protein 21 75 1.2E-15 T 28-03-2018 IPR002744 MIP18 family-like CU254_RS06295 6ada6868c3eb7eb5cb739602622b62fc 175 SUPERFAMILY SSF117916 15 105 8.07E-22 T 28-03-2018 IPR034904 Fe-S cluster assembly domain CU254_RS06295 6ada6868c3eb7eb5cb739602622b62fc 175 Gene3D G3DSA:3.30.300.130 10 107 6.5E-20 T 28-03-2018 IPR034904 Fe-S cluster assembly domain CU254_RS39260 abc6716fb40f0c97c318fbe0e93271d3 655 Pfam PF00204 DNA gyrase B 236 405 1.4E-61 T 28-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CU254_RS39260 abc6716fb40f0c97c318fbe0e93271d3 655 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 8 655 4.2E-286 T 28-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CU254_RS39260 abc6716fb40f0c97c318fbe0e93271d3 655 SMART SM00387 33 176 1.2E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS39260 abc6716fb40f0c97c318fbe0e93271d3 655 ProSitePatterns PS00177 DNA topoisomerase II signature. 437 445 - T 28-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CU254_RS39260 abc6716fb40f0c97c318fbe0e93271d3 655 Gene3D G3DSA:3.30.565.10 18 239 3.5E-69 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS39260 abc6716fb40f0c97c318fbe0e93271d3 655 PRINTS PR01159 DNA gyrase subunit B signature 235 257 5.6E-73 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CU254_RS39260 abc6716fb40f0c97c318fbe0e93271d3 655 PRINTS PR01159 DNA gyrase subunit B signature 485 494 5.6E-73 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CU254_RS39260 abc6716fb40f0c97c318fbe0e93271d3 655 PRINTS PR01159 DNA gyrase subunit B signature 389 409 5.6E-73 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CU254_RS39260 abc6716fb40f0c97c318fbe0e93271d3 655 PRINTS PR01159 DNA gyrase subunit B signature 608 620 5.6E-73 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CU254_RS39260 abc6716fb40f0c97c318fbe0e93271d3 655 PRINTS PR01159 DNA gyrase subunit B signature 181 196 5.6E-73 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CU254_RS39260 abc6716fb40f0c97c318fbe0e93271d3 655 PRINTS PR01159 DNA gyrase subunit B signature 375 389 5.6E-73 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CU254_RS39260 abc6716fb40f0c97c318fbe0e93271d3 655 PRINTS PR01159 DNA gyrase subunit B signature 196 209 5.6E-73 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CU254_RS39260 abc6716fb40f0c97c318fbe0e93271d3 655 PRINTS PR01159 DNA gyrase subunit B signature 624 640 5.6E-73 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CU254_RS39260 abc6716fb40f0c97c318fbe0e93271d3 655 PRINTS PR01159 DNA gyrase subunit B signature 327 343 5.6E-73 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CU254_RS39260 abc6716fb40f0c97c318fbe0e93271d3 655 PRINTS PR01159 DNA gyrase subunit B signature 8 18 5.6E-73 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CU254_RS39260 abc6716fb40f0c97c318fbe0e93271d3 655 SUPERFAMILY SSF55874 7 213 4.45E-69 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS39260 abc6716fb40f0c97c318fbe0e93271d3 655 Gene3D G3DSA:3.40.50.670 417 652 1.4E-94 T 28-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CU254_RS39260 abc6716fb40f0c97c318fbe0e93271d3 655 SMART SM00433 37 648 0.0 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CU254_RS39260 abc6716fb40f0c97c318fbe0e93271d3 655 SUPERFAMILY SSF54211 236 406 4.74E-59 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CU254_RS39260 abc6716fb40f0c97c318fbe0e93271d3 655 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 586 643 3.9E-27 T 28-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 CU254_RS39260 abc6716fb40f0c97c318fbe0e93271d3 655 SUPERFAMILY SSF56719 409 650 2.07E-81 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CU254_RS39260 abc6716fb40f0c97c318fbe0e93271d3 655 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 5 655 91.311 T 28-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CU254_RS39260 abc6716fb40f0c97c318fbe0e93271d3 655 PRINTS PR00418 DNA topoisomerase II family signature 501 517 1.1E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CU254_RS39260 abc6716fb40f0c97c318fbe0e93271d3 655 PRINTS PR00418 DNA topoisomerase II family signature 539 551 1.1E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CU254_RS39260 abc6716fb40f0c97c318fbe0e93271d3 655 PRINTS PR00418 DNA topoisomerase II family signature 283 296 1.1E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CU254_RS39260 abc6716fb40f0c97c318fbe0e93271d3 655 PRINTS PR00418 DNA topoisomerase II family signature 115 129 1.1E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CU254_RS39260 abc6716fb40f0c97c318fbe0e93271d3 655 PRINTS PR00418 DNA topoisomerase II family signature 435 449 1.1E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CU254_RS39260 abc6716fb40f0c97c318fbe0e93271d3 655 PRINTS PR00418 DNA topoisomerase II family signature 587 603 1.1E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CU254_RS39260 abc6716fb40f0c97c318fbe0e93271d3 655 PRINTS PR00418 DNA topoisomerase II family signature 72 85 1.1E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CU254_RS39260 abc6716fb40f0c97c318fbe0e93271d3 655 PRINTS PR00418 DNA topoisomerase II family signature 519 536 1.1E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CU254_RS39260 abc6716fb40f0c97c318fbe0e93271d3 655 PRINTS PR00418 DNA topoisomerase II family signature 37 52 1.1E-68 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CU254_RS39260 abc6716fb40f0c97c318fbe0e93271d3 655 Gene3D G3DSA:3.30.230.10 240 407 4.9E-63 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CU254_RS39260 abc6716fb40f0c97c318fbe0e93271d3 655 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 35 173 1.1E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS39260 abc6716fb40f0c97c318fbe0e93271d3 655 Pfam PF01751 Toprim domain 434 544 4.6E-16 T 28-03-2018 IPR006171 TOPRIM domain CU254_RS04645 b08b2ddd7d3fa0ef6ef45cd511fd774f 306 Pfam PF08924 Domain of unknown function (DUF1906) 12 133 3.3E-10 T 28-03-2018 IPR015020 Protein of unknown function DUF1906 CU254_RS04645 b08b2ddd7d3fa0ef6ef45cd511fd774f 306 Gene3D G3DSA:3.20.20.80 10 192 1.2E-11 T 28-03-2018 CU254_RS04645 b08b2ddd7d3fa0ef6ef45cd511fd774f 306 SUPERFAMILY SSF51445 17 156 5.69E-5 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS08250 15e710eb9ca6a4778b608062cd5202e1 193 SUPERFAMILY SSF63817 48 190 2.62E-15 T 28-03-2018 IPR023365 Sortase domain CU254_RS08250 15e710eb9ca6a4778b608062cd5202e1 193 Pfam PF04203 Sortase family 51 191 1.3E-17 T 28-03-2018 IPR005754 Sortase family CU254_RS08250 15e710eb9ca6a4778b608062cd5202e1 193 Gene3D G3DSA:2.40.260.10 25 193 2.5E-23 T 28-03-2018 IPR023365 Sortase domain CU254_RS41015 78580344f6db1800917c4a624dd2c641 310 SUPERFAMILY SSF51658 12 295 3.8E-41 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CU254_RS41015 78580344f6db1800917c4a624dd2c641 310 Gene3D G3DSA:3.20.20.150 1 302 1.5E-44 T 28-03-2018 CU254_RS41015 78580344f6db1800917c4a624dd2c641 310 Pfam PF01261 Xylose isomerase-like TIM barrel 27 234 7.4E-24 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CU254_RS21485 7c72eaf3a7511155ed1be7e6559e3a9b 200 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 3 153 2.0E-33 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CU254_RS21485 7c72eaf3a7511155ed1be7e6559e3a9b 200 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 1 155 45.524 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CU254_RS21485 7c72eaf3a7511155ed1be7e6559e3a9b 200 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 114 149 - T 28-03-2018 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 CU254_RS21485 7c72eaf3a7511155ed1be7e6559e3a9b 200 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 3 152 1.6E-57 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CU254_RS21485 7c72eaf3a7511155ed1be7e6559e3a9b 200 SUPERFAMILY SSF53098 2 156 6.83E-45 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS21485 7c72eaf3a7511155ed1be7e6559e3a9b 200 Gene3D G3DSA:3.30.420.10 1 161 1.5E-48 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS21485 7c72eaf3a7511155ed1be7e6559e3a9b 200 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 140 152 6.8E-39 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CU254_RS21485 7c72eaf3a7511155ed1be7e6559e3a9b 200 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 84 100 6.8E-39 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CU254_RS21485 7c72eaf3a7511155ed1be7e6559e3a9b 200 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 4 17 6.8E-39 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CU254_RS21485 7c72eaf3a7511155ed1be7e6559e3a9b 200 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 62 78 6.8E-39 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CU254_RS21485 7c72eaf3a7511155ed1be7e6559e3a9b 200 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 108 127 6.8E-39 T 28-03-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 CU254_RS01290 d282fc0e34df435ab8b7e3301595b23f 505 Gene3D G3DSA:1.10.390.10 311 462 3.1E-33 T 28-03-2018 CU254_RS01290 d282fc0e34df435ab8b7e3301595b23f 505 SUPERFAMILY SSF55486 254 467 1.61E-46 T 28-03-2018 CU254_RS01290 d282fc0e34df435ab8b7e3301595b23f 505 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 165 180 5.7E-14 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CU254_RS01290 d282fc0e34df435ab8b7e3301595b23f 505 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 213 228 5.7E-14 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CU254_RS01290 d282fc0e34df435ab8b7e3301595b23f 505 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 337 349 5.7E-14 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CU254_RS01290 d282fc0e34df435ab8b7e3301595b23f 505 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 318 333 5.7E-14 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CU254_RS01290 d282fc0e34df435ab8b7e3301595b23f 505 Gene3D G3DSA:2.60.40.1730 46 231 8.4E-40 T 28-03-2018 CU254_RS01290 d282fc0e34df435ab8b7e3301595b23f 505 SUPERFAMILY SSF63737 35 229 1.44E-36 T 28-03-2018 CU254_RS01290 d282fc0e34df435ab8b7e3301595b23f 505 Pfam PF01433 Peptidase family M1 domain 314 458 2.6E-27 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CU254_RS22795 3bdff65b7519165fe5d712cea1056878 245 PIRSF PIRSF006648 4 245 1.5E-20 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CU254_RS22795 3bdff65b7519165fe5d712cea1056878 245 Pfam PF01061 ABC-2 type transporter 5 212 4.4E-25 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CU254_RS24250 7f544af60dac07cff8263c9e6e3b884e 352 Gene3D G3DSA:3.30.70.360 127 233 3.7E-13 T 28-03-2018 CU254_RS24250 7f544af60dac07cff8263c9e6e3b884e 352 Pfam PF07687 Peptidase dimerisation domain 140 219 6.9E-5 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CU254_RS24250 7f544af60dac07cff8263c9e6e3b884e 352 SUPERFAMILY SSF53187 240 334 3.52E-7 T 28-03-2018 CU254_RS24250 7f544af60dac07cff8263c9e6e3b884e 352 SUPERFAMILY SSF53187 47 143 3.52E-7 T 28-03-2018 CU254_RS24250 7f544af60dac07cff8263c9e6e3b884e 352 SUPERFAMILY SSF55031 130 233 1.11E-14 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CU254_RS15935 3b933f758274e03372d3adb2090e63c4 536 Gene3D G3DSA:3.20.20.140 202 478 1.4E-51 T 28-03-2018 CU254_RS15935 3b933f758274e03372d3adb2090e63c4 536 Gene3D G3DSA:2.30.40.10 7 115 7.1E-12 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS15935 3b933f758274e03372d3adb2090e63c4 536 SUPERFAMILY SSF51556 208 493 4.09E-33 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS15935 3b933f758274e03372d3adb2090e63c4 536 SUPERFAMILY SSF51556 61 124 4.09E-33 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS15935 3b933f758274e03372d3adb2090e63c4 536 SUPERFAMILY SSF51338 8 76 1.8E-13 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS15935 3b933f758274e03372d3adb2090e63c4 536 Gene3D G3DSA:2.30.40.10 479 536 3.6E-9 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS15935 3b933f758274e03372d3adb2090e63c4 536 Pfam PF07969 Amidohydrolase family 53 533 1.9E-95 T 28-03-2018 IPR013108 Amidohydrolase 3 CU254_RS06040 4a98ca63c56995fb02a753596112fa56 101 Gene3D G3DSA:1.10.10.10 8 98 3.3E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS06040 4a98ca63c56995fb02a753596112fa56 101 Pfam PF13601 Winged helix DNA-binding domain 22 97 1.9E-24 T 28-03-2018 IPR027395 Winged helix DNA-binding domain CU254_RS06040 4a98ca63c56995fb02a753596112fa56 101 SUPERFAMILY SSF46785 25 96 2.0E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS30110 f04138550ea17ddaf088b4c552cfb5b3 55 Pfam PF00196 Bacterial regulatory proteins, luxR family 9 53 4.7E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS30110 f04138550ea17ddaf088b4c552cfb5b3 55 SUPERFAMILY SSF46894 8 53 1.02E-10 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS30110 f04138550ea17ddaf088b4c552cfb5b3 55 Gene3D G3DSA:1.10.10.10 3 55 2.0E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS30110 f04138550ea17ddaf088b4c552cfb5b3 55 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 24 40 1.6E-6 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS30110 f04138550ea17ddaf088b4c552cfb5b3 55 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 10 24 1.6E-6 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS30110 f04138550ea17ddaf088b4c552cfb5b3 55 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 40 52 1.6E-6 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS30110 f04138550ea17ddaf088b4c552cfb5b3 55 SMART SM00421 7 55 0.0043 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS37665 ed827c8a35fb3a6e25ea93b526662e35 449 Gene3D G3DSA:2.140.10.10 49 232 3.3E-15 T 28-03-2018 CU254_RS37665 ed827c8a35fb3a6e25ea93b526662e35 449 Gene3D G3DSA:2.140.10.10 233 437 2.9E-11 T 28-03-2018 CU254_RS37665 ed827c8a35fb3a6e25ea93b526662e35 449 SUPERFAMILY SSF50998 309 426 2.82E-8 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CU254_RS37665 ed827c8a35fb3a6e25ea93b526662e35 449 SUPERFAMILY SSF50998 232 258 2.82E-8 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CU254_RS37665 ed827c8a35fb3a6e25ea93b526662e35 449 SUPERFAMILY SSF50998 69 249 2.49E-13 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CU254_RS37665 ed827c8a35fb3a6e25ea93b526662e35 449 Pfam PF13360 PQQ-like domain 66 243 6.1E-12 T 28-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat CU254_RS37665 ed827c8a35fb3a6e25ea93b526662e35 449 Pfam PF13360 PQQ-like domain 315 398 1.8E-4 T 28-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat CU254_RS34090 3f9bfd8c7bbc3c196b6a44c319dea080 1465 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 645 686 2.2E-6 T 28-03-2018 IPR006530 YD repeat CU254_RS34090 3f9bfd8c7bbc3c196b6a44c319dea080 1465 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 604 643 2.9E-6 T 28-03-2018 IPR006530 YD repeat CU254_RS34090 3f9bfd8c7bbc3c196b6a44c319dea080 1465 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 876 916 4.1E-9 T 28-03-2018 IPR006530 YD repeat CU254_RS34090 3f9bfd8c7bbc3c196b6a44c319dea080 1465 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 751 790 1.0E-5 T 28-03-2018 IPR006530 YD repeat CU254_RS34090 3f9bfd8c7bbc3c196b6a44c319dea080 1465 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 709 748 4.5E-6 T 28-03-2018 IPR006530 YD repeat CU254_RS34090 3f9bfd8c7bbc3c196b6a44c319dea080 1465 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 978 1007 9.9E-6 T 28-03-2018 IPR006530 YD repeat CU254_RS34090 3f9bfd8c7bbc3c196b6a44c319dea080 1465 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 518 553 8.4E-4 T 28-03-2018 IPR006530 YD repeat CU254_RS34090 3f9bfd8c7bbc3c196b6a44c319dea080 1465 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1160 1192 1.3E-5 T 28-03-2018 IPR006530 YD repeat CU254_RS34090 3f9bfd8c7bbc3c196b6a44c319dea080 1465 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 687 726 1.1E-7 T 28-03-2018 IPR006530 YD repeat CU254_RS34090 3f9bfd8c7bbc3c196b6a44c319dea080 1465 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 834 875 5.1E-9 T 28-03-2018 IPR006530 YD repeat CU254_RS34090 3f9bfd8c7bbc3c196b6a44c319dea080 1465 Gene3D G3DSA:1.10.287.850 78 162 5.9E-9 T 28-03-2018 CU254_RS34090 3f9bfd8c7bbc3c196b6a44c319dea080 1465 Gene3D G3DSA:2.130.10.10 820 1236 0.0069 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CU254_RS34090 3f9bfd8c7bbc3c196b6a44c319dea080 1465 SUPERFAMILY SSF140453 86 156 8.37E-5 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CU254_RS34090 3f9bfd8c7bbc3c196b6a44c319dea080 1465 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1284 1357 2.7E-22 T 28-03-2018 IPR022385 Rhs repeat-associated core GO:0097264 CU254_RS34090 3f9bfd8c7bbc3c196b6a44c319dea080 1465 SUPERFAMILY SSF69304 1085 1235 1.05E-7 T 28-03-2018 CU254_RS34090 3f9bfd8c7bbc3c196b6a44c319dea080 1465 SUPERFAMILY SSF69304 947 1022 1.05E-7 T 28-03-2018 CU254_RS34090 3f9bfd8c7bbc3c196b6a44c319dea080 1465 SUPERFAMILY SSF50960 391 659 5.75E-6 T 28-03-2018 CU254_RS34090 3f9bfd8c7bbc3c196b6a44c319dea080 1465 Gene3D G3DSA:2.130.10.10 377 633 0.077 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CU254_RS34090 3f9bfd8c7bbc3c196b6a44c319dea080 1465 Pfam PF05593 RHS Repeat 855 892 3.4E-9 T 28-03-2018 IPR031325 RHS repeat CU254_RS34090 3f9bfd8c7bbc3c196b6a44c319dea080 1465 Pfam PF05593 RHS Repeat 674 702 2.4E-7 T 28-03-2018 IPR031325 RHS repeat CU254_RS34090 3f9bfd8c7bbc3c196b6a44c319dea080 1465 Pfam PF05593 RHS Repeat 624 660 3.4E-8 T 28-03-2018 IPR031325 RHS repeat CU254_RS34090 3f9bfd8c7bbc3c196b6a44c319dea080 1465 Pfam PF05593 RHS Repeat 518 553 8.7E-5 T 28-03-2018 IPR031325 RHS repeat CU254_RS34090 3f9bfd8c7bbc3c196b6a44c319dea080 1465 Pfam PF05593 RHS Repeat 709 744 4.5E-5 T 28-03-2018 IPR031325 RHS repeat CU254_RS34090 3f9bfd8c7bbc3c196b6a44c319dea080 1465 Pfam PF05593 RHS Repeat 539 574 3.1E-5 T 28-03-2018 IPR031325 RHS repeat CU254_RS34090 3f9bfd8c7bbc3c196b6a44c319dea080 1465 Pfam PF05593 RHS Repeat 1160 1189 1.2E-5 T 28-03-2018 IPR031325 RHS repeat CU254_RS31050 19943db9e4b5b6679d62e3893dda27e7 257 Gene3D G3DSA:3.40.1490.10 154 257 4.4E-17 T 28-03-2018 IPR023476 Peptidyl-tRNA hydrolase II domain MetaCyc: PWY-6308 CU254_RS31050 19943db9e4b5b6679d62e3893dda27e7 257 Pfam PF01981 Peptidyl-tRNA hydrolase PTH2 159 255 2.4E-8 T 28-03-2018 IPR002833 Peptidyl-tRNA hydrolase, PTH2 GO:0004045 MetaCyc: PWY-6308 CU254_RS31050 19943db9e4b5b6679d62e3893dda27e7 257 SUPERFAMILY SSF102462 157 255 2.27E-17 T 28-03-2018 IPR023476 Peptidyl-tRNA hydrolase II domain MetaCyc: PWY-6308 CU254_RS33260 4f88b82aad1622e53ac098bc5c94b401 125 SUPERFAMILY SSF46785 14 122 7.75E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS33260 4f88b82aad1622e53ac098bc5c94b401 125 Gene3D G3DSA:1.10.10.10 14 76 4.3E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS33260 4f88b82aad1622e53ac098bc5c94b401 125 Pfam PF03965 Penicillinase repressor 14 122 1.8E-25 T 28-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 CU254_RS08270 fb1923535a51f0c54d3b1918c47f7026 588 Pfam PF07690 Major Facilitator Superfamily 26 439 7.9E-36 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS08270 fb1923535a51f0c54d3b1918c47f7026 588 Gene3D G3DSA:1.20.1250.20 281 569 2.9E-25 T 28-03-2018 CU254_RS08270 fb1923535a51f0c54d3b1918c47f7026 588 Gene3D G3DSA:1.20.1250.20 2 217 2.6E-22 T 28-03-2018 CU254_RS08270 fb1923535a51f0c54d3b1918c47f7026 588 SUPERFAMILY SSF103473 530 558 3.84E-49 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS08270 fb1923535a51f0c54d3b1918c47f7026 588 SUPERFAMILY SSF103473 17 219 3.84E-49 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS08270 fb1923535a51f0c54d3b1918c47f7026 588 SUPERFAMILY SSF103473 271 449 3.84E-49 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS23325 68fb98930ee703b2e331f86f5cf170df 397 SUPERFAMILY SSF52777 3 153 8.67E-21 T 28-03-2018 CU254_RS23325 68fb98930ee703b2e331f86f5cf170df 397 SUPERFAMILY SSF52777 165 312 5.11E-14 T 28-03-2018 CU254_RS23325 68fb98930ee703b2e331f86f5cf170df 397 Gene3D G3DSA:3.30.559.10 2 170 1.7E-19 T 28-03-2018 CU254_RS23325 68fb98930ee703b2e331f86f5cf170df 397 Pfam PF00668 Condensation domain 20 61 8.0E-5 T 28-03-2018 IPR001242 Condensation domain CU254_RS23325 68fb98930ee703b2e331f86f5cf170df 397 Pfam PF00668 Condensation domain 105 302 1.7E-13 T 28-03-2018 IPR001242 Condensation domain CU254_RS23510 8584ac7eeed5acb771cacd72f3a8ec70 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 8.4E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS23510 8584ac7eeed5acb771cacd72f3a8ec70 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 8.4E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS23510 8584ac7eeed5acb771cacd72f3a8ec70 196 Gene3D G3DSA:1.10.357.10 72 193 6.0E-23 T 28-03-2018 CU254_RS23510 8584ac7eeed5acb771cacd72f3a8ec70 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 67 2.7E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS23510 8584ac7eeed5acb771cacd72f3a8ec70 196 Gene3D G3DSA:1.10.10.60 7 71 1.7E-19 T 28-03-2018 CU254_RS23510 8584ac7eeed5acb771cacd72f3a8ec70 196 SUPERFAMILY SSF46689 8 81 6.67E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS10150 1d9324bc9b23e26c154f5ea97e797abd 221 Pfam PF09365 Conserved hypothetical protein (DUF2461) 10 208 5.6E-48 T 28-03-2018 IPR012808 Conserved hypothetical protein CHP02453 CU254_RS10150 1d9324bc9b23e26c154f5ea97e797abd 221 TIGRFAM TIGR02453 TIGR02453: TIGR02453 family protein 7 212 2.8E-38 T 28-03-2018 IPR012808 Conserved hypothetical protein CHP02453 CU254_RS10150 1d9324bc9b23e26c154f5ea97e797abd 221 PIRSF PIRSF028451 2 216 9.5E-36 T 28-03-2018 IPR015996 Uncharacterised conserved protein UCP028451 CU254_RS23750 901e1fe63cc42962efbb429eb2fe5ddc 246 SUPERFAMILY SSF51735 4 245 1.12E-83 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS23750 901e1fe63cc42962efbb429eb2fe5ddc 246 Gene3D G3DSA:3.40.50.720 46 246 1.5E-67 T 28-03-2018 CU254_RS23750 901e1fe63cc42962efbb429eb2fe5ddc 246 Gene3D G3DSA:3.40.50.720 1 45 5.4E-12 T 28-03-2018 CU254_RS23750 901e1fe63cc42962efbb429eb2fe5ddc 246 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 187 0.0035 T 28-03-2018 CU254_RS23750 901e1fe63cc42962efbb429eb2fe5ddc 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 2.3E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23750 901e1fe63cc42962efbb429eb2fe5ddc 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 2.3E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23750 901e1fe63cc42962efbb429eb2fe5ddc 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 2.3E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23750 901e1fe63cc42962efbb429eb2fe5ddc 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 2.0E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23750 901e1fe63cc42962efbb429eb2fe5ddc 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 2.0E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23750 901e1fe63cc42962efbb429eb2fe5ddc 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 2.0E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23750 901e1fe63cc42962efbb429eb2fe5ddc 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 2.0E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23750 901e1fe63cc42962efbb429eb2fe5ddc 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 2.0E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23750 901e1fe63cc42962efbb429eb2fe5ddc 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 2.0E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23750 901e1fe63cc42962efbb429eb2fe5ddc 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 244 5.6E-72 T 28-03-2018 CU254_RS37775 f995a81208215804517d23e5c2b27a02 246 Gene3D G3DSA:1.10.3720.10 2 233 2.1E-46 T 28-03-2018 CU254_RS37775 f995a81208215804517d23e5c2b27a02 246 SUPERFAMILY SSF161098 21 216 3.66E-39 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS37775 f995a81208215804517d23e5c2b27a02 246 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 40 227 2.8E-25 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS37775 f995a81208215804517d23e5c2b27a02 246 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 21 119 2.5E-19 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CU254_RS40460 0d43e14392579d818985e682237b398c 325 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 87 3.5E-9 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CU254_RS40460 0d43e14392579d818985e682237b398c 325 Gene3D G3DSA:3.40.50.720 135 307 6.6E-41 T 28-03-2018 CU254_RS40460 0d43e14392579d818985e682237b398c 325 SUPERFAMILY SSF50129 1 138 1.67E-38 T 28-03-2018 IPR011032 GroES-like CU254_RS40460 0d43e14392579d818985e682237b398c 325 Gene3D G3DSA:3.90.180.10 1 134 4.1E-40 T 28-03-2018 CU254_RS40460 0d43e14392579d818985e682237b398c 325 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 1 322 2.0E-138 T 28-03-2018 IPR014189 Quinone oxidoreductase PIG3 Reactome: R-HSA-6803205 CU254_RS40460 0d43e14392579d818985e682237b398c 325 Pfam PF00107 Zinc-binding dehydrogenase 151 264 9.0E-27 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CU254_RS40460 0d43e14392579d818985e682237b398c 325 SMART SM00829 10 321 3.8E-36 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CU254_RS40460 0d43e14392579d818985e682237b398c 325 SUPERFAMILY SSF51735 114 285 3.2E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS40460 0d43e14392579d818985e682237b398c 325 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 140 161 - T 28-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 CU254_RS15440 50705111d026fabaa771b60ef5c4477e 370 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 28 126 1.5E-7 T 28-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CU254_RS15440 50705111d026fabaa771b60ef5c4477e 370 SUPERFAMILY SSF54826 8 127 2.0E-25 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CU254_RS15440 50705111d026fabaa771b60ef5c4477e 370 SUPERFAMILY SSF51604 114 368 5.11E-59 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CU254_RS15440 50705111d026fabaa771b60ef5c4477e 370 Gene3D G3DSA:3.20.20.120 133 357 1.4E-52 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CU254_RS15440 50705111d026fabaa771b60ef5c4477e 370 Gene3D G3DSA:3.30.390.10 5 132 2.8E-28 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CU254_RS15440 50705111d026fabaa771b60ef5c4477e 370 Pfam PF13378 Enolase C-terminal domain-like 148 358 1.5E-54 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CU254_RS15440 50705111d026fabaa771b60ef5c4477e 370 SMART SM00922 145 242 1.8E-20 T 28-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CU254_RS24735 8240d0d2e10337ebc11a05f2eb873a88 154 Pfam PF02464 Competence-damaged protein 5 152 1.9E-46 T 28-03-2018 IPR008136 CinA, C-terminal CU254_RS24735 8240d0d2e10337ebc11a05f2eb873a88 154 Gene3D G3DSA:3.90.950.20 1 154 5.1E-55 T 28-03-2018 CU254_RS24735 8240d0d2e10337ebc11a05f2eb873a88 154 SUPERFAMILY SSF142433 4 152 2.48E-43 T 28-03-2018 IPR008136 CinA, C-terminal CU254_RS24735 8240d0d2e10337ebc11a05f2eb873a88 154 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 9 151 7.8E-34 T 28-03-2018 IPR008136 CinA, C-terminal CU254_RS28070 61c2a20e604af07793c0fe35a3ddef07 564 SUPERFAMILY SSF54373 363 478 2.42E-26 T 28-03-2018 CU254_RS28070 61c2a20e604af07793c0fe35a3ddef07 564 Gene3D G3DSA:3.50.50.60 439 564 2.0E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS28070 61c2a20e604af07793c0fe35a3ddef07 564 Gene3D G3DSA:3.50.50.60 16 438 8.7E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS28070 61c2a20e604af07793c0fe35a3ddef07 564 Pfam PF01593 Flavin containing amine oxidoreductase 59 532 7.2E-47 T 28-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 CU254_RS28070 61c2a20e604af07793c0fe35a3ddef07 564 PRINTS PR00757 Flavin-containing amine oxidase signature 51 70 1.6E-6 T 28-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 CU254_RS28070 61c2a20e604af07793c0fe35a3ddef07 564 PRINTS PR00757 Flavin-containing amine oxidase signature 251 273 1.6E-6 T 28-03-2018 IPR001613 Flavin amine oxidase GO:0016491|GO:0055114 CU254_RS28070 61c2a20e604af07793c0fe35a3ddef07 564 SUPERFAMILY SSF51905 49 384 1.66E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS28070 61c2a20e604af07793c0fe35a3ddef07 564 SUPERFAMILY SSF51905 500 540 1.66E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS37475 ce244ee12b146c7e01c486da05f52dc7 278 Gene3D G3DSA:3.40.250.10 153 278 1.1E-28 T 28-03-2018 IPR001763 Rhodanese-like domain CU254_RS37475 ce244ee12b146c7e01c486da05f52dc7 278 SMART SM00450 8 122 3.1E-19 T 28-03-2018 IPR001763 Rhodanese-like domain CU254_RS37475 ce244ee12b146c7e01c486da05f52dc7 278 SMART SM00450 144 271 2.3E-20 T 28-03-2018 IPR001763 Rhodanese-like domain CU254_RS37475 ce244ee12b146c7e01c486da05f52dc7 278 SUPERFAMILY SSF52821 4 138 7.07E-35 T 28-03-2018 IPR001763 Rhodanese-like domain CU254_RS37475 ce244ee12b146c7e01c486da05f52dc7 278 Gene3D G3DSA:3.40.250.10 1 141 2.6E-28 T 28-03-2018 IPR001763 Rhodanese-like domain CU254_RS37475 ce244ee12b146c7e01c486da05f52dc7 278 ProSitePatterns PS00683 Rhodanese C-terminal signature. 255 265 - T 28-03-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 CU254_RS37475 ce244ee12b146c7e01c486da05f52dc7 278 SUPERFAMILY SSF52821 149 276 2.1E-34 T 28-03-2018 IPR001763 Rhodanese-like domain CU254_RS37475 ce244ee12b146c7e01c486da05f52dc7 278 Pfam PF00581 Rhodanese-like domain 9 118 1.5E-15 T 28-03-2018 IPR001763 Rhodanese-like domain CU254_RS37475 ce244ee12b146c7e01c486da05f52dc7 278 Pfam PF00581 Rhodanese-like domain 149 266 1.4E-16 T 28-03-2018 IPR001763 Rhodanese-like domain CU254_RS03005 b06134bbdf92cb5bfb1610e4c47c5896 196 Gene3D G3DSA:1.10.10.60 1 57 7.6E-12 T 28-03-2018 CU254_RS03005 b06134bbdf92cb5bfb1610e4c47c5896 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 4.9E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS03005 b06134bbdf92cb5bfb1610e4c47c5896 196 SUPERFAMILY SSF46689 3 75 4.77E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS03005 b06134bbdf92cb5bfb1610e4c47c5896 196 SUPERFAMILY SSF48498 85 188 8.53E-25 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS03005 b06134bbdf92cb5bfb1610e4c47c5896 196 Gene3D G3DSA:1.10.357.10 58 194 8.6E-29 T 28-03-2018 CU254_RS03005 b06134bbdf92cb5bfb1610e4c47c5896 196 Pfam PF13305 WHG domain 88 173 9.1E-14 T 28-03-2018 IPR025996 WHG domain CU254_RS13100 31dfebd122a6ced109b770972379f45b 396 Pfam PF00067 Cytochrome P450 199 365 1.1E-20 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS13100 31dfebd122a6ced109b770972379f45b 396 Pfam PF00067 Cytochrome P450 44 139 2.2E-6 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS13100 31dfebd122a6ced109b770972379f45b 396 SUPERFAMILY SSF48264 16 394 1.11E-85 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS13100 31dfebd122a6ced109b770972379f45b 396 PRINTS PR00385 P450 superfamily signature 232 249 8.4E-6 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS13100 31dfebd122a6ced109b770972379f45b 396 PRINTS PR00385 P450 superfamily signature 267 278 8.4E-6 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS13100 31dfebd122a6ced109b770972379f45b 396 PRINTS PR00385 P450 superfamily signature 335 344 8.4E-6 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS13100 31dfebd122a6ced109b770972379f45b 396 PRINTS PR00385 P450 superfamily signature 344 355 8.4E-6 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS13100 31dfebd122a6ced109b770972379f45b 396 Gene3D G3DSA:1.10.630.10 7 396 5.6E-72 T 28-03-2018 CU254_RS13100 31dfebd122a6ced109b770972379f45b 396 PRINTS PR00359 B-class P450 signature 188 210 3.4E-46 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS13100 31dfebd122a6ced109b770972379f45b 396 PRINTS PR00359 B-class P450 signature 344 355 3.4E-46 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS13100 31dfebd122a6ced109b770972379f45b 396 PRINTS PR00359 B-class P450 signature 267 278 3.4E-46 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS13100 31dfebd122a6ced109b770972379f45b 396 PRINTS PR00359 B-class P450 signature 285 312 3.4E-46 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS13100 31dfebd122a6ced109b770972379f45b 396 PRINTS PR00359 B-class P450 signature 134 150 3.4E-46 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS13100 31dfebd122a6ced109b770972379f45b 396 PRINTS PR00359 B-class P450 signature 335 344 3.4E-46 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS13100 31dfebd122a6ced109b770972379f45b 396 PRINTS PR00359 B-class P450 signature 151 166 3.4E-46 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS13100 31dfebd122a6ced109b770972379f45b 396 PRINTS PR00359 B-class P450 signature 87 98 3.4E-46 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS13100 31dfebd122a6ced109b770972379f45b 396 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 337 346 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CU254_RS32185 a17659afaac7fe8184e110c5472fcd6e 150 Gene3D G3DSA:2.30.110.10 2 147 2.7E-14 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS32185 a17659afaac7fe8184e110c5472fcd6e 150 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 7 80 4.4E-6 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CU254_RS32185 a17659afaac7fe8184e110c5472fcd6e 150 SUPERFAMILY SSF50475 6 137 5.8E-16 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS41545 419eb369d7bb525f0efb172f755f729b 243 Gene3D G3DSA:3.40.1350.10 17 154 2.8E-25 T 28-03-2018 CU254_RS25310 0a299a9e3f06598c4257e4f2032f03a6 221 SMART SM00895 82 209 4.0E-8 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS25310 0a299a9e3f06598c4257e4f2032f03a6 221 Gene3D G3DSA:1.20.120.530 75 220 5.6E-20 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS25310 0a299a9e3f06598c4257e4f2032f03a6 221 SMART SM00345 13 69 5.5E-4 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS25310 0a299a9e3f06598c4257e4f2032f03a6 221 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 65 3.9E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS25310 0a299a9e3f06598c4257e4f2032f03a6 221 Pfam PF07729 FCD domain 82 205 1.7E-12 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS25310 0a299a9e3f06598c4257e4f2032f03a6 221 SUPERFAMILY SSF48008 77 214 2.48E-20 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS25310 0a299a9e3f06598c4257e4f2032f03a6 221 Gene3D G3DSA:1.10.10.10 2 74 7.2E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS25310 0a299a9e3f06598c4257e4f2032f03a6 221 SUPERFAMILY SSF46785 3 70 2.86E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS05850 0ab696a25d68d3ec1473eb5802c59c44 234 Gene3D G3DSA:3.40.1130.10 28 226 1.5E-33 T 28-03-2018 CU254_RS05850 0ab696a25d68d3ec1473eb5802c59c44 234 SUPERFAMILY SSF69593 17 221 8.63E-35 T 28-03-2018 CU254_RS05850 0ab696a25d68d3ec1473eb5802c59c44 234 SMART SM00563 49 168 1.6E-25 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CU254_RS05850 0ab696a25d68d3ec1473eb5802c59c44 234 Pfam PF01553 Acyltransferase 35 165 1.7E-19 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CU254_RS01925 ae29109f2b576bfb7d58bbbf9de7a324 124 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS01925 ae29109f2b576bfb7d58bbbf9de7a324 124 PRINTS PR01034 Ribosomal protein S12 signature 77 94 1.3E-58 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS01925 ae29109f2b576bfb7d58bbbf9de7a324 124 PRINTS PR01034 Ribosomal protein S12 signature 58 77 1.3E-58 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS01925 ae29109f2b576bfb7d58bbbf9de7a324 124 PRINTS PR01034 Ribosomal protein S12 signature 42 57 1.3E-58 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS01925 ae29109f2b576bfb7d58bbbf9de7a324 124 PRINTS PR01034 Ribosomal protein S12 signature 94 110 1.3E-58 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS01925 ae29109f2b576bfb7d58bbbf9de7a324 124 PRINTS PR01034 Ribosomal protein S12 signature 27 42 1.3E-58 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS01925 ae29109f2b576bfb7d58bbbf9de7a324 124 PRINTS PR01034 Ribosomal protein S12 signature 110 122 1.3E-58 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS01925 ae29109f2b576bfb7d58bbbf9de7a324 124 SUPERFAMILY SSF50249 2 123 3.86E-52 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CU254_RS01925 ae29109f2b576bfb7d58bbbf9de7a324 124 Gene3D G3DSA:2.40.50.140 1 124 6.9E-64 T 28-03-2018 CU254_RS01925 ae29109f2b576bfb7d58bbbf9de7a324 124 Pfam PF00164 Ribosomal protein S12/S23 12 123 3.0E-43 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS01925 ae29109f2b576bfb7d58bbbf9de7a324 124 PIRSF PIRSF002133 1 124 2.3E-54 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS01925 ae29109f2b576bfb7d58bbbf9de7a324 124 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 39.496 T 28-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS01925 ae29109f2b576bfb7d58bbbf9de7a324 124 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 2 123 3.2E-67 T 28-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS34985 f9c4a163777030de90a9e2191938e259 568 Pfam PF00106 short chain dehydrogenase 303 491 6.3E-51 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS34985 f9c4a163777030de90a9e2191938e259 568 Pfam PF00561 alpha/beta hydrolase fold 20 130 1.1E-16 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS34985 f9c4a163777030de90a9e2191938e259 568 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 377 388 2.8E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS34985 f9c4a163777030de90a9e2191938e259 568 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 431 439 2.8E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS34985 f9c4a163777030de90a9e2191938e259 568 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 451 470 2.8E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS34985 f9c4a163777030de90a9e2191938e259 568 Gene3D G3DSA:3.40.50.1820 1 287 6.3E-40 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS34985 f9c4a163777030de90a9e2191938e259 568 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 472 489 1.1E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS34985 f9c4a163777030de90a9e2191938e259 568 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 377 388 1.1E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS34985 f9c4a163777030de90a9e2191938e259 568 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 425 441 1.1E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS34985 f9c4a163777030de90a9e2191938e259 568 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 303 320 1.1E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS34985 f9c4a163777030de90a9e2191938e259 568 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 451 470 1.1E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS34985 f9c4a163777030de90a9e2191938e259 568 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 438 466 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS34985 f9c4a163777030de90a9e2191938e259 568 SUPERFAMILY SSF53474 3 277 1.09E-43 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS34985 f9c4a163777030de90a9e2191938e259 568 SUPERFAMILY SSF51735 299 557 3.27E-67 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS34985 f9c4a163777030de90a9e2191938e259 568 Gene3D G3DSA:3.40.50.720 295 341 1.9E-9 T 28-03-2018 CU254_RS34985 f9c4a163777030de90a9e2191938e259 568 Gene3D G3DSA:3.40.50.720 342 538 5.5E-49 T 28-03-2018 CU254_RS36085 2bd6a0b3a8be7422c2936e449de3123e 391 Pfam PF04286 Protein of unknown function (DUF445) 4 116 1.7E-10 T 28-03-2018 IPR007383 Protein of unknown function DUF445 CU254_RS24190 cac948244a4fadcd03a4a7bea6a069a6 611 Gene3D G3DSA:3.40.50.10540 4 372 5.4E-50 T 28-03-2018 IPR023606 CoA-transferase family III domain CU254_RS24190 cac948244a4fadcd03a4a7bea6a069a6 611 Gene3D G3DSA:3.40.50.10540 380 610 7.7E-59 T 28-03-2018 IPR023606 CoA-transferase family III domain CU254_RS24190 cac948244a4fadcd03a4a7bea6a069a6 611 SUPERFAMILY SSF89796 6 359 2.09E-52 T 28-03-2018 IPR023606 CoA-transferase family III domain CU254_RS24190 cac948244a4fadcd03a4a7bea6a069a6 611 Pfam PF02515 CoA-transferase family III 386 585 2.7E-52 T 28-03-2018 IPR003673 CoA-transferase family III GO:0003824 CU254_RS24190 cac948244a4fadcd03a4a7bea6a069a6 611 Pfam PF02515 CoA-transferase family III 9 348 1.1E-45 T 28-03-2018 IPR003673 CoA-transferase family III GO:0003824 CU254_RS24190 cac948244a4fadcd03a4a7bea6a069a6 611 SUPERFAMILY SSF89796 384 590 7.59E-54 T 28-03-2018 IPR023606 CoA-transferase family III domain CU254_RS12980 5e1f1fa6a815298dfc754bddf8a65190 513 Gene3D G3DSA:2.30.38.10 333 411 6.0E-14 T 28-03-2018 CU254_RS12980 5e1f1fa6a815298dfc754bddf8a65190 513 Pfam PF00501 AMP-binding enzyme 34 417 6.1E-72 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS12980 5e1f1fa6a815298dfc754bddf8a65190 513 Gene3D G3DSA:3.40.50.980 24 179 5.4E-32 T 28-03-2018 CU254_RS12980 5e1f1fa6a815298dfc754bddf8a65190 513 SUPERFAMILY SSF56801 8 509 2.62E-124 T 28-03-2018 CU254_RS12980 5e1f1fa6a815298dfc754bddf8a65190 513 Gene3D G3DSA:3.40.50.980 180 332 4.0E-35 T 28-03-2018 CU254_RS12980 5e1f1fa6a815298dfc754bddf8a65190 513 ProSitePatterns PS00455 Putative AMP-binding domain signature. 179 190 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS12980 5e1f1fa6a815298dfc754bddf8a65190 513 Pfam PF13193 AMP-binding enzyme C-terminal domain 426 501 6.2E-16 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS12980 5e1f1fa6a815298dfc754bddf8a65190 513 Gene3D G3DSA:3.30.300.30 412 510 1.2E-23 T 28-03-2018 CU254_RS42060 b58c59a06cae1cdb2a9a64093b97c96c 405 SUPERFAMILY SSF52777 168 387 1.01E-19 T 28-03-2018 CU254_RS42060 b58c59a06cae1cdb2a9a64093b97c96c 405 SUPERFAMILY SSF52777 22 145 2.56E-16 T 28-03-2018 CU254_RS42060 b58c59a06cae1cdb2a9a64093b97c96c 405 Pfam PF16911 Phthiocerol/phthiodiolone dimycocerosyl transferase C-terminus 271 378 1.3E-10 T 28-03-2018 IPR031641 Phthiocerol/phthiodiolone dimycocerosyl transferase, C-terminal CU254_RS42060 b58c59a06cae1cdb2a9a64093b97c96c 405 Gene3D G3DSA:3.30.559.10 1 203 1.2E-10 T 28-03-2018 CU254_RS37750 3aeb67eaea70d39753d5e553385ff99c 293 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 7 286 26.317 T 28-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CU254_RS37750 3aeb67eaea70d39753d5e553385ff99c 293 Pfam PF01259 SAICAR synthetase 10 258 5.4E-105 T 28-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CU254_RS37750 3aeb67eaea70d39753d5e553385ff99c 293 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 9 286 2.6E-74 T 28-03-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 CU254_RS37750 3aeb67eaea70d39753d5e553385ff99c 293 Gene3D G3DSA:3.30.200.20 5 102 5.7E-37 T 28-03-2018 CU254_RS37750 3aeb67eaea70d39753d5e553385ff99c 293 SUPERFAMILY SSF56104 4 288 1.28E-101 T 28-03-2018 CU254_RS37750 3aeb67eaea70d39753d5e553385ff99c 293 Gene3D G3DSA:3.30.470.20 103 238 1.9E-56 T 28-03-2018 CU254_RS37750 3aeb67eaea70d39753d5e553385ff99c 293 ProSitePatterns PS01057 SAICAR synthetase signature 1. 95 109 - T 28-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CU254_RS37750 3aeb67eaea70d39753d5e553385ff99c 293 ProSitePatterns PS01058 SAICAR synthetase signature 2. 194 202 - T 28-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CU254_RS09225 cba3b6cee2a35dbf21d3326b956d3f14 153 Pfam PF09278 MerR, DNA binding 50 115 2.7E-20 T 28-03-2018 IPR015358 Transcription regulator MerR, DNA binding CU254_RS09225 cba3b6cee2a35dbf21d3326b956d3f14 153 Pfam PF00376 MerR family regulatory protein 9 45 1.1E-14 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS09225 cba3b6cee2a35dbf21d3326b956d3f14 153 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 20 33 1.5E-12 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS09225 cba3b6cee2a35dbf21d3326b956d3f14 153 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 43 63 1.5E-12 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS09225 cba3b6cee2a35dbf21d3326b956d3f14 153 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 9 20 1.5E-12 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS09225 cba3b6cee2a35dbf21d3326b956d3f14 153 Gene3D G3DSA:1.10.1660.10 63 136 3.0E-14 T 28-03-2018 CU254_RS09225 cba3b6cee2a35dbf21d3326b956d3f14 153 TIGRFAM TIGR01950 SoxR: redox-sensitive transcriptional activator SoxR 8 145 3.5E-62 T 28-03-2018 IPR010211 Redox-sensitive transcriptional activator SoxR GO:0003677|GO:0006355|GO:0006979|GO:0051537 CU254_RS09225 cba3b6cee2a35dbf21d3326b956d3f14 153 SMART SM00422 8 76 2.0E-25 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS09225 cba3b6cee2a35dbf21d3326b956d3f14 153 SUPERFAMILY SSF46955 8 130 5.13E-30 T 28-03-2018 IPR009061 Putative DNA-binding domain CU254_RS09225 cba3b6cee2a35dbf21d3326b956d3f14 153 Gene3D G3DSA:1.10.1660.10 4 62 5.9E-21 T 28-03-2018 CU254_RS25895 b21f577cd02c9c13b145df2dc5ff9969 384 Gene3D G3DSA:1.20.1250.20 195 381 4.5E-9 T 28-03-2018 CU254_RS25895 b21f577cd02c9c13b145df2dc5ff9969 384 Pfam PF07690 Major Facilitator Superfamily 25 282 3.7E-12 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS25895 b21f577cd02c9c13b145df2dc5ff9969 384 SUPERFAMILY SSF103473 10 378 8.11E-25 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS25895 b21f577cd02c9c13b145df2dc5ff9969 384 Gene3D G3DSA:1.20.1250.20 2 182 2.5E-10 T 28-03-2018 CU254_RS16485 29ef9fb514dcbbb92c03bbff1d142976 627 Gene3D G3DSA:1.20.58.460 470 623 3.2E-35 T 28-03-2018 CU254_RS16485 29ef9fb514dcbbb92c03bbff1d142976 627 Gene3D G3DSA:3.30.379.10 19 154 7.5E-21 T 28-03-2018 CU254_RS16485 29ef9fb514dcbbb92c03bbff1d142976 627 SUPERFAMILY SSF140657 492 620 3.92E-5 T 28-03-2018 CU254_RS16485 29ef9fb514dcbbb92c03bbff1d142976 627 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 32 154 2.5E-23 T 28-03-2018 IPR015882 Beta-hexosaminidase, bacteial type, N-terminal KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822 CU254_RS16485 29ef9fb514dcbbb92c03bbff1d142976 627 SUPERFAMILY SSF55545 32 156 8.64E-21 T 28-03-2018 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CU254_RS16485 29ef9fb514dcbbb92c03bbff1d142976 627 Gene3D G3DSA:3.20.20.80 157 469 4.8E-110 T 28-03-2018 CU254_RS16485 29ef9fb514dcbbb92c03bbff1d142976 627 Pfam PF07555 beta-N-acetylglucosaminidase 160 471 3.0E-107 T 28-03-2018 IPR011496 Beta-N-acetylglucosaminidase MetaCyc: PWY-7437 CU254_RS16485 29ef9fb514dcbbb92c03bbff1d142976 627 SUPERFAMILY SSF51445 158 481 3.68E-101 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS08445 543aa43f42ea3b7a238a2894a913fdcc 321 SUPERFAMILY SSF55729 1 316 1.15E-35 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS08445 543aa43f42ea3b7a238a2894a913fdcc 321 Gene3D G3DSA:3.40.630.30 160 317 1.5E-21 T 28-03-2018 CU254_RS08445 543aa43f42ea3b7a238a2894a913fdcc 321 Gene3D G3DSA:3.40.630.30 1 154 9.8E-15 T 28-03-2018 CU254_RS08445 543aa43f42ea3b7a238a2894a913fdcc 321 Pfam PF00583 Acetyltransferase (GNAT) family 197 307 1.0E-10 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS41450 1ffb91fc8c495274b0700e6ff49960d1 361 SUPERFAMILY SSF53474 48 359 6.71E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS41450 1ffb91fc8c495274b0700e6ff49960d1 361 Pfam PF12697 Alpha/beta hydrolase family 81 342 4.0E-16 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS41450 1ffb91fc8c495274b0700e6ff49960d1 361 Gene3D G3DSA:3.40.50.1820 5 361 2.7E-31 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS24445 81291fb165ca0cefd928bc0a5404c783 231 SUPERFAMILY SSF46785 2 89 4.27E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS24445 81291fb165ca0cefd928bc0a5404c783 231 Gene3D G3DSA:1.10.10.10 102 195 0.11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS24445 81291fb165ca0cefd928bc0a5404c783 231 SMART SM00418 8 87 1.2E-13 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS24445 81291fb165ca0cefd928bc0a5404c783 231 Pfam PF12840 Helix-turn-helix domain 7 67 4.1E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS24445 81291fb165ca0cefd928bc0a5404c783 231 Gene3D G3DSA:1.10.10.10 1 95 1.9E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS23130 79c194a2af6a119ab05922c72b2eecc1 378 Gene3D G3DSA:3.90.1200.10 97 341 4.0E-16 T 28-03-2018 CU254_RS23130 79c194a2af6a119ab05922c72b2eecc1 378 SUPERFAMILY SSF56112 45 265 9.33E-24 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS35625 ba0d490d5b4d3d5b4de9d509decf0822 159 Gene3D G3DSA:3.40.630.30 1 159 1.7E-30 T 28-03-2018 CU254_RS35625 ba0d490d5b4d3d5b4de9d509decf0822 159 SUPERFAMILY SSF55729 2 121 4.56E-21 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS35625 ba0d490d5b4d3d5b4de9d509decf0822 159 Pfam PF00583 Acetyltransferase (GNAT) family 31 121 1.8E-15 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS35625 ba0d490d5b4d3d5b4de9d509decf0822 159 TIGRFAM TIGR02406 ectoine_EctA: diaminobutyrate acetyltransferase 2 157 1.2E-58 T 28-03-2018 IPR012772 L-2,4-diaminobutyric acid acetyltransferase GO:0019491|GO:0033816 KEGG: 00250+2.3.1.17|KEGG: 00260+2.3.1.178 CU254_RS40375 f0e1af31bd1781fc6383d5a65d0b179c 457 SUPERFAMILY SSF56176 12 186 1.07E-37 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CU254_RS40375 f0e1af31bd1781fc6383d5a65d0b179c 457 Gene3D G3DSA:3.30.43.10 4 69 3.9E-4 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CU254_RS40375 f0e1af31bd1781fc6383d5a65d0b179c 457 Pfam PF01565 FAD binding domain 27 156 3.4E-26 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CU254_RS40375 f0e1af31bd1781fc6383d5a65d0b179c 457 Gene3D G3DSA:3.30.465.10 70 190 4.3E-30 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CU254_RS40375 f0e1af31bd1781fc6383d5a65d0b179c 457 Pfam PF04030 D-arabinono-1,4-lactone oxidase 394 454 5.0E-9 T 28-03-2018 IPR007173 D-arabinono-1,4-lactone oxidase GO:0003885|GO:0016020|GO:0055114 CU254_RS24205 637c298442ff24500414dae1a567285f 565 Gene3D G3DSA:3.40.50.1820 314 557 1.1E-11 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS24205 637c298442ff24500414dae1a567285f 565 Gene3D G3DSA:1.10.287.850 7 105 7.2E-4 T 28-03-2018 CU254_RS24205 637c298442ff24500414dae1a567285f 565 Pfam PF06259 Alpha/beta hydrolase 318 493 3.0E-33 T 28-03-2018 IPR010427 Protein of unknown function DUF1023 CU254_RS24205 637c298442ff24500414dae1a567285f 565 SUPERFAMILY SSF53474 326 490 3.82E-6 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS02895 f679c60194707e01dc2bf3329af34b0b 309 Gene3D G3DSA:3.40.50.1360 50 301 8.8E-30 T 28-03-2018 CU254_RS02895 f679c60194707e01dc2bf3329af34b0b 309 Pfam PF04198 Putative sugar-binding domain 51 299 2.4E-48 T 28-03-2018 IPR007324 Sugar-binding domain, putative GO:0030246 CU254_RS02895 f679c60194707e01dc2bf3329af34b0b 309 Gene3D G3DSA:1.10.10.60 1 42 1.5E-7 T 28-03-2018 CU254_RS02895 f679c60194707e01dc2bf3329af34b0b 309 SUPERFAMILY SSF100950 51 301 2.18E-49 T 28-03-2018 CU254_RS24095 322067a4b8ed02e7cfa66039deb40e87 279 Gene3D G3DSA:3.20.20.80 63 278 2.1E-58 T 28-03-2018 CU254_RS24095 322067a4b8ed02e7cfa66039deb40e87 279 Pfam PF01183 Glycosyl hydrolases family 25 81 260 8.2E-48 T 28-03-2018 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 CU254_RS24095 322067a4b8ed02e7cfa66039deb40e87 279 ProSitePatterns PS00953 Glycosyl hydrolases family 25 active sites signature. 82 115 - T 28-03-2018 IPR008270 Glycoside hydrolase, family 25, active site GO:0003796|GO:0009253|GO:0016998 CU254_RS24095 322067a4b8ed02e7cfa66039deb40e87 279 SUPERFAMILY SSF51445 78 277 5.83E-58 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS24095 322067a4b8ed02e7cfa66039deb40e87 279 SMART SM00641 78 186 1.7E-38 T 28-03-2018 IPR018077 Glycoside hydrolase, family 25 subgroup CU254_RS19140 df863413da7e3d7e0ca9cdcd25db2b70 311 SUPERFAMILY SSF46689 258 306 1.16E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS19140 df863413da7e3d7e0ca9cdcd25db2b70 311 Pfam PF12852 Cupin 2 192 1.4E-50 T 28-03-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain CU254_RS19140 df863413da7e3d7e0ca9cdcd25db2b70 311 Gene3D G3DSA:1.10.10.60 65 260 8.5E-11 T 28-03-2018 CU254_RS19140 df863413da7e3d7e0ca9cdcd25db2b70 311 SUPERFAMILY SSF46689 207 255 1.08E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS19140 df863413da7e3d7e0ca9cdcd25db2b70 311 SMART SM00342 222 306 3.6E-29 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS19140 df863413da7e3d7e0ca9cdcd25db2b70 311 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 259 302 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CU254_RS19140 df863413da7e3d7e0ca9cdcd25db2b70 311 Gene3D G3DSA:1.10.10.60 261 310 8.1E-14 T 28-03-2018 CU254_RS19140 df863413da7e3d7e0ca9cdcd25db2b70 311 Pfam PF12833 Helix-turn-helix domain 228 307 5.4E-20 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS19140 df863413da7e3d7e0ca9cdcd25db2b70 311 Gene3D G3DSA:3.30.70.1450 23 64 0.0038 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CU254_RS15310 f61f70076ee599a08f6aaa331c90a969 379 Gene3D G3DSA:1.20.140.10 221 379 2.8E-29 T 28-03-2018 CU254_RS15310 f61f70076ee599a08f6aaa331c90a969 379 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 11 122 2.6E-19 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS15310 f61f70076ee599a08f6aaa331c90a969 379 SUPERFAMILY SSF56645 2 244 6.41E-70 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS15310 f61f70076ee599a08f6aaa331c90a969 379 Gene3D G3DSA:2.40.110.10 125 220 2.2E-32 T 28-03-2018 CU254_RS15310 f61f70076ee599a08f6aaa331c90a969 379 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 126 215 5.4E-20 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CU254_RS15310 f61f70076ee599a08f6aaa331c90a969 379 SUPERFAMILY SSF47203 232 377 3.22E-16 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS15310 f61f70076ee599a08f6aaa331c90a969 379 Gene3D G3DSA:1.10.540.10 1 124 2.9E-24 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS15310 f61f70076ee599a08f6aaa331c90a969 379 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 232 373 1.1E-15 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS40690 6594a8f87fb5128003a64f37f1a4d721 379 SUPERFAMILY SSF53187 4 188 2.68E-67 T 28-03-2018 CU254_RS40690 6594a8f87fb5128003a64f37f1a4d721 379 SUPERFAMILY SSF53187 291 371 2.68E-67 T 28-03-2018 CU254_RS40690 6594a8f87fb5128003a64f37f1a4d721 379 PIRSF PIRSF005962 2 375 2.0E-93 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CU254_RS40690 6594a8f87fb5128003a64f37f1a4d721 379 Pfam PF07687 Peptidase dimerisation domain 176 272 1.4E-13 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CU254_RS40690 6594a8f87fb5128003a64f37f1a4d721 379 Gene3D G3DSA:3.40.630.10 3 241 2.5E-40 T 28-03-2018 CU254_RS40690 6594a8f87fb5128003a64f37f1a4d721 379 SUPERFAMILY SSF55031 176 283 2.49E-28 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CU254_RS40690 6594a8f87fb5128003a64f37f1a4d721 379 Pfam PF01546 Peptidase family M20/M25/M40 63 371 9.4E-22 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CU254_RS40690 6594a8f87fb5128003a64f37f1a4d721 379 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 6 360 1.4E-80 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CU254_RS40690 6594a8f87fb5128003a64f37f1a4d721 379 Gene3D G3DSA:3.40.630.10 242 376 1.1E-16 T 28-03-2018 CU254_RS02940 a3e122096042db33192216365585248f 64 SUPERFAMILY SSF54862 2 62 9.02E-12 T 28-03-2018 CU254_RS02940 a3e122096042db33192216365585248f 64 Pfam PF06902 Divergent 4Fe-4S mono-cluster 2 62 2.5E-12 T 28-03-2018 IPR010693 Divergent 4Fe-4S mono-cluster CU254_RS02940 a3e122096042db33192216365585248f 64 Gene3D G3DSA:3.30.70.20 1 64 6.8E-7 T 28-03-2018 CU254_RS30825 7bbb81173f46abf1f041b42588818322 560 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 153 323 2.0E-41 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CU254_RS30825 7bbb81173f46abf1f041b42588818322 560 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 428 513 2.9E-17 T 28-03-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain CU254_RS30825 7bbb81173f46abf1f041b42588818322 560 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 153 323 2.5E-34 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CU254_RS11195 dfd816ac9c2ccc54935de8b0895875e2 357 Gene3D G3DSA:3.30.470.30 4 135 3.7E-30 T 28-03-2018 CU254_RS11195 dfd816ac9c2ccc54935de8b0895875e2 357 Gene3D G3DSA:2.40.50.140 195 344 3.8E-28 T 28-03-2018 CU254_RS11195 dfd816ac9c2ccc54935de8b0895875e2 357 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 29 37 - T 28-03-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 CU254_RS11195 dfd816ac9c2ccc54935de8b0895875e2 357 SUPERFAMILY SSF56091 7 188 5.14E-41 T 28-03-2018 CU254_RS11195 dfd816ac9c2ccc54935de8b0895875e2 357 Pfam PF01068 ATP dependent DNA ligase domain 11 194 9.1E-32 T 28-03-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 CU254_RS11195 dfd816ac9c2ccc54935de8b0895875e2 357 Pfam PF04679 ATP dependent DNA ligase C terminal region 216 327 9.3E-15 T 28-03-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 CU254_RS11195 dfd816ac9c2ccc54935de8b0895875e2 357 Gene3D G3DSA:3.30.1490.70 136 194 1.9E-9 T 28-03-2018 CU254_RS11195 dfd816ac9c2ccc54935de8b0895875e2 357 SUPERFAMILY SSF50249 197 333 7.54E-10 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CU254_RS40810 8605b8c65e47fc3b1140182f6c8646c8 252 Gene3D G3DSA:3.10.450.50 128 251 1.2E-20 T 28-03-2018 CU254_RS40810 8605b8c65e47fc3b1140182f6c8646c8 252 Gene3D G3DSA:3.10.450.50 2 127 4.0E-15 T 28-03-2018 CU254_RS40810 8605b8c65e47fc3b1140182f6c8646c8 252 Pfam PF12680 SnoaL-like domain 14 114 1.5E-10 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CU254_RS40810 8605b8c65e47fc3b1140182f6c8646c8 252 Pfam PF12680 SnoaL-like domain 135 240 1.6E-12 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CU254_RS40810 8605b8c65e47fc3b1140182f6c8646c8 252 SUPERFAMILY SSF54427 130 245 4.3E-27 T 28-03-2018 IPR032710 NTF2-like domain CU254_RS40810 8605b8c65e47fc3b1140182f6c8646c8 252 SUPERFAMILY SSF54427 5 126 2.8E-18 T 28-03-2018 IPR032710 NTF2-like domain CU254_RS31965 c4b53c6996060054107118ba23659c0c 329 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 222 238 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CU254_RS31965 c4b53c6996060054107118ba23659c0c 329 Gene3D G3DSA:3.40.50.720 130 284 5.8E-46 T 28-03-2018 CU254_RS31965 c4b53c6996060054107118ba23659c0c 329 SUPERFAMILY SSF52283 33 131 1.04E-9 T 28-03-2018 CU254_RS31965 c4b53c6996060054107118ba23659c0c 329 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 283 5.7E-50 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CU254_RS31965 c4b53c6996060054107118ba23659c0c 329 SUPERFAMILY SSF51735 103 282 1.68E-48 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS31965 c4b53c6996060054107118ba23659c0c 329 Gene3D G3DSA:3.40.50.720 10 129 7.7E-24 T 28-03-2018 CU254_RS23755 387642fb35fcb0e698e25dbe59b9ed76 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 1.9E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23755 387642fb35fcb0e698e25dbe59b9ed76 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 1.9E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23755 387642fb35fcb0e698e25dbe59b9ed76 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 1.9E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23755 387642fb35fcb0e698e25dbe59b9ed76 245 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 180 0.002 T 28-03-2018 CU254_RS23755 387642fb35fcb0e698e25dbe59b9ed76 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 7.1E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23755 387642fb35fcb0e698e25dbe59b9ed76 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 7.1E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23755 387642fb35fcb0e698e25dbe59b9ed76 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 7.1E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23755 387642fb35fcb0e698e25dbe59b9ed76 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 7.1E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23755 387642fb35fcb0e698e25dbe59b9ed76 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 7.1E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23755 387642fb35fcb0e698e25dbe59b9ed76 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 7.1E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23755 387642fb35fcb0e698e25dbe59b9ed76 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 243 3.8E-63 T 28-03-2018 CU254_RS23755 387642fb35fcb0e698e25dbe59b9ed76 245 SUPERFAMILY SSF51735 1 244 2.58E-73 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS23755 387642fb35fcb0e698e25dbe59b9ed76 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 136 164 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS23755 387642fb35fcb0e698e25dbe59b9ed76 245 Gene3D G3DSA:3.40.50.720 48 245 1.0E-57 T 28-03-2018 CU254_RS23755 387642fb35fcb0e698e25dbe59b9ed76 245 Gene3D G3DSA:3.40.50.720 1 47 1.3E-9 T 28-03-2018 CU254_RS04425 9f7983be6422637c399e748e60b9cf9c 1107 Pfam PF16995 Transmembrane region of lysyl-tRNA synthetase 21 243 1.2E-28 T 28-03-2018 IPR031553 Lysyl-tRNA synthetase, N-terminal transmembrane region KEGG: 00970+6.1.1.6 CU254_RS04425 9f7983be6422637c399e748e60b9cf9c 1107 Gene3D G3DSA:2.40.50.140 628 754 3.3E-34 T 28-03-2018 CU254_RS04425 9f7983be6422637c399e748e60b9cf9c 1107 Gene3D G3DSA:1.10.10.10 352 627 0.03 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS04425 9f7983be6422637c399e748e60b9cf9c 1107 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 620 1106 7.8E-149 T 28-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CU254_RS04425 9f7983be6422637c399e748e60b9cf9c 1107 PRINTS PR00982 Lysyl-tRNA synthetase signature 843 856 7.0E-31 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CU254_RS04425 9f7983be6422637c399e748e60b9cf9c 1107 PRINTS PR00982 Lysyl-tRNA synthetase signature 861 878 7.0E-31 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CU254_RS04425 9f7983be6422637c399e748e60b9cf9c 1107 PRINTS PR00982 Lysyl-tRNA synthetase signature 989 1005 7.0E-31 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CU254_RS04425 9f7983be6422637c399e748e60b9cf9c 1107 PRINTS PR00982 Lysyl-tRNA synthetase signature 798 808 7.0E-31 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CU254_RS04425 9f7983be6422637c399e748e60b9cf9c 1107 PRINTS PR00982 Lysyl-tRNA synthetase signature 814 830 7.0E-31 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CU254_RS04425 9f7983be6422637c399e748e60b9cf9c 1107 Pfam PF01336 OB-fold nucleic acid binding domain 670 744 2.5E-11 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CU254_RS04425 9f7983be6422637c399e748e60b9cf9c 1107 Pfam PF00152 tRNA synthetases class II (D, K and N) 762 1102 1.9E-71 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CU254_RS04425 9f7983be6422637c399e748e60b9cf9c 1107 Gene3D G3DSA:3.30.930.10 755 1103 2.1E-87 T 28-03-2018 CU254_RS04425 9f7983be6422637c399e748e60b9cf9c 1107 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 261 560 2.9E-100 T 28-03-2018 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal CU254_RS04425 9f7983be6422637c399e748e60b9cf9c 1107 SUPERFAMILY SSF55681 761 1104 2.79E-100 T 28-03-2018 CU254_RS04425 9f7983be6422637c399e748e60b9cf9c 1107 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 624 1106 35.944 T 28-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CU254_RS04425 9f7983be6422637c399e748e60b9cf9c 1107 SUPERFAMILY SSF50249 619 754 6.43E-33 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CU254_RS37085 dd7edcb171ab07a0d7e8d922686b6719 198 Pfam PF00633 Helix-hairpin-helix motif 2 27 5.4E-6 T 28-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 CU254_RS37085 dd7edcb171ab07a0d7e8d922686b6719 198 SUPERFAMILY SSF111304 3 198 1.7E-70 T 28-03-2018 IPR023627 Recombination protein RecR CU254_RS37085 dd7edcb171ab07a0d7e8d922686b6719 198 Pfam PF02132 RecR protein 39 77 1.5E-14 T 28-03-2018 IPR023628 Recombination protein RecR, C4-type zinc finger CU254_RS37085 dd7edcb171ab07a0d7e8d922686b6719 198 Pfam PF13662 Toprim domain 80 171 2.8E-25 T 28-03-2018 IPR006171 TOPRIM domain CU254_RS37085 dd7edcb171ab07a0d7e8d922686b6719 198 TIGRFAM TIGR00615 recR: recombination protein RecR 2 196 3.0E-82 T 28-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 CU254_RS37085 dd7edcb171ab07a0d7e8d922686b6719 198 Hamap MF_00017 Recombination protein RecR [recR]. 1 198 101.069 T 28-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 CU254_RS37085 dd7edcb171ab07a0d7e8d922686b6719 198 Gene3D G3DSA:3.40.1360.10 76 170 3.5E-39 T 28-03-2018 CU254_RS37085 dd7edcb171ab07a0d7e8d922686b6719 198 ProSitePatterns PS01300 RecR protein signature. 56 77 - T 28-03-2018 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 CU254_RS37085 dd7edcb171ab07a0d7e8d922686b6719 198 SMART SM00493 79 164 1.3E-16 T 28-03-2018 IPR006171 TOPRIM domain CU254_RS39140 5deafbe2720e02f7d4a17997d1300a30 721 Gene3D G3DSA:2.60.40.10 43 182 1.1E-7 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS32350 bdd6a2c7c39502e3926055e007463dd9 159 SUPERFAMILY SSF55826 6 156 4.32E-44 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CU254_RS32350 bdd6a2c7c39502e3926055e007463dd9 159 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 6 156 3.5E-51 T 28-03-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC CU254_RS32350 bdd6a2c7c39502e3926055e007463dd9 159 Pfam PF04073 Aminoacyl-tRNA editing domain 36 148 3.7E-27 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CU254_RS32350 bdd6a2c7c39502e3926055e007463dd9 159 PIRSF PIRSF006181 1 159 1.1E-50 T 28-03-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC CU254_RS32350 bdd6a2c7c39502e3926055e007463dd9 159 Gene3D G3DSA:3.90.960.10 2 159 1.1E-44 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CU254_RS23635 da8fcd5bd578e1493d6196dd53c74d76 78 Pfam PF13244 Domain of unknown function (DUF4040) 12 76 1.4E-16 T 28-03-2018 IPR025383 Domain of unknown function DUF4040 CU254_RS02965 831f0a41436673c22aedefe83a9fe4a4 282 Pfam PF13560 Helix-turn-helix domain 11 74 2.6E-10 T 28-03-2018 CU254_RS02965 831f0a41436673c22aedefe83a9fe4a4 282 SUPERFAMILY SSF47413 6 77 4.44E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS02965 831f0a41436673c22aedefe83a9fe4a4 282 Gene3D G3DSA:1.10.260.40 2 81 2.3E-13 T 28-03-2018 CU254_RS02965 831f0a41436673c22aedefe83a9fe4a4 282 SMART SM00530 15 71 3.2E-5 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS37500 a820fdb11584d5ef3dbe2b5c05ed8199 283 SUPERFAMILY SSF50891 174 281 1.33E-12 T 28-03-2018 IPR029000 Cyclophilin-like domain CU254_RS37500 a820fdb11584d5ef3dbe2b5c05ed8199 283 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 3 281 7.7E-83 T 28-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CU254_RS37500 a820fdb11584d5ef3dbe2b5c05ed8199 283 SMART SM00797 25 283 9.9E-88 T 28-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CU254_RS37500 a820fdb11584d5ef3dbe2b5c05ed8199 283 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 26 280 7.3E-82 T 28-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CU254_RS26220 f7a83370b64a0764aa8f460aec746447 103 Pfam PF12697 Alpha/beta hydrolase family 3 87 4.7E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS26220 f7a83370b64a0764aa8f460aec746447 103 Gene3D G3DSA:3.40.50.1820 1 102 3.4E-11 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS26220 f7a83370b64a0764aa8f460aec746447 103 SUPERFAMILY SSF53474 1 85 1.7E-13 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS24605 75bc0631667842ab78f17552ab3f4ed7 504 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 32 481 2.8E-121 T 28-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CU254_RS24605 75bc0631667842ab78f17552ab3f4ed7 504 Pfam PF08245 Mur ligase middle domain 132 319 1.6E-40 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CU254_RS24605 75bc0631667842ab78f17552ab3f4ed7 504 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 4 482 31.531 T 28-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CU254_RS24605 75bc0631667842ab78f17552ab3f4ed7 504 Pfam PF01225 Mur ligase family, catalytic domain 30 79 3.8E-9 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CU254_RS24605 75bc0631667842ab78f17552ab3f4ed7 504 Gene3D G3DSA:3.40.1390.10 2 113 4.5E-27 T 28-03-2018 CU254_RS24605 75bc0631667842ab78f17552ab3f4ed7 504 Gene3D G3DSA:3.40.1190.10 114 335 2.7E-54 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CU254_RS24605 75bc0631667842ab78f17552ab3f4ed7 504 SUPERFAMILY SSF53244 342 481 6.23E-34 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CU254_RS24605 75bc0631667842ab78f17552ab3f4ed7 504 SUPERFAMILY SSF53623 127 336 5.36E-51 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CU254_RS24605 75bc0631667842ab78f17552ab3f4ed7 504 Gene3D G3DSA:3.90.190.20 339 493 2.5E-50 T 28-03-2018 CU254_RS24605 75bc0631667842ab78f17552ab3f4ed7 504 SUPERFAMILY SSF63418 3 82 5.23E-18 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CU254_RS24605 75bc0631667842ab78f17552ab3f4ed7 504 Pfam PF02875 Mur ligase family, glutamate ligase domain 341 428 3.2E-21 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CU254_RS06265 c4583eb2b9657f10524e09e084104356 429 Gene3D G3DSA:3.40.50.980 83 258 6.5E-21 T 28-03-2018 CU254_RS06265 c4583eb2b9657f10524e09e084104356 429 TIGRFAM TIGR02155 PA_CoA_ligase: phenylacetate-CoA ligase 10 428 8.6E-211 T 28-03-2018 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 CU254_RS06265 c4583eb2b9657f10524e09e084104356 429 Pfam PF14535 AMP-binding enzyme C-terminal domain 335 428 6.1E-24 T 28-03-2018 IPR028154 AMP-dependent ligase, C-terminal CU254_RS06265 c4583eb2b9657f10524e09e084104356 429 Gene3D G3DSA:3.30.300.30 325 429 6.4E-9 T 28-03-2018 CU254_RS06265 c4583eb2b9657f10524e09e084104356 429 SUPERFAMILY SSF56801 23 393 1.09E-60 T 28-03-2018 CU254_RS06265 c4583eb2b9657f10524e09e084104356 429 Pfam PF00501 AMP-binding enzyme 84 288 2.4E-14 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS06265 c4583eb2b9657f10524e09e084104356 429 PIRSF PIRSF006444 2 429 1.2E-201 T 28-03-2018 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 CU254_RS01260 4da71da0330a202dc9256a02e6181017 358 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 34 318 2.3E-50 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CU254_RS01260 4da71da0330a202dc9256a02e6181017 358 SUPERFAMILY SSF53686 26 338 4.98E-71 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CU254_RS01260 4da71da0330a202dc9256a02e6181017 358 Gene3D G3DSA:3.40.50.1100 36 142 2.0E-23 T 28-03-2018 CU254_RS01260 4da71da0330a202dc9256a02e6181017 358 Gene3D G3DSA:3.40.50.1100 143 332 4.3E-40 T 28-03-2018 CU254_RS17520 ff2c190e47eba4c3424f23d9a3e1d08c 258 Pfam PF13649 Methyltransferase domain 45 135 1.3E-14 T 28-03-2018 CU254_RS17520 ff2c190e47eba4c3424f23d9a3e1d08c 258 Gene3D G3DSA:3.40.50.150 11 140 5.7E-18 T 28-03-2018 CU254_RS17520 ff2c190e47eba4c3424f23d9a3e1d08c 258 SUPERFAMILY SSF53335 6 226 5.43E-33 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS17520 ff2c190e47eba4c3424f23d9a3e1d08c 258 Gene3D G3DSA:2.20.130.10 146 204 6.4E-20 T 28-03-2018 CU254_RS14010 1cc3f7fe1923b8732caef17421e13ed0 334 Gene3D G3DSA:3.40.50.1980 39 164 4.6E-25 T 28-03-2018 CU254_RS14010 1cc3f7fe1923b8732caef17421e13ed0 334 Gene3D G3DSA:3.40.50.1980 165 334 2.9E-26 T 28-03-2018 CU254_RS14010 1cc3f7fe1923b8732caef17421e13ed0 334 SUPERFAMILY SSF53807 60 332 2.35E-50 T 28-03-2018 CU254_RS14010 1cc3f7fe1923b8732caef17421e13ed0 334 Pfam PF01497 Periplasmic binding protein 66 308 1.4E-23 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CU254_RS09855 99f08b1b115793ae9ad35c17eab8637f 283 Pfam PF01551 Peptidase family M23 57 148 3.3E-23 T 28-03-2018 IPR016047 Peptidase M23 CU254_RS09855 99f08b1b115793ae9ad35c17eab8637f 283 SUPERFAMILY SSF51261 66 148 1.26E-28 T 28-03-2018 IPR011055 Duplicated hybrid motif CU254_RS09855 99f08b1b115793ae9ad35c17eab8637f 283 Gene3D G3DSA:2.70.70.10 18 161 4.0E-27 T 28-03-2018 CU254_RS30885 d8d7b5cdd72a8acfd5893b7fff3cc293 269 Pfam PF12840 Helix-turn-helix domain 4 56 1.4E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS30885 d8d7b5cdd72a8acfd5893b7fff3cc293 269 SMART SM00418 3 81 6.4E-13 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS30885 d8d7b5cdd72a8acfd5893b7fff3cc293 269 Gene3D G3DSA:3.30.530.20 112 269 3.1E-28 T 28-03-2018 IPR023393 START-like domain CU254_RS30885 d8d7b5cdd72a8acfd5893b7fff3cc293 269 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 129 262 5.4E-17 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CU254_RS30885 d8d7b5cdd72a8acfd5893b7fff3cc293 269 SUPERFAMILY SSF55961 117 264 4.87E-27 T 28-03-2018 CU254_RS30885 d8d7b5cdd72a8acfd5893b7fff3cc293 269 Gene3D G3DSA:1.10.10.10 1 88 8.0E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS30885 d8d7b5cdd72a8acfd5893b7fff3cc293 269 SUPERFAMILY SSF46785 2 93 4.48E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS12730 ffc14da01d8a181591bee50c0a8b5f3a 484 SUPERFAMILY SSF142764 55 482 1.19E-66 T 28-03-2018 CU254_RS12730 ffc14da01d8a181591bee50c0a8b5f3a 484 Pfam PF17042 Putative nucleotide-binding of sugar-metabolising enzyme 312 474 1.1E-30 T 28-03-2018 IPR031475 Putative nucleotide-binding C-terminal domain CU254_RS12730 ffc14da01d8a181591bee50c0a8b5f3a 484 Gene3D G3DSA:3.40.50.10840 53 298 1.7E-67 T 28-03-2018 IPR010737 Putative sugar-binding, N-terminal domain CU254_RS12730 ffc14da01d8a181591bee50c0a8b5f3a 484 Pfam PF07005 Putative sugar-binding N-terminal domain 55 290 1.2E-56 T 28-03-2018 IPR010737 Putative sugar-binding, N-terminal domain CU254_RS35385 b5e6d737f0028565a4b13052abc32bdd 542 Gene3D G3DSA:1.10.560.10 372 514 9.8E-25 T 28-03-2018 IPR027413 GroEL-like equatorial domain CU254_RS35385 b5e6d737f0028565a4b13052abc32bdd 542 SUPERFAMILY SSF48592 6 133 9.16E-72 T 28-03-2018 CU254_RS35385 b5e6d737f0028565a4b13052abc32bdd 542 SUPERFAMILY SSF48592 404 519 9.16E-72 T 28-03-2018 CU254_RS35385 b5e6d737f0028565a4b13052abc32bdd 542 Gene3D G3DSA:1.10.560.10 1 180 8.9E-39 T 28-03-2018 IPR027413 GroEL-like equatorial domain CU254_RS35385 b5e6d737f0028565a4b13052abc32bdd 542 SUPERFAMILY SSF54849 137 202 3.66E-25 T 28-03-2018 CU254_RS35385 b5e6d737f0028565a4b13052abc32bdd 542 Gene3D G3DSA:3.50.7.10 181 371 2.2E-95 T 28-03-2018 IPR027409 GroEL-like apical domain CU254_RS35385 b5e6d737f0028565a4b13052abc32bdd 542 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 525 4.4E-247 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CU254_RS35385 b5e6d737f0028565a4b13052abc32bdd 542 Hamap MF_00600 60 kDa chaperonin [groL]. 1 540 41.033 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CU254_RS35385 b5e6d737f0028565a4b13052abc32bdd 542 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 523 3.9E-94 T 28-03-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 CU254_RS35385 b5e6d737f0028565a4b13052abc32bdd 542 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 28-03-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CU254_RS35385 b5e6d737f0028565a4b13052abc32bdd 542 PRINTS PR00298 60kDa chaperonin signature 348 373 2.6E-70 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CU254_RS35385 b5e6d737f0028565a4b13052abc32bdd 542 PRINTS PR00298 60kDa chaperonin signature 266 289 2.6E-70 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CU254_RS35385 b5e6d737f0028565a4b13052abc32bdd 542 PRINTS PR00298 60kDa chaperonin signature 82 109 2.6E-70 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CU254_RS35385 b5e6d737f0028565a4b13052abc32bdd 542 PRINTS PR00298 60kDa chaperonin signature 26 52 2.6E-70 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CU254_RS35385 b5e6d737f0028565a4b13052abc32bdd 542 PRINTS PR00298 60kDa chaperonin signature 396 417 2.6E-70 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CU254_RS35385 b5e6d737f0028565a4b13052abc32bdd 542 SUPERFAMILY SSF52029 184 374 6.88E-82 T 28-03-2018 IPR027409 GroEL-like apical domain CU254_RS00940 fa26955d222ecba2667ba6e435930f35 219 Pfam PF13419 Haloacid dehalogenase-like hydrolase 91 186 6.5E-14 T 28-03-2018 IPR023214 HAD-like domain CU254_RS00940 fa26955d222ecba2667ba6e435930f35 219 Gene3D G3DSA:1.10.150.240 16 73 5.4E-11 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CU254_RS00940 fa26955d222ecba2667ba6e435930f35 219 Gene3D G3DSA:3.40.50.1000 74 219 4.7E-27 T 28-03-2018 IPR023214 HAD-like domain CU254_RS00940 fa26955d222ecba2667ba6e435930f35 219 SUPERFAMILY SSF56784 3 212 1.14E-42 T 28-03-2018 IPR023214 HAD-like domain CU254_RS00940 fa26955d222ecba2667ba6e435930f35 219 TIGRFAM TIGR01428 HAD_type_II: haloacid dehalogenase, type II 2 192 9.4E-48 T 28-03-2018 IPR006328 L-2-Haloacid dehalogenase GO:0008152|GO:0019120 KEGG: 00361+3.8.1.2|KEGG: 00625+3.8.1.2|MetaCyc: PWY-7425 CU254_RS00940 fa26955d222ecba2667ba6e435930f35 219 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 101 114 2.8E-7 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CU254_RS00940 fa26955d222ecba2667ba6e435930f35 219 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 132 148 2.8E-7 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CU254_RS00940 fa26955d222ecba2667ba6e435930f35 219 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 150 170 2.8E-7 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CU254_RS00940 fa26955d222ecba2667ba6e435930f35 219 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 177 190 2.8E-7 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CU254_RS00940 fa26955d222ecba2667ba6e435930f35 219 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 116 186 3.7E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CU254_RS00940 fa26955d222ecba2667ba6e435930f35 219 TIGRFAM TIGR01493 HAD-SF-IA-v2: HAD hydrolase, family IA, variant 2 3 180 9.3E-16 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CU254_RS18070 e6f2690744442d29924fd90e58618180 389 Gene3D G3DSA:1.20.1250.20 3 189 5.1E-29 T 28-03-2018 CU254_RS18070 e6f2690744442d29924fd90e58618180 389 Pfam PF07690 Major Facilitator Superfamily 9 317 9.4E-41 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS18070 e6f2690744442d29924fd90e58618180 389 SUPERFAMILY SSF103473 3 379 2.09E-58 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS18070 e6f2690744442d29924fd90e58618180 389 Gene3D G3DSA:1.20.1250.20 190 389 5.3E-19 T 28-03-2018 CU254_RS04345 c56d69515255769d698d72ce8d43d8e7 254 Gene3D G3DSA:3.40.50.1980 134 254 6.2E-13 T 28-03-2018 CU254_RS04345 c56d69515255769d698d72ce8d43d8e7 254 Gene3D G3DSA:3.40.50.1980 2 126 9.3E-21 T 28-03-2018 CU254_RS04345 c56d69515255769d698d72ce8d43d8e7 254 Pfam PF01497 Periplasmic binding protein 23 209 1.9E-9 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CU254_RS04345 c56d69515255769d698d72ce8d43d8e7 254 SUPERFAMILY SSF53807 20 251 9.03E-36 T 28-03-2018 CU254_RS11165 1e9e80458bc0ff4d498860ae5c66d64c 542 SUPERFAMILY SSF53720 10 527 1.83E-122 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CU254_RS11165 1e9e80458bc0ff4d498860ae5c66d64c 542 Pfam PF00171 Aldehyde dehydrogenase family 56 522 4.3E-102 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CU254_RS11165 1e9e80458bc0ff4d498860ae5c66d64c 542 Gene3D G3DSA:3.40.309.10 313 505 8.8E-49 T 28-03-2018 CU254_RS11165 1e9e80458bc0ff4d498860ae5c66d64c 542 Gene3D G3DSA:3.40.605.10 38 312 2.1E-66 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CU254_RS11165 1e9e80458bc0ff4d498860ae5c66d64c 542 TIGRFAM TIGR01236 D1pyr5carbox1: 1-pyrroline-5-carboxylate dehydrogenase 11 541 4.7E-243 T 28-03-2018 IPR005931 Delta-1-pyrroline-5-carboxylate dehydrogenase GO:0003842|GO:0010133 KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853|Reactome: R-HSA-389661|Reactome: R-HSA-70688 CU254_RS11165 1e9e80458bc0ff4d498860ae5c66d64c 542 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 293 300 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CU254_RS11165 1e9e80458bc0ff4d498860ae5c66d64c 542 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 321 332 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CU254_RS27145 728168e018295d56ed79f00511245d70 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 5.8E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS27145 728168e018295d56ed79f00511245d70 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 5.8E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS27145 728168e018295d56ed79f00511245d70 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 5.8E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS27145 728168e018295d56ed79f00511245d70 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 5.8E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS27145 728168e018295d56ed79f00511245d70 254 Pfam PF00106 short chain dehydrogenase 7 191 7.9E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS27145 728168e018295d56ed79f00511245d70 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS27145 728168e018295d56ed79f00511245d70 254 Gene3D G3DSA:3.40.50.720 1 230 2.4E-45 T 28-03-2018 CU254_RS27145 728168e018295d56ed79f00511245d70 254 SUPERFAMILY SSF51735 1 199 1.81E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS04865 86e3897050d829c93348ea2b587dcf2a 431 Pfam PF01757 Acyltransferase family 18 347 3.4E-16 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CU254_RS35225 fb567e9c1c4c37f077f4e1e721b17880 354 Pfam PF04055 Radical SAM superfamily 42 203 1.4E-29 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CU254_RS35225 fb567e9c1c4c37f077f4e1e721b17880 354 SUPERFAMILY SSF102114 27 317 6.93E-76 T 28-03-2018 CU254_RS35225 fb567e9c1c4c37f077f4e1e721b17880 354 Pfam PF13353 4Fe-4S single cluster domain 44 128 6.2E-7 T 28-03-2018 CU254_RS35225 fb567e9c1c4c37f077f4e1e721b17880 354 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 43 54 - T 28-03-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 Reactome: R-HSA-947581 CU254_RS35225 fb567e9c1c4c37f077f4e1e721b17880 354 SMART SM00729 37 239 1.0E-4 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CU254_RS35225 fb567e9c1c4c37f077f4e1e721b17880 354 Pfam PF06463 Molybdenum Cofactor Synthesis C 210 336 1.4E-36 T 28-03-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 Reactome: R-HSA-947581 CU254_RS35225 fb567e9c1c4c37f077f4e1e721b17880 354 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 28 354 40.16 T 28-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 CU254_RS35225 fb567e9c1c4c37f077f4e1e721b17880 354 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 28 354 1.1E-112 T 28-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 CU254_RS35225 fb567e9c1c4c37f077f4e1e721b17880 354 Gene3D G3DSA:3.20.20.70 25 354 3.5E-83 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS33045 fcc83eb40f6a86a56c1e004026381ba5 286 Pfam PF12811 Bax inhibitor 1 like 46 285 4.7E-85 T 28-03-2018 IPR010539 Protein of unknown function UCP009160 CU254_RS33045 fcc83eb40f6a86a56c1e004026381ba5 286 PIRSF PIRSF009160 1 286 3.0E-78 T 28-03-2018 IPR010539 Protein of unknown function UCP009160 CU254_RS31625 b8795ea9cb76ca67ab381a752dada105 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 1.3E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS31625 b8795ea9cb76ca67ab381a752dada105 213 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 1.3E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS31625 b8795ea9cb76ca67ab381a752dada105 213 Gene3D G3DSA:1.10.10.60 8 70 7.8E-21 T 28-03-2018 CU254_RS31625 b8795ea9cb76ca67ab381a752dada105 213 SUPERFAMILY SSF46689 11 82 2.06E-19 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS31625 b8795ea9cb76ca67ab381a752dada105 213 SUPERFAMILY SSF48498 102 210 9.46E-14 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS31625 b8795ea9cb76ca67ab381a752dada105 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 68 7.8E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS31625 b8795ea9cb76ca67ab381a752dada105 213 Gene3D G3DSA:1.10.357.10 71 213 1.1E-17 T 28-03-2018 CU254_RS11360 ba3a9b6b68f51c37db6150be8b20df38 271 Pfam PF00144 Beta-lactamase 28 261 2.4E-36 T 28-03-2018 IPR001466 Beta-lactamase-related CU254_RS11360 ba3a9b6b68f51c37db6150be8b20df38 271 SUPERFAMILY SSF56601 7 265 5.14E-55 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CU254_RS11360 ba3a9b6b68f51c37db6150be8b20df38 271 Gene3D G3DSA:3.40.710.10 2 271 4.1E-57 T 28-03-2018 CU254_RS22715 846171c54c9300a0af7b34a5e0262c06 492 SUPERFAMILY SSF53067 249 478 3.24E-54 T 28-03-2018 CU254_RS22715 846171c54c9300a0af7b34a5e0262c06 492 Gene3D G3DSA:3.30.420.40 244 492 6.7E-57 T 28-03-2018 CU254_RS22715 846171c54c9300a0af7b34a5e0262c06 492 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 7 242 4.0E-45 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CU254_RS22715 846171c54c9300a0af7b34a5e0262c06 492 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 257 435 6.7E-30 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CU254_RS22715 846171c54c9300a0af7b34a5e0262c06 492 Gene3D G3DSA:3.30.420.40 5 243 4.6E-64 T 28-03-2018 CU254_RS22715 846171c54c9300a0af7b34a5e0262c06 492 PIRSF PIRSF000538 5 485 3.0E-120 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CU254_RS22715 846171c54c9300a0af7b34a5e0262c06 492 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 351 371 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CU254_RS22715 846171c54c9300a0af7b34a5e0262c06 492 SUPERFAMILY SSF53067 6 250 3.7E-55 T 28-03-2018 CU254_RS30990 6912f10bf83f0a1bcbe3b1315967be9b 135 Gene3D G3DSA:3.40.140.10 1 135 7.6E-26 T 28-03-2018 CU254_RS30990 6912f10bf83f0a1bcbe3b1315967be9b 135 SUPERFAMILY SSF102712 2 129 6.67E-26 T 28-03-2018 CU254_RS30990 6912f10bf83f0a1bcbe3b1315967be9b 135 Pfam PF14464 Prokaryotic homologs of the JAB domain 7 118 1.3E-26 T 28-03-2018 IPR028090 JAB domain, prokaryotic CU254_RS30990 6912f10bf83f0a1bcbe3b1315967be9b 135 SMART SM00232 1 131 8.7E-26 T 28-03-2018 IPR000555 JAB1/MPN/MOV34 metalloenzyme domain GO:0005515 CU254_RS19415 8d50a80d089378c5f94301602b4b4a8c 447 ProSitePatterns PS00217 Sugar transport proteins signature 2. 137 162 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CU254_RS19415 8d50a80d089378c5f94301602b4b4a8c 447 Gene3D G3DSA:1.20.1250.20 16 227 8.0E-20 T 28-03-2018 CU254_RS19415 8d50a80d089378c5f94301602b4b4a8c 447 Gene3D G3DSA:1.20.1250.20 229 442 1.1E-24 T 28-03-2018 CU254_RS19415 8d50a80d089378c5f94301602b4b4a8c 447 Pfam PF00083 Sugar (and other) transporter 28 240 2.1E-22 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CU254_RS19415 8d50a80d089378c5f94301602b4b4a8c 447 SUPERFAMILY SSF103473 20 436 3.66E-62 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS19415 8d50a80d089378c5f94301602b4b4a8c 447 Pfam PF07690 Major Facilitator Superfamily 294 434 2.7E-9 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS06165 ed5666a7c4d539de9a559497e0ce861f 511 Pfam PF00271 Helicase conserved C-terminal domain 236 338 1.3E-23 T 28-03-2018 IPR001650 Helicase, C-terminal CU254_RS06165 ed5666a7c4d539de9a559497e0ce861f 511 SMART SM00487 21 223 9.7E-50 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CU254_RS06165 ed5666a7c4d539de9a559497e0ce861f 511 SMART SM00490 257 338 4.5E-25 T 28-03-2018 IPR001650 Helicase, C-terminal CU254_RS06165 ed5666a7c4d539de9a559497e0ce861f 511 Gene3D G3DSA:3.40.50.300 229 511 2.2E-41 T 28-03-2018 CU254_RS06165 ed5666a7c4d539de9a559497e0ce861f 511 Pfam PF00270 DEAD/DEAH box helicase 26 191 2.8E-42 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CU254_RS06165 ed5666a7c4d539de9a559497e0ce861f 511 SUPERFAMILY SSF52540 75 358 1.12E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS06165 ed5666a7c4d539de9a559497e0ce861f 511 Gene3D G3DSA:3.40.50.300 1 228 5.6E-51 T 28-03-2018 CU254_RS38005 806fdcf6c7c428b6825a5a7648e1c75f 343 Pfam PF01116 Fructose-bisphosphate aldolase class-II 9 340 6.6E-83 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CU254_RS38005 806fdcf6c7c428b6825a5a7648e1c75f 343 SUPERFAMILY SSF51569 4 340 5.57E-98 T 28-03-2018 CU254_RS38005 806fdcf6c7c428b6825a5a7648e1c75f 343 PIRSF PIRSF001359 6 341 3.7E-67 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CU254_RS38005 806fdcf6c7c428b6825a5a7648e1c75f 343 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 10 340 1.8E-73 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CU254_RS38005 806fdcf6c7c428b6825a5a7648e1c75f 343 Gene3D G3DSA:3.20.20.70 1 343 4.5E-102 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS38005 806fdcf6c7c428b6825a5a7648e1c75f 343 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 158 169 - T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CU254_RS38005 806fdcf6c7c428b6825a5a7648e1c75f 343 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 86 97 - T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CU254_RS38005 806fdcf6c7c428b6825a5a7648e1c75f 343 TIGRFAM TIGR01520 FruBisAldo_II_A: fructose-bisphosphate aldolase, class II 3 339 1.9E-138 T 28-03-2018 IPR006411 Fructose-bisphosphate aldolase, class II, yeast/E. coli subtype GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 CU254_RS17910 786627bfeb9a3fcd607d989d0547fe3a 242 Pfam PF14011 EspG family 5 235 2.8E-41 T 28-03-2018 IPR025734 EspG family CU254_RS27010 3f2f09d48645788d7ba55cf6b8ee2166 216 Gene3D G3DSA:1.10.357.10 64 200 2.1E-26 T 28-03-2018 CU254_RS27010 3f2f09d48645788d7ba55cf6b8ee2166 216 Gene3D G3DSA:1.10.10.60 1 35 5.9E-11 T 28-03-2018 CU254_RS27010 3f2f09d48645788d7ba55cf6b8ee2166 216 SUPERFAMILY SSF46689 4 73 1.39E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS27010 3f2f09d48645788d7ba55cf6b8ee2166 216 Pfam PF13305 WHG domain 87 175 1.5E-12 T 28-03-2018 IPR025996 WHG domain CU254_RS27010 3f2f09d48645788d7ba55cf6b8ee2166 216 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 4.1E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS27010 3f2f09d48645788d7ba55cf6b8ee2166 216 SUPERFAMILY SSF48498 84 192 4.75E-21 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS27010 3f2f09d48645788d7ba55cf6b8ee2166 216 Gene3D G3DSA:1.10.260.40 36 63 9.9E-6 T 28-03-2018 CU254_RS02070 eae02e498bfc402548c92031d6421157 73 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 2 73 26.654 T 28-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 CU254_RS02070 eae02e498bfc402548c92031d6421157 73 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 4 72 2.9E-38 T 28-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 CU254_RS02070 eae02e498bfc402548c92031d6421157 73 SUPERFAMILY SSF50249 4 72 3.26E-27 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CU254_RS02070 eae02e498bfc402548c92031d6421157 73 Gene3D G3DSA:2.40.50.140 1 73 1.4E-37 T 28-03-2018 CU254_RS02070 eae02e498bfc402548c92031d6421157 73 Pfam PF01176 Translation initiation factor 1A / IF-1 8 71 2.3E-29 T 28-03-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 CU254_RS30515 ef5c73ac10e197ad86422898e982aefd 599 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 98 504 3.2E-53 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CU254_RS30515 ef5c73ac10e197ad86422898e982aefd 599 SUPERFAMILY SSF53850 37 206 2.53E-76 T 28-03-2018 CU254_RS30515 ef5c73ac10e197ad86422898e982aefd 599 SUPERFAMILY SSF53850 234 597 2.53E-76 T 28-03-2018 CU254_RS30515 ef5c73ac10e197ad86422898e982aefd 599 Gene3D G3DSA:3.40.190.10 232 335 1.7E-14 T 28-03-2018 CU254_RS30515 ef5c73ac10e197ad86422898e982aefd 599 PIRSF PIRSF002741 1 204 3.8E-14 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CU254_RS30515 ef5c73ac10e197ad86422898e982aefd 599 PIRSF PIRSF002741 218 599 1.1E-38 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CU254_RS30515 ef5c73ac10e197ad86422898e982aefd 599 Gene3D G3DSA:3.10.105.10 336 565 6.4E-34 T 28-03-2018 CU254_RS30515 ef5c73ac10e197ad86422898e982aefd 599 Gene3D G3DSA:3.90.76.10 58 205 1.1E-20 T 28-03-2018 CU254_RS32330 233c2d3a02787a51816a12feaa62155e 84 Pfam PF02467 Transcription factor WhiB 3 71 3.7E-25 T 28-03-2018 IPR034768 WhiB-like iron-sulfur binding domain CU254_RS32330 233c2d3a02787a51816a12feaa62155e 84 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 76 18.387 T 28-03-2018 IPR003482 Transcription factor WhiB CU254_RS19565 6fd03cb439234cbaffbf11970f0e69b4 128 Pfam PF14534 Domain of unknown function (DUF4440) 6 112 3.4E-20 T 28-03-2018 IPR027843 Domain of unknown function DUF4440 CU254_RS19565 6fd03cb439234cbaffbf11970f0e69b4 128 SUPERFAMILY SSF54427 3 120 2.43E-25 T 28-03-2018 IPR032710 NTF2-like domain CU254_RS19565 6fd03cb439234cbaffbf11970f0e69b4 128 Gene3D G3DSA:3.10.450.50 1 125 2.6E-26 T 28-03-2018 CU254_RS22255 71e2fe874e92d135b8d64c8a09a0b731 241 Pfam PF02224 Cytidylate kinase 2 219 8.8E-70 T 28-03-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 CU254_RS22255 71e2fe874e92d135b8d64c8a09a0b731 241 TIGRFAM TIGR00017 cmk: cytidylate kinase 2 214 1.2E-64 T 28-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 CU254_RS22255 71e2fe874e92d135b8d64c8a09a0b731 241 Gene3D G3DSA:3.40.50.300 1 221 4.3E-49 T 28-03-2018 CU254_RS22255 71e2fe874e92d135b8d64c8a09a0b731 241 Hamap MF_00238 Cytidylate kinase [cmk]. 1 223 29.455 T 28-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 CU254_RS22255 71e2fe874e92d135b8d64c8a09a0b731 241 SUPERFAMILY SSF52540 1 217 4.88E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS32825 c3e5bf0b886274d9b5e61e711f7a9a6f 507 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 94 108 4.0E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS32825 c3e5bf0b886274d9b5e61e711f7a9a6f 507 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 108 124 4.0E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS32825 c3e5bf0b886274d9b5e61e711f7a9a6f 507 SMART SM00345 75 134 4.6E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS32825 c3e5bf0b886274d9b5e61e711f7a9a6f 507 Pfam PF00392 Bacterial regulatory proteins, gntR family 73 134 7.0E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS32825 c3e5bf0b886274d9b5e61e711f7a9a6f 507 SUPERFAMILY SSF46785 70 138 7.74E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS32825 c3e5bf0b886274d9b5e61e711f7a9a6f 507 Pfam PF00155 Aminotransferase class I and II 172 503 3.0E-24 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CU254_RS32825 c3e5bf0b886274d9b5e61e711f7a9a6f 507 Gene3D G3DSA:3.40.640.10 181 388 1.5E-38 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS32825 c3e5bf0b886274d9b5e61e711f7a9a6f 507 Gene3D G3DSA:3.90.1150.10 389 506 4.3E-28 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS32825 c3e5bf0b886274d9b5e61e711f7a9a6f 507 SUPERFAMILY SSF53383 152 506 7.4E-84 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS32825 c3e5bf0b886274d9b5e61e711f7a9a6f 507 Gene3D G3DSA:1.10.10.10 55 136 1.8E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS13055 cd95e7386afc8e503101e564fc03027c 253 SUPERFAMILY SSF51735 7 250 3.51E-79 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS13055 cd95e7386afc8e503101e564fc03027c 253 Gene3D G3DSA:3.40.50.720 3 158 6.7E-47 T 28-03-2018 CU254_RS13055 cd95e7386afc8e503101e564fc03027c 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 4.6E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS13055 cd95e7386afc8e503101e564fc03027c 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 4.6E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS13055 cd95e7386afc8e503101e564fc03027c 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 4.6E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS13055 cd95e7386afc8e503101e564fc03027c 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 4.6E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS13055 cd95e7386afc8e503101e564fc03027c 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 4.6E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS13055 cd95e7386afc8e503101e564fc03027c 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 4.6E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS13055 cd95e7386afc8e503101e564fc03027c 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 9.2E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS13055 cd95e7386afc8e503101e564fc03027c 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 9.2E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS13055 cd95e7386afc8e503101e564fc03027c 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 9.2E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS13055 cd95e7386afc8e503101e564fc03027c 253 Gene3D G3DSA:3.40.50.720 159 252 3.0E-24 T 28-03-2018 CU254_RS13055 cd95e7386afc8e503101e564fc03027c 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 250 8.7E-62 T 28-03-2018 CU254_RS13055 cd95e7386afc8e503101e564fc03027c 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS13055 cd95e7386afc8e503101e564fc03027c 253 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 185 2.5E-5 T 28-03-2018 CU254_RS22475 1ee9206d2138b7f7199882b14c432aae 228 SUPERFAMILY SSF48371 15 228 1.21E-45 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 CU254_RS22475 1ee9206d2138b7f7199882b14c432aae 228 Gene3D G3DSA:1.20.1660.10 9 133 2.7E-27 T 28-03-2018 CU254_RS22475 1ee9206d2138b7f7199882b14c432aae 228 Gene3D G3DSA:1.25.40.290 134 228 5.9E-22 T 28-03-2018 CU254_RS22475 1ee9206d2138b7f7199882b14c432aae 228 Pfam PF08713 DNA alkylation repair enzyme 12 228 5.9E-57 T 28-03-2018 IPR014825 DNA alkylation repair enzyme CU254_RS11800 27e4bbc3da0c62861c7eeb0dc6975587 283 Gene3D G3DSA:1.10.10.10 17 143 6.9E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS11800 27e4bbc3da0c62861c7eeb0dc6975587 283 Pfam PF13551 Winged helix-turn helix 40 91 3.4E-7 T 28-03-2018 CU254_RS11800 27e4bbc3da0c62861c7eeb0dc6975587 283 SUPERFAMILY SSF46785 34 227 8.88E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS23385 3689111b02a8c421a8771cbc2a0f8aa5 399 Gene3D G3DSA:3.40.50.410 252 374 1.2E-8 T 28-03-2018 IPR002035 von Willebrand factor, type A CU254_RS23385 3689111b02a8c421a8771cbc2a0f8aa5 399 Pfam PF13203 Putative metallopeptidase domain 3 127 1.2E-17 T 28-03-2018 IPR025154 Putative metallopeptidase domain CU254_RS23385 3689111b02a8c421a8771cbc2a0f8aa5 399 Pfam PF13203 Putative metallopeptidase domain 156 257 3.7E-9 T 28-03-2018 IPR025154 Putative metallopeptidase domain CU254_RS23385 3689111b02a8c421a8771cbc2a0f8aa5 399 SUPERFAMILY SSF53300 259 362 6.49E-10 T 28-03-2018 IPR002035 von Willebrand factor, type A CU254_RS23385 3689111b02a8c421a8771cbc2a0f8aa5 399 Gene3D G3DSA:3.30.2010.10 2 80 5.7E-5 T 28-03-2018 CU254_RS23385 3689111b02a8c421a8771cbc2a0f8aa5 399 Pfam PF09967 VWA-like domain (DUF2201) 264 372 1.1E-12 T 28-03-2018 IPR018698 VWA-like domain CU254_RS03365 2fc4c7c375fb8a7005790edae853f5bb 263 TIGRFAM TIGR02067 his_9_HisN: histidinol-phosphatase 10 260 1.7E-91 T 28-03-2018 IPR011809 Histidinol-phosphate phosphatase, putative, inositol monophosphatase GO:0004401 KEGG: 00340+3.1.3.15 CU254_RS03365 2fc4c7c375fb8a7005790edae853f5bb 263 Gene3D G3DSA:3.40.190.80 157 263 1.3E-23 T 28-03-2018 CU254_RS03365 2fc4c7c375fb8a7005790edae853f5bb 263 PRINTS PR00377 Inositol monophosphatase superfamily signature 42 62 1.4E-21 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CU254_RS03365 2fc4c7c375fb8a7005790edae853f5bb 263 PRINTS PR00377 Inositol monophosphatase superfamily signature 212 236 1.4E-21 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CU254_RS03365 2fc4c7c375fb8a7005790edae853f5bb 263 PRINTS PR00377 Inositol monophosphatase superfamily signature 84 100 1.4E-21 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CU254_RS03365 2fc4c7c375fb8a7005790edae853f5bb 263 PRINTS PR00377 Inositol monophosphatase superfamily signature 64 80 1.4E-21 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CU254_RS03365 2fc4c7c375fb8a7005790edae853f5bb 263 Gene3D G3DSA:3.30.540.10 4 156 2.2E-46 T 28-03-2018 CU254_RS03365 2fc4c7c375fb8a7005790edae853f5bb 263 SUPERFAMILY SSF56655 6 261 7.2E-74 T 28-03-2018 CU254_RS03365 2fc4c7c375fb8a7005790edae853f5bb 263 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 215 229 - T 28-03-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 CU254_RS03365 2fc4c7c375fb8a7005790edae853f5bb 263 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 84 97 - T 28-03-2018 IPR020583 Inositol monophosphatase, metal-binding site CU254_RS03365 2fc4c7c375fb8a7005790edae853f5bb 263 Pfam PF00459 Inositol monophosphatase family 11 249 2.5E-49 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CU254_RS03080 2e12e115913abf3b62912f28ca6933e9 431 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 5 426 24.241 T 28-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 CU254_RS03080 2e12e115913abf3b62912f28ca6933e9 431 SUPERFAMILY SSF52954 334 426 1.66E-18 T 28-03-2018 IPR004154 Anticodon-binding CU254_RS03080 2e12e115913abf3b62912f28ca6933e9 431 Gene3D G3DSA:3.30.930.10 3 328 2.8E-67 T 28-03-2018 CU254_RS03080 2e12e115913abf3b62912f28ca6933e9 431 SUPERFAMILY SSF55681 10 320 5.77E-63 T 28-03-2018 CU254_RS03080 2e12e115913abf3b62912f28ca6933e9 431 Pfam PF03129 Anticodon binding domain 337 426 2.4E-15 T 28-03-2018 IPR004154 Anticodon-binding CU254_RS03080 2e12e115913abf3b62912f28ca6933e9 431 Gene3D G3DSA:3.40.50.800 332 429 2.5E-20 T 28-03-2018 IPR004154 Anticodon-binding CU254_RS03080 2e12e115913abf3b62912f28ca6933e9 431 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 9 415 1.3E-102 T 28-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 CU254_RS03080 2e12e115913abf3b62912f28ca6933e9 431 PIRSF PIRSF001549 3 428 2.3E-108 T 28-03-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 CU254_RS03080 2e12e115913abf3b62912f28ca6933e9 431 Pfam PF13393 Histidyl-tRNA synthetase 12 313 4.0E-40 T 28-03-2018 CU254_RS34205 fb7aa7e5f0d5dbf64fdfd750ef719f2c 223 Pfam PF09837 Uncharacterized protein conserved in bacteria (DUF2064) 41 167 9.4E-24 T 28-03-2018 IPR018641 Transferase 1, rSAM/selenodomain-associated CU254_RS34205 fb7aa7e5f0d5dbf64fdfd750ef719f2c 223 SUPERFAMILY SSF53448 7 208 3.88E-18 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS34205 fb7aa7e5f0d5dbf64fdfd750ef719f2c 223 Gene3D G3DSA:3.90.550.10 3 193 9.2E-12 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS12570 bb1ec3b2b6d4908bf1ed8c3e779dc39c 453 Gene3D G3DSA:3.90.1300.10 1 453 8.6E-118 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS12570 bb1ec3b2b6d4908bf1ed8c3e779dc39c 453 ProSitePatterns PS00571 Amidases signature. 150 181 - T 28-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CU254_RS12570 bb1ec3b2b6d4908bf1ed8c3e779dc39c 453 SUPERFAMILY SSF75304 2 451 5.89E-115 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS12570 bb1ec3b2b6d4908bf1ed8c3e779dc39c 453 Pfam PF01425 Amidase 22 441 3.3E-98 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS20475 fdda0e6c4fd7517790e4803d524131a9 59 Gene3D G3DSA:3.90.820.10 1 58 2.8E-25 T 28-03-2018 CU254_RS20475 fdda0e6c4fd7517790e4803d524131a9 59 SMART SM00923 1 43 1.5E-17 T 28-03-2018 IPR005153 MbtH-like protein CU254_RS20475 fdda0e6c4fd7517790e4803d524131a9 59 Pfam PF03621 MbtH-like protein 2 43 2.9E-20 T 28-03-2018 IPR005153 MbtH-like protein CU254_RS20475 fdda0e6c4fd7517790e4803d524131a9 59 SUPERFAMILY SSF160582 1 56 3.01E-23 T 28-03-2018 CU254_RS14110 f98f62358be7a3c4b7055fdc2ae47d39 188 Gene3D G3DSA:1.10.10.60 8 61 7.3E-17 T 28-03-2018 CU254_RS14110 f98f62358be7a3c4b7055fdc2ae47d39 188 Gene3D G3DSA:1.10.357.10 62 186 7.6E-14 T 28-03-2018 CU254_RS14110 f98f62358be7a3c4b7055fdc2ae47d39 188 SUPERFAMILY SSF46689 10 56 2.46E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS14110 f98f62358be7a3c4b7055fdc2ae47d39 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 55 5.2E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS14110 f98f62358be7a3c4b7055fdc2ae47d39 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 1.6E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS14110 f98f62358be7a3c4b7055fdc2ae47d39 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 1.6E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS30450 80b8eab35ab10c58f0b42b7260466578 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 124 144 5.6E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS30450 80b8eab35ab10c58f0b42b7260466578 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 74 89 5.6E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS30450 80b8eab35ab10c58f0b42b7260466578 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 57 73 5.6E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS30450 80b8eab35ab10c58f0b42b7260466578 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 93 109 5.6E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS30450 80b8eab35ab10c58f0b42b7260466578 151 SMART SM00347 31 134 8.0E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS30450 80b8eab35ab10c58f0b42b7260466578 151 Pfam PF12802 MarR family 37 97 3.4E-8 T 28-03-2018 CU254_RS30450 80b8eab35ab10c58f0b42b7260466578 151 Gene3D G3DSA:1.10.10.10 2 151 6.3E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS30450 80b8eab35ab10c58f0b42b7260466578 151 SUPERFAMILY SSF46785 4 148 4.16E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS29995 bea6b7087fec98209a0a318af5ab3f42 279 Pfam PF01636 Phosphotransferase enzyme family 41 240 7.0E-21 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CU254_RS29995 bea6b7087fec98209a0a318af5ab3f42 279 SUPERFAMILY SSF56112 7 221 8.67E-25 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS29995 bea6b7087fec98209a0a318af5ab3f42 279 Gene3D G3DSA:1.10.510.10 51 273 2.3E-17 T 28-03-2018 CU254_RS31855 95d6fa792869d2136c03bc3cc0af9a8f 139 Pfam PF12802 MarR family 31 89 1.1E-12 T 28-03-2018 CU254_RS31855 95d6fa792869d2136c03bc3cc0af9a8f 139 SUPERFAMILY SSF46785 4 122 5.82E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS31855 95d6fa792869d2136c03bc3cc0af9a8f 139 SMART SM00347 25 124 2.7E-13 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS31855 95d6fa792869d2136c03bc3cc0af9a8f 139 Gene3D G3DSA:1.10.10.10 1 134 9.4E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS17145 bddbc7d6021e704db7a27f9ec1db8c04 312 Gene3D G3DSA:1.10.3720.10 76 307 4.2E-46 T 28-03-2018 CU254_RS17145 bddbc7d6021e704db7a27f9ec1db8c04 312 SUPERFAMILY SSF161098 71 296 1.83E-62 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS17145 bddbc7d6021e704db7a27f9ec1db8c04 312 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 299 8.5E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS17145 bddbc7d6021e704db7a27f9ec1db8c04 312 Gene3D G3DSA:1.20.58.370 3 57 4.9E-6 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain CU254_RS19030 479ec72ef2209a3d640d9725a897fc32 341 Pfam PF00589 Phage integrase family 128 302 3.4E-19 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CU254_RS19030 479ec72ef2209a3d640d9725a897fc32 341 Gene3D G3DSA:1.10.443.10 125 312 1.9E-33 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CU254_RS19030 479ec72ef2209a3d640d9725a897fc32 341 Gene3D G3DSA:1.10.150.130 3 124 5.2E-15 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CU254_RS19030 479ec72ef2209a3d640d9725a897fc32 341 SUPERFAMILY SSF56349 8 311 2.88E-38 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CU254_RS28590 94942af7b65a1e4c109ad3e365b53b03 368 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 227 323 9.8E-15 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CU254_RS28590 94942af7b65a1e4c109ad3e365b53b03 368 SUPERFAMILY SSF53597 2 214 6.54E-46 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CU254_RS28590 94942af7b65a1e4c109ad3e365b53b03 368 SUPERFAMILY SSF53927 223 350 6.19E-23 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CU254_RS28590 94942af7b65a1e4c109ad3e365b53b03 368 Gene3D G3DSA:3.40.430.10 1 218 9.8E-60 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CU254_RS28590 94942af7b65a1e4c109ad3e365b53b03 368 Pfam PF01872 RibD C-terminal domain 5 210 2.6E-43 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CU254_RS28590 94942af7b65a1e4c109ad3e365b53b03 368 Gene3D G3DSA:3.40.140.10 219 362 9.3E-23 T 28-03-2018 CU254_RS26305 713051b582eaf7d6a7a9da9b0edecb1b 313 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 11 171 2.1E-16 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS26305 713051b582eaf7d6a7a9da9b0edecb1b 313 Gene3D G3DSA:3.10.450.50 163 307 1.4E-19 T 28-03-2018 CU254_RS26305 713051b582eaf7d6a7a9da9b0edecb1b 313 Gene3D G3DSA:1.10.1740.10 2 79 4.5E-15 T 28-03-2018 CU254_RS26305 713051b582eaf7d6a7a9da9b0edecb1b 313 SUPERFAMILY SSF88659 115 171 8.22E-11 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS26305 713051b582eaf7d6a7a9da9b0edecb1b 313 SUPERFAMILY SSF54427 183 305 1.04E-12 T 28-03-2018 IPR032710 NTF2-like domain CU254_RS26305 713051b582eaf7d6a7a9da9b0edecb1b 313 Gene3D G3DSA:1.10.10.10 80 162 2.6E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS26305 713051b582eaf7d6a7a9da9b0edecb1b 313 SUPERFAMILY SSF88946 10 94 7.85E-14 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS26305 713051b582eaf7d6a7a9da9b0edecb1b 313 Pfam PF08281 Sigma-70, region 4 119 170 1.2E-11 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS26305 713051b582eaf7d6a7a9da9b0edecb1b 313 Pfam PF04542 Sigma-70 region 2 15 79 4.1E-11 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS34665 d8001cf8225b3a044916ffc5a8020fb6 525 Gene3D G3DSA:2.30.40.10 463 525 1.8E-10 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS34665 d8001cf8225b3a044916ffc5a8020fb6 525 SUPERFAMILY SSF51556 51 108 1.2E-34 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS34665 d8001cf8225b3a044916ffc5a8020fb6 525 SUPERFAMILY SSF51556 181 486 1.2E-34 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS34665 d8001cf8225b3a044916ffc5a8020fb6 525 SUPERFAMILY SSF51338 485 521 3.67E-15 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS34665 d8001cf8225b3a044916ffc5a8020fb6 525 SUPERFAMILY SSF51338 2 52 3.67E-15 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS34665 d8001cf8225b3a044916ffc5a8020fb6 525 Gene3D G3DSA:3.20.20.140 62 462 2.5E-46 T 28-03-2018 CU254_RS34665 d8001cf8225b3a044916ffc5a8020fb6 525 Pfam PF07969 Amidohydrolase family 42 520 7.1E-89 T 28-03-2018 IPR013108 Amidohydrolase 3 CU254_RS34665 d8001cf8225b3a044916ffc5a8020fb6 525 Gene3D G3DSA:2.30.40.10 2 61 4.6E-12 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS18790 b57477c382c23820caad0551b6d42880 387 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 16 155 1.5E-27 T 28-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CU254_RS18790 b57477c382c23820caad0551b6d42880 387 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 203 367 3.2E-35 T 28-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CU254_RS18790 b57477c382c23820caad0551b6d42880 387 Gene3D G3DSA:3.40.50.2000 11 189 1.9E-25 T 28-03-2018 CU254_RS18790 b57477c382c23820caad0551b6d42880 387 Gene3D G3DSA:3.40.50.2000 190 359 4.6E-33 T 28-03-2018 CU254_RS18790 b57477c382c23820caad0551b6d42880 387 SUPERFAMILY SSF53756 15 375 1.91E-88 T 28-03-2018 CU254_RS18790 b57477c382c23820caad0551b6d42880 387 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 16 375 29.651 T 28-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CU254_RS15695 d413044296a9e61e50ebe5e831fc1e70 333 Gene3D G3DSA:3.40.50.720 140 295 7.4E-20 T 28-03-2018 CU254_RS15695 d413044296a9e61e50ebe5e831fc1e70 333 Gene3D G3DSA:3.90.180.10 8 139 1.9E-17 T 28-03-2018 CU254_RS15695 d413044296a9e61e50ebe5e831fc1e70 333 Pfam PF00107 Zinc-binding dehydrogenase 160 283 1.7E-11 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CU254_RS15695 d413044296a9e61e50ebe5e831fc1e70 333 SUPERFAMILY SSF51735 120 294 1.55E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS15695 d413044296a9e61e50ebe5e831fc1e70 333 SMART SM00829 17 325 0.0018 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CU254_RS15695 d413044296a9e61e50ebe5e831fc1e70 333 TIGRFAM TIGR02823 oxido_YhdH: putative quinone oxidoreductase, YhdH/YhfP family 17 327 1.3E-107 T 28-03-2018 IPR014188 Acrylyl-CoA reductase AcuI CU254_RS15695 d413044296a9e61e50ebe5e831fc1e70 333 SUPERFAMILY SSF50129 18 146 1.05E-29 T 28-03-2018 IPR011032 GroES-like CU254_RS10915 92d4f2e7ba6e2eb42777bb535bfdaa74 682 Pfam PF13520 Amino acid permease 51 457 6.8E-24 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CU254_RS08765 c4bf0adc9ee1dac24c09147528b66784 595 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CU254_RS08765 c4bf0adc9ee1dac24c09147528b66784 595 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 156 185 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CU254_RS08765 c4bf0adc9ee1dac24c09147528b66784 595 SUPERFAMILY SSF47005 276 318 1.7E-11 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CU254_RS08765 c4bf0adc9ee1dac24c09147528b66784 595 Gene3D G3DSA:4.10.320.10 285 327 3.8E-20 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CU254_RS08765 c4bf0adc9ee1dac24c09147528b66784 595 Pfam PF02817 e3 binding domain 281 315 1.5E-14 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CU254_RS08765 c4bf0adc9ee1dac24c09147528b66784 595 TIGRFAM TIGR02927 SucB_Actino: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase 1 595 2.3E-271 T 28-03-2018 IPR014276 2-oxoglutarate dehydrogenase, E2 component KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12 CU254_RS08765 c4bf0adc9ee1dac24c09147528b66784 595 Pfam PF00364 Biotin-requiring enzyme 5 76 3.9E-22 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CU254_RS08765 c4bf0adc9ee1dac24c09147528b66784 595 Pfam PF00364 Biotin-requiring enzyme 133 205 2.8E-21 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CU254_RS08765 c4bf0adc9ee1dac24c09147528b66784 595 SUPERFAMILY SSF51230 1 96 3.53E-27 T 28-03-2018 IPR011053 Single hybrid motif CU254_RS08765 c4bf0adc9ee1dac24c09147528b66784 595 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 359 586 3.4E-70 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CU254_RS08765 c4bf0adc9ee1dac24c09147528b66784 595 SUPERFAMILY SSF51230 132 225 4.32E-27 T 28-03-2018 IPR011053 Single hybrid motif CU254_RS08765 c4bf0adc9ee1dac24c09147528b66784 595 Gene3D G3DSA:3.90.1170.30 46 174 2.6E-34 T 28-03-2018 CU254_RS08765 c4bf0adc9ee1dac24c09147528b66784 595 Gene3D G3DSA:3.90.1170.30 175 284 2.8E-8 T 28-03-2018 CU254_RS08765 c4bf0adc9ee1dac24c09147528b66784 595 Gene3D G3DSA:3.90.1170.30 2 45 7.0E-19 T 28-03-2018 CU254_RS08765 c4bf0adc9ee1dac24c09147528b66784 595 Gene3D G3DSA:3.30.559.10 341 588 1.1E-75 T 28-03-2018 CU254_RS08765 c4bf0adc9ee1dac24c09147528b66784 595 SUPERFAMILY SSF52777 348 586 5.78E-74 T 28-03-2018 CU254_RS26385 3da614e14c98a90184b14ad216d419e7 249 TIGRFAM TIGR03943 TIGR03943: TIGR03943 family protein 23 247 8.1E-53 T 28-03-2018 IPR015402 Protein of unknown function DUF1980 CU254_RS26385 3da614e14c98a90184b14ad216d419e7 249 Pfam PF09323 Domain of unknown function (DUF1980) 8 111 1.1E-8 T 28-03-2018 IPR015402 Protein of unknown function DUF1980 CU254_RS34170 0cb17bbe4e7f4742d2c2b2faece06a0d 166 SMART SM00852 12 156 5.7E-18 T 28-03-2018 IPR001453 MoaB/Mog domain CU254_RS34170 0cb17bbe4e7f4742d2c2b2faece06a0d 166 Gene3D G3DSA:3.40.980.10 3 164 1.2E-31 T 28-03-2018 IPR001453 MoaB/Mog domain CU254_RS34170 0cb17bbe4e7f4742d2c2b2faece06a0d 166 Pfam PF00994 Probable molybdopterin binding domain 13 150 1.6E-26 T 28-03-2018 IPR001453 MoaB/Mog domain CU254_RS34170 0cb17bbe4e7f4742d2c2b2faece06a0d 166 SUPERFAMILY SSF53218 10 160 2.75E-35 T 28-03-2018 IPR001453 MoaB/Mog domain CU254_RS34170 0cb17bbe4e7f4742d2c2b2faece06a0d 166 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 10 149 2.8E-28 T 28-03-2018 IPR001453 MoaB/Mog domain CU254_RS08600 a6695a9b58b2ba59e3b79863b9eb88e4 403 Gene3D G3DSA:3.20.20.70 32 403 6.2E-98 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS08600 a6695a9b58b2ba59e3b79863b9eb88e4 403 PIRSF PIRSF000138 19 403 2.0E-124 T 28-03-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 CU254_RS08600 a6695a9b58b2ba59e3b79863b9eb88e4 403 SUPERFAMILY SSF51395 34 399 1.73E-95 T 28-03-2018 CU254_RS08600 a6695a9b58b2ba59e3b79863b9eb88e4 403 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 298 304 - T 28-03-2018 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 CU254_RS08600 a6695a9b58b2ba59e3b79863b9eb88e4 403 Pfam PF01070 FMN-dependent dehydrogenase 43 400 2.1E-126 T 28-03-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 CU254_RS27055 c6f46e4312f8f87ee6bb8d6b8d3326e4 603 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 80 235 4.1E-31 T 28-03-2018 CU254_RS27055 c6f46e4312f8f87ee6bb8d6b8d3326e4 603 PRINTS PR00342 Rhesus blood group protein signature 175 192 9.5E-5 T 28-03-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 CU254_RS27055 c6f46e4312f8f87ee6bb8d6b8d3326e4 603 PRINTS PR00342 Rhesus blood group protein signature 392 405 9.5E-5 T 28-03-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 CU254_RS27055 c6f46e4312f8f87ee6bb8d6b8d3326e4 603 PRINTS PR00342 Rhesus blood group protein signature 357 379 9.5E-5 T 28-03-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 CU254_RS27055 c6f46e4312f8f87ee6bb8d6b8d3326e4 603 PRINTS PR00342 Rhesus blood group protein signature 132 150 9.5E-5 T 28-03-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 CU254_RS27055 c6f46e4312f8f87ee6bb8d6b8d3326e4 603 PRINTS PR00342 Rhesus blood group protein signature 296 311 9.5E-5 T 28-03-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 CU254_RS36915 c0ea2f304a832ba536fb7114f1476bdc 487 Gene3D G3DSA:3.30.2010.10 73 166 2.4E-12 T 28-03-2018 CU254_RS36915 c0ea2f304a832ba536fb7114f1476bdc 487 Pfam PF01435 Peptidase family M48 79 309 1.6E-13 T 28-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CU254_RS01930 aa343b2037a86506b22600f259595b9f 156 PIRSF PIRSF002122 5 156 1.8E-56 T 28-03-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 CU254_RS01930 aa343b2037a86506b22600f259595b9f 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 1.5E-59 T 28-03-2018 IPR023798 Ribosomal protein S7 domain CU254_RS01930 aa343b2037a86506b22600f259595b9f 156 SUPERFAMILY SSF47973 1 149 7.59E-57 T 28-03-2018 IPR023798 Ribosomal protein S7 domain CU254_RS01930 aa343b2037a86506b22600f259595b9f 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 28-03-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS01930 aa343b2037a86506b22600f259595b9f 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 1.2E-64 T 28-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 CU254_RS01930 aa343b2037a86506b22600f259595b9f 156 Gene3D G3DSA:1.10.455.10 6 156 1.8E-55 T 28-03-2018 IPR023798 Ribosomal protein S7 domain CU254_RS01930 aa343b2037a86506b22600f259595b9f 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 34.795 T 28-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 CU254_RS03320 dae0f8de4bd6ca2d8196217e776aff25 975 Gene3D G3DSA:1.10.10.10 12 104 1.3E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS03320 dae0f8de4bd6ca2d8196217e776aff25 975 Gene3D G3DSA:1.25.40.10 105 261 1.5E-24 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS03320 dae0f8de4bd6ca2d8196217e776aff25 975 Pfam PF03704 Bacterial transcriptional activator domain 104 238 4.6E-36 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CU254_RS03320 dae0f8de4bd6ca2d8196217e776aff25 975 Pfam PF13191 AAA ATPase domain 251 388 7.4E-16 T 28-03-2018 CU254_RS03320 dae0f8de4bd6ca2d8196217e776aff25 975 SMART SM01043 103 238 3.1E-49 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CU254_RS03320 dae0f8de4bd6ca2d8196217e776aff25 975 SMART SM00862 17 96 1.1E-8 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS03320 dae0f8de4bd6ca2d8196217e776aff25 975 Gene3D G3DSA:1.25.40.120 448 964 6.6E-6 T 28-03-2018 CU254_RS03320 dae0f8de4bd6ca2d8196217e776aff25 975 SUPERFAMILY SSF48452 100 248 5.81E-31 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS03320 dae0f8de4bd6ca2d8196217e776aff25 975 SUPERFAMILY SSF46894 4 96 3.12E-12 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS03320 dae0f8de4bd6ca2d8196217e776aff25 975 Pfam PF00486 Transcriptional regulatory protein, C terminal 24 96 6.4E-10 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS03320 dae0f8de4bd6ca2d8196217e776aff25 975 SUPERFAMILY SSF52540 248 458 6.93E-15 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS03320 dae0f8de4bd6ca2d8196217e776aff25 975 Gene3D G3DSA:3.40.50.300 262 418 1.3E-9 T 28-03-2018 CU254_RS19990 edc94d75bff340498e9a480d01cc0953 374 Pfam PF07687 Peptidase dimerisation domain 170 257 9.8E-5 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CU254_RS19990 edc94d75bff340498e9a480d01cc0953 374 Pfam PF01546 Peptidase family M20/M25/M40 83 335 1.0E-6 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CU254_RS19990 edc94d75bff340498e9a480d01cc0953 374 Gene3D G3DSA:3.40.630.10 2 373 2.7E-52 T 28-03-2018 CU254_RS19990 edc94d75bff340498e9a480d01cc0953 374 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 19 343 5.0E-57 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CU254_RS19990 edc94d75bff340498e9a480d01cc0953 374 SUPERFAMILY SSF55031 170 273 5.63E-20 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CU254_RS19990 edc94d75bff340498e9a480d01cc0953 374 PIRSF PIRSF037226 1 373 1.4E-132 T 28-03-2018 IPR017144 Peptidase M20A, amidohydrolase, predicted CU254_RS19990 edc94d75bff340498e9a480d01cc0953 374 SUPERFAMILY SSF53187 10 180 5.54E-58 T 28-03-2018 CU254_RS19990 edc94d75bff340498e9a480d01cc0953 374 SUPERFAMILY SSF53187 280 371 5.54E-58 T 28-03-2018 CU254_RS01570 80e75d3148c1b41f25a78da521cda6cc 182 SUPERFAMILY SSF51182 1 177 2.05E-57 T 28-03-2018 IPR011051 RmlC-like cupin domain CU254_RS01570 80e75d3148c1b41f25a78da521cda6cc 182 Gene3D G3DSA:2.60.120.10 1 182 4.2E-58 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS01570 80e75d3148c1b41f25a78da521cda6cc 182 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 8 164 1.0E-46 T 28-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 CU254_RS01570 80e75d3148c1b41f25a78da521cda6cc 182 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 7 174 4.1E-53 T 28-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 CU254_RS14510 08c20cc8259ced89ef8c3fa9a3cd846b 477 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 365 447 2.7E-12 T 28-03-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain CU254_RS14510 08c20cc8259ced89ef8c3fa9a3cd846b 477 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 92 269 1.1E-31 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CU254_RS14510 08c20cc8259ced89ef8c3fa9a3cd846b 477 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 92 269 9.4E-23 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CU254_RS13915 eeafd41de96d222a1fbfa3ac99630cb8 636 Gene3D G3DSA:1.50.10.20 43 297 5.4E-73 T 28-03-2018 CU254_RS13915 eeafd41de96d222a1fbfa3ac99630cb8 636 Pfam PF13243 Squalene-hopene cyclase C-terminal domain 317 632 1.4E-135 T 28-03-2018 IPR032696 Squalene cyclase, C-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 CU254_RS13915 eeafd41de96d222a1fbfa3ac99630cb8 636 TIGRFAM TIGR01507 hopene_cyclase: squalene-hopene cyclase 10 632 1.6E-227 T 28-03-2018 IPR006400 Squalene hopene cyclase GO:0016866|GO:0019746 KEGG: 00030+4.2.1.12|KEGG: 00909+4.2.1.129+5.4.99.17|MetaCyc: PWY-6098|MetaCyc: PWY-7072 CU254_RS13915 eeafd41de96d222a1fbfa3ac99630cb8 636 Gene3D G3DSA:1.50.10.20 298 634 4.9E-113 T 28-03-2018 CU254_RS13915 eeafd41de96d222a1fbfa3ac99630cb8 636 SUPERFAMILY SSF48239 215 270 6.43E-109 T 28-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CU254_RS13915 eeafd41de96d222a1fbfa3ac99630cb8 636 SUPERFAMILY SSF48239 314 633 6.43E-109 T 28-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CU254_RS13915 eeafd41de96d222a1fbfa3ac99630cb8 636 Pfam PF13249 Squalene-hopene cyclase N-terminal domain 23 303 1.8E-114 T 28-03-2018 IPR032697 Squalene cyclase, N-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 CU254_RS13915 eeafd41de96d222a1fbfa3ac99630cb8 636 TIGRFAM TIGR01787 squalene_cyclas: squalene/oxidosqualene cyclases 21 632 4.6E-180 T 28-03-2018 IPR018333 Squalene cyclase GO:0016866 Reactome: R-HSA-191273|Reactome: R-HSA-2426168 CU254_RS13915 eeafd41de96d222a1fbfa3ac99630cb8 636 SUPERFAMILY SSF48239 46 302 7.32E-71 T 28-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CU254_RS11180 6787eba11646b6704de3cde8d8e7ea62 79 ProDom PD062385 SCO7189 RV0898C/MT0921.1 MB0922C 5 79 2.0E-8 T 28-03-2018 IPR020311 Uncharacterised protein family, Rv0898c CU254_RS11180 6787eba11646b6704de3cde8d8e7ea62 79 Pfam PF10944 Protein of unknown function (DUF2630) 4 79 2.0E-30 T 28-03-2018 IPR020311 Uncharacterised protein family, Rv0898c CU254_RS30190 66dd865b84f4bb98fce54c3a60a8a65f 310 Pfam PF00561 alpha/beta hydrolase fold 31 284 8.0E-23 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS30190 66dd865b84f4bb98fce54c3a60a8a65f 310 PIRSF PIRSF005539 3 304 1.3E-109 T 28-03-2018 IPR005945 Proline-specific peptidase GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CU254_RS30190 66dd865b84f4bb98fce54c3a60a8a65f 310 Gene3D G3DSA:3.40.50.1820 7 306 1.0E-60 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS30190 66dd865b84f4bb98fce54c3a60a8a65f 310 SUPERFAMILY SSF53474 11 296 3.35E-58 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS30190 66dd865b84f4bb98fce54c3a60a8a65f 310 TIGRFAM TIGR01250 pro_imino_pep_2: proline-specific peptidase 10 295 1.1E-72 T 28-03-2018 IPR005945 Proline-specific peptidase GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CU254_RS30190 66dd865b84f4bb98fce54c3a60a8a65f 310 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 60 71 8.9E-10 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CU254_RS30190 66dd865b84f4bb98fce54c3a60a8a65f 310 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 33 41 8.9E-10 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CU254_RS30190 66dd865b84f4bb98fce54c3a60a8a65f 310 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 106 120 8.9E-10 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CU254_RS20415 b56776728416578df38316925bb677c6 420 Gene3D G3DSA:3.20.20.70 44 416 3.5E-101 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS20415 b56776728416578df38316925bb677c6 420 SUPERFAMILY SSF51395 46 411 2.32E-96 T 28-03-2018 CU254_RS20415 b56776728416578df38316925bb677c6 420 Pfam PF01070 FMN-dependent dehydrogenase 55 411 4.5E-125 T 28-03-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 CU254_RS20415 b56776728416578df38316925bb677c6 420 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 310 316 - T 28-03-2018 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 CU254_RS20415 b56776728416578df38316925bb677c6 420 PIRSF PIRSF000138 27 415 1.5E-125 T 28-03-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 CU254_RS32305 e86229611d303ad943df3ee3b9c4026c 196 Gene3D G3DSA:3.40.50.1240 2 196 9.7E-49 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CU254_RS32305 e86229611d303ad943df3ee3b9c4026c 196 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 189 7.1E-49 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CU254_RS32305 e86229611d303ad943df3ee3b9c4026c 196 PIRSF PIRSF000709 2 163 7.3E-9 T 28-03-2018 CU254_RS32305 e86229611d303ad943df3ee3b9c4026c 196 SUPERFAMILY SSF53254 4 194 1.94E-51 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CU254_RS32305 e86229611d303ad943df3ee3b9c4026c 196 SMART SM00855 4 151 5.3E-23 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CU254_RS12850 a88ee63a4574ec72339b78e158a5e552 331 SMART SM00861 4 178 7.8E-53 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CU254_RS12850 a88ee63a4574ec72339b78e158a5e552 331 SUPERFAMILY SSF52922 188 324 1.44E-31 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CU254_RS12850 a88ee63a4574ec72339b78e158a5e552 331 Pfam PF02779 Transketolase, pyrimidine binding domain 6 175 1.4E-42 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CU254_RS12850 a88ee63a4574ec72339b78e158a5e552 331 Gene3D G3DSA:3.40.50.920 195 325 6.9E-26 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CU254_RS12850 a88ee63a4574ec72339b78e158a5e552 331 SUPERFAMILY SSF52518 2 204 7.5E-63 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS12850 a88ee63a4574ec72339b78e158a5e552 331 Gene3D G3DSA:3.40.50.970 2 194 8.3E-60 T 28-03-2018 CU254_RS12850 a88ee63a4574ec72339b78e158a5e552 331 Pfam PF02780 Transketolase, C-terminal domain 194 316 1.6E-27 T 28-03-2018 IPR033248 Transketolase, C-terminal domain CU254_RS10185 c23d23c764c561e2de833bba8c82bfc8 536 Gene3D G3DSA:3.40.309.10 289 485 2.0E-62 T 28-03-2018 CU254_RS10185 c23d23c764c561e2de833bba8c82bfc8 536 SUPERFAMILY SSF53720 39 504 1.31E-137 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CU254_RS10185 c23d23c764c561e2de833bba8c82bfc8 536 Gene3D G3DSA:3.40.605.10 28 288 1.4E-75 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CU254_RS10185 c23d23c764c561e2de833bba8c82bfc8 536 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 272 279 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CU254_RS10185 c23d23c764c561e2de833bba8c82bfc8 536 Pfam PF00171 Aldehyde dehydrogenase family 45 499 1.2E-139 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CU254_RS21650 b4fbcd50ef7bb8e0607d077887bd3b72 203 Gene3D G3DSA:3.40.109.10 5 202 6.6E-33 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CU254_RS21650 b4fbcd50ef7bb8e0607d077887bd3b72 203 Pfam PF00881 Nitroreductase family 22 181 9.5E-17 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CU254_RS21650 b4fbcd50ef7bb8e0607d077887bd3b72 203 SUPERFAMILY SSF55469 20 201 1.18E-42 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CU254_RS22890 2b71c2e1de5dbf7ed48533225acb3c9f 309 Pfam PF00005 ABC transporter 71 231 7.3E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS22890 2b71c2e1de5dbf7ed48533225acb3c9f 309 SMART SM00382 80 280 4.9E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS22890 2b71c2e1de5dbf7ed48533225acb3c9f 309 SUPERFAMILY SSF52540 54 302 5.92E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS22890 2b71c2e1de5dbf7ed48533225acb3c9f 309 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 280 302 4.7E-11 T 28-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CU254_RS22890 2b71c2e1de5dbf7ed48533225acb3c9f 309 Gene3D G3DSA:3.40.50.300 49 303 1.2E-59 T 28-03-2018 CU254_RS36880 ba40391f3f6917135eb9547cfcd438c9 140 SUPERFAMILY SSF82784 1 138 6.41E-40 T 28-03-2018 IPR003718 OsmC/Ohr family CU254_RS36880 ba40391f3f6917135eb9547cfcd438c9 140 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 5 137 4.3E-51 T 28-03-2018 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 CU254_RS36880 ba40391f3f6917135eb9547cfcd438c9 140 Gene3D G3DSA:2.20.25.10 2 46 3.0E-17 T 28-03-2018 CU254_RS36880 ba40391f3f6917135eb9547cfcd438c9 140 Gene3D G3DSA:3.30.300.20 47 140 4.5E-25 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CU254_RS36880 ba40391f3f6917135eb9547cfcd438c9 140 Pfam PF02566 OsmC-like protein 42 136 3.1E-18 T 28-03-2018 IPR003718 OsmC/Ohr family CU254_RS16620 62e382fab74bc4395e3bd8e1603e429e 561 SUPERFAMILY SSF54373 268 362 3.34E-7 T 28-03-2018 CU254_RS16620 62e382fab74bc4395e3bd8e1603e429e 561 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 417 532 3.3E-28 T 28-03-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CU254_RS16620 62e382fab74bc4395e3bd8e1603e429e 561 Gene3D G3DSA:3.50.50.60 23 430 2.4E-62 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS16620 62e382fab74bc4395e3bd8e1603e429e 561 SUPERFAMILY SSF51905 37 266 9.93E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS16620 62e382fab74bc4395e3bd8e1603e429e 561 SUPERFAMILY SSF51905 305 317 9.93E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS16620 62e382fab74bc4395e3bd8e1603e429e 561 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 51 61 1.8E-29 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CU254_RS16620 62e382fab74bc4395e3bd8e1603e429e 561 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 112 124 1.8E-29 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CU254_RS16620 62e382fab74bc4395e3bd8e1603e429e 561 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 385 397 1.8E-29 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CU254_RS16620 62e382fab74bc4395e3bd8e1603e429e 561 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 38 50 1.8E-29 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CU254_RS16620 62e382fab74bc4395e3bd8e1603e429e 561 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 356 362 1.8E-29 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CU254_RS16620 62e382fab74bc4395e3bd8e1603e429e 561 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 67 79 1.8E-29 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CU254_RS16620 62e382fab74bc4395e3bd8e1603e429e 561 Pfam PF01266 FAD dependent oxidoreductase 39 405 9.5E-55 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CU254_RS39650 d5670b6d7a3a5d7fe298bffbbf11539a 374 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 29 316 4.7E-32 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CU254_RS39650 d5670b6d7a3a5d7fe298bffbbf11539a 374 Gene3D G3DSA:3.40.50.300 6 335 2.8E-27 T 28-03-2018 CU254_RS39650 d5670b6d7a3a5d7fe298bffbbf11539a 374 SUPERFAMILY SSF52540 8 354 1.62E-26 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS39650 d5670b6d7a3a5d7fe298bffbbf11539a 374 PIRSF PIRSF029347 120 351 9.3E-29 T 28-03-2018 IPR014555 RecF-like CU254_RS39650 d5670b6d7a3a5d7fe298bffbbf11539a 374 PIRSF PIRSF029347 6 126 6.2E-15 T 28-03-2018 IPR014555 RecF-like CU254_RS09995 65e06efe2f0715998759a8e85d3189b2 160 Gene3D G3DSA:2.60.120.10 85 138 4.2E-4 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS27200 370276c981ce6e9008e5cbee6fae3c98 503 SMART SM00331 272 498 1.1E-35 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CU254_RS27200 370276c981ce6e9008e5cbee6fae3c98 503 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 307 497 2.8E-40 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CU254_RS27200 370276c981ce6e9008e5cbee6fae3c98 503 Gene3D G3DSA:3.60.40.10 254 499 2.0E-35 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CU254_RS27200 370276c981ce6e9008e5cbee6fae3c98 503 SUPERFAMILY SSF81606 294 496 1.83E-8 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CU254_RS27200 370276c981ce6e9008e5cbee6fae3c98 503 SUPERFAMILY SSF55781 118 261 8.5E-5 T 28-03-2018 IPR029016 GAF domain-like CU254_RS27200 370276c981ce6e9008e5cbee6fae3c98 503 Gene3D G3DSA:3.30.450.40 91 253 2.9E-10 T 28-03-2018 IPR029016 GAF domain-like CU254_RS07265 d1e6b68d174c2f6068ec8c20b01da981 327 Pfam PF02470 MlaD protein 38 111 1.1E-13 T 28-03-2018 IPR003399 Mce/MlaD CU254_RS07265 d1e6b68d174c2f6068ec8c20b01da981 327 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 89 105 2.0E-10 T 28-03-2018 IPR005693 Virulence factor Mce protein CU254_RS07265 d1e6b68d174c2f6068ec8c20b01da981 327 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 127 151 2.0E-10 T 28-03-2018 IPR005693 Virulence factor Mce protein CU254_RS07265 d1e6b68d174c2f6068ec8c20b01da981 327 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 296 315 2.0E-10 T 28-03-2018 IPR005693 Virulence factor Mce protein CU254_RS07265 d1e6b68d174c2f6068ec8c20b01da981 327 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 176 194 2.0E-10 T 28-03-2018 IPR005693 Virulence factor Mce protein CU254_RS07265 d1e6b68d174c2f6068ec8c20b01da981 327 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 12 290 1.6E-62 T 28-03-2018 IPR005693 Virulence factor Mce protein CU254_RS07265 d1e6b68d174c2f6068ec8c20b01da981 327 Gene3D G3DSA:1.20.1170.10 132 303 5.4E-6 T 28-03-2018 CU254_RS07020 0fab407c7955086efba7553813fe1bd2 474 Pfam PF00330 Aconitase family (aconitate hydratase) 13 464 1.9E-159 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CU254_RS07020 0fab407c7955086efba7553813fe1bd2 474 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 7 473 60.565 T 28-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 CU254_RS07020 0fab407c7955086efba7553813fe1bd2 474 PRINTS PR00415 Aconitase family signature 202 215 1.7E-47 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CU254_RS07020 0fab407c7955086efba7553813fe1bd2 474 PRINTS PR00415 Aconitase family signature 216 229 1.7E-47 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CU254_RS07020 0fab407c7955086efba7553813fe1bd2 474 PRINTS PR00415 Aconitase family signature 115 123 1.7E-47 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CU254_RS07020 0fab407c7955086efba7553813fe1bd2 474 PRINTS PR00415 Aconitase family signature 140 155 1.7E-47 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CU254_RS07020 0fab407c7955086efba7553813fe1bd2 474 PRINTS PR00415 Aconitase family signature 89 102 1.7E-47 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CU254_RS07020 0fab407c7955086efba7553813fe1bd2 474 PRINTS PR00415 Aconitase family signature 126 139 1.7E-47 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CU254_RS07020 0fab407c7955086efba7553813fe1bd2 474 PRINTS PR00415 Aconitase family signature 293 307 1.7E-47 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CU254_RS07020 0fab407c7955086efba7553813fe1bd2 474 PRINTS PR00415 Aconitase family signature 406 419 1.7E-47 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CU254_RS07020 0fab407c7955086efba7553813fe1bd2 474 PRINTS PR00415 Aconitase family signature 350 361 1.7E-47 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CU254_RS07020 0fab407c7955086efba7553813fe1bd2 474 Gene3D G3DSA:3.40.1060.10 161 295 2.5E-45 T 28-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CU254_RS07020 0fab407c7955086efba7553813fe1bd2 474 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 8 466 4.3E-230 T 28-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 CU254_RS07020 0fab407c7955086efba7553813fe1bd2 474 ProSitePatterns PS00450 Aconitase family signature 1. 346 362 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CU254_RS07020 0fab407c7955086efba7553813fe1bd2 474 ProSitePatterns PS01244 Aconitase family signature 2. 406 419 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CU254_RS07020 0fab407c7955086efba7553813fe1bd2 474 Gene3D G3DSA:3.30.499.10 331 474 5.8E-52 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CU254_RS07020 0fab407c7955086efba7553813fe1bd2 474 SUPERFAMILY SSF53732 8 472 1.57E-164 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CU254_RS07020 0fab407c7955086efba7553813fe1bd2 474 Gene3D G3DSA:3.30.499.10 1 160 2.0E-42 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CU254_RS31865 4db3e0cf6c4b5f1a2b5708131aaa2726 170 Pfam PF03703 Bacterial PH domain 80 156 1.5E-15 T 28-03-2018 IPR005182 Domain of unknown function DUF304 CU254_RS17360 23c1733edceca0b08cc11e12282b47f2 430 Gene3D G3DSA:3.30.200.20 93 230 2.8E-22 T 28-03-2018 CU254_RS17360 23c1733edceca0b08cc11e12282b47f2 430 SMART SM00220 115 391 0.0039 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CU254_RS17360 23c1733edceca0b08cc11e12282b47f2 430 Pfam PF03109 ABC1 family 104 221 4.8E-29 T 28-03-2018 IPR004147 UbiB domain CU254_RS17360 23c1733edceca0b08cc11e12282b47f2 430 Gene3D G3DSA:1.10.510.10 231 376 1.0E-6 T 28-03-2018 CU254_RS17360 23c1733edceca0b08cc11e12282b47f2 430 SUPERFAMILY SSF56112 86 162 5.13E-28 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS17360 23c1733edceca0b08cc11e12282b47f2 430 SUPERFAMILY SSF56112 195 313 5.13E-28 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS05585 9bb9a3be86ce6483b5de354327d2942c 115 Gene3D G3DSA:1.10.10.60 26 52 4.1E-7 T 28-03-2018 CU254_RS05585 9bb9a3be86ce6483b5de354327d2942c 115 Gene3D G3DSA:3.30.1190.10 53 91 2.2E-7 T 28-03-2018 CU254_RS05585 9bb9a3be86ce6483b5de354327d2942c 115 SUPERFAMILY SSF47413 21 87 2.14E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS05585 9bb9a3be86ce6483b5de354327d2942c 115 Pfam PF13560 Helix-turn-helix domain 27 80 2.8E-12 T 28-03-2018 CU254_RS05585 9bb9a3be86ce6483b5de354327d2942c 115 SMART SM00530 30 85 5.9E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS00155 9da4b4a105b20a0351d53a9bc780d4e6 790 SUPERFAMILY SSF55874 518 642 4.98E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS00155 9da4b4a105b20a0351d53a9bc780d4e6 790 SMART SM00387 533 645 3.6E-5 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS00155 9da4b4a105b20a0351d53a9bc780d4e6 790 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 538 642 4.2E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS00155 9da4b4a105b20a0351d53a9bc780d4e6 790 Gene3D G3DSA:3.30.565.10 449 644 1.2E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS00155 9da4b4a105b20a0351d53a9bc780d4e6 790 Pfam PF08376 Nitrate and nitrite sensing 69 308 2.1E-31 T 28-03-2018 IPR013587 Nitrate/nitrite sensing protein CU254_RS16305 67a9bae0dc4385b868c805f92b51c1de 297 SUPERFAMILY SSF46785 1 111 4.23E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS16305 67a9bae0dc4385b868c805f92b51c1de 297 Gene3D G3DSA:3.40.190.10 173 262 1.4E-21 T 28-03-2018 CU254_RS16305 67a9bae0dc4385b868c805f92b51c1de 297 Pfam PF03466 LysR substrate binding domain 88 286 1.2E-27 T 28-03-2018 IPR005119 LysR, substrate-binding CU254_RS16305 67a9bae0dc4385b868c805f92b51c1de 297 Gene3D G3DSA:1.10.10.10 1 84 5.3E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS16305 67a9bae0dc4385b868c805f92b51c1de 297 SUPERFAMILY SSF53850 91 287 3.08E-30 T 28-03-2018 CU254_RS16305 67a9bae0dc4385b868c805f92b51c1de 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 5.7E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS16305 67a9bae0dc4385b868c805f92b51c1de 297 Gene3D G3DSA:3.40.190.10 89 172 1.7E-13 T 28-03-2018 CU254_RS22290 43f5a319a26f334f14083cd71f698934 334 Gene3D G3DSA:1.10.10.580 243 309 5.3E-11 T 28-03-2018 CU254_RS22290 43f5a319a26f334f14083cd71f698934 334 Pfam PF02616 Segregation and condensation protein ScpA 89 309 7.7E-57 T 28-03-2018 IPR003768 Segregation and condensation protein A CU254_RS37645 6cc5d7a8ab390dd05b77b1f285bab11b 220 SUPERFAMILY SSF55469 2 84 3.4E-42 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CU254_RS37645 6cc5d7a8ab390dd05b77b1f285bab11b 220 SUPERFAMILY SSF55469 123 218 3.4E-42 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CU254_RS37645 6cc5d7a8ab390dd05b77b1f285bab11b 220 Gene3D G3DSA:3.40.109.10 1 220 1.3E-45 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CU254_RS37645 6cc5d7a8ab390dd05b77b1f285bab11b 220 Pfam PF00881 Nitroreductase family 7 197 1.8E-26 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CU254_RS08990 53a91b2049c4c32028178d12f6fa8d21 211 SUPERFAMILY SSF46785 127 197 8.7E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS08990 53a91b2049c4c32028178d12f6fa8d21 211 Gene3D G3DSA:3.90.79.10 1 127 1.3E-27 T 28-03-2018 CU254_RS08990 53a91b2049c4c32028178d12f6fa8d21 211 Gene3D G3DSA:1.10.10.10 128 203 9.6E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS08990 53a91b2049c4c32028178d12f6fa8d21 211 SUPERFAMILY SSF55811 3 123 1.1E-27 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CU254_RS08990 53a91b2049c4c32028178d12f6fa8d21 211 Pfam PF00293 NUDIX domain 6 106 7.2E-11 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CU254_RS12815 4287736015905a29b871b46dc2fa54a3 633 ProSitePatterns PS00211 ABC transporters family signature. 465 479 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS12815 4287736015905a29b871b46dc2fa54a3 633 Pfam PF00005 ABC transporter 334 492 1.0E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS12815 4287736015905a29b871b46dc2fa54a3 633 SMART SM00382 343 549 1.9E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS12815 4287736015905a29b871b46dc2fa54a3 633 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 544 608 9.2E-14 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CU254_RS12815 4287736015905a29b871b46dc2fa54a3 633 SUPERFAMILY SSF52540 318 564 3.41E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS12815 4287736015905a29b871b46dc2fa54a3 633 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 101 276 4.0E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS12815 4287736015905a29b871b46dc2fa54a3 633 Gene3D G3DSA:1.10.3720.10 14 272 2.9E-32 T 28-03-2018 CU254_RS12815 4287736015905a29b871b46dc2fa54a3 633 SUPERFAMILY SSF161098 78 266 3.66E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS12815 4287736015905a29b871b46dc2fa54a3 633 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 542 627 1.9E-19 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CU254_RS12815 4287736015905a29b871b46dc2fa54a3 633 Gene3D G3DSA:3.40.50.300 315 631 4.9E-72 T 28-03-2018 CU254_RS40390 eb2d400b423ba4e02f038147b9c38b64 332 Gene3D G3DSA:1.10.540.10 1 111 1.5E-15 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS40390 eb2d400b423ba4e02f038147b9c38b64 332 Gene3D G3DSA:1.20.140.10 220 328 7.1E-4 T 28-03-2018 CU254_RS40390 eb2d400b423ba4e02f038147b9c38b64 332 SUPERFAMILY SSF56645 3 203 4.06E-27 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS40390 eb2d400b423ba4e02f038147b9c38b64 332 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 4 104 1.1E-9 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS40390 eb2d400b423ba4e02f038147b9c38b64 332 Gene3D G3DSA:2.40.110.10 117 204 0.0022 T 28-03-2018 CU254_RS17605 2bc45f1640944fdcb7e08f675d358c68 371 PIRSF PIRSF000183 1 371 7.2E-160 T 28-03-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 CU254_RS17605 2bc45f1640944fdcb7e08f675d358c68 371 SMART SM01003 4 137 8.6E-78 T 28-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CU254_RS17605 2bc45f1640944fdcb7e08f675d358c68 371 Gene3D G3DSA:3.40.50.720 1 191 1.8E-46 T 28-03-2018 CU254_RS17605 2bc45f1640944fdcb7e08f675d358c68 371 Gene3D G3DSA:3.40.50.720 192 371 7.3E-42 T 28-03-2018 CU254_RS17605 2bc45f1640944fdcb7e08f675d358c68 371 SMART SM01002 149 297 1.3E-76 T 28-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CU254_RS17605 2bc45f1640944fdcb7e08f675d358c68 371 SUPERFAMILY SSF51735 137 303 2.75E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS17605 2bc45f1640944fdcb7e08f675d358c68 371 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 137 2.5E-45 T 28-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CU254_RS17605 2bc45f1640944fdcb7e08f675d358c68 371 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 370 2.4E-161 T 28-03-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 CU254_RS17605 2bc45f1640944fdcb7e08f675d358c68 371 SUPERFAMILY SSF52283 305 360 6.29E-66 T 28-03-2018 CU254_RS17605 2bc45f1640944fdcb7e08f675d358c68 371 SUPERFAMILY SSF52283 1 137 6.29E-66 T 28-03-2018 CU254_RS17605 2bc45f1640944fdcb7e08f675d358c68 371 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 141 352 1.6E-76 T 28-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CU254_RS38445 da35c96d218a22adad057abb0adad82f 263 SMART SM00421 177 234 2.1E-22 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS38445 da35c96d218a22adad057abb0adad82f 263 SUPERFAMILY SSF52172 21 147 2.72E-11 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS38445 da35c96d218a22adad057abb0adad82f 263 Gene3D G3DSA:1.10.10.10 147 244 4.2E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS38445 da35c96d218a22adad057abb0adad82f 263 SUPERFAMILY SSF46894 171 240 5.1E-20 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS38445 da35c96d218a22adad057abb0adad82f 263 Pfam PF00196 Bacterial regulatory proteins, luxR family 179 234 4.0E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS38445 da35c96d218a22adad057abb0adad82f 263 Gene3D G3DSA:3.40.50.2300 21 146 8.2E-14 T 28-03-2018 CU254_RS38445 da35c96d218a22adad057abb0adad82f 263 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 194 210 2.6E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS38445 da35c96d218a22adad057abb0adad82f 263 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 210 222 2.6E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS38445 da35c96d218a22adad057abb0adad82f 263 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 194 2.6E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS38445 da35c96d218a22adad057abb0adad82f 263 ProSitePatterns PS00622 LuxR-type HTH domain signature. 194 221 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS38445 da35c96d218a22adad057abb0adad82f 263 Pfam PF00072 Response regulator receiver domain 24 135 9.8E-6 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS11625 e9ae59ef1762fc1695d09c58c2f20317 285 Pfam PF03668 P-loop ATPase protein family 1 285 9.9E-111 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 CU254_RS11625 e9ae59ef1762fc1695d09c58c2f20317 285 Gene3D G3DSA:3.40.50.300 2 160 4.3E-12 T 28-03-2018 CU254_RS11625 e9ae59ef1762fc1695d09c58c2f20317 285 SUPERFAMILY SSF52540 3 154 1.2E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS11625 e9ae59ef1762fc1695d09c58c2f20317 285 PIRSF PIRSF005052 1 285 4.4E-113 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 CU254_RS11625 e9ae59ef1762fc1695d09c58c2f20317 285 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 1 284 41.373 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 CU254_RS32695 ff9a102654cf13dac370b7ce4ce4e488 335 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS32695 ff9a102654cf13dac370b7ce4ce4e488 335 Gene3D G3DSA:3.40.50.300 25 314 2.1E-54 T 28-03-2018 CU254_RS32695 ff9a102654cf13dac370b7ce4ce4e488 335 SMART SM00382 49 232 8.4E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS32695 ff9a102654cf13dac370b7ce4ce4e488 335 Pfam PF00005 ABC transporter 41 185 2.1E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS32695 ff9a102654cf13dac370b7ce4ce4e488 335 SUPERFAMILY SSF52540 22 249 8.62E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS19440 b473036e56859568275f0f0d5d4b2b69 295 Pfam PF04655 Aminoglycoside/hydroxyurea antibiotic resistance kinase 51 235 4.2E-16 T 28-03-2018 IPR006748 Aminoglycoside/hydroxyurea antibiotic resistance kinase GO:0006468|GO:0016773|GO:0019748 CU254_RS19440 b473036e56859568275f0f0d5d4b2b69 295 Gene3D G3DSA:3.90.1200.10 57 242 9.3E-12 T 28-03-2018 CU254_RS19440 b473036e56859568275f0f0d5d4b2b69 295 SUPERFAMILY SSF56112 33 234 1.4E-22 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS35790 50a0b94b08dc79d87323d79690f2826b 252 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 9 131 1.3E-11 T 28-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CU254_RS35790 50a0b94b08dc79d87323d79690f2826b 252 Gene3D G3DSA:3.30.1050.10 128 241 3.6E-5 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CU254_RS35790 50a0b94b08dc79d87323d79690f2826b 252 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 11 227 8.4E-19 T 28-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CU254_RS35790 50a0b94b08dc79d87323d79690f2826b 252 SUPERFAMILY SSF55718 172 230 1.26E-5 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CU254_RS35790 50a0b94b08dc79d87323d79690f2826b 252 SUPERFAMILY SSF109854 4 136 6.71E-10 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CU254_RS35790 50a0b94b08dc79d87323d79690f2826b 252 Gene3D G3DSA:1.20.120.450 2 127 5.0E-13 T 28-03-2018 CU254_RS20725 3ef2bd94c6ca5ce1756f9306a814df26 422 SUPERFAMILY SSF48264 29 416 2.1E-97 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS20725 3ef2bd94c6ca5ce1756f9306a814df26 422 PRINTS PR00359 B-class P450 signature 152 168 3.2E-58 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS20725 3ef2bd94c6ca5ce1756f9306a814df26 422 PRINTS PR00359 B-class P450 signature 290 301 3.2E-58 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS20725 3ef2bd94c6ca5ce1756f9306a814df26 422 PRINTS PR00359 B-class P450 signature 367 378 3.2E-58 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS20725 3ef2bd94c6ca5ce1756f9306a814df26 422 PRINTS PR00359 B-class P450 signature 105 116 3.2E-58 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS20725 3ef2bd94c6ca5ce1756f9306a814df26 422 PRINTS PR00359 B-class P450 signature 169 184 3.2E-58 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS20725 3ef2bd94c6ca5ce1756f9306a814df26 422 PRINTS PR00359 B-class P450 signature 309 336 3.2E-58 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS20725 3ef2bd94c6ca5ce1756f9306a814df26 422 PRINTS PR00359 B-class P450 signature 209 231 3.2E-58 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS20725 3ef2bd94c6ca5ce1756f9306a814df26 422 PRINTS PR00359 B-class P450 signature 358 367 3.2E-58 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS20725 3ef2bd94c6ca5ce1756f9306a814df26 422 PRINTS PR00359 B-class P450 signature 337 352 3.2E-58 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS20725 3ef2bd94c6ca5ce1756f9306a814df26 422 Gene3D G3DSA:1.10.630.10 32 415 9.6E-79 T 28-03-2018 CU254_RS20725 3ef2bd94c6ca5ce1756f9306a814df26 422 PRINTS PR00385 P450 superfamily signature 367 378 1.1E-7 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS20725 3ef2bd94c6ca5ce1756f9306a814df26 422 PRINTS PR00385 P450 superfamily signature 290 301 1.1E-7 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS20725 3ef2bd94c6ca5ce1756f9306a814df26 422 PRINTS PR00385 P450 superfamily signature 255 272 1.1E-7 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS20725 3ef2bd94c6ca5ce1756f9306a814df26 422 PRINTS PR00385 P450 superfamily signature 358 367 1.1E-7 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS20725 3ef2bd94c6ca5ce1756f9306a814df26 422 Pfam PF00067 Cytochrome P450 203 283 2.3E-6 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS20725 3ef2bd94c6ca5ce1756f9306a814df26 422 Pfam PF00067 Cytochrome P450 288 388 6.6E-18 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS20725 3ef2bd94c6ca5ce1756f9306a814df26 422 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 360 369 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CU254_RS23245 338eab0160986c4a5d22668dbb0dfee2 337 SUPERFAMILY SSF50494 167 323 1.76E-16 T 28-03-2018 IPR009003 Peptidase S1, PA clan CU254_RS23245 338eab0160986c4a5d22668dbb0dfee2 337 Gene3D G3DSA:3.30.300.50 11 87 1.4E-12 T 28-03-2018 IPR035070 Streptogrisin prodomain CU254_RS23245 338eab0160986c4a5d22668dbb0dfee2 337 PIRSF PIRSF001134 1 337 2.6E-65 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CU254_RS23245 338eab0160986c4a5d22668dbb0dfee2 337 Gene3D G3DSA:2.40.10.10 163 238 8.1E-14 T 28-03-2018 CU254_RS23245 338eab0160986c4a5d22668dbb0dfee2 337 Gene3D G3DSA:2.40.10.10 239 323 5.5E-7 T 28-03-2018 CU254_RS23245 338eab0160986c4a5d22668dbb0dfee2 337 Gene3D G3DSA:3.30.300.50 88 157 1.5E-13 T 28-03-2018 IPR035070 Streptogrisin prodomain CU254_RS23245 338eab0160986c4a5d22668dbb0dfee2 337 Pfam PF02983 Alpha-lytic protease prodomain 91 146 2.1E-10 T 28-03-2018 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 CU254_RS23245 338eab0160986c4a5d22668dbb0dfee2 337 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 243 263 2.8E-22 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CU254_RS23245 338eab0160986c4a5d22668dbb0dfee2 337 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 283 306 2.8E-22 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CU254_RS23245 338eab0160986c4a5d22668dbb0dfee2 337 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 189 203 2.8E-22 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CU254_RS23245 338eab0160986c4a5d22668dbb0dfee2 337 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 264 281 2.8E-22 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CU254_RS23245 338eab0160986c4a5d22668dbb0dfee2 337 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 307 321 2.8E-22 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CU254_RS06440 4cb8a418e05242675cf299008048dbeb 1083 SUPERFAMILY SSF48208 324 733 6.97E-19 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CU254_RS06440 4cb8a418e05242675cf299008048dbeb 1083 Gene3D G3DSA:3.30.2080.10 638 783 6.3E-48 T 28-03-2018 CU254_RS06440 4cb8a418e05242675cf299008048dbeb 1083 Gene3D G3DSA:2.60.40.10 788 892 4.8E-5 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS06440 4cb8a418e05242675cf299008048dbeb 1083 Gene3D G3DSA:1.20.1050.60 409 501 8.4E-21 T 28-03-2018 CU254_RS06440 4cb8a418e05242675cf299008048dbeb 1083 Gene3D G3DSA:2.70.98.10 42 385 6.9E-102 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 CU254_RS06440 4cb8a418e05242675cf299008048dbeb 1083 Gene3D G3DSA:1.20.1610.10 503 637 2.6E-45 T 28-03-2018 CU254_RS06440 4cb8a418e05242675cf299008048dbeb 1083 TIGRFAM TIGR01180 aman2_put: putative alpha-1,2-mannosidase 35 769 1.7E-154 T 28-03-2018 IPR005887 Alpha-1,2-mannosidase, putative CU254_RS06440 4cb8a418e05242675cf299008048dbeb 1083 Pfam PF07971 Glycosyl hydrolase family 92 299 768 2.5E-158 T 28-03-2018 IPR012939 Glycosyl hydrolase family 92 CU254_RS05255 26a13c62bf0733523d2951c455a19491 512 SUPERFAMILY SSF56112 13 310 2.56E-70 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS05255 26a13c62bf0733523d2951c455a19491 512 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 145 157 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CU254_RS05255 26a13c62bf0733523d2951c455a19491 512 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 28 51 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 CU254_RS05255 26a13c62bf0733523d2951c455a19491 512 Pfam PF00069 Protein kinase domain 22 276 3.8E-45 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CU254_RS05255 26a13c62bf0733523d2951c455a19491 512 SMART SM00220 22 281 6.8E-60 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CU254_RS05255 26a13c62bf0733523d2951c455a19491 512 Gene3D G3DSA:1.10.510.10 109 296 1.1E-45 T 28-03-2018 CU254_RS05255 26a13c62bf0733523d2951c455a19491 512 Gene3D G3DSA:3.30.200.20 10 108 8.8E-23 T 28-03-2018 CU254_RS03700 cc5e5fbc87dc2061f6d8634a311ec868 105 SUPERFAMILY SSF46785 3 103 3.13E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS03700 cc5e5fbc87dc2061f6d8634a311ec868 105 Pfam PF03551 Transcriptional regulator PadR-like family 14 86 5.2E-22 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CU254_RS03700 cc5e5fbc87dc2061f6d8634a311ec868 105 Gene3D G3DSA:1.10.10.10 1 105 2.4E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS03560 6087008305cbfa44c4a7c0ccefb06dc2 297 SUPERFAMILY SSF48150 99 276 4.54E-25 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CU254_RS03560 6087008305cbfa44c4a7c0ccefb06dc2 297 Gene3D G3DSA:1.10.340.30 86 260 7.2E-19 T 28-03-2018 CU254_RS42245 db76ba220d645bc8e45f7101692c0e63 294 Pfam PF04055 Radical SAM superfamily 2 135 3.9E-13 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CU254_RS42245 db76ba220d645bc8e45f7101692c0e63 294 Pfam PF13353 4Fe-4S single cluster domain 5 72 7.9E-5 T 28-03-2018 CU254_RS42245 db76ba220d645bc8e45f7101692c0e63 294 Gene3D G3DSA:3.20.20.70 165 260 0.0046 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS42245 db76ba220d645bc8e45f7101692c0e63 294 Gene3D G3DSA:3.20.20.70 1 164 1.8E-21 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS42245 db76ba220d645bc8e45f7101692c0e63 294 Pfam PF13186 Iron-sulfur cluster-binding domain 187 240 6.9E-6 T 28-03-2018 IPR023885 4Fe4S-binding SPASM domain CU254_RS42245 db76ba220d645bc8e45f7101692c0e63 294 SUPERFAMILY SSF102114 1 235 1.44E-33 T 28-03-2018 CU254_RS09180 e0f4b205eabb36ce5779504e0f1e6925 199 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 161 173 - T 28-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CU254_RS09180 e0f4b205eabb36ce5779504e0f1e6925 199 Gene3D G3DSA:3.30.230.40 1 89 3.3E-33 T 28-03-2018 CU254_RS09180 e0f4b205eabb36ce5779504e0f1e6925 199 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 62 75 - T 28-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CU254_RS09180 e0f4b205eabb36ce5779504e0f1e6925 199 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 32 179 5.4E-59 T 28-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CU254_RS09180 e0f4b205eabb36ce5779504e0f1e6925 199 SUPERFAMILY SSF54211 3 86 8.35E-32 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CU254_RS09180 e0f4b205eabb36ce5779504e0f1e6925 199 SUPERFAMILY SSF54211 88 184 6.32E-28 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CU254_RS09180 e0f4b205eabb36ce5779504e0f1e6925 199 Gene3D G3DSA:3.30.230.40 91 199 6.0E-33 T 28-03-2018 CU254_RS09180 e0f4b205eabb36ce5779504e0f1e6925 199 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 3 199 41.041 T 28-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CU254_RS15185 1cbd115339579780754bd69c7787b534 141 Pfam PF13577 SnoaL-like domain 5 125 4.9E-18 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CU254_RS15185 1cbd115339579780754bd69c7787b534 141 SUPERFAMILY SSF54427 5 130 4.13E-28 T 28-03-2018 IPR032710 NTF2-like domain CU254_RS15185 1cbd115339579780754bd69c7787b534 141 Gene3D G3DSA:3.10.450.50 4 134 2.3E-26 T 28-03-2018 CU254_RS38865 9b59096a62de0d27301cdbd235a60d57 161 Pfam PF01047 MarR family 31 89 2.5E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS38865 9b59096a62de0d27301cdbd235a60d57 161 Gene3D G3DSA:1.10.287.100 108 139 1.1E-6 T 28-03-2018 CU254_RS38865 9b59096a62de0d27301cdbd235a60d57 161 SMART SM00347 24 124 1.6E-15 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS38865 9b59096a62de0d27301cdbd235a60d57 161 SUPERFAMILY SSF46785 10 141 3.79E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS38865 9b59096a62de0d27301cdbd235a60d57 161 Gene3D G3DSA:1.10.10.10 5 107 8.1E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS34330 99471e52bae4d4aed114cb533829a54b 448 PRINTS PR01036 Tetracycline resistance protein TetB signature 220 238 4.5E-10 T 28-03-2018 CU254_RS34330 99471e52bae4d4aed114cb533829a54b 448 PRINTS PR01036 Tetracycline resistance protein TetB signature 10 34 4.5E-10 T 28-03-2018 CU254_RS34330 99471e52bae4d4aed114cb533829a54b 448 PRINTS PR01036 Tetracycline resistance protein TetB signature 101 121 4.5E-10 T 28-03-2018 CU254_RS34330 99471e52bae4d4aed114cb533829a54b 448 PRINTS PR01036 Tetracycline resistance protein TetB signature 131 155 4.5E-10 T 28-03-2018 CU254_RS34330 99471e52bae4d4aed114cb533829a54b 448 SUPERFAMILY SSF103473 3 190 1.57E-63 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS34330 99471e52bae4d4aed114cb533829a54b 448 SUPERFAMILY SSF103473 235 430 1.57E-63 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS34330 99471e52bae4d4aed114cb533829a54b 448 Gene3D G3DSA:1.20.1250.20 2 192 1.7E-28 T 28-03-2018 CU254_RS34330 99471e52bae4d4aed114cb533829a54b 448 Pfam PF07690 Major Facilitator Superfamily 11 394 6.8E-46 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS34330 99471e52bae4d4aed114cb533829a54b 448 Gene3D G3DSA:1.20.1250.20 239 446 4.3E-24 T 28-03-2018 CU254_RS18570 fef4506cfc3b954ad56a72dea63506e3 589 SUPERFAMILY SSF81340 22 453 2.22E-116 T 28-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 CU254_RS18570 fef4506cfc3b954ad56a72dea63506e3 589 Gene3D G3DSA:1.10.3080.10 22 456 4.8E-109 T 28-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 CU254_RS18570 fef4506cfc3b954ad56a72dea63506e3 589 PRINTS PR00762 Chloride channel signature 105 122 4.9E-25 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CU254_RS18570 fef4506cfc3b954ad56a72dea63506e3 589 PRINTS PR00762 Chloride channel signature 185 204 4.9E-25 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CU254_RS18570 fef4506cfc3b954ad56a72dea63506e3 589 PRINTS PR00762 Chloride channel signature 384 400 4.9E-25 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CU254_RS18570 fef4506cfc3b954ad56a72dea63506e3 589 PRINTS PR00762 Chloride channel signature 402 421 4.9E-25 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CU254_RS18570 fef4506cfc3b954ad56a72dea63506e3 589 PRINTS PR00762 Chloride channel signature 349 369 4.9E-25 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CU254_RS18570 fef4506cfc3b954ad56a72dea63506e3 589 SUPERFAMILY SSF54631 464 582 8.95E-13 T 28-03-2018 CU254_RS18570 fef4506cfc3b954ad56a72dea63506e3 589 Gene3D G3DSA:3.10.580.10 457 587 1.5E-13 T 28-03-2018 CU254_RS18570 fef4506cfc3b954ad56a72dea63506e3 589 Pfam PF00654 Voltage gated chloride channel 92 434 6.8E-101 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CU254_RS05370 47da4b5748cd5cddf024a38645cdb12e 529 TIGRFAM TIGR02777 LigD_PE_dom: DNA ligase D, 3'-phosphoesterase domain 8 163 4.1E-64 T 28-03-2018 IPR014144 DNA ligase D, 3'-phosphoesterase domain CU254_RS05370 47da4b5748cd5cddf024a38645cdb12e 529 Pfam PF13298 DNA polymerase Ligase (LigD) 39 145 7.9E-37 T 28-03-2018 IPR014144 DNA ligase D, 3'-phosphoesterase domain CU254_RS03290 4764075710fd8fa1d4b637356d5341c6 292 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 22 139 1.7E-14 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CU254_RS03290 4764075710fd8fa1d4b637356d5341c6 292 SUPERFAMILY SSF55961 165 266 3.06E-10 T 28-03-2018 CU254_RS03290 4764075710fd8fa1d4b637356d5341c6 292 Gene3D G3DSA:3.30.530.20 4 153 1.7E-28 T 28-03-2018 IPR023393 START-like domain CU254_RS03290 4764075710fd8fa1d4b637356d5341c6 292 SUPERFAMILY SSF55961 7 159 8.06E-33 T 28-03-2018 CU254_RS03290 4764075710fd8fa1d4b637356d5341c6 292 Gene3D G3DSA:3.30.530.20 154 284 2.1E-8 T 28-03-2018 IPR023393 START-like domain CU254_RS06000 698015be6a58d4a9f0f5dda1a250a7e2 315 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 95 108 - T 28-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 CU254_RS06000 698015be6a58d4a9f0f5dda1a250a7e2 315 Gene3D G3DSA:3.40.190.10 188 311 2.3E-13 T 28-03-2018 CU254_RS06000 698015be6a58d4a9f0f5dda1a250a7e2 315 SUPERFAMILY SSF53850 61 300 3.78E-53 T 28-03-2018 CU254_RS06000 698015be6a58d4a9f0f5dda1a250a7e2 315 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 72 300 3.2E-58 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CU254_RS06000 698015be6a58d4a9f0f5dda1a250a7e2 315 SMART SM00062 71 303 1.0E-42 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CU254_RS06000 698015be6a58d4a9f0f5dda1a250a7e2 315 Gene3D G3DSA:3.40.190.10 66 187 1.6E-30 T 28-03-2018 CU254_RS35540 e7e070172d5832ef4868f3738ceea354 222 Pfam PF00106 short chain dehydrogenase 3 181 2.3E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS35540 e7e070172d5832ef4868f3738ceea354 222 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 163 3.5E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS35540 e7e070172d5832ef4868f3738ceea354 222 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 66 77 3.5E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS35540 e7e070172d5832ef4868f3738ceea354 222 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 19 3.5E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS35540 e7e070172d5832ef4868f3738ceea354 222 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 182 3.5E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS35540 e7e070172d5832ef4868f3738ceea354 222 SUPERFAMILY SSF51735 3 222 4.92E-51 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS35540 e7e070172d5832ef4868f3738ceea354 222 Gene3D G3DSA:3.40.50.720 2 222 2.1E-35 T 28-03-2018 CU254_RS33685 d1e5b05b0521e1a42f5d6fd9518d3ef1 258 Pfam PF13560 Helix-turn-helix domain 5 66 2.6E-10 T 28-03-2018 CU254_RS33685 d1e5b05b0521e1a42f5d6fd9518d3ef1 258 SMART SM00530 8 63 1.4E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS33685 d1e5b05b0521e1a42f5d6fd9518d3ef1 258 SUPERFAMILY SSF47413 4 62 3.66E-12 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS33685 d1e5b05b0521e1a42f5d6fd9518d3ef1 258 Gene3D G3DSA:1.10.260.40 2 189 4.9E-13 T 28-03-2018 CU254_RS06735 a28b0ca302eebbd45e81c7cb62010cdc 301 SUPERFAMILY SSF50129 1 131 6.24E-35 T 28-03-2018 IPR011032 GroES-like CU254_RS06735 a28b0ca302eebbd45e81c7cb62010cdc 301 Pfam PF00107 Zinc-binding dehydrogenase 149 235 2.9E-11 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CU254_RS06735 a28b0ca302eebbd45e81c7cb62010cdc 301 Gene3D G3DSA:3.90.180.10 1 139 3.1E-41 T 28-03-2018 CU254_RS06735 a28b0ca302eebbd45e81c7cb62010cdc 301 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 87 4.7E-7 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CU254_RS06735 a28b0ca302eebbd45e81c7cb62010cdc 301 Gene3D G3DSA:3.40.50.720 140 252 2.8E-15 T 28-03-2018 CU254_RS06735 a28b0ca302eebbd45e81c7cb62010cdc 301 SMART SM00829 10 298 5.5E-11 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CU254_RS06735 a28b0ca302eebbd45e81c7cb62010cdc 301 SUPERFAMILY SSF51735 111 240 5.84E-27 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS00340 380c893bb602ae6f3a2e15bb123c985b 279 Pfam PF00106 short chain dehydrogenase 13 193 1.9E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS00340 380c893bb602ae6f3a2e15bb123c985b 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 1.0E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS00340 380c893bb602ae6f3a2e15bb123c985b 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 1.0E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS00340 380c893bb602ae6f3a2e15bb123c985b 279 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 1.0E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS00340 380c893bb602ae6f3a2e15bb123c985b 279 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS00340 380c893bb602ae6f3a2e15bb123c985b 279 SUPERFAMILY SSF51735 6 251 8.0E-60 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS00340 380c893bb602ae6f3a2e15bb123c985b 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 1.1E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS00340 380c893bb602ae6f3a2e15bb123c985b 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.1E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS00340 380c893bb602ae6f3a2e15bb123c985b 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.1E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS00340 380c893bb602ae6f3a2e15bb123c985b 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.1E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS00340 380c893bb602ae6f3a2e15bb123c985b 279 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.1E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS00340 380c893bb602ae6f3a2e15bb123c985b 279 Gene3D G3DSA:3.40.50.720 2 259 2.6E-52 T 28-03-2018 CU254_RS05005 6326df0e829567140aa32c9d6f9cb7dc 276 Gene3D G3DSA:3.40.190.10 32 142 1.0E-22 T 28-03-2018 CU254_RS05005 6326df0e829567140aa32c9d6f9cb7dc 276 Gene3D G3DSA:3.40.190.10 143 225 4.4E-22 T 28-03-2018 CU254_RS05005 6326df0e829567140aa32c9d6f9cb7dc 276 SMART SM00062 39 263 1.4E-58 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CU254_RS05005 6326df0e829567140aa32c9d6f9cb7dc 276 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 40 255 2.4E-47 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CU254_RS05005 6326df0e829567140aa32c9d6f9cb7dc 276 SUPERFAMILY SSF53850 3 257 6.88E-52 T 28-03-2018 CU254_RS32270 d28d8b4183e30f6bdf69fb7c7ce43de6 230 SUPERFAMILY SSF161098 19 206 1.09E-26 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS32270 d28d8b4183e30f6bdf69fb7c7ce43de6 230 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 39 210 1.9E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS32270 d28d8b4183e30f6bdf69fb7c7ce43de6 230 Gene3D G3DSA:1.10.3720.10 2 220 1.7E-26 T 28-03-2018 CU254_RS40830 9f01162ce824639b32064d7ea099cedc 413 Pfam PF05977 Transmembrane secretion effector 5 402 1.2E-37 T 28-03-2018 IPR010290 Transmembrane secretion effector CU254_RS40830 9f01162ce824639b32064d7ea099cedc 413 SUPERFAMILY SSF103473 10 398 9.42E-43 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS40830 9f01162ce824639b32064d7ea099cedc 413 Gene3D G3DSA:1.20.1250.20 1 203 3.8E-16 T 28-03-2018 CU254_RS40830 9f01162ce824639b32064d7ea099cedc 413 Gene3D G3DSA:1.20.1250.20 204 399 1.7E-18 T 28-03-2018 CU254_RS19420 6969ac4724708f3ec4770db0c0c78da3 469 ProSitePatterns PS01270 Band 7 protein family signature. 133 161 - T 28-03-2018 IPR018080 Band 7/stomatin-like, conserved site CU254_RS19420 6969ac4724708f3ec4770db0c0c78da3 469 Pfam PF01145 SPFH domain / Band 7 family 23 193 1.8E-32 T 28-03-2018 IPR001107 Band 7 domain CU254_RS19420 6969ac4724708f3ec4770db0c0c78da3 469 SMART SM00244 19 177 2.6E-57 T 28-03-2018 IPR001107 Band 7 domain CU254_RS19420 6969ac4724708f3ec4770db0c0c78da3 469 SUPERFAMILY SSF117892 50 184 1.22E-39 T 28-03-2018 IPR001107 Band 7 domain CU254_RS19420 6969ac4724708f3ec4770db0c0c78da3 469 PRINTS PR00721 Stomatin signature 74 95 1.8E-34 T 28-03-2018 IPR001972 Stomatin family GO:0016020 CU254_RS19420 6969ac4724708f3ec4770db0c0c78da3 469 PRINTS PR00721 Stomatin signature 109 126 1.8E-34 T 28-03-2018 IPR001972 Stomatin family GO:0016020 CU254_RS19420 6969ac4724708f3ec4770db0c0c78da3 469 PRINTS PR00721 Stomatin signature 153 171 1.8E-34 T 28-03-2018 IPR001972 Stomatin family GO:0016020 CU254_RS19420 6969ac4724708f3ec4770db0c0c78da3 469 PRINTS PR00721 Stomatin signature 129 152 1.8E-34 T 28-03-2018 IPR001972 Stomatin family GO:0016020 CU254_RS19420 6969ac4724708f3ec4770db0c0c78da3 469 PRINTS PR00721 Stomatin signature 26 48 1.8E-34 T 28-03-2018 IPR001972 Stomatin family GO:0016020 CU254_RS19420 6969ac4724708f3ec4770db0c0c78da3 469 PRINTS PR00721 Stomatin signature 172 193 1.8E-34 T 28-03-2018 IPR001972 Stomatin family GO:0016020 CU254_RS08265 5501d7f13285ceeacd365d2f4b070fac 457 Gene3D G3DSA:1.10.45.10 411 450 3.1E-16 T 28-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CU254_RS08265 5501d7f13285ceeacd365d2f4b070fac 457 Gene3D G3DSA:3.30.43.10 1 90 1.3E-23 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CU254_RS08265 5501d7f13285ceeacd365d2f4b070fac 457 SUPERFAMILY SSF55103 217 454 1.31E-56 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CU254_RS08265 5501d7f13285ceeacd365d2f4b070fac 457 Pfam PF02913 FAD linked oxidases, C-terminal domain 220 450 1.7E-58 T 28-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CU254_RS08265 5501d7f13285ceeacd365d2f4b070fac 457 SUPERFAMILY SSF56176 2 211 1.12E-71 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CU254_RS08265 5501d7f13285ceeacd365d2f4b070fac 457 Pfam PF01565 FAD binding domain 38 177 5.1E-44 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CU254_RS08265 5501d7f13285ceeacd365d2f4b070fac 457 Gene3D G3DSA:3.30.465.10 91 236 1.1E-41 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CU254_RS16145 325db491bc8326443ff078ceb386f8cb 1455 ProSitePatterns PS00455 Putative AMP-binding domain signature. 613 624 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS16145 325db491bc8326443ff078ceb386f8cb 1455 Gene3D G3DSA:3.40.50.980 616 775 4.6E-35 T 28-03-2018 CU254_RS16145 325db491bc8326443ff078ceb386f8cb 1455 Pfam PF00501 AMP-binding enzyme 484 878 1.6E-86 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS16145 325db491bc8326443ff078ceb386f8cb 1455 Gene3D G3DSA:3.40.50.980 476 615 1.6E-36 T 28-03-2018 CU254_RS16145 325db491bc8326443ff078ceb386f8cb 1455 Gene3D G3DSA:3.30.559.10 21 216 4.8E-41 T 28-03-2018 CU254_RS16145 325db491bc8326443ff078ceb386f8cb 1455 SUPERFAMILY SSF56801 443 989 4.58E-136 T 28-03-2018 CU254_RS16145 325db491bc8326443ff078ceb386f8cb 1455 Pfam PF07993 Male sterility protein 1089 1325 1.1E-55 T 28-03-2018 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 CU254_RS16145 325db491bc8326443ff078ceb386f8cb 1455 SUPERFAMILY SSF52777 208 451 9.78E-63 T 28-03-2018 CU254_RS16145 325db491bc8326443ff078ceb386f8cb 1455 Pfam PF00550 Phosphopantetheine attachment site 977 1041 8.0E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS16145 325db491bc8326443ff078ceb386f8cb 1455 TIGRFAM TIGR01746 Thioester-redct: thioester reductase domain 1088 1441 8.3E-81 T 28-03-2018 IPR010080 Thioester reductase-like domain CU254_RS16145 325db491bc8326443ff078ceb386f8cb 1455 Gene3D G3DSA:3.40.50.720 1084 1415 4.3E-34 T 28-03-2018 CU254_RS16145 325db491bc8326443ff078ceb386f8cb 1455 Gene3D G3DSA:1.10.1200.10 982 1047 6.3E-22 T 28-03-2018 CU254_RS16145 325db491bc8326443ff078ceb386f8cb 1455 SUPERFAMILY SSF51735 1085 1377 2.62E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS16145 325db491bc8326443ff078ceb386f8cb 1455 Gene3D G3DSA:2.30.38.10 786 868 7.2E-25 T 28-03-2018 CU254_RS16145 325db491bc8326443ff078ceb386f8cb 1455 Pfam PF13193 AMP-binding enzyme C-terminal domain 886 952 2.1E-7 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS16145 325db491bc8326443ff078ceb386f8cb 1455 SUPERFAMILY SSF52777 32 222 5.89E-45 T 28-03-2018 CU254_RS16145 325db491bc8326443ff078ceb386f8cb 1455 PIRSF PIRSF001617 919 1454 7.3E-65 T 28-03-2018 CU254_RS16145 325db491bc8326443ff078ceb386f8cb 1455 PIRSF PIRSF001617 210 592 7.8E-19 T 28-03-2018 CU254_RS16145 325db491bc8326443ff078ceb386f8cb 1455 PIRSF PIRSF001617 840 922 2.7E-12 T 28-03-2018 CU254_RS16145 325db491bc8326443ff078ceb386f8cb 1455 PIRSF PIRSF001617 584 846 0.004 T 28-03-2018 CU254_RS16145 325db491bc8326443ff078ceb386f8cb 1455 Gene3D G3DSA:3.30.300.30 873 981 2.4E-32 T 28-03-2018 CU254_RS16145 325db491bc8326443ff078ceb386f8cb 1455 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 503 902 2.1E-115 T 28-03-2018 IPR010071 Amino acid adenylation domain CU254_RS16145 325db491bc8326443ff078ceb386f8cb 1455 SUPERFAMILY SSF47336 969 1041 2.62E-18 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS16145 325db491bc8326443ff078ceb386f8cb 1455 Pfam PF00668 Condensation domain 35 458 6.8E-90 T 28-03-2018 IPR001242 Condensation domain CU254_RS12395 9701b544ef5ebf5d5b78824158d0075b 111 Gene3D G3DSA:2.102.10.10 2 111 1.2E-25 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CU254_RS12395 9701b544ef5ebf5d5b78824158d0075b 111 Pfam PF00355 Rieske [2Fe-2S] domain 4 89 9.3E-17 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CU254_RS12395 9701b544ef5ebf5d5b78824158d0075b 111 SUPERFAMILY SSF50022 1 106 4.58E-27 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CU254_RS21475 2047222b777756b63112037a6d5833b8 362 SUPERFAMILY SSF52540 35 266 3.6E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS21475 2047222b777756b63112037a6d5833b8 362 Gene3D G3DSA:1.10.8.60 199 269 1.4E-31 T 28-03-2018 CU254_RS21475 2047222b777756b63112037a6d5833b8 362 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 268 342 3.0E-22 T 28-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 CU254_RS21475 2047222b777756b63112037a6d5833b8 362 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 39 341 1.4E-136 T 28-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 CU254_RS21475 2047222b777756b63112037a6d5833b8 362 Gene3D G3DSA:3.40.50.300 33 196 1.6E-24 T 28-03-2018 CU254_RS21475 2047222b777756b63112037a6d5833b8 362 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 268 341 8.0E-30 T 28-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 CU254_RS21475 2047222b777756b63112037a6d5833b8 362 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 362 157.504 T 28-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 CU254_RS21475 2047222b777756b63112037a6d5833b8 362 SUPERFAMILY SSF46785 271 345 2.72E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS21475 2047222b777756b63112037a6d5833b8 362 SMART SM00382 66 209 9.3E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS21475 2047222b777756b63112037a6d5833b8 362 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 21 250 9.4E-108 T 28-03-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 CU254_RS21475 2047222b777756b63112037a6d5833b8 362 Gene3D G3DSA:1.10.10.10 272 342 9.9E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS30370 071581bbd015355ff753f4022979d467 398 Gene3D G3DSA:3.40.640.10 28 263 6.2E-45 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS30370 071581bbd015355ff753f4022979d467 398 Pfam PF00266 Aminotransferase class-V 22 391 2.6E-56 T 28-03-2018 IPR000192 Aminotransferase class V domain CU254_RS30370 071581bbd015355ff753f4022979d467 398 Gene3D G3DSA:3.90.1150.10 264 398 4.8E-28 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS30370 071581bbd015355ff753f4022979d467 398 TIGRFAM TIGR01976 am_tr_V_VC1184: cysteine desulfurase family protein 3 395 3.7E-146 T 28-03-2018 IPR011340 Cysteine desulfurase-related CU254_RS30370 071581bbd015355ff753f4022979d467 398 SUPERFAMILY SSF53383 3 397 7.11E-82 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS18455 1d3897400e1e8964129fb71d8866c840 325 Gene3D G3DSA:3.40.50.1820 6 325 1.7E-55 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS18455 1d3897400e1e8964129fb71d8866c840 325 Pfam PF07859 alpha/beta hydrolase fold 90 295 2.3E-53 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CU254_RS18455 1d3897400e1e8964129fb71d8866c840 325 SUPERFAMILY SSF53474 25 321 7.14E-63 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS14040 88e69f56e0247a01b96a86eb30d61bcd 324 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 77 138 3.4E-13 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CU254_RS14040 88e69f56e0247a01b96a86eb30d61bcd 324 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 297 1.1E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS14040 88e69f56e0247a01b96a86eb30d61bcd 324 SUPERFAMILY SSF161098 77 282 2.62E-35 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS14040 88e69f56e0247a01b96a86eb30d61bcd 324 Gene3D G3DSA:1.10.3720.10 40 302 1.5E-37 T 28-03-2018 CU254_RS20535 a34a787803bc24bcfa6d09f44477fb9b 225 Gene3D G3DSA:1.10.260.40 66 94 1.4E-8 T 28-03-2018 CU254_RS20535 a34a787803bc24bcfa6d09f44477fb9b 225 SUPERFAMILY SSF46689 35 111 9.98E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS20535 a34a787803bc24bcfa6d09f44477fb9b 225 Gene3D G3DSA:1.10.10.60 5 65 1.3E-10 T 28-03-2018 CU254_RS20535 a34a787803bc24bcfa6d09f44477fb9b 225 Pfam PF00440 Bacterial regulatory proteins, tetR family 44 88 1.2E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS20535 a34a787803bc24bcfa6d09f44477fb9b 225 Gene3D G3DSA:1.10.357.10 95 222 1.5E-11 T 28-03-2018 CU254_RS20535 a34a787803bc24bcfa6d09f44477fb9b 225 SUPERFAMILY SSF48498 121 219 2.86E-13 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS01125 0da8e439565905f667086b9d0c03e778 501 Gene3D G3DSA:3.30.300.30 405 501 1.3E-26 T 28-03-2018 CU254_RS01125 0da8e439565905f667086b9d0c03e778 501 Gene3D G3DSA:3.40.50.980 8 156 5.5E-36 T 28-03-2018 CU254_RS01125 0da8e439565905f667086b9d0c03e778 501 Pfam PF00501 AMP-binding enzyme 17 410 6.4E-90 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS01125 0da8e439565905f667086b9d0c03e778 501 Pfam PF13193 AMP-binding enzyme C-terminal domain 419 494 1.9E-17 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS01125 0da8e439565905f667086b9d0c03e778 501 Gene3D G3DSA:2.30.38.10 308 403 1.4E-19 T 28-03-2018 CU254_RS01125 0da8e439565905f667086b9d0c03e778 501 SUPERFAMILY SSF56801 12 501 1.96E-134 T 28-03-2018 CU254_RS01125 0da8e439565905f667086b9d0c03e778 501 ProSitePatterns PS00455 Putative AMP-binding domain signature. 151 162 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS01125 0da8e439565905f667086b9d0c03e778 501 Gene3D G3DSA:3.40.50.980 157 307 8.6E-47 T 28-03-2018 CU254_RS13350 c5347e213fa39c0c220db29da88dc605 135 Gene3D G3DSA:3.30.565.10 11 135 3.5E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS13350 c5347e213fa39c0c220db29da88dc605 135 Pfam PF13581 Histidine kinase-like ATPase domain 16 133 5.2E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS13350 c5347e213fa39c0c220db29da88dc605 135 SUPERFAMILY SSF55874 43 131 1.66E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS35980 48ef0eb5c2c69e51f4cdbae38d038778 157 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 4 156 30.108 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CU254_RS35980 48ef0eb5c2c69e51f4cdbae38d038778 157 SUPERFAMILY SSF69765 4 156 1.44E-48 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CU254_RS35980 48ef0eb5c2c69e51f4cdbae38d038778 157 Gene3D G3DSA:3.30.1330.50 1 157 3.4E-57 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CU254_RS35980 48ef0eb5c2c69e51f4cdbae38d038778 157 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 5 156 1.6E-44 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CU254_RS35980 48ef0eb5c2c69e51f4cdbae38d038778 157 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 38 53 - T 28-03-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CU254_RS35980 48ef0eb5c2c69e51f4cdbae38d038778 157 Pfam PF02542 YgbB family 5 154 8.5E-46 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CU254_RS19805 620d4ba617c7d29510634e7a6c6c4f1e 185 Pfam PF11706 CGNR zinc finger 142 180 2.2E-11 T 28-03-2018 IPR021005 Zinc finger, CGNR CU254_RS19805 620d4ba617c7d29510634e7a6c6c4f1e 185 SUPERFAMILY SSF160904 5 180 8.89E-34 T 28-03-2018 CU254_RS19805 620d4ba617c7d29510634e7a6c6c4f1e 185 Pfam PF07336 Putative stress-induced transcription regulator 8 137 1.3E-12 T 28-03-2018 IPR010852 Putative stress-induced transcription regulator CU254_RS19805 620d4ba617c7d29510634e7a6c6c4f1e 185 Gene3D G3DSA:1.10.3300.10 1 183 5.1E-37 T 28-03-2018 IPR023286 ABATE domain CU254_RS24970 ca4e3176bdc8e74da31621128911a165 172 Gene3D G3DSA:3.30.300.70 1 82 3.4E-23 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal CU254_RS24970 ca4e3176bdc8e74da31621128911a165 172 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 7 149 19.841 T 28-03-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 CU254_RS24970 ca4e3176bdc8e74da31621128911a165 172 Pfam PF02576 RimP N-terminal domain 12 85 1.2E-19 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal CU254_RS24970 ca4e3176bdc8e74da31621128911a165 172 SUPERFAMILY SSF75420 5 85 4.45E-19 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal CU254_RS00590 82608d9cec03593b9a2995ea4474dc02 182 Pfam PF03061 Thioesterase superfamily 64 133 1.5E-9 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CU254_RS00590 82608d9cec03593b9a2995ea4474dc02 182 Gene3D G3DSA:3.10.129.10 5 155 3.5E-27 T 28-03-2018 CU254_RS00590 82608d9cec03593b9a2995ea4474dc02 182 SUPERFAMILY SSF54637 9 148 7.19E-32 T 28-03-2018 IPR029069 HotDog domain CU254_RS39790 984dcc2fc335c10fb97be73f6d16c1b8 211 Gene3D G3DSA:1.10.10.10 2 100 2.5E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS39790 984dcc2fc335c10fb97be73f6d16c1b8 211 Pfam PF03551 Transcriptional regulator PadR-like family 14 89 6.3E-11 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CU254_RS39790 984dcc2fc335c10fb97be73f6d16c1b8 211 SUPERFAMILY SSF46785 10 181 3.03E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS18525 25d64461daa4698a08d604293a78b4ca 212 Gene3D G3DSA:1.10.357.10 68 190 4.0E-10 T 28-03-2018 CU254_RS18525 25d64461daa4698a08d604293a78b4ca 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 60 1.3E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS18525 25d64461daa4698a08d604293a78b4ca 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 2.0E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS18525 25d64461daa4698a08d604293a78b4ca 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 2.0E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS18525 25d64461daa4698a08d604293a78b4ca 212 SUPERFAMILY SSF46689 3 76 1.05E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS18525 25d64461daa4698a08d604293a78b4ca 212 Gene3D G3DSA:1.10.260.40 37 67 1.2E-11 T 28-03-2018 CU254_RS18525 25d64461daa4698a08d604293a78b4ca 212 Gene3D G3DSA:1.10.10.60 2 36 6.5E-13 T 28-03-2018 CU254_RS17610 bc491ed2c0866eec1a2cef65775c9607 329 SUPERFAMILY SSF53659 12 319 1.11E-73 T 28-03-2018 CU254_RS17610 bc491ed2c0866eec1a2cef65775c9607 329 Gene3D G3DSA:3.40.50.10750 137 292 8.2E-59 T 28-03-2018 CU254_RS17610 bc491ed2c0866eec1a2cef65775c9607 329 Pfam PF01515 Phosphate acetyl/butaryl transferase 11 316 3.7E-94 T 28-03-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0008152|GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CU254_RS17610 bc491ed2c0866eec1a2cef65775c9607 329 PIRSF PIRSF000428 1 322 2.0E-90 T 28-03-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 CU254_RS17250 3ef75ae0b8984acd1de3e55a45a83a4e 146 SUPERFAMILY SSF46785 6 136 1.5E-33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS17250 3ef75ae0b8984acd1de3e55a45a83a4e 146 Pfam PF01638 HxlR-like helix-turn-helix 16 103 1.2E-25 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type CU254_RS17250 3ef75ae0b8984acd1de3e55a45a83a4e 146 Gene3D G3DSA:1.10.10.10 3 141 1.5E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS06740 dce6972199bd32268e39a08f18e8e892 454 Gene3D G3DSA:1.20.1250.20 252 454 1.1E-17 T 28-03-2018 CU254_RS06740 dce6972199bd32268e39a08f18e8e892 454 SUPERFAMILY SSF103473 247 452 5.36E-49 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS06740 dce6972199bd32268e39a08f18e8e892 454 SUPERFAMILY SSF103473 9 203 5.36E-49 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS06740 dce6972199bd32268e39a08f18e8e892 454 Pfam PF07690 Major Facilitator Superfamily 276 445 6.1E-9 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS06740 dce6972199bd32268e39a08f18e8e892 454 Pfam PF07690 Major Facilitator Superfamily 26 244 5.3E-24 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS06740 dce6972199bd32268e39a08f18e8e892 454 Gene3D G3DSA:1.20.1250.20 16 201 1.0E-29 T 28-03-2018 CU254_RS07935 7f9bf6f1a89ef85c929d0e02ffe501d8 150 Gene3D G3DSA:1.10.287.100 118 149 3.8E-10 T 28-03-2018 CU254_RS07935 7f9bf6f1a89ef85c929d0e02ffe501d8 150 Pfam PF01047 MarR family 46 96 4.2E-13 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS07935 7f9bf6f1a89ef85c929d0e02ffe501d8 150 SUPERFAMILY SSF46785 24 149 1.31E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS07935 7f9bf6f1a89ef85c929d0e02ffe501d8 150 ProSitePatterns PS01117 MarR-type HTH domain signature. 72 106 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CU254_RS07935 7f9bf6f1a89ef85c929d0e02ffe501d8 150 SMART SM00347 34 134 8.2E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS07935 7f9bf6f1a89ef85c929d0e02ffe501d8 150 Gene3D G3DSA:1.10.10.10 8 117 1.1E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS28720 1cd8ebb790a2b93ef8f13f2a902f7776 481 Pfam PF02875 Mur ligase family, glutamate ligase domain 327 410 1.0E-12 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CU254_RS28720 1cd8ebb790a2b93ef8f13f2a902f7776 481 Gene3D G3DSA:3.40.50.720 23 109 1.1E-15 T 28-03-2018 CU254_RS28720 1cd8ebb790a2b93ef8f13f2a902f7776 481 Gene3D G3DSA:3.90.190.20 328 474 1.9E-26 T 28-03-2018 CU254_RS28720 1cd8ebb790a2b93ef8f13f2a902f7776 481 Gene3D G3DSA:3.40.1190.10 110 327 1.0E-39 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CU254_RS28720 1cd8ebb790a2b93ef8f13f2a902f7776 481 SUPERFAMILY SSF53244 326 470 6.11E-29 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CU254_RS28720 1cd8ebb790a2b93ef8f13f2a902f7776 481 Pfam PF08245 Mur ligase middle domain 126 306 6.4E-23 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CU254_RS28720 1cd8ebb790a2b93ef8f13f2a902f7776 481 Pfam PF01225 Mur ligase family, catalytic domain 24 120 9.4E-18 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CU254_RS28720 1cd8ebb790a2b93ef8f13f2a902f7776 481 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 24 468 9.9E-106 T 28-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CU254_RS28720 1cd8ebb790a2b93ef8f13f2a902f7776 481 SUPERFAMILY SSF53623 107 324 6.3E-47 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CU254_RS28720 1cd8ebb790a2b93ef8f13f2a902f7776 481 SUPERFAMILY SSF51984 23 108 4.05E-21 T 28-03-2018 CU254_RS27985 095ccb83928915473b28bcec96186e3c 195 SUPERFAMILY SSF46689 10 85 1.7E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS27985 095ccb83928915473b28bcec96186e3c 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 2.0E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS27985 095ccb83928915473b28bcec96186e3c 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 2.0E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS27985 095ccb83928915473b28bcec96186e3c 195 ProSitePatterns PS01081 TetR-type HTH domain signature. 33 64 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CU254_RS27985 095ccb83928915473b28bcec96186e3c 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 64 5.4E-19 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS27985 095ccb83928915473b28bcec96186e3c 195 Gene3D G3DSA:1.10.357.10 62 195 6.4E-23 T 28-03-2018 CU254_RS27985 095ccb83928915473b28bcec96186e3c 195 Gene3D G3DSA:1.10.10.60 11 61 4.9E-19 T 28-03-2018 CU254_RS34395 1c281a1360da5587152aab3c6330424e 198 Gene3D G3DSA:1.10.10.60 1 59 2.7E-16 T 28-03-2018 CU254_RS34395 1c281a1360da5587152aab3c6330424e 198 SUPERFAMILY SSF46689 4 77 1.85E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS34395 1c281a1360da5587152aab3c6330424e 198 Gene3D G3DSA:1.10.357.10 60 195 5.0E-20 T 28-03-2018 CU254_RS34395 1c281a1360da5587152aab3c6330424e 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 57 1.2E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS31715 71714b5ba16afabb9fd4042e87ea36a0 393 SUPERFAMILY SSF55874 288 384 2.51E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS31715 71714b5ba16afabb9fd4042e87ea36a0 393 Gene3D G3DSA:3.30.565.10 260 392 2.4E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS31715 71714b5ba16afabb9fd4042e87ea36a0 393 Pfam PF07730 Histidine kinase 187 251 3.0E-17 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CU254_RS26815 6c21ed7e71b22d975da178ab8a2df7fe 411 Pfam PF01494 FAD binding domain 306 347 7.0E-8 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CU254_RS26815 6c21ed7e71b22d975da178ab8a2df7fe 411 Pfam PF01494 FAD binding domain 2 167 1.7E-8 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CU254_RS26815 6c21ed7e71b22d975da178ab8a2df7fe 411 Gene3D G3DSA:3.50.50.60 1 374 2.9E-36 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS26815 6c21ed7e71b22d975da178ab8a2df7fe 411 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 311 326 4.1E-21 T 28-03-2018 CU254_RS26815 6c21ed7e71b22d975da178ab8a2df7fe 411 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 149 164 4.1E-21 T 28-03-2018 CU254_RS26815 6c21ed7e71b22d975da178ab8a2df7fe 411 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 326 342 4.1E-21 T 28-03-2018 CU254_RS26815 6c21ed7e71b22d975da178ab8a2df7fe 411 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 4.1E-21 T 28-03-2018 CU254_RS26815 6c21ed7e71b22d975da178ab8a2df7fe 411 SUPERFAMILY SSF51905 298 407 3.78E-49 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS26815 6c21ed7e71b22d975da178ab8a2df7fe 411 SUPERFAMILY SSF51905 2 170 3.78E-49 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS26995 d5a217cb41183bd560ba3094fd285a6b 450 SUPERFAMILY SSF103473 15 433 1.11E-44 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS26995 d5a217cb41183bd560ba3094fd285a6b 450 Gene3D G3DSA:1.20.1250.20 16 219 1.5E-18 T 28-03-2018 CU254_RS26995 d5a217cb41183bd560ba3094fd285a6b 450 Gene3D G3DSA:1.20.1250.20 230 435 4.6E-20 T 28-03-2018 CU254_RS26995 d5a217cb41183bd560ba3094fd285a6b 450 Pfam PF07690 Major Facilitator Superfamily 34 388 8.8E-31 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS07340 81cbaa2171d31723b7220a536fbc2187 231 SMART SM00535 12 148 7.5E-48 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CU254_RS07340 81cbaa2171d31723b7220a536fbc2187 231 Hamap MF_00104 Ribonuclease 3 [rnc]. 1 217 29.25 T 28-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 CU254_RS07340 81cbaa2171d31723b7220a536fbc2187 231 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 10 219 2.9E-67 T 28-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 CU254_RS07340 81cbaa2171d31723b7220a536fbc2187 231 SUPERFAMILY SSF69065 5 156 3.31E-43 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CU254_RS07340 81cbaa2171d31723b7220a536fbc2187 231 SMART SM00358 155 221 1.6E-23 T 28-03-2018 IPR014720 Double-stranded RNA-binding domain CU254_RS07340 81cbaa2171d31723b7220a536fbc2187 231 ProSitePatterns PS00517 Ribonuclease III family signature. 34 42 - T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CU254_RS07340 81cbaa2171d31723b7220a536fbc2187 231 SUPERFAMILY SSF54768 109 220 9.11E-25 T 28-03-2018 CU254_RS07340 81cbaa2171d31723b7220a536fbc2187 231 Pfam PF14622 Ribonuclease-III-like 10 137 4.0E-33 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CU254_RS07340 81cbaa2171d31723b7220a536fbc2187 231 Gene3D G3DSA:3.30.160.20 153 228 2.8E-21 T 28-03-2018 CU254_RS07340 81cbaa2171d31723b7220a536fbc2187 231 Pfam PF00035 Double-stranded RNA binding motif 155 220 4.3E-14 T 28-03-2018 IPR014720 Double-stranded RNA-binding domain CU254_RS07340 81cbaa2171d31723b7220a536fbc2187 231 Gene3D G3DSA:1.10.1520.10 7 148 1.7E-37 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CU254_RS10635 177e82ab6a7639c04bfef28197a6f488 228 Gene3D G3DSA:3.40.50.1000 59 228 2.8E-30 T 28-03-2018 IPR023214 HAD-like domain CU254_RS10635 177e82ab6a7639c04bfef28197a6f488 228 SUPERFAMILY SSF56784 4 224 1.85E-40 T 28-03-2018 IPR023214 HAD-like domain CU254_RS10635 177e82ab6a7639c04bfef28197a6f488 228 Pfam PF00702 haloacid dehalogenase-like hydrolase 5 186 7.8E-15 T 28-03-2018 CU254_RS10635 177e82ab6a7639c04bfef28197a6f488 228 TIGRFAM TIGR03351 PhnX-like: phosphonatase-like hydrolase 5 222 1.2E-71 T 28-03-2018 IPR022468 Phosphonatase-like hydrolase CU254_RS08400 379bbf0c4d773d52e929e297190e4fb9 286 SUPERFAMILY SSF55166 130 282 3.85E-25 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CU254_RS08400 379bbf0c4d773d52e929e297190e4fb9 286 Pfam PF13539 D-alanyl-D-alanine carboxypeptidase 204 281 2.6E-19 T 28-03-2018 CU254_RS08400 379bbf0c4d773d52e929e297190e4fb9 286 Gene3D G3DSA:3.30.1380.10 134 282 2.1E-19 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CU254_RS13080 ce9cc924c73706517620b4509111691f 955 SUPERFAMILY SSF49785 44 221 1.15E-27 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS13080 ce9cc924c73706517620b4509111691f 955 Pfam PF00703 Glycosyl hydrolases family 2 239 352 2.5E-12 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 CU254_RS13080 ce9cc924c73706517620b4509111691f 955 SUPERFAMILY SSF51445 349 702 2.23E-56 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS13080 ce9cc924c73706517620b4509111691f 955 Gene3D G3DSA:2.60.40.10 704 830 1.5E-25 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS13080 ce9cc924c73706517620b4509111691f 955 Gene3D G3DSA:2.60.40.10 836 936 3.9E-20 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS13080 ce9cc924c73706517620b4509111691f 955 SUPERFAMILY SSF49303 793 934 1.51E-24 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 CU254_RS13080 ce9cc924c73706517620b4509111691f 955 Gene3D G3DSA:3.20.20.80 361 703 2.3E-47 T 28-03-2018 CU254_RS13080 ce9cc924c73706517620b4509111691f 955 SUPERFAMILY SSF49303 704 809 6.24E-18 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 CU254_RS13080 ce9cc924c73706517620b4509111691f 955 Gene3D G3DSA:2.60.120.260 38 229 1.7E-24 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS13080 ce9cc924c73706517620b4509111691f 955 Gene3D G3DSA:2.60.40.10 230 350 9.7E-20 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS13080 ce9cc924c73706517620b4509111691f 955 SUPERFAMILY SSF49303 237 352 3.17E-18 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 CU254_RS18390 2e393f503031a9ef1ecb87c857d68306 276 Pfam PF13560 Helix-turn-helix domain 7 85 1.2E-16 T 28-03-2018 CU254_RS18390 2e393f503031a9ef1ecb87c857d68306 276 SUPERFAMILY SSF47413 29 82 8.45E-9 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS18390 2e393f503031a9ef1ecb87c857d68306 276 Gene3D G3DSA:1.10.260.40 3 101 1.4E-16 T 28-03-2018 CU254_RS18390 2e393f503031a9ef1ecb87c857d68306 276 SMART SM00530 10 82 9.7E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS18120 d3b8938b69d4ffe200b885c9b5d3578a 194 SMART SM00418 14 105 6.7E-4 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS18120 d3b8938b69d4ffe200b885c9b5d3578a 194 SUPERFAMILY SSF46785 10 83 6.66E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS18120 d3b8938b69d4ffe200b885c9b5d3578a 194 Gene3D G3DSA:1.10.10.10 7 166 8.2E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS18120 d3b8938b69d4ffe200b885c9b5d3578a 194 Pfam PF12840 Helix-turn-helix domain 14 70 5.0E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS40005 d6abfc718cdd9171238095b3ecb48d75 404 PRINTS PR01466 Bacterial arginine deiminase signature 3 23 1.4E-48 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CU254_RS40005 d6abfc718cdd9171238095b3ecb48d75 404 PRINTS PR01466 Bacterial arginine deiminase signature 336 353 1.4E-48 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CU254_RS40005 d6abfc718cdd9171238095b3ecb48d75 404 PRINTS PR01466 Bacterial arginine deiminase signature 356 370 1.4E-48 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CU254_RS40005 d6abfc718cdd9171238095b3ecb48d75 404 PRINTS PR01466 Bacterial arginine deiminase signature 379 397 1.4E-48 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CU254_RS40005 d6abfc718cdd9171238095b3ecb48d75 404 PRINTS PR01466 Bacterial arginine deiminase signature 151 169 1.4E-48 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CU254_RS40005 d6abfc718cdd9171238095b3ecb48d75 404 PRINTS PR01466 Bacterial arginine deiminase signature 179 194 1.4E-48 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CU254_RS40005 d6abfc718cdd9171238095b3ecb48d75 404 SUPERFAMILY SSF55909 2 399 1.04E-115 T 28-03-2018 CU254_RS40005 d6abfc718cdd9171238095b3ecb48d75 404 Gene3D G3DSA:3.75.10.10 6 398 6.5E-98 T 28-03-2018 CU254_RS40005 d6abfc718cdd9171238095b3ecb48d75 404 Pfam PF02274 Amidinotransferase 19 397 7.1E-97 T 28-03-2018 CU254_RS40005 d6abfc718cdd9171238095b3ecb48d75 404 Hamap MF_00242 Arginine deiminase [arcA]. 2 400 41.941 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CU254_RS40005 d6abfc718cdd9171238095b3ecb48d75 404 PIRSF PIRSF006356 1 399 5.2E-137 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CU254_RS23285 8deed896962c7a4da77dd300ab47e625 95 Gene3D G3DSA:3.30.70.100 1 95 2.9E-23 T 28-03-2018 CU254_RS23285 8deed896962c7a4da77dd300ab47e625 95 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 77 6.5E-14 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain CU254_RS23285 8deed896962c7a4da77dd300ab47e625 95 SUPERFAMILY SSF54909 1 95 1.93E-30 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS31615 a6cfe16a471ee557b3c649f21a915e7b 177 Pfam PF06271 RDD family 45 141 1.4E-5 T 28-03-2018 IPR010432 RDD CU254_RS00225 ed02dee068752f342f796de11481138c 148 TIGRFAM TIGR02246 TIGR02246: conserved hypothetical protein 7 129 6.6E-26 T 28-03-2018 IPR011944 Steroid delta5-4-isomerase KEGG: 00140+5.3.3.1|KEGG: 00984+5.3.3.1|MetaCyc: PWY-2582|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-6948|MetaCyc: PWY-699|MetaCyc: PWY-7299 CU254_RS00225 ed02dee068752f342f796de11481138c 148 SUPERFAMILY SSF54427 5 130 8.23E-34 T 28-03-2018 IPR032710 NTF2-like domain CU254_RS00225 ed02dee068752f342f796de11481138c 148 Pfam PF14534 Domain of unknown function (DUF4440) 11 120 6.5E-8 T 28-03-2018 IPR027843 Domain of unknown function DUF4440 CU254_RS00225 ed02dee068752f342f796de11481138c 148 Gene3D G3DSA:3.10.450.50 2 138 2.2E-24 T 28-03-2018 CU254_RS33715 ac4d8ca3fed69fed67229c0be5bb3c5f 238 SUPERFAMILY SSF51735 3 237 5.33E-58 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS33715 ac4d8ca3fed69fed67229c0be5bb3c5f 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 4.1E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS33715 ac4d8ca3fed69fed67229c0be5bb3c5f 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 181 4.1E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS33715 ac4d8ca3fed69fed67229c0be5bb3c5f 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 136 4.1E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS33715 ac4d8ca3fed69fed67229c0be5bb3c5f 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 219 4.1E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS33715 ac4d8ca3fed69fed67229c0be5bb3c5f 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 162 4.1E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS33715 ac4d8ca3fed69fed67229c0be5bb3c5f 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 70 81 4.1E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS33715 ac4d8ca3fed69fed67229c0be5bb3c5f 238 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 234 5.5E-44 T 28-03-2018 CU254_RS33715 ac4d8ca3fed69fed67229c0be5bb3c5f 238 Gene3D G3DSA:3.40.50.720 2 238 2.2E-53 T 28-03-2018 CU254_RS33715 ac4d8ca3fed69fed67229c0be5bb3c5f 238 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 70 81 8.8E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS33715 ac4d8ca3fed69fed67229c0be5bb3c5f 238 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 126 134 8.8E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS33715 ac4d8ca3fed69fed67229c0be5bb3c5f 238 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 162 8.8E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS37425 9c24430a8d5865dae029a086858ab468 224 Gene3D G3DSA:1.20.58.220 113 215 3.7E-16 T 28-03-2018 CU254_RS37425 9c24430a8d5865dae029a086858ab468 224 Pfam PF01895 PhoU domain 18 103 1.2E-15 T 28-03-2018 IPR026022 PhoU domain CU254_RS37425 9c24430a8d5865dae029a086858ab468 224 Pfam PF01895 PhoU domain 122 203 9.7E-10 T 28-03-2018 IPR026022 PhoU domain CU254_RS37425 9c24430a8d5865dae029a086858ab468 224 PIRSF PIRSF003107 1 215 5.3E-54 T 28-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 CU254_RS37425 9c24430a8d5865dae029a086858ab468 224 Gene3D G3DSA:1.20.58.220 1 109 1.7E-18 T 28-03-2018 CU254_RS37425 9c24430a8d5865dae029a086858ab468 224 SUPERFAMILY SSF109755 2 215 1.26E-55 T 28-03-2018 CU254_RS37425 9c24430a8d5865dae029a086858ab468 224 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 4 211 9.1E-54 T 28-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 CU254_RS31945 031739591c95715ebd75adc9a1f70464 316 Pfam PF00248 Aldo/keto reductase family 15 301 6.8E-71 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS31945 031739591c95715ebd75adc9a1f70464 316 SUPERFAMILY SSF51430 1 301 4.85E-85 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS31945 031739591c95715ebd75adc9a1f70464 316 PRINTS PR00069 Aldo-keto reductase signature 42 66 9.6E-14 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CU254_RS31945 031739591c95715ebd75adc9a1f70464 316 PRINTS PR00069 Aldo-keto reductase signature 107 125 9.6E-14 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CU254_RS31945 031739591c95715ebd75adc9a1f70464 316 PRINTS PR00069 Aldo-keto reductase signature 238 262 9.6E-14 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CU254_RS31945 031739591c95715ebd75adc9a1f70464 316 PRINTS PR00069 Aldo-keto reductase signature 138 155 9.6E-14 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CU254_RS31945 031739591c95715ebd75adc9a1f70464 316 Gene3D G3DSA:3.20.20.100 1 314 1.1E-88 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS25480 554352da12c26cc3bccd66585fd6402e 156 SUPERFAMILY SSF46785 13 130 1.08E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS25480 554352da12c26cc3bccd66585fd6402e 156 SMART SM00347 38 134 2.7E-13 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS25480 554352da12c26cc3bccd66585fd6402e 156 Pfam PF01047 MarR family 45 102 4.2E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS25480 554352da12c26cc3bccd66585fd6402e 156 Gene3D G3DSA:1.10.10.10 4 156 1.9E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS16335 29cdcdfdbb5cce3fbc71015d50612a70 295 SUPERFAMILY SSF161098 23 295 5.23E-73 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS16335 29cdcdfdbb5cce3fbc71015d50612a70 295 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 109 286 2.6E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS16335 29cdcdfdbb5cce3fbc71015d50612a70 295 Gene3D G3DSA:1.10.3720.10 17 282 6.8E-42 T 28-03-2018 CU254_RS39800 0417c6b0c79428baad843619e3230b25 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 4.6E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS39800 0417c6b0c79428baad843619e3230b25 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 4.6E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS39800 0417c6b0c79428baad843619e3230b25 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 4.6E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS39800 0417c6b0c79428baad843619e3230b25 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS39800 0417c6b0c79428baad843619e3230b25 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 5.3E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS39800 0417c6b0c79428baad843619e3230b25 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 5.3E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS39800 0417c6b0c79428baad843619e3230b25 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 5.3E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS39800 0417c6b0c79428baad843619e3230b25 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 5.3E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS39800 0417c6b0c79428baad843619e3230b25 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 5.3E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS39800 0417c6b0c79428baad843619e3230b25 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 5.3E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS39800 0417c6b0c79428baad843619e3230b25 252 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 193 5.0E-4 T 28-03-2018 CU254_RS39800 0417c6b0c79428baad843619e3230b25 252 Gene3D G3DSA:3.40.50.720 1 252 4.7E-54 T 28-03-2018 CU254_RS39800 0417c6b0c79428baad843619e3230b25 252 Pfam PF00106 short chain dehydrogenase 7 201 3.4E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS39800 0417c6b0c79428baad843619e3230b25 252 SUPERFAMILY SSF51735 7 248 1.56E-57 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS15805 b8f71248fe19d4708751ba8fdbd2ff05 310 Pfam PF00534 Glycosyl transferases group 1 197 281 6.9E-8 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CU254_RS15805 b8f71248fe19d4708751ba8fdbd2ff05 310 Gene3D G3DSA:3.40.50.2000 53 288 6.4E-14 T 28-03-2018 CU254_RS15805 b8f71248fe19d4708751ba8fdbd2ff05 310 SUPERFAMILY SSF53756 49 300 5.1E-15 T 28-03-2018 CU254_RS05390 13b808c7b52856055650e732100ece9c 177 Gene3D G3DSA:3.40.630.30 2 176 1.6E-27 T 28-03-2018 CU254_RS05390 13b808c7b52856055650e732100ece9c 177 SUPERFAMILY SSF55729 2 162 1.47E-36 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS05390 13b808c7b52856055650e732100ece9c 177 Pfam PF13302 Acetyltransferase (GNAT) domain 9 153 6.7E-27 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS37575 dc66fd995cf3d859fcc0dd4daa139258 298 Gene3D G3DSA:3.40.50.720 1 130 6.3E-31 T 28-03-2018 CU254_RS37575 dc66fd995cf3d859fcc0dd4daa139258 298 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 6 118 1.9E-19 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CU254_RS37575 dc66fd995cf3d859fcc0dd4daa139258 298 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 158 201 1.3E-4 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CU254_RS37575 dc66fd995cf3d859fcc0dd4daa139258 298 SUPERFAMILY SSF51735 4 136 2.27E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS37575 dc66fd995cf3d859fcc0dd4daa139258 298 SUPERFAMILY SSF55347 144 248 5.07E-13 T 28-03-2018 CU254_RS37575 dc66fd995cf3d859fcc0dd4daa139258 298 Gene3D G3DSA:3.30.360.10 131 298 9.2E-17 T 28-03-2018 CU254_RS20120 1bcb2e93d9cde64b2ab95cfed962bcbd 58 Gene3D G3DSA:1.10.1470.10 1 58 1.2E-16 T 28-03-2018 IPR008462 CsbD-like domain CU254_RS20120 1bcb2e93d9cde64b2ab95cfed962bcbd 58 Pfam PF05532 CsbD-like 4 54 4.5E-17 T 28-03-2018 IPR008462 CsbD-like domain CU254_RS20120 1bcb2e93d9cde64b2ab95cfed962bcbd 58 SUPERFAMILY SSF69047 3 55 1.02E-9 T 28-03-2018 IPR008462 CsbD-like domain CU254_RS22770 f328cfc5cee5080bd7d23d599d4885e2 727 Gene3D G3DSA:4.10.860.10 667 720 6.3E-13 T 28-03-2018 IPR001943 UVR domain GO:0005515 CU254_RS22770 f328cfc5cee5080bd7d23d599d4885e2 727 Pfam PF02151 UvrB/uvrC motif 684 717 2.9E-7 T 28-03-2018 IPR001943 UVR domain GO:0005515 CU254_RS22770 f328cfc5cee5080bd7d23d599d4885e2 727 SUPERFAMILY SSF52540 64 113 7.39E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS22770 f328cfc5cee5080bd7d23d599d4885e2 727 SUPERFAMILY SSF52540 489 609 7.39E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS22770 f328cfc5cee5080bd7d23d599d4885e2 727 Gene3D G3DSA:3.40.50.300 445 619 4.1E-32 T 28-03-2018 CU254_RS22770 f328cfc5cee5080bd7d23d599d4885e2 727 Pfam PF00271 Helicase conserved C-terminal domain 465 574 8.4E-18 T 28-03-2018 IPR001650 Helicase, C-terminal CU254_RS22770 f328cfc5cee5080bd7d23d599d4885e2 727 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 35 715 0.0 T 28-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 CU254_RS22770 f328cfc5cee5080bd7d23d599d4885e2 727 SUPERFAMILY SSF46600 671 719 5.62E-11 T 28-03-2018 IPR001943 UVR domain GO:0005515 CU254_RS22770 f328cfc5cee5080bd7d23d599d4885e2 727 SUPERFAMILY SSF52540 36 445 9.0E-132 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS22770 f328cfc5cee5080bd7d23d599d4885e2 727 Hamap MF_00204 UvrABC system protein B [uvrB]. 34 717 43.003 T 28-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 CU254_RS22770 f328cfc5cee5080bd7d23d599d4885e2 727 Gene3D G3DSA:3.40.50.300 42 442 2.2E-33 T 28-03-2018 CU254_RS22770 f328cfc5cee5080bd7d23d599d4885e2 727 SMART SM00490 490 576 1.7E-18 T 28-03-2018 IPR001650 Helicase, C-terminal CU254_RS22770 f328cfc5cee5080bd7d23d599d4885e2 727 Pfam PF12344 Ultra-violet resistance protein B 582 623 2.2E-20 T 28-03-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain CU254_RS22770 f328cfc5cee5080bd7d23d599d4885e2 727 Pfam PF04851 Type III restriction enzyme, res subunit 45 168 3.8E-8 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CU254_RS22770 f328cfc5cee5080bd7d23d599d4885e2 727 SMART SM00487 40 455 4.8E-27 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CU254_RS07035 54fb9c07381b37e6ddefa3638050341d 315 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 143 220 1.8E-12 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CU254_RS07035 54fb9c07381b37e6ddefa3638050341d 315 Gene3D G3DSA:3.40.50.1240 148 290 9.9E-23 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CU254_RS07035 54fb9c07381b37e6ddefa3638050341d 315 SMART SM00855 142 256 9.2E-11 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CU254_RS07035 54fb9c07381b37e6ddefa3638050341d 315 SUPERFAMILY SSF53254 141 297 1.33E-20 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CU254_RS07035 54fb9c07381b37e6ddefa3638050341d 315 PRINTS PR00502 NUDIX hydrolase family signature 47 62 4.1E-6 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CU254_RS07035 54fb9c07381b37e6ddefa3638050341d 315 PRINTS PR00502 NUDIX hydrolase family signature 33 47 4.1E-6 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CU254_RS07035 54fb9c07381b37e6ddefa3638050341d 315 SUPERFAMILY SSF55811 6 134 3.52E-29 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CU254_RS07035 54fb9c07381b37e6ddefa3638050341d 315 ProSitePatterns PS00893 Nudix box signature. 38 59 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CU254_RS07035 54fb9c07381b37e6ddefa3638050341d 315 Gene3D G3DSA:3.90.79.10 4 147 4.9E-33 T 28-03-2018 CU254_RS07035 54fb9c07381b37e6ddefa3638050341d 315 Pfam PF00293 NUDIX domain 6 132 9.1E-20 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CU254_RS40260 f6706bc52861797fd81e0ea0b61eba29 81 Pfam PF00550 Phosphopantetheine attachment site 7 66 3.3E-5 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS40260 f6706bc52861797fd81e0ea0b61eba29 81 SUPERFAMILY SSF47336 6 79 8.77E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS40260 f6706bc52861797fd81e0ea0b61eba29 81 Gene3D G3DSA:1.10.1200.10 2 81 3.9E-9 T 28-03-2018 CU254_RS15815 0347965943f2edb7a0cc87696d4099e6 296 SUPERFAMILY SSF53448 4 229 1.5E-41 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS15815 0347965943f2edb7a0cc87696d4099e6 296 Gene3D G3DSA:3.90.550.10 2 225 3.9E-37 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS15815 0347965943f2edb7a0cc87696d4099e6 296 Pfam PF00535 Glycosyl transferase family 2 5 122 1.9E-20 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CU254_RS42325 a25793ab42596e87bd3774522b225323 287 Gene3D G3DSA:2.60.40.10 172 262 2.6E-10 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS42325 a25793ab42596e87bd3774522b225323 287 SUPERFAMILY SSF49373 176 252 9.42E-7 T 28-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments CU254_RS01475 ec6c8a7c8ef1e4d6198eb70e535acc64 228 Pfam PF07335 Fungal chitosanase of glycosyl hydrolase group 75 82 212 2.0E-23 T 28-03-2018 IPR009939 Fungal chitosanase KEGG: 00520+3.2.1.132 CU254_RS29175 e0ae0ca99cd21c796d714d11d3926be4 183 SUPERFAMILY SSF143744 49 181 1.31E-30 T 28-03-2018 CU254_RS29175 e0ae0ca99cd21c796d714d11d3926be4 183 Pfam PF03928 Haem-degrading 56 178 1.3E-26 T 28-03-2018 IPR005624 Haem-degrading CU254_RS29175 e0ae0ca99cd21c796d714d11d3926be4 183 Gene3D G3DSA:3.30.450.20 10 163 4.3E-4 T 28-03-2018 CU254_RS05360 7b4113dd9d2255196268627eda845367 185 Pfam PF01381 Helix-turn-helix 13 67 5.6E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS05360 7b4113dd9d2255196268627eda845367 185 SUPERFAMILY SSF47413 7 74 2.95E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS05360 7b4113dd9d2255196268627eda845367 185 Gene3D G3DSA:2.60.120.10 76 184 2.5E-13 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS05360 7b4113dd9d2255196268627eda845367 185 Gene3D G3DSA:1.10.260.40 5 75 1.6E-15 T 28-03-2018 CU254_RS05360 7b4113dd9d2255196268627eda845367 185 SUPERFAMILY SSF51182 60 183 3.82E-20 T 28-03-2018 IPR011051 RmlC-like cupin domain CU254_RS05360 7b4113dd9d2255196268627eda845367 185 SMART SM00530 12 67 8.2E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS05360 7b4113dd9d2255196268627eda845367 185 Pfam PF07883 Cupin domain 112 181 1.7E-6 T 28-03-2018 IPR013096 Cupin 2, conserved barrel CU254_RS42175 22e804a569801fe393387dfdc39624ee 397 Gene3D G3DSA:1.20.1250.20 196 389 2.4E-9 T 28-03-2018 CU254_RS42175 22e804a569801fe393387dfdc39624ee 397 Gene3D G3DSA:1.20.1250.20 1 183 3.5E-9 T 28-03-2018 CU254_RS42175 22e804a569801fe393387dfdc39624ee 397 Pfam PF05977 Transmembrane secretion effector 1 388 4.4E-22 T 28-03-2018 IPR010290 Transmembrane secretion effector CU254_RS42175 22e804a569801fe393387dfdc39624ee 397 SUPERFAMILY SSF103473 7 385 5.23E-23 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS30505 8a316da39c9e5ec8d99af7a5b45cfc22 488 Pfam PF07364 Metallopeptidase family M81 5 283 4.7E-109 T 28-03-2018 IPR015995 Microcystin LR degradation protein MlrC, N-terminal CU254_RS30505 8a316da39c9e5ec8d99af7a5b45cfc22 488 Pfam PF07171 MlrC C-terminus 293 460 8.8E-55 T 28-03-2018 IPR010799 Microcystin LR degradation protein MlrC, C-terminal CU254_RS30505 8a316da39c9e5ec8d99af7a5b45cfc22 488 PIRSF PIRSF012702 1 480 1.8E-150 T 28-03-2018 IPR009197 Microcystin LR degradation protein MlrC CU254_RS38410 3bda5e68d03628f22f0ec4896b9a37a2 457 ProSitePatterns PS00218 Amino acid permeases signature. 42 72 - T 28-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CU254_RS38410 3bda5e68d03628f22f0ec4896b9a37a2 457 PIRSF PIRSF006060 1 455 2.9E-66 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CU254_RS38410 3bda5e68d03628f22f0ec4896b9a37a2 457 Pfam PF00324 Amino acid permease 17 443 1.1E-97 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CU254_RS11160 9d8852dd4e69107deed063c82742f507 530 Pfam PF13556 PucR C-terminal helix-turn-helix domain 475 530 7.9E-17 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CU254_RS11160 9d8852dd4e69107deed063c82742f507 530 Gene3D G3DSA:1.10.10.60 426 507 9.5E-5 T 28-03-2018 CU254_RS26585 c91098be7c4bfa6ce8b1e66b7da0b06a 405 SMART SM00729 28 253 1.4E-54 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CU254_RS26585 c91098be7c4bfa6ce8b1e66b7da0b06a 405 Pfam PF04055 Radical SAM superfamily 33 208 3.0E-19 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CU254_RS26585 c91098be7c4bfa6ce8b1e66b7da0b06a 405 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 31 362 4.9E-74 T 28-03-2018 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 CU254_RS26585 c91098be7c4bfa6ce8b1e66b7da0b06a 405 SUPERFAMILY SSF102114 13 403 6.93E-107 T 28-03-2018 CU254_RS26585 c91098be7c4bfa6ce8b1e66b7da0b06a 405 Gene3D G3DSA:3.20.20.70 26 345 5.4E-48 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS33070 86e9a5ec80783623b9a010b6b31931e9 440 Pfam PF01425 Amidase 22 424 1.7E-69 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS33070 86e9a5ec80783623b9a010b6b31931e9 440 SUPERFAMILY SSF75304 3 433 2.22E-94 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS33070 86e9a5ec80783623b9a010b6b31931e9 440 Gene3D G3DSA:3.90.1300.10 1 440 7.4E-97 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS31220 6f82672ff4c9b620dc8e018d0c07064d 268 Gene3D G3DSA:3.90.25.10 126 259 1.4E-5 T 28-03-2018 CU254_RS31220 6f82672ff4c9b620dc8e018d0c07064d 268 Pfam PF05368 NmrA-like family 118 203 4.6E-5 T 28-03-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 CU254_RS31220 6f82672ff4c9b620dc8e018d0c07064d 268 SUPERFAMILY SSF51735 4 260 1.56E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS31220 6f82672ff4c9b620dc8e018d0c07064d 268 Gene3D G3DSA:3.40.50.720 2 125 3.5E-12 T 28-03-2018 CU254_RS08370 99bd7274df8e69e1a3045bc922095475 284 Gene3D G3DSA:3.40.630.30 7 283 1.8E-18 T 28-03-2018 CU254_RS08370 99bd7274df8e69e1a3045bc922095475 284 Pfam PF08445 FR47-like protein 214 277 1.0E-8 T 28-03-2018 IPR013653 FR47-like GO:0016747 CU254_RS08370 99bd7274df8e69e1a3045bc922095475 284 SUPERFAMILY SSF55729 77 279 8.11E-19 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS08370 99bd7274df8e69e1a3045bc922095475 284 Pfam PF13312 Domain of unknown function (DUF4081) 48 156 2.8E-40 T 28-03-2018 IPR025289 Domain of unknown function DUF4081 CU254_RS08370 99bd7274df8e69e1a3045bc922095475 284 PIRSF PIRSF021603 2 284 1.2E-118 T 28-03-2018 IPR016794 Uncharacterised conserved protein UCP21603, acetyltransferase-like CU254_RS02740 9f154eb50c893a7965dbc52a368fa57a 243 SMART SM00849 19 191 9.2E-7 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS02740 9f154eb50c893a7965dbc52a368fa57a 243 SUPERFAMILY SSF56281 3 240 2.49E-47 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS02740 9f154eb50c893a7965dbc52a368fa57a 243 Pfam PF12706 Beta-lactamase superfamily domain 41 210 2.0E-23 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS02740 9f154eb50c893a7965dbc52a368fa57a 243 Gene3D G3DSA:3.60.15.10 2 242 5.9E-43 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS17695 a47c89542916d240408a91467e59aa24 323 SUPERFAMILY SSF50129 1 142 2.43E-28 T 28-03-2018 IPR011032 GroES-like CU254_RS17695 a47c89542916d240408a91467e59aa24 323 Gene3D G3DSA:3.40.50.720 138 291 1.5E-20 T 28-03-2018 CU254_RS17695 a47c89542916d240408a91467e59aa24 323 SUPERFAMILY SSF51735 124 286 4.49E-26 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS17695 a47c89542916d240408a91467e59aa24 323 Gene3D G3DSA:3.90.180.10 1 137 5.9E-25 T 28-03-2018 CU254_RS17695 a47c89542916d240408a91467e59aa24 323 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 89 3.5E-6 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CU254_RS17695 a47c89542916d240408a91467e59aa24 323 SMART SM00829 10 321 9.9E-12 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CU254_RS17695 a47c89542916d240408a91467e59aa24 323 Pfam PF13602 Zinc-binding dehydrogenase 184 321 4.9E-13 T 28-03-2018 CU254_RS11225 7ec30daef16a26ea8317456ec66d05a8 347 Gene3D G3DSA:3.40.50.300 45 213 4.4E-7 T 28-03-2018 CU254_RS11225 7ec30daef16a26ea8317456ec66d05a8 347 SUPERFAMILY SSF52540 81 216 1.33E-9 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS11225 7ec30daef16a26ea8317456ec66d05a8 347 Pfam PF03969 AFG1-like ATPase 42 222 5.5E-42 T 28-03-2018 IPR005654 ATPase, AFG1-like GO:0005524 CU254_RS11225 7ec30daef16a26ea8317456ec66d05a8 347 Pfam PF03969 AFG1-like ATPase 236 337 2.9E-13 T 28-03-2018 IPR005654 ATPase, AFG1-like GO:0005524 CU254_RS42380 ed74f73757f544fc568c9312d93e6b32 349 Pfam PF02195 ParB-like nuclease domain 58 158 9.9E-11 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CU254_RS42380 ed74f73757f544fc568c9312d93e6b32 349 SMART SM00470 56 159 2.6E-5 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CU254_RS42380 ed74f73757f544fc568c9312d93e6b32 349 Gene3D G3DSA:1.10.10.730 160 206 7.7E-5 T 28-03-2018 CU254_RS42380 ed74f73757f544fc568c9312d93e6b32 349 SUPERFAMILY SSF110849 57 161 3.49E-12 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CU254_RS42380 ed74f73757f544fc568c9312d93e6b32 349 Gene3D G3DSA:3.90.1530.10 44 159 1.6E-21 T 28-03-2018 CU254_RS42380 ed74f73757f544fc568c9312d93e6b32 349 SUPERFAMILY SSF109709 153 235 3.92E-13 T 28-03-2018 CU254_RS24245 747b2f123d5ef130ee3087e6f643d5a9 302 Gene3D G3DSA:1.10.287.1060 2 100 1.5E-5 T 28-03-2018 CU254_RS09295 bdb1516e6cf3cf34d4e0379377642b03 257 Pfam PF00977 Histidine biosynthesis protein 6 241 1.2E-85 T 28-03-2018 IPR006062 Histidine biosynthesis GO:0000105 CU254_RS09295 bdb1516e6cf3cf34d4e0379377642b03 257 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 3 257 4.0E-112 T 28-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 CU254_RS09295 bdb1516e6cf3cf34d4e0379377642b03 257 Gene3D G3DSA:3.20.20.70 5 253 9.0E-69 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS09295 bdb1516e6cf3cf34d4e0379377642b03 257 SUPERFAMILY SSF51366 4 256 3.45E-79 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CU254_RS09295 bdb1516e6cf3cf34d4e0379377642b03 257 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 2 257 47.923 T 28-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 CU254_RS20700 8ee374b5dacc017158c110d778ff1f8a 377 Pfam PF13556 PucR C-terminal helix-turn-helix domain 317 373 3.6E-18 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CU254_RS20700 8ee374b5dacc017158c110d778ff1f8a 377 Gene3D G3DSA:1.10.10.60 261 353 5.6E-8 T 28-03-2018 CU254_RS20795 5930fc30e5a1e66b98f31297864fd93e 136 SUPERFAMILY SSF55811 8 127 6.23E-19 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CU254_RS20795 5930fc30e5a1e66b98f31297864fd93e 136 Gene3D G3DSA:3.90.79.10 2 128 1.9E-17 T 28-03-2018 CU254_RS20795 5930fc30e5a1e66b98f31297864fd93e 136 Pfam PF00293 NUDIX domain 12 110 2.2E-10 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CU254_RS08060 f0249d57d676b696866cd1d99ab9558d 185 SUPERFAMILY SSF55194 3 184 3.14E-70 T 28-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 CU254_RS08060 f0249d57d676b696866cd1d99ab9558d 185 Pfam PF01765 Ribosome recycling factor 21 183 5.2E-63 T 28-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 CU254_RS08060 f0249d57d676b696866cd1d99ab9558d 185 Gene3D G3DSA:1.10.132.20 74 184 1.1E-36 T 28-03-2018 CU254_RS08060 f0249d57d676b696866cd1d99ab9558d 185 Gene3D G3DSA:1.10.132.20 2 73 4.7E-11 T 28-03-2018 CU254_RS08060 f0249d57d676b696866cd1d99ab9558d 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 10 185 2.7E-66 T 28-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 CU254_RS08060 f0249d57d676b696866cd1d99ab9558d 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 27.326 T 28-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 CU254_RS01005 16f84f7bb51906259a5a86c694382def 273 Pfam PF12697 Alpha/beta hydrolase family 26 261 4.2E-21 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS01005 16f84f7bb51906259a5a86c694382def 273 SUPERFAMILY SSF53474 8 268 1.08E-48 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS01005 16f84f7bb51906259a5a86c694382def 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 95 108 8.3E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS01005 16f84f7bb51906259a5a86c694382def 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 51 66 8.3E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS01005 16f84f7bb51906259a5a86c694382def 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 214 228 8.3E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS01005 16f84f7bb51906259a5a86c694382def 273 Gene3D G3DSA:3.40.50.1820 1 273 9.4E-43 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS01005 16f84f7bb51906259a5a86c694382def 273 PRINTS PR00412 Epoxide hydrolase signature 51 66 3.7E-8 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS01005 16f84f7bb51906259a5a86c694382def 273 PRINTS PR00412 Epoxide hydrolase signature 212 228 3.7E-8 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS01005 16f84f7bb51906259a5a86c694382def 273 PRINTS PR00412 Epoxide hydrolase signature 30 48 3.7E-8 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS01005 16f84f7bb51906259a5a86c694382def 273 PRINTS PR00412 Epoxide hydrolase signature 245 267 3.7E-8 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS01005 16f84f7bb51906259a5a86c694382def 273 PRINTS PR00412 Epoxide hydrolase signature 95 108 3.7E-8 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS38945 99e10331758501c15940cc0ba7429656 175 Hamap MF_00984 Single-stranded DNA-binding protein. 4 113 30.987 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CU254_RS38945 99e10331758501c15940cc0ba7429656 175 Gene3D G3DSA:2.40.50.140 1 120 6.4E-40 T 28-03-2018 CU254_RS38945 99e10331758501c15940cc0ba7429656 175 Pfam PF00436 Single-strand binding protein family 7 106 6.1E-30 T 28-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 CU254_RS38945 99e10331758501c15940cc0ba7429656 175 SUPERFAMILY SSF50249 6 175 5.63E-47 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CU254_RS38945 99e10331758501c15940cc0ba7429656 175 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 5 121 1.7E-33 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CU254_RS01160 276413c4fcd69d8b33ad0437a1d19cf5 323 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 296 315 1.8E-57 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CU254_RS01160 276413c4fcd69d8b33ad0437a1d19cf5 323 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 266 281 1.8E-57 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CU254_RS01160 276413c4fcd69d8b33ad0437a1d19cf5 323 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 190 209 1.8E-57 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CU254_RS01160 276413c4fcd69d8b33ad0437a1d19cf5 323 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 241 257 1.8E-57 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CU254_RS01160 276413c4fcd69d8b33ad0437a1d19cf5 323 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 121 135 1.8E-57 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CU254_RS01160 276413c4fcd69d8b33ad0437a1d19cf5 323 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 152 171 1.8E-57 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CU254_RS01160 276413c4fcd69d8b33ad0437a1d19cf5 323 Gene3D G3DSA:3.20.20.70 1 323 7.6E-143 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS01160 276413c4fcd69d8b33ad0437a1d19cf5 323 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 241 253 - T 28-03-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CU254_RS01160 276413c4fcd69d8b33ad0437a1d19cf5 323 Pfam PF00490 Delta-aminolevulinic acid dehydratase 5 321 1.3E-135 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CU254_RS01160 276413c4fcd69d8b33ad0437a1d19cf5 323 SMART SM01004 2 322 1.8E-212 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CU254_RS01160 276413c4fcd69d8b33ad0437a1d19cf5 323 SUPERFAMILY SSF51569 2 323 6.01E-129 T 28-03-2018 CU254_RS01160 276413c4fcd69d8b33ad0437a1d19cf5 323 PIRSF PIRSF001415 1 323 2.6E-141 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CU254_RS06915 8c9da300222306ca5dedd650350ba34c 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 3.3E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS06915 8c9da300222306ca5dedd650350ba34c 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 3.3E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS06915 8c9da300222306ca5dedd650350ba34c 199 Gene3D G3DSA:1.10.357.10 2 192 1.1E-34 T 28-03-2018 CU254_RS06915 8c9da300222306ca5dedd650350ba34c 199 SUPERFAMILY SSF46689 5 84 3.04E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS06915 8c9da300222306ca5dedd650350ba34c 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 63 1.3E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS06915 8c9da300222306ca5dedd650350ba34c 199 SUPERFAMILY SSF48498 82 186 2.3E-12 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS33220 b62cdd2738730f39ac86a67af4a8074a 401 Pfam PF01270 Glycosyl hydrolases family 8 53 393 8.5E-20 T 28-03-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 CU254_RS33220 b62cdd2738730f39ac86a67af4a8074a 401 PRINTS PR00735 Glycosyl hydrolase family 8 signature 381 395 8.9E-16 T 28-03-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 CU254_RS33220 b62cdd2738730f39ac86a67af4a8074a 401 PRINTS PR00735 Glycosyl hydrolase family 8 signature 91 104 8.9E-16 T 28-03-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 CU254_RS33220 b62cdd2738730f39ac86a67af4a8074a 401 PRINTS PR00735 Glycosyl hydrolase family 8 signature 283 292 8.9E-16 T 28-03-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 CU254_RS33220 b62cdd2738730f39ac86a67af4a8074a 401 PRINTS PR00735 Glycosyl hydrolase family 8 signature 154 172 8.9E-16 T 28-03-2018 IPR002037 Glycoside hydrolase, family 8 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 CU254_RS33220 b62cdd2738730f39ac86a67af4a8074a 401 Gene3D G3DSA:1.50.10.10 34 401 2.1E-81 T 28-03-2018 CU254_RS33220 b62cdd2738730f39ac86a67af4a8074a 401 SUPERFAMILY SSF48208 45 400 3.88E-65 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CU254_RS11710 d438651bc7a83fce9274b5460c9bea18 256 SUPERFAMILY SSF100950 5 249 1.26E-66 T 28-03-2018 CU254_RS11710 d438651bc7a83fce9274b5460c9bea18 256 TIGRFAM TIGR01198 pgl: 6-phosphogluconolactonase 8 247 3.9E-73 T 28-03-2018 IPR005900 6-phosphogluconolactonase, DevB-type GO:0005975|GO:0006098|GO:0017057 KEGG: 00030+3.1.1.31 CU254_RS11710 d438651bc7a83fce9274b5460c9bea18 256 Gene3D G3DSA:3.40.50.1360 1 252 1.5E-80 T 28-03-2018 CU254_RS11710 d438651bc7a83fce9274b5460c9bea18 256 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 11 237 1.5E-74 T 28-03-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 CU254_RS15785 6d4de71ee605e5ecbf5a37e540d8df8e 296 SUPERFAMILY SSF53474 25 295 1.0E-44 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS15785 6d4de71ee605e5ecbf5a37e540d8df8e 296 Pfam PF07859 alpha/beta hydrolase fold 76 276 8.3E-40 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CU254_RS15785 6d4de71ee605e5ecbf5a37e540d8df8e 296 Gene3D G3DSA:3.40.50.1820 7 296 1.4E-40 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS15920 bb199ad882fa143f7f4b6a35dbfee8bd 126 SUPERFAMILY SSF46785 8 103 4.13E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS15920 bb199ad882fa143f7f4b6a35dbfee8bd 126 Pfam PF12840 Helix-turn-helix domain 22 78 9.2E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS15920 bb199ad882fa143f7f4b6a35dbfee8bd 126 Gene3D G3DSA:1.10.10.10 7 108 4.7E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS15920 bb199ad882fa143f7f4b6a35dbfee8bd 126 SMART SM00418 21 99 3.5E-27 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS15920 bb199ad882fa143f7f4b6a35dbfee8bd 126 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 55 70 1.1E-13 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS15920 bb199ad882fa143f7f4b6a35dbfee8bd 126 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 23 38 1.1E-13 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS15920 bb199ad882fa143f7f4b6a35dbfee8bd 126 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 70 85 1.1E-13 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS19500 4969b266c21c193e5c6b23e3fbd71f99 342 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 138 340 1.8E-39 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS19500 4969b266c21c193e5c6b23e3fbd71f99 342 Gene3D G3DSA:1.10.3720.10 25 329 3.9E-38 T 28-03-2018 CU254_RS19500 4969b266c21c193e5c6b23e3fbd71f99 342 SUPERFAMILY SSF161098 115 328 1.57E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS19170 259b281e591ea2eeef863d2e2da2399a 231 SUPERFAMILY SSF48498 83 228 2.33E-18 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS19170 259b281e591ea2eeef863d2e2da2399a 231 Gene3D G3DSA:1.10.357.10 75 231 3.7E-28 T 28-03-2018 CU254_RS19170 259b281e591ea2eeef863d2e2da2399a 231 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 84 225 3.2E-9 T 28-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 CU254_RS19170 259b281e591ea2eeef863d2e2da2399a 231 SUPERFAMILY SSF46689 10 75 1.44E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS19170 259b281e591ea2eeef863d2e2da2399a 231 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 66 1.4E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS19170 259b281e591ea2eeef863d2e2da2399a 231 Gene3D G3DSA:1.10.10.60 1 70 8.5E-14 T 28-03-2018 CU254_RS07515 dbd0c648600d192249c3b9a39631b7be 195 Gene3D G3DSA:1.10.10.10 104 193 2.5E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS07515 dbd0c648600d192249c3b9a39631b7be 195 SUPERFAMILY SSF88659 106 192 3.36E-16 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS07515 dbd0c648600d192249c3b9a39631b7be 195 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 27 189 1.6E-23 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS07515 dbd0c648600d192249c3b9a39631b7be 195 Pfam PF04542 Sigma-70 region 2 35 101 2.8E-9 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS07515 dbd0c648600d192249c3b9a39631b7be 195 Gene3D G3DSA:1.10.1740.10 8 103 2.9E-17 T 28-03-2018 CU254_RS07515 dbd0c648600d192249c3b9a39631b7be 195 Pfam PF08281 Sigma-70, region 4 135 186 5.0E-11 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS07515 dbd0c648600d192249c3b9a39631b7be 195 SUPERFAMILY SSF88946 8 117 7.59E-17 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS12445 a64b0b1d4df8f86be2d3780bed465aaa 438 SUPERFAMILY SSF75304 2 432 5.49E-137 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS12445 a64b0b1d4df8f86be2d3780bed465aaa 438 Pfam PF01425 Amidase 24 423 1.2E-113 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS12445 a64b0b1d4df8f86be2d3780bed465aaa 438 Gene3D G3DSA:3.90.1300.10 1 436 2.5E-140 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS12445 a64b0b1d4df8f86be2d3780bed465aaa 438 ProSitePatterns PS00571 Amidases signature. 141 172 - T 28-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CU254_RS20555 f2dc1fd701fe3390cc4c9f48c2d12cb7 204 Gene3D G3DSA:1.10.10.60 10 64 2.7E-17 T 28-03-2018 CU254_RS20555 f2dc1fd701fe3390cc4c9f48c2d12cb7 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 1.3E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS20555 f2dc1fd701fe3390cc4c9f48c2d12cb7 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 1.3E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS20555 f2dc1fd701fe3390cc4c9f48c2d12cb7 204 ProSitePatterns PS01081 TetR-type HTH domain signature. 28 58 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CU254_RS20555 f2dc1fd701fe3390cc4c9f48c2d12cb7 204 SUPERFAMILY SSF46689 6 85 3.69E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS20555 f2dc1fd701fe3390cc4c9f48c2d12cb7 204 SUPERFAMILY SSF48498 81 190 8.6E-8 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS20555 f2dc1fd701fe3390cc4c9f48c2d12cb7 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 60 6.3E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS20555 f2dc1fd701fe3390cc4c9f48c2d12cb7 204 Gene3D G3DSA:1.10.357.10 65 195 5.5E-11 T 28-03-2018 CU254_RS34715 6e071953c2b992114975bea8e23966f6 303 SUPERFAMILY SSF161098 55 291 7.06E-43 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS34715 6e071953c2b992114975bea8e23966f6 303 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 292 4.0E-8 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS34715 6e071953c2b992114975bea8e23966f6 303 Gene3D G3DSA:1.10.3720.10 62 299 1.6E-35 T 28-03-2018 CU254_RS34715 6e071953c2b992114975bea8e23966f6 303 Gene3D G3DSA:1.20.58.370 3 42 8.8E-4 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain CU254_RS13285 f45917df340b89289f07bf99696fee21 333 Pfam PF13407 Periplasmic binding protein domain 50 301 8.6E-47 T 28-03-2018 IPR025997 Periplasmic binding protein CU254_RS13285 f45917df340b89289f07bf99696fee21 333 SUPERFAMILY SSF53822 47 327 6.13E-68 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CU254_RS13285 f45917df340b89289f07bf99696fee21 333 Gene3D G3DSA:3.40.50.2300 154 333 4.7E-38 T 28-03-2018 CU254_RS13285 f45917df340b89289f07bf99696fee21 333 Gene3D G3DSA:3.40.50.2300 45 153 4.6E-19 T 28-03-2018 CU254_RS06900 7eea2f0e9f1a57fe87d13004511eaf56 448 Pfam PF12796 Ankyrin repeats (3 copies) 321 419 6.5E-12 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain CU254_RS06900 7eea2f0e9f1a57fe87d13004511eaf56 448 Pfam PF12796 Ankyrin repeats (3 copies) 177 257 3.7E-8 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain CU254_RS06900 7eea2f0e9f1a57fe87d13004511eaf56 448 SUPERFAMILY SSF48403 144 269 7.72E-34 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain CU254_RS06900 7eea2f0e9f1a57fe87d13004511eaf56 448 SUPERFAMILY SSF48403 321 444 7.72E-34 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain CU254_RS06900 7eea2f0e9f1a57fe87d13004511eaf56 448 Gene3D G3DSA:1.25.40.20 136 276 2.2E-20 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain CU254_RS06900 7eea2f0e9f1a57fe87d13004511eaf56 448 SMART SM00248 235 264 93.0 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 CU254_RS06900 7eea2f0e9f1a57fe87d13004511eaf56 448 SMART SM00248 168 197 11.0 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 CU254_RS06900 7eea2f0e9f1a57fe87d13004511eaf56 448 SMART SM00248 348 377 18.0 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 CU254_RS06900 7eea2f0e9f1a57fe87d13004511eaf56 448 SMART SM00248 316 345 160.0 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 CU254_RS06900 7eea2f0e9f1a57fe87d13004511eaf56 448 SMART SM00248 388 417 2.1E-4 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 CU254_RS06900 7eea2f0e9f1a57fe87d13004511eaf56 448 SMART SM00248 201 230 0.17 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 CU254_RS06900 7eea2f0e9f1a57fe87d13004511eaf56 448 Gene3D G3DSA:1.25.40.20 295 445 2.7E-23 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain CU254_RS37055 af706d6e0beaeddce625ea2c929be00a 252 Gene3D G3DSA:3.90.550.10 6 236 1.2E-28 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS37055 af706d6e0beaeddce625ea2c929be00a 252 SUPERFAMILY SSF53448 13 220 3.99E-35 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS37055 af706d6e0beaeddce625ea2c929be00a 252 Pfam PF00535 Glycosyl transferase family 2 17 137 8.1E-24 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CU254_RS06980 73ca8322e2dc7475cc2c251e62045d42 347 Gene3D G3DSA:3.50.50.60 1 347 8.5E-36 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS06980 73ca8322e2dc7475cc2c251e62045d42 347 Pfam PF01494 FAD binding domain 2 328 1.3E-20 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CU254_RS06980 73ca8322e2dc7475cc2c251e62045d42 347 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 274 289 2.6E-15 T 28-03-2018 CU254_RS06980 73ca8322e2dc7475cc2c251e62045d42 347 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 2.6E-15 T 28-03-2018 CU254_RS06980 73ca8322e2dc7475cc2c251e62045d42 347 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 289 305 2.6E-15 T 28-03-2018 CU254_RS06980 73ca8322e2dc7475cc2c251e62045d42 347 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 141 156 2.6E-15 T 28-03-2018 CU254_RS06980 73ca8322e2dc7475cc2c251e62045d42 347 SUPERFAMILY SSF51905 1 162 7.53E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS06980 73ca8322e2dc7475cc2c251e62045d42 347 SUPERFAMILY SSF51905 261 344 7.53E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS23690 043a949eadde3eaf87e89e08cb8facb7 300 Gene3D G3DSA:1.10.260.40 4 93 2.6E-11 T 28-03-2018 CU254_RS23690 043a949eadde3eaf87e89e08cb8facb7 300 SMART SM00530 11 84 1.2E-4 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS23690 043a949eadde3eaf87e89e08cb8facb7 300 SUPERFAMILY SSF47413 33 81 6.95E-6 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS23690 043a949eadde3eaf87e89e08cb8facb7 300 Pfam PF13560 Helix-turn-helix domain 33 86 6.6E-12 T 28-03-2018 CU254_RS23300 16fb380c68b8aaf524d772d45df8f9b0 280 SMART SM00530 14 69 4.6E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS23300 16fb380c68b8aaf524d772d45df8f9b0 280 Pfam PF01381 Helix-turn-helix 15 69 1.9E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS23300 16fb380c68b8aaf524d772d45df8f9b0 280 Gene3D G3DSA:1.10.10.60 77 141 1.1E-16 T 28-03-2018 CU254_RS23300 16fb380c68b8aaf524d772d45df8f9b0 280 Pfam PF00440 Bacterial regulatory proteins, tetR family 99 144 5.7E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS23300 16fb380c68b8aaf524d772d45df8f9b0 280 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 119 142 1.9E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS23300 16fb380c68b8aaf524d772d45df8f9b0 280 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 98 111 1.9E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS23300 16fb380c68b8aaf524d772d45df8f9b0 280 SUPERFAMILY SSF48498 167 275 1.75E-15 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS23300 16fb380c68b8aaf524d772d45df8f9b0 280 SUPERFAMILY SSF46689 85 168 2.46E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS23300 16fb380c68b8aaf524d772d45df8f9b0 280 Gene3D G3DSA:1.10.357.10 142 280 1.9E-20 T 28-03-2018 CU254_RS23300 16fb380c68b8aaf524d772d45df8f9b0 280 SUPERFAMILY SSF47413 12 71 2.36E-13 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS23300 16fb380c68b8aaf524d772d45df8f9b0 280 Gene3D G3DSA:1.10.260.40 10 76 2.5E-17 T 28-03-2018 CU254_RS36875 c57784334ad86e1e0e8c04a85e2dd594 158 Gene3D G3DSA:1.20.1260.10 2 158 5.0E-40 T 28-03-2018 IPR012347 Ferritin-related CU254_RS36875 c57784334ad86e1e0e8c04a85e2dd594 158 ProSitePatterns PS00819 Dps protein family signature 2. 66 80 - T 28-03-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 CU254_RS36875 c57784334ad86e1e0e8c04a85e2dd594 158 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 40 56 1.2E-11 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CU254_RS36875 c57784334ad86e1e0e8c04a85e2dd594 158 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 64 80 1.2E-11 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CU254_RS36875 c57784334ad86e1e0e8c04a85e2dd594 158 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 135 153 1.2E-11 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CU254_RS36875 c57784334ad86e1e0e8c04a85e2dd594 158 SUPERFAMILY SSF47240 6 155 5.41E-45 T 28-03-2018 IPR009078 Ferritin-like superfamily CU254_RS36875 c57784334ad86e1e0e8c04a85e2dd594 158 PIRSF PIRSF005900 1 158 3.7E-44 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CU254_RS36875 c57784334ad86e1e0e8c04a85e2dd594 158 Pfam PF00210 Ferritin-like domain 20 156 5.3E-24 T 28-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 CU254_RS29955 f3e3ad2344af155806e996e5d5ecda02 265 Gene3D G3DSA:3.10.450.50 3 122 2.8E-13 T 28-03-2018 CU254_RS29955 f3e3ad2344af155806e996e5d5ecda02 265 SUPERFAMILY SSF54427 5 122 1.62E-24 T 28-03-2018 IPR032710 NTF2-like domain CU254_RS29955 f3e3ad2344af155806e996e5d5ecda02 265 SUPERFAMILY SSF54427 131 263 6.83E-24 T 28-03-2018 IPR032710 NTF2-like domain CU254_RS29955 f3e3ad2344af155806e996e5d5ecda02 265 Gene3D G3DSA:3.10.450.50 123 264 1.2E-20 T 28-03-2018 CU254_RS29955 f3e3ad2344af155806e996e5d5ecda02 265 Pfam PF12680 SnoaL-like domain 11 117 2.9E-9 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CU254_RS29955 f3e3ad2344af155806e996e5d5ecda02 265 Pfam PF12680 SnoaL-like domain 136 249 4.2E-11 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CU254_RS05365 4b192e126db1774b260771f932299dd1 472 PRINTS PR01036 Tetracycline resistance protein TetB signature 142 166 9.3E-6 T 28-03-2018 CU254_RS05365 4b192e126db1774b260771f932299dd1 472 PRINTS PR01036 Tetracycline resistance protein TetB signature 334 354 9.3E-6 T 28-03-2018 CU254_RS05365 4b192e126db1774b260771f932299dd1 472 PRINTS PR01036 Tetracycline resistance protein TetB signature 112 132 9.3E-6 T 28-03-2018 CU254_RS05365 4b192e126db1774b260771f932299dd1 472 Gene3D G3DSA:1.20.1250.20 4 203 7.0E-21 T 28-03-2018 CU254_RS05365 4b192e126db1774b260771f932299dd1 472 SUPERFAMILY SSF103473 248 441 1.83E-26 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS05365 4b192e126db1774b260771f932299dd1 472 SUPERFAMILY SSF103473 16 201 1.83E-26 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS05365 4b192e126db1774b260771f932299dd1 472 Gene3D G3DSA:1.20.1250.20 264 453 9.7E-5 T 28-03-2018 CU254_RS05365 4b192e126db1774b260771f932299dd1 472 Pfam PF07690 Major Facilitator Superfamily 26 406 2.7E-25 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS24915 fffa76cf70a31a8bc61b9691269f8623 273 Gene3D G3DSA:3.10.310.10 127 261 1.5E-33 T 28-03-2018 CU254_RS24915 fffa76cf70a31a8bc61b9691269f8623 273 Gene3D G3DSA:3.10.310.10 1 126 2.1E-31 T 28-03-2018 CU254_RS24915 fffa76cf70a31a8bc61b9691269f8623 273 SUPERFAMILY SSF54506 3 270 2.09E-66 T 28-03-2018 CU254_RS24915 fffa76cf70a31a8bc61b9691269f8623 273 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 1 269 3.3E-53 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CU254_RS24915 fffa76cf70a31a8bc61b9691269f8623 273 Pfam PF02567 Phenazine biosynthesis-like protein 7 265 1.4E-51 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CU254_RS24915 fffa76cf70a31a8bc61b9691269f8623 273 PIRSF PIRSF016184 1 272 3.9E-67 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CU254_RS38060 1e00ff9df95248f38624d1e19101aa78 205 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 49 201 1.6E-25 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS38060 1e00ff9df95248f38624d1e19101aa78 205 Gene3D G3DSA:1.10.10.10 116 204 1.2E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS38060 1e00ff9df95248f38624d1e19101aa78 205 SUPERFAMILY SSF88946 49 124 8.63E-15 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS38060 1e00ff9df95248f38624d1e19101aa78 205 SUPERFAMILY SSF88659 131 202 2.43E-17 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS38060 1e00ff9df95248f38624d1e19101aa78 205 Pfam PF04542 Sigma-70 region 2 52 118 3.4E-9 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS38060 1e00ff9df95248f38624d1e19101aa78 205 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 49 202 2.5E-46 T 28-03-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 CU254_RS38060 1e00ff9df95248f38624d1e19101aa78 205 Gene3D G3DSA:1.10.1740.10 44 115 8.2E-14 T 28-03-2018 CU254_RS38060 1e00ff9df95248f38624d1e19101aa78 205 Pfam PF08281 Sigma-70, region 4 145 197 4.4E-18 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS23890 547ee131f8fa4b9c64085ef344a5d79b 261 SUPERFAMILY SSF54637 8 144 1.23E-28 T 28-03-2018 IPR029069 HotDog domain CU254_RS23890 547ee131f8fa4b9c64085ef344a5d79b 261 Gene3D G3DSA:3.10.129.10 12 145 5.7E-23 T 28-03-2018 CU254_RS23890 547ee131f8fa4b9c64085ef344a5d79b 261 SUPERFAMILY SSF54637 157 257 1.49E-20 T 28-03-2018 IPR029069 HotDog domain CU254_RS23890 547ee131f8fa4b9c64085ef344a5d79b 261 Gene3D G3DSA:3.10.129.10 146 260 6.5E-20 T 28-03-2018 CU254_RS23890 547ee131f8fa4b9c64085ef344a5d79b 261 Pfam PF01575 MaoC like domain 151 241 1.1E-17 T 28-03-2018 IPR002539 MaoC-like domain CU254_RS17960 835cfe2c774391a1849940c97a67a99b 542 Pfam PF08386 TAP-like protein 426 527 6.4E-19 T 28-03-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal CU254_RS17960 835cfe2c774391a1849940c97a67a99b 542 Gene3D G3DSA:3.40.50.1820 59 519 1.1E-34 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS17960 835cfe2c774391a1849940c97a67a99b 542 SUPERFAMILY SSF53474 205 259 5.27E-22 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS17960 835cfe2c774391a1849940c97a67a99b 542 SUPERFAMILY SSF53474 381 502 5.27E-22 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS17960 835cfe2c774391a1849940c97a67a99b 542 SUPERFAMILY SSF53474 106 158 5.27E-22 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS17960 835cfe2c774391a1849940c97a67a99b 542 Pfam PF00561 alpha/beta hydrolase fold 108 293 1.3E-22 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS00580 4f2aca84a5835df4bbba77a0924c92a7 310 Gene3D G3DSA:3.40.190.10 222 305 5.6E-15 T 28-03-2018 CU254_RS00580 4f2aca84a5835df4bbba77a0924c92a7 310 SMART SM00062 76 298 2.1E-62 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CU254_RS00580 4f2aca84a5835df4bbba77a0924c92a7 310 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 77 296 6.9E-50 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CU254_RS00580 4f2aca84a5835df4bbba77a0924c92a7 310 Gene3D G3DSA:3.40.190.10 65 221 7.2E-36 T 28-03-2018 CU254_RS00580 4f2aca84a5835df4bbba77a0924c92a7 310 SUPERFAMILY SSF53850 66 296 3.98E-55 T 28-03-2018 CU254_RS35055 b631b27358e6fcf8a45698f23f471ea1 273 SUPERFAMILY SSF55315 8 107 1.88E-10 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CU254_RS35055 b631b27358e6fcf8a45698f23f471ea1 273 SUPERFAMILY SSF75217 97 266 1.24E-37 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CU254_RS35055 b631b27358e6fcf8a45698f23f471ea1 273 Pfam PF00588 SpoU rRNA Methylase family 120 262 8.4E-29 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CU254_RS35055 b631b27358e6fcf8a45698f23f471ea1 273 Gene3D G3DSA:3.40.1280.10 108 269 9.9E-43 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CU254_RS35055 b631b27358e6fcf8a45698f23f471ea1 273 Gene3D G3DSA:3.30.1330.30 7 107 9.9E-20 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CU254_RS28575 5ad676e7c7c354f8417eb741efc86c64 79 SUPERFAMILY SSF47413 4 66 8.31E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS28575 5ad676e7c7c354f8417eb741efc86c64 79 Pfam PF01381 Helix-turn-helix 12 61 8.5E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS28575 5ad676e7c7c354f8417eb741efc86c64 79 SMART SM00530 8 63 8.7E-15 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS28575 5ad676e7c7c354f8417eb741efc86c64 79 Gene3D G3DSA:1.10.260.40 1 78 2.6E-16 T 28-03-2018 CU254_RS27315 d8906bb612eda935d168bbfd7f6392dd 441 Gene3D G3DSA:2.140.10.10 27 242 7.9E-12 T 28-03-2018 CU254_RS27315 d8906bb612eda935d168bbfd7f6392dd 441 Gene3D G3DSA:2.140.10.10 327 431 2.8E-7 T 28-03-2018 CU254_RS27315 d8906bb612eda935d168bbfd7f6392dd 441 Gene3D G3DSA:2.140.10.10 243 326 0.0043 T 28-03-2018 CU254_RS27315 d8906bb612eda935d168bbfd7f6392dd 441 SUPERFAMILY SSF50998 98 126 9.76E-16 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CU254_RS27315 d8906bb612eda935d168bbfd7f6392dd 441 SUPERFAMILY SSF50998 154 409 9.76E-16 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CU254_RS27315 d8906bb612eda935d168bbfd7f6392dd 441 Pfam PF13360 PQQ-like domain 224 407 7.3E-14 T 28-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat CU254_RS28580 f2ce74f02f42ac9d7c94940fed60fa75 1201 TIGRFAM TIGR02257 cobalto_cobN: cobaltochelatase, CobN subunit 40 1193 0.0 T 28-03-2018 IPR011953 Cobaltochelatase, CobN subunit GO:0009236|GO:0051116 CU254_RS28580 f2ce74f02f42ac9d7c94940fed60fa75 1201 Pfam PF02514 CobN/Magnesium Chelatase 100 1182 0.0 T 28-03-2018 IPR003672 CobN/magnesium chelatase GO:0009058 CU254_RS28580 f2ce74f02f42ac9d7c94940fed60fa75 1201 Gene3D G3DSA:3.20.20.70 38 133 0.2 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS19630 85982f87b6374cdd25e78d79fa6b9428 234 TIGRFAM TIGR03848 MSMEG_4193: probable phosphomutase, MSMEG_4193 family 3 205 4.7E-99 T 28-03-2018 IPR022492 Phosphomutase MSMEG4193, putative CU254_RS19630 85982f87b6374cdd25e78d79fa6b9428 234 Gene3D G3DSA:3.40.50.1240 1 204 3.0E-40 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CU254_RS19630 85982f87b6374cdd25e78d79fa6b9428 234 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 200 5.5E-47 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CU254_RS19630 85982f87b6374cdd25e78d79fa6b9428 234 SUPERFAMILY SSF53254 3 200 1.56E-42 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CU254_RS19630 85982f87b6374cdd25e78d79fa6b9428 234 SMART SM00855 3 161 8.4E-20 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CU254_RS23970 a0617bf3d8b94d54a76e5831e634ba73 215 Pfam PF01613 Flavin reductase like domain 15 185 3.3E-9 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CU254_RS23970 a0617bf3d8b94d54a76e5831e634ba73 215 SUPERFAMILY SSF50475 14 192 4.3E-29 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS23970 a0617bf3d8b94d54a76e5831e634ba73 215 Gene3D G3DSA:2.30.110.10 10 201 3.0E-32 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS37770 72701c2aaa6e1d0344da09cd732d134c 246 Pfam PF00005 ABC transporter 25 171 1.7E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS37770 72701c2aaa6e1d0344da09cd732d134c 246 SMART SM00382 34 219 9.6E-19 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS37770 72701c2aaa6e1d0344da09cd732d134c 246 SUPERFAMILY SSF52540 10 241 1.36E-74 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS37770 72701c2aaa6e1d0344da09cd732d134c 246 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS37770 72701c2aaa6e1d0344da09cd732d134c 246 PIRSF PIRSF039085 6 246 4.2E-99 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CU254_RS37770 72701c2aaa6e1d0344da09cd732d134c 246 Gene3D G3DSA:3.40.50.300 6 246 6.0E-77 T 28-03-2018 CU254_RS23485 45ac5d92eb294690ec23a6ad9dbea9a1 495 Gene3D G3DSA:3.50.50.60 16 394 1.1E-34 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS23485 45ac5d92eb294690ec23a6ad9dbea9a1 495 PRINTS PR00162 Rieske 2Fe-2S subunit signature 466 478 2.1E-8 T 28-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 CU254_RS23485 45ac5d92eb294690ec23a6ad9dbea9a1 495 PRINTS PR00162 Rieske 2Fe-2S subunit signature 478 490 2.1E-8 T 28-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 CU254_RS23485 45ac5d92eb294690ec23a6ad9dbea9a1 495 PRINTS PR00162 Rieske 2Fe-2S subunit signature 445 456 2.1E-8 T 28-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 CU254_RS23485 45ac5d92eb294690ec23a6ad9dbea9a1 495 SUPERFAMILY SSF51905 326 375 2.85E-32 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS23485 45ac5d92eb294690ec23a6ad9dbea9a1 495 SUPERFAMILY SSF51905 29 245 2.85E-32 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS23485 45ac5d92eb294690ec23a6ad9dbea9a1 495 SUPERFAMILY SSF50022 414 492 5.24E-23 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CU254_RS23485 45ac5d92eb294690ec23a6ad9dbea9a1 495 Pfam PF01266 FAD dependent oxidoreductase 30 365 7.0E-40 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CU254_RS23485 45ac5d92eb294690ec23a6ad9dbea9a1 495 Gene3D G3DSA:2.102.10.10 395 493 1.4E-20 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CU254_RS23485 45ac5d92eb294690ec23a6ad9dbea9a1 495 Pfam PF00355 Rieske [2Fe-2S] domain 433 491 1.3E-13 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CU254_RS05735 5d0cac0dd730eb8d7ce3873e10a19529 339 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 129 311 8.8E-54 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CU254_RS05735 5d0cac0dd730eb8d7ce3873e10a19529 339 SUPERFAMILY SSF51735 121 312 2.41E-53 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS05735 5d0cac0dd730eb8d7ce3873e10a19529 339 Gene3D G3DSA:3.40.50.720 136 314 1.3E-50 T 28-03-2018 CU254_RS05735 5d0cac0dd730eb8d7ce3873e10a19529 339 SUPERFAMILY SSF52283 23 154 5.1E-28 T 28-03-2018 CU254_RS05735 5d0cac0dd730eb8d7ce3873e10a19529 339 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 208 230 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CU254_RS05735 5d0cac0dd730eb8d7ce3873e10a19529 339 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 35 332 8.9E-17 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CU254_RS05735 5d0cac0dd730eb8d7ce3873e10a19529 339 Gene3D G3DSA:3.40.50.720 23 135 4.4E-17 T 28-03-2018 CU254_RS05735 5d0cac0dd730eb8d7ce3873e10a19529 339 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 237 253 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CU254_RS27925 8ede198cbfcfff441fa3a77cc91ed716 404 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 10 157 1.9E-12 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS27925 8ede198cbfcfff441fa3a77cc91ed716 404 SUPERFAMILY SSF88659 95 156 2.43E-8 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS27925 8ede198cbfcfff441fa3a77cc91ed716 404 Pfam PF08281 Sigma-70, region 4 105 154 2.4E-8 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS27925 8ede198cbfcfff441fa3a77cc91ed716 404 Gene3D G3DSA:1.10.1740.10 2 75 4.3E-15 T 28-03-2018 CU254_RS27925 8ede198cbfcfff441fa3a77cc91ed716 404 Pfam PF04542 Sigma-70 region 2 11 75 4.2E-9 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS27925 8ede198cbfcfff441fa3a77cc91ed716 404 Gene3D G3DSA:1.10.10.10 76 158 7.0E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS27925 8ede198cbfcfff441fa3a77cc91ed716 404 SUPERFAMILY SSF88946 5 91 3.02E-12 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS27925 8ede198cbfcfff441fa3a77cc91ed716 404 Gene3D G3DSA:1.25.40.10 193 396 2.1E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS41195 f717223d91159ead4d3c95b628a6114f 334 SUPERFAMILY SSF50249 207 329 2.28E-26 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CU254_RS41195 f717223d91159ead4d3c95b628a6114f 334 SUPERFAMILY SSF56091 11 202 2.62E-37 T 28-03-2018 CU254_RS41195 f717223d91159ead4d3c95b628a6114f 334 Pfam PF01068 ATP dependent DNA ligase domain 30 202 3.4E-23 T 28-03-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 CU254_RS41195 f717223d91159ead4d3c95b628a6114f 334 TIGRFAM TIGR02779 NHEJ_ligase_lig: DNA ligase D, ligase domain 15 326 1.9E-69 T 28-03-2018 IPR014146 DNA ligase D, ligase domain CU254_RS41195 f717223d91159ead4d3c95b628a6114f 334 Gene3D G3DSA:3.30.1490.70 136 194 6.6E-10 T 28-03-2018 CU254_RS41195 f717223d91159ead4d3c95b628a6114f 334 Gene3D G3DSA:3.30.470.30 3 135 2.5E-32 T 28-03-2018 CU254_RS41195 f717223d91159ead4d3c95b628a6114f 334 Gene3D G3DSA:2.40.50.140 195 322 1.2E-25 T 28-03-2018 CU254_RS41195 f717223d91159ead4d3c95b628a6114f 334 Pfam PF04679 ATP dependent DNA ligase C terminal region 225 320 1.7E-21 T 28-03-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 CU254_RS25580 de20d345bb18d63fc673e84a7e9e8c82 326 SUPERFAMILY SSF51735 3 323 8.32E-92 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS25580 de20d345bb18d63fc673e84a7e9e8c82 326 Gene3D G3DSA:3.40.50.720 136 297 3.6E-35 T 28-03-2018 CU254_RS25580 de20d345bb18d63fc673e84a7e9e8c82 326 PIRSF PIRSF001439 1 325 9.8E-82 T 28-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CU254_RS25580 de20d345bb18d63fc673e84a7e9e8c82 326 Gene3D G3DSA:3.30.1780.10 1 135 3.4E-39 T 28-03-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 CU254_RS25580 de20d345bb18d63fc673e84a7e9e8c82 326 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 4 314 1.0E-79 T 28-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CU254_RS23515 c3a14b5edb6cd47890162756a3acc3c1 310 Pfam PF13602 Zinc-binding dehydrogenase 187 307 2.3E-9 T 28-03-2018 CU254_RS23515 c3a14b5edb6cd47890162756a3acc3c1 310 Gene3D G3DSA:3.90.180.10 1 145 4.9E-31 T 28-03-2018 CU254_RS23515 c3a14b5edb6cd47890162756a3acc3c1 310 SUPERFAMILY SSF50129 5 141 9.43E-20 T 28-03-2018 IPR011032 GroES-like CU254_RS23515 c3a14b5edb6cd47890162756a3acc3c1 310 Gene3D G3DSA:3.40.50.720 146 249 1.3E-17 T 28-03-2018 CU254_RS23515 c3a14b5edb6cd47890162756a3acc3c1 310 SMART SM00829 9 307 4.3E-8 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CU254_RS23515 c3a14b5edb6cd47890162756a3acc3c1 310 SUPERFAMILY SSF51735 112 240 5.51E-26 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS33840 04c86f1454de5a55229d564f1c145f2e 460 SMART SM01208 296 374 3.8E-24 T 28-03-2018 IPR011098 G5 domain CU254_RS33840 04c86f1454de5a55229d564f1c145f2e 460 SUPERFAMILY SSF53955 382 457 8.62E-28 T 28-03-2018 IPR023346 Lysozyme-like domain CU254_RS33840 04c86f1454de5a55229d564f1c145f2e 460 Pfam PF07501 G5 domain 302 373 2.9E-19 T 28-03-2018 IPR011098 G5 domain CU254_RS33840 04c86f1454de5a55229d564f1c145f2e 460 Pfam PF06737 Transglycosylase-like domain 385 456 2.0E-31 T 28-03-2018 IPR010618 Transglycosylase-like CU254_RS33840 04c86f1454de5a55229d564f1c145f2e 460 Pfam PF03990 Domain of unknown function (DUF348) 125 164 3.8E-14 T 28-03-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 CU254_RS33840 04c86f1454de5a55229d564f1c145f2e 460 Gene3D G3DSA:1.10.530.10 368 460 1.9E-29 T 28-03-2018 CU254_RS33840 04c86f1454de5a55229d564f1c145f2e 460 Gene3D G3DSA:2.20.230.10 295 367 5.9E-20 T 28-03-2018 CU254_RS10400 1e92ea2bc0f49735b1a243a9085e20ab 132 SUPERFAMILY SSF54637 4 127 2.54E-15 T 28-03-2018 IPR029069 HotDog domain CU254_RS10400 1e92ea2bc0f49735b1a243a9085e20ab 132 Pfam PF01575 MaoC like domain 25 100 6.2E-5 T 28-03-2018 IPR002539 MaoC-like domain CU254_RS10400 1e92ea2bc0f49735b1a243a9085e20ab 132 Gene3D G3DSA:3.10.129.10 2 128 7.1E-18 T 28-03-2018 CU254_RS27915 9866be0bafba9b0ae0c5f73f72d9812e 403 Pfam PF02371 Transposase IS116/IS110/IS902 family 271 356 7.6E-23 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CU254_RS27915 9866be0bafba9b0ae0c5f73f72d9812e 403 Gene3D G3DSA:3.30.420.40 4 267 7.8E-5 T 28-03-2018 CU254_RS27915 9866be0bafba9b0ae0c5f73f72d9812e 403 Pfam PF01548 Transposase 9 163 1.1E-43 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CU254_RS13895 9866be0bafba9b0ae0c5f73f72d9812e 403 Pfam PF02371 Transposase IS116/IS110/IS902 family 271 356 7.6E-23 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CU254_RS13895 9866be0bafba9b0ae0c5f73f72d9812e 403 Gene3D G3DSA:3.30.420.40 4 267 7.8E-5 T 28-03-2018 CU254_RS13895 9866be0bafba9b0ae0c5f73f72d9812e 403 Pfam PF01548 Transposase 9 163 1.1E-43 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CU254_RS20920 9866be0bafba9b0ae0c5f73f72d9812e 403 Pfam PF02371 Transposase IS116/IS110/IS902 family 271 356 7.6E-23 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CU254_RS20920 9866be0bafba9b0ae0c5f73f72d9812e 403 Gene3D G3DSA:3.30.420.40 4 267 7.8E-5 T 28-03-2018 CU254_RS20920 9866be0bafba9b0ae0c5f73f72d9812e 403 Pfam PF01548 Transposase 9 163 1.1E-43 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CU254_RS06760 a09f18d57d26bdc2a80cfbb1b9e32e96 150 SUPERFAMILY SSF55729 2 144 7.26E-30 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS06760 a09f18d57d26bdc2a80cfbb1b9e32e96 150 Gene3D G3DSA:3.40.630.30 2 145 4.8E-29 T 28-03-2018 CU254_RS06760 a09f18d57d26bdc2a80cfbb1b9e32e96 150 Pfam PF00583 Acetyltransferase (GNAT) family 35 139 2.5E-17 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS03900 337ec4ebe648b7a78d9f691c6e064a61 133 SUPERFAMILY SSF55811 4 124 2.17E-35 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CU254_RS03900 337ec4ebe648b7a78d9f691c6e064a61 133 Pfam PF00293 NUDIX domain 5 109 8.2E-22 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CU254_RS03900 337ec4ebe648b7a78d9f691c6e064a61 133 PRINTS PR00502 NUDIX hydrolase family signature 47 62 4.7E-9 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CU254_RS03900 337ec4ebe648b7a78d9f691c6e064a61 133 PRINTS PR00502 NUDIX hydrolase family signature 33 47 4.7E-9 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CU254_RS03900 337ec4ebe648b7a78d9f691c6e064a61 133 Gene3D G3DSA:3.90.79.10 2 131 5.4E-30 T 28-03-2018 CU254_RS03900 337ec4ebe648b7a78d9f691c6e064a61 133 ProSitePatterns PS00893 Nudix box signature. 38 59 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CU254_RS30510 29423161acc61c713717ba6894771347 360 Gene3D G3DSA:3.30.420.40 46 174 3.0E-28 T 28-03-2018 CU254_RS30510 29423161acc61c713717ba6894771347 360 SUPERFAMILY SSF46785 2 44 7.8E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS30510 29423161acc61c713717ba6894771347 360 Gene3D G3DSA:3.30.420.40 175 359 1.4E-48 T 28-03-2018 CU254_RS30510 29423161acc61c713717ba6894771347 360 SUPERFAMILY SSF53067 51 351 1.53E-56 T 28-03-2018 CU254_RS30510 29423161acc61c713717ba6894771347 360 Pfam PF00480 ROK family 55 348 1.6E-53 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CU254_RS30510 29423161acc61c713717ba6894771347 360 Gene3D G3DSA:1.10.10.10 1 45 5.9E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS11880 0354bb69cd56d39319e3fac4a063f110 520 SUPERFAMILY SSF109604 26 176 2.71E-47 T 28-03-2018 CU254_RS11880 0354bb69cd56d39319e3fac4a063f110 520 SUPERFAMILY SSF109604 228 271 2.71E-47 T 28-03-2018 CU254_RS11880 0354bb69cd56d39319e3fac4a063f110 520 Gene3D G3DSA:1.10.3210.10 8 237 2.0E-44 T 28-03-2018 CU254_RS11880 0354bb69cd56d39319e3fac4a063f110 520 SMART SM00471 58 260 1.9E-12 T 28-03-2018 IPR003607 HD/PDEase domain CU254_RS11880 0354bb69cd56d39319e3fac4a063f110 520 Gene3D G3DSA:1.10.3410.10 239 369 7.9E-12 T 28-03-2018 IPR023293 Deoxyguanosinetriphosphate triphosphohydrolase, central domain CU254_RS11880 0354bb69cd56d39319e3fac4a063f110 520 Pfam PF01966 HD domain 62 141 2.9E-11 T 28-03-2018 IPR006674 HD domain CU254_RS11880 0354bb69cd56d39319e3fac4a063f110 520 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 26 506 2.2E-60 T 28-03-2018 IPR006261 dNTP triphosphohydrolase GO:0016793 CU254_RS28755 be66afb7ddcbadad5421c9c5adcb4420 597 Gene3D G3DSA:2.60.40.740 449 594 2.4E-4 T 28-03-2018 CU254_RS28755 be66afb7ddcbadad5421c9c5adcb4420 597 Gene3D G3DSA:2.60.40.1280 364 444 0.0051 T 28-03-2018 IPR011252 Fibrogen-binding domain 1 GO:0005618|GO:0007155 CU254_RS07975 e2cde6b76dc15d63dbe291045f17c3b3 171 Gene3D G3DSA:2.30.30.240 94 162 2.8E-20 T 28-03-2018 CU254_RS07975 e2cde6b76dc15d63dbe291045f17c3b3 171 Pfam PF01782 RimM N-terminal domain 4 87 5.7E-22 T 28-03-2018 IPR002676 RimM protein GO:0006364 CU254_RS07975 e2cde6b76dc15d63dbe291045f17c3b3 171 Pfam PF05239 PRC-barrel domain 95 168 9.6E-9 T 28-03-2018 IPR027275 PRC-barrel domain CU254_RS07975 e2cde6b76dc15d63dbe291045f17c3b3 171 SUPERFAMILY SSF50447 3 91 8.95E-19 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CU254_RS07975 e2cde6b76dc15d63dbe291045f17c3b3 171 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 2 167 23.027 T 28-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 CU254_RS07975 e2cde6b76dc15d63dbe291045f17c3b3 171 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 3 167 1.9E-38 T 28-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 CU254_RS07975 e2cde6b76dc15d63dbe291045f17c3b3 171 Gene3D G3DSA:2.40.30.60 2 92 3.2E-26 T 28-03-2018 IPR002676 RimM protein GO:0006364 CU254_RS07975 e2cde6b76dc15d63dbe291045f17c3b3 171 SUPERFAMILY SSF50346 98 167 2.54E-15 T 28-03-2018 IPR011033 PRC-barrel-like CU254_RS25545 c480f418923f426849b24068d315db9b 307 SUPERFAMILY SSF54593 139 284 8.39E-28 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS25545 c480f418923f426849b24068d315db9b 307 Gene3D G3DSA:3.10.180.10 133 287 3.9E-23 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS25545 c480f418923f426849b24068d315db9b 307 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 144 254 7.8E-11 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CU254_RS25545 c480f418923f426849b24068d315db9b 307 SUPERFAMILY SSF54593 3 99 2.17E-9 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS25545 c480f418923f426849b24068d315db9b 307 Gene3D G3DSA:3.10.180.10 1 118 1.0E-6 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS11325 9b2f216431c2e893584cbf859bc7b823 887 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 887 164.923 T 28-03-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 CU254_RS11325 9b2f216431c2e893584cbf859bc7b823 887 SUPERFAMILY SSF55681 2 248 9.44E-87 T 28-03-2018 CU254_RS11325 9b2f216431c2e893584cbf859bc7b823 887 SUPERFAMILY SSF55186 560 720 3.53E-41 T 28-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 CU254_RS11325 9b2f216431c2e893584cbf859bc7b823 887 Pfam PF01411 tRNA synthetases class II (A) 5 563 3.0E-195 T 28-03-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 CU254_RS11325 9b2f216431c2e893584cbf859bc7b823 887 Pfam PF02272 DHHA1 domain 744 882 4.1E-21 T 28-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CU254_RS11325 9b2f216431c2e893584cbf859bc7b823 887 Gene3D G3DSA:3.30.930.10 1 245 4.2E-96 T 28-03-2018 CU254_RS11325 9b2f216431c2e893584cbf859bc7b823 887 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 5 865 3.3E-255 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CU254_RS11325 9b2f216431c2e893584cbf859bc7b823 887 PRINTS PR00980 Alanyl-tRNA synthetase signature 69 80 3.2E-26 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CU254_RS11325 9b2f216431c2e893584cbf859bc7b823 887 PRINTS PR00980 Alanyl-tRNA synthetase signature 279 295 3.2E-26 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CU254_RS11325 9b2f216431c2e893584cbf859bc7b823 887 PRINTS PR00980 Alanyl-tRNA synthetase signature 303 316 3.2E-26 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CU254_RS11325 9b2f216431c2e893584cbf859bc7b823 887 PRINTS PR00980 Alanyl-tRNA synthetase signature 196 207 3.2E-26 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CU254_RS11325 9b2f216431c2e893584cbf859bc7b823 887 PRINTS PR00980 Alanyl-tRNA synthetase signature 229 242 3.2E-26 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CU254_RS11325 9b2f216431c2e893584cbf859bc7b823 887 Gene3D G3DSA:3.30.980.10 561 721 1.0E-38 T 28-03-2018 CU254_RS11325 9b2f216431c2e893584cbf859bc7b823 887 SMART SM00863 661 704 8.4E-16 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CU254_RS11325 9b2f216431c2e893584cbf859bc7b823 887 SUPERFAMILY SSF101353 249 467 1.31E-57 T 28-03-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 CU254_RS11325 9b2f216431c2e893584cbf859bc7b823 887 SUPERFAMILY SSF50447 460 558 8.47E-18 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CU254_RS11325 9b2f216431c2e893584cbf859bc7b823 887 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 661 704 5.4E-13 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CU254_RS17445 d2eddb44ca9b3d0641a10d7ce75ff837 613 Pfam PF01436 NHL repeat 440 467 1.9E-6 T 28-03-2018 IPR001258 NHL repeat GO:0005515 CU254_RS17445 d2eddb44ca9b3d0641a10d7ce75ff837 613 Pfam PF01436 NHL repeat 197 223 1.3E-6 T 28-03-2018 IPR001258 NHL repeat GO:0005515 CU254_RS17445 d2eddb44ca9b3d0641a10d7ce75ff837 613 Pfam PF01436 NHL repeat 343 369 3.1E-7 T 28-03-2018 IPR001258 NHL repeat GO:0005515 CU254_RS17445 d2eddb44ca9b3d0641a10d7ce75ff837 613 Pfam PF01436 NHL repeat 243 270 2.2E-7 T 28-03-2018 IPR001258 NHL repeat GO:0005515 CU254_RS17445 d2eddb44ca9b3d0641a10d7ce75ff837 613 Pfam PF01436 NHL repeat 291 317 1.4E-4 T 28-03-2018 IPR001258 NHL repeat GO:0005515 CU254_RS17445 d2eddb44ca9b3d0641a10d7ce75ff837 613 SUPERFAMILY SSF101898 342 610 6.8E-34 T 28-03-2018 CU254_RS17445 d2eddb44ca9b3d0641a10d7ce75ff837 613 SUPERFAMILY SSF101898 138 382 1.02E-38 T 28-03-2018 CU254_RS17445 d2eddb44ca9b3d0641a10d7ce75ff837 613 Gene3D G3DSA:2.120.10.30 187 282 5.1E-20 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CU254_RS17445 d2eddb44ca9b3d0641a10d7ce75ff837 613 Gene3D G3DSA:2.120.10.30 481 612 2.1E-10 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CU254_RS17445 d2eddb44ca9b3d0641a10d7ce75ff837 613 Gene3D G3DSA:2.120.10.30 70 186 3.9E-10 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CU254_RS17445 d2eddb44ca9b3d0641a10d7ce75ff837 613 Gene3D G3DSA:2.120.10.30 389 480 1.2E-16 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CU254_RS17445 d2eddb44ca9b3d0641a10d7ce75ff837 613 Gene3D G3DSA:2.120.10.30 283 382 1.1E-16 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CU254_RS24565 b13af19381958668423e0a2528b8fcfc 237 Pfam PF12867 DinB superfamily 80 224 3.3E-11 T 28-03-2018 IPR024775 DinB-like domain CU254_RS24565 b13af19381958668423e0a2528b8fcfc 237 Gene3D G3DSA:3.30.1120.50 6 50 0.0022 T 28-03-2018 CU254_RS24565 b13af19381958668423e0a2528b8fcfc 237 SUPERFAMILY SSF109854 100 222 2.29E-11 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CU254_RS24565 b13af19381958668423e0a2528b8fcfc 237 Gene3D G3DSA:1.20.120.450 51 225 1.1E-17 T 28-03-2018 CU254_RS02900 1f3e1b35844e420f918848fc4139f0f3 335 Gene3D G3DSA:3.90.180.10 1 163 1.3E-58 T 28-03-2018 CU254_RS02900 1f3e1b35844e420f918848fc4139f0f3 335 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 58 72 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CU254_RS02900 1f3e1b35844e420f918848fc4139f0f3 335 Pfam PF00107 Zinc-binding dehydrogenase 173 291 1.8E-14 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CU254_RS02900 1f3e1b35844e420f918848fc4139f0f3 335 SMART SM00829 7 327 5.5E-6 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CU254_RS02900 1f3e1b35844e420f918848fc4139f0f3 335 Gene3D G3DSA:3.40.50.720 164 278 4.8E-25 T 28-03-2018 CU254_RS02900 1f3e1b35844e420f918848fc4139f0f3 335 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 131 8.1E-34 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CU254_RS02900 1f3e1b35844e420f918848fc4139f0f3 335 SUPERFAMILY SSF50129 1 140 3.96E-57 T 28-03-2018 IPR011032 GroES-like CU254_RS02900 1f3e1b35844e420f918848fc4139f0f3 335 SUPERFAMILY SSF50129 300 327 3.96E-57 T 28-03-2018 IPR011032 GroES-like CU254_RS02900 1f3e1b35844e420f918848fc4139f0f3 335 SUPERFAMILY SSF51735 136 319 5.05E-30 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS10200 323ab54157c2ee6bc9fe02936e830f32 380 Gene3D G3DSA:3.40.50.10540 1 380 6.9E-118 T 28-03-2018 IPR023606 CoA-transferase family III domain CU254_RS10200 323ab54157c2ee6bc9fe02936e830f32 380 Pfam PF02515 CoA-transferase family III 6 349 1.1E-79 T 28-03-2018 IPR003673 CoA-transferase family III GO:0003824 CU254_RS10200 323ab54157c2ee6bc9fe02936e830f32 380 SUPERFAMILY SSF89796 4 379 4.06E-117 T 28-03-2018 IPR023606 CoA-transferase family III domain CU254_RS07845 95aac9be81ade08b3032de32eae13325 158 Gene3D G3DSA:1.10.10.10 106 158 7.8E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS07845 95aac9be81ade08b3032de32eae13325 158 SUPERFAMILY SSF89957 5 79 3.53E-7 T 28-03-2018 IPR029756 MTH1187/YkoF-like CU254_RS07845 95aac9be81ade08b3032de32eae13325 158 Pfam PF13309 HTH domain 93 154 1.1E-19 T 28-03-2018 CU254_RS07845 95aac9be81ade08b3032de32eae13325 158 Gene3D G3DSA:3.30.70.930 1 105 3.2E-10 T 28-03-2018 IPR029756 MTH1187/YkoF-like CU254_RS04445 16a46cea655a570d85bd47c4d5779da0 573 Pfam PF02540 NAD synthase 297 544 5.0E-68 T 28-03-2018 IPR022310 NAD/GMP synthase CU254_RS04445 16a46cea655a570d85bd47c4d5779da0 573 TIGRFAM TIGR00552 nadE: NAD+ synthetase 304 550 3.5E-54 T 28-03-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 CU254_RS04445 16a46cea655a570d85bd47c4d5779da0 573 SUPERFAMILY SSF56317 1 249 3.01E-60 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CU254_RS04445 16a46cea655a570d85bd47c4d5779da0 573 Gene3D G3DSA:3.40.50.620 294 573 8.8E-66 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS04445 16a46cea655a570d85bd47c4d5779da0 573 Pfam PF00795 Carbon-nitrogen hydrolase 5 254 2.3E-30 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CU254_RS04445 16a46cea655a570d85bd47c4d5779da0 573 PIRSF PIRSF006630 1 572 4.3E-199 T 28-03-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 CU254_RS04445 16a46cea655a570d85bd47c4d5779da0 573 Gene3D G3DSA:3.60.110.10 1 256 1.0E-62 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CU254_RS04445 16a46cea655a570d85bd47c4d5779da0 573 SUPERFAMILY SSF52402 289 552 3.72E-73 T 28-03-2018 CU254_RS04145 c37def0f7b52fb36988b794fafd98130 334 Pfam PF01944 Stage II sporulation protein M 107 282 2.8E-35 T 28-03-2018 IPR002798 Stage II sporulation protein M-like CU254_RS05310 931684e192e8c5cf82f41662d217704f 142 Gene3D G3DSA:1.10.10.10 1 135 2.9E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS05310 931684e192e8c5cf82f41662d217704f 142 Pfam PF12802 MarR family 20 80 1.1E-12 T 28-03-2018 CU254_RS05310 931684e192e8c5cf82f41662d217704f 142 SMART SM00347 14 117 3.3E-18 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS05310 931684e192e8c5cf82f41662d217704f 142 SUPERFAMILY SSF46785 2 132 7.13E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS05310 931684e192e8c5cf82f41662d217704f 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 76 92 3.0E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS05310 931684e192e8c5cf82f41662d217704f 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 40 56 3.0E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS05310 931684e192e8c5cf82f41662d217704f 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 57 72 3.0E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS05310 931684e192e8c5cf82f41662d217704f 142 PRINTS PR00598 Bacterial regulatory protein MarR family signature 107 127 3.0E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS22860 eacd551af00bca730e96dc2b6f2baf22 242 SUPERFAMILY SSF52540 16 165 7.85E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS22860 eacd551af00bca730e96dc2b6f2baf22 242 Gene3D G3DSA:3.40.50.300 10 189 1.3E-13 T 28-03-2018 CU254_RS09770 d5ac8cbcb16fe5ff687daea18e1e2f14 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 1.5E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS09770 d5ac8cbcb16fe5ff687daea18e1e2f14 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 1.5E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS09770 d5ac8cbcb16fe5ff687daea18e1e2f14 204 Gene3D G3DSA:1.10.357.10 67 202 1.8E-12 T 28-03-2018 CU254_RS09770 d5ac8cbcb16fe5ff687daea18e1e2f14 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 69 3.1E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS09770 d5ac8cbcb16fe5ff687daea18e1e2f14 204 SUPERFAMILY SSF48498 81 197 2.67E-9 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS09770 d5ac8cbcb16fe5ff687daea18e1e2f14 204 Gene3D G3DSA:1.10.10.60 1 66 1.9E-18 T 28-03-2018 CU254_RS09770 d5ac8cbcb16fe5ff687daea18e1e2f14 204 SUPERFAMILY SSF46689 12 77 2.82E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS09770 d5ac8cbcb16fe5ff687daea18e1e2f14 204 Pfam PF16859 Bacterial transcriptional repressor C-terminal 80 192 1.1E-18 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS30270 ed92336886e01a494c55309cbeb1c304 397 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 9 371 1.0E-118 T 28-03-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 CU254_RS30270 ed92336886e01a494c55309cbeb1c304 397 SUPERFAMILY SSF53756 9 378 8.52E-108 T 28-03-2018 CU254_RS30270 ed92336886e01a494c55309cbeb1c304 397 Gene3D G3DSA:3.40.50.2000 8 212 1.2E-60 T 28-03-2018 CU254_RS30270 ed92336886e01a494c55309cbeb1c304 397 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 28 371 5.0E-99 T 28-03-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001 CU254_RS30270 ed92336886e01a494c55309cbeb1c304 397 Gene3D G3DSA:3.40.50.2000 213 355 4.1E-36 T 28-03-2018 CU254_RS04975 a99ed545830fe83017b95360b03a9d4d 215 SMART SM00448 2 115 5.3E-32 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS04975 a99ed545830fe83017b95360b03a9d4d 215 Gene3D G3DSA:3.40.50.2300 1 133 2.8E-40 T 28-03-2018 CU254_RS04975 a99ed545830fe83017b95360b03a9d4d 215 SMART SM00421 152 209 1.1E-23 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS04975 a99ed545830fe83017b95360b03a9d4d 215 SUPERFAMILY SSF52172 2 133 7.83E-36 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS04975 a99ed545830fe83017b95360b03a9d4d 215 Gene3D G3DSA:1.10.10.10 134 214 2.6E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS04975 a99ed545830fe83017b95360b03a9d4d 215 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 208 5.7E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS04975 a99ed545830fe83017b95360b03a9d4d 215 SUPERFAMILY SSF46894 143 215 1.02E-20 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS04975 a99ed545830fe83017b95360b03a9d4d 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 2.8E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS04975 a99ed545830fe83017b95360b03a9d4d 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 2.8E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS04975 a99ed545830fe83017b95360b03a9d4d 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 2.8E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS04975 a99ed545830fe83017b95360b03a9d4d 215 Pfam PF00072 Response regulator receiver domain 4 113 9.8E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS27775 15458331ffb1ba33dbc5080cf98e30ad 162 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 43 92 1.7E-19 T 28-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CU254_RS27775 15458331ffb1ba33dbc5080cf98e30ad 162 Gene3D G3DSA:1.20.1290.10 11 158 3.8E-31 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CU254_RS27775 15458331ffb1ba33dbc5080cf98e30ad 162 SUPERFAMILY SSF69118 12 155 3.93E-38 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CU254_RS27775 15458331ffb1ba33dbc5080cf98e30ad 162 Pfam PF02627 Carboxymuconolactone decarboxylase family 25 108 7.5E-22 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CU254_RS31475 2915e51d7b671e60301cbb7043579c75 188 SMART SM00867 18 185 4.0E-66 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CU254_RS31475 2915e51d7b671e60301cbb7043579c75 188 Pfam PF04264 YceI-like domain 19 184 3.5E-42 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CU254_RS31475 2915e51d7b671e60301cbb7043579c75 188 SUPERFAMILY SSF101874 17 187 1.57E-54 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CU254_RS31475 2915e51d7b671e60301cbb7043579c75 188 Gene3D G3DSA:2.40.128.110 14 188 8.5E-55 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CU254_RS23770 07a8be95700eb71c623f99ff45c689d0 453 PIRSF PIRSF000521 5 148 3.8E-6 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CU254_RS23770 07a8be95700eb71c623f99ff45c689d0 453 PIRSF PIRSF000521 121 450 4.4E-27 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CU254_RS23770 07a8be95700eb71c623f99ff45c689d0 453 Pfam PF00202 Aminotransferase class-III 45 443 2.7E-76 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CU254_RS23770 07a8be95700eb71c623f99ff45c689d0 453 Gene3D G3DSA:3.90.1150.10 331 453 2.6E-32 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS23770 07a8be95700eb71c623f99ff45c689d0 453 Gene3D G3DSA:3.40.640.10 72 330 4.6E-61 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS23770 07a8be95700eb71c623f99ff45c689d0 453 SUPERFAMILY SSF53383 22 446 1.99E-98 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS34820 bff4b166d17873beba3ef43827ad3bd7 313 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 249 262 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CU254_RS34820 bff4b166d17873beba3ef43827ad3bd7 313 Pfam PF00294 pfkB family carbohydrate kinase 28 303 2.6E-40 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CU254_RS34820 bff4b166d17873beba3ef43827ad3bd7 313 Gene3D G3DSA:3.40.1190.20 1 313 1.3E-51 T 28-03-2018 IPR029056 Ribokinase-like CU254_RS34820 bff4b166d17873beba3ef43827ad3bd7 313 SUPERFAMILY SSF53613 2 304 2.49E-57 T 28-03-2018 IPR029056 Ribokinase-like CU254_RS13275 02fc5919ea8401ac0983a955e7fe8704 509 Pfam PF00005 ABC transporter 25 174 1.0E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS13275 02fc5919ea8401ac0983a955e7fe8704 509 Pfam PF00005 ABC transporter 281 436 6.1E-17 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS13275 02fc5919ea8401ac0983a955e7fe8704 509 ProSitePatterns PS00211 ABC transporters family signature. 409 423 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS13275 02fc5919ea8401ac0983a955e7fe8704 509 SUPERFAMILY SSF52540 8 234 2.92E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS13275 02fc5919ea8401ac0983a955e7fe8704 509 SUPERFAMILY SSF52540 263 494 1.87E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS13275 02fc5919ea8401ac0983a955e7fe8704 509 Gene3D G3DSA:3.40.50.300 260 499 1.5E-33 T 28-03-2018 CU254_RS13275 02fc5919ea8401ac0983a955e7fe8704 509 Gene3D G3DSA:3.40.50.300 6 243 1.0E-54 T 28-03-2018 CU254_RS13275 02fc5919ea8401ac0983a955e7fe8704 509 SMART SM00382 33 222 3.1E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS13275 02fc5919ea8401ac0983a955e7fe8704 509 SMART SM00382 289 484 0.12 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS04495 9d450e164212f14f6b9053c911f6f4f7 145 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 4.0E-15 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS04495 9d450e164212f14f6b9053c911f6f4f7 145 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 4.0E-15 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS04495 9d450e164212f14f6b9053c911f6f4f7 145 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 4.0E-15 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS04495 9d450e164212f14f6b9053c911f6f4f7 145 SUPERFAMILY SSF46785 3 62 5.15E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS04495 9d450e164212f14f6b9053c911f6f4f7 145 SMART SM00344 3 109 1.9E-35 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CU254_RS04495 9d450e164212f14f6b9053c911f6f4f7 145 Gene3D G3DSA:1.10.10.10 1 52 1.3E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS04495 9d450e164212f14f6b9053c911f6f4f7 145 SUPERFAMILY SSF54909 64 138 1.47E-14 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS04495 9d450e164212f14f6b9053c911f6f4f7 145 Gene3D G3DSA:3.30.70.920 53 140 2.2E-18 T 28-03-2018 CU254_RS04495 9d450e164212f14f6b9053c911f6f4f7 145 Pfam PF01037 Lrp/AsnC ligand binding domain 69 135 1.0E-10 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CU254_RS04495 9d450e164212f14f6b9053c911f6f4f7 145 Pfam PF13404 AsnC-type helix-turn-helix domain 3 44 1.4E-16 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS01635 66344981ec70fd63c20a7cde6c5a3311 163 SUPERFAMILY SSF89963 4 88 1.1E-24 T 28-03-2018 IPR007551 Protein of unknown function DUF520 CU254_RS01635 66344981ec70fd63c20a7cde6c5a3311 163 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 3 163 24.602 T 28-03-2018 IPR007551 Protein of unknown function DUF520 CU254_RS01635 66344981ec70fd63c20a7cde6c5a3311 163 SUPERFAMILY SSF89963 92 163 4.19E-24 T 28-03-2018 IPR007551 Protein of unknown function DUF520 CU254_RS01635 66344981ec70fd63c20a7cde6c5a3311 163 Gene3D G3DSA:3.30.70.860 98 163 1.5E-29 T 28-03-2018 IPR035571 UPF0234/UPF0381 domain CU254_RS01635 66344981ec70fd63c20a7cde6c5a3311 163 Gene3D G3DSA:3.30.70.990 12 97 2.1E-27 T 28-03-2018 IPR035570 UPF0234 N-terminal domain CU254_RS01635 66344981ec70fd63c20a7cde6c5a3311 163 Pfam PF04461 Protein of unknown function (DUF520) 4 163 6.2E-59 T 28-03-2018 IPR007551 Protein of unknown function DUF520 CU254_RS39930 9a4ea48545861ce967da1f5365611ab1 263 SUPERFAMILY SSF52172 2 131 1.99E-23 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS39930 9a4ea48545861ce967da1f5365611ab1 263 Pfam PF00072 Response regulator receiver domain 2 123 1.6E-16 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS39930 9a4ea48545861ce967da1f5365611ab1 263 Pfam PF04397 LytTr DNA-binding domain 162 256 5.4E-22 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CU254_RS39930 9a4ea48545861ce967da1f5365611ab1 263 SMART SM00850 160 257 1.1E-29 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CU254_RS39930 9a4ea48545861ce967da1f5365611ab1 263 Gene3D G3DSA:3.40.50.2300 1 136 3.8E-23 T 28-03-2018 CU254_RS39930 9a4ea48545861ce967da1f5365611ab1 263 Gene3D G3DSA:2.40.50.40 150 219 4.9E-15 T 28-03-2018 CU254_RS39930 9a4ea48545861ce967da1f5365611ab1 263 SMART SM00448 1 124 6.9E-12 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS10065 0ac98fe0769e20d997efe0edb7ad8d95 151 Pfam PF13376 Bacteriocin-protection, YdeI or OmpD-Associated 89 146 5.0E-19 T 28-03-2018 CU254_RS10065 0ac98fe0769e20d997efe0edb7ad8d95 151 Pfam PF08922 Domain of unknown function (DUF1905) 8 81 1.2E-15 T 28-03-2018 IPR015018 Protein of unknown function DUF1905 CU254_RS10065 0ac98fe0769e20d997efe0edb7ad8d95 151 SUPERFAMILY SSF141694 3 83 9.94E-15 T 28-03-2018 CU254_RS10065 0ac98fe0769e20d997efe0edb7ad8d95 151 Gene3D G3DSA:2.40.30.100 3 82 1.6E-17 T 28-03-2018 IPR015018 Protein of unknown function DUF1905 CU254_RS12830 29f4beb6c239cd106d43489f353258a1 376 Gene3D G3DSA:1.10.540.10 1 119 1.6E-21 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS12830 29f4beb6c239cd106d43489f353258a1 376 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 114 1.3E-16 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS12830 29f4beb6c239cd106d43489f353258a1 376 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 226 374 1.9E-48 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS12830 29f4beb6c239cd106d43489f353258a1 376 PIRSF PIRSF016578 127 191 0.033 T 28-03-2018 CU254_RS12830 29f4beb6c239cd106d43489f353258a1 376 PIRSF PIRSF016578 236 372 4.1E-13 T 28-03-2018 CU254_RS12830 29f4beb6c239cd106d43489f353258a1 376 PIRSF PIRSF016578 36 80 110.0 T 28-03-2018 CU254_RS12830 29f4beb6c239cd106d43489f353258a1 376 SUPERFAMILY SSF56645 2 239 1.7E-65 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS12830 29f4beb6c239cd106d43489f353258a1 376 Gene3D G3DSA:2.40.110.10 120 219 4.1E-34 T 28-03-2018 CU254_RS12830 29f4beb6c239cd106d43489f353258a1 376 SUPERFAMILY SSF47203 225 375 1.34E-52 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS12830 29f4beb6c239cd106d43489f353258a1 376 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 120 213 1.1E-23 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CU254_RS12830 29f4beb6c239cd106d43489f353258a1 376 Gene3D G3DSA:1.20.140.10 220 376 2.4E-55 T 28-03-2018 CU254_RS01645 b825eafba9babb144824378b52572164 382 SUPERFAMILY SSF50939 54 318 3.34E-15 T 28-03-2018 IPR011040 Sialidases KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 CU254_RS01645 b825eafba9babb144824378b52572164 382 Gene3D G3DSA:2.120.10.10 34 374 9.7E-42 T 28-03-2018 CU254_RS33490 9ed1d375b51193548b8eba21602c0714 379 Pfam PF07730 Histidine kinase 196 257 1.5E-9 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CU254_RS33490 9ed1d375b51193548b8eba21602c0714 379 Gene3D G3DSA:3.30.565.10 261 374 2.3E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS07915 14a2bad5eef795db07707f81f3af7dff 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 28-03-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 CU254_RS07915 14a2bad5eef795db07707f81f3af7dff 112 SUPERFAMILY SSF54913 1 112 5.08E-43 T 28-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta CU254_RS07915 14a2bad5eef795db07707f81f3af7dff 112 SMART SM00938 4 105 7.4E-60 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CU254_RS07915 14a2bad5eef795db07707f81f3af7dff 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 1.5E-40 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CU254_RS07915 14a2bad5eef795db07707f81f3af7dff 112 PIRSF PIRSF039144 1 112 1.3E-52 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CU254_RS07915 14a2bad5eef795db07707f81f3af7dff 112 Gene3D G3DSA:3.30.70.120 1 109 1.8E-45 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CU254_RS07915 14a2bad5eef795db07707f81f3af7dff 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 28-03-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 CU254_RS07915 14a2bad5eef795db07707f81f3af7dff 112 PRINTS PR00340 P-II protein signature 2 17 5.5E-38 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CU254_RS07915 14a2bad5eef795db07707f81f3af7dff 112 PRINTS PR00340 P-II protein signature 52 75 5.5E-38 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CU254_RS07915 14a2bad5eef795db07707f81f3af7dff 112 PRINTS PR00340 P-II protein signature 23 41 5.5E-38 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CU254_RS07915 14a2bad5eef795db07707f81f3af7dff 112 PRINTS PR00340 P-II protein signature 83 103 5.5E-38 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CU254_RS31430 99aa3741145157827bad9ff47132229c 419 SUPERFAMILY SSF53474 44 416 5.09E-93 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS31430 99aa3741145157827bad9ff47132229c 419 PRINTS PR00412 Epoxide hydrolase signature 392 414 2.2E-14 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS31430 99aa3741145157827bad9ff47132229c 419 PRINTS PR00412 Epoxide hydrolase signature 218 231 2.2E-14 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS31430 99aa3741145157827bad9ff47132229c 419 PRINTS PR00412 Epoxide hydrolase signature 173 188 2.2E-14 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS31430 99aa3741145157827bad9ff47132229c 419 PRINTS PR00412 Epoxide hydrolase signature 144 162 2.2E-14 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS31430 99aa3741145157827bad9ff47132229c 419 Gene3D G3DSA:3.40.50.1820 36 419 2.6E-68 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS31430 99aa3741145157827bad9ff47132229c 419 Pfam PF06441 Epoxide hydrolase N terminus 50 153 1.9E-30 T 28-03-2018 IPR010497 Epoxide hydrolase, N-terminal KEGG: 00980+3.3.2.9|Reactome: R-HSA-211945 CU254_RS31430 99aa3741145157827bad9ff47132229c 419 PIRSF PIRSF001112 5 419 8.8E-119 T 28-03-2018 IPR016292 Epoxide hydrolase GO:0033961 KEGG: 00980+3.3.2.9|Reactome: R-HSA-211945 CU254_RS01020 4cc14264efdfc0f2ed5a7b51a952c94c 275 Gene3D G3DSA:1.20.5.170 113 217 7.9E-4 T 28-03-2018 CU254_RS01020 4cc14264efdfc0f2ed5a7b51a952c94c 275 Pfam PF14257 Domain of unknown function (DUF4349) 18 264 8.4E-68 T 28-03-2018 IPR025645 Domain of unknown function DUF4349 CU254_RS29340 104a9acd0e58d8acd2e998d1626cbce1 692 Gene3D G3DSA:3.30.420.40 12 335 1.6E-9 T 28-03-2018 CU254_RS29340 104a9acd0e58d8acd2e998d1626cbce1 692 Gene3D G3DSA:3.40.47.10 352 507 0.18 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS29340 104a9acd0e58d8acd2e998d1626cbce1 692 Pfam PF01968 Hydantoinase/oxoprolinase 211 509 1.1E-90 T 28-03-2018 IPR002821 Hydantoinase/oxoprolinase GO:0016787 Reactome: R-HSA-174403 CU254_RS29340 104a9acd0e58d8acd2e998d1626cbce1 692 SUPERFAMILY SSF53067 269 354 2.45E-5 T 28-03-2018 CU254_RS29340 104a9acd0e58d8acd2e998d1626cbce1 692 SUPERFAMILY SSF53067 14 87 2.45E-5 T 28-03-2018 CU254_RS29340 104a9acd0e58d8acd2e998d1626cbce1 692 SUPERFAMILY SSF53067 403 502 2.45E-5 T 28-03-2018 CU254_RS29340 104a9acd0e58d8acd2e998d1626cbce1 692 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 13 190 1.4E-49 T 28-03-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403 CU254_RS37715 6c520b6a8a02354b8f5ce3f41f460b1d 498 PIRSF PIRSF036492 31 498 3.2E-94 T 28-03-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0004030|GO:0006081|GO:0055114 CU254_RS37715 6c520b6a8a02354b8f5ce3f41f460b1d 498 Gene3D G3DSA:3.40.605.10 5 261 8.8E-81 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CU254_RS37715 6c520b6a8a02354b8f5ce3f41f460b1d 498 Pfam PF00171 Aldehyde dehydrogenase family 13 463 8.5E-130 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CU254_RS37715 6c520b6a8a02354b8f5ce3f41f460b1d 498 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 242 249 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CU254_RS37715 6c520b6a8a02354b8f5ce3f41f460b1d 498 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 270 281 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CU254_RS37715 6c520b6a8a02354b8f5ce3f41f460b1d 498 SUPERFAMILY SSF53720 12 468 2.49E-136 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CU254_RS37715 6c520b6a8a02354b8f5ce3f41f460b1d 498 Gene3D G3DSA:3.40.309.10 262 443 2.0E-59 T 28-03-2018 CU254_RS34290 af11240dd3c088d4743d4308b8d336ce 1086 SUPERFAMILY SSF52540 668 829 1.05E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS34290 af11240dd3c088d4743d4308b8d336ce 1086 SUPERFAMILY SSF52540 261 407 1.05E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS34290 af11240dd3c088d4743d4308b8d336ce 1086 Pfam PF00271 Helicase conserved C-terminal domain 706 827 1.7E-11 T 28-03-2018 IPR001650 Helicase, C-terminal CU254_RS34290 af11240dd3c088d4743d4308b8d336ce 1086 Gene3D G3DSA:3.40.50.300 247 498 1.5E-24 T 28-03-2018 CU254_RS34290 af11240dd3c088d4743d4308b8d336ce 1086 Gene3D G3DSA:3.40.50.300 671 864 3.9E-23 T 28-03-2018 CU254_RS34290 af11240dd3c088d4743d4308b8d336ce 1086 Pfam PF00176 SNF2 family N-terminal domain 236 414 4.5E-12 T 28-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 CU254_RS34290 af11240dd3c088d4743d4308b8d336ce 1086 SMART SM00487 245 430 2.8E-10 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CU254_RS34290 af11240dd3c088d4743d4308b8d336ce 1086 SMART SM00490 725 827 4.8E-8 T 28-03-2018 IPR001650 Helicase, C-terminal CU254_RS34290 af11240dd3c088d4743d4308b8d336ce 1086 Gene3D G3DSA:3.30.870.10 73 192 8.2E-4 T 28-03-2018 CU254_RS14020 682b30cc48da3689e99622ac7c835008 449 Pfam PF00155 Aminotransferase class I and II 154 393 9.4E-17 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CU254_RS14020 682b30cc48da3689e99622ac7c835008 449 SUPERFAMILY SSF46785 28 98 6.81E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS14020 682b30cc48da3689e99622ac7c835008 449 Gene3D G3DSA:3.90.1150.10 328 447 1.6E-14 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS14020 682b30cc48da3689e99622ac7c835008 449 SUPERFAMILY SSF53383 100 446 2.8E-47 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS14020 682b30cc48da3689e99622ac7c835008 449 SMART SM00345 30 89 4.9E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS14020 682b30cc48da3689e99622ac7c835008 449 Pfam PF00392 Bacterial regulatory proteins, gntR family 28 89 1.8E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS14020 682b30cc48da3689e99622ac7c835008 449 Gene3D G3DSA:1.10.10.10 22 97 4.0E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS14020 682b30cc48da3689e99622ac7c835008 449 Gene3D G3DSA:3.40.640.10 103 327 1.2E-22 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS30650 a9091a6304ecd3dfad1d7fce5679f13f 153 Gene3D G3DSA:1.10.10.10 9 137 7.3E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS30650 a9091a6304ecd3dfad1d7fce5679f13f 153 SMART SM00347 26 127 1.9E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS30650 a9091a6304ecd3dfad1d7fce5679f13f 153 Pfam PF12802 MarR family 38 91 5.4E-10 T 28-03-2018 CU254_RS30650 a9091a6304ecd3dfad1d7fce5679f13f 153 SUPERFAMILY SSF46785 22 137 4.33E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS39805 9ebc012526459508d7964b69d84f8a24 435 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 313 409 4.6E-26 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CU254_RS39805 9ebc012526459508d7964b69d84f8a24 435 SUPERFAMILY SSF52413 301 417 4.05E-32 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CU254_RS39805 9ebc012526459508d7964b69d84f8a24 435 SMART SM00984 312 409 4.1E-35 T 28-03-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CU254_RS39805 9ebc012526459508d7964b69d84f8a24 435 PIRSF PIRSF000124 4 424 1.1E-122 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CU254_RS39805 9ebc012526459508d7964b69d84f8a24 435 SUPERFAMILY SSF51735 5 188 2.07E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS39805 9ebc012526459508d7964b69d84f8a24 435 Gene3D G3DSA:3.40.50.720 227 434 8.8E-65 T 28-03-2018 CU254_RS39805 9ebc012526459508d7964b69d84f8a24 435 Gene3D G3DSA:1.20.5.100 199 224 1.9E-12 T 28-03-2018 CU254_RS39805 9ebc012526459508d7964b69d84f8a24 435 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 5 177 2.2E-55 T 28-03-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CU254_RS39805 9ebc012526459508d7964b69d84f8a24 435 SUPERFAMILY SSF48179 197 293 6.97E-29 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CU254_RS39805 9ebc012526459508d7964b69d84f8a24 435 PIRSF PIRSF500134 4 427 6.3E-150 T 28-03-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 CU254_RS39805 9ebc012526459508d7964b69d84f8a24 435 Gene3D G3DSA:3.40.50.720 3 198 1.5E-51 T 28-03-2018 CU254_RS39805 9ebc012526459508d7964b69d84f8a24 435 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 197 287 1.5E-33 T 28-03-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CU254_RS39805 9ebc012526459508d7964b69d84f8a24 435 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 5 405 4.5E-129 T 28-03-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CU254_RS29785 b35a5c08a9f6dc04decad85563ee9a94 542 Pfam PF02954 Bacterial regulatory protein, Fis family 494 532 3.2E-13 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CU254_RS29785 b35a5c08a9f6dc04decad85563ee9a94 542 Gene3D G3DSA:1.10.10.60 494 535 8.0E-13 T 28-03-2018 CU254_RS29785 b35a5c08a9f6dc04decad85563ee9a94 542 Gene3D G3DSA:3.40.50.300 286 405 4.5E-6 T 28-03-2018 CU254_RS29785 b35a5c08a9f6dc04decad85563ee9a94 542 SUPERFAMILY SSF46689 494 534 1.21E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS29785 b35a5c08a9f6dc04decad85563ee9a94 542 SUPERFAMILY SSF52540 291 479 2.92E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS29785 b35a5c08a9f6dc04decad85563ee9a94 542 Gene3D G3DSA:1.10.8.60 411 486 1.9E-11 T 28-03-2018 CU254_RS29785 b35a5c08a9f6dc04decad85563ee9a94 542 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 499 516 7.0E-10 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CU254_RS29785 b35a5c08a9f6dc04decad85563ee9a94 542 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 516 536 7.0E-10 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CU254_RS26550 a969bc9c28c875dea0246e9ff3843e96 332 TIGRFAM TIGR03842 F420_CPS_4043: F420-dependent oxidoreductase, CPS_4043 family 2 330 5.8E-174 T 28-03-2018 IPR022315 F420-dependent oxidoreductase-predicted, CPS4043 CU254_RS26550 a969bc9c28c875dea0246e9ff3843e96 332 Pfam PF00296 Luciferase-like monooxygenase 1 305 4.9E-51 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS26550 a969bc9c28c875dea0246e9ff3843e96 332 Gene3D G3DSA:3.20.20.30 1 332 6.2E-62 T 28-03-2018 CU254_RS26550 a969bc9c28c875dea0246e9ff3843e96 332 SUPERFAMILY SSF51679 1 328 1.44E-56 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS12925 b298b33dafa4fe78ca17228a8e8f2778 198 SUPERFAMILY SSF46689 6 81 1.05E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS12925 b298b33dafa4fe78ca17228a8e8f2778 198 SUPERFAMILY SSF48498 91 186 7.12E-6 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS12925 b298b33dafa4fe78ca17228a8e8f2778 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 59 2.2E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS12925 b298b33dafa4fe78ca17228a8e8f2778 198 Gene3D G3DSA:1.10.10.60 8 60 1.4E-16 T 28-03-2018 CU254_RS12925 b298b33dafa4fe78ca17228a8e8f2778 198 Gene3D G3DSA:1.10.357.10 61 197 4.1E-16 T 28-03-2018 CU254_RS13210 9e6b4743602a4dd07a32b063fd7454c4 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 155 183 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS13210 9e6b4743602a4dd07a32b063fd7454c4 245 SUPERFAMILY SSF51735 4 245 3.86E-59 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS13210 9e6b4743602a4dd07a32b063fd7454c4 245 Gene3D G3DSA:3.40.50.720 1 210 6.4E-60 T 28-03-2018 CU254_RS13210 9e6b4743602a4dd07a32b063fd7454c4 245 Pfam PF00106 short chain dehydrogenase 5 212 3.5E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS13210 9e6b4743602a4dd07a32b063fd7454c4 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.6E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS13210 9e6b4743602a4dd07a32b063fd7454c4 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 168 187 1.6E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS13210 9e6b4743602a4dd07a32b063fd7454c4 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 1.6E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS13210 9e6b4743602a4dd07a32b063fd7454c4 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 187 3.6E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS13210 9e6b4743602a4dd07a32b063fd7454c4 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 3.6E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS13210 9e6b4743602a4dd07a32b063fd7454c4 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 3.6E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS13210 9e6b4743602a4dd07a32b063fd7454c4 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 189 206 3.6E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS13210 9e6b4743602a4dd07a32b063fd7454c4 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 3.6E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS16230 52812704d4d11c18ac877a281496d3b6 248 Pfam PF03861 ANTAR domain 181 234 9.5E-17 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 CU254_RS16230 52812704d4d11c18ac877a281496d3b6 248 SMART SM00065 33 177 5.1E-7 T 28-03-2018 IPR003018 GAF domain GO:0005515 CU254_RS16230 52812704d4d11c18ac877a281496d3b6 248 PIRSF PIRSF036625 3 243 5.8E-49 T 28-03-2018 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative CU254_RS16230 52812704d4d11c18ac877a281496d3b6 248 Gene3D G3DSA:1.10.10.10 194 235 2.6E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS16230 52812704d4d11c18ac877a281496d3b6 248 Pfam PF13185 GAF domain 33 167 3.6E-12 T 28-03-2018 IPR003018 GAF domain GO:0005515 CU254_RS16230 52812704d4d11c18ac877a281496d3b6 248 SMART SM01012 179 234 2.3E-18 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 CU254_RS16230 52812704d4d11c18ac877a281496d3b6 248 SUPERFAMILY SSF52172 170 234 3.63E-6 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS16230 52812704d4d11c18ac877a281496d3b6 248 Gene3D G3DSA:3.30.450.40 11 193 7.6E-27 T 28-03-2018 IPR029016 GAF domain-like CU254_RS16230 52812704d4d11c18ac877a281496d3b6 248 SUPERFAMILY SSF55781 14 171 6.11E-18 T 28-03-2018 IPR029016 GAF domain-like CU254_RS17620 784d36f40c137572592a581ad6d75753 187 Gene3D G3DSA:1.10.10.60 2 54 7.5E-10 T 28-03-2018 CU254_RS17620 784d36f40c137572592a581ad6d75753 187 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 56 1.4E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS17620 784d36f40c137572592a581ad6d75753 187 Gene3D G3DSA:1.10.357.10 55 184 1.4E-7 T 28-03-2018 CU254_RS17620 784d36f40c137572592a581ad6d75753 187 SUPERFAMILY SSF46689 6 73 3.04E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS13770 b51182316a5439324c2c4cb9126e75f6 258 SMART SM00345 18 75 7.3E-4 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS13770 b51182316a5439324c2c4cb9126e75f6 258 Pfam PF07702 UTRA domain 105 234 1.7E-29 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CU254_RS13770 b51182316a5439324c2c4cb9126e75f6 258 SMART SM00866 97 235 1.5E-25 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CU254_RS13770 b51182316a5439324c2c4cb9126e75f6 258 Gene3D G3DSA:1.10.10.10 2 75 6.5E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS13770 b51182316a5439324c2c4cb9126e75f6 258 SUPERFAMILY SSF64288 84 240 3.61E-31 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CU254_RS13770 b51182316a5439324c2c4cb9126e75f6 258 Gene3D G3DSA:3.40.1410.10 76 243 2.4E-32 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CU254_RS13770 b51182316a5439324c2c4cb9126e75f6 258 Pfam PF00392 Bacterial regulatory proteins, gntR family 16 71 4.3E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS13770 b51182316a5439324c2c4cb9126e75f6 258 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 35 49 1.6E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS13770 b51182316a5439324c2c4cb9126e75f6 258 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 65 1.6E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS13770 b51182316a5439324c2c4cb9126e75f6 258 SUPERFAMILY SSF46785 9 79 2.52E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS03455 917c04e315dde3d41245e38ff80b97fe 302 Gene3D G3DSA:3.40.50.1820 24 294 3.4E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS03455 917c04e315dde3d41245e38ff80b97fe 302 SUPERFAMILY SSF53474 62 274 7.95E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS03455 917c04e315dde3d41245e38ff80b97fe 302 Pfam PF01674 Lipase (class 2) 65 238 4.2E-12 T 28-03-2018 IPR002918 Lipase EstA/Esterase EstB GO:0016787 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 CU254_RS30785 43025f457d3c4b9485da2a9b5977637d 150 Gene3D G3DSA:3.40.930.10 1 149 7.9E-34 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CU254_RS30785 43025f457d3c4b9485da2a9b5977637d 150 SUPERFAMILY SSF55804 1 147 2.22E-34 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CU254_RS30785 43025f457d3c4b9485da2a9b5977637d 150 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 7 132 6.0E-34 T 28-03-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 CU254_RS30785 43025f457d3c4b9485da2a9b5977637d 150 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 6 147 2.6E-31 T 28-03-2018 IPR002178 PTS EIIA type-2 domain CU254_RS20270 5b746b320808dfe088b5139d40a9b9a2 298 PRINTS PR00111 Alpha/beta hydrolase fold signature 134 147 1.9E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS20270 5b746b320808dfe088b5139d40a9b9a2 298 PRINTS PR00111 Alpha/beta hydrolase fold signature 74 89 1.9E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS20270 5b746b320808dfe088b5139d40a9b9a2 298 PRINTS PR00111 Alpha/beta hydrolase fold signature 233 247 1.9E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS20270 5b746b320808dfe088b5139d40a9b9a2 298 PRINTS PR00111 Alpha/beta hydrolase fold signature 120 133 1.9E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS20270 5b746b320808dfe088b5139d40a9b9a2 298 SUPERFAMILY SSF53474 30 263 8.31E-43 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS20270 5b746b320808dfe088b5139d40a9b9a2 298 Gene3D G3DSA:3.40.50.1820 18 289 6.0E-35 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS20270 5b746b320808dfe088b5139d40a9b9a2 298 Pfam PF00561 alpha/beta hydrolase fold 49 260 3.4E-16 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS18905 8dc8e3b86844c9389934b2af5f1b0d09 191 Pfam PF13305 WHG domain 90 167 3.4E-18 T 28-03-2018 IPR025996 WHG domain CU254_RS18905 8dc8e3b86844c9389934b2af5f1b0d09 191 SUPERFAMILY SSF48498 86 168 8.16E-17 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS18905 8dc8e3b86844c9389934b2af5f1b0d09 191 Gene3D G3DSA:1.10.357.10 59 188 2.8E-19 T 28-03-2018 CU254_RS18905 8dc8e3b86844c9389934b2af5f1b0d09 191 SUPERFAMILY SSF46689 9 74 4.63E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS18905 8dc8e3b86844c9389934b2af5f1b0d09 191 Gene3D G3DSA:1.10.10.60 9 58 2.4E-12 T 28-03-2018 CU254_RS18905 8dc8e3b86844c9389934b2af5f1b0d09 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 58 1.8E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS35520 0d880e89db97b2fef3422444b1d5d16b 221 SUPERFAMILY SSF51391 9 218 1.18E-59 T 28-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CU254_RS35520 0d880e89db97b2fef3422444b1d5d16b 221 Gene3D G3DSA:3.20.20.70 7 221 4.4E-46 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS35520 0d880e89db97b2fef3422444b1d5d16b 221 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 15 221 25.314 T 28-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CU254_RS35520 0d880e89db97b2fef3422444b1d5d16b 221 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 17 216 3.6E-61 T 28-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CU254_RS35520 0d880e89db97b2fef3422444b1d5d16b 221 Pfam PF02581 Thiamine monophosphate synthase 18 203 7.3E-52 T 28-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CU254_RS02455 3ac8315327fdf2b864eb0c5b0463fc07 487 Pfam PF08031 Berberine and berberine like 445 486 1.6E-14 T 28-03-2018 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 CU254_RS02455 3ac8315327fdf2b864eb0c5b0463fc07 487 SUPERFAMILY SSF56176 67 256 5.06E-48 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CU254_RS02455 3ac8315327fdf2b864eb0c5b0463fc07 487 Gene3D G3DSA:3.30.43.10 59 141 3.0E-15 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CU254_RS02455 3ac8315327fdf2b864eb0c5b0463fc07 487 Pfam PF01565 FAD binding domain 94 226 3.1E-28 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CU254_RS02455 3ac8315327fdf2b864eb0c5b0463fc07 487 Gene3D G3DSA:3.30.465.10 147 284 3.5E-38 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CU254_RS17715 18696fe56f5ee58aec102d145563ffc8 547 Gene3D G3DSA:3.40.190.10 173 314 6.2E-26 T 28-03-2018 CU254_RS17715 18696fe56f5ee58aec102d145563ffc8 547 SUPERFAMILY SSF53850 46 544 4.13E-108 T 28-03-2018 CU254_RS17715 18696fe56f5ee58aec102d145563ffc8 547 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 94 464 2.4E-70 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CU254_RS17715 18696fe56f5ee58aec102d145563ffc8 547 Gene3D G3DSA:3.10.105.10 315 514 2.9E-40 T 28-03-2018 CU254_RS17715 18696fe56f5ee58aec102d145563ffc8 547 Gene3D G3DSA:3.90.76.10 66 172 1.3E-26 T 28-03-2018 CU254_RS17715 18696fe56f5ee58aec102d145563ffc8 547 PIRSF PIRSF002741 15 545 2.6E-78 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CU254_RS11385 ee0e5271ad676122479be2ed67b4892e 151 SUPERFAMILY SSF51261 4 148 1.5E-40 T 28-03-2018 IPR011055 Duplicated hybrid motif CU254_RS11385 ee0e5271ad676122479be2ed67b4892e 151 Gene3D G3DSA:2.70.70.10 1 151 1.7E-52 T 28-03-2018 CU254_RS11385 ee0e5271ad676122479be2ed67b4892e 151 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 5 124 1.7E-43 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CU254_RS11385 ee0e5271ad676122479be2ed67b4892e 151 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 5 122 2.8E-34 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CU254_RS11385 ee0e5271ad676122479be2ed67b4892e 151 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 67 79 - T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CU254_RS05245 a743b4c2b4f58d88190cd155282efc2d 406 Gene3D G3DSA:3.30.70.270 225 405 1.5E-51 T 28-03-2018 CU254_RS05245 a743b4c2b4f58d88190cd155282efc2d 406 Pfam PF00990 Diguanylate cyclase, GGDEF domain 238 400 4.5E-42 T 28-03-2018 IPR000160 GGDEF domain CU254_RS05245 a743b4c2b4f58d88190cd155282efc2d 406 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 235 404 1.8E-45 T 28-03-2018 IPR000160 GGDEF domain CU254_RS05245 a743b4c2b4f58d88190cd155282efc2d 406 SUPERFAMILY SSF55073 244 403 1.57E-43 T 28-03-2018 IPR029787 Nucleotide cyclase CU254_RS05245 a743b4c2b4f58d88190cd155282efc2d 406 SMART SM00267 227 404 2.3E-50 T 28-03-2018 IPR000160 GGDEF domain CU254_RS27250 e2b9a7978431c5998e9aac5e942ad172 317 Pfam PF00248 Aldo/keto reductase family 11 302 5.4E-55 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS27250 e2b9a7978431c5998e9aac5e942ad172 317 SUPERFAMILY SSF51430 6 301 3.67E-68 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS27250 e2b9a7978431c5998e9aac5e942ad172 317 Gene3D G3DSA:3.20.20.100 1 317 6.1E-68 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS27250 e2b9a7978431c5998e9aac5e942ad172 317 PRINTS PR00069 Aldo-keto reductase signature 104 122 6.5E-8 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CU254_RS27250 e2b9a7978431c5998e9aac5e942ad172 317 PRINTS PR00069 Aldo-keto reductase signature 132 149 6.5E-8 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CU254_RS27250 e2b9a7978431c5998e9aac5e942ad172 317 PRINTS PR00069 Aldo-keto reductase signature 45 69 6.5E-8 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CU254_RS00095 20ade30184fee1c1867ee02b76e6d1c3 405 SUPERFAMILY SSF53474 107 369 2.55E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS00095 20ade30184fee1c1867ee02b76e6d1c3 405 Gene3D G3DSA:3.40.50.1820 100 374 5.1E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS00095 20ade30184fee1c1867ee02b76e6d1c3 405 Pfam PF00756 Putative esterase 125 321 2.4E-10 T 28-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 CU254_RS35285 f9b9cb9737388ce75128913d5b303124 153 Pfam PF03259 Roadblock/LC7 domain 24 113 2.1E-25 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain CU254_RS35285 f9b9cb9737388ce75128913d5b303124 153 SUPERFAMILY SSF103196 20 142 5.06E-34 T 28-03-2018 CU254_RS35285 f9b9cb9737388ce75128913d5b303124 153 Gene3D G3DSA:3.30.450.30 19 146 3.3E-41 T 28-03-2018 CU254_RS35285 f9b9cb9737388ce75128913d5b303124 153 SMART SM00960 24 114 4.6E-31 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain CU254_RS42045 e13857f72d554c768050eb275be0180d 357 PIRSF PIRSF000188 1 355 8.1E-129 T 28-03-2018 IPR016211 Glutamate/phenylalanine/leucine/valine dehydrogenase, bacterial/archaeal GO:0016639|GO:0055114 CU254_RS42045 e13857f72d554c768050eb275be0180d 357 SUPERFAMILY SSF53223 5 142 1.95E-42 T 28-03-2018 CU254_RS42045 e13857f72d554c768050eb275be0180d 357 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 73 86 - T 28-03-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CU254_RS42045 e13857f72d554c768050eb275be0180d 357 SMART SM00839 143 353 1.2E-40 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CU254_RS42045 e13857f72d554c768050eb275be0180d 357 SUPERFAMILY SSF51735 141 349 5.79E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS42045 e13857f72d554c768050eb275be0180d 357 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 214 317 1.3E-9 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CU254_RS42045 e13857f72d554c768050eb275be0180d 357 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 175 195 2.6E-17 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CU254_RS42045 e13857f72d554c768050eb275be0180d 357 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 287 298 2.6E-17 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CU254_RS42045 e13857f72d554c768050eb275be0180d 357 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 65 79 2.6E-17 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CU254_RS42045 e13857f72d554c768050eb275be0180d 357 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 131 153 2.6E-17 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CU254_RS42045 e13857f72d554c768050eb275be0180d 357 Gene3D G3DSA:3.40.50.720 145 338 1.7E-30 T 28-03-2018 CU254_RS42045 e13857f72d554c768050eb275be0180d 357 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 23 129 2.6E-24 T 28-03-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CU254_RS42045 e13857f72d554c768050eb275be0180d 357 Gene3D G3DSA:3.40.50.10860 11 144 6.0E-45 T 28-03-2018 CU254_RS10935 b02937b9a1a566e3fdce251d2210d985 508 Pfam PF13520 Amino acid permease 23 467 3.6E-47 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CU254_RS10935 b02937b9a1a566e3fdce251d2210d985 508 PIRSF PIRSF006060 8 507 2.9E-65 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CU254_RS02460 f86da72c5cbc1f49ede3245eaa87f045 153 Pfam PF13508 Acetyltransferase (GNAT) domain 52 126 3.0E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS02460 f86da72c5cbc1f49ede3245eaa87f045 153 SUPERFAMILY SSF55729 3 147 1.28E-25 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS02460 f86da72c5cbc1f49ede3245eaa87f045 153 Gene3D G3DSA:3.40.630.30 82 142 1.4E-10 T 28-03-2018 CU254_RS02460 f86da72c5cbc1f49ede3245eaa87f045 153 Gene3D G3DSA:3.40.630.30 1 81 1.9E-13 T 28-03-2018 CU254_RS10030 bb02127e51450ab4b780917ae14a9a23 145 SUPERFAMILY SSF55961 1 145 8.99E-32 T 28-03-2018 CU254_RS10030 bb02127e51450ab4b780917ae14a9a23 145 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 4 144 1.1E-16 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase CU254_RS10030 bb02127e51450ab4b780917ae14a9a23 145 Gene3D G3DSA:3.30.530.20 4 145 2.6E-28 T 28-03-2018 IPR023393 START-like domain CU254_RS39685 2639d1220bf0bc411baa3f0b866fa053 395 Pfam PF01168 Alanine racemase, N-terminal domain 22 263 1.5E-14 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CU254_RS39685 2639d1220bf0bc411baa3f0b866fa053 395 Gene3D G3DSA:3.20.20.10 24 283 6.4E-41 T 28-03-2018 IPR029066 PLP-binding barrel CU254_RS39685 2639d1220bf0bc411baa3f0b866fa053 395 SUPERFAMILY SSF51419 236 267 3.49E-21 T 28-03-2018 IPR029066 PLP-binding barrel CU254_RS39685 2639d1220bf0bc411baa3f0b866fa053 395 SUPERFAMILY SSF51419 23 199 3.49E-21 T 28-03-2018 IPR029066 PLP-binding barrel CU254_RS05770 02163b38a047b33e09aed2aa376c088e 202 Pfam PF07301 Protein of unknown function (DUF1453) 8 137 3.3E-6 T 28-03-2018 IPR009916 Protein of unknown function DUF1453 CU254_RS19180 24bf9618415efbdcfa3b7784d4437305 233 SUPERFAMILY SSF52218 13 205 6.68E-38 T 28-03-2018 IPR029039 Flavoprotein-like domain CU254_RS19180 24bf9618415efbdcfa3b7784d4437305 233 Gene3D G3DSA:3.40.50.360 9 214 3.4E-32 T 28-03-2018 IPR029039 Flavoprotein-like domain CU254_RS19180 24bf9618415efbdcfa3b7784d4437305 233 Pfam PF03358 NADPH-dependent FMN reductase 19 148 3.5E-13 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CU254_RS25115 0b0a22393f5fecbec326f03cc2f208ca 515 PRINTS PR01036 Tetracycline resistance protein TetB signature 411 430 2.3E-10 T 28-03-2018 CU254_RS25115 0b0a22393f5fecbec326f03cc2f208ca 515 PRINTS PR01036 Tetracycline resistance protein TetB signature 24 48 2.3E-10 T 28-03-2018 CU254_RS25115 0b0a22393f5fecbec326f03cc2f208ca 515 PRINTS PR01036 Tetracycline resistance protein TetB signature 145 169 2.3E-10 T 28-03-2018 CU254_RS25115 0b0a22393f5fecbec326f03cc2f208ca 515 PRINTS PR01036 Tetracycline resistance protein TetB signature 115 135 2.3E-10 T 28-03-2018 CU254_RS25115 0b0a22393f5fecbec326f03cc2f208ca 515 Gene3D G3DSA:1.20.1250.20 262 509 5.9E-33 T 28-03-2018 CU254_RS25115 0b0a22393f5fecbec326f03cc2f208ca 515 Gene3D G3DSA:1.20.1250.20 15 200 6.6E-29 T 28-03-2018 CU254_RS25115 0b0a22393f5fecbec326f03cc2f208ca 515 Pfam PF07690 Major Facilitator Superfamily 25 420 1.9E-42 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS25115 0b0a22393f5fecbec326f03cc2f208ca 515 SUPERFAMILY SSF103473 22 210 1.13E-59 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS25115 0b0a22393f5fecbec326f03cc2f208ca 515 SUPERFAMILY SSF103473 259 430 1.13E-59 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS25115 0b0a22393f5fecbec326f03cc2f208ca 515 SUPERFAMILY SSF103473 471 500 1.13E-59 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS11275 862b9087ee177e07c35ab64b4ff360dd 313 Pfam PF04087 Domain of unknown function (DUF389) 145 288 2.5E-27 T 28-03-2018 IPR005240 Protein of unknown function DUF389 CU254_RS06860 e882ca8dfc38560e95262add0addd595 337 SUPERFAMILY SSF48179 185 330 3.06E-67 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CU254_RS06860 e882ca8dfc38560e95262add0addd595 337 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 16 328 4.1E-131 T 28-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CU254_RS06860 e882ca8dfc38560e95262add0addd595 337 PIRSF PIRSF000116 203 334 1.1E-12 T 28-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CU254_RS06860 e882ca8dfc38560e95262add0addd595 337 PIRSF PIRSF000116 3 211 2.4E-40 T 28-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CU254_RS06860 e882ca8dfc38560e95262add0addd595 337 Gene3D G3DSA:1.10.1040.10 57 332 2.8E-118 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CU254_RS06860 e882ca8dfc38560e95262add0addd595 337 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 3 330 45.011 T 28-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CU254_RS06860 e882ca8dfc38560e95262add0addd595 337 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 16 179 2.4E-75 T 28-03-2018 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CU254_RS06860 e882ca8dfc38560e95262add0addd595 337 SUPERFAMILY SSF51735 4 184 1.62E-72 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS06860 e882ca8dfc38560e95262add0addd595 337 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 185 328 3.7E-64 T 28-03-2018 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CU254_RS32730 45a3cd56c6cdaa7ae8007416ca51caaf 338 Gene3D G3DSA:1.10.10.60 289 338 6.9E-12 T 28-03-2018 CU254_RS32730 45a3cd56c6cdaa7ae8007416ca51caaf 338 SUPERFAMILY SSF52317 16 215 4.37E-50 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS32730 45a3cd56c6cdaa7ae8007416ca51caaf 338 SUPERFAMILY SSF46689 233 282 6.99E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS32730 45a3cd56c6cdaa7ae8007416ca51caaf 338 Gene3D G3DSA:1.10.10.60 234 288 9.7E-16 T 28-03-2018 CU254_RS32730 45a3cd56c6cdaa7ae8007416ca51caaf 338 SUPERFAMILY SSF46689 286 336 2.2E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS32730 45a3cd56c6cdaa7ae8007416ca51caaf 338 SMART SM00342 249 332 1.3E-26 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS32730 45a3cd56c6cdaa7ae8007416ca51caaf 338 Gene3D G3DSA:3.40.50.880 13 233 2.0E-60 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS32730 45a3cd56c6cdaa7ae8007416ca51caaf 338 Pfam PF12833 Helix-turn-helix domain 255 334 4.3E-22 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS32730 45a3cd56c6cdaa7ae8007416ca51caaf 338 Pfam PF01965 DJ-1/PfpI family 16 194 8.3E-27 T 28-03-2018 IPR002818 DJ-1/PfpI CU254_RS17155 ff13a2c8b256a49fae71b438cae35f21 335 Gene3D G3DSA:3.40.50.2300 181 335 5.7E-27 T 28-03-2018 CU254_RS17155 ff13a2c8b256a49fae71b438cae35f21 335 SUPERFAMILY SSF53822 58 323 1.11E-31 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CU254_RS17155 ff13a2c8b256a49fae71b438cae35f21 335 SUPERFAMILY SSF47413 2 59 7.36E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS17155 ff13a2c8b256a49fae71b438cae35f21 335 Pfam PF13377 Periplasmic binding protein-like domain 168 329 3.5E-28 T 28-03-2018 CU254_RS17155 ff13a2c8b256a49fae71b438cae35f21 335 Gene3D G3DSA:3.40.50.2300 58 180 2.5E-23 T 28-03-2018 CU254_RS17155 ff13a2c8b256a49fae71b438cae35f21 335 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 47 5.5E-14 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CU254_RS17155 ff13a2c8b256a49fae71b438cae35f21 335 Gene3D G3DSA:1.10.260.40 2 57 3.5E-19 T 28-03-2018 CU254_RS17155 ff13a2c8b256a49fae71b438cae35f21 335 SMART SM00354 1 71 8.6E-20 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CU254_RS26645 59405fbd099f07f316cf7ca331d906de 150 Pfam PF00545 ribonuclease 65 144 1.3E-27 T 28-03-2018 IPR000026 Guanine-specific ribonuclease N1/T1/U2 GO:0003723|GO:0004521 CU254_RS26645 59405fbd099f07f316cf7ca331d906de 150 Gene3D G3DSA:3.10.450.30 57 149 7.6E-31 T 28-03-2018 CU254_RS26645 59405fbd099f07f316cf7ca331d906de 150 SUPERFAMILY SSF53933 59 148 6.8E-32 T 28-03-2018 IPR016191 Ribonuclease/ribotoxin GO:0003723|GO:0004540 CU254_RS16670 6f5da7ec9ccdc0092ca278f8c075997c 155 SUPERFAMILY SSF54631 10 115 1.11E-10 T 28-03-2018 CU254_RS16670 6f5da7ec9ccdc0092ca278f8c075997c 155 Gene3D G3DSA:3.20.20.70 2 116 6.3E-13 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS24030 c5d18bbd9b8edfc05a96a8083e579057 302 Gene3D G3DSA:3.40.190.10 91 188 3.1E-22 T 28-03-2018 CU254_RS24030 c5d18bbd9b8edfc05a96a8083e579057 302 Gene3D G3DSA:1.10.10.10 1 86 4.3E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS24030 c5d18bbd9b8edfc05a96a8083e579057 302 SUPERFAMILY SSF46785 5 113 9.8E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS24030 c5d18bbd9b8edfc05a96a8083e579057 302 Pfam PF03466 LysR substrate binding domain 90 293 1.4E-27 T 28-03-2018 IPR005119 LysR, substrate-binding CU254_RS24030 c5d18bbd9b8edfc05a96a8083e579057 302 Gene3D G3DSA:3.40.190.10 189 266 1.8E-12 T 28-03-2018 CU254_RS24030 c5d18bbd9b8edfc05a96a8083e579057 302 SUPERFAMILY SSF53850 92 297 1.96E-27 T 28-03-2018 CU254_RS24030 c5d18bbd9b8edfc05a96a8083e579057 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 65 5.5E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS36735 b78ed568cc115519d18853d3bf1d7cc5 305 PRINTS PR00412 Epoxide hydrolase signature 63 78 1.3E-21 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS36735 b78ed568cc115519d18853d3bf1d7cc5 305 PRINTS PR00412 Epoxide hydrolase signature 107 120 1.3E-21 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS36735 b78ed568cc115519d18853d3bf1d7cc5 305 PRINTS PR00412 Epoxide hydrolase signature 281 303 1.3E-21 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS36735 b78ed568cc115519d18853d3bf1d7cc5 305 PRINTS PR00412 Epoxide hydrolase signature 43 61 1.3E-21 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS36735 b78ed568cc115519d18853d3bf1d7cc5 305 PRINTS PR00111 Alpha/beta hydrolase fold signature 63 78 5.8E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS36735 b78ed568cc115519d18853d3bf1d7cc5 305 PRINTS PR00111 Alpha/beta hydrolase fold signature 121 134 5.8E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS36735 b78ed568cc115519d18853d3bf1d7cc5 305 PRINTS PR00111 Alpha/beta hydrolase fold signature 107 120 5.8E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS36735 b78ed568cc115519d18853d3bf1d7cc5 305 SUPERFAMILY SSF53474 15 304 2.18E-69 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS36735 b78ed568cc115519d18853d3bf1d7cc5 305 Pfam PF00561 alpha/beta hydrolase fold 37 140 2.6E-24 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS36735 b78ed568cc115519d18853d3bf1d7cc5 305 Gene3D G3DSA:3.40.50.1820 14 305 9.4E-55 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS12330 463b83c6861eafbb31fb2d2934cb990d 114 Pfam PF12973 ChrR Cupin-like domain 21 107 7.6E-10 T 28-03-2018 IPR025979 ChrR-like cupin domain CU254_RS12330 463b83c6861eafbb31fb2d2934cb990d 114 Gene3D G3DSA:2.60.120.10 1 111 3.9E-17 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS12330 463b83c6861eafbb31fb2d2934cb990d 114 SUPERFAMILY SSF51182 4 109 6.1E-18 T 28-03-2018 IPR011051 RmlC-like cupin domain CU254_RS06640 fcdc797d9fdac317f58e3e4a442faa20 418 SUPERFAMILY SSF53686 11 361 3.14E-92 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CU254_RS06640 fcdc797d9fdac317f58e3e4a442faa20 418 Gene3D G3DSA:3.40.50.1100 34 143 1.9E-29 T 28-03-2018 CU254_RS06640 fcdc797d9fdac317f58e3e4a442faa20 418 TIGRFAM TIGR02079 THD1: threonine dehydratase 11 418 6.0E-170 T 28-03-2018 IPR011820 L-threonine dehydratase biosynthetic IlvA GO:0004794 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 CU254_RS06640 fcdc797d9fdac317f58e3e4a442faa20 418 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 47 60 - T 28-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 CU254_RS06640 fcdc797d9fdac317f58e3e4a442faa20 418 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 325 417 1.5E-26 T 28-03-2018 IPR001721 ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 CU254_RS06640 fcdc797d9fdac317f58e3e4a442faa20 418 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 20 312 6.3E-77 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CU254_RS06640 fcdc797d9fdac317f58e3e4a442faa20 418 Gene3D G3DSA:3.40.50.1100 144 330 4.3E-41 T 28-03-2018 CU254_RS05995 1492d666f33d1dee837a083b37928010 128 Gene3D G3DSA:2.30.110.10 1 126 1.4E-25 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS05995 1492d666f33d1dee837a083b37928010 128 SUPERFAMILY SSF50475 5 126 1.63E-24 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS05995 1492d666f33d1dee837a083b37928010 128 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 4 91 3.7E-10 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CU254_RS35565 9c7f641b37e0f11e673337fcfe2d77ce 320 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 5 299 1.1E-23 T 28-03-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 CU254_RS35565 9c7f641b37e0f11e673337fcfe2d77ce 320 Gene3D G3DSA:3.30.420.40 124 282 4.7E-41 T 28-03-2018 CU254_RS35565 9c7f641b37e0f11e673337fcfe2d77ce 320 SUPERFAMILY SSF53067 115 300 2.39E-33 T 28-03-2018 CU254_RS35565 9c7f641b37e0f11e673337fcfe2d77ce 320 Gene3D G3DSA:3.30.420.40 2 123 2.6E-15 T 28-03-2018 CU254_RS35565 9c7f641b37e0f11e673337fcfe2d77ce 320 SUPERFAMILY SSF53067 3 111 8.55E-13 T 28-03-2018 CU254_RS25715 dd4855581bb0f1219fc6d0279b237c9f 717 Gene3D G3DSA:3.40.50.300 655 717 8.4E-8 T 28-03-2018 CU254_RS25715 dd4855581bb0f1219fc6d0279b237c9f 717 Pfam PF09848 Uncharacterized conserved protein (DUF2075) 184 230 7.1E-5 T 28-03-2018 IPR018647 Domain of unknown function DUF2075 CU254_RS25715 dd4855581bb0f1219fc6d0279b237c9f 717 SUPERFAMILY SSF52540 484 705 4.36E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS25715 dd4855581bb0f1219fc6d0279b237c9f 717 SUPERFAMILY SSF52540 162 240 4.36E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS25715 dd4855581bb0f1219fc6d0279b237c9f 717 SUPERFAMILY SSF52540 370 451 4.36E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS25715 dd4855581bb0f1219fc6d0279b237c9f 717 Gene3D G3DSA:3.40.50.300 167 567 2.6E-32 T 28-03-2018 CU254_RS30250 4116da97a09d480795be083a30758a28 334 SUPERFAMILY SSF52922 193 322 6.81E-41 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CU254_RS30250 4116da97a09d480795be083a30758a28 334 Pfam PF02779 Transketolase, pyrimidine binding domain 5 178 2.3E-44 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CU254_RS30250 4116da97a09d480795be083a30758a28 334 Pfam PF02780 Transketolase, C-terminal domain 195 315 1.5E-41 T 28-03-2018 IPR033248 Transketolase, C-terminal domain CU254_RS30250 4116da97a09d480795be083a30758a28 334 SMART SM00861 5 180 3.0E-63 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CU254_RS30250 4116da97a09d480795be083a30758a28 334 Gene3D G3DSA:3.40.50.920 195 323 1.0E-38 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CU254_RS30250 4116da97a09d480795be083a30758a28 334 Gene3D G3DSA:3.40.50.970 1 194 2.8E-60 T 28-03-2018 CU254_RS30250 4116da97a09d480795be083a30758a28 334 SUPERFAMILY SSF52518 5 185 4.26E-65 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS41010 f10ef925103348323e1226a2c4840b12 150 Pfam PF05014 Nucleoside 2-deoxyribosyltransferase 4 109 4.3E-14 T 28-03-2018 IPR007710 Nucleoside 2-deoxyribosyltransferase GO:0009159|GO:0050144|GO:0070694 Reactome: R-HSA-74259 CU254_RS41010 f10ef925103348323e1226a2c4840b12 150 Gene3D G3DSA:3.40.50.450 1 147 6.4E-23 T 28-03-2018 CU254_RS41010 f10ef925103348323e1226a2c4840b12 150 SUPERFAMILY SSF52309 3 133 9.46E-22 T 28-03-2018 CU254_RS39455 64888b12d56a7112dd396ae53509f47c 204 SUPERFAMILY SSF46689 9 87 1.45E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS39455 64888b12d56a7112dd396ae53509f47c 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 65 1.8E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS39455 64888b12d56a7112dd396ae53509f47c 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 1.9E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS39455 64888b12d56a7112dd396ae53509f47c 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 1.9E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS39455 64888b12d56a7112dd396ae53509f47c 204 SUPERFAMILY SSF48498 85 189 1.01E-11 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS39455 64888b12d56a7112dd396ae53509f47c 204 Gene3D G3DSA:1.10.260.40 50 178 5.7E-11 T 28-03-2018 CU254_RS39455 64888b12d56a7112dd396ae53509f47c 204 Gene3D G3DSA:1.10.10.60 2 49 1.7E-15 T 28-03-2018 CU254_RS22910 96355a1918af9c430031dfd03e89248c 204 SMART SM00448 18 129 3.6E-36 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS22910 96355a1918af9c430031dfd03e89248c 204 Pfam PF03861 ANTAR domain 149 200 2.3E-22 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 CU254_RS22910 96355a1918af9c430031dfd03e89248c 204 SMART SM01012 145 200 1.6E-26 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 CU254_RS22910 96355a1918af9c430031dfd03e89248c 204 PIRSF PIRSF036382 7 204 1.5E-72 T 28-03-2018 IPR008327 Signal transduction response regulator, antiterminator CU254_RS22910 96355a1918af9c430031dfd03e89248c 204 Gene3D G3DSA:1.10.10.10 158 202 1.7E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS22910 96355a1918af9c430031dfd03e89248c 204 SUPERFAMILY SSF52172 15 200 1.32E-58 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS22910 96355a1918af9c430031dfd03e89248c 204 Pfam PF00072 Response regulator receiver domain 20 129 6.3E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS22910 96355a1918af9c430031dfd03e89248c 204 Gene3D G3DSA:3.40.50.2300 15 157 5.7E-34 T 28-03-2018 CU254_RS12055 178605de470095f18054500c5e8f7b2a 217 SUPERFAMILY SSF54909 43 111 8.31E-9 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS12055 178605de470095f18054500c5e8f7b2a 217 SUPERFAMILY SSF54909 114 216 1.02E-18 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS12055 178605de470095f18054500c5e8f7b2a 217 Gene3D G3DSA:3.30.70.100 111 217 6.8E-13 T 28-03-2018 CU254_RS12055 178605de470095f18054500c5e8f7b2a 217 Gene3D G3DSA:3.30.70.100 35 89 2.6E-6 T 28-03-2018 CU254_RS12055 178605de470095f18054500c5e8f7b2a 217 Pfam PF07978 NIPSNAP 121 215 4.7E-11 T 28-03-2018 IPR012577 NIPSNAP CU254_RS19325 9057a0a7ccb2a214e0460518dac48778 337 Gene3D G3DSA:1.50.10.10 9 334 6.6E-24 T 28-03-2018 CU254_RS19325 9057a0a7ccb2a214e0460518dac48778 337 SUPERFAMILY SSF48208 13 330 6.46E-36 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CU254_RS13905 3ff17c23a36f8d055b23560d4b596cda 333 SMART SM00729 28 224 0.0036 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CU254_RS13905 3ff17c23a36f8d055b23560d4b596cda 333 TIGRFAM TIGR03470 HpnH: hopanoid biosynthesis associated radical SAM protein HpnH 1 317 6.9E-152 T 28-03-2018 IPR017833 Hopanoid biosynthesis associated radical SAM protein HpnH CU254_RS13905 3ff17c23a36f8d055b23560d4b596cda 333 SUPERFAMILY SSF102114 25 307 8.63E-54 T 28-03-2018 CU254_RS13905 3ff17c23a36f8d055b23560d4b596cda 333 Gene3D G3DSA:3.20.20.70 21 329 8.1E-35 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS13905 3ff17c23a36f8d055b23560d4b596cda 333 Pfam PF04055 Radical SAM superfamily 34 187 2.8E-17 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CU254_RS13905 3ff17c23a36f8d055b23560d4b596cda 333 Pfam PF11946 Domain of unknown function (DUF3463) 195 327 5.2E-55 T 28-03-2018 IPR022563 Domain of unknown function DUF3463 CU254_RS02435 d94cd853acad6fcaf8c598f1ff4d009d 409 SUPERFAMILY SSF103473 6 393 1.44E-34 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS02435 d94cd853acad6fcaf8c598f1ff4d009d 409 Gene3D G3DSA:1.20.1250.20 2 194 9.5E-9 T 28-03-2018 CU254_RS02435 d94cd853acad6fcaf8c598f1ff4d009d 409 Gene3D G3DSA:1.20.1250.20 202 404 1.1E-16 T 28-03-2018 CU254_RS02435 d94cd853acad6fcaf8c598f1ff4d009d 409 Pfam PF07690 Major Facilitator Superfamily 8 327 4.5E-20 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS41250 5e899618d9e026fd8069e91f4eae579d 332 SUPERFAMILY SSF53850 58 279 6.39E-33 T 28-03-2018 CU254_RS41250 5e899618d9e026fd8069e91f4eae579d 332 Gene3D G3DSA:3.40.190.10 148 331 1.4E-30 T 28-03-2018 CU254_RS41250 5e899618d9e026fd8069e91f4eae579d 332 Gene3D G3DSA:3.40.190.10 46 147 2.3E-6 T 28-03-2018 CU254_RS41250 5e899618d9e026fd8069e91f4eae579d 332 Pfam PF09084 NMT1/THI5 like 59 271 7.1E-22 T 28-03-2018 IPR015168 SsuA/THI5-like CU254_RS18235 d9eeefa5ba11a6246c04f06b074921e5 287 TIGRFAM TIGR03690 20S_bact_beta: proteasome, beta subunit 53 278 8.0E-104 T 28-03-2018 IPR022483 Peptidase T1A, proteasome beta-subunit, actinobacteria GO:0004298|GO:0005839|GO:0010498 CU254_RS18235 d9eeefa5ba11a6246c04f06b074921e5 287 Hamap MF_02113_B Proteasome subunit beta [prcB]. 11 284 47.696 T 28-03-2018 IPR022483 Peptidase T1A, proteasome beta-subunit, actinobacteria GO:0004298|GO:0005839|GO:0010498 CU254_RS18235 d9eeefa5ba11a6246c04f06b074921e5 287 Pfam PF00227 Proteasome subunit 55 239 7.8E-31 T 28-03-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-446652|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8941858|Reactome: R-HSA-8951664|Reactome: R-HSA-983168 CU254_RS18235 d9eeefa5ba11a6246c04f06b074921e5 287 Gene3D G3DSA:3.60.20.10 51 284 1.2E-40 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CU254_RS18235 d9eeefa5ba11a6246c04f06b074921e5 287 SUPERFAMILY SSF56235 24 264 4.89E-51 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CU254_RS27395 14d57ff43fc465fc904e73f46d63d812 163 Gene3D G3DSA:3.40.630.30 2 150 5.0E-24 T 28-03-2018 CU254_RS27395 14d57ff43fc465fc904e73f46d63d812 163 Pfam PF00583 Acetyltransferase (GNAT) family 66 131 1.3E-9 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS27395 14d57ff43fc465fc904e73f46d63d812 163 SUPERFAMILY SSF55729 2 138 1.63E-25 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS13475 fd32dc3348cd308e583158722e51ebda 243 SUPERFAMILY SSF48008 95 221 1.44E-21 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS13475 fd32dc3348cd308e583158722e51ebda 243 Gene3D G3DSA:1.10.10.10 1 71 5.1E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS13475 fd32dc3348cd308e583158722e51ebda 243 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 29 43 2.0E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS13475 fd32dc3348cd308e583158722e51ebda 243 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 59 2.0E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS13475 fd32dc3348cd308e583158722e51ebda 243 SUPERFAMILY SSF46785 5 78 1.59E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS13475 fd32dc3348cd308e583158722e51ebda 243 SMART SM00345 10 69 4.7E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS13475 fd32dc3348cd308e583158722e51ebda 243 SMART SM00895 98 217 1.7E-15 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS13475 fd32dc3348cd308e583158722e51ebda 243 Gene3D G3DSA:1.20.120.530 92 226 1.2E-21 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS13475 fd32dc3348cd308e583158722e51ebda 243 Pfam PF07729 FCD domain 98 216 5.3E-18 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS13475 fd32dc3348cd308e583158722e51ebda 243 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 69 1.0E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS31645 beac09b27f0e5abd6b6690aa7e8f5595 526 SUPERFAMILY SSF52540 366 520 2.09E-32 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS31645 beac09b27f0e5abd6b6690aa7e8f5595 526 Pfam PF00005 ABC transporter 32 195 3.6E-18 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS31645 beac09b27f0e5abd6b6690aa7e8f5595 526 Pfam PF00005 ABC transporter 366 484 1.2E-19 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS31645 beac09b27f0e5abd6b6690aa7e8f5595 526 SUPERFAMILY SSF52540 136 250 1.5E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS31645 beac09b27f0e5abd6b6690aa7e8f5595 526 SUPERFAMILY SSF52540 11 92 1.5E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS31645 beac09b27f0e5abd6b6690aa7e8f5595 526 SMART SM00382 372 526 9.5E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS31645 beac09b27f0e5abd6b6690aa7e8f5595 526 SMART SM00382 39 240 3.7E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS31645 beac09b27f0e5abd6b6690aa7e8f5595 526 Gene3D G3DSA:3.40.50.300 361 521 2.5E-32 T 28-03-2018 CU254_RS31645 beac09b27f0e5abd6b6690aa7e8f5595 526 Gene3D G3DSA:3.40.50.300 11 292 5.6E-43 T 28-03-2018 CU254_RS35695 196c02dce1f23d74390f32eabcfba953 545 SUPERFAMILY SSF52096 15 236 1.67E-31 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS35695 196c02dce1f23d74390f32eabcfba953 545 SUPERFAMILY SSF52096 295 535 9.95E-15 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS35695 196c02dce1f23d74390f32eabcfba953 545 Pfam PF00378 Enoyl-CoA hydratase/isomerase 48 236 8.9E-21 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CU254_RS35695 196c02dce1f23d74390f32eabcfba953 545 TIGRFAM TIGR03222 benzo_boxC: benzoyl-CoA-dihydrodiol lyase 7 545 1.4E-253 T 28-03-2018 IPR017633 Benzoyl-CoA-dihydrodiol lyase MetaCyc: PWY-1361 CU254_RS35695 196c02dce1f23d74390f32eabcfba953 545 Gene3D G3DSA:3.90.226.10 246 530 2.5E-22 T 28-03-2018 CU254_RS35695 196c02dce1f23d74390f32eabcfba953 545 Gene3D G3DSA:3.90.226.10 2 244 1.4E-38 T 28-03-2018 CU254_RS24475 57b8ff4c52060f17572dbb912c67543b 477 Pfam PF07690 Major Facilitator Superfamily 10 391 1.2E-49 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS24475 57b8ff4c52060f17572dbb912c67543b 477 Gene3D G3DSA:1.20.1250.20 241 442 3.4E-27 T 28-03-2018 CU254_RS24475 57b8ff4c52060f17572dbb912c67543b 477 Gene3D G3DSA:1.20.1250.20 1 192 2.7E-30 T 28-03-2018 CU254_RS24475 57b8ff4c52060f17572dbb912c67543b 477 SUPERFAMILY SSF103473 230 439 9.94E-65 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS24475 57b8ff4c52060f17572dbb912c67543b 477 SUPERFAMILY SSF103473 3 187 9.94E-65 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS11260 6eb0e1f7923cee74675d2e1994e3c896 618 SUPERFAMILY SSF102114 407 545 2.55E-9 T 28-03-2018 CU254_RS11260 6eb0e1f7923cee74675d2e1994e3c896 618 SMART SM00306 49 141 6.6E-8 T 28-03-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CU254_RS11260 6eb0e1f7923cee74675d2e1994e3c896 618 SUPERFAMILY SSF51294 282 342 1.83E-19 T 28-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CU254_RS11260 6eb0e1f7923cee74675d2e1994e3c896 618 SUPERFAMILY SSF51294 51 180 1.83E-19 T 28-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CU254_RS11260 6eb0e1f7923cee74675d2e1994e3c896 618 Gene3D G3DSA:3.20.20.70 337 599 1.1E-24 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS11260 6eb0e1f7923cee74675d2e1994e3c896 618 SMART SM00305 304 348 1.9E-4 T 28-03-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CU254_RS11260 6eb0e1f7923cee74675d2e1994e3c896 618 Gene3D G3DSA:2.170.16.10 36 336 2.6E-23 T 28-03-2018 CU254_RS07455 3bf2288c60e813a0d17a7d2c792b9c38 398 Gene3D G3DSA:1.20.1250.20 1 190 3.8E-29 T 28-03-2018 CU254_RS07455 3bf2288c60e813a0d17a7d2c792b9c38 398 Pfam PF07690 Major Facilitator Superfamily 13 349 4.9E-41 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS07455 3bf2288c60e813a0d17a7d2c792b9c38 398 SUPERFAMILY SSF103473 2 385 9.81E-58 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS07455 3bf2288c60e813a0d17a7d2c792b9c38 398 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 4 382 3.1E-97 T 28-03-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 CU254_RS07455 3bf2288c60e813a0d17a7d2c792b9c38 398 ProSitePatterns PS00216 Sugar transport proteins signature 1. 57 73 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CU254_RS07455 3bf2288c60e813a0d17a7d2c792b9c38 398 Gene3D G3DSA:1.20.1250.20 192 398 8.9E-14 T 28-03-2018 CU254_RS03150 17ddc2bee4962136a6b9267b445fd6b8 140 Gene3D G3DSA:3.10.490.10 1 135 1.3E-29 T 28-03-2018 CU254_RS03150 17ddc2bee4962136a6b9267b445fd6b8 140 SUPERFAMILY SSF110857 5 109 4.45E-12 T 28-03-2018 IPR013024 Gamma-glutamyl cyclotransferase-like CU254_RS03150 17ddc2bee4962136a6b9267b445fd6b8 140 Pfam PF13772 AIG2-like family 49 130 3.2E-23 T 28-03-2018 CU254_RS16875 8223e1c522fdcc2885c74d7edb6d4cba 526 Gene3D G3DSA:3.50.50.60 1 520 3.1E-35 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS16875 8223e1c522fdcc2885c74d7edb6d4cba 526 Pfam PF01593 Flavin containing amine oxidoreductase 15 283 5.9E-12 T 28-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 CU254_RS16875 8223e1c522fdcc2885c74d7edb6d4cba 526 SUPERFAMILY SSF51905 462 493 3.75E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS16875 8223e1c522fdcc2885c74d7edb6d4cba 526 SUPERFAMILY SSF51905 4 328 3.75E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS27375 95ec5b13150eaaa1beb4c711bfaf9732 211 SMART SM00421 147 204 8.4E-25 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS27375 95ec5b13150eaaa1beb4c711bfaf9732 211 SUPERFAMILY SSF52172 5 128 8.11E-30 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS27375 95ec5b13150eaaa1beb4c711bfaf9732 211 Pfam PF00072 Response regulator receiver domain 6 117 3.5E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS27375 95ec5b13150eaaa1beb4c711bfaf9732 211 Gene3D G3DSA:3.40.50.2300 3 128 6.1E-31 T 28-03-2018 CU254_RS27375 95ec5b13150eaaa1beb4c711bfaf9732 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 3.9E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS27375 95ec5b13150eaaa1beb4c711bfaf9732 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 3.9E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS27375 95ec5b13150eaaa1beb4c711bfaf9732 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 3.9E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS27375 95ec5b13150eaaa1beb4c711bfaf9732 211 SUPERFAMILY SSF46894 138 210 2.79E-22 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS27375 95ec5b13150eaaa1beb4c711bfaf9732 211 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 204 1.1E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS27375 95ec5b13150eaaa1beb4c711bfaf9732 211 Gene3D G3DSA:1.10.10.10 129 211 2.5E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS27375 95ec5b13150eaaa1beb4c711bfaf9732 211 SMART SM00448 4 117 6.4E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS27375 95ec5b13150eaaa1beb4c711bfaf9732 211 ProSitePatterns PS00622 LuxR-type HTH domain signature. 164 191 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS05675 7c41095e445bd64ac062c624be8ef699 275 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 1 264 16.604 T 28-03-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 CU254_RS05675 7c41095e445bd64ac062c624be8ef699 275 Pfam PF01564 Spermine/spermidine synthase domain 57 203 9.6E-13 T 28-03-2018 CU254_RS05675 7c41095e445bd64ac062c624be8ef699 275 SUPERFAMILY SSF53335 9 271 1.95E-41 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS05675 7c41095e445bd64ac062c624be8ef699 275 Gene3D G3DSA:3.40.50.150 53 268 1.3E-26 T 28-03-2018 CU254_RS14980 c0b3370d8cf3ba3b734b51863bc26040 341 Pfam PF08402 TOBE domain 253 329 2.0E-13 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CU254_RS14980 c0b3370d8cf3ba3b734b51863bc26040 341 SMART SM00382 31 214 1.0E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS14980 c0b3370d8cf3ba3b734b51863bc26040 341 Pfam PF00005 ABC transporter 23 164 5.2E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS14980 c0b3370d8cf3ba3b734b51863bc26040 341 Gene3D G3DSA:3.40.50.300 2 247 5.8E-76 T 28-03-2018 CU254_RS14980 c0b3370d8cf3ba3b734b51863bc26040 341 SUPERFAMILY SSF50331 245 328 3.15E-10 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CU254_RS14980 c0b3370d8cf3ba3b734b51863bc26040 341 Gene3D G3DSA:2.40.50.140 254 322 1.1E-4 T 28-03-2018 CU254_RS14980 c0b3370d8cf3ba3b734b51863bc26040 341 SUPERFAMILY SSF52540 6 243 3.78E-86 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS14980 c0b3370d8cf3ba3b734b51863bc26040 341 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS05495 0fbb45b8234f6577831684f62ace2c1c 484 Pfam PF03704 Bacterial transcriptional activator domain 333 471 1.7E-35 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CU254_RS05495 0fbb45b8234f6577831684f62ace2c1c 484 Gene3D G3DSA:3.40.50.2300 7 133 3.5E-33 T 28-03-2018 CU254_RS05495 0fbb45b8234f6577831684f62ace2c1c 484 SMART SM01043 333 477 6.7E-42 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CU254_RS05495 0fbb45b8234f6577831684f62ace2c1c 484 Pfam PF00072 Response regulator receiver domain 10 122 1.0E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS05495 0fbb45b8234f6577831684f62ace2c1c 484 Pfam PF00196 Bacterial regulatory proteins, luxR family 158 213 1.5E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS05495 0fbb45b8234f6577831684f62ace2c1c 484 Gene3D G3DSA:1.10.10.10 228 328 1.5E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS05495 0fbb45b8234f6577831684f62ace2c1c 484 SUPERFAMILY SSF46894 234 326 4.82E-12 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS05495 0fbb45b8234f6577831684f62ace2c1c 484 SMART SM00448 8 122 5.5E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS05495 0fbb45b8234f6577831684f62ace2c1c 484 SMART SM00862 247 326 9.0E-8 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS05495 0fbb45b8234f6577831684f62ace2c1c 484 SUPERFAMILY SSF46894 148 219 3.74E-18 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS05495 0fbb45b8234f6577831684f62ace2c1c 484 Gene3D G3DSA:1.10.10.10 134 222 5.0E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS05495 0fbb45b8234f6577831684f62ace2c1c 484 Pfam PF00486 Transcriptional regulatory protein, C terminal 256 326 7.6E-10 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS05495 0fbb45b8234f6577831684f62ace2c1c 484 SUPERFAMILY SSF48452 332 477 3.16E-27 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS05495 0fbb45b8234f6577831684f62ace2c1c 484 Gene3D G3DSA:1.25.40.10 330 480 1.1E-19 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS05495 0fbb45b8234f6577831684f62ace2c1c 484 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 189 201 3.8E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS05495 0fbb45b8234f6577831684f62ace2c1c 484 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 189 3.8E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS05495 0fbb45b8234f6577831684f62ace2c1c 484 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 159 173 3.8E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS05495 0fbb45b8234f6577831684f62ace2c1c 484 SMART SM00421 156 213 2.0E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS05495 0fbb45b8234f6577831684f62ace2c1c 484 SUPERFAMILY SSF52172 8 139 3.13E-30 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS41100 c2963811a191409c5f99a67386bf8938 216 Pfam PF09076 Beta/Gamma crystallin 150 213 9.2E-10 T 28-03-2018 IPR015161 Streptomyces killer toxin-like, beta/gamma crystallin CU254_RS41100 c2963811a191409c5f99a67386bf8938 216 SUPERFAMILY SSF49695 148 208 6.87E-6 T 28-03-2018 IPR011024 Gamma-crystallin-related CU254_RS41100 c2963811a191409c5f99a67386bf8938 216 Gene3D G3DSA:2.60.20.30 141 213 5.7E-7 T 28-03-2018 IPR015791 Antimicrobial/protein inhibitor, gamma-crystallin-like CU254_RS34810 1788415dcc2e14b1e92d5932c2a70e1d 452 SUPERFAMILY SSF52425 6 174 1.57E-45 T 28-03-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 CU254_RS34810 1788415dcc2e14b1e92d5932c2a70e1d 452 PRINTS PR00147 DNA photolyase signature 329 347 1.0E-25 T 28-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 CU254_RS34810 1788415dcc2e14b1e92d5932c2a70e1d 452 PRINTS PR00147 DNA photolyase signature 138 154 1.0E-25 T 28-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 CU254_RS34810 1788415dcc2e14b1e92d5932c2a70e1d 452 PRINTS PR00147 DNA photolyase signature 309 325 1.0E-25 T 28-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 CU254_RS34810 1788415dcc2e14b1e92d5932c2a70e1d 452 PRINTS PR00147 DNA photolyase signature 368 382 1.0E-25 T 28-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 CU254_RS34810 1788415dcc2e14b1e92d5932c2a70e1d 452 Gene3D G3DSA:1.10.579.10 275 451 3.4E-69 T 28-03-2018 CU254_RS34810 1788415dcc2e14b1e92d5932c2a70e1d 452 SUPERFAMILY SSF48173 181 449 5.1E-99 T 28-03-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 CU254_RS34810 1788415dcc2e14b1e92d5932c2a70e1d 452 ProSitePatterns PS00394 DNA photolyases class 1 signature 1. 309 321 - T 28-03-2018 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal CU254_RS34810 1788415dcc2e14b1e92d5932c2a70e1d 452 Gene3D G3DSA:3.40.50.620 2 143 5.8E-41 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS34810 1788415dcc2e14b1e92d5932c2a70e1d 452 Pfam PF03441 FAD binding domain of DNA photolyase 259 446 1.1E-76 T 28-03-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 CU254_RS34810 1788415dcc2e14b1e92d5932c2a70e1d 452 Gene3D G3DSA:1.25.40.80 144 273 9.3E-37 T 28-03-2018 CU254_RS34810 1788415dcc2e14b1e92d5932c2a70e1d 452 Pfam PF00875 DNA photolyase 7 158 9.1E-43 T 28-03-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 CU254_RS39335 14fab8cadab0fa9b4408bf24e6e69fcf 354 Pfam PF09594 Glycosyltransferase family 87 37 266 6.1E-51 T 28-03-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 CU254_RS19425 5df8295f58af175366d8db3a8d3b7427 144 Pfam PF01957 NfeD-like C-terminal, partner-binding 6 140 1.1E-18 T 28-03-2018 IPR002810 NfeD-like, C-terminal domain CU254_RS19425 5df8295f58af175366d8db3a8d3b7427 144 SUPERFAMILY SSF141322 79 141 6.54E-7 T 28-03-2018 CU254_RS19425 5df8295f58af175366d8db3a8d3b7427 144 Gene3D G3DSA:2.40.50.140 75 144 1.9E-17 T 28-03-2018 CU254_RS14575 3814e84e8f949027b83a66e1abc1baac 288 Gene3D G3DSA:3.20.20.70 1 288 4.2E-76 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS14575 3814e84e8f949027b83a66e1abc1baac 288 SUPERFAMILY SSF51569 28 282 5.13E-34 T 28-03-2018 CU254_RS31455 2c24b520c00bb00c99b09d7ead407991 227 TIGRFAM TIGR04539 tRNA_cyclodipep: tRNA-dependent cyclodipeptide synthase 2 218 6.3E-73 T 28-03-2018 IPR030903 Cyclodileucine synthase GO:0016755 CU254_RS31455 2c24b520c00bb00c99b09d7ead407991 227 Pfam PF16715 Cyclodipeptide synthase 2 218 5.2E-57 T 28-03-2018 IPR030903 Cyclodileucine synthase GO:0016755 CU254_RS10735 03aa12bd2ca716c448d104729b899e3b 581 SUPERFAMILY SSF52540 21 179 2.17E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS10735 03aa12bd2ca716c448d104729b899e3b 581 SUPERFAMILY SSF52540 137 207 1.3E-17 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS10735 03aa12bd2ca716c448d104729b899e3b 581 SUPERFAMILY SSF52540 267 388 1.3E-17 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS10735 03aa12bd2ca716c448d104729b899e3b 581 Gene3D G3DSA:3.40.50.300 266 523 7.9E-9 T 28-03-2018 CU254_RS10735 03aa12bd2ca716c448d104729b899e3b 581 Pfam PF04851 Type III restriction enzyme, res subunit 23 175 6.7E-13 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CU254_RS10735 03aa12bd2ca716c448d104729b899e3b 581 SMART SM00487 19 197 1.6E-12 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CU254_RS10735 03aa12bd2ca716c448d104729b899e3b 581 Gene3D G3DSA:3.40.50.300 11 182 2.1E-19 T 28-03-2018 CU254_RS39570 07daab101d7dcb741291d6d31878946e 124 SUPERFAMILY SSF54534 15 123 8.45E-40 T 28-03-2018 CU254_RS39570 07daab101d7dcb741291d6d31878946e 124 Gene3D G3DSA:3.10.50.40 3 124 1.1E-41 T 28-03-2018 CU254_RS39570 07daab101d7dcb741291d6d31878946e 124 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 30 121 3.8E-33 T 28-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain CU254_RS27380 7ca329d334d37951e2cc87859fd009c0 381 SUPERFAMILY SSF55874 273 380 6.21E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS27380 7ca329d334d37951e2cc87859fd009c0 381 Pfam PF07730 Histidine kinase 196 263 2.1E-14 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CU254_RS27380 7ca329d334d37951e2cc87859fd009c0 381 Gene3D G3DSA:3.30.565.10 268 381 7.4E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS31765 bff1ab034447860b8c1ef706a9a0da57 411 Pfam PF13556 PucR C-terminal helix-turn-helix domain 341 397 1.0E-18 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CU254_RS31765 bff1ab034447860b8c1ef706a9a0da57 411 Gene3D G3DSA:1.10.10.60 338 377 1.9E-5 T 28-03-2018 CU254_RS10620 3f84a1d17b71a630cd508b96a571e723 258 SMART SM00866 109 249 3.2E-32 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CU254_RS10620 3f84a1d17b71a630cd508b96a571e723 258 Gene3D G3DSA:1.10.10.10 10 91 5.1E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS10620 3f84a1d17b71a630cd508b96a571e723 258 SMART SM00345 32 89 8.1E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS10620 3f84a1d17b71a630cd508b96a571e723 258 Pfam PF07702 UTRA domain 110 248 4.1E-32 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CU254_RS10620 3f84a1d17b71a630cd508b96a571e723 258 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 63 2.8E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS10620 3f84a1d17b71a630cd508b96a571e723 258 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 63 79 2.8E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS10620 3f84a1d17b71a630cd508b96a571e723 258 SUPERFAMILY SSF46785 24 98 7.88E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS10620 3f84a1d17b71a630cd508b96a571e723 258 Gene3D G3DSA:3.40.1410.10 93 258 1.8E-38 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CU254_RS10620 3f84a1d17b71a630cd508b96a571e723 258 Pfam PF00392 Bacterial regulatory proteins, gntR family 42 89 3.2E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS10620 3f84a1d17b71a630cd508b96a571e723 258 SUPERFAMILY SSF64288 77 256 1.15E-46 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CU254_RS29070 e63311d984177930cf5cba56f63e8b8e 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 301 3.5E-23 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS29070 e63311d984177930cf5cba56f63e8b8e 308 Gene3D G3DSA:1.10.3720.10 1 291 3.8E-36 T 28-03-2018 CU254_RS29070 e63311d984177930cf5cba56f63e8b8e 308 SUPERFAMILY SSF161098 83 283 3.01E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS19695 4cf7c450bfb214f7099c533fdcdd5a31 286 SUPERFAMILY SSF48498 167 280 9.49E-19 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS19695 4cf7c450bfb214f7099c533fdcdd5a31 286 Gene3D G3DSA:1.10.357.10 151 284 3.4E-17 T 28-03-2018 CU254_RS19695 4cf7c450bfb214f7099c533fdcdd5a31 286 Gene3D G3DSA:1.10.10.60 73 122 1.2E-15 T 28-03-2018 CU254_RS19695 4cf7c450bfb214f7099c533fdcdd5a31 286 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 101 114 1.7E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS19695 4cf7c450bfb214f7099c533fdcdd5a31 286 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 122 145 1.7E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS19695 4cf7c450bfb214f7099c533fdcdd5a31 286 Gene3D G3DSA:1.10.260.40 123 150 4.1E-13 T 28-03-2018 CU254_RS19695 4cf7c450bfb214f7099c533fdcdd5a31 286 Gene3D G3DSA:1.10.260.40 2 72 7.6E-13 T 28-03-2018 CU254_RS19695 4cf7c450bfb214f7099c533fdcdd5a31 286 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 170 280 8.7E-28 T 28-03-2018 CU254_RS19695 4cf7c450bfb214f7099c533fdcdd5a31 286 Pfam PF00440 Bacterial regulatory proteins, tetR family 101 147 4.6E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS19695 4cf7c450bfb214f7099c533fdcdd5a31 286 SUPERFAMILY SSF46689 94 173 7.28E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS19695 4cf7c450bfb214f7099c533fdcdd5a31 286 SUPERFAMILY SSF47413 5 72 3.75E-10 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS19695 4cf7c450bfb214f7099c533fdcdd5a31 286 SMART SM00530 10 65 1.8E-5 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS19790 7d2c0625cb35a5efbbda7b7bb53c8f5b 463 Pfam PF00324 Amino acid permease 22 456 2.3E-114 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CU254_RS19790 7d2c0625cb35a5efbbda7b7bb53c8f5b 463 PIRSF PIRSF006060 1 462 1.2E-65 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CU254_RS19790 7d2c0625cb35a5efbbda7b7bb53c8f5b 463 ProSitePatterns PS00218 Amino acid permeases signature. 46 76 - T 28-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CU254_RS10355 1c175e420f9f8363eaaf258d1dadb7e0 464 TIGRFAM TIGR02946 acyl_WS_DGAT: acyltransferase, WS/DGAT/MGAT 4 462 3.1E-146 T 28-03-2018 IPR014292 Acyltransferase, WS/DGAT/MGAT GO:0016746|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CU254_RS10355 1c175e420f9f8363eaaf258d1dadb7e0 464 Gene3D G3DSA:3.30.559.10 2 180 5.2E-8 T 28-03-2018 CU254_RS10355 1c175e420f9f8363eaaf258d1dadb7e0 464 SUPERFAMILY SSF52777 5 166 8.45E-11 T 28-03-2018 CU254_RS10355 1c175e420f9f8363eaaf258d1dadb7e0 464 Gene3D G3DSA:3.30.70.270 181 318 4.1E-4 T 28-03-2018 CU254_RS10355 1c175e420f9f8363eaaf258d1dadb7e0 464 Pfam PF06974 Protein of unknown function (DUF1298) 309 458 2.1E-28 T 28-03-2018 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CU254_RS10355 1c175e420f9f8363eaaf258d1dadb7e0 464 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 4 267 4.3E-74 T 28-03-2018 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CU254_RS06925 d115795f28768dc2f22b25730ba451cc 1089 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 170 181 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CU254_RS06925 d115795f28768dc2f22b25730ba451cc 1089 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 588 598 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CU254_RS06925 d115795f28768dc2f22b25730ba451cc 1089 Pfam PF00082 Subtilase family 165 626 3.1E-35 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS06925 d115795f28768dc2f22b25730ba451cc 1089 Gene3D G3DSA:3.40.50.200 136 659 3.0E-64 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS06925 d115795f28768dc2f22b25730ba451cc 1089 PRINTS PR00723 Subtilisin serine protease family (S8) signature 240 253 6.2E-17 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CU254_RS06925 d115795f28768dc2f22b25730ba451cc 1089 PRINTS PR00723 Subtilisin serine protease family (S8) signature 165 184 6.2E-17 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CU254_RS06925 d115795f28768dc2f22b25730ba451cc 1089 PRINTS PR00723 Subtilisin serine protease family (S8) signature 587 603 6.2E-17 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CU254_RS06925 d115795f28768dc2f22b25730ba451cc 1089 Gene3D G3DSA:2.60.40.1710 660 786 5.8E-4 T 28-03-2018 CU254_RS06925 d115795f28768dc2f22b25730ba451cc 1089 Pfam PF02225 PA domain 424 489 2.3E-7 T 28-03-2018 IPR003137 PA domain CU254_RS06925 d115795f28768dc2f22b25730ba451cc 1089 SUPERFAMILY SSF52743 112 387 2.88E-60 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS06925 d115795f28768dc2f22b25730ba451cc 1089 SUPERFAMILY SSF52743 543 653 2.88E-60 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS06925 d115795f28768dc2f22b25730ba451cc 1089 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 244 254 - T 28-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site CU254_RS03720 b550c2bdeba42c582afba56f6db4dee2 187 SUPERFAMILY SSF48150 11 186 2.44E-71 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CU254_RS03720 b550c2bdeba42c582afba56f6db4dee2 187 Gene3D G3DSA:1.10.340.30 10 186 5.8E-79 T 28-03-2018 CU254_RS03720 b550c2bdeba42c582afba56f6db4dee2 187 Pfam PF03352 Methyladenine glycosylase 15 185 1.4E-71 T 28-03-2018 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 CU254_RS03720 b550c2bdeba42c582afba56f6db4dee2 187 TIGRFAM TIGR00624 tag: DNA-3-methyladenine glycosylase I 12 185 3.9E-77 T 28-03-2018 IPR004597 DNA-3-methyladenine glycosylase I GO:0006284|GO:0008725 CU254_RS40170 042b637b0d08f94b6c6314b25b4b356b 304 SUPERFAMILY SSF53474 20 304 2.63E-51 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS40170 042b637b0d08f94b6c6314b25b4b356b 304 PRINTS PR00111 Alpha/beta hydrolase fold signature 76 91 1.2E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS40170 042b637b0d08f94b6c6314b25b4b356b 304 PRINTS PR00111 Alpha/beta hydrolase fold signature 123 136 1.2E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS40170 042b637b0d08f94b6c6314b25b4b356b 304 PRINTS PR00412 Epoxide hydrolase signature 56 74 3.7E-16 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS40170 042b637b0d08f94b6c6314b25b4b356b 304 PRINTS PR00412 Epoxide hydrolase signature 123 136 3.7E-16 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS40170 042b637b0d08f94b6c6314b25b4b356b 304 PRINTS PR00412 Epoxide hydrolase signature 76 91 3.7E-16 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS40170 042b637b0d08f94b6c6314b25b4b356b 304 PRINTS PR00412 Epoxide hydrolase signature 279 301 3.7E-16 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS40170 042b637b0d08f94b6c6314b25b4b356b 304 Pfam PF00561 alpha/beta hydrolase fold 50 165 1.2E-18 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS40170 042b637b0d08f94b6c6314b25b4b356b 304 Gene3D G3DSA:3.40.50.1820 3 304 3.2E-42 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS36275 0d4f1a5e21444d983ad3c6b2d20535b3 164 Gene3D G3DSA:2.40.40.20 1 117 1.7E-54 T 28-03-2018 CU254_RS36275 0d4f1a5e21444d983ad3c6b2d20535b3 164 Pfam PF02261 Aspartate decarboxylase 1 114 2.9E-52 T 28-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CU254_RS36275 0d4f1a5e21444d983ad3c6b2d20535b3 164 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 130 75.821 T 28-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CU254_RS36275 0d4f1a5e21444d983ad3c6b2d20535b3 164 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 95 2.0E-39 T 28-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CU254_RS36275 0d4f1a5e21444d983ad3c6b2d20535b3 164 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 120 4.8E-53 T 28-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CU254_RS36275 0d4f1a5e21444d983ad3c6b2d20535b3 164 SUPERFAMILY SSF50692 1 116 1.57E-49 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain CU254_RS26085 29d7c97ba50dc2ad9d999f7e4a61ed5e 366 Pfam PF07687 Peptidase dimerisation domain 172 265 2.4E-20 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CU254_RS26085 29d7c97ba50dc2ad9d999f7e4a61ed5e 366 Gene3D G3DSA:3.30.70.360 180 279 3.9E-22 T 28-03-2018 CU254_RS26085 29d7c97ba50dc2ad9d999f7e4a61ed5e 366 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 74 83 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CU254_RS26085 29d7c97ba50dc2ad9d999f7e4a61ed5e 366 Pfam PF01546 Peptidase family M20/M25/M40 76 360 1.7E-21 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CU254_RS26085 29d7c97ba50dc2ad9d999f7e4a61ed5e 366 SUPERFAMILY SSF55031 175 266 3.01E-22 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CU254_RS26085 29d7c97ba50dc2ad9d999f7e4a61ed5e 366 PIRSF PIRSF037238 1 364 4.5E-115 T 28-03-2018 IPR017150 Peptidase M20, glutamate carboxypeptidase CU254_RS26085 29d7c97ba50dc2ad9d999f7e4a61ed5e 366 Gene3D G3DSA:3.40.630.10 4 179 1.1E-18 T 28-03-2018 CU254_RS26085 29d7c97ba50dc2ad9d999f7e4a61ed5e 366 SUPERFAMILY SSF53187 289 363 4.28E-39 T 28-03-2018 CU254_RS26085 29d7c97ba50dc2ad9d999f7e4a61ed5e 366 SUPERFAMILY SSF53187 7 184 4.28E-39 T 28-03-2018 CU254_RS08725 9fc5b0d66f7d2e04ea76f7239ade7d24 206 ProSitePatterns PS01081 TetR-type HTH domain signature. 28 58 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CU254_RS08725 9fc5b0d66f7d2e04ea76f7239ade7d24 206 Gene3D G3DSA:1.10.260.40 38 64 9.7E-15 T 28-03-2018 CU254_RS08725 9fc5b0d66f7d2e04ea76f7239ade7d24 206 SUPERFAMILY SSF46689 2 87 1.65E-21 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS08725 9fc5b0d66f7d2e04ea76f7239ade7d24 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 8.2E-19 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS08725 9fc5b0d66f7d2e04ea76f7239ade7d24 206 Gene3D G3DSA:1.10.357.10 65 196 2.0E-14 T 28-03-2018 CU254_RS08725 9fc5b0d66f7d2e04ea76f7239ade7d24 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 9.6E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS08725 9fc5b0d66f7d2e04ea76f7239ade7d24 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 9.6E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS08725 9fc5b0d66f7d2e04ea76f7239ade7d24 206 Gene3D G3DSA:1.10.10.60 2 37 6.9E-17 T 28-03-2018 CU254_RS33770 c51eaa9e2faaaf531b37d21f99960227 290 TIGRFAM TIGR03621 F420_MSMEG_2516: probable F420-dependent oxidoreductase, MSMEG_2516 family 4 288 9.9E-90 T 28-03-2018 IPR019923 Luciferase-like, F420-dependent oxidoreductase, MSMEG2516, predicted CU254_RS33770 c51eaa9e2faaaf531b37d21f99960227 290 Pfam PF00296 Luciferase-like monooxygenase 18 237 1.2E-25 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS33770 c51eaa9e2faaaf531b37d21f99960227 290 Gene3D G3DSA:3.20.20.30 13 288 1.0E-44 T 28-03-2018 CU254_RS33770 c51eaa9e2faaaf531b37d21f99960227 290 SUPERFAMILY SSF51679 4 278 1.57E-41 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS06850 b6df91b2c3079a63acd3c24473767e4a 595 Gene3D G3DSA:3.40.50.970 352 563 1.4E-51 T 28-03-2018 CU254_RS06850 b6df91b2c3079a63acd3c24473767e4a 595 SUPERFAMILY SSF52518 368 572 2.68E-66 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS06850 b6df91b2c3079a63acd3c24473767e4a 595 Gene3D G3DSA:3.40.50.970 1 192 6.4E-61 T 28-03-2018 CU254_RS06850 b6df91b2c3079a63acd3c24473767e4a 595 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 168 1.1E-56 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CU254_RS06850 b6df91b2c3079a63acd3c24473767e4a 595 SUPERFAMILY SSF52518 2 182 5.54E-62 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS06850 b6df91b2c3079a63acd3c24473767e4a 595 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 4 567 1.8E-232 T 28-03-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CU254_RS06850 b6df91b2c3079a63acd3c24473767e4a 595 Gene3D G3DSA:3.40.50.1220 193 351 8.7E-59 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CU254_RS06850 b6df91b2c3079a63acd3c24473767e4a 595 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 193 328 2.7E-48 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CU254_RS06850 b6df91b2c3079a63acd3c24473767e4a 595 SUPERFAMILY SSF52467 186 358 3.9E-63 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CU254_RS06850 b6df91b2c3079a63acd3c24473767e4a 595 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 391 544 2.0E-48 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CU254_RS06850 b6df91b2c3079a63acd3c24473767e4a 595 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 428 447 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CU254_RS19760 b8bd1fab1a263b7971dc20479bd43e48 258 Gene3D G3DSA:3.40.50.720 3 248 4.6E-27 T 28-03-2018 CU254_RS19760 b8bd1fab1a263b7971dc20479bd43e48 258 Pfam PF13460 NAD(P)H-binding 9 139 1.4E-14 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS19760 b8bd1fab1a263b7971dc20479bd43e48 258 SUPERFAMILY SSF51735 5 220 3.66E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS28935 32b8c37eaefa26094839c6863d1aaad4 103 Gene3D G3DSA:1.10.1660.10 11 101 3.8E-8 T 28-03-2018 CU254_RS28935 32b8c37eaefa26094839c6863d1aaad4 103 Pfam PF13591 MerR HTH family regulatory protein 18 95 4.5E-12 T 28-03-2018 CU254_RS00565 7523a0b580b79ccc4b49727abd3b3263 73 Pfam PF00403 Heavy-metal-associated domain 5 65 3.5E-17 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CU254_RS00565 7523a0b580b79ccc4b49727abd3b3263 73 ProSitePatterns PS01047 Heavy-metal-associated domain. 8 37 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CU254_RS00565 7523a0b580b79ccc4b49727abd3b3263 73 Gene3D G3DSA:3.30.70.100 1 72 5.2E-20 T 28-03-2018 CU254_RS00565 7523a0b580b79ccc4b49727abd3b3263 73 SUPERFAMILY SSF55008 2 67 3.67E-18 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CU254_RS12545 47e278278967ab639847436ae4f97bcb 427 Gene3D G3DSA:1.20.1250.20 19 226 9.3E-18 T 28-03-2018 CU254_RS12545 47e278278967ab639847436ae4f97bcb 427 Gene3D G3DSA:1.20.1250.20 227 425 8.4E-22 T 28-03-2018 CU254_RS12545 47e278278967ab639847436ae4f97bcb 427 SUPERFAMILY SSF103473 20 425 1.96E-59 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS12545 47e278278967ab639847436ae4f97bcb 427 Pfam PF07690 Major Facilitator Superfamily 52 382 4.1E-26 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS22425 25064f79685de74b315e8784b8261446 471 SUPERFAMILY SSF48557 13 463 5.5E-135 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 CU254_RS22425 25064f79685de74b315e8784b8261446 471 TIGRFAM TIGR00838 argH: argininosuccinate lyase 10 459 1.5E-181 T 28-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CU254_RS22425 25064f79685de74b315e8784b8261446 471 Pfam PF00206 Lyase 20 308 4.3E-69 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal CU254_RS22425 25064f79685de74b315e8784b8261446 471 ProSitePatterns PS00163 Fumarate lyases signature. 283 292 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CU254_RS22425 25064f79685de74b315e8784b8261446 471 Gene3D G3DSA:1.10.40.30 383 440 1.2E-25 T 28-03-2018 CU254_RS22425 25064f79685de74b315e8784b8261446 471 PRINTS PR00149 Fumarate lyase superfamily signature 239 266 2.4E-28 T 28-03-2018 IPR000362 Fumarate lyase family CU254_RS22425 25064f79685de74b315e8784b8261446 471 PRINTS PR00149 Fumarate lyase superfamily signature 110 128 2.4E-28 T 28-03-2018 IPR000362 Fumarate lyase family CU254_RS22425 25064f79685de74b315e8784b8261446 471 PRINTS PR00149 Fumarate lyase superfamily signature 155 173 2.4E-28 T 28-03-2018 IPR000362 Fumarate lyase family CU254_RS22425 25064f79685de74b315e8784b8261446 471 PRINTS PR00149 Fumarate lyase superfamily signature 283 299 2.4E-28 T 28-03-2018 IPR000362 Fumarate lyase family CU254_RS22425 25064f79685de74b315e8784b8261446 471 PRINTS PR00145 Argininosuccinate lyase family signature 283 299 2.1E-55 T 28-03-2018 CU254_RS22425 25064f79685de74b315e8784b8261446 471 PRINTS PR00145 Argininosuccinate lyase family signature 150 170 2.1E-55 T 28-03-2018 CU254_RS22425 25064f79685de74b315e8784b8261446 471 PRINTS PR00145 Argininosuccinate lyase family signature 239 263 2.1E-55 T 28-03-2018 CU254_RS22425 25064f79685de74b315e8784b8261446 471 PRINTS PR00145 Argininosuccinate lyase family signature 109 131 2.1E-55 T 28-03-2018 CU254_RS22425 25064f79685de74b315e8784b8261446 471 PRINTS PR00145 Argininosuccinate lyase family signature 318 337 2.1E-55 T 28-03-2018 CU254_RS22425 25064f79685de74b315e8784b8261446 471 PRINTS PR00145 Argininosuccinate lyase family signature 201 217 2.1E-55 T 28-03-2018 CU254_RS22425 25064f79685de74b315e8784b8261446 471 Hamap MF_00006 Argininosuccinate lyase [argH]. 9 461 39.754 T 28-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CU254_RS22425 25064f79685de74b315e8784b8261446 471 Pfam PF14698 Argininosuccinate lyase C-terminal 371 438 4.9E-22 T 28-03-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CU254_RS22425 25064f79685de74b315e8784b8261446 471 Gene3D G3DSA:1.10.275.10 9 114 1.8E-33 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal CU254_RS22425 25064f79685de74b315e8784b8261446 471 Gene3D G3DSA:1.20.200.10 115 382 6.2E-91 T 28-03-2018 CU254_RS34040 1e46cb8c56820b42b57c27a70a8aba93 262 SUPERFAMILY SSF55781 91 259 1.57E-36 T 28-03-2018 IPR029016 GAF domain-like CU254_RS34040 1e46cb8c56820b42b57c27a70a8aba93 262 Pfam PF09339 IclR helix-turn-helix domain 31 65 7.1E-8 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS34040 1e46cb8c56820b42b57c27a70a8aba93 262 Gene3D G3DSA:3.30.450.40 89 262 5.7E-39 T 28-03-2018 IPR029016 GAF domain-like CU254_RS34040 1e46cb8c56820b42b57c27a70a8aba93 262 Gene3D G3DSA:1.10.10.10 6 86 6.9E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS34040 1e46cb8c56820b42b57c27a70a8aba93 262 Pfam PF01614 Bacterial transcriptional regulator 133 257 2.1E-16 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal CU254_RS34040 1e46cb8c56820b42b57c27a70a8aba93 262 SUPERFAMILY SSF46785 17 85 1.48E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS34040 1e46cb8c56820b42b57c27a70a8aba93 262 SMART SM00346 16 106 2.0E-8 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS12360 94833da6ed43b99ab4561624775aa8b5 507 Gene3D G3DSA:1.10.10.60 436 481 5.3E-7 T 28-03-2018 CU254_RS12360 94833da6ed43b99ab4561624775aa8b5 507 Pfam PF07905 Purine catabolism regulatory protein-like family 25 124 1.6E-22 T 28-03-2018 IPR012914 Purine catabolism PurC-like domain CU254_RS12360 94833da6ed43b99ab4561624775aa8b5 507 Gene3D G3DSA:3.20.20.70 5 389 5.9E-4 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS12360 94833da6ed43b99ab4561624775aa8b5 507 Pfam PF13556 PucR C-terminal helix-turn-helix domain 445 502 1.2E-19 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CU254_RS26170 6d6027ce3395428d75041321cd691fab 401 Pfam PF01548 Transposase 9 163 2.6E-42 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CU254_RS26170 6d6027ce3395428d75041321cd691fab 401 Pfam PF02371 Transposase IS116/IS110/IS902 family 272 354 6.9E-23 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CU254_RS41575 5686a7c7c1776eac13b59c5416bb7692 618 SMART SM00944 41 181 1.8E-43 T 28-03-2018 IPR015366 Peptidase S53, activation domain GO:0008236 Reactome: R-HSA-381038 CU254_RS41575 5686a7c7c1776eac13b59c5416bb7692 618 SUPERFAMILY SSF54897 28 191 4.93E-40 T 28-03-2018 IPR009020 Protease propeptides/proteinase inhibitor I9 CU254_RS41575 5686a7c7c1776eac13b59c5416bb7692 618 SUPERFAMILY SSF52743 237 616 4.32E-43 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS41575 5686a7c7c1776eac13b59c5416bb7692 618 Gene3D G3DSA:3.40.50.200 230 618 1.7E-19 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS41575 5686a7c7c1776eac13b59c5416bb7692 618 Pfam PF09286 Pro-kumamolisin, activation domain 45 179 4.9E-27 T 28-03-2018 IPR015366 Peptidase S53, activation domain GO:0008236 Reactome: R-HSA-381038 CU254_RS02680 be84fd297f063874016cdc510f526408 107 SMART SM00418 22 100 1.8E-15 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS02680 be84fd297f063874016cdc510f526408 107 Pfam PF12840 Helix-turn-helix domain 22 79 1.8E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS02680 be84fd297f063874016cdc510f526408 107 SUPERFAMILY SSF46785 9 100 4.05E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS02680 be84fd297f063874016cdc510f526408 107 Gene3D G3DSA:1.10.10.10 8 103 1.5E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS02680 be84fd297f063874016cdc510f526408 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 24 39 3.0E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS02680 be84fd297f063874016cdc510f526408 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 56 71 3.0E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS02680 be84fd297f063874016cdc510f526408 107 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 71 86 3.0E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS04855 20a9458824084579171833ff6bff76aa 160 Pfam PF01668 SmpB protein 10 150 2.6E-64 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 CU254_RS04855 20a9458824084579171833ff6bff76aa 160 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 10 133 3.0E-46 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 CU254_RS04855 20a9458824084579171833ff6bff76aa 160 Gene3D G3DSA:2.40.280.10 10 128 8.7E-54 T 28-03-2018 IPR023620 Small protein B CU254_RS04855 20a9458824084579171833ff6bff76aa 160 SUPERFAMILY SSF74982 3 133 2.88E-55 T 28-03-2018 IPR023620 Small protein B CU254_RS04855 20a9458824084579171833ff6bff76aa 160 Hamap MF_00023 SsrA-binding protein [smpB]. 1 156 77.624 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 CU254_RS04855 20a9458824084579171833ff6bff76aa 160 ProSitePatterns PS01317 SsrA-binding protein. 28 40 - T 28-03-2018 IPR020081 SsrA-binding protein, conserved site CU254_RS04855 20a9458824084579171833ff6bff76aa 160 TIGRFAM TIGR00086 smpB: SsrA-binding protein 9 150 2.0E-61 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 CU254_RS23340 2d166f5fb43902c97a61ee04185d61a4 404 Gene3D G3DSA:3.30.470.20 123 320 1.1E-18 T 28-03-2018 CU254_RS23340 2d166f5fb43902c97a61ee04185d61a4 404 SUPERFAMILY SSF56059 133 306 8.37E-13 T 28-03-2018 CU254_RS16640 10be04ad87cf9bc7b63c2837554209f0 360 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 151 1.3E-22 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CU254_RS16640 10be04ad87cf9bc7b63c2837554209f0 360 Pfam PF00107 Zinc-binding dehydrogenase 195 317 1.8E-23 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CU254_RS16640 10be04ad87cf9bc7b63c2837554209f0 360 SUPERFAMILY SSF50129 309 360 9.42E-8 T 28-03-2018 IPR011032 GroES-like CU254_RS16640 10be04ad87cf9bc7b63c2837554209f0 360 SUPERFAMILY SSF51735 157 324 1.55E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS16640 10be04ad87cf9bc7b63c2837554209f0 360 SMART SM00829 16 358 2.5E-5 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CU254_RS16640 10be04ad87cf9bc7b63c2837554209f0 360 Gene3D G3DSA:3.90.180.10 1 193 5.7E-55 T 28-03-2018 CU254_RS16640 10be04ad87cf9bc7b63c2837554209f0 360 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 60 74 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CU254_RS16640 10be04ad87cf9bc7b63c2837554209f0 360 Gene3D G3DSA:3.40.50.720 194 307 1.4E-22 T 28-03-2018 CU254_RS16640 10be04ad87cf9bc7b63c2837554209f0 360 SUPERFAMILY SSF50129 1 190 3.04E-55 T 28-03-2018 IPR011032 GroES-like CU254_RS14045 74c144841df4be8ead9391b97de26182 411 Gene3D G3DSA:3.30.43.10 1 62 9.7E-11 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CU254_RS14045 74c144841df4be8ead9391b97de26182 411 Pfam PF01565 FAD binding domain 15 142 7.9E-16 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CU254_RS14045 74c144841df4be8ead9391b97de26182 411 SUPERFAMILY SSF56176 3 171 2.59E-27 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CU254_RS14045 74c144841df4be8ead9391b97de26182 411 Gene3D G3DSA:3.30.465.10 63 188 1.5E-16 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CU254_RS14045 74c144841df4be8ead9391b97de26182 411 Pfam PF04030 D-arabinono-1,4-lactone oxidase 283 407 5.0E-11 T 28-03-2018 IPR007173 D-arabinono-1,4-lactone oxidase GO:0003885|GO:0016020|GO:0055114 CU254_RS21750 f41f77033cf48a2b6c19f6da40d5f84d 91 Pfam PF00550 Phosphopantetheine attachment site 5 56 1.7E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS21750 f41f77033cf48a2b6c19f6da40d5f84d 91 SUPERFAMILY SSF47336 4 77 8.51E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS21750 f41f77033cf48a2b6c19f6da40d5f84d 91 Gene3D G3DSA:1.10.1200.10 2 83 1.6E-17 T 28-03-2018 CU254_RS16980 e90ca89895988f9ed233f623d399b1b9 524 Gene3D G3DSA:2.40.10.10 82 265 5.0E-24 T 28-03-2018 CU254_RS16980 e90ca89895988f9ed233f623d399b1b9 524 Pfam PF00089 Trypsin 54 238 2.0E-18 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CU254_RS16980 e90ca89895988f9ed233f623d399b1b9 524 SUPERFAMILY SSF89372 375 509 1.31E-6 T 28-03-2018 CU254_RS16980 e90ca89895988f9ed233f623d399b1b9 524 Gene3D G3DSA:2.115.10.10 355 513 1.8E-8 T 28-03-2018 CU254_RS16980 e90ca89895988f9ed233f623d399b1b9 524 Gene3D G3DSA:2.115.10.10 266 354 0.093 T 28-03-2018 CU254_RS16980 e90ca89895988f9ed233f623d399b1b9 524 SMART SM00020 46 257 1.5E-5 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CU254_RS16980 e90ca89895988f9ed233f623d399b1b9 524 Pfam PF14517 Tachylectin 279 507 5.0E-24 T 28-03-2018 IPR023294 Tachylectin 2 CU254_RS16980 e90ca89895988f9ed233f623d399b1b9 524 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 202 214 1.9E-8 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CU254_RS16980 e90ca89895988f9ed233f623d399b1b9 524 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 73 88 1.9E-8 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CU254_RS16980 e90ca89895988f9ed233f623d399b1b9 524 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 131 145 1.9E-8 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CU254_RS16980 e90ca89895988f9ed233f623d399b1b9 524 Gene3D G3DSA:2.40.10.10 23 81 5.6E-5 T 28-03-2018 CU254_RS16980 e90ca89895988f9ed233f623d399b1b9 524 SUPERFAMILY SSF50494 52 262 3.64E-25 T 28-03-2018 IPR009003 Peptidase S1, PA clan CU254_RS26270 cf9f1fbc25d79f9719b923d003df3c83 357 Pfam PF07508 Recombinase 221 344 1.5E-13 T 28-03-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 CU254_RS26270 cf9f1fbc25d79f9719b923d003df3c83 357 Pfam PF00239 Resolvase, N terminal domain 32 178 5.1E-7 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CU254_RS26270 cf9f1fbc25d79f9719b923d003df3c83 357 Gene3D G3DSA:3.40.50.1390 26 193 6.2E-12 T 28-03-2018 CU254_RS26270 cf9f1fbc25d79f9719b923d003df3c83 357 SUPERFAMILY SSF53041 31 178 1.44E-7 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CU254_RS26270 cf9f1fbc25d79f9719b923d003df3c83 357 SMART SM00857 31 185 2.4E-4 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CU254_RS39040 70418d283f997ad94eef519caa5031f9 558 SUPERFAMILY SSF47831 45 153 6.8E-19 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CU254_RS39040 70418d283f997ad94eef519caa5031f9 558 Pfam PF00391 PEP-utilising enzyme, mobile domain 164 233 6.6E-22 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CU254_RS39040 70418d283f997ad94eef519caa5031f9 558 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 452 467 7.8E-19 T 28-03-2018 CU254_RS39040 70418d283f997ad94eef519caa5031f9 558 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 435 450 7.8E-19 T 28-03-2018 CU254_RS39040 70418d283f997ad94eef519caa5031f9 558 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 291 310 7.8E-19 T 28-03-2018 CU254_RS39040 70418d283f997ad94eef519caa5031f9 558 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 488 500 7.8E-19 T 28-03-2018 CU254_RS39040 70418d283f997ad94eef519caa5031f9 558 Gene3D G3DSA:3.20.20.60 311 531 1.9E-69 T 28-03-2018 CU254_RS39040 70418d283f997ad94eef519caa5031f9 558 SUPERFAMILY SSF52009 135 236 6.15E-27 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CU254_RS39040 70418d283f997ad94eef519caa5031f9 558 Gene3D G3DSA:3.50.30.10 158 275 9.2E-25 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CU254_RS39040 70418d283f997ad94eef519caa5031f9 558 Gene3D G3DSA:3.20.20.60 276 310 3.9E-12 T 28-03-2018 CU254_RS39040 70418d283f997ad94eef519caa5031f9 558 Pfam PF05524 PEP-utilising enzyme, N-terminal 19 136 4.5E-20 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CU254_RS39040 70418d283f997ad94eef519caa5031f9 558 SUPERFAMILY SSF51621 260 536 1.07E-85 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CU254_RS39040 70418d283f997ad94eef519caa5031f9 558 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 261 527 1.5E-78 T 28-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 CU254_RS39040 70418d283f997ad94eef519caa5031f9 558 PIRSF PIRSF000732 13 558 5.7E-148 T 28-03-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 CU254_RS39040 70418d283f997ad94eef519caa5031f9 558 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 58 544 7.0E-106 T 28-03-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 CU254_RS39040 70418d283f997ad94eef519caa5031f9 558 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 435 453 - T 28-03-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 CU254_RS39040 70418d283f997ad94eef519caa5031f9 558 Gene3D G3DSA:1.10.274.10 42 155 2.2E-21 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CU254_RS39040 70418d283f997ad94eef519caa5031f9 558 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 194 205 - T 28-03-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 CU254_RS22455 ad4d17e1f439ffc64f38092a56d8ccd9 386 Pfam PF01960 ArgJ family 11 386 3.8E-127 T 28-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CU254_RS22455 ad4d17e1f439ffc64f38092a56d8ccd9 386 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 386 132.497 T 28-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CU254_RS22455 ad4d17e1f439ffc64f38092a56d8ccd9 386 SUPERFAMILY SSF56266 6 382 3.01E-123 T 28-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CU254_RS22455 ad4d17e1f439ffc64f38092a56d8ccd9 386 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 2 385 1.2E-109 T 28-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CU254_RS22455 ad4d17e1f439ffc64f38092a56d8ccd9 386 Gene3D G3DSA:3.60.70.12 1 262 4.7E-90 T 28-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CU254_RS22455 ad4d17e1f439ffc64f38092a56d8ccd9 386 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 17 384 5.0E-116 T 28-03-2018 CU254_RS27730 6e66d98685f0b5a9628846ea577a329a 499 Pfam PF00501 AMP-binding enzyme 19 403 4.2E-94 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS27730 6e66d98685f0b5a9628846ea577a329a 499 Gene3D G3DSA:3.40.50.980 161 313 2.0E-45 T 28-03-2018 CU254_RS27730 6e66d98685f0b5a9628846ea577a329a 499 Gene3D G3DSA:3.40.50.980 5 160 2.3E-38 T 28-03-2018 CU254_RS27730 6e66d98685f0b5a9628846ea577a329a 499 ProSitePatterns PS00455 Putative AMP-binding domain signature. 155 166 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS27730 6e66d98685f0b5a9628846ea577a329a 499 Gene3D G3DSA:3.30.300.30 398 498 2.4E-27 T 28-03-2018 CU254_RS27730 6e66d98685f0b5a9628846ea577a329a 499 SUPERFAMILY SSF56801 14 496 1.57E-140 T 28-03-2018 CU254_RS27730 6e66d98685f0b5a9628846ea577a329a 499 Gene3D G3DSA:2.30.38.10 314 397 7.9E-27 T 28-03-2018 CU254_RS27730 6e66d98685f0b5a9628846ea577a329a 499 Pfam PF13193 AMP-binding enzyme C-terminal domain 413 488 9.4E-19 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS28010 5585479b7ebacf3414d4fcf97900b624 245 Gene3D G3DSA:3.40.50.720 1 233 5.6E-56 T 28-03-2018 CU254_RS28010 5585479b7ebacf3414d4fcf97900b624 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 8.2E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS28010 5585479b7ebacf3414d4fcf97900b624 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 8.2E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS28010 5585479b7ebacf3414d4fcf97900b624 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 8.2E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS28010 5585479b7ebacf3414d4fcf97900b624 245 Pfam PF00106 short chain dehydrogenase 4 191 4.1E-50 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS28010 5585479b7ebacf3414d4fcf97900b624 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 5.5E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS28010 5585479b7ebacf3414d4fcf97900b624 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 5.5E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS28010 5585479b7ebacf3414d4fcf97900b624 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 5.5E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS28010 5585479b7ebacf3414d4fcf97900b624 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 5.5E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS28010 5585479b7ebacf3414d4fcf97900b624 245 SUPERFAMILY SSF51735 1 234 2.11E-61 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS28010 5585479b7ebacf3414d4fcf97900b624 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS19845 e5a2e8a0d6a284a801e0bd4998404a06 214 SUPERFAMILY SSF161111 27 209 7.06E-30 T 28-03-2018 CU254_RS19845 e5a2e8a0d6a284a801e0bd4998404a06 214 Pfam PF01545 Cation efflux family 39 205 2.3E-11 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CU254_RS19845 e5a2e8a0d6a284a801e0bd4998404a06 214 Gene3D G3DSA:1.20.1510.10 24 210 6.9E-20 T 28-03-2018 CU254_RS28095 cb9a28198aabfe2eb23c97e0a499d21e 61 Pfam PF17227 Family of unknown function (DUF5302) 12 61 9.5E-20 T 28-03-2018 IPR035172 Protein of unknown function DUF5302 CU254_RS09290 01f6612d0981fc7132cdc4fced2e2082 169 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 5 154 1.3E-18 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS09290 01f6612d0981fc7132cdc4fced2e2082 169 Pfam PF08281 Sigma-70, region 4 100 152 1.8E-14 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS09290 01f6612d0981fc7132cdc4fced2e2082 169 SUPERFAMILY SSF88659 95 155 7.1E-15 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS09290 01f6612d0981fc7132cdc4fced2e2082 169 Gene3D G3DSA:1.10.1740.10 2 68 2.2E-12 T 28-03-2018 CU254_RS09290 01f6612d0981fc7132cdc4fced2e2082 169 Gene3D G3DSA:1.10.10.10 69 158 3.1E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS09290 01f6612d0981fc7132cdc4fced2e2082 169 SUPERFAMILY SSF88946 5 87 1.02E-12 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS09290 01f6612d0981fc7132cdc4fced2e2082 169 Pfam PF04542 Sigma-70 region 2 11 72 1.9E-8 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS12995 b4872ed51ff8be9da198c884d50f4d4e 425 TIGRFAM TIGR03494 salicyl_syn: salicylate synthase 16 423 3.5E-149 T 28-03-2018 IPR019996 Salicylate synthase GO:0008909|GO:0016833 KEGG: 00130+5.4.4.2|KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6120|MetaCyc: PWY-6406|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CU254_RS12995 b4872ed51ff8be9da198c884d50f4d4e 425 SUPERFAMILY SSF56322 7 420 7.2E-87 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CU254_RS12995 b4872ed51ff8be9da198c884d50f4d4e 425 Pfam PF00425 chorismate binding enzyme 162 414 1.1E-68 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal CU254_RS12995 b4872ed51ff8be9da198c884d50f4d4e 425 Gene3D G3DSA:3.60.120.10 3 423 1.3E-82 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CU254_RS01785 40eea88267e7eaa3838cf9d1b9c37852 328 Pfam PF02470 MlaD protein 39 112 3.1E-15 T 28-03-2018 IPR003399 Mce/MlaD CU254_RS01785 40eea88267e7eaa3838cf9d1b9c37852 328 Gene3D G3DSA:1.20.120.570 133 298 7.6E-8 T 28-03-2018 CU254_RS01785 40eea88267e7eaa3838cf9d1b9c37852 328 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 12 291 1.3E-58 T 28-03-2018 IPR005693 Virulence factor Mce protein CU254_RS01785 40eea88267e7eaa3838cf9d1b9c37852 328 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 28 48 7.4E-15 T 28-03-2018 IPR005693 Virulence factor Mce protein CU254_RS01785 40eea88267e7eaa3838cf9d1b9c37852 328 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 246 265 7.4E-15 T 28-03-2018 IPR005693 Virulence factor Mce protein CU254_RS01785 40eea88267e7eaa3838cf9d1b9c37852 328 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 128 152 7.4E-15 T 28-03-2018 IPR005693 Virulence factor Mce protein CU254_RS01785 40eea88267e7eaa3838cf9d1b9c37852 328 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 177 195 7.4E-15 T 28-03-2018 IPR005693 Virulence factor Mce protein CU254_RS01785 40eea88267e7eaa3838cf9d1b9c37852 328 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 297 316 7.4E-15 T 28-03-2018 IPR005693 Virulence factor Mce protein CU254_RS01785 40eea88267e7eaa3838cf9d1b9c37852 328 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 90 106 7.4E-15 T 28-03-2018 IPR005693 Virulence factor Mce protein CU254_RS36685 9502aafb0ecf5c4af61a3d2c71a16423 541 TIGRFAM TIGR01686 FkbH: FkbH domain 199 516 9.1E-90 T 28-03-2018 IPR010037 FkbH domain CU254_RS36685 9502aafb0ecf5c4af61a3d2c71a16423 541 SUPERFAMILY SSF56784 197 316 6.97E-11 T 28-03-2018 IPR023214 HAD-like domain CU254_RS36685 9502aafb0ecf5c4af61a3d2c71a16423 541 Gene3D G3DSA:3.40.50.1000 197 358 4.2E-15 T 28-03-2018 IPR023214 HAD-like domain CU254_RS36685 9502aafb0ecf5c4af61a3d2c71a16423 541 TIGRFAM TIGR01681 HAD-SF-IIIC: HAD phosphatase, family IIIC 200 316 5.3E-18 T 28-03-2018 IPR010033 HAD-superfamily phosphatase, subfamily IIIC CU254_RS13355 e4cf7ddf522459664c9ed61b2243f0de 537 Gene3D G3DSA:3.40.50.980 38 199 9.4E-34 T 28-03-2018 CU254_RS13355 e4cf7ddf522459664c9ed61b2243f0de 537 ProSitePatterns PS00455 Putative AMP-binding domain signature. 194 205 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS13355 e4cf7ddf522459664c9ed61b2243f0de 537 Gene3D G3DSA:2.30.38.10 350 428 3.7E-17 T 28-03-2018 CU254_RS13355 e4cf7ddf522459664c9ed61b2243f0de 537 Pfam PF00501 AMP-binding enzyme 50 435 3.5E-79 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS13355 e4cf7ddf522459664c9ed61b2243f0de 537 Gene3D G3DSA:3.30.300.30 429 537 1.1E-27 T 28-03-2018 CU254_RS13355 e4cf7ddf522459664c9ed61b2243f0de 537 Pfam PF13193 AMP-binding enzyme C-terminal domain 444 522 2.1E-20 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS13355 e4cf7ddf522459664c9ed61b2243f0de 537 Gene3D G3DSA:3.40.50.980 200 349 1.2E-37 T 28-03-2018 CU254_RS13355 e4cf7ddf522459664c9ed61b2243f0de 537 SUPERFAMILY SSF56801 28 534 9.55E-133 T 28-03-2018 CU254_RS42200 d18d19d68abfa9f1308197ed57a4a5c7 1190 Gene3D G3DSA:3.20.20.140 2 274 5.8E-46 T 28-03-2018 CU254_RS42200 d18d19d68abfa9f1308197ed57a4a5c7 1190 SUPERFAMILY SSF89550 5 90 1.14E-26 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CU254_RS42200 d18d19d68abfa9f1308197ed57a4a5c7 1190 SUPERFAMILY SSF89550 126 253 1.14E-26 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CU254_RS42200 d18d19d68abfa9f1308197ed57a4a5c7 1190 Pfam PF02811 PHP domain 7 199 1.8E-45 T 28-03-2018 IPR004013 PHP domain GO:0003824 CU254_RS42200 d18d19d68abfa9f1308197ed57a4a5c7 1190 SMART SM00481 6 73 1.9E-30 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CU254_RS42200 d18d19d68abfa9f1308197ed57a4a5c7 1190 Gene3D G3DSA:2.40.50.140 1006 1102 5.8E-11 T 28-03-2018 CU254_RS42200 d18d19d68abfa9f1308197ed57a4a5c7 1190 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 321 760 2.5E-157 T 28-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CU254_RS42200 d18d19d68abfa9f1308197ed57a4a5c7 1190 Gene3D G3DSA:1.10.150.280 814 919 3.2E-5 T 28-03-2018 CU254_RS42200 d18d19d68abfa9f1308197ed57a4a5c7 1190 Pfam PF14579 Helix-hairpin-helix motif 835 921 2.1E-23 T 28-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CU254_RS42200 d18d19d68abfa9f1308197ed57a4a5c7 1190 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 5 1065 0.0 T 28-03-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CU254_RS02860 b1b61d815eb579cf7df778945c85f46e 402 SUPERFAMILY SSF103473 11 393 2.09E-58 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS02860 b1b61d815eb579cf7df778945c85f46e 402 Pfam PF07690 Major Facilitator Superfamily 37 363 2.7E-40 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS02860 b1b61d815eb579cf7df778945c85f46e 402 Gene3D G3DSA:1.20.1250.20 213 402 1.9E-23 T 28-03-2018 CU254_RS02860 b1b61d815eb579cf7df778945c85f46e 402 Gene3D G3DSA:1.20.1250.20 9 211 4.5E-27 T 28-03-2018 CU254_RS24660 b66a78bdb349f82a232bc3e68a59eae0 323 PIRSF PIRSF002849 2 320 9.4E-131 T 28-03-2018 CU254_RS24660 b66a78bdb349f82a232bc3e68a59eae0 323 Gene3D G3DSA:1.10.8.300 207 315 2.0E-32 T 28-03-2018 CU254_RS24660 b66a78bdb349f82a232bc3e68a59eae0 323 SUPERFAMILY SSF52540 15 290 4.83E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS24660 b66a78bdb349f82a232bc3e68a59eae0 323 Gene3D G3DSA:3.40.50.300 27 193 9.3E-26 T 28-03-2018 CU254_RS24660 b66a78bdb349f82a232bc3e68a59eae0 323 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 46 175 1.1E-62 T 28-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 CU254_RS20870 0afc9e2bd051eb4889c16a5eb3812006 386 Pfam PF03747 ADP-ribosylglycohydrolase 11 337 2.8E-45 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 CU254_RS20870 0afc9e2bd051eb4889c16a5eb3812006 386 Gene3D G3DSA:1.10.4080.10 2 376 1.7E-56 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 CU254_RS20870 0afc9e2bd051eb4889c16a5eb3812006 386 SUPERFAMILY SSF101478 3 239 1.57E-41 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 CU254_RS20870 0afc9e2bd051eb4889c16a5eb3812006 386 SUPERFAMILY SSF101478 278 346 1.57E-41 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 CU254_RS04450 5201acb4de3344f7de0ac304ea7545e6 779 Hamap MF_01382 Protein translocase subunit SecA [secA]. 10 732 15.47 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CU254_RS04450 5201acb4de3344f7de0ac304ea7545e6 779 Gene3D G3DSA:1.10.3060.10 584 740 3.6E-20 T 28-03-2018 CU254_RS04450 5201acb4de3344f7de0ac304ea7545e6 779 SMART SM00957 11 389 4.0E-143 T 28-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CU254_RS04450 5201acb4de3344f7de0ac304ea7545e6 779 ProSitePatterns PS01312 SecA family signature. 487 502 - T 28-03-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 CU254_RS04450 5201acb4de3344f7de0ac304ea7545e6 779 SUPERFAMILY SSF52540 12 234 9.24E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS04450 5201acb4de3344f7de0ac304ea7545e6 779 SUPERFAMILY SSF52540 355 402 9.24E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS04450 5201acb4de3344f7de0ac304ea7545e6 779 Gene3D G3DSA:3.40.50.300 404 503 2.1E-20 T 28-03-2018 CU254_RS04450 5201acb4de3344f7de0ac304ea7545e6 779 Gene3D G3DSA:3.40.50.300 506 577 7.0E-13 T 28-03-2018 CU254_RS04450 5201acb4de3344f7de0ac304ea7545e6 779 Gene3D G3DSA:3.90.1440.10 245 355 1.8E-29 T 28-03-2018 CU254_RS04450 5201acb4de3344f7de0ac304ea7545e6 779 SMART SM00958 233 345 1.1E-28 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CU254_RS04450 5201acb4de3344f7de0ac304ea7545e6 779 Pfam PF07516 SecA Wing and Scaffold domain 638 726 3.0E-11 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CU254_RS04450 5201acb4de3344f7de0ac304ea7545e6 779 SUPERFAMILY SSF81886 584 734 9.16E-25 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CU254_RS04450 5201acb4de3344f7de0ac304ea7545e6 779 TIGRFAM TIGR04221 SecA2_Mycobac: accessory Sec system translocase SecA2 10 775 0.0 T 28-03-2018 IPR026389 Protein translocase subunit SecA, Actinobacteria-type CU254_RS04450 5201acb4de3344f7de0ac304ea7545e6 779 Pfam PF01043 SecA preprotein cross-linking domain 242 345 4.5E-21 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CU254_RS04450 5201acb4de3344f7de0ac304ea7545e6 779 SUPERFAMILY SSF81767 243 353 1.05E-29 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CU254_RS04450 5201acb4de3344f7de0ac304ea7545e6 779 Gene3D G3DSA:3.40.50.300 73 244 3.2E-9 T 28-03-2018 CU254_RS04450 5201acb4de3344f7de0ac304ea7545e6 779 Pfam PF07517 SecA DEAD-like domain 13 388 2.7E-88 T 28-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CU254_RS04450 5201acb4de3344f7de0ac304ea7545e6 779 PRINTS PR00906 SecA protein signature 326 348 1.3E-37 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CU254_RS04450 5201acb4de3344f7de0ac304ea7545e6 779 PRINTS PR00906 SecA protein signature 400 413 1.3E-37 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CU254_RS04450 5201acb4de3344f7de0ac304ea7545e6 779 PRINTS PR00906 SecA protein signature 176 196 1.3E-37 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CU254_RS04450 5201acb4de3344f7de0ac304ea7545e6 779 PRINTS PR00906 SecA protein signature 123 133 1.3E-37 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CU254_RS04450 5201acb4de3344f7de0ac304ea7545e6 779 PRINTS PR00906 SecA protein signature 363 380 1.3E-37 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CU254_RS04450 5201acb4de3344f7de0ac304ea7545e6 779 PRINTS PR00906 SecA protein signature 107 121 1.3E-37 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CU254_RS04450 5201acb4de3344f7de0ac304ea7545e6 779 PRINTS PR00906 SecA protein signature 69 93 1.3E-37 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CU254_RS04450 5201acb4de3344f7de0ac304ea7545e6 779 SUPERFAMILY SSF52540 404 564 1.66E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS22140 36370bb00ced02d65ee79a2d40ab1c05 384 Pfam PF05762 VWA domain containing CoxE-like protein 145 363 6.5E-53 T 28-03-2018 IPR008912 Uncharacterised protein family CoxE-like CU254_RS22140 36370bb00ced02d65ee79a2d40ab1c05 384 Gene3D G3DSA:3.40.50.410 167 349 1.2E-12 T 28-03-2018 IPR002035 von Willebrand factor, type A CU254_RS22140 36370bb00ced02d65ee79a2d40ab1c05 384 SUPERFAMILY SSF53300 206 368 6.04E-24 T 28-03-2018 IPR002035 von Willebrand factor, type A CU254_RS32260 632fd6e72cd633807324d1d288c7a212 297 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 33 290 7.0E-40 T 28-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 CU254_RS32260 632fd6e72cd633807324d1d288c7a212 297 SUPERFAMILY SSF53850 33 294 6.51E-43 T 28-03-2018 CU254_RS32260 632fd6e72cd633807324d1d288c7a212 297 Gene3D G3DSA:3.40.190.10 22 174 1.4E-23 T 28-03-2018 CU254_RS32260 632fd6e72cd633807324d1d288c7a212 297 Gene3D G3DSA:3.40.190.10 175 295 3.4E-18 T 28-03-2018 CU254_RS35880 2750add90655a61427343f2338f9dd35 318 SUPERFAMILY SSF54292 212 317 1.23E-22 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CU254_RS35880 2750add90655a61427343f2338f9dd35 318 Gene3D G3DSA:2.40.30.10 3 97 2.9E-12 T 28-03-2018 CU254_RS35880 2750add90655a61427343f2338f9dd35 318 SUPERFAMILY SSF63380 6 93 1.06E-20 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CU254_RS35880 2750add90655a61427343f2338f9dd35 318 Gene3D G3DSA:3.10.20.30 220 318 3.4E-17 T 28-03-2018 IPR012675 Beta-grasp domain CU254_RS35880 2750add90655a61427343f2338f9dd35 318 SUPERFAMILY SSF52343 104 227 5.76E-26 T 28-03-2018 CU254_RS35880 2750add90655a61427343f2338f9dd35 318 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 239 308 7.1E-9 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CU254_RS35880 2750add90655a61427343f2338f9dd35 318 Pfam PF00175 Oxidoreductase NAD-binding domain 110 202 3.9E-5 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CU254_RS35880 2750add90655a61427343f2338f9dd35 318 Gene3D G3DSA:3.40.50.80 101 219 8.1E-19 T 28-03-2018 CU254_RS35880 2750add90655a61427343f2338f9dd35 318 PRINTS PR00409 Phthalate dioxygenase reductase family signature 74 88 2.2E-29 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CU254_RS35880 2750add90655a61427343f2338f9dd35 318 PRINTS PR00409 Phthalate dioxygenase reductase family signature 189 197 2.2E-29 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CU254_RS35880 2750add90655a61427343f2338f9dd35 318 PRINTS PR00409 Phthalate dioxygenase reductase family signature 28 38 2.2E-29 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CU254_RS35880 2750add90655a61427343f2338f9dd35 318 PRINTS PR00409 Phthalate dioxygenase reductase family signature 109 128 2.2E-29 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CU254_RS35880 2750add90655a61427343f2338f9dd35 318 PRINTS PR00409 Phthalate dioxygenase reductase family signature 134 143 2.2E-29 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CU254_RS35880 2750add90655a61427343f2338f9dd35 318 PRINTS PR00409 Phthalate dioxygenase reductase family signature 38 50 2.2E-29 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CU254_RS35880 2750add90655a61427343f2338f9dd35 318 PRINTS PR00409 Phthalate dioxygenase reductase family signature 50 64 2.2E-29 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CU254_RS35880 2750add90655a61427343f2338f9dd35 318 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 266 274 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CU254_RS17940 f2f5ab77774f2be0ecd38ca6fb9f8719 254 TIGRFAM TIGR03442 TIGR03442: ergothioneine biosynthesis protein EgtC 1 245 1.2E-80 T 28-03-2018 IPR017808 Ergothioneine biosynthesis protein EgtC GO:0052699 CU254_RS17940 f2f5ab77774f2be0ecd38ca6fb9f8719 254 SUPERFAMILY SSF56235 23 243 1.05E-17 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CU254_RS17940 f2f5ab77774f2be0ecd38ca6fb9f8719 254 Pfam PF13522 Glutamine amidotransferase domain 77 217 1.0E-14 T 28-03-2018 CU254_RS17940 f2f5ab77774f2be0ecd38ca6fb9f8719 254 Gene3D G3DSA:3.60.20.10 1 211 8.7E-28 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CU254_RS17940 f2f5ab77774f2be0ecd38ca6fb9f8719 254 Hamap MF_02036 Gamma-glutamyl-hercynylcysteine sulfoxide hydrolase [egtC]. 1 246 38.911 T 28-03-2018 IPR032889 Gamma-glutamyl-hercynylcysteine sulfoxide hydrolase, Actinobacteria GO:0016811|GO:0052699 CU254_RS40370 2e4361c6e0866f283a0f9cfd5b46cdd4 251 SUPERFAMILY SSF51735 11 248 3.27E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS40370 2e4361c6e0866f283a0f9cfd5b46cdd4 251 Gene3D G3DSA:3.40.50.720 6 249 2.1E-34 T 28-03-2018 CU254_RS40370 2e4361c6e0866f283a0f9cfd5b46cdd4 251 Pfam PF00106 short chain dehydrogenase 12 198 3.1E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS40370 2e4361c6e0866f283a0f9cfd5b46cdd4 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 3.3E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS40370 2e4361c6e0866f283a0f9cfd5b46cdd4 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 3.3E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS40370 2e4361c6e0866f283a0f9cfd5b46cdd4 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 3.3E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS40370 2e4361c6e0866f283a0f9cfd5b46cdd4 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 3.3E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS40370 2e4361c6e0866f283a0f9cfd5b46cdd4 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 3.3E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS08360 6b30772710564b5e48b563e48c72bd17 869 SMART SM00060 671 754 0.0011 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CU254_RS08360 6b30772710564b5e48b563e48c72bd17 869 SMART SM00060 773 859 4.5E-8 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CU254_RS08360 6b30772710564b5e48b563e48c72bd17 869 Gene3D G3DSA:2.160.20.10 61 670 1.6E-31 T 28-03-2018 IPR012334 Pectin lyase fold CU254_RS08360 6b30772710564b5e48b563e48c72bd17 869 SUPERFAMILY SSF49265 683 865 1.67E-21 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CU254_RS08360 6b30772710564b5e48b563e48c72bd17 869 Gene3D G3DSA:2.60.40.10 776 869 2.7E-12 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS08360 6b30772710564b5e48b563e48c72bd17 869 SMART SM00710 391 413 8300.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CU254_RS08360 6b30772710564b5e48b563e48c72bd17 869 SMART SM00710 515 542 380.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CU254_RS08360 6b30772710564b5e48b563e48c72bd17 869 SMART SM00710 321 356 3400.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CU254_RS08360 6b30772710564b5e48b563e48c72bd17 869 SMART SM00710 449 474 4600.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CU254_RS08360 6b30772710564b5e48b563e48c72bd17 869 SMART SM00710 477 498 320.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CU254_RS08360 6b30772710564b5e48b563e48c72bd17 869 SMART SM00710 415 437 250.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CU254_RS08360 6b30772710564b5e48b563e48c72bd17 869 Pfam PF13229 Right handed beta helix region 386 584 1.5E-6 T 28-03-2018 CU254_RS08360 6b30772710564b5e48b563e48c72bd17 869 Gene3D G3DSA:2.60.40.10 671 766 4.2E-11 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS08360 6b30772710564b5e48b563e48c72bd17 869 Pfam PF00041 Fibronectin type III domain 779 860 7.9E-12 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CU254_RS08360 6b30772710564b5e48b563e48c72bd17 869 SUPERFAMILY SSF51126 21 124 4.37E-31 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor CU254_RS08360 6b30772710564b5e48b563e48c72bd17 869 SUPERFAMILY SSF51126 311 335 4.37E-31 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor CU254_RS08360 6b30772710564b5e48b563e48c72bd17 869 SUPERFAMILY SSF51126 383 635 4.37E-31 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor CU254_RS29630 2cc872da33fcd148f569dcd6697d8f20 251 Gene3D G3DSA:3.40.50.720 1 251 9.6E-52 T 28-03-2018 CU254_RS29630 2cc872da33fcd148f569dcd6697d8f20 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 4.9E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS29630 2cc872da33fcd148f569dcd6697d8f20 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 4.9E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS29630 2cc872da33fcd148f569dcd6697d8f20 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 4.9E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS29630 2cc872da33fcd148f569dcd6697d8f20 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 1.9E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS29630 2cc872da33fcd148f569dcd6697d8f20 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 1.9E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS29630 2cc872da33fcd148f569dcd6697d8f20 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 1.9E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS29630 2cc872da33fcd148f569dcd6697d8f20 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 1.9E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS29630 2cc872da33fcd148f569dcd6697d8f20 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 1.9E-17 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS29630 2cc872da33fcd148f569dcd6697d8f20 251 SUPERFAMILY SSF51735 7 250 3.64E-54 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS29630 2cc872da33fcd148f569dcd6697d8f20 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 249 1.4E-44 T 28-03-2018 CU254_RS09130 c85b7fa81cec5b8c4b887202f79cccc8 226 SUPERFAMILY SSF54909 32 129 8.05E-17 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS09130 c85b7fa81cec5b8c4b887202f79cccc8 226 Pfam PF07978 NIPSNAP 33 128 1.6E-13 T 28-03-2018 IPR012577 NIPSNAP CU254_RS09130 c85b7fa81cec5b8c4b887202f79cccc8 226 Gene3D G3DSA:3.30.70.100 28 135 1.9E-20 T 28-03-2018 CU254_RS35290 7968658306b4f1ba6fa26c09363e9988 1019 SMART SM00387 542 655 1.9E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS35290 7968658306b4f1ba6fa26c09363e9988 1019 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 546 653 1.1E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS35290 7968658306b4f1ba6fa26c09363e9988 1019 Pfam PF08376 Nitrate and nitrite sensing 83 320 6.8E-30 T 28-03-2018 IPR013587 Nitrate/nitrite sensing protein CU254_RS35290 7968658306b4f1ba6fa26c09363e9988 1019 Pfam PF00672 HAMP domain 358 426 6.4E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS35290 7968658306b4f1ba6fa26c09363e9988 1019 Gene3D G3DSA:3.30.565.10 463 654 6.4E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS35290 7968658306b4f1ba6fa26c09363e9988 1019 SUPERFAMILY SSF55874 529 652 1.14E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS35290 7968658306b4f1ba6fa26c09363e9988 1019 SMART SM00304 358 430 0.0013 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS00090 a84f708939fa279fad431ee07681d195 320 SUPERFAMILY SSF53474 47 318 3.56E-73 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS00090 a84f708939fa279fad431ee07681d195 320 Pfam PF07859 alpha/beta hydrolase fold 84 292 6.5E-72 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CU254_RS00090 a84f708939fa279fad431ee07681d195 320 Gene3D G3DSA:3.40.50.1820 2 320 6.2E-64 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS01595 da310de6b3dc6f0990ac75a57f861e5c 290 Gene3D G3DSA:3.20.20.30 1 249 8.5E-59 T 28-03-2018 CU254_RS01595 da310de6b3dc6f0990ac75a57f861e5c 290 TIGRFAM TIGR03560 F420_Rv1855c: probable F420-dependent oxidoreductase, Rv1855c family 13 232 3.9E-89 T 28-03-2018 IPR019952 F420-dependent oxidoreductase-predicted, Rv1855c CU254_RS01595 da310de6b3dc6f0990ac75a57f861e5c 290 Gene3D G3DSA:3.20.20.30 250 289 0.052 T 28-03-2018 CU254_RS01595 da310de6b3dc6f0990ac75a57f861e5c 290 Pfam PF00296 Luciferase-like monooxygenase 2 243 3.8E-48 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS01595 da310de6b3dc6f0990ac75a57f861e5c 290 SUPERFAMILY SSF51679 1 287 3.39E-64 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS01595 da310de6b3dc6f0990ac75a57f861e5c 290 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 25 262 5.1E-50 T 28-03-2018 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted CU254_RS13445 4018d1a47e5bf0e7cd676d76a4888170 668 Gene3D G3DSA:3.20.20.80 2 369 2.1E-89 T 28-03-2018 CU254_RS13445 4018d1a47e5bf0e7cd676d76a4888170 668 SUPERFAMILY SSF52317 387 594 3.36E-60 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS13445 4018d1a47e5bf0e7cd676d76a4888170 668 Pfam PF08533 Beta-galactosidase C-terminal domain 610 660 6.4E-9 T 28-03-2018 IPR013739 Beta-galactosidase C-terminal GO:0004565|GO:0006012 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CU254_RS13445 4018d1a47e5bf0e7cd676d76a4888170 668 SUPERFAMILY SSF51445 4 361 1.79E-114 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS13445 4018d1a47e5bf0e7cd676d76a4888170 668 Gene3D G3DSA:3.40.50.880 387 598 1.6E-70 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS13445 4018d1a47e5bf0e7cd676d76a4888170 668 PIRSF PIRSF001084 1 662 3.3E-264 T 28-03-2018 IPR003476 Glycoside hydrolase, family 42 GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CU254_RS13445 4018d1a47e5bf0e7cd676d76a4888170 668 Pfam PF02449 Beta-galactosidase 9 379 2.1E-148 T 28-03-2018 IPR013529 Glycoside hydrolase, family 42, N-terminal GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CU254_RS13445 4018d1a47e5bf0e7cd676d76a4888170 668 Gene3D G3DSA:2.60.40.1180 602 660 2.9E-14 T 28-03-2018 CU254_RS13445 4018d1a47e5bf0e7cd676d76a4888170 668 Pfam PF08532 Beta-galactosidase trimerisation domain 390 594 2.1E-62 T 28-03-2018 IPR013738 Beta-galactosidase trimerisation GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CU254_RS01280 072e9bb710818540fe1e9b5d45f37c4a 560 SUPERFAMILY SSF52518 9 183 2.26E-33 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS01280 072e9bb710818540fe1e9b5d45f37c4a 560 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 10 180 2.3E-32 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CU254_RS01280 072e9bb710818540fe1e9b5d45f37c4a 560 Hamap MF_01659 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [menD]. 3 553 32.274 T 28-03-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 CU254_RS01280 072e9bb710818540fe1e9b5d45f37c4a 560 SUPERFAMILY SSF52518 368 545 2.12E-23 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS01280 072e9bb710818540fe1e9b5d45f37c4a 560 Gene3D G3DSA:3.40.50.1220 219 349 2.4E-10 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CU254_RS01280 072e9bb710818540fe1e9b5d45f37c4a 560 Gene3D G3DSA:3.40.50.970 3 196 5.2E-55 T 28-03-2018 CU254_RS01280 072e9bb710818540fe1e9b5d45f37c4a 560 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 410 527 4.9E-7 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CU254_RS01280 072e9bb710818540fe1e9b5d45f37c4a 560 Gene3D G3DSA:3.40.50.970 350 556 1.5E-27 T 28-03-2018 CU254_RS01280 072e9bb710818540fe1e9b5d45f37c4a 560 PIRSF PIRSF004983 3 559 6.6E-141 T 28-03-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 CU254_RS01280 072e9bb710818540fe1e9b5d45f37c4a 560 TIGRFAM TIGR00173 menD: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase 9 428 1.5E-114 T 28-03-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 CU254_RS11245 a50f08aec02dbe55fb85ec3a109d9ca4 412 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 235 272 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CU254_RS11245 a50f08aec02dbe55fb85ec3a109d9ca4 412 SUPERFAMILY SSF53383 15 410 1.97E-118 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS11245 a50f08aec02dbe55fb85ec3a109d9ca4 412 TIGRFAM TIGR01885 Orn_aminotrans: ornithine--oxo-acid transaminase 19 410 1.7E-143 T 28-03-2018 IPR010164 Ornithine aminotransferase GO:0004587 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CU254_RS11245 a50f08aec02dbe55fb85ec3a109d9ca4 412 Pfam PF00202 Aminotransferase class-III 29 409 1.3E-112 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CU254_RS11245 a50f08aec02dbe55fb85ec3a109d9ca4 412 Gene3D G3DSA:3.40.640.10 193 306 2.2E-42 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS11245 a50f08aec02dbe55fb85ec3a109d9ca4 412 PIRSF PIRSF000521 4 184 4.9E-6 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CU254_RS11245 a50f08aec02dbe55fb85ec3a109d9ca4 412 PIRSF PIRSF000521 186 412 4.0E-29 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CU254_RS11245 a50f08aec02dbe55fb85ec3a109d9ca4 412 Gene3D G3DSA:3.90.1150.10 307 412 2.7E-21 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS11245 a50f08aec02dbe55fb85ec3a109d9ca4 412 Gene3D G3DSA:3.90.1150.10 13 192 4.6E-40 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS03845 2cca5b26308be9fa959fb21d8332b437 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 272 1.6E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS03845 2cca5b26308be9fa959fb21d8332b437 280 SUPERFAMILY SSF161098 12 280 5.89E-74 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS03845 2cca5b26308be9fa959fb21d8332b437 280 Gene3D G3DSA:1.10.3720.10 16 271 2.9E-46 T 28-03-2018 CU254_RS17775 5f8e8a079407ad7a7cc7b7d3faa1e99b 378 Pfam PF00534 Glycosyl transferases group 1 200 346 4.8E-22 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CU254_RS17775 5f8e8a079407ad7a7cc7b7d3faa1e99b 378 SUPERFAMILY SSF53756 5 371 1.2E-72 T 28-03-2018 CU254_RS17775 5f8e8a079407ad7a7cc7b7d3faa1e99b 378 Gene3D G3DSA:3.40.50.2000 1 194 1.1E-20 T 28-03-2018 CU254_RS17775 5f8e8a079407ad7a7cc7b7d3faa1e99b 378 Pfam PF13439 Glycosyltransferase Family 4 17 187 2.9E-21 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CU254_RS17775 5f8e8a079407ad7a7cc7b7d3faa1e99b 378 Gene3D G3DSA:3.40.50.2000 195 352 1.9E-37 T 28-03-2018 CU254_RS31960 a25c086b7612a6ec8f6f5cd753bed51c 460 Pfam PF01425 Amidase 24 445 9.1E-102 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS31960 a25c086b7612a6ec8f6f5cd753bed51c 460 SUPERFAMILY SSF75304 5 454 1.05E-135 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS31960 a25c086b7612a6ec8f6f5cd753bed51c 460 Gene3D G3DSA:3.90.1300.10 4 460 3.8E-140 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS31960 a25c086b7612a6ec8f6f5cd753bed51c 460 ProSitePatterns PS00571 Amidases signature. 153 184 - T 28-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CU254_RS39845 51c0d1b519bba5d5c99e86adcd99ed90 225 SUPERFAMILY SSF52172 2 135 3.7E-33 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS39845 51c0d1b519bba5d5c99e86adcd99ed90 225 Pfam PF00196 Bacterial regulatory proteins, luxR family 158 211 3.5E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS39845 51c0d1b519bba5d5c99e86adcd99ed90 225 Pfam PF00072 Response regulator receiver domain 5 118 1.8E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS39845 51c0d1b519bba5d5c99e86adcd99ed90 225 SMART SM00421 154 211 4.5E-23 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS39845 51c0d1b519bba5d5c99e86adcd99ed90 225 Gene3D G3DSA:3.40.50.2300 2 129 9.4E-38 T 28-03-2018 CU254_RS39845 51c0d1b519bba5d5c99e86adcd99ed90 225 Gene3D G3DSA:1.10.10.10 130 221 6.5E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS39845 51c0d1b519bba5d5c99e86adcd99ed90 225 SUPERFAMILY SSF46894 141 217 3.1E-21 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS39845 51c0d1b519bba5d5c99e86adcd99ed90 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 187 2.4E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS39845 51c0d1b519bba5d5c99e86adcd99ed90 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 171 2.4E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS39845 51c0d1b519bba5d5c99e86adcd99ed90 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 187 199 2.4E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS39845 51c0d1b519bba5d5c99e86adcd99ed90 225 SMART SM00448 3 118 1.9E-33 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS12490 94c3b02bf84d3d8b4ff693c5da60be8d 232 Pfam PF00005 ABC transporter 22 171 1.5E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS12490 94c3b02bf84d3d8b4ff693c5da60be8d 232 Gene3D G3DSA:3.40.50.300 1 227 1.1E-57 T 28-03-2018 CU254_RS12490 94c3b02bf84d3d8b4ff693c5da60be8d 232 SUPERFAMILY SSF52540 3 223 1.1E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS12490 94c3b02bf84d3d8b4ff693c5da60be8d 232 SMART SM00382 31 221 1.3E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS12490 94c3b02bf84d3d8b4ff693c5da60be8d 232 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS05565 038dc5dd4f666b6cc4ae39ebf8b0d03b 225 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 154 174 3.1E-12 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CU254_RS05565 038dc5dd4f666b6cc4ae39ebf8b0d03b 225 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 3.1E-12 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CU254_RS05565 038dc5dd4f666b6cc4ae39ebf8b0d03b 225 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 136 152 3.1E-12 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CU254_RS05565 038dc5dd4f666b6cc4ae39ebf8b0d03b 225 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 181 194 3.1E-12 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CU254_RS05565 038dc5dd4f666b6cc4ae39ebf8b0d03b 225 SUPERFAMILY SSF56784 2 221 1.84E-35 T 28-03-2018 IPR023214 HAD-like domain CU254_RS05565 038dc5dd4f666b6cc4ae39ebf8b0d03b 225 Gene3D G3DSA:3.40.50.1000 1 207 4.4E-22 T 28-03-2018 IPR023214 HAD-like domain CU254_RS05565 038dc5dd4f666b6cc4ae39ebf8b0d03b 225 TIGRFAM TIGR01493 HAD-SF-IA-v2: HAD hydrolase, family IA, variant 2 5 183 2.3E-31 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CU254_RS05565 038dc5dd4f666b6cc4ae39ebf8b0d03b 225 Pfam PF00702 haloacid dehalogenase-like hydrolase 3 186 3.0E-6 T 28-03-2018 CU254_RS05565 038dc5dd4f666b6cc4ae39ebf8b0d03b 225 TIGRFAM TIGR01428 HAD_type_II: haloacid dehalogenase, type II 3 197 2.2E-48 T 28-03-2018 IPR006328 L-2-Haloacid dehalogenase GO:0008152|GO:0019120 KEGG: 00361+3.8.1.2|KEGG: 00625+3.8.1.2|MetaCyc: PWY-7425 CU254_RS10650 233e25755df9659f4aa94f7fd642413e 287 Gene3D G3DSA:1.10.3720.10 25 282 9.3E-46 T 28-03-2018 CU254_RS10650 233e25755df9659f4aa94f7fd642413e 287 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 274 5.2E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS10650 233e25755df9659f4aa94f7fd642413e 287 SUPERFAMILY SSF161098 19 281 1.12E-53 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS08865 3dad9ac4f083cb07c7b466a8fb318e1d 302 SUPERFAMILY SSF103481 40 141 3.4E-14 T 28-03-2018 CU254_RS08865 3dad9ac4f083cb07c7b466a8fb318e1d 302 SUPERFAMILY SSF103481 187 284 2.35E-14 T 28-03-2018 CU254_RS08865 3dad9ac4f083cb07c7b466a8fb318e1d 302 Pfam PF00892 EamA-like transporter family 153 280 4.9E-17 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CU254_RS08865 3dad9ac4f083cb07c7b466a8fb318e1d 302 Pfam PF00892 EamA-like transporter family 16 139 5.4E-12 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CU254_RS17115 084ddc5afd4dbbfe02015d452483178f 393 Pfam PF00067 Cytochrome P450 212 361 1.9E-24 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS17115 084ddc5afd4dbbfe02015d452483178f 393 Gene3D G3DSA:1.10.630.10 7 393 2.0E-77 T 28-03-2018 CU254_RS17115 084ddc5afd4dbbfe02015d452483178f 393 PRINTS PR00385 P450 superfamily signature 265 276 2.0E-7 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS17115 084ddc5afd4dbbfe02015d452483178f 393 PRINTS PR00385 P450 superfamily signature 230 247 2.0E-7 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS17115 084ddc5afd4dbbfe02015d452483178f 393 PRINTS PR00385 P450 superfamily signature 340 351 2.0E-7 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS17115 084ddc5afd4dbbfe02015d452483178f 393 PRINTS PR00385 P450 superfamily signature 331 340 2.0E-7 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS17115 084ddc5afd4dbbfe02015d452483178f 393 PRINTS PR00359 B-class P450 signature 189 211 1.1E-54 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS17115 084ddc5afd4dbbfe02015d452483178f 393 PRINTS PR00359 B-class P450 signature 310 325 1.1E-54 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS17115 084ddc5afd4dbbfe02015d452483178f 393 PRINTS PR00359 B-class P450 signature 340 351 1.1E-54 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS17115 084ddc5afd4dbbfe02015d452483178f 393 PRINTS PR00359 B-class P450 signature 135 151 1.1E-54 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS17115 084ddc5afd4dbbfe02015d452483178f 393 PRINTS PR00359 B-class P450 signature 152 167 1.1E-54 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS17115 084ddc5afd4dbbfe02015d452483178f 393 PRINTS PR00359 B-class P450 signature 265 276 1.1E-54 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS17115 084ddc5afd4dbbfe02015d452483178f 393 PRINTS PR00359 B-class P450 signature 331 340 1.1E-54 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS17115 084ddc5afd4dbbfe02015d452483178f 393 PRINTS PR00359 B-class P450 signature 282 309 1.1E-54 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS17115 084ddc5afd4dbbfe02015d452483178f 393 PRINTS PR00359 B-class P450 signature 88 99 1.1E-54 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS17115 084ddc5afd4dbbfe02015d452483178f 393 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 333 342 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CU254_RS17115 084ddc5afd4dbbfe02015d452483178f 393 SUPERFAMILY SSF48264 14 392 1.7E-94 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS23630 90a0867d89fc22194694e9aff9c5c17c 99 Pfam PF03334 Na+/H+ antiporter subunit 8 84 3.8E-15 T 28-03-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:0015992 CU254_RS18835 401fbec7f869d9ce227c06f1b0a3d0f5 445 Pfam PF07690 Major Facilitator Superfamily 30 378 3.3E-32 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS18835 401fbec7f869d9ce227c06f1b0a3d0f5 445 Gene3D G3DSA:1.20.1250.20 241 445 1.2E-25 T 28-03-2018 CU254_RS18835 401fbec7f869d9ce227c06f1b0a3d0f5 445 Gene3D G3DSA:1.20.1250.20 17 236 3.8E-25 T 28-03-2018 CU254_RS18835 401fbec7f869d9ce227c06f1b0a3d0f5 445 ProSitePatterns PS00216 Sugar transport proteins signature 1. 305 322 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CU254_RS18835 401fbec7f869d9ce227c06f1b0a3d0f5 445 SUPERFAMILY SSF103473 19 435 1.06E-68 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS35155 64e0f7e3967ed50c404f75354a5befba 552 Pfam PF13193 AMP-binding enzyme C-terminal domain 451 527 5.9E-16 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS35155 64e0f7e3967ed50c404f75354a5befba 552 Gene3D G3DSA:3.30.300.30 435 538 3.8E-29 T 28-03-2018 CU254_RS35155 64e0f7e3967ed50c404f75354a5befba 552 Gene3D G3DSA:3.40.50.980 196 350 3.9E-55 T 28-03-2018 CU254_RS35155 64e0f7e3967ed50c404f75354a5befba 552 Gene3D G3DSA:3.40.50.980 21 195 2.8E-44 T 28-03-2018 CU254_RS35155 64e0f7e3967ed50c404f75354a5befba 552 ProSitePatterns PS00455 Putative AMP-binding domain signature. 191 202 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS35155 64e0f7e3967ed50c404f75354a5befba 552 SUPERFAMILY SSF56801 20 537 8.24E-167 T 28-03-2018 CU254_RS35155 64e0f7e3967ed50c404f75354a5befba 552 Gene3D G3DSA:2.30.38.10 351 434 3.7E-27 T 28-03-2018 CU254_RS35155 64e0f7e3967ed50c404f75354a5befba 552 Pfam PF00501 AMP-binding enzyme 28 442 6.5E-115 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS30095 1ba3d6ca6d5565717da0fe5f4963359e 224 Pfam PF02585 GlcNAc-PI de-N-acetylase 6 126 6.1E-19 T 28-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 CU254_RS30095 1ba3d6ca6d5565717da0fe5f4963359e 224 Gene3D G3DSA:3.40.50.10320 1 224 9.1E-39 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CU254_RS30095 1ba3d6ca6d5565717da0fe5f4963359e 224 SUPERFAMILY SSF102588 3 222 4.19E-37 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CU254_RS17465 b0c707f20a7f2f5766ab608d3f6da8a8 80 SUPERFAMILY SSF54285 8 80 4.65E-11 T 28-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp CU254_RS17465 b0c707f20a7f2f5766ab608d3f6da8a8 80 Gene3D G3DSA:3.10.20.30 7 80 1.1E-8 T 28-03-2018 IPR012675 Beta-grasp domain CU254_RS17465 b0c707f20a7f2f5766ab608d3f6da8a8 80 Pfam PF02597 ThiS family 15 80 1.6E-7 T 28-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 CU254_RS05985 74f5b52969eeb69041b0932b722e2b15 601 SUPERFAMILY SSF52540 45 266 2.54E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS05985 74f5b52969eeb69041b0932b722e2b15 601 Pfam PF00350 Dynamin family 53 193 1.1E-6 T 28-03-2018 IPR022812 Dynamin superfamily CU254_RS05985 74f5b52969eeb69041b0932b722e2b15 601 Gene3D G3DSA:3.40.50.300 31 369 3.7E-27 T 28-03-2018 CU254_RS32045 7dad757a6dd27ba518f0d1111d39488f 148 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 11 119 3.2E-6 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase CU254_RS32045 7dad757a6dd27ba518f0d1111d39488f 148 SUPERFAMILY SSF55961 10 146 4.93E-9 T 28-03-2018 CU254_RS32045 7dad757a6dd27ba518f0d1111d39488f 148 Gene3D G3DSA:3.30.530.20 3 146 3.0E-12 T 28-03-2018 IPR023393 START-like domain CU254_RS12450 59f5babc8cb70207e5113ae04ccd811d 179 SUPERFAMILY SSF46689 6 66 4.04E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS12450 59f5babc8cb70207e5113ae04ccd811d 179 Gene3D G3DSA:1.10.357.10 63 179 3.0E-13 T 28-03-2018 CU254_RS12450 59f5babc8cb70207e5113ae04ccd811d 179 Pfam PF16859 Bacterial transcriptional repressor C-terminal 72 177 2.2E-18 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS12450 59f5babc8cb70207e5113ae04ccd811d 179 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 59 1.9E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS12450 59f5babc8cb70207e5113ae04ccd811d 179 SUPERFAMILY SSF48498 74 178 1.32E-15 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS12450 59f5babc8cb70207e5113ae04ccd811d 179 Gene3D G3DSA:1.10.10.60 1 62 1.7E-14 T 28-03-2018 CU254_RS28555 31f3ef551ff2e8e28fd8c0ff71f6f647 207 Gene3D G3DSA:3.40.50.10230 2 206 7.8E-77 T 28-03-2018 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 CU254_RS28555 31f3ef551ff2e8e28fd8c0ff71f6f647 207 SUPERFAMILY SSF63965 2 204 1.83E-72 T 28-03-2018 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 CU254_RS28555 31f3ef551ff2e8e28fd8c0ff71f6f647 207 Pfam PF02570 Precorrin-8X methylmutase 10 204 5.9E-71 T 28-03-2018 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 CU254_RS30105 30b65238bc1488c8f6fe46b6fdd30675 319 Gene3D G3DSA:3.40.50.720 2 319 1.8E-70 T 28-03-2018 CU254_RS30105 30b65238bc1488c8f6fe46b6fdd30675 319 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 311 1.7E-55 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS30105 30b65238bc1488c8f6fe46b6fdd30675 319 SUPERFAMILY SSF51735 2 316 3.36E-84 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS39000 2eb0976e354822fb0718133e7ca2ea89 259 SUPERFAMILY SSF53213 4 250 3.01E-83 T 28-03-2018 CU254_RS39000 2eb0976e354822fb0718133e7ca2ea89 259 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 23 238 2.8E-44 T 28-03-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 CU254_RS39000 2eb0976e354822fb0718133e7ca2ea89 259 PIRSF PIRSF006157 1 259 8.8E-86 T 28-03-2018 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA-type GO:0008270|GO:0016701|GO:0055114 CU254_RS39000 2eb0976e354822fb0718133e7ca2ea89 259 Gene3D G3DSA:3.40.830.10 1 258 3.6E-80 T 28-03-2018 CU254_RS17770 e71b38c46ca9bc2e988ac9f525cc59f6 444 Pfam PF01943 Polysaccharide biosynthesis protein 18 275 4.9E-13 T 28-03-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 CU254_RS12755 77f2f2ee854c2ef4d25dec3b443fb840 397 Gene3D G3DSA:1.10.10.60 344 397 0.0091 T 28-03-2018 CU254_RS12755 77f2f2ee854c2ef4d25dec3b443fb840 397 Pfam PF14525 AraC-binding-like domain 94 273 1.1E-38 T 28-03-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like CU254_RS12755 77f2f2ee854c2ef4d25dec3b443fb840 397 Gene3D G3DSA:1.10.10.60 291 343 1.8E-4 T 28-03-2018 CU254_RS12755 77f2f2ee854c2ef4d25dec3b443fb840 397 Pfam PF12833 Helix-turn-helix domain 316 397 4.0E-12 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS12755 77f2f2ee854c2ef4d25dec3b443fb840 397 SMART SM00342 310 395 9.8E-5 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS25060 10110523e9ecb86e32f4be49018a384b 389 TIGRFAM TIGR01266 fum_ac_acetase: fumarylacetoacetase 4 388 1.4E-129 T 28-03-2018 IPR005959 Fumarylacetoacetase GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 CU254_RS25060 10110523e9ecb86e32f4be49018a384b 389 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 104 385 1.2E-53 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CU254_RS25060 10110523e9ecb86e32f4be49018a384b 389 Pfam PF09298 Fumarylacetoacetase N-terminal 15 98 1.7E-18 T 28-03-2018 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 CU254_RS25060 10110523e9ecb86e32f4be49018a384b 389 Gene3D G3DSA:2.30.30.230 2 98 2.0E-25 T 28-03-2018 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 CU254_RS25060 10110523e9ecb86e32f4be49018a384b 389 SUPERFAMILY SSF63433 2 98 2.48E-25 T 28-03-2018 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 CU254_RS25060 10110523e9ecb86e32f4be49018a384b 389 Gene3D G3DSA:3.90.850.10 99 373 2.9E-79 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CU254_RS25060 10110523e9ecb86e32f4be49018a384b 389 SUPERFAMILY SSF56529 100 388 3.66E-86 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CU254_RS30770 a4959b26880355a8ce26aa1d898ef561 607 Pfam PF00501 AMP-binding enzyme 19 477 3.5E-81 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS30770 a4959b26880355a8ce26aa1d898ef561 607 Gene3D G3DSA:3.40.50.980 9 197 9.9E-39 T 28-03-2018 CU254_RS30770 a4959b26880355a8ce26aa1d898ef561 607 Gene3D G3DSA:2.30.38.10 398 470 1.5E-17 T 28-03-2018 CU254_RS30770 a4959b26880355a8ce26aa1d898ef561 607 Gene3D G3DSA:3.40.50.980 198 397 3.2E-35 T 28-03-2018 CU254_RS30770 a4959b26880355a8ce26aa1d898ef561 607 SUPERFAMILY SSF56801 347 606 1.44E-110 T 28-03-2018 CU254_RS30770 a4959b26880355a8ce26aa1d898ef561 607 SUPERFAMILY SSF56801 12 295 1.44E-110 T 28-03-2018 CU254_RS30770 a4959b26880355a8ce26aa1d898ef561 607 ProSitePatterns PS00455 Putative AMP-binding domain signature. 192 203 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS30770 a4959b26880355a8ce26aa1d898ef561 607 Gene3D G3DSA:3.30.300.30 472 607 4.1E-18 T 28-03-2018 CU254_RS03790 3ee95e7375f4ff2d65a8e83cbbd2a816 381 Gene3D G3DSA:3.40.50.300 94 371 8.7E-57 T 28-03-2018 CU254_RS03790 3ee95e7375f4ff2d65a8e83cbbd2a816 381 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 117 362 1.5E-88 T 28-03-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 CU254_RS03790 3ee95e7375f4ff2d65a8e83cbbd2a816 381 SUPERFAMILY SSF117916 9 99 6.54E-24 T 28-03-2018 IPR034904 Fe-S cluster assembly domain CU254_RS03790 3ee95e7375f4ff2d65a8e83cbbd2a816 381 SUPERFAMILY SSF52540 116 362 8.31E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS03790 3ee95e7375f4ff2d65a8e83cbbd2a816 381 Hamap MF_02040 Iron-sulfur cluster carrier protein. 97 363 33.601 T 28-03-2018 IPR019591 Mrp/NBP35 ATP-binding protein CU254_RS03790 3ee95e7375f4ff2d65a8e83cbbd2a816 381 Gene3D G3DSA:3.30.300.130 7 93 1.4E-20 T 28-03-2018 IPR034904 Fe-S cluster assembly domain CU254_RS03790 3ee95e7375f4ff2d65a8e83cbbd2a816 381 Pfam PF01883 Iron-sulfur cluster assembly protein 11 83 1.0E-18 T 28-03-2018 IPR002744 MIP18 family-like CU254_RS09220 fc1fcc887ab58e72a1c066a10c945be5 182 Hamap MF_00299 Probable RNA 2'-phosphotransferase [kptA]. 5 178 31.305 T 28-03-2018 IPR022928 RNA 2'-phosphotransferase KptA, putative GO:0016773 CU254_RS09220 fc1fcc887ab58e72a1c066a10c945be5 182 Pfam PF01885 RNA 2'-phosphotransferase, Tpt1 / KptA family 5 171 1.7E-38 T 28-03-2018 IPR002745 Phosphotransferase KptA/Tpt1 GO:0006388|GO:0016772 CU254_RS09220 fc1fcc887ab58e72a1c066a10c945be5 182 SUPERFAMILY SSF56399 8 180 1.5E-55 T 28-03-2018 CU254_RS28565 b47ea01f875b0dcde9fa5fbf74aec95f 301 Pfam PF00005 ABC transporter 24 171 1.5E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS28565 b47ea01f875b0dcde9fa5fbf74aec95f 301 SUPERFAMILY SSF52540 5 232 3.48E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS28565 b47ea01f875b0dcde9fa5fbf74aec95f 301 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS28565 b47ea01f875b0dcde9fa5fbf74aec95f 301 Gene3D G3DSA:3.40.50.300 5 291 6.3E-59 T 28-03-2018 CU254_RS28565 b47ea01f875b0dcde9fa5fbf74aec95f 301 SMART SM00382 33 227 7.0E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS08010 63a54de8cf6af5321a16a77d6bd2485d 126 Hamap MF_00048 UPF0102 protein YraN [yraN]. 12 122 21.632 T 28-03-2018 IPR003509 Uncharacterised protein family UPF0102 CU254_RS08010 63a54de8cf6af5321a16a77d6bd2485d 126 Pfam PF02021 Uncharacterised protein family UPF0102 19 109 2.2E-27 T 28-03-2018 IPR003509 Uncharacterised protein family UPF0102 CU254_RS08010 63a54de8cf6af5321a16a77d6bd2485d 126 TIGRFAM TIGR00252 TIGR00252: TIGR00252 family protein 13 115 3.3E-20 T 28-03-2018 IPR003509 Uncharacterised protein family UPF0102 CU254_RS08010 63a54de8cf6af5321a16a77d6bd2485d 126 Gene3D G3DSA:3.40.1350.10 18 126 6.5E-34 T 28-03-2018 CU254_RS08010 63a54de8cf6af5321a16a77d6bd2485d 126 SUPERFAMILY SSF52980 17 111 1.5E-18 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CU254_RS32705 41fe2cdd37c07093b94e99d490a246f9 334 Pfam PF00005 ABC transporter 20 160 3.9E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS32705 41fe2cdd37c07093b94e99d490a246f9 334 Pfam PF08402 TOBE domain 266 332 2.7E-5 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CU254_RS32705 41fe2cdd37c07093b94e99d490a246f9 334 SUPERFAMILY SSF52540 3 239 1.14E-76 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS32705 41fe2cdd37c07093b94e99d490a246f9 334 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS32705 41fe2cdd37c07093b94e99d490a246f9 334 Gene3D G3DSA:3.40.50.300 1 244 2.2E-70 T 28-03-2018 CU254_RS32705 41fe2cdd37c07093b94e99d490a246f9 334 SMART SM00382 27 210 1.6E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS32705 41fe2cdd37c07093b94e99d490a246f9 334 SUPERFAMILY SSF50331 238 331 8.5E-11 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CU254_RS37100 87a71406a0155995ca853a74c71fc5d5 1017 Gene3D G3DSA:2.60.40.1180 904 1016 3.6E-5 T 28-03-2018 CU254_RS37100 87a71406a0155995ca853a74c71fc5d5 1017 Gene3D G3DSA:2.60.40.1180 813 903 5.8E-27 T 28-03-2018 CU254_RS37100 87a71406a0155995ca853a74c71fc5d5 1017 SUPERFAMILY SSF49785 266 400 1.21E-14 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS37100 87a71406a0155995ca853a74c71fc5d5 1017 Pfam PF03422 Carbohydrate binding module (family 6) 317 399 6.8E-6 T 28-03-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 CU254_RS37100 87a71406a0155995ca853a74c71fc5d5 1017 Pfam PF16990 Carbohydrate binding module (family 35) 124 249 4.5E-11 T 28-03-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 CU254_RS37100 87a71406a0155995ca853a74c71fc5d5 1017 Gene3D G3DSA:2.60.120.260 269 404 8.6E-24 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS37100 87a71406a0155995ca853a74c71fc5d5 1017 Gene3D G3DSA:2.60.120.260 119 252 5.8E-28 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS37100 87a71406a0155995ca853a74c71fc5d5 1017 SUPERFAMILY SSF51445 481 819 1.09E-41 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS37100 87a71406a0155995ca853a74c71fc5d5 1017 SUPERFAMILY SSF51011 820 902 6.55E-16 T 28-03-2018 CU254_RS37100 87a71406a0155995ca853a74c71fc5d5 1017 Gene3D G3DSA:3.20.20.80 491 812 1.6E-60 T 28-03-2018 CU254_RS37100 87a71406a0155995ca853a74c71fc5d5 1017 SUPERFAMILY SSF49785 122 250 2.79E-21 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS37100 87a71406a0155995ca853a74c71fc5d5 1017 Pfam PF01055 Glycosyl hydrolases family 31 472 907 3.1E-80 T 28-03-2018 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 CU254_RS21340 a31c085c728dc709e0aa49cab27df32c 486 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 84 98 - T 28-03-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CU254_RS21340 a31c085c728dc709e0aa49cab27df32c 486 SUPERFAMILY SSF52283 196 243 1.59E-108 T 28-03-2018 CU254_RS21340 a31c085c728dc709e0aa49cab27df32c 486 SUPERFAMILY SSF52283 407 486 1.59E-108 T 28-03-2018 CU254_RS21340 a31c085c728dc709e0aa49cab27df32c 486 SUPERFAMILY SSF52283 11 158 1.59E-108 T 28-03-2018 CU254_RS21340 a31c085c728dc709e0aa49cab27df32c 486 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 13 478 2.6E-179 T 28-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CU254_RS21340 a31c085c728dc709e0aa49cab27df32c 486 PIRSF PIRSF001109 3 486 1.9E-181 T 28-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CU254_RS21340 a31c085c728dc709e0aa49cab27df32c 486 SUPERFAMILY SSF51735 244 406 4.74E-72 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS21340 a31c085c728dc709e0aa49cab27df32c 486 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 244 406 1.2E-75 T 28-03-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CU254_RS21340 a31c085c728dc709e0aa49cab27df32c 486 SMART SM00997 244 406 4.2E-98 T 28-03-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CU254_RS21340 a31c085c728dc709e0aa49cab27df32c 486 Gene3D G3DSA:3.40.50.1480 257 459 4.1E-78 T 28-03-2018 CU254_RS21340 a31c085c728dc709e0aa49cab27df32c 486 SMART SM00996 12 485 0.0 T 28-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CU254_RS21340 a31c085c728dc709e0aa49cab27df32c 486 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 12 485 4.7E-139 T 28-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CU254_RS21340 a31c085c728dc709e0aa49cab27df32c 486 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 8 478 47.366 T 28-03-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508 CU254_RS21340 a31c085c728dc709e0aa49cab27df32c 486 Gene3D G3DSA:3.40.50.1480 4 254 1.0E-103 T 28-03-2018 CU254_RS07255 5f6f9f0890f927f4cc970085856e235a 351 Gene3D G3DSA:1.20.1170.10 114 338 3.8E-7 T 28-03-2018 CU254_RS07255 5f6f9f0890f927f4cc970085856e235a 351 Pfam PF02470 MlaD protein 42 117 2.2E-16 T 28-03-2018 IPR003399 Mce/MlaD CU254_RS07255 5f6f9f0890f927f4cc970085856e235a 351 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 170 283 7.1E-9 T 28-03-2018 IPR024516 Mammalian cell entry, C-terminal CU254_RS07255 5f6f9f0890f927f4cc970085856e235a 351 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 24 302 5.0E-65 T 28-03-2018 IPR005693 Virulence factor Mce protein CU254_RS26610 99da14db81d2bc49cfba41566eaa972d 420 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 5 415 7.1E-164 T 28-03-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 CU254_RS26610 99da14db81d2bc49cfba41566eaa972d 420 Gene3D G3DSA:2.40.30.10 311 416 5.7E-24 T 28-03-2018 CU254_RS26610 99da14db81d2bc49cfba41566eaa972d 420 Gene3D G3DSA:2.40.30.10 203 309 3.5E-21 T 28-03-2018 CU254_RS26610 99da14db81d2bc49cfba41566eaa972d 420 Pfam PF00009 Elongation factor Tu GTP binding domain 5 190 1.1E-38 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CU254_RS26610 99da14db81d2bc49cfba41566eaa972d 420 SUPERFAMILY SSF52540 3 212 1.29E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS26610 99da14db81d2bc49cfba41566eaa972d 420 Gene3D G3DSA:3.40.50.300 2 202 5.9E-36 T 28-03-2018 CU254_RS26610 99da14db81d2bc49cfba41566eaa972d 420 SUPERFAMILY SSF50465 312 415 8.63E-25 T 28-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal CU254_RS26610 99da14db81d2bc49cfba41566eaa972d 420 PRINTS PR00315 GTP-binding elongation factor signature 6 19 8.1E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CU254_RS26610 99da14db81d2bc49cfba41566eaa972d 420 PRINTS PR00315 GTP-binding elongation factor signature 65 73 8.1E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CU254_RS26610 99da14db81d2bc49cfba41566eaa972d 420 PRINTS PR00315 GTP-binding elongation factor signature 85 95 8.1E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CU254_RS26610 99da14db81d2bc49cfba41566eaa972d 420 PRINTS PR00315 GTP-binding elongation factor signature 101 112 8.1E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CU254_RS26610 99da14db81d2bc49cfba41566eaa972d 420 PRINTS PR00315 GTP-binding elongation factor signature 138 147 8.1E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CU254_RS26610 99da14db81d2bc49cfba41566eaa972d 420 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 58 73 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site CU254_RS26610 99da14db81d2bc49cfba41566eaa972d 420 SUPERFAMILY SSF50447 217 310 8.73E-20 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CU254_RS37690 44f9c7573e405a22b8d89e11bee63975 526 Pfam PF00732 GMC oxidoreductase 7 297 6.9E-95 T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CU254_RS37690 44f9c7573e405a22b8d89e11bee63975 526 Gene3D G3DSA:4.10.450.10 39 103 2.2E-28 T 28-03-2018 CU254_RS37690 44f9c7573e405a22b8d89e11bee63975 526 PIRSF PIRSF000137 1 526 1.6E-153 T 28-03-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CU254_RS37690 44f9c7573e405a22b8d89e11bee63975 526 SUPERFAMILY SSF54373 291 469 1.18E-40 T 28-03-2018 CU254_RS37690 44f9c7573e405a22b8d89e11bee63975 526 Pfam PF05199 GMC oxidoreductase 385 519 4.4E-36 T 28-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 CU254_RS37690 44f9c7573e405a22b8d89e11bee63975 526 SUPERFAMILY SSF51905 5 289 2.59E-95 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS37690 44f9c7573e405a22b8d89e11bee63975 526 SUPERFAMILY SSF51905 468 525 2.59E-95 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS37690 44f9c7573e405a22b8d89e11bee63975 526 Gene3D G3DSA:3.30.560.10 104 481 2.8E-103 T 28-03-2018 CU254_RS37690 44f9c7573e405a22b8d89e11bee63975 526 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 255 269 - T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CU254_RS12855 0ead5d4307a47eafdbf75719351b8d77 315 Gene3D G3DSA:3.40.50.970 1 314 3.8E-76 T 28-03-2018 CU254_RS12855 0ead5d4307a47eafdbf75719351b8d77 315 Pfam PF00676 Dehydrogenase E1 component 8 297 7.3E-74 T 28-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 CU254_RS12855 0ead5d4307a47eafdbf75719351b8d77 315 SUPERFAMILY SSF52518 2 309 8.01E-89 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS34245 77c46d11c255c9826080ef0eb4fe557d 230 SMART SM00862 150 225 2.6E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS34245 77c46d11c255c9826080ef0eb4fe557d 230 Gene3D G3DSA:3.40.50.2300 1 125 3.2E-42 T 28-03-2018 CU254_RS34245 77c46d11c255c9826080ef0eb4fe557d 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 225 5.9E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS34245 77c46d11c255c9826080ef0eb4fe557d 230 SUPERFAMILY SSF52172 1 184 1.01E-44 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS34245 77c46d11c255c9826080ef0eb4fe557d 230 SMART SM00448 1 112 4.3E-46 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS34245 77c46d11c255c9826080ef0eb4fe557d 230 Gene3D G3DSA:1.10.10.10 126 229 2.5E-34 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS34245 77c46d11c255c9826080ef0eb4fe557d 230 Pfam PF00072 Response regulator receiver domain 3 112 9.0E-32 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS24925 a30181a86ec2d3fb94617388f14e68b6 189 SUPERFAMILY SSF48498 85 187 4.08E-8 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS24925 a30181a86ec2d3fb94617388f14e68b6 189 SUPERFAMILY SSF46689 8 80 1.21E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS24925 a30181a86ec2d3fb94617388f14e68b6 189 Gene3D G3DSA:1.10.357.10 2 189 2.3E-33 T 28-03-2018 CU254_RS24925 a30181a86ec2d3fb94617388f14e68b6 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 64 1.6E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS24925 a30181a86ec2d3fb94617388f14e68b6 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 7.0E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS24925 a30181a86ec2d3fb94617388f14e68b6 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 7.0E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS04725 7bd60dfee8c2a1a6fb59772c39f796de 357 Pfam PF01758 Sodium Bile acid symporter family 57 253 3.8E-63 T 28-03-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 CU254_RS04725 7bd60dfee8c2a1a6fb59772c39f796de 357 PIRSF PIRSF005508 3 355 2.2E-135 T 28-03-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 CU254_RS04725 7bd60dfee8c2a1a6fb59772c39f796de 357 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 12 340 1.6E-133 T 28-03-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 CU254_RS13455 5c7fd12691a2348bb347ab191f246e98 319 SUPERFAMILY SSF52540 21 256 1.17E-66 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS13455 5c7fd12691a2348bb347ab191f246e98 319 SMART SM00382 38 227 1.3E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS13455 5c7fd12691a2348bb347ab191f246e98 319 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 229 292 6.8E-15 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CU254_RS13455 5c7fd12691a2348bb347ab191f246e98 319 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS13455 5c7fd12691a2348bb347ab191f246e98 319 Gene3D G3DSA:3.40.50.300 1 314 2.1E-73 T 28-03-2018 CU254_RS13455 5c7fd12691a2348bb347ab191f246e98 319 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 227 310 1.3E-19 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CU254_RS13455 5c7fd12691a2348bb347ab191f246e98 319 Pfam PF00005 ABC transporter 29 178 1.7E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS35120 a939f54e4f709c3307b6eae2d2a6bdd2 655 SUPERFAMILY SSF103473 235 621 2.62E-19 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS35120 a939f54e4f709c3307b6eae2d2a6bdd2 655 Pfam PF07690 Major Facilitator Superfamily 240 589 7.2E-16 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS35120 a939f54e4f709c3307b6eae2d2a6bdd2 655 Gene3D G3DSA:1.20.1250.20 430 623 1.0E-8 T 28-03-2018 CU254_RS35120 a939f54e4f709c3307b6eae2d2a6bdd2 655 Gene3D G3DSA:1.20.1250.20 229 429 4.1E-13 T 28-03-2018 CU254_RS15125 214e712f40f574c18849ff361b028ed2 499 Gene3D G3DSA:2.30.38.10 307 390 2.7E-28 T 28-03-2018 CU254_RS15125 214e712f40f574c18849ff361b028ed2 499 Gene3D G3DSA:3.30.300.30 392 499 4.8E-32 T 28-03-2018 CU254_RS15125 214e712f40f574c18849ff361b028ed2 499 Pfam PF13193 AMP-binding enzyme C-terminal domain 406 480 5.9E-24 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS15125 214e712f40f574c18849ff361b028ed2 499 SUPERFAMILY SSF56801 4 492 4.71E-160 T 28-03-2018 CU254_RS15125 214e712f40f574c18849ff361b028ed2 499 ProSitePatterns PS00455 Putative AMP-binding domain signature. 151 162 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS15125 214e712f40f574c18849ff361b028ed2 499 Gene3D G3DSA:3.40.50.980 156 306 6.0E-49 T 28-03-2018 CU254_RS15125 214e712f40f574c18849ff361b028ed2 499 Pfam PF00501 AMP-binding enzyme 11 397 2.8E-106 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS15125 214e712f40f574c18849ff361b028ed2 499 Gene3D G3DSA:3.40.50.980 2 155 1.9E-43 T 28-03-2018 CU254_RS24155 da068ea68815e0664325e7a7ccaa91dc 236 Pfam PF00005 ABC transporter 42 187 8.3E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS24155 da068ea68815e0664325e7a7ccaa91dc 236 Gene3D G3DSA:3.40.50.300 19 236 1.9E-60 T 28-03-2018 CU254_RS24155 da068ea68815e0664325e7a7ccaa91dc 236 SMART SM00382 51 234 6.6E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS24155 da068ea68815e0664325e7a7ccaa91dc 236 SUPERFAMILY SSF52540 39 235 1.85E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS10765 ab16f6dc3035c696a16459b075108fec 266 SUPERFAMILY SSF103481 23 112 2.09E-8 T 28-03-2018 CU254_RS10765 ab16f6dc3035c696a16459b075108fec 266 Pfam PF00892 EamA-like transporter family 122 252 1.1E-14 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CU254_RS10765 ab16f6dc3035c696a16459b075108fec 266 SUPERFAMILY SSF103481 158 256 5.23E-9 T 28-03-2018 CU254_RS09505 aba65d9b0a659485cd0de68ac3a950eb 254 Pfam PF07398 MDMPI C-terminal domain 147 241 2.9E-11 T 28-03-2018 IPR010872 MDMPI C-terminal CU254_RS09505 aba65d9b0a659485cd0de68ac3a950eb 254 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 20 227 3.4E-14 T 28-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CU254_RS09505 aba65d9b0a659485cd0de68ac3a950eb 254 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 21 133 6.5E-11 T 28-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CU254_RS09505 aba65d9b0a659485cd0de68ac3a950eb 254 Gene3D G3DSA:1.20.120.450 3 140 1.6E-9 T 28-03-2018 CU254_RS14015 465a85c2745d5930dbd4eab005c0d8c1 276 SMART SM00382 35 224 4.3E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS14015 465a85c2745d5930dbd4eab005c0d8c1 276 SUPERFAMILY SSF52540 11 237 1.33E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS14015 465a85c2745d5930dbd4eab005c0d8c1 276 Gene3D G3DSA:3.40.50.300 1 245 6.4E-51 T 28-03-2018 CU254_RS14015 465a85c2745d5930dbd4eab005c0d8c1 276 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS14015 465a85c2745d5930dbd4eab005c0d8c1 276 Pfam PF00005 ABC transporter 28 174 3.1E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS32390 6dc3cedbc9a718dcbf8ae958ce2fa105 339 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 36 333 25.211 T 28-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 CU254_RS32390 6dc3cedbc9a718dcbf8ae958ce2fa105 339 Gene3D G3DSA:3.40.50.300 114 266 3.9E-20 T 28-03-2018 CU254_RS32390 6dc3cedbc9a718dcbf8ae958ce2fa105 339 Gene3D G3DSA:1.10.40.50 267 331 1.7E-17 T 28-03-2018 CU254_RS32390 6dc3cedbc9a718dcbf8ae958ce2fa105 339 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 73 321 9.0E-42 T 28-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 CU254_RS32390 6dc3cedbc9a718dcbf8ae958ce2fa105 339 Pfam PF03193 RsgA GTPase 99 266 1.8E-41 T 28-03-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 CU254_RS32390 6dc3cedbc9a718dcbf8ae958ce2fa105 339 SUPERFAMILY SSF52540 116 321 1.49E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS00865 e62b4273ca07d70f8ef388536ebf9f6d 155 Gene3D G3DSA:1.10.3300.10 2 152 4.3E-30 T 28-03-2018 IPR023286 ABATE domain CU254_RS00865 e62b4273ca07d70f8ef388536ebf9f6d 155 Pfam PF07336 Putative stress-induced transcription regulator 7 97 7.3E-6 T 28-03-2018 IPR010852 Putative stress-induced transcription regulator CU254_RS00865 e62b4273ca07d70f8ef388536ebf9f6d 155 Pfam PF11706 CGNR zinc finger 107 149 9.6E-19 T 28-03-2018 IPR021005 Zinc finger, CGNR CU254_RS00865 e62b4273ca07d70f8ef388536ebf9f6d 155 SUPERFAMILY SSF160904 3 149 2.48E-33 T 28-03-2018 CU254_RS06480 39206c64b32b1644bfdd1caa30586446 847 SUPERFAMILY SSF53756 4 733 6.67E-194 T 28-03-2018 CU254_RS06480 39206c64b32b1644bfdd1caa30586446 847 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 598 610 - T 28-03-2018 IPR035090 Phosphorylase pyridoxal-phosphate attachment site KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CU254_RS06480 39206c64b32b1644bfdd1caa30586446 847 Gene3D G3DSA:3.40.50.2000 95 251 4.0E-33 T 28-03-2018 CU254_RS06480 39206c64b32b1644bfdd1caa30586446 847 Gene3D G3DSA:3.40.50.2000 252 430 1.4E-50 T 28-03-2018 CU254_RS06480 39206c64b32b1644bfdd1caa30586446 847 Pfam PF11897 Protein of unknown function (DUF3417) 13 120 6.5E-35 T 28-03-2018 IPR024517 Glycogen phosphorylase, domain of unknown function DUF3417 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 CU254_RS06480 39206c64b32b1644bfdd1caa30586446 847 TIGRFAM TIGR02094 more_P_ylases: alpha-glucan phosphorylases 107 708 5.3E-228 T 28-03-2018 IPR011834 Alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 CU254_RS06480 39206c64b32b1644bfdd1caa30586446 847 Gene3D G3DSA:3.40.50.2000 440 728 1.2E-78 T 28-03-2018 CU254_RS06480 39206c64b32b1644bfdd1caa30586446 847 Pfam PF00343 Carbohydrate phosphorylase 125 170 1.2E-5 T 28-03-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CU254_RS06480 39206c64b32b1644bfdd1caa30586446 847 Pfam PF00343 Carbohydrate phosphorylase 268 620 1.5E-19 T 28-03-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CU254_RS06480 39206c64b32b1644bfdd1caa30586446 847 PIRSF PIRSF000460 1 796 3.6E-249 T 28-03-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CU254_RS33135 9ed984108aceb5f8fe0562736def89ec 303 SUPERFAMILY SSF53474 33 275 7.32E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS33135 9ed984108aceb5f8fe0562736def89ec 303 Gene3D G3DSA:3.40.50.1820 44 299 3.8E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS33135 9ed984108aceb5f8fe0562736def89ec 303 Pfam PF10503 Esterase PHB depolymerase 100 184 5.9E-5 T 28-03-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 CU254_RS09870 0fa36d90977c8a1b77f2743a21b575bf 394 SUPERFAMILY SSF54211 5 212 5.09E-51 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CU254_RS09870 0fa36d90977c8a1b77f2743a21b575bf 394 PRINTS PR00959 Mevalonate kinase family signature 171 190 8.0E-39 T 28-03-2018 CU254_RS09870 0fa36d90977c8a1b77f2743a21b575bf 394 PRINTS PR00959 Mevalonate kinase family signature 120 142 8.0E-39 T 28-03-2018 CU254_RS09870 0fa36d90977c8a1b77f2743a21b575bf 394 PRINTS PR00959 Mevalonate kinase family signature 338 355 8.0E-39 T 28-03-2018 CU254_RS09870 0fa36d90977c8a1b77f2743a21b575bf 394 PRINTS PR00959 Mevalonate kinase family signature 25 49 8.0E-39 T 28-03-2018 CU254_RS09870 0fa36d90977c8a1b77f2743a21b575bf 394 ProSitePatterns PS00106 Galactokinase signature. 27 38 - T 28-03-2018 IPR019741 Galactokinase, conserved site KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CU254_RS09870 0fa36d90977c8a1b77f2743a21b575bf 394 Pfam PF10509 Galactokinase galactose-binding signature 10 58 8.6E-21 T 28-03-2018 IPR019539 Galactokinase galactose-binding domain GO:0005534 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CU254_RS09870 0fa36d90977c8a1b77f2743a21b575bf 394 Pfam PF00288 GHMP kinases N terminal domain 115 189 6.4E-11 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CU254_RS09870 0fa36d90977c8a1b77f2743a21b575bf 394 Pfam PF08544 GHMP kinases C terminal 292 370 9.0E-13 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CU254_RS09870 0fa36d90977c8a1b77f2743a21b575bf 394 PRINTS PR00473 Galactokinase signature 275 289 4.5E-25 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CU254_RS09870 0fa36d90977c8a1b77f2743a21b575bf 394 PRINTS PR00473 Galactokinase signature 94 105 4.5E-25 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CU254_RS09870 0fa36d90977c8a1b77f2743a21b575bf 394 PRINTS PR00473 Galactokinase signature 113 131 4.5E-25 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CU254_RS09870 0fa36d90977c8a1b77f2743a21b575bf 394 PRINTS PR00473 Galactokinase signature 27 45 4.5E-25 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CU254_RS09870 0fa36d90977c8a1b77f2743a21b575bf 394 SUPERFAMILY SSF55060 216 390 4.96E-48 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CU254_RS09870 0fa36d90977c8a1b77f2743a21b575bf 394 Gene3D G3DSA:3.30.230.10 3 217 4.7E-53 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CU254_RS09870 0fa36d90977c8a1b77f2743a21b575bf 394 TIGRFAM TIGR00131 gal_kin: galactokinase 7 373 3.8E-79 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CU254_RS09870 0fa36d90977c8a1b77f2743a21b575bf 394 PIRSF PIRSF000530 2 392 1.7E-108 T 28-03-2018 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CU254_RS09870 0fa36d90977c8a1b77f2743a21b575bf 394 Gene3D G3DSA:3.30.70.890 218 391 2.3E-50 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CU254_RS21755 21ed09599a0b74f78ebb73d3b51f0c1a 185 ProDom PD103079 MB0101 RV0098/MT0107 ML1993 16 183 3.0E-37 T 28-03-2018 IPR022598 Long-chain fatty acyl-CoA thioesterase, Rv0098-like CU254_RS21755 21ed09599a0b74f78ebb73d3b51f0c1a 185 Pfam PF10862 FcoT-like thioesterase domain 23 181 8.6E-60 T 28-03-2018 IPR022598 Long-chain fatty acyl-CoA thioesterase, Rv0098-like CU254_RS40205 a84d261ad76e7a87f140409bc4e161de 1025 SMART SM00862 16 87 2.6E-11 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS40205 a84d261ad76e7a87f140409bc4e161de 1025 SUPERFAMILY SSF48452 775 914 2.13E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS40205 a84d261ad76e7a87f140409bc4e161de 1025 Gene3D G3DSA:1.25.40.10 583 813 6.1E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS40205 a84d261ad76e7a87f140409bc4e161de 1025 Gene3D G3DSA:1.25.40.10 814 1011 2.2E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS40205 a84d261ad76e7a87f140409bc4e161de 1025 Pfam PF03704 Bacterial transcriptional activator domain 94 232 4.7E-39 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CU254_RS40205 a84d261ad76e7a87f140409bc4e161de 1025 Gene3D G3DSA:1.25.40.10 96 251 1.8E-27 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS40205 a84d261ad76e7a87f140409bc4e161de 1025 SUPERFAMILY SSF48452 89 251 1.46E-33 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS40205 a84d261ad76e7a87f140409bc4e161de 1025 Pfam PF00486 Transcriptional regulatory protein, C terminal 24 76 6.6E-9 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS40205 a84d261ad76e7a87f140409bc4e161de 1025 SMART SM01043 94 236 9.7E-48 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CU254_RS40205 a84d261ad76e7a87f140409bc4e161de 1025 Gene3D G3DSA:1.10.10.10 7 95 2.0E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS40205 a84d261ad76e7a87f140409bc4e161de 1025 PRINTS PR00364 Disease resistance protein signature 338 352 5.6E-6 T 28-03-2018 CU254_RS40205 a84d261ad76e7a87f140409bc4e161de 1025 PRINTS PR00364 Disease resistance protein signature 442 456 5.6E-6 T 28-03-2018 CU254_RS40205 a84d261ad76e7a87f140409bc4e161de 1025 PRINTS PR00364 Disease resistance protein signature 273 288 5.6E-6 T 28-03-2018 CU254_RS40205 a84d261ad76e7a87f140409bc4e161de 1025 SUPERFAMILY SSF46894 5 87 5.39E-12 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS40205 a84d261ad76e7a87f140409bc4e161de 1025 Gene3D G3DSA:3.40.50.300 252 382 4.3E-14 T 28-03-2018 CU254_RS40205 a84d261ad76e7a87f140409bc4e161de 1025 SUPERFAMILY SSF52540 247 507 3.46E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS13410 c2b62024baa85686da39e07b15c84a74 385 Gene3D G3DSA:3.40.50.2000 183 365 2.6E-43 T 28-03-2018 CU254_RS13410 c2b62024baa85686da39e07b15c84a74 385 Pfam PF13439 Glycosyltransferase Family 4 15 175 3.6E-28 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CU254_RS13410 c2b62024baa85686da39e07b15c84a74 385 TIGRFAM TIGR02149 glgA_Coryne: glycogen synthase, Corynebacterium family 1 379 2.6E-175 T 28-03-2018 IPR011875 Alpha-maltose-1-phosphate synthase GO:0009250|GO:0016740 CU254_RS13410 c2b62024baa85686da39e07b15c84a74 385 Gene3D G3DSA:3.40.50.2000 2 182 1.2E-18 T 28-03-2018 CU254_RS13410 c2b62024baa85686da39e07b15c84a74 385 Pfam PF00534 Glycosyl transferases group 1 187 331 1.5E-30 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CU254_RS13410 c2b62024baa85686da39e07b15c84a74 385 SUPERFAMILY SSF53756 1 380 1.84E-80 T 28-03-2018 CU254_RS13380 209b464d825b4a9929ebc0aeda7f2974 151 Gene3D G3DSA:1.10.10.10 23 107 1.1E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS13380 209b464d825b4a9929ebc0aeda7f2974 151 Pfam PF12802 MarR family 36 93 6.1E-10 T 28-03-2018 CU254_RS13380 209b464d825b4a9929ebc0aeda7f2974 151 SUPERFAMILY SSF46785 6 144 3.61E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS13380 209b464d825b4a9929ebc0aeda7f2974 151 Gene3D G3DSA:1.10.287.100 108 144 7.2E-6 T 28-03-2018 CU254_RS13380 209b464d825b4a9929ebc0aeda7f2974 151 SMART SM00347 29 129 1.5E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS28360 d521f8d834467d77231860b855684523 474 Gene3D G3DSA:3.50.50.60 1 394 1.5E-54 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS28360 d521f8d834467d77231860b855684523 474 Pfam PF01494 FAD binding domain 3 347 1.5E-68 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CU254_RS28360 d521f8d834467d77231860b855684523 474 SUPERFAMILY SSF51905 266 375 5.37E-59 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS28360 d521f8d834467d77231860b855684523 474 SUPERFAMILY SSF51905 3 170 5.37E-59 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS28360 d521f8d834467d77231860b855684523 474 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 279 294 7.3E-37 T 28-03-2018 CU254_RS28360 d521f8d834467d77231860b855684523 474 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 149 164 7.3E-37 T 28-03-2018 CU254_RS28360 d521f8d834467d77231860b855684523 474 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 7.3E-37 T 28-03-2018 CU254_RS28360 d521f8d834467d77231860b855684523 474 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 294 310 7.3E-37 T 28-03-2018 CU254_RS28360 d521f8d834467d77231860b855684523 474 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 312 330 7.3E-37 T 28-03-2018 CU254_RS18975 5b852258d0d204a1283b658faeaa8e7b 294 Pfam PF03466 LysR substrate binding domain 87 292 5.4E-32 T 28-03-2018 IPR005119 LysR, substrate-binding CU254_RS18975 5b852258d0d204a1283b658faeaa8e7b 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 8.4E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS18975 5b852258d0d204a1283b658faeaa8e7b 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 8.4E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS18975 5b852258d0d204a1283b658faeaa8e7b 294 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 8.4E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS18975 5b852258d0d204a1283b658faeaa8e7b 294 Gene3D G3DSA:3.40.190.10 88 175 3.6E-21 T 28-03-2018 CU254_RS18975 5b852258d0d204a1283b658faeaa8e7b 294 Gene3D G3DSA:3.40.190.10 176 266 3.3E-13 T 28-03-2018 CU254_RS18975 5b852258d0d204a1283b658faeaa8e7b 294 Gene3D G3DSA:1.10.10.10 1 85 9.3E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS18975 5b852258d0d204a1283b658faeaa8e7b 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 4.6E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS18975 5b852258d0d204a1283b658faeaa8e7b 294 SUPERFAMILY SSF46785 3 78 3.82E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS18975 5b852258d0d204a1283b658faeaa8e7b 294 SUPERFAMILY SSF53850 88 292 1.6E-28 T 28-03-2018 CU254_RS32945 82890e7cb48146d9ce425658a6e0ca77 267 Gene3D G3DSA:3.60.15.10 65 263 4.0E-18 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS32945 82890e7cb48146d9ce425658a6e0ca77 267 SUPERFAMILY SSF56281 58 244 4.76E-23 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS32945 82890e7cb48146d9ce425658a6e0ca77 267 SMART SM00849 73 242 8.7E-5 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS39150 196b4c76d60c874455392dfe74aad8da 532 Gene3D G3DSA:2.60.120.260 385 529 5.5E-8 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS39150 196b4c76d60c874455392dfe74aad8da 532 SUPERFAMILY SSF56112 31 218 2.29E-8 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS39150 196b4c76d60c874455392dfe74aad8da 532 Gene3D G3DSA:1.10.510.10 189 259 0.28 T 28-03-2018 CU254_RS39150 196b4c76d60c874455392dfe74aad8da 532 SUPERFAMILY SSF49785 402 520 6.38E-6 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS39150 196b4c76d60c874455392dfe74aad8da 532 Gene3D G3DSA:1.10.510.10 30 188 1.7E-6 T 28-03-2018 CU254_RS36125 0d92701f6966d5012cc2505130107a28 366 Gene3D G3DSA:1.10.260.40 25 65 1.4E-17 T 28-03-2018 CU254_RS36125 0d92701f6966d5012cc2505130107a28 366 SMART SM00354 10 81 2.1E-11 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CU254_RS36125 0d92701f6966d5012cc2505130107a28 366 Gene3D G3DSA:3.40.50.2300 184 333 1.4E-34 T 28-03-2018 CU254_RS36125 0d92701f6966d5012cc2505130107a28 366 Pfam PF13377 Periplasmic binding protein-like domain 178 352 1.6E-25 T 28-03-2018 CU254_RS36125 0d92701f6966d5012cc2505130107a28 366 Gene3D G3DSA:1.10.10.10 3 24 4.2E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS36125 0d92701f6966d5012cc2505130107a28 366 SUPERFAMILY SSF47413 10 68 2.95E-11 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS36125 0d92701f6966d5012cc2505130107a28 366 Pfam PF00356 Bacterial regulatory proteins, lacI family 13 54 4.5E-6 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CU254_RS36125 0d92701f6966d5012cc2505130107a28 366 SUPERFAMILY SSF53822 83 334 1.78E-40 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CU254_RS36125 0d92701f6966d5012cc2505130107a28 366 Gene3D G3DSA:3.40.50.2300 66 183 1.0E-25 T 28-03-2018 CU254_RS08295 0e2dba207481c30886d263f277efc52e 223 Gene3D G3DSA:2.40.100.10 57 222 3.5E-33 T 28-03-2018 IPR029000 Cyclophilin-like domain CU254_RS08295 0e2dba207481c30886d263f277efc52e 223 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 66 220 1.5E-21 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CU254_RS08295 0e2dba207481c30886d263f277efc52e 223 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 148 163 2.8E-6 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CU254_RS08295 0e2dba207481c30886d263f277efc52e 223 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 175 190 2.8E-6 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CU254_RS08295 0e2dba207481c30886d263f277efc52e 223 SUPERFAMILY SSF50891 66 221 8.44E-30 T 28-03-2018 IPR029000 Cyclophilin-like domain CU254_RS08295 0e2dba207481c30886d263f277efc52e 223 PIRSF PIRSF001467 54 206 4.9E-18 T 28-03-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 CU254_RS10600 f6c8581c8d27f4aedb19c547b1b97687 297 Gene3D G3DSA:3.40.50.1820 1 297 1.6E-52 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS10600 f6c8581c8d27f4aedb19c547b1b97687 297 Pfam PF07859 alpha/beta hydrolase fold 71 272 4.7E-54 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CU254_RS10600 f6c8581c8d27f4aedb19c547b1b97687 297 SUPERFAMILY SSF53474 59 295 4.22E-55 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS21955 915e8ad4773075a8e348d442ae7eb37b 474 SUPERFAMILY SSF50494 121 303 1.18E-36 T 28-03-2018 IPR009003 Peptidase S1, PA clan CU254_RS21955 915e8ad4773075a8e348d442ae7eb37b 474 Pfam PF13180 PDZ domain 382 465 2.3E-15 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CU254_RS21955 915e8ad4773075a8e348d442ae7eb37b 474 Pfam PF13365 Trypsin-like peptidase domain 149 294 2.2E-25 T 28-03-2018 CU254_RS21955 915e8ad4773075a8e348d442ae7eb37b 474 Gene3D G3DSA:2.30.42.10 379 471 3.0E-19 T 28-03-2018 CU254_RS21955 915e8ad4773075a8e348d442ae7eb37b 474 Gene3D G3DSA:2.40.10.10 117 216 3.1E-25 T 28-03-2018 CU254_RS21955 915e8ad4773075a8e348d442ae7eb37b 474 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 274 285 - T 28-03-2018 IPR033116 Serine proteases, trypsin family, serine active site CU254_RS21955 915e8ad4773075a8e348d442ae7eb37b 474 SMART SM00228 381 458 1.9E-12 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CU254_RS21955 915e8ad4773075a8e348d442ae7eb37b 474 PRINTS PR00834 HtrA/DegQ protease family signature 265 282 6.3E-20 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CU254_RS21955 915e8ad4773075a8e348d442ae7eb37b 474 PRINTS PR00834 HtrA/DegQ protease family signature 180 200 6.3E-20 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CU254_RS21955 915e8ad4773075a8e348d442ae7eb37b 474 PRINTS PR00834 HtrA/DegQ protease family signature 221 245 6.3E-20 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CU254_RS21955 915e8ad4773075a8e348d442ae7eb37b 474 PRINTS PR00834 HtrA/DegQ protease family signature 287 304 6.3E-20 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CU254_RS21955 915e8ad4773075a8e348d442ae7eb37b 474 PRINTS PR00834 HtrA/DegQ protease family signature 158 170 6.3E-20 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CU254_RS21955 915e8ad4773075a8e348d442ae7eb37b 474 Gene3D G3DSA:2.40.10.10 217 365 1.9E-24 T 28-03-2018 CU254_RS21955 915e8ad4773075a8e348d442ae7eb37b 474 SUPERFAMILY SSF50156 398 471 8.68E-17 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CU254_RS36510 388132fdf4b3b1da5840af7a2886dc75 206 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 25 179 2.5E-10 T 28-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal CU254_RS36510 388132fdf4b3b1da5840af7a2886dc75 206 SMART SM00943 22 188 2.3E-4 T 28-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal CU254_RS40115 07c06a440d619c1e57cd7a7627a63199 207 SMART SM00506 48 192 6.4E-10 T 28-03-2018 IPR002589 Macro domain CU254_RS40115 07c06a440d619c1e57cd7a7627a63199 207 SUPERFAMILY SSF52949 45 201 1.23E-23 T 28-03-2018 CU254_RS40115 07c06a440d619c1e57cd7a7627a63199 207 Gene3D G3DSA:3.40.220.10 36 206 5.4E-25 T 28-03-2018 CU254_RS40115 07c06a440d619c1e57cd7a7627a63199 207 Pfam PF01661 Macro domain 65 190 1.7E-10 T 28-03-2018 IPR002589 Macro domain CU254_RS36025 cac2eb7a0cffd93c52dce6935c3c9112 216 SUPERFAMILY SSF53639 3 215 4.12E-62 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CU254_RS36025 cac2eb7a0cffd93c52dce6935c3c9112 216 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 9 187 3.1E-46 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CU254_RS36025 cac2eb7a0cffd93c52dce6935c3c9112 216 SMART SM01007 8 187 1.4E-57 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CU254_RS36025 cac2eb7a0cffd93c52dce6935c3c9112 216 Gene3D G3DSA:3.40.225.10 1 216 4.3E-63 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CU254_RS14245 2d4e7eb6747faf6e2354b9524810690a 138 Gene3D G3DSA:3.30.750.24 18 119 2.4E-11 T 28-03-2018 IPR002645 STAS domain CU254_RS14245 2d4e7eb6747faf6e2354b9524810690a 138 Pfam PF01740 STAS domain 21 111 1.5E-5 T 28-03-2018 IPR002645 STAS domain CU254_RS14245 2d4e7eb6747faf6e2354b9524810690a 138 SUPERFAMILY SSF52091 21 116 8.24E-12 T 28-03-2018 IPR002645 STAS domain CU254_RS40710 0e5cd2f45424bef52e48148bae94a670 305 SUPERFAMILY SSF52540 5 223 4.51E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS40710 0e5cd2f45424bef52e48148bae94a670 305 Pfam PF00005 ABC transporter 23 160 1.0E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS40710 0e5cd2f45424bef52e48148bae94a670 305 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS40710 0e5cd2f45424bef52e48148bae94a670 305 SMART SM00382 31 209 1.0E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS40710 0e5cd2f45424bef52e48148bae94a670 305 Gene3D G3DSA:3.40.50.300 3 278 3.6E-63 T 28-03-2018 CU254_RS29525 667923ed541ee42b7958d62b72631f12 435 Gene3D G3DSA:3.40.50.1820 46 415 4.8E-9 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS29525 667923ed541ee42b7958d62b72631f12 435 Pfam PF03583 Secretory lipase 128 414 6.6E-48 T 28-03-2018 IPR005152 Lipase, secreted GO:0004806|GO:0016042 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 CU254_RS29525 667923ed541ee42b7958d62b72631f12 435 PIRSF PIRSF029171 1 418 1.6E-17 T 28-03-2018 IPR005152 Lipase, secreted GO:0004806|GO:0016042 KEGG: 00561+3.1.1.3|MetaCyc: PWY-6857 CU254_RS29525 667923ed541ee42b7958d62b72631f12 435 SUPERFAMILY SSF53474 134 237 1.39E-6 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS29525 667923ed541ee42b7958d62b72631f12 435 SUPERFAMILY SSF53474 318 409 1.39E-6 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS37045 4a4efa7c8fd9147019454a2f7f2818ef 174 SUPERFAMILY SSF52540 13 152 1.46E-10 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS37045 4a4efa7c8fd9147019454a2f7f2818ef 174 Gene3D G3DSA:3.40.50.300 2 171 1.8E-14 T 28-03-2018 CU254_RS06020 7a58ebae317ee7e56c7d37ea7fe4be8a 388 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 274 355 4.8E-12 T 28-03-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 Reactome: R-HSA-156588 CU254_RS06020 7a58ebae317ee7e56c7d37ea7fe4be8a 388 Gene3D G3DSA:3.40.50.2000 229 372 1.6E-35 T 28-03-2018 CU254_RS06020 7a58ebae317ee7e56c7d37ea7fe4be8a 388 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 14 387 3.8E-106 T 28-03-2018 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 CU254_RS06020 7a58ebae317ee7e56c7d37ea7fe4be8a 388 Gene3D G3DSA:3.40.50.2000 4 228 5.4E-28 T 28-03-2018 CU254_RS06020 7a58ebae317ee7e56c7d37ea7fe4be8a 388 SUPERFAMILY SSF53756 1 387 4.54E-71 T 28-03-2018 CU254_RS12540 38ba5ee6eb37338b2e008185c0e185d2 460 Pfam PF07687 Peptidase dimerisation domain 202 358 6.8E-13 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CU254_RS12540 38ba5ee6eb37338b2e008185c0e185d2 460 Pfam PF01546 Peptidase family M20/M25/M40 92 454 1.3E-30 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CU254_RS12540 38ba5ee6eb37338b2e008185c0e185d2 460 Gene3D G3DSA:3.40.630.10 17 207 3.6E-35 T 28-03-2018 CU254_RS12540 38ba5ee6eb37338b2e008185c0e185d2 460 Gene3D G3DSA:3.30.70.360 208 365 1.3E-36 T 28-03-2018 CU254_RS12540 38ba5ee6eb37338b2e008185c0e185d2 460 SUPERFAMILY SSF53187 16 204 2.31E-54 T 28-03-2018 CU254_RS12540 38ba5ee6eb37338b2e008185c0e185d2 460 SUPERFAMILY SSF53187 371 458 2.31E-54 T 28-03-2018 CU254_RS33310 ee9e3c0dc2f27ead5e56eb5ae3933627 284 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 103 108 - T 28-03-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 CU254_RS33310 ee9e3c0dc2f27ead5e56eb5ae3933627 284 Gene3D G3DSA:2.40.10.10 55 101 2.0E-8 T 28-03-2018 CU254_RS33310 ee9e3c0dc2f27ead5e56eb5ae3933627 284 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 229 241 2.2E-10 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CU254_RS33310 ee9e3c0dc2f27ead5e56eb5ae3933627 284 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 93 108 2.2E-10 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CU254_RS33310 ee9e3c0dc2f27ead5e56eb5ae3933627 284 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 150 164 2.2E-10 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CU254_RS33310 ee9e3c0dc2f27ead5e56eb5ae3933627 284 Pfam PF00089 Trypsin 69 278 8.7E-24 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CU254_RS33310 ee9e3c0dc2f27ead5e56eb5ae3933627 284 SMART SM00020 37 278 1.8E-8 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CU254_RS33310 ee9e3c0dc2f27ead5e56eb5ae3933627 284 Gene3D G3DSA:2.40.10.10 102 284 1.8E-29 T 28-03-2018 CU254_RS33310 ee9e3c0dc2f27ead5e56eb5ae3933627 284 SUPERFAMILY SSF50494 86 283 2.06E-32 T 28-03-2018 IPR009003 Peptidase S1, PA clan CU254_RS09480 5dcafddccca0afc7a974dd00d3dae335 166 Pfam PF13302 Acetyltransferase (GNAT) domain 11 146 2.3E-21 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS09480 5dcafddccca0afc7a974dd00d3dae335 166 SUPERFAMILY SSF55729 4 152 7.15E-23 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS09480 5dcafddccca0afc7a974dd00d3dae335 166 Gene3D G3DSA:3.40.630.30 2 165 3.4E-18 T 28-03-2018 CU254_RS40845 0c38ab4a93942ad6c09399500a0b06e1 299 Pfam PF00005 ABC transporter 20 159 3.9E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS40845 0c38ab4a93942ad6c09399500a0b06e1 299 Gene3D G3DSA:3.40.50.300 1 270 2.5E-59 T 28-03-2018 CU254_RS40845 0c38ab4a93942ad6c09399500a0b06e1 299 SUPERFAMILY SSF52540 4 219 5.53E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS40845 0c38ab4a93942ad6c09399500a0b06e1 299 SMART SM00382 29 207 1.0E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS40845 0c38ab4a93942ad6c09399500a0b06e1 299 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS04200 dffb413d867698f87ee772de14e243a1 421 PRINTS PR00732 Glycosyl hydrolase family 4 signature 92 105 7.1E-27 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CU254_RS04200 dffb413d867698f87ee772de14e243a1 421 PRINTS PR00732 Glycosyl hydrolase family 4 signature 2 17 7.1E-27 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CU254_RS04200 dffb413d867698f87ee772de14e243a1 421 PRINTS PR00732 Glycosyl hydrolase family 4 signature 71 87 7.1E-27 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CU254_RS04200 dffb413d867698f87ee772de14e243a1 421 PRINTS PR00732 Glycosyl hydrolase family 4 signature 106 126 7.1E-27 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CU254_RS04200 dffb413d867698f87ee772de14e243a1 421 PRINTS PR00732 Glycosyl hydrolase family 4 signature 160 171 7.1E-27 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CU254_RS04200 dffb413d867698f87ee772de14e243a1 421 PRINTS PR00732 Glycosyl hydrolase family 4 signature 186 198 7.1E-27 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CU254_RS04200 dffb413d867698f87ee772de14e243a1 421 Pfam PF02056 Family 4 glycosyl hydrolase 2 180 4.1E-41 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CU254_RS04200 dffb413d867698f87ee772de14e243a1 421 Gene3D G3DSA:3.40.50.720 1 155 1.5E-25 T 28-03-2018 CU254_RS04200 dffb413d867698f87ee772de14e243a1 421 Gene3D G3DSA:3.90.110.10 156 419 2.1E-88 T 28-03-2018 CU254_RS04200 dffb413d867698f87ee772de14e243a1 421 SUPERFAMILY SSF56327 166 417 1.73E-59 T 28-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CU254_RS04200 dffb413d867698f87ee772de14e243a1 421 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 191 395 1.6E-40 T 28-03-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 CU254_RS04200 dffb413d867698f87ee772de14e243a1 421 SUPERFAMILY SSF51735 1 157 1.79E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS37190 5168524a6092532a30a8a1440fb7abfb 993 Pfam PF00801 PKD domain 425 483 2.0E-9 T 28-03-2018 IPR000601 PKD domain CU254_RS37190 5168524a6092532a30a8a1440fb7abfb 993 SMART SM00089 414 493 1.9E-11 T 28-03-2018 IPR022409 PKD/Chitinase domain CU254_RS37190 5168524a6092532a30a8a1440fb7abfb 993 Gene3D G3DSA:2.60.40.10 497 590 8.8E-13 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS37190 5168524a6092532a30a8a1440fb7abfb 993 SUPERFAMILY SSF50952 33 409 1.96E-19 T 28-03-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 CU254_RS37190 5168524a6092532a30a8a1440fb7abfb 993 Gene3D G3DSA:2.120.10.30 25 430 2.6E-50 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CU254_RS37190 5168524a6092532a30a8a1440fb7abfb 993 Pfam PF08310 LGFP repeat 797 848 3.5E-24 T 28-03-2018 IPR013207 LGFP CU254_RS37190 5168524a6092532a30a8a1440fb7abfb 993 Pfam PF08310 LGFP repeat 849 902 1.5E-25 T 28-03-2018 IPR013207 LGFP CU254_RS37190 5168524a6092532a30a8a1440fb7abfb 993 Pfam PF08310 LGFP repeat 904 956 2.0E-24 T 28-03-2018 IPR013207 LGFP CU254_RS37190 5168524a6092532a30a8a1440fb7abfb 993 Pfam PF08310 LGFP repeat 738 795 1.1E-20 T 28-03-2018 IPR013207 LGFP CU254_RS37190 5168524a6092532a30a8a1440fb7abfb 993 Pfam PF08310 LGFP repeat 686 734 3.1E-10 T 28-03-2018 IPR013207 LGFP CU254_RS37190 5168524a6092532a30a8a1440fb7abfb 993 Gene3D G3DSA:3.40.1850.10 431 496 9.5E-13 T 28-03-2018 CU254_RS37190 5168524a6092532a30a8a1440fb7abfb 993 SUPERFAMILY SSF49299 410 488 1.07E-13 T 28-03-2018 IPR000601 PKD domain CU254_RS37190 5168524a6092532a30a8a1440fb7abfb 993 Pfam PF07995 Glucose / Sorbosone dehydrogenase 58 392 3.9E-35 T 28-03-2018 IPR012938 Glucose/Sorbosone dehydrogenase CU254_RS28995 e0e3239e93978dad817192c5d321912a 112 Gene3D G3DSA:1.10.10.10 5 107 1.1E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS28995 e0e3239e93978dad817192c5d321912a 112 SUPERFAMILY SSF46785 11 95 2.14E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS28995 e0e3239e93978dad817192c5d321912a 112 Pfam PF03551 Transcriptional regulator PadR-like family 13 86 3.2E-19 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CU254_RS06475 afb9b6846cbf8305c9cbf3ceca181f6c 482 Pfam PF04228 Putative neutral zinc metallopeptidase 67 261 4.6E-12 T 28-03-2018 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative CU254_RS06475 afb9b6846cbf8305c9cbf3ceca181f6c 482 Gene3D G3DSA:3.40.190.10 1 96 0.0011 T 28-03-2018 CU254_RS06475 afb9b6846cbf8305c9cbf3ceca181f6c 482 SUPERFAMILY SSF55486 63 203 4.87E-8 T 28-03-2018 CU254_RS17660 c8444a2062c92aa9ff0ad0d2535510b8 174 Gene3D G3DSA:2.60.120.10 9 174 1.9E-42 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS17660 c8444a2062c92aa9ff0ad0d2535510b8 174 SUPERFAMILY SSF51182 4 173 1.45E-53 T 28-03-2018 IPR011051 RmlC-like cupin domain CU254_RS17660 c8444a2062c92aa9ff0ad0d2535510b8 174 TIGRFAM TIGR03037 anthran_nbaC: 3-hydroxyanthranilate 3,4-dioxygenase 8 168 3.9E-66 T 28-03-2018 IPR010329 3-hydroxyanthranilic acid dioxygenase GO:0000334|GO:0005506|GO:0055114 KEGG: 00380+1.13.11.6|MetaCyc: PWY-5647|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-6505|Reactome: R-HSA-71240 CU254_RS17660 c8444a2062c92aa9ff0ad0d2535510b8 174 Pfam PF06052 3-hydroxyanthranilic acid dioxygenase 8 155 2.5E-47 T 28-03-2018 IPR010329 3-hydroxyanthranilic acid dioxygenase GO:0000334|GO:0005506|GO:0055114 KEGG: 00380+1.13.11.6|MetaCyc: PWY-5647|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-6505|Reactome: R-HSA-71240 CU254_RS17660 c8444a2062c92aa9ff0ad0d2535510b8 174 Hamap MF_00825 3-hydroxyanthranilate 3,4-dioxygenase [nbaC]. 4 173 32.27 T 28-03-2018 IPR010329 3-hydroxyanthranilic acid dioxygenase GO:0000334|GO:0005506|GO:0055114 KEGG: 00380+1.13.11.6|MetaCyc: PWY-5647|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-6505|Reactome: R-HSA-71240 CU254_RS12015 68941047a452dbd07674e34298c51fd6 564 Pfam PF07287 Acyclic terpene utilisation family protein AtuA 7 333 5.2E-130 T 28-03-2018 IPR010839 Acyclic terpene utilisation CU254_RS42080 7869b9e3b710723810d3ead05655ce71 687 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 39 283 9.4E-44 T 28-03-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 CU254_RS42080 7869b9e3b710723810d3ead05655ce71 687 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 312 510 1.8E-22 T 28-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CU254_RS42080 7869b9e3b710723810d3ead05655ce71 687 Gene3D G3DSA:3.40.50.1820 6 331 3.5E-45 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS42080 7869b9e3b710723810d3ead05655ce71 687 SUPERFAMILY SSF53474 17 337 1.59E-54 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS42080 7869b9e3b710723810d3ead05655ce71 687 SMART SM00939 300 522 1.4E-30 T 28-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CU254_RS42080 7869b9e3b710723810d3ead05655ce71 687 Gene3D G3DSA:2.60.120.260 332 521 1.7E-23 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS42080 7869b9e3b710723810d3ead05655ce71 687 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 39 508 1.4E-68 T 28-03-2018 IPR005674 CocE/Serine esterase GO:0016787 CU254_RS42080 7869b9e3b710723810d3ead05655ce71 687 SUPERFAMILY SSF49785 330 512 5.31E-24 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS21145 6d1019d951cb93beb9d4a6a75e37513d 281 Pfam PF00296 Luciferase-like monooxygenase 11 277 1.4E-37 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS21145 6d1019d951cb93beb9d4a6a75e37513d 281 Gene3D G3DSA:3.20.20.30 7 281 1.4E-64 T 28-03-2018 CU254_RS21145 6d1019d951cb93beb9d4a6a75e37513d 281 SUPERFAMILY SSF51679 8 278 9.55E-54 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS19135 9695857f93d8d15304c96a9e16d2b763 279 SUPERFAMILY SSF53474 8 277 3.78E-40 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS19135 9695857f93d8d15304c96a9e16d2b763 279 Gene3D G3DSA:3.40.50.1820 5 279 5.0E-35 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS19135 9695857f93d8d15304c96a9e16d2b763 279 Pfam PF00561 alpha/beta hydrolase fold 22 261 7.3E-13 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS20230 5cd12d5f89414bd2023fc30cbfce160b 156 Gene3D G3DSA:2.60.200.20 25 147 6.8E-31 T 28-03-2018 CU254_RS20230 5cd12d5f89414bd2023fc30cbfce160b 156 SMART SM00240 74 124 2.8E-17 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CU254_RS20230 5cd12d5f89414bd2023fc30cbfce160b 156 SUPERFAMILY SSF49879 32 145 2.1E-32 T 28-03-2018 IPR008984 SMAD/FHA domain GO:0005515 CU254_RS20230 5cd12d5f89414bd2023fc30cbfce160b 156 Pfam PF00498 FHA domain 76 138 6.8E-19 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CU254_RS16170 4e1f85363fc4ef079d86572b618eb69f 239 SUPERFAMILY SSF56784 6 209 1.4E-17 T 28-03-2018 IPR023214 HAD-like domain CU254_RS16170 4e1f85363fc4ef079d86572b618eb69f 239 Pfam PF12710 haloacid dehalogenase-like hydrolase 9 190 5.2E-13 T 28-03-2018 CU254_RS16170 4e1f85363fc4ef079d86572b618eb69f 239 Gene3D G3DSA:3.40.50.1000 3 229 1.5E-14 T 28-03-2018 IPR023214 HAD-like domain CU254_RS35805 de4a0814a0b2467ceba386d9ea4d2489 274 Pfam PF13622 Thioesterase-like superfamily 28 270 5.1E-61 T 28-03-2018 CU254_RS35805 de4a0814a0b2467ceba386d9ea4d2489 274 Gene3D G3DSA:3.10.129.10 6 119 1.4E-38 T 28-03-2018 CU254_RS35805 de4a0814a0b2467ceba386d9ea4d2489 274 SUPERFAMILY SSF54637 120 272 9.21E-44 T 28-03-2018 IPR029069 HotDog domain CU254_RS35805 de4a0814a0b2467ceba386d9ea4d2489 274 SUPERFAMILY SSF54637 9 115 3.13E-37 T 28-03-2018 IPR029069 HotDog domain CU254_RS35805 de4a0814a0b2467ceba386d9ea4d2489 274 Gene3D G3DSA:3.10.129.10 137 274 3.2E-44 T 28-03-2018 CU254_RS17310 17124f515ec26a88d90482b4be48b8ac 286 Gene3D G3DSA:3.40.50.150 4 138 6.9E-30 T 28-03-2018 CU254_RS17310 17124f515ec26a88d90482b4be48b8ac 286 Gene3D G3DSA:2.70.160.11 143 286 2.0E-7 T 28-03-2018 CU254_RS17310 17124f515ec26a88d90482b4be48b8ac 286 SUPERFAMILY SSF53335 9 246 3.53E-37 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS17310 17124f515ec26a88d90482b4be48b8ac 286 Pfam PF13649 Methyltransferase domain 36 133 1.7E-8 T 28-03-2018 CU254_RS29705 61d4de9fada58eff5a4e527c19c75414 289 SUPERFAMILY SSF51430 14 287 8.9E-63 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS29705 61d4de9fada58eff5a4e527c19c75414 289 PRINTS PR00069 Aldo-keto reductase signature 221 245 3.8E-6 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CU254_RS29705 61d4de9fada58eff5a4e527c19c75414 289 PRINTS PR00069 Aldo-keto reductase signature 151 168 3.8E-6 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CU254_RS29705 61d4de9fada58eff5a4e527c19c75414 289 PRINTS PR00069 Aldo-keto reductase signature 49 73 3.8E-6 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CU254_RS29705 61d4de9fada58eff5a4e527c19c75414 289 Pfam PF00248 Aldo/keto reductase family 19 287 7.3E-47 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS29705 61d4de9fada58eff5a4e527c19c75414 289 Gene3D G3DSA:3.20.20.100 9 289 8.5E-64 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS12845 1a580f1155f852939980a1abddbe2299 77 Gene3D G3DSA:2.40.50.100 47 77 3.2E-6 T 28-03-2018 CU254_RS12845 1a580f1155f852939980a1abddbe2299 77 Gene3D G3DSA:3.90.1170.30 1 46 7.3E-13 T 28-03-2018 CU254_RS12845 1a580f1155f852939980a1abddbe2299 77 SUPERFAMILY SSF51230 2 76 3.27E-25 T 28-03-2018 IPR011053 Single hybrid motif CU254_RS12845 1a580f1155f852939980a1abddbe2299 77 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 26 55 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CU254_RS12845 1a580f1155f852939980a1abddbe2299 77 Pfam PF00364 Biotin-requiring enzyme 3 75 3.3E-22 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CU254_RS26040 04ca946acb85dedf6f346a52bea35f44 403 Gene3D G3DSA:1.10.260.40 3 85 3.9E-19 T 28-03-2018 CU254_RS26040 04ca946acb85dedf6f346a52bea35f44 403 Pfam PF06114 IrrE N-terminal-like domain 175 301 3.1E-16 T 28-03-2018 IPR010359 IrrE N-terminal-like domain CU254_RS26040 04ca946acb85dedf6f346a52bea35f44 403 SUPERFAMILY SSF47413 14 79 1.1E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS26040 04ca946acb85dedf6f346a52bea35f44 403 Pfam PF01381 Helix-turn-helix 20 72 5.7E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS26040 04ca946acb85dedf6f346a52bea35f44 403 SMART SM00530 19 74 1.1E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS01975 00945b112c2cfcea156e6600ba125e8d 137 ProSitePatterns PS00464 Ribosomal protein L22 signature. 97 121 - T 28-03-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS01975 00945b112c2cfcea156e6600ba125e8d 137 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 19 121 7.9E-44 T 28-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS01975 00945b112c2cfcea156e6600ba125e8d 137 SUPERFAMILY SSF54843 12 124 3.01E-40 T 28-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 CU254_RS01975 00945b112c2cfcea156e6600ba125e8d 137 Gene3D G3DSA:3.90.470.10 1 137 4.2E-44 T 28-03-2018 CU254_RS01975 00945b112c2cfcea156e6600ba125e8d 137 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 15 124 28.398 T 28-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS01975 00945b112c2cfcea156e6600ba125e8d 137 Pfam PF00237 Ribosomal protein L22p/L17e 19 121 1.8E-33 T 28-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 CU254_RS05010 035e433de4ee6d6fc761295fbea58bf6 169 Pfam PF07291 Methylamine utilisation protein MauE 7 104 4.3E-10 T 28-03-2018 IPR009908 Methylamine utilisation protein, MauE GO:0016021|GO:0030416 CU254_RS08530 f3397dc429cafdcf9ee2cdcdb3f594d4 189 Gene3D G3DSA:1.10.357.10 63 189 4.7E-22 T 28-03-2018 CU254_RS08530 f3397dc429cafdcf9ee2cdcdb3f594d4 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 64 1.0E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS08530 f3397dc429cafdcf9ee2cdcdb3f594d4 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 3.7E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS08530 f3397dc429cafdcf9ee2cdcdb3f594d4 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 3.7E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS08530 f3397dc429cafdcf9ee2cdcdb3f594d4 189 SUPERFAMILY SSF46689 7 81 1.15E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS08530 f3397dc429cafdcf9ee2cdcdb3f594d4 189 Gene3D G3DSA:1.10.10.60 1 62 2.7E-22 T 28-03-2018 CU254_RS03590 5c072710e621f44ffdbe9ef65667a858 330 SUPERFAMILY SSF142338 3 325 5.49E-82 T 28-03-2018 CU254_RS03590 5c072710e621f44ffdbe9ef65667a858 330 Gene3D G3DSA:1.10.8.240 46 119 4.2E-39 T 28-03-2018 CU254_RS03590 5c072710e621f44ffdbe9ef65667a858 330 Hamap MF_01257 2-phospho-L-lactate transferase [cofD]. 1 330 135.743 T 28-03-2018 IPR010115 2-phospho-L-lactate transferase GO:0000287|GO:0016780|GO:0051188 KEGG: 00680+2.7.8.28|MetaCyc: PWY-5198 CU254_RS03590 5c072710e621f44ffdbe9ef65667a858 330 TIGRFAM TIGR01819 F420_cofD: 2-phospho-L-lactate transferase 3 322 8.4E-119 T 28-03-2018 IPR010115 2-phospho-L-lactate transferase GO:0000287|GO:0016780|GO:0051188 KEGG: 00680+2.7.8.28|MetaCyc: PWY-5198 CU254_RS03590 5c072710e621f44ffdbe9ef65667a858 330 Pfam PF01933 Uncharacterised protein family UPF0052 3 290 7.2E-65 T 28-03-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 CU254_RS03590 5c072710e621f44ffdbe9ef65667a858 330 Gene3D G3DSA:3.40.50.10680 120 329 3.8E-44 T 28-03-2018 CU254_RS12950 387c7eec701fd0447025c1738f48cd46 2362 Gene3D G3DSA:1.10.1200.10 953 1017 3.3E-22 T 28-03-2018 CU254_RS12950 387c7eec701fd0447025c1738f48cd46 2362 Gene3D G3DSA:3.30.559.10 21 240 6.7E-41 T 28-03-2018 CU254_RS12950 387c7eec701fd0447025c1738f48cd46 2362 Gene3D G3DSA:3.30.559.10 1018 1222 2.0E-38 T 28-03-2018 CU254_RS12950 387c7eec701fd0447025c1738f48cd46 2362 SUPERFAMILY SSF52777 38 216 1.22E-46 T 28-03-2018 CU254_RS12950 387c7eec701fd0447025c1738f48cd46 2362 Pfam PF00550 Phosphopantetheine attachment site 1924 1984 2.7E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS12950 387c7eec701fd0447025c1738f48cd46 2362 Pfam PF00550 Phosphopantetheine attachment site 949 1010 5.6E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS12950 387c7eec701fd0447025c1738f48cd46 2362 Gene3D G3DSA:3.40.50.980 486 594 1.3E-27 T 28-03-2018 CU254_RS12950 387c7eec701fd0447025c1738f48cd46 2362 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1594 1605 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS12950 387c7eec701fd0447025c1738f48cd46 2362 SUPERFAMILY SSF56801 478 960 6.93E-148 T 28-03-2018 CU254_RS12950 387c7eec701fd0447025c1738f48cd46 2362 ProSitePatterns PS00455 Putative AMP-binding domain signature. 610 621 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS12950 387c7eec701fd0447025c1738f48cd46 2362 Gene3D G3DSA:3.30.559.10 1981 2154 7.6E-14 T 28-03-2018 CU254_RS12950 387c7eec701fd0447025c1738f48cd46 2362 Gene3D G3DSA:3.40.50.980 1600 1743 1.3E-35 T 28-03-2018 CU254_RS12950 387c7eec701fd0447025c1738f48cd46 2362 Pfam PF00501 AMP-binding enzyme 493 850 1.8E-88 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS12950 387c7eec701fd0447025c1738f48cd46 2362 Pfam PF00501 AMP-binding enzyme 1477 1573 3.7E-23 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS12950 387c7eec701fd0447025c1738f48cd46 2362 Pfam PF00501 AMP-binding enzyme 1582 1829 4.2E-65 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS12950 387c7eec701fd0447025c1738f48cd46 2362 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1946 1961 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CU254_RS12950 387c7eec701fd0447025c1738f48cd46 2362 Gene3D G3DSA:3.40.50.980 595 765 2.2E-48 T 28-03-2018 CU254_RS12950 387c7eec701fd0447025c1738f48cd46 2362 SUPERFAMILY SSF47336 941 1013 2.09E-18 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS12950 387c7eec701fd0447025c1738f48cd46 2362 Gene3D G3DSA:3.30.300.30 845 952 1.1E-30 T 28-03-2018 CU254_RS12950 387c7eec701fd0447025c1738f48cd46 2362 Gene3D G3DSA:3.30.300.30 1824 1928 1.8E-28 T 28-03-2018 CU254_RS12950 387c7eec701fd0447025c1738f48cd46 2362 SUPERFAMILY SSF52777 2143 2333 5.67E-13 T 28-03-2018 CU254_RS12950 387c7eec701fd0447025c1738f48cd46 2362 ProSitePatterns PS00012 Phosphopantetheine attachment site. 971 986 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CU254_RS12950 387c7eec701fd0447025c1738f48cd46 2362 SUPERFAMILY SSF56801 1467 1934 1.44E-145 T 28-03-2018 CU254_RS12950 387c7eec701fd0447025c1738f48cd46 2362 SUPERFAMILY SSF47336 1916 1984 1.57E-18 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS12950 387c7eec701fd0447025c1738f48cd46 2362 SUPERFAMILY SSF52777 2011 2142 7.89E-16 T 28-03-2018 CU254_RS12950 387c7eec701fd0447025c1738f48cd46 2362 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1585 1853 2.9E-95 T 28-03-2018 IPR010071 Amino acid adenylation domain CU254_RS12950 387c7eec701fd0447025c1738f48cd46 2362 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 599 874 9.4E-99 T 28-03-2018 IPR010071 Amino acid adenylation domain CU254_RS12950 387c7eec701fd0447025c1738f48cd46 2362 SMART SM00823 Phosphopantetheine attachment site 1922 1990 7.6E-5 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS12950 387c7eec701fd0447025c1738f48cd46 2362 SMART SM00823 Phosphopantetheine attachment site 944 1016 6.2E-6 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS12950 387c7eec701fd0447025c1738f48cd46 2362 SUPERFAMILY SSF52777 1033 1193 3.34E-44 T 28-03-2018 CU254_RS12950 387c7eec701fd0447025c1738f48cd46 2362 Gene3D G3DSA:1.10.1200.10 1929 1980 8.4E-22 T 28-03-2018 CU254_RS12950 387c7eec701fd0447025c1738f48cd46 2362 Pfam PF00668 Condensation domain 2011 2168 4.2E-10 T 28-03-2018 IPR001242 Condensation domain CU254_RS12950 387c7eec701fd0447025c1738f48cd46 2362 Pfam PF00668 Condensation domain 33 473 5.6E-97 T 28-03-2018 IPR001242 Condensation domain CU254_RS12950 387c7eec701fd0447025c1738f48cd46 2362 Pfam PF00668 Condensation domain 1031 1458 1.9E-83 T 28-03-2018 IPR001242 Condensation domain CU254_RS12950 387c7eec701fd0447025c1738f48cd46 2362 SUPERFAMILY SSF52777 222 468 2.0E-61 T 28-03-2018 CU254_RS12950 387c7eec701fd0447025c1738f48cd46 2362 SUPERFAMILY SSF52777 1207 1446 1.07E-61 T 28-03-2018 CU254_RS12950 387c7eec701fd0447025c1738f48cd46 2362 Gene3D G3DSA:2.30.38.10 1744 1819 9.5E-24 T 28-03-2018 CU254_RS12950 387c7eec701fd0447025c1738f48cd46 2362 Gene3D G3DSA:2.30.38.10 766 840 3.7E-26 T 28-03-2018 CU254_RS12950 387c7eec701fd0447025c1738f48cd46 2362 Gene3D G3DSA:3.40.50.980 1469 1599 7.5E-39 T 28-03-2018 CU254_RS12950 387c7eec701fd0447025c1738f48cd46 2362 Pfam PF13193 AMP-binding enzyme C-terminal domain 858 924 7.5E-7 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS12950 387c7eec701fd0447025c1738f48cd46 2362 Pfam PF13193 AMP-binding enzyme C-terminal domain 1837 1897 2.2E-6 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS24750 b388831abbe908a25cf7cd56f73a4b75 1400 SMART SM00382 1172 1312 2.7E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS24750 b388831abbe908a25cf7cd56f73a4b75 1400 SMART SM00382 615 753 1.4E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS24750 b388831abbe908a25cf7cd56f73a4b75 1400 SMART SM00382 893 1031 1.5E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS24750 b388831abbe908a25cf7cd56f73a4b75 1400 SUPERFAMILY SSF52540 856 1096 6.0E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS24750 b388831abbe908a25cf7cd56f73a4b75 1400 PRINTS PR00819 CbxX/CfqX superfamily signature 934 948 8.3E-50 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CU254_RS24750 b388831abbe908a25cf7cd56f73a4b75 1400 PRINTS PR00819 CbxX/CfqX superfamily signature 896 911 8.3E-50 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CU254_RS24750 b388831abbe908a25cf7cd56f73a4b75 1400 PRINTS PR00819 CbxX/CfqX superfamily signature 999 1016 8.3E-50 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CU254_RS24750 b388831abbe908a25cf7cd56f73a4b75 1400 PRINTS PR00819 CbxX/CfqX superfamily signature 1016 1035 8.3E-50 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CU254_RS24750 b388831abbe908a25cf7cd56f73a4b75 1400 PRINTS PR00819 CbxX/CfqX superfamily signature 948 967 8.3E-50 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CU254_RS24750 b388831abbe908a25cf7cd56f73a4b75 1400 PRINTS PR00819 CbxX/CfqX superfamily signature 1073 1085 8.3E-50 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CU254_RS24750 b388831abbe908a25cf7cd56f73a4b75 1400 PRINTS PR00819 CbxX/CfqX superfamily signature 856 870 8.3E-50 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CU254_RS24750 b388831abbe908a25cf7cd56f73a4b75 1400 PRINTS PR00819 CbxX/CfqX superfamily signature 978 990 8.3E-50 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CU254_RS24750 b388831abbe908a25cf7cd56f73a4b75 1400 SUPERFAMILY SSF52540 1136 1376 1.01E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS24750 b388831abbe908a25cf7cd56f73a4b75 1400 Gene3D G3DSA:3.40.50.300 1121 1309 4.0E-22 T 28-03-2018 CU254_RS24750 b388831abbe908a25cf7cd56f73a4b75 1400 Gene3D G3DSA:3.40.50.300 842 1028 1.1E-24 T 28-03-2018 CU254_RS24750 b388831abbe908a25cf7cd56f73a4b75 1400 Gene3D G3DSA:3.40.50.300 561 750 1.3E-23 T 28-03-2018 CU254_RS24750 b388831abbe908a25cf7cd56f73a4b75 1400 SUPERFAMILY SSF52540 578 791 3.08E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS24750 b388831abbe908a25cf7cd56f73a4b75 1400 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 897 1028 3.0E-14 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CU254_RS24750 b388831abbe908a25cf7cd56f73a4b75 1400 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 1177 1304 1.8E-14 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CU254_RS24750 b388831abbe908a25cf7cd56f73a4b75 1400 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 619 750 2.4E-15 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CU254_RS24750 b388831abbe908a25cf7cd56f73a4b75 1400 Gene3D G3DSA:3.40.50.300 316 522 0.0012 T 28-03-2018 CU254_RS22270 283c243af3ec201d968865c94c0dfefc 396 Pfam PF00999 Sodium/hydrogen exchanger family 13 371 1.1E-48 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CU254_RS22270 283c243af3ec201d968865c94c0dfefc 396 Gene3D G3DSA:1.20.91.10 229 316 2.4E-9 T 28-03-2018 CU254_RS28260 a2028dbd17d7430b44a9e08dab1420c3 450 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 78 415 2.7E-43 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CU254_RS28260 a2028dbd17d7430b44a9e08dab1420c3 450 SUPERFAMILY SSF53686 28 426 3.14E-109 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CU254_RS28260 a2028dbd17d7430b44a9e08dab1420c3 450 PIRSF PIRSF500824 2 437 1.6E-198 T 28-03-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CU254_RS28260 a2028dbd17d7430b44a9e08dab1420c3 450 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 106 120 - T 28-03-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CU254_RS28260 a2028dbd17d7430b44a9e08dab1420c3 450 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 22 428 39.389 T 28-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CU254_RS28260 a2028dbd17d7430b44a9e08dab1420c3 450 TIGRFAM TIGR01415 trpB_rel: pyridoxal-phosphate dependent TrpB-like enzyme 14 430 5.3E-188 T 28-03-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CU254_RS28260 a2028dbd17d7430b44a9e08dab1420c3 450 Gene3D G3DSA:3.40.50.1100 219 424 1.2E-29 T 28-03-2018 CU254_RS28260 a2028dbd17d7430b44a9e08dab1420c3 450 PIRSF PIRSF001413 10 434 9.2E-116 T 28-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CU254_RS28260 a2028dbd17d7430b44a9e08dab1420c3 450 Gene3D G3DSA:3.40.50.1100 90 218 3.0E-24 T 28-03-2018 CU254_RS28115 29e32fb1fe30f257604a5aee27890065 399 SUPERFAMILY SSF53383 61 396 1.45E-31 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS28115 29e32fb1fe30f257604a5aee27890065 399 Gene3D G3DSA:3.40.640.10 24 291 7.3E-19 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS28115 29e32fb1fe30f257604a5aee27890065 399 Gene3D G3DSA:3.90.1150.10 292 399 7.8E-5 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS37940 cf44b4d564122c47ee4e027440f676d8 428 Gene3D G3DSA:3.90.170.10 266 428 3.1E-69 T 28-03-2018 CU254_RS37940 cf44b4d564122c47ee4e027440f676d8 428 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 428 200.611 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CU254_RS37940 cf44b4d564122c47ee4e027440f676d8 428 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 28-03-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CU254_RS37940 cf44b4d564122c47ee4e027440f676d8 428 SUPERFAMILY SSF52540 1 426 1.27E-168 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS37940 cf44b4d564122c47ee4e027440f676d8 428 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 132 143 - T 28-03-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CU254_RS37940 cf44b4d564122c47ee4e027440f676d8 428 Pfam PF00709 Adenylosuccinate synthetase 4 422 2.7E-175 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CU254_RS37940 cf44b4d564122c47ee4e027440f676d8 428 Gene3D G3DSA:3.40.440.10 151 265 2.6E-25 T 28-03-2018 CU254_RS37940 cf44b4d564122c47ee4e027440f676d8 428 Gene3D G3DSA:3.40.440.10 1 150 5.4E-51 T 28-03-2018 CU254_RS37940 cf44b4d564122c47ee4e027440f676d8 428 SMART SM00788 3 423 5.9E-275 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CU254_RS37940 cf44b4d564122c47ee4e027440f676d8 428 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 425 8.1E-164 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CU254_RS33625 26a1c6c1a7f951bf5dfb5aa4a646f2de 351 Gene3D G3DSA:3.20.20.30 2 346 1.7E-73 T 28-03-2018 CU254_RS33625 26a1c6c1a7f951bf5dfb5aa4a646f2de 351 Pfam PF00296 Luciferase-like monooxygenase 16 316 1.4E-68 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS33625 26a1c6c1a7f951bf5dfb5aa4a646f2de 351 SUPERFAMILY SSF51679 5 341 7.46E-77 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS04615 b291248db3da4080ed5a8952220043a0 177 SUPERFAMILY SSF69255 7 77 8.63E-7 T 28-03-2018 CU254_RS04615 b291248db3da4080ed5a8952220043a0 177 Gene3D G3DSA:2.40.50.260 2 88 4.1E-9 T 28-03-2018 CU254_RS24945 aa5d98b15a89812fcd24db3cb5d6a1b5 157 Gene3D G3DSA:3.30.300.20 4 120 3.7E-27 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CU254_RS24945 aa5d98b15a89812fcd24db3cb5d6a1b5 157 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 1 115 5.0E-21 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CU254_RS24945 aa5d98b15a89812fcd24db3cb5d6a1b5 157 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 2 120 18.67 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CU254_RS24945 aa5d98b15a89812fcd24db3cb5d6a1b5 157 ProSitePatterns PS01319 Ribosome-binding factor A signature. 79 100 - T 28-03-2018 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 CU254_RS24945 aa5d98b15a89812fcd24db3cb5d6a1b5 157 SUPERFAMILY SSF89919 1 116 7.33E-27 T 28-03-2018 IPR023799 Ribosome-binding factor A domain CU254_RS24945 aa5d98b15a89812fcd24db3cb5d6a1b5 157 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 9 100 8.0E-25 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CU254_RS24945 aa5d98b15a89812fcd24db3cb5d6a1b5 157 Pfam PF02033 Ribosome-binding factor A 6 113 3.8E-25 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CU254_RS31075 1cf3ae8079faf59b510902c483d45f66 174 Gene3D G3DSA:3.40.630.30 2 174 1.0E-24 T 28-03-2018 CU254_RS31075 1cf3ae8079faf59b510902c483d45f66 174 Pfam PF13302 Acetyltransferase (GNAT) domain 12 157 7.4E-27 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS31075 1cf3ae8079faf59b510902c483d45f66 174 SUPERFAMILY SSF55729 6 158 1.73E-31 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS26845 3ed6d2baaa05851ed1f92b4ed66da1ae 1054 SUPERFAMILY SSF50249 491 574 3.29E-16 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CU254_RS26845 3ed6d2baaa05851ed1f92b4ed66da1ae 1054 Pfam PF10150 Ribonuclease E/G family 570 843 1.2E-103 T 28-03-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 CU254_RS26845 3ed6d2baaa05851ed1f92b4ed66da1ae 1054 Gene3D G3DSA:2.40.50.140 486 573 2.3E-26 T 28-03-2018 CU254_RS26845 3ed6d2baaa05851ed1f92b4ed66da1ae 1054 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 29 73 5.0E-8 T 28-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal CU254_RS26845 3ed6d2baaa05851ed1f92b4ed66da1ae 1054 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 466 870 2.2E-151 T 28-03-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 CU254_RS26845 3ed6d2baaa05851ed1f92b4ed66da1ae 1054 SMART SM00316 489 568 5.3E-7 T 28-03-2018 IPR022967 RNA-binding domain, S1 CU254_RS26845 3ed6d2baaa05851ed1f92b4ed66da1ae 1054 Gene3D G3DSA:3.30.56.50 30 72 2.9E-8 T 28-03-2018 CU254_RS12235 1f49e210f414734209f8f387fc9be8fe 541 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 192 320 1.4E-29 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CU254_RS12235 1f49e210f414734209f8f387fc9be8fe 541 Gene3D G3DSA:3.40.50.970 1 187 1.0E-39 T 28-03-2018 CU254_RS12235 1f49e210f414734209f8f387fc9be8fe 541 Gene3D G3DSA:3.40.50.1220 188 341 4.8E-38 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CU254_RS12235 1f49e210f414734209f8f387fc9be8fe 541 Gene3D G3DSA:3.40.50.970 342 528 1.6E-28 T 28-03-2018 CU254_RS12235 1f49e210f414734209f8f387fc9be8fe 541 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 411 430 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CU254_RS12235 1f49e210f414734209f8f387fc9be8fe 541 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 6 171 1.4E-43 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CU254_RS12235 1f49e210f414734209f8f387fc9be8fe 541 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 381 520 3.2E-25 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CU254_RS12235 1f49e210f414734209f8f387fc9be8fe 541 SUPERFAMILY SSF52518 6 187 2.21E-39 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS12235 1f49e210f414734209f8f387fc9be8fe 541 SUPERFAMILY SSF52518 354 528 4.65E-40 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS12235 1f49e210f414734209f8f387fc9be8fe 541 SUPERFAMILY SSF52467 157 348 1.12E-38 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CU254_RS25420 4781dd1ea9af7ea17e8ca04e60ca3f15 506 Gene3D G3DSA:3.40.50.300 1 234 4.3E-51 T 28-03-2018 CU254_RS25420 4781dd1ea9af7ea17e8ca04e60ca3f15 506 Gene3D G3DSA:3.40.50.300 260 504 1.2E-33 T 28-03-2018 CU254_RS25420 4781dd1ea9af7ea17e8ca04e60ca3f15 506 Pfam PF00005 ABC transporter 278 433 1.5E-16 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS25420 4781dd1ea9af7ea17e8ca04e60ca3f15 506 Pfam PF00005 ABC transporter 20 171 1.0E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS25420 4781dd1ea9af7ea17e8ca04e60ca3f15 506 SUPERFAMILY SSF52540 4 231 7.48E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS25420 4781dd1ea9af7ea17e8ca04e60ca3f15 506 ProSitePatterns PS00211 ABC transporters family signature. 406 420 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS25420 4781dd1ea9af7ea17e8ca04e60ca3f15 506 SUPERFAMILY SSF52540 246 486 1.31E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS25420 4781dd1ea9af7ea17e8ca04e60ca3f15 506 SMART SM00382 29 219 1.9E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS25420 4781dd1ea9af7ea17e8ca04e60ca3f15 506 SMART SM00382 286 481 1.4E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS41550 13fe485aa3bac539de693b7b9d13c6b4 325 Pfam PF04796 Plasmid encoded RepA protein 84 247 9.0E-28 T 28-03-2018 IPR006881 Plasmid encoded RepA protein CU254_RS06230 78c6bb4675142d99cf23bbef3c91aa08 430 Gene3D G3DSA:1.20.1250.20 212 428 3.8E-28 T 28-03-2018 CU254_RS06230 78c6bb4675142d99cf23bbef3c91aa08 430 Pfam PF07690 Major Facilitator Superfamily 20 312 6.3E-25 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS06230 78c6bb4675142d99cf23bbef3c91aa08 430 SUPERFAMILY SSF103473 7 421 1.7E-68 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS06230 78c6bb4675142d99cf23bbef3c91aa08 430 Gene3D G3DSA:1.20.1250.20 8 211 1.6E-26 T 28-03-2018 CU254_RS00950 0e3142dab800f984e6c2352b4d74995c 130 SUPERFAMILY SSF55298 13 128 5.05E-22 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CU254_RS00950 0e3142dab800f984e6c2352b4d74995c 130 Gene3D G3DSA:3.30.1330.40 4 130 2.2E-20 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CU254_RS00950 0e3142dab800f984e6c2352b4d74995c 130 Pfam PF01042 Endoribonuclease L-PSP 26 128 1.7E-17 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family CU254_RS35075 c67d7ef47eaa5658fe1c45e938444fa1 207 PIRSF PIRSF000349 1 202 8.4E-69 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CU254_RS35075 c67d7ef47eaa5658fe1c45e938444fa1 207 PRINTS PR01703 Manganese superoxide dismutase signature 28 41 6.4E-19 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CU254_RS35075 c67d7ef47eaa5658fe1c45e938444fa1 207 PRINTS PR01703 Manganese superoxide dismutase signature 7 18 6.4E-19 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CU254_RS35075 c67d7ef47eaa5658fe1c45e938444fa1 207 PRINTS PR01703 Manganese superoxide dismutase signature 158 170 6.4E-19 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CU254_RS35075 c67d7ef47eaa5658fe1c45e938444fa1 207 PRINTS PR01703 Manganese superoxide dismutase signature 120 128 6.4E-19 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CU254_RS35075 c67d7ef47eaa5658fe1c45e938444fa1 207 PRINTS PR01703 Manganese superoxide dismutase signature 67 80 6.4E-19 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CU254_RS35075 c67d7ef47eaa5658fe1c45e938444fa1 207 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 160 167 - T 28-03-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CU254_RS35075 c67d7ef47eaa5658fe1c45e938444fa1 207 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 84 9.8E-29 T 28-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CU254_RS35075 c67d7ef47eaa5658fe1c45e938444fa1 207 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 91 193 3.4E-33 T 28-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CU254_RS35075 c67d7ef47eaa5658fe1c45e938444fa1 207 SUPERFAMILY SSF46609 3 88 8.51E-29 T 28-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CU254_RS35075 c67d7ef47eaa5658fe1c45e938444fa1 207 Gene3D G3DSA:1.10.287.990 21 84 3.4E-17 T 28-03-2018 CU254_RS35075 c67d7ef47eaa5658fe1c45e938444fa1 207 SUPERFAMILY SSF54719 84 197 5.24E-41 T 28-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CU254_RS05625 3ed2bb07643db2ba5257fe8313952a86 410 Pfam PF10518 TAT (twin-arginine translocation) pathway signal sequence 3 25 6.8E-8 T 28-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal CU254_RS05625 3ed2bb07643db2ba5257fe8313952a86 410 Pfam PF04261 Dyp-type peroxidase family 55 398 3.0E-95 T 28-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 CU254_RS05625 3ed2bb07643db2ba5257fe8313952a86 410 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 55 398 2.4E-88 T 28-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 CU254_RS05625 3ed2bb07643db2ba5257fe8313952a86 410 TIGRFAM TIGR01412 tat_substr_1: Tat-translocated enzyme 2 409 6.3E-129 T 28-03-2018 IPR006313 Deferrochelatase/peroxidase EfeB GO:0004601|GO:0015684|GO:0020037|GO:0033212 CU254_RS05625 3ed2bb07643db2ba5257fe8313952a86 410 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 4 33 6.7E-5 T 28-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal CU254_RS05625 3ed2bb07643db2ba5257fe8313952a86 410 SUPERFAMILY SSF54909 50 398 5.01E-86 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS27830 9b82c68c5c296e0ca4237b9cdee42ce7 339 Pfam PF13088 BNR repeat-like domain 10 312 4.7E-35 T 28-03-2018 IPR011040 Sialidases KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 CU254_RS27830 9b82c68c5c296e0ca4237b9cdee42ce7 339 SUPERFAMILY SSF50939 1 339 7.01E-76 T 28-03-2018 IPR011040 Sialidases KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 CU254_RS27830 9b82c68c5c296e0ca4237b9cdee42ce7 339 Gene3D G3DSA:2.120.10.10 1 339 9.4E-67 T 28-03-2018 CU254_RS17420 e12ff71e15c7685f92cd13e88860b955 181 Gene3D G3DSA:1.20.1290.10 4 167 2.5E-25 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CU254_RS17420 e12ff71e15c7685f92cd13e88860b955 181 SUPERFAMILY SSF69118 11 161 5.76E-33 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CU254_RS17420 e12ff71e15c7685f92cd13e88860b955 181 TIGRFAM TIGR01926 peroxid_rel: uncharacterized peroxidase-related enzyme 11 150 6.1E-27 T 28-03-2018 IPR010195 Uncharacterised peroxidase-related CU254_RS17420 e12ff71e15c7685f92cd13e88860b955 181 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 40 73 2.5E-8 T 28-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CU254_RS17420 e12ff71e15c7685f92cd13e88860b955 181 Pfam PF02627 Carboxymuconolactone decarboxylase family 21 79 6.4E-8 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CU254_RS17170 d3461ebed5b75048988cc1ccdf9badcd 609 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 85 596 1.7E-81 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CU254_RS17170 d3461ebed5b75048988cc1ccdf9badcd 609 PRINTS PR01806 Virulence factor MviN signature 446 465 1.7E-23 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CU254_RS17170 d3461ebed5b75048988cc1ccdf9badcd 609 PRINTS PR01806 Virulence factor MviN signature 348 374 1.7E-23 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CU254_RS17170 d3461ebed5b75048988cc1ccdf9badcd 609 PRINTS PR01806 Virulence factor MviN signature 116 135 1.7E-23 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CU254_RS17170 d3461ebed5b75048988cc1ccdf9badcd 609 PRINTS PR01806 Virulence factor MviN signature 135 151 1.7E-23 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CU254_RS17170 d3461ebed5b75048988cc1ccdf9badcd 609 PRINTS PR01806 Virulence factor MviN signature 212 236 1.7E-23 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CU254_RS17170 d3461ebed5b75048988cc1ccdf9badcd 609 PRINTS PR01806 Virulence factor MviN signature 236 257 1.7E-23 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CU254_RS17170 d3461ebed5b75048988cc1ccdf9badcd 609 Pfam PF03023 MviN-like protein 114 542 1.4E-90 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CU254_RS08955 6105ca8f6e251586f35dc1be63eea0df 135 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 57 132 5.0E-5 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CU254_RS08955 6105ca8f6e251586f35dc1be63eea0df 135 SUPERFAMILY SSF55961 5 133 2.1E-14 T 28-03-2018 CU254_RS08955 6105ca8f6e251586f35dc1be63eea0df 135 Gene3D G3DSA:3.30.530.20 2 135 1.0E-8 T 28-03-2018 IPR023393 START-like domain CU254_RS10385 3eb9d184e3182d84e50372106755da94 355 Gene3D G3DSA:1.10.540.10 8 95 5.8E-20 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS10385 3eb9d184e3182d84e50372106755da94 355 SUPERFAMILY SSF47203 224 352 2.74E-21 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS10385 3eb9d184e3182d84e50372106755da94 355 Gene3D G3DSA:1.20.140.10 208 334 5.2E-21 T 28-03-2018 CU254_RS10385 3eb9d184e3182d84e50372106755da94 355 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 11 104 2.3E-14 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS10385 3eb9d184e3182d84e50372106755da94 355 SUPERFAMILY SSF56645 11 202 5.76E-31 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS10385 3eb9d184e3182d84e50372106755da94 355 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 228 331 2.1E-14 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS10385 3eb9d184e3182d84e50372106755da94 355 Gene3D G3DSA:2.40.110.10 96 207 4.6E-6 T 28-03-2018 CU254_RS31065 578af878ee559c0c2d709c32fc337c71 276 SUPERFAMILY SSF56112 22 260 5.1E-27 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS31065 578af878ee559c0c2d709c32fc337c71 276 Gene3D G3DSA:3.90.1200.10 102 272 6.4E-19 T 28-03-2018 CU254_RS31065 578af878ee559c0c2d709c32fc337c71 276 Pfam PF01636 Phosphotransferase enzyme family 42 229 4.6E-14 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CU254_RS02695 69a04f00e11139bcacbff756b17cb769 193 Gene3D G3DSA:1.10.340.30 14 141 1.0E-9 T 28-03-2018 CU254_RS02695 69a04f00e11139bcacbff756b17cb769 193 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 27 185 1.5E-11 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CU254_RS02695 69a04f00e11139bcacbff756b17cb769 193 TIGRFAM TIGR03252 TIGR03252: uncharacterized HhH-GPD family protein 4 193 2.6E-90 T 28-03-2018 IPR017658 Conserved hypothetical protein CHP03252, HhH-GPD CU254_RS02695 69a04f00e11139bcacbff756b17cb769 193 SUPERFAMILY SSF48150 7 147 1.17E-12 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CU254_RS36700 74a867f5f714473c28d5e0841d4488cc 239 SUPERFAMILY SSF46894 173 237 6.8E-17 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS36700 74a867f5f714473c28d5e0841d4488cc 239 SMART SM00421 177 234 4.8E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS36700 74a867f5f714473c28d5e0841d4488cc 239 Gene3D G3DSA:1.10.10.10 48 238 8.9E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS36700 74a867f5f714473c28d5e0841d4488cc 239 Pfam PF00196 Bacterial regulatory proteins, luxR family 179 233 3.3E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS36700 74a867f5f714473c28d5e0841d4488cc 239 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 194 8.4E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS36700 74a867f5f714473c28d5e0841d4488cc 239 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 194 210 8.4E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS36700 74a867f5f714473c28d5e0841d4488cc 239 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 210 222 8.4E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS21970 05dd0e9b0f539abfcc3df1328b85675b 449 Gene3D G3DSA:3.90.1200.10 229 425 4.8E-14 T 28-03-2018 CU254_RS21970 05dd0e9b0f539abfcc3df1328b85675b 449 SUPERFAMILY SSF56112 123 414 3.4E-19 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS26660 4e94655a514d7a099f8f862c631ddb25 340 Pfam PF12697 Alpha/beta hydrolase family 66 310 1.4E-21 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS26660 4e94655a514d7a099f8f862c631ddb25 340 Gene3D G3DSA:3.40.50.1820 21 317 2.9E-37 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS26660 4e94655a514d7a099f8f862c631ddb25 340 SUPERFAMILY SSF53474 57 315 1.68E-41 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS26660 4e94655a514d7a099f8f862c631ddb25 340 PRINTS PR00111 Alpha/beta hydrolase fold signature 135 148 8.3E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS26660 4e94655a514d7a099f8f862c631ddb25 340 PRINTS PR00111 Alpha/beta hydrolase fold signature 90 105 8.3E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS26660 4e94655a514d7a099f8f862c631ddb25 340 PRINTS PR00412 Epoxide hydrolase signature 293 315 7.7E-6 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS26660 4e94655a514d7a099f8f862c631ddb25 340 PRINTS PR00412 Epoxide hydrolase signature 90 105 7.7E-6 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS26660 4e94655a514d7a099f8f862c631ddb25 340 PRINTS PR00412 Epoxide hydrolase signature 70 88 7.7E-6 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS34835 aed184157b3eb196c3d50c209fac4b03 120 SUPERFAMILY SSF46785 6 117 6.93E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS34835 aed184157b3eb196c3d50c209fac4b03 120 Pfam PF01638 HxlR-like helix-turn-helix 17 107 3.7E-24 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type CU254_RS34835 aed184157b3eb196c3d50c209fac4b03 120 Gene3D G3DSA:1.10.10.10 1 120 2.9E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS05730 f3bda4b94f50eeb0a2508a8f2e28948c 345 PIRSF PIRSF039102 1 345 2.1E-103 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CU254_RS05730 f3bda4b94f50eeb0a2508a8f2e28948c 345 Pfam PF01820 D-ala D-ala ligase N-terminus 5 121 4.9E-27 T 28-03-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CU254_RS05730 f3bda4b94f50eeb0a2508a8f2e28948c 345 SUPERFAMILY SSF56059 131 336 4.28E-51 T 28-03-2018 CU254_RS05730 f3bda4b94f50eeb0a2508a8f2e28948c 345 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 282 310 - T 28-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CU254_RS05730 f3bda4b94f50eeb0a2508a8f2e28948c 345 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 4 340 35.684 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CU254_RS05730 f3bda4b94f50eeb0a2508a8f2e28948c 345 Pfam PF07478 D-ala D-ala ligase C-terminus 161 336 7.2E-59 T 28-03-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CU254_RS05730 f3bda4b94f50eeb0a2508a8f2e28948c 345 Gene3D G3DSA:3.40.50.20 1 141 3.2E-39 T 28-03-2018 CU254_RS05730 f3bda4b94f50eeb0a2508a8f2e28948c 345 Gene3D G3DSA:3.30.470.20 198 345 1.2E-35 T 28-03-2018 CU254_RS05730 f3bda4b94f50eeb0a2508a8f2e28948c 345 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 5 339 4.1E-85 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CU254_RS05730 f3bda4b94f50eeb0a2508a8f2e28948c 345 SUPERFAMILY SSF52440 3 130 1.82E-34 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CU254_RS05730 f3bda4b94f50eeb0a2508a8f2e28948c 345 Gene3D G3DSA:3.30.1490.20 151 197 6.7E-17 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CU254_RS05730 f3bda4b94f50eeb0a2508a8f2e28948c 345 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 98 109 - T 28-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CU254_RS18330 912596bf9b737fece7f96f20f4a3f0d5 314 SMART SM00475 3 283 3.6E-87 T 28-03-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 CU254_RS18330 912596bf9b737fece7f96f20f4a3f0d5 314 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 194 274 8.7E-19 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CU254_RS18330 912596bf9b737fece7f96f20f4a3f0d5 314 Gene3D G3DSA:3.40.50.1010 4 202 4.2E-56 T 28-03-2018 IPR029060 PIN domain-like CU254_RS18330 912596bf9b737fece7f96f20f4a3f0d5 314 SUPERFAMILY SSF47807 194 306 2.39E-20 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CU254_RS18330 912596bf9b737fece7f96f20f4a3f0d5 314 SUPERFAMILY SSF88723 4 156 2.06E-39 T 28-03-2018 IPR029060 PIN domain-like CU254_RS18330 912596bf9b737fece7f96f20f4a3f0d5 314 Gene3D G3DSA:1.10.150.20 203 281 7.2E-19 T 28-03-2018 CU254_RS18330 912596bf9b737fece7f96f20f4a3f0d5 314 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 5 184 1.5E-48 T 28-03-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 CU254_RS18330 912596bf9b737fece7f96f20f4a3f0d5 314 SMART SM00279 191 226 3.0E-12 T 28-03-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 CU254_RS28460 b969e07eb526ce12c609acca5025d868 201 PIRSF PIRSF006135 27 201 1.1E-48 T 28-03-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CU254_RS28460 b969e07eb526ce12c609acca5025d868 201 SUPERFAMILY SSF52540 29 200 9.11E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS28460 b969e07eb526ce12c609acca5025d868 201 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 29 200 3.0E-52 T 28-03-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CU254_RS28460 b969e07eb526ce12c609acca5025d868 201 Gene3D G3DSA:3.40.50.300 29 200 5.5E-52 T 28-03-2018 CU254_RS31775 2297a594cb32211871ba9549b1a7560c 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 248 4.5E-62 T 28-03-2018 CU254_RS31775 2297a594cb32211871ba9549b1a7560c 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 1.2E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS31775 2297a594cb32211871ba9549b1a7560c 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 1.2E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS31775 2297a594cb32211871ba9549b1a7560c 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 1.2E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS31775 2297a594cb32211871ba9549b1a7560c 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.2E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS31775 2297a594cb32211871ba9549b1a7560c 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.2E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS31775 2297a594cb32211871ba9549b1a7560c 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.2E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS31775 2297a594cb32211871ba9549b1a7560c 250 Gene3D G3DSA:3.40.50.720 43 250 1.0E-55 T 28-03-2018 CU254_RS31775 2297a594cb32211871ba9549b1a7560c 250 Gene3D G3DSA:3.40.50.720 1 42 1.6E-10 T 28-03-2018 CU254_RS31775 2297a594cb32211871ba9549b1a7560c 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 2.4E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS31775 2297a594cb32211871ba9549b1a7560c 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 2.4E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS31775 2297a594cb32211871ba9549b1a7560c 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 2.4E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS31775 2297a594cb32211871ba9549b1a7560c 250 SUPERFAMILY SSF51735 1 249 1.13E-74 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS31775 2297a594cb32211871ba9549b1a7560c 250 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS22210 a72465f119220eccd01ad5a4be265fa3 576 SUPERFAMILY SSF51905 289 377 3.71E-54 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS22210 a72465f119220eccd01ad5a4be265fa3 576 SUPERFAMILY SSF51905 5 190 3.71E-54 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS22210 a72465f119220eccd01ad5a4be265fa3 576 Gene3D G3DSA:3.50.50.60 1 432 2.3E-62 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS22210 a72465f119220eccd01ad5a4be265fa3 576 Pfam PF01494 FAD binding domain 5 368 2.1E-121 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CU254_RS22210 a72465f119220eccd01ad5a4be265fa3 576 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 353 369 1.8E-47 T 28-03-2018 CU254_RS22210 a72465f119220eccd01ad5a4be265fa3 576 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 169 184 1.8E-47 T 28-03-2018 CU254_RS22210 a72465f119220eccd01ad5a4be265fa3 576 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 302 317 1.8E-47 T 28-03-2018 CU254_RS22210 a72465f119220eccd01ad5a4be265fa3 576 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 317 333 1.8E-47 T 28-03-2018 CU254_RS22210 a72465f119220eccd01ad5a4be265fa3 576 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 335 353 1.8E-47 T 28-03-2018 CU254_RS22210 a72465f119220eccd01ad5a4be265fa3 576 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 1.8E-47 T 28-03-2018 CU254_RS36740 ac63215bc8c0897c764ec7333cd68b92 394 Gene3D G3DSA:2.40.10.10 185 280 1.9E-19 T 28-03-2018 CU254_RS36740 ac63215bc8c0897c764ec7333cd68b92 394 SUPERFAMILY SSF50494 189 375 3.91E-34 T 28-03-2018 IPR009003 Peptidase S1, PA clan CU254_RS36740 ac63215bc8c0897c764ec7333cd68b92 394 Pfam PF13365 Trypsin-like peptidase domain 217 353 4.9E-21 T 28-03-2018 CU254_RS36740 ac63215bc8c0897c764ec7333cd68b92 394 PRINTS PR00834 HtrA/DegQ protease family signature 324 341 4.9E-9 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CU254_RS36740 ac63215bc8c0897c764ec7333cd68b92 394 PRINTS PR00834 HtrA/DegQ protease family signature 284 308 4.9E-9 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CU254_RS36740 ac63215bc8c0897c764ec7333cd68b92 394 PRINTS PR00834 HtrA/DegQ protease family signature 245 265 4.9E-9 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CU254_RS36740 ac63215bc8c0897c764ec7333cd68b92 394 PRINTS PR00834 HtrA/DegQ protease family signature 225 237 4.9E-9 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CU254_RS36740 ac63215bc8c0897c764ec7333cd68b92 394 Pfam PF02674 Colicin V production protein 4 144 1.9E-14 T 28-03-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 CU254_RS36740 ac63215bc8c0897c764ec7333cd68b92 394 Gene3D G3DSA:2.40.10.10 281 385 2.1E-15 T 28-03-2018 CU254_RS01990 158d76817491ebefd116861c22888ee4 81 Gene3D G3DSA:1.10.287.310 7 69 1.7E-23 T 28-03-2018 CU254_RS01990 158d76817491ebefd116861c22888ee4 81 Pfam PF00831 Ribosomal L29 protein 9 65 2.4E-24 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS01990 158d76817491ebefd116861c22888ee4 81 SUPERFAMILY SSF46561 7 68 3.01E-22 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS01990 158d76817491ebefd116861c22888ee4 81 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 6 65 16.458 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS01990 158d76817491ebefd116861c22888ee4 81 TIGRFAM TIGR00012 L29: ribosomal protein uL29 10 65 3.2E-19 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS28390 dfa8e748d2ab622c97b21b5a70faf680 208 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 1 196 7.5E-53 T 28-03-2018 IPR015796 Impact family, bacterial/archaeal CU254_RS28390 dfa8e748d2ab622c97b21b5a70faf680 208 SUPERFAMILY SSF54211 4 131 7.59E-37 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CU254_RS28390 dfa8e748d2ab622c97b21b5a70faf680 208 Pfam PF09186 Domain of unknown function (DUF1949) 140 194 3.4E-11 T 28-03-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal CU254_RS28390 dfa8e748d2ab622c97b21b5a70faf680 208 Pfam PF01205 Uncharacterized protein family UPF0029 19 124 5.7E-26 T 28-03-2018 IPR001498 Impact, N-terminal CU254_RS28390 dfa8e748d2ab622c97b21b5a70faf680 208 Gene3D G3DSA:3.30.230.30 5 133 5.1E-40 T 28-03-2018 IPR001498 Impact, N-terminal CU254_RS28390 dfa8e748d2ab622c97b21b5a70faf680 208 Gene3D G3DSA:3.30.70.240 135 198 6.1E-16 T 28-03-2018 CU254_RS28390 dfa8e748d2ab622c97b21b5a70faf680 208 SUPERFAMILY SSF54980 137 202 3.81E-8 T 28-03-2018 IPR035647 EF-G domain III/V-like CU254_RS02020 d2551ed86fd8feaf7ea703be956c5ff4 132 SUPERFAMILY SSF56047 3 132 8.24E-44 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS02020 d2551ed86fd8feaf7ea703be956c5ff4 132 Pfam PF00410 Ribosomal protein S8 5 132 2.4E-49 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS02020 d2551ed86fd8feaf7ea703be956c5ff4 132 Gene3D G3DSA:3.30.1490.10 76 131 4.5E-20 T 28-03-2018 CU254_RS02020 d2551ed86fd8feaf7ea703be956c5ff4 132 Gene3D G3DSA:3.30.1370.30 1 67 2.7E-25 T 28-03-2018 CU254_RS02020 d2551ed86fd8feaf7ea703be956c5ff4 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 31.205 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS08170 7ad959cfdcd2abdf1aff0c9d35fdecd9 169 SUPERFAMILY SSF55961 4 122 1.34E-5 T 28-03-2018 CU254_RS08170 7ad959cfdcd2abdf1aff0c9d35fdecd9 169 Gene3D G3DSA:3.30.530.20 3 168 6.1E-10 T 28-03-2018 IPR023393 START-like domain CU254_RS29615 dba3668cceaa48c669330d16a43c11ca 572 Gene3D G3DSA:3.40.50.300 338 570 4.6E-46 T 28-03-2018 CU254_RS29615 dba3668cceaa48c669330d16a43c11ca 572 SMART SM00382 366 544 5.7E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS29615 dba3668cceaa48c669330d16a43c11ca 572 Pfam PF02653 Branched-chain amino acid transport system / permease component 42 294 4.3E-22 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CU254_RS29615 dba3668cceaa48c669330d16a43c11ca 572 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 545 567 8.2E-6 T 28-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CU254_RS29615 dba3668cceaa48c669330d16a43c11ca 572 SUPERFAMILY SSF52540 331 562 4.87E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS29615 dba3668cceaa48c669330d16a43c11ca 572 Pfam PF00005 ABC transporter 357 495 5.0E-20 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS29615 dba3668cceaa48c669330d16a43c11ca 572 Gene3D G3DSA:1.10.3470.10 39 303 4.3E-19 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CU254_RS36205 d5d733d6120ea2a46ec5cf4343302df4 201 Pfam PF01470 Pyroglutamyl peptidase 2 173 8.2E-60 T 28-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like CU254_RS36205 d5d733d6120ea2a46ec5cf4343302df4 201 PIRSF PIRSF015592 1 199 1.6E-65 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CU254_RS36205 d5d733d6120ea2a46ec5cf4343302df4 201 SUPERFAMILY SSF53182 2 194 1.07E-57 T 28-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like CU254_RS36205 d5d733d6120ea2a46ec5cf4343302df4 201 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 58 70 2.2E-38 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CU254_RS36205 d5d733d6120ea2a46ec5cf4343302df4 201 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 3 26 2.2E-38 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CU254_RS36205 d5d733d6120ea2a46ec5cf4343302df4 201 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 128 144 2.2E-38 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CU254_RS36205 d5d733d6120ea2a46ec5cf4343302df4 201 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 158 170 2.2E-38 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CU254_RS36205 d5d733d6120ea2a46ec5cf4343302df4 201 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 76 96 2.2E-38 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CU254_RS36205 d5d733d6120ea2a46ec5cf4343302df4 201 ProSitePatterns PS01334 Pyrrolidone-carboxylate peptidase cysteine active site. 126 140 - T 28-03-2018 IPR033694 Pyroglutamyl peptidase I, Cys active site CU254_RS36205 d5d733d6120ea2a46ec5cf4343302df4 201 TIGRFAM TIGR00504 pyro_pdase: pyroglutamyl-peptidase I 3 200 2.5E-64 T 28-03-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 CU254_RS36205 d5d733d6120ea2a46ec5cf4343302df4 201 ProSitePatterns PS01333 Pyrrolidone-carboxylate peptidase glutamic acid active site. 65 81 - T 28-03-2018 IPR033693 Pyroglutamyl peptidase I, Glu active site CU254_RS36205 d5d733d6120ea2a46ec5cf4343302df4 201 Gene3D G3DSA:3.40.630.20 1 198 3.3E-53 T 28-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like CU254_RS33180 4664bd09c17377ae0424aed8e9f0281c 432 Gene3D G3DSA:3.40.190.10 198 388 1.9E-19 T 28-03-2018 CU254_RS33180 4664bd09c17377ae0424aed8e9f0281c 432 Gene3D G3DSA:3.40.190.10 28 197 7.4E-22 T 28-03-2018 CU254_RS33180 4664bd09c17377ae0424aed8e9f0281c 432 Pfam PF13416 Bacterial extracellular solute-binding protein 56 361 1.1E-30 T 28-03-2018 CU254_RS33180 4664bd09c17377ae0424aed8e9f0281c 432 SUPERFAMILY SSF53850 39 429 2.43E-43 T 28-03-2018 CU254_RS11240 2c60d12c5c4a35856f365cbac4297e4c 116 Gene3D G3DSA:2.40.30.10 12 100 3.9E-16 T 28-03-2018 CU254_RS11240 2c60d12c5c4a35856f365cbac4297e4c 116 SUPERFAMILY SSF50447 12 92 1.26E-13 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CU254_RS24730 3373c279b1f891bcef163bd5a778dbc0 150 Gene3D G3DSA:1.10.260.40 6 77 7.9E-15 T 28-03-2018 CU254_RS24730 3373c279b1f891bcef163bd5a778dbc0 150 Pfam PF13560 Helix-turn-helix domain 9 70 7.8E-11 T 28-03-2018 CU254_RS24730 3373c279b1f891bcef163bd5a778dbc0 150 SUPERFAMILY SSF47413 4 70 4.65E-13 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS24730 3373c279b1f891bcef163bd5a778dbc0 150 SMART SM00530 13 68 9.1E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS22015 1f6db0b08865fa4701ccc19c78356e62 284 Pfam PF00296 Luciferase-like monooxygenase 18 234 1.1E-49 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS22015 1f6db0b08865fa4701ccc19c78356e62 284 Gene3D G3DSA:3.20.20.30 16 240 4.5E-60 T 28-03-2018 CU254_RS22015 1f6db0b08865fa4701ccc19c78356e62 284 SUPERFAMILY SSF51679 18 276 8.51E-56 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS22015 1f6db0b08865fa4701ccc19c78356e62 284 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 18 258 7.3E-75 T 28-03-2018 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted CU254_RS39730 3b7541846e490c261208fc5c33757f4c 466 SUPERFAMILY SSF47413 44 96 1.48E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS39730 3b7541846e490c261208fc5c33757f4c 466 Gene3D G3DSA:3.30.1190.10 62 125 1.4E-6 T 28-03-2018 CU254_RS39730 3b7541846e490c261208fc5c33757f4c 466 SUPERFAMILY SSF48452 219 337 5.42E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS39730 3b7541846e490c261208fc5c33757f4c 466 SMART SM00530 43 98 8.3E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS39730 3b7541846e490c261208fc5c33757f4c 466 Pfam PF13424 Tetratricopeptide repeat 228 287 3.0E-7 T 28-03-2018 CU254_RS39730 3b7541846e490c261208fc5c33757f4c 466 Gene3D G3DSA:1.10.10.60 29 61 2.8E-5 T 28-03-2018 CU254_RS39730 3b7541846e490c261208fc5c33757f4c 466 Pfam PF13560 Helix-turn-helix domain 48 95 4.0E-7 T 28-03-2018 CU254_RS39730 3b7541846e490c261208fc5c33757f4c 466 Gene3D G3DSA:1.25.40.10 150 461 3.7E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS29490 8f41c4a98e6c8e2e800e4158ec6222a8 344 SMART SM00861 14 189 2.6E-62 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CU254_RS29490 8f41c4a98e6c8e2e800e4158ec6222a8 344 Pfam PF02779 Transketolase, pyrimidine binding domain 13 185 3.7E-48 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CU254_RS29490 8f41c4a98e6c8e2e800e4158ec6222a8 344 Pfam PF02780 Transketolase, C-terminal domain 212 334 7.5E-34 T 28-03-2018 IPR033248 Transketolase, C-terminal domain CU254_RS29490 8f41c4a98e6c8e2e800e4158ec6222a8 344 Gene3D G3DSA:3.40.50.920 213 343 1.6E-34 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CU254_RS29490 8f41c4a98e6c8e2e800e4158ec6222a8 344 SUPERFAMILY SSF52518 12 222 1.18E-68 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS29490 8f41c4a98e6c8e2e800e4158ec6222a8 344 SUPERFAMILY SSF52922 207 342 4.45E-39 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CU254_RS29490 8f41c4a98e6c8e2e800e4158ec6222a8 344 Gene3D G3DSA:3.40.50.970 10 212 2.2E-66 T 28-03-2018 CU254_RS20450 3c3d59b2deffb8201bd8a1ec2ee03115 236 SMART SM00849 27 202 5.2E-33 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS20450 3c3d59b2deffb8201bd8a1ec2ee03115 236 Gene3D G3DSA:3.60.15.10 20 231 8.9E-40 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS20450 3c3d59b2deffb8201bd8a1ec2ee03115 236 Pfam PF00753 Metallo-beta-lactamase superfamily 28 202 4.0E-13 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS20450 3c3d59b2deffb8201bd8a1ec2ee03115 236 SUPERFAMILY SSF56281 26 216 6.77E-46 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS02930 39759f15e93ece754001101a34ab128d 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 59 1.2E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS02930 39759f15e93ece754001101a34ab128d 194 SUPERFAMILY SSF46689 4 75 1.85E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS02930 39759f15e93ece754001101a34ab128d 194 Gene3D G3DSA:1.10.357.10 56 194 6.9E-11 T 28-03-2018 CU254_RS02930 39759f15e93ece754001101a34ab128d 194 Gene3D G3DSA:1.10.10.60 2 55 1.3E-11 T 28-03-2018 CU254_RS22985 639900ae17f7136b610209b873f48350 205 Gene3D G3DSA:2.60.40.1240 64 202 1.6E-6 T 28-03-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain CU254_RS02470 a76e2a58081e5c5f31ec6c0a3d55ed90 215 Gene3D G3DSA:1.20.1540.10 24 197 3.4E-22 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CU254_RS02470 a76e2a58081e5c5f31ec6c0a3d55ed90 215 SUPERFAMILY SSF144091 25 191 1.05E-19 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CU254_RS02470 a76e2a58081e5c5f31ec6c0a3d55ed90 215 Pfam PF01694 Rhomboid family 62 174 2.1E-11 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CU254_RS14805 7981d05e3d2e36845e2d05b23ad54587 291 SUPERFAMILY SSF46785 47 86 7.55E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS14805 7981d05e3d2e36845e2d05b23ad54587 291 Pfam PF13730 Helix-turn-helix domain 27 77 1.5E-8 T 28-03-2018 CU254_RS14805 7981d05e3d2e36845e2d05b23ad54587 291 Gene3D G3DSA:1.10.10.10 15 94 4.1E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS29635 cbdedbe07ca6e23a4a8636ab3c06e9e6 229 Gene3D G3DSA:1.10.10.60 3 59 1.4E-17 T 28-03-2018 CU254_RS29635 cbdedbe07ca6e23a4a8636ab3c06e9e6 229 SUPERFAMILY SSF48498 82 147 8.45E-8 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS29635 cbdedbe07ca6e23a4a8636ab3c06e9e6 229 Gene3D G3DSA:1.10.357.10 60 184 2.3E-17 T 28-03-2018 CU254_RS29635 cbdedbe07ca6e23a4a8636ab3c06e9e6 229 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 59 1.8E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS29635 cbdedbe07ca6e23a4a8636ab3c06e9e6 229 SUPERFAMILY SSF46689 7 72 3.4E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS03985 511e972efe569e585eeebac2c4576822 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 8.0E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS03985 511e972efe569e585eeebac2c4576822 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 8.0E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS03985 511e972efe569e585eeebac2c4576822 207 Gene3D G3DSA:1.10.357.10 66 201 4.8E-21 T 28-03-2018 CU254_RS03985 511e972efe569e585eeebac2c4576822 207 SUPERFAMILY SSF48498 88 199 1.17E-24 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS03985 511e972efe569e585eeebac2c4576822 207 SUPERFAMILY SSF46689 9 92 7.48E-22 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS03985 511e972efe569e585eeebac2c4576822 207 Gene3D G3DSA:1.10.10.60 2 65 4.7E-22 T 28-03-2018 CU254_RS03985 511e972efe569e585eeebac2c4576822 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 68 2.0E-18 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS00065 9ff80ca8985fba7a7d693ef5d6c93c7e 268 Pfam PF02517 CAAX protease self-immunity 102 187 3.2E-14 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CU254_RS15665 c60029aaf7876e40d99472f21b633294 552 Gene3D G3DSA:1.20.5.170 237 326 0.0036 T 28-03-2018 CU254_RS15665 c60029aaf7876e40d99472f21b633294 552 Gene3D G3DSA:1.10.287.1060 11 99 5.2E-4 T 28-03-2018 CU254_RS15665 c60029aaf7876e40d99472f21b633294 552 Pfam PF06259 Alpha/beta hydrolase 315 465 2.7E-25 T 28-03-2018 IPR010427 Protein of unknown function DUF1023 CU254_RS15665 c60029aaf7876e40d99472f21b633294 552 Gene3D G3DSA:3.40.50.1820 338 543 3.9E-4 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS15665 c60029aaf7876e40d99472f21b633294 552 SUPERFAMILY SSF53474 412 456 2.19E-5 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS15665 c60029aaf7876e40d99472f21b633294 552 SUPERFAMILY SSF53474 500 536 2.19E-5 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS24760 2bb842c2b7b554b3cd3a62d212d48120 173 Gene3D G3DSA:3.40.630.30 9 152 1.9E-18 T 28-03-2018 CU254_RS24760 2bb842c2b7b554b3cd3a62d212d48120 173 Pfam PF00583 Acetyltransferase (GNAT) family 45 117 1.6E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS24760 2bb842c2b7b554b3cd3a62d212d48120 173 SUPERFAMILY SSF55729 7 130 1.06E-20 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS37710 ef836c1f5712c66a5493ff0a76febd71 387 Pfam PF01070 FMN-dependent dehydrogenase 34 384 1.5E-111 T 28-03-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 CU254_RS37710 ef836c1f5712c66a5493ff0a76febd71 387 PIRSF PIRSF000138 8 387 1.1E-115 T 28-03-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 CU254_RS37710 ef836c1f5712c66a5493ff0a76febd71 387 SUPERFAMILY SSF51395 25 383 5.76E-88 T 28-03-2018 CU254_RS37710 ef836c1f5712c66a5493ff0a76febd71 387 Gene3D G3DSA:3.20.20.70 24 386 1.2E-97 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS37710 ef836c1f5712c66a5493ff0a76febd71 387 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 282 288 - T 28-03-2018 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 CU254_RS24710 ff8f2e45cb6782906e1031bd6d6da562 341 Gene3D G3DSA:3.20.20.70 2 341 4.6E-84 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS24710 ff8f2e45cb6782906e1031bd6d6da562 341 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 16 340 3.9E-112 T 28-03-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CU254_RS24710 ff8f2e45cb6782906e1031bd6d6da562 341 PIRSF PIRSF000164 15 341 1.3E-97 T 28-03-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 CU254_RS24710 ff8f2e45cb6782906e1031bd6d6da562 341 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 294 314 - T 28-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 CU254_RS24710 ff8f2e45cb6782906e1031bd6d6da562 341 SUPERFAMILY SSF51395 11 339 8.99E-92 T 28-03-2018 CU254_RS24710 ff8f2e45cb6782906e1031bd6d6da562 341 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 3 338 45.976 T 28-03-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CU254_RS24710 ff8f2e45cb6782906e1031bd6d6da562 341 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 83 102 - T 28-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 CU254_RS24710 ff8f2e45cb6782906e1031bd6d6da562 341 Pfam PF01180 Dihydroorotate dehydrogenase 51 340 2.2E-86 T 28-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 CU254_RS33755 24f5396dae3b28548dbb6bdbba03c7ff 498 Gene3D G3DSA:3.90.550.10 2 261 2.5E-60 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS33755 24f5396dae3b28548dbb6bdbba03c7ff 498 SUPERFAMILY SSF51161 260 448 3.26E-39 T 28-03-2018 IPR011004 Trimeric LpxA-like CU254_RS33755 24f5396dae3b28548dbb6bdbba03c7ff 498 Pfam PF12804 MobA-like NTP transferase domain 8 143 5.7E-23 T 28-03-2018 IPR025877 MobA-like NTP transferase CU254_RS33755 24f5396dae3b28548dbb6bdbba03c7ff 498 Gene3D G3DSA:2.160.10.10 262 448 4.4E-42 T 28-03-2018 CU254_RS33755 24f5396dae3b28548dbb6bdbba03c7ff 498 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 404 437 0.0019 T 28-03-2018 IPR001451 Hexapeptide repeat CU254_RS33755 24f5396dae3b28548dbb6bdbba03c7ff 498 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 278 309 2.5E-4 T 28-03-2018 IPR001451 Hexapeptide repeat CU254_RS33755 24f5396dae3b28548dbb6bdbba03c7ff 498 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 4 461 39.625 T 28-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 CU254_RS33755 24f5396dae3b28548dbb6bdbba03c7ff 498 SUPERFAMILY SSF53448 8 316 1.26E-60 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS33755 24f5396dae3b28548dbb6bdbba03c7ff 498 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 6 462 5.1E-169 T 28-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 CU254_RS05535 2599f6d737da701749b12c092f1872a4 179 SUPERFAMILY SSF46785 14 172 1.68E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS05535 2599f6d737da701749b12c092f1872a4 179 Gene3D G3DSA:1.10.10.10 1 149 2.4E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS05535 2599f6d737da701749b12c092f1872a4 179 Pfam PF03551 Transcriptional regulator PadR-like family 14 64 3.7E-6 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CU254_RS39495 1d2156edae11dbcf6f7773bc8cb6dcc8 413 SMART SM00220 12 270 4.5E-53 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CU254_RS39495 1d2156edae11dbcf6f7773bc8cb6dcc8 413 Gene3D G3DSA:3.30.200.20 7 100 1.2E-17 T 28-03-2018 CU254_RS39495 1d2156edae11dbcf6f7773bc8cb6dcc8 413 PIRSF PIRSF000654 12 260 2.3E-19 T 28-03-2018 CU254_RS39495 1d2156edae11dbcf6f7773bc8cb6dcc8 413 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 135 147 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CU254_RS39495 1d2156edae11dbcf6f7773bc8cb6dcc8 413 SUPERFAMILY SSF56112 9 280 8.5E-71 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS39495 1d2156edae11dbcf6f7773bc8cb6dcc8 413 Pfam PF00069 Protein kinase domain 13 259 7.7E-43 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CU254_RS39495 1d2156edae11dbcf6f7773bc8cb6dcc8 413 Gene3D G3DSA:1.10.510.10 101 264 2.5E-46 T 28-03-2018 CU254_RS26355 f2ad22e718effb5eda33821b81c3d413 462 SUPERFAMILY SSF52954 355 459 2.27E-34 T 28-03-2018 IPR004154 Anticodon-binding CU254_RS26355 f2ad22e718effb5eda33821b81c3d413 462 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 158 287 1.7E-9 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CU254_RS26355 f2ad22e718effb5eda33821b81c3d413 462 Hamap MF_00253_B Glycine--tRNA ligase [glyQS]. 3 460 49.825 T 28-03-2018 IPR022961 Glycine-tRNA ligase, bacterial GO:0004820 KEGG: 00970+6.1.1.14 CU254_RS26355 f2ad22e718effb5eda33821b81c3d413 462 Gene3D G3DSA:3.30.930.10 3 224 6.1E-53 T 28-03-2018 CU254_RS26355 f2ad22e718effb5eda33821b81c3d413 462 Gene3D G3DSA:3.30.930.10 225 355 2.2E-40 T 28-03-2018 CU254_RS26355 f2ad22e718effb5eda33821b81c3d413 462 Gene3D G3DSA:3.40.50.800 356 460 7.5E-27 T 28-03-2018 IPR004154 Anticodon-binding CU254_RS26355 f2ad22e718effb5eda33821b81c3d413 462 SUPERFAMILY SSF55681 5 371 1.4E-122 T 28-03-2018 CU254_RS26355 f2ad22e718effb5eda33821b81c3d413 462 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 6 231 4.7E-84 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CU254_RS26355 f2ad22e718effb5eda33821b81c3d413 462 PRINTS PR01043 Glycyl-tRNA synthetase signature 25 39 3.9E-54 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CU254_RS26355 f2ad22e718effb5eda33821b81c3d413 462 PRINTS PR01043 Glycyl-tRNA synthetase signature 159 176 3.9E-54 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CU254_RS26355 f2ad22e718effb5eda33821b81c3d413 462 PRINTS PR01043 Glycyl-tRNA synthetase signature 191 208 3.9E-54 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CU254_RS26355 f2ad22e718effb5eda33821b81c3d413 462 PRINTS PR01043 Glycyl-tRNA synthetase signature 405 424 3.9E-54 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CU254_RS26355 f2ad22e718effb5eda33821b81c3d413 462 PRINTS PR01043 Glycyl-tRNA synthetase signature 138 150 3.9E-54 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CU254_RS26355 f2ad22e718effb5eda33821b81c3d413 462 PRINTS PR01043 Glycyl-tRNA synthetase signature 319 331 3.9E-54 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CU254_RS26355 f2ad22e718effb5eda33821b81c3d413 462 PRINTS PR01043 Glycyl-tRNA synthetase signature 208 218 3.9E-54 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CU254_RS26355 f2ad22e718effb5eda33821b81c3d413 462 Pfam PF03129 Anticodon binding domain 368 455 1.0E-23 T 28-03-2018 IPR004154 Anticodon-binding CU254_RS23465 2b2e857b40af00f1de1b2a29fb5f058b 246 SUPERFAMILY SSF51735 10 246 6.71E-76 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS23465 2b2e857b40af00f1de1b2a29fb5f058b 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 245 3.8E-62 T 28-03-2018 CU254_RS23465 2b2e857b40af00f1de1b2a29fb5f058b 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 2.1E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23465 2b2e857b40af00f1de1b2a29fb5f058b 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 2.1E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23465 2b2e857b40af00f1de1b2a29fb5f058b 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 2.1E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23465 2b2e857b40af00f1de1b2a29fb5f058b 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 2.1E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23465 2b2e857b40af00f1de1b2a29fb5f058b 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 2.1E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23465 2b2e857b40af00f1de1b2a29fb5f058b 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 2.1E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23465 2b2e857b40af00f1de1b2a29fb5f058b 246 Gene3D G3DSA:3.40.50.720 3 51 4.9E-8 T 28-03-2018 CU254_RS23465 2b2e857b40af00f1de1b2a29fb5f058b 246 Gene3D G3DSA:3.40.50.720 52 246 2.8E-60 T 28-03-2018 CU254_RS23465 2b2e857b40af00f1de1b2a29fb5f058b 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.7E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23465 2b2e857b40af00f1de1b2a29fb5f058b 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.7E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23465 2b2e857b40af00f1de1b2a29fb5f058b 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 1.7E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS29275 20d9eab82b59cebe9c9e6cf95d181d6e 224 Gene3D G3DSA:3.50.30.40 4 175 2.6E-46 T 28-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CU254_RS29275 20d9eab82b59cebe9c9e6cf95d181d6e 224 Pfam PF03737 Aldolase/RraA 18 173 1.7E-33 T 28-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CU254_RS29275 20d9eab82b59cebe9c9e6cf95d181d6e 224 SUPERFAMILY SSF89562 14 184 6.15E-35 T 28-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CU254_RS00175 54f94ee752df73ec5b00eb75b63dec14 237 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 189 201 3.0E-6 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CU254_RS00175 54f94ee752df73ec5b00eb75b63dec14 237 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 59 74 3.0E-6 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CU254_RS00175 54f94ee752df73ec5b00eb75b63dec14 237 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 106 120 3.0E-6 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CU254_RS00175 54f94ee752df73ec5b00eb75b63dec14 237 Pfam PF00089 Trypsin 42 231 1.2E-29 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CU254_RS00175 54f94ee752df73ec5b00eb75b63dec14 237 SMART SM00020 34 231 2.2E-19 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CU254_RS00175 54f94ee752df73ec5b00eb75b63dec14 237 Gene3D G3DSA:2.40.10.10 65 118 3.8E-13 T 28-03-2018 CU254_RS00175 54f94ee752df73ec5b00eb75b63dec14 237 Gene3D G3DSA:2.40.10.10 35 64 2.5E-10 T 28-03-2018 CU254_RS00175 54f94ee752df73ec5b00eb75b63dec14 237 SUPERFAMILY SSF50494 8 236 3.63E-36 T 28-03-2018 IPR009003 Peptidase S1, PA clan CU254_RS00175 54f94ee752df73ec5b00eb75b63dec14 237 Gene3D G3DSA:2.40.10.10 119 236 2.4E-16 T 28-03-2018 CU254_RS03490 536285dd3bfb1da2211b1b93b61ba5ab 330 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 2 321 1.2E-132 T 28-03-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 CU254_RS03490 536285dd3bfb1da2211b1b93b61ba5ab 330 Gene3D G3DSA:3.40.50.720 1 186 4.4E-42 T 28-03-2018 CU254_RS03490 536285dd3bfb1da2211b1b93b61ba5ab 330 SUPERFAMILY SSF51735 1 322 2.54E-98 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS03490 536285dd3bfb1da2211b1b93b61ba5ab 330 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 307 2.9E-79 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS03490 536285dd3bfb1da2211b1b93b61ba5ab 330 Gene3D G3DSA:3.90.25.10 187 329 1.1E-49 T 28-03-2018 CU254_RS23835 0b57e967c6a5df25c4c8e694b51f2e05 314 Pfam PF13560 Helix-turn-helix domain 5 84 4.4E-14 T 28-03-2018 CU254_RS23835 0b57e967c6a5df25c4c8e694b51f2e05 314 SUPERFAMILY SSF47413 29 80 8.8E-7 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS23835 0b57e967c6a5df25c4c8e694b51f2e05 314 SMART SM00530 9 81 2.4E-4 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS23835 0b57e967c6a5df25c4c8e694b51f2e05 314 Gene3D G3DSA:1.10.260.40 1 81 1.4E-13 T 28-03-2018 CU254_RS36430 463d4798089586b74bd0c28b0ecedfb3 155 SUPERFAMILY SSF55961 3 140 3.3E-20 T 28-03-2018 CU254_RS36430 463d4798089586b74bd0c28b0ecedfb3 155 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 12 135 4.3E-13 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CU254_RS36430 463d4798089586b74bd0c28b0ecedfb3 155 Gene3D G3DSA:3.30.530.20 1 141 1.1E-24 T 28-03-2018 IPR023393 START-like domain CU254_RS06130 d635436f91344a592fa8f5acb0dd24eb 224 Pfam PF00106 short chain dehydrogenase 3 185 5.4E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS06130 d635436f91344a592fa8f5acb0dd24eb 224 SUPERFAMILY SSF51735 2 213 1.61E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS06130 d635436f91344a592fa8f5acb0dd24eb 224 Gene3D G3DSA:3.40.50.720 2 219 6.1E-48 T 28-03-2018 CU254_RS06130 d635436f91344a592fa8f5acb0dd24eb 224 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 118 134 4.4E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS06130 d635436f91344a592fa8f5acb0dd24eb 224 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 69 80 4.4E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS06130 d635436f91344a592fa8f5acb0dd24eb 224 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 4.4E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS06130 d635436f91344a592fa8f5acb0dd24eb 224 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 180 4.4E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS06130 d635436f91344a592fa8f5acb0dd24eb 224 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 163 4.4E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS06130 d635436f91344a592fa8f5acb0dd24eb 224 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 124 132 3.6E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS06130 d635436f91344a592fa8f5acb0dd24eb 224 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 69 80 3.6E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS06130 d635436f91344a592fa8f5acb0dd24eb 224 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 163 3.6E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS06130 d635436f91344a592fa8f5acb0dd24eb 224 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 131 159 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS03740 8d384bd8d756dca934ad0724b92811bf 262 PRINTS PR00599 Methionine aminopeptidase-1 signature 95 111 8.3E-17 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CU254_RS03740 8d384bd8d756dca934ad0724b92811bf 262 PRINTS PR00599 Methionine aminopeptidase-1 signature 196 208 8.3E-17 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CU254_RS03740 8d384bd8d756dca934ad0724b92811bf 262 PRINTS PR00599 Methionine aminopeptidase-1 signature 165 177 8.3E-17 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CU254_RS03740 8d384bd8d756dca934ad0724b92811bf 262 PRINTS PR00599 Methionine aminopeptidase-1 signature 73 86 8.3E-17 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CU254_RS03740 8d384bd8d756dca934ad0724b92811bf 262 Hamap MF_01974 Methionine aminopeptidase [map]. 2 254 32.33 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CU254_RS03740 8d384bd8d756dca934ad0724b92811bf 262 Pfam PF00557 Metallopeptidase family M24 13 245 8.4E-45 T 28-03-2018 IPR000994 Peptidase M24 CU254_RS03740 8d384bd8d756dca934ad0724b92811bf 262 SUPERFAMILY SSF55920 2 253 2.75E-69 T 28-03-2018 IPR000994 Peptidase M24 CU254_RS03740 8d384bd8d756dca934ad0724b92811bf 262 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 2 253 2.4E-72 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CU254_RS03740 8d384bd8d756dca934ad0724b92811bf 262 Gene3D G3DSA:3.90.230.10 1 261 7.7E-65 T 28-03-2018 CU254_RS16445 1779a8725c1325e8f7d496162cf47819 330 SUPERFAMILY SSF161098 108 310 1.57E-29 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS16445 1779a8725c1325e8f7d496162cf47819 330 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 130 327 1.2E-29 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS16445 1779a8725c1325e8f7d496162cf47819 330 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 22 55 2.6E-8 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CU254_RS16445 1779a8725c1325e8f7d496162cf47819 330 Gene3D G3DSA:1.10.3720.10 23 317 1.2E-48 T 28-03-2018 CU254_RS31125 1cd50c8edbfbade7b835d4b1f69e0a98 207 SUPERFAMILY SSF101473 4 205 1.44E-51 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CU254_RS31125 1cd50c8edbfbade7b835d4b1f69e0a98 207 SMART SM01120 32 204 1.2E-67 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CU254_RS31125 1cd50c8edbfbade7b835d4b1f69e0a98 207 TIGRFAM TIGR02365 dha_L_ycgS: dihydroxyacetone kinase, L subunit 10 203 1.5E-66 T 28-03-2018 IPR012737 Dihydroxyacetone kinase, subunit L GO:0016772 CU254_RS31125 1cd50c8edbfbade7b835d4b1f69e0a98 207 Pfam PF02734 DAK2 domain 32 203 2.2E-51 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CU254_RS03540 52df1deec188a195223e3ad2f4f9d524 211 Gene3D G3DSA:1.10.10.60 4 39 1.8E-9 T 28-03-2018 CU254_RS03540 52df1deec188a195223e3ad2f4f9d524 211 Gene3D G3DSA:1.10.357.10 71 211 8.3E-36 T 28-03-2018 CU254_RS03540 52df1deec188a195223e3ad2f4f9d524 211 SUPERFAMILY SSF48498 85 209 2.67E-27 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS03540 52df1deec188a195223e3ad2f4f9d524 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 64 3.9E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS03540 52df1deec188a195223e3ad2f4f9d524 211 SUPERFAMILY SSF46689 6 81 1.59E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS03540 52df1deec188a195223e3ad2f4f9d524 211 Gene3D G3DSA:1.10.260.40 40 70 1.4E-7 T 28-03-2018 CU254_RS27090 bcd3087dd85e53bde7bb2ffe5c15e5fd 208 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 7 186 1.6E-31 T 28-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CU254_RS27090 bcd3087dd85e53bde7bb2ffe5c15e5fd 208 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 8 90 2.1E-13 T 28-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CU254_RS27090 bcd3087dd85e53bde7bb2ffe5c15e5fd 208 SUPERFAMILY SSF109854 2 125 3.2E-19 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CU254_RS27090 bcd3087dd85e53bde7bb2ffe5c15e5fd 208 Gene3D G3DSA:1.20.120.450 1 207 9.9E-18 T 28-03-2018 CU254_RS29075 08938b9b49e4165a17c920f10026fafc 321 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 319 1.2E-35 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS29075 08938b9b49e4165a17c920f10026fafc 321 SUPERFAMILY SSF161098 91 305 2.78E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS29075 08938b9b49e4165a17c920f10026fafc 321 Gene3D G3DSA:1.10.3720.10 84 317 9.0E-33 T 28-03-2018 CU254_RS17820 70a47e327060123204c70b2ce35a7ab0 105 Pfam PF00355 Rieske [2Fe-2S] domain 3 85 2.0E-17 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CU254_RS17820 70a47e327060123204c70b2ce35a7ab0 105 Gene3D G3DSA:2.102.10.10 1 105 4.7E-24 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CU254_RS17820 70a47e327060123204c70b2ce35a7ab0 105 SUPERFAMILY SSF50022 3 100 1.7E-29 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CU254_RS21330 4e5378cac6c5cd1e9be775e4783bb99b 353 Pfam PF00817 impB/mucB/samB family 20 163 9.3E-39 T 28-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CU254_RS21330 4e5378cac6c5cd1e9be775e4783bb99b 353 Pfam PF14520 Helix-hairpin-helix domain 193 228 4.3E-7 T 28-03-2018 CU254_RS21330 4e5378cac6c5cd1e9be775e4783bb99b 353 Hamap MF_01113 DNA polymerase IV [dinB]. 14 352 28.929 T 28-03-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 CU254_RS21330 4e5378cac6c5cd1e9be775e4783bb99b 353 SUPERFAMILY SSF56672 16 246 2.58E-68 T 28-03-2018 CU254_RS21330 4e5378cac6c5cd1e9be775e4783bb99b 353 Gene3D G3DSA:1.10.150.20 181 255 4.7E-17 T 28-03-2018 CU254_RS21330 4e5378cac6c5cd1e9be775e4783bb99b 353 SUPERFAMILY SSF100879 253 349 1.08E-21 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CU254_RS21330 4e5378cac6c5cd1e9be775e4783bb99b 353 Gene3D G3DSA:3.30.1490.100 256 350 1.4E-21 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CU254_RS21330 4e5378cac6c5cd1e9be775e4783bb99b 353 Gene3D G3DSA:3.30.70.270 128 180 5.1E-15 T 28-03-2018 CU254_RS21330 4e5378cac6c5cd1e9be775e4783bb99b 353 Gene3D G3DSA:3.30.70.270 56 127 5.6E-18 T 28-03-2018 CU254_RS21330 4e5378cac6c5cd1e9be775e4783bb99b 353 Pfam PF11799 impB/mucB/samB family C-terminal domain 251 348 5.6E-13 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CU254_RS24075 9af8f15b9703bf11c9dd74fc5a2f8037 254 SUPERFAMILY SSF46458 106 218 1.21E-23 T 28-03-2018 IPR009050 Globin-like CU254_RS24075 9af8f15b9703bf11c9dd74fc5a2f8037 254 Gene3D G3DSA:1.10.490.10 103 226 1.3E-26 T 28-03-2018 CU254_RS24075 9af8f15b9703bf11c9dd74fc5a2f8037 254 Pfam PF03992 Antibiotic biosynthesis monooxygenase 4 76 1.4E-8 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain CU254_RS24075 9af8f15b9703bf11c9dd74fc5a2f8037 254 SUPERFAMILY SSF54909 2 92 3.69E-14 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS24075 9af8f15b9703bf11c9dd74fc5a2f8037 254 Pfam PF01152 Bacterial-like globin 106 202 6.4E-15 T 28-03-2018 IPR001486 Truncated hemoglobin GO:0019825 CU254_RS24075 9af8f15b9703bf11c9dd74fc5a2f8037 254 Gene3D G3DSA:3.30.70.100 1 102 1.4E-18 T 28-03-2018 CU254_RS28000 ff5ca5195ce16b9619cf019273455f65 292 Gene3D G3DSA:3.40.190.10 180 273 1.7E-19 T 28-03-2018 CU254_RS28000 ff5ca5195ce16b9619cf019273455f65 292 Gene3D G3DSA:1.10.10.10 1 83 4.3E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS28000 ff5ca5195ce16b9619cf019273455f65 292 Pfam PF03466 LysR substrate binding domain 88 290 5.1E-32 T 28-03-2018 IPR005119 LysR, substrate-binding CU254_RS28000 ff5ca5195ce16b9619cf019273455f65 292 Gene3D G3DSA:3.40.190.10 92 179 3.1E-18 T 28-03-2018 CU254_RS28000 ff5ca5195ce16b9619cf019273455f65 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.3E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS28000 ff5ca5195ce16b9619cf019273455f65 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.3E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS28000 ff5ca5195ce16b9619cf019273455f65 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.3E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS28000 ff5ca5195ce16b9619cf019273455f65 292 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 2.1E-23 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS28000 ff5ca5195ce16b9619cf019273455f65 292 SUPERFAMILY SSF53850 89 291 4.34E-30 T 28-03-2018 CU254_RS28000 ff5ca5195ce16b9619cf019273455f65 292 SUPERFAMILY SSF46785 3 88 1.58E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS20885 ff0778d640a255e3670ed928f0fe8f4d 649 Gene3D G3DSA:3.90.1580.10 475 620 2.1E-17 T 28-03-2018 CU254_RS20885 ff0778d640a255e3670ed928f0fe8f4d 649 Pfam PF03781 Sulfatase-modifying factor enzyme 1 487 572 2.6E-17 T 28-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 CU254_RS20885 ff0778d640a255e3670ed928f0fe8f4d 649 Gene3D G3DSA:3.20.20.70 28 403 3.4E-5 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS20885 ff0778d640a255e3670ed928f0fe8f4d 649 SUPERFAMILY SSF56436 492 647 1.88E-23 T 28-03-2018 IPR016187 C-type lectin fold CU254_RS40015 56710409f7aaec9b61cf6e6a5f2f661c 154 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 14 96 1.3E-15 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CU254_RS40015 56710409f7aaec9b61cf6e6a5f2f661c 154 Gene3D G3DSA:2.30.110.10 5 141 1.0E-26 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS40015 56710409f7aaec9b61cf6e6a5f2f661c 154 SUPERFAMILY SSF50475 13 149 6.66E-31 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS40015 56710409f7aaec9b61cf6e6a5f2f661c 154 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 17 141 3.9E-39 T 28-03-2018 IPR019920 F420-binding domain, putative CU254_RS15315 f5e35c22585f445c5a386bba4704f9ae 306 SUPERFAMILY SSF56645 2 108 2.54E-5 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS15315 f5e35c22585f445c5a386bba4704f9ae 306 Gene3D G3DSA:1.20.140.10 162 285 4.9E-24 T 28-03-2018 CU254_RS15315 f5e35c22585f445c5a386bba4704f9ae 306 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 165 289 2.8E-17 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS15315 f5e35c22585f445c5a386bba4704f9ae 306 SUPERFAMILY SSF47203 164 290 6.28E-26 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS15315 f5e35c22585f445c5a386bba4704f9ae 306 Gene3D G3DSA:1.10.540.10 1 108 4.4E-8 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS37605 91791ea8794a372f3e2b7e32a2f40bf0 79 Pfam PF04149 Domain of unknown function (DUF397) 17 70 2.7E-19 T 28-03-2018 IPR007278 Domain of unknown function DUF397 CU254_RS35240 29bf61639a169c1d27d24fb1d54eab32 305 Pfam PF00994 Probable molybdopterin binding domain 7 147 1.3E-25 T 28-03-2018 IPR001453 MoaB/Mog domain CU254_RS35240 29bf61639a169c1d27d24fb1d54eab32 305 SUPERFAMILY SSF54690 172 303 4.97E-38 T 28-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CU254_RS35240 29bf61639a169c1d27d24fb1d54eab32 305 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 64 77 - T 28-03-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 CU254_RS35240 29bf61639a169c1d27d24fb1d54eab32 305 Gene3D G3DSA:3.90.1170.40 167 305 3.9E-45 T 28-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CU254_RS35240 29bf61639a169c1d27d24fb1d54eab32 305 SMART SM00852 6 148 5.8E-16 T 28-03-2018 IPR001453 MoaB/Mog domain CU254_RS35240 29bf61639a169c1d27d24fb1d54eab32 305 Pfam PF02391 MoaE protein 173 285 3.7E-34 T 28-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CU254_RS35240 29bf61639a169c1d27d24fb1d54eab32 305 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 5 141 4.2E-27 T 28-03-2018 IPR001453 MoaB/Mog domain CU254_RS35240 29bf61639a169c1d27d24fb1d54eab32 305 Gene3D G3DSA:3.40.980.10 2 159 1.7E-34 T 28-03-2018 IPR001453 MoaB/Mog domain CU254_RS35240 29bf61639a169c1d27d24fb1d54eab32 305 SUPERFAMILY SSF53218 3 152 2.88E-37 T 28-03-2018 IPR001453 MoaB/Mog domain CU254_RS39440 b7312b9cc2ace91ef4e5881a003c65b1 236 Pfam PF00005 ABC transporter 20 157 7.0E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS39440 b7312b9cc2ace91ef4e5881a003c65b1 236 SMART SM00382 28 205 1.6E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS39440 b7312b9cc2ace91ef4e5881a003c65b1 236 SUPERFAMILY SSF52540 2 224 2.03E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS39440 b7312b9cc2ace91ef4e5881a003c65b1 236 Gene3D G3DSA:3.40.50.300 1 236 1.2E-66 T 28-03-2018 CU254_RS25810 c685e7921303cdf798aca433f2f58b33 337 Gene3D G3DSA:3.30.530.20 116 286 1.8E-17 T 28-03-2018 IPR023393 START-like domain CU254_RS25810 c685e7921303cdf798aca433f2f58b33 337 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 125 240 1.5E-11 T 28-03-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 CU254_RS25810 c685e7921303cdf798aca433f2f58b33 337 SUPERFAMILY SSF55961 119 244 3.21E-17 T 28-03-2018 CU254_RS34790 d5ecf16c9f69b22d1ec770421d0fce42 301 Gene3D G3DSA:3.40.50.300 1 273 2.7E-65 T 28-03-2018 CU254_RS34790 d5ecf16c9f69b22d1ec770421d0fce42 301 SUPERFAMILY SSF52540 3 221 4.08E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS34790 d5ecf16c9f69b22d1ec770421d0fce42 301 SMART SM00382 27 206 5.3E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS34790 d5ecf16c9f69b22d1ec770421d0fce42 301 Pfam PF00005 ABC transporter 18 158 2.9E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS34790 d5ecf16c9f69b22d1ec770421d0fce42 301 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS34790 d5ecf16c9f69b22d1ec770421d0fce42 301 Pfam PF13732 Domain of unknown function (DUF4162) 212 293 2.7E-7 T 28-03-2018 IPR025302 Domain of unknown function DUF4162 CU254_RS20010 6fd800ec9729c5783cc88367d968751a 284 Pfam PF04672 S-adenosyl methyltransferase 16 283 3.2E-74 T 28-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CU254_RS20010 6fd800ec9729c5783cc88367d968751a 284 SUPERFAMILY SSF53335 21 249 5.92E-35 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS20010 6fd800ec9729c5783cc88367d968751a 284 Gene3D G3DSA:3.40.50.150 2 283 2.0E-44 T 28-03-2018 CU254_RS20010 6fd800ec9729c5783cc88367d968751a 284 PIRSF PIRSF017393 1 284 2.9E-78 T 28-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CU254_RS34885 c0672fd4b7cd386d82874b0b672a1363 241 SUPERFAMILY SSF51735 6 238 5.79E-56 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS34885 c0672fd4b7cd386d82874b0b672a1363 241 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 236 1.3E-42 T 28-03-2018 CU254_RS34885 c0672fd4b7cd386d82874b0b672a1363 241 Gene3D G3DSA:3.40.50.720 2 239 2.3E-50 T 28-03-2018 CU254_RS34885 c0672fd4b7cd386d82874b0b672a1363 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 136 2.0E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS34885 c0672fd4b7cd386d82874b0b672a1363 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 2.0E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS34885 c0672fd4b7cd386d82874b0b672a1363 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 2.0E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS34885 c0672fd4b7cd386d82874b0b672a1363 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 182 2.0E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS34885 c0672fd4b7cd386d82874b0b672a1363 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 2.0E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS34885 c0672fd4b7cd386d82874b0b672a1363 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 202 222 2.0E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS19405 3598f5c15583f625047dced616ae642d 259 Gene3D G3DSA:3.40.50.1110 1 192 1.5E-35 T 28-03-2018 CU254_RS19405 3598f5c15583f625047dced616ae642d 259 SUPERFAMILY SSF52266 4 190 1.68E-39 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CU254_RS19405 3598f5c15583f625047dced616ae642d 259 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 7 179 1.6E-27 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CU254_RS14585 c0648cc4b5c7c12dafda205f058c3f15 254 SUPERFAMILY SSF46785 16 96 4.74E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS14585 c0648cc4b5c7c12dafda205f058c3f15 254 Pfam PF00392 Bacterial regulatory proteins, gntR family 23 86 2.4E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS14585 c0648cc4b5c7c12dafda205f058c3f15 254 SMART SM00866 106 244 1.3E-31 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CU254_RS14585 c0648cc4b5c7c12dafda205f058c3f15 254 SMART SM00345 27 86 2.3E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS14585 c0648cc4b5c7c12dafda205f058c3f15 254 Gene3D G3DSA:3.40.1410.10 86 247 9.0E-40 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CU254_RS14585 c0648cc4b5c7c12dafda205f058c3f15 254 Gene3D G3DSA:1.10.10.10 13 85 4.8E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS14585 c0648cc4b5c7c12dafda205f058c3f15 254 SUPERFAMILY SSF64288 74 248 1.19E-43 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CU254_RS14585 c0648cc4b5c7c12dafda205f058c3f15 254 Pfam PF07702 UTRA domain 108 243 1.0E-36 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CU254_RS14585 c0648cc4b5c7c12dafda205f058c3f15 254 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 60 7.8E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS14585 c0648cc4b5c7c12dafda205f058c3f15 254 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 60 76 7.8E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS04530 57c6a294584433989ed1760d33557f3b 150 SUPERFAMILY SSF47741 83 145 1.7E-27 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CU254_RS04530 57c6a294584433989ed1760d33557f3b 150 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 39 47 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CU254_RS04530 57c6a294584433989ed1760d33557f3b 150 SUPERFAMILY SSF54292 2 87 8.65E-27 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CU254_RS04530 57c6a294584433989ed1760d33557f3b 150 Gene3D G3DSA:3.10.20.30 1 73 1.5E-25 T 28-03-2018 IPR012675 Beta-grasp domain CU254_RS04530 57c6a294584433989ed1760d33557f3b 150 Gene3D G3DSA:1.10.150.120 74 150 2.5E-31 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CU254_RS04530 57c6a294584433989ed1760d33557f3b 150 Pfam PF01799 [2Fe-2S] binding domain 72 140 1.8E-27 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CU254_RS04530 57c6a294584433989ed1760d33557f3b 150 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 6 62 5.0E-9 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CU254_RS16345 379d13b31dd66dda46c247448f85849e 425 Gene3D G3DSA:3.40.190.10 29 164 9.2E-4 T 28-03-2018 CU254_RS16345 379d13b31dd66dda46c247448f85849e 425 SUPERFAMILY SSF53850 38 417 5.83E-68 T 28-03-2018 CU254_RS16345 379d13b31dd66dda46c247448f85849e 425 Pfam PF01547 Bacterial extracellular solute-binding protein 53 333 2.4E-38 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 CU254_RS16345 379d13b31dd66dda46c247448f85849e 425 Gene3D G3DSA:3.40.190.10 165 421 8.0E-38 T 28-03-2018 CU254_RS24905 f0f598c35a5451af247778c8234098c2 305 SUPERFAMILY SSF88697 248 304 9.94E-12 T 28-03-2018 IPR015947 PUA-like domain CU254_RS24905 f0f598c35a5451af247778c8234098c2 305 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 35 191 5.2E-48 T 28-03-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 CU254_RS24905 f0f598c35a5451af247778c8234098c2 305 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 13 302 16.918 T 28-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 CU254_RS24905 f0f598c35a5451af247778c8234098c2 305 Pfam PF09142 tRNA Pseudouridine synthase II, C terminal 248 302 4.4E-18 T 28-03-2018 IPR015225 tRNA pseudouridine synthase II, TruB, subfamily 2, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 CU254_RS24905 f0f598c35a5451af247778c8234098c2 305 Gene3D G3DSA:3.30.2350.10 13 238 2.3E-76 T 28-03-2018 CU254_RS24905 f0f598c35a5451af247778c8234098c2 305 Gene3D G3DSA:2.30.130.10 240 302 4.0E-17 T 28-03-2018 IPR002478 PUA domain GO:0003723 CU254_RS24905 f0f598c35a5451af247778c8234098c2 305 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 15 230 6.9E-64 T 28-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 CU254_RS24905 f0f598c35a5451af247778c8234098c2 305 SUPERFAMILY SSF55120 14 235 1.28E-67 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CU254_RS24905 f0f598c35a5451af247778c8234098c2 305 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 192 233 3.0E-12 T 28-03-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 CU254_RS41425 e6e68c7d9a6dcae2f853226155783257 788 Gene3D G3DSA:3.40.50.300 9 175 1.2E-13 T 28-03-2018 CU254_RS41425 e6e68c7d9a6dcae2f853226155783257 788 PRINTS PR00364 Disease resistance protein signature 234 248 3.1E-8 T 28-03-2018 CU254_RS41425 e6e68c7d9a6dcae2f853226155783257 788 PRINTS PR00364 Disease resistance protein signature 39 54 3.1E-8 T 28-03-2018 CU254_RS41425 e6e68c7d9a6dcae2f853226155783257 788 PRINTS PR00364 Disease resistance protein signature 127 141 3.1E-8 T 28-03-2018 CU254_RS41425 e6e68c7d9a6dcae2f853226155783257 788 Gene3D G3DSA:1.10.10.10 316 788 9.3E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS41425 e6e68c7d9a6dcae2f853226155783257 788 Pfam PF00196 Bacterial regulatory proteins, luxR family 723 769 1.4E-6 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS41425 e6e68c7d9a6dcae2f853226155783257 788 SUPERFAMILY SSF46894 713 783 1.8E-10 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS41425 e6e68c7d9a6dcae2f853226155783257 788 Pfam PF13191 AAA ATPase domain 18 165 6.3E-9 T 28-03-2018 CU254_RS41425 e6e68c7d9a6dcae2f853226155783257 788 SMART SM00421 720 778 4.8E-5 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS41425 e6e68c7d9a6dcae2f853226155783257 788 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 723 737 2.9E-5 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS41425 e6e68c7d9a6dcae2f853226155783257 788 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 737 753 2.9E-5 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS41425 e6e68c7d9a6dcae2f853226155783257 788 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 753 765 2.9E-5 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS41425 e6e68c7d9a6dcae2f853226155783257 788 SUPERFAMILY SSF52540 16 248 6.92E-17 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS13535 cbb1204ba3d2be7e729d20a30534033c 86 Gene3D G3DSA:3.40.430.10 2 82 9.9E-13 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CU254_RS13535 cbb1204ba3d2be7e729d20a30534033c 86 SUPERFAMILY SSF53597 4 77 2.29E-11 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CU254_RS13535 cbb1204ba3d2be7e729d20a30534033c 86 Pfam PF01872 RibD C-terminal domain 4 72 1.7E-7 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CU254_RS10045 4c9985949a56d28c8577dbc2a804bd6d 308 ProSitePatterns PS01125 ROK family signature. 124 151 - T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CU254_RS10045 4c9985949a56d28c8577dbc2a804bd6d 308 SUPERFAMILY SSF53067 1 306 1.82E-60 T 28-03-2018 CU254_RS10045 4c9985949a56d28c8577dbc2a804bd6d 308 Gene3D G3DSA:3.30.420.40 1 108 2.1E-26 T 28-03-2018 CU254_RS10045 4c9985949a56d28c8577dbc2a804bd6d 308 Pfam PF00480 ROK family 1 306 5.3E-73 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CU254_RS10045 4c9985949a56d28c8577dbc2a804bd6d 308 Gene3D G3DSA:3.30.420.40 109 308 3.7E-56 T 28-03-2018 CU254_RS30920 08fe6cca5f3a66eccfae10c4da74c38e 158 Pfam PF00578 AhpC/TSA family 8 136 1.3E-39 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CU254_RS30920 08fe6cca5f3a66eccfae10c4da74c38e 158 PIRSF PIRSF000239 1 155 2.4E-21 T 28-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CU254_RS30920 08fe6cca5f3a66eccfae10c4da74c38e 158 SUPERFAMILY SSF52833 5 154 4.95E-48 T 28-03-2018 IPR012336 Thioredoxin-like fold CU254_RS30920 08fe6cca5f3a66eccfae10c4da74c38e 158 Gene3D G3DSA:3.40.30.10 1 154 5.5E-43 T 28-03-2018 CU254_RS28925 2c5fffd20c0ca6ac6f8f023c826d9fba 392 Gene3D G3DSA:1.10.10.10 130 372 2.9E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS28925 2c5fffd20c0ca6ac6f8f023c826d9fba 392 Pfam PF13556 PucR C-terminal helix-turn-helix domain 322 379 6.3E-21 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CU254_RS08205 5a5898ee39b2c874d339c27307458fb5 100 Pfam PF15580 Immunity protein 53 9 96 1.0E-26 T 28-03-2018 IPR028228 Immunity protein 53 CU254_RS30195 2838b82dbb1024960644dd51a68ef0cd 404 Gene3D G3DSA:3.40.50.2000 219 385 7.8E-32 T 28-03-2018 CU254_RS30195 2838b82dbb1024960644dd51a68ef0cd 404 Pfam PF06722 Protein of unknown function (DUF1205) 192 288 2.2E-18 T 28-03-2018 IPR010610 Domain of unknown function DUF1205 CU254_RS30195 2838b82dbb1024960644dd51a68ef0cd 404 SUPERFAMILY SSF53756 1 42 7.22E-61 T 28-03-2018 CU254_RS30195 2838b82dbb1024960644dd51a68ef0cd 404 SUPERFAMILY SSF53756 74 402 7.22E-61 T 28-03-2018 CU254_RS30195 2838b82dbb1024960644dd51a68ef0cd 404 Gene3D G3DSA:3.40.50.2000 1 218 8.1E-24 T 28-03-2018 CU254_RS16925 456bc5c7b9363241e66d468e38f9b102 284 Gene3D G3DSA:3.30.450.40 94 282 5.8E-54 T 28-03-2018 IPR029016 GAF domain-like CU254_RS16925 456bc5c7b9363241e66d468e38f9b102 284 SUPERFAMILY SSF46785 26 96 4.17E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS16925 456bc5c7b9363241e66d468e38f9b102 284 TIGRFAM TIGR02431 pcaR_pcaU: beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family 22 269 7.7E-90 T 28-03-2018 IPR012794 Beta-ketoadipate transcriptional regulator, PcaR/PcaU/PobR GO:0003677|GO:0045893|GO:0046278 CU254_RS16925 456bc5c7b9363241e66d468e38f9b102 284 SUPERFAMILY SSF55781 91 271 6.21E-48 T 28-03-2018 IPR029016 GAF domain-like CU254_RS16925 456bc5c7b9363241e66d468e38f9b102 284 Pfam PF01614 Bacterial transcriptional regulator 141 267 1.7E-34 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal CU254_RS16925 456bc5c7b9363241e66d468e38f9b102 284 Pfam PF09339 IclR helix-turn-helix domain 28 79 1.9E-15 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS16925 456bc5c7b9363241e66d468e38f9b102 284 SMART SM00346 26 114 3.9E-33 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS16925 456bc5c7b9363241e66d468e38f9b102 284 Gene3D G3DSA:1.10.10.10 17 93 8.8E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS22275 425bd5d78045aec6dc8b7c440115166d 633 SMART SM00939 344 618 8.6E-45 T 28-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CU254_RS22275 425bd5d78045aec6dc8b7c440115166d 633 SUPERFAMILY SSF53474 35 372 1.56E-67 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS22275 425bd5d78045aec6dc8b7c440115166d 633 Gene3D G3DSA:3.40.50.1820 18 372 1.3E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS22275 425bd5d78045aec6dc8b7c440115166d 633 Gene3D G3DSA:2.60.120.260 373 604 7.9E-41 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS22275 425bd5d78045aec6dc8b7c440115166d 633 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 356 598 1.3E-37 T 28-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CU254_RS22275 425bd5d78045aec6dc8b7c440115166d 633 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 57 329 4.3E-53 T 28-03-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 CU254_RS22275 425bd5d78045aec6dc8b7c440115166d 633 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 57 230 2.9E-20 T 28-03-2018 IPR005674 CocE/Serine esterase GO:0016787 CU254_RS22275 425bd5d78045aec6dc8b7c440115166d 633 SUPERFAMILY SSF49785 400 605 1.29E-35 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS13825 ccd531144dfecbf6d71ab62d6770881d 155 Pfam PF01844 HNH endonuclease 80 125 1.8E-7 T 28-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 CU254_RS13825 ccd531144dfecbf6d71ab62d6770881d 155 SMART SM00507 67 117 5.8E-8 T 28-03-2018 IPR003615 HNH nuclease CU254_RS13825 ccd531144dfecbf6d71ab62d6770881d 155 Gene3D G3DSA:3.40.1800.10 59 137 2.9E-15 T 28-03-2018 CU254_RS16615 676bc8b08716be861160c48f58545e58 492 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 6 244 1.3E-27 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CU254_RS16615 676bc8b08716be861160c48f58545e58 492 Gene3D G3DSA:3.30.420.40 6 246 1.2E-47 T 28-03-2018 CU254_RS16615 676bc8b08716be861160c48f58545e58 492 PIRSF PIRSF000538 3 492 1.3E-96 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CU254_RS16615 676bc8b08716be861160c48f58545e58 492 Gene3D G3DSA:3.30.420.40 247 492 2.0E-51 T 28-03-2018 CU254_RS16615 676bc8b08716be861160c48f58545e58 492 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 255 446 2.2E-32 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CU254_RS16615 676bc8b08716be861160c48f58545e58 492 SUPERFAMILY SSF53067 247 485 2.01E-53 T 28-03-2018 CU254_RS16615 676bc8b08716be861160c48f58545e58 492 SUPERFAMILY SSF53067 6 248 3.67E-51 T 28-03-2018 CU254_RS20405 e3a96f3d4f76c02083e20e2c8b783d8a 481 Pfam PF01425 Amidase 58 453 2.1E-78 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS20405 e3a96f3d4f76c02083e20e2c8b783d8a 481 Gene3D G3DSA:3.90.1300.10 2 479 4.1E-115 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS20405 e3a96f3d4f76c02083e20e2c8b783d8a 481 SUPERFAMILY SSF75304 3 463 2.22E-109 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS20405 e3a96f3d4f76c02083e20e2c8b783d8a 481 ProSitePatterns PS00571 Amidases signature. 146 177 - T 28-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CU254_RS21365 7fe3f431606a5b711eeec042180d2f7a 577 Pfam PF00664 ABC transporter transmembrane region 18 288 1.1E-45 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CU254_RS21365 7fe3f431606a5b711eeec042180d2f7a 577 Gene3D G3DSA:1.20.1560.10 1 317 1.6E-70 T 28-03-2018 CU254_RS21365 7fe3f431606a5b711eeec042180d2f7a 577 SUPERFAMILY SSF90123 5 320 1.2E-73 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CU254_RS21365 7fe3f431606a5b711eeec042180d2f7a 577 SMART SM00382 360 546 1.6E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS21365 7fe3f431606a5b711eeec042180d2f7a 577 Gene3D G3DSA:3.40.50.300 326 576 9.4E-71 T 28-03-2018 CU254_RS21365 7fe3f431606a5b711eeec042180d2f7a 577 SUPERFAMILY SSF52540 328 570 8.1E-84 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS21365 7fe3f431606a5b711eeec042180d2f7a 577 Pfam PF00005 ABC transporter 351 498 4.3E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS21365 7fe3f431606a5b711eeec042180d2f7a 577 ProSitePatterns PS00211 ABC transporters family signature. 472 486 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS08565 86866b7f6c2839549292e4f19e2de593 306 Gene3D G3DSA:3.40.366.10 5 139 2.7E-24 T 28-03-2018 CU254_RS08565 86866b7f6c2839549292e4f19e2de593 306 Gene3D G3DSA:3.40.366.10 185 305 1.6E-26 T 28-03-2018 CU254_RS08565 86866b7f6c2839549292e4f19e2de593 306 Pfam PF00698 Acyl transferase domain 11 282 1.0E-23 T 28-03-2018 IPR014043 Acyl transferase CU254_RS08565 86866b7f6c2839549292e4f19e2de593 306 Gene3D G3DSA:3.30.70.250 140 184 7.6E-13 T 28-03-2018 CU254_RS08565 86866b7f6c2839549292e4f19e2de593 306 SUPERFAMILY SSF55048 128 178 1.57E-10 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CU254_RS08565 86866b7f6c2839549292e4f19e2de593 306 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 9 304 3.0E-18 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CU254_RS08565 86866b7f6c2839549292e4f19e2de593 306 SUPERFAMILY SSF52151 182 297 3.66E-61 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CU254_RS08565 86866b7f6c2839549292e4f19e2de593 306 SUPERFAMILY SSF52151 6 120 3.66E-61 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CU254_RS06375 9313dd5c03edabfec2d8d57b37f34a90 137 Pfam PF02627 Carboxymuconolactone decarboxylase family 14 80 2.9E-18 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CU254_RS06375 9313dd5c03edabfec2d8d57b37f34a90 137 Gene3D G3DSA:1.20.1290.10 1 137 2.4E-33 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CU254_RS06375 9313dd5c03edabfec2d8d57b37f34a90 137 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 16 64 1.4E-18 T 28-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CU254_RS06375 9313dd5c03edabfec2d8d57b37f34a90 137 SUPERFAMILY SSF69118 11 131 2.09E-37 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CU254_RS17755 3cefac1a483190b37160b76e79460364 458 Gene3D G3DSA:3.40.50.2000 266 433 9.2E-32 T 28-03-2018 CU254_RS17755 3cefac1a483190b37160b76e79460364 458 Gene3D G3DSA:3.40.50.2000 81 265 3.1E-14 T 28-03-2018 CU254_RS17755 3cefac1a483190b37160b76e79460364 458 Pfam PF00534 Glycosyl transferases group 1 275 425 2.7E-26 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CU254_RS17755 3cefac1a483190b37160b76e79460364 458 Pfam PF13439 Glycosyltransferase Family 4 99 261 1.9E-25 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CU254_RS17755 3cefac1a483190b37160b76e79460364 458 SUPERFAMILY SSF53756 89 444 5.13E-67 T 28-03-2018 CU254_RS41110 8ec98706f97c5066e85d7a32ca67e78f 393 Gene3D G3DSA:3.40.50.2000 11 198 5.6E-36 T 28-03-2018 CU254_RS41110 8ec98706f97c5066e85d7a32ca67e78f 393 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 215 382 4.3E-33 T 28-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CU254_RS41110 8ec98706f97c5066e85d7a32ca67e78f 393 Gene3D G3DSA:3.40.50.2000 199 374 1.4E-29 T 28-03-2018 CU254_RS41110 8ec98706f97c5066e85d7a32ca67e78f 393 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 16 390 30.275 T 28-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CU254_RS41110 8ec98706f97c5066e85d7a32ca67e78f 393 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 16 165 6.0E-28 T 28-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CU254_RS41110 8ec98706f97c5066e85d7a32ca67e78f 393 SUPERFAMILY SSF53756 15 390 5.16E-88 T 28-03-2018 CU254_RS01620 df4ef659a0493b2391041957a53113bf 162 Gene3D G3DSA:3.10.180.10 28 140 9.0E-8 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS01620 df4ef659a0493b2391041957a53113bf 162 SUPERFAMILY SSF54593 30 136 1.45E-10 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS18635 00aa8bfd8c2f80433ef808f9d8292084 252 Pfam PF09339 IclR helix-turn-helix domain 15 64 3.9E-10 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS18635 00aa8bfd8c2f80433ef808f9d8292084 252 Pfam PF01614 Bacterial transcriptional regulator 128 247 4.8E-23 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal CU254_RS18635 00aa8bfd8c2f80433ef808f9d8292084 252 SUPERFAMILY SSF55781 86 250 5.36E-39 T 28-03-2018 IPR029016 GAF domain-like CU254_RS18635 00aa8bfd8c2f80433ef808f9d8292084 252 Gene3D G3DSA:3.30.450.40 77 252 1.3E-45 T 28-03-2018 IPR029016 GAF domain-like CU254_RS18635 00aa8bfd8c2f80433ef808f9d8292084 252 Gene3D G3DSA:1.10.10.10 2 72 1.3E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS18635 00aa8bfd8c2f80433ef808f9d8292084 252 SUPERFAMILY SSF46785 13 76 2.68E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS18635 00aa8bfd8c2f80433ef808f9d8292084 252 SMART SM00346 13 101 4.1E-10 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS08550 1caebc138914382a828b5c77c08d0731 416 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 5 253 1.2E-55 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CU254_RS08550 1caebc138914382a828b5c77c08d0731 416 PIRSF PIRSF000447 1 416 7.0E-140 T 28-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 CU254_RS08550 1caebc138914382a828b5c77c08d0731 416 SUPERFAMILY SSF53901 5 258 2.27E-64 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS08550 1caebc138914382a828b5c77c08d0731 416 Gene3D G3DSA:3.40.47.10 269 416 2.6E-42 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS08550 1caebc138914382a828b5c77c08d0731 416 Gene3D G3DSA:3.40.47.10 6 266 4.5E-67 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS08550 1caebc138914382a828b5c77c08d0731 416 SMART SM00825 Beta-ketoacyl synthase 6 406 1.3E-13 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CU254_RS08550 1caebc138914382a828b5c77c08d0731 416 SUPERFAMILY SSF53901 221 414 3.67E-62 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS08550 1caebc138914382a828b5c77c08d0731 416 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 261 372 4.2E-28 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CU254_RS37225 6b4016779b64fba84aabc491247c80f0 480 Pfam PF07690 Major Facilitator Superfamily 26 410 1.1E-41 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS37225 6b4016779b64fba84aabc491247c80f0 480 Gene3D G3DSA:1.20.1250.20 3 197 3.3E-28 T 28-03-2018 CU254_RS37225 6b4016779b64fba84aabc491247c80f0 480 SUPERFAMILY SSF103473 251 420 1.96E-60 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS37225 6b4016779b64fba84aabc491247c80f0 480 SUPERFAMILY SSF103473 8 202 1.96E-60 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS37225 6b4016779b64fba84aabc491247c80f0 480 SUPERFAMILY SSF103473 454 478 1.96E-60 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS37225 6b4016779b64fba84aabc491247c80f0 480 Gene3D G3DSA:1.20.1250.20 262 480 1.6E-21 T 28-03-2018 CU254_RS30805 85339d5707f9bb1fc1f0b3d7ccfdbf68 298 SUPERFAMILY SSF51735 5 254 4.18E-58 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS30805 85339d5707f9bb1fc1f0b3d7ccfdbf68 298 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS30805 85339d5707f9bb1fc1f0b3d7ccfdbf68 298 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 1.4E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS30805 85339d5707f9bb1fc1f0b3d7ccfdbf68 298 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 1.4E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS30805 85339d5707f9bb1fc1f0b3d7ccfdbf68 298 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.4E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS30805 85339d5707f9bb1fc1f0b3d7ccfdbf68 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 3.5E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS30805 85339d5707f9bb1fc1f0b3d7ccfdbf68 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 3.5E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS30805 85339d5707f9bb1fc1f0b3d7ccfdbf68 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 3.5E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS30805 85339d5707f9bb1fc1f0b3d7ccfdbf68 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.5E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS30805 85339d5707f9bb1fc1f0b3d7ccfdbf68 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 3.5E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS30805 85339d5707f9bb1fc1f0b3d7ccfdbf68 298 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 202 222 3.5E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS30805 85339d5707f9bb1fc1f0b3d7ccfdbf68 298 Gene3D G3DSA:3.40.50.720 159 239 2.2E-16 T 28-03-2018 CU254_RS30805 85339d5707f9bb1fc1f0b3d7ccfdbf68 298 Pfam PF00106 short chain dehydrogenase 9 195 1.3E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS30805 85339d5707f9bb1fc1f0b3d7ccfdbf68 298 Gene3D G3DSA:3.40.50.720 4 158 4.1E-35 T 28-03-2018 CU254_RS07835 0ac784edec974ed48b58aa3b70e9728f 105 Gene3D G3DSA:2.60.40.180 1 105 4.0E-35 T 28-03-2018 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 CU254_RS07835 0ac784edec974ed48b58aa3b70e9728f 105 SUPERFAMILY SSF49472 1 105 1.27E-32 T 28-03-2018 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 CU254_RS07835 0ac784edec974ed48b58aa3b70e9728f 105 TIGRFAM TIGR02962 hdxy_isourate: hydroxyisourate hydrolase 2 105 4.3E-31 T 28-03-2018 IPR014306 Hydroxyisourate hydrolase GO:0006144|GO:0033971 KEGG: 00230+3.5.2.17|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 CU254_RS07835 0ac784edec974ed48b58aa3b70e9728f 105 ProSitePatterns PS00768 Transthyretin signature 1. 7 22 - T 28-03-2018 IPR023418 Transthyretin, thyroxine binding site Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 CU254_RS07835 0ac784edec974ed48b58aa3b70e9728f 105 Pfam PF00576 HIUase/Transthyretin family 4 104 1.6E-30 T 28-03-2018 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 CU254_RS07835 0ac784edec974ed48b58aa3b70e9728f 105 PRINTS PR00189 Transthyretin signature 3 23 1.9E-8 T 28-03-2018 IPR000895 Transthyretin/hydroxyisourate hydrolase Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 CU254_RS07835 0ac784edec974ed48b58aa3b70e9728f 105 PRINTS PR00189 Transthyretin signature 83 105 1.9E-8 T 28-03-2018 IPR000895 Transthyretin/hydroxyisourate hydrolase Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 CU254_RS38990 b372b196c67cafe6d06d2ac30d56dee6 410 Pfam PF07690 Major Facilitator Superfamily 28 297 1.1E-23 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS38990 b372b196c67cafe6d06d2ac30d56dee6 410 SUPERFAMILY SSF103473 17 391 1.26E-41 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS38990 b372b196c67cafe6d06d2ac30d56dee6 410 ProSitePatterns PS00216 Sugar transport proteins signature 1. 65 81 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CU254_RS38990 b372b196c67cafe6d06d2ac30d56dee6 410 Gene3D G3DSA:1.20.1250.20 206 396 8.0E-16 T 28-03-2018 CU254_RS38990 b372b196c67cafe6d06d2ac30d56dee6 410 Gene3D G3DSA:1.20.1250.20 11 196 2.6E-25 T 28-03-2018 CU254_RS30870 b41e99c1129019814ac03c1eb1c928e5 121 Pfam PF13411 MerR HTH family regulatory protein 2 63 2.1E-21 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS30870 b41e99c1129019814ac03c1eb1c928e5 121 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS30870 b41e99c1129019814ac03c1eb1c928e5 121 SMART SM00422 1 69 7.2E-21 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS30870 b41e99c1129019814ac03c1eb1c928e5 121 SUPERFAMILY SSF46955 2 113 1.28E-26 T 28-03-2018 IPR009061 Putative DNA-binding domain CU254_RS30870 b41e99c1129019814ac03c1eb1c928e5 121 Gene3D G3DSA:1.10.1660.10 54 119 2.3E-10 T 28-03-2018 CU254_RS30870 b41e99c1129019814ac03c1eb1c928e5 121 Gene3D G3DSA:1.10.1660.10 1 53 3.4E-23 T 28-03-2018 CU254_RS30870 b41e99c1129019814ac03c1eb1c928e5 121 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 1.3E-10 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS30870 b41e99c1129019814ac03c1eb1c928e5 121 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 1.3E-10 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS30870 b41e99c1129019814ac03c1eb1c928e5 121 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 1.3E-10 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS22560 7395cdab22eba0160bf5401056c614b0 427 SUPERFAMILY SSF53850 17 426 3.89E-80 T 28-03-2018 CU254_RS22560 7395cdab22eba0160bf5401056c614b0 427 Gene3D G3DSA:3.40.190.10 168 427 5.8E-48 T 28-03-2018 CU254_RS22560 7395cdab22eba0160bf5401056c614b0 427 Gene3D G3DSA:3.40.190.10 36 167 2.2E-24 T 28-03-2018 CU254_RS22560 7395cdab22eba0160bf5401056c614b0 427 Pfam PF01547 Bacterial extracellular solute-binding protein 52 341 1.6E-35 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 CU254_RS39715 5a2a10943b41cf346af9cfe17a5f552b 1724 Gene3D G3DSA:1.10.287.850 78 165 1.2E-14 T 28-03-2018 CU254_RS39715 5a2a10943b41cf346af9cfe17a5f552b 1724 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 803 835 0.0012 T 28-03-2018 IPR006530 YD repeat CU254_RS39715 5a2a10943b41cf346af9cfe17a5f552b 1724 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1122 1149 1.5E-5 T 28-03-2018 IPR006530 YD repeat CU254_RS39715 5a2a10943b41cf346af9cfe17a5f552b 1724 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 655 691 0.0034 T 28-03-2018 IPR006530 YD repeat CU254_RS39715 5a2a10943b41cf346af9cfe17a5f552b 1724 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 824 864 1.2E-11 T 28-03-2018 IPR006530 YD repeat CU254_RS39715 5a2a10943b41cf346af9cfe17a5f552b 1724 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 618 651 6.3E-5 T 28-03-2018 IPR006530 YD repeat CU254_RS39715 5a2a10943b41cf346af9cfe17a5f552b 1724 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 549 584 3.8E-6 T 28-03-2018 IPR006530 YD repeat CU254_RS39715 5a2a10943b41cf346af9cfe17a5f552b 1724 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 866 903 8.5E-6 T 28-03-2018 IPR006530 YD repeat CU254_RS39715 5a2a10943b41cf346af9cfe17a5f552b 1724 SUPERFAMILY SSF69304 820 1017 7.19E-5 T 28-03-2018 CU254_RS39715 5a2a10943b41cf346af9cfe17a5f552b 1724 SUPERFAMILY SSF140453 86 161 1.23E-7 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CU254_RS39715 5a2a10943b41cf346af9cfe17a5f552b 1724 SUPERFAMILY SSF69304 549 709 1.44E-5 T 28-03-2018 CU254_RS39715 5a2a10943b41cf346af9cfe17a5f552b 1724 Pfam PF06013 Proteins of 100 residues with WXG 87 161 1.1E-6 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CU254_RS39715 5a2a10943b41cf346af9cfe17a5f552b 1724 Pfam PF05593 RHS Repeat 824 861 2.9E-11 T 28-03-2018 IPR031325 RHS repeat CU254_RS39715 5a2a10943b41cf346af9cfe17a5f552b 1724 Pfam PF05593 RHS Repeat 570 599 6.1E-7 T 28-03-2018 IPR031325 RHS repeat CU254_RS39715 5a2a10943b41cf346af9cfe17a5f552b 1724 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1245 1306 1.3E-18 T 28-03-2018 IPR022385 Rhs repeat-associated core GO:0097264 CU254_RS39715 5a2a10943b41cf346af9cfe17a5f552b 1724 Pfam PF03527 RHS protein 1213 1241 1.2E-7 T 28-03-2018 IPR001826 RHS protein CU254_RS29260 8186625e16a996bf043dd7ae134ee4a9 320 SUPERFAMILY SSF50475 11 162 1.32E-44 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS29260 8186625e16a996bf043dd7ae134ee4a9 320 Gene3D G3DSA:1.20.120.530 177 318 8.0E-23 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS29260 8186625e16a996bf043dd7ae134ee4a9 320 Pfam PF01613 Flavin reductase like domain 16 162 6.7E-35 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CU254_RS29260 8186625e16a996bf043dd7ae134ee4a9 320 Gene3D G3DSA:2.30.110.10 3 176 1.5E-39 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS29260 8186625e16a996bf043dd7ae134ee4a9 320 SMART SM00895 192 313 6.4E-19 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS29260 8186625e16a996bf043dd7ae134ee4a9 320 SUPERFAMILY SSF48008 191 316 1.94E-20 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS29260 8186625e16a996bf043dd7ae134ee4a9 320 Pfam PF07729 FCD domain 192 311 2.0E-22 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS29260 8186625e16a996bf043dd7ae134ee4a9 320 SMART SM00903 15 161 8.8E-51 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CU254_RS10440 52d339237eb05d32e448d5af00d770bc 391 SUPERFAMILY SSF50022 21 133 2.49E-28 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CU254_RS10440 52d339237eb05d32e448d5af00d770bc 391 Gene3D G3DSA:3.90.380.10 128 348 4.8E-31 T 28-03-2018 CU254_RS10440 52d339237eb05d32e448d5af00d770bc 391 Pfam PF00355 Rieske [2Fe-2S] domain 26 108 1.2E-16 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CU254_RS10440 52d339237eb05d32e448d5af00d770bc 391 SUPERFAMILY SSF55961 127 346 1.29E-30 T 28-03-2018 CU254_RS10440 52d339237eb05d32e448d5af00d770bc 391 Gene3D G3DSA:2.102.10.10 23 127 7.8E-24 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CU254_RS21815 c97dc5d161926763c2d0ce407f753378 264 Gene3D G3DSA:3.40.50.80 136 263 4.9E-36 T 28-03-2018 CU254_RS21815 c97dc5d161926763c2d0ce407f753378 264 Pfam PF08021 Siderophore-interacting FAD-binding domain 20 132 1.9E-27 T 28-03-2018 IPR013113 FAD-binding 9, siderophore-interacting CU254_RS21815 c97dc5d161926763c2d0ce407f753378 264 Gene3D G3DSA:2.40.30.10 8 135 3.1E-30 T 28-03-2018 CU254_RS21815 c97dc5d161926763c2d0ce407f753378 264 SUPERFAMILY SSF63380 13 130 2.67E-7 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CU254_RS21815 c97dc5d161926763c2d0ce407f753378 264 Pfam PF04954 Siderophore-interacting protein 144 259 9.1E-29 T 28-03-2018 IPR007037 Siderophore-interacting protein CU254_RS30345 205aeec297a253391d5f2789f3619ec0 357 Pfam PF06271 RDD family 201 334 2.0E-11 T 28-03-2018 IPR010432 RDD CU254_RS30345 205aeec297a253391d5f2789f3619ec0 357 Pfam PF04892 VanZ like family 48 183 3.2E-17 T 28-03-2018 IPR006976 VanZ-like CU254_RS36145 cd0022ee400a67d2d86162179c167474 246 Gene3D G3DSA:3.40.50.1820 5 246 1.8E-39 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS36145 cd0022ee400a67d2d86162179c167474 246 SUPERFAMILY SSF53474 10 243 9.13E-46 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS36145 cd0022ee400a67d2d86162179c167474 246 Pfam PF12697 Alpha/beta hydrolase family 14 234 9.4E-18 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS35205 e427abf5984b8e028f726a0de0e23cc2 275 Gene3D G3DSA:1.10.3720.10 52 268 7.0E-37 T 28-03-2018 CU254_RS35205 e427abf5984b8e028f726a0de0e23cc2 275 TIGRFAM TIGR01581 Mo_ABC_porter: NifC-like ABC-type porter 40 261 9.2E-73 T 28-03-2018 IPR006469 NifC-like ABC-type porter GO:0005215|GO:0006810|GO:0016020 CU254_RS35205 e427abf5984b8e028f726a0de0e23cc2 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 263 1.9E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS35205 e427abf5984b8e028f726a0de0e23cc2 275 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 64 265 1.8E-63 T 28-03-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 CU254_RS35205 e427abf5984b8e028f726a0de0e23cc2 275 SUPERFAMILY SSF161098 18 265 2.83E-48 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS08090 0da97b80e06e744f384e1a3cf4e4fe87 550 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 41 52 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CU254_RS08090 0da97b80e06e744f384e1a3cf4e4fe87 550 Gene3D G3DSA:1.10.1160.10 288 370 4.2E-8 T 28-03-2018 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 CU254_RS08090 0da97b80e06e744f384e1a3cf4e4fe87 550 SUPERFAMILY SSF52374 36 323 9.7E-67 T 28-03-2018 CU254_RS08090 0da97b80e06e744f384e1a3cf4e4fe87 550 PRINTS PR00987 Glutamyl-tRNA synthetase signature 38 50 6.0E-15 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CU254_RS08090 0da97b80e06e744f384e1a3cf4e4fe87 550 PRINTS PR00987 Glutamyl-tRNA synthetase signature 248 256 6.0E-15 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CU254_RS08090 0da97b80e06e744f384e1a3cf4e4fe87 550 PRINTS PR00987 Glutamyl-tRNA synthetase signature 67 80 6.0E-15 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CU254_RS08090 0da97b80e06e744f384e1a3cf4e4fe87 550 PRINTS PR00987 Glutamyl-tRNA synthetase signature 232 242 6.0E-15 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CU254_RS08090 0da97b80e06e744f384e1a3cf4e4fe87 550 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 36 322 5.3E-60 T 28-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 CU254_RS08090 0da97b80e06e744f384e1a3cf4e4fe87 550 Gene3D G3DSA:3.40.50.620 171 284 9.8E-21 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS08090 0da97b80e06e744f384e1a3cf4e4fe87 550 SUPERFAMILY SSF48163 355 547 5.49E-13 T 28-03-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CU254_RS08090 0da97b80e06e744f384e1a3cf4e4fe87 550 Gene3D G3DSA:1.10.10.350 446 547 1.4E-13 T 28-03-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CU254_RS08090 0da97b80e06e744f384e1a3cf4e4fe87 550 Gene3D G3DSA:3.40.50.620 30 170 6.2E-26 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS09660 f3789d5fddd2d2d8559e7ffc401f1484 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 82 265 3.4E-23 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS09660 f3789d5fddd2d2d8559e7ffc401f1484 294 SUPERFAMILY SSF161098 61 266 6.54E-41 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS09660 f3789d5fddd2d2d8559e7ffc401f1484 294 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 61 156 2.5E-24 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CU254_RS09660 f3789d5fddd2d2d8559e7ffc401f1484 294 Gene3D G3DSA:1.10.3720.10 18 270 3.3E-43 T 28-03-2018 CU254_RS22850 17c32e1d4f93b3a296a822eed4121984 283 SUPERFAMILY SSF53335 38 261 1.51E-37 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS22850 17c32e1d4f93b3a296a822eed4121984 283 Gene3D G3DSA:3.40.50.150 67 282 1.9E-31 T 28-03-2018 CU254_RS22850 17c32e1d4f93b3a296a822eed4121984 283 Pfam PF13649 Methyltransferase domain 85 177 1.1E-18 T 28-03-2018 CU254_RS17000 918efe96217ac3355e81571016b9a4dd 137 Pfam PF12680 SnoaL-like domain 13 120 9.0E-19 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CU254_RS17000 918efe96217ac3355e81571016b9a4dd 137 Gene3D G3DSA:3.10.450.50 1 136 4.5E-25 T 28-03-2018 CU254_RS17000 918efe96217ac3355e81571016b9a4dd 137 SUPERFAMILY SSF54427 6 127 7.45E-26 T 28-03-2018 IPR032710 NTF2-like domain CU254_RS22350 d0e646736fc885f1ff5cadb984e2ff0d 633 SUPERFAMILY SSF54556 363 433 5.07E-7 T 28-03-2018 IPR029070 Chitinase insertion domain CU254_RS22350 d0e646736fc885f1ff5cadb984e2ff0d 633 Gene3D G3DSA:2.10.10.20 582 633 3.8E-15 T 28-03-2018 CU254_RS22350 d0e646736fc885f1ff5cadb984e2ff0d 633 Gene3D G3DSA:2.10.10.20 517 578 4.1E-19 T 28-03-2018 CU254_RS22350 d0e646736fc885f1ff5cadb984e2ff0d 633 SUPERFAMILY SSF51055 586 633 6.67E-14 T 28-03-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 CU254_RS22350 d0e646736fc885f1ff5cadb984e2ff0d 633 SMART SM00495 588 630 3.6E-11 T 28-03-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 CU254_RS22350 d0e646736fc885f1ff5cadb984e2ff0d 633 SMART SM00495 532 574 2.0E-16 T 28-03-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 CU254_RS22350 d0e646736fc885f1ff5cadb984e2ff0d 633 SUPERFAMILY SSF51445 37 361 2.11E-72 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS22350 d0e646736fc885f1ff5cadb984e2ff0d 633 SUPERFAMILY SSF51445 433 485 2.11E-72 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS22350 d0e646736fc885f1ff5cadb984e2ff0d 633 Pfam PF00704 Glycosyl hydrolases family 18 46 460 2.2E-70 T 28-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 CU254_RS22350 d0e646736fc885f1ff5cadb984e2ff0d 633 SMART SM00636 43 466 3.3E-90 T 28-03-2018 IPR011583 Chitinase II GO:0008061 CU254_RS22350 d0e646736fc885f1ff5cadb984e2ff0d 633 Gene3D G3DSA:3.20.20.80 7 486 4.3E-77 T 28-03-2018 CU254_RS22350 d0e646736fc885f1ff5cadb984e2ff0d 633 Pfam PF02839 Carbohydrate binding domain 549 571 8.0E-5 T 28-03-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 CU254_RS22350 d0e646736fc885f1ff5cadb984e2ff0d 633 ProSitePatterns PS01095 Chitinases family 18 active site. 213 221 - T 28-03-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 CU254_RS22350 d0e646736fc885f1ff5cadb984e2ff0d 633 SUPERFAMILY SSF51055 528 577 2.75E-16 T 28-03-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 CU254_RS26710 4f6bd9610f21592b9e3f640423878366 323 Gene3D G3DSA:3.40.50.300 2 127 2.4E-12 T 28-03-2018 CU254_RS26710 4f6bd9610f21592b9e3f640423878366 323 SUPERFAMILY SSF52540 5 179 9.56E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS26710 4f6bd9610f21592b9e3f640423878366 323 Pfam PF06144 DNA polymerase III, delta subunit 9 172 1.8E-8 T 28-03-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 CU254_RS26710 4f6bd9610f21592b9e3f640423878366 323 Gene3D G3DSA:1.20.272.10 208 323 6.0E-22 T 28-03-2018 CU254_RS26710 4f6bd9610f21592b9e3f640423878366 323 Gene3D G3DSA:1.10.8.60 132 207 7.2E-11 T 28-03-2018 CU254_RS26710 4f6bd9610f21592b9e3f640423878366 323 SUPERFAMILY SSF48019 200 315 1.04E-11 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CU254_RS05480 de7fe8f417c6b9198de4229d2bd1554d 226 SUPERFAMILY SSF46689 15 75 8.48E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS05480 de7fe8f417c6b9198de4229d2bd1554d 226 Gene3D G3DSA:1.10.357.10 1 224 5.9E-42 T 28-03-2018 CU254_RS05480 de7fe8f417c6b9198de4229d2bd1554d 226 SUPERFAMILY SSF48498 85 221 6.56E-26 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS05480 de7fe8f417c6b9198de4229d2bd1554d 226 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 83 218 9.5E-12 T 28-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 CU254_RS05480 de7fe8f417c6b9198de4229d2bd1554d 226 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 67 7.6E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS13860 43b44ef74a8dc20494fa73464c020783 297 SUPERFAMILY SSF51735 2 252 8.08E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS13860 43b44ef74a8dc20494fa73464c020783 297 Gene3D G3DSA:3.40.50.720 1 147 3.6E-18 T 28-03-2018 CU254_RS13860 43b44ef74a8dc20494fa73464c020783 297 Pfam PF13460 NAD(P)H-binding 8 151 8.6E-19 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS35440 6415390a861650941f123551eab86d06 143 Gene3D G3DSA:1.10.357.10 23 141 5.6E-19 T 28-03-2018 CU254_RS35440 6415390a861650941f123551eab86d06 143 SUPERFAMILY SSF48498 27 138 5.89E-16 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS35440 6415390a861650941f123551eab86d06 143 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 38 138 2.9E-8 T 28-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 CU254_RS29530 97ae84d045e9cb888a61f87e2ca701cc 912 SUPERFAMILY SSF53649 511 779 1.81E-5 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CU254_RS29530 97ae84d045e9cb888a61f87e2ca701cc 912 SUPERFAMILY SSF50969 79 245 9.81E-27 T 28-03-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like CU254_RS29530 97ae84d045e9cb888a61f87e2ca701cc 912 SUPERFAMILY SSF50969 274 371 9.81E-27 T 28-03-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like CU254_RS29530 97ae84d045e9cb888a61f87e2ca701cc 912 Gene3D G3DSA:3.40.720.10 474 786 1.7E-17 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CU254_RS29530 97ae84d045e9cb888a61f87e2ca701cc 912 Gene3D G3DSA:2.130.10.10 266 458 2.5E-16 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CU254_RS29530 97ae84d045e9cb888a61f87e2ca701cc 912 Gene3D G3DSA:2.130.10.10 179 265 3.5E-9 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CU254_RS29530 97ae84d045e9cb888a61f87e2ca701cc 912 Gene3D G3DSA:2.130.10.10 69 178 1.5E-7 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CU254_RS29530 97ae84d045e9cb888a61f87e2ca701cc 912 Pfam PF04185 Phosphoesterase family 694 776 4.6E-6 T 28-03-2018 IPR007312 Phosphoesterase GO:0016788 CU254_RS23145 f238e530e6596877dcc2711bcf4d33a6 421 Pfam PF05193 Peptidase M16 inactive domain 164 338 1.0E-18 T 28-03-2018 IPR007863 Peptidase M16, C-terminal CU254_RS23145 f238e530e6596877dcc2711bcf4d33a6 421 SUPERFAMILY SSF63411 238 404 5.06E-26 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CU254_RS23145 f238e530e6596877dcc2711bcf4d33a6 421 SUPERFAMILY SSF63411 7 214 1.03E-26 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CU254_RS23145 f238e530e6596877dcc2711bcf4d33a6 421 Gene3D G3DSA:3.30.830.10 9 211 4.5E-25 T 28-03-2018 CU254_RS23145 f238e530e6596877dcc2711bcf4d33a6 421 Gene3D G3DSA:3.30.830.10 234 416 3.3E-22 T 28-03-2018 CU254_RS19840 3381ed1d9dd23524416f3b16e14f5605 246 Gene3D G3DSA:3.40.50.720 186 243 0.0045 T 28-03-2018 CU254_RS19840 3381ed1d9dd23524416f3b16e14f5605 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.2E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS19840 3381ed1d9dd23524416f3b16e14f5605 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 2.2E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS19840 3381ed1d9dd23524416f3b16e14f5605 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 2.2E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS19840 3381ed1d9dd23524416f3b16e14f5605 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 2.2E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS19840 3381ed1d9dd23524416f3b16e14f5605 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 2.2E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS19840 3381ed1d9dd23524416f3b16e14f5605 246 Gene3D G3DSA:3.40.50.720 1 185 1.7E-54 T 28-03-2018 CU254_RS19840 3381ed1d9dd23524416f3b16e14f5605 246 SUPERFAMILY SSF51735 4 239 1.11E-63 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS19840 3381ed1d9dd23524416f3b16e14f5605 246 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 190 0.0079 T 28-03-2018 CU254_RS19840 3381ed1d9dd23524416f3b16e14f5605 246 Pfam PF00106 short chain dehydrogenase 7 197 2.3E-52 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS19840 3381ed1d9dd23524416f3b16e14f5605 246 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS39500 033ed215ac2c3f2e63fb3c44d82a8ebf 487 SUPERFAMILY SSF56601 139 482 5.64E-79 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CU254_RS39500 033ed215ac2c3f2e63fb3c44d82a8ebf 487 Gene3D G3DSA:3.90.1310.10 17 141 7.1E-23 T 28-03-2018 CU254_RS39500 033ed215ac2c3f2e63fb3c44d82a8ebf 487 SUPERFAMILY SSF56519 73 135 3.92E-5 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CU254_RS39500 033ed215ac2c3f2e63fb3c44d82a8ebf 487 Gene3D G3DSA:3.40.710.10 142 486 5.1E-84 T 28-03-2018 CU254_RS39500 033ed215ac2c3f2e63fb3c44d82a8ebf 487 Pfam PF00905 Penicillin binding protein transpeptidase domain 158 479 7.4E-67 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CU254_RS35085 8ed110f7f27c0ba2301bfcbf21f68a6c 418 SUPERFAMILY SSF103473 8 400 1.44E-50 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS35085 8ed110f7f27c0ba2301bfcbf21f68a6c 418 Pfam PF05977 Transmembrane secretion effector 2 396 2.3E-55 T 28-03-2018 IPR010290 Transmembrane secretion effector CU254_RS35085 8ed110f7f27c0ba2301bfcbf21f68a6c 418 Gene3D G3DSA:1.20.1250.20 1 208 3.2E-19 T 28-03-2018 CU254_RS35085 8ed110f7f27c0ba2301bfcbf21f68a6c 418 Gene3D G3DSA:1.20.1250.20 209 402 5.8E-22 T 28-03-2018 CU254_RS10205 1677a6ff94c7756c9553ada348797ca6 173 Pfam PF13302 Acetyltransferase (GNAT) domain 6 143 5.5E-16 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS10205 1677a6ff94c7756c9553ada348797ca6 173 SUPERFAMILY SSF55729 3 167 3.31E-33 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS10205 1677a6ff94c7756c9553ada348797ca6 173 Gene3D G3DSA:3.40.630.30 1 173 1.1E-30 T 28-03-2018 CU254_RS30970 310dee836f242d2cabd97b549def589d 440 SUPERFAMILY SSF103473 4 189 1.7E-24 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS30970 310dee836f242d2cabd97b549def589d 440 PRINTS PR01035 Tetracycline resistance protein signature 18 34 6.0E-6 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CU254_RS30970 310dee836f242d2cabd97b549def589d 440 PRINTS PR01035 Tetracycline resistance protein signature 132 154 6.0E-6 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CU254_RS30970 310dee836f242d2cabd97b549def589d 440 PRINTS PR01035 Tetracycline resistance protein signature 257 277 6.0E-6 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CU254_RS30970 310dee836f242d2cabd97b549def589d 440 SUPERFAMILY SSF103473 195 435 5.49E-25 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS30970 310dee836f242d2cabd97b549def589d 440 Gene3D G3DSA:1.20.1250.20 248 438 8.9E-23 T 28-03-2018 CU254_RS30970 310dee836f242d2cabd97b549def589d 440 Pfam PF07690 Major Facilitator Superfamily 12 396 8.5E-39 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS30970 310dee836f242d2cabd97b549def589d 440 Gene3D G3DSA:1.20.1250.20 3 191 6.4E-21 T 28-03-2018 CU254_RS24265 ac6858530b04a9fce4413d27c860a7c6 303 SUPERFAMILY SSF48317 30 219 1.96E-13 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CU254_RS24265 ac6858530b04a9fce4413d27c860a7c6 303 Pfam PF01569 PAP2 superfamily 141 216 1.0E-10 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CU254_RS24265 ac6858530b04a9fce4413d27c860a7c6 303 Gene3D G3DSA:1.20.144.10 18 225 9.3E-10 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CU254_RS10140 acca872cf99d9dc1c4c3773e445b4f6b 101 SUPERFAMILY SSF46785 3 96 5.89E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS10140 acca872cf99d9dc1c4c3773e445b4f6b 101 Gene3D G3DSA:1.10.10.10 1 101 4.2E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS10140 acca872cf99d9dc1c4c3773e445b4f6b 101 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 5 20 7.1E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS10140 acca872cf99d9dc1c4c3773e445b4f6b 101 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 37 52 7.1E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS10140 acca872cf99d9dc1c4c3773e445b4f6b 101 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 67 7.1E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS10140 acca872cf99d9dc1c4c3773e445b4f6b 101 Pfam PF01022 Bacterial regulatory protein, arsR family 11 55 1.0E-16 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS10140 acca872cf99d9dc1c4c3773e445b4f6b 101 SMART SM00418 3 81 1.6E-24 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS30930 7483d9f4b88fc8bab6552c5344123da9 279 Gene3D G3DSA:1.10.10.60 208 266 2.2E-11 T 28-03-2018 CU254_RS30930 7483d9f4b88fc8bab6552c5344123da9 279 SMART SM00342 172 256 2.4E-6 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS30930 7483d9f4b88fc8bab6552c5344123da9 279 Gene3D G3DSA:1.10.10.60 105 207 9.9E-7 T 28-03-2018 CU254_RS30930 7483d9f4b88fc8bab6552c5344123da9 279 Pfam PF12833 Helix-turn-helix domain 178 256 3.8E-14 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS30930 7483d9f4b88fc8bab6552c5344123da9 279 SUPERFAMILY SSF46689 219 256 7.17E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS19430 919150af7d6249a6dfaf9ec4ecb3e43f 268 Pfam PF11296 Protein of unknown function (DUF3097) 4 262 2.7E-122 T 28-03-2018 IPR021447 Protein of unknown function DUF3097 CU254_RS27140 7464eab3d0f92d5701519d4ed609598e 279 Pfam PF13560 Helix-turn-helix domain 6 84 4.9E-15 T 28-03-2018 CU254_RS27140 7464eab3d0f92d5701519d4ed609598e 279 SMART SM00530 9 81 2.1E-5 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS27140 7464eab3d0f92d5701519d4ed609598e 279 Gene3D G3DSA:1.10.260.40 1 90 1.8E-15 T 28-03-2018 CU254_RS27140 7464eab3d0f92d5701519d4ed609598e 279 SUPERFAMILY SSF47413 28 80 1.38E-7 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS07435 3df40f3867d6e3ec22695619fdc12dc2 443 Gene3D G3DSA:3.40.640.10 121 318 9.4E-36 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS07435 3df40f3867d6e3ec22695619fdc12dc2 443 SMART SM00345 7 66 2.1E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS07435 3df40f3867d6e3ec22695619fdc12dc2 443 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 66 1.9E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS07435 3df40f3867d6e3ec22695619fdc12dc2 443 SUPERFAMILY SSF53383 100 431 3.71E-63 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS07435 3df40f3867d6e3ec22695619fdc12dc2 443 SUPERFAMILY SSF46785 4 70 8.16E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS07435 3df40f3867d6e3ec22695619fdc12dc2 443 Gene3D G3DSA:3.90.1150.10 319 433 3.0E-14 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS07435 3df40f3867d6e3ec22695619fdc12dc2 443 Pfam PF00155 Aminotransferase class I and II 125 427 1.6E-17 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CU254_RS07435 3df40f3867d6e3ec22695619fdc12dc2 443 Gene3D G3DSA:1.10.10.10 2 68 8.3E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS29970 8f418e90fb7a314646a124a9291e6752 1116 TIGRFAM TIGR03491 TIGR03491: putative RecB family nuclease, TM0106 family 3 482 1.2E-64 T 28-03-2018 IPR019993 RecB family nuclease, TM0106, putative CU254_RS29970 8f418e90fb7a314646a124a9291e6752 1116 Gene3D G3DSA:3.40.50.300 60 587 0.15 T 28-03-2018 CU254_RS29970 8f418e90fb7a314646a124a9291e6752 1116 Gene3D G3DSA:3.40.50.300 920 1105 5.0E-24 T 28-03-2018 CU254_RS29970 8f418e90fb7a314646a124a9291e6752 1116 Pfam PF13482 RNase_H superfamily 299 482 5.8E-20 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS29970 8f418e90fb7a314646a124a9291e6752 1116 SUPERFAMILY SSF53098 322 483 1.52E-5 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS29970 8f418e90fb7a314646a124a9291e6752 1116 Pfam PF13604 AAA domain 740 891 1.6E-12 T 28-03-2018 CU254_RS29970 8f418e90fb7a314646a124a9291e6752 1116 SMART SM00382 738 1074 1.6E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS29970 8f418e90fb7a314646a124a9291e6752 1116 SUPERFAMILY SSF52540 825 1092 8.56E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS29970 8f418e90fb7a314646a124a9291e6752 1116 SUPERFAMILY SSF52540 733 791 8.56E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS29970 8f418e90fb7a314646a124a9291e6752 1116 Gene3D G3DSA:3.40.50.300 684 903 7.2E-21 T 28-03-2018 CU254_RS29970 8f418e90fb7a314646a124a9291e6752 1116 Pfam PF12705 PD-(D/E)XK nuclease superfamily 78 207 1.5E-4 T 28-03-2018 CU254_RS29970 8f418e90fb7a314646a124a9291e6752 1116 Pfam PF13087 AAA domain 917 1085 2.6E-19 T 28-03-2018 CU254_RS00345 a5e3f081c11f26ba23cb5e0548edd319 132 SUPERFAMILY SSF52091 17 121 4.51E-16 T 28-03-2018 IPR002645 STAS domain CU254_RS00345 a5e3f081c11f26ba23cb5e0548edd319 132 Gene3D G3DSA:3.30.750.24 19 126 9.2E-15 T 28-03-2018 IPR002645 STAS domain CU254_RS00345 a5e3f081c11f26ba23cb5e0548edd319 132 Pfam PF13466 STAS domain 27 107 1.5E-10 T 28-03-2018 IPR002645 STAS domain CU254_RS40685 9f8fc50ea83e9cf292b16f89821d783c 413 Gene3D G3DSA:1.10.630.10 3 406 1.3E-57 T 28-03-2018 CU254_RS40685 9f8fc50ea83e9cf292b16f89821d783c 413 PRINTS PR00359 B-class P450 signature 354 365 2.9E-33 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS40685 9f8fc50ea83e9cf292b16f89821d783c 413 PRINTS PR00359 B-class P450 signature 88 99 2.9E-33 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS40685 9f8fc50ea83e9cf292b16f89821d783c 413 PRINTS PR00359 B-class P450 signature 134 150 2.9E-33 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS40685 9f8fc50ea83e9cf292b16f89821d783c 413 PRINTS PR00359 B-class P450 signature 279 290 2.9E-33 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS40685 9f8fc50ea83e9cf292b16f89821d783c 413 PRINTS PR00359 B-class P450 signature 324 339 2.9E-33 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS40685 9f8fc50ea83e9cf292b16f89821d783c 413 PRINTS PR00359 B-class P450 signature 345 354 2.9E-33 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS40685 9f8fc50ea83e9cf292b16f89821d783c 413 PRINTS PR00359 B-class P450 signature 199 221 2.9E-33 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS40685 9f8fc50ea83e9cf292b16f89821d783c 413 PRINTS PR00359 B-class P450 signature 151 166 2.9E-33 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS40685 9f8fc50ea83e9cf292b16f89821d783c 413 PRINTS PR00359 B-class P450 signature 296 323 2.9E-33 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS40685 9f8fc50ea83e9cf292b16f89821d783c 413 Pfam PF00067 Cytochrome P450 212 369 1.9E-16 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS40685 9f8fc50ea83e9cf292b16f89821d783c 413 SUPERFAMILY SSF48264 18 405 1.96E-70 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS23800 e808b3f345e1a4045f3669f6d293647e 418 SUPERFAMILY SSF51679 1 418 1.83E-93 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS23800 e808b3f345e1a4045f3669f6d293647e 418 Pfam PF00296 Luciferase-like monooxygenase 27 368 1.2E-49 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS23800 e808b3f345e1a4045f3669f6d293647e 418 PIRSF PIRSF000337 173 418 9.1E-61 T 28-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 CU254_RS23800 e808b3f345e1a4045f3669f6d293647e 418 PIRSF PIRSF000337 2 178 1.1E-48 T 28-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 CU254_RS23800 e808b3f345e1a4045f3669f6d293647e 418 Gene3D G3DSA:3.20.20.30 1 418 3.3E-85 T 28-03-2018 CU254_RS15655 8d6768b2e9f1a465d2cc691fee1c7214 190 ProSitePatterns PS01081 TetR-type HTH domain signature. 29 60 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CU254_RS15655 8d6768b2e9f1a465d2cc691fee1c7214 190 Gene3D G3DSA:1.10.357.10 61 186 5.3E-21 T 28-03-2018 CU254_RS15655 8d6768b2e9f1a465d2cc691fee1c7214 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 62 1.5E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS15655 8d6768b2e9f1a465d2cc691fee1c7214 190 Gene3D G3DSA:1.10.10.60 3 60 1.3E-20 T 28-03-2018 CU254_RS15655 8d6768b2e9f1a465d2cc691fee1c7214 190 SUPERFAMILY SSF48498 84 185 4.4E-12 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS15655 8d6768b2e9f1a465d2cc691fee1c7214 190 SUPERFAMILY SSF46689 7 88 4.54E-19 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS15655 8d6768b2e9f1a465d2cc691fee1c7214 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 1.8E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS15655 8d6768b2e9f1a465d2cc691fee1c7214 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 1.8E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS33485 23bc57e27899d48ddaf5f3416ab2bd72 200 Pfam PF00072 Response regulator receiver domain 4 115 3.5E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS33485 23bc57e27899d48ddaf5f3416ab2bd72 200 SMART SM00421 137 194 5.7E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS33485 23bc57e27899d48ddaf5f3416ab2bd72 200 Pfam PF00196 Bacterial regulatory proteins, luxR family 139 194 1.3E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS33485 23bc57e27899d48ddaf5f3416ab2bd72 200 Gene3D G3DSA:3.40.50.2300 1 137 3.6E-30 T 28-03-2018 CU254_RS33485 23bc57e27899d48ddaf5f3416ab2bd72 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 140 154 2.3E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS33485 23bc57e27899d48ddaf5f3416ab2bd72 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 182 2.3E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS33485 23bc57e27899d48ddaf5f3416ab2bd72 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 170 2.3E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS33485 23bc57e27899d48ddaf5f3416ab2bd72 200 SMART SM00448 2 115 1.6E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS33485 23bc57e27899d48ddaf5f3416ab2bd72 200 SUPERFAMILY SSF46894 131 200 7.82E-18 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS33485 23bc57e27899d48ddaf5f3416ab2bd72 200 SUPERFAMILY SSF52172 1 129 5.83E-29 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS33485 23bc57e27899d48ddaf5f3416ab2bd72 200 ProSitePatterns PS00622 LuxR-type HTH domain signature. 154 181 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS33485 23bc57e27899d48ddaf5f3416ab2bd72 200 Gene3D G3DSA:1.10.10.10 138 200 6.0E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS35005 576cfced82c12af21eef6950a3f013f9 207 SMART SM00448 2 115 1.4E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS35005 576cfced82c12af21eef6950a3f013f9 207 Pfam PF00072 Response regulator receiver domain 4 115 9.6E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS35005 576cfced82c12af21eef6950a3f013f9 207 SUPERFAMILY SSF46894 130 206 3.3E-21 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS35005 576cfced82c12af21eef6950a3f013f9 207 Pfam PF00196 Bacterial regulatory proteins, luxR family 145 199 2.4E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS35005 576cfced82c12af21eef6950a3f013f9 207 SUPERFAMILY SSF52172 2 133 8.11E-35 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS35005 576cfced82c12af21eef6950a3f013f9 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 146 160 2.5E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS35005 576cfced82c12af21eef6950a3f013f9 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 176 2.5E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS35005 576cfced82c12af21eef6950a3f013f9 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 188 2.5E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS35005 576cfced82c12af21eef6950a3f013f9 207 Gene3D G3DSA:3.40.50.2300 1 126 2.1E-36 T 28-03-2018 CU254_RS35005 576cfced82c12af21eef6950a3f013f9 207 ProSitePatterns PS00622 LuxR-type HTH domain signature. 160 187 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS35005 576cfced82c12af21eef6950a3f013f9 207 SMART SM00421 143 200 1.4E-23 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS35005 576cfced82c12af21eef6950a3f013f9 207 Gene3D G3DSA:1.10.10.10 127 207 1.8E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS00035 2f3807c5b046346745c3b66db22d3c0e 652 Pfam PF13515 Fusaric acid resistance protein-like 350 471 2.1E-20 T 28-03-2018 CU254_RS29590 08302a546e06b0db9b7ff90defff1657 314 SUPERFAMILY SSF46689 261 313 1.52E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS29590 08302a546e06b0db9b7ff90defff1657 314 Pfam PF12833 Helix-turn-helix domain 232 313 2.5E-23 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS29590 08302a546e06b0db9b7ff90defff1657 314 Gene3D G3DSA:2.60.120.280 13 214 4.0E-7 T 28-03-2018 CU254_RS29590 08302a546e06b0db9b7ff90defff1657 314 Pfam PF14525 AraC-binding-like domain 19 193 1.4E-33 T 28-03-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like CU254_RS29590 08302a546e06b0db9b7ff90defff1657 314 Gene3D G3DSA:1.10.10.60 215 260 8.6E-10 T 28-03-2018 CU254_RS29590 08302a546e06b0db9b7ff90defff1657 314 Gene3D G3DSA:1.10.10.60 261 313 4.9E-13 T 28-03-2018 CU254_RS29590 08302a546e06b0db9b7ff90defff1657 314 SUPERFAMILY SSF51182 77 130 8.36E-5 T 28-03-2018 IPR011051 RmlC-like cupin domain CU254_RS29590 08302a546e06b0db9b7ff90defff1657 314 SMART SM00342 226 311 1.6E-27 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS20815 5ce2c4376a28f338272767804871d92e 377 Pfam PF00356 Bacterial regulatory proteins, lacI family 47 92 4.3E-17 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CU254_RS20815 5ce2c4376a28f338272767804871d92e 377 SUPERFAMILY SSF47413 45 103 6.29E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS20815 5ce2c4376a28f338272767804871d92e 377 SMART SM00354 45 116 8.2E-24 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CU254_RS20815 5ce2c4376a28f338272767804871d92e 377 Pfam PF13377 Periplasmic binding protein-like domain 214 373 1.8E-24 T 28-03-2018 CU254_RS20815 5ce2c4376a28f338272767804871d92e 377 ProSitePatterns PS00356 LacI-type HTH domain signature. 48 66 - T 28-03-2018 CU254_RS20815 5ce2c4376a28f338272767804871d92e 377 Gene3D G3DSA:3.40.50.2300 98 214 8.0E-12 T 28-03-2018 CU254_RS20815 5ce2c4376a28f338272767804871d92e 377 Gene3D G3DSA:1.10.260.40 58 97 1.6E-25 T 28-03-2018 CU254_RS20815 5ce2c4376a28f338272767804871d92e 377 Gene3D G3DSA:3.40.50.2300 215 376 8.7E-28 T 28-03-2018 CU254_RS20815 5ce2c4376a28f338272767804871d92e 377 SUPERFAMILY SSF53822 155 374 1.13E-29 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CU254_RS20815 5ce2c4376a28f338272767804871d92e 377 Gene3D G3DSA:1.10.10.10 16 57 9.5E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS02365 4a96ab76e84cc7b8664377cb812fd937 638 SUPERFAMILY SSF53955 27 83 2.3E-5 T 28-03-2018 IPR023346 Lysozyme-like domain CU254_RS02365 4a96ab76e84cc7b8664377cb812fd937 638 Gene3D G3DSA:3.40.80.10 250 423 4.9E-34 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CU254_RS02365 4a96ab76e84cc7b8664377cb812fd937 638 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 276 404 9.6E-27 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CU254_RS02365 4a96ab76e84cc7b8664377cb812fd937 638 SUPERFAMILY SSF55846 266 418 5.23E-36 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CU254_RS02365 4a96ab76e84cc7b8664377cb812fd937 638 Gene3D G3DSA:1.10.530.10 13 220 9.5E-20 T 28-03-2018 CU254_RS02365 4a96ab76e84cc7b8664377cb812fd937 638 SMART SM00644 267 403 2.0E-42 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CU254_RS09005 08acac993d3617f8361f30418cf47512 297 SUPERFAMILY SSF51690 128 296 1.02E-57 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CU254_RS09005 08acac993d3617f8361f30418cf47512 297 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 128 295 3.5E-57 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CU254_RS09005 08acac993d3617f8361f30418cf47512 297 SUPERFAMILY SSF54675 21 127 7.46E-27 T 28-03-2018 CU254_RS09005 08acac993d3617f8361f30418cf47512 297 Gene3D G3DSA:3.90.1170.20 7 153 2.5E-42 T 28-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 CU254_RS09005 08acac993d3617f8361f30418cf47512 297 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 27 295 1.6E-89 T 28-03-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 CU254_RS09005 08acac993d3617f8361f30418cf47512 297 PIRSF PIRSF006250 19 297 1.4E-95 T 28-03-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 CU254_RS09005 08acac993d3617f8361f30418cf47512 297 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 39 126 2.7E-20 T 28-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 CU254_RS09005 08acac993d3617f8361f30418cf47512 297 Gene3D G3DSA:3.20.20.70 154 286 3.0E-41 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS31570 2c6a85bafea691c6362ea1038816e4a7 306 SUPERFAMILY SSF53850 100 294 5.22E-40 T 28-03-2018 CU254_RS31570 2c6a85bafea691c6362ea1038816e4a7 306 Pfam PF03466 LysR substrate binding domain 99 288 1.3E-44 T 28-03-2018 IPR005119 LysR, substrate-binding CU254_RS31570 2c6a85bafea691c6362ea1038816e4a7 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 61 2.1E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS31570 2c6a85bafea691c6362ea1038816e4a7 306 Gene3D G3DSA:1.10.10.10 1 83 1.3E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS31570 2c6a85bafea691c6362ea1038816e4a7 306 Gene3D G3DSA:3.40.190.10 177 263 1.7E-22 T 28-03-2018 CU254_RS31570 2c6a85bafea691c6362ea1038816e4a7 306 Gene3D G3DSA:3.40.190.10 90 176 5.7E-24 T 28-03-2018 CU254_RS31570 2c6a85bafea691c6362ea1038816e4a7 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.8E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS31570 2c6a85bafea691c6362ea1038816e4a7 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.8E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS31570 2c6a85bafea691c6362ea1038816e4a7 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.8E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS31570 2c6a85bafea691c6362ea1038816e4a7 306 SUPERFAMILY SSF46785 1 85 8.16E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS18130 5641fab816ec07d556b10e6e760e70b9 276 SUPERFAMILY SSF56300 5 127 2.89E-26 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CU254_RS18130 5641fab816ec07d556b10e6e760e70b9 276 SUPERFAMILY SSF56300 171 254 2.89E-26 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CU254_RS18130 5641fab816ec07d556b10e6e760e70b9 276 Gene3D G3DSA:3.60.21.10 3 273 5.3E-23 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CU254_RS18130 5641fab816ec07d556b10e6e760e70b9 276 Pfam PF00149 Calcineurin-like phosphoesterase 6 239 1.1E-14 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CU254_RS18465 26d81139869326f7d09dedacf2fc6ea9 369 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 33 134 6.9E-17 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CU254_RS18465 26d81139869326f7d09dedacf2fc6ea9 369 SUPERFAMILY SSF50129 8 192 3.14E-29 T 28-03-2018 IPR011032 GroES-like CU254_RS18465 26d81139869326f7d09dedacf2fc6ea9 369 Gene3D G3DSA:3.90.180.10 1 186 3.3E-33 T 28-03-2018 CU254_RS18465 26d81139869326f7d09dedacf2fc6ea9 369 Pfam PF00107 Zinc-binding dehydrogenase 195 324 9.7E-26 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CU254_RS18465 26d81139869326f7d09dedacf2fc6ea9 369 SUPERFAMILY SSF51735 157 326 4.99E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS18465 26d81139869326f7d09dedacf2fc6ea9 369 Gene3D G3DSA:3.40.50.720 187 310 1.2E-22 T 28-03-2018 CU254_RS21600 b8bfd4f9a8297710ab611c24873aad89 530 Gene3D G3DSA:1.10.390.10 342 512 2.7E-30 T 28-03-2018 CU254_RS21600 b8bfd4f9a8297710ab611c24873aad89 530 Pfam PF01447 Thermolysin metallopeptidase, catalytic domain 211 335 3.8E-22 T 28-03-2018 IPR013856 Peptidase M4 domain GO:0004222 CU254_RS21600 b8bfd4f9a8297710ab611c24873aad89 530 Gene3D G3DSA:3.10.450.40 126 193 0.0033 T 28-03-2018 CU254_RS21600 b8bfd4f9a8297710ab611c24873aad89 530 Pfam PF03413 Peptidase propeptide and YPEB domain 125 189 6.3E-5 T 28-03-2018 IPR025711 PepSY domain CU254_RS21600 b8bfd4f9a8297710ab611c24873aad89 530 SUPERFAMILY SSF55486 194 507 1.12E-47 T 28-03-2018 CU254_RS21600 b8bfd4f9a8297710ab611c24873aad89 530 Gene3D G3DSA:3.10.170.10 196 341 5.8E-28 T 28-03-2018 CU254_RS21600 b8bfd4f9a8297710ab611c24873aad89 530 Pfam PF02868 Thermolysin metallopeptidase, alpha-helical domain 348 507 2.8E-27 T 28-03-2018 IPR001570 Peptidase M4, C-terminal GO:0004222 CU254_RS21600 b8bfd4f9a8297710ab611c24873aad89 530 Pfam PF07504 Fungalysin/Thermolysin Propeptide Motif 65 108 2.5E-10 T 28-03-2018 IPR011096 FTP domain CU254_RS39675 2dbc77ca6beb2bae055e64e5977cdc3e 314 SUPERFAMILY SSF53271 69 304 3.92E-45 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CU254_RS39675 2dbc77ca6beb2bae055e64e5977cdc3e 314 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 5 120 5.3E-37 T 28-03-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CU254_RS39675 2dbc77ca6beb2bae055e64e5977cdc3e 314 SMART SM01400 4 120 1.4E-57 T 28-03-2018 CU254_RS39675 2dbc77ca6beb2bae055e64e5977cdc3e 314 Gene3D G3DSA:3.40.50.2020 4 141 1.3E-48 T 28-03-2018 CU254_RS39675 2dbc77ca6beb2bae055e64e5977cdc3e 314 Gene3D G3DSA:3.40.50.2020 142 313 4.6E-36 T 28-03-2018 CU254_RS39675 2dbc77ca6beb2bae055e64e5977cdc3e 314 Pfam PF14572 Phosphoribosyl synthetase-associated domain 204 311 1.8E-19 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CU254_RS39675 2dbc77ca6beb2bae055e64e5977cdc3e 314 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 5 312 4.6E-94 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CU254_RS36855 8a9003c24b2ed752b767f799438863da 247 Gene3D G3DSA:3.40.50.150 1 231 1.4E-34 T 28-03-2018 CU254_RS36855 8a9003c24b2ed752b767f799438863da 247 Pfam PF08241 Methyltransferase domain 40 126 3.5E-21 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CU254_RS36855 8a9003c24b2ed752b767f799438863da 247 SUPERFAMILY SSF53335 14 186 1.17E-35 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS38775 eb97ab3e469d9499d052035a9ccd2b81 403 SUPERFAMILY SSF55874 264 399 1.05E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS38775 eb97ab3e469d9499d052035a9ccd2b81 403 Gene3D G3DSA:3.30.565.10 200 400 7.7E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS38775 eb97ab3e469d9499d052035a9ccd2b81 403 Pfam PF07730 Histidine kinase 173 237 7.1E-18 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CU254_RS15200 90fac8f8f0501d5072784a2130270216 403 Gene3D G3DSA:1.20.1250.20 1 192 3.6E-21 T 28-03-2018 CU254_RS15200 90fac8f8f0501d5072784a2130270216 403 ProSitePatterns PS00217 Sugar transport proteins signature 2. 96 121 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CU254_RS15200 90fac8f8f0501d5072784a2130270216 403 SUPERFAMILY SSF103473 9 392 3.79E-54 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS15200 90fac8f8f0501d5072784a2130270216 403 Pfam PF00083 Sugar (and other) transporter 25 198 9.7E-21 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CU254_RS15200 90fac8f8f0501d5072784a2130270216 403 Pfam PF07690 Major Facilitator Superfamily 224 390 3.3E-9 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS15200 90fac8f8f0501d5072784a2130270216 403 Gene3D G3DSA:1.20.1250.20 193 402 3.5E-22 T 28-03-2018 CU254_RS38385 6b5d6c0301ffdaede089f48218b5ee54 398 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 148 163 1.1E-19 T 28-03-2018 CU254_RS38385 6b5d6c0301ffdaede089f48218b5ee54 398 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 1.1E-19 T 28-03-2018 CU254_RS38385 6b5d6c0301ffdaede089f48218b5ee54 398 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 284 299 1.1E-19 T 28-03-2018 CU254_RS38385 6b5d6c0301ffdaede089f48218b5ee54 398 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 299 315 1.1E-19 T 28-03-2018 CU254_RS38385 6b5d6c0301ffdaede089f48218b5ee54 398 Gene3D G3DSA:3.50.50.60 2 355 6.3E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS38385 6b5d6c0301ffdaede089f48218b5ee54 398 SUPERFAMILY SSF51905 3 169 1.3E-58 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS38385 6b5d6c0301ffdaede089f48218b5ee54 398 SUPERFAMILY SSF51905 271 357 1.3E-58 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS38385 6b5d6c0301ffdaede089f48218b5ee54 398 Pfam PF01494 FAD binding domain 3 167 2.1E-12 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CU254_RS38385 6b5d6c0301ffdaede089f48218b5ee54 398 Pfam PF01494 FAD binding domain 281 345 2.5E-11 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CU254_RS17990 563066b15747e53b5fef4cca666d6f0d 448 Gene3D G3DSA:1.10.287.620 36 135 3.5E-4 T 28-03-2018 CU254_RS17990 563066b15747e53b5fef4cca666d6f0d 448 Pfam PF00877 NlpC/P60 family 324 434 2.8E-22 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CU254_RS17990 563066b15747e53b5fef4cca666d6f0d 448 SUPERFAMILY SSF54001 307 445 8.83E-29 T 28-03-2018 CU254_RS17990 563066b15747e53b5fef4cca666d6f0d 448 Gene3D G3DSA:3.90.1720.10 303 447 2.6E-28 T 28-03-2018 CU254_RS24460 f1c633c055b8192474da40c19b828167 1053 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 26 658 7.0E-177 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CU254_RS24460 f1c633c055b8192474da40c19b828167 1053 SUPERFAMILY SSF50677 216 395 5.44E-47 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CU254_RS24460 f1c633c055b8192474da40c19b828167 1053 Gene3D G3DSA:3.90.740.10 216 508 2.2E-88 T 28-03-2018 CU254_RS24460 f1c633c055b8192474da40c19b828167 1053 SUPERFAMILY SSF47323 679 907 2.8E-45 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CU254_RS24460 f1c633c055b8192474da40c19b828167 1053 SUPERFAMILY SSF52374 416 657 4.22E-124 T 28-03-2018 CU254_RS24460 f1c633c055b8192474da40c19b828167 1053 SUPERFAMILY SSF52374 10 210 4.22E-124 T 28-03-2018 CU254_RS24460 f1c633c055b8192474da40c19b828167 1053 Pfam PF08264 Anticodon-binding domain of tRNA 709 846 3.3E-24 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CU254_RS24460 f1c633c055b8192474da40c19b828167 1053 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 11 1047 13.907 T 28-03-2018 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CU254_RS24460 f1c633c055b8192474da40c19b828167 1053 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 60 71 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CU254_RS24460 f1c633c055b8192474da40c19b828167 1053 Gene3D G3DSA:3.40.50.620 43 211 7.7E-36 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS24460 f1c633c055b8192474da40c19b828167 1053 Gene3D G3DSA:1.10.730.10 609 842 8.6E-50 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CU254_RS24460 f1c633c055b8192474da40c19b828167 1053 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 583 592 6.6E-32 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CU254_RS24460 f1c633c055b8192474da40c19b828167 1053 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 414 429 6.6E-32 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CU254_RS24460 f1c633c055b8192474da40c19b828167 1053 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 240 263 6.6E-32 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CU254_RS24460 f1c633c055b8192474da40c19b828167 1053 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 543 556 6.6E-32 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CU254_RS24460 f1c633c055b8192474da40c19b828167 1053 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 53 64 6.6E-32 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CU254_RS24460 f1c633c055b8192474da40c19b828167 1053 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 13 857 2.6E-252 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CU254_RS14115 8d761844677ce3bc8460e2988037fd31 195 Gene3D G3DSA:1.10.357.10 72 190 7.1E-17 T 28-03-2018 CU254_RS14115 8d761844677ce3bc8460e2988037fd31 195 SUPERFAMILY SSF46689 5 64 2.79E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS14115 8d761844677ce3bc8460e2988037fd31 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 62 1.3E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS14115 8d761844677ce3bc8460e2988037fd31 195 Gene3D G3DSA:1.10.10.60 3 71 7.6E-17 T 28-03-2018 CU254_RS38750 6d3cff29e2b74431fd044b31e62d2b65 127 SUPERFAMILY SSF51064 68 123 6.15E-8 T 28-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 CU254_RS38750 6d3cff29e2b74431fd044b31e62d2b65 127 Gene3D G3DSA:2.30.22.10 66 123 1.7E-11 T 28-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 CU254_RS38750 6d3cff29e2b74431fd044b31e62d2b65 127 PRINTS PR00773 GrpE protein signature 102 121 2.7E-5 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CU254_RS38750 6d3cff29e2b74431fd044b31e62d2b65 127 PRINTS PR00773 GrpE protein signature 74 89 2.7E-5 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CU254_RS38750 6d3cff29e2b74431fd044b31e62d2b65 127 PRINTS PR00773 GrpE protein signature 17 32 2.7E-5 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CU254_RS38750 6d3cff29e2b74431fd044b31e62d2b65 127 Pfam PF01025 GrpE 55 121 1.4E-8 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CU254_RS13525 59c380f4a0e437bdd5eaf73cbcf07296 434 SUPERFAMILY SSF88659 132 189 9.91E-10 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS13525 59c380f4a0e437bdd5eaf73cbcf07296 434 Gene3D G3DSA:1.10.10.10 109 192 2.4E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS13525 59c380f4a0e437bdd5eaf73cbcf07296 434 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 38 190 1.4E-12 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS13525 59c380f4a0e437bdd5eaf73cbcf07296 434 Pfam PF08281 Sigma-70, region 4 140 189 5.7E-9 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS13525 59c380f4a0e437bdd5eaf73cbcf07296 434 SUPERFAMILY SSF88946 37 105 6.67E-11 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS13525 59c380f4a0e437bdd5eaf73cbcf07296 434 Gene3D G3DSA:1.10.1740.10 26 108 3.7E-13 T 28-03-2018 CU254_RS13525 59c380f4a0e437bdd5eaf73cbcf07296 434 Pfam PF04542 Sigma-70 region 2 42 107 4.7E-6 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS34830 f756fd879531bc29288ebde221bbc40f 381 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 230 378 2.1E-47 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS34830 f756fd879531bc29288ebde221bbc40f 381 Gene3D G3DSA:1.20.140.10 222 380 1.0E-57 T 28-03-2018 CU254_RS34830 f756fd879531bc29288ebde221bbc40f 381 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 124 217 2.3E-25 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CU254_RS34830 f756fd879531bc29288ebde221bbc40f 381 SUPERFAMILY SSF47203 229 379 1.77E-54 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS34830 f756fd879531bc29288ebde221bbc40f 381 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 126 138 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CU254_RS34830 f756fd879531bc29288ebde221bbc40f 381 SUPERFAMILY SSF56645 7 242 7.59E-72 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS34830 f756fd879531bc29288ebde221bbc40f 381 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 119 1.8E-26 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS34830 f756fd879531bc29288ebde221bbc40f 381 Gene3D G3DSA:1.10.540.10 5 124 2.2E-29 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS34830 f756fd879531bc29288ebde221bbc40f 381 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 337 356 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CU254_RS34830 f756fd879531bc29288ebde221bbc40f 381 PIRSF PIRSF016578 2 380 3.3E-23 T 28-03-2018 CU254_RS34830 f756fd879531bc29288ebde221bbc40f 381 Gene3D G3DSA:2.40.110.10 125 221 6.3E-36 T 28-03-2018 CU254_RS02140 fe11d501d966776001d78aafdff7d7a1 542 Pfam PF05108 Type VII secretion system ESX-1, transport TM domain B 4 521 2.1E-120 T 28-03-2018 IPR007795 Type VII secretion system EccB CU254_RS02140 fe11d501d966776001d78aafdff7d7a1 542 TIGRFAM TIGR03919 T7SS_EccB: type VII secretion protein EccB 131 508 1.0E-61 T 28-03-2018 IPR007795 Type VII secretion system EccB CU254_RS01605 e613b5145b43b74302cf232b349001c9 320 Gene3D G3DSA:2.130.10.10 218 318 5.6E-10 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CU254_RS01605 e613b5145b43b74302cf232b349001c9 320 Gene3D G3DSA:2.130.10.10 25 94 5.0E-8 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CU254_RS01605 e613b5145b43b74302cf232b349001c9 320 SUPERFAMILY SSF50969 46 317 8.63E-30 T 28-03-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like CU254_RS01605 e613b5145b43b74302cf232b349001c9 320 Gene3D G3DSA:2.130.10.10 95 217 8.1E-19 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CU254_RS07090 0b48c11d11336f8ad9037fa6a907f4b1 224 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 23 164 3.0E-43 T 28-03-2018 IPR024747 Pyridoxamine 5'-phosphate oxidase-related CU254_RS07090 0b48c11d11336f8ad9037fa6a907f4b1 224 Gene3D G3DSA:2.30.110.10 21 213 1.4E-42 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS07090 0b48c11d11336f8ad9037fa6a907f4b1 224 SUPERFAMILY SSF50475 4 187 2.89E-53 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS09915 9248b60c56f81ec14299aa333823dfe2 293 Gene3D G3DSA:3.40.50.720 1 291 1.5E-66 T 28-03-2018 CU254_RS09915 9248b60c56f81ec14299aa333823dfe2 293 SUPERFAMILY SSF51735 1 244 2.91E-68 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS09915 9248b60c56f81ec14299aa333823dfe2 293 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS09915 9248b60c56f81ec14299aa333823dfe2 293 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 1.4E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS09915 9248b60c56f81ec14299aa333823dfe2 293 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 1.4E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS09915 9248b60c56f81ec14299aa333823dfe2 293 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 1.4E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS09915 9248b60c56f81ec14299aa333823dfe2 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.1E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS09915 9248b60c56f81ec14299aa333823dfe2 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 1.1E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS09915 9248b60c56f81ec14299aa333823dfe2 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 1.1E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS09915 9248b60c56f81ec14299aa333823dfe2 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 1.1E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS09915 9248b60c56f81ec14299aa333823dfe2 293 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 1.1E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS09915 9248b60c56f81ec14299aa333823dfe2 293 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 242 3.6E-46 T 28-03-2018 CU254_RS09915 9248b60c56f81ec14299aa333823dfe2 293 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 216 2.1E-4 T 28-03-2018 CU254_RS26600 61d99fdb783a73c67f014c9370f70e59 231 PIRSF PIRSF000857 3 231 3.2E-87 T 28-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 CU254_RS26600 61d99fdb783a73c67f014c9370f70e59 231 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 41 206 4.1E-38 T 28-03-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 CU254_RS26600 61d99fdb783a73c67f014c9370f70e59 231 Gene3D G3DSA:3.40.50.620 5 231 1.5E-33 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS26600 61d99fdb783a73c67f014c9370f70e59 231 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 23 230 2.3E-60 T 28-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 CU254_RS26600 61d99fdb783a73c67f014c9370f70e59 231 SUPERFAMILY SSF52402 16 195 1.42E-36 T 28-03-2018 CU254_RS05105 d2deb46dd7539ec50c90f16f55e86f11 334 Gene3D G3DSA:3.40.50.2300 163 333 1.3E-49 T 28-03-2018 CU254_RS05105 d2deb46dd7539ec50c90f16f55e86f11 334 Gene3D G3DSA:1.10.260.40 3 58 2.3E-21 T 28-03-2018 CU254_RS05105 d2deb46dd7539ec50c90f16f55e86f11 334 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 6.1E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CU254_RS05105 d2deb46dd7539ec50c90f16f55e86f11 334 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 6.1E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CU254_RS05105 d2deb46dd7539ec50c90f16f55e86f11 334 SUPERFAMILY SSF53822 63 332 1.1E-63 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CU254_RS05105 d2deb46dd7539ec50c90f16f55e86f11 334 Gene3D G3DSA:3.40.50.2300 59 162 2.6E-21 T 28-03-2018 CU254_RS05105 d2deb46dd7539ec50c90f16f55e86f11 334 SUPERFAMILY SSF47413 3 60 2.04E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS05105 d2deb46dd7539ec50c90f16f55e86f11 334 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 8.0E-15 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CU254_RS05105 d2deb46dd7539ec50c90f16f55e86f11 334 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 28-03-2018 CU254_RS05105 d2deb46dd7539ec50c90f16f55e86f11 334 SMART SM00354 2 72 6.7E-21 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CU254_RS05105 d2deb46dd7539ec50c90f16f55e86f11 334 Pfam PF13377 Periplasmic binding protein-like domain 168 331 3.7E-39 T 28-03-2018 CU254_RS20560 bb7c6ad0363bddbfa9159031ec65107b 598 Pfam PF01019 Gamma-glutamyltranspeptidase 59 587 1.5E-147 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CU254_RS20560 bb7c6ad0363bddbfa9159031ec65107b 598 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 493 510 1.7E-62 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CU254_RS20560 bb7c6ad0363bddbfa9159031ec65107b 598 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 142 160 1.7E-62 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CU254_RS20560 bb7c6ad0363bddbfa9159031ec65107b 598 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 160 179 1.7E-62 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CU254_RS20560 bb7c6ad0363bddbfa9159031ec65107b 598 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 66 91 1.7E-62 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CU254_RS20560 bb7c6ad0363bddbfa9159031ec65107b 598 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 268 284 1.7E-62 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CU254_RS20560 bb7c6ad0363bddbfa9159031ec65107b 598 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 298 317 1.7E-62 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CU254_RS20560 bb7c6ad0363bddbfa9159031ec65107b 598 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 433 451 1.7E-62 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CU254_RS20560 bb7c6ad0363bddbfa9159031ec65107b 598 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 469 484 1.7E-62 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CU254_RS20560 bb7c6ad0363bddbfa9159031ec65107b 598 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 409 427 1.7E-62 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CU254_RS20560 bb7c6ad0363bddbfa9159031ec65107b 598 SUPERFAMILY SSF56235 37 588 3.47E-148 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CU254_RS20560 bb7c6ad0363bddbfa9159031ec65107b 598 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 46 582 4.8E-122 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CU254_RS14305 9ee1af0ab212219c28353ebb6319728f 116 PIRSF PIRSF016821 1 116 4.0E-42 T 28-03-2018 IPR025708 Heat shock protein 15 GO:0003677|GO:0003727|GO:0034605|GO:0043023 CU254_RS14305 9ee1af0ab212219c28353ebb6319728f 116 Gene3D G3DSA:3.10.290.10 1 95 3.5E-16 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CU254_RS14305 9ee1af0ab212219c28353ebb6319728f 116 Pfam PF01479 S4 domain 1 45 3.1E-8 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CU254_RS14305 9ee1af0ab212219c28353ebb6319728f 116 SUPERFAMILY SSF55174 1 80 4.84E-19 T 28-03-2018 CU254_RS11150 5913d89ca17ccf565d8cbe7082f4a11f 331 Pfam PF00296 Luciferase-like monooxygenase 17 299 2.3E-44 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS11150 5913d89ca17ccf565d8cbe7082f4a11f 331 SUPERFAMILY SSF51679 6 323 2.75E-67 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS11150 5913d89ca17ccf565d8cbe7082f4a11f 331 Gene3D G3DSA:3.20.20.30 3 327 1.3E-70 T 28-03-2018 CU254_RS11150 5913d89ca17ccf565d8cbe7082f4a11f 331 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 7 322 3.5E-103 T 28-03-2018 IPR019949 Luciferase family oxidoreductase, group 1 CU254_RS31640 eae682a76995b4a0cebcec340f0d8321 153 SUPERFAMILY SSF55729 1 150 5.66E-25 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS31640 eae682a76995b4a0cebcec340f0d8321 153 Gene3D G3DSA:3.40.630.30 2 153 7.8E-27 T 28-03-2018 CU254_RS31640 eae682a76995b4a0cebcec340f0d8321 153 Pfam PF00583 Acetyltransferase (GNAT) family 33 131 2.9E-14 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS23050 f1e6d3e03eee6fc8b9235288dc110c44 387 Pfam PF00232 Glycosyl hydrolase family 1 20 386 5.3E-94 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CU254_RS23050 f1e6d3e03eee6fc8b9235288dc110c44 387 Gene3D G3DSA:3.20.20.80 19 387 2.6E-111 T 28-03-2018 CU254_RS23050 f1e6d3e03eee6fc8b9235288dc110c44 387 PRINTS PR00131 Glycosyl hydrolase family 1 signature 319 330 8.2E-15 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CU254_RS23050 f1e6d3e03eee6fc8b9235288dc110c44 387 PRINTS PR00131 Glycosyl hydrolase family 1 signature 340 357 8.2E-15 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CU254_RS23050 f1e6d3e03eee6fc8b9235288dc110c44 387 PRINTS PR00131 Glycosyl hydrolase family 1 signature 298 306 8.2E-15 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CU254_RS23050 f1e6d3e03eee6fc8b9235288dc110c44 387 PRINTS PR00131 Glycosyl hydrolase family 1 signature 233 247 8.2E-15 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CU254_RS23050 f1e6d3e03eee6fc8b9235288dc110c44 387 SUPERFAMILY SSF51445 6 387 7.15E-120 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS17200 c1c37fb3dba3e54c66a5f31b72dd875b 302 Gene3D G3DSA:3.60.21.10 35 300 7.2E-35 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CU254_RS17200 c1c37fb3dba3e54c66a5f31b72dd875b 302 SUPERFAMILY SSF56300 45 259 6.84E-41 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CU254_RS17200 c1c37fb3dba3e54c66a5f31b72dd875b 302 Pfam PF00149 Calcineurin-like phosphoesterase 45 236 2.4E-9 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CU254_RS04035 19f136a961676f7fd251d9e073719f47 108 TIGRFAM TIGR02378 nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit 4 105 4.2E-36 T 28-03-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 CU254_RS04035 19f136a961676f7fd251d9e073719f47 108 Gene3D G3DSA:2.102.10.10 2 108 2.1E-21 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CU254_RS04035 19f136a961676f7fd251d9e073719f47 108 Pfam PF13806 Rieske-like [2Fe-2S] domain 4 105 4.4E-37 T 28-03-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 CU254_RS04035 19f136a961676f7fd251d9e073719f47 108 SUPERFAMILY SSF50022 3 107 3.74E-37 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CU254_RS11310 cecda178fdcfe778ad5bb14656d0364e 299 Gene3D G3DSA:3.30.930.10 115 218 0.15 T 28-03-2018 CU254_RS29745 08fca40c67e7b63cab6f025bcf59c0db 439 Gene3D G3DSA:1.20.5.1230 81 431 0.0087 T 28-03-2018 CU254_RS16440 402d4b4ad6481cf33a698f0bb26995a8 214 SUPERFAMILY SSF46785 11 76 9.1E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS16440 402d4b4ad6481cf33a698f0bb26995a8 214 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 32 46 1.4E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS16440 402d4b4ad6481cf33a698f0bb26995a8 214 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 62 1.4E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS16440 402d4b4ad6481cf33a698f0bb26995a8 214 Gene3D G3DSA:1.10.10.10 1 75 1.1E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS16440 402d4b4ad6481cf33a698f0bb26995a8 214 SMART SM00895 82 202 2.5E-16 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS16440 402d4b4ad6481cf33a698f0bb26995a8 214 Gene3D G3DSA:1.20.120.530 76 207 2.4E-27 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS16440 402d4b4ad6481cf33a698f0bb26995a8 214 SMART SM00345 14 72 9.4E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS16440 402d4b4ad6481cf33a698f0bb26995a8 214 SUPERFAMILY SSF48008 78 204 2.88E-24 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS16440 402d4b4ad6481cf33a698f0bb26995a8 214 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 67 3.5E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS16440 402d4b4ad6481cf33a698f0bb26995a8 214 Pfam PF07729 FCD domain 82 201 2.3E-21 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS34720 7e95eb9665bc118a858d71a1b832932b 260 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 254 5.7E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS34720 7e95eb9665bc118a858d71a1b832932b 260 Gene3D G3DSA:1.10.3720.10 1 247 2.0E-35 T 28-03-2018 CU254_RS34720 7e95eb9665bc118a858d71a1b832932b 260 SUPERFAMILY SSF161098 3 260 1.83E-59 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS39240 56a00c0114230354332dd76a14befbe7 377 PIRSF PIRSF000804 1 376 3.1E-98 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CU254_RS39240 56a00c0114230354332dd76a14befbe7 377 SMART SM00480 17 371 1.9E-122 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CU254_RS39240 56a00c0114230354332dd76a14befbe7 377 SUPERFAMILY SSF55979 132 249 2.9E-20 T 28-03-2018 CU254_RS39240 56a00c0114230354332dd76a14befbe7 377 SUPERFAMILY SSF55979 1 122 4.54E-22 T 28-03-2018 CU254_RS39240 56a00c0114230354332dd76a14befbe7 377 Pfam PF02767 DNA polymerase III beta subunit, central domain 131 247 2.1E-30 T 28-03-2018 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CU254_RS39240 56a00c0114230354332dd76a14befbe7 377 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 122 1.4E-32 T 28-03-2018 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CU254_RS39240 56a00c0114230354332dd76a14befbe7 377 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 250 359 3.7E-33 T 28-03-2018 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CU254_RS39240 56a00c0114230354332dd76a14befbe7 377 Gene3D G3DSA:3.10.150.10 126 252 4.1E-32 T 28-03-2018 CU254_RS39240 56a00c0114230354332dd76a14befbe7 377 Gene3D G3DSA:3.10.150.10 253 375 8.1E-37 T 28-03-2018 CU254_RS39240 56a00c0114230354332dd76a14befbe7 377 SUPERFAMILY SSF55979 250 375 4.19E-31 T 28-03-2018 CU254_RS39240 56a00c0114230354332dd76a14befbe7 377 Gene3D G3DSA:3.10.150.10 1 125 1.7E-31 T 28-03-2018 CU254_RS39240 56a00c0114230354332dd76a14befbe7 377 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 375 1.3E-98 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CU254_RS12970 275c68c4f07bc5613bc119515d49124f 268 SUPERFAMILY SSF53474 4 263 3.24E-54 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS12970 275c68c4f07bc5613bc119515d49124f 268 PRINTS PR00412 Epoxide hydrolase signature 239 261 6.4E-6 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS12970 275c68c4f07bc5613bc119515d49124f 268 PRINTS PR00412 Epoxide hydrolase signature 102 115 6.4E-6 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS12970 275c68c4f07bc5613bc119515d49124f 268 PRINTS PR00412 Epoxide hydrolase signature 47 62 6.4E-6 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS12970 275c68c4f07bc5613bc119515d49124f 268 Gene3D G3DSA:3.40.50.1820 2 266 4.1E-53 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS12970 275c68c4f07bc5613bc119515d49124f 268 PRINTS PR00111 Alpha/beta hydrolase fold signature 47 62 1.5E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS12970 275c68c4f07bc5613bc119515d49124f 268 PRINTS PR00111 Alpha/beta hydrolase fold signature 102 115 1.5E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS12970 275c68c4f07bc5613bc119515d49124f 268 PRINTS PR00111 Alpha/beta hydrolase fold signature 88 101 1.5E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS12970 275c68c4f07bc5613bc119515d49124f 268 Pfam PF12697 Alpha/beta hydrolase family 22 257 2.2E-20 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS26320 d9ef32b781939f05515b3e1f65befa48 357 Gene3D G3DSA:3.30.497.10 2 162 6.8E-37 T 28-03-2018 CU254_RS26320 d9ef32b781939f05515b3e1f65befa48 357 Pfam PF00079 Serpin (serine protease inhibitor) 6 356 1.3E-80 T 28-03-2018 IPR023796 Serpin domain CU254_RS26320 d9ef32b781939f05515b3e1f65befa48 357 ProSitePatterns PS00284 Serpins signature. 329 339 - T 28-03-2018 IPR023795 Serpin, conserved site CU254_RS26320 d9ef32b781939f05515b3e1f65befa48 357 Gene3D G3DSA:2.30.39.10 163 357 6.3E-52 T 28-03-2018 CU254_RS26320 d9ef32b781939f05515b3e1f65befa48 357 SUPERFAMILY SSF56574 6 356 2.62E-86 T 28-03-2018 IPR023796 Serpin domain CU254_RS26320 d9ef32b781939f05515b3e1f65befa48 357 SMART SM00093 9 356 2.4E-67 T 28-03-2018 IPR023796 Serpin domain CU254_RS06580 22923b4e9481714bf538aeacf520a9ba 208 SUPERFAMILY SSF46689 8 75 1.44E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS06580 22923b4e9481714bf538aeacf520a9ba 208 Gene3D G3DSA:1.10.260.40 42 73 2.0E-9 T 28-03-2018 CU254_RS06580 22923b4e9481714bf538aeacf520a9ba 208 ProSitePatterns PS01081 TetR-type HTH domain signature. 25 55 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CU254_RS06580 22923b4e9481714bf538aeacf520a9ba 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 9.4E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS06580 22923b4e9481714bf538aeacf520a9ba 208 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 9.4E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS06580 22923b4e9481714bf538aeacf520a9ba 208 Gene3D G3DSA:1.10.10.60 8 41 3.4E-17 T 28-03-2018 CU254_RS06580 22923b4e9481714bf538aeacf520a9ba 208 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 59 1.7E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS30980 6024a4155ad242e270dcfcbf747af2c2 316 Gene3D G3DSA:3.40.50.1100 24 135 5.7E-36 T 28-03-2018 CU254_RS30980 6024a4155ad242e270dcfcbf747af2c2 316 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 287 8.4E-65 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CU254_RS30980 6024a4155ad242e270dcfcbf747af2c2 316 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 28-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 CU254_RS30980 6024a4155ad242e270dcfcbf747af2c2 316 Gene3D G3DSA:3.40.50.1100 136 309 1.4E-37 T 28-03-2018 CU254_RS30980 6024a4155ad242e270dcfcbf747af2c2 316 TIGRFAM TIGR01136 cysKM: cysteine synthase 9 299 6.4E-107 T 28-03-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 CU254_RS30980 6024a4155ad242e270dcfcbf747af2c2 316 SUPERFAMILY SSF53686 4 296 7.6E-83 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CU254_RS14070 580faf2212cecdb62f30302b7dd5d1b9 452 Gene3D G3DSA:1.20.1250.20 16 210 3.9E-32 T 28-03-2018 CU254_RS14070 580faf2212cecdb62f30302b7dd5d1b9 452 Gene3D G3DSA:1.20.1250.20 262 452 4.1E-18 T 28-03-2018 CU254_RS14070 580faf2212cecdb62f30302b7dd5d1b9 452 ProSitePatterns PS00216 Sugar transport proteins signature 1. 77 93 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CU254_RS14070 580faf2212cecdb62f30302b7dd5d1b9 452 Pfam PF07690 Major Facilitator Superfamily 27 412 1.5E-44 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS14070 580faf2212cecdb62f30302b7dd5d1b9 452 SUPERFAMILY SSF103473 14 204 8.11E-57 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS14070 580faf2212cecdb62f30302b7dd5d1b9 452 SUPERFAMILY SSF103473 258 451 8.11E-57 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS14070 580faf2212cecdb62f30302b7dd5d1b9 452 PRINTS PR01036 Tetracycline resistance protein TetB signature 147 171 7.8E-8 T 28-03-2018 CU254_RS14070 580faf2212cecdb62f30302b7dd5d1b9 452 PRINTS PR01036 Tetracycline resistance protein TetB signature 117 137 7.8E-8 T 28-03-2018 CU254_RS14070 580faf2212cecdb62f30302b7dd5d1b9 452 PRINTS PR01036 Tetracycline resistance protein TetB signature 26 50 7.8E-8 T 28-03-2018 CU254_RS02985 7dcead5bcd72ec4448331494de5fca03 324 SMART SM01133 65 305 5.1E-70 T 28-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CU254_RS02985 7dcead5bcd72ec4448331494de5fca03 324 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 67 284 7.6E-53 T 28-03-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CU254_RS02985 7dcead5bcd72ec4448331494de5fca03 324 Gene3D G3DSA:3.20.20.70 42 324 2.5E-92 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS02985 7dcead5bcd72ec4448331494de5fca03 324 SUPERFAMILY SSF51569 64 304 1.47E-72 T 28-03-2018 CU254_RS02985 7dcead5bcd72ec4448331494de5fca03 324 PIRSF PIRSF001357 59 314 2.3E-77 T 28-03-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CU254_RS02985 7dcead5bcd72ec4448331494de5fca03 324 Pfam PF01791 DeoC/LacD family aldolase 62 302 3.4E-26 T 28-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CU254_RS13855 5b455650b6be0b17454bf15d2b7e34ab 245 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 68 2.1E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS13855 5b455650b6be0b17454bf15d2b7e34ab 245 Gene3D G3DSA:1.10.10.60 13 69 5.5E-22 T 28-03-2018 CU254_RS13855 5b455650b6be0b17454bf15d2b7e34ab 245 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 5.1E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS13855 5b455650b6be0b17454bf15d2b7e34ab 245 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 5.1E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS13855 5b455650b6be0b17454bf15d2b7e34ab 245 Gene3D G3DSA:1.10.357.10 70 204 9.2E-25 T 28-03-2018 CU254_RS13855 5b455650b6be0b17454bf15d2b7e34ab 245 ProSitePatterns PS01081 TetR-type HTH domain signature. 35 66 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CU254_RS13855 5b455650b6be0b17454bf15d2b7e34ab 245 SUPERFAMILY SSF46689 13 89 1.75E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS33445 0877967ac7b72dc683b7265d1ce764e0 468 SUPERFAMILY SSF57802 413 460 2.55E-14 T 28-03-2018 CU254_RS33445 0877967ac7b72dc683b7265d1ce764e0 468 Gene3D G3DSA:2.20.28.10 410 465 9.1E-17 T 28-03-2018 CU254_RS33445 0877967ac7b72dc683b7265d1ce764e0 468 Pfam PF00301 Rubredoxin 415 460 1.1E-15 T 28-03-2018 IPR024935 Rubredoxin domain GO:0005506 CU254_RS33445 0877967ac7b72dc683b7265d1ce764e0 468 ProSitePatterns PS00202 Rubredoxin signature. 443 453 - T 28-03-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 CU254_RS33445 0877967ac7b72dc683b7265d1ce764e0 468 Pfam PF00487 Fatty acid desaturase 123 334 1.6E-29 T 28-03-2018 IPR005804 Fatty acid desaturase domain GO:0006629 CU254_RS00455 1a4b2b6313401b3d6bc6816d358090bb 2745 Pfam PF14891 Effector protein 140 282 1.4E-6 T 28-03-2018 IPR028208 Effector protein NleD-like CU254_RS00455 1a4b2b6313401b3d6bc6816d358090bb 2745 Gene3D G3DSA:1.10.490.40 772 928 1.4E-30 T 28-03-2018 CU254_RS00455 1a4b2b6313401b3d6bc6816d358090bb 2745 Pfam PF02764 Diphtheria toxin, T domain 831 916 2.4E-6 T 28-03-2018 IPR022405 Diphtheria toxin, translocation domain CU254_RS00455 1a4b2b6313401b3d6bc6816d358090bb 2745 Gene3D G3DSA:3.90.210.10 516 744 9.6E-18 T 28-03-2018 CU254_RS00455 1a4b2b6313401b3d6bc6816d358090bb 2745 Gene3D G3DSA:2.120.10.10 1544 2662 1.4E-14 T 28-03-2018 CU254_RS00455 1a4b2b6313401b3d6bc6816d358090bb 2745 Gene3D G3DSA:3.90.1240.10 136 362 3.1E-29 T 28-03-2018 CU254_RS00455 1a4b2b6313401b3d6bc6816d358090bb 2745 Gene3D G3DSA:2.110.10.10 1183 1328 6.7E-5 T 28-03-2018 IPR000585 Hemopexin-like domain CU254_RS00455 1a4b2b6313401b3d6bc6816d358090bb 2745 SUPERFAMILY SSF50923 1118 1314 2.68E-14 T 28-03-2018 IPR000585 Hemopexin-like domain CU254_RS00455 1a4b2b6313401b3d6bc6816d358090bb 2745 PRINTS PR00769 Diphtheria toxin signature 886 909 7.2E-5 T 28-03-2018 IPR000512 Diphtheria toxin (NAD+-dipthamide ADP-ribosyltransferase) GO:0005615|GO:0047286|GO:0090729 CU254_RS00455 1a4b2b6313401b3d6bc6816d358090bb 2745 PRINTS PR00769 Diphtheria toxin signature 859 881 7.2E-5 T 28-03-2018 IPR000512 Diphtheria toxin (NAD+-dipthamide ADP-ribosyltransferase) GO:0005615|GO:0047286|GO:0090729 CU254_RS00455 1a4b2b6313401b3d6bc6816d358090bb 2745 SMART SM00120 1275 1323 100.0 T 28-03-2018 IPR018487 Hemopexin-like repeats CU254_RS00455 1a4b2b6313401b3d6bc6816d358090bb 2745 SMART SM00120 1096 1151 0.0042 T 28-03-2018 IPR018487 Hemopexin-like repeats CU254_RS00455 1a4b2b6313401b3d6bc6816d358090bb 2745 SMART SM00120 1214 1267 2.9 T 28-03-2018 IPR018487 Hemopexin-like repeats CU254_RS00455 1a4b2b6313401b3d6bc6816d358090bb 2745 SMART SM00120 1158 1208 20.0 T 28-03-2018 IPR018487 Hemopexin-like repeats CU254_RS00455 1a4b2b6313401b3d6bc6816d358090bb 2745 SUPERFAMILY SSF56845 828 916 2.48E-7 T 28-03-2018 IPR022405 Diphtheria toxin, translocation domain CU254_RS00455 1a4b2b6313401b3d6bc6816d358090bb 2745 Gene3D G3DSA:2.110.10.10 1080 1182 1.7E-10 T 28-03-2018 IPR000585 Hemopexin-like domain CU254_RS00455 1a4b2b6313401b3d6bc6816d358090bb 2745 SUPERFAMILY SSF56399 523 674 1.15E-8 T 28-03-2018 CU254_RS00455 1a4b2b6313401b3d6bc6816d358090bb 2745 SUPERFAMILY SSF50939 2231 2271 2.63E-6 T 28-03-2018 IPR011040 Sialidases KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 CU254_RS00455 1a4b2b6313401b3d6bc6816d358090bb 2745 SUPERFAMILY SSF50939 2421 2482 2.63E-6 T 28-03-2018 IPR011040 Sialidases KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 CU254_RS00455 1a4b2b6313401b3d6bc6816d358090bb 2745 SUPERFAMILY SSF50939 2603 2638 2.63E-6 T 28-03-2018 IPR011040 Sialidases KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 CU254_RS04180 35238c06eeae1ab9df62c0488564dd95 398 SUPERFAMILY SSF46785 2 66 8.98E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS04180 35238c06eeae1ab9df62c0488564dd95 398 Gene3D G3DSA:3.30.420.40 64 190 1.4E-20 T 28-03-2018 CU254_RS04180 35238c06eeae1ab9df62c0488564dd95 398 Pfam PF00480 ROK family 82 326 2.1E-25 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CU254_RS04180 35238c06eeae1ab9df62c0488564dd95 398 SUPERFAMILY SSF53067 72 369 1.24E-30 T 28-03-2018 CU254_RS04180 35238c06eeae1ab9df62c0488564dd95 398 Gene3D G3DSA:1.10.10.10 1 63 9.9E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS04180 35238c06eeae1ab9df62c0488564dd95 398 Gene3D G3DSA:3.30.420.40 191 379 5.7E-39 T 28-03-2018 CU254_RS34420 b011d1654a35cf1008a58fd89fb00604 332 Gene3D G3DSA:3.90.850.10 48 315 7.1E-60 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CU254_RS34420 b011d1654a35cf1008a58fd89fb00604 332 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 100 306 1.1E-48 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CU254_RS34420 b011d1654a35cf1008a58fd89fb00604 332 SUPERFAMILY SSF56529 87 306 1.57E-53 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CU254_RS38455 d3f5322d79cbe6b0d0b31b7fae7afe05 212 SUPERFAMILY SSF53335 24 199 4.11E-23 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS38455 d3f5322d79cbe6b0d0b31b7fae7afe05 212 Gene3D G3DSA:3.40.50.150 23 210 7.4E-21 T 28-03-2018 CU254_RS38455 d3f5322d79cbe6b0d0b31b7fae7afe05 212 Pfam PF13649 Methyltransferase domain 35 118 1.8E-11 T 28-03-2018 CU254_RS35070 1b32dce1021a07c745b896a80c23c7ac 224 PRINTS PR00088 Haem oxygenase signature 165 186 3.2E-27 T 28-03-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 CU254_RS35070 1b32dce1021a07c745b896a80c23c7ac 224 PRINTS PR00088 Haem oxygenase signature 123 144 3.2E-27 T 28-03-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 CU254_RS35070 1b32dce1021a07c745b896a80c23c7ac 224 PRINTS PR00088 Haem oxygenase signature 71 96 3.2E-27 T 28-03-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 CU254_RS35070 1b32dce1021a07c745b896a80c23c7ac 224 PRINTS PR00088 Haem oxygenase signature 197 215 3.2E-27 T 28-03-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 CU254_RS35070 1b32dce1021a07c745b896a80c23c7ac 224 PRINTS PR00088 Haem oxygenase signature 46 71 3.2E-27 T 28-03-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 CU254_RS35070 1b32dce1021a07c745b896a80c23c7ac 224 PRINTS PR00088 Haem oxygenase signature 11 36 3.2E-27 T 28-03-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 CU254_RS35070 1b32dce1021a07c745b896a80c23c7ac 224 Pfam PF01126 Heme oxygenase 11 211 1.3E-50 T 28-03-2018 IPR016053 Haem oxygenase-like GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 CU254_RS35070 1b32dce1021a07c745b896a80c23c7ac 224 SUPERFAMILY SSF48613 11 213 4.3E-56 T 28-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CU254_RS35070 1b32dce1021a07c745b896a80c23c7ac 224 Gene3D G3DSA:1.20.910.10 2 221 5.4E-63 T 28-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CU254_RS35070 1b32dce1021a07c745b896a80c23c7ac 224 PIRSF PIRSF000343 1 222 2.4E-64 T 28-03-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 CU254_RS01485 51818834472e5e18db1d1c582fc274df 326 Gene3D G3DSA:3.90.550.10 4 294 1.0E-40 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS01485 51818834472e5e18db1d1c582fc274df 326 Pfam PF00535 Glycosyl transferase family 2 29 158 2.3E-18 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CU254_RS01485 51818834472e5e18db1d1c582fc274df 326 SUPERFAMILY SSF53448 23 282 2.87E-46 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS22225 f47d31c56565cad7cf8737fa606c5eb1 193 Gene3D G3DSA:3.40.430.10 4 186 1.6E-28 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CU254_RS22225 f47d31c56565cad7cf8737fa606c5eb1 193 SUPERFAMILY SSF53597 4 189 5.63E-22 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CU254_RS22225 f47d31c56565cad7cf8737fa606c5eb1 193 Pfam PF01872 RibD C-terminal domain 8 173 7.0E-10 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CU254_RS39050 46e9d549503600d97620b71825ff3d3c 245 Gene3D G3DSA:1.10.357.10 72 241 5.6E-25 T 28-03-2018 CU254_RS39050 46e9d549503600d97620b71825ff3d3c 245 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 62 1.5E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS39050 46e9d549503600d97620b71825ff3d3c 245 SUPERFAMILY SSF46689 6 78 5.99E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS39050 46e9d549503600d97620b71825ff3d3c 245 SUPERFAMILY SSF48498 90 238 6.45E-21 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS39050 46e9d549503600d97620b71825ff3d3c 245 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 9.7E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS39050 46e9d549503600d97620b71825ff3d3c 245 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 9.7E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS39050 46e9d549503600d97620b71825ff3d3c 245 Gene3D G3DSA:1.10.10.60 3 71 1.6E-16 T 28-03-2018 CU254_RS08910 3532ec737ff72ae5f8851e0712cc805d 150 Pfam PF00583 Acetyltransferase (GNAT) family 52 133 2.2E-10 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS08910 3532ec737ff72ae5f8851e0712cc805d 150 SUPERFAMILY SSF55729 5 141 6.13E-20 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS08910 3532ec737ff72ae5f8851e0712cc805d 150 Gene3D G3DSA:1.10.287.900 4 35 4.6E-15 T 28-03-2018 IPR027455 Spermine/spermidine acetyltransferase, N-terminal domain KEGG: 00330+2.3.1.57|MetaCyc: PWY-0|MetaCyc: PWY-6117 CU254_RS08910 3532ec737ff72ae5f8851e0712cc805d 150 Gene3D G3DSA:3.40.630.30 36 142 2.0E-15 T 28-03-2018 CU254_RS17045 fbc99d1ab5328089d06cf0949c3fa79c 145 Pfam PF13474 SnoaL-like domain 75 134 4.0E-8 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CU254_RS17045 fbc99d1ab5328089d06cf0949c3fa79c 145 Gene3D G3DSA:3.10.450.50 1 144 4.1E-15 T 28-03-2018 CU254_RS17045 fbc99d1ab5328089d06cf0949c3fa79c 145 SUPERFAMILY SSF54427 2 133 6.1E-12 T 28-03-2018 IPR032710 NTF2-like domain CU254_RS24985 e73ae3ad88d7e96d6faae2cbaff72c3d 340 Gene3D G3DSA:3.40.640.10 16 253 1.2E-19 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS24985 e73ae3ad88d7e96d6faae2cbaff72c3d 340 Gene3D G3DSA:3.90.1150.10 254 339 4.7E-5 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS24985 e73ae3ad88d7e96d6faae2cbaff72c3d 340 Pfam PF00266 Aminotransferase class-V 119 279 3.7E-9 T 28-03-2018 IPR000192 Aminotransferase class V domain CU254_RS24985 e73ae3ad88d7e96d6faae2cbaff72c3d 340 SUPERFAMILY SSF53383 14 338 8.8E-38 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS14890 c04e3529573efb4806b2802c3ce58ba7 265 SUPERFAMILY SSF46689 56 102 2.81E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS14890 c04e3529573efb4806b2802c3ce58ba7 265 Gene3D G3DSA:1.10.10.60 6 58 6.6E-12 T 28-03-2018 CU254_RS14890 c04e3529573efb4806b2802c3ce58ba7 265 SUPERFAMILY SSF46689 4 52 5.38E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS14890 c04e3529573efb4806b2802c3ce58ba7 265 Pfam PF12833 Helix-turn-helix domain 26 102 1.6E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS14890 c04e3529573efb4806b2802c3ce58ba7 265 SMART SM00342 19 102 1.1E-26 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS14890 c04e3529573efb4806b2802c3ce58ba7 265 Gene3D G3DSA:1.10.10.60 59 107 3.9E-12 T 28-03-2018 CU254_RS30610 c34238b2fb27648a94de1c99df61db5a 99 Gene3D G3DSA:3.30.70.1060 1 84 2.3E-5 T 28-03-2018 CU254_RS30610 c34238b2fb27648a94de1c99df61db5a 99 SUPERFAMILY SSF54909 1 82 2.28E-5 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS16865 39e93227d147494836c87b987e185c20 226 SUPERFAMILY SSF55781 16 157 6.67E-13 T 28-03-2018 IPR029016 GAF domain-like CU254_RS16865 39e93227d147494836c87b987e185c20 226 SMART SM01012 152 215 4.4E-8 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 CU254_RS16865 39e93227d147494836c87b987e185c20 226 Pfam PF03861 ANTAR domain 174 215 4.1E-9 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 CU254_RS16865 39e93227d147494836c87b987e185c20 226 PIRSF PIRSF036625 4 225 2.2E-31 T 28-03-2018 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative CU254_RS16865 39e93227d147494836c87b987e185c20 226 Pfam PF13185 GAF domain 15 143 1.2E-6 T 28-03-2018 IPR003018 GAF domain GO:0005515 CU254_RS16865 39e93227d147494836c87b987e185c20 226 Gene3D G3DSA:1.10.10.10 173 216 6.7E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS16865 39e93227d147494836c87b987e185c20 226 Gene3D G3DSA:3.30.450.40 1 163 1.4E-16 T 28-03-2018 IPR029016 GAF domain-like CU254_RS22930 b8ade51cbcf82e4068339bb6bc89f7c4 71 Pfam PF00872 Transposase, Mutator family 1 54 3.8E-7 T 28-03-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 CU254_RS28325 533f421fb0a6845590faa5c4617c6cfe 132 SUPERFAMILY SSF55298 7 131 4.71E-24 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CU254_RS28325 533f421fb0a6845590faa5c4617c6cfe 132 Gene3D G3DSA:3.30.1330.40 1 132 2.0E-25 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CU254_RS28325 533f421fb0a6845590faa5c4617c6cfe 132 Pfam PF01042 Endoribonuclease L-PSP 17 130 3.6E-18 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family CU254_RS25530 d70550dd2bd47df6767cce2e8171f43e 334 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 9 79 2.3E-13 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CU254_RS25530 d70550dd2bd47df6767cce2e8171f43e 334 SUPERFAMILY SSF63380 95 198 2.33E-25 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CU254_RS25530 d70550dd2bd47df6767cce2e8171f43e 334 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 35 43 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CU254_RS25530 d70550dd2bd47df6767cce2e8171f43e 334 Pfam PF00970 Oxidoreductase FAD-binding domain 102 194 1.6E-16 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CU254_RS25530 d70550dd2bd47df6767cce2e8171f43e 334 Gene3D G3DSA:3.40.50.80 197 334 3.2E-23 T 28-03-2018 CU254_RS25530 d70550dd2bd47df6767cce2e8171f43e 334 SUPERFAMILY SSF52343 201 331 1.31E-33 T 28-03-2018 CU254_RS25530 d70550dd2bd47df6767cce2e8171f43e 334 Pfam PF00175 Oxidoreductase NAD-binding domain 209 309 4.3E-15 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CU254_RS25530 d70550dd2bd47df6767cce2e8171f43e 334 Gene3D G3DSA:2.40.30.10 98 196 4.4E-23 T 28-03-2018 CU254_RS25530 d70550dd2bd47df6767cce2e8171f43e 334 Gene3D G3DSA:3.10.20.30 1 97 3.2E-22 T 28-03-2018 IPR012675 Beta-grasp domain CU254_RS25530 d70550dd2bd47df6767cce2e8171f43e 334 PRINTS PR00410 Phenol hydroxylase reductase family signature 297 305 6.2E-18 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CU254_RS25530 d70550dd2bd47df6767cce2e8171f43e 334 PRINTS PR00410 Phenol hydroxylase reductase family signature 208 227 6.2E-18 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CU254_RS25530 d70550dd2bd47df6767cce2e8171f43e 334 PRINTS PR00410 Phenol hydroxylase reductase family signature 127 139 6.2E-18 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CU254_RS25530 d70550dd2bd47df6767cce2e8171f43e 334 PRINTS PR00410 Phenol hydroxylase reductase family signature 144 151 6.2E-18 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CU254_RS25530 d70550dd2bd47df6767cce2e8171f43e 334 PRINTS PR00410 Phenol hydroxylase reductase family signature 233 242 6.2E-18 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CU254_RS25530 d70550dd2bd47df6767cce2e8171f43e 334 SUPERFAMILY SSF54292 4 87 1.97E-25 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CU254_RS23120 2392ef6cdd69439e4e37bb69fc7ec70b 210 Pfam PF02441 Flavoprotein 23 195 2.0E-20 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CU254_RS23120 2392ef6cdd69439e4e37bb69fc7ec70b 210 SUPERFAMILY SSF52507 23 197 1.23E-22 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CU254_RS23120 2392ef6cdd69439e4e37bb69fc7ec70b 210 Gene3D G3DSA:3.40.50.1950 20 206 2.2E-22 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CU254_RS19055 3b1a00fc7d1f43cfc5c5a20464f1fa06 538 SUPERFAMILY SSF47203 285 438 9.5E-38 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS19055 3b1a00fc7d1f43cfc5c5a20464f1fa06 538 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 176 270 1.1E-15 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CU254_RS19055 3b1a00fc7d1f43cfc5c5a20464f1fa06 538 Gene3D G3DSA:2.40.110.10 172 268 2.6E-22 T 28-03-2018 CU254_RS19055 3b1a00fc7d1f43cfc5c5a20464f1fa06 538 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 393 412 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CU254_RS19055 3b1a00fc7d1f43cfc5c5a20464f1fa06 538 Gene3D G3DSA:1.20.140.10 269 444 1.1E-30 T 28-03-2018 CU254_RS19055 3b1a00fc7d1f43cfc5c5a20464f1fa06 538 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 280 434 3.2E-26 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS19055 3b1a00fc7d1f43cfc5c5a20464f1fa06 538 SUPERFAMILY SSF56645 54 289 2.26E-40 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS31405 4429d54e0a7d12355e04ada186c459aa 278 Pfam PF11303 Protein of unknown function (DUF3105) 98 225 5.2E-44 T 28-03-2018 IPR021454 Protein of unknown function DUF3105 CU254_RS34865 68bf305283f17bce513acde3b5a67529 191 Gene3D G3DSA:1.10.357.10 62 187 1.8E-23 T 28-03-2018 CU254_RS34865 68bf305283f17bce513acde3b5a67529 191 SUPERFAMILY SSF48498 79 184 3.4E-23 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS34865 68bf305283f17bce513acde3b5a67529 191 SUPERFAMILY SSF46689 6 73 2.21E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS34865 68bf305283f17bce513acde3b5a67529 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 58 5.1E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS34865 68bf305283f17bce513acde3b5a67529 191 Gene3D G3DSA:1.10.10.60 5 61 1.1E-14 T 28-03-2018 CU254_RS30695 5ae658d075f7b46713a2e2d720735be9 304 Gene3D G3DSA:3.40.50.720 1 301 1.3E-49 T 28-03-2018 CU254_RS30695 5ae658d075f7b46713a2e2d720735be9 304 Pfam PF00106 short chain dehydrogenase 17 208 8.1E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS30695 5ae658d075f7b46713a2e2d720735be9 304 SUPERFAMILY SSF51735 8 252 3.23E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS30695 5ae658d075f7b46713a2e2d720735be9 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 8.9E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS30695 5ae658d075f7b46713a2e2d720735be9 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 193 8.9E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS30695 5ae658d075f7b46713a2e2d720735be9 304 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 90 101 8.9E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS06965 2c916cb61607d3eed07c615d79fe67d6 299 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 29 40 3.8E-9 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CU254_RS06965 2c916cb61607d3eed07c615d79fe67d6 299 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 134 147 3.8E-9 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CU254_RS06965 2c916cb61607d3eed07c615d79fe67d6 299 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 165 181 3.8E-9 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CU254_RS06965 2c916cb61607d3eed07c615d79fe67d6 299 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 211 224 3.8E-9 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CU254_RS06965 2c916cb61607d3eed07c615d79fe67d6 299 Gene3D G3DSA:3.40.50.1000 102 258 1.5E-31 T 28-03-2018 IPR023214 HAD-like domain CU254_RS06965 2c916cb61607d3eed07c615d79fe67d6 299 Pfam PF13419 Haloacid dehalogenase-like hydrolase 35 221 3.7E-18 T 28-03-2018 IPR023214 HAD-like domain CU254_RS06965 2c916cb61607d3eed07c615d79fe67d6 299 SUPERFAMILY SSF56784 31 251 1.96E-41 T 28-03-2018 IPR023214 HAD-like domain CU254_RS06965 2c916cb61607d3eed07c615d79fe67d6 299 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 136 216 1.5E-9 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CU254_RS23575 ea0ec60c4eb847556b591df3861bb701 396 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 142 3.0E-28 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CU254_RS23575 ea0ec60c4eb847556b591df3861bb701 396 SUPERFAMILY SSF50129 1 191 3.5E-60 T 28-03-2018 IPR011032 GroES-like CU254_RS23575 ea0ec60c4eb847556b591df3861bb701 396 SUPERFAMILY SSF51735 156 351 2.34E-48 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS23575 ea0ec60c4eb847556b591df3861bb701 396 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CU254_RS23575 ea0ec60c4eb847556b591df3861bb701 396 Gene3D G3DSA:3.90.180.10 1 172 3.1E-47 T 28-03-2018 CU254_RS23575 ea0ec60c4eb847556b591df3861bb701 396 Pfam PF00107 Zinc-binding dehydrogenase 189 258 7.7E-14 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CU254_RS23575 ea0ec60c4eb847556b591df3861bb701 396 Pfam PF13823 Alcohol dehydrogenase GroES-associated 1 23 2.3E-14 T 28-03-2018 IPR027399 Alcohol dehydrogenase GroES-associated CU254_RS23575 ea0ec60c4eb847556b591df3861bb701 396 Gene3D G3DSA:3.40.50.720 173 347 2.5E-32 T 28-03-2018 CU254_RS09275 a8e14ab46993e855f7316d000b54d13d 127 SUPERFAMILY SSF50475 4 116 4.49E-17 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS09275 a8e14ab46993e855f7316d000b54d13d 127 TIGRFAM TIGR03666 Rv2061_F420: PPOX class probable F420-dependent enzyme, Rv2061 family 3 126 2.3E-44 T 28-03-2018 IPR019965 PPOX class F420-dependent enzyme, family Rv2061, putative CU254_RS09275 a8e14ab46993e855f7316d000b54d13d 127 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 6 85 3.9E-9 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CU254_RS09275 a8e14ab46993e855f7316d000b54d13d 127 Gene3D G3DSA:2.30.110.10 2 119 7.6E-19 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS14950 b4aa69c7f7faf024c944ae0e35f88d20 176 SUPERFAMILY SSF46689 8 67 1.74E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS14950 b4aa69c7f7faf024c944ae0e35f88d20 176 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 57 5.5E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS14950 b4aa69c7f7faf024c944ae0e35f88d20 176 Gene3D G3DSA:1.10.357.10 2 175 2.3E-22 T 28-03-2018 CU254_RS24505 6dc107cb97e6476c564e044945bbb9c1 247 SUPERFAMILY SSF51419 8 240 6.02E-59 T 28-03-2018 IPR029066 PLP-binding barrel CU254_RS24505 6dc107cb97e6476c564e044945bbb9c1 247 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 16 242 2.4E-39 T 28-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein CU254_RS24505 6dc107cb97e6476c564e044945bbb9c1 247 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 89 103 - T 28-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein CU254_RS24505 6dc107cb97e6476c564e044945bbb9c1 247 Gene3D G3DSA:3.20.20.10 1 246 2.0E-55 T 28-03-2018 IPR029066 PLP-binding barrel CU254_RS24505 6dc107cb97e6476c564e044945bbb9c1 247 Pfam PF01168 Alanine racemase, N-terminal domain 16 242 1.5E-17 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CU254_RS24505 6dc107cb97e6476c564e044945bbb9c1 247 PIRSF PIRSF004848 6 246 4.4E-60 T 28-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein CU254_RS12260 87b17bfb002a3cbd9cc6cd1363157d1e 191 SUPERFAMILY SSF53597 3 190 2.23E-23 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CU254_RS12260 87b17bfb002a3cbd9cc6cd1363157d1e 191 Pfam PF01872 RibD C-terminal domain 2 183 1.9E-33 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CU254_RS12260 87b17bfb002a3cbd9cc6cd1363157d1e 191 Gene3D G3DSA:3.40.430.10 3 188 2.6E-29 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CU254_RS24635 90922f9b193872d071b3d430a191465e 143 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 1 128 9.0E-48 T 28-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 CU254_RS24635 90922f9b193872d071b3d430a191465e 143 SUPERFAMILY SSF89447 2 135 2.09E-45 T 28-03-2018 CU254_RS24635 90922f9b193872d071b3d430a191465e 143 Pfam PF02381 MraZ protein, putative antitoxin-like 72 137 9.8E-20 T 28-03-2018 IPR020603 MraZ domain CU254_RS24635 90922f9b193872d071b3d430a191465e 143 Pfam PF02381 MraZ protein, putative antitoxin-like 2 70 2.5E-21 T 28-03-2018 IPR020603 MraZ domain CU254_RS24635 90922f9b193872d071b3d430a191465e 143 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 143 51.677 T 28-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 CU254_RS24635 90922f9b193872d071b3d430a191465e 143 Gene3D G3DSA:2.10.260.10 4 28 2.9E-5 T 28-03-2018 CU254_RS24635 90922f9b193872d071b3d430a191465e 143 Gene3D G3DSA:2.10.260.10 78 124 7.7E-5 T 28-03-2018 CU254_RS24635 90922f9b193872d071b3d430a191465e 143 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 2 136 4.6E-38 T 28-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 CU254_RS10235 cba221f1e2c7ba5ff99e52368facbcaa 146 Pfam PF04341 Protein of unknown function, DUF485 48 134 4.8E-33 T 28-03-2018 IPR007436 Protein of unknown function DUF485 CU254_RS10235 cba221f1e2c7ba5ff99e52368facbcaa 146 Gene3D G3DSA:1.20.1250.20 43 133 2.2E-4 T 28-03-2018 CU254_RS18180 82f923dff01d3582d705b49a2e6375ba 276 Pfam PF14801 tRNA methyltransferase complex GCD14 subunit N-term 4 54 6.2E-29 T 28-03-2018 CU254_RS18180 82f923dff01d3582d705b49a2e6375ba 276 Pfam PF08704 tRNA methyltransferase complex GCD14 subunit 73 234 2.2E-23 T 28-03-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829 CU254_RS18180 82f923dff01d3582d705b49a2e6375ba 276 Gene3D G3DSA:3.10.330.20 6 67 6.4E-25 T 28-03-2018 CU254_RS18180 82f923dff01d3582d705b49a2e6375ba 276 Gene3D G3DSA:3.40.50.150 69 264 5.8E-36 T 28-03-2018 CU254_RS18180 82f923dff01d3582d705b49a2e6375ba 276 PIRSF PIRSF017269 1 267 2.7E-86 T 28-03-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829 CU254_RS18180 82f923dff01d3582d705b49a2e6375ba 276 SUPERFAMILY SSF53335 6 257 5.07E-73 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS32125 fefa7441a30ef51c05e94488a2ca30c5 287 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 190 4.4E-4 T 28-03-2018 CU254_RS32125 fefa7441a30ef51c05e94488a2ca30c5 287 SUPERFAMILY SSF51735 5 250 3.48E-68 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS32125 fefa7441a30ef51c05e94488a2ca30c5 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 3.9E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS32125 fefa7441a30ef51c05e94488a2ca30c5 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 3.9E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS32125 fefa7441a30ef51c05e94488a2ca30c5 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 3.9E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS32125 fefa7441a30ef51c05e94488a2ca30c5 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 3.9E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS32125 fefa7441a30ef51c05e94488a2ca30c5 287 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 3.9E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS32125 fefa7441a30ef51c05e94488a2ca30c5 287 Gene3D G3DSA:3.40.50.720 1 260 2.9E-60 T 28-03-2018 CU254_RS32125 fefa7441a30ef51c05e94488a2ca30c5 287 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 5.9E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS32125 fefa7441a30ef51c05e94488a2ca30c5 287 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 5.9E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS32125 fefa7441a30ef51c05e94488a2ca30c5 287 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 5.9E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS32125 fefa7441a30ef51c05e94488a2ca30c5 287 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS32125 fefa7441a30ef51c05e94488a2ca30c5 287 Pfam PF00106 short chain dehydrogenase 9 196 1.2E-52 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS17245 6bd0a865e00403b33185a6c99b27c558 388 Pfam PF00108 Thiolase, N-terminal domain 5 258 1.9E-60 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CU254_RS17245 6bd0a865e00403b33185a6c99b27c558 388 Gene3D G3DSA:3.40.47.10 261 385 3.3E-34 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS17245 6bd0a865e00403b33185a6c99b27c558 388 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 386 1.5E-133 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CU254_RS17245 6bd0a865e00403b33185a6c99b27c558 388 Gene3D G3DSA:3.40.47.10 1 260 3.7E-50 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS17245 6bd0a865e00403b33185a6c99b27c558 388 PIRSF PIRSF000429 1 388 7.5E-119 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CU254_RS17245 6bd0a865e00403b33185a6c99b27c558 388 SUPERFAMILY SSF53901 263 388 1.56E-41 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS17245 6bd0a865e00403b33185a6c99b27c558 388 SUPERFAMILY SSF53901 4 265 1.43E-67 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS17245 6bd0a865e00403b33185a6c99b27c558 388 ProSitePatterns PS00737 Thiolases signature 2. 334 350 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CU254_RS17245 6bd0a865e00403b33185a6c99b27c558 388 Pfam PF02803 Thiolase, C-terminal domain 266 387 7.3E-44 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CU254_RS30150 9b5c7a755480d4237e05ff254dd184a4 398 Pfam PF00067 Cytochrome P450 184 368 2.3E-21 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS30150 9b5c7a755480d4237e05ff254dd184a4 398 SUPERFAMILY SSF48264 17 398 1.26E-92 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS30150 9b5c7a755480d4237e05ff254dd184a4 398 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 340 349 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CU254_RS30150 9b5c7a755480d4237e05ff254dd184a4 398 PRINTS PR00385 P450 superfamily signature 347 358 4.1E-7 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS30150 9b5c7a755480d4237e05ff254dd184a4 398 PRINTS PR00385 P450 superfamily signature 338 347 4.1E-7 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS30150 9b5c7a755480d4237e05ff254dd184a4 398 PRINTS PR00385 P450 superfamily signature 235 252 4.1E-7 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS30150 9b5c7a755480d4237e05ff254dd184a4 398 PRINTS PR00385 P450 superfamily signature 270 281 4.1E-7 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS30150 9b5c7a755480d4237e05ff254dd184a4 398 PRINTS PR00359 B-class P450 signature 133 149 5.6E-63 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS30150 9b5c7a755480d4237e05ff254dd184a4 398 PRINTS PR00359 B-class P450 signature 150 165 5.6E-63 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS30150 9b5c7a755480d4237e05ff254dd184a4 398 PRINTS PR00359 B-class P450 signature 347 358 5.6E-63 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS30150 9b5c7a755480d4237e05ff254dd184a4 398 PRINTS PR00359 B-class P450 signature 317 332 5.6E-63 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS30150 9b5c7a755480d4237e05ff254dd184a4 398 PRINTS PR00359 B-class P450 signature 270 281 5.6E-63 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS30150 9b5c7a755480d4237e05ff254dd184a4 398 PRINTS PR00359 B-class P450 signature 86 97 5.6E-63 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS30150 9b5c7a755480d4237e05ff254dd184a4 398 PRINTS PR00359 B-class P450 signature 338 347 5.6E-63 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS30150 9b5c7a755480d4237e05ff254dd184a4 398 PRINTS PR00359 B-class P450 signature 289 316 5.6E-63 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS30150 9b5c7a755480d4237e05ff254dd184a4 398 PRINTS PR00359 B-class P450 signature 188 210 5.6E-63 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS30150 9b5c7a755480d4237e05ff254dd184a4 398 Gene3D G3DSA:1.10.630.10 3 398 5.5E-77 T 28-03-2018 CU254_RS18865 ad35c6a741d7a2874a2d322d5675a542 249 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 24 213 6.2E-33 T 28-03-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 CU254_RS18865 ad35c6a741d7a2874a2d322d5675a542 249 SUPERFAMILY SSF51621 2 220 1.41E-63 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CU254_RS18865 ad35c6a741d7a2874a2d322d5675a542 249 Gene3D G3DSA:3.20.20.60 1 233 2.5E-39 T 28-03-2018 CU254_RS10975 4413723a124cc6e286c84e128fda0ccc 547 Gene3D G3DSA:3.40.50.970 2 202 1.4E-38 T 28-03-2018 CU254_RS10975 4413723a124cc6e286c84e128fda0ccc 547 SUPERFAMILY SSF52518 2 188 2.55E-35 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS10975 4413723a124cc6e286c84e128fda0ccc 547 SUPERFAMILY SSF52467 167 351 5.0E-36 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CU254_RS10975 4413723a124cc6e286c84e128fda0ccc 547 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 397 531 8.0E-26 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CU254_RS10975 4413723a124cc6e286c84e128fda0ccc 547 Gene3D G3DSA:3.40.50.1220 203 363 1.1E-34 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CU254_RS10975 4413723a124cc6e286c84e128fda0ccc 547 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 203 334 3.9E-31 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CU254_RS10975 4413723a124cc6e286c84e128fda0ccc 547 Gene3D G3DSA:3.40.50.970 364 534 8.3E-29 T 28-03-2018 CU254_RS10975 4413723a124cc6e286c84e128fda0ccc 547 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 5 182 3.6E-40 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CU254_RS10975 4413723a124cc6e286c84e128fda0ccc 547 SUPERFAMILY SSF52518 373 534 7.68E-34 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS17615 eed7f13768585487e85a75706608196c 225 SUPERFAMILY SSF56784 5 224 3.05E-39 T 28-03-2018 IPR023214 HAD-like domain CU254_RS17615 eed7f13768585487e85a75706608196c 225 Gene3D G3DSA:3.40.50.1000 3 225 1.2E-27 T 28-03-2018 IPR023214 HAD-like domain CU254_RS17615 eed7f13768585487e85a75706608196c 225 Pfam PF13419 Haloacid dehalogenase-like hydrolase 10 192 6.1E-15 T 28-03-2018 IPR023214 HAD-like domain CU254_RS17615 eed7f13768585487e85a75706608196c 225 TIGRFAM TIGR03351 PhnX-like: phosphonatase-like hydrolase 5 223 3.5E-67 T 28-03-2018 IPR022468 Phosphonatase-like hydrolase CU254_RS31425 1ae58f34c1451a1d1a297e7307cfc710 306 Gene3D G3DSA:3.30.70.1350 218 298 1.0E-13 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CU254_RS31425 1ae58f34c1451a1d1a297e7307cfc710 306 SUPERFAMILY SSF160240 223 293 1.83E-8 T 28-03-2018 CU254_RS31425 1ae58f34c1451a1d1a297e7307cfc710 306 Pfam PF01545 Cation efflux family 24 215 1.5E-41 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CU254_RS31425 1ae58f34c1451a1d1a297e7307cfc710 306 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 22 293 5.4E-77 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CU254_RS31425 1ae58f34c1451a1d1a297e7307cfc710 306 Gene3D G3DSA:1.20.1510.10 20 216 2.2E-53 T 28-03-2018 CU254_RS31425 1ae58f34c1451a1d1a297e7307cfc710 306 SUPERFAMILY SSF161111 19 217 5.23E-51 T 28-03-2018 CU254_RS05895 d9bd3bdf89b7cc2a77d4a3754f255f93 254 SMART SM00563 39 153 6.7E-40 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CU254_RS05895 d9bd3bdf89b7cc2a77d4a3754f255f93 254 Gene3D G3DSA:3.40.1130.10 6 220 1.4E-50 T 28-03-2018 CU254_RS05895 d9bd3bdf89b7cc2a77d4a3754f255f93 254 SUPERFAMILY SSF69593 21 216 2.22E-38 T 28-03-2018 CU254_RS05895 d9bd3bdf89b7cc2a77d4a3754f255f93 254 Pfam PF01553 Acyltransferase 29 150 2.2E-30 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CU254_RS19175 b9731aa0f1b5593dfcf9d44737f39af4 373 Pfam PF01494 FAD binding domain 140 345 3.5E-10 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CU254_RS19175 b9731aa0f1b5593dfcf9d44737f39af4 373 SUPERFAMILY SSF51905 3 167 8.46E-44 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS19175 b9731aa0f1b5593dfcf9d44737f39af4 373 SUPERFAMILY SSF51905 271 367 8.46E-44 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS19175 b9731aa0f1b5593dfcf9d44737f39af4 373 Gene3D G3DSA:3.50.50.60 1 369 1.7E-37 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS19175 b9731aa0f1b5593dfcf9d44737f39af4 373 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 1.5E-13 T 28-03-2018 CU254_RS19175 b9731aa0f1b5593dfcf9d44737f39af4 373 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 286 301 1.5E-13 T 28-03-2018 CU254_RS19175 b9731aa0f1b5593dfcf9d44737f39af4 373 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 146 161 1.5E-13 T 28-03-2018 CU254_RS18680 3728b97e4423d39c3a3f2a283d695ebf 380 Pfam PF02515 CoA-transferase family III 6 373 5.5E-59 T 28-03-2018 IPR003673 CoA-transferase family III GO:0003824 CU254_RS18680 3728b97e4423d39c3a3f2a283d695ebf 380 SUPERFAMILY SSF89796 3 379 2.35E-72 T 28-03-2018 IPR023606 CoA-transferase family III domain CU254_RS18680 3728b97e4423d39c3a3f2a283d695ebf 380 Gene3D G3DSA:3.40.50.10540 1 380 6.2E-77 T 28-03-2018 IPR023606 CoA-transferase family III domain CU254_RS06870 6caa2615e66e5803aea4e1026bfdb198 274 Gene3D G3DSA:3.40.50.10780 3 214 4.6E-78 T 28-03-2018 IPR027476 D-aminopeptidase, N-terminal CU254_RS06870 6caa2615e66e5803aea4e1026bfdb198 274 Pfam PF04951 D-aminopeptidase 3 266 8.7E-90 T 28-03-2018 IPR007035 Peptidase M55, D-aminopeptidase CU254_RS06870 6caa2615e66e5803aea4e1026bfdb198 274 SUPERFAMILY SSF63992 3 272 5.89E-80 T 28-03-2018 IPR007035 Peptidase M55, D-aminopeptidase CU254_RS06870 6caa2615e66e5803aea4e1026bfdb198 274 Gene3D G3DSA:3.30.1360.130 215 273 8.0E-13 T 28-03-2018 CU254_RS06870 6caa2615e66e5803aea4e1026bfdb198 274 PIRSF PIRSF015853 3 274 1.9E-80 T 28-03-2018 IPR007035 Peptidase M55, D-aminopeptidase CU254_RS39565 901744ea2c79c2651af632ef2c9a0691 251 Pfam PF00089 Trypsin 29 246 8.3E-23 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CU254_RS39565 901744ea2c79c2651af632ef2c9a0691 251 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 62 77 3.3E-10 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CU254_RS39565 901744ea2c79c2651af632ef2c9a0691 251 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 197 209 3.3E-10 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CU254_RS39565 901744ea2c79c2651af632ef2c9a0691 251 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 119 133 3.3E-10 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CU254_RS39565 901744ea2c79c2651af632ef2c9a0691 251 Gene3D G3DSA:2.40.10.10 27 67 3.9E-11 T 28-03-2018 CU254_RS39565 901744ea2c79c2651af632ef2c9a0691 251 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 72 77 - T 28-03-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 CU254_RS39565 901744ea2c79c2651af632ef2c9a0691 251 SUPERFAMILY SSF50494 17 250 2.36E-36 T 28-03-2018 IPR009003 Peptidase S1, PA clan CU254_RS39565 901744ea2c79c2651af632ef2c9a0691 251 Gene3D G3DSA:2.40.10.10 133 251 1.3E-16 T 28-03-2018 CU254_RS39565 901744ea2c79c2651af632ef2c9a0691 251 Gene3D G3DSA:2.40.10.10 68 132 1.0E-13 T 28-03-2018 CU254_RS39565 901744ea2c79c2651af632ef2c9a0691 251 SMART SM00020 26 246 4.6E-14 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CU254_RS33350 9d6630930675a0a5f4cde0c04b34c62a 323 SUPERFAMILY SSF52540 6 234 1.57E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS33350 9d6630930675a0a5f4cde0c04b34c62a 323 SMART SM00382 31 212 6.3E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS33350 9d6630930675a0a5f4cde0c04b34c62a 323 Gene3D G3DSA:3.40.50.300 2 321 1.0E-74 T 28-03-2018 CU254_RS33350 9d6630930675a0a5f4cde0c04b34c62a 323 Pfam PF00005 ABC transporter 23 163 1.6E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS33350 9d6630930675a0a5f4cde0c04b34c62a 323 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 212 307 1.3E-16 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CU254_RS33350 9d6630930675a0a5f4cde0c04b34c62a 323 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 214 275 1.2E-14 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CU254_RS33350 9d6630930675a0a5f4cde0c04b34c62a 323 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS03760 e9fe8081d1b455aa3847a18583add6d5 204 Pfam PF04542 Sigma-70 region 2 37 102 6.6E-21 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS03760 e9fe8081d1b455aa3847a18583add6d5 204 SUPERFAMILY SSF88659 111 191 1.48E-17 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS03760 e9fe8081d1b455aa3847a18583add6d5 204 Pfam PF08281 Sigma-70, region 4 135 185 3.2E-17 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS03760 e9fe8081d1b455aa3847a18583add6d5 204 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 33 187 2.2E-31 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS03760 e9fe8081d1b455aa3847a18583add6d5 204 Gene3D G3DSA:1.10.1740.10 20 99 6.7E-24 T 28-03-2018 CU254_RS03760 e9fe8081d1b455aa3847a18583add6d5 204 SUPERFAMILY SSF88946 32 115 6.75E-25 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS03760 e9fe8081d1b455aa3847a18583add6d5 204 Gene3D G3DSA:1.10.10.10 100 198 3.5E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS33830 a9c7784b96d05d59107615c69ae2f3b7 337 SMART SM00930 254 327 0.0084 T 28-03-2018 IPR018449 NIL domain CU254_RS33830 a9c7784b96d05d59107615c69ae2f3b7 337 SMART SM00382 30 217 8.9E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS33830 a9c7784b96d05d59107615c69ae2f3b7 337 Gene3D G3DSA:3.30.70.260 249 327 7.4E-8 T 28-03-2018 CU254_RS33830 a9c7784b96d05d59107615c69ae2f3b7 337 Pfam PF00005 ABC transporter 21 169 3.6E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS33830 a9c7784b96d05d59107615c69ae2f3b7 337 SUPERFAMILY SSF52540 1 237 4.18E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS33830 a9c7784b96d05d59107615c69ae2f3b7 337 Gene3D G3DSA:3.40.50.300 1 248 2.1E-63 T 28-03-2018 CU254_RS33830 a9c7784b96d05d59107615c69ae2f3b7 337 SUPERFAMILY SSF55021 251 324 8.58E-5 T 28-03-2018 CU254_RS33830 a9c7784b96d05d59107615c69ae2f3b7 337 Pfam PF09383 NIL domain 258 324 9.0E-7 T 28-03-2018 IPR018449 NIL domain CU254_RS29350 b28f10f6e0ccb32fe7c671c5a126887c 442 Gene3D G3DSA:1.20.1250.20 12 223 4.3E-36 T 28-03-2018 CU254_RS29350 b28f10f6e0ccb32fe7c671c5a126887c 442 SUPERFAMILY SSF103473 13 436 7.59E-74 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS29350 b28f10f6e0ccb32fe7c671c5a126887c 442 Pfam PF07690 Major Facilitator Superfamily 29 396 1.5E-39 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS29350 b28f10f6e0ccb32fe7c671c5a126887c 442 Gene3D G3DSA:1.20.1250.20 240 438 5.5E-17 T 28-03-2018 CU254_RS38295 ee2798cfea07399e48adfee98ed8143d 196 Gene3D G3DSA:1.10.357.10 54 185 2.8E-19 T 28-03-2018 CU254_RS38295 ee2798cfea07399e48adfee98ed8143d 196 SUPERFAMILY SSF46689 3 74 2.98E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS38295 ee2798cfea07399e48adfee98ed8143d 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 1.6E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS38295 ee2798cfea07399e48adfee98ed8143d 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 1.6E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS38295 ee2798cfea07399e48adfee98ed8143d 196 Gene3D G3DSA:1.10.10.60 1 53 2.7E-17 T 28-03-2018 CU254_RS38295 ee2798cfea07399e48adfee98ed8143d 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 55 3.9E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS38295 ee2798cfea07399e48adfee98ed8143d 196 ProSitePatterns PS01081 TetR-type HTH domain signature. 24 55 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CU254_RS12485 073f32ce6e07be878c8ee7eb9abd9170 140 Gene3D G3DSA:1.20.210.10 1 140 3.6E-4 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CU254_RS12485 073f32ce6e07be878c8ee7eb9abd9170 140 Pfam PF11070 Protein of unknown function (DUF2871) 3 129 4.8E-45 T 28-03-2018 IPR021299 Protein of unknown function DUF2871 CU254_RS10330 e87d9f653baadee622df77371c389e91 182 Gene3D G3DSA:1.10.357.10 63 180 4.0E-22 T 28-03-2018 CU254_RS10330 e87d9f653baadee622df77371c389e91 182 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 53 8.6E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS10330 e87d9f653baadee622df77371c389e91 182 Gene3D G3DSA:1.10.10.60 1 62 4.3E-14 T 28-03-2018 CU254_RS10330 e87d9f653baadee622df77371c389e91 182 SUPERFAMILY SSF46689 4 59 6.67E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS10330 e87d9f653baadee622df77371c389e91 182 Pfam PF16859 Bacterial transcriptional repressor C-terminal 70 175 8.1E-21 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS10330 e87d9f653baadee622df77371c389e91 182 SUPERFAMILY SSF48498 71 179 4.45E-16 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS28890 0dab3e508bd3238f5f6a23c3d61ef4bf 207 Gene3D G3DSA:1.10.260.40 42 72 1.5E-10 T 28-03-2018 CU254_RS28890 0dab3e508bd3238f5f6a23c3d61ef4bf 207 Gene3D G3DSA:1.10.10.60 8 41 4.8E-16 T 28-03-2018 CU254_RS28890 0dab3e508bd3238f5f6a23c3d61ef4bf 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 2.1E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS28890 0dab3e508bd3238f5f6a23c3d61ef4bf 207 SUPERFAMILY SSF46689 6 80 4.0E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS26110 3e55bee9a2eef3a2d7dfce63e2d2bef4 132 SUPERFAMILY SSF47413 25 68 1.88E-6 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS26110 3e55bee9a2eef3a2d7dfce63e2d2bef4 132 Pfam PF01381 Helix-turn-helix 8 62 5.7E-6 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS26110 3e55bee9a2eef3a2d7dfce63e2d2bef4 132 Gene3D G3DSA:1.10.260.40 2 79 3.8E-13 T 28-03-2018 CU254_RS38160 36718eccc71a4c07826ea788a5d087d7 274 SMART SM00382 35 239 1.1E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS38160 36718eccc71a4c07826ea788a5d087d7 274 Pfam PF00005 ABC transporter 27 183 5.6E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS38160 36718eccc71a4c07826ea788a5d087d7 274 Gene3D G3DSA:3.40.50.300 7 269 2.3E-50 T 28-03-2018 CU254_RS38160 36718eccc71a4c07826ea788a5d087d7 274 SUPERFAMILY SSF52540 9 240 1.81E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS33535 7d7bf15e96c520a6d5ddad0d11933152 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 307 2.4E-32 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS33535 7d7bf15e96c520a6d5ddad0d11933152 308 Gene3D G3DSA:1.10.3720.10 2 299 3.4E-38 T 28-03-2018 CU254_RS33535 7d7bf15e96c520a6d5ddad0d11933152 308 SUPERFAMILY SSF161098 90 294 3.49E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS21910 6e19a6bc6ccdaf5d7ac6140960b13431 434 SUPERFAMILY SSF48230 99 379 2.11E-51 T 28-03-2018 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 CU254_RS21910 6e19a6bc6ccdaf5d7ac6140960b13431 434 Gene3D G3DSA:1.50.10.100 82 406 2.9E-48 T 28-03-2018 CU254_RS21910 6e19a6bc6ccdaf5d7ac6140960b13431 434 Pfam PF05426 Alginate lyase 94 376 3.0E-83 T 28-03-2018 IPR008397 Alginate lyase domain GO:0016829|GO:0042597 KEGG: 00051+4.2.2.3|MetaCyc: PWY-6986 CU254_RS08640 3d2fa2cdbf203949c5ee55a32827e1ee 541 SMART SM00939 302 535 1.8E-54 T 28-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CU254_RS08640 3d2fa2cdbf203949c5ee55a32827e1ee 541 SUPERFAMILY SSF53474 24 337 4.24E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS08640 3d2fa2cdbf203949c5ee55a32827e1ee 541 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 32 289 2.5E-49 T 28-03-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 CU254_RS08640 3d2fa2cdbf203949c5ee55a32827e1ee 541 Gene3D G3DSA:2.60.120.260 333 539 6.5E-54 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS08640 3d2fa2cdbf203949c5ee55a32827e1ee 541 SUPERFAMILY SSF49785 331 538 1.64E-46 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS08640 3d2fa2cdbf203949c5ee55a32827e1ee 541 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 28 539 1.6E-94 T 28-03-2018 IPR005674 CocE/Serine esterase GO:0016787 CU254_RS08640 3d2fa2cdbf203949c5ee55a32827e1ee 541 Gene3D G3DSA:3.40.50.1820 14 332 4.6E-36 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS08640 3d2fa2cdbf203949c5ee55a32827e1ee 541 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 319 534 5.4E-32 T 28-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CU254_RS38095 50b3e1170ea2944ca15b399da1f2c63c 194 SUPERFAMILY SSF46689 8 75 4.21E-19 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS38095 50b3e1170ea2944ca15b399da1f2c63c 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 57 1.6E-19 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS38095 50b3e1170ea2944ca15b399da1f2c63c 194 Gene3D G3DSA:1.10.10.60 8 41 2.4E-21 T 28-03-2018 CU254_RS38095 50b3e1170ea2944ca15b399da1f2c63c 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 1.2E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS38095 50b3e1170ea2944ca15b399da1f2c63c 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 1.2E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS38095 50b3e1170ea2944ca15b399da1f2c63c 194 Gene3D G3DSA:1.10.260.40 42 194 3.8E-13 T 28-03-2018 CU254_RS20265 fdfd701785574a597224fe036a614e5b 280 Pfam PF00378 Enoyl-CoA hydratase/isomerase 22 279 3.8E-51 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CU254_RS20265 fdfd701785574a597224fe036a614e5b 280 SUPERFAMILY SSF52096 11 279 1.23E-75 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS20265 fdfd701785574a597224fe036a614e5b 280 Gene3D G3DSA:1.10.12.10 230 279 1.2E-16 T 28-03-2018 IPR014748 Crontonase, C-terminal CU254_RS20265 fdfd701785574a597224fe036a614e5b 280 Gene3D G3DSA:3.90.226.10 8 229 2.0E-56 T 28-03-2018 CU254_RS20265 fdfd701785574a597224fe036a614e5b 280 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 120 140 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CU254_RS21420 46fefd5956d74acbcbec6a189ddf7f72 293 SUPERFAMILY SSF50891 130 292 8.77E-32 T 28-03-2018 IPR029000 Cyclophilin-like domain CU254_RS21420 46fefd5956d74acbcbec6a189ddf7f72 293 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 132 291 1.2E-28 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CU254_RS21420 46fefd5956d74acbcbec6a189ddf7f72 293 Gene3D G3DSA:2.40.100.10 110 293 6.0E-38 T 28-03-2018 IPR029000 Cyclophilin-like domain CU254_RS03450 38079af2158f828e04969029ae8deca6 246 Pfam PF14011 EspG family 15 239 1.8E-27 T 28-03-2018 IPR025734 EspG family CU254_RS31380 be931a453b963fa8d525d05a226c2b7a 296 Pfam PF08544 GHMP kinases C terminal 224 265 1.9E-4 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CU254_RS31380 be931a453b963fa8d525d05a226c2b7a 296 Gene3D G3DSA:3.30.230.10 6 173 2.0E-33 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CU254_RS31380 be931a453b963fa8d525d05a226c2b7a 296 PIRSF PIRSF000676 3 293 1.9E-72 T 28-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 CU254_RS31380 be931a453b963fa8d525d05a226c2b7a 296 SUPERFAMILY SSF55060 168 265 6.83E-22 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CU254_RS31380 be931a453b963fa8d525d05a226c2b7a 296 Pfam PF00288 GHMP kinases N terminal domain 86 146 8.4E-11 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CU254_RS31380 be931a453b963fa8d525d05a226c2b7a 296 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 93 104 - T 28-03-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 CU254_RS31380 be931a453b963fa8d525d05a226c2b7a 296 Gene3D G3DSA:3.30.70.890 174 268 2.0E-21 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CU254_RS31380 be931a453b963fa8d525d05a226c2b7a 296 PRINTS PR00958 Homoserine kinase signature 100 115 3.6E-32 T 28-03-2018 CU254_RS31380 be931a453b963fa8d525d05a226c2b7a 296 PRINTS PR00958 Homoserine kinase signature 249 264 3.6E-32 T 28-03-2018 CU254_RS31380 be931a453b963fa8d525d05a226c2b7a 296 PRINTS PR00958 Homoserine kinase signature 14 29 3.6E-32 T 28-03-2018 CU254_RS31380 be931a453b963fa8d525d05a226c2b7a 296 PRINTS PR00958 Homoserine kinase signature 133 146 3.6E-32 T 28-03-2018 CU254_RS31380 be931a453b963fa8d525d05a226c2b7a 296 PRINTS PR00958 Homoserine kinase signature 172 189 3.6E-32 T 28-03-2018 CU254_RS31380 be931a453b963fa8d525d05a226c2b7a 296 Hamap MF_00384 Homoserine kinase [thrB]. 7 293 27.257 T 28-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 CU254_RS31380 be931a453b963fa8d525d05a226c2b7a 296 TIGRFAM TIGR00191 thrB: homoserine kinase 7 265 8.3E-62 T 28-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 CU254_RS31380 be931a453b963fa8d525d05a226c2b7a 296 SUPERFAMILY SSF54211 7 155 2.5E-28 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CU254_RS32405 d39be516ca74678edad3b8c1032a120b 265 SUPERFAMILY SSF89392 31 252 3.06E-12 T 28-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX CU254_RS19085 d871367454caa80b4ecf93d4d47bc0dd 503 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 290 496 2.3E-29 T 28-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CU254_RS19085 d871367454caa80b4ecf93d4d47bc0dd 503 Gene3D G3DSA:2.60.120.260 305 501 1.2E-37 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS19085 d871367454caa80b4ecf93d4d47bc0dd 503 SMART SM00939 271 497 3.8E-44 T 28-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CU254_RS19085 d871367454caa80b4ecf93d4d47bc0dd 503 Gene3D G3DSA:3.40.50.1820 1 304 1.2E-42 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS19085 d871367454caa80b4ecf93d4d47bc0dd 503 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 17 258 8.6E-40 T 28-03-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 CU254_RS19085 d871367454caa80b4ecf93d4d47bc0dd 503 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 9 184 8.6E-50 T 28-03-2018 IPR005674 CocE/Serine esterase GO:0016787 CU254_RS19085 d871367454caa80b4ecf93d4d47bc0dd 503 SUPERFAMILY SSF53474 2 307 2.01E-62 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS19085 d871367454caa80b4ecf93d4d47bc0dd 503 SUPERFAMILY SSF49785 302 502 9.99E-37 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS03940 a0cf07a776ef5990676bb50203d8bf6c 534 Pfam PF00270 DEAD/DEAH box helicase 31 191 1.4E-48 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CU254_RS03940 a0cf07a776ef5990676bb50203d8bf6c 534 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 154 162 - T 28-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site CU254_RS03940 a0cf07a776ef5990676bb50203d8bf6c 534 Pfam PF00271 Helicase conserved C-terminal domain 234 342 1.0E-29 T 28-03-2018 IPR001650 Helicase, C-terminal CU254_RS03940 a0cf07a776ef5990676bb50203d8bf6c 534 Gene3D G3DSA:3.40.50.300 225 528 5.4E-49 T 28-03-2018 CU254_RS03940 a0cf07a776ef5990676bb50203d8bf6c 534 SUPERFAMILY SSF52540 76 360 2.43E-75 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS03940 a0cf07a776ef5990676bb50203d8bf6c 534 SMART SM00490 261 342 1.6E-33 T 28-03-2018 IPR001650 Helicase, C-terminal CU254_RS03940 a0cf07a776ef5990676bb50203d8bf6c 534 Gene3D G3DSA:3.40.50.300 9 224 2.2E-55 T 28-03-2018 CU254_RS03940 a0cf07a776ef5990676bb50203d8bf6c 534 SMART SM00487 25 221 1.4E-53 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CU254_RS08120 8b87d555213ab28f01d2953cd269d1af 419 SUPERFAMILY SSF53383 6 417 1.38E-111 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS08120 8b87d555213ab28f01d2953cd269d1af 419 Gene3D G3DSA:3.40.640.10 175 305 9.1E-35 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS08120 8b87d555213ab28f01d2953cd269d1af 419 Gene3D G3DSA:3.90.1150.10 3 159 1.3E-38 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS08120 8b87d555213ab28f01d2953cd269d1af 419 Pfam PF00202 Aminotransferase class-III 27 415 4.7E-87 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CU254_RS08120 8b87d555213ab28f01d2953cd269d1af 419 Gene3D G3DSA:3.90.1150.10 306 419 5.6E-22 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS08120 8b87d555213ab28f01d2953cd269d1af 419 PIRSF PIRSF000521 122 418 1.0E-25 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CU254_RS08120 8b87d555213ab28f01d2953cd269d1af 419 PIRSF PIRSF000521 25 129 2.6E-4 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CU254_RS08120 8b87d555213ab28f01d2953cd269d1af 419 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 229 266 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CU254_RS06715 ffaec09e1290eaf8db752de74145e44d 261 Pfam PF01012 Electron transfer flavoprotein domain 25 209 7.2E-50 T 28-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CU254_RS06715 ffaec09e1290eaf8db752de74145e44d 261 PIRSF PIRSF000090 2 261 1.8E-84 T 28-03-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 CU254_RS06715 ffaec09e1290eaf8db752de74145e44d 261 Gene3D G3DSA:3.40.50.620 1 256 5.7E-73 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS06715 ffaec09e1290eaf8db752de74145e44d 261 SUPERFAMILY SSF52402 3 255 2.51E-73 T 28-03-2018 CU254_RS06715 ffaec09e1290eaf8db752de74145e44d 261 SMART SM00893 24 214 8.5E-57 T 28-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CU254_RS02480 12df2de5945307b8de840656cebc27a9 518 SUPERFAMILY SSF52317 7 228 6.25E-54 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS02480 12df2de5945307b8de840656cebc27a9 518 Pfam PF00958 GMP synthase C terminal domain 425 517 4.0E-39 T 28-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CU254_RS02480 12df2de5945307b8de840656cebc27a9 518 Gene3D G3DSA:3.40.50.880 4 210 8.2E-46 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS02480 12df2de5945307b8de840656cebc27a9 518 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 8 194 4.9E-69 T 28-03-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CU254_RS02480 12df2de5945307b8de840656cebc27a9 518 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 49 63 6.4E-8 T 28-03-2018 CU254_RS02480 12df2de5945307b8de840656cebc27a9 518 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 8 22 6.4E-8 T 28-03-2018 CU254_RS02480 12df2de5945307b8de840656cebc27a9 518 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 79 95 6.4E-8 T 28-03-2018 CU254_RS02480 12df2de5945307b8de840656cebc27a9 518 Pfam PF00117 Glutamine amidotransferase class-I 10 191 1.3E-40 T 28-03-2018 IPR017926 Glutamine amidotransferase CU254_RS02480 12df2de5945307b8de840656cebc27a9 518 Gene3D G3DSA:3.40.50.620 211 392 1.4E-34 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS02480 12df2de5945307b8de840656cebc27a9 518 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 5 518 52.928 T 28-03-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 CU254_RS02480 12df2de5945307b8de840656cebc27a9 518 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 204 518 3.5E-146 T 28-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CU254_RS02480 12df2de5945307b8de840656cebc27a9 518 Gene3D G3DSA:3.30.300.10 393 518 1.5E-51 T 28-03-2018 CU254_RS02480 12df2de5945307b8de840656cebc27a9 518 Pfam PF02540 NAD synthase 217 250 2.8E-5 T 28-03-2018 IPR022310 NAD/GMP synthase CU254_RS02480 12df2de5945307b8de840656cebc27a9 518 PRINTS PR00096 Glutamine amidotransferase superfamily signature 168 181 1.3E-9 T 28-03-2018 CU254_RS02480 12df2de5945307b8de840656cebc27a9 518 PRINTS PR00096 Glutamine amidotransferase superfamily signature 79 90 1.3E-9 T 28-03-2018 CU254_RS02480 12df2de5945307b8de840656cebc27a9 518 PRINTS PR00096 Glutamine amidotransferase superfamily signature 52 61 1.3E-9 T 28-03-2018 CU254_RS02480 12df2de5945307b8de840656cebc27a9 518 SUPERFAMILY SSF54810 397 518 6.15E-47 T 28-03-2018 CU254_RS02480 12df2de5945307b8de840656cebc27a9 518 PRINTS PR00097 Anthranilate synthase component II signature 168 181 4.5E-7 T 28-03-2018 CU254_RS02480 12df2de5945307b8de840656cebc27a9 518 PRINTS PR00097 Anthranilate synthase component II signature 52 61 4.5E-7 T 28-03-2018 CU254_RS02480 12df2de5945307b8de840656cebc27a9 518 PRINTS PR00097 Anthranilate synthase component II signature 79 90 4.5E-7 T 28-03-2018 CU254_RS02480 12df2de5945307b8de840656cebc27a9 518 SUPERFAMILY SSF52402 184 438 2.09E-55 T 28-03-2018 CU254_RS15735 2e23cee0b68e89e0d434f260fd890c54 216 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 10 142 4.5E-17 T 28-03-2018 IPR010419 Carbon monoxide dehydrogenase subunit G CU254_RS15735 2e23cee0b68e89e0d434f260fd890c54 216 Gene3D G3DSA:3.30.530.20 1 160 1.1E-22 T 28-03-2018 IPR023393 START-like domain CU254_RS15735 2e23cee0b68e89e0d434f260fd890c54 216 SUPERFAMILY SSF55961 1 147 1.28E-28 T 28-03-2018 CU254_RS27285 003be9ded9fdcfd003ffbc1f16497abb 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 4.3E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS27285 003be9ded9fdcfd003ffbc1f16497abb 196 Gene3D G3DSA:1.10.10.60 6 63 4.1E-18 T 28-03-2018 CU254_RS27285 003be9ded9fdcfd003ffbc1f16497abb 196 SUPERFAMILY SSF48498 90 194 1.58E-10 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS27285 003be9ded9fdcfd003ffbc1f16497abb 196 Gene3D G3DSA:1.10.357.10 64 195 5.5E-15 T 28-03-2018 CU254_RS27285 003be9ded9fdcfd003ffbc1f16497abb 196 SUPERFAMILY SSF46689 3 81 8.72E-19 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS27285 003be9ded9fdcfd003ffbc1f16497abb 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 2.7E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS27285 003be9ded9fdcfd003ffbc1f16497abb 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 2.7E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS27285 003be9ded9fdcfd003ffbc1f16497abb 196 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 94 181 1.1E-7 T 28-03-2018 CU254_RS25090 4e6fac9f11b9051c375b65c92e107bea 226 SMART SM00862 151 223 1.2E-28 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS25090 4e6fac9f11b9051c375b65c92e107bea 226 Pfam PF00072 Response regulator receiver domain 9 118 4.7E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS25090 4e6fac9f11b9051c375b65c92e107bea 226 Gene3D G3DSA:1.10.10.10 125 225 3.4E-33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS25090 4e6fac9f11b9051c375b65c92e107bea 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 153 222 9.2E-27 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS25090 4e6fac9f11b9051c375b65c92e107bea 226 SMART SM00448 7 118 5.2E-38 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS25090 4e6fac9f11b9051c375b65c92e107bea 226 SUPERFAMILY SSF46894 126 222 3.4E-28 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS25090 4e6fac9f11b9051c375b65c92e107bea 226 Gene3D G3DSA:3.40.50.2300 3 124 2.8E-33 T 28-03-2018 CU254_RS25090 4e6fac9f11b9051c375b65c92e107bea 226 SUPERFAMILY SSF52172 7 130 4.7E-38 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS27320 65b4c37b0f57649dc555e0edb837311c 491 Gene3D G3DSA:3.90.420.10 161 384 1.2E-51 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CU254_RS27320 65b4c37b0f57649dc555e0edb837311c 491 SUPERFAMILY SSF81296 381 487 3.99E-22 T 28-03-2018 IPR014756 Immunoglobulin E-set CU254_RS27320 65b4c37b0f57649dc555e0edb837311c 491 SUPERFAMILY SSF56524 199 389 1.7E-52 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CU254_RS27320 65b4c37b0f57649dc555e0edb837311c 491 Pfam PF00174 Oxidoreductase molybdopterin binding domain 217 369 1.8E-34 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CU254_RS27320 65b4c37b0f57649dc555e0edb837311c 491 Gene3D G3DSA:2.60.40.650 385 490 2.0E-21 T 28-03-2018 CU254_RS35300 77533cc7e296be4a5df5a406339145a9 255 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 72 231 3.0E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS35300 77533cc7e296be4a5df5a406339145a9 255 SUPERFAMILY SSF161098 52 238 2.62E-25 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS35300 77533cc7e296be4a5df5a406339145a9 255 Gene3D G3DSA:1.10.3720.10 7 249 2.9E-23 T 28-03-2018 CU254_RS32415 94ea97827b689357868c0653f17d5f9e 465 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 5 267 2.0E-75 T 28-03-2018 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CU254_RS32415 94ea97827b689357868c0653f17d5f9e 465 TIGRFAM TIGR02946 acyl_WS_DGAT: acyltransferase, WS/DGAT/MGAT 5 463 1.7E-135 T 28-03-2018 IPR014292 Acyltransferase, WS/DGAT/MGAT GO:0016746|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CU254_RS32415 94ea97827b689357868c0653f17d5f9e 465 SUPERFAMILY SSF52777 32 150 2.89E-5 T 28-03-2018 CU254_RS32415 94ea97827b689357868c0653f17d5f9e 465 Pfam PF06974 Protein of unknown function (DUF1298) 315 461 3.1E-22 T 28-03-2018 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CU254_RS03115 591bae18c2e0fcd7c770603620dfb411 206 Gene3D G3DSA:1.10.1660.10 1 202 1.0E-17 T 28-03-2018 CU254_RS03115 591bae18c2e0fcd7c770603620dfb411 206 Pfam PF13411 MerR HTH family regulatory protein 1 67 1.6E-16 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS03115 591bae18c2e0fcd7c770603620dfb411 206 SUPERFAMILY SSF46955 2 77 3.71E-14 T 28-03-2018 IPR009061 Putative DNA-binding domain CU254_RS03115 591bae18c2e0fcd7c770603620dfb411 206 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 35 55 2.6E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS03115 591bae18c2e0fcd7c770603620dfb411 206 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 11 24 2.6E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS03115 591bae18c2e0fcd7c770603620dfb411 206 SMART SM00422 1 69 5.3E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS06345 cf0ef737bcd22a02916be02232c2b0fe 154 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 17 148 1.5E-39 T 28-03-2018 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|MetaCyc: PWY-7854|Reactome: R-HSA-71032 CU254_RS06345 cf0ef737bcd22a02916be02232c2b0fe 154 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 18 133 4.8E-21 T 28-03-2018 CU254_RS06345 cf0ef737bcd22a02916be02232c2b0fe 154 Gene3D G3DSA:3.10.180.10 10 152 7.7E-31 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS06345 cf0ef737bcd22a02916be02232c2b0fe 154 SUPERFAMILY SSF54593 13 149 2.28E-32 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS07780 1e5cb650bf61dfa54d1f21c8717d8fd9 524 PIRSF PIRSF001363 1 524 1.3E-229 T 28-03-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 CU254_RS07780 1e5cb650bf61dfa54d1f21c8717d8fd9 524 Gene3D G3DSA:1.20.1220.12 410 523 6.6E-39 T 28-03-2018 CU254_RS07780 1e5cb650bf61dfa54d1f21c8717d8fd9 524 SUPERFAMILY SSF51645 12 523 7.06E-178 T 28-03-2018 IPR011076 Malate synthase-like GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 CU254_RS07780 1e5cb650bf61dfa54d1f21c8717d8fd9 524 Pfam PF01274 Malate synthase 6 523 1.6E-190 T 28-03-2018 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 CU254_RS07780 1e5cb650bf61dfa54d1f21c8717d8fd9 524 Gene3D G3DSA:3.20.20.360 76 409 3.3E-112 T 28-03-2018 CU254_RS07780 1e5cb650bf61dfa54d1f21c8717d8fd9 524 ProSitePatterns PS00510 Malate synthase signature. 260 275 - T 28-03-2018 IPR019830 Malate synthase, conserved site GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 CU254_RS07780 1e5cb650bf61dfa54d1f21c8717d8fd9 524 TIGRFAM TIGR01344 malate_syn_A: malate synthase A 17 523 2.6E-232 T 28-03-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 CU254_RS01345 814f0497655919710e9e047b1da77a21 182 SUPERFAMILY SSF56770 9 155 1.44E-66 T 28-03-2018 CU254_RS01345 814f0497655919710e9e047b1da77a21 182 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 1 151 43.095 T 28-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS01345 814f0497655919710e9e047b1da77a21 182 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 11 152 7.2E-70 T 28-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS01345 814f0497655919710e9e047b1da77a21 182 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 38 146 1.8E-23 T 28-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS01345 814f0497655919710e9e047b1da77a21 182 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 118 134 - T 28-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS01345 814f0497655919710e9e047b1da77a21 182 Gene3D G3DSA:3.40.50.700 12 167 8.1E-41 T 28-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS16210 e5091a5716670c4f9d3a803d3e188ef6 691 SMART SM00065 344 491 1.3E-9 T 28-03-2018 IPR003018 GAF domain GO:0005515 CU254_RS16210 e5091a5716670c4f9d3a803d3e188ef6 691 SMART SM00065 178 324 1.7E-21 T 28-03-2018 IPR003018 GAF domain GO:0005515 CU254_RS16210 e5091a5716670c4f9d3a803d3e188ef6 691 Pfam PF13185 GAF domain 343 482 8.7E-10 T 28-03-2018 IPR003018 GAF domain GO:0005515 CU254_RS16210 e5091a5716670c4f9d3a803d3e188ef6 691 Pfam PF13185 GAF domain 178 315 3.8E-20 T 28-03-2018 IPR003018 GAF domain GO:0005515 CU254_RS16210 e5091a5716670c4f9d3a803d3e188ef6 691 Gene3D G3DSA:3.30.450.40 140 333 1.2E-35 T 28-03-2018 IPR029016 GAF domain-like CU254_RS16210 e5091a5716670c4f9d3a803d3e188ef6 691 SUPERFAMILY SSF55781 161 341 6.32E-36 T 28-03-2018 IPR029016 GAF domain-like CU254_RS16210 e5091a5716670c4f9d3a803d3e188ef6 691 SUPERFAMILY SSF55781 326 493 3.27E-22 T 28-03-2018 IPR029016 GAF domain-like CU254_RS16210 e5091a5716670c4f9d3a803d3e188ef6 691 Gene3D G3DSA:3.30.450.40 334 497 8.7E-25 T 28-03-2018 IPR029016 GAF domain-like CU254_RS36245 e6461dfb9c8c78ce3824365e02145945 502 SUPERFAMILY SSF50249 14 154 4.9E-35 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CU254_RS36245 e6461dfb9c8c78ce3824365e02145945 502 Pfam PF01336 OB-fold nucleic acid binding domain 69 145 7.1E-10 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CU254_RS36245 e6461dfb9c8c78ce3824365e02145945 502 Pfam PF00152 tRNA synthetases class II (D, K and N) 162 499 1.1E-69 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CU254_RS36245 e6461dfb9c8c78ce3824365e02145945 502 PRINTS PR00982 Lysyl-tRNA synthetase signature 261 278 8.8E-32 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CU254_RS36245 e6461dfb9c8c78ce3824365e02145945 502 PRINTS PR00982 Lysyl-tRNA synthetase signature 385 401 8.8E-32 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CU254_RS36245 e6461dfb9c8c78ce3824365e02145945 502 PRINTS PR00982 Lysyl-tRNA synthetase signature 243 256 8.8E-32 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CU254_RS36245 e6461dfb9c8c78ce3824365e02145945 502 PRINTS PR00982 Lysyl-tRNA synthetase signature 214 230 8.8E-32 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CU254_RS36245 e6461dfb9c8c78ce3824365e02145945 502 PRINTS PR00982 Lysyl-tRNA synthetase signature 198 208 8.8E-32 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CU254_RS36245 e6461dfb9c8c78ce3824365e02145945 502 Gene3D G3DSA:3.30.930.10 157 499 2.1E-88 T 28-03-2018 CU254_RS36245 e6461dfb9c8c78ce3824365e02145945 502 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 21 502 35.265 T 28-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CU254_RS36245 e6461dfb9c8c78ce3824365e02145945 502 SUPERFAMILY SSF55681 162 500 2.11E-100 T 28-03-2018 CU254_RS36245 e6461dfb9c8c78ce3824365e02145945 502 Gene3D G3DSA:2.40.50.140 15 155 1.3E-38 T 28-03-2018 CU254_RS36245 e6461dfb9c8c78ce3824365e02145945 502 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 16 501 2.8E-141 T 28-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CU254_RS39120 6ad0768e709ea7e9dcf55d0ae89054e3 277 Gene3D G3DSA:3.40.50.150 10 271 3.6E-10 T 28-03-2018 CU254_RS39120 6ad0768e709ea7e9dcf55d0ae89054e3 277 SUPERFAMILY SSF53335 60 265 3.54E-12 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS08135 6ca2953eb756d6c6721196ce94b2d266 112 SUPERFAMILY SSF46785 15 110 1.21E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS08135 6ca2953eb756d6c6721196ce94b2d266 112 Pfam PF01638 HxlR-like helix-turn-helix 26 106 7.4E-10 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type CU254_RS08135 6ca2953eb756d6c6721196ce94b2d266 112 Gene3D G3DSA:1.10.10.10 9 112 2.1E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS33785 e5c17cc08755b9d6d2402efd0fb61c9d 214 SUPERFAMILY SSF51735 1 212 2.63E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS33785 e5c17cc08755b9d6d2402efd0fb61c9d 214 Pfam PF13460 NAD(P)H-binding 8 203 1.1E-18 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS33785 e5c17cc08755b9d6d2402efd0fb61c9d 214 Gene3D G3DSA:3.40.50.720 1 214 5.6E-20 T 28-03-2018 CU254_RS26905 f7cd065d8cc91be09b32848473b129f9 126 Gene3D G3DSA:3.10.180.10 7 126 2.8E-30 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS26905 f7cd065d8cc91be09b32848473b129f9 126 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 122 3.4E-13 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CU254_RS26905 f7cd065d8cc91be09b32848473b129f9 126 SUPERFAMILY SSF54593 1 122 1.48E-28 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS36010 1a6f24eb73900b9bcdd15ed9c1460ebd 223 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 55 7.2E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS36010 1a6f24eb73900b9bcdd15ed9c1460ebd 223 Gene3D G3DSA:1.10.357.10 2 223 3.1E-33 T 28-03-2018 CU254_RS36010 1a6f24eb73900b9bcdd15ed9c1460ebd 223 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 1.1E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS36010 1a6f24eb73900b9bcdd15ed9c1460ebd 223 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 1.1E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS36010 1a6f24eb73900b9bcdd15ed9c1460ebd 223 SUPERFAMILY SSF46689 3 66 1.7E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS36560 af040c33aab96705051a946c66ce6a64 426 PIRSF PIRSF016719 8 426 1.1E-126 T 28-03-2018 IPR008302 Uncharacterised conserved protein UCP016719 CU254_RS36560 af040c33aab96705051a946c66ce6a64 426 Pfam PF07075 Protein of unknown function (DUF1343) 65 425 8.2E-123 T 28-03-2018 IPR008302 Uncharacterised conserved protein UCP016719 CU254_RS01110 c1d5ca5942780145bcfcb6f507c4cfe5 264 Pfam PF12710 haloacid dehalogenase-like hydrolase 16 202 1.3E-25 T 28-03-2018 CU254_RS01110 c1d5ca5942780145bcfcb6f507c4cfe5 264 Gene3D G3DSA:3.40.50.1000 87 240 3.8E-20 T 28-03-2018 IPR023214 HAD-like domain CU254_RS01110 c1d5ca5942780145bcfcb6f507c4cfe5 264 SUPERFAMILY SSF56784 15 233 1.68E-27 T 28-03-2018 IPR023214 HAD-like domain CU254_RS01110 c1d5ca5942780145bcfcb6f507c4cfe5 264 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 16 216 7.4E-55 T 28-03-2018 IPR006385 HAD-superfamily hydrolase, subfamily IB, SerB1-like CU254_RS01110 c1d5ca5942780145bcfcb6f507c4cfe5 264 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 16 204 2.6E-17 T 28-03-2018 CU254_RS28135 facaf372635ac25bbe7860476ae76753 275 Gene3D G3DSA:3.90.226.10 17 232 2.3E-61 T 28-03-2018 CU254_RS28135 facaf372635ac25bbe7860476ae76753 275 Pfam PF00378 Enoyl-CoA hydratase/isomerase 22 274 3.5E-48 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CU254_RS28135 facaf372635ac25bbe7860476ae76753 275 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 115 135 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CU254_RS28135 facaf372635ac25bbe7860476ae76753 275 Gene3D G3DSA:1.10.12.10 233 275 8.6E-9 T 28-03-2018 IPR014748 Crontonase, C-terminal CU254_RS28135 facaf372635ac25bbe7860476ae76753 275 SUPERFAMILY SSF52096 10 275 2.34E-78 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS19920 366a70fd0eb143aae28c0e743a8fb65a 126 Gene3D G3DSA:2.30.110.10 1 124 1.2E-26 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS19920 366a70fd0eb143aae28c0e743a8fb65a 126 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 2 82 3.1E-17 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CU254_RS19920 366a70fd0eb143aae28c0e743a8fb65a 126 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 7 121 2.0E-28 T 28-03-2018 IPR019920 F420-binding domain, putative CU254_RS19920 366a70fd0eb143aae28c0e743a8fb65a 126 SUPERFAMILY SSF50475 2 122 7.2E-30 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS28735 463239c8e4571cffc3208ca5f705ca1e 931 Gene3D G3DSA:1.10.439.10 112 320 3.0E-40 T 28-03-2018 IPR023343 Penicillin amidase type, domain1 GO:0016811 CU254_RS28735 463239c8e4571cffc3208ca5f705ca1e 931 Gene3D G3DSA:3.60.20.10 412 930 1.3E-58 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CU254_RS28735 463239c8e4571cffc3208ca5f705ca1e 931 Pfam PF01804 Penicillin amidase 123 880 2.0E-99 T 28-03-2018 IPR002692 Penicillin/GL-7-ACA/AHL/aculeacin-A acylase GO:0016787|GO:0017000 CU254_RS28735 463239c8e4571cffc3208ca5f705ca1e 931 SUPERFAMILY SSF56235 122 249 4.37E-80 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CU254_RS28735 463239c8e4571cffc3208ca5f705ca1e 931 SUPERFAMILY SSF56235 404 807 4.37E-80 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CU254_RS28735 463239c8e4571cffc3208ca5f705ca1e 931 SUPERFAMILY SSF56235 288 354 4.37E-80 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CU254_RS28735 463239c8e4571cffc3208ca5f705ca1e 931 Gene3D G3DSA:1.10.287.150 321 361 2.6E-8 T 28-03-2018 CU254_RS08405 9f41cc939db4d56c6f656f6c7772ed27 272 SMART SM00020 43 262 2.9E-73 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CU254_RS08405 9f41cc939db4d56c6f656f6c7772ed27 272 SUPERFAMILY SSF50494 18 262 6.78E-67 T 28-03-2018 IPR009003 Peptidase S1, PA clan CU254_RS08405 9f41cc939db4d56c6f656f6c7772ed27 272 Gene3D G3DSA:2.40.10.10 76 136 1.4E-16 T 28-03-2018 CU254_RS08405 9f41cc939db4d56c6f656f6c7772ed27 272 Gene3D G3DSA:2.40.10.10 44 75 6.1E-13 T 28-03-2018 CU254_RS08405 9f41cc939db4d56c6f656f6c7772ed27 272 Pfam PF00089 Trypsin 44 260 2.1E-57 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CU254_RS08405 9f41cc939db4d56c6f656f6c7772ed27 272 Gene3D G3DSA:2.40.10.10 137 268 6.7E-40 T 28-03-2018 CU254_RS08405 9f41cc939db4d56c6f656f6c7772ed27 272 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 217 228 - T 28-03-2018 IPR033116 Serine proteases, trypsin family, serine active site CU254_RS08405 9f41cc939db4d56c6f656f6c7772ed27 272 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 216 228 3.2E-10 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CU254_RS08405 9f41cc939db4d56c6f656f6c7772ed27 272 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 127 141 3.2E-10 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CU254_RS08405 9f41cc939db4d56c6f656f6c7772ed27 272 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 71 86 3.2E-10 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CU254_RS36545 cc1be19639255eafc88b74c42035577f 352 Gene3D G3DSA:3.40.50.300 118 349 1.1E-23 T 28-03-2018 CU254_RS36545 cc1be19639255eafc88b74c42035577f 352 TIGRFAM TIGR03815 CpaE_hom_Actino: helicase/secretion neighborhood CpaE-like protein 15 343 2.7E-87 T 28-03-2018 IPR022521 Conserved hypothetical protein CHP03815, CpaE-like CU254_RS36545 cc1be19639255eafc88b74c42035577f 352 SUPERFAMILY SSF52540 118 315 7.31E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS00740 11334e5660e7119c221bdd845ca4b62c 384 SUPERFAMILY SSF53756 1 371 5.97E-73 T 28-03-2018 CU254_RS00740 11334e5660e7119c221bdd845ca4b62c 384 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 199 371 3.4E-34 T 28-03-2018 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 CU254_RS00740 11334e5660e7119c221bdd845ca4b62c 384 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 249 349 8.9E-11 T 28-03-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 Reactome: R-HSA-156588 CU254_RS00740 11334e5660e7119c221bdd845ca4b62c 384 Gene3D G3DSA:3.40.50.2000 199 357 4.5E-37 T 28-03-2018 CU254_RS00740 11334e5660e7119c221bdd845ca4b62c 384 Gene3D G3DSA:3.40.50.2000 1 194 6.7E-32 T 28-03-2018 CU254_RS09050 afe32056a5ee4e47969255c601c41810 483 Gene3D G3DSA:3.40.50.980 2 144 7.0E-23 T 28-03-2018 CU254_RS09050 afe32056a5ee4e47969255c601c41810 483 Gene3D G3DSA:2.30.38.10 294 378 7.5E-20 T 28-03-2018 CU254_RS09050 afe32056a5ee4e47969255c601c41810 483 Gene3D G3DSA:3.40.50.980 145 293 1.2E-22 T 28-03-2018 CU254_RS09050 afe32056a5ee4e47969255c601c41810 483 Gene3D G3DSA:3.30.300.30 381 482 2.9E-19 T 28-03-2018 CU254_RS09050 afe32056a5ee4e47969255c601c41810 483 Pfam PF13193 AMP-binding enzyme C-terminal domain 395 469 6.4E-14 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS09050 afe32056a5ee4e47969255c601c41810 483 SUPERFAMILY SSF56801 4 479 3.92E-95 T 28-03-2018 CU254_RS09050 afe32056a5ee4e47969255c601c41810 483 Pfam PF00501 AMP-binding enzyme 10 385 2.0E-56 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS16675 d919d69e16afc5892e40351a0a576fea 783 Pfam PF01120 Alpha-L-fucosidase 346 689 4.7E-96 T 28-03-2018 IPR000933 Glycoside hydrolase, family 29 GO:0004560|GO:0005975 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CU254_RS16675 d919d69e16afc5892e40351a0a576fea 783 Gene3D G3DSA:3.20.20.80 343 689 1.6E-101 T 28-03-2018 CU254_RS16675 d919d69e16afc5892e40351a0a576fea 783 Gene3D G3DSA:2.60.40.10 234 340 1.9E-5 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS16675 d919d69e16afc5892e40351a0a576fea 783 Gene3D G3DSA:2.60.40.1180 690 783 2.6E-17 T 28-03-2018 CU254_RS16675 d919d69e16afc5892e40351a0a576fea 783 SMART SM00812 345 733 8.5E-130 T 28-03-2018 IPR000933 Glycoside hydrolase, family 29 GO:0004560|GO:0005975 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CU254_RS16675 d919d69e16afc5892e40351a0a576fea 783 PRINTS PR00741 Glycosyl hydrolase family 29 signature 445 461 4.9E-25 T 28-03-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CU254_RS16675 d919d69e16afc5892e40351a0a576fea 783 PRINTS PR00741 Glycosyl hydrolase family 29 signature 406 421 4.9E-25 T 28-03-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CU254_RS16675 d919d69e16afc5892e40351a0a576fea 783 PRINTS PR00741 Glycosyl hydrolase family 29 signature 642 663 4.9E-25 T 28-03-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CU254_RS16675 d919d69e16afc5892e40351a0a576fea 783 PRINTS PR00741 Glycosyl hydrolase family 29 signature 675 697 4.9E-25 T 28-03-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CU254_RS16675 d919d69e16afc5892e40351a0a576fea 783 PRINTS PR00741 Glycosyl hydrolase family 29 signature 492 511 4.9E-25 T 28-03-2018 IPR016286 Alpha-L-fucosidase, metazoa-type GO:0004560|GO:0006004 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CU254_RS16675 d919d69e16afc5892e40351a0a576fea 783 SUPERFAMILY SSF51445 346 692 2.95E-100 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS33620 7613987c3079e0d398e31eb331817235 419 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 57 406 5.6E-89 T 28-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 CU254_RS33620 7613987c3079e0d398e31eb331817235 419 SUPERFAMILY SSF54909 52 408 1.56E-88 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS33620 7613987c3079e0d398e31eb331817235 419 Pfam PF04261 Dyp-type peroxidase family 57 406 1.8E-103 T 28-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 CU254_RS33620 7613987c3079e0d398e31eb331817235 419 TIGRFAM TIGR01412 tat_substr_1: Tat-translocated enzyme 4 418 2.0E-149 T 28-03-2018 IPR006313 Deferrochelatase/peroxidase EfeB GO:0004601|GO:0015684|GO:0020037|GO:0033212 CU254_RS24260 ed5e2b12e4e1d66102e55ffd1e0b3c8f 324 Pfam PF05726 Pirin C-terminal cupin domain 192 289 2.1E-14 T 28-03-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 CU254_RS24260 ed5e2b12e4e1d66102e55ffd1e0b3c8f 324 Gene3D G3DSA:2.60.120.10 32 266 3.6E-60 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS24260 ed5e2b12e4e1d66102e55ffd1e0b3c8f 324 Pfam PF02678 Pirin 41 140 2.2E-30 T 28-03-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 CU254_RS24260 ed5e2b12e4e1d66102e55ffd1e0b3c8f 324 PIRSF PIRSF006232 20 299 6.7E-75 T 28-03-2018 IPR012093 Pirin Reactome: R-HSA-8935690 CU254_RS24260 ed5e2b12e4e1d66102e55ffd1e0b3c8f 324 SUPERFAMILY SSF51182 38 291 3.46E-67 T 28-03-2018 IPR011051 RmlC-like cupin domain CU254_RS00620 203889dec1b606f01ac85b0f1b757090 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 5.2E-31 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CU254_RS00620 203889dec1b606f01ac85b0f1b757090 67 SMART SM00357 3 67 7.2E-29 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 CU254_RS00620 203889dec1b606f01ac85b0f1b757090 67 PIRSF PIRSF002599 1 67 8.8E-26 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 CU254_RS00620 203889dec1b606f01ac85b0f1b757090 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 28-03-2018 IPR019844 Cold-shock conserved site CU254_RS00620 203889dec1b606f01ac85b0f1b757090 67 Gene3D G3DSA:2.40.50.140 1 67 2.5E-28 T 28-03-2018 CU254_RS00620 203889dec1b606f01ac85b0f1b757090 67 SUPERFAMILY SSF50249 2 66 5.36E-25 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CU254_RS00620 203889dec1b606f01ac85b0f1b757090 67 PRINTS PR00050 Cold shock protein signature 40 58 1.5E-17 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CU254_RS00620 203889dec1b606f01ac85b0f1b757090 67 PRINTS PR00050 Cold shock protein signature 4 19 1.5E-17 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CU254_RS00620 203889dec1b606f01ac85b0f1b757090 67 PRINTS PR00050 Cold shock protein signature 25 34 1.5E-17 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CU254_RS25350 a4b995a13509b9a06679919ad82174cd 426 Gene3D G3DSA:1.20.1250.20 13 212 2.5E-19 T 28-03-2018 CU254_RS25350 a4b995a13509b9a06679919ad82174cd 426 Pfam PF07690 Major Facilitator Superfamily 24 368 1.8E-43 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS25350 a4b995a13509b9a06679919ad82174cd 426 Gene3D G3DSA:1.20.1250.20 213 409 1.3E-23 T 28-03-2018 CU254_RS25350 a4b995a13509b9a06679919ad82174cd 426 SUPERFAMILY SSF103473 5 409 4.58E-57 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS30210 0900e07cb9778be336753694ea31a432 341 Pfam PF13822 Acyl-CoA carboxylase epsilon subunit 285 316 7.8E-8 T 28-03-2018 IPR032716 Acyl-CoA carboxylase epsilon subunit CU254_RS36570 53fce6791d011ca86dbd9e0c0830ce35 295 Gene3D G3DSA:1.10.10.10 1 72 1.2E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS36570 53fce6791d011ca86dbd9e0c0830ce35 295 Gene3D G3DSA:3.40.50.10490 73 275 1.2E-39 T 28-03-2018 CU254_RS36570 53fce6791d011ca86dbd9e0c0830ce35 295 Pfam PF01380 SIS domain 127 254 8.1E-24 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CU254_RS36570 53fce6791d011ca86dbd9e0c0830ce35 295 Pfam PF01418 Helix-turn-helix domain, rpiR family 3 72 8.6E-17 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 CU254_RS36570 53fce6791d011ca86dbd9e0c0830ce35 295 SUPERFAMILY SSF46689 2 71 5.2E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS36570 53fce6791d011ca86dbd9e0c0830ce35 295 SUPERFAMILY SSF53697 95 279 2.23E-43 T 28-03-2018 CU254_RS16480 bcf4bd0c14bdd04bad02fd0d4a09ea59 616 SUPERFAMILY SSF51445 188 232 1.19E-71 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS16480 bcf4bd0c14bdd04bad02fd0d4a09ea59 616 SUPERFAMILY SSF51445 413 490 1.19E-71 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS16480 bcf4bd0c14bdd04bad02fd0d4a09ea59 616 SUPERFAMILY SSF51445 294 378 1.19E-71 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS16480 bcf4bd0c14bdd04bad02fd0d4a09ea59 616 SUPERFAMILY SSF51445 53 147 1.19E-71 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS16480 bcf4bd0c14bdd04bad02fd0d4a09ea59 616 Pfam PF00754 F5/8 type C domain 503 597 8.2E-8 T 28-03-2018 IPR000421 Coagulation factor 5/8 C-terminal domain CU254_RS16480 bcf4bd0c14bdd04bad02fd0d4a09ea59 616 Pfam PF01120 Alpha-L-fucosidase 92 487 2.1E-28 T 28-03-2018 IPR000933 Glycoside hydrolase, family 29 GO:0004560|GO:0005975 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CU254_RS16480 bcf4bd0c14bdd04bad02fd0d4a09ea59 616 SUPERFAMILY SSF49785 503 605 5.87E-7 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS16480 bcf4bd0c14bdd04bad02fd0d4a09ea59 616 Gene3D G3DSA:2.60.120.260 495 612 3.0E-14 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS16480 bcf4bd0c14bdd04bad02fd0d4a09ea59 616 Gene3D G3DSA:3.20.20.80 42 494 8.3E-91 T 28-03-2018 CU254_RS16480 bcf4bd0c14bdd04bad02fd0d4a09ea59 616 SMART SM00812 54 507 1.7E-11 T 28-03-2018 IPR000933 Glycoside hydrolase, family 29 GO:0004560|GO:0005975 KEGG: 00511+3.2.1.51|Reactome: R-HSA-6798695 CU254_RS41030 fefd6c02874389b9fd2bd15b4237ca15 291 Gene3D G3DSA:2.60.120.10 53 193 4.4E-5 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS41030 fefd6c02874389b9fd2bd15b4237ca15 291 SUPERFAMILY SSF51182 114 190 2.18E-6 T 28-03-2018 IPR011051 RmlC-like cupin domain CU254_RS35450 e5d94af53b0c16edf3fd04a0c7d20df1 220 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 124 213 2.8E-12 T 28-03-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain CU254_RS36930 2e00d8d60cd99dc0f6bc2502682df33c 346 Gene3D G3DSA:3.30.360.10 142 326 2.4E-67 T 28-03-2018 CU254_RS36930 2e00d8d60cd99dc0f6bc2502682df33c 346 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 4 343 36.378 T 28-03-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CU254_RS36930 2e00d8d60cd99dc0f6bc2502682df33c 346 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 140 329 1.7E-50 T 28-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CU254_RS36930 2e00d8d60cd99dc0f6bc2502682df33c 346 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 6 344 5.7E-139 T 28-03-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CU254_RS36930 2e00d8d60cd99dc0f6bc2502682df33c 346 PIRSF PIRSF000148 4 346 2.5E-114 T 28-03-2018 CU254_RS36930 2e00d8d60cd99dc0f6bc2502682df33c 346 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 244 258 - T 28-03-2018 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CU254_RS36930 2e00d8d60cd99dc0f6bc2502682df33c 346 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 6 120 1.9E-32 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CU254_RS36930 2e00d8d60cd99dc0f6bc2502682df33c 346 SMART SM00859 6 121 1.2E-41 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CU254_RS36930 2e00d8d60cd99dc0f6bc2502682df33c 346 Gene3D G3DSA:3.40.50.720 1 141 2.4E-38 T 28-03-2018 CU254_RS36930 2e00d8d60cd99dc0f6bc2502682df33c 346 SUPERFAMILY SSF55347 130 330 2.04E-60 T 28-03-2018 CU254_RS36930 2e00d8d60cd99dc0f6bc2502682df33c 346 SUPERFAMILY SSF51735 5 157 1.92E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS11700 75197d78ff885ab0b13e2fed9ea616f2 377 Pfam PF07730 Histidine kinase 178 240 3.1E-16 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CU254_RS11700 75197d78ff885ab0b13e2fed9ea616f2 377 Gene3D G3DSA:3.30.565.10 250 377 2.0E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS11700 75197d78ff885ab0b13e2fed9ea616f2 377 SUPERFAMILY SSF55874 275 371 8.1E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS03400 96a5df4f4618ed26738ee55c052b3591 189 Gene3D G3DSA:3.30.70.270 42 96 6.7E-4 T 28-03-2018 CU254_RS34385 a5a9d0a493854512d526c44939d519ca 437 Gene3D G3DSA:1.20.1250.20 233 437 1.6E-22 T 28-03-2018 CU254_RS34385 a5a9d0a493854512d526c44939d519ca 437 Gene3D G3DSA:1.20.1250.20 9 219 2.4E-35 T 28-03-2018 CU254_RS34385 a5a9d0a493854512d526c44939d519ca 437 Pfam PF07690 Major Facilitator Superfamily 24 394 6.0E-46 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS34385 a5a9d0a493854512d526c44939d519ca 437 SUPERFAMILY SSF103473 11 433 1.05E-82 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS19070 ff2e2e9927dd26b8320993e2d7c7fbec 258 Pfam PF08237 PE-PPE domain 60 202 7.3E-14 T 28-03-2018 IPR013228 PE-PPE, C-terminal CU254_RS19070 ff2e2e9927dd26b8320993e2d7c7fbec 258 SUPERFAMILY SSF53474 53 218 2.93E-15 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS19070 ff2e2e9927dd26b8320993e2d7c7fbec 258 Gene3D G3DSA:3.40.50.1820 12 235 6.4E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS18955 a1775f4600505d1815f53effede55e3f 364 Pfam PF01872 RibD C-terminal domain 164 343 4.6E-20 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CU254_RS18955 a1775f4600505d1815f53effede55e3f 364 Gene3D G3DSA:3.30.530.20 1 163 4.9E-31 T 28-03-2018 IPR023393 START-like domain CU254_RS18955 a1775f4600505d1815f53effede55e3f 364 Gene3D G3DSA:3.40.430.10 164 363 6.7E-36 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CU254_RS18955 a1775f4600505d1815f53effede55e3f 364 SUPERFAMILY SSF53597 164 350 1.31E-25 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CU254_RS18955 a1775f4600505d1815f53effede55e3f 364 SUPERFAMILY SSF55961 11 154 1.81E-43 T 28-03-2018 CU254_RS18955 a1775f4600505d1815f53effede55e3f 364 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 22 153 8.1E-22 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CU254_RS15850 cece16db69ba5e471c065613dd44638a 228 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 127 155 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS15850 cece16db69ba5e471c065613dd44638a 228 Pfam PF00106 short chain dehydrogenase 7 183 1.8E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS15850 cece16db69ba5e471c065613dd44638a 228 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 2.4E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS15850 cece16db69ba5e471c065613dd44638a 228 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 177 2.4E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS15850 cece16db69ba5e471c065613dd44638a 228 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 114 130 2.4E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS15850 cece16db69ba5e471c065613dd44638a 228 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 159 2.4E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS15850 cece16db69ba5e471c065613dd44638a 228 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 188 208 2.4E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS15850 cece16db69ba5e471c065613dd44638a 228 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 68 79 2.4E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS15850 cece16db69ba5e471c065613dd44638a 228 Gene3D G3DSA:3.40.50.720 5 216 3.6E-49 T 28-03-2018 CU254_RS15850 cece16db69ba5e471c065613dd44638a 228 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 176 0.0025 T 28-03-2018 CU254_RS15850 cece16db69ba5e471c065613dd44638a 228 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 120 128 1.9E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS15850 cece16db69ba5e471c065613dd44638a 228 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 68 79 1.9E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS15850 cece16db69ba5e471c065613dd44638a 228 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 159 1.9E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS15850 cece16db69ba5e471c065613dd44638a 228 SUPERFAMILY SSF51735 6 210 1.9E-51 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS20030 b37d8d123bd5786d939d9af55377c3c3 538 SMART SM00382 302 492 1.7E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS20030 b37d8d123bd5786d939d9af55377c3c3 538 SMART SM00382 30 227 1.7E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS20030 b37d8d123bd5786d939d9af55377c3c3 538 SUPERFAMILY SSF52540 272 514 4.65E-71 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS20030 b37d8d123bd5786d939d9af55377c3c3 538 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS20030 b37d8d123bd5786d939d9af55377c3c3 538 Gene3D G3DSA:3.40.50.300 2 264 7.9E-69 T 28-03-2018 CU254_RS20030 b37d8d123bd5786d939d9af55377c3c3 538 Gene3D G3DSA:3.40.50.300 268 535 7.0E-75 T 28-03-2018 CU254_RS20030 b37d8d123bd5786d939d9af55377c3c3 538 Pfam PF00005 ABC transporter 294 443 1.2E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS20030 b37d8d123bd5786d939d9af55377c3c3 538 Pfam PF00005 ABC transporter 22 177 2.5E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS20030 b37d8d123bd5786d939d9af55377c3c3 538 SUPERFAMILY SSF52540 5 249 6.79E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS20030 b37d8d123bd5786d939d9af55377c3c3 538 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 494 526 0.0044 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CU254_RS20030 b37d8d123bd5786d939d9af55377c3c3 538 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 229 261 0.11 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CU254_RS20030 b37d8d123bd5786d939d9af55377c3c3 538 ProSitePatterns PS00211 ABC transporters family signature. 415 429 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS26135 634decea2e10e618dcf7894f68033b55 393 SUPERFAMILY SSF56059 79 316 1.36E-30 T 28-03-2018 CU254_RS26135 634decea2e10e618dcf7894f68033b55 393 Gene3D G3DSA:3.30.470.20 103 388 8.2E-28 T 28-03-2018 CU254_RS26135 634decea2e10e618dcf7894f68033b55 393 Gene3D G3DSA:3.40.50.20 9 102 4.5E-6 T 28-03-2018 CU254_RS26135 634decea2e10e618dcf7894f68033b55 393 Pfam PF13535 ATP-grasp domain 134 276 1.4E-6 T 28-03-2018 CU254_RS38390 c77689d5db05f99f25aa0257fb9e29ed 193 Pfam PF00692 dUTPase 70 176 3.3E-9 T 28-03-2018 IPR029054 dUTPase-like CU254_RS38390 c77689d5db05f99f25aa0257fb9e29ed 193 Hamap MF_00146 dCTP deaminase [dcd]. 1 182 33.866 T 28-03-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 CU254_RS38390 c77689d5db05f99f25aa0257fb9e29ed 193 Gene3D G3DSA:2.70.40.10 1 159 4.1E-47 T 28-03-2018 CU254_RS38390 c77689d5db05f99f25aa0257fb9e29ed 193 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 3 181 2.3E-63 T 28-03-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 CU254_RS38390 c77689d5db05f99f25aa0257fb9e29ed 193 SUPERFAMILY SSF51283 2 184 9.16E-56 T 28-03-2018 IPR029054 dUTPase-like CU254_RS01755 b082fe5a72c9619d5c3103967d151000 130 Gene3D G3DSA:1.20.5.710 4 58 5.1E-13 T 28-03-2018 CU254_RS01755 b082fe5a72c9619d5c3103967d151000 130 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 64 104 2.0E-13 T 28-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS01755 b082fe5a72c9619d5c3103967d151000 130 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 3 130 23.553 T 28-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS01755 b082fe5a72c9619d5c3103967d151000 130 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 63 130 6.6E-27 T 28-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS01755 b082fe5a72c9619d5c3103967d151000 130 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 6 53 3.9E-17 T 28-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS01755 b082fe5a72c9619d5c3103967d151000 130 Gene3D G3DSA:3.30.1390.10 59 130 1.6E-27 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CU254_RS01755 b082fe5a72c9619d5c3103967d151000 130 SUPERFAMILY SSF48300 5 65 2.22E-13 T 28-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS01755 b082fe5a72c9619d5c3103967d151000 130 SUPERFAMILY SSF54736 59 130 4.88E-21 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CU254_RS01755 b082fe5a72c9619d5c3103967d151000 130 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 130 7.1E-46 T 28-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS08315 13358664462927d211a03aab4823dbcd 377 Pfam PF04551 GcpE protein 15 355 7.0E-136 T 28-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CU254_RS08315 13358664462927d211a03aab4823dbcd 377 SUPERFAMILY SSF51717 40 213 1.41E-10 T 28-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CU254_RS08315 13358664462927d211a03aab4823dbcd 377 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 10 361 33.821 T 28-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CU254_RS08315 13358664462927d211a03aab4823dbcd 377 PIRSF PIRSF004640 6 366 5.2E-146 T 28-03-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CU254_RS08315 13358664462927d211a03aab4823dbcd 377 SUPERFAMILY SSF56014 270 355 1.05E-10 T 28-03-2018 CU254_RS08315 13358664462927d211a03aab4823dbcd 377 Gene3D G3DSA:3.20.20.120 23 151 6.8E-19 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CU254_RS08315 13358664462927d211a03aab4823dbcd 377 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 12 354 2.8E-130 T 28-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CU254_RS40605 10a218f2589a954745d3e374bec75b49 232 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 74 7.0E-20 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS40605 10a218f2589a954745d3e374bec75b49 232 Gene3D G3DSA:1.10.10.10 4 76 3.8E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS40605 10a218f2589a954745d3e374bec75b49 232 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 3.8E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS40605 10a218f2589a954745d3e374bec75b49 232 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 3.8E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS40605 10a218f2589a954745d3e374bec75b49 232 Gene3D G3DSA:1.20.120.530 91 232 2.2E-27 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS40605 10a218f2589a954745d3e374bec75b49 232 Pfam PF07729 FCD domain 98 219 3.4E-25 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS40605 10a218f2589a954745d3e374bec75b49 232 SUPERFAMILY SSF46785 11 78 1.66E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS40605 10a218f2589a954745d3e374bec75b49 232 SUPERFAMILY SSF48008 96 225 4.45E-26 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS40605 10a218f2589a954745d3e374bec75b49 232 SMART SM00345 15 74 2.4E-21 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS40605 10a218f2589a954745d3e374bec75b49 232 SMART SM00895 97 221 9.1E-17 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS33820 4568fbdd1b9ea3c9996f7b3e875fa5f0 322 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 9 299 30.715 T 28-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CU254_RS33820 4568fbdd1b9ea3c9996f7b3e875fa5f0 322 Gene3D G3DSA:3.30.230.10 9 170 2.6E-46 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CU254_RS33820 4568fbdd1b9ea3c9996f7b3e875fa5f0 322 PIRSF PIRSF010376 8 307 6.3E-78 T 28-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CU254_RS33820 4568fbdd1b9ea3c9996f7b3e875fa5f0 322 Pfam PF08544 GHMP kinases C terminal 214 286 6.0E-9 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CU254_RS33820 4568fbdd1b9ea3c9996f7b3e875fa5f0 322 SUPERFAMILY SSF55060 175 294 3.74E-23 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CU254_RS33820 4568fbdd1b9ea3c9996f7b3e875fa5f0 322 Pfam PF00288 GHMP kinases N terminal domain 97 155 9.9E-9 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CU254_RS33820 4568fbdd1b9ea3c9996f7b3e875fa5f0 322 SUPERFAMILY SSF54211 8 168 3.42E-42 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CU254_RS33820 4568fbdd1b9ea3c9996f7b3e875fa5f0 322 Gene3D G3DSA:3.30.70.890 172 301 3.4E-31 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CU254_RS33820 4568fbdd1b9ea3c9996f7b3e875fa5f0 322 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 10 281 2.8E-50 T 28-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CU254_RS14080 08ae7dfe060616a6992fae2b2cebc251 285 Pfam PF00296 Luciferase-like monooxygenase 1 233 1.2E-40 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS14080 08ae7dfe060616a6992fae2b2cebc251 285 Gene3D G3DSA:3.20.20.30 1 282 2.9E-56 T 28-03-2018 CU254_RS14080 08ae7dfe060616a6992fae2b2cebc251 285 SUPERFAMILY SSF51679 1 255 6.02E-50 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS14095 57608179aa008a29e494b72c6096a867 341 Pfam PF00356 Bacterial regulatory proteins, lacI family 9 54 1.0E-17 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CU254_RS14095 57608179aa008a29e494b72c6096a867 341 Gene3D G3DSA:3.40.50.2300 182 341 2.5E-25 T 28-03-2018 CU254_RS14095 57608179aa008a29e494b72c6096a867 341 Pfam PF13377 Periplasmic binding protein-like domain 179 339 1.7E-22 T 28-03-2018 CU254_RS14095 57608179aa008a29e494b72c6096a867 341 SMART SM00354 7 77 4.3E-27 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CU254_RS14095 57608179aa008a29e494b72c6096a867 341 Gene3D G3DSA:3.40.50.2300 61 181 1.1E-10 T 28-03-2018 CU254_RS14095 57608179aa008a29e494b72c6096a867 341 Gene3D G3DSA:1.10.10.60 3 22 8.6E-5 T 28-03-2018 CU254_RS14095 57608179aa008a29e494b72c6096a867 341 SUPERFAMILY SSF47413 7 64 1.37E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS14095 57608179aa008a29e494b72c6096a867 341 Gene3D G3DSA:1.10.260.40 23 60 1.5E-23 T 28-03-2018 CU254_RS14095 57608179aa008a29e494b72c6096a867 341 SUPERFAMILY SSF53822 88 340 2.14E-24 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CU254_RS00845 bcadd8dbe9c003fbdf2e551c1a8bb4f5 467 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 78 3.1E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS00845 bcadd8dbe9c003fbdf2e551c1a8bb4f5 467 Gene3D G3DSA:3.90.1150.10 337 456 6.1E-24 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS00845 bcadd8dbe9c003fbdf2e551c1a8bb4f5 467 Pfam PF00155 Aminotransferase class I and II 129 446 1.7E-25 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CU254_RS00845 bcadd8dbe9c003fbdf2e551c1a8bb4f5 467 Gene3D G3DSA:1.10.10.10 6 81 1.2E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS00845 bcadd8dbe9c003fbdf2e551c1a8bb4f5 467 SUPERFAMILY SSF53383 90 447 7.56E-75 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS00845 bcadd8dbe9c003fbdf2e551c1a8bb4f5 467 SUPERFAMILY SSF46785 19 83 1.13E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS00845 bcadd8dbe9c003fbdf2e551c1a8bb4f5 467 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 39 53 3.7E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS00845 bcadd8dbe9c003fbdf2e551c1a8bb4f5 467 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 53 69 3.7E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS00845 bcadd8dbe9c003fbdf2e551c1a8bb4f5 467 Gene3D G3DSA:3.40.640.10 129 336 1.2E-36 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS00845 bcadd8dbe9c003fbdf2e551c1a8bb4f5 467 SMART SM00345 20 79 4.1E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS11110 80144c4964f7c2deb4baacedb2054732 309 Gene3D G3DSA:1.10.10.10 19 255 0.0013 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS11110 80144c4964f7c2deb4baacedb2054732 309 TIGRFAM TIGR04222 near_uncomplex: TIGR04222 domain 16 251 1.6E-49 T 28-03-2018 IPR026467 Ser/Gly rich, Cys interspersed, C-terminal domain CU254_RS04785 124fc1215fe6796f99b277e47a55e96e 312 Gene3D G3DSA:3.40.50.720 199 298 0.0038 T 28-03-2018 CU254_RS27685 162715794644140441d9d5b17172dec7 220 SUPERFAMILY SSF52266 2 215 2.75E-28 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CU254_RS27685 162715794644140441d9d5b17172dec7 220 Gene3D G3DSA:3.40.50.1110 2 217 5.8E-25 T 28-03-2018 CU254_RS27685 162715794644140441d9d5b17172dec7 220 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 6 198 2.0E-17 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CU254_RS27345 706d726a09776af6b88e94e1727423fb 329 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 20 321 2.2E-77 T 28-03-2018 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 CU254_RS27345 706d726a09776af6b88e94e1727423fb 329 SUPERFAMILY SSF51556 276 324 5.82E-79 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS27345 706d726a09776af6b88e94e1727423fb 329 SUPERFAMILY SSF51556 11 249 5.82E-79 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS27345 706d726a09776af6b88e94e1727423fb 329 Gene3D G3DSA:3.20.20.140 5 325 1.8E-75 T 28-03-2018 CU254_RS04380 8c400ed60029fe487ce023ac256db33b 358 SUPERFAMILY SSF52540 23 259 2.1E-86 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS04380 8c400ed60029fe487ce023ac256db33b 358 SUPERFAMILY SSF50331 249 351 1.25E-7 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CU254_RS04380 8c400ed60029fe487ce023ac256db33b 358 Gene3D G3DSA:2.40.50.140 277 353 0.002 T 28-03-2018 CU254_RS04380 8c400ed60029fe487ce023ac256db33b 358 SMART SM00382 47 230 1.1E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS04380 8c400ed60029fe487ce023ac256db33b 358 Pfam PF00005 ABC transporter 39 180 3.2E-36 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS04380 8c400ed60029fe487ce023ac256db33b 358 Pfam PF08402 TOBE domain 275 350 2.6E-15 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CU254_RS04380 8c400ed60029fe487ce023ac256db33b 358 Gene3D G3DSA:3.40.50.300 19 273 3.6E-75 T 28-03-2018 CU254_RS04380 8c400ed60029fe487ce023ac256db33b 358 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS21240 3026a57291165318b72b9d4066698d79 113 Gene3D G3DSA:3.30.1460.30 3 100 1.4E-4 T 28-03-2018 CU254_RS21240 3026a57291165318b72b9d4066698d79 113 SUPERFAMILY SSF142906 9 102 1.12E-7 T 28-03-2018 CU254_RS21240 3026a57291165318b72b9d4066698d79 113 Pfam PF04237 YjbR 22 98 2.6E-10 T 28-03-2018 IPR007351 Uncharacterised protein YjbR CU254_RS32680 2b999745c5aa5fad80a65eccb2c6954d 441 PRINTS PR00344 Bacterial sensor protein C-terminal signature 399 417 2.1E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS32680 2b999745c5aa5fad80a65eccb2c6954d 441 PRINTS PR00344 Bacterial sensor protein C-terminal signature 382 392 2.1E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS32680 2b999745c5aa5fad80a65eccb2c6954d 441 PRINTS PR00344 Bacterial sensor protein C-terminal signature 364 378 2.1E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS32680 2b999745c5aa5fad80a65eccb2c6954d 441 Gene3D G3DSA:1.10.287.130 213 284 5.1E-12 T 28-03-2018 CU254_RS32680 2b999745c5aa5fad80a65eccb2c6954d 441 SUPERFAMILY SSF47384 206 289 1.65E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS32680 2b999745c5aa5fad80a65eccb2c6954d 441 SMART SM00388 223 288 1.5E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS32680 2b999745c5aa5fad80a65eccb2c6954d 441 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 335 435 6.6E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS32680 2b999745c5aa5fad80a65eccb2c6954d 441 SMART SM00387 329 439 3.4E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS32680 2b999745c5aa5fad80a65eccb2c6954d 441 Pfam PF00512 His Kinase A (phospho-acceptor) domain 224 288 1.7E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS32680 2b999745c5aa5fad80a65eccb2c6954d 441 Gene3D G3DSA:3.30.565.10 288 441 2.2E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS32680 2b999745c5aa5fad80a65eccb2c6954d 441 SUPERFAMILY SSF55874 295 437 2.36E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS16455 030b2574a7009422770e167a81782ae3 321 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 320 2.9E-39 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS16455 030b2574a7009422770e167a81782ae3 321 SUPERFAMILY SSF161098 94 308 2.22E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS16455 030b2574a7009422770e167a81782ae3 321 Gene3D G3DSA:1.10.3720.10 1 309 1.3E-33 T 28-03-2018 CU254_RS20020 e186e2e84cecd4beb5f8fedc0aa66f8c 314 SUPERFAMILY SSF53474 3 311 7.84E-55 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS20020 e186e2e84cecd4beb5f8fedc0aa66f8c 314 PIRSF PIRSF006431 2 314 3.3E-103 T 28-03-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 CU254_RS20020 e186e2e84cecd4beb5f8fedc0aa66f8c 314 Gene3D G3DSA:3.40.50.1820 7 314 3.4E-55 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS20020 e186e2e84cecd4beb5f8fedc0aa66f8c 314 PRINTS PR00111 Alpha/beta hydrolase fold signature 107 120 9.0E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS20020 e186e2e84cecd4beb5f8fedc0aa66f8c 314 PRINTS PR00111 Alpha/beta hydrolase fold signature 121 134 9.0E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS20020 e186e2e84cecd4beb5f8fedc0aa66f8c 314 PRINTS PR00111 Alpha/beta hydrolase fold signature 56 71 9.0E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS20020 e186e2e84cecd4beb5f8fedc0aa66f8c 314 Pfam PF00561 alpha/beta hydrolase fold 31 295 5.0E-35 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS20020 e186e2e84cecd4beb5f8fedc0aa66f8c 314 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 59 70 2.7E-13 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CU254_RS20020 e186e2e84cecd4beb5f8fedc0aa66f8c 314 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 107 121 2.7E-13 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CU254_RS20020 e186e2e84cecd4beb5f8fedc0aa66f8c 314 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 33 41 2.7E-13 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CU254_RS20020 e186e2e84cecd4beb5f8fedc0aa66f8c 314 TIGRFAM TIGR01249 pro_imino_pep_1: prolyl aminopeptidase 7 303 1.1E-83 T 28-03-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 CU254_RS23960 0861a11a82fab2c851574fb5d21d4ffb 203 Gene3D G3DSA:1.10.10.60 1 41 2.9E-15 T 28-03-2018 CU254_RS23960 0861a11a82fab2c851574fb5d21d4ffb 203 SUPERFAMILY SSF46689 10 91 2.15E-20 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS23960 0861a11a82fab2c851574fb5d21d4ffb 203 Gene3D G3DSA:1.10.357.10 70 203 4.1E-20 T 28-03-2018 CU254_RS23960 0861a11a82fab2c851574fb5d21d4ffb 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 3.1E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS23960 0861a11a82fab2c851574fb5d21d4ffb 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 3.1E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS23960 0861a11a82fab2c851574fb5d21d4ffb 203 SUPERFAMILY SSF48498 87 202 3.71E-14 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS23960 0861a11a82fab2c851574fb5d21d4ffb 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 66 3.5E-18 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS23960 0861a11a82fab2c851574fb5d21d4ffb 203 Gene3D G3DSA:1.10.260.40 42 69 2.6E-13 T 28-03-2018 CU254_RS00245 8c06b276e1c23810c0679055b027f8ba 110 Gene3D G3DSA:1.10.287.1060 5 102 9.9E-5 T 28-03-2018 CU254_RS32195 0c00f9c78af6eeafffcf649d235e160e 371 SUPERFAMILY SSF51735 137 303 2.51E-48 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS32195 0c00f9c78af6eeafffcf649d235e160e 371 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 2 370 1.8E-171 T 28-03-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 CU254_RS32195 0c00f9c78af6eeafffcf649d235e160e 371 SMART SM01003 4 137 6.4E-76 T 28-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CU254_RS32195 0c00f9c78af6eeafffcf649d235e160e 371 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 5 137 1.1E-46 T 28-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CU254_RS32195 0c00f9c78af6eeafffcf649d235e160e 371 SMART SM01002 149 297 3.0E-85 T 28-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CU254_RS32195 0c00f9c78af6eeafffcf649d235e160e 371 Gene3D G3DSA:3.40.50.720 1 192 1.2E-45 T 28-03-2018 CU254_RS32195 0c00f9c78af6eeafffcf649d235e160e 371 Gene3D G3DSA:3.40.50.720 193 371 2.5E-43 T 28-03-2018 CU254_RS32195 0c00f9c78af6eeafffcf649d235e160e 371 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 141 352 2.9E-82 T 28-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CU254_RS32195 0c00f9c78af6eeafffcf649d235e160e 371 PIRSF PIRSF000183 1 371 3.7E-167 T 28-03-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 CU254_RS32195 0c00f9c78af6eeafffcf649d235e160e 371 SUPERFAMILY SSF52283 305 359 7.48E-66 T 28-03-2018 CU254_RS32195 0c00f9c78af6eeafffcf649d235e160e 371 SUPERFAMILY SSF52283 2 137 7.48E-66 T 28-03-2018 CU254_RS15700 115f366370fec339aca6d98951b1d1d0 469 Gene3D G3DSA:3.30.1540.10 100 194 4.8E-11 T 28-03-2018 CU254_RS15700 115f366370fec339aca6d98951b1d1d0 469 SUPERFAMILY SSF89796 26 200 6.8E-24 T 28-03-2018 IPR023606 CoA-transferase family III domain CU254_RS15700 115f366370fec339aca6d98951b1d1d0 469 Pfam PF02515 CoA-transferase family III 215 411 4.5E-45 T 28-03-2018 IPR003673 CoA-transferase family III GO:0003824 CU254_RS15700 115f366370fec339aca6d98951b1d1d0 469 Gene3D G3DSA:3.40.50.10540 210 427 9.6E-65 T 28-03-2018 IPR023606 CoA-transferase family III domain CU254_RS15700 115f366370fec339aca6d98951b1d1d0 469 SUPERFAMILY SSF89796 213 465 2.35E-57 T 28-03-2018 IPR023606 CoA-transferase family III domain CU254_RS03605 2df55e9db1ef304721143edbb73f5004 362 SUPERFAMILY SSF53383 3 361 3.03E-82 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS03605 2df55e9db1ef304721143edbb73f5004 362 Gene3D G3DSA:3.40.640.10 33 265 1.4E-39 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS03605 2df55e9db1ef304721143edbb73f5004 362 TIGRFAM TIGR03539 DapC_actino: succinyldiaminopimelate transaminase 4 359 6.1E-181 T 28-03-2018 IPR019880 Succinyldiaminopimelate transaminase, DapC, actinobacteria CU254_RS03605 2df55e9db1ef304721143edbb73f5004 362 Gene3D G3DSA:3.90.1150.10 266 362 1.2E-24 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS03605 2df55e9db1ef304721143edbb73f5004 362 Pfam PF00155 Aminotransferase class I and II 26 359 2.2E-49 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CU254_RS17780 934304340f84eeb2a315ebfc4fb701ae 748 Pfam PF09971 Predicted membrane protein (DUF2206) 503 747 1.8E-11 T 28-03-2018 IPR018701 Protein of unknown function DUF2206, membrane CU254_RS17780 934304340f84eeb2a315ebfc4fb701ae 748 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 259 369 2.6E-7 T 28-03-2018 CU254_RS24770 5c41ba82ea945cf622ee3ec17f0c6aa8 847 Gene3D G3DSA:1.10.10.10 757 811 2.6E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS24770 5c41ba82ea945cf622ee3ec17f0c6aa8 847 Pfam PF13491 4TM region of DNA translocase FtsK/SpoIIIE 121 242 4.9E-8 T 28-03-2018 IPR025199 DNA translocase FtsK, 4TM region CU254_RS24770 5c41ba82ea945cf622ee3ec17f0c6aa8 847 Gene3D G3DSA:3.40.50.300 334 696 1.9E-44 T 28-03-2018 CU254_RS24770 5c41ba82ea945cf622ee3ec17f0c6aa8 847 Pfam PF01580 FtsK/SpoIIIE family 455 655 7.7E-61 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CU254_RS24770 5c41ba82ea945cf622ee3ec17f0c6aa8 847 Pfam PF09397 Ftsk gamma domain 761 817 1.3E-21 T 28-03-2018 IPR018541 FtsK gamma domain CU254_RS24770 5c41ba82ea945cf622ee3ec17f0c6aa8 847 SUPERFAMILY SSF52540 429 727 3.49E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS24770 5c41ba82ea945cf622ee3ec17f0c6aa8 847 SUPERFAMILY SSF46785 757 822 1.77E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS24770 5c41ba82ea945cf622ee3ec17f0c6aa8 847 SMART SM00843 756 820 3.2E-29 T 28-03-2018 IPR018541 FtsK gamma domain CU254_RS20615 d7a226c4c109a2fb671ccbb88bdc24eb 205 Gene3D G3DSA:3.40.50.300 1 177 4.1E-22 T 28-03-2018 CU254_RS20615 d7a226c4c109a2fb671ccbb88bdc24eb 205 Pfam PF00005 ABC transporter 3 141 1.9E-10 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS20615 d7a226c4c109a2fb671ccbb88bdc24eb 205 SUPERFAMILY SSF52540 2 176 5.44E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS03135 67d44f8888fb896e4b9dc0de0a7d9081 330 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 17 322 1.0E-116 T 28-03-2018 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CU254_RS03135 67d44f8888fb896e4b9dc0de0a7d9081 330 Gene3D G3DSA:1.10.287.130 264 325 3.4E-25 T 28-03-2018 CU254_RS03135 67d44f8888fb896e4b9dc0de0a7d9081 330 Gene3D G3DSA:3.40.50.300 52 262 2.5E-36 T 28-03-2018 CU254_RS03135 67d44f8888fb896e4b9dc0de0a7d9081 330 SUPERFAMILY SSF52540 4 325 2.11E-96 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS03135 67d44f8888fb896e4b9dc0de0a7d9081 330 Gene3D G3DSA:1.20.5.170 2 51 1.1E-20 T 28-03-2018 CU254_RS03135 67d44f8888fb896e4b9dc0de0a7d9081 330 Pfam PF03308 ArgK protein 22 293 6.0E-114 T 28-03-2018 CU254_RS15790 02dfd775cb6887bbd117a1a9dac4d57a 676 Gene3D G3DSA:2.60.120.260 310 546 6.1E-69 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS15790 02dfd775cb6887bbd117a1a9dac4d57a 676 SMART SM00939 293 551 2.9E-90 T 28-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CU254_RS15790 02dfd775cb6887bbd117a1a9dac4d57a 676 SUPERFAMILY SSF49785 331 533 1.11E-58 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS15790 02dfd775cb6887bbd117a1a9dac4d57a 676 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 305 525 1.2E-56 T 28-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CU254_RS15790 02dfd775cb6887bbd117a1a9dac4d57a 676 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 25 276 1.0E-57 T 28-03-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 CU254_RS15790 02dfd775cb6887bbd117a1a9dac4d57a 676 SUPERFAMILY SSF53474 6 340 7.22E-72 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS15790 02dfd775cb6887bbd117a1a9dac4d57a 676 Gene3D G3DSA:3.40.50.1820 8 309 1.1E-43 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS15790 02dfd775cb6887bbd117a1a9dac4d57a 676 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 24 507 6.6E-69 T 28-03-2018 IPR005674 CocE/Serine esterase GO:0016787 CU254_RS39830 418c60851de8c2b1c0339d317cb3f53c 480 SUPERFAMILY SSF103473 268 475 8.76E-59 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS39830 418c60851de8c2b1c0339d317cb3f53c 480 SUPERFAMILY SSF103473 26 217 8.76E-59 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS39830 418c60851de8c2b1c0339d317cb3f53c 480 Gene3D G3DSA:1.20.1250.20 273 480 8.1E-20 T 28-03-2018 CU254_RS39830 418c60851de8c2b1c0339d317cb3f53c 480 PRINTS PR01036 Tetracycline resistance protein TetB signature 151 175 6.5E-5 T 28-03-2018 CU254_RS39830 418c60851de8c2b1c0339d317cb3f53c 480 PRINTS PR01036 Tetracycline resistance protein TetB signature 30 54 6.5E-5 T 28-03-2018 CU254_RS39830 418c60851de8c2b1c0339d317cb3f53c 480 PRINTS PR01036 Tetracycline resistance protein TetB signature 423 442 6.5E-5 T 28-03-2018 CU254_RS39830 418c60851de8c2b1c0339d317cb3f53c 480 PRINTS PR01036 Tetracycline resistance protein TetB signature 121 141 6.5E-5 T 28-03-2018 CU254_RS39830 418c60851de8c2b1c0339d317cb3f53c 480 Gene3D G3DSA:1.20.1250.20 22 215 1.4E-27 T 28-03-2018 CU254_RS39830 418c60851de8c2b1c0339d317cb3f53c 480 Pfam PF07690 Major Facilitator Superfamily 32 432 5.1E-43 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS04925 6da226b18685999d2b22c1aa8aadf570 553 Pfam PF01175 Urocanase Rossmann-like domain 137 344 6.8E-85 T 28-03-2018 IPR035085 Urocanase, Rossmann-like domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CU254_RS04925 6da226b18685999d2b22c1aa8aadf570 553 SUPERFAMILY SSF111326 5 550 1.14E-250 T 28-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CU254_RS04925 6da226b18685999d2b22c1aa8aadf570 553 TIGRFAM TIGR01228 hutU: urocanate hydratase 6 549 4.1E-279 T 28-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CU254_RS04925 6da226b18685999d2b22c1aa8aadf570 553 PIRSF PIRSF001423 1 553 2.4E-280 T 28-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CU254_RS04925 6da226b18685999d2b22c1aa8aadf570 553 Gene3D G3DSA:3.40.1770.10 192 549 2.1E-158 T 28-03-2018 CU254_RS04925 6da226b18685999d2b22c1aa8aadf570 553 Gene3D G3DSA:3.40.1770.10 6 149 1.6E-26 T 28-03-2018 CU254_RS04925 6da226b18685999d2b22c1aa8aadf570 553 Pfam PF17392 Urocanase C-terminal domain 347 541 7.9E-93 T 28-03-2018 IPR035401 Urocanase, C-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CU254_RS04925 6da226b18685999d2b22c1aa8aadf570 553 Hamap MF_00577 Urocanate hydratase [hutU]. 2 551 50.365 T 28-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CU254_RS04925 6da226b18685999d2b22c1aa8aadf570 553 Pfam PF17391 Urocanase N-terminal domain 8 134 9.2E-60 T 28-03-2018 IPR035400 Urocanase, N-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CU254_RS04925 6da226b18685999d2b22c1aa8aadf570 553 ProSitePatterns PS01233 Urocanase signature. 437 452 - T 28-03-2018 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CU254_RS01560 aee41ba853f20a4f2c830d0126f31432 373 SUPERFAMILY SSF53756 58 368 1.0E-51 T 28-03-2018 CU254_RS01560 aee41ba853f20a4f2c830d0126f31432 373 Gene3D G3DSA:3.40.50.2000 133 368 1.9E-34 T 28-03-2018 CU254_RS01560 aee41ba853f20a4f2c830d0126f31432 373 Pfam PF00534 Glycosyl transferases group 1 200 343 3.4E-26 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CU254_RS18290 69ef6212adede76fd28d8d3da7e79642 102 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 77 19.949 T 28-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 CU254_RS18290 69ef6212adede76fd28d8d3da7e79642 102 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 4 47 4.4E-18 T 28-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 CU254_RS18290 69ef6212adede76fd28d8d3da7e79642 102 Pfam PF02416 mttA/Hcf106 family 6 54 7.8E-19 T 28-03-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 CU254_RS42230 ae6a8dc0b1e12384a32ed659b5b970f5 317 SMART SM00857 89 236 6.5E-24 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CU254_RS42230 ae6a8dc0b1e12384a32ed659b5b970f5 317 SUPERFAMILY SSF53041 89 235 1.57E-23 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CU254_RS42230 ae6a8dc0b1e12384a32ed659b5b970f5 317 Gene3D G3DSA:3.40.50.1390 86 207 3.8E-17 T 28-03-2018 CU254_RS42230 ae6a8dc0b1e12384a32ed659b5b970f5 317 Pfam PF00239 Resolvase, N terminal domain 90 236 6.7E-26 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CU254_RS42230 ae6a8dc0b1e12384a32ed659b5b970f5 317 Gene3D G3DSA:1.20.5.40 208 234 3.0E-9 T 28-03-2018 CU254_RS21040 3b4215690e4c4c37c2fe3f419417f588 239 Pfam PF02308 MgtC family 12 133 8.5E-35 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CU254_RS21040 3b4215690e4c4c37c2fe3f419417f588 239 PRINTS PR01837 MgtC/SapB protein signature 32 50 3.7E-44 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CU254_RS21040 3b4215690e4c4c37c2fe3f419417f588 239 PRINTS PR01837 MgtC/SapB protein signature 60 82 3.7E-44 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CU254_RS21040 3b4215690e4c4c37c2fe3f419417f588 239 PRINTS PR01837 MgtC/SapB protein signature 13 32 3.7E-44 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CU254_RS21040 3b4215690e4c4c37c2fe3f419417f588 239 PRINTS PR01837 MgtC/SapB protein signature 87 111 3.7E-44 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CU254_RS09190 964d3dd4b56d4253ab8c532d05c8809f 245 SMART SM00849 20 212 7.3E-7 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS09190 964d3dd4b56d4253ab8c532d05c8809f 245 Gene3D G3DSA:3.60.15.10 3 245 2.1E-48 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS09190 964d3dd4b56d4253ab8c532d05c8809f 245 SUPERFAMILY SSF56281 5 243 3.01E-48 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS09190 964d3dd4b56d4253ab8c532d05c8809f 245 Pfam PF12706 Beta-lactamase superfamily domain 33 212 2.0E-24 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS28045 cdf6ad9119d12d8707cd48cc983906ae 472 Pfam PF04075 F420H(2)-dependent quinone reductase 344 470 1.2E-46 T 28-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CU254_RS28045 cdf6ad9119d12d8707cd48cc983906ae 472 Pfam PF00561 alpha/beta hydrolase fold 36 300 3.3E-25 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS28045 cdf6ad9119d12d8707cd48cc983906ae 472 SUPERFAMILY SSF50475 366 472 5.23E-5 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS28045 cdf6ad9119d12d8707cd48cc983906ae 472 SUPERFAMILY SSF53474 5 311 6.06E-58 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS28045 cdf6ad9119d12d8707cd48cc983906ae 472 PRINTS PR00111 Alpha/beta hydrolase fold signature 125 138 1.3E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS28045 cdf6ad9119d12d8707cd48cc983906ae 472 PRINTS PR00111 Alpha/beta hydrolase fold signature 111 124 1.3E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS28045 cdf6ad9119d12d8707cd48cc983906ae 472 PRINTS PR00111 Alpha/beta hydrolase fold signature 60 75 1.3E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS28045 cdf6ad9119d12d8707cd48cc983906ae 472 Gene3D G3DSA:3.40.50.1820 2 320 6.3E-59 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS28045 cdf6ad9119d12d8707cd48cc983906ae 472 TIGRFAM TIGR01249 pro_imino_pep_1: prolyl aminopeptidase 9 317 4.9E-112 T 28-03-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 CU254_RS28045 cdf6ad9119d12d8707cd48cc983906ae 472 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 360 470 3.2E-32 T 28-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CU254_RS28045 cdf6ad9119d12d8707cd48cc983906ae 472 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 111 125 1.4E-13 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CU254_RS28045 cdf6ad9119d12d8707cd48cc983906ae 472 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 37 45 1.4E-13 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CU254_RS28045 cdf6ad9119d12d8707cd48cc983906ae 472 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 63 74 1.4E-13 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CU254_RS28045 cdf6ad9119d12d8707cd48cc983906ae 472 Gene3D G3DSA:2.30.110.10 335 472 2.6E-39 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS24695 4b78db10e578ae5098fb5b77d4399409 272 SUPERFAMILY SSF46946 122 196 5.15E-16 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CU254_RS24695 4b78db10e578ae5098fb5b77d4399409 272 SMART SM00898 2 115 2.1E-14 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CU254_RS24695 4b78db10e578ae5098fb5b77d4399409 272 SUPERFAMILY SSF57716 219 261 5.13E-6 T 28-03-2018 CU254_RS24695 4b78db10e578ae5098fb5b77d4399409 272 SMART SM01232 123 213 1.4E-20 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CU254_RS24695 4b78db10e578ae5098fb5b77d4399409 272 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 2 103 8.1E-10 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CU254_RS24695 4b78db10e578ae5098fb5b77d4399409 272 Gene3D G3DSA:3.20.190.10 1 117 4.4E-25 T 28-03-2018 CU254_RS24695 4b78db10e578ae5098fb5b77d4399409 272 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 123 198 1.4E-9 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CU254_RS24695 4b78db10e578ae5098fb5b77d4399409 272 Gene3D G3DSA:1.10.8.50 118 261 5.7E-40 T 28-03-2018 CU254_RS24695 4b78db10e578ae5098fb5b77d4399409 272 SUPERFAMILY SSF81624 2 124 1.57E-23 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CU254_RS21460 bb38782422ca03df82fb22f0574ce9d2 406 SUPERFAMILY SSF82866 135 338 6.02E-30 T 28-03-2018 CU254_RS21460 bb38782422ca03df82fb22f0574ce9d2 406 Gene3D G3DSA:1.20.1640.10 117 351 1.6E-24 T 28-03-2018 CU254_RS21460 bb38782422ca03df82fb22f0574ce9d2 406 PRINTS PR01755 Bacterial translocase SecF protein signature 190 204 1.4E-20 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CU254_RS21460 bb38782422ca03df82fb22f0574ce9d2 406 PRINTS PR01755 Bacterial translocase SecF protein signature 238 256 1.4E-20 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CU254_RS21460 bb38782422ca03df82fb22f0574ce9d2 406 PRINTS PR01755 Bacterial translocase SecF protein signature 66 81 1.4E-20 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CU254_RS21460 bb38782422ca03df82fb22f0574ce9d2 406 PRINTS PR01755 Bacterial translocase SecF protein signature 273 288 1.4E-20 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CU254_RS21460 bb38782422ca03df82fb22f0574ce9d2 406 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 39 341 22.609 T 28-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 CU254_RS21460 bb38782422ca03df82fb22f0574ce9d2 406 Pfam PF02355 Protein export membrane protein 153 339 1.9E-54 T 28-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial CU254_RS21460 bb38782422ca03df82fb22f0574ce9d2 406 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 67 330 2.1E-64 T 28-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 CU254_RS21460 bb38782422ca03df82fb22f0574ce9d2 406 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 89 327 9.0E-47 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CU254_RS21460 bb38782422ca03df82fb22f0574ce9d2 406 Pfam PF07549 SecD/SecF GG Motif 62 83 7.3E-5 T 28-03-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site CU254_RS14480 4c2ccd2612689809513e1ea63459b54c 246 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 242 2.1E-41 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CU254_RS14480 4c2ccd2612689809513e1ea63459b54c 246 SUPERFAMILY SSF52096 3 242 3.64E-61 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS14480 4c2ccd2612689809513e1ea63459b54c 246 Gene3D G3DSA:3.90.226.10 1 244 5.8E-60 T 28-03-2018 CU254_RS11355 9b069409dbbb809852c650cd2ca45505 498 SUPERFAMILY SSF53474 181 235 2.48E-27 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS11355 9b069409dbbb809852c650cd2ca45505 498 SUPERFAMILY SSF53474 320 462 2.48E-27 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS11355 9b069409dbbb809852c650cd2ca45505 498 SUPERFAMILY SSF53474 95 144 2.48E-27 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS11355 9b069409dbbb809852c650cd2ca45505 498 Gene3D G3DSA:3.40.50.1820 67 483 2.1E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS11355 9b069409dbbb809852c650cd2ca45505 498 Pfam PF00561 alpha/beta hydrolase fold 94 238 3.6E-18 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS11355 9b069409dbbb809852c650cd2ca45505 498 Pfam PF08386 TAP-like protein 388 489 4.3E-21 T 28-03-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal CU254_RS40035 491676787f159c71eba1e230e6fe8f3a 222 Pfam PF06197 Protein of unknown function (DUF998) 26 212 5.7E-21 T 28-03-2018 IPR009339 Protein of unknown function DUF998 CU254_RS05100 e22ec49e57d91179e60125bd548999e6 358 Gene3D G3DSA:3.40.50.2300 173 356 2.0E-42 T 28-03-2018 CU254_RS05100 e22ec49e57d91179e60125bd548999e6 358 SUPERFAMILY SSF53822 68 352 2.02E-70 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CU254_RS05100 e22ec49e57d91179e60125bd548999e6 358 Gene3D G3DSA:3.40.50.2300 10 172 7.9E-17 T 28-03-2018 CU254_RS05100 e22ec49e57d91179e60125bd548999e6 358 Pfam PF13407 Periplasmic binding protein domain 80 332 8.4E-52 T 28-03-2018 IPR025997 Periplasmic binding protein CU254_RS03530 0a49ac2174bc01823ecbae3a91b7e316 324 SUPERFAMILY SSF51556 32 323 2.0E-67 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS03530 0a49ac2174bc01823ecbae3a91b7e316 324 Gene3D G3DSA:3.20.20.140 5 323 7.5E-56 T 28-03-2018 CU254_RS03530 0a49ac2174bc01823ecbae3a91b7e316 324 Pfam PF04909 Amidohydrolase 77 323 3.5E-34 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CU254_RS05485 2d6f54e92ca23cc4971157d83f5dc4ce 190 Gene3D G3DSA:3.40.30.10 42 190 2.3E-24 T 28-03-2018 CU254_RS05485 2d6f54e92ca23cc4971157d83f5dc4ce 190 ProSitePatterns PS00194 Thioredoxin family active site. 78 96 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CU254_RS05485 2d6f54e92ca23cc4971157d83f5dc4ce 190 Pfam PF00578 AhpC/TSA family 57 169 1.1E-16 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CU254_RS05485 2d6f54e92ca23cc4971157d83f5dc4ce 190 SUPERFAMILY SSF52833 45 189 1.77E-28 T 28-03-2018 IPR012336 Thioredoxin-like fold CU254_RS25765 a2d0fa4281d85d356285ee8cb3839542 183 SUPERFAMILY SSF54292 16 104 7.6E-25 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CU254_RS25765 a2d0fa4281d85d356285ee8cb3839542 183 Gene3D G3DSA:1.10.150.120 91 183 1.7E-33 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CU254_RS25765 a2d0fa4281d85d356285ee8cb3839542 183 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 55 63 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CU254_RS25765 a2d0fa4281d85d356285ee8cb3839542 183 Pfam PF01799 [2Fe-2S] binding domain 89 176 1.1E-28 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CU254_RS25765 a2d0fa4281d85d356285ee8cb3839542 183 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 22 78 1.2E-8 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CU254_RS25765 a2d0fa4281d85d356285ee8cb3839542 183 Gene3D G3DSA:3.10.20.30 15 90 2.6E-23 T 28-03-2018 IPR012675 Beta-grasp domain CU254_RS25765 a2d0fa4281d85d356285ee8cb3839542 183 SUPERFAMILY SSF47741 100 181 2.22E-26 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CU254_RS09555 ed3628891e0c53a418fb0892bf0999c1 181 Gene3D G3DSA:1.10.10.10 117 167 1.3E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS09555 ed3628891e0c53a418fb0892bf0999c1 181 Gene3D G3DSA:1.10.10.10 6 66 1.4E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS09555 ed3628891e0c53a418fb0892bf0999c1 181 Hamap MF_01114 Regulatory protein RecX [recX]. 2 168 14.721 T 28-03-2018 IPR003783 Regulatory protein RecX GO:0006282 CU254_RS09555 ed3628891e0c53a418fb0892bf0999c1 181 Pfam PF02631 RecX family 43 163 1.0E-27 T 28-03-2018 IPR003783 Regulatory protein RecX GO:0006282 CU254_RS09555 ed3628891e0c53a418fb0892bf0999c1 181 Gene3D G3DSA:1.10.10.10 68 112 4.5E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS29080 fee7ff24ad54ccb69846d72852a9e61a 335 SUPERFAMILY SSF52540 9 257 1.78E-66 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS29080 fee7ff24ad54ccb69846d72852a9e61a 335 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 236 322 8.8E-22 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CU254_RS29080 fee7ff24ad54ccb69846d72852a9e61a 335 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 238 303 7.9E-18 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CU254_RS29080 fee7ff24ad54ccb69846d72852a9e61a 335 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS29080 fee7ff24ad54ccb69846d72852a9e61a 335 Pfam PF00005 ABC transporter 29 186 4.1E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS29080 fee7ff24ad54ccb69846d72852a9e61a 335 Gene3D G3DSA:3.40.50.300 6 335 1.3E-75 T 28-03-2018 CU254_RS29080 fee7ff24ad54ccb69846d72852a9e61a 335 SMART SM00382 37 236 1.4E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS01695 7aab22da6cd88abbf2a3836d66298ca5 147 PIRSF PIRSF018072 1 147 6.4E-54 T 28-03-2018 IPR016709 Uncharacterised protein family UPF0336 CU254_RS01695 7aab22da6cd88abbf2a3836d66298ca5 147 Hamap MF_00799 UPF0336 protein . 1 146 30.559 T 28-03-2018 IPR016709 Uncharacterised protein family UPF0336 CU254_RS01695 7aab22da6cd88abbf2a3836d66298ca5 147 SUPERFAMILY SSF54637 6 145 1.09E-37 T 28-03-2018 IPR029069 HotDog domain CU254_RS01695 7aab22da6cd88abbf2a3836d66298ca5 147 Gene3D G3DSA:3.10.129.10 3 147 7.0E-42 T 28-03-2018 CU254_RS01695 7aab22da6cd88abbf2a3836d66298ca5 147 Pfam PF13452 N-terminal half of MaoC dehydratase 5 135 2.6E-34 T 28-03-2018 CU254_RS17645 2a393ed55dfd344504cdf70a28cc350f 485 Gene3D G3DSA:3.40.309.10 269 467 5.1E-71 T 28-03-2018 CU254_RS17645 2a393ed55dfd344504cdf70a28cc350f 485 SUPERFAMILY SSF53720 4 484 1.11E-158 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CU254_RS17645 2a393ed55dfd344504cdf70a28cc350f 485 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 252 259 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CU254_RS17645 2a393ed55dfd344504cdf70a28cc350f 485 Pfam PF00171 Aldehyde dehydrogenase family 18 481 5.1E-159 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CU254_RS17645 2a393ed55dfd344504cdf70a28cc350f 485 Gene3D G3DSA:3.40.605.10 1 268 2.5E-90 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CU254_RS17645 2a393ed55dfd344504cdf70a28cc350f 485 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 280 291 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CU254_RS17645 2a393ed55dfd344504cdf70a28cc350f 485 TIGRFAM TIGR03216 OH_muco_semi_DH: 2-hydroxymuconic semialdehyde dehydrogenase 6 485 4.4E-241 T 28-03-2018 IPR017628 2-hydroxymuconic semialdehyde dehydrogenase GO:0016620|GO:0055114 CU254_RS22470 1819e2c45d1d9aa86afd4e19f045ddca 533 Gene3D G3DSA:3.40.50.1820 30 478 6.2E-35 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS22470 1819e2c45d1d9aa86afd4e19f045ddca 533 SUPERFAMILY SSF53474 314 475 1.69E-20 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS22470 1819e2c45d1d9aa86afd4e19f045ddca 533 SUPERFAMILY SSF53474 88 139 1.69E-20 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS22470 1819e2c45d1d9aa86afd4e19f045ddca 533 SUPERFAMILY SSF53474 182 236 1.69E-20 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS22470 1819e2c45d1d9aa86afd4e19f045ddca 533 Pfam PF08386 TAP-like protein 389 483 2.3E-17 T 28-03-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal CU254_RS22470 1819e2c45d1d9aa86afd4e19f045ddca 533 Pfam PF00561 alpha/beta hydrolase fold 89 272 3.7E-26 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS20510 7f2d174efb00e334e136be9f3f8bf4f2 320 Gene3D G3DSA:2.120.10.30 19 134 1.5E-8 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CU254_RS20510 7f2d174efb00e334e136be9f3f8bf4f2 320 Gene3D G3DSA:2.130.10.10 135 303 5.7E-23 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CU254_RS20510 7f2d174efb00e334e136be9f3f8bf4f2 320 SUPERFAMILY SSF51004 41 301 6.67E-38 T 28-03-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain CU254_RS13420 ab6744336e595478e0c6e26cbbce4072 302 SUPERFAMILY SSF53756 2 296 3.14E-55 T 28-03-2018 CU254_RS13420 ab6744336e595478e0c6e26cbbce4072 302 Gene3D G3DSA:3.40.50.2000 1 122 1.5E-6 T 28-03-2018 CU254_RS13420 ab6744336e595478e0c6e26cbbce4072 302 Pfam PF06722 Protein of unknown function (DUF1205) 107 189 2.0E-23 T 28-03-2018 IPR010610 Domain of unknown function DUF1205 CU254_RS13420 ab6744336e595478e0c6e26cbbce4072 302 Gene3D G3DSA:3.40.50.2000 123 285 1.1E-37 T 28-03-2018 CU254_RS16630 204bbe2be5cc8595bafa2ad79ce597a1 197 Gene3D G3DSA:3.20.20.400 5 186 3.7E-43 T 28-03-2018 CU254_RS16630 204bbe2be5cc8595bafa2ad79ce597a1 197 SUPERFAMILY SSF110391 13 186 1.96E-37 T 28-03-2018 IPR006699 Glycerol-3-phosphate responsive antiterminator GO:0006355|GO:0009607 CU254_RS16630 204bbe2be5cc8595bafa2ad79ce597a1 197 PIRSF PIRSF016897 3 191 3.9E-40 T 28-03-2018 IPR006699 Glycerol-3-phosphate responsive antiterminator GO:0006355|GO:0009607 CU254_RS16630 204bbe2be5cc8595bafa2ad79ce597a1 197 Pfam PF04309 Glycerol-3-phosphate responsive antiterminator 15 185 5.2E-41 T 28-03-2018 IPR006699 Glycerol-3-phosphate responsive antiterminator GO:0006355|GO:0009607 CU254_RS13805 57f721b0a0a3f510660abb7d92423db6 211 SUPERFAMILY SSF46689 5 76 1.59E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS13805 57f721b0a0a3f510660abb7d92423db6 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 57 1.6E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS13805 57f721b0a0a3f510660abb7d92423db6 211 SUPERFAMILY SSF48498 89 206 4.45E-22 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS13805 57f721b0a0a3f510660abb7d92423db6 211 Gene3D G3DSA:1.10.357.10 1 211 1.7E-30 T 28-03-2018 CU254_RS13805 57f721b0a0a3f510660abb7d92423db6 211 ProSitePatterns PS01081 TetR-type HTH domain signature. 26 57 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CU254_RS13805 57f721b0a0a3f510660abb7d92423db6 211 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 92 203 1.5E-21 T 28-03-2018 CU254_RS24815 d77e5e90f28b72b14e035b51b3eba071 132 Pfam PF13840 ACT domain 61 122 7.6E-16 T 28-03-2018 IPR027795 GATS-like ACT domain CU254_RS24815 d77e5e90f28b72b14e035b51b3eba071 132 Gene3D G3DSA:3.30.2130.10 1 130 1.1E-26 T 28-03-2018 CU254_RS24815 d77e5e90f28b72b14e035b51b3eba071 132 PIRSF PIRSF008459 2 131 7.8E-29 T 28-03-2018 IPR016540 Uncharacterised conserved protein UCP008459 CU254_RS24815 d77e5e90f28b72b14e035b51b3eba071 132 SUPERFAMILY SSF55021 64 128 2.06E-15 T 28-03-2018 CU254_RS24815 d77e5e90f28b72b14e035b51b3eba071 132 SUPERFAMILY SSF55021 1 59 1.33E-10 T 28-03-2018 CU254_RS04505 65ab901d754a914a3b98a95dbe43d049 249 Pfam PF00117 Glutamine amidotransferase class-I 24 183 3.9E-13 T 28-03-2018 IPR017926 Glutamine amidotransferase CU254_RS04505 65ab901d754a914a3b98a95dbe43d049 249 Gene3D G3DSA:3.40.50.880 1 233 1.7E-36 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS04505 65ab901d754a914a3b98a95dbe43d049 249 SUPERFAMILY SSF52317 18 195 8.03E-37 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS04610 5ba769f07bdf19b1d131f1b8d8dcce44 364 SUPERFAMILY SSF69279 13 181 3.23E-6 T 28-03-2018 CU254_RS09975 1fd62a361344593452f21d94866abf3e 307 Pfam PF02219 Methylenetetrahydrofolate reductase 168 253 1.3E-4 T 28-03-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CU254_RS09975 1fd62a361344593452f21d94866abf3e 307 Gene3D G3DSA:3.20.20.220 4 279 6.3E-31 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like CU254_RS09975 1fd62a361344593452f21d94866abf3e 307 SUPERFAMILY SSF51730 11 274 8.83E-24 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like CU254_RS04205 3387071bfd86e40e08f1f0cc95ce7afa 326 Gene3D G3DSA:3.30.420.40 128 283 3.6E-31 T 28-03-2018 CU254_RS04205 3387071bfd86e40e08f1f0cc95ce7afa 326 SUPERFAMILY SSF53067 119 310 5.35E-33 T 28-03-2018 CU254_RS04205 3387071bfd86e40e08f1f0cc95ce7afa 326 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 8 305 2.2E-22 T 28-03-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 CU254_RS04205 3387071bfd86e40e08f1f0cc95ce7afa 326 Gene3D G3DSA:3.30.420.40 1 127 6.8E-15 T 28-03-2018 CU254_RS04205 3387071bfd86e40e08f1f0cc95ce7afa 326 SUPERFAMILY SSF53067 3 114 7.12E-12 T 28-03-2018 CU254_RS06815 66d02b2c21136179ca79366e26bf1ba1 501 Gene3D G3DSA:1.10.10.410 439 499 1.8E-15 T 28-03-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal CU254_RS06815 66d02b2c21136179ca79366e26bf1ba1 501 SUPERFAMILY SSF55931 19 321 1.44E-112 T 28-03-2018 CU254_RS06815 66d02b2c21136179ca79366e26bf1ba1 501 Pfam PF02934 GatB/GatE catalytic domain 20 314 2.8E-105 T 28-03-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 CU254_RS06815 66d02b2c21136179ca79366e26bf1ba1 501 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 16 500 35.794 T 28-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 CU254_RS06815 66d02b2c21136179ca79366e26bf1ba1 501 SMART SM00845 352 499 1.1E-55 T 28-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 CU254_RS06815 66d02b2c21136179ca79366e26bf1ba1 501 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 16 498 6.6E-144 T 28-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 CU254_RS06815 66d02b2c21136179ca79366e26bf1ba1 501 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 165 179 - T 28-03-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 CU254_RS06815 66d02b2c21136179ca79366e26bf1ba1 501 SUPERFAMILY SSF89095 352 498 6.67E-27 T 28-03-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 CU254_RS06815 66d02b2c21136179ca79366e26bf1ba1 501 Pfam PF02637 GatB domain 352 498 1.4E-39 T 28-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 CU254_RS32345 4aaedc9f0a2786238ae1b815310f98c1 208 Gene3D G3DSA:1.10.1740.10 8 89 2.8E-21 T 28-03-2018 CU254_RS32345 4aaedc9f0a2786238ae1b815310f98c1 208 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 29 187 4.9E-27 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS32345 4aaedc9f0a2786238ae1b815310f98c1 208 TIGRFAM TIGR02947 SigH_actino: RNA polymerase sigma-70 factor, TIGR02947 family 13 199 3.0E-107 T 28-03-2018 IPR014293 RNA polymerase sigma-70, actinobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS32345 4aaedc9f0a2786238ae1b815310f98c1 208 SUPERFAMILY SSF88659 132 188 1.07E-16 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS32345 4aaedc9f0a2786238ae1b815310f98c1 208 Gene3D G3DSA:1.10.10.10 90 191 6.4E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS32345 4aaedc9f0a2786238ae1b815310f98c1 208 Pfam PF04542 Sigma-70 region 2 29 92 1.2E-17 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS32345 4aaedc9f0a2786238ae1b815310f98c1 208 Pfam PF08281 Sigma-70, region 4 134 184 5.8E-15 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS32345 4aaedc9f0a2786238ae1b815310f98c1 208 SUPERFAMILY SSF88946 16 106 1.57E-23 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS07890 1bb6f3f766d68098fcbf35f7eca4c34c 158 SUPERFAMILY SSF51735 9 135 1.14E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS07890 1bb6f3f766d68098fcbf35f7eca4c34c 158 SMART SM00881 13 107 1.6E-17 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CU254_RS07890 1bb6f3f766d68098fcbf35f7eca4c34c 158 Gene3D G3DSA:3.40.50.720 14 137 6.8E-32 T 28-03-2018 CU254_RS07890 1bb6f3f766d68098fcbf35f7eca4c34c 158 Pfam PF13380 CoA binding domain 18 133 6.2E-37 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CU254_RS37790 213aab2a2c85033d2c46c25a31af87bd 475 Gene3D G3DSA:1.10.275.10 9 102 1.0E-14 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal CU254_RS37790 213aab2a2c85033d2c46c25a31af87bd 475 Gene3D G3DSA:1.10.40.30 382 452 2.4E-15 T 28-03-2018 CU254_RS37790 213aab2a2c85033d2c46c25a31af87bd 475 SUPERFAMILY SSF48557 10 454 1.38E-82 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 CU254_RS37790 213aab2a2c85033d2c46c25a31af87bd 475 Gene3D G3DSA:1.20.200.10 103 381 7.6E-56 T 28-03-2018 CU254_RS37790 213aab2a2c85033d2c46c25a31af87bd 475 SMART SM00998 368 453 8.7E-18 T 28-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CU254_RS37790 213aab2a2c85033d2c46c25a31af87bd 475 ProSitePatterns PS00163 Fumarate lyases signature. 279 288 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CU254_RS37790 213aab2a2c85033d2c46c25a31af87bd 475 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 11 452 1.1E-128 T 28-03-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CU254_RS37790 213aab2a2c85033d2c46c25a31af87bd 475 Pfam PF10397 Adenylosuccinate lyase C-terminus 369 452 5.4E-12 T 28-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CU254_RS37790 213aab2a2c85033d2c46c25a31af87bd 475 PRINTS PR00149 Fumarate lyase superfamily signature 143 161 2.7E-10 T 28-03-2018 IPR000362 Fumarate lyase family CU254_RS37790 213aab2a2c85033d2c46c25a31af87bd 475 PRINTS PR00149 Fumarate lyase superfamily signature 236 263 2.7E-10 T 28-03-2018 IPR000362 Fumarate lyase family CU254_RS37790 213aab2a2c85033d2c46c25a31af87bd 475 PRINTS PR00149 Fumarate lyase superfamily signature 279 295 2.7E-10 T 28-03-2018 IPR000362 Fumarate lyase family CU254_RS37790 213aab2a2c85033d2c46c25a31af87bd 475 PRINTS PR00149 Fumarate lyase superfamily signature 98 116 2.7E-10 T 28-03-2018 IPR000362 Fumarate lyase family CU254_RS37790 213aab2a2c85033d2c46c25a31af87bd 475 Pfam PF00206 Lyase 39 303 4.1E-22 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal CU254_RS28080 52f68a1aa87d48ea7071c945a8a02abc 236 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 82 154 2.3E-8 T 28-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 CU254_RS28080 52f68a1aa87d48ea7071c945a8a02abc 236 Gene3D G3DSA:1.10.260.40 48 100 3.7E-6 T 28-03-2018 CU254_RS28080 52f68a1aa87d48ea7071c945a8a02abc 236 Gene3D G3DSA:1.10.357.10 101 235 6.0E-12 T 28-03-2018 CU254_RS28080 52f68a1aa87d48ea7071c945a8a02abc 236 SUPERFAMILY SSF46689 21 80 1.33E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS28080 52f68a1aa87d48ea7071c945a8a02abc 236 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 69 4.8E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS28080 52f68a1aa87d48ea7071c945a8a02abc 236 Gene3D G3DSA:1.10.10.60 1 47 2.2E-9 T 28-03-2018 CU254_RS28080 52f68a1aa87d48ea7071c945a8a02abc 236 SUPERFAMILY SSF48498 89 232 4.34E-15 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS17150 641b990feee445fd520aee5fa9116435 411 Pfam PF13416 Bacterial extracellular solute-binding protein 63 354 9.5E-43 T 28-03-2018 CU254_RS17150 641b990feee445fd520aee5fa9116435 411 SUPERFAMILY SSF53850 46 408 9.32E-75 T 28-03-2018 CU254_RS17150 641b990feee445fd520aee5fa9116435 411 Gene3D G3DSA:3.40.190.10 148 409 4.5E-49 T 28-03-2018 CU254_RS25260 92855473b159ea043d4bf5ba2003bf47 632 SUPERFAMILY SSF52743 66 388 3.14E-38 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS25260 92855473b159ea043d4bf5ba2003bf47 632 Gene3D G3DSA:3.40.50.200 61 389 1.7E-29 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS25260 92855473b159ea043d4bf5ba2003bf47 632 Gene3D G3DSA:2.60.120.260 481 632 9.7E-20 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS25260 92855473b159ea043d4bf5ba2003bf47 632 Gene3D G3DSA:2.60.40.10 390 476 3.3E-13 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS25260 92855473b159ea043d4bf5ba2003bf47 632 SUPERFAMILY SSF49313 396 478 2.82E-10 T 28-03-2018 IPR015919 Cadherin-like GO:0005509|GO:0016020 CU254_RS41445 74f6ea023a80986397a33a4ce3c2716b 364 Gene3D G3DSA:3.20.20.210 53 354 4.9E-18 T 28-03-2018 CU254_RS41445 74f6ea023a80986397a33a4ce3c2716b 364 SUPERFAMILY SSF51726 14 353 1.6E-8 T 28-03-2018 CU254_RS24690 d247cb0dc19b9126f55cc6ccfb516510 283 Gene3D G3DSA:3.40.50.300 1 274 1.6E-48 T 28-03-2018 CU254_RS24690 d247cb0dc19b9126f55cc6ccfb516510 283 Pfam PF13614 AAA domain 3 181 4.7E-33 T 28-03-2018 IPR025669 AAA domain CU254_RS24690 d247cb0dc19b9126f55cc6ccfb516510 283 SUPERFAMILY SSF52540 2 256 4.98E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS13715 f7dedf7b79d479286f2bb700b3a7ef04 511 Gene3D G3DSA:3.60.21.10 142 511 5.4E-43 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CU254_RS13715 f7dedf7b79d479286f2bb700b3a7ef04 511 Pfam PF16656 Purple acid Phosphatase, N-terminal domain 45 137 1.9E-15 T 28-03-2018 IPR015914 Purple acid phosphatase, N-terminal GO:0003993|GO:0046872 CU254_RS13715 f7dedf7b79d479286f2bb700b3a7ef04 511 SUPERFAMILY SSF56300 144 493 1.9E-40 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CU254_RS13715 f7dedf7b79d479286f2bb700b3a7ef04 511 Pfam PF00149 Calcineurin-like phosphoesterase 187 367 1.4E-13 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CU254_RS13715 f7dedf7b79d479286f2bb700b3a7ef04 511 Gene3D G3DSA:2.60.40.380 42 141 1.9E-15 T 28-03-2018 CU254_RS13715 f7dedf7b79d479286f2bb700b3a7ef04 511 SUPERFAMILY SSF49363 35 139 1.7E-23 T 28-03-2018 IPR008963 Purple acid phosphatase-like, N-terminal GO:0003993|GO:0046872 CU254_RS13390 2d4f2009b6b13cdda365bb589c75d06e 295 Gene3D G3DSA:1.10.10.10 1 86 1.2E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS13390 2d4f2009b6b13cdda365bb589c75d06e 295 Gene3D G3DSA:3.40.190.10 95 181 7.9E-42 T 28-03-2018 CU254_RS13390 2d4f2009b6b13cdda365bb589c75d06e 295 Gene3D G3DSA:3.40.190.10 182 264 9.2E-7 T 28-03-2018 CU254_RS13390 2d4f2009b6b13cdda365bb589c75d06e 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 6.1E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS13390 2d4f2009b6b13cdda365bb589c75d06e 295 Pfam PF03466 LysR substrate binding domain 95 288 1.8E-13 T 28-03-2018 IPR005119 LysR, substrate-binding CU254_RS13390 2d4f2009b6b13cdda365bb589c75d06e 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 5.4E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS13390 2d4f2009b6b13cdda365bb589c75d06e 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 5.4E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS13390 2d4f2009b6b13cdda365bb589c75d06e 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 5.4E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS13390 2d4f2009b6b13cdda365bb589c75d06e 295 TIGRFAM TIGR03298 argP: transcriptional regulator, ArgP family 8 292 3.2E-109 T 28-03-2018 IPR017685 HTH-type transcriptional regulator ArgP CU254_RS13390 2d4f2009b6b13cdda365bb589c75d06e 295 SUPERFAMILY SSF46785 6 114 8.33E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS13390 2d4f2009b6b13cdda365bb589c75d06e 295 SUPERFAMILY SSF53850 91 290 2.9E-20 T 28-03-2018 CU254_RS20470 d7516966b4497ae94eed6f8bb4d591bf 586 Gene3D G3DSA:3.40.50.300 331 581 1.4E-49 T 28-03-2018 CU254_RS20470 d7516966b4497ae94eed6f8bb4d591bf 586 SUPERFAMILY SSF90123 18 332 6.02E-59 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CU254_RS20470 d7516966b4497ae94eed6f8bb4d591bf 586 Pfam PF00005 ABC transporter 359 508 6.7E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS20470 d7516966b4497ae94eed6f8bb4d591bf 586 SMART SM00382 368 554 3.7E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS20470 d7516966b4497ae94eed6f8bb4d591bf 586 Pfam PF00664 ABC transporter transmembrane region 32 299 2.1E-33 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CU254_RS20470 d7516966b4497ae94eed6f8bb4d591bf 586 Gene3D G3DSA:1.20.1560.10 9 330 2.6E-50 T 28-03-2018 CU254_RS20470 d7516966b4497ae94eed6f8bb4d591bf 586 SUPERFAMILY SSF52540 338 577 1.81E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS07160 5565cd6910ada88429c6b782a83083b5 528 SMART SM01120 34 196 7.5E-41 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CU254_RS07160 5565cd6910ada88429c6b782a83083b5 528 TIGRFAM TIGR03599 YloV: DAK2 domain fusion protein YloV 11 528 2.2E-121 T 28-03-2018 IPR019986 DAK2 domain-containing protein YloV CU254_RS07160 5565cd6910ada88429c6b782a83083b5 528 Pfam PF02734 DAK2 domain 34 195 1.7E-29 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CU254_RS07160 5565cd6910ada88429c6b782a83083b5 528 SUPERFAMILY SSF101473 4 197 4.45E-30 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CU254_RS07160 5565cd6910ada88429c6b782a83083b5 528 Pfam PF13684 Dihydroxyacetone kinase family 221 528 3.0E-61 T 28-03-2018 IPR033470 Uncharacterised protein, DhaK domain CU254_RS07160 5565cd6910ada88429c6b782a83083b5 528 SMART SM01121 220 528 9.5E-60 T 28-03-2018 IPR033470 Uncharacterised protein, DhaK domain CU254_RS23870 cf04362a0cfed29e7ba6c969d1e8b492 291 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 127 135 2.8E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23870 cf04362a0cfed29e7ba6c969d1e8b492 291 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 2.8E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23870 cf04362a0cfed29e7ba6c969d1e8b492 291 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 2.8E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23870 cf04362a0cfed29e7ba6c969d1e8b492 291 Pfam PF00106 short chain dehydrogenase 12 201 4.6E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23870 cf04362a0cfed29e7ba6c969d1e8b492 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 2.5E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23870 cf04362a0cfed29e7ba6c969d1e8b492 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 2.5E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23870 cf04362a0cfed29e7ba6c969d1e8b492 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 2.5E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23870 cf04362a0cfed29e7ba6c969d1e8b492 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 2.5E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23870 cf04362a0cfed29e7ba6c969d1e8b492 291 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 2.5E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23870 cf04362a0cfed29e7ba6c969d1e8b492 291 SUPERFAMILY SSF51735 9 236 2.64E-55 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS23870 cf04362a0cfed29e7ba6c969d1e8b492 291 Gene3D G3DSA:3.40.50.720 3 287 1.0E-63 T 28-03-2018 CU254_RS14435 b5fd35d20ad1a5081b7bb0a9ecc7e78f 276 Gene3D G3DSA:3.30.450.40 1 176 1.5E-14 T 28-03-2018 IPR029016 GAF domain-like CU254_RS14435 b5fd35d20ad1a5081b7bb0a9ecc7e78f 276 ProSitePatterns PS00622 LuxR-type HTH domain signature. 229 256 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS14435 b5fd35d20ad1a5081b7bb0a9ecc7e78f 276 Pfam PF01590 GAF domain 54 144 7.4E-5 T 28-03-2018 IPR003018 GAF domain GO:0005515 CU254_RS14435 b5fd35d20ad1a5081b7bb0a9ecc7e78f 276 SUPERFAMILY SSF55781 12 145 8.74E-12 T 28-03-2018 IPR029016 GAF domain-like CU254_RS14435 b5fd35d20ad1a5081b7bb0a9ecc7e78f 276 Pfam PF00196 Bacterial regulatory proteins, luxR family 214 268 3.1E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS14435 b5fd35d20ad1a5081b7bb0a9ecc7e78f 276 SUPERFAMILY SSF46894 209 275 1.29E-18 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS14435 b5fd35d20ad1a5081b7bb0a9ecc7e78f 276 SMART SM00421 212 269 1.2E-22 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS14435 b5fd35d20ad1a5081b7bb0a9ecc7e78f 276 Gene3D G3DSA:1.10.10.10 177 268 6.2E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS14435 b5fd35d20ad1a5081b7bb0a9ecc7e78f 276 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 215 229 5.3E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS14435 b5fd35d20ad1a5081b7bb0a9ecc7e78f 276 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 229 245 5.3E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS14435 b5fd35d20ad1a5081b7bb0a9ecc7e78f 276 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 245 257 5.3E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS11785 9dd0c4490a56496b9c0e362ef729d756 241 Pfam PF01061 ABC-2 type transporter 23 210 5.9E-16 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CU254_RS11785 9dd0c4490a56496b9c0e362ef729d756 241 PIRSF PIRSF006648 9 240 2.3E-22 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CU254_RS21000 05b696da7db776074889a985749c2439 285 Pfam PF04542 Sigma-70 region 2 10 70 1.3E-15 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS21000 05b696da7db776074889a985749c2439 285 SUPERFAMILY SSF54427 163 273 4.52E-11 T 28-03-2018 IPR032710 NTF2-like domain CU254_RS21000 05b696da7db776074889a985749c2439 285 SUPERFAMILY SSF88946 3 80 2.67E-14 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS21000 05b696da7db776074889a985749c2439 285 SUPERFAMILY SSF88659 90 151 3.27E-7 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS21000 05b696da7db776074889a985749c2439 285 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 4 151 2.9E-15 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS21000 05b696da7db776074889a985749c2439 285 Gene3D G3DSA:3.10.450.50 142 275 2.5E-17 T 28-03-2018 CU254_RS21000 05b696da7db776074889a985749c2439 285 Gene3D G3DSA:1.10.1740.10 1 73 2.2E-15 T 28-03-2018 CU254_RS21000 05b696da7db776074889a985749c2439 285 Gene3D G3DSA:1.10.10.10 78 141 7.1E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS08160 59ca6b68f83e76891263a288c6ed9ac1 320 SUPERFAMILY SSF51556 5 311 3.37E-60 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS08160 59ca6b68f83e76891263a288c6ed9ac1 320 Pfam PF04909 Amidohydrolase 6 311 1.3E-32 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CU254_RS08160 59ca6b68f83e76891263a288c6ed9ac1 320 Gene3D G3DSA:3.20.20.140 1 318 4.1E-45 T 28-03-2018 CU254_RS32985 9ef51ddda1b157b2458c296b643120a4 400 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 19 304 1.2E-81 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CU254_RS32985 9ef51ddda1b157b2458c296b643120a4 400 TIGRFAM TIGR01127 ilvA_1Cterm: threonine ammonia-lyase 23 399 4.0E-132 T 28-03-2018 IPR005789 Threonine dehydratase, catabolic GO:0004794|GO:0006567 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 CU254_RS32985 9ef51ddda1b157b2458c296b643120a4 400 Gene3D G3DSA:3.40.50.1100 138 309 3.5E-44 T 28-03-2018 CU254_RS32985 9ef51ddda1b157b2458c296b643120a4 400 SUPERFAMILY SSF53686 7 313 5.24E-92 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CU254_RS32985 9ef51ddda1b157b2458c296b643120a4 400 Gene3D G3DSA:3.40.50.1100 32 137 2.4E-28 T 28-03-2018 CU254_RS32985 9ef51ddda1b157b2458c296b643120a4 400 Gene3D G3DSA:3.30.70.260 326 399 6.8E-6 T 28-03-2018 CU254_RS32985 9ef51ddda1b157b2458c296b643120a4 400 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 44 57 - T 28-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 CU254_RS23495 4fbd0d428d5786545aa7e2ba45d960c5 339 Gene3D G3DSA:1.20.120.380 234 317 8.2E-29 T 28-03-2018 IPR027362 DNA topoisomerase I catalytic fragment, domain 2 CU254_RS23495 4fbd0d428d5786545aa7e2ba45d960c5 339 SUPERFAMILY SSF55869 22 83 7.19E-21 T 28-03-2018 IPR035447 DNA topoisomerase I, N-terminal CU254_RS23495 4fbd0d428d5786545aa7e2ba45d960c5 339 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 232 246 2.1E-7 T 28-03-2018 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 CU254_RS23495 4fbd0d428d5786545aa7e2ba45d960c5 339 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 145 159 2.1E-7 T 28-03-2018 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 CU254_RS23495 4fbd0d428d5786545aa7e2ba45d960c5 339 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 122 141 2.1E-7 T 28-03-2018 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 CU254_RS23495 4fbd0d428d5786545aa7e2ba45d960c5 339 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 283 294 2.1E-7 T 28-03-2018 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 CU254_RS23495 4fbd0d428d5786545aa7e2ba45d960c5 339 Gene3D G3DSA:3.30.66.10 15 80 6.7E-33 T 28-03-2018 IPR035447 DNA topoisomerase I, N-terminal CU254_RS23495 4fbd0d428d5786545aa7e2ba45d960c5 339 SUPERFAMILY SSF56349 78 307 1.13E-57 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CU254_RS23495 4fbd0d428d5786545aa7e2ba45d960c5 339 Pfam PF01028 Eukaryotic DNA topoisomerase I, catalytic core 83 286 4.5E-24 T 28-03-2018 IPR013500 DNA topoisomerase I, catalytic core, eukaryotic-type GO:0003677|GO:0003917|GO:0006265 CU254_RS23495 4fbd0d428d5786545aa7e2ba45d960c5 339 Gene3D G3DSA:3.90.15.10 81 228 4.3E-33 T 28-03-2018 IPR014711 DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type GO:0003677|GO:0003917|GO:0006265 CU254_RS26505 02735cd13479f8d42199fb208e61461a 548 Pfam PF07905 Purine catabolism regulatory protein-like family 7 129 4.8E-37 T 28-03-2018 IPR012914 Purine catabolism PurC-like domain CU254_RS26505 02735cd13479f8d42199fb208e61461a 548 Pfam PF13556 PucR C-terminal helix-turn-helix domain 470 528 3.4E-13 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CU254_RS13175 15b7cfb99527dba4023258b167b0577d 321 SUPERFAMILY SSF54919 62 204 1.57E-12 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CU254_RS13175 15b7cfb99527dba4023258b167b0577d 321 Gene3D G3DSA:3.30.70.141 61 217 4.4E-15 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CU254_RS13175 15b7cfb99527dba4023258b167b0577d 321 Pfam PF00334 Nucleoside diphosphate kinase 63 200 1.1E-8 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CU254_RS26020 a1d0f7772ae03201443c652c9bb3a604 182 Pfam PF13683 Integrase core domain 86 151 4.9E-14 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CU254_RS26020 a1d0f7772ae03201443c652c9bb3a604 182 Gene3D G3DSA:3.30.420.10 1 161 1.1E-22 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS26020 a1d0f7772ae03201443c652c9bb3a604 182 SUPERFAMILY SSF53098 4 151 1.14E-18 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS28605 bd046d4ff4245e65f98bccf7e6b651a2 63 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 5 51 2.6E-5 T 28-03-2018 IPR022536 ESX-1 secretion-associated protein EspC GO:0009306 CU254_RS28605 bd046d4ff4245e65f98bccf7e6b651a2 63 Gene3D G3DSA:1.10.287.1060 2 54 4.5E-5 T 28-03-2018 CU254_RS38880 6b48c7eb892f3e393fd8a841d02656e3 185 SUPERFAMILY SSF46785 2 172 9.98E-33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS38880 6b48c7eb892f3e393fd8a841d02656e3 185 Gene3D G3DSA:1.10.10.10 1 97 8.1E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS38880 6b48c7eb892f3e393fd8a841d02656e3 185 Pfam PF03551 Transcriptional regulator PadR-like family 6 84 1.7E-17 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CU254_RS25255 89ebc6d3385c40d94d75d831c191e3ab 336 Pfam PF00196 Bacterial regulatory proteins, luxR family 264 314 7.7E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS25255 89ebc6d3385c40d94d75d831c191e3ab 336 SMART SM00421 257 314 2.9E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS25255 89ebc6d3385c40d94d75d831c191e3ab 336 Gene3D G3DSA:1.10.10.10 92 324 6.8E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS25255 89ebc6d3385c40d94d75d831c191e3ab 336 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 11 65 6.2E-7 T 28-03-2018 IPR002831 Transcription regulator TrmB, N-terminal CU254_RS25255 89ebc6d3385c40d94d75d831c191e3ab 336 SUPERFAMILY SSF46894 261 321 1.56E-11 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS25255 89ebc6d3385c40d94d75d831c191e3ab 336 Gene3D G3DSA:1.10.10.10 5 91 1.8E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS28510 87e5df12ecc3d89d36afa517d8208c8d 253 SUPERFAMILY SSF53790 2 230 3.66E-60 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CU254_RS28510 87e5df12ecc3d89d36afa517d8208c8d 253 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 2 208 6.4E-42 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CU254_RS28510 87e5df12ecc3d89d36afa517d8208c8d 253 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 6 20 - T 28-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CU254_RS28510 87e5df12ecc3d89d36afa517d8208c8d 253 Gene3D G3DSA:3.30.950.10 121 234 3.7E-21 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CU254_RS28510 87e5df12ecc3d89d36afa517d8208c8d 253 Gene3D G3DSA:3.40.1010.10 1 120 4.4E-32 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CU254_RS28510 87e5df12ecc3d89d36afa517d8208c8d 253 TIGRFAM TIGR01465 cobM_cbiF: precorrin-4 C11-methyltransferase 3 243 5.9E-79 T 28-03-2018 IPR006362 Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase GO:0009236|GO:0046026 CU254_RS39560 69132529b0e10611e963c134727d8ce8 244 SMART SM00020 23 239 7.5E-6 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CU254_RS39560 69132529b0e10611e963c134727d8ce8 244 Gene3D G3DSA:2.40.10.10 24 63 1.7E-7 T 28-03-2018 CU254_RS39560 69132529b0e10611e963c134727d8ce8 244 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 116 130 2.9E-6 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CU254_RS39560 69132529b0e10611e963c134727d8ce8 244 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 194 206 2.9E-6 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CU254_RS39560 69132529b0e10611e963c134727d8ce8 244 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 59 74 2.9E-6 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CU254_RS39560 69132529b0e10611e963c134727d8ce8 244 Gene3D G3DSA:2.40.10.10 64 128 6.3E-11 T 28-03-2018 CU254_RS39560 69132529b0e10611e963c134727d8ce8 244 Pfam PF00089 Trypsin 26 239 3.3E-18 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CU254_RS39560 69132529b0e10611e963c134727d8ce8 244 Gene3D G3DSA:2.40.10.10 129 244 2.3E-9 T 28-03-2018 CU254_RS39560 69132529b0e10611e963c134727d8ce8 244 SUPERFAMILY SSF50494 12 243 6.33E-28 T 28-03-2018 IPR009003 Peptidase S1, PA clan CU254_RS28235 2e65441792879845396a3459fd1aab9d 185 Gene3D G3DSA:3.10.450.50 12 144 4.5E-23 T 28-03-2018 CU254_RS28235 2e65441792879845396a3459fd1aab9d 185 Pfam PF07366 SnoaL-like polyketide cyclase 20 142 3.9E-17 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CU254_RS28235 2e65441792879845396a3459fd1aab9d 185 SUPERFAMILY SSF54427 16 142 4.98E-27 T 28-03-2018 IPR032710 NTF2-like domain CU254_RS22260 782c30817d5071c5763c501bb82d1b9c 122 Pfam PF14087 Domain of unknown function (DUF4267) 14 118 1.4E-19 T 28-03-2018 IPR025363 Protein of unknown function DUF4267 CU254_RS07565 080a29b1ff982a7fb35121c6208f5fb9 259 ProSitePatterns PS01151 Fimbrial biogenesis outer membrane usher protein signature. 59 69 - T 28-03-2018 IPR018030 Fimbrial membrane usher, conserved site CU254_RS07565 080a29b1ff982a7fb35121c6208f5fb9 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 43 58 6.3E-9 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS07565 080a29b1ff982a7fb35121c6208f5fb9 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 101 114 6.3E-9 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS07565 080a29b1ff982a7fb35121c6208f5fb9 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 200 214 6.3E-9 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS07565 080a29b1ff982a7fb35121c6208f5fb9 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 87 100 6.3E-9 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS07565 080a29b1ff982a7fb35121c6208f5fb9 259 Gene3D G3DSA:3.40.50.1820 1 259 1.3E-50 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS07565 080a29b1ff982a7fb35121c6208f5fb9 259 SUPERFAMILY SSF53474 2 253 8.41E-65 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS07565 080a29b1ff982a7fb35121c6208f5fb9 259 TIGRFAM TIGR02427 protocat_pcaD: 3-oxoadipate enol-lactonase 6 252 1.0E-88 T 28-03-2018 IPR026968 3-oxoadipate enol-lactonase 1/2 GO:0042952|GO:0047570 KEGG: 00362+3.1.1.24|MetaCyc: PWY-6185 CU254_RS07565 080a29b1ff982a7fb35121c6208f5fb9 259 Pfam PF00561 alpha/beta hydrolase fold 17 242 1.5E-19 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS26630 2aeef7e5c61e5be336e357fffaa0c93a 191 Pfam PF12840 Helix-turn-helix domain 11 67 2.2E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS26630 2aeef7e5c61e5be336e357fffaa0c93a 191 Gene3D G3DSA:1.10.10.10 2 110 2.6E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS26630 2aeef7e5c61e5be336e357fffaa0c93a 191 SUPERFAMILY SSF46785 7 117 1.12E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS26630 2aeef7e5c61e5be336e357fffaa0c93a 191 SMART SM00418 10 92 6.8E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS26630 2aeef7e5c61e5be336e357fffaa0c93a 191 Gene3D G3DSA:1.10.10.10 111 179 0.5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS35740 967740252e3dc152deeeb60fa8944cb7 180 Gene3D G3DSA:3.40.50.300 1 168 7.4E-21 T 28-03-2018 CU254_RS35740 967740252e3dc152deeeb60fa8944cb7 180 PIRSF PIRSF007531 1 180 3.7E-51 T 28-03-2018 IPR012853 Chloramphenicol phosphotransferase-like GO:0005524|GO:0016740 CU254_RS35740 967740252e3dc152deeeb60fa8944cb7 180 Pfam PF07931 Chloramphenicol phosphotransferase-like protein 3 165 9.2E-47 T 28-03-2018 IPR012853 Chloramphenicol phosphotransferase-like GO:0005524|GO:0016740 CU254_RS35740 967740252e3dc152deeeb60fa8944cb7 180 SUPERFAMILY SSF52540 1 167 1.69E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS00990 346a838e1f2907165ac5ea5bc915d211 166 Pfam PF10698 Protein of unknown function (DUF2505) 7 162 9.5E-42 T 28-03-2018 IPR019639 Protein of unknown function DUF2505 CU254_RS00990 346a838e1f2907165ac5ea5bc915d211 166 Gene3D G3DSA:3.30.530.20 1 165 4.7E-4 T 28-03-2018 IPR023393 START-like domain CU254_RS11375 182c8f38640de8cecedb9ab17fc8fa62 265 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 59 75 5.6E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS11375 182c8f38640de8cecedb9ab17fc8fa62 265 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 59 5.6E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS11375 182c8f38640de8cecedb9ab17fc8fa62 265 SUPERFAMILY SSF46785 20 92 1.92E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS11375 182c8f38640de8cecedb9ab17fc8fa62 265 Gene3D G3DSA:1.10.10.10 15 87 1.1E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS11375 182c8f38640de8cecedb9ab17fc8fa62 265 Pfam PF07702 UTRA domain 106 243 1.5E-34 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CU254_RS11375 182c8f38640de8cecedb9ab17fc8fa62 265 SMART SM00345 26 85 6.7E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS11375 182c8f38640de8cecedb9ab17fc8fa62 265 SMART SM00866 105 243 1.0E-37 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CU254_RS11375 182c8f38640de8cecedb9ab17fc8fa62 265 SUPERFAMILY SSF64288 73 251 1.19E-47 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CU254_RS11375 182c8f38640de8cecedb9ab17fc8fa62 265 Pfam PF00392 Bacterial regulatory proteins, gntR family 29 84 1.3E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS11375 182c8f38640de8cecedb9ab17fc8fa62 265 Gene3D G3DSA:3.40.1410.10 89 255 4.0E-45 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CU254_RS17655 89894b3930c20943090a467226d93d53 143 Pfam PF01042 Endoribonuclease L-PSP 15 136 1.9E-27 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family CU254_RS17655 89894b3930c20943090a467226d93d53 143 SUPERFAMILY SSF55298 10 138 2.67E-36 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CU254_RS17655 89894b3930c20943090a467226d93d53 143 Gene3D G3DSA:3.30.1330.40 9 143 5.5E-35 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CU254_RS28285 90ef2085cb0a19211e2cb00be3ed17c2 331 SUPERFAMILY SSF47413 2 62 9.28E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS28285 90ef2085cb0a19211e2cb00be3ed17c2 331 Gene3D G3DSA:1.10.260.40 4 58 1.6E-21 T 28-03-2018 CU254_RS28285 90ef2085cb0a19211e2cb00be3ed17c2 331 Pfam PF00356 Bacterial regulatory proteins, lacI family 7 51 1.1E-14 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CU254_RS28285 90ef2085cb0a19211e2cb00be3ed17c2 331 SMART SM00354 3 74 5.8E-27 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CU254_RS28285 90ef2085cb0a19211e2cb00be3ed17c2 331 Gene3D G3DSA:3.40.50.2300 59 177 1.2E-31 T 28-03-2018 CU254_RS28285 90ef2085cb0a19211e2cb00be3ed17c2 331 Gene3D G3DSA:3.40.50.2300 178 308 2.2E-31 T 28-03-2018 CU254_RS28285 90ef2085cb0a19211e2cb00be3ed17c2 331 Pfam PF13377 Periplasmic binding protein-like domain 171 328 2.3E-27 T 28-03-2018 CU254_RS28285 90ef2085cb0a19211e2cb00be3ed17c2 331 SUPERFAMILY SSF53822 65 329 3.21E-53 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CU254_RS20520 0894d5fed2ba4f5d5bd4ba41aa12c3c7 148 Pfam PF03625 Domain of unknown function DUF302 50 113 1.0E-26 T 28-03-2018 IPR005180 Domain of unknown function DUF302 CU254_RS20520 0894d5fed2ba4f5d5bd4ba41aa12c3c7 148 SUPERFAMILY SSF103247 26 143 5.23E-34 T 28-03-2018 IPR005180 Domain of unknown function DUF302 CU254_RS20520 0894d5fed2ba4f5d5bd4ba41aa12c3c7 148 PIRSF PIRSF021774 16 145 1.0E-40 T 28-03-2018 IPR016796 Uncharacterised conserved protein UCP021774 CU254_RS20520 0894d5fed2ba4f5d5bd4ba41aa12c3c7 148 Gene3D G3DSA:3.30.310.70 20 144 8.3E-34 T 28-03-2018 IPR005180 Domain of unknown function DUF302 CU254_RS27105 258126e2ef78cd933ada1180812eee11 297 Pfam PF13560 Helix-turn-helix domain 23 85 4.9E-12 T 28-03-2018 CU254_RS27105 258126e2ef78cd933ada1180812eee11 297 Gene3D G3DSA:1.10.3100.10 17 168 3.9E-16 T 28-03-2018 IPR027910 YdiL-like domain CU254_RS27105 258126e2ef78cd933ada1180812eee11 297 SUPERFAMILY SSF47413 21 81 6.97E-13 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS27105 258126e2ef78cd933ada1180812eee11 297 SMART SM00530 27 82 3.6E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS32275 a6130ba7eb3cc6f0e1ff05097031b73e 362 SMART SM00382 28 214 2.8E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS32275 a6130ba7eb3cc6f0e1ff05097031b73e 362 Pfam PF00005 ABC transporter 20 164 2.4E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS32275 a6130ba7eb3cc6f0e1ff05097031b73e 362 SUPERFAMILY SSF52540 3 240 3.88E-75 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS32275 a6130ba7eb3cc6f0e1ff05097031b73e 362 Gene3D G3DSA:3.40.50.300 1 242 2.1E-74 T 28-03-2018 CU254_RS32275 a6130ba7eb3cc6f0e1ff05097031b73e 362 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS18355 a83662529621356449519a1f360d5e64 358 SUPERFAMILY SSF52266 46 333 4.66E-40 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CU254_RS18355 a83662529621356449519a1f360d5e64 358 Gene3D G3DSA:3.40.50.1110 43 339 1.5E-26 T 28-03-2018 CU254_RS18355 a83662529621356449519a1f360d5e64 358 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 52 324 2.7E-17 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CU254_RS15705 e2edbcb64e6195638c94212882b09b31 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 71 87 2.4E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS15705 e2edbcb64e6195638c94212882b09b31 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 107 123 2.4E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS15705 e2edbcb64e6195638c94212882b09b31 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 103 2.4E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS15705 e2edbcb64e6195638c94212882b09b31 170 Gene3D G3DSA:1.10.10.10 18 169 7.5E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS15705 e2edbcb64e6195638c94212882b09b31 170 Pfam PF12802 MarR family 54 111 6.1E-11 T 28-03-2018 CU254_RS15705 e2edbcb64e6195638c94212882b09b31 170 SMART SM00347 47 147 2.4E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS15705 e2edbcb64e6195638c94212882b09b31 170 SUPERFAMILY SSF46785 27 162 1.87E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS02080 49fa04e853546277661b109d5e8e7428 126 Gene3D G3DSA:1.10.8.50 1 67 4.2E-24 T 28-03-2018 CU254_RS02080 49fa04e853546277661b109d5e8e7428 126 PIRSF PIRSF002134 1 125 1.0E-41 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS02080 49fa04e853546277661b109d5e8e7428 126 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 115 1.9E-50 T 28-03-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS02080 49fa04e853546277661b109d5e8e7428 126 Gene3D G3DSA:4.10.910.10 87 122 1.5E-23 T 28-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS02080 49fa04e853546277661b109d5e8e7428 126 Gene3D G3DSA:4.10.910.10 68 86 9.1E-14 T 28-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS02080 49fa04e853546277661b109d5e8e7428 126 Pfam PF00416 Ribosomal protein S13/S18 3 109 3.4E-31 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS02080 49fa04e853546277661b109d5e8e7428 126 SUPERFAMILY SSF46946 2 122 7.91E-44 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CU254_RS02080 49fa04e853546277661b109d5e8e7428 126 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 120 26.576 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS41000 8b563bd115894c8b1cfc473232e002e2 250 SUPERFAMILY SSF52540 19 223 1.81E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS41000 8b563bd115894c8b1cfc473232e002e2 250 Gene3D G3DSA:3.40.50.300 18 237 2.9E-23 T 28-03-2018 CU254_RS41000 8b563bd115894c8b1cfc473232e002e2 250 Hamap MF_00165 Thymidylate kinase [tmk]. 21 242 12.839 T 28-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CU254_RS41000 8b563bd115894c8b1cfc473232e002e2 250 Pfam PF02223 Thymidylate kinase 25 205 9.5E-7 T 28-03-2018 CU254_RS11105 f6a9709ef79b812faf4ee46cd4950eae 276 TIGRFAM TIGR04222 near_uncomplex: TIGR04222 domain 15 231 3.8E-43 T 28-03-2018 IPR026467 Ser/Gly rich, Cys interspersed, C-terminal domain CU254_RS11105 f6a9709ef79b812faf4ee46cd4950eae 276 Gene3D G3DSA:1.10.10.10 113 209 0.17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS11105 f6a9709ef79b812faf4ee46cd4950eae 276 Gene3D G3DSA:1.10.10.10 35 112 0.051 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS10800 ad914553b69468112fc819269cade002 402 SUPERFAMILY SSF55874 284 384 8.2E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS10800 ad914553b69468112fc819269cade002 402 Pfam PF07730 Histidine kinase 202 266 9.7E-16 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CU254_RS10800 ad914553b69468112fc819269cade002 402 Gene3D G3DSA:3.30.565.10 266 402 2.7E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS16050 f441352c534bf7d96b74f9b713e4767a 471 Pfam PF00027 Cyclic nucleotide-binding domain 116 203 8.0E-12 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CU254_RS16050 f441352c534bf7d96b74f9b713e4767a 471 SMART SM00100 96 219 9.6E-8 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CU254_RS16050 f441352c534bf7d96b74f9b713e4767a 471 SUPERFAMILY SSF51206 91 210 3.67E-19 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like CU254_RS16050 f441352c534bf7d96b74f9b713e4767a 471 Gene3D G3DSA:2.60.120.10 92 217 8.2E-18 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS32385 c9f398f72307799a3a640ffe583054f3 251 Pfam PF02586 SOS response associated peptidase (SRAP) 1 227 2.4E-68 T 28-03-2018 IPR003738 SOS response associated peptidase (SRAP) CU254_RS32385 c9f398f72307799a3a640ffe583054f3 251 Gene3D G3DSA:3.90.1680.10 1 246 1.1E-76 T 28-03-2018 IPR003738 SOS response associated peptidase (SRAP) CU254_RS32385 c9f398f72307799a3a640ffe583054f3 251 SUPERFAMILY SSF143081 2 237 9.42E-66 T 28-03-2018 IPR003738 SOS response associated peptidase (SRAP) CU254_RS24780 c8fd9b9afc2202878be70e3033bc9f4d 271 SUPERFAMILY SSF69593 30 222 1.31E-26 T 28-03-2018 CU254_RS24780 c8fd9b9afc2202878be70e3033bc9f4d 271 SMART SM00563 51 171 8.9E-30 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CU254_RS24780 c8fd9b9afc2202878be70e3033bc9f4d 271 Pfam PF01553 Acyltransferase 37 167 3.7E-18 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CU254_RS24780 c8fd9b9afc2202878be70e3033bc9f4d 271 Gene3D G3DSA:3.40.1130.10 7 248 1.5E-33 T 28-03-2018 CU254_RS02945 e9dfcb60dbecd1ad8f2e89d1bce6946e 401 PRINTS PR00359 B-class P450 signature 156 171 3.9E-55 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS02945 e9dfcb60dbecd1ad8f2e89d1bce6946e 401 PRINTS PR00359 B-class P450 signature 92 103 3.9E-55 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS02945 e9dfcb60dbecd1ad8f2e89d1bce6946e 401 PRINTS PR00359 B-class P450 signature 274 285 3.9E-55 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS02945 e9dfcb60dbecd1ad8f2e89d1bce6946e 401 PRINTS PR00359 B-class P450 signature 139 155 3.9E-55 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS02945 e9dfcb60dbecd1ad8f2e89d1bce6946e 401 PRINTS PR00359 B-class P450 signature 350 361 3.9E-55 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS02945 e9dfcb60dbecd1ad8f2e89d1bce6946e 401 PRINTS PR00359 B-class P450 signature 292 319 3.9E-55 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS02945 e9dfcb60dbecd1ad8f2e89d1bce6946e 401 PRINTS PR00359 B-class P450 signature 320 335 3.9E-55 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS02945 e9dfcb60dbecd1ad8f2e89d1bce6946e 401 PRINTS PR00359 B-class P450 signature 193 215 3.9E-55 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS02945 e9dfcb60dbecd1ad8f2e89d1bce6946e 401 PRINTS PR00359 B-class P450 signature 341 350 3.9E-55 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS02945 e9dfcb60dbecd1ad8f2e89d1bce6946e 401 Pfam PF00067 Cytochrome P450 275 370 1.9E-21 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS02945 e9dfcb60dbecd1ad8f2e89d1bce6946e 401 Gene3D G3DSA:1.10.630.10 2 401 4.6E-72 T 28-03-2018 CU254_RS02945 e9dfcb60dbecd1ad8f2e89d1bce6946e 401 SUPERFAMILY SSF48264 12 401 6.68E-91 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS02945 e9dfcb60dbecd1ad8f2e89d1bce6946e 401 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 343 352 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CU254_RS02945 e9dfcb60dbecd1ad8f2e89d1bce6946e 401 PRINTS PR00385 P450 superfamily signature 341 350 1.4E-8 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS02945 e9dfcb60dbecd1ad8f2e89d1bce6946e 401 PRINTS PR00385 P450 superfamily signature 239 256 1.4E-8 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS02945 e9dfcb60dbecd1ad8f2e89d1bce6946e 401 PRINTS PR00385 P450 superfamily signature 350 361 1.4E-8 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS02945 e9dfcb60dbecd1ad8f2e89d1bce6946e 401 PRINTS PR00385 P450 superfamily signature 274 285 1.4E-8 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS18325 06495c757037899b87b114bb908fc45d 405 SUPERFAMILY SSF55729 6 303 1.91E-49 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS18325 06495c757037899b87b114bb908fc45d 405 Hamap MF_01812 UPF0256 protein . 3 405 31.318 T 28-03-2018 IPR022902 N-acetyltransferase Eis CU254_RS18325 06495c757037899b87b114bb908fc45d 405 Pfam PF13530 Sterol carrier protein domain 179 401 5.5E-53 T 28-03-2018 IPR025559 Enhanced intracellular survival protein domain CU254_RS18325 06495c757037899b87b114bb908fc45d 405 Gene3D G3DSA:3.40.630.30 1 135 9.8E-12 T 28-03-2018 CU254_RS18325 06495c757037899b87b114bb908fc45d 405 Pfam PF13527 Acetyltransferase (GNAT) domain 6 131 2.9E-19 T 28-03-2018 CU254_RS18325 06495c757037899b87b114bb908fc45d 405 Gene3D G3DSA:3.40.630.30 136 297 3.5E-41 T 28-03-2018 CU254_RS18325 06495c757037899b87b114bb908fc45d 405 Gene3D G3DSA:3.30.1050.10 298 399 1.9E-24 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CU254_RS18325 06495c757037899b87b114bb908fc45d 405 SUPERFAMILY SSF55718 304 405 2.43E-20 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CU254_RS27045 e6e7bde1f285268ec8f9b69e4c5a22c0 282 SUPERFAMILY SSF56112 20 271 4.67E-39 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS27045 e6e7bde1f285268ec8f9b69e4c5a22c0 282 Pfam PF03881 Fructosamine kinase 33 277 2.9E-42 T 28-03-2018 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 CU254_RS27045 e6e7bde1f285268ec8f9b69e4c5a22c0 282 PIRSF PIRSF006221 10 281 1.3E-54 T 28-03-2018 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 CU254_RS27045 e6e7bde1f285268ec8f9b69e4c5a22c0 282 Gene3D G3DSA:3.30.200.20 2 87 1.3E-10 T 28-03-2018 CU254_RS27045 e6e7bde1f285268ec8f9b69e4c5a22c0 282 Gene3D G3DSA:3.90.1200.10 88 277 2.0E-23 T 28-03-2018 CU254_RS23865 8f23ba7efcf7e8bb68bccf60a6718cdc 284 SUPERFAMILY SSF53474 2 280 2.01E-40 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS23865 8f23ba7efcf7e8bb68bccf60a6718cdc 284 Pfam PF00561 alpha/beta hydrolase fold 21 262 5.8E-11 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS23865 8f23ba7efcf7e8bb68bccf60a6718cdc 284 Gene3D G3DSA:3.40.50.1820 4 281 1.4E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS29780 98d0a1523f585888f0407fed6eb1ffb7 499 Pfam PF00171 Aldehyde dehydrogenase family 29 495 2.2E-178 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CU254_RS29780 98d0a1523f585888f0407fed6eb1ffb7 499 Gene3D G3DSA:3.40.605.10 10 287 1.5E-109 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CU254_RS29780 98d0a1523f585888f0407fed6eb1ffb7 499 Gene3D G3DSA:3.40.309.10 288 481 1.9E-73 T 28-03-2018 CU254_RS29780 98d0a1523f585888f0407fed6eb1ffb7 499 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 271 278 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CU254_RS29780 98d0a1523f585888f0407fed6eb1ffb7 499 SUPERFAMILY SSF53720 16 497 3.93E-172 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CU254_RS15585 41b91ec1752aafc8a79fddf7e60e90e1 198 SUPERFAMILY SSF53335 8 170 2.43E-27 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS15585 41b91ec1752aafc8a79fddf7e60e90e1 198 Pfam PF08241 Methyltransferase domain 40 129 3.4E-12 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CU254_RS15585 41b91ec1752aafc8a79fddf7e60e90e1 198 Gene3D G3DSA:3.40.50.150 1 189 6.0E-25 T 28-03-2018 CU254_RS12240 14bfe1d8a6a7616f2d0810896683bbfc 190 Gene3D G3DSA:3.40.50.1820 3 189 3.5E-9 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS12240 14bfe1d8a6a7616f2d0810896683bbfc 190 SUPERFAMILY SSF53474 31 140 4.39E-10 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS12240 14bfe1d8a6a7616f2d0810896683bbfc 190 Pfam PF01738 Dienelactone hydrolase family 40 142 5.6E-7 T 28-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 CU254_RS32245 d200fa334bb14b7865dc0ddf707711ad 381 Gene3D G3DSA:1.20.1250.20 1 174 8.7E-26 T 28-03-2018 CU254_RS32245 d200fa334bb14b7865dc0ddf707711ad 381 Pfam PF07690 Major Facilitator Superfamily 4 252 9.0E-32 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS32245 d200fa334bb14b7865dc0ddf707711ad 381 Gene3D G3DSA:1.20.1250.20 179 372 6.7E-33 T 28-03-2018 CU254_RS32245 d200fa334bb14b7865dc0ddf707711ad 381 SUPERFAMILY SSF103473 2 370 3.79E-65 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS41890 26a2fa6607b40c5a0538a79a02c729c5 321 Gene3D G3DSA:2.120.10.70 72 314 0.0015 T 28-03-2018 CU254_RS32625 2de3c1b03dca834059f38321b257ac1e 582 Gene3D G3DSA:3.40.190.10 193 339 8.7E-31 T 28-03-2018 CU254_RS32625 2de3c1b03dca834059f38321b257ac1e 582 Gene3D G3DSA:3.90.76.10 91 192 5.1E-14 T 28-03-2018 CU254_RS32625 2de3c1b03dca834059f38321b257ac1e 582 SUPERFAMILY SSF53850 61 578 4.34E-91 T 28-03-2018 CU254_RS32625 2de3c1b03dca834059f38321b257ac1e 582 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 116 501 1.7E-61 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CU254_RS32625 2de3c1b03dca834059f38321b257ac1e 582 Gene3D G3DSA:3.10.105.10 340 550 5.3E-49 T 28-03-2018 CU254_RS32625 2de3c1b03dca834059f38321b257ac1e 582 PIRSF PIRSF002741 32 581 3.8E-60 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CU254_RS12025 b89a72de260990812e079aa2619739e1 526 Pfam PF01039 Carboxyl transferase domain 41 514 1.3E-135 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 CU254_RS12025 b89a72de260990812e079aa2619739e1 526 Gene3D G3DSA:3.90.226.10 2 265 4.8E-57 T 28-03-2018 CU254_RS12025 b89a72de260990812e079aa2619739e1 526 Gene3D G3DSA:3.90.226.10 266 518 1.4E-58 T 28-03-2018 CU254_RS12025 b89a72de260990812e079aa2619739e1 526 SUPERFAMILY SSF52096 15 259 9.67E-62 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS12025 b89a72de260990812e079aa2619739e1 526 SUPERFAMILY SSF52096 267 515 5.83E-76 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS33985 9fe7a59a9dd27e43193791a906e2006b 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 53 1.0E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS33985 9fe7a59a9dd27e43193791a906e2006b 189 Gene3D G3DSA:1.10.10.60 2 30 7.1E-12 T 28-03-2018 CU254_RS33985 9fe7a59a9dd27e43193791a906e2006b 189 SUPERFAMILY SSF48498 75 184 2.81E-20 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS33985 9fe7a59a9dd27e43193791a906e2006b 189 Gene3D G3DSA:1.10.260.40 31 71 1.7E-10 T 28-03-2018 CU254_RS33985 9fe7a59a9dd27e43193791a906e2006b 189 SUPERFAMILY SSF46689 3 68 4.87E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS33985 9fe7a59a9dd27e43193791a906e2006b 189 Gene3D G3DSA:1.10.357.10 72 188 5.9E-18 T 28-03-2018 CU254_RS33985 9fe7a59a9dd27e43193791a906e2006b 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 51 3.6E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS33985 9fe7a59a9dd27e43193791a906e2006b 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 7 20 3.6E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS33985 9fe7a59a9dd27e43193791a906e2006b 189 Pfam PF13305 WHG domain 79 165 5.9E-17 T 28-03-2018 IPR025996 WHG domain CU254_RS01180 ae6631ff5da5994794ec6db278470334 416 Gene3D G3DSA:2.40.50.100 156 352 9.8E-4 T 28-03-2018 CU254_RS01180 ae6631ff5da5994794ec6db278470334 416 SUPERFAMILY SSF111369 70 190 2.88E-12 T 28-03-2018 CU254_RS01180 ae6631ff5da5994794ec6db278470334 416 Pfam PF13437 HlyD family secretion protein 225 300 4.3E-8 T 28-03-2018 CU254_RS01180 ae6631ff5da5994794ec6db278470334 416 Gene3D G3DSA:2.40.50.100 70 127 4.6E-13 T 28-03-2018 CU254_RS01180 ae6631ff5da5994794ec6db278470334 416 Pfam PF13533 Biotin-lipoyl like 73 114 1.4E-10 T 28-03-2018 CU254_RS09815 41c547f64d597a5d3de6f77556217bd3 301 Pfam PF04228 Putative neutral zinc metallopeptidase 105 292 3.5E-14 T 28-03-2018 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative CU254_RS28205 09970b80c79b34e844ed831224a4ef2b 327 SMART SM00481 97 176 1.3E-18 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CU254_RS28205 09970b80c79b34e844ed831224a4ef2b 327 SUPERFAMILY SSF89550 96 325 1.11E-49 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CU254_RS28205 09970b80c79b34e844ed831224a4ef2b 327 PIRSF PIRSF036978 1 327 1.1E-152 T 28-03-2018 IPR017078 Uncharacterised conserved protein UCP036978, histidinol phosphatase-related hydrolase, SCO0789 CU254_RS28205 09970b80c79b34e844ed831224a4ef2b 327 Gene3D G3DSA:3.20.20.140 97 326 1.3E-51 T 28-03-2018 CU254_RS28205 09970b80c79b34e844ed831224a4ef2b 327 Pfam PF02811 PHP domain 98 184 1.1E-6 T 28-03-2018 IPR004013 PHP domain GO:0003824 CU254_RS28205 09970b80c79b34e844ed831224a4ef2b 327 SUPERFAMILY SSF47802 3 80 1.26E-12 T 28-03-2018 IPR010996 DNA polymerase beta-like, N-terminal domain CU254_RS28205 09970b80c79b34e844ed831224a4ef2b 327 Gene3D G3DSA:1.10.150.110 2 83 6.2E-13 T 28-03-2018 CU254_RS28205 09970b80c79b34e844ed831224a4ef2b 327 Pfam PF14716 Helix-hairpin-helix domain 4 67 5.2E-14 T 28-03-2018 IPR010996 DNA polymerase beta-like, N-terminal domain CU254_RS14955 662295c83ae58908b0a83a022c40c1f3 479 Pfam PF00171 Aldehyde dehydrogenase family 18 475 2.6E-154 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CU254_RS14955 662295c83ae58908b0a83a022c40c1f3 479 Gene3D G3DSA:3.40.309.10 267 460 1.0E-70 T 28-03-2018 CU254_RS14955 662295c83ae58908b0a83a022c40c1f3 479 SUPERFAMILY SSF53720 8 478 2.49E-154 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CU254_RS14955 662295c83ae58908b0a83a022c40c1f3 479 Gene3D G3DSA:3.40.605.10 2 266 3.4E-83 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CU254_RS14955 662295c83ae58908b0a83a022c40c1f3 479 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 276 287 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CU254_RS02005 40db9e0baedfc765fb2c0317d97b6e71 104 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 1 104 6.6E-38 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS02005 40db9e0baedfc765fb2c0317d97b6e71 104 ProSitePatterns PS01108 Ribosomal protein L24 signature. 6 23 - T 28-03-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS02005 40db9e0baedfc765fb2c0317d97b6e71 104 Pfam PF00467 KOW motif 5 36 1.4E-9 T 28-03-2018 IPR005824 KOW CU254_RS02005 40db9e0baedfc765fb2c0317d97b6e71 104 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 104 1.0E-26 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS02005 40db9e0baedfc765fb2c0317d97b6e71 104 Gene3D G3DSA:2.30.30.30 1 95 1.1E-33 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 CU254_RS02005 40db9e0baedfc765fb2c0317d97b6e71 104 SMART SM00739 2 29 1.6E-5 T 28-03-2018 IPR005824 KOW CU254_RS02005 40db9e0baedfc765fb2c0317d97b6e71 104 SUPERFAMILY SSF50104 1 101 3.57E-32 T 28-03-2018 IPR008991 Translation protein SH3-like domain CU254_RS02005 40db9e0baedfc765fb2c0317d97b6e71 104 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 1 98 22.051 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS01910 64ba67b7fd6cecfe46c663913f204efd 163 Pfam PF05423 Mycobacterium membrane protein 75 145 1.3E-6 T 28-03-2018 IPR008693 Transport accessory protein MmpS CU254_RS36625 4fb83b8617ebd9c600e30d48d130fbe0 165 SUPERFAMILY SSF53271 8 151 1.66E-24 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CU254_RS36625 4fb83b8617ebd9c600e30d48d130fbe0 165 Pfam PF00156 Phosphoribosyl transferase domain 15 151 2.8E-18 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CU254_RS36625 4fb83b8617ebd9c600e30d48d130fbe0 165 Gene3D G3DSA:3.40.50.2020 2 158 1.8E-24 T 28-03-2018 CU254_RS21200 0830027d5c242f94b8dc0dd21135e50f 495 SUPERFAMILY SSF52743 143 488 2.49E-62 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS21200 0830027d5c242f94b8dc0dd21135e50f 495 Gene3D G3DSA:3.40.50.200 139 494 1.1E-35 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS21200 0830027d5c242f94b8dc0dd21135e50f 495 SMART SM00944 1 126 2.7E-19 T 28-03-2018 IPR015366 Peptidase S53, activation domain GO:0008236 Reactome: R-HSA-381038 CU254_RS21200 0830027d5c242f94b8dc0dd21135e50f 495 Pfam PF09286 Pro-kumamolisin, activation domain 32 125 2.2E-11 T 28-03-2018 IPR015366 Peptidase S53, activation domain GO:0008236 Reactome: R-HSA-381038 CU254_RS21200 0830027d5c242f94b8dc0dd21135e50f 495 SUPERFAMILY SSF54897 2 137 1.33E-28 T 28-03-2018 IPR009020 Protease propeptides/proteinase inhibitor I9 CU254_RS28270 a8074cbf504f9fd30830b6a745490192 161 SUPERFAMILY SSF47741 85 153 1.24E-29 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CU254_RS28270 a8074cbf504f9fd30830b6a745490192 161 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 40 48 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CU254_RS28270 a8074cbf504f9fd30830b6a745490192 161 Gene3D G3DSA:1.10.150.120 76 159 4.7E-33 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CU254_RS28270 a8074cbf504f9fd30830b6a745490192 161 Gene3D G3DSA:3.10.20.30 1 75 7.0E-22 T 28-03-2018 IPR012675 Beta-grasp domain CU254_RS28270 a8074cbf504f9fd30830b6a745490192 161 Pfam PF01799 [2Fe-2S] binding domain 74 146 8.6E-29 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CU254_RS28270 a8074cbf504f9fd30830b6a745490192 161 SUPERFAMILY SSF54292 2 79 6.16E-21 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CU254_RS28270 a8074cbf504f9fd30830b6a745490192 161 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 6 55 8.3E-7 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CU254_RS32930 65f08745abcc735076aec6c655f65f0e 304 TIGRFAM TIGR03446 mycothiol_Mca: mycothiol conjugate amidase Mca 16 298 3.2E-156 T 28-03-2018 IPR017811 Mycothiol S-conjugate amidase Mca GO:0010126 KEGG: 00311+3.5.1.11 CU254_RS32930 65f08745abcc735076aec6c655f65f0e 304 Pfam PF02585 GlcNAc-PI de-N-acetylase 19 164 6.4E-29 T 28-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 CU254_RS32930 65f08745abcc735076aec6c655f65f0e 304 Gene3D G3DSA:3.40.50.10320 12 304 2.3E-78 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CU254_RS32930 65f08745abcc735076aec6c655f65f0e 304 SUPERFAMILY SSF102588 16 298 5.75E-82 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CU254_RS32930 65f08745abcc735076aec6c655f65f0e 304 Hamap MF_01482 Mycothiol S-conjugate amidase [mca]. 19 299 54.669 T 28-03-2018 IPR017811 Mycothiol S-conjugate amidase Mca GO:0010126 KEGG: 00311+3.5.1.11 CU254_RS15100 b55553875173562c0f6ac2292ed2b127 105 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 53 68 9.6E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS15100 b55553875173562c0f6ac2292ed2b127 105 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 6 21 9.6E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS15100 b55553875173562c0f6ac2292ed2b127 105 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 38 53 9.6E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS15100 b55553875173562c0f6ac2292ed2b127 105 Pfam PF12840 Helix-turn-helix domain 3 62 1.5E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS15100 b55553875173562c0f6ac2292ed2b127 105 SMART SM00418 4 82 5.3E-22 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS15100 b55553875173562c0f6ac2292ed2b127 105 Gene3D G3DSA:1.10.10.10 2 105 4.0E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS15100 b55553875173562c0f6ac2292ed2b127 105 SUPERFAMILY SSF46785 3 95 2.14E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS02405 0e655258fae61c72ededbf05f781e9e3 198 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 137 151 8.7E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS02405 0e655258fae61c72ededbf05f781e9e3 198 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 167 8.7E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS02405 0e655258fae61c72ededbf05f781e9e3 198 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 179 8.7E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS02405 0e655258fae61c72ededbf05f781e9e3 198 SUPERFAMILY SSF52172 3 123 1.42E-16 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS02405 0e655258fae61c72ededbf05f781e9e3 198 ProSitePatterns PS00622 LuxR-type HTH domain signature. 151 178 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS02405 0e655258fae61c72ededbf05f781e9e3 198 Pfam PF00072 Response regulator receiver domain 4 115 2.2E-12 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS02405 0e655258fae61c72ededbf05f781e9e3 198 Gene3D G3DSA:1.10.10.10 127 198 9.8E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS02405 0e655258fae61c72ededbf05f781e9e3 198 SUPERFAMILY SSF46894 125 197 1.94E-21 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS02405 0e655258fae61c72ededbf05f781e9e3 198 SMART SM00421 134 191 6.1E-25 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS02405 0e655258fae61c72ededbf05f781e9e3 198 Gene3D G3DSA:3.40.50.2300 1 124 1.3E-20 T 28-03-2018 CU254_RS02405 0e655258fae61c72ededbf05f781e9e3 198 Pfam PF00196 Bacterial regulatory proteins, luxR family 136 189 2.2E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS02405 0e655258fae61c72ededbf05f781e9e3 198 SMART SM00448 2 115 5.3E-7 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS29915 df58b39c2628d09fcf1fa27a715706d1 139 Gene3D G3DSA:1.10.10.10 14 97 2.4E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS29915 df58b39c2628d09fcf1fa27a715706d1 139 SUPERFAMILY SSF46785 15 121 1.68E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS29915 df58b39c2628d09fcf1fa27a715706d1 139 Pfam PF01475 Ferric uptake regulator family 21 118 8.0E-12 T 28-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CU254_RS17765 0f6f0c5fecda111b309da38c57ed9cc0 446 Gene3D G3DSA:3.40.50.2000 266 427 5.9E-46 T 28-03-2018 CU254_RS17765 0f6f0c5fecda111b309da38c57ed9cc0 446 SUPERFAMILY SSF53756 65 444 1.1E-80 T 28-03-2018 CU254_RS17765 0f6f0c5fecda111b309da38c57ed9cc0 446 Pfam PF00534 Glycosyl transferases group 1 269 420 4.3E-36 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CU254_RS17765 0f6f0c5fecda111b309da38c57ed9cc0 446 Pfam PF13439 Glycosyltransferase Family 4 68 257 3.3E-27 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CU254_RS17765 0f6f0c5fecda111b309da38c57ed9cc0 446 Gene3D G3DSA:3.40.50.2000 53 265 1.1E-21 T 28-03-2018 CU254_RS20425 2e9d36d5ef0a18eb9b4abea4fc832432 384 SUPERFAMILY SSF51679 6 366 5.76E-95 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS20425 2e9d36d5ef0a18eb9b4abea4fc832432 384 Gene3D G3DSA:3.20.20.30 1 371 2.5E-92 T 28-03-2018 CU254_RS20425 2e9d36d5ef0a18eb9b4abea4fc832432 384 Pfam PF00296 Luciferase-like monooxygenase 4 336 3.1E-89 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS02645 cd809b19833d7ec1d38ab02d06ae97e1 1110 SUPERFAMILY SSF89550 196 279 5.3E-21 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CU254_RS02645 cd809b19833d7ec1d38ab02d06ae97e1 1110 SUPERFAMILY SSF89550 60 149 5.3E-21 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CU254_RS02645 cd809b19833d7ec1d38ab02d06ae97e1 1110 Gene3D G3DSA:2.40.50.140 1008 1100 1.1E-7 T 28-03-2018 CU254_RS02645 cd809b19833d7ec1d38ab02d06ae97e1 1110 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 361 778 1.6E-146 T 28-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CU254_RS02645 cd809b19833d7ec1d38ab02d06ae97e1 1110 SMART SM00481 61 128 7.7E-25 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CU254_RS02645 cd809b19833d7ec1d38ab02d06ae97e1 1110 Gene3D G3DSA:1.10.150.280 865 940 1.1E-6 T 28-03-2018 CU254_RS02645 cd809b19833d7ec1d38ab02d06ae97e1 1110 Pfam PF02811 PHP domain 62 241 5.8E-26 T 28-03-2018 IPR004013 PHP domain GO:0003824 CU254_RS02645 cd809b19833d7ec1d38ab02d06ae97e1 1110 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 61 950 4.5E-204 T 28-03-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CU254_RS02645 cd809b19833d7ec1d38ab02d06ae97e1 1110 Gene3D G3DSA:3.20.20.140 58 321 1.1E-41 T 28-03-2018 CU254_RS02645 cd809b19833d7ec1d38ab02d06ae97e1 1110 Pfam PF14579 Helix-hairpin-helix motif 851 944 5.1E-24 T 28-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CU254_RS02645 cd809b19833d7ec1d38ab02d06ae97e1 1110 Hamap MF_01902 Error-prone DNA polymerase [dnaE2]. 60 1110 12.523 T 28-03-2018 IPR023073 DNA polymerase, error-prone GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CU254_RS26480 73fd388c9021a27110e768b90b4169ac 106 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 5 98 1.0E-7 T 28-03-2018 IPR022536 ESX-1 secretion-associated protein EspC GO:0009306 CU254_RS26480 73fd388c9021a27110e768b90b4169ac 106 Gene3D G3DSA:1.10.287.1060 1 100 8.2E-6 T 28-03-2018 CU254_RS34620 bf05bd8e6462a458fe41532e14389f23 249 Gene3D G3DSA:3.20.20.370 1 247 1.0E-105 T 28-03-2018 CU254_RS34620 bf05bd8e6462a458fe41532e14389f23 249 Pfam PF03746 LamB/YcsF family 1 238 6.4E-101 T 28-03-2018 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF CU254_RS34620 bf05bd8e6462a458fe41532e14389f23 249 SUPERFAMILY SSF88713 1 248 4.08E-97 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CU254_RS34620 bf05bd8e6462a458fe41532e14389f23 249 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 1 243 43.141 T 28-03-2018 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF CU254_RS21560 b0e2fb3fce01e3450d2f6607c6fd0ab1 105 Pfam PF13411 MerR HTH family regulatory protein 15 79 1.5E-11 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS21560 b0e2fb3fce01e3450d2f6607c6fd0ab1 105 SMART SM00422 15 83 7.9E-5 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS21560 b0e2fb3fce01e3450d2f6607c6fd0ab1 105 SUPERFAMILY SSF46955 15 103 5.49E-12 T 28-03-2018 IPR009061 Putative DNA-binding domain CU254_RS21560 b0e2fb3fce01e3450d2f6607c6fd0ab1 105 Gene3D G3DSA:1.10.1660.10 4 104 1.6E-17 T 28-03-2018 CU254_RS17350 cb3bc8ee202d78c127d3a98171fae254 469 Gene3D G3DSA:3.90.1150.10 354 469 3.4E-10 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS17350 cb3bc8ee202d78c127d3a98171fae254 469 Pfam PF00266 Aminotransferase class-V 108 373 1.2E-33 T 28-03-2018 IPR000192 Aminotransferase class V domain CU254_RS17350 cb3bc8ee202d78c127d3a98171fae254 469 Gene3D G3DSA:3.40.640.10 86 353 2.7E-34 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS17350 cb3bc8ee202d78c127d3a98171fae254 469 SUPERFAMILY SSF53383 56 467 1.5E-63 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS33845 e7544d1e8ebb153f1ede0f7c84f278bf 274 PIRSF PIRSF005902 12 274 1.2E-72 T 28-03-2018 IPR001130 TatD family GO:0016788 CU254_RS33845 e7544d1e8ebb153f1ede0f7c84f278bf 274 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 19 271 2.9E-78 T 28-03-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 CU254_RS33845 e7544d1e8ebb153f1ede0f7c84f278bf 274 Gene3D G3DSA:3.20.20.140 17 274 3.0E-78 T 28-03-2018 CU254_RS33845 e7544d1e8ebb153f1ede0f7c84f278bf 274 SUPERFAMILY SSF51556 18 272 2.51E-76 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS33845 e7544d1e8ebb153f1ede0f7c84f278bf 274 Pfam PF01026 TatD related DNase 20 271 1.3E-69 T 28-03-2018 IPR001130 TatD family GO:0016788 CU254_RS02220 93db3466db8188d8594396d8058f52eb 880 Gene3D G3DSA:1.10.287.850 184 275 4.3E-8 T 28-03-2018 CU254_RS02220 93db3466db8188d8594396d8058f52eb 880 Gene3D G3DSA:1.20.120.20 305 517 0.36 T 28-03-2018 CU254_RS02220 93db3466db8188d8594396d8058f52eb 880 SUPERFAMILY SSF140453 190 259 6.15E-6 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CU254_RS30225 b5c633c6c0651e42da7dd4c7cb87c9c6 228 Gene3D G3DSA:3.40.630.30 34 226 6.7E-24 T 28-03-2018 CU254_RS30225 b5c633c6c0651e42da7dd4c7cb87c9c6 228 Pfam PF08445 FR47-like protein 134 216 5.4E-24 T 28-03-2018 IPR013653 FR47-like GO:0016747 CU254_RS30225 b5c633c6c0651e42da7dd4c7cb87c9c6 228 SUPERFAMILY SSF55729 99 217 1.26E-21 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS11930 a820b6ddcc62982a202941aab5327fd6 417 Gene3D G3DSA:3.40.50.150 138 415 3.5E-59 T 28-03-2018 CU254_RS11930 a820b6ddcc62982a202941aab5327fd6 417 SUPERFAMILY SSF53335 151 413 4.6E-64 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS11930 a820b6ddcc62982a202941aab5327fd6 417 Pfam PF02353 Mycolic acid cyclopropane synthetase 145 411 1.2E-84 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS11930 a820b6ddcc62982a202941aab5327fd6 417 PIRSF PIRSF003085 32 417 6.6E-115 T 28-03-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 CU254_RS23480 3ec538b06542b6f7bfbb3bf4cc9ab026 288 SUPERFAMILY SSF47240 1 270 9.42E-89 T 28-03-2018 IPR009078 Ferritin-like superfamily CU254_RS23480 3ec538b06542b6f7bfbb3bf4cc9ab026 288 Gene3D G3DSA:3.30.1530.10 209 264 2.8E-7 T 28-03-2018 IPR027407 Manganese catalase, domain 2 CU254_RS23480 3ec538b06542b6f7bfbb3bf4cc9ab026 288 Pfam PF05067 Manganese containing catalase 1 257 1.1E-91 T 28-03-2018 IPR007760 Manganese catalase CU254_RS23480 3ec538b06542b6f7bfbb3bf4cc9ab026 288 Gene3D G3DSA:1.20.1260.10 1 198 7.2E-68 T 28-03-2018 IPR012347 Ferritin-related CU254_RS03145 caf90444483648929dc7870550b74fa6 428 PIRSF PIRSF005962 46 428 3.0E-99 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CU254_RS03145 caf90444483648929dc7870550b74fa6 428 SUPERFAMILY SSF55031 222 339 9.42E-19 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CU254_RS03145 caf90444483648929dc7870550b74fa6 428 SUPERFAMILY SSF53187 47 237 3.59E-68 T 28-03-2018 CU254_RS03145 caf90444483648929dc7870550b74fa6 428 SUPERFAMILY SSF53187 338 426 3.59E-68 T 28-03-2018 CU254_RS03145 caf90444483648929dc7870550b74fa6 428 Pfam PF01546 Peptidase family M20/M25/M40 113 423 5.2E-27 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CU254_RS03145 caf90444483648929dc7870550b74fa6 428 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 59 415 3.2E-96 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CU254_RS03145 caf90444483648929dc7870550b74fa6 428 Gene3D G3DSA:3.40.630.10 45 275 3.6E-44 T 28-03-2018 CU254_RS03145 caf90444483648929dc7870550b74fa6 428 Gene3D G3DSA:3.40.630.10 276 428 1.4E-17 T 28-03-2018 CU254_RS30665 e679b39c1b8446e2e7d9be662b3d90e8 345 Gene3D G3DSA:3.20.20.30 1 343 1.4E-66 T 28-03-2018 CU254_RS30665 e679b39c1b8446e2e7d9be662b3d90e8 345 SUPERFAMILY SSF51679 9 341 5.74E-65 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS30665 e679b39c1b8446e2e7d9be662b3d90e8 345 Pfam PF00296 Luciferase-like monooxygenase 7 316 4.2E-75 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS26485 82fef9aeeca69c8ff6fea1d65f5720ca 410 Gene3D G3DSA:1.20.120.20 219 400 0.013 T 28-03-2018 CU254_RS26485 82fef9aeeca69c8ff6fea1d65f5720ca 410 Gene3D G3DSA:1.10.287.850 99 187 2.1E-11 T 28-03-2018 CU254_RS26485 82fef9aeeca69c8ff6fea1d65f5720ca 410 SUPERFAMILY SSF140459 109 180 4.71E-6 T 28-03-2018 CU254_RS27030 a4a998fc2dbdc7766719a2ffae54ffe1 217 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 130 143 - T 28-03-2018 IPR033135 ClpP, histidine active site CU254_RS27030 a4a998fc2dbdc7766719a2ffae54ffe1 217 Gene3D G3DSA:3.90.226.10 20 213 1.2E-38 T 28-03-2018 CU254_RS27030 a4a998fc2dbdc7766719a2ffae54ffe1 217 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 108 119 - T 28-03-2018 IPR018215 ClpP, Ser active site CU254_RS27030 a4a998fc2dbdc7766719a2ffae54ffe1 217 Pfam PF00574 Clp protease 36 209 9.1E-76 T 28-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA CU254_RS27030 a4a998fc2dbdc7766719a2ffae54ffe1 217 PRINTS PR00127 Clp protease catalytic subunit P signature 37 52 1.0E-41 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CU254_RS27030 a4a998fc2dbdc7766719a2ffae54ffe1 217 PRINTS PR00127 Clp protease catalytic subunit P signature 77 97 1.0E-41 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CU254_RS27030 a4a998fc2dbdc7766719a2ffae54ffe1 217 PRINTS PR00127 Clp protease catalytic subunit P signature 108 125 1.0E-41 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CU254_RS27030 a4a998fc2dbdc7766719a2ffae54ffe1 217 PRINTS PR00127 Clp protease catalytic subunit P signature 187 206 1.0E-41 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CU254_RS27030 a4a998fc2dbdc7766719a2ffae54ffe1 217 PRINTS PR00127 Clp protease catalytic subunit P signature 129 148 1.0E-41 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CU254_RS27030 a4a998fc2dbdc7766719a2ffae54ffe1 217 SUPERFAMILY SSF52096 29 214 3.11E-62 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS27030 a4a998fc2dbdc7766719a2ffae54ffe1 217 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 21 212 39.067 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CU254_RS04760 1cb593538bd1df06a8c9325faee1ec4b 115 ProSitePatterns PS00354 HMG-I and HMG-Y DNA-binding domain (A+T-hook). 90 100 - T 28-03-2018 IPR000637 HMG-I/HMG-Y, DNA-binding, conserved site GO:0006355 CU254_RS04760 1cb593538bd1df06a8c9325faee1ec4b 115 Pfam PF02178 AT hook motif 92 102 0.0039 T 28-03-2018 IPR017956 AT hook, DNA-binding motif GO:0003677 CU254_RS04760 1cb593538bd1df06a8c9325faee1ec4b 115 Pfam PF02467 Transcription factor WhiB 32 80 2.9E-16 T 28-03-2018 IPR034768 WhiB-like iron-sulfur binding domain CU254_RS04760 1cb593538bd1df06a8c9325faee1ec4b 115 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 94 15.997 T 28-03-2018 IPR003482 Transcription factor WhiB CU254_RS06955 8ac3961f0f9fb08b9ca0a98f87fa605b 256 SUPERFAMILY SSF56529 50 253 6.15E-77 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CU254_RS06955 8ac3961f0f9fb08b9ca0a98f87fa605b 256 Pfam PF10370 Domain of unknown function (DUF2437) 2 54 3.3E-16 T 28-03-2018 IPR018833 Domain of unknown function DUF2437 CU254_RS06955 8ac3961f0f9fb08b9ca0a98f87fa605b 256 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 59 253 9.9E-66 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CU254_RS06955 8ac3961f0f9fb08b9ca0a98f87fa605b 256 Gene3D G3DSA:3.90.850.10 28 256 2.8E-86 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CU254_RS19825 385427ffc55aaccaf67909f3a0aaf679 152 Gene3D G3DSA:2.40.50.140 1 120 7.0E-40 T 28-03-2018 CU254_RS19825 385427ffc55aaccaf67909f3a0aaf679 152 SUPERFAMILY SSF50249 6 152 3.86E-42 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CU254_RS19825 385427ffc55aaccaf67909f3a0aaf679 152 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 6 122 3.7E-32 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CU254_RS19825 385427ffc55aaccaf67909f3a0aaf679 152 Pfam PF00436 Single-strand binding protein family 7 106 2.7E-29 T 28-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 CU254_RS19825 385427ffc55aaccaf67909f3a0aaf679 152 Hamap MF_00984 Single-stranded DNA-binding protein. 4 113 30.383 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CU254_RS12610 ba921967215736fbe8e0102ff9ceb5ed 295 Pfam PF01183 Glycosyl hydrolases family 25 31 174 4.4E-10 T 28-03-2018 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 CU254_RS12610 ba921967215736fbe8e0102ff9ceb5ed 295 SUPERFAMILY SSF51445 42 187 1.61E-17 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS12610 ba921967215736fbe8e0102ff9ceb5ed 295 Gene3D G3DSA:3.20.20.80 6 199 2.5E-25 T 28-03-2018 CU254_RS29585 878079279f4d5c777a4be1c97ea11cd1 350 Gene3D G3DSA:4.10.1270.10 291 350 1.1E-32 T 28-03-2018 CU254_RS29585 878079279f4d5c777a4be1c97ea11cd1 350 SUPERFAMILY SSF54593 4 319 9.07E-45 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS29585 878079279f4d5c777a4be1c97ea11cd1 350 TIGRFAM TIGR02295 HpaD: 3,4-dihydroxyphenylacetate 2,3-dioxygenase 7 302 5.4E-130 T 28-03-2018 IPR011981 3,4-dihydroxyphenylacetate 2,3-dioxygenase, Mn/Fe-type CU254_RS29585 878079279f4d5c777a4be1c97ea11cd1 350 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 12 121 3.4E-6 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CU254_RS29585 878079279f4d5c777a4be1c97ea11cd1 350 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 145 261 5.5E-15 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CU254_RS29585 878079279f4d5c777a4be1c97ea11cd1 350 Gene3D G3DSA:3.10.180.10 6 140 5.2E-18 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS29585 878079279f4d5c777a4be1c97ea11cd1 350 ProSitePatterns PS00082 Extradiol ring-cleavage dioxygenases signature. 239 260 - T 28-03-2018 IPR000486 Extradiol ring-cleavage dioxygenase, class I /II GO:0003824|GO:0006725|GO:0008198|GO:0055114 CU254_RS29585 878079279f4d5c777a4be1c97ea11cd1 350 Gene3D G3DSA:3.10.180.10 141 290 1.2E-27 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS25015 8c492b2bb0700fb3817c171e7d50b45f 225 SUPERFAMILY SSF55781 79 224 5.69E-21 T 28-03-2018 IPR029016 GAF domain-like CU254_RS25015 8c492b2bb0700fb3817c171e7d50b45f 225 SMART SM00346 7 94 1.0E-14 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS25015 8c492b2bb0700fb3817c171e7d50b45f 225 SUPERFAMILY SSF46785 8 76 3.23E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS25015 8c492b2bb0700fb3817c171e7d50b45f 225 Pfam PF09339 IclR helix-turn-helix domain 10 59 2.6E-12 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS25015 8c492b2bb0700fb3817c171e7d50b45f 225 Gene3D G3DSA:3.30.450.40 77 154 8.8E-12 T 28-03-2018 IPR029016 GAF domain-like CU254_RS25015 8c492b2bb0700fb3817c171e7d50b45f 225 Gene3D G3DSA:3.30.450.40 155 225 7.5E-8 T 28-03-2018 IPR029016 GAF domain-like CU254_RS25015 8c492b2bb0700fb3817c171e7d50b45f 225 Gene3D G3DSA:1.10.10.10 7 67 4.5E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS31390 41569649a18bb6f98438c9725f034ef4 424 PIRSF PIRSF000098 1 422 5.2E-152 T 28-03-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CU254_RS31390 41569649a18bb6f98438c9725f034ef4 424 Gene3D G3DSA:3.40.50.720 1 139 1.4E-25 T 28-03-2018 CU254_RS31390 41569649a18bb6f98438c9725f034ef4 424 Gene3D G3DSA:3.30.70.260 340 418 3.2E-20 T 28-03-2018 CU254_RS31390 41569649a18bb6f98438c9725f034ef4 424 Gene3D G3DSA:3.30.360.10 140 295 2.2E-57 T 28-03-2018 CU254_RS31390 41569649a18bb6f98438c9725f034ef4 424 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 174 196 - T 28-03-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CU254_RS31390 41569649a18bb6f98438c9725f034ef4 424 Pfam PF00742 Homoserine dehydrogenase 128 311 2.6E-65 T 28-03-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CU254_RS31390 41569649a18bb6f98438c9725f034ef4 424 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 3 120 4.9E-25 T 28-03-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 CU254_RS31390 41569649a18bb6f98438c9725f034ef4 424 SUPERFAMILY SSF51735 1 149 2.23E-31 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS31390 41569649a18bb6f98438c9725f034ef4 424 SUPERFAMILY SSF55021 341 414 4.85E-13 T 28-03-2018 CU254_RS31390 41569649a18bb6f98438c9725f034ef4 424 SUPERFAMILY SSF55347 128 298 3.2E-50 T 28-03-2018 CU254_RS31390 41569649a18bb6f98438c9725f034ef4 424 Pfam PF01842 ACT domain 346 408 2.7E-12 T 28-03-2018 IPR002912 ACT domain CU254_RS39115 42853171348b7e7cc515ab46499d13c8 630 Pfam PF14021 Tuberculosis necrotizing toxin 546 629 2.0E-20 T 28-03-2018 IPR025331 Tuberculosis necrotizing toxin CU254_RS39115 42853171348b7e7cc515ab46499d13c8 630 SUPERFAMILY SSF160424 150 278 4.18E-13 T 28-03-2018 IPR006728 Protein of unknown function DUF600 CU254_RS05335 3c4e13aa6b2ae715be85ed725db6d1a6 225 SUPERFAMILY SSF46689 17 88 1.55E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS05335 3c4e13aa6b2ae715be85ed725db6d1a6 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 42 1.4E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS05335 3c4e13aa6b2ae715be85ed725db6d1a6 225 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 50 73 1.4E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS05335 3c4e13aa6b2ae715be85ed725db6d1a6 225 Gene3D G3DSA:1.10.357.10 71 213 5.1E-16 T 28-03-2018 CU254_RS05335 3c4e13aa6b2ae715be85ed725db6d1a6 225 Gene3D G3DSA:1.10.10.60 9 70 5.4E-18 T 28-03-2018 CU254_RS05335 3c4e13aa6b2ae715be85ed725db6d1a6 225 Pfam PF00440 Bacterial regulatory proteins, tetR family 29 72 6.6E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS16700 84787f7dd867d8bbfb4d21b3967ec203 324 SUPERFAMILY SSF161098 86 311 2.09E-60 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS16700 84787f7dd867d8bbfb4d21b3967ec203 324 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 121 320 4.6E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS16700 84787f7dd867d8bbfb4d21b3967ec203 324 Gene3D G3DSA:1.10.3720.10 44 324 1.3E-49 T 28-03-2018 CU254_RS10670 e30a2d9d80b74c6db92f61ca683af5d4 145 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 4 139 4.1E-13 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase CU254_RS10670 e30a2d9d80b74c6db92f61ca683af5d4 145 Gene3D G3DSA:3.30.530.20 1 142 1.2E-22 T 28-03-2018 IPR023393 START-like domain CU254_RS10670 e30a2d9d80b74c6db92f61ca683af5d4 145 SUPERFAMILY SSF55961 1 139 1.47E-21 T 28-03-2018 CU254_RS39700 bf8701cd7b87f47e1664f51be38d7172 419 SUPERFAMILY SSF103473 24 416 1.1E-48 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS39700 bf8701cd7b87f47e1664f51be38d7172 419 Pfam PF07690 Major Facilitator Superfamily 45 277 1.4E-19 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS39700 bf8701cd7b87f47e1664f51be38d7172 419 Gene3D G3DSA:1.20.1250.20 13 212 1.1E-21 T 28-03-2018 CU254_RS39700 bf8701cd7b87f47e1664f51be38d7172 419 Pfam PF06779 Uncharacterised MFS-type transporter YbfB 281 412 1.9E-8 T 28-03-2018 IPR010645 Uncharacterised MFS-type transporter YbfB CU254_RS39700 bf8701cd7b87f47e1664f51be38d7172 419 Gene3D G3DSA:1.20.1250.20 226 417 1.7E-29 T 28-03-2018 CU254_RS02095 29333fe07b6b626d651ba1a69041e8f4 201 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 201 3.2E-76 T 28-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 CU254_RS02095 29333fe07b6b626d651ba1a69041e8f4 201 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 90 1.5E-28 T 28-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CU254_RS02095 29333fe07b6b626d651ba1a69041e8f4 201 Pfam PF01479 S4 domain 92 137 2.3E-18 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CU254_RS02095 29333fe07b6b626d651ba1a69041e8f4 201 Gene3D G3DSA:1.10.1050.10 1 96 7.2E-39 T 28-03-2018 CU254_RS02095 29333fe07b6b626d651ba1a69041e8f4 201 SUPERFAMILY SSF55174 3 201 2.75E-65 T 28-03-2018 CU254_RS02095 29333fe07b6b626d651ba1a69041e8f4 201 Gene3D G3DSA:3.10.290.10 97 141 1.9E-15 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CU254_RS02095 29333fe07b6b626d651ba1a69041e8f4 201 Gene3D G3DSA:1.10.1050.10 142 201 1.0E-11 T 28-03-2018 CU254_RS02095 29333fe07b6b626d651ba1a69041e8f4 201 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 201 34.34 T 28-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 CU254_RS02095 29333fe07b6b626d651ba1a69041e8f4 201 SMART SM01390 3 90 5.7E-42 T 28-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CU254_RS02095 29333fe07b6b626d651ba1a69041e8f4 201 ProSitePatterns PS00632 Ribosomal protein S4 signature. 89 113 - T 28-03-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS02095 29333fe07b6b626d651ba1a69041e8f4 201 SMART SM00363 91 156 2.1E-14 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CU254_RS38770 e605d287e1bf91aa00a65d9bd8187990 514 Pfam PF00350 Dynamin family 50 202 8.6E-12 T 28-03-2018 IPR022812 Dynamin superfamily CU254_RS38770 e605d287e1bf91aa00a65d9bd8187990 514 SUPERFAMILY SSF52540 45 236 1.61E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS38770 e605d287e1bf91aa00a65d9bd8187990 514 Gene3D G3DSA:3.40.50.300 49 280 8.0E-30 T 28-03-2018 CU254_RS03380 baeb1fad4b32f1292a53bd5fad752d35 259 SUPERFAMILY SSF56784 28 235 1.13E-38 T 28-03-2018 IPR023214 HAD-like domain CU254_RS03380 baeb1fad4b32f1292a53bd5fad752d35 259 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 151 167 4.9E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CU254_RS03380 baeb1fad4b32f1292a53bd5fad752d35 259 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 27 38 4.9E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CU254_RS03380 baeb1fad4b32f1292a53bd5fad752d35 259 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 120 133 4.9E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CU254_RS03380 baeb1fad4b32f1292a53bd5fad752d35 259 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 198 211 4.9E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CU254_RS03380 baeb1fad4b32f1292a53bd5fad752d35 259 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 121 203 2.2E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CU254_RS03380 baeb1fad4b32f1292a53bd5fad752d35 259 Pfam PF13419 Haloacid dehalogenase-like hydrolase 31 209 4.8E-22 T 28-03-2018 IPR023214 HAD-like domain CU254_RS03380 baeb1fad4b32f1292a53bd5fad752d35 259 Gene3D G3DSA:3.40.50.1000 88 243 7.8E-31 T 28-03-2018 IPR023214 HAD-like domain CU254_RS07595 c3c1bba27d46cace631b8ee96f02d73d 370 Gene3D G3DSA:3.40.50.720 200 354 0.035 T 28-03-2018 CU254_RS07595 c3c1bba27d46cace631b8ee96f02d73d 370 Pfam PF02625 XdhC and CoxI family 12 78 4.6E-20 T 28-03-2018 IPR003777 XdhC- CoxI CU254_RS07595 c3c1bba27d46cace631b8ee96f02d73d 370 Pfam PF02625 XdhC and CoxI family 117 180 2.9E-21 T 28-03-2018 IPR003777 XdhC- CoxI CU254_RS07595 c3c1bba27d46cace631b8ee96f02d73d 370 Pfam PF13478 XdhC Rossmann domain 203 349 2.2E-42 T 28-03-2018 IPR027051 XdhC Rossmann domain CU254_RS37555 00b87d42281e94a0d4499139a09690bb 261 PIRSF PIRSF037395 6 261 9.9E-88 T 28-03-2018 IPR017196 ECF transporter, predicted substrate-specific component UCP037395 CU254_RS37555 00b87d42281e94a0d4499139a09690bb 261 Pfam PF12822 ECF transporter, substrate-specific component 76 243 1.7E-17 T 28-03-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 CU254_RS36775 40b01034f00494ab5ef98ceb4990ae48 417 Gene3D G3DSA:1.20.1250.20 20 214 1.5E-14 T 28-03-2018 CU254_RS36775 40b01034f00494ab5ef98ceb4990ae48 417 Gene3D G3DSA:1.20.1250.20 215 406 1.8E-13 T 28-03-2018 CU254_RS36775 40b01034f00494ab5ef98ceb4990ae48 417 Pfam PF07690 Major Facilitator Superfamily 30 276 3.3E-14 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS36775 40b01034f00494ab5ef98ceb4990ae48 417 SUPERFAMILY SSF103473 30 399 1.57E-27 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS36775 40b01034f00494ab5ef98ceb4990ae48 417 PRINTS PR01035 Tetracycline resistance protein signature 378 398 2.9E-5 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CU254_RS36775 40b01034f00494ab5ef98ceb4990ae48 417 PRINTS PR01035 Tetracycline resistance protein signature 261 280 2.9E-5 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CU254_RS36775 40b01034f00494ab5ef98ceb4990ae48 417 PRINTS PR01035 Tetracycline resistance protein signature 350 372 2.9E-5 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CU254_RS36775 40b01034f00494ab5ef98ceb4990ae48 417 PRINTS PR01035 Tetracycline resistance protein signature 232 248 2.9E-5 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CU254_RS36775 40b01034f00494ab5ef98ceb4990ae48 417 PRINTS PR01035 Tetracycline resistance protein signature 292 316 2.9E-5 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CU254_RS34920 c61ccf541c3897bcfa26f32a23281044 186 Gene3D G3DSA:3.40.190.10 3 177 0.0013 T 28-03-2018 CU254_RS34920 c61ccf541c3897bcfa26f32a23281044 186 Pfam PF12079 Protein of unknown function (DUF3558) 14 145 4.7E-9 T 28-03-2018 IPR024520 Protein of unknown function DUF3558 CU254_RS04970 8b5555fc369dcb8f5b5edba9cea28c19 515 Pfam PF07730 Histidine kinase 181 245 1.3E-10 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CU254_RS04970 8b5555fc369dcb8f5b5edba9cea28c19 515 SUPERFAMILY SSF55874 263 372 5.16E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS04970 8b5555fc369dcb8f5b5edba9cea28c19 515 Gene3D G3DSA:3.30.565.10 246 379 1.8E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS10680 dfb3d8bc9e11a7bfb5ebc3fad178ac33 343 SUPERFAMILY SSF88946 45 180 6.02E-52 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS10680 dfb3d8bc9e11a7bfb5ebc3fad178ac33 343 Pfam PF04545 Sigma-70, region 4 278 331 1.8E-19 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS10680 dfb3d8bc9e11a7bfb5ebc3fad178ac33 343 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 303 329 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS10680 dfb3d8bc9e11a7bfb5ebc3fad178ac33 343 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 134 147 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS10680 dfb3d8bc9e11a7bfb5ebc3fad178ac33 343 Pfam PF04539 Sigma-70 region 3 189 264 7.8E-23 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS10680 dfb3d8bc9e11a7bfb5ebc3fad178ac33 343 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 107 331 3.0E-37 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS10680 dfb3d8bc9e11a7bfb5ebc3fad178ac33 343 Gene3D G3DSA:1.10.10.10 272 343 1.2E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS10680 dfb3d8bc9e11a7bfb5ebc3fad178ac33 343 SUPERFAMILY SSF88659 183 256 2.01E-17 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS10680 dfb3d8bc9e11a7bfb5ebc3fad178ac33 343 SUPERFAMILY SSF88659 240 338 1.08E-26 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS10680 dfb3d8bc9e11a7bfb5ebc3fad178ac33 343 Gene3D G3DSA:1.10.601.10 4 179 9.3E-68 T 28-03-2018 CU254_RS10680 dfb3d8bc9e11a7bfb5ebc3fad178ac33 343 PRINTS PR00046 Major sigma-70 factor signature 158 166 4.5E-28 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS10680 dfb3d8bc9e11a7bfb5ebc3fad178ac33 343 PRINTS PR00046 Major sigma-70 factor signature 134 147 4.5E-28 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS10680 dfb3d8bc9e11a7bfb5ebc3fad178ac33 343 PRINTS PR00046 Major sigma-70 factor signature 303 318 4.5E-28 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS10680 dfb3d8bc9e11a7bfb5ebc3fad178ac33 343 PRINTS PR00046 Major sigma-70 factor signature 282 294 4.5E-28 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS10680 dfb3d8bc9e11a7bfb5ebc3fad178ac33 343 PRINTS PR00046 Major sigma-70 factor signature 318 329 4.5E-28 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS10680 dfb3d8bc9e11a7bfb5ebc3fad178ac33 343 Pfam PF04542 Sigma-70 region 2 110 179 5.4E-22 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS10680 dfb3d8bc9e11a7bfb5ebc3fad178ac33 343 Pfam PF00140 Sigma-70 factor, region 1.2 45 78 1.5E-13 T 28-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS10680 dfb3d8bc9e11a7bfb5ebc3fad178ac33 343 Gene3D G3DSA:1.10.10.10 180 230 2.5E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS32735 70a639d6a6fe6cb2b668e20856b4d2c6 196 SUPERFAMILY SSF52499 10 194 5.1E-40 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CU254_RS32735 70a639d6a6fe6cb2b668e20856b4d2c6 196 Pfam PF00857 Isochorismatase family 23 192 2.9E-25 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CU254_RS32735 70a639d6a6fe6cb2b668e20856b4d2c6 196 Gene3D G3DSA:3.40.50.850 1 195 2.2E-33 T 28-03-2018 CU254_RS06530 1999b305e0d878a31cd08f502c67cdb8 184 Gene3D G3DSA:3.40.430.10 2 167 7.2E-26 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CU254_RS06530 1999b305e0d878a31cd08f502c67cdb8 184 SUPERFAMILY SSF53597 1 165 8.64E-18 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CU254_RS06530 1999b305e0d878a31cd08f502c67cdb8 184 Pfam PF01872 RibD C-terminal domain 3 164 1.4E-11 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CU254_RS26915 92bd89e0f990047dfccf8f202ce186df 559 SUPERFAMILY SSF53244 413 556 7.14E-27 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CU254_RS26915 92bd89e0f990047dfccf8f202ce186df 559 SUPERFAMILY SSF53623 115 405 8.65E-86 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CU254_RS26915 92bd89e0f990047dfccf8f202ce186df 559 Pfam PF08245 Mur ligase middle domain 156 385 3.7E-13 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CU254_RS26915 92bd89e0f990047dfccf8f202ce186df 559 Gene3D G3DSA:3.90.190.20 413 559 4.8E-29 T 28-03-2018 CU254_RS26915 92bd89e0f990047dfccf8f202ce186df 559 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 154 177 - T 28-03-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 CU254_RS26915 92bd89e0f990047dfccf8f202ce186df 559 Pfam PF02875 Mur ligase family, glutamate ligase domain 412 486 5.6E-10 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CU254_RS26915 92bd89e0f990047dfccf8f202ce186df 559 Gene3D G3DSA:3.40.1190.10 104 412 1.3E-81 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CU254_RS26915 92bd89e0f990047dfccf8f202ce186df 559 TIGRFAM TIGR01499 folC: bifunctional protein FolC 134 553 9.8E-102 T 28-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 CU254_RS05800 98bc4db92db9d759b259c223e98de98b 152 SUPERFAMILY SSF46785 7 141 6.83E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS05800 98bc4db92db9d759b259c223e98de98b 152 SMART SM00347 28 128 3.5E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS05800 98bc4db92db9d759b259c223e98de98b 152 Pfam PF01047 MarR family 47 92 4.8E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS05800 98bc4db92db9d759b259c223e98de98b 152 Gene3D G3DSA:1.10.10.10 1 149 6.9E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS22870 cd33226636f1ee6724bb702da999c8f7 189 SUPERFAMILY SSF46689 2 76 5.49E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS22870 cd33226636f1ee6724bb702da999c8f7 189 SUPERFAMILY SSF48498 75 183 7.23E-13 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS22870 cd33226636f1ee6724bb702da999c8f7 189 Gene3D G3DSA:1.10.10.60 1 37 2.6E-16 T 28-03-2018 CU254_RS22870 cd33226636f1ee6724bb702da999c8f7 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 55 8.2E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS22870 cd33226636f1ee6724bb702da999c8f7 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 3.9E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS22870 cd33226636f1ee6724bb702da999c8f7 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 3.9E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS22870 cd33226636f1ee6724bb702da999c8f7 189 Gene3D G3DSA:1.10.260.40 38 62 1.0E-4 T 28-03-2018 CU254_RS22870 cd33226636f1ee6724bb702da999c8f7 189 Gene3D G3DSA:1.10.357.10 63 184 1.7E-21 T 28-03-2018 CU254_RS34515 e1499af3e72cb88b69a74d0246963c61 238 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 119 141 - T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CU254_RS34515 e1499af3e72cb88b69a74d0246963c61 238 Pfam PF01066 CDP-alcohol phosphatidyltransferase 74 141 6.6E-8 T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CU254_RS16790 7ee7c18e1c8a8e3a0ad37752ce5370fd 218 Gene3D G3DSA:1.10.10.60 2 55 2.2E-19 T 28-03-2018 CU254_RS16790 7ee7c18e1c8a8e3a0ad37752ce5370fd 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 7.8E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS16790 7ee7c18e1c8a8e3a0ad37752ce5370fd 218 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 7.8E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS16790 7ee7c18e1c8a8e3a0ad37752ce5370fd 218 SUPERFAMILY SSF46689 9 85 2.36E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS16790 7ee7c18e1c8a8e3a0ad37752ce5370fd 218 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 66 5.6E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS16790 7ee7c18e1c8a8e3a0ad37752ce5370fd 218 SUPERFAMILY SSF48498 89 206 1.11E-5 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS16790 7ee7c18e1c8a8e3a0ad37752ce5370fd 218 Gene3D G3DSA:1.10.357.10 56 212 1.3E-20 T 28-03-2018 CU254_RS09565 a451001834a05b67d28f16563d440e51 646 TIGRFAM TIGR01196 edd: phosphogluconate dehydratase 14 611 6.6E-293 T 28-03-2018 IPR004786 6-phosphogluconate dehydratase GO:0004456|GO:0009255 KEGG: 00030+4.2.1.12 CU254_RS09565 a451001834a05b67d28f16563d440e51 646 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 164 174 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CU254_RS09565 a451001834a05b67d28f16563d440e51 646 SUPERFAMILY SSF143975 12 427 1.44E-146 T 28-03-2018 CU254_RS09565 a451001834a05b67d28f16563d440e51 646 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 514 525 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CU254_RS09565 a451001834a05b67d28f16563d440e51 646 Pfam PF00920 Dehydratase family 76 608 5.4E-165 T 28-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CU254_RS09565 a451001834a05b67d28f16563d440e51 646 SUPERFAMILY SSF52016 428 611 6.91E-56 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CU254_RS35800 8050e40965b9cc83d0fec884ec1262b8 242 Pfam PF12697 Alpha/beta hydrolase family 16 235 7.2E-24 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS35800 8050e40965b9cc83d0fec884ec1262b8 242 SUPERFAMILY SSF53474 7 237 4.53E-37 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS35800 8050e40965b9cc83d0fec884ec1262b8 242 Gene3D G3DSA:3.40.50.1820 6 239 4.1E-34 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS35800 8050e40965b9cc83d0fec884ec1262b8 242 PRINTS PR00111 Alpha/beta hydrolase fold signature 78 91 5.3E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS35800 8050e40965b9cc83d0fec884ec1262b8 242 PRINTS PR00111 Alpha/beta hydrolase fold signature 37 52 5.3E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS29760 448835db23cbeed3b9c085d4ab6545d1 210 Gene3D G3DSA:1.10.10.60 1 73 2.3E-18 T 28-03-2018 CU254_RS29760 448835db23cbeed3b9c085d4ab6545d1 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 66 1.4E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS29760 448835db23cbeed3b9c085d4ab6545d1 210 TIGRFAM TIGR03968 mycofact_TetR: mycofactocin system transcriptional regulator 12 199 1.1E-77 T 28-03-2018 IPR023851 Transcriptional regulator, TetR-type CU254_RS29760 448835db23cbeed3b9c085d4ab6545d1 210 Gene3D G3DSA:1.10.357.10 74 201 4.3E-22 T 28-03-2018 CU254_RS29760 448835db23cbeed3b9c085d4ab6545d1 210 SUPERFAMILY SSF46689 11 85 9.45E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS29760 448835db23cbeed3b9c085d4ab6545d1 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 1.9E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS29760 448835db23cbeed3b9c085d4ab6545d1 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 1.9E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS37745 e683e700daa89acd5b0bf0c439a45f0b 273 SUPERFAMILY SSF47413 11 60 9.65E-9 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS37745 e683e700daa89acd5b0bf0c439a45f0b 273 Gene3D G3DSA:1.10.260.40 1 84 1.0E-11 T 28-03-2018 CU254_RS37745 e683e700daa89acd5b0bf0c439a45f0b 273 Pfam PF13560 Helix-turn-helix domain 12 71 1.4E-11 T 28-03-2018 CU254_RS37745 e683e700daa89acd5b0bf0c439a45f0b 273 SMART SM00530 16 71 1.1E-5 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS00825 71a83d0d8a1fd9aaa90b23e305017f74 254 Gene3D G3DSA:3.60.40.10 11 253 0.0015 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CU254_RS00825 71a83d0d8a1fd9aaa90b23e305017f74 254 Pfam PF13672 Protein phosphatase 2C 33 215 5.5E-7 T 28-03-2018 CU254_RS08980 f47f365eaa2e3de1b279b6ed11901bb2 199 Pfam PF10821 Protein of unknown function (DUF2567) 49 195 1.3E-10 T 28-03-2018 IPR021213 Protein of unknown function DUF2567 CU254_RS34440 5677d2f8ddbd56216d4df38623bbb053 285 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 166 234 4.4E-11 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CU254_RS34440 5677d2f8ddbd56216d4df38623bbb053 285 Gene3D G3DSA:3.40.50.720 2 163 3.8E-40 T 28-03-2018 CU254_RS34440 5677d2f8ddbd56216d4df38623bbb053 285 SUPERFAMILY SSF51735 4 163 2.25E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS34440 5677d2f8ddbd56216d4df38623bbb053 285 Gene3D G3DSA:1.10.1040.10 166 285 2.0E-14 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CU254_RS34440 5677d2f8ddbd56216d4df38623bbb053 285 PIRSF PIRSF000105 1 249 1.3E-59 T 28-03-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 CU254_RS34440 5677d2f8ddbd56216d4df38623bbb053 285 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 51 161 1.5E-32 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CU254_RS34440 5677d2f8ddbd56216d4df38623bbb053 285 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 4 42 2.0E-6 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CU254_RS34440 5677d2f8ddbd56216d4df38623bbb053 285 SUPERFAMILY SSF48179 166 237 3.74E-9 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CU254_RS17895 34103fb48112720aa13152e167b9380e 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 1.6E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS17895 34103fb48112720aa13152e167b9380e 195 Gene3D G3DSA:1.10.357.10 2 190 1.7E-32 T 28-03-2018 CU254_RS17895 34103fb48112720aa13152e167b9380e 195 ProSitePatterns PS01081 TetR-type HTH domain signature. 28 58 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CU254_RS17895 34103fb48112720aa13152e167b9380e 195 SUPERFAMILY SSF48498 78 190 9.49E-11 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS17895 34103fb48112720aa13152e167b9380e 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 3.3E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS17895 34103fb48112720aa13152e167b9380e 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 3.3E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS17895 34103fb48112720aa13152e167b9380e 195 SUPERFAMILY SSF46689 1 74 1.9E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS38675 9c339efc837045e737284258acfd19b1 191 TIGRFAM TIGR01926 peroxid_rel: uncharacterized peroxidase-related enzyme 6 182 1.0E-56 T 28-03-2018 IPR010195 Uncharacterised peroxidase-related CU254_RS38675 9c339efc837045e737284258acfd19b1 191 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 63 110 2.3E-13 T 28-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CU254_RS38675 9c339efc837045e737284258acfd19b1 191 Pfam PF02627 Carboxymuconolactone decarboxylase family 45 126 1.4E-14 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CU254_RS38675 9c339efc837045e737284258acfd19b1 191 Gene3D G3DSA:1.20.1290.10 47 184 6.5E-27 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CU254_RS38675 9c339efc837045e737284258acfd19b1 191 Gene3D G3DSA:1.20.5.810 14 46 1.1E-20 T 28-03-2018 CU254_RS38675 9c339efc837045e737284258acfd19b1 191 SUPERFAMILY SSF69118 3 189 5.43E-54 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CU254_RS13680 29d8922561ad25eebf36556570708b88 407 Gene3D G3DSA:1.20.1250.20 14 213 5.4E-21 T 28-03-2018 CU254_RS13680 29d8922561ad25eebf36556570708b88 407 Gene3D G3DSA:1.20.1250.20 217 407 3.2E-14 T 28-03-2018 CU254_RS13680 29d8922561ad25eebf36556570708b88 407 Pfam PF07690 Major Facilitator Superfamily 28 241 2.8E-15 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS13680 29d8922561ad25eebf36556570708b88 407 SUPERFAMILY SSF103473 10 405 1.19E-38 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS20650 9d1dd471050bbf6d0062de415dbf0759 318 SUPERFAMILY SSF52518 7 317 1.53E-82 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS20650 9d1dd471050bbf6d0062de415dbf0759 318 Pfam PF00676 Dehydrogenase E1 component 13 309 2.6E-74 T 28-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 CU254_RS20650 9d1dd471050bbf6d0062de415dbf0759 318 Gene3D G3DSA:3.40.50.970 1 318 3.7E-73 T 28-03-2018 CU254_RS30060 fb4dd4038d1f799e26ed3464e3507db2 290 SUPERFAMILY SSF53756 1 288 2.95E-31 T 28-03-2018 CU254_RS30060 fb4dd4038d1f799e26ed3464e3507db2 290 Pfam PF06722 Protein of unknown function (DUF1205) 115 182 7.8E-7 T 28-03-2018 IPR010610 Domain of unknown function DUF1205 CU254_RS30060 fb4dd4038d1f799e26ed3464e3507db2 290 Gene3D G3DSA:3.40.50.2000 1 103 5.9E-7 T 28-03-2018 CU254_RS30060 fb4dd4038d1f799e26ed3464e3507db2 290 Gene3D G3DSA:3.40.50.2000 136 290 2.7E-10 T 28-03-2018 CU254_RS40120 0bd36ed71155a1aa704540efdad5fda5 301 Pfam PF01842 ACT domain 196 255 1.0E-7 T 28-03-2018 IPR002912 ACT domain CU254_RS40120 0bd36ed71155a1aa704540efdad5fda5 301 PIRSF PIRSF001500 1 271 2.5E-55 T 28-03-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CU254_RS40120 0bd36ed71155a1aa704540efdad5fda5 301 SUPERFAMILY SSF53850 3 183 3.01E-47 T 28-03-2018 CU254_RS40120 0bd36ed71155a1aa704540efdad5fda5 301 Gene3D G3DSA:3.30.70.260 180 275 5.5E-23 T 28-03-2018 CU254_RS40120 0bd36ed71155a1aa704540efdad5fda5 301 Pfam PF00800 Prephenate dehydratase 4 178 6.5E-46 T 28-03-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CU254_RS40120 0bd36ed71155a1aa704540efdad5fda5 301 ProSitePatterns PS00857 Prephenate dehydratase signature 1. 153 175 - T 28-03-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CU254_RS40120 0bd36ed71155a1aa704540efdad5fda5 301 SUPERFAMILY SSF55021 172 268 4.96E-17 T 28-03-2018 CU254_RS40120 0bd36ed71155a1aa704540efdad5fda5 301 Gene3D G3DSA:3.40.190.10 93 160 1.5E-20 T 28-03-2018 CU254_RS40120 0bd36ed71155a1aa704540efdad5fda5 301 Gene3D G3DSA:3.40.190.10 1 92 7.4E-27 T 28-03-2018 CU254_RS23350 fc787a178d77eea2946bdeee847a6182 391 Pfam PF04055 Radical SAM superfamily 50 185 1.6E-14 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CU254_RS23350 fc787a178d77eea2946bdeee847a6182 391 Pfam PF13186 Iron-sulfur cluster-binding domain 321 383 9.5E-8 T 28-03-2018 IPR023885 4Fe4S-binding SPASM domain CU254_RS23350 fc787a178d77eea2946bdeee847a6182 391 SUPERFAMILY SSF102114 42 247 1.23E-47 T 28-03-2018 CU254_RS23350 fc787a178d77eea2946bdeee847a6182 391 SUPERFAMILY SSF102114 277 387 1.23E-47 T 28-03-2018 CU254_RS23350 fc787a178d77eea2946bdeee847a6182 391 Gene3D G3DSA:3.20.20.70 38 371 5.2E-39 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS23350 fc787a178d77eea2946bdeee847a6182 391 Pfam PF13394 4Fe-4S single cluster domain 52 136 8.5E-7 T 28-03-2018 CU254_RS04700 5c7d6125b65a34e9efe9580790e38738 380 ProSitePatterns PS01081 TetR-type HTH domain signature. 30 60 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CU254_RS04700 5c7d6125b65a34e9efe9580790e38738 380 Gene3D G3DSA:1.10.357.10 250 379 6.1E-9 T 28-03-2018 CU254_RS04700 5c7d6125b65a34e9efe9580790e38738 380 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 9.8E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS04700 5c7d6125b65a34e9efe9580790e38738 380 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 9.8E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS04700 5c7d6125b65a34e9efe9580790e38738 380 Pfam PF00440 Bacterial regulatory proteins, tetR family 206 252 9.7E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS04700 5c7d6125b65a34e9efe9580790e38738 380 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 64 1.3E-17 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS04700 5c7d6125b65a34e9efe9580790e38738 380 SUPERFAMILY SSF46689 10 82 3.9E-19 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS04700 5c7d6125b65a34e9efe9580790e38738 380 Gene3D G3DSA:1.10.10.60 1 50 7.2E-20 T 28-03-2018 CU254_RS04700 5c7d6125b65a34e9efe9580790e38738 380 SUPERFAMILY SSF46689 196 267 2.77E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS04700 5c7d6125b65a34e9efe9580790e38738 380 Gene3D G3DSA:1.10.10.60 172 249 5.9E-18 T 28-03-2018 CU254_RS04700 5c7d6125b65a34e9efe9580790e38738 380 Gene3D G3DSA:1.10.10.60 51 137 3.7E-10 T 28-03-2018 CU254_RS28895 7abe702ae23f1e8680dbc40219f10f92 243 PRINTS PR00111 Alpha/beta hydrolase fold signature 71 84 7.2E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS28895 7abe702ae23f1e8680dbc40219f10f92 243 PRINTS PR00111 Alpha/beta hydrolase fold signature 29 44 7.2E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS28895 7abe702ae23f1e8680dbc40219f10f92 243 PRINTS PR00111 Alpha/beta hydrolase fold signature 85 98 7.2E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS28895 7abe702ae23f1e8680dbc40219f10f92 243 SUPERFAMILY SSF53474 5 239 1.94E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS28895 7abe702ae23f1e8680dbc40219f10f92 243 Gene3D G3DSA:3.40.50.1820 2 240 9.9E-24 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS28895 7abe702ae23f1e8680dbc40219f10f92 243 Pfam PF12697 Alpha/beta hydrolase family 6 235 7.2E-15 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS06880 c51206a3124025240a252d3e05a84b04 179 Gene3D G3DSA:2.60.120.10 35 179 2.6E-20 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS06880 c51206a3124025240a252d3e05a84b04 179 SUPERFAMILY SSF51182 109 175 1.17E-13 T 28-03-2018 IPR011051 RmlC-like cupin domain CU254_RS06880 c51206a3124025240a252d3e05a84b04 179 Pfam PF07883 Cupin domain 116 170 1.2E-9 T 28-03-2018 IPR013096 Cupin 2, conserved barrel CU254_RS36755 dee1ad7bec625704f455a5a042e35cd3 227 Gene3D G3DSA:1.10.1670.10 110 211 2.2E-31 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CU254_RS36755 dee1ad7bec625704f455a5a042e35cd3 227 PIRSF PIRSF001435 3 203 3.8E-45 T 28-03-2018 CU254_RS36755 dee1ad7bec625704f455a5a042e35cd3 227 SMART SM00478 30 177 2.1E-56 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CU254_RS36755 dee1ad7bec625704f455a5a042e35cd3 227 SMART SM00525 178 198 4.6E-6 T 28-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 CU254_RS36755 dee1ad7bec625704f455a5a042e35cd3 227 TIGRFAM TIGR01083 nth: endonuclease III 4 186 6.3E-79 T 28-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 CU254_RS36755 dee1ad7bec625704f455a5a042e35cd3 227 Gene3D G3DSA:1.10.340.30 13 109 8.9E-22 T 28-03-2018 CU254_RS36755 dee1ad7bec625704f455a5a042e35cd3 227 Hamap MF_00942 Endonuclease III [nth]. 1 201 36.525 T 28-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 CU254_RS36755 dee1ad7bec625704f455a5a042e35cd3 227 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 179 195 - T 28-03-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CU254_RS36755 dee1ad7bec625704f455a5a042e35cd3 227 ProSitePatterns PS01155 Endonuclease III family signature. 94 123 - T 28-03-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 CU254_RS36755 dee1ad7bec625704f455a5a042e35cd3 227 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 26 160 1.7E-18 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CU254_RS36755 dee1ad7bec625704f455a5a042e35cd3 227 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 179 195 4.0E-5 T 28-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 CU254_RS36755 dee1ad7bec625704f455a5a042e35cd3 227 Pfam PF00633 Helix-hairpin-helix motif 91 118 2.9E-8 T 28-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 CU254_RS36755 dee1ad7bec625704f455a5a042e35cd3 227 SUPERFAMILY SSF48150 5 198 9.42E-65 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CU254_RS26705 5af7dfcfbd804a3e0040174f6df10b34 86 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 14 86 1.0E-22 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS26705 5af7dfcfbd804a3e0040174f6df10b34 86 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 84 3.8E-22 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS26705 5af7dfcfbd804a3e0040174f6df10b34 86 SUPERFAMILY SSF46992 3 86 9.29E-28 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS26705 5af7dfcfbd804a3e0040174f6df10b34 86 Gene3D G3DSA:1.20.58.110 1 86 5.5E-28 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS26705 5af7dfcfbd804a3e0040174f6df10b34 86 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 16.684 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS26705 5af7dfcfbd804a3e0040174f6df10b34 86 Pfam PF01649 Ribosomal protein S20 2 84 4.6E-26 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS05885 8e054e7c11754305b9c2d4bc199c42fb 372 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 224 334 2.6E-15 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CU254_RS05885 8e054e7c11754305b9c2d4bc199c42fb 372 Gene3D G3DSA:3.40.50.970 3 176 1.0E-19 T 28-03-2018 CU254_RS05885 8e054e7c11754305b9c2d4bc199c42fb 372 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 236 255 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CU254_RS05885 8e054e7c11754305b9c2d4bc199c42fb 372 SUPERFAMILY SSF52518 22 158 2.85E-15 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS05885 8e054e7c11754305b9c2d4bc199c42fb 372 SUPERFAMILY SSF52518 177 359 3.16E-26 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS05885 8e054e7c11754305b9c2d4bc199c42fb 372 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 22 159 2.5E-11 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CU254_RS05885 8e054e7c11754305b9c2d4bc199c42fb 372 TIGRFAM TIGR03297 Ppyr-DeCO2ase: phosphonopyruvate decarboxylase 22 365 2.1E-96 T 28-03-2018 IPR017684 Phosphonopyruvate decarboxylase GO:0032923|GO:0033980 KEGG: 00440+4.1.1.82|MetaCyc: PWY-5757|MetaCyc: PWY-6322|MetaCyc: PWY-6682|MetaCyc: PWY-6839|MetaCyc: PWY-7510|MetaCyc: PWY-7769 CU254_RS05885 8e054e7c11754305b9c2d4bc199c42fb 372 Gene3D G3DSA:3.40.50.970 185 347 7.7E-20 T 28-03-2018 CU254_RS28865 469f3af0665cf96494e825d5fbd2d423 77 Gene3D G3DSA:1.10.600.10 10 77 8.3E-5 T 28-03-2018 IPR008949 Isoprenoid synthase domain CU254_RS12945 d919817a584857e4e0aa04216d94b737 1117 Gene3D G3DSA:3.30.559.10 79 273 1.1E-26 T 28-03-2018 CU254_RS12945 d919817a584857e4e0aa04216d94b737 1117 Pfam PF13193 AMP-binding enzyme C-terminal domain 927 993 7.0E-11 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS12945 d919817a584857e4e0aa04216d94b737 1117 Pfam PF00501 AMP-binding enzyme 547 646 8.6E-20 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS12945 d919817a584857e4e0aa04216d94b737 1117 Pfam PF00501 AMP-binding enzyme 654 919 6.1E-67 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS12945 d919817a584857e4e0aa04216d94b737 1117 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1042 1057 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CU254_RS12945 d919817a584857e4e0aa04216d94b737 1117 SUPERFAMILY SSF52777 93 257 2.45E-25 T 28-03-2018 CU254_RS12945 d919817a584857e4e0aa04216d94b737 1117 Gene3D G3DSA:3.40.50.980 671 827 4.6E-34 T 28-03-2018 CU254_RS12945 d919817a584857e4e0aa04216d94b737 1117 SUPERFAMILY SSF52777 267 511 9.89E-44 T 28-03-2018 CU254_RS12945 d919817a584857e4e0aa04216d94b737 1117 SUPERFAMILY SSF47336 1010 1084 1.03E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS12945 d919817a584857e4e0aa04216d94b737 1117 ProSitePatterns PS00455 Putative AMP-binding domain signature. 665 676 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS12945 d919817a584857e4e0aa04216d94b737 1117 Gene3D G3DSA:3.30.300.30 914 1021 2.9E-33 T 28-03-2018 CU254_RS12945 d919817a584857e4e0aa04216d94b737 1117 Gene3D G3DSA:1.10.1200.10 1022 1094 5.6E-21 T 28-03-2018 CU254_RS12945 d919817a584857e4e0aa04216d94b737 1117 Gene3D G3DSA:2.30.38.10 832 909 4.3E-26 T 28-03-2018 CU254_RS12945 d919817a584857e4e0aa04216d94b737 1117 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 569 941 2.1E-115 T 28-03-2018 IPR010071 Amino acid adenylation domain CU254_RS12945 d919817a584857e4e0aa04216d94b737 1117 Gene3D G3DSA:1.10.1200.10 2 78 2.7E-10 T 28-03-2018 CU254_RS12945 d919817a584857e4e0aa04216d94b737 1117 SMART SM00823 Phosphopantetheine attachment site 8 78 0.39 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS12945 d919817a584857e4e0aa04216d94b737 1117 SMART SM00823 Phosphopantetheine attachment site 1018 1088 0.0034 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS12945 d919817a584857e4e0aa04216d94b737 1117 Pfam PF00550 Phosphopantetheine attachment site 11 69 4.7E-6 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS12945 d919817a584857e4e0aa04216d94b737 1117 Pfam PF00550 Phosphopantetheine attachment site 1020 1084 7.7E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS12945 d919817a584857e4e0aa04216d94b737 1117 SUPERFAMILY SSF47336 10 109 4.84E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS12945 d919817a584857e4e0aa04216d94b737 1117 SUPERFAMILY SSF56801 540 1031 2.62E-137 T 28-03-2018 CU254_RS12945 d919817a584857e4e0aa04216d94b737 1117 Gene3D G3DSA:3.40.50.980 538 670 3.5E-32 T 28-03-2018 CU254_RS12945 d919817a584857e4e0aa04216d94b737 1117 Pfam PF00668 Condensation domain 97 505 8.8E-34 T 28-03-2018 IPR001242 Condensation domain CU254_RS39165 986c1550e84d1f5a7e7bc2a00b987e47 330 SUPERFAMILY SSF51905 7 306 2.42E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS39165 986c1550e84d1f5a7e7bc2a00b987e47 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 107 115 1.7E-76 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CU254_RS39165 986c1550e84d1f5a7e7bc2a00b987e47 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 1.7E-76 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CU254_RS39165 986c1550e84d1f5a7e7bc2a00b987e47 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 234 255 1.7E-76 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CU254_RS39165 986c1550e84d1f5a7e7bc2a00b987e47 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 269 287 1.7E-76 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CU254_RS39165 986c1550e84d1f5a7e7bc2a00b987e47 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 41 56 1.7E-76 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CU254_RS39165 986c1550e84d1f5a7e7bc2a00b987e47 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 129 141 1.7E-76 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CU254_RS39165 986c1550e84d1f5a7e7bc2a00b987e47 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 62 72 1.7E-76 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CU254_RS39165 986c1550e84d1f5a7e7bc2a00b987e47 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 144 168 1.7E-76 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CU254_RS39165 986c1550e84d1f5a7e7bc2a00b987e47 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 196 212 1.7E-76 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CU254_RS39165 986c1550e84d1f5a7e7bc2a00b987e47 330 Gene3D G3DSA:3.50.50.60 129 236 8.9E-23 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS39165 986c1550e84d1f5a7e7bc2a00b987e47 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 1.5E-35 T 28-03-2018 CU254_RS39165 986c1550e84d1f5a7e7bc2a00b987e47 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 232 248 1.5E-35 T 28-03-2018 CU254_RS39165 986c1550e84d1f5a7e7bc2a00b987e47 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 259 281 1.5E-35 T 28-03-2018 CU254_RS39165 986c1550e84d1f5a7e7bc2a00b987e47 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 1.5E-35 T 28-03-2018 CU254_RS39165 986c1550e84d1f5a7e7bc2a00b987e47 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 148 166 1.5E-35 T 28-03-2018 CU254_RS39165 986c1550e84d1f5a7e7bc2a00b987e47 330 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 8 306 3.1E-121 T 28-03-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 CU254_RS39165 986c1550e84d1f5a7e7bc2a00b987e47 330 Gene3D G3DSA:3.50.50.60 2 128 3.1E-23 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS39165 986c1550e84d1f5a7e7bc2a00b987e47 330 Gene3D G3DSA:3.50.50.60 237 321 4.0E-11 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS39165 986c1550e84d1f5a7e7bc2a00b987e47 330 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 295 2.4E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS13945 1588820b57d1bdce2cbe555f6900ff24 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 2.8E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS13945 1588820b57d1bdce2cbe555f6900ff24 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 2.8E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS13945 1588820b57d1bdce2cbe555f6900ff24 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 136 2.8E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS13945 1588820b57d1bdce2cbe555f6900ff24 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 2.8E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS13945 1588820b57d1bdce2cbe555f6900ff24 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 184 2.8E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS13945 1588820b57d1bdce2cbe555f6900ff24 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 133 161 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS13945 1588820b57d1bdce2cbe555f6900ff24 249 Gene3D G3DSA:3.40.50.720 1 173 5.6E-53 T 28-03-2018 CU254_RS13945 1588820b57d1bdce2cbe555f6900ff24 249 Gene3D G3DSA:3.40.50.720 174 221 4.5E-4 T 28-03-2018 CU254_RS13945 1588820b57d1bdce2cbe555f6900ff24 249 SUPERFAMILY SSF51735 3 241 1.1E-64 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS13945 1588820b57d1bdce2cbe555f6900ff24 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 73 84 1.7E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS13945 1588820b57d1bdce2cbe555f6900ff24 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 165 1.7E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS13945 1588820b57d1bdce2cbe555f6900ff24 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 126 134 1.7E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS13945 1588820b57d1bdce2cbe555f6900ff24 249 Pfam PF00106 short chain dehydrogenase 4 186 9.7E-54 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS13945 1588820b57d1bdce2cbe555f6900ff24 249 PIRSF PIRSF000126 1 246 3.9E-53 T 28-03-2018 CU254_RS13945 1588820b57d1bdce2cbe555f6900ff24 249 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 182 4.8E-5 T 28-03-2018 CU254_RS37495 8de6a29046cce6464d85fa244ab27cda 200 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 2 188 5.8E-59 T 28-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D CU254_RS37495 8de6a29046cce6464d85fa244ab27cda 200 SUPERFAMILY SSF50891 79 200 4.55E-39 T 28-03-2018 IPR029000 Cyclophilin-like domain CU254_RS37495 8de6a29046cce6464d85fa244ab27cda 200 Gene3D G3DSA:2.40.100.10 76 200 1.5E-48 T 28-03-2018 IPR029000 Cyclophilin-like domain CU254_RS37495 8de6a29046cce6464d85fa244ab27cda 200 Gene3D G3DSA:3.30.1360.40 1 74 2.4E-12 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CU254_RS37495 8de6a29046cce6464d85fa244ab27cda 200 SMART SM00796 1 189 2.0E-75 T 28-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D CU254_RS10970 2bf968e8b9ca7bc5c0e72a9bda134b1b 468 SUPERFAMILY SSF53720 2 466 8.51E-152 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CU254_RS10970 2bf968e8b9ca7bc5c0e72a9bda134b1b 468 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 247 254 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CU254_RS10970 2bf968e8b9ca7bc5c0e72a9bda134b1b 468 Gene3D G3DSA:3.40.309.10 266 449 8.5E-62 T 28-03-2018 CU254_RS10970 2bf968e8b9ca7bc5c0e72a9bda134b1b 468 Pfam PF00171 Aldehyde dehydrogenase family 19 463 1.0E-150 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CU254_RS10970 2bf968e8b9ca7bc5c0e72a9bda134b1b 468 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 275 286 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CU254_RS10970 2bf968e8b9ca7bc5c0e72a9bda134b1b 468 Gene3D G3DSA:3.40.605.10 1 265 5.0E-92 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CU254_RS23005 474629d99b4d89513073df20b227289e 240 SUPERFAMILY SSF52172 25 140 6.45E-8 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS23005 474629d99b4d89513073df20b227289e 240 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 199 8.7E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS23005 474629d99b4d89513073df20b227289e 240 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 199 211 8.7E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS23005 474629d99b4d89513073df20b227289e 240 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 183 8.7E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS23005 474629d99b4d89513073df20b227289e 240 SUPERFAMILY SSF46894 158 229 1.94E-18 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS23005 474629d99b4d89513073df20b227289e 240 Gene3D G3DSA:1.10.10.10 158 235 4.6E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS23005 474629d99b4d89513073df20b227289e 240 Gene3D G3DSA:3.40.50.2300 18 147 2.0E-8 T 28-03-2018 CU254_RS23005 474629d99b4d89513073df20b227289e 240 Pfam PF00072 Response regulator receiver domain 27 137 2.9E-5 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS23005 474629d99b4d89513073df20b227289e 240 SMART SM00421 166 223 2.7E-21 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS23005 474629d99b4d89513073df20b227289e 240 Pfam PF00196 Bacterial regulatory proteins, luxR family 168 221 1.0E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS28220 f7914d695fb64f2bb6f7ca83fdbd3d0d 572 SUPERFAMILY SSF52016 375 560 3.14E-58 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CU254_RS28220 f7914d695fb64f2bb6f7ca83fdbd3d0d 572 SUPERFAMILY SSF143975 3 374 5.23E-123 T 28-03-2018 CU254_RS28220 f7914d695fb64f2bb6f7ca83fdbd3d0d 572 Pfam PF00920 Dehydratase family 40 555 2.1E-175 T 28-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CU254_RS28220 f7914d695fb64f2bb6f7ca83fdbd3d0d 572 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 123 133 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CU254_RS15800 be08bd793a0812c31849db7c2fe9307d 149 Gene3D G3DSA:3.40.50.1820 36 149 0.001 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS27175 80d18a2447610d3325faf4a857e16c08 377 SUPERFAMILY SSF46785 8 71 2.73E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS27175 80d18a2447610d3325faf4a857e16c08 377 Gene3D G3DSA:3.30.420.40 78 201 1.1E-24 T 28-03-2018 CU254_RS27175 80d18a2447610d3325faf4a857e16c08 377 Pfam PF12802 MarR family 17 61 8.7E-7 T 28-03-2018 CU254_RS27175 80d18a2447610d3325faf4a857e16c08 377 Gene3D G3DSA:1.10.10.10 7 77 1.3E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS27175 80d18a2447610d3325faf4a857e16c08 377 Gene3D G3DSA:3.30.420.40 202 366 1.0E-38 T 28-03-2018 CU254_RS27175 80d18a2447610d3325faf4a857e16c08 377 Pfam PF00480 ROK family 84 360 8.6E-38 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CU254_RS27175 80d18a2447610d3325faf4a857e16c08 377 SUPERFAMILY SSF53067 81 361 2.31E-40 T 28-03-2018 CU254_RS09955 44833c965ea43c8333d9b206a4771dbd 400 Pfam PF02470 MlaD protein 44 120 2.1E-17 T 28-03-2018 IPR003399 Mce/MlaD CU254_RS09955 44833c965ea43c8333d9b206a4771dbd 400 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 173 287 8.6E-8 T 28-03-2018 IPR024516 Mammalian cell entry, C-terminal CU254_RS09955 44833c965ea43c8333d9b206a4771dbd 400 Gene3D G3DSA:1.20.1170.10 83 381 5.9E-7 T 28-03-2018 CU254_RS09955 44833c965ea43c8333d9b206a4771dbd 400 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 13 305 5.8E-67 T 28-03-2018 IPR005693 Virulence factor Mce protein CU254_RS08345 ee75e2e156f6938bf1ee1f6720a01bb7 130 Gene3D G3DSA:3.10.180.10 11 130 1.9E-21 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS08345 ee75e2e156f6938bf1ee1f6720a01bb7 130 SUPERFAMILY SSF54593 7 126 1.75E-22 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS08345 ee75e2e156f6938bf1ee1f6720a01bb7 130 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 12 123 7.9E-9 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CU254_RS34485 04f55464a92c144fc47a0288735496b0 466 Pfam PF00301 Rubredoxin 413 458 8.3E-18 T 28-03-2018 IPR024935 Rubredoxin domain GO:0005506 CU254_RS34485 04f55464a92c144fc47a0288735496b0 466 ProSitePatterns PS00202 Rubredoxin signature. 441 451 - T 28-03-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 CU254_RS34485 04f55464a92c144fc47a0288735496b0 466 SUPERFAMILY SSF57802 413 455 1.21E-14 T 28-03-2018 CU254_RS34485 04f55464a92c144fc47a0288735496b0 466 PRINTS PR00163 Rubredoxin signature 411 427 6.3E-5 T 28-03-2018 IPR024935 Rubredoxin domain GO:0005506 CU254_RS34485 04f55464a92c144fc47a0288735496b0 466 PRINTS PR00163 Rubredoxin signature 441 457 6.3E-5 T 28-03-2018 IPR024935 Rubredoxin domain GO:0005506 CU254_RS34485 04f55464a92c144fc47a0288735496b0 466 Gene3D G3DSA:2.20.28.10 411 460 5.5E-18 T 28-03-2018 CU254_RS34485 04f55464a92c144fc47a0288735496b0 466 PIRSF PIRSF036487 2 466 9.1E-295 T 28-03-2018 IPR014607 Alkane 1-monooxygenase, rubredoxin-type CU254_RS34485 04f55464a92c144fc47a0288735496b0 466 Pfam PF00487 Fatty acid desaturase 125 342 1.8E-31 T 28-03-2018 IPR005804 Fatty acid desaturase domain GO:0006629 CU254_RS27240 5345e8210ba9afeeef196d22839e1d86 106 SUPERFAMILY SSF48403 2 91 3.89E-8 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain CU254_RS27240 5345e8210ba9afeeef196d22839e1d86 106 Gene3D G3DSA:1.25.40.20 1 106 3.5E-12 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain CU254_RS18875 331f9b310aafca1848fe5d2185a0334e 232 Pfam PF12158 Protein of unknown function (DUF3592) 98 226 9.9E-9 T 28-03-2018 IPR021994 Protein of unknown function DUF3592 CU254_RS30675 975d59274d2976b31b76759f5b0c6bd2 167 Gene3D G3DSA:1.10.10.10 1 165 1.5E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS30675 975d59274d2976b31b76759f5b0c6bd2 167 SUPERFAMILY SSF46785 5 144 1.59E-43 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS30675 975d59274d2976b31b76759f5b0c6bd2 167 Pfam PF01638 HxlR-like helix-turn-helix 19 106 4.9E-22 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type CU254_RS23460 daf663f2faf3d2a5d1fca343a81b4767 276 SMART SM00346 9 96 3.2E-16 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS23460 daf663f2faf3d2a5d1fca343a81b4767 276 Pfam PF09339 IclR helix-turn-helix domain 12 59 6.3E-15 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS23460 daf663f2faf3d2a5d1fca343a81b4767 276 SUPERFAMILY SSF55781 71 240 5.3E-27 T 28-03-2018 IPR029016 GAF domain-like CU254_RS23460 daf663f2faf3d2a5d1fca343a81b4767 276 Gene3D G3DSA:3.30.450.40 75 246 3.7E-28 T 28-03-2018 IPR029016 GAF domain-like CU254_RS23460 daf663f2faf3d2a5d1fca343a81b4767 276 Pfam PF01614 Bacterial transcriptional regulator 129 237 2.5E-12 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal CU254_RS23460 daf663f2faf3d2a5d1fca343a81b4767 276 SUPERFAMILY SSF46785 12 79 8.89E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS23460 daf663f2faf3d2a5d1fca343a81b4767 276 Gene3D G3DSA:1.10.10.10 1 74 3.6E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS22370 7abd954a13f21c0f4dd4ab72be4dd1e7 590 PIRSF PIRSF003128 1 575 1.2E-156 T 28-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 CU254_RS22370 7abd954a13f21c0f4dd4ab72be4dd1e7 590 Pfam PF02463 RecF/RecN/SMC N terminal domain 11 525 2.1E-13 T 28-03-2018 IPR003395 RecF/RecN/SMC, N-terminal CU254_RS22370 7abd954a13f21c0f4dd4ab72be4dd1e7 590 SUPERFAMILY SSF52540 318 526 6.9E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS22370 7abd954a13f21c0f4dd4ab72be4dd1e7 590 SUPERFAMILY SSF52540 3 46 6.9E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS22370 7abd954a13f21c0f4dd4ab72be4dd1e7 590 SUPERFAMILY SSF52540 2 217 1.95E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS22370 7abd954a13f21c0f4dd4ab72be4dd1e7 590 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 570 3.8E-176 T 28-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 CU254_RS22370 7abd954a13f21c0f4dd4ab72be4dd1e7 590 Gene3D G3DSA:3.40.50.300 1 552 3.9E-36 T 28-03-2018 CU254_RS32360 b19398476b6267d5f1869bd165a7abc0 324 SUPERFAMILY SSF46785 6 54 2.82E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS32360 b19398476b6267d5f1869bd165a7abc0 324 SUPERFAMILY SSF54909 70 143 1.45E-6 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS32360 b19398476b6267d5f1869bd165a7abc0 324 Pfam PF13404 AsnC-type helix-turn-helix domain 7 47 7.1E-10 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS32360 b19398476b6267d5f1869bd165a7abc0 324 Gene3D G3DSA:1.10.10.10 174 227 2.6E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS32360 b19398476b6267d5f1869bd165a7abc0 324 Gene3D G3DSA:1.10.10.10 3 55 9.7E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS32360 b19398476b6267d5f1869bd165a7abc0 324 Gene3D G3DSA:3.30.70.920 230 321 1.9E-7 T 28-03-2018 CU254_RS32360 b19398476b6267d5f1869bd165a7abc0 324 Gene3D G3DSA:3.30.70.920 59 153 1.5E-9 T 28-03-2018 CU254_RS32360 b19398476b6267d5f1869bd165a7abc0 324 SMART SM00344 7 112 0.0012 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CU254_RS10785 1a18a452bf6ed722a4d11bb7e87955f3 203 Pfam PF13460 NAD(P)H-binding 8 193 3.1E-26 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS10785 1a18a452bf6ed722a4d11bb7e87955f3 203 Gene3D G3DSA:3.40.50.720 1 203 6.7E-19 T 28-03-2018 CU254_RS10785 1a18a452bf6ed722a4d11bb7e87955f3 203 SUPERFAMILY SSF51735 1 196 2.23E-31 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS34100 0cff759d05175ff608d80be46e3aa5b6 178 Pfam PF02575 YbaB/EbfC DNA-binding family 21 104 1.2E-9 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CU254_RS34100 0cff759d05175ff608d80be46e3aa5b6 178 Gene3D G3DSA:3.30.1310.10 16 115 5.2E-18 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CU254_RS34100 0cff759d05175ff608d80be46e3aa5b6 178 SUPERFAMILY SSF82607 17 105 2.35E-8 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CU254_RS30455 4a5933270e695e0c0c3a46cd9e4b99a8 271 Pfam PF08241 Methyltransferase domain 51 139 1.5E-21 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CU254_RS30455 4a5933270e695e0c0c3a46cd9e4b99a8 271 Gene3D G3DSA:3.40.50.150 37 267 3.1E-29 T 28-03-2018 CU254_RS30455 4a5933270e695e0c0c3a46cd9e4b99a8 271 SUPERFAMILY SSF53335 35 210 4.22E-32 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS37885 01ce4835b0abf7ea8bc4dfb697f17fda 536 SUPERFAMILY SSF140459 32 186 1.28E-5 T 28-03-2018 CU254_RS22000 e2b0531c5a78f2416affa9d77619cf83 758 Pfam PF00128 Alpha amylase, catalytic domain 26 232 4.5E-16 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CU254_RS22000 e2b0531c5a78f2416affa9d77619cf83 758 TIGRFAM TIGR02401 trehalose_TreY: malto-oligosyltrehalose synthase 4 755 9.1E-254 T 28-03-2018 IPR012767 Maltooligosyl trehalose synthase KEGG: 00500+5.4.99.15|MetaCyc: PWY-2661 CU254_RS22000 e2b0531c5a78f2416affa9d77619cf83 758 SUPERFAMILY SSF51445 4 674 3.97E-119 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS22000 e2b0531c5a78f2416affa9d77619cf83 758 Gene3D G3DSA:3.20.20.80 326 674 1.5E-44 T 28-03-2018 CU254_RS22000 e2b0531c5a78f2416affa9d77619cf83 758 Gene3D G3DSA:3.20.20.80 6 316 2.1E-61 T 28-03-2018 CU254_RS22000 e2b0531c5a78f2416affa9d77619cf83 758 SMART SM00642 11 640 1.1E-5 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CU254_RS34905 f52c0af7c0a104446d724828dd24dff5 265 Gene3D G3DSA:3.50.30.50 19 262 5.4E-52 T 28-03-2018 CU254_RS34905 f52c0af7c0a104446d724828dd24dff5 265 Pfam PF04199 Putative cyclase 24 199 1.2E-32 T 28-03-2018 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 CU254_RS34905 f52c0af7c0a104446d724828dd24dff5 265 SUPERFAMILY SSF102198 21 259 4.84E-50 T 28-03-2018 CU254_RS11520 6dd26db5d13ed1bafcf6bf2017402d9b 393 PIRSF PIRSF000497 1 391 1.2E-161 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CU254_RS11520 6dd26db5d13ed1bafcf6bf2017402d9b 393 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 1 391 54.259 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CU254_RS11520 6dd26db5d13ed1bafcf6bf2017402d9b 393 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 267 275 - T 28-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CU254_RS11520 6dd26db5d13ed1bafcf6bf2017402d9b 393 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 1 97 1.1E-39 T 28-03-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CU254_RS11520 6dd26db5d13ed1bafcf6bf2017402d9b 393 Gene3D G3DSA:3.30.300.10 152 266 1.5E-41 T 28-03-2018 CU254_RS11520 6dd26db5d13ed1bafcf6bf2017402d9b 393 Gene3D G3DSA:3.30.300.10 7 143 3.6E-44 T 28-03-2018 CU254_RS11520 6dd26db5d13ed1bafcf6bf2017402d9b 393 Pfam PF02772 S-adenosylmethionine synthetase, central domain 121 239 1.9E-43 T 28-03-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CU254_RS11520 6dd26db5d13ed1bafcf6bf2017402d9b 393 SUPERFAMILY SSF55973 1 105 6.47E-44 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CU254_RS11520 6dd26db5d13ed1bafcf6bf2017402d9b 393 Gene3D G3DSA:3.30.300.10 267 393 1.1E-44 T 28-03-2018 CU254_RS11520 6dd26db5d13ed1bafcf6bf2017402d9b 393 SUPERFAMILY SSF55973 116 240 2.24E-45 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CU254_RS11520 6dd26db5d13ed1bafcf6bf2017402d9b 393 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 1 390 1.2E-164 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CU254_RS11520 6dd26db5d13ed1bafcf6bf2017402d9b 393 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 122 132 - T 28-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CU254_RS11520 6dd26db5d13ed1bafcf6bf2017402d9b 393 SUPERFAMILY SSF55973 241 390 1.02E-65 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CU254_RS11520 6dd26db5d13ed1bafcf6bf2017402d9b 393 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 241 379 1.6E-65 T 28-03-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CU254_RS08930 c820d03d4d9f0bfb7e0d7dc797836f8e 465 Gene3D G3DSA:1.10.287.620 137 300 1.5E-5 T 28-03-2018 CU254_RS08930 c820d03d4d9f0bfb7e0d7dc797836f8e 465 Pfam PF05991 YacP-like NYN domain 345 462 1.1E-19 T 28-03-2018 IPR010298 Protein of unknown function DUF901 CU254_RS05965 4134700302404ac77fa2bf84d32dc538 247 Pfam PF00970 Oxidoreductase FAD-binding domain 16 108 6.5E-12 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CU254_RS05965 4134700302404ac77fa2bf84d32dc538 247 SUPERFAMILY SSF52343 99 240 6.16E-27 T 28-03-2018 CU254_RS05965 4134700302404ac77fa2bf84d32dc538 247 Gene3D G3DSA:2.40.30.10 5 98 1.1E-19 T 28-03-2018 CU254_RS05965 4134700302404ac77fa2bf84d32dc538 247 Gene3D G3DSA:3.40.50.80 99 239 5.0E-22 T 28-03-2018 CU254_RS05965 4134700302404ac77fa2bf84d32dc538 247 PRINTS PR00410 Phenol hydroxylase reductase family signature 120 139 1.7E-7 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CU254_RS05965 4134700302404ac77fa2bf84d32dc538 247 PRINTS PR00410 Phenol hydroxylase reductase family signature 40 52 1.7E-7 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CU254_RS05965 4134700302404ac77fa2bf84d32dc538 247 PRINTS PR00410 Phenol hydroxylase reductase family signature 210 218 1.7E-7 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CU254_RS05965 4134700302404ac77fa2bf84d32dc538 247 SUPERFAMILY SSF63380 10 110 4.66E-23 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CU254_RS05965 4134700302404ac77fa2bf84d32dc538 247 Pfam PF00175 Oxidoreductase NAD-binding domain 121 224 3.8E-10 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CU254_RS29065 ec64a075ba642dc8a1ba55615c5bb64b 319 Pfam PF12833 Helix-turn-helix domain 230 308 2.8E-23 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS29065 ec64a075ba642dc8a1ba55615c5bb64b 319 SUPERFAMILY SSF52317 1 190 4.89E-45 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS29065 ec64a075ba642dc8a1ba55615c5bb64b 319 SUPERFAMILY SSF46689 260 310 1.02E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS29065 ec64a075ba642dc8a1ba55615c5bb64b 319 SMART SM00342 224 307 3.2E-29 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS29065 ec64a075ba642dc8a1ba55615c5bb64b 319 SUPERFAMILY SSF46689 210 257 3.27E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS29065 ec64a075ba642dc8a1ba55615c5bb64b 319 Pfam PF01965 DJ-1/PfpI family 18 169 5.4E-17 T 28-03-2018 IPR002818 DJ-1/PfpI CU254_RS29065 ec64a075ba642dc8a1ba55615c5bb64b 319 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 261 303 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CU254_RS29065 ec64a075ba642dc8a1ba55615c5bb64b 319 Gene3D G3DSA:3.40.50.880 2 226 3.0E-55 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS29065 ec64a075ba642dc8a1ba55615c5bb64b 319 Gene3D G3DSA:1.10.10.60 227 266 7.2E-14 T 28-03-2018 CU254_RS29065 ec64a075ba642dc8a1ba55615c5bb64b 319 Gene3D G3DSA:1.10.10.60 267 316 1.8E-11 T 28-03-2018 CU254_RS21060 5f8c1d60bcc3e0dc5f683c8f55b05616 486 Gene3D G3DSA:3.40.605.10 9 269 2.8E-76 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CU254_RS21060 5f8c1d60bcc3e0dc5f683c8f55b05616 486 Pfam PF00171 Aldehyde dehydrogenase family 17 475 5.3E-141 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CU254_RS21060 5f8c1d60bcc3e0dc5f683c8f55b05616 486 Gene3D G3DSA:3.40.309.10 270 458 2.5E-58 T 28-03-2018 CU254_RS21060 5f8c1d60bcc3e0dc5f683c8f55b05616 486 SUPERFAMILY SSF53720 10 478 5.89E-137 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CU254_RS21060 5f8c1d60bcc3e0dc5f683c8f55b05616 486 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 251 258 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CU254_RS21060 5f8c1d60bcc3e0dc5f683c8f55b05616 486 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 279 290 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CU254_RS25000 ca705b286af9fd8edcc6469723a145f5 479 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 56 214 5.6E-12 T 28-03-2018 CU254_RS27290 a537006464428052c7ceec7974dc1388 144 Pfam PF05962 HutD 6 123 1.4E-30 T 28-03-2018 IPR010282 Uncharacterised protein family HutD/Ves CU254_RS27290 a537006464428052c7ceec7974dc1388 144 Gene3D G3DSA:2.60.120.10 101 141 0.012 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS27290 a537006464428052c7ceec7974dc1388 144 Gene3D G3DSA:2.60.120.10 4 100 3.9E-27 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS27290 a537006464428052c7ceec7974dc1388 144 SUPERFAMILY SSF51182 5 119 2.82E-29 T 28-03-2018 IPR011051 RmlC-like cupin domain CU254_RS00960 45578b01aa6670a4be33212f376f6566 205 Gene3D G3DSA:1.10.10.60 3 47 1.1E-13 T 28-03-2018 CU254_RS00960 45578b01aa6670a4be33212f376f6566 205 Gene3D G3DSA:1.10.10.60 48 195 1.4E-5 T 28-03-2018 CU254_RS00960 45578b01aa6670a4be33212f376f6566 205 SUPERFAMILY SSF46689 3 75 3.04E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS00960 45578b01aa6670a4be33212f376f6566 205 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 60 3.5E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS35545 3de8137e587c6c71daff815c69d8cfef 142 Pfam PF12802 MarR family 32 88 1.1E-11 T 28-03-2018 CU254_RS35545 3de8137e587c6c71daff815c69d8cfef 142 Gene3D G3DSA:1.10.10.10 1 120 2.3E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS35545 3de8137e587c6c71daff815c69d8cfef 142 SMART SM00347 24 124 5.4E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS35545 3de8137e587c6c71daff815c69d8cfef 142 SUPERFAMILY SSF46785 9 136 7.37E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS06990 a3b8b3bd625dd3137e5085681872d720 166 SUPERFAMILY SSF46785 13 151 4.47E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS06990 a3b8b3bd625dd3137e5085681872d720 166 Pfam PF01047 MarR family 45 103 3.9E-16 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS06990 a3b8b3bd625dd3137e5085681872d720 166 SMART SM00347 38 138 4.1E-20 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS06990 a3b8b3bd625dd3137e5085681872d720 166 Gene3D G3DSA:1.10.10.10 4 153 6.6E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS06990 a3b8b3bd625dd3137e5085681872d720 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 79 94 3.8E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS06990 a3b8b3bd625dd3137e5085681872d720 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 98 114 3.8E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS06990 a3b8b3bd625dd3137e5085681872d720 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 62 78 3.8E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS04665 47cffcf0268edd1dec5298c474911c95 281 SUPERFAMILY SSF69118 24 157 2.44E-14 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CU254_RS04665 47cffcf0268edd1dec5298c474911c95 281 Gene3D G3DSA:1.20.1290.10 11 276 3.4E-16 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CU254_RS05440 223489a546bd14f217541701860a6711 243 SUPERFAMILY SSF53850 21 195 6.29E-24 T 28-03-2018 CU254_RS05440 223489a546bd14f217541701860a6711 243 Gene3D G3DSA:3.40.190.10 6 88 3.2E-16 T 28-03-2018 CU254_RS05440 223489a546bd14f217541701860a6711 243 Gene3D G3DSA:3.40.190.10 89 168 9.1E-11 T 28-03-2018 CU254_RS05440 223489a546bd14f217541701860a6711 243 Pfam PF03466 LysR substrate binding domain 22 193 3.2E-23 T 28-03-2018 IPR005119 LysR, substrate-binding CU254_RS23920 e1c95449700b11c1a32ecf6cbc41fcad 392 Gene3D G3DSA:1.10.540.10 1 128 4.1E-29 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS23920 e1c95449700b11c1a32ecf6cbc41fcad 392 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 130 222 1.5E-22 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CU254_RS23920 e1c95449700b11c1a32ecf6cbc41fcad 392 Gene3D G3DSA:1.20.140.10 234 392 9.4E-40 T 28-03-2018 CU254_RS23920 e1c95449700b11c1a32ecf6cbc41fcad 392 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 236 384 6.7E-28 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS23920 e1c95449700b11c1a32ecf6cbc41fcad 392 SUPERFAMILY SSF47203 236 386 5.68E-22 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS23920 e1c95449700b11c1a32ecf6cbc41fcad 392 Gene3D G3DSA:2.40.110.10 129 233 1.1E-30 T 28-03-2018 CU254_RS23920 e1c95449700b11c1a32ecf6cbc41fcad 392 SUPERFAMILY SSF56645 2 247 2.49E-66 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS23920 e1c95449700b11c1a32ecf6cbc41fcad 392 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 123 2.2E-22 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS35495 16ad53fbaf8c6ac17edb05d49be679a3 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 5.6E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS35495 16ad53fbaf8c6ac17edb05d49be679a3 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 5.6E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS35495 16ad53fbaf8c6ac17edb05d49be679a3 200 SUPERFAMILY SSF48498 76 182 6.67E-19 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS35495 16ad53fbaf8c6ac17edb05d49be679a3 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 57 2.3E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS35495 16ad53fbaf8c6ac17edb05d49be679a3 200 ProSitePatterns PS01081 TetR-type HTH domain signature. 24 54 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CU254_RS35495 16ad53fbaf8c6ac17edb05d49be679a3 200 Gene3D G3DSA:1.10.357.10 1 187 3.2E-32 T 28-03-2018 CU254_RS35495 16ad53fbaf8c6ac17edb05d49be679a3 200 SUPERFAMILY SSF46689 3 80 6.98E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS07530 ec66e467e2d6cf5eeab8528be35ed828 375 PIRSF PIRSF006078 2 375 1.7E-120 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CU254_RS07530 ec66e467e2d6cf5eeab8528be35ed828 375 Gene3D G3DSA:3.90.1510.10 43 274 4.5E-78 T 28-03-2018 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 CU254_RS07530 ec66e467e2d6cf5eeab8528be35ed828 375 Pfam PF02595 Glycerate kinase family 4 368 3.7E-121 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CU254_RS07530 ec66e467e2d6cf5eeab8528be35ed828 375 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 3 364 6.1E-115 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CU254_RS07530 ec66e467e2d6cf5eeab8528be35ed828 375 SUPERFAMILY SSF110738 3 367 1.31E-110 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CU254_RS33520 f440b0fcbc2b99f6860b7b916f6fd34b 332 Gene3D G3DSA:3.40.50.300 2 331 7.3E-86 T 28-03-2018 CU254_RS33520 f440b0fcbc2b99f6860b7b916f6fd34b 332 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 237 304 5.1E-17 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CU254_RS33520 f440b0fcbc2b99f6860b7b916f6fd34b 332 SMART SM00382 42 243 4.3E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS33520 f440b0fcbc2b99f6860b7b916f6fd34b 332 Pfam PF00005 ABC transporter 34 185 1.2E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS33520 f440b0fcbc2b99f6860b7b916f6fd34b 332 SUPERFAMILY SSF52540 6 257 2.5E-75 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS33520 f440b0fcbc2b99f6860b7b916f6fd34b 332 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS33520 f440b0fcbc2b99f6860b7b916f6fd34b 332 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 235 324 1.1E-28 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CU254_RS07125 b7b97a60aa96b8869995041d8b352eae 319 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 11 314 29.86 T 28-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 CU254_RS07125 b7b97a60aa96b8869995041d8b352eae 319 Gene3D G3DSA:3.30.1330.10 6 150 3.7E-34 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CU254_RS07125 b7b97a60aa96b8869995041d8b352eae 319 PIRSF PIRSF005303 6 317 1.4E-90 T 28-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 CU254_RS07125 b7b97a60aa96b8869995041d8b352eae 319 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 12 316 4.0E-86 T 28-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 CU254_RS07125 b7b97a60aa96b8869995041d8b352eae 319 SUPERFAMILY SSF56042 151 306 1.21E-30 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CU254_RS07125 b7b97a60aa96b8869995041d8b352eae 319 Pfam PF02769 AIR synthase related protein, C-terminal domain 159 247 5.3E-6 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CU254_RS07125 b7b97a60aa96b8869995041d8b352eae 319 SUPERFAMILY SSF55326 12 146 4.97E-34 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CU254_RS07125 b7b97a60aa96b8869995041d8b352eae 319 Gene3D G3DSA:3.90.650.10 154 317 1.4E-41 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CU254_RS07125 b7b97a60aa96b8869995041d8b352eae 319 Pfam PF00586 AIR synthase related protein, N-terminal domain 36 145 6.6E-21 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CU254_RS03155 19b8170ef028255296607032ae8bd6fd 467 Gene3D G3DSA:3.50.50.60 1 159 1.9E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS03155 19b8170ef028255296607032ae8bd6fd 467 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 349 456 2.1E-23 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CU254_RS03155 19b8170ef028255296607032ae8bd6fd 467 PIRSF PIRSF000350 1 457 6.2E-77 T 28-03-2018 CU254_RS03155 19b8170ef028255296607032ae8bd6fd 467 SUPERFAMILY SSF55424 347 463 8.08E-27 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CU254_RS03155 19b8170ef028255296607032ae8bd6fd 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 180 198 5.8E-35 T 28-03-2018 CU254_RS03155 19b8170ef028255296607032ae8bd6fd 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 141 159 5.8E-35 T 28-03-2018 CU254_RS03155 19b8170ef028255296607032ae8bd6fd 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 5.8E-35 T 28-03-2018 CU254_RS03155 19b8170ef028255296607032ae8bd6fd 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 264 280 5.8E-35 T 28-03-2018 CU254_RS03155 19b8170ef028255296607032ae8bd6fd 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 293 315 5.8E-35 T 28-03-2018 CU254_RS03155 19b8170ef028255296607032ae8bd6fd 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 431 451 2.9E-50 T 28-03-2018 CU254_RS03155 19b8170ef028255296607032ae8bd6fd 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 409 424 2.9E-50 T 28-03-2018 CU254_RS03155 19b8170ef028255296607032ae8bd6fd 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 308 315 2.9E-50 T 28-03-2018 CU254_RS03155 19b8170ef028255296607032ae8bd6fd 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 35 50 2.9E-50 T 28-03-2018 CU254_RS03155 19b8170ef028255296607032ae8bd6fd 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 180 205 2.9E-50 T 28-03-2018 CU254_RS03155 19b8170ef028255296607032ae8bd6fd 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 344 365 2.9E-50 T 28-03-2018 CU254_RS03155 19b8170ef028255296607032ae8bd6fd 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 144 153 2.9E-50 T 28-03-2018 CU254_RS03155 19b8170ef028255296607032ae8bd6fd 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 2.9E-50 T 28-03-2018 CU254_RS03155 19b8170ef028255296607032ae8bd6fd 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 265 279 2.9E-50 T 28-03-2018 CU254_RS03155 19b8170ef028255296607032ae8bd6fd 467 Gene3D G3DSA:3.50.50.60 160 277 3.0E-23 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS03155 19b8170ef028255296607032ae8bd6fd 467 Gene3D G3DSA:3.30.390.30 348 462 2.5E-27 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CU254_RS03155 19b8170ef028255296607032ae8bd6fd 467 SUPERFAMILY SSF51905 137 337 9.91E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS03155 19b8170ef028255296607032ae8bd6fd 467 SUPERFAMILY SSF51905 3 102 9.91E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS03155 19b8170ef028255296607032ae8bd6fd 467 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 328 7.8E-62 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS03155 19b8170ef028255296607032ae8bd6fd 467 Gene3D G3DSA:3.50.50.60 278 347 1.1E-13 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS24585 f884f2ad6284f51c6878dbde70f2c692 374 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 18 367 1.2E-82 T 28-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CU254_RS24585 f884f2ad6284f51c6878dbde70f2c692 374 Gene3D G3DSA:3.40.50.2000 12 180 7.5E-31 T 28-03-2018 CU254_RS24585 f884f2ad6284f51c6878dbde70f2c692 374 SUPERFAMILY SSF53756 19 372 1.11E-96 T 28-03-2018 CU254_RS24585 f884f2ad6284f51c6878dbde70f2c692 374 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 203 362 4.5E-34 T 28-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CU254_RS24585 f884f2ad6284f51c6878dbde70f2c692 374 Gene3D G3DSA:3.40.50.2000 181 366 1.2E-35 T 28-03-2018 CU254_RS24585 f884f2ad6284f51c6878dbde70f2c692 374 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 19 372 30.661 T 28-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CU254_RS24585 f884f2ad6284f51c6878dbde70f2c692 374 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 19 157 1.1E-36 T 28-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CU254_RS30165 07b24caf6453233160a049aa1199749c 404 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 38 272 6.7E-36 T 28-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 CU254_RS30165 07b24caf6453233160a049aa1199749c 404 PRINTS PR01182 Ornithine decarboxylase signature 348 361 6.3E-8 T 28-03-2018 IPR002433 Ornithine decarboxylase GO:0006596 CU254_RS30165 07b24caf6453233160a049aa1199749c 404 PRINTS PR01182 Ornithine decarboxylase signature 40 67 6.3E-8 T 28-03-2018 IPR002433 Ornithine decarboxylase GO:0006596 CU254_RS30165 07b24caf6453233160a049aa1199749c 404 PRINTS PR01182 Ornithine decarboxylase signature 84 108 6.3E-8 T 28-03-2018 IPR002433 Ornithine decarboxylase GO:0006596 CU254_RS30165 07b24caf6453233160a049aa1199749c 404 PRINTS PR01182 Ornithine decarboxylase signature 328 338 6.3E-8 T 28-03-2018 IPR002433 Ornithine decarboxylase GO:0006596 CU254_RS30165 07b24caf6453233160a049aa1199749c 404 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 42 60 - T 28-03-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site CU254_RS30165 07b24caf6453233160a049aa1199749c 404 SUPERFAMILY SSF51419 12 275 2.45E-57 T 28-03-2018 IPR029066 PLP-binding barrel CU254_RS30165 07b24caf6453233160a049aa1199749c 404 Gene3D G3DSA:2.40.37.10 264 394 2.5E-28 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CU254_RS30165 07b24caf6453233160a049aa1199749c 404 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 213 226 - T 28-03-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site CU254_RS30165 07b24caf6453233160a049aa1199749c 404 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 16 361 9.2E-14 T 28-03-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 CU254_RS30165 07b24caf6453233160a049aa1199749c 404 Gene3D G3DSA:3.20.20.10 27 263 7.4E-50 T 28-03-2018 IPR029066 PLP-binding barrel CU254_RS30165 07b24caf6453233160a049aa1199749c 404 SUPERFAMILY SSF50621 248 388 2.72E-31 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CU254_RS11050 fb9f06bf7bca4fb830db45123f855d2e 254 SUPERFAMILY SSF46785 8 76 1.25E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS11050 fb9f06bf7bca4fb830db45123f855d2e 254 SMART SM00346 5 94 1.5E-27 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS11050 fb9f06bf7bca4fb830db45123f855d2e 254 Pfam PF09339 IclR helix-turn-helix domain 7 58 4.8E-15 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS11050 fb9f06bf7bca4fb830db45123f855d2e 254 SUPERFAMILY SSF55781 69 247 9.81E-42 T 28-03-2018 IPR029016 GAF domain-like CU254_RS11050 fb9f06bf7bca4fb830db45123f855d2e 254 Gene3D G3DSA:3.30.450.40 75 254 2.0E-44 T 28-03-2018 IPR029016 GAF domain-like CU254_RS11050 fb9f06bf7bca4fb830db45123f855d2e 254 Gene3D G3DSA:1.10.10.10 1 74 2.4E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS11050 fb9f06bf7bca4fb830db45123f855d2e 254 Pfam PF01614 Bacterial transcriptional regulator 124 236 2.8E-23 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal CU254_RS08745 d3a23b70aa5148ff9402099e7fb980b5 292 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 209 1.4E-12 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CU254_RS08745 d3a23b70aa5148ff9402099e7fb980b5 292 SUPERFAMILY SSF51735 1 287 5.47E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS08745 d3a23b70aa5148ff9402099e7fb980b5 292 Gene3D G3DSA:3.40.50.720 1 292 1.2E-32 T 28-03-2018 CU254_RS08745 d3a23b70aa5148ff9402099e7fb980b5 292 Pfam PF08338 Domain of unknown function (DUF1731) 244 290 1.8E-16 T 28-03-2018 IPR013549 Domain of unknown function DUF1731 CU254_RS08745 d3a23b70aa5148ff9402099e7fb980b5 292 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 3 288 6.4E-93 T 28-03-2018 IPR010099 Epimerase family protein SDR39U1 CU254_RS18590 24ad06afbe605cbd5700f5b2497a86b9 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.6E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18590 24ad06afbe605cbd5700f5b2497a86b9 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 1.6E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18590 24ad06afbe605cbd5700f5b2497a86b9 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 1.6E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18590 24ad06afbe605cbd5700f5b2497a86b9 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 2.9E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18590 24ad06afbe605cbd5700f5b2497a86b9 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 2.9E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18590 24ad06afbe605cbd5700f5b2497a86b9 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 2.9E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18590 24ad06afbe605cbd5700f5b2497a86b9 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 2.9E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18590 24ad06afbe605cbd5700f5b2497a86b9 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 2.9E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18590 24ad06afbe605cbd5700f5b2497a86b9 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 2.9E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18590 24ad06afbe605cbd5700f5b2497a86b9 253 Gene3D G3DSA:3.40.50.720 51 253 7.0E-62 T 28-03-2018 CU254_RS18590 24ad06afbe605cbd5700f5b2497a86b9 253 Gene3D G3DSA:3.40.50.720 1 50 6.7E-11 T 28-03-2018 CU254_RS18590 24ad06afbe605cbd5700f5b2497a86b9 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS18590 24ad06afbe605cbd5700f5b2497a86b9 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 250 1.5E-62 T 28-03-2018 CU254_RS18590 24ad06afbe605cbd5700f5b2497a86b9 253 SUPERFAMILY SSF51735 8 251 8.89E-80 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS33815 f4df60658dfd5199fa6281fd0167fb96 589 Pfam PF00005 ABC transporter 300 434 8.6E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS33815 f4df60658dfd5199fa6281fd0167fb96 589 Pfam PF00005 ABC transporter 20 153 9.3E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS33815 f4df60658dfd5199fa6281fd0167fb96 589 ProSitePatterns PS00211 ABC transporters family signature. 406 420 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS33815 f4df60658dfd5199fa6281fd0167fb96 589 SUPERFAMILY SSF52540 4 204 1.14E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS33815 f4df60658dfd5199fa6281fd0167fb96 589 Gene3D G3DSA:3.40.50.300 281 584 6.1E-51 T 28-03-2018 CU254_RS33815 f4df60658dfd5199fa6281fd0167fb96 589 SMART SM00382 309 478 3.8E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS33815 f4df60658dfd5199fa6281fd0167fb96 589 SMART SM00382 29 205 1.1E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS33815 f4df60658dfd5199fa6281fd0167fb96 589 Pfam PF12848 ABC transporter 192 265 2.8E-7 T 28-03-2018 IPR032781 ABC-transporter extension domain CU254_RS33815 f4df60658dfd5199fa6281fd0167fb96 589 ProSitePatterns PS00211 ABC transporters family signature. 125 139 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS33815 f4df60658dfd5199fa6281fd0167fb96 589 Gene3D G3DSA:3.40.50.300 1 263 9.1E-52 T 28-03-2018 CU254_RS33815 f4df60658dfd5199fa6281fd0167fb96 589 SUPERFAMILY SSF52540 272 483 1.07E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS41410 6c81234d3edfa9b4e78c48bdf6be713c 251 Pfam PF13471 Transglutaminase-like superfamily 135 239 4.4E-18 T 28-03-2018 IPR032708 Microcin J25-processing protein McjB, C-terminal CU254_RS08830 e24b30df037058cfa3d49c1c80c2eac2 219 Pfam PF11241 Protein of unknown function (DUF3043) 35 215 5.3E-61 T 28-03-2018 IPR021403 Protein of unknown function DUF3043 CU254_RS29880 a2e1a8dd62be5e298d57ed521a155ea3 308 SUPERFAMILY SSF143631 5 300 8.89E-59 T 28-03-2018 IPR003374 ApbE-like domain CU254_RS29880 a2e1a8dd62be5e298d57ed521a155ea3 308 Pfam PF02424 ApbE family 13 280 5.8E-50 T 28-03-2018 IPR024932 Flavin transferase ApbE GO:0017013 CU254_RS29880 a2e1a8dd62be5e298d57ed521a155ea3 308 Gene3D G3DSA:3.10.520.10 8 300 4.0E-33 T 28-03-2018 CU254_RS18005 6c2a09d9f6025b5d7fae835b4900726b 354 SUPERFAMILY SSF52540 23 306 1.4E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS18005 6c2a09d9f6025b5d7fae835b4900726b 354 PIRSF PIRSF002849 5 336 4.8E-134 T 28-03-2018 CU254_RS18005 6c2a09d9f6025b5d7fae835b4900726b 354 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 55 185 1.7E-59 T 28-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 CU254_RS18005 6c2a09d9f6025b5d7fae835b4900726b 354 Gene3D G3DSA:3.40.50.300 36 202 2.0E-25 T 28-03-2018 CU254_RS18005 6c2a09d9f6025b5d7fae835b4900726b 354 Gene3D G3DSA:1.10.8.300 214 331 2.5E-31 T 28-03-2018 CU254_RS09895 b7cf011e3bb5d7eeb08fb98797a9f845 987 Gene3D G3DSA:3.30.470.20 845 969 4.4E-32 T 28-03-2018 CU254_RS09895 b7cf011e3bb5d7eeb08fb98797a9f845 987 Pfam PF13380 CoA binding domain 300 424 7.2E-23 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CU254_RS09895 b7cf011e3bb5d7eeb08fb98797a9f845 987 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 443 576 2.3E-44 T 28-03-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain CU254_RS09895 b7cf011e3bb5d7eeb08fb98797a9f845 987 Gene3D G3DSA:3.40.50.261 416 574 1.1E-42 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CU254_RS09895 b7cf011e3bb5d7eeb08fb98797a9f845 987 Gene3D G3DSA:3.40.630.30 110 293 4.7E-31 T 28-03-2018 CU254_RS09895 b7cf011e3bb5d7eeb08fb98797a9f845 987 SUPERFAMILY SSF52210 583 728 9.29E-24 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CU254_RS09895 b7cf011e3bb5d7eeb08fb98797a9f845 987 SMART SM00881 295 390 2.6E-35 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CU254_RS09895 b7cf011e3bb5d7eeb08fb98797a9f845 987 SUPERFAMILY SSF52210 421 580 1.1E-36 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CU254_RS09895 b7cf011e3bb5d7eeb08fb98797a9f845 987 SUPERFAMILY SSF51735 290 426 3.24E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS09895 b7cf011e3bb5d7eeb08fb98797a9f845 987 Pfam PF00583 Acetyltransferase (GNAT) family 155 253 1.2E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS09895 b7cf011e3bb5d7eeb08fb98797a9f845 987 Gene3D G3DSA:3.40.50.261 575 721 8.5E-29 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CU254_RS09895 b7cf011e3bb5d7eeb08fb98797a9f845 987 SUPERFAMILY SSF55729 117 258 1.37E-25 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS09895 b7cf011e3bb5d7eeb08fb98797a9f845 987 Pfam PF13549 ATP-grasp domain 759 966 5.0E-54 T 28-03-2018 CU254_RS09895 b7cf011e3bb5d7eeb08fb98797a9f845 987 Gene3D G3DSA:3.30.1490.20 781 844 3.5E-13 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CU254_RS09895 b7cf011e3bb5d7eeb08fb98797a9f845 987 SUPERFAMILY SSF56059 768 967 2.43E-22 T 28-03-2018 CU254_RS09895 b7cf011e3bb5d7eeb08fb98797a9f845 987 Gene3D G3DSA:3.40.50.720 294 415 6.4E-42 T 28-03-2018 CU254_RS17040 bd1533cfe79513d6bf1087f74334393d 335 Pfam PF00296 Luciferase-like monooxygenase 10 307 9.6E-45 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS17040 bd1533cfe79513d6bf1087f74334393d 335 Gene3D G3DSA:3.20.20.30 5 330 1.3E-54 T 28-03-2018 CU254_RS17040 bd1533cfe79513d6bf1087f74334393d 335 SUPERFAMILY SSF51679 8 324 1.91E-50 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS08810 4bca2f233f5f924f3c8e8ae22d1ef716 367 SUPERFAMILY SSF56752 6 363 5.89E-117 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CU254_RS08810 4bca2f233f5f924f3c8e8ae22d1ef716 367 PIRSF PIRSF006468 5 367 1.2E-131 T 28-03-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 CU254_RS08810 4bca2f233f5f924f3c8e8ae22d1ef716 367 Gene3D G3DSA:3.30.470.10 2 181 1.4E-68 T 28-03-2018 CU254_RS08810 4bca2f233f5f924f3c8e8ae22d1ef716 367 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 49 364 1.7E-133 T 28-03-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 CU254_RS08810 4bca2f233f5f924f3c8e8ae22d1ef716 367 Gene3D G3DSA:3.20.10.10 182 362 2.9E-51 T 28-03-2018 CU254_RS08810 4bca2f233f5f924f3c8e8ae22d1ef716 367 Pfam PF01063 Amino-transferase class IV 75 321 5.7E-32 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CU254_RS08810 4bca2f233f5f924f3c8e8ae22d1ef716 367 ProSitePatterns PS00770 Aminotransferases class-IV signature. 239 272 - T 28-03-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 CU254_RS13340 764e8635acf206009046c1c67de08de3 526 Gene3D G3DSA:3.20.20.70 131 523 5.3E-91 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS13340 764e8635acf206009046c1c67de08de3 526 SUPERFAMILY SSF51395 16 512 3.3E-128 T 28-03-2018 CU254_RS13340 764e8635acf206009046c1c67de08de3 526 PIRSF PIRSF006429 3 525 1.3E-157 T 28-03-2018 IPR024188 Glutamate synthase large subunit-like protein CU254_RS13340 764e8635acf206009046c1c67de08de3 526 PIRSF PIRSF500060 7 525 6.9E-226 T 28-03-2018 IPR027283 Glutamate synthase large subunit-like protein, bacteria CU254_RS13340 764e8635acf206009046c1c67de08de3 526 Pfam PF01645 Conserved region in glutamate synthase 155 470 5.8E-85 T 28-03-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 CU254_RS20500 af36e8dc56e5dd77692c6bdc8d9b9276 275 SUPERFAMILY SSF52096 20 271 1.33E-55 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS20500 af36e8dc56e5dd77692c6bdc8d9b9276 275 Gene3D G3DSA:3.90.226.10 21 229 2.0E-47 T 28-03-2018 CU254_RS20500 af36e8dc56e5dd77692c6bdc8d9b9276 275 Pfam PF00378 Enoyl-CoA hydratase/isomerase 25 263 1.1E-30 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CU254_RS20500 af36e8dc56e5dd77692c6bdc8d9b9276 275 Gene3D G3DSA:1.10.12.10 230 275 2.0E-6 T 28-03-2018 IPR014748 Crontonase, C-terminal CU254_RS17985 2a167c260d2ffc6dbe3560f1e2591df1 935 PRINTS PR00415 Aconitase family signature 168 176 2.4E-41 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CU254_RS17985 2a167c260d2ffc6dbe3560f1e2591df1 935 PRINTS PR00415 Aconitase family signature 144 157 2.4E-41 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CU254_RS17985 2a167c260d2ffc6dbe3560f1e2591df1 935 PRINTS PR00415 Aconitase family signature 211 226 2.4E-41 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CU254_RS17985 2a167c260d2ffc6dbe3560f1e2591df1 935 PRINTS PR00415 Aconitase family signature 273 286 2.4E-41 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CU254_RS17985 2a167c260d2ffc6dbe3560f1e2591df1 935 PRINTS PR00415 Aconitase family signature 197 210 2.4E-41 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CU254_RS17985 2a167c260d2ffc6dbe3560f1e2591df1 935 PRINTS PR00415 Aconitase family signature 468 479 2.4E-41 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CU254_RS17985 2a167c260d2ffc6dbe3560f1e2591df1 935 PRINTS PR00415 Aconitase family signature 530 543 2.4E-41 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CU254_RS17985 2a167c260d2ffc6dbe3560f1e2591df1 935 PRINTS PR00415 Aconitase family signature 366 380 2.4E-41 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CU254_RS17985 2a167c260d2ffc6dbe3560f1e2591df1 935 PRINTS PR00415 Aconitase family signature 287 300 2.4E-41 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CU254_RS17985 2a167c260d2ffc6dbe3560f1e2591df1 935 SUPERFAMILY SSF53732 7 400 1.27E-224 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CU254_RS17985 2a167c260d2ffc6dbe3560f1e2591df1 935 SUPERFAMILY SSF53732 438 664 1.27E-224 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CU254_RS17985 2a167c260d2ffc6dbe3560f1e2591df1 935 ProSitePatterns PS01244 Aconitase family signature 2. 530 543 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CU254_RS17985 2a167c260d2ffc6dbe3560f1e2591df1 935 Gene3D G3DSA:3.30.499.10 10 233 7.5E-73 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CU254_RS17985 2a167c260d2ffc6dbe3560f1e2591df1 935 Gene3D G3DSA:3.40.1060.10 234 365 8.6E-45 T 28-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CU254_RS17985 2a167c260d2ffc6dbe3560f1e2591df1 935 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 28 932 0.0 T 28-03-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 CU254_RS17985 2a167c260d2ffc6dbe3560f1e2591df1 935 Pfam PF00694 Aconitase C-terminal domain 729 858 5.0E-44 T 28-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 CU254_RS17985 2a167c260d2ffc6dbe3560f1e2591df1 935 SUPERFAMILY SSF52016 668 932 5.1E-84 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CU254_RS17985 2a167c260d2ffc6dbe3560f1e2591df1 935 Pfam PF00330 Aconitase family (aconitate hydratase) 67 599 4.6E-179 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CU254_RS17985 2a167c260d2ffc6dbe3560f1e2591df1 935 Gene3D G3DSA:3.20.19.10 690 934 1.4E-92 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CU254_RS17985 2a167c260d2ffc6dbe3560f1e2591df1 935 Gene3D G3DSA:3.30.499.10 366 613 1.0E-68 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CU254_RS17985 2a167c260d2ffc6dbe3560f1e2591df1 935 ProSitePatterns PS00450 Aconitase family signature 1. 464 480 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CU254_RS00045 c295a180169fbfd2226adca0eaa3a0c9 322 SUPERFAMILY SSF48179 172 257 1.81E-20 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CU254_RS00045 c295a180169fbfd2226adca0eaa3a0c9 322 Gene3D G3DSA:1.10.3660.10 179 281 2.4E-8 T 28-03-2018 CU254_RS00045 c295a180169fbfd2226adca0eaa3a0c9 322 Gene3D G3DSA:3.40.50.720 1 170 6.9E-25 T 28-03-2018 CU254_RS00045 c295a180169fbfd2226adca0eaa3a0c9 322 Pfam PF02153 Prephenate dehydrogenase 24 245 2.2E-44 T 28-03-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 CU254_RS00045 c295a180169fbfd2226adca0eaa3a0c9 322 SUPERFAMILY SSF51735 4 166 2.7E-29 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS16205 232c959821e9344c89bdb5f48c073637 287 SUPERFAMILY SSF52402 6 133 1.51E-18 T 28-03-2018 CU254_RS16205 232c959821e9344c89bdb5f48c073637 287 SUPERFAMILY SSF52402 144 284 1.51E-32 T 28-03-2018 CU254_RS16205 232c959821e9344c89bdb5f48c073637 287 Gene3D G3DSA:3.40.50.620 140 287 7.2E-32 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS16205 232c959821e9344c89bdb5f48c073637 287 Pfam PF00582 Universal stress protein family 145 282 1.3E-26 T 28-03-2018 IPR006016 UspA GO:0006950 CU254_RS16205 232c959821e9344c89bdb5f48c073637 287 Pfam PF00582 Universal stress protein family 5 131 7.7E-15 T 28-03-2018 IPR006016 UspA GO:0006950 CU254_RS16205 232c959821e9344c89bdb5f48c073637 287 Gene3D G3DSA:3.40.50.620 1 135 3.6E-19 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS16205 232c959821e9344c89bdb5f48c073637 287 PRINTS PR01438 Universal stress protein signature 242 254 3.2E-16 T 28-03-2018 IPR006015 Universal stress protein A CU254_RS16205 232c959821e9344c89bdb5f48c073637 287 PRINTS PR01438 Universal stress protein signature 260 282 3.2E-16 T 28-03-2018 IPR006015 Universal stress protein A CU254_RS16205 232c959821e9344c89bdb5f48c073637 287 PRINTS PR01438 Universal stress protein signature 142 160 3.2E-16 T 28-03-2018 IPR006015 Universal stress protein A CU254_RS22390 966f44c26c4cfed5df2a4852e50e4398 325 Gene3D G3DSA:3.40.50.1000 4 97 1.0E-8 T 28-03-2018 IPR023214 HAD-like domain CU254_RS22390 966f44c26c4cfed5df2a4852e50e4398 325 Pfam PF13242 HAD-hyrolase-like 185 257 5.8E-16 T 28-03-2018 CU254_RS22390 966f44c26c4cfed5df2a4852e50e4398 325 Gene3D G3DSA:3.40.50.1000 98 185 1.2E-21 T 28-03-2018 IPR023214 HAD-like domain CU254_RS22390 966f44c26c4cfed5df2a4852e50e4398 325 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 10 232 5.1E-36 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CU254_RS22390 966f44c26c4cfed5df2a4852e50e4398 325 SUPERFAMILY SSF56784 6 256 2.53E-56 T 28-03-2018 IPR023214 HAD-like domain CU254_RS22390 966f44c26c4cfed5df2a4852e50e4398 325 Pfam PF13344 Haloacid dehalogenase-like hydrolase 9 109 1.5E-23 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CU254_RS22390 966f44c26c4cfed5df2a4852e50e4398 325 PIRSF PIRSF000915 4 264 7.5E-63 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CU254_RS00120 c2f72b644e9ce39a4e25f5069274e047 451 PRINTS PR00145 Argininosuccinate lyase family signature 237 261 1.5E-8 T 28-03-2018 CU254_RS00120 c2f72b644e9ce39a4e25f5069274e047 451 PRINTS PR00145 Argininosuccinate lyase family signature 143 163 1.5E-8 T 28-03-2018 CU254_RS00120 c2f72b644e9ce39a4e25f5069274e047 451 PRINTS PR00145 Argininosuccinate lyase family signature 102 124 1.5E-8 T 28-03-2018 CU254_RS00120 c2f72b644e9ce39a4e25f5069274e047 451 PRINTS PR00145 Argininosuccinate lyase family signature 279 295 1.5E-8 T 28-03-2018 CU254_RS00120 c2f72b644e9ce39a4e25f5069274e047 451 Gene3D G3DSA:1.20.200.10 106 372 8.8E-89 T 28-03-2018 CU254_RS00120 c2f72b644e9ce39a4e25f5069274e047 451 Gene3D G3DSA:1.10.40.30 373 446 9.7E-23 T 28-03-2018 CU254_RS00120 c2f72b644e9ce39a4e25f5069274e047 451 PRINTS PR00149 Fumarate lyase superfamily signature 279 295 3.7E-21 T 28-03-2018 IPR000362 Fumarate lyase family CU254_RS00120 c2f72b644e9ce39a4e25f5069274e047 451 PRINTS PR00149 Fumarate lyase superfamily signature 237 264 3.7E-21 T 28-03-2018 IPR000362 Fumarate lyase family CU254_RS00120 c2f72b644e9ce39a4e25f5069274e047 451 PRINTS PR00149 Fumarate lyase superfamily signature 148 166 3.7E-21 T 28-03-2018 IPR000362 Fumarate lyase family CU254_RS00120 c2f72b644e9ce39a4e25f5069274e047 451 PRINTS PR00149 Fumarate lyase superfamily signature 103 121 3.7E-21 T 28-03-2018 IPR000362 Fumarate lyase family CU254_RS00120 c2f72b644e9ce39a4e25f5069274e047 451 ProSitePatterns PS00163 Fumarate lyases signature. 279 288 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CU254_RS00120 c2f72b644e9ce39a4e25f5069274e047 451 SUPERFAMILY SSF48557 21 447 1.88E-98 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 CU254_RS00120 c2f72b644e9ce39a4e25f5069274e047 451 Gene3D G3DSA:1.10.275.10 4 105 1.9E-14 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal CU254_RS00120 c2f72b644e9ce39a4e25f5069274e047 451 TIGRFAM TIGR02426 protocat_pcaB: 3-carboxy-cis,cis-muconate cycloisomerase 16 352 1.5E-110 T 28-03-2018 IPR012789 3-carboxy-cis,cis-muconate cycloisomerase GO:0019619|GO:0047472 KEGG: 00362+5.5.1.2 CU254_RS00120 c2f72b644e9ce39a4e25f5069274e047 451 Pfam PF10397 Adenylosuccinate lyase C-terminus 368 445 3.2E-15 T 28-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CU254_RS00120 c2f72b644e9ce39a4e25f5069274e047 451 SMART SM00998 367 446 4.6E-20 T 28-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CU254_RS00120 c2f72b644e9ce39a4e25f5069274e047 451 Pfam PF00206 Lyase 26 301 6.3E-47 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal CU254_RS25615 2fae7c36e319eb3927ce7e1e01a47f8c 192 Gene3D G3DSA:3.10.180.10 2 134 4.5E-14 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS25615 2fae7c36e319eb3927ce7e1e01a47f8c 192 SUPERFAMILY SSF54593 5 126 1.02E-16 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS34800 1bc5450559cfc8b0b2c9a7e88b624a3f 207 Pfam PF13649 Methyltransferase domain 60 154 3.1E-16 T 28-03-2018 CU254_RS34800 1bc5450559cfc8b0b2c9a7e88b624a3f 207 SUPERFAMILY SSF53335 45 196 8.14E-31 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS34800 1bc5450559cfc8b0b2c9a7e88b624a3f 207 Gene3D G3DSA:3.40.50.150 9 206 1.6E-28 T 28-03-2018 CU254_RS01250 53e2178257e2bf0b8f888371d67cac27 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 25 44 1.9E-7 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS01250 53e2178257e2bf0b8f888371d67cac27 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 14 25 1.9E-7 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS01250 53e2178257e2bf0b8f888371d67cac27 154 Pfam PF01037 Lrp/AsnC ligand binding domain 69 135 3.5E-17 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CU254_RS01250 53e2178257e2bf0b8f888371d67cac27 154 SMART SM00344 1 105 2.1E-35 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CU254_RS01250 53e2178257e2bf0b8f888371d67cac27 154 Gene3D G3DSA:3.30.70.920 51 142 1.4E-22 T 28-03-2018 CU254_RS01250 53e2178257e2bf0b8f888371d67cac27 154 ProSitePatterns PS00519 AsnC-type HTH domain signature. 16 42 - T 28-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site CU254_RS01250 53e2178257e2bf0b8f888371d67cac27 154 SUPERFAMILY SSF46785 1 57 1.24E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS01250 53e2178257e2bf0b8f888371d67cac27 154 Pfam PF13404 AsnC-type helix-turn-helix domain 1 39 9.3E-15 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS01250 53e2178257e2bf0b8f888371d67cac27 154 SUPERFAMILY SSF54909 59 140 1.61E-16 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS01250 53e2178257e2bf0b8f888371d67cac27 154 Gene3D G3DSA:1.10.10.10 1 50 7.2E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS12345 045ebf40387d508cdca571a033573628 266 Gene3D G3DSA:3.40.50.850 21 263 9.9E-52 T 28-03-2018 CU254_RS12345 045ebf40387d508cdca571a033573628 266 SUPERFAMILY SSF52499 48 246 9.68E-55 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CU254_RS12345 045ebf40387d508cdca571a033573628 266 Pfam PF00857 Isochorismatase family 62 238 9.6E-41 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CU254_RS22245 11242c742a48fb567692e23714c67ec3 493 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 48 475 1.0E-152 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 CU254_RS22245 11242c742a48fb567692e23714c67ec3 493 SUPERFAMILY SSF52540 49 216 2.06E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS22245 11242c742a48fb567692e23714c67ec3 493 PIRSF PIRSF006485 46 483 3.3E-157 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 CU254_RS22245 11242c742a48fb567692e23714c67ec3 493 SUPERFAMILY SSF52540 182 479 5.95E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS22245 11242c742a48fb567692e23714c67ec3 493 Gene3D G3DSA:1.20.120.430 288 397 5.0E-13 T 28-03-2018 CU254_RS22245 11242c742a48fb567692e23714c67ec3 493 Gene3D G3DSA:3.30.300.20 398 476 7.2E-27 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CU254_RS22245 11242c742a48fb567692e23714c67ec3 493 Hamap MF_00195 GTPase Der [der]. 47 478 34.632 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 CU254_RS22245 11242c742a48fb567692e23714c67ec3 493 SMART SM00382 220 460 0.74 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS22245 11242c742a48fb567692e23714c67ec3 493 SMART SM00382 46 182 0.3 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS22245 11242c742a48fb567692e23714c67ec3 493 Pfam PF01926 50S ribosome-binding GTPase 50 164 2.2E-23 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CU254_RS22245 11242c742a48fb567692e23714c67ec3 493 Pfam PF01926 50S ribosome-binding GTPase 223 341 1.2E-20 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CU254_RS22245 11242c742a48fb567692e23714c67ec3 493 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 222 353 2.6E-21 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CU254_RS22245 11242c742a48fb567692e23714c67ec3 493 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 48 169 9.9E-22 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CU254_RS22245 11242c742a48fb567692e23714c67ec3 493 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 224 244 1.1E-6 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CU254_RS22245 11242c742a48fb567692e23714c67ec3 493 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 273 288 1.1E-6 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CU254_RS22245 11242c742a48fb567692e23714c67ec3 493 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 397 475 6.6E-24 T 28-03-2018 IPR032859 GTPase Der, C-terminal KH-domain-like CU254_RS22245 11242c742a48fb567692e23714c67ec3 493 Gene3D G3DSA:1.20.120.430 5 113 2.4E-18 T 28-03-2018 CU254_RS22245 11242c742a48fb567692e23714c67ec3 493 Gene3D G3DSA:1.20.120.430 114 287 1.8E-38 T 28-03-2018 CU254_RS06220 1bf6f908f8bbdc67e017ec2dac57b9de 207 ProSitePatterns PS01081 TetR-type HTH domain signature. 30 60 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CU254_RS06220 1bf6f908f8bbdc67e017ec2dac57b9de 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 64 7.2E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS06220 1bf6f908f8bbdc67e017ec2dac57b9de 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 2.5E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS06220 1bf6f908f8bbdc67e017ec2dac57b9de 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 2.5E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS06220 1bf6f908f8bbdc67e017ec2dac57b9de 207 Gene3D G3DSA:1.10.357.10 1 205 3.1E-35 T 28-03-2018 CU254_RS06220 1bf6f908f8bbdc67e017ec2dac57b9de 207 SUPERFAMILY SSF46689 5 80 3.9E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS34115 466e589b539274520bd31b7b900d17c9 152 Pfam PF16708 Lipoprotein confined to pathogenic Mycobacterium 2 137 3.5E-22 T 28-03-2018 IPR032018 Putative lipoprotein, pathogenic bacteria CU254_RS02185 26e40c7507fdfd8254e88399504d377f 96 SUPERFAMILY SSF140453 5 96 5.23E-23 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CU254_RS02185 26e40c7507fdfd8254e88399504d377f 96 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 6 93 7.3E-23 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CU254_RS02185 26e40c7507fdfd8254e88399504d377f 96 Pfam PF06013 Proteins of 100 residues with WXG 6 90 1.4E-17 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CU254_RS02185 26e40c7507fdfd8254e88399504d377f 96 Gene3D G3DSA:1.10.287.1060 2 96 7.2E-23 T 28-03-2018 CU254_RS04540 137826da6129634ac0d326f3ae621996 723 SUPERFAMILY SSF56003 112 721 1.7E-154 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CU254_RS04540 137826da6129634ac0d326f3ae621996 723 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 155 664 4.7E-118 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CU254_RS04540 137826da6129634ac0d326f3ae621996 723 SMART SM01008 12 120 2.0E-36 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CU254_RS04540 137826da6129634ac0d326f3ae621996 723 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 12 120 5.9E-24 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CU254_RS04540 137826da6129634ac0d326f3ae621996 723 Gene3D G3DSA:3.30.365.10 258 422 1.7E-36 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CU254_RS04540 137826da6129634ac0d326f3ae621996 723 Gene3D G3DSA:3.30.365.10 570 722 3.3E-44 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CU254_RS04540 137826da6129634ac0d326f3ae621996 723 Gene3D G3DSA:3.90.1170.50 2 120 1.0E-30 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CU254_RS04540 137826da6129634ac0d326f3ae621996 723 Gene3D G3DSA:3.30.365.10 423 569 9.4E-26 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CU254_RS04540 137826da6129634ac0d326f3ae621996 723 Gene3D G3DSA:3.30.365.10 152 257 1.2E-31 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CU254_RS04540 137826da6129634ac0d326f3ae621996 723 SUPERFAMILY SSF54665 3 131 1.57E-35 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CU254_RS18055 1c0d15d59aee9ad15a27573a38f0c386 440 ProSitePatterns PS00216 Sugar transport proteins signature 1. 80 96 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CU254_RS18055 1c0d15d59aee9ad15a27573a38f0c386 440 ProSitePatterns PS00216 Sugar transport proteins signature 1. 302 319 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CU254_RS18055 1c0d15d59aee9ad15a27573a38f0c386 440 ProSitePatterns PS00217 Sugar transport proteins signature 2. 130 155 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CU254_RS18055 1c0d15d59aee9ad15a27573a38f0c386 440 SUPERFAMILY SSF103473 20 435 8.63E-66 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS18055 1c0d15d59aee9ad15a27573a38f0c386 440 Gene3D G3DSA:1.20.1250.20 233 440 1.4E-24 T 28-03-2018 CU254_RS18055 1c0d15d59aee9ad15a27573a38f0c386 440 Gene3D G3DSA:1.20.1250.20 19 229 3.7E-25 T 28-03-2018 CU254_RS18055 1c0d15d59aee9ad15a27573a38f0c386 440 Pfam PF07690 Major Facilitator Superfamily 58 372 1.4E-27 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS24640 be3ebc6f903dd5acc601c131f8712043 232 Pfam PF14011 EspG family 5 226 5.7E-53 T 28-03-2018 IPR025734 EspG family CU254_RS35360 386aced8d17e9f80a8f5aba7794ff236 253 Pfam PF14062 Domain of unknown function (DUF4253) 145 252 1.1E-28 T 28-03-2018 IPR025349 Domain of unknown function DUF4253 CU254_RS07905 056bd2d5e3b14148c40628ddff226455 277 PIRSF PIRSF018249 2 273 1.9E-70 T 28-03-2018 IPR016718 rRNA (guanine-N1-)-methyltransferase A, predicted GO:0008168 CU254_RS07905 056bd2d5e3b14148c40628ddff226455 277 SUPERFAMILY SSF53335 13 255 1.18E-22 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS07905 056bd2d5e3b14148c40628ddff226455 277 Gene3D G3DSA:3.40.50.150 9 274 6.2E-36 T 28-03-2018 CU254_RS03960 eb8e140eac444dd2145c1519979766e5 264 Pfam PF00440 Bacterial regulatory proteins, tetR family 49 93 1.8E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS03960 eb8e140eac444dd2145c1519979766e5 264 SUPERFAMILY SSF48498 117 227 3.56E-17 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS03960 eb8e140eac444dd2145c1519979766e5 264 Gene3D G3DSA:1.10.357.10 91 232 5.5E-20 T 28-03-2018 CU254_RS03960 eb8e140eac444dd2145c1519979766e5 264 SUPERFAMILY SSF46689 34 115 3.2E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS03960 eb8e140eac444dd2145c1519979766e5 264 Gene3D G3DSA:1.10.10.60 10 90 5.8E-18 T 28-03-2018 CU254_RS03960 eb8e140eac444dd2145c1519979766e5 264 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 68 91 2.3E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS03960 eb8e140eac444dd2145c1519979766e5 264 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 61 2.3E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS28985 3c71cee4fc2eba8c6161ad99320e1d32 300 SUPERFAMILY SSF51735 109 296 5.61E-24 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS28985 3c71cee4fc2eba8c6161ad99320e1d32 300 Gene3D G3DSA:3.90.180.10 234 298 2.6E-4 T 28-03-2018 CU254_RS28985 3c71cee4fc2eba8c6161ad99320e1d32 300 Pfam PF13602 Zinc-binding dehydrogenase 178 297 1.8E-13 T 28-03-2018 CU254_RS28985 3c71cee4fc2eba8c6161ad99320e1d32 300 SMART SM00829 10 297 4.4E-14 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CU254_RS28985 3c71cee4fc2eba8c6161ad99320e1d32 300 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 86 1.7E-14 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CU254_RS28985 3c71cee4fc2eba8c6161ad99320e1d32 300 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 60 74 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CU254_RS28985 3c71cee4fc2eba8c6161ad99320e1d32 300 Gene3D G3DSA:3.40.50.720 146 233 2.5E-12 T 28-03-2018 CU254_RS28985 3c71cee4fc2eba8c6161ad99320e1d32 300 Gene3D G3DSA:3.90.180.10 1 145 4.2E-43 T 28-03-2018 CU254_RS28985 3c71cee4fc2eba8c6161ad99320e1d32 300 SUPERFAMILY SSF50129 2 141 5.02E-34 T 28-03-2018 IPR011032 GroES-like CU254_RS30985 0994992a22d1eda30667b32c5f01bf0f 92 SUPERFAMILY SSF54285 1 90 6.83E-24 T 28-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp CU254_RS30985 0994992a22d1eda30667b32c5f01bf0f 92 Pfam PF02597 ThiS family 5 90 9.0E-19 T 28-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 CU254_RS30985 0994992a22d1eda30667b32c5f01bf0f 92 Gene3D G3DSA:3.10.20.30 1 91 1.1E-22 T 28-03-2018 IPR012675 Beta-grasp domain CU254_RS10625 5f7a319bc0d2c5bea033e2ebb5e9e8da 126 Pfam PF13564 DoxX-like family 8 121 1.5E-20 T 28-03-2018 IPR032808 DoxX family CU254_RS26750 66f70c3adc582b5fb74d6472151dcbdb 242 Gene3D G3DSA:3.40.50.1110 2 240 9.8E-21 T 28-03-2018 CU254_RS26750 66f70c3adc582b5fb74d6472151dcbdb 242 SUPERFAMILY SSF52266 3 91 1.3E-14 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CU254_RS26750 66f70c3adc582b5fb74d6472151dcbdb 242 SUPERFAMILY SSF52266 131 236 1.3E-14 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CU254_RS26750 66f70c3adc582b5fb74d6472151dcbdb 242 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 7 223 4.4E-11 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CU254_RS36785 72ac1d56e926f88f5cbd9766dba28dd9 84 SUPERFAMILY SSF52833 6 70 6.58E-13 T 28-03-2018 IPR012336 Thioredoxin-like fold CU254_RS36785 72ac1d56e926f88f5cbd9766dba28dd9 84 Pfam PF00462 Glutaredoxin 6 62 1.4E-11 T 28-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 CU254_RS36785 72ac1d56e926f88f5cbd9766dba28dd9 84 Gene3D G3DSA:3.40.30.10 1 84 8.9E-12 T 28-03-2018 CU254_RS34445 08518d388c1527e1c23586d8ab22f53a 387 SUPERFAMILY SSF56645 1 191 2.75E-25 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS34445 08518d388c1527e1c23586d8ab22f53a 387 SUPERFAMILY SSF47203 223 356 2.26E-24 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS34445 08518d388c1527e1c23586d8ab22f53a 387 Gene3D G3DSA:1.20.140.10 219 354 1.7E-27 T 28-03-2018 CU254_RS34445 08518d388c1527e1c23586d8ab22f53a 387 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 222 368 1.0E-19 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS34445 08518d388c1527e1c23586d8ab22f53a 387 Gene3D G3DSA:1.10.540.10 1 119 9.6E-15 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS34445 08518d388c1527e1c23586d8ab22f53a 387 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 117 7.9E-10 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS15680 55780c7bcc78b5b2d93cbfab14b84f43 239 SUPERFAMILY SSF53474 3 236 2.38E-31 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS15680 55780c7bcc78b5b2d93cbfab14b84f43 239 Pfam PF12697 Alpha/beta hydrolase family 4 233 1.9E-19 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS15680 55780c7bcc78b5b2d93cbfab14b84f43 239 PRINTS PR00412 Epoxide hydrolase signature 28 43 7.4E-7 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS15680 55780c7bcc78b5b2d93cbfab14b84f43 239 PRINTS PR00412 Epoxide hydrolase signature 85 98 7.4E-7 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS15680 55780c7bcc78b5b2d93cbfab14b84f43 239 PRINTS PR00412 Epoxide hydrolase signature 8 26 7.4E-7 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS15680 55780c7bcc78b5b2d93cbfab14b84f43 239 PRINTS PR00412 Epoxide hydrolase signature 71 84 7.4E-7 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS15680 55780c7bcc78b5b2d93cbfab14b84f43 239 Gene3D G3DSA:3.40.50.1820 1 238 5.4E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS15680 55780c7bcc78b5b2d93cbfab14b84f43 239 PRINTS PR00111 Alpha/beta hydrolase fold signature 28 43 1.1E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS15680 55780c7bcc78b5b2d93cbfab14b84f43 239 PRINTS PR00111 Alpha/beta hydrolase fold signature 71 84 1.1E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS15680 55780c7bcc78b5b2d93cbfab14b84f43 239 PRINTS PR00111 Alpha/beta hydrolase fold signature 85 98 1.1E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS14470 b84da834a6b6d08d1877afb037b0567f 315 SUPERFAMILY SSF51412 1 311 4.58E-50 T 28-03-2018 CU254_RS14470 b84da834a6b6d08d1877afb037b0567f 315 Pfam PF03060 Nitronate monooxygenase 3 73 2.6E-10 T 28-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CU254_RS14470 b84da834a6b6d08d1877afb037b0567f 315 Pfam PF03060 Nitronate monooxygenase 81 304 9.0E-38 T 28-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CU254_RS14470 b84da834a6b6d08d1877afb037b0567f 315 Gene3D G3DSA:3.20.20.70 1 313 6.0E-44 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS31315 cd6091eba711413233fa79a532baa010 393 Gene3D G3DSA:2.120.10.30 36 387 2.2E-4 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CU254_RS32815 6bbcfb1df3c131d978b2f7c86d944450 465 Pfam PF00206 Lyase 14 338 3.7E-100 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal CU254_RS32815 6bbcfb1df3c131d978b2f7c86d944450 465 Gene3D G3DSA:1.10.40.30 415 465 4.3E-24 T 28-03-2018 CU254_RS32815 6bbcfb1df3c131d978b2f7c86d944450 465 PRINTS PR00145 Argininosuccinate lyase family signature 171 191 8.1E-7 T 28-03-2018 CU254_RS32815 6bbcfb1df3c131d978b2f7c86d944450 465 PRINTS PR00145 Argininosuccinate lyase family signature 313 329 8.1E-7 T 28-03-2018 CU254_RS32815 6bbcfb1df3c131d978b2f7c86d944450 465 PRINTS PR00145 Argininosuccinate lyase family signature 129 151 8.1E-7 T 28-03-2018 CU254_RS32815 6bbcfb1df3c131d978b2f7c86d944450 465 SUPERFAMILY SSF48557 6 460 1.73E-141 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 CU254_RS32815 6bbcfb1df3c131d978b2f7c86d944450 465 ProSitePatterns PS00163 Fumarate lyases signature. 313 322 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CU254_RS32815 6bbcfb1df3c131d978b2f7c86d944450 465 Hamap MF_00743 Fumarate hydratase class II [fumC]. 6 463 80.353 T 28-03-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CU254_RS32815 6bbcfb1df3c131d978b2f7c86d944450 465 Pfam PF10415 Fumarase C C-terminus 404 461 3.7E-22 T 28-03-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CU254_RS32815 6bbcfb1df3c131d978b2f7c86d944450 465 Gene3D G3DSA:1.20.200.10 135 414 2.5E-77 T 28-03-2018 CU254_RS32815 6bbcfb1df3c131d978b2f7c86d944450 465 Gene3D G3DSA:1.10.275.10 4 134 4.9E-55 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal CU254_RS32815 6bbcfb1df3c131d978b2f7c86d944450 465 PRINTS PR00149 Fumarate lyase superfamily signature 176 194 6.6E-33 T 28-03-2018 IPR000362 Fumarate lyase family CU254_RS32815 6bbcfb1df3c131d978b2f7c86d944450 465 PRINTS PR00149 Fumarate lyase superfamily signature 130 148 6.6E-33 T 28-03-2018 IPR000362 Fumarate lyase family CU254_RS32815 6bbcfb1df3c131d978b2f7c86d944450 465 PRINTS PR00149 Fumarate lyase superfamily signature 267 294 6.6E-33 T 28-03-2018 IPR000362 Fumarate lyase family CU254_RS32815 6bbcfb1df3c131d978b2f7c86d944450 465 PRINTS PR00149 Fumarate lyase superfamily signature 313 329 6.6E-33 T 28-03-2018 IPR000362 Fumarate lyase family CU254_RS09530 97b8ce61015699c471e6864e101807f4 1553 SMART SM00490 319 429 6.4E-15 T 28-03-2018 IPR001650 Helicase, C-terminal CU254_RS09530 97b8ce61015699c471e6864e101807f4 1553 Gene3D G3DSA:3.40.50.300 12 250 5.1E-35 T 28-03-2018 CU254_RS09530 97b8ce61015699c471e6864e101807f4 1553 Pfam PF00271 Helicase conserved C-terminal domain 362 429 2.7E-13 T 28-03-2018 IPR001650 Helicase, C-terminal CU254_RS09530 97b8ce61015699c471e6864e101807f4 1553 Pfam PF08494 DEAD/H associated 692 885 1.8E-73 T 28-03-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 CU254_RS09530 97b8ce61015699c471e6864e101807f4 1553 Pfam PF00270 DEAD/DEAH box helicase 29 212 1.5E-23 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CU254_RS09530 97b8ce61015699c471e6864e101807f4 1553 SUPERFAMILY SSF52540 284 331 1.7E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS09530 97b8ce61015699c471e6864e101807f4 1553 SUPERFAMILY SSF52540 38 214 1.7E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS09530 97b8ce61015699c471e6864e101807f4 1553 SUPERFAMILY SSF52540 360 433 1.7E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS09530 97b8ce61015699c471e6864e101807f4 1553 SMART SM00382 41 416 0.0032 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS09530 97b8ce61015699c471e6864e101807f4 1553 Gene3D G3DSA:3.40.50.300 285 441 1.9E-27 T 28-03-2018 CU254_RS09530 97b8ce61015699c471e6864e101807f4 1553 Gene3D G3DSA:1.10.10.10 1030 1098 0.0092 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS09530 97b8ce61015699c471e6864e101807f4 1553 SMART SM00487 24 241 8.4E-35 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CU254_RS26865 54406e97025eb71762e6e9f31a129761 313 Gene3D G3DSA:3.40.50.300 8 284 6.4E-69 T 28-03-2018 CU254_RS26865 54406e97025eb71762e6e9f31a129761 313 SMART SM00382 35 218 3.0E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS26865 54406e97025eb71762e6e9f31a129761 313 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS26865 54406e97025eb71762e6e9f31a129761 313 Pfam PF00005 ABC transporter 27 169 3.9E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS26865 54406e97025eb71762e6e9f31a129761 313 SUPERFAMILY SSF52540 10 233 3.03E-66 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS28745 bbb2a2f28f63ece75277ef1384569952 228 SUPERFAMILY SSF46894 151 211 6.12E-5 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS28745 bbb2a2f28f63ece75277ef1384569952 228 Gene3D G3DSA:1.10.10.10 38 214 0.0015 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS40900 a888bf9dc71e7233cb45b87b4220df80 132 Gene3D G3DSA:1.10.10.60 8 79 1.6E-5 T 28-03-2018 CU254_RS40900 a888bf9dc71e7233cb45b87b4220df80 132 SUPERFAMILY SSF46955 66 120 6.23E-6 T 28-03-2018 IPR009061 Putative DNA-binding domain CU254_RS40900 a888bf9dc71e7233cb45b87b4220df80 132 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 67 108 1.5E-13 T 28-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 CU254_RS40900 a888bf9dc71e7233cb45b87b4220df80 132 Pfam PF12728 Helix-turn-helix domain 67 112 2.3E-11 T 28-03-2018 CU254_RS40900 a888bf9dc71e7233cb45b87b4220df80 132 Gene3D G3DSA:1.10.10.10 80 123 1.8E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS14330 14ecb46b9732f4909d4c630ffc08bf20 251 Gene3D G3DSA:3.40.50.1820 5 248 4.7E-32 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS14330 14ecb46b9732f4909d4c630ffc08bf20 251 Pfam PF00561 alpha/beta hydrolase fold 27 117 6.8E-16 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS14330 14ecb46b9732f4909d4c630ffc08bf20 251 SUPERFAMILY SSF53474 7 245 9.41E-37 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS35975 a82f20ea8cbd02095c7ce502721017aa 214 Gene3D G3DSA:3.90.550.10 12 209 6.8E-16 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS35975 a82f20ea8cbd02095c7ce502721017aa 214 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 20 205 5.1E-31 T 28-03-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CU254_RS35975 a82f20ea8cbd02095c7ce502721017aa 214 SUPERFAMILY SSF53448 21 204 3.75E-21 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS18665 663ea592600b53540fc63ec6716f17cf 524 SUPERFAMILY SSF51905 7 183 1.25E-60 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS18665 663ea592600b53540fc63ec6716f17cf 524 SUPERFAMILY SSF51905 272 360 1.25E-60 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS18665 663ea592600b53540fc63ec6716f17cf 524 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 8 30 2.4E-35 T 28-03-2018 CU254_RS18665 663ea592600b53540fc63ec6716f17cf 524 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 300 316 2.4E-35 T 28-03-2018 CU254_RS18665 663ea592600b53540fc63ec6716f17cf 524 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 285 300 2.4E-35 T 28-03-2018 CU254_RS18665 663ea592600b53540fc63ec6716f17cf 524 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 318 336 2.4E-35 T 28-03-2018 CU254_RS18665 663ea592600b53540fc63ec6716f17cf 524 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 162 177 2.4E-35 T 28-03-2018 CU254_RS18665 663ea592600b53540fc63ec6716f17cf 524 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 336 352 2.4E-35 T 28-03-2018 CU254_RS18665 663ea592600b53540fc63ec6716f17cf 524 Gene3D G3DSA:3.50.50.60 2 377 7.7E-59 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS18665 663ea592600b53540fc63ec6716f17cf 524 Pfam PF01494 FAD binding domain 7 345 1.4E-72 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CU254_RS38355 ce8d69e8d617fda37a34f83ac212588a 763 Gene3D G3DSA:1.10.1060.10 259 427 3.7E-33 T 28-03-2018 CU254_RS38355 ce8d69e8d617fda37a34f83ac212588a 763 Pfam PF02754 Cysteine-rich domain 472 563 6.0E-15 T 28-03-2018 IPR004017 Cysteine-rich domain CU254_RS38355 ce8d69e8d617fda37a34f83ac212588a 763 Pfam PF02754 Cysteine-rich domain 602 688 9.4E-17 T 28-03-2018 IPR004017 Cysteine-rich domain CU254_RS38355 ce8d69e8d617fda37a34f83ac212588a 763 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 390 401 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CU254_RS38355 ce8d69e8d617fda37a34f83ac212588a 763 Gene3D G3DSA:1.20.950.20 10 246 3.0E-30 T 28-03-2018 CU254_RS38355 ce8d69e8d617fda37a34f83ac212588a 763 Pfam PF13183 4Fe-4S dicluster domain 296 404 2.0E-13 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CU254_RS38355 ce8d69e8d617fda37a34f83ac212588a 763 SUPERFAMILY SSF46548 281 320 6.8E-22 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CU254_RS38355 ce8d69e8d617fda37a34f83ac212588a 763 SUPERFAMILY SSF46548 373 418 6.8E-22 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CU254_RS11540 d5658f5ca0c8739557f9deb4c09ea874 355 SUPERFAMILY SSF47413 7 66 2.65E-5 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS11540 d5658f5ca0c8739557f9deb4c09ea874 355 Gene3D G3DSA:1.10.10.10 37 198 6.2E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS11540 d5658f5ca0c8739557f9deb4c09ea874 355 Pfam PF13560 Helix-turn-helix domain 7 65 1.0E-6 T 28-03-2018 CU254_RS11540 d5658f5ca0c8739557f9deb4c09ea874 355 Gene3D G3DSA:1.10.10.60 7 36 1.3E-6 T 28-03-2018 CU254_RS17760 97b5090d5f6af2e81ce43f2968201533 417 Gene3D G3DSA:3.40.50.2000 221 408 2.4E-6 T 28-03-2018 CU254_RS17760 97b5090d5f6af2e81ce43f2968201533 417 Pfam PF04230 Polysaccharide pyruvyl transferase 14 352 8.2E-30 T 28-03-2018 IPR007345 Polysaccharide pyruvyl transferase CU254_RS17760 97b5090d5f6af2e81ce43f2968201533 417 SUPERFAMILY SSF53756 145 354 1.65E-6 T 28-03-2018 CU254_RS18495 b933e0daab0e255d41cc2e772f74f6a2 313 Gene3D G3DSA:1.10.3720.10 3 300 2.0E-39 T 28-03-2018 CU254_RS18495 b933e0daab0e255d41cc2e772f74f6a2 313 SUPERFAMILY SSF161098 92 299 6.54E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS18495 b933e0daab0e255d41cc2e772f74f6a2 313 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 311 2.0E-36 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS25240 d630aee5f175eea709dd965d8aa15490 3729 SUPERFAMILY SSF53448 2854 3212 1.55E-38 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS25240 d630aee5f175eea709dd965d8aa15490 3729 Gene3D G3DSA:1.20.1170.10 2301 2540 0.001 T 28-03-2018 CU254_RS25240 d630aee5f175eea709dd965d8aa15490 3729 Pfam PF12919 TcdA/TcdB catalytic glycosyltransferase domain 2991 3104 1.4E-5 T 28-03-2018 IPR024770 TcdA/TcdB toxin, catalytic glycosyltransferase domain GO:0016757 CU254_RS08000 dc2744a29261900d20c3920f821c9a99 262 Hamap MF_00052_B Ribonuclease HII [rnhB]. 21 202 33.845 T 28-03-2018 IPR022898 Ribonuclease HII GO:0004523 CU254_RS08000 dc2744a29261900d20c3920f821c9a99 262 Gene3D G3DSA:3.30.420.10 9 217 5.6E-56 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS08000 dc2744a29261900d20c3920f821c9a99 262 SUPERFAMILY SSF53098 15 205 5.46E-55 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS08000 dc2744a29261900d20c3920f821c9a99 262 Pfam PF01351 Ribonuclease HII 23 202 7.4E-31 T 28-03-2018 IPR024567 Ribonuclease HII/HIII domain CU254_RS22765 972a95adf7fd0a4e0b3515a91b79a035 90 Pfam PF07704 Rv0623-like transcription factor 1 72 1.4E-17 T 28-03-2018 IPR011660 Antitoxin VapB-like CU254_RS11695 01a626615cb9114a075a6184a9e91286 114 Pfam PF13397 RNA polymerase-binding protein 5 108 3.8E-43 T 28-03-2018 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 CU254_RS11695 01a626615cb9114a075a6184a9e91286 114 Hamap MF_01483 RNA polymerase-binding protein RbpA [rbpA]. 17 113 25.174 T 28-03-2018 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 CU254_RS11695 01a626615cb9114a075a6184a9e91286 114 ProSitePatterns PS00202 Rubredoxin signature. 51 61 - T 28-03-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 CU254_RS11445 3fa6ad013c0866b69e07bbcbee38bc01 363 PRINTS PR00599 Methionine aminopeptidase-1 signature 195 208 1.6E-6 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CU254_RS11445 3fa6ad013c0866b69e07bbcbee38bc01 363 PRINTS PR00599 Methionine aminopeptidase-1 signature 217 233 1.6E-6 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CU254_RS11445 3fa6ad013c0866b69e07bbcbee38bc01 363 PRINTS PR00599 Methionine aminopeptidase-1 signature 315 327 1.6E-6 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CU254_RS11445 3fa6ad013c0866b69e07bbcbee38bc01 363 SUPERFAMILY SSF53092 6 133 4.06E-21 T 28-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal CU254_RS11445 3fa6ad013c0866b69e07bbcbee38bc01 363 Gene3D G3DSA:3.90.230.10 118 363 1.8E-82 T 28-03-2018 CU254_RS11445 3fa6ad013c0866b69e07bbcbee38bc01 363 Gene3D G3DSA:3.40.350.10 2 117 4.2E-24 T 28-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CU254_RS11445 3fa6ad013c0866b69e07bbcbee38bc01 363 Pfam PF00557 Metallopeptidase family M24 143 346 8.8E-66 T 28-03-2018 IPR000994 Peptidase M24 CU254_RS11445 3fa6ad013c0866b69e07bbcbee38bc01 363 SUPERFAMILY SSF55920 135 361 1.44E-75 T 28-03-2018 IPR000994 Peptidase M24 CU254_RS11445 3fa6ad013c0866b69e07bbcbee38bc01 363 Pfam PF01321 Creatinase/Prolidase N-terminal domain 8 135 4.6E-21 T 28-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 CU254_RS11445 3fa6ad013c0866b69e07bbcbee38bc01 363 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 293 305 - T 28-03-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site CU254_RS15545 cf6c583e1a7dcac02c297083157b2a2e 163 Pfam PF07681 DoxX 16 92 2.7E-10 T 28-03-2018 IPR032808 DoxX family CU254_RS34005 76f1dd8de26e0c1c789aea42df0f77f3 550 Pfam PF00682 HMGL-like 33 310 2.1E-64 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CU254_RS34005 76f1dd8de26e0c1c789aea42df0f77f3 550 Gene3D G3DSA:3.20.20.70 8 383 1.4E-104 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS34005 76f1dd8de26e0c1c789aea42df0f77f3 550 Pfam PF08502 LeuA allosteric (dimerisation) domain 429 549 3.0E-16 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CU254_RS34005 76f1dd8de26e0c1c789aea42df0f77f3 550 Hamap MF_00572 2-isopropylmalate synthase [leuA]. 3 550 49.446 T 28-03-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CU254_RS34005 76f1dd8de26e0c1c789aea42df0f77f3 550 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 38 54 - T 28-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CU254_RS34005 76f1dd8de26e0c1c789aea42df0f77f3 550 SMART SM00917 429 550 4.9E-9 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CU254_RS34005 76f1dd8de26e0c1c789aea42df0f77f3 550 SUPERFAMILY SSF51569 20 327 2.93E-90 T 28-03-2018 CU254_RS34005 76f1dd8de26e0c1c789aea42df0f77f3 550 SUPERFAMILY SSF110921 457 550 8.11E-19 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CU254_RS34005 76f1dd8de26e0c1c789aea42df0f77f3 550 SUPERFAMILY SSF89000 395 444 5.1E-14 T 28-03-2018 CU254_RS34005 76f1dd8de26e0c1c789aea42df0f77f3 550 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 240 253 - T 28-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CU254_RS37930 82e4c8211f447cfe46e97c268d87ca6e 165 Gene3D G3DSA:3.30.300.20 9 165 5.8E-37 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CU254_RS37930 82e4c8211f447cfe46e97c268d87ca6e 165 SUPERFAMILY SSF82784 7 164 3.4E-41 T 28-03-2018 IPR003718 OsmC/Ohr family CU254_RS37930 82e4c8211f447cfe46e97c268d87ca6e 165 Pfam PF02566 OsmC-like protein 58 162 3.4E-23 T 28-03-2018 IPR003718 OsmC/Ohr family CU254_RS36725 707d84c44c39aeada3f16ca36389c80a 394 Pfam PF06965 Na+/H+ antiporter 1 12 383 2.0E-131 T 28-03-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 CU254_RS36725 707d84c44c39aeada3f16ca36389c80a 394 TIGRFAM TIGR00773 NhaA: Na+/H+ antiporter NhaA 13 382 3.3E-104 T 28-03-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 CU254_RS36725 707d84c44c39aeada3f16ca36389c80a 394 Hamap MF_01844 Na(+)/H(+) antiporter NhaA [nhaA]. 10 389 20.751 T 28-03-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 CU254_RS36725 707d84c44c39aeada3f16ca36389c80a 394 Gene3D G3DSA:1.20.1530.10 8 389 5.4E-134 T 28-03-2018 IPR023171 Na/H antiporter domain CU254_RS24170 4af8dfbe865d735e6494c1643ba4e431 139 Gene3D G3DSA:2.40.50.140 55 118 3.5E-9 T 28-03-2018 CU254_RS24170 4af8dfbe865d735e6494c1643ba4e431 139 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 52 115 1.4E-12 T 28-03-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal CU254_RS24170 4af8dfbe865d735e6494c1643ba4e431 139 SUPERFAMILY SSF50249 9 118 1.88E-11 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CU254_RS07480 890c654b253bbab1e48410a762a54ad7 500 SMART SM00382 30 226 5.6E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS07480 890c654b253bbab1e48410a762a54ad7 500 SMART SM00382 282 475 0.32 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS07480 890c654b253bbab1e48410a762a54ad7 500 Pfam PF00005 ABC transporter 21 170 6.5E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS07480 890c654b253bbab1e48410a762a54ad7 500 Pfam PF00005 ABC transporter 274 428 1.8E-18 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS07480 890c654b253bbab1e48410a762a54ad7 500 Gene3D G3DSA:3.40.50.300 2 253 1.7E-52 T 28-03-2018 CU254_RS07480 890c654b253bbab1e48410a762a54ad7 500 ProSitePatterns PS00211 ABC transporters family signature. 400 414 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS07480 890c654b253bbab1e48410a762a54ad7 500 SUPERFAMILY SSF52540 4 229 2.34E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS07480 890c654b253bbab1e48410a762a54ad7 500 Gene3D G3DSA:3.40.50.300 266 483 1.9E-33 T 28-03-2018 CU254_RS07480 890c654b253bbab1e48410a762a54ad7 500 SUPERFAMILY SSF52540 273 479 1.36E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS12965 949d6793524935fac041ad36a01931f5 73 Pfam PF03621 MbtH-like protein 2 52 9.4E-29 T 28-03-2018 IPR005153 MbtH-like protein CU254_RS12965 949d6793524935fac041ad36a01931f5 73 Gene3D G3DSA:3.90.820.10 2 68 3.0E-34 T 28-03-2018 CU254_RS12965 949d6793524935fac041ad36a01931f5 73 SMART SM00923 3 53 8.1E-32 T 28-03-2018 IPR005153 MbtH-like protein CU254_RS12965 949d6793524935fac041ad36a01931f5 73 SUPERFAMILY SSF160582 1 70 2.62E-31 T 28-03-2018 CU254_RS07575 227c6a8999518678323775bdda1795c9 268 Pfam PF01614 Bacterial transcriptional regulator 129 255 1.5E-39 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal CU254_RS07575 227c6a8999518678323775bdda1795c9 268 TIGRFAM TIGR02431 pcaR_pcaU: beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family 12 256 4.5E-101 T 28-03-2018 IPR012794 Beta-ketoadipate transcriptional regulator, PcaR/PcaU/PobR GO:0003677|GO:0045893|GO:0046278 CU254_RS07575 227c6a8999518678323775bdda1795c9 268 Gene3D G3DSA:1.10.10.10 5 81 1.9E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS07575 227c6a8999518678323775bdda1795c9 268 SUPERFAMILY SSF46785 14 86 3.84E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS07575 227c6a8999518678323775bdda1795c9 268 SUPERFAMILY SSF55781 78 257 4.38E-48 T 28-03-2018 IPR029016 GAF domain-like CU254_RS07575 227c6a8999518678323775bdda1795c9 268 SMART SM00346 14 102 2.4E-36 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS07575 227c6a8999518678323775bdda1795c9 268 Gene3D G3DSA:3.30.450.40 82 267 1.9E-55 T 28-03-2018 IPR029016 GAF domain-like CU254_RS07575 227c6a8999518678323775bdda1795c9 268 Pfam PF09339 IclR helix-turn-helix domain 16 67 1.9E-15 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS24560 2929fe7100f34bce53c9d0c7669f156b 144 Gene3D G3DSA:3.30.300.20 6 143 3.7E-31 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CU254_RS24560 2929fe7100f34bce53c9d0c7669f156b 144 SUPERFAMILY SSF82784 6 135 2.49E-33 T 28-03-2018 IPR003718 OsmC/Ohr family CU254_RS24560 2929fe7100f34bce53c9d0c7669f156b 144 Pfam PF02566 OsmC-like protein 43 139 5.4E-19 T 28-03-2018 IPR003718 OsmC/Ohr family CU254_RS24560 2929fe7100f34bce53c9d0c7669f156b 144 TIGRFAM TIGR03562 osmo_induc_OsmC: peroxiredoxin, OsmC subfamily 4 141 3.4E-45 T 28-03-2018 IPR019904 Peroxiredoxin OsmC GO:0004601|GO:0006979 KEGG: 00480+1.11.1.15 CU254_RS10700 82fae4da72474e2b8bceb496b93a4f85 114 Pfam PF11298 Protein of unknown function (DUF3099) 22 90 1.6E-31 T 28-03-2018 IPR021449 Protein of unknown function DUF3099 CU254_RS32300 2e425ddc423f61e5e9bd5e0d48c396a2 158 Gene3D G3DSA:3.10.129.10 10 155 2.1E-18 T 28-03-2018 CU254_RS32300 2e425ddc423f61e5e9bd5e0d48c396a2 158 Pfam PF14539 Domain of unknown function (DUF4442) 19 152 1.6E-57 T 28-03-2018 IPR027961 Protein of unknown function DUF4442 CU254_RS32300 2e425ddc423f61e5e9bd5e0d48c396a2 158 SUPERFAMILY SSF54637 17 154 5.39E-21 T 28-03-2018 IPR029069 HotDog domain CU254_RS19025 58ee01f7c6eb0250be8f87842bfc16f6 154 Gene3D G3DSA:3.30.530.20 1 153 1.1E-24 T 28-03-2018 IPR023393 START-like domain CU254_RS19025 58ee01f7c6eb0250be8f87842bfc16f6 154 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 9 150 3.4E-13 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase CU254_RS19025 58ee01f7c6eb0250be8f87842bfc16f6 154 SUPERFAMILY SSF55961 8 150 4.13E-22 T 28-03-2018 CU254_RS21255 68712f3b55b0a07f77ed26cbe1f00343 684 Gene3D G3DSA:1.10.287.1060 128 221 6.5E-7 T 28-03-2018 CU254_RS21255 68712f3b55b0a07f77ed26cbe1f00343 684 SUPERFAMILY SSF140459 116 287 2.33E-6 T 28-03-2018 CU254_RS33415 c46c66c20dcef7b2abe296ec00980a74 295 SUPERFAMILY SSF56281 55 283 1.83E-29 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS33415 c46c66c20dcef7b2abe296ec00980a74 295 SMART SM00849 56 261 7.1E-14 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS33415 c46c66c20dcef7b2abe296ec00980a74 295 Pfam PF00753 Metallo-beta-lactamase superfamily 57 244 1.6E-16 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS33415 c46c66c20dcef7b2abe296ec00980a74 295 Gene3D G3DSA:3.60.15.10 2 284 6.4E-36 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS29605 96e45426c0fe43dacf2a7e69992b3e52 391 Pfam PF13458 Periplasmic binding protein 30 365 2.3E-48 T 28-03-2018 IPR028081 Leucine-binding protein domain CU254_RS29605 96e45426c0fe43dacf2a7e69992b3e52 391 Gene3D G3DSA:3.40.50.2300 24 141 1.9E-18 T 28-03-2018 CU254_RS29605 96e45426c0fe43dacf2a7e69992b3e52 391 SUPERFAMILY SSF53822 30 359 2.77E-46 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CU254_RS29605 96e45426c0fe43dacf2a7e69992b3e52 391 Gene3D G3DSA:3.40.50.2300 171 363 2.1E-16 T 28-03-2018 CU254_RS02040 3e79b61fb3b8f06e3f81cf9ef594cd37 61 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 4 58 1.7E-23 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS02040 3e79b61fb3b8f06e3f81cf9ef594cd37 61 ProSitePatterns PS00634 Ribosomal protein L30 signature. 22 54 - T 28-03-2018 IPR018038 Ribosomal protein L30, conserved site CU254_RS02040 3e79b61fb3b8f06e3f81cf9ef594cd37 61 Pfam PF00327 Ribosomal protein L30p/L7e 4 54 1.1E-17 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CU254_RS02040 3e79b61fb3b8f06e3f81cf9ef594cd37 61 Gene3D G3DSA:3.30.1390.20 4 58 5.0E-23 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CU254_RS02040 3e79b61fb3b8f06e3f81cf9ef594cd37 61 PIRSF PIRSF002211 1 60 1.0E-27 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS02040 3e79b61fb3b8f06e3f81cf9ef594cd37 61 SUPERFAMILY SSF55129 1 59 6.41E-21 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CU254_RS02040 3e79b61fb3b8f06e3f81cf9ef594cd37 61 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 1 58 20.456 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS13975 defc56fb86919e2dfd7e75511973e03a 301 Gene3D G3DSA:3.40.190.10 179 266 1.9E-20 T 28-03-2018 CU254_RS13975 defc56fb86919e2dfd7e75511973e03a 301 Pfam PF03466 LysR substrate binding domain 87 292 7.5E-39 T 28-03-2018 IPR005119 LysR, substrate-binding CU254_RS13975 defc56fb86919e2dfd7e75511973e03a 301 SUPERFAMILY SSF53850 88 296 4.96E-38 T 28-03-2018 CU254_RS13975 defc56fb86919e2dfd7e75511973e03a 301 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 7.6E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS13975 defc56fb86919e2dfd7e75511973e03a 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 7.3E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS13975 defc56fb86919e2dfd7e75511973e03a 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 7.3E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS13975 defc56fb86919e2dfd7e75511973e03a 301 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 7.3E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS13975 defc56fb86919e2dfd7e75511973e03a 301 Gene3D G3DSA:1.10.10.10 1 78 2.2E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS13975 defc56fb86919e2dfd7e75511973e03a 301 SUPERFAMILY SSF46785 1 86 1.03E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS13975 defc56fb86919e2dfd7e75511973e03a 301 Gene3D G3DSA:3.40.190.10 79 178 8.8E-21 T 28-03-2018 CU254_RS24285 4c8100c2a300bf7a257d6c4737efb7c3 214 Gene3D G3DSA:1.10.10.60 2 66 1.1E-23 T 28-03-2018 CU254_RS24285 4c8100c2a300bf7a257d6c4737efb7c3 214 SUPERFAMILY SSF46689 4 78 4.19E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS24285 4c8100c2a300bf7a257d6c4737efb7c3 214 Gene3D G3DSA:1.10.357.10 67 190 2.9E-15 T 28-03-2018 CU254_RS24285 4c8100c2a300bf7a257d6c4737efb7c3 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 1.8E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS24285 4c8100c2a300bf7a257d6c4737efb7c3 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 1.8E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS24285 4c8100c2a300bf7a257d6c4737efb7c3 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 61 2.6E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS38625 23dfac2d3a1a1e3b1601ae67be00fd12 214 Pfam PF02036 SCP-2 sterol transfer family 117 206 6.0E-12 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CU254_RS38625 23dfac2d3a1a1e3b1601ae67be00fd12 214 SUPERFAMILY SSF55718 106 212 8.95E-18 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CU254_RS38625 23dfac2d3a1a1e3b1601ae67be00fd12 214 Gene3D G3DSA:3.30.1050.10 101 210 2.7E-17 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CU254_RS06255 18121a6fa207b0012a61a3569559c61f 526 SUPERFAMILY SSF52058 384 493 5.67E-8 T 28-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like CU254_RS06255 18121a6fa207b0012a61a3569559c61f 526 Pfam PF09346 SMI1 / KNR4 family (SUKH-1) 158 297 2.7E-9 T 28-03-2018 IPR018958 Knr4/Smi1-like domain CU254_RS06255 18121a6fa207b0012a61a3569559c61f 526 SUPERFAMILY SSF160631 137 302 7.72E-10 T 28-03-2018 CU254_RS06255 18121a6fa207b0012a61a3569559c61f 526 Gene3D G3DSA:3.40.1580.10 136 303 3.8E-17 T 28-03-2018 CU254_RS06255 18121a6fa207b0012a61a3569559c61f 526 Gene3D G3DSA:3.80.10.10 320 518 8.5E-12 T 28-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like CU254_RS06255 18121a6fa207b0012a61a3569559c61f 526 SMART SM00860 156 298 5.1E-6 T 28-03-2018 IPR018958 Knr4/Smi1-like domain CU254_RS36400 d4ad3113974b3cb7399f2ced04d87b9d 172 Gene3D G3DSA:2.160.10.10 3 172 1.8E-40 T 28-03-2018 CU254_RS36400 d4ad3113974b3cb7399f2ced04d87b9d 172 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 87 121 6.8E-7 T 28-03-2018 IPR001451 Hexapeptide repeat CU254_RS36400 d4ad3113974b3cb7399f2ced04d87b9d 172 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 10 44 1.6E-5 T 28-03-2018 IPR001451 Hexapeptide repeat CU254_RS36400 d4ad3113974b3cb7399f2ced04d87b9d 172 SUPERFAMILY SSF51161 2 166 1.22E-43 T 28-03-2018 IPR011004 Trimeric LpxA-like CU254_RS15090 10a108fb372072201a3588148f29124b 238 SUPERFAMILY SSF53335 36 223 1.19E-35 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS15090 10a108fb372072201a3588148f29124b 238 Pfam PF13649 Methyltransferase domain 78 167 1.0E-18 T 28-03-2018 CU254_RS15090 10a108fb372072201a3588148f29124b 238 Gene3D G3DSA:3.40.50.150 33 236 5.1E-36 T 28-03-2018 CU254_RS09490 098d87d718944e6d82c0c11ea0a080f3 195 Gene3D G3DSA:3.40.630.30 15 188 2.8E-18 T 28-03-2018 CU254_RS09490 098d87d718944e6d82c0c11ea0a080f3 195 Pfam PF00583 Acetyltransferase (GNAT) family 33 163 9.9E-6 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS09490 098d87d718944e6d82c0c11ea0a080f3 195 SUPERFAMILY SSF55729 26 179 3.6E-14 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS08740 e5d50891749d3355c2eeb7e347a5abf1 209 Pfam PF01569 PAP2 superfamily 88 190 1.2E-7 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CU254_RS08740 e5d50891749d3355c2eeb7e347a5abf1 209 SMART SM00014 84 191 0.0051 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CU254_RS08740 e5d50891749d3355c2eeb7e347a5abf1 209 Gene3D G3DSA:1.20.144.10 24 197 7.6E-17 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CU254_RS08740 e5d50891749d3355c2eeb7e347a5abf1 209 SUPERFAMILY SSF48317 5 199 2.22E-23 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CU254_RS02330 9eb2bfc6894ad8439b1bf1cfb70efbef 160 SUPERFAMILY SSF55729 5 138 8.1E-30 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS02330 9eb2bfc6894ad8439b1bf1cfb70efbef 160 Pfam PF00583 Acetyltransferase (GNAT) family 25 126 1.9E-16 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS02330 9eb2bfc6894ad8439b1bf1cfb70efbef 160 Gene3D G3DSA:3.40.630.30 1 159 2.8E-33 T 28-03-2018 CU254_RS02330 9eb2bfc6894ad8439b1bf1cfb70efbef 160 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 10 146 2.0E-33 T 28-03-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 CU254_RS07085 398e8c65d2a8fe6bf412d4bfe2e205c0 483 Pfam PF00512 His Kinase A (phospho-acceptor) domain 260 325 1.5E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS07085 398e8c65d2a8fe6bf412d4bfe2e205c0 483 SMART SM00387 372 483 8.0E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS07085 398e8c65d2a8fe6bf412d4bfe2e205c0 483 SMART SM00388 259 326 4.1E-20 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS07085 398e8c65d2a8fe6bf412d4bfe2e205c0 483 Gene3D G3DSA:3.30.565.10 332 483 2.4E-39 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS07085 398e8c65d2a8fe6bf412d4bfe2e205c0 483 SMART SM00304 192 251 1.7E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS07085 398e8c65d2a8fe6bf412d4bfe2e205c0 483 PRINTS PR00344 Bacterial sensor protein C-terminal signature 409 423 7.2E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS07085 398e8c65d2a8fe6bf412d4bfe2e205c0 483 PRINTS PR00344 Bacterial sensor protein C-terminal signature 427 437 7.2E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS07085 398e8c65d2a8fe6bf412d4bfe2e205c0 483 PRINTS PR00344 Bacterial sensor protein C-terminal signature 467 480 7.2E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS07085 398e8c65d2a8fe6bf412d4bfe2e205c0 483 PRINTS PR00344 Bacterial sensor protein C-terminal signature 444 462 7.2E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS07085 398e8c65d2a8fe6bf412d4bfe2e205c0 483 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 373 482 1.5E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS07085 398e8c65d2a8fe6bf412d4bfe2e205c0 483 SUPERFAMILY SSF47384 247 326 4.32E-19 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS07085 398e8c65d2a8fe6bf412d4bfe2e205c0 483 SUPERFAMILY SSF55874 315 481 7.6E-40 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS07085 398e8c65d2a8fe6bf412d4bfe2e205c0 483 Gene3D G3DSA:1.10.287.130 265 322 9.2E-18 T 28-03-2018 CU254_RS07085 398e8c65d2a8fe6bf412d4bfe2e205c0 483 Gene3D G3DSA:3.30.450.20 45 264 7.9E-4 T 28-03-2018 CU254_RS33895 bd71acceb262f7c74cb3ff3d2e976302 279 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 7 210 1.5E-29 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CU254_RS33895 bd71acceb262f7c74cb3ff3d2e976302 279 SUPERFAMILY SSF53790 6 225 1.57E-70 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CU254_RS33895 bd71acceb262f7c74cb3ff3d2e976302 279 Gene3D G3DSA:3.30.950.10 119 235 1.9E-41 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CU254_RS33895 bd71acceb262f7c74cb3ff3d2e976302 279 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 8 275 8.7E-58 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CU254_RS33895 bd71acceb262f7c74cb3ff3d2e976302 279 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 7 227 32.535 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CU254_RS33895 bd71acceb262f7c74cb3ff3d2e976302 279 Gene3D G3DSA:3.40.1010.10 5 118 2.2E-30 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CU254_RS33895 bd71acceb262f7c74cb3ff3d2e976302 279 PIRSF PIRSF005917 1 279 8.2E-88 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CU254_RS04370 d11fc541419cfffe6ec78a6ab3a59929 247 SMART SM00345 26 87 2.4E-12 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS04370 d11fc541419cfffe6ec78a6ab3a59929 247 Pfam PF00392 Bacterial regulatory proteins, gntR family 23 82 8.9E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS04370 d11fc541419cfffe6ec78a6ab3a59929 247 SUPERFAMILY SSF48008 109 239 1.46E-18 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS04370 d11fc541419cfffe6ec78a6ab3a59929 247 Pfam PF07729 FCD domain 119 230 9.7E-21 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS04370 d11fc541419cfffe6ec78a6ab3a59929 247 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 59 5.7E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS04370 d11fc541419cfffe6ec78a6ab3a59929 247 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 59 75 5.7E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS04370 d11fc541419cfffe6ec78a6ab3a59929 247 SMART SM00895 112 232 3.0E-10 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS04370 d11fc541419cfffe6ec78a6ab3a59929 247 Gene3D G3DSA:1.10.10.10 1 89 3.7E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS04370 d11fc541419cfffe6ec78a6ab3a59929 247 SUPERFAMILY SSF46785 14 91 8.56E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS04370 d11fc541419cfffe6ec78a6ab3a59929 247 Gene3D G3DSA:1.20.120.530 95 246 3.5E-22 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS02465 289ab971968e2ea87a39906b9f9e9db6 481 SUPERFAMILY SSF53720 8 476 1.44E-133 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CU254_RS02465 289ab971968e2ea87a39906b9f9e9db6 481 Gene3D G3DSA:3.40.309.10 268 460 4.9E-58 T 28-03-2018 CU254_RS02465 289ab971968e2ea87a39906b9f9e9db6 481 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 251 258 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CU254_RS02465 289ab971968e2ea87a39906b9f9e9db6 481 Pfam PF00171 Aldehyde dehydrogenase family 20 471 4.0E-134 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CU254_RS02465 289ab971968e2ea87a39906b9f9e9db6 481 Gene3D G3DSA:3.40.605.10 2 267 2.7E-73 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CU254_RS06260 176435c11f834e431520c111200dc8a3 196 SUPERFAMILY SSF46689 6 76 1.04E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS06260 176435c11f834e431520c111200dc8a3 196 SUPERFAMILY SSF48498 85 195 4.45E-20 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS06260 176435c11f834e431520c111200dc8a3 196 Gene3D G3DSA:1.10.357.10 64 196 4.2E-24 T 28-03-2018 CU254_RS06260 176435c11f834e431520c111200dc8a3 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 61 1.6E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS06260 176435c11f834e431520c111200dc8a3 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 5.1E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS06260 176435c11f834e431520c111200dc8a3 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 5.1E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS06260 176435c11f834e431520c111200dc8a3 196 Gene3D G3DSA:1.10.10.60 1 61 5.2E-18 T 28-03-2018 CU254_RS30325 fc3d11bfaf26d5f477b474024dc3ca94 179 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 18 170 5.0E-28 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS30325 fc3d11bfaf26d5f477b474024dc3ca94 179 Gene3D G3DSA:1.10.1740.10 5 82 1.4E-21 T 28-03-2018 CU254_RS30325 fc3d11bfaf26d5f477b474024dc3ca94 179 Gene3D G3DSA:1.10.10.10 83 178 3.5E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS30325 fc3d11bfaf26d5f477b474024dc3ca94 179 Pfam PF04545 Sigma-70, region 4 120 169 1.0E-13 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS30325 fc3d11bfaf26d5f477b474024dc3ca94 179 Pfam PF04542 Sigma-70 region 2 21 87 8.3E-20 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS30325 fc3d11bfaf26d5f477b474024dc3ca94 179 SUPERFAMILY SSF88946 13 94 1.77E-20 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS30325 fc3d11bfaf26d5f477b474024dc3ca94 179 SUPERFAMILY SSF88659 107 171 6.54E-15 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS09550 2bf2915599d42f23c306067548023aed 347 ProSitePatterns PS00321 recA signature. 215 223 - T 28-03-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 CU254_RS09550 2bf2915599d42f23c306067548023aed 347 SUPERFAMILY SSF54752 270 328 5.1E-21 T 28-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal CU254_RS09550 2bf2915599d42f23c306067548023aed 347 Pfam PF00154 recA bacterial DNA recombination protein 9 270 5.3E-142 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CU254_RS09550 2bf2915599d42f23c306067548023aed 347 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 6 326 6.5E-173 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CU254_RS09550 2bf2915599d42f23c306067548023aed 347 SUPERFAMILY SSF52540 6 268 5.93E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS09550 2bf2915599d42f23c306067548023aed 347 Hamap MF_00268 Protein RecA [recA]. 7 331 52.617 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CU254_RS09550 2bf2915599d42f23c306067548023aed 347 Gene3D G3DSA:3.30.250.10 271 328 2.1E-26 T 28-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal CU254_RS09550 2bf2915599d42f23c306067548023aed 347 Gene3D G3DSA:3.40.50.300 28 270 1.0E-48 T 28-03-2018 CU254_RS09550 2bf2915599d42f23c306067548023aed 347 SMART SM00382 59 230 1.9E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS09550 2bf2915599d42f23c306067548023aed 347 PRINTS PR00142 RecA protein signature 245 274 1.5E-85 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CU254_RS09550 2bf2915599d42f23c306067548023aed 347 PRINTS PR00142 RecA protein signature 95 124 1.5E-85 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CU254_RS09550 2bf2915599d42f23c306067548023aed 347 PRINTS PR00142 RecA protein signature 212 240 1.5E-85 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CU254_RS09550 2bf2915599d42f23c306067548023aed 347 PRINTS PR00142 RecA protein signature 129 158 1.5E-85 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CU254_RS09550 2bf2915599d42f23c306067548023aed 347 PRINTS PR00142 RecA protein signature 167 196 1.5E-85 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CU254_RS09550 2bf2915599d42f23c306067548023aed 347 PRINTS PR00142 RecA protein signature 299 316 1.5E-85 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CU254_RS03880 7058898b88993fdac4a2600a03a18d73 217 SUPERFAMILY SSF56300 16 206 6.73E-28 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CU254_RS03880 7058898b88993fdac4a2600a03a18d73 217 Gene3D G3DSA:3.60.21.10 9 212 6.1E-21 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CU254_RS03880 7058898b88993fdac4a2600a03a18d73 217 Pfam PF00149 Calcineurin-like phosphoesterase 22 189 3.7E-10 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CU254_RS20675 bae1bb4d1fe4bea2bc9c3561ce155665 173 Gene3D G3DSA:3.10.450.50 6 161 1.9E-35 T 28-03-2018 CU254_RS20675 bae1bb4d1fe4bea2bc9c3561ce155665 173 Pfam PF13577 SnoaL-like domain 10 138 2.0E-30 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CU254_RS20675 bae1bb4d1fe4bea2bc9c3561ce155665 173 SUPERFAMILY SSF54427 8 155 1.81E-36 T 28-03-2018 IPR032710 NTF2-like domain CU254_RS12455 30376ea39de387e54e359bb00dfd8b12 397 Gene3D G3DSA:3.40.630.30 130 280 7.4E-49 T 28-03-2018 CU254_RS12455 30376ea39de387e54e359bb00dfd8b12 397 Pfam PF13530 Sterol carrier protein domain 179 393 4.0E-49 T 28-03-2018 IPR025559 Enhanced intracellular survival protein domain CU254_RS12455 30376ea39de387e54e359bb00dfd8b12 397 Gene3D G3DSA:3.30.1050.10 281 390 1.1E-28 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CU254_RS12455 30376ea39de387e54e359bb00dfd8b12 397 SUPERFAMILY SSF55729 6 292 7.54E-58 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS12455 30376ea39de387e54e359bb00dfd8b12 397 Pfam PF13527 Acetyltransferase (GNAT) domain 8 126 2.2E-21 T 28-03-2018 CU254_RS12455 30376ea39de387e54e359bb00dfd8b12 397 Hamap MF_01812 UPF0256 protein . 10 397 30.491 T 28-03-2018 IPR022902 N-acetyltransferase Eis CU254_RS12455 30376ea39de387e54e359bb00dfd8b12 397 Gene3D G3DSA:3.40.630.30 2 129 9.9E-11 T 28-03-2018 CU254_RS12455 30376ea39de387e54e359bb00dfd8b12 397 SUPERFAMILY SSF55718 293 397 9.03E-25 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CU254_RS23795 d4ffdcbac45adccccaecf6b47f945c3d 321 Gene3D G3DSA:3.20.20.30 9 197 5.7E-37 T 28-03-2018 CU254_RS23795 d4ffdcbac45adccccaecf6b47f945c3d 321 Gene3D G3DSA:3.20.20.30 198 321 5.7E-8 T 28-03-2018 CU254_RS23795 d4ffdcbac45adccccaecf6b47f945c3d 321 SUPERFAMILY SSF51679 14 309 4.86E-51 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS23795 d4ffdcbac45adccccaecf6b47f945c3d 321 Pfam PF00296 Luciferase-like monooxygenase 19 197 6.1E-28 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS12905 e26ada1b1e8b23a4ecf0968562de6588 455 Pfam PF07690 Major Facilitator Superfamily 17 408 1.3E-42 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS12905 e26ada1b1e8b23a4ecf0968562de6588 455 ProSitePatterns PS00216 Sugar transport proteins signature 1. 64 81 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CU254_RS12905 e26ada1b1e8b23a4ecf0968562de6588 455 SUPERFAMILY SSF103473 245 446 1.57E-51 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS12905 e26ada1b1e8b23a4ecf0968562de6588 455 SUPERFAMILY SSF103473 3 197 1.57E-51 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS12905 e26ada1b1e8b23a4ecf0968562de6588 455 Gene3D G3DSA:1.20.1250.20 2 199 1.0E-29 T 28-03-2018 CU254_RS12905 e26ada1b1e8b23a4ecf0968562de6588 455 Gene3D G3DSA:1.20.1250.20 249 455 7.9E-17 T 28-03-2018 CU254_RS35610 05d3aa4d57cbc6d3f7f2a21ac534d391 300 SUPERFAMILY SSF51197 37 297 1.37E-57 T 28-03-2018 CU254_RS35610 05d3aa4d57cbc6d3f7f2a21ac534d391 300 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 49 262 2.5E-33 T 28-03-2018 IPR008775 Phytanoyl-CoA dioxygenase CU254_RS35610 05d3aa4d57cbc6d3f7f2a21ac534d391 300 Gene3D G3DSA:2.60.120.620 26 286 4.9E-40 T 28-03-2018 CU254_RS35610 05d3aa4d57cbc6d3f7f2a21ac534d391 300 TIGRFAM TIGR02408 ectoine_ThpD: ectoine hydroxylase 24 298 3.3E-129 T 28-03-2018 IPR012774 Ectoine dioxygenase GO:0016706|GO:0055114 CU254_RS11550 e5e69c1b827099911ed96626f440d981 220 SUPERFAMILY SSF51206 4 137 3.8E-28 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like CU254_RS11550 e5e69c1b827099911ed96626f440d981 220 SUPERFAMILY SSF46785 142 219 1.46E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS11550 e5e69c1b827099911ed96626f440d981 220 Gene3D G3DSA:2.60.120.10 1 133 3.9E-23 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS11550 e5e69c1b827099911ed96626f440d981 220 Gene3D G3DSA:1.10.10.10 134 219 3.4E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS11550 e5e69c1b827099911ed96626f440d981 220 Pfam PF00027 Cyclic nucleotide-binding domain 25 111 2.4E-20 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CU254_RS11550 e5e69c1b827099911ed96626f440d981 220 SMART SM00100 6 124 3.4E-13 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CU254_RS11550 e5e69c1b827099911ed96626f440d981 220 Pfam PF13545 Crp-like helix-turn-helix domain 145 218 3.9E-12 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CU254_RS11550 e5e69c1b827099911ed96626f440d981 220 ProSitePatterns PS00888 Cyclic nucleotide-binding domain signature 1. 33 49 - T 28-03-2018 IPR018488 Cyclic nucleotide-binding, conserved site CU254_RS11550 e5e69c1b827099911ed96626f440d981 220 ProSitePatterns PS00889 Cyclic nucleotide-binding domain signature 2. 74 91 - T 28-03-2018 IPR018488 Cyclic nucleotide-binding, conserved site CU254_RS08420 88ee716f52b3407599160dff04dd37d9 575 Pfam PF00271 Helicase conserved C-terminal domain 280 377 2.0E-23 T 28-03-2018 IPR001650 Helicase, C-terminal CU254_RS08420 88ee716f52b3407599160dff04dd37d9 575 SMART SM00490 296 377 1.5E-28 T 28-03-2018 IPR001650 Helicase, C-terminal CU254_RS08420 88ee716f52b3407599160dff04dd37d9 575 Gene3D G3DSA:3.40.50.300 267 552 2.6E-41 T 28-03-2018 CU254_RS08420 88ee716f52b3407599160dff04dd37d9 575 SUPERFAMILY SSF52540 32 248 2.86E-66 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS08420 88ee716f52b3407599160dff04dd37d9 575 Pfam PF00270 DEAD/DEAH box helicase 67 236 1.8E-42 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CU254_RS08420 88ee716f52b3407599160dff04dd37d9 575 SUPERFAMILY SSF52540 295 411 1.05E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS08420 88ee716f52b3407599160dff04dd37d9 575 SUPERFAMILY SSF52540 80 139 1.05E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS08420 88ee716f52b3407599160dff04dd37d9 575 Gene3D G3DSA:3.40.50.300 12 266 2.1E-55 T 28-03-2018 CU254_RS08420 88ee716f52b3407599160dff04dd37d9 575 SMART SM00487 62 262 9.6E-55 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CU254_RS06270 a99ace87a4aa80e5640115bb00f8ddc1 131 Pfam PF03061 Thioesterase superfamily 39 108 1.2E-8 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CU254_RS06270 a99ace87a4aa80e5640115bb00f8ddc1 131 SUPERFAMILY SSF54637 2 119 1.53E-24 T 28-03-2018 IPR029069 HotDog domain CU254_RS06270 a99ace87a4aa80e5640115bb00f8ddc1 131 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 9 106 4.8E-17 T 28-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 CU254_RS06270 a99ace87a4aa80e5640115bb00f8ddc1 131 TIGRFAM TIGR02286 PaaD: phenylacetic acid degradation protein PaaD 9 123 6.4E-41 T 28-03-2018 IPR011973 Phenylacetic acid degradation protein PaaD GO:0016790 CU254_RS06270 a99ace87a4aa80e5640115bb00f8ddc1 131 Gene3D G3DSA:3.10.129.10 1 127 6.9E-26 T 28-03-2018 CU254_RS35640 0449f46edf2637b28aeea94210ee40ea 263 Pfam PF14337 Domain of unknown function (DUF4393) 108 258 9.1E-15 T 28-03-2018 IPR025506 Protein of unknown function DUF4393 CU254_RS35640 0449f46edf2637b28aeea94210ee40ea 263 Gene3D G3DSA:1.10.10.10 124 249 0.0017 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS04795 778bee0f370f6ff93df4bae8d8656079 358 Gene3D G3DSA:3.40.50.720 124 357 2.4E-22 T 28-03-2018 CU254_RS04795 778bee0f370f6ff93df4bae8d8656079 358 Pfam PF00899 ThiF family 120 337 1.2E-10 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CU254_RS04795 778bee0f370f6ff93df4bae8d8656079 358 SUPERFAMILY SSF69572 108 336 2.35E-11 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CU254_RS11590 a35821c4d0ec760bf094fb2a2093e3f5 227 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 36 50 - T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CU254_RS11590 a35821c4d0ec760bf094fb2a2093e3f5 227 Pfam PF00834 Ribulose-phosphate 3 epimerase family 6 205 2.7E-75 T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CU254_RS11590 a35821c4d0ec760bf094fb2a2093e3f5 227 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 138 160 - T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CU254_RS11590 a35821c4d0ec760bf094fb2a2093e3f5 227 PIRSF PIRSF001461 1 227 1.8E-88 T 28-03-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CU254_RS11590 a35821c4d0ec760bf094fb2a2093e3f5 227 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 5 218 3.4E-79 T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CU254_RS11590 a35821c4d0ec760bf094fb2a2093e3f5 227 Gene3D G3DSA:3.20.20.70 1 222 4.0E-82 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS11590 a35821c4d0ec760bf094fb2a2093e3f5 227 SUPERFAMILY SSF51366 5 220 1.6E-63 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CU254_RS11130 8959fde0d639d5d6846b578e8243bb3b 545 Gene3D G3DSA:3.30.200.20 1 93 2.3E-21 T 28-03-2018 CU254_RS11130 8959fde0d639d5d6846b578e8243bb3b 545 Pfam PF00069 Protein kinase domain 6 258 1.1E-46 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CU254_RS11130 8959fde0d639d5d6846b578e8243bb3b 545 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 12 35 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 CU254_RS11130 8959fde0d639d5d6846b578e8243bb3b 545 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 129 141 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CU254_RS11130 8959fde0d639d5d6846b578e8243bb3b 545 SUPERFAMILY SSF56112 2 331 1.62E-67 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS11130 8959fde0d639d5d6846b578e8243bb3b 545 SMART SM00220 6 264 1.2E-54 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CU254_RS11130 8959fde0d639d5d6846b578e8243bb3b 545 Gene3D G3DSA:1.10.510.10 94 309 6.0E-46 T 28-03-2018 CU254_RS01565 90055b3f8d99da779bbc6056e58aa95c 364 Pfam PF08484 C-methyltransferase C-terminal domain 207 356 1.5E-29 T 28-03-2018 IPR013691 C-methyltransferase CU254_RS01565 90055b3f8d99da779bbc6056e58aa95c 364 Gene3D G3DSA:3.40.50.150 6 216 2.4E-7 T 28-03-2018 CU254_RS01565 90055b3f8d99da779bbc6056e58aa95c 364 SUPERFAMILY SSF53335 117 211 4.25E-7 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS01565 90055b3f8d99da779bbc6056e58aa95c 364 Pfam PF08421 Putative zinc binding domain 6 58 1.1E-11 T 28-03-2018 IPR013630 Methyltransferase putative zinc binding domain CU254_RS02675 ec177c89a88aad51d4c7857a2ea413ca 392 Gene3D G3DSA:1.20.1250.20 3 187 4.6E-28 T 28-03-2018 CU254_RS02675 ec177c89a88aad51d4c7857a2ea413ca 392 Pfam PF07690 Major Facilitator Superfamily 8 342 2.3E-43 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS02675 ec177c89a88aad51d4c7857a2ea413ca 392 SUPERFAMILY SSF103473 3 375 1.96E-57 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS02675 ec177c89a88aad51d4c7857a2ea413ca 392 Gene3D G3DSA:1.20.1250.20 191 389 3.5E-18 T 28-03-2018 CU254_RS20610 62d07817489b625846f370f53e4a89e7 144 Gene3D G3DSA:2.140.10.10 5 143 6.9E-17 T 28-03-2018 CU254_RS20610 62d07817489b625846f370f53e4a89e7 144 SUPERFAMILY SSF50998 18 131 3.92E-12 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CU254_RS20610 62d07817489b625846f370f53e4a89e7 144 Pfam PF13360 PQQ-like domain 26 116 4.6E-11 T 28-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat CU254_RS33720 aa6cdac51ddc0e6a061cdbe3349e9424 177 PRINTS PR00598 Bacterial regulatory protein MarR family signature 81 97 2.2E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS33720 aa6cdac51ddc0e6a061cdbe3349e9424 177 PRINTS PR00598 Bacterial regulatory protein MarR family signature 117 133 2.2E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS33720 aa6cdac51ddc0e6a061cdbe3349e9424 177 PRINTS PR00598 Bacterial regulatory protein MarR family signature 147 167 2.2E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS33720 aa6cdac51ddc0e6a061cdbe3349e9424 177 PRINTS PR00598 Bacterial regulatory protein MarR family signature 98 113 2.2E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS33720 aa6cdac51ddc0e6a061cdbe3349e9424 177 SUPERFAMILY SSF46785 28 172 2.38E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS33720 aa6cdac51ddc0e6a061cdbe3349e9424 177 Gene3D G3DSA:1.10.10.10 9 175 3.5E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS33720 aa6cdac51ddc0e6a061cdbe3349e9424 177 SMART SM00347 54 157 4.3E-14 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS33720 aa6cdac51ddc0e6a061cdbe3349e9424 177 Pfam PF12802 MarR family 59 121 5.6E-13 T 28-03-2018 CU254_RS04520 5c12ea2e50d8990245744a3c35865982 142 SUPERFAMILY SSF54637 6 130 2.7E-26 T 28-03-2018 IPR029069 HotDog domain CU254_RS04520 5c12ea2e50d8990245744a3c35865982 142 Pfam PF13279 Thioesterase-like superfamily 13 122 1.9E-11 T 28-03-2018 CU254_RS04520 5c12ea2e50d8990245744a3c35865982 142 Gene3D G3DSA:3.10.129.10 1 131 4.7E-22 T 28-03-2018 CU254_RS00160 5965ed49eb1739e89bd9742812d67af9 794 SUPERFAMILY SSF158745 459 780 2.62E-15 T 28-03-2018 CU254_RS00160 5965ed49eb1739e89bd9742812d67af9 794 SMART SM01260 465 786 0.0081 T 28-03-2018 IPR007822 Lanthionine synthetase C-like CU254_RS00160 5965ed49eb1739e89bd9742812d67af9 794 Gene3D G3DSA:3.30.2430.10 18 172 7.4E-15 T 28-03-2018 CU254_RS00160 5965ed49eb1739e89bd9742812d67af9 794 Gene3D G3DSA:1.50.10.10 404 755 3.3E-5 T 28-03-2018 CU254_RS00160 5965ed49eb1739e89bd9742812d67af9 794 Gene3D G3DSA:1.10.510.10 255 403 0.0017 T 28-03-2018 CU254_RS00160 5965ed49eb1739e89bd9742812d67af9 794 SUPERFAMILY SSF56112 256 369 8.41E-7 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS39095 f5f3eec4dad526a1b2089963506b31f7 430 SUPERFAMILY SSF103473 45 420 9.02E-23 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS39095 f5f3eec4dad526a1b2089963506b31f7 430 Pfam PF05977 Transmembrane secretion effector 44 418 4.0E-10 T 28-03-2018 IPR010290 Transmembrane secretion effector CU254_RS39095 f5f3eec4dad526a1b2089963506b31f7 430 Gene3D G3DSA:1.20.1250.20 8 200 2.3E-6 T 28-03-2018 CU254_RS39095 f5f3eec4dad526a1b2089963506b31f7 430 Gene3D G3DSA:1.20.1250.20 221 429 3.7E-14 T 28-03-2018 CU254_RS19925 5569972030d9ab8136405c18f21bd625 307 Gene3D G3DSA:1.10.10.10 1 86 7.2E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS19925 5569972030d9ab8136405c18f21bd625 307 SUPERFAMILY SSF46785 1 111 6.82E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS19925 5569972030d9ab8136405c18f21bd625 307 Gene3D G3DSA:3.40.190.10 178 261 4.1E-20 T 28-03-2018 CU254_RS19925 5569972030d9ab8136405c18f21bd625 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.1E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS19925 5569972030d9ab8136405c18f21bd625 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.1E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS19925 5569972030d9ab8136405c18f21bd625 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.1E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS19925 5569972030d9ab8136405c18f21bd625 307 SUPERFAMILY SSF53850 90 292 3.37E-40 T 28-03-2018 CU254_RS19925 5569972030d9ab8136405c18f21bd625 307 Pfam PF03466 LysR substrate binding domain 89 288 2.0E-43 T 28-03-2018 IPR005119 LysR, substrate-binding CU254_RS19925 5569972030d9ab8136405c18f21bd625 307 Gene3D G3DSA:3.40.190.10 88 177 3.5E-23 T 28-03-2018 CU254_RS19925 5569972030d9ab8136405c18f21bd625 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 1.8E-21 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS34510 a01c791078cecd4fd91844bea82c1e39 131 SUPERFAMILY SSF54593 1 128 4.63E-36 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS34510 a01c791078cecd4fd91844bea82c1e39 131 PIRSF PIRSF021700 1 131 1.9E-33 T 28-03-2018 IPR009725 Predicted 3-demethylubiquinone-9 3-methyltransferase CU254_RS34510 a01c791078cecd4fd91844bea82c1e39 131 Gene3D G3DSA:3.10.180.10 1 131 4.3E-28 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS34510 a01c791078cecd4fd91844bea82c1e39 131 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 4 127 3.2E-30 T 28-03-2018 IPR028973 PhnB-like CU254_RS33860 959f3c69dd31f6b098d29e4af5843dbf 332 Pfam PF00005 ABC transporter 25 167 6.1E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS33860 959f3c69dd31f6b098d29e4af5843dbf 332 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS33860 959f3c69dd31f6b098d29e4af5843dbf 332 Gene3D G3DSA:3.40.50.300 1 287 2.9E-64 T 28-03-2018 CU254_RS33860 959f3c69dd31f6b098d29e4af5843dbf 332 SMART SM00382 33 217 2.8E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS33860 959f3c69dd31f6b098d29e4af5843dbf 332 Pfam PF13732 Domain of unknown function (DUF4162) 222 310 9.3E-10 T 28-03-2018 IPR025302 Domain of unknown function DUF4162 CU254_RS33860 959f3c69dd31f6b098d29e4af5843dbf 332 SUPERFAMILY SSF52540 18 230 6.43E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS28515 390ef961c23d3d4ef4a8103f3c6f9868 336 Gene3D G3DSA:3.30.360.10 136 336 1.9E-34 T 28-03-2018 CU254_RS28515 390ef961c23d3d4ef4a8103f3c6f9868 336 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 120 5.5E-26 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CU254_RS28515 390ef961c23d3d4ef4a8103f3c6f9868 336 SUPERFAMILY SSF51735 4 155 2.18E-55 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS28515 390ef961c23d3d4ef4a8103f3c6f9868 336 Gene3D G3DSA:3.40.50.720 2 135 1.1E-43 T 28-03-2018 CU254_RS28515 390ef961c23d3d4ef4a8103f3c6f9868 336 SUPERFAMILY SSF55347 128 305 3.92E-34 T 28-03-2018 CU254_RS06195 478a17e918e4f6c3677afc913ced8c8f 491 Gene3D G3DSA:3.50.50.60 4 159 1.1E-39 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS06195 478a17e918e4f6c3677afc913ced8c8f 491 Gene3D G3DSA:3.50.50.60 160 484 5.9E-66 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS06195 478a17e918e4f6c3677afc913ced8c8f 491 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 8 216 1.4E-18 T 28-03-2018 CU254_RS06195 478a17e918e4f6c3677afc913ced8c8f 491 SUPERFAMILY SSF51905 6 224 6.48E-61 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS06195 478a17e918e4f6c3677afc913ced8c8f 491 SUPERFAMILY SSF51905 291 406 6.48E-61 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS06195 478a17e918e4f6c3677afc913ced8c8f 491 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 2.8E-6 T 28-03-2018 CU254_RS06195 478a17e918e4f6c3677afc913ced8c8f 491 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 170 195 2.8E-6 T 28-03-2018 CU254_RS12765 00da84703671e386aa5bc02618b2fb81 167 SUPERFAMILY SSF54593 23 164 9.13E-33 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS12765 00da84703671e386aa5bc02618b2fb81 167 Gene3D G3DSA:3.10.180.10 5 167 5.4E-35 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS12765 00da84703671e386aa5bc02618b2fb81 167 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 25 161 1.2E-18 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CU254_RS04940 37f1727fc251270e1b9d3be02d571f62 381 TIGRFAM TIGR01224 hutI: imidazolonepropionase 23 378 2.2E-101 T 28-03-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CU254_RS04940 37f1727fc251270e1b9d3be02d571f62 381 SUPERFAMILY SSF51556 58 339 1.08E-68 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS04940 37f1727fc251270e1b9d3be02d571f62 381 Hamap MF_00372 Imidazolonepropionase [hutI]. 2 380 41.214 T 28-03-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CU254_RS04940 37f1727fc251270e1b9d3be02d571f62 381 SUPERFAMILY SSF51338 319 378 4.32E-13 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS04940 37f1727fc251270e1b9d3be02d571f62 381 Gene3D G3DSA:2.30.40.10 2 73 1.4E-20 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS04940 37f1727fc251270e1b9d3be02d571f62 381 Gene3D G3DSA:3.20.20.140 74 339 9.8E-52 T 28-03-2018 CU254_RS04940 37f1727fc251270e1b9d3be02d571f62 381 Pfam PF01979 Amidohydrolase family 56 361 1.8E-15 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CU254_RS04940 37f1727fc251270e1b9d3be02d571f62 381 SUPERFAMILY SSF51338 15 72 5.18E-9 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS39540 c5ec755a7630b0c33443a84a5e11bfd3 510 SUPERFAMILY SSF53756 137 324 1.32E-6 T 28-03-2018 CU254_RS31010 1c83636c3eb803fe0b729505236755e7 99 SUPERFAMILY SSF54736 21 96 4.45E-25 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CU254_RS31010 1c83636c3eb803fe0b729505236755e7 99 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 6 99 18.374 T 28-03-2018 IPR022935 ATP-dependent Clp protease adaptor protein ClpS CU254_RS31010 1c83636c3eb803fe0b729505236755e7 99 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 23 93 3.1E-23 T 28-03-2018 IPR003769 Adaptor protein ClpS, core GO:0030163 Reactome: R-HSA-983168 CU254_RS31010 1c83636c3eb803fe0b729505236755e7 99 Gene3D G3DSA:3.30.1390.10 24 95 7.6E-27 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CU254_RS33375 58496963cc324b203c003af70443e829 461 Gene3D G3DSA:3.40.710.10 2 351 1.0E-86 T 28-03-2018 CU254_RS33375 58496963cc324b203c003af70443e829 461 SUPERFAMILY SSF56601 7 349 3.71E-84 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CU254_RS33375 58496963cc324b203c003af70443e829 461 Pfam PF00144 Beta-lactamase 12 337 6.0E-70 T 28-03-2018 IPR001466 Beta-lactamase-related CU254_RS22365 c569631c5647524e13005f4a21fe272e 382 Pfam PF06889 Protein of unknown function (DUF1266) 187 375 1.3E-33 T 28-03-2018 IPR009677 Protein of unknown function DUF1266 CU254_RS08040 e36c1c1b2434e3fd7fefde7388d7122d 198 SUPERFAMILY SSF51261 47 181 8.37E-19 T 28-03-2018 IPR011055 Duplicated hybrid motif CU254_RS08040 e36c1c1b2434e3fd7fefde7388d7122d 198 Gene3D G3DSA:2.70.70.10 43 185 1.9E-23 T 28-03-2018 CU254_RS08040 e36c1c1b2434e3fd7fefde7388d7122d 198 Pfam PF01551 Peptidase family M23 85 179 2.8E-17 T 28-03-2018 IPR016047 Peptidase M23 CU254_RS36355 dcd7497d8221fb742b72f4124f0e99a6 184 Gene3D G3DSA:3.40.50.2020 1 183 3.5E-44 T 28-03-2018 CU254_RS36355 dcd7497d8221fb742b72f4124f0e99a6 184 SUPERFAMILY SSF53271 5 181 3.28E-53 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CU254_RS36355 dcd7497d8221fb742b72f4124f0e99a6 184 Pfam PF00156 Phosphoribosyl transferase domain 14 163 2.9E-23 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CU254_RS36355 dcd7497d8221fb742b72f4124f0e99a6 184 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 9 176 9.1E-67 T 28-03-2018 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 CU254_RS35250 60efeb2580acaf1299768981791f28f4 464 Gene3D G3DSA:3.40.50.10380 84 234 1.1E-37 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CU254_RS35250 60efeb2580acaf1299768981791f28f4 464 Pfam PF00390 Malic enzyme, N-terminal domain 93 225 6.3E-28 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CU254_RS35250 60efeb2580acaf1299768981791f28f4 464 Pfam PF03949 Malic enzyme, NAD binding domain 239 454 6.6E-21 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CU254_RS35250 60efeb2580acaf1299768981791f28f4 464 SUPERFAMILY SSF51735 237 458 5.2E-66 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS35250 60efeb2580acaf1299768981791f28f4 464 PRINTS PR00072 Malic enzyme signature 233 249 6.0E-7 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CU254_RS35250 60efeb2580acaf1299768981791f28f4 464 PRINTS PR00072 Malic enzyme signature 264 280 6.0E-7 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CU254_RS35250 60efeb2580acaf1299768981791f28f4 464 PRINTS PR00072 Malic enzyme signature 154 176 6.0E-7 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CU254_RS35250 60efeb2580acaf1299768981791f28f4 464 SMART SM00919 237 459 2.3E-99 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CU254_RS35250 60efeb2580acaf1299768981791f28f4 464 Gene3D G3DSA:3.40.50.720 235 464 9.2E-65 T 28-03-2018 CU254_RS35250 60efeb2580acaf1299768981791f28f4 464 PIRSF PIRSF000106 31 464 1.3E-75 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CU254_RS35250 60efeb2580acaf1299768981791f28f4 464 SMART SM01274 92 225 3.9E-81 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CU254_RS35250 60efeb2580acaf1299768981791f28f4 464 SUPERFAMILY SSF53223 86 235 6.91E-55 T 28-03-2018 CU254_RS32795 c468ee8f8c709e7fe2325962e91379bb 74 SUPERFAMILY SSF116842 5 66 1.01E-16 T 28-03-2018 CU254_RS32795 c468ee8f8c709e7fe2325962e91379bb 74 PIRSF PIRSF006488 2 74 4.6E-21 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CU254_RS32795 c468ee8f8c709e7fe2325962e91379bb 74 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 9 49 2.0E-10 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CU254_RS32795 c468ee8f8c709e7fe2325962e91379bb 74 Pfam PF02609 Exonuclease VII small subunit 11 61 4.0E-16 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CU254_RS32795 c468ee8f8c709e7fe2325962e91379bb 74 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 11 64 1.2E-19 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CU254_RS32795 c468ee8f8c709e7fe2325962e91379bb 74 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 10 70 13.525 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CU254_RS32795 c468ee8f8c709e7fe2325962e91379bb 74 Gene3D G3DSA:1.10.287.1040 9 73 6.3E-19 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CU254_RS07590 10ac88ed9bbc487d13e7d8e039753ca3 371 Gene3D G3DSA:1.10.10.10 63 150 0.0038 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS07590 10ac88ed9bbc487d13e7d8e039753ca3 371 SUPERFAMILY SSF53300 198 329 5.65E-14 T 28-03-2018 IPR002035 von Willebrand factor, type A CU254_RS07590 10ac88ed9bbc487d13e7d8e039753ca3 371 Pfam PF05762 VWA domain containing CoxE-like protein 145 361 2.6E-56 T 28-03-2018 IPR008912 Uncharacterised protein family CoxE-like CU254_RS07590 10ac88ed9bbc487d13e7d8e039753ca3 371 PIRSF PIRSF010256 4 371 1.8E-91 T 28-03-2018 IPR011195 Uncharacterised conserved protein UCP010256 CU254_RS07590 10ac88ed9bbc487d13e7d8e039753ca3 371 Gene3D G3DSA:3.40.50.410 169 341 7.8E-11 T 28-03-2018 IPR002035 von Willebrand factor, type A CU254_RS06205 1bd64a4fa0cf546814155289c46f56df 338 Pfam PF12833 Helix-turn-helix domain 258 336 3.6E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS06205 1bd64a4fa0cf546814155289c46f56df 338 Gene3D G3DSA:1.10.10.60 285 338 2.5E-12 T 28-03-2018 CU254_RS06205 1bd64a4fa0cf546814155289c46f56df 338 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 41 209 3.4E-30 T 28-03-2018 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal CU254_RS06205 1bd64a4fa0cf546814155289c46f56df 338 SUPERFAMILY SSF46689 287 336 2.56E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS06205 1bd64a4fa0cf546814155289c46f56df 338 Gene3D G3DSA:1.10.10.10 22 284 3.0E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS06205 1bd64a4fa0cf546814155289c46f56df 338 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 318 334 5.9E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CU254_RS06205 1bd64a4fa0cf546814155289c46f56df 338 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 303 318 5.9E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CU254_RS06205 1bd64a4fa0cf546814155289c46f56df 338 SMART SM00342 252 334 6.9E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS13740 615f938f5fdcb6a028a291fa07f923dc 278 Pfam PF13460 NAD(P)H-binding 7 176 7.1E-18 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS13740 615f938f5fdcb6a028a291fa07f923dc 278 SUPERFAMILY SSF51735 2 240 3.29E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS13740 615f938f5fdcb6a028a291fa07f923dc 278 Gene3D G3DSA:3.40.50.720 1 275 2.9E-28 T 28-03-2018 CU254_RS20810 d6edff1e8ac1ff37b25435826ec4f6f4 421 SUPERFAMILY SSF103473 3 419 6.41E-69 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS20810 d6edff1e8ac1ff37b25435826ec4f6f4 421 Gene3D G3DSA:1.20.1250.20 3 199 9.1E-33 T 28-03-2018 CU254_RS20810 d6edff1e8ac1ff37b25435826ec4f6f4 421 Gene3D G3DSA:1.20.1250.20 216 421 9.8E-32 T 28-03-2018 CU254_RS20810 d6edff1e8ac1ff37b25435826ec4f6f4 421 Pfam PF07690 Major Facilitator Superfamily 15 366 2.5E-41 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS20810 d6edff1e8ac1ff37b25435826ec4f6f4 421 ProSitePatterns PS00217 Sugar transport proteins signature 2. 106 131 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CU254_RS18165 583b6fbf710419b813bbd9147ba67d6c 263 Pfam PF13622 Thioesterase-like superfamily 20 255 3.8E-37 T 28-03-2018 CU254_RS18165 583b6fbf710419b813bbd9147ba67d6c 263 SUPERFAMILY SSF54637 134 258 1.29E-8 T 28-03-2018 IPR029069 HotDog domain CU254_RS18165 583b6fbf710419b813bbd9147ba67d6c 263 Gene3D G3DSA:3.10.129.10 35 108 8.0E-6 T 28-03-2018 CU254_RS15745 ad66a04cf25853f02e0c04aa6423310a 282 Gene3D G3DSA:3.40.50.1820 23 273 8.5E-37 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS15745 ad66a04cf25853f02e0c04aa6423310a 282 Pfam PF12697 Alpha/beta hydrolase family 47 265 1.8E-18 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS15745 ad66a04cf25853f02e0c04aa6423310a 282 SUPERFAMILY SSF53474 19 275 4.05E-39 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS09120 cb9a5f120eed4cd506aac3853f774085 439 PRINTS PR01036 Tetracycline resistance protein TetB signature 103 123 7.4E-10 T 28-03-2018 CU254_RS09120 cb9a5f120eed4cd506aac3853f774085 439 PRINTS PR01036 Tetracycline resistance protein TetB signature 133 157 7.4E-10 T 28-03-2018 CU254_RS09120 cb9a5f120eed4cd506aac3853f774085 439 PRINTS PR01036 Tetracycline resistance protein TetB signature 252 277 7.4E-10 T 28-03-2018 CU254_RS09120 cb9a5f120eed4cd506aac3853f774085 439 PRINTS PR01036 Tetracycline resistance protein TetB signature 199 217 7.4E-10 T 28-03-2018 CU254_RS09120 cb9a5f120eed4cd506aac3853f774085 439 Gene3D G3DSA:1.20.1250.20 4 193 1.7E-24 T 28-03-2018 CU254_RS09120 cb9a5f120eed4cd506aac3853f774085 439 SUPERFAMILY SSF103473 1 197 4.19E-52 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS09120 cb9a5f120eed4cd506aac3853f774085 439 SUPERFAMILY SSF103473 232 428 4.19E-52 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS09120 cb9a5f120eed4cd506aac3853f774085 439 Gene3D G3DSA:1.20.1250.20 245 434 1.5E-15 T 28-03-2018 CU254_RS09120 cb9a5f120eed4cd506aac3853f774085 439 Pfam PF07690 Major Facilitator Superfamily 14 388 1.2E-39 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS06540 6290e76a3e4f962d46d2e0edc61a017b 106 Pfam PF03992 Antibiotic biosynthesis monooxygenase 12 83 2.0E-17 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain CU254_RS06540 6290e76a3e4f962d46d2e0edc61a017b 106 Gene3D G3DSA:3.30.70.100 2 106 4.6E-24 T 28-03-2018 CU254_RS06540 6290e76a3e4f962d46d2e0edc61a017b 106 SUPERFAMILY SSF54909 1 103 1.44E-29 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS10630 9104c3cae4fd1a1aae58be9b6882d71d 372 SUPERFAMILY SSF51905 2 211 4.66E-36 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS10630 9104c3cae4fd1a1aae58be9b6882d71d 372 SUPERFAMILY SSF51905 330 370 4.66E-36 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS10630 9104c3cae4fd1a1aae58be9b6882d71d 372 TIGRFAM TIGR03364 HpnW_proposed: FAD dependent oxidoreductase TIGR03364 2 365 1.5E-95 T 28-03-2018 IPR017741 FAD-dependent oxidoreductase, HpnW CU254_RS10630 9104c3cae4fd1a1aae58be9b6882d71d 372 Gene3D G3DSA:3.30.9.10 169 314 7.4E-19 T 28-03-2018 CU254_RS10630 9104c3cae4fd1a1aae58be9b6882d71d 372 Gene3D G3DSA:3.50.50.60 315 371 9.7E-4 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS10630 9104c3cae4fd1a1aae58be9b6882d71d 372 Gene3D G3DSA:3.30.9.10 81 168 1.7E-5 T 28-03-2018 CU254_RS10630 9104c3cae4fd1a1aae58be9b6882d71d 372 Gene3D G3DSA:3.50.50.60 1 77 1.4E-4 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS10630 9104c3cae4fd1a1aae58be9b6882d71d 372 Pfam PF01266 FAD dependent oxidoreductase 3 367 1.9E-47 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CU254_RS09265 cd626b971e46b6bf37bdfd96429c9330 308 Gene3D G3DSA:1.10.10.10 1 70 6.6E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS09265 cd626b971e46b6bf37bdfd96429c9330 308 Pfam PF08279 HTH domain 11 56 1.4E-12 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 CU254_RS09265 cd626b971e46b6bf37bdfd96429c9330 308 SUPERFAMILY SSF46785 2 59 2.97E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS09265 cd626b971e46b6bf37bdfd96429c9330 308 PIRSF PIRSF016838 69 307 5.1E-16 T 28-03-2018 IPR028349 Protein PafC CU254_RS09265 cd626b971e46b6bf37bdfd96429c9330 308 PIRSF PIRSF016838 1 54 5.7E-4 T 28-03-2018 IPR028349 Protein PafC CU254_RS09265 cd626b971e46b6bf37bdfd96429c9330 308 Pfam PF13280 WYL domain 137 302 5.9E-32 T 28-03-2018 IPR026881 WYL domain CU254_RS30415 12d10d98dae281f599288efdc279e974 1130 Gene3D G3DSA:3.40.640.10 779 1020 3.9E-52 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS30415 12d10d98dae281f599288efdc279e974 1130 SUPERFAMILY SSF53383 770 1124 1.63E-102 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS30415 12d10d98dae281f599288efdc279e974 1130 Gene3D G3DSA:3.40.47.10 7 300 1.8E-75 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS30415 12d10d98dae281f599288efdc279e974 1130 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 15 288 9.3E-67 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CU254_RS30415 12d10d98dae281f599288efdc279e974 1130 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 974 983 - T 28-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 CU254_RS30415 12d10d98dae281f599288efdc279e974 1130 Pfam PF00155 Aminotransferase class I and II 777 1119 2.4E-48 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CU254_RS30415 12d10d98dae281f599288efdc279e974 1130 SUPERFAMILY SSF47336 635 725 2.09E-9 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS30415 12d10d98dae281f599288efdc279e974 1130 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 412 498 5.1E-13 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CU254_RS30415 12d10d98dae281f599288efdc279e974 1130 Gene3D G3DSA:3.40.47.10 303 459 1.5E-44 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS30415 12d10d98dae281f599288efdc279e974 1130 SUPERFAMILY SSF53901 184 406 3.05E-75 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS30415 12d10d98dae281f599288efdc279e974 1130 SUPERFAMILY SSF53901 13 134 3.05E-75 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS30415 12d10d98dae281f599288efdc279e974 1130 SUPERFAMILY SSF53901 436 457 3.05E-75 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS30415 12d10d98dae281f599288efdc279e974 1130 SMART SM00825 Beta-ketoacyl synthase 17 461 1.6E-111 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CU254_RS30415 12d10d98dae281f599288efdc279e974 1130 Pfam PF00550 Phosphopantetheine attachment site 642 705 1.7E-4 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS30415 12d10d98dae281f599288efdc279e974 1130 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 296 410 3.9E-29 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CU254_RS30415 12d10d98dae281f599288efdc279e974 1130 Gene3D G3DSA:1.10.1200.10 631 745 1.4E-8 T 28-03-2018 CU254_RS30415 12d10d98dae281f599288efdc279e974 1130 Gene3D G3DSA:3.90.1150.10 1021 1129 1.2E-20 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS35470 f4d0a3bcb21fecbef9ee286077fc7624 274 Pfam PF08543 Phosphomethylpyrimidine kinase 15 264 6.7E-86 T 28-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 CU254_RS35470 f4d0a3bcb21fecbef9ee286077fc7624 274 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 214 227 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CU254_RS35470 f4d0a3bcb21fecbef9ee286077fc7624 274 Gene3D G3DSA:3.40.1190.20 4 273 4.4E-56 T 28-03-2018 IPR029056 Ribokinase-like CU254_RS35470 f4d0a3bcb21fecbef9ee286077fc7624 274 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 8 266 6.0E-86 T 28-03-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CU254_RS35470 f4d0a3bcb21fecbef9ee286077fc7624 274 SUPERFAMILY SSF53613 6 269 2.03E-71 T 28-03-2018 IPR029056 Ribokinase-like CU254_RS39185 91c68e66a2584ffaa8d7bae216ab8f36 439 Gene3D G3DSA:3.40.640.10 64 316 4.6E-55 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS39185 91c68e66a2584ffaa8d7bae216ab8f36 439 SUPERFAMILY SSF53383 23 411 2.53E-110 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS39185 91c68e66a2584ffaa8d7bae216ab8f36 439 Pfam PF00155 Aminotransferase class I and II 74 406 1.9E-37 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CU254_RS39185 91c68e66a2584ffaa8d7bae216ab8f36 439 Gene3D G3DSA:3.90.1150.10 317 414 4.9E-32 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS17720 76a45cecb470568e98dfa5163089ecc6 406 SUPERFAMILY SSF103473 24 392 1.05E-33 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS17720 76a45cecb470568e98dfa5163089ecc6 406 Gene3D G3DSA:1.20.1250.20 10 201 5.6E-13 T 28-03-2018 CU254_RS17720 76a45cecb470568e98dfa5163089ecc6 406 Gene3D G3DSA:1.20.1250.20 202 392 9.2E-14 T 28-03-2018 CU254_RS17720 76a45cecb470568e98dfa5163089ecc6 406 Pfam PF05977 Transmembrane secretion effector 35 390 2.2E-23 T 28-03-2018 IPR010290 Transmembrane secretion effector CU254_RS19335 65e4562072f9dfb79c134329c9d0c451 281 Gene3D G3DSA:1.10.3470.10 5 273 1.3E-24 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CU254_RS19335 65e4562072f9dfb79c134329c9d0c451 281 Pfam PF00950 ABC 3 transport family 15 260 6.2E-32 T 28-03-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 CU254_RS19335 65e4562072f9dfb79c134329c9d0c451 281 SUPERFAMILY SSF81345 16 258 1.7E-20 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CU254_RS00075 bf876481860683f3a979534d30af229b 387 SUPERFAMILY SSF55874 270 382 1.88E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS00075 bf876481860683f3a979534d30af229b 387 Pfam PF07730 Histidine kinase 185 248 1.4E-16 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CU254_RS00075 bf876481860683f3a979534d30af229b 387 Gene3D G3DSA:3.30.565.10 259 387 4.1E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS05660 c48070fd7103f44c016de6a2ec2f80da 396 SUPERFAMILY SSF48264 18 396 1.02E-87 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS05660 c48070fd7103f44c016de6a2ec2f80da 396 PRINTS PR00359 B-class P450 signature 196 218 1.9E-56 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS05660 c48070fd7103f44c016de6a2ec2f80da 396 PRINTS PR00359 B-class P450 signature 289 316 1.9E-56 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS05660 c48070fd7103f44c016de6a2ec2f80da 396 PRINTS PR00359 B-class P450 signature 159 174 1.9E-56 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS05660 c48070fd7103f44c016de6a2ec2f80da 396 PRINTS PR00359 B-class P450 signature 338 347 1.9E-56 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS05660 c48070fd7103f44c016de6a2ec2f80da 396 PRINTS PR00359 B-class P450 signature 317 332 1.9E-56 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS05660 c48070fd7103f44c016de6a2ec2f80da 396 PRINTS PR00359 B-class P450 signature 142 158 1.9E-56 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS05660 c48070fd7103f44c016de6a2ec2f80da 396 PRINTS PR00359 B-class P450 signature 272 283 1.9E-56 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS05660 c48070fd7103f44c016de6a2ec2f80da 396 PRINTS PR00359 B-class P450 signature 347 358 1.9E-56 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS05660 c48070fd7103f44c016de6a2ec2f80da 396 PRINTS PR00359 B-class P450 signature 95 106 1.9E-56 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS05660 c48070fd7103f44c016de6a2ec2f80da 396 Pfam PF00067 Cytochrome P450 218 368 1.5E-23 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS05660 c48070fd7103f44c016de6a2ec2f80da 396 Gene3D G3DSA:1.10.630.10 10 396 7.1E-64 T 28-03-2018 CU254_RS05660 c48070fd7103f44c016de6a2ec2f80da 396 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 340 349 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CU254_RS05660 c48070fd7103f44c016de6a2ec2f80da 396 PRINTS PR00385 P450 superfamily signature 272 283 3.6E-8 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS05660 c48070fd7103f44c016de6a2ec2f80da 396 PRINTS PR00385 P450 superfamily signature 338 347 3.6E-8 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS05660 c48070fd7103f44c016de6a2ec2f80da 396 PRINTS PR00385 P450 superfamily signature 237 254 3.6E-8 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS05660 c48070fd7103f44c016de6a2ec2f80da 396 PRINTS PR00385 P450 superfamily signature 347 358 3.6E-8 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS22020 b927b208d4c1169a5777fd37f86afdde 162 Pfam PF11239 Protein of unknown function (DUF3040) 65 142 3.8E-12 T 28-03-2018 IPR021401 Protein of unknown function DUF3040 CU254_RS25590 16a9d04d34d4873589ff080912fac01e 456 Pfam PF07690 Major Facilitator Superfamily 260 432 7.0E-10 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS25590 16a9d04d34d4873589ff080912fac01e 456 SUPERFAMILY SSF103473 9 439 5.36E-60 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS25590 16a9d04d34d4873589ff080912fac01e 456 Pfam PF00083 Sugar (and other) transporter 30 231 1.1E-20 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CU254_RS25590 16a9d04d34d4873589ff080912fac01e 456 Gene3D G3DSA:1.20.1250.20 232 454 7.8E-18 T 28-03-2018 CU254_RS25590 16a9d04d34d4873589ff080912fac01e 456 Gene3D G3DSA:1.20.1250.20 22 231 7.5E-23 T 28-03-2018 CU254_RS33450 493e627b97ba160387001429618db025 416 Pfam PF13556 PucR C-terminal helix-turn-helix domain 348 402 6.5E-13 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CU254_RS07025 3796cd666c7297fbc9a2d2458b7dc457 200 Pfam PF00694 Aconitase C-terminal domain 1 114 1.4E-23 T 28-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 CU254_RS07025 3796cd666c7297fbc9a2d2458b7dc457 200 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 179 7.2E-54 T 28-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 CU254_RS07025 3796cd666c7297fbc9a2d2458b7dc457 200 Gene3D G3DSA:3.20.19.10 1 168 9.2E-44 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CU254_RS07025 3796cd666c7297fbc9a2d2458b7dc457 200 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 191 39.212 T 28-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 CU254_RS07025 3796cd666c7297fbc9a2d2458b7dc457 200 SUPERFAMILY SSF52016 1 188 4.51E-52 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CU254_RS30315 73308f668bf8749034c4342f3ab3eda7 227 SUPERFAMILY SSF53474 3 224 1.25E-37 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS30315 73308f668bf8749034c4342f3ab3eda7 227 Gene3D G3DSA:3.40.50.1820 4 227 1.9E-33 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS30315 73308f668bf8749034c4342f3ab3eda7 227 Pfam PF00326 Prolyl oligopeptidase family 97 205 5.2E-9 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CU254_RS24270 cb9dc2013f6ca96455bb2db3e3498da6 226 SMART SM00862 147 223 1.3E-21 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS24270 cb9dc2013f6ca96455bb2db3e3498da6 226 SUPERFAMILY SSF46894 131 223 6.24E-27 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS24270 cb9dc2013f6ca96455bb2db3e3498da6 226 SUPERFAMILY SSF52172 4 122 3.56E-42 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS24270 cb9dc2013f6ca96455bb2db3e3498da6 226 Gene3D G3DSA:3.40.50.2300 2 125 6.2E-40 T 28-03-2018 CU254_RS24270 cb9dc2013f6ca96455bb2db3e3498da6 226 Pfam PF00072 Response regulator receiver domain 4 112 1.3E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS24270 cb9dc2013f6ca96455bb2db3e3498da6 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 223 6.5E-23 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS24270 cb9dc2013f6ca96455bb2db3e3498da6 226 Gene3D G3DSA:1.10.10.10 126 226 1.4E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS24270 cb9dc2013f6ca96455bb2db3e3498da6 226 SMART SM00448 2 112 6.2E-45 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS10280 028ea755ba5403b3dd1a905ef5cbfdd1 1079 Hamap MF_02050 Fused isobutyryl-CoA mutase [icmF]. 12 1079 16.676 T 28-03-2018 IPR033669 Fused isobutyryl-CoA mutase GO:0003924|GO:0005525|GO:0006637|GO:0031419|GO:0034784|GO:0047727 CU254_RS10280 028ea755ba5403b3dd1a905ef5cbfdd1 1079 Gene3D G3DSA:3.40.50.300 194 403 1.2E-28 T 28-03-2018 CU254_RS10280 028ea755ba5403b3dd1a905ef5cbfdd1 1079 Pfam PF02310 B12 binding domain 14 106 2.0E-10 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CU254_RS10280 028ea755ba5403b3dd1a905ef5cbfdd1 1079 Pfam PF01642 Methylmalonyl-CoA mutase 543 1073 2.9E-143 T 28-03-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CU254_RS10280 028ea755ba5403b3dd1a905ef5cbfdd1 1079 SUPERFAMILY SSF51703 507 1075 3.4E-152 T 28-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CU254_RS10280 028ea755ba5403b3dd1a905ef5cbfdd1 1079 Gene3D G3DSA:3.40.50.280 9 149 6.9E-24 T 28-03-2018 CU254_RS10280 028ea755ba5403b3dd1a905ef5cbfdd1 1079 SUPERFAMILY SSF52242 7 144 3.92E-40 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CU254_RS10280 028ea755ba5403b3dd1a905ef5cbfdd1 1079 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 708 1078 1.1E-95 T 28-03-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CU254_RS10280 028ea755ba5403b3dd1a905ef5cbfdd1 1079 SUPERFAMILY SSF52540 154 408 6.5E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS10280 028ea755ba5403b3dd1a905ef5cbfdd1 1079 Pfam PF03308 ArgK protein 166 398 4.2E-42 T 28-03-2018 CU254_RS10280 028ea755ba5403b3dd1a905ef5cbfdd1 1079 Gene3D G3DSA:3.20.20.240 531 1075 3.2E-193 T 28-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CU254_RS00370 cbcc08c96e3056d0bbf220555de33620 131 SUPERFAMILY SSF54593 6 128 1.27E-13 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS00370 cbcc08c96e3056d0bbf220555de33620 131 Gene3D G3DSA:3.10.180.10 5 127 3.1E-14 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS40575 da3841e668bb00b69f85c70a5a7ae4cd 332 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 239 328 3.8E-35 T 28-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CU254_RS40575 da3841e668bb00b69f85c70a5a7ae4cd 332 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 110 190 3.4E-26 T 28-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CU254_RS40575 da3841e668bb00b69f85c70a5a7ae4cd 332 Gene3D G3DSA:3.40.47.10 165 327 5.1E-39 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS40575 da3841e668bb00b69f85c70a5a7ae4cd 332 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 11 328 7.7E-98 T 28-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CU254_RS40575 da3841e668bb00b69f85c70a5a7ae4cd 332 SUPERFAMILY SSF53901 7 329 3.89E-60 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS40575 da3841e668bb00b69f85c70a5a7ae4cd 332 Gene3D G3DSA:3.40.47.10 9 164 2.5E-31 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS40575 da3841e668bb00b69f85c70a5a7ae4cd 332 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 9 328 61.787 T 28-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CU254_RS29455 c611fe1c04313c34fe2998e737c1ee20 453 SUPERFAMILY SSF56601 20 327 7.45E-68 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CU254_RS29455 c611fe1c04313c34fe2998e737c1ee20 453 Gene3D G3DSA:3.40.710.10 2 343 1.2E-66 T 28-03-2018 CU254_RS29455 c611fe1c04313c34fe2998e737c1ee20 453 Pfam PF00144 Beta-lactamase 27 330 1.3E-53 T 28-03-2018 IPR001466 Beta-lactamase-related CU254_RS19435 903d7ff0988bd23c3f7b99942ea11f1d 330 Pfam PF00248 Aldo/keto reductase family 17 310 4.9E-67 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS19435 903d7ff0988bd23c3f7b99942ea11f1d 330 PRINTS PR00069 Aldo-keto reductase signature 140 157 6.9E-6 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CU254_RS19435 903d7ff0988bd23c3f7b99942ea11f1d 330 PRINTS PR00069 Aldo-keto reductase signature 43 67 6.9E-6 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CU254_RS19435 903d7ff0988bd23c3f7b99942ea11f1d 330 PRINTS PR00069 Aldo-keto reductase signature 109 127 6.9E-6 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CU254_RS19435 903d7ff0988bd23c3f7b99942ea11f1d 330 Gene3D G3DSA:3.20.20.100 1 328 2.1E-95 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS19435 903d7ff0988bd23c3f7b99942ea11f1d 330 SUPERFAMILY SSF51430 5 311 1.57E-93 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS01000 7afc16be54696836076284f256b7d4da 395 SUPERFAMILY SSF141523 243 365 5.89E-22 T 28-03-2018 CU254_RS01000 7afc16be54696836076284f256b7d4da 395 Gene3D G3DSA:2.40.440.10 239 367 3.1E-23 T 28-03-2018 CU254_RS01000 7afc16be54696836076284f256b7d4da 395 Pfam PF03734 L,D-transpeptidase catalytic domain 245 365 3.0E-16 T 28-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CU254_RS13555 5fdff2691307e0fa7a3dd3abba28a333 274 Pfam PF06966 Protein of unknown function (DUF1295) 19 255 1.2E-48 T 28-03-2018 IPR010721 Protein of unknown function DUF1295 CU254_RS22550 0a081b18fb6e969fc7860c066f018a13 463 Pfam PF02447 GntP family permease 13 458 1.5E-124 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CU254_RS22550 0a081b18fb6e969fc7860c066f018a13 463 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 14 461 1.3E-110 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CU254_RS22550 0a081b18fb6e969fc7860c066f018a13 463 PIRSF PIRSF002746 7 463 1.6E-146 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CU254_RS29060 a730341c91e287f4983a2afc555e7188 213 Gene3D G3DSA:3.40.50.880 1 213 1.1E-43 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS29060 a730341c91e287f4983a2afc555e7188 213 SUPERFAMILY SSF52317 1 204 1.54E-31 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS29060 a730341c91e287f4983a2afc555e7188 213 Pfam PF01965 DJ-1/PfpI family 107 185 8.5E-11 T 28-03-2018 IPR002818 DJ-1/PfpI CU254_RS11020 180bdf8f015ae7a2e949947ab25ba9a1 537 SMART SM00481 64 139 5.1E-7 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CU254_RS11020 180bdf8f015ae7a2e949947ab25ba9a1 537 SUPERFAMILY SSF89550 199 240 3.34E-18 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CU254_RS11020 180bdf8f015ae7a2e949947ab25ba9a1 537 SUPERFAMILY SSF89550 290 310 3.34E-18 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CU254_RS11020 180bdf8f015ae7a2e949947ab25ba9a1 537 SUPERFAMILY SSF89550 60 148 3.34E-18 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CU254_RS11020 180bdf8f015ae7a2e949947ab25ba9a1 537 Gene3D G3DSA:3.20.20.140 56 317 2.0E-14 T 28-03-2018 CU254_RS13630 c041ac1f27976ddc10ca4a80c1296c6d 66 Gene3D G3DSA:1.20.140.10 12 66 3.3E-6 T 28-03-2018 CU254_RS13630 c041ac1f27976ddc10ca4a80c1296c6d 66 SUPERFAMILY SSF47203 41 65 2.9E-5 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS26595 0795dd329273763c2e0747464c1c0af4 566 SUPERFAMILY SSF56014 173 331 1.2E-45 T 28-03-2018 CU254_RS26595 0795dd329273763c2e0747464c1c0af4 566 SUPERFAMILY SSF55124 303 434 2.94E-20 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CU254_RS26595 0795dd329273763c2e0747464c1c0af4 566 SUPERFAMILY SSF55124 22 172 1.96E-35 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CU254_RS26595 0795dd329273763c2e0747464c1c0af4 566 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 102 163 1.0E-16 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CU254_RS26595 0795dd329273763c2e0747464c1c0af4 566 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 346 411 3.5E-15 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CU254_RS26595 0795dd329273763c2e0747464c1c0af4 566 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 472 488 - T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CU254_RS26595 0795dd329273763c2e0747464c1c0af4 566 SUPERFAMILY SSF56014 419 561 1.31E-36 T 28-03-2018 CU254_RS26595 0795dd329273763c2e0747464c1c0af4 566 Gene3D G3DSA:3.30.413.10 422 564 5.5E-28 T 28-03-2018 CU254_RS26595 0795dd329273763c2e0747464c1c0af4 566 Gene3D G3DSA:3.90.480.10 289 418 1.8E-30 T 28-03-2018 CU254_RS26595 0795dd329273763c2e0747464c1c0af4 566 Gene3D G3DSA:3.30.413.10 174 288 2.3E-25 T 28-03-2018 CU254_RS26595 0795dd329273763c2e0747464c1c0af4 566 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 173 325 2.5E-38 T 28-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CU254_RS26595 0795dd329273763c2e0747464c1c0af4 566 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 423 556 1.7E-11 T 28-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CU254_RS26595 0795dd329273763c2e0747464c1c0af4 566 PRINTS PR00397 Sirohaem Fe-binding site signature 423 441 4.9E-10 T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CU254_RS26595 0795dd329273763c2e0747464c1c0af4 566 PRINTS PR00397 Sirohaem Fe-binding site signature 472 490 4.9E-10 T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CU254_RS02065 8cf377103cd7c95ab6b74dcc2af8f43c 258 PRINTS PR00599 Methionine aminopeptidase-1 signature 90 106 2.5E-21 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CU254_RS02065 8cf377103cd7c95ab6b74dcc2af8f43c 258 PRINTS PR00599 Methionine aminopeptidase-1 signature 67 80 2.5E-21 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CU254_RS02065 8cf377103cd7c95ab6b74dcc2af8f43c 258 PRINTS PR00599 Methionine aminopeptidase-1 signature 166 178 2.5E-21 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CU254_RS02065 8cf377103cd7c95ab6b74dcc2af8f43c 258 PRINTS PR00599 Methionine aminopeptidase-1 signature 197 209 2.5E-21 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CU254_RS02065 8cf377103cd7c95ab6b74dcc2af8f43c 258 Hamap MF_01974 Methionine aminopeptidase [map]. 2 255 39.008 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CU254_RS02065 8cf377103cd7c95ab6b74dcc2af8f43c 258 Pfam PF00557 Metallopeptidase family M24 11 246 2.4E-47 T 28-03-2018 IPR000994 Peptidase M24 CU254_RS02065 8cf377103cd7c95ab6b74dcc2af8f43c 258 Gene3D G3DSA:3.90.230.10 1 255 8.3E-75 T 28-03-2018 CU254_RS02065 8cf377103cd7c95ab6b74dcc2af8f43c 258 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 2 253 1.3E-85 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CU254_RS02065 8cf377103cd7c95ab6b74dcc2af8f43c 258 SUPERFAMILY SSF55920 1 253 2.09E-80 T 28-03-2018 IPR000994 Peptidase M24 CU254_RS02065 8cf377103cd7c95ab6b74dcc2af8f43c 258 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 172 190 - T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CU254_RS38565 ce3588c3c64c82dabf618ef34ec119c7 473 Pfam PF07687 Peptidase dimerisation domain 207 366 4.3E-11 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CU254_RS38565 ce3588c3c64c82dabf618ef34ec119c7 473 Gene3D G3DSA:3.30.70.360 213 379 2.3E-32 T 28-03-2018 CU254_RS38565 ce3588c3c64c82dabf618ef34ec119c7 473 Gene3D G3DSA:3.40.630.10 9 212 1.2E-22 T 28-03-2018 CU254_RS38565 ce3588c3c64c82dabf618ef34ec119c7 473 SUPERFAMILY SSF53187 384 469 2.2E-46 T 28-03-2018 CU254_RS38565 ce3588c3c64c82dabf618ef34ec119c7 473 SUPERFAMILY SSF53187 10 209 2.2E-46 T 28-03-2018 CU254_RS38565 ce3588c3c64c82dabf618ef34ec119c7 473 Pfam PF01546 Peptidase family M20/M25/M40 95 468 6.1E-22 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CU254_RS42615 cf361e4d35d84948c9f025f6e711da23 300 SUPERFAMILY SSF55811 137 284 1.35E-11 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CU254_RS42615 cf361e4d35d84948c9f025f6e711da23 300 Gene3D G3DSA:3.90.79.10 145 300 1.3E-15 T 28-03-2018 CU254_RS42615 cf361e4d35d84948c9f025f6e711da23 300 Pfam PF00293 NUDIX domain 150 293 4.6E-6 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CU254_RS35060 ae1353cf06dc1d3fc9b3d0aa1a4bb1a1 498 PIRSF PIRSF012666 1 497 4.4E-203 T 28-03-2018 IPR016602 Uncharacterised conserved protein UCP012666 CU254_RS35060 ae1353cf06dc1d3fc9b3d0aa1a4bb1a1 498 SUPERFAMILY SSF55931 38 153 1.77E-51 T 28-03-2018 CU254_RS35060 ae1353cf06dc1d3fc9b3d0aa1a4bb1a1 498 SUPERFAMILY SSF55931 183 471 1.77E-51 T 28-03-2018 CU254_RS35060 ae1353cf06dc1d3fc9b3d0aa1a4bb1a1 498 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 194 257 3.2E-6 T 28-03-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CU254_RS29675 438440d01654c445ab9cd359962b744d 479 SUPERFAMILY SSF54373 266 423 1.18E-28 T 28-03-2018 CU254_RS29675 438440d01654c445ab9cd359962b744d 479 Gene3D G3DSA:3.30.560.10 98 434 1.2E-70 T 28-03-2018 CU254_RS29675 438440d01654c445ab9cd359962b744d 479 PIRSF PIRSF000137 1 305 2.9E-73 T 28-03-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CU254_RS29675 438440d01654c445ab9cd359962b744d 479 PIRSF PIRSF000137 308 479 1.0E-39 T 28-03-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CU254_RS29675 438440d01654c445ab9cd359962b744d 479 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 230 244 - T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CU254_RS29675 438440d01654c445ab9cd359962b744d 479 Gene3D G3DSA:4.10.450.10 46 97 5.6E-26 T 28-03-2018 CU254_RS29675 438440d01654c445ab9cd359962b744d 479 Pfam PF00732 GMC oxidoreductase 1 271 4.5E-59 T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CU254_RS29675 438440d01654c445ab9cd359962b744d 479 Pfam PF05199 GMC oxidoreductase 341 472 1.5E-34 T 28-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 CU254_RS29675 438440d01654c445ab9cd359962b744d 479 Gene3D G3DSA:3.40.50.720 1 45 5.6E-4 T 28-03-2018 CU254_RS29675 438440d01654c445ab9cd359962b744d 479 SUPERFAMILY SSF51905 2 264 1.23E-68 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS29675 438440d01654c445ab9cd359962b744d 479 SUPERFAMILY SSF51905 422 478 1.23E-68 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS32325 06e63002e84e0de5efd0e8f93ccee1f7 308 Pfam PF00781 Diacylglycerol kinase catalytic domain 3 121 2.1E-27 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CU254_RS32325 06e63002e84e0de5efd0e8f93ccee1f7 308 SUPERFAMILY SSF111331 2 307 4.14E-53 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain CU254_RS32325 06e63002e84e0de5efd0e8f93ccee1f7 308 SMART SM00046 2 136 3.9E-12 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CU254_RS32325 06e63002e84e0de5efd0e8f93ccee1f7 308 Gene3D G3DSA:3.40.50.10330 1 133 1.4E-29 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 CU254_RS30545 75f964dc7551afc586155b8d5e5e6455 133 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 1 112 1.0E-19 T 28-03-2018 IPR024412 Lsr2 CU254_RS30545 75f964dc7551afc586155b8d5e5e6455 133 Pfam PF11774 Lsr2 1 112 1.2E-39 T 28-03-2018 IPR024412 Lsr2 CU254_RS02055 be900b923f2f9ce6f32159f84b4016a5 435 Pfam PF00344 SecY translocase 72 418 3.1E-114 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CU254_RS02055 be900b923f2f9ce6f32159f84b4016a5 435 Gene3D G3DSA:1.10.3370.10 1 435 5.5E-156 T 28-03-2018 CU254_RS02055 be900b923f2f9ce6f32159f84b4016a5 435 ProSitePatterns PS00756 Protein secY signature 2. 173 190 - T 28-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CU254_RS02055 be900b923f2f9ce6f32159f84b4016a5 435 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 430 3.9E-130 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CU254_RS02055 be900b923f2f9ce6f32159f84b4016a5 435 SUPERFAMILY SSF103491 2 425 1.03E-120 T 28-03-2018 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CU254_RS02055 be900b923f2f9ce6f32159f84b4016a5 435 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 434 29.207 T 28-03-2018 IPR026593 Protein translocase subunit SecY CU254_RS02055 be900b923f2f9ce6f32159f84b4016a5 435 PIRSF PIRSF004557 1 435 9.0E-119 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CU254_RS02055 be900b923f2f9ce6f32159f84b4016a5 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 367 385 4.5E-101 T 28-03-2018 CU254_RS02055 be900b923f2f9ce6f32159f84b4016a5 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 154 179 4.5E-101 T 28-03-2018 CU254_RS02055 be900b923f2f9ce6f32159f84b4016a5 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 403 421 4.5E-101 T 28-03-2018 CU254_RS02055 be900b923f2f9ce6f32159f84b4016a5 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 312 334 4.5E-101 T 28-03-2018 CU254_RS02055 be900b923f2f9ce6f32159f84b4016a5 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 71 91 4.5E-101 T 28-03-2018 CU254_RS02055 be900b923f2f9ce6f32159f84b4016a5 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 180 203 4.5E-101 T 28-03-2018 CU254_RS02055 be900b923f2f9ce6f32159f84b4016a5 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 267 286 4.5E-101 T 28-03-2018 CU254_RS02055 be900b923f2f9ce6f32159f84b4016a5 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 112 135 4.5E-101 T 28-03-2018 CU254_RS02055 be900b923f2f9ce6f32159f84b4016a5 435 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 4.5E-101 T 28-03-2018 CU254_RS02395 e7bc780f18486d88c2cdf4872054de8e 313 Gene3D G3DSA:1.10.1660.10 11 189 7.5E-15 T 28-03-2018 CU254_RS02395 e7bc780f18486d88c2cdf4872054de8e 313 Pfam PF13411 MerR HTH family regulatory protein 15 77 7.4E-14 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS02395 e7bc780f18486d88c2cdf4872054de8e 313 SUPERFAMILY SSF46955 13 99 1.74E-12 T 28-03-2018 IPR009061 Putative DNA-binding domain CU254_RS02395 e7bc780f18486d88c2cdf4872054de8e 313 SMART SM00422 12 81 6.4E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS02395 e7bc780f18486d88c2cdf4872054de8e 313 Gene3D G3DSA:3.40.50.280 190 310 4.9E-9 T 28-03-2018 CU254_RS21415 0d677e5381a90aac7500108c4b3f9246 194 Pfam PF00753 Metallo-beta-lactamase superfamily 9 173 1.6E-26 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS21415 0d677e5381a90aac7500108c4b3f9246 194 SMART SM00849 12 173 3.0E-31 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS21415 0d677e5381a90aac7500108c4b3f9246 194 SUPERFAMILY SSF56281 12 189 3.66E-47 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS21415 0d677e5381a90aac7500108c4b3f9246 194 Gene3D G3DSA:3.60.15.10 1 191 1.9E-43 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS32520 16c79027b20ed5c41189a3ab4e751ef3 95 Pfam PF05534 HicB family 4 35 4.6E-7 T 28-03-2018 IPR008651 Uncharacterised protein family HicB CU254_RS32520 16c79027b20ed5c41189a3ab4e751ef3 95 Gene3D G3DSA:1.10.1220.10 1 37 9.4E-13 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CU254_RS32520 16c79027b20ed5c41189a3ab4e751ef3 95 SUPERFAMILY SSF47598 2 47 4.45E-11 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 CU254_RS27410 e9fade5ae65d87167f434ae2f105aafc 300 Gene3D G3DSA:3.40.50.720 4 298 1.5E-29 T 28-03-2018 CU254_RS27410 e9fade5ae65d87167f434ae2f105aafc 300 Pfam PF05368 NmrA-like family 7 241 3.2E-45 T 28-03-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 CU254_RS27410 e9fade5ae65d87167f434ae2f105aafc 300 SUPERFAMILY SSF51735 7 294 1.86E-61 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS05630 c0db005f21c0a9ada4242dda861ab239 134 Pfam PF13411 MerR HTH family regulatory protein 4 69 7.9E-16 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS05630 c0db005f21c0a9ada4242dda861ab239 134 Gene3D G3DSA:1.10.1660.10 1 57 9.5E-18 T 28-03-2018 CU254_RS05630 c0db005f21c0a9ada4242dda861ab239 134 SUPERFAMILY SSF46955 4 121 9.89E-25 T 28-03-2018 IPR009061 Putative DNA-binding domain CU254_RS05630 c0db005f21c0a9ada4242dda861ab239 134 SMART SM00422 4 72 8.6E-15 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS05630 c0db005f21c0a9ada4242dda861ab239 134 Gene3D G3DSA:1.10.1660.10 58 126 3.3E-8 T 28-03-2018 CU254_RS05815 b1699aad573ab809ce436e918f9523ef 538 SUPERFAMILY SSF103473 22 211 2.27E-67 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS05815 b1699aad573ab809ce436e918f9523ef 538 SUPERFAMILY SSF103473 265 436 2.27E-67 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS05815 b1699aad573ab809ce436e918f9523ef 538 SUPERFAMILY SSF103473 507 535 2.27E-67 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS05815 b1699aad573ab809ce436e918f9523ef 538 Pfam PF07690 Major Facilitator Superfamily 29 426 5.9E-56 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS05815 b1699aad573ab809ce436e918f9523ef 538 Gene3D G3DSA:1.20.1250.20 273 536 3.4E-30 T 28-03-2018 CU254_RS05815 b1699aad573ab809ce436e918f9523ef 538 PRINTS PR01036 Tetracycline resistance protein TetB signature 27 51 1.2E-7 T 28-03-2018 CU254_RS05815 b1699aad573ab809ce436e918f9523ef 538 PRINTS PR01036 Tetracycline resistance protein TetB signature 353 373 1.2E-7 T 28-03-2018 CU254_RS05815 b1699aad573ab809ce436e918f9523ef 538 PRINTS PR01036 Tetracycline resistance protein TetB signature 118 138 1.2E-7 T 28-03-2018 CU254_RS05815 b1699aad573ab809ce436e918f9523ef 538 PRINTS PR01036 Tetracycline resistance protein TetB signature 148 172 1.2E-7 T 28-03-2018 CU254_RS05815 b1699aad573ab809ce436e918f9523ef 538 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 25 451 2.7E-84 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CU254_RS05815 b1699aad573ab809ce436e918f9523ef 538 Gene3D G3DSA:1.20.1250.20 16 211 1.1E-31 T 28-03-2018 CU254_RS31530 d186b621cce70bc47d5e06a8032ef2f8 265 Hamap MF_00008 Thymidylate synthase [thyA]. 3 265 39.256 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CU254_RS31530 d186b621cce70bc47d5e06a8032ef2f8 265 SUPERFAMILY SSF55831 3 265 4.71E-126 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CU254_RS31530 d186b621cce70bc47d5e06a8032ef2f8 265 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 88 265 1.3E-90 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CU254_RS31530 d186b621cce70bc47d5e06a8032ef2f8 265 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 5 86 2.1E-38 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CU254_RS31530 d186b621cce70bc47d5e06a8032ef2f8 265 ProSitePatterns PS00091 Thymidylate synthase active site. 128 156 - T 28-03-2018 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CU254_RS31530 d186b621cce70bc47d5e06a8032ef2f8 265 Pfam PF00303 Thymidylate synthase 5 265 7.9E-122 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CU254_RS31530 d186b621cce70bc47d5e06a8032ef2f8 265 Gene3D G3DSA:3.30.572.10 1 265 3.8E-129 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CU254_RS31530 d186b621cce70bc47d5e06a8032ef2f8 265 PRINTS PR00108 Thymidylate synthase family signature 199 216 9.2E-49 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CU254_RS31530 d186b621cce70bc47d5e06a8032ef2f8 265 PRINTS PR00108 Thymidylate synthase family signature 161 187 9.2E-49 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CU254_RS31530 d186b621cce70bc47d5e06a8032ef2f8 265 PRINTS PR00108 Thymidylate synthase family signature 117 136 9.2E-49 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CU254_RS31530 d186b621cce70bc47d5e06a8032ef2f8 265 PRINTS PR00108 Thymidylate synthase family signature 143 158 9.2E-49 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CU254_RS31530 d186b621cce70bc47d5e06a8032ef2f8 265 PRINTS PR00108 Thymidylate synthase family signature 44 65 9.2E-49 T 28-03-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CU254_RS18115 b6b1bdfaca5b2cb208ea8c070d6af54b 189 Pfam PF01738 Dienelactone hydrolase family 4 187 8.0E-12 T 28-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 CU254_RS18115 b6b1bdfaca5b2cb208ea8c070d6af54b 189 Gene3D G3DSA:3.40.50.1820 4 189 3.1E-15 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS18115 b6b1bdfaca5b2cb208ea8c070d6af54b 189 SUPERFAMILY SSF53474 4 187 5.18E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS09690 dfa92be2c3afd1f0fb215551a51ab7dd 295 Pfam PF16868 NMT1-like family 20 291 1.1E-47 T 28-03-2018 IPR011852 TRAP transporter solute receptor, TAXI family CU254_RS09690 dfa92be2c3afd1f0fb215551a51ab7dd 295 Gene3D G3DSA:3.40.190.10 124 295 1.7E-31 T 28-03-2018 CU254_RS09690 dfa92be2c3afd1f0fb215551a51ab7dd 295 SUPERFAMILY SSF53850 18 291 2.3E-55 T 28-03-2018 CU254_RS09690 dfa92be2c3afd1f0fb215551a51ab7dd 295 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 14 292 1.6E-60 T 28-03-2018 IPR011852 TRAP transporter solute receptor, TAXI family CU254_RS09690 dfa92be2c3afd1f0fb215551a51ab7dd 295 Gene3D G3DSA:3.40.190.10 12 123 1.2E-11 T 28-03-2018 CU254_RS41190 b7f246ac7313b619d8b635178b5873a5 155 SUPERFAMILY SSF55811 19 148 3.66E-20 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CU254_RS41190 b7f246ac7313b619d8b635178b5873a5 155 Pfam PF00293 NUDIX domain 23 144 4.0E-11 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CU254_RS41190 b7f246ac7313b619d8b635178b5873a5 155 Gene3D G3DSA:3.90.79.10 17 155 1.1E-23 T 28-03-2018 CU254_RS22745 95f5593f8799ba81393f63b7e1730953 955 SMART SM00939 381 604 5.3E-4 T 28-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CU254_RS22745 95f5593f8799ba81393f63b7e1730953 955 Gene3D G3DSA:3.40.50.300 656 897 1.2E-60 T 28-03-2018 CU254_RS22745 95f5593f8799ba81393f63b7e1730953 955 ProSitePatterns PS00211 ABC transporters family signature. 788 802 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS22745 95f5593f8799ba81393f63b7e1730953 955 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 58 339 1.2E-12 T 28-03-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 CU254_RS22745 95f5593f8799ba81393f63b7e1730953 955 Gene3D G3DSA:3.40.50.1820 43 398 1.4E-35 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS22745 95f5593f8799ba81393f63b7e1730953 955 Pfam PF00005 ABC transporter 677 816 1.4E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS22745 95f5593f8799ba81393f63b7e1730953 955 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 481 592 1.3E-8 T 28-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CU254_RS22745 95f5593f8799ba81393f63b7e1730953 955 Gene3D G3DSA:2.60.120.260 399 616 3.7E-22 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS22745 95f5593f8799ba81393f63b7e1730953 955 SUPERFAMILY SSF52540 652 880 2.62E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS22745 95f5593f8799ba81393f63b7e1730953 955 SUPERFAMILY SSF53474 286 386 4.09E-41 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS22745 95f5593f8799ba81393f63b7e1730953 955 SUPERFAMILY SSF53474 15 192 4.09E-41 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS22745 95f5593f8799ba81393f63b7e1730953 955 SUPERFAMILY SSF49785 475 610 6.59E-13 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS22745 95f5593f8799ba81393f63b7e1730953 955 SMART SM00382 684 865 8.6E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS40985 b40730d761dde6cc615136022d949087 275 Pfam PF13671 AAA domain 16 133 2.1E-22 T 28-03-2018 CU254_RS40985 b40730d761dde6cc615136022d949087 275 Gene3D G3DSA:3.40.50.300 27 199 4.4E-17 T 28-03-2018 CU254_RS40985 b40730d761dde6cc615136022d949087 275 SUPERFAMILY SSF52540 3 129 2.47E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS40985 b40730d761dde6cc615136022d949087 275 Gene3D G3DSA:3.40.50.300 2 26 0.0013 T 28-03-2018 CU254_RS32075 98befb16d72b67bff69ab30347646bcd 403 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 132 227 4.6E-24 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CU254_RS32075 98befb16d72b67bff69ab30347646bcd 403 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 244 395 1.5E-37 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS32075 98befb16d72b67bff69ab30347646bcd 403 Gene3D G3DSA:2.40.110.10 134 226 2.3E-36 T 28-03-2018 CU254_RS32075 98befb16d72b67bff69ab30347646bcd 403 Gene3D G3DSA:1.20.140.10 227 403 2.7E-42 T 28-03-2018 CU254_RS32075 98befb16d72b67bff69ab30347646bcd 403 SUPERFAMILY SSF47203 244 397 4.35E-36 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS32075 98befb16d72b67bff69ab30347646bcd 403 SUPERFAMILY SSF56645 13 255 3.4E-46 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS32075 98befb16d72b67bff69ab30347646bcd 403 Gene3D G3DSA:1.10.540.10 1 133 2.1E-14 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS30490 3a5c8d8d5333e1db901a878b98e2debe 117 Gene3D G3DSA:3.40.630.30 1 115 4.4E-17 T 28-03-2018 CU254_RS30490 3a5c8d8d5333e1db901a878b98e2debe 117 SUPERFAMILY SSF55729 4 100 5.75E-21 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS30490 3a5c8d8d5333e1db901a878b98e2debe 117 Pfam PF13302 Acetyltransferase (GNAT) domain 5 95 2.9E-15 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS11715 7e50a4d1ca7d3e185ddd4cf19c24f230 343 TIGRFAM TIGR00534 OpcA: glucose-6-phosphate dehydrogenase assembly protein OpcA 2 302 1.1E-79 T 28-03-2018 IPR004555 Glucose-6-phosphate dehydrogenase assembly protein OpcA CU254_RS11715 7e50a4d1ca7d3e185ddd4cf19c24f230 343 Pfam PF10128 Glucose-6-phosphate dehydrogenase subunit 52 297 2.2E-88 T 28-03-2018 IPR004555 Glucose-6-phosphate dehydrogenase assembly protein OpcA CU254_RS33855 0d8f72b0513a268d98bb5138d71ed6a0 195 Gene3D G3DSA:1.10.10.10 2 94 1.2E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS33855 0d8f72b0513a268d98bb5138d71ed6a0 195 Pfam PF03551 Transcriptional regulator PadR-like family 8 84 5.0E-10 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CU254_RS33855 0d8f72b0513a268d98bb5138d71ed6a0 195 SUPERFAMILY SSF46785 4 176 1.65E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS11685 5dca01bfdfa55fd20f36430478923b9e 261 Gene3D G3DSA:3.20.20.70 1 258 6.0E-100 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS11685 5dca01bfdfa55fd20f36430478923b9e 261 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 6 244 1.5E-55 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CU254_RS11685 5dca01bfdfa55fd20f36430478923b9e 261 Pfam PF00121 Triosephosphate isomerase 6 252 1.7E-88 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CU254_RS11685 5dca01bfdfa55fd20f36430478923b9e 261 ProSitePatterns PS00171 Triosephosphate isomerase active site. 170 180 - T 28-03-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CU254_RS11685 5dca01bfdfa55fd20f36430478923b9e 261 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 3 255 39.728 T 28-03-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CU254_RS11685 5dca01bfdfa55fd20f36430478923b9e 261 SUPERFAMILY SSF51351 2 254 2.09E-90 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CU254_RS28525 67dee0cb53299539dbb8c782af284e1b 210 TIGRFAM TIGR02476 BluB: 5,6-dimethylbenzimidazole synthase 3 201 4.9E-69 T 28-03-2018 IPR012825 5,6-dimethylbenzimidazole synthase BluB KEGG: 00740+1.13.11.79|MetaCyc: PWY-5508|MetaCyc: PWY-5523 CU254_RS28525 67dee0cb53299539dbb8c782af284e1b 210 SUPERFAMILY SSF55469 5 206 1.05E-47 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CU254_RS28525 67dee0cb53299539dbb8c782af284e1b 210 Gene3D G3DSA:3.40.109.10 1 210 2.4E-42 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CU254_RS28525 67dee0cb53299539dbb8c782af284e1b 210 Pfam PF00881 Nitroreductase family 11 175 8.5E-32 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CU254_RS05665 45796cfcd6269a70ec171d4c6476da2d 175 Pfam PF02522 Aminoglycoside 3-N-acetyltransferase 37 170 1.8E-31 T 28-03-2018 IPR003679 Aminoglycoside N(3)-acetyltransferase GO:0046353|GO:0046677 CU254_RS05665 45796cfcd6269a70ec171d4c6476da2d 175 Pfam PF02522 Aminoglycoside 3-N-acetyltransferase 1 36 2.3E-7 T 28-03-2018 IPR003679 Aminoglycoside N(3)-acetyltransferase GO:0046353|GO:0046677 CU254_RS05665 45796cfcd6269a70ec171d4c6476da2d 175 SUPERFAMILY SSF110710 1 172 5.75E-43 T 28-03-2018 CU254_RS34875 f3e78bd49a671c7811264381618270fb 282 SUPERFAMILY SSF56281 1 269 5.11E-30 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS34875 f3e78bd49a671c7811264381618270fb 282 Pfam PF00753 Metallo-beta-lactamase superfamily 34 219 1.2E-21 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS34875 f3e78bd49a671c7811264381618270fb 282 Gene3D G3DSA:3.60.15.10 1 278 8.6E-34 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS34875 f3e78bd49a671c7811264381618270fb 282 SMART SM00849 32 264 4.8E-14 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS05115 d57cd8d7f989b8d917893d6a8a95b3cb 226 SUPERFAMILY SSF53474 4 221 1.42E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS05115 d57cd8d7f989b8d917893d6a8a95b3cb 226 Pfam PF12697 Alpha/beta hydrolase family 4 216 8.5E-16 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS05115 d57cd8d7f989b8d917893d6a8a95b3cb 226 Gene3D G3DSA:3.40.50.1820 4 225 5.2E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS09755 8445562ae53e86d98cd75d865bf65452 213 Gene3D G3DSA:3.10.350.10 138 196 2.1E-9 T 28-03-2018 CU254_RS09755 8445562ae53e86d98cd75d865bf65452 213 Pfam PF01476 LysM domain 146 192 1.6E-7 T 28-03-2018 IPR018392 LysM domain CU254_RS09755 8445562ae53e86d98cd75d865bf65452 213 SMART SM00257 143 192 7.9E-6 T 28-03-2018 IPR018392 LysM domain CU254_RS15775 e9ade5a5b8c57aaa77d812c952953457 423 Pfam PF13535 ATP-grasp domain 134 294 2.7E-9 T 28-03-2018 CU254_RS15775 e9ade5a5b8c57aaa77d812c952953457 423 Gene3D G3DSA:3.30.470.20 93 421 7.1E-27 T 28-03-2018 CU254_RS15775 e9ade5a5b8c57aaa77d812c952953457 423 SUPERFAMILY SSF56059 128 329 2.05E-27 T 28-03-2018 CU254_RS00350 f0b826bd3046e5280c0ec6a5ee9fa9c3 315 SUPERFAMILY SSF46689 210 261 5.07E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS00350 f0b826bd3046e5280c0ec6a5ee9fa9c3 315 SUPERFAMILY SSF46689 263 312 2.86E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS00350 f0b826bd3046e5280c0ec6a5ee9fa9c3 315 SMART SM00342 227 313 4.1E-23 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS00350 f0b826bd3046e5280c0ec6a5ee9fa9c3 315 Pfam PF12833 Helix-turn-helix domain 233 312 1.3E-22 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS00350 f0b826bd3046e5280c0ec6a5ee9fa9c3 315 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 264 309 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CU254_RS00350 f0b826bd3046e5280c0ec6a5ee9fa9c3 315 Gene3D G3DSA:1.10.10.60 208 263 9.6E-11 T 28-03-2018 CU254_RS00350 f0b826bd3046e5280c0ec6a5ee9fa9c3 315 Gene3D G3DSA:1.10.10.60 264 315 1.7E-8 T 28-03-2018 CU254_RS29415 89818d19d3214573ab95dd55b4537dfa 344 Gene3D G3DSA:1.10.1660.10 66 125 7.7E-4 T 28-03-2018 CU254_RS29415 89818d19d3214573ab95dd55b4537dfa 344 Pfam PF02767 DNA polymerase III beta subunit, central domain 121 230 2.6E-11 T 28-03-2018 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CU254_RS29415 89818d19d3214573ab95dd55b4537dfa 344 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 246 338 2.6E-5 T 28-03-2018 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CU254_RS29415 89818d19d3214573ab95dd55b4537dfa 344 SMART SM00422 5 75 2.4E-13 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS29415 89818d19d3214573ab95dd55b4537dfa 344 SMART SM00480 6 336 0.001 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CU254_RS29415 89818d19d3214573ab95dd55b4537dfa 344 SUPERFAMILY SSF46955 4 107 2.01E-21 T 28-03-2018 IPR009061 Putative DNA-binding domain CU254_RS29415 89818d19d3214573ab95dd55b4537dfa 344 SUPERFAMILY SSF55979 117 232 5.73E-10 T 28-03-2018 CU254_RS29415 89818d19d3214573ab95dd55b4537dfa 344 Gene3D G3DSA:3.10.150.10 239 339 5.0E-12 T 28-03-2018 CU254_RS29415 89818d19d3214573ab95dd55b4537dfa 344 Gene3D G3DSA:3.10.150.10 126 234 1.8E-23 T 28-03-2018 CU254_RS29415 89818d19d3214573ab95dd55b4537dfa 344 SUPERFAMILY SSF55979 245 339 1.13E-6 T 28-03-2018 CU254_RS29415 89818d19d3214573ab95dd55b4537dfa 344 Gene3D G3DSA:1.10.1660.10 2 65 3.2E-17 T 28-03-2018 CU254_RS29415 89818d19d3214573ab95dd55b4537dfa 344 Pfam PF13411 MerR HTH family regulatory protein 6 73 2.2E-14 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS38230 cc934ef64aefbda1b311738b3caa4e14 248 SMART SM00382 31 216 1.9E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS38230 cc934ef64aefbda1b311738b3caa4e14 248 Gene3D G3DSA:3.40.50.300 3 229 3.3E-66 T 28-03-2018 CU254_RS38230 cc934ef64aefbda1b311738b3caa4e14 248 SUPERFAMILY SSF52540 7 219 7.64E-69 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS38230 cc934ef64aefbda1b311738b3caa4e14 248 Pfam PF00005 ABC transporter 22 168 6.9E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS38230 cc934ef64aefbda1b311738b3caa4e14 248 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS00185 77718ca8121e91fd9b37400497b6cd63 348 SUPERFAMILY SSF53850 117 272 4.89E-7 T 28-03-2018 CU254_RS00185 77718ca8121e91fd9b37400497b6cd63 348 Gene3D G3DSA:3.40.190.10 116 242 4.3E-7 T 28-03-2018 CU254_RS00185 77718ca8121e91fd9b37400497b6cd63 348 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 30 95 8.3E-12 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS00185 77718ca8121e91fd9b37400497b6cd63 348 SUPERFAMILY SSF46785 29 131 8.63E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS00185 77718ca8121e91fd9b37400497b6cd63 348 Gene3D G3DSA:1.10.10.10 11 115 2.1E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS08280 115f936769dd627c0f317b8a38103672 450 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 18 415 5.2E-73 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CU254_RS08280 115f936769dd627c0f317b8a38103672 450 Gene3D G3DSA:1.20.1250.20 255 450 3.5E-17 T 28-03-2018 CU254_RS08280 115f936769dd627c0f317b8a38103672 450 Gene3D G3DSA:1.20.1250.20 4 197 9.1E-29 T 28-03-2018 CU254_RS08280 115f936769dd627c0f317b8a38103672 450 Pfam PF07690 Major Facilitator Superfamily 18 410 1.5E-42 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS08280 115f936769dd627c0f317b8a38103672 450 PRINTS PR01036 Tetracycline resistance protein TetB signature 17 41 3.0E-7 T 28-03-2018 CU254_RS08280 115f936769dd627c0f317b8a38103672 450 PRINTS PR01036 Tetracycline resistance protein TetB signature 108 128 3.0E-7 T 28-03-2018 CU254_RS08280 115f936769dd627c0f317b8a38103672 450 PRINTS PR01036 Tetracycline resistance protein TetB signature 138 162 3.0E-7 T 28-03-2018 CU254_RS08280 115f936769dd627c0f317b8a38103672 450 PRINTS PR01036 Tetracycline resistance protein TetB signature 203 221 3.0E-7 T 28-03-2018 CU254_RS08280 115f936769dd627c0f317b8a38103672 450 SUPERFAMILY SSF103473 6 195 3.4E-53 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS08280 115f936769dd627c0f317b8a38103672 450 SUPERFAMILY SSF103473 245 448 3.4E-53 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS38725 62a270790d95d4c43c822d48de623077 297 Pfam PF00296 Luciferase-like monooxygenase 20 236 3.7E-26 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS38725 62a270790d95d4c43c822d48de623077 297 TIGRFAM TIGR03621 F420_MSMEG_2516: probable F420-dependent oxidoreductase, MSMEG_2516 family 9 294 2.0E-100 T 28-03-2018 IPR019923 Luciferase-like, F420-dependent oxidoreductase, MSMEG2516, predicted CU254_RS38725 62a270790d95d4c43c822d48de623077 297 SUPERFAMILY SSF51679 9 295 1.44E-46 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS38725 62a270790d95d4c43c822d48de623077 297 Gene3D G3DSA:3.20.20.30 17 297 1.7E-46 T 28-03-2018 CU254_RS16075 1562f93d182536e25742dbcf9ee792e0 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 47 4.4E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS16075 1562f93d182536e25742dbcf9ee792e0 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 54 77 4.4E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS16075 1562f93d182536e25742dbcf9ee792e0 216 SUPERFAMILY SSF46689 24 93 1.2E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS16075 1562f93d182536e25742dbcf9ee792e0 216 Gene3D G3DSA:1.10.357.10 6 206 1.1E-26 T 28-03-2018 CU254_RS16075 1562f93d182536e25742dbcf9ee792e0 216 Pfam PF00440 Bacterial regulatory proteins, tetR family 34 74 2.7E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS27300 5f282423b6f41cb582337edabca70add 615 Pfam PF06210 Protein of unknown function (DUF1003) 79 173 4.3E-11 T 28-03-2018 IPR010406 Protein of unknown function DUF1003 CU254_RS27300 5f282423b6f41cb582337edabca70add 615 Pfam PF06210 Protein of unknown function (DUF1003) 219 312 7.4E-8 T 28-03-2018 IPR010406 Protein of unknown function DUF1003 CU254_RS31700 4d7c969c4b16d67801652a0d08e0398c 451 SUPERFAMILY SSF53383 8 444 2.81E-122 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS31700 4d7c969c4b16d67801652a0d08e0398c 451 Gene3D G3DSA:3.90.1150.10 1 70 4.2E-6 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS31700 4d7c969c4b16d67801652a0d08e0398c 451 Gene3D G3DSA:3.40.640.10 71 321 3.2E-74 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS31700 4d7c969c4b16d67801652a0d08e0398c 451 Gene3D G3DSA:3.90.1150.10 322 451 1.4E-30 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS31700 4d7c969c4b16d67801652a0d08e0398c 451 PIRSF PIRSF000521 26 445 1.0E-25 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CU254_RS31700 4d7c969c4b16d67801652a0d08e0398c 451 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 249 286 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CU254_RS31700 4d7c969c4b16d67801652a0d08e0398c 451 Pfam PF00202 Aminotransferase class-III 27 444 2.6E-92 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CU254_RS29215 5a97a9351b24fb762a39f936fd5d71b2 371 SUPERFAMILY SSF53850 65 356 1.95E-44 T 28-03-2018 CU254_RS29215 5a97a9351b24fb762a39f936fd5d71b2 371 Gene3D G3DSA:3.40.190.10 27 175 1.0E-8 T 28-03-2018 CU254_RS29215 5a97a9351b24fb762a39f936fd5d71b2 371 Gene3D G3DSA:3.40.190.10 176 330 2.7E-31 T 28-03-2018 CU254_RS29215 5a97a9351b24fb762a39f936fd5d71b2 371 Pfam PF13343 Bacterial extracellular solute-binding protein 148 326 2.6E-27 T 28-03-2018 CU254_RS11950 ef5233940ea83053a3f87c90b8f15ac0 203 Gene3D G3DSA:1.10.1740.10 12 95 1.5E-9 T 28-03-2018 CU254_RS11950 ef5233940ea83053a3f87c90b8f15ac0 203 SUPERFAMILY SSF88659 114 179 1.66E-8 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS11950 ef5233940ea83053a3f87c90b8f15ac0 203 Gene3D G3DSA:1.10.10.10 117 174 2.8E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS11950 ef5233940ea83053a3f87c90b8f15ac0 203 SUPERFAMILY SSF88946 17 103 3.22E-8 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS11950 ef5233940ea83053a3f87c90b8f15ac0 203 Pfam PF04545 Sigma-70, region 4 133 177 3.6E-6 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS09200 067c377cd3e04c52cecdb57edd33c2ef 727 SUPERFAMILY SSF82866 458 691 1.57E-30 T 28-03-2018 CU254_RS09200 067c377cd3e04c52cecdb57edd33c2ef 727 SUPERFAMILY SSF82866 140 332 5.62E-31 T 28-03-2018 CU254_RS09200 067c377cd3e04c52cecdb57edd33c2ef 727 Pfam PF03176 MMPL family 45 360 1.0E-69 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CU254_RS09200 067c377cd3e04c52cecdb57edd33c2ef 727 Pfam PF03176 MMPL family 430 691 2.3E-38 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CU254_RS09200 067c377cd3e04c52cecdb57edd33c2ef 727 Gene3D G3DSA:1.20.1640.10 465 689 8.1E-34 T 28-03-2018 CU254_RS09200 067c377cd3e04c52cecdb57edd33c2ef 727 Gene3D G3DSA:1.20.1640.10 124 333 7.7E-34 T 28-03-2018 CU254_RS10555 941c50afa01b57addf1a5e687f962b69 261 Pfam PF01841 Transglutaminase-like superfamily 116 203 5.7E-18 T 28-03-2018 IPR002931 Transglutaminase-like CU254_RS10555 941c50afa01b57addf1a5e687f962b69 261 Gene3D G3DSA:3.90.260.10 134 217 5.2E-5 T 28-03-2018 IPR002931 Transglutaminase-like CU254_RS10555 941c50afa01b57addf1a5e687f962b69 261 SMART SM00460 145 205 7.3E-14 T 28-03-2018 IPR002931 Transglutaminase-like CU254_RS10555 941c50afa01b57addf1a5e687f962b69 261 SUPERFAMILY SSF54001 89 231 1.82E-27 T 28-03-2018 CU254_RS01335 146256773915cce5fc3d55b599702c91 415 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 1 320 6.7E-68 T 28-03-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 CU254_RS01335 146256773915cce5fc3d55b599702c91 415 Pfam PF01494 FAD binding domain 1 172 1.0E-11 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CU254_RS01335 146256773915cce5fc3d55b599702c91 415 Gene3D G3DSA:3.50.50.60 1 153 2.0E-14 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS01335 146256773915cce5fc3d55b599702c91 415 SUPERFAMILY SSF51905 1 168 2.16E-44 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS01335 146256773915cce5fc3d55b599702c91 415 SUPERFAMILY SSF51905 281 363 2.16E-44 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS01335 146256773915cce5fc3d55b599702c91 415 Gene3D G3DSA:3.30.9.10 154 326 7.4E-45 T 28-03-2018 CU254_RS15540 67dd62acb40e1e67580eff4e75156b3a 160 Gene3D G3DSA:3.40.190.10 3 156 4.6E-4 T 28-03-2018 CU254_RS15540 67dd62acb40e1e67580eff4e75156b3a 160 Pfam PF03640 Secreted repeat of unknown function 93 137 3.9E-12 T 28-03-2018 IPR005297 Lipoprotein repeat CU254_RS15540 67dd62acb40e1e67580eff4e75156b3a 160 Pfam PF03640 Secreted repeat of unknown function 44 79 5.2E-7 T 28-03-2018 IPR005297 Lipoprotein repeat CU254_RS34690 90666924456828d17ab253b759dac627 229 SUPERFAMILY SSF56214 7 99 5.06E-13 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CU254_RS34690 90666924456828d17ab253b759dac627 229 SUPERFAMILY SSF56214 106 216 3.84E-21 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CU254_RS34690 90666924456828d17ab253b759dac627 229 Gene3D G3DSA:3.90.470.20 118 217 1.2E-15 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CU254_RS34690 90666924456828d17ab253b759dac627 229 Gene3D G3DSA:3.90.470.20 5 117 1.5E-20 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CU254_RS34690 90666924456828d17ab253b759dac627 229 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 107 187 4.8E-14 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CU254_RS24470 755c11c39a5e8aae9684debdb71d7953 909 Gene3D G3DSA:1.25.40.10 314 607 8.3E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS24470 755c11c39a5e8aae9684debdb71d7953 909 Gene3D G3DSA:1.25.40.10 608 807 6.5E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS24470 755c11c39a5e8aae9684debdb71d7953 909 Gene3D G3DSA:1.25.40.10 808 906 5.6E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS24470 755c11c39a5e8aae9684debdb71d7953 909 Gene3D G3DSA:1.25.40.10 7 301 0.0016 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS24470 755c11c39a5e8aae9684debdb71d7953 909 SUPERFAMILY SSF48452 428 601 3.22E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS24470 755c11c39a5e8aae9684debdb71d7953 909 SUPERFAMILY SSF48452 615 799 1.63E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS03735 a2186a65f7e3abdbf0aa590b507d5bf8 476 Gene3D G3DSA:3.40.630.10 149 476 2.3E-123 T 28-03-2018 CU254_RS03735 a2186a65f7e3abdbf0aa590b507d5bf8 476 SUPERFAMILY SSF53187 160 473 7.22E-103 T 28-03-2018 CU254_RS03735 a2186a65f7e3abdbf0aa590b507d5bf8 476 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 34 123 4.6E-6 T 28-03-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CU254_RS03735 a2186a65f7e3abdbf0aa590b507d5bf8 476 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 324 331 - T 28-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CU254_RS03735 a2186a65f7e3abdbf0aa590b507d5bf8 476 Gene3D G3DSA:3.40.220.10 20 140 2.3E-17 T 28-03-2018 CU254_RS03735 a2186a65f7e3abdbf0aa590b507d5bf8 476 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 165 468 1.0E-109 T 28-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CU254_RS03735 a2186a65f7e3abdbf0aa590b507d5bf8 476 PRINTS PR00481 Cytosol aminopeptidase signature 261 282 8.6E-46 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CU254_RS03735 a2186a65f7e3abdbf0aa590b507d5bf8 476 PRINTS PR00481 Cytosol aminopeptidase signature 239 256 8.6E-46 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CU254_RS03735 a2186a65f7e3abdbf0aa590b507d5bf8 476 PRINTS PR00481 Cytosol aminopeptidase signature 298 319 8.6E-46 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CU254_RS03735 a2186a65f7e3abdbf0aa590b507d5bf8 476 PRINTS PR00481 Cytosol aminopeptidase signature 320 340 8.6E-46 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CU254_RS03735 a2186a65f7e3abdbf0aa590b507d5bf8 476 PRINTS PR00481 Cytosol aminopeptidase signature 349 364 8.6E-46 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CU254_RS03735 a2186a65f7e3abdbf0aa590b507d5bf8 476 SUPERFAMILY SSF52949 38 140 1.53E-5 T 28-03-2018 CU254_RS39255 7dd5a3376b464b893f46841ec874ce8d 211 Pfam PF05258 Protein of unknown function (DUF721) 99 186 2.9E-24 T 28-03-2018 IPR007922 Protein of unknown function DUF721/UPF0232 CU254_RS13125 288d6f0a6e08ff93bf353fcc61cbfbee 309 SUPERFAMILY SSF55120 83 295 6.56E-51 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CU254_RS13125 288d6f0a6e08ff93bf353fcc61cbfbee 309 Gene3D G3DSA:3.30.2350.10 91 294 2.7E-46 T 28-03-2018 CU254_RS13125 288d6f0a6e08ff93bf353fcc61cbfbee 309 Pfam PF00849 RNA pseudouridylate synthase 99 244 5.7E-16 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CU254_RS13125 288d6f0a6e08ff93bf353fcc61cbfbee 309 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 138 152 - T 28-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 CU254_RS06430 841ba51c5acf26b57003fd27c4ae5f33 345 Gene3D G3DSA:2.60.120.10 14 224 1.4E-31 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS06430 841ba51c5acf26b57003fd27c4ae5f33 345 Gene3D G3DSA:2.60.120.10 266 337 2.8E-12 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS06430 841ba51c5acf26b57003fd27c4ae5f33 345 SUPERFAMILY SSF51182 19 340 1.3E-51 T 28-03-2018 IPR011051 RmlC-like cupin domain CU254_RS30375 7b55117e2a3069c28010ae04938b79e2 244 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 233 1.2E-41 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CU254_RS30375 7b55117e2a3069c28010ae04938b79e2 244 Gene3D G3DSA:3.90.226.10 2 208 1.1E-56 T 28-03-2018 CU254_RS30375 7b55117e2a3069c28010ae04938b79e2 244 SUPERFAMILY SSF52096 3 244 8.42E-63 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS30375 7b55117e2a3069c28010ae04938b79e2 244 Gene3D G3DSA:1.10.12.10 209 243 5.0E-6 T 28-03-2018 IPR014748 Crontonase, C-terminal CU254_RS30725 e7834429ae9a0ca53962782be0397100 213 Pfam PF13419 Haloacid dehalogenase-like hydrolase 1 179 2.3E-31 T 28-03-2018 IPR023214 HAD-like domain CU254_RS30725 e7834429ae9a0ca53962782be0397100 213 Gene3D G3DSA:3.40.50.1000 1 193 1.5E-36 T 28-03-2018 IPR023214 HAD-like domain CU254_RS30725 e7834429ae9a0ca53962782be0397100 213 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 49 179 8.9E-18 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CU254_RS30725 e7834429ae9a0ca53962782be0397100 213 SUPERFAMILY SSF56784 1 200 1.07E-46 T 28-03-2018 IPR023214 HAD-like domain CU254_RS26160 6822a71791c8225c6bae5f0b243f884c 594 Gene3D G3DSA:3.50.50.60 2 567 5.9E-46 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS26160 6822a71791c8225c6bae5f0b243f884c 594 SUPERFAMILY SSF51905 3 332 8.43E-38 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS26160 6822a71791c8225c6bae5f0b243f884c 594 SUPERFAMILY SSF51905 501 565 8.43E-38 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS26160 6822a71791c8225c6bae5f0b243f884c 594 Pfam PF05199 GMC oxidoreductase 498 556 1.2E-9 T 28-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 CU254_RS26160 6822a71791c8225c6bae5f0b243f884c 594 Pfam PF00732 GMC oxidoreductase 3 333 5.9E-12 T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CU254_RS10640 05209a3b704f7ea9c05372f233fe78d4 344 Pfam PF13343 Bacterial extracellular solute-binding protein 83 325 1.8E-31 T 28-03-2018 CU254_RS10640 05209a3b704f7ea9c05372f233fe78d4 344 SUPERFAMILY SSF53850 31 330 3.21E-60 T 28-03-2018 CU254_RS10640 05209a3b704f7ea9c05372f233fe78d4 344 Gene3D G3DSA:3.40.190.10 29 144 1.5E-12 T 28-03-2018 CU254_RS10640 05209a3b704f7ea9c05372f233fe78d4 344 Gene3D G3DSA:3.40.190.10 145 341 8.1E-30 T 28-03-2018 CU254_RS30680 f5c0006718ba6ad0a2ec9e8a2148a37f 129 Gene3D G3DSA:2.60.120.10 1 116 7.7E-18 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS30680 f5c0006718ba6ad0a2ec9e8a2148a37f 129 Pfam PF07883 Cupin domain 40 98 9.3E-9 T 28-03-2018 IPR013096 Cupin 2, conserved barrel CU254_RS30680 f5c0006718ba6ad0a2ec9e8a2148a37f 129 SUPERFAMILY SSF51182 2 113 1.98E-19 T 28-03-2018 IPR011051 RmlC-like cupin domain CU254_RS31910 186c0446c69f8f5a749b33bc42239b1c 442 ProSitePatterns PS00217 Sugar transport proteins signature 2. 124 149 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CU254_RS31910 186c0446c69f8f5a749b33bc42239b1c 442 Gene3D G3DSA:1.20.1250.20 5 221 4.0E-24 T 28-03-2018 CU254_RS31910 186c0446c69f8f5a749b33bc42239b1c 442 SUPERFAMILY SSF103473 10 422 7.85E-67 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS31910 186c0446c69f8f5a749b33bc42239b1c 442 Gene3D G3DSA:1.20.1250.20 222 434 6.0E-31 T 28-03-2018 CU254_RS31910 186c0446c69f8f5a749b33bc42239b1c 442 Pfam PF00083 Sugar (and other) transporter 15 429 4.2E-32 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CU254_RS03595 ec1090e9f4244de626e311ac00aa841e 249 Pfam PF00583 Acetyltransferase (GNAT) family 145 227 1.9E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS03595 ec1090e9f4244de626e311ac00aa841e 249 SUPERFAMILY SSF55729 118 237 4.12E-20 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS03595 ec1090e9f4244de626e311ac00aa841e 249 Gene3D G3DSA:3.40.630.30 49 248 4.1E-21 T 28-03-2018 CU254_RS13595 578f0e94978f45d6544147b37de6bb4c 81 Pfam PF03551 Transcriptional regulator PadR-like family 38 79 5.0E-7 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CU254_RS13595 578f0e94978f45d6544147b37de6bb4c 81 SUPERFAMILY SSF46785 24 79 5.12E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS13595 578f0e94978f45d6544147b37de6bb4c 81 Gene3D G3DSA:1.10.10.10 3 81 3.5E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS24060 871d0923114eac0c71d33df6311342f3 368 Gene3D G3DSA:1.10.3720.10 72 350 8.3E-34 T 28-03-2018 CU254_RS24060 871d0923114eac0c71d33df6311342f3 368 SUPERFAMILY SSF161098 96 348 2.49E-35 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS24060 871d0923114eac0c71d33df6311342f3 368 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 86 355 5.5E-70 T 28-03-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 CU254_RS24060 871d0923114eac0c71d33df6311342f3 368 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 160 355 1.1E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS32255 507f637a7e849c3b27f39a5923797f90 175 Gene3D G3DSA:3.40.630.30 1 140 2.1E-22 T 28-03-2018 CU254_RS32255 507f637a7e849c3b27f39a5923797f90 175 Pfam PF13527 Acetyltransferase (GNAT) domain 2 131 2.2E-8 T 28-03-2018 CU254_RS32255 507f637a7e849c3b27f39a5923797f90 175 SUPERFAMILY SSF55729 1 137 1.25E-23 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS06725 5666cf6d050328828833d40bc432d50d 260 SUPERFAMILY SSF55729 24 230 2.58E-39 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS06725 5666cf6d050328828833d40bc432d50d 260 Gene3D G3DSA:3.40.630.30 25 172 2.7E-35 T 28-03-2018 CU254_RS06725 5666cf6d050328828833d40bc432d50d 260 Pfam PF13444 Acetyltransferase (GNAT) domain 41 142 1.5E-35 T 28-03-2018 CU254_RS19165 ffc75c2d56f326e16eda93c7030bd13f 387 Gene3D G3DSA:1.10.150.130 12 150 9.8E-19 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CU254_RS19165 ffc75c2d56f326e16eda93c7030bd13f 387 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 78 126 1.4E-5 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CU254_RS19165 ffc75c2d56f326e16eda93c7030bd13f 387 Pfam PF00589 Phage integrase family 176 366 8.7E-22 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CU254_RS19165 ffc75c2d56f326e16eda93c7030bd13f 387 SUPERFAMILY SSF56349 79 365 7.65E-34 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CU254_RS19165 ffc75c2d56f326e16eda93c7030bd13f 387 Gene3D G3DSA:1.10.443.10 158 375 1.2E-32 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CU254_RS18600 0cd8347d26831c9022f6b99cccafe681 703 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 5 193 7.9E-44 T 28-03-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403 CU254_RS18600 0cd8347d26831c9022f6b99cccafe681 703 Gene3D G3DSA:3.30.420.40 282 507 0.076 T 28-03-2018 CU254_RS18600 0cd8347d26831c9022f6b99cccafe681 703 Gene3D G3DSA:3.30.1330.10 150 199 0.0087 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CU254_RS18600 0cd8347d26831c9022f6b99cccafe681 703 Pfam PF01968 Hydantoinase/oxoprolinase 214 501 6.3E-81 T 28-03-2018 IPR002821 Hydantoinase/oxoprolinase GO:0016787 Reactome: R-HSA-174403 CU254_RS18600 0cd8347d26831c9022f6b99cccafe681 703 SUPERFAMILY SSF53067 1 59 2.89E-5 T 28-03-2018 CU254_RS18600 0cd8347d26831c9022f6b99cccafe681 703 Gene3D G3DSA:3.30.420.40 1 105 6.4E-7 T 28-03-2018 CU254_RS01950 aacfb2e707f32f78730899c23b0617a6 216 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 8 209 4.0E-89 T 28-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS01950 aacfb2e707f32f78730899c23b0617a6 216 ProSitePatterns PS00474 Ribosomal protein L3 signature. 106 129 - T 28-03-2018 IPR019926 Ribosomal protein L3, conserved site CU254_RS01950 aacfb2e707f32f78730899c23b0617a6 216 Pfam PF00297 Ribosomal protein L3 99 187 7.0E-16 T 28-03-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS01950 aacfb2e707f32f78730899c23b0617a6 216 SUPERFAMILY SSF50447 5 213 8.74E-81 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CU254_RS01950 aacfb2e707f32f78730899c23b0617a6 216 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 6 212 39.685 T 28-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS01950 aacfb2e707f32f78730899c23b0617a6 216 Gene3D G3DSA:4.10.960.10 62 170 1.3E-39 T 28-03-2018 CU254_RS08945 8dbd02283570d7c1de96023e9af17cb0 379 Gene3D G3DSA:3.40.50.2000 144 357 3.2E-51 T 28-03-2018 CU254_RS08945 8dbd02283570d7c1de96023e9af17cb0 379 SUPERFAMILY SSF53756 1 370 7.33E-76 T 28-03-2018 CU254_RS08945 8dbd02283570d7c1de96023e9af17cb0 379 Pfam PF13439 Glycosyltransferase Family 4 9 168 1.1E-10 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CU254_RS08945 8dbd02283570d7c1de96023e9af17cb0 379 Pfam PF00534 Glycosyl transferases group 1 177 352 2.0E-39 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CU254_RS14000 9065c32b0278120dbf9068a6e7a4c2bf 397 Pfam PF01494 FAD binding domain 6 332 6.7E-13 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CU254_RS14000 9065c32b0278120dbf9068a6e7a4c2bf 397 SUPERFAMILY SSF51905 279 368 2.79E-46 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS14000 9065c32b0278120dbf9068a6e7a4c2bf 397 SUPERFAMILY SSF51905 6 170 2.79E-46 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS14000 9065c32b0278120dbf9068a6e7a4c2bf 397 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 292 307 9.5E-19 T 28-03-2018 CU254_RS14000 9065c32b0278120dbf9068a6e7a4c2bf 397 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 9.5E-19 T 28-03-2018 CU254_RS14000 9065c32b0278120dbf9068a6e7a4c2bf 397 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 307 323 9.5E-19 T 28-03-2018 CU254_RS14000 9065c32b0278120dbf9068a6e7a4c2bf 397 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 149 164 9.5E-19 T 28-03-2018 CU254_RS14000 9065c32b0278120dbf9068a6e7a4c2bf 397 Gene3D G3DSA:3.50.50.60 1 397 2.5E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS37400 1bcfb7a08f6c6737032e720b6982701b 187 Hamap MF_00202 Isopentenyl-diphosphate Delta-isomerase [idi]. 10 186 28.312 T 28-03-2018 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 CU254_RS37400 1bcfb7a08f6c6737032e720b6982701b 187 TIGRFAM TIGR02150 IPP_isom_1: isopentenyl-diphosphate delta-isomerase 12 173 1.8E-34 T 28-03-2018 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 CU254_RS37400 1bcfb7a08f6c6737032e720b6982701b 187 SUPERFAMILY SSF55811 10 179 8.67E-38 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CU254_RS37400 1bcfb7a08f6c6737032e720b6982701b 187 Pfam PF00293 NUDIX domain 38 156 3.3E-19 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CU254_RS37400 1bcfb7a08f6c6737032e720b6982701b 187 PIRSF PIRSF018427 1 185 4.6E-46 T 28-03-2018 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 CU254_RS37400 1bcfb7a08f6c6737032e720b6982701b 187 Gene3D G3DSA:3.90.79.10 38 187 1.4E-24 T 28-03-2018 CU254_RS06340 ba0f416b914eded2375b3245c01ad8fb 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 56 9.5E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS06340 ba0f416b914eded2375b3245c01ad8fb 197 Gene3D G3DSA:1.10.10.60 5 58 2.9E-19 T 28-03-2018 CU254_RS06340 ba0f416b914eded2375b3245c01ad8fb 197 Gene3D G3DSA:1.10.357.10 59 190 9.6E-9 T 28-03-2018 CU254_RS06340 ba0f416b914eded2375b3245c01ad8fb 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 54 9.5E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS06340 ba0f416b914eded2375b3245c01ad8fb 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 9.5E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS06340 ba0f416b914eded2375b3245c01ad8fb 197 SUPERFAMILY SSF46689 4 70 2.51E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS25990 2e0c227fdbc9f376f8ada9f22f6499bd 564 Gene3D G3DSA:3.40.50.980 183 330 3.0E-21 T 28-03-2018 CU254_RS25990 2e0c227fdbc9f376f8ada9f22f6499bd 564 Pfam PF00501 AMP-binding enzyme 14 456 8.1E-64 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS25990 2e0c227fdbc9f376f8ada9f22f6499bd 564 ProSitePatterns PS00455 Putative AMP-binding domain signature. 177 188 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS25990 2e0c227fdbc9f376f8ada9f22f6499bd 564 Gene3D G3DSA:3.40.50.980 5 182 2.1E-39 T 28-03-2018 CU254_RS25990 2e0c227fdbc9f376f8ada9f22f6499bd 564 Pfam PF13193 AMP-binding enzyme C-terminal domain 466 538 1.0E-9 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS25990 2e0c227fdbc9f376f8ada9f22f6499bd 564 Gene3D G3DSA:2.30.38.10 372 450 6.5E-18 T 28-03-2018 CU254_RS25990 2e0c227fdbc9f376f8ada9f22f6499bd 564 Gene3D G3DSA:3.30.300.30 452 555 3.3E-21 T 28-03-2018 CU254_RS25990 2e0c227fdbc9f376f8ada9f22f6499bd 564 SUPERFAMILY SSF56801 369 556 5.89E-110 T 28-03-2018 CU254_RS25990 2e0c227fdbc9f376f8ada9f22f6499bd 564 SUPERFAMILY SSF56801 8 334 5.89E-110 T 28-03-2018 CU254_RS29335 09ec97e741be46d7e93b329c4daf877b 253 PRINTS PR00111 Alpha/beta hydrolase fold signature 52 67 2.8E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS29335 09ec97e741be46d7e93b329c4daf877b 253 PRINTS PR00111 Alpha/beta hydrolase fold signature 96 109 2.8E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS29335 09ec97e741be46d7e93b329c4daf877b 253 PRINTS PR00111 Alpha/beta hydrolase fold signature 110 123 2.8E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS29335 09ec97e741be46d7e93b329c4daf877b 253 Gene3D G3DSA:3.40.50.1820 9 251 8.8E-37 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS29335 09ec97e741be46d7e93b329c4daf877b 253 Pfam PF12697 Alpha/beta hydrolase family 28 246 7.4E-19 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS29335 09ec97e741be46d7e93b329c4daf877b 253 SUPERFAMILY SSF53474 7 250 7.71E-42 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS20160 77b80ad89c4ad445da2c3aad2a3b657c 146 SUPERFAMILY SSF55961 6 144 1.78E-23 T 28-03-2018 CU254_RS20160 77b80ad89c4ad445da2c3aad2a3b657c 146 Gene3D G3DSA:3.30.530.20 1 146 1.3E-21 T 28-03-2018 IPR023393 START-like domain CU254_RS20160 77b80ad89c4ad445da2c3aad2a3b657c 146 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 10 127 2.7E-11 T 28-03-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 CU254_RS25200 84f9405bf2bca4c87a83282d9bf765bf 1091 Gene3D G3DSA:2.160.20.10 3 300 2.4E-33 T 28-03-2018 IPR012334 Pectin lyase fold CU254_RS25200 84f9405bf2bca4c87a83282d9bf765bf 1091 Gene3D G3DSA:2.160.20.10 301 501 8.8E-18 T 28-03-2018 IPR012334 Pectin lyase fold CU254_RS25200 84f9405bf2bca4c87a83282d9bf765bf 1091 Pfam PF13229 Right handed beta helix region 101 241 6.0E-8 T 28-03-2018 CU254_RS25200 84f9405bf2bca4c87a83282d9bf765bf 1091 Pfam PF13229 Right handed beta helix region 405 493 1.2E-5 T 28-03-2018 CU254_RS25200 84f9405bf2bca4c87a83282d9bf765bf 1091 SMART SM00382 582 723 7.9E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS25200 84f9405bf2bca4c87a83282d9bf765bf 1091 SUPERFAMILY SSF52540 547 807 1.25E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS25200 84f9405bf2bca4c87a83282d9bf765bf 1091 SMART SM00710 211 231 7700.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CU254_RS25200 84f9405bf2bca4c87a83282d9bf765bf 1091 SMART SM00710 456 478 300.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CU254_RS25200 84f9405bf2bca4c87a83282d9bf765bf 1091 SMART SM00710 257 279 2100.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CU254_RS25200 84f9405bf2bca4c87a83282d9bf765bf 1091 SMART SM00710 371 393 2700.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CU254_RS25200 84f9405bf2bca4c87a83282d9bf765bf 1091 SMART SM00710 119 141 950.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CU254_RS25200 84f9405bf2bca4c87a83282d9bf765bf 1091 SMART SM00710 165 187 120.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CU254_RS25200 84f9405bf2bca4c87a83282d9bf765bf 1091 SMART SM00710 142 164 9000.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CU254_RS25200 84f9405bf2bca4c87a83282d9bf765bf 1091 SMART SM00710 414 436 180.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CU254_RS25200 84f9405bf2bca4c87a83282d9bf765bf 1091 SMART SM00710 280 301 9200.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CU254_RS25200 84f9405bf2bca4c87a83282d9bf765bf 1091 SUPERFAMILY SSF51126 309 494 1.73E-11 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor CU254_RS25200 84f9405bf2bca4c87a83282d9bf765bf 1091 SUPERFAMILY SSF51126 6 230 2.03E-25 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor CU254_RS25200 84f9405bf2bca4c87a83282d9bf765bf 1091 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 587 720 1.5E-16 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CU254_RS25200 84f9405bf2bca4c87a83282d9bf765bf 1091 PRINTS PR00819 CbxX/CfqX superfamily signature 585 600 2.0E-52 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CU254_RS25200 84f9405bf2bca4c87a83282d9bf765bf 1091 PRINTS PR00819 CbxX/CfqX superfamily signature 691 708 2.0E-52 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CU254_RS25200 84f9405bf2bca4c87a83282d9bf765bf 1091 PRINTS PR00819 CbxX/CfqX superfamily signature 765 777 2.0E-52 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CU254_RS25200 84f9405bf2bca4c87a83282d9bf765bf 1091 PRINTS PR00819 CbxX/CfqX superfamily signature 637 656 2.0E-52 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CU254_RS25200 84f9405bf2bca4c87a83282d9bf765bf 1091 PRINTS PR00819 CbxX/CfqX superfamily signature 545 559 2.0E-52 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CU254_RS25200 84f9405bf2bca4c87a83282d9bf765bf 1091 PRINTS PR00819 CbxX/CfqX superfamily signature 623 637 2.0E-52 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CU254_RS25200 84f9405bf2bca4c87a83282d9bf765bf 1091 PRINTS PR00819 CbxX/CfqX superfamily signature 708 727 2.0E-52 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CU254_RS25200 84f9405bf2bca4c87a83282d9bf765bf 1091 PRINTS PR00819 CbxX/CfqX superfamily signature 670 682 2.0E-52 T 28-03-2018 IPR000641 CbxX/CfqX GO:0005524 CU254_RS25200 84f9405bf2bca4c87a83282d9bf765bf 1091 SUPERFAMILY SSF52540 836 1038 1.17E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS25200 84f9405bf2bca4c87a83282d9bf765bf 1091 Gene3D G3DSA:3.40.50.300 527 720 2.3E-25 T 28-03-2018 CU254_RS25200 84f9405bf2bca4c87a83282d9bf765bf 1091 Gene3D G3DSA:3.40.50.300 797 1000 4.5E-6 T 28-03-2018 CU254_RS23560 8d0e3e29c01dba9155c193bd5b674e42 270 Pfam PF04454 Encapsulating protein for peroxidase 2 256 3.9E-78 T 28-03-2018 IPR007544 Encapsulating protein for peroxidase GO:0008233|GO:0042742 CU254_RS23560 8d0e3e29c01dba9155c193bd5b674e42 270 PIRSF PIRSF019254 1 270 1.9E-87 T 28-03-2018 IPR007544 Encapsulating protein for peroxidase GO:0008233|GO:0042742 CU254_RS38290 893a73377d68a2b673334f0676027d94 310 Gene3D G3DSA:3.90.25.10 160 293 3.8E-14 T 28-03-2018 CU254_RS38290 893a73377d68a2b673334f0676027d94 310 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 212 2.0E-16 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CU254_RS38290 893a73377d68a2b673334f0676027d94 310 Gene3D G3DSA:3.40.50.720 1 137 1.6E-16 T 28-03-2018 CU254_RS38290 893a73377d68a2b673334f0676027d94 310 SUPERFAMILY SSF51735 1 285 1.6E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS08995 ce562febcb2f7cd25bfbb0a1871190c9 336 Pfam PF02445 Quinolinate synthetase A protein 24 328 1.3E-111 T 28-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CU254_RS08995 ce562febcb2f7cd25bfbb0a1871190c9 336 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 21 329 2.4E-90 T 28-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CU254_RS08995 ce562febcb2f7cd25bfbb0a1871190c9 336 Gene3D G3DSA:3.40.50.10800 189 311 3.4E-26 T 28-03-2018 CU254_RS08995 ce562febcb2f7cd25bfbb0a1871190c9 336 SUPERFAMILY SSF142754 20 329 1.01E-101 T 28-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CU254_RS08995 ce562febcb2f7cd25bfbb0a1871190c9 336 Gene3D G3DSA:3.40.50.10800 102 188 2.5E-23 T 28-03-2018 CU254_RS08995 ce562febcb2f7cd25bfbb0a1871190c9 336 Gene3D G3DSA:3.40.50.10800 16 98 4.3E-21 T 28-03-2018 CU254_RS10705 04f46d0bf67dcd222a07016168452b6a 289 Gene3D G3DSA:3.40.1190.20 1 289 5.5E-60 T 28-03-2018 IPR029056 Ribokinase-like CU254_RS10705 04f46d0bf67dcd222a07016168452b6a 289 SUPERFAMILY SSF53613 3 289 5.46E-67 T 28-03-2018 IPR029056 Ribokinase-like CU254_RS10705 04f46d0bf67dcd222a07016168452b6a 289 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 37 61 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CU254_RS10705 04f46d0bf67dcd222a07016168452b6a 289 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 245 258 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CU254_RS10705 04f46d0bf67dcd222a07016168452b6a 289 Pfam PF00294 pfkB family carbohydrate kinase 3 288 6.6E-53 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CU254_RS40270 8f08b6702be20de37ade0775539972bb 469 SUPERFAMILY SSF56801 22 466 7.33E-76 T 28-03-2018 CU254_RS40270 8f08b6702be20de37ade0775539972bb 469 Gene3D G3DSA:3.30.300.30 370 469 2.8E-9 T 28-03-2018 CU254_RS40270 8f08b6702be20de37ade0775539972bb 469 Pfam PF00501 AMP-binding enzyme 16 374 3.1E-53 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS40270 8f08b6702be20de37ade0775539972bb 469 Gene3D G3DSA:3.40.50.980 134 285 2.7E-32 T 28-03-2018 CU254_RS40270 8f08b6702be20de37ade0775539972bb 469 Gene3D G3DSA:2.30.38.10 286 369 3.4E-16 T 28-03-2018 CU254_RS40270 8f08b6702be20de37ade0775539972bb 469 ProSitePatterns PS00455 Putative AMP-binding domain signature. 127 138 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS40270 8f08b6702be20de37ade0775539972bb 469 Gene3D G3DSA:3.40.50.980 5 133 5.3E-9 T 28-03-2018 CU254_RS41365 28015d883dab9062d4c21c2326a51919 460 Gene3D G3DSA:1.10.260.40 25 100 4.1E-14 T 28-03-2018 CU254_RS41365 28015d883dab9062d4c21c2326a51919 460 SMART SM00530 26 81 9.4E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS41365 28015d883dab9062d4c21c2326a51919 460 SUPERFAMILY SSF47413 26 82 1.21E-11 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS41365 28015d883dab9062d4c21c2326a51919 460 Pfam PF01381 Helix-turn-helix 27 81 6.4E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS41365 28015d883dab9062d4c21c2326a51919 460 Gene3D G3DSA:1.25.40.10 247 440 3.4E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS06215 0d2981e7872efd3ab9a069e4eb62fe96 391 Gene3D G3DSA:1.20.1250.20 3 190 4.4E-24 T 28-03-2018 CU254_RS06215 0d2981e7872efd3ab9a069e4eb62fe96 391 Gene3D G3DSA:1.20.1250.20 191 375 1.2E-17 T 28-03-2018 CU254_RS06215 0d2981e7872efd3ab9a069e4eb62fe96 391 Pfam PF07690 Major Facilitator Superfamily 9 234 2.0E-27 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS06215 0d2981e7872efd3ab9a069e4eb62fe96 391 SUPERFAMILY SSF103473 4 373 2.75E-49 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS10255 0d23eea0894069196172da6b0c611b59 203 Gene3D G3DSA:3.40.50.300 9 196 4.0E-18 T 28-03-2018 CU254_RS10255 0d23eea0894069196172da6b0c611b59 203 Pfam PF03029 Conserved hypothetical ATP binding protein 24 191 3.5E-25 T 28-03-2018 IPR004130 GPN-loop GTPase CU254_RS10255 0d23eea0894069196172da6b0c611b59 203 SUPERFAMILY SSF52540 20 192 3.43E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS08130 ed689f23732505a5d2e2aef6e6403430 317 Pfam PF03060 Nitronate monooxygenase 83 316 2.6E-42 T 28-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CU254_RS08130 ed689f23732505a5d2e2aef6e6403430 317 Pfam PF03060 Nitronate monooxygenase 10 76 8.6E-16 T 28-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CU254_RS08130 ed689f23732505a5d2e2aef6e6403430 317 Gene3D G3DSA:3.20.20.70 5 317 1.6E-45 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS08130 ed689f23732505a5d2e2aef6e6403430 317 SUPERFAMILY SSF51412 7 313 3.36E-52 T 28-03-2018 CU254_RS20745 321ffd23efee5f822033d223fe3ec2ec 305 TIGRFAM TIGR02039 CysD: sulfate adenylyltransferase, small subunit 15 305 1.2E-137 T 28-03-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 CU254_RS20745 321ffd23efee5f822033d223fe3ec2ec 305 Gene3D G3DSA:3.40.50.620 6 302 3.1E-42 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS20745 321ffd23efee5f822033d223fe3ec2ec 305 PIRSF PIRSF002936 5 305 5.1E-137 T 28-03-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 CU254_RS20745 321ffd23efee5f822033d223fe3ec2ec 305 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 35 258 1.3E-49 T 28-03-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 CU254_RS20745 321ffd23efee5f822033d223fe3ec2ec 305 SUPERFAMILY SSF52402 10 213 1.94E-66 T 28-03-2018 CU254_RS39090 8809b6a0a31d63c074a8d02efc57f351 190 Gene3D G3DSA:3.40.1740.10 2 89 9.4E-18 T 28-03-2018 CU254_RS39090 8809b6a0a31d63c074a8d02efc57f351 190 Gene3D G3DSA:3.40.1740.10 107 178 7.0E-11 T 28-03-2018 CU254_RS39090 8809b6a0a31d63c074a8d02efc57f351 190 Pfam PF02622 Uncharacterized ACR, COG1678 17 174 6.0E-37 T 28-03-2018 IPR003774 Protein of unknown function UPF0301 CU254_RS39090 8809b6a0a31d63c074a8d02efc57f351 190 Hamap MF_00758 UPF0301 protein YqgE [yqgE]. 6 187 26.107 T 28-03-2018 IPR003774 Protein of unknown function UPF0301 CU254_RS39090 8809b6a0a31d63c074a8d02efc57f351 190 SUPERFAMILY SSF143456 7 185 2.75E-49 T 28-03-2018 CU254_RS21805 b98ef3a72b7597107bfd9d617208ea7f 334 SUPERFAMILY SSF51679 3 331 1.1E-73 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS21805 b98ef3a72b7597107bfd9d617208ea7f 334 TIGRFAM TIGR03554 F420_G6P_DH: glucose-6-phosphate dehydrogenase (coenzyme-F420) 2 331 7.6E-179 T 28-03-2018 IPR019944 F420-dependent glucose-6-phosphate dehydrogenase CU254_RS21805 b98ef3a72b7597107bfd9d617208ea7f 334 TIGRFAM TIGR03557 F420_G6P_family: F420-dependent oxidoreductase, G6PDH family 5 331 6.3E-80 T 28-03-2018 IPR019945 F420-dependent glucose-6-phosphate dehydrogenase-related CU254_RS21805 b98ef3a72b7597107bfd9d617208ea7f 334 Hamap MF_02123 F420-dependent glucose-6-phosphate dehydrogenase [fgd]. 2 333 68.693 T 28-03-2018 IPR019944 F420-dependent glucose-6-phosphate dehydrogenase CU254_RS21805 b98ef3a72b7597107bfd9d617208ea7f 334 Gene3D G3DSA:3.20.20.30 2 333 2.0E-76 T 28-03-2018 CU254_RS21805 b98ef3a72b7597107bfd9d617208ea7f 334 Pfam PF00296 Luciferase-like monooxygenase 11 305 1.1E-65 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS35335 fa10c74feb77e3cb7ca6ccd10814c276 894 Pfam PF08376 Nitrate and nitrite sensing 82 321 1.3E-34 T 28-03-2018 IPR013587 Nitrate/nitrite sensing protein CU254_RS35335 fa10c74feb77e3cb7ca6ccd10814c276 894 Pfam PF00672 HAMP domain 359 431 5.2E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS35335 fa10c74feb77e3cb7ca6ccd10814c276 894 SMART SM00387 546 657 2.6E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS35335 fa10c74feb77e3cb7ca6ccd10814c276 894 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 549 655 3.3E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS35335 fa10c74feb77e3cb7ca6ccd10814c276 894 Gene3D G3DSA:3.30.565.10 437 656 4.4E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS35335 fa10c74feb77e3cb7ca6ccd10814c276 894 SUPERFAMILY SSF55874 540 654 1.27E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS35335 fa10c74feb77e3cb7ca6ccd10814c276 894 SMART SM00304 359 434 0.0038 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS09585 3880e537cfdafd0a2333fef5a139c299 186 Pfam PF02441 Flavoprotein 9 150 8.5E-16 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CU254_RS09585 3880e537cfdafd0a2333fef5a139c299 186 SUPERFAMILY SSF52507 6 167 1.83E-18 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CU254_RS09585 3880e537cfdafd0a2333fef5a139c299 186 Gene3D G3DSA:3.40.50.1950 1 186 5.8E-24 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CU254_RS14530 135d95415ff5ddb87b884629147dc0fb 246 Gene3D G3DSA:1.10.10.10 1 67 8.9E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS14530 135d95415ff5ddb87b884629147dc0fb 246 Gene3D G3DSA:3.30.450.40 70 245 7.8E-37 T 28-03-2018 IPR029016 GAF domain-like CU254_RS14530 135d95415ff5ddb87b884629147dc0fb 246 Pfam PF09339 IclR helix-turn-helix domain 12 58 2.5E-10 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS14530 135d95415ff5ddb87b884629147dc0fb 246 SUPERFAMILY SSF55781 64 236 1.11E-33 T 28-03-2018 IPR029016 GAF domain-like CU254_RS14530 135d95415ff5ddb87b884629147dc0fb 246 Pfam PF01614 Bacterial transcriptional regulator 128 220 1.1E-13 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal CU254_RS14530 135d95415ff5ddb87b884629147dc0fb 246 SUPERFAMILY SSF46785 11 71 3.76E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS14530 135d95415ff5ddb87b884629147dc0fb 246 SMART SM00346 9 94 2.8E-9 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS21855 c5b65a874a1b79136e2b8093285ed107 498 Pfam PF13556 PucR C-terminal helix-turn-helix domain 432 490 6.0E-20 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CU254_RS21855 c5b65a874a1b79136e2b8093285ed107 498 Gene3D G3DSA:1.10.10.60 418 469 1.8E-4 T 28-03-2018 CU254_RS29930 a2f3eb5efe9c2c9d2f6f32fa53e4e9b2 221 Pfam PF02698 DUF218 domain 41 150 3.2E-19 T 28-03-2018 IPR003848 Domain of unknown function DUF218 CU254_RS29930 a2f3eb5efe9c2c9d2f6f32fa53e4e9b2 221 Gene3D G3DSA:3.40.50.620 23 161 1.0E-25 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS20440 c205dc7799906fb3ade86f42a4e31a11 271 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 96 265 1.4E-27 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS20440 c205dc7799906fb3ade86f42a4e31a11 271 Gene3D G3DSA:1.10.3720.10 26 270 5.2E-29 T 28-03-2018 CU254_RS20440 c205dc7799906fb3ade86f42a4e31a11 271 SUPERFAMILY SSF161098 72 253 6.28E-34 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS28635 54f26c7f48a73a0f3100b2c42655dd5a 266 Pfam PF08241 Methyltransferase domain 107 203 8.3E-18 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CU254_RS28635 54f26c7f48a73a0f3100b2c42655dd5a 266 Gene3D G3DSA:3.40.50.150 64 264 3.1E-30 T 28-03-2018 CU254_RS28635 54f26c7f48a73a0f3100b2c42655dd5a 266 SUPERFAMILY SSF53335 78 253 4.8E-31 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS27790 52f3ca1e0ca0813fd60a3c9ff2447f3e 374 Pfam PF02515 CoA-transferase family III 3 362 2.0E-114 T 28-03-2018 IPR003673 CoA-transferase family III GO:0003824 CU254_RS27790 52f3ca1e0ca0813fd60a3c9ff2447f3e 374 Gene3D G3DSA:3.40.50.10540 1 374 2.9E-125 T 28-03-2018 IPR023606 CoA-transferase family III domain CU254_RS27790 52f3ca1e0ca0813fd60a3c9ff2447f3e 374 SUPERFAMILY SSF89796 2 369 1.31E-118 T 28-03-2018 IPR023606 CoA-transferase family III domain CU254_RS30015 001ba55154bbcd9450a069f2df10d0d7 210 Gene3D G3DSA:1.10.10.60 48 182 8.8E-12 T 28-03-2018 CU254_RS30015 001ba55154bbcd9450a069f2df10d0d7 210 SUPERFAMILY SSF48498 77 201 2.99E-27 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS30015 001ba55154bbcd9450a069f2df10d0d7 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 60 2.0E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS30015 001ba55154bbcd9450a069f2df10d0d7 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 1.2E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS30015 001ba55154bbcd9450a069f2df10d0d7 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 1.2E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS30015 001ba55154bbcd9450a069f2df10d0d7 210 Gene3D G3DSA:1.10.10.60 2 47 8.3E-20 T 28-03-2018 CU254_RS30015 001ba55154bbcd9450a069f2df10d0d7 210 SUPERFAMILY SSF46689 3 65 2.41E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS30015 001ba55154bbcd9450a069f2df10d0d7 210 ProSitePatterns PS01081 TetR-type HTH domain signature. 26 56 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CU254_RS10695 32ad2b90a46d412f037697c7b3b91337 430 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 29 389 1.1E-83 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CU254_RS10695 32ad2b90a46d412f037697c7b3b91337 430 SUPERFAMILY SSF53187 11 215 6.28E-72 T 28-03-2018 CU254_RS10695 32ad2b90a46d412f037697c7b3b91337 430 SUPERFAMILY SSF53187 318 421 6.28E-72 T 28-03-2018 CU254_RS10695 32ad2b90a46d412f037697c7b3b91337 430 Pfam PF07687 Peptidase dimerisation domain 203 299 1.2E-9 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CU254_RS10695 32ad2b90a46d412f037697c7b3b91337 430 PIRSF PIRSF005962 7 424 3.2E-98 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CU254_RS10695 32ad2b90a46d412f037697c7b3b91337 430 Gene3D G3DSA:3.40.630.10 1 299 4.9E-60 T 28-03-2018 CU254_RS10695 32ad2b90a46d412f037697c7b3b91337 430 Pfam PF01546 Peptidase family M20/M25/M40 80 371 9.7E-22 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CU254_RS10695 32ad2b90a46d412f037697c7b3b91337 430 SUPERFAMILY SSF55031 202 303 2.36E-27 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CU254_RS00230 aa9bc253e9d0ceca8dc2d4579d820890 208 Gene3D G3DSA:3.40.50.720 2 208 2.9E-21 T 28-03-2018 CU254_RS00230 aa9bc253e9d0ceca8dc2d4579d820890 208 SUPERFAMILY SSF51735 3 207 7.43E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS00230 aa9bc253e9d0ceca8dc2d4579d820890 208 Pfam PF13460 NAD(P)H-binding 9 197 3.2E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS39305 5077e8a854f19ad77d8a33fcfdabb93b 76 SUPERFAMILY SSF54427 3 69 2.1E-12 T 28-03-2018 IPR032710 NTF2-like domain CU254_RS39305 5077e8a854f19ad77d8a33fcfdabb93b 76 Pfam PF07366 SnoaL-like polyketide cyclase 3 65 2.9E-10 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CU254_RS39305 5077e8a854f19ad77d8a33fcfdabb93b 76 Gene3D G3DSA:3.10.450.50 2 68 5.0E-10 T 28-03-2018 CU254_RS21425 8214e7f56149678ce1fe6a897f0d4342 261 Gene3D G3DSA:3.20.10.10 107 256 1.4E-30 T 28-03-2018 CU254_RS21425 8214e7f56149678ce1fe6a897f0d4342 261 Pfam PF01063 Amino-transferase class IV 25 234 1.8E-34 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CU254_RS21425 8214e7f56149678ce1fe6a897f0d4342 261 Gene3D G3DSA:3.30.470.10 12 97 1.1E-11 T 28-03-2018 CU254_RS21425 8214e7f56149678ce1fe6a897f0d4342 261 SUPERFAMILY SSF56752 21 242 8.89E-42 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CU254_RS03230 e164feead526c6885199772068398dc2 437 SUPERFAMILY SSF118215 4 408 1.01E-87 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CU254_RS03230 e164feead526c6885199772068398dc2 437 PRINTS PR00173 Glutamate-aspartate symporter signature 357 377 9.2E-24 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CU254_RS03230 e164feead526c6885199772068398dc2 437 PRINTS PR00173 Glutamate-aspartate symporter signature 42 62 9.2E-24 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CU254_RS03230 e164feead526c6885199772068398dc2 437 PRINTS PR00173 Glutamate-aspartate symporter signature 296 322 9.2E-24 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CU254_RS03230 e164feead526c6885199772068398dc2 437 PRINTS PR00173 Glutamate-aspartate symporter signature 331 350 9.2E-24 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CU254_RS03230 e164feead526c6885199772068398dc2 437 PRINTS PR00173 Glutamate-aspartate symporter signature 75 100 9.2E-24 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CU254_RS03230 e164feead526c6885199772068398dc2 437 PRINTS PR00173 Glutamate-aspartate symporter signature 229 248 9.2E-24 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CU254_RS03230 e164feead526c6885199772068398dc2 437 PRINTS PR00173 Glutamate-aspartate symporter signature 194 213 9.2E-24 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CU254_RS03230 e164feead526c6885199772068398dc2 437 Pfam PF00375 Sodium:dicarboxylate symporter family 4 406 4.9E-93 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CU254_RS03230 e164feead526c6885199772068398dc2 437 Gene3D G3DSA:1.10.3860.10 1 414 2.9E-93 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CU254_RS32000 b21e6eb0196c397c9646aef1e62663d0 487 Gene3D G3DSA:3.40.605.10 11 277 3.2E-95 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CU254_RS32000 b21e6eb0196c397c9646aef1e62663d0 487 Gene3D G3DSA:3.40.309.10 278 469 2.2E-72 T 28-03-2018 CU254_RS32000 b21e6eb0196c397c9646aef1e62663d0 487 Pfam PF00171 Aldehyde dehydrogenase family 23 482 1.1E-165 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CU254_RS32000 b21e6eb0196c397c9646aef1e62663d0 487 SUPERFAMILY SSF53720 16 485 1.44E-166 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CU254_RS32000 b21e6eb0196c397c9646aef1e62663d0 487 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 259 266 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CU254_RS07850 bb1094ee7d10938c568400823d0d9385 442 Gene3D G3DSA:3.20.20.140 69 413 2.5E-113 T 28-03-2018 CU254_RS07850 bb1094ee7d10938c568400823d0d9385 442 SUPERFAMILY SSF51338 1 53 1.21E-20 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS07850 bb1094ee7d10938c568400823d0d9385 442 SUPERFAMILY SSF51338 373 430 1.21E-20 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS07850 bb1094ee7d10938c568400823d0d9385 442 SUPERFAMILY SSF51556 55 373 2.27E-97 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS07850 bb1094ee7d10938c568400823d0d9385 442 Pfam PF01979 Amidohydrolase family 51 425 5.1E-32 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CU254_RS07850 bb1094ee7d10938c568400823d0d9385 442 TIGRFAM TIGR03178 allantoinase: allantoinase 2 432 2.2E-169 T 28-03-2018 IPR017593 Allantoinase GO:0000256|GO:0004038|GO:0008270|GO:0050897 KEGG: 00230+3.5.2.5|MetaCyc: PWY-5697|MetaCyc: PWY-5698 CU254_RS07850 bb1094ee7d10938c568400823d0d9385 442 Gene3D G3DSA:2.30.40.10 1 68 1.8E-18 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS30170 56c2a87604b691501ab0fb70e0e2d409 493 Gene3D G3DSA:3.40.50.980 157 305 2.7E-32 T 28-03-2018 CU254_RS30170 56c2a87604b691501ab0fb70e0e2d409 493 Pfam PF13193 AMP-binding enzyme C-terminal domain 410 478 1.9E-5 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS30170 56c2a87604b691501ab0fb70e0e2d409 493 Gene3D G3DSA:3.30.300.30 396 493 4.5E-13 T 28-03-2018 CU254_RS30170 56c2a87604b691501ab0fb70e0e2d409 493 Gene3D G3DSA:2.30.38.10 306 394 1.9E-26 T 28-03-2018 CU254_RS30170 56c2a87604b691501ab0fb70e0e2d409 493 Pfam PF00501 AMP-binding enzyme 20 401 1.7E-81 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS30170 56c2a87604b691501ab0fb70e0e2d409 493 SUPERFAMILY SSF56801 14 488 1.7E-116 T 28-03-2018 CU254_RS30170 56c2a87604b691501ab0fb70e0e2d409 493 Gene3D G3DSA:3.40.50.980 11 156 4.1E-32 T 28-03-2018 CU254_RS10755 f0e5c635824df303836099349b9da5a5 378 Gene3D G3DSA:3.30.420.40 67 191 1.7E-25 T 28-03-2018 CU254_RS10755 f0e5c635824df303836099349b9da5a5 378 SUPERFAMILY SSF53067 75 374 6.48E-41 T 28-03-2018 CU254_RS10755 f0e5c635824df303836099349b9da5a5 378 Pfam PF00480 ROK family 76 370 5.4E-47 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CU254_RS10755 f0e5c635824df303836099349b9da5a5 378 SUPERFAMILY SSF46785 1 65 3.58E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS10755 f0e5c635824df303836099349b9da5a5 378 Gene3D G3DSA:1.10.10.10 1 66 1.5E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS10755 f0e5c635824df303836099349b9da5a5 378 Gene3D G3DSA:3.30.420.40 192 378 1.2E-41 T 28-03-2018 CU254_RS02000 b86c265ef0e347983f58eb085b80e6a5 122 SUPERFAMILY SSF50193 2 122 4.32E-50 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CU254_RS02000 b86c265ef0e347983f58eb085b80e6a5 122 Gene3D G3DSA:2.40.150.20 1 122 1.1E-52 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CU254_RS02000 b86c265ef0e347983f58eb085b80e6a5 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 28-03-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS02000 b86c265ef0e347983f58eb085b80e6a5 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 27.009 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CU254_RS02000 b86c265ef0e347983f58eb085b80e6a5 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 1.1E-56 T 28-03-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 CU254_RS02000 b86c265ef0e347983f58eb085b80e6a5 122 SMART SM01374 1 122 5.3E-86 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CU254_RS02000 b86c265ef0e347983f58eb085b80e6a5 122 Pfam PF00238 Ribosomal protein L14p/L23e 2 122 5.0E-54 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CU254_RS36885 5e854de23d315f5e86e381a682e141c4 182 Pfam PF03358 NADPH-dependent FMN reductase 1 139 9.7E-24 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CU254_RS36885 5e854de23d315f5e86e381a682e141c4 182 Gene3D G3DSA:3.40.50.360 1 182 5.1E-27 T 28-03-2018 IPR029039 Flavoprotein-like domain CU254_RS36885 5e854de23d315f5e86e381a682e141c4 182 SUPERFAMILY SSF52218 1 174 1.1E-32 T 28-03-2018 IPR029039 Flavoprotein-like domain CU254_RS02560 12adbf1082909156d848a5c573f661ae 144 Pfam PF08044 Domain of unknown function (DUF1707) 9 61 2.0E-17 T 28-03-2018 IPR012551 Protein of unknown function DUF1707 CU254_RS09160 3c398bfd01a87c18b64359bcc1803a00 217 Pfam PF00072 Response regulator receiver domain 17 124 1.3E-12 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS09160 3c398bfd01a87c18b64359bcc1803a00 217 SMART SM00421 153 210 1.4E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS09160 3c398bfd01a87c18b64359bcc1803a00 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 3.9E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS09160 3c398bfd01a87c18b64359bcc1803a00 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 3.9E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS09160 3c398bfd01a87c18b64359bcc1803a00 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 3.9E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS09160 3c398bfd01a87c18b64359bcc1803a00 217 Gene3D G3DSA:3.40.50.2300 1 126 1.7E-17 T 28-03-2018 CU254_RS09160 3c398bfd01a87c18b64359bcc1803a00 217 SUPERFAMILY SSF52172 12 140 1.99E-16 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS09160 3c398bfd01a87c18b64359bcc1803a00 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 209 1.1E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS09160 3c398bfd01a87c18b64359bcc1803a00 217 SMART SM00448 13 123 2.2E-9 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS09160 3c398bfd01a87c18b64359bcc1803a00 217 Gene3D G3DSA:1.10.10.10 127 217 5.7E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS09160 3c398bfd01a87c18b64359bcc1803a00 217 SUPERFAMILY SSF46894 146 216 2.04E-16 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS01085 00824fe874225b82b4f2f6d30e6e5726 33 SMART SM01155 1 33 1.6E-7 T 28-03-2018 IPR013177 Domain of unknown function DUF1713 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS01085 00824fe874225b82b4f2f6d30e6e5726 33 Pfam PF08213 Mitochondrial domain of unknown function (DUF1713) 1 33 1.6E-11 T 28-03-2018 IPR013177 Domain of unknown function DUF1713 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS10020 2061b63760e80695658eb76c8a788e66 136 SUPERFAMILY SSF55961 11 113 2.1E-7 T 28-03-2018 CU254_RS10020 2061b63760e80695658eb76c8a788e66 136 Gene3D G3DSA:3.30.530.20 55 123 6.7E-4 T 28-03-2018 IPR023393 START-like domain CU254_RS10020 2061b63760e80695658eb76c8a788e66 136 Gene3D G3DSA:3.30.530.20 6 54 2.5E-6 T 28-03-2018 IPR023393 START-like domain CU254_RS24290 0ede0314ee9e8eb17d75c223cc82fea3 411 SUPERFAMILY SSF51905 268 362 7.48E-54 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS24290 0ede0314ee9e8eb17d75c223cc82fea3 411 SUPERFAMILY SSF51905 5 176 7.48E-54 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS24290 0ede0314ee9e8eb17d75c223cc82fea3 411 Pfam PF01494 FAD binding domain 6 332 7.6E-51 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CU254_RS24290 0ede0314ee9e8eb17d75c223cc82fea3 411 Gene3D G3DSA:3.50.50.60 2 385 7.0E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS24290 0ede0314ee9e8eb17d75c223cc82fea3 411 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 155 170 3.6E-19 T 28-03-2018 CU254_RS24290 0ede0314ee9e8eb17d75c223cc82fea3 411 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 281 296 3.6E-19 T 28-03-2018 CU254_RS24290 0ede0314ee9e8eb17d75c223cc82fea3 411 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 296 312 3.6E-19 T 28-03-2018 CU254_RS24290 0ede0314ee9e8eb17d75c223cc82fea3 411 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 3.6E-19 T 28-03-2018 CU254_RS27365 e33921b3a23b032297057d7c4534ce68 306 TIGRFAM TIGR02960 SigX5: RNA polymerase sigma-70 factor, TIGR02960 family 9 301 5.1E-98 T 28-03-2018 IPR014305 RNA polymerase sigma-G type, actinobacteria CU254_RS27365 e33921b3a23b032297057d7c4534ce68 306 SUPERFAMILY SSF88659 119 175 1.31E-10 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS27365 e33921b3a23b032297057d7c4534ce68 306 Pfam PF12680 SnoaL-like domain 195 286 1.5E-10 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CU254_RS27365 e33921b3a23b032297057d7c4534ce68 306 Gene3D G3DSA:1.10.10.10 123 163 7.1E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS27365 e33921b3a23b032297057d7c4534ce68 306 Pfam PF08281 Sigma-70, region 4 122 173 4.0E-12 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS27365 e33921b3a23b032297057d7c4534ce68 306 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 30 62 - T 28-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS27365 e33921b3a23b032297057d7c4534ce68 306 SUPERFAMILY SSF88946 9 79 5.1E-23 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS27365 e33921b3a23b032297057d7c4534ce68 306 SUPERFAMILY SSF54427 187 301 8.98E-21 T 28-03-2018 IPR032710 NTF2-like domain CU254_RS27365 e33921b3a23b032297057d7c4534ce68 306 Gene3D G3DSA:1.10.1740.10 6 79 2.6E-22 T 28-03-2018 CU254_RS27365 e33921b3a23b032297057d7c4534ce68 306 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 10 174 8.3E-19 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS27365 e33921b3a23b032297057d7c4534ce68 306 Pfam PF04542 Sigma-70 region 2 9 76 1.4E-22 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS27365 e33921b3a23b032297057d7c4534ce68 306 Gene3D G3DSA:3.10.450.50 164 304 9.2E-25 T 28-03-2018 CU254_RS04945 43aba142c29e33a545b95e4daedbc507 388 Gene3D G3DSA:3.50.50.60 1 386 4.1E-33 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS04945 43aba142c29e33a545b95e4daedbc507 388 Pfam PF01494 FAD binding domain 306 366 5.5E-10 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CU254_RS04945 43aba142c29e33a545b95e4daedbc507 388 SUPERFAMILY SSF51905 294 381 1.22E-44 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS04945 43aba142c29e33a545b95e4daedbc507 388 SUPERFAMILY SSF51905 1 163 1.22E-44 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS29360 edc6e1131d9f7e8ecd50d037c54ee930 387 Pfam PF00155 Aminotransferase class I and II 39 376 3.9E-66 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CU254_RS29360 edc6e1131d9f7e8ecd50d037c54ee930 387 Gene3D G3DSA:3.40.640.10 46 278 3.5E-54 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS29360 edc6e1131d9f7e8ecd50d037c54ee930 387 SUPERFAMILY SSF53383 9 381 2.53E-107 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS29360 edc6e1131d9f7e8ecd50d037c54ee930 387 Gene3D G3DSA:3.90.1150.10 279 387 1.3E-27 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS29360 edc6e1131d9f7e8ecd50d037c54ee930 387 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 231 240 - T 28-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 CU254_RS42070 426d929f62d0feb24262b4234383cebd 411 Gene3D G3DSA:3.40.640.10 39 261 3.4E-40 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS42070 426d929f62d0feb24262b4234383cebd 411 SUPERFAMILY SSF53383 5 361 1.39E-71 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS42070 426d929f62d0feb24262b4234383cebd 411 Gene3D G3DSA:3.90.1150.10 262 407 1.4E-13 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS42070 426d929f62d0feb24262b4234383cebd 411 Pfam PF00155 Aminotransferase class I and II 46 361 2.0E-44 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CU254_RS42070 426d929f62d0feb24262b4234383cebd 411 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 221 234 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CU254_RS33145 d02e475ccb513d97faff3e51fe0930a2 386 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 146 161 3.2E-13 T 28-03-2018 CU254_RS33145 d02e475ccb513d97faff3e51fe0930a2 386 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 3.2E-13 T 28-03-2018 CU254_RS33145 d02e475ccb513d97faff3e51fe0930a2 386 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 285 300 3.2E-13 T 28-03-2018 CU254_RS33145 d02e475ccb513d97faff3e51fe0930a2 386 SUPERFAMILY SSF51905 3 167 1.69E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS33145 d02e475ccb513d97faff3e51fe0930a2 386 SUPERFAMILY SSF51905 271 357 1.69E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS33145 d02e475ccb513d97faff3e51fe0930a2 386 Gene3D G3DSA:3.50.50.60 1 382 1.8E-37 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS33145 d02e475ccb513d97faff3e51fe0930a2 386 Pfam PF01494 FAD binding domain 3 46 5.9E-5 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CU254_RS40550 f3e0ce9e1f8df391eaffa7cc6902efa4 186 SUPERFAMILY SSF81324 29 184 2.65E-5 T 28-03-2018 CU254_RS40550 f3e0ce9e1f8df391eaffa7cc6902efa4 186 Pfam PF07077 Protein of unknown function (DUF1345) 15 178 4.5E-9 T 28-03-2018 IPR009781 Protein of unknown function DUF1345 CU254_RS40550 f3e0ce9e1f8df391eaffa7cc6902efa4 186 Gene3D G3DSA:1.10.287.70 31 186 8.4E-7 T 28-03-2018 CU254_RS12325 0ee6fb077eff2686cf32d6de7bbc9a83 486 Pfam PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal 4 268 3.0E-92 T 28-03-2018 IPR024674 HpaB/PvcC/4-BUDH N-terminal CU254_RS12325 0ee6fb077eff2686cf32d6de7bbc9a83 486 Gene3D G3DSA:1.10.3140.10 1 140 4.2E-41 T 28-03-2018 CU254_RS12325 0ee6fb077eff2686cf32d6de7bbc9a83 486 Gene3D G3DSA:2.40.110.10 141 270 6.1E-17 T 28-03-2018 CU254_RS12325 0ee6fb077eff2686cf32d6de7bbc9a83 486 SUPERFAMILY SSF56645 1 269 4.71E-74 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS12325 0ee6fb077eff2686cf32d6de7bbc9a83 486 PIRSF PIRSF000331 1 483 2.9E-139 T 28-03-2018 IPR004925 HpaB/PvcC/4-BUDH CU254_RS12325 0ee6fb077eff2686cf32d6de7bbc9a83 486 SUPERFAMILY SSF47203 259 476 9.63E-59 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS12325 0ee6fb077eff2686cf32d6de7bbc9a83 486 Pfam PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal 277 475 7.5E-66 T 28-03-2018 IPR024719 HpaB/PvcC/4-BUDH C-terminal CU254_RS12325 0ee6fb077eff2686cf32d6de7bbc9a83 486 Gene3D G3DSA:1.20.140.10 279 476 1.5E-65 T 28-03-2018 CU254_RS24130 eb83348dfaf46c07129cca448b00f2b8 302 Gene3D G3DSA:1.10.10.10 1 82 8.2E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS24130 eb83348dfaf46c07129cca448b00f2b8 302 Gene3D G3DSA:3.40.190.10 178 267 2.9E-23 T 28-03-2018 CU254_RS24130 eb83348dfaf46c07129cca448b00f2b8 302 Pfam PF03466 LysR substrate binding domain 87 290 1.6E-39 T 28-03-2018 IPR005119 LysR, substrate-binding CU254_RS24130 eb83348dfaf46c07129cca448b00f2b8 302 SUPERFAMILY SSF53850 88 292 4.96E-33 T 28-03-2018 CU254_RS24130 eb83348dfaf46c07129cca448b00f2b8 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.7E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS24130 eb83348dfaf46c07129cca448b00f2b8 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.7E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS24130 eb83348dfaf46c07129cca448b00f2b8 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.7E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS24130 eb83348dfaf46c07129cca448b00f2b8 302 SUPERFAMILY SSF46785 1 85 6.95E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS24130 eb83348dfaf46c07129cca448b00f2b8 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 5.6E-24 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS24130 eb83348dfaf46c07129cca448b00f2b8 302 Gene3D G3DSA:3.40.190.10 88 177 2.7E-18 T 28-03-2018 CU254_RS25830 f47486e34625574a0b7e3d3646897fab 145 ProSitePatterns PS00234 Gas vesicles protein GVPa signature 1. 23 37 - T 28-03-2018 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 CU254_RS25830 f47486e34625574a0b7e3d3646897fab 145 Hamap MF_00576 Gas vesicle structural protein [gvpA]. 11 98 26.848 T 28-03-2018 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 CU254_RS25830 f47486e34625574a0b7e3d3646897fab 145 Pfam PF00741 Gas vesicle protein 22 60 3.0E-14 T 28-03-2018 IPR000638 Gas vesicle protein GvpA GO:0005198|GO:0012506 CU254_RS25830 f47486e34625574a0b7e3d3646897fab 145 ProSitePatterns PS00669 Gas vesicles protein GVPa signature 2. 56 69 - T 28-03-2018 IPR018493 Gas vesicle protein GvpA, conserved site GO:0005198|GO:0012506 CU254_RS10060 4dd7ead0020bb9aeb0ccd3c510db0e1c 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 61 1.2E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS10060 4dd7ead0020bb9aeb0ccd3c510db0e1c 188 SUPERFAMILY SSF46689 7 77 1.35E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS10060 4dd7ead0020bb9aeb0ccd3c510db0e1c 188 Gene3D G3DSA:1.10.357.10 1 184 1.4E-27 T 28-03-2018 CU254_RS33115 353059a8fb8057222c393c5a30864758 421 SUPERFAMILY SSF53850 23 420 2.07E-47 T 28-03-2018 CU254_RS33115 353059a8fb8057222c393c5a30864758 421 Gene3D G3DSA:3.40.190.10 30 183 7.4E-23 T 28-03-2018 CU254_RS33115 353059a8fb8057222c393c5a30864758 421 Pfam PF13416 Bacterial extracellular solute-binding protein 49 353 3.1E-28 T 28-03-2018 CU254_RS33115 353059a8fb8057222c393c5a30864758 421 Gene3D G3DSA:3.40.190.10 184 378 3.4E-18 T 28-03-2018 CU254_RS18400 da41a09e17bbde1d7966a61d6c4adc35 298 Pfam PF03466 LysR substrate binding domain 91 291 1.4E-39 T 28-03-2018 IPR005119 LysR, substrate-binding CU254_RS18400 da41a09e17bbde1d7966a61d6c4adc35 298 Gene3D G3DSA:3.40.190.10 177 268 5.4E-25 T 28-03-2018 CU254_RS18400 da41a09e17bbde1d7966a61d6c4adc35 298 Gene3D G3DSA:3.40.190.10 90 176 1.4E-22 T 28-03-2018 CU254_RS18400 da41a09e17bbde1d7966a61d6c4adc35 298 SUPERFAMILY SSF53850 92 291 1.58E-35 T 28-03-2018 CU254_RS18400 da41a09e17bbde1d7966a61d6c4adc35 298 Gene3D G3DSA:1.10.10.10 2 85 8.2E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS18400 da41a09e17bbde1d7966a61d6c4adc35 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 7.2E-22 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS18400 da41a09e17bbde1d7966a61d6c4adc35 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 1.8E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS18400 da41a09e17bbde1d7966a61d6c4adc35 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 1.8E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS18400 da41a09e17bbde1d7966a61d6c4adc35 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 1.8E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS18400 da41a09e17bbde1d7966a61d6c4adc35 298 SUPERFAMILY SSF46785 4 112 4.15E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS05220 1a10645e55c784f3c63ad1c2100126f6 100 SUPERFAMILY SSF55729 8 95 5.13E-23 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS05220 1a10645e55c784f3c63ad1c2100126f6 100 Pfam PF14542 GCN5-related N-acetyl-transferase 16 92 1.1E-21 T 28-03-2018 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase CU254_RS05220 1a10645e55c784f3c63ad1c2100126f6 100 Gene3D G3DSA:3.40.630.30 1 99 1.4E-16 T 28-03-2018 CU254_RS03130 4109ab3d7fed97edcfdac8d60d929efe 722 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 591 719 4.7E-62 T 28-03-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CU254_RS03130 4109ab3d7fed97edcfdac8d60d929efe 722 Pfam PF01642 Methylmalonyl-CoA mutase 40 552 1.3E-234 T 28-03-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CU254_RS03130 4109ab3d7fed97edcfdac8d60d929efe 722 Gene3D G3DSA:3.20.20.240 39 554 3.7E-244 T 28-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CU254_RS03130 4109ab3d7fed97edcfdac8d60d929efe 722 SUPERFAMILY SSF51703 22 554 1.26E-219 T 28-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CU254_RS03130 4109ab3d7fed97edcfdac8d60d929efe 722 SUPERFAMILY SSF52242 557 718 1.96E-58 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CU254_RS03130 4109ab3d7fed97edcfdac8d60d929efe 722 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 39 559 1.6E-278 T 28-03-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CU254_RS03130 4109ab3d7fed97edcfdac8d60d929efe 722 Pfam PF02310 B12 binding domain 594 707 5.3E-15 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CU254_RS03130 4109ab3d7fed97edcfdac8d60d929efe 722 Gene3D G3DSA:3.40.50.280 575 722 4.8E-39 T 28-03-2018 CU254_RS03130 4109ab3d7fed97edcfdac8d60d929efe 722 ProSitePatterns PS00544 Methylmalonyl-CoA mutase signature. 382 407 - T 28-03-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CU254_RS23335 7d05fe6fd256c64a7b3b9488e0b2942e 302 Pfam PF01636 Phosphotransferase enzyme family 16 251 4.5E-25 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CU254_RS23335 7d05fe6fd256c64a7b3b9488e0b2942e 302 Gene3D G3DSA:3.90.1200.10 93 268 5.7E-25 T 28-03-2018 CU254_RS23335 7d05fe6fd256c64a7b3b9488e0b2942e 302 Gene3D G3DSA:3.30.200.20 10 92 4.8E-11 T 28-03-2018 CU254_RS23335 7d05fe6fd256c64a7b3b9488e0b2942e 302 PIRSF PIRSF000707 1 282 1.9E-15 T 28-03-2018 IPR016259 Hygromycin-B kinase KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 CU254_RS23335 7d05fe6fd256c64a7b3b9488e0b2942e 302 SUPERFAMILY SSF56112 14 267 4.91E-34 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS41315 78513293be2da7bb94a5a6bf230323f7 194 Pfam PF03029 Conserved hypothetical ATP binding protein 15 183 8.2E-17 T 28-03-2018 IPR004130 GPN-loop GTPase CU254_RS41315 78513293be2da7bb94a5a6bf230323f7 194 Gene3D G3DSA:3.40.50.300 2 187 8.8E-15 T 28-03-2018 CU254_RS41315 78513293be2da7bb94a5a6bf230323f7 194 SUPERFAMILY SSF52540 8 187 3.71E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS03860 48e9dcf67c38aec12960ab58defe114d 169 Pfam PF14085 Domain of unknown function (DUF4265) 35 155 4.7E-21 T 28-03-2018 IPR025361 Protein of unknown function DUF4265 CU254_RS36210 91aa8b769bdb96fe3449205aba539416 587 SUPERFAMILY SSF53067 165 345 1.3E-30 T 28-03-2018 CU254_RS36210 91aa8b769bdb96fe3449205aba539416 587 Pfam PF00012 Hsp70 protein 91 343 2.5E-26 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CU254_RS36210 91aa8b769bdb96fe3449205aba539416 587 Gene3D G3DSA:3.30.420.40 1 175 1.6E-31 T 28-03-2018 CU254_RS36210 91aa8b769bdb96fe3449205aba539416 587 SUPERFAMILY SSF53067 3 154 1.0E-22 T 28-03-2018 CU254_RS36210 91aa8b769bdb96fe3449205aba539416 587 Gene3D G3DSA:3.30.420.40 176 329 1.8E-20 T 28-03-2018 CU254_RS36210 91aa8b769bdb96fe3449205aba539416 587 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 306 320 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CU254_RS15190 88bc6cabaa354895a226247873a775bd 329 Gene3D G3DSA:1.10.10.60 213 267 3.8E-15 T 28-03-2018 CU254_RS15190 88bc6cabaa354895a226247873a775bd 329 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 269 314 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CU254_RS15190 88bc6cabaa354895a226247873a775bd 329 SUPERFAMILY SSF46689 216 266 3.96E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS15190 88bc6cabaa354895a226247873a775bd 329 SMART SM00342 232 318 1.6E-23 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS15190 88bc6cabaa354895a226247873a775bd 329 Pfam PF14525 AraC-binding-like domain 33 193 5.6E-25 T 28-03-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like CU254_RS15190 88bc6cabaa354895a226247873a775bd 329 Pfam PF12833 Helix-turn-helix domain 238 319 7.5E-23 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS15190 88bc6cabaa354895a226247873a775bd 329 Gene3D G3DSA:1.10.10.60 268 322 2.0E-9 T 28-03-2018 CU254_RS15190 88bc6cabaa354895a226247873a775bd 329 SUPERFAMILY SSF46689 269 320 1.31E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS19780 64fd167d74f5de7476032b705273884e 679 Gene3D G3DSA:1.20.1250.20 14 206 1.2E-35 T 28-03-2018 CU254_RS19780 64fd167d74f5de7476032b705273884e 679 Pfam PF07690 Major Facilitator Superfamily 29 422 1.9E-47 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS19780 64fd167d74f5de7476032b705273884e 679 Gene3D G3DSA:1.10.10.10 517 669 5.0E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS19780 64fd167d74f5de7476032b705273884e 679 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 26 440 4.5E-77 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CU254_RS19780 64fd167d74f5de7476032b705273884e 679 SUPERFAMILY SSF103473 478 509 4.45E-71 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS19780 64fd167d74f5de7476032b705273884e 679 SUPERFAMILY SSF103473 259 431 4.45E-71 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS19780 64fd167d74f5de7476032b705273884e 679 SUPERFAMILY SSF103473 11 205 4.45E-71 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS19780 64fd167d74f5de7476032b705273884e 679 Gene3D G3DSA:1.20.1250.20 263 516 2.3E-36 T 28-03-2018 CU254_RS10135 bbcf65178f15f074186dd54adadb7d13 478 SUPERFAMILY SSF48557 2 473 5.18E-116 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 CU254_RS10135 bbcf65178f15f074186dd54adadb7d13 478 Pfam PF00221 Aromatic amino acid lyase 9 434 2.1E-113 T 28-03-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 CU254_RS10135 bbcf65178f15f074186dd54adadb7d13 478 Gene3D G3DSA:1.10.275.10 1 188 2.4E-49 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal CU254_RS10135 bbcf65178f15f074186dd54adadb7d13 478 Gene3D G3DSA:1.20.200.10 189 477 8.5E-79 T 28-03-2018 CU254_RS31955 d9f1e95bad7eca97b312eb549bb5bf91 161 Gene3D G3DSA:3.10.129.10 1 154 4.5E-33 T 28-03-2018 CU254_RS31955 d9f1e95bad7eca97b312eb549bb5bf91 161 SUPERFAMILY SSF54637 10 155 1.59E-37 T 28-03-2018 IPR029069 HotDog domain CU254_RS31955 d9f1e95bad7eca97b312eb549bb5bf91 161 Pfam PF01575 MaoC like domain 20 122 9.1E-21 T 28-03-2018 IPR002539 MaoC-like domain CU254_RS15685 8cb623450a59c830e3e756b20002160f 113 Gene3D G3DSA:1.10.10.10 12 113 4.5E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS15685 8cb623450a59c830e3e756b20002160f 113 SUPERFAMILY SSF46785 3 109 2.58E-33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS15685 8cb623450a59c830e3e756b20002160f 113 Pfam PF01638 HxlR-like helix-turn-helix 14 102 3.1E-28 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type CU254_RS24330 752b111704175c500efc11f9b068fe66 327 Gene3D G3DSA:3.20.20.140 1 326 1.0E-67 T 28-03-2018 CU254_RS24330 752b111704175c500efc11f9b068fe66 327 Pfam PF00962 Adenosine/AMP deaminase 7 313 2.4E-62 T 28-03-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 CU254_RS24330 752b111704175c500efc11f9b068fe66 327 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 7 315 1.4E-79 T 28-03-2018 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 CU254_RS24330 752b111704175c500efc11f9b068fe66 327 SUPERFAMILY SSF51556 5 320 8.75E-70 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS40210 2c271af90614c3f70f54825a52aa4639 382 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 19 375 3.9E-104 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CU254_RS40210 2c271af90614c3f70f54825a52aa4639 382 SUPERFAMILY SSF53383 13 379 5.03E-101 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS40210 2c271af90614c3f70f54825a52aa4639 382 Gene3D G3DSA:3.40.640.10 11 252 6.1E-48 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS40210 2c271af90614c3f70f54825a52aa4639 382 PIRSF PIRSF000390 7 381 7.0E-103 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CU254_RS40210 2c271af90614c3f70f54825a52aa4639 382 Gene3D G3DSA:3.90.1150.10 253 382 2.4E-35 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS17130 2fce07ccca6ab564ddfcbb6435648169 93 Pfam PF09204 Bacterial self-protective colicin-like immunity 7 86 6.7E-11 T 28-03-2018 IPR015287 Colicin D immunity protein domain GO:0015643|GO:0030153 CU254_RS17130 2fce07ccca6ab564ddfcbb6435648169 93 Gene3D G3DSA:1.20.120.650 6 86 2.7E-16 T 28-03-2018 CU254_RS16610 b533991fcb45e9c2751ec63010f9b8d1 474 Gene3D G3DSA:1.20.1250.20 19 229 2.1E-24 T 28-03-2018 CU254_RS16610 b533991fcb45e9c2751ec63010f9b8d1 474 ProSitePatterns PS00217 Sugar transport proteins signature 2. 131 156 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CU254_RS16610 b533991fcb45e9c2751ec63010f9b8d1 474 Gene3D G3DSA:1.20.1250.20 247 468 3.7E-19 T 28-03-2018 CU254_RS16610 b533991fcb45e9c2751ec63010f9b8d1 474 SUPERFAMILY SSF103473 28 457 7.59E-54 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS16610 b533991fcb45e9c2751ec63010f9b8d1 474 Pfam PF00083 Sugar (and other) transporter 67 450 1.4E-31 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CU254_RS11990 c08549137f48140f66f83ba41c32531e 357 PIRSF PIRSF000355 10 357 4.7E-128 T 28-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CU254_RS11990 c08549137f48140f66f83ba41c32531e 357 SUPERFAMILY SSF47240 20 328 7.06E-95 T 28-03-2018 IPR009078 Ferritin-like superfamily CU254_RS11990 c08549137f48140f66f83ba41c32531e 357 Gene3D G3DSA:1.10.620.20 6 338 3.8E-98 T 28-03-2018 CU254_RS11990 c08549137f48140f66f83ba41c32531e 357 Pfam PF00268 Ribonucleotide reductase, small chain 37 324 3.6E-85 T 28-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CU254_RS31095 01a9d0266f2033e08c2ef2d6f3463fda 374 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 41 359 5.2E-31 T 28-03-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 CU254_RS31095 01a9d0266f2033e08c2ef2d6f3463fda 374 SUPERFAMILY SSF53649 37 372 2.24E-48 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CU254_RS31095 01a9d0266f2033e08c2ef2d6f3463fda 374 Gene3D G3DSA:3.40.720.10 32 374 2.0E-23 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CU254_RS33915 8cfe4b6dd5eefa4d204b11cd1b3aeae6 573 Pfam PF00069 Protein kinase domain 299 542 1.4E-42 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CU254_RS33915 8cfe4b6dd5eefa4d204b11cd1b3aeae6 573 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 305 328 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 CU254_RS33915 8cfe4b6dd5eefa4d204b11cd1b3aeae6 573 Gene3D G3DSA:1.10.510.10 364 559 6.0E-38 T 28-03-2018 CU254_RS33915 8cfe4b6dd5eefa4d204b11cd1b3aeae6 573 SMART SM00220 299 552 5.6E-46 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CU254_RS33915 8cfe4b6dd5eefa4d204b11cd1b3aeae6 573 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 415 427 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CU254_RS33915 8cfe4b6dd5eefa4d204b11cd1b3aeae6 573 Gene3D G3DSA:3.30.200.20 288 363 8.4E-23 T 28-03-2018 CU254_RS33915 8cfe4b6dd5eefa4d204b11cd1b3aeae6 573 SUPERFAMILY SSF56112 297 545 2.02E-60 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS03340 dadfb1219bf992a2543be3a8077c1fcb 191 Pfam PF03703 Bacterial PH domain 80 151 1.1E-18 T 28-03-2018 IPR005182 Domain of unknown function DUF304 CU254_RS23760 1248fcd2cccc2c3dc1def245add8ebd7 275 SUPERFAMILY SSF47413 29 79 5.33E-9 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS23760 1248fcd2cccc2c3dc1def245add8ebd7 275 SMART SM00530 9 81 1.4E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS23760 1248fcd2cccc2c3dc1def245add8ebd7 275 Pfam PF13560 Helix-turn-helix domain 5 84 2.6E-20 T 28-03-2018 CU254_RS23760 1248fcd2cccc2c3dc1def245add8ebd7 275 Gene3D G3DSA:1.10.260.40 1 84 1.6E-18 T 28-03-2018 CU254_RS40145 cb280e1e3cd6ecc791ec5518f5a88a81 116 Pfam PF06262 Zincin-like metallopeptidase 29 115 9.1E-33 T 28-03-2018 IPR010428 Zincin-like metallopeptidase CU254_RS40145 cb280e1e3cd6ecc791ec5518f5a88a81 116 SUPERFAMILY SSF55486 4 115 1.01E-38 T 28-03-2018 CU254_RS27280 6dd0b68f1cf71985dd0a52603be45ce5 313 SUPERFAMILY SSF63829 10 294 2.78E-15 T 28-03-2018 CU254_RS27280 6dd0b68f1cf71985dd0a52603be45ce5 313 Gene3D G3DSA:2.120.10.30 6 313 4.7E-11 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CU254_RS39360 eef6629b848db875980c0099ccf0f9a1 136 Gene3D G3DSA:3.10.180.10 4 136 1.9E-24 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS39360 eef6629b848db875980c0099ccf0f9a1 136 SUPERFAMILY SSF54593 3 134 2.69E-25 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS39360 eef6629b848db875980c0099ccf0f9a1 136 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 132 2.9E-12 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CU254_RS39300 8363280630deeb80b96e244d603a1419 212 SUPERFAMILY SSF54909 105 168 6.1E-9 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS39300 8363280630deeb80b96e244d603a1419 212 Gene3D G3DSA:3.30.70.100 9 72 0.015 T 28-03-2018 CU254_RS39300 8363280630deeb80b96e244d603a1419 212 Gene3D G3DSA:3.30.70.100 92 206 1.1E-18 T 28-03-2018 CU254_RS39300 8363280630deeb80b96e244d603a1419 212 Pfam PF03992 Antibiotic biosynthesis monooxygenase 99 183 2.4E-11 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain CU254_RS24795 0a34826892546359549e5c1a7db0ba58 544 Pfam PF00753 Metallo-beta-lactamase superfamily 10 179 2.5E-16 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS24795 0a34826892546359549e5c1a7db0ba58 544 PIRSF PIRSF004803 1 544 1.0E-196 T 28-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 CU254_RS24795 0a34826892546359549e5c1a7db0ba58 544 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 353 390 5.6E-9 T 28-03-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain CU254_RS24795 0a34826892546359549e5c1a7db0ba58 544 Gene3D G3DSA:3.60.15.10 1 440 1.7E-65 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS24795 0a34826892546359549e5c1a7db0ba58 544 Hamap MF_01491 Ribonuclease J [rnj]. 1 544 39.913 T 28-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 CU254_RS24795 0a34826892546359549e5c1a7db0ba58 544 SMART SM00849 13 207 5.0E-25 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS24795 0a34826892546359549e5c1a7db0ba58 544 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 2 541 2.4E-148 T 28-03-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 CU254_RS24795 0a34826892546359549e5c1a7db0ba58 544 ProSitePatterns PS01292 Uncharacterized protein family UPF0036 signature. 356 384 - T 28-03-2018 IPR001587 Ribonuclease J, conserved site CU254_RS24795 0a34826892546359549e5c1a7db0ba58 544 SUPERFAMILY SSF56281 1 416 4.43E-97 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS35195 6bc33b322e75334e4b9e90e3f58b5211 592 ProSitePatterns PS00080 Multicopper oxidases signature 2. 555 566 - T 28-03-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 CU254_RS35195 6bc33b322e75334e4b9e90e3f58b5211 592 ProSitePatterns PS00079 Multicopper oxidases signature 1. 550 570 - T 28-03-2018 IPR033138 Multicopper oxidases, conserved site CU254_RS35195 6bc33b322e75334e4b9e90e3f58b5211 592 SUPERFAMILY SSF49503 133 205 4.37E-21 T 28-03-2018 IPR008972 Cupredoxin CU254_RS35195 6bc33b322e75334e4b9e90e3f58b5211 592 SUPERFAMILY SSF49503 22 94 4.37E-21 T 28-03-2018 IPR008972 Cupredoxin CU254_RS35195 6bc33b322e75334e4b9e90e3f58b5211 592 Pfam PF07731 Multicopper oxidase 448 575 7.1E-22 T 28-03-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 CU254_RS35195 6bc33b322e75334e4b9e90e3f58b5211 592 Gene3D G3DSA:2.60.40.420 422 577 1.5E-26 T 28-03-2018 IPR008972 Cupredoxin CU254_RS35195 6bc33b322e75334e4b9e90e3f58b5211 592 SUPERFAMILY SSF49503 208 344 1.17E-16 T 28-03-2018 IPR008972 Cupredoxin CU254_RS35195 6bc33b322e75334e4b9e90e3f58b5211 592 Gene3D G3DSA:2.60.40.420 201 385 5.4E-27 T 28-03-2018 IPR008972 Cupredoxin CU254_RS35195 6bc33b322e75334e4b9e90e3f58b5211 592 SUPERFAMILY SSF49503 526 575 3.56E-23 T 28-03-2018 IPR008972 Cupredoxin CU254_RS35195 6bc33b322e75334e4b9e90e3f58b5211 592 SUPERFAMILY SSF49503 479 495 3.56E-23 T 28-03-2018 IPR008972 Cupredoxin CU254_RS35195 6bc33b322e75334e4b9e90e3f58b5211 592 SUPERFAMILY SSF49503 251 286 3.56E-23 T 28-03-2018 IPR008972 Cupredoxin CU254_RS35195 6bc33b322e75334e4b9e90e3f58b5211 592 Gene3D G3DSA:2.60.40.420 17 200 6.3E-26 T 28-03-2018 IPR008972 Cupredoxin CU254_RS35195 6bc33b322e75334e4b9e90e3f58b5211 592 Pfam PF07732 Multicopper oxidase 61 95 1.1E-4 T 28-03-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 CU254_RS35195 6bc33b322e75334e4b9e90e3f58b5211 592 Pfam PF07732 Multicopper oxidase 131 203 7.0E-7 T 28-03-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 CU254_RS38430 36185c7dc63b8779d12da3adb3538ce0 176 Pfam PF13302 Acetyltransferase (GNAT) domain 8 144 5.2E-23 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS38430 36185c7dc63b8779d12da3adb3538ce0 176 SUPERFAMILY SSF55729 1 170 2.8E-40 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS38430 36185c7dc63b8779d12da3adb3538ce0 176 Gene3D G3DSA:3.40.630.30 1 176 1.2E-30 T 28-03-2018 CU254_RS06680 8069875292d4651ecc476858e876a225 417 Pfam PF00534 Glycosyl transferases group 1 212 374 4.0E-39 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CU254_RS06680 8069875292d4651ecc476858e876a225 417 Pfam PF13439 Glycosyltransferase Family 4 15 195 2.2E-35 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CU254_RS06680 8069875292d4651ecc476858e876a225 417 SUPERFAMILY SSF53756 1 395 1.96E-97 T 28-03-2018 CU254_RS06680 8069875292d4651ecc476858e876a225 417 Gene3D G3DSA:3.40.50.2000 209 380 1.6E-46 T 28-03-2018 CU254_RS06680 8069875292d4651ecc476858e876a225 417 Gene3D G3DSA:3.40.50.2000 1 208 1.2E-31 T 28-03-2018 CU254_RS32450 b87ac29684022e646cf40da50fcb06d7 582 Gene3D G3DSA:2.130.10.10 335 574 2.9E-6 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CU254_RS32450 b87ac29684022e646cf40da50fcb06d7 582 SMART SM00909 212 300 1.5E-10 T 28-03-2018 IPR019606 GerMN domain CU254_RS32450 b87ac29684022e646cf40da50fcb06d7 582 Pfam PF10647 Lipoprotein LpqB beta-propeller domain 332 581 1.0E-50 T 28-03-2018 IPR018910 Lipoprotein LpqB, beta-propeller domain, C-terminal CU254_RS32450 b87ac29684022e646cf40da50fcb06d7 582 SUPERFAMILY SSF82171 328 523 3.41E-5 T 28-03-2018 CU254_RS05560 4c11e4938b06275353f84fe4815ea949 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 6.4E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS05560 4c11e4938b06275353f84fe4815ea949 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 6.4E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS05560 4c11e4938b06275353f84fe4815ea949 215 SUPERFAMILY SSF46689 16 76 2.21E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS05560 4c11e4938b06275353f84fe4815ea949 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 71 7.1E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS05560 4c11e4938b06275353f84fe4815ea949 215 Gene3D G3DSA:1.10.357.10 72 214 3.2E-7 T 28-03-2018 CU254_RS05560 4c11e4938b06275353f84fe4815ea949 215 Gene3D G3DSA:1.10.10.60 18 71 3.5E-16 T 28-03-2018 CU254_RS08430 bd62c44aebf6560d2f2af01177c2ab31 328 Pfam PF00248 Aldo/keto reductase family 18 307 1.0E-79 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS08430 bd62c44aebf6560d2f2af01177c2ab31 328 PRINTS PR00069 Aldo-keto reductase signature 139 156 1.1E-5 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CU254_RS08430 bd62c44aebf6560d2f2af01177c2ab31 328 PRINTS PR00069 Aldo-keto reductase signature 43 67 1.1E-5 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CU254_RS08430 bd62c44aebf6560d2f2af01177c2ab31 328 PRINTS PR00069 Aldo-keto reductase signature 108 126 1.1E-5 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CU254_RS08430 bd62c44aebf6560d2f2af01177c2ab31 328 Gene3D G3DSA:3.20.20.100 4 327 3.9E-110 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS08430 bd62c44aebf6560d2f2af01177c2ab31 328 SUPERFAMILY SSF51430 10 309 4.58E-102 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS29380 a3fb29d6e5c3e67e17a096c6ccd0b774 346 Gene3D G3DSA:3.90.1150.10 238 346 4.3E-21 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS29380 a3fb29d6e5c3e67e17a096c6ccd0b774 346 Pfam PF00155 Aminotransferase class I and II 31 339 2.6E-44 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CU254_RS29380 a3fb29d6e5c3e67e17a096c6ccd0b774 346 SUPERFAMILY SSF53383 5 345 2.96E-83 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS29380 a3fb29d6e5c3e67e17a096c6ccd0b774 346 Gene3D G3DSA:3.40.640.10 12 237 2.1E-48 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS22980 e06595ef0355f5004e65cb706eff173e 205 Gene3D G3DSA:3.40.50.850 1 205 5.3E-45 T 28-03-2018 CU254_RS22980 e06595ef0355f5004e65cb706eff173e 205 Pfam PF00857 Isochorismatase family 9 193 9.5E-36 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CU254_RS22980 e06595ef0355f5004e65cb706eff173e 205 SUPERFAMILY SSF52499 3 198 1.13E-43 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CU254_RS11515 2e0344f69b0f43841d1945398e90caab 401 Pfam PF02441 Flavoprotein 1 164 2.7E-37 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CU254_RS11515 2e0344f69b0f43841d1945398e90caab 401 SUPERFAMILY SSF52507 1 166 2.35E-53 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CU254_RS11515 2e0344f69b0f43841d1945398e90caab 401 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 179 368 2.1E-68 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CU254_RS11515 2e0344f69b0f43841d1945398e90caab 401 Gene3D G3DSA:3.40.50.1950 1 173 1.5E-48 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CU254_RS11515 2e0344f69b0f43841d1945398e90caab 401 Gene3D G3DSA:3.40.50.10300 174 401 1.2E-67 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CU254_RS11515 2e0344f69b0f43841d1945398e90caab 401 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 1 393 1.1E-116 T 28-03-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 CU254_RS11515 2e0344f69b0f43841d1945398e90caab 401 SUPERFAMILY SSF102645 169 397 4.45E-68 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CU254_RS18340 cf6a76ece9ea6844093318d78f2dcc27 150 Gene3D G3DSA:1.10.10.10 2 54 2.1E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS18340 cf6a76ece9ea6844093318d78f2dcc27 150 Gene3D G3DSA:3.30.70.920 55 147 9.0E-15 T 28-03-2018 CU254_RS18340 cf6a76ece9ea6844093318d78f2dcc27 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 1.4E-15 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS18340 cf6a76ece9ea6844093318d78f2dcc27 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 1.4E-15 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS18340 cf6a76ece9ea6844093318d78f2dcc27 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 1.4E-15 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS18340 cf6a76ece9ea6844093318d78f2dcc27 150 ProSitePatterns PS00519 AsnC-type HTH domain signature. 23 49 - T 28-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site CU254_RS18340 cf6a76ece9ea6844093318d78f2dcc27 150 Pfam PF01037 Lrp/AsnC ligand binding domain 70 141 2.3E-12 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CU254_RS18340 cf6a76ece9ea6844093318d78f2dcc27 150 SMART SM00344 5 112 3.9E-36 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CU254_RS18340 cf6a76ece9ea6844093318d78f2dcc27 150 SUPERFAMILY SSF46785 5 64 7.49E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS18340 cf6a76ece9ea6844093318d78f2dcc27 150 Pfam PF13404 AsnC-type helix-turn-helix domain 7 46 1.0E-15 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS18340 cf6a76ece9ea6844093318d78f2dcc27 150 SUPERFAMILY SSF54909 66 144 2.15E-12 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS32155 565c6206cc9c7614a1e644b02a16a130 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 1.1E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS32155 565c6206cc9c7614a1e644b02a16a130 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 1.1E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS32155 565c6206cc9c7614a1e644b02a16a130 188 Gene3D G3DSA:1.10.10.60 2 56 5.9E-20 T 28-03-2018 CU254_RS32155 565c6206cc9c7614a1e644b02a16a130 188 SUPERFAMILY SSF46689 5 82 1.59E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS32155 565c6206cc9c7614a1e644b02a16a130 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 58 5.8E-18 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS32155 565c6206cc9c7614a1e644b02a16a130 188 Gene3D G3DSA:1.10.357.10 57 188 1.0E-19 T 28-03-2018 CU254_RS32155 565c6206cc9c7614a1e644b02a16a130 188 SUPERFAMILY SSF48498 79 184 1.09E-9 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS21570 3b1bd28a498d51c2a5cc7874b05d4360 143 Pfam PF00011 Hsp20/alpha crystallin family 37 132 7.2E-21 T 28-03-2018 IPR002068 Alpha crystallin/Hsp20 domain CU254_RS21570 3b1bd28a498d51c2a5cc7874b05d4360 143 SUPERFAMILY SSF49764 6 132 1.92E-31 T 28-03-2018 IPR008978 HSP20-like chaperone CU254_RS21570 3b1bd28a498d51c2a5cc7874b05d4360 143 Gene3D G3DSA:2.60.40.790 2 134 2.3E-29 T 28-03-2018 IPR008978 HSP20-like chaperone CU254_RS07870 1063ee300d1ad8a538e6cc50cb5a9170 54 Pfam PF01402 Ribbon-helix-helix protein, copG family 9 44 4.2E-5 T 28-03-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 CU254_RS07870 1063ee300d1ad8a538e6cc50cb5a9170 54 Gene3D G3DSA:1.10.1220.10 3 44 8.3E-13 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CU254_RS07870 1063ee300d1ad8a538e6cc50cb5a9170 54 SUPERFAMILY SSF47598 4 48 1.02E-7 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 CU254_RS11630 b42eb638203a50dde816fe68df08bb39 320 SUPERFAMILY SSF142338 2 308 2.35E-79 T 28-03-2018 CU254_RS11630 b42eb638203a50dde816fe68df08bb39 320 Pfam PF01933 Uncharacterised protein family UPF0052 4 278 4.8E-71 T 28-03-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 CU254_RS11630 b42eb638203a50dde816fe68df08bb39 320 Hamap MF_00973 Gluconeogenesis factor. 1 314 30.898 T 28-03-2018 IPR010119 Gluconeogenesis factor CU254_RS11630 b42eb638203a50dde816fe68df08bb39 320 Gene3D G3DSA:3.40.50.10680 81 314 2.1E-51 T 28-03-2018 CU254_RS11630 b42eb638203a50dde816fe68df08bb39 320 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 4 277 3.8E-85 T 28-03-2018 IPR010119 Gluconeogenesis factor CU254_RS08825 59e59af5e6d0dc2675e26b435401fe74 329 Pfam PF00248 Aldo/keto reductase family 15 314 7.5E-77 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS08825 59e59af5e6d0dc2675e26b435401fe74 329 SUPERFAMILY SSF51430 1 315 3.54E-97 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS08825 59e59af5e6d0dc2675e26b435401fe74 329 PRINTS PR00069 Aldo-keto reductase signature 106 124 2.3E-5 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CU254_RS08825 59e59af5e6d0dc2675e26b435401fe74 329 PRINTS PR00069 Aldo-keto reductase signature 137 154 2.3E-5 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CU254_RS08825 59e59af5e6d0dc2675e26b435401fe74 329 PRINTS PR00069 Aldo-keto reductase signature 40 64 2.3E-5 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CU254_RS08825 59e59af5e6d0dc2675e26b435401fe74 329 Gene3D G3DSA:3.20.20.100 3 318 3.7E-95 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS02360 60a87c9664c3ad039e64ad394c3ac166 442 Pfam PF13641 Glycosyltransferase like family 2 34 286 5.0E-23 T 28-03-2018 CU254_RS02360 60a87c9664c3ad039e64ad394c3ac166 442 Gene3D G3DSA:3.90.550.10 16 319 3.7E-31 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS02360 60a87c9664c3ad039e64ad394c3ac166 442 SUPERFAMILY SSF53448 35 333 3.84E-28 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS40490 dcc23400b7112a0831608644d0d2b622 313 Pfam PF02615 Malate/L-lactate dehydrogenase 32 194 6.8E-27 T 28-03-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0008152|GO:0016491|GO:0055114 CU254_RS40490 dcc23400b7112a0831608644d0d2b622 313 Pfam PF02615 Malate/L-lactate dehydrogenase 208 297 1.7E-10 T 28-03-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0008152|GO:0016491|GO:0055114 CU254_RS40490 dcc23400b7112a0831608644d0d2b622 313 Gene3D G3DSA:3.30.1370.60 103 216 1.0E-17 T 28-03-2018 CU254_RS40490 dcc23400b7112a0831608644d0d2b622 313 Gene3D G3DSA:1.10.1530.10 30 102 1.4E-13 T 28-03-2018 CU254_RS40490 dcc23400b7112a0831608644d0d2b622 313 Gene3D G3DSA:3.30.1370.60 217 269 0.0017 T 28-03-2018 CU254_RS40490 dcc23400b7112a0831608644d0d2b622 313 SUPERFAMILY SSF89733 29 306 3.4E-42 T 28-03-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0008152|GO:0016491|GO:0055114 CU254_RS28825 bf1faaec81fbf2130f013ddf7f7c8621 310 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 124 303 3.1E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS28825 bf1faaec81fbf2130f013ddf7f7c8621 310 SUPERFAMILY SSF161098 102 286 5.23E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS28825 bf1faaec81fbf2130f013ddf7f7c8621 310 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 31 75 1.4E-9 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CU254_RS28825 bf1faaec81fbf2130f013ddf7f7c8621 310 Gene3D G3DSA:1.10.3720.10 30 294 8.4E-31 T 28-03-2018 CU254_RS33645 70f17d6335b8c61f2e976ab39fdff4e4 267 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS33645 70f17d6335b8c61f2e976ab39fdff4e4 267 SMART SM00382 42 227 1.2E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS33645 70f17d6335b8c61f2e976ab39fdff4e4 267 Gene3D G3DSA:3.40.50.300 17 247 1.3E-58 T 28-03-2018 CU254_RS33645 70f17d6335b8c61f2e976ab39fdff4e4 267 Pfam PF00005 ABC transporter 45 179 1.4E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS33645 70f17d6335b8c61f2e976ab39fdff4e4 267 SUPERFAMILY SSF52540 28 231 2.61E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS06615 f265ce1829c7b5ea476fd24db54d0cb7 244 Gene3D G3DSA:1.25.40.10 6 131 0.086 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS06615 f265ce1829c7b5ea476fd24db54d0cb7 244 SUPERFAMILY SSF48452 9 34 4.74E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS06615 f265ce1829c7b5ea476fd24db54d0cb7 244 SUPERFAMILY SSF48452 131 213 4.74E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS06615 f265ce1829c7b5ea476fd24db54d0cb7 244 Gene3D G3DSA:1.25.40.10 198 224 0.074 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS06615 f265ce1829c7b5ea476fd24db54d0cb7 244 Gene3D G3DSA:1.10.150.200 132 197 1.6E-5 T 28-03-2018 CU254_RS31180 d2c97403ac17c5e3bc5b73e243eae18c 332 Gene3D G3DSA:3.40.50.880 1 188 3.5E-44 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS31180 d2c97403ac17c5e3bc5b73e243eae18c 332 Gene3D G3DSA:1.10.10.60 268 320 7.4E-12 T 28-03-2018 CU254_RS31180 d2c97403ac17c5e3bc5b73e243eae18c 332 SMART SM00342 227 310 2.9E-22 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS31180 d2c97403ac17c5e3bc5b73e243eae18c 332 SUPERFAMILY SSF46689 264 314 2.94E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS31180 d2c97403ac17c5e3bc5b73e243eae18c 332 SUPERFAMILY SSF52317 1 192 1.72E-40 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS31180 d2c97403ac17c5e3bc5b73e243eae18c 332 Gene3D G3DSA:1.10.10.60 189 267 5.3E-11 T 28-03-2018 CU254_RS31180 d2c97403ac17c5e3bc5b73e243eae18c 332 SUPERFAMILY SSF46689 213 260 2.09E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS31180 d2c97403ac17c5e3bc5b73e243eae18c 332 Pfam PF01965 DJ-1/PfpI family 84 171 5.4E-9 T 28-03-2018 IPR002818 DJ-1/PfpI CU254_RS31180 d2c97403ac17c5e3bc5b73e243eae18c 332 Pfam PF12833 Helix-turn-helix domain 233 311 6.6E-19 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS04420 afeddbd3dd5090635e9e78d3d4567e2a 295 PIRSF PIRSF000388 26 295 1.4E-109 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CU254_RS04420 afeddbd3dd5090635e9e78d3d4567e2a 295 Pfam PF02548 Ketopantoate hydroxymethyltransferase 33 289 3.1E-108 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CU254_RS04420 afeddbd3dd5090635e9e78d3d4567e2a 295 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 34 294 42.447 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CU254_RS04420 afeddbd3dd5090635e9e78d3d4567e2a 295 SUPERFAMILY SSF51621 33 292 7.07E-103 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CU254_RS04420 afeddbd3dd5090635e9e78d3d4567e2a 295 Gene3D G3DSA:3.20.20.60 22 294 2.4E-85 T 28-03-2018 CU254_RS04420 afeddbd3dd5090635e9e78d3d4567e2a 295 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 33 295 1.6E-91 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CU254_RS03820 67e096ddb80077048942e94a53477a7a 114 Pfam PF13828 Domain of unknown function (DUF4190) 38 98 1.2E-12 T 28-03-2018 IPR025241 Domain of unknown function DUF4190 CU254_RS23360 7933f315c9f1f3118cb1d69c81627a4c 364 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 11 262 1.5E-46 T 28-03-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CU254_RS23360 7933f315c9f1f3118cb1d69c81627a4c 364 Hamap MF_01609 Glutamate--cysteine ligase [gshA]. 1 364 69.59 T 28-03-2018 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CU254_RS23360 7933f315c9f1f3118cb1d69c81627a4c 364 SUPERFAMILY SSF55931 4 361 1.88E-85 T 28-03-2018 CU254_RS23360 7933f315c9f1f3118cb1d69c81627a4c 364 TIGRFAM TIGR02050 gshA_cyan_rel: carboxylate-amine ligase, YbdK family 10 289 1.4E-79 T 28-03-2018 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CU254_RS22115 0efc7949c7cf58be7fc6a82743de9139 385 Gene3D G3DSA:3.90.25.10 210 374 5.5E-18 T 28-03-2018 CU254_RS22115 0efc7949c7cf58be7fc6a82743de9139 385 Gene3D G3DSA:3.40.50.720 2 209 3.5E-15 T 28-03-2018 CU254_RS22115 0efc7949c7cf58be7fc6a82743de9139 385 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 291 3.1E-22 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CU254_RS22115 0efc7949c7cf58be7fc6a82743de9139 385 SUPERFAMILY SSF51735 1 364 3.78E-56 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS34160 bac69a2843474b398f8cdb2940d0b061 219 Gene3D G3DSA:3.90.1210.10 52 116 1.8E-15 T 28-03-2018 CU254_RS34160 bac69a2843474b398f8cdb2940d0b061 219 SMART SM00858 53 115 3.5E-8 T 28-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 CU254_RS34160 bac69a2843474b398f8cdb2940d0b061 219 Pfam PF08666 SAF domain 56 110 2.3E-6 T 28-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 CU254_RS30125 0ad80ad72efc1fd1603fedac682fc9fa 260 Gene3D G3DSA:3.40.50.1820 6 252 5.4E-41 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS30125 0ad80ad72efc1fd1603fedac682fc9fa 260 SUPERFAMILY SSF53474 6 250 2.03E-54 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS30125 0ad80ad72efc1fd1603fedac682fc9fa 260 Pfam PF00975 Thioesterase domain 26 248 5.1E-54 T 28-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CU254_RS30125 0ad80ad72efc1fd1603fedac682fc9fa 260 SMART SM00824 Thioesterase 28 250 1.0E-5 T 28-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 CU254_RS35305 be33c8b43e7db740e7c1f7c116173197 261 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 244 3.5E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS35305 be33c8b43e7db740e7c1f7c116173197 261 Gene3D G3DSA:1.10.3720.10 8 257 3.5E-22 T 28-03-2018 CU254_RS35305 be33c8b43e7db740e7c1f7c116173197 261 SUPERFAMILY SSF161098 62 241 1.44E-27 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS10035 24ba1b33348e84ae21c3a695fb63f08c 385 Gene3D G3DSA:3.40.50.300 2 255 1.3E-55 T 28-03-2018 CU254_RS10035 24ba1b33348e84ae21c3a695fb63f08c 385 TIGRFAM TIGR00345 GET3_arsA_TRC40: transport-energizing ATPase, TRC40/GET3/ArsA family 5 292 3.4E-54 T 28-03-2018 IPR016300 Arsenical pump ATPase, ArsA/GET3 GO:0005524|GO:0016887 Reactome: R-HSA-381038 CU254_RS10035 24ba1b33348e84ae21c3a695fb63f08c 385 Pfam PF02374 Anion-transporting ATPase 1 293 1.5E-59 T 28-03-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 CU254_RS10035 24ba1b33348e84ae21c3a695fb63f08c 385 SUPERFAMILY SSF52540 1 260 2.0E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS35560 3fdb3e3269b80d14306353975adb96f0 348 Gene3D G3DSA:3.40.50.10490 8 187 3.0E-34 T 28-03-2018 CU254_RS35560 3fdb3e3269b80d14306353975adb96f0 348 Gene3D G3DSA:3.40.50.10490 195 348 4.7E-27 T 28-03-2018 CU254_RS35560 3fdb3e3269b80d14306353975adb96f0 348 SUPERFAMILY SSF53697 10 346 1.05E-63 T 28-03-2018 CU254_RS35560 3fdb3e3269b80d14306353975adb96f0 348 Pfam PF01380 SIS domain 48 168 1.1E-13 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CU254_RS35560 3fdb3e3269b80d14306353975adb96f0 348 Pfam PF01380 SIS domain 208 295 2.4E-10 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CU254_RS38970 9687994116bd9d389e50d0a4e4287b09 454 Gene3D G3DSA:1.10.287.850 79 168 1.8E-4 T 28-03-2018 CU254_RS11840 2fd99c387a93ca2adf3430f02b50683b 291 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 71 214 5.8E-16 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CU254_RS11840 2fd99c387a93ca2adf3430f02b50683b 291 Gene3D G3DSA:2.10.109.10 72 232 1.1E-11 T 28-03-2018 CU254_RS11840 2fd99c387a93ca2adf3430f02b50683b 291 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 173 192 1.4E-5 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CU254_RS11840 2fd99c387a93ca2adf3430f02b50683b 291 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 129 141 1.4E-5 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CU254_RS11840 2fd99c387a93ca2adf3430f02b50683b 291 SUPERFAMILY SSF51306 78 215 9.94E-19 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CU254_RS03690 b5717d423fb5adc9517719b4e54459d1 329 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 3 316 2.1E-63 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CU254_RS17385 b2b446d586a1ca17c0512185c975cd03 375 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 4 372 4.7E-118 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CU254_RS17385 b2b446d586a1ca17c0512185c975cd03 375 Gene3D G3DSA:3.40.640.10 1 242 3.3E-50 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS17385 b2b446d586a1ca17c0512185c975cd03 375 Gene3D G3DSA:3.90.1150.10 243 374 2.4E-42 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS17385 b2b446d586a1ca17c0512185c975cd03 375 PIRSF PIRSF001434 1 374 1.3E-126 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CU254_RS17385 b2b446d586a1ca17c0512185c975cd03 375 SUPERFAMILY SSF53383 27 372 4.32E-95 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS02450 b0c184ce3c7beb91a40d6718851c62f3 207 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 4 190 1.6E-26 T 28-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CU254_RS02450 b0c184ce3c7beb91a40d6718851c62f3 207 SUPERFAMILY SSF55718 158 203 4.71E-5 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CU254_RS02450 b0c184ce3c7beb91a40d6718851c62f3 207 SUPERFAMILY SSF109854 3 130 3.3E-34 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CU254_RS02450 b0c184ce3c7beb91a40d6718851c62f3 207 Gene3D G3DSA:1.20.120.450 1 130 1.4E-23 T 28-03-2018 CU254_RS02450 b0c184ce3c7beb91a40d6718851c62f3 207 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 3 123 1.1E-22 T 28-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CU254_RS24175 0039af7893260bad7e37e456c71e21f5 394 Gene3D G3DSA:3.40.47.10 3 156 1.1E-5 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS24175 0039af7893260bad7e37e456c71e21f5 394 PIRSF PIRSF000429 7 342 6.2E-24 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CU254_RS24175 0039af7893260bad7e37e456c71e21f5 394 Gene3D G3DSA:3.40.47.10 157 385 4.7E-23 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS24175 0039af7893260bad7e37e456c71e21f5 394 SUPERFAMILY SSF53901 241 382 1.62E-18 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS24175 0039af7893260bad7e37e456c71e21f5 394 SUPERFAMILY SSF53901 1 123 3.27E-21 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS24175 0039af7893260bad7e37e456c71e21f5 394 SUPERFAMILY SSF53901 210 235 3.27E-21 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS19690 5dda745ae44855d5336932e347966721 440 SUPERFAMILY SSF53187 5 204 1.77E-53 T 28-03-2018 CU254_RS19690 5dda745ae44855d5336932e347966721 440 SUPERFAMILY SSF53187 350 438 1.77E-53 T 28-03-2018 CU254_RS19690 5dda745ae44855d5336932e347966721 440 Gene3D G3DSA:3.40.630.10 4 207 9.8E-43 T 28-03-2018 CU254_RS19690 5dda745ae44855d5336932e347966721 440 Gene3D G3DSA:3.30.70.360 208 344 5.6E-22 T 28-03-2018 CU254_RS19690 5dda745ae44855d5336932e347966721 440 Pfam PF07687 Peptidase dimerisation domain 201 323 4.5E-14 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CU254_RS19690 5dda745ae44855d5336932e347966721 440 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 83 92 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CU254_RS19690 5dda745ae44855d5336932e347966721 440 Pfam PF01546 Peptidase family M20/M25/M40 84 438 1.8E-37 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CU254_RS19690 5dda745ae44855d5336932e347966721 440 SUPERFAMILY SSF55031 290 325 3.72E-10 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CU254_RS19690 5dda745ae44855d5336932e347966721 440 SUPERFAMILY SSF55031 204 246 3.72E-10 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CU254_RS38980 13ec443dc13771a9bbffe4f7bcad9e19 467 Gene3D G3DSA:1.10.860.10 25 175 2.3E-52 T 28-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal CU254_RS38980 13ec443dc13771a9bbffe4f7bcad9e19 467 SMART SM00382 226 423 3.9E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS38980 13ec443dc13771a9bbffe4f7bcad9e19 467 Pfam PF03796 DnaB-like helicase C terminal domain 209 463 1.1E-99 T 28-03-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 CU254_RS38980 13ec443dc13771a9bbffe4f7bcad9e19 467 Gene3D G3DSA:3.40.50.300 191 467 1.2E-66 T 28-03-2018 CU254_RS38980 13ec443dc13771a9bbffe4f7bcad9e19 467 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 30 465 1.1E-157 T 28-03-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 CU254_RS38980 13ec443dc13771a9bbffe4f7bcad9e19 467 Pfam PF00772 DnaB-like helicase N terminal domain 29 131 2.9E-33 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CU254_RS38980 13ec443dc13771a9bbffe4f7bcad9e19 467 SUPERFAMILY SSF52540 208 452 2.63E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS38980 13ec443dc13771a9bbffe4f7bcad9e19 467 SUPERFAMILY SSF48024 28 139 1.29E-37 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CU254_RS09730 435db9255050a59970a9292791fdc5fb 417 SUPERFAMILY SSF103473 12 402 3.66E-42 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS09730 435db9255050a59970a9292791fdc5fb 417 Gene3D G3DSA:1.20.1250.20 213 407 9.7E-16 T 28-03-2018 CU254_RS09730 435db9255050a59970a9292791fdc5fb 417 Gene3D G3DSA:1.20.1250.20 4 204 2.5E-17 T 28-03-2018 CU254_RS09730 435db9255050a59970a9292791fdc5fb 417 Pfam PF05977 Transmembrane secretion effector 9 405 2.1E-29 T 28-03-2018 IPR010290 Transmembrane secretion effector CU254_RS33935 79d3035818f9e1f0fe6cce0426f6245e 228 Gene3D G3DSA:2.40.33.20 2 224 1.5E-38 T 28-03-2018 CU254_RS33935 79d3035818f9e1f0fe6cce0426f6245e 228 SUPERFAMILY SSF50800 6 218 1.26E-49 T 28-03-2018 IPR011037 Pyruvate kinase-like, insert domain CU254_RS33935 79d3035818f9e1f0fe6cce0426f6245e 228 Pfam PF03473 MOSC domain 51 154 2.9E-17 T 28-03-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 CU254_RS08905 aea4fbf65de43fa34ae6252643793aa8 553 Pfam PF13631 Cytochrome b(N-terminal)/b6/petB 124 298 4.8E-63 T 28-03-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 CU254_RS08905 aea4fbf65de43fa34ae6252643793aa8 553 SUPERFAMILY SSF81342 25 304 2.04E-61 T 28-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 CU254_RS08905 aea4fbf65de43fa34ae6252643793aa8 553 Gene3D G3DSA:1.20.810.10 24 446 6.2E-102 T 28-03-2018 IPR027387 Cytochrome b/b6-like domain Reactome: R-HSA-611105 CU254_RS34950 68e4d706e61d0d97328f1b14c231832e 233 PIRSF PIRSF005624 17 232 5.4E-42 T 28-03-2018 IPR012202 [NiFe]-hydrogenase/urease maturation factor, Ni2-binding GTPase GO:0003924|GO:0016151 CU254_RS34950 68e4d706e61d0d97328f1b14c231832e 233 Gene3D G3DSA:3.40.50.300 34 230 3.6E-18 T 28-03-2018 CU254_RS34950 68e4d706e61d0d97328f1b14c231832e 233 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 37 207 3.8E-32 T 28-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CU254_RS34950 68e4d706e61d0d97328f1b14c231832e 233 SUPERFAMILY SSF52540 20 231 1.09E-36 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS34950 68e4d706e61d0d97328f1b14c231832e 233 TIGRFAM TIGR00101 ureG: urease accessory protein UreG 36 230 2.5E-78 T 28-03-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 CU254_RS34950 68e4d706e61d0d97328f1b14c231832e 233 Hamap MF_01389 Urease accessory protein UreG [ureG]. 33 231 42.083 T 28-03-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 CU254_RS26580 318117623d99c1df625c3148b9f47af3 306 SMART SM00829 11 304 5.1E-18 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CU254_RS26580 318117623d99c1df625c3148b9f47af3 306 Pfam PF13602 Zinc-binding dehydrogenase 200 304 1.7E-13 T 28-03-2018 CU254_RS26580 318117623d99c1df625c3148b9f47af3 306 SUPERFAMILY SSF50129 3 150 2.59E-33 T 28-03-2018 IPR011032 GroES-like CU254_RS26580 318117623d99c1df625c3148b9f47af3 306 SUPERFAMILY SSF51735 116 236 4.04E-25 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS26580 318117623d99c1df625c3148b9f47af3 306 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 124 3.4E-10 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CU254_RS26580 318117623d99c1df625c3148b9f47af3 306 Gene3D G3DSA:3.90.180.10 150 306 4.3E-16 T 28-03-2018 CU254_RS26580 318117623d99c1df625c3148b9f47af3 306 Gene3D G3DSA:3.90.180.10 2 149 1.3E-47 T 28-03-2018 CU254_RS22005 9533a1d585d3cf962a426d5ea9f8f076 708 SMART SM00642 158 568 3.4E-9 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CU254_RS22005 9533a1d585d3cf962a426d5ea9f8f076 708 SUPERFAMILY SSF51011 591 701 1.29E-24 T 28-03-2018 CU254_RS22005 9533a1d585d3cf962a426d5ea9f8f076 708 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 10 96 5.3E-16 T 28-03-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077 CU254_RS22005 9533a1d585d3cf962a426d5ea9f8f076 708 SUPERFAMILY SSF81296 5 147 2.44E-42 T 28-03-2018 IPR014756 Immunoglobulin E-set CU254_RS22005 9533a1d585d3cf962a426d5ea9f8f076 708 Gene3D G3DSA:2.60.40.10 6 136 9.8E-49 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS22005 9533a1d585d3cf962a426d5ea9f8f076 708 Gene3D G3DSA:3.20.20.80 138 580 3.7E-112 T 28-03-2018 CU254_RS22005 9533a1d585d3cf962a426d5ea9f8f076 708 SUPERFAMILY SSF51445 500 576 1.21E-134 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS22005 9533a1d585d3cf962a426d5ea9f8f076 708 SUPERFAMILY SSF51445 135 471 1.21E-134 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS22005 9533a1d585d3cf962a426d5ea9f8f076 708 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 6 701 0.0 T 28-03-2018 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 CU254_RS22005 9533a1d585d3cf962a426d5ea9f8f076 708 Gene3D G3DSA:2.60.40.1180 581 705 3.7E-32 T 28-03-2018 CU254_RS22005 9533a1d585d3cf962a426d5ea9f8f076 708 Pfam PF00128 Alpha amylase, catalytic domain 301 530 4.8E-7 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CU254_RS22005 9533a1d585d3cf962a426d5ea9f8f076 708 Pfam PF00128 Alpha amylase, catalytic domain 189 277 3.1E-8 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CU254_RS37110 421c59577f88105fea01fec47b5ed97a 269 SUPERFAMILY SSF53335 16 224 6.91E-30 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS37110 421c59577f88105fea01fec47b5ed97a 269 Gene3D G3DSA:3.40.50.150 1 257 2.4E-38 T 28-03-2018 CU254_RS31680 cf185db52b43554bcbc9ec55b4569088 237 Gene3D G3DSA:3.20.20.70 1 237 5.3E-59 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS31680 cf185db52b43554bcbc9ec55b4569088 237 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 5 218 2.4E-56 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CU254_RS31680 cf185db52b43554bcbc9ec55b4569088 237 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 2 235 28.228 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CU254_RS31680 cf185db52b43554bcbc9ec55b4569088 237 Pfam PF00290 Tryptophan synthase alpha chain 3 217 1.3E-63 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CU254_RS31680 cf185db52b43554bcbc9ec55b4569088 237 SUPERFAMILY SSF51366 3 219 3.77E-62 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CU254_RS37135 513132666b6616d6c00dc9469fe02772 301 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 18 293 4.7E-61 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CU254_RS37135 513132666b6616d6c00dc9469fe02772 301 Gene3D G3DSA:3.40.50.1100 27 132 5.1E-28 T 28-03-2018 CU254_RS37135 513132666b6616d6c00dc9469fe02772 301 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 41 54 - T 28-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 CU254_RS37135 513132666b6616d6c00dc9469fe02772 301 SUPERFAMILY SSF53686 8 282 3.93E-69 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CU254_RS37135 513132666b6616d6c00dc9469fe02772 301 Gene3D G3DSA:3.40.50.1100 133 298 7.5E-30 T 28-03-2018 CU254_RS09080 f3a019c390ba38f40d283eddcdbcdba9 1314 Gene3D G3DSA:3.40.50.300 1040 1261 2.2E-4 T 28-03-2018 CU254_RS09080 f3a019c390ba38f40d283eddcdbcdba9 1314 Gene3D G3DSA:3.40.50.300 788 1016 3.0E-11 T 28-03-2018 CU254_RS09080 f3a019c390ba38f40d283eddcdbcdba9 1314 Gene3D G3DSA:3.40.50.300 439 664 7.3E-20 T 28-03-2018 CU254_RS09080 f3a019c390ba38f40d283eddcdbcdba9 1314 SUPERFAMILY SSF52540 434 685 6.07E-31 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS09080 f3a019c390ba38f40d283eddcdbcdba9 1314 SUPERFAMILY SSF52540 756 1022 3.52E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS09080 f3a019c390ba38f40d283eddcdbcdba9 1314 Pfam PF01580 FtsK/SpoIIIE family 800 1033 4.1E-49 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CU254_RS09080 f3a019c390ba38f40d283eddcdbcdba9 1314 Pfam PF01580 FtsK/SpoIIIE family 440 562 9.8E-25 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CU254_RS09080 f3a019c390ba38f40d283eddcdbcdba9 1314 Pfam PF01580 FtsK/SpoIIIE family 1093 1181 3.9E-7 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CU254_RS09080 f3a019c390ba38f40d283eddcdbcdba9 1314 TIGRFAM TIGR03925 T7SS_EccC_b: type VII secretion protein EccCb 737 1307 3.6E-223 T 28-03-2018 IPR023837 EccCb-like, Actinobacteria CU254_RS09080 f3a019c390ba38f40d283eddcdbcdba9 1314 TIGRFAM TIGR03924 T7SS_EccC_a: type VII secretion protein EccCa 20 692 1.1E-248 T 28-03-2018 IPR023836 EccCa-like, Actinobacteria CU254_RS09080 f3a019c390ba38f40d283eddcdbcdba9 1314 SUPERFAMILY SSF52540 1061 1241 4.51E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS09080 f3a019c390ba38f40d283eddcdbcdba9 1314 SMART SM00382 818 996 1.9E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS09080 f3a019c390ba38f40d283eddcdbcdba9 1314 SMART SM00382 1103 1266 21.0 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS09080 f3a019c390ba38f40d283eddcdbcdba9 1314 SMART SM00382 469 649 0.16 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS26190 5a5c39a2a50dc1bcc8afba097f0e5e84 108 Gene3D G3DSA:3.30.1310.10 1 102 4.9E-14 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CU254_RS26190 5a5c39a2a50dc1bcc8afba097f0e5e84 108 Pfam PF02575 YbaB/EbfC DNA-binding family 35 97 1.2E-6 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CU254_RS26190 5a5c39a2a50dc1bcc8afba097f0e5e84 108 SUPERFAMILY SSF82607 29 95 2.62E-5 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CU254_RS34165 6a8a73fb0e86a0e113901fecadc7e543 139 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 4 18 8.9E-7 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CU254_RS34165 6a8a73fb0e86a0e113901fecadc7e543 139 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 79 87 8.9E-7 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CU254_RS34165 6a8a73fb0e86a0e113901fecadc7e543 139 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 89 98 8.9E-7 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CU254_RS34165 6a8a73fb0e86a0e113901fecadc7e543 139 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 11 24 - T 28-03-2018 IPR019823 Large-conductance mechanosensitive channel, conserved site CU254_RS34165 6a8a73fb0e86a0e113901fecadc7e543 139 Gene3D G3DSA:1.20.5.220 110 129 8.2E-5 T 28-03-2018 CU254_RS34165 6a8a73fb0e86a0e113901fecadc7e543 139 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 2 129 2.5E-30 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CU254_RS34165 6a8a73fb0e86a0e113901fecadc7e543 139 SUPERFAMILY SSF81330 10 123 4.71E-29 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CU254_RS34165 6a8a73fb0e86a0e113901fecadc7e543 139 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 2 126 3.6E-38 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CU254_RS37990 4530366e23324b1cfe770f8ca502a2fb 389 Gene3D G3DSA:1.20.1050.50 30 169 6.2E-25 T 28-03-2018 CU254_RS33910 3f2d1584ba493b6948bc9311dd455690 189 Gene3D G3DSA:3.40.50.150 9 189 3.2E-28 T 28-03-2018 CU254_RS33910 3f2d1584ba493b6948bc9311dd455690 189 Pfam PF08241 Methyltransferase domain 38 130 2.4E-17 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CU254_RS33910 3f2d1584ba493b6948bc9311dd455690 189 SUPERFAMILY SSF53335 28 178 2.28E-28 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS25045 c0aeefeba8734915279388b214ed8ac6 179 SUPERFAMILY SSF46785 36 171 6.82E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS25045 c0aeefeba8734915279388b214ed8ac6 179 SMART SM00347 58 158 3.6E-16 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS25045 c0aeefeba8734915279388b214ed8ac6 179 PRINTS PR00598 Bacterial regulatory protein MarR family signature 99 114 6.4E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS25045 c0aeefeba8734915279388b214ed8ac6 179 PRINTS PR00598 Bacterial regulatory protein MarR family signature 118 134 6.4E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS25045 c0aeefeba8734915279388b214ed8ac6 179 PRINTS PR00598 Bacterial regulatory protein MarR family signature 82 98 6.4E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS25045 c0aeefeba8734915279388b214ed8ac6 179 PRINTS PR00598 Bacterial regulatory protein MarR family signature 148 168 6.4E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS25045 c0aeefeba8734915279388b214ed8ac6 179 Pfam PF12802 MarR family 69 122 1.1E-9 T 28-03-2018 CU254_RS25045 c0aeefeba8734915279388b214ed8ac6 179 ProSitePatterns PS01117 MarR-type HTH domain signature. 96 131 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CU254_RS25045 c0aeefeba8734915279388b214ed8ac6 179 Gene3D G3DSA:1.10.10.10 2 171 1.7E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS14135 4fa0bfb2f8fd2f3f6afcf934ca88045e 275 SUPERFAMILY SSF47090 55 116 2.88E-6 T 28-03-2018 IPR002477 Peptidoglycan binding-like CU254_RS14135 4fa0bfb2f8fd2f3f6afcf934ca88045e 275 Gene3D G3DSA:1.10.101.10 45 120 3.3E-7 T 28-03-2018 IPR002477 Peptidoglycan binding-like CU254_RS21595 366e5c96ecde54cd49c1708aca61ca2f 106 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 7 101 3.8E-14 T 28-03-2018 IPR008407 Branched-chain amino acid transport, AzlD CU254_RS10380 2f74c7e78d37191e735337debb8bb96e 313 SUPERFAMILY SSF53474 43 290 4.43E-48 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS10380 2f74c7e78d37191e735337debb8bb96e 313 Pfam PF00561 alpha/beta hydrolase fold 56 278 3.0E-18 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS10380 2f74c7e78d37191e735337debb8bb96e 313 Gene3D G3DSA:3.40.50.1820 41 294 1.4E-36 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS09810 bb222b2d96f5d18a9cfaa9eaf4f5e9da 669 Pfam PF00326 Prolyl oligopeptidase family 466 668 7.0E-54 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CU254_RS09810 bb222b2d96f5d18a9cfaa9eaf4f5e9da 669 SUPERFAMILY SSF53474 414 666 1.53E-53 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS09810 bb222b2d96f5d18a9cfaa9eaf4f5e9da 669 SUPERFAMILY SSF50993 2 409 1.15E-53 T 28-03-2018 CU254_RS09810 bb222b2d96f5d18a9cfaa9eaf4f5e9da 669 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 2 220 1.3E-21 T 28-03-2018 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 CU254_RS09810 bb222b2d96f5d18a9cfaa9eaf4f5e9da 669 Gene3D G3DSA:3.40.50.1820 1 669 8.2E-74 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS09810 bb222b2d96f5d18a9cfaa9eaf4f5e9da 669 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 601 623 9.5E-48 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CU254_RS09810 bb222b2d96f5d18a9cfaa9eaf4f5e9da 669 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 527 547 9.5E-48 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CU254_RS09810 bb222b2d96f5d18a9cfaa9eaf4f5e9da 669 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 582 597 9.5E-48 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CU254_RS09810 bb222b2d96f5d18a9cfaa9eaf4f5e9da 669 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 497 516 9.5E-48 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CU254_RS09810 bb222b2d96f5d18a9cfaa9eaf4f5e9da 669 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 442 460 9.5E-48 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CU254_RS09810 bb222b2d96f5d18a9cfaa9eaf4f5e9da 669 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 469 493 9.5E-48 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CU254_RS04570 6f35464759ae971e4e7ba322e757f791 173 TIGRFAM TIGR02241 TIGR02241: conserved hypothetical phage tail region protein 10 157 1.3E-38 T 28-03-2018 IPR011747 Conserved hypothetical protein CHP02241 CU254_RS04570 6f35464759ae971e4e7ba322e757f791 173 Pfam PF06841 T4-like virus tail tube protein gp19 13 156 1.0E-37 T 28-03-2018 IPR010667 Bacteriophage T4, Gp19, tail tube GO:0005198 CU254_RS37235 467ed5fbecacefabf06c65daa8d120be 125 Pfam PF12680 SnoaL-like domain 11 88 3.2E-14 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CU254_RS37235 467ed5fbecacefabf06c65daa8d120be 125 Gene3D G3DSA:3.10.450.50 1 123 1.1E-19 T 28-03-2018 CU254_RS37235 467ed5fbecacefabf06c65daa8d120be 125 SUPERFAMILY SSF54427 5 104 9.76E-20 T 28-03-2018 IPR032710 NTF2-like domain CU254_RS07705 cbb4e5a8c44196ca0a74a201de1dfaa2 553 PIRSF PIRSF001294 4 553 2.7E-211 T 28-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CU254_RS07705 cbb4e5a8c44196ca0a74a201de1dfaa2 553 TIGRFAM TIGR00680 kdpA: K+-transporting ATPase, A subunit 5 552 1.9E-200 T 28-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CU254_RS07705 cbb4e5a8c44196ca0a74a201de1dfaa2 553 Hamap MF_00275 Potassium-transporting ATPase potassium-binding subunit [kdpA]. 4 553 31.574 T 28-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CU254_RS07705 cbb4e5a8c44196ca0a74a201de1dfaa2 553 Pfam PF03814 Potassium-transporting ATPase A subunit 13 552 2.6E-218 T 28-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CU254_RS10000 7e181a269cb0d45985fd3d8e65e44385 412 Pfam PF12897 Alanine-glyoxylate amino-transferase 8 410 4.9E-181 T 28-03-2018 IPR024551 Aminotransferase, putative CU254_RS10000 7e181a269cb0d45985fd3d8e65e44385 412 Gene3D G3DSA:3.90.1150.10 284 407 5.4E-18 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS10000 7e181a269cb0d45985fd3d8e65e44385 412 SUPERFAMILY SSF53383 51 404 9.92E-52 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS10000 7e181a269cb0d45985fd3d8e65e44385 412 Gene3D G3DSA:3.40.640.10 51 283 2.0E-33 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS37175 a12cca649f68ec9057bdf66aec32e440 505 SUPERFAMILY SSF51735 9 191 5.42E-48 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS37175 a12cca649f68ec9057bdf66aec32e440 505 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 11 189 2.7E-52 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CU254_RS37175 a12cca649f68ec9057bdf66aec32e440 505 SUPERFAMILY SSF48179 410 491 1.79E-18 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CU254_RS37175 a12cca649f68ec9057bdf66aec32e440 505 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 192 289 2.8E-20 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CU254_RS37175 a12cca649f68ec9057bdf66aec32e440 505 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 410 491 1.9E-17 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CU254_RS37175 a12cca649f68ec9057bdf66aec32e440 505 Gene3D G3DSA:1.10.1040.10 192 296 7.7E-21 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CU254_RS37175 a12cca649f68ec9057bdf66aec32e440 505 Gene3D G3DSA:1.10.1040.10 406 498 4.3E-19 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CU254_RS37175 a12cca649f68ec9057bdf66aec32e440 505 Gene3D G3DSA:3.40.50.720 5 191 3.2E-43 T 28-03-2018 CU254_RS37175 a12cca649f68ec9057bdf66aec32e440 505 SUPERFAMILY SSF48179 191 306 8.5E-25 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CU254_RS01670 10d611e0700ab34ad635f566078df49a 313 Gene3D G3DSA:3.40.630.30 142 302 4.2E-22 T 28-03-2018 CU254_RS01670 10d611e0700ab34ad635f566078df49a 313 Pfam PF00583 Acetyltransferase (GNAT) family 197 297 6.0E-12 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS01670 10d611e0700ab34ad635f566078df49a 313 SUPERFAMILY SSF55729 118 301 8.75E-22 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS40640 338c90416936d450b6c6aa7cce9e5ee8 569 Gene3D G3DSA:3.40.630.30 342 534 4.1E-10 T 28-03-2018 CU254_RS40640 338c90416936d450b6c6aa7cce9e5ee8 569 Pfam PF16995 Transmembrane region of lysyl-tRNA synthetase 24 171 1.7E-7 T 28-03-2018 IPR031553 Lysyl-tRNA synthetase, N-terminal transmembrane region KEGG: 00970+6.1.1.6 CU254_RS40640 338c90416936d450b6c6aa7cce9e5ee8 569 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 243 537 1.0E-92 T 28-03-2018 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal CU254_RS28030 af5ee8782694f044e5a1e13ddd9e2a5a 148 Gene3D G3DSA:3.40.630.30 1 130 5.7E-17 T 28-03-2018 CU254_RS28030 af5ee8782694f044e5a1e13ddd9e2a5a 148 Pfam PF13673 Acetyltransferase (GNAT) domain 27 105 2.0E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS28030 af5ee8782694f044e5a1e13ddd9e2a5a 148 SUPERFAMILY SSF55729 16 110 2.66E-18 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS23725 9cf59bf721a76efd790c0685238b92e9 390 Gene3D G3DSA:2.60.40.1220 42 132 9.5E-4 T 28-03-2018 CU254_RS23725 9cf59bf721a76efd790c0685238b92e9 390 SUPERFAMILY SSF141523 242 363 3.66E-28 T 28-03-2018 CU254_RS23725 9cf59bf721a76efd790c0685238b92e9 390 Pfam PF03734 L,D-transpeptidase catalytic domain 243 363 2.5E-16 T 28-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CU254_RS23725 9cf59bf721a76efd790c0685238b92e9 390 Gene3D G3DSA:2.40.440.10 239 364 1.0E-25 T 28-03-2018 CU254_RS16350 65a8a76fd88b154ae5021ba2cedafd9d 392 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 6 123 9.7E-19 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CU254_RS16350 65a8a76fd88b154ae5021ba2cedafd9d 392 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 138 208 1.2E-8 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CU254_RS16350 65a8a76fd88b154ae5021ba2cedafd9d 392 SUPERFAMILY SSF51735 4 152 3.21E-33 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS16350 65a8a76fd88b154ae5021ba2cedafd9d 392 Gene3D G3DSA:3.30.360.10 144 381 4.0E-38 T 28-03-2018 CU254_RS16350 65a8a76fd88b154ae5021ba2cedafd9d 392 SUPERFAMILY SSF55347 131 312 1.57E-23 T 28-03-2018 CU254_RS16350 65a8a76fd88b154ae5021ba2cedafd9d 392 Gene3D G3DSA:3.40.50.720 1 143 1.3E-28 T 28-03-2018 CU254_RS17905 b00046b21c66de64c2b8dbea10eaa60e 261 SUPERFAMILY SSF140459 12 160 2.59E-8 T 28-03-2018 CU254_RS17905 b00046b21c66de64c2b8dbea10eaa60e 261 Gene3D G3DSA:1.10.287.850 9 99 1.0E-8 T 28-03-2018 CU254_RS41160 af5904c64984baa1b22c88f2cda25e40 236 Gene3D G3DSA:3.40.50.300 54 158 2.9E-5 T 28-03-2018 CU254_RS34960 bed3e43de4827c4044a3d5405a476783 573 ProSitePatterns PS00145 Urease active site. 324 340 - T 28-03-2018 IPR017950 Urease active site GO:0009039 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CU254_RS34960 bed3e43de4827c4044a3d5405a476783 573 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 302 319 1.6E-33 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CU254_RS34960 bed3e43de4827c4044a3d5405a476783 573 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 341 357 1.6E-33 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CU254_RS34960 bed3e43de4827c4044a3d5405a476783 573 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 407 422 1.6E-33 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CU254_RS34960 bed3e43de4827c4044a3d5405a476783 573 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 433 446 1.6E-33 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CU254_RS34960 bed3e43de4827c4044a3d5405a476783 573 Gene3D G3DSA:3.20.20.140 150 427 1.0E-151 T 28-03-2018 CU254_RS34960 bed3e43de4827c4044a3d5405a476783 573 Gene3D G3DSA:3.20.20.140 428 559 1.3E-41 T 28-03-2018 CU254_RS34960 bed3e43de4827c4044a3d5405a476783 573 ProSitePatterns PS01120 Urease nickel ligands signature. 134 147 - T 28-03-2018 IPR029754 Urease nickel binding site GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CU254_RS34960 bed3e43de4827c4044a3d5405a476783 573 Gene3D G3DSA:2.30.40.10 69 149 2.0E-16 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS34960 bed3e43de4827c4044a3d5405a476783 573 SUPERFAMILY SSF51338 1 183 4.54E-57 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS34960 bed3e43de4827c4044a3d5405a476783 573 Pfam PF01979 Amidohydrolase family 132 455 2.0E-65 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CU254_RS34960 bed3e43de4827c4044a3d5405a476783 573 Hamap MF_01953 Urease subunit alpha [ureC]. 2 573 54.993 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CU254_RS34960 bed3e43de4827c4044a3d5405a476783 573 SUPERFAMILY SSF51556 487 573 2.5E-182 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS34960 bed3e43de4827c4044a3d5405a476783 573 SUPERFAMILY SSF51556 136 438 2.5E-182 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS34960 bed3e43de4827c4044a3d5405a476783 573 Pfam PF00449 Urease alpha-subunit, N-terminal domain 3 125 6.2E-52 T 28-03-2018 IPR011612 Urease alpha-subunit, N-terminal domain KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CU254_RS34960 bed3e43de4827c4044a3d5405a476783 573 SUPERFAMILY SSF51338 415 485 7.05E-10 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS34960 bed3e43de4827c4044a3d5405a476783 573 TIGRFAM TIGR01792 urease_alph: urease, alpha subunit 3 573 1.9E-267 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CU254_RS11405 1c6aab89890f143654d8270506e47275 312 Gene3D G3DSA:1.10.10.60 257 311 8.0E-11 T 28-03-2018 CU254_RS11405 1c6aab89890f143654d8270506e47275 312 Pfam PF12852 Cupin 2 185 1.0E-37 T 28-03-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain CU254_RS11405 1c6aab89890f143654d8270506e47275 312 SUPERFAMILY SSF46689 200 251 4.08E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS11405 1c6aab89890f143654d8270506e47275 312 Gene3D G3DSA:1.10.10.60 3 256 1.0E-11 T 28-03-2018 CU254_RS11405 1c6aab89890f143654d8270506e47275 312 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 270 285 9.3E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CU254_RS11405 1c6aab89890f143654d8270506e47275 312 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 285 301 9.3E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CU254_RS11405 1c6aab89890f143654d8270506e47275 312 SMART SM00342 217 301 9.2E-28 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS11405 1c6aab89890f143654d8270506e47275 312 Pfam PF12833 Helix-turn-helix domain 223 302 2.9E-22 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS11405 1c6aab89890f143654d8270506e47275 312 SUPERFAMILY SSF46689 253 303 2.33E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS06875 da88e878ebe818e38ab757fd377c8112 186 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 58 1.4E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS06875 da88e878ebe818e38ab757fd377c8112 186 Gene3D G3DSA:1.10.357.10 60 186 6.2E-11 T 28-03-2018 CU254_RS06875 da88e878ebe818e38ab757fd377c8112 186 SUPERFAMILY SSF46689 8 68 1.69E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS06875 da88e878ebe818e38ab757fd377c8112 186 Gene3D G3DSA:1.10.10.60 4 59 9.5E-13 T 28-03-2018 CU254_RS06875 da88e878ebe818e38ab757fd377c8112 186 SUPERFAMILY SSF48498 80 181 3.38E-5 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS01700 ecb6c1cb77416124ca6d37ad46f673bc 146 Pfam PF01575 MaoC like domain 24 110 3.3E-25 T 28-03-2018 IPR002539 MaoC-like domain CU254_RS01700 ecb6c1cb77416124ca6d37ad46f673bc 146 SUPERFAMILY SSF54637 15 137 1.55E-26 T 28-03-2018 IPR029069 HotDog domain CU254_RS01700 ecb6c1cb77416124ca6d37ad46f673bc 146 Gene3D G3DSA:3.10.129.10 12 144 2.6E-33 T 28-03-2018 CU254_RS22555 abc875e88dfc4f4750bc98567e86ea5f 377 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 4 29 0.0013 T 28-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal CU254_RS22555 abc875e88dfc4f4750bc98567e86ea5f 377 Gene3D G3DSA:2.130.10.10 311 375 2.4E-5 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CU254_RS22555 abc875e88dfc4f4750bc98567e86ea5f 377 Pfam PF10282 Lactonase, 7-bladed beta-propeller 38 375 4.6E-98 T 28-03-2018 IPR019405 Lactonase, 7-bladed beta propeller CU254_RS22555 abc875e88dfc4f4750bc98567e86ea5f 377 Gene3D G3DSA:2.120.10.30 34 167 1.5E-9 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CU254_RS22555 abc875e88dfc4f4750bc98567e86ea5f 377 Gene3D G3DSA:2.130.10.10 168 310 3.3E-32 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CU254_RS22555 abc875e88dfc4f4750bc98567e86ea5f 377 SUPERFAMILY SSF51004 66 357 1.44E-48 T 28-03-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain CU254_RS37460 06022c57a749bba8d107a5a85c4a6753 300 Pfam PF11209 Protein of unknown function (DUF2993) 42 285 2.4E-44 T 28-03-2018 IPR021373 Protein of unknown function DUF2993 CU254_RS31880 4247121c1d5b1b0dbef26d9d5cf959ab 172 SUPERFAMILY SSF55729 2 138 2.03E-23 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS31880 4247121c1d5b1b0dbef26d9d5cf959ab 172 Gene3D G3DSA:3.40.630.30 1 167 2.3E-24 T 28-03-2018 CU254_RS31880 4247121c1d5b1b0dbef26d9d5cf959ab 172 Pfam PF00583 Acetyltransferase (GNAT) family 40 130 6.9E-12 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS09560 adf0792feddd759f2cdbee309f2cad92 207 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 7 205 3.8E-73 T 28-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 CU254_RS09560 adf0792feddd759f2cdbee309f2cad92 207 Pfam PF01081 KDPG and KHG aldolase 8 199 1.9E-67 T 28-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 CU254_RS09560 adf0792feddd759f2cdbee309f2cad92 207 ProSitePatterns PS00159 KDPG and KHG aldolases active site. 36 45 - T 28-03-2018 IPR031337 KDPG/KHG aldolase, active site 1 KEGG: 00030+4.1.2.14|KEGG: 00330+4.1.3.16|KEGG: 00630+4.1.3.16|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 CU254_RS09560 adf0792feddd759f2cdbee309f2cad92 207 SUPERFAMILY SSF51569 6 205 3.48E-65 T 28-03-2018 CU254_RS09560 adf0792feddd759f2cdbee309f2cad92 207 Gene3D G3DSA:3.20.20.70 5 206 1.1E-32 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS09560 adf0792feddd759f2cdbee309f2cad92 207 ProSitePatterns PS00160 KDPG and KHG aldolases Schiff-base forming residue. 124 137 - T 28-03-2018 IPR031338 KDPG/KHG aldolase, active site 2 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 CU254_RS39315 fc2bc6124336ad6c76ced85df276e440 158 Pfam PF12802 MarR family 45 102 2.9E-11 T 28-03-2018 CU254_RS39315 fc2bc6124336ad6c76ced85df276e440 158 SMART SM00347 39 138 6.0E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS39315 fc2bc6124336ad6c76ced85df276e440 158 Gene3D G3DSA:1.10.10.10 3 156 9.0E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS39315 fc2bc6124336ad6c76ced85df276e440 158 SUPERFAMILY SSF46785 16 153 1.05E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS13550 c7d11c3c22c307fb06ea033e2a3a34f1 166 Pfam PF10914 Protein of unknown function (DUF2781) 14 156 1.5E-22 T 28-03-2018 CU254_RS20275 4c6d89537f8f0889bafedf131e34624e 244 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 241 4.0E-56 T 28-03-2018 CU254_RS20275 4c6d89537f8f0889bafedf131e34624e 244 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 185 0.0024 T 28-03-2018 CU254_RS20275 4c6d89537f8f0889bafedf131e34624e 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 6.3E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS20275 4c6d89537f8f0889bafedf131e34624e 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 225 6.3E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS20275 4c6d89537f8f0889bafedf131e34624e 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 6.3E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS20275 4c6d89537f8f0889bafedf131e34624e 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 6.3E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS20275 4c6d89537f8f0889bafedf131e34624e 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 6.3E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS20275 4c6d89537f8f0889bafedf131e34624e 244 SUPERFAMILY SSF51735 6 241 1.19E-72 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS20275 4c6d89537f8f0889bafedf131e34624e 244 Gene3D G3DSA:3.40.50.720 1 44 4.7E-11 T 28-03-2018 CU254_RS20275 4c6d89537f8f0889bafedf131e34624e 244 Gene3D G3DSA:3.40.50.720 45 243 2.2E-55 T 28-03-2018 CU254_RS20275 4c6d89537f8f0889bafedf131e34624e 244 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS20275 4c6d89537f8f0889bafedf131e34624e 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 9.8E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS20275 4c6d89537f8f0889bafedf131e34624e 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 9.8E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS32965 1f20e39ec28bc8856ce42d1f08f244ba 101 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 12 98 2.1E-11 T 28-03-2018 IPR022536 ESX-1 secretion-associated protein EspC GO:0009306 CU254_RS32965 1f20e39ec28bc8856ce42d1f08f244ba 101 Gene3D G3DSA:1.10.287.1060 7 101 1.8E-6 T 28-03-2018 CU254_RS16185 3a56dd3af923f745b1adb2fa4a487737 268 Pfam PF00582 Universal stress protein family 149 268 3.6E-13 T 28-03-2018 IPR006016 UspA GO:0006950 CU254_RS16185 3a56dd3af923f745b1adb2fa4a487737 268 Pfam PF00582 Universal stress protein family 3 140 4.8E-20 T 28-03-2018 IPR006016 UspA GO:0006950 CU254_RS16185 3a56dd3af923f745b1adb2fa4a487737 268 PRINTS PR01438 Universal stress protein signature 118 140 3.1E-11 T 28-03-2018 IPR006015 Universal stress protein A CU254_RS16185 3a56dd3af923f745b1adb2fa4a487737 268 PRINTS PR01438 Universal stress protein signature 100 112 3.1E-11 T 28-03-2018 IPR006015 Universal stress protein A CU254_RS16185 3a56dd3af923f745b1adb2fa4a487737 268 PRINTS PR01438 Universal stress protein signature 2 20 3.1E-11 T 28-03-2018 IPR006015 Universal stress protein A CU254_RS16185 3a56dd3af923f745b1adb2fa4a487737 268 SUPERFAMILY SSF52402 148 268 1.0E-17 T 28-03-2018 CU254_RS16185 3a56dd3af923f745b1adb2fa4a487737 268 Gene3D G3DSA:3.40.50.620 1 140 2.4E-25 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS16185 3a56dd3af923f745b1adb2fa4a487737 268 SUPERFAMILY SSF52402 3 142 1.76E-23 T 28-03-2018 CU254_RS16185 3a56dd3af923f745b1adb2fa4a487737 268 Gene3D G3DSA:3.40.50.620 142 268 2.1E-20 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS20210 c33f1846d364294b2fecb647884d289f 193 Pfam PF13411 MerR HTH family regulatory protein 38 104 3.5E-14 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS20210 c33f1846d364294b2fecb647884d289f 193 Gene3D G3DSA:1.10.1660.10 35 111 7.3E-15 T 28-03-2018 CU254_RS20210 c33f1846d364294b2fecb647884d289f 193 SUPERFAMILY SSF46955 38 111 1.05E-13 T 28-03-2018 IPR009061 Putative DNA-binding domain CU254_RS20210 c33f1846d364294b2fecb647884d289f 193 SMART SM00422 35 107 3.6E-19 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS09030 a2ce3e0f7c294565ee1d0ce61aadc9ec 127 Gene3D G3DSA:1.10.287.1060 7 102 1.7E-5 T 28-03-2018 CU254_RS06935 5a5ddf6317d99f4503ba560115660611 357 Gene3D G3DSA:1.10.3470.10 12 352 3.2E-70 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CU254_RS06935 5a5ddf6317d99f4503ba560115660611 357 SUPERFAMILY SSF81345 11 350 2.48E-76 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CU254_RS06935 5a5ddf6317d99f4503ba560115660611 357 Pfam PF01032 FecCD transport family 29 349 2.0E-88 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CU254_RS22310 33316d39e7ab55e27c488c49e482f6da 210 Gene3D G3DSA:3.90.79.10 2 187 5.1E-34 T 28-03-2018 CU254_RS22310 33316d39e7ab55e27c488c49e482f6da 210 Pfam PF00293 NUDIX domain 46 159 1.1E-14 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CU254_RS22310 33316d39e7ab55e27c488c49e482f6da 210 SUPERFAMILY SSF55811 13 179 5.35E-43 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CU254_RS30615 966cf5b0713396133ea6bd281aa6239f 289 SUPERFAMILY SSF51717 10 279 3.92E-77 T 28-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CU254_RS30615 966cf5b0713396133ea6bd281aa6239f 289 Gene3D G3DSA:3.20.20.20 6 289 6.9E-83 T 28-03-2018 CU254_RS30615 966cf5b0713396133ea6bd281aa6239f 289 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 20 35 - T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CU254_RS30615 966cf5b0713396133ea6bd281aa6239f 289 Pfam PF00809 Pterin binding enzyme 21 261 8.5E-62 T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CU254_RS30615 966cf5b0713396133ea6bd281aa6239f 289 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 20 275 2.2E-77 T 28-03-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 CU254_RS14150 269c95f895ae2fd956501c93c0915114 419 SUPERFAMILY SSF103473 8 405 4.32E-63 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS14150 269c95f895ae2fd956501c93c0915114 419 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 15 392 2.4E-95 T 28-03-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 CU254_RS14150 269c95f895ae2fd956501c93c0915114 419 Gene3D G3DSA:1.20.1250.20 204 412 7.1E-19 T 28-03-2018 CU254_RS14150 269c95f895ae2fd956501c93c0915114 419 ProSitePatterns PS00216 Sugar transport proteins signature 1. 70 87 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CU254_RS14150 269c95f895ae2fd956501c93c0915114 419 Gene3D G3DSA:1.20.1250.20 12 201 3.1E-29 T 28-03-2018 CU254_RS14150 269c95f895ae2fd956501c93c0915114 419 Pfam PF07690 Major Facilitator Superfamily 23 365 3.9E-42 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS26140 35899db41d36468f509ae4ebc37b673c 476 Gene3D G3DSA:3.30.1490.20 342 451 0.0026 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CU254_RS26140 35899db41d36468f509ae4ebc37b673c 476 SUPERFAMILY SSF56059 61 197 1.84E-28 T 28-03-2018 CU254_RS26140 35899db41d36468f509ae4ebc37b673c 476 SUPERFAMILY SSF56059 303 444 1.84E-28 T 28-03-2018 CU254_RS26140 35899db41d36468f509ae4ebc37b673c 476 Gene3D G3DSA:3.40.50.261 168 305 0.0013 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CU254_RS26140 35899db41d36468f509ae4ebc37b673c 476 Pfam PF03738 Glutathionylspermidine synthase preATP-grasp 68 443 3.9E-13 T 28-03-2018 IPR005494 Glutathionylspermidine synthase, pre-ATP-grasp-like domain CU254_RS25925 3102184df4462778d07e0525e9c9a069 207 Pfam PF01810 LysE type translocator 16 204 1.2E-27 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CU254_RS34520 a8445342f86c9fb8bb8fdb5b88650308 324 Gene3D G3DSA:3.40.50.720 156 262 8.7E-17 T 28-03-2018 CU254_RS34520 a8445342f86c9fb8bb8fdb5b88650308 324 SUPERFAMILY SSF50129 6 155 6.86E-13 T 28-03-2018 IPR011032 GroES-like CU254_RS34520 a8445342f86c9fb8bb8fdb5b88650308 324 Gene3D G3DSA:3.90.180.10 2 155 1.0E-14 T 28-03-2018 CU254_RS34520 a8445342f86c9fb8bb8fdb5b88650308 324 SUPERFAMILY SSF51735 121 268 4.26E-17 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS25270 d2dce5a5b312d62c40408452da0aed09 344 Pfam PF02126 Phosphotriesterase family 11 343 8.3E-47 T 28-03-2018 IPR001559 Phosphotriesterase GO:0008270|GO:0009056 CU254_RS25270 d2dce5a5b312d62c40408452da0aed09 344 Gene3D G3DSA:3.20.20.140 1 344 2.0E-48 T 28-03-2018 CU254_RS25270 d2dce5a5b312d62c40408452da0aed09 344 SUPERFAMILY SSF51556 68 343 2.31E-65 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS25270 d2dce5a5b312d62c40408452da0aed09 344 SUPERFAMILY SSF51556 4 41 2.31E-65 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS08875 a2c44e56ee9f281e89b6dbf6ba3b117b 350 Pfam PF00591 Glycosyl transferase family, a/b domain 82 335 2.4E-83 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CU254_RS08875 a2c44e56ee9f281e89b6dbf6ba3b117b 350 Gene3D G3DSA:3.40.1030.10 81 349 1.2E-97 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CU254_RS08875 a2c44e56ee9f281e89b6dbf6ba3b117b 350 Gene3D G3DSA:1.20.970.10 5 78 1.5E-24 T 28-03-2018 CU254_RS08875 a2c44e56ee9f281e89b6dbf6ba3b117b 350 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 16 344 4.5E-116 T 28-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 CU254_RS08875 a2c44e56ee9f281e89b6dbf6ba3b117b 350 SUPERFAMILY SSF52418 82 346 1.2E-80 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CU254_RS08875 a2c44e56ee9f281e89b6dbf6ba3b117b 350 SUPERFAMILY SSF47648 11 77 2.49E-19 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CU254_RS08875 a2c44e56ee9f281e89b6dbf6ba3b117b 350 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 13 345 35.174 T 28-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 CU254_RS08875 a2c44e56ee9f281e89b6dbf6ba3b117b 350 Pfam PF02885 Glycosyl transferase family, helical bundle domain 14 74 3.5E-20 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CU254_RS17405 1f1862e70afb2d8b83ceb1e43cb34009 441 SUPERFAMILY SSF111283 9 440 7.98E-61 T 28-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 CU254_RS17405 1f1862e70afb2d8b83ceb1e43cb34009 441 Gene3D G3DSA:3.30.2290.10 1 197 7.4E-27 T 28-03-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal domain CU254_RS17405 1f1862e70afb2d8b83ceb1e43cb34009 441 Pfam PF01523 Putative modulator of DNA gyrase 21 309 5.3E-31 T 28-03-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 CU254_RS05050 0cbeb61acce33b229f80ee8b80675e66 361 SUPERFAMILY SSF51679 1 334 8.51E-72 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS05050 0cbeb61acce33b229f80ee8b80675e66 361 Pfam PF00296 Luciferase-like monooxygenase 1 295 8.0E-55 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS05050 0cbeb61acce33b229f80ee8b80675e66 361 TIGRFAM TIGR04036 LLM_CE1758_fam: putative luciferase-like monooxygenase, FMN-dependent, CE1758 family 1 355 2.0E-215 T 28-03-2018 IPR023934 Luciferase-like monooxygenase, FMN-dependent, putative CU254_RS05050 0cbeb61acce33b229f80ee8b80675e66 361 Gene3D G3DSA:3.20.20.30 1 346 1.6E-68 T 28-03-2018 CU254_RS11820 47c5f13beb7fd428173bf2f639c47072 433 Pfam PF00266 Aminotransferase class-V 38 418 5.4E-138 T 28-03-2018 IPR000192 Aminotransferase class V domain CU254_RS11820 47c5f13beb7fd428173bf2f639c47072 433 Gene3D G3DSA:3.90.1150.10 305 425 7.5E-41 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS11820 47c5f13beb7fd428173bf2f639c47072 433 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 239 258 - T 28-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CU254_RS11820 47c5f13beb7fd428173bf2f639c47072 433 Gene3D G3DSA:3.40.640.10 50 304 3.9E-59 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS11820 47c5f13beb7fd428173bf2f639c47072 433 SUPERFAMILY SSF53383 16 425 3.35E-121 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS11820 47c5f13beb7fd428173bf2f639c47072 433 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 19 430 7.2E-174 T 28-03-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CU254_RS26665 11963347d95bc27b18b8f8253e911ebb 490 PIRSF PIRSF006060 15 489 2.8E-86 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CU254_RS26665 11963347d95bc27b18b8f8253e911ebb 490 Pfam PF13520 Amino acid permease 36 446 1.1E-56 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CU254_RS04000 8243fa5b71706bfe2fec2dceda40d840 393 SMART SM00450 291 388 1.6E-26 T 28-03-2018 IPR001763 Rhodanese-like domain CU254_RS04000 8243fa5b71706bfe2fec2dceda40d840 393 SUPERFAMILY SSF69572 10 360 3.79E-96 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CU254_RS04000 8243fa5b71706bfe2fec2dceda40d840 393 Pfam PF00581 Rhodanese-like domain 291 384 2.3E-13 T 28-03-2018 IPR001763 Rhodanese-like domain CU254_RS04000 8243fa5b71706bfe2fec2dceda40d840 393 Gene3D G3DSA:3.40.250.10 269 390 2.9E-26 T 28-03-2018 IPR001763 Rhodanese-like domain CU254_RS04000 8243fa5b71706bfe2fec2dceda40d840 393 Pfam PF00899 ThiF family 24 260 2.4E-60 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CU254_RS04000 8243fa5b71706bfe2fec2dceda40d840 393 Gene3D G3DSA:3.40.50.720 13 263 3.0E-68 T 28-03-2018 CU254_RS28365 6edd8793d652eaa86dee280aee8e52c7 472 Pfam PF07690 Major Facilitator Superfamily 17 408 3.0E-61 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS28365 6edd8793d652eaa86dee280aee8e52c7 472 SUPERFAMILY SSF103473 247 447 5.75E-72 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS28365 6edd8793d652eaa86dee280aee8e52c7 472 SUPERFAMILY SSF103473 7 199 5.75E-72 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS28365 6edd8793d652eaa86dee280aee8e52c7 472 Gene3D G3DSA:1.20.1250.20 251 463 1.7E-26 T 28-03-2018 CU254_RS28365 6edd8793d652eaa86dee280aee8e52c7 472 PRINTS PR01036 Tetracycline resistance protein TetB signature 15 39 3.2E-14 T 28-03-2018 CU254_RS28365 6edd8793d652eaa86dee280aee8e52c7 472 PRINTS PR01036 Tetracycline resistance protein TetB signature 137 161 3.2E-14 T 28-03-2018 CU254_RS28365 6edd8793d652eaa86dee280aee8e52c7 472 PRINTS PR01036 Tetracycline resistance protein TetB signature 337 357 3.2E-14 T 28-03-2018 CU254_RS28365 6edd8793d652eaa86dee280aee8e52c7 472 PRINTS PR01036 Tetracycline resistance protein TetB signature 75 97 3.2E-14 T 28-03-2018 CU254_RS28365 6edd8793d652eaa86dee280aee8e52c7 472 PRINTS PR01036 Tetracycline resistance protein TetB signature 301 325 3.2E-14 T 28-03-2018 CU254_RS28365 6edd8793d652eaa86dee280aee8e52c7 472 PRINTS PR01036 Tetracycline resistance protein TetB signature 399 418 3.2E-14 T 28-03-2018 CU254_RS28365 6edd8793d652eaa86dee280aee8e52c7 472 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 16 417 8.0E-89 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CU254_RS28365 6edd8793d652eaa86dee280aee8e52c7 472 Gene3D G3DSA:1.20.1250.20 5 200 9.2E-36 T 28-03-2018 CU254_RS39355 e41f55ed485f077ad1ece3b0a638d3db 792 Gene3D G3DSA:1.20.1580.10 107 373 2.2E-60 T 28-03-2018 CU254_RS39355 e41f55ed485f077ad1ece3b0a638d3db 792 Gene3D G3DSA:3.40.50.300 3 73 0.095 T 28-03-2018 CU254_RS39355 e41f55ed485f077ad1ece3b0a638d3db 792 SUPERFAMILY SSF52540 20 165 5.17E-36 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS39355 e41f55ed485f077ad1ece3b0a638d3db 792 SUPERFAMILY SSF52540 313 455 5.17E-36 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS39355 e41f55ed485f077ad1ece3b0a638d3db 792 Gene3D G3DSA:3.40.50.300 490 791 8.0E-57 T 28-03-2018 CU254_RS39355 e41f55ed485f077ad1ece3b0a638d3db 792 SUPERFAMILY SSF52540 495 764 9.87E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS39355 e41f55ed485f077ad1ece3b0a638d3db 792 SMART SM00382 513 757 0.23 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS39355 e41f55ed485f077ad1ece3b0a638d3db 792 SMART SM00382 39 450 6.4 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS39355 e41f55ed485f077ad1ece3b0a638d3db 792 Pfam PF00005 ABC transporter 504 711 4.1E-12 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS24440 528f3836fdd3356c339dbead01c5a1db 492 Gene3D G3DSA:3.30.70.1450 393 477 6.3E-12 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CU254_RS24440 528f3836fdd3356c339dbead01c5a1db 492 Pfam PF00999 Sodium/hydrogen exchanger family 13 379 2.1E-47 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CU254_RS24440 528f3836fdd3356c339dbead01c5a1db 492 Pfam PF02080 TrkA-C domain 408 472 7.5E-9 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CU254_RS24440 528f3836fdd3356c339dbead01c5a1db 492 SUPERFAMILY SSF116726 402 473 3.92E-10 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CU254_RS10270 bc4b1f5fc5471949d4c0b9e1fd891f77 145 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 11 142 6.5E-30 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CU254_RS10270 bc4b1f5fc5471949d4c0b9e1fd891f77 145 Gene3D G3DSA:3.30.530.20 1 145 2.8E-31 T 28-03-2018 IPR023393 START-like domain CU254_RS10270 bc4b1f5fc5471949d4c0b9e1fd891f77 145 SUPERFAMILY SSF55961 2 143 1.12E-43 T 28-03-2018 CU254_RS30440 e8c4ee5bfe45551be540693f3c26260e 130 Gene3D G3DSA:1.10.1660.10 1 54 3.0E-23 T 28-03-2018 CU254_RS30440 e8c4ee5bfe45551be540693f3c26260e 130 Gene3D G3DSA:1.10.1660.10 55 129 4.0E-13 T 28-03-2018 CU254_RS30440 e8c4ee5bfe45551be540693f3c26260e 130 SMART SM00422 1 69 2.4E-22 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS30440 e8c4ee5bfe45551be540693f3c26260e 130 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 7.3E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS30440 e8c4ee5bfe45551be540693f3c26260e 130 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 7.3E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS30440 e8c4ee5bfe45551be540693f3c26260e 130 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 7.3E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS30440 e8c4ee5bfe45551be540693f3c26260e 130 SUPERFAMILY SSF46955 1 113 1.14E-26 T 28-03-2018 IPR009061 Putative DNA-binding domain CU254_RS30440 e8c4ee5bfe45551be540693f3c26260e 130 Pfam PF13411 MerR HTH family regulatory protein 1 61 3.6E-17 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS34265 a2c7f0dc159c135439581f7cb4370678 479 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 169 184 - T 28-03-2018 IPR019826 Carboxylesterase type B, active site CU254_RS34265 a2c7f0dc159c135439581f7cb4370678 479 SUPERFAMILY SSF53474 7 461 7.67E-94 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS34265 a2c7f0dc159c135439581f7cb4370678 479 Pfam PF00135 Carboxylesterase family 6 435 6.0E-75 T 28-03-2018 IPR002018 Carboxylesterase, type B CU254_RS34265 a2c7f0dc159c135439581f7cb4370678 479 Gene3D G3DSA:3.40.50.1820 2 473 2.4E-101 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS33870 2e7c83a7a68552cb7ab2282c2d4903c3 204 Gene3D G3DSA:3.20.20.80 2 197 1.9E-27 T 28-03-2018 CU254_RS33870 2e7c83a7a68552cb7ab2282c2d4903c3 204 Pfam PF01183 Glycosyl hydrolases family 25 17 184 1.9E-11 T 28-03-2018 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 CU254_RS33870 2e7c83a7a68552cb7ab2282c2d4903c3 204 SUPERFAMILY SSF51445 9 192 9.83E-20 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS11250 b0a661fcf24c5487b25ad2fac4f5117c 284 TIGRFAM TIGR03709 PPK2_rel_1: polyphosphate:nucleotide phosphotransferase, PPK2 family 31 273 2.1E-102 T 28-03-2018 IPR022300 Polyphosphate:nucleotide phosphotransferase, PPK2 GO:0006797|GO:0016776 CU254_RS11250 b0a661fcf24c5487b25ad2fac4f5117c 284 Gene3D G3DSA:3.40.50.300 3 280 2.9E-79 T 28-03-2018 CU254_RS11250 b0a661fcf24c5487b25ad2fac4f5117c 284 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 34 262 2.2E-68 T 28-03-2018 IPR022488 Polyphosphate kinase-2-related CU254_RS11250 b0a661fcf24c5487b25ad2fac4f5117c 284 PIRSF PIRSF028756 2 280 4.9E-72 T 28-03-2018 IPR016898 Polyphosphate kinase 2 CU254_RS11250 b0a661fcf24c5487b25ad2fac4f5117c 284 SUPERFAMILY SSF52540 68 243 1.15E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS00125 0efd04b95ea2cf7cced762b8aca91eef 178 Pfam PF04978 Protein of unknown function (DUF664) 28 174 3.2E-45 T 28-03-2018 IPR007061 Protein of unknown function DUF664 CU254_RS00125 0efd04b95ea2cf7cced762b8aca91eef 178 SUPERFAMILY SSF109854 7 173 3.21E-45 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CU254_RS00125 0efd04b95ea2cf7cced762b8aca91eef 178 Gene3D G3DSA:1.20.120.450 2 178 2.5E-35 T 28-03-2018 CU254_RS18940 55ea6514c7450e10f6d0d08f9f60938a 533 Gene3D G3DSA:3.20.20.140 166 459 2.4E-37 T 28-03-2018 CU254_RS18940 55ea6514c7450e10f6d0d08f9f60938a 533 SUPERFAMILY SSF51556 59 117 5.61E-32 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS18940 55ea6514c7450e10f6d0d08f9f60938a 533 SUPERFAMILY SSF51556 183 458 5.61E-32 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS18940 55ea6514c7450e10f6d0d08f9f60938a 533 Pfam PF07969 Amidohydrolase family 48 526 7.8E-83 T 28-03-2018 IPR013108 Amidohydrolase 3 CU254_RS18940 55ea6514c7450e10f6d0d08f9f60938a 533 SUPERFAMILY SSF51338 5 77 4.01E-16 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS18940 55ea6514c7450e10f6d0d08f9f60938a 533 Gene3D G3DSA:2.30.40.10 2 117 1.8E-19 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS11535 d157838b33fd2855367c1fcac31852e8 380 SUPERFAMILY SSF53448 34 223 3.0E-5 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS11535 d157838b33fd2855367c1fcac31852e8 380 Gene3D G3DSA:3.40.50.880 2 318 0.0016 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS36410 e9a7de92d9768d3744cf45bcb53eeae2 152 Gene3D G3DSA:3.10.50.30 81 152 3.2E-12 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CU254_RS36410 e9a7de92d9768d3744cf45bcb53eeae2 152 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 84 148 3.1E-9 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CU254_RS36410 e9a7de92d9768d3744cf45bcb53eeae2 152 Gene3D G3DSA:1.10.287.180 8 75 4.4E-7 T 28-03-2018 CU254_RS36410 e9a7de92d9768d3744cf45bcb53eeae2 152 SUPERFAMILY SSF54534 82 147 6.41E-8 T 28-03-2018 CU254_RS36410 e9a7de92d9768d3744cf45bcb53eeae2 152 PIRSF PIRSF006092 5 151 1.0E-13 T 28-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 CU254_RS26890 0723819b6968f006f243d5f3dcd4b6fc 136 SUPERFAMILY SSF54919 2 135 3.54E-53 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CU254_RS26890 0723819b6968f006f243d5f3dcd4b6fc 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 5 27 3.5E-42 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CU254_RS26890 0723819b6968f006f243d5f3dcd4b6fc 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 3.5E-42 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CU254_RS26890 0723819b6968f006f243d5f3dcd4b6fc 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 3.5E-42 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CU254_RS26890 0723819b6968f006f243d5f3dcd4b6fc 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 69 86 3.5E-42 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CU254_RS26890 0723819b6968f006f243d5f3dcd4b6fc 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 49 68 3.5E-42 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CU254_RS26890 0723819b6968f006f243d5f3dcd4b6fc 136 Pfam PF00334 Nucleoside diphosphate kinase 3 135 5.5E-52 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CU254_RS26890 0723819b6968f006f243d5f3dcd4b6fc 136 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 2 136 34.093 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CU254_RS26890 0723819b6968f006f243d5f3dcd4b6fc 136 Gene3D G3DSA:3.30.70.141 1 136 6.8E-50 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CU254_RS26890 0723819b6968f006f243d5f3dcd4b6fc 136 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 114 122 - T 28-03-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CU254_RS26890 0723819b6968f006f243d5f3dcd4b6fc 136 SMART SM00562 2 136 6.8E-72 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CU254_RS05235 350710dbccbabb9a080f0f9ae135e45f 251 SUPERFAMILY SSF51735 1 249 3.34E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS05235 350710dbccbabb9a080f0f9ae135e45f 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 247 3.1E-36 T 28-03-2018 CU254_RS05235 350710dbccbabb9a080f0f9ae135e45f 251 Gene3D G3DSA:3.40.50.720 2 251 2.2E-42 T 28-03-2018 CU254_RS05235 350710dbccbabb9a080f0f9ae135e45f 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 71 82 5.3E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS05235 350710dbccbabb9a080f0f9ae135e45f 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 5.3E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS05235 350710dbccbabb9a080f0f9ae135e45f 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 5.3E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS05235 350710dbccbabb9a080f0f9ae135e45f 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 5.3E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS22565 33c9b7439b23a75cdb85a06d2254e10b 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 96 301 1.1E-12 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS22565 33c9b7439b23a75cdb85a06d2254e10b 306 Gene3D G3DSA:1.10.3720.10 16 305 1.6E-43 T 28-03-2018 CU254_RS22565 33c9b7439b23a75cdb85a06d2254e10b 306 SUPERFAMILY SSF161098 11 302 3.14E-51 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS04390 707d49c32f2b61f54c145a98810796f7 283 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 270 5.2E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS04390 707d49c32f2b61f54c145a98810796f7 283 SUPERFAMILY SSF161098 21 272 1.7E-46 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS04390 707d49c32f2b61f54c145a98810796f7 283 Gene3D G3DSA:1.10.3720.10 12 279 1.5E-37 T 28-03-2018 CU254_RS05915 7131e969cc0d24487869bb6dcccca22e 508 SMART SM00641 27 133 8.3E-34 T 28-03-2018 IPR018077 Glycoside hydrolase, family 25 subgroup CU254_RS05915 7131e969cc0d24487869bb6dcccca22e 508 SUPERFAMILY SSF51445 27 229 4.63E-52 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS05915 7131e969cc0d24487869bb6dcccca22e 508 Gene3D G3DSA:3.20.20.80 10 240 6.8E-59 T 28-03-2018 CU254_RS05915 7131e969cc0d24487869bb6dcccca22e 508 ProSitePatterns PS00953 Glycosyl hydrolases family 25 active sites signature. 31 64 - T 28-03-2018 IPR008270 Glycoside hydrolase, family 25, active site GO:0003796|GO:0009253|GO:0016998 CU254_RS05915 7131e969cc0d24487869bb6dcccca22e 508 Pfam PF01183 Glycosyl hydrolases family 25 30 214 6.2E-38 T 28-03-2018 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 CU254_RS05915 7131e969cc0d24487869bb6dcccca22e 508 Pfam PF08310 LGFP repeat 414 469 3.7E-25 T 28-03-2018 IPR013207 LGFP CU254_RS05915 7131e969cc0d24487869bb6dcccca22e 508 Pfam PF08310 LGFP repeat 304 357 8.2E-24 T 28-03-2018 IPR013207 LGFP CU254_RS05915 7131e969cc0d24487869bb6dcccca22e 508 Pfam PF08310 LGFP repeat 358 413 7.4E-25 T 28-03-2018 IPR013207 LGFP CU254_RS05915 7131e969cc0d24487869bb6dcccca22e 508 Pfam PF08310 LGFP repeat 471 505 2.2E-6 T 28-03-2018 IPR013207 LGFP CU254_RS05915 7131e969cc0d24487869bb6dcccca22e 508 Pfam PF08310 LGFP repeat 252 302 1.1E-10 T 28-03-2018 IPR013207 LGFP CU254_RS24525 5228b224220b038a46787c54e7e35056 197 Gene3D G3DSA:1.10.10.10 107 196 1.6E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS24525 5228b224220b038a46787c54e7e35056 197 SUPERFAMILY SSF88946 15 108 1.73E-21 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS24525 5228b224220b038a46787c54e7e35056 197 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 33 193 2.2E-24 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS24525 5228b224220b038a46787c54e7e35056 197 SUPERFAMILY SSF88659 131 193 1.81E-15 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS24525 5228b224220b038a46787c54e7e35056 197 Gene3D G3DSA:1.10.1740.10 14 106 1.3E-20 T 28-03-2018 CU254_RS24525 5228b224220b038a46787c54e7e35056 197 Pfam PF08281 Sigma-70, region 4 137 189 3.4E-14 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS24525 5228b224220b038a46787c54e7e35056 197 Pfam PF04542 Sigma-70 region 2 37 104 7.7E-15 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS36065 081e4cf3059198ec7131e1fa0e0f2513 417 Pfam PF07690 Major Facilitator Superfamily 9 278 4.7E-22 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS36065 081e4cf3059198ec7131e1fa0e0f2513 417 SUPERFAMILY SSF103473 2 394 7.06E-50 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS36065 081e4cf3059198ec7131e1fa0e0f2513 417 Gene3D G3DSA:1.20.1250.20 194 416 2.8E-25 T 28-03-2018 CU254_RS36065 081e4cf3059198ec7131e1fa0e0f2513 417 Gene3D G3DSA:1.20.1250.20 1 190 5.3E-15 T 28-03-2018 CU254_RS08175 0f5810d68261db81b870664ae346684b 199 SUPERFAMILY SSF109854 4 135 2.14E-21 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CU254_RS08175 0f5810d68261db81b870664ae346684b 199 TIGRFAM TIGR03086 TIGR03086: TIGR03086 family protein 9 192 8.9E-39 T 28-03-2018 IPR017520 Conserved hypothetical protein CHP03086 CU254_RS08175 0f5810d68261db81b870664ae346684b 199 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 8 128 3.0E-14 T 28-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CU254_RS08175 0f5810d68261db81b870664ae346684b 199 Gene3D G3DSA:1.20.120.450 1 134 3.0E-21 T 28-03-2018 CU254_RS08175 0f5810d68261db81b870664ae346684b 199 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 8 162 1.2E-22 T 28-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CU254_RS30300 685f90d72ab486201aa4b754f53e237f 269 Pfam PF08241 Methyltransferase domain 49 143 2.4E-23 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CU254_RS30300 685f90d72ab486201aa4b754f53e237f 269 Gene3D G3DSA:3.40.50.150 2 235 3.6E-32 T 28-03-2018 CU254_RS30300 685f90d72ab486201aa4b754f53e237f 269 SUPERFAMILY SSF53335 27 214 2.41E-37 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS10055 88b5765ce3a03d936ef4c5c0e1432352 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 2.4E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS10055 88b5765ce3a03d936ef4c5c0e1432352 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 2.4E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS10055 88b5765ce3a03d936ef4c5c0e1432352 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 2.4E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS10055 88b5765ce3a03d936ef4c5c0e1432352 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 2.4E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS10055 88b5765ce3a03d936ef4c5c0e1432352 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 2.4E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS10055 88b5765ce3a03d936ef4c5c0e1432352 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 2.4E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS10055 88b5765ce3a03d936ef4c5c0e1432352 262 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 257 6.3E-47 T 28-03-2018 CU254_RS10055 88b5765ce3a03d936ef4c5c0e1432352 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 3.5E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS10055 88b5765ce3a03d936ef4c5c0e1432352 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 3.5E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS10055 88b5765ce3a03d936ef4c5c0e1432352 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 3.5E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS10055 88b5765ce3a03d936ef4c5c0e1432352 262 SUPERFAMILY SSF51735 7 258 4.21E-64 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS10055 88b5765ce3a03d936ef4c5c0e1432352 262 Gene3D G3DSA:3.40.50.720 46 261 8.5E-49 T 28-03-2018 CU254_RS10055 88b5765ce3a03d936ef4c5c0e1432352 262 Gene3D G3DSA:3.40.50.720 1 45 4.4E-9 T 28-03-2018 CU254_RS36385 f114b7e37b4214bbcee8515431c370dd 135 Pfam PF03795 YCII-related domain 17 107 1.2E-10 T 28-03-2018 IPR005545 YCII-related CU254_RS36385 f114b7e37b4214bbcee8515431c370dd 135 SUPERFAMILY SSF54909 21 123 1.96E-23 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS36385 f114b7e37b4214bbcee8515431c370dd 135 Gene3D G3DSA:3.30.70.1060 1 132 7.9E-43 T 28-03-2018 CU254_RS36550 b988d89db39fe250b8dca6bd04d0f950 273 Gene3D G3DSA:3.40.50.1000 12 255 2.8E-15 T 28-03-2018 IPR023214 HAD-like domain CU254_RS36550 b988d89db39fe250b8dca6bd04d0f950 273 Pfam PF12710 haloacid dehalogenase-like hydrolase 15 200 3.3E-34 T 28-03-2018 CU254_RS36550 b988d89db39fe250b8dca6bd04d0f950 273 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 14 212 1.7E-58 T 28-03-2018 IPR006385 HAD-superfamily hydrolase, subfamily IB, SerB1-like CU254_RS36550 b988d89db39fe250b8dca6bd04d0f950 273 SUPERFAMILY SSF56784 12 222 2.91E-25 T 28-03-2018 IPR023214 HAD-like domain CU254_RS36550 b988d89db39fe250b8dca6bd04d0f950 273 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 14 201 1.3E-16 T 28-03-2018 CU254_RS18305 21aed9db81a2f607ec4f37af9c879151 921 Gene3D G3DSA:3.40.50.300 8 208 1.2E-36 T 28-03-2018 CU254_RS18305 21aed9db81a2f607ec4f37af9c879151 921 SMART SM01142 745 921 1.3E-65 T 28-03-2018 IPR012961 ATP-dependent RNA helicase Ski2, C-terminal CU254_RS18305 21aed9db81a2f607ec4f37af9c879151 921 Pfam PF13234 rRNA-processing arch domain 493 593 6.1E-5 T 28-03-2018 IPR025696 rRNA-processing arch domain CU254_RS18305 21aed9db81a2f607ec4f37af9c879151 921 SMART SM00487 32 214 3.1E-32 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CU254_RS18305 21aed9db81a2f607ec4f37af9c879151 921 Pfam PF00271 Helicase conserved C-terminal domain 361 437 1.0E-4 T 28-03-2018 IPR001650 Helicase, C-terminal CU254_RS18305 21aed9db81a2f607ec4f37af9c879151 921 Pfam PF00270 DEAD/DEAH box helicase 39 185 1.1E-17 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CU254_RS18305 21aed9db81a2f607ec4f37af9c879151 921 SUPERFAMILY SSF52540 268 315 4.86E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS18305 21aed9db81a2f607ec4f37af9c879151 921 SUPERFAMILY SSF52540 357 450 4.86E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS18305 21aed9db81a2f607ec4f37af9c879151 921 SUPERFAMILY SSF52540 45 187 4.86E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS18305 21aed9db81a2f607ec4f37af9c879151 921 Gene3D G3DSA:3.40.50.300 279 576 4.6E-17 T 28-03-2018 CU254_RS18305 21aed9db81a2f607ec4f37af9c879151 921 SMART SM00490 347 437 1.0E-13 T 28-03-2018 IPR001650 Helicase, C-terminal CU254_RS18305 21aed9db81a2f607ec4f37af9c879151 921 Pfam PF08148 DSHCT (NUC185) domain 748 917 6.2E-39 T 28-03-2018 IPR012961 ATP-dependent RNA helicase Ski2, C-terminal CU254_RS23550 e7aed68c8c5e22d555034b3a479b0c66 480 Gene3D G3DSA:2.40.320.10 2 199 1.3E-22 T 28-03-2018 CU254_RS23550 e7aed68c8c5e22d555034b3a479b0c66 480 SMART SM00880 203 460 8.3E-49 T 28-03-2018 IPR007899 CHAD domain CU254_RS23550 e7aed68c8c5e22d555034b3a479b0c66 480 Pfam PF05235 CHAD domain 203 428 2.8E-43 T 28-03-2018 IPR007899 CHAD domain CU254_RS23550 e7aed68c8c5e22d555034b3a479b0c66 480 Pfam PF01928 CYTH domain 8 166 3.8E-6 T 28-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 CU254_RS23550 e7aed68c8c5e22d555034b3a479b0c66 480 SUPERFAMILY SSF55154 8 190 6.54E-29 T 28-03-2018 IPR033469 CYTH-like domain Reactome: R-HSA-196819 CU254_RS02840 bde674a489ea84a7d8bfec33a57db711 129 SUPERFAMILY SSF53927 1 128 9.68E-37 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CU254_RS02840 bde674a489ea84a7d8bfec33a57db711 129 Gene3D G3DSA:3.40.140.10 1 129 1.9E-36 T 28-03-2018 CU254_RS02840 bde674a489ea84a7d8bfec33a57db711 129 Pfam PF08211 Cytidine and deoxycytidylate deaminase zinc-binding region 7 57 1.3E-9 T 28-03-2018 IPR013171 Cytidine/deoxycytidylate deaminase, zinc-binding domain GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199 CU254_RS01490 6bd97d3165ba16b55a32567ae78597ed 344 SUPERFAMILY SSF55729 150 295 3.16E-19 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS01490 6bd97d3165ba16b55a32567ae78597ed 344 Gene3D G3DSA:3.40.630.30 94 328 2.2E-23 T 28-03-2018 CU254_RS01490 6bd97d3165ba16b55a32567ae78597ed 344 Pfam PF13480 Acetyltransferase (GNAT) domain 156 293 6.0E-34 T 28-03-2018 CU254_RS37675 ba451e5b0e8482158d278560a0c4bfcb 225 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 3 220 38.133 T 28-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CU254_RS37675 ba451e5b0e8482158d278560a0c4bfcb 225 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 4 220 8.5E-79 T 28-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CU254_RS37675 ba451e5b0e8482158d278560a0c4bfcb 225 SMART SM01211 2 222 8.7E-119 T 28-03-2018 CU254_RS37675 ba451e5b0e8482158d278560a0c4bfcb 225 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 4 207 3.7E-34 T 28-03-2018 CU254_RS37675 ba451e5b0e8482158d278560a0c4bfcb 225 Gene3D G3DSA:3.40.50.880 1 224 4.9E-36 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS37675 ba451e5b0e8482158d278560a0c4bfcb 225 PIRSF PIRSF001586 1 225 5.3E-78 T 28-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CU254_RS37675 ba451e5b0e8482158d278560a0c4bfcb 225 SUPERFAMILY SSF52317 3 221 5.73E-69 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS23540 311fc37b79727d1f74c9e9cb660dc8ef 266 Gene3D G3DSA:1.10.10.10 183 265 2.6E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS23540 311fc37b79727d1f74c9e9cb660dc8ef 266 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 35 258 1.2E-94 T 28-03-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS23540 311fc37b79727d1f74c9e9cb660dc8ef 266 PRINTS PR00046 Major sigma-70 factor signature 65 78 2.4E-7 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS23540 311fc37b79727d1f74c9e9cb660dc8ef 266 PRINTS PR00046 Major sigma-70 factor signature 211 223 2.4E-7 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS23540 311fc37b79727d1f74c9e9cb660dc8ef 266 PRINTS PR00046 Major sigma-70 factor signature 228 243 2.4E-7 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS23540 311fc37b79727d1f74c9e9cb660dc8ef 266 SUPERFAMILY SSF88659 114 191 5.23E-16 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS23540 311fc37b79727d1f74c9e9cb660dc8ef 266 Gene3D G3DSA:1.10.601.10 15 109 1.1E-19 T 28-03-2018 CU254_RS23540 311fc37b79727d1f74c9e9cb660dc8ef 266 Pfam PF04545 Sigma-70, region 4 207 256 9.1E-16 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS23540 311fc37b79727d1f74c9e9cb660dc8ef 266 SUPERFAMILY SSF88946 12 110 1.44E-27 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS23540 311fc37b79727d1f74c9e9cb660dc8ef 266 Gene3D G3DSA:1.10.10.10 111 163 6.6E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS23540 311fc37b79727d1f74c9e9cb660dc8ef 266 Pfam PF04539 Sigma-70 region 3 125 186 2.2E-11 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS23540 311fc37b79727d1f74c9e9cb660dc8ef 266 SUPERFAMILY SSF88659 177 259 2.06E-17 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS23540 311fc37b79727d1f74c9e9cb660dc8ef 266 Pfam PF04542 Sigma-70 region 2 41 110 1.2E-16 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS23540 311fc37b79727d1f74c9e9cb660dc8ef 266 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 37 258 3.2E-36 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS35275 326207364f76921ff539a6cf2e1b57d4 201 Gene3D G3DSA:3.40.50.300 10 197 3.9E-19 T 28-03-2018 CU254_RS35275 326207364f76921ff539a6cf2e1b57d4 201 SUPERFAMILY SSF52540 21 192 1.13E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS35275 326207364f76921ff539a6cf2e1b57d4 201 Pfam PF03029 Conserved hypothetical ATP binding protein 25 193 6.8E-27 T 28-03-2018 IPR004130 GPN-loop GTPase CU254_RS23995 72b48e6b767c1f0a8b251226621a3dee 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS23995 72b48e6b767c1f0a8b251226621a3dee 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.0E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23995 72b48e6b767c1f0a8b251226621a3dee 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.0E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23995 72b48e6b767c1f0a8b251226621a3dee 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.0E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23995 72b48e6b767c1f0a8b251226621a3dee 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 1.0E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23995 72b48e6b767c1f0a8b251226621a3dee 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 1.0E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23995 72b48e6b767c1f0a8b251226621a3dee 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 1.0E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23995 72b48e6b767c1f0a8b251226621a3dee 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 248 1.1E-49 T 28-03-2018 CU254_RS23995 72b48e6b767c1f0a8b251226621a3dee 253 Gene3D G3DSA:3.40.50.720 1 252 4.2E-60 T 28-03-2018 CU254_RS23995 72b48e6b767c1f0a8b251226621a3dee 253 SUPERFAMILY SSF51735 6 249 5.75E-68 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS22215 641602afb9570967620aad54e05a5e8f 762 SUPERFAMILY SSF48208 250 693 2.04E-35 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CU254_RS22215 641602afb9570967620aad54e05a5e8f 762 Gene3D G3DSA:1.50.10.10 208 630 7.1E-65 T 28-03-2018 CU254_RS22215 641602afb9570967620aad54e05a5e8f 762 Gene3D G3DSA:2.60.40.1180 631 740 3.7E-16 T 28-03-2018 CU254_RS33410 187f4e1bcc5f1fc8bb792b3dbd755f86 127 Gene3D G3DSA:3.10.180.10 1 124 3.4E-21 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS33410 187f4e1bcc5f1fc8bb792b3dbd755f86 127 SUPERFAMILY SSF54593 1 122 1.69E-15 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS26910 b5b8d3121576781d620e4dfa4bb56493 120 Pfam PF14017 Protein of unknown function (DUF4233) 5 107 5.5E-24 T 28-03-2018 IPR025327 Protein of unknown function DUF4233 CU254_RS31160 8ccdd74ccf2eede637d878c29087d887 194 SUPERFAMILY SSF52218 5 187 6.95E-44 T 28-03-2018 IPR029039 Flavoprotein-like domain CU254_RS31160 8ccdd74ccf2eede637d878c29087d887 194 Pfam PF03358 NADPH-dependent FMN reductase 49 126 3.6E-10 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CU254_RS31160 8ccdd74ccf2eede637d878c29087d887 194 Gene3D G3DSA:3.40.50.360 1 190 3.2E-37 T 28-03-2018 IPR029039 Flavoprotein-like domain CU254_RS32970 6df56ad6c8192198f208ddd3489551a8 1418 Gene3D G3DSA:1.10.287.850 93 173 3.6E-12 T 28-03-2018 CU254_RS32970 6df56ad6c8192198f208ddd3489551a8 1418 SUPERFAMILY SSF140453 102 164 3.4E-6 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CU254_RS33810 503ac8dfecc772d56721bf096660566d 562 Gene3D G3DSA:2.30.38.10 358 443 1.7E-14 T 28-03-2018 CU254_RS33810 503ac8dfecc772d56721bf096660566d 562 Gene3D G3DSA:3.40.50.980 3 165 5.1E-20 T 28-03-2018 CU254_RS33810 503ac8dfecc772d56721bf096660566d 562 Gene3D G3DSA:3.40.50.980 166 337 2.7E-25 T 28-03-2018 CU254_RS33810 503ac8dfecc772d56721bf096660566d 562 Gene3D G3DSA:3.30.300.30 444 552 5.0E-16 T 28-03-2018 CU254_RS33810 503ac8dfecc772d56721bf096660566d 562 Pfam PF00501 AMP-binding enzyme 26 451 2.3E-59 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS33810 503ac8dfecc772d56721bf096660566d 562 SUPERFAMILY SSF56801 368 557 1.31E-85 T 28-03-2018 CU254_RS33810 503ac8dfecc772d56721bf096660566d 562 SUPERFAMILY SSF56801 9 336 1.31E-85 T 28-03-2018 CU254_RS03255 4eddaf97554d18b964dee5036c3b6ef3 434 Gene3D G3DSA:1.20.1250.20 25 217 5.5E-14 T 28-03-2018 CU254_RS03255 4eddaf97554d18b964dee5036c3b6ef3 434 Pfam PF05977 Transmembrane secretion effector 24 425 2.0E-31 T 28-03-2018 IPR010290 Transmembrane secretion effector CU254_RS03255 4eddaf97554d18b964dee5036c3b6ef3 434 Gene3D G3DSA:1.20.1250.20 228 431 1.6E-17 T 28-03-2018 CU254_RS03255 4eddaf97554d18b964dee5036c3b6ef3 434 SUPERFAMILY SSF103473 36 420 6.02E-34 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS16390 e88a35a164f76900958fef6a8b78897f 402 SUPERFAMILY SSF51338 355 395 1.43E-8 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS16390 e88a35a164f76900958fef6a8b78897f 402 SUPERFAMILY SSF51338 7 48 1.43E-8 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS16390 e88a35a164f76900958fef6a8b78897f 402 Gene3D G3DSA:2.30.40.10 2 56 7.8E-10 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS16390 e88a35a164f76900958fef6a8b78897f 402 Pfam PF07969 Amidohydrolase family 91 388 6.7E-11 T 28-03-2018 IPR013108 Amidohydrolase 3 CU254_RS16390 e88a35a164f76900958fef6a8b78897f 402 Gene3D G3DSA:3.20.20.140 57 332 1.1E-29 T 28-03-2018 CU254_RS16390 e88a35a164f76900958fef6a8b78897f 402 SUPERFAMILY SSF51556 50 364 2.43E-67 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS16390 e88a35a164f76900958fef6a8b78897f 402 Gene3D G3DSA:2.30.40.10 333 395 2.1E-4 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS06050 bca0488dc89eba5063a5f96142791bfa 373 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 47 288 8.8E-70 T 28-03-2018 IPR019079 Capsule synthesis protein, CapA CU254_RS06050 bca0488dc89eba5063a5f96142791bfa 373 ProSitePatterns PS00430 TonB-dependent receptor proteins signature 1. 1 51 - T 28-03-2018 IPR010916 TonB box, conserved site CU254_RS06050 bca0488dc89eba5063a5f96142791bfa 373 SUPERFAMILY SSF56300 47 310 1.19E-36 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CU254_RS06050 bca0488dc89eba5063a5f96142791bfa 373 SMART SM00854 47 291 6.7E-78 T 28-03-2018 IPR019079 Capsule synthesis protein, CapA CU254_RS06050 bca0488dc89eba5063a5f96142791bfa 373 Gene3D G3DSA:3.60.21.10 35 360 1.7E-58 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CU254_RS19160 954752b834f65dba17ca7cfa7361bf06 265 Pfam PF00753 Metallo-beta-lactamase superfamily 17 208 8.1E-18 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS19160 954752b834f65dba17ca7cfa7361bf06 265 SMART SM00849 18 208 9.8E-17 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS19160 954752b834f65dba17ca7cfa7361bf06 265 SUPERFAMILY SSF56281 9 228 7.18E-31 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS19160 954752b834f65dba17ca7cfa7361bf06 265 Gene3D G3DSA:3.60.15.10 2 247 6.3E-28 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS17335 9ad29e90493de1a3bc1e32c296f0387e 147 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 14 141 4.0E-9 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CU254_RS17335 9ad29e90493de1a3bc1e32c296f0387e 147 SUPERFAMILY SSF55961 1 143 2.55E-20 T 28-03-2018 CU254_RS17335 9ad29e90493de1a3bc1e32c296f0387e 147 Gene3D G3DSA:3.30.530.20 1 144 1.7E-17 T 28-03-2018 IPR023393 START-like domain CU254_RS34295 4a42f5077b59c8089be4a91a4f0e48c7 232 Pfam PF14335 Domain of unknown function (DUF4391) 8 216 1.6E-40 T 28-03-2018 IPR025503 Protein of unknown function DUF4391 CU254_RS00920 d88f3006c73d6a5049a3fe32c72a8a76 230 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 47 218 3.5E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS00920 d88f3006c73d6a5049a3fe32c72a8a76 230 SUPERFAMILY SSF161098 28 212 1.83E-30 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS00920 d88f3006c73d6a5049a3fe32c72a8a76 230 Gene3D G3DSA:1.10.3720.10 22 223 7.6E-25 T 28-03-2018 CU254_RS15470 2a5dc14a269e9a79d01cd782c2d74fad 204 Pfam PF01865 Protein of unknown function DUF47 8 201 5.3E-24 T 28-03-2018 IPR018445 Putative phosphate transport regulator CU254_RS15470 2a5dc14a269e9a79d01cd782c2d74fad 204 Gene3D G3DSA:1.20.58.220 119 203 0.027 T 28-03-2018 CU254_RS15560 91706ced442a4b0c21842b2e248e8939 177 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 54 2.4E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS15560 91706ced442a4b0c21842b2e248e8939 177 Gene3D G3DSA:1.10.357.10 57 177 8.1E-13 T 28-03-2018 CU254_RS15560 91706ced442a4b0c21842b2e248e8939 177 Gene3D G3DSA:1.10.260.40 34 56 5.0E-7 T 28-03-2018 CU254_RS15560 91706ced442a4b0c21842b2e248e8939 177 SUPERFAMILY SSF48498 70 175 2.0E-16 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS15560 91706ced442a4b0c21842b2e248e8939 177 ProSitePatterns PS01081 TetR-type HTH domain signature. 20 51 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CU254_RS15560 91706ced442a4b0c21842b2e248e8939 177 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 70 142 3.1E-7 T 28-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 CU254_RS15560 91706ced442a4b0c21842b2e248e8939 177 Gene3D G3DSA:1.10.10.60 1 33 1.1E-12 T 28-03-2018 CU254_RS15560 91706ced442a4b0c21842b2e248e8939 177 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 2.3E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS15560 91706ced442a4b0c21842b2e248e8939 177 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 2.3E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS15560 91706ced442a4b0c21842b2e248e8939 177 SUPERFAMILY SSF46689 2 61 7.48E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS31255 237079bb722f94ee838f953bfda9813e 121 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 2 116 17.052 T 28-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CU254_RS31255 237079bb722f94ee838f953bfda9813e 121 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 4 84 6.0E-24 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CU254_RS31255 237079bb722f94ee838f953bfda9813e 121 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 9 84 5.0E-26 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CU254_RS31255 237079bb722f94ee838f953bfda9813e 121 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 4 102 7.2E-23 T 28-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CU254_RS31255 237079bb722f94ee838f953bfda9813e 121 SUPERFAMILY SSF51344 4 86 8.89E-20 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CU254_RS31255 237079bb722f94ee838f953bfda9813e 121 Gene3D G3DSA:2.60.15.10 1 90 2.5E-25 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CU254_RS31395 987b3f0a9d0c6740ca473595861a48c5 479 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 94 112 - T 28-03-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site CU254_RS31395 987b3f0a9d0c6740ca473595861a48c5 479 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 341 436 6.9E-14 T 28-03-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 CU254_RS31395 987b3f0a9d0c6740ca473595861a48c5 479 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 53 479 38.679 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CU254_RS31395 987b3f0a9d0c6740ca473595861a48c5 479 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 322 341 4.6E-16 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CU254_RS31395 987b3f0a9d0c6740ca473595861a48c5 479 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 114 126 4.6E-16 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CU254_RS31395 987b3f0a9d0c6740ca473595861a48c5 479 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 436 449 4.6E-16 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CU254_RS31395 987b3f0a9d0c6740ca473595861a48c5 479 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 94 112 4.6E-16 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CU254_RS31395 987b3f0a9d0c6740ca473595861a48c5 479 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 229 242 4.6E-16 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CU254_RS31395 987b3f0a9d0c6740ca473595861a48c5 479 SUPERFAMILY SSF51419 64 333 5.09E-73 T 28-03-2018 IPR029066 PLP-binding barrel CU254_RS31395 987b3f0a9d0c6740ca473595861a48c5 479 Gene3D G3DSA:2.40.37.10 318 479 2.3E-38 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CU254_RS31395 987b3f0a9d0c6740ca473595861a48c5 479 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 45 479 1.8E-139 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CU254_RS31395 987b3f0a9d0c6740ca473595861a48c5 479 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 268 285 - T 28-03-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site CU254_RS31395 987b3f0a9d0c6740ca473595861a48c5 479 Gene3D G3DSA:3.20.20.10 72 317 7.2E-65 T 28-03-2018 IPR029066 PLP-binding barrel CU254_RS31395 987b3f0a9d0c6740ca473595861a48c5 479 PRINTS PR01181 Diaminopimelate decarboxylase signature 201 210 7.4E-28 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CU254_RS31395 987b3f0a9d0c6740ca473595861a48c5 479 PRINTS PR01181 Diaminopimelate decarboxylase signature 355 373 7.4E-28 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CU254_RS31395 987b3f0a9d0c6740ca473595861a48c5 479 PRINTS PR01181 Diaminopimelate decarboxylase signature 446 468 7.4E-28 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CU254_RS31395 987b3f0a9d0c6740ca473595861a48c5 479 PRINTS PR01181 Diaminopimelate decarboxylase signature 112 129 7.4E-28 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CU254_RS31395 987b3f0a9d0c6740ca473595861a48c5 479 SUPERFAMILY SSF50621 306 478 5.86E-45 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CU254_RS31395 987b3f0a9d0c6740ca473595861a48c5 479 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 73 331 5.8E-63 T 28-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 CU254_RS27195 fc451ddf92d41bd287ef27c1b59d5421 443 Gene3D G3DSA:3.30.200.20 26 112 5.2E-22 T 28-03-2018 CU254_RS27195 fc451ddf92d41bd287ef27c1b59d5421 443 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 148 160 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CU254_RS27195 fc451ddf92d41bd287ef27c1b59d5421 443 Pfam PF00069 Protein kinase domain 32 274 3.1E-44 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CU254_RS27195 fc451ddf92d41bd287ef27c1b59d5421 443 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 38 61 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 CU254_RS27195 fc451ddf92d41bd287ef27c1b59d5421 443 PIRSF PIRSF000654 28 283 2.7E-21 T 28-03-2018 CU254_RS27195 fc451ddf92d41bd287ef27c1b59d5421 443 SUPERFAMILY SSF56112 28 285 1.62E-71 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS27195 fc451ddf92d41bd287ef27c1b59d5421 443 SUPERFAMILY SSF56112 344 418 1.62E-71 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS27195 fc451ddf92d41bd287ef27c1b59d5421 443 SMART SM00220 32 278 1.8E-56 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CU254_RS27195 fc451ddf92d41bd287ef27c1b59d5421 443 Gene3D G3DSA:1.10.510.10 113 360 2.8E-47 T 28-03-2018 CU254_RS03545 826af50a6ade12d23de0f1ee245b0930 274 SUPERFAMILY SSF53448 1 251 3.44E-43 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS03545 826af50a6ade12d23de0f1ee245b0930 274 Gene3D G3DSA:3.90.550.10 1 260 9.8E-39 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS03545 826af50a6ade12d23de0f1ee245b0930 274 Pfam PF00535 Glycosyl transferase family 2 1 181 5.7E-18 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CU254_RS17260 dc824636ee6898ae16af747847ba5360 216 SUPERFAMILY SSF55718 129 213 5.89E-10 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CU254_RS17260 dc824636ee6898ae16af747847ba5360 216 Gene3D G3DSA:3.30.1050.10 111 215 2.0E-12 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CU254_RS17260 dc824636ee6898ae16af747847ba5360 216 Gene3D G3DSA:1.10.10.10 5 110 3.6E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS17260 dc824636ee6898ae16af747847ba5360 216 Pfam PF01638 HxlR-like helix-turn-helix 19 107 2.4E-19 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type CU254_RS17260 dc824636ee6898ae16af747847ba5360 216 Pfam PF02036 SCP-2 sterol transfer family 130 209 5.7E-6 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CU254_RS17260 dc824636ee6898ae16af747847ba5360 216 SUPERFAMILY SSF46785 7 113 2.62E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS21280 6918331a1d1a36c29ab3be09d4818e62 155 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 6 59 6.0E-6 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CU254_RS21280 6918331a1d1a36c29ab3be09d4818e62 155 Pfam PF01799 [2Fe-2S] binding domain 73 145 2.2E-32 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CU254_RS21280 6918331a1d1a36c29ab3be09d4818e62 155 SUPERFAMILY SSF47741 84 150 1.44E-33 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CU254_RS21280 6918331a1d1a36c29ab3be09d4818e62 155 Gene3D G3DSA:1.10.150.120 75 155 9.4E-37 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CU254_RS21280 6918331a1d1a36c29ab3be09d4818e62 155 Gene3D G3DSA:3.10.20.30 1 74 5.4E-23 T 28-03-2018 IPR012675 Beta-grasp domain CU254_RS21280 6918331a1d1a36c29ab3be09d4818e62 155 SUPERFAMILY SSF54292 3 78 4.19E-23 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CU254_RS28320 4a42117a5fb594ee28a4990556a48d0d 326 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 5 188 1.7E-55 T 28-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CU254_RS28320 4a42117a5fb594ee28a4990556a48d0d 326 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 231 319 1.2E-17 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CU254_RS28320 4a42117a5fb594ee28a4990556a48d0d 326 SUPERFAMILY SSF90002 231 319 1.44E-20 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CU254_RS28320 4a42117a5fb594ee28a4990556a48d0d 326 Gene3D G3DSA:3.30.1220.10 212 321 1.1E-22 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CU254_RS28320 4a42117a5fb594ee28a4990556a48d0d 326 SUPERFAMILY SSF52540 3 212 2.66E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS28320 4a42117a5fb594ee28a4990556a48d0d 326 SMART SM00833 230 320 9.6E-14 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CU254_RS28320 4a42117a5fb594ee28a4990556a48d0d 326 Gene3D G3DSA:3.40.50.300 1 207 1.4E-49 T 28-03-2018 CU254_RS05265 8431e06b32160ea24625bd7d61a1f44a 405 SUPERFAMILY SSF56672 8 235 2.05E-77 T 28-03-2018 CU254_RS05265 8431e06b32160ea24625bd7d61a1f44a 405 Gene3D G3DSA:3.30.70.270 41 114 2.6E-22 T 28-03-2018 CU254_RS05265 8431e06b32160ea24625bd7d61a1f44a 405 Gene3D G3DSA:3.30.70.270 115 170 3.9E-15 T 28-03-2018 CU254_RS05265 8431e06b32160ea24625bd7d61a1f44a 405 Pfam PF00817 impB/mucB/samB family 13 153 1.9E-46 T 28-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CU254_RS05265 8431e06b32160ea24625bd7d61a1f44a 405 Pfam PF11799 impB/mucB/samB family C-terminal domain 235 345 2.7E-17 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CU254_RS05265 8431e06b32160ea24625bd7d61a1f44a 405 Gene3D G3DSA:1.10.150.20 171 243 2.9E-22 T 28-03-2018 CU254_RS05265 8431e06b32160ea24625bd7d61a1f44a 405 SUPERFAMILY SSF100879 240 342 4.51E-19 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CU254_RS05265 8431e06b32160ea24625bd7d61a1f44a 405 Hamap MF_01113 DNA polymerase IV [dinB]. 6 353 33.813 T 28-03-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 CU254_RS05265 8431e06b32160ea24625bd7d61a1f44a 405 Pfam PF11798 IMS family HHH motif 166 197 2.7E-7 T 28-03-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 CU254_RS05265 8431e06b32160ea24625bd7d61a1f44a 405 Gene3D G3DSA:3.30.1490.100 244 355 5.4E-25 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CU254_RS03330 c15829d6afc2a8401a5299c6cfc2d3cb 392 Gene3D G3DSA:3.90.1720.10 272 387 4.0E-28 T 28-03-2018 CU254_RS03330 c15829d6afc2a8401a5299c6cfc2d3cb 392 Pfam PF00877 NlpC/P60 family 282 376 1.1E-21 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CU254_RS03330 c15829d6afc2a8401a5299c6cfc2d3cb 392 SUPERFAMILY SSF54001 273 386 5.89E-32 T 28-03-2018 CU254_RS03330 c15829d6afc2a8401a5299c6cfc2d3cb 392 Gene3D G3DSA:1.10.530.10 117 271 5.8E-4 T 28-03-2018 CU254_RS15340 edb3e4a15bd8f053775794798ede429c 264 SMART SM00346 8 99 4.9E-7 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS15340 edb3e4a15bd8f053775794798ede429c 264 Pfam PF09339 IclR helix-turn-helix domain 12 62 3.0E-7 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS15340 edb3e4a15bd8f053775794798ede429c 264 SUPERFAMILY SSF46785 12 82 7.63E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS15340 edb3e4a15bd8f053775794798ede429c 264 Gene3D G3DSA:3.30.450.40 83 264 3.6E-36 T 28-03-2018 IPR029016 GAF domain-like CU254_RS15340 edb3e4a15bd8f053775794798ede429c 264 Pfam PF01614 Bacterial transcriptional regulator 140 257 5.9E-14 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal CU254_RS15340 edb3e4a15bd8f053775794798ede429c 264 SUPERFAMILY SSF55781 68 261 1.18E-31 T 28-03-2018 IPR029016 GAF domain-like CU254_RS15340 edb3e4a15bd8f053775794798ede429c 264 Gene3D G3DSA:1.10.10.10 2 71 1.8E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS00100 b2f52ebf4f5faec54c0d95813885b3df 287 SUPERFAMILY SSF56601 76 270 1.32E-20 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CU254_RS00100 b2f52ebf4f5faec54c0d95813885b3df 287 Gene3D G3DSA:3.40.710.10 74 283 5.0E-21 T 28-03-2018 CU254_RS37720 e575173bec2a20518c3a48ade5feb5ec 211 Gene3D G3DSA:3.60.15.10 3 208 1.3E-26 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS37720 e575173bec2a20518c3a48ade5feb5ec 211 SUPERFAMILY SSF56281 1 196 3.67E-26 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS37720 e575173bec2a20518c3a48ade5feb5ec 211 SMART SM00849 7 176 4.7E-9 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS37720 e575173bec2a20518c3a48ade5feb5ec 211 Pfam PF13483 Beta-lactamase superfamily domain 3 176 8.3E-21 T 28-03-2018 CU254_RS29295 c112f36ced2e281ff1f7e6e05241904d 482 Gene3D G3DSA:3.40.605.10 6 270 1.7E-73 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CU254_RS29295 c112f36ced2e281ff1f7e6e05241904d 482 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 252 259 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CU254_RS29295 c112f36ced2e281ff1f7e6e05241904d 482 Gene3D G3DSA:3.40.309.10 271 459 3.5E-69 T 28-03-2018 CU254_RS29295 c112f36ced2e281ff1f7e6e05241904d 482 SUPERFAMILY SSF53720 11 477 1.15E-143 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CU254_RS29295 c112f36ced2e281ff1f7e6e05241904d 482 Pfam PF00171 Aldehyde dehydrogenase family 18 475 4.1E-151 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CU254_RS29295 c112f36ced2e281ff1f7e6e05241904d 482 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 280 291 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CU254_RS37590 113f4dfc14fa4cba6697c955d025206a 356 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 8 337 1.2E-132 T 28-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CU254_RS37590 113f4dfc14fa4cba6697c955d025206a 356 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 7 349 41.032 T 28-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CU254_RS37590 113f4dfc14fa4cba6697c955d025206a 356 Gene3D G3DSA:3.30.1330.10 37 162 1.4E-46 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CU254_RS37590 113f4dfc14fa4cba6697c955d025206a 356 Gene3D G3DSA:3.90.650.10 172 344 2.1E-51 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CU254_RS37590 113f4dfc14fa4cba6697c955d025206a 356 Pfam PF00586 AIR synthase related protein, N-terminal domain 62 165 1.1E-14 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CU254_RS37590 113f4dfc14fa4cba6697c955d025206a 356 SUPERFAMILY SSF56042 173 340 1.18E-50 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CU254_RS37590 113f4dfc14fa4cba6697c955d025206a 356 SUPERFAMILY SSF55326 7 169 1.4E-42 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CU254_RS37590 113f4dfc14fa4cba6697c955d025206a 356 Pfam PF02769 AIR synthase related protein, C-terminal domain 177 341 2.2E-28 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CU254_RS34270 ae3ee5b10352fd52b0bca48c98056f66 194 Gene3D G3DSA:1.10.10.60 2 58 4.4E-13 T 28-03-2018 CU254_RS34270 ae3ee5b10352fd52b0bca48c98056f66 194 Gene3D G3DSA:1.10.357.10 61 194 2.1E-11 T 28-03-2018 CU254_RS34270 ae3ee5b10352fd52b0bca48c98056f66 194 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 82 194 1.1E-11 T 28-03-2018 CU254_RS34270 ae3ee5b10352fd52b0bca48c98056f66 194 SUPERFAMILY SSF48498 81 193 2.07E-14 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS34270 ae3ee5b10352fd52b0bca48c98056f66 194 SUPERFAMILY SSF46689 3 86 1.39E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS34270 ae3ee5b10352fd52b0bca48c98056f66 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 57 4.2E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS19005 eb7fe9e67a4acb3f961ec473418d282a 332 Pfam PF08279 HTH domain 7 62 2.1E-16 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 CU254_RS19005 eb7fe9e67a4acb3f961ec473418d282a 332 SUPERFAMILY SSF46785 5 63 4.58E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS19005 eb7fe9e67a4acb3f961ec473418d282a 332 ProSitePatterns PS00894 DeoR-type HTH domain signature. 7 41 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CU254_RS19005 eb7fe9e67a4acb3f961ec473418d282a 332 Gene3D G3DSA:1.10.10.10 1 66 1.3E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS19005 eb7fe9e67a4acb3f961ec473418d282a 332 Pfam PF13280 WYL domain 136 302 7.1E-27 T 28-03-2018 IPR026881 WYL domain CU254_RS19005 eb7fe9e67a4acb3f961ec473418d282a 332 PIRSF PIRSF016838 2 314 6.4E-19 T 28-03-2018 IPR028349 Protein PafC CU254_RS38215 45b4208b391dbf9afad27772c413ad87 184 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 23 178 1.6E-30 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS38215 45b4208b391dbf9afad27772c413ad87 184 Gene3D G3DSA:1.10.10.10 97 183 1.3E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS38215 45b4208b391dbf9afad27772c413ad87 184 Pfam PF04542 Sigma-70 region 2 28 94 4.0E-16 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS38215 45b4208b391dbf9afad27772c413ad87 184 SUPERFAMILY SSF88946 7 107 1.57E-28 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS38215 45b4208b391dbf9afad27772c413ad87 184 Gene3D G3DSA:1.10.1740.10 5 96 2.9E-25 T 28-03-2018 CU254_RS38215 45b4208b391dbf9afad27772c413ad87 184 Pfam PF08281 Sigma-70, region 4 124 176 5.6E-14 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS38215 45b4208b391dbf9afad27772c413ad87 184 SUPERFAMILY SSF88659 122 181 1.68E-13 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS10585 a23d9bfc72cb881c82652fa2ade46bb1 262 SUPERFAMILY SSF52096 5 261 3.17E-79 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS10585 a23d9bfc72cb881c82652fa2ade46bb1 262 Gene3D G3DSA:3.90.226.10 1 209 1.4E-63 T 28-03-2018 CU254_RS10585 a23d9bfc72cb881c82652fa2ade46bb1 262 Gene3D G3DSA:1.10.12.10 210 262 2.8E-17 T 28-03-2018 IPR014748 Crontonase, C-terminal CU254_RS10585 a23d9bfc72cb881c82652fa2ade46bb1 262 Pfam PF00378 Enoyl-CoA hydratase/isomerase 15 261 3.3E-58 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CU254_RS05960 e204e3237e52730076e8bae6fb6317cc 199 Pfam PF00174 Oxidoreductase molybdopterin binding domain 35 179 1.3E-30 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CU254_RS05960 e204e3237e52730076e8bae6fb6317cc 199 Gene3D G3DSA:3.90.420.10 21 199 2.1E-47 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CU254_RS05960 e204e3237e52730076e8bae6fb6317cc 199 SUPERFAMILY SSF56524 18 197 3.4E-54 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CU254_RS31810 1f6e4ecf0023521c5582825d8b74022f 442 ProSitePatterns PS00455 Putative AMP-binding domain signature. 125 136 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS31810 1f6e4ecf0023521c5582825d8b74022f 442 SUPERFAMILY SSF56801 15 441 7.2E-91 T 28-03-2018 CU254_RS31810 1f6e4ecf0023521c5582825d8b74022f 442 Gene3D G3DSA:3.40.50.980 131 273 1.5E-32 T 28-03-2018 CU254_RS31810 1f6e4ecf0023521c5582825d8b74022f 442 Gene3D G3DSA:3.40.50.980 108 130 0.29 T 28-03-2018 CU254_RS31810 1f6e4ecf0023521c5582825d8b74022f 442 Pfam PF00501 AMP-binding enzyme 113 351 2.0E-47 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS31810 1f6e4ecf0023521c5582825d8b74022f 442 Pfam PF00501 AMP-binding enzyme 17 100 3.2E-5 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS31810 1f6e4ecf0023521c5582825d8b74022f 442 Gene3D G3DSA:3.30.300.30 344 442 2.2E-17 T 28-03-2018 CU254_RS31810 1f6e4ecf0023521c5582825d8b74022f 442 Gene3D G3DSA:3.40.50.980 5 107 9.3E-6 T 28-03-2018 CU254_RS31810 1f6e4ecf0023521c5582825d8b74022f 442 Gene3D G3DSA:2.30.38.10 274 343 3.7E-14 T 28-03-2018 CU254_RS31810 1f6e4ecf0023521c5582825d8b74022f 442 Pfam PF13193 AMP-binding enzyme C-terminal domain 363 434 6.8E-12 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS25305 38baab17bc8e34e15729c0320fe275b1 175 Pfam PF07883 Cupin domain 103 162 1.9E-16 T 28-03-2018 IPR013096 Cupin 2, conserved barrel CU254_RS25305 38baab17bc8e34e15729c0320fe275b1 175 Gene3D G3DSA:1.10.260.40 1 59 2.0E-10 T 28-03-2018 CU254_RS25305 38baab17bc8e34e15729c0320fe275b1 175 SUPERFAMILY SSF47413 1 49 9.57E-10 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS25305 38baab17bc8e34e15729c0320fe275b1 175 SUPERFAMILY SSF51182 55 166 5.49E-22 T 28-03-2018 IPR011051 RmlC-like cupin domain CU254_RS25305 38baab17bc8e34e15729c0320fe275b1 175 Gene3D G3DSA:2.60.120.10 60 169 4.5E-19 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS25305 38baab17bc8e34e15729c0320fe275b1 175 Pfam PF01381 Helix-turn-helix 1 46 2.1E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS02445 c73b9459a51123b3ae6bc90e1171dc32 568 SUPERFAMILY SSF51905 11 308 1.81E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS02445 c73b9459a51123b3ae6bc90e1171dc32 568 SUPERFAMILY SSF51905 470 529 1.81E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS02445 c73b9459a51123b3ae6bc90e1171dc32 568 Pfam PF05199 GMC oxidoreductase 468 525 5.3E-14 T 28-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 CU254_RS02445 c73b9459a51123b3ae6bc90e1171dc32 568 Pfam PF00732 GMC oxidoreductase 15 283 3.2E-13 T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CU254_RS02445 c73b9459a51123b3ae6bc90e1171dc32 568 Gene3D G3DSA:3.50.50.60 1 550 3.3E-65 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS40055 4be07fa5c5b8fb9f96000b6d8d7815bf 335 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 2 215 8.6E-71 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CU254_RS40055 4be07fa5c5b8fb9f96000b6d8d7815bf 335 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 3 320 1.1E-102 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CU254_RS40055 4be07fa5c5b8fb9f96000b6d8d7815bf 335 PIRSF PIRSF000267 1 333 1.4E-109 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CU254_RS32015 0475fcb798b479f26c0120802b94965c 461 SUPERFAMILY SSF55103 219 457 1.19E-48 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CU254_RS32015 0475fcb798b479f26c0120802b94965c 461 Pfam PF01565 FAD binding domain 40 178 3.8E-39 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CU254_RS32015 0475fcb798b479f26c0120802b94965c 461 Gene3D G3DSA:3.30.465.10 93 236 6.3E-39 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CU254_RS32015 0475fcb798b479f26c0120802b94965c 461 Gene3D G3DSA:1.10.45.10 416 455 4.4E-10 T 28-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CU254_RS32015 0475fcb798b479f26c0120802b94965c 461 Gene3D G3DSA:3.30.43.10 1 92 2.2E-20 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CU254_RS32015 0475fcb798b479f26c0120802b94965c 461 SUPERFAMILY SSF56176 2 213 1.45E-62 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CU254_RS32015 0475fcb798b479f26c0120802b94965c 461 Pfam PF02913 FAD linked oxidases, C-terminal domain 218 453 3.0E-51 T 28-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CU254_RS18160 82e2fb7dd1eb00f637159455990d69e4 311 SUPERFAMILY SSF52540 1 261 2.77E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS18160 82e2fb7dd1eb00f637159455990d69e4 311 Gene3D G3DSA:3.40.50.300 1 268 1.7E-48 T 28-03-2018 CU254_RS18160 82e2fb7dd1eb00f637159455990d69e4 311 Pfam PF13614 AAA domain 1 179 2.1E-32 T 28-03-2018 IPR025669 AAA domain CU254_RS42665 443bb199f61a3150a5f04bc10ad12c08 1060 Gene3D G3DSA:3.40.1360.10 757 877 2.4E-15 T 28-03-2018 CU254_RS42665 443bb199f61a3150a5f04bc10ad12c08 1060 SUPERFAMILY SSF56731 633 890 1.57E-47 T 28-03-2018 CU254_RS42665 443bb199f61a3150a5f04bc10ad12c08 1060 Pfam PF13155 Toprim-like 776 857 3.6E-9 T 28-03-2018 CU254_RS42665 443bb199f61a3150a5f04bc10ad12c08 1060 Pfam PF08275 DNA primase catalytic core, N-terminal domain 651 767 4.5E-24 T 28-03-2018 IPR013264 DNA primase, catalytic core, N-terminal CU254_RS42665 443bb199f61a3150a5f04bc10ad12c08 1060 Gene3D G3DSA:3.90.980.10 625 756 4.1E-30 T 28-03-2018 IPR013264 DNA primase, catalytic core, N-terminal CU254_RS38810 3fb9a55d915ad6349db0710ef5a24a09 235 Pfam PF02390 Putative methyltransferase 59 228 4.1E-54 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CU254_RS38810 3fb9a55d915ad6349db0710ef5a24a09 235 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 16 235 29.769 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CU254_RS38810 3fb9a55d915ad6349db0710ef5a24a09 235 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 49 234 4.8E-49 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CU254_RS38810 3fb9a55d915ad6349db0710ef5a24a09 235 Gene3D G3DSA:3.40.50.150 22 235 7.1E-32 T 28-03-2018 CU254_RS38810 3fb9a55d915ad6349db0710ef5a24a09 235 SUPERFAMILY SSF53335 10 234 4.67E-33 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS12840 6c1bd350c37224899eb3e30dd2620965 420 Gene3D G3DSA:1.20.1090.10 202 393 1.0E-41 T 28-03-2018 CU254_RS12840 6c1bd350c37224899eb3e30dd2620965 420 SUPERFAMILY SSF56796 35 387 2.21E-76 T 28-03-2018 CU254_RS12840 6c1bd350c37224899eb3e30dd2620965 420 Gene3D G3DSA:3.40.50.1970 27 201 3.0E-39 T 28-03-2018 CU254_RS12840 6c1bd350c37224899eb3e30dd2620965 420 Pfam PF01761 3-dehydroquinate synthase 96 350 6.5E-65 T 28-03-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CU254_RS05640 6ab43cf599691193b641c8882c61c956 173 SUPERFAMILY SSF47598 106 154 2.95E-12 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 CU254_RS05640 6ab43cf599691193b641c8882c61c956 173 Pfam PF05534 HicB family 109 141 7.6E-6 T 28-03-2018 IPR008651 Uncharacterised protein family HicB CU254_RS05640 6ab43cf599691193b641c8882c61c956 173 Gene3D G3DSA:1.10.1220.10 108 148 5.8E-15 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CU254_RS26735 98b124bfa80d38b2fa06524367e60285 97 Gene3D G3DSA:3.40.630.30 49 93 0.0049 T 28-03-2018 CU254_RS41185 ae7ef4b1faacf629c8639ff913344a2f 146 SMART SM00357 84 145 1.6E-5 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 CU254_RS41185 ae7ef4b1faacf629c8639ff913344a2f 146 SUPERFAMILY SSF50249 83 136 3.21E-10 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CU254_RS41185 ae7ef4b1faacf629c8639ff913344a2f 146 Pfam PF00313 'Cold-shock' DNA-binding domain 84 131 2.0E-7 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CU254_RS41185 ae7ef4b1faacf629c8639ff913344a2f 146 Gene3D G3DSA:2.40.50.140 60 146 1.4E-10 T 28-03-2018 CU254_RS33305 92fdf03fb8755ea4a960ee5b2fc6f358 246 SUPERFAMILY SSF46785 5 73 3.37E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS33305 92fdf03fb8755ea4a960ee5b2fc6f358 246 Pfam PF01614 Bacterial transcriptional regulator 122 240 6.1E-32 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal CU254_RS33305 92fdf03fb8755ea4a960ee5b2fc6f358 246 Pfam PF09339 IclR helix-turn-helix domain 5 55 3.6E-15 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS33305 92fdf03fb8755ea4a960ee5b2fc6f358 246 SMART SM00346 2 92 4.8E-20 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS33305 92fdf03fb8755ea4a960ee5b2fc6f358 246 Gene3D G3DSA:3.30.450.40 76 245 2.1E-50 T 28-03-2018 IPR029016 GAF domain-like CU254_RS33305 92fdf03fb8755ea4a960ee5b2fc6f358 246 Gene3D G3DSA:1.10.10.10 2 75 2.3E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS33305 92fdf03fb8755ea4a960ee5b2fc6f358 246 SUPERFAMILY SSF55781 67 244 2.35E-49 T 28-03-2018 IPR029016 GAF domain-like CU254_RS21455 dbbb212094ea511e1429714dae69c3ab 172 SUPERFAMILY SSF53271 9 164 3.83E-38 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CU254_RS21455 dbbb212094ea511e1429714dae69c3ab 172 Pfam PF00156 Phosphoribosyl transferase domain 35 150 9.3E-8 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CU254_RS21455 dbbb212094ea511e1429714dae69c3ab 172 Gene3D G3DSA:3.40.50.2020 1 170 7.8E-32 T 28-03-2018 CU254_RS21455 dbbb212094ea511e1429714dae69c3ab 172 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 6 172 30.715 T 28-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 CU254_RS20380 4aa13b6d7eee0b95337a6c1a08ed45cf 300 Gene3D G3DSA:3.40.50.720 1 141 3.7E-14 T 28-03-2018 CU254_RS20380 4aa13b6d7eee0b95337a6c1a08ed45cf 300 SUPERFAMILY SSF51735 4 152 1.78E-22 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS20380 4aa13b6d7eee0b95337a6c1a08ed45cf 300 Pfam PF09290 Prokaryotic acetaldehyde dehydrogenase, dimerisation 128 273 2.2E-65 T 28-03-2018 IPR015426 Acetaldehyde dehydrogenase, C-terminal GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 CU254_RS20380 4aa13b6d7eee0b95337a6c1a08ed45cf 300 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 8 114 4.2E-10 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CU254_RS20380 4aa13b6d7eee0b95337a6c1a08ed45cf 300 TIGRFAM TIGR03215 ac_ald_DH_ac: acetaldehyde dehydrogenase (acetylating) 5 298 2.2E-135 T 28-03-2018 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 CU254_RS20380 4aa13b6d7eee0b95337a6c1a08ed45cf 300 Gene3D G3DSA:3.30.360.10 142 273 2.3E-69 T 28-03-2018 CU254_RS20380 4aa13b6d7eee0b95337a6c1a08ed45cf 300 SMART SM00859 7 120 2.4E-5 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CU254_RS20380 4aa13b6d7eee0b95337a6c1a08ed45cf 300 PIRSF PIRSF015689 2 300 2.0E-132 T 28-03-2018 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 CU254_RS20380 4aa13b6d7eee0b95337a6c1a08ed45cf 300 SUPERFAMILY SSF55347 128 274 2.55E-62 T 28-03-2018 CU254_RS20380 4aa13b6d7eee0b95337a6c1a08ed45cf 300 Hamap MF_01657 Acetaldehyde dehydrogenase [mhpF]. 1 300 131.526 T 28-03-2018 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 CU254_RS38840 bbb2896501eeccbb305c6025cb554b71 225 Gene3D G3DSA:3.40.50.720 173 219 0.29 T 28-03-2018 CU254_RS38840 bbb2896501eeccbb305c6025cb554b71 225 Pfam PF00106 short chain dehydrogenase 7 185 4.8E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS38840 bbb2896501eeccbb305c6025cb554b71 225 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 123 131 5.1E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS38840 bbb2896501eeccbb305c6025cb554b71 225 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 162 5.1E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS38840 bbb2896501eeccbb305c6025cb554b71 225 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 71 82 5.1E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS38840 bbb2896501eeccbb305c6025cb554b71 225 SUPERFAMILY SSF51735 7 212 2.17E-50 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS38840 bbb2896501eeccbb305c6025cb554b71 225 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 162 5.8E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS38840 bbb2896501eeccbb305c6025cb554b71 225 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 5.8E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS38840 bbb2896501eeccbb305c6025cb554b71 225 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 71 82 5.8E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS38840 bbb2896501eeccbb305c6025cb554b71 225 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 117 133 5.8E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS38840 bbb2896501eeccbb305c6025cb554b71 225 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 179 5.8E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS38840 bbb2896501eeccbb305c6025cb554b71 225 Gene3D G3DSA:3.40.50.720 3 172 1.5E-48 T 28-03-2018 CU254_RS38840 bbb2896501eeccbb305c6025cb554b71 225 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 130 158 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS19410 6524b31ffe4ba9748144d342109a3673 189 Gene3D G3DSA:1.10.357.10 68 189 4.1E-14 T 28-03-2018 CU254_RS19410 6524b31ffe4ba9748144d342109a3673 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 63 4.1E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS19410 6524b31ffe4ba9748144d342109a3673 189 Gene3D G3DSA:1.10.260.40 40 67 2.2E-11 T 28-03-2018 CU254_RS19410 6524b31ffe4ba9748144d342109a3673 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 2.5E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS19410 6524b31ffe4ba9748144d342109a3673 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 2.5E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS19410 6524b31ffe4ba9748144d342109a3673 189 SUPERFAMILY SSF46689 6 81 1.25E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS19410 6524b31ffe4ba9748144d342109a3673 189 Gene3D G3DSA:1.10.10.60 2 39 8.0E-12 T 28-03-2018 CU254_RS19410 6524b31ffe4ba9748144d342109a3673 189 SUPERFAMILY SSF48498 84 189 1.2E-10 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS04245 5ad959b164342eddef07cfe262fc8a0c 276 Pfam PF02104 SURF1 family 22 227 5.9E-23 T 28-03-2018 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CU254_RS19105 ee65824eb3819f4e4c00e576c3040ecd 249 Gene3D G3DSA:1.10.357.10 85 249 1.3E-36 T 28-03-2018 CU254_RS19105 ee65824eb3819f4e4c00e576c3040ecd 249 Pfam PF00440 Bacterial regulatory proteins, tetR family 37 80 7.0E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS19105 ee65824eb3819f4e4c00e576c3040ecd 249 SUPERFAMILY SSF46689 24 93 2.14E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS19105 ee65824eb3819f4e4c00e576c3040ecd 249 SUPERFAMILY SSF48498 96 246 1.33E-23 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS19105 ee65824eb3819f4e4c00e576c3040ecd 249 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 93 245 3.5E-18 T 28-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 CU254_RS19105 ee65824eb3819f4e4c00e576c3040ecd 249 Gene3D G3DSA:1.10.10.60 1 84 5.1E-17 T 28-03-2018 CU254_RS01435 89753fc5ad1817d716e4d335f53321cb 354 SUPERFAMILY SSF52518 25 250 7.15E-79 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS01435 89753fc5ad1817d716e4d335f53321cb 354 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 70 217 7.2E-30 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CU254_RS01435 89753fc5ad1817d716e4d335f53321cb 354 Gene3D G3DSA:3.40.50.970 15 98 8.8E-21 T 28-03-2018 CU254_RS01435 89753fc5ad1817d716e4d335f53321cb 354 Gene3D G3DSA:3.40.50.970 99 346 3.1E-40 T 28-03-2018 CU254_RS31280 2f95c3f7e955c641d7f49767e1bec012 184 Pfam PF00430 ATP synthase B/B' CF(0) 24 152 9.5E-28 T 28-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CU254_RS31280 2f95c3f7e955c641d7f49767e1bec012 184 Gene3D G3DSA:1.20.5.620 78 138 2.6E-11 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain CU254_RS31280 2f95c3f7e955c641d7f49767e1bec012 184 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 27 173 2.9E-28 T 28-03-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 CU254_RS31280 2f95c3f7e955c641d7f49767e1bec012 184 Hamap MF_01398 ATP synthase subunit b [atpF]. 10 154 13.488 T 28-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CU254_RS31280 2f95c3f7e955c641d7f49767e1bec012 184 SUPERFAMILY SSF81573 79 137 3.27E-11 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain CU254_RS19495 e6b1390bd05ba62495a76d98b65dc8c7 306 Gene3D G3DSA:1.10.3720.10 16 291 3.3E-40 T 28-03-2018 CU254_RS19495 e6b1390bd05ba62495a76d98b65dc8c7 306 SUPERFAMILY SSF161098 96 284 3.66E-27 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS19495 e6b1390bd05ba62495a76d98b65dc8c7 306 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 26 63 1.3E-5 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CU254_RS19495 e6b1390bd05ba62495a76d98b65dc8c7 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 302 9.9E-25 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS16525 899b638d88b1a9a3075a40c810f724a0 153 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 11 130 1.8E-18 T 28-03-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 CU254_RS16525 899b638d88b1a9a3075a40c810f724a0 153 SUPERFAMILY SSF55961 1 144 9.24E-26 T 28-03-2018 CU254_RS16525 899b638d88b1a9a3075a40c810f724a0 153 Gene3D G3DSA:3.30.530.20 1 147 2.0E-21 T 28-03-2018 IPR023393 START-like domain CU254_RS36555 99e7528199e413a290570045379b4d22 590 SUPERFAMILY SSF51445 24 421 2.32E-101 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS36555 99e7528199e413a290570045379b4d22 590 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 42 384 9.9E-104 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CU254_RS36555 99e7528199e413a290570045379b4d22 590 SUPERFAMILY SSF52279 425 590 3.66E-17 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CU254_RS36555 99e7528199e413a290570045379b4d22 590 Gene3D G3DSA:3.40.50.1700 408 577 1.4E-18 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CU254_RS36555 99e7528199e413a290570045379b4d22 590 Gene3D G3DSA:3.20.20.300 24 407 1.5E-100 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CU254_RS36555 99e7528199e413a290570045379b4d22 590 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 426 590 2.8E-13 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CU254_RS06405 936f7a3a4ec6f7fb21e69f9590e4fecd 251 SMART SM00850 143 239 1.2E-26 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CU254_RS06405 936f7a3a4ec6f7fb21e69f9590e4fecd 251 Gene3D G3DSA:2.40.50.40 138 202 1.6E-13 T 28-03-2018 CU254_RS06405 936f7a3a4ec6f7fb21e69f9590e4fecd 251 Pfam PF04397 LytTr DNA-binding domain 144 238 1.8E-18 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CU254_RS06405 936f7a3a4ec6f7fb21e69f9590e4fecd 251 Gene3D G3DSA:3.40.50.2300 1 137 6.2E-28 T 28-03-2018 CU254_RS06405 936f7a3a4ec6f7fb21e69f9590e4fecd 251 SUPERFAMILY SSF52172 2 121 6.26E-30 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS06405 936f7a3a4ec6f7fb21e69f9590e4fecd 251 Pfam PF00072 Response regulator receiver domain 6 115 3.5E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS06405 936f7a3a4ec6f7fb21e69f9590e4fecd 251 SMART SM00448 4 115 4.1E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS18200 f83e26e80d92ff92c9d4aec1cadbdd50 301 SUPERFAMILY SSF103481 191 285 3.79E-10 T 28-03-2018 CU254_RS18200 f83e26e80d92ff92c9d4aec1cadbdd50 301 SUPERFAMILY SSF103481 39 138 1.24E-12 T 28-03-2018 CU254_RS18200 f83e26e80d92ff92c9d4aec1cadbdd50 301 Pfam PF00892 EamA-like transporter family 10 137 7.3E-19 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CU254_RS18200 f83e26e80d92ff92c9d4aec1cadbdd50 301 Pfam PF00892 EamA-like transporter family 153 284 4.8E-19 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CU254_RS14570 f36d40b8a9e0f3edde1bc7994fb1b3e2 268 Gene3D G3DSA:2.60.120.10 105 254 4.8E-70 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS14570 f36d40b8a9e0f3edde1bc7994fb1b3e2 268 SUPERFAMILY SSF51182 5 238 2.39E-58 T 28-03-2018 IPR011051 RmlC-like cupin domain CU254_RS14570 f36d40b8a9e0f3edde1bc7994fb1b3e2 268 TIGRFAM TIGR04378 myo_inos_iolB: 5-deoxy-glucuronate isomerase 7 250 7.3E-91 T 28-03-2018 IPR024203 5-deoxy-glucuronate isomerase, IolB GO:0008880|GO:0019310 KEGG: 00562+5.3.1.30 CU254_RS14570 f36d40b8a9e0f3edde1bc7994fb1b3e2 268 PIRSF PIRSF036628 2 255 1.2E-88 T 28-03-2018 IPR024203 5-deoxy-glucuronate isomerase, IolB GO:0008880|GO:0019310 KEGG: 00562+5.3.1.30 CU254_RS14570 f36d40b8a9e0f3edde1bc7994fb1b3e2 268 Gene3D G3DSA:2.60.120.10 5 104 2.6E-30 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS14570 f36d40b8a9e0f3edde1bc7994fb1b3e2 268 Pfam PF04962 KduI/IolB family 5 249 2.7E-85 T 28-03-2018 IPR021120 KduI/IolB isomerase GO:0016861 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 CU254_RS38940 f3d820c0cd6f7317e9d7b1aa5b3ac0c7 107 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 2 96 20.68 T 28-03-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 CU254_RS38940 f3d820c0cd6f7317e9d7b1aa5b3ac0c7 107 TIGRFAM TIGR00166 S6: ribosomal protein bS6 3 95 1.9E-24 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS38940 f3d820c0cd6f7317e9d7b1aa5b3ac0c7 107 Gene3D G3DSA:3.30.70.60 3 102 8.2E-28 T 28-03-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 CU254_RS38940 f3d820c0cd6f7317e9d7b1aa5b3ac0c7 107 Pfam PF01250 Ribosomal protein S6 4 93 5.7E-27 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS38940 f3d820c0cd6f7317e9d7b1aa5b3ac0c7 107 SUPERFAMILY SSF54995 2 95 3.01E-30 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS38940 f3d820c0cd6f7317e9d7b1aa5b3ac0c7 107 ProSitePatterns PS01048 Ribosomal protein S6 signature. 45 54 - T 28-03-2018 IPR020815 Ribosomal protein S6, conserved site GO:0003735|GO:0005840|GO:0006412|GO:0019843 CU254_RS23935 0ab6f3448c203f9039a3f9c99fc14c1d 317 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 90 2.4E-9 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS23935 0ab6f3448c203f9039a3f9c99fc14c1d 317 Gene3D G3DSA:1.20.140.10 158 317 2.7E-25 T 28-03-2018 CU254_RS23935 0ab6f3448c203f9039a3f9c99fc14c1d 317 Gene3D G3DSA:1.10.540.10 1 111 8.4E-17 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS23935 0ab6f3448c203f9039a3f9c99fc14c1d 317 SUPERFAMILY SSF56645 1 118 3.1E-14 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS23935 0ab6f3448c203f9039a3f9c99fc14c1d 317 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 179 311 1.3E-17 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS23935 0ab6f3448c203f9039a3f9c99fc14c1d 317 SUPERFAMILY SSF47203 179 314 2.58E-26 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS34020 6ae4b0466c22ed4d80637d4ce6120511 382 Gene3D G3DSA:3.50.50.60 2 373 6.6E-29 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS34020 6ae4b0466c22ed4d80637d4ce6120511 382 Pfam PF01494 FAD binding domain 6 313 5.1E-10 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CU254_RS34020 6ae4b0466c22ed4d80637d4ce6120511 382 SUPERFAMILY SSF51905 265 371 1.11E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS34020 6ae4b0466c22ed4d80637d4ce6120511 382 SUPERFAMILY SSF51905 5 165 1.11E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS34020 6ae4b0466c22ed4d80637d4ce6120511 382 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 293 309 8.4E-11 T 28-03-2018 CU254_RS34020 6ae4b0466c22ed4d80637d4ce6120511 382 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 8.4E-11 T 28-03-2018 CU254_RS34020 6ae4b0466c22ed4d80637d4ce6120511 382 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 278 293 8.4E-11 T 28-03-2018 CU254_RS34020 6ae4b0466c22ed4d80637d4ce6120511 382 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 144 159 8.4E-11 T 28-03-2018 CU254_RS29845 f01705bece97af64dc8e1ddd4366acd4 124 Gene3D G3DSA:1.10.10.60 61 122 0.001 T 28-03-2018 CU254_RS29845 f01705bece97af64dc8e1ddd4366acd4 124 Gene3D G3DSA:1.10.260.40 37 60 0.016 T 28-03-2018 CU254_RS29845 f01705bece97af64dc8e1ddd4366acd4 124 Gene3D G3DSA:1.10.10.60 5 36 0.0074 T 28-03-2018 CU254_RS38985 90aeb514258052e0713b7da09760e102 121 SMART SM00418 32 112 6.1E-4 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS38985 90aeb514258052e0713b7da09760e102 121 Gene3D G3DSA:1.10.10.10 20 76 6.7E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS38985 90aeb514258052e0713b7da09760e102 121 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 34 49 2.3E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS38985 90aeb514258052e0713b7da09760e102 121 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 68 83 2.3E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS38985 90aeb514258052e0713b7da09760e102 121 SUPERFAMILY SSF46785 22 115 8.51E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS38985 90aeb514258052e0713b7da09760e102 121 Gene3D G3DSA:1.10.10.10 77 117 0.0033 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS26510 61b298a755b31d5634bc6ecc843daf2e 123 SUPERFAMILY SSF55399 32 123 5.23E-24 T 28-03-2018 IPR023549 Subtilisin inhibitor GO:0004867 CU254_RS26510 61b298a755b31d5634bc6ecc843daf2e 123 ProDom PD004028 INHIBITOR PROTEASE SERINE DIRECT SEQUENCING SUBTILISIN PRECURSOR SIGNAL INHIBITOR-LIKE INHIBITOR 42 111 8.0E-13 T 28-03-2018 IPR023549 Subtilisin inhibitor GO:0004867 CU254_RS26510 61b298a755b31d5634bc6ecc843daf2e 123 Gene3D G3DSA:3.30.350.10 25 123 1.3E-27 T 28-03-2018 IPR023549 Subtilisin inhibitor GO:0004867 CU254_RS26510 61b298a755b31d5634bc6ecc843daf2e 123 Pfam PF00720 Subtilisin inhibitor-like 27 109 2.8E-24 T 28-03-2018 IPR023549 Subtilisin inhibitor GO:0004867 CU254_RS13255 516d192e67f8abfdaaa2cf92a29af2dd 200 SUPERFAMILY SSF46785 54 138 2.19E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS13255 516d192e67f8abfdaaa2cf92a29af2dd 200 Gene3D G3DSA:1.10.10.10 50 190 1.6E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS13255 516d192e67f8abfdaaa2cf92a29af2dd 200 Pfam PF03551 Transcriptional regulator PadR-like family 58 125 1.3E-19 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CU254_RS18695 ce40714da4a7bc0879ace130228915a6 241 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 238 1.7E-61 T 28-03-2018 CU254_RS18695 ce40714da4a7bc0879ace130228915a6 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 6.4E-47 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18695 ce40714da4a7bc0879ace130228915a6 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 6.4E-47 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18695 ce40714da4a7bc0879ace130228915a6 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 203 223 6.4E-47 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18695 ce40714da4a7bc0879ace130228915a6 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 6.4E-47 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18695 ce40714da4a7bc0879ace130228915a6 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 6.4E-47 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18695 ce40714da4a7bc0879ace130228915a6 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 6.4E-47 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18695 ce40714da4a7bc0879ace130228915a6 241 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 185 1.9E-5 T 28-03-2018 CU254_RS18695 ce40714da4a7bc0879ace130228915a6 241 SUPERFAMILY SSF51735 5 240 8.15E-79 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS18695 ce40714da4a7bc0879ace130228915a6 241 Gene3D G3DSA:3.40.50.720 1 241 1.4E-72 T 28-03-2018 CU254_RS18695 ce40714da4a7bc0879ace130228915a6 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 7.2E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18695 ce40714da4a7bc0879ace130228915a6 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 7.2E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18695 ce40714da4a7bc0879ace130228915a6 241 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 7.2E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18695 ce40714da4a7bc0879ace130228915a6 241 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 136 164 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS21185 5c496d3d90ba359361b61ff2ba71d0b8 261 PRINTS PR00046 Major sigma-70 factor signature 64 77 2.2E-8 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS21185 5c496d3d90ba359361b61ff2ba71d0b8 261 PRINTS PR00046 Major sigma-70 factor signature 227 242 2.2E-8 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS21185 5c496d3d90ba359361b61ff2ba71d0b8 261 PRINTS PR00046 Major sigma-70 factor signature 242 253 2.2E-8 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS21185 5c496d3d90ba359361b61ff2ba71d0b8 261 PRINTS PR00046 Major sigma-70 factor signature 210 222 2.2E-8 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS21185 5c496d3d90ba359361b61ff2ba71d0b8 261 Gene3D G3DSA:1.10.10.10 196 254 4.2E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS21185 5c496d3d90ba359361b61ff2ba71d0b8 261 SUPERFAMILY SSF88946 9 109 4.45E-28 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS21185 5c496d3d90ba359361b61ff2ba71d0b8 261 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 35 257 5.9E-89 T 28-03-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS21185 5c496d3d90ba359361b61ff2ba71d0b8 261 SUPERFAMILY SSF88659 178 258 4.86E-17 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS21185 5c496d3d90ba359361b61ff2ba71d0b8 261 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 36 257 1.2E-34 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS21185 5c496d3d90ba359361b61ff2ba71d0b8 261 Gene3D G3DSA:1.10.601.10 15 108 1.2E-18 T 28-03-2018 CU254_RS21185 5c496d3d90ba359361b61ff2ba71d0b8 261 Pfam PF04542 Sigma-70 region 2 40 109 1.1E-15 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS21185 5c496d3d90ba359361b61ff2ba71d0b8 261 Gene3D G3DSA:1.10.10.10 110 162 4.5E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS21185 5c496d3d90ba359361b61ff2ba71d0b8 261 SUPERFAMILY SSF88659 113 187 1.61E-14 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS21185 5c496d3d90ba359361b61ff2ba71d0b8 261 Pfam PF04545 Sigma-70, region 4 206 255 2.3E-16 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS21185 5c496d3d90ba359361b61ff2ba71d0b8 261 Pfam PF04539 Sigma-70 region 3 124 186 9.4E-12 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS37800 e84e6cfa315118e77b88eb161229cb9a 226 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 2.4E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS37800 e84e6cfa315118e77b88eb161229cb9a 226 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 58 69 2.4E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS37800 e84e6cfa315118e77b88eb161229cb9a 226 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 104 120 2.4E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS37800 e84e6cfa315118e77b88eb161229cb9a 226 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 203 2.4E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS37800 e84e6cfa315118e77b88eb161229cb9a 226 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 167 2.4E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS37800 e84e6cfa315118e77b88eb161229cb9a 226 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 149 2.4E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS37800 e84e6cfa315118e77b88eb161229cb9a 226 Gene3D G3DSA:3.40.50.720 37 226 4.5E-58 T 28-03-2018 CU254_RS37800 e84e6cfa315118e77b88eb161229cb9a 226 Gene3D G3DSA:3.40.50.720 1 36 7.3E-6 T 28-03-2018 CU254_RS37800 e84e6cfa315118e77b88eb161229cb9a 226 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 149 1.0E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS37800 e84e6cfa315118e77b88eb161229cb9a 226 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 58 69 1.0E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS37800 e84e6cfa315118e77b88eb161229cb9a 226 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 110 118 1.0E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS37800 e84e6cfa315118e77b88eb161229cb9a 226 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 8 220 1.3E-52 T 28-03-2018 CU254_RS37800 e84e6cfa315118e77b88eb161229cb9a 226 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 117 145 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS37800 e84e6cfa315118e77b88eb161229cb9a 226 SUPERFAMILY SSF51735 2 221 1.23E-69 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS00785 0edd25b0f50e59c1ec306fd5046b0f00 181 Pfam PF11706 CGNR zinc finger 136 177 2.0E-17 T 28-03-2018 IPR021005 Zinc finger, CGNR CU254_RS00785 0edd25b0f50e59c1ec306fd5046b0f00 181 Pfam PF07336 Putative stress-induced transcription regulator 11 132 3.6E-17 T 28-03-2018 IPR010852 Putative stress-induced transcription regulator CU254_RS00785 0edd25b0f50e59c1ec306fd5046b0f00 181 SUPERFAMILY SSF160904 5 177 6.67E-42 T 28-03-2018 CU254_RS00785 0edd25b0f50e59c1ec306fd5046b0f00 181 Gene3D G3DSA:1.10.3300.10 4 180 1.0E-45 T 28-03-2018 IPR023286 ABATE domain CU254_RS35130 5fda290a737c420a261366619171cdd6 128 Pfam PF00313 'Cold-shock' DNA-binding domain 3 63 4.9E-14 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CU254_RS35130 5fda290a737c420a261366619171cdd6 128 PRINTS PR00050 Cold shock protein signature 4 19 6.2E-11 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CU254_RS35130 5fda290a737c420a261366619171cdd6 128 PRINTS PR00050 Cold shock protein signature 38 56 6.2E-11 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CU254_RS35130 5fda290a737c420a261366619171cdd6 128 PRINTS PR00050 Cold shock protein signature 24 33 6.2E-11 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CU254_RS35130 5fda290a737c420a261366619171cdd6 128 Gene3D G3DSA:2.40.50.140 2 74 1.5E-16 T 28-03-2018 CU254_RS35130 5fda290a737c420a261366619171cdd6 128 SMART SM00357 3 65 5.3E-20 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 CU254_RS35130 5fda290a737c420a261366619171cdd6 128 SUPERFAMILY SSF50249 2 65 3.92E-15 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CU254_RS25710 5d0d2e0c9bf87a41b6b86ccd8a1bcf36 136 Gene3D G3DSA:3.20.20.100 1 90 1.3E-14 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS25710 5d0d2e0c9bf87a41b6b86ccd8a1bcf36 136 SUPERFAMILY SSF51430 5 88 2.23E-14 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS25710 5d0d2e0c9bf87a41b6b86ccd8a1bcf36 136 Pfam PF00248 Aldo/keto reductase family 18 80 1.4E-9 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS19050 c8d161c92dfa173c28de1c14b3046c7f 201 SUPERFAMILY SSF48498 87 185 8.9E-8 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS19050 c8d161c92dfa173c28de1c14b3046c7f 201 ProSitePatterns PS01081 TetR-type HTH domain signature. 32 63 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CU254_RS19050 c8d161c92dfa173c28de1c14b3046c7f 201 Gene3D G3DSA:1.10.10.60 2 66 2.1E-20 T 28-03-2018 CU254_RS19050 c8d161c92dfa173c28de1c14b3046c7f 201 SUPERFAMILY SSF46689 7 90 2.28E-19 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS19050 c8d161c92dfa173c28de1c14b3046c7f 201 Gene3D G3DSA:1.10.357.10 67 196 1.0E-17 T 28-03-2018 CU254_RS19050 c8d161c92dfa173c28de1c14b3046c7f 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 65 2.9E-17 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS19050 c8d161c92dfa173c28de1c14b3046c7f 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 3.2E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS19050 c8d161c92dfa173c28de1c14b3046c7f 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 3.2E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS30565 19f78e84cdebc4c7f2263d7ce7aa7f3d 240 Gene3D G3DSA:3.50.30.40 13 193 3.2E-40 T 28-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CU254_RS30565 19f78e84cdebc4c7f2263d7ce7aa7f3d 240 Pfam PF03737 Aldolase/RraA 37 172 2.0E-23 T 28-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CU254_RS30565 19f78e84cdebc4c7f2263d7ce7aa7f3d 240 SUPERFAMILY SSF89562 30 182 3.01E-31 T 28-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CU254_RS29255 ea78f9f965c774b2a00f5407412a4fb8 542 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 353 369 1.4E-38 T 28-03-2018 CU254_RS29255 ea78f9f965c774b2a00f5407412a4fb8 542 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 335 353 1.4E-38 T 28-03-2018 CU254_RS29255 ea78f9f965c774b2a00f5407412a4fb8 542 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 10 32 1.4E-38 T 28-03-2018 CU254_RS29255 ea78f9f965c774b2a00f5407412a4fb8 542 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 317 333 1.4E-38 T 28-03-2018 CU254_RS29255 ea78f9f965c774b2a00f5407412a4fb8 542 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 176 191 1.4E-38 T 28-03-2018 CU254_RS29255 ea78f9f965c774b2a00f5407412a4fb8 542 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 302 317 1.4E-38 T 28-03-2018 CU254_RS29255 ea78f9f965c774b2a00f5407412a4fb8 542 Gene3D G3DSA:3.50.50.60 4 417 1.2E-62 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS29255 ea78f9f965c774b2a00f5407412a4fb8 542 SUPERFAMILY SSF51905 289 382 2.24E-56 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS29255 ea78f9f965c774b2a00f5407412a4fb8 542 SUPERFAMILY SSF51905 9 197 2.24E-56 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS29255 ea78f9f965c774b2a00f5407412a4fb8 542 Pfam PF01494 FAD binding domain 9 367 1.1E-72 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CU254_RS36260 2118b4a33f912b96cb3a29393c08ac36 284 Gene3D G3DSA:1.10.1740.10 2 78 4.8E-16 T 28-03-2018 CU254_RS36260 2118b4a33f912b96cb3a29393c08ac36 284 Gene3D G3DSA:3.10.450.50 151 276 1.7E-12 T 28-03-2018 CU254_RS36260 2118b4a33f912b96cb3a29393c08ac36 284 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 7 160 1.4E-16 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS36260 2118b4a33f912b96cb3a29393c08ac36 284 SUPERFAMILY SSF88659 102 160 2.99E-10 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS36260 2118b4a33f912b96cb3a29393c08ac36 284 Pfam PF04542 Sigma-70 region 2 11 75 2.9E-14 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS36260 2118b4a33f912b96cb3a29393c08ac36 284 SUPERFAMILY SSF88946 3 87 4.71E-15 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS36260 2118b4a33f912b96cb3a29393c08ac36 284 SUPERFAMILY SSF54427 172 271 1.76E-8 T 28-03-2018 IPR032710 NTF2-like domain CU254_RS36260 2118b4a33f912b96cb3a29393c08ac36 284 Gene3D G3DSA:1.10.10.10 85 150 7.9E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS36260 2118b4a33f912b96cb3a29393c08ac36 284 Pfam PF08281 Sigma-70, region 4 111 158 4.5E-9 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS30905 4f3ca4e510ceab4d99dac56f023d9bb7 291 SUPERFAMILY SSF53850 89 280 7.41E-27 T 28-03-2018 CU254_RS30905 4f3ca4e510ceab4d99dac56f023d9bb7 291 Gene3D G3DSA:3.40.190.10 179 253 2.2E-5 T 28-03-2018 CU254_RS30905 4f3ca4e510ceab4d99dac56f023d9bb7 291 Gene3D G3DSA:1.10.10.10 1 78 1.7E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS30905 4f3ca4e510ceab4d99dac56f023d9bb7 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 9.3E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS30905 4f3ca4e510ceab4d99dac56f023d9bb7 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 9.3E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS30905 4f3ca4e510ceab4d99dac56f023d9bb7 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 9.3E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS30905 4f3ca4e510ceab4d99dac56f023d9bb7 291 Pfam PF03466 LysR substrate binding domain 88 276 1.5E-26 T 28-03-2018 IPR005119 LysR, substrate-binding CU254_RS30905 4f3ca4e510ceab4d99dac56f023d9bb7 291 Gene3D G3DSA:3.40.190.10 79 178 1.5E-25 T 28-03-2018 CU254_RS30905 4f3ca4e510ceab4d99dac56f023d9bb7 291 SUPERFAMILY SSF46785 2 84 6.9E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS30905 4f3ca4e510ceab4d99dac56f023d9bb7 291 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 5.6E-22 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS35040 aa221c7a74cb0439722c4946e3163bf2 278 Pfam PF11268 Protein of unknown function (DUF3071) 1 169 3.1E-62 T 28-03-2018 IPR021421 Protein of unknown function DUF3071 CU254_RS37560 25485e9504cc31dde46be302862cc7b9 552 SUPERFAMILY SSF52540 1 234 7.78E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS37560 25485e9504cc31dde46be302862cc7b9 552 SUPERFAMILY SSF52540 300 522 3.0E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS37560 25485e9504cc31dde46be302862cc7b9 552 SMART SM00382 330 510 1.1E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS37560 25485e9504cc31dde46be302862cc7b9 552 SMART SM00382 28 220 1.9E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS37560 25485e9504cc31dde46be302862cc7b9 552 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS37560 25485e9504cc31dde46be302862cc7b9 552 Pfam PF00005 ABC transporter 322 462 2.8E-19 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS37560 25485e9504cc31dde46be302862cc7b9 552 Pfam PF00005 ABC transporter 19 170 1.1E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS37560 25485e9504cc31dde46be302862cc7b9 552 Gene3D G3DSA:3.40.50.300 1 276 1.2E-59 T 28-03-2018 CU254_RS37560 25485e9504cc31dde46be302862cc7b9 552 Gene3D G3DSA:3.40.50.300 302 532 7.8E-50 T 28-03-2018 CU254_RS39860 e4f18c42d4b893311ae5b5e6fa6d0731 1224 SUPERFAMILY SSF53756 507 777 5.76E-29 T 28-03-2018 CU254_RS39860 e4f18c42d4b893311ae5b5e6fa6d0731 1224 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 1022 1162 3.6E-23 T 28-03-2018 IPR006342 Methyltransferase FkbM CU254_RS39860 e4f18c42d4b893311ae5b5e6fa6d0731 1224 Gene3D G3DSA:3.40.50.2000 571 761 2.6E-26 T 28-03-2018 CU254_RS39860 e4f18c42d4b893311ae5b5e6fa6d0731 1224 Gene3D G3DSA:3.40.50.150 1007 1204 2.2E-28 T 28-03-2018 CU254_RS39860 e4f18c42d4b893311ae5b5e6fa6d0731 1224 Gene3D G3DSA:1.20.5.320 855 967 6.3E-4 T 28-03-2018 CU254_RS39860 e4f18c42d4b893311ae5b5e6fa6d0731 1224 Pfam PF00534 Glycosyl transferases group 1 590 702 5.7E-10 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CU254_RS39860 e4f18c42d4b893311ae5b5e6fa6d0731 1224 SUPERFAMILY SSF53448 5 258 3.09E-10 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS39860 e4f18c42d4b893311ae5b5e6fa6d0731 1224 Gene3D G3DSA:3.90.550.10 7 285 2.9E-13 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS39860 e4f18c42d4b893311ae5b5e6fa6d0731 1224 Pfam PF05050 Methyltransferase FkbM domain 1024 1186 1.0E-12 T 28-03-2018 IPR006342 Methyltransferase FkbM CU254_RS39860 e4f18c42d4b893311ae5b5e6fa6d0731 1224 SUPERFAMILY SSF53335 990 1193 4.94E-38 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS09310 ab5f08b26c0e94ea504132135c607d07 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 69 2.1E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS09310 ab5f08b26c0e94ea504132135c607d07 201 Gene3D G3DSA:1.10.10.60 3 54 1.3E-19 T 28-03-2018 CU254_RS09310 ab5f08b26c0e94ea504132135c607d07 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 1.3E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS09310 ab5f08b26c0e94ea504132135c607d07 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 1.3E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS09310 ab5f08b26c0e94ea504132135c607d07 201 SUPERFAMILY SSF48498 90 199 7.11E-27 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS09310 ab5f08b26c0e94ea504132135c607d07 201 Gene3D G3DSA:1.10.260.40 55 87 0.004 T 28-03-2018 CU254_RS09310 ab5f08b26c0e94ea504132135c607d07 201 Gene3D G3DSA:1.10.357.10 88 200 2.9E-32 T 28-03-2018 CU254_RS09310 ab5f08b26c0e94ea504132135c607d07 201 SUPERFAMILY SSF46689 10 74 3.54E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS25020 4f9fab033537988c613f1b47827b766f 139 Gene3D G3DSA:3.10.450.50 3 138 3.5E-31 T 28-03-2018 CU254_RS25020 4f9fab033537988c613f1b47827b766f 139 SUPERFAMILY SSF54427 5 137 1.72E-29 T 28-03-2018 IPR032710 NTF2-like domain CU254_RS25020 4f9fab033537988c613f1b47827b766f 139 Pfam PF13577 SnoaL-like domain 6 134 1.3E-20 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CU254_RS13290 0b0e417021eba317aa80af4be5311a74 468 Pfam PF02952 L-fucose isomerase, C-terminal domain 329 465 6.9E-37 T 28-03-2018 IPR015888 L-fucose isomerase, C-terminal GO:0005737|GO:0006004|GO:0008736 KEGG: 00051+5.3.1.25 CU254_RS13290 0b0e417021eba317aa80af4be5311a74 468 Pfam PF07882 L-fucose isomerase, second N-terminal domain 251 309 4.6E-10 T 28-03-2018 IPR012889 L-fucose isomerase, N-terminal-2 GO:0005737|GO:0006004|GO:0008736 KEGG: 00051+5.3.1.25 CU254_RS13290 0b0e417021eba317aa80af4be5311a74 468 Pfam PF07881 L-fucose isomerase, first N-terminal domain 2 154 4.1E-18 T 28-03-2018 IPR012888 L-fucose isomerase, N-terminal-1 GO:0005737|GO:0006004|GO:0008736 KEGG: 00051+5.3.1.25 CU254_RS13290 0b0e417021eba317aa80af4be5311a74 468 SUPERFAMILY SSF53743 2 310 8.63E-80 T 28-03-2018 IPR009015 L-fucose isomerase, N-terminal/central domain GO:0005737|GO:0005996|GO:0016861 CU254_RS13290 0b0e417021eba317aa80af4be5311a74 468 Gene3D G3DSA:3.20.14.10 297 331 4.3E-4 T 28-03-2018 CU254_RS13290 0b0e417021eba317aa80af4be5311a74 468 Gene3D G3DSA:3.20.14.10 332 466 9.0E-32 T 28-03-2018 CU254_RS13290 0b0e417021eba317aa80af4be5311a74 468 Gene3D G3DSA:3.40.275.10 157 294 6.6E-41 T 28-03-2018 CU254_RS13290 0b0e417021eba317aa80af4be5311a74 468 SUPERFAMILY SSF50443 313 461 8.63E-6 T 28-03-2018 IPR004216 L-fucose/L-arabinose isomerase, C-terminal CU254_RS13290 0b0e417021eba317aa80af4be5311a74 468 Gene3D G3DSA:3.40.50.1070 1 155 7.0E-36 T 28-03-2018 CU254_RS21620 4651a37ecb4f7f11cc033d623a535e0a 380 Gene3D G3DSA:3.40.50.2000 180 348 1.1E-39 T 28-03-2018 CU254_RS21620 4651a37ecb4f7f11cc033d623a535e0a 380 Gene3D G3DSA:3.40.50.2000 5 179 3.7E-15 T 28-03-2018 CU254_RS21620 4651a37ecb4f7f11cc033d623a535e0a 380 SUPERFAMILY SSF53756 3 365 2.09E-74 T 28-03-2018 CU254_RS21620 4651a37ecb4f7f11cc033d623a535e0a 380 Pfam PF13439 Glycosyltransferase Family 4 14 172 2.7E-26 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CU254_RS21620 4651a37ecb4f7f11cc033d623a535e0a 380 Pfam PF13692 Glycosyl transferases group 1 190 330 1.3E-27 T 28-03-2018 CU254_RS18515 b752eda0642b998b0d2e7e7c8b8e71db 242 Gene3D G3DSA:3.40.50.1820 9 238 3.5E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS18515 b752eda0642b998b0d2e7e7c8b8e71db 242 Pfam PF00561 alpha/beta hydrolase fold 19 123 9.1E-12 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS18515 b752eda0642b998b0d2e7e7c8b8e71db 242 SUPERFAMILY SSF53474 17 220 1.75E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS08375 d825ee87c0e312ad19def7f642d5a642 285 Gene3D G3DSA:3.90.230.10 30 285 2.2E-86 T 28-03-2018 CU254_RS08375 d825ee87c0e312ad19def7f642d5a642 285 SUPERFAMILY SSF55920 5 284 9.42E-86 T 28-03-2018 IPR000994 Peptidase M24 CU254_RS08375 d825ee87c0e312ad19def7f642d5a642 285 Pfam PF00557 Metallopeptidase family M24 48 276 1.9E-51 T 28-03-2018 IPR000994 Peptidase M24 CU254_RS08375 d825ee87c0e312ad19def7f642d5a642 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 227 239 7.2E-21 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CU254_RS08375 d825ee87c0e312ad19def7f642d5a642 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 126 142 7.2E-21 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CU254_RS08375 d825ee87c0e312ad19def7f642d5a642 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 104 117 7.2E-21 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CU254_RS08375 d825ee87c0e312ad19def7f642d5a642 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 196 208 7.2E-21 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CU254_RS08375 d825ee87c0e312ad19def7f642d5a642 285 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 202 220 - T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CU254_RS08375 d825ee87c0e312ad19def7f642d5a642 285 Hamap MF_01974 Methionine aminopeptidase [map]. 39 285 39.925 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CU254_RS08375 d825ee87c0e312ad19def7f642d5a642 285 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 42 283 1.5E-88 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CU254_RS36610 050055ee612ac05a937a8a0bc7a03335 435 ProSitePatterns PS00217 Sugar transport proteins signature 2. 119 144 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CU254_RS36610 050055ee612ac05a937a8a0bc7a03335 435 Gene3D G3DSA:1.20.1250.20 4 216 3.8E-24 T 28-03-2018 CU254_RS36610 050055ee612ac05a937a8a0bc7a03335 435 Gene3D G3DSA:1.20.1250.20 217 434 3.0E-28 T 28-03-2018 CU254_RS36610 050055ee612ac05a937a8a0bc7a03335 435 Pfam PF07690 Major Facilitator Superfamily 45 375 5.4E-26 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS36610 050055ee612ac05a937a8a0bc7a03335 435 SUPERFAMILY SSF103473 7 424 1.44E-64 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS22710 2d6168c57201900eb38a55477fdfd9cb 268 Gene3D G3DSA:1.10.10.60 207 249 1.9E-9 T 28-03-2018 CU254_RS22710 2d6168c57201900eb38a55477fdfd9cb 268 Pfam PF12833 Helix-turn-helix domain 175 247 6.6E-15 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS22710 2d6168c57201900eb38a55477fdfd9cb 268 Gene3D G3DSA:1.10.10.60 169 206 5.1E-4 T 28-03-2018 CU254_RS22710 2d6168c57201900eb38a55477fdfd9cb 268 SMART SM00342 167 247 5.0E-9 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS22710 2d6168c57201900eb38a55477fdfd9cb 268 SUPERFAMILY SSF46689 202 247 7.62E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS20300 5d4bbe2c017f9c65ab6b35e36a4792d5 101 SUPERFAMILY SSF57716 2 101 6.42E-33 T 28-03-2018 CU254_RS20300 5d4bbe2c017f9c65ab6b35e36a4792d5 101 Gene3D G3DSA:4.10.830.10 1 101 7.9E-31 T 28-03-2018 CU254_RS20300 5d4bbe2c017f9c65ab6b35e36a4792d5 101 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 101 25.966 T 28-03-2018 IPR023036 Ribosomal protein S14, bacterial/plastid CU254_RS20300 5d4bbe2c017f9c65ab6b35e36a4792d5 101 Pfam PF00253 Ribosomal protein S14p/S29e 48 100 1.9E-24 T 28-03-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS11170 497dfd9fa62e8ad51b43dec704d8c5fd 309 Gene3D G3DSA:3.20.20.220 4 308 4.0E-73 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like CU254_RS11170 497dfd9fa62e8ad51b43dec704d8c5fd 309 SUPERFAMILY SSF51730 35 303 9.02E-70 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like CU254_RS11170 497dfd9fa62e8ad51b43dec704d8c5fd 309 Pfam PF01619 Proline dehydrogenase 43 300 1.3E-33 T 28-03-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 CU254_RS11170 497dfd9fa62e8ad51b43dec704d8c5fd 309 PIRSF PIRSF000196 1 309 9.0E-112 T 28-03-2018 IPR008219 Proline dehydrogenase, bacteria and archaea GO:0004657|GO:0010133 KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 CU254_RS27440 935aec51cc7766b9a1aba9d61f02e26d 120 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 5.3E-10 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS27440 935aec51cc7766b9a1aba9d61f02e26d 120 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 5.3E-10 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS27440 935aec51cc7766b9a1aba9d61f02e26d 120 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 5.3E-10 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS27440 935aec51cc7766b9a1aba9d61f02e26d 120 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS27440 935aec51cc7766b9a1aba9d61f02e26d 120 Gene3D G3DSA:1.10.1660.10 1 54 3.8E-22 T 28-03-2018 CU254_RS27440 935aec51cc7766b9a1aba9d61f02e26d 120 SUPERFAMILY SSF46955 2 112 3.44E-26 T 28-03-2018 IPR009061 Putative DNA-binding domain CU254_RS27440 935aec51cc7766b9a1aba9d61f02e26d 120 SMART SM00422 1 69 2.2E-21 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS27440 935aec51cc7766b9a1aba9d61f02e26d 120 Pfam PF13411 MerR HTH family regulatory protein 2 67 3.0E-17 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS27440 935aec51cc7766b9a1aba9d61f02e26d 120 Gene3D G3DSA:1.10.1660.10 55 118 1.1E-8 T 28-03-2018 CU254_RS35065 e375c5be431830762604bad670d9c5c9 200 Gene3D G3DSA:1.10.357.10 73 200 1.8E-17 T 28-03-2018 CU254_RS35065 e375c5be431830762604bad670d9c5c9 200 Gene3D G3DSA:1.10.10.60 8 52 2.7E-15 T 28-03-2018 CU254_RS35065 e375c5be431830762604bad670d9c5c9 200 ProSitePatterns PS01081 TetR-type HTH domain signature. 32 63 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CU254_RS35065 e375c5be431830762604bad670d9c5c9 200 SUPERFAMILY SSF48498 87 195 1.1E-9 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS35065 e375c5be431830762604bad670d9c5c9 200 Gene3D G3DSA:1.10.10.60 53 72 9.5E-13 T 28-03-2018 CU254_RS35065 e375c5be431830762604bad670d9c5c9 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 65 1.4E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS35065 e375c5be431830762604bad670d9c5c9 200 SUPERFAMILY SSF46689 11 83 7.77E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS35065 e375c5be431830762604bad670d9c5c9 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 7.0E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS35065 e375c5be431830762604bad670d9c5c9 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 7.0E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS10830 562aacc0c9073b8efa5b0be247b86b04 559 Gene3D G3DSA:3.40.190.10 215 307 6.1E-23 T 28-03-2018 CU254_RS10830 562aacc0c9073b8efa5b0be247b86b04 559 Gene3D G3DSA:3.10.105.10 308 528 9.3E-48 T 28-03-2018 CU254_RS10830 562aacc0c9073b8efa5b0be247b86b04 559 SUPERFAMILY SSF53850 51 550 2.71E-76 T 28-03-2018 CU254_RS10830 562aacc0c9073b8efa5b0be247b86b04 559 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 107 460 4.5E-59 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CU254_RS10830 562aacc0c9073b8efa5b0be247b86b04 559 Gene3D G3DSA:3.90.76.10 59 214 8.7E-15 T 28-03-2018 CU254_RS38155 e74c087bf34b6d0da2d663bcf88b33cb 288 Gene3D G3DSA:3.40.1190.20 1 286 3.1E-50 T 28-03-2018 IPR029056 Ribokinase-like CU254_RS38155 e74c087bf34b6d0da2d663bcf88b33cb 288 SUPERFAMILY SSF53613 1 279 2.96E-43 T 28-03-2018 IPR029056 Ribokinase-like CU254_RS38155 e74c087bf34b6d0da2d663bcf88b33cb 288 Pfam PF00294 pfkB family carbohydrate kinase 4 270 6.4E-29 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CU254_RS36095 8fd1f822c8d134e91c297d90dd4476f6 481 Pfam PF16822 SGNH hydrolase-like domain, acetyltransferase AlgX 195 413 7.8E-18 T 28-03-2018 IPR031811 AlgX/AlgJ, SGNH hydrolase-like domain CU254_RS34400 4a758d3422bd97dcc2c4f454f6790509 116 Pfam PF03992 Antibiotic biosynthesis monooxygenase 23 96 2.4E-16 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain CU254_RS34400 4a758d3422bd97dcc2c4f454f6790509 116 Gene3D G3DSA:3.30.70.100 21 116 1.1E-21 T 28-03-2018 CU254_RS34400 4a758d3422bd97dcc2c4f454f6790509 116 SUPERFAMILY SSF54909 18 108 5.11E-23 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS09430 f5eb8067a9a044677b2a6a12d7b54b22 671 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 142 154 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CU254_RS09430 f5eb8067a9a044677b2a6a12d7b54b22 671 Gene3D G3DSA:3.30.200.20 3 117 4.5E-22 T 28-03-2018 CU254_RS09430 f5eb8067a9a044677b2a6a12d7b54b22 671 Pfam PF03793 PASTA domain 544 602 7.8E-11 T 28-03-2018 IPR005543 PASTA domain CU254_RS09430 f5eb8067a9a044677b2a6a12d7b54b22 671 Pfam PF03793 PASTA domain 473 536 4.0E-12 T 28-03-2018 IPR005543 PASTA domain CU254_RS09430 f5eb8067a9a044677b2a6a12d7b54b22 671 Pfam PF03793 PASTA domain 408 469 2.3E-13 T 28-03-2018 IPR005543 PASTA domain CU254_RS09430 f5eb8067a9a044677b2a6a12d7b54b22 671 Pfam PF03793 PASTA domain 605 666 3.1E-8 T 28-03-2018 IPR005543 PASTA domain CU254_RS09430 f5eb8067a9a044677b2a6a12d7b54b22 671 SUPERFAMILY SSF56112 15 359 4.1E-74 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS09430 f5eb8067a9a044677b2a6a12d7b54b22 671 Pfam PF00069 Protein kinase domain 17 279 7.3E-45 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CU254_RS09430 f5eb8067a9a044677b2a6a12d7b54b22 671 SMART SM00740 403 469 5.3E-14 T 28-03-2018 IPR005543 PASTA domain CU254_RS09430 f5eb8067a9a044677b2a6a12d7b54b22 671 SMART SM00740 605 671 0.031 T 28-03-2018 IPR005543 PASTA domain CU254_RS09430 f5eb8067a9a044677b2a6a12d7b54b22 671 SMART SM00740 538 603 6.6E-6 T 28-03-2018 IPR005543 PASTA domain CU254_RS09430 f5eb8067a9a044677b2a6a12d7b54b22 671 SMART SM00740 470 536 1.0E-8 T 28-03-2018 IPR005543 PASTA domain CU254_RS09430 f5eb8067a9a044677b2a6a12d7b54b22 671 SMART SM00220 17 281 2.0E-57 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CU254_RS09430 f5eb8067a9a044677b2a6a12d7b54b22 671 Gene3D G3DSA:1.10.510.10 118 316 1.8E-45 T 28-03-2018 CU254_RS09040 346b55c2160e40f13ab4906f12519dd8 113 SUPERFAMILY SSF140453 6 98 2.09E-12 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CU254_RS09040 346b55c2160e40f13ab4906f12519dd8 113 Pfam PF06013 Proteins of 100 residues with WXG 6 89 1.4E-7 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CU254_RS09040 346b55c2160e40f13ab4906f12519dd8 113 Gene3D G3DSA:1.10.287.1060 2 99 6.6E-12 T 28-03-2018 CU254_RS24120 7d1f916033c25083d74e120117615bd5 169 SUPERFAMILY SSF54427 8 169 5.31E-53 T 28-03-2018 IPR032710 NTF2-like domain CU254_RS24120 7d1f916033c25083d74e120117615bd5 169 Gene3D G3DSA:3.10.450.50 5 169 5.7E-29 T 28-03-2018 CU254_RS24120 7d1f916033c25083d74e120117615bd5 169 TIGRFAM TIGR03232 benzo_1_2_benB: benzoate 1,2-dioxygenase, small subunit 14 168 1.5E-80 T 28-03-2018 IPR017641 Benzoate 1,2-dioxygenase, small subunit GO:0016708|GO:0055114 CU254_RS24120 7d1f916033c25083d74e120117615bd5 169 Pfam PF00866 Ring hydroxylating beta subunit 20 161 6.7E-44 T 28-03-2018 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0003824|GO:0006725|GO:0055114 CU254_RS01730 5de158d7b6a40eadf3efdb0c8f97e138 144 Gene3D G3DSA:3.30.1550.10 6 74 2.2E-34 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal CU254_RS01730 5de158d7b6a40eadf3efdb0c8f97e138 144 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 39 71 2.0E-12 T 28-03-2018 CU254_RS01730 5de158d7b6a40eadf3efdb0c8f97e138 144 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 6 143 1.2E-62 T 28-03-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS01730 5de158d7b6a40eadf3efdb0c8f97e138 144 Gene3D G3DSA:1.10.10.250 75 143 2.5E-26 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CU254_RS01730 5de158d7b6a40eadf3efdb0c8f97e138 144 Pfam PF03946 Ribosomal protein L11, N-terminal domain 12 69 1.9E-28 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal CU254_RS01730 5de158d7b6a40eadf3efdb0c8f97e138 144 ProSitePatterns PS00359 Ribosomal protein L11 signature. 129 144 - T 28-03-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS01730 5de158d7b6a40eadf3efdb0c8f97e138 144 SUPERFAMILY SSF54747 5 75 1.02E-28 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal CU254_RS01730 5de158d7b6a40eadf3efdb0c8f97e138 144 SUPERFAMILY SSF46906 70 143 8.24E-27 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CU254_RS01730 5de158d7b6a40eadf3efdb0c8f97e138 144 SMART SM00649 12 143 7.4E-84 T 28-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 CU254_RS01730 5de158d7b6a40eadf3efdb0c8f97e138 144 Pfam PF00298 Ribosomal protein L11, RNA binding domain 74 142 4.4E-27 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CU254_RS01730 5de158d7b6a40eadf3efdb0c8f97e138 144 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 8 144 31.53 T 28-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 CU254_RS37925 e66e22ec92f2aeeaab5b6c48ca8528d5 300 Gene3D G3DSA:3.20.20.30 1 295 6.9E-53 T 28-03-2018 CU254_RS37925 e66e22ec92f2aeeaab5b6c48ca8528d5 300 TIGRFAM TIGR03564 F420_MSMEG_4879: F420-dependent oxidoreductase, MSMEG_4879 family 20 273 4.7E-93 T 28-03-2018 IPR019910 Luciferase-like, F420-dependent oxidoreductase, MSMEG4879, predicted CU254_RS37925 e66e22ec92f2aeeaab5b6c48ca8528d5 300 Pfam PF00296 Luciferase-like monooxygenase 15 270 3.8E-44 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS37925 e66e22ec92f2aeeaab5b6c48ca8528d5 300 SUPERFAMILY SSF51679 1 294 7.95E-56 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS09400 97337fc20fa15bf9042aa5b6d1cf7f35 1056 Gene3D G3DSA:1.25.40.10 435 611 2.8E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS09400 97337fc20fa15bf9042aa5b6d1cf7f35 1056 Gene3D G3DSA:3.40.50.300 31 202 3.9E-4 T 28-03-2018 CU254_RS09400 97337fc20fa15bf9042aa5b6d1cf7f35 1056 Gene3D G3DSA:1.25.40.10 678 1002 4.9E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS12040 443c8de014f02d30e6d58049d2c78d21 201 Gene3D G3DSA:1.10.10.60 2 52 4.6E-20 T 28-03-2018 CU254_RS12040 443c8de014f02d30e6d58049d2c78d21 201 Gene3D G3DSA:1.10.10.60 53 196 1.4E-7 T 28-03-2018 CU254_RS12040 443c8de014f02d30e6d58049d2c78d21 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 63 3.1E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS12040 443c8de014f02d30e6d58049d2c78d21 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 1.5E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS12040 443c8de014f02d30e6d58049d2c78d21 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 1.5E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS12040 443c8de014f02d30e6d58049d2c78d21 201 SUPERFAMILY SSF46689 3 84 1.54E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS22265 8e301c20c54c4bdf972fbf28115bd464 160 SUPERFAMILY SSF116726 85 157 7.98E-18 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CU254_RS22265 8e301c20c54c4bdf972fbf28115bd464 160 Gene3D G3DSA:3.30.70.1450 87 160 3.5E-17 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CU254_RS22265 8e301c20c54c4bdf972fbf28115bd464 160 PIRSF PIRSF005028 1 160 2.1E-56 T 28-03-2018 IPR026278 Potassium/proton antiporter subunit KhtT CU254_RS22265 8e301c20c54c4bdf972fbf28115bd464 160 Pfam PF02080 TrkA-C domain 90 157 3.3E-16 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CU254_RS41310 326a8fd6b80090e343af61e037d67b68 425 SUPERFAMILY SSF48264 7 414 4.58E-59 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS41310 326a8fd6b80090e343af61e037d67b68 425 Gene3D G3DSA:1.10.630.10 22 422 2.7E-39 T 28-03-2018 CU254_RS41310 326a8fd6b80090e343af61e037d67b68 425 PRINTS PR00359 B-class P450 signature 304 331 3.1E-16 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS41310 326a8fd6b80090e343af61e037d67b68 425 PRINTS PR00359 B-class P450 signature 110 121 3.1E-16 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS41310 326a8fd6b80090e343af61e037d67b68 425 PRINTS PR00359 B-class P450 signature 352 361 3.1E-16 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS41310 326a8fd6b80090e343af61e037d67b68 425 PRINTS PR00359 B-class P450 signature 286 297 3.1E-16 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS41310 326a8fd6b80090e343af61e037d67b68 425 PRINTS PR00359 B-class P450 signature 156 172 3.1E-16 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS41310 326a8fd6b80090e343af61e037d67b68 425 PRINTS PR00359 B-class P450 signature 207 229 3.1E-16 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS34065 62dea104825966e6786172e0e513cf77 277 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 9.8E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS34065 62dea104825966e6786172e0e513cf77 277 Gene3D G3DSA:3.40.190.10 205 252 2.1E-4 T 28-03-2018 CU254_RS34065 62dea104825966e6786172e0e513cf77 277 Gene3D G3DSA:3.40.190.10 175 204 3.1E-4 T 28-03-2018 CU254_RS34065 62dea104825966e6786172e0e513cf77 277 Gene3D G3DSA:1.10.10.10 1 86 1.7E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS34065 62dea104825966e6786172e0e513cf77 277 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 1.6E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS34065 62dea104825966e6786172e0e513cf77 277 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 1.6E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS34065 62dea104825966e6786172e0e513cf77 277 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 1.6E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS34065 62dea104825966e6786172e0e513cf77 277 Pfam PF03466 LysR substrate binding domain 90 275 1.4E-17 T 28-03-2018 IPR005119 LysR, substrate-binding CU254_RS34065 62dea104825966e6786172e0e513cf77 277 SUPERFAMILY SSF53850 92 275 4.71E-18 T 28-03-2018 CU254_RS34065 62dea104825966e6786172e0e513cf77 277 Gene3D G3DSA:3.40.190.10 88 174 6.5E-13 T 28-03-2018 CU254_RS34065 62dea104825966e6786172e0e513cf77 277 SUPERFAMILY SSF46785 5 88 2.01E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS39970 fb7f84c791c5007cf857e8a6c3fab006 384 PRINTS PR00359 B-class P450 signature 129 145 6.4E-44 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS39970 fb7f84c791c5007cf857e8a6c3fab006 384 PRINTS PR00359 B-class P450 signature 261 272 6.4E-44 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS39970 fb7f84c791c5007cf857e8a6c3fab006 384 PRINTS PR00359 B-class P450 signature 306 321 6.4E-44 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS39970 fb7f84c791c5007cf857e8a6c3fab006 384 PRINTS PR00359 B-class P450 signature 336 347 6.4E-44 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS39970 fb7f84c791c5007cf857e8a6c3fab006 384 PRINTS PR00359 B-class P450 signature 79 90 6.4E-44 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS39970 fb7f84c791c5007cf857e8a6c3fab006 384 PRINTS PR00359 B-class P450 signature 278 305 6.4E-44 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS39970 fb7f84c791c5007cf857e8a6c3fab006 384 PRINTS PR00359 B-class P450 signature 146 161 6.4E-44 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS39970 fb7f84c791c5007cf857e8a6c3fab006 384 PRINTS PR00359 B-class P450 signature 327 336 6.4E-44 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS39970 fb7f84c791c5007cf857e8a6c3fab006 384 Pfam PF00067 Cytochrome P450 207 353 4.5E-21 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS39970 fb7f84c791c5007cf857e8a6c3fab006 384 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 329 338 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CU254_RS39970 fb7f84c791c5007cf857e8a6c3fab006 384 SUPERFAMILY SSF48264 6 383 8.91E-80 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS39970 fb7f84c791c5007cf857e8a6c3fab006 384 Gene3D G3DSA:1.10.630.10 1 384 3.5E-68 T 28-03-2018 CU254_RS16330 a6da5bc537bad6def4c5c9903c3ef0dc 312 Pfam PF00294 pfkB family carbohydrate kinase 19 300 1.1E-48 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CU254_RS16330 a6da5bc537bad6def4c5c9903c3ef0dc 312 SUPERFAMILY SSF53613 5 303 1.56E-67 T 28-03-2018 IPR029056 Ribokinase-like CU254_RS16330 a6da5bc537bad6def4c5c9903c3ef0dc 312 Gene3D G3DSA:3.40.1190.20 1 311 3.9E-62 T 28-03-2018 IPR029056 Ribokinase-like CU254_RS16330 a6da5bc537bad6def4c5c9903c3ef0dc 312 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 252 265 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CU254_RS32760 d6967f23d498556099ad5e3bf663b025 387 Gene3D G3DSA:3.60.21.10 3 71 2.1E-14 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CU254_RS32760 d6967f23d498556099ad5e3bf663b025 387 Gene3D G3DSA:3.60.21.10 72 271 3.9E-35 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CU254_RS32760 d6967f23d498556099ad5e3bf663b025 387 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 5 247 4.0E-48 T 28-03-2018 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 CU254_RS32760 d6967f23d498556099ad5e3bf663b025 387 Pfam PF00149 Calcineurin-like phosphoesterase 5 221 1.1E-12 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CU254_RS32760 d6967f23d498556099ad5e3bf663b025 387 SUPERFAMILY SSF56300 5 276 5.37E-52 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CU254_RS32760 d6967f23d498556099ad5e3bf663b025 387 Pfam PF12320 Type 5 capsule protein repressor C-terminal domain 270 357 2.1E-5 T 28-03-2018 IPR026843 Nuclease SbcCD subunit D, C-terminal domain CU254_RS00135 86d0ec3ca4b24247b141869e0320756e 457 SUPERFAMILY SSF53383 4 456 4.13E-103 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS00135 86d0ec3ca4b24247b141869e0320756e 457 Pfam PF01212 Beta-eliminating lyase 45 422 1.1E-66 T 28-03-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 CU254_RS00135 86d0ec3ca4b24247b141869e0320756e 457 Gene3D G3DSA:3.90.1150.10 271 454 1.9E-60 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS00135 86d0ec3ca4b24247b141869e0320756e 457 Gene3D G3DSA:3.90.1150.10 16 108 3.5E-21 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS32865 f64a90959572484fb6ed50e44da5afff 479 SUPERFAMILY SSF54631 98 202 9.22E-15 T 28-03-2018 CU254_RS32865 f64a90959572484fb6ed50e44da5afff 479 SUPERFAMILY SSF51412 203 473 7.33E-93 T 28-03-2018 CU254_RS32865 f64a90959572484fb6ed50e44da5afff 479 SUPERFAMILY SSF51412 11 93 7.33E-93 T 28-03-2018 CU254_RS32865 f64a90959572484fb6ed50e44da5afff 479 TIGRFAM TIGR01303 IMP_DH_rel_1: IMP dehydrogenase family protein 2 477 8.2E-244 T 28-03-2018 IPR005991 IMP dehydrogenase-related 1 CU254_RS32865 f64a90959572484fb6ed50e44da5afff 479 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 13 474 7.6E-105 T 28-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 CU254_RS32865 f64a90959572484fb6ed50e44da5afff 479 Pfam PF00571 CBS domain 100 137 0.0018 T 28-03-2018 IPR000644 CBS domain CU254_RS32865 f64a90959572484fb6ed50e44da5afff 479 Gene3D G3DSA:3.20.20.70 3 470 6.4E-84 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS32865 f64a90959572484fb6ed50e44da5afff 479 SMART SM01240 11 475 2.0E-190 T 28-03-2018 CU254_RS32865 f64a90959572484fb6ed50e44da5afff 479 PIRSF PIRSF000130 4 479 2.9E-140 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CU254_RS30810 223a8b8a68f743f5d71199f4b52a9ee1 402 Gene3D G3DSA:1.20.1250.20 204 394 1.0E-11 T 28-03-2018 CU254_RS30810 223a8b8a68f743f5d71199f4b52a9ee1 402 SUPERFAMILY SSF103473 17 392 5.89E-29 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS30810 223a8b8a68f743f5d71199f4b52a9ee1 402 Pfam PF05977 Transmembrane secretion effector 11 379 3.7E-14 T 28-03-2018 IPR010290 Transmembrane secretion effector CU254_RS30810 223a8b8a68f743f5d71199f4b52a9ee1 402 Gene3D G3DSA:1.20.1250.20 5 203 3.3E-16 T 28-03-2018 CU254_RS36235 75f11c72008350a9010ae7b9ab052c2c 275 SUPERFAMILY SSF46689 209 262 1.97E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS36235 75f11c72008350a9010ae7b9ab052c2c 275 Gene3D G3DSA:1.10.10.60 154 209 9.4E-10 T 28-03-2018 CU254_RS36235 75f11c72008350a9010ae7b9ab052c2c 275 Gene3D G3DSA:1.10.10.60 210 269 2.8E-13 T 28-03-2018 CU254_RS36235 75f11c72008350a9010ae7b9ab052c2c 275 Pfam PF12833 Helix-turn-helix domain 179 258 1.6E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS36235 75f11c72008350a9010ae7b9ab052c2c 275 SMART SM00342 173 257 2.1E-16 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS03240 0cfa95b4d4319807c3e10ee5bd27cdac 539 Gene3D G3DSA:1.20.1250.20 7 197 1.0E-37 T 28-03-2018 CU254_RS03240 0cfa95b4d4319807c3e10ee5bd27cdac 539 Gene3D G3DSA:1.20.1250.20 254 530 7.5E-35 T 28-03-2018 CU254_RS03240 0cfa95b4d4319807c3e10ee5bd27cdac 539 Pfam PF07690 Major Facilitator Superfamily 15 412 2.4E-63 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS03240 0cfa95b4d4319807c3e10ee5bd27cdac 539 SUPERFAMILY SSF103473 250 422 1.83E-80 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS03240 0cfa95b4d4319807c3e10ee5bd27cdac 539 SUPERFAMILY SSF103473 494 524 1.83E-80 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS03240 0cfa95b4d4319807c3e10ee5bd27cdac 539 SUPERFAMILY SSF103473 7 194 1.83E-80 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS03240 0cfa95b4d4319807c3e10ee5bd27cdac 539 PRINTS PR01036 Tetracycline resistance protein TetB signature 135 159 1.0E-7 T 28-03-2018 CU254_RS03240 0cfa95b4d4319807c3e10ee5bd27cdac 539 PRINTS PR01036 Tetracycline resistance protein TetB signature 200 218 1.0E-7 T 28-03-2018 CU254_RS03240 0cfa95b4d4319807c3e10ee5bd27cdac 539 PRINTS PR01036 Tetracycline resistance protein TetB signature 14 38 1.0E-7 T 28-03-2018 CU254_RS03240 0cfa95b4d4319807c3e10ee5bd27cdac 539 PRINTS PR01036 Tetracycline resistance protein TetB signature 105 125 1.0E-7 T 28-03-2018 CU254_RS03240 0cfa95b4d4319807c3e10ee5bd27cdac 539 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 12 433 1.7E-97 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CU254_RS28300 156144968e2c7561a64b66816e65875e 453 TIGRFAM TIGR03173 pbuX: xanthine permease 30 437 1.3E-139 T 28-03-2018 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 CU254_RS28300 156144968e2c7561a64b66816e65875e 453 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 23 435 2.9E-106 T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CU254_RS28300 156144968e2c7561a64b66816e65875e 453 Pfam PF00860 Permease family 25 402 1.8E-92 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CU254_RS28300 156144968e2c7561a64b66816e65875e 453 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 352 372 - T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CU254_RS02745 d731df02ef5e49853a0000855ba77813 271 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 8 265 1.3E-67 T 28-03-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 CU254_RS02745 d731df02ef5e49853a0000855ba77813 271 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 9 264 3.3E-65 T 28-03-2018 CU254_RS02745 d731df02ef5e49853a0000855ba77813 271 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 9 258 1.0E-16 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CU254_RS02745 d731df02ef5e49853a0000855ba77813 271 Gene3D G3DSA:3.60.10.10 5 270 1.2E-49 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CU254_RS02745 d731df02ef5e49853a0000855ba77813 271 SUPERFAMILY SSF56219 7 266 1.02E-67 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CU254_RS04075 f2659cd479da3eca1d9ed7bb0508cf1f 273 Gene3D G3DSA:2.40.30.10 2 135 1.4E-33 T 28-03-2018 CU254_RS04075 f2659cd479da3eca1d9ed7bb0508cf1f 273 SUPERFAMILY SSF63380 4 135 1.04E-12 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CU254_RS04075 f2659cd479da3eca1d9ed7bb0508cf1f 273 Pfam PF08021 Siderophore-interacting FAD-binding domain 11 134 2.0E-36 T 28-03-2018 IPR013113 FAD-binding 9, siderophore-interacting CU254_RS04075 f2659cd479da3eca1d9ed7bb0508cf1f 273 Gene3D G3DSA:3.40.50.80 137 273 7.4E-50 T 28-03-2018 CU254_RS04075 f2659cd479da3eca1d9ed7bb0508cf1f 273 Pfam PF04954 Siderophore-interacting protein 143 259 2.9E-43 T 28-03-2018 IPR007037 Siderophore-interacting protein CU254_RS16200 689f8e9b3efa5bf78d8f9f9422fbf449 200 SMART SM00116 83 131 2.6E-5 T 28-03-2018 IPR000644 CBS domain CU254_RS16200 689f8e9b3efa5bf78d8f9f9422fbf449 200 SMART SM00116 10 58 2.4E-7 T 28-03-2018 IPR000644 CBS domain CU254_RS16200 689f8e9b3efa5bf78d8f9f9422fbf449 200 Pfam PF00571 CBS domain 76 131 5.8E-9 T 28-03-2018 IPR000644 CBS domain CU254_RS16200 689f8e9b3efa5bf78d8f9f9422fbf449 200 Pfam PF00571 CBS domain 3 53 2.5E-11 T 28-03-2018 IPR000644 CBS domain CU254_RS16200 689f8e9b3efa5bf78d8f9f9422fbf449 200 SUPERFAMILY SSF54631 1 132 1.39E-28 T 28-03-2018 CU254_RS16200 689f8e9b3efa5bf78d8f9f9422fbf449 200 Gene3D G3DSA:3.10.580.10 1 180 2.4E-29 T 28-03-2018 CU254_RS02855 850a2a166ca2be498297a93354d6ccf5 363 Gene3D G3DSA:3.20.20.140 5 355 1.6E-77 T 28-03-2018 CU254_RS02855 850a2a166ca2be498297a93354d6ccf5 363 SUPERFAMILY SSF51556 4 354 7.66E-70 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS02855 850a2a166ca2be498297a93354d6ccf5 363 Hamap MF_00540 Adenosine deaminase [add]. 10 355 52.29 T 28-03-2018 IPR028893 Adenosine deaminase GO:0004000|GO:0009168 KEGG: 00230+3.5.4.4|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-74217 CU254_RS02855 850a2a166ca2be498297a93354d6ccf5 363 Pfam PF00962 Adenosine/AMP deaminase 15 353 3.7E-83 T 28-03-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 CU254_RS02855 850a2a166ca2be498297a93354d6ccf5 363 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 16 354 1.0E-74 T 28-03-2018 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 CU254_RS24220 e2c173b170a510ad673098f9720c9bd0 142 SUPERFAMILY SSF46785 13 141 5.86E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS24220 e2c173b170a510ad673098f9720c9bd0 142 Pfam PF12802 MarR family 38 93 1.8E-10 T 28-03-2018 CU254_RS24220 e2c173b170a510ad673098f9720c9bd0 142 SMART SM00347 29 129 8.2E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS24220 e2c173b170a510ad673098f9720c9bd0 142 Gene3D G3DSA:1.10.10.10 3 142 1.4E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS31970 e5140fda766a9023ea893538adc23178 246 PIRSF PIRSF015736 9 245 5.3E-59 T 28-03-2018 IPR026286 Maleate isomerase/Arylmalonate decarboxylase CU254_RS31970 e5140fda766a9023ea893538adc23178 246 Gene3D G3DSA:3.40.50.1860 119 218 8.3E-6 T 28-03-2018 CU254_RS29110 1183a1c0734de00c916c78f8e29df280 198 Gene3D G3DSA:1.10.357.10 68 197 3.3E-8 T 28-03-2018 CU254_RS29110 1183a1c0734de00c916c78f8e29df280 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 27 67 6.6E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS29110 1183a1c0734de00c916c78f8e29df280 198 Gene3D G3DSA:1.10.10.60 6 67 2.6E-9 T 28-03-2018 CU254_RS29110 1183a1c0734de00c916c78f8e29df280 198 SUPERFAMILY SSF46689 17 73 6.67E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS30735 629fbe5a5b882b703a3064ea9b51ebdb 147 Pfam PF07681 DoxX 28 107 5.0E-8 T 28-03-2018 IPR032808 DoxX family CU254_RS08435 57977ca1f6b3fb460e2eafa82f82a59d 529 SUPERFAMILY SSF51905 23 329 4.89E-32 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS08435 57977ca1f6b3fb460e2eafa82f82a59d 529 Pfam PF13450 NAD(P)-binding Rossmann-like domain 28 73 7.0E-11 T 28-03-2018 CU254_RS08435 57977ca1f6b3fb460e2eafa82f82a59d 529 Gene3D G3DSA:3.50.50.60 12 529 1.9E-27 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS34080 07aabe219b62297dff999554349fbb56 321 Gene3D G3DSA:1.10.10.10 1 85 1.2E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS34080 07aabe219b62297dff999554349fbb56 321 Gene3D G3DSA:3.40.190.10 184 267 3.2E-13 T 28-03-2018 CU254_RS34080 07aabe219b62297dff999554349fbb56 321 Gene3D G3DSA:3.40.190.10 86 183 2.0E-13 T 28-03-2018 CU254_RS34080 07aabe219b62297dff999554349fbb56 321 Pfam PF03466 LysR substrate binding domain 89 283 3.2E-20 T 28-03-2018 IPR005119 LysR, substrate-binding CU254_RS34080 07aabe219b62297dff999554349fbb56 321 SUPERFAMILY SSF46785 3 112 1.52E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS34080 07aabe219b62297dff999554349fbb56 321 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 64 1.3E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS34080 07aabe219b62297dff999554349fbb56 321 SUPERFAMILY SSF53850 89 286 7.6E-19 T 28-03-2018 CU254_RS34080 07aabe219b62297dff999554349fbb56 321 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 2.0E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS34080 07aabe219b62297dff999554349fbb56 321 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 2.0E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS34080 07aabe219b62297dff999554349fbb56 321 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 2.0E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS21055 4b9b2b76b3ab4597f960bcdd54e09307 418 Gene3D G3DSA:1.20.1250.20 204 402 3.6E-26 T 28-03-2018 CU254_RS21055 4b9b2b76b3ab4597f960bcdd54e09307 418 Gene3D G3DSA:1.20.1250.20 9 203 3.5E-37 T 28-03-2018 CU254_RS21055 4b9b2b76b3ab4597f960bcdd54e09307 418 ProSitePatterns PS00216 Sugar transport proteins signature 1. 71 87 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CU254_RS21055 4b9b2b76b3ab4597f960bcdd54e09307 418 SUPERFAMILY SSF103473 7 399 1.57E-77 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS21055 4b9b2b76b3ab4597f960bcdd54e09307 418 Pfam PF07690 Major Facilitator Superfamily 20 271 4.0E-33 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS26675 410b5e3336737636b96b01fa796d43b2 148 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 13 93 1.3E-6 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CU254_RS26675 410b5e3336737636b96b01fa796d43b2 148 Gene3D G3DSA:2.30.110.10 2 146 4.2E-16 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS26675 410b5e3336737636b96b01fa796d43b2 148 SUPERFAMILY SSF50475 13 146 3.18E-17 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS21865 ad5e9aef4a0011a11cb4e47b5f4c668a 430 SUPERFAMILY SSF51735 194 429 1.04E-50 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS21865 ad5e9aef4a0011a11cb4e47b5f4c668a 430 Gene3D G3DSA:3.40.50.720 191 430 6.9E-51 T 28-03-2018 CU254_RS21865 ad5e9aef4a0011a11cb4e47b5f4c668a 430 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 393 413 2.7E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS21865 ad5e9aef4a0011a11cb4e47b5f4c668a 430 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 337 356 2.7E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS21865 ad5e9aef4a0011a11cb4e47b5f4c668a 430 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 356 373 2.7E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS21865 ad5e9aef4a0011a11cb4e47b5f4c668a 430 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 216 2.7E-18 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS21865 ad5e9aef4a0011a11cb4e47b5f4c668a 430 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 207 428 2.4E-33 T 28-03-2018 CU254_RS10410 5674acf2a402927865a339f80fb8c233 187 Pfam PF01872 RibD C-terminal domain 6 175 2.8E-15 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CU254_RS10410 5674acf2a402927865a339f80fb8c233 187 Gene3D G3DSA:3.40.430.10 4 181 7.2E-29 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CU254_RS10410 5674acf2a402927865a339f80fb8c233 187 SUPERFAMILY SSF53597 2 181 1.27E-23 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CU254_RS33540 139d91f088c12bade5b5026a49b033a6 542 PIRSF PIRSF002741 5 529 1.9E-72 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CU254_RS33540 139d91f088c12bade5b5026a49b033a6 542 Gene3D G3DSA:3.40.190.10 182 315 3.3E-29 T 28-03-2018 CU254_RS33540 139d91f088c12bade5b5026a49b033a6 542 SUPERFAMILY SSF53850 35 534 4.21E-95 T 28-03-2018 CU254_RS33540 139d91f088c12bade5b5026a49b033a6 542 Gene3D G3DSA:3.90.76.10 59 181 2.3E-20 T 28-03-2018 CU254_RS33540 139d91f088c12bade5b5026a49b033a6 542 Gene3D G3DSA:3.10.105.10 316 512 4.0E-42 T 28-03-2018 CU254_RS33540 139d91f088c12bade5b5026a49b033a6 542 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 88 461 1.8E-59 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CU254_RS18930 4cc189dad917b75fdf772ebff56eac8f 324 Pfam PF07859 alpha/beta hydrolase fold 87 295 6.4E-62 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CU254_RS18930 4cc189dad917b75fdf772ebff56eac8f 324 Gene3D G3DSA:3.40.50.1820 6 324 2.4E-57 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS18930 4cc189dad917b75fdf772ebff56eac8f 324 SUPERFAMILY SSF53474 28 321 1.4E-64 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS40530 9efc52dd6cea28eefd37278cbcfecd56 292 Gene3D G3DSA:1.10.3720.10 33 281 2.5E-25 T 28-03-2018 CU254_RS40530 9efc52dd6cea28eefd37278cbcfecd56 292 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 107 276 1.5E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS40530 9efc52dd6cea28eefd37278cbcfecd56 292 SUPERFAMILY SSF161098 83 268 1.96E-30 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS33530 7836d79fea98166140346ddc3a275ca3 318 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 126 317 1.2E-27 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS33530 7836d79fea98166140346ddc3a275ca3 318 SUPERFAMILY SSF161098 105 300 3.53E-23 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS33530 7836d79fea98166140346ddc3a275ca3 318 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 33 79 1.3E-10 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CU254_RS33530 7836d79fea98166140346ddc3a275ca3 318 Gene3D G3DSA:1.10.3720.10 37 307 6.7E-40 T 28-03-2018 CU254_RS28690 460236bf4f7023c78338e8d5e253e670 535 ProDom PD141294 TRANSMEMBRANE MEMBRANE PROTEIN GTRIV-SF YFDI PREDICTED 310 393 5.0E-7 T 28-03-2018 CU254_RS28690 460236bf4f7023c78338e8d5e253e670 535 ProDom PD141294 TRANSMEMBRANE MEMBRANE PROTEIN GTRIV-SF YFDI PREDICTED 67 216 0.004 T 28-03-2018 CU254_RS19725 50a21592e7b5cd4772cc9f3cdaf04bf8 298 Gene3D G3DSA:1.10.3720.10 25 284 3.1E-34 T 28-03-2018 CU254_RS19725 50a21592e7b5cd4772cc9f3cdaf04bf8 298 SUPERFAMILY SSF161098 97 275 8.63E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS19725 50a21592e7b5cd4772cc9f3cdaf04bf8 298 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 111 293 2.9E-27 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS26045 6a6d498af66a3b75715d44679eb5d288 423 Pfam PF06508 Queuosine biosynthesis protein QueC 247 324 9.0E-8 T 28-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 CU254_RS26045 6a6d498af66a3b75715d44679eb5d288 423 SUPERFAMILY SSF52402 118 326 4.83E-12 T 28-03-2018 CU254_RS26045 6a6d498af66a3b75715d44679eb5d288 423 Gene3D G3DSA:3.40.50.620 118 337 8.7E-11 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS37550 58d2a31b09a11238fef19917c03ee76d 277 SUPERFAMILY SSF53474 61 271 2.66E-16 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS37550 58d2a31b09a11238fef19917c03ee76d 277 Pfam PF12697 Alpha/beta hydrolase family 62 267 9.0E-9 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS37550 58d2a31b09a11238fef19917c03ee76d 277 Gene3D G3DSA:3.40.50.1820 4 271 7.9E-14 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS22435 835ef216293dcc645053d86e0bcb22cd 166 Pfam PF01316 Arginine repressor, DNA binding domain 5 72 4.7E-22 T 28-03-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 CU254_RS22435 835ef216293dcc645053d86e0bcb22cd 166 TIGRFAM TIGR01529 argR_whole: arginine repressor 7 156 1.0E-44 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CU254_RS22435 835ef216293dcc645053d86e0bcb22cd 166 Gene3D G3DSA:3.30.1360.40 82 153 1.7E-29 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CU254_RS22435 835ef216293dcc645053d86e0bcb22cd 166 SUPERFAMILY SSF55252 88 154 1.06E-16 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CU254_RS22435 835ef216293dcc645053d86e0bcb22cd 166 Pfam PF02863 Arginine repressor, C-terminal domain 88 154 7.8E-24 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CU254_RS22435 835ef216293dcc645053d86e0bcb22cd 166 Hamap MF_00173 Arginine repressor [argR]. 1 160 60.19 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CU254_RS22435 835ef216293dcc645053d86e0bcb22cd 166 Gene3D G3DSA:1.10.10.10 5 69 4.8E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS22435 835ef216293dcc645053d86e0bcb22cd 166 PRINTS PR01467 Bacterial arginine repressor signature 126 141 1.4E-25 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CU254_RS22435 835ef216293dcc645053d86e0bcb22cd 166 PRINTS PR01467 Bacterial arginine repressor signature 96 109 1.4E-25 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CU254_RS22435 835ef216293dcc645053d86e0bcb22cd 166 PRINTS PR01467 Bacterial arginine repressor signature 39 54 1.4E-25 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CU254_RS22435 835ef216293dcc645053d86e0bcb22cd 166 PRINTS PR01467 Bacterial arginine repressor signature 23 36 1.4E-25 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CU254_RS22435 835ef216293dcc645053d86e0bcb22cd 166 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 96 151 1.0E-18 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CU254_RS22435 835ef216293dcc645053d86e0bcb22cd 166 SUPERFAMILY SSF46785 4 72 2.38E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS40635 20bad4a49fbe22a5a1f18e959a54733f 659 Pfam PF13193 AMP-binding enzyme C-terminal domain 568 620 9.9E-6 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS40635 20bad4a49fbe22a5a1f18e959a54733f 659 Gene3D G3DSA:3.40.50.980 103 280 1.6E-33 T 28-03-2018 CU254_RS40635 20bad4a49fbe22a5a1f18e959a54733f 659 Pfam PF00501 AMP-binding enzyme 107 532 5.4E-52 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS40635 20bad4a49fbe22a5a1f18e959a54733f 659 TIGRFAM TIGR01217 ac_ac_CoA_syn: acetoacetate-CoA ligase 8 657 2.3E-241 T 28-03-2018 IPR005914 Acetoacetyl-CoA synthase GO:0006629|GO:0030729 KEGG: 00280+6.2.1.16|KEGG: 00650+6.2.1.16|Reactome: R-HSA-77111 CU254_RS40635 20bad4a49fbe22a5a1f18e959a54733f 659 Gene3D G3DSA:2.30.38.10 450 527 4.9E-4 T 28-03-2018 CU254_RS40635 20bad4a49fbe22a5a1f18e959a54733f 659 Gene3D G3DSA:3.30.300.30 528 636 6.5E-13 T 28-03-2018 CU254_RS40635 20bad4a49fbe22a5a1f18e959a54733f 659 Gene3D G3DSA:3.40.50.980 281 441 1.4E-28 T 28-03-2018 CU254_RS40635 20bad4a49fbe22a5a1f18e959a54733f 659 ProSitePatterns PS00455 Putative AMP-binding domain signature. 275 286 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS40635 20bad4a49fbe22a5a1f18e959a54733f 659 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 42 95 1.5E-12 T 28-03-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 CU254_RS40635 20bad4a49fbe22a5a1f18e959a54733f 659 SUPERFAMILY SSF56801 41 634 1.02E-123 T 28-03-2018 CU254_RS07335 67f26f8f41a7bf2aa4b0e7ee612cad61 60 SUPERFAMILY SSF57829 2 58 4.52E-16 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CU254_RS07335 67f26f8f41a7bf2aa4b0e7ee612cad61 60 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 58 4.7E-19 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS07335 67f26f8f41a7bf2aa4b0e7ee612cad61 60 Pfam PF01783 Ribosomal L32p protein family 2 58 6.3E-22 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS07335 67f26f8f41a7bf2aa4b0e7ee612cad61 60 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 2 57 16.228 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS32560 203ef05f22528f9b862c2487c59cb962 410 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 4 390 9.5E-66 T 28-03-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CU254_RS32560 203ef05f22528f9b862c2487c59cb962 410 Gene3D G3DSA:2.60.120.10 5 162 4.3E-47 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS32560 203ef05f22528f9b862c2487c59cb962 410 Gene3D G3DSA:2.60.120.10 303 407 1.5E-20 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS32560 203ef05f22528f9b862c2487c59cb962 410 Pfam PF01238 Phosphomannose isomerase type I 4 366 6.0E-60 T 28-03-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CU254_RS32560 203ef05f22528f9b862c2487c59cb962 410 PRINTS PR00714 Phosphomannose isomerase type I signature 32 47 9.0E-58 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CU254_RS32560 203ef05f22528f9b862c2487c59cb962 410 PRINTS PR00714 Phosphomannose isomerase type I signature 4 22 9.0E-58 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CU254_RS32560 203ef05f22528f9b862c2487c59cb962 410 PRINTS PR00714 Phosphomannose isomerase type I signature 245 264 9.0E-58 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CU254_RS32560 203ef05f22528f9b862c2487c59cb962 410 PRINTS PR00714 Phosphomannose isomerase type I signature 229 244 9.0E-58 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CU254_RS32560 203ef05f22528f9b862c2487c59cb962 410 PRINTS PR00714 Phosphomannose isomerase type I signature 82 103 9.0E-58 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CU254_RS32560 203ef05f22528f9b862c2487c59cb962 410 PRINTS PR00714 Phosphomannose isomerase type I signature 127 150 9.0E-58 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CU254_RS32560 203ef05f22528f9b862c2487c59cb962 410 PRINTS PR00714 Phosphomannose isomerase type I signature 264 283 9.0E-58 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CU254_RS32560 203ef05f22528f9b862c2487c59cb962 410 PRINTS PR00714 Phosphomannose isomerase type I signature 283 302 9.0E-58 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CU254_RS32560 203ef05f22528f9b862c2487c59cb962 410 SUPERFAMILY SSF51182 3 386 1.48E-92 T 28-03-2018 IPR011051 RmlC-like cupin domain CU254_RS32560 203ef05f22528f9b862c2487c59cb962 410 PIRSF PIRSF001480 1 408 9.5E-94 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CU254_RS32560 203ef05f22528f9b862c2487c59cb962 410 Gene3D G3DSA:1.10.441.10 163 271 4.3E-26 T 28-03-2018 CU254_RS02590 bb8cfb1c6282ec0ca7f1d34fee5c4129 389 Gene3D G3DSA:3.30.1490.20 21 87 3.1E-26 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CU254_RS02590 bb8cfb1c6282ec0ca7f1d34fee5c4129 389 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 249 273 - T 28-03-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CU254_RS02590 bb8cfb1c6282ec0ca7f1d34fee5c4129 389 SUPERFAMILY SSF56059 3 228 4.77E-67 T 28-03-2018 CU254_RS02590 bb8cfb1c6282ec0ca7f1d34fee5c4129 389 Gene3D G3DSA:3.40.50.261 232 385 1.2E-36 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CU254_RS02590 bb8cfb1c6282ec0ca7f1d34fee5c4129 389 Gene3D G3DSA:3.30.470.20 88 231 1.9E-46 T 28-03-2018 CU254_RS02590 bb8cfb1c6282ec0ca7f1d34fee5c4129 389 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 386 37.87 T 28-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CU254_RS02590 bb8cfb1c6282ec0ca7f1d34fee5c4129 389 Pfam PF08442 ATP-grasp domain 2 194 4.2E-69 T 28-03-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CU254_RS02590 bb8cfb1c6282ec0ca7f1d34fee5c4129 389 PIRSF PIRSF001554 1 388 2.6E-137 T 28-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CU254_RS02590 bb8cfb1c6282ec0ca7f1d34fee5c4129 389 Pfam PF00549 CoA-ligase 256 378 4.2E-12 T 28-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CU254_RS02590 bb8cfb1c6282ec0ca7f1d34fee5c4129 389 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 2 385 1.7E-123 T 28-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CU254_RS02590 bb8cfb1c6282ec0ca7f1d34fee5c4129 389 SUPERFAMILY SSF52210 231 385 5.36E-41 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CU254_RS35915 c80932a892bb1acefaa669880c743e20 197 Pfam PF16708 Lipoprotein confined to pathogenic Mycobacterium 41 183 1.3E-22 T 28-03-2018 IPR032018 Putative lipoprotein, pathogenic bacteria CU254_RS22315 b6f744023749663b73e082c5e960b199 566 Hamap MF_01227 CTP synthase [pyrG]. 8 549 50.002 T 28-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CU254_RS22315 b6f744023749663b73e082c5e960b199 566 Gene3D G3DSA:3.40.50.300 2 296 1.3E-127 T 28-03-2018 CU254_RS22315 b6f744023749663b73e082c5e960b199 566 Pfam PF00117 Glutamine amidotransferase class-I 312 544 5.0E-49 T 28-03-2018 IPR017926 Glutamine amidotransferase CU254_RS22315 b6f744023749663b73e082c5e960b199 566 TIGRFAM TIGR00337 PyrG: CTP synthase 7 544 3.1E-231 T 28-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CU254_RS22315 b6f744023749663b73e082c5e960b199 566 SUPERFAMILY SSF52540 8 277 4.5E-118 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS22315 b6f744023749663b73e082c5e960b199 566 Pfam PF06418 CTP synthase N-terminus 9 277 3.2E-122 T 28-03-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CU254_RS22315 b6f744023749663b73e082c5e960b199 566 SUPERFAMILY SSF52317 301 548 3.67E-74 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS22315 b6f744023749663b73e082c5e960b199 566 Gene3D G3DSA:3.40.50.880 297 551 4.0E-68 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS09625 6ecfe1a95a4fbdd1181183e7a00ef132 71 Pfam PF12728 Helix-turn-helix domain 16 63 2.2E-7 T 28-03-2018 CU254_RS09625 6ecfe1a95a4fbdd1181183e7a00ef132 71 SUPERFAMILY SSF46955 15 62 8.55E-8 T 28-03-2018 IPR009061 Putative DNA-binding domain CU254_RS09625 6ecfe1a95a4fbdd1181183e7a00ef132 71 Gene3D G3DSA:1.10.10.10 17 70 4.4E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS07370 949fbbc1fd0d266012af87a4cc5a73eb 237 Pfam PF07722 Peptidase C26 9 217 3.4E-61 T 28-03-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 CU254_RS07370 949fbbc1fd0d266012af87a4cc5a73eb 237 Gene3D G3DSA:3.40.50.880 5 237 3.0E-45 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS07370 949fbbc1fd0d266012af87a4cc5a73eb 237 SUPERFAMILY SSF52317 9 234 8.41E-37 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS38745 9108eb6ff0b62c2d6f582498a3655bf7 608 Gene3D G3DSA:3.40.50.300 8 602 1.3E-30 T 28-03-2018 CU254_RS38745 9108eb6ff0b62c2d6f582498a3655bf7 608 SUPERFAMILY SSF52540 37 275 1.04E-27 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS38745 9108eb6ff0b62c2d6f582498a3655bf7 608 Pfam PF00350 Dynamin family 45 202 3.6E-15 T 28-03-2018 IPR022812 Dynamin superfamily CU254_RS10870 ffc87e1c56b850ff1f683b3f8dfc370e 102 Pfam PF13834 Domain of unknown function (DUF4193) 1 102 4.3E-42 T 28-03-2018 IPR025242 Protein of unknown function DUF4193 CU254_RS00945 fc608d679a7beb33c9decb005170bb95 134 SUPERFAMILY SSF55961 7 134 2.03E-17 T 28-03-2018 CU254_RS00945 fc608d679a7beb33c9decb005170bb95 134 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 22 131 4.2E-7 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CU254_RS00945 fc608d679a7beb33c9decb005170bb95 134 Gene3D G3DSA:3.30.530.20 11 134 3.3E-12 T 28-03-2018 IPR023393 START-like domain CU254_RS07965 16af0d5ebdd1e4a3594fbd25732c0d28 147 SUPERFAMILY SSF54565 2 94 1.19E-31 T 28-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS07965 16af0d5ebdd1e4a3594fbd25732c0d28 147 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 79 1.5E-29 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS07965 16af0d5ebdd1e4a3594fbd25732c0d28 147 Pfam PF00886 Ribosomal protein S16 9 67 2.4E-22 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS07965 16af0d5ebdd1e4a3594fbd25732c0d28 147 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 77 22.546 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS07965 16af0d5ebdd1e4a3594fbd25732c0d28 147 Gene3D G3DSA:3.30.1320.10 2 84 3.6E-29 T 28-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS13500 ed122f2555de1e2ab8e21a3c8eea4778 389 Gene3D G3DSA:1.20.1250.20 10 206 3.9E-20 T 28-03-2018 CU254_RS13500 ed122f2555de1e2ab8e21a3c8eea4778 389 SUPERFAMILY SSF103473 9 388 4.71E-44 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS13500 ed122f2555de1e2ab8e21a3c8eea4778 389 Pfam PF07690 Major Facilitator Superfamily 19 209 1.1E-11 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS13500 ed122f2555de1e2ab8e21a3c8eea4778 389 Gene3D G3DSA:1.20.1250.20 207 388 4.1E-15 T 28-03-2018 CU254_RS01380 c704ac98adbf5b0ee55e587b5cc7d6c9 180 SUPERFAMILY SSF54862 29 145 1.42E-24 T 28-03-2018 CU254_RS01380 c704ac98adbf5b0ee55e587b5cc7d6c9 180 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 101 112 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CU254_RS01380 c704ac98adbf5b0ee55e587b5cc7d6c9 180 Gene3D G3DSA:3.30.70.20 103 179 2.7E-7 T 28-03-2018 CU254_RS01380 c704ac98adbf5b0ee55e587b5cc7d6c9 180 Pfam PF12838 4Fe-4S dicluster domain 55 113 1.9E-11 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CU254_RS01380 c704ac98adbf5b0ee55e587b5cc7d6c9 180 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 12 139 2.3E-38 T 28-03-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS01380 c704ac98adbf5b0ee55e587b5cc7d6c9 180 Gene3D G3DSA:3.30.70.20 46 102 1.3E-15 T 28-03-2018 CU254_RS01380 c704ac98adbf5b0ee55e587b5cc7d6c9 180 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 3 149 26.73 T 28-03-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS36810 e2b4311f0ae4c934d50c995f5e9943cc 151 SUPERFAMILY SSF55298 2 150 6.91E-54 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CU254_RS36810 e2b4311f0ae4c934d50c995f5e9943cc 151 Gene3D G3DSA:3.30.1330.40 1 151 9.2E-32 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CU254_RS36810 e2b4311f0ae4c934d50c995f5e9943cc 151 Pfam PF14588 YjgF/chorismate_mutase-like, putative endoribonuclease 6 150 2.4E-30 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CU254_RS08395 62c19017e7fb33d95bcff150b0723448 464 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 36 46 - T 28-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CU254_RS08395 62c19017e7fb33d95bcff150b0723448 464 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 348 456 7.5E-27 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CU254_RS08395 62c19017e7fb33d95bcff150b0723448 464 TIGRFAM TIGR03452 mycothione_red: mycothione reductase 3 461 6.9E-201 T 28-03-2018 IPR017817 Mycothione reductase MetaCyc: PWY-6421 CU254_RS08395 62c19017e7fb33d95bcff150b0723448 464 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 263 279 8.5E-28 T 28-03-2018 CU254_RS08395 62c19017e7fb33d95bcff150b0723448 464 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 8.5E-28 T 28-03-2018 CU254_RS08395 62c19017e7fb33d95bcff150b0723448 464 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 292 314 8.5E-28 T 28-03-2018 CU254_RS08395 62c19017e7fb33d95bcff150b0723448 464 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 138 156 8.5E-28 T 28-03-2018 CU254_RS08395 62c19017e7fb33d95bcff150b0723448 464 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 177 195 8.5E-28 T 28-03-2018 CU254_RS08395 62c19017e7fb33d95bcff150b0723448 464 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 326 1.7E-50 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS08395 62c19017e7fb33d95bcff150b0723448 464 Gene3D G3DSA:3.30.390.30 336 461 3.0E-34 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CU254_RS08395 62c19017e7fb33d95bcff150b0723448 464 SUPERFAMILY SSF51905 3 369 1.99E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS08395 62c19017e7fb33d95bcff150b0723448 464 PIRSF PIRSF000350 1 444 1.7E-85 T 28-03-2018 CU254_RS08395 62c19017e7fb33d95bcff150b0723448 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 264 278 2.2E-43 T 28-03-2018 CU254_RS08395 62c19017e7fb33d95bcff150b0723448 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 409 424 2.2E-43 T 28-03-2018 CU254_RS08395 62c19017e7fb33d95bcff150b0723448 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 307 314 2.2E-43 T 28-03-2018 CU254_RS08395 62c19017e7fb33d95bcff150b0723448 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 2.2E-43 T 28-03-2018 CU254_RS08395 62c19017e7fb33d95bcff150b0723448 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 141 150 2.2E-43 T 28-03-2018 CU254_RS08395 62c19017e7fb33d95bcff150b0723448 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 177 202 2.2E-43 T 28-03-2018 CU254_RS08395 62c19017e7fb33d95bcff150b0723448 464 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 344 365 2.2E-43 T 28-03-2018 CU254_RS08395 62c19017e7fb33d95bcff150b0723448 464 Gene3D G3DSA:3.50.50.60 2 169 2.0E-20 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS08395 62c19017e7fb33d95bcff150b0723448 464 Gene3D G3DSA:3.40.50.720 170 335 3.4E-31 T 28-03-2018 CU254_RS08395 62c19017e7fb33d95bcff150b0723448 464 SUPERFAMILY SSF55424 345 459 4.47E-31 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CU254_RS20350 1622b23d01b93829c8cb637810f07b96 471 Gene3D G3DSA:3.90.1150.10 277 395 3.6E-19 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS20350 1622b23d01b93829c8cb637810f07b96 471 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 38 330 1.2E-19 T 28-03-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 CU254_RS20350 1622b23d01b93829c8cb637810f07b96 471 Gene3D G3DSA:3.40.640.10 32 276 7.1E-39 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS20350 1622b23d01b93829c8cb637810f07b96 471 SUPERFAMILY SSF53383 3 385 1.09E-90 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS33970 f2aa052829177a7d5620b85dd48ff10d 106 Gene3D G3DSA:1.10.10.10 4 94 1.6E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS33970 f2aa052829177a7d5620b85dd48ff10d 106 Pfam PF12840 Helix-turn-helix domain 18 73 3.2E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS33970 f2aa052829177a7d5620b85dd48ff10d 106 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 20 35 1.1E-5 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS33970 f2aa052829177a7d5620b85dd48ff10d 106 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 54 69 1.1E-5 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS33970 f2aa052829177a7d5620b85dd48ff10d 106 SMART SM00418 18 98 7.4E-5 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS33970 f2aa052829177a7d5620b85dd48ff10d 106 SUPERFAMILY SSF46785 14 99 7.17E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS20305 b2066544f5e0c67e1800d03b6abbef71 55 ProSitePatterns PS00582 Ribosomal protein L33 signature. 23 42 - T 28-03-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS20305 b2066544f5e0c67e1800d03b6abbef71 55 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 1 55 9.1E-23 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS20305 b2066544f5e0c67e1800d03b6abbef71 55 SUPERFAMILY SSF57829 4 55 6.71E-18 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CU254_RS20305 b2066544f5e0c67e1800d03b6abbef71 55 Pfam PF00471 Ribosomal protein L33 10 55 1.7E-17 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS20305 b2066544f5e0c67e1800d03b6abbef71 55 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 7 55 14.39 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS05215 534ed13ad0c38633ce6cbfeccef85408 344 Gene3D G3DSA:3.40.50.2300 177 322 1.3E-42 T 28-03-2018 CU254_RS05215 534ed13ad0c38633ce6cbfeccef85408 344 Gene3D G3DSA:1.10.260.40 1 54 9.3E-23 T 28-03-2018 CU254_RS05215 534ed13ad0c38633ce6cbfeccef85408 344 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 28-03-2018 CU254_RS05215 534ed13ad0c38633ce6cbfeccef85408 344 Gene3D G3DSA:3.40.50.2300 55 176 7.9E-25 T 28-03-2018 CU254_RS05215 534ed13ad0c38633ce6cbfeccef85408 344 SMART SM00354 2 72 2.7E-26 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CU254_RS05215 534ed13ad0c38633ce6cbfeccef85408 344 SUPERFAMILY SSF53822 63 336 5.5E-62 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CU254_RS05215 534ed13ad0c38633ce6cbfeccef85408 344 Pfam PF13377 Periplasmic binding protein-like domain 171 334 9.1E-38 T 28-03-2018 CU254_RS05215 534ed13ad0c38633ce6cbfeccef85408 344 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 5.3E-17 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CU254_RS05215 534ed13ad0c38633ce6cbfeccef85408 344 SUPERFAMILY SSF47413 3 60 6.38E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS33270 9acb6dc19a81b50df0f1309fc62cb4ba 249 SUPERFAMILY SSF88713 17 227 2.22E-53 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CU254_RS33270 9acb6dc19a81b50df0f1309fc62cb4ba 249 Pfam PF01522 Polysaccharide deacetylase 32 151 1.1E-30 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CU254_RS33270 9acb6dc19a81b50df0f1309fc62cb4ba 249 Gene3D G3DSA:3.20.20.370 20 232 4.1E-45 T 28-03-2018 CU254_RS22665 0293f822e82dda1b03a622b24285294a 116 SUPERFAMILY SSF159888 5 111 3.79E-11 T 28-03-2018 CU254_RS22665 0293f822e82dda1b03a622b24285294a 116 Pfam PF08818 Domain of unknown function (DU1801) 23 107 2.5E-9 T 28-03-2018 IPR014922 Domain of unknown function DUF1801 CU254_RS29990 a8f6d45e73be4d312d8b4e6290f22f4f 206 Pfam PF01872 RibD C-terminal domain 3 191 3.9E-27 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CU254_RS29990 a8f6d45e73be4d312d8b4e6290f22f4f 206 SUPERFAMILY SSF53597 1 192 3.14E-29 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CU254_RS29990 a8f6d45e73be4d312d8b4e6290f22f4f 206 Gene3D G3DSA:3.40.430.10 1 194 1.6E-34 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CU254_RS13480 80929f81d0e18ddced9f779377786c5e 179 SUPERFAMILY SSF55729 14 158 8.75E-19 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS13480 80929f81d0e18ddced9f779377786c5e 179 Pfam PF13508 Acetyltransferase (GNAT) domain 58 147 2.1E-9 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS13480 80929f81d0e18ddced9f779377786c5e 179 Gene3D G3DSA:3.40.630.30 2 155 2.4E-19 T 28-03-2018 CU254_RS42180 51fed73d449a48d8cbf4f5cfeae7c117 272 Gene3D G3DSA:3.40.50.1820 1 262 6.8E-6 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS42180 51fed73d449a48d8cbf4f5cfeae7c117 272 SUPERFAMILY SSF53474 192 246 6.98E-8 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS42180 51fed73d449a48d8cbf4f5cfeae7c117 272 SUPERFAMILY SSF53474 26 164 6.98E-8 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS39170 1eb86f0a94e7abc7bd94a941bace70ba 107 Pfam PF00085 Thioredoxin 5 104 4.4E-34 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 CU254_RS39170 1eb86f0a94e7abc7bd94a941bace70ba 107 SUPERFAMILY SSF52833 3 107 1.18E-38 T 28-03-2018 IPR012336 Thioredoxin-like fold CU254_RS39170 1eb86f0a94e7abc7bd94a941bace70ba 107 ProSitePatterns PS00194 Thioredoxin family active site. 24 42 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CU254_RS39170 1eb86f0a94e7abc7bd94a941bace70ba 107 PRINTS PR00421 Thioredoxin family signature 31 40 1.7E-8 T 28-03-2018 CU254_RS39170 1eb86f0a94e7abc7bd94a941bace70ba 107 PRINTS PR00421 Thioredoxin family signature 23 31 1.7E-8 T 28-03-2018 CU254_RS39170 1eb86f0a94e7abc7bd94a941bace70ba 107 PRINTS PR00421 Thioredoxin family signature 71 82 1.7E-8 T 28-03-2018 CU254_RS39170 1eb86f0a94e7abc7bd94a941bace70ba 107 TIGRFAM TIGR01068 thioredoxin: thioredoxin 8 104 6.6E-40 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CU254_RS39170 1eb86f0a94e7abc7bd94a941bace70ba 107 Gene3D G3DSA:3.40.30.10 2 107 2.5E-36 T 28-03-2018 CU254_RS39170 1eb86f0a94e7abc7bd94a941bace70ba 107 PIRSF PIRSF000077 1 107 2.0E-44 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CU254_RS21310 389c25b5e5ab515830547d221ed036ab 274 Gene3D G3DSA:2.60.200.20 16 150 2.3E-5 T 28-03-2018 CU254_RS21310 389c25b5e5ab515830547d221ed036ab 274 SUPERFAMILY SSF49879 19 112 7.15E-7 T 28-03-2018 IPR008984 SMAD/FHA domain GO:0005515 CU254_RS18335 783147ff4079c1d89c3c1d4d8d8f7b04 380 Pfam PF00557 Metallopeptidase family M24 159 362 2.4E-59 T 28-03-2018 IPR000994 Peptidase M24 CU254_RS18335 783147ff4079c1d89c3c1d4d8d8f7b04 380 SUPERFAMILY SSF55920 150 378 5.63E-71 T 28-03-2018 IPR000994 Peptidase M24 CU254_RS18335 783147ff4079c1d89c3c1d4d8d8f7b04 380 SUPERFAMILY SSF53092 12 149 2.09E-23 T 28-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal CU254_RS18335 783147ff4079c1d89c3c1d4d8d8f7b04 380 Pfam PF01321 Creatinase/Prolidase N-terminal domain 19 151 7.6E-14 T 28-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 CU254_RS18335 783147ff4079c1d89c3c1d4d8d8f7b04 380 Gene3D G3DSA:3.90.230.10 136 380 2.5E-69 T 28-03-2018 CU254_RS18335 783147ff4079c1d89c3c1d4d8d8f7b04 380 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 308 320 - T 28-03-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site CU254_RS18335 783147ff4079c1d89c3c1d4d8d8f7b04 380 Gene3D G3DSA:3.40.350.10 3 135 1.6E-20 T 28-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CU254_RS20045 4858bccc92960f675581a48433418da5 313 Gene3D G3DSA:1.10.3720.10 21 299 4.9E-47 T 28-03-2018 CU254_RS20045 4858bccc92960f675581a48433418da5 313 SUPERFAMILY SSF161098 103 291 4.97E-26 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS20045 4858bccc92960f675581a48433418da5 313 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 21 67 6.9E-6 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CU254_RS20045 4858bccc92960f675581a48433418da5 313 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 124 309 4.8E-31 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS09360 390e90571821c67d30434d94b2ead4d9 378 Gene3D G3DSA:3.20.20.140 114 378 2.5E-60 T 28-03-2018 CU254_RS09360 390e90571821c67d30434d94b2ead4d9 378 Pfam PF04909 Amidohydrolase 140 375 2.1E-6 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CU254_RS09360 390e90571821c67d30434d94b2ead4d9 378 SUPERFAMILY SSF51556 66 175 2.17E-8 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS09360 390e90571821c67d30434d94b2ead4d9 378 SUPERFAMILY SSF51556 203 375 2.17E-8 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS09360 390e90571821c67d30434d94b2ead4d9 378 SUPERFAMILY SSF51556 12 34 2.17E-8 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS23570 3860c629c20cde756acc3c59ab9911cd 205 TIGRFAM TIGR03914 UDG_fam_dom: uracil-DNA glycosylase family domain 12 203 5.0E-77 T 28-03-2018 IPR005273 Uracil-DNA glycosylase family 4 CU254_RS23570 3860c629c20cde756acc3c59ab9911cd 205 Gene3D G3DSA:3.40.470.10 15 205 4.8E-54 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CU254_RS23570 3860c629c20cde756acc3c59ab9911cd 205 SMART SM00987 41 203 1.0E-33 T 28-03-2018 CU254_RS23570 3860c629c20cde756acc3c59ab9911cd 205 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 27 195 4.6E-39 T 28-03-2018 IPR005273 Uracil-DNA glycosylase family 4 CU254_RS23570 3860c629c20cde756acc3c59ab9911cd 205 SMART SM00986 41 203 1.0E-33 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CU254_RS23570 3860c629c20cde756acc3c59ab9911cd 205 Pfam PF03167 Uracil DNA glycosylase superfamily 41 198 1.3E-36 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CU254_RS23570 3860c629c20cde756acc3c59ab9911cd 205 SUPERFAMILY SSF52141 17 202 1.21E-48 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CU254_RS33110 1da60781f504298d541018cc64de063d 310 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 76 306 1.4E-13 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS33110 1da60781f504298d541018cc64de063d 310 Gene3D G3DSA:1.20.58.370 13 54 9.4E-6 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain CU254_RS33110 1da60781f504298d541018cc64de063d 310 SUPERFAMILY SSF161098 65 297 7.72E-58 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS33110 1da60781f504298d541018cc64de063d 310 Gene3D G3DSA:1.10.3720.10 72 308 3.9E-44 T 28-03-2018 CU254_RS19735 f68b835057f879b29a86061a0a76f654 366 Pfam PF00144 Beta-lactamase 20 356 9.3E-56 T 28-03-2018 IPR001466 Beta-lactamase-related CU254_RS19735 f68b835057f879b29a86061a0a76f654 366 Gene3D G3DSA:3.40.710.10 1 366 2.8E-68 T 28-03-2018 CU254_RS19735 f68b835057f879b29a86061a0a76f654 366 SUPERFAMILY SSF56601 10 363 3.6E-58 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CU254_RS17740 31026abe8681f347e94fd1d4bcfb1c1c 209 SUPERFAMILY SSF52833 1 205 5.59E-44 T 28-03-2018 IPR012336 Thioredoxin-like fold CU254_RS17740 31026abe8681f347e94fd1d4bcfb1c1c 209 Gene3D G3DSA:3.40.30.10 1 209 6.8E-54 T 28-03-2018 CU254_RS17740 31026abe8681f347e94fd1d4bcfb1c1c 209 Pfam PF01323 DSBA-like thioredoxin domain 2 199 1.4E-45 T 28-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 CU254_RS02600 8ecc92b9154b5e06b363aed83e24eb7b 245 Pfam PF17270 Family of unknown function (DUF5336) 8 162 5.8E-40 T 28-03-2018 IPR035166 Protein of unknown function DUF5336 CU254_RS13990 1d426999d0d19864bacc198cab7452be 223 Pfam PF07729 FCD domain 94 216 7.8E-20 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS13990 1d426999d0d19864bacc198cab7452be 223 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 73 2.7E-18 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS13990 1d426999d0d19864bacc198cab7452be 223 SMART SM00895 93 217 2.0E-17 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS13990 1d426999d0d19864bacc198cab7452be 223 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 2.0E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS13990 1d426999d0d19864bacc198cab7452be 223 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 2.0E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS13990 1d426999d0d19864bacc198cab7452be 223 Gene3D G3DSA:1.20.120.530 75 223 4.7E-29 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS13990 1d426999d0d19864bacc198cab7452be 223 SMART SM00345 14 73 2.7E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS13990 1d426999d0d19864bacc198cab7452be 223 Gene3D G3DSA:1.10.10.10 4 74 7.5E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS13990 1d426999d0d19864bacc198cab7452be 223 SUPERFAMILY SSF48008 94 222 4.71E-22 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS13990 1d426999d0d19864bacc198cab7452be 223 SUPERFAMILY SSF46785 1 77 7.9E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS24005 29d1f280c14f3a20a9cbfc02da91a8ee 257 Gene3D G3DSA:3.40.50.720 1 251 5.9E-44 T 28-03-2018 CU254_RS24005 29d1f280c14f3a20a9cbfc02da91a8ee 257 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 148 247 3.1E-17 T 28-03-2018 CU254_RS24005 29d1f280c14f3a20a9cbfc02da91a8ee 257 SUPERFAMILY SSF51735 3 250 1.94E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS24005 29d1f280c14f3a20a9cbfc02da91a8ee 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.8E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS24005 29d1f280c14f3a20a9cbfc02da91a8ee 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.8E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS24005 29d1f280c14f3a20a9cbfc02da91a8ee 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 61 72 1.8E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS24005 29d1f280c14f3a20a9cbfc02da91a8ee 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 98 114 1.8E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS24005 29d1f280c14f3a20a9cbfc02da91a8ee 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 1.8E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS24005 29d1f280c14f3a20a9cbfc02da91a8ee 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 1.8E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS24005 29d1f280c14f3a20a9cbfc02da91a8ee 257 Pfam PF00106 short chain dehydrogenase 4 118 3.2E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS10275 82ecc3bc6defb72c2e2e99681486fd54 110 SMART SM00418 8 86 2.1E-15 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS10275 82ecc3bc6defb72c2e2e99681486fd54 110 SUPERFAMILY SSF46785 1 101 1.64E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS10275 82ecc3bc6defb72c2e2e99681486fd54 110 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 42 57 8.4E-8 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS10275 82ecc3bc6defb72c2e2e99681486fd54 110 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 8.4E-8 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS10275 82ecc3bc6defb72c2e2e99681486fd54 110 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 29 40 8.4E-8 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS10275 82ecc3bc6defb72c2e2e99681486fd54 110 Gene3D G3DSA:1.10.10.10 1 109 8.9E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS10275 82ecc3bc6defb72c2e2e99681486fd54 110 Pfam PF12840 Helix-turn-helix domain 9 64 3.8E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS38110 640be7fb969fa4ce8994fc11096d5598 141 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 6 85 1.5E-9 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CU254_RS38110 640be7fb969fa4ce8994fc11096d5598 141 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 9 138 5.7E-37 T 28-03-2018 IPR019920 F420-binding domain, putative CU254_RS38110 640be7fb969fa4ce8994fc11096d5598 141 SUPERFAMILY SSF50475 6 138 1.65E-31 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS38110 640be7fb969fa4ce8994fc11096d5598 141 Gene3D G3DSA:2.30.110.10 1 141 9.3E-23 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS27795 1b5632743253994e72d12d63d684f67d 248 SUPERFAMILY SSF46785 18 79 7.04E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS27795 1b5632743253994e72d12d63d684f67d 248 Gene3D G3DSA:3.30.450.40 89 247 2.9E-17 T 28-03-2018 IPR029016 GAF domain-like CU254_RS27795 1b5632743253994e72d12d63d684f67d 248 SUPERFAMILY SSF55781 91 244 6.08E-16 T 28-03-2018 IPR029016 GAF domain-like CU254_RS27795 1b5632743253994e72d12d63d684f67d 248 Pfam PF09339 IclR helix-turn-helix domain 18 66 1.1E-6 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS27795 1b5632743253994e72d12d63d684f67d 248 Gene3D G3DSA:1.10.10.10 3 74 2.7E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS13760 3c2a0b0befc98c08c1f9f6d8f58efd56 263 SUPERFAMILY SSF54637 135 259 7.14E-10 T 28-03-2018 IPR029069 HotDog domain CU254_RS13760 3c2a0b0befc98c08c1f9f6d8f58efd56 263 Gene3D G3DSA:3.10.129.10 171 260 0.0016 T 28-03-2018 CU254_RS13760 3c2a0b0befc98c08c1f9f6d8f58efd56 263 Pfam PF13622 Thioesterase-like superfamily 25 258 2.0E-38 T 28-03-2018 CU254_RS13760 3c2a0b0befc98c08c1f9f6d8f58efd56 263 SUPERFAMILY SSF54637 4 109 5.84E-12 T 28-03-2018 IPR029069 HotDog domain CU254_RS13760 3c2a0b0befc98c08c1f9f6d8f58efd56 263 Gene3D G3DSA:3.10.129.10 1 108 1.0E-17 T 28-03-2018 CU254_RS11185 08b146ce0d626dab322c737c8116e6c8 195 Gene3D G3DSA:1.10.10.60 1 60 2.3E-20 T 28-03-2018 CU254_RS11185 08b146ce0d626dab322c737c8116e6c8 195 SUPERFAMILY SSF46689 6 77 2.14E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS11185 08b146ce0d626dab322c737c8116e6c8 195 Gene3D G3DSA:1.10.357.10 61 188 9.8E-18 T 28-03-2018 CU254_RS11185 08b146ce0d626dab322c737c8116e6c8 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 9.6E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS11185 08b146ce0d626dab322c737c8116e6c8 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 9.6E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS11185 08b146ce0d626dab322c737c8116e6c8 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 64 1.2E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS26065 bd0a9ea6eea1eb1fd78eb40fec0c1716 473 Gene3D G3DSA:1.20.1250.20 272 471 2.0E-10 T 28-03-2018 CU254_RS26065 bd0a9ea6eea1eb1fd78eb40fec0c1716 473 Gene3D G3DSA:1.20.1250.20 78 264 6.7E-13 T 28-03-2018 CU254_RS26065 bd0a9ea6eea1eb1fd78eb40fec0c1716 473 SUPERFAMILY SSF103473 78 472 3.53E-29 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS26065 bd0a9ea6eea1eb1fd78eb40fec0c1716 473 Pfam PF07690 Major Facilitator Superfamily 88 430 1.4E-12 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS08200 d2cef6041ecf7837e88cef93b843d5bc 134 SUPERFAMILY SSF54427 10 94 9.76E-8 T 28-03-2018 IPR032710 NTF2-like domain CU254_RS08200 d2cef6041ecf7837e88cef93b843d5bc 134 Gene3D G3DSA:3.10.450.50 9 125 9.9E-9 T 28-03-2018 CU254_RS08200 d2cef6041ecf7837e88cef93b843d5bc 134 Pfam PF12680 SnoaL-like domain 15 95 3.5E-6 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CU254_RS15485 2e9891653ca2e2bb0c7b2c8cf885c825 376 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS15485 2e9891653ca2e2bb0c7b2c8cf885c825 376 Pfam PF00106 short chain dehydrogenase 4 190 6.9E-41 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS15485 2e9891653ca2e2bb0c7b2c8cf885c825 376 SUPERFAMILY SSF51735 4 257 3.78E-57 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS15485 2e9891653ca2e2bb0c7b2c8cf885c825 376 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 5.1E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS15485 2e9891653ca2e2bb0c7b2c8cf885c825 376 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 5.1E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS15485 2e9891653ca2e2bb0c7b2c8cf885c825 376 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 5.1E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS15485 2e9891653ca2e2bb0c7b2c8cf885c825 376 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 204 224 5.1E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS15485 2e9891653ca2e2bb0c7b2c8cf885c825 376 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 5.1E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS15485 2e9891653ca2e2bb0c7b2c8cf885c825 376 Gene3D G3DSA:3.40.50.720 2 265 2.8E-47 T 28-03-2018 CU254_RS35500 77d79b47c1fa56a0c95db60f3c69899e 308 Gene3D G3DSA:3.90.180.10 232 307 2.7E-9 T 28-03-2018 CU254_RS35500 77d79b47c1fa56a0c95db60f3c69899e 308 Pfam PF13602 Zinc-binding dehydrogenase 182 306 1.8E-25 T 28-03-2018 CU254_RS35500 77d79b47c1fa56a0c95db60f3c69899e 308 Gene3D G3DSA:3.90.180.10 1 136 2.4E-38 T 28-03-2018 CU254_RS35500 77d79b47c1fa56a0c95db60f3c69899e 308 Gene3D G3DSA:3.40.50.720 137 231 3.5E-20 T 28-03-2018 CU254_RS35500 77d79b47c1fa56a0c95db60f3c69899e 308 SMART SM00829 10 306 8.7E-13 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CU254_RS35500 77d79b47c1fa56a0c95db60f3c69899e 308 SUPERFAMILY SSF50129 1 145 2.89E-31 T 28-03-2018 IPR011032 GroES-like CU254_RS35500 77d79b47c1fa56a0c95db60f3c69899e 308 SUPERFAMILY SSF51735 118 283 5.52E-29 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS33130 bd52256a3f17d8d85f7d06b8702e80b0 473 Pfam PF13424 Tetratricopeptide repeat 374 448 2.8E-9 T 28-03-2018 CU254_RS33130 bd52256a3f17d8d85f7d06b8702e80b0 473 SUPERFAMILY SSF48452 326 470 7.59E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS33130 bd52256a3f17d8d85f7d06b8702e80b0 473 Gene3D G3DSA:1.10.10.10 394 473 3.7E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS33130 bd52256a3f17d8d85f7d06b8702e80b0 473 Gene3D G3DSA:1.10.10.10 304 393 3.3E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS08570 afbb12015f3b386dd5ac964433fb781d 403 Pfam PF13556 PucR C-terminal helix-turn-helix domain 335 392 6.6E-20 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CU254_RS08570 afbb12015f3b386dd5ac964433fb781d 403 Gene3D G3DSA:1.10.10.60 325 370 5.5E-6 T 28-03-2018 CU254_RS08570 afbb12015f3b386dd5ac964433fb781d 403 Gene3D G3DSA:3.40.930.10 149 283 5.2E-5 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CU254_RS27005 754c2c1e3d3bdba5289248c07fd12bc9 437 Pfam PF03055 Retinal pigment epithelial membrane protein 10 434 1.9E-100 T 28-03-2018 IPR004294 Carotenoid oxygenase GO:0016702|GO:0055114 CU254_RS20645 10a76acc114de124723f147bebd547f3 273 Gene3D G3DSA:1.10.10.10 6 78 8.5E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS20645 10a76acc114de124723f147bebd547f3 273 SUPERFAMILY SSF46785 10 81 5.35E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS20645 10a76acc114de124723f147bebd547f3 273 Pfam PF09339 IclR helix-turn-helix domain 11 59 1.0E-9 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS20645 10a76acc114de124723f147bebd547f3 273 SUPERFAMILY SSF55781 90 246 4.12E-36 T 28-03-2018 IPR029016 GAF domain-like CU254_RS20645 10a76acc114de124723f147bebd547f3 273 Pfam PF01614 Bacterial transcriptional regulator 132 245 8.9E-26 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal CU254_RS20645 10a76acc114de124723f147bebd547f3 273 Gene3D G3DSA:3.30.450.40 79 252 1.4E-37 T 28-03-2018 IPR029016 GAF domain-like CU254_RS20645 10a76acc114de124723f147bebd547f3 273 SMART SM00346 9 98 0.0057 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS01735 145bed68b43c9800a04d44ac60437c76 239 Pfam PF00687 Ribosomal protein L1p/L10e family 31 220 1.4E-50 T 28-03-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein CU254_RS01735 145bed68b43c9800a04d44ac60437c76 239 SUPERFAMILY SSF56808 6 225 8.37E-81 T 28-03-2018 IPR023674 Ribosomal protein L1-like CU254_RS01735 145bed68b43c9800a04d44ac60437c76 239 PIRSF PIRSF002155 1 227 2.6E-73 T 28-03-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS01735 145bed68b43c9800a04d44ac60437c76 239 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 28-03-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS01735 145bed68b43c9800a04d44ac60437c76 239 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 42.144 T 28-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 CU254_RS01735 145bed68b43c9800a04d44ac60437c76 239 Gene3D G3DSA:3.30.190.20 16 130 1.5E-33 T 28-03-2018 CU254_RS01735 145bed68b43c9800a04d44ac60437c76 239 Gene3D G3DSA:3.30.190.20 131 224 7.9E-19 T 28-03-2018 CU254_RS01735 145bed68b43c9800a04d44ac60437c76 239 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 226 5.8E-101 T 28-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 CU254_RS27125 1a1b9701ddbc23d0dc700c0250e80b74 180 Gene3D G3DSA:3.40.50.2020 1 174 4.1E-23 T 28-03-2018 CU254_RS27125 1a1b9701ddbc23d0dc700c0250e80b74 180 Pfam PF00156 Phosphoribosyl transferase domain 47 168 1.0E-11 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CU254_RS27125 1a1b9701ddbc23d0dc700c0250e80b74 180 SUPERFAMILY SSF53271 17 158 9.31E-26 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CU254_RS03390 731a013ff7f63a41cf3bdf6d905fc498 166 Pfam PF04138 GtrA-like protein 13 143 4.6E-18 T 28-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 CU254_RS06455 9cf7fd4d9cfb06873a33d0e0d698452b 166 SUPERFAMILY SSF46785 30 160 5.01E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS06455 9cf7fd4d9cfb06873a33d0e0d698452b 166 SMART SM00347 46 147 1.1E-22 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS06455 9cf7fd4d9cfb06873a33d0e0d698452b 166 Gene3D G3DSA:1.10.10.10 23 165 1.2E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS06455 9cf7fd4d9cfb06873a33d0e0d698452b 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 108 124 2.9E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS06455 9cf7fd4d9cfb06873a33d0e0d698452b 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 137 157 2.9E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS06455 9cf7fd4d9cfb06873a33d0e0d698452b 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 104 2.9E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS06455 9cf7fd4d9cfb06873a33d0e0d698452b 166 ProSitePatterns PS01117 MarR-type HTH domain signature. 87 121 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CU254_RS06455 9cf7fd4d9cfb06873a33d0e0d698452b 166 Pfam PF12802 MarR family 52 111 4.0E-11 T 28-03-2018 CU254_RS23415 80670de6079cc090579905a12a4bf3f1 161 Gene3D G3DSA:2.30.110.10 3 161 2.3E-42 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS23415 80670de6079cc090579905a12a4bf3f1 161 SMART SM00903 14 158 2.5E-55 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CU254_RS23415 80670de6079cc090579905a12a4bf3f1 161 SUPERFAMILY SSF50475 6 159 1.62E-44 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS23415 80670de6079cc090579905a12a4bf3f1 161 Pfam PF01613 Flavin reductase like domain 15 159 2.6E-36 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CU254_RS16595 a713f4a2afd411a6704b48998224aa0c 316 ProSitePatterns PS01053 Arginase family signature. 237 258 - T 28-03-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 CU254_RS16595 a713f4a2afd411a6704b48998224aa0c 316 Hamap MF_00737 Formimidoylglutamase [hutG]. 6 308 39.392 T 28-03-2018 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8 CU254_RS16595 a713f4a2afd411a6704b48998224aa0c 316 Gene3D G3DSA:3.40.800.10 2 310 4.2E-82 T 28-03-2018 CU254_RS16595 a713f4a2afd411a6704b48998224aa0c 316 TIGRFAM TIGR01227 hutG: formimidoylglutamase 32 307 6.5E-89 T 28-03-2018 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8 CU254_RS16595 a713f4a2afd411a6704b48998224aa0c 316 PIRSF PIRSF036979 23 312 1.5E-30 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 CU254_RS16595 a713f4a2afd411a6704b48998224aa0c 316 Pfam PF00491 Arginase family 38 306 8.3E-60 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 CU254_RS16595 a713f4a2afd411a6704b48998224aa0c 316 SUPERFAMILY SSF52768 20 308 3.24E-76 T 28-03-2018 CU254_RS32515 0c7a018cb7efdffd2902dba3e30fe1d2 150 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 6 149 11.052 T 28-03-2018 IPR022907 VapC family GO:0004540 CU254_RS32515 0c7a018cb7efdffd2902dba3e30fe1d2 150 Pfam PF01850 PIN domain 6 143 1.9E-8 T 28-03-2018 IPR002716 PIN domain CU254_RS32515 0c7a018cb7efdffd2902dba3e30fe1d2 150 SUPERFAMILY SSF88723 6 143 6.17E-11 T 28-03-2018 IPR029060 PIN domain-like CU254_RS32515 0c7a018cb7efdffd2902dba3e30fe1d2 150 Gene3D G3DSA:3.40.50.1010 3 149 6.4E-17 T 28-03-2018 IPR029060 PIN domain-like CU254_RS07645 51c8f5e2fb19b6651683643015f15f44 272 Gene3D G3DSA:3.40.50.1820 2 271 7.9E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS07645 51c8f5e2fb19b6651683643015f15f44 272 SUPERFAMILY SSF53474 44 133 1.81E-17 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS07645 51c8f5e2fb19b6651683643015f15f44 272 SUPERFAMILY SSF53474 189 269 1.81E-17 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS39515 ac1f4e9a86f537703082981e2b03aa52 153 Gene3D G3DSA:2.60.200.20 40 152 1.2E-21 T 28-03-2018 CU254_RS39515 ac1f4e9a86f537703082981e2b03aa52 153 Pfam PF16697 Inner membrane component of T3SS, cytoplasmic domain 64 152 1.0E-14 T 28-03-2018 IPR032030 YscD, cytoplasmic domain CU254_RS39515 ac1f4e9a86f537703082981e2b03aa52 153 SMART SM00240 80 130 3.5E-12 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CU254_RS39515 ac1f4e9a86f537703082981e2b03aa52 153 SUPERFAMILY SSF49879 51 152 5.74E-25 T 28-03-2018 IPR008984 SMAD/FHA domain GO:0005515 CU254_RS30470 a772020655b0f479b2f421bf9b0acd88 460 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 258 295 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CU254_RS30470 a772020655b0f479b2f421bf9b0acd88 460 PIRSF PIRSF000521 5 411 2.4E-25 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CU254_RS30470 a772020655b0f479b2f421bf9b0acd88 460 Gene3D G3DSA:3.90.1150.10 5 197 4.1E-42 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS30470 a772020655b0f479b2f421bf9b0acd88 460 Pfam PF00202 Aminotransferase class-III 31 453 7.2E-96 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CU254_RS30470 a772020655b0f479b2f421bf9b0acd88 460 Gene3D G3DSA:3.90.1150.10 273 455 7.2E-47 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS30470 a772020655b0f479b2f421bf9b0acd88 460 SUPERFAMILY SSF53383 21 453 2.09E-125 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS30470 a772020655b0f479b2f421bf9b0acd88 460 Gene3D G3DSA:3.90.1150.10 198 272 0.045 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS11845 6c0d710fc3157c4f598444d614242d45 643 Gene3D G3DSA:3.30.200.20 192 328 1.2E-23 T 28-03-2018 CU254_RS11845 6c0d710fc3157c4f598444d614242d45 643 Pfam PF03109 ABC1 family 208 315 7.6E-28 T 28-03-2018 IPR004147 UbiB domain CU254_RS11845 6c0d710fc3157c4f598444d614242d45 643 Gene3D G3DSA:1.10.510.10 340 414 0.0023 T 28-03-2018 CU254_RS11845 6c0d710fc3157c4f598444d614242d45 643 SUPERFAMILY SSF56112 280 427 1.1E-26 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS11845 6c0d710fc3157c4f598444d614242d45 643 SUPERFAMILY SSF56112 186 245 1.1E-26 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS09095 f87889f96641002ac3c1efdd6fe09d7c 448 Gene3D G3DSA:1.10.287.850 25 107 1.0E-7 T 28-03-2018 CU254_RS09095 f87889f96641002ac3c1efdd6fe09d7c 448 SUPERFAMILY SSF140453 28 104 7.59E-8 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CU254_RS09095 f87889f96641002ac3c1efdd6fe09d7c 448 Gene3D G3DSA:1.20.120.20 275 448 0.43 T 28-03-2018 CU254_RS09095 f87889f96641002ac3c1efdd6fe09d7c 448 Pfam PF06013 Proteins of 100 residues with WXG 30 107 2.7E-7 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CU254_RS30035 773df2bad792078da34fb9665f103ba8 275 PIRSF PIRSF006648 5 274 1.4E-61 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CU254_RS30035 773df2bad792078da34fb9665f103ba8 275 Pfam PF01061 ABC-2 type transporter 30 238 1.8E-25 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CU254_RS39155 6cd2bc165e5c09add36811f1c354818e 221 SUPERFAMILY SSF88946 6 111 5.97E-31 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS39155 6cd2bc165e5c09add36811f1c354818e 221 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 177 8.4E-32 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS39155 6cd2bc165e5c09add36811f1c354818e 221 Pfam PF04542 Sigma-70 region 2 26 92 2.0E-17 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS39155 6cd2bc165e5c09add36811f1c354818e 221 Pfam PF08281 Sigma-70, region 4 123 174 6.3E-17 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS39155 6cd2bc165e5c09add36811f1c354818e 221 SUPERFAMILY SSF88659 115 179 7.66E-16 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS39155 6cd2bc165e5c09add36811f1c354818e 221 Gene3D G3DSA:1.10.1740.10 2 104 1.9E-27 T 28-03-2018 CU254_RS39155 6cd2bc165e5c09add36811f1c354818e 221 Gene3D G3DSA:1.10.10.10 105 183 2.8E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS33405 4e4ad1f0a8c38a4425e0016cb2367469 491 SUPERFAMILY SSF51338 426 487 9.08E-21 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS33405 4e4ad1f0a8c38a4425e0016cb2367469 491 SUPERFAMILY SSF51338 1 55 9.08E-21 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS33405 4e4ad1f0a8c38a4425e0016cb2367469 491 Gene3D G3DSA:2.30.40.10 404 481 1.0E-6 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS33405 4e4ad1f0a8c38a4425e0016cb2367469 491 Pfam PF07969 Amidohydrolase family 45 271 5.7E-9 T 28-03-2018 IPR013108 Amidohydrolase 3 CU254_RS33405 4e4ad1f0a8c38a4425e0016cb2367469 491 Pfam PF01979 Amidohydrolase family 387 469 5.4E-5 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CU254_RS33405 4e4ad1f0a8c38a4425e0016cb2367469 491 SUPERFAMILY SSF51556 56 276 1.66E-28 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS33405 4e4ad1f0a8c38a4425e0016cb2367469 491 SUPERFAMILY SSF51556 327 415 1.66E-28 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS33405 4e4ad1f0a8c38a4425e0016cb2367469 491 Gene3D G3DSA:2.30.40.10 2 68 7.0E-16 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS33405 4e4ad1f0a8c38a4425e0016cb2367469 491 Gene3D G3DSA:3.20.20.140 69 403 1.2E-44 T 28-03-2018 CU254_RS39325 343d6c9a8483138b1b2ebdf64f19b2f5 210 ProSitePatterns PS01081 TetR-type HTH domain signature. 31 62 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CU254_RS39325 343d6c9a8483138b1b2ebdf64f19b2f5 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 63 2.0E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS39325 343d6c9a8483138b1b2ebdf64f19b2f5 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 7.4E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS39325 343d6c9a8483138b1b2ebdf64f19b2f5 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 7.4E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS39325 343d6c9a8483138b1b2ebdf64f19b2f5 210 SUPERFAMILY SSF46689 7 65 9.98E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS39325 343d6c9a8483138b1b2ebdf64f19b2f5 210 Gene3D G3DSA:1.10.10.60 2 60 1.0E-20 T 28-03-2018 CU254_RS39325 343d6c9a8483138b1b2ebdf64f19b2f5 210 Gene3D G3DSA:1.10.357.10 61 208 7.6E-18 T 28-03-2018 CU254_RS29540 3bc187c6a79a50c8ef2487f30d5f1c7f 309 Pfam PF00005 ABC transporter 22 160 5.1E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS29540 3bc187c6a79a50c8ef2487f30d5f1c7f 309 Gene3D G3DSA:3.40.50.300 3 258 1.1E-55 T 28-03-2018 CU254_RS29540 3bc187c6a79a50c8ef2487f30d5f1c7f 309 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS29540 3bc187c6a79a50c8ef2487f30d5f1c7f 309 SMART SM00382 31 216 2.4E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS29540 3bc187c6a79a50c8ef2487f30d5f1c7f 309 SUPERFAMILY SSF52540 6 228 7.79E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS09520 8a51216175a36145a726166a5b230f8f 534 Pfam PF00583 Acetyltransferase (GNAT) family 411 489 2.6E-7 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS09520 8a51216175a36145a726166a5b230f8f 534 SUPERFAMILY SSF55729 357 494 2.34E-17 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS09520 8a51216175a36145a726166a5b230f8f 534 Gene3D G3DSA:3.40.630.30 352 514 1.6E-18 T 28-03-2018 CU254_RS29555 1bd60c024c38b1e2b5f02e8f45a0c08c 203 Gene3D G3DSA:1.10.10.60 1 35 1.6E-11 T 28-03-2018 CU254_RS29555 1bd60c024c38b1e2b5f02e8f45a0c08c 203 Gene3D G3DSA:1.10.357.10 81 196 1.3E-5 T 28-03-2018 CU254_RS29555 1bd60c024c38b1e2b5f02e8f45a0c08c 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 59 3.1E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS29555 1bd60c024c38b1e2b5f02e8f45a0c08c 203 Gene3D G3DSA:1.10.260.40 36 80 3.4E-8 T 28-03-2018 CU254_RS29555 1bd60c024c38b1e2b5f02e8f45a0c08c 203 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 82 190 8.4E-9 T 28-03-2018 CU254_RS29555 1bd60c024c38b1e2b5f02e8f45a0c08c 203 SUPERFAMILY SSF48498 81 190 1.58E-9 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS29555 1bd60c024c38b1e2b5f02e8f45a0c08c 203 SUPERFAMILY SSF46689 3 85 2.21E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS12990 76e241ea69d91fec5962f4a88b1bc9f7 327 SUPERFAMILY SSF81345 3 322 8.5E-62 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CU254_RS12990 76e241ea69d91fec5962f4a88b1bc9f7 327 Pfam PF01032 FecCD transport family 18 322 2.1E-72 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CU254_RS12990 76e241ea69d91fec5962f4a88b1bc9f7 327 Gene3D G3DSA:1.10.3470.10 1 327 4.4E-56 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CU254_RS13030 cd8fad8bc5b04bedb0564e51f7e47d49 364 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 220 357 3.0E-25 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS13030 cd8fad8bc5b04bedb0564e51f7e47d49 364 SUPERFAMILY SSF56645 8 184 8.03E-21 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS13030 cd8fad8bc5b04bedb0564e51f7e47d49 364 Gene3D G3DSA:1.10.540.10 1 119 2.8E-19 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS13030 cd8fad8bc5b04bedb0564e51f7e47d49 364 SUPERFAMILY SSF47203 219 358 4.51E-34 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS13030 cd8fad8bc5b04bedb0564e51f7e47d49 364 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 10 108 7.1E-13 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS13030 cd8fad8bc5b04bedb0564e51f7e47d49 364 Gene3D G3DSA:1.20.140.10 210 360 9.4E-31 T 28-03-2018 CU254_RS22185 aa6d82996c298872cd91981e19353d78 310 SUPERFAMILY SSF51569 7 301 4.71E-57 T 28-03-2018 CU254_RS22185 aa6d82996c298872cd91981e19353d78 310 Pfam PF00701 Dihydrodipicolinate synthetase family 8 301 7.0E-45 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CU254_RS22185 aa6d82996c298872cd91981e19353d78 310 Gene3D G3DSA:3.20.20.70 5 303 1.3E-59 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS22185 aa6d82996c298872cd91981e19353d78 310 Hamap MF_00694 Probable 5-dehydro-4-deoxyglucarate dehydratase. 7 304 41.75 T 28-03-2018 IPR017655 5-dehydro-4-deoxyglucarate dehydratase GO:0016052|GO:0047448 KEGG: 00053+4.2.1.41|MetaCyc: PWY-6486|MetaCyc: PWY-6497|MetaCyc: PWY-6499|MetaCyc: PWY-6501 CU254_RS22185 aa6d82996c298872cd91981e19353d78 310 PIRSF PIRSF001365 4 306 3.2E-48 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CU254_RS22185 aa6d82996c298872cd91981e19353d78 310 SMART SM01130 7 303 3.0E-59 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CU254_RS20485 7773bbb983e32bdf2c264cd494163d05 315 Gene3D G3DSA:3.10.25.10 205 313 2.6E-21 T 28-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CU254_RS20485 7773bbb983e32bdf2c264cd494163d05 315 SUPERFAMILY SSF53328 1 203 2.22E-56 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CU254_RS20485 7773bbb983e32bdf2c264cd494163d05 315 SUPERFAMILY SSF50486 205 308 8.32E-19 T 28-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 CU254_RS20485 7773bbb983e32bdf2c264cd494163d05 315 Pfam PF00551 Formyl transferase 1 170 1.5E-31 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CU254_RS20485 7773bbb983e32bdf2c264cd494163d05 315 Gene3D G3DSA:3.40.50.170 1 204 2.4E-52 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CU254_RS20485 7773bbb983e32bdf2c264cd494163d05 315 Pfam PF02911 Formyl transferase, C-terminal domain 206 305 5.9E-17 T 28-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CU254_RS16340 b636cbb11d8b10edf0ca304a335595bd 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 296 3.0E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS16340 b636cbb11d8b10edf0ca304a335595bd 304 Gene3D G3DSA:1.10.3720.10 24 303 8.5E-51 T 28-03-2018 CU254_RS16340 b636cbb11d8b10edf0ca304a335595bd 304 SUPERFAMILY SSF161098 67 290 1.16E-61 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS24045 22ac862bc0a4737bd7f0162bf0d96fc9 292 Pfam PF04203 Sortase family 87 209 3.7E-16 T 28-03-2018 IPR005754 Sortase family CU254_RS24045 22ac862bc0a4737bd7f0162bf0d96fc9 292 Gene3D G3DSA:2.40.260.10 78 223 1.8E-25 T 28-03-2018 IPR023365 Sortase domain CU254_RS24045 22ac862bc0a4737bd7f0162bf0d96fc9 292 SUPERFAMILY SSF63817 78 209 1.04E-15 T 28-03-2018 IPR023365 Sortase domain CU254_RS06415 6794f1522db036d17bd972b8a8616fb1 331 Gene3D G3DSA:3.40.50.2300 36 158 5.7E-20 T 28-03-2018 CU254_RS06415 6794f1522db036d17bd972b8a8616fb1 331 Pfam PF13407 Periplasmic binding protein domain 46 301 1.7E-49 T 28-03-2018 IPR025997 Periplasmic binding protein CU254_RS06415 6794f1522db036d17bd972b8a8616fb1 331 Gene3D G3DSA:3.40.50.2300 159 315 2.6E-32 T 28-03-2018 CU254_RS06415 6794f1522db036d17bd972b8a8616fb1 331 SUPERFAMILY SSF53822 42 324 7.07E-60 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CU254_RS08150 ede4ecb3c049306d52178a984d561348 368 Pfam PF04055 Radical SAM superfamily 122 295 5.7E-22 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CU254_RS08150 ede4ecb3c049306d52178a984d561348 368 SUPERFAMILY SSF102114 118 342 5.49E-18 T 28-03-2018 CU254_RS08150 ede4ecb3c049306d52178a984d561348 368 PIRSF PIRSF006004 12 368 6.0E-118 T 28-03-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CU254_RS08150 ede4ecb3c049306d52178a984d561348 368 Gene3D G3DSA:3.20.20.70 26 364 1.0E-39 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS08150 ede4ecb3c049306d52178a984d561348 368 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 17 368 65.829 T 28-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CU254_RS08150 ede4ecb3c049306d52178a984d561348 368 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 20 366 3.9E-98 T 28-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CU254_RS18460 53a9ec1684016d1bbcfd3223d07b9b4a 321 SUPERFAMILY SSF51430 8 305 3.54E-46 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS18460 53a9ec1684016d1bbcfd3223d07b9b4a 321 Pfam PF00248 Aldo/keto reductase family 22 298 3.2E-29 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS18460 53a9ec1684016d1bbcfd3223d07b9b4a 321 Gene3D G3DSA:3.20.20.100 7 317 1.4E-45 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS36920 1b00dcf2da259510d771352bde715840 362 Gene3D G3DSA:1.25.40.10 245 361 0.0021 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS34880 0eaadb5346ba6fa2710082e03027ba46 250 Gene3D G3DSA:3.60.15.10 1 250 1.0E-29 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS34880 0eaadb5346ba6fa2710082e03027ba46 250 SUPERFAMILY SSF56281 3 235 2.24E-22 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS34880 0eaadb5346ba6fa2710082e03027ba46 250 Pfam PF13483 Beta-lactamase superfamily domain 3 211 2.0E-17 T 28-03-2018 CU254_RS28965 82d8c0098f9dea1e51d833a1d564fd91 155 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 19 129 1.3E-7 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase CU254_RS28965 82d8c0098f9dea1e51d833a1d564fd91 155 Gene3D G3DSA:3.30.530.20 13 150 1.9E-11 T 28-03-2018 IPR023393 START-like domain CU254_RS28965 82d8c0098f9dea1e51d833a1d564fd91 155 SUPERFAMILY SSF55961 16 140 4.72E-14 T 28-03-2018 CU254_RS30945 d24660bddbc7219197876e67dfad4083 202 Gene3D G3DSA:3.90.950.10 1 201 6.1E-76 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CU254_RS30945 d24660bddbc7219197876e67dfad4083 202 SUPERFAMILY SSF52972 2 198 4.19E-62 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CU254_RS30945 d24660bddbc7219197876e67dfad4083 202 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 2 198 47.307 T 28-03-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 CU254_RS30945 d24660bddbc7219197876e67dfad4083 202 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 3 195 3.6E-49 T 28-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 CU254_RS30945 d24660bddbc7219197876e67dfad4083 202 Pfam PF01725 Ham1 family 4 193 4.2E-55 T 28-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 CU254_RS40740 c5704735548d9c2cba22502b07889925 345 Gene3D G3DSA:1.25.40.10 288 343 0.011 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS40740 c5704735548d9c2cba22502b07889925 345 Gene3D G3DSA:1.10.150.200 254 270 0.25 T 28-03-2018 CU254_RS40740 c5704735548d9c2cba22502b07889925 345 Pfam PF13432 Tetratricopeptide repeat 191 251 2.6E-4 T 28-03-2018 CU254_RS40740 c5704735548d9c2cba22502b07889925 345 Gene3D G3DSA:1.25.40.10 225 239 0.038 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS40740 c5704735548d9c2cba22502b07889925 345 SUPERFAMILY SSF81901 157 324 4.34E-29 T 28-03-2018 CU254_RS40740 c5704735548d9c2cba22502b07889925 345 Gene3D G3DSA:1.25.40.10 12 115 3.3E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS40740 c5704735548d9c2cba22502b07889925 345 Gene3D G3DSA:1.25.40.10 116 205 1.0E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS40740 c5704735548d9c2cba22502b07889925 345 SMART SM00671 282 313 29.0 T 28-03-2018 IPR006597 Sel1-like repeat CU254_RS40740 c5704735548d9c2cba22502b07889925 345 SMART SM00671 26 57 49.0 T 28-03-2018 IPR006597 Sel1-like repeat CU254_RS40740 c5704735548d9c2cba22502b07889925 345 SMART SM00671 218 249 0.031 T 28-03-2018 IPR006597 Sel1-like repeat CU254_RS40740 c5704735548d9c2cba22502b07889925 345 SMART SM00671 58 89 81.0 T 28-03-2018 IPR006597 Sel1-like repeat CU254_RS40740 c5704735548d9c2cba22502b07889925 345 SMART SM00671 250 281 0.006 T 28-03-2018 IPR006597 Sel1-like repeat CU254_RS40740 c5704735548d9c2cba22502b07889925 345 Pfam PF08238 Sel1 repeat 75 88 17.0 T 28-03-2018 IPR006597 Sel1-like repeat CU254_RS40740 c5704735548d9c2cba22502b07889925 345 SUPERFAMILY SSF81901 17 124 1.26E-15 T 28-03-2018 CU254_RS40740 c5704735548d9c2cba22502b07889925 345 Gene3D G3DSA:2.60.40.1180 240 253 3.1E-5 T 28-03-2018 CU254_RS40740 c5704735548d9c2cba22502b07889925 345 Gene3D G3DSA:2.60.40.1180 206 224 0.066 T 28-03-2018 CU254_RS40740 c5704735548d9c2cba22502b07889925 345 Gene3D G3DSA:2.60.40.1180 271 287 4.5E-5 T 28-03-2018 CU254_RS40740 c5704735548d9c2cba22502b07889925 345 Pfam PF13374 Tetratricopeptide repeat 28 53 0.017 T 28-03-2018 CU254_RS16555 f6bc2d0ad2aff04526e23aa3298d91af 200 Gene3D G3DSA:1.10.340.30 25 149 1.1E-6 T 28-03-2018 CU254_RS35935 a9df268c23d8aac37254f260a446b61a 479 Gene3D G3DSA:3.40.50.2000 268 459 1.0E-43 T 28-03-2018 CU254_RS35935 a9df268c23d8aac37254f260a446b61a 479 Gene3D G3DSA:3.40.50.2000 8 267 2.2E-87 T 28-03-2018 CU254_RS35935 a9df268c23d8aac37254f260a446b61a 479 SUPERFAMILY SSF53756 11 473 3.61E-144 T 28-03-2018 CU254_RS35935 a9df268c23d8aac37254f260a446b61a 479 Pfam PF00982 Glycosyltransferase family 20 12 473 2.4E-152 T 28-03-2018 IPR001830 Glycosyl transferase, family 20 GO:0003824|GO:0005992 CU254_RS36305 746148e9cfcc5f8754197b11da68b7dc 315 SMART SM00422 10 79 1.4E-24 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS36305 746148e9cfcc5f8754197b11da68b7dc 315 Gene3D G3DSA:1.10.1660.10 6 65 1.3E-21 T 28-03-2018 CU254_RS36305 746148e9cfcc5f8754197b11da68b7dc 315 Gene3D G3DSA:1.10.1660.10 66 139 2.1E-5 T 28-03-2018 CU254_RS36305 746148e9cfcc5f8754197b11da68b7dc 315 SUPERFAMILY SSF46955 10 114 7.33E-27 T 28-03-2018 IPR009061 Putative DNA-binding domain CU254_RS36305 746148e9cfcc5f8754197b11da68b7dc 315 Pfam PF13411 MerR HTH family regulatory protein 10 77 8.6E-19 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS36305 746148e9cfcc5f8754197b11da68b7dc 315 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 22 35 1.0E-9 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS36305 746148e9cfcc5f8754197b11da68b7dc 315 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 46 66 1.0E-9 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS36305 746148e9cfcc5f8754197b11da68b7dc 315 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 11 22 1.0E-9 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS03515 93c61408d3be3560409fd482f45f45b8 297 SUPERFAMILY SSF53448 2 220 7.67E-44 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS03515 93c61408d3be3560409fd482f45f45b8 297 Pfam PF00535 Glycosyl transferase family 2 6 156 3.1E-21 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CU254_RS03515 93c61408d3be3560409fd482f45f45b8 297 Gene3D G3DSA:3.90.550.10 1 237 8.4E-42 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS05835 df9312d46752395c17058e22949ff0a5 284 Pfam PF04116 Fatty acid hydroxylase superfamily 86 219 6.0E-25 T 28-03-2018 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0008610|GO:0016491|GO:0055114 CU254_RS10480 92c1023d289ae399020fbea14e7567f7 198 Gene3D G3DSA:1.10.10.10 2 102 2.8E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS10480 92c1023d289ae399020fbea14e7567f7 198 Pfam PF03551 Transcriptional regulator PadR-like family 15 89 2.0E-9 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CU254_RS10480 92c1023d289ae399020fbea14e7567f7 198 SUPERFAMILY SSF46785 11 179 2.48E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS26720 c8d530a3cc9f7dcba93f9b25c4377e36 792 Pfam PF03772 Competence protein 232 493 5.5E-51 T 28-03-2018 IPR004477 ComEC/Rec2-related protein CU254_RS26720 c8d530a3cc9f7dcba93f9b25c4377e36 792 SUPERFAMILY SSF56281 527 771 2.17E-39 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS26720 c8d530a3cc9f7dcba93f9b25c4377e36 792 Pfam PF00753 Metallo-beta-lactamase superfamily 537 717 6.1E-11 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS26720 c8d530a3cc9f7dcba93f9b25c4377e36 792 Pfam PF13567 Domain of unknown function (DUF4131) 34 180 1.3E-7 T 28-03-2018 IPR025405 Domain of unknown function DUF4131 CU254_RS26720 c8d530a3cc9f7dcba93f9b25c4377e36 792 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 254 426 6.2E-19 T 28-03-2018 IPR004477 ComEC/Rec2-related protein CU254_RS26720 c8d530a3cc9f7dcba93f9b25c4377e36 792 Gene3D G3DSA:3.60.15.10 532 738 2.4E-31 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS26720 c8d530a3cc9f7dcba93f9b25c4377e36 792 SMART SM00849 539 739 8.6E-10 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS33335 534bf027f5ef0408fda4b5de1ea42f28 213 SUPERFAMILY SSF46894 137 195 1.33E-15 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS33335 534bf027f5ef0408fda4b5de1ea42f28 213 SUPERFAMILY SSF52172 1 132 9.25E-21 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS33335 534bf027f5ef0408fda4b5de1ea42f28 213 ProSitePatterns PS00622 LuxR-type HTH domain signature. 163 190 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS33335 534bf027f5ef0408fda4b5de1ea42f28 213 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 195 5.4E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS33335 534bf027f5ef0408fda4b5de1ea42f28 213 SMART SM00421 146 207 1.2E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS33335 534bf027f5ef0408fda4b5de1ea42f28 213 Gene3D G3DSA:3.40.50.2300 1 131 1.4E-27 T 28-03-2018 CU254_RS33335 534bf027f5ef0408fda4b5de1ea42f28 213 Pfam PF00072 Response regulator receiver domain 3 108 1.4E-17 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS33335 534bf027f5ef0408fda4b5de1ea42f28 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 179 2.4E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS33335 534bf027f5ef0408fda4b5de1ea42f28 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 179 191 2.4E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS33335 534bf027f5ef0408fda4b5de1ea42f28 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 163 2.4E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS33335 534bf027f5ef0408fda4b5de1ea42f28 213 SMART SM00448 1 120 1.1E-10 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS33335 534bf027f5ef0408fda4b5de1ea42f28 213 Gene3D G3DSA:1.10.10.10 132 212 4.0E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS19075 3449ce7e0a28dfc7d6c4858e2ee9e827 311 SUPERFAMILY SSF56529 63 291 4.84E-66 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CU254_RS19075 3449ce7e0a28dfc7d6c4858e2ee9e827 311 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 64 290 2.7E-59 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CU254_RS19075 3449ce7e0a28dfc7d6c4858e2ee9e827 311 Gene3D G3DSA:3.90.850.10 21 298 6.8E-65 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CU254_RS02910 d0894209ac3fbadd3bb4aace3324a94b 310 Gene3D G3DSA:1.20.58.370 13 60 1.9E-4 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain CU254_RS02910 d0894209ac3fbadd3bb4aace3324a94b 310 Gene3D G3DSA:1.10.3720.10 78 304 1.7E-42 T 28-03-2018 CU254_RS02910 d0894209ac3fbadd3bb4aace3324a94b 310 SUPERFAMILY SSF161098 72 292 1.07E-53 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS02910 d0894209ac3fbadd3bb4aace3324a94b 310 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 104 303 2.9E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS22780 74149542df5ec5df46e63c26dc64068d 172 Gene3D G3DSA:2.40.380.10 1 165 2.3E-51 T 28-03-2018 IPR007295 Domain of unknown function DUF402 CU254_RS22780 74149542df5ec5df46e63c26dc64068d 172 PIRSF PIRSF012622 1 172 7.0E-58 T 28-03-2018 IPR014465 Uncharacterised conserved protein UCP012622 CU254_RS22780 74149542df5ec5df46e63c26dc64068d 172 SUPERFAMILY SSF159234 4 169 8.5E-49 T 28-03-2018 IPR007295 Domain of unknown function DUF402 CU254_RS22780 74149542df5ec5df46e63c26dc64068d 172 Pfam PF04167 Protein of unknown function (DUF402) 53 120 6.9E-14 T 28-03-2018 IPR007295 Domain of unknown function DUF402 CU254_RS32550 69978a1a8b54b0ab3194b4c4f5ab9b80 172 Pfam PF01381 Helix-turn-helix 10 52 1.3E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS32550 69978a1a8b54b0ab3194b4c4f5ab9b80 172 SUPERFAMILY SSF47413 1 61 7.51E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS32550 69978a1a8b54b0ab3194b4c4f5ab9b80 172 Gene3D G3DSA:1.10.260.40 1 60 2.2E-16 T 28-03-2018 CU254_RS32550 69978a1a8b54b0ab3194b4c4f5ab9b80 172 SMART SM00530 6 61 1.1E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS40045 351b9b4ac33754cca451b822602ce05a 106 Gene3D G3DSA:3.30.70.120 1 106 5.8E-35 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CU254_RS40045 351b9b4ac33754cca451b822602ce05a 106 Pfam PF03091 CutA1 divalent ion tolerance protein 6 103 7.3E-31 T 28-03-2018 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 CU254_RS40045 351b9b4ac33754cca451b822602ce05a 106 SUPERFAMILY SSF54913 2 105 1.3E-33 T 28-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta CU254_RS17805 f61851d5286b602439f0a1ef74d2f7a0 182 SMART SM00471 29 143 2.0E-10 T 28-03-2018 IPR003607 HD/PDEase domain CU254_RS17805 f61851d5286b602439f0a1ef74d2f7a0 182 Pfam PF13023 HD domain 12 149 2.7E-27 T 28-03-2018 IPR006674 HD domain CU254_RS17805 f61851d5286b602439f0a1ef74d2f7a0 182 Gene3D G3DSA:1.10.3210.10 2 180 7.2E-39 T 28-03-2018 CU254_RS17805 f61851d5286b602439f0a1ef74d2f7a0 182 SUPERFAMILY SSF109604 2 154 5.23E-34 T 28-03-2018 CU254_RS06645 9e5a65ae0038ba00f9bcfd6a3b908eb9 474 Gene3D G3DSA:1.10.260.40 1 73 1.1E-15 T 28-03-2018 CU254_RS06645 9e5a65ae0038ba00f9bcfd6a3b908eb9 474 Pfam PF09856 Predicted transcriptional regulator (DUF2083) 312 468 3.7E-70 T 28-03-2018 IPR018653 Domain of unknown function DUF2083,transcriptional regulator CU254_RS06645 9e5a65ae0038ba00f9bcfd6a3b908eb9 474 SMART SM00530 9 64 5.7E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS06645 9e5a65ae0038ba00f9bcfd6a3b908eb9 474 Pfam PF06114 IrrE N-terminal-like domain 188 311 2.7E-18 T 28-03-2018 IPR010359 IrrE N-terminal-like domain CU254_RS06645 9e5a65ae0038ba00f9bcfd6a3b908eb9 474 SUPERFAMILY SSF47413 3 67 3.66E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS06645 9e5a65ae0038ba00f9bcfd6a3b908eb9 474 Pfam PF13560 Helix-turn-helix domain 7 61 6.8E-12 T 28-03-2018 CU254_RS06645 9e5a65ae0038ba00f9bcfd6a3b908eb9 474 PIRSF PIRSF019251 1 473 1.0E-191 T 28-03-2018 IPR026281 HTH-type transcriptional regulator RamB GO:0006355 CU254_RS17915 11bb6ce4ef3d4516aad18b74ef3c1392 315 Pfam PF00561 alpha/beta hydrolase fold 34 294 1.6E-23 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS17915 11bb6ce4ef3d4516aad18b74ef3c1392 315 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 61 72 2.8E-11 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CU254_RS17915 11bb6ce4ef3d4516aad18b74ef3c1392 315 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 109 123 2.8E-11 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CU254_RS17915 11bb6ce4ef3d4516aad18b74ef3c1392 315 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 35 43 2.8E-11 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CU254_RS17915 11bb6ce4ef3d4516aad18b74ef3c1392 315 SUPERFAMILY SSF53474 2 295 6.3E-50 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS17915 11bb6ce4ef3d4516aad18b74ef3c1392 315 PIRSF PIRSF006431 1 315 5.8E-112 T 28-03-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 CU254_RS17915 11bb6ce4ef3d4516aad18b74ef3c1392 315 PRINTS PR00111 Alpha/beta hydrolase fold signature 109 122 4.7E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS17915 11bb6ce4ef3d4516aad18b74ef3c1392 315 PRINTS PR00111 Alpha/beta hydrolase fold signature 58 73 4.7E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS17915 11bb6ce4ef3d4516aad18b74ef3c1392 315 PRINTS PR00111 Alpha/beta hydrolase fold signature 123 136 4.7E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS17915 11bb6ce4ef3d4516aad18b74ef3c1392 315 TIGRFAM TIGR01249 pro_imino_pep_1: prolyl aminopeptidase 7 311 1.5E-96 T 28-03-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 CU254_RS17915 11bb6ce4ef3d4516aad18b74ef3c1392 315 Gene3D G3DSA:3.40.50.1820 2 313 7.0E-53 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS18740 a8114a017bd94f1b5ba28fc8f108ec2d 404 PRINTS PR00359 B-class P450 signature 200 222 3.5E-60 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS18740 a8114a017bd94f1b5ba28fc8f108ec2d 404 PRINTS PR00359 B-class P450 signature 352 363 3.5E-60 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS18740 a8114a017bd94f1b5ba28fc8f108ec2d 404 PRINTS PR00359 B-class P450 signature 294 321 3.5E-60 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS18740 a8114a017bd94f1b5ba28fc8f108ec2d 404 PRINTS PR00359 B-class P450 signature 343 352 3.5E-60 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS18740 a8114a017bd94f1b5ba28fc8f108ec2d 404 PRINTS PR00359 B-class P450 signature 163 178 3.5E-60 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS18740 a8114a017bd94f1b5ba28fc8f108ec2d 404 PRINTS PR00359 B-class P450 signature 277 288 3.5E-60 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS18740 a8114a017bd94f1b5ba28fc8f108ec2d 404 PRINTS PR00359 B-class P450 signature 99 110 3.5E-60 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS18740 a8114a017bd94f1b5ba28fc8f108ec2d 404 PRINTS PR00359 B-class P450 signature 322 337 3.5E-60 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS18740 a8114a017bd94f1b5ba28fc8f108ec2d 404 PRINTS PR00359 B-class P450 signature 146 162 3.5E-60 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS18740 a8114a017bd94f1b5ba28fc8f108ec2d 404 Gene3D G3DSA:1.10.630.10 10 404 1.7E-75 T 28-03-2018 CU254_RS18740 a8114a017bd94f1b5ba28fc8f108ec2d 404 SUPERFAMILY SSF48264 14 403 2.23E-97 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS18740 a8114a017bd94f1b5ba28fc8f108ec2d 404 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 345 354 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CU254_RS18740 a8114a017bd94f1b5ba28fc8f108ec2d 404 PRINTS PR00385 P450 superfamily signature 343 352 8.4E-8 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS18740 a8114a017bd94f1b5ba28fc8f108ec2d 404 PRINTS PR00385 P450 superfamily signature 277 288 8.4E-8 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS18740 a8114a017bd94f1b5ba28fc8f108ec2d 404 PRINTS PR00385 P450 superfamily signature 242 259 8.4E-8 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS18740 a8114a017bd94f1b5ba28fc8f108ec2d 404 PRINTS PR00385 P450 superfamily signature 352 363 8.4E-8 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS18740 a8114a017bd94f1b5ba28fc8f108ec2d 404 Pfam PF00067 Cytochrome P450 224 373 1.8E-23 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS38090 db3aff73a9334386d99fa8fd87adcd07 293 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 92 3.2E-10 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CU254_RS38090 db3aff73a9334386d99fa8fd87adcd07 293 SUPERFAMILY SSF51735 1 282 8.78E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS38090 db3aff73a9334386d99fa8fd87adcd07 293 Gene3D G3DSA:3.90.25.10 162 289 2.5E-13 T 28-03-2018 CU254_RS38090 db3aff73a9334386d99fa8fd87adcd07 293 Gene3D G3DSA:3.40.50.720 1 129 2.1E-15 T 28-03-2018 CU254_RS32235 15f50ab5babc89718e94cd2e82fa0be4 149 Pfam PF04075 F420H(2)-dependent quinone reductase 27 115 2.8E-6 T 28-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CU254_RS32235 15f50ab5babc89718e94cd2e82fa0be4 149 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 30 113 1.5E-13 T 28-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CU254_RS32235 15f50ab5babc89718e94cd2e82fa0be4 149 Gene3D G3DSA:2.30.110.10 2 149 1.3E-16 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS16140 74a7dc2058aa6966897bfb282ffd2fb4 445 SUPERFAMILY SSF103473 6 413 1.14E-36 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS16140 74a7dc2058aa6966897bfb282ffd2fb4 445 Pfam PF07690 Major Facilitator Superfamily 9 353 1.1E-21 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS16140 74a7dc2058aa6966897bfb282ffd2fb4 445 Gene3D G3DSA:1.20.1250.20 203 443 3.3E-9 T 28-03-2018 CU254_RS16140 74a7dc2058aa6966897bfb282ffd2fb4 445 Gene3D G3DSA:1.20.1250.20 1 194 3.8E-19 T 28-03-2018 CU254_RS36325 17cd7e85d9ba614f473953bca66c1764 204 Gene3D G3DSA:3.30.1130.10 69 203 1.2E-57 T 28-03-2018 CU254_RS36325 17cd7e85d9ba614f473953bca66c1764 204 Pfam PF01227 GTP cyclohydrolase I 23 200 2.9E-74 T 28-03-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CU254_RS36325 17cd7e85d9ba614f473953bca66c1764 204 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 24 201 3.0E-70 T 28-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CU254_RS36325 17cd7e85d9ba614f473953bca66c1764 204 Gene3D G3DSA:1.10.286.10 20 68 1.3E-23 T 28-03-2018 CU254_RS36325 17cd7e85d9ba614f473953bca66c1764 204 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 18 201 41.349 T 28-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CU254_RS36325 17cd7e85d9ba614f473953bca66c1764 204 SUPERFAMILY SSF55620 13 201 5.71E-75 T 28-03-2018 CU254_RS36325 17cd7e85d9ba614f473953bca66c1764 204 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 128 138 - T 28-03-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CU254_RS39770 f1ce217603b4582842b3613aa2abdd52 259 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 249 4.3E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS39770 f1ce217603b4582842b3613aa2abdd52 259 Gene3D G3DSA:1.10.3720.10 54 256 1.6E-24 T 28-03-2018 CU254_RS39770 f1ce217603b4582842b3613aa2abdd52 259 SUPERFAMILY SSF161098 59 245 1.31E-29 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS17500 224f13950b2ea2aa86c234048e52c0d7 253 Gene3D G3DSA:3.10.180.10 135 253 1.5E-14 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS17500 224f13950b2ea2aa86c234048e52c0d7 253 SUPERFAMILY SSF54593 148 250 1.19E-15 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS17500 224f13950b2ea2aa86c234048e52c0d7 253 Gene3D G3DSA:3.10.180.10 2 133 2.5E-17 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS17500 224f13950b2ea2aa86c234048e52c0d7 253 SUPERFAMILY SSF54593 12 128 6.31E-19 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS17500 224f13950b2ea2aa86c234048e52c0d7 253 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 18 117 1.4E-4 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CU254_RS38475 b21d2262a660298d41171d0ef3fc5a56 612 Pfam PF12229 Putative peptidoglycan binding domain 270 368 2.9E-11 T 28-03-2018 IPR022029 Putative peptidoglycan binding domain CU254_RS38475 b21d2262a660298d41171d0ef3fc5a56 612 Pfam PF04294 VanW like protein 413 537 1.7E-26 T 28-03-2018 IPR007391 Vancomycin resistance VanW CU254_RS31630 fa180a5c6c5431259ab10d9d1afe54d1 308 Pfam PF08281 Sigma-70, region 4 126 174 4.0E-7 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS31630 fa180a5c6c5431259ab10d9d1afe54d1 308 SUPERFAMILY SSF88946 28 111 5.49E-10 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS31630 fa180a5c6c5431259ab10d9d1afe54d1 308 SUPERFAMILY SSF88659 103 183 6.17E-7 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS31630 fa180a5c6c5431259ab10d9d1afe54d1 308 Gene3D G3DSA:1.10.10.10 93 171 1.4E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS31630 fa180a5c6c5431259ab10d9d1afe54d1 308 Pfam PF04542 Sigma-70 region 2 30 95 7.0E-10 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS31630 fa180a5c6c5431259ab10d9d1afe54d1 308 Gene3D G3DSA:1.10.1740.10 17 92 3.9E-11 T 28-03-2018 CU254_RS31630 fa180a5c6c5431259ab10d9d1afe54d1 308 Gene3D G3DSA:3.10.450.50 172 305 1.5E-10 T 28-03-2018 CU254_RS31630 fa180a5c6c5431259ab10d9d1afe54d1 308 SUPERFAMILY SSF54427 195 284 7.83E-9 T 28-03-2018 IPR032710 NTF2-like domain CU254_RS19210 ae1a4f83055771c3aa5aae9fde220294 192 ProSitePatterns PS01081 TetR-type HTH domain signature. 24 54 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CU254_RS19210 ae1a4f83055771c3aa5aae9fde220294 192 Gene3D G3DSA:1.10.357.10 59 192 3.8E-21 T 28-03-2018 CU254_RS19210 ae1a4f83055771c3aa5aae9fde220294 192 SUPERFAMILY SSF48498 80 191 5.01E-22 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS19210 ae1a4f83055771c3aa5aae9fde220294 192 Gene3D G3DSA:1.10.10.60 2 58 6.8E-16 T 28-03-2018 CU254_RS19210 ae1a4f83055771c3aa5aae9fde220294 192 SUPERFAMILY SSF46689 3 75 9.75E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS19210 ae1a4f83055771c3aa5aae9fde220294 192 Pfam PF16925 Bacterial transcriptional repressor C-terminal 98 188 1.3E-6 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS19210 ae1a4f83055771c3aa5aae9fde220294 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 58 1.4E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS31085 2ae8f34a54e7171ac3c5386e21664eea 177 Pfam PF11706 CGNR zinc finger 129 171 2.4E-12 T 28-03-2018 IPR021005 Zinc finger, CGNR CU254_RS31085 2ae8f34a54e7171ac3c5386e21664eea 177 SUPERFAMILY SSF160904 1 170 9.81E-37 T 28-03-2018 CU254_RS31085 2ae8f34a54e7171ac3c5386e21664eea 177 Gene3D G3DSA:1.10.3300.10 9 173 2.5E-32 T 28-03-2018 IPR023286 ABATE domain CU254_RS13070 4d088c51fc40f732b9759b791aeb4793 181 Gene3D G3DSA:3.40.630.30 2 181 1.2E-26 T 28-03-2018 CU254_RS13070 4d088c51fc40f732b9759b791aeb4793 181 Pfam PF13302 Acetyltransferase (GNAT) domain 11 144 5.3E-24 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS13070 4d088c51fc40f732b9759b791aeb4793 181 SUPERFAMILY SSF55729 3 149 2.51E-31 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS40245 e764351b4d2eebd80d5d49499fed560b 317 Gene3D G3DSA:3.30.360.10 130 317 1.2E-17 T 28-03-2018 CU254_RS40245 e764351b4d2eebd80d5d49499fed560b 317 Gene3D G3DSA:3.40.50.720 1 129 2.8E-33 T 28-03-2018 CU254_RS40245 e764351b4d2eebd80d5d49499fed560b 317 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 117 8.9E-19 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CU254_RS40245 e764351b4d2eebd80d5d49499fed560b 317 SUPERFAMILY SSF51735 4 149 7.82E-31 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS40245 e764351b4d2eebd80d5d49499fed560b 317 SUPERFAMILY SSF55347 123 226 1.87E-10 T 28-03-2018 CU254_RS28490 85c08f0a27fe47cbe9e69c31959b5127 450 Gene3D G3DSA:3.40.50.300 2 175 6.3E-34 T 28-03-2018 CU254_RS28490 85c08f0a27fe47cbe9e69c31959b5127 450 SUPERFAMILY SSF52317 257 440 2.21E-26 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS28490 85c08f0a27fe47cbe9e69c31959b5127 450 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 190 1.0E-15 T 28-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CU254_RS28490 85c08f0a27fe47cbe9e69c31959b5127 450 SUPERFAMILY SSF52540 4 196 4.04E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS28490 85c08f0a27fe47cbe9e69c31959b5127 450 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 255 429 2.9E-22 T 28-03-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 CU254_RS28490 85c08f0a27fe47cbe9e69c31959b5127 450 TIGRFAM TIGR00379 cobB: cobyrinic acid a,c-diamide synthase 4 437 8.7E-123 T 28-03-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 CU254_RS28490 85c08f0a27fe47cbe9e69c31959b5127 450 Gene3D G3DSA:3.40.50.880 238 402 9.7E-23 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS28490 85c08f0a27fe47cbe9e69c31959b5127 450 Hamap MF_00027 Cobyrinate a,c-diamide synthase [cbiA]. 2 430 39.944 T 28-03-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 CU254_RS18415 ae88bdf919c83d5c1ba2566089ff216b 258 Gene3D G3DSA:3.20.20.80 30 257 6.5E-63 T 28-03-2018 CU254_RS18415 ae88bdf919c83d5c1ba2566089ff216b 258 SUPERFAMILY SSF51445 48 251 1.61E-60 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS18415 ae88bdf919c83d5c1ba2566089ff216b 258 Pfam PF01183 Glycosyl hydrolases family 25 52 235 1.3E-44 T 28-03-2018 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 CU254_RS18415 ae88bdf919c83d5c1ba2566089ff216b 258 SMART SM00641 48 157 4.3E-39 T 28-03-2018 IPR018077 Glycoside hydrolase, family 25 subgroup CU254_RS37350 3825e9cb9141a6c91419dc5800d74302 610 SUPERFAMILY SSF49899 359 605 1.49E-22 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CU254_RS37350 3825e9cb9141a6c91419dc5800d74302 610 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 5 26 0.0011 T 28-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal CU254_RS37350 3825e9cb9141a6c91419dc5800d74302 610 Gene3D G3DSA:2.60.120.200 360 607 1.2E-25 T 28-03-2018 CU254_RS37350 3825e9cb9141a6c91419dc5800d74302 610 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 443 605 1.5E-13 T 28-03-2018 CU254_RS37350 3825e9cb9141a6c91419dc5800d74302 610 SUPERFAMILY SSF56300 47 271 9.91E-20 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CU254_RS37350 3825e9cb9141a6c91419dc5800d74302 610 SMART SM00560 452 604 0.0045 T 28-03-2018 IPR006558 LamG-like jellyroll fold CU254_RS37350 3825e9cb9141a6c91419dc5800d74302 610 Gene3D G3DSA:3.60.21.10 47 298 1.7E-18 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CU254_RS07760 5e02d940c1112f1f6875fb99109ae9a5 404 Hamap MF_01270 Anhydro-N-acetylmuramic acid kinase [anmK]. 9 378 33.245 T 28-03-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 CU254_RS07760 5e02d940c1112f1f6875fb99109ae9a5 404 Gene3D G3DSA:3.30.420.40 205 383 2.5E-18 T 28-03-2018 CU254_RS07760 5e02d940c1112f1f6875fb99109ae9a5 404 Gene3D G3DSA:3.30.420.40 8 193 1.1E-46 T 28-03-2018 CU254_RS07760 5e02d940c1112f1f6875fb99109ae9a5 404 Pfam PF03702 Anhydro-N-acetylmuramic acid kinase 10 377 1.0E-103 T 28-03-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 CU254_RS07760 5e02d940c1112f1f6875fb99109ae9a5 404 SUPERFAMILY SSF53067 78 116 7.77E-11 T 28-03-2018 CU254_RS07760 5e02d940c1112f1f6875fb99109ae9a5 404 SUPERFAMILY SSF53067 149 328 7.77E-11 T 28-03-2018 CU254_RS13575 c5679a1e87fa45ce2dc58d6cdf399b7e 222 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 52 1.1E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS13575 c5679a1e87fa45ce2dc58d6cdf399b7e 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 54 1.4E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS13575 c5679a1e87fa45ce2dc58d6cdf399b7e 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 1.4E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS13575 c5679a1e87fa45ce2dc58d6cdf399b7e 222 Gene3D G3DSA:1.10.357.10 51 186 2.2E-24 T 28-03-2018 CU254_RS13575 c5679a1e87fa45ce2dc58d6cdf399b7e 222 SUPERFAMILY SSF46689 6 68 4.25E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS13575 c5679a1e87fa45ce2dc58d6cdf399b7e 222 Gene3D G3DSA:1.10.10.60 6 50 3.7E-17 T 28-03-2018 CU254_RS00205 20693f41a1eafe75960993b12715e7f6 255 Gene3D G3DSA:3.40.50.150 8 255 3.0E-34 T 28-03-2018 CU254_RS00205 20693f41a1eafe75960993b12715e7f6 255 Pfam PF08242 Methyltransferase domain 46 144 5.0E-13 T 28-03-2018 IPR013217 Methyltransferase type 12 CU254_RS00205 20693f41a1eafe75960993b12715e7f6 255 SUPERFAMILY SSF53335 30 220 3.07E-30 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS04050 471718f92a24b2041465f6c149a2433f 316 SUPERFAMILY SSF48239 39 313 2.51E-14 T 28-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CU254_RS04050 471718f92a24b2041465f6c149a2433f 316 Gene3D G3DSA:1.50.10.20 139 312 6.0E-9 T 28-03-2018 CU254_RS04050 471718f92a24b2041465f6c149a2433f 316 Gene3D G3DSA:1.50.10.20 15 137 1.0E-4 T 28-03-2018 CU254_RS02735 a954fa8bd5081864312c74b0eed965b7 103 Gene3D G3DSA:2.30.30.410 26 103 1.2E-5 T 28-03-2018 CU254_RS03310 1466f2901f69c76c9a7d39f503fb6adc 278 Pfam PF04185 Phosphoesterase family 51 261 2.6E-30 T 28-03-2018 IPR007312 Phosphoesterase GO:0016788 CU254_RS03310 1466f2901f69c76c9a7d39f503fb6adc 278 SUPERFAMILY SSF53649 35 178 3.49E-7 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CU254_RS03310 1466f2901f69c76c9a7d39f503fb6adc 278 Gene3D G3DSA:3.40.720.10 23 263 5.9E-6 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CU254_RS33385 caf9a27caffe7115899448ae20e62e4e 551 Gene3D G3DSA:1.10.10.60 466 518 0.0011 T 28-03-2018 CU254_RS33385 caf9a27caffe7115899448ae20e62e4e 551 Pfam PF13556 PucR C-terminal helix-turn-helix domain 482 539 1.5E-18 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CU254_RS33385 caf9a27caffe7115899448ae20e62e4e 551 Gene3D G3DSA:3.30.450.40 141 282 1.2E-6 T 28-03-2018 IPR029016 GAF domain-like CU254_RS32020 ffcdf121a1290a5cffa66a7d313a6553 520 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 5 167 7.7E-32 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CU254_RS32020 ffcdf121a1290a5cffa66a7d313a6553 520 Gene3D G3DSA:3.40.50.970 322 519 1.9E-35 T 28-03-2018 CU254_RS32020 ffcdf121a1290a5cffa66a7d313a6553 520 SUPERFAMILY SSF52518 337 518 3.75E-43 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS32020 ffcdf121a1290a5cffa66a7d313a6553 520 Gene3D G3DSA:3.40.50.970 1 170 4.5E-37 T 28-03-2018 CU254_RS32020 ffcdf121a1290a5cffa66a7d313a6553 520 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 377 514 1.2E-29 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CU254_RS32020 ffcdf121a1290a5cffa66a7d313a6553 520 SUPERFAMILY SSF52518 4 182 1.82E-37 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS32020 ffcdf121a1290a5cffa66a7d313a6553 520 Gene3D G3DSA:3.40.50.1220 181 321 8.5E-6 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CU254_RS23685 b551c5917b234825b0e30a0365fb9934 452 Gene3D G3DSA:1.20.1250.20 252 452 6.7E-29 T 28-03-2018 CU254_RS23685 b551c5917b234825b0e30a0365fb9934 452 SUPERFAMILY SSF103473 248 445 6.54E-67 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS23685 b551c5917b234825b0e30a0365fb9934 452 SUPERFAMILY SSF103473 20 205 6.54E-67 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS23685 b551c5917b234825b0e30a0365fb9934 452 Pfam PF07690 Major Facilitator Superfamily 28 408 7.3E-48 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS23685 b551c5917b234825b0e30a0365fb9934 452 Gene3D G3DSA:1.20.1250.20 19 209 4.1E-24 T 28-03-2018 CU254_RS42300 bd0217cde5010abdac3628aafe731340 327 Pfam PF00877 NlpC/P60 family 212 308 3.9E-23 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CU254_RS42300 bd0217cde5010abdac3628aafe731340 327 Gene3D G3DSA:3.90.1720.10 194 312 1.6E-30 T 28-03-2018 CU254_RS42300 bd0217cde5010abdac3628aafe731340 327 SUPERFAMILY SSF54001 198 307 2.16E-33 T 28-03-2018 CU254_RS00300 61b359bc9e50bfffc16a547bb09d7827 339 Gene3D G3DSA:3.60.40.10 15 313 5.9E-10 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CU254_RS00300 61b359bc9e50bfffc16a547bb09d7827 339 SUPERFAMILY SSF81606 32 274 8.5E-10 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CU254_RS16690 c2157bab9562198e8106fac10dbb1814 528 SUPERFAMILY SSF51445 9 465 1.29E-118 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS16690 c2157bab9562198e8106fac10dbb1814 528 Pfam PF00128 Alpha amylase, catalytic domain 33 384 5.8E-73 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CU254_RS16690 c2157bab9562198e8106fac10dbb1814 528 Gene3D G3DSA:3.20.20.80 7 469 1.0E-114 T 28-03-2018 CU254_RS16690 c2157bab9562198e8106fac10dbb1814 528 SMART SM00642 18 406 2.5E-118 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CU254_RS16690 c2157bab9562198e8106fac10dbb1814 528 Gene3D G3DSA:2.60.40.1180 477 526 7.3E-4 T 28-03-2018 CU254_RS28665 76694e45766e83e57238cd82f9638361 202 Gene3D G3DSA:3.30.420.10 1 178 4.8E-30 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS28665 76694e45766e83e57238cd82f9638361 202 Pfam PF00929 Exonuclease 6 168 7.3E-32 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CU254_RS28665 76694e45766e83e57238cd82f9638361 202 Hamap MF_00045 Oligoribonuclease [orn]. 1 180 37.944 T 28-03-2018 IPR022894 Oligoribonuclease GO:0000175 CU254_RS28665 76694e45766e83e57238cd82f9638361 202 SUPERFAMILY SSF53098 3 176 7.59E-42 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS28665 76694e45766e83e57238cd82f9638361 202 SMART SM00479 4 179 3.7E-28 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CU254_RS12575 d5d9a44fcf8199b240eda315c73e0d4c 394 Gene3D G3DSA:1.20.1250.20 197 391 1.1E-21 T 28-03-2018 CU254_RS12575 d5d9a44fcf8199b240eda315c73e0d4c 394 Gene3D G3DSA:1.20.1250.20 1 187 6.3E-18 T 28-03-2018 CU254_RS12575 d5d9a44fcf8199b240eda315c73e0d4c 394 Pfam PF07690 Major Facilitator Superfamily 21 343 8.4E-25 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS12575 d5d9a44fcf8199b240eda315c73e0d4c 394 SUPERFAMILY SSF103473 5 378 4.84E-46 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS34370 ff61b2f3e024773a443a83c7250c0616 186 TIGRFAM TIGR03086 TIGR03086: TIGR03086 family protein 8 183 3.2E-49 T 28-03-2018 IPR017520 Conserved hypothetical protein CHP03086 CU254_RS34370 ff61b2f3e024773a443a83c7250c0616 186 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 7 126 2.0E-17 T 28-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CU254_RS34370 ff61b2f3e024773a443a83c7250c0616 186 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 7 183 6.1E-27 T 28-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CU254_RS34370 ff61b2f3e024773a443a83c7250c0616 186 SUPERFAMILY SSF109854 3 132 2.01E-25 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CU254_RS34370 ff61b2f3e024773a443a83c7250c0616 186 Gene3D G3DSA:1.20.120.450 3 132 4.4E-24 T 28-03-2018 CU254_RS18575 a2e6018bd7cdbf74894f3c458a24d80c 453 Gene3D G3DSA:1.10.287.130 224 296 1.4E-11 T 28-03-2018 CU254_RS18575 a2e6018bd7cdbf74894f3c458a24d80c 453 SUPERFAMILY SSF158472 181 230 3.53E-6 T 28-03-2018 CU254_RS18575 a2e6018bd7cdbf74894f3c458a24d80c 453 Gene3D G3DSA:3.30.565.10 306 453 4.9E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS18575 a2e6018bd7cdbf74894f3c458a24d80c 453 SMART SM00304 181 233 4.2E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS18575 a2e6018bd7cdbf74894f3c458a24d80c 453 SUPERFAMILY SSF55874 325 451 1.3E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS18575 a2e6018bd7cdbf74894f3c458a24d80c 453 SMART SM00387 341 452 1.6E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS18575 a2e6018bd7cdbf74894f3c458a24d80c 453 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 342 451 4.5E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS18575 a2e6018bd7cdbf74894f3c458a24d80c 453 Pfam PF00512 His Kinase A (phospho-acceptor) domain 237 299 1.6E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS18575 a2e6018bd7cdbf74894f3c458a24d80c 453 SMART SM00388 234 301 9.8E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS18575 a2e6018bd7cdbf74894f3c458a24d80c 453 SUPERFAMILY SSF47384 217 299 1.35E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CU254_RS18575 a2e6018bd7cdbf74894f3c458a24d80c 453 PRINTS PR00344 Bacterial sensor protein C-terminal signature 394 404 2.6E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS18575 a2e6018bd7cdbf74894f3c458a24d80c 453 PRINTS PR00344 Bacterial sensor protein C-terminal signature 436 449 2.6E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS18575 a2e6018bd7cdbf74894f3c458a24d80c 453 PRINTS PR00344 Bacterial sensor protein C-terminal signature 376 390 2.6E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS18575 a2e6018bd7cdbf74894f3c458a24d80c 453 PRINTS PR00344 Bacterial sensor protein C-terminal signature 412 430 2.6E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS18575 a2e6018bd7cdbf74894f3c458a24d80c 453 Pfam PF00672 HAMP domain 181 229 1.3E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CU254_RS22520 3899923d26f49571ca0e3e6cec738137 332 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 12 317 6.0E-46 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CU254_RS22520 3899923d26f49571ca0e3e6cec738137 332 Gene3D G3DSA:3.40.50.1100 49 150 1.7E-32 T 28-03-2018 CU254_RS22520 3899923d26f49571ca0e3e6cec738137 332 TIGRFAM TIGR01274 ACC_deam: 1-aminocyclopropane-1-carboxylate deaminase 4 330 1.4E-158 T 28-03-2018 IPR005965 1-aminocyclopropane-1-carboxylate deaminase GO:0008660|GO:0009310|GO:0030170 KEGG: 00270+3.5.99.7 CU254_RS22520 3899923d26f49571ca0e3e6cec738137 332 PIRSF PIRSF006278 1 332 2.9E-116 T 28-03-2018 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase CU254_RS22520 3899923d26f49571ca0e3e6cec738137 332 Gene3D G3DSA:3.40.50.1100 151 332 4.2E-30 T 28-03-2018 CU254_RS22520 3899923d26f49571ca0e3e6cec738137 332 SUPERFAMILY SSF53686 4 330 4.53E-96 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CU254_RS32850 88801efa5e07e89313a991f0ea85d99c 406 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 10 339 4.6E-47 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CU254_RS32850 88801efa5e07e89313a991f0ea85d99c 406 SUPERFAMILY SSF51395 5 354 8.93E-93 T 28-03-2018 CU254_RS32850 88801efa5e07e89313a991f0ea85d99c 406 Gene3D G3DSA:3.20.20.70 4 376 2.1E-100 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS09935 d89f05ea3b8ba8caea58ac156d503f1c 451 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 150 395 1.3E-68 T 28-03-2018 IPR024516 Mammalian cell entry, C-terminal CU254_RS09935 d89f05ea3b8ba8caea58ac156d503f1c 451 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 18 298 1.7E-55 T 28-03-2018 IPR005693 Virulence factor Mce protein CU254_RS09935 d89f05ea3b8ba8caea58ac156d503f1c 451 Pfam PF02470 MlaD protein 45 118 3.8E-10 T 28-03-2018 IPR003399 Mce/MlaD CU254_RS33565 5cbaa98713986f563443b54a8f7692ba 368 Gene3D G3DSA:1.10.530.10 97 325 1.6E-26 T 28-03-2018 CU254_RS33565 5cbaa98713986f563443b54a8f7692ba 368 SUPERFAMILY SSF53955 57 260 1.01E-34 T 28-03-2018 IPR023346 Lysozyme-like domain CU254_RS33565 5cbaa98713986f563443b54a8f7692ba 368 Pfam PF13406 Transglycosylase SLT domain 180 225 7.9E-7 T 28-03-2018 IPR031304 Transglycosylase SLT domain 2 CU254_RS30445 433e2408424c59ecee30606647ed72f8 399 SUPERFAMILY SSF51905 264 364 9.02E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS30445 433e2408424c59ecee30606647ed72f8 399 SUPERFAMILY SSF51905 5 165 9.02E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS30445 433e2408424c59ecee30606647ed72f8 399 Gene3D G3DSA:3.50.50.60 2 381 8.2E-34 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS30445 433e2408424c59ecee30606647ed72f8 399 Pfam PF01494 FAD binding domain 5 319 1.6E-19 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CU254_RS30445 433e2408424c59ecee30606647ed72f8 399 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 5.9E-11 T 28-03-2018 CU254_RS30445 433e2408424c59ecee30606647ed72f8 399 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 144 159 5.9E-11 T 28-03-2018 CU254_RS30445 433e2408424c59ecee30606647ed72f8 399 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 277 292 5.9E-11 T 28-03-2018 CU254_RS41985 b99fb24ba54ce70c4af2d118c40c7cd5 110 SUPERFAMILY SSF47413 26 89 2.52E-9 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS41985 b99fb24ba54ce70c4af2d118c40c7cd5 110 Pfam PF13560 Helix-turn-helix domain 27 86 9.6E-10 T 28-03-2018 CU254_RS41985 b99fb24ba54ce70c4af2d118c40c7cd5 110 SMART SM00530 30 86 5.0E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS41985 b99fb24ba54ce70c4af2d118c40c7cd5 110 Gene3D G3DSA:1.10.260.40 18 92 1.6E-12 T 28-03-2018 CU254_RS19115 e759874488bd59d6d582c6b969166b82 267 SUPERFAMILY SSF53474 5 264 5.52E-30 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS19115 e759874488bd59d6d582c6b969166b82 267 Pfam PF00561 alpha/beta hydrolase fold 22 124 1.6E-11 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS19115 e759874488bd59d6d582c6b969166b82 267 Gene3D G3DSA:3.40.50.1820 3 267 1.9E-31 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS15620 93a1fa6731304760ca05f3e27d400be9 145 Gene3D G3DSA:3.30.565.10 15 144 1.3E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS15620 93a1fa6731304760ca05f3e27d400be9 145 Pfam PF13581 Histidine kinase-like ATPase domain 28 129 2.5E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS15620 93a1fa6731304760ca05f3e27d400be9 145 SUPERFAMILY SSF55874 42 131 4.75E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS31565 ed27ef20e3434f1fb5261e7ec541529f 311 Gene3D G3DSA:1.10.260.40 17 89 4.6E-7 T 28-03-2018 CU254_RS27765 30a51210320093cafe2bd6d5a35a7711 711 Gene3D G3DSA:2.60.120.430 568 688 2.5E-4 T 28-03-2018 CU254_RS27765 30a51210320093cafe2bd6d5a35a7711 711 Pfam PF05506 Domain of unknown function (DUF756) 519 606 4.5E-17 T 28-03-2018 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 CU254_RS27765 30a51210320093cafe2bd6d5a35a7711 711 Pfam PF05506 Domain of unknown function (DUF756) 628 696 1.9E-6 T 28-03-2018 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 CU254_RS27765 30a51210320093cafe2bd6d5a35a7711 711 SUPERFAMILY SSF53649 166 359 3.92E-5 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CU254_RS27765 30a51210320093cafe2bd6d5a35a7711 711 SUPERFAMILY SSF53649 401 457 3.92E-5 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CU254_RS27765 30a51210320093cafe2bd6d5a35a7711 711 TIGRFAM TIGR03396 PC_PLC: phospholipase C, phosphocholine-specific 5 708 6.8E-244 T 28-03-2018 IPR017767 Bacterial phospholipase C, phosphocholine-specific GO:0034480 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 CU254_RS27765 30a51210320093cafe2bd6d5a35a7711 711 Pfam PF04185 Phosphoesterase family 48 457 1.4E-105 T 28-03-2018 IPR007312 Phosphoesterase GO:0016788 CU254_RS27765 30a51210320093cafe2bd6d5a35a7711 711 Gene3D G3DSA:3.40.720.10 143 462 1.6E-25 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CU254_RS27765 30a51210320093cafe2bd6d5a35a7711 711 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 4 28 0.0015 T 28-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal CU254_RS39705 1ae7a90c0e97624bc96e26e3b308e643 154 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 73 93 4.6E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS39705 1ae7a90c0e97624bc96e26e3b308e643 154 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 50 4.6E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS39705 1ae7a90c0e97624bc96e26e3b308e643 154 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 50 63 4.6E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS39705 1ae7a90c0e97624bc96e26e3b308e643 154 SUPERFAMILY SSF46955 39 150 3.63E-28 T 28-03-2018 IPR009061 Putative DNA-binding domain CU254_RS39705 1ae7a90c0e97624bc96e26e3b308e643 154 Gene3D G3DSA:1.10.1660.10 34 91 1.0E-18 T 28-03-2018 CU254_RS39705 1ae7a90c0e97624bc96e26e3b308e643 154 SMART SM00422 38 106 8.8E-15 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS39705 1ae7a90c0e97624bc96e26e3b308e643 154 Pfam PF13411 MerR HTH family regulatory protein 40 104 1.7E-14 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS39705 1ae7a90c0e97624bc96e26e3b308e643 154 Gene3D G3DSA:1.10.1660.10 92 153 2.6E-14 T 28-03-2018 CU254_RS06585 2196a9dd63318a22e81373019bc0a55a 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 116 132 8.5E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS06585 2196a9dd63318a22e81373019bc0a55a 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 201 221 8.5E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS06585 2196a9dd63318a22e81373019bc0a55a 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 71 82 8.5E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS06585 2196a9dd63318a22e81373019bc0a55a 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 180 8.5E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS06585 2196a9dd63318a22e81373019bc0a55a 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 142 161 8.5E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS06585 2196a9dd63318a22e81373019bc0a55a 240 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 129 157 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS06585 2196a9dd63318a22e81373019bc0a55a 240 SUPERFAMILY SSF51735 32 236 5.2E-60 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS06585 2196a9dd63318a22e81373019bc0a55a 240 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 38 236 4.7E-54 T 28-03-2018 CU254_RS06585 2196a9dd63318a22e81373019bc0a55a 240 Gene3D G3DSA:3.40.50.720 4 239 3.6E-60 T 28-03-2018 CU254_RS32365 65c6b417ebd413de25f861a993bc852d 318 Gene3D G3DSA:3.60.15.10 25 305 3.8E-46 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS32365 65c6b417ebd413de25f861a993bc852d 318 SUPERFAMILY SSF56281 78 301 7.86E-37 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS32365 65c6b417ebd413de25f861a993bc852d 318 Pfam PF00753 Metallo-beta-lactamase superfamily 82 293 6.7E-25 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS32365 65c6b417ebd413de25f861a993bc852d 318 SMART SM00849 79 293 4.6E-20 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS01315 56f8a3166bfe93723be57302a5345956 367 Pfam PF13579 Glycosyl transferase 4-like domain 15 175 1.0E-13 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CU254_RS01315 56f8a3166bfe93723be57302a5345956 367 SUPERFAMILY SSF53756 1 364 3.93E-61 T 28-03-2018 CU254_RS01315 56f8a3166bfe93723be57302a5345956 367 Gene3D G3DSA:3.40.50.2000 3 189 4.0E-12 T 28-03-2018 CU254_RS01315 56f8a3166bfe93723be57302a5345956 367 Gene3D G3DSA:3.40.50.2000 190 351 1.5E-36 T 28-03-2018 CU254_RS01315 56f8a3166bfe93723be57302a5345956 367 Pfam PF00534 Glycosyl transferases group 1 197 349 8.9E-26 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CU254_RS18705 16b444ca554988f4a7fb33745a4aa881 276 Gene3D G3DSA:3.20.20.360 2 249 1.6E-43 T 28-03-2018 CU254_RS18705 16b444ca554988f4a7fb33745a4aa881 276 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 14 215 2.9E-30 T 28-03-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 CU254_RS18705 16b444ca554988f4a7fb33745a4aa881 276 PIRSF PIRSF015582 2 276 3.6E-70 T 28-03-2018 IPR011206 Citrate lyase beta subunit-like CU254_RS18705 16b444ca554988f4a7fb33745a4aa881 276 SUPERFAMILY SSF51621 14 224 3.11E-52 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CU254_RS19740 6ff9291de2d200d2b58d94004480df5b 301 Gene3D G3DSA:3.40.50.1980 121 286 6.8E-38 T 28-03-2018 CU254_RS19740 6ff9291de2d200d2b58d94004480df5b 301 Pfam PF01497 Periplasmic binding protein 3 261 1.0E-16 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CU254_RS19740 6ff9291de2d200d2b58d94004480df5b 301 Gene3D G3DSA:3.40.50.1980 1 120 8.6E-21 T 28-03-2018 CU254_RS19740 6ff9291de2d200d2b58d94004480df5b 301 SUPERFAMILY SSF53807 2 285 3.49E-46 T 28-03-2018 CU254_RS13195 4e30c27222f84a30b68d50f97b2d0a84 277 Pfam PF01678 Diaminopimelate epimerase 148 262 9.7E-20 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CU254_RS13195 4e30c27222f84a30b68d50f97b2d0a84 277 Pfam PF01678 Diaminopimelate epimerase 1 107 1.3E-15 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CU254_RS13195 4e30c27222f84a30b68d50f97b2d0a84 277 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 1 267 2.5E-58 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CU254_RS13195 4e30c27222f84a30b68d50f97b2d0a84 277 SUPERFAMILY SSF54506 138 267 1.1E-38 T 28-03-2018 CU254_RS13195 4e30c27222f84a30b68d50f97b2d0a84 277 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 1 270 28.205 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CU254_RS13195 4e30c27222f84a30b68d50f97b2d0a84 277 Gene3D G3DSA:3.10.310.10 120 257 1.9E-36 T 28-03-2018 CU254_RS13195 4e30c27222f84a30b68d50f97b2d0a84 277 Gene3D G3DSA:3.10.310.10 1 119 2.3E-30 T 28-03-2018 CU254_RS13195 4e30c27222f84a30b68d50f97b2d0a84 277 SUPERFAMILY SSF54506 1 124 3.45E-27 T 28-03-2018 CU254_RS09110 e1b0db0862c880ec90249e11606b596e 458 Pfam PF08817 WXG100 protein secretion system (Wss), protein YukD 12 85 2.7E-20 T 28-03-2018 IPR024962 YukD-like CU254_RS09110 e1b0db0862c880ec90249e11606b596e 458 TIGRFAM TIGR03920 T7SS_EccD: type VII secretion integral membrane protein EccD 13 456 1.1E-53 T 28-03-2018 IPR006707 Type VII secretion system membrane protein EccD CU254_RS09110 e1b0db0862c880ec90249e11606b596e 458 PIRSF PIRSF017804 3 458 1.1E-57 T 28-03-2018 IPR006707 Type VII secretion system membrane protein EccD CU254_RS11495 560ca9a20ef466230818969faa0051e4 280 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 19 263 1.2E-35 T 28-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CU254_RS11495 560ca9a20ef466230818969faa0051e4 280 SUPERFAMILY SSF51366 5 270 5.18E-60 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CU254_RS11495 560ca9a20ef466230818969faa0051e4 280 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 92 105 - T 28-03-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CU254_RS11495 560ca9a20ef466230818969faa0051e4 280 Gene3D G3DSA:3.20.20.70 4 275 9.0E-80 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS11495 560ca9a20ef466230818969faa0051e4 280 TIGRFAM TIGR02127 pyrF_sub2: orotidine 5'-phosphate decarboxylase 5 264 6.9E-80 T 28-03-2018 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CU254_RS11495 560ca9a20ef466230818969faa0051e4 280 SMART SM00934 18 264 1.9E-24 T 28-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CU254_RS18230 83ea04c7ad80874d19b1fabcb3637b9b 64 Pfam PF05639 Pup-like protein 18 64 5.0E-21 T 28-03-2018 IPR008515 Ubiquitin-like, Pup CU254_RS18230 83ea04c7ad80874d19b1fabcb3637b9b 64 TIGRFAM TIGR03687 pupylate_cterm: ubiquitin-like protein Pup 33 64 1.5E-20 T 28-03-2018 IPR008515 Ubiquitin-like, Pup CU254_RS18230 83ea04c7ad80874d19b1fabcb3637b9b 64 Hamap MF_02106 Prokaryotic ubiquitin-like protein Pup [pup]. 1 64 15.941 T 28-03-2018 IPR008515 Ubiquitin-like, Pup CU254_RS34660 893dca63bf10ebe6ad6cc355dd651744 146 SUPERFAMILY SSF55729 2 144 6.91E-23 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS34660 893dca63bf10ebe6ad6cc355dd651744 146 Pfam PF00583 Acetyltransferase (GNAT) family 41 132 1.1E-10 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS34660 893dca63bf10ebe6ad6cc355dd651744 146 Gene3D G3DSA:3.40.630.30 1 146 5.3E-22 T 28-03-2018 CU254_RS13260 17352f876b7aee76e9e75fa2f53b8391 1174 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 4 1058 0.0 T 28-03-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CU254_RS13260 17352f876b7aee76e9e75fa2f53b8391 1174 Gene3D G3DSA:1.10.150.280 813 919 1.3E-8 T 28-03-2018 CU254_RS13260 17352f876b7aee76e9e75fa2f53b8391 1174 Pfam PF14579 Helix-hairpin-helix motif 834 920 4.6E-26 T 28-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CU254_RS13260 17352f876b7aee76e9e75fa2f53b8391 1174 SUPERFAMILY SSF89550 125 274 2.94E-29 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CU254_RS13260 17352f876b7aee76e9e75fa2f53b8391 1174 SUPERFAMILY SSF89550 4 89 2.94E-29 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CU254_RS13260 17352f876b7aee76e9e75fa2f53b8391 1174 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 320 761 1.8E-159 T 28-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CU254_RS13260 17352f876b7aee76e9e75fa2f53b8391 1174 Gene3D G3DSA:2.40.50.140 1000 1092 3.0E-10 T 28-03-2018 CU254_RS13260 17352f876b7aee76e9e75fa2f53b8391 1174 SMART SM00481 5 72 1.4E-31 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CU254_RS13260 17352f876b7aee76e9e75fa2f53b8391 1174 Gene3D G3DSA:3.20.20.140 2 274 2.3E-47 T 28-03-2018 CU254_RS13260 17352f876b7aee76e9e75fa2f53b8391 1174 Pfam PF02811 PHP domain 6 198 6.8E-47 T 28-03-2018 IPR004013 PHP domain GO:0003824 CU254_RS08525 794a503bf4716f372d6160910440f9e6 456 Gene3D G3DSA:3.30.390.30 331 454 5.7E-24 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CU254_RS08525 794a503bf4716f372d6160910440f9e6 456 Gene3D G3DSA:3.50.50.60 1 149 1.1E-20 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS08525 794a503bf4716f372d6160910440f9e6 456 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 124 142 1.5E-13 T 28-03-2018 CU254_RS08525 794a503bf4716f372d6160910440f9e6 456 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 247 263 1.5E-13 T 28-03-2018 CU254_RS08525 794a503bf4716f372d6160910440f9e6 456 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 277 299 1.5E-13 T 28-03-2018 CU254_RS08525 794a503bf4716f372d6160910440f9e6 456 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 163 181 1.5E-13 T 28-03-2018 CU254_RS08525 794a503bf4716f372d6160910440f9e6 456 SUPERFAMILY SSF55424 341 453 1.15E-21 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CU254_RS08525 794a503bf4716f372d6160910440f9e6 456 Gene3D G3DSA:3.50.50.60 198 330 1.3E-14 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS08525 794a503bf4716f372d6160910440f9e6 456 Gene3D G3DSA:3.50.50.60 150 197 3.3E-9 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS08525 794a503bf4716f372d6160910440f9e6 456 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 345 447 1.6E-16 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CU254_RS08525 794a503bf4716f372d6160910440f9e6 456 PIRSF PIRSF000350 1 450 8.2E-55 T 28-03-2018 CU254_RS08525 794a503bf4716f372d6160910440f9e6 456 SUPERFAMILY SSF51905 1 321 2.25E-39 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS08525 794a503bf4716f372d6160910440f9e6 456 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 127 136 8.9E-44 T 28-03-2018 CU254_RS08525 794a503bf4716f372d6160910440f9e6 456 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 292 299 8.9E-44 T 28-03-2018 CU254_RS08525 794a503bf4716f372d6160910440f9e6 456 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 341 362 8.9E-44 T 28-03-2018 CU254_RS08525 794a503bf4716f372d6160910440f9e6 456 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 31 46 8.9E-44 T 28-03-2018 CU254_RS08525 794a503bf4716f372d6160910440f9e6 456 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 248 262 8.9E-44 T 28-03-2018 CU254_RS08525 794a503bf4716f372d6160910440f9e6 456 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 163 188 8.9E-44 T 28-03-2018 CU254_RS08525 794a503bf4716f372d6160910440f9e6 456 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 403 418 8.9E-44 T 28-03-2018 CU254_RS08525 794a503bf4716f372d6160910440f9e6 456 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 1 300 1.3E-46 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS08715 0afca6e189c85baf305a3e4844cc7947 314 Pfam PF00106 short chain dehydrogenase 17 220 3.7E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS08715 0afca6e189c85baf305a3e4844cc7947 314 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 17 34 2.0E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS08715 0afca6e189c85baf305a3e4844cc7947 314 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 139 155 2.0E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS08715 0afca6e189c85baf305a3e4844cc7947 314 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 94 105 2.0E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS08715 0afca6e189c85baf305a3e4844cc7947 314 SUPERFAMILY SSF51735 11 309 2.42E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS08715 0afca6e189c85baf305a3e4844cc7947 314 Gene3D G3DSA:3.40.50.720 1 312 1.4E-54 T 28-03-2018 CU254_RS16045 4859b1a3e76d5a769d7ca5d09258db4a 432 Pfam PF00027 Cyclic nucleotide-binding domain 79 160 3.3E-10 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CU254_RS16045 4859b1a3e76d5a769d7ca5d09258db4a 432 Gene3D G3DSA:2.60.120.10 51 189 9.2E-17 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS16045 4859b1a3e76d5a769d7ca5d09258db4a 432 SUPERFAMILY SSF51206 54 180 1.7E-16 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like CU254_RS37845 96f245f738fd5fda27ae9c25e8f46b89 169 SUPERFAMILY SSF88946 3 92 1.1E-14 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS37845 96f245f738fd5fda27ae9c25e8f46b89 169 Gene3D G3DSA:1.10.1740.10 1 93 4.3E-15 T 28-03-2018 CU254_RS37845 96f245f738fd5fda27ae9c25e8f46b89 169 Gene3D G3DSA:1.10.10.10 98 167 1.1E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS37845 96f245f738fd5fda27ae9c25e8f46b89 169 Pfam PF08281 Sigma-70, region 4 104 157 6.3E-13 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS37845 96f245f738fd5fda27ae9c25e8f46b89 169 SUPERFAMILY SSF88659 99 162 1.83E-13 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS37845 96f245f738fd5fda27ae9c25e8f46b89 169 Pfam PF04542 Sigma-70 region 2 17 79 1.4E-9 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS37845 96f245f738fd5fda27ae9c25e8f46b89 169 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 3 163 1.5E-47 T 28-03-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 CU254_RS37845 96f245f738fd5fda27ae9c25e8f46b89 169 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 9 160 6.8E-22 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS20100 8e6ab1bd5905820af886f1eaddb59492 483 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 34 328 4.0E-66 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CU254_RS20100 8e6ab1bd5905820af886f1eaddb59492 483 Gene3D G3DSA:3.20.20.300 11 330 2.8E-82 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CU254_RS20100 8e6ab1bd5905820af886f1eaddb59492 483 SUPERFAMILY SSF51445 14 327 1.02E-75 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS20100 8e6ab1bd5905820af886f1eaddb59492 483 PRINTS PR00133 Glycosyl hydrolase family 3 signature 134 150 2.8E-7 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CU254_RS20100 8e6ab1bd5905820af886f1eaddb59492 483 PRINTS PR00133 Glycosyl hydrolase family 3 signature 240 258 2.8E-7 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CU254_RS20100 8e6ab1bd5905820af886f1eaddb59492 483 PRINTS PR00133 Glycosyl hydrolase family 3 signature 165 181 2.8E-7 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CU254_RS20100 8e6ab1bd5905820af886f1eaddb59492 483 PRINTS PR00133 Glycosyl hydrolase family 3 signature 87 106 2.8E-7 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CU254_RS21190 a710036857446b5c72903f7f3bd160a8 137 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 6 131 3.4E-12 T 28-03-2018 IPR028973 PhnB-like CU254_RS21190 a710036857446b5c72903f7f3bd160a8 137 Gene3D G3DSA:3.10.180.10 1 136 2.5E-25 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS21190 a710036857446b5c72903f7f3bd160a8 137 SUPERFAMILY SSF54593 3 132 2.63E-33 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS13385 96761d022e96de3d56fe5831141330b3 211 Pfam PF01810 LysE type translocator 24 208 5.7E-40 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CU254_RS32860 4200431dcd9ad637cfd2f9c40bdd2f96 155 SUPERFAMILY SSF140663 29 139 8.11E-30 T 28-03-2018 IPR023203 TTHA0068-like domain CU254_RS32860 4200431dcd9ad637cfd2f9c40bdd2f96 155 Pfam PF03745 Domain of unknown function (DUF309) 47 104 2.9E-20 T 28-03-2018 IPR005500 Protein of unknown function DUF309 CU254_RS32860 4200431dcd9ad637cfd2f9c40bdd2f96 155 Gene3D G3DSA:1.10.3450.10 1 151 1.8E-46 T 28-03-2018 IPR023203 TTHA0068-like domain CU254_RS42255 a13f36b4efca6ef2a9750c36e8768647 587 Gene3D G3DSA:3.40.50.300 162 559 3.2E-18 T 28-03-2018 CU254_RS42255 a13f36b4efca6ef2a9750c36e8768647 587 Pfam PF02534 Type IV secretory system Conjugative DNA transfer 151 278 8.0E-10 T 28-03-2018 IPR003688 Type IV secretion system protein TraG/VirD4 GO:0009291|GO:0016020 CU254_RS42255 a13f36b4efca6ef2a9750c36e8768647 587 SUPERFAMILY SSF52540 136 558 8.5E-32 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS42255 a13f36b4efca6ef2a9750c36e8768647 587 Pfam PF12696 TraM recognition site of TraD and TraG 414 533 1.7E-24 T 28-03-2018 IPR032689 TraD/TraG, TraM recognition site CU254_RS11780 2b3d2a523a10a52d7ecb8eb4ed684a6e 323 Pfam PF02628 Cytochrome oxidase assembly protein 27 294 3.1E-10 T 28-03-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 CU254_RS26150 545248fc8a13916c9a13c7eba8e67acf 88 Gene3D G3DSA:3.30.1450.10 10 88 8.4E-9 T 28-03-2018 CU254_RS26150 545248fc8a13916c9a13c7eba8e67acf 88 Pfam PF11006 Protein of unknown function (DUF2845) 11 82 1.1E-6 T 28-03-2018 IPR021268 Protein of unknown function DUF2845 CU254_RS13655 af79bebb5683c6b2a3385a901b453478 197 Pfam PF03729 Short repeat of unknown function (DUF308) 26 94 2.2E-11 T 28-03-2018 IPR005325 Protein of unknown function DUF308, membrane CU254_RS13655 af79bebb5683c6b2a3385a901b453478 197 Pfam PF03729 Short repeat of unknown function (DUF308) 81 152 1.7E-13 T 28-03-2018 IPR005325 Protein of unknown function DUF308, membrane CU254_RS13655 af79bebb5683c6b2a3385a901b453478 197 Pfam PF03729 Short repeat of unknown function (DUF308) 138 186 3.1E-5 T 28-03-2018 IPR005325 Protein of unknown function DUF308, membrane CU254_RS14920 661075d8e6302018c9dbd19a889be02d 217 Pfam PF01177 Asp/Glu/Hydantoin racemase 1 202 7.0E-44 T 28-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CU254_RS14920 661075d8e6302018c9dbd19a889be02d 217 SUPERFAMILY SSF53681 108 204 3.49E-11 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CU254_RS14920 661075d8e6302018c9dbd19a889be02d 217 TIGRFAM TIGR00035 asp_race: aspartate racemase 1 205 1.0E-42 T 28-03-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 CU254_RS14920 661075d8e6302018c9dbd19a889be02d 217 SUPERFAMILY SSF53681 1 102 5.43E-23 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CU254_RS14920 661075d8e6302018c9dbd19a889be02d 217 Gene3D G3DSA:3.40.50.1860 1 107 3.7E-31 T 28-03-2018 CU254_RS14920 661075d8e6302018c9dbd19a889be02d 217 Gene3D G3DSA:3.40.50.1860 108 198 8.3E-13 T 28-03-2018 CU254_RS25370 2d7d4d460a57533862a22a0d429cc4c8 446 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 38 374 1.8E-15 T 28-03-2018 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 CU254_RS05510 62c077720a9f574c08842f85f1a22c1a 102 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 6 96 1.9E-10 T 28-03-2018 IPR022536 ESX-1 secretion-associated protein EspC GO:0009306 CU254_RS05510 62c077720a9f574c08842f85f1a22c1a 102 Gene3D G3DSA:1.10.287.1060 1 98 1.9E-12 T 28-03-2018 CU254_RS24225 dc56f807ea5861aacbfc6e505f34ce46 395 Gene3D G3DSA:3.40.50.10540 1 392 1.7E-121 T 28-03-2018 IPR023606 CoA-transferase family III domain CU254_RS24225 dc56f807ea5861aacbfc6e505f34ce46 395 Pfam PF02515 CoA-transferase family III 7 371 2.9E-115 T 28-03-2018 IPR003673 CoA-transferase family III GO:0003824 CU254_RS24225 dc56f807ea5861aacbfc6e505f34ce46 395 SUPERFAMILY SSF89796 5 385 1.44E-116 T 28-03-2018 IPR023606 CoA-transferase family III domain CU254_RS03915 b837e6ac3eaed5ddc7b6523ee5e252a1 290 SMART SM00481 6 70 3.0E-15 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CU254_RS03915 b837e6ac3eaed5ddc7b6523ee5e252a1 290 Gene3D G3DSA:3.20.20.140 1 264 8.1E-48 T 28-03-2018 CU254_RS03915 b837e6ac3eaed5ddc7b6523ee5e252a1 290 SUPERFAMILY SSF89550 2 89 3.14E-43 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CU254_RS03915 b837e6ac3eaed5ddc7b6523ee5e252a1 290 SUPERFAMILY SSF89550 172 263 3.14E-43 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CU254_RS03915 b837e6ac3eaed5ddc7b6523ee5e252a1 290 Pfam PF02811 PHP domain 7 172 4.9E-7 T 28-03-2018 IPR004013 PHP domain GO:0003824 CU254_RS03995 8ff5ec5c4ee2ffff99881adb648a88aa 387 Pfam PF11350 Protein of unknown function (DUF3152) 170 382 5.8E-70 T 28-03-2018 IPR022603 Domain of unknown function DUF3152 CU254_RS03995 8ff5ec5c4ee2ffff99881adb648a88aa 387 SUPERFAMILY SSF55486 160 347 9.65E-13 T 28-03-2018 CU254_RS03995 8ff5ec5c4ee2ffff99881adb648a88aa 387 Gene3D G3DSA:3.40.390.10 156 367 6.3E-5 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CU254_RS17315 47e36412a24cbcca56c57022b3d9abe8 212 Gene3D G3DSA:2.130.10.10 118 210 3.0E-9 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CU254_RS17315 47e36412a24cbcca56c57022b3d9abe8 212 Gene3D G3DSA:2.130.10.10 6 117 6.1E-5 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CU254_RS17315 47e36412a24cbcca56c57022b3d9abe8 212 SUPERFAMILY SSF50969 18 204 3.81E-16 T 28-03-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like CU254_RS01780 9997f5596d005ca0cb9e9a18fbafa048 342 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 11 295 9.1E-69 T 28-03-2018 IPR005693 Virulence factor Mce protein CU254_RS01780 9997f5596d005ca0cb9e9a18fbafa048 342 Pfam PF02470 MlaD protein 39 110 2.5E-16 T 28-03-2018 IPR003399 Mce/MlaD CU254_RS02275 ff75f2d44c185a0ea311c71c7a036b40 552 Pfam PF09972 Predicted membrane protein (DUF2207) 45 500 7.2E-37 T 28-03-2018 IPR018702 Protein of unknown function DUF2207, membrane CU254_RS15275 bc65f250d46fae906c392ff3977dd758 246 SUPERFAMILY SSF46785 16 101 1.15E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS15275 bc65f250d46fae906c392ff3977dd758 246 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 79 5.1E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS15275 bc65f250d46fae906c392ff3977dd758 246 Gene3D G3DSA:1.20.120.530 90 245 1.2E-17 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS15275 bc65f250d46fae906c392ff3977dd758 246 Pfam PF07729 FCD domain 109 236 1.6E-16 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS15275 bc65f250d46fae906c392ff3977dd758 246 SUPERFAMILY SSF48008 108 242 1.57E-15 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS15275 bc65f250d46fae906c392ff3977dd758 246 SMART SM00895 109 237 9.2E-13 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS15275 bc65f250d46fae906c392ff3977dd758 246 Gene3D G3DSA:1.10.10.10 6 87 1.1E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS10370 cd878f3077eed5242daba3cac8cc50d4 180 SUPERFAMILY SSF52980 4 174 1.98E-29 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CU254_RS10370 cd878f3077eed5242daba3cac8cc50d4 180 Pfam PF05685 Putative restriction endonuclease 17 162 2.9E-27 T 28-03-2018 IPR008538 Domain of unknown function DUF820 CU254_RS10370 cd878f3077eed5242daba3cac8cc50d4 180 Gene3D G3DSA:3.90.1570.10 1 175 7.1E-35 T 28-03-2018 CU254_RS04810 8693863a50fac16cf098f9e46e9ed18b 373 SMART SM00228 156 220 2.8E-5 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CU254_RS04810 8693863a50fac16cf098f9e46e9ed18b 373 Pfam PF13180 PDZ domain 164 230 2.1E-10 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CU254_RS04810 8693863a50fac16cf098f9e46e9ed18b 373 Gene3D G3DSA:3.30.230.10 69 372 1.2E-42 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CU254_RS04810 8693863a50fac16cf098f9e46e9ed18b 373 SUPERFAMILY SSF50156 162 265 1.71E-16 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CU254_RS04810 8693863a50fac16cf098f9e46e9ed18b 373 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 264 360 1.7E-10 T 28-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 CU254_RS04810 8693863a50fac16cf098f9e46e9ed18b 373 SUPERFAMILY SSF54211 251 361 6.83E-21 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CU254_RS20655 be28b25dd7df86c4206433bd8e6dc37d 327 Gene3D G3DSA:3.40.50.970 3 196 1.5E-55 T 28-03-2018 CU254_RS20655 be28b25dd7df86c4206433bd8e6dc37d 327 SUPERFAMILY SSF52518 5 188 3.16E-58 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS20655 be28b25dd7df86c4206433bd8e6dc37d 327 Pfam PF02780 Transketolase, C-terminal domain 196 316 1.5E-32 T 28-03-2018 IPR033248 Transketolase, C-terminal domain CU254_RS20655 be28b25dd7df86c4206433bd8e6dc37d 327 Gene3D G3DSA:3.40.50.920 197 326 1.5E-34 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CU254_RS20655 be28b25dd7df86c4206433bd8e6dc37d 327 SMART SM00861 7 181 8.9E-48 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CU254_RS20655 be28b25dd7df86c4206433bd8e6dc37d 327 SUPERFAMILY SSF52922 194 325 1.57E-36 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CU254_RS20655 be28b25dd7df86c4206433bd8e6dc37d 327 Pfam PF02779 Transketolase, pyrimidine binding domain 6 180 4.3E-41 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CU254_RS08005 323d6cfe8836cf5f14bfbba80f4efe97 107 Pfam PF10611 Protein of unknown function (DUF2469) 1 100 1.8E-53 T 28-03-2018 IPR019592 Protein of unknown function DUF2469 CU254_RS34755 55f2fa6d3276a0eead9d88826a6f3a16 185 Gene3D G3DSA:3.10.490.10 7 174 1.4E-6 T 28-03-2018 CU254_RS13570 cb35eea11d701302b194289c9098afa3 179 SUPERFAMILY SSF82607 6 74 9.02E-6 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CU254_RS13570 cb35eea11d701302b194289c9098afa3 179 Pfam PF02575 YbaB/EbfC DNA-binding family 6 78 1.0E-8 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CU254_RS13570 cb35eea11d701302b194289c9098afa3 179 Gene3D G3DSA:3.30.1310.10 4 81 2.3E-14 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CU254_RS11015 0e7015e83315b728ff255a70f49ec139 133 Gene3D G3DSA:3.40.50.1010 4 133 7.0E-16 T 28-03-2018 IPR029060 PIN domain-like CU254_RS11015 0e7015e83315b728ff255a70f49ec139 133 Pfam PF01850 PIN domain 8 118 6.7E-7 T 28-03-2018 IPR002716 PIN domain CU254_RS11015 0e7015e83315b728ff255a70f49ec139 133 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 7 131 9.442 T 28-03-2018 IPR022907 VapC family GO:0004540 CU254_RS11015 0e7015e83315b728ff255a70f49ec139 133 SUPERFAMILY SSF88723 6 127 3.36E-17 T 28-03-2018 IPR029060 PIN domain-like CU254_RS35145 66f59f457f2a472a6e1fdf841eb3b464 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 9.5E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS35145 66f59f457f2a472a6e1fdf841eb3b464 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 9.5E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS35145 66f59f457f2a472a6e1fdf841eb3b464 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 1.4E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS35145 66f59f457f2a472a6e1fdf841eb3b464 203 Gene3D G3DSA:1.10.10.60 2 43 2.8E-14 T 28-03-2018 CU254_RS35145 66f59f457f2a472a6e1fdf841eb3b464 203 SUPERFAMILY SSF46689 5 84 3.29E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS35145 66f59f457f2a472a6e1fdf841eb3b464 203 Gene3D G3DSA:1.10.260.40 44 65 2.8E-7 T 28-03-2018 CU254_RS35145 66f59f457f2a472a6e1fdf841eb3b464 203 Gene3D G3DSA:1.10.357.10 66 203 1.4E-6 T 28-03-2018 CU254_RS24085 599daafa47500022efe8399a4b3d95b6 119 Pfam PF04343 Protein of unknown function, DUF488 8 117 1.6E-30 T 28-03-2018 IPR007438 Protein of unknown function DUF488 CU254_RS18470 39a5833348447bd01e0d8e68f11c30d4 453 Pfam PF07969 Amidohydrolase family 100 445 9.4E-47 T 28-03-2018 IPR013108 Amidohydrolase 3 CU254_RS18470 39a5833348447bd01e0d8e68f11c30d4 453 SUPERFAMILY SSF51556 63 405 7.86E-25 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS18470 39a5833348447bd01e0d8e68f11c30d4 453 Gene3D G3DSA:3.20.20.140 389 446 0.0088 T 28-03-2018 CU254_RS18470 39a5833348447bd01e0d8e68f11c30d4 453 Gene3D G3DSA:2.30.40.10 2 90 1.2E-14 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS18470 39a5833348447bd01e0d8e68f11c30d4 453 Gene3D G3DSA:3.20.20.140 93 388 6.8E-36 T 28-03-2018 CU254_RS18470 39a5833348447bd01e0d8e68f11c30d4 453 SUPERFAMILY SSF51338 4 64 2.16E-21 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS18470 39a5833348447bd01e0d8e68f11c30d4 453 SUPERFAMILY SSF51338 404 450 2.16E-21 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS00810 cf398ef1ddec1a2d66ff8e6f9a6fca0b 194 SUPERFAMILY SSF109854 8 157 4.73E-33 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CU254_RS00810 cf398ef1ddec1a2d66ff8e6f9a6fca0b 194 Pfam PF04978 Protein of unknown function (DUF664) 10 158 9.1E-40 T 28-03-2018 IPR007061 Protein of unknown function DUF664 CU254_RS00810 cf398ef1ddec1a2d66ff8e6f9a6fca0b 194 Gene3D G3DSA:1.20.120.450 6 179 4.3E-28 T 28-03-2018 CU254_RS13870 f699847ad7ee71fc33569087631821c2 390 Pfam PF16483 Beta-1,3-glucanase 33 386 3.8E-113 T 28-03-2018 IPR032477 Beta-1,3-glucanase, N-terminal KEGG: 00500+3.2.1.39 CU254_RS31170 2e190740ebb51a76040398678b22fb88 179 Gene3D G3DSA:3.90.79.10 5 179 5.2E-34 T 28-03-2018 CU254_RS31170 2e190740ebb51a76040398678b22fb88 179 SUPERFAMILY SSF55811 5 176 1.08E-37 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CU254_RS31170 2e190740ebb51a76040398678b22fb88 179 Pfam PF00293 NUDIX domain 44 155 5.2E-12 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CU254_RS08580 f37b6abba8387aad615dc78ec9b71ef4 397 Pfam PF12698 ABC-2 family transporter protein 26 374 3.7E-49 T 28-03-2018 CU254_RS06945 1defb3318b91bf170c770f2a64d8a6ae 334 Gene3D G3DSA:3.40.50.1980 27 172 6.6E-24 T 28-03-2018 CU254_RS06945 1defb3318b91bf170c770f2a64d8a6ae 334 Pfam PF01497 Periplasmic binding protein 59 308 2.3E-25 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CU254_RS06945 1defb3318b91bf170c770f2a64d8a6ae 334 SUPERFAMILY SSF53807 50 329 1.14E-46 T 28-03-2018 CU254_RS06945 1defb3318b91bf170c770f2a64d8a6ae 334 Gene3D G3DSA:3.40.50.1980 173 332 1.6E-40 T 28-03-2018 CU254_RS04800 fa59a7817605578625424861f115ae66 169 Pfam PF01863 Protein of unknown function DUF45 87 144 4.5E-20 T 28-03-2018 IPR002725 Protein of unknown function DUF45 CU254_RS12810 4390c19967010e84def1fda984443a78 350 Gene3D G3DSA:1.10.3720.10 38 337 4.9E-40 T 28-03-2018 CU254_RS12810 4390c19967010e84def1fda984443a78 350 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 150 348 1.5E-33 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS12810 4390c19967010e84def1fda984443a78 350 SUPERFAMILY SSF161098 129 335 1.2E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS09760 a0ff105ed1776ad77633a16f3a9438e1 163 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 144 1.7E-47 T 28-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 CU254_RS09760 a0ff105ed1776ad77633a16f3a9438e1 163 Pfam PF03477 ATP cone domain 47 132 1.8E-13 T 28-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 CU254_RS09760 a0ff105ed1776ad77633a16f3a9438e1 163 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 150 76.921 T 28-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 CU254_RS12245 ef43e3f1f257ef75c089d9a73b35e877 460 ProSitePatterns PS00217 Sugar transport proteins signature 2. 126 151 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CU254_RS12245 ef43e3f1f257ef75c089d9a73b35e877 460 Gene3D G3DSA:1.20.1250.20 12 234 1.0E-36 T 28-03-2018 CU254_RS12245 ef43e3f1f257ef75c089d9a73b35e877 460 Gene3D G3DSA:1.20.1250.20 246 459 5.7E-37 T 28-03-2018 CU254_RS12245 ef43e3f1f257ef75c089d9a73b35e877 460 SUPERFAMILY SSF103473 16 458 2.09E-88 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS12245 ef43e3f1f257ef75c089d9a73b35e877 460 ProSitePatterns PS00216 Sugar transport proteins signature 1. 324 340 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CU254_RS12245 ef43e3f1f257ef75c089d9a73b35e877 460 Pfam PF00083 Sugar (and other) transporter 62 459 8.9E-47 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CU254_RS22220 965ccf72fe90480bb78d64120193245e 765 Gene3D G3DSA:2.60.40.1180 631 743 1.8E-15 T 28-03-2018 CU254_RS22220 965ccf72fe90480bb78d64120193245e 765 SUPERFAMILY SSF48208 249 696 5.89E-35 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CU254_RS22220 965ccf72fe90480bb78d64120193245e 765 Gene3D G3DSA:1.50.10.10 218 630 6.0E-55 T 28-03-2018 CU254_RS33730 719c24b18e8a02c2d213348378d90d1c 126 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 115 3.3E-5 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CU254_RS33730 719c24b18e8a02c2d213348378d90d1c 126 Gene3D G3DSA:3.10.180.10 1 123 9.9E-22 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS33730 719c24b18e8a02c2d213348378d90d1c 126 SUPERFAMILY SSF54593 3 117 3.03E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS02295 deb20daba7603d80bea165f9011fdb63 473 SUPERFAMILY SSF56801 5 472 1.7E-129 T 28-03-2018 CU254_RS02295 deb20daba7603d80bea165f9011fdb63 473 Pfam PF13193 AMP-binding enzyme C-terminal domain 392 466 1.5E-20 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS02295 deb20daba7603d80bea165f9011fdb63 473 Gene3D G3DSA:2.30.38.10 292 375 2.6E-29 T 28-03-2018 CU254_RS02295 deb20daba7603d80bea165f9011fdb63 473 Pfam PF00501 AMP-binding enzyme 12 382 1.8E-83 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS02295 deb20daba7603d80bea165f9011fdb63 473 Gene3D G3DSA:3.40.50.980 1 140 3.0E-28 T 28-03-2018 CU254_RS02295 deb20daba7603d80bea165f9011fdb63 473 Gene3D G3DSA:3.40.50.980 141 291 2.8E-42 T 28-03-2018 CU254_RS02295 deb20daba7603d80bea165f9011fdb63 473 ProSitePatterns PS00455 Putative AMP-binding domain signature. 135 146 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS02295 deb20daba7603d80bea165f9011fdb63 473 Gene3D G3DSA:3.30.300.30 378 473 1.4E-28 T 28-03-2018 CU254_RS34575 fbec6b6909a86fa99ecb84849e05bcac 282 Gene3D G3DSA:1.10.10.10 16 99 2.5E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS34575 fbec6b6909a86fa99ecb84849e05bcac 282 Pfam PF08223 PaaX-like protein C-terminal domain 181 277 6.1E-26 T 28-03-2018 IPR013225 PaaX-like, C-terminal CU254_RS34575 fbec6b6909a86fa99ecb84849e05bcac 282 PIRSF PIRSF020623 4 282 1.1E-78 T 28-03-2018 IPR011965 Phenylacetic acid degradation operon negative regulatory protein PaaX GO:0006351 CU254_RS34575 fbec6b6909a86fa99ecb84849e05bcac 282 Pfam PF07848 PaaX-like protein 19 85 2.4E-15 T 28-03-2018 IPR012906 PaaX-like, N-terminal CU254_RS05890 275b28054b7cbe6564ae5624720ac7bf 354 SUPERFAMILY SSF51621 74 352 4.4E-71 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CU254_RS05890 275b28054b7cbe6564ae5624720ac7bf 354 Pfam PF13714 Phosphoenolpyruvate phosphomutase 77 317 1.7E-58 T 28-03-2018 CU254_RS05890 275b28054b7cbe6564ae5624720ac7bf 354 Gene3D G3DSA:3.20.20.60 69 354 5.4E-64 T 28-03-2018 CU254_RS05170 ef3d228fc7f12eee5f4c51bd27a72a01 706 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 20 123 2.3E-10 T 28-03-2018 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV CU254_RS05170 ef3d228fc7f12eee5f4c51bd27a72a01 706 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 160 440 1.1E-7 T 28-03-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 CU254_RS05170 ef3d228fc7f12eee5f4c51bd27a72a01 706 SUPERFAMILY SSF53649 289 437 9.76E-16 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CU254_RS05170 ef3d228fc7f12eee5f4c51bd27a72a01 706 SUPERFAMILY SSF53649 156 238 9.76E-16 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CU254_RS05170 ef3d228fc7f12eee5f4c51bd27a72a01 706 Gene3D G3DSA:3.40.720.10 148 609 1.9E-16 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CU254_RS41505 bfe1f5cb1d4dbc7ceb4c2ab2fb2529be 153 Gene3D G3DSA:1.10.260.40 5 98 8.3E-9 T 28-03-2018 CU254_RS06695 c16a930a25b9560af67f98a65079e520 509 Pfam PF09210 Domain of unknown function (DUF1957) 409 502 2.8E-21 T 28-03-2018 IPR015293 Domain of unknown function DUF1957 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 CU254_RS06695 c16a930a25b9560af67f98a65079e520 509 SUPERFAMILY SSF88688 388 506 1.14E-19 T 28-03-2018 IPR028995 Glycoside hydrolase families 57/38, central domain CU254_RS06695 c16a930a25b9560af67f98a65079e520 509 Gene3D G3DSA:1.20.1430.10 395 509 6.3E-28 T 28-03-2018 IPR015293 Domain of unknown function DUF1957 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 CU254_RS06695 c16a930a25b9560af67f98a65079e520 509 Pfam PF03065 Glycosyl hydrolase family 57 14 343 1.3E-20 T 28-03-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 CU254_RS06695 c16a930a25b9560af67f98a65079e520 509 SUPERFAMILY SSF88713 10 393 2.42E-88 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CU254_RS06695 c16a930a25b9560af67f98a65079e520 509 Gene3D G3DSA:3.20.110.10 7 393 1.8E-84 T 28-03-2018 IPR027291 Glycoside hydrolase 38/57, N-terminal domain CU254_RS03425 e86cd9e092d985428b0b76a9ddcaaf5f 558 Gene3D G3DSA:3.30.300.30 454 557 6.8E-25 T 28-03-2018 CU254_RS03425 e86cd9e092d985428b0b76a9ddcaaf5f 558 SUPERFAMILY SSF56801 16 555 2.62E-147 T 28-03-2018 CU254_RS03425 e86cd9e092d985428b0b76a9ddcaaf5f 558 Gene3D G3DSA:3.40.50.980 21 192 6.2E-38 T 28-03-2018 CU254_RS03425 e86cd9e092d985428b0b76a9ddcaaf5f 558 Gene3D G3DSA:3.40.50.980 193 368 1.3E-40 T 28-03-2018 CU254_RS03425 e86cd9e092d985428b0b76a9ddcaaf5f 558 Pfam PF00501 AMP-binding enzyme 31 458 1.4E-101 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS03425 e86cd9e092d985428b0b76a9ddcaaf5f 558 Gene3D G3DSA:2.30.38.10 369 453 4.3E-30 T 28-03-2018 CU254_RS03425 e86cd9e092d985428b0b76a9ddcaaf5f 558 Pfam PF13193 AMP-binding enzyme C-terminal domain 469 544 1.1E-14 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS03425 e86cd9e092d985428b0b76a9ddcaaf5f 558 ProSitePatterns PS00455 Putative AMP-binding domain signature. 186 197 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS07330 c7c5f0c58e516138aed0b06c3568f994 205 Pfam PF02620 Uncharacterized ACR, COG1399 76 185 4.5E-29 T 28-03-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD CU254_RS31410 df7b25c03ce2b417b5000bc17f8e838d 253 Pfam PF03713 Domain of unknown function (DUF305) 78 242 3.8E-47 T 28-03-2018 IPR005183 Domain of unknown function DUF305 CU254_RS31410 df7b25c03ce2b417b5000bc17f8e838d 253 Gene3D G3DSA:1.20.1260.10 70 246 9.2E-52 T 28-03-2018 IPR012347 Ferritin-related CU254_RS15635 72f08d97e5eb7c90938801cecedd235a 65 SMART SM00704 19 63 1.1E-8 T 28-03-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 CU254_RS15635 72f08d97e5eb7c90938801cecedd235a 65 Pfam PF09360 Iron-binding zinc finger CDGSH type 14 58 1.2E-16 T 28-03-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 CU254_RS29565 c45288a2c0052f03fdd204effd8311e6 481 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 17 215 1.6E-50 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CU254_RS29565 c45288a2c0052f03fdd204effd8311e6 481 SUPERFAMILY SSF89562 263 437 2.88E-37 T 28-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CU254_RS29565 c45288a2c0052f03fdd204effd8311e6 481 Pfam PF03737 Aldolase/RraA 268 429 6.4E-32 T 28-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CU254_RS29565 c45288a2c0052f03fdd204effd8311e6 481 SUPERFAMILY SSF56529 8 202 2.35E-55 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CU254_RS29565 c45288a2c0052f03fdd204effd8311e6 481 Gene3D G3DSA:3.90.850.10 1 218 2.5E-62 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CU254_RS29565 c45288a2c0052f03fdd204effd8311e6 481 Gene3D G3DSA:3.50.30.40 260 449 2.4E-51 T 28-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CU254_RS03645 2e2e1a16ef4f343285b87b8fd6ce6086 336 SUPERFAMILY SSF51445 30 326 1.55E-37 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS03645 2e2e1a16ef4f343285b87b8fd6ce6086 336 Gene3D G3DSA:3.20.20.80 30 323 1.8E-36 T 28-03-2018 CU254_RS03645 2e2e1a16ef4f343285b87b8fd6ce6086 336 ProSitePatterns PS01095 Chitinases family 18 active site. 145 153 - T 28-03-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 CU254_RS03645 2e2e1a16ef4f343285b87b8fd6ce6086 336 Pfam PF00704 Glycosyl hydrolases family 18 33 284 3.0E-20 T 28-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 CU254_RS38470 899e0182f2caaf82009edc38ee506ed4 110 SUPERFAMILY SSF142906 1 103 5.36E-8 T 28-03-2018 CU254_RS38470 899e0182f2caaf82009edc38ee506ed4 110 Pfam PF04237 YjbR 16 101 4.4E-12 T 28-03-2018 IPR007351 Uncharacterised protein YjbR CU254_RS41285 eb947544ac68583c4c7294a3ff1b746e 175 SUPERFAMILY SSF47413 32 97 6.57E-6 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS41285 eb947544ac68583c4c7294a3ff1b746e 175 Gene3D G3DSA:1.10.260.40 33 108 7.7E-7 T 28-03-2018 CU254_RS25315 d2a1e87588c9f439aef0591cc3d7237e 388 Pfam PF01266 FAD dependent oxidoreductase 3 350 9.3E-41 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CU254_RS25315 d2a1e87588c9f439aef0591cc3d7237e 388 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 210 231 1.0E-5 T 28-03-2018 CU254_RS25315 d2a1e87588c9f439aef0591cc3d7237e 388 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 27 1.0E-5 T 28-03-2018 CU254_RS25315 d2a1e87588c9f439aef0591cc3d7237e 388 Gene3D G3DSA:3.50.50.60 1 387 4.4E-39 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS25315 d2a1e87588c9f439aef0591cc3d7237e 388 SUPERFAMILY SSF51905 2 216 8.42E-50 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS25315 d2a1e87588c9f439aef0591cc3d7237e 388 SUPERFAMILY SSF51905 314 371 8.42E-50 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS12665 a15934d5414cdf5373a745bc762b56c1 246 Pfam PF13586 Transposase DDE domain 82 145 3.5E-8 T 28-03-2018 IPR025668 Transposase DDE domain CU254_RS15400 215a4f1657832d36168abc16a2d84770 596 Pfam PF13520 Amino acid permease 49 415 3.0E-27 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CU254_RS40545 b2d6b0bdf08e922053ea3cc4f49c9322 106 Gene3D G3DSA:3.30.70.100 6 98 3.0E-21 T 28-03-2018 CU254_RS40545 b2d6b0bdf08e922053ea3cc4f49c9322 106 SUPERFAMILY SSF54909 3 103 5.37E-29 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS38920 8bc7555e3f25605353440648e622d6d1 257 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 162 169 - T 28-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 CU254_RS38920 8bc7555e3f25605353440648e622d6d1 257 SMART SM00518 2 256 2.1E-43 T 28-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 CU254_RS38920 8bc7555e3f25605353440648e622d6d1 257 Pfam PF01261 Xylose isomerase-like TIM barrel 14 217 6.2E-23 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CU254_RS38920 8bc7555e3f25605353440648e622d6d1 257 Gene3D G3DSA:3.20.20.150 3 257 1.6E-37 T 28-03-2018 CU254_RS38920 8bc7555e3f25605353440648e622d6d1 257 SUPERFAMILY SSF51658 1 245 1.24E-51 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CU254_RS38920 8bc7555e3f25605353440648e622d6d1 257 ProSitePatterns PS00729 AP endonucleases family 2 signature 1. 56 64 - T 28-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 CU254_RS07130 eeb2aa61102b0ca3be89fc09e7a47be1 160 Gene3D G3DSA:3.40.630.30 1 160 1.2E-23 T 28-03-2018 CU254_RS07130 eeb2aa61102b0ca3be89fc09e7a47be1 160 Pfam PF00583 Acetyltransferase (GNAT) family 30 134 1.4E-9 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS07130 eeb2aa61102b0ca3be89fc09e7a47be1 160 SUPERFAMILY SSF55729 5 145 5.91E-24 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS16100 0cc3f9e2110159cd1699d2ff974eb5f7 69 SUPERFAMILY SSF160582 3 65 1.11E-26 T 28-03-2018 CU254_RS16100 0cc3f9e2110159cd1699d2ff974eb5f7 69 Gene3D G3DSA:3.90.820.10 1 64 2.1E-30 T 28-03-2018 CU254_RS16100 0cc3f9e2110159cd1699d2ff974eb5f7 69 Pfam PF03621 MbtH-like protein 3 49 6.9E-19 T 28-03-2018 IPR005153 MbtH-like protein CU254_RS16100 0cc3f9e2110159cd1699d2ff974eb5f7 69 SMART SM00923 1 49 1.9E-16 T 28-03-2018 IPR005153 MbtH-like protein CU254_RS11315 428a38db97448ee658bdfb0e5c3a799a 134 Pfam PF06103 Bacterial protein of unknown function (DUF948) 6 86 1.8E-21 T 28-03-2018 IPR009293 Uncharacterised protein family UPF0478 CU254_RS11960 951880bb7e12556fa263bf1ba0a71fac 152 Gene3D G3DSA:3.40.30.10 1 151 1.2E-35 T 28-03-2018 CU254_RS11960 951880bb7e12556fa263bf1ba0a71fac 152 Pfam PF00578 AhpC/TSA family 4 125 5.1E-32 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CU254_RS11960 951880bb7e12556fa263bf1ba0a71fac 152 PIRSF PIRSF000239 1 149 3.8E-18 T 28-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CU254_RS11960 951880bb7e12556fa263bf1ba0a71fac 152 SUPERFAMILY SSF52833 2 148 3.17E-44 T 28-03-2018 IPR012336 Thioredoxin-like fold CU254_RS17570 cb02a26ebde00cc4838abf0ff3c70f7c 281 Gene3D G3DSA:3.30.450.40 101 269 6.7E-50 T 28-03-2018 IPR029016 GAF domain-like CU254_RS17570 cb02a26ebde00cc4838abf0ff3c70f7c 281 Pfam PF01614 Bacterial transcriptional regulator 143 265 9.9E-31 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal CU254_RS17570 cb02a26ebde00cc4838abf0ff3c70f7c 281 Pfam PF09339 IclR helix-turn-helix domain 28 76 3.6E-12 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS17570 cb02a26ebde00cc4838abf0ff3c70f7c 281 SUPERFAMILY SSF55781 104 265 5.76E-48 T 28-03-2018 IPR029016 GAF domain-like CU254_RS17570 cb02a26ebde00cc4838abf0ff3c70f7c 281 SUPERFAMILY SSF46785 28 93 7.4E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS17570 cb02a26ebde00cc4838abf0ff3c70f7c 281 Gene3D G3DSA:1.10.10.10 22 97 1.4E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS05980 5014068374fe7ae86911448e6034b5ee 489 Gene3D G3DSA:1.20.5.1230 67 463 4.9E-5 T 28-03-2018 CU254_RS21500 bc6a7dd9f4d09e5a43788ae3a03dabd3 251 Gene3D G3DSA:3.30.70.980 182 251 2.8E-13 T 28-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CU254_RS21500 bc6a7dd9f4d09e5a43788ae3a03dabd3 251 Gene3D G3DSA:1.10.10.200 1 80 5.1E-28 T 28-03-2018 IPR017856 Integrase, N-terminal zinc-binding domain-like CU254_RS21500 bc6a7dd9f4d09e5a43788ae3a03dabd3 251 SUPERFAMILY SSF75625 3 248 2.35E-88 T 28-03-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CU254_RS21500 bc6a7dd9f4d09e5a43788ae3a03dabd3 251 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 240 1.6E-97 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CU254_RS21500 bc6a7dd9f4d09e5a43788ae3a03dabd3 251 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 242 34.642 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CU254_RS21500 bc6a7dd9f4d09e5a43788ae3a03dabd3 251 Gene3D G3DSA:3.30.70.980 86 180 4.0E-30 T 28-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CU254_RS21500 bc6a7dd9f4d09e5a43788ae3a03dabd3 251 Pfam PF01709 Transcriptional regulator 5 240 5.0E-89 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CU254_RS16745 6a0468979a1bb6e25457bcb94e03d043 372 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 7 321 3.1E-13 T 28-03-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CU254_RS16745 6a0468979a1bb6e25457bcb94e03d043 372 SUPERFAMILY SSF51726 2 346 6.54E-48 T 28-03-2018 CU254_RS16745 6a0468979a1bb6e25457bcb94e03d043 372 Gene3D G3DSA:3.20.20.210 1 354 1.1E-63 T 28-03-2018 CU254_RS36630 3721d8de7a3a572fd01d043911e0fdc0 192 Gene3D G3DSA:3.40.630.30 1 192 1.3E-27 T 28-03-2018 CU254_RS36630 3721d8de7a3a572fd01d043911e0fdc0 192 SUPERFAMILY SSF55729 6 176 3.03E-37 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS36630 3721d8de7a3a572fd01d043911e0fdc0 192 Pfam PF13302 Acetyltransferase (GNAT) domain 14 149 7.2E-17 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS05315 7705e6218a83c2c52956e93e3da65fed 329 SUPERFAMILY SSF47616 154 317 5.43E-35 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like CU254_RS05315 7705e6218a83c2c52956e93e3da65fed 329 Gene3D G3DSA:3.40.30.10 10 164 4.1E-20 T 28-03-2018 CU254_RS05315 7705e6218a83c2c52956e93e3da65fed 329 SUPERFAMILY SSF52833 17 89 3.02E-5 T 28-03-2018 IPR012336 Thioredoxin-like fold CU254_RS05315 7705e6218a83c2c52956e93e3da65fed 329 PIRSF PIRSF015753 1 301 1.9E-106 T 28-03-2018 IPR016639 Glutathione S-transferase (GST) KEGG: 00480+2.5.1.18|KEGG: 00980+2.5.1.18|KEGG: 00982+2.5.1.18|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7533 CU254_RS05315 7705e6218a83c2c52956e93e3da65fed 329 Pfam PF13410 Glutathione S-transferase, C-terminal domain 180 250 6.9E-13 T 28-03-2018 CU254_RS05315 7705e6218a83c2c52956e93e3da65fed 329 Pfam PF13409 Glutathione S-transferase, N-terminal domain 40 129 1.8E-9 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CU254_RS05315 7705e6218a83c2c52956e93e3da65fed 329 Gene3D G3DSA:1.20.1050.10 165 305 2.5E-43 T 28-03-2018 CU254_RS27595 3010962646abc1799cd701f118c4f185 665 Pfam PF05425 Copper resistance protein D 235 331 5.6E-19 T 28-03-2018 IPR008457 Copper resistance protein D GO:0016021 CU254_RS27595 3010962646abc1799cd701f118c4f185 665 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 384 628 1.1E-89 T 28-03-2018 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related CU254_RS00930 3401d57c4fa8999c0b0f5d84e1f8f0cb 144 SUPERFAMILY SSF55961 1 143 1.16E-14 T 28-03-2018 CU254_RS00930 3401d57c4fa8999c0b0f5d84e1f8f0cb 144 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 4 142 3.0E-18 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase CU254_RS00930 3401d57c4fa8999c0b0f5d84e1f8f0cb 144 PIRSF PIRSF017371 1 144 3.4E-56 T 28-03-2018 IPR014488 Uncharacterised conserved protein UCP017371 CU254_RS00930 3401d57c4fa8999c0b0f5d84e1f8f0cb 144 Gene3D G3DSA:3.30.530.20 3 142 1.9E-16 T 28-03-2018 IPR023393 START-like domain CU254_RS00915 c85750a5daad8505d94133c6a3def06a 237 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 48 222 9.5E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS00915 c85750a5daad8505d94133c6a3def06a 237 Gene3D G3DSA:1.10.3720.10 2 227 6.0E-29 T 28-03-2018 CU254_RS00915 c85750a5daad8505d94133c6a3def06a 237 SUPERFAMILY SSF161098 28 211 1.96E-29 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS11085 82672f609737d89e428a4cd0bd1f225a 436 SUPERFAMILY SSF89796 178 413 2.22E-54 T 28-03-2018 IPR023606 CoA-transferase family III domain CU254_RS11085 82672f609737d89e428a4cd0bd1f225a 436 Gene3D G3DSA:3.30.1540.10 75 159 2.0E-10 T 28-03-2018 CU254_RS11085 82672f609737d89e428a4cd0bd1f225a 436 Pfam PF02515 CoA-transferase family III 182 365 4.5E-42 T 28-03-2018 IPR003673 CoA-transferase family III GO:0003824 CU254_RS11085 82672f609737d89e428a4cd0bd1f225a 436 Gene3D G3DSA:3.40.50.10540 174 384 2.2E-62 T 28-03-2018 IPR023606 CoA-transferase family III domain CU254_RS11085 82672f609737d89e428a4cd0bd1f225a 436 SUPERFAMILY SSF89796 6 170 1.14E-24 T 28-03-2018 IPR023606 CoA-transferase family III domain CU254_RS17265 0ff66974dd89673968ef977f3d510ff9 315 Pfam PF08012 Protein of unknown function (DUF1702) 23 309 3.9E-67 T 28-03-2018 IPR012964 Protein of unknown function DUF1702 CU254_RS35110 589dd9a0508d6f7f8673ffa3c37b32af 389 Pfam PF11228 Protein of unknown function (DUF3027) 37 227 2.2E-79 T 28-03-2018 IPR021391 Protein of unknown function DUF3027 CU254_RS24355 7030441d74410303afcd9c1dd6d2b0ce 174 Pfam PF03551 Transcriptional regulator PadR-like family 7 78 2.5E-12 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CU254_RS24355 7030441d74410303afcd9c1dd6d2b0ce 174 SUPERFAMILY SSF46785 3 171 2.41E-34 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS24355 7030441d74410303afcd9c1dd6d2b0ce 174 Gene3D G3DSA:1.10.10.10 1 89 4.0E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS24355 7030441d74410303afcd9c1dd6d2b0ce 174 Pfam PF10400 Virulence activator alpha C-term 90 169 9.5E-13 T 28-03-2018 IPR018309 Transcription regulator PadR, C-terminal CU254_RS27930 d1c0f32d7e61366136c2e7f05b7481b9 372 SUPERFAMILY SSF53474 2 371 2.27E-79 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS27930 d1c0f32d7e61366136c2e7f05b7481b9 372 Gene3D G3DSA:3.40.50.1820 2 372 1.7E-71 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS27930 d1c0f32d7e61366136c2e7f05b7481b9 372 Pfam PF06441 Epoxide hydrolase N terminus 5 109 4.2E-34 T 28-03-2018 IPR010497 Epoxide hydrolase, N-terminal KEGG: 00980+3.3.2.9|Reactome: R-HSA-211945 CU254_RS27930 d1c0f32d7e61366136c2e7f05b7481b9 372 PIRSF PIRSF001112 1 372 1.0E-104 T 28-03-2018 IPR016292 Epoxide hydrolase GO:0033961 KEGG: 00980+3.3.2.9|Reactome: R-HSA-211945 CU254_RS27930 d1c0f32d7e61366136c2e7f05b7481b9 372 PRINTS PR00412 Epoxide hydrolase signature 130 145 7.0E-11 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS27930 d1c0f32d7e61366136c2e7f05b7481b9 372 PRINTS PR00412 Epoxide hydrolase signature 101 119 7.0E-11 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS27930 d1c0f32d7e61366136c2e7f05b7481b9 372 PRINTS PR00412 Epoxide hydrolase signature 345 367 7.0E-11 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS27930 d1c0f32d7e61366136c2e7f05b7481b9 372 PRINTS PR00412 Epoxide hydrolase signature 175 188 7.0E-11 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS26475 7cb1d866c213f69d7ae15a1216054dfb 165 SUPERFAMILY SSF82607 8 91 4.05E-8 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CU254_RS26475 7cb1d866c213f69d7ae15a1216054dfb 165 Pfam PF02575 YbaB/EbfC DNA-binding family 9 91 1.2E-12 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CU254_RS26475 7cb1d866c213f69d7ae15a1216054dfb 165 Gene3D G3DSA:3.30.1310.10 1 96 7.2E-18 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CU254_RS15085 fc35addde70c9015d371a91838bb8546 465 Gene3D G3DSA:3.50.50.60 1 378 5.6E-60 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS15085 fc35addde70c9015d371a91838bb8546 465 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 7.2E-46 T 28-03-2018 CU254_RS15085 fc35addde70c9015d371a91838bb8546 465 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 283 299 7.2E-46 T 28-03-2018 CU254_RS15085 fc35addde70c9015d371a91838bb8546 465 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 268 283 7.2E-46 T 28-03-2018 CU254_RS15085 fc35addde70c9015d371a91838bb8546 465 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 319 335 7.2E-46 T 28-03-2018 CU254_RS15085 fc35addde70c9015d371a91838bb8546 465 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 301 319 7.2E-46 T 28-03-2018 CU254_RS15085 fc35addde70c9015d371a91838bb8546 465 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 142 157 7.2E-46 T 28-03-2018 CU254_RS15085 fc35addde70c9015d371a91838bb8546 465 Pfam PF01494 FAD binding domain 3 333 4.4E-79 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CU254_RS15085 fc35addde70c9015d371a91838bb8546 465 SUPERFAMILY SSF51905 264 377 7.73E-58 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS15085 fc35addde70c9015d371a91838bb8546 465 SUPERFAMILY SSF51905 2 163 7.73E-58 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS03805 e137bffb89c27327e8c1359c78067281 301 SUPERFAMILY SSF56112 48 270 1.45E-13 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS03805 e137bffb89c27327e8c1359c78067281 301 Gene3D G3DSA:3.90.1200.10 74 300 4.3E-4 T 28-03-2018 CU254_RS03805 e137bffb89c27327e8c1359c78067281 301 Pfam PF04655 Aminoglycoside/hydroxyurea antibiotic resistance kinase 39 272 4.2E-30 T 28-03-2018 IPR006748 Aminoglycoside/hydroxyurea antibiotic resistance kinase GO:0006468|GO:0016773|GO:0019748 CU254_RS37995 015529598ce0b1bf9789f127d2589756 640 Pfam PF13538 UvrD-like helicase C-terminal domain 580 635 4.6E-7 T 28-03-2018 IPR027785 UvrD-like helicase C-terminal domain CU254_RS37995 015529598ce0b1bf9789f127d2589756 640 Gene3D G3DSA:3.40.50.300 467 639 1.3E-17 T 28-03-2018 CU254_RS37995 015529598ce0b1bf9789f127d2589756 640 Pfam PF13245 AAA domain 219 449 4.0E-15 T 28-03-2018 CU254_RS37995 015529598ce0b1bf9789f127d2589756 640 Gene3D G3DSA:3.40.50.300 206 462 6.6E-29 T 28-03-2018 CU254_RS37995 015529598ce0b1bf9789f127d2589756 640 SUPERFAMILY SSF52540 200 634 1.12E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS42265 a2c7a65b6f171e711de7c584321c86c5 200 SUPERFAMILY SSF52540 61 170 2.11E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS42265 a2c7a65b6f171e711de7c584321c86c5 200 Gene3D G3DSA:3.40.50.300 73 197 1.1E-6 T 28-03-2018 CU254_RS36660 5501c6957f6732b36788b88b1ef01e7b 458 SUPERFAMILY SSF56059 170 374 3.54E-15 T 28-03-2018 CU254_RS36660 5501c6957f6732b36788b88b1ef01e7b 458 Gene3D G3DSA:3.30.470.20 163 409 5.6E-21 T 28-03-2018 CU254_RS01205 9d9b2d556a9b1d126957a019c364c5c9 434 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 7 428 95.603 T 28-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 CU254_RS01205 9d9b2d556a9b1d126957a019c364c5c9 434 Pfam PF00202 Aminotransferase class-III 37 421 1.7E-85 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CU254_RS01205 9d9b2d556a9b1d126957a019c364c5c9 434 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 8 427 6.1E-178 T 28-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 CU254_RS01205 9d9b2d556a9b1d126957a019c364c5c9 434 SUPERFAMILY SSF53383 5 424 1.31E-116 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS01205 9d9b2d556a9b1d126957a019c364c5c9 434 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 238 274 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CU254_RS01205 9d9b2d556a9b1d126957a019c364c5c9 434 Gene3D G3DSA:3.90.1150.10 1 155 3.0E-41 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS01205 9d9b2d556a9b1d126957a019c364c5c9 434 Gene3D G3DSA:3.90.1150.10 316 431 6.0E-14 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS01205 9d9b2d556a9b1d126957a019c364c5c9 434 Gene3D G3DSA:3.40.640.10 171 315 1.7E-41 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS39670 a4a27029000314ea8cdce0f2dc3733a3 216 SUPERFAMILY SSF51735 1 206 9.51E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS39670 a4a27029000314ea8cdce0f2dc3733a3 216 Gene3D G3DSA:3.40.50.720 1 216 2.0E-28 T 28-03-2018 CU254_RS39670 a4a27029000314ea8cdce0f2dc3733a3 216 Pfam PF13460 NAD(P)H-binding 7 193 1.8E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS08510 31ed56aa1f98a85e7fac884e9b848e41 133 SUPERFAMILY SSF54593 4 128 4.97E-30 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS08510 31ed56aa1f98a85e7fac884e9b848e41 133 Gene3D G3DSA:3.10.180.10 1 132 2.1E-26 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS08510 31ed56aa1f98a85e7fac884e9b848e41 133 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 126 1.3E-17 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CU254_RS26695 c36e4da2b798eec11004e68745fa4917 124 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 13 108 3.2E-9 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CU254_RS26695 c36e4da2b798eec11004e68745fa4917 124 Gene3D G3DSA:3.10.180.10 6 122 7.9E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS26695 c36e4da2b798eec11004e68745fa4917 124 SUPERFAMILY SSF54593 10 116 1.32E-21 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS30895 408811edf8d179d95f6cf65594735d4f 199 SUPERFAMILY SSF46689 2 76 1.32E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS30895 408811edf8d179d95f6cf65594735d4f 199 Gene3D G3DSA:1.10.357.10 65 193 6.9E-21 T 28-03-2018 CU254_RS30895 408811edf8d179d95f6cf65594735d4f 199 ProSitePatterns PS01081 TetR-type HTH domain signature. 27 58 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CU254_RS30895 408811edf8d179d95f6cf65594735d4f 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 58 3.1E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS30895 408811edf8d179d95f6cf65594735d4f 199 Gene3D G3DSA:1.10.10.60 1 36 4.0E-16 T 28-03-2018 CU254_RS30895 408811edf8d179d95f6cf65594735d4f 199 Gene3D G3DSA:1.10.260.40 37 64 4.0E-13 T 28-03-2018 CU254_RS30895 408811edf8d179d95f6cf65594735d4f 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 3.9E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS30895 408811edf8d179d95f6cf65594735d4f 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 3.9E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS19445 db8fd9dd279adc1afc5cad5c0e575982 269 TIGRFAM TIGR03843 TIGR03843: conserved hypothetical protein 18 269 1.3E-112 T 28-03-2018 IPR022292 Conserved hypothetical protein CHP03843 CU254_RS14195 bd7e77ca1e228d7d392ca7e682ce369c 167 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 57 141 7.6E-6 T 28-03-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 CU254_RS14195 bd7e77ca1e228d7d392ca7e682ce369c 167 SUPERFAMILY SSF55166 32 148 4.19E-15 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CU254_RS14195 bd7e77ca1e228d7d392ca7e682ce369c 167 Gene3D G3DSA:3.30.1380.10 126 156 0.28 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CU254_RS14195 bd7e77ca1e228d7d392ca7e682ce369c 167 Gene3D G3DSA:3.30.1380.10 23 125 8.9E-9 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CU254_RS21065 0b673fc3c6bcd11ce5607876ce5ef671 538 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 387 534 9.5E-25 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CU254_RS21065 0b673fc3c6bcd11ce5607876ce5ef671 538 Gene3D G3DSA:3.40.50.1220 184 344 7.0E-26 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CU254_RS21065 0b673fc3c6bcd11ce5607876ce5ef671 538 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 6 172 6.5E-37 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CU254_RS21065 0b673fc3c6bcd11ce5607876ce5ef671 538 Gene3D G3DSA:3.40.50.970 345 538 8.0E-30 T 28-03-2018 CU254_RS21065 0b673fc3c6bcd11ce5607876ce5ef671 538 SUPERFAMILY SSF52518 6 178 1.47E-39 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS21065 0b673fc3c6bcd11ce5607876ce5ef671 538 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 193 323 3.8E-17 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CU254_RS21065 0b673fc3c6bcd11ce5607876ce5ef671 538 Gene3D G3DSA:3.40.50.970 1 183 1.0E-35 T 28-03-2018 CU254_RS21065 0b673fc3c6bcd11ce5607876ce5ef671 538 SUPERFAMILY SSF52518 356 536 1.73E-35 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS21065 0b673fc3c6bcd11ce5607876ce5ef671 538 SUPERFAMILY SSF52467 188 337 5.93E-39 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CU254_RS01610 6d196e2eee61e0ce66ed204034727a79 282 Hamap MF_00188 Protease HtpX [htpX]. 7 278 27.256 T 28-03-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 CU254_RS01610 6d196e2eee61e0ce66ed204034727a79 282 Gene3D G3DSA:3.30.2010.10 58 151 4.0E-21 T 28-03-2018 CU254_RS01610 6d196e2eee61e0ce66ed204034727a79 282 Pfam PF01435 Peptidase family M48 68 278 4.2E-37 T 28-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CU254_RS20690 6ff9913754a87d38f7d2f43910a52b64 401 Gene3D G3DSA:1.20.1250.20 209 390 9.4E-13 T 28-03-2018 CU254_RS20690 6ff9913754a87d38f7d2f43910a52b64 401 Gene3D G3DSA:1.20.1250.20 10 208 5.3E-23 T 28-03-2018 CU254_RS20690 6ff9913754a87d38f7d2f43910a52b64 401 SUPERFAMILY SSF103473 12 391 1.96E-48 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS20690 6ff9913754a87d38f7d2f43910a52b64 401 Pfam PF07690 Major Facilitator Superfamily 27 332 1.4E-34 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS28025 2adc3f177155f848b2a5677147b7dd4b 419 SUPERFAMILY SSF103473 28 413 1.31E-34 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS28025 2adc3f177155f848b2a5677147b7dd4b 419 Gene3D G3DSA:1.20.1250.20 224 415 1.9E-12 T 28-03-2018 CU254_RS28025 2adc3f177155f848b2a5677147b7dd4b 419 Pfam PF07690 Major Facilitator Superfamily 35 353 7.4E-18 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS28025 2adc3f177155f848b2a5677147b7dd4b 419 Gene3D G3DSA:1.20.1250.20 23 223 2.2E-13 T 28-03-2018 CU254_RS10500 d7612a96930875c893dc607927c7f728 344 PIRSF PIRSF015921 13 344 9.0E-72 T 28-03-2018 IPR012171 Fatty acid desaturase GO:0006629|GO:0016021|GO:0016491 CU254_RS10500 d7612a96930875c893dc607927c7f728 344 Pfam PF00487 Fatty acid desaturase 62 319 4.4E-36 T 28-03-2018 IPR005804 Fatty acid desaturase domain GO:0006629 CU254_RS26435 b9bca0de1f47da5816c601f675956986 112 Gene3D G3DSA:3.40.140.10 2 111 5.4E-9 T 28-03-2018 CU254_RS26435 b9bca0de1f47da5816c601f675956986 112 SUPERFAMILY SSF53927 7 77 4.51E-8 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CU254_RS08070 2ff751a0cc6fb4547c679a1d2ceda379 280 Gene3D G3DSA:3.10.180.10 16 134 2.1E-10 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS08070 2ff751a0cc6fb4547c679a1d2ceda379 280 SUPERFAMILY SSF54593 17 132 6.2E-13 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS08070 2ff751a0cc6fb4547c679a1d2ceda379 280 SUPERFAMILY SSF54593 149 261 2.15E-14 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS08070 2ff751a0cc6fb4547c679a1d2ceda379 280 Gene3D G3DSA:3.10.180.10 150 273 4.0E-15 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS38850 db215749231d0ff537cf8a66f3b07d58 466 Gene3D G3DSA:2.60.40.10 327 442 1.2E-19 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS38850 db215749231d0ff537cf8a66f3b07d58 466 SUPERFAMILY SSF117074 319 392 9.94E-17 T 28-03-2018 CU254_RS38850 db215749231d0ff537cf8a66f3b07d58 466 Pfam PF17210 SdrD B-like domain 327 440 2.2E-26 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CU254_RS38850 db215749231d0ff537cf8a66f3b07d58 466 Gene3D G3DSA:2.60.120.260 43 207 1.1E-5 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS38850 db215749231d0ff537cf8a66f3b07d58 466 Gene3D G3DSA:2.60.40.10 208 326 1.3E-10 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS38850 db215749231d0ff537cf8a66f3b07d58 466 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 233 260 6.3E-4 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CU254_RS22450 3d85cca58ef364753f1d03d17f090846 311 PRINTS PR00474 Glutamate 5-kinase family signature 251 271 1.8E-8 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CU254_RS22450 3d85cca58ef364753f1d03d17f090846 311 PRINTS PR00474 Glutamate 5-kinase family signature 68 82 1.8E-8 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CU254_RS22450 3d85cca58ef364753f1d03d17f090846 311 PRINTS PR00474 Glutamate 5-kinase family signature 200 227 1.8E-8 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CU254_RS22450 3d85cca58ef364753f1d03d17f090846 311 Hamap MF_00082_B Acetylglutamate kinase [argB]. 35 301 34.152 T 28-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CU254_RS22450 3d85cca58ef364753f1d03d17f090846 311 Gene3D G3DSA:3.40.1160.10 2 305 1.3E-70 T 28-03-2018 CU254_RS22450 3d85cca58ef364753f1d03d17f090846 311 SUPERFAMILY SSF53633 16 302 4.84E-85 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CU254_RS22450 3d85cca58ef364753f1d03d17f090846 311 PIRSF PIRSF000728 20 300 3.3E-100 T 28-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CU254_RS22450 3d85cca58ef364753f1d03d17f090846 311 Pfam PF00696 Amino acid kinase family 38 278 1.2E-42 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CU254_RS22450 3d85cca58ef364753f1d03d17f090846 311 TIGRFAM TIGR00761 argB: acetylglutamate kinase 38 276 1.5E-78 T 28-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CU254_RS17590 049c49f385e66276015d0e913b0f1124 82 Pfam PF11755 Protein of unknown function (DUF3311) 10 64 5.7E-13 T 28-03-2018 IPR021741 Protein of unknown function DUF3311 CU254_RS32400 58ffd77fc0281d595525d3fd8cb33105 302 SUPERFAMILY SSF89392 48 282 3.73E-9 T 28-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX CU254_RS32400 58ffd77fc0281d595525d3fd8cb33105 302 Gene3D G3DSA:3.40.190.10 1 249 3.4E-8 T 28-03-2018 CU254_RS12230 69b07e63606d00d6a2a05b419d3dcd70 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 5.7E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS12230 69b07e63606d00d6a2a05b419d3dcd70 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 5.7E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS12230 69b07e63606d00d6a2a05b419d3dcd70 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 5.7E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS12230 69b07e63606d00d6a2a05b419d3dcd70 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 5.7E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS12230 69b07e63606d00d6a2a05b419d3dcd70 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 5.7E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS12230 69b07e63606d00d6a2a05b419d3dcd70 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 5.7E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS12230 69b07e63606d00d6a2a05b419d3dcd70 262 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 258 1.0E-48 T 28-03-2018 CU254_RS12230 69b07e63606d00d6a2a05b419d3dcd70 262 Gene3D G3DSA:3.40.50.720 1 257 6.5E-62 T 28-03-2018 CU254_RS12230 69b07e63606d00d6a2a05b419d3dcd70 262 SUPERFAMILY SSF51735 6 258 1.11E-64 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS24425 70f1af93d075e5e2d2a4119f18d6b24d 214 Pfam PF01252 Signal peptidase (SPase) II 54 196 4.7E-30 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CU254_RS24425 70f1af93d075e5e2d2a4119f18d6b24d 214 ProSitePatterns PS00855 Signal peptidases II signature. 137 149 - T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CU254_RS24425 70f1af93d075e5e2d2a4119f18d6b24d 214 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 45 202 15.06 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CU254_RS24425 70f1af93d075e5e2d2a4119f18d6b24d 214 TIGRFAM TIGR00077 lspA: signal peptidase II 49 198 4.0E-29 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CU254_RS24425 70f1af93d075e5e2d2a4119f18d6b24d 214 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 134 149 1.4E-16 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CU254_RS24425 70f1af93d075e5e2d2a4119f18d6b24d 214 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 177 193 1.4E-16 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CU254_RS24425 70f1af93d075e5e2d2a4119f18d6b24d 214 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 92 100 1.4E-16 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CU254_RS26080 4f6955e0136760e5f839da32b7161145 531 Pfam PF01019 Gamma-glutamyltranspeptidase 29 526 1.7E-95 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CU254_RS26080 4f6955e0136760e5f839da32b7161145 531 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 125 144 2.7E-32 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CU254_RS26080 4f6955e0136760e5f839da32b7161145 531 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 252 271 2.7E-32 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CU254_RS26080 4f6955e0136760e5f839da32b7161145 531 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 400 415 2.7E-32 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CU254_RS26080 4f6955e0136760e5f839da32b7161145 531 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 368 386 2.7E-32 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CU254_RS26080 4f6955e0136760e5f839da32b7161145 531 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 36 61 2.7E-32 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CU254_RS26080 4f6955e0136760e5f839da32b7161145 531 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 424 441 2.7E-32 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CU254_RS26080 4f6955e0136760e5f839da32b7161145 531 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 107 125 2.7E-32 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CU254_RS26080 4f6955e0136760e5f839da32b7161145 531 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 344 362 2.7E-32 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CU254_RS26080 4f6955e0136760e5f839da32b7161145 531 SUPERFAMILY SSF56235 7 530 3.09E-106 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CU254_RS36250 97e343e10c7108d4452b00eb2b7b4c00 282 SUPERFAMILY SSF53335 46 258 4.14E-33 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS36250 97e343e10c7108d4452b00eb2b7b4c00 282 Pfam PF08241 Methyltransferase domain 80 169 4.8E-19 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CU254_RS36250 97e343e10c7108d4452b00eb2b7b4c00 282 Gene3D G3DSA:3.40.50.150 25 263 9.0E-33 T 28-03-2018 CU254_RS22615 5d7b3b70f4944f4843eb3356046c27e1 198 SMART SM00060 109 187 5.1 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CU254_RS22615 5d7b3b70f4944f4843eb3356046c27e1 198 SMART SM00060 14 91 0.18 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CU254_RS22615 5d7b3b70f4944f4843eb3356046c27e1 198 SUPERFAMILY SSF49265 16 195 7.59E-14 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CU254_RS22615 5d7b3b70f4944f4843eb3356046c27e1 198 Gene3D G3DSA:2.60.40.10 107 198 5.7E-10 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS22615 5d7b3b70f4944f4843eb3356046c27e1 198 Gene3D G3DSA:2.60.40.10 6 106 1.3E-10 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS07135 4936e8f8e48c9c5e32ce1e2c3fd9ce34 176 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 12 45 1.7E-5 T 28-03-2018 IPR001451 Hexapeptide repeat CU254_RS07135 4936e8f8e48c9c5e32ce1e2c3fd9ce34 176 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 88 121 2.8E-5 T 28-03-2018 IPR001451 Hexapeptide repeat CU254_RS07135 4936e8f8e48c9c5e32ce1e2c3fd9ce34 176 Gene3D G3DSA:2.160.10.10 1 169 4.8E-36 T 28-03-2018 CU254_RS07135 4936e8f8e48c9c5e32ce1e2c3fd9ce34 176 SUPERFAMILY SSF51161 3 149 2.36E-37 T 28-03-2018 IPR011004 Trimeric LpxA-like CU254_RS32210 5912c73294fc4284bc83d445345cd1da 256 SUPERFAMILY SSF52540 4 222 1.13E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS32210 5912c73294fc4284bc83d445345cd1da 256 Gene3D G3DSA:3.40.50.300 2 241 1.7E-59 T 28-03-2018 CU254_RS32210 5912c73294fc4284bc83d445345cd1da 256 SMART SM00382 30 219 1.5E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS32210 5912c73294fc4284bc83d445345cd1da 256 Pfam PF00005 ABC transporter 21 162 1.0E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS32210 5912c73294fc4284bc83d445345cd1da 256 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS18440 b3480669b152ff4aac78bc639e4af965 167 Gene3D G3DSA:3.40.630.30 2 167 1.2E-19 T 28-03-2018 CU254_RS18440 b3480669b152ff4aac78bc639e4af965 167 Pfam PF13302 Acetyltransferase (GNAT) domain 12 151 1.6E-23 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS18440 b3480669b152ff4aac78bc639e4af965 167 SUPERFAMILY SSF55729 7 157 2.36E-26 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS27335 a63857d7f44d399d835d15645ca7fe50 133 Gene3D G3DSA:3.30.1330.40 4 133 5.9E-26 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CU254_RS27335 a63857d7f44d399d835d15645ca7fe50 133 Pfam PF01042 Endoribonuclease L-PSP 14 123 8.4E-20 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family CU254_RS27335 a63857d7f44d399d835d15645ca7fe50 133 SUPERFAMILY SSF55298 10 125 9.27E-28 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CU254_RS29855 0eb6e13c00ec75bf5cf6994088f2cc04 404 SUPERFAMILY SSF53756 192 325 1.19E-6 T 28-03-2018 CU254_RS20715 fc17d3c8a38867dfeb4962822953a55b 440 Gene3D G3DSA:1.20.1250.20 211 433 2.2E-24 T 28-03-2018 CU254_RS20715 fc17d3c8a38867dfeb4962822953a55b 440 Gene3D G3DSA:1.20.1250.20 16 210 1.1E-27 T 28-03-2018 CU254_RS20715 fc17d3c8a38867dfeb4962822953a55b 440 Pfam PF07690 Major Facilitator Superfamily 32 345 1.7E-41 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS20715 fc17d3c8a38867dfeb4962822953a55b 440 SUPERFAMILY SSF103473 14 427 1.96E-64 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS29720 988f1c58fcca809bac0295afdd01c9cd 288 TIGRFAM TIGR02957 SigX4: RNA polymerase sigma-70 factor, TIGR02957 family 10 285 2.4E-105 T 28-03-2018 IPR014303 RNA polymerase sigma-70, ECF type CU254_RS29720 988f1c58fcca809bac0295afdd01c9cd 288 SUPERFAMILY SSF88659 106 161 1.33E-11 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS29720 988f1c58fcca809bac0295afdd01c9cd 288 Gene3D G3DSA:3.10.450.50 150 284 2.4E-17 T 28-03-2018 CU254_RS29720 988f1c58fcca809bac0295afdd01c9cd 288 SUPERFAMILY SSF54427 170 283 3.7E-14 T 28-03-2018 IPR032710 NTF2-like domain CU254_RS29720 988f1c58fcca809bac0295afdd01c9cd 288 Gene3D G3DSA:1.10.10.10 72 149 9.8E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS29720 988f1c58fcca809bac0295afdd01c9cd 288 Pfam PF08281 Sigma-70, region 4 108 159 1.1E-13 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS29720 988f1c58fcca809bac0295afdd01c9cd 288 Gene3D G3DSA:1.10.1740.10 2 71 5.4E-11 T 28-03-2018 CU254_RS29720 988f1c58fcca809bac0295afdd01c9cd 288 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 9 160 1.6E-15 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS29720 988f1c58fcca809bac0295afdd01c9cd 288 SUPERFAMILY SSF88946 8 68 2.24E-10 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS29720 988f1c58fcca809bac0295afdd01c9cd 288 Pfam PF04542 Sigma-70 region 2 11 69 4.1E-13 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS29720 988f1c58fcca809bac0295afdd01c9cd 288 Pfam PF12680 SnoaL-like domain 177 273 9.7E-7 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CU254_RS01310 391e0063188cbdf72509bcdb08dba5a3 359 SUPERFAMILY SSF53756 2 350 2.14E-65 T 28-03-2018 CU254_RS01310 391e0063188cbdf72509bcdb08dba5a3 359 Pfam PF00534 Glycosyl transferases group 1 179 330 7.2E-20 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CU254_RS01310 391e0063188cbdf72509bcdb08dba5a3 359 Pfam PF13439 Glycosyltransferase Family 4 1 165 4.8E-23 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CU254_RS01310 391e0063188cbdf72509bcdb08dba5a3 359 Gene3D G3DSA:3.40.50.2000 1 173 3.8E-22 T 28-03-2018 CU254_RS01310 391e0063188cbdf72509bcdb08dba5a3 359 Gene3D G3DSA:3.40.50.2000 174 334 7.9E-32 T 28-03-2018 CU254_RS18965 5a119ac03d8fd4b42a271b32efb606ec 158 Pfam PF01638 HxlR-like helix-turn-helix 33 116 2.5E-19 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type CU254_RS18965 5a119ac03d8fd4b42a271b32efb606ec 158 Gene3D G3DSA:1.10.10.10 15 157 6.4E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS18965 5a119ac03d8fd4b42a271b32efb606ec 158 SUPERFAMILY SSF46785 22 131 3.88E-34 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS32280 9e2b724d260540b30d608341a8f9d8db 474 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 207 213 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CU254_RS32280 9e2b724d260540b30d608341a8f9d8db 474 Gene3D G3DSA:3.40.50.150 91 310 3.4E-18 T 28-03-2018 CU254_RS32280 9e2b724d260540b30d608341a8f9d8db 474 Pfam PF01861 Protein of unknown function DUF43 107 281 1.1E-25 T 28-03-2018 IPR002723 N(4)-bis(aminopropyl)spermidine synthase, C-terminal CU254_RS32280 9e2b724d260540b30d608341a8f9d8db 474 SUPERFAMILY SSF53335 152 274 3.23E-7 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS34530 b28dd12d4de69db121328c3d479617d9 245 SUPERFAMILY SSF53335 22 131 4.22E-12 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS34530 b28dd12d4de69db121328c3d479617d9 245 Gene3D G3DSA:3.40.50.150 18 230 2.1E-11 T 28-03-2018 CU254_RS34530 b28dd12d4de69db121328c3d479617d9 245 Pfam PF13649 Methyltransferase domain 42 128 2.9E-8 T 28-03-2018 CU254_RS28060 1212fcf82afbee0bb22ab8406f450b00 461 PIRSF PIRSF006060 7 461 1.2E-93 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CU254_RS28060 1212fcf82afbee0bb22ab8406f450b00 461 Pfam PF13520 Amino acid permease 23 425 1.3E-57 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CU254_RS05545 14616fdeff5ba7b384adad6f8decb546 257 SUPERFAMILY SSF49329 93 252 1.57E-34 T 28-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CU254_RS05545 14616fdeff5ba7b384adad6f8decb546 257 Gene3D G3DSA:2.60.40.200 85 253 1.1E-27 T 28-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CU254_RS05545 14616fdeff5ba7b384adad6f8decb546 257 Pfam PF00080 Copper/zinc superoxide dismutase (SODC) 99 251 8.7E-27 T 28-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CU254_RS03180 11bb4f4ed68f6bc2c072d883f324512b 502 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 4 499 3.0E-226 T 28-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 CU254_RS03180 11bb4f4ed68f6bc2c072d883f324512b 502 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 254 5.9E-76 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CU254_RS03180 11bb4f4ed68f6bc2c072d883f324512b 502 SUPERFAMILY SSF53067 257 500 2.65E-84 T 28-03-2018 CU254_RS03180 11bb4f4ed68f6bc2c072d883f324512b 502 PIRSF PIRSF000538 2 502 6.3E-174 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CU254_RS03180 11bb4f4ed68f6bc2c072d883f324512b 502 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 263 453 5.5E-64 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CU254_RS03180 11bb4f4ed68f6bc2c072d883f324512b 502 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 365 385 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CU254_RS03180 11bb4f4ed68f6bc2c072d883f324512b 502 SUPERFAMILY SSF53067 4 257 2.88E-89 T 28-03-2018 CU254_RS03180 11bb4f4ed68f6bc2c072d883f324512b 502 Hamap MF_00186 Glycerol kinase [glpK]. 2 500 55.96 T 28-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 CU254_RS03180 11bb4f4ed68f6bc2c072d883f324512b 502 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 135 147 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CU254_RS03180 11bb4f4ed68f6bc2c072d883f324512b 502 Gene3D G3DSA:3.30.420.40 252 502 1.3E-79 T 28-03-2018 CU254_RS03180 11bb4f4ed68f6bc2c072d883f324512b 502 Gene3D G3DSA:3.30.420.40 1 251 5.1E-90 T 28-03-2018 CU254_RS38185 efa51c3453b1239fdbc4e7c9e51f3b39 364 Gene3D G3DSA:1.50.10.20 31 364 7.7E-42 T 28-03-2018 CU254_RS38185 efa51c3453b1239fdbc4e7c9e51f3b39 364 Pfam PF03663 Glycosyl hydrolase family 76 70 337 4.0E-24 T 28-03-2018 IPR005198 Glycoside hydrolase, family 76 KEGG: 00052+3.2.1.10|KEGG: 00500+3.2.1.10 CU254_RS38185 efa51c3453b1239fdbc4e7c9e51f3b39 364 SUPERFAMILY SSF48208 58 356 5.53E-25 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CU254_RS23310 6b36ecf21841605da5a6c4fe20d272af 241 SUPERFAMILY SSF52317 5 238 6.11E-61 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS23310 6b36ecf21841605da5a6c4fe20d272af 241 Gene3D G3DSA:3.40.50.880 1 241 9.6E-39 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS23310 6b36ecf21841605da5a6c4fe20d272af 241 Pfam PF01965 DJ-1/PfpI family 31 236 5.1E-11 T 28-03-2018 IPR002818 DJ-1/PfpI CU254_RS18720 3b02a22e50476bae5e61dacf913c51bf 483 Pfam PF01425 Amidase 24 464 3.0E-108 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS18720 3b02a22e50476bae5e61dacf913c51bf 483 ProSitePatterns PS00571 Amidases signature. 151 182 - T 28-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CU254_RS18720 3b02a22e50476bae5e61dacf913c51bf 483 SUPERFAMILY SSF75304 6 476 1.3E-124 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS18720 3b02a22e50476bae5e61dacf913c51bf 483 Gene3D G3DSA:3.90.1300.10 4 483 4.1E-131 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS24165 6704598125343148f334b6892ff57376 264 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 102 122 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CU254_RS24165 6704598125343148f334b6892ff57376 264 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 263 1.7E-64 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CU254_RS24165 6704598125343148f334b6892ff57376 264 SUPERFAMILY SSF52096 7 262 1.44E-82 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS24165 6704598125343148f334b6892ff57376 264 Gene3D G3DSA:1.10.12.10 217 264 1.8E-14 T 28-03-2018 IPR014748 Crontonase, C-terminal CU254_RS24165 6704598125343148f334b6892ff57376 264 Gene3D G3DSA:3.90.226.10 2 216 6.0E-69 T 28-03-2018 CU254_RS33075 66a066dc203cce3ae7d7f1c20b2536a8 211 SMART SM00421 148 205 4.3E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS33075 66a066dc203cce3ae7d7f1c20b2536a8 211 Gene3D G3DSA:1.10.10.10 108 211 1.3E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS33075 66a066dc203cce3ae7d7f1c20b2536a8 211 Pfam PF00196 Bacterial regulatory proteins, luxR family 151 205 1.3E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS33075 66a066dc203cce3ae7d7f1c20b2536a8 211 SUPERFAMILY SSF46894 136 210 1.77E-17 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS33075 66a066dc203cce3ae7d7f1c20b2536a8 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 2.0E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS33075 66a066dc203cce3ae7d7f1c20b2536a8 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 2.0E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS33075 66a066dc203cce3ae7d7f1c20b2536a8 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 2.0E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS20975 db84a90d38e12cf3f9c433d1f09d3a78 214 Pfam PF01895 PhoU domain 122 203 4.1E-7 T 28-03-2018 IPR026022 PhoU domain CU254_RS20975 db84a90d38e12cf3f9c433d1f09d3a78 214 Pfam PF01895 PhoU domain 18 101 3.3E-14 T 28-03-2018 IPR026022 PhoU domain CU254_RS20975 db84a90d38e12cf3f9c433d1f09d3a78 214 Gene3D G3DSA:1.20.58.220 114 211 1.2E-8 T 28-03-2018 CU254_RS20975 db84a90d38e12cf3f9c433d1f09d3a78 214 Gene3D G3DSA:1.20.58.220 1 107 4.3E-19 T 28-03-2018 CU254_RS20975 db84a90d38e12cf3f9c433d1f09d3a78 214 PIRSF PIRSF003107 1 213 1.2E-42 T 28-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 CU254_RS20975 db84a90d38e12cf3f9c433d1f09d3a78 214 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 4 211 1.3E-38 T 28-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 CU254_RS20975 db84a90d38e12cf3f9c433d1f09d3a78 214 SUPERFAMILY SSF109755 2 212 1.78E-42 T 28-03-2018 CU254_RS15175 ff23cc64298ff8039c5934795d335378 89 Pfam PF08940 Domain of unknown function (DUF1918) 1 58 1.5E-23 T 28-03-2018 IPR015035 Domain of unknown function DUF1918 CU254_RS15175 ff23cc64298ff8039c5934795d335378 89 SUPERFAMILY SSF50118 1 75 9.81E-24 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CU254_RS33420 312b5ebd2458c6bea8cc7c13ca7cf3dc 408 Pfam PF07690 Major Facilitator Superfamily 14 317 3.0E-29 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS33420 312b5ebd2458c6bea8cc7c13ca7cf3dc 408 SUPERFAMILY SSF103473 3 399 1.96E-52 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS33420 312b5ebd2458c6bea8cc7c13ca7cf3dc 408 Gene3D G3DSA:1.20.1250.20 1 197 5.1E-23 T 28-03-2018 CU254_RS33420 312b5ebd2458c6bea8cc7c13ca7cf3dc 408 Gene3D G3DSA:1.20.1250.20 198 406 2.5E-21 T 28-03-2018 CU254_RS18150 6d8b1d111c0f42201c7ed488caee5e71 87 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 5 87 3.0E-21 T 28-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 CU254_RS18150 6d8b1d111c0f42201c7ed488caee5e71 87 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 1 87 17.413 T 28-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 CU254_RS18150 6d8b1d111c0f42201c7ed488caee5e71 87 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 11 85 4.5E-5 T 28-03-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 CU254_RS18150 6d8b1d111c0f42201c7ed488caee5e71 87 Gene3D G3DSA:1.10.287.1080 1 87 1.5E-14 T 28-03-2018 CU254_RS18150 6d8b1d111c0f42201c7ed488caee5e71 87 SUPERFAMILY SSF101386 2 87 1.83E-20 T 28-03-2018 CU254_RS27120 e339a3687b89d53c8488c5d6bbb3d8f4 289 SUPERFAMILY SSF53335 10 262 2.39E-38 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS27120 e339a3687b89d53c8488c5d6bbb3d8f4 289 Pfam PF04672 S-adenosyl methyltransferase 10 289 1.3E-70 T 28-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CU254_RS27120 e339a3687b89d53c8488c5d6bbb3d8f4 289 PIRSF PIRSF017393 1 289 2.5E-75 T 28-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CU254_RS27120 e339a3687b89d53c8488c5d6bbb3d8f4 289 Gene3D G3DSA:3.40.50.150 2 289 8.3E-43 T 28-03-2018 CU254_RS20850 65505f1a946bf8cc04ac260883048c4a 345 SUPERFAMILY SSF47413 5 62 3.0E-10 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS20850 65505f1a946bf8cc04ac260883048c4a 345 Gene3D G3DSA:1.10.260.40 6 60 1.9E-14 T 28-03-2018 CU254_RS20850 65505f1a946bf8cc04ac260883048c4a 345 Gene3D G3DSA:3.40.50.2300 170 335 9.4E-47 T 28-03-2018 CU254_RS20850 65505f1a946bf8cc04ac260883048c4a 345 Pfam PF13377 Periplasmic binding protein-like domain 171 332 5.2E-36 T 28-03-2018 CU254_RS20850 65505f1a946bf8cc04ac260883048c4a 345 Pfam PF00356 Bacterial regulatory proteins, lacI family 7 49 3.5E-8 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CU254_RS20850 65505f1a946bf8cc04ac260883048c4a 345 SUPERFAMILY SSF53822 65 334 1.96E-67 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CU254_RS20850 65505f1a946bf8cc04ac260883048c4a 345 SMART SM00354 5 74 3.1E-9 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CU254_RS20850 65505f1a946bf8cc04ac260883048c4a 345 Gene3D G3DSA:3.40.50.2300 61 169 1.1E-27 T 28-03-2018 CU254_RS26095 afb3eb72cea9ca8f56293fadd14eb440 428 Gene3D G3DSA:3.90.1150.10 8 177 1.7E-31 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS26095 afb3eb72cea9ca8f56293fadd14eb440 428 SUPERFAMILY SSF53383 18 418 2.02E-85 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS26095 afb3eb72cea9ca8f56293fadd14eb440 428 Gene3D G3DSA:3.90.1150.10 311 425 0.0034 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS26095 afb3eb72cea9ca8f56293fadd14eb440 428 Pfam PF00202 Aminotransferase class-III 45 399 4.7E-50 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CU254_RS26095 afb3eb72cea9ca8f56293fadd14eb440 428 Gene3D G3DSA:3.40.640.10 178 310 3.2E-35 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS27720 baac70cbde8db7cf0fce870d49092340 306 SUPERFAMILY SSF103481 57 151 1.83E-7 T 28-03-2018 CU254_RS27720 baac70cbde8db7cf0fce870d49092340 306 SUPERFAMILY SSF103481 200 294 5.36E-12 T 28-03-2018 CU254_RS27720 baac70cbde8db7cf0fce870d49092340 306 Pfam PF00892 EamA-like transporter family 164 293 4.6E-18 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CU254_RS27720 baac70cbde8db7cf0fce870d49092340 306 Pfam PF00892 EamA-like transporter family 19 150 8.3E-9 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CU254_RS40620 b88331673537ddd4a839f1b67a935c8f 253 Pfam PF01925 Sulfite exporter TauE/SafE 9 249 1.6E-41 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CU254_RS16430 43653f7a800343ef104ccf0383416ddd 261 SUPERFAMILY SSF51735 1 260 7.58E-67 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS16430 43653f7a800343ef104ccf0383416ddd 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 2.2E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS16430 43653f7a800343ef104ccf0383416ddd 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 2.2E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS16430 43653f7a800343ef104ccf0383416ddd 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 2.2E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS16430 43653f7a800343ef104ccf0383416ddd 261 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 198 2.1E-5 T 28-03-2018 CU254_RS16430 43653f7a800343ef104ccf0383416ddd 261 Pfam PF00106 short chain dehydrogenase 8 197 3.2E-49 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS16430 43653f7a800343ef104ccf0383416ddd 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 2.6E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS16430 43653f7a800343ef104ccf0383416ddd 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.6E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS16430 43653f7a800343ef104ccf0383416ddd 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 2.6E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS16430 43653f7a800343ef104ccf0383416ddd 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 2.6E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS16430 43653f7a800343ef104ccf0383416ddd 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 223 243 2.6E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS16430 43653f7a800343ef104ccf0383416ddd 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 2.6E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS16430 43653f7a800343ef104ccf0383416ddd 261 Gene3D G3DSA:3.40.50.720 53 261 4.9E-53 T 28-03-2018 CU254_RS16430 43653f7a800343ef104ccf0383416ddd 261 Gene3D G3DSA:3.40.50.10090 2 52 4.8E-11 T 28-03-2018 CU254_RS16430 43653f7a800343ef104ccf0383416ddd 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS17330 a3650fb86d51b2726ce047fc4b5b3535 286 Gene3D G3DSA:3.40.50.150 11 267 1.1E-36 T 28-03-2018 CU254_RS17330 a3650fb86d51b2726ce047fc4b5b3535 286 SUPERFAMILY SSF53335 14 219 1.94E-36 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS17330 a3650fb86d51b2726ce047fc4b5b3535 286 Pfam PF13649 Methyltransferase domain 56 150 1.1E-17 T 28-03-2018 CU254_RS14365 11250941a3825383141e142e3fe5e7f9 33 TIGRFAM TIGR03969 mycofactocin: mycofactocin precursor 12 33 8.2E-14 T 28-03-2018 IPR023988 Mycofactocin CU254_RS37240 cda281f99626f8339cd65e02e313c1be 86 Gene3D G3DSA:3.40.50.720 4 84 1.1E-4 T 28-03-2018 CU254_RS41325 a8ecc00281725e4ff257ac7b6c823a25 414 Pfam PF03259 Roadblock/LC7 domain 289 368 2.8E-6 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain CU254_RS41325 a8ecc00281725e4ff257ac7b6c823a25 414 SUPERFAMILY SSF103196 285 402 6.8E-7 T 28-03-2018 CU254_RS41325 a8ecc00281725e4ff257ac7b6c823a25 414 Gene3D G3DSA:3.30.450.30 272 406 2.3E-16 T 28-03-2018 CU254_RS39135 9e56027b1e032c6c90dbbd838154e485 168 Pfam PF00293 NUDIX domain 32 155 7.7E-25 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CU254_RS39135 9e56027b1e032c6c90dbbd838154e485 168 SUPERFAMILY SSF55811 17 162 1.14E-33 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CU254_RS39135 9e56027b1e032c6c90dbbd838154e485 168 Gene3D G3DSA:3.90.79.10 28 164 2.6E-32 T 28-03-2018 CU254_RS39135 9e56027b1e032c6c90dbbd838154e485 168 ProSitePatterns PS00893 Nudix box signature. 64 85 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CU254_RS39135 9e56027b1e032c6c90dbbd838154e485 168 PRINTS PR00502 NUDIX hydrolase family signature 59 73 9.9E-9 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CU254_RS39135 9e56027b1e032c6c90dbbd838154e485 168 PRINTS PR00502 NUDIX hydrolase family signature 73 88 9.9E-9 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CU254_RS17090 c9225cb2875911a7e7f0d7e4876c5fc9 418 Gene3D G3DSA:3.40.50.2000 1 231 4.4E-35 T 28-03-2018 CU254_RS17090 c9225cb2875911a7e7f0d7e4876c5fc9 418 TIGRFAM TIGR04516 glycosyl_450act: glycosyltransferase, activator-dependent family 1 414 4.1E-159 T 28-03-2018 IPR030953 Glycosyltransferase, activator-dependent family GO:0016757 CU254_RS17090 c9225cb2875911a7e7f0d7e4876c5fc9 418 Pfam PF06722 Protein of unknown function (DUF1205) 207 301 5.9E-24 T 28-03-2018 IPR010610 Domain of unknown function DUF1205 CU254_RS17090 c9225cb2875911a7e7f0d7e4876c5fc9 418 SUPERFAMILY SSF53756 1 56 2.27E-82 T 28-03-2018 CU254_RS17090 c9225cb2875911a7e7f0d7e4876c5fc9 418 SUPERFAMILY SSF53756 84 415 2.27E-82 T 28-03-2018 CU254_RS17090 c9225cb2875911a7e7f0d7e4876c5fc9 418 Gene3D G3DSA:3.40.50.2000 232 399 8.9E-40 T 28-03-2018 CU254_RS14210 21d1b8aa01db573668d06f399a24f843 301 Pfam PF13354 Beta-lactamase enzyme family 28 267 1.8E-38 T 28-03-2018 CU254_RS14210 21d1b8aa01db573668d06f399a24f843 301 SUPERFAMILY SSF56601 184 273 4.98E-29 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CU254_RS14210 21d1b8aa01db573668d06f399a24f843 301 SUPERFAMILY SSF56601 5 152 4.98E-29 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CU254_RS14210 21d1b8aa01db573668d06f399a24f843 301 Gene3D G3DSA:3.40.710.10 1 299 4.0E-26 T 28-03-2018 CU254_RS31935 f4aa9354f609ea2cd754783db512825e 538 SUPERFAMILY SSF52518 352 522 3.3E-39 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS31935 f4aa9354f609ea2cd754783db512825e 538 Gene3D G3DSA:3.40.50.1220 179 342 1.9E-33 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CU254_RS31935 f4aa9354f609ea2cd754783db512825e 538 Gene3D G3DSA:3.40.50.970 343 530 3.2E-29 T 28-03-2018 CU254_RS31935 f4aa9354f609ea2cd754783db512825e 538 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 186 316 2.5E-28 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CU254_RS31935 f4aa9354f609ea2cd754783db512825e 538 SUPERFAMILY SSF52518 3 175 1.27E-45 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CU254_RS31935 f4aa9354f609ea2cd754783db512825e 538 SUPERFAMILY SSF52467 151 322 8.18E-35 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CU254_RS31935 f4aa9354f609ea2cd754783db512825e 538 Gene3D G3DSA:3.40.50.970 1 178 1.0E-48 T 28-03-2018 CU254_RS31935 f4aa9354f609ea2cd754783db512825e 538 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 376 519 4.2E-26 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CU254_RS31935 f4aa9354f609ea2cd754783db512825e 538 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 3 166 1.2E-52 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CU254_RS26625 414a93483e943b7b0643f167702b2631 440 Gene3D G3DSA:3.40.50.1820 30 295 5.1E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS26625 414a93483e943b7b0643f167702b2631 440 SUPERFAMILY SSF53474 29 289 8.03E-31 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS19640 5f6154c3e0f47ad54a3ad180944e8ffd 305 SUPERFAMILY SSF51430 2 292 5.89E-86 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS19640 5f6154c3e0f47ad54a3ad180944e8ffd 305 Gene3D G3DSA:3.20.20.100 1 296 5.8E-80 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS19640 5f6154c3e0f47ad54a3ad180944e8ffd 305 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 121 138 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CU254_RS19640 5f6154c3e0f47ad54a3ad180944e8ffd 305 Pfam PF00248 Aldo/keto reductase family 1 290 3.8E-65 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS32710 c134c49c4168645e895b215f3cb683f5 545 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 79 247 3.2E-13 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS32710 c134c49c4168645e895b215f3cb683f5 545 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 372 528 6.9E-8 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS32710 c134c49c4168645e895b215f3cb683f5 545 Gene3D G3DSA:1.10.3720.10 274 540 4.8E-23 T 28-03-2018 CU254_RS32710 c134c49c4168645e895b215f3cb683f5 545 Gene3D G3DSA:1.10.3720.10 15 258 3.9E-35 T 28-03-2018 CU254_RS32710 c134c49c4168645e895b215f3cb683f5 545 SUPERFAMILY SSF161098 271 532 2.88E-32 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS32710 c134c49c4168645e895b215f3cb683f5 545 SUPERFAMILY SSF161098 17 253 2.4E-42 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS12135 895d1fc5cca701514d305960cb4cd849 282 Gene3D G3DSA:1.20.1080.10 10 269 2.7E-63 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CU254_RS12135 895d1fc5cca701514d305960cb4cd849 282 ProSitePatterns PS01006 Formate and nitrite transporters signature 2. 169 179 - T 28-03-2018 IPR024002 Formate/nitrite transporter, conserved site CU254_RS12135 895d1fc5cca701514d305960cb4cd849 282 Pfam PF01226 Formate/nitrite transporter 23 258 7.2E-59 T 28-03-2018 IPR000292 Formate/nitrite transporter GO:0005215|GO:0006810|GO:0016020 CU254_RS13835 336d5dec3c9706be39b66550b3fa2940 288 SUPERFAMILY SSF103481 196 285 3.14E-11 T 28-03-2018 CU254_RS13835 336d5dec3c9706be39b66550b3fa2940 288 SUPERFAMILY SSF103481 52 139 3.79E-5 T 28-03-2018 CU254_RS13835 336d5dec3c9706be39b66550b3fa2940 288 Pfam PF00892 EamA-like transporter family 150 278 9.3E-14 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CU254_RS29580 f9a834429f9f3be456bcab84803942d2 502 SUPERFAMILY SSF53720 8 488 2.09E-165 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CU254_RS29580 f9a834429f9f3be456bcab84803942d2 502 Gene3D G3DSA:3.40.605.10 2 274 1.7E-93 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CU254_RS29580 f9a834429f9f3be456bcab84803942d2 502 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 258 265 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CU254_RS29580 f9a834429f9f3be456bcab84803942d2 502 TIGRFAM TIGR02299 HpaE: 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase 14 496 1.1E-198 T 28-03-2018 IPR011985 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase GO:0018480|GO:1901023 CU254_RS29580 f9a834429f9f3be456bcab84803942d2 502 Gene3D G3DSA:3.40.309.10 275 468 1.1E-73 T 28-03-2018 CU254_RS29580 f9a834429f9f3be456bcab84803942d2 502 Pfam PF00171 Aldehyde dehydrogenase family 27 483 9.4E-172 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CU254_RS29580 f9a834429f9f3be456bcab84803942d2 502 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 286 297 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CU254_RS18520 ba96837e81c8cc99eba1780376efad70 167 Gene3D G3DSA:1.10.150.20 114 166 5.4E-7 T 28-03-2018 CU254_RS18520 ba96837e81c8cc99eba1780376efad70 167 Gene3D G3DSA:3.30.1460.30 3 95 1.0E-4 T 28-03-2018 CU254_RS10565 d32da3d6d366f5c7f2fed372af54fe12 387 Gene3D G3DSA:3.40.47.10 216 380 2.5E-9 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS10565 d32da3d6d366f5c7f2fed372af54fe12 387 Gene3D G3DSA:3.40.47.10 3 215 2.9E-16 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS10565 d32da3d6d366f5c7f2fed372af54fe12 387 SUPERFAMILY SSF53901 11 223 1.33E-20 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS10565 d32da3d6d366f5c7f2fed372af54fe12 387 SUPERFAMILY SSF53901 247 371 4.61E-17 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS10565 d32da3d6d366f5c7f2fed372af54fe12 387 PIRSF PIRSF000429 164 380 1.7E-11 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CU254_RS10565 d32da3d6d366f5c7f2fed372af54fe12 387 PIRSF PIRSF000429 1 126 2.6E-6 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CU254_RS37325 6155650446890cdcc6d2c0786aac2fc5 300 SMART SM01130 9 298 2.8E-56 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CU254_RS37325 6155650446890cdcc6d2c0786aac2fc5 300 Gene3D G3DSA:3.20.20.70 4 300 2.4E-65 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS37325 6155650446890cdcc6d2c0786aac2fc5 300 PIRSF PIRSF001365 5 300 2.8E-58 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CU254_RS37325 6155650446890cdcc6d2c0786aac2fc5 300 SUPERFAMILY SSF51569 8 298 6.8E-61 T 28-03-2018 CU254_RS37325 6155650446890cdcc6d2c0786aac2fc5 300 Pfam PF00701 Dihydrodipicolinate synthetase family 10 295 1.7E-41 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CU254_RS37035 f37e1ce1ff97074191746843b9573153 514 Gene3D G3DSA:3.10.105.10 281 486 6.2E-46 T 28-03-2018 CU254_RS37035 f37e1ce1ff97074191746843b9573153 514 Gene3D G3DSA:3.90.76.10 8 173 1.7E-34 T 28-03-2018 CU254_RS37035 f37e1ce1ff97074191746843b9573153 514 Gene3D G3DSA:3.40.190.10 182 280 5.4E-22 T 28-03-2018 CU254_RS37035 f37e1ce1ff97074191746843b9573153 514 PIRSF PIRSF002741 1 513 1.4E-82 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CU254_RS37035 f37e1ce1ff97074191746843b9573153 514 SUPERFAMILY SSF53850 2 513 3.8E-109 T 28-03-2018 CU254_RS37035 f37e1ce1ff97074191746843b9573153 514 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 43 433 2.3E-78 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CU254_RS03865 b450b1c07d1d911e992cc2dd0f976524 64 Pfam PF04024 PspC domain 8 63 2.8E-17 T 28-03-2018 IPR007168 Phage shock protein, PspC, N-terminal CU254_RS40200 8e82e47d443eae053debae9335b645d2 394 SUPERFAMILY SSF51905 4 282 2.59E-49 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS40200 8e82e47d443eae053debae9335b645d2 394 Gene3D G3DSA:3.50.50.60 1 57 1.2E-8 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS40200 8e82e47d443eae053debae9335b645d2 394 Gene3D G3DSA:3.30.9.10 158 347 1.0E-30 T 28-03-2018 CU254_RS40200 8e82e47d443eae053debae9335b645d2 394 Pfam PF01266 FAD dependent oxidoreductase 4 391 1.0E-66 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CU254_RS40200 8e82e47d443eae053debae9335b645d2 394 Gene3D G3DSA:3.30.9.10 84 157 1.4E-10 T 28-03-2018 CU254_RS15570 8450c2795c81b1e378934821bba83fb3 311 Pfam PF01758 Sodium Bile acid symporter family 36 201 8.8E-13 T 28-03-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 CU254_RS08650 39f3f5f3a6b481dc31e7808336a76984 478 Pfam PF00324 Amino acid permease 30 469 5.8E-103 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CU254_RS08650 39f3f5f3a6b481dc31e7808336a76984 478 ProSitePatterns PS00218 Amino acid permeases signature. 55 85 - T 28-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CU254_RS08650 39f3f5f3a6b481dc31e7808336a76984 478 PIRSF PIRSF006060 16 477 6.0E-59 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CU254_RS26425 694efdcc768fa54c9c61364e8b77e190 109 Pfam PF04505 Interferon-induced transmembrane protein 24 88 1.1E-19 T 28-03-2018 IPR007593 CD225/Dispanin family GO:0009607|GO:0016021 CU254_RS07225 d9db5c0cf7a481171b1053bb6a0854f8 338 SUPERFAMILY SSF50985 58 330 2.7E-39 T 28-03-2018 IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II CU254_RS07225 d9db5c0cf7a481171b1053bb6a0854f8 338 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 275 304 6.0E-7 T 28-03-2018 CU254_RS07225 d9db5c0cf7a481171b1053bb6a0854f8 338 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 197 225 8.8E-7 T 28-03-2018 CU254_RS07225 d9db5c0cf7a481171b1053bb6a0854f8 338 Pfam PF13540 Regulator of chromosome condensation (RCC1) repeat 236 264 2.0E-6 T 28-03-2018 CU254_RS07225 d9db5c0cf7a481171b1053bb6a0854f8 338 Gene3D G3DSA:2.130.10.30 48 226 2.5E-28 T 28-03-2018 CU254_RS07225 d9db5c0cf7a481171b1053bb6a0854f8 338 Gene3D G3DSA:3.10.100.10 227 263 4.4E-7 T 28-03-2018 IPR016186 C-type lectin-like/link domain CU254_RS07225 d9db5c0cf7a481171b1053bb6a0854f8 338 Gene3D G3DSA:3.10.100.10 264 307 1.7E-10 T 28-03-2018 IPR016186 C-type lectin-like/link domain CU254_RS39680 7c8c60a61b690e55df43e0ea1f7c49cb 433 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 14 47 - T 28-03-2018 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 CU254_RS39680 7c8c60a61b690e55df43e0ea1f7c49cb 433 TIGRFAM TIGR01679 bact_FAD_ox: FAD-linked oxidoreductase 3 431 2.6E-120 T 28-03-2018 CU254_RS39680 7c8c60a61b690e55df43e0ea1f7c49cb 433 PIRSF PIRSF000136 1 433 3.2E-113 T 28-03-2018 IPR010031 L-gulonolactone/D-arabinono-1,4-lactone oxidase GO:0016899|GO:0055114 CU254_RS39680 7c8c60a61b690e55df43e0ea1f7c49cb 433 Gene3D G3DSA:3.40.462.10 180 397 4.0E-49 T 28-03-2018 IPR016170 Vanillyl-alcohol oxidase/Cytokinin dehydrogenase C-terminal domain CU254_RS39680 7c8c60a61b690e55df43e0ea1f7c49cb 433 Pfam PF04030 D-arabinono-1,4-lactone oxidase 173 429 2.4E-71 T 28-03-2018 IPR007173 D-arabinono-1,4-lactone oxidase GO:0003885|GO:0016020|GO:0055114 CU254_RS39680 7c8c60a61b690e55df43e0ea1f7c49cb 433 Pfam PF01565 FAD binding domain 14 148 3.7E-24 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CU254_RS39680 7c8c60a61b690e55df43e0ea1f7c49cb 433 Gene3D G3DSA:3.30.465.10 68 179 1.3E-28 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CU254_RS39680 7c8c60a61b690e55df43e0ea1f7c49cb 433 Gene3D G3DSA:3.30.43.10 1 66 1.5E-13 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CU254_RS39680 7c8c60a61b690e55df43e0ea1f7c49cb 433 SUPERFAMILY SSF56176 2 179 5.14E-46 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CU254_RS11510 8931161e5246e33c0cd83c722a1f1557 89 Gene3D G3DSA:3.90.940.10 15 89 9.2E-20 T 28-03-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CU254_RS11510 8931161e5246e33c0cd83c722a1f1557 89 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 14 84 2.4E-26 T 28-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CU254_RS11510 8931161e5246e33c0cd83c722a1f1557 89 Pfam PF01192 RNA polymerase Rpb6 21 83 1.3E-14 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CU254_RS11510 8931161e5246e33c0cd83c722a1f1557 89 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 14 86 14.179 T 28-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CU254_RS11510 8931161e5246e33c0cd83c722a1f1557 89 SUPERFAMILY SSF63562 14 85 9.24E-23 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CU254_RS11510 8931161e5246e33c0cd83c722a1f1557 89 SMART SM01409 21 85 1.7E-13 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CU254_RS24050 823e259561a1a754fed87291440a83ea 751 SUPERFAMILY SSF53850 493 618 2.82E-7 T 28-03-2018 CU254_RS24050 823e259561a1a754fed87291440a83ea 751 Gene3D G3DSA:3.40.190.10 413 551 5.4E-5 T 28-03-2018 CU254_RS27780 47860227d536cadfe001df102288ddbd 400 SUPERFAMILY SSF103473 12 389 3.14E-39 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS27780 47860227d536cadfe001df102288ddbd 400 Pfam PF07690 Major Facilitator Superfamily 17 347 8.0E-24 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS27780 47860227d536cadfe001df102288ddbd 400 Gene3D G3DSA:1.20.1250.20 3 192 2.4E-17 T 28-03-2018 CU254_RS27780 47860227d536cadfe001df102288ddbd 400 Gene3D G3DSA:1.20.1250.20 193 396 2.4E-18 T 28-03-2018 CU254_RS42065 9e022af93d3b4c3263b354938a264b7b 411 SUPERFAMILY SSF102114 121 175 1.73E-6 T 28-03-2018 CU254_RS42065 9e022af93d3b4c3263b354938a264b7b 411 Gene3D G3DSA:3.20.20.70 101 362 6.5E-10 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS27505 8570d08c43a4be3bed2aa5f41c860bd2 855 SUPERFAMILY SSF63737 6 202 3.01E-39 T 28-03-2018 CU254_RS27505 8570d08c43a4be3bed2aa5f41c860bd2 855 Gene3D G3DSA:2.60.40.1730 17 203 7.3E-36 T 28-03-2018 CU254_RS27505 8570d08c43a4be3bed2aa5f41c860bd2 855 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 268 278 4.3E-22 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CU254_RS27505 8570d08c43a4be3bed2aa5f41c860bd2 855 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 137 152 4.3E-22 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CU254_RS27505 8570d08c43a4be3bed2aa5f41c860bd2 855 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 302 317 4.3E-22 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CU254_RS27505 8570d08c43a4be3bed2aa5f41c860bd2 855 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 185 200 4.3E-22 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CU254_RS27505 8570d08c43a4be3bed2aa5f41c860bd2 855 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 321 333 4.3E-22 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CU254_RS27505 8570d08c43a4be3bed2aa5f41c860bd2 855 Pfam PF11838 ERAP1-like C-terminal domain 534 842 7.4E-59 T 28-03-2018 IPR024571 ERAP1-like C-terminal domain CU254_RS27505 8570d08c43a4be3bed2aa5f41c860bd2 855 SUPERFAMILY SSF55486 213 459 4.15E-77 T 28-03-2018 CU254_RS27505 8570d08c43a4be3bed2aa5f41c860bd2 855 TIGRFAM TIGR02412 pepN_strep_liv: aminopeptidase N 5 850 0.0 T 28-03-2018 IPR012778 Peptidase M1, aminopeptidase GO:0004177|GO:0006508 KEGG: 00480+3.4.11.2|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112 CU254_RS27505 8570d08c43a4be3bed2aa5f41c860bd2 855 Pfam PF01433 Peptidase family M1 domain 217 450 2.5E-57 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CU254_RS27505 8570d08c43a4be3bed2aa5f41c860bd2 855 Gene3D G3DSA:1.10.390.10 288 454 5.5E-45 T 28-03-2018 CU254_RS05600 8f49bcbb418e4e2e4976665278958354 392 SUPERFAMILY SSF103473 3 375 5.23E-57 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS05600 8f49bcbb418e4e2e4976665278958354 392 Gene3D G3DSA:1.20.1250.20 192 381 3.2E-16 T 28-03-2018 CU254_RS05600 8f49bcbb418e4e2e4976665278958354 392 Pfam PF07690 Major Facilitator Superfamily 8 338 4.2E-41 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS05600 8f49bcbb418e4e2e4976665278958354 392 Gene3D G3DSA:1.20.1250.20 3 191 3.7E-29 T 28-03-2018 CU254_RS38585 9bc50dd3a71297a7be1ce5a1aa63d381 190 Gene3D G3DSA:1.10.10.60 4 43 1.0E-14 T 28-03-2018 CU254_RS38585 9bc50dd3a71297a7be1ce5a1aa63d381 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 2.1E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS38585 9bc50dd3a71297a7be1ce5a1aa63d381 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 2.1E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS38585 9bc50dd3a71297a7be1ce5a1aa63d381 190 SUPERFAMILY SSF46689 3 64 4.03E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS38585 9bc50dd3a71297a7be1ce5a1aa63d381 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 55 2.9E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS38585 9bc50dd3a71297a7be1ce5a1aa63d381 190 Gene3D G3DSA:1.10.10.60 44 142 7.9E-9 T 28-03-2018 CU254_RS25050 3ea6dc87afe14cb635ccf7c9089a88b6 399 Pfam PF04209 homogentisate 1,2-dioxygenase 9 380 2.0E-16 T 28-03-2018 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|Reactome: R-HSA-71182 CU254_RS25050 3ea6dc87afe14cb635ccf7c9089a88b6 399 Gene3D G3DSA:2.60.120.10 226 371 8.6E-34 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS25050 3ea6dc87afe14cb635ccf7c9089a88b6 399 SUPERFAMILY SSF51182 6 394 5.69E-94 T 28-03-2018 IPR011051 RmlC-like cupin domain CU254_RS25050 3ea6dc87afe14cb635ccf7c9089a88b6 399 Gene3D G3DSA:2.60.120.10 57 221 1.1E-16 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS04475 0edf7c6bce614eecb32ed6f7a03c0c83 528 SUPERFAMILY SSF75304 41 520 2.09E-111 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS04475 0edf7c6bce614eecb32ed6f7a03c0c83 528 Pfam PF01425 Amidase 64 504 2.7E-105 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS04475 0edf7c6bce614eecb32ed6f7a03c0c83 528 Gene3D G3DSA:3.90.1300.10 36 527 2.8E-138 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS04805 1a7af9c0012832a6bc50bf6894ff1214 467 TIGRFAM TIGR03624 TIGR03624: putative hydrolase 57 413 6.4E-117 T 28-03-2018 IPR018766 Zinicin-like metallopeptidase type 2 CU254_RS04805 1a7af9c0012832a6bc50bf6894ff1214 467 Pfam PF10103 Zincin-like metallopeptidase 57 409 3.6E-116 T 28-03-2018 IPR018766 Zinicin-like metallopeptidase type 2 CU254_RS04805 1a7af9c0012832a6bc50bf6894ff1214 467 SUPERFAMILY SSF55486 56 413 2.12E-111 T 28-03-2018 CU254_RS18840 67f6f02d3ab70182b0b822663383924e 330 Gene3D G3DSA:1.10.260.40 3 59 1.5E-22 T 28-03-2018 CU254_RS18840 67f6f02d3ab70182b0b822663383924e 330 Pfam PF00356 Bacterial regulatory proteins, lacI family 6 49 1.0E-16 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CU254_RS18840 67f6f02d3ab70182b0b822663383924e 330 SMART SM00354 2 72 3.2E-26 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CU254_RS18840 67f6f02d3ab70182b0b822663383924e 330 Gene3D G3DSA:3.40.50.2300 166 329 1.3E-47 T 28-03-2018 CU254_RS18840 67f6f02d3ab70182b0b822663383924e 330 Gene3D G3DSA:3.40.50.2300 60 165 2.3E-22 T 28-03-2018 CU254_RS18840 67f6f02d3ab70182b0b822663383924e 330 Pfam PF13377 Periplasmic binding protein-like domain 166 326 3.1E-37 T 28-03-2018 CU254_RS18840 67f6f02d3ab70182b0b822663383924e 330 SUPERFAMILY SSF53822 63 328 2.16E-68 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CU254_RS18840 67f6f02d3ab70182b0b822663383924e 330 SUPERFAMILY SSF47413 3 60 4.29E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS15465 7d4e61db2b65903a6470442bf96f9bd0 313 TIGRFAM TIGR02772 Ku_bact: Ku protein 1 256 1.7E-85 T 28-03-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type CU254_RS15465 7d4e61db2b65903a6470442bf96f9bd0 313 Pfam PF02735 Ku70/Ku80 beta-barrel domain 11 191 1.1E-34 T 28-03-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 CU254_RS15465 7d4e61db2b65903a6470442bf96f9bd0 313 Hamap MF_01875 Non-homologous end joining protein Ku [ku]. 1 254 32.687 T 28-03-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type CU254_RS15465 7d4e61db2b65903a6470442bf96f9bd0 313 PIRSF PIRSF006493 266 312 120.0 T 28-03-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type CU254_RS15465 7d4e61db2b65903a6470442bf96f9bd0 313 PIRSF PIRSF006493 1 300 2.1E-94 T 28-03-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type CU254_RS15465 7d4e61db2b65903a6470442bf96f9bd0 313 Gene3D G3DSA:2.40.290.10 1 184 1.8E-29 T 28-03-2018 IPR016194 SPOC-like, C-terminal domain CU254_RS15465 7d4e61db2b65903a6470442bf96f9bd0 313 SUPERFAMILY SSF100939 1 254 1.37E-47 T 28-03-2018 IPR016194 SPOC-like, C-terminal domain CU254_RS15465 7d4e61db2b65903a6470442bf96f9bd0 313 SMART SM00559 52 181 1.2E-31 T 28-03-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 CU254_RS15465 7d4e61db2b65903a6470442bf96f9bd0 313 Gene3D G3DSA:1.10.720.10 276 313 1.4E-8 T 28-03-2018 CU254_RS02310 3ec9ffda0d3e8af48675e777e900276e 214 Pfam PF12079 Protein of unknown function (DUF3558) 33 208 5.0E-27 T 28-03-2018 IPR024520 Protein of unknown function DUF3558 CU254_RS14605 ac18087173493f1094b7ce134d536260 927 Pfam PF02754 Cysteine-rich domain 710 783 0.0041 T 28-03-2018 IPR004017 Cysteine-rich domain CU254_RS14605 ac18087173493f1094b7ce134d536260 927 SUPERFAMILY SSF56176 6 247 4.01E-53 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CU254_RS14605 ac18087173493f1094b7ce134d536260 927 SUPERFAMILY SSF55103 253 491 1.49E-52 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CU254_RS14605 ac18087173493f1094b7ce134d536260 927 Pfam PF01565 FAD binding domain 40 177 5.4E-41 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CU254_RS14605 ac18087173493f1094b7ce134d536260 927 Pfam PF02913 FAD linked oxidases, C-terminal domain 253 487 2.0E-47 T 28-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CU254_RS14605 ac18087173493f1094b7ce134d536260 927 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 591 602 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CU254_RS14605 ac18087173493f1094b7ce134d536260 927 Pfam PF13183 4Fe-4S dicluster domain 526 605 1.8E-8 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CU254_RS14605 ac18087173493f1094b7ce134d536260 927 Gene3D G3DSA:3.30.43.10 1 90 1.4E-20 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CU254_RS14605 ac18087173493f1094b7ce134d536260 927 Gene3D G3DSA:3.30.465.10 91 266 3.5E-41 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CU254_RS14605 ac18087173493f1094b7ce134d536260 927 SUPERFAMILY SSF46548 527 610 3.19E-9 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CU254_RS14605 ac18087173493f1094b7ce134d536260 927 Gene3D G3DSA:1.10.45.10 449 488 3.7E-9 T 28-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CU254_RS14605 ac18087173493f1094b7ce134d536260 927 Gene3D G3DSA:1.10.1060.10 516 624 4.5E-14 T 28-03-2018 CU254_RS06555 5c49c26059f04f32c3192d909453881f 114 SMART SM00418 9 83 4.4E-19 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS06555 5c49c26059f04f32c3192d909453881f 114 Gene3D G3DSA:1.10.10.10 1 110 3.0E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS06555 5c49c26059f04f32c3192d909453881f 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 58 73 9.7E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS06555 5c49c26059f04f32c3192d909453881f 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 43 58 9.7E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS06555 5c49c26059f04f32c3192d909453881f 114 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 11 26 9.7E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS06555 5c49c26059f04f32c3192d909453881f 114 Pfam PF12840 Helix-turn-helix domain 8 67 6.3E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS06555 5c49c26059f04f32c3192d909453881f 114 SUPERFAMILY SSF46785 6 100 6.81E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS35515 01271ced9991a372e001df43e06b9682 361 Pfam PF01266 FAD dependent oxidoreductase 8 337 1.9E-61 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CU254_RS35515 01271ced9991a372e001df43e06b9682 361 SUPERFAMILY SSF51905 301 356 8.55E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS35515 01271ced9991a372e001df43e06b9682 361 SUPERFAMILY SSF51905 7 209 8.55E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS35515 01271ced9991a372e001df43e06b9682 361 SUPERFAMILY SSF54373 207 299 1.96E-16 T 28-03-2018 CU254_RS35515 01271ced9991a372e001df43e06b9682 361 Gene3D G3DSA:3.50.50.60 2 166 4.4E-14 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS35515 01271ced9991a372e001df43e06b9682 361 TIGRFAM TIGR02352 thiamin_ThiO: glycine oxidase ThiO 8 341 2.6E-94 T 28-03-2018 IPR012727 Glycine oxidase ThiO GO:0016491|GO:0050660 CU254_RS35515 01271ced9991a372e001df43e06b9682 361 Gene3D G3DSA:3.30.9.10 167 300 3.8E-26 T 28-03-2018 CU254_RS00110 d94964a24bbeaf3047ccf301088f79f1 148 Pfam PF08592 Domain of unknown function (DUF1772) 18 146 4.1E-16 T 28-03-2018 IPR013901 Anthrone oxygenase CU254_RS42115 d5b2aed81078f0b86b1e5696e3af9900 554 Pfam PF04055 Radical SAM superfamily 214 382 3.0E-13 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CU254_RS42115 d5b2aed81078f0b86b1e5696e3af9900 554 SMART SM00729 206 436 2.1E-7 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CU254_RS42115 d5b2aed81078f0b86b1e5696e3af9900 554 Gene3D G3DSA:3.40.50.280 13 139 1.3E-11 T 28-03-2018 CU254_RS42115 d5b2aed81078f0b86b1e5696e3af9900 554 Gene3D G3DSA:3.20.20.70 140 452 1.7E-23 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS42115 d5b2aed81078f0b86b1e5696e3af9900 554 SUPERFAMILY SSF102114 176 395 1.22E-22 T 28-03-2018 CU254_RS42115 d5b2aed81078f0b86b1e5696e3af9900 554 Pfam PF02310 B12 binding domain 17 138 4.4E-10 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CU254_RS42115 d5b2aed81078f0b86b1e5696e3af9900 554 TIGRFAM TIGR04428 B12_rSAM_trp_MT: tryptophan 2-C-methyltransferase 5 546 1.0E-272 T 28-03-2018 IPR030969 Tryptophan 2-C-methyltransferase KEGG: 00270+2.1.1.10|MetaCyc: PWY-5441|MetaCyc: PWY-702 CU254_RS18670 2a587f28e4b5a761a0bcd3905329efd2 303 SUPERFAMILY SSF54593 1 271 2.5E-32 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS18670 2a587f28e4b5a761a0bcd3905329efd2 303 Gene3D G3DSA:3.10.180.10 134 289 2.4E-22 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS18670 2a587f28e4b5a761a0bcd3905329efd2 303 ProSitePatterns PS00082 Extradiol ring-cleavage dioxygenases signature. 241 262 - T 28-03-2018 IPR000486 Extradiol ring-cleavage dioxygenase, class I /II GO:0003824|GO:0006725|GO:0008198|GO:0055114 CU254_RS18670 2a587f28e4b5a761a0bcd3905329efd2 303 Gene3D G3DSA:3.10.180.10 1 130 7.1E-16 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS18670 2a587f28e4b5a761a0bcd3905329efd2 303 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 158 263 1.4E-19 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CU254_RS37610 23fa99c2a59e6eb98e4e08a56533023a 292 Pfam PF13560 Helix-turn-helix domain 22 81 4.6E-14 T 28-03-2018 CU254_RS37610 23fa99c2a59e6eb98e4e08a56533023a 292 SUPERFAMILY SSF47413 17 78 8.73E-7 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS37610 23fa99c2a59e6eb98e4e08a56533023a 292 Gene3D G3DSA:1.10.260.40 19 103 2.1E-11 T 28-03-2018 CU254_RS37610 23fa99c2a59e6eb98e4e08a56533023a 292 SMART SM00530 25 80 6.3E-5 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS13150 6ee3a7e2a009fbe616698f085d3fefae 378 Pfam PF06245 Protein of unknown function (DUF1015) 95 375 3.4E-31 T 28-03-2018 IPR008323 Uncharacterised conserved protein UCP033563 CU254_RS07735 95c216850bd767eb0ad518115872095b 98 ProSitePatterns PS00151 Acylphosphatase signature 2. 41 57 - T 28-03-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CU254_RS07735 95c216850bd767eb0ad518115872095b 98 Gene3D G3DSA:3.30.70.100 2 96 5.2E-28 T 28-03-2018 CU254_RS07735 95c216850bd767eb0ad518115872095b 98 SUPERFAMILY SSF54975 10 96 9.38E-26 T 28-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CU254_RS07735 95c216850bd767eb0ad518115872095b 98 Pfam PF00708 Acylphosphatase 15 95 1.2E-23 T 28-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CU254_RS07735 95c216850bd767eb0ad518115872095b 98 ProSitePatterns PS00150 Acylphosphatase signature 1. 17 27 - T 28-03-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CU254_RS20720 8732e15846feb12c2051f15e2deb1cf0 393 Gene3D G3DSA:3.60.15.10 6 247 1.2E-21 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS20720 8732e15846feb12c2051f15e2deb1cf0 393 Pfam PF00753 Metallo-beta-lactamase superfamily 28 221 3.5E-11 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS20720 8732e15846feb12c2051f15e2deb1cf0 393 SMART SM00849 29 223 4.3E-8 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS20720 8732e15846feb12c2051f15e2deb1cf0 393 SUPERFAMILY SSF56281 9 392 3.22E-68 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS20720 8732e15846feb12c2051f15e2deb1cf0 393 Pfam PF14863 Alkyl sulfatase dimerisation 259 392 5.4E-26 T 28-03-2018 IPR029228 Alkyl sulfatase dimerisation domain GO:0046983 CU254_RS35670 b170d8e3432eeb118333fac6cfce06ec 164 SUPERFAMILY SSF46785 5 120 2.37E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS35670 b170d8e3432eeb118333fac6cfce06ec 164 Gene3D G3DSA:1.10.10.10 3 163 5.4E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS35670 b170d8e3432eeb118333fac6cfce06ec 164 Pfam PF01638 HxlR-like helix-turn-helix 17 104 1.2E-14 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type CU254_RS34050 b59ace6b232e82805d61a939fffb003d 261 Gene3D G3DSA:3.40.50.1820 12 259 1.9E-37 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS34050 b59ace6b232e82805d61a939fffb003d 261 Pfam PF12697 Alpha/beta hydrolase family 33 255 1.4E-16 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS34050 b59ace6b232e82805d61a939fffb003d 261 SUPERFAMILY SSF53474 12 258 5.99E-40 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS21245 2886b49c005bdcac34149c894be95753 190 Pfam PF02575 YbaB/EbfC DNA-binding family 33 109 1.0E-10 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CU254_RS21245 2886b49c005bdcac34149c894be95753 190 Gene3D G3DSA:3.30.1310.10 18 112 1.1E-18 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CU254_RS21245 2886b49c005bdcac34149c894be95753 190 SUPERFAMILY SSF82607 33 111 7.72E-8 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CU254_RS42010 188668cd6eab871699ae954352efc54b 498 Pfam PF00589 Phage integrase family 225 380 1.3E-12 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CU254_RS42010 188668cd6eab871699ae954352efc54b 498 Gene3D G3DSA:1.10.443.10 192 389 2.0E-25 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CU254_RS42010 188668cd6eab871699ae954352efc54b 498 Gene3D G3DSA:1.10.150.130 84 191 8.9E-16 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CU254_RS42010 188668cd6eab871699ae954352efc54b 498 SUPERFAMILY SSF56349 91 381 6.47E-30 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CU254_RS42010 188668cd6eab871699ae954352efc54b 498 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 95 165 6.5E-7 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CU254_RS26870 aded5dce94f13c2e884dde462bc948d1 160 Pfam PF12802 MarR family 53 105 7.8E-8 T 28-03-2018 CU254_RS26870 aded5dce94f13c2e884dde462bc948d1 160 SMART SM00347 42 141 0.0038 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS26870 aded5dce94f13c2e884dde462bc948d1 160 SUPERFAMILY SSF46785 20 155 6.07E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS26870 aded5dce94f13c2e884dde462bc948d1 160 Gene3D G3DSA:1.10.10.10 19 154 1.5E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS28570 bba88a0785510c3a8826703edaf191aa 284 PIRSF PIRSF006648 3 266 1.1E-17 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CU254_RS28570 bba88a0785510c3a8826703edaf191aa 284 Pfam PF01061 ABC-2 type transporter 13 223 3.0E-20 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CU254_RS16510 e9ebc5ef4e2c80e2e28bce804abc3c9c 320 TIGRFAM TIGR03557 F420_G6P_family: F420-dependent oxidoreductase, G6PDH family 3 320 2.4E-133 T 28-03-2018 IPR019945 F420-dependent glucose-6-phosphate dehydrogenase-related CU254_RS16510 e9ebc5ef4e2c80e2e28bce804abc3c9c 320 Gene3D G3DSA:3.20.20.30 5 320 2.2E-57 T 28-03-2018 CU254_RS16510 e9ebc5ef4e2c80e2e28bce804abc3c9c 320 SUPERFAMILY SSF51679 1 320 1.77E-58 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS16510 e9ebc5ef4e2c80e2e28bce804abc3c9c 320 Pfam PF00296 Luciferase-like monooxygenase 1 291 2.2E-45 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS20480 3ec22af80c5f9eaae4e36afe16bde8c3 445 Gene3D G3DSA:3.50.50.60 208 437 5.1E-15 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS20480 3ec22af80c5f9eaae4e36afe16bde8c3 445 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 13 353 5.2E-111 T 28-03-2018 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase CU254_RS20480 3ec22af80c5f9eaae4e36afe16bde8c3 445 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 164 182 7.6E-7 T 28-03-2018 CU254_RS20480 3ec22af80c5f9eaae4e36afe16bde8c3 445 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 16 35 7.6E-7 T 28-03-2018 CU254_RS20480 3ec22af80c5f9eaae4e36afe16bde8c3 445 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 207 225 7.6E-7 T 28-03-2018 CU254_RS20480 3ec22af80c5f9eaae4e36afe16bde8c3 445 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 207 232 2.9E-5 T 28-03-2018 CU254_RS20480 3ec22af80c5f9eaae4e36afe16bde8c3 445 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 15 37 2.9E-5 T 28-03-2018 CU254_RS20480 3ec22af80c5f9eaae4e36afe16bde8c3 445 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 167 176 2.9E-5 T 28-03-2018 CU254_RS20480 3ec22af80c5f9eaae4e36afe16bde8c3 445 Gene3D G3DSA:3.50.50.60 14 207 5.4E-17 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS20480 3ec22af80c5f9eaae4e36afe16bde8c3 445 SUPERFAMILY SSF51905 204 233 2.72E-8 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS20480 3ec22af80c5f9eaae4e36afe16bde8c3 445 SUPERFAMILY SSF51905 277 430 2.72E-8 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS20480 3ec22af80c5f9eaae4e36afe16bde8c3 445 SUPERFAMILY SSF51905 13 240 2.85E-21 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS34740 9a09bb94c398faeaa770c8808a5143d4 133 Pfam PF03061 Thioesterase superfamily 46 124 1.4E-17 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CU254_RS34740 9a09bb94c398faeaa770c8808a5143d4 133 SUPERFAMILY SSF54637 7 131 3.3E-31 T 28-03-2018 IPR029069 HotDog domain CU254_RS34740 9a09bb94c398faeaa770c8808a5143d4 133 Gene3D G3DSA:3.10.129.10 3 133 1.3E-30 T 28-03-2018 CU254_RS34740 9a09bb94c398faeaa770c8808a5143d4 133 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 16 131 4.4E-23 T 28-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 CU254_RS37920 b37d8734aa2b270d14e3b5a6c808d3c6 545 TIGRFAM TIGR00831 a_cpa1: Na+/H+ antiporter 7 534 7.0E-89 T 28-03-2018 IPR004705 Cation/H+ exchanger, CPA1 family, bacteria GO:0006812|GO:0015299|GO:0016021 CU254_RS37920 b37d8734aa2b270d14e3b5a6c808d3c6 545 Pfam PF00999 Sodium/hydrogen exchanger family 8 406 2.1E-52 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CU254_RS35530 fb0cb48fe5cb058c1eee0d1c9a1af125 314 Gene3D G3DSA:3.40.50.1100 130 314 1.8E-45 T 28-03-2018 CU254_RS35530 fb0cb48fe5cb058c1eee0d1c9a1af125 314 Gene3D G3DSA:3.40.50.1100 26 129 8.9E-27 T 28-03-2018 CU254_RS35530 fb0cb48fe5cb058c1eee0d1c9a1af125 314 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 23 301 3.1E-77 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CU254_RS35530 fb0cb48fe5cb058c1eee0d1c9a1af125 314 SUPERFAMILY SSF53686 5 309 1.13E-86 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CU254_RS10485 33798139296c3a4947a8a035bdfad850 392 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 292 308 2.8E-22 T 28-03-2018 CU254_RS10485 33798139296c3a4947a8a035bdfad850 392 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 144 159 2.8E-22 T 28-03-2018 CU254_RS10485 33798139296c3a4947a8a035bdfad850 392 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 277 292 2.8E-22 T 28-03-2018 CU254_RS10485 33798139296c3a4947a8a035bdfad850 392 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 2.8E-22 T 28-03-2018 CU254_RS10485 33798139296c3a4947a8a035bdfad850 392 Pfam PF01494 FAD binding domain 2 164 1.3E-17 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CU254_RS10485 33798139296c3a4947a8a035bdfad850 392 Pfam PF01494 FAD binding domain 272 339 1.0E-8 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CU254_RS10485 33798139296c3a4947a8a035bdfad850 392 SUPERFAMILY SSF51905 1 165 1.21E-60 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS10485 33798139296c3a4947a8a035bdfad850 392 SUPERFAMILY SSF51905 264 362 1.21E-60 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS10485 33798139296c3a4947a8a035bdfad850 392 Gene3D G3DSA:3.50.50.60 1 345 4.1E-50 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS32570 da0df51a4cbd7070d961f1de37f0445b 75 Gene3D G3DSA:2.20.25.10 12 61 2.0E-17 T 28-03-2018 CU254_RS32570 da0df51a4cbd7070d961f1de37f0445b 75 Pfam PF03966 Trm112p-like protein 7 50 3.4E-8 T 28-03-2018 IPR005651 Uncharacterised protein family UPF0434/Trm112 CU254_RS32570 da0df51a4cbd7070d961f1de37f0445b 75 SUPERFAMILY SSF158997 6 61 1.96E-14 T 28-03-2018 CU254_RS41740 e3c6fefd8523f3dfe15a7d7f689149ea 538 Gene3D G3DSA:1.10.630.10 143 447 0.0026 T 28-03-2018 CU254_RS41740 e3c6fefd8523f3dfe15a7d7f689149ea 538 Pfam PF03432 Relaxase/Mobilisation nuclease domain 139 276 3.6E-7 T 28-03-2018 IPR005094 Endonuclease relaxase, MobA/VirD2 CU254_RS14545 be5c4ab94db6ae8d722df772444b1464 210 Pfam PF06197 Protein of unknown function (DUF998) 21 202 9.1E-25 T 28-03-2018 IPR009339 Protein of unknown function DUF998 CU254_RS29595 4c7d7349ffd5b768fc31c96479c68e44 258 Pfam PF17409 MoaF C-terminal domain 140 247 1.7E-36 T 28-03-2018 IPR035348 MoaF, C-terminal domain CU254_RS29595 4c7d7349ffd5b768fc31c96479c68e44 258 Gene3D G3DSA:2.40.128.20 142 240 1.4E-15 T 28-03-2018 IPR012674 Calycin CU254_RS29595 4c7d7349ffd5b768fc31c96479c68e44 258 Gene3D G3DSA:2.40.128.20 30 111 2.4E-11 T 28-03-2018 IPR012674 Calycin CU254_RS29595 4c7d7349ffd5b768fc31c96479c68e44 258 Pfam PF10703 MoaF N-terminal domain 11 109 4.8E-18 T 28-03-2018 IPR024724 Molybdenum cofactor biosynthesis protein F, N-terminal CU254_RS39470 44383665a26c3c2f839c9788c2515856 214 PRINTS PR00097 Anthranilate synthase component II signature 165 178 1.8E-34 T 28-03-2018 CU254_RS39470 44383665a26c3c2f839c9788c2515856 214 PRINTS PR00097 Anthranilate synthase component II signature 46 55 1.8E-34 T 28-03-2018 CU254_RS39470 44383665a26c3c2f839c9788c2515856 214 PRINTS PR00097 Anthranilate synthase component II signature 3 17 1.8E-34 T 28-03-2018 CU254_RS39470 44383665a26c3c2f839c9788c2515856 214 PRINTS PR00097 Anthranilate synthase component II signature 99 107 1.8E-34 T 28-03-2018 CU254_RS39470 44383665a26c3c2f839c9788c2515856 214 PRINTS PR00097 Anthranilate synthase component II signature 74 85 1.8E-34 T 28-03-2018 CU254_RS39470 44383665a26c3c2f839c9788c2515856 214 PRINTS PR00097 Anthranilate synthase component II signature 119 131 1.8E-34 T 28-03-2018 CU254_RS39470 44383665a26c3c2f839c9788c2515856 214 SUPERFAMILY SSF52317 1 189 2.37E-54 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS39470 44383665a26c3c2f839c9788c2515856 214 PRINTS PR00096 Glutamine amidotransferase superfamily signature 46 55 9.0E-14 T 28-03-2018 CU254_RS39470 44383665a26c3c2f839c9788c2515856 214 PRINTS PR00096 Glutamine amidotransferase superfamily signature 165 178 9.0E-14 T 28-03-2018 CU254_RS39470 44383665a26c3c2f839c9788c2515856 214 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 9.0E-14 T 28-03-2018 CU254_RS39470 44383665a26c3c2f839c9788c2515856 214 Gene3D G3DSA:3.40.50.880 1 192 5.5E-58 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS39470 44383665a26c3c2f839c9788c2515856 214 Pfam PF00117 Glutamine amidotransferase class-I 5 185 1.2E-52 T 28-03-2018 IPR017926 Glutamine amidotransferase CU254_RS39470 44383665a26c3c2f839c9788c2515856 214 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 43 57 1.3E-7 T 28-03-2018 CU254_RS39470 44383665a26c3c2f839c9788c2515856 214 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 1.3E-7 T 28-03-2018 CU254_RS39470 44383665a26c3c2f839c9788c2515856 214 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 3 186 5.7E-63 T 28-03-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CU254_RS06175 8fa7e3c48a982340d099e5e0a467500d 575 Gene3D G3DSA:1.20.140.10 243 397 2.2E-18 T 28-03-2018 CU254_RS06175 8fa7e3c48a982340d099e5e0a467500d 575 Gene3D G3DSA:1.10.540.10 12 136 2.3E-8 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS06175 8fa7e3c48a982340d099e5e0a467500d 575 Gene3D G3DSA:2.40.110.10 138 242 7.3E-14 T 28-03-2018 CU254_RS06175 8fa7e3c48a982340d099e5e0a467500d 575 SUPERFAMILY SSF56645 19 241 8.12E-31 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS06175 8fa7e3c48a982340d099e5e0a467500d 575 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 247 395 1.6E-15 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS06175 8fa7e3c48a982340d099e5e0a467500d 575 SUPERFAMILY SSF47203 246 397 9.02E-22 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS10015 8a2e33706599efdfa6a004de1fb7b196 598 Gene3D G3DSA:2.30.38.10 387 459 1.6E-19 T 28-03-2018 CU254_RS10015 8a2e33706599efdfa6a004de1fb7b196 598 Gene3D G3DSA:3.40.50.980 13 190 1.1E-38 T 28-03-2018 CU254_RS10015 8a2e33706599efdfa6a004de1fb7b196 598 Gene3D G3DSA:3.30.300.30 461 598 7.5E-16 T 28-03-2018 CU254_RS10015 8a2e33706599efdfa6a004de1fb7b196 598 SUPERFAMILY SSF56801 17 289 1.44E-113 T 28-03-2018 CU254_RS10015 8a2e33706599efdfa6a004de1fb7b196 598 SUPERFAMILY SSF56801 337 596 1.44E-113 T 28-03-2018 CU254_RS10015 8a2e33706599efdfa6a004de1fb7b196 598 Gene3D G3DSA:3.40.50.980 191 386 2.4E-39 T 28-03-2018 CU254_RS10015 8a2e33706599efdfa6a004de1fb7b196 598 ProSitePatterns PS00455 Putative AMP-binding domain signature. 185 196 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS10015 8a2e33706599efdfa6a004de1fb7b196 598 Pfam PF00501 AMP-binding enzyme 23 466 1.9E-95 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS13940 39339830b50c09b02e4554c73256b6cc 398 Gene3D G3DSA:1.10.10.60 314 366 1.8E-4 T 28-03-2018 CU254_RS13940 39339830b50c09b02e4554c73256b6cc 398 Pfam PF13556 PucR C-terminal helix-turn-helix domain 332 387 9.0E-17 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CU254_RS13240 119dd2dd61436ec543a1c67a8d847644 130 Pfam PF12680 SnoaL-like domain 28 118 8.6E-10 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CU254_RS13240 119dd2dd61436ec543a1c67a8d847644 130 SUPERFAMILY SSF54427 8 121 1.73E-14 T 28-03-2018 IPR032710 NTF2-like domain CU254_RS13240 119dd2dd61436ec543a1c67a8d847644 130 Gene3D G3DSA:3.10.450.50 4 129 4.1E-16 T 28-03-2018 CU254_RS14485 f9b50b65c8694744068785f277263da2 396 Pfam PF02515 CoA-transferase family III 5 372 1.1E-119 T 28-03-2018 IPR003673 CoA-transferase family III GO:0003824 CU254_RS14485 f9b50b65c8694744068785f277263da2 396 SUPERFAMILY SSF89796 2 396 5.62E-129 T 28-03-2018 IPR023606 CoA-transferase family III domain CU254_RS14485 f9b50b65c8694744068785f277263da2 396 Gene3D G3DSA:3.40.50.10540 1 396 1.5E-139 T 28-03-2018 IPR023606 CoA-transferase family III domain CU254_RS03060 d1919f338bafd044dbc23db97ffdbf3b 302 SUPERFAMILY SSF46785 4 86 1.14E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS03060 d1919f338bafd044dbc23db97ffdbf3b 302 Pfam PF03466 LysR substrate binding domain 90 278 1.1E-39 T 28-03-2018 IPR005119 LysR, substrate-binding CU254_RS03060 d1919f338bafd044dbc23db97ffdbf3b 302 Gene3D G3DSA:3.40.190.10 178 266 4.5E-23 T 28-03-2018 CU254_RS03060 d1919f338bafd044dbc23db97ffdbf3b 302 SUPERFAMILY SSF53850 91 297 5.43E-41 T 28-03-2018 CU254_RS03060 d1919f338bafd044dbc23db97ffdbf3b 302 Gene3D G3DSA:3.40.190.10 89 177 8.7E-21 T 28-03-2018 CU254_RS03060 d1919f338bafd044dbc23db97ffdbf3b 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 7.3E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS03060 d1919f338bafd044dbc23db97ffdbf3b 302 Gene3D G3DSA:1.10.10.10 2 84 5.8E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS36405 7d40d66eaee5801b525529b74bcf7f01 195 Gene3D G3DSA:1.10.357.10 8 191 1.0E-28 T 28-03-2018 CU254_RS36405 7d40d66eaee5801b525529b74bcf7f01 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 67 3.1E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS36405 7d40d66eaee5801b525529b74bcf7f01 195 SUPERFAMILY SSF48498 89 178 3.05E-8 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS36405 7d40d66eaee5801b525529b74bcf7f01 195 SUPERFAMILY SSF46689 14 94 5.64E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS32190 80422253d3a479b4aa970745069dcb97 313 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 141 162 - T 28-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 CU254_RS32190 80422253d3a479b4aa970745069dcb97 313 Gene3D G3DSA:3.90.180.10 1 139 7.2E-30 T 28-03-2018 CU254_RS32190 80422253d3a479b4aa970745069dcb97 313 SUPERFAMILY SSF51735 114 257 7.89E-33 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS32190 80422253d3a479b4aa970745069dcb97 313 SMART SM00829 10 311 1.4E-11 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CU254_RS32190 80422253d3a479b4aa970745069dcb97 313 SUPERFAMILY SSF50129 1 150 2.13E-26 T 28-03-2018 IPR011032 GroES-like CU254_RS32190 80422253d3a479b4aa970745069dcb97 313 Gene3D G3DSA:3.40.50.720 140 294 8.4E-24 T 28-03-2018 CU254_RS32190 80422253d3a479b4aa970745069dcb97 313 Pfam PF00107 Zinc-binding dehydrogenase 152 265 6.1E-22 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CU254_RS14985 489fe2a563699a4eac7584fc8663fc8d 540 SUPERFAMILY SSF51556 61 120 3.23E-28 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS14985 489fe2a563699a4eac7584fc8663fc8d 540 SUPERFAMILY SSF51556 200 499 3.23E-28 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS14985 489fe2a563699a4eac7584fc8663fc8d 540 Gene3D G3DSA:2.30.40.10 1 119 7.0E-20 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS14985 489fe2a563699a4eac7584fc8663fc8d 540 Pfam PF07969 Amidohydrolase family 50 538 4.3E-85 T 28-03-2018 IPR013108 Amidohydrolase 3 CU254_RS14985 489fe2a563699a4eac7584fc8663fc8d 540 Gene3D G3DSA:3.20.20.140 184 496 2.7E-44 T 28-03-2018 CU254_RS14985 489fe2a563699a4eac7584fc8663fc8d 540 SUPERFAMILY SSF51338 498 539 4.32E-18 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS14985 489fe2a563699a4eac7584fc8663fc8d 540 SUPERFAMILY SSF51338 4 62 4.32E-18 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS20970 2d92fcf03fd399b1ad36afacc8c37d21 368 Pfam PF01569 PAP2 superfamily 70 178 2.8E-18 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CU254_RS20970 2d92fcf03fd399b1ad36afacc8c37d21 368 Gene3D G3DSA:1.20.144.10 2 183 2.5E-26 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CU254_RS20970 2d92fcf03fd399b1ad36afacc8c37d21 368 SUPERFAMILY SSF48317 23 177 1.01E-28 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CU254_RS20970 2d92fcf03fd399b1ad36afacc8c37d21 368 SMART SM00014 64 175 2.6E-14 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CU254_RS41005 a21a2e750986fc185af2573d4f2a16d6 237 Gene3D G3DSA:3.40.50.620 9 205 7.9E-12 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS41005 a21a2e750986fc185af2573d4f2a16d6 237 SUPERFAMILY SSF52402 9 197 2.02E-21 T 28-03-2018 CU254_RS41005 a21a2e750986fc185af2573d4f2a16d6 237 Pfam PF06508 Queuosine biosynthesis protein QueC 69 186 6.8E-11 T 28-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 CU254_RS40660 2197c65e71e5a39b59f2c6b99fbb79df 743 Pfam PF04738 Lantibiotic dehydratase, C terminus 140 214 3.7E-7 T 28-03-2018 IPR006827 Lantibiotic dehydratase, C-terminal CU254_RS01080 780d7feb4d4a6657fc77aada73de2498 71 Gene3D G3DSA:1.10.1660.20 16 60 1.2E-11 T 28-03-2018 CU254_RS01080 780d7feb4d4a6657fc77aada73de2498 71 SUPERFAMILY SSF46955 17 64 2.38E-5 T 28-03-2018 IPR009061 Putative DNA-binding domain CU254_RS01080 780d7feb4d4a6657fc77aada73de2498 71 Pfam PF12728 Helix-turn-helix domain 17 65 1.2E-15 T 28-03-2018 CU254_RS01080 780d7feb4d4a6657fc77aada73de2498 71 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 17 63 1.5E-20 T 28-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 CU254_RS01480 b02603ea7d27de569a9e3f7532fa3dea 222 Pfam PF01522 Polysaccharide deacetylase 44 165 7.8E-22 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CU254_RS01480 b02603ea7d27de569a9e3f7532fa3dea 222 SUPERFAMILY SSF88713 28 181 4.45E-25 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CU254_RS01480 b02603ea7d27de569a9e3f7532fa3dea 222 Gene3D G3DSA:3.20.20.370 26 201 2.9E-26 T 28-03-2018 CU254_RS18220 c36560e96a53e94473922fc56ef52fb8 172 Gene3D G3DSA:3.90.79.10 2 171 1.6E-32 T 28-03-2018 CU254_RS18220 c36560e96a53e94473922fc56ef52fb8 172 SUPERFAMILY SSF55811 6 161 4.87E-31 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CU254_RS18220 c36560e96a53e94473922fc56ef52fb8 172 PIRSF PIRSF017340 1 171 7.2E-53 T 28-03-2018 IPR024195 NUDIX hydrolase, YfcD, predicted GO:0016817 CU254_RS18220 c36560e96a53e94473922fc56ef52fb8 172 ProSitePatterns PS00893 Nudix box signature. 70 91 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CU254_RS18220 c36560e96a53e94473922fc56ef52fb8 172 Pfam PF00293 NUDIX domain 34 150 2.0E-17 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CU254_RS38360 525516b7186acc976566bc31f22d6909 330 SUPERFAMILY SSF160240 230 308 6.67E-6 T 28-03-2018 CU254_RS38360 525516b7186acc976566bc31f22d6909 330 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 15 308 4.8E-45 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CU254_RS38360 525516b7186acc976566bc31f22d6909 330 SUPERFAMILY SSF161111 13 227 2.75E-35 T 28-03-2018 CU254_RS38360 525516b7186acc976566bc31f22d6909 330 Pfam PF01545 Cation efflux family 17 221 1.1E-33 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CU254_RS38360 525516b7186acc976566bc31f22d6909 330 Gene3D G3DSA:3.30.70.1350 225 317 9.8E-8 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CU254_RS38360 525516b7186acc976566bc31f22d6909 330 Gene3D G3DSA:1.20.1510.10 12 224 2.5E-28 T 28-03-2018 CU254_RS22755 3231adf20c03c72ae6af4f267493a16b 258 SUPERFAMILY SSF52096 9 255 1.81E-52 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS22755 3231adf20c03c72ae6af4f267493a16b 258 Gene3D G3DSA:3.90.226.10 9 219 1.4E-43 T 28-03-2018 CU254_RS22755 3231adf20c03c72ae6af4f267493a16b 258 Pfam PF00378 Enoyl-CoA hydratase/isomerase 15 254 1.1E-39 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CU254_RS22755 3231adf20c03c72ae6af4f267493a16b 258 Gene3D G3DSA:1.10.12.10 220 254 2.3E-4 T 28-03-2018 IPR014748 Crontonase, C-terminal CU254_RS21490 18019ccda6d84692cb78a8a90e21a41f 147 Gene3D G3DSA:2.60.120.10 2 146 9.7E-41 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS21490 18019ccda6d84692cb78a8a90e21a41f 147 SUPERFAMILY SSF51182 3 141 5.16E-37 T 28-03-2018 IPR011051 RmlC-like cupin domain CU254_RS21490 18019ccda6d84692cb78a8a90e21a41f 147 Pfam PF06172 Cupin superfamily (DUF985) 6 126 1.9E-29 T 28-03-2018 IPR009327 Cupin domain of unknown function DUF985 CU254_RS36315 b5fffdc34a63d0f748b9640d7723402c 119 SUPERFAMILY SSF55620 1 119 1.95E-35 T 28-03-2018 CU254_RS36315 b5fffdc34a63d0f748b9640d7723402c 119 SMART SM00905 5 117 2.3E-49 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CU254_RS36315 b5fffdc34a63d0f748b9640d7723402c 119 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 3 117 1.6E-37 T 28-03-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CU254_RS36315 b5fffdc34a63d0f748b9640d7723402c 119 Pfam PF02152 Dihydroneopterin aldolase 5 116 4.0E-32 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CU254_RS36315 b5fffdc34a63d0f748b9640d7723402c 119 TIGRFAM TIGR00526 folB_dom: FolB domain 2 119 3.5E-32 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CU254_RS36315 b5fffdc34a63d0f748b9640d7723402c 119 Gene3D G3DSA:3.30.1130.10 1 119 1.4E-35 T 28-03-2018 CU254_RS19340 b1acb842b2decfa12c6fde9504afaaef 211 SMART SM00382 25 201 4.7E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS19340 b1acb842b2decfa12c6fde9504afaaef 211 Gene3D G3DSA:3.40.50.300 1 210 1.9E-49 T 28-03-2018 CU254_RS19340 b1acb842b2decfa12c6fde9504afaaef 211 SUPERFAMILY SSF52540 2 206 3.2E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS19340 b1acb842b2decfa12c6fde9504afaaef 211 Pfam PF00005 ABC transporter 17 157 3.1E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS02280 88a551f94c7b3ebec7e6aba7cb7fb1b2 413 Pfam PF04228 Putative neutral zinc metallopeptidase 217 404 1.6E-20 T 28-03-2018 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative CU254_RS22195 a4394fcf2a9c17058f8bdbdc5ae4579a 274 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 170 1.0E-21 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CU254_RS22195 a4394fcf2a9c17058f8bdbdc5ae4579a 274 SUPERFAMILY SSF51735 1 232 1.05E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS22195 a4394fcf2a9c17058f8bdbdc5ae4579a 274 Gene3D G3DSA:3.40.50.720 1 236 4.2E-38 T 28-03-2018 CU254_RS16855 4e12d290088ff8153499029dadb36ecd 350 Pfam PF00356 Bacterial regulatory proteins, lacI family 20 65 1.9E-12 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CU254_RS16855 4e12d290088ff8153499029dadb36ecd 350 Pfam PF13377 Periplasmic binding protein-like domain 178 316 1.1E-24 T 28-03-2018 CU254_RS16855 4e12d290088ff8153499029dadb36ecd 350 SUPERFAMILY SSF53822 75 317 2.75E-48 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CU254_RS16855 4e12d290088ff8153499029dadb36ecd 350 Gene3D G3DSA:3.40.50.2300 184 315 2.3E-34 T 28-03-2018 CU254_RS16855 4e12d290088ff8153499029dadb36ecd 350 Gene3D G3DSA:3.40.50.2300 71 183 1.2E-20 T 28-03-2018 CU254_RS16855 4e12d290088ff8153499029dadb36ecd 350 SUPERFAMILY SSF47413 18 77 3.09E-12 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS16855 4e12d290088ff8153499029dadb36ecd 350 Gene3D G3DSA:1.10.260.40 19 70 3.4E-17 T 28-03-2018 CU254_RS16855 4e12d290088ff8153499029dadb36ecd 350 SMART SM00354 17 88 7.8E-24 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CU254_RS29685 9e5bf56b24b70b987867bcdfad28c541 713 Gene3D G3DSA:3.40.50.1820 420 628 8.1E-5 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS29685 9e5bf56b24b70b987867bcdfad28c541 713 Pfam PF05990 Alpha/beta hydrolase of unknown function (DUF900) 432 662 2.7E-7 T 28-03-2018 IPR010297 Protein of unknown function DUF900, hydrolase-like CU254_RS13085 11d552e747e4a9ad94ddb399f5eb0bea 296 Gene3D G3DSA:3.30.420.40 121 295 4.6E-38 T 28-03-2018 CU254_RS13085 11d552e747e4a9ad94ddb399f5eb0bea 296 SUPERFAMILY SSF53067 7 294 3.75E-49 T 28-03-2018 CU254_RS13085 11d552e747e4a9ad94ddb399f5eb0bea 296 Gene3D G3DSA:3.30.420.40 2 120 3.7E-28 T 28-03-2018 CU254_RS13085 11d552e747e4a9ad94ddb399f5eb0bea 296 Pfam PF00480 ROK family 8 294 5.8E-41 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CU254_RS37485 4a016e9681312b16520b4ef3631d8228 433 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 2 398 4.9E-73 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CU254_RS37485 4a016e9681312b16520b4ef3631d8228 433 SUPERFAMILY SSF103473 3 186 5.75E-67 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS37485 4a016e9681312b16520b4ef3631d8228 433 SUPERFAMILY SSF103473 228 424 5.75E-67 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS37485 4a016e9681312b16520b4ef3631d8228 433 Gene3D G3DSA:1.20.1250.20 1 189 7.0E-33 T 28-03-2018 CU254_RS37485 4a016e9681312b16520b4ef3631d8228 433 Pfam PF07690 Major Facilitator Superfamily 6 389 1.6E-51 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS37485 4a016e9681312b16520b4ef3631d8228 433 Gene3D G3DSA:1.20.1250.20 239 432 2.9E-22 T 28-03-2018 CU254_RS29805 38c9fae8e3c770638dd6596823d52fab 540 Gene3D G3DSA:3.40.50.300 2 274 8.4E-54 T 28-03-2018 CU254_RS29805 38c9fae8e3c770638dd6596823d52fab 540 SMART SM00382 30 215 6.1E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS29805 38c9fae8e3c770638dd6596823d52fab 540 SMART SM00382 363 535 1.4E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS29805 38c9fae8e3c770638dd6596823d52fab 540 Gene3D G3DSA:3.40.50.300 284 540 1.9E-39 T 28-03-2018 CU254_RS29805 38c9fae8e3c770638dd6596823d52fab 540 SUPERFAMILY SSF52540 6 220 1.63E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS29805 38c9fae8e3c770638dd6596823d52fab 540 Pfam PF00005 ABC transporter 357 485 2.3E-18 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS29805 38c9fae8e3c770638dd6596823d52fab 540 Pfam PF00005 ABC transporter 24 171 3.9E-20 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS29805 38c9fae8e3c770638dd6596823d52fab 540 SUPERFAMILY SSF52540 345 537 8.6E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS36005 0c41b1d3c3f555c88efad8331461010c 318 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 71 312 2.0E-58 T 28-03-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 CU254_RS36005 0c41b1d3c3f555c88efad8331461010c 318 SMART SM00967 72 148 9.4E-17 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CU254_RS36005 0c41b1d3c3f555c88efad8331461010c 318 Gene3D G3DSA:3.30.1330.30 42 144 3.5E-13 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CU254_RS36005 0c41b1d3c3f555c88efad8331461010c 318 SUPERFAMILY SSF75217 137 316 3.4E-42 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CU254_RS36005 0c41b1d3c3f555c88efad8331461010c 318 Pfam PF00588 SpoU rRNA Methylase family 165 305 1.2E-33 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CU254_RS36005 0c41b1d3c3f555c88efad8331461010c 318 SUPERFAMILY SSF55315 66 145 2.24E-14 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CU254_RS36005 0c41b1d3c3f555c88efad8331461010c 318 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 72 147 4.8E-15 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CU254_RS36005 0c41b1d3c3f555c88efad8331461010c 318 Gene3D G3DSA:3.40.1280.10 146 317 1.2E-44 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CU254_RS25700 2972b22fc36fdada64faafb174da18a9 150 Gene3D G3DSA:1.10.1660.10 10 65 1.3E-20 T 28-03-2018 CU254_RS25700 2972b22fc36fdada64faafb174da18a9 150 TIGRFAM TIGR01950 SoxR: redox-sensitive transcriptional activator SoxR 11 148 5.2E-61 T 28-03-2018 IPR010211 Redox-sensitive transcriptional activator SoxR GO:0003677|GO:0006355|GO:0006979|GO:0051537 CU254_RS25700 2972b22fc36fdada64faafb174da18a9 150 Pfam PF00376 MerR family regulatory protein 13 48 6.6E-13 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS25700 2972b22fc36fdada64faafb174da18a9 150 SMART SM00422 11 79 2.6E-23 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS25700 2972b22fc36fdada64faafb174da18a9 150 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 23 36 2.0E-11 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS25700 2972b22fc36fdada64faafb174da18a9 150 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 46 66 2.0E-11 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS25700 2972b22fc36fdada64faafb174da18a9 150 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 12 23 2.0E-11 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS25700 2972b22fc36fdada64faafb174da18a9 150 SUPERFAMILY SSF46955 12 133 4.76E-29 T 28-03-2018 IPR009061 Putative DNA-binding domain CU254_RS25700 2972b22fc36fdada64faafb174da18a9 150 Pfam PF09278 MerR, DNA binding 54 117 4.2E-17 T 28-03-2018 IPR015358 Transcription regulator MerR, DNA binding CU254_RS25700 2972b22fc36fdada64faafb174da18a9 150 Gene3D G3DSA:1.10.1660.10 66 135 1.2E-12 T 28-03-2018 CU254_RS25700 2972b22fc36fdada64faafb174da18a9 150 ProSitePatterns PS00552 MerR-type HTH domain signature. 14 36 - T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS35835 c22c889e3431e136a85a53687f6c3c19 405 Gene3D G3DSA:3.90.1300.10 5 405 2.6E-86 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS35835 c22c889e3431e136a85a53687f6c3c19 405 Pfam PF01425 Amidase 46 219 2.0E-48 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS35835 c22c889e3431e136a85a53687f6c3c19 405 Pfam PF01425 Amidase 227 393 3.4E-6 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS35835 c22c889e3431e136a85a53687f6c3c19 405 SUPERFAMILY SSF75304 5 403 2.75E-85 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS26940 ce9f9656d0dba1c77a66e1f568ff0957 148 SMART SM00347 31 131 1.1E-13 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS26940 ce9f9656d0dba1c77a66e1f568ff0957 148 SUPERFAMILY SSF46785 24 147 5.88E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS26940 ce9f9656d0dba1c77a66e1f568ff0957 148 Gene3D G3DSA:1.10.10.10 10 116 7.8E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS26940 ce9f9656d0dba1c77a66e1f568ff0957 148 Pfam PF01047 MarR family 38 96 2.1E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS26940 ce9f9656d0dba1c77a66e1f568ff0957 148 Gene3D G3DSA:1.10.287.100 117 147 8.9E-15 T 28-03-2018 CU254_RS24990 dc1c45a367a583313b35c1ad609a7aea 254 Pfam PF13714 Phosphoenolpyruvate phosphomutase 4 231 2.4E-61 T 28-03-2018 CU254_RS24990 dc1c45a367a583313b35c1ad609a7aea 254 Gene3D G3DSA:3.20.20.60 1 251 6.2E-45 T 28-03-2018 CU254_RS24990 dc1c45a367a583313b35c1ad609a7aea 254 SUPERFAMILY SSF51621 3 236 1.15E-44 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CU254_RS27785 d7bbaf4d4f2662a8cfcfd5c48bcb8371 396 Gene3D G3DSA:2.40.110.10 139 230 1.9E-37 T 28-03-2018 CU254_RS27785 d7bbaf4d4f2662a8cfcfd5c48bcb8371 396 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 140 230 1.0E-25 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CU254_RS27785 d7bbaf4d4f2662a8cfcfd5c48bcb8371 396 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 243 389 6.3E-30 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS27785 d7bbaf4d4f2662a8cfcfd5c48bcb8371 396 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 142 154 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CU254_RS27785 d7bbaf4d4f2662a8cfcfd5c48bcb8371 396 Gene3D G3DSA:1.10.540.10 2 138 6.6E-29 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS27785 d7bbaf4d4f2662a8cfcfd5c48bcb8371 396 SUPERFAMILY SSF47203 246 393 2.58E-38 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS27785 d7bbaf4d4f2662a8cfcfd5c48bcb8371 396 SUPERFAMILY SSF56645 12 241 1.05E-74 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS27785 d7bbaf4d4f2662a8cfcfd5c48bcb8371 396 Gene3D G3DSA:1.20.140.10 231 395 1.6E-34 T 28-03-2018 CU254_RS27785 d7bbaf4d4f2662a8cfcfd5c48bcb8371 396 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 23 136 7.0E-26 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS34405 f905c89c44b8e47e34c35c32c52ce504 395 Gene3D G3DSA:1.10.630.10 20 394 7.5E-72 T 28-03-2018 CU254_RS34405 f905c89c44b8e47e34c35c32c52ce504 395 Pfam PF00067 Cytochrome P450 263 362 4.7E-19 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS34405 f905c89c44b8e47e34c35c32c52ce504 395 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 334 343 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CU254_RS34405 f905c89c44b8e47e34c35c32c52ce504 395 PRINTS PR00359 B-class P450 signature 265 276 7.4E-58 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS34405 f905c89c44b8e47e34c35c32c52ce504 395 PRINTS PR00359 B-class P450 signature 332 341 7.4E-58 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS34405 f905c89c44b8e47e34c35c32c52ce504 395 PRINTS PR00359 B-class P450 signature 151 166 7.4E-58 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS34405 f905c89c44b8e47e34c35c32c52ce504 395 PRINTS PR00359 B-class P450 signature 188 210 7.4E-58 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS34405 f905c89c44b8e47e34c35c32c52ce504 395 PRINTS PR00359 B-class P450 signature 283 310 7.4E-58 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS34405 f905c89c44b8e47e34c35c32c52ce504 395 PRINTS PR00359 B-class P450 signature 341 352 7.4E-58 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS34405 f905c89c44b8e47e34c35c32c52ce504 395 PRINTS PR00359 B-class P450 signature 311 326 7.4E-58 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS34405 f905c89c44b8e47e34c35c32c52ce504 395 PRINTS PR00359 B-class P450 signature 87 98 7.4E-58 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS34405 f905c89c44b8e47e34c35c32c52ce504 395 PRINTS PR00359 B-class P450 signature 134 150 7.4E-58 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS34405 f905c89c44b8e47e34c35c32c52ce504 395 PRINTS PR00385 P450 superfamily signature 332 341 3.6E-7 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS34405 f905c89c44b8e47e34c35c32c52ce504 395 PRINTS PR00385 P450 superfamily signature 230 247 3.6E-7 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS34405 f905c89c44b8e47e34c35c32c52ce504 395 PRINTS PR00385 P450 superfamily signature 341 352 3.6E-7 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS34405 f905c89c44b8e47e34c35c32c52ce504 395 PRINTS PR00385 P450 superfamily signature 265 276 3.6E-7 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS34405 f905c89c44b8e47e34c35c32c52ce504 395 SUPERFAMILY SSF48264 21 394 8.38E-95 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS20140 6de1d98c05bcc8e434cb3503976d83ec 308 Gene3D G3DSA:3.30.565.10 186 308 1.6E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS20140 6de1d98c05bcc8e434cb3503976d83ec 308 Pfam PF13581 Histidine kinase-like ATPase domain 197 303 1.9E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS20140 6de1d98c05bcc8e434cb3503976d83ec 308 SUPERFAMILY SSF55874 213 303 8.63E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS20140 6de1d98c05bcc8e434cb3503976d83ec 308 Pfam PF14417 MEDS: MEthanogen/methylotroph, DcmR Sensory domain 9 152 2.9E-34 T 28-03-2018 IPR025847 MEDS domain CU254_RS00480 d6c27c751e872828b167dfd25d4af720 156 SUPERFAMILY SSF55811 6 146 2.71E-33 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CU254_RS00480 d6c27c751e872828b167dfd25d4af720 156 PRINTS PR00502 NUDIX hydrolase family signature 44 58 4.9E-7 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CU254_RS00480 d6c27c751e872828b167dfd25d4af720 156 PRINTS PR00502 NUDIX hydrolase family signature 58 73 4.9E-7 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CU254_RS00480 d6c27c751e872828b167dfd25d4af720 156 ProSitePatterns PS00893 Nudix box signature. 49 70 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CU254_RS00480 d6c27c751e872828b167dfd25d4af720 156 Pfam PF00293 NUDIX domain 20 132 6.8E-22 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CU254_RS00480 d6c27c751e872828b167dfd25d4af720 156 Gene3D G3DSA:3.90.79.10 9 153 3.7E-29 T 28-03-2018 CU254_RS27420 2f941997629804dbb17309b8be5ce0fe 213 SUPERFAMILY SSF48498 76 211 1.67E-28 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS27420 2f941997629804dbb17309b8be5ce0fe 213 Gene3D G3DSA:1.10.260.40 40 81 1.5E-9 T 28-03-2018 CU254_RS27420 2f941997629804dbb17309b8be5ce0fe 213 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 77 209 1.4E-22 T 28-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 CU254_RS27420 2f941997629804dbb17309b8be5ce0fe 213 Gene3D G3DSA:1.10.357.10 82 213 1.1E-27 T 28-03-2018 CU254_RS27420 2f941997629804dbb17309b8be5ce0fe 213 Gene3D G3DSA:1.10.10.60 4 39 4.8E-10 T 28-03-2018 CU254_RS27420 2f941997629804dbb17309b8be5ce0fe 213 PRINTS PR00400 Tetracycline repressor protein signature 103 126 2.8E-19 T 28-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 CU254_RS27420 2f941997629804dbb17309b8be5ce0fe 213 PRINTS PR00400 Tetracycline repressor protein signature 83 102 2.8E-19 T 28-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 CU254_RS27420 2f941997629804dbb17309b8be5ce0fe 213 PRINTS PR00400 Tetracycline repressor protein signature 139 158 2.8E-19 T 28-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 CU254_RS27420 2f941997629804dbb17309b8be5ce0fe 213 PRINTS PR00400 Tetracycline repressor protein signature 30 53 2.8E-19 T 28-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 CU254_RS27420 2f941997629804dbb17309b8be5ce0fe 213 PRINTS PR00400 Tetracycline repressor protein signature 192 206 2.8E-19 T 28-03-2018 IPR003012 Tetracycline transcriptional regulator, TetR GO:0045892|GO:0046677 CU254_RS27420 2f941997629804dbb17309b8be5ce0fe 213 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 64 1.8E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS27420 2f941997629804dbb17309b8be5ce0fe 213 SUPERFAMILY SSF46689 11 73 3.8E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS25510 aa26090a41da0b3436ab48e0405a2882 287 PRINTS PR00111 Alpha/beta hydrolase fold signature 102 115 2.0E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS25510 aa26090a41da0b3436ab48e0405a2882 287 PRINTS PR00111 Alpha/beta hydrolase fold signature 230 244 2.0E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS25510 aa26090a41da0b3436ab48e0405a2882 287 PRINTS PR00111 Alpha/beta hydrolase fold signature 53 68 2.0E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS25510 aa26090a41da0b3436ab48e0405a2882 287 PRINTS PR00111 Alpha/beta hydrolase fold signature 116 129 2.0E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS25510 aa26090a41da0b3436ab48e0405a2882 287 Pfam PF00561 alpha/beta hydrolase fold 27 274 1.5E-24 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS25510 aa26090a41da0b3436ab48e0405a2882 287 SUPERFAMILY SSF53474 5 286 2.28E-63 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS25510 aa26090a41da0b3436ab48e0405a2882 287 Gene3D G3DSA:3.40.50.1820 1 287 2.8E-48 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS25510 aa26090a41da0b3436ab48e0405a2882 287 PRINTS PR00412 Epoxide hydrolase signature 263 285 4.2E-15 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS25510 aa26090a41da0b3436ab48e0405a2882 287 PRINTS PR00412 Epoxide hydrolase signature 53 68 4.2E-15 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS25510 aa26090a41da0b3436ab48e0405a2882 287 PRINTS PR00412 Epoxide hydrolase signature 102 115 4.2E-15 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS25510 aa26090a41da0b3436ab48e0405a2882 287 PRINTS PR00412 Epoxide hydrolase signature 116 129 4.2E-15 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS25510 aa26090a41da0b3436ab48e0405a2882 287 PRINTS PR00412 Epoxide hydrolase signature 33 51 4.2E-15 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS13235 37a23c44efea0bdda7338f07a6f2d518 189 SUPERFAMILY SSF46689 5 74 4.64E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS13235 37a23c44efea0bdda7338f07a6f2d518 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 59 1.5E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS13235 37a23c44efea0bdda7338f07a6f2d518 189 Gene3D G3DSA:1.10.260.40 41 63 6.2E-11 T 28-03-2018 CU254_RS13235 37a23c44efea0bdda7338f07a6f2d518 189 Gene3D G3DSA:1.10.10.60 1 40 1.2E-13 T 28-03-2018 CU254_RS13235 37a23c44efea0bdda7338f07a6f2d518 189 SUPERFAMILY SSF48498 81 187 2.7E-7 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS13235 37a23c44efea0bdda7338f07a6f2d518 189 Gene3D G3DSA:1.10.357.10 64 189 7.5E-15 T 28-03-2018 CU254_RS05475 6b757d6e1da0c2472c96c068b237302e 298 Gene3D G3DSA:3.90.70.10 46 296 3.6E-28 T 28-03-2018 CU254_RS05475 6b757d6e1da0c2472c96c068b237302e 298 SUPERFAMILY SSF54001 64 280 1.61E-26 T 28-03-2018 CU254_RS05475 6b757d6e1da0c2472c96c068b237302e 298 Pfam PF00112 Papain family cysteine protease 136 276 8.4E-9 T 28-03-2018 IPR000668 Peptidase C1A, papain C-terminal GO:0006508|GO:0008234 CU254_RS01035 6dcc689bdbbe35c0cdc2433aa995eebc 208 SUPERFAMILY SSF46894 136 208 1.43E-5 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS01035 6dcc689bdbbe35c0cdc2433aa995eebc 208 Gene3D G3DSA:1.10.10.10 55 208 1.5E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS35340 6ac8b16f0125b291d14b7e75d13eb4ca 339 Gene3D G3DSA:3.40.190.10 54 167 1.4E-10 T 28-03-2018 CU254_RS35340 6ac8b16f0125b291d14b7e75d13eb4ca 339 Gene3D G3DSA:3.40.190.10 168 339 4.5E-27 T 28-03-2018 CU254_RS35340 6ac8b16f0125b291d14b7e75d13eb4ca 339 SUPERFAMILY SSF53850 57 271 2.2E-25 T 28-03-2018 CU254_RS35340 6ac8b16f0125b291d14b7e75d13eb4ca 339 Pfam PF13379 NMT1-like family 53 279 1.4E-16 T 28-03-2018 CU254_RS39605 c8b1d204f9c1d861b61b177365c43b17 496 SUPERFAMILY SSF53850 29 485 2.31E-112 T 28-03-2018 CU254_RS39605 c8b1d204f9c1d861b61b177365c43b17 496 Gene3D G3DSA:3.10.105.10 284 465 1.0E-39 T 28-03-2018 CU254_RS39605 c8b1d204f9c1d861b61b177365c43b17 496 Gene3D G3DSA:3.40.190.10 157 283 2.9E-37 T 28-03-2018 CU254_RS39605 c8b1d204f9c1d861b61b177365c43b17 496 PIRSF PIRSF002741 2 493 1.6E-85 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CU254_RS39605 c8b1d204f9c1d861b61b177365c43b17 496 Gene3D G3DSA:3.90.76.10 57 156 6.0E-27 T 28-03-2018 CU254_RS39605 c8b1d204f9c1d861b61b177365c43b17 496 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 76 403 1.0E-79 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CU254_RS35100 42ad626bb989ff2de40fff5a93cf0a59 75 Gene3D G3DSA:1.20.1070.10 4 75 5.0E-4 T 28-03-2018 CU254_RS35100 42ad626bb989ff2de40fff5a93cf0a59 75 Pfam PF10745 Protein of unknown function (DUF2530) 3 74 2.1E-30 T 28-03-2018 IPR019681 Protein of unknown function DUF2530 CU254_RS38690 d4b56af96e7b8526abbb682aa7d34d02 554 Pfam PF00474 Sodium:solute symporter family 43 452 9.4E-21 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CU254_RS13705 6b90fa82c30d2ca2d5675e6f74c083d7 364 Pfam PF02515 CoA-transferase family III 5 355 1.5E-80 T 28-03-2018 IPR003673 CoA-transferase family III GO:0003824 CU254_RS13705 6b90fa82c30d2ca2d5675e6f74c083d7 364 SUPERFAMILY SSF89796 3 363 1.57E-113 T 28-03-2018 IPR023606 CoA-transferase family III domain CU254_RS13705 6b90fa82c30d2ca2d5675e6f74c083d7 364 Gene3D G3DSA:3.40.50.10540 1 364 2.4E-113 T 28-03-2018 IPR023606 CoA-transferase family III domain CU254_RS08495 31f162a500c20ab02ab38462cc88973d 369 Pfam PF00487 Fatty acid desaturase 65 332 1.9E-34 T 28-03-2018 IPR005804 Fatty acid desaturase domain GO:0006629 CU254_RS30005 2125a088ec352035fefc110f9a54ce8e 325 Gene3D G3DSA:3.40.50.720 13 317 1.4E-45 T 28-03-2018 CU254_RS30005 2125a088ec352035fefc110f9a54ce8e 325 SUPERFAMILY SSF51735 14 316 1.79E-49 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS30005 2125a088ec352035fefc110f9a54ce8e 325 Pfam PF01370 NAD dependent epimerase/dehydratase family 14 229 1.8E-24 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CU254_RS35795 5bd614b4abb0c20e6e7c4fe276ebf9d5 423 Gene3D G3DSA:1.10.630.10 1 423 2.1E-75 T 28-03-2018 CU254_RS35795 5bd614b4abb0c20e6e7c4fe276ebf9d5 423 Pfam PF00067 Cytochrome P450 233 392 9.2E-25 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS35795 5bd614b4abb0c20e6e7c4fe276ebf9d5 423 SUPERFAMILY SSF48264 189 418 1.24E-89 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS35795 5bd614b4abb0c20e6e7c4fe276ebf9d5 423 SUPERFAMILY SSF48264 13 155 1.24E-89 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS35795 5bd614b4abb0c20e6e7c4fe276ebf9d5 423 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 367 376 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CU254_RS35795 5bd614b4abb0c20e6e7c4fe276ebf9d5 423 PRINTS PR00359 B-class P450 signature 316 343 9.7E-36 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS35795 5bd614b4abb0c20e6e7c4fe276ebf9d5 423 PRINTS PR00359 B-class P450 signature 299 310 9.7E-36 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS35795 5bd614b4abb0c20e6e7c4fe276ebf9d5 423 PRINTS PR00359 B-class P450 signature 365 374 9.7E-36 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS35795 5bd614b4abb0c20e6e7c4fe276ebf9d5 423 PRINTS PR00359 B-class P450 signature 83 94 9.7E-36 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS35795 5bd614b4abb0c20e6e7c4fe276ebf9d5 423 PRINTS PR00359 B-class P450 signature 344 359 9.7E-36 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS35795 5bd614b4abb0c20e6e7c4fe276ebf9d5 423 PRINTS PR00359 B-class P450 signature 374 385 9.7E-36 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS04650 5039d25f4bd979aafd9b239c329550de 283 Gene3D G3DSA:3.40.50.720 2 278 1.6E-63 T 28-03-2018 CU254_RS04650 5039d25f4bd979aafd9b239c329550de 283 Pfam PF00106 short chain dehydrogenase 4 187 5.4E-45 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS04650 5039d25f4bd979aafd9b239c329550de 283 SUPERFAMILY SSF51735 3 240 1.31E-59 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS04650 5039d25f4bd979aafd9b239c329550de 283 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 8.1E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS04650 5039d25f4bd979aafd9b239c329550de 283 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 128 136 8.1E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS04650 5039d25f4bd979aafd9b239c329550de 283 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 8.1E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS04650 5039d25f4bd979aafd9b239c329550de 283 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 9.6E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS04650 5039d25f4bd979aafd9b239c329550de 283 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 9.6E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS04650 5039d25f4bd979aafd9b239c329550de 283 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 9.6E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS04650 5039d25f4bd979aafd9b239c329550de 283 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 9.6E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS04650 5039d25f4bd979aafd9b239c329550de 283 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 9.6E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS05200 8e30c0d8d589a2433fe63f9c97ece5d2 289 Gene3D G3DSA:1.10.3720.10 4 276 6.9E-36 T 28-03-2018 CU254_RS05200 8e30c0d8d589a2433fe63f9c97ece5d2 289 SUPERFAMILY SSF161098 9 289 7.57E-63 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS05200 8e30c0d8d589a2433fe63f9c97ece5d2 289 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 279 2.1E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS40350 a11cc73485efb0e686f58053b9ae0793 196 Pfam PF12079 Protein of unknown function (DUF3558) 7 188 1.0E-22 T 28-03-2018 IPR024520 Protein of unknown function DUF3558 CU254_RS13205 7f7f9879f0b0397373910bd8c65c4807 366 SUPERFAMILY SSF53474 15 364 3.16E-89 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS13205 7f7f9879f0b0397373910bd8c65c4807 366 PIRSF PIRSF000443 1 366 6.5E-127 T 28-03-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 CU254_RS13205 7f7f9879f0b0397373910bd8c65c4807 366 Pfam PF00561 alpha/beta hydrolase fold 45 349 3.1E-29 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS13205 7f7f9879f0b0397373910bd8c65c4807 366 Gene3D G3DSA:3.40.50.1820 25 366 1.1E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS13205 7f7f9879f0b0397373910bd8c65c4807 366 TIGRFAM TIGR01392 homoserO_Ac_trn: homoserine O-acetyltransferase 17 363 9.9E-109 T 28-03-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 CU254_RS13205 7f7f9879f0b0397373910bd8c65c4807 366 Hamap MF_00296 Homoserine O-acetyltransferase [metX]. 2 365 42.386 T 28-03-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 CU254_RS20090 53cd37fe6b4ac2bfc3082f0b98fad624 328 SUPERFAMILY SSF161098 83 312 2.75E-51 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS20090 53cd37fe6b4ac2bfc3082f0b98fad624 328 Gene3D G3DSA:1.10.3720.10 37 322 5.2E-41 T 28-03-2018 CU254_RS20090 53cd37fe6b4ac2bfc3082f0b98fad624 328 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 317 1.4E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS21265 285027d7b9f4dca85121cc9cfc2baba0 283 Pfam PF14011 EspG family 11 276 2.9E-33 T 28-03-2018 IPR025734 EspG family CU254_RS17560 bea7fe646ac53b80a2b77762efdf2170 454 Gene3D G3DSA:3.90.1150.10 269 449 6.1E-35 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS17560 bea7fe646ac53b80a2b77762efdf2170 454 Pfam PF00202 Aminotransferase class-III 30 440 1.1E-90 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CU254_RS17560 bea7fe646ac53b80a2b77762efdf2170 454 Gene3D G3DSA:3.90.1150.10 187 268 1.2E-4 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS17560 bea7fe646ac53b80a2b77762efdf2170 454 SUPERFAMILY SSF53383 15 447 6.4E-117 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS17560 bea7fe646ac53b80a2b77762efdf2170 454 PIRSF PIRSF000521 24 397 3.0E-30 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CU254_RS17560 bea7fe646ac53b80a2b77762efdf2170 454 Gene3D G3DSA:3.90.1150.10 2 175 2.7E-42 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS29480 d8be0533b09bb261fe0f734f369e5867 159 Gene3D G3DSA:1.20.1290.10 1 152 1.0E-37 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CU254_RS29480 d8be0533b09bb261fe0f734f369e5867 159 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 31 80 6.1E-21 T 28-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CU254_RS29480 d8be0533b09bb261fe0f734f369e5867 159 SUPERFAMILY SSF69118 17 150 1.44E-42 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CU254_RS29480 d8be0533b09bb261fe0f734f369e5867 159 Pfam PF02627 Carboxymuconolactone decarboxylase family 17 96 3.3E-22 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CU254_RS40670 9db18706b36b69a55325a0ef3bf3af5f 770 TIGRFAM TIGR00702 TIGR00702: YcaO-type kinase domain 392 733 1.1E-26 T 28-03-2018 IPR003776 YcaO-like domain CU254_RS40670 9db18706b36b69a55325a0ef3bf3af5f 770 Gene3D G3DSA:3.40.50.720 106 327 6.5E-14 T 28-03-2018 CU254_RS40670 9db18706b36b69a55325a0ef3bf3af5f 770 Pfam PF02624 YcaO cyclodehydratase, ATP-ad Mg2+-binding 397 733 6.0E-91 T 28-03-2018 IPR003776 YcaO-like domain CU254_RS40670 9db18706b36b69a55325a0ef3bf3af5f 770 TIGRFAM TIGR03882 cyclo_dehyd_2: bacteriocin biosynthesis cyclodehydratase domain 271 356 3.2E-20 T 28-03-2018 IPR022291 Bacteriocin biosynthesis, cyclodehydratase domain CU254_RS40670 9db18706b36b69a55325a0ef3bf3af5f 770 TIGRFAM TIGR03882 cyclo_dehyd_2: bacteriocin biosynthesis cyclodehydratase domain 171 255 8.7E-15 T 28-03-2018 IPR022291 Bacteriocin biosynthesis, cyclodehydratase domain CU254_RS40670 9db18706b36b69a55325a0ef3bf3af5f 770 TIGRFAM TIGR03604 TOMM_cyclo_SagD: thiazole/oxazole-forming peptide maturase, SagD family component 398 766 2.4E-77 T 28-03-2018 IPR027624 Thiazole/oxazole-forming peptide maturase, SagD family component CU254_RS13490 23a7eac4976f9df2d86b38c52958ab2c 364 SUPERFAMILY SSF55347 129 286 9.16E-24 T 28-03-2018 CU254_RS13490 23a7eac4976f9df2d86b38c52958ab2c 364 Gene3D G3DSA:3.30.360.10 140 347 1.8E-28 T 28-03-2018 CU254_RS13490 23a7eac4976f9df2d86b38c52958ab2c 364 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 117 2.8E-17 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CU254_RS13490 23a7eac4976f9df2d86b38c52958ab2c 364 Gene3D G3DSA:3.40.50.720 2 139 1.3E-29 T 28-03-2018 CU254_RS13490 23a7eac4976f9df2d86b38c52958ab2c 364 SUPERFAMILY SSF51735 3 146 2.53E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS11970 3b6fe5e378319e3b9946bc167538b3f8 496 PRINTS PR00465 E-class P450 group IV signature 74 91 2.0E-23 T 28-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS11970 3b6fe5e378319e3b9946bc167538b3f8 496 PRINTS PR00465 E-class P450 group IV signature 354 370 2.0E-23 T 28-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS11970 3b6fe5e378319e3b9946bc167538b3f8 496 PRINTS PR00465 E-class P450 group IV signature 387 401 2.0E-23 T 28-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS11970 3b6fe5e378319e3b9946bc167538b3f8 496 PRINTS PR00465 E-class P450 group IV signature 444 462 2.0E-23 T 28-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS11970 3b6fe5e378319e3b9946bc167538b3f8 496 PRINTS PR00465 E-class P450 group IV signature 299 325 2.0E-23 T 28-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS11970 3b6fe5e378319e3b9946bc167538b3f8 496 PRINTS PR00465 E-class P450 group IV signature 403 421 2.0E-23 T 28-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS11970 3b6fe5e378319e3b9946bc167538b3f8 496 PRINTS PR00465 E-class P450 group IV signature 428 444 2.0E-23 T 28-03-2018 IPR002403 Cytochrome P450, E-class, group IV GO:0004497|GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS11970 3b6fe5e378319e3b9946bc167538b3f8 496 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 437 446 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CU254_RS11970 3b6fe5e378319e3b9946bc167538b3f8 496 PRINTS PR00385 P450 superfamily signature 308 325 1.9E-5 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS11970 3b6fe5e378319e3b9946bc167538b3f8 496 PRINTS PR00385 P450 superfamily signature 435 444 1.9E-5 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS11970 3b6fe5e378319e3b9946bc167538b3f8 496 PRINTS PR00385 P450 superfamily signature 359 370 1.9E-5 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS11970 3b6fe5e378319e3b9946bc167538b3f8 496 PRINTS PR00385 P450 superfamily signature 444 455 1.9E-5 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS11970 3b6fe5e378319e3b9946bc167538b3f8 496 SUPERFAMILY SSF48264 70 496 7.33E-93 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS11970 3b6fe5e378319e3b9946bc167538b3f8 496 Pfam PF00067 Cytochrome P450 269 471 1.8E-55 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS11970 3b6fe5e378319e3b9946bc167538b3f8 496 Pfam PF00067 Cytochrome P450 94 235 6.8E-7 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS11970 3b6fe5e378319e3b9946bc167538b3f8 496 Gene3D G3DSA:1.10.630.10 61 495 2.3E-99 T 28-03-2018 CU254_RS06120 834c1293402e8f23a86c3aa650f977cb 403 SUPERFAMILY SSF103473 7 386 7.85E-35 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS06120 834c1293402e8f23a86c3aa650f977cb 403 Gene3D G3DSA:1.20.1250.20 4 202 3.8E-17 T 28-03-2018 CU254_RS06120 834c1293402e8f23a86c3aa650f977cb 403 Pfam PF05977 Transmembrane secretion effector 4 387 9.2E-26 T 28-03-2018 IPR010290 Transmembrane secretion effector CU254_RS06120 834c1293402e8f23a86c3aa650f977cb 403 Gene3D G3DSA:1.20.1250.20 203 389 1.2E-10 T 28-03-2018 CU254_RS21140 a62cdcb035886cdc89dc15685a76a73e 300 SUPERFAMILY SSF52467 30 285 4.67E-70 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CU254_RS21140 a62cdcb035886cdc89dc15685a76a73e 300 Hamap MF_01967 NAD-dependent protein deacetylase [cobB]. 16 285 59.874 T 28-03-2018 IPR026587 Sirtuin, class II Reactome: R-HSA-2151201 CU254_RS21140 a62cdcb035886cdc89dc15685a76a73e 300 Gene3D G3DSA:3.40.50.1220 18 292 1.8E-61 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CU254_RS21140 a62cdcb035886cdc89dc15685a76a73e 300 Pfam PF02146 Sir2 family 39 240 3.9E-42 T 28-03-2018 IPR003000 Sirtuin family GO:0070403 CU254_RS03555 e1c88bc4ab729aa66e4136c351ac4c97 359 SUPERFAMILY SSF51161 257 351 4.88E-18 T 28-03-2018 IPR011004 Trimeric LpxA-like CU254_RS03555 e1c88bc4ab729aa66e4136c351ac4c97 359 Pfam PF00483 Nucleotidyl transferase 9 235 5.9E-42 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CU254_RS03555 e1c88bc4ab729aa66e4136c351ac4c97 359 SUPERFAMILY SSF53448 7 240 8.57E-68 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS03555 e1c88bc4ab729aa66e4136c351ac4c97 359 SUPERFAMILY SSF53448 301 317 8.57E-68 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS03555 e1c88bc4ab729aa66e4136c351ac4c97 359 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 288 321 2.5E-4 T 28-03-2018 IPR001451 Hexapeptide repeat CU254_RS03555 e1c88bc4ab729aa66e4136c351ac4c97 359 Gene3D G3DSA:3.90.550.10 2 237 5.7E-54 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS03555 e1c88bc4ab729aa66e4136c351ac4c97 359 Gene3D G3DSA:2.160.10.10 238 353 1.1E-19 T 28-03-2018 CU254_RS37365 b04f71c00919771835710ed46cab61cf 133 SUPERFAMILY SSF50475 15 131 3.93E-22 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS37365 b04f71c00919771835710ed46cab61cf 133 TIGRFAM TIGR03667 Rv3369: PPOX class probable F420-dependent enzyme, Rv3369 family 14 129 3.3E-40 T 28-03-2018 IPR019966 F420-dependent enzyme, PPOX class, family Rv3369, probable CU254_RS37365 b04f71c00919771835710ed46cab61cf 133 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 13 87 1.2E-13 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CU254_RS37365 b04f71c00919771835710ed46cab61cf 133 Gene3D G3DSA:2.30.110.10 8 131 3.7E-21 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS23215 8ef7ccfb40777629344693cce15c06f1 174 SUPERFAMILY SSF55729 3 164 3.72E-24 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS23215 8ef7ccfb40777629344693cce15c06f1 174 Gene3D G3DSA:3.40.630.30 1 163 6.8E-24 T 28-03-2018 CU254_RS23215 8ef7ccfb40777629344693cce15c06f1 174 Pfam PF00583 Acetyltransferase (GNAT) family 49 137 1.0E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS03910 b598d4628e6856c555bf09b5f6a0861a 186 Pfam PF03703 Bacterial PH domain 81 155 4.6E-14 T 28-03-2018 IPR005182 Domain of unknown function DUF304 CU254_RS40180 3635e0d6b27fde17aa150500e2e45589 426 Gene3D G3DSA:3.40.640.10 180 309 4.0E-38 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS40180 3635e0d6b27fde17aa150500e2e45589 426 SUPERFAMILY SSF53383 15 422 1.06E-108 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS40180 3635e0d6b27fde17aa150500e2e45589 426 PIRSF PIRSF000521 27 129 1.4E-6 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CU254_RS40180 3635e0d6b27fde17aa150500e2e45589 426 PIRSF PIRSF000521 124 425 1.8E-40 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CU254_RS40180 3635e0d6b27fde17aa150500e2e45589 426 Pfam PF00202 Aminotransferase class-III 25 420 8.0E-88 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CU254_RS40180 3635e0d6b27fde17aa150500e2e45589 426 Gene3D G3DSA:3.90.1150.10 310 426 5.0E-35 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS40180 3635e0d6b27fde17aa150500e2e45589 426 Gene3D G3DSA:3.90.1150.10 5 167 5.3E-36 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS29220 2736c6345b33ba4fef9c7d165fcb3194 586 SUPERFAMILY SSF161098 311 561 1.03E-35 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS29220 2736c6345b33ba4fef9c7d165fcb3194 586 SUPERFAMILY SSF161098 16 292 1.87E-46 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS29220 2736c6345b33ba4fef9c7d165fcb3194 586 Gene3D G3DSA:1.10.3720.10 305 563 1.1E-28 T 28-03-2018 CU254_RS29220 2736c6345b33ba4fef9c7d165fcb3194 586 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 391 561 3.7E-11 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS29220 2736c6345b33ba4fef9c7d165fcb3194 586 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 94 288 2.1E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS29220 2736c6345b33ba4fef9c7d165fcb3194 586 Gene3D G3DSA:1.10.3720.10 22 293 2.0E-32 T 28-03-2018 CU254_RS31165 610e6e05db9f5df4cb2b8b6156524564 219 Hamap MF_00722 Endonuclease NucS [nucS]. 1 211 31.563 T 28-03-2018 IPR002793 Endonuclease NucS CU254_RS31165 610e6e05db9f5df4cb2b8b6156524564 219 Pfam PF01939 Endonuclease NucS 2 219 2.8E-81 T 28-03-2018 IPR002793 Endonuclease NucS CU254_RS19035 526b8ffe95cedd7b4b168e6d06268bea 236 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 9.4E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS19035 526b8ffe95cedd7b4b168e6d06268bea 236 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 161 180 9.4E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS19035 526b8ffe95cedd7b4b168e6d06268bea 236 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 71 82 9.4E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS19035 526b8ffe95cedd7b4b168e6d06268bea 236 Gene3D G3DSA:3.40.50.720 2 232 1.5E-52 T 28-03-2018 CU254_RS19035 526b8ffe95cedd7b4b168e6d06268bea 236 Pfam PF00106 short chain dehydrogenase 3 199 1.8E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS19035 526b8ffe95cedd7b4b168e6d06268bea 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 71 82 5.4E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS19035 526b8ffe95cedd7b4b168e6d06268bea 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 5.4E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS19035 526b8ffe95cedd7b4b168e6d06268bea 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 5.4E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS19035 526b8ffe95cedd7b4b168e6d06268bea 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 5.4E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS19035 526b8ffe95cedd7b4b168e6d06268bea 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 5.4E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS19035 526b8ffe95cedd7b4b168e6d06268bea 236 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 148 176 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS19035 526b8ffe95cedd7b4b168e6d06268bea 236 SUPERFAMILY SSF51735 3 233 2.14E-52 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS01615 3da44cf1fb30619def54da24f7a4e15c 271 Gene3D G3DSA:1.10.1660.10 10 69 1.3E-20 T 28-03-2018 CU254_RS01615 3da44cf1fb30619def54da24f7a4e15c 271 Pfam PF13411 MerR HTH family regulatory protein 15 81 8.7E-13 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS01615 3da44cf1fb30619def54da24f7a4e15c 271 Gene3D G3DSA:1.10.1660.10 70 136 4.3E-12 T 28-03-2018 CU254_RS01615 3da44cf1fb30619def54da24f7a4e15c 271 SMART SM00422 14 83 2.9E-25 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS01615 3da44cf1fb30619def54da24f7a4e15c 271 SUPERFAMILY SSF89082 171 260 1.1E-18 T 28-03-2018 IPR012925 TipAS antibiotic-recognition domain CU254_RS01615 3da44cf1fb30619def54da24f7a4e15c 271 SUPERFAMILY SSF46955 14 121 1.06E-27 T 28-03-2018 IPR009061 Putative DNA-binding domain CU254_RS01615 3da44cf1fb30619def54da24f7a4e15c 271 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 26 1.6E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS01615 3da44cf1fb30619def54da24f7a4e15c 271 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 50 70 1.6E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS01615 3da44cf1fb30619def54da24f7a4e15c 271 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 26 39 1.6E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS01615 3da44cf1fb30619def54da24f7a4e15c 271 Gene3D G3DSA:1.10.490.50 172 261 1.7E-19 T 28-03-2018 CU254_RS01615 3da44cf1fb30619def54da24f7a4e15c 271 Pfam PF07739 TipAS antibiotic-recognition domain 144 256 4.2E-30 T 28-03-2018 IPR012925 TipAS antibiotic-recognition domain CU254_RS32025 b155bbd37257647040e19ee79db8638f 467 Gene3D G3DSA:1.20.1250.20 253 465 3.2E-28 T 28-03-2018 CU254_RS32025 b155bbd37257647040e19ee79db8638f 467 Pfam PF07690 Major Facilitator Superfamily 14 405 3.5E-47 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS32025 b155bbd37257647040e19ee79db8638f 467 SUPERFAMILY SSF103473 242 457 2.75E-62 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS32025 b155bbd37257647040e19ee79db8638f 467 SUPERFAMILY SSF103473 8 191 2.75E-62 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS32025 b155bbd37257647040e19ee79db8638f 467 Gene3D G3DSA:1.20.1250.20 6 192 6.5E-32 T 28-03-2018 CU254_RS15565 db43df6cd55736750f724d7a7bd328cb 762 Gene3D G3DSA:2.40.50.140 663 752 6.7E-8 T 28-03-2018 CU254_RS15565 db43df6cd55736750f724d7a7bd328cb 762 Pfam PF13520 Amino acid permease 44 448 1.1E-20 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CU254_RS10100 107705b0f136e493410b70bfb42689b7 363 PIRSF PIRSF001361 5 363 9.3E-155 T 28-03-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CU254_RS10100 107705b0f136e493410b70bfb42689b7 363 Pfam PF00793 DAHP synthetase I family 52 351 3.8E-93 T 28-03-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 CU254_RS10100 107705b0f136e493410b70bfb42689b7 363 Gene3D G3DSA:3.20.20.70 18 363 1.3E-123 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS10100 107705b0f136e493410b70bfb42689b7 363 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 16 362 5.7E-148 T 28-03-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CU254_RS10100 107705b0f136e493410b70bfb42689b7 363 SUPERFAMILY SSF51569 20 362 2.49E-128 T 28-03-2018 CU254_RS04020 a97f589bb19235298046b389a043797c 474 SUPERFAMILY SSF51905 4 193 6.11E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS04020 a97f589bb19235298046b389a043797c 474 SUPERFAMILY SSF51905 148 304 1.22E-28 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS04020 a97f589bb19235298046b389a043797c 474 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 295 4.2E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS04020 a97f589bb19235298046b389a043797c 474 Gene3D G3DSA:3.50.50.60 1 103 3.7E-14 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS04020 a97f589bb19235298046b389a043797c 474 Gene3D G3DSA:3.30.390.30 335 399 5.4E-6 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CU254_RS04020 a97f589bb19235298046b389a043797c 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 103 121 2.6E-18 T 28-03-2018 CU254_RS04020 a97f589bb19235298046b389a043797c 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 231 247 2.6E-18 T 28-03-2018 CU254_RS04020 a97f589bb19235298046b389a043797c 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 149 167 2.6E-18 T 28-03-2018 CU254_RS04020 a97f589bb19235298046b389a043797c 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 256 278 2.6E-18 T 28-03-2018 CU254_RS04020 a97f589bb19235298046b389a043797c 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 2.6E-18 T 28-03-2018 CU254_RS04020 a97f589bb19235298046b389a043797c 474 Gene3D G3DSA:3.50.50.60 104 240 1.4E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS04020 a97f589bb19235298046b389a043797c 474 Pfam PF04324 BFD-like [2Fe-2S] binding domain 421 465 2.2E-11 T 28-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain CU254_RS04020 a97f589bb19235298046b389a043797c 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 232 246 6.2E-12 T 28-03-2018 CU254_RS04020 a97f589bb19235298046b389a043797c 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 6.2E-12 T 28-03-2018 CU254_RS04020 a97f589bb19235298046b389a043797c 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 271 278 6.2E-12 T 28-03-2018 CU254_RS04020 a97f589bb19235298046b389a043797c 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 149 174 6.2E-12 T 28-03-2018 CU254_RS04020 a97f589bb19235298046b389a043797c 474 Gene3D G3DSA:3.50.50.60 241 334 2.2E-7 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS21730 d8bea4ccd95606fd3ac65ba4bcc41f09 282 SUPERFAMILY SSF53474 30 277 9.36E-30 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS21730 d8bea4ccd95606fd3ac65ba4bcc41f09 282 Pfam PF12697 Alpha/beta hydrolase family 74 221 2.5E-11 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS21730 d8bea4ccd95606fd3ac65ba4bcc41f09 282 Gene3D G3DSA:3.40.50.1820 18 276 1.2E-27 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS27370 e0966072c3950c670764b237ae31af4d 184 SUPERFAMILY SSF53597 2 178 5.89E-24 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CU254_RS27370 e0966072c3950c670764b237ae31af4d 184 Gene3D G3DSA:3.40.430.10 1 177 4.5E-27 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CU254_RS27370 e0966072c3950c670764b237ae31af4d 184 Pfam PF01872 RibD C-terminal domain 3 172 1.1E-18 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CU254_RS11280 7d9e6bdfd11d45836bfc9172199065ff 395 Gene3D G3DSA:3.30.200.20 22 130 5.6E-4 T 28-03-2018 CU254_RS11280 7d9e6bdfd11d45836bfc9172199065ff 395 Gene3D G3DSA:3.90.1200.10 135 380 1.7E-5 T 28-03-2018 CU254_RS11280 7d9e6bdfd11d45836bfc9172199065ff 395 SUPERFAMILY SSF56112 35 305 6.53E-13 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS35505 ca6c33c75a059ac3b60a592a4925ab82 252 Hamap MF_00443 Thiazole synthase [thiG]. 5 252 39.933 T 28-03-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 CU254_RS35505 ca6c33c75a059ac3b60a592a4925ab82 252 Pfam PF05690 Thiazole biosynthesis protein ThiG 8 250 1.3E-103 T 28-03-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 CU254_RS35505 ca6c33c75a059ac3b60a592a4925ab82 252 SUPERFAMILY SSF110399 4 242 9.02E-81 T 28-03-2018 CU254_RS35505 ca6c33c75a059ac3b60a592a4925ab82 252 Gene3D G3DSA:3.20.20.70 3 252 6.3E-52 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS32010 effa5cb9678588cf9cc9515e2ac7cb85 166 Pfam PF12903 Protein of unknown function (DUF3830) 7 164 1.3E-65 T 28-03-2018 IPR024532 Protein of unknown function DUF3830 CU254_RS32010 effa5cb9678588cf9cc9515e2ac7cb85 166 SUPERFAMILY SSF50891 6 151 3.3E-8 T 28-03-2018 IPR029000 Cyclophilin-like domain CU254_RS12080 b8381ff239d8be9bc90bf0651b776309 636 Gene3D G3DSA:2.70.98.20 185 634 1.3E-173 T 28-03-2018 IPR015798 Copper amine oxidase, C-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 CU254_RS12080 b8381ff239d8be9bc90bf0651b776309 636 Gene3D G3DSA:3.10.450.40 97 184 5.9E-29 T 28-03-2018 CU254_RS12080 b8381ff239d8be9bc90bf0651b776309 636 SUPERFAMILY SSF54416 5 93 7.85E-19 T 28-03-2018 IPR016182 Copper amine oxidase, N-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 CU254_RS12080 b8381ff239d8be9bc90bf0651b776309 636 Pfam PF02727 Copper amine oxidase, N2 domain 6 86 9.6E-9 T 28-03-2018 IPR015800 Copper amine oxidase, N2-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 CU254_RS12080 b8381ff239d8be9bc90bf0651b776309 636 ProSitePatterns PS01165 Copper amine oxidase copper-binding site signature. 591 604 - T 28-03-2018 IPR000269 Copper amine oxidase GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 CU254_RS12080 b8381ff239d8be9bc90bf0651b776309 636 Gene3D G3DSA:3.10.450.40 1 92 3.0E-23 T 28-03-2018 CU254_RS12080 b8381ff239d8be9bc90bf0651b776309 636 Pfam PF02728 Copper amine oxidase, N3 domain 94 193 3.4E-21 T 28-03-2018 IPR015802 Copper amine oxidase, N3-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 CU254_RS12080 b8381ff239d8be9bc90bf0651b776309 636 Pfam PF01179 Copper amine oxidase, enzyme domain 229 630 3.6E-154 T 28-03-2018 IPR015798 Copper amine oxidase, C-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 CU254_RS12080 b8381ff239d8be9bc90bf0651b776309 636 ProSitePatterns PS01164 Copper amine oxidase topaquinone signature. 378 391 - T 28-03-2018 IPR000269 Copper amine oxidase GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 CU254_RS12080 b8381ff239d8be9bc90bf0651b776309 636 SUPERFAMILY SSF54416 91 204 3.71E-34 T 28-03-2018 IPR016182 Copper amine oxidase, N-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 CU254_RS12080 b8381ff239d8be9bc90bf0651b776309 636 SUPERFAMILY SSF49998 221 631 2.88E-153 T 28-03-2018 IPR015798 Copper amine oxidase, C-terminal GO:0005507|GO:0008131|GO:0009308|GO:0048038|GO:0055114 Reactome: R-HSA-211945 CU254_RS03025 a5d63e16a974918ec4e7cf3ed0cf9770 341 PIRSF PIRSF000138 1 341 7.7E-126 T 28-03-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 CU254_RS03025 a5d63e16a974918ec4e7cf3ed0cf9770 341 Gene3D G3DSA:3.20.20.70 1 341 5.8E-107 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS03025 a5d63e16a974918ec4e7cf3ed0cf9770 341 SUPERFAMILY SSF51395 3 339 4.95E-94 T 28-03-2018 CU254_RS03025 a5d63e16a974918ec4e7cf3ed0cf9770 341 Pfam PF01070 FMN-dependent dehydrogenase 11 340 8.5E-126 T 28-03-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 CU254_RS03025 a5d63e16a974918ec4e7cf3ed0cf9770 341 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 238 244 - T 28-03-2018 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 CU254_RS38480 52c5ceb6a5b20f4f6a114314681eaf85 110 SUPERFAMILY SSF50129 11 98 1.08E-19 T 28-03-2018 IPR011032 GroES-like CU254_RS38480 52c5ceb6a5b20f4f6a114314681eaf85 110 Gene3D G3DSA:2.30.33.40 6 99 2.0E-21 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CU254_RS38480 52c5ceb6a5b20f4f6a114314681eaf85 110 Pfam PF00166 Chaperonin 10 Kd subunit 12 97 3.8E-19 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CU254_RS38480 52c5ceb6a5b20f4f6a114314681eaf85 110 PRINTS PR00297 10kDa chaperonin signature 38 59 1.6E-9 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CU254_RS38480 52c5ceb6a5b20f4f6a114314681eaf85 110 PRINTS PR00297 10kDa chaperonin signature 85 98 1.6E-9 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CU254_RS38480 52c5ceb6a5b20f4f6a114314681eaf85 110 PRINTS PR00297 10kDa chaperonin signature 12 27 1.6E-9 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CU254_RS38480 52c5ceb6a5b20f4f6a114314681eaf85 110 PRINTS PR00297 10kDa chaperonin signature 64 76 1.6E-9 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CU254_RS38480 52c5ceb6a5b20f4f6a114314681eaf85 110 SMART SM00883 11 98 8.4E-28 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CU254_RS24975 0a24ffc35f88e347aefe7764fa6beb2c 297 SUPERFAMILY SSF47240 153 293 6.49E-35 T 28-03-2018 IPR009078 Ferritin-like superfamily CU254_RS24975 0a24ffc35f88e347aefe7764fa6beb2c 297 Gene3D G3DSA:1.20.1260.10 154 286 3.6E-14 T 28-03-2018 IPR012347 Ferritin-related CU254_RS24975 0a24ffc35f88e347aefe7764fa6beb2c 297 Pfam PF14530 Domain of unknown function (DUF4439) 161 296 1.0E-36 T 28-03-2018 IPR029447 Domain of unknown function DUF4439 CU254_RS29015 28308bcd9bd5e1ee0249f46d1cef0064 292 SUPERFAMILY SSF103473 105 291 3.27E-23 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS29015 28308bcd9bd5e1ee0249f46d1cef0064 292 SUPERFAMILY SSF103473 2 57 3.27E-23 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS29015 28308bcd9bd5e1ee0249f46d1cef0064 292 Pfam PF07690 Major Facilitator Superfamily 2 257 1.3E-11 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS29015 28308bcd9bd5e1ee0249f46d1cef0064 292 Gene3D G3DSA:1.20.1250.20 1 62 3.5E-8 T 28-03-2018 CU254_RS29015 28308bcd9bd5e1ee0249f46d1cef0064 292 Gene3D G3DSA:1.20.1250.20 106 291 1.7E-13 T 28-03-2018 CU254_RS00320 854c4090d7b0b597473107f5e563cc72 438 Gene3D G3DSA:1.10.260.40 11 89 4.4E-13 T 28-03-2018 CU254_RS00320 854c4090d7b0b597473107f5e563cc72 438 Pfam PF13560 Helix-turn-helix domain 18 77 2.0E-13 T 28-03-2018 CU254_RS00320 854c4090d7b0b597473107f5e563cc72 438 SMART SM00530 21 76 4.7E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS00320 854c4090d7b0b597473107f5e563cc72 438 SUPERFAMILY SSF47413 15 71 3.26E-9 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS00320 854c4090d7b0b597473107f5e563cc72 438 Gene3D G3DSA:1.25.40.10 139 437 3.3E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS29475 50df8aefdc360639126468cc3c5923d8 321 SUPERFAMILY SSF103481 203 298 1.83E-10 T 28-03-2018 CU254_RS29475 50df8aefdc360639126468cc3c5923d8 321 Pfam PF00892 EamA-like transporter family 15 143 1.3E-15 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CU254_RS29475 50df8aefdc360639126468cc3c5923d8 321 Pfam PF00892 EamA-like transporter family 155 291 1.7E-14 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CU254_RS29475 50df8aefdc360639126468cc3c5923d8 321 SUPERFAMILY SSF103481 45 145 1.83E-14 T 28-03-2018 CU254_RS13720 a6a062d9e8c9d28fefe725de0deb64cc 424 Gene3D G3DSA:3.20.20.120 128 424 6.8E-101 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CU254_RS13720 a6a062d9e8c9d28fefe725de0deb64cc 424 SMART SM01192 139 424 1.1E-207 T 28-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CU254_RS13720 a6a062d9e8c9d28fefe725de0deb64cc 424 Hamap MF_00318 Enolase [eno]. 2 411 43.903 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CU254_RS13720 a6a062d9e8c9d28fefe725de0deb64cc 424 SUPERFAMILY SSF54826 4 138 4.09E-53 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CU254_RS13720 a6a062d9e8c9d28fefe725de0deb64cc 424 PRINTS PR00148 Enolase signature 37 51 8.5E-45 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CU254_RS13720 a6a062d9e8c9d28fefe725de0deb64cc 424 PRINTS PR00148 Enolase signature 107 123 8.5E-45 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CU254_RS13720 a6a062d9e8c9d28fefe725de0deb64cc 424 PRINTS PR00148 Enolase signature 363 380 8.5E-45 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CU254_RS13720 a6a062d9e8c9d28fefe725de0deb64cc 424 PRINTS PR00148 Enolase signature 161 174 8.5E-45 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CU254_RS13720 a6a062d9e8c9d28fefe725de0deb64cc 424 PRINTS PR00148 Enolase signature 311 322 8.5E-45 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CU254_RS13720 a6a062d9e8c9d28fefe725de0deb64cc 424 PRINTS PR00148 Enolase signature 334 348 8.5E-45 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CU254_RS13720 a6a062d9e8c9d28fefe725de0deb64cc 424 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 422 1.1E-202 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CU254_RS13720 a6a062d9e8c9d28fefe725de0deb64cc 424 SUPERFAMILY SSF51604 139 422 2.04E-123 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CU254_RS13720 a6a062d9e8c9d28fefe725de0deb64cc 424 Pfam PF03952 Enolase, N-terminal domain 4 134 1.4E-57 T 28-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CU254_RS13720 a6a062d9e8c9d28fefe725de0deb64cc 424 Gene3D G3DSA:3.30.390.10 3 127 1.7E-50 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CU254_RS13720 a6a062d9e8c9d28fefe725de0deb64cc 424 PIRSF PIRSF001400 1 424 2.2E-185 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CU254_RS13720 a6a062d9e8c9d28fefe725de0deb64cc 424 Pfam PF00113 Enolase, C-terminal TIM barrel domain 140 422 3.7E-124 T 28-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CU254_RS13720 a6a062d9e8c9d28fefe725de0deb64cc 424 ProSitePatterns PS00164 Enolase signature. 334 347 - T 28-03-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CU254_RS13720 a6a062d9e8c9d28fefe725de0deb64cc 424 SMART SM01193 4 134 6.7E-88 T 28-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CU254_RS10910 49e094d97859130388307c7fdf82d351 221 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 1.5E-7 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CU254_RS10910 49e094d97859130388307c7fdf82d351 221 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 1.5E-7 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CU254_RS10910 49e094d97859130388307c7fdf82d351 221 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 1.5E-7 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CU254_RS10910 49e094d97859130388307c7fdf82d351 221 PRINTS PR00335 TrkA potassium uptake protein signature 60 70 1.5E-7 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CU254_RS10910 49e094d97859130388307c7fdf82d351 221 SUPERFAMILY SSF116726 142 211 3.92E-6 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CU254_RS10910 49e094d97859130388307c7fdf82d351 221 Gene3D G3DSA:3.40.50.720 1 118 1.9E-19 T 28-03-2018 CU254_RS10910 49e094d97859130388307c7fdf82d351 221 Pfam PF02254 TrkA-N domain 3 116 1.2E-23 T 28-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CU254_RS10910 49e094d97859130388307c7fdf82d351 221 SUPERFAMILY SSF51735 2 139 6.62E-27 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS10910 49e094d97859130388307c7fdf82d351 221 Gene3D G3DSA:3.30.70.1450 143 219 7.7E-8 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CU254_RS02975 5f9958b96bf96603ab35e8774dbe36a6 288 Pfam PF00171 Aldehyde dehydrogenase family 30 255 2.6E-37 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CU254_RS02975 5f9958b96bf96603ab35e8774dbe36a6 288 Gene3D G3DSA:3.40.605.10 7 268 3.8E-54 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CU254_RS02975 5f9958b96bf96603ab35e8774dbe36a6 288 SUPERFAMILY SSF53720 7 254 1.17E-41 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CU254_RS29550 1e765346f976adade1376621b936fb6d 464 PIRSF PIRSF006060 2 458 2.4E-56 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CU254_RS29550 1e765346f976adade1376621b936fb6d 464 Pfam PF13520 Amino acid permease 12 423 2.9E-34 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CU254_RS23985 6e9b0578e97bc5eb239516588488de28 411 SUPERFAMILY SSF51395 14 268 2.59E-91 T 28-03-2018 CU254_RS23985 6e9b0578e97bc5eb239516588488de28 411 SUPERFAMILY SSF51395 302 387 2.59E-91 T 28-03-2018 CU254_RS23985 6e9b0578e97bc5eb239516588488de28 411 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 14 240 3.4E-45 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CU254_RS23985 6e9b0578e97bc5eb239516588488de28 411 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 313 366 1.8E-4 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CU254_RS23985 6e9b0578e97bc5eb239516588488de28 411 Gene3D G3DSA:3.20.20.70 6 401 2.2E-93 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS40795 132d1572dc4ef31a670e5d09fd9e58ba 320 SUPERFAMILY SSF46785 5 63 5.96E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS40795 132d1572dc4ef31a670e5d09fd9e58ba 320 Pfam PF13280 WYL domain 143 312 1.5E-30 T 28-03-2018 IPR026881 WYL domain CU254_RS40795 132d1572dc4ef31a670e5d09fd9e58ba 320 Pfam PF08279 HTH domain 7 62 1.6E-15 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 CU254_RS40795 132d1572dc4ef31a670e5d09fd9e58ba 320 ProSitePatterns PS00894 DeoR-type HTH domain signature. 7 41 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CU254_RS40795 132d1572dc4ef31a670e5d09fd9e58ba 320 Gene3D G3DSA:1.10.10.10 2 66 8.3E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS39920 fbc4ca52cd0bdd7ea257ade3e67eeee9 434 Pfam PF06580 Histidine kinase 194 272 3.4E-25 T 28-03-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 CU254_RS39920 fbc4ca52cd0bdd7ea257ade3e67eeee9 434 Gene3D G3DSA:3.30.565.10 161 390 5.1E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS39920 fbc4ca52cd0bdd7ea257ade3e67eeee9 434 SMART SM00387 283 390 1.8E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS39920 fbc4ca52cd0bdd7ea257ade3e67eeee9 434 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 291 390 1.0E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS39920 fbc4ca52cd0bdd7ea257ade3e67eeee9 434 SUPERFAMILY SSF55874 249 389 1.83E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS12795 ce4e0f8694ddb35487b0773497dda7cb 217 Gene3D G3DSA:1.20.120.530 57 216 6.5E-36 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS12795 ce4e0f8694ddb35487b0773497dda7cb 217 Pfam PF07729 FCD domain 77 198 4.2E-28 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS12795 ce4e0f8694ddb35487b0773497dda7cb 217 Gene3D G3DSA:1.10.10.10 1 54 1.9E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS12795 ce4e0f8694ddb35487b0773497dda7cb 217 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 12 26 1.9E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS12795 ce4e0f8694ddb35487b0773497dda7cb 217 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 26 42 1.9E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS12795 ce4e0f8694ddb35487b0773497dda7cb 217 SUPERFAMILY SSF46785 2 56 7.11E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS12795 ce4e0f8694ddb35487b0773497dda7cb 217 SMART SM00345 1 52 5.9E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS12795 ce4e0f8694ddb35487b0773497dda7cb 217 SMART SM00895 77 199 1.1E-28 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS12795 ce4e0f8694ddb35487b0773497dda7cb 217 SUPERFAMILY SSF48008 74 206 4.71E-32 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS12795 ce4e0f8694ddb35487b0773497dda7cb 217 Pfam PF00392 Bacterial regulatory proteins, gntR family 1 51 2.0E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS18845 dc0b2e190818ab6a7747174c9a16f5ce 380 Gene3D G3DSA:2.60.120.10 194 359 1.9E-20 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS18845 dc0b2e190818ab6a7747174c9a16f5ce 380 Pfam PF07883 Cupin domain 268 336 1.6E-10 T 28-03-2018 IPR013096 Cupin 2, conserved barrel CU254_RS18845 dc0b2e190818ab6a7747174c9a16f5ce 380 Gene3D G3DSA:2.60.120.10 38 186 1.3E-9 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS18845 dc0b2e190818ab6a7747174c9a16f5ce 380 SUPERFAMILY SSF51182 28 351 8.32E-31 T 28-03-2018 IPR011051 RmlC-like cupin domain CU254_RS37585 c339cfa1e55b001ecbbecd3d2278a930 142 Gene3D G3DSA:3.30.160.20 4 142 1.3E-35 T 28-03-2018 CU254_RS37585 c339cfa1e55b001ecbbecd3d2278a930 142 Pfam PF00472 RF-1 domain 12 136 3.4E-22 T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CU254_RS37585 c339cfa1e55b001ecbbecd3d2278a930 142 SUPERFAMILY SSF75620 11 104 1.8E-10 T 28-03-2018 CU254_RS38190 d76d73b9f5dc5de7a7b0422f63f081ed 219 SUPERFAMILY SSF75217 52 213 3.14E-38 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CU254_RS38190 d76d73b9f5dc5de7a7b0422f63f081ed 219 Gene3D G3DSA:3.40.1280.10 52 218 5.6E-51 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CU254_RS38190 d76d73b9f5dc5de7a7b0422f63f081ed 219 Pfam PF00588 SpoU rRNA Methylase family 70 206 1.2E-24 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CU254_RS06710 fc09c1564737d7ccce5115c2b45a8af1 279 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 5 275 2.6E-69 T 28-03-2018 IPR003797 DegV CU254_RS06710 fc09c1564737d7ccce5115c2b45a8af1 279 Gene3D G3DSA:3.30.1180.10 151 279 1.7E-35 T 28-03-2018 CU254_RS06710 fc09c1564737d7ccce5115c2b45a8af1 279 Pfam PF02645 Uncharacterised protein, DegV family COG1307 5 277 3.1E-67 T 28-03-2018 IPR003797 DegV CU254_RS06710 fc09c1564737d7ccce5115c2b45a8af1 279 SUPERFAMILY SSF82549 4 275 2.17E-62 T 28-03-2018 CU254_RS06710 fc09c1564737d7ccce5115c2b45a8af1 279 Gene3D G3DSA:3.40.50.10170 1 149 1.2E-40 T 28-03-2018 CU254_RS26575 80cae698c85800cf0fc10f37af1e539e 235 SUPERFAMILY SSF48498 86 234 1.22E-20 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS26575 80cae698c85800cf0fc10f37af1e539e 235 Gene3D G3DSA:1.10.10.60 2 49 5.1E-12 T 28-03-2018 CU254_RS26575 80cae698c85800cf0fc10f37af1e539e 235 Gene3D G3DSA:1.10.357.10 98 235 4.8E-25 T 28-03-2018 CU254_RS26575 80cae698c85800cf0fc10f37af1e539e 235 Pfam PF00440 Bacterial regulatory proteins, tetR family 28 70 8.1E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS26575 80cae698c85800cf0fc10f37af1e539e 235 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 87 232 1.2E-13 T 28-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 CU254_RS26575 80cae698c85800cf0fc10f37af1e539e 235 SUPERFAMILY SSF46689 17 80 1.23E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS26575 80cae698c85800cf0fc10f37af1e539e 235 Gene3D G3DSA:1.10.260.40 50 97 1.4E-9 T 28-03-2018 CU254_RS32130 4f771cb0d9b3d306b2bd13b62c88aed2 169 SUPERFAMILY SSF55729 1 156 2.92E-20 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS32130 4f771cb0d9b3d306b2bd13b62c88aed2 169 Gene3D G3DSA:3.40.630.30 1 164 1.2E-19 T 28-03-2018 CU254_RS32130 4f771cb0d9b3d306b2bd13b62c88aed2 169 Pfam PF00583 Acetyltransferase (GNAT) family 39 147 7.6E-8 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS31215 c8c47a3cc9f9bd7d7b1d10f95768be18 396 Gene3D G3DSA:1.20.1440.110 10 118 4.1E-32 T 28-03-2018 CU254_RS31215 c8c47a3cc9f9bd7d7b1d10f95768be18 396 SUPERFAMILY SSF53474 293 396 1.27E-60 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS31215 c8c47a3cc9f9bd7d7b1d10f95768be18 396 SUPERFAMILY SSF53474 12 258 1.27E-60 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS31215 c8c47a3cc9f9bd7d7b1d10f95768be18 396 Pfam PF06500 Alpha/beta hydrolase of unknown function (DUF1100) 48 248 1.7E-9 T 28-03-2018 IPR010520 UPF0255 family CU254_RS31215 c8c47a3cc9f9bd7d7b1d10f95768be18 396 Gene3D G3DSA:3.40.50.1820 120 396 2.9E-31 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS17120 5e0b1bae84569e4e7db25c77471d4469 267 SUPERFAMILY SSF51735 1 241 6.06E-60 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS17120 5e0b1bae84569e4e7db25c77471d4469 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 180 2.4E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS17120 5e0b1bae84569e4e7db25c77471d4469 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 142 161 2.4E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS17120 5e0b1bae84569e4e7db25c77471d4469 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 69 80 2.4E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS17120 5e0b1bae84569e4e7db25c77471d4469 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 116 132 2.4E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS17120 5e0b1bae84569e4e7db25c77471d4469 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 1 16 2.4E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS17120 5e0b1bae84569e4e7db25c77471d4469 267 Pfam PF00106 short chain dehydrogenase 2 184 7.9E-47 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS17120 5e0b1bae84569e4e7db25c77471d4469 267 Gene3D G3DSA:3.40.50.720 1 265 4.7E-61 T 28-03-2018 CU254_RS17120 5e0b1bae84569e4e7db25c77471d4469 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 122 130 3.7E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS17120 5e0b1bae84569e4e7db25c77471d4469 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 69 80 3.7E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS17120 5e0b1bae84569e4e7db25c77471d4469 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 161 3.7E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS22880 9ecb38cdfc4c31516d8328f4f3b5bd41 146 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 28 139 1.2E-24 T 28-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 CU254_RS22880 9ecb38cdfc4c31516d8328f4f3b5bd41 146 SUPERFAMILY SSF54637 18 143 6.23E-26 T 28-03-2018 IPR029069 HotDog domain CU254_RS22880 9ecb38cdfc4c31516d8328f4f3b5bd41 146 Gene3D G3DSA:3.10.129.10 16 145 1.1E-25 T 28-03-2018 CU254_RS22880 9ecb38cdfc4c31516d8328f4f3b5bd41 146 Pfam PF03061 Thioesterase superfamily 54 130 4.2E-12 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CU254_RS08975 349a4beebdb69231bd36cfb666d336ae 241 PIRSF PIRSF006755 1 212 1.9E-37 T 28-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 CU254_RS08975 349a4beebdb69231bd36cfb666d336ae 241 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 6 170 2.7E-32 T 28-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 CU254_RS08975 349a4beebdb69231bd36cfb666d336ae 241 Gene3D G3DSA:3.40.50.300 2 213 4.4E-49 T 28-03-2018 CU254_RS08975 349a4beebdb69231bd36cfb666d336ae 241 Pfam PF13500 AAA domain 3 201 1.3E-38 T 28-03-2018 CU254_RS08975 349a4beebdb69231bd36cfb666d336ae 241 SUPERFAMILY SSF52540 3 202 1.69E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS08975 349a4beebdb69231bd36cfb666d336ae 241 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 1 204 23.872 T 28-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 CU254_RS12380 44e2b0136ec5823d382a82fddb51ff7f 111 Gene3D G3DSA:3.90.56.10 11 102 2.0E-29 T 28-03-2018 IPR003454 Monooxygenase component MmoB/DmpM GO:0004497|GO:0006725 CU254_RS12380 44e2b0136ec5823d382a82fddb51ff7f 111 Pfam PF02406 MmoB/DmpM family 14 100 5.3E-24 T 28-03-2018 IPR003454 Monooxygenase component MmoB/DmpM GO:0004497|GO:0006725 CU254_RS12380 44e2b0136ec5823d382a82fddb51ff7f 111 ProDom PD004249 MONOOXYGENASE COMPONENT HYDROXYLASE MMOB/DMPM PHENOL SUBUNIT 3D-STRUCTURE HYDROCARBONS IRON PHENOLHYDROXYLASE 35 100 4.0E-16 T 28-03-2018 IPR003454 Monooxygenase component MmoB/DmpM GO:0004497|GO:0006725 CU254_RS12380 44e2b0136ec5823d382a82fddb51ff7f 111 SUPERFAMILY SSF56029 9 102 1.44E-24 T 28-03-2018 IPR003454 Monooxygenase component MmoB/DmpM GO:0004497|GO:0006725 CU254_RS21960 ef42abea9b4a5f149d65d1c9819774fd 271 Pfam PF00722 Glycosyl hydrolases family 16 77 268 3.2E-43 T 28-03-2018 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 CU254_RS21960 ef42abea9b4a5f149d65d1c9819774fd 271 Gene3D G3DSA:2.60.120.200 34 270 9.0E-74 T 28-03-2018 CU254_RS21960 ef42abea9b4a5f149d65d1c9819774fd 271 SUPERFAMILY SSF49899 29 270 3.53E-73 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CU254_RS23580 7feff21e8ddee44593dc8b1f92f9ffcb 315 Gene3D G3DSA:1.20.1630.10 15 287 3.1E-45 T 28-03-2018 CU254_RS23580 7feff21e8ddee44593dc8b1f92f9ffcb 315 Pfam PF03916 Polysulphide reductase, NrfD 36 190 2.8E-11 T 28-03-2018 IPR005614 NrfD family CU254_RS17875 d8bd434e365ee3eca38645742765eb10 223 Gene3D G3DSA:3.40.190.10 31 222 1.3E-4 T 28-03-2018 CU254_RS17875 d8bd434e365ee3eca38645742765eb10 223 Pfam PF13531 Bacterial extracellular solute-binding protein 85 162 3.0E-8 T 28-03-2018 CU254_RS30235 ac69a66c328882f8eb55d79f6cb45638 140 Gene3D G3DSA:3.40.630.30 3 128 9.8E-22 T 28-03-2018 CU254_RS30235 ac69a66c328882f8eb55d79f6cb45638 140 Pfam PF13673 Acetyltransferase (GNAT) domain 29 129 7.5E-14 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS30235 ac69a66c328882f8eb55d79f6cb45638 140 SUPERFAMILY SSF55729 22 124 4.99E-21 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS23940 2fc9f54d1cb72e30ae9f635600970357 352 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 219 339 5.1E-25 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS23940 2fc9f54d1cb72e30ae9f635600970357 352 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 101 4.4E-13 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS23940 2fc9f54d1cb72e30ae9f635600970357 352 Gene3D G3DSA:1.10.540.10 1 117 5.0E-20 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS23940 2fc9f54d1cb72e30ae9f635600970357 352 Gene3D G3DSA:1.20.140.10 210 336 1.9E-31 T 28-03-2018 CU254_RS23940 2fc9f54d1cb72e30ae9f635600970357 352 SUPERFAMILY SSF47203 217 348 1.8E-34 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS23940 2fc9f54d1cb72e30ae9f635600970357 352 SUPERFAMILY SSF56645 1 178 2.23E-22 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS08855 e5df981f3c85a0a02320b911b897e5e1 315 SUPERFAMILY SSF81464 23 125 9.32E-18 T 28-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CU254_RS08855 e5df981f3c85a0a02320b911b897e5e1 315 Gene3D G3DSA:1.10.287.90 37 127 6.0E-19 T 28-03-2018 CU254_RS08855 e5df981f3c85a0a02320b911b897e5e1 315 Gene3D G3DSA:2.60.40.420 128 309 2.7E-42 T 28-03-2018 IPR008972 Cupredoxin CU254_RS08855 e5df981f3c85a0a02320b911b897e5e1 315 SUPERFAMILY SSF49503 131 277 6.59E-36 T 28-03-2018 IPR008972 Cupredoxin CU254_RS08855 e5df981f3c85a0a02320b911b897e5e1 315 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 196 249 - T 28-03-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CU254_RS08855 e5df981f3c85a0a02320b911b897e5e1 315 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 140 255 1.4E-15 T 28-03-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CU254_RS41170 fdadc878979e891c359610a8175444ac 527 Pfam PF00817 impB/mucB/samB family 19 146 3.1E-12 T 28-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CU254_RS41170 fdadc878979e891c359610a8175444ac 527 Gene3D G3DSA:1.10.150.20 154 230 7.5E-11 T 28-03-2018 CU254_RS41170 fdadc878979e891c359610a8175444ac 527 SUPERFAMILY SSF56672 2 224 1.07E-32 T 28-03-2018 CU254_RS41170 fdadc878979e891c359610a8175444ac 527 Gene3D G3DSA:3.30.70.270 34 93 0.0022 T 28-03-2018 CU254_RS15370 cfcba9be47f452ab4e4d139fbfa88356 212 Gene3D G3DSA:1.10.3210.10 17 171 2.5E-13 T 28-03-2018 CU254_RS15370 cfcba9be47f452ab4e4d139fbfa88356 212 Pfam PF01966 HD domain 32 117 1.3E-7 T 28-03-2018 IPR006674 HD domain CU254_RS15370 cfcba9be47f452ab4e4d139fbfa88356 212 SUPERFAMILY SSF109604 29 129 2.83E-15 T 28-03-2018 CU254_RS12900 e8d6de92ed2f7eef8d340245433a9e26 74 Gene3D G3DSA:2.40.50.100 1 71 1.9E-15 T 28-03-2018 CU254_RS12900 e8d6de92ed2f7eef8d340245433a9e26 74 Pfam PF00364 Biotin-requiring enzyme 12 69 7.0E-14 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CU254_RS12900 e8d6de92ed2f7eef8d340245433a9e26 74 SUPERFAMILY SSF51230 3 69 1.57E-16 T 28-03-2018 IPR011053 Single hybrid motif CU254_RS03525 56b0fe4e9490a3275626fd1c6332a848 376 Gene3D G3DSA:3.40.50.2000 180 349 4.2E-33 T 28-03-2018 CU254_RS03525 56b0fe4e9490a3275626fd1c6332a848 376 Gene3D G3DSA:3.40.50.2000 5 179 9.8E-10 T 28-03-2018 CU254_RS03525 56b0fe4e9490a3275626fd1c6332a848 376 Pfam PF13439 Glycosyltransferase Family 4 13 173 3.4E-19 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CU254_RS03525 56b0fe4e9490a3275626fd1c6332a848 376 SUPERFAMILY SSF53756 8 368 2.25E-62 T 28-03-2018 CU254_RS03525 56b0fe4e9490a3275626fd1c6332a848 376 Pfam PF00534 Glycosyl transferases group 1 194 347 8.9E-18 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CU254_RS30900 4b63042e70f4905f8a49fefd8b7aff4d 299 SMART SM00849 34 227 2.9E-14 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS30900 4b63042e70f4905f8a49fefd8b7aff4d 299 Pfam PF00753 Metallo-beta-lactamase superfamily 34 227 5.9E-15 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS30900 4b63042e70f4905f8a49fefd8b7aff4d 299 SUPERFAMILY SSF56281 12 268 1.82E-39 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS30900 4b63042e70f4905f8a49fefd8b7aff4d 299 Gene3D G3DSA:3.60.15.10 10 253 2.2E-23 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS01690 1a46417a0858e18b462e841a7cd04790 54 ProSitePatterns PS00582 Ribosomal protein L33 signature. 22 41 - T 28-03-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS01690 1a46417a0858e18b462e841a7cd04790 54 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 6 54 19.517 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS01690 1a46417a0858e18b462e841a7cd04790 54 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 2 54 2.5E-20 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS01690 1a46417a0858e18b462e841a7cd04790 54 Pfam PF00471 Ribosomal protein L33 9 54 2.2E-22 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS01690 1a46417a0858e18b462e841a7cd04790 54 SUPERFAMILY SSF57829 4 54 1.04E-19 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CU254_RS10530 54fc59941b8fcc0dd9ebfca4ca7bb815 271 Pfam PF00561 alpha/beta hydrolase fold 29 135 1.7E-16 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS10530 54fc59941b8fcc0dd9ebfca4ca7bb815 271 Gene3D G3DSA:3.40.50.1820 14 271 1.3E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS10530 54fc59941b8fcc0dd9ebfca4ca7bb815 271 SUPERFAMILY SSF53474 9 269 2.96E-33 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS28310 1ab90176e1a0adc6718566a82972985e 201 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 9 190 5.9E-71 T 28-03-2018 IPR004507 Flavin prenyltransferase UbiX/Pad1 CU254_RS28310 1ab90176e1a0adc6718566a82972985e 201 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 8 192 38.036 T 28-03-2018 IPR004507 Flavin prenyltransferase UbiX/Pad1 CU254_RS28310 1ab90176e1a0adc6718566a82972985e 201 Pfam PF02441 Flavoprotein 9 170 1.8E-23 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CU254_RS28310 1ab90176e1a0adc6718566a82972985e 201 SUPERFAMILY SSF52507 9 192 4.32E-61 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CU254_RS28310 1ab90176e1a0adc6718566a82972985e 201 Gene3D G3DSA:3.40.50.1950 8 200 4.1E-55 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CU254_RS09450 58ed3750833639c947ee26d2ca409fbd 307 SUPERFAMILY SSF48576 17 299 4.46E-76 T 28-03-2018 IPR008949 Isoprenoid synthase domain CU254_RS09450 58ed3750833639c947ee26d2ca409fbd 307 Pfam PF00494 Squalene/phytoene synthase 27 285 1.2E-67 T 28-03-2018 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 CU254_RS09450 58ed3750833639c947ee26d2ca409fbd 307 ProSitePatterns PS01045 Squalene and phytoene synthases signature 2. 169 194 - T 28-03-2018 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CU254_RS09450 58ed3750833639c947ee26d2ca409fbd 307 Gene3D G3DSA:1.10.600.10 6 303 3.7E-93 T 28-03-2018 IPR008949 Isoprenoid synthase domain CU254_RS07415 b97795fc79cc3be8808009a05a2b49bd 195 Pfam PF12840 Helix-turn-helix domain 12 66 2.6E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS07415 b97795fc79cc3be8808009a05a2b49bd 195 Gene3D G3DSA:1.10.10.10 3 169 4.4E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS07415 b97795fc79cc3be8808009a05a2b49bd 195 SUPERFAMILY SSF46785 12 118 4.89E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS07415 b97795fc79cc3be8808009a05a2b49bd 195 SMART SM00418 13 109 1.7E-5 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS24180 df1b0d88eae4dea3e418fca655c8736c 356 Gene3D G3DSA:1.10.540.10 4 115 2.6E-22 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS24180 df1b0d88eae4dea3e418fca655c8736c 356 SUPERFAMILY SSF56645 7 187 5.5E-32 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS24180 df1b0d88eae4dea3e418fca655c8736c 356 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 116 1.1E-17 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS24180 df1b0d88eae4dea3e418fca655c8736c 356 Gene3D G3DSA:2.40.110.10 116 203 0.0018 T 28-03-2018 CU254_RS24180 df1b0d88eae4dea3e418fca655c8736c 356 SUPERFAMILY SSF47203 213 349 1.77E-29 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS24180 df1b0d88eae4dea3e418fca655c8736c 356 Gene3D G3DSA:1.20.140.10 204 353 7.3E-26 T 28-03-2018 CU254_RS24180 df1b0d88eae4dea3e418fca655c8736c 356 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 212 348 1.5E-22 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS12375 3f707ab264883ded317aacaed90932d8 84 Gene3D G3DSA:3.10.20.270 1 84 3.0E-31 T 28-03-2018 IPR009355 Toluene-4-monooxygenase system B CU254_RS12375 3f707ab264883ded317aacaed90932d8 84 Pfam PF06234 Toluene-4-monooxygenase system protein B (TmoB) 4 83 3.9E-25 T 28-03-2018 IPR009355 Toluene-4-monooxygenase system B CU254_RS12375 3f707ab264883ded317aacaed90932d8 84 SUPERFAMILY SSF110814 4 84 7.72E-21 T 28-03-2018 IPR009355 Toluene-4-monooxygenase system B CU254_RS38020 f0ffb8d9ae76d8f5f5d70e85e1c09a60 296 SUPERFAMILY SSF51735 5 260 4.56E-59 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS38020 f0ffb8d9ae76d8f5f5d70e85e1c09a60 296 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 183 3.1E-4 T 28-03-2018 CU254_RS38020 f0ffb8d9ae76d8f5f5d70e85e1c09a60 296 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS38020 f0ffb8d9ae76d8f5f5d70e85e1c09a60 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 5.1E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS38020 f0ffb8d9ae76d8f5f5d70e85e1c09a60 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 5.1E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS38020 f0ffb8d9ae76d8f5f5d70e85e1c09a60 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 5.1E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS38020 f0ffb8d9ae76d8f5f5d70e85e1c09a60 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 5.1E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS38020 f0ffb8d9ae76d8f5f5d70e85e1c09a60 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 5.1E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS38020 f0ffb8d9ae76d8f5f5d70e85e1c09a60 296 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 7.8E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS38020 f0ffb8d9ae76d8f5f5d70e85e1c09a60 296 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 7.8E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS38020 f0ffb8d9ae76d8f5f5d70e85e1c09a60 296 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 7.8E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS38020 f0ffb8d9ae76d8f5f5d70e85e1c09a60 296 Pfam PF00106 short chain dehydrogenase 9 195 1.3E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS38020 f0ffb8d9ae76d8f5f5d70e85e1c09a60 296 Gene3D G3DSA:3.40.50.720 2 222 1.1E-52 T 28-03-2018 CU254_RS34670 da8e2f18cfaaa254ab89d6b1434a56b0 247 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 95 115 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CU254_RS34670 da8e2f18cfaaa254ab89d6b1434a56b0 247 SUPERFAMILY SSF52096 2 245 4.25E-71 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS34670 da8e2f18cfaaa254ab89d6b1434a56b0 247 Gene3D G3DSA:3.90.226.10 1 247 6.0E-70 T 28-03-2018 CU254_RS34670 da8e2f18cfaaa254ab89d6b1434a56b0 247 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 244 2.4E-52 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CU254_RS27605 9ce4122d8bc337f7e4a4e665f51aa113 140 Pfam PF03995 Peptidase inhibitor family I36 46 115 3.0E-10 T 28-03-2018 CU254_RS04470 1d0379fbae273b623898f25c36235658 447 SMART SM01230 106 357 5.7E-127 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CU254_RS04470 1d0379fbae273b623898f25c36235658 447 Gene3D G3DSA:3.10.20.70 1 105 3.4E-32 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CU254_RS04470 1d0379fbae273b623898f25c36235658 447 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 8 442 5.8E-137 T 28-03-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CU254_RS04470 1d0379fbae273b623898f25c36235658 447 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 100 1.2E-25 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CU254_RS04470 1d0379fbae273b623898f25c36235658 447 Pfam PF00120 Glutamine synthetase, catalytic domain 107 441 1.0E-128 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CU254_RS04470 1d0379fbae273b623898f25c36235658 447 SUPERFAMILY SSF54368 8 104 2.22E-28 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CU254_RS04470 1d0379fbae273b623898f25c36235658 447 SUPERFAMILY SSF55931 108 444 1.18E-118 T 28-03-2018 CU254_RS04470 1d0379fbae273b623898f25c36235658 447 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 234 249 - T 28-03-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 CU254_RS04470 1d0379fbae273b623898f25c36235658 447 Gene3D G3DSA:3.30.590.10 106 447 4.4E-121 T 28-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CU254_RS00660 92a967d65927b0e0105d05544a439fa0 266 PRINTS PR01543 Arylamine N-acetyltransferase signature 27 50 2.1E-5 T 28-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 CU254_RS00660 92a967d65927b0e0105d05544a439fa0 266 PRINTS PR01543 Arylamine N-acetyltransferase signature 104 129 2.1E-5 T 28-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 CU254_RS00660 92a967d65927b0e0105d05544a439fa0 266 SUPERFAMILY SSF54001 7 241 2.75E-62 T 28-03-2018 CU254_RS00660 92a967d65927b0e0105d05544a439fa0 266 Pfam PF00797 N-acetyltransferase 30 248 1.9E-48 T 28-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 CU254_RS00660 92a967d65927b0e0105d05544a439fa0 266 Gene3D G3DSA:3.30.2140.10 6 147 7.6E-37 T 28-03-2018 CU254_RS00660 92a967d65927b0e0105d05544a439fa0 266 Gene3D G3DSA:3.30.2140.10 156 266 5.3E-13 T 28-03-2018 CU254_RS35485 1ea8e8492b325b87792c80b3fb7a7ef0 277 Pfam PF08543 Phosphomethylpyrimidine kinase 17 266 7.2E-80 T 28-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 CU254_RS35485 1ea8e8492b325b87792c80b3fb7a7ef0 277 Gene3D G3DSA:3.40.1190.20 4 272 1.0E-61 T 28-03-2018 IPR029056 Ribokinase-like CU254_RS35485 1ea8e8492b325b87792c80b3fb7a7ef0 277 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 10 268 1.6E-80 T 28-03-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CU254_RS35485 1ea8e8492b325b87792c80b3fb7a7ef0 277 SUPERFAMILY SSF53613 8 272 3.27E-75 T 28-03-2018 IPR029056 Ribokinase-like CU254_RS39600 933afab3d7610dde5cf95c4c94962b56 245 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 69 2.2E-20 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS39600 933afab3d7610dde5cf95c4c94962b56 245 SUPERFAMILY SSF48008 99 228 2.88E-19 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS39600 933afab3d7610dde5cf95c4c94962b56 245 SMART SM00345 15 76 2.5E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS39600 933afab3d7610dde5cf95c4c94962b56 245 SUPERFAMILY SSF46785 5 84 7.87E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS39600 933afab3d7610dde5cf95c4c94962b56 245 Gene3D G3DSA:1.20.120.530 95 236 5.3E-19 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS39600 933afab3d7610dde5cf95c4c94962b56 245 Gene3D G3DSA:1.10.10.10 1 73 2.2E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS39600 933afab3d7610dde5cf95c4c94962b56 245 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 3.8E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS39600 933afab3d7610dde5cf95c4c94962b56 245 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 3.8E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS39600 933afab3d7610dde5cf95c4c94962b56 245 Pfam PF07729 FCD domain 101 222 8.8E-17 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS39600 933afab3d7610dde5cf95c4c94962b56 245 SMART SM00895 101 226 6.4E-14 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS18210 235a505a6648734d7e8c1c8ffb85228d 307 Pfam PF00248 Aldo/keto reductase family 33 287 4.6E-20 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS18210 235a505a6648734d7e8c1c8ffb85228d 307 SUPERFAMILY SSF51430 33 294 9.3E-33 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS18210 235a505a6648734d7e8c1c8ffb85228d 307 Gene3D G3DSA:3.20.20.100 1 306 1.8E-33 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS39365 96a85dfa480a18375ebb0b70b73c42d8 147 SMART SM00342 31 114 1.1E-32 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS39365 96a85dfa480a18375ebb0b70b73c42d8 147 Pfam PF12833 Helix-turn-helix domain 37 115 9.3E-24 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS39365 96a85dfa480a18375ebb0b70b73c42d8 147 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 68 110 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CU254_RS39365 96a85dfa480a18375ebb0b70b73c42d8 147 Gene3D G3DSA:1.10.10.60 69 126 4.0E-15 T 28-03-2018 CU254_RS39365 96a85dfa480a18375ebb0b70b73c42d8 147 SUPERFAMILY SSF46689 15 65 5.2E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS39365 96a85dfa480a18375ebb0b70b73c42d8 147 Gene3D G3DSA:1.10.10.60 11 68 2.6E-14 T 28-03-2018 CU254_RS39365 96a85dfa480a18375ebb0b70b73c42d8 147 SUPERFAMILY SSF46689 67 116 1.21E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS29245 47bd6442867e5e1b4aeaa7c3c33c03af 383 Gene3D G3DSA:1.10.10.60 298 355 3.8E-8 T 28-03-2018 CU254_RS29245 47bd6442867e5e1b4aeaa7c3c33c03af 383 Pfam PF13556 PucR C-terminal helix-turn-helix domain 318 376 1.3E-18 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CU254_RS42090 6600d8fa9c656abef78de8e2fc11b436 427 SUPERFAMILY SSF89796 1 395 6.8E-119 T 28-03-2018 IPR023606 CoA-transferase family III domain CU254_RS42090 6600d8fa9c656abef78de8e2fc11b436 427 Gene3D G3DSA:3.40.50.10540 1 401 1.4E-124 T 28-03-2018 IPR023606 CoA-transferase family III domain CU254_RS42090 6600d8fa9c656abef78de8e2fc11b436 427 Pfam PF02515 CoA-transferase family III 4 372 2.7E-118 T 28-03-2018 IPR003673 CoA-transferase family III GO:0003824 CU254_RS28695 f8fda90f104ea2eb1b36cdb8c995eddd 272 Pfam PF13845 Septum formation 50 210 1.6E-14 T 28-03-2018 IPR026004 Septum formation-related domain CU254_RS09820 3fd4358cb3054329a0f408ef530310c9 192 SUPERFAMILY SSF109854 12 130 2.59E-16 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CU254_RS09820 3fd4358cb3054329a0f408ef530310c9 192 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 15 126 1.2E-16 T 28-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CU254_RS09820 3fd4358cb3054329a0f408ef530310c9 192 Gene3D G3DSA:1.20.120.450 5 132 2.2E-18 T 28-03-2018 CU254_RS09820 3fd4358cb3054329a0f408ef530310c9 192 TIGRFAM TIGR03086 TIGR03086: TIGR03086 family protein 10 185 1.3E-39 T 28-03-2018 IPR017520 Conserved hypothetical protein CHP03086 CU254_RS09820 3fd4358cb3054329a0f408ef530310c9 192 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 8 185 2.0E-25 T 28-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CU254_RS39310 d51c41bd38ef5ab2fd7f4abc10c6b50e 354 SUPERFAMILY SSF48403 45 172 8.93E-20 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain CU254_RS39310 d51c41bd38ef5ab2fd7f4abc10c6b50e 354 Pfam PF12796 Ankyrin repeats (3 copies) 52 133 2.6E-8 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain CU254_RS39310 d51c41bd38ef5ab2fd7f4abc10c6b50e 354 Gene3D G3DSA:1.25.40.20 118 181 5.5E-6 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain CU254_RS39310 d51c41bd38ef5ab2fd7f4abc10c6b50e 354 Gene3D G3DSA:1.25.40.20 47 117 9.0E-14 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain CU254_RS39310 d51c41bd38ef5ab2fd7f4abc10c6b50e 354 SMART SM00248 103 132 0.075 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 CU254_RS39310 d51c41bd38ef5ab2fd7f4abc10c6b50e 354 SMART SM00248 70 99 290.0 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 CU254_RS39310 d51c41bd38ef5ab2fd7f4abc10c6b50e 354 SMART SM00248 138 174 1200.0 T 28-03-2018 IPR002110 Ankyrin repeat GO:0005515 CU254_RS17240 60cdf9a9c235e46b1f7f773298abd8ae 162 Pfam PF01638 HxlR-like helix-turn-helix 30 117 8.3E-15 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type CU254_RS17240 60cdf9a9c235e46b1f7f773298abd8ae 162 Gene3D G3DSA:1.10.10.10 12 162 6.8E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS17240 60cdf9a9c235e46b1f7f773298abd8ae 162 SUPERFAMILY SSF46785 19 131 3.91E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS07500 d8024c610d3b402adce68a6c82ec2db6 110 SUPERFAMILY SSF54909 9 106 3.4E-19 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS07500 d8024c610d3b402adce68a6c82ec2db6 110 Pfam PF05336 L-rhamnose mutarotase 10 93 3.7E-15 T 28-03-2018 IPR008000 Rhamnose/fucose mutarotase GO:0005737|GO:0016857 CU254_RS03505 6012435bfde21ecef66947be1b3261ea 361 Gene3D G3DSA:3.40.50.2000 7 196 5.2E-5 T 28-03-2018 CU254_RS03505 6012435bfde21ecef66947be1b3261ea 361 Gene3D G3DSA:3.40.50.2000 197 332 2.3E-31 T 28-03-2018 CU254_RS03505 6012435bfde21ecef66947be1b3261ea 361 Pfam PF13579 Glycosyl transferase 4-like domain 20 176 7.3E-11 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CU254_RS03505 6012435bfde21ecef66947be1b3261ea 361 SUPERFAMILY SSF53756 18 358 1.94E-55 T 28-03-2018 CU254_RS03505 6012435bfde21ecef66947be1b3261ea 361 Pfam PF13692 Glycosyl transferases group 1 200 325 8.0E-20 T 28-03-2018 CU254_RS40765 d278361a7747b9dc671e7e564d976748 134 SUPERFAMILY SSF55874 37 128 5.52E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS40765 d278361a7747b9dc671e7e564d976748 134 Pfam PF13581 Histidine kinase-like ATPase domain 25 128 2.0E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS40765 d278361a7747b9dc671e7e564d976748 134 Gene3D G3DSA:3.30.565.10 8 134 9.4E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS05185 e70fb4395aa0daebe774b1aecf186cb1 747 Gene3D G3DSA:1.10.600.10 1 339 1.5E-79 T 28-03-2018 IPR008949 Isoprenoid synthase domain CU254_RS05185 e70fb4395aa0daebe774b1aecf186cb1 747 Gene3D G3DSA:1.10.600.10 388 730 2.6E-71 T 28-03-2018 IPR008949 Isoprenoid synthase domain CU254_RS05185 e70fb4395aa0daebe774b1aecf186cb1 747 SUPERFAMILY SSF48576 382 704 1.61E-54 T 28-03-2018 IPR008949 Isoprenoid synthase domain CU254_RS05185 e70fb4395aa0daebe774b1aecf186cb1 747 SUPERFAMILY SSF48576 2 334 4.03E-65 T 28-03-2018 IPR008949 Isoprenoid synthase domain CU254_RS25600 9824dac1c782f130357746738749bef4 299 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 15 102 1.6E-23 T 28-03-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CU254_RS25600 9824dac1c782f130357746738749bef4 299 SUPERFAMILY SSF51735 115 286 3.51E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS25600 9824dac1c782f130357746738749bef4 299 Gene3D G3DSA:3.40.50.10860 11 126 5.9E-38 T 28-03-2018 CU254_RS25600 9824dac1c782f130357746738749bef4 299 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 10 286 27.424 T 28-03-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CU254_RS25600 9824dac1c782f130357746738749bef4 299 Gene3D G3DSA:3.40.50.720 127 289 8.8E-31 T 28-03-2018 CU254_RS25600 9824dac1c782f130357746738749bef4 299 SUPERFAMILY SSF53223 11 114 2.36E-26 T 28-03-2018 CU254_RS40600 f4d20771ab2959d2246647d0570b26ad 134 Gene3D G3DSA:3.10.180.10 1 134 1.5E-21 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS40600 f4d20771ab2959d2246647d0570b26ad 134 SUPERFAMILY SSF54593 6 134 1.65E-12 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS03660 b1b1664c3dc11ab7734bae529da17d59 181 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 4 175 4.6E-62 T 28-03-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG CU254_RS03660 b1b1664c3dc11ab7734bae529da17d59 181 Gene3D G3DSA:3.40.50.450 2 180 3.6E-65 T 28-03-2018 CU254_RS03660 b1b1664c3dc11ab7734bae529da17d59 181 SUPERFAMILY SSF102405 2 177 2.75E-63 T 28-03-2018 CU254_RS03660 b1b1664c3dc11ab7734bae529da17d59 181 Pfam PF03641 Possible lysine decarboxylase 46 175 3.3E-44 T 28-03-2018 IPR031100 LOG family CU254_RS28475 376aa26e719659769dc1bd1583e00eed 240 Pfam PF02654 Cobalamin-5-phosphate synthase 2 237 9.4E-35 T 28-03-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CU254_RS28475 376aa26e719659769dc1bd1583e00eed 240 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 240 36.056 T 28-03-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CU254_RS31045 7b8a8a1aa5f5b1c3cf8028b8508ae22b 134 Gene3D G3DSA:3.30.300.20 1 134 3.3E-22 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CU254_RS31045 7b8a8a1aa5f5b1c3cf8028b8508ae22b 134 SUPERFAMILY SSF82784 1 131 3.4E-23 T 28-03-2018 IPR003718 OsmC/Ohr family CU254_RS31045 7b8a8a1aa5f5b1c3cf8028b8508ae22b 134 Pfam PF02566 OsmC-like protein 30 128 2.3E-16 T 28-03-2018 IPR003718 OsmC/Ohr family CU254_RS11460 f022d1949cca14741503c14577ee5a69 162 Pfam PF01381 Helix-turn-helix 13 68 1.8E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS11460 f022d1949cca14741503c14577ee5a69 162 Gene3D G3DSA:1.10.260.40 1 70 9.6E-11 T 28-03-2018 CU254_RS11460 f022d1949cca14741503c14577ee5a69 162 SUPERFAMILY SSF47413 4 71 1.38E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS11460 f022d1949cca14741503c14577ee5a69 162 SMART SM00530 11 68 1.3E-5 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS12225 728d2a0af77c0cea7ed25ca9383c1568 246 Gene3D G3DSA:3.40.50.720 1 38 4.1E-7 T 28-03-2018 CU254_RS12225 728d2a0af77c0cea7ed25ca9383c1568 246 Gene3D G3DSA:3.40.50.720 39 246 1.3E-60 T 28-03-2018 CU254_RS12225 728d2a0af77c0cea7ed25ca9383c1568 246 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 184 0.0016 T 28-03-2018 CU254_RS12225 728d2a0af77c0cea7ed25ca9383c1568 246 SUPERFAMILY SSF51735 2 244 1.97E-73 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS12225 728d2a0af77c0cea7ed25ca9383c1568 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 243 3.6E-61 T 28-03-2018 CU254_RS12225 728d2a0af77c0cea7ed25ca9383c1568 246 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS12225 728d2a0af77c0cea7ed25ca9383c1568 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 7.6E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS12225 728d2a0af77c0cea7ed25ca9383c1568 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 7.6E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS12225 728d2a0af77c0cea7ed25ca9383c1568 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 7.6E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS12225 728d2a0af77c0cea7ed25ca9383c1568 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.0E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS12225 728d2a0af77c0cea7ed25ca9383c1568 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.0E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS12225 728d2a0af77c0cea7ed25ca9383c1568 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 1.0E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS12225 728d2a0af77c0cea7ed25ca9383c1568 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 1.0E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS12225 728d2a0af77c0cea7ed25ca9383c1568 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 1.0E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS12225 728d2a0af77c0cea7ed25ca9383c1568 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.0E-32 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS07315 fb044e88f624f15d8fcbcd77f2f4aa1b 239 SUPERFAMILY SSF53933 52 141 1.05E-31 T 28-03-2018 IPR016191 Ribonuclease/ribotoxin GO:0003723|GO:0004540 CU254_RS07315 fb044e88f624f15d8fcbcd77f2f4aa1b 239 Pfam PF00545 ribonuclease 183 233 4.2E-8 T 28-03-2018 IPR000026 Guanine-specific ribonuclease N1/T1/U2 GO:0003723|GO:0004521 CU254_RS07315 fb044e88f624f15d8fcbcd77f2f4aa1b 239 Pfam PF00545 ribonuclease 60 139 2.7E-26 T 28-03-2018 IPR000026 Guanine-specific ribonuclease N1/T1/U2 GO:0003723|GO:0004521 CU254_RS07315 fb044e88f624f15d8fcbcd77f2f4aa1b 239 Gene3D G3DSA:3.10.450.30 149 236 2.8E-14 T 28-03-2018 CU254_RS07315 fb044e88f624f15d8fcbcd77f2f4aa1b 239 SUPERFAMILY SSF53933 149 235 3.97E-15 T 28-03-2018 IPR016191 Ribonuclease/ribotoxin GO:0003723|GO:0004540 CU254_RS07315 fb044e88f624f15d8fcbcd77f2f4aa1b 239 Gene3D G3DSA:3.10.450.30 50 145 3.4E-32 T 28-03-2018 CU254_RS14355 a2d6828a5b2a183114684327b4f58dfc 390 Gene3D G3DSA:3.20.20.70 3 296 6.4E-44 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS14355 a2d6828a5b2a183114684327b4f58dfc 390 TIGRFAM TIGR03962 mycofact_rSAM: mycofactocin radical SAM maturase 5 342 7.9E-201 T 28-03-2018 IPR023913 Mycofactocin, radical SAM peptide maturase CU254_RS14355 a2d6828a5b2a183114684327b4f58dfc 390 SUPERFAMILY SSF102114 14 317 5.89E-62 T 28-03-2018 CU254_RS14355 a2d6828a5b2a183114684327b4f58dfc 390 PIRSF PIRSF037420 241 351 1.7E-9 T 28-03-2018 CU254_RS14355 a2d6828a5b2a183114684327b4f58dfc 390 PIRSF PIRSF037420 4 230 4.4E-52 T 28-03-2018 CU254_RS14355 a2d6828a5b2a183114684327b4f58dfc 390 Pfam PF13353 4Fe-4S single cluster domain 22 124 5.0E-5 T 28-03-2018 CU254_RS14355 a2d6828a5b2a183114684327b4f58dfc 390 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 245 325 2.3E-13 T 28-03-2018 IPR023885 4Fe4S-binding SPASM domain CU254_RS14355 a2d6828a5b2a183114684327b4f58dfc 390 Pfam PF04055 Radical SAM superfamily 21 171 6.2E-24 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CU254_RS14355 a2d6828a5b2a183114684327b4f58dfc 390 SMART SM00729 15 214 0.0041 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CU254_RS32420 c62245b5cce4d070c93655ae4f45d6c5 254 SMART SM00967 15 92 7.8E-9 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CU254_RS32420 c62245b5cce4d070c93655ae4f45d6c5 254 Gene3D G3DSA:3.40.1280.10 87 253 6.7E-39 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CU254_RS32420 c62245b5cce4d070c93655ae4f45d6c5 254 SUPERFAMILY SSF75217 95 251 3.07E-37 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CU254_RS32420 c62245b5cce4d070c93655ae4f45d6c5 254 Pfam PF00588 SpoU rRNA Methylase family 107 244 3.9E-31 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CU254_RS32420 c62245b5cce4d070c93655ae4f45d6c5 254 SUPERFAMILY SSF55315 10 86 1.53E-9 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CU254_RS32420 c62245b5cce4d070c93655ae4f45d6c5 254 Gene3D G3DSA:3.30.1330.30 7 86 3.3E-12 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CU254_RS32420 c62245b5cce4d070c93655ae4f45d6c5 254 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 16 90 7.8E-12 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CU254_RS31355 eb6ea95561ae122b6cf15a36de5cd8a7 356 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 2 355 36.836 T 28-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 CU254_RS31355 eb6ea95561ae122b6cf15a36de5cd8a7 356 Pfam PF03462 PCRF domain 11 202 4.8E-65 T 28-03-2018 IPR005139 Peptide chain release factor GO:0006415 CU254_RS31355 eb6ea95561ae122b6cf15a36de5cd8a7 356 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 5 353 1.9E-147 T 28-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 CU254_RS31355 eb6ea95561ae122b6cf15a36de5cd8a7 356 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 226 242 - T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CU254_RS31355 eb6ea95561ae122b6cf15a36de5cd8a7 356 SMART SM00937 64 177 2.0E-49 T 28-03-2018 IPR005139 Peptide chain release factor GO:0006415 CU254_RS31355 eb6ea95561ae122b6cf15a36de5cd8a7 356 Pfam PF00472 RF-1 domain 210 319 6.8E-40 T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CU254_RS31355 eb6ea95561ae122b6cf15a36de5cd8a7 356 SUPERFAMILY SSF75620 9 351 1.14E-125 T 28-03-2018 CU254_RS31355 eb6ea95561ae122b6cf15a36de5cd8a7 356 Gene3D G3DSA:3.30.160.20 208 314 6.7E-33 T 28-03-2018 CU254_RS31355 eb6ea95561ae122b6cf15a36de5cd8a7 356 Gene3D G3DSA:1.20.58.410 2 95 3.8E-20 T 28-03-2018 CU254_RS39660 b2276089aa031e2a5c26951f0ee337ca 356 SUPERFAMILY SSF51621 220 288 1.07E-51 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CU254_RS39660 b2276089aa031e2a5c26951f0ee337ca 356 SUPERFAMILY SSF51621 24 193 1.07E-51 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CU254_RS39660 b2276089aa031e2a5c26951f0ee337ca 356 Gene3D G3DSA:3.20.20.360 15 316 3.8E-53 T 28-03-2018 CU254_RS39660 b2276089aa031e2a5c26951f0ee337ca 356 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 32 195 2.0E-29 T 28-03-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 CU254_RS39660 b2276089aa031e2a5c26951f0ee337ca 356 PIRSF PIRSF015582 14 348 2.2E-81 T 28-03-2018 IPR011206 Citrate lyase beta subunit-like CU254_RS00325 c1ef06ff1e47a6d50dd43996c5c3736d 533 SUPERFAMILY SSF53474 40 519 1.05E-100 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS00325 c1ef06ff1e47a6d50dd43996c5c3736d 533 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 202 217 - T 28-03-2018 IPR019826 Carboxylesterase type B, active site CU254_RS00325 c1ef06ff1e47a6d50dd43996c5c3736d 533 Gene3D G3DSA:3.40.50.1820 15 533 7.9E-114 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS00325 c1ef06ff1e47a6d50dd43996c5c3736d 533 Pfam PF00135 Carboxylesterase family 51 507 1.7E-96 T 28-03-2018 IPR002018 Carboxylesterase, type B CU254_RS01995 d6fda7f208b475131fa261933a354b0b 92 PRINTS PR00973 Ribosomal protein S17 family signature 65 75 9.0E-12 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS01995 d6fda7f208b475131fa261933a354b0b 92 PRINTS PR00973 Ribosomal protein S17 family signature 75 82 9.0E-12 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS01995 d6fda7f208b475131fa261933a354b0b 92 PRINTS PR00973 Ribosomal protein S17 family signature 33 56 9.0E-12 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS01995 d6fda7f208b475131fa261933a354b0b 92 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 14 89 23.967 T 28-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS01995 d6fda7f208b475131fa261933a354b0b 92 ProSitePatterns PS00056 Ribosomal protein S17 signature. 65 77 - T 28-03-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS01995 d6fda7f208b475131fa261933a354b0b 92 SUPERFAMILY SSF50249 14 91 3.56E-29 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CU254_RS01995 d6fda7f208b475131fa261933a354b0b 92 Pfam PF00366 Ribosomal protein S17 19 85 5.6E-30 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS01995 d6fda7f208b475131fa261933a354b0b 92 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 14 85 7.0E-23 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS01995 d6fda7f208b475131fa261933a354b0b 92 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 14 85 3.4E-33 T 28-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS01995 d6fda7f208b475131fa261933a354b0b 92 Gene3D G3DSA:2.40.50.140 14 91 1.8E-28 T 28-03-2018 CU254_RS01365 0f6b1974b838564a12614c04dda367d7 427 SUPERFAMILY SSF140490 326 417 2.09E-35 T 28-03-2018 CU254_RS01365 0f6b1974b838564a12614c04dda367d7 427 SUPERFAMILY SSF142984 241 323 3.4E-23 T 28-03-2018 CU254_RS01365 0f6b1974b838564a12614c04dda367d7 427 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 332 412 6.5E-33 T 28-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS01365 0f6b1974b838564a12614c04dda367d7 427 SUPERFAMILY SSF142019 7 239 6.93E-86 T 28-03-2018 CU254_RS01365 0f6b1974b838564a12614c04dda367d7 427 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 167 182 - T 28-03-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS01365 0f6b1974b838564a12614c04dda367d7 427 Gene3D G3DSA:3.10.560.10 232 306 1.5E-6 T 28-03-2018 CU254_RS01365 0f6b1974b838564a12614c04dda367d7 427 Pfam PF10531 SLBB domain 243 290 2.8E-10 T 28-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS01365 0f6b1974b838564a12614c04dda367d7 427 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 341 352 - T 28-03-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS01365 0f6b1974b838564a12614c04dda367d7 427 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 48 217 8.2E-48 T 28-03-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS01365 0f6b1974b838564a12614c04dda367d7 427 SMART SM00928 328 373 2.1E-24 T 28-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS01365 0f6b1974b838564a12614c04dda367d7 427 TIGRFAM TIGR01959 nuoF_fam: NADH oxidoreductase (quinone), F subunit 9 412 3.5E-188 T 28-03-2018 IPR011537 NADH ubiquinone oxidoreductase, F subunit GO:0010181|GO:0016651|GO:0051287|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS17050 b0cd63926f4eb5500101868162c72a3e 273 SUPERFAMILY SSF53474 23 267 3.3E-43 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS17050 b0cd63926f4eb5500101868162c72a3e 273 Pfam PF12697 Alpha/beta hydrolase family 31 259 1.9E-18 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS17050 b0cd63926f4eb5500101868162c72a3e 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 96 109 1.5E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS17050 b0cd63926f4eb5500101868162c72a3e 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 212 226 1.5E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS17050 b0cd63926f4eb5500101868162c72a3e 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 110 123 1.5E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS17050 b0cd63926f4eb5500101868162c72a3e 273 PRINTS PR00111 Alpha/beta hydrolase fold signature 52 67 1.5E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS17050 b0cd63926f4eb5500101868162c72a3e 273 PRINTS PR00412 Epoxide hydrolase signature 210 226 7.5E-5 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS17050 b0cd63926f4eb5500101868162c72a3e 273 PRINTS PR00412 Epoxide hydrolase signature 52 67 7.5E-5 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS17050 b0cd63926f4eb5500101868162c72a3e 273 PRINTS PR00412 Epoxide hydrolase signature 242 264 7.5E-5 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS17050 b0cd63926f4eb5500101868162c72a3e 273 Gene3D G3DSA:3.40.50.1820 7 272 5.9E-40 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS32690 33bda89525e226ce60dea4126428f36f 362 Gene3D G3DSA:2.50.20.10 41 256 9.3E-37 T 28-03-2018 CU254_RS32690 33bda89525e226ce60dea4126428f36f 362 SUPERFAMILY SSF89392 101 254 6.67E-14 T 28-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX CU254_RS29320 f46386eb61edf7118e58d02073aaa031 132 SUPERFAMILY SSF54593 3 120 3.62E-23 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS29320 f46386eb61edf7118e58d02073aaa031 132 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 117 3.1E-9 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CU254_RS29320 f46386eb61edf7118e58d02073aaa031 132 Gene3D G3DSA:3.10.180.10 1 131 2.1E-21 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS16035 d6189bd5f8c222289a6b7095d1145bbc 231 SMART SM00020 28 225 2.2E-25 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CU254_RS16035 d6189bd5f8c222289a6b7095d1145bbc 231 Gene3D G3DSA:2.40.10.10 29 56 5.1E-10 T 28-03-2018 CU254_RS16035 d6189bd5f8c222289a6b7095d1145bbc 231 SUPERFAMILY SSF50494 4 230 6.85E-36 T 28-03-2018 IPR009003 Peptidase S1, PA clan CU254_RS16035 d6189bd5f8c222289a6b7095d1145bbc 231 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 92 106 5.6E-12 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CU254_RS16035 d6189bd5f8c222289a6b7095d1145bbc 231 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 174 186 5.6E-12 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CU254_RS16035 d6189bd5f8c222289a6b7095d1145bbc 231 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 50 65 5.6E-12 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CU254_RS16035 d6189bd5f8c222289a6b7095d1145bbc 231 Gene3D G3DSA:2.40.10.10 105 231 4.7E-22 T 28-03-2018 CU254_RS16035 d6189bd5f8c222289a6b7095d1145bbc 231 Pfam PF00089 Trypsin 29 225 1.8E-29 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CU254_RS16035 d6189bd5f8c222289a6b7095d1145bbc 231 Gene3D G3DSA:2.40.10.10 57 104 9.9E-10 T 28-03-2018 CU254_RS36040 5040c71cd9ee4160096dcd6138b3a4ee 151 TIGRFAM TIGR02133 RPI_actino: ribose 5-phosphate isomerase 1 149 1.0E-52 T 28-03-2018 IPR011860 Ribose 5-phosphate isomerase GO:0004751 CU254_RS36040 5040c71cd9ee4160096dcd6138b3a4ee 151 SUPERFAMILY SSF89623 1 150 2.88E-46 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CU254_RS36040 5040c71cd9ee4160096dcd6138b3a4ee 151 PIRSF PIRSF005384 1 151 2.5E-44 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CU254_RS36040 5040c71cd9ee4160096dcd6138b3a4ee 151 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 149 2.2E-35 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CU254_RS36040 5040c71cd9ee4160096dcd6138b3a4ee 151 Gene3D G3DSA:3.40.1400.10 1 151 8.2E-53 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CU254_RS36040 5040c71cd9ee4160096dcd6138b3a4ee 151 Pfam PF02502 Ribose/Galactose Isomerase 3 144 1.8E-42 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CU254_RS29755 a944146eec546ff2270a1340329b2a82 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 22 33 3.8E-11 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS29755 a944146eec546ff2270a1340329b2a82 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 6 22 3.8E-11 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS29755 a944146eec546ff2270a1340329b2a82 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 33 52 3.8E-11 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS29755 a944146eec546ff2270a1340329b2a82 152 SUPERFAMILY SSF46785 5 66 1.1E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS29755 a944146eec546ff2270a1340329b2a82 152 SUPERFAMILY SSF54909 66 146 1.88E-12 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS29755 a944146eec546ff2270a1340329b2a82 152 Gene3D G3DSA:1.10.10.10 6 57 2.3E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS29755 a944146eec546ff2270a1340329b2a82 152 Pfam PF13412 Winged helix-turn-helix DNA-binding 6 53 3.6E-14 T 28-03-2018 CU254_RS29755 a944146eec546ff2270a1340329b2a82 152 Gene3D G3DSA:3.30.70.920 58 146 1.4E-16 T 28-03-2018 CU254_RS29755 a944146eec546ff2270a1340329b2a82 152 Pfam PF01037 Lrp/AsnC ligand binding domain 83 142 9.4E-11 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CU254_RS29755 a944146eec546ff2270a1340329b2a82 152 SMART SM00344 6 113 4.9E-28 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CU254_RS35365 d3467adb5106ca8b6ca25e7b5f432557 283 Pfam PF01904 Protein of unknown function DUF72 24 271 3.3E-66 T 28-03-2018 IPR002763 Protein of unknown function DUF72 CU254_RS35365 d3467adb5106ca8b6ca25e7b5f432557 283 SUPERFAMILY SSF117396 6 135 9.81E-78 T 28-03-2018 IPR002763 Protein of unknown function DUF72 CU254_RS35365 d3467adb5106ca8b6ca25e7b5f432557 283 SUPERFAMILY SSF117396 163 274 9.81E-78 T 28-03-2018 IPR002763 Protein of unknown function DUF72 CU254_RS35365 d3467adb5106ca8b6ca25e7b5f432557 283 Gene3D G3DSA:3.20.20.410 2 283 8.9E-89 T 28-03-2018 IPR002763 Protein of unknown function DUF72 CU254_RS14175 f2e8d8a46327f4be0d4dd4f3e6de6fee 241 Gene3D G3DSA:3.40.50.2300 109 219 4.2E-4 T 28-03-2018 CU254_RS14175 f2e8d8a46327f4be0d4dd4f3e6de6fee 241 PIRSF PIRSF015736 1 241 1.1E-43 T 28-03-2018 IPR026286 Maleate isomerase/Arylmalonate decarboxylase CU254_RS32505 954da8de2d7ca378c933e950f414b495 154 Pfam PF04073 Aminoacyl-tRNA editing domain 26 143 2.1E-32 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CU254_RS32505 954da8de2d7ca378c933e950f414b495 154 SUPERFAMILY SSF55826 5 149 1.02E-37 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CU254_RS32505 954da8de2d7ca378c933e950f414b495 154 Gene3D G3DSA:3.90.960.10 1 153 8.2E-41 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CU254_RS29195 fa52c5d86ee01641bebd747bf7fa0453 125 Pfam PF00355 Rieske [2Fe-2S] domain 10 100 1.6E-8 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CU254_RS29195 fa52c5d86ee01641bebd747bf7fa0453 125 SUPERFAMILY SSF50022 8 125 4.71E-21 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CU254_RS29195 fa52c5d86ee01641bebd747bf7fa0453 125 Gene3D G3DSA:2.102.10.10 3 125 3.4E-22 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CU254_RS04715 022a8b121f8ea7a4feb02042b254d198 145 Gene3D G3DSA:3.10.180.10 5 141 1.0E-12 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS04715 022a8b121f8ea7a4feb02042b254d198 145 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 95 3.5E-8 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CU254_RS04715 022a8b121f8ea7a4feb02042b254d198 145 SUPERFAMILY SSF54593 5 119 2.89E-15 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS01470 9cb9a95cb459a5d891e9f26c3154394d 210 Pfam PF01522 Polysaccharide deacetylase 42 161 2.8E-18 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CU254_RS01470 9cb9a95cb459a5d891e9f26c3154394d 210 Gene3D G3DSA:3.20.20.370 26 199 6.0E-20 T 28-03-2018 CU254_RS01470 9cb9a95cb459a5d891e9f26c3154394d 210 SUPERFAMILY SSF88713 44 168 1.11E-20 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CU254_RS27130 b3f981011e8d4b9c05cab8d173a9ef88 280 SUPERFAMILY SSF51735 2 243 2.56E-51 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS27130 b3f981011e8d4b9c05cab8d173a9ef88 280 Pfam PF13460 NAD(P)H-binding 6 179 5.6E-25 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS27130 b3f981011e8d4b9c05cab8d173a9ef88 280 Gene3D G3DSA:3.40.50.720 2 280 1.4E-32 T 28-03-2018 CU254_RS26555 c00ca32f10a2ab7754371c1bb66ee907 410 Gene3D G3DSA:3.40.710.10 1 410 6.7E-94 T 28-03-2018 CU254_RS26555 c00ca32f10a2ab7754371c1bb66ee907 410 Pfam PF00144 Beta-lactamase 24 393 5.8E-68 T 28-03-2018 IPR001466 Beta-lactamase-related CU254_RS26555 c00ca32f10a2ab7754371c1bb66ee907 410 SUPERFAMILY SSF56601 19 405 9.05E-95 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CU254_RS33360 1367384e81d41b070ea346bb27abaf05 326 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 128 321 3.0E-32 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS33360 1367384e81d41b070ea346bb27abaf05 326 SUPERFAMILY SSF161098 106 308 5.01E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS33360 1367384e81d41b070ea346bb27abaf05 326 Gene3D G3DSA:1.10.3720.10 17 311 8.7E-35 T 28-03-2018 CU254_RS37660 1283c6072d3ce180a278c75da139749a 580 SUPERFAMILY SSF90123 15 322 1.57E-51 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CU254_RS37660 1283c6072d3ce180a278c75da139749a 580 Gene3D G3DSA:1.20.1560.10 8 322 3.2E-42 T 28-03-2018 CU254_RS37660 1283c6072d3ce180a278c75da139749a 580 SMART SM00382 365 555 1.3E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS37660 1283c6072d3ce180a278c75da139749a 580 Pfam PF00005 ABC transporter 356 509 4.7E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS37660 1283c6072d3ce180a278c75da139749a 580 SUPERFAMILY SSF52540 332 577 8.85E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS37660 1283c6072d3ce180a278c75da139749a 580 Pfam PF00664 ABC transporter transmembrane region 34 299 6.5E-26 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CU254_RS37660 1283c6072d3ce180a278c75da139749a 580 Gene3D G3DSA:3.40.50.300 324 580 1.4E-58 T 28-03-2018 CU254_RS07075 7eadf9ebe0b6346429853493920f8f64 124 SUPERFAMILY SSF54593 3 117 6.22E-14 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS07075 7eadf9ebe0b6346429853493920f8f64 124 Gene3D G3DSA:3.10.180.10 2 124 5.1E-22 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS06505 67fcb0442a05e66e9b7285128f2812df 259 SUPERFAMILY SSF52096 3 253 2.75E-81 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS06505 67fcb0442a05e66e9b7285128f2812df 259 Gene3D G3DSA:1.10.12.10 216 249 1.2E-12 T 28-03-2018 IPR014748 Crontonase, C-terminal CU254_RS06505 67fcb0442a05e66e9b7285128f2812df 259 Gene3D G3DSA:3.90.226.10 4 215 4.1E-72 T 28-03-2018 CU254_RS06505 67fcb0442a05e66e9b7285128f2812df 259 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 250 1.9E-66 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CU254_RS20225 550618d01f246fac6a26d29b4675b6c6 240 SMART SM00422 1 75 1.4E-16 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS20225 550618d01f246fac6a26d29b4675b6c6 240 Gene3D G3DSA:1.10.1660.10 110 233 0.0032 T 28-03-2018 CU254_RS20225 550618d01f246fac6a26d29b4675b6c6 240 Gene3D G3DSA:1.10.1660.10 1 97 4.5E-18 T 28-03-2018 CU254_RS20225 550618d01f246fac6a26d29b4675b6c6 240 Pfam PF00376 MerR family regulatory protein 12 43 1.7E-10 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS20225 550618d01f246fac6a26d29b4675b6c6 240 SUPERFAMILY SSF46955 16 83 2.01E-12 T 28-03-2018 IPR009061 Putative DNA-binding domain CU254_RS02380 c3b4a1496d59e068b1e6cbd5b069ad8b 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 3.2E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS02380 c3b4a1496d59e068b1e6cbd5b069ad8b 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 3.2E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS02380 c3b4a1496d59e068b1e6cbd5b069ad8b 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 3.2E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS02380 c3b4a1496d59e068b1e6cbd5b069ad8b 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 3.2E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS02380 c3b4a1496d59e068b1e6cbd5b069ad8b 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 3.2E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS02380 c3b4a1496d59e068b1e6cbd5b069ad8b 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 3.2E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS02380 c3b4a1496d59e068b1e6cbd5b069ad8b 246 Gene3D G3DSA:3.40.50.720 1 38 4.3E-10 T 28-03-2018 CU254_RS02380 c3b4a1496d59e068b1e6cbd5b069ad8b 246 Gene3D G3DSA:3.40.50.720 39 246 1.1E-57 T 28-03-2018 CU254_RS02380 c3b4a1496d59e068b1e6cbd5b069ad8b 246 SUPERFAMILY SSF51735 1 246 6.67E-74 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS02380 c3b4a1496d59e068b1e6cbd5b069ad8b 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 1.6E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS02380 c3b4a1496d59e068b1e6cbd5b069ad8b 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 1.6E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS02380 c3b4a1496d59e068b1e6cbd5b069ad8b 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.6E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS02380 c3b4a1496d59e068b1e6cbd5b069ad8b 246 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 210 0.0098 T 28-03-2018 CU254_RS02380 c3b4a1496d59e068b1e6cbd5b069ad8b 246 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS02380 c3b4a1496d59e068b1e6cbd5b069ad8b 246 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 245 1.1E-54 T 28-03-2018 CU254_RS14265 4f252f782e57e1f9faa9ce2162d6ddd4 531 Pfam PF13515 Fusaric acid resistance protein-like 302 426 1.4E-23 T 28-03-2018 CU254_RS17060 35c28e1b0f48ea475949c1e75917610b 381 SUPERFAMILY SSF55031 182 282 2.69E-18 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CU254_RS17060 35c28e1b0f48ea475949c1e75917610b 381 Pfam PF01546 Peptidase family M20/M25/M40 74 371 2.1E-37 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CU254_RS17060 35c28e1b0f48ea475949c1e75917610b 381 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 73 82 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CU254_RS17060 35c28e1b0f48ea475949c1e75917610b 381 Gene3D G3DSA:3.40.630.10 2 273 2.0E-66 T 28-03-2018 CU254_RS17060 35c28e1b0f48ea475949c1e75917610b 381 SUPERFAMILY SSF53187 297 374 1.51E-64 T 28-03-2018 CU254_RS17060 35c28e1b0f48ea475949c1e75917610b 381 SUPERFAMILY SSF53187 7 181 1.51E-64 T 28-03-2018 CU254_RS17060 35c28e1b0f48ea475949c1e75917610b 381 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 14 363 9.6E-78 T 28-03-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase CU254_RS17060 35c28e1b0f48ea475949c1e75917610b 381 Pfam PF07687 Peptidase dimerisation domain 178 281 3.7E-21 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CU254_RS17060 35c28e1b0f48ea475949c1e75917610b 381 Gene3D G3DSA:3.40.630.10 274 377 4.5E-10 T 28-03-2018 CU254_RS36380 b9c1510e1d9545f47aa73bba3002ec31 549 Gene3D G3DSA:1.20.1250.20 15 216 5.3E-32 T 28-03-2018 CU254_RS36380 b9c1510e1d9545f47aa73bba3002ec31 549 Gene3D G3DSA:1.20.1250.20 269 540 7.5E-32 T 28-03-2018 CU254_RS36380 b9c1510e1d9545f47aa73bba3002ec31 549 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 25 521 3.2E-74 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CU254_RS36380 b9c1510e1d9545f47aa73bba3002ec31 549 Pfam PF07690 Major Facilitator Superfamily 29 427 4.0E-49 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS36380 b9c1510e1d9545f47aa73bba3002ec31 549 SUPERFAMILY SSF103473 16 212 1.31E-63 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS36380 b9c1510e1d9545f47aa73bba3002ec31 549 SUPERFAMILY SSF103473 265 437 1.31E-63 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS36380 b9c1510e1d9545f47aa73bba3002ec31 549 SUPERFAMILY SSF103473 500 525 1.31E-63 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS24715 16a1e04895b617b5347cf870cc3a92b3 433 Gene3D G3DSA:3.90.1300.10 119 235 1.0E-7 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS24715 16a1e04895b617b5347cf870cc3a92b3 433 Gene3D G3DSA:3.90.1300.10 236 291 0.036 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS24715 16a1e04895b617b5347cf870cc3a92b3 433 Gene3D G3DSA:3.90.1300.10 16 74 0.11 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS24715 16a1e04895b617b5347cf870cc3a92b3 433 Gene3D G3DSA:3.10.490.10 300 427 1.0E-16 T 28-03-2018 CU254_RS24715 16a1e04895b617b5347cf870cc3a92b3 433 SUPERFAMILY SSF75304 17 291 3.92E-14 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS16530 bf1eb5d1fd8b5c4a6c0a9e369349f37e 168 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 4 167 1.1E-52 T 28-03-2018 IPR006286 Peptidase C56, PfpI CU254_RS16530 bf1eb5d1fd8b5c4a6c0a9e369349f37e 168 Pfam PF01965 DJ-1/PfpI family 3 165 1.5E-53 T 28-03-2018 IPR002818 DJ-1/PfpI CU254_RS16530 bf1eb5d1fd8b5c4a6c0a9e369349f37e 168 Gene3D G3DSA:3.40.50.880 1 168 4.9E-50 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS16530 bf1eb5d1fd8b5c4a6c0a9e369349f37e 168 SUPERFAMILY SSF52317 1 167 1.1E-49 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS04130 63e25e320abbc4d9a49a7b4821889541 379 Gene3D G3DSA:3.40.50.2300 51 322 4.2E-4 T 28-03-2018 CU254_RS04130 63e25e320abbc4d9a49a7b4821889541 379 Pfam PF14258 Domain of unknown function (DUF4350) 51 113 3.5E-7 T 28-03-2018 IPR025646 Domain of unknown function DUF4350 CU254_RS20060 541592c41d0907bc01c1d9163a1ff883 529 Gene3D G3DSA:3.30.300.30 424 528 4.5E-28 T 28-03-2018 CU254_RS20060 541592c41d0907bc01c1d9163a1ff883 529 ProSitePatterns PS00455 Putative AMP-binding domain signature. 182 193 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS20060 541592c41d0907bc01c1d9163a1ff883 529 Gene3D G3DSA:3.40.50.980 16 187 8.5E-41 T 28-03-2018 CU254_RS20060 541592c41d0907bc01c1d9163a1ff883 529 Pfam PF13193 AMP-binding enzyme C-terminal domain 438 513 9.5E-22 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS20060 541592c41d0907bc01c1d9163a1ff883 529 Gene3D G3DSA:3.40.50.980 188 340 1.4E-42 T 28-03-2018 CU254_RS20060 541592c41d0907bc01c1d9163a1ff883 529 Gene3D G3DSA:2.30.38.10 341 422 2.0E-26 T 28-03-2018 CU254_RS20060 541592c41d0907bc01c1d9163a1ff883 529 SUPERFAMILY SSF56801 14 525 1.83E-157 T 28-03-2018 CU254_RS20060 541592c41d0907bc01c1d9163a1ff883 529 Pfam PF00501 AMP-binding enzyme 26 429 8.1E-104 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS17055 ab95ead230fc28c3878f6ca565116507 312 Pfam PF06267 Family of unknown function (DUF1028) 2 196 6.5E-66 T 28-03-2018 IPR010430 Protein of unknown function DUF1028 CU254_RS17055 ab95ead230fc28c3878f6ca565116507 312 SUPERFAMILY SSF56235 2 204 3.4E-63 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CU254_RS17055 ab95ead230fc28c3878f6ca565116507 312 Gene3D G3DSA:3.60.20.10 1 207 1.1E-71 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CU254_RS15755 58162382f145f19e920739f90001b539 256 Gene3D G3DSA:3.40.50.1860 90 220 0.0046 T 28-03-2018 CU254_RS15755 58162382f145f19e920739f90001b539 256 PIRSF PIRSF015736 1 251 5.1E-57 T 28-03-2018 IPR026286 Maleate isomerase/Arylmalonate decarboxylase CU254_RS15755 58162382f145f19e920739f90001b539 256 Pfam PF01177 Asp/Glu/Hydantoin racemase 6 224 1.4E-7 T 28-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CU254_RS15755 58162382f145f19e920739f90001b539 256 Hamap MF_00943 Maleate isomerase [maiA]. 4 250 46.151 T 28-03-2018 IPR028615 Maleate isomerase GO:0050076 KEGG: 00650+5.2.1.1|KEGG: 00760+5.2.1.1|MetaCyc: PWY-5033|MetaCyc: PWY-6993|MetaCyc: PWY-7128|MetaCyc: PWY-722 CU254_RS30700 c28fb39abe12539cb970032e06c590c4 211 Pfam PF01810 LysE type translocator 13 207 1.1E-30 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CU254_RS30700 c28fb39abe12539cb970032e06c590c4 211 PIRSF PIRSF006324 1 209 9.1E-50 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CU254_RS22740 f3ae285a5a5a03867086f5b5db9412b1 322 Pfam PF03741 Integral membrane protein TerC family 69 273 2.0E-51 T 28-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 CU254_RS22740 f3ae285a5a5a03867086f5b5db9412b1 322 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 4 312 4.7E-116 T 28-03-2018 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 CU254_RS31525 5de3fcfd487499a6861db264b650a65f 155 Gene3D G3DSA:3.40.430.10 1 149 3.0E-49 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CU254_RS31525 5de3fcfd487499a6861db264b650a65f 155 SUPERFAMILY SSF53597 1 147 1.44E-49 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CU254_RS31525 5de3fcfd487499a6861db264b650a65f 155 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 13 35 - T 28-03-2018 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-539107 CU254_RS31525 5de3fcfd487499a6861db264b650a65f 155 PRINTS PR00070 Dihydrofolate reductase signature 40 51 1.0E-16 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CU254_RS31525 5de3fcfd487499a6861db264b650a65f 155 PRINTS PR00070 Dihydrofolate reductase signature 13 23 1.0E-16 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CU254_RS31525 5de3fcfd487499a6861db264b650a65f 155 PRINTS PR00070 Dihydrofolate reductase signature 27 35 1.0E-16 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CU254_RS31525 5de3fcfd487499a6861db264b650a65f 155 PRINTS PR00070 Dihydrofolate reductase signature 89 103 1.0E-16 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CU254_RS31525 5de3fcfd487499a6861db264b650a65f 155 PIRSF PIRSF000194 1 151 5.7E-49 T 28-03-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0009165|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CU254_RS31525 5de3fcfd487499a6861db264b650a65f 155 Pfam PF00186 Dihydrofolate reductase 1 130 1.4E-47 T 28-03-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0006545|GO:0009165|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 CU254_RS11100 2e79c3dc65d7b762ffd9fe40976edbdc 263 SUPERFAMILY SSF51658 13 225 1.21E-10 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CU254_RS11100 2e79c3dc65d7b762ffd9fe40976edbdc 263 Gene3D G3DSA:3.20.20.150 1 263 4.6E-73 T 28-03-2018 CU254_RS11100 2e79c3dc65d7b762ffd9fe40976edbdc 263 Pfam PF05114 Protein of unknown function (DUF692) 2 260 3.1E-84 T 28-03-2018 IPR007801 Uncharacterised protein family UPF0276 CU254_RS31635 3d38f5d5c061c48f25d60c68cbb0e3bc 346 SUPERFAMILY SSF51905 5 268 1.35E-21 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS31635 3d38f5d5c061c48f25d60c68cbb0e3bc 346 Gene3D G3DSA:3.50.50.60 2 83 1.0E-12 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS31635 3d38f5d5c061c48f25d60c68cbb0e3bc 346 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 1.1E-7 T 28-03-2018 CU254_RS31635 3d38f5d5c061c48f25d60c68cbb0e3bc 346 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 218 240 1.1E-7 T 28-03-2018 CU254_RS31635 3d38f5d5c061c48f25d60c68cbb0e3bc 346 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 129 147 1.1E-7 T 28-03-2018 CU254_RS31635 3d38f5d5c061c48f25d60c68cbb0e3bc 346 Gene3D G3DSA:3.50.50.60 195 309 0.0023 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS31635 3d38f5d5c061c48f25d60c68cbb0e3bc 346 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 240 7.5E-23 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS31635 3d38f5d5c061c48f25d60c68cbb0e3bc 346 Gene3D G3DSA:3.50.50.60 84 194 6.7E-15 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS34055 88caef813154f9ad89df2dd7f7b171af 251 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 144 172 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS34055 88caef813154f9ad89df2dd7f7b171af 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 2.9E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS34055 88caef813154f9ad89df2dd7f7b171af 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 2.9E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS34055 88caef813154f9ad89df2dd7f7b171af 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 2.9E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS34055 88caef813154f9ad89df2dd7f7b171af 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 2.9E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS34055 88caef813154f9ad89df2dd7f7b171af 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 2.9E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS34055 88caef813154f9ad89df2dd7f7b171af 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 2.9E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS34055 88caef813154f9ad89df2dd7f7b171af 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 248 1.4E-69 T 28-03-2018 CU254_RS34055 88caef813154f9ad89df2dd7f7b171af 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 9.3E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS34055 88caef813154f9ad89df2dd7f7b171af 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 9.3E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS34055 88caef813154f9ad89df2dd7f7b171af 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 137 145 9.3E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS34055 88caef813154f9ad89df2dd7f7b171af 251 Gene3D G3DSA:3.40.50.10090 5 51 1.8E-6 T 28-03-2018 CU254_RS34055 88caef813154f9ad89df2dd7f7b171af 251 Gene3D G3DSA:3.40.50.720 52 251 2.5E-68 T 28-03-2018 CU254_RS34055 88caef813154f9ad89df2dd7f7b171af 251 SUPERFAMILY SSF51735 12 249 6.14E-80 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS42310 4338a178d050d80563a50d8e31dd3c31 181 Gene3D G3DSA:1.10.10.10 135 172 0.33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS42310 4338a178d050d80563a50d8e31dd3c31 181 SUPERFAMILY SSF47413 27 90 4.16E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS42310 4338a178d050d80563a50d8e31dd3c31 181 Pfam PF01381 Helix-turn-helix 93 147 1.3E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS42310 4338a178d050d80563a50d8e31dd3c31 181 Pfam PF01381 Helix-turn-helix 29 83 1.6E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS42310 4338a178d050d80563a50d8e31dd3c31 181 SMART SM00530 28 83 9.0E-16 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS42310 4338a178d050d80563a50d8e31dd3c31 181 SMART SM00530 92 147 1.5E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS42310 4338a178d050d80563a50d8e31dd3c31 181 Gene3D G3DSA:1.10.260.40 24 91 9.5E-17 T 28-03-2018 CU254_RS42310 4338a178d050d80563a50d8e31dd3c31 181 Gene3D G3DSA:1.10.260.40 92 134 1.2E-10 T 28-03-2018 CU254_RS42310 4338a178d050d80563a50d8e31dd3c31 181 SUPERFAMILY SSF47413 93 150 6.19E-10 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS35185 505f172454dc0a59324df514937c1f4d 264 Gene3D G3DSA:3.60.21.10 1 258 1.2E-35 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CU254_RS35185 505f172454dc0a59324df514937c1f4d 264 Pfam PF00149 Calcineurin-like phosphoesterase 1 216 5.1E-11 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CU254_RS35185 505f172454dc0a59324df514937c1f4d 264 SUPERFAMILY SSF56300 1 247 1.03E-36 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CU254_RS04395 42a52fe02e6c3bc9876548c1e0328942 261 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 72 244 1.9E-12 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS04395 42a52fe02e6c3bc9876548c1e0328942 261 SUPERFAMILY SSF161098 2 257 2.73E-50 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS04395 42a52fe02e6c3bc9876548c1e0328942 261 Gene3D G3DSA:1.10.3720.10 1 252 6.0E-35 T 28-03-2018 CU254_RS35660 e762a73920adb9a6334bab7f60660048 150 Pfam PF12802 MarR family 39 98 1.7E-9 T 28-03-2018 CU254_RS35660 e762a73920adb9a6334bab7f60660048 150 SMART SM00347 33 136 3.0E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS35660 e762a73920adb9a6334bab7f60660048 150 Gene3D G3DSA:1.10.10.10 4 149 3.0E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS35660 e762a73920adb9a6334bab7f60660048 150 SUPERFAMILY SSF46785 28 134 4.71E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS32630 cf3e3d9be91047c974b7793fb1f8f333 326 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 325 3.2E-41 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS32630 cf3e3d9be91047c974b7793fb1f8f333 326 Gene3D G3DSA:1.10.3720.10 3 314 2.2E-42 T 28-03-2018 CU254_RS32630 cf3e3d9be91047c974b7793fb1f8f333 326 SUPERFAMILY SSF161098 92 160 9.37E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS32630 cf3e3d9be91047c974b7793fb1f8f333 326 SUPERFAMILY SSF161098 188 309 9.37E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS38015 a0f0bf3b4c8db54a621af7e0c9df9e92 304 Pfam PF00248 Aldo/keto reductase family 16 302 5.9E-66 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS38015 a0f0bf3b4c8db54a621af7e0c9df9e92 304 Gene3D G3DSA:3.20.20.100 1 304 2.9E-80 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS38015 a0f0bf3b4c8db54a621af7e0c9df9e92 304 SUPERFAMILY SSF51430 2 302 1.7E-85 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS25565 442e6359e0ac0647f811efe83260b61c 202 Gene3D G3DSA:1.10.357.10 2 192 6.4E-36 T 28-03-2018 CU254_RS25565 442e6359e0ac0647f811efe83260b61c 202 SUPERFAMILY SSF48498 84 188 3.39E-14 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS25565 442e6359e0ac0647f811efe83260b61c 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 1.1E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS25565 442e6359e0ac0647f811efe83260b61c 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 1.1E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS25565 442e6359e0ac0647f811efe83260b61c 202 SUPERFAMILY SSF46689 8 80 8.03E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS25565 442e6359e0ac0647f811efe83260b61c 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 63 7.5E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS18250 38c31f40e74568b85bf3fe4bba46844f 116 Pfam PF03795 YCII-related domain 1 115 1.3E-21 T 28-03-2018 IPR005545 YCII-related CU254_RS18250 38c31f40e74568b85bf3fe4bba46844f 116 Gene3D G3DSA:3.30.70.1060 1 116 1.4E-32 T 28-03-2018 CU254_RS18250 38c31f40e74568b85bf3fe4bba46844f 116 SUPERFAMILY SSF54909 1 112 6.43E-25 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS03850 61bceaf99c6b08e3775825beabf1652d 391 Pfam PF00005 ABC transporter 21 162 2.8E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS03850 61bceaf99c6b08e3775825beabf1652d 391 Gene3D G3DSA:3.40.50.300 1 238 4.0E-70 T 28-03-2018 CU254_RS03850 61bceaf99c6b08e3775825beabf1652d 391 SUPERFAMILY SSF52540 4 244 1.33E-82 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS03850 61bceaf99c6b08e3775825beabf1652d 391 SUPERFAMILY SSF50331 237 387 5.74E-21 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CU254_RS03850 61bceaf99c6b08e3775825beabf1652d 391 Gene3D G3DSA:2.40.50.140 293 372 9.1E-17 T 28-03-2018 CU254_RS03850 61bceaf99c6b08e3775825beabf1652d 391 Gene3D G3DSA:2.40.50.100 240 292 8.4E-16 T 28-03-2018 CU254_RS03850 61bceaf99c6b08e3775825beabf1652d 391 SMART SM00382 29 220 6.7E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS03850 61bceaf99c6b08e3775825beabf1652d 391 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS21725 2288306ff50b55bafbb541d9fa9b53de 95 SUPERFAMILY SSF47336 14 90 1.44E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS21725 2288306ff50b55bafbb541d9fa9b53de 95 Pfam PF00550 Phosphopantetheine attachment site 16 74 8.2E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS21725 2288306ff50b55bafbb541d9fa9b53de 95 Gene3D G3DSA:1.10.1200.10 5 95 3.1E-15 T 28-03-2018 CU254_RS34650 ad350974f7d3e72e1fdf2f05b43a595f 272 SUPERFAMILY SSF51679 6 258 1.77E-33 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS34650 ad350974f7d3e72e1fdf2f05b43a595f 272 Gene3D G3DSA:3.20.20.30 12 134 1.8E-26 T 28-03-2018 CU254_RS34650 ad350974f7d3e72e1fdf2f05b43a595f 272 Gene3D G3DSA:3.20.20.30 135 271 1.3E-7 T 28-03-2018 CU254_RS34650 ad350974f7d3e72e1fdf2f05b43a595f 272 Pfam PF00296 Luciferase-like monooxygenase 136 200 2.5E-6 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS34650 ad350974f7d3e72e1fdf2f05b43a595f 272 Pfam PF00296 Luciferase-like monooxygenase 13 133 1.8E-18 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS33735 b6c816796a7191369269fea33c6d1898 198 ProSitePatterns PS01081 TetR-type HTH domain signature. 24 54 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CU254_RS33735 b6c816796a7191369269fea33c6d1898 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 56 1.5E-17 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS33735 b6c816796a7191369269fea33c6d1898 198 Gene3D G3DSA:1.10.10.60 2 58 1.6E-20 T 28-03-2018 CU254_RS33735 b6c816796a7191369269fea33c6d1898 198 Gene3D G3DSA:1.10.357.10 59 192 3.9E-17 T 28-03-2018 CU254_RS33735 b6c816796a7191369269fea33c6d1898 198 SUPERFAMILY SSF48498 88 189 3.34E-9 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS33735 b6c816796a7191369269fea33c6d1898 198 SUPERFAMILY SSF46689 3 78 1.21E-20 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS33735 b6c816796a7191369269fea33c6d1898 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 2.5E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS33735 b6c816796a7191369269fea33c6d1898 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 2.5E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS30480 d236b3521fab471ababc052a72a75029 456 Pfam PF13520 Amino acid permease 34 414 7.6E-32 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CU254_RS30480 d236b3521fab471ababc052a72a75029 456 PIRSF PIRSF006060 7 450 4.9E-53 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CU254_RS40630 7b1e21835fbb842159f9bd80900dce70 210 Pfam PF01738 Dienelactone hydrolase family 71 208 3.2E-18 T 28-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 CU254_RS40630 7b1e21835fbb842159f9bd80900dce70 210 SUPERFAMILY SSF53474 4 209 1.0E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS40630 7b1e21835fbb842159f9bd80900dce70 210 Gene3D G3DSA:3.40.50.1820 2 210 1.3E-24 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS17455 aac65affdc379470abd7d3305f914cb1 514 SUPERFAMILY SSF56801 3 508 1.96E-143 T 28-03-2018 CU254_RS17455 aac65affdc379470abd7d3305f914cb1 514 Pfam PF00501 AMP-binding enzyme 8 411 3.8E-90 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS17455 aac65affdc379470abd7d3305f914cb1 514 Gene3D G3DSA:3.40.50.980 1 169 5.4E-29 T 28-03-2018 CU254_RS17455 aac65affdc379470abd7d3305f914cb1 514 Gene3D G3DSA:3.40.50.980 170 321 7.0E-39 T 28-03-2018 CU254_RS17455 aac65affdc379470abd7d3305f914cb1 514 Gene3D G3DSA:3.30.300.30 406 514 1.8E-31 T 28-03-2018 CU254_RS17455 aac65affdc379470abd7d3305f914cb1 514 Gene3D G3DSA:2.30.38.10 322 404 1.8E-28 T 28-03-2018 CU254_RS17455 aac65affdc379470abd7d3305f914cb1 514 ProSitePatterns PS00455 Putative AMP-binding domain signature. 163 174 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS17455 aac65affdc379470abd7d3305f914cb1 514 Pfam PF13193 AMP-binding enzyme C-terminal domain 420 495 1.0E-20 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS12535 037738d50c63ae46e7c9c4e5b7609382 181 Pfam PF12840 Helix-turn-helix domain 12 66 6.9E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS12535 037738d50c63ae46e7c9c4e5b7609382 181 SUPERFAMILY SSF46785 10 117 1.22E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS12535 037738d50c63ae46e7c9c4e5b7609382 181 Gene3D G3DSA:1.10.10.10 3 172 5.2E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS19555 afa76b51588fbd89b6d12c0d62a091c1 315 Pfam PF00248 Aldo/keto reductase family 16 313 5.3E-64 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS19555 afa76b51588fbd89b6d12c0d62a091c1 315 SUPERFAMILY SSF51430 4 313 1.3E-84 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS19555 afa76b51588fbd89b6d12c0d62a091c1 315 PRINTS PR00069 Aldo-keto reductase signature 140 157 4.4E-6 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CU254_RS19555 afa76b51588fbd89b6d12c0d62a091c1 315 PRINTS PR00069 Aldo-keto reductase signature 109 127 4.4E-6 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CU254_RS19555 afa76b51588fbd89b6d12c0d62a091c1 315 Gene3D G3DSA:3.20.20.100 1 315 3.7E-76 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS34015 4199b74ddab1ad5cf068a5afbfd67fa0 431 Gene3D G3DSA:3.30.565.10 306 431 1.3E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS34015 4199b74ddab1ad5cf068a5afbfd67fa0 431 SUPERFAMILY SSF55874 320 430 5.87E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS34015 4199b74ddab1ad5cf068a5afbfd67fa0 431 Pfam PF13796 Putative sensor 59 215 7.6E-19 T 28-03-2018 IPR025828 Putative sensor domain CU254_RS34015 4199b74ddab1ad5cf068a5afbfd67fa0 431 Pfam PF07730 Histidine kinase 244 310 2.6E-14 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CU254_RS38120 d3f70e1a190d0deef894b81efe0a88f0 874 Gene3D G3DSA:2.60.40.1120 702 783 5.6E-14 T 28-03-2018 CU254_RS38120 d3f70e1a190d0deef894b81efe0a88f0 874 Gene3D G3DSA:2.60.40.1120 617 701 3.5E-11 T 28-03-2018 CU254_RS38120 d3f70e1a190d0deef894b81efe0a88f0 874 Gene3D G3DSA:2.60.40.1120 786 872 1.1E-10 T 28-03-2018 CU254_RS38120 d3f70e1a190d0deef894b81efe0a88f0 874 Pfam PF07690 Major Facilitator Superfamily 38 436 3.1E-52 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS38120 d3f70e1a190d0deef894b81efe0a88f0 874 Pfam PF13620 Carboxypeptidase regulatory-like domain 788 857 6.0E-11 T 28-03-2018 CU254_RS38120 d3f70e1a190d0deef894b81efe0a88f0 874 Pfam PF13620 Carboxypeptidase regulatory-like domain 618 696 3.0E-12 T 28-03-2018 CU254_RS38120 d3f70e1a190d0deef894b81efe0a88f0 874 Pfam PF13620 Carboxypeptidase regulatory-like domain 701 780 6.2E-13 T 28-03-2018 CU254_RS38120 d3f70e1a190d0deef894b81efe0a88f0 874 SUPERFAMILY SSF49464 787 871 2.04E-10 T 28-03-2018 IPR008969 Carboxypeptidase-like, regulatory domain CU254_RS38120 d3f70e1a190d0deef894b81efe0a88f0 874 Gene3D G3DSA:1.20.1250.20 278 523 3.1E-31 T 28-03-2018 CU254_RS38120 d3f70e1a190d0deef894b81efe0a88f0 874 Gene3D G3DSA:1.20.1250.20 26 225 4.5E-32 T 28-03-2018 CU254_RS38120 d3f70e1a190d0deef894b81efe0a88f0 874 SUPERFAMILY SSF103473 274 446 5.36E-69 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS38120 d3f70e1a190d0deef894b81efe0a88f0 874 SUPERFAMILY SSF103473 17 221 5.36E-69 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS38120 d3f70e1a190d0deef894b81efe0a88f0 874 SUPERFAMILY SSF103473 494 519 5.36E-69 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS38120 d3f70e1a190d0deef894b81efe0a88f0 874 SUPERFAMILY SSF49464 701 792 7.85E-13 T 28-03-2018 IPR008969 Carboxypeptidase-like, regulatory domain CU254_RS38120 d3f70e1a190d0deef894b81efe0a88f0 874 SUPERFAMILY SSF49464 618 705 2.0E-11 T 28-03-2018 IPR008969 Carboxypeptidase-like, regulatory domain CU254_RS38120 d3f70e1a190d0deef894b81efe0a88f0 874 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 34 517 2.8E-78 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CU254_RS29620 d2e92aefc5eb7e87e1d377e0d786a8bb 231 Pfam PF00005 ABC transporter 20 155 3.6E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS29620 d2e92aefc5eb7e87e1d377e0d786a8bb 231 SMART SM00382 28 189 9.5E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS29620 d2e92aefc5eb7e87e1d377e0d786a8bb 231 Gene3D G3DSA:3.40.50.300 1 231 1.1E-48 T 28-03-2018 CU254_RS29620 d2e92aefc5eb7e87e1d377e0d786a8bb 231 SUPERFAMILY SSF52540 4 223 1.02E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS29620 d2e92aefc5eb7e87e1d377e0d786a8bb 231 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS33325 5de1491b1ac3360928bb76441e973dea 246 Gene3D G3DSA:3.40.50.300 5 245 3.8E-61 T 28-03-2018 CU254_RS33325 5de1491b1ac3360928bb76441e973dea 246 SUPERFAMILY SSF52540 9 227 3.17E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS33325 5de1491b1ac3360928bb76441e973dea 246 SMART SM00382 37 223 5.2E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS33325 5de1491b1ac3360928bb76441e973dea 246 Pfam PF00005 ABC transporter 28 174 1.1E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS33325 5de1491b1ac3360928bb76441e973dea 246 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS15650 5c4efd26368afd13f9be1c735ee009e0 224 Pfam PF00881 Nitroreductase family 12 199 3.1E-31 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CU254_RS15650 5c4efd26368afd13f9be1c735ee009e0 224 Gene3D G3DSA:3.40.109.10 2 220 1.0E-50 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CU254_RS15650 5c4efd26368afd13f9be1c735ee009e0 224 SUPERFAMILY SSF55469 10 222 1.57E-39 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CU254_RS23530 9a4aae1b51c9f8e29866aa2fee4d6799 424 SUPERFAMILY SSF56796 13 422 2.75E-102 T 28-03-2018 CU254_RS23530 9a4aae1b51c9f8e29866aa2fee4d6799 424 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 184 212 - T 28-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 CU254_RS23530 9a4aae1b51c9f8e29866aa2fee4d6799 424 Gene3D G3DSA:3.40.50.1970 17 194 2.1E-45 T 28-03-2018 CU254_RS23530 9a4aae1b51c9f8e29866aa2fee4d6799 424 Pfam PF00465 Iron-containing alcohol dehydrogenase 19 415 6.8E-109 T 28-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 CU254_RS23530 9a4aae1b51c9f8e29866aa2fee4d6799 424 Gene3D G3DSA:1.20.1090.10 196 424 1.9E-50 T 28-03-2018 CU254_RS16020 885fadd51b77bde6c1b2fb28379d2e02 65 Gene3D G3DSA:3.90.820.10 1 63 6.8E-31 T 28-03-2018 CU254_RS16020 885fadd51b77bde6c1b2fb28379d2e02 65 SUPERFAMILY SSF160582 2 63 7.19E-28 T 28-03-2018 CU254_RS16020 885fadd51b77bde6c1b2fb28379d2e02 65 SMART SM00923 2 48 3.0E-19 T 28-03-2018 IPR005153 MbtH-like protein CU254_RS16020 885fadd51b77bde6c1b2fb28379d2e02 65 Pfam PF03621 MbtH-like protein 3 48 5.8E-21 T 28-03-2018 IPR005153 MbtH-like protein CU254_RS35870 a849b5d911f07bbc18be1e79593e7490 167 Pfam PF00866 Ring hydroxylating beta subunit 21 156 6.4E-17 T 28-03-2018 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0003824|GO:0006725|GO:0055114 CU254_RS35870 a849b5d911f07bbc18be1e79593e7490 167 SUPERFAMILY SSF54427 11 166 3.57E-35 T 28-03-2018 IPR032710 NTF2-like domain CU254_RS35870 a849b5d911f07bbc18be1e79593e7490 167 Gene3D G3DSA:3.10.450.50 2 167 6.1E-18 T 28-03-2018 CU254_RS40655 6e31926e0ffaa0e7cf3de69d8d20b7bf 268 TIGRFAM TIGR03891 thiopep_ocin: thiopeptide-type bacteriocin biosynthesis domain 10 259 3.1E-19 T 28-03-2018 IPR023809 Thiopeptide-type bacteriocin biosynthesis domain CU254_RS40655 6e31926e0ffaa0e7cf3de69d8d20b7bf 268 Pfam PF14028 Lantibiotic biosynthesis dehydratase C-term 10 259 1.1E-21 T 28-03-2018 IPR023809 Thiopeptide-type bacteriocin biosynthesis domain CU254_RS31450 db522283cb783d68584581319a27e139 559 SUPERFAMILY SSF52821 427 544 1.31E-20 T 28-03-2018 IPR001763 Rhodanese-like domain CU254_RS31450 db522283cb783d68584581319a27e139 559 Pfam PF00581 Rhodanese-like domain 437 536 1.3E-9 T 28-03-2018 IPR001763 Rhodanese-like domain CU254_RS31450 db522283cb783d68584581319a27e139 559 SMART SM00450 434 540 4.6E-8 T 28-03-2018 IPR001763 Rhodanese-like domain CU254_RS31450 db522283cb783d68584581319a27e139 559 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 14 398 2.1E-24 T 28-03-2018 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 CU254_RS31450 db522283cb783d68584581319a27e139 559 Gene3D G3DSA:3.40.250.10 425 554 3.2E-19 T 28-03-2018 IPR001763 Rhodanese-like domain CU254_RS13310 5f0e7394eacd636c09f1971a5c7e3f22 279 Pfam PF00248 Aldo/keto reductase family 28 262 2.5E-50 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS13310 5f0e7394eacd636c09f1971a5c7e3f22 279 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 45 62 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CU254_RS13310 5f0e7394eacd636c09f1971a5c7e3f22 279 Gene3D G3DSA:3.20.20.100 1 278 1.6E-98 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS13310 5f0e7394eacd636c09f1971a5c7e3f22 279 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 129 146 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CU254_RS13310 5f0e7394eacd636c09f1971a5c7e3f22 279 PRINTS PR00069 Aldo-keto reductase signature 97 115 2.6E-53 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CU254_RS13310 5f0e7394eacd636c09f1971a5c7e3f22 279 PRINTS PR00069 Aldo-keto reductase signature 41 65 2.6E-53 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CU254_RS13310 5f0e7394eacd636c09f1971a5c7e3f22 279 PRINTS PR00069 Aldo-keto reductase signature 129 146 2.6E-53 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CU254_RS13310 5f0e7394eacd636c09f1971a5c7e3f22 279 PRINTS PR00069 Aldo-keto reductase signature 163 192 2.6E-53 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CU254_RS13310 5f0e7394eacd636c09f1971a5c7e3f22 279 PRINTS PR00069 Aldo-keto reductase signature 200 224 2.6E-53 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CU254_RS13310 5f0e7394eacd636c09f1971a5c7e3f22 279 SUPERFAMILY SSF51430 13 272 8.77E-96 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS13310 5f0e7394eacd636c09f1971a5c7e3f22 279 PIRSF PIRSF000097 116 276 5.4E-46 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CU254_RS13310 5f0e7394eacd636c09f1971a5c7e3f22 279 PIRSF PIRSF000097 4 123 2.6E-41 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CU254_RS26545 1cbfce23df8a4b45c70fadc92cc71cf1 460 SUPERFAMILY SSF51338 1 67 4.65E-13 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS26545 1cbfce23df8a4b45c70fadc92cc71cf1 460 SUPERFAMILY SSF51338 358 454 3.87E-34 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS26545 1cbfce23df8a4b45c70fadc92cc71cf1 460 Gene3D G3DSA:3.20.20.140 68 278 6.4E-61 T 28-03-2018 CU254_RS26545 1cbfce23df8a4b45c70fadc92cc71cf1 460 Gene3D G3DSA:3.20.20.140 279 422 5.0E-42 T 28-03-2018 CU254_RS26545 1cbfce23df8a4b45c70fadc92cc71cf1 460 SUPERFAMILY SSF51556 53 381 3.77E-108 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS26545 1cbfce23df8a4b45c70fadc92cc71cf1 460 TIGRFAM TIGR02033 D-hydantoinase: dihydropyrimidinase 3 453 2.8E-178 T 28-03-2018 IPR011778 Hydantoinase/dihydropyrimidinase GO:0005737 Reactome: R-HSA-399956 CU254_RS26545 1cbfce23df8a4b45c70fadc92cc71cf1 460 Gene3D G3DSA:2.30.40.10 2 67 2.4E-18 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS26545 1cbfce23df8a4b45c70fadc92cc71cf1 460 Pfam PF01979 Amidohydrolase family 49 435 1.5E-29 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CU254_RS15730 9abb54e54595eef2c13fb95d784745e0 168 SUPERFAMILY SSF47741 88 156 2.88E-30 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CU254_RS15730 9abb54e54595eef2c13fb95d784745e0 168 Gene3D G3DSA:3.10.20.30 2 78 3.7E-27 T 28-03-2018 IPR012675 Beta-grasp domain CU254_RS15730 9abb54e54595eef2c13fb95d784745e0 168 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 10 63 2.0E-8 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CU254_RS15730 9abb54e54595eef2c13fb95d784745e0 168 SUPERFAMILY SSF54292 8 92 8.91E-26 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CU254_RS15730 9abb54e54595eef2c13fb95d784745e0 168 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 43 51 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CU254_RS15730 9abb54e54595eef2c13fb95d784745e0 168 Gene3D G3DSA:1.10.150.120 79 168 2.5E-35 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CU254_RS15730 9abb54e54595eef2c13fb95d784745e0 168 Pfam PF01799 [2Fe-2S] binding domain 77 149 6.2E-29 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CU254_RS02075 ff79f83b021323d29e6d799d0b482bf8 37 SUPERFAMILY SSF57840 2 37 2.49E-15 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS02075 ff79f83b021323d29e6d799d0b482bf8 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS02075 ff79f83b021323d29e6d799d0b482bf8 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 9 37 4.0E-9 T 28-03-2018 CU254_RS02075 ff79f83b021323d29e6d799d0b482bf8 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 16.29 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS02075 ff79f83b021323d29e6d799d0b482bf8 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 2 37 6.6E-21 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS02075 ff79f83b021323d29e6d799d0b482bf8 37 Pfam PF00444 Ribosomal protein L36 2 37 1.8E-16 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS14840 22923070e1801b3db3b8ce772e0133ce 207 Pfam PF04404 ERF superfamily 9 143 2.5E-19 T 28-03-2018 IPR007499 Essential recombination function protein CU254_RS38890 e5923692bf7b3b8d63ba498018a9c960 884 Pfam PF00905 Penicillin binding protein transpeptidase domain 475 757 4.3E-26 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CU254_RS38890 e5923692bf7b3b8d63ba498018a9c960 884 SUPERFAMILY SSF56601 367 387 6.99E-68 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CU254_RS38890 e5923692bf7b3b8d63ba498018a9c960 884 SUPERFAMILY SSF56601 418 801 6.99E-68 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CU254_RS38890 e5923692bf7b3b8d63ba498018a9c960 884 Gene3D G3DSA:1.10.3810.10 205 401 4.0E-55 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CU254_RS38890 e5923692bf7b3b8d63ba498018a9c960 884 Gene3D G3DSA:3.40.710.10 402 841 3.2E-74 T 28-03-2018 CU254_RS38890 e5923692bf7b3b8d63ba498018a9c960 884 SUPERFAMILY SSF53955 201 405 9.56E-54 T 28-03-2018 IPR023346 Lysozyme-like domain CU254_RS38890 e5923692bf7b3b8d63ba498018a9c960 884 Pfam PF00912 Transglycosylase 221 383 9.6E-47 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CU254_RS12675 370182d6493a8e2bfbf15a435fb991e2 112 Gene3D G3DSA:1.10.10.10 3 102 3.2E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS12675 370182d6493a8e2bfbf15a435fb991e2 112 SUPERFAMILY SSF46785 13 90 8.33E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS12675 370182d6493a8e2bfbf15a435fb991e2 112 Pfam PF13601 Winged helix DNA-binding domain 13 89 5.1E-19 T 28-03-2018 IPR027395 Winged helix DNA-binding domain CU254_RS17995 c71e1bc4253273ee70d4a2c5f3d5e36a 264 SUPERFAMILY SSF55729 82 257 3.09E-22 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS17995 c71e1bc4253273ee70d4a2c5f3d5e36a 264 Pfam PF00583 Acetyltransferase (GNAT) family 152 248 1.8E-6 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS17995 c71e1bc4253273ee70d4a2c5f3d5e36a 264 Gene3D G3DSA:3.40.630.30 115 262 1.5E-21 T 28-03-2018 CU254_RS15105 db52134496f65164901bc9167969ebb3 362 Gene3D G3DSA:1.10.10.10 17 73 8.2E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS15105 db52134496f65164901bc9167969ebb3 362 Gene3D G3DSA:3.30.420.40 74 203 5.3E-12 T 28-03-2018 CU254_RS15105 db52134496f65164901bc9167969ebb3 362 Pfam PF00480 ROK family 123 240 1.8E-9 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CU254_RS15105 db52134496f65164901bc9167969ebb3 362 Pfam PF12802 MarR family 14 67 2.7E-7 T 28-03-2018 CU254_RS15105 db52134496f65164901bc9167969ebb3 362 Gene3D G3DSA:3.30.420.40 204 362 2.6E-20 T 28-03-2018 CU254_RS15105 db52134496f65164901bc9167969ebb3 362 SUPERFAMILY SSF53067 92 346 1.71E-21 T 28-03-2018 CU254_RS15105 db52134496f65164901bc9167969ebb3 362 SUPERFAMILY SSF46785 8 82 8.93E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS09835 a4f0bcef7ea498b4f9bfca0891105031 507 Pfam PF13600 N-terminal domain of unknown function (DUF4140) 8 104 4.2E-19 T 28-03-2018 IPR025554 Domain of unknown function DUF4140 CU254_RS09835 a4f0bcef7ea498b4f9bfca0891105031 507 Gene3D G3DSA:2.60.40.1580 402 502 1.0E-5 T 28-03-2018 CU254_RS09835 a4f0bcef7ea498b4f9bfca0891105031 507 TIGRFAM TIGR02231 TIGR02231: conserved hypothetical protein 5 502 2.7E-97 T 28-03-2018 IPR011935 Conserved hypothetical protein CHP02231 CU254_RS09835 a4f0bcef7ea498b4f9bfca0891105031 507 Pfam PF13598 Domain of unknown function (DUF4139) 194 497 5.1E-54 T 28-03-2018 IPR011935 Conserved hypothetical protein CHP02231 CU254_RS05555 a389cb998d3614e91eee1c982be9205e 159 SUPERFAMILY SSF54593 7 138 1.21E-17 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS05555 a389cb998d3614e91eee1c982be9205e 159 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 72 2.8E-4 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CU254_RS05555 a389cb998d3614e91eee1c982be9205e 159 Gene3D G3DSA:3.10.180.10 3 157 1.5E-18 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS40215 af27b0c41570347c746bb30b63e78865 309 Gene3D G3DSA:3.40.50.720 5 175 1.5E-28 T 28-03-2018 CU254_RS40215 af27b0c41570347c746bb30b63e78865 309 Pfam PF01370 NAD dependent epimerase/dehydratase family 8 242 1.9E-46 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CU254_RS40215 af27b0c41570347c746bb30b63e78865 309 SUPERFAMILY SSF51735 1 306 1.88E-83 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS40215 af27b0c41570347c746bb30b63e78865 309 Gene3D G3DSA:3.90.25.10 176 308 2.7E-37 T 28-03-2018 CU254_RS26745 7ff96c377ac647491e77ec3977bec97c 282 Pfam PF02645 Uncharacterised protein, DegV family COG1307 3 279 6.9E-80 T 28-03-2018 IPR003797 DegV CU254_RS26745 7ff96c377ac647491e77ec3977bec97c 282 Gene3D G3DSA:3.40.50.10170 1 152 1.1E-48 T 28-03-2018 CU254_RS26745 7ff96c377ac647491e77ec3977bec97c 282 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 3 278 1.6E-83 T 28-03-2018 IPR003797 DegV CU254_RS26745 7ff96c377ac647491e77ec3977bec97c 282 SUPERFAMILY SSF82549 2 278 1.83E-76 T 28-03-2018 CU254_RS26745 7ff96c377ac647491e77ec3977bec97c 282 Gene3D G3DSA:3.30.1180.10 153 282 3.1E-41 T 28-03-2018 CU254_RS30380 0c0987afc99d4f233499e582e9fb6e02 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 56 1.3E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS30380 0c0987afc99d4f233499e582e9fb6e02 198 SUPERFAMILY SSF48498 80 184 1.16E-21 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS30380 0c0987afc99d4f233499e582e9fb6e02 198 Gene3D G3DSA:1.10.10.60 2 52 2.9E-10 T 28-03-2018 CU254_RS30380 0c0987afc99d4f233499e582e9fb6e02 198 SUPERFAMILY SSF46689 6 73 3.49E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS30380 0c0987afc99d4f233499e582e9fb6e02 198 Gene3D G3DSA:1.10.357.10 53 189 8.4E-21 T 28-03-2018 CU254_RS39825 e50d77a5b3e04df156107d932e696281 174 Gene3D G3DSA:1.10.1740.10 7 80 1.5E-16 T 28-03-2018 CU254_RS39825 e50d77a5b3e04df156107d932e696281 174 Gene3D G3DSA:1.10.10.10 81 169 1.2E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS39825 e50d77a5b3e04df156107d932e696281 174 Pfam PF04542 Sigma-70 region 2 17 84 9.0E-11 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS39825 e50d77a5b3e04df156107d932e696281 174 SUPERFAMILY SSF88946 13 101 4.45E-13 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS39825 e50d77a5b3e04df156107d932e696281 174 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 16 161 1.3E-16 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS39825 e50d77a5b3e04df156107d932e696281 174 Pfam PF08281 Sigma-70, region 4 112 160 4.2E-8 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS39825 e50d77a5b3e04df156107d932e696281 174 SUPERFAMILY SSF88659 105 165 6.54E-10 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS41415 f932572046721a999d6c4899ee46117c 196 SUPERFAMILY SSF55729 7 172 2.34E-24 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS41415 f932572046721a999d6c4899ee46117c 196 Gene3D G3DSA:3.40.630.30 4 183 3.8E-22 T 28-03-2018 CU254_RS41415 f932572046721a999d6c4899ee46117c 196 Pfam PF13302 Acetyltransferase (GNAT) domain 16 151 4.0E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS23730 b95a4485e42d41bb8fdd73125d71f6c5 299 Pfam PF01435 Peptidase family M48 151 198 8.1E-6 T 28-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CU254_RS23730 b95a4485e42d41bb8fdd73125d71f6c5 299 Gene3D G3DSA:3.30.2010.10 62 193 4.8E-10 T 28-03-2018 CU254_RS03775 495bfdc9eac5b709d69f0b0eaed1fc8d 510 Gene3D G3DSA:2.30.42.10 431 510 3.1E-17 T 28-03-2018 CU254_RS03775 495bfdc9eac5b709d69f0b0eaed1fc8d 510 SUPERFAMILY SSF50156 393 508 6.97E-18 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CU254_RS03775 495bfdc9eac5b709d69f0b0eaed1fc8d 510 SUPERFAMILY SSF50494 209 420 2.31E-52 T 28-03-2018 IPR009003 Peptidase S1, PA clan CU254_RS03775 495bfdc9eac5b709d69f0b0eaed1fc8d 510 Pfam PF13180 PDZ domain 425 507 2.1E-16 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CU254_RS03775 495bfdc9eac5b709d69f0b0eaed1fc8d 510 Gene3D G3DSA:2.40.10.10 205 312 1.5E-28 T 28-03-2018 CU254_RS03775 495bfdc9eac5b709d69f0b0eaed1fc8d 510 SMART SM00228 423 498 3.3E-10 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CU254_RS03775 495bfdc9eac5b709d69f0b0eaed1fc8d 510 PRINTS PR00834 HtrA/DegQ protease family signature 272 292 3.9E-46 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CU254_RS03775 495bfdc9eac5b709d69f0b0eaed1fc8d 510 PRINTS PR00834 HtrA/DegQ protease family signature 375 392 3.9E-46 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CU254_RS03775 495bfdc9eac5b709d69f0b0eaed1fc8d 510 PRINTS PR00834 HtrA/DegQ protease family signature 456 468 3.9E-46 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CU254_RS03775 495bfdc9eac5b709d69f0b0eaed1fc8d 510 PRINTS PR00834 HtrA/DegQ protease family signature 246 258 3.9E-46 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CU254_RS03775 495bfdc9eac5b709d69f0b0eaed1fc8d 510 PRINTS PR00834 HtrA/DegQ protease family signature 353 370 3.9E-46 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CU254_RS03775 495bfdc9eac5b709d69f0b0eaed1fc8d 510 PRINTS PR00834 HtrA/DegQ protease family signature 312 336 3.9E-46 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CU254_RS03775 495bfdc9eac5b709d69f0b0eaed1fc8d 510 Pfam PF13365 Trypsin-like peptidase domain 237 382 2.8E-31 T 28-03-2018 CU254_RS03775 495bfdc9eac5b709d69f0b0eaed1fc8d 510 Gene3D G3DSA:2.40.10.10 313 430 1.2E-33 T 28-03-2018 CU254_RS21160 6dd9c54b9f310da6cbaf203652292c8f 166 Pfam PF03551 Transcriptional regulator PadR-like family 7 78 3.2E-18 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CU254_RS21160 6dd9c54b9f310da6cbaf203652292c8f 166 SUPERFAMILY SSF46785 3 163 1.27E-33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS21160 6dd9c54b9f310da6cbaf203652292c8f 166 Gene3D G3DSA:1.10.10.10 1 87 2.6E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS19195 f4b130ec190cfaa915946c973e4de10f 162 Pfam PF04978 Protein of unknown function (DUF664) 15 158 1.7E-42 T 28-03-2018 IPR007061 Protein of unknown function DUF664 CU254_RS19195 f4b130ec190cfaa915946c973e4de10f 162 SUPERFAMILY SSF109854 9 158 1.4E-36 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CU254_RS19195 f4b130ec190cfaa915946c973e4de10f 162 Gene3D G3DSA:1.20.120.450 1 160 7.0E-29 T 28-03-2018 CU254_RS38065 8a57c5371fb6b1b0ccf928bfe2e4f889 396 Pfam PF01979 Amidohydrolase family 60 378 8.5E-27 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CU254_RS38065 8a57c5371fb6b1b0ccf928bfe2e4f889 396 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 12 375 5.5E-82 T 28-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 CU254_RS38065 8a57c5371fb6b1b0ccf928bfe2e4f889 396 Gene3D G3DSA:2.30.40.10 8 78 1.2E-17 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS38065 8a57c5371fb6b1b0ccf928bfe2e4f889 396 PIRSF PIRSF038994 10 390 5.3E-112 T 28-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 CU254_RS38065 8a57c5371fb6b1b0ccf928bfe2e4f889 396 Gene3D G3DSA:3.20.20.140 79 357 5.3E-107 T 28-03-2018 CU254_RS38065 8a57c5371fb6b1b0ccf928bfe2e4f889 396 SUPERFAMILY SSF51338 357 393 4.96E-17 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS38065 8a57c5371fb6b1b0ccf928bfe2e4f889 396 SUPERFAMILY SSF51338 6 63 4.96E-17 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS38065 8a57c5371fb6b1b0ccf928bfe2e4f889 396 SUPERFAMILY SSF51556 64 357 2.3E-95 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS23330 e1ad40f7c77e5ba8acc1c6ac1e612344 346 Gene3D G3DSA:3.40.50.2000 161 334 9.2E-10 T 28-03-2018 CU254_RS22080 50cb88206c9468757aa7ca0d376586e6 173 Gene3D G3DSA:3.90.1140.10 7 171 1.6E-12 T 28-03-2018 CU254_RS22080 50cb88206c9468757aa7ca0d376586e6 173 Pfam PF13563 2'-5' RNA ligase superfamily 32 156 5.3E-12 T 28-03-2018 CU254_RS20050 7050cf0b22fad9771da6e3df2830ae2e 215 Gene3D G3DSA:2.40.10.10 33 117 2.3E-11 T 28-03-2018 CU254_RS20050 7050cf0b22fad9771da6e3df2830ae2e 215 SUPERFAMILY SSF50494 50 208 1.27E-24 T 28-03-2018 IPR009003 Peptidase S1, PA clan CU254_RS20050 7050cf0b22fad9771da6e3df2830ae2e 215 Gene3D G3DSA:2.40.10.10 118 211 1.2E-14 T 28-03-2018 CU254_RS20050 7050cf0b22fad9771da6e3df2830ae2e 215 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 120 140 2.7E-25 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CU254_RS20050 7050cf0b22fad9771da6e3df2830ae2e 215 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 66 80 2.7E-25 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CU254_RS20050 7050cf0b22fad9771da6e3df2830ae2e 215 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 161 184 2.7E-25 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CU254_RS20050 7050cf0b22fad9771da6e3df2830ae2e 215 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 141 158 2.7E-25 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CU254_RS20050 7050cf0b22fad9771da6e3df2830ae2e 215 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 185 199 2.7E-25 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CU254_RS20260 e0a75750039020c93c10f00407d93864 568 Gene3D G3DSA:2.30.38.10 362 446 2.1E-19 T 28-03-2018 CU254_RS20260 e0a75750039020c93c10f00407d93864 568 Gene3D G3DSA:3.40.50.980 213 361 9.9E-34 T 28-03-2018 CU254_RS20260 e0a75750039020c93c10f00407d93864 568 Pfam PF13193 AMP-binding enzyme C-terminal domain 462 539 7.8E-19 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS20260 e0a75750039020c93c10f00407d93864 568 SUPERFAMILY SSF56801 20 550 4.06E-130 T 28-03-2018 CU254_RS20260 e0a75750039020c93c10f00407d93864 568 Gene3D G3DSA:3.40.50.980 41 212 4.2E-31 T 28-03-2018 CU254_RS20260 e0a75750039020c93c10f00407d93864 568 Pfam PF00501 AMP-binding enzyme 63 453 2.0E-75 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS20260 e0a75750039020c93c10f00407d93864 568 Gene3D G3DSA:3.30.300.30 449 562 1.5E-22 T 28-03-2018 CU254_RS01395 d6e43c4c9774cbd47a8dbf3845a1fec0 635 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 6 629 6.6E-220 T 28-03-2018 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS01395 d6e43c4c9774cbd47a8dbf3845a1fec0 635 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 80 105 6.0E-64 T 28-03-2018 CU254_RS01395 d6e43c4c9774cbd47a8dbf3845a1fec0 635 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 312 324 6.0E-64 T 28-03-2018 CU254_RS01395 d6e43c4c9774cbd47a8dbf3845a1fec0 635 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 108 128 6.0E-64 T 28-03-2018 CU254_RS01395 d6e43c4c9774cbd47a8dbf3845a1fec0 635 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 244 270 6.0E-64 T 28-03-2018 CU254_RS01395 d6e43c4c9774cbd47a8dbf3845a1fec0 635 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 419 438 6.0E-64 T 28-03-2018 CU254_RS01395 d6e43c4c9774cbd47a8dbf3845a1fec0 635 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 155 176 6.0E-64 T 28-03-2018 CU254_RS01395 d6e43c4c9774cbd47a8dbf3845a1fec0 635 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 222 243 6.0E-64 T 28-03-2018 CU254_RS01395 d6e43c4c9774cbd47a8dbf3845a1fec0 635 Pfam PF00361 Proton-conducting membrane transporter 132 421 3.5E-82 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS01395 d6e43c4c9774cbd47a8dbf3845a1fec0 635 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 262 284 9.1E-12 T 28-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CU254_RS01395 d6e43c4c9774cbd47a8dbf3845a1fec0 635 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 56 80 9.1E-12 T 28-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CU254_RS01395 d6e43c4c9774cbd47a8dbf3845a1fec0 635 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 82 102 9.1E-12 T 28-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CU254_RS01395 d6e43c4c9774cbd47a8dbf3845a1fec0 635 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 418 440 9.1E-12 T 28-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CU254_RS01395 d6e43c4c9774cbd47a8dbf3845a1fec0 635 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 62 119 7.4E-24 T 28-03-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS07170 bfdcdad23bc982a2f7c2ffbd068f4edf 1624 Gene3D G3DSA:1.10.287.850 77 165 9.6E-10 T 28-03-2018 CU254_RS07170 bfdcdad23bc982a2f7c2ffbd068f4edf 1624 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 743 780 3.9E-9 T 28-03-2018 IPR006530 YD repeat CU254_RS07170 bfdcdad23bc982a2f7c2ffbd068f4edf 1624 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 618 656 7.4E-7 T 28-03-2018 IPR006530 YD repeat CU254_RS07170 bfdcdad23bc982a2f7c2ffbd068f4edf 1624 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 889 919 7.0E-4 T 28-03-2018 IPR006530 YD repeat CU254_RS07170 bfdcdad23bc982a2f7c2ffbd068f4edf 1624 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 847 887 1.0E-9 T 28-03-2018 IPR006530 YD repeat CU254_RS07170 bfdcdad23bc982a2f7c2ffbd068f4edf 1624 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 700 737 9.2E-10 T 28-03-2018 IPR006530 YD repeat CU254_RS07170 bfdcdad23bc982a2f7c2ffbd068f4edf 1624 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1132 1163 4.4E-4 T 28-03-2018 IPR006530 YD repeat CU254_RS07170 bfdcdad23bc982a2f7c2ffbd068f4edf 1624 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 533 566 1.4E-6 T 28-03-2018 IPR006530 YD repeat CU254_RS07170 bfdcdad23bc982a2f7c2ffbd068f4edf 1624 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1164 1195 7.4E-7 T 28-03-2018 IPR006530 YD repeat CU254_RS07170 bfdcdad23bc982a2f7c2ffbd068f4edf 1624 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1291 1363 2.9E-22 T 28-03-2018 IPR022385 Rhs repeat-associated core GO:0097264 CU254_RS07170 bfdcdad23bc982a2f7c2ffbd068f4edf 1624 Pfam PF05593 RHS Repeat 700 737 1.6E-9 T 28-03-2018 IPR031325 RHS repeat CU254_RS07170 bfdcdad23bc982a2f7c2ffbd068f4edf 1624 Pfam PF05593 RHS Repeat 889 919 7.5E-5 T 28-03-2018 IPR031325 RHS repeat CU254_RS07170 bfdcdad23bc982a2f7c2ffbd068f4edf 1624 Pfam PF05593 RHS Repeat 847 882 8.4E-8 T 28-03-2018 IPR031325 RHS repeat CU254_RS07170 bfdcdad23bc982a2f7c2ffbd068f4edf 1624 Pfam PF05593 RHS Repeat 743 779 3.5E-8 T 28-03-2018 IPR031325 RHS repeat CU254_RS07170 bfdcdad23bc982a2f7c2ffbd068f4edf 1624 Pfam PF05593 RHS Repeat 534 567 4.6E-5 T 28-03-2018 IPR031325 RHS repeat CU254_RS07170 bfdcdad23bc982a2f7c2ffbd068f4edf 1624 Pfam PF05593 RHS Repeat 637 674 5.4E-9 T 28-03-2018 IPR031325 RHS repeat CU254_RS07170 bfdcdad23bc982a2f7c2ffbd068f4edf 1624 Pfam PF05593 RHS Repeat 552 586 7.0E-6 T 28-03-2018 IPR031325 RHS repeat CU254_RS27555 297d08dea3bd80ac5cbc998d0647980a 298 Pfam PF00487 Fatty acid desaturase 38 253 1.7E-19 T 28-03-2018 IPR005804 Fatty acid desaturase domain GO:0006629 CU254_RS27555 297d08dea3bd80ac5cbc998d0647980a 298 PRINTS PR00075 Fatty acid desaturase family 1 signature 38 60 5.7E-18 T 28-03-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 CU254_RS27555 297d08dea3bd80ac5cbc998d0647980a 298 PRINTS PR00075 Fatty acid desaturase family 1 signature 198 219 5.7E-18 T 28-03-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 CU254_RS27555 297d08dea3bd80ac5cbc998d0647980a 298 PRINTS PR00075 Fatty acid desaturase family 1 signature 241 255 5.7E-18 T 28-03-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 CU254_RS27555 297d08dea3bd80ac5cbc998d0647980a 298 PRINTS PR00075 Fatty acid desaturase family 1 signature 61 81 5.7E-18 T 28-03-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 CU254_RS37965 b9ff788165ec9da97c7a1ddb372b99bb 419 Gene3D G3DSA:1.20.1250.20 6 207 4.8E-12 T 28-03-2018 CU254_RS37965 b9ff788165ec9da97c7a1ddb372b99bb 419 Pfam PF05977 Transmembrane secretion effector 18 391 1.5E-9 T 28-03-2018 IPR010290 Transmembrane secretion effector CU254_RS37965 b9ff788165ec9da97c7a1ddb372b99bb 419 SUPERFAMILY SSF103473 19 399 2.22E-29 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS37965 b9ff788165ec9da97c7a1ddb372b99bb 419 PRINTS PR01988 Putative bacilysin exporter bacE signature 84 102 3.6E-6 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CU254_RS37965 b9ff788165ec9da97c7a1ddb372b99bb 419 PRINTS PR01988 Putative bacilysin exporter bacE signature 173 190 3.6E-6 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CU254_RS37965 b9ff788165ec9da97c7a1ddb372b99bb 419 PRINTS PR01988 Putative bacilysin exporter bacE signature 146 167 3.6E-6 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CU254_RS37965 b9ff788165ec9da97c7a1ddb372b99bb 419 PRINTS PR01988 Putative bacilysin exporter bacE signature 21 43 3.6E-6 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CU254_RS37965 b9ff788165ec9da97c7a1ddb372b99bb 419 Gene3D G3DSA:1.20.1250.20 216 410 1.9E-12 T 28-03-2018 CU254_RS20825 e353cae90842d54af82dc1916ce6b827 109 Gene3D G3DSA:1.10.10.10 2 98 1.7E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS20825 e353cae90842d54af82dc1916ce6b827 109 Pfam PF13601 Winged helix DNA-binding domain 15 93 4.2E-21 T 28-03-2018 IPR027395 Winged helix DNA-binding domain CU254_RS20825 e353cae90842d54af82dc1916ce6b827 109 SUPERFAMILY SSF46785 4 94 3.56E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS01535 6bb107235c97ca2eb5ea826f0e4f2509 257 Pfam PF01569 PAP2 superfamily 168 241 3.7E-15 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CU254_RS01535 6bb107235c97ca2eb5ea826f0e4f2509 257 SMART SM00014 133 241 4.0E-8 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CU254_RS01535 6bb107235c97ca2eb5ea826f0e4f2509 257 Gene3D G3DSA:1.20.144.10 45 253 2.1E-16 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CU254_RS01535 6bb107235c97ca2eb5ea826f0e4f2509 257 SUPERFAMILY SSF48317 54 246 3.79E-27 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CU254_RS23190 8a3a83ef7b3d938af36ba5d1d8a5ab2d 61 SUPERFAMILY SSF69047 5 59 2.22E-9 T 28-03-2018 IPR008462 CsbD-like domain CU254_RS23190 8a3a83ef7b3d938af36ba5d1d8a5ab2d 61 Gene3D G3DSA:1.10.1470.10 3 61 6.8E-17 T 28-03-2018 IPR008462 CsbD-like domain CU254_RS23190 8a3a83ef7b3d938af36ba5d1d8a5ab2d 61 Pfam PF05532 CsbD-like 5 56 4.8E-18 T 28-03-2018 IPR008462 CsbD-like domain CU254_RS26260 3591ffd76fd69ed69c5dde76ebd53f66 857 SUPERFAMILY SSF52540 18 162 2.09E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS26260 3591ffd76fd69ed69c5dde76ebd53f66 857 SMART SM00491 348 476 3.8E-4 T 28-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CU254_RS26260 3591ffd76fd69ed69c5dde76ebd53f66 857 SMART SM00487 32 325 4.5E-7 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CU254_RS26260 3591ffd76fd69ed69c5dde76ebd53f66 857 Gene3D G3DSA:3.40.50.300 330 693 0.22 T 28-03-2018 CU254_RS26260 3591ffd76fd69ed69c5dde76ebd53f66 857 Gene3D G3DSA:3.40.50.300 16 301 7.1E-17 T 28-03-2018 CU254_RS26260 3591ffd76fd69ed69c5dde76ebd53f66 857 SUPERFAMILY SSF52540 281 470 9.5E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS26260 3591ffd76fd69ed69c5dde76ebd53f66 857 SUPERFAMILY SSF52540 46 180 9.5E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS06775 3e83bc1c1063ed7b906f73a90e6ef171 344 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 11 333 5.3E-18 T 28-03-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CU254_RS06775 3e83bc1c1063ed7b906f73a90e6ef171 344 SUPERFAMILY SSF51726 50 334 3.14E-21 T 28-03-2018 CU254_RS06775 3e83bc1c1063ed7b906f73a90e6ef171 344 Gene3D G3DSA:3.20.20.210 45 341 6.1E-39 T 28-03-2018 CU254_RS04160 f50fd4098049895441703b8e2676a016 506 Pfam PF09972 Predicted membrane protein (DUF2207) 31 454 3.2E-28 T 28-03-2018 IPR018702 Protein of unknown function DUF2207, membrane CU254_RS27015 bc653dac6e978e1acf2f3c22d05b75f7 309 Pfam PF00756 Putative esterase 75 244 8.5E-9 T 28-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 CU254_RS27015 bc653dac6e978e1acf2f3c22d05b75f7 309 Gene3D G3DSA:3.40.50.1820 61 309 3.2E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS27015 bc653dac6e978e1acf2f3c22d05b75f7 309 SUPERFAMILY SSF53474 66 306 4.84E-24 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS36190 6bfc0a341d86cb63934ecafeb6949c8e 340 Pfam PF04909 Amidohydrolase 44 329 4.4E-32 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CU254_RS36190 6bfc0a341d86cb63934ecafeb6949c8e 340 Gene3D G3DSA:3.20.20.140 5 331 1.3E-55 T 28-03-2018 CU254_RS36190 6bfc0a341d86cb63934ecafeb6949c8e 340 SUPERFAMILY SSF51556 16 330 2.19E-67 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS35675 42c28dd6eb4d8dfcab9e23e22526ba53 213 Gene3D G3DSA:3.40.430.10 5 210 3.7E-35 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CU254_RS35675 42c28dd6eb4d8dfcab9e23e22526ba53 213 SUPERFAMILY SSF53597 68 211 6.02E-24 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CU254_RS35675 42c28dd6eb4d8dfcab9e23e22526ba53 213 Pfam PF01872 RibD C-terminal domain 10 189 1.2E-13 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CU254_RS01210 e50f41855664ea5bc434e5bbbba18cad 208 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 6 188 7.5E-35 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CU254_RS01210 e50f41855664ea5bc434e5bbbba18cad 208 Gene3D G3DSA:3.40.50.1240 1 201 2.2E-29 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CU254_RS01210 e50f41855664ea5bc434e5bbbba18cad 208 SUPERFAMILY SSF53254 3 193 6.33E-36 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CU254_RS01210 e50f41855664ea5bc434e5bbbba18cad 208 SMART SM00855 4 156 7.4E-16 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CU254_RS07410 bc1295504decd13a8204d6eed26af17c 457 SUPERFAMILY SSF143548 17 157 1.07E-46 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CU254_RS07410 bc1295504decd13a8204d6eed26af17c 457 Gene3D G3DSA:3.30.1330.90 11 160 4.5E-56 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CU254_RS07410 bc1295504decd13a8204d6eed26af17c 457 TIGRFAM TIGR00720 sda_mono: L-serine ammonia-lyase 3 454 5.8E-207 T 28-03-2018 IPR004644 Iron-sulphur-dependent L-serine dehydratase single chain form GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CU254_RS07410 bc1295504decd13a8204d6eed26af17c 457 Gene3D G3DSA:1.10.4100.10 265 445 4.4E-32 T 28-03-2018 CU254_RS07410 bc1295504decd13a8204d6eed26af17c 457 Pfam PF03313 Serine dehydratase alpha chain 188 451 7.5E-103 T 28-03-2018 IPR005130 Serine dehydratase-like, alpha subunit CU254_RS07410 bc1295504decd13a8204d6eed26af17c 457 Pfam PF03315 Serine dehydratase beta chain 4 156 5.1E-59 T 28-03-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CU254_RS10605 ead25858275ef8b89261b1a0184ec6d8 153 SMART SM00347 28 128 1.3E-17 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS10605 ead25858275ef8b89261b1a0184ec6d8 153 SUPERFAMILY SSF46785 9 144 5.37E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS10605 ead25858275ef8b89261b1a0184ec6d8 153 Pfam PF12802 MarR family 34 92 4.2E-10 T 28-03-2018 CU254_RS10605 ead25858275ef8b89261b1a0184ec6d8 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 84 5.3E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS10605 ead25858275ef8b89261b1a0184ec6d8 153 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 104 5.3E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS10605 ead25858275ef8b89261b1a0184ec6d8 153 Gene3D G3DSA:1.10.10.10 1 149 5.3E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS27160 7368dfadec123e27c67a910aec457f95 156 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 14 152 1.4E-26 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CU254_RS27160 7368dfadec123e27c67a910aec457f95 156 Gene3D G3DSA:3.30.530.20 2 156 2.4E-26 T 28-03-2018 IPR023393 START-like domain CU254_RS27160 7368dfadec123e27c67a910aec457f95 156 SUPERFAMILY SSF55961 3 154 1.38E-37 T 28-03-2018 CU254_RS15345 35b4b158c1250c67e4fa8d422b9c1d11 366 SUPERFAMILY SSF51604 100 364 1.9E-55 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CU254_RS15345 35b4b158c1250c67e4fa8d422b9c1d11 366 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 18 112 2.8E-6 T 28-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CU254_RS15345 35b4b158c1250c67e4fa8d422b9c1d11 366 SMART SM00922 130 237 1.3E-15 T 28-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CU254_RS15345 35b4b158c1250c67e4fa8d422b9c1d11 366 SUPERFAMILY SSF54826 2 113 1.71E-17 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CU254_RS15345 35b4b158c1250c67e4fa8d422b9c1d11 366 Gene3D G3DSA:3.30.390.10 1 115 6.2E-22 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CU254_RS15345 35b4b158c1250c67e4fa8d422b9c1d11 366 Gene3D G3DSA:3.20.20.120 116 358 1.4E-49 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CU254_RS15345 35b4b158c1250c67e4fa8d422b9c1d11 366 Pfam PF13378 Enolase C-terminal domain-like 134 360 2.1E-53 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CU254_RS28630 4135cbb1c63d7e0781f881a3ba114e18 308 SMART SM00478 140 298 7.3E-4 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CU254_RS28630 4135cbb1c63d7e0781f881a3ba114e18 308 Gene3D G3DSA:1.10.1670.10 260 301 1.8E-4 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CU254_RS28630 4135cbb1c63d7e0781f881a3ba114e18 308 SUPERFAMILY SSF48150 121 293 7.33E-26 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CU254_RS28630 4135cbb1c63d7e0781f881a3ba114e18 308 Gene3D G3DSA:1.10.340.30 102 259 5.7E-21 T 28-03-2018 CU254_RS12975 d9bad1f39774df4a7f3a38c9f966762f 420 Pfam PF05977 Transmembrane secretion effector 13 405 1.2E-27 T 28-03-2018 IPR010290 Transmembrane secretion effector CU254_RS12975 d9bad1f39774df4a7f3a38c9f966762f 420 SUPERFAMILY SSF103473 22 409 2.62E-40 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS12975 d9bad1f39774df4a7f3a38c9f966762f 420 Gene3D G3DSA:1.20.1250.20 214 413 4.3E-18 T 28-03-2018 CU254_RS12975 d9bad1f39774df4a7f3a38c9f966762f 420 Gene3D G3DSA:1.20.1250.20 9 210 3.8E-22 T 28-03-2018 CU254_RS00685 230ee5445e9b92cb419455acbc34ea71 446 Pfam PF00860 Permease family 17 394 7.1E-95 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CU254_RS00685 230ee5445e9b92cb419455acbc34ea71 446 TIGRFAM TIGR03173 pbuX: xanthine permease 20 434 7.7E-138 T 28-03-2018 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 CU254_RS00685 230ee5445e9b92cb419455acbc34ea71 446 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 343 363 - T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CU254_RS00685 230ee5445e9b92cb419455acbc34ea71 446 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 15 432 2.8E-99 T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CU254_RS19080 0b06c7f6a9ab5e3e8e44c7f287f14712 260 Pfam PF04199 Putative cyclase 5 185 5.9E-35 T 28-03-2018 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 CU254_RS19080 0b06c7f6a9ab5e3e8e44c7f287f14712 260 SUPERFAMILY SSF102198 2 255 6.02E-54 T 28-03-2018 CU254_RS19080 0b06c7f6a9ab5e3e8e44c7f287f14712 260 Gene3D G3DSA:3.50.30.50 1 258 4.2E-54 T 28-03-2018 CU254_RS28330 65a9748a744e9d6a5758e1c7dae5be4e 323 Pfam PF01008 Initiation factor 2 subunit family 45 319 1.5E-62 T 28-03-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 CU254_RS28330 65a9748a744e9d6a5758e1c7dae5be4e 323 Gene3D G3DSA:3.40.50.10470 126 321 7.6E-61 T 28-03-2018 CU254_RS28330 65a9748a744e9d6a5758e1c7dae5be4e 323 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 3 319 2.0E-114 T 28-03-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 CU254_RS28330 65a9748a744e9d6a5758e1c7dae5be4e 323 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 1 322 34.992 T 28-03-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 CU254_RS28330 65a9748a744e9d6a5758e1c7dae5be4e 323 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 30 319 1.8E-89 T 28-03-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 CU254_RS28330 65a9748a744e9d6a5758e1c7dae5be4e 323 Gene3D G3DSA:1.20.120.420 3 125 2.2E-33 T 28-03-2018 IPR027363 Methylthioribose-1-phosphate isomerase-like, N-terminal domain KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 CU254_RS28330 65a9748a744e9d6a5758e1c7dae5be4e 323 SUPERFAMILY SSF100950 3 319 2.09E-98 T 28-03-2018 CU254_RS20625 a809091587ecc6d57001f6403d8045f8 356 Gene3D G3DSA:3.90.1150.10 255 356 2.0E-5 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS20625 a809091587ecc6d57001f6403d8045f8 356 SUPERFAMILY SSF53383 4 355 3.85E-50 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS20625 a809091587ecc6d57001f6403d8045f8 356 Pfam PF00266 Aminotransferase class-V 57 297 1.2E-17 T 28-03-2018 IPR000192 Aminotransferase class V domain CU254_RS20625 a809091587ecc6d57001f6403d8045f8 356 Gene3D G3DSA:3.40.640.10 28 254 5.7E-25 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS28640 894d2e87c2c5a725bf79651b54d2a964 440 Gene3D G3DSA:3.40.630.10 16 296 1.3E-48 T 28-03-2018 CU254_RS28640 894d2e87c2c5a725bf79651b54d2a964 440 SUPERFAMILY SSF53187 320 417 3.1E-53 T 28-03-2018 CU254_RS28640 894d2e87c2c5a725bf79651b54d2a964 440 SUPERFAMILY SSF53187 47 219 3.1E-53 T 28-03-2018 CU254_RS28640 894d2e87c2c5a725bf79651b54d2a964 440 Pfam PF07687 Peptidase dimerisation domain 207 296 5.0E-9 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CU254_RS28640 894d2e87c2c5a725bf79651b54d2a964 440 PIRSF PIRSF037226 37 433 1.8E-123 T 28-03-2018 IPR017144 Peptidase M20A, amidohydrolase, predicted CU254_RS28640 894d2e87c2c5a725bf79651b54d2a964 440 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 58 385 3.1E-71 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CU254_RS28640 894d2e87c2c5a725bf79651b54d2a964 440 Gene3D G3DSA:3.40.630.10 297 432 2.8E-15 T 28-03-2018 CU254_RS28640 894d2e87c2c5a725bf79651b54d2a964 440 SUPERFAMILY SSF55031 204 312 9.68E-24 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CU254_RS04140 09d166859c12981de0bcd3b22077392a 426 Gene3D G3DSA:2.60.40.10 54 154 8.4E-5 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS04140 09d166859c12981de0bcd3b22077392a 426 Pfam PF01882 Protein of unknown function DUF58 186 271 3.5E-21 T 28-03-2018 IPR002881 Domain of unknown function DUF58 CU254_RS04140 09d166859c12981de0bcd3b22077392a 426 Pfam PF01345 Domain of unknown function DUF11 59 125 5.7E-7 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CU254_RS04140 09d166859c12981de0bcd3b22077392a 426 Gene3D G3DSA:3.40.50.410 198 405 5.0E-21 T 28-03-2018 IPR002035 von Willebrand factor, type A CU254_RS22680 9ebfcc004dc21ac0719c648b5817d1d8 470 Gene3D G3DSA:3.40.50.1820 1 470 2.4E-118 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS22680 9ebfcc004dc21ac0719c648b5817d1d8 470 ProSitePatterns PS00941 Carboxylesterases type-B signature 2. 73 83 - T 28-03-2018 IPR019819 Carboxylesterase type B, conserved site CU254_RS22680 9ebfcc004dc21ac0719c648b5817d1d8 470 SUPERFAMILY SSF53474 3 470 1.2E-107 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS22680 9ebfcc004dc21ac0719c648b5817d1d8 470 Pfam PF00135 Carboxylesterase family 2 444 2.3E-91 T 28-03-2018 IPR002018 Carboxylesterase, type B CU254_RS36320 475221747078ced2906f6b85858058cb 268 SUPERFAMILY SSF51717 1 262 3.92E-92 T 28-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CU254_RS36320 475221747078ced2906f6b85858058cb 268 Pfam PF00809 Pterin binding enzyme 1 246 1.4E-88 T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CU254_RS36320 475221747078ced2906f6b85858058cb 268 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 1 260 2.6E-92 T 28-03-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 CU254_RS36320 475221747078ced2906f6b85858058cb 268 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 34 47 - T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CU254_RS36320 475221747078ced2906f6b85858058cb 268 Gene3D G3DSA:3.20.20.20 134 266 1.6E-44 T 28-03-2018 CU254_RS36320 475221747078ced2906f6b85858058cb 268 Gene3D G3DSA:3.20.20.20 1 133 1.9E-58 T 28-03-2018 CU254_RS31915 8ddd674540bce7f424143c23d08f9f5a 225 Gene3D G3DSA:1.10.10.10 1 71 3.7E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS31915 8ddd674540bce7f424143c23d08f9f5a 225 SMART SM00345 16 74 1.9E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS31915 8ddd674540bce7f424143c23d08f9f5a 225 SUPERFAMILY SSF46785 9 78 6.42E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS31915 8ddd674540bce7f424143c23d08f9f5a 225 Pfam PF07729 FCD domain 86 207 1.2E-23 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS31915 8ddd674540bce7f424143c23d08f9f5a 225 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 74 1.0E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS31915 8ddd674540bce7f424143c23d08f9f5a 225 Gene3D G3DSA:1.20.120.530 72 225 2.9E-26 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS31915 8ddd674540bce7f424143c23d08f9f5a 225 SMART SM00895 84 210 1.6E-12 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS31915 8ddd674540bce7f424143c23d08f9f5a 225 SUPERFAMILY SSF48008 85 215 5.49E-19 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS22320 2611090b1cf068ec261aef099e7b3ed8 428 Gene3D G3DSA:3.65.10.10 235 426 2.9E-48 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CU254_RS22320 2611090b1cf068ec261aef099e7b3ed8 428 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 15 423 1.2E-107 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CU254_RS22320 2611090b1cf068ec261aef099e7b3ed8 428 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 16 428 28.787 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CU254_RS22320 2611090b1cf068ec261aef099e7b3ed8 428 ProSitePatterns PS00885 EPSP synthase signature 2. 342 360 - T 28-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CU254_RS22320 2611090b1cf068ec261aef099e7b3ed8 428 PIRSF PIRSF000505 7 428 7.9E-116 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CU254_RS22320 2611090b1cf068ec261aef099e7b3ed8 428 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 21 424 1.7E-114 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CU254_RS22320 2611090b1cf068ec261aef099e7b3ed8 428 SUPERFAMILY SSF55205 14 424 5.89E-105 T 28-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CU254_RS22320 2611090b1cf068ec261aef099e7b3ed8 428 Gene3D G3DSA:3.65.10.10 28 234 9.9E-55 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CU254_RS05410 90c22b4d31811d5598601429b61fa1d6 230 Gene3D G3DSA:3.40.50.1820 2 230 3.4E-31 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS05410 90c22b4d31811d5598601429b61fa1d6 230 Pfam PF12697 Alpha/beta hydrolase family 5 222 5.5E-20 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS05410 90c22b4d31811d5598601429b61fa1d6 230 SUPERFAMILY SSF53474 4 226 3.38E-33 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS12500 98601c11f3c34977fd0575ae430890fd 391 SMART SM00387 296 390 1.3E-4 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS12500 98601c11f3c34977fd0575ae430890fd 391 SUPERFAMILY SSF55874 265 387 8.21E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS12500 98601c11f3c34977fd0575ae430890fd 391 PIRSF PIRSF037434 1 391 1.6E-131 T 28-03-2018 IPR017205 Signal transduction histidine kinase, ChrS CU254_RS12500 98601c11f3c34977fd0575ae430890fd 391 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 298 388 7.7E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS12500 98601c11f3c34977fd0575ae430890fd 391 Gene3D G3DSA:3.30.565.10 155 389 2.0E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS12500 98601c11f3c34977fd0575ae430890fd 391 Pfam PF07730 Histidine kinase 191 257 8.8E-18 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CU254_RS12500 98601c11f3c34977fd0575ae430890fd 391 PRINTS PR00344 Bacterial sensor protein C-terminal signature 350 368 9.0E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS12500 98601c11f3c34977fd0575ae430890fd 391 PRINTS PR00344 Bacterial sensor protein C-terminal signature 374 387 9.0E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS12500 98601c11f3c34977fd0575ae430890fd 391 PRINTS PR00344 Bacterial sensor protein C-terminal signature 332 346 9.0E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS40250 672e7bd335406eecffcc1995650e615f 368 SUPERFAMILY SSF53383 12 367 2.53E-108 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS40250 672e7bd335406eecffcc1995650e615f 368 Gene3D G3DSA:3.40.640.10 211 230 0.12 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS40250 672e7bd335406eecffcc1995650e615f 368 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 12 363 1.8E-119 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CU254_RS40250 672e7bd335406eecffcc1995650e615f 368 PIRSF PIRSF000390 1 368 4.8E-110 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CU254_RS40250 672e7bd335406eecffcc1995650e615f 368 Gene3D G3DSA:3.40.640.10 8 210 2.1E-45 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS40250 672e7bd335406eecffcc1995650e615f 368 Gene3D G3DSA:3.90.1150.10 231 368 2.1E-40 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS14620 124395a491f4472581c20563b72c1a0a 101 Gene3D G3DSA:3.10.20.30 3 101 1.3E-8 T 28-03-2018 IPR012675 Beta-grasp domain CU254_RS29205 bcf5ab73f88c624905a6b84d130f259f 435 SUPERFAMILY SSF51556 126 415 5.17E-50 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS29205 bcf5ab73f88c624905a6b84d130f259f 435 SUPERFAMILY SSF51556 57 85 5.17E-50 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS29205 bcf5ab73f88c624905a6b84d130f259f 435 Gene3D G3DSA:3.20.20.140 53 418 1.0E-40 T 28-03-2018 CU254_RS29205 bcf5ab73f88c624905a6b84d130f259f 435 Pfam PF04909 Amidohydrolase 142 415 3.9E-18 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CU254_RS18140 6f80393224ed7a8f64ea74e45950decf 303 Pfam PF09754 PAC2 family 30 248 3.1E-54 T 28-03-2018 IPR019151 Proteasome assembly chaperone 2 CU254_RS18140 6f80393224ed7a8f64ea74e45950decf 303 Gene3D G3DSA:1.10.287.100 229 269 3.0E-12 T 28-03-2018 CU254_RS18140 6f80393224ed7a8f64ea74e45950decf 303 PIRSF PIRSF028754 10 300 1.0E-110 T 28-03-2018 IPR008492 Protein of unknown function DUF774 CU254_RS18140 6f80393224ed7a8f64ea74e45950decf 303 SUPERFAMILY SSF159659 17 269 2.22E-91 T 28-03-2018 CU254_RS39250 daf83e33d7022e5f4625117a889aa535 384 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 384 92.974 T 28-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 CU254_RS39250 daf83e33d7022e5f4625117a889aa535 384 ProSitePatterns PS00618 RecF protein signature 2. 327 345 - T 28-03-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 CU254_RS39250 daf83e33d7022e5f4625117a889aa535 384 SUPERFAMILY SSF52540 255 348 5.55E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS39250 daf83e33d7022e5f4625117a889aa535 384 SUPERFAMILY SSF52540 2 215 5.55E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS39250 daf83e33d7022e5f4625117a889aa535 384 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 2 378 7.9E-113 T 28-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 CU254_RS39250 daf83e33d7022e5f4625117a889aa535 384 ProSitePatterns PS00617 RecF protein signature 1. 117 137 - T 28-03-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 CU254_RS39250 daf83e33d7022e5f4625117a889aa535 384 Gene3D G3DSA:3.40.50.300 2 375 5.0E-25 T 28-03-2018 CU254_RS39250 daf83e33d7022e5f4625117a889aa535 384 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 359 2.0E-15 T 28-03-2018 IPR003395 RecF/RecN/SMC, N-terminal CU254_RS32565 9dc79f297bd5a0f6a3f9836d977b2cef 361 Gene3D G3DSA:3.40.50.10490 197 348 1.2E-25 T 28-03-2018 CU254_RS32565 9dc79f297bd5a0f6a3f9836d977b2cef 361 SUPERFAMILY SSF53697 63 348 8.23E-41 T 28-03-2018 CU254_RS06135 45b273ed26bb71e38238210ddb779208 341 Pfam PF02547 Queuosine biosynthesis protein 7 338 1.7E-73 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CU254_RS06135 45b273ed26bb71e38238210ddb779208 341 SUPERFAMILY SSF111337 7 338 1.96E-74 T 28-03-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 CU254_RS06135 45b273ed26bb71e38238210ddb779208 341 Gene3D G3DSA:3.40.1780.10 1 95 9.1E-12 T 28-03-2018 CU254_RS06135 45b273ed26bb71e38238210ddb779208 341 Gene3D G3DSA:3.40.1780.10 180 339 3.3E-43 T 28-03-2018 CU254_RS35280 9214b3b380d28a91004c34216d6f2304 258 Pfam PF05331 Protein of unknown function (DUF742) 146 257 5.6E-31 T 28-03-2018 IPR007995 Protein of unknown function DUF742 CU254_RS04320 289466392b44937109677b8bfbec81da 332 Pfam PF00877 NlpC/P60 family 222 311 2.1E-23 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CU254_RS04320 289466392b44937109677b8bfbec81da 332 Gene3D G3DSA:3.90.1720.10 202 328 7.3E-33 T 28-03-2018 CU254_RS04320 289466392b44937109677b8bfbec81da 332 SUPERFAMILY SSF54001 203 317 4.9E-34 T 28-03-2018 CU254_RS36585 bc349ed012831105a5d3e6d28438f25c 150 Pfam PF02627 Carboxymuconolactone decarboxylase family 13 94 2.5E-19 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CU254_RS36585 bc349ed012831105a5d3e6d28438f25c 150 Gene3D G3DSA:1.20.1290.10 1 149 1.0E-36 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CU254_RS36585 bc349ed012831105a5d3e6d28438f25c 150 SUPERFAMILY SSF69118 10 148 1.66E-42 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CU254_RS36585 bc349ed012831105a5d3e6d28438f25c 150 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 31 79 2.0E-13 T 28-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CU254_RS03445 295a2478b74a96b03b8192a76bc539a8 480 Gene3D G3DSA:1.20.120.20 2 409 5.2E-4 T 28-03-2018 CU254_RS03055 15d6012ec88f6b39c1d335dc6da9d229 634 Pfam PF13382 Adenine deaminase C-terminal domain 480 612 1.8E-19 T 28-03-2018 IPR026912 Adenine deaminase C-terminal domain KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 CU254_RS03055 15d6012ec88f6b39c1d335dc6da9d229 634 Pfam PF01979 Amidohydrolase family 357 413 1.6E-7 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CU254_RS03055 15d6012ec88f6b39c1d335dc6da9d229 634 SUPERFAMILY SSF51338 384 418 1.98E-13 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS03055 15d6012ec88f6b39c1d335dc6da9d229 634 SUPERFAMILY SSF51338 77 139 1.98E-13 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS03055 15d6012ec88f6b39c1d335dc6da9d229 634 Gene3D G3DSA:2.30.40.10 321 424 2.2E-16 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS03055 15d6012ec88f6b39c1d335dc6da9d229 634 Gene3D G3DSA:2.30.40.10 81 143 4.1E-13 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS03055 15d6012ec88f6b39c1d335dc6da9d229 634 Gene3D G3DSA:3.20.20.140 144 264 3.4E-6 T 28-03-2018 CU254_RS03055 15d6012ec88f6b39c1d335dc6da9d229 634 SUPERFAMILY SSF51556 139 379 1.08E-10 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS37565 a9517ecb9bb5f5075f2ec6f98b9068d5 359 Pfam PF02361 Cobalt transport protein 4 221 2.6E-12 T 28-03-2018 IPR003339 ABC/ECF transporter, transmembrane component CU254_RS16315 0bfb6fd64d200554e341536abb86b275 260 Pfam PF08241 Methyltransferase domain 46 136 5.8E-12 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CU254_RS16315 0bfb6fd64d200554e341536abb86b275 260 SUPERFAMILY SSF53335 17 141 9.69E-25 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS16315 0bfb6fd64d200554e341536abb86b275 260 Gene3D G3DSA:3.40.50.150 2 245 5.5E-27 T 28-03-2018 CU254_RS06055 2182963854c94eb133314f0ee4f625cb 340 SUPERFAMILY SSF48576 28 339 5.76E-79 T 28-03-2018 IPR008949 Isoprenoid synthase domain CU254_RS06055 2182963854c94eb133314f0ee4f625cb 340 Gene3D G3DSA:1.10.600.10 1 340 3.6E-93 T 28-03-2018 IPR008949 Isoprenoid synthase domain CU254_RS06055 2182963854c94eb133314f0ee4f625cb 340 Pfam PF00348 Polyprenyl synthetase 52 280 4.4E-57 T 28-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 CU254_RS06055 2182963854c94eb133314f0ee4f625cb 340 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 99 113 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site CU254_RS29520 117e55bca3ef8a49339f314c122a4016 154 Pfam PF13280 WYL domain 28 147 3.7E-9 T 28-03-2018 IPR026881 WYL domain CU254_RS19585 c03f5c6e53a5026772f6e7bc44ade3e9 353 Gene3D G3DSA:3.40.50.720 1 136 3.3E-37 T 28-03-2018 CU254_RS19585 c03f5c6e53a5026772f6e7bc44ade3e9 353 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 7 127 6.5E-21 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CU254_RS19585 c03f5c6e53a5026772f6e7bc44ade3e9 353 SUPERFAMILY SSF51735 2 159 2.92E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS19585 c03f5c6e53a5026772f6e7bc44ade3e9 353 Gene3D G3DSA:3.30.360.10 137 353 2.5E-26 T 28-03-2018 CU254_RS19585 c03f5c6e53a5026772f6e7bc44ade3e9 353 SUPERFAMILY SSF55347 133 308 2.29E-19 T 28-03-2018 CU254_RS15550 c31933b2a43bc6b0f4a9647ec2eb89fd 378 Gene3D G3DSA:3.90.1150.10 274 377 5.9E-6 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS15550 c31933b2a43bc6b0f4a9647ec2eb89fd 378 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 228 237 - T 28-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 CU254_RS15550 c31933b2a43bc6b0f4a9647ec2eb89fd 378 SUPERFAMILY SSF53383 32 366 2.02E-78 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS15550 c31933b2a43bc6b0f4a9647ec2eb89fd 378 Pfam PF00155 Aminotransferase class I and II 35 359 5.5E-46 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CU254_RS15550 c31933b2a43bc6b0f4a9647ec2eb89fd 378 Gene3D G3DSA:3.40.640.10 39 273 2.9E-44 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS41395 08c0c2b9de7289807e5fe381c3b1bc18 222 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 50 198 5.2E-10 T 28-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal CU254_RS37205 cac21f59787a75dab4a1eb2eb409be09 297 PIRSF PIRSF000654 22 260 3.6E-21 T 28-03-2018 CU254_RS37205 cac21f59787a75dab4a1eb2eb409be09 297 Gene3D G3DSA:1.10.510.10 90 261 3.3E-48 T 28-03-2018 CU254_RS37205 cac21f59787a75dab4a1eb2eb409be09 297 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 14 37 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 CU254_RS37205 cac21f59787a75dab4a1eb2eb409be09 297 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 126 138 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CU254_RS37205 cac21f59787a75dab4a1eb2eb409be09 297 Gene3D G3DSA:3.30.200.20 2 89 7.9E-21 T 28-03-2018 CU254_RS37205 cac21f59787a75dab4a1eb2eb409be09 297 Pfam PF00069 Protein kinase domain 13 257 3.5E-48 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CU254_RS37205 cac21f59787a75dab4a1eb2eb409be09 297 SMART SM00220 7 262 4.2E-58 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CU254_RS37205 cac21f59787a75dab4a1eb2eb409be09 297 SUPERFAMILY SSF56112 4 269 3.99E-73 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS08520 e5803a858f51b2905e3f22118d7061e9 212 Pfam PF11774 Lsr2 1 75 1.2E-13 T 28-03-2018 IPR024412 Lsr2 CU254_RS08520 e5803a858f51b2905e3f22118d7061e9 212 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 1 60 2.0E-4 T 28-03-2018 IPR024412 Lsr2 CU254_RS20005 731c351e35de73058d1b28e66937e45d 494 PIRSF PIRSF006060 1 491 7.7E-64 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CU254_RS20005 731c351e35de73058d1b28e66937e45d 494 Pfam PF13520 Amino acid permease 22 432 6.7E-46 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CU254_RS11235 523c7ebd1e836170dbf952244734c019 375 SUPERFAMILY SSF56601 11 366 7.35E-55 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CU254_RS11235 523c7ebd1e836170dbf952244734c019 375 Pfam PF00144 Beta-lactamase 25 367 5.7E-52 T 28-03-2018 IPR001466 Beta-lactamase-related CU254_RS11235 523c7ebd1e836170dbf952244734c019 375 Gene3D G3DSA:3.40.710.10 2 375 1.8E-63 T 28-03-2018 CU254_RS13830 d8ff182cbfd82c31458c65decc2b7817 295 SUPERFAMILY SSF53850 89 277 4.16E-20 T 28-03-2018 CU254_RS13830 d8ff182cbfd82c31458c65decc2b7817 295 Gene3D G3DSA:3.40.190.10 86 171 2.5E-15 T 28-03-2018 CU254_RS13830 d8ff182cbfd82c31458c65decc2b7817 295 SUPERFAMILY SSF46785 4 85 7.19E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS13830 d8ff182cbfd82c31458c65decc2b7817 295 Pfam PF03466 LysR substrate binding domain 88 277 4.6E-21 T 28-03-2018 IPR005119 LysR, substrate-binding CU254_RS13830 d8ff182cbfd82c31458c65decc2b7817 295 Gene3D G3DSA:1.10.10.10 1 85 2.9E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS13830 d8ff182cbfd82c31458c65decc2b7817 295 Gene3D G3DSA:3.40.190.10 172 254 4.4E-9 T 28-03-2018 CU254_RS13830 d8ff182cbfd82c31458c65decc2b7817 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 6.7E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS13830 d8ff182cbfd82c31458c65decc2b7817 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 6.7E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS13830 d8ff182cbfd82c31458c65decc2b7817 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 6.7E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS13830 d8ff182cbfd82c31458c65decc2b7817 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 5.1E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS13370 5af81cd523b9e2c7929d084f0fc700c6 269 PRINTS PR00164 ABC-2 type transport system membrane protein signature 156 180 4.8E-7 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CU254_RS13370 5af81cd523b9e2c7929d084f0fc700c6 269 PRINTS PR00164 ABC-2 type transport system membrane protein signature 193 212 4.8E-7 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CU254_RS13370 5af81cd523b9e2c7929d084f0fc700c6 269 PRINTS PR00164 ABC-2 type transport system membrane protein signature 73 95 4.8E-7 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CU254_RS13370 5af81cd523b9e2c7929d084f0fc700c6 269 PRINTS PR00164 ABC-2 type transport system membrane protein signature 213 232 4.8E-7 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CU254_RS13370 5af81cd523b9e2c7929d084f0fc700c6 269 Pfam PF01061 ABC-2 type transporter 24 235 2.8E-36 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CU254_RS13370 5af81cd523b9e2c7929d084f0fc700c6 269 PIRSF PIRSF006648 6 269 2.8E-64 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CU254_RS39925 1083cf2002e6632d82606a2cc6778728 281 SUPERFAMILY SSF52096 170 230 4.62E-38 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS39925 1083cf2002e6632d82606a2cc6778728 281 SUPERFAMILY SSF52096 20 139 4.62E-38 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS39925 1083cf2002e6632d82606a2cc6778728 281 Pfam PF01343 Peptidase family S49 93 236 1.2E-35 T 28-03-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 CU254_RS39925 1083cf2002e6632d82606a2cc6778728 281 Gene3D G3DSA:3.90.226.10 16 251 3.7E-36 T 28-03-2018 CU254_RS15740 35a1b10dde3c32fab260ef275199ed8b 219 SUPERFAMILY SSF52499 26 215 7.72E-45 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CU254_RS15740 35a1b10dde3c32fab260ef275199ed8b 219 Gene3D G3DSA:3.40.50.850 11 219 1.6E-42 T 28-03-2018 CU254_RS15740 35a1b10dde3c32fab260ef275199ed8b 219 Pfam PF00857 Isochorismatase family 33 207 2.2E-36 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CU254_RS24685 0f29561dab98718ca89519160009d720 241 Pfam PF13489 Methyltransferase domain 17 193 1.9E-15 T 28-03-2018 CU254_RS24685 0f29561dab98718ca89519160009d720 241 SUPERFAMILY SSF53335 26 199 5.63E-27 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS24685 0f29561dab98718ca89519160009d720 241 Gene3D G3DSA:3.40.50.150 4 241 1.4E-28 T 28-03-2018 CU254_RS17870 641d3b50bef3c25645f297b91b5dc7e4 262 PRINTS PR00069 Aldo-keto reductase signature 37 61 4.0E-44 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CU254_RS17870 641d3b50bef3c25645f297b91b5dc7e4 262 PRINTS PR00069 Aldo-keto reductase signature 125 142 4.0E-44 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CU254_RS17870 641d3b50bef3c25645f297b91b5dc7e4 262 PRINTS PR00069 Aldo-keto reductase signature 159 188 4.0E-44 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CU254_RS17870 641d3b50bef3c25645f297b91b5dc7e4 262 PRINTS PR00069 Aldo-keto reductase signature 196 220 4.0E-44 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CU254_RS17870 641d3b50bef3c25645f297b91b5dc7e4 262 PRINTS PR00069 Aldo-keto reductase signature 93 111 4.0E-44 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CU254_RS17870 641d3b50bef3c25645f297b91b5dc7e4 262 SUPERFAMILY SSF51430 6 260 9.69E-95 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS17870 641d3b50bef3c25645f297b91b5dc7e4 262 PIRSF PIRSF000097 1 262 9.7E-82 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CU254_RS17870 641d3b50bef3c25645f297b91b5dc7e4 262 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 229 244 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CU254_RS17870 641d3b50bef3c25645f297b91b5dc7e4 262 Pfam PF00248 Aldo/keto reductase family 23 260 3.4E-51 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS17870 641d3b50bef3c25645f297b91b5dc7e4 262 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 125 142 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CU254_RS17870 641d3b50bef3c25645f297b91b5dc7e4 262 Gene3D G3DSA:3.20.20.100 3 262 9.0E-97 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS17870 641d3b50bef3c25645f297b91b5dc7e4 262 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 41 58 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CU254_RS33035 2d3de16173f67bc5504965a0f7427374 424 Pfam PF04143 Sulphur transport 74 404 5.7E-63 T 28-03-2018 IPR007272 Sulphur transport domain CU254_RS01360 8a56259d320c9144513de8c7220e702a 287 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 60 211 9.8E-44 T 28-03-2018 CU254_RS01360 8a56259d320c9144513de8c7220e702a 287 Gene3D G3DSA:3.40.30.10 121 222 1.2E-13 T 28-03-2018 CU254_RS01360 8a56259d320c9144513de8c7220e702a 287 SUPERFAMILY SSF52833 51 219 2.35E-42 T 28-03-2018 IPR012336 Thioredoxin-like fold CU254_RS13935 99e7e0f3dd75231bd947d7c5b329d032 288 Pfam PF00494 Squalene/phytoene synthase 20 269 4.3E-58 T 28-03-2018 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 CU254_RS13935 99e7e0f3dd75231bd947d7c5b329d032 288 Gene3D G3DSA:1.10.600.10 4 283 8.4E-65 T 28-03-2018 IPR008949 Isoprenoid synthase domain CU254_RS13935 99e7e0f3dd75231bd947d7c5b329d032 288 TIGRFAM TIGR03464 HpnC: squalene synthase HpnC 19 273 1.3E-80 T 28-03-2018 IPR017827 Squalene synthase HpnC CU254_RS13935 99e7e0f3dd75231bd947d7c5b329d032 288 SUPERFAMILY SSF48576 19 281 3.88E-55 T 28-03-2018 IPR008949 Isoprenoid synthase domain CU254_RS17665 4e00e3146bfcb077e4575a4d1d40bf20 324 Gene3D G3DSA:3.20.20.140 1 324 4.0E-67 T 28-03-2018 CU254_RS17665 4e00e3146bfcb077e4575a4d1d40bf20 324 Pfam PF04909 Amidohydrolase 4 324 2.5E-45 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CU254_RS17665 4e00e3146bfcb077e4575a4d1d40bf20 324 SUPERFAMILY SSF51556 3 324 1.36E-80 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS29115 302429bbd42200c18437380244007457 415 Pfam PF07690 Major Facilitator Superfamily 30 279 8.3E-19 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS29115 302429bbd42200c18437380244007457 415 Gene3D G3DSA:1.20.1250.20 22 211 4.5E-22 T 28-03-2018 CU254_RS29115 302429bbd42200c18437380244007457 415 PRINTS PR01035 Tetracycline resistance protein signature 153 175 9.7E-8 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CU254_RS29115 302429bbd42200c18437380244007457 415 PRINTS PR01035 Tetracycline resistance protein signature 36 52 9.7E-8 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CU254_RS29115 302429bbd42200c18437380244007457 415 PRINTS PR01035 Tetracycline resistance protein signature 293 314 9.7E-8 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CU254_RS29115 302429bbd42200c18437380244007457 415 Gene3D G3DSA:1.20.1250.20 216 406 3.7E-13 T 28-03-2018 CU254_RS29115 302429bbd42200c18437380244007457 415 SUPERFAMILY SSF103473 25 404 1.83E-43 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS24365 58d5464b2774d26c6938052d92c469c6 434 Pfam PF03055 Retinal pigment epithelial membrane protein 12 431 3.2E-102 T 28-03-2018 IPR004294 Carotenoid oxygenase GO:0016702|GO:0055114 CU254_RS17855 8844a28a3a037c5ea3fcc1cc2fa61f0c 281 SUPERFAMILY SSF55021 3 81 1.83E-13 T 28-03-2018 CU254_RS17855 8844a28a3a037c5ea3fcc1cc2fa61f0c 281 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 86 108 9.7E-51 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CU254_RS17855 8844a28a3a037c5ea3fcc1cc2fa61f0c 281 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 254 279 9.7E-51 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CU254_RS17855 8844a28a3a037c5ea3fcc1cc2fa61f0c 281 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 38 50 9.7E-51 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CU254_RS17855 8844a28a3a037c5ea3fcc1cc2fa61f0c 281 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 108 135 9.7E-51 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CU254_RS17855 8844a28a3a037c5ea3fcc1cc2fa61f0c 281 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 6 32 9.7E-51 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CU254_RS17855 8844a28a3a037c5ea3fcc1cc2fa61f0c 281 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 232 254 9.7E-51 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CU254_RS17855 8844a28a3a037c5ea3fcc1cc2fa61f0c 281 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 1 280 44.246 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CU254_RS17855 8844a28a3a037c5ea3fcc1cc2fa61f0c 281 PIRSF PIRSF036480 1 281 4.4E-105 T 28-03-2018 CU254_RS17855 8844a28a3a037c5ea3fcc1cc2fa61f0c 281 Gene3D G3DSA:3.30.70.260 1 88 3.2E-19 T 28-03-2018 CU254_RS17855 8844a28a3a037c5ea3fcc1cc2fa61f0c 281 Gene3D G3DSA:3.40.50.170 89 281 2.8E-56 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CU254_RS17855 8844a28a3a037c5ea3fcc1cc2fa61f0c 281 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 5 280 1.9E-95 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CU254_RS17855 8844a28a3a037c5ea3fcc1cc2fa61f0c 281 SUPERFAMILY SSF53328 86 281 4.84E-62 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CU254_RS17855 8844a28a3a037c5ea3fcc1cc2fa61f0c 281 Pfam PF00551 Formyl transferase 86 262 6.4E-38 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CU254_RS00570 47f57d8a2f1fedac520d622ba9d3f7a0 351 SUPERFAMILY SSF111331 82 142 1.23E-9 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain CU254_RS00570 47f57d8a2f1fedac520d622ba9d3f7a0 351 Pfam PF01513 ATP-NAD kinase 7 277 1.5E-15 T 28-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CU254_RS00570 47f57d8a2f1fedac520d622ba9d3f7a0 351 PIRSF PIRSF018567 2 340 4.1E-100 T 28-03-2018 IPR011391 Acetoin catabolism kinase AcoX CU254_RS00570 47f57d8a2f1fedac520d622ba9d3f7a0 351 Gene3D G3DSA:3.40.50.10330 4 195 1.4E-16 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 CU254_RS08700 b8f6b67bfa05c98f52162211f4526cca 289 SUPERFAMILY SSF52151 8 204 1.62E-47 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CU254_RS08700 b8f6b67bfa05c98f52162211f4526cca 289 Pfam PF01734 Patatin-like phospholipase 13 182 6.7E-23 T 28-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 CU254_RS08700 b8f6b67bfa05c98f52162211f4526cca 289 Gene3D G3DSA:3.40.1090.10 2 203 7.2E-43 T 28-03-2018 CU254_RS41600 a4507cf5b78f10a6cf92b621439251c4 145 SUPERFAMILY SSF47413 37 84 2.96E-6 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS41600 a4507cf5b78f10a6cf92b621439251c4 145 Pfam PF01381 Helix-turn-helix 38 84 5.1E-6 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS41600 a4507cf5b78f10a6cf92b621439251c4 145 Gene3D G3DSA:1.10.260.40 13 104 1.7E-8 T 28-03-2018 CU254_RS39060 c73c8e40cce063b55427c248425cbe72 291 Gene3D G3DSA:3.40.50.300 1 279 1.1E-58 T 28-03-2018 CU254_RS39060 c73c8e40cce063b55427c248425cbe72 291 SMART SM00382 26 204 5.5E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS39060 c73c8e40cce063b55427c248425cbe72 291 SUPERFAMILY SSF52540 2 216 2.66E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS39060 c73c8e40cce063b55427c248425cbe72 291 ProSitePatterns PS00211 ABC transporters family signature. 128 142 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS39060 c73c8e40cce063b55427c248425cbe72 291 Pfam PF00005 ABC transporter 18 156 2.3E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS11690 401aef01f78e96d2086c8925e6c118c0 76 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 3 73 7.2E-20 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CU254_RS11690 401aef01f78e96d2086c8925e6c118c0 76 Pfam PF03840 Preprotein translocase SecG subunit 4 72 4.4E-18 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CU254_RS11690 401aef01f78e96d2086c8925e6c118c0 76 PRINTS PR01651 Protein-export SecG membrane protein signature 3 23 2.8E-5 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CU254_RS11690 401aef01f78e96d2086c8925e6c118c0 76 PRINTS PR01651 Protein-export SecG membrane protein signature 23 37 2.8E-5 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CU254_RS11690 401aef01f78e96d2086c8925e6c118c0 76 PRINTS PR01651 Protein-export SecG membrane protein signature 54 76 2.8E-5 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CU254_RS16810 f3c2bbd189e45d5244981e0a442ce8ff 155 SUPERFAMILY SSF54909 15 119 9.01E-13 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS16810 f3c2bbd189e45d5244981e0a442ce8ff 155 Pfam PF11695 Domain of unknown function (DUF3291) 6 144 1.9E-53 T 28-03-2018 IPR021708 Domain of unknown function DUF3291 CU254_RS16810 f3c2bbd189e45d5244981e0a442ce8ff 155 Gene3D G3DSA:3.30.70.100 8 108 0.0043 T 28-03-2018 CU254_RS37305 c1524d87cdb6bae0ec234a3d0a57077d 146 SUPERFAMILY SSF53927 3 142 2.13E-42 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CU254_RS37305 c1524d87cdb6bae0ec234a3d0a57077d 146 Pfam PF14437 MafB19-like deaminase 9 140 3.4E-23 T 28-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 CU254_RS37305 c1524d87cdb6bae0ec234a3d0a57077d 146 Gene3D G3DSA:3.40.140.10 1 146 1.5E-39 T 28-03-2018 CU254_RS37305 c1524d87cdb6bae0ec234a3d0a57077d 146 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 45 83 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CU254_RS37305 c1524d87cdb6bae0ec234a3d0a57077d 146 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 1 142 44.044 T 28-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 CU254_RS04405 ee84731502f2eb9aba122ec6dff3944e 324 SMART SM00710 97 118 2600.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CU254_RS04405 ee84731502f2eb9aba122ec6dff3944e 324 SMART SM00710 119 141 1400.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CU254_RS04405 ee84731502f2eb9aba122ec6dff3944e 324 SMART SM00710 271 295 3700.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CU254_RS04405 ee84731502f2eb9aba122ec6dff3944e 324 SMART SM00710 209 245 1500.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CU254_RS04405 ee84731502f2eb9aba122ec6dff3944e 324 SMART SM00710 143 171 85.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CU254_RS04405 ee84731502f2eb9aba122ec6dff3944e 324 SUPERFAMILY SSF51126 16 314 6.6E-31 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor CU254_RS04405 ee84731502f2eb9aba122ec6dff3944e 324 Pfam PF13229 Right handed beta helix region 93 238 9.8E-6 T 28-03-2018 CU254_RS04405 ee84731502f2eb9aba122ec6dff3944e 324 Gene3D G3DSA:2.160.20.10 30 322 5.7E-26 T 28-03-2018 IPR012334 Pectin lyase fold CU254_RS18810 880881fb7110471263ca745276dfcb4a 267 Gene3D G3DSA:3.60.110.10 1 267 4.0E-65 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CU254_RS18810 880881fb7110471263ca745276dfcb4a 267 SUPERFAMILY SSF56317 3 266 1.44E-60 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CU254_RS18810 880881fb7110471263ca745276dfcb4a 267 Pfam PF00795 Carbon-nitrogen hydrolase 6 234 8.4E-35 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CU254_RS18810 880881fb7110471263ca745276dfcb4a 267 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 141 161 - T 28-03-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site CU254_RS31510 7851a1bf29f8294a84089917e21c94ed 476 Gene3D G3DSA:3.30.465.10 126 263 1.7E-35 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CU254_RS31510 7851a1bf29f8294a84089917e21c94ed 476 SUPERFAMILY SSF56176 38 237 6.07E-45 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CU254_RS31510 7851a1bf29f8294a84089917e21c94ed 476 Pfam PF01565 FAD binding domain 71 198 7.6E-29 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CU254_RS31510 7851a1bf29f8294a84089917e21c94ed 476 Gene3D G3DSA:3.30.43.10 18 124 2.4E-14 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CU254_RS31510 7851a1bf29f8294a84089917e21c94ed 476 Pfam PF08031 Berberine and berberine like 428 470 8.4E-11 T 28-03-2018 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 CU254_RS15245 7f6d61b0042b5991395436f2642f77c7 229 Gene3D G3DSA:3.40.50.300 6 228 2.0E-59 T 28-03-2018 CU254_RS15245 7f6d61b0042b5991395436f2642f77c7 229 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS15245 7f6d61b0042b5991395436f2642f77c7 229 SUPERFAMILY SSF52540 10 225 2.08E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS15245 7f6d61b0042b5991395436f2642f77c7 229 Pfam PF00005 ABC transporter 24 172 9.8E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS15245 7f6d61b0042b5991395436f2642f77c7 229 SMART SM00382 33 221 1.1E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS36375 0447f895e3f35917c122bbf01e8895dd 172 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 1 158 32.61 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 CU254_RS36375 0447f895e3f35917c122bbf01e8895dd 172 Pfam PF00719 Inorganic pyrophosphatase 5 156 4.2E-54 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 CU254_RS36375 0447f895e3f35917c122bbf01e8895dd 172 SUPERFAMILY SSF50324 3 168 2.49E-57 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 CU254_RS36375 0447f895e3f35917c122bbf01e8895dd 172 Gene3D G3DSA:3.90.80.10 1 165 8.0E-54 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 CU254_RS36375 0447f895e3f35917c122bbf01e8895dd 172 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 52 58 - T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 CU254_RS28610 50805985fd608b37c6ba7af4631d1522 203 Gene3D G3DSA:1.10.287.1060 10 95 8.1E-6 T 28-03-2018 CU254_RS22905 89a1181ee3936a00dbef9bd3bcbf3bb7 391 Pfam PF13458 Periplasmic binding protein 54 383 1.9E-41 T 28-03-2018 IPR028081 Leucine-binding protein domain CU254_RS22905 89a1181ee3936a00dbef9bd3bcbf3bb7 391 SUPERFAMILY SSF53822 55 385 1.85E-67 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CU254_RS22905 89a1181ee3936a00dbef9bd3bcbf3bb7 391 Gene3D G3DSA:3.40.50.2300 51 231 1.3E-30 T 28-03-2018 CU254_RS22905 89a1181ee3936a00dbef9bd3bcbf3bb7 391 Gene3D G3DSA:3.40.50.2300 232 371 1.7E-16 T 28-03-2018 CU254_RS03780 ecce6dae52473c492692eb1cf8833623 142 TIGRFAM TIGR01410 tatB: twin arginine-targeting protein translocase TatB 5 83 3.3E-17 T 28-03-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 CU254_RS03780 ecce6dae52473c492692eb1cf8833623 142 Hamap MF_00237 Sec-independent protein translocase protein TatB [tatB]. 2 136 13.803 T 28-03-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 CU254_RS03780 ecce6dae52473c492692eb1cf8833623 142 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 41 59 2.5E-10 T 28-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 CU254_RS03780 ecce6dae52473c492692eb1cf8833623 142 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 2 22 2.5E-10 T 28-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 CU254_RS03780 ecce6dae52473c492692eb1cf8833623 142 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 22 41 2.5E-10 T 28-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 CU254_RS29285 d7037c0ae340e3631423aa49f218deae 333 SUPERFAMILY SSF51556 2 333 4.62E-71 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS29285 d7037c0ae340e3631423aa49f218deae 333 Gene3D G3DSA:3.20.20.140 1 333 8.5E-50 T 28-03-2018 CU254_RS29285 d7037c0ae340e3631423aa49f218deae 333 Pfam PF04909 Amidohydrolase 3 333 8.1E-54 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CU254_RS20395 6c56018ce58cacecfbb3bd549ad0a0da 405 SUPERFAMILY SSF51338 6 51 1.18E-16 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS20395 6c56018ce58cacecfbb3bd549ad0a0da 405 SUPERFAMILY SSF51338 361 403 1.18E-16 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS20395 6c56018ce58cacecfbb3bd549ad0a0da 405 SUPERFAMILY SSF51556 51 361 1.76E-80 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS20395 6c56018ce58cacecfbb3bd549ad0a0da 405 Gene3D G3DSA:3.20.20.140 66 342 1.5E-44 T 28-03-2018 CU254_RS20395 6c56018ce58cacecfbb3bd549ad0a0da 405 Gene3D G3DSA:2.30.40.10 4 65 1.6E-12 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS20395 6c56018ce58cacecfbb3bd549ad0a0da 405 Gene3D G3DSA:3.20.20.140 343 377 6.2E-4 T 28-03-2018 CU254_RS20395 6c56018ce58cacecfbb3bd549ad0a0da 405 Pfam PF01979 Amidohydrolase family 47 401 1.5E-39 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CU254_RS15075 661dd92a199bea32577a1d65f893e85c 687 Pfam PF04185 Phosphoesterase family 44 432 1.6E-114 T 28-03-2018 IPR007312 Phosphoesterase GO:0016788 CU254_RS15075 661dd92a199bea32577a1d65f893e85c 687 SUPERFAMILY SSF53649 381 424 1.52E-6 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CU254_RS15075 661dd92a199bea32577a1d65f893e85c 687 SUPERFAMILY SSF53649 149 351 1.52E-6 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CU254_RS15075 661dd92a199bea32577a1d65f893e85c 687 Pfam PF05506 Domain of unknown function (DUF756) 502 586 2.1E-18 T 28-03-2018 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 CU254_RS15075 661dd92a199bea32577a1d65f893e85c 687 Pfam PF05506 Domain of unknown function (DUF756) 600 671 4.1E-9 T 28-03-2018 IPR008475 Bacterial phospholipase C, C-terminal domain GO:0004629|GO:0016042 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 CU254_RS15075 661dd92a199bea32577a1d65f893e85c 687 Gene3D G3DSA:3.40.720.10 103 437 1.2E-22 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CU254_RS15075 661dd92a199bea32577a1d65f893e85c 687 TIGRFAM TIGR03396 PC_PLC: phospholipase C, phosphocholine-specific 5 685 6.1E-249 T 28-03-2018 IPR017767 Bacterial phospholipase C, phosphocholine-specific GO:0034480 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 CU254_RS05425 579be8fdfcfd40540facc8b8b1d0d209 354 Gene3D G3DSA:3.30.565.10 185 354 1.1E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS05425 579be8fdfcfd40540facc8b8b1d0d209 354 Pfam PF07730 Histidine kinase 178 244 3.2E-18 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CU254_RS05425 579be8fdfcfd40540facc8b8b1d0d209 354 SUPERFAMILY SSF55874 274 353 6.21E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS06090 71f94383cadf8640e5119d6362b672ec 521 Pfam PF13449 Esterase-like activity of phytase 115 470 9.1E-60 T 28-03-2018 IPR027372 Phytase-like domain CU254_RS06090 71f94383cadf8640e5119d6362b672ec 521 SUPERFAMILY SSF63829 212 347 7.85E-5 T 28-03-2018 CU254_RS06090 71f94383cadf8640e5119d6362b672ec 521 Gene3D G3DSA:2.60.120.640 34 121 7.7E-13 T 28-03-2018 CU254_RS06090 71f94383cadf8640e5119d6362b672ec 521 Gene3D G3DSA:2.120.10.30 177 473 4.5E-4 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CU254_RS37390 f4a26aaefe6f1582cec48769c48cf6e1 139 Pfam PF00011 Hsp20/alpha crystallin family 34 130 1.4E-21 T 28-03-2018 IPR002068 Alpha crystallin/Hsp20 domain CU254_RS37390 f4a26aaefe6f1582cec48769c48cf6e1 139 Gene3D G3DSA:2.60.40.790 4 131 4.6E-28 T 28-03-2018 IPR008978 HSP20-like chaperone CU254_RS37390 f4a26aaefe6f1582cec48769c48cf6e1 139 SUPERFAMILY SSF49764 10 130 2.76E-29 T 28-03-2018 IPR008978 HSP20-like chaperone CU254_RS04845 9886ec9d5d99cda23571fc5de0a96bf2 229 Gene3D G3DSA:3.40.50.300 1 223 4.2E-64 T 28-03-2018 CU254_RS04845 9886ec9d5d99cda23571fc5de0a96bf2 229 Pfam PF00005 ABC transporter 19 166 5.9E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS04845 9886ec9d5d99cda23571fc5de0a96bf2 229 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS04845 9886ec9d5d99cda23571fc5de0a96bf2 229 SUPERFAMILY SSF52540 1 220 3.13E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS04845 9886ec9d5d99cda23571fc5de0a96bf2 229 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 214 3.3E-85 T 28-03-2018 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 CU254_RS04845 9886ec9d5d99cda23571fc5de0a96bf2 229 SMART SM00382 28 215 1.5E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS24825 08b6f69cb5bfd560abdb834da2ddb936 172 Pfam PF05534 HicB family 104 134 1.0E-5 T 28-03-2018 IPR008651 Uncharacterised protein family HicB CU254_RS24825 08b6f69cb5bfd560abdb834da2ddb936 172 SUPERFAMILY SSF47598 99 145 6.67E-9 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 CU254_RS24825 08b6f69cb5bfd560abdb834da2ddb936 172 Gene3D G3DSA:1.10.1220.10 102 138 4.2E-10 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CU254_RS09695 58f3e2363c64f07d6c780468769ca646 238 Pfam PF14099 Polysaccharide lyase 78 222 8.2E-16 T 28-03-2018 IPR025975 Polysaccharide lyase MetaCyc: PWY-7644 CU254_RS09695 58f3e2363c64f07d6c780468769ca646 238 SUPERFAMILY SSF49899 115 197 1.37E-5 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CU254_RS09695 58f3e2363c64f07d6c780468769ca646 238 Gene3D G3DSA:2.60.120.200 21 236 7.3E-7 T 28-03-2018 CU254_RS00650 acb6de0133f2fac0b843c1cd2e940169 600 Pfam PF02927 Cellulase N-terminal ig-like domain 39 118 1.0E-16 T 28-03-2018 IPR004197 Cellulase, Ig-like domain GO:0005975|GO:0008810 CU254_RS00650 acb6de0133f2fac0b843c1cd2e940169 600 Pfam PF00759 Glycosyl hydrolase family 9 136 535 1.0E-22 T 28-03-2018 IPR001701 Glycoside hydrolase family 9 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 CU254_RS00650 acb6de0133f2fac0b843c1cd2e940169 600 Gene3D G3DSA:1.50.10.10 127 591 1.4E-55 T 28-03-2018 CU254_RS00650 acb6de0133f2fac0b843c1cd2e940169 600 SUPERFAMILY SSF81296 38 127 5.32E-18 T 28-03-2018 IPR014756 Immunoglobulin E-set CU254_RS00650 acb6de0133f2fac0b843c1cd2e940169 600 Gene3D G3DSA:2.60.40.10 38 126 1.2E-22 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS00650 acb6de0133f2fac0b843c1cd2e940169 600 SUPERFAMILY SSF48208 128 597 1.27E-51 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CU254_RS22595 c23ef8a8552cc8a5db2381fb2635cc8a 447 PRINTS PR00173 Glutamate-aspartate symporter signature 333 352 5.8E-30 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CU254_RS22595 c23ef8a8552cc8a5db2381fb2635cc8a 447 PRINTS PR00173 Glutamate-aspartate symporter signature 197 216 5.8E-30 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CU254_RS22595 c23ef8a8552cc8a5db2381fb2635cc8a 447 PRINTS PR00173 Glutamate-aspartate symporter signature 54 74 5.8E-30 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CU254_RS22595 c23ef8a8552cc8a5db2381fb2635cc8a 447 PRINTS PR00173 Glutamate-aspartate symporter signature 84 109 5.8E-30 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CU254_RS22595 c23ef8a8552cc8a5db2381fb2635cc8a 447 PRINTS PR00173 Glutamate-aspartate symporter signature 13 33 5.8E-30 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CU254_RS22595 c23ef8a8552cc8a5db2381fb2635cc8a 447 PRINTS PR00173 Glutamate-aspartate symporter signature 298 324 5.8E-30 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CU254_RS22595 c23ef8a8552cc8a5db2381fb2635cc8a 447 Gene3D G3DSA:1.10.3860.10 12 414 4.9E-106 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CU254_RS22595 c23ef8a8552cc8a5db2381fb2635cc8a 447 Pfam PF00375 Sodium:dicarboxylate symporter family 19 406 1.2E-98 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CU254_RS22595 c23ef8a8552cc8a5db2381fb2635cc8a 447 SUPERFAMILY SSF118215 19 407 1.44E-104 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CU254_RS17375 b37b6a4e0626dcd4217d1ce52f8425d6 424 PIRSF PIRSF005572 24 406 1.0E-48 T 28-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CU254_RS17375 b37b6a4e0626dcd4217d1ce52f8425d6 424 SUPERFAMILY SSF53383 10 403 1.06E-114 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS17375 b37b6a4e0626dcd4217d1ce52f8425d6 424 Pfam PF00266 Aminotransferase class-V 27 397 1.4E-122 T 28-03-2018 IPR000192 Aminotransferase class V domain CU254_RS17375 b37b6a4e0626dcd4217d1ce52f8425d6 424 Gene3D G3DSA:3.40.640.10 36 285 5.2E-57 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS17375 b37b6a4e0626dcd4217d1ce52f8425d6 424 Gene3D G3DSA:3.90.1150.10 286 405 3.1E-36 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS40425 a214f01cca907222522bbb0fd51f1e10 303 SUPERFAMILY SSF53448 17 269 1.8E-28 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS40425 a214f01cca907222522bbb0fd51f1e10 303 Pfam PF00535 Glycosyl transferase family 2 17 122 2.1E-12 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CU254_RS40425 a214f01cca907222522bbb0fd51f1e10 303 Gene3D G3DSA:3.90.550.10 7 256 1.1E-17 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS31755 e759065ebff373265d27239a1f5c2f29 594 Pfam PF12077 Transmembrane protein of unknown function (DUF3556) 1 581 1.2E-261 T 28-03-2018 IPR021941 Protein of unknown function DUF3556, transmembrane CU254_RS39640 d858f53593c6a8f5c8820df42bb70e9c 461 Pfam PF01425 Amidase 25 442 6.6E-83 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS39640 d858f53593c6a8f5c8820df42bb70e9c 461 SUPERFAMILY SSF75304 1 459 3.66E-119 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS39640 d858f53593c6a8f5c8820df42bb70e9c 461 Gene3D G3DSA:3.90.1300.10 1 461 5.6E-122 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS10085 988ea85a166a9df319b3c69a8fcf68ef 253 SMART SM00563 35 154 1.3E-32 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CU254_RS10085 988ea85a166a9df319b3c69a8fcf68ef 253 SUPERFAMILY SSF69593 2 226 2.88E-51 T 28-03-2018 CU254_RS10085 988ea85a166a9df319b3c69a8fcf68ef 253 Pfam PF01553 Acyltransferase 22 151 2.6E-21 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CU254_RS10085 988ea85a166a9df319b3c69a8fcf68ef 253 Gene3D G3DSA:3.40.1130.10 4 230 3.0E-53 T 28-03-2018 CU254_RS00240 fea3a20f0fd564ff4e4bc8f3ecbe164d 85 SUPERFAMILY SSF47336 6 79 9.42E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS00240 fea3a20f0fd564ff4e4bc8f3ecbe164d 85 Gene3D G3DSA:1.10.1200.10 6 85 5.4E-15 T 28-03-2018 CU254_RS00240 fea3a20f0fd564ff4e4bc8f3ecbe164d 85 Pfam PF00550 Phosphopantetheine attachment site 7 71 2.8E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS01465 c620116ad6d7a8c1548b50de2d6b9bbe 153 Gene3D G3DSA:1.10.3300.10 2 153 2.2E-27 T 28-03-2018 IPR023286 ABATE domain CU254_RS01465 c620116ad6d7a8c1548b50de2d6b9bbe 153 SUPERFAMILY SSF160904 3 151 8.5E-30 T 28-03-2018 CU254_RS01465 c620116ad6d7a8c1548b50de2d6b9bbe 153 Pfam PF11706 CGNR zinc finger 109 151 4.4E-18 T 28-03-2018 IPR021005 Zinc finger, CGNR CU254_RS08025 7b0670f83f7dfb1ba4191ad23534264b 390 Gene3D G3DSA:1.10.10.10 310 385 1.1E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS08025 7b0670f83f7dfb1ba4191ad23534264b 390 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 77 307 3.0E-61 T 28-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 CU254_RS08025 7b0670f83f7dfb1ba4191ad23534264b 390 Pfam PF02481 DNA recombination-mediator protein A 80 299 1.4E-63 T 28-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 CU254_RS08025 7b0670f83f7dfb1ba4191ad23534264b 390 Gene3D G3DSA:3.40.50.450 131 278 1.3E-30 T 28-03-2018 CU254_RS08025 7b0670f83f7dfb1ba4191ad23534264b 390 SUPERFAMILY SSF102405 116 307 2.29E-31 T 28-03-2018 CU254_RS12370 3fecc308080a3237c84fc3629098e996 498 Pfam PF04945 YHS domain 416 445 1.2E-8 T 28-03-2018 IPR007029 YHS domain CU254_RS12370 3fecc308080a3237c84fc3629098e996 498 Gene3D G3DSA:1.10.620.20 1 498 3.0E-138 T 28-03-2018 CU254_RS12370 3fecc308080a3237c84fc3629098e996 498 Pfam PF02332 Methane/Phenol/Toluene Hydroxylase 18 248 1.1E-72 T 28-03-2018 IPR003430 Methane/phenol/toluene hydroxylase GO:0006725|GO:0055114 CU254_RS12370 3fecc308080a3237c84fc3629098e996 498 SUPERFAMILY SSF47240 6 491 5.8E-150 T 28-03-2018 IPR009078 Ferritin-like superfamily CU254_RS24670 2300fc9a5c584199cb576d029c2b5b07 852 SUPERFAMILY SSF54001 443 572 1.54E-30 T 28-03-2018 CU254_RS24670 2300fc9a5c584199cb576d029c2b5b07 852 Pfam PF01841 Transglutaminase-like superfamily 447 562 2.7E-26 T 28-03-2018 IPR002931 Transglutaminase-like CU254_RS24670 2300fc9a5c584199cb576d029c2b5b07 852 SMART SM00460 495 564 1.1E-18 T 28-03-2018 IPR002931 Transglutaminase-like CU254_RS24670 2300fc9a5c584199cb576d029c2b5b07 852 Gene3D G3DSA:3.90.260.10 444 579 6.0E-18 T 28-03-2018 IPR002931 Transglutaminase-like CU254_RS40410 79ffa7ca3fde67521bb1f8f2a013ae18 255 Pfam PF14011 EspG family 8 244 3.7E-56 T 28-03-2018 IPR025734 EspG family CU254_RS03185 2e4665a0aa6b43eab6fc4fbf26122c86 249 Pfam PF00230 Major intrinsic protein 8 242 1.6E-39 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CU254_RS03185 2e4665a0aa6b43eab6fc4fbf26122c86 249 Gene3D G3DSA:1.20.1080.10 2 249 1.4E-73 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CU254_RS03185 2e4665a0aa6b43eab6fc4fbf26122c86 249 PRINTS PR00783 Major intrinsic protein family signature 177 199 1.5E-33 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CU254_RS03185 2e4665a0aa6b43eab6fc4fbf26122c86 249 PRINTS PR00783 Major intrinsic protein family signature 46 70 1.5E-33 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CU254_RS03185 2e4665a0aa6b43eab6fc4fbf26122c86 249 PRINTS PR00783 Major intrinsic protein family signature 5 24 1.5E-33 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CU254_RS03185 2e4665a0aa6b43eab6fc4fbf26122c86 249 PRINTS PR00783 Major intrinsic protein family signature 225 245 1.5E-33 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CU254_RS03185 2e4665a0aa6b43eab6fc4fbf26122c86 249 PRINTS PR00783 Major intrinsic protein family signature 138 156 1.5E-33 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CU254_RS03185 2e4665a0aa6b43eab6fc4fbf26122c86 249 PRINTS PR00783 Major intrinsic protein family signature 83 102 1.5E-33 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CU254_RS03185 2e4665a0aa6b43eab6fc4fbf26122c86 249 SUPERFAMILY SSF81338 7 245 2.88E-57 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CU254_RS03185 2e4665a0aa6b43eab6fc4fbf26122c86 249 ProSitePatterns PS00221 MIP family signature. 64 72 - T 28-03-2018 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CU254_RS35680 bbdf35112722c1afb4ffa8c7001bca82 284 Gene3D G3DSA:3.20.20.140 4 282 3.0E-43 T 28-03-2018 CU254_RS35680 bbdf35112722c1afb4ffa8c7001bca82 284 Pfam PF04909 Amidohydrolase 9 279 4.4E-38 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CU254_RS35680 bbdf35112722c1afb4ffa8c7001bca82 284 SUPERFAMILY SSF51556 6 281 6.31E-51 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS15285 1a0cfa84c62390314bb09269513ffc2a 290 Gene3D G3DSA:3.50.30.50 20 290 3.4E-52 T 28-03-2018 CU254_RS15285 1a0cfa84c62390314bb09269513ffc2a 290 Pfam PF04199 Putative cyclase 25 225 1.3E-26 T 28-03-2018 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 CU254_RS15285 1a0cfa84c62390314bb09269513ffc2a 290 SUPERFAMILY SSF102198 23 290 9.68E-40 T 28-03-2018 CU254_RS25280 34ddaeb9c2145f5283458fa2c06f8f5f 250 Pfam PF07090 Putative glutamine amidotransferase 3 245 8.9E-97 T 28-03-2018 IPR010768 Putative glutamine amidotransferase CU254_RS25280 34ddaeb9c2145f5283458fa2c06f8f5f 250 SUPERFAMILY SSF52317 3 247 1.98E-69 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS25280 34ddaeb9c2145f5283458fa2c06f8f5f 250 Gene3D G3DSA:3.40.50.880 1 248 4.4E-52 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS34450 3e5bf52fb7d604797af54f9fa833fb8c 390 Gene3D G3DSA:1.10.540.10 1 119 3.7E-22 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS34450 3e5bf52fb7d604797af54f9fa833fb8c 390 Gene3D G3DSA:2.40.110.10 120 218 7.2E-33 T 28-03-2018 CU254_RS34450 3e5bf52fb7d604797af54f9fa833fb8c 390 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 387 5.3E-16 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS34450 3e5bf52fb7d604797af54f9fa833fb8c 390 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 126 219 6.8E-20 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CU254_RS34450 3e5bf52fb7d604797af54f9fa833fb8c 390 Gene3D G3DSA:1.20.140.10 219 390 6.3E-34 T 28-03-2018 CU254_RS34450 3e5bf52fb7d604797af54f9fa833fb8c 390 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 118 1.3E-15 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CU254_RS34450 3e5bf52fb7d604797af54f9fa833fb8c 390 SUPERFAMILY SSF47203 231 390 4.19E-17 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CU254_RS34450 3e5bf52fb7d604797af54f9fa833fb8c 390 SUPERFAMILY SSF56645 2 244 1.96E-70 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CU254_RS31135 1bbca5391b827f7078a71df9ab9c3cb4 332 Gene3D G3DSA:3.40.190.10 4 313 5.1E-4 T 28-03-2018 CU254_RS09970 1a7203b7ebff399e32ebb205075213e7 157 SUPERFAMILY SSF54427 34 153 2.12E-5 T 28-03-2018 IPR032710 NTF2-like domain CU254_RS09970 1a7203b7ebff399e32ebb205075213e7 157 Gene3D G3DSA:3.10.450.50 33 155 4.5E-6 T 28-03-2018 CU254_RS19300 4a0f959f4a5c71436a000a8aa8c2e432 122 Pfam PF13490 Putative zinc-finger 3 37 1.4E-4 T 28-03-2018 IPR027383 Putative zinc-finger CU254_RS15880 9fe229410ab31c42fe5ab123e60b4661 456 SUPERFAMILY SSF53720 8 451 1.57E-118 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CU254_RS15880 9fe229410ab31c42fe5ab123e60b4661 456 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 262 273 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CU254_RS15880 9fe229410ab31c42fe5ab123e60b4661 456 Gene3D G3DSA:3.40.309.10 253 418 8.0E-48 T 28-03-2018 CU254_RS15880 9fe229410ab31c42fe5ab123e60b4661 456 Gene3D G3DSA:3.40.605.10 3 252 8.2E-70 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CU254_RS15880 9fe229410ab31c42fe5ab123e60b4661 456 Pfam PF00171 Aldehyde dehydrogenase family 8 448 6.0E-111 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CU254_RS23355 4a29893375a69da80225524f27101485 159 Gene3D G3DSA:1.20.120.520 8 146 9.8E-23 T 28-03-2018 CU254_RS23355 4a29893375a69da80225524f27101485 159 Pfam PF01814 Hemerythrin HHE cation binding domain 6 123 5.9E-14 T 28-03-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 CU254_RS10875 971fc2c8343fe127349a7da34e4108cf 164 Pfam PF11292 Protein of unknown function (DUF3093) 15 157 3.1E-46 T 28-03-2018 IPR021443 Protein of unknown function DUF3093 CU254_RS21320 61e1e3a9af31a8a116231ea4c9a9b72c 259 Pfam PF13229 Right handed beta helix region 54 232 4.3E-10 T 28-03-2018 CU254_RS21320 61e1e3a9af31a8a116231ea4c9a9b72c 259 SUPERFAMILY SSF51126 16 235 2.69E-19 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor CU254_RS21320 61e1e3a9af31a8a116231ea4c9a9b72c 259 Gene3D G3DSA:2.160.20.10 5 250 1.6E-17 T 28-03-2018 IPR012334 Pectin lyase fold CU254_RS30000 ebac382053934ab258273c7f34623173 302 Hamap MF_01818 Ribonuclease BN [rbn]. 4 298 28.274 T 28-03-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 CU254_RS30000 ebac382053934ab258273c7f34623173 302 SUPERFAMILY SSF56281 5 298 2.75E-57 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS30000 ebac382053934ab258273c7f34623173 302 Gene3D G3DSA:3.60.15.10 4 302 7.4E-50 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS30000 ebac382053934ab258273c7f34623173 302 Pfam PF00753 Metallo-beta-lactamase superfamily 20 108 5.0E-12 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS11525 1905fcc8d3fcd51c37d6801048d51589 700 SUPERFAMILY SSF52540 215 296 2.21E-6 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS11525 1905fcc8d3fcd51c37d6801048d51589 700 Hamap MF_00983 Probable primosomal protein N' [priA]. 56 699 20.179 T 28-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 CU254_RS11525 1905fcc8d3fcd51c37d6801048d51589 700 Gene3D G3DSA:3.40.50.300 191 420 4.9E-4 T 28-03-2018 CU254_RS31770 87083b55e26084237cf9ddef5dd7461c 94 Gene3D G3DSA:3.30.70.260 34 94 6.0E-4 T 28-03-2018 CU254_RS36615 28e0a64f591b04bc325091f9b861e434 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 247 2.4E-44 T 28-03-2018 CU254_RS36615 28e0a64f591b04bc325091f9b861e434 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 1.4E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS36615 28e0a64f591b04bc325091f9b861e434 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 1.4E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS36615 28e0a64f591b04bc325091f9b861e434 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 163 1.4E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS36615 28e0a64f591b04bc325091f9b861e434 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 182 1.4E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS36615 28e0a64f591b04bc325091f9b861e434 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 118 134 1.4E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS36615 28e0a64f591b04bc325091f9b861e434 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 71 82 1.4E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS36615 28e0a64f591b04bc325091f9b861e434 249 SUPERFAMILY SSF51735 9 248 2.31E-67 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS36615 28e0a64f591b04bc325091f9b861e434 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 71 82 4.6E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS36615 28e0a64f591b04bc325091f9b861e434 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 163 4.6E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS36615 28e0a64f591b04bc325091f9b861e434 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 124 132 4.6E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS36615 28e0a64f591b04bc325091f9b861e434 249 Gene3D G3DSA:3.40.50.720 9 249 3.0E-64 T 28-03-2018 CU254_RS36615 28e0a64f591b04bc325091f9b861e434 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 131 159 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS01765 28dea79980b3237d23015df0dcdc3fbc 250 Pfam PF02405 Permease MlaE 29 240 1.6E-65 T 28-03-2018 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 CU254_RS05905 cb211cbe0c94161bf7c4a0f41766e68b 270 Pfam PF03704 Bacterial transcriptional activator domain 96 241 5.3E-41 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CU254_RS05905 cb211cbe0c94161bf7c4a0f41766e68b 270 SMART SM00862 12 89 2.2E-8 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS05905 cb211cbe0c94161bf7c4a0f41766e68b 270 Gene3D G3DSA:1.25.40.10 93 260 2.1E-20 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS05905 cb211cbe0c94161bf7c4a0f41766e68b 270 SUPERFAMILY SSF46894 7 89 1.39E-14 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS05905 cb211cbe0c94161bf7c4a0f41766e68b 270 Gene3D G3DSA:1.10.10.10 1 92 2.9E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS05905 cb211cbe0c94161bf7c4a0f41766e68b 270 SMART SM01043 96 241 4.8E-41 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CU254_RS05905 cb211cbe0c94161bf7c4a0f41766e68b 270 SUPERFAMILY SSF48452 95 256 8.22E-34 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS05905 cb211cbe0c94161bf7c4a0f41766e68b 270 Pfam PF00486 Transcriptional regulatory protein, C terminal 19 89 2.7E-11 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS16000 7501d9b8a43fec10e421cea53c16532f 398 Gene3D G3DSA:3.40.710.10 1 300 1.9E-56 T 28-03-2018 CU254_RS16000 7501d9b8a43fec10e421cea53c16532f 398 SUPERFAMILY SSF56601 4 292 1.88E-54 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CU254_RS16000 7501d9b8a43fec10e421cea53c16532f 398 Pfam PF00144 Beta-lactamase 5 287 1.5E-46 T 28-03-2018 IPR001466 Beta-lactamase-related CU254_RS28410 f9bcdc72f89a969f32e86302a98ecd90 434 Gene3D G3DSA:1.20.1250.20 4 211 1.4E-21 T 28-03-2018 CU254_RS28410 f9bcdc72f89a969f32e86302a98ecd90 434 Gene3D G3DSA:1.20.1250.20 226 430 1.4E-16 T 28-03-2018 CU254_RS28410 f9bcdc72f89a969f32e86302a98ecd90 434 SUPERFAMILY SSF103473 9 421 2.49E-51 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS28410 f9bcdc72f89a969f32e86302a98ecd90 434 Pfam PF00083 Sugar (and other) transporter 12 222 3.2E-15 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CU254_RS29965 02d220370f5cfcf57999f1f206899a08 372 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 1.4E-18 T 28-03-2018 CU254_RS29965 02d220370f5cfcf57999f1f206899a08 372 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 145 160 1.4E-18 T 28-03-2018 CU254_RS29965 02d220370f5cfcf57999f1f206899a08 372 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 285 300 1.4E-18 T 28-03-2018 CU254_RS29965 02d220370f5cfcf57999f1f206899a08 372 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 300 316 1.4E-18 T 28-03-2018 CU254_RS29965 02d220370f5cfcf57999f1f206899a08 372 Pfam PF01494 FAD binding domain 3 45 9.8E-6 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CU254_RS29965 02d220370f5cfcf57999f1f206899a08 372 Pfam PF01494 FAD binding domain 143 335 9.5E-12 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CU254_RS29965 02d220370f5cfcf57999f1f206899a08 372 SUPERFAMILY SSF51905 270 363 6.72E-46 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS29965 02d220370f5cfcf57999f1f206899a08 372 SUPERFAMILY SSF51905 3 166 6.72E-46 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS29965 02d220370f5cfcf57999f1f206899a08 372 Gene3D G3DSA:3.50.50.60 2 368 4.0E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS12710 1ba4dc1ae4df209ca9c3aabe8f01d5a4 662 Pfam PF05547 Immune inhibitor A peptidase M6 478 651 5.4E-26 T 28-03-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 CU254_RS12710 1ba4dc1ae4df209ca9c3aabe8f01d5a4 662 Pfam PF05547 Immune inhibitor A peptidase M6 163 465 1.1E-59 T 28-03-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 CU254_RS12710 1ba4dc1ae4df209ca9c3aabe8f01d5a4 662 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 208 501 1.2E-59 T 28-03-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 CU254_RS12710 1ba4dc1ae4df209ca9c3aabe8f01d5a4 662 SUPERFAMILY SSF55486 328 442 9.36E-13 T 28-03-2018 CU254_RS12710 1ba4dc1ae4df209ca9c3aabe8f01d5a4 662 Gene3D G3DSA:3.40.390.10 193 455 6.4E-5 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CU254_RS06730 60951692a227d72b1ff6cc8978043102 294 Gene3D G3DSA:3.40.1130.10 53 272 6.1E-20 T 28-03-2018 CU254_RS06730 60951692a227d72b1ff6cc8978043102 294 SUPERFAMILY SSF69593 44 205 4.71E-18 T 28-03-2018 CU254_RS06730 60951692a227d72b1ff6cc8978043102 294 Pfam PF01553 Acyltransferase 88 202 3.1E-18 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CU254_RS06730 60951692a227d72b1ff6cc8978043102 294 SMART SM00563 93 205 4.7E-22 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CU254_RS06365 e1a8d97ee660b2b508c4abce34cbd101 246 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 73 212 2.1E-23 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CU254_RS06365 e1a8d97ee660b2b508c4abce34cbd101 246 SUPERFAMILY SSF50891 71 218 4.24E-30 T 28-03-2018 IPR029000 Cyclophilin-like domain CU254_RS06365 e1a8d97ee660b2b508c4abce34cbd101 246 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 175 187 1.7E-8 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CU254_RS06365 e1a8d97ee660b2b508c4abce34cbd101 246 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 80 95 1.7E-8 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CU254_RS06365 e1a8d97ee660b2b508c4abce34cbd101 246 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 160 175 1.7E-8 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CU254_RS06365 e1a8d97ee660b2b508c4abce34cbd101 246 Gene3D G3DSA:2.40.100.10 51 234 2.0E-35 T 28-03-2018 IPR029000 Cyclophilin-like domain CU254_RS07895 60800f52930aaf95281d821c6127bdaa 428 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 8 422 5.0E-179 T 28-03-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 CU254_RS07895 60800f52930aaf95281d821c6127bdaa 428 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 10 422 1.1E-130 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CU254_RS07895 60800f52930aaf95281d821c6127bdaa 428 Gene3D G3DSA:3.90.1150.10 291 428 1.0E-49 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS07895 60800f52930aaf95281d821c6127bdaa 428 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 200 214 - T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CU254_RS07895 60800f52930aaf95281d821c6127bdaa 428 Gene3D G3DSA:3.40.640.10 6 289 2.0E-61 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS07895 60800f52930aaf95281d821c6127bdaa 428 SUPERFAMILY SSF53383 6 423 5.85E-122 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS07895 60800f52930aaf95281d821c6127bdaa 428 PIRSF PIRSF001434 1 426 2.1E-126 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CU254_RS41025 cd8ee32500bbfea25fa6aa45ea3a2fa5 248 Pfam PF13419 Haloacid dehalogenase-like hydrolase 114 217 3.2E-10 T 28-03-2018 IPR023214 HAD-like domain CU254_RS41025 cd8ee32500bbfea25fa6aa45ea3a2fa5 248 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 156 213 3.9E-7 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CU254_RS41025 cd8ee32500bbfea25fa6aa45ea3a2fa5 248 Gene3D G3DSA:3.40.50.1000 101 243 1.1E-22 T 28-03-2018 IPR023214 HAD-like domain CU254_RS41025 cd8ee32500bbfea25fa6aa45ea3a2fa5 248 SUPERFAMILY SSF56784 14 241 1.84E-29 T 28-03-2018 IPR023214 HAD-like domain CU254_RS08355 d8fe841e41c58bfcde04109ad753e8bd 311 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 259 301 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CU254_RS08355 d8fe841e41c58bfcde04109ad753e8bd 311 SUPERFAMILY SSF52317 1 191 7.55E-44 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS08355 d8fe841e41c58bfcde04109ad753e8bd 311 Gene3D G3DSA:3.40.50.880 1 223 2.6E-55 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS08355 d8fe841e41c58bfcde04109ad753e8bd 311 Pfam PF01965 DJ-1/PfpI family 38 170 2.3E-15 T 28-03-2018 IPR002818 DJ-1/PfpI CU254_RS08355 d8fe841e41c58bfcde04109ad753e8bd 311 SMART SM00342 222 305 2.2E-29 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS08355 d8fe841e41c58bfcde04109ad753e8bd 311 Gene3D G3DSA:1.10.10.60 224 262 2.8E-10 T 28-03-2018 CU254_RS08355 d8fe841e41c58bfcde04109ad753e8bd 311 SUPERFAMILY SSF46689 210 255 4.39E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS08355 d8fe841e41c58bfcde04109ad753e8bd 311 Gene3D G3DSA:1.10.10.60 263 311 6.0E-16 T 28-03-2018 CU254_RS08355 d8fe841e41c58bfcde04109ad753e8bd 311 Pfam PF12833 Helix-turn-helix domain 228 306 7.8E-23 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS08355 d8fe841e41c58bfcde04109ad753e8bd 311 SUPERFAMILY SSF46689 258 309 7.53E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS42330 75df828ca0aebed2a45400a28bda4ef5 148 SUPERFAMILY SSF47413 77 132 2.82E-10 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS42330 75df828ca0aebed2a45400a28bda4ef5 148 Pfam PF01381 Helix-turn-helix 80 130 8.3E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS42330 75df828ca0aebed2a45400a28bda4ef5 148 Pfam PF01381 Helix-turn-helix 14 67 2.0E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS42330 75df828ca0aebed2a45400a28bda4ef5 148 Gene3D G3DSA:1.10.260.40 10 78 3.4E-16 T 28-03-2018 CU254_RS42330 75df828ca0aebed2a45400a28bda4ef5 148 SMART SM00530 77 132 1.4E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS42330 75df828ca0aebed2a45400a28bda4ef5 148 SMART SM00530 13 68 1.5E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS42330 75df828ca0aebed2a45400a28bda4ef5 148 SUPERFAMILY SSF47413 12 74 2.2E-13 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS42330 75df828ca0aebed2a45400a28bda4ef5 148 Gene3D G3DSA:1.10.260.40 79 124 8.4E-12 T 28-03-2018 CU254_RS42330 75df828ca0aebed2a45400a28bda4ef5 148 Gene3D G3DSA:1.10.10.10 125 147 0.054 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS22855 05047d19a3d20af9b1deef9c36d47659 335 SUPERFAMILY SSF55729 92 324 4.63E-23 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS22855 05047d19a3d20af9b1deef9c36d47659 335 Pfam PF00583 Acetyltransferase (GNAT) family 223 319 2.7E-9 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS22855 05047d19a3d20af9b1deef9c36d47659 335 Gene3D G3DSA:3.40.630.30 166 325 1.7E-23 T 28-03-2018 CU254_RS30285 db284619a1918615e733b98c8bf9f994 58 SUPERFAMILY SSF69047 2 55 1.1E-10 T 28-03-2018 IPR008462 CsbD-like domain CU254_RS30285 db284619a1918615e733b98c8bf9f994 58 Pfam PF05532 CsbD-like 3 54 3.6E-19 T 28-03-2018 IPR008462 CsbD-like domain CU254_RS30285 db284619a1918615e733b98c8bf9f994 58 Gene3D G3DSA:1.10.1470.10 1 58 2.7E-17 T 28-03-2018 IPR008462 CsbD-like domain CU254_RS01795 336557e2b1aa82a30f2893b470f26cb8 407 Pfam PF02470 MlaD protein 41 116 2.6E-18 T 28-03-2018 IPR003399 Mce/MlaD CU254_RS01795 336557e2b1aa82a30f2893b470f26cb8 407 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 162 283 1.2E-6 T 28-03-2018 IPR024516 Mammalian cell entry, C-terminal CU254_RS01795 336557e2b1aa82a30f2893b470f26cb8 407 Gene3D G3DSA:1.20.1170.10 99 338 4.2E-4 T 28-03-2018 CU254_RS01795 336557e2b1aa82a30f2893b470f26cb8 407 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 10 302 1.8E-67 T 28-03-2018 IPR005693 Virulence factor Mce protein CU254_RS19620 13e6896347e6709d85edf78e0c8661e5 416 Gene3D G3DSA:1.20.1250.20 6 205 1.1E-36 T 28-03-2018 CU254_RS19620 13e6896347e6709d85edf78e0c8661e5 416 Gene3D G3DSA:1.20.1250.20 207 404 9.0E-28 T 28-03-2018 CU254_RS19620 13e6896347e6709d85edf78e0c8661e5 416 SUPERFAMILY SSF103473 8 399 8.11E-82 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS19620 13e6896347e6709d85edf78e0c8661e5 416 Pfam PF07690 Major Facilitator Superfamily 24 365 1.2E-55 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS00200 a9d3ae6ceff80553fc770bddc76be091 248 Gene3D G3DSA:3.40.50.1820 2 248 2.3E-22 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS00200 a9d3ae6ceff80553fc770bddc76be091 248 PRINTS PR00412 Epoxide hydrolase signature 68 81 2.8E-6 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS00200 a9d3ae6ceff80553fc770bddc76be091 248 PRINTS PR00412 Epoxide hydrolase signature 221 243 2.8E-6 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS00200 a9d3ae6ceff80553fc770bddc76be091 248 PRINTS PR00412 Epoxide hydrolase signature 7 25 2.8E-6 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS00200 a9d3ae6ceff80553fc770bddc76be091 248 PRINTS PR00412 Epoxide hydrolase signature 82 95 2.8E-6 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS00200 a9d3ae6ceff80553fc770bddc76be091 248 SUPERFAMILY SSF53474 2 245 4.95E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS00200 a9d3ae6ceff80553fc770bddc76be091 248 Pfam PF12697 Alpha/beta hydrolase family 4 234 4.0E-16 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS19145 b0470405131ff6c76ffb31ac2154e784 378 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 291 306 1.2E-20 T 28-03-2018 CU254_RS19145 b0470405131ff6c76ffb31ac2154e784 378 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 1.2E-20 T 28-03-2018 CU254_RS19145 b0470405131ff6c76ffb31ac2154e784 378 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 306 322 1.2E-20 T 28-03-2018 CU254_RS19145 b0470405131ff6c76ffb31ac2154e784 378 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 149 164 1.2E-20 T 28-03-2018 CU254_RS19145 b0470405131ff6c76ffb31ac2154e784 378 Gene3D G3DSA:3.50.50.60 1 377 7.0E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS19145 b0470405131ff6c76ffb31ac2154e784 378 SUPERFAMILY SSF51905 1 170 2.21E-49 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS19145 b0470405131ff6c76ffb31ac2154e784 378 SUPERFAMILY SSF51905 276 365 2.21E-49 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS19145 b0470405131ff6c76ffb31ac2154e784 378 Pfam PF01494 FAD binding domain 3 167 2.2E-13 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CU254_RS19145 b0470405131ff6c76ffb31ac2154e784 378 Pfam PF01494 FAD binding domain 293 327 8.1E-9 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CU254_RS08290 f5f2e4078d9a214002a69584704cbd7d 201 Gene3D G3DSA:1.10.357.10 75 196 8.5E-13 T 28-03-2018 CU254_RS08290 f5f2e4078d9a214002a69584704cbd7d 201 Gene3D G3DSA:1.10.260.40 38 74 7.1E-4 T 28-03-2018 CU254_RS08290 f5f2e4078d9a214002a69584704cbd7d 201 SUPERFAMILY SSF46689 3 73 2.15E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS08290 f5f2e4078d9a214002a69584704cbd7d 201 Pfam PF14246 AefR-like transcriptional repressor, C-terminal region 147 193 1.8E-5 T 28-03-2018 CU254_RS08290 f5f2e4078d9a214002a69584704cbd7d 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 55 1.3E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS08290 f5f2e4078d9a214002a69584704cbd7d 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 3.4E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS08290 f5f2e4078d9a214002a69584704cbd7d 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 3.4E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS08290 f5f2e4078d9a214002a69584704cbd7d 201 Gene3D G3DSA:1.10.10.60 3 37 3.4E-14 T 28-03-2018 CU254_RS01540 5b030a86c5245652f4ccfa9019df0621 321 SUPERFAMILY SSF53448 30 248 6.75E-38 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS01540 5b030a86c5245652f4ccfa9019df0621 321 Gene3D G3DSA:3.90.550.10 10 313 1.2E-34 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS01540 5b030a86c5245652f4ccfa9019df0621 321 Pfam PF00535 Glycosyl transferase family 2 31 183 3.9E-20 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CU254_RS06525 b142d4ac5ed864cdcf509aeab5c73490 324 Pfam PF00704 Glycosyl hydrolases family 18 91 252 6.8E-10 T 28-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 CU254_RS06525 b142d4ac5ed864cdcf509aeab5c73490 324 SUPERFAMILY SSF51445 46 296 1.41E-18 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS06525 b142d4ac5ed864cdcf509aeab5c73490 324 Gene3D G3DSA:3.20.20.80 33 310 7.2E-22 T 28-03-2018 CU254_RS23490 f1fda369b68d91657a0594d5bff33b8c 144 Pfam PF14325 Domain of unknown function (DUF4383) 12 135 1.2E-45 T 28-03-2018 IPR025492 Protein of unknown function DUF4383 CU254_RS12365 1a58d245c02758f9249df8f50b17e8e0 235 Gene3D G3DSA:2.40.400.10 2 210 1.3E-8 T 28-03-2018 IPR023375 Acetoacetate decarboxylase beta barrel domain KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 CU254_RS12365 1a58d245c02758f9249df8f50b17e8e0 235 SUPERFAMILY SSF160104 7 167 5.89E-10 T 28-03-2018 IPR023375 Acetoacetate decarboxylase beta barrel domain KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 CU254_RS39205 aa9d84761d56648da348f04f874afe41 226 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 14 210 24.456 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CU254_RS39205 aa9d84761d56648da348f04f874afe41 226 Pfam PF02527 rRNA small subunit methyltransferase G 23 199 1.7E-50 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CU254_RS39205 aa9d84761d56648da348f04f874afe41 226 SUPERFAMILY SSF53335 20 216 1.72E-31 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS39205 aa9d84761d56648da348f04f874afe41 226 PIRSF PIRSF003078 3 216 1.5E-45 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CU254_RS39205 aa9d84761d56648da348f04f874afe41 226 Gene3D G3DSA:3.40.50.150 9 225 4.0E-31 T 28-03-2018 CU254_RS39205 aa9d84761d56648da348f04f874afe41 226 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 28 198 3.0E-40 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CU254_RS20960 caa6911fbad1e1410d4c773b514fa94c 123 Pfam PF01638 HxlR-like helix-turn-helix 23 113 4.8E-24 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type CU254_RS20960 caa6911fbad1e1410d4c773b514fa94c 123 Gene3D G3DSA:1.10.10.10 2 123 1.3E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS20960 caa6911fbad1e1410d4c773b514fa94c 123 SUPERFAMILY SSF46785 8 117 5.33E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS24890 9a36bb08a30ab27aaa56169acae945c2 167 SUPERFAMILY SSF55144 1 158 8.2E-29 T 28-03-2018 IPR009097 Cyclic phosphodiesterase CU254_RS24890 9a36bb08a30ab27aaa56169acae945c2 167 Gene3D G3DSA:3.90.1140.10 1 165 5.0E-31 T 28-03-2018 CU254_RS24890 9a36bb08a30ab27aaa56169acae945c2 167 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 1 154 8.8E-21 T 28-03-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 CU254_RS24890 9a36bb08a30ab27aaa56169acae945c2 167 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 1 157 17.464 T 28-03-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 CU254_RS24890 9a36bb08a30ab27aaa56169acae945c2 167 Pfam PF13563 2'-5' RNA ligase superfamily 9 143 1.7E-11 T 28-03-2018 CU254_RS21150 27ec0601cff58a42bde348bd73ab9ad0 800 Gene3D G3DSA:2.60.40.10 205 306 5.8E-9 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS21150 27ec0601cff58a42bde348bd73ab9ad0 800 Pfam PF00703 Glycosyl hydrolases family 2 208 315 2.0E-5 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 CU254_RS21150 27ec0601cff58a42bde348bd73ab9ad0 800 ProSitePatterns PS00608 Glycosyl hydrolases family 2 acid/base catalyst. 422 437 - T 28-03-2018 IPR023232 Glycoside hydrolase, family 2, active site KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 CU254_RS21150 27ec0601cff58a42bde348bd73ab9ad0 800 SUPERFAMILY SSF49785 57 204 7.51E-33 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS21150 27ec0601cff58a42bde348bd73ab9ad0 800 PRINTS PR00132 Glycosyl hydrolase family 2 signature 123 138 7.3E-11 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 CU254_RS21150 27ec0601cff58a42bde348bd73ab9ad0 800 PRINTS PR00132 Glycosyl hydrolase family 2 signature 326 340 7.3E-11 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 CU254_RS21150 27ec0601cff58a42bde348bd73ab9ad0 800 PRINTS PR00132 Glycosyl hydrolase family 2 signature 358 376 7.3E-11 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 CU254_RS21150 27ec0601cff58a42bde348bd73ab9ad0 800 PRINTS PR00132 Glycosyl hydrolase family 2 signature 422 437 7.3E-11 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 CU254_RS21150 27ec0601cff58a42bde348bd73ab9ad0 800 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 84 202 2.2E-13 T 28-03-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CU254_RS21150 27ec0601cff58a42bde348bd73ab9ad0 800 Gene3D G3DSA:2.60.40.10 696 799 9.2E-6 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS21150 27ec0601cff58a42bde348bd73ab9ad0 800 SUPERFAMILY SSF49373 695 788 1.6E-5 T 28-03-2018 IPR008964 Invasin/intimin cell-adhesion fragments CU254_RS21150 27ec0601cff58a42bde348bd73ab9ad0 800 SUPERFAMILY SSF51445 313 598 7.53E-56 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS21150 27ec0601cff58a42bde348bd73ab9ad0 800 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 324 462 8.6E-22 T 28-03-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 CU254_RS21150 27ec0601cff58a42bde348bd73ab9ad0 800 SUPERFAMILY SSF49303 207 314 5.76E-9 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 CU254_RS21150 27ec0601cff58a42bde348bd73ab9ad0 800 Gene3D G3DSA:3.20.20.80 307 632 1.6E-40 T 28-03-2018 CU254_RS21150 27ec0601cff58a42bde348bd73ab9ad0 800 Gene3D G3DSA:2.60.120.260 40 204 1.7E-29 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS04385 3d0a3e8bcd8e251e87fa2ca072d0d7b0 402 Gene3D G3DSA:3.40.190.10 165 344 1.8E-33 T 28-03-2018 CU254_RS04385 3d0a3e8bcd8e251e87fa2ca072d0d7b0 402 SUPERFAMILY SSF53850 54 400 8.0E-67 T 28-03-2018 CU254_RS04385 3d0a3e8bcd8e251e87fa2ca072d0d7b0 402 Pfam PF13416 Bacterial extracellular solute-binding protein 77 349 5.1E-28 T 28-03-2018 CU254_RS04385 3d0a3e8bcd8e251e87fa2ca072d0d7b0 402 Gene3D G3DSA:3.40.190.10 39 139 7.6E-4 T 28-03-2018 CU254_RS04385 3d0a3e8bcd8e251e87fa2ca072d0d7b0 402 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 83 104 3.5E-5 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CU254_RS04385 3d0a3e8bcd8e251e87fa2ca072d0d7b0 402 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 202 221 3.5E-5 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CU254_RS04385 3d0a3e8bcd8e251e87fa2ca072d0d7b0 402 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 157 173 3.5E-5 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CU254_RS04385 3d0a3e8bcd8e251e87fa2ca072d0d7b0 402 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 292 311 3.5E-5 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CU254_RS06025 c6ea6fe0ef96dff40148d262bedc53c1 300 Gene3D G3DSA:3.40.50.300 1 254 3.5E-55 T 28-03-2018 CU254_RS06025 c6ea6fe0ef96dff40148d262bedc53c1 300 SMART SM00382 29 205 2.5E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS06025 c6ea6fe0ef96dff40148d262bedc53c1 300 Pfam PF00005 ABC transporter 21 157 1.1E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS06025 c6ea6fe0ef96dff40148d262bedc53c1 300 SUPERFAMILY SSF52540 5 220 1.98E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS27630 a8975ec885457825f7674f2b6d166336 522 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 99 165 7.4E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS27630 a8975ec885457825f7674f2b6d166336 522 Pfam PF03752 Short repeats of unknown function 177 215 4.5E-9 T 28-03-2018 IPR005506 Protein of unknown function DUF312 CU254_RS16190 b64b97c3edb62777a5fe64b3f4f38092 266 Gene3D G3DSA:3.40.50.620 2 134 1.0E-26 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS16190 b64b97c3edb62777a5fe64b3f4f38092 266 Gene3D G3DSA:3.40.50.620 138 266 9.4E-17 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS16190 b64b97c3edb62777a5fe64b3f4f38092 266 SUPERFAMILY SSF52402 10 136 4.77E-24 T 28-03-2018 CU254_RS16190 b64b97c3edb62777a5fe64b3f4f38092 266 PRINTS PR01438 Universal stress protein signature 7 25 1.1E-12 T 28-03-2018 IPR006015 Universal stress protein A CU254_RS16190 b64b97c3edb62777a5fe64b3f4f38092 266 PRINTS PR01438 Universal stress protein signature 240 262 1.1E-12 T 28-03-2018 IPR006015 Universal stress protein A CU254_RS16190 b64b97c3edb62777a5fe64b3f4f38092 266 PRINTS PR01438 Universal stress protein signature 222 234 1.1E-12 T 28-03-2018 IPR006015 Universal stress protein A CU254_RS16190 b64b97c3edb62777a5fe64b3f4f38092 266 SUPERFAMILY SSF52402 151 262 3.52E-15 T 28-03-2018 CU254_RS16190 b64b97c3edb62777a5fe64b3f4f38092 266 Pfam PF00582 Universal stress protein family 9 134 6.2E-17 T 28-03-2018 IPR006016 UspA GO:0006950 CU254_RS16190 b64b97c3edb62777a5fe64b3f4f38092 266 Pfam PF00582 Universal stress protein family 143 262 2.9E-12 T 28-03-2018 IPR006016 UspA GO:0006950 CU254_RS08750 fb0540ab4802c3bfba6b61ee906b02d8 161 SMART SM00418 67 145 2.0E-4 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS08750 fb0540ab4802c3bfba6b61ee906b02d8 161 Pfam PF12840 Helix-turn-helix domain 66 126 2.6E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS08750 fb0540ab4802c3bfba6b61ee906b02d8 161 SUPERFAMILY SSF46785 66 138 3.83E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS08750 fb0540ab4802c3bfba6b61ee906b02d8 161 Gene3D G3DSA:1.10.10.10 61 145 1.7E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS07655 5907a59fa50d068c9712d803e3fa6364 342 Gene3D G3DSA:1.10.3470.10 49 334 8.2E-20 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CU254_RS07655 5907a59fa50d068c9712d803e3fa6364 342 Pfam PF02653 Branched-chain amino acid transport system / permease component 51 327 7.1E-51 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CU254_RS20965 aac26841923456e6907bb831458fd86f 402 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 29 381 2.0E-106 T 28-03-2018 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 CU254_RS20965 aac26841923456e6907bb831458fd86f 402 Pfam PF01098 Cell cycle protein 29 382 2.8E-100 T 28-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 CU254_RS20965 aac26841923456e6907bb831458fd86f 402 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 340 364 - T 28-03-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 CU254_RS12105 487662c3abcb8e4424888208660c1c65 860 SUPERFAMILY SSF158745 528 836 1.27E-20 T 28-03-2018 CU254_RS12105 487662c3abcb8e4424888208660c1c65 860 Gene3D G3DSA:3.30.200.20 230 316 7.3E-5 T 28-03-2018 CU254_RS12105 487662c3abcb8e4424888208660c1c65 860 Gene3D G3DSA:1.50.10.20 504 790 2.9E-4 T 28-03-2018 CU254_RS12105 487662c3abcb8e4424888208660c1c65 860 SMART SM01260 525 840 4.3E-5 T 28-03-2018 IPR007822 Lanthionine synthetase C-like CU254_RS12105 487662c3abcb8e4424888208660c1c65 860 SUPERFAMILY SSF56112 240 461 3.37E-25 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS12105 487662c3abcb8e4424888208660c1c65 860 SMART SM00220 238 524 3.3E-8 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CU254_RS12105 487662c3abcb8e4424888208660c1c65 860 Gene3D G3DSA:1.10.510.10 317 503 5.8E-18 T 28-03-2018 CU254_RS12105 487662c3abcb8e4424888208660c1c65 860 Gene3D G3DSA:3.30.2430.10 35 185 3.5E-31 T 28-03-2018 CU254_RS12105 487662c3abcb8e4424888208660c1c65 860 Pfam PF00069 Protein kinase domain 242 435 6.3E-15 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CU254_RS31655 2e18db3f2960e680d78ebfb20911a9c6 187 Gene3D G3DSA:3.40.50.150 4 174 5.6E-30 T 28-03-2018 CU254_RS31655 2e18db3f2960e680d78ebfb20911a9c6 187 Pfam PF13649 Methyltransferase domain 42 124 2.4E-15 T 28-03-2018 CU254_RS31655 2e18db3f2960e680d78ebfb20911a9c6 187 SUPERFAMILY SSF53335 5 134 1.72E-34 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS28495 eac1c8e7378219f743e487c536f8f460 204 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 19 204 1.6E-74 T 28-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 CU254_RS28495 eac1c8e7378219f743e487c536f8f460 204 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 22 204 1.4E-58 T 28-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 CU254_RS28495 eac1c8e7378219f743e487c536f8f460 204 Gene3D G3DSA:3.40.50.300 5 204 2.1E-63 T 28-03-2018 CU254_RS28495 eac1c8e7378219f743e487c536f8f460 204 SUPERFAMILY SSF52540 12 204 5.49E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS28495 eac1c8e7378219f743e487c536f8f460 204 PIRSF PIRSF015617 1 204 3.7E-64 T 28-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 CU254_RS22360 fbfa958122a00d46a1ba997b05295dc5 394 Gene3D G3DSA:3.40.50.10240 181 240 6.2E-4 T 28-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CU254_RS22360 fbfa958122a00d46a1ba997b05295dc5 394 SUPERFAMILY SSF63999 178 301 1.57E-16 T 28-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CU254_RS22360 fbfa958122a00d46a1ba997b05295dc5 394 Pfam PF12555 Thiamine pyrophosphokinase C terminal 335 386 9.9E-15 T 28-03-2018 IPR022215 Thiamine pyrophosphokinase C-terminal CU254_RS05090 402ffeda0bdd983258a4b621361b6f0a 319 Pfam PF02653 Branched-chain amino acid transport system / permease component 51 310 5.6E-41 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CU254_RS05090 402ffeda0bdd983258a4b621361b6f0a 319 Gene3D G3DSA:1.10.3470.10 35 316 2.9E-32 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CU254_RS02240 e3bb3d149dd405c3f617b15ce7554f67 480 SUPERFAMILY SSF64153 4 237 1.03E-49 T 28-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CU254_RS02240 e3bb3d149dd405c3f617b15ce7554f67 480 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 230 473 7.8E-45 T 28-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CU254_RS02240 e3bb3d149dd405c3f617b15ce7554f67 480 Pfam PF01256 Carbohydrate kinase 239 458 3.4E-52 T 28-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CU254_RS02240 e3bb3d149dd405c3f617b15ce7554f67 480 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 24 204 5.1E-30 T 28-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CU254_RS02240 e3bb3d149dd405c3f617b15ce7554f67 480 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 216 478 19.366 T 28-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CU254_RS02240 e3bb3d149dd405c3f617b15ce7554f67 480 Gene3D G3DSA:3.40.50.10260 3 214 6.8E-55 T 28-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CU254_RS02240 e3bb3d149dd405c3f617b15ce7554f67 480 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 416 426 - T 28-03-2018 IPR017953 Carbohydrate kinase, predicted, conserved site CU254_RS02240 e3bb3d149dd405c3f617b15ce7554f67 480 PIRSF PIRSF017184 3 479 3.1E-95 T 28-03-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 CU254_RS02240 e3bb3d149dd405c3f617b15ce7554f67 480 Gene3D G3DSA:3.40.1190.20 231 477 8.1E-45 T 28-03-2018 IPR029056 Ribokinase-like CU254_RS02240 e3bb3d149dd405c3f617b15ce7554f67 480 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 6 204 19.344 T 28-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CU254_RS02240 e3bb3d149dd405c3f617b15ce7554f67 480 SUPERFAMILY SSF53613 214 473 6.87E-57 T 28-03-2018 IPR029056 Ribokinase-like CU254_RS02240 e3bb3d149dd405c3f617b15ce7554f67 480 Pfam PF03853 YjeF-related protein N-terminus 25 184 8.5E-36 T 28-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CU254_RS16575 3da595273bbd86f76184f1db5efacff4 469 SUPERFAMILY SSF53335 278 433 4.18E-13 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS16575 3da595273bbd86f76184f1db5efacff4 469 TIGRFAM TIGR04074 bacter_Hen1: 3' terminal RNA ribose 2'-O-methyltransferase Hen1 2 465 7.5E-218 T 28-03-2018 IPR024026 3'-RNA ribose 2'-O-methyltransferase, Hen1, bacterial CU254_RS16575 3da595273bbd86f76184f1db5efacff4 469 Gene3D G3DSA:3.40.50.150 259 468 2.4E-29 T 28-03-2018 CU254_RS16575 3da595273bbd86f76184f1db5efacff4 469 Pfam PF12623 RNA repair, ligase-Pnkp-associating, region of Hen1 1 240 3.6E-115 T 28-03-2018 IPR024740 Hen1, N-terminal CU254_RS16575 3da595273bbd86f76184f1db5efacff4 469 Pfam PF08242 Methyltransferase domain 291 383 6.3E-9 T 28-03-2018 IPR013217 Methyltransferase type 12 CU254_RS19365 7d88d526d19b34ab30bff792e73294a5 342 SUPERFAMILY SSF51679 3 314 1.7E-56 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS19365 7d88d526d19b34ab30bff792e73294a5 342 Gene3D G3DSA:3.20.20.30 1 340 2.2E-56 T 28-03-2018 CU254_RS19365 7d88d526d19b34ab30bff792e73294a5 342 Pfam PF00296 Luciferase-like monooxygenase 13 309 1.1E-55 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS24920 f94e21f9beea27fa1aa044032b5a1ed9 445 Pfam PF01554 MatE 26 186 4.0E-28 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CU254_RS24920 f94e21f9beea27fa1aa044032b5a1ed9 445 Pfam PF01554 MatE 243 395 2.2E-14 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CU254_RS24920 f94e21f9beea27fa1aa044032b5a1ed9 445 PIRSF PIRSF006603 11 445 1.3E-49 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CU254_RS24920 f94e21f9beea27fa1aa044032b5a1ed9 445 TIGRFAM TIGR00797 matE: MATE efflux family protein 26 413 4.7E-92 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CU254_RS34500 61449a246074d7c7ee9e0c25b8c74ba0 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 7.4E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS34500 61449a246074d7c7ee9e0c25b8c74ba0 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 7.4E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS34500 61449a246074d7c7ee9e0c25b8c74ba0 207 Gene3D G3DSA:1.10.357.10 12 205 1.9E-24 T 28-03-2018 CU254_RS34500 61449a246074d7c7ee9e0c25b8c74ba0 207 SUPERFAMILY SSF46689 13 86 6.67E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS34500 61449a246074d7c7ee9e0c25b8c74ba0 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 65 8.8E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS40130 0823b50afcfd7152f0a104182d1c447e 221 Pfam PF14016 Protein of unknown function (DUF4232) 84 218 2.2E-34 T 28-03-2018 IPR025326 Protein of unknown function DUF4232 CU254_RS27390 5d25d88ebaf3766e66eadc1087f36809 422 Pfam PF00999 Sodium/hydrogen exchanger family 5 409 3.9E-28 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CU254_RS17470 86b33c0c9e89d849e1b80042b7e4cebd 331 SUPERFAMILY SSF53335 94 322 2.27E-49 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS17470 86b33c0c9e89d849e1b80042b7e4cebd 331 Gene3D G3DSA:1.10.10.10 3 94 1.2E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS17470 86b33c0c9e89d849e1b80042b7e4cebd 331 Gene3D G3DSA:3.40.50.150 95 330 6.0E-45 T 28-03-2018 CU254_RS17470 86b33c0c9e89d849e1b80042b7e4cebd 331 Pfam PF00891 O-methyltransferase 100 311 7.5E-41 T 28-03-2018 IPR001077 O-methyltransferase, family 2 GO:0008171 CU254_RS17470 86b33c0c9e89d849e1b80042b7e4cebd 331 PIRSF PIRSF005739 2 327 5.0E-52 T 28-03-2018 IPR016461 O-methyltransferase COMT-type GO:0008168 CU254_RS17470 86b33c0c9e89d849e1b80042b7e4cebd 331 SUPERFAMILY SSF46785 10 90 2.66E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS40625 334018b636d64ceb86e70e815ff04e87 352 Gene3D G3DSA:3.90.1150.10 245 350 6.4E-25 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS40625 334018b636d64ceb86e70e815ff04e87 352 Gene3D G3DSA:3.40.640.10 38 244 1.2E-41 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS40625 334018b636d64ceb86e70e815ff04e87 352 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 5 350 51.119 T 28-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CU254_RS40625 334018b636d64ceb86e70e815ff04e87 352 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 7 348 3.1E-91 T 28-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CU254_RS40625 334018b636d64ceb86e70e815ff04e87 352 Pfam PF00155 Aminotransferase class I and II 26 341 2.7E-51 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CU254_RS40625 334018b636d64ceb86e70e815ff04e87 352 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 214 223 - T 28-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 CU254_RS40625 334018b636d64ceb86e70e815ff04e87 352 Hamap MF_01513 Putative phenylalanine aminotransferase [pat]. 6 351 47.451 T 28-03-2018 IPR024892 Putative phenylalanine aminotransferase CU254_RS40625 334018b636d64ceb86e70e815ff04e87 352 SUPERFAMILY SSF53383 20 345 5.11E-81 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS39995 0f83713624b72db31b6e7f5fbeb5b5ee 194 Pfam PF01872 RibD C-terminal domain 4 187 1.6E-17 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CU254_RS39995 0f83713624b72db31b6e7f5fbeb5b5ee 194 SUPERFAMILY SSF53597 3 193 8.25E-21 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CU254_RS39995 0f83713624b72db31b6e7f5fbeb5b5ee 194 Gene3D G3DSA:3.40.430.10 2 191 1.3E-28 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CU254_RS03655 c8ececab0d5c639b6fd1fc5074ba2b5c 261 SUPERFAMILY SSF102405 48 250 4.43E-63 T 28-03-2018 CU254_RS03655 c8ececab0d5c639b6fd1fc5074ba2b5c 261 Pfam PF03641 Possible lysine decarboxylase 120 248 1.0E-31 T 28-03-2018 IPR031100 LOG family CU254_RS03655 c8ececab0d5c639b6fd1fc5074ba2b5c 261 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 78 252 7.0E-43 T 28-03-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG CU254_RS03655 c8ececab0d5c639b6fd1fc5074ba2b5c 261 Gene3D G3DSA:3.40.50.450 54 261 6.1E-69 T 28-03-2018 CU254_RS28355 e22524b2057fdc92a5a02afe426e23b4 170 SMART SM00347 48 150 4.2E-19 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS28355 e22524b2057fdc92a5a02afe426e23b4 170 Gene3D G3DSA:1.10.10.10 6 169 3.5E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS28355 e22524b2057fdc92a5a02afe426e23b4 170 SUPERFAMILY SSF46785 29 165 8.54E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS28355 e22524b2057fdc92a5a02afe426e23b4 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 110 126 2.3E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS28355 e22524b2057fdc92a5a02afe426e23b4 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 140 160 2.3E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS28355 e22524b2057fdc92a5a02afe426e23b4 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 91 106 2.3E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS28355 e22524b2057fdc92a5a02afe426e23b4 170 PRINTS PR00598 Bacterial regulatory protein MarR family signature 74 90 2.3E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS28355 e22524b2057fdc92a5a02afe426e23b4 170 Pfam PF12802 MarR family 53 114 9.0E-13 T 28-03-2018 CU254_RS10010 ac56666cfd60aff5603c9386851fd81c 153 Pfam PF01906 Putative heavy-metal-binding 12 114 3.2E-30 T 28-03-2018 IPR002765 Uncharacterised protein family UPF0145 CU254_RS10010 ac56666cfd60aff5603c9386851fd81c 153 Gene3D G3DSA:3.30.110.70 12 114 1.4E-29 T 28-03-2018 IPR035439 Uncharacterised protein family UPF0145/C2CD5 Reactome: R-HSA-1445148 CU254_RS10010 ac56666cfd60aff5603c9386851fd81c 153 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 12 114 20.677 T 28-03-2018 IPR002765 Uncharacterised protein family UPF0145 CU254_RS10010 ac56666cfd60aff5603c9386851fd81c 153 SUPERFAMILY SSF117782 13 115 1.44E-30 T 28-03-2018 IPR002765 Uncharacterised protein family UPF0145 CU254_RS21635 9ae131be639dc7eb9556d86bac3ea8fd 176 SUPERFAMILY SSF46785 3 149 9.12E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS21635 9ae131be639dc7eb9556d86bac3ea8fd 176 PRINTS PR00598 Bacterial regulatory protein MarR family signature 58 74 2.4E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS21635 9ae131be639dc7eb9556d86bac3ea8fd 176 PRINTS PR00598 Bacterial regulatory protein MarR family signature 125 145 2.4E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS21635 9ae131be639dc7eb9556d86bac3ea8fd 176 PRINTS PR00598 Bacterial regulatory protein MarR family signature 75 90 2.4E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS21635 9ae131be639dc7eb9556d86bac3ea8fd 176 PRINTS PR00598 Bacterial regulatory protein MarR family signature 94 110 2.4E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS21635 9ae131be639dc7eb9556d86bac3ea8fd 176 Pfam PF12802 MarR family 37 98 1.7E-14 T 28-03-2018 CU254_RS21635 9ae131be639dc7eb9556d86bac3ea8fd 176 Gene3D G3DSA:1.10.10.10 4 163 7.3E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS21635 9ae131be639dc7eb9556d86bac3ea8fd 176 SMART SM00347 32 135 8.1E-16 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS02830 e238c55807e4bf4f4e3de61005d37a71 365 Pfam PF02653 Branched-chain amino acid transport system / permease component 52 326 1.6E-32 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CU254_RS02830 e238c55807e4bf4f4e3de61005d37a71 365 Gene3D G3DSA:1.10.3470.10 5 337 6.4E-32 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CU254_RS35780 cb74348955cd7d8000fdbfe3d40efdd2 141 SUPERFAMILY SSF54909 1 119 6.97E-33 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS35780 cb74348955cd7d8000fdbfe3d40efdd2 141 Gene3D G3DSA:3.30.70.1060 1 119 2.0E-39 T 28-03-2018 CU254_RS35780 cb74348955cd7d8000fdbfe3d40efdd2 141 Pfam PF03795 YCII-related domain 1 115 2.2E-23 T 28-03-2018 IPR005545 YCII-related CU254_RS10110 2c72f81327a34ff316a55fff4420ebb2 389 Gene3D G3DSA:3.30.750.44 64 140 5.5E-12 T 28-03-2018 CU254_RS10110 2c72f81327a34ff316a55fff4420ebb2 389 Pfam PF03572 Peptidase family S41 186 368 5.7E-25 T 28-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 CU254_RS10110 2c72f81327a34ff316a55fff4420ebb2 389 SMART SM00245 152 369 9.6E-6 T 28-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 CU254_RS10110 2c72f81327a34ff316a55fff4420ebb2 389 Gene3D G3DSA:3.90.226.10 164 389 5.8E-34 T 28-03-2018 CU254_RS10110 2c72f81327a34ff316a55fff4420ebb2 389 SUPERFAMILY SSF52096 71 143 4.31E-35 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS10110 2c72f81327a34ff316a55fff4420ebb2 389 SUPERFAMILY SSF52096 176 388 4.31E-35 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS36900 407e8a8e8e21822f483b994f5c9e966b 382 Gene3D G3DSA:1.20.1250.20 180 375 9.0E-14 T 28-03-2018 CU254_RS36900 407e8a8e8e21822f483b994f5c9e966b 382 SUPERFAMILY SSF103473 2 367 1.22E-32 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS36900 407e8a8e8e21822f483b994f5c9e966b 382 Pfam PF07690 Major Facilitator Superfamily 2 245 6.4E-16 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS36900 407e8a8e8e21822f483b994f5c9e966b 382 Gene3D G3DSA:1.20.1250.20 1 178 1.0E-15 T 28-03-2018 CU254_RS08785 d766064d5591ce492f5205496e1a90f0 327 Pfam PF09346 SMI1 / KNR4 family (SUKH-1) 225 255 9.1E-7 T 28-03-2018 IPR018958 Knr4/Smi1-like domain CU254_RS08785 d766064d5591ce492f5205496e1a90f0 327 Gene3D G3DSA:3.40.1580.10 211 319 4.0E-9 T 28-03-2018 CU254_RS08785 d766064d5591ce492f5205496e1a90f0 327 SMART SM00860 225 318 9.0E-8 T 28-03-2018 IPR018958 Knr4/Smi1-like domain CU254_RS08785 d766064d5591ce492f5205496e1a90f0 327 SUPERFAMILY SSF160631 224 257 1.14E-7 T 28-03-2018 CU254_RS32490 9239ac10ce97cecc125341bc16e5d0dc 213 SUPERFAMILY SSF52540 2 199 5.65E-31 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS32490 9239ac10ce97cecc125341bc16e5d0dc 213 Pfam PF02223 Thymidylate kinase 7 186 1.4E-24 T 28-03-2018 CU254_RS32490 9239ac10ce97cecc125341bc16e5d0dc 213 Hamap MF_00165 Thymidylate kinase [tmk]. 3 212 12.993 T 28-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CU254_RS32490 9239ac10ce97cecc125341bc16e5d0dc 213 ProSitePatterns PS01331 Thymidylate kinase signature. 94 106 - T 28-03-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CU254_RS32490 9239ac10ce97cecc125341bc16e5d0dc 213 Gene3D G3DSA:3.40.50.300 4 205 3.9E-33 T 28-03-2018 CU254_RS39285 31c1a78d49a7169db9fcc6b4a8577bcb 256 Pfam PF01636 Phosphotransferase enzyme family 4 207 3.2E-22 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CU254_RS39285 31c1a78d49a7169db9fcc6b4a8577bcb 256 Gene3D G3DSA:1.10.510.10 30 236 1.4E-17 T 28-03-2018 CU254_RS39285 31c1a78d49a7169db9fcc6b4a8577bcb 256 SUPERFAMILY SSF56112 5 210 1.21E-28 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS20895 cc0b5aabe291354d71eb1e38f355b1f0 274 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 6 211 2.7E-31 T 28-03-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 CU254_RS20895 cc0b5aabe291354d71eb1e38f355b1f0 274 Gene3D G3DSA:3.20.20.360 1 250 6.7E-43 T 28-03-2018 CU254_RS20895 cc0b5aabe291354d71eb1e38f355b1f0 274 PIRSF PIRSF015582 1 274 5.6E-69 T 28-03-2018 IPR011206 Citrate lyase beta subunit-like CU254_RS20895 cc0b5aabe291354d71eb1e38f355b1f0 274 SUPERFAMILY SSF51621 6 223 3.84E-50 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CU254_RS42190 20166b811cfb68e574a0185cad975aa0 454 Pfam PF07812 TfuA-like protein 71 189 1.1E-41 T 28-03-2018 IPR012924 TfuA-like, core CU254_RS23925 2411c8be6203d409273bb0710266d5dd 292 Pfam PF00378 Enoyl-CoA hydratase/isomerase 20 79 8.7E-13 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CU254_RS23925 2411c8be6203d409273bb0710266d5dd 292 Pfam PF00378 Enoyl-CoA hydratase/isomerase 114 243 1.6E-26 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CU254_RS23925 2411c8be6203d409273bb0710266d5dd 292 Gene3D G3DSA:3.90.226.10 2 289 3.2E-64 T 28-03-2018 CU254_RS23925 2411c8be6203d409273bb0710266d5dd 292 SUPERFAMILY SSF52096 10 263 4.83E-68 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS29230 425c3e25fa322fed93be2c74ee8d97cc 226 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 69 9.3E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS29230 425c3e25fa322fed93be2c74ee8d97cc 226 Gene3D G3DSA:1.10.10.10 2 81 6.1E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS29230 425c3e25fa322fed93be2c74ee8d97cc 226 Pfam PF07729 FCD domain 103 216 1.3E-12 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS29230 425c3e25fa322fed93be2c74ee8d97cc 226 SMART SM00345 13 74 8.2E-4 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS29230 425c3e25fa322fed93be2c74ee8d97cc 226 SUPERFAMILY SSF48008 100 220 2.51E-11 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS29230 425c3e25fa322fed93be2c74ee8d97cc 226 SMART SM00895 99 219 2.2E-4 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS29230 425c3e25fa322fed93be2c74ee8d97cc 226 Gene3D G3DSA:1.20.120.530 94 223 3.3E-14 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS29230 425c3e25fa322fed93be2c74ee8d97cc 226 SUPERFAMILY SSF46785 5 87 2.08E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS37165 1b2cb0242a029bc7da813fe6d4fb509c 148 Gene3D G3DSA:2.30.110.10 29 139 3.0E-19 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS37165 1b2cb0242a029bc7da813fe6d4fb509c 148 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 35 114 4.4E-15 T 28-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CU254_RS37165 1b2cb0242a029bc7da813fe6d4fb509c 148 Pfam PF04075 F420H(2)-dependent quinone reductase 34 111 1.3E-8 T 28-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CU254_RS04460 4d35b420a0528000b2b5a895fb154b78 211 SUPERFAMILY SSF89392 25 194 5.49E-16 T 28-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX CU254_RS04460 4d35b420a0528000b2b5a895fb154b78 211 Pfam PF07161 LppX_LprAFG lipoprotein 28 189 6.3E-16 T 28-03-2018 IPR009830 LppX/LprAFG lipoprotein family CU254_RS04460 4d35b420a0528000b2b5a895fb154b78 211 ProDom PD017293 LIPOPROTEIN MEMBRANE PRECURSOR PALMITATE SIGNAL ANTIGEN LPRG LPPX P27 LPRA 25 186 3.0E-6 T 28-03-2018 IPR009830 LppX/LprAFG lipoprotein family CU254_RS11230 58a94ceb36011cd4d68196332692bbd7 201 Gene3D G3DSA:1.20.144.10 4 200 2.6E-10 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CU254_RS11230 58a94ceb36011cd4d68196332692bbd7 201 Pfam PF01569 PAP2 superfamily 117 188 1.1E-7 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CU254_RS11230 58a94ceb36011cd4d68196332692bbd7 201 SUPERFAMILY SSF48317 22 195 4.45E-14 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CU254_RS17625 db9f37e583a5e754a2fc202c5ca60402 392 SUPERFAMILY SSF51905 2 166 4.29E-63 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS17625 db9f37e583a5e754a2fc202c5ca60402 392 SUPERFAMILY SSF51905 266 366 4.29E-63 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS17625 db9f37e583a5e754a2fc202c5ca60402 392 Gene3D G3DSA:3.50.50.60 1 368 4.3E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS17625 db9f37e583a5e754a2fc202c5ca60402 392 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 279 294 2.3E-23 T 28-03-2018 CU254_RS17625 db9f37e583a5e754a2fc202c5ca60402 392 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 2.3E-23 T 28-03-2018 CU254_RS17625 db9f37e583a5e754a2fc202c5ca60402 392 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 145 160 2.3E-23 T 28-03-2018 CU254_RS17625 db9f37e583a5e754a2fc202c5ca60402 392 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 294 310 2.3E-23 T 28-03-2018 CU254_RS17625 db9f37e583a5e754a2fc202c5ca60402 392 Pfam PF01494 FAD binding domain 2 339 2.3E-29 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CU254_RS17625 db9f37e583a5e754a2fc202c5ca60402 392 SUPERFAMILY SSF54373 170 268 9.22E-17 T 28-03-2018 CU254_RS36450 4a5d6d144106817efb62ad85602cefe9 399 Gene3D G3DSA:3.40.50.300 8 183 8.6E-27 T 28-03-2018 CU254_RS36450 4a5d6d144106817efb62ad85602cefe9 399 Gene3D G3DSA:1.20.272.10 293 399 1.7E-27 T 28-03-2018 CU254_RS36450 4a5d6d144106817efb62ad85602cefe9 399 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 40 217 5.4E-57 T 28-03-2018 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CU254_RS36450 4a5d6d144106817efb62ad85602cefe9 399 SMART SM00382 42 183 2.1E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS36450 4a5d6d144106817efb62ad85602cefe9 399 Pfam PF13177 DNA polymerase III, delta subunit 41 181 2.1E-33 T 28-03-2018 CU254_RS36450 4a5d6d144106817efb62ad85602cefe9 399 SUPERFAMILY SSF52540 8 221 2.78E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS13750 8aa2fdb3bb40910303c31447d25a282d 412 SUPERFAMILY SSF88659 96 155 9.59E-9 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS13750 8aa2fdb3bb40910303c31447d25a282d 412 Pfam PF08281 Sigma-70, region 4 103 153 3.0E-9 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS13750 8aa2fdb3bb40910303c31447d25a282d 412 Pfam PF04542 Sigma-70 region 2 8 74 1.0E-10 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS13750 8aa2fdb3bb40910303c31447d25a282d 412 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 5 155 2.0E-12 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS13750 8aa2fdb3bb40910303c31447d25a282d 412 Gene3D G3DSA:1.25.40.120 164 402 6.4E-6 T 28-03-2018 CU254_RS13750 8aa2fdb3bb40910303c31447d25a282d 412 Gene3D G3DSA:1.10.1740.10 2 73 8.6E-17 T 28-03-2018 CU254_RS13750 8aa2fdb3bb40910303c31447d25a282d 412 Gene3D G3DSA:1.10.10.10 74 156 1.6E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS13750 8aa2fdb3bb40910303c31447d25a282d 412 SUPERFAMILY SSF88946 6 94 9.42E-14 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS12555 5cb4ddae16a6925577d712bb2cfa2344 989 Pfam PF13180 PDZ domain 790 855 2.8E-8 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CU254_RS12555 5cb4ddae16a6925577d712bb2cfa2344 989 Gene3D G3DSA:2.60.120.260 869 986 2.9E-14 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS12555 5cb4ddae16a6925577d712bb2cfa2344 989 SUPERFAMILY SSF50156 789 855 6.44E-13 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CU254_RS12555 5cb4ddae16a6925577d712bb2cfa2344 989 SUPERFAMILY SSF51126 312 667 1.31E-22 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor CU254_RS12555 5cb4ddae16a6925577d712bb2cfa2344 989 SUPERFAMILY SSF51126 81 132 1.31E-22 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor CU254_RS12555 5cb4ddae16a6925577d712bb2cfa2344 989 Pfam PF13229 Right handed beta helix region 347 513 7.4E-8 T 28-03-2018 CU254_RS12555 5cb4ddae16a6925577d712bb2cfa2344 989 SMART SM00228 731 849 3.6E-5 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CU254_RS12555 5cb4ddae16a6925577d712bb2cfa2344 989 Gene3D G3DSA:2.30.42.10 775 868 2.6E-14 T 28-03-2018 CU254_RS12555 5cb4ddae16a6925577d712bb2cfa2344 989 Gene3D G3DSA:2.160.20.10 23 745 5.7E-36 T 28-03-2018 IPR012334 Pectin lyase fold CU254_RS12555 5cb4ddae16a6925577d712bb2cfa2344 989 SMART SM00710 458 480 8.1 T 28-03-2018 IPR006626 Parallel beta-helix repeat CU254_RS12555 5cb4ddae16a6925577d712bb2cfa2344 989 SMART SM00710 483 510 9500.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CU254_RS12555 5cb4ddae16a6925577d712bb2cfa2344 989 SMART SM00710 551 573 2800.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CU254_RS12555 5cb4ddae16a6925577d712bb2cfa2344 989 SMART SM00710 377 419 3600.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CU254_RS12555 5cb4ddae16a6925577d712bb2cfa2344 989 SMART SM00710 353 375 8000.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CU254_RS12555 5cb4ddae16a6925577d712bb2cfa2344 989 SMART SM00710 310 352 7500.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CU254_RS12555 5cb4ddae16a6925577d712bb2cfa2344 989 SMART SM00710 430 457 1700.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CU254_RS28305 c6dcb74dd595062f3c07c970b819ddb2 518 TIGRFAM TIGR03173 pbuX: xanthine permease 88 494 6.9E-131 T 28-03-2018 IPR017588 Uric acid permease UacT-like GO:0006810|GO:0016021 CU254_RS28305 c6dcb74dd595062f3c07c970b819ddb2 518 Pfam PF00860 Permease family 85 459 4.6E-81 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CU254_RS28305 c6dcb74dd595062f3c07c970b819ddb2 518 SUPERFAMILY SSF103473 60 255 5.75E-6 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS28305 c6dcb74dd595062f3c07c970b819ddb2 518 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 81 493 1.5E-93 T 28-03-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CU254_RS10515 8d3b7e88c6d0f73bcda801c7e921145c 477 Pfam PF00474 Sodium:solute symporter family 33 392 7.7E-25 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CU254_RS10520 b78a53740523b3a7c36691f705048f25 400 Gene3D G3DSA:2.30.40.10 1 63 1.2E-18 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS10520 b78a53740523b3a7c36691f705048f25 400 Gene3D G3DSA:3.20.20.140 344 381 5.2E-5 T 28-03-2018 CU254_RS10520 b78a53740523b3a7c36691f705048f25 400 Gene3D G3DSA:3.20.20.140 64 343 3.8E-51 T 28-03-2018 CU254_RS10520 b78a53740523b3a7c36691f705048f25 400 SUPERFAMILY SSF51556 54 362 1.13E-95 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS10520 b78a53740523b3a7c36691f705048f25 400 SUPERFAMILY SSF51338 1 54 5.76E-19 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS10520 b78a53740523b3a7c36691f705048f25 400 SUPERFAMILY SSF51338 362 396 5.76E-19 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS10520 b78a53740523b3a7c36691f705048f25 400 Pfam PF01979 Amidohydrolase family 50 379 4.3E-45 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CU254_RS14430 959e6b78d6e510c6b8bd22d9a9908608 69 Gene3D G3DSA:3.20.20.70 18 69 4.3E-8 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS30240 e60ef2d9e9b084a345e90bede4fd487f 143 SUPERFAMILY SSF54909 67 142 3.62E-15 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS30240 e60ef2d9e9b084a345e90bede4fd487f 143 Pfam PF01037 Lrp/AsnC ligand binding domain 74 141 3.0E-13 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CU254_RS30240 e60ef2d9e9b084a345e90bede4fd487f 143 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 3.9E-11 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS30240 e60ef2d9e9b084a345e90bede4fd487f 143 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 3.9E-11 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS30240 e60ef2d9e9b084a345e90bede4fd487f 143 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 3.9E-11 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS30240 e60ef2d9e9b084a345e90bede4fd487f 143 SUPERFAMILY SSF46785 4 64 1.55E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS30240 e60ef2d9e9b084a345e90bede4fd487f 143 Gene3D G3DSA:3.30.70.920 57 143 1.1E-17 T 28-03-2018 CU254_RS30240 e60ef2d9e9b084a345e90bede4fd487f 143 SMART SM00344 5 111 8.4E-31 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CU254_RS30240 e60ef2d9e9b084a345e90bede4fd487f 143 Gene3D G3DSA:1.10.10.10 1 56 2.1E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS30240 e60ef2d9e9b084a345e90bede4fd487f 143 Pfam PF13412 Winged helix-turn-helix DNA-binding 5 52 1.8E-13 T 28-03-2018 CU254_RS17080 8bd2be4bcce643b51ae5c7d957ed5621 340 SUPERFAMILY SSF51679 9 336 1.06E-75 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS17080 8bd2be4bcce643b51ae5c7d957ed5621 340 TIGRFAM TIGR03554 F420_G6P_DH: glucose-6-phosphate dehydrogenase (coenzyme-F420) 9 336 3.2E-165 T 28-03-2018 IPR019944 F420-dependent glucose-6-phosphate dehydrogenase CU254_RS17080 8bd2be4bcce643b51ae5c7d957ed5621 340 TIGRFAM TIGR03557 F420_G6P_family: F420-dependent oxidoreductase, G6PDH family 10 337 2.7E-82 T 28-03-2018 IPR019945 F420-dependent glucose-6-phosphate dehydrogenase-related CU254_RS17080 8bd2be4bcce643b51ae5c7d957ed5621 340 Gene3D G3DSA:3.20.20.30 1 339 2.1E-78 T 28-03-2018 CU254_RS17080 8bd2be4bcce643b51ae5c7d957ed5621 340 Pfam PF00296 Luciferase-like monooxygenase 14 309 4.0E-69 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS41605 75eb2c99e59261165a617cfb95d8d48b 483 Pfam PF00990 Diguanylate cyclase, GGDEF domain 282 451 6.6E-35 T 28-03-2018 IPR000160 GGDEF domain CU254_RS41605 75eb2c99e59261165a617cfb95d8d48b 483 SMART SM00267 271 455 1.7E-35 T 28-03-2018 IPR000160 GGDEF domain CU254_RS41605 75eb2c99e59261165a617cfb95d8d48b 483 SUPERFAMILY SSF55073 288 453 1.18E-37 T 28-03-2018 IPR029787 Nucleotide cyclase CU254_RS41605 75eb2c99e59261165a617cfb95d8d48b 483 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 281 454 2.6E-38 T 28-03-2018 IPR000160 GGDEF domain CU254_RS41605 75eb2c99e59261165a617cfb95d8d48b 483 Gene3D G3DSA:3.30.70.270 272 456 1.8E-45 T 28-03-2018 CU254_RS22975 2a24275856b4d42484cda9e414dd784d 396 Pfam PF01548 Transposase 6 160 3.9E-45 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CU254_RS22975 2a24275856b4d42484cda9e414dd784d 396 Pfam PF02371 Transposase IS116/IS110/IS902 family 266 352 6.8E-17 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CU254_RS02515 167c4477c7319778c37dbd112367ec90 238 SMART SM00421 175 232 1.6E-25 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS02515 167c4477c7319778c37dbd112367ec90 238 Gene3D G3DSA:3.40.50.2300 24 150 9.6E-29 T 28-03-2018 CU254_RS02515 167c4477c7319778c37dbd112367ec90 238 SMART SM00448 25 139 2.9E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS02515 167c4477c7319778c37dbd112367ec90 238 SUPERFAMILY SSF52172 24 157 1.85E-28 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS02515 167c4477c7319778c37dbd112367ec90 238 Pfam PF00072 Response regulator receiver domain 27 139 4.3E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS02515 167c4477c7319778c37dbd112367ec90 238 Pfam PF00196 Bacterial regulatory proteins, luxR family 177 232 5.3E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS02515 167c4477c7319778c37dbd112367ec90 238 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 192 9.0E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS02515 167c4477c7319778c37dbd112367ec90 238 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 192 208 9.0E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS02515 167c4477c7319778c37dbd112367ec90 238 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 208 220 9.0E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS02515 167c4477c7319778c37dbd112367ec90 238 Gene3D G3DSA:1.10.10.10 151 238 2.5E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS02515 167c4477c7319778c37dbd112367ec90 238 SUPERFAMILY SSF46894 161 237 8.5E-23 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS02515 167c4477c7319778c37dbd112367ec90 238 ProSitePatterns PS00622 LuxR-type HTH domain signature. 192 219 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS22730 6819dfa551ed90e28aa81b2418847958 218 Pfam PF08808 RES domain 32 197 3.6E-22 T 28-03-2018 IPR014914 RES domain CU254_RS22730 6819dfa551ed90e28aa81b2418847958 218 SMART SM00953 60 190 4.2E-5 T 28-03-2018 IPR014914 RES domain CU254_RS35080 349ac225dfb6ca728b27311f5040bd67 268 PRINTS PR01543 Arylamine N-acetyltransferase signature 19 42 3.4E-19 T 28-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 CU254_RS35080 349ac225dfb6ca728b27311f5040bd67 268 PRINTS PR01543 Arylamine N-acetyltransferase signature 99 124 3.4E-19 T 28-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 CU254_RS35080 349ac225dfb6ca728b27311f5040bd67 268 PRINTS PR01543 Arylamine N-acetyltransferase signature 43 66 3.4E-19 T 28-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 CU254_RS35080 349ac225dfb6ca728b27311f5040bd67 268 PRINTS PR01543 Arylamine N-acetyltransferase signature 67 89 3.4E-19 T 28-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 CU254_RS35080 349ac225dfb6ca728b27311f5040bd67 268 Pfam PF00797 N-acetyltransferase 19 247 7.7E-63 T 28-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 CU254_RS35080 349ac225dfb6ca728b27311f5040bd67 268 SUPERFAMILY SSF54001 1 249 7.06E-69 T 28-03-2018 CU254_RS35080 349ac225dfb6ca728b27311f5040bd67 268 Gene3D G3DSA:3.30.2140.10 163 255 1.5E-15 T 28-03-2018 CU254_RS35080 349ac225dfb6ca728b27311f5040bd67 268 Gene3D G3DSA:3.30.2140.10 1 136 5.4E-43 T 28-03-2018 CU254_RS06910 0900ccbd23560a8d44f183b72d215522 277 Gene3D G3DSA:3.20.20.30 109 277 9.5E-13 T 28-03-2018 CU254_RS06910 0900ccbd23560a8d44f183b72d215522 277 SUPERFAMILY SSF51679 3 276 2.94E-35 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS06910 0900ccbd23560a8d44f183b72d215522 277 Gene3D G3DSA:3.20.20.30 1 108 2.8E-11 T 28-03-2018 CU254_RS06910 0900ccbd23560a8d44f183b72d215522 277 Pfam PF00296 Luciferase-like monooxygenase 124 252 1.3E-6 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS06910 0900ccbd23560a8d44f183b72d215522 277 Pfam PF00296 Luciferase-like monooxygenase 14 94 1.2E-11 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS06910 0900ccbd23560a8d44f183b72d215522 277 TIGRFAM TIGR03620 F420_MSMEG_4141: probable F420-dependent oxidoreductase, MSMEG_4141 family 2 275 1.6E-86 T 28-03-2018 IPR019922 Luciferase-like, F420-dependent oxidoreductase, MSMEG4141, predicted CU254_RS36870 87bf202a29d32905ccc1f4323a3d8c2a 463 SUPERFAMILY SSF53383 30 445 4.41E-132 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS36870 87bf202a29d32905ccc1f4323a3d8c2a 463 Gene3D G3DSA:3.40.640.10 73 323 2.0E-35 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS36870 87bf202a29d32905ccc1f4323a3d8c2a 463 TIGRFAM TIGR01788 Glu-decarb-GAD: glutamate decarboxylase 30 445 3.6E-191 T 28-03-2018 IPR010107 Glutamate decarboxylase GO:0004351|GO:0006536|GO:0030170 KEGG: 00250+4.1.1.15|KEGG: 00410+4.1.1.15|KEGG: 00430+4.1.1.15|KEGG: 00650+4.1.1.15|MetaCyc: PWY-4321 CU254_RS36870 87bf202a29d32905ccc1f4323a3d8c2a 463 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 52 378 3.0E-76 T 28-03-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 CU254_RS36870 87bf202a29d32905ccc1f4323a3d8c2a 463 Gene3D G3DSA:3.90.1150.10 324 447 6.5E-30 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS27415 6cd43e9b395920625aea2fe81e1e3d28 186 Gene3D G3DSA:1.10.260.40 44 64 1.9E-8 T 28-03-2018 CU254_RS27415 6cd43e9b395920625aea2fe81e1e3d28 186 Gene3D G3DSA:1.10.10.60 2 43 3.0E-11 T 28-03-2018 CU254_RS27415 6cd43e9b395920625aea2fe81e1e3d28 186 Gene3D G3DSA:1.10.357.10 65 186 1.4E-9 T 28-03-2018 CU254_RS27415 6cd43e9b395920625aea2fe81e1e3d28 186 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 61 1.2E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS27415 6cd43e9b395920625aea2fe81e1e3d28 186 SUPERFAMILY SSF46689 4 83 2.54E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS27415 6cd43e9b395920625aea2fe81e1e3d28 186 SUPERFAMILY SSF48498 81 182 1.06E-8 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS07110 954fd0649fb3fd0a87bf6bc6fb268b54 446 Gene3D G3DSA:1.20.1250.20 10 214 2.3E-39 T 28-03-2018 CU254_RS07110 954fd0649fb3fd0a87bf6bc6fb268b54 446 SUPERFAMILY SSF103473 7 438 1.22E-79 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS07110 954fd0649fb3fd0a87bf6bc6fb268b54 446 Pfam PF00083 Sugar (and other) transporter 25 440 8.7E-44 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CU254_RS07110 954fd0649fb3fd0a87bf6bc6fb268b54 446 Gene3D G3DSA:1.20.1250.20 237 446 5.3E-23 T 28-03-2018 CU254_RS07110 954fd0649fb3fd0a87bf6bc6fb268b54 446 ProSitePatterns PS00216 Sugar transport proteins signature 1. 73 89 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CU254_RS21205 3fc1a3320e6e49a496e02d7fdc946542 396 SUPERFAMILY SSF52266 198 395 5.04E-48 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CU254_RS21205 3fc1a3320e6e49a496e02d7fdc946542 396 Gene3D G3DSA:3.40.50.1110 193 391 3.2E-28 T 28-03-2018 CU254_RS21205 3fc1a3320e6e49a496e02d7fdc946542 396 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 204 386 3.7E-25 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CU254_RS07770 be7969ac494c0ab76ff72efc263cb42e 160 Pfam PF13302 Acetyltransferase (GNAT) domain 3 130 5.1E-16 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS07770 be7969ac494c0ab76ff72efc263cb42e 160 Gene3D G3DSA:3.40.630.30 2 160 1.2E-33 T 28-03-2018 CU254_RS07770 be7969ac494c0ab76ff72efc263cb42e 160 SUPERFAMILY SSF55729 2 155 1.26E-32 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS01405 21ea47b4680e5064d3d0f0e82a57933b 524 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 19 514 17.472 T 28-03-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 CU254_RS01405 21ea47b4680e5064d3d0f0e82a57933b 524 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 22 513 6.6E-111 T 28-03-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 CU254_RS01405 21ea47b4680e5064d3d0f0e82a57933b 524 Pfam PF00361 Proton-conducting membrane transporter 166 460 5.3E-72 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS12145 7b8a9ad0738de00fa53e618f56daf1eb 206 PRINTS PR01217 Proline rich extensin signature 65 77 4.7E-10 T 28-03-2018 CU254_RS12145 7b8a9ad0738de00fa53e618f56daf1eb 206 PRINTS PR01217 Proline rich extensin signature 43 59 4.7E-10 T 28-03-2018 CU254_RS12145 7b8a9ad0738de00fa53e618f56daf1eb 206 PRINTS PR01217 Proline rich extensin signature 122 139 4.7E-10 T 28-03-2018 CU254_RS12145 7b8a9ad0738de00fa53e618f56daf1eb 206 PRINTS PR01217 Proline rich extensin signature 79 100 4.7E-10 T 28-03-2018 CU254_RS12145 7b8a9ad0738de00fa53e618f56daf1eb 206 PRINTS PR01217 Proline rich extensin signature 105 121 4.7E-10 T 28-03-2018 CU254_RS26605 495055730f66a060fb3f3e945046e6e5 306 TIGRFAM TIGR02039 CysD: sulfate adenylyltransferase, small subunit 15 306 4.8E-140 T 28-03-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 CU254_RS26605 495055730f66a060fb3f3e945046e6e5 306 PIRSF PIRSF002936 7 306 4.8E-134 T 28-03-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 CU254_RS26605 495055730f66a060fb3f3e945046e6e5 306 Gene3D G3DSA:3.40.50.620 9 273 6.3E-40 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS26605 495055730f66a060fb3f3e945046e6e5 306 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 36 260 8.0E-46 T 28-03-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 CU254_RS26605 495055730f66a060fb3f3e945046e6e5 306 SUPERFAMILY SSF52402 10 213 2.09E-64 T 28-03-2018 CU254_RS05515 8ebed2d0aafae5fe04a0680b3098d0a6 146 SUPERFAMILY SSF82607 26 111 2.75E-7 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CU254_RS05515 8ebed2d0aafae5fe04a0680b3098d0a6 146 Gene3D G3DSA:3.30.1310.10 15 113 1.4E-18 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CU254_RS05515 8ebed2d0aafae5fe04a0680b3098d0a6 146 Pfam PF02575 YbaB/EbfC DNA-binding family 26 111 4.5E-10 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CU254_RS02165 48e49a13d7ae2b0af08afca52d670fca 1337 Gene3D G3DSA:3.40.50.300 446 662 4.0E-18 T 28-03-2018 CU254_RS02165 48e49a13d7ae2b0af08afca52d670fca 1337 Gene3D G3DSA:3.40.50.300 742 1026 2.5E-16 T 28-03-2018 CU254_RS02165 48e49a13d7ae2b0af08afca52d670fca 1337 Gene3D G3DSA:3.40.50.300 1075 1294 0.093 T 28-03-2018 CU254_RS02165 48e49a13d7ae2b0af08afca52d670fca 1337 TIGRFAM TIGR03924 T7SS_EccC_a: type VII secretion protein EccCa 24 699 8.6E-286 T 28-03-2018 IPR023836 EccCa-like, Actinobacteria CU254_RS02165 48e49a13d7ae2b0af08afca52d670fca 1337 SUPERFAMILY SSF52540 1078 1266 1.1E-6 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS02165 48e49a13d7ae2b0af08afca52d670fca 1337 TIGRFAM TIGR03925 T7SS_EccC_b: type VII secretion protein EccCb 759 1331 4.7E-233 T 28-03-2018 IPR023837 EccCb-like, Actinobacteria CU254_RS02165 48e49a13d7ae2b0af08afca52d670fca 1337 SUPERFAMILY SSF52540 441 700 1.35E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS02165 48e49a13d7ae2b0af08afca52d670fca 1337 Pfam PF01580 FtsK/SpoIIIE family 816 1053 2.5E-53 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CU254_RS02165 48e49a13d7ae2b0af08afca52d670fca 1337 Pfam PF01580 FtsK/SpoIIIE family 450 567 4.9E-23 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CU254_RS02165 48e49a13d7ae2b0af08afca52d670fca 1337 SUPERFAMILY SSF52540 776 1029 1.76E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS28165 641f81f10ed29a6975a1843d0ca042a7 313 Gene3D G3DSA:1.10.260.40 15 93 2.4E-6 T 28-03-2018 CU254_RS13115 af2aad72bca3c2a223585fe5fbebc664 195 Gene3D G3DSA:2.60.120.200 46 194 1.8E-9 T 28-03-2018 CU254_RS33225 2655cc7c5176eb44bd07e31a525bb5df 175 SUPERFAMILY SSF55166 55 158 1.88E-22 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CU254_RS33225 2655cc7c5176eb44bd07e31a525bb5df 175 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 56 150 7.4E-11 T 28-03-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 CU254_RS33225 2655cc7c5176eb44bd07e31a525bb5df 175 Gene3D G3DSA:3.30.1380.10 52 158 8.9E-18 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CU254_RS38335 9e03c86359ba1f60fc084eee1fd0d896 179 Pfam PF01161 Phosphatidylethanolamine-binding protein 39 175 3.8E-38 T 28-03-2018 IPR008914 Phosphatidylethanolamine-binding protein CU254_RS38335 9e03c86359ba1f60fc084eee1fd0d896 179 SUPERFAMILY SSF49777 19 177 1.31E-51 T 28-03-2018 IPR008914 Phosphatidylethanolamine-binding protein CU254_RS38335 9e03c86359ba1f60fc084eee1fd0d896 179 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 41 175 1.5E-38 T 28-03-2018 IPR005247 YbhB/YbcL CU254_RS38335 9e03c86359ba1f60fc084eee1fd0d896 179 Gene3D G3DSA:3.90.280.10 2 178 1.5E-53 T 28-03-2018 IPR008914 Phosphatidylethanolamine-binding protein CU254_RS06575 5de507b199d61cd48fa29d363ef81a2b 301 Pfam PF02627 Carboxymuconolactone decarboxylase family 40 109 2.6E-10 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CU254_RS06575 5de507b199d61cd48fa29d363ef81a2b 301 SUPERFAMILY SSF69118 6 170 7.2E-31 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CU254_RS06575 5de507b199d61cd48fa29d363ef81a2b 301 Gene3D G3DSA:1.20.1290.10 29 176 2.3E-29 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CU254_RS06515 6774f30c0f09fcab8b19d6eba9b5b415 402 Gene3D G3DSA:3.40.50.150 81 259 1.1E-18 T 28-03-2018 CU254_RS06515 6774f30c0f09fcab8b19d6eba9b5b415 402 SUPERFAMILY SSF53335 83 189 4.22E-9 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS17900 c78f2a790a3c3c6877a227e892c314ed 110 Gene3D G3DSA:1.10.287.1060 5 109 3.6E-5 T 28-03-2018 CU254_RS34480 4dfc1f05d56bf77225a49b3ecf6ece4f 1350 Gene3D G3DSA:3.40.50.300 1082 1314 1.0E-5 T 28-03-2018 CU254_RS34480 4dfc1f05d56bf77225a49b3ecf6ece4f 1350 Gene3D G3DSA:3.40.50.300 25 389 7.1E-6 T 28-03-2018 CU254_RS34480 4dfc1f05d56bf77225a49b3ecf6ece4f 1350 SUPERFAMILY SSF52540 39 71 4.11E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS34480 4dfc1f05d56bf77225a49b3ecf6ece4f 1350 SUPERFAMILY SSF52540 1100 1301 4.11E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS34480 4dfc1f05d56bf77225a49b3ecf6ece4f 1350 Pfam PF13558 Putative exonuclease SbcCD, C subunit 1208 1294 3.8E-19 T 28-03-2018 CU254_RS34480 4dfc1f05d56bf77225a49b3ecf6ece4f 1350 Gene3D G3DSA:1.20.1170.10 524 962 2.5E-11 T 28-03-2018 CU254_RS34480 4dfc1f05d56bf77225a49b3ecf6ece4f 1350 TIGRFAM TIGR02680 TIGR02680: TIGR02680 family protein 20 1343 0.0 T 28-03-2018 IPR013496 Conserved hypothetical protein CHP02680 CU254_RS34480 4dfc1f05d56bf77225a49b3ecf6ece4f 1350 SUPERFAMILY SSF52540 307 343 9.65E-9 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS34480 4dfc1f05d56bf77225a49b3ecf6ece4f 1350 SUPERFAMILY SSF52540 448 527 9.65E-9 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS34480 4dfc1f05d56bf77225a49b3ecf6ece4f 1350 SUPERFAMILY SSF52540 30 233 9.65E-9 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS27890 55dcd258f63133731274a968e5a921f9 68 SUPERFAMILY SSF55008 2 67 1.7E-18 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CU254_RS27890 55dcd258f63133731274a968e5a921f9 68 ProSitePatterns PS01047 Heavy-metal-associated domain. 8 37 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CU254_RS27890 55dcd258f63133731274a968e5a921f9 68 Pfam PF00403 Heavy-metal-associated domain 5 65 4.2E-15 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CU254_RS27890 55dcd258f63133731274a968e5a921f9 68 PRINTS PR00944 Copper ion binding protein signature 3 15 1.5E-10 T 28-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CU254_RS27890 55dcd258f63133731274a968e5a921f9 68 PRINTS PR00944 Copper ion binding protein signature 41 53 1.5E-10 T 28-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CU254_RS27890 55dcd258f63133731274a968e5a921f9 68 PRINTS PR00944 Copper ion binding protein signature 28 41 1.5E-10 T 28-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CU254_RS27890 55dcd258f63133731274a968e5a921f9 68 PRINTS PR00944 Copper ion binding protein signature 15 28 1.5E-10 T 28-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CU254_RS27890 55dcd258f63133731274a968e5a921f9 68 PRINTS PR00944 Copper ion binding protein signature 53 66 1.5E-10 T 28-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CU254_RS27890 55dcd258f63133731274a968e5a921f9 68 Gene3D G3DSA:3.30.70.100 2 67 2.8E-19 T 28-03-2018 CU254_RS27890 55dcd258f63133731274a968e5a921f9 68 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 5 67 9.2E-18 T 28-03-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 CU254_RS18560 d8f5727388d971057873aa108a2d7e15 148 Pfam PF00571 CBS domain 98 143 3.6E-4 T 28-03-2018 IPR000644 CBS domain CU254_RS18560 d8f5727388d971057873aa108a2d7e15 148 SUPERFAMILY SSF54631 2 142 1.64E-13 T 28-03-2018 CU254_RS18560 d8f5727388d971057873aa108a2d7e15 148 Gene3D G3DSA:3.10.580.10 2 147 2.1E-15 T 28-03-2018 CU254_RS15960 f6125bf93d7678d7699b336293548ba4 137 Gene3D G3DSA:2.60.40.230 34 129 6.8E-11 T 28-03-2018 CU254_RS15960 f6125bf93d7678d7699b336293548ba4 137 SUPERFAMILY SSF49319 36 137 6.8E-13 T 28-03-2018 IPR027273 Neocarzinostatin-like CU254_RS15960 f6125bf93d7678d7699b336293548ba4 137 Pfam PF00960 Neocarzinostatin family 37 136 1.1E-10 T 28-03-2018 IPR002186 Neocarzinostatin family GO:0003677|GO:0006952 CU254_RS20765 eb04a26f92639c3eb936aa096de2a1cc 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 255 4.6E-50 T 28-03-2018 CU254_RS20765 eb04a26f92639c3eb936aa096de2a1cc 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.0E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS20765 eb04a26f92639c3eb936aa096de2a1cc 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 220 240 2.0E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS20765 eb04a26f92639c3eb936aa096de2a1cc 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 2.0E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS20765 eb04a26f92639c3eb936aa096de2a1cc 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 2.0E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS20765 eb04a26f92639c3eb936aa096de2a1cc 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 2.0E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS20765 eb04a26f92639c3eb936aa096de2a1cc 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 2.0E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS20765 eb04a26f92639c3eb936aa096de2a1cc 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 3.5E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS20765 eb04a26f92639c3eb936aa096de2a1cc 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 3.5E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS20765 eb04a26f92639c3eb936aa096de2a1cc 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 3.5E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS20765 eb04a26f92639c3eb936aa096de2a1cc 259 Gene3D G3DSA:3.40.50.720 1 258 1.1E-62 T 28-03-2018 CU254_RS20765 eb04a26f92639c3eb936aa096de2a1cc 259 SUPERFAMILY SSF51735 6 256 1.45E-69 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS36745 ff7bcb69d14c5c8cd92f09f6b19d54f8 238 SUPERFAMILY SSF55811 31 201 4.2E-29 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CU254_RS36745 ff7bcb69d14c5c8cd92f09f6b19d54f8 238 Gene3D G3DSA:3.90.79.10 24 205 1.8E-35 T 28-03-2018 CU254_RS36745 ff7bcb69d14c5c8cd92f09f6b19d54f8 238 Pfam PF00293 NUDIX domain 42 161 6.4E-14 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CU254_RS18170 922f06decfbb1b384c30a92c581ce8ad 296 Pfam PF12705 PD-(D/E)XK nuclease superfamily 23 269 1.2E-36 T 28-03-2018 CU254_RS18170 922f06decfbb1b384c30a92c581ce8ad 296 SUPERFAMILY SSF52980 50 205 3.38E-9 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CU254_RS18170 922f06decfbb1b384c30a92c581ce8ad 296 Gene3D G3DSA:3.90.320.10 2 221 3.2E-26 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 CU254_RS16065 a4ced02998c8df2b51176b5c8a355e1c 107 SUPERFAMILY SSF103481 6 105 6.67E-19 T 28-03-2018 CU254_RS16065 a4ced02998c8df2b51176b5c8a355e1c 107 Pfam PF00893 Small Multidrug Resistance protein 1 93 5.0E-22 T 28-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 CU254_RS39890 48dd5781ebb910729f7ad4680de45f6a 133 Pfam PF15585 Immunity protein 7 2 129 1.2E-46 T 28-03-2018 IPR028965 Immunity protein 7 CU254_RS27435 c51a26ae5c0efcb6bdfd960113f8a8c2 293 Gene3D G3DSA:3.90.1200.10 109 288 7.0E-10 T 28-03-2018 CU254_RS27435 c51a26ae5c0efcb6bdfd960113f8a8c2 293 SUPERFAMILY SSF56112 10 262 2.24E-14 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS22375 3a8fe0bedd6fbc50c3fbd2b06f5c2725 306 SUPERFAMILY SSF111331 6 299 1.7E-74 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain CU254_RS22375 3a8fe0bedd6fbc50c3fbd2b06f5c2725 306 Hamap MF_00361 NAD kinase [nadK]. 5 293 28.764 T 28-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CU254_RS22375 3a8fe0bedd6fbc50c3fbd2b06f5c2725 306 Pfam PF01513 ATP-NAD kinase 7 278 4.9E-57 T 28-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CU254_RS22375 3a8fe0bedd6fbc50c3fbd2b06f5c2725 306 Gene3D G3DSA:2.60.200.30 148 269 2.0E-34 T 28-03-2018 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CU254_RS22375 3a8fe0bedd6fbc50c3fbd2b06f5c2725 306 Gene3D G3DSA:3.40.50.10330 2 147 2.4E-33 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 CU254_RS41875 ac9f90b78e93cf3ab117b850f120f003 250 ProDom PD038511 GENE GP88 GP85 PAE1962 46 139 2.0E-6 T 28-03-2018 IPR020290 Protein of unknown function, Gp85/88 CU254_RS41875 ac9f90b78e93cf3ab117b850f120f003 250 Pfam PF17338 Gene 88 protein 15 245 3.8E-127 T 28-03-2018 IPR020290 Protein of unknown function, Gp85/88 CU254_RS18025 d97065ffc21ca402ff54d3e8e41c62a8 264 PRINTS PR00111 Alpha/beta hydrolase fold signature 88 101 1.1E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS18025 d97065ffc21ca402ff54d3e8e41c62a8 264 PRINTS PR00111 Alpha/beta hydrolase fold signature 200 214 1.1E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS18025 d97065ffc21ca402ff54d3e8e41c62a8 264 PRINTS PR00111 Alpha/beta hydrolase fold signature 102 115 1.1E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS18025 d97065ffc21ca402ff54d3e8e41c62a8 264 PRINTS PR00111 Alpha/beta hydrolase fold signature 44 59 1.1E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS18025 d97065ffc21ca402ff54d3e8e41c62a8 264 Gene3D G3DSA:3.40.50.1820 1 255 7.0E-44 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS18025 d97065ffc21ca402ff54d3e8e41c62a8 264 SUPERFAMILY SSF53474 9 254 2.41E-48 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS18025 d97065ffc21ca402ff54d3e8e41c62a8 264 Pfam PF12697 Alpha/beta hydrolase family 22 250 1.6E-17 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS09380 9c8fa96470ab7d1c501e89d84d73b58d 596 Gene3D G3DSA:1.10.287.700 404 559 1.4E-5 T 28-03-2018 CU254_RS25520 a1a8c86b000290a967014f9c699ffe21 309 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 278 293 3.1E-7 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CU254_RS25520 a1a8c86b000290a967014f9c699ffe21 309 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 293 309 3.1E-7 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CU254_RS25520 a1a8c86b000290a967014f9c699ffe21 309 SUPERFAMILY SSF46689 261 309 6.72E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS25520 a1a8c86b000290a967014f9c699ffe21 309 Gene3D G3DSA:1.10.10.60 263 309 6.5E-13 T 28-03-2018 CU254_RS25520 a1a8c86b000290a967014f9c699ffe21 309 Gene3D G3DSA:1.10.10.60 205 262 5.8E-8 T 28-03-2018 CU254_RS25520 a1a8c86b000290a967014f9c699ffe21 309 Pfam PF12833 Helix-turn-helix domain 231 309 1.7E-24 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS25520 a1a8c86b000290a967014f9c699ffe21 309 SMART SM00342 225 309 2.7E-28 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS25520 a1a8c86b000290a967014f9c699ffe21 309 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 262 305 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CU254_RS25520 a1a8c86b000290a967014f9c699ffe21 309 Pfam PF14525 AraC-binding-like domain 18 193 1.7E-29 T 28-03-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like CU254_RS04235 1b9552bb31c0eed031f0e4e1631bb738 299 Pfam PF03186 CobD/Cbib protein 9 273 5.3E-43 T 28-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 CU254_RS04235 1b9552bb31c0eed031f0e4e1631bb738 299 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 295 49.176 T 28-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 CU254_RS19635 97a5eea21749bf41147d9b932c7d2fed 280 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 6 259 1.1E-76 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CU254_RS19635 97a5eea21749bf41147d9b932c7d2fed 280 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 1 266 17.211 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CU254_RS19635 97a5eea21749bf41147d9b932c7d2fed 280 Pfam PF02673 Bacitracin resistance protein BacA 6 261 9.2E-81 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CU254_RS15640 76b2611a2cbdeb7258d5d262383b7235 326 SMART SM01236 159 264 1.5E-30 T 28-03-2018 CU254_RS15640 76b2611a2cbdeb7258d5d262383b7235 326 Gene3D G3DSA:1.20.910.10 117 325 1.3E-23 T 28-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CU254_RS15640 76b2611a2cbdeb7258d5d262383b7235 326 Pfam PF14518 Iron-containing redox enzyme 127 299 2.4E-41 T 28-03-2018 IPR028201 PqqC-like protein CU254_RS15640 76b2611a2cbdeb7258d5d262383b7235 326 SUPERFAMILY SSF48613 125 298 9.78E-7 T 28-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CU254_RS26965 b0bf7cfc8990eb63496bc347ecc4c6df 140 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 128 6.0E-8 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CU254_RS26965 b0bf7cfc8990eb63496bc347ecc4c6df 140 Gene3D G3DSA:3.10.180.10 1 138 6.8E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS26965 b0bf7cfc8990eb63496bc347ecc4c6df 140 SUPERFAMILY SSF54593 7 136 5.1E-23 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS04185 f71fde7c44d6b6ccd2d7121813b60482 458 Gene3D G3DSA:3.40.190.10 53 256 6.8E-32 T 28-03-2018 CU254_RS04185 f71fde7c44d6b6ccd2d7121813b60482 458 Gene3D G3DSA:3.40.190.10 257 409 1.6E-9 T 28-03-2018 CU254_RS04185 f71fde7c44d6b6ccd2d7121813b60482 458 Pfam PF13416 Bacterial extracellular solute-binding protein 73 395 1.2E-27 T 28-03-2018 CU254_RS04185 f71fde7c44d6b6ccd2d7121813b60482 458 SUPERFAMILY SSF53850 31 454 1.93E-62 T 28-03-2018 CU254_RS10985 20a4629e04bd51f087f69c5d885c494e 483 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 393 413 - T 28-03-2018 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 CU254_RS10985 20a4629e04bd51f087f69c5d885c494e 483 Pfam PF00474 Sodium:solute symporter family 32 411 8.3E-38 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CU254_RS07285 06d5d27ee4825fd2758736ccccff2f2a 257 Pfam PF02405 Permease MlaE 36 246 1.1E-65 T 28-03-2018 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 CU254_RS12890 dd236f03fdd4dfe6e8a0b7c350931752 331 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 2 325 1.2E-88 T 28-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CU254_RS12890 dd236f03fdd4dfe6e8a0b7c350931752 331 SUPERFAMILY SSF53901 4 326 9.84E-57 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS12890 dd236f03fdd4dfe6e8a0b7c350931752 331 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 237 325 1.7E-23 T 28-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CU254_RS12890 dd236f03fdd4dfe6e8a0b7c350931752 331 Gene3D G3DSA:3.40.47.10 1 160 7.0E-32 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS12890 dd236f03fdd4dfe6e8a0b7c350931752 331 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 106 184 9.7E-26 T 28-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CU254_RS12890 dd236f03fdd4dfe6e8a0b7c350931752 331 Gene3D G3DSA:3.40.47.10 161 330 1.2E-35 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS17175 34fe8849c497be77bfb6cb3a8fa32f8a 283 Gene3D G3DSA:3.50.50.60 17 270 0.0016 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS27695 51a909bf69b493c67d37b4bcbb51f597 362 SUPERFAMILY SSF53474 55 203 6.49E-32 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS27695 51a909bf69b493c67d37b4bcbb51f597 362 SUPERFAMILY SSF53474 255 333 6.49E-32 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS27695 51a909bf69b493c67d37b4bcbb51f597 362 Gene3D G3DSA:3.40.50.1820 6 362 9.0E-39 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS27695 51a909bf69b493c67d37b4bcbb51f597 362 Pfam PF00756 Putative esterase 66 354 8.4E-28 T 28-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 CU254_RS24790 ff2a326394a9a48325a6398a8c54128f 314 Pfam PF00892 EamA-like transporter family 18 152 5.7E-20 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CU254_RS24790 ff2a326394a9a48325a6398a8c54128f 314 Pfam PF00892 EamA-like transporter family 165 306 1.3E-21 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CU254_RS24790 ff2a326394a9a48325a6398a8c54128f 314 SUPERFAMILY SSF103481 224 309 2.35E-15 T 28-03-2018 CU254_RS24790 ff2a326394a9a48325a6398a8c54128f 314 SUPERFAMILY SSF103481 54 154 1.96E-13 T 28-03-2018 CU254_RS09460 2f9c339d9e98b522151e9627cd9465d9 363 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 93 107 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site CU254_RS09460 2f9c339d9e98b522151e9627cd9465d9 363 SUPERFAMILY SSF48576 17 362 2.06E-69 T 28-03-2018 IPR008949 Isoprenoid synthase domain CU254_RS09460 2f9c339d9e98b522151e9627cd9465d9 363 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 237 249 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site CU254_RS09460 2f9c339d9e98b522151e9627cd9465d9 363 Gene3D G3DSA:1.10.600.10 7 363 4.7E-83 T 28-03-2018 IPR008949 Isoprenoid synthase domain CU254_RS09460 2f9c339d9e98b522151e9627cd9465d9 363 Pfam PF00348 Polyprenyl synthetase 46 285 1.3E-44 T 28-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 CU254_RS40990 35330d89d58bed2c59eda424e9ff4d45 147 SUPERFAMILY SSF55620 31 139 6.67E-20 T 28-03-2018 CU254_RS40990 35330d89d58bed2c59eda424e9ff4d45 147 Gene3D G3DSA:3.30.479.10 23 142 5.7E-20 T 28-03-2018 CU254_RS40990 35330d89d58bed2c59eda424e9ff4d45 147 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 31 140 1.6E-19 T 28-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 CU254_RS31920 4133edc61d6ae1a3fa07f153420ae237 142 Pfam PF01878 EVE domain 9 138 3.6E-10 T 28-03-2018 IPR002740 EVE domain CU254_RS31920 4133edc61d6ae1a3fa07f153420ae237 142 SUPERFAMILY SSF88697 7 140 2.48E-21 T 28-03-2018 IPR015947 PUA-like domain CU254_RS31920 4133edc61d6ae1a3fa07f153420ae237 142 Gene3D G3DSA:3.10.590.10 6 141 2.6E-9 T 28-03-2018 CU254_RS05260 770612372d128ba3a53b1fd7ef125dfb 192 Gene3D G3DSA:3.40.50.1000 1 187 5.2E-15 T 28-03-2018 IPR023214 HAD-like domain CU254_RS05260 770612372d128ba3a53b1fd7ef125dfb 192 SUPERFAMILY SSF56784 1 185 2.1E-21 T 28-03-2018 IPR023214 HAD-like domain CU254_RS34340 79b8a0e5efb49c2496473ef1d86f4b23 171 Gene3D G3DSA:2.30.110.10 1 169 4.1E-19 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS34340 79b8a0e5efb49c2496473ef1d86f4b23 171 SUPERFAMILY SSF50475 20 145 1.66E-17 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS34340 79b8a0e5efb49c2496473ef1d86f4b23 171 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 17 91 4.1E-9 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CU254_RS04280 d95eb59d642a5edd65d07c82259a1762 376 SUPERFAMILY SSF51679 8 360 1.96E-84 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS04280 d95eb59d642a5edd65d07c82259a1762 376 TIGRFAM TIGR04021 LLM_DMSO2_sfnG: dimethyl sulfone monooxygenase SfnG 10 361 2.6E-183 T 28-03-2018 IPR024014 Dimethyl sulphone monooxygenase SfnG CU254_RS04280 d95eb59d642a5edd65d07c82259a1762 376 Gene3D G3DSA:3.20.20.30 6 365 2.9E-72 T 28-03-2018 CU254_RS04280 d95eb59d642a5edd65d07c82259a1762 376 Pfam PF00296 Luciferase-like monooxygenase 11 333 5.5E-69 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS08470 97dc3dc039ba91ce6c6c3c397305c9b7 236 Pfam PF12710 haloacid dehalogenase-like hydrolase 10 190 4.5E-13 T 28-03-2018 CU254_RS08470 97dc3dc039ba91ce6c6c3c397305c9b7 236 Gene3D G3DSA:3.40.50.1000 79 233 1.1E-17 T 28-03-2018 IPR023214 HAD-like domain CU254_RS08470 97dc3dc039ba91ce6c6c3c397305c9b7 236 Gene3D G3DSA:1.10.150.240 29 78 7.7E-5 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CU254_RS08470 97dc3dc039ba91ce6c6c3c397305c9b7 236 SUPERFAMILY SSF56784 7 226 1.41E-29 T 28-03-2018 IPR023214 HAD-like domain CU254_RS03285 e47d11ccff1e3bc965e1bb1ba1d2dc27 275 SUPERFAMILY SSF55729 11 229 6.82E-21 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS03285 e47d11ccff1e3bc965e1bb1ba1d2dc27 275 Pfam PF13673 Acetyltransferase (GNAT) domain 65 124 5.2E-8 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS03285 e47d11ccff1e3bc965e1bb1ba1d2dc27 275 Gene3D G3DSA:3.40.630.30 3 133 9.8E-16 T 28-03-2018 CU254_RS15120 eae4e9420a2800596920a350293c07e0 594 Pfam PF01019 Gamma-glutamyltranspeptidase 28 587 1.1E-115 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CU254_RS15120 eae4e9420a2800596920a350293c07e0 594 SUPERFAMILY SSF56235 393 593 1.78E-126 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CU254_RS15120 eae4e9420a2800596920a350293c07e0 594 SUPERFAMILY SSF56235 3 355 1.78E-126 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CU254_RS15120 eae4e9420a2800596920a350293c07e0 594 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 452 467 3.4E-25 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CU254_RS15120 eae4e9420a2800596920a350293c07e0 594 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 398 416 3.4E-25 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CU254_RS15120 eae4e9420a2800596920a350293c07e0 594 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 105 123 3.4E-25 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CU254_RS15120 eae4e9420a2800596920a350293c07e0 594 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 123 142 3.4E-25 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CU254_RS15120 eae4e9420a2800596920a350293c07e0 594 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 35 60 3.4E-25 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CU254_RS05910 48248fa700f46274d56326179d8b25a3 146 Pfam PF00960 Neocarzinostatin family 36 145 6.1E-24 T 28-03-2018 IPR002186 Neocarzinostatin family GO:0003677|GO:0006952 CU254_RS05910 48248fa700f46274d56326179d8b25a3 146 PRINTS PR01885 Macromomycin family signature 33 52 6.2E-20 T 28-03-2018 IPR002186 Neocarzinostatin family GO:0003677|GO:0006952 CU254_RS05910 48248fa700f46274d56326179d8b25a3 146 PRINTS PR01885 Macromomycin family signature 56 71 6.2E-20 T 28-03-2018 IPR002186 Neocarzinostatin family GO:0003677|GO:0006952 CU254_RS05910 48248fa700f46274d56326179d8b25a3 146 PRINTS PR01885 Macromomycin family signature 87 104 6.2E-20 T 28-03-2018 IPR002186 Neocarzinostatin family GO:0003677|GO:0006952 CU254_RS05910 48248fa700f46274d56326179d8b25a3 146 PRINTS PR01885 Macromomycin family signature 111 127 6.2E-20 T 28-03-2018 IPR002186 Neocarzinostatin family GO:0003677|GO:0006952 CU254_RS05910 48248fa700f46274d56326179d8b25a3 146 SUPERFAMILY SSF49319 33 146 1.96E-27 T 28-03-2018 IPR027273 Neocarzinostatin-like CU254_RS05910 48248fa700f46274d56326179d8b25a3 146 Gene3D G3DSA:2.60.40.230 32 146 2.6E-13 T 28-03-2018 CU254_RS05910 48248fa700f46274d56326179d8b25a3 146 ProDom PD012709 ANTIBIOTIC DNA-BINDING DIRECT ANTIMICROBIAL SEQUENCING 3D-STRUCTURE PRECURSOR SIGNAL APOPROTEIN NEOCARZINOSTATIN 43 146 4.0E-16 T 28-03-2018 IPR002186 Neocarzinostatin family GO:0003677|GO:0006952 CU254_RS09025 9c141abfadb2ec454d91043a1c689353 447 Gene3D G3DSA:1.10.287.850 20 108 8.1E-13 T 28-03-2018 CU254_RS09025 9c141abfadb2ec454d91043a1c689353 447 SUPERFAMILY SSF140453 24 103 8.89E-8 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CU254_RS13145 a265dc2e9c844ef8470cd2bd18ee1073 508 Pfam PF07690 Major Facilitator Superfamily 29 419 5.1E-51 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS13145 a265dc2e9c844ef8470cd2bd18ee1073 508 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 26 481 6.4E-69 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CU254_RS13145 a265dc2e9c844ef8470cd2bd18ee1073 508 Gene3D G3DSA:1.20.1250.20 262 508 1.7E-27 T 28-03-2018 CU254_RS13145 a265dc2e9c844ef8470cd2bd18ee1073 508 SUPERFAMILY SSF103473 475 505 2.09E-67 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS13145 a265dc2e9c844ef8470cd2bd18ee1073 508 SUPERFAMILY SSF103473 17 209 2.09E-67 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS13145 a265dc2e9c844ef8470cd2bd18ee1073 508 SUPERFAMILY SSF103473 258 429 2.09E-67 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS13145 a265dc2e9c844ef8470cd2bd18ee1073 508 Gene3D G3DSA:1.20.1250.20 17 211 7.3E-35 T 28-03-2018 CU254_RS13145 a265dc2e9c844ef8470cd2bd18ee1073 508 PRINTS PR01036 Tetracycline resistance protein TetB signature 410 429 2.1E-5 T 28-03-2018 CU254_RS13145 a265dc2e9c844ef8470cd2bd18ee1073 508 PRINTS PR01036 Tetracycline resistance protein TetB signature 86 108 2.1E-5 T 28-03-2018 CU254_RS13145 a265dc2e9c844ef8470cd2bd18ee1073 508 PRINTS PR01036 Tetracycline resistance protein TetB signature 147 171 2.1E-5 T 28-03-2018 CU254_RS25995 d13ccf4864efad699e3bfad87a0620c1 447 Gene3D G3DSA:1.20.1250.20 7 222 2.4E-24 T 28-03-2018 CU254_RS25995 d13ccf4864efad699e3bfad87a0620c1 447 ProSitePatterns PS00216 Sugar transport proteins signature 1. 297 314 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CU254_RS25995 d13ccf4864efad699e3bfad87a0620c1 447 SUPERFAMILY SSF103473 6 424 2.35E-59 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS25995 d13ccf4864efad699e3bfad87a0620c1 447 Pfam PF07690 Major Facilitator Superfamily 46 372 2.0E-33 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS25995 d13ccf4864efad699e3bfad87a0620c1 447 Gene3D G3DSA:1.20.1250.20 223 430 4.6E-27 T 28-03-2018 CU254_RS18795 093f494d25d66304e26114c23103fc86 230 SMART SM00448 8 119 4.7E-42 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS18795 093f494d25d66304e26114c23103fc86 230 Pfam PF00072 Response regulator receiver domain 11 120 1.1E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS18795 093f494d25d66304e26114c23103fc86 230 SMART SM00862 151 227 3.1E-27 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS18795 093f494d25d66304e26114c23103fc86 230 Gene3D G3DSA:1.10.10.10 126 230 5.6E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS18795 093f494d25d66304e26114c23103fc86 230 Pfam PF00486 Transcriptional regulatory protein, C terminal 155 227 1.4E-26 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS18795 093f494d25d66304e26114c23103fc86 230 Gene3D G3DSA:3.40.50.2300 2 125 3.9E-40 T 28-03-2018 CU254_RS18795 093f494d25d66304e26114c23103fc86 230 SUPERFAMILY SSF52172 9 184 2.85E-43 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS18430 76887b11de0e5ac7b2bb7a840d0c43a2 305 Gene3D G3DSA:1.10.620.20 13 269 1.2E-30 T 28-03-2018 CU254_RS18430 76887b11de0e5ac7b2bb7a840d0c43a2 305 Pfam PF11583 P-aminobenzoate N-oxygenase AurF 16 289 9.9E-102 T 28-03-2018 IPR025859 P-aminobenzoate N-oxygenase AurF CU254_RS18430 76887b11de0e5ac7b2bb7a840d0c43a2 305 SUPERFAMILY SSF47240 59 236 5.35E-8 T 28-03-2018 IPR009078 Ferritin-like superfamily CU254_RS20755 2b5032ac89a650456be4ad7c2c14403e 295 Gene3D G3DSA:3.30.450.40 81 293 3.5E-23 T 28-03-2018 IPR029016 GAF domain-like CU254_RS20755 2b5032ac89a650456be4ad7c2c14403e 295 SUPERFAMILY SSF55781 66 220 1.11E-5 T 28-03-2018 IPR029016 GAF domain-like CU254_RS20755 2b5032ac89a650456be4ad7c2c14403e 295 SUPERFAMILY SSF46785 10 81 1.13E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS20755 2b5032ac89a650456be4ad7c2c14403e 295 SMART SM00346 7 98 4.1E-12 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS20755 2b5032ac89a650456be4ad7c2c14403e 295 Gene3D G3DSA:1.10.10.10 2 80 6.9E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS20755 2b5032ac89a650456be4ad7c2c14403e 295 Pfam PF09339 IclR helix-turn-helix domain 11 61 7.5E-10 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CU254_RS21640 356e8166f9dc7e5a5f6b1eb89dfc629f 180 SUPERFAMILY SSF54197 19 173 2.32E-40 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CU254_RS21640 356e8166f9dc7e5a5f6b1eb89dfc629f 180 Gene3D G3DSA:3.30.428.10 5 180 5.4E-39 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CU254_RS21640 356e8166f9dc7e5a5f6b1eb89dfc629f 180 Pfam PF01230 HIT domain 59 148 4.4E-12 T 28-03-2018 IPR001310 Histidine triad (HIT) protein CU254_RS03030 6c964686de91bda88f63f9e3fdc59ecd 440 Pfam PF00067 Cytochrome P450 184 377 3.4E-19 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS03030 6c964686de91bda88f63f9e3fdc59ecd 440 Gene3D G3DSA:1.10.630.10 46 392 6.5E-29 T 28-03-2018 CU254_RS03030 6c964686de91bda88f63f9e3fdc59ecd 440 SUPERFAMILY SSF48264 109 368 9.3E-34 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS40085 71b16040daebc8611fd26acd79a975a6 269 SMART SM00894 232 268 3.3E-19 T 28-03-2018 IPR008613 Excalibur calcium-binding domain CU254_RS40085 71b16040daebc8611fd26acd79a975a6 269 SUPERFAMILY SSF50199 66 180 2.75E-8 T 28-03-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold CU254_RS40085 71b16040daebc8611fd26acd79a975a6 269 Pfam PF05901 Excalibur calcium-binding domain 233 268 2.3E-14 T 28-03-2018 IPR008613 Excalibur calcium-binding domain CU254_RS40085 71b16040daebc8611fd26acd79a975a6 269 Gene3D G3DSA:2.40.50.90 57 183 2.7E-10 T 28-03-2018 IPR035437 Staphylococcal nuclease (SNase-like), OB-fold/extended TUDOR domain CU254_RS38870 9485bb865e4a58befd9ae7ecc727e44f 212 Pfam PF13419 Haloacid dehalogenase-like hydrolase 4 182 2.6E-22 T 28-03-2018 IPR023214 HAD-like domain CU254_RS38870 9485bb865e4a58befd9ae7ecc727e44f 212 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 3 181 7.6E-13 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CU254_RS38870 9485bb865e4a58befd9ae7ecc727e44f 212 Gene3D G3DSA:1.10.150.240 26 71 2.6E-20 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CU254_RS38870 9485bb865e4a58befd9ae7ecc727e44f 212 Gene3D G3DSA:3.40.50.1000 1 25 0.012 T 28-03-2018 IPR023214 HAD-like domain CU254_RS38870 9485bb865e4a58befd9ae7ecc727e44f 212 SUPERFAMILY SSF56784 1 211 3.72E-46 T 28-03-2018 IPR023214 HAD-like domain CU254_RS38870 9485bb865e4a58befd9ae7ecc727e44f 212 Gene3D G3DSA:3.40.50.1000 72 212 9.1E-24 T 28-03-2018 IPR023214 HAD-like domain CU254_RS17430 cd15205f25713dfb970f3b860b728553 369 PIRSF PIRSF000390 4 369 2.2E-98 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CU254_RS17430 cd15205f25713dfb970f3b860b728553 369 Gene3D G3DSA:3.90.1150.10 241 369 3.3E-40 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS17430 cd15205f25713dfb970f3b860b728553 369 SUPERFAMILY SSF53383 17 367 1.14E-102 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS17430 cd15205f25713dfb970f3b860b728553 369 Gene3D G3DSA:3.40.640.10 11 240 3.0E-44 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS17430 cd15205f25713dfb970f3b860b728553 369 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 16 364 8.7E-112 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CU254_RS30860 42a2bb5f20c854fb03696f1c3eed5384 334 Pfam PF06259 Alpha/beta hydrolase 142 249 6.4E-19 T 28-03-2018 IPR010427 Protein of unknown function DUF1023 CU254_RS30860 42a2bb5f20c854fb03696f1c3eed5384 334 Gene3D G3DSA:3.40.50.1820 87 326 1.2E-6 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS30860 42a2bb5f20c854fb03696f1c3eed5384 334 SUPERFAMILY SSF53474 159 252 2.38E-5 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS02415 0ea587dc0f6a9465df47d7868ae506c1 311 Pfam PF16751 Anti-sigma-D factor RsdA to sigma factor binding region 30 75 1.5E-12 T 28-03-2018 IPR031928 Anti-sigma-D factor RsdA, sigma factor binding region CU254_RS05025 e1563dcb59fd3bc5c574b0a1c013d1a9 371 SUPERFAMILY SSF54001 252 369 3.27E-32 T 28-03-2018 CU254_RS05025 e1563dcb59fd3bc5c574b0a1c013d1a9 371 Gene3D G3DSA:3.90.1720.10 252 371 2.0E-31 T 28-03-2018 CU254_RS05025 e1563dcb59fd3bc5c574b0a1c013d1a9 371 Pfam PF00877 NlpC/P60 family 271 365 9.9E-20 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CU254_RS10450 b4362ec70609772c123e6e3860911238 528 Gene3D G3DSA:3.50.50.60 3 518 5.9E-57 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS10450 b4362ec70609772c123e6e3860911238 528 SUPERFAMILY SSF51905 246 323 8.78E-38 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS10450 b4362ec70609772c123e6e3860911238 528 SUPERFAMILY SSF51905 463 518 8.78E-38 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS10450 b4362ec70609772c123e6e3860911238 528 SUPERFAMILY SSF51905 5 204 8.78E-38 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS10450 b4362ec70609772c123e6e3860911238 528 Pfam PF00890 FAD binding domain 7 489 1.5E-46 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CU254_RS10450 b4362ec70609772c123e6e3860911238 528 SUPERFAMILY SSF56425 310 447 8.02E-16 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CU254_RS18620 6c4215af14f4d9944240e3d1185e82da 200 SUPERFAMILY SSF109854 21 147 2.44E-36 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CU254_RS18620 6c4215af14f4d9944240e3d1185e82da 200 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 22 142 1.2E-22 T 28-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CU254_RS18620 6c4215af14f4d9944240e3d1185e82da 200 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 22 186 9.6E-27 T 28-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CU254_RS18620 6c4215af14f4d9944240e3d1185e82da 200 Gene3D G3DSA:1.20.120.450 15 148 1.8E-22 T 28-03-2018 CU254_RS17215 d53ca155264e294ccee4e06e4fe28150 187 SUPERFAMILY SSF55166 70 167 2.01E-14 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CU254_RS17215 d53ca155264e294ccee4e06e4fe28150 187 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 76 165 9.1E-7 T 28-03-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 CU254_RS17215 d53ca155264e294ccee4e06e4fe28150 187 Gene3D G3DSA:3.30.1380.10 37 175 3.8E-10 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CU254_RS13955 464124ec387c4a25fe638cc0d48c6785 322 SUPERFAMILY SSF103481 48 118 1.7E-5 T 28-03-2018 CU254_RS19890 550929fc5a75984b19cf81bcaccbf384 276 SUPERFAMILY SSF48008 141 272 5.23E-26 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS19890 550929fc5a75984b19cf81bcaccbf384 276 Pfam PF07729 FCD domain 144 267 6.6E-22 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS19890 550929fc5a75984b19cf81bcaccbf384 276 SMART SM00345 76 134 1.4E-12 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS19890 550929fc5a75984b19cf81bcaccbf384 276 Gene3D G3DSA:1.10.10.10 58 136 8.5E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS19890 550929fc5a75984b19cf81bcaccbf384 276 Pfam PF00392 Bacterial regulatory proteins, gntR family 73 134 1.4E-12 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS19890 550929fc5a75984b19cf81bcaccbf384 276 Gene3D G3DSA:1.20.120.530 137 275 2.5E-31 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS19890 550929fc5a75984b19cf81bcaccbf384 276 SUPERFAMILY SSF46785 67 138 3.98E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS19890 550929fc5a75984b19cf81bcaccbf384 276 SMART SM00895 144 268 1.6E-14 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS31110 ffe49ef9409a3f5bfaa6bf069006fb9b 171 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 23 34 2.8E-14 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS31110 ffe49ef9409a3f5bfaa6bf069006fb9b 171 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 7 23 2.8E-14 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS31110 ffe49ef9409a3f5bfaa6bf069006fb9b 171 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 34 53 2.8E-14 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS31110 ffe49ef9409a3f5bfaa6bf069006fb9b 171 SUPERFAMILY SSF54909 69 152 3.75E-16 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS31110 ffe49ef9409a3f5bfaa6bf069006fb9b 171 SMART SM00344 10 116 1.6E-34 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CU254_RS31110 ffe49ef9409a3f5bfaa6bf069006fb9b 171 Pfam PF01037 Lrp/AsnC ligand binding domain 75 146 2.2E-16 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CU254_RS31110 ffe49ef9409a3f5bfaa6bf069006fb9b 171 Gene3D G3DSA:3.30.70.920 60 144 4.1E-22 T 28-03-2018 CU254_RS31110 ffe49ef9409a3f5bfaa6bf069006fb9b 171 Gene3D G3DSA:1.10.10.10 9 59 2.6E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS31110 ffe49ef9409a3f5bfaa6bf069006fb9b 171 SUPERFAMILY SSF46785 7 66 1.65E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS31110 ffe49ef9409a3f5bfaa6bf069006fb9b 171 Pfam PF13412 Winged helix-turn-helix DNA-binding 8 54 4.3E-16 T 28-03-2018 CU254_RS12310 b0b66c2bb31a1f82d1800f54b472c02b 219 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 65 7.3E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS12310 b0b66c2bb31a1f82d1800f54b472c02b 219 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 35 49 7.3E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS12310 b0b66c2bb31a1f82d1800f54b472c02b 219 Gene3D G3DSA:1.10.10.10 1 71 9.1E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS12310 b0b66c2bb31a1f82d1800f54b472c02b 219 SUPERFAMILY SSF46785 12 79 1.3E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS12310 b0b66c2bb31a1f82d1800f54b472c02b 219 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 75 2.6E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS12310 b0b66c2bb31a1f82d1800f54b472c02b 219 SMART SM00345 17 75 2.2E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CU254_RS12310 b0b66c2bb31a1f82d1800f54b472c02b 219 Pfam PF07729 FCD domain 86 207 7.0E-27 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS12310 b0b66c2bb31a1f82d1800f54b472c02b 219 Gene3D G3DSA:1.20.120.530 72 218 3.2E-37 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS12310 b0b66c2bb31a1f82d1800f54b472c02b 219 SMART SM00895 85 208 1.8E-19 T 28-03-2018 IPR011711 GntR, C-terminal CU254_RS12310 b0b66c2bb31a1f82d1800f54b472c02b 219 SUPERFAMILY SSF48008 82 213 9.42E-26 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CU254_RS26540 a4001ff87ade0a78d1eced3061456b5f 280 Gene3D G3DSA:3.60.110.10 1 280 2.0E-75 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CU254_RS26540 a4001ff87ade0a78d1eced3061456b5f 280 SUPERFAMILY SSF56317 3 277 1.23E-77 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CU254_RS26540 a4001ff87ade0a78d1eced3061456b5f 280 Pfam PF00795 Carbon-nitrogen hydrolase 6 260 8.4E-62 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CU254_RS30520 b505396f8c5d41413e313083a7ba5673 319 Gene3D G3DSA:1.10.3720.10 1 302 7.0E-40 T 28-03-2018 CU254_RS30520 b505396f8c5d41413e313083a7ba5673 319 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 313 5.5E-38 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS30520 b505396f8c5d41413e313083a7ba5673 319 SUPERFAMILY SSF161098 91 301 3.01E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS01710 f4a54fec3820db99176e69e638fc3231 300 SUPERFAMILY SSF51679 5 289 1.96E-57 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS01710 f4a54fec3820db99176e69e638fc3231 300 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 25 276 1.2E-60 T 28-03-2018 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted CU254_RS01710 f4a54fec3820db99176e69e638fc3231 300 Gene3D G3DSA:3.20.20.30 1 297 1.6E-62 T 28-03-2018 CU254_RS01710 f4a54fec3820db99176e69e638fc3231 300 Pfam PF00296 Luciferase-like monooxygenase 13 259 7.4E-46 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS37395 a4537ec03cbf10036184fad6b27057a9 277 Gene3D G3DSA:3.40.50.1820 2 277 3.0E-45 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS37395 a4537ec03cbf10036184fad6b27057a9 277 Pfam PF00561 alpha/beta hydrolase fold 26 261 1.3E-22 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS37395 a4537ec03cbf10036184fad6b27057a9 277 PRINTS PR00111 Alpha/beta hydrolase fold signature 97 110 7.0E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS37395 a4537ec03cbf10036184fad6b27057a9 277 PRINTS PR00111 Alpha/beta hydrolase fold signature 111 124 7.0E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS37395 a4537ec03cbf10036184fad6b27057a9 277 PRINTS PR00111 Alpha/beta hydrolase fold signature 51 66 7.0E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS37395 a4537ec03cbf10036184fad6b27057a9 277 SUPERFAMILY SSF53474 4 275 3.98E-61 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS37395 a4537ec03cbf10036184fad6b27057a9 277 PRINTS PR00412 Epoxide hydrolase signature 51 66 2.6E-21 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS37395 a4537ec03cbf10036184fad6b27057a9 277 PRINTS PR00412 Epoxide hydrolase signature 31 49 2.6E-21 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS37395 a4537ec03cbf10036184fad6b27057a9 277 PRINTS PR00412 Epoxide hydrolase signature 251 273 2.6E-21 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS37395 a4537ec03cbf10036184fad6b27057a9 277 PRINTS PR00412 Epoxide hydrolase signature 111 124 2.6E-21 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS37395 a4537ec03cbf10036184fad6b27057a9 277 PRINTS PR00412 Epoxide hydrolase signature 97 110 2.6E-21 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS37395 a4537ec03cbf10036184fad6b27057a9 277 PRINTS PR00412 Epoxide hydrolase signature 217 233 2.6E-21 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS07880 731181e998d85e0a08982797d05066d4 280 Gene3D G3DSA:3.40.50.150 8 268 8.5E-39 T 28-03-2018 CU254_RS07880 731181e998d85e0a08982797d05066d4 280 Pfam PF04072 Leucine carboxyl methyltransferase 15 184 2.2E-41 T 28-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CU254_RS07880 731181e998d85e0a08982797d05066d4 280 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 13 260 2.7E-42 T 28-03-2018 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 CU254_RS07880 731181e998d85e0a08982797d05066d4 280 SUPERFAMILY SSF53335 12 272 3.2E-57 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS11420 c9f935848fb895382d0bb91f027651ef 175 Hamap MF_00109 Shikimate kinase [aroK]. 3 168 25.372 T 28-03-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CU254_RS11420 c9f935848fb895382d0bb91f027651ef 175 PRINTS PR01100 Shikimate kinase family signature 6 21 3.2E-13 T 28-03-2018 CU254_RS11420 c9f935848fb895382d0bb91f027651ef 175 PRINTS PR01100 Shikimate kinase family signature 58 66 3.2E-13 T 28-03-2018 CU254_RS11420 c9f935848fb895382d0bb91f027651ef 175 PRINTS PR01100 Shikimate kinase family signature 76 85 3.2E-13 T 28-03-2018 CU254_RS11420 c9f935848fb895382d0bb91f027651ef 175 PRINTS PR01100 Shikimate kinase family signature 30 43 3.2E-13 T 28-03-2018 CU254_RS11420 c9f935848fb895382d0bb91f027651ef 175 PRINTS PR01100 Shikimate kinase family signature 96 113 3.2E-13 T 28-03-2018 CU254_RS11420 c9f935848fb895382d0bb91f027651ef 175 SUPERFAMILY SSF52540 4 166 5.68E-24 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS11420 c9f935848fb895382d0bb91f027651ef 175 Gene3D G3DSA:3.40.50.300 3 174 6.4E-30 T 28-03-2018 CU254_RS11420 c9f935848fb895382d0bb91f027651ef 175 Pfam PF01202 Shikimate kinase 12 167 1.0E-39 T 28-03-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CU254_RS06510 d4dd0cbae20e51337c39a1356924dec5 318 SUPERFAMILY SSF53335 34 181 5.43E-37 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS06510 d4dd0cbae20e51337c39a1356924dec5 318 SUPERFAMILY SSF53335 227 253 5.43E-37 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS06510 d4dd0cbae20e51337c39a1356924dec5 318 Pfam PF08241 Methyltransferase domain 73 169 2.2E-22 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CU254_RS06510 d4dd0cbae20e51337c39a1356924dec5 318 Gene3D G3DSA:3.40.50.150 18 285 6.9E-32 T 28-03-2018 CU254_RS01720 3b25a87deff698bccdb41a0ca0879cc4 146 Hamap MF_00422 Protein translocase subunit SecE [secE]. 88 143 12.55 T 28-03-2018 IPR022943 Preprotein translocase subunit SecE Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CU254_RS01720 3b25a87deff698bccdb41a0ca0879cc4 146 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 92 143 8.5E-20 T 28-03-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CU254_RS01720 3b25a87deff698bccdb41a0ca0879cc4 146 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 90 146 9.6E-21 T 28-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 CU254_RS01720 3b25a87deff698bccdb41a0ca0879cc4 146 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 93 121 - T 28-03-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CU254_RS01720 3b25a87deff698bccdb41a0ca0879cc4 146 Gene3D G3DSA:1.20.5.1030 90 141 2.3E-20 T 28-03-2018 CU254_RS22100 6c3add80d689d1ae52c0ca2849d05864 314 Gene3D G3DSA:3.40.50.720 8 311 1.4E-72 T 28-03-2018 CU254_RS22100 6c3add80d689d1ae52c0ca2849d05864 314 SUPERFAMILY SSF51735 8 306 2.94E-86 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS22100 6c3add80d689d1ae52c0ca2849d05864 314 Pfam PF01370 NAD dependent epimerase/dehydratase family 12 234 8.9E-54 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CU254_RS18980 b5d4e52427683008231c8c7c1bb1eb42 158 Gene3D G3DSA:2.60.120.10 1 155 2.2E-22 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS18980 b5d4e52427683008231c8c7c1bb1eb42 158 Pfam PF07883 Cupin domain 37 106 5.6E-16 T 28-03-2018 IPR013096 Cupin 2, conserved barrel CU254_RS18980 b5d4e52427683008231c8c7c1bb1eb42 158 SUPERFAMILY SSF51182 14 138 2.29E-23 T 28-03-2018 IPR011051 RmlC-like cupin domain CU254_RS06240 8439391d905018319e42a08cca5fb0c4 344 Gene3D G3DSA:1.10.10.10 4 79 2.7E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS06240 8439391d905018319e42a08cca5fb0c4 344 SUPERFAMILY SSF54909 68 148 2.55E-8 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS06240 8439391d905018319e42a08cca5fb0c4 344 Gene3D G3DSA:3.30.70.920 232 320 1.6E-6 T 28-03-2018 CU254_RS06240 8439391d905018319e42a08cca5fb0c4 344 Gene3D G3DSA:3.30.70.920 80 138 1.1E-9 T 28-03-2018 CU254_RS06240 8439391d905018319e42a08cca5fb0c4 344 Gene3D G3DSA:1.10.10.10 185 231 3.6E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS06240 8439391d905018319e42a08cca5fb0c4 344 Pfam PF13404 AsnC-type helix-turn-helix domain 9 46 9.8E-8 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CU254_RS06240 8439391d905018319e42a08cca5fb0c4 344 Pfam PF01037 Lrp/AsnC ligand binding domain 70 138 3.3E-6 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CU254_RS14500 4d72ac884b5f3c01ffe51a72ecd82813 161 Pfam PF12802 MarR family 41 94 4.3E-11 T 28-03-2018 CU254_RS14500 4d72ac884b5f3c01ffe51a72ecd82813 161 SMART SM00347 35 133 4.2E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS14500 4d72ac884b5f3c01ffe51a72ecd82813 161 SUPERFAMILY SSF46785 10 146 5.47E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS14500 4d72ac884b5f3c01ffe51a72ecd82813 161 Gene3D G3DSA:1.10.10.10 4 155 2.4E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS14500 4d72ac884b5f3c01ffe51a72ecd82813 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 76 91 1.1E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS14500 4d72ac884b5f3c01ffe51a72ecd82813 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 123 143 1.1E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS14500 4d72ac884b5f3c01ffe51a72ecd82813 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 59 75 1.1E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS40785 8ea7a6827c959a147e57b909953021b8 117 SUPERFAMILY SSF52091 20 111 2.16E-18 T 28-03-2018 IPR002645 STAS domain CU254_RS40785 8ea7a6827c959a147e57b909953021b8 117 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 16 113 8.3E-18 T 28-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 CU254_RS40785 8ea7a6827c959a147e57b909953021b8 117 Gene3D G3DSA:3.30.750.24 18 114 1.9E-14 T 28-03-2018 IPR002645 STAS domain CU254_RS40785 8ea7a6827c959a147e57b909953021b8 117 Pfam PF13466 STAS domain 26 105 3.4E-16 T 28-03-2018 IPR002645 STAS domain CU254_RS11155 2b36c751f4901574f94c4e55f3230541 218 SUPERFAMILY SSF109854 3 152 9.16E-11 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CU254_RS11155 2b36c751f4901574f94c4e55f3230541 218 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 6 149 1.5E-15 T 28-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CU254_RS11155 2b36c751f4901574f94c4e55f3230541 218 Gene3D G3DSA:1.20.120.450 1 155 3.6E-20 T 28-03-2018 CU254_RS13545 7de84680fb79cb3d732989bb009e7481 460 Pfam PF07690 Major Facilitator Superfamily 77 415 7.4E-35 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS13545 7de84680fb79cb3d732989bb009e7481 460 Gene3D G3DSA:1.20.1250.20 47 244 1.4E-20 T 28-03-2018 CU254_RS13545 7de84680fb79cb3d732989bb009e7481 460 SUPERFAMILY SSF103473 51 450 3.79E-44 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS13545 7de84680fb79cb3d732989bb009e7481 460 Gene3D G3DSA:1.20.1250.20 269 459 3.6E-13 T 28-03-2018 CU254_RS12880 bad4aec1e3dc9586b2f95b5e8cee08bd 404 Gene3D G3DSA:3.40.50.1970 19 208 1.4E-32 T 28-03-2018 CU254_RS12880 bad4aec1e3dc9586b2f95b5e8cee08bd 404 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 284 304 - T 28-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 CU254_RS12880 bad4aec1e3dc9586b2f95b5e8cee08bd 404 SUPERFAMILY SSF56796 22 403 1.28E-87 T 28-03-2018 CU254_RS12880 bad4aec1e3dc9586b2f95b5e8cee08bd 404 Pfam PF00465 Iron-containing alcohol dehydrogenase 23 393 2.0E-86 T 28-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 CU254_RS12880 bad4aec1e3dc9586b2f95b5e8cee08bd 404 Gene3D G3DSA:1.20.1090.10 209 404 1.2E-51 T 28-03-2018 CU254_RS26800 555763bf57645cfa9b8a8812a368ba66 244 Gene3D G3DSA:3.40.50.720 1 46 1.1E-11 T 28-03-2018 CU254_RS26800 555763bf57645cfa9b8a8812a368ba66 244 Gene3D G3DSA:3.40.50.720 47 244 4.6E-67 T 28-03-2018 CU254_RS26800 555763bf57645cfa9b8a8812a368ba66 244 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 242 2.9E-73 T 28-03-2018 CU254_RS26800 555763bf57645cfa9b8a8812a368ba66 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 1.8E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS26800 555763bf57645cfa9b8a8812a368ba66 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 1.8E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS26800 555763bf57645cfa9b8a8812a368ba66 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 1.8E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS26800 555763bf57645cfa9b8a8812a368ba66 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 225 1.8E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS26800 555763bf57645cfa9b8a8812a368ba66 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 1.8E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS26800 555763bf57645cfa9b8a8812a368ba66 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 1.8E-42 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS26800 555763bf57645cfa9b8a8812a368ba66 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 2.3E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS26800 555763bf57645cfa9b8a8812a368ba66 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 2.3E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS26800 555763bf57645cfa9b8a8812a368ba66 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 128 136 2.3E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS26800 555763bf57645cfa9b8a8812a368ba66 244 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 135 163 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS26800 555763bf57645cfa9b8a8812a368ba66 244 SUPERFAMILY SSF51735 3 243 1.26E-85 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS08615 f1cb111508bb54d0882e7a38f2c04753 155 Pfam PF00578 AhpC/TSA family 5 130 3.0E-40 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CU254_RS08615 f1cb111508bb54d0882e7a38f2c04753 155 Gene3D G3DSA:3.40.30.10 1 152 8.1E-43 T 28-03-2018 CU254_RS08615 f1cb111508bb54d0882e7a38f2c04753 155 PIRSF PIRSF000239 1 152 1.5E-26 T 28-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CU254_RS08615 f1cb111508bb54d0882e7a38f2c04753 155 SUPERFAMILY SSF52833 1 152 9.53E-50 T 28-03-2018 IPR012336 Thioredoxin-like fold CU254_RS10495 56810f5693eda687ee88c69f66789bb1 349 Pfam PF12706 Beta-lactamase superfamily domain 101 296 4.0E-50 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS10495 56810f5693eda687ee88c69f66789bb1 349 Gene3D G3DSA:3.60.15.10 61 340 2.6E-53 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS10495 56810f5693eda687ee88c69f66789bb1 349 SUPERFAMILY SSF56281 81 312 7.34E-34 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS37850 14f33561e669e01e4b1531e819157e26 340 Pfam PF01212 Beta-eliminating lyase 9 290 2.0E-73 T 28-03-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 CU254_RS37850 14f33561e669e01e4b1531e819157e26 340 Gene3D G3DSA:3.40.640.10 3 255 1.0E-45 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS37850 14f33561e669e01e4b1531e819157e26 340 SUPERFAMILY SSF53383 8 337 3.9E-93 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS37850 14f33561e669e01e4b1531e819157e26 340 PIRSF PIRSF017617 1 340 6.8E-105 T 28-03-2018 IPR023603 Threonine aldolase CU254_RS37850 14f33561e669e01e4b1531e819157e26 340 Gene3D G3DSA:3.90.1150.10 256 339 2.9E-15 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS00425 8ae65c35a06ab9a2ec2e4c5f4774c35e 371 Gene3D G3DSA:3.40.390.10 95 368 9.5E-4 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CU254_RS06315 e83294fde8482e1eae3e9454ffc00961 368 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 164 313 8.2E-14 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CU254_RS06315 e83294fde8482e1eae3e9454ffc00961 368 Gene3D G3DSA:3.30.70.1230 156 316 3.0E-29 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CU254_RS06315 e83294fde8482e1eae3e9454ffc00961 368 SUPERFAMILY SSF55073 160 314 2.51E-33 T 28-03-2018 IPR029787 Nucleotide cyclase CU254_RS06315 e83294fde8482e1eae3e9454ffc00961 368 Pfam PF16701 Adenylate cyclase regulatory domain 15 136 1.9E-11 T 28-03-2018 IPR032026 Adenylate cyclase regulatory domain CU254_RS20840 6be91be75df5a3cd10b23225f14a3ad8 253 SMART SM00382 34 219 7.5E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS20840 6be91be75df5a3cd10b23225f14a3ad8 253 Pfam PF00005 ABC transporter 25 171 1.5E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS20840 6be91be75df5a3cd10b23225f14a3ad8 253 Gene3D G3DSA:3.40.50.300 2 247 1.7E-66 T 28-03-2018 CU254_RS20840 6be91be75df5a3cd10b23225f14a3ad8 253 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS20840 6be91be75df5a3cd10b23225f14a3ad8 253 SUPERFAMILY SSF52540 6 224 5.45E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS27225 6b724408e202950d5fa3a9c456724aa5 250 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 78 150 4.6E-16 T 28-03-2018 IPR022385 Rhs repeat-associated core GO:0097264 CU254_RS02935 d2c667df8e020f40a2a3ac17189b3ece 253 Pfam PF08241 Methyltransferase domain 37 123 6.8E-12 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CU254_RS02935 d2c667df8e020f40a2a3ac17189b3ece 253 Gene3D G3DSA:3.40.50.150 17 251 5.6E-28 T 28-03-2018 CU254_RS02935 d2c667df8e020f40a2a3ac17189b3ece 253 SUPERFAMILY SSF53335 5 209 4.18E-25 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS27510 b3f273fd16b9e67c89650632bbabb1fa 160 Pfam PF17174 Domain of unknown function (DUF5130) 17 151 7.9E-42 T 28-03-2018 IPR033437 Protein of unknown function DUF5130 CU254_RS16310 2dfa35de3e54a6227f2d52ce99aebe85 298 SUPERFAMILY SSF103481 198 296 1.83E-16 T 28-03-2018 CU254_RS16310 2dfa35de3e54a6227f2d52ce99aebe85 298 SUPERFAMILY SSF103481 52 154 1.96E-11 T 28-03-2018 CU254_RS16310 2dfa35de3e54a6227f2d52ce99aebe85 298 Pfam PF00892 EamA-like transporter family 162 294 7.3E-27 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CU254_RS16310 2dfa35de3e54a6227f2d52ce99aebe85 298 Pfam PF00892 EamA-like transporter family 23 152 2.6E-16 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CU254_RS19785 09f3abebd0e0ef7498cb68c75ba71661 992 Pfam PF14896 EmbC C-terminal domain 736 981 5.4E-32 T 28-03-2018 IPR032731 Arabinosyltransferase, C-terminal CU254_RS19785 09f3abebd0e0ef7498cb68c75ba71661 992 Pfam PF04602 Mycobacterial cell wall arabinan synthesis protein 18 622 2.1E-164 T 28-03-2018 IPR007680 Arabinofuranosyltransferase, N-terminal GO:0052636|GO:0071766 CU254_RS19785 09f3abebd0e0ef7498cb68c75ba71661 992 Gene3D G3DSA:2.60.120.610 36 180 2.9E-22 T 28-03-2018 IPR027451 Arabinofuranosyltransferase, domain 1 CU254_RS09735 17df846c8d011e7a34d7f78312191f01 168 SUPERFAMILY SSF46785 14 88 1.76E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS09735 17df846c8d011e7a34d7f78312191f01 168 Gene3D G3DSA:1.10.10.10 1 150 4.3E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS09735 17df846c8d011e7a34d7f78312191f01 168 Pfam PF12840 Helix-turn-helix domain 13 69 4.0E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS17750 1a16b698e288888a1f77d637dd5f0a43 294 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 41 239 1.5E-35 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CU254_RS17750 1a16b698e288888a1f77d637dd5f0a43 294 Gene3D G3DSA:2.10.109.10 51 254 2.6E-43 T 28-03-2018 CU254_RS17750 1a16b698e288888a1f77d637dd5f0a43 294 Pfam PF10502 Signal peptidase, peptidase S26 133 237 2.4E-7 T 28-03-2018 IPR019533 Peptidase S26 CU254_RS17750 1a16b698e288888a1f77d637dd5f0a43 294 SUPERFAMILY SSF51306 138 246 4.45E-43 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CU254_RS17750 1a16b698e288888a1f77d637dd5f0a43 294 SUPERFAMILY SSF51306 54 106 4.45E-43 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CU254_RS17750 1a16b698e288888a1f77d637dd5f0a43 294 ProSitePatterns PS00761 Signal peptidases I signature 3. 199 212 - T 28-03-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 CU254_RS17750 1a16b698e288888a1f77d637dd5f0a43 294 Pfam PF00717 Peptidase S24-like 62 108 3.7E-5 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CU254_RS17750 1a16b698e288888a1f77d637dd5f0a43 294 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 55 71 3.1E-19 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CU254_RS17750 1a16b698e288888a1f77d637dd5f0a43 294 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 194 213 3.1E-19 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CU254_RS17750 1a16b698e288888a1f77d637dd5f0a43 294 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 143 155 3.1E-19 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CU254_RS13890 4130d1fe4d37109bc24843a67ca71d1d 441 Gene3D G3DSA:1.20.1250.20 209 402 3.2E-16 T 28-03-2018 CU254_RS13890 4130d1fe4d37109bc24843a67ca71d1d 441 Gene3D G3DSA:1.20.1250.20 7 205 2.2E-30 T 28-03-2018 CU254_RS13890 4130d1fe4d37109bc24843a67ca71d1d 441 Pfam PF07690 Major Facilitator Superfamily 34 247 1.3E-28 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS13890 4130d1fe4d37109bc24843a67ca71d1d 441 SUPERFAMILY SSF103473 19 383 1.19E-51 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS30840 628b93b14455c519ad4eeaae12bbdd3e 199 SUPERFAMILY SSF48498 85 195 1.45E-5 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS30840 628b93b14455c519ad4eeaae12bbdd3e 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 2.8E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS30840 628b93b14455c519ad4eeaae12bbdd3e 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 2.8E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS30840 628b93b14455c519ad4eeaae12bbdd3e 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 64 8.8E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS30840 628b93b14455c519ad4eeaae12bbdd3e 199 Gene3D G3DSA:1.10.357.10 69 198 8.2E-17 T 28-03-2018 CU254_RS30840 628b93b14455c519ad4eeaae12bbdd3e 199 SUPERFAMILY SSF46689 5 88 3.29E-19 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS30840 628b93b14455c519ad4eeaae12bbdd3e 199 Gene3D G3DSA:1.10.10.60 1 39 6.4E-14 T 28-03-2018 CU254_RS30840 628b93b14455c519ad4eeaae12bbdd3e 199 Gene3D G3DSA:1.10.260.40 40 68 4.8E-13 T 28-03-2018 CU254_RS30840 628b93b14455c519ad4eeaae12bbdd3e 199 ProSitePatterns PS01081 TetR-type HTH domain signature. 30 61 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CU254_RS14350 ce1d6f06c1b13afa565294e0516a934a 229 Pfam PF02633 Creatinine amidohydrolase 5 218 4.1E-57 T 28-03-2018 IPR003785 Creatininase/formamide hydrolase KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 CU254_RS14350 ce1d6f06c1b13afa565294e0516a934a 229 Gene3D G3DSA:3.40.50.10310 1 227 2.3E-65 T 28-03-2018 IPR024087 Creatininase-like domain KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 CU254_RS14350 ce1d6f06c1b13afa565294e0516a934a 229 SUPERFAMILY SSF102215 1 223 1.03E-57 T 28-03-2018 IPR024087 Creatininase-like domain KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|KEGG: 00740+3.5.1.102|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-6167 CU254_RS14350 ce1d6f06c1b13afa565294e0516a934a 229 TIGRFAM TIGR03964 mycofact_creat: mycofactocin system creatininase family protein 3 225 1.1E-88 T 28-03-2018 IPR023871 Mycofactocin system creatininase family protein CU254_RS15770 6eb17ad9534f597440adebc47c7a263a 186 Pfam PF01814 Hemerythrin HHE cation binding domain 9 126 3.8E-16 T 28-03-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 CU254_RS15770 6eb17ad9534f597440adebc47c7a263a 186 Gene3D G3DSA:1.20.120.520 5 169 3.8E-26 T 28-03-2018 CU254_RS17850 acddc51b1cb023d5ce25b2f55a0a81ac 183 SUPERFAMILY SSF103025 63 178 1.73E-11 T 28-03-2018 CU254_RS17850 acddc51b1cb023d5ce25b2f55a0a81ac 183 Pfam PF04268 Sarcosine oxidase, gamma subunit family 45 176 2.8E-27 T 28-03-2018 IPR007375 Sarcosine oxidase, gamma subunit KEGG: 00260+1.5.3.1|MetaCyc: PWY-3661|MetaCyc: PWY-4722 CU254_RS17850 acddc51b1cb023d5ce25b2f55a0a81ac 183 Gene3D G3DSA:3.30.70.1520 30 100 8.2E-14 T 28-03-2018 CU254_RS36270 12e0538bf607b17761fe8818d4d9fd32 257 SUPERFAMILY SSF53067 2 119 1.27E-27 T 28-03-2018 CU254_RS36270 12e0538bf607b17761fe8818d4d9fd32 257 Gene3D G3DSA:3.30.420.40 87 257 1.2E-54 T 28-03-2018 CU254_RS36270 12e0538bf607b17761fe8818d4d9fd32 257 SUPERFAMILY SSF53067 122 255 2.27E-33 T 28-03-2018 CU254_RS36270 12e0538bf607b17761fe8818d4d9fd32 257 Pfam PF03309 Type III pantothenate kinase 2 204 9.3E-62 T 28-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CU254_RS36270 12e0538bf607b17761fe8818d4d9fd32 257 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 2 252 2.0E-71 T 28-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CU254_RS36270 12e0538bf607b17761fe8818d4d9fd32 257 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 256 32.876 T 28-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CU254_RS11575 28fd7922b7b26899c4d01379efb043c2 474 SUPERFAMILY SSF53335 176 473 3.63E-49 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS11575 28fd7922b7b26899c4d01379efb043c2 474 SUPERFAMILY SSF48013 32 186 5.89E-32 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CU254_RS11575 28fd7922b7b26899c4d01379efb043c2 474 Gene3D G3DSA:3.40.50.150 268 474 4.0E-43 T 28-03-2018 CU254_RS11575 28fd7922b7b26899c4d01379efb043c2 474 Pfam PF01189 16S rRNA methyltransferase RsmB/F 288 472 2.3E-46 T 28-03-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CU254_RS11575 28fd7922b7b26899c4d01379efb043c2 474 Pfam PF01029 NusB family 32 154 8.5E-27 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CU254_RS11575 28fd7922b7b26899c4d01379efb043c2 474 Gene3D G3DSA:1.10.940.10 30 171 2.8E-28 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CU254_RS11575 28fd7922b7b26899c4d01379efb043c2 474 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 292 302 3.4E-20 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CU254_RS11575 28fd7922b7b26899c4d01379efb043c2 474 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 405 421 3.4E-20 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CU254_RS11575 28fd7922b7b26899c4d01379efb043c2 474 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 259 273 3.4E-20 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CU254_RS11575 28fd7922b7b26899c4d01379efb043c2 474 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 456 473 3.4E-20 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CU254_RS11575 28fd7922b7b26899c4d01379efb043c2 474 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 355 367 3.4E-20 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CU254_RS02155 eafee6113ae90721dbdef69fb37ecdab 551 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 121 131 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CU254_RS02155 eafee6113ae90721dbdef69fb37ecdab 551 Gene3D G3DSA:3.40.50.200 92 495 1.5E-72 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS02155 eafee6113ae90721dbdef69fb37ecdab 551 PRINTS PR00723 Subtilisin serine protease family (S8) signature 116 135 3.3E-12 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CU254_RS02155 eafee6113ae90721dbdef69fb37ecdab 551 PRINTS PR00723 Subtilisin serine protease family (S8) signature 158 171 3.3E-12 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CU254_RS02155 eafee6113ae90721dbdef69fb37ecdab 551 PRINTS PR00723 Subtilisin serine protease family (S8) signature 422 438 3.3E-12 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CU254_RS02155 eafee6113ae90721dbdef69fb37ecdab 551 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 162 172 - T 28-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site CU254_RS02155 eafee6113ae90721dbdef69fb37ecdab 551 Pfam PF00082 Subtilase family 267 474 8.0E-24 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS02155 eafee6113ae90721dbdef69fb37ecdab 551 Pfam PF00082 Subtilase family 119 201 1.7E-10 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS02155 eafee6113ae90721dbdef69fb37ecdab 551 SUPERFAMILY SSF52743 91 197 1.04E-61 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS02155 eafee6113ae90721dbdef69fb37ecdab 551 SUPERFAMILY SSF52743 268 484 1.04E-61 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CU254_RS02155 eafee6113ae90721dbdef69fb37ecdab 551 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 423 433 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CU254_RS37735 197cf04bafcad44e23ddc91afec24a3d 176 Pfam PF03358 NADPH-dependent FMN reductase 5 138 1.4E-23 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CU254_RS37735 197cf04bafcad44e23ddc91afec24a3d 176 Gene3D G3DSA:3.40.50.360 4 176 1.9E-27 T 28-03-2018 IPR029039 Flavoprotein-like domain CU254_RS37735 197cf04bafcad44e23ddc91afec24a3d 176 SUPERFAMILY SSF52218 5 171 5.87E-31 T 28-03-2018 IPR029039 Flavoprotein-like domain CU254_RS05065 0378d39b9bca59c54ca3e565344ef789 221 SUPERFAMILY SSF55729 154 210 1.15E-9 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS05065 0378d39b9bca59c54ca3e565344ef789 221 Pfam PF08445 FR47-like protein 159 210 4.2E-6 T 28-03-2018 IPR013653 FR47-like GO:0016747 CU254_RS05065 0378d39b9bca59c54ca3e565344ef789 221 Gene3D G3DSA:3.40.630.30 6 215 7.1E-10 T 28-03-2018 CU254_RS15115 c030c4eed67d619fe2634f44652facda 297 SUPERFAMILY SSF53850 87 293 2.9E-27 T 28-03-2018 CU254_RS15115 c030c4eed67d619fe2634f44652facda 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.4E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS15115 c030c4eed67d619fe2634f44652facda 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.4E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS15115 c030c4eed67d619fe2634f44652facda 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.4E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS15115 c030c4eed67d619fe2634f44652facda 297 Gene3D G3DSA:1.10.10.10 1 83 2.7E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS15115 c030c4eed67d619fe2634f44652facda 297 Gene3D G3DSA:3.40.190.10 84 173 3.4E-13 T 28-03-2018 CU254_RS15115 c030c4eed67d619fe2634f44652facda 297 Pfam PF03466 LysR substrate binding domain 87 288 1.7E-26 T 28-03-2018 IPR005119 LysR, substrate-binding CU254_RS15115 c030c4eed67d619fe2634f44652facda 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 3.0E-22 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS15115 c030c4eed67d619fe2634f44652facda 297 SUPERFAMILY SSF46785 1 83 9.83E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS15115 c030c4eed67d619fe2634f44652facda 297 Gene3D G3DSA:3.40.190.10 174 266 3.6E-10 T 28-03-2018 CU254_RS17810 905a8ee52fd9a63eac07f50966236a09 144 Gene3D G3DSA:2.40.440.10 33 144 8.2E-22 T 28-03-2018 CU254_RS17810 905a8ee52fd9a63eac07f50966236a09 144 Pfam PF03734 L,D-transpeptidase catalytic domain 43 142 5.3E-17 T 28-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CU254_RS17810 905a8ee52fd9a63eac07f50966236a09 144 SUPERFAMILY SSF141523 38 142 6.02E-24 T 28-03-2018 CU254_RS17235 a021185087630c61167b0efdd884f72e 233 Pfam PF00106 short chain dehydrogenase 7 184 2.6E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS17235 a021185087630c61167b0efdd884f72e 233 SUPERFAMILY SSF51735 4 224 1.97E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS17235 a021185087630c61167b0efdd884f72e 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 141 160 2.3E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS17235 a021185087630c61167b0efdd884f72e 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 70 81 2.3E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS17235 a021185087630c61167b0efdd884f72e 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 2.3E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS17235 a021185087630c61167b0efdd884f72e 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 117 133 2.3E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS17235 a021185087630c61167b0efdd884f72e 233 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 179 2.3E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS17235 a021185087630c61167b0efdd884f72e 233 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 177 0.01 T 28-03-2018 CU254_RS17235 a021185087630c61167b0efdd884f72e 233 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 70 81 3.4E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS17235 a021185087630c61167b0efdd884f72e 233 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 160 3.4E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS17235 a021185087630c61167b0efdd884f72e 233 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 123 131 3.4E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS17235 a021185087630c61167b0efdd884f72e 233 Gene3D G3DSA:3.40.50.720 4 222 5.9E-44 T 28-03-2018 CU254_RS41020 5a4b58efbc999aaf428b922560df1eb0 240 Gene3D G3DSA:3.20.20.70 6 225 1.2E-50 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS41020 5a4b58efbc999aaf428b922560df1eb0 240 Pfam PF00834 Ribulose-phosphate 3 epimerase family 15 208 2.5E-39 T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CU254_RS41020 5a4b58efbc999aaf428b922560df1eb0 240 SUPERFAMILY SSF51366 17 222 8.37E-43 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CU254_RS17015 ca30384a1da26a8991e12bb9862c04a0 436 Gene3D G3DSA:1.20.1250.20 226 411 4.3E-19 T 28-03-2018 CU254_RS17015 ca30384a1da26a8991e12bb9862c04a0 436 Pfam PF07690 Major Facilitator Superfamily 57 372 3.9E-20 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS17015 ca30384a1da26a8991e12bb9862c04a0 436 SUPERFAMILY SSF103473 34 408 1.11E-40 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS17015 ca30384a1da26a8991e12bb9862c04a0 436 Gene3D G3DSA:1.20.1250.20 36 224 5.9E-16 T 28-03-2018 CU254_RS32910 42cced44e7f3d687a98fdded75db1a45 241 Pfam PF12079 Protein of unknown function (DUF3558) 51 236 1.0E-28 T 28-03-2018 IPR024520 Protein of unknown function DUF3558 CU254_RS22545 d6fbc60988f0f7b3be7a76f4ee548c4c 531 SUPERFAMILY SSF51556 55 292 7.42E-74 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS22545 d6fbc60988f0f7b3be7a76f4ee548c4c 531 SUPERFAMILY SSF51556 335 465 7.42E-74 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS22545 d6fbc60988f0f7b3be7a76f4ee548c4c 531 Gene3D G3DSA:2.30.40.10 1 68 3.1E-17 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS22545 d6fbc60988f0f7b3be7a76f4ee548c4c 531 Gene3D G3DSA:2.30.40.10 448 523 2.7E-5 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS22545 d6fbc60988f0f7b3be7a76f4ee548c4c 531 Gene3D G3DSA:3.20.20.140 69 447 1.2E-84 T 28-03-2018 CU254_RS22545 d6fbc60988f0f7b3be7a76f4ee548c4c 531 Pfam PF07969 Amidohydrolase family 43 507 8.1E-46 T 28-03-2018 IPR013108 Amidohydrolase 3 CU254_RS22545 d6fbc60988f0f7b3be7a76f4ee548c4c 531 SUPERFAMILY SSF51338 465 518 4.98E-17 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS22545 d6fbc60988f0f7b3be7a76f4ee548c4c 531 SUPERFAMILY SSF51338 1 54 4.98E-17 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS07180 af52b74004dd3c7e4c3d0751a92851b5 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 4.2E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS07180 af52b74004dd3c7e4c3d0751a92851b5 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 4.2E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS07180 af52b74004dd3c7e4c3d0751a92851b5 210 SUPERFAMILY SSF48498 81 197 4.45E-23 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS07180 af52b74004dd3c7e4c3d0751a92851b5 210 SUPERFAMILY SSF46689 13 75 2.74E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS07180 af52b74004dd3c7e4c3d0751a92851b5 210 Gene3D G3DSA:1.10.10.10 51 81 1.5E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS07180 af52b74004dd3c7e4c3d0751a92851b5 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 68 5.0E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS07180 af52b74004dd3c7e4c3d0751a92851b5 210 Gene3D G3DSA:1.10.10.60 7 50 2.2E-16 T 28-03-2018 CU254_RS07180 af52b74004dd3c7e4c3d0751a92851b5 210 Gene3D G3DSA:1.10.357.10 82 200 8.5E-22 T 28-03-2018 CU254_RS07180 af52b74004dd3c7e4c3d0751a92851b5 210 Pfam PF16859 Bacterial transcriptional repressor C-terminal 79 186 1.2E-27 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS22380 70b8e718dad457b841eff2c73750a460 272 Gene3D G3DSA:3.40.50.150 65 270 5.0E-54 T 28-03-2018 CU254_RS22380 70b8e718dad457b841eff2c73750a460 272 Pfam PF01479 S4 domain 6 47 3.0E-7 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CU254_RS22380 70b8e718dad457b841eff2c73750a460 272 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 6 241 4.7E-58 T 28-03-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 CU254_RS22380 70b8e718dad457b841eff2c73750a460 272 PIRSF PIRSF005578 1 268 2.7E-93 T 28-03-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 CU254_RS22380 70b8e718dad457b841eff2c73750a460 272 SUPERFAMILY SSF55174 5 59 7.65E-11 T 28-03-2018 CU254_RS22380 70b8e718dad457b841eff2c73750a460 272 Gene3D G3DSA:3.10.290.10 1 64 2.3E-15 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CU254_RS22380 70b8e718dad457b841eff2c73750a460 272 SMART SM00363 5 71 8.4E-5 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CU254_RS22380 70b8e718dad457b841eff2c73750a460 272 Pfam PF01728 FtsJ-like methyltransferase 63 247 4.9E-20 T 28-03-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 CU254_RS22380 70b8e718dad457b841eff2c73750a460 272 SUPERFAMILY SSF53335 61 248 1.33E-23 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS25385 103a0480548da9772b3c313dce10775e 390 ProSitePatterns PS00375 UDP-glycosyltransferases signature. 282 323 - T 28-03-2018 IPR035595 UDP-glycosyltransferase family, conserved site Reactome: R-HSA-156588 CU254_RS25385 103a0480548da9772b3c313dce10775e 390 Gene3D G3DSA:3.40.50.2000 207 374 7.1E-38 T 28-03-2018 CU254_RS25385 103a0480548da9772b3c313dce10775e 390 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 224 363 8.2E-19 T 28-03-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 Reactome: R-HSA-156588 CU254_RS25385 103a0480548da9772b3c313dce10775e 390 SUPERFAMILY SSF53756 1 388 2.27E-64 T 28-03-2018 CU254_RS25385 103a0480548da9772b3c313dce10775e 390 Gene3D G3DSA:3.40.50.2000 1 206 4.0E-22 T 28-03-2018 CU254_RS32855 d16ce9c3f59085162dc3d3c669715e54 207 SUPERFAMILY SSF56281 22 200 5.24E-46 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS32855 d16ce9c3f59085162dc3d3c669715e54 207 SMART SM00849 24 188 5.2E-37 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS32855 d16ce9c3f59085162dc3d3c669715e54 207 Pfam PF00753 Metallo-beta-lactamase superfamily 25 188 5.1E-23 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS32855 d16ce9c3f59085162dc3d3c669715e54 207 Gene3D G3DSA:3.60.15.10 13 205 1.2E-34 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS28805 deac6812368b6cda7820a69c7da62d42 202 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 142 156 5.6E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS28805 deac6812368b6cda7820a69c7da62d42 202 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 172 5.6E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS28805 deac6812368b6cda7820a69c7da62d42 202 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 172 184 5.6E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS28805 deac6812368b6cda7820a69c7da62d42 202 SMART SM00421 139 196 1.4E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS28805 deac6812368b6cda7820a69c7da62d42 202 Gene3D G3DSA:3.40.50.2300 2 127 1.3E-32 T 28-03-2018 CU254_RS28805 deac6812368b6cda7820a69c7da62d42 202 SUPERFAMILY SSF52172 3 131 6.83E-29 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS28805 deac6812368b6cda7820a69c7da62d42 202 SMART SM00448 3 116 7.9E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS28805 deac6812368b6cda7820a69c7da62d42 202 Pfam PF00196 Bacterial regulatory proteins, luxR family 141 196 4.1E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS28805 deac6812368b6cda7820a69c7da62d42 202 Gene3D G3DSA:1.10.10.10 128 202 4.5E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS28805 deac6812368b6cda7820a69c7da62d42 202 SUPERFAMILY SSF46894 130 202 3.16E-17 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS28805 deac6812368b6cda7820a69c7da62d42 202 Pfam PF00072 Response regulator receiver domain 5 117 4.3E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS31860 3f4acd85dbd2cdd0b70bbbedcaf70d44 304 SUPERFAMILY SSF159659 5 267 2.48E-87 T 28-03-2018 CU254_RS31860 3f4acd85dbd2cdd0b70bbbedcaf70d44 304 PIRSF PIRSF028754 6 304 8.8E-97 T 28-03-2018 IPR008492 Protein of unknown function DUF774 CU254_RS31860 3f4acd85dbd2cdd0b70bbbedcaf70d44 304 Pfam PF09754 PAC2 family 26 243 4.1E-45 T 28-03-2018 IPR019151 Proteasome assembly chaperone 2 CU254_RS31860 3f4acd85dbd2cdd0b70bbbedcaf70d44 304 Gene3D G3DSA:1.10.287.100 225 265 2.0E-15 T 28-03-2018 CU254_RS26455 ff366375242cb3f020ad8736d634e0ed 125 Pfam PF01230 HIT domain 17 113 1.7E-26 T 28-03-2018 IPR001310 Histidine triad (HIT) protein CU254_RS26455 ff366375242cb3f020ad8736d634e0ed 125 PRINTS PR00332 Histidine triad family signature 99 109 2.9E-17 T 28-03-2018 IPR001310 Histidine triad (HIT) protein CU254_RS26455 ff366375242cb3f020ad8736d634e0ed 125 PRINTS PR00332 Histidine triad family signature 10 26 2.9E-17 T 28-03-2018 IPR001310 Histidine triad (HIT) protein CU254_RS26455 ff366375242cb3f020ad8736d634e0ed 125 PRINTS PR00332 Histidine triad family signature 31 49 2.9E-17 T 28-03-2018 IPR001310 Histidine triad (HIT) protein CU254_RS26455 ff366375242cb3f020ad8736d634e0ed 125 SUPERFAMILY SSF54197 8 112 8.35E-31 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CU254_RS26455 ff366375242cb3f020ad8736d634e0ed 125 Gene3D G3DSA:3.30.428.10 2 111 1.9E-28 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CU254_RS18040 d436a8af09851dfd20245694656d120a 313 Pfam PF16868 NMT1-like family 33 309 7.8E-47 T 28-03-2018 IPR011852 TRAP transporter solute receptor, TAXI family CU254_RS18040 d436a8af09851dfd20245694656d120a 313 SUPERFAMILY SSF53850 27 309 3.84E-50 T 28-03-2018 CU254_RS18040 d436a8af09851dfd20245694656d120a 313 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 8 309 8.2E-59 T 28-03-2018 IPR011852 TRAP transporter solute receptor, TAXI family CU254_RS18040 d436a8af09851dfd20245694656d120a 313 Gene3D G3DSA:3.40.190.10 162 311 3.2E-28 T 28-03-2018 CU254_RS18040 d436a8af09851dfd20245694656d120a 313 Gene3D G3DSA:3.40.190.10 26 161 4.2E-14 T 28-03-2018 CU254_RS00595 ba1f38787a4e59b31f24bc6987cb8589 452 ProSitePatterns PS00216 Sugar transport proteins signature 1. 303 320 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CU254_RS00595 ba1f38787a4e59b31f24bc6987cb8589 452 Pfam PF00083 Sugar (and other) transporter 22 236 2.0E-25 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CU254_RS00595 ba1f38787a4e59b31f24bc6987cb8589 452 Gene3D G3DSA:1.20.1250.20 230 446 2.6E-27 T 28-03-2018 CU254_RS00595 ba1f38787a4e59b31f24bc6987cb8589 452 Pfam PF07690 Major Facilitator Superfamily 256 433 3.6E-16 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS00595 ba1f38787a4e59b31f24bc6987cb8589 452 SUPERFAMILY SSF103473 12 439 1.57E-62 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS00595 ba1f38787a4e59b31f24bc6987cb8589 452 Gene3D G3DSA:1.20.1250.20 16 229 9.8E-22 T 28-03-2018 CU254_RS00595 ba1f38787a4e59b31f24bc6987cb8589 452 ProSitePatterns PS00217 Sugar transport proteins signature 2. 132 157 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CU254_RS28940 e63283aeff76a802141e9abab2146ac3 316 Gene3D G3DSA:2.60.260.20 137 209 9.7E-16 T 28-03-2018 CU254_RS28940 e63283aeff76a802141e9abab2146ac3 316 SUPERFAMILY SSF49493 135 214 2.62E-14 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CU254_RS28940 e63283aeff76a802141e9abab2146ac3 316 Gene3D G3DSA:1.10.287.110 2 123 1.7E-34 T 28-03-2018 IPR001623 DnaJ domain CU254_RS28940 e63283aeff76a802141e9abab2146ac3 316 PRINTS PR00625 DnaJ domain signature 26 41 2.0E-25 T 28-03-2018 IPR001623 DnaJ domain CU254_RS28940 e63283aeff76a802141e9abab2146ac3 316 PRINTS PR00625 DnaJ domain signature 42 62 2.0E-25 T 28-03-2018 IPR001623 DnaJ domain CU254_RS28940 e63283aeff76a802141e9abab2146ac3 316 PRINTS PR00625 DnaJ domain signature 62 81 2.0E-25 T 28-03-2018 IPR001623 DnaJ domain CU254_RS28940 e63283aeff76a802141e9abab2146ac3 316 PRINTS PR00625 DnaJ domain signature 8 26 2.0E-25 T 28-03-2018 IPR001623 DnaJ domain CU254_RS28940 e63283aeff76a802141e9abab2146ac3 316 Pfam PF00226 DnaJ domain 6 67 3.1E-27 T 28-03-2018 IPR001623 DnaJ domain CU254_RS28940 e63283aeff76a802141e9abab2146ac3 316 SUPERFAMILY SSF49493 216 301 6.93E-18 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CU254_RS28940 e63283aeff76a802141e9abab2146ac3 316 Gene3D G3DSA:2.60.260.20 211 314 3.9E-22 T 28-03-2018 CU254_RS28940 e63283aeff76a802141e9abab2146ac3 316 SMART SM00271 5 62 9.4E-31 T 28-03-2018 IPR001623 DnaJ domain CU254_RS28940 e63283aeff76a802141e9abab2146ac3 316 SUPERFAMILY SSF46565 2 129 8.24E-33 T 28-03-2018 IPR001623 DnaJ domain CU254_RS28940 e63283aeff76a802141e9abab2146ac3 316 Pfam PF01556 DnaJ C terminal domain 143 290 3.7E-29 T 28-03-2018 IPR002939 Chaperone DnaJ, C-terminal CU254_RS13020 0fa78d4a6666f9297edac304000e5bc4 325 Pfam PF00704 Glycosyl hydrolases family 18 46 255 6.9E-10 T 28-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 CU254_RS13020 0fa78d4a6666f9297edac304000e5bc4 325 SUPERFAMILY SSF51445 45 303 1.09E-19 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS13020 0fa78d4a6666f9297edac304000e5bc4 325 Gene3D G3DSA:3.20.20.80 43 317 4.7E-27 T 28-03-2018 CU254_RS22355 719bb93a7010d678e90cf22ac2bc18c1 315 Pfam PF11382 Copper transport outer membrane protein, MctB 2 308 4.2E-99 T 28-03-2018 IPR021522 Copper transporter MctB GO:0006810 CU254_RS03040 0096e294c3b071b1107af470f45890dd 215 Gene3D G3DSA:1.10.10.10 119 214 9.4E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS03040 0096e294c3b071b1107af470f45890dd 215 Pfam PF00072 Response regulator receiver domain 1 111 6.4E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS03040 0096e294c3b071b1107af470f45890dd 215 Gene3D G3DSA:3.40.50.2300 1 118 2.4E-29 T 28-03-2018 CU254_RS03040 0096e294c3b071b1107af470f45890dd 215 Pfam PF00486 Transcriptional regulatory protein, C terminal 143 212 1.3E-13 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS03040 0096e294c3b071b1107af470f45890dd 215 SUPERFAMILY SSF52172 1 116 3.13E-33 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS03040 0096e294c3b071b1107af470f45890dd 215 SMART SM00862 143 212 1.0E-15 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS03040 0096e294c3b071b1107af470f45890dd 215 SUPERFAMILY SSF46894 126 212 2.58E-15 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS03040 0096e294c3b071b1107af470f45890dd 215 SMART SM00448 1 110 3.0E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS32750 06de11e2d814f4e0093ab94e7ee73e09 167 SUPERFAMILY SSF46767 86 165 1.96E-24 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CU254_RS32750 06de11e2d814f4e0093ab94e7ee73e09 167 Gene3D G3DSA:1.10.10.10 78 167 2.2E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS32750 06de11e2d814f4e0093ab94e7ee73e09 167 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 86 165 7.0E-25 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CU254_RS32750 06de11e2d814f4e0093ab94e7ee73e09 167 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 135 141 - T 28-03-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CU254_RS32750 06de11e2d814f4e0093ab94e7ee73e09 167 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 86 164 8.3E-27 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CU254_RS38300 61ffb9af21feeb531f7bfa7d3ac42ba4 144 Pfam PF13411 MerR HTH family regulatory protein 21 86 1.2E-15 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS38300 61ffb9af21feeb531f7bfa7d3ac42ba4 144 ProSitePatterns PS00552 MerR-type HTH domain signature. 22 44 - T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS38300 61ffb9af21feeb531f7bfa7d3ac42ba4 144 SMART SM00422 19 88 1.6E-23 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS38300 61ffb9af21feeb531f7bfa7d3ac42ba4 144 Gene3D G3DSA:1.10.1660.10 9 134 2.0E-23 T 28-03-2018 CU254_RS38300 61ffb9af21feeb531f7bfa7d3ac42ba4 144 SUPERFAMILY SSF46955 20 107 6.41E-19 T 28-03-2018 IPR009061 Putative DNA-binding domain CU254_RS35700 bfb7cfaadb6052cb905d769ddee9be5f 144 Gene3D G3DSA:1.10.10.10 2 144 1.9E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS35700 bfb7cfaadb6052cb905d769ddee9be5f 144 Pfam PF12802 MarR family 37 94 7.0E-16 T 28-03-2018 CU254_RS35700 bfb7cfaadb6052cb905d769ddee9be5f 144 SMART SM00347 31 130 3.0E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS35700 bfb7cfaadb6052cb905d769ddee9be5f 144 SUPERFAMILY SSF46785 7 142 8.65E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS01955 c2df8ec0ab27ece2a09bddc5299565ad 229 SUPERFAMILY SSF52166 1 204 1.83E-71 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CU254_RS01955 c2df8ec0ab27ece2a09bddc5299565ad 229 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 17 202 4.2E-69 T 28-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS01955 c2df8ec0ab27ece2a09bddc5299565ad 229 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 9 208 32.091 T 28-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS01955 c2df8ec0ab27ece2a09bddc5299565ad 229 Pfam PF00573 Ribosomal protein L4/L1 family 17 203 9.3E-61 T 28-03-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 CU254_RS01955 c2df8ec0ab27ece2a09bddc5299565ad 229 Gene3D G3DSA:3.40.1370.10 2 148 4.2E-50 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CU254_RS01955 c2df8ec0ab27ece2a09bddc5299565ad 229 Gene3D G3DSA:3.40.1370.10 149 204 2.3E-11 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CU254_RS35760 947d733f8d767cc9d2457f1d92371a94 408 SUPERFAMILY SSF53623 43 278 1.11E-33 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CU254_RS35760 947d733f8d767cc9d2457f1d92371a94 408 Gene3D G3DSA:3.40.1190.10 43 282 3.4E-42 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CU254_RS35760 947d733f8d767cc9d2457f1d92371a94 408 Pfam PF08245 Mur ligase middle domain 57 262 2.3E-13 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CU254_RS35760 947d733f8d767cc9d2457f1d92371a94 408 Pfam PF08353 Domain of unknown function (DUF1727) 300 398 5.4E-23 T 28-03-2018 IPR013564 Domain of unknown function DUF1727 CU254_RS27870 eb6d2a86fa3aefdc9e8c4c337985a922 239 Pfam PF02308 MgtC family 18 146 3.5E-35 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CU254_RS27870 eb6d2a86fa3aefdc9e8c4c337985a922 239 PRINTS PR01837 MgtC/SapB protein signature 73 95 1.1E-42 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CU254_RS27870 eb6d2a86fa3aefdc9e8c4c337985a922 239 PRINTS PR01837 MgtC/SapB protein signature 100 124 1.1E-42 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CU254_RS27870 eb6d2a86fa3aefdc9e8c4c337985a922 239 PRINTS PR01837 MgtC/SapB protein signature 20 39 1.1E-42 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CU254_RS27870 eb6d2a86fa3aefdc9e8c4c337985a922 239 PRINTS PR01837 MgtC/SapB protein signature 39 57 1.1E-42 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CU254_RS27870 eb6d2a86fa3aefdc9e8c4c337985a922 239 Gene3D G3DSA:3.30.70.260 156 230 2.0E-4 T 28-03-2018 CU254_RS39465 789790b27afe93accba2c4ef8063ccab 438 SUPERFAMILY SSF51971 251 307 4.12E-54 T 28-03-2018 CU254_RS39465 789790b27afe93accba2c4ef8063ccab 438 SUPERFAMILY SSF51971 1 202 4.12E-54 T 28-03-2018 CU254_RS39465 789790b27afe93accba2c4ef8063ccab 438 SUPERFAMILY SSF51971 282 434 2.88E-9 T 28-03-2018 CU254_RS39465 789790b27afe93accba2c4ef8063ccab 438 Gene3D G3DSA:3.50.50.60 1 87 7.9E-10 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS39465 789790b27afe93accba2c4ef8063ccab 438 PRINTS PR00419 Adrenodoxin reductase family signature 136 150 9.3E-8 T 28-03-2018 CU254_RS39465 789790b27afe93accba2c4ef8063ccab 438 PRINTS PR00419 Adrenodoxin reductase family signature 65 75 9.3E-8 T 28-03-2018 CU254_RS39465 789790b27afe93accba2c4ef8063ccab 438 PRINTS PR00419 Adrenodoxin reductase family signature 22 35 9.3E-8 T 28-03-2018 CU254_RS39465 789790b27afe93accba2c4ef8063ccab 438 Gene3D G3DSA:3.50.50.60 88 307 4.2E-61 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS39465 789790b27afe93accba2c4ef8063ccab 438 PIRSF PIRSF000362 1 438 5.5E-163 T 28-03-2018 IPR021163 Ferredoxin-NADP+ reductase, adrenodoxin-type GO:0016491|GO:0055114 Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 CU254_RS39465 789790b27afe93accba2c4ef8063ccab 438 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 1 158 9.1E-8 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS16910 f58e2c79f0074dec4fb378b4d2bc5577 245 Gene3D G3DSA:3.40.50.620 4 185 2.7E-39 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS16910 f58e2c79f0074dec4fb378b4d2bc5577 245 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 20 84 6.2E-9 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CU254_RS16910 f58e2c79f0074dec4fb378b4d2bc5577 245 SUPERFAMILY SSF52374 18 174 5.33E-30 T 28-03-2018 CU254_RS16910 f58e2c79f0074dec4fb378b4d2bc5577 245 Pfam PF06574 FAD synthetase 18 157 6.4E-41 T 28-03-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 CU254_RS07860 303b052052271aaa6e367bb4e4e656ea 594 SUPERFAMILY SSF140453 93 143 6.02E-7 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CU254_RS07860 303b052052271aaa6e367bb4e4e656ea 594 Gene3D G3DSA:1.10.287.850 85 199 4.7E-11 T 28-03-2018 CU254_RS04360 1cc60a136dba884bcd40d17cd767dbaf 473 Pfam PF13556 PucR C-terminal helix-turn-helix domain 416 471 1.8E-17 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CU254_RS04360 1cc60a136dba884bcd40d17cd767dbaf 473 Gene3D G3DSA:1.10.10.60 395 453 2.7E-4 T 28-03-2018 CU254_RS04360 1cc60a136dba884bcd40d17cd767dbaf 473 Gene3D G3DSA:3.40.1390.20 2 122 6.7E-4 T 28-03-2018 IPR028979 HPr(Ser) kinase/phosphorylase, N-terminal domain-like CU254_RS04360 1cc60a136dba884bcd40d17cd767dbaf 473 Pfam PF07905 Purine catabolism regulatory protein-like family 9 122 2.4E-33 T 28-03-2018 IPR012914 Purine catabolism PurC-like domain CU254_RS25550 ee9a2c75bde289a1aebd5cb5e6d98915 580 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 169 184 1.5E-48 T 28-03-2018 CU254_RS25550 ee9a2c75bde289a1aebd5cb5e6d98915 580 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 352 368 1.5E-48 T 28-03-2018 CU254_RS25550 ee9a2c75bde289a1aebd5cb5e6d98915 580 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 316 332 1.5E-48 T 28-03-2018 CU254_RS25550 ee9a2c75bde289a1aebd5cb5e6d98915 580 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 1.5E-48 T 28-03-2018 CU254_RS25550 ee9a2c75bde289a1aebd5cb5e6d98915 580 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 334 352 1.5E-48 T 28-03-2018 CU254_RS25550 ee9a2c75bde289a1aebd5cb5e6d98915 580 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 301 316 1.5E-48 T 28-03-2018 CU254_RS25550 ee9a2c75bde289a1aebd5cb5e6d98915 580 Pfam PF01494 FAD binding domain 5 367 1.5E-114 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CU254_RS25550 ee9a2c75bde289a1aebd5cb5e6d98915 580 SUPERFAMILY SSF51905 5 190 5.99E-57 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS25550 ee9a2c75bde289a1aebd5cb5e6d98915 580 SUPERFAMILY SSF51905 288 379 5.99E-57 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS25550 ee9a2c75bde289a1aebd5cb5e6d98915 580 Gene3D G3DSA:3.50.50.60 4 431 1.5E-63 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS03890 3dce738938b476112f0210887099e931 167 SUPERFAMILY SSF54637 2 151 2.77E-45 T 28-03-2018 IPR029069 HotDog domain CU254_RS03890 3dce738938b476112f0210887099e931 167 Gene3D G3DSA:3.10.129.10 1 150 7.5E-32 T 28-03-2018 CU254_RS03890 3dce738938b476112f0210887099e931 167 Pfam PF01575 MaoC like domain 12 118 1.2E-15 T 28-03-2018 IPR002539 MaoC-like domain CU254_RS36835 62483d37ec438b6046ca7cbccb2813a3 98 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 75 17.778 T 28-03-2018 IPR003482 Transcription factor WhiB CU254_RS36835 62483d37ec438b6046ca7cbccb2813a3 98 Pfam PF02467 Transcription factor WhiB 8 70 6.3E-23 T 28-03-2018 IPR034768 WhiB-like iron-sulfur binding domain CU254_RS18540 837defe053cf7468dbfd8d88523c53d8 410 Gene3D G3DSA:1.20.1250.20 188 402 2.7E-22 T 28-03-2018 CU254_RS18540 837defe053cf7468dbfd8d88523c53d8 410 Pfam PF07690 Major Facilitator Superfamily 3 352 2.0E-39 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS18540 837defe053cf7468dbfd8d88523c53d8 410 Gene3D G3DSA:1.20.1250.20 1 183 3.7E-24 T 28-03-2018 CU254_RS18540 837defe053cf7468dbfd8d88523c53d8 410 SUPERFAMILY SSF103473 2 396 6.93E-58 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS12405 934d7136bd30322ec58babff54eebb9a 82 SUPERFAMILY SSF51230 4 79 3.4E-18 T 28-03-2018 IPR011053 Single hybrid motif CU254_RS12405 934d7136bd30322ec58babff54eebb9a 82 Gene3D G3DSA:2.40.50.100 4 33 0.32 T 28-03-2018 CU254_RS12405 934d7136bd30322ec58babff54eebb9a 82 Gene3D G3DSA:2.40.50.100 59 82 0.0019 T 28-03-2018 CU254_RS12405 934d7136bd30322ec58babff54eebb9a 82 Gene3D G3DSA:2.40.50.100 34 58 1.5E-5 T 28-03-2018 CU254_RS12405 934d7136bd30322ec58babff54eebb9a 82 Pfam PF00364 Biotin-requiring enzyme 5 78 1.4E-13 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CU254_RS12405 934d7136bd30322ec58babff54eebb9a 82 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 8 21 1.5E-6 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CU254_RS12405 934d7136bd30322ec58babff54eebb9a 82 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 40 53 1.5E-6 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CU254_RS12405 934d7136bd30322ec58babff54eebb9a 82 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 25 39 1.5E-6 T 28-03-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 CU254_RS14465 a7d5213fa05dc43256fec12623801730 195 Gene3D G3DSA:3.40.1580.10 21 170 3.5E-11 T 28-03-2018 CU254_RS14465 a7d5213fa05dc43256fec12623801730 195 SUPERFAMILY SSF160631 4 153 1.12E-11 T 28-03-2018 CU254_RS33290 e9146913f0c493fb5a026fc7028470f9 264 SUPERFAMILY SSF56112 9 239 8.98E-13 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS33290 e9146913f0c493fb5a026fc7028470f9 264 Gene3D G3DSA:3.90.1200.10 80 256 3.0E-6 T 28-03-2018 CU254_RS33290 e9146913f0c493fb5a026fc7028470f9 264 TIGRFAM TIGR02569 TIGR02569_actnb: TIGR02569 family protein 1 252 2.1E-45 T 28-03-2018 IPR013402 Conserved hypothetical protein CHP02569 CU254_RS06290 c4d5f87f8cd0870df040b976aa4fdbcb 285 Gene3D G3DSA:1.20.1260.10 35 285 1.3E-59 T 28-03-2018 IPR012347 Ferritin-related CU254_RS06290 c4d5f87f8cd0870df040b976aa4fdbcb 285 Pfam PF05138 Phenylacetic acid catabolic protein 43 285 8.4E-73 T 28-03-2018 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 CU254_RS06290 c4d5f87f8cd0870df040b976aa4fdbcb 285 SUPERFAMILY SSF47240 43 279 6.22E-59 T 28-03-2018 IPR009078 Ferritin-like superfamily CU254_RS06290 c4d5f87f8cd0870df040b976aa4fdbcb 285 TIGRFAM TIGR02158 PA_CoA_Oxy3: phenylacetate-CoA oxygenase, PaaI subunit 51 285 4.3E-66 T 28-03-2018 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 CU254_RS01030 b92b3867d8134d760e0a533a21c56ddb 266 Gene3D G3DSA:3.10.450.50 28 145 8.6E-5 T 28-03-2018 CU254_RS01030 b92b3867d8134d760e0a533a21c56ddb 266 Gene3D G3DSA:3.10.450.50 146 266 0.028 T 28-03-2018 CU254_RS36800 83d85fe00c1ecdf12a90d881532c086a 394 Gene3D G3DSA:1.10.10.10 1 323 0.24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS34275 21e8a28a987428fcc05250b957f8c5e1 143 SUPERFAMILY SSF48498 36 141 8.45E-25 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS34275 21e8a28a987428fcc05250b957f8c5e1 143 Gene3D G3DSA:1.10.357.10 18 143 2.9E-27 T 28-03-2018 CU254_RS30780 cec6acf11619d42f450735ea9d11a9c4 486 SUPERFAMILY SSF52794 2 98 5.41E-31 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CU254_RS30780 cec6acf11619d42f450735ea9d11a9c4 486 Gene3D G3DSA:3.40.50.2300 2 100 4.2E-37 T 28-03-2018 CU254_RS30780 cec6acf11619d42f450735ea9d11a9c4 486 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 5 94 2.8E-20 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CU254_RS30780 cec6acf11619d42f450735ea9d11a9c4 486 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 4 87 1.7E-29 T 28-03-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202|KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 CU254_RS30780 cec6acf11619d42f450735ea9d11a9c4 486 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 124 464 4.2E-113 T 28-03-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 CU254_RS07700 adfc4bfa3b98d963919caaf9d16f4621 33 TIGRFAM TIGR02115 potass_kdpF: K+-transporting ATPase, F subunit 11 33 1.5E-10 T 28-03-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 CU254_RS07700 adfc4bfa3b98d963919caaf9d16f4621 33 Pfam PF09604 F subunit of K+-transporting ATPase (Potass_KdpF) 10 33 1.3E-10 T 28-03-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 CU254_RS14130 ba554192097db183999e6cb12c1afafd 272 SUPERFAMILY SSF51679 7 268 3.2E-31 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS14130 ba554192097db183999e6cb12c1afafd 272 Gene3D G3DSA:3.20.20.30 3 207 8.1E-30 T 28-03-2018 CU254_RS14130 ba554192097db183999e6cb12c1afafd 272 Pfam PF00296 Luciferase-like monooxygenase 19 201 5.4E-24 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS32480 b9d23093ff3ee7f51fa77132139674d4 300 Gene3D G3DSA:3.40.50.720 1 155 4.0E-20 T 28-03-2018 CU254_RS32480 b9d23093ff3ee7f51fa77132139674d4 300 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 212 1.4E-15 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CU254_RS32480 b9d23093ff3ee7f51fa77132139674d4 300 Gene3D G3DSA:3.90.25.10 162 296 2.6E-17 T 28-03-2018 CU254_RS32480 b9d23093ff3ee7f51fa77132139674d4 300 SUPERFAMILY SSF51735 1 291 4.07E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS00025 d85815bdba0911de16332bce0c3fc452 252 Pfam PF01522 Polysaccharide deacetylase 72 191 5.7E-18 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CU254_RS00025 d85815bdba0911de16332bce0c3fc452 252 Gene3D G3DSA:3.20.20.370 51 252 5.9E-29 T 28-03-2018 CU254_RS00025 d85815bdba0911de16332bce0c3fc452 252 SUPERFAMILY SSF88713 64 251 3.71E-30 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CU254_RS22300 52453d49d3df8da41b46bb26e8eed974 349 Pfam PF13614 AAA domain 99 275 7.9E-63 T 28-03-2018 IPR025669 AAA domain CU254_RS22300 52453d49d3df8da41b46bb26e8eed974 349 SUPERFAMILY SSF52540 98 348 3.22E-66 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS22300 52453d49d3df8da41b46bb26e8eed974 349 Gene3D G3DSA:3.40.50.300 81 349 3.1E-63 T 28-03-2018 CU254_RS13135 af9d4ac734179ca73ddcb72cb0d1c3f1 144 SUPERFAMILY SSF46785 6 142 3.71E-34 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS13135 af9d4ac734179ca73ddcb72cb0d1c3f1 144 Pfam PF01047 MarR family 38 95 5.9E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS13135 af9d4ac734179ca73ddcb72cb0d1c3f1 144 SMART SM00347 31 131 5.3E-19 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS13135 af9d4ac734179ca73ddcb72cb0d1c3f1 144 Gene3D G3DSA:1.10.10.10 3 144 1.9E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS22570 b45f29defe2ab65dce43d649a51fa803 282 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 269 1.1E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS22570 b45f29defe2ab65dce43d649a51fa803 282 SUPERFAMILY SSF161098 4 282 3.27E-67 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS22570 b45f29defe2ab65dce43d649a51fa803 282 Gene3D G3DSA:1.10.3720.10 2 270 2.5E-45 T 28-03-2018 CU254_RS09910 7d2bdbb01b49314d2341fc5521bb65fc 61 Gene3D G3DSA:3.30.70.20 1 61 2.9E-6 T 28-03-2018 CU254_RS09910 7d2bdbb01b49314d2341fc5521bb65fc 61 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 5 56 6.5E-12 T 28-03-2018 CU254_RS09910 7d2bdbb01b49314d2341fc5521bb65fc 61 SUPERFAMILY SSF54862 3 59 2.39E-9 T 28-03-2018 CU254_RS26635 42fb588199a586b0baf48472e1ff1010 257 Gene3D G3DSA:1.10.12.10 214 255 1.1E-15 T 28-03-2018 IPR014748 Crontonase, C-terminal CU254_RS26635 42fb588199a586b0baf48472e1ff1010 257 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 253 3.6E-50 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CU254_RS26635 42fb588199a586b0baf48472e1ff1010 257 SUPERFAMILY SSF52096 3 255 7.47E-72 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS26635 42fb588199a586b0baf48472e1ff1010 257 Gene3D G3DSA:3.90.226.10 5 213 6.3E-59 T 28-03-2018 CU254_RS01660 6f84ad711f6c233ebd2122e8553e74aa 281 Pfam PF04672 S-adenosyl methyltransferase 14 280 2.7E-73 T 28-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CU254_RS01660 6f84ad711f6c233ebd2122e8553e74aa 281 SUPERFAMILY SSF53335 18 261 2.14E-43 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS01660 6f84ad711f6c233ebd2122e8553e74aa 281 Gene3D G3DSA:3.40.50.150 1 281 3.8E-44 T 28-03-2018 CU254_RS01660 6f84ad711f6c233ebd2122e8553e74aa 281 PIRSF PIRSF017393 3 281 1.6E-79 T 28-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CU254_RS02720 ba9544525b2b6689ba52b4cb999204ee 121 PIRSF PIRSF016498 1 121 1.6E-19 T 28-03-2018 IPR018699 Protein of unknown function DUF2203 CU254_RS02720 ba9544525b2b6689ba52b4cb999204ee 121 Pfam PF09969 Uncharacterized conserved protein (DUF2203) 3 119 1.8E-31 T 28-03-2018 IPR018699 Protein of unknown function DUF2203 CU254_RS00935 47c37da5a46bcee2afad0d384c6e76e7 341 SUPERFAMILY SSF50129 11 143 5.66E-40 T 28-03-2018 IPR011032 GroES-like CU254_RS00935 47c37da5a46bcee2afad0d384c6e76e7 341 Gene3D G3DSA:3.40.50.720 154 281 1.1E-31 T 28-03-2018 CU254_RS00935 47c37da5a46bcee2afad0d384c6e76e7 341 Pfam PF00107 Zinc-binding dehydrogenase 163 294 2.3E-24 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CU254_RS00935 47c37da5a46bcee2afad0d384c6e76e7 341 SUPERFAMILY SSF50129 293 338 8.95E-5 T 28-03-2018 IPR011032 GroES-like CU254_RS00935 47c37da5a46bcee2afad0d384c6e76e7 341 SMART SM00829 23 337 2.1E-9 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CU254_RS00935 47c37da5a46bcee2afad0d384c6e76e7 341 Pfam PF16884 N-terminal domain of oxidoreductase 12 117 1.4E-39 T 28-03-2018 CU254_RS00935 47c37da5a46bcee2afad0d384c6e76e7 341 SUPERFAMILY SSF51735 128 304 7.27E-53 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS00935 47c37da5a46bcee2afad0d384c6e76e7 341 Gene3D G3DSA:3.90.180.10 5 153 6.6E-38 T 28-03-2018 CU254_RS34700 c6999a31c4fb1295f8b0a27defe3b176 110 SUPERFAMILY SSF46946 63 109 1.01E-6 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CU254_RS34700 c6999a31c4fb1295f8b0a27defe3b176 110 PIRSF PIRSF002134 48 110 7.5E-4 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CU254_RS34700 c6999a31c4fb1295f8b0a27defe3b176 110 Gene3D G3DSA:1.10.8.50 42 110 1.2E-7 T 28-03-2018 CU254_RS23700 f1eb47c51281840aeef6263f4a3a3397 810 Pfam PF00550 Phosphopantetheine attachment site 2 61 8.2E-8 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS23700 f1eb47c51281840aeef6263f4a3a3397 810 Gene3D G3DSA:2.160.10.10 391 548 1.6E-12 T 28-03-2018 CU254_RS23700 f1eb47c51281840aeef6263f4a3a3397 810 Gene3D G3DSA:2.160.10.10 193 320 3.8E-13 T 28-03-2018 CU254_RS23700 f1eb47c51281840aeef6263f4a3a3397 810 Gene3D G3DSA:2.160.10.10 655 801 5.9E-17 T 28-03-2018 CU254_RS23700 f1eb47c51281840aeef6263f4a3a3397 810 SUPERFAMILY SSF47336 2 81 8.9E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS23700 f1eb47c51281840aeef6263f4a3a3397 810 SUPERFAMILY SSF51161 693 800 2.5E-17 T 28-03-2018 IPR011004 Trimeric LpxA-like CU254_RS23700 f1eb47c51281840aeef6263f4a3a3397 810 TIGRFAM TIGR02353 NRPS_term_dom: non-ribosomal peptide synthetase terminal domain of unknown function 92 796 1.6E-214 T 28-03-2018 IPR012728 Non-ribosomal peptide synthetase, C-terminal CU254_RS23700 f1eb47c51281840aeef6263f4a3a3397 810 SUPERFAMILY SSF51161 188 305 5.41E-12 T 28-03-2018 IPR011004 Trimeric LpxA-like CU254_RS23700 f1eb47c51281840aeef6263f4a3a3397 810 Gene3D G3DSA:1.10.1200.10 1 89 1.6E-14 T 28-03-2018 CU254_RS23700 f1eb47c51281840aeef6263f4a3a3397 810 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 747 775 0.012 T 28-03-2018 IPR001451 Hexapeptide repeat CU254_RS07820 4e30d1f647ee602b62ab1f59ba0b9915 202 Gene3D G3DSA:1.10.10.60 3 56 5.6E-13 T 28-03-2018 CU254_RS07820 4e30d1f647ee602b62ab1f59ba0b9915 202 Gene3D G3DSA:1.10.357.10 57 189 1.1E-22 T 28-03-2018 CU254_RS07820 4e30d1f647ee602b62ab1f59ba0b9915 202 SUPERFAMILY SSF48498 76 178 1.11E-20 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS07820 4e30d1f647ee602b62ab1f59ba0b9915 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 55 1.1E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS07820 4e30d1f647ee602b62ab1f59ba0b9915 202 SUPERFAMILY SSF46689 4 66 2.51E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS17575 a1389b9aaa95f2f8c14c0c63356ce4ef 317 Pfam PF12556 Cobaltochelatase CobS subunit N terminal 12 40 1.8E-11 T 28-03-2018 IPR025865 Cobaltochelatase subunit CobS N-terminal domain KEGG: 00860+6.6.1.2|MetaCyc: PWY-7376 CU254_RS17575 a1389b9aaa95f2f8c14c0c63356ce4ef 317 Pfam PF07728 AAA domain (dynein-related subfamily) 67 193 2.6E-12 T 28-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 CU254_RS17575 a1389b9aaa95f2f8c14c0c63356ce4ef 317 SUPERFAMILY SSF52540 37 280 7.38E-31 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS17575 a1389b9aaa95f2f8c14c0c63356ce4ef 317 Pfam PF08406 CbbQ/NirQ/NorQ C-terminal 225 289 1.3E-4 T 28-03-2018 IPR013615 CbbQ/NirQ/NorQ, C-terminal CU254_RS17575 a1389b9aaa95f2f8c14c0c63356ce4ef 317 Gene3D G3DSA:3.40.50.300 52 217 3.3E-17 T 28-03-2018 CU254_RS29250 6541ac16acd7ac70715d8efd83b048c2 458 Gene3D G3DSA:3.40.605.10 6 250 7.2E-78 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CU254_RS29250 6541ac16acd7ac70715d8efd83b048c2 458 SUPERFAMILY SSF53720 12 455 1.23E-140 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CU254_RS29250 6541ac16acd7ac70715d8efd83b048c2 458 Pfam PF00171 Aldehyde dehydrogenase family 16 455 6.6E-143 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CU254_RS29250 6541ac16acd7ac70715d8efd83b048c2 458 Gene3D G3DSA:3.40.309.10 251 442 2.7E-67 T 28-03-2018 CU254_RS29250 6541ac16acd7ac70715d8efd83b048c2 458 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 231 238 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CU254_RS29250 6541ac16acd7ac70715d8efd83b048c2 458 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 259 270 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CU254_RS24200 e9266d1839e7dddec688098cee71da3f 105 Gene3D G3DSA:1.10.287.1060 1 96 6.0E-5 T 28-03-2018 CU254_RS37490 0d6c6efc78c5f71cdc17ae04fbc0baad 203 SUPERFAMILY SSF50814 43 201 1.85E-41 T 28-03-2018 IPR012674 Calycin CU254_RS37490 0d6c6efc78c5f71cdc17ae04fbc0baad 203 Gene3D G3DSA:2.40.128.20 9 203 9.8E-66 T 28-03-2018 IPR012674 Calycin CU254_RS37490 0d6c6efc78c5f71cdc17ae04fbc0baad 203 Hamap MF_01297 UPF0678 fatty acid-binding protein-like protein . 40 202 33.033 T 28-03-2018 IPR022939 Uncharacterised protein family UPF0678 CU254_RS37490 0d6c6efc78c5f71cdc17ae04fbc0baad 203 Pfam PF08768 Domain of unknown function (DUF1794) 49 200 1.0E-49 T 28-03-2018 IPR014878 Domain of unknown function DUF1794 CU254_RS23180 a897a55dab98fe8a6d9a55d130b7c52f 638 Pfam PF07690 Major Facilitator Superfamily 265 437 1.6E-13 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS23180 a897a55dab98fe8a6d9a55d130b7c52f 638 Pfam PF07690 Major Facilitator Superfamily 470 631 5.0E-21 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS23180 a897a55dab98fe8a6d9a55d130b7c52f 638 Gene3D G3DSA:1.20.1250.20 446 636 3.2E-24 T 28-03-2018 CU254_RS23180 a897a55dab98fe8a6d9a55d130b7c52f 638 SUPERFAMILY SSF103473 232 634 2.35E-46 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS23180 a897a55dab98fe8a6d9a55d130b7c52f 638 Gene3D G3DSA:1.20.1250.20 238 438 1.5E-20 T 28-03-2018 CU254_RS25395 b4a69a53d5fdac0dd23b90fd1392ca7e 338 Pfam PF13377 Periplasmic binding protein-like domain 178 335 3.0E-38 T 28-03-2018 CU254_RS25395 b4a69a53d5fdac0dd23b90fd1392ca7e 338 Gene3D G3DSA:3.40.50.2300 185 337 1.1E-46 T 28-03-2018 CU254_RS25395 b4a69a53d5fdac0dd23b90fd1392ca7e 338 SUPERFAMILY SSF53822 68 327 1.19E-58 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CU254_RS25395 b4a69a53d5fdac0dd23b90fd1392ca7e 338 Gene3D G3DSA:1.10.260.40 13 64 5.3E-23 T 28-03-2018 CU254_RS25395 b4a69a53d5fdac0dd23b90fd1392ca7e 338 SUPERFAMILY SSF47413 12 70 2.55E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS25395 b4a69a53d5fdac0dd23b90fd1392ca7e 338 SMART SM00354 11 81 1.3E-24 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CU254_RS25395 b4a69a53d5fdac0dd23b90fd1392ca7e 338 Pfam PF00356 Bacterial regulatory proteins, lacI family 14 58 2.0E-17 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CU254_RS25395 b4a69a53d5fdac0dd23b90fd1392ca7e 338 ProSitePatterns PS00356 LacI-type HTH domain signature. 14 32 - T 28-03-2018 CU254_RS25395 b4a69a53d5fdac0dd23b90fd1392ca7e 338 Gene3D G3DSA:3.40.50.2300 65 184 6.9E-28 T 28-03-2018 CU254_RS24255 909c7b4be811097d877bbd7a1b1c41db 272 Gene3D G3DSA:3.40.50.1820 5 272 1.1E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS24255 909c7b4be811097d877bbd7a1b1c41db 272 SUPERFAMILY SSF53474 10 257 1.68E-41 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS24255 909c7b4be811097d877bbd7a1b1c41db 272 Pfam PF00561 alpha/beta hydrolase fold 25 257 2.5E-16 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS24255 909c7b4be811097d877bbd7a1b1c41db 272 PRINTS PR00412 Epoxide hydrolase signature 50 65 3.3E-5 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS24255 909c7b4be811097d877bbd7a1b1c41db 272 PRINTS PR00412 Epoxide hydrolase signature 107 120 3.3E-5 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS24255 909c7b4be811097d877bbd7a1b1c41db 272 PRINTS PR00412 Epoxide hydrolase signature 214 230 3.3E-5 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS24255 909c7b4be811097d877bbd7a1b1c41db 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 50 65 7.2E-10 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS24255 909c7b4be811097d877bbd7a1b1c41db 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 107 120 7.2E-10 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS24255 909c7b4be811097d877bbd7a1b1c41db 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 93 106 7.2E-10 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS24255 909c7b4be811097d877bbd7a1b1c41db 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 216 230 7.2E-10 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS08235 629a07b6c373ae824b71cf299ba25a4c 148 SUPERFAMILY SSF54534 65 138 1.96E-11 T 28-03-2018 CU254_RS08235 629a07b6c373ae824b71cf299ba25a4c 148 Gene3D G3DSA:1.10.287.180 30 60 0.13 T 28-03-2018 CU254_RS08235 629a07b6c373ae824b71cf299ba25a4c 148 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 68 137 4.9E-11 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CU254_RS08235 629a07b6c373ae824b71cf299ba25a4c 148 PIRSF PIRSF006092 10 140 5.6E-13 T 28-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 CU254_RS08235 629a07b6c373ae824b71cf299ba25a4c 148 Gene3D G3DSA:3.10.50.30 61 145 4.4E-15 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CU254_RS09185 a3a17ba897d20e7d70bd09d75e99db00 248 Pfam PF03130 PBS lyase HEAT-like repeat 125 151 0.021 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CU254_RS09185 a3a17ba897d20e7d70bd09d75e99db00 248 Gene3D G3DSA:1.25.40.70 171 240 6.7E-4 T 28-03-2018 CU254_RS09185 a3a17ba897d20e7d70bd09d75e99db00 248 Gene3D G3DSA:1.25.40.70 1 170 4.4E-6 T 28-03-2018 CU254_RS09185 a3a17ba897d20e7d70bd09d75e99db00 248 SUPERFAMILY SSF48371 115 214 3.96E-12 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 CU254_RS13725 32b36aa579333dc1c1cae4afa5573246 365 Pfam PF07690 Major Facilitator Superfamily 9 251 4.0E-26 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS13725 32b36aa579333dc1c1cae4afa5573246 365 Gene3D G3DSA:1.20.1250.20 189 363 2.4E-10 T 28-03-2018 CU254_RS13725 32b36aa579333dc1c1cae4afa5573246 365 SUPERFAMILY SSF103473 3 361 2.49E-44 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS13725 32b36aa579333dc1c1cae4afa5573246 365 Gene3D G3DSA:1.20.1250.20 2 188 4.2E-23 T 28-03-2018 CU254_RS41270 ff21f2d6bc3245a68161286b30d6661e 199 Pfam PF12079 Protein of unknown function (DUF3558) 7 194 1.7E-26 T 28-03-2018 IPR024520 Protein of unknown function DUF3558 CU254_RS37935 aa334f2e827a6506aa821e167a7b848b 407 Gene3D G3DSA:2.160.20.80 192 351 1.9E-13 T 28-03-2018 CU254_RS37935 aa334f2e827a6506aa821e167a7b848b 407 Pfam PF13576 Pentapeptide repeats (9 copies) 245 290 4.0E-7 T 28-03-2018 IPR001646 Pentapeptide repeat CU254_RS34710 0c764123ba3555174381c182a6c6e90b 434 SUPERFAMILY SSF53850 23 430 9.83E-65 T 28-03-2018 CU254_RS34710 0c764123ba3555174381c182a6c6e90b 434 Gene3D G3DSA:1.20.5.510 2 26 0.0011 T 28-03-2018 CU254_RS34710 0c764123ba3555174381c182a6c6e90b 434 Pfam PF01547 Bacterial extracellular solute-binding protein 64 336 1.1E-34 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 CU254_RS34710 0c764123ba3555174381c182a6c6e90b 434 Gene3D G3DSA:3.40.190.10 54 227 9.8E-36 T 28-03-2018 CU254_RS34710 0c764123ba3555174381c182a6c6e90b 434 Gene3D G3DSA:3.40.190.10 228 386 1.3E-8 T 28-03-2018 CU254_RS09315 6c3d2bfa41ac497b08fd2ce091eca4bd 520 Gene3D G3DSA:3.60.120.10 28 501 2.2E-167 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CU254_RS09315 6c3d2bfa41ac497b08fd2ce091eca4bd 520 PRINTS PR00095 Anthranilate synthase component I signature 353 366 1.3E-22 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CU254_RS09315 6c3d2bfa41ac497b08fd2ce091eca4bd 520 PRINTS PR00095 Anthranilate synthase component I signature 433 447 1.3E-22 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CU254_RS09315 6c3d2bfa41ac497b08fd2ce091eca4bd 520 PRINTS PR00095 Anthranilate synthase component I signature 339 352 1.3E-22 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CU254_RS09315 6c3d2bfa41ac497b08fd2ce091eca4bd 520 PRINTS PR00095 Anthranilate synthase component I signature 448 462 1.3E-22 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CU254_RS09315 6c3d2bfa41ac497b08fd2ce091eca4bd 520 SUPERFAMILY SSF56322 30 499 2.22E-157 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CU254_RS09315 6c3d2bfa41ac497b08fd2ce091eca4bd 520 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 41 499 1.6E-172 T 28-03-2018 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CU254_RS09315 6c3d2bfa41ac497b08fd2ce091eca4bd 520 Pfam PF04715 Anthranilate synthase component I, N terminal region 42 182 3.2E-32 T 28-03-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CU254_RS09315 6c3d2bfa41ac497b08fd2ce091eca4bd 520 Pfam PF00425 chorismate binding enzyme 237 491 1.1E-97 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal CU254_RS09745 de23830f41376617b38b51f5ce29bbca 337 SUPERFAMILY SSF101898 46 266 1.46E-9 T 28-03-2018 CU254_RS09745 de23830f41376617b38b51f5ce29bbca 337 Gene3D G3DSA:2.120.10.30 28 271 8.5E-10 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CU254_RS27850 4879c59793f5aab9bc2b8b8c9a1b7df9 127 Pfam PF03795 YCII-related domain 2 116 1.7E-16 T 28-03-2018 IPR005545 YCII-related CU254_RS27850 4879c59793f5aab9bc2b8b8c9a1b7df9 127 Gene3D G3DSA:3.30.70.1060 1 120 5.3E-39 T 28-03-2018 CU254_RS27850 4879c59793f5aab9bc2b8b8c9a1b7df9 127 SUPERFAMILY SSF54909 2 117 6.43E-30 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS01870 25fcc6900f702e863edf6f09dcdd75b0 193 Pfam PF02575 YbaB/EbfC DNA-binding family 20 101 4.0E-10 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CU254_RS01870 25fcc6900f702e863edf6f09dcdd75b0 193 SUPERFAMILY SSF82607 16 98 1.44E-7 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CU254_RS01870 25fcc6900f702e863edf6f09dcdd75b0 193 Gene3D G3DSA:3.30.1310.10 1 111 4.2E-18 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CU254_RS36715 13ddca0b3bc113c9398d31c06953673b 146 Gene3D G3DSA:1.10.1220.10 68 92 0.14 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CU254_RS36715 13ddca0b3bc113c9398d31c06953673b 146 Gene3D G3DSA:1.10.1220.10 104 145 2.6E-7 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CU254_RS40880 55807b5036dfe6e0d5af7faa42e22dc8 109 SUPERFAMILY SSF54197 5 95 1.05E-15 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CU254_RS40880 55807b5036dfe6e0d5af7faa42e22dc8 109 Gene3D G3DSA:3.30.428.10 1 109 4.7E-15 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CU254_RS40880 55807b5036dfe6e0d5af7faa42e22dc8 109 Pfam PF01230 HIT domain 8 84 2.2E-9 T 28-03-2018 IPR001310 Histidine triad (HIT) protein CU254_RS07350 46aae4a317e1f2cb7db974cad511f531 107 SUPERFAMILY SSF46785 11 104 1.01E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS07350 46aae4a317e1f2cb7db974cad511f531 107 Pfam PF03551 Transcriptional regulator PadR-like family 15 86 6.7E-19 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CU254_RS07350 46aae4a317e1f2cb7db974cad511f531 107 Gene3D G3DSA:1.10.10.10 1 97 1.7E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS21710 2059d72797b422ecf8284de815c5fe89 116 Gene3D G3DSA:3.10.129.10 21 115 9.4E-16 T 28-03-2018 CU254_RS21710 2059d72797b422ecf8284de815c5fe89 116 Pfam PF07977 FabA-like domain 25 60 5.3E-6 T 28-03-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CU254_RS21710 2059d72797b422ecf8284de815c5fe89 116 SUPERFAMILY SSF54637 23 112 4.56E-13 T 28-03-2018 IPR029069 HotDog domain CU254_RS36160 11c12bda254a165bc4387b0685b52988 102 Gene3D G3DSA:3.30.70.100 1 102 8.6E-30 T 28-03-2018 CU254_RS36160 11c12bda254a165bc4387b0685b52988 102 SUPERFAMILY SSF54909 1 96 4.03E-24 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS36160 11c12bda254a165bc4387b0685b52988 102 Pfam PF03992 Antibiotic biosynthesis monooxygenase 3 74 1.7E-18 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain CU254_RS13170 3ae341abd28880dcd38f40ff06acd121 344 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 225 314 1.6E-20 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CU254_RS13170 3ae341abd28880dcd38f40ff06acd121 344 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 7 182 2.8E-43 T 28-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CU254_RS13170 3ae341abd28880dcd38f40ff06acd121 344 SUPERFAMILY SSF90002 225 314 2.35E-15 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CU254_RS13170 3ae341abd28880dcd38f40ff06acd121 344 Gene3D G3DSA:3.40.50.300 3 198 2.1E-37 T 28-03-2018 CU254_RS13170 3ae341abd28880dcd38f40ff06acd121 344 Gene3D G3DSA:3.30.1220.10 205 315 1.4E-22 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CU254_RS13170 3ae341abd28880dcd38f40ff06acd121 344 SMART SM00833 224 314 2.7E-17 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CU254_RS13170 3ae341abd28880dcd38f40ff06acd121 344 SUPERFAMILY SSF52540 5 212 2.14E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS00615 7dbdf4c96db3d68dd6f96014f1e842b7 402 Gene3D G3DSA:2.40.440.10 245 372 2.8E-21 T 28-03-2018 CU254_RS00615 7dbdf4c96db3d68dd6f96014f1e842b7 402 Pfam PF03734 L,D-transpeptidase catalytic domain 254 370 4.9E-15 T 28-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CU254_RS00615 7dbdf4c96db3d68dd6f96014f1e842b7 402 SUPERFAMILY SSF141523 251 370 9.42E-24 T 28-03-2018 CU254_RS29130 343411737a19d94d703e39a5b7482d5d 301 SUPERFAMILY SSF56281 40 287 1.27E-40 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS29130 343411737a19d94d703e39a5b7482d5d 301 SMART SM00849 59 273 2.5E-24 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS29130 343411737a19d94d703e39a5b7482d5d 301 Pfam PF00753 Metallo-beta-lactamase superfamily 61 273 1.4E-33 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS29130 343411737a19d94d703e39a5b7482d5d 301 Gene3D G3DSA:3.60.15.10 4 285 1.5E-50 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS35260 4cc26bbe85402c0020b30f9b2b0eada0 746 Pfam PF13625 Helicase conserved C-terminal domain 463 585 6.6E-43 T 28-03-2018 IPR032830 Helicase XPB/Ssl2, N-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 CU254_RS32975 113dd110f2d9fbfeba5ee115cb3daeb6 283 Pfam PF15575 Immunity protein 49 57 273 1.2E-49 T 28-03-2018 IPR029074 Immunity protein 49 CU254_RS19720 dca7d5747ccd6b99827c419c12146cc2 318 Gene3D G3DSA:1.10.3720.10 1 302 1.8E-44 T 28-03-2018 CU254_RS19720 dca7d5747ccd6b99827c419c12146cc2 318 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 313 7.4E-35 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS19720 dca7d5747ccd6b99827c419c12146cc2 318 SUPERFAMILY SSF161098 94 299 1.09E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS04195 40ec807e97a4b381568ce4caf8cbdbb1 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 109 289 3.2E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS04195 40ec807e97a4b381568ce4caf8cbdbb1 296 Gene3D G3DSA:1.10.3720.10 18 283 1.2E-48 T 28-03-2018 CU254_RS04195 40ec807e97a4b381568ce4caf8cbdbb1 296 SUPERFAMILY SSF161098 26 296 6.45E-73 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS37510 ffd197941e6ff68cf003a8602c17eeed 251 Pfam PF01636 Phosphotransferase enzyme family 29 172 7.1E-16 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CU254_RS37510 ffd197941e6ff68cf003a8602c17eeed 251 SUPERFAMILY SSF56112 13 207 4.18E-27 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS37510 ffd197941e6ff68cf003a8602c17eeed 251 Gene3D G3DSA:1.10.510.10 28 216 2.5E-19 T 28-03-2018 CU254_RS22170 179c9aa0874b653b563aeb5c18707dd2 484 Gene3D G3DSA:3.40.605.10 2 246 9.7E-40 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CU254_RS22170 179c9aa0874b653b563aeb5c18707dd2 484 Pfam PF00171 Aldehyde dehydrogenase family 4 392 1.0E-39 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CU254_RS22170 179c9aa0874b653b563aeb5c18707dd2 484 SUPERFAMILY SSF53720 5 479 1.83E-86 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CU254_RS22170 179c9aa0874b653b563aeb5c18707dd2 484 Gene3D G3DSA:3.40.309.10 247 417 5.8E-22 T 28-03-2018 CU254_RS06490 e3f7dd18796fecb77e837e031842751a 181 Gene3D G3DSA:2.60.120.10 23 166 6.3E-24 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS06490 e3f7dd18796fecb77e837e031842751a 181 Pfam PF05995 Cysteine dioxygenase type I 51 162 2.7E-18 T 28-03-2018 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|Reactome: R-HSA-1614558 CU254_RS06490 e3f7dd18796fecb77e837e031842751a 181 SUPERFAMILY SSF51182 27 162 6.31E-29 T 28-03-2018 IPR011051 RmlC-like cupin domain CU254_RS25100 b628cb8012f75e9f1b43cf6a03f8cf40 408 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 104 271 1.8E-43 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CU254_RS25100 b628cb8012f75e9f1b43cf6a03f8cf40 408 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 103 271 9.2E-36 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CU254_RS38150 fe8c7b62b91a4dd7c6562457699465a3 211 SUPERFAMILY SSF52540 17 205 1.76E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS38150 fe8c7b62b91a4dd7c6562457699465a3 211 Gene3D G3DSA:3.40.50.300 17 210 5.0E-34 T 28-03-2018 CU254_RS22955 3dc6cb2082e753eab5e333242b684351 456 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 264 439 2.1E-39 T 28-03-2018 IPR000160 GGDEF domain CU254_RS22955 3dc6cb2082e753eab5e333242b684351 456 Gene3D G3DSA:3.30.70.270 258 443 3.4E-50 T 28-03-2018 CU254_RS22955 3dc6cb2082e753eab5e333242b684351 456 SMART SM00267 254 440 3.5E-47 T 28-03-2018 IPR000160 GGDEF domain CU254_RS22955 3dc6cb2082e753eab5e333242b684351 456 SUPERFAMILY SSF55073 270 439 6.83E-42 T 28-03-2018 IPR029787 Nucleotide cyclase CU254_RS22955 3dc6cb2082e753eab5e333242b684351 456 Pfam PF00990 Diguanylate cyclase, GGDEF domain 265 436 2.0E-39 T 28-03-2018 IPR000160 GGDEF domain CU254_RS28385 607db3626279529539a6e1d977482b25 84 Gene3D G3DSA:1.10.10.10 2 78 0.0016 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS00385 9ef5ca7bc6d4850cb7bb347f6525efd5 285 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 172 263 8.7E-19 T 28-03-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 CU254_RS00385 9ef5ca7bc6d4850cb7bb347f6525efd5 285 Gene3D G3DSA:3.60.130.10 126 277 2.5E-23 T 28-03-2018 CU254_RS00385 9ef5ca7bc6d4850cb7bb347f6525efd5 285 SUPERFAMILY SSF51197 166 269 3.48E-27 T 28-03-2018 CU254_RS28075 52d6798a367cd1ee102f4e34464d53ec 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 3.6E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS28075 52d6798a367cd1ee102f4e34464d53ec 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 3.6E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS28075 52d6798a367cd1ee102f4e34464d53ec 209 SUPERFAMILY SSF46689 7 79 8.72E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS28075 52d6798a367cd1ee102f4e34464d53ec 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 67 5.5E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS28075 52d6798a367cd1ee102f4e34464d53ec 209 Gene3D G3DSA:1.10.357.10 5 209 3.9E-32 T 28-03-2018 CU254_RS18000 dc365f8661181319749896f178aedad1 184 Gene3D G3DSA:3.90.550.10 4 177 5.3E-24 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS18000 dc365f8661181319749896f178aedad1 184 SUPERFAMILY SSF53448 5 181 1.49E-26 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS18000 dc365f8661181319749896f178aedad1 184 Pfam PF12804 MobA-like NTP transferase domain 8 155 2.8E-25 T 28-03-2018 IPR025877 MobA-like NTP transferase CU254_RS02705 19186ee9a18c460fb55a675dd1d9fe05 137 Gene3D G3DSA:3.40.1490.10 6 135 2.5E-44 T 28-03-2018 IPR023476 Peptidyl-tRNA hydrolase II domain MetaCyc: PWY-6308 CU254_RS02705 19186ee9a18c460fb55a675dd1d9fe05 137 Pfam PF09391 Protein of unknown function (DUF2000) 6 136 2.0E-41 T 28-03-2018 IPR018988 Protein of unknown function DUF2000 CU254_RS02705 19186ee9a18c460fb55a675dd1d9fe05 137 SUPERFAMILY SSF102462 3 136 1.57E-43 T 28-03-2018 IPR023476 Peptidyl-tRNA hydrolase II domain MetaCyc: PWY-6308 CU254_RS08285 d9ff042d3a51f00726784c0e66978ee1 197 SUPERFAMILY SSF52218 6 154 3.86E-36 T 28-03-2018 IPR029039 Flavoprotein-like domain CU254_RS08285 d9ff042d3a51f00726784c0e66978ee1 197 Gene3D G3DSA:3.40.50.360 5 190 7.5E-34 T 28-03-2018 IPR029039 Flavoprotein-like domain CU254_RS08285 d9ff042d3a51f00726784c0e66978ee1 197 Pfam PF03358 NADPH-dependent FMN reductase 6 150 1.1E-34 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CU254_RS11765 e2c5de242fc0898b6a73c21a0a88da9a 287 SUPERFAMILY SSF56059 78 259 1.84E-13 T 28-03-2018 CU254_RS11765 e2c5de242fc0898b6a73c21a0a88da9a 287 Gene3D G3DSA:3.30.1490.20 110 153 1.6E-4 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CU254_RS11765 e2c5de242fc0898b6a73c21a0a88da9a 287 Gene3D G3DSA:3.30.470.20 154 274 2.2E-9 T 28-03-2018 CU254_RS38465 29fabea378f099d113b8fd1643dde113 562 Pfam PF00149 Calcineurin-like phosphoesterase 34 283 4.2E-9 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CU254_RS38465 29fabea378f099d113b8fd1643dde113 562 Gene3D G3DSA:3.60.21.10 22 362 1.6E-73 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CU254_RS38465 29fabea378f099d113b8fd1643dde113 562 Pfam PF02872 5'-nucleotidase, C-terminal domain 364 525 5.1E-40 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CU254_RS38465 29fabea378f099d113b8fd1643dde113 562 SUPERFAMILY SSF56300 27 361 3.07E-66 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CU254_RS38465 29fabea378f099d113b8fd1643dde113 562 Gene3D G3DSA:3.90.780.10 363 561 2.5E-53 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CU254_RS38465 29fabea378f099d113b8fd1643dde113 562 PRINTS PR01607 Apyrase family signature 499 518 2.3E-20 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CU254_RS38465 29fabea378f099d113b8fd1643dde113 562 PRINTS PR01607 Apyrase family signature 297 317 2.3E-20 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CU254_RS38465 29fabea378f099d113b8fd1643dde113 562 PRINTS PR01607 Apyrase family signature 427 450 2.3E-20 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CU254_RS38465 29fabea378f099d113b8fd1643dde113 562 PRINTS PR01607 Apyrase family signature 31 49 2.3E-20 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CU254_RS38465 29fabea378f099d113b8fd1643dde113 562 PRINTS PR01607 Apyrase family signature 266 289 2.3E-20 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CU254_RS38465 29fabea378f099d113b8fd1643dde113 562 SUPERFAMILY SSF55816 361 560 1.44E-51 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CU254_RS38780 23c91d18191a23514062056a441e0326 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 151 207 3.7E-21 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS38780 23c91d18191a23514062056a441e0326 218 Gene3D G3DSA:1.10.10.10 126 216 5.9E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS38780 23c91d18191a23514062056a441e0326 218 SMART SM00448 2 114 1.1E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS38780 23c91d18191a23514062056a441e0326 218 Gene3D G3DSA:3.40.50.2300 1 125 5.8E-36 T 28-03-2018 CU254_RS38780 23c91d18191a23514062056a441e0326 218 ProSitePatterns PS00622 LuxR-type HTH domain signature. 167 194 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS38780 23c91d18191a23514062056a441e0326 218 SUPERFAMILY SSF46894 144 213 1.09E-23 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS38780 23c91d18191a23514062056a441e0326 218 SUPERFAMILY SSF52172 2 134 1.35E-31 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS38780 23c91d18191a23514062056a441e0326 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 3.9E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS38780 23c91d18191a23514062056a441e0326 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 3.9E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS38780 23c91d18191a23514062056a441e0326 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 3.9E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS38780 23c91d18191a23514062056a441e0326 218 SMART SM00421 150 207 6.7E-28 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS38780 23c91d18191a23514062056a441e0326 218 Pfam PF00072 Response regulator receiver domain 4 114 3.4E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS28905 329c1c971ec72767ee3d3b81d40234d2 213 Pfam PF12079 Protein of unknown function (DUF3558) 27 194 5.4E-19 T 28-03-2018 IPR024520 Protein of unknown function DUF3558 CU254_RS01585 f9d01b1f9d53f669ad72cf6c0a8ff85b 262 Gene3D G3DSA:3.90.550.10 1 256 6.3E-33 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS01585 f9d01b1f9d53f669ad72cf6c0a8ff85b 262 SUPERFAMILY SSF53448 1 255 8.79E-42 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS08300 c946c454c9353b47dc09151d336fa773 84 Pfam PF10939 Protein of unknown function (DUF2631) 2 65 8.8E-30 T 28-03-2018 IPR024341 Protein of unknown function DUF2631 CU254_RS08300 c946c454c9353b47dc09151d336fa773 84 ProDom PD069408 TRANSMEMBRANE MEMBRANE RV2876/MT2944.1 CGL2017/CG2211 ML1584 POSSIBLE P20 11 59 3.0E-8 T 28-03-2018 IPR024341 Protein of unknown function DUF2631 CU254_RS19350 bb0f3329a1770579e2aed97d96de05e5 525 Pfam PF02515 CoA-transferase family III 81 251 8.9E-7 T 28-03-2018 IPR003673 CoA-transferase family III GO:0003824 CU254_RS19350 bb0f3329a1770579e2aed97d96de05e5 525 Pfam PF02515 CoA-transferase family III 281 476 4.9E-43 T 28-03-2018 IPR003673 CoA-transferase family III GO:0003824 CU254_RS19350 bb0f3329a1770579e2aed97d96de05e5 525 SUPERFAMILY SSF89796 279 478 5.89E-49 T 28-03-2018 IPR023606 CoA-transferase family III domain CU254_RS19350 bb0f3329a1770579e2aed97d96de05e5 525 Gene3D G3DSA:3.40.50.10540 63 257 1.4E-15 T 28-03-2018 IPR023606 CoA-transferase family III domain CU254_RS19350 bb0f3329a1770579e2aed97d96de05e5 525 Gene3D G3DSA:3.40.50.10540 275 502 3.6E-54 T 28-03-2018 IPR023606 CoA-transferase family III domain CU254_RS19350 bb0f3329a1770579e2aed97d96de05e5 525 SUPERFAMILY SSF89796 77 273 3.53E-15 T 28-03-2018 IPR023606 CoA-transferase family III domain CU254_RS14490 c309107dae625f67a33cc592d61ad9f8 243 SUPERFAMILY SSF52096 5 238 1.44E-68 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS14490 c309107dae625f67a33cc592d61ad9f8 243 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 104 124 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CU254_RS14490 c309107dae625f67a33cc592d61ad9f8 243 Pfam PF00378 Enoyl-CoA hydratase/isomerase 12 229 4.6E-49 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CU254_RS14490 c309107dae625f67a33cc592d61ad9f8 243 Gene3D G3DSA:3.90.226.10 2 241 1.3E-65 T 28-03-2018 CU254_RS15260 ff2f8d0847dbdf0cee1d6a06ddac9c8a 293 SUPERFAMILY SSF53474 212 289 2.61E-50 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS15260 ff2f8d0847dbdf0cee1d6a06ddac9c8a 293 SUPERFAMILY SSF53474 3 140 2.61E-50 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS15260 ff2f8d0847dbdf0cee1d6a06ddac9c8a 293 Gene3D G3DSA:3.40.50.1820 1 291 9.7E-42 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS15260 ff2f8d0847dbdf0cee1d6a06ddac9c8a 293 Pfam PF12146 Serine aminopeptidase, S33 26 263 4.6E-12 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 CU254_RS18945 c45d8c165d1888d1d65dc838ebbbf38b 539 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 78 467 1.1E-74 T 28-03-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 CU254_RS18945 c45d8c165d1888d1d65dc838ebbbf38b 539 SUPERFAMILY SSF56317 236 502 1.83E-38 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CU254_RS18945 c45d8c165d1888d1d65dc838ebbbf38b 539 Pfam PF00795 Carbon-nitrogen hydrolase 283 486 1.2E-20 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CU254_RS18945 c45d8c165d1888d1d65dc838ebbbf38b 539 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 25 505 16.451 T 28-03-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 CU254_RS18945 c45d8c165d1888d1d65dc838ebbbf38b 539 Gene3D G3DSA:3.60.110.10 226 502 1.4E-38 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CU254_RS03710 12b250004e883a38ba62e96daf26bee3 109 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 49 77 2.4E-11 T 28-03-2018 IPR019933 DivIVA domain CU254_RS22540 a5419c9540ef27f58461baaeb0c04a53 432 SUPERFAMILY SSF51419 58 274 1.26E-24 T 28-03-2018 IPR029066 PLP-binding barrel CU254_RS22540 a5419c9540ef27f58461baaeb0c04a53 432 Pfam PF01168 Alanine racemase, N-terminal domain 58 252 1.5E-10 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CU254_RS22540 a5419c9540ef27f58461baaeb0c04a53 432 Pfam PF14031 Putative serine dehydratase domain 322 417 3.7E-15 T 28-03-2018 IPR026956 D-serine dehydratase-like domain CU254_RS22540 a5419c9540ef27f58461baaeb0c04a53 432 SMART SM01119 322 418 4.1E-36 T 28-03-2018 IPR026956 D-serine dehydratase-like domain CU254_RS22540 a5419c9540ef27f58461baaeb0c04a53 432 Gene3D G3DSA:3.20.20.10 52 306 2.6E-36 T 28-03-2018 IPR029066 PLP-binding barrel CU254_RS00030 7be62c00e715841479e785bee6c2985b 148 Gene3D G3DSA:3.30.530.20 1 148 8.6E-16 T 28-03-2018 IPR023393 START-like domain CU254_RS00030 7be62c00e715841479e785bee6c2985b 148 SUPERFAMILY SSF55961 6 135 5.08E-13 T 28-03-2018 CU254_RS00030 7be62c00e715841479e785bee6c2985b 148 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 7 142 1.9E-16 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase CU254_RS36595 6e191eaf59b8da179d8b92e2e77089fb 291 Pfam PF00248 Aldo/keto reductase family 20 290 1.3E-49 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS36595 6e191eaf59b8da179d8b92e2e77089fb 291 PRINTS PR00069 Aldo-keto reductase signature 45 69 5.0E-8 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CU254_RS36595 6e191eaf59b8da179d8b92e2e77089fb 291 PRINTS PR00069 Aldo-keto reductase signature 150 167 5.0E-8 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CU254_RS36595 6e191eaf59b8da179d8b92e2e77089fb 291 PRINTS PR00069 Aldo-keto reductase signature 224 248 5.0E-8 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CU254_RS36595 6e191eaf59b8da179d8b92e2e77089fb 291 SUPERFAMILY SSF51430 15 290 4.85E-63 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS36595 6e191eaf59b8da179d8b92e2e77089fb 291 Gene3D G3DSA:3.20.20.100 10 291 1.7E-64 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS16860 ed114f8028491c0d6e943b3f1fe5d177 328 Gene3D G3DSA:3.40.109.10 109 318 6.3E-17 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CU254_RS16860 ed114f8028491c0d6e943b3f1fe5d177 328 Gene3D G3DSA:3.40.109.30 8 93 0.11 T 28-03-2018 CU254_RS25275 1bd0f67f8a9ee1173b8de1a3556afb0b 331 Pfam PF04657 Putative inner membrane exporter, YdcZ 16 159 2.2E-23 T 28-03-2018 IPR006750 Putative inner membrane exporter, YdcZ CU254_RS25275 1bd0f67f8a9ee1173b8de1a3556afb0b 331 Pfam PF04657 Putative inner membrane exporter, YdcZ 174 307 3.0E-12 T 28-03-2018 IPR006750 Putative inner membrane exporter, YdcZ CU254_RS39270 a7163805d3f8043e80b664c2dee93d38 218 Pfam PF12089 Transmembrane domain of unknown function (DUF3566) 98 216 1.6E-43 T 28-03-2018 IPR021949 Domain of unknown function DUF3566. transmembrane CU254_RS36465 26d699f9e2355265d0532cbae4c0798a 283 Pfam PF14011 EspG family 74 270 7.3E-9 T 28-03-2018 IPR025734 EspG family CU254_RS11210 3146903467620d89cf61308abfacbdb0 128 Pfam PF03780 Asp23 family, cell envelope-related function 20 117 5.9E-13 T 28-03-2018 IPR005531 Alkaline shock protein Asp23 CU254_RS00855 7ce97971c8b9e388dbd94052700b0ea2 388 SUPERFAMILY SSF53383 7 387 5.98E-105 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS00855 7ce97971c8b9e388dbd94052700b0ea2 388 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 197 220 6.0E-11 T 28-03-2018 CU254_RS00855 7ce97971c8b9e388dbd94052700b0ea2 388 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 112 133 6.0E-11 T 28-03-2018 CU254_RS00855 7ce97971c8b9e388dbd94052700b0ea2 388 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 90 110 6.0E-11 T 28-03-2018 CU254_RS00855 7ce97971c8b9e388dbd94052700b0ea2 388 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 161 185 6.0E-11 T 28-03-2018 CU254_RS00855 7ce97971c8b9e388dbd94052700b0ea2 388 Pfam PF00155 Aminotransferase class I and II 30 384 1.1E-64 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CU254_RS00855 7ce97971c8b9e388dbd94052700b0ea2 388 Gene3D G3DSA:3.90.1150.10 295 388 4.6E-20 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS00855 7ce97971c8b9e388dbd94052700b0ea2 388 Gene3D G3DSA:3.40.640.10 45 294 8.7E-64 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS00505 6cb454c90bccdf79509eaa2f1bd8c61d 520 SUPERFAMILY SSF52540 245 496 9.3E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS00505 6cb454c90bccdf79509eaa2f1bd8c61d 520 Gene3D G3DSA:3.40.50.300 274 448 5.0E-4 T 28-03-2018 CU254_RS00505 6cb454c90bccdf79509eaa2f1bd8c61d 520 Pfam PF01580 FtsK/SpoIIIE family 276 445 4.9E-8 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CU254_RS00280 479f1e95593f94058f87af78e7b3a39a 246 SMART SM00547 5 29 0.0063 T 28-03-2018 IPR001876 Zinc finger, RanBP2-type CU254_RS00280 479f1e95593f94058f87af78e7b3a39a 246 Gene3D G3DSA:4.10.1060.10 1 64 1.1E-7 T 28-03-2018 CU254_RS00280 479f1e95593f94058f87af78e7b3a39a 246 ProSitePatterns PS01358 Zinc finger RanBP2-type signature. 7 26 - T 28-03-2018 IPR001876 Zinc finger, RanBP2-type CU254_RS27165 2db51a6d9871fa8edc9be75faad05d33 409 Gene3D G3DSA:3.40.720.10 24 409 2.8E-106 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CU254_RS27165 2db51a6d9871fa8edc9be75faad05d33 409 SMART SM00098 40 409 1.5E-53 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CU254_RS27165 2db51a6d9871fa8edc9be75faad05d33 409 Pfam PF00245 Alkaline phosphatase 39 339 8.8E-72 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CU254_RS27165 2db51a6d9871fa8edc9be75faad05d33 409 SUPERFAMILY SSF53649 36 408 5.89E-103 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CU254_RS27165 2db51a6d9871fa8edc9be75faad05d33 409 ProSitePatterns PS00123 Alkaline phosphatase active site. 91 99 - T 28-03-2018 IPR018299 Alkaline phosphatase, active site GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CU254_RS27165 2db51a6d9871fa8edc9be75faad05d33 409 PRINTS PR00113 Alkaline phosphatase signature 91 106 2.1E-33 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CU254_RS27165 2db51a6d9871fa8edc9be75faad05d33 409 PRINTS PR00113 Alkaline phosphatase signature 260 289 2.1E-33 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CU254_RS27165 2db51a6d9871fa8edc9be75faad05d33 409 PRINTS PR00113 Alkaline phosphatase signature 128 148 2.1E-33 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CU254_RS27165 2db51a6d9871fa8edc9be75faad05d33 409 PRINTS PR00113 Alkaline phosphatase signature 39 59 2.1E-33 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CU254_RS27165 2db51a6d9871fa8edc9be75faad05d33 409 PRINTS PR00113 Alkaline phosphatase signature 173 183 2.1E-33 T 28-03-2018 IPR001952 Alkaline phosphatase GO:0008152|GO:0016791 KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 CU254_RS17180 924899942d600739f8d29202dbea4169 423 Gene3D G3DSA:1.10.606.10 162 422 6.5E-58 T 28-03-2018 IPR016119 Bromoperoxidase/chloroperoxidase, C-terminal GO:0004601|GO:0055114 CU254_RS17180 924899942d600739f8d29202dbea4169 423 Pfam PF01569 PAP2 superfamily 294 423 3.9E-7 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CU254_RS17180 924899942d600739f8d29202dbea4169 423 Gene3D G3DSA:1.20.144.10 27 161 2.7E-5 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CU254_RS17180 924899942d600739f8d29202dbea4169 423 SUPERFAMILY SSF48317 39 421 4.32E-62 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CU254_RS05155 19467ff3136d1d1f4f48554538d25741 251 Gene3D G3DSA:3.40.50.150 39 251 2.8E-12 T 28-03-2018 CU254_RS05155 19467ff3136d1d1f4f48554538d25741 251 Pfam PF08241 Methyltransferase domain 55 139 5.6E-5 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CU254_RS05155 19467ff3136d1d1f4f48554538d25741 251 SUPERFAMILY SSF53335 20 250 6.17E-16 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS33365 690b092fe051eb2c1ce7ff316bbe0eea 530 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 85 435 4.4E-52 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CU254_RS33365 690b092fe051eb2c1ce7ff316bbe0eea 530 Gene3D G3DSA:3.40.190.10 159 294 3.1E-17 T 28-03-2018 CU254_RS33365 690b092fe051eb2c1ce7ff316bbe0eea 530 Gene3D G3DSA:3.10.105.10 295 500 2.4E-30 T 28-03-2018 CU254_RS33365 690b092fe051eb2c1ce7ff316bbe0eea 530 PIRSF PIRSF002741 2 516 9.0E-55 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CU254_RS33365 690b092fe051eb2c1ce7ff316bbe0eea 530 Gene3D G3DSA:3.90.76.10 67 158 3.6E-18 T 28-03-2018 CU254_RS33365 690b092fe051eb2c1ce7ff316bbe0eea 530 SUPERFAMILY SSF53850 38 499 3.26E-80 T 28-03-2018 CU254_RS40345 9421396c4d9c5c8540ab395f12b12fb7 417 Gene3D G3DSA:1.10.287.1060 36 118 4.8E-4 T 28-03-2018 CU254_RS00145 fee9700a2a4af02e5fc3803dc98d7e8f 121 Gene3D G3DSA:1.10.10.10 8 116 1.0E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS00145 fee9700a2a4af02e5fc3803dc98d7e8f 121 Pfam PF05331 Protein of unknown function (DUF742) 11 120 8.6E-35 T 28-03-2018 IPR007995 Protein of unknown function DUF742 CU254_RS06250 ad65fbac0c7a761eb2066293cae71b31 329 SUPERFAMILY SSF51735 5 139 1.24E-19 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS06250 ad65fbac0c7a761eb2066293cae71b31 329 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 7 124 1.3E-18 T 28-03-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 CU254_RS06250 ad65fbac0c7a761eb2066293cae71b31 329 Gene3D G3DSA:3.40.50.720 1 120 2.0E-21 T 28-03-2018 CU254_RS01545 fd60d9b33d3d95b05817dedad3be29df 273 SUPERFAMILY SSF51126 49 260 1.09E-13 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor CU254_RS01545 fd60d9b33d3d95b05817dedad3be29df 273 Gene3D G3DSA:2.160.20.10 30 271 5.7E-17 T 28-03-2018 IPR012334 Pectin lyase fold CU254_RS00805 90192918f3a99c9a56f71d26a84d1b37 458 Gene3D G3DSA:3.90.1300.10 3 456 4.6E-124 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS00805 90192918f3a99c9a56f71d26a84d1b37 458 SUPERFAMILY SSF75304 10 446 1.44E-114 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS00805 90192918f3a99c9a56f71d26a84d1b37 458 Pfam PF01425 Amidase 28 436 1.1E-100 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS00805 90192918f3a99c9a56f71d26a84d1b37 458 ProSitePatterns PS00571 Amidases signature. 153 184 - T 28-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CU254_RS32980 217ebe238172ac45cb21775742cc6a6c 678 SUPERFAMILY SSF160424 544 673 1.83E-15 T 28-03-2018 IPR006728 Protein of unknown function DUF600 CU254_RS32980 217ebe238172ac45cb21775742cc6a6c 678 SUPERFAMILY SSF160424 12 142 8.5E-15 T 28-03-2018 IPR006728 Protein of unknown function DUF600 CU254_RS35570 1ca2d1e3307bdeec45e2796d1f9057da 227 Pfam PF11361 Protein of unknown function (DUF3159) 18 203 3.2E-53 T 28-03-2018 IPR016566 Uncharacterised conserved protein UCP010219 CU254_RS14225 adaf494a67ab2b47aeb42acfd77cdfdc 535 Gene3D G3DSA:3.40.50.10140 306 429 1.8E-5 T 28-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 CU254_RS14225 adaf494a67ab2b47aeb42acfd77cdfdc 535 Gene3D G3DSA:3.40.50.300 2 256 3.6E-33 T 28-03-2018 CU254_RS14225 adaf494a67ab2b47aeb42acfd77cdfdc 535 Pfam PF13614 AAA domain 5 183 4.6E-9 T 28-03-2018 IPR025669 AAA domain CU254_RS14225 adaf494a67ab2b47aeb42acfd77cdfdc 535 SUPERFAMILY SSF52540 5 222 1.01E-27 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS34560 45c4a3b5031583dea6dcfd60ddbecacc 134 SUPERFAMILY SSF50475 27 131 4.58E-8 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS34560 45c4a3b5031583dea6dcfd60ddbecacc 134 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 21 133 9.9E-34 T 28-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CU254_RS34560 45c4a3b5031583dea6dcfd60ddbecacc 134 Pfam PF04075 F420H(2)-dependent quinone reductase 10 133 2.2E-41 T 28-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CU254_RS34560 45c4a3b5031583dea6dcfd60ddbecacc 134 Gene3D G3DSA:2.30.110.10 1 134 2.9E-46 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS33055 7e398abaefd97bf152fdf5a3188da187 238 Gene3D G3DSA:2.40.260.10 36 238 1.4E-16 T 28-03-2018 IPR023365 Sortase domain CU254_RS33055 7e398abaefd97bf152fdf5a3188da187 238 SUPERFAMILY SSF63817 92 225 1.26E-11 T 28-03-2018 IPR023365 Sortase domain CU254_RS33055 7e398abaefd97bf152fdf5a3188da187 238 Pfam PF04203 Sortase family 137 235 1.4E-6 T 28-03-2018 IPR005754 Sortase family CU254_RS36050 bd4157136ef18145297e234806605130 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 2.7E-5 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CU254_RS36050 bd4157136ef18145297e234806605130 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 147 167 2.7E-5 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CU254_RS36050 bd4157136ef18145297e234806605130 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 129 145 2.7E-5 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CU254_RS36050 bd4157136ef18145297e234806605130 227 Gene3D G3DSA:3.40.50.1000 77 220 3.5E-26 T 28-03-2018 IPR023214 HAD-like domain CU254_RS36050 bd4157136ef18145297e234806605130 227 Gene3D G3DSA:3.40.50.1000 1 27 0.15 T 28-03-2018 IPR023214 HAD-like domain CU254_RS36050 bd4157136ef18145297e234806605130 227 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 58 184 1.3E-15 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CU254_RS36050 bd4157136ef18145297e234806605130 227 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 184 1.9E-22 T 28-03-2018 IPR023214 HAD-like domain CU254_RS36050 bd4157136ef18145297e234806605130 227 Gene3D G3DSA:1.10.150.240 28 76 9.3E-19 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CU254_RS36050 bd4157136ef18145297e234806605130 227 SUPERFAMILY SSF56784 1 210 1.42E-45 T 28-03-2018 IPR023214 HAD-like domain CU254_RS41520 9e81e35c21020339292958d74de44242 348 Gene3D G3DSA:3.40.50.300 61 335 8.6E-32 T 28-03-2018 CU254_RS41520 9e81e35c21020339292958d74de44242 348 SUPERFAMILY SSF52540 63 334 4.62E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS41520 9e81e35c21020339292958d74de44242 348 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 63 310 5.6E-12 T 28-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CU254_RS14380 6ee104100ba524af7d5b0c2cf013b260 202 Pfam PF17197 Domain of unknown function (DUF5134) 34 201 1.4E-27 T 28-03-2018 IPR033458 Protein of unknown function DUF5134 CU254_RS14380 6ee104100ba524af7d5b0c2cf013b260 202 ProDom PD338207 MEMBRANE INTEGRAL TRANSMEMBRANE PLASMID PROBABLE MB0995 RV0970/MT0998 1 64 9.0E-10 T 28-03-2018 CU254_RS34890 2527be58f493a9229b9043526ebb6106 187 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 2.1E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS34890 2527be58f493a9229b9043526ebb6106 187 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 2.1E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS34890 2527be58f493a9229b9043526ebb6106 187 SUPERFAMILY SSF46689 2 80 5.34E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS34890 2527be58f493a9229b9043526ebb6106 187 Gene3D G3DSA:1.10.10.60 7 61 1.0E-17 T 28-03-2018 CU254_RS34890 2527be58f493a9229b9043526ebb6106 187 Gene3D G3DSA:1.10.357.10 62 187 9.4E-20 T 28-03-2018 CU254_RS34890 2527be58f493a9229b9043526ebb6106 187 ProSitePatterns PS01081 TetR-type HTH domain signature. 24 55 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CU254_RS34890 2527be58f493a9229b9043526ebb6106 187 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 57 7.7E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS03840 f2b1f9480578294f89cee828cc599b4d 315 Gene3D G3DSA:1.10.3720.10 33 303 1.8E-50 T 28-03-2018 CU254_RS03840 f2b1f9480578294f89cee828cc599b4d 315 SUPERFAMILY SSF161098 29 303 3.53E-49 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS03840 f2b1f9480578294f89cee828cc599b4d 315 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 302 5.9E-12 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS04070 516035e6cffbb369c35286832178a1ea 268 Gene3D G3DSA:3.40.50.10090 38 165 1.0E-16 T 28-03-2018 CU254_RS04070 516035e6cffbb369c35286832178a1ea 268 Pfam PF02602 Uroporphyrinogen-III synthase HemD 19 260 1.3E-33 T 28-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CU254_RS04070 516035e6cffbb369c35286832178a1ea 268 SUPERFAMILY SSF69618 6 265 3.27E-49 T 28-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CU254_RS04070 516035e6cffbb369c35286832178a1ea 268 Gene3D G3DSA:3.40.50.10090 166 267 6.9E-15 T 28-03-2018 CU254_RS39045 67b5d1d6b677c40feff76228be046adf 289 PRINTS PR00990 Ribokinase signature 170 185 2.3E-30 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CU254_RS39045 67b5d1d6b677c40feff76228be046adf 289 PRINTS PR00990 Ribokinase signature 33 52 2.3E-30 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CU254_RS39045 67b5d1d6b677c40feff76228be046adf 289 PRINTS PR00990 Ribokinase signature 207 218 2.3E-30 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CU254_RS39045 67b5d1d6b677c40feff76228be046adf 289 PRINTS PR00990 Ribokinase signature 104 117 2.3E-30 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CU254_RS39045 67b5d1d6b677c40feff76228be046adf 289 PRINTS PR00990 Ribokinase signature 6 27 2.3E-30 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CU254_RS39045 67b5d1d6b677c40feff76228be046adf 289 SUPERFAMILY SSF53613 2 286 6.08E-83 T 28-03-2018 IPR029056 Ribokinase-like CU254_RS39045 67b5d1d6b677c40feff76228be046adf 289 Hamap MF_01987 Ribokinase [rbsK]. 2 289 24.401 T 28-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 CU254_RS39045 67b5d1d6b677c40feff76228be046adf 289 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 236 249 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CU254_RS39045 67b5d1d6b677c40feff76228be046adf 289 Pfam PF00294 pfkB family carbohydrate kinase 2 284 5.6E-69 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CU254_RS39045 67b5d1d6b677c40feff76228be046adf 289 Gene3D G3DSA:3.40.1190.20 2 289 3.2E-81 T 28-03-2018 IPR029056 Ribokinase-like CU254_RS37595 cdf65a2e3a8fa181a1d0fd02c20c8df8 515 SUPERFAMILY SSF53271 268 482 3.8E-67 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CU254_RS37595 cdf65a2e3a8fa181a1d0fd02c20c8df8 515 Gene3D G3DSA:3.60.20.10 27 274 4.7E-59 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CU254_RS37595 cdf65a2e3a8fa181a1d0fd02c20c8df8 515 Pfam PF13522 Glutamine amidotransferase domain 85 227 2.2E-16 T 28-03-2018 CU254_RS37595 cdf65a2e3a8fa181a1d0fd02c20c8df8 515 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 27 474 1.4E-158 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CU254_RS37595 cdf65a2e3a8fa181a1d0fd02c20c8df8 515 Gene3D G3DSA:3.40.50.2020 287 456 3.0E-31 T 28-03-2018 CU254_RS37595 cdf65a2e3a8fa181a1d0fd02c20c8df8 515 SUPERFAMILY SSF56235 27 285 2.74E-63 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CU254_RS37595 cdf65a2e3a8fa181a1d0fd02c20c8df8 515 PIRSF PIRSF000485 23 486 8.5E-159 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CU254_RS37595 cdf65a2e3a8fa181a1d0fd02c20c8df8 515 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 26 473 45.74 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CU254_RS40590 2ecd41eb7cfc55c7e3b07652fed03da5 137 Gene3D G3DSA:3.40.50.300 1 136 3.4E-10 T 28-03-2018 CU254_RS40590 2ecd41eb7cfc55c7e3b07652fed03da5 137 SUPERFAMILY SSF52540 1 135 8.47E-10 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS12270 2a48785581c0c12ef1036e7c0c4e7770 400 SUPERFAMILY SSF140459 70 232 3.66E-9 T 28-03-2018 CU254_RS12270 2a48785581c0c12ef1036e7c0c4e7770 400 Pfam PF00823 PPE family 70 218 2.7E-7 T 28-03-2018 IPR000030 PPE family CU254_RS12270 2a48785581c0c12ef1036e7c0c4e7770 400 Gene3D G3DSA:1.10.287.850 68 168 6.6E-10 T 28-03-2018 CU254_RS36535 4b9d9788a6e42510ee36adcc21fd0372 248 Pfam PF00482 Type II secretion system (T2SS), protein F 91 202 8.3E-7 T 28-03-2018 IPR018076 Type II secretion system F domain CU254_RS16985 151423219a573e19b96de5863e7b2cfb 1107 Gene3D G3DSA:1.20.90.10 996 1093 4.1E-15 T 28-03-2018 IPR016090 Phospholipase A2 domain GO:0004623|GO:0006644|GO:0050482 KEGG: 00564+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 CU254_RS16985 151423219a573e19b96de5863e7b2cfb 1107 SUPERFAMILY SSF48619 1011 1093 1.14E-10 T 28-03-2018 IPR016090 Phospholipase A2 domain GO:0004623|GO:0006644|GO:0050482 KEGG: 00564+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 CU254_RS16985 151423219a573e19b96de5863e7b2cfb 1107 Pfam PF03752 Short repeats of unknown function 716 751 2.4E-11 T 28-03-2018 IPR005506 Protein of unknown function DUF312 CU254_RS16985 151423219a573e19b96de5863e7b2cfb 1107 Pfam PF03752 Short repeats of unknown function 764 797 2.6E-7 T 28-03-2018 IPR005506 Protein of unknown function DUF312 CU254_RS16985 151423219a573e19b96de5863e7b2cfb 1107 Pfam PF03752 Short repeats of unknown function 618 658 1.6E-10 T 28-03-2018 IPR005506 Protein of unknown function DUF312 CU254_RS16985 151423219a573e19b96de5863e7b2cfb 1107 Pfam PF03752 Short repeats of unknown function 111 149 7.8E-6 T 28-03-2018 IPR005506 Protein of unknown function DUF312 CU254_RS16985 151423219a573e19b96de5863e7b2cfb 1107 Pfam PF03752 Short repeats of unknown function 63 100 6.4E-14 T 28-03-2018 IPR005506 Protein of unknown function DUF312 CU254_RS16985 151423219a573e19b96de5863e7b2cfb 1107 Pfam PF03752 Short repeats of unknown function 164 196 2.2E-7 T 28-03-2018 IPR005506 Protein of unknown function DUF312 CU254_RS16985 151423219a573e19b96de5863e7b2cfb 1107 Pfam PF03752 Short repeats of unknown function 204 243 1.0E-9 T 28-03-2018 IPR005506 Protein of unknown function DUF312 CU254_RS04410 729b6fdd0811c023b486ed2cda863b74 318 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 4 312 15.498 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CU254_RS04410 729b6fdd0811c023b486ed2cda863b74 318 Pfam PF02673 Bacitracin resistance protein BacA 10 306 4.7E-77 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CU254_RS15535 ef78de8ba677b4f91af272c846bcd753 400 SUPERFAMILY SSF51905 142 306 1.3E-33 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS15535 ef78de8ba677b4f91af272c846bcd753 400 SUPERFAMILY SSF55424 309 399 1.04E-28 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CU254_RS15535 ef78de8ba677b4f91af272c846bcd753 400 SUPERFAMILY SSF51905 4 186 3.52E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS15535 ef78de8ba677b4f91af272c846bcd753 400 Gene3D G3DSA:3.50.50.60 2 108 1.9E-17 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS15535 ef78de8ba677b4f91af272c846bcd753 400 Pfam PF14759 Reductase C-terminal 316 400 6.1E-18 T 28-03-2018 IPR028202 Reductase, C-terminal CU254_RS15535 ef78de8ba677b4f91af272c846bcd753 400 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 102 110 1.7E-10 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CU254_RS15535 ef78de8ba677b4f91af272c846bcd753 400 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 262 280 1.7E-10 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CU254_RS15535 ef78de8ba677b4f91af272c846bcd753 400 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 229 250 1.7E-10 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CU254_RS15535 ef78de8ba677b4f91af272c846bcd753 400 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 4 26 1.7E-10 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CU254_RS15535 ef78de8ba677b4f91af272c846bcd753 400 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 138 162 1.7E-10 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CU254_RS15535 ef78de8ba677b4f91af272c846bcd753 400 Gene3D G3DSA:3.50.50.60 239 317 4.2E-9 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS15535 ef78de8ba677b4f91af272c846bcd753 400 Gene3D G3DSA:3.50.50.60 109 232 5.4E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS15535 ef78de8ba677b4f91af272c846bcd753 400 Gene3D G3DSA:3.30.390.30 318 400 6.7E-32 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CU254_RS15535 ef78de8ba677b4f91af272c846bcd753 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 2.3E-26 T 28-03-2018 CU254_RS15535 ef78de8ba677b4f91af272c846bcd753 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 252 274 2.3E-26 T 28-03-2018 CU254_RS15535 ef78de8ba677b4f91af272c846bcd753 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 142 160 2.3E-26 T 28-03-2018 CU254_RS15535 ef78de8ba677b4f91af272c846bcd753 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 227 243 2.3E-26 T 28-03-2018 CU254_RS15535 ef78de8ba677b4f91af272c846bcd753 400 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 101 119 2.3E-26 T 28-03-2018 CU254_RS15535 ef78de8ba677b4f91af272c846bcd753 400 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 296 4.1E-63 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS33595 b43acc8d927d71ed3a717178fa2980f3 134 SMART SM00028 83 116 21.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS33595 b43acc8d927d71ed3a717178fa2980f3 134 SMART SM00028 49 82 0.027 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS33595 b43acc8d927d71ed3a717178fa2980f3 134 SUPERFAMILY SSF48452 22 114 2.2E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS33595 b43acc8d927d71ed3a717178fa2980f3 134 Pfam PF13432 Tetratricopeptide repeat 54 109 3.3E-7 T 28-03-2018 CU254_RS33595 b43acc8d927d71ed3a717178fa2980f3 134 Gene3D G3DSA:1.25.40.10 4 96 6.5E-16 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS33595 b43acc8d927d71ed3a717178fa2980f3 134 Gene3D G3DSA:1.25.40.10 97 129 0.0072 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS12205 50046b0eefca3b31c94288c1f274547f 352 Pfam PF00355 Rieske [2Fe-2S] domain 18 97 9.1E-17 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CU254_RS12205 50046b0eefca3b31c94288c1f274547f 352 SUPERFAMILY SSF50022 12 128 4.06E-30 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CU254_RS12205 50046b0eefca3b31c94288c1f274547f 352 Gene3D G3DSA:3.90.380.10 122 335 1.2E-30 T 28-03-2018 CU254_RS12205 50046b0eefca3b31c94288c1f274547f 352 Gene3D G3DSA:2.102.10.10 3 121 1.4E-23 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CU254_RS12205 50046b0eefca3b31c94288c1f274547f 352 SUPERFAMILY SSF55961 131 332 3.02E-33 T 28-03-2018 CU254_RS01775 d00cdda27e6c6a9543730ef3bb88dd03 443 Gene3D G3DSA:1.25.10.10 48 290 6.2E-4 T 28-03-2018 IPR011989 Armadillo-like helical CU254_RS01775 d00cdda27e6c6a9543730ef3bb88dd03 443 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 11 293 4.8E-60 T 28-03-2018 IPR005693 Virulence factor Mce protein CU254_RS01775 d00cdda27e6c6a9543730ef3bb88dd03 443 Pfam PF02470 MlaD protein 37 111 3.3E-10 T 28-03-2018 IPR003399 Mce/MlaD CU254_RS01775 d00cdda27e6c6a9543730ef3bb88dd03 443 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 143 433 2.0E-69 T 28-03-2018 IPR024516 Mammalian cell entry, C-terminal CU254_RS10655 959cde7cb43af2c5b729ac7217d74f07 265 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 254 2.8E-12 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS10655 959cde7cb43af2c5b729ac7217d74f07 265 Gene3D G3DSA:1.10.3720.10 3 256 2.6E-29 T 28-03-2018 CU254_RS10655 959cde7cb43af2c5b729ac7217d74f07 265 SUPERFAMILY SSF161098 18 253 7.57E-42 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS31445 6c61814444fb3ec777dc3a37fcde6e9a 390 Gene3D G3DSA:1.20.1250.20 199 385 4.5E-11 T 28-03-2018 CU254_RS31445 6c61814444fb3ec777dc3a37fcde6e9a 390 Gene3D G3DSA:1.20.1250.20 1 194 6.4E-20 T 28-03-2018 CU254_RS31445 6c61814444fb3ec777dc3a37fcde6e9a 390 Pfam PF07690 Major Facilitator Superfamily 18 344 5.0E-34 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS31445 6c61814444fb3ec777dc3a37fcde6e9a 390 SUPERFAMILY SSF103473 6 377 4.71E-43 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS02425 a3ce6e054dc4b565812d032b53c2488b 141 ProDom PD032647 MB3446 ML0386 RV3412/MT3521 CGL0602 44 134 2.0E-28 T 28-03-2018 IPR035165 Protein of unknown function DUF5319 CU254_RS02425 a3ce6e054dc4b565812d032b53c2488b 141 Pfam PF17252 Family of unknown function (DUF5319) 17 136 1.4E-50 T 28-03-2018 IPR035165 Protein of unknown function DUF5319 CU254_RS11940 0da18041d20c8f2f15eb0856fa60d7c4 174 SUPERFAMILY SSF55729 2 152 1.04E-28 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS11940 0da18041d20c8f2f15eb0856fa60d7c4 174 Gene3D G3DSA:3.40.630.30 1 170 2.7E-19 T 28-03-2018 CU254_RS11940 0da18041d20c8f2f15eb0856fa60d7c4 174 Pfam PF13302 Acetyltransferase (GNAT) domain 10 145 4.4E-20 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS23655 7b95ca33c8bb98c9c3c71a458f1e2763 63 Pfam PF11387 Protein of unknown function (DUF2795) 8 51 1.1E-13 T 28-03-2018 IPR021527 Protein of unknown function DUF2795 CU254_RS25205 a85d3b2973798e22b44fe4eff4263165 132 Pfam PF02575 YbaB/EbfC DNA-binding family 14 99 4.9E-8 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CU254_RS25205 a85d3b2973798e22b44fe4eff4263165 132 Gene3D G3DSA:3.30.1310.10 6 101 1.6E-14 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CU254_RS09100 3be67f58ebb4406a2f4c7cb23ddfebe3 163 Gene3D G3DSA:3.40.1000.10 9 151 1.0E-17 T 28-03-2018 CU254_RS09960 5c70424706a93f5fa08674ee2efe4c0f 413 Pfam PF02470 MlaD protein 38 114 1.3E-14 T 28-03-2018 IPR003399 Mce/MlaD CU254_RS09960 5c70424706a93f5fa08674ee2efe4c0f 413 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 9 293 8.5E-57 T 28-03-2018 IPR005693 Virulence factor Mce protein CU254_RS14280 24850ecfc8613d6910f653760f811c2d 364 Pfam PF01699 Sodium/calcium exchanger protein 220 361 5.1E-13 T 28-03-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 CU254_RS14280 24850ecfc8613d6910f653760f811c2d 364 Pfam PF01699 Sodium/calcium exchanger protein 40 187 1.1E-12 T 28-03-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 CU254_RS23640 bb907dc3c4e584e4bb91d704985d07ad 238 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 107 223 3.1E-19 T 28-03-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein CU254_RS25335 5c6ebe2636ba0e8d0d27dadd8bf79195 214 SMART SM00947 42 201 7.7E-44 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CU254_RS25335 5c6ebe2636ba0e8d0d27dadd8bf79195 214 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 54 61 - T 28-03-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CU254_RS25335 5c6ebe2636ba0e8d0d27dadd8bf79195 214 SUPERFAMILY SSF53056 4 200 1.03E-48 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CU254_RS25335 5c6ebe2636ba0e8d0d27dadd8bf79195 214 Pfam PF00484 Carbonic anhydrase 49 196 1.6E-33 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CU254_RS25335 5c6ebe2636ba0e8d0d27dadd8bf79195 214 Gene3D G3DSA:3.40.1050.10 1 205 2.7E-54 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CU254_RS15365 2680b27672404d7657a7b65db187e290 214 SUPERFAMILY SSF81296 31 213 2.94E-46 T 28-03-2018 IPR014756 Immunoglobulin E-set CU254_RS15365 2680b27672404d7657a7b65db187e290 214 Gene3D G3DSA:2.70.50.50 31 214 4.3E-57 T 28-03-2018 CU254_RS15365 2680b27672404d7657a7b65db187e290 214 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 31 211 1.4E-41 T 28-03-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal CU254_RS24410 5a8753fbd28c4c345e0cc2235bdc0c2b 437 Gene3D G3DSA:1.10.10.10 1 75 3.3E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS24410 5a8753fbd28c4c345e0cc2235bdc0c2b 437 Gene3D G3DSA:2.60.40.1240 303 434 8.0E-8 T 28-03-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain CU254_RS25360 114e69e3d5a62669aee61b0e0c9def10 253 Gene3D G3DSA:3.40.50.880 11 232 8.4E-43 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS25360 114e69e3d5a62669aee61b0e0c9def10 253 Pfam PF03575 Peptidase family S51 13 212 2.9E-55 T 28-03-2018 IPR005320 Peptidase S51 GO:0006508|GO:0008236 CU254_RS25360 114e69e3d5a62669aee61b0e0c9def10 253 SUPERFAMILY SSF52317 13 214 2.65E-35 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS18630 5b04ea03959ee088a4c5443930909072 380 Pfam PF07883 Cupin domain 111 178 7.5E-18 T 28-03-2018 IPR013096 Cupin 2, conserved barrel CU254_RS18630 5b04ea03959ee088a4c5443930909072 380 SUPERFAMILY SSF51182 25 377 4.18E-91 T 28-03-2018 IPR011051 RmlC-like cupin domain CU254_RS18630 5b04ea03959ee088a4c5443930909072 380 Gene3D G3DSA:2.60.120.10 50 375 4.2E-30 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS01190 85e740e53a4a6eff08502837759fa82a 400 Pfam PF02687 FtsX-like permease family 308 391 9.3E-10 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CU254_RS01190 85e740e53a4a6eff08502837759fa82a 400 Pfam PF12704 MacB-like periplasmic core domain 21 241 5.5E-34 T 28-03-2018 IPR025857 MacB-like periplasmic core domain CU254_RS31585 1d0415bd54e3999252bc6c02373e10cc 212 Pfam PF00196 Bacterial regulatory proteins, luxR family 151 206 2.8E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS31585 1d0415bd54e3999252bc6c02373e10cc 212 SMART SM00421 149 206 3.0E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS31585 1d0415bd54e3999252bc6c02373e10cc 212 SUPERFAMILY SSF46894 148 212 5.1E-15 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS31585 1d0415bd54e3999252bc6c02373e10cc 212 Gene3D G3DSA:1.10.10.10 48 212 2.0E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS31585 1d0415bd54e3999252bc6c02373e10cc 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 166 3.2E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS31585 1d0415bd54e3999252bc6c02373e10cc 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 182 3.2E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS31585 1d0415bd54e3999252bc6c02373e10cc 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 194 3.2E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CU254_RS25725 abb63d435883a110b3fbd07ce6a81a56 470 Pfam PF01425 Amidase 27 447 1.8E-104 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS25725 abb63d435883a110b3fbd07ce6a81a56 470 ProSitePatterns PS00571 Amidases signature. 155 186 - T 28-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CU254_RS25725 abb63d435883a110b3fbd07ce6a81a56 470 SUPERFAMILY SSF75304 6 467 2.22E-138 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS25725 abb63d435883a110b3fbd07ce6a81a56 470 Gene3D G3DSA:3.90.1300.10 2 470 1.8E-142 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS06605 4eae3f4c5dd443ec58703a28e4e296b2 324 SUPERFAMILY SSF51735 30 285 1.04E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS06605 4eae3f4c5dd443ec58703a28e4e296b2 324 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 30 47 3.5E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS06605 4eae3f4c5dd443ec58703a28e4e296b2 324 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 229 3.5E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS06605 4eae3f4c5dd443ec58703a28e4e296b2 324 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 103 114 3.5E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS06605 4eae3f4c5dd443ec58703a28e4e296b2 324 Gene3D G3DSA:3.40.50.720 15 324 1.1E-54 T 28-03-2018 CU254_RS06605 4eae3f4c5dd443ec58703a28e4e296b2 324 Pfam PF00106 short chain dehydrogenase 30 234 1.3E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS07615 e9416155e96ea0771af970f832858939 246 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 6 144 1.1E-17 T 28-03-2018 IPR010419 Carbon monoxide dehydrogenase subunit G CU254_RS07615 e9416155e96ea0771af970f832858939 246 SUPERFAMILY SSF55961 2 147 1.63E-33 T 28-03-2018 CU254_RS07615 e9416155e96ea0771af970f832858939 246 Gene3D G3DSA:3.30.530.20 1 161 1.0E-23 T 28-03-2018 IPR023393 START-like domain CU254_RS21295 04c546717de63825e1ffc4b717240cec 1030 Pfam PF00754 F5/8 type C domain 623 701 8.0E-17 T 28-03-2018 IPR000421 Coagulation factor 5/8 C-terminal domain CU254_RS21295 04c546717de63825e1ffc4b717240cec 1030 Pfam PF00754 F5/8 type C domain 926 1016 1.3E-6 T 28-03-2018 IPR000421 Coagulation factor 5/8 C-terminal domain CU254_RS21295 04c546717de63825e1ffc4b717240cec 1030 SUPERFAMILY SSF49785 921 1016 1.91E-7 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS21295 04c546717de63825e1ffc4b717240cec 1030 Gene3D G3DSA:2.60.120.260 613 725 1.7E-23 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS21295 04c546717de63825e1ffc4b717240cec 1030 SUPERFAMILY SSF49785 618 702 4.4E-17 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS21295 04c546717de63825e1ffc4b717240cec 1030 Gene3D G3DSA:2.60.120.260 509 612 7.9E-5 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS21295 04c546717de63825e1ffc4b717240cec 1030 Gene3D G3DSA:2.60.120.260 912 1029 2.7E-8 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS00985 2904845bbb8dfb0d1562891e10affcba 266 Gene3D G3DSA:3.40.50.150 14 247 5.2E-11 T 28-03-2018 CU254_RS00985 2904845bbb8dfb0d1562891e10affcba 266 SUPERFAMILY SSF53335 14 176 3.56E-11 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS40405 286bc3478cdfac31ec6788ba5c91078e 192 SUPERFAMILY SSF48498 90 188 7.65E-10 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS40405 286bc3478cdfac31ec6788ba5c91078e 192 Gene3D G3DSA:1.10.10.60 7 42 4.2E-9 T 28-03-2018 CU254_RS40405 286bc3478cdfac31ec6788ba5c91078e 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 63 4.7E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS40405 286bc3478cdfac31ec6788ba5c91078e 192 Gene3D G3DSA:1.10.260.40 43 69 6.8E-8 T 28-03-2018 CU254_RS40405 286bc3478cdfac31ec6788ba5c91078e 192 Gene3D G3DSA:1.10.357.10 70 191 9.8E-8 T 28-03-2018 CU254_RS40405 286bc3478cdfac31ec6788ba5c91078e 192 SUPERFAMILY SSF46689 6 86 3.99E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS27700 6e75213334fe1a9d6c283d24df425f57 283 Gene3D G3DSA:2.40.10.10 33 145 4.8E-10 T 28-03-2018 CU254_RS40895 7c765079ddea6f612db9bc907ee8554e 199 Gene3D G3DSA:3.40.50.1010 2 149 5.5E-5 T 28-03-2018 IPR029060 PIN domain-like CU254_RS40895 7c765079ddea6f612db9bc907ee8554e 199 SUPERFAMILY SSF88723 5 120 4.61E-5 T 28-03-2018 IPR029060 PIN domain-like CU254_RS06995 58806fe5abdb93cc0ef519df26b09722 302 Gene3D G3DSA:3.40.190.100 137 249 1.9E-36 T 28-03-2018 CU254_RS06995 58806fe5abdb93cc0ef519df26b09722 302 SUPERFAMILY SSF53850 39 298 5.26E-73 T 28-03-2018 CU254_RS06995 58806fe5abdb93cc0ef519df26b09722 302 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 41 289 4.3E-65 T 28-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 CU254_RS06995 58806fe5abdb93cc0ef519df26b09722 302 Gene3D G3DSA:3.40.190.10 40 136 2.0E-17 T 28-03-2018 CU254_RS33480 946c4a47230bc8c9e0a56a8da50f1081 496 Gene3D G3DSA:3.40.50.1820 17 483 1.5E-59 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS33480 946c4a47230bc8c9e0a56a8da50f1081 496 SUPERFAMILY SSF53474 31 481 3.59E-71 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS33480 946c4a47230bc8c9e0a56a8da50f1081 496 Pfam PF00450 Serine carboxypeptidase 81 455 7.3E-11 T 28-03-2018 IPR001563 Peptidase S10, serine carboxypeptidase GO:0004185|GO:0006508 CU254_RS04150 c0fec02003ff28bcb78c8b7f4439a447 282 Pfam PF06271 RDD family 19 150 1.2E-17 T 28-03-2018 IPR010432 RDD CU254_RS40175 e33756fdd7a055ae83baa2cc3a9d5b54 178 Pfam PF14024 Protein of unknown function (DUF4240) 2 131 1.3E-37 T 28-03-2018 IPR025334 Domain of unknown function (DUF4240 CU254_RS17825 215d50cc34480cc6b01eec0c61347837 373 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 179 369 2.7E-45 T 28-03-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0016708|GO:0019439|GO:0051537|GO:0055114 CU254_RS17825 215d50cc34480cc6b01eec0c61347837 373 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 51 66 2.6E-22 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CU254_RS17825 215d50cc34480cc6b01eec0c61347837 373 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 72 92 2.6E-22 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CU254_RS17825 215d50cc34480cc6b01eec0c61347837 373 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 94 114 2.6E-22 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CU254_RS17825 215d50cc34480cc6b01eec0c61347837 373 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 179 201 2.6E-22 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CU254_RS17825 215d50cc34480cc6b01eec0c61347837 373 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 21 46 2.6E-22 T 28-03-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0005506|GO:0006725|GO:0051537|GO:0055114 CU254_RS17825 215d50cc34480cc6b01eec0c61347837 373 SUPERFAMILY SSF50022 12 150 5.89E-44 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CU254_RS17825 215d50cc34480cc6b01eec0c61347837 373 Gene3D G3DSA:2.102.10.10 28 138 3.5E-20 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CU254_RS17825 215d50cc34480cc6b01eec0c61347837 373 SUPERFAMILY SSF55961 172 369 8.63E-43 T 28-03-2018 CU254_RS17825 215d50cc34480cc6b01eec0c61347837 373 Gene3D G3DSA:3.90.380.10 139 372 2.8E-60 T 28-03-2018 CU254_RS17825 215d50cc34480cc6b01eec0c61347837 373 Pfam PF00355 Rieske [2Fe-2S] domain 37 119 5.4E-19 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CU254_RS34805 8c0a61102acca82f8bf7394489881571 145 SMART SM00422 5 73 3.0E-18 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS34805 8c0a61102acca82f8bf7394489881571 145 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 6 17 2.5E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS34805 8c0a61102acca82f8bf7394489881571 145 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 17 30 2.5E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS34805 8c0a61102acca82f8bf7394489881571 145 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 40 60 2.5E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS34805 8c0a61102acca82f8bf7394489881571 145 SUPERFAMILY SSF46955 5 121 1.21E-23 T 28-03-2018 IPR009061 Putative DNA-binding domain CU254_RS34805 8c0a61102acca82f8bf7394489881571 145 Pfam PF13411 MerR HTH family regulatory protein 6 70 7.4E-15 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS34805 8c0a61102acca82f8bf7394489881571 145 Gene3D G3DSA:1.10.1660.10 59 130 7.3E-7 T 28-03-2018 CU254_RS34805 8c0a61102acca82f8bf7394489881571 145 Gene3D G3DSA:1.10.1660.10 2 58 5.3E-18 T 28-03-2018 CU254_RS35105 32e6b9720a2e6082e51337708545041d 930 Gene3D G3DSA:3.30.565.10 44 210 6.0E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS35105 32e6b9720a2e6082e51337708545041d 930 SUPERFAMILY SSF55874 50 179 1.34E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS32475 53f37d6197ca99747d5653847598e691 374 SUPERFAMILY SSF51905 3 217 6.91E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS32475 53f37d6197ca99747d5653847598e691 374 SUPERFAMILY SSF51905 315 372 6.91E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS32475 53f37d6197ca99747d5653847598e691 374 Gene3D G3DSA:3.30.9.10 65 315 2.8E-42 T 28-03-2018 CU254_RS32475 53f37d6197ca99747d5653847598e691 374 SUPERFAMILY SSF54373 216 315 1.45E-21 T 28-03-2018 CU254_RS32475 53f37d6197ca99747d5653847598e691 374 Pfam PF01266 FAD dependent oxidoreductase 5 354 3.1E-44 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CU254_RS32475 53f37d6197ca99747d5653847598e691 374 Gene3D G3DSA:3.40.50.720 2 64 6.7E-5 T 28-03-2018 CU254_RS32475 53f37d6197ca99747d5653847598e691 374 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 8 21 - T 28-03-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 CU254_RS21720 0f09d52424b2e125059354013442fbf2 413 SUPERFAMILY SSF53901 217 406 1.94E-61 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS21720 0f09d52424b2e125059354013442fbf2 413 Gene3D G3DSA:3.40.47.10 260 407 1.2E-45 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS21720 0f09d52424b2e125059354013442fbf2 413 SUPERFAMILY SSF53901 9 251 3.67E-46 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS21720 0f09d52424b2e125059354013442fbf2 413 SMART SM00825 Beta-ketoacyl synthase 11 402 1.1E-15 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CU254_RS21720 0f09d52424b2e125059354013442fbf2 413 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 254 364 1.1E-32 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CU254_RS21720 0f09d52424b2e125059354013442fbf2 413 Gene3D G3DSA:3.40.47.10 1 258 1.2E-55 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CU254_RS21720 0f09d52424b2e125059354013442fbf2 413 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 9 243 1.3E-30 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CU254_RS01455 2a2fbd3254d7d19e1f9312e708b111d5 281 SUPERFAMILY SSF55909 17 281 4.12E-52 T 28-03-2018 CU254_RS01455 2a2fbd3254d7d19e1f9312e708b111d5 281 Gene3D G3DSA:3.75.10.10 12 279 3.8E-60 T 28-03-2018 CU254_RS01455 2a2fbd3254d7d19e1f9312e708b111d5 281 Pfam PF02274 Amidinotransferase 70 280 1.3E-11 T 28-03-2018 CU254_RS40160 1520a2dac0c6482c41f590c1f390b49a 388 SUPERFAMILY SSF56059 270 384 3.53E-72 T 28-03-2018 CU254_RS40160 1520a2dac0c6482c41f590c1f390b49a 388 SUPERFAMILY SSF56059 4 167 3.53E-72 T 28-03-2018 CU254_RS40160 1520a2dac0c6482c41f590c1f390b49a 388 Pfam PF03738 Glutathionylspermidine synthase preATP-grasp 12 385 1.8E-143 T 28-03-2018 IPR005494 Glutathionylspermidine synthase, pre-ATP-grasp-like domain CU254_RS40160 1520a2dac0c6482c41f590c1f390b49a 388 SUPERFAMILY SSF52440 174 283 1.73E-31 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CU254_RS34735 2e303ab45233c1afb7449807594ebbd7 571 SUPERFAMILY SSF56300 93 178 3.49E-30 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CU254_RS34735 2e303ab45233c1afb7449807594ebbd7 571 SUPERFAMILY SSF56300 237 264 3.49E-30 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CU254_RS34735 2e303ab45233c1afb7449807594ebbd7 571 SUPERFAMILY SSF56300 331 506 3.49E-30 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CU254_RS34735 2e303ab45233c1afb7449807594ebbd7 571 Gene3D G3DSA:3.60.21.10 92 515 3.5E-29 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CU254_RS34735 2e303ab45233c1afb7449807594ebbd7 571 TIGRFAM TIGR03767 P_acnes_RR: metallophosphoesterase, PPA1498 family 58 569 1.4E-210 T 28-03-2018 IPR022506 Metallophosphoesterase, PPA1498 CU254_RS34735 2e303ab45233c1afb7449807594ebbd7 571 Pfam PF00149 Calcineurin-like phosphoesterase 93 313 1.5E-4 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CU254_RS13110 7c5a670b0a270f8e67210fa13efe4277 192 Pfam PF12840 Helix-turn-helix domain 12 67 8.1E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS13110 7c5a670b0a270f8e67210fa13efe4277 192 SUPERFAMILY SSF46785 1 83 8.83E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS13110 7c5a670b0a270f8e67210fa13efe4277 192 Gene3D G3DSA:1.10.10.10 3 176 1.1E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS04930 5dcd3028559e9dae5b8874df6e3afc5c 398 Pfam PF01546 Peptidase family M20/M25/M40 71 394 2.2E-24 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CU254_RS04930 5dcd3028559e9dae5b8874df6e3afc5c 398 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 9 393 1.3E-82 T 28-03-2018 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 CU254_RS04930 5dcd3028559e9dae5b8874df6e3afc5c 398 SUPERFAMILY SSF55031 209 316 8.9E-18 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CU254_RS04930 5dcd3028559e9dae5b8874df6e3afc5c 398 PIRSF PIRSF001235 6 398 4.5E-109 T 28-03-2018 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 CU254_RS04930 5dcd3028559e9dae5b8874df6e3afc5c 398 Gene3D G3DSA:3.40.630.10 7 398 6.4E-50 T 28-03-2018 CU254_RS04930 5dcd3028559e9dae5b8874df6e3afc5c 398 SUPERFAMILY SSF53187 327 397 2.68E-65 T 28-03-2018 CU254_RS04930 5dcd3028559e9dae5b8874df6e3afc5c 398 SUPERFAMILY SSF53187 17 216 2.68E-65 T 28-03-2018 CU254_RS14520 e44ffc01adb4fba0708dce5fb18815ce 396 SUPERFAMILY SSF89796 1 388 3.66E-130 T 28-03-2018 IPR023606 CoA-transferase family III domain CU254_RS14520 e44ffc01adb4fba0708dce5fb18815ce 396 Gene3D G3DSA:3.40.50.10540 1 393 2.7E-139 T 28-03-2018 IPR023606 CoA-transferase family III domain CU254_RS14520 e44ffc01adb4fba0708dce5fb18815ce 396 Pfam PF02515 CoA-transferase family III 4 366 1.8E-120 T 28-03-2018 IPR003673 CoA-transferase family III GO:0003824 CU254_RS35330 5093285f8df61499b5fa458f7a6739b7 225 SUPERFAMILY SSF110395 7 223 3.79E-50 T 28-03-2018 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 CU254_RS35330 5093285f8df61499b5fa458f7a6739b7 225 Pfam PF03932 CutC family 7 198 4.9E-36 T 28-03-2018 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 CU254_RS35330 5093285f8df61499b5fa458f7a6739b7 225 Gene3D G3DSA:3.20.20.380 7 225 5.1E-62 T 28-03-2018 CU254_RS20080 1dd6b08c7760245591259d020635d60e 433 Pfam PF01183 Glycosyl hydrolases family 25 44 228 6.6E-48 T 28-03-2018 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 CU254_RS20080 1dd6b08c7760245591259d020635d60e 433 SUPERFAMILY SSF51445 40 246 7.72E-65 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS20080 1dd6b08c7760245591259d020635d60e 433 Gene3D G3DSA:3.20.20.80 29 254 3.2E-66 T 28-03-2018 CU254_RS20080 1dd6b08c7760245591259d020635d60e 433 SMART SM00641 41 150 6.2E-46 T 28-03-2018 IPR018077 Glycoside hydrolase, family 25 subgroup CU254_RS20080 1dd6b08c7760245591259d020635d60e 433 ProSitePatterns PS00953 Glycosyl hydrolases family 25 active sites signature. 45 78 - T 28-03-2018 IPR008270 Glycoside hydrolase, family 25, active site GO:0003796|GO:0009253|GO:0016998 CU254_RS02345 cbd71a870ff0e9f707d084e1a241e758 59 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 18 51 1.9E-5 T 28-03-2018 CU254_RS02345 cbd71a870ff0e9f707d084e1a241e758 59 Gene3D G3DSA:1.10.3720.10 5 58 9.5E-4 T 28-03-2018 CU254_RS05240 b13be42af5ec6b1695b84e9b1cac79cb 138 Gene3D G3DSA:3.10.180.10 2 137 3.2E-23 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS05240 b13be42af5ec6b1695b84e9b1cac79cb 138 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 128 4.0E-9 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CU254_RS05240 b13be42af5ec6b1695b84e9b1cac79cb 138 SUPERFAMILY SSF54593 6 132 3.89E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS04905 49264be741625252b5039cc2afd6ada2 225 Pfam PF16715 Cyclodipeptide synthase 6 224 2.7E-70 T 28-03-2018 IPR030903 Cyclodileucine synthase GO:0016755 CU254_RS04905 49264be741625252b5039cc2afd6ada2 225 TIGRFAM TIGR04539 tRNA_cyclodipep: tRNA-dependent cyclodipeptide synthase 6 224 4.1E-78 T 28-03-2018 IPR030903 Cyclodileucine synthase GO:0016755 CU254_RS31005 3274b421e1fd793b294954545b698ba2 185 Pfam PF09438 Domain of unknown function (DUF2017) 6 183 2.3E-63 T 28-03-2018 IPR018561 Domain of unknown function DUF2017 CU254_RS39030 400253ea42982a429ae7e76b064b9d6e 340 Gene3D G3DSA:2.130.10.120 51 306 3.6E-4 T 28-03-2018 CU254_RS39030 400253ea42982a429ae7e76b064b9d6e 340 SUPERFAMILY SSF50965 168 287 1.14E-5 T 28-03-2018 IPR011043 Galactose oxidase/kelch, beta-propeller CU254_RS09765 5ca518ccef2bf9c7ed5bc50e72dbf635 938 Pfam PF02867 Ribonucleotide reductase, barrel domain 156 691 2.3E-142 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CU254_RS09765 5ca518ccef2bf9c7ed5bc50e72dbf635 938 Gene3D G3DSA:3.20.70.20 47 698 2.9E-171 T 28-03-2018 CU254_RS09765 5ca518ccef2bf9c7ed5bc50e72dbf635 938 Pfam PF08471 Class II vitamin B12-dependent ribonucleotide reductase 52 135 1.2E-18 T 28-03-2018 IPR013678 Ribonucleotide reductase class II vitamin B12-dependent, N-terminal domain GO:0004748|GO:0050897|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CU254_RS09765 5ca518ccef2bf9c7ed5bc50e72dbf635 938 SUPERFAMILY SSF51998 156 587 1.62E-130 T 28-03-2018 CU254_RS09765 5ca518ccef2bf9c7ed5bc50e72dbf635 938 SUPERFAMILY SSF51998 621 695 1.62E-130 T 28-03-2018 CU254_RS09765 5ca518ccef2bf9c7ed5bc50e72dbf635 938 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 91 701 5.5E-186 T 28-03-2018 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CU254_RS09765 5ca518ccef2bf9c7ed5bc50e72dbf635 938 PRINTS PR01183 Ribonucleotide reductase large chain signature 537 564 1.1E-12 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CU254_RS09765 5ca518ccef2bf9c7ed5bc50e72dbf635 938 PRINTS PR01183 Ribonucleotide reductase large chain signature 231 250 1.1E-12 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CU254_RS09765 5ca518ccef2bf9c7ed5bc50e72dbf635 938 PRINTS PR01183 Ribonucleotide reductase large chain signature 392 415 1.1E-12 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CU254_RS09765 5ca518ccef2bf9c7ed5bc50e72dbf635 938 PRINTS PR01183 Ribonucleotide reductase large chain signature 358 369 1.1E-12 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CU254_RS09765 5ca518ccef2bf9c7ed5bc50e72dbf635 938 PRINTS PR01183 Ribonucleotide reductase large chain signature 430 452 1.1E-12 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CU254_RS19520 6bb8637575cb1bb40e06896da2bb410f 210 SUPERFAMILY SSF53335 18 188 5.27E-39 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS19520 6bb8637575cb1bb40e06896da2bb410f 210 Pfam PF13649 Methyltransferase domain 51 144 2.4E-20 T 28-03-2018 CU254_RS19520 6bb8637575cb1bb40e06896da2bb410f 210 Gene3D G3DSA:3.40.50.150 2 204 2.7E-30 T 28-03-2018 CU254_RS40825 74e61039f38773f89035b3416d8e9d90 391 Gene3D G3DSA:1.20.1250.20 203 388 3.2E-12 T 28-03-2018 CU254_RS40825 74e61039f38773f89035b3416d8e9d90 391 SUPERFAMILY SSF103473 6 385 1.31E-45 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS40825 74e61039f38773f89035b3416d8e9d90 391 Gene3D G3DSA:1.20.1250.20 5 195 6.0E-21 T 28-03-2018 CU254_RS40825 74e61039f38773f89035b3416d8e9d90 391 Pfam PF07690 Major Facilitator Superfamily 22 354 1.8E-32 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS28795 edc8a6d7aab15fe097fc27a1b09c0c7a 400 Gene3D G3DSA:3.40.50.1970 5 192 6.4E-27 T 28-03-2018 CU254_RS28795 edc8a6d7aab15fe097fc27a1b09c0c7a 400 Pfam PF00465 Iron-containing alcohol dehydrogenase 14 303 1.6E-26 T 28-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 CU254_RS28795 edc8a6d7aab15fe097fc27a1b09c0c7a 400 SUPERFAMILY SSF56796 14 270 8.64E-25 T 28-03-2018 CU254_RS07960 76528e4fcb297803329b031540e72cc5 263 Pfam PF02517 CAAX protease self-immunity 156 248 8.2E-14 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CU254_RS01305 7e111b5f62fbab96addff57ec326d09f 277 SUPERFAMILY SSF56655 18 273 3.14E-52 T 28-03-2018 CU254_RS01305 7e111b5f62fbab96addff57ec326d09f 277 Pfam PF00459 Inositol monophosphatase family 21 266 7.9E-43 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CU254_RS01305 7e111b5f62fbab96addff57ec326d09f 277 PRINTS PR00377 Inositol monophosphatase superfamily signature 222 246 5.4E-29 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CU254_RS01305 7e111b5f62fbab96addff57ec326d09f 277 PRINTS PR00377 Inositol monophosphatase superfamily signature 53 73 5.4E-29 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CU254_RS01305 7e111b5f62fbab96addff57ec326d09f 277 PRINTS PR00377 Inositol monophosphatase superfamily signature 97 113 5.4E-29 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CU254_RS01305 7e111b5f62fbab96addff57ec326d09f 277 PRINTS PR00377 Inositol monophosphatase superfamily signature 75 91 5.4E-29 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CU254_RS01305 7e111b5f62fbab96addff57ec326d09f 277 PRINTS PR00377 Inositol monophosphatase superfamily signature 146 169 5.4E-29 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CU254_RS01305 7e111b5f62fbab96addff57ec326d09f 277 PRINTS PR00377 Inositol monophosphatase superfamily signature 191 212 5.4E-29 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CU254_RS01305 7e111b5f62fbab96addff57ec326d09f 277 Gene3D G3DSA:3.40.190.80 153 277 1.1E-19 T 28-03-2018 CU254_RS01305 7e111b5f62fbab96addff57ec326d09f 277 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 225 239 - T 28-03-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 CU254_RS01305 7e111b5f62fbab96addff57ec326d09f 277 Gene3D G3DSA:3.30.540.10 14 152 5.0E-35 T 28-03-2018 CU254_RS40280 2cf9901dda0949d322a70f743d386803 414 Pfam PF05893 Acyl-CoA reductase (LuxC) 89 408 1.5E-35 T 28-03-2018 IPR008670 Long-chain-fatty-acyl-CoA reductase, LuxC GO:0003995|GO:0008218|GO:0055114 KEGG: 00073+1.2.1.50|MetaCyc: PWY-7723 CU254_RS40280 2cf9901dda0949d322a70f743d386803 414 Gene3D G3DSA:3.40.605.10 37 255 3.4E-10 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CU254_RS40280 2cf9901dda0949d322a70f743d386803 414 SUPERFAMILY SSF53720 88 153 7.33E-6 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CU254_RS42370 b0f71fe0976195a8674999fe89645ee7 433 Gene3D G3DSA:1.20.58.60 37 353 0.0016 T 28-03-2018 CU254_RS29385 2743233b93a4e4c8fed4c79a6be45ecd 281 SUPERFAMILY SSF53335 17 259 4.45E-32 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS29385 2743233b93a4e4c8fed4c79a6be45ecd 281 PIRSF PIRSF017393 1 281 2.1E-83 T 28-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CU254_RS29385 2743233b93a4e4c8fed4c79a6be45ecd 281 Gene3D G3DSA:3.40.50.150 2 281 1.4E-43 T 28-03-2018 CU254_RS29385 2743233b93a4e4c8fed4c79a6be45ecd 281 Pfam PF04672 S-adenosyl methyltransferase 11 281 1.6E-78 T 28-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CU254_RS41350 d37290c7ad9582b274381e71e1f853e2 149 Gene3D G3DSA:3.30.450.30 6 114 3.0E-4 T 28-03-2018 CU254_RS26245 8cd30c992649c3d9948554029ff19a3a 541 Pfam PF02384 N-6 DNA Methylase 177 503 1.5E-120 T 28-03-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 CU254_RS26245 8cd30c992649c3d9948554029ff19a3a 541 Gene3D G3DSA:3.40.50.150 199 496 1.7E-60 T 28-03-2018 CU254_RS26245 8cd30c992649c3d9948554029ff19a3a 541 Pfam PF12161 HsdM N-terminal domain 18 164 2.5E-24 T 28-03-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain CU254_RS26245 8cd30c992649c3d9948554029ff19a3a 541 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 201 217 4.3E-20 T 28-03-2018 CU254_RS26245 8cd30c992649c3d9948554029ff19a3a 541 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 299 311 4.3E-20 T 28-03-2018 CU254_RS26245 8cd30c992649c3d9948554029ff19a3a 541 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 331 355 4.3E-20 T 28-03-2018 CU254_RS26245 8cd30c992649c3d9948554029ff19a3a 541 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 224 238 4.3E-20 T 28-03-2018 CU254_RS26245 8cd30c992649c3d9948554029ff19a3a 541 SUPERFAMILY SSF53335 16 55 1.14E-137 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS26245 8cd30c992649c3d9948554029ff19a3a 541 SUPERFAMILY SSF53335 89 540 1.14E-137 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS14460 ea860547f820e4e0aff23b8caef63a27 195 SUPERFAMILY SSF160631 25 141 7.06E-10 T 28-03-2018 CU254_RS14460 ea860547f820e4e0aff23b8caef63a27 195 Pfam PF14568 SMI1-KNR4 cell-wall 25 153 2.7E-7 T 28-03-2018 CU254_RS14460 ea860547f820e4e0aff23b8caef63a27 195 Gene3D G3DSA:3.40.1580.10 23 169 1.6E-11 T 28-03-2018 CU254_RS30320 67e65374c93c6b81a7e04785bedfa3d3 234 Pfam PF13490 Putative zinc-finger 11 37 1.6E-6 T 28-03-2018 IPR027383 Putative zinc-finger CU254_RS11565 f0519bb8a4df1aa277422777e1aaf45f 152 Gene3D G3DSA:1.10.10.410 94 150 1.3E-15 T 28-03-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal CU254_RS11565 f0519bb8a4df1aa277422777e1aaf45f 152 Pfam PF09424 Yqey-like protein 6 149 3.2E-48 T 28-03-2018 IPR019004 Uncharacterised domain YOR215C, mitochondrial CU254_RS11565 f0519bb8a4df1aa277422777e1aaf45f 152 SUPERFAMILY SSF89095 3 149 2.46E-35 T 28-03-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 CU254_RS11565 f0519bb8a4df1aa277422777e1aaf45f 152 Gene3D G3DSA:1.10.1510.10 1 93 9.9E-28 T 28-03-2018 CU254_RS10685 947c0b5f4a1b920f2ec8010dfe16769a 141 Gene3D G3DSA:3.50.80.10 1 141 1.4E-48 T 28-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain CU254_RS10685 947c0b5f4a1b920f2ec8010dfe16769a 141 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 3 141 1.7E-38 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 CU254_RS10685 947c0b5f4a1b920f2ec8010dfe16769a 141 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 141 29.57 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 CU254_RS10685 947c0b5f4a1b920f2ec8010dfe16769a 141 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 140 2.0E-48 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 CU254_RS10685 947c0b5f4a1b920f2ec8010dfe16769a 141 SUPERFAMILY SSF69500 2 140 1.44E-42 T 28-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain CU254_RS31555 0068cc3bd6a8abe8a49f5901433a2eda 227 Pfam PF12385 Papain-like cysteine protease AvrRpt2 73 210 3.9E-13 T 28-03-2018 IPR022118 Peptidase C70, AvrRpt2 CU254_RS31555 0068cc3bd6a8abe8a49f5901433a2eda 227 Gene3D G3DSA:3.90.70.10 63 224 3.4E-22 T 28-03-2018 CU254_RS29470 f4028f805ebe07bab34fae42e1dd5cd9 158 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 7 53 4.4E-5 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CU254_RS29470 f4028f805ebe07bab34fae42e1dd5cd9 158 Gene3D G3DSA:3.10.20.30 1 76 6.2E-20 T 28-03-2018 IPR012675 Beta-grasp domain CU254_RS29470 f4028f805ebe07bab34fae42e1dd5cd9 158 Gene3D G3DSA:1.10.150.120 77 158 1.4E-24 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CU254_RS29470 f4028f805ebe07bab34fae42e1dd5cd9 158 Pfam PF01799 [2Fe-2S] binding domain 75 152 1.6E-23 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CU254_RS29470 f4028f805ebe07bab34fae42e1dd5cd9 158 SUPERFAMILY SSF47741 88 156 6.8E-25 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CU254_RS29470 f4028f805ebe07bab34fae42e1dd5cd9 158 SUPERFAMILY SSF54292 4 81 6.06E-19 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CU254_RS13215 e5aa09103d271efe0f8c174091ce57db 299 SUPERFAMILY SSF56059 91 273 4.12E-13 T 28-03-2018 CU254_RS13215 e5aa09103d271efe0f8c174091ce57db 299 Gene3D G3DSA:3.30.470.20 84 278 7.9E-13 T 28-03-2018 CU254_RS27860 21eb1de7f67fc99064b9d64bbfeb05ce 515 Gene3D G3DSA:3.50.50.60 2 372 7.8E-60 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS27860 21eb1de7f67fc99064b9d64bbfeb05ce 515 SUPERFAMILY SSF51905 280 362 4.11E-60 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS27860 21eb1de7f67fc99064b9d64bbfeb05ce 515 SUPERFAMILY SSF51905 6 189 4.11E-60 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS27860 21eb1de7f67fc99064b9d64bbfeb05ce 515 Pfam PF01494 FAD binding domain 5 358 4.1E-91 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CU254_RS27860 21eb1de7f67fc99064b9d64bbfeb05ce 515 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 168 183 2.8E-40 T 28-03-2018 CU254_RS27860 21eb1de7f67fc99064b9d64bbfeb05ce 515 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 344 360 2.8E-40 T 28-03-2018 CU254_RS27860 21eb1de7f67fc99064b9d64bbfeb05ce 515 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 326 344 2.8E-40 T 28-03-2018 CU254_RS27860 21eb1de7f67fc99064b9d64bbfeb05ce 515 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 2.8E-40 T 28-03-2018 CU254_RS27860 21eb1de7f67fc99064b9d64bbfeb05ce 515 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 293 308 2.8E-40 T 28-03-2018 CU254_RS27860 21eb1de7f67fc99064b9d64bbfeb05ce 515 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 308 324 2.8E-40 T 28-03-2018 CU254_RS39415 c7069445ebeb159deb2832a33f826672 88 Hamap MF_00631 Cell division protein CrgA [crgA]. 1 88 23.112 T 28-03-2018 IPR009619 Cell division protein CrgA CU254_RS39415 c7069445ebeb159deb2832a33f826672 88 Pfam PF06781 Cell division protein CrgA 1 88 9.5E-38 T 28-03-2018 IPR009619 Cell division protein CrgA CU254_RS11830 19df9acd2e5842a34907e99c10bb049d 132 SUPERFAMILY SSF117916 33 126 8.5E-28 T 28-03-2018 IPR034904 Fe-S cluster assembly domain CU254_RS11830 19df9acd2e5842a34907e99c10bb049d 132 Gene3D G3DSA:3.30.300.130 30 127 1.3E-24 T 28-03-2018 IPR034904 Fe-S cluster assembly domain CU254_RS11830 19df9acd2e5842a34907e99c10bb049d 132 Pfam PF01883 Iron-sulfur cluster assembly protein 33 100 3.1E-19 T 28-03-2018 IPR002744 MIP18 family-like CU254_RS25860 32bff50c9bf7b3e0536091d2367d0a74 185 Pfam PF13298 DNA polymerase Ligase (LigD) 36 140 8.4E-39 T 28-03-2018 IPR014144 DNA ligase D, 3'-phosphoesterase domain CU254_RS25860 32bff50c9bf7b3e0536091d2367d0a74 185 TIGRFAM TIGR02777 LigD_PE_dom: DNA ligase D, 3'-phosphoesterase domain 7 158 3.0E-62 T 28-03-2018 IPR014144 DNA ligase D, 3'-phosphoesterase domain CU254_RS27960 b7cd4b8c92f367b92ff4558c2be685e1 320 SUPERFAMILY SSF53474 57 319 2.88E-57 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS27960 b7cd4b8c92f367b92ff4558c2be685e1 320 Pfam PF07859 alpha/beta hydrolase fold 87 294 8.1E-52 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CU254_RS27960 b7cd4b8c92f367b92ff4558c2be685e1 320 Gene3D G3DSA:3.40.50.1820 6 320 6.2E-53 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS04455 b669e29fd0ff446ec2682a8d39aba2d2 519 Pfam PF00561 alpha/beta hydrolase fold 102 492 1.8E-48 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS04455 b669e29fd0ff446ec2682a8d39aba2d2 519 SUPERFAMILY SSF53474 80 148 7.69E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS04455 b669e29fd0ff446ec2682a8d39aba2d2 519 SUPERFAMILY SSF53474 422 490 7.69E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS04455 b669e29fd0ff446ec2682a8d39aba2d2 519 SUPERFAMILY SSF53474 185 277 7.69E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS04455 b669e29fd0ff446ec2682a8d39aba2d2 519 Gene3D G3DSA:3.40.50.1820 77 506 1.3E-41 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS15220 c777bac77e40c2842c468d5107787876 94 TIGRFAM TIGR04076 TIGR04076: TIGR04076 family protein 10 92 3.7E-13 T 28-03-2018 IPR023811 Conserved hypothetical protein CHP04076 CU254_RS11220 644f7e695012574f6f6ff2cccded7d23 151 Pfam PF03780 Asp23 family, cell envelope-related function 27 137 5.0E-29 T 28-03-2018 IPR005531 Alkaline shock protein Asp23 CU254_RS28700 85c878415a79032bfa7084bfc16b92ca 439 SUPERFAMILY SSF53448 35 301 1.21E-28 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS28700 85c878415a79032bfa7084bfc16b92ca 439 Pfam PF13641 Glycosyltransferase like family 2 34 283 7.6E-26 T 28-03-2018 CU254_RS28700 85c878415a79032bfa7084bfc16b92ca 439 Gene3D G3DSA:3.90.550.10 18 306 5.7E-31 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS31175 654869525ed03dc6a6bf18617448fff8 257 Gene3D G3DSA:3.90.226.10 1 257 5.9E-63 T 28-03-2018 CU254_RS31175 654869525ed03dc6a6bf18617448fff8 257 SUPERFAMILY SSF52096 3 257 7.82E-67 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS31175 654869525ed03dc6a6bf18617448fff8 257 Pfam PF00378 Enoyl-CoA hydratase/isomerase 16 257 9.9E-47 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CU254_RS24395 d5b57c4452a1e17360a1da7a2b90e5d7 346 Pfam PF00296 Luciferase-like monooxygenase 5 320 6.1E-71 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS24395 d5b57c4452a1e17360a1da7a2b90e5d7 346 Gene3D G3DSA:3.20.20.30 1 345 2.5E-62 T 28-03-2018 CU254_RS24395 d5b57c4452a1e17360a1da7a2b90e5d7 346 TIGRFAM TIGR03559 F420_Rv3520c: probable F420-dependent oxidoreductase, Rv3520c family 2 324 1.6E-156 T 28-03-2018 IPR019951 F420-dependent oxidoreductase-predicted, Rv3520c CU254_RS24395 d5b57c4452a1e17360a1da7a2b90e5d7 346 SUPERFAMILY SSF51679 1 337 5.89E-63 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS26565 4fc7889450508248398894d76ac75064 117 Gene3D G3DSA:3.30.530.20 21 107 0.01 T 28-03-2018 IPR023393 START-like domain CU254_RS01055 6d1191a295c5cef54ab0fd794c0957d2 327 Pfam PF02541 Ppx/GppA phosphatase family 17 305 2.4E-71 T 28-03-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 CU254_RS01055 6d1191a295c5cef54ab0fd794c0957d2 327 Gene3D G3DSA:3.30.420.40 1 124 2.7E-35 T 28-03-2018 CU254_RS01055 6d1191a295c5cef54ab0fd794c0957d2 327 Gene3D G3DSA:3.30.420.150 127 309 4.7E-40 T 28-03-2018 CU254_RS01055 6d1191a295c5cef54ab0fd794c0957d2 327 SUPERFAMILY SSF53067 129 306 8.88E-34 T 28-03-2018 CU254_RS01055 6d1191a295c5cef54ab0fd794c0957d2 327 SUPERFAMILY SSF53067 2 125 1.81E-29 T 28-03-2018 CU254_RS22230 2764a0d6e6fa19646ccf85791a891833 140 Gene3D G3DSA:3.10.180.10 1 139 5.3E-27 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS22230 2764a0d6e6fa19646ccf85791a891833 140 SUPERFAMILY SSF54593 2 120 2.61E-25 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS22230 2764a0d6e6fa19646ccf85791a891833 140 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 117 3.9E-11 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CU254_RS31690 c1e764844ed83f7dd39917a0dbc6bd1f 517 Pfam PF13556 PucR C-terminal helix-turn-helix domain 448 503 4.6E-14 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CU254_RS31690 c1e764844ed83f7dd39917a0dbc6bd1f 517 Pfam PF07905 Purine catabolism regulatory protein-like family 7 128 5.9E-25 T 28-03-2018 IPR012914 Purine catabolism PurC-like domain CU254_RS31690 c1e764844ed83f7dd39917a0dbc6bd1f 517 Gene3D G3DSA:1.10.10.10 419 508 1.7E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS38025 0d4a313baf703a5c059ce486bc3801f5 157 Gene3D G3DSA:2.30.110.10 3 153 2.0E-23 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS38025 0d4a313baf703a5c059ce486bc3801f5 157 SUPERFAMILY SSF50475 7 151 4.12E-27 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS38025 0d4a313baf703a5c059ce486bc3801f5 157 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 12 98 7.2E-13 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CU254_RS19770 e3f6d73be723bd4a8202904b7c5591e4 313 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 16 263 7.9E-69 T 28-03-2018 IPR014145 DNA ligase D, polymerase domain CU254_RS19770 e3f6d73be723bd4a8202904b7c5591e4 313 Pfam PF01896 DNA primase small subunit 149 259 3.2E-7 T 28-03-2018 IPR002755 DNA primase, small subunit GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 CU254_RS05810 20293357ba753a262ecdc468a9cebbea 293 Pfam PF00296 Luciferase-like monooxygenase 19 245 8.1E-21 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS05810 20293357ba753a262ecdc468a9cebbea 293 SUPERFAMILY SSF51679 11 282 3.39E-34 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS05810 20293357ba753a262ecdc468a9cebbea 293 TIGRFAM TIGR03621 F420_MSMEG_2516: probable F420-dependent oxidoreductase, MSMEG_2516 family 8 293 1.3E-90 T 28-03-2018 IPR019923 Luciferase-like, F420-dependent oxidoreductase, MSMEG2516, predicted CU254_RS05810 20293357ba753a262ecdc468a9cebbea 293 Gene3D G3DSA:3.20.20.30 15 289 7.9E-35 T 28-03-2018 CU254_RS00040 ab1a59d4c4f1b8df16ea9651cc46313a 76 Pfam PF14013 MT0933-like antitoxin protein 10 54 5.0E-12 T 28-03-2018 IPR028037 Antitoxin Rv0909/MT0933 CU254_RS00040 ab1a59d4c4f1b8df16ea9651cc46313a 76 Gene3D G3DSA:1.20.120.20 3 65 6.4E-4 T 28-03-2018 CU254_RS26885 624ad3bd0687871f6d2cfa65a12624c5 241 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 20 217 2.0E-25 T 28-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CU254_RS26885 624ad3bd0687871f6d2cfa65a12624c5 241 SUPERFAMILY SSF109854 6 136 3.48E-11 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CU254_RS26885 624ad3bd0687871f6d2cfa65a12624c5 241 Pfam PF07398 MDMPI C-terminal domain 144 231 1.6E-10 T 28-03-2018 IPR010872 MDMPI C-terminal CU254_RS26885 624ad3bd0687871f6d2cfa65a12624c5 241 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 19 130 1.2E-17 T 28-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CU254_RS26885 624ad3bd0687871f6d2cfa65a12624c5 241 Gene3D G3DSA:1.20.120.450 8 137 1.5E-14 T 28-03-2018 CU254_RS39580 437b3073f9cfd24e76d6183618bf134a 343 PIRSF PIRSF001434 1 343 3.1E-86 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CU254_RS39580 437b3073f9cfd24e76d6183618bf134a 343 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 20 342 3.7E-66 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CU254_RS39580 437b3073f9cfd24e76d6183618bf134a 343 Gene3D G3DSA:3.90.1150.10 236 267 4.2E-4 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS39580 437b3073f9cfd24e76d6183618bf134a 343 Gene3D G3DSA:3.90.1150.10 268 343 2.1E-19 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS39580 437b3073f9cfd24e76d6183618bf134a 343 Gene3D G3DSA:3.40.640.10 4 235 1.5E-26 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS39580 437b3073f9cfd24e76d6183618bf134a 343 SUPERFAMILY SSF53383 46 342 8.31E-62 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS09445 3a4655f2e696bef0b1604e5f2fa04a68 139 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 9 87 1.9E-12 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CU254_RS09445 3a4655f2e696bef0b1604e5f2fa04a68 139 Gene3D G3DSA:2.30.110.10 1 132 4.9E-23 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS09445 3a4655f2e696bef0b1604e5f2fa04a68 139 SUPERFAMILY SSF50475 4 124 4.75E-21 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS40385 0d4c0a9ae6b18b7f541a14471e3f7c46 635 Gene3D G3DSA:3.90.550.10 148 459 4.8E-17 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS40385 0d4c0a9ae6b18b7f541a14471e3f7c46 635 SUPERFAMILY SSF53448 350 460 1.88E-28 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS40385 0d4c0a9ae6b18b7f541a14471e3f7c46 635 SUPERFAMILY SSF53448 177 317 1.88E-28 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS40385 0d4c0a9ae6b18b7f541a14471e3f7c46 635 Pfam PF13641 Glycosyltransferase like family 2 177 430 7.3E-33 T 28-03-2018 CU254_RS38620 787bc465a89d3848cad1df6c9499f518 181 Gene3D G3DSA:3.30.1050.10 55 180 1.3E-20 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CU254_RS38620 787bc465a89d3848cad1df6c9499f518 181 Pfam PF02036 SCP-2 sterol transfer family 111 172 1.0E-8 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CU254_RS38620 787bc465a89d3848cad1df6c9499f518 181 SUPERFAMILY SSF55718 62 177 7.06E-19 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CU254_RS36525 1cf16e4760fb20ac3f62536355b7dd56 54 Pfam PF14029 Protein of unknown function (DUF4244) 5 50 4.1E-19 T 28-03-2018 IPR025338 Protein of unknown function DUF4244 CU254_RS33245 b359024f4d591d278a25fa8a651f7dcd 122 Pfam PF08044 Domain of unknown function (DUF1707) 7 59 9.5E-21 T 28-03-2018 IPR012551 Protein of unknown function DUF1707 CU254_RS25685 3ad287d5dd8ea3a5c37c1284e2e9e36f 263 Gene3D G3DSA:3.40.630.30 116 260 9.3E-17 T 28-03-2018 CU254_RS25685 3ad287d5dd8ea3a5c37c1284e2e9e36f 263 SUPERFAMILY SSF55729 21 251 3.42E-24 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS25685 3ad287d5dd8ea3a5c37c1284e2e9e36f 263 Pfam PF00583 Acetyltransferase (GNAT) family 165 248 5.2E-9 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS25685 3ad287d5dd8ea3a5c37c1284e2e9e36f 263 Gene3D G3DSA:3.40.630.30 2 109 0.014 T 28-03-2018 CU254_RS29280 fe2224fcffe78807b5e2b4d6b7e0bc2e 338 SUPERFAMILY SSF53213 66 335 2.62E-45 T 28-03-2018 CU254_RS29280 fe2224fcffe78807b5e2b4d6b7e0bc2e 338 SUPERFAMILY SSF53213 3 26 2.62E-45 T 28-03-2018 CU254_RS29280 fe2224fcffe78807b5e2b4d6b7e0bc2e 338 Gene3D G3DSA:3.40.830.10 1 337 1.7E-38 T 28-03-2018 CU254_RS29280 fe2224fcffe78807b5e2b4d6b7e0bc2e 338 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 69 319 1.8E-19 T 28-03-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 CU254_RS23915 8555339d2a58783e37a37fcf0237d6e8 266 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 29 261 4.7E-57 T 28-03-2018 CU254_RS23915 8555339d2a58783e37a37fcf0237d6e8 266 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 161 189 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS23915 8555339d2a58783e37a37fcf0237d6e8 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 162 2.4E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23915 8555339d2a58783e37a37fcf0237d6e8 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 174 193 2.4E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23915 8555339d2a58783e37a37fcf0237d6e8 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 100 111 2.4E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23915 8555339d2a58783e37a37fcf0237d6e8 266 Gene3D G3DSA:3.40.50.720 66 263 1.5E-52 T 28-03-2018 CU254_RS23915 8555339d2a58783e37a37fcf0237d6e8 266 SUPERFAMILY SSF51735 22 262 1.99E-64 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS23915 8555339d2a58783e37a37fcf0237d6e8 266 Gene3D G3DSA:3.40.50.10090 18 65 1.3E-5 T 28-03-2018 CU254_RS23915 8555339d2a58783e37a37fcf0237d6e8 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 100 111 3.0E-33 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23915 8555339d2a58783e37a37fcf0237d6e8 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 193 3.0E-33 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23915 8555339d2a58783e37a37fcf0237d6e8 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 195 212 3.0E-33 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23915 8555339d2a58783e37a37fcf0237d6e8 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 229 249 3.0E-33 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23915 8555339d2a58783e37a37fcf0237d6e8 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 24 41 3.0E-33 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23915 8555339d2a58783e37a37fcf0237d6e8 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 164 3.0E-33 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS16725 207869b7faa39a930e90e8b2b61c7a67 94 Gene3D G3DSA:2.40.30.100 9 89 4.6E-25 T 28-03-2018 IPR015018 Protein of unknown function DUF1905 CU254_RS16725 207869b7faa39a930e90e8b2b61c7a67 94 Pfam PF08922 Domain of unknown function (DUF1905) 10 88 2.5E-23 T 28-03-2018 IPR015018 Protein of unknown function DUF1905 CU254_RS16725 207869b7faa39a930e90e8b2b61c7a67 94 SUPERFAMILY SSF141694 8 90 4.18E-24 T 28-03-2018 CU254_RS21630 a5fb639cabbfdbd8974a5fff1ada5275 215 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 69 91 - T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CU254_RS21630 a5fb639cabbfdbd8974a5fff1ada5275 215 Pfam PF01066 CDP-alcohol phosphatidyltransferase 27 91 1.1E-8 T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CU254_RS21580 1c6599b617346f443c4a3032ddd6bd52 158 Gene3D G3DSA:2.60.120.10 13 140 5.0E-21 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS21580 1c6599b617346f443c4a3032ddd6bd52 158 SUPERFAMILY SSF51182 25 142 1.54E-25 T 28-03-2018 IPR011051 RmlC-like cupin domain CU254_RS21580 1c6599b617346f443c4a3032ddd6bd52 158 Pfam PF07883 Cupin domain 51 112 1.1E-17 T 28-03-2018 IPR013096 Cupin 2, conserved barrel CU254_RS21870 283a2345b8bb5c9b5e63d7983de603af 360 SUPERFAMILY SSF160991 8 356 3.79E-124 T 28-03-2018 CU254_RS21870 283a2345b8bb5c9b5e63d7983de603af 360 Gene3D G3DSA:3.40.1610.10 5 222 2.3E-79 T 28-03-2018 IPR027479 Protein of unknown function DUF917, N-terminal CU254_RS21870 283a2345b8bb5c9b5e63d7983de603af 360 Gene3D G3DSA:2.40.390.10 223 348 7.3E-42 T 28-03-2018 IPR024071 Protein of unknown function DUF917, C-terminal CU254_RS21870 283a2345b8bb5c9b5e63d7983de603af 360 Pfam PF06032 Protein of unknown function (DUF917) 11 354 3.0E-130 T 28-03-2018 IPR010318 Protein of unknown function DUF917 CU254_RS26670 1ef92938cc59ccc320c1cbc0dc4af218 349 Pfam PF03060 Nitronate monooxygenase 8 334 4.1E-82 T 28-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CU254_RS26670 1ef92938cc59ccc320c1cbc0dc4af218 349 SUPERFAMILY SSF51412 4 342 2.29E-51 T 28-03-2018 CU254_RS26670 1ef92938cc59ccc320c1cbc0dc4af218 349 Gene3D G3DSA:3.20.20.70 4 347 4.4E-49 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS33315 4831a1840727db4c9ad80cd96015f032 521 Pfam PF01425 Amidase 54 499 1.8E-90 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS33315 4831a1840727db4c9ad80cd96015f032 521 SUPERFAMILY SSF75304 35 515 1.96E-106 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS33315 4831a1840727db4c9ad80cd96015f032 521 Gene3D G3DSA:3.90.1300.10 26 521 6.5E-134 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CU254_RS23785 f80713b3be3f3d10aa61d00a7e8e2375 359 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 184 329 3.0E-4 T 28-03-2018 CU254_RS23785 f80713b3be3f3d10aa61d00a7e8e2375 359 Pfam PF03601 Conserved hypothetical protein 698 19 335 1.9E-82 T 28-03-2018 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 CU254_RS18195 7aa6909815d3d261c1a67f8bdf7a8930 562 Pfam PF16450 Proteasomal ATPase OB/ID domain 65 200 8.8E-52 T 28-03-2018 IPR032501 Proteasomal ATPase, OB/ID domain CU254_RS18195 7aa6909815d3d261c1a67f8bdf7a8930 562 TIGRFAM TIGR03689 pup_AAA: proteasome ATPase 21 540 1.1E-255 T 28-03-2018 IPR022482 Proteasome ATPase GO:0000502|GO:0010498|GO:0016887|GO:0019941 CU254_RS18195 7aa6909815d3d261c1a67f8bdf7a8930 562 ProSitePatterns PS00674 AAA-protein family signature. 362 380 - T 28-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 CU254_RS18195 7aa6909815d3d261c1a67f8bdf7a8930 562 Gene3D G3DSA:3.40.50.300 182 408 3.9E-55 T 28-03-2018 CU254_RS18195 7aa6909815d3d261c1a67f8bdf7a8930 562 Gene3D G3DSA:1.20.5.340 1 118 3.0E-5 T 28-03-2018 CU254_RS18195 7aa6909815d3d261c1a67f8bdf7a8930 562 SMART SM00382 239 394 2.7E-22 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS18195 7aa6909815d3d261c1a67f8bdf7a8930 562 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 243 392 5.0E-48 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CU254_RS18195 7aa6909815d3d261c1a67f8bdf7a8930 562 SUPERFAMILY SSF52540 450 503 2.89E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS18195 7aa6909815d3d261c1a67f8bdf7a8930 562 SUPERFAMILY SSF52540 201 406 2.89E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS18195 7aa6909815d3d261c1a67f8bdf7a8930 562 Hamap MF_02112 Proteasome-associated ATPase [mpa]. 23 541 50.309 T 28-03-2018 IPR022482 Proteasome ATPase GO:0000502|GO:0010498|GO:0016887|GO:0019941 CU254_RS16370 20d77eed99caa1e876168e1cc094eeda 278 SUPERFAMILY SSF51569 7 275 5.57E-77 T 28-03-2018 CU254_RS16370 20d77eed99caa1e876168e1cc094eeda 278 Gene3D G3DSA:3.20.20.70 5 278 4.0E-83 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS16370 20d77eed99caa1e876168e1cc094eeda 278 Pfam PF01116 Fructose-bisphosphate aldolase class-II 9 276 1.3E-77 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CU254_RS16370 20d77eed99caa1e876168e1cc094eeda 278 PIRSF PIRSF001359 2 277 1.2E-68 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CU254_RS16370 20d77eed99caa1e876168e1cc094eeda 278 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 7 270 3.2E-65 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CU254_RS35400 9f81a510c21cf2e134de3a61faa61ef9 203 Gene3D G3DSA:3.60.160.10 2 203 2.4E-31 T 28-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 CU254_RS35400 9f81a510c21cf2e134de3a61faa61ef9 203 SUPERFAMILY SSF51219 1 198 3.14E-34 T 28-03-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain CU254_RS35400 9f81a510c21cf2e134de3a61faa61ef9 203 Pfam PF01987 Mitochondrial biogenesis AIM24 11 196 1.3E-29 T 28-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 CU254_RS18805 b12b459f857eccaef421c2908fc9b01c 328 Pfam PF02449 Beta-galactosidase 56 98 1.4E-4 T 28-03-2018 IPR013529 Glycoside hydrolase, family 42, N-terminal GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CU254_RS18805 b12b459f857eccaef421c2908fc9b01c 328 Gene3D G3DSA:3.20.20.80 52 320 3.9E-12 T 28-03-2018 CU254_RS18805 b12b459f857eccaef421c2908fc9b01c 328 SUPERFAMILY SSF51445 44 179 1.72E-13 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS18805 b12b459f857eccaef421c2908fc9b01c 328 SUPERFAMILY SSF51445 221 317 1.72E-13 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS09365 66b02eb5387d21d6920346254774a312 390 Gene3D G3DSA:3.40.630.10 2 280 2.6E-44 T 28-03-2018 CU254_RS09365 66b02eb5387d21d6920346254774a312 390 SUPERFAMILY SSF55031 182 292 4.34E-27 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CU254_RS09365 66b02eb5387d21d6920346254774a312 390 Pfam PF01546 Peptidase family M20/M25/M40 72 367 3.9E-19 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CU254_RS09365 66b02eb5387d21d6920346254774a312 390 Pfam PF07687 Peptidase dimerisation domain 185 282 3.5E-11 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CU254_RS09365 66b02eb5387d21d6920346254774a312 390 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 20 361 8.6E-66 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CU254_RS09365 66b02eb5387d21d6920346254774a312 390 SUPERFAMILY SSF53187 9 196 1.36E-42 T 28-03-2018 CU254_RS09365 66b02eb5387d21d6920346254774a312 390 SUPERFAMILY SSF53187 297 377 1.36E-42 T 28-03-2018 CU254_RS14505 3b8d858cd7511c55fad260e386aad8e3 416 Gene3D G3DSA:1.20.1250.20 218 414 1.1E-18 T 28-03-2018 CU254_RS14505 3b8d858cd7511c55fad260e386aad8e3 416 Gene3D G3DSA:1.20.1250.20 1 199 5.8E-31 T 28-03-2018 CU254_RS14505 3b8d858cd7511c55fad260e386aad8e3 416 Pfam PF07690 Major Facilitator Superfamily 4 371 2.1E-46 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS14505 3b8d858cd7511c55fad260e386aad8e3 416 SUPERFAMILY SSF103473 2 407 7.06E-72 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS23965 c6b0ab67f0c35245fda5cf05806e0243 523 SUPERFAMILY SSF56801 2 521 4.45E-144 T 28-03-2018 CU254_RS23965 c6b0ab67f0c35245fda5cf05806e0243 523 Gene3D G3DSA:3.40.50.980 1 188 3.2E-40 T 28-03-2018 CU254_RS23965 c6b0ab67f0c35245fda5cf05806e0243 523 ProSitePatterns PS00455 Putative AMP-binding domain signature. 183 194 - T 28-03-2018 IPR020845 AMP-binding, conserved site CU254_RS23965 c6b0ab67f0c35245fda5cf05806e0243 523 Gene3D G3DSA:2.30.38.10 341 424 3.6E-25 T 28-03-2018 CU254_RS23965 c6b0ab67f0c35245fda5cf05806e0243 523 Pfam PF13193 AMP-binding enzyme C-terminal domain 440 515 5.9E-21 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CU254_RS23965 c6b0ab67f0c35245fda5cf05806e0243 523 Gene3D G3DSA:3.40.50.980 189 340 7.2E-40 T 28-03-2018 CU254_RS23965 c6b0ab67f0c35245fda5cf05806e0243 523 Gene3D G3DSA:3.30.300.30 425 522 1.7E-28 T 28-03-2018 CU254_RS23965 c6b0ab67f0c35245fda5cf05806e0243 523 Pfam PF00501 AMP-binding enzyme 6 431 5.7E-96 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CU254_RS35825 48558bdbe816ea396e90451c0d1ea08d 202 Gene3D G3DSA:3.10.450.50 4 200 5.2E-31 T 28-03-2018 CU254_RS35825 48558bdbe816ea396e90451c0d1ea08d 202 Pfam PF13577 SnoaL-like domain 34 175 7.8E-23 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CU254_RS35825 48558bdbe816ea396e90451c0d1ea08d 202 SUPERFAMILY SSF54427 25 190 4.66E-30 T 28-03-2018 IPR032710 NTF2-like domain CU254_RS33960 5070fc86692022a5509e78c10ba05c2d 289 Gene3D G3DSA:2.30.320.10 10 289 1.9E-50 T 28-03-2018 CU254_RS33960 5070fc86692022a5509e78c10ba05c2d 289 Pfam PF09234 Domain of unknown function (DUF1963) 45 288 8.6E-33 T 28-03-2018 IPR015315 Protein of unknown function DUF1963 CU254_RS33960 5070fc86692022a5509e78c10ba05c2d 289 SUPERFAMILY SSF103032 44 288 6.8E-26 T 28-03-2018 IPR015315 Protein of unknown function DUF1963 CU254_RS12150 7fd33de2016e5fc8ccfbfdfc1f2399ae 304 Pfam PF05425 Copper resistance protein D 192 297 8.6E-15 T 28-03-2018 IPR008457 Copper resistance protein D GO:0016021 CU254_RS23345 7c164022761a8a94d0343b07ff8c8913 83 SUPERFAMILY SSF47336 5 80 7.2E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS23345 7c164022761a8a94d0343b07ff8c8913 83 Pfam PF00550 Phosphopantetheine attachment site 9 67 2.4E-9 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS23345 7c164022761a8a94d0343b07ff8c8913 83 Gene3D G3DSA:1.10.1200.10 2 82 3.6E-12 T 28-03-2018 CU254_RS31275 ba3bf176a22e809ca31302eb7af666c6 274 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 233 252 - T 28-03-2018 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CU254_RS31275 ba3bf176a22e809ca31302eb7af666c6 274 PRINTS PR00125 ATP synthase delta subunit signature 231 246 2.8E-10 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CU254_RS31275 ba3bf176a22e809ca31302eb7af666c6 274 PRINTS PR00125 ATP synthase delta subunit signature 246 264 2.8E-10 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CU254_RS31275 ba3bf176a22e809ca31302eb7af666c6 274 PRINTS PR00125 ATP synthase delta subunit signature 101 120 2.8E-10 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CU254_RS31275 ba3bf176a22e809ca31302eb7af666c6 274 Gene3D G3DSA:1.10.520.20 17 104 6.8E-7 T 28-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CU254_RS31275 ba3bf176a22e809ca31302eb7af666c6 274 Gene3D G3DSA:1.10.520.20 106 202 9.3E-16 T 28-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CU254_RS31275 ba3bf176a22e809ca31302eb7af666c6 274 Pfam PF00213 ATP synthase delta (OSCP) subunit 107 271 3.9E-34 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CU254_RS31275 ba3bf176a22e809ca31302eb7af666c6 274 Hamap MF_01416 ATP synthase subunit delta [atpD]. 97 273 14.223 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CU254_RS31275 ba3bf176a22e809ca31302eb7af666c6 274 SUPERFAMILY SSF47928 108 200 1.1E-5 T 28-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CU254_RS31275 ba3bf176a22e809ca31302eb7af666c6 274 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 106 271 3.0E-23 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CU254_RS38550 8b7fcd177af32efef783f2446ffb7a60 326 Pfam PF01032 FecCD transport family 15 317 2.2E-72 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CU254_RS38550 8b7fcd177af32efef783f2446ffb7a60 326 Gene3D G3DSA:1.10.3470.10 1 326 3.5E-60 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CU254_RS38550 8b7fcd177af32efef783f2446ffb7a60 326 SUPERFAMILY SSF81345 2 317 1.44E-61 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CU254_RS38905 38725a8cbdbd4d8b29d8bdb015ce1986 355 Gene3D G3DSA:3.30.420.40 215 268 4.2E-17 T 28-03-2018 CU254_RS38905 38725a8cbdbd4d8b29d8bdb015ce1986 355 SUPERFAMILY SSF53067 84 346 9.18E-39 T 28-03-2018 CU254_RS38905 38725a8cbdbd4d8b29d8bdb015ce1986 355 Pfam PF00480 ROK family 119 262 2.6E-28 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CU254_RS38905 38725a8cbdbd4d8b29d8bdb015ce1986 355 ProSitePatterns PS01125 ROK family signature. 214 241 - T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CU254_RS38905 38725a8cbdbd4d8b29d8bdb015ce1986 355 Gene3D G3DSA:3.30.420.40 73 214 3.0E-33 T 28-03-2018 CU254_RS38905 38725a8cbdbd4d8b29d8bdb015ce1986 355 SUPERFAMILY SSF46785 11 75 2.56E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS38905 38725a8cbdbd4d8b29d8bdb015ce1986 355 Gene3D G3DSA:3.30.420.40 269 354 6.2E-12 T 28-03-2018 CU254_RS38905 38725a8cbdbd4d8b29d8bdb015ce1986 355 Pfam PF12802 MarR family 16 66 4.8E-7 T 28-03-2018 CU254_RS38905 38725a8cbdbd4d8b29d8bdb015ce1986 355 Gene3D G3DSA:1.10.10.10 9 72 4.6E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS39435 45979dfa8ac0091248122e2609204856 241 Pfam PF01061 ABC-2 type transporter 2 198 7.0E-21 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CU254_RS15810 5d954912cd06e09eb5e55cc47c6af855 403 Pfam PF13439 Glycosyltransferase Family 4 22 197 2.8E-36 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CU254_RS15810 5d954912cd06e09eb5e55cc47c6af855 403 Gene3D G3DSA:3.40.50.2000 15 203 3.4E-30 T 28-03-2018 CU254_RS15810 5d954912cd06e09eb5e55cc47c6af855 403 Pfam PF00534 Glycosyl transferases group 1 208 370 1.4E-40 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CU254_RS15810 5d954912cd06e09eb5e55cc47c6af855 403 SUPERFAMILY SSF53756 1 391 1.57E-95 T 28-03-2018 CU254_RS15810 5d954912cd06e09eb5e55cc47c6af855 403 Gene3D G3DSA:3.40.50.2000 205 376 8.5E-52 T 28-03-2018 CU254_RS36490 b1964a7959cb2a0c3dd9ea4bd29a1d04 262 SUPERFAMILY SSF81301 9 81 3.52E-8 T 28-03-2018 CU254_RS36490 b1964a7959cb2a0c3dd9ea4bd29a1d04 262 Gene3D G3DSA:3.30.460.10 19 145 1.0E-13 T 28-03-2018 CU254_RS36490 b1964a7959cb2a0c3dd9ea4bd29a1d04 262 Pfam PF01909 Nucleotidyltransferase domain 26 108 1.3E-5 T 28-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 CU254_RS34995 591e86740306f8373dc1edc4e4c1f528 271 Pfam PF01061 ABC-2 type transporter 21 227 1.3E-23 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CU254_RS34995 591e86740306f8373dc1edc4e4c1f528 271 PIRSF PIRSF006648 17 267 1.6E-27 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CU254_RS22610 702a701dd9428f989279030159f82341 154 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 24 140 1.8E-6 T 28-03-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 CU254_RS22610 702a701dd9428f989279030159f82341 154 Gene3D G3DSA:3.30.530.20 2 154 4.4E-13 T 28-03-2018 IPR023393 START-like domain CU254_RS22610 702a701dd9428f989279030159f82341 154 SUPERFAMILY SSF55961 13 150 3.26E-15 T 28-03-2018 CU254_RS34555 7b45b6a17eb6e8b5310277c23162cfc2 380 Gene3D G3DSA:3.30.43.10 1 71 6.9E-13 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CU254_RS34555 7b45b6a17eb6e8b5310277c23162cfc2 380 Pfam PF01565 FAD binding domain 26 154 7.1E-25 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CU254_RS34555 7b45b6a17eb6e8b5310277c23162cfc2 380 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 26 59 - T 28-03-2018 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 CU254_RS34555 7b45b6a17eb6e8b5310277c23162cfc2 380 Gene3D G3DSA:3.30.465.10 72 176 4.2E-21 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CU254_RS34555 7b45b6a17eb6e8b5310277c23162cfc2 380 SUPERFAMILY SSF56176 5 174 7.48E-35 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CU254_RS19600 dac1ea651c797b45ec407313a44e815c 258 SUPERFAMILY SSF56281 3 246 6.68E-32 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS19600 dac1ea651c797b45ec407313a44e815c 258 SMART SM00849 48 239 1.2E-13 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS19600 dac1ea651c797b45ec407313a44e815c 258 Pfam PF00753 Metallo-beta-lactamase superfamily 53 226 2.3E-21 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS19600 dac1ea651c797b45ec407313a44e815c 258 Gene3D G3DSA:3.60.15.10 1 251 2.5E-40 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS02235 5ff5e1946e7d66a7732ed23b917b291c 620 Gene3D G3DSA:3.40.50.10490 248 465 1.2E-65 T 28-03-2018 CU254_RS02235 5ff5e1946e7d66a7732ed23b917b291c 620 SUPERFAMILY SSF53697 253 620 6.49E-105 T 28-03-2018 CU254_RS02235 5ff5e1946e7d66a7732ed23b917b291c 620 SUPERFAMILY SSF56235 2 243 2.49E-65 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CU254_RS02235 5ff5e1946e7d66a7732ed23b917b291c 620 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 620 40.511 T 28-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 CU254_RS02235 5ff5e1946e7d66a7732ed23b917b291c 620 Gene3D G3DSA:3.40.50.10490 466 618 4.6E-45 T 28-03-2018 CU254_RS02235 5ff5e1946e7d66a7732ed23b917b291c 620 Pfam PF13522 Glutamine amidotransferase domain 66 200 2.1E-20 T 28-03-2018 CU254_RS02235 5ff5e1946e7d66a7732ed23b917b291c 620 Pfam PF01380 SIS domain 297 421 1.9E-32 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CU254_RS02235 5ff5e1946e7d66a7732ed23b917b291c 620 Pfam PF01380 SIS domain 469 598 5.5E-20 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CU254_RS02235 5ff5e1946e7d66a7732ed23b917b291c 620 Gene3D G3DSA:3.60.20.10 2 247 1.6E-68 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CU254_RS02235 5ff5e1946e7d66a7732ed23b917b291c 620 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 620 3.7E-243 T 28-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 CU254_RS24065 2a43f8d4c41eccc9d433a855b34c3ff8 275 Pfam PF00005 ABC transporter 39 194 1.3E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS24065 2a43f8d4c41eccc9d433a855b34c3ff8 275 ProSitePatterns PS00211 ABC transporters family signature. 167 181 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS24065 2a43f8d4c41eccc9d433a855b34c3ff8 275 Gene3D G3DSA:3.40.50.300 21 273 2.5E-61 T 28-03-2018 CU254_RS24065 2a43f8d4c41eccc9d433a855b34c3ff8 275 SMART SM00382 48 263 2.5E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS24065 2a43f8d4c41eccc9d433a855b34c3ff8 275 SUPERFAMILY SSF52540 23 262 1.34E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS33125 63bfd91fbd4873bf26041ade75235433 323 Gene3D G3DSA:3.20.20.300 1 320 6.0E-64 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CU254_RS33125 63bfd91fbd4873bf26041ade75235433 323 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 6 315 2.2E-76 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CU254_RS33125 63bfd91fbd4873bf26041ade75235433 323 SUPERFAMILY SSF51445 49 318 2.32E-63 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS24835 467493047a6b92386ba90ef98faeb4fc 368 Pfam PF12146 Serine aminopeptidase, S33 40 156 6.2E-11 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 CU254_RS24835 467493047a6b92386ba90ef98faeb4fc 368 SUPERFAMILY SSF53474 291 361 3.98E-44 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS24835 467493047a6b92386ba90ef98faeb4fc 368 SUPERFAMILY SSF53474 13 156 3.98E-44 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS24835 467493047a6b92386ba90ef98faeb4fc 368 Gene3D G3DSA:3.40.50.1820 1 361 1.2E-39 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS00275 2e28cf39dccca42f7474313b1d4313cc 303 SUPERFAMILY SSF53850 95 289 7.06E-22 T 28-03-2018 CU254_RS00275 2e28cf39dccca42f7474313b1d4313cc 303 Gene3D G3DSA:3.40.190.10 91 180 2.5E-13 T 28-03-2018 CU254_RS00275 2e28cf39dccca42f7474313b1d4313cc 303 SUPERFAMILY SSF46785 6 117 1.85E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS00275 2e28cf39dccca42f7474313b1d4313cc 303 Pfam PF03466 LysR substrate binding domain 93 288 1.1E-24 T 28-03-2018 IPR005119 LysR, substrate-binding CU254_RS00275 2e28cf39dccca42f7474313b1d4313cc 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 1.1E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS00275 2e28cf39dccca42f7474313b1d4313cc 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 1.1E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS00275 2e28cf39dccca42f7474313b1d4313cc 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 1.1E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS00275 2e28cf39dccca42f7474313b1d4313cc 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 66 2.4E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS00275 2e28cf39dccca42f7474313b1d4313cc 303 Gene3D G3DSA:3.40.190.10 181 260 9.2E-7 T 28-03-2018 CU254_RS00275 2e28cf39dccca42f7474313b1d4313cc 303 Gene3D G3DSA:1.10.10.10 1 90 1.1E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS05035 e8dea2fbacbf606071e26a92fa23e2ac 159 Gene3D G3DSA:3.30.1310.10 2 98 5.9E-13 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CU254_RS07010 410d7e4e84841f4c6ff14ad4415a3696 207 Gene3D G3DSA:4.10.520.10 2 99 3.1E-25 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CU254_RS07010 410d7e4e84841f4c6ff14ad4415a3696 207 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 28-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 CU254_RS07010 410d7e4e84841f4c6ff14ad4415a3696 207 SMART SM00411 2 90 2.8E-31 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CU254_RS07010 410d7e4e84841f4c6ff14ad4415a3696 207 SUPERFAMILY SSF47729 3 93 8.24E-25 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CU254_RS07010 410d7e4e84841f4c6ff14ad4415a3696 207 Pfam PF00216 Bacterial DNA-binding protein 3 89 8.8E-25 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CU254_RS07010 410d7e4e84841f4c6ff14ad4415a3696 207 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 9.7E-14 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CU254_RS07010 410d7e4e84841f4c6ff14ad4415a3696 207 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 9.7E-14 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CU254_RS07010 410d7e4e84841f4c6ff14ad4415a3696 207 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 9.7E-14 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CU254_RS30890 f403374026789d2df4a482f1f49a73b2 354 Pfam PF01494 FAD binding domain 4 303 2.9E-20 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CU254_RS30890 f403374026789d2df4a482f1f49a73b2 354 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 142 157 2.0E-12 T 28-03-2018 CU254_RS30890 f403374026789d2df4a482f1f49a73b2 354 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 266 281 2.0E-12 T 28-03-2018 CU254_RS30890 f403374026789d2df4a482f1f49a73b2 354 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 2.0E-12 T 28-03-2018 CU254_RS30890 f403374026789d2df4a482f1f49a73b2 354 Gene3D G3DSA:3.50.50.60 2 332 2.1E-37 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS30890 f403374026789d2df4a482f1f49a73b2 354 SUPERFAMILY SSF51905 4 163 4.03E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS30890 f403374026789d2df4a482f1f49a73b2 354 SUPERFAMILY SSF51905 253 352 4.03E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS13075 03bc7ec34b143bb379ab3e4584b97f4f 478 Pfam PF13520 Amino acid permease 22 457 5.6E-54 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CU254_RS13075 03bc7ec34b143bb379ab3e4584b97f4f 478 PIRSF PIRSF006060 9 471 5.3E-76 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CU254_RS13075 03bc7ec34b143bb379ab3e4584b97f4f 478 Gene3D G3DSA:1.10.287.70 160 453 1.4E-4 T 28-03-2018 CU254_RS00860 91ec3592d31a06e712f4e99f3a62e326 432 Pfam PF04286 Protein of unknown function (DUF445) 68 430 3.3E-109 T 28-03-2018 IPR007383 Protein of unknown function DUF445 CU254_RS22820 f1403a07e877a01e8b1fbc513e72fbfc 402 PRINTS PR01047 Threonyl-tRNA synthetase signature 296 308 1.0E-42 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CU254_RS22820 f1403a07e877a01e8b1fbc513e72fbfc 402 PRINTS PR01047 Threonyl-tRNA synthetase signature 226 254 1.0E-42 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CU254_RS22820 f1403a07e877a01e8b1fbc513e72fbfc 402 PRINTS PR01047 Threonyl-tRNA synthetase signature 124 147 1.0E-42 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CU254_RS22820 f1403a07e877a01e8b1fbc513e72fbfc 402 PRINTS PR01047 Threonyl-tRNA synthetase signature 91 119 1.0E-42 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CU254_RS22820 f1403a07e877a01e8b1fbc513e72fbfc 402 PRINTS PR01047 Threonyl-tRNA synthetase signature 269 282 1.0E-42 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CU254_RS22820 f1403a07e877a01e8b1fbc513e72fbfc 402 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 86 290 5.7E-27 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CU254_RS22820 f1403a07e877a01e8b1fbc513e72fbfc 402 Gene3D G3DSA:3.30.930.10 1 288 1.5E-85 T 28-03-2018 CU254_RS22820 f1403a07e877a01e8b1fbc513e72fbfc 402 Gene3D G3DSA:3.40.50.800 289 399 1.2E-16 T 28-03-2018 IPR004154 Anticodon-binding CU254_RS22820 f1403a07e877a01e8b1fbc513e72fbfc 402 Pfam PF03129 Anticodon binding domain 303 390 2.9E-7 T 28-03-2018 IPR004154 Anticodon-binding CU254_RS22820 f1403a07e877a01e8b1fbc513e72fbfc 402 SUPERFAMILY SSF52954 291 395 2.72E-18 T 28-03-2018 IPR004154 Anticodon-binding CU254_RS22820 f1403a07e877a01e8b1fbc513e72fbfc 402 SUPERFAMILY SSF55681 3 288 1.32E-77 T 28-03-2018 CU254_RS22820 f1403a07e877a01e8b1fbc513e72fbfc 402 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 3 390 3.2E-124 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CU254_RS09065 0a71503dfcf0b2bfc25e385c3acf9fcd 260 Gene3D G3DSA:1.20.120.650 179 259 1.6E-16 T 28-03-2018 CU254_RS02315 dc148b8ae61aebc76d8515886decc4f6 197 Pfam PF12079 Protein of unknown function (DUF3558) 15 191 2.4E-27 T 28-03-2018 IPR024520 Protein of unknown function DUF3558 CU254_RS41555 440d2332555cf608c7b5988e8bfb336f 672 Gene3D G3DSA:1.10.10.10 476 596 2.2E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS41555 440d2332555cf608c7b5988e8bfb336f 672 Gene3D G3DSA:1.10.10.10 77 234 0.21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS41555 440d2332555cf608c7b5988e8bfb336f 672 SUPERFAMILY SSF46785 491 546 6.11E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS41555 440d2332555cf608c7b5988e8bfb336f 672 Gene3D G3DSA:1.10.10.10 363 475 0.0014 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS20770 02bd9923f3ad6bf1e384ddd6d8a215b2 383 SUPERFAMILY SSF52540 200 342 3.9E-32 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS20770 02bd9923f3ad6bf1e384ddd6d8a215b2 383 SUPERFAMILY SSF52540 58 132 3.9E-32 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS20770 02bd9923f3ad6bf1e384ddd6d8a215b2 383 Gene3D G3DSA:3.40.50.300 54 362 2.0E-35 T 28-03-2018 CU254_RS20770 02bd9923f3ad6bf1e384ddd6d8a215b2 383 Pfam PF13469 Sulfotransferase family 89 336 2.7E-60 T 28-03-2018 CU254_RS16905 7a1256239420bce5764e1768dccf2bb2 313 SUPERFAMILY SSF51556 6 310 1.11E-81 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS16905 7a1256239420bce5764e1768dccf2bb2 313 Pfam PF04909 Amidohydrolase 7 310 1.2E-39 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CU254_RS16905 7a1256239420bce5764e1768dccf2bb2 313 Gene3D G3DSA:3.20.20.140 6 313 5.6E-54 T 28-03-2018 CU254_RS30180 6022f68a85336f73c67d9f7069523131 81 Gene3D G3DSA:1.10.1200.10 8 78 8.5E-11 T 28-03-2018 CU254_RS30180 6022f68a85336f73c67d9f7069523131 81 SUPERFAMILY SSF47336 9 79 1.31E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS30180 6022f68a85336f73c67d9f7069523131 81 Pfam PF00550 Phosphopantetheine attachment site 20 70 1.2E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CU254_RS37315 b32ad9f746e08d4750749ccaa5b9bc4b 409 Pfam PF01546 Peptidase family M20/M25/M40 87 404 1.7E-28 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CU254_RS37315 b32ad9f746e08d4750749ccaa5b9bc4b 409 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 30 396 1.4E-97 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CU254_RS37315 b32ad9f746e08d4750749ccaa5b9bc4b 409 Gene3D G3DSA:3.40.630.10 13 247 4.9E-44 T 28-03-2018 CU254_RS37315 b32ad9f746e08d4750749ccaa5b9bc4b 409 Gene3D G3DSA:3.40.630.10 266 409 6.3E-21 T 28-03-2018 CU254_RS37315 b32ad9f746e08d4750749ccaa5b9bc4b 409 SUPERFAMILY SSF55031 201 314 2.62E-29 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CU254_RS37315 b32ad9f746e08d4750749ccaa5b9bc4b 409 PIRSF PIRSF005962 16 409 1.6E-111 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CU254_RS37315 b32ad9f746e08d4750749ccaa5b9bc4b 409 SUPERFAMILY SSF53187 316 408 2.69E-71 T 28-03-2018 CU254_RS37315 b32ad9f746e08d4750749ccaa5b9bc4b 409 SUPERFAMILY SSF53187 18 215 2.69E-71 T 28-03-2018 CU254_RS37315 b32ad9f746e08d4750749ccaa5b9bc4b 409 Pfam PF07687 Peptidase dimerisation domain 203 300 3.3E-12 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CU254_RS28990 5768d4e4654c3ff64d74589b85845553 238 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 90 237 1.6E-14 T 28-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 CU254_RS28990 5768d4e4654c3ff64d74589b85845553 238 SUPERFAMILY SSF48498 97 237 4.45E-24 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS28990 5768d4e4654c3ff64d74589b85845553 238 Gene3D G3DSA:1.10.357.10 90 238 4.9E-27 T 28-03-2018 CU254_RS28990 5768d4e4654c3ff64d74589b85845553 238 Pfam PF00440 Bacterial regulatory proteins, tetR family 35 76 1.7E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS28990 5768d4e4654c3ff64d74589b85845553 238 Gene3D G3DSA:1.10.10.60 17 89 2.2E-16 T 28-03-2018 CU254_RS28990 5768d4e4654c3ff64d74589b85845553 238 SUPERFAMILY SSF46689 22 87 2.15E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS25835 74fc4aa5feb2e84551ae024f49c20744 88 Pfam PF05800 Gas vesicle synthesis protein GvpO 7 87 4.0E-29 T 28-03-2018 IPR008634 Gas vesicle protein GvpO GO:0031412 CU254_RS25835 74fc4aa5feb2e84551ae024f49c20744 88 PIRSF PIRSF028743 2 88 4.4E-29 T 28-03-2018 IPR008634 Gas vesicle protein GvpO GO:0031412 CU254_RS23380 89304ea91cd12d4805f200315b26691b 1297 Pfam PF04183 IucA / IucC family 848 1091 1.2E-58 T 28-03-2018 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0015343|GO:0019290 CU254_RS23380 89304ea91cd12d4805f200315b26691b 1297 Pfam PF04183 IucA / IucC family 191 446 9.2E-58 T 28-03-2018 IPR007310 Aerobactin siderophore biosynthesis, IucA/IucC, N-terminal GO:0015343|GO:0019290 CU254_RS23380 89304ea91cd12d4805f200315b26691b 1297 Pfam PF06276 Ferric iron reductase FhuF-like transporter 1117 1279 1.4E-28 T 28-03-2018 IPR022770 Ferric iron reductase FhuF domain CU254_RS23380 89304ea91cd12d4805f200315b26691b 1297 Pfam PF06276 Ferric iron reductase FhuF-like transporter 477 641 4.5E-31 T 28-03-2018 IPR022770 Ferric iron reductase FhuF domain CU254_RS23380 89304ea91cd12d4805f200315b26691b 1297 Gene3D G3DSA:1.10.10.10 17 98 0.024 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS29330 64424d031396e59faf1a0bbfa00d649a 139 SUPERFAMILY SSF46785 7 134 1.89E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS29330 64424d031396e59faf1a0bbfa00d649a 139 Gene3D G3DSA:1.10.10.10 2 136 8.9E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS29330 64424d031396e59faf1a0bbfa00d649a 139 SMART SM00347 25 123 6.0E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS29330 64424d031396e59faf1a0bbfa00d649a 139 Pfam PF12802 MarR family 30 85 1.5E-9 T 28-03-2018 CU254_RS40020 5b35f28ffdd71979bb7003f309e100b4 266 Pfam PF10615 Protein of unknown function (DUF2470) 179 250 2.8E-8 T 28-03-2018 IPR019595 Domain of unknown function DUF2470 CU254_RS40020 5b35f28ffdd71979bb7003f309e100b4 266 SUPERFAMILY SSF50475 50 259 1.22E-19 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS40020 5b35f28ffdd71979bb7003f309e100b4 266 Gene3D G3DSA:3.20.180.10 166 255 1.5E-19 T 28-03-2018 IPR019595 Domain of unknown function DUF2470 CU254_RS16015 aa80bbfcc4a25e367cfe18a2c2a01a12 420 Pfam PF05977 Transmembrane secretion effector 9 392 3.1E-30 T 28-03-2018 IPR010290 Transmembrane secretion effector CU254_RS16015 aa80bbfcc4a25e367cfe18a2c2a01a12 420 Gene3D G3DSA:1.20.1250.20 205 417 3.1E-14 T 28-03-2018 CU254_RS16015 aa80bbfcc4a25e367cfe18a2c2a01a12 420 SUPERFAMILY SSF103473 7 392 1.44E-45 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS16015 aa80bbfcc4a25e367cfe18a2c2a01a12 420 Gene3D G3DSA:1.20.1250.20 3 198 6.8E-22 T 28-03-2018 CU254_RS40000 86b08456fca4875d55b314d556a12303 186 Gene3D G3DSA:1.20.1260.10 5 186 2.0E-45 T 28-03-2018 IPR012347 Ferritin-related CU254_RS40000 86b08456fca4875d55b314d556a12303 186 Pfam PF00210 Ferritin-like domain 17 150 7.5E-34 T 28-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 CU254_RS40000 86b08456fca4875d55b314d556a12303 186 SUPERFAMILY SSF47240 14 159 1.24E-44 T 28-03-2018 IPR009078 Ferritin-like superfamily CU254_RS24145 4c66c4bbdad2d221e845a477e41d8572 92 Pfam PF02426 Muconolactone delta-isomerase 1 89 6.1E-40 T 28-03-2018 IPR026029 Muconolactone isomerase domain KEGG: 00362+5.3.3.4|MetaCyc: PWY-6185 CU254_RS24145 4c66c4bbdad2d221e845a477e41d8572 92 ProDom PD006619 ISOMERASE MUCONOLACTONE DELTA-ISOMERASE HYDROCARBONS MIASE AROMATIC CATABOLISM METHYLMUCONOLACTONE DIRECT SEQUENCING 2 57 8.0E-19 T 28-03-2018 IPR003464 Muconolactone delta-isomerase GO:0006725 KEGG: 00362+5.3.3.4|MetaCyc: PWY-6185 CU254_RS24145 4c66c4bbdad2d221e845a477e41d8572 92 PIRSF PIRSF001486 1 92 6.1E-45 T 28-03-2018 IPR003464 Muconolactone delta-isomerase GO:0006725 KEGG: 00362+5.3.3.4|MetaCyc: PWY-6185 CU254_RS24145 4c66c4bbdad2d221e845a477e41d8572 92 TIGRFAM TIGR03221 muco_delta: muconolactone delta-isomerase 2 91 7.5E-46 T 28-03-2018 IPR003464 Muconolactone delta-isomerase GO:0006725 KEGG: 00362+5.3.3.4|MetaCyc: PWY-6185 CU254_RS24145 4c66c4bbdad2d221e845a477e41d8572 92 SUPERFAMILY SSF54909 1 91 1.41E-36 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS37670 219799992175b0999d3f37980759b2e8 136 SUPERFAMILY SSF50475 4 135 1.02E-18 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS37670 219799992175b0999d3f37980759b2e8 136 Gene3D G3DSA:2.30.110.10 1 131 2.1E-19 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS37670 219799992175b0999d3f37980759b2e8 136 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 4 121 2.2E-7 T 28-03-2018 IPR024747 Pyridoxamine 5'-phosphate oxidase-related CU254_RS12985 650fc1baf60921345cb5fcb95260c5dc 327 Pfam PF01032 FecCD transport family 15 321 4.4E-92 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CU254_RS12985 650fc1baf60921345cb5fcb95260c5dc 327 SUPERFAMILY SSF81345 6 321 9.15E-79 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CU254_RS12985 650fc1baf60921345cb5fcb95260c5dc 327 Gene3D G3DSA:1.10.3470.10 2 327 2.4E-67 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CU254_RS07030 a961fd27388b6c47988d1951d0782d2a 212 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 1.0E-13 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CU254_RS07030 a961fd27388b6c47988d1951d0782d2a 212 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 1.0E-13 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CU254_RS07030 a961fd27388b6c47988d1951d0782d2a 212 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 1.0E-13 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CU254_RS07030 a961fd27388b6c47988d1951d0782d2a 212 Gene3D G3DSA:4.10.520.10 2 99 9.8E-25 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CU254_RS07030 a961fd27388b6c47988d1951d0782d2a 212 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 28-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 CU254_RS07030 a961fd27388b6c47988d1951d0782d2a 212 Pfam PF00216 Bacterial DNA-binding protein 3 89 3.1E-24 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CU254_RS07030 a961fd27388b6c47988d1951d0782d2a 212 SMART SM00411 2 90 2.2E-31 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CU254_RS07030 a961fd27388b6c47988d1951d0782d2a 212 SUPERFAMILY SSF47729 3 93 4.71E-24 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CU254_RS19680 28e3e3bce659bc5dae300cf86796b315 200 SUPERFAMILY SSF46785 1 106 2.14E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS19680 28e3e3bce659bc5dae300cf86796b315 200 Gene3D G3DSA:1.10.10.10 5 170 1.6E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS19680 28e3e3bce659bc5dae300cf86796b315 200 Pfam PF12840 Helix-turn-helix domain 12 68 2.9E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS07875 36e619a9fd726f3fd058d1721a36dc56 108 Gene3D G3DSA:3.10.180.10 8 108 1.2E-7 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS07875 36e619a9fd726f3fd058d1721a36dc56 108 SUPERFAMILY SSF54593 5 105 9.2E-10 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS20785 1b541c7332ca281e1cfd44fcee476f32 259 SUPERFAMILY SSF52317 61 230 1.08E-14 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS20785 1b541c7332ca281e1cfd44fcee476f32 259 Pfam PF09825 Biotin-protein ligase, N terminal 44 139 3.5E-8 T 28-03-2018 IPR019197 Biotin-protein ligase, N-terminal Reactome: R-HSA-196780 CU254_RS20785 1b541c7332ca281e1cfd44fcee476f32 259 PIRSF PIRSF016642 30 240 1.4E-23 T 28-03-2018 IPR015834 Uncharacterised conserved protein UCP016642 CU254_RS20785 1b541c7332ca281e1cfd44fcee476f32 259 Gene3D G3DSA:3.40.50.880 41 249 5.0E-23 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS23645 5907971daf953acabd39998b87f92b73 113 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 8 109 7.5E-21 T 28-03-2018 CU254_RS19980 d678dfaaba0a280d7550c14ba6ad3580 140 Gene3D G3DSA:3.30.1330.40 20 140 2.6E-28 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CU254_RS19980 d678dfaaba0a280d7550c14ba6ad3580 140 SUPERFAMILY SSF55298 24 137 1.56E-30 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CU254_RS19980 d678dfaaba0a280d7550c14ba6ad3580 140 Pfam PF01042 Endoribonuclease L-PSP 26 134 2.0E-21 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family CU254_RS37320 b0cdca467b80c08b6538fc95a327c5cc 237 Gene3D G3DSA:3.40.50.150 5 235 1.3E-31 T 28-03-2018 CU254_RS37320 b0cdca467b80c08b6538fc95a327c5cc 237 SUPERFAMILY SSF53335 11 227 2.11E-34 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS37320 b0cdca467b80c08b6538fc95a327c5cc 237 Pfam PF13649 Methyltransferase domain 40 130 1.2E-17 T 28-03-2018 CU254_RS08055 1095664467b2b73b7e94bccd968483c1 248 Gene3D G3DSA:3.40.1160.10 5 241 3.0E-45 T 28-03-2018 CU254_RS08055 1095664467b2b73b7e94bccd968483c1 248 Pfam PF00696 Amino acid kinase family 12 219 1.5E-31 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CU254_RS08055 1095664467b2b73b7e94bccd968483c1 248 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 10 240 7.7E-87 T 28-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 CU254_RS08055 1095664467b2b73b7e94bccd968483c1 248 PIRSF PIRSF005650 6 248 9.5E-86 T 28-03-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 CU254_RS08055 1095664467b2b73b7e94bccd968483c1 248 SUPERFAMILY SSF53633 10 239 7.72E-71 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CU254_RS08055 1095664467b2b73b7e94bccd968483c1 248 Hamap MF_01220_B Uridylate kinase [pyrH]. 8 240 42.361 T 28-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 CU254_RS14320 fb0a6ef806ba07c5a55c9945c9e37ddc 230 Pfam PF08279 HTH domain 6 62 4.6E-9 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 CU254_RS14320 fb0a6ef806ba07c5a55c9945c9e37ddc 230 Gene3D G3DSA:1.10.10.10 1 68 3.0E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS14320 fb0a6ef806ba07c5a55c9945c9e37ddc 230 Pfam PF13280 WYL domain 141 225 1.7E-15 T 28-03-2018 IPR026881 WYL domain CU254_RS14320 fb0a6ef806ba07c5a55c9945c9e37ddc 230 SUPERFAMILY SSF46785 3 61 8.3E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS00150 1a47b71e5043cd773b498778d5a8542e 141 Gene3D G3DSA:3.30.450.30 7 134 8.8E-41 T 28-03-2018 CU254_RS00150 1a47b71e5043cd773b498778d5a8542e 141 SUPERFAMILY SSF103196 5 131 1.29E-34 T 28-03-2018 CU254_RS00150 1a47b71e5043cd773b498778d5a8542e 141 Pfam PF03259 Roadblock/LC7 domain 12 102 1.1E-23 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain CU254_RS00150 1a47b71e5043cd773b498778d5a8542e 141 SMART SM00960 12 102 9.8E-30 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain CU254_RS23280 95852324102703bba5612c7d4cd633f3 315 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 24 85 2.9E-8 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CU254_RS23280 95852324102703bba5612c7d4cd633f3 315 SUPERFAMILY SSF51735 109 270 3.27E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS23280 95852324102703bba5612c7d4cd633f3 315 Gene3D G3DSA:3.40.50.720 146 246 7.9E-20 T 28-03-2018 CU254_RS23280 95852324102703bba5612c7d4cd633f3 315 Pfam PF13602 Zinc-binding dehydrogenase 176 312 6.1E-15 T 28-03-2018 CU254_RS23280 95852324102703bba5612c7d4cd633f3 315 SUPERFAMILY SSF50129 4 141 7.91E-32 T 28-03-2018 IPR011032 GroES-like CU254_RS23280 95852324102703bba5612c7d4cd633f3 315 SMART SM00829 9 312 7.3E-14 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CU254_RS23280 95852324102703bba5612c7d4cd633f3 315 Gene3D G3DSA:3.90.180.10 1 145 2.8E-43 T 28-03-2018 CU254_RS23280 95852324102703bba5612c7d4cd633f3 315 Gene3D G3DSA:3.90.180.10 247 315 3.2E-5 T 28-03-2018 CU254_RS42315 91be0192d2285a0df588cfac31604163 249 Gene3D G3DSA:2.40.260.10 54 249 5.3E-13 T 28-03-2018 IPR023365 Sortase domain CU254_RS42315 91be0192d2285a0df588cfac31604163 249 SUPERFAMILY SSF63817 95 230 3.45E-6 T 28-03-2018 IPR023365 Sortase domain CU254_RS42315 91be0192d2285a0df588cfac31604163 249 Pfam PF04203 Sortase family 133 247 3.7E-7 T 28-03-2018 IPR005754 Sortase family CU254_RS15610 f50502c164f8ed566819921c9e8add82 123 Pfam PF01740 STAS domain 24 119 1.0E-10 T 28-03-2018 IPR002645 STAS domain CU254_RS15610 f50502c164f8ed566819921c9e8add82 123 Gene3D G3DSA:3.30.750.24 13 123 1.8E-16 T 28-03-2018 IPR002645 STAS domain CU254_RS15610 f50502c164f8ed566819921c9e8add82 123 SUPERFAMILY SSF52091 16 121 1.84E-19 T 28-03-2018 IPR002645 STAS domain CU254_RS15610 f50502c164f8ed566819921c9e8add82 123 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 17 118 5.0E-19 T 28-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 CU254_RS39835 3d1f8135d30cfc8e0cea38c10f577095 281 SMART SM00530 17 89 1.0E-4 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS39835 3d1f8135d30cfc8e0cea38c10f577095 281 Pfam PF13560 Helix-turn-helix domain 13 92 4.1E-17 T 28-03-2018 CU254_RS39835 3d1f8135d30cfc8e0cea38c10f577095 281 Gene3D G3DSA:1.10.260.40 5 107 1.8E-15 T 28-03-2018 CU254_RS39835 3d1f8135d30cfc8e0cea38c10f577095 281 SUPERFAMILY SSF47413 27 89 8.94E-7 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS06285 3a6cf3884cf973b48c94ef587e361d80 94 Pfam PF06243 Phenylacetic acid degradation B 4 90 1.0E-39 T 28-03-2018 IPR009359 Phenylacetic acid degradation B CU254_RS06285 3a6cf3884cf973b48c94ef587e361d80 94 TIGRFAM TIGR02157 PA_CoA_Oxy2: phenylacetate-CoA oxygenase, PaaH subunit 5 94 2.0E-48 T 28-03-2018 IPR009359 Phenylacetic acid degradation B CU254_RS06285 3a6cf3884cf973b48c94ef587e361d80 94 PIRSF PIRSF030200 1 94 8.5E-45 T 28-03-2018 IPR009359 Phenylacetic acid degradation B CU254_RS20865 d08133cc310e5b615c7ee8bb9d12896e 427 Gene3D G3DSA:3.40.190.10 22 191 5.4E-38 T 28-03-2018 CU254_RS20865 d08133cc310e5b615c7ee8bb9d12896e 427 SUPERFAMILY SSF53850 21 426 2.83E-69 T 28-03-2018 CU254_RS20865 d08133cc310e5b615c7ee8bb9d12896e 427 Gene3D G3DSA:3.40.190.10 192 368 1.8E-11 T 28-03-2018 CU254_RS20865 d08133cc310e5b615c7ee8bb9d12896e 427 Pfam PF01547 Bacterial extracellular solute-binding protein 51 337 1.2E-40 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 CU254_RS24550 2389a6a29be116339640fe43fae95d2d 147 Gene3D G3DSA:1.20.120.450 1 144 6.6E-20 T 28-03-2018 CU254_RS24550 2389a6a29be116339640fe43fae95d2d 147 Pfam PF04978 Protein of unknown function (DUF664) 8 138 4.9E-14 T 28-03-2018 IPR007061 Protein of unknown function DUF664 CU254_RS24550 2389a6a29be116339640fe43fae95d2d 147 SUPERFAMILY SSF109854 5 141 3.97E-20 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CU254_RS29190 8c08cab0ae9b5a72a463f00cc0e262d6 193 SUPERFAMILY SSF48498 82 186 1.56E-6 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS29190 8c08cab0ae9b5a72a463f00cc0e262d6 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 60 1.3E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS29190 8c08cab0ae9b5a72a463f00cc0e262d6 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 2.6E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS29190 8c08cab0ae9b5a72a463f00cc0e262d6 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 2.6E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS29190 8c08cab0ae9b5a72a463f00cc0e262d6 193 Gene3D G3DSA:1.10.357.10 1 192 5.4E-36 T 28-03-2018 CU254_RS29190 8c08cab0ae9b5a72a463f00cc0e262d6 193 SUPERFAMILY SSF46689 2 71 6.8E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS16645 d1dea98dd3e977ca3a9f96b2a84bbdae 145 Gene3D G3DSA:3.90.280.10 1 144 6.3E-25 T 28-03-2018 IPR008914 Phosphatidylethanolamine-binding protein CU254_RS16645 d1dea98dd3e977ca3a9f96b2a84bbdae 145 Pfam PF01161 Phosphatidylethanolamine-binding protein 17 144 1.3E-23 T 28-03-2018 IPR008914 Phosphatidylethanolamine-binding protein CU254_RS16645 d1dea98dd3e977ca3a9f96b2a84bbdae 145 SUPERFAMILY SSF49777 17 129 2.88E-24 T 28-03-2018 IPR008914 Phosphatidylethanolamine-binding protein CU254_RS16645 d1dea98dd3e977ca3a9f96b2a84bbdae 145 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 17 141 3.1E-20 T 28-03-2018 IPR005247 YbhB/YbcL CU254_RS33235 151ab4db1a6e53d9c2c6bdbdc8ba8300 343 Pfam PF04261 Dyp-type peroxidase family 12 308 2.4E-86 T 28-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 CU254_RS33235 151ab4db1a6e53d9c2c6bdbdc8ba8300 343 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 12 308 5.5E-79 T 28-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 CU254_RS33235 151ab4db1a6e53d9c2c6bdbdc8ba8300 343 SUPERFAMILY SSF54909 10 311 1.22E-94 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS41335 04f2660b358105e7eaa4158c92a13cf8 386 SUPERFAMILY SSF48452 214 347 2.92E-16 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS41335 04f2660b358105e7eaa4158c92a13cf8 386 Gene3D G3DSA:1.25.40.10 287 379 1.1E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS41335 04f2660b358105e7eaa4158c92a13cf8 386 Gene3D G3DSA:1.10.150.200 217 286 3.7E-6 T 28-03-2018 CU254_RS22105 616186d51b83c0db7a71080b38e3329b 724 Gene3D G3DSA:3.90.550.10 465 721 3.2E-23 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS22105 616186d51b83c0db7a71080b38e3329b 724 Pfam PF00535 Glycosyl transferase family 2 487 604 4.0E-16 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CU254_RS22105 616186d51b83c0db7a71080b38e3329b 724 SUPERFAMILY SSF53448 485 691 6.14E-29 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS22105 616186d51b83c0db7a71080b38e3329b 724 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 74 208 2.1E-6 T 28-03-2018 CU254_RS10290 acd43fac1aefe4cd1903a889b8a522a7 278 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 19 249 5.5E-81 T 28-03-2018 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted CU254_RS10290 acd43fac1aefe4cd1903a889b8a522a7 278 SUPERFAMILY SSF51679 20 270 3.53E-56 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS10290 acd43fac1aefe4cd1903a889b8a522a7 278 Gene3D G3DSA:3.20.20.30 19 234 3.3E-59 T 28-03-2018 CU254_RS10290 acd43fac1aefe4cd1903a889b8a522a7 278 Pfam PF00296 Luciferase-like monooxygenase 21 222 5.0E-48 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS03835 eeba6ffa6fba4f46ec57818ecc1c990f 439 Pfam PF01547 Bacterial extracellular solute-binding protein 74 336 6.9E-25 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 CU254_RS03835 eeba6ffa6fba4f46ec57818ecc1c990f 439 SUPERFAMILY SSF53850 40 410 7.85E-60 T 28-03-2018 CU254_RS03835 eeba6ffa6fba4f46ec57818ecc1c990f 439 Gene3D G3DSA:3.40.190.10 15 167 3.1E-19 T 28-03-2018 CU254_RS03835 eeba6ffa6fba4f46ec57818ecc1c990f 439 Gene3D G3DSA:3.40.190.10 168 359 1.5E-32 T 28-03-2018 CU254_RS03765 8c0a877102cacc5b64f0660094f9869a 222 Pfam PF13490 Putative zinc-finger 15 43 1.1E-5 T 28-03-2018 IPR027383 Putative zinc-finger CU254_RS10300 81d24f76db4fe72d75310405eb19b131 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 49 2.6E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS10300 81d24f76db4fe72d75310405eb19b131 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 57 80 2.6E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS10300 81d24f76db4fe72d75310405eb19b131 210 SUPERFAMILY SSF46689 30 94 5.99E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS10300 81d24f76db4fe72d75310405eb19b131 210 Gene3D G3DSA:1.10.357.10 32 210 6.8E-30 T 28-03-2018 CU254_RS10300 81d24f76db4fe72d75310405eb19b131 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 36 79 1.0E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS27455 d4ccdb3b1efd5cc9b07cdc5af2636e72 335 Gene3D G3DSA:3.40.190.10 85 217 2.0E-17 T 28-03-2018 CU254_RS27455 d4ccdb3b1efd5cc9b07cdc5af2636e72 335 SUPERFAMILY SSF53850 168 327 5.7E-19 T 28-03-2018 CU254_RS27455 d4ccdb3b1efd5cc9b07cdc5af2636e72 335 SUPERFAMILY SSF53850 6 137 5.7E-19 T 28-03-2018 CU254_RS41715 0ccf47621b4e8feb14b9d110301fdde2 417 Gene3D G3DSA:1.10.860.10 231 373 2.2E-13 T 28-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal CU254_RS41715 0ccf47621b4e8feb14b9d110301fdde2 417 Gene3D G3DSA:1.10.860.10 43 205 3.0E-25 T 28-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal CU254_RS41715 0ccf47621b4e8feb14b9d110301fdde2 417 Pfam PF00772 DnaB-like helicase N terminal domain 47 93 4.5E-10 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CU254_RS41715 0ccf47621b4e8feb14b9d110301fdde2 417 SUPERFAMILY SSF48024 47 96 6.41E-9 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CU254_RS12525 3e019b8068c890463b25613f4a1bd4bd 123 Gene3D G3DSA:3.10.180.10 11 123 6.8E-14 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS12525 3e019b8068c890463b25613f4a1bd4bd 123 SUPERFAMILY SSF54593 12 114 5.92E-17 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS23695 8cc3e83fecbad44c94410852bc9d0150 195 SUPERFAMILY SSF55469 1 195 1.03E-35 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CU254_RS23695 8cc3e83fecbad44c94410852bc9d0150 195 Gene3D G3DSA:3.40.109.10 1 193 3.3E-33 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CU254_RS23695 8cc3e83fecbad44c94410852bc9d0150 195 Pfam PF00881 Nitroreductase family 7 166 1.0E-17 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CU254_RS02780 170cbebc3627745ab166793b88caddf5 409 SUPERFAMILY SSF56601 94 332 1.57E-51 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CU254_RS02780 170cbebc3627745ab166793b88caddf5 409 SUPERFAMILY SSF56601 14 36 1.57E-51 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CU254_RS02780 170cbebc3627745ab166793b88caddf5 409 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 196 209 1.8E-7 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CU254_RS02780 170cbebc3627745ab166793b88caddf5 409 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 170 187 1.8E-7 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CU254_RS02780 170cbebc3627745ab166793b88caddf5 409 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 122 133 1.8E-7 T 28-03-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 CU254_RS02780 170cbebc3627745ab166793b88caddf5 409 Gene3D G3DSA:3.40.710.10 69 364 6.0E-49 T 28-03-2018 CU254_RS02780 170cbebc3627745ab166793b88caddf5 409 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 95 314 1.1E-34 T 28-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 CU254_RS24940 b85db6caf9ed332f8186b06d17e4053a 277 Pfam PF00756 Putative esterase 57 232 4.8E-11 T 28-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 CU254_RS24940 b85db6caf9ed332f8186b06d17e4053a 277 SUPERFAMILY SSF53474 45 274 3.44E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS24940 b85db6caf9ed332f8186b06d17e4053a 277 Gene3D G3DSA:3.40.50.1820 15 277 8.2E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS28160 05be1886d4d43b5ae7be04dcbf7eac01 98 Pfam PF03795 YCII-related domain 4 94 2.0E-6 T 28-03-2018 IPR005545 YCII-related CU254_RS28160 05be1886d4d43b5ae7be04dcbf7eac01 98 Gene3D G3DSA:3.30.70.1060 1 96 1.5E-12 T 28-03-2018 CU254_RS28160 05be1886d4d43b5ae7be04dcbf7eac01 98 SUPERFAMILY SSF54909 4 94 3.04E-9 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS15825 dc4c93ee4ca36b51935007afb9d34c92 289 Pfam PF04230 Polysaccharide pyruvyl transferase 184 222 5.4E-8 T 28-03-2018 IPR007345 Polysaccharide pyruvyl transferase CU254_RS33560 3f95a8764ffacdf3bf9070fb869df52f 297 Gene3D G3DSA:1.10.10.10 1 83 4.8E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS33560 3f95a8764ffacdf3bf9070fb869df52f 297 SUPERFAMILY SSF46785 1 84 3.37E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS33560 3f95a8764ffacdf3bf9070fb869df52f 297 SUPERFAMILY SSF53850 87 289 9.41E-32 T 28-03-2018 CU254_RS33560 3f95a8764ffacdf3bf9070fb869df52f 297 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 2.0E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS33560 3f95a8764ffacdf3bf9070fb869df52f 297 Pfam PF03466 LysR substrate binding domain 87 287 8.0E-37 T 28-03-2018 IPR005119 LysR, substrate-binding CU254_RS33560 3f95a8764ffacdf3bf9070fb869df52f 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.3E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS33560 3f95a8764ffacdf3bf9070fb869df52f 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.3E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS33560 3f95a8764ffacdf3bf9070fb869df52f 297 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.3E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS33560 3f95a8764ffacdf3bf9070fb869df52f 297 Gene3D G3DSA:3.40.190.10 88 180 1.3E-17 T 28-03-2018 CU254_RS33560 3f95a8764ffacdf3bf9070fb869df52f 297 Gene3D G3DSA:3.40.190.10 181 264 5.8E-20 T 28-03-2018 CU254_RS23660 90966c5f35684991ab8e48704ffc0b2e 127 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 1 110 1.0E-16 T 28-03-2018 IPR024412 Lsr2 CU254_RS23660 90966c5f35684991ab8e48704ffc0b2e 127 Pfam PF11774 Lsr2 1 108 2.3E-38 T 28-03-2018 IPR024412 Lsr2 CU254_RS33590 c98b1a06b3f5b11d11721900344485c6 160 SUPERFAMILY SSF54593 14 133 4.56E-19 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS33590 c98b1a06b3f5b11d11721900344485c6 160 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 16 131 1.2E-6 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CU254_RS33590 c98b1a06b3f5b11d11721900344485c6 160 Gene3D G3DSA:3.10.180.10 9 142 2.2E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS15670 0a05a199f8597a7ed724c1748069d219 184 Gene3D G3DSA:1.10.287.1060 74 174 9.5E-8 T 28-03-2018 CU254_RS15670 0a05a199f8597a7ed724c1748069d219 184 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 87 171 1.9E-6 T 28-03-2018 IPR022536 ESX-1 secretion-associated protein EspC GO:0009306 CU254_RS17970 6aaf1c6e56677640112014d05b04c977 386 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 42 373 3.0E-78 T 28-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 CU254_RS17970 6aaf1c6e56677640112014d05b04c977 386 SUPERFAMILY SSF54909 37 373 1.32E-80 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS17970 6aaf1c6e56677640112014d05b04c977 386 Pfam PF04261 Dyp-type peroxidase family 42 373 2.1E-89 T 28-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 CU254_RS09345 e13b0141b4c76cf81528a66dd9976b2a 219 SMART SM00701 40 194 6.8E-8 T 28-03-2018 IPR006619 Peptidoglycan recognition protein family domain, metazoa/bacteria GO:0008270|GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CU254_RS09345 e13b0141b4c76cf81528a66dd9976b2a 219 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 63 200 3.3E-19 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CU254_RS09345 e13b0141b4c76cf81528a66dd9976b2a 219 Gene3D G3DSA:3.40.80.10 32 218 4.2E-43 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CU254_RS09345 e13b0141b4c76cf81528a66dd9976b2a 219 SUPERFAMILY SSF55846 40 214 8.51E-45 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CU254_RS09345 e13b0141b4c76cf81528a66dd9976b2a 219 SMART SM00644 52 200 1.2E-4 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CU254_RS41460 863a1d13567461aa952e8a6c6be4893f 366 SUPERFAMILY SSF53474 46 346 1.41E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS41460 863a1d13567461aa952e8a6c6be4893f 366 Pfam PF12697 Alpha/beta hydrolase family 79 329 5.1E-12 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS41460 863a1d13567461aa952e8a6c6be4893f 366 Gene3D G3DSA:3.40.50.1820 36 345 3.0E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS35575 e626f283caee90730d04d8df5e37a95a 275 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 9 181 5.3E-25 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CU254_RS35575 e626f283caee90730d04d8df5e37a95a 275 Gene3D G3DSA:3.40.50.1110 4 194 2.3E-32 T 28-03-2018 CU254_RS35575 e626f283caee90730d04d8df5e37a95a 275 SUPERFAMILY SSF52266 6 190 5.0E-34 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CU254_RS35920 3ccfed50166d20cd40ff0e15238e0524 281 Gene3D G3DSA:3.40.50.150 8 92 1.4E-7 T 28-03-2018 CU254_RS35920 3ccfed50166d20cd40ff0e15238e0524 281 Pfam PF06259 Alpha/beta hydrolase 139 199 2.2E-11 T 28-03-2018 IPR010427 Protein of unknown function DUF1023 CU254_RS35920 3ccfed50166d20cd40ff0e15238e0524 281 SUPERFAMILY SSF53335 10 129 1.32E-14 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS35920 3ccfed50166d20cd40ff0e15238e0524 281 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 113 133 3.0E-5 T 28-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CU254_RS35920 3ccfed50166d20cd40ff0e15238e0524 281 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 15 35 3.0E-5 T 28-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CU254_RS35920 3ccfed50166d20cd40ff0e15238e0524 281 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 90 108 3.0E-5 T 28-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CU254_RS35920 3ccfed50166d20cd40ff0e15238e0524 281 Gene3D G3DSA:3.40.50.150 98 139 0.0072 T 28-03-2018 CU254_RS33615 a5addb3cc114026928f713ea7cf522c2 385 Pfam PF09375 Imelysin 149 378 9.0E-39 T 28-03-2018 IPR018976 Peptidase M75, Imelysin CU254_RS33615 a5addb3cc114026928f713ea7cf522c2 385 Pfam PF13473 Cupredoxin-like domain 19 132 2.7E-12 T 28-03-2018 IPR028096 EfeO-type cupredoxin-like domain CU254_RS01835 eeb7117fd97dafb4ae8756296d5393da 353 SUPERFAMILY SSF140453 105 182 3.27E-5 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CU254_RS01835 eeb7117fd97dafb4ae8756296d5393da 353 Gene3D G3DSA:1.10.287.1060 102 194 8.9E-9 T 28-03-2018 CU254_RS10965 2c97b9e5ecf03e770a969a1dbbe8da5c 482 PIRSF PIRSF002744 1 471 5.6E-94 T 28-03-2018 IPR026030 Purine-cytosine permease Fcy2/21/22 GO:0005215|GO:0016021|GO:0055085 CU254_RS10965 2c97b9e5ecf03e770a969a1dbbe8da5c 482 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 15 444 1.4E-54 T 28-03-2018 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 CU254_RS10965 2c97b9e5ecf03e770a969a1dbbe8da5c 482 ProSitePatterns PS01307 Flagellar motor protein motA family signature. 58 75 - T 28-03-2018 IPR000540 Flagellar motor protein MotA, conserved site CU254_RS38350 1cccaf14950c156bcba2f69a731a1a74 108 Pfam PF00893 Small Multidrug Resistance protein 4 95 5.3E-24 T 28-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 CU254_RS38350 1cccaf14950c156bcba2f69a731a1a74 108 SUPERFAMILY SSF103481 5 106 1.31E-16 T 28-03-2018 CU254_RS16380 02aed987c73ed7665dfbea75d4c6283e 319 Pfam PF13578 Methyltransferase domain 54 147 4.8E-8 T 28-03-2018 CU254_RS16380 02aed987c73ed7665dfbea75d4c6283e 319 Gene3D G3DSA:3.40.50.150 22 170 2.7E-5 T 28-03-2018 CU254_RS30290 418edc36d6267c17e6f8c3d69c09e94e 202 Gene3D G3DSA:1.10.10.60 1 60 9.7E-17 T 28-03-2018 CU254_RS30290 418edc36d6267c17e6f8c3d69c09e94e 202 SUPERFAMILY SSF46689 6 83 3.85E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS30290 418edc36d6267c17e6f8c3d69c09e94e 202 Gene3D G3DSA:1.10.357.10 61 202 3.3E-29 T 28-03-2018 CU254_RS30290 418edc36d6267c17e6f8c3d69c09e94e 202 ProSitePatterns PS01081 TetR-type HTH domain signature. 31 62 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CU254_RS30290 418edc36d6267c17e6f8c3d69c09e94e 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 60 2.6E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS04265 f411c791e59b84b22740080065d0b45e 380 SUPERFAMILY SSF53098 3 129 1.39E-30 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS04265 f411c791e59b84b22740080065d0b45e 380 SUPERFAMILY SSF53254 172 379 1.83E-55 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CU254_RS04265 f411c791e59b84b22740080065d0b45e 380 Pfam PF13456 Reverse transcriptase-like 9 130 8.2E-24 T 28-03-2018 CU254_RS04265 f411c791e59b84b22740080065d0b45e 380 PIRSF PIRSF036922 1 380 6.9E-169 T 28-03-2018 IPR014636 RNase H, phosphoglycerate mutase domain-containing CU254_RS04265 f411c791e59b84b22740080065d0b45e 380 Gene3D G3DSA:3.30.420.10 2 162 1.1E-31 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS04265 f411c791e59b84b22740080065d0b45e 380 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 175 374 3.8E-57 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CU254_RS04265 f411c791e59b84b22740080065d0b45e 380 SMART SM00855 174 335 1.0E-19 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CU254_RS04265 f411c791e59b84b22740080065d0b45e 380 Gene3D G3DSA:3.40.50.1240 168 380 7.9E-52 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CU254_RS19855 1b78a5f3d817326c7d0ce8754d4ec49f 268 SUPERFAMILY SSF47413 28 76 1.86E-9 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS19855 1b78a5f3d817326c7d0ce8754d4ec49f 268 Gene3D G3DSA:1.10.260.40 2 88 1.8E-16 T 28-03-2018 CU254_RS19855 1b78a5f3d817326c7d0ce8754d4ec49f 268 Pfam PF13560 Helix-turn-helix domain 5 83 1.3E-16 T 28-03-2018 CU254_RS19855 1b78a5f3d817326c7d0ce8754d4ec49f 268 SMART SM00530 8 78 6.2E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS06930 da8736c4f362629cf314d5c5a9ed013e 346 Hamap MF_01035 3-isopropylmalate dehydrogenase [leuB]. 1 338 57.071 T 28-03-2018 IPR023698 3-isopropylmalate dehydrogenase GO:0003862|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 CU254_RS06930 da8736c4f362629cf314d5c5a9ed013e 346 SUPERFAMILY SSF53659 2 323 2.69E-104 T 28-03-2018 CU254_RS06930 da8736c4f362629cf314d5c5a9ed013e 346 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 3 317 1.3E-84 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CU254_RS06930 da8736c4f362629cf314d5c5a9ed013e 346 SMART SM01329 2 334 3.8E-151 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CU254_RS06930 da8736c4f362629cf314d5c5a9ed013e 346 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 232 251 - T 28-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 CU254_RS06930 da8736c4f362629cf314d5c5a9ed013e 346 Gene3D G3DSA:3.40.718.10 1 339 7.4E-104 T 28-03-2018 CU254_RS06745 3fbc8bad5995dea7794ef6b953eb5118 398 Gene3D G3DSA:3.90.1150.10 267 385 3.2E-35 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS06745 3fbc8bad5995dea7794ef6b953eb5118 398 PIRSF PIRSF005572 1 384 6.3E-117 T 28-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CU254_RS06745 3fbc8bad5995dea7794ef6b953eb5118 398 Pfam PF00266 Aminotransferase class-V 3 370 2.8E-64 T 28-03-2018 IPR000192 Aminotransferase class V domain CU254_RS06745 3fbc8bad5995dea7794ef6b953eb5118 398 SUPERFAMILY SSF53383 1 378 1.73E-95 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS06745 3fbc8bad5995dea7794ef6b953eb5118 398 Gene3D G3DSA:3.40.640.10 13 259 7.7E-52 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS42040 d307ca04a81b4cdcc01fb4496af9e77a 407 Gene3D G3DSA:1.20.1250.20 1 203 1.5E-15 T 28-03-2018 CU254_RS42040 d307ca04a81b4cdcc01fb4496af9e77a 407 Pfam PF05977 Transmembrane secretion effector 2 391 5.3E-44 T 28-03-2018 IPR010290 Transmembrane secretion effector CU254_RS42040 d307ca04a81b4cdcc01fb4496af9e77a 407 SUPERFAMILY SSF103473 8 396 8.5E-43 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS42040 d307ca04a81b4cdcc01fb4496af9e77a 407 Gene3D G3DSA:1.20.1250.20 204 398 7.3E-18 T 28-03-2018 CU254_RS34795 dfb15ca3f86d5ad09bc18f6c05c73acf 392 Pfam PF12698 ABC-2 family transporter protein 27 370 3.7E-46 T 28-03-2018 CU254_RS13495 b7eb3fffc321ec1343cadd426792bc9c 199 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 95 180 3.5E-12 T 28-03-2018 CU254_RS13495 b7eb3fffc321ec1343cadd426792bc9c 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 4.4E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS13495 b7eb3fffc321ec1343cadd426792bc9c 199 Gene3D G3DSA:1.10.357.10 66 194 2.5E-26 T 28-03-2018 CU254_RS13495 b7eb3fffc321ec1343cadd426792bc9c 199 Gene3D G3DSA:1.10.260.40 44 65 2.1E-7 T 28-03-2018 CU254_RS13495 b7eb3fffc321ec1343cadd426792bc9c 199 SUPERFAMILY SSF48498 79 180 1.08E-20 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS13495 b7eb3fffc321ec1343cadd426792bc9c 199 Gene3D G3DSA:1.10.10.60 10 43 2.1E-14 T 28-03-2018 CU254_RS13495 b7eb3fffc321ec1343cadd426792bc9c 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 5.4E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS13495 b7eb3fffc321ec1343cadd426792bc9c 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 5.4E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS13495 b7eb3fffc321ec1343cadd426792bc9c 199 SUPERFAMILY SSF46689 7 72 1.64E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS03345 cf9cedee67398a84d66338d1be3fd0d6 312 Gene3D G3DSA:3.20.20.70 16 312 2.9E-101 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS03345 cf9cedee67398a84d66338d1be3fd0d6 312 Pfam PF00682 HMGL-like 20 291 1.6E-44 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CU254_RS03345 cf9cedee67398a84d66338d1be3fd0d6 312 SUPERFAMILY SSF51569 17 305 8.06E-67 T 28-03-2018 CU254_RS29695 366bf6643b6908799f580a4623b42b85 451 Pfam PF00144 Beta-lactamase 11 325 8.4E-66 T 28-03-2018 IPR001466 Beta-lactamase-related CU254_RS29695 366bf6643b6908799f580a4623b42b85 451 SUPERFAMILY SSF56601 6 338 5.78E-76 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CU254_RS29695 366bf6643b6908799f580a4623b42b85 451 Gene3D G3DSA:3.40.710.10 3 338 5.6E-76 T 28-03-2018 CU254_RS35025 c0a398ce49dbe4764297358c97642cb0 311 Gene3D G3DSA:3.40.1190.20 3 311 9.4E-63 T 28-03-2018 IPR029056 Ribokinase-like CU254_RS35025 c0a398ce49dbe4764297358c97642cb0 311 PRINTS PR00990 Ribokinase signature 220 231 2.1E-7 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CU254_RS35025 c0a398ce49dbe4764297358c97642cb0 311 PRINTS PR00990 Ribokinase signature 105 118 2.1E-7 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CU254_RS35025 c0a398ce49dbe4764297358c97642cb0 311 PRINTS PR00990 Ribokinase signature 8 29 2.1E-7 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CU254_RS35025 c0a398ce49dbe4764297358c97642cb0 311 PRINTS PR00990 Ribokinase signature 180 195 2.1E-7 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CU254_RS35025 c0a398ce49dbe4764297358c97642cb0 311 Pfam PF00294 pfkB family carbohydrate kinase 5 297 8.7E-45 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CU254_RS35025 c0a398ce49dbe4764297358c97642cb0 311 SUPERFAMILY SSF53613 4 297 3.43E-57 T 28-03-2018 IPR029056 Ribokinase-like CU254_RS30550 a737be4ed98f8b2ca8e184a36ae4b4b4 541 Pfam PF04185 Phosphoesterase family 54 497 2.4E-83 T 28-03-2018 IPR007312 Phosphoesterase GO:0016788 CU254_RS30550 a737be4ed98f8b2ca8e184a36ae4b4b4 541 Gene3D G3DSA:3.40.720.10 48 496 4.8E-10 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CU254_RS35415 fc5d07c104fecd61380d9580a4c44ccc 181 SUPERFAMILY SSF46785 4 87 4.29E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS35415 fc5d07c104fecd61380d9580a4c44ccc 181 SMART SM00418 7 102 2.1E-7 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS35415 fc5d07c104fecd61380d9580a4c44ccc 181 Pfam PF12840 Helix-turn-helix domain 7 61 7.0E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS35415 fc5d07c104fecd61380d9580a4c44ccc 181 Gene3D G3DSA:1.10.10.10 1 173 3.4E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS39740 f9e7fff626a060c3ffd6b2af0de9fb6b 342 Pfam PF05425 Copper resistance protein D 231 334 4.2E-19 T 28-03-2018 IPR008457 Copper resistance protein D GO:0016021 CU254_RS37195 e609638d4bd7deb525408fbeb858dfbf 209 Pfam PF03734 L,D-transpeptidase catalytic domain 104 207 4.3E-9 T 28-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CU254_RS37195 e609638d4bd7deb525408fbeb858dfbf 209 SUPERFAMILY SSF141523 99 207 7.19E-19 T 28-03-2018 CU254_RS37195 e609638d4bd7deb525408fbeb858dfbf 209 Gene3D G3DSA:2.40.440.10 93 208 6.6E-16 T 28-03-2018 CU254_RS39615 0325361284b3e4b50a944e2e80dd0ad0 272 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 268 3.1E-31 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS39615 0325361284b3e4b50a944e2e80dd0ad0 272 SUPERFAMILY SSF161098 63 250 4.97E-26 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS39615 0325361284b3e4b50a944e2e80dd0ad0 272 Gene3D G3DSA:1.10.3720.10 2 258 4.7E-43 T 28-03-2018 CU254_RS31225 3b7032ead2f5589aceb87e1e96b678dc 131 Gene3D G3DSA:3.10.450.50 2 129 8.1E-24 T 28-03-2018 CU254_RS31225 3b7032ead2f5589aceb87e1e96b678dc 131 SUPERFAMILY SSF54427 3 127 5.35E-32 T 28-03-2018 IPR032710 NTF2-like domain CU254_RS31225 3b7032ead2f5589aceb87e1e96b678dc 131 Pfam PF12680 SnoaL-like domain 5 112 1.9E-14 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CU254_RS10090 d46b2273617b8ecd4d2dbc98595039ac 162 Hamap MF_00977 3'-5' exoribonuclease. 1 159 43.236 T 28-03-2018 IPR030853 3-5 exoribonuclease, actinobacteria GO:0000287|GO:0008408 CU254_RS10090 d46b2273617b8ecd4d2dbc98595039ac 162 Pfam PF16473 3' exoribonuclease, RNase T-like 2 155 3.0E-19 T 28-03-2018 IPR033390 3'-5' exoribonuclease Rv2179c-like domain CU254_RS13190 61b5084056271fe3c1d5a2c41f7b17ad 272 Gene3D G3DSA:3.40.800.10 3 271 1.8E-39 T 28-03-2018 CU254_RS13190 61b5084056271fe3c1d5a2c41f7b17ad 272 Pfam PF00491 Arginase family 58 259 2.2E-23 T 28-03-2018 IPR006035 Ureohydrolase GO:0046872 CU254_RS13190 61b5084056271fe3c1d5a2c41f7b17ad 272 SUPERFAMILY SSF52768 8 262 2.34E-39 T 28-03-2018 CU254_RS10675 e6b0653fd8a2d924d061295f0cb89623 553 ProSitePatterns PS00163 Fumarate lyases signature. 461 470 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CU254_RS10675 e6b0653fd8a2d924d061295f0cb89623 553 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 378 541 1.4E-56 T 28-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CU254_RS10675 e6b0653fd8a2d924d061295f0cb89623 553 Pfam PF05681 Fumarate hydratase (Fumerase) 51 331 2.7E-81 T 28-03-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 CU254_RS10675 e6b0653fd8a2d924d061295f0cb89623 553 PIRSF PIRSF001394 31 551 3.7E-212 T 28-03-2018 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384 CU254_RS10675 e6b0653fd8a2d924d061295f0cb89623 553 SUPERFAMILY SSF117457 366 540 3.92E-60 T 28-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CU254_RS10675 e6b0653fd8a2d924d061295f0cb89623 553 Gene3D G3DSA:3.20.130.10 364 541 1.5E-66 T 28-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CU254_RS10675 e6b0653fd8a2d924d061295f0cb89623 553 Pfam PF05683 Fumarase C-terminus 337 542 5.6E-92 T 28-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CU254_RS24325 de9338c8dedf7e881f797906d50e99a1 67 Pfam PF14013 MT0933-like antitoxin protein 16 59 9.4E-10 T 28-03-2018 IPR028037 Antitoxin Rv0909/MT0933 CU254_RS16880 c3aeee14f917f1e629038d382039e42a 356 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 229 2.8E-18 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CU254_RS16880 c3aeee14f917f1e629038d382039e42a 356 SUPERFAMILY SSF51735 1 322 4.8E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS16880 c3aeee14f917f1e629038d382039e42a 356 Gene3D G3DSA:3.40.50.720 1 322 1.6E-35 T 28-03-2018 CU254_RS05705 7917ec5a224548c08969e43a1893edf2 178 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 51 152 2.2E-11 T 28-03-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 CU254_RS05705 7917ec5a224548c08969e43a1893edf2 178 SUPERFAMILY SSF55166 49 158 4.19E-22 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CU254_RS05705 7917ec5a224548c08969e43a1893edf2 178 Gene3D G3DSA:3.30.1380.10 47 154 3.3E-17 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CU254_RS38825 dfbb8a2451ce18abc549707f03b42315 600 SUPERFAMILY SSF55874 495 593 7.03E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS38825 dfbb8a2451ce18abc549707f03b42315 600 Pfam PF07730 Histidine kinase 388 452 2.7E-15 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CU254_RS38825 dfbb8a2451ce18abc549707f03b42315 600 Gene3D G3DSA:3.30.565.10 458 600 6.1E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS26945 46669af9cf6d805500064c8e79a8f4bd 444 SUPERFAMILY SSF103473 4 184 7.46E-49 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS26945 46669af9cf6d805500064c8e79a8f4bd 444 SUPERFAMILY SSF103473 231 437 7.46E-49 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS26945 46669af9cf6d805500064c8e79a8f4bd 444 Pfam PF07690 Major Facilitator Superfamily 3 390 5.5E-44 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS26945 46669af9cf6d805500064c8e79a8f4bd 444 Gene3D G3DSA:1.20.1250.20 1 189 3.8E-23 T 28-03-2018 CU254_RS26945 46669af9cf6d805500064c8e79a8f4bd 444 Gene3D G3DSA:1.20.1250.20 235 444 1.4E-18 T 28-03-2018 CU254_RS02355 cfa36e0d7eeb261e057cf93a5dc9a413 168 TIGRFAM TIGR04178 exo_archaeo: exosortase/archaeosortase family protein 63 156 3.5E-10 T 28-03-2018 IPR026392 Exosortase/Archaeosortase domain CU254_RS02495 a01996e9375fd8bdeb743b198aa83903 182 Pfam PF12079 Protein of unknown function (DUF3558) 17 175 7.1E-10 T 28-03-2018 IPR024520 Protein of unknown function DUF3558 CU254_RS02495 a01996e9375fd8bdeb743b198aa83903 182 Gene3D G3DSA:3.40.190.10 2 176 8.8E-4 T 28-03-2018 CU254_RS16070 3723cabc008a9a445ea61d0035f37ec6 282 Gene3D G3DSA:3.20.20.100 4 282 6.6E-58 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS16070 3723cabc008a9a445ea61d0035f37ec6 282 Pfam PF00248 Aldo/keto reductase family 18 281 1.5E-41 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS16070 3723cabc008a9a445ea61d0035f37ec6 282 PRINTS PR00069 Aldo-keto reductase signature 48 72 4.8E-5 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CU254_RS16070 3723cabc008a9a445ea61d0035f37ec6 282 PRINTS PR00069 Aldo-keto reductase signature 145 162 4.8E-5 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CU254_RS16070 3723cabc008a9a445ea61d0035f37ec6 282 PRINTS PR00069 Aldo-keto reductase signature 216 240 4.8E-5 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CU254_RS16070 3723cabc008a9a445ea61d0035f37ec6 282 SUPERFAMILY SSF51430 13 282 1.31E-58 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS34470 a948c5de71d02c6958d74f186cc64f47 512 TIGRFAM TIGR02677 TIGR02677: TIGR02677 family protein 9 500 3.2E-150 T 28-03-2018 IPR013493 Conserved hypothetical protein CHP02677 CU254_RS34470 a948c5de71d02c6958d74f186cc64f47 512 Pfam PF09660 Protein of unknown function (DUF2397) 11 493 5.9E-137 T 28-03-2018 IPR013493 Conserved hypothetical protein CHP02677 CU254_RS32165 efe2224e63a4533aad8d9a3990b36c60 375 Gene3D G3DSA:3.40.50.1820 36 375 9.1E-31 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS32165 efe2224e63a4533aad8d9a3990b36c60 375 Pfam PF00561 alpha/beta hydrolase fold 60 361 2.1E-30 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS32165 efe2224e63a4533aad8d9a3990b36c60 375 SUPERFAMILY SSF53474 30 374 6.15E-95 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS32165 efe2224e63a4533aad8d9a3990b36c60 375 TIGRFAM TIGR01392 homoserO_Ac_trn: homoserine O-acetyltransferase 32 373 3.1E-133 T 28-03-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 CU254_RS32165 efe2224e63a4533aad8d9a3990b36c60 375 Hamap MF_00296 Homoserine O-acetyltransferase [metX]. 7 375 43.689 T 28-03-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 CU254_RS32165 efe2224e63a4533aad8d9a3990b36c60 375 PIRSF PIRSF000443 21 375 2.5E-125 T 28-03-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 CU254_RS33765 901926607e729a198b6776e4abadce48 141 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 6 87 2.1E-8 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CU254_RS33765 901926607e729a198b6776e4abadce48 141 Gene3D G3DSA:2.30.110.10 1 136 3.3E-19 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS33765 901926607e729a198b6776e4abadce48 141 SUPERFAMILY SSF50475 2 138 4.3E-20 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS00980 4b422eab496b0ef2788b29405d3e83c4 265 Pfam PF09335 SNARE associated Golgi protein 38 161 9.1E-14 T 28-03-2018 IPR032816 SNARE associated Golgi protein CU254_RS41430 13cfe855713652ef415aff435ba6a3aa 484 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 425 434 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CU254_RS41430 13cfe855713652ef415aff435ba6a3aa 484 PRINTS PR00359 B-class P450 signature 400 415 3.0E-24 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS41430 13cfe855713652ef415aff435ba6a3aa 484 PRINTS PR00359 B-class P450 signature 224 240 3.0E-24 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS41430 13cfe855713652ef415aff435ba6a3aa 484 PRINTS PR00359 B-class P450 signature 241 256 3.0E-24 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS41430 13cfe855713652ef415aff435ba6a3aa 484 PRINTS PR00359 B-class P450 signature 423 432 3.0E-24 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS41430 13cfe855713652ef415aff435ba6a3aa 484 PRINTS PR00359 B-class P450 signature 372 399 3.0E-24 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS41430 13cfe855713652ef415aff435ba6a3aa 484 PRINTS PR00359 B-class P450 signature 178 189 3.0E-24 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS41430 13cfe855713652ef415aff435ba6a3aa 484 PRINTS PR00359 B-class P450 signature 432 443 3.0E-24 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS41430 13cfe855713652ef415aff435ba6a3aa 484 PRINTS PR00359 B-class P450 signature 355 366 3.0E-24 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS41430 13cfe855713652ef415aff435ba6a3aa 484 Pfam PF00067 Cytochrome P450 350 450 2.1E-16 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS41430 13cfe855713652ef415aff435ba6a3aa 484 Gene3D G3DSA:1.10.630.10 80 483 8.0E-49 T 28-03-2018 CU254_RS41430 13cfe855713652ef415aff435ba6a3aa 484 SUPERFAMILY SSF48264 102 481 1.19E-62 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS40165 30f791b290140780af1f16d2cc8af24b 150 Pfam PF03994 Domain of Unknown Function (DUF350) 25 78 2.3E-13 T 28-03-2018 IPR007140 Protein of unknown function DUF350 CU254_RS40165 30f791b290140780af1f16d2cc8af24b 150 Pfam PF03994 Domain of Unknown Function (DUF350) 95 149 3.2E-13 T 28-03-2018 IPR007140 Protein of unknown function DUF350 CU254_RS38250 a7195b6cb4eb45428cf67fb811ef2739 389 Gene3D G3DSA:3.30.420.10 227 389 3.1E-22 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS38250 a7195b6cb4eb45428cf67fb811ef2739 389 Gene3D G3DSA:1.10.10.60 61 93 3.4E-12 T 28-03-2018 CU254_RS38250 a7195b6cb4eb45428cf67fb811ef2739 389 SUPERFAMILY SSF46689 60 179 2.51E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS38250 a7195b6cb4eb45428cf67fb811ef2739 389 Gene3D G3DSA:1.10.260.40 94 148 2.9E-5 T 28-03-2018 CU254_RS38250 a7195b6cb4eb45428cf67fb811ef2739 389 Gene3D G3DSA:1.10.10.10 149 203 0.025 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS38250 a7195b6cb4eb45428cf67fb811ef2739 389 Pfam PF13936 Helix-turn-helix domain 61 103 1.5E-15 T 28-03-2018 IPR025246 Transposase IS30-like HTH domain CU254_RS38250 a7195b6cb4eb45428cf67fb811ef2739 389 Gene3D G3DSA:1.10.10.10 4 49 0.065 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS38250 a7195b6cb4eb45428cf67fb811ef2739 389 Pfam PF00665 Integrase core domain 235 342 3.7E-14 T 28-03-2018 IPR001584 Integrase, catalytic core GO:0015074 CU254_RS38250 a7195b6cb4eb45428cf67fb811ef2739 389 SUPERFAMILY SSF53098 235 381 2.43E-25 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS35650 3242cf03cc65bd32a007c3699bc11b30 138 Pfam PF06305 Lipopolysaccharide assembly protein A domain 86 137 3.2E-10 T 28-03-2018 IPR010445 Lipopolysaccharide assembly protein A domain GO:0005887 CU254_RS36165 1afc5e5997b16643b7a1088787266c1a 267 Pfam PF02146 Sir2 family 23 184 1.8E-20 T 28-03-2018 IPR003000 Sirtuin family GO:0070403 CU254_RS36165 1afc5e5997b16643b7a1088787266c1a 267 SUPERFAMILY SSF52467 3 266 2.76E-61 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CU254_RS36165 1afc5e5997b16643b7a1088787266c1a 267 Gene3D G3DSA:3.40.50.1220 1 266 6.0E-32 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CU254_RS10470 e8c3724245ad08e892fda30fd0e46b5a 188 Gene3D G3DSA:2.30.110.10 1 168 1.1E-46 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS10470 e8c3724245ad08e892fda30fd0e46b5a 188 SMART SM00903 17 167 3.5E-60 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CU254_RS10470 e8c3724245ad08e892fda30fd0e46b5a 188 SUPERFAMILY SSF50475 11 166 3.68E-47 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS10470 e8c3724245ad08e892fda30fd0e46b5a 188 Pfam PF01613 Flavin reductase like domain 18 166 5.7E-39 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CU254_RS20685 b0d60aa227321ef0558aef3d3225a0c8 270 Gene3D G3DSA:3.40.50.1820 2 269 2.4E-39 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS20685 b0d60aa227321ef0558aef3d3225a0c8 270 Pfam PF12697 Alpha/beta hydrolase family 21 257 9.6E-15 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS20685 b0d60aa227321ef0558aef3d3225a0c8 270 SUPERFAMILY SSF53474 8 263 6.97E-41 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS11825 c9b348f760d7afefedac1811452075f3 149 SUPERFAMILY SSF82649 2 141 3.92E-49 T 28-03-2018 CU254_RS11825 c9b348f760d7afefedac1811452075f3 149 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 3 139 1.3E-50 T 28-03-2018 CU254_RS11825 c9b348f760d7afefedac1811452075f3 149 Pfam PF01592 NifU-like N terminal domain 6 127 7.3E-31 T 28-03-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 CU254_RS11825 c9b348f760d7afefedac1811452075f3 149 Gene3D G3DSA:3.90.1010.10 1 140 7.8E-56 T 28-03-2018 CU254_RS36370 6da91f2231b7fa60540ce8c34bea36d0 830 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 639 661 5.5E-19 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CU254_RS36370 6da91f2231b7fa60540ce8c34bea36d0 830 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 711 725 5.5E-19 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CU254_RS36370 6da91f2231b7fa60540ce8c34bea36d0 830 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 477 496 5.5E-19 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CU254_RS36370 6da91f2231b7fa60540ce8c34bea36d0 830 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 696 710 5.5E-19 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CU254_RS36370 6da91f2231b7fa60540ce8c34bea36d0 830 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 631 822 2.9E-50 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CU254_RS36370 6da91f2231b7fa60540ce8c34bea36d0 830 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 454 611 5.7E-30 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CU254_RS36370 6da91f2231b7fa60540ce8c34bea36d0 830 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 620 807 1.0E-42 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CU254_RS36370 6da91f2231b7fa60540ce8c34bea36d0 830 Gene3D G3DSA:3.40.710.10 446 826 2.8E-38 T 28-03-2018 CU254_RS36370 6da91f2231b7fa60540ce8c34bea36d0 830 SUPERFAMILY SSF56601 450 812 3.81E-59 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CU254_RS38045 12de23e0bb90c6122e103fdff0d84e62 286 Gene3D G3DSA:1.20.1260.10 32 255 5.7E-8 T 28-03-2018 IPR012347 Ferritin-related CU254_RS38045 12de23e0bb90c6122e103fdff0d84e62 286 PIRSF PIRSF007580 1 283 5.9E-116 T 28-03-2018 IPR016516 Uncharacterised conserved protein UCP07580 CU254_RS38045 12de23e0bb90c6122e103fdff0d84e62 286 Pfam PF10118 Predicted metal-dependent hydrolase 11 263 2.7E-80 T 28-03-2018 IPR016516 Uncharacterised conserved protein UCP07580 CU254_RS26325 3fec3fd59c30044695b3dc15f8057d40 432 Pfam PF13286 Phosphohydrolase-associated domain 328 418 2.9E-21 T 28-03-2018 IPR026875 Phosphohydrolase-associated domain CU254_RS26325 3fec3fd59c30044695b3dc15f8057d40 432 TIGRFAM TIGR00277 HDIG: HDIG domain 73 109 1.4E-7 T 28-03-2018 IPR006675 HDIG domain CU254_RS26325 3fec3fd59c30044695b3dc15f8057d40 432 Gene3D G3DSA:1.10.3410.10 209 348 6.2E-27 T 28-03-2018 IPR023293 Deoxyguanosinetriphosphate triphosphohydrolase, central domain CU254_RS26325 3fec3fd59c30044695b3dc15f8057d40 432 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 31 418 8.8E-78 T 28-03-2018 IPR006261 dNTP triphosphohydrolase GO:0016793 CU254_RS26325 3fec3fd59c30044695b3dc15f8057d40 432 SUPERFAMILY SSF109604 29 238 2.24E-54 T 28-03-2018 CU254_RS26325 3fec3fd59c30044695b3dc15f8057d40 432 Pfam PF01966 HD domain 72 216 4.6E-19 T 28-03-2018 IPR006674 HD domain CU254_RS26325 3fec3fd59c30044695b3dc15f8057d40 432 SMART SM00471 68 227 3.2E-12 T 28-03-2018 IPR003607 HD/PDEase domain CU254_RS26325 3fec3fd59c30044695b3dc15f8057d40 432 Hamap MF_01212 Deoxyguanosinetriphosphate triphosphohydrolase-like protein. 5 421 30.869 T 28-03-2018 IPR023023 dNTP triphosphohydrolase, type 2 GO:0016793 CU254_RS26325 3fec3fd59c30044695b3dc15f8057d40 432 Gene3D G3DSA:1.10.3210.10 7 208 2.2E-59 T 28-03-2018 CU254_RS18380 f79e7b55d92c255e5c91246fe4211eeb 236 Pfam PF00106 short chain dehydrogenase 3 189 2.0E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18380 f79e7b55d92c255e5c91246fe4211eeb 236 SUPERFAMILY SSF51735 3 221 1.47E-60 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS18380 f79e7b55d92c255e5c91246fe4211eeb 236 Gene3D G3DSA:3.40.50.720 1 231 1.8E-57 T 28-03-2018 CU254_RS18380 f79e7b55d92c255e5c91246fe4211eeb 236 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 134 162 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS18380 f79e7b55d92c255e5c91246fe4211eeb 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 184 3.8E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18380 f79e7b55d92c255e5c91246fe4211eeb 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 3.8E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18380 f79e7b55d92c255e5c91246fe4211eeb 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 121 137 3.8E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18380 f79e7b55d92c255e5c91246fe4211eeb 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 3.8E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS18380 f79e7b55d92c255e5c91246fe4211eeb 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 3.8E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS41490 0727eea3e8a4a6a82bfbfc2ddd065f0f 194 SUPERFAMILY SSF48317 32 192 1.07E-8 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CU254_RS41490 0727eea3e8a4a6a82bfbfc2ddd065f0f 194 Gene3D G3DSA:1.20.144.10 103 193 5.1E-4 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CU254_RS17125 2d70e0db6edb70db40d82afa17a0817b 589 Pfam PF00920 Dehydratase family 82 582 6.3E-127 T 28-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CU254_RS17125 2d70e0db6edb70db40d82afa17a0817b 589 SUPERFAMILY SSF143975 18 385 1.31E-69 T 28-03-2018 CU254_RS17125 2d70e0db6edb70db40d82afa17a0817b 589 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 481 492 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CU254_RS17125 2d70e0db6edb70db40d82afa17a0817b 589 SUPERFAMILY SSF52016 386 583 9.42E-43 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CU254_RS03010 3d6840c8cf5c70459169f01634b9fa41 133 SMART SM00422 3 72 7.3E-21 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS03010 3d6840c8cf5c70459169f01634b9fa41 133 Gene3D G3DSA:1.10.1660.10 59 129 5.7E-13 T 28-03-2018 CU254_RS03010 3d6840c8cf5c70459169f01634b9fa41 133 SUPERFAMILY SSF46955 3 117 1.04E-29 T 28-03-2018 IPR009061 Putative DNA-binding domain CU254_RS03010 3d6840c8cf5c70459169f01634b9fa41 133 Pfam PF13411 MerR HTH family regulatory protein 3 69 6.2E-16 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS03010 3d6840c8cf5c70459169f01634b9fa41 133 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 28 1.4E-5 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS03010 3d6840c8cf5c70459169f01634b9fa41 133 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 4 15 1.4E-5 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS03010 3d6840c8cf5c70459169f01634b9fa41 133 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 1.4E-5 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CU254_RS03010 3d6840c8cf5c70459169f01634b9fa41 133 Gene3D G3DSA:1.10.1660.10 1 58 9.8E-20 T 28-03-2018 CU254_RS17185 c0f0bb641ff72642b553e003fe998d78 193 Gene3D G3DSA:1.10.10.10 131 192 7.7E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS17185 c0f0bb641ff72642b553e003fe998d78 193 Pfam PF04542 Sigma-70 region 2 40 103 1.1E-7 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS17185 c0f0bb641ff72642b553e003fe998d78 193 Pfam PF08281 Sigma-70, region 4 135 182 1.4E-10 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS17185 c0f0bb641ff72642b553e003fe998d78 193 SUPERFAMILY SSF88946 35 102 1.77E-10 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS17185 c0f0bb641ff72642b553e003fe998d78 193 Gene3D G3DSA:1.10.1740.10 33 108 6.3E-11 T 28-03-2018 CU254_RS17185 c0f0bb641ff72642b553e003fe998d78 193 SUPERFAMILY SSF88659 130 183 1.05E-10 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS17185 c0f0bb641ff72642b553e003fe998d78 193 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 37 184 1.4E-13 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CU254_RS17515 1204d328bd4cfe6059c9366f39e7fb44 427 Gene3D G3DSA:3.20.20.140 42 416 3.0E-55 T 28-03-2018 CU254_RS17515 1204d328bd4cfe6059c9366f39e7fb44 427 Pfam PF04909 Amidohydrolase 156 413 9.4E-28 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CU254_RS17515 1204d328bd4cfe6059c9366f39e7fb44 427 SUPERFAMILY SSF51556 46 74 2.16E-61 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS17515 1204d328bd4cfe6059c9366f39e7fb44 427 SUPERFAMILY SSF51556 116 413 2.16E-61 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS15675 a187c20fcbdb298ddf3477722e83f974 492 Gene3D G3DSA:1.20.1250.20 38 226 6.4E-27 T 28-03-2018 CU254_RS15675 a187c20fcbdb298ddf3477722e83f974 492 Gene3D G3DSA:1.20.1250.20 277 488 2.6E-20 T 28-03-2018 CU254_RS15675 a187c20fcbdb298ddf3477722e83f974 492 SUPERFAMILY SSF103473 25 218 8.24E-55 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS15675 a187c20fcbdb298ddf3477722e83f974 492 SUPERFAMILY SSF103473 273 483 8.24E-55 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS15675 a187c20fcbdb298ddf3477722e83f974 492 Pfam PF07690 Major Facilitator Superfamily 45 438 4.8E-43 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS38785 3f2a7fc3c9592673fc338394ed779915 311 Pfam PF00005 ABC transporter 17 156 7.4E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS38785 3f2a7fc3c9592673fc338394ed779915 311 Gene3D G3DSA:3.40.50.300 1 269 1.0E-56 T 28-03-2018 CU254_RS38785 3f2a7fc3c9592673fc338394ed779915 311 ProSitePatterns PS00211 ABC transporters family signature. 128 142 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS38785 3f2a7fc3c9592673fc338394ed779915 311 SUPERFAMILY SSF52540 2 225 7.64E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS38785 3f2a7fc3c9592673fc338394ed779915 311 SMART SM00382 26 204 2.4E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS12290 2563adec3533ea8d2c4342cea1ffb798 99 Gene3D G3DSA:3.30.1310.10 1 72 2.4E-12 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CU254_RS12290 2563adec3533ea8d2c4342cea1ffb798 99 SUPERFAMILY SSF82607 2 63 9.29E-5 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CU254_RS12290 2563adec3533ea8d2c4342cea1ffb798 99 Pfam PF02575 YbaB/EbfC DNA-binding family 2 64 8.1E-7 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CU254_RS23650 ba54f773c6fe8180af24dd97a0868c6b 593 Pfam PF00361 Proton-conducting membrane transporter 130 417 8.8E-54 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS11860 16e657489163a8c3fcc16ff4104374b1 399 Pfam PF07730 Histidine kinase 201 266 2.1E-17 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CU254_RS11860 16e657489163a8c3fcc16ff4104374b1 399 Gene3D G3DSA:3.30.565.10 273 399 1.7E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS11860 16e657489163a8c3fcc16ff4104374b1 399 SUPERFAMILY SSF55874 284 395 1.24E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS37855 69beac21949ce86fb8e1b481b9dacea1 193 Pfam PF13419 Haloacid dehalogenase-like hydrolase 85 179 2.9E-12 T 28-03-2018 IPR023214 HAD-like domain CU254_RS37855 69beac21949ce86fb8e1b481b9dacea1 193 SUPERFAMILY SSF56784 4 187 7.2E-30 T 28-03-2018 IPR023214 HAD-like domain CU254_RS37855 69beac21949ce86fb8e1b481b9dacea1 193 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 144 164 1.3E-10 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CU254_RS37855 69beac21949ce86fb8e1b481b9dacea1 193 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 1.3E-10 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CU254_RS37855 69beac21949ce86fb8e1b481b9dacea1 193 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 96 109 1.3E-10 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CU254_RS37855 69beac21949ce86fb8e1b481b9dacea1 193 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 126 142 1.3E-10 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CU254_RS37855 69beac21949ce86fb8e1b481b9dacea1 193 Gene3D G3DSA:3.40.50.1000 17 193 2.8E-22 T 28-03-2018 IPR023214 HAD-like domain CU254_RS37855 69beac21949ce86fb8e1b481b9dacea1 193 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 82 179 1.4E-16 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CU254_RS00870 3ec7b5f0889e6914ea480c963716b936 122 SUPERFAMILY SSF54593 5 121 2.48E-15 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS00870 3ec7b5f0889e6914ea480c963716b936 122 Gene3D G3DSA:3.10.180.10 2 122 9.0E-19 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS12280 4193c39bb47c619eb3329c06b5943ed0 260 Pfam PF01464 Transglycosylase SLT domain 22 90 1.9E-6 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 CU254_RS12280 4193c39bb47c619eb3329c06b5943ed0 260 SUPERFAMILY SSF53955 9 106 2.82E-12 T 28-03-2018 IPR023346 Lysozyme-like domain CU254_RS12280 4193c39bb47c619eb3329c06b5943ed0 260 Gene3D G3DSA:1.10.530.10 3 109 1.6E-6 T 28-03-2018 CU254_RS23720 50b4f9e498aa960382698fcaa199ce2f 324 TIGRFAM TIGR03945 PLP_SbnA_fam: 2,3-diaminopropionate biosynthesis protein SbnA 13 307 7.1E-115 T 28-03-2018 IPR023927 2,3-diaminopropionate biosynthesis protein SbnA CU254_RS23720 50b4f9e498aa960382698fcaa199ce2f 324 Gene3D G3DSA:3.40.50.1100 137 312 8.9E-35 T 28-03-2018 CU254_RS23720 50b4f9e498aa960382698fcaa199ce2f 324 Gene3D G3DSA:3.40.50.1100 20 136 1.1E-22 T 28-03-2018 CU254_RS23720 50b4f9e498aa960382698fcaa199ce2f 324 SUPERFAMILY SSF53686 23 308 1.17E-65 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CU254_RS23720 50b4f9e498aa960382698fcaa199ce2f 324 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 23 272 2.5E-44 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CU254_RS28005 6a69f40e5691a0f86ef22cf2be8813ff 343 Gene3D G3DSA:3.40.50.720 2 342 4.2E-33 T 28-03-2018 CU254_RS28005 6a69f40e5691a0f86ef22cf2be8813ff 343 SUPERFAMILY SSF51735 4 273 3.84E-28 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS28005 6a69f40e5691a0f86ef22cf2be8813ff 343 SUPERFAMILY SSF51735 307 336 3.84E-28 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS28005 6a69f40e5691a0f86ef22cf2be8813ff 343 Pfam PF01370 NAD dependent epimerase/dehydratase family 7 93 4.3E-5 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CU254_RS40435 36bdf89e88e1cb0735a8f096acab29ea 317 Pfam PF01061 ABC-2 type transporter 44 278 5.5E-23 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CU254_RS36345 260f6bd53e5aa43cf6a4a6f2435f00fc 473 SUPERFAMILY SSF140453 91 169 6.67E-5 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CU254_RS36345 260f6bd53e5aa43cf6a4a6f2435f00fc 473 Gene3D G3DSA:1.10.287.850 86 176 2.7E-8 T 28-03-2018 CU254_RS38640 a0750c8a173da0aec7fdcd69524d2356 444 Gene3D G3DSA:3.40.50.720 28 181 0.096 T 28-03-2018 CU254_RS38640 a0750c8a173da0aec7fdcd69524d2356 444 SUPERFAMILY SSF51735 200 441 5.8E-58 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS38640 a0750c8a173da0aec7fdcd69524d2356 444 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 205 381 5.9E-6 T 28-03-2018 CU254_RS38640 a0750c8a173da0aec7fdcd69524d2356 444 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 211 437 3.0E-45 T 28-03-2018 CU254_RS38640 a0750c8a173da0aec7fdcd69524d2356 444 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 337 365 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS38640 a0750c8a173da0aec7fdcd69524d2356 444 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 330 338 4.1E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS38640 a0750c8a173da0aec7fdcd69524d2356 444 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 277 288 4.1E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS38640 a0750c8a173da0aec7fdcd69524d2356 444 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 350 369 4.1E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS38640 a0750c8a173da0aec7fdcd69524d2356 444 Gene3D G3DSA:3.40.50.720 197 242 7.8E-11 T 28-03-2018 CU254_RS38640 a0750c8a173da0aec7fdcd69524d2356 444 Gene3D G3DSA:3.40.50.720 243 442 4.2E-45 T 28-03-2018 CU254_RS38640 a0750c8a173da0aec7fdcd69524d2356 444 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 277 288 6.4E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS38640 a0750c8a173da0aec7fdcd69524d2356 444 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 223 6.4E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS38640 a0750c8a173da0aec7fdcd69524d2356 444 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 350 369 6.4E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS38640 a0750c8a173da0aec7fdcd69524d2356 444 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 324 340 6.4E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS38640 a0750c8a173da0aec7fdcd69524d2356 444 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 371 388 6.4E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS38640 a0750c8a173da0aec7fdcd69524d2356 444 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 404 424 6.4E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS16785 e617e5c42c2ace3cb86acc3e37159ef8 170 Gene3D G3DSA:2.30.110.10 5 156 1.4E-33 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS16785 e617e5c42c2ace3cb86acc3e37159ef8 170 SUPERFAMILY SSF50475 9 148 2.06E-37 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS16785 e617e5c42c2ace3cb86acc3e37159ef8 170 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 14 99 2.1E-17 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CU254_RS16785 e617e5c42c2ace3cb86acc3e37159ef8 170 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 18 143 2.1E-28 T 28-03-2018 IPR019920 F420-binding domain, putative CU254_RS05075 b88d33dbcd58e8e264da1ebd4caf58ae 209 Gene3D G3DSA:1.20.144.10 10 206 0.012 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CU254_RS03480 f10a15d29d47d2e6fbd6a676cd9dc96d 511 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 227 397 1.6E-33 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CU254_RS03480 f10a15d29d47d2e6fbd6a676cd9dc96d 511 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 227 397 1.9E-41 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CU254_RS11255 d34cb8e54947db8768133ec2b0b2f4ff 696 Pfam PF00326 Prolyl oligopeptidase family 495 693 1.2E-48 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CU254_RS11255 d34cb8e54947db8768133ec2b0b2f4ff 696 SUPERFAMILY SSF82171 26 394 9.68E-37 T 28-03-2018 CU254_RS11255 d34cb8e54947db8768133ec2b0b2f4ff 696 Gene3D G3DSA:2.140.10.30 12 413 1.6E-56 T 28-03-2018 CU254_RS11255 d34cb8e54947db8768133ec2b0b2f4ff 696 Gene3D G3DSA:3.40.50.1820 414 696 3.4E-42 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS11255 d34cb8e54947db8768133ec2b0b2f4ff 696 Pfam PF00930 Dipeptidyl peptidase IV (DPP IV) N-terminal region 114 402 5.6E-39 T 28-03-2018 IPR002469 Dipeptidylpeptidase IV, N-terminal domain GO:0006508 CU254_RS11255 d34cb8e54947db8768133ec2b0b2f4ff 696 SUPERFAMILY SSF53474 444 692 5.99E-60 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS23905 da23c5fd9b63ff422950ec3bf4e90304 352 SUPERFAMILY SSF51412 2 259 2.14E-56 T 28-03-2018 CU254_RS23905 da23c5fd9b63ff422950ec3bf4e90304 352 SUPERFAMILY SSF51412 306 345 2.14E-56 T 28-03-2018 CU254_RS23905 da23c5fd9b63ff422950ec3bf4e90304 352 Pfam PF03060 Nitronate monooxygenase 5 337 3.6E-91 T 28-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CU254_RS23905 da23c5fd9b63ff422950ec3bf4e90304 352 Gene3D G3DSA:3.20.20.70 1 350 1.1E-57 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS41650 bcafa06d14a091b60305f85fd3d2b091 495 Gene3D G3DSA:3.40.50.300 99 477 8.8E-10 T 28-03-2018 CU254_RS41650 bcafa06d14a091b60305f85fd3d2b091 495 SUPERFAMILY SSF52540 55 425 1.58E-25 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS09270 54e702c4ac315e30cc40f2d28d2d8b3f 114 Gene3D G3DSA:3.30.70.100 1 98 1.3E-25 T 28-03-2018 CU254_RS09270 54e702c4ac315e30cc40f2d28d2d8b3f 114 SUPERFAMILY SSF54909 1 95 8.85E-22 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS09270 54e702c4ac315e30cc40f2d28d2d8b3f 114 Pfam PF07045 Domain of unknown function (DUF1330) 2 95 1.6E-23 T 28-03-2018 IPR010753 Domain of unknown function DUF1330 CU254_RS33575 2c33e6196e722535afad5672c2e529db 170 Pfam PF04417 Protein of unknown function (DUF501) 35 155 1.7E-36 T 28-03-2018 IPR007511 Protein of unknown function DUF501 CU254_RS17975 1ff7c96528a938b4dcb3bbf5bdbc8a0f 534 Pfam PF04185 Phosphoesterase family 49 494 1.2E-88 T 28-03-2018 IPR007312 Phosphoesterase GO:0016788 CU254_RS17975 1ff7c96528a938b4dcb3bbf5bdbc8a0f 534 Gene3D G3DSA:3.40.720.10 42 494 4.3E-11 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CU254_RS40325 bc4e67023b4ac5bb59dc0fb2a52153e3 172 Pfam PF01569 PAP2 superfamily 64 170 2.8E-15 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CU254_RS40325 bc4e67023b4ac5bb59dc0fb2a52153e3 172 SMART SM00014 61 165 2.7E-6 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CU254_RS40325 bc4e67023b4ac5bb59dc0fb2a52153e3 172 Gene3D G3DSA:1.20.144.10 8 172 1.8E-25 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CU254_RS40325 bc4e67023b4ac5bb59dc0fb2a52153e3 172 SUPERFAMILY SSF48317 24 166 5.49E-30 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CU254_RS26860 0c91ee03eb2d56e49db25096eef49d65 267 PIRSF PIRSF006648 18 266 4.0E-22 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CU254_RS26860 0c91ee03eb2d56e49db25096eef49d65 267 PRINTS PR00164 ABC-2 type transport system membrane protein signature 150 174 5.7E-9 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CU254_RS26860 0c91ee03eb2d56e49db25096eef49d65 267 PRINTS PR00164 ABC-2 type transport system membrane protein signature 35 56 5.7E-9 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CU254_RS26860 0c91ee03eb2d56e49db25096eef49d65 267 PRINTS PR00164 ABC-2 type transport system membrane protein signature 188 207 5.7E-9 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CU254_RS26860 0c91ee03eb2d56e49db25096eef49d65 267 PRINTS PR00164 ABC-2 type transport system membrane protein signature 208 227 5.7E-9 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CU254_RS26860 0c91ee03eb2d56e49db25096eef49d65 267 Pfam PF01061 ABC-2 type transporter 24 229 5.2E-20 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CU254_RS01460 c10899ed1dc3158c95d3ab7de85417e7 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 111 124 3.0E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS01460 c10899ed1dc3158c95d3ab7de85417e7 286 PRINTS PR00111 Alpha/beta hydrolase fold signature 50 65 3.0E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS01460 c10899ed1dc3158c95d3ab7de85417e7 286 SUPERFAMILY SSF53474 3 283 4.38E-73 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS01460 c10899ed1dc3158c95d3ab7de85417e7 286 Gene3D G3DSA:3.40.50.1820 1 286 2.3E-53 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS01460 c10899ed1dc3158c95d3ab7de85417e7 286 Pfam PF00561 alpha/beta hydrolase fold 25 267 5.5E-30 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS01460 c10899ed1dc3158c95d3ab7de85417e7 286 PRINTS PR00412 Epoxide hydrolase signature 31 49 1.9E-11 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS01460 c10899ed1dc3158c95d3ab7de85417e7 286 PRINTS PR00412 Epoxide hydrolase signature 111 124 1.9E-11 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS01460 c10899ed1dc3158c95d3ab7de85417e7 286 PRINTS PR00412 Epoxide hydrolase signature 97 110 1.9E-11 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS01460 c10899ed1dc3158c95d3ab7de85417e7 286 PRINTS PR00412 Epoxide hydrolase signature 258 280 1.9E-11 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS01460 c10899ed1dc3158c95d3ab7de85417e7 286 PRINTS PR00412 Epoxide hydrolase signature 226 242 1.9E-11 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS21940 4a5c157bf67936efe397b89542c4bd8c 186 SUPERFAMILY SSF52499 5 145 1.83E-43 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CU254_RS21940 4a5c157bf67936efe397b89542c4bd8c 186 Pfam PF00857 Isochorismatase family 10 140 3.5E-35 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CU254_RS21940 4a5c157bf67936efe397b89542c4bd8c 186 Gene3D G3DSA:3.40.50.850 2 183 1.1E-38 T 28-03-2018 CU254_RS01750 bb1d1683502463786bb87eed879d55da 184 ProSitePatterns PS01109 Ribosomal protein L10 signature. 6 40 - T 28-03-2018 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS01750 bb1d1683502463786bb87eed879d55da 184 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 1 158 24.802 T 28-03-2018 IPR022973 Ribosomal protein L10 CU254_RS01750 bb1d1683502463786bb87eed879d55da 184 Pfam PF00466 Ribosomal protein L10 1 98 7.9E-26 T 28-03-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 CU254_RS01750 bb1d1683502463786bb87eed879d55da 184 SUPERFAMILY SSF160369 1 168 1.03E-49 T 28-03-2018 CU254_RS18175 d456382eb8af9156fd39a188bf6970fc 384 SUPERFAMILY SSF54631 268 378 7.6E-7 T 28-03-2018 CU254_RS18175 d456382eb8af9156fd39a188bf6970fc 384 Gene3D G3DSA:3.10.580.10 255 383 7.5E-8 T 28-03-2018 CU254_RS18175 d456382eb8af9156fd39a188bf6970fc 384 Pfam PF13398 Peptidase M50B-like 76 163 1.3E-6 T 28-03-2018 CU254_RS18175 d456382eb8af9156fd39a188bf6970fc 384 PIRSF PIRSF006404 18 384 1.2E-67 T 28-03-2018 IPR016483 Uncharacterised conserved protein UCP006404, peptidase M50/CBS CU254_RS07625 2588a36e7963e31ab36200defe4b7a3d 351 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 11 204 7.0E-26 T 28-03-2018 CU254_RS07625 2588a36e7963e31ab36200defe4b7a3d 351 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 1.3E-9 T 28-03-2018 CU254_RS07625 2588a36e7963e31ab36200defe4b7a3d 351 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 279 295 1.3E-9 T 28-03-2018 CU254_RS07625 2588a36e7963e31ab36200defe4b7a3d 351 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 170 188 1.3E-9 T 28-03-2018 CU254_RS07625 2588a36e7963e31ab36200defe4b7a3d 351 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 129 137 1.0E-15 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CU254_RS07625 2588a36e7963e31ab36200defe4b7a3d 351 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 166 190 1.0E-15 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CU254_RS07625 2588a36e7963e31ab36200defe4b7a3d 351 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 9 31 1.0E-15 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CU254_RS07625 2588a36e7963e31ab36200defe4b7a3d 351 Gene3D G3DSA:3.50.50.60 7 153 1.4E-24 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS07625 2588a36e7963e31ab36200defe4b7a3d 351 SUPERFAMILY SSF51905 238 349 9.26E-38 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS07625 2588a36e7963e31ab36200defe4b7a3d 351 SUPERFAMILY SSF51905 9 201 9.26E-38 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS07625 2588a36e7963e31ab36200defe4b7a3d 351 Gene3D G3DSA:3.50.50.60 274 351 0.083 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS07625 2588a36e7963e31ab36200defe4b7a3d 351 Gene3D G3DSA:3.50.50.60 154 273 3.0E-17 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS08080 97243f671ee3b3c5f45677332bdd41d0 153 Pfam PF03551 Transcriptional regulator PadR-like family 5 73 3.3E-21 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CU254_RS08080 97243f671ee3b3c5f45677332bdd41d0 153 SUPERFAMILY SSF46785 2 95 1.12E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS08080 97243f671ee3b3c5f45677332bdd41d0 153 Gene3D G3DSA:1.10.10.10 1 98 5.6E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS32460 e07cadafe9f351e84cda5de1dc0e7876 225 SMART SM00448 3 113 2.6E-46 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS32460 e07cadafe9f351e84cda5de1dc0e7876 225 SUPERFAMILY SSF52172 3 179 6.83E-45 T 28-03-2018 IPR011006 CheY-like superfamily CU254_RS32460 e07cadafe9f351e84cda5de1dc0e7876 225 Gene3D G3DSA:3.40.50.2300 1 120 2.4E-38 T 28-03-2018 CU254_RS32460 e07cadafe9f351e84cda5de1dc0e7876 225 Gene3D G3DSA:1.10.10.10 121 225 6.6E-35 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS32460 e07cadafe9f351e84cda5de1dc0e7876 225 Pfam PF00072 Response regulator receiver domain 5 114 1.3E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CU254_RS32460 e07cadafe9f351e84cda5de1dc0e7876 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 221 6.4E-26 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS32460 e07cadafe9f351e84cda5de1dc0e7876 225 SMART SM00862 146 222 1.1E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS38635 78b659b9bd3072098b0f698aefcb929b 279 Gene3D G3DSA:3.10.129.10 27 162 1.8E-27 T 28-03-2018 CU254_RS38635 78b659b9bd3072098b0f698aefcb929b 279 Gene3D G3DSA:3.10.129.10 163 264 1.7E-16 T 28-03-2018 CU254_RS38635 78b659b9bd3072098b0f698aefcb929b 279 PRINTS PR01483 Fatty acid synthase signature 177 199 3.6E-6 T 28-03-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 CU254_RS38635 78b659b9bd3072098b0f698aefcb929b 279 PRINTS PR01483 Fatty acid synthase signature 199 220 3.6E-6 T 28-03-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 CU254_RS38635 78b659b9bd3072098b0f698aefcb929b 279 SUPERFAMILY SSF54637 170 277 3.16E-24 T 28-03-2018 IPR029069 HotDog domain CU254_RS38635 78b659b9bd3072098b0f698aefcb929b 279 Pfam PF01575 MaoC like domain 181 257 5.3E-16 T 28-03-2018 IPR002539 MaoC-like domain CU254_RS38635 78b659b9bd3072098b0f698aefcb929b 279 SUPERFAMILY SSF54637 40 158 3.02E-11 T 28-03-2018 IPR029069 HotDog domain CU254_RS20200 5f6b2f57990ce00178be66b31016996c 199 Pfam PF06042 Nucleotidyltransferase 31 194 3.5E-55 T 28-03-2018 IPR009267 Putative nucleotidyltransferase CU254_RS31350 10113fdced025892cb05f1e6b4a74639 475 ProDom PD141294 TRANSMEMBRANE MEMBRANE PROTEIN GTRIV-SF YFDI PREDICTED 250 436 2.0E-4 T 28-03-2018 CU254_RS05790 42dfdc144275c97f66118915ecac3398 202 Pfam PF02517 CAAX protease self-immunity 102 180 6.0E-7 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CU254_RS07810 c985428cd48b2b699b0015d2b983104b 228 Pfam PF06197 Protein of unknown function (DUF998) 33 221 9.5E-18 T 28-03-2018 IPR009339 Protein of unknown function DUF998 CU254_RS37980 cb04545b50f1c664201bf1cb391c1204 297 SUPERFAMILY SSF47413 9 67 3.22E-9 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS37980 cb04545b50f1c664201bf1cb391c1204 297 Gene3D G3DSA:1.10.260.40 5 97 4.5E-11 T 28-03-2018 CU254_RS37980 cb04545b50f1c664201bf1cb391c1204 297 SMART SM00530 17 72 1.4E-4 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS37980 cb04545b50f1c664201bf1cb391c1204 297 Pfam PF12844 Helix-turn-helix domain 15 67 2.8E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS26840 c72970909927991ba486f8b2d4deada1 104 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 3 104 22.232 T 28-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS26840 c72970909927991ba486f8b2d4deada1 104 SUPERFAMILY SSF141091 4 102 1.15E-32 T 28-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS26840 c72970909927991ba486f8b2d4deada1 104 Pfam PF00829 Ribosomal prokaryotic L21 protein 4 102 1.1E-34 T 28-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS26840 c72970909927991ba486f8b2d4deada1 104 TIGRFAM TIGR00061 L21: ribosomal protein bL21 4 102 1.9E-26 T 28-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS26840 c72970909927991ba486f8b2d4deada1 104 ProSitePatterns PS01169 Ribosomal protein L21 signature. 73 95 - T 28-03-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS18785 878d4c40044426b442051e6dafbb5503 325 Pfam PF16363 GDP-mannose 4,6 dehydratase 10 307 1.6E-59 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS18785 878d4c40044426b442051e6dafbb5503 325 Gene3D G3DSA:3.90.25.10 178 324 5.3E-35 T 28-03-2018 CU254_RS18785 878d4c40044426b442051e6dafbb5503 325 SUPERFAMILY SSF51735 2 317 7.86E-90 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS18785 878d4c40044426b442051e6dafbb5503 325 Gene3D G3DSA:3.40.50.720 1 177 5.2E-46 T 28-03-2018 CU254_RS29010 100f6650e5991b536fcca6b2188c12e1 158 Gene3D G3DSA:1.20.120.540 10 128 2.5E-16 T 28-03-2018 IPR027378 Cyclic nucleotide-regulated ion channel, N-terminal domain Reactome: R-HSA-159418|Reactome: R-HSA-879518 CU254_RS29010 100f6650e5991b536fcca6b2188c12e1 158 Pfam PF07690 Major Facilitator Superfamily 21 131 1.9E-13 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS29010 100f6650e5991b536fcca6b2188c12e1 158 SUPERFAMILY SSF103473 7 131 6.54E-20 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS15210 c96ecaeaed8698a242930e095893653d 280 Pfam PF08223 PaaX-like protein C-terminal domain 180 270 2.0E-13 T 28-03-2018 IPR013225 PaaX-like, C-terminal CU254_RS15210 c96ecaeaed8698a242930e095893653d 280 Pfam PF07848 PaaX-like protein 15 81 9.8E-14 T 28-03-2018 IPR012906 PaaX-like, N-terminal CU254_RS15210 c96ecaeaed8698a242930e095893653d 280 PIRSF PIRSF020623 8 279 6.7E-47 T 28-03-2018 IPR011965 Phenylacetic acid degradation operon negative regulatory protein PaaX GO:0006351 CU254_RS15210 c96ecaeaed8698a242930e095893653d 280 Gene3D G3DSA:1.10.10.10 12 94 7.3E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS05180 092f46edccb7fb2cd1479281e8925757 263 Pfam PF12706 Beta-lactamase superfamily domain 24 207 1.6E-30 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS05180 092f46edccb7fb2cd1479281e8925757 263 Gene3D G3DSA:3.60.15.10 2 262 2.3E-34 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS05180 092f46edccb7fb2cd1479281e8925757 263 SUPERFAMILY SSF56281 6 211 2.1E-25 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS23500 d9b48fec313b6d4d97a32e7aaf1487a3 271 SUPERFAMILY SSF51735 1 241 5.0E-50 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS23500 d9b48fec313b6d4d97a32e7aaf1487a3 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 2.3E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23500 d9b48fec313b6d4d97a32e7aaf1487a3 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 2.3E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23500 d9b48fec313b6d4d97a32e7aaf1487a3 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 2.3E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23500 d9b48fec313b6d4d97a32e7aaf1487a3 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 182 2.3E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23500 d9b48fec313b6d4d97a32e7aaf1487a3 271 Pfam PF00106 short chain dehydrogenase 6 202 1.2E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23500 d9b48fec313b6d4d97a32e7aaf1487a3 271 Gene3D G3DSA:3.40.50.720 1 269 1.6E-54 T 28-03-2018 CU254_RS01015 03ffa9f13bf639e3c3f3684ed0c49714 170 SUPERFAMILY SSF69635 4 128 1.73E-28 T 28-03-2018 CU254_RS01015 03ffa9f13bf639e3c3f3684ed0c49714 170 Pfam PF10722 Putative bacterial sensory transduction regulator 5 123 2.5E-22 T 28-03-2018 IPR019660 Putative sensory transduction regulator YbjN CU254_RS01015 03ffa9f13bf639e3c3f3684ed0c49714 170 Gene3D G3DSA:3.30.1460.10 2 136 3.4E-38 T 28-03-2018 CU254_RS09785 4d8ca2d19000bc41142e870d29c87c0c 170 Pfam PF16157 Domain of unknown function (DUF4865) 2 162 2.5E-49 T 28-03-2018 IPR032349 Protein of unknown function DUF4865 CU254_RS11010 cc6c31b99062d3f0f6bd5b09292e3e74 95 Gene3D G3DSA:3.40.1620.10 3 82 4.6E-14 T 28-03-2018 CU254_RS11010 cc6c31b99062d3f0f6bd5b09292e3e74 95 SUPERFAMILY SSF143120 5 46 5.75E-8 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CU254_RS11010 cc6c31b99062d3f0f6bd5b09292e3e74 95 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 5 43 2.1E-7 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CU254_RS11010 cc6c31b99062d3f0f6bd5b09292e3e74 95 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 7 41 1.4E-8 T 28-03-2018 CU254_RS15580 50a4bd02a8a9a7d6911c46438ba9251d 154 Pfam PF04978 Protein of unknown function (DUF664) 20 150 1.2E-30 T 28-03-2018 IPR007061 Protein of unknown function DUF664 CU254_RS15580 50a4bd02a8a9a7d6911c46438ba9251d 154 Gene3D G3DSA:1.20.120.450 2 154 1.7E-28 T 28-03-2018 CU254_RS15580 50a4bd02a8a9a7d6911c46438ba9251d 154 SUPERFAMILY SSF109854 6 149 4.73E-34 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CU254_RS06150 141e86478af752fb6b5eb500282e4263 294 Gene3D G3DSA:1.10.3720.10 38 288 1.4E-26 T 28-03-2018 CU254_RS06150 141e86478af752fb6b5eb500282e4263 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 110 274 1.7E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS06150 141e86478af752fb6b5eb500282e4263 294 SUPERFAMILY SSF161098 86 274 1.07E-28 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS26340 e278b86647aad39dcf290d881441150a 409 SUPERFAMILY SSF55874 292 389 1.51E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS26340 e278b86647aad39dcf290d881441150a 409 Pfam PF07730 Histidine kinase 207 275 3.4E-16 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CU254_RS26340 e278b86647aad39dcf290d881441150a 409 Gene3D G3DSA:3.30.565.10 274 390 1.6E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS37950 7ec370afb64a66e8ce73938c3ba4cb6a 199 Pfam PF07510 Protein of unknown function (DUF1524) 97 194 6.2E-8 T 28-03-2018 IPR011089 Domain of unknown function DUF1524 CU254_RS32670 0d2be4ea2ce92cc5375890a12fa68299 321 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 189 199 1.1E-13 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CU254_RS32670 0d2be4ea2ce92cc5375890a12fa68299 321 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 13 29 1.1E-13 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CU254_RS32670 0d2be4ea2ce92cc5375890a12fa68299 321 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 62 81 1.1E-13 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CU254_RS32670 0d2be4ea2ce92cc5375890a12fa68299 321 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 136 157 1.1E-13 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CU254_RS32670 0d2be4ea2ce92cc5375890a12fa68299 321 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 4 318 1.0E-71 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CU254_RS32670 0d2be4ea2ce92cc5375890a12fa68299 321 Gene3D G3DSA:1.10.240.10 204 298 3.1E-21 T 28-03-2018 CU254_RS32670 0d2be4ea2ce92cc5375890a12fa68299 321 SUPERFAMILY SSF52374 4 315 2.19E-71 T 28-03-2018 CU254_RS32670 0d2be4ea2ce92cc5375890a12fa68299 321 Gene3D G3DSA:3.40.50.620 1 203 1.4E-56 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS32670 0d2be4ea2ce92cc5375890a12fa68299 321 Pfam PF00579 tRNA synthetases class I (W and Y) 4 275 1.7E-55 T 28-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 CU254_RS10770 6a40b784f3894a45ff4b4afc8afc953c 468 SUPERFAMILY SSF55931 130 451 3.6E-68 T 28-03-2018 CU254_RS10770 6a40b784f3894a45ff4b4afc8afc953c 468 Gene3D G3DSA:3.10.20.70 29 126 1.5E-14 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CU254_RS10770 6a40b784f3894a45ff4b4afc8afc953c 468 SMART SM01230 130 378 3.7E-62 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CU254_RS10770 6a40b784f3894a45ff4b4afc8afc953c 468 Gene3D G3DSA:3.30.590.10 127 465 1.0E-77 T 28-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CU254_RS10770 6a40b784f3894a45ff4b4afc8afc953c 468 Pfam PF00120 Glutamine synthetase, catalytic domain 132 450 7.4E-64 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CU254_RS35720 bcaed91f607996e5a5d5c7ff858d78bd 265 Gene3D G3DSA:3.90.850.10 1 265 1.0E-53 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CU254_RS35720 bcaed91f607996e5a5d5c7ff858d78bd 265 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 68 257 2.8E-12 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CU254_RS35720 bcaed91f607996e5a5d5c7ff858d78bd 265 SUPERFAMILY SSF56529 4 259 4.73E-76 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CU254_RS42355 956dec0cac4b6c3b72dd19ebcb576081 303 Gene3D G3DSA:3.90.245.10 1 303 1.3E-72 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CU254_RS42355 956dec0cac4b6c3b72dd19ebcb576081 303 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 7 294 3.3E-61 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CU254_RS42355 956dec0cac4b6c3b72dd19ebcb576081 303 SUPERFAMILY SSF53590 6 301 6.93E-65 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CU254_RS06650 0cfae3ebec211822ebbcd1f0b9ec5fe0 429 SUPERFAMILY SSF51621 7 428 1.3E-158 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CU254_RS06650 0cfae3ebec211822ebbcd1f0b9ec5fe0 429 ProSitePatterns PS00161 Isocitrate lyase signature. 190 195 - T 28-03-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 CU254_RS06650 0cfae3ebec211822ebbcd1f0b9ec5fe0 429 Gene3D G3DSA:3.20.20.60 4 411 1.3E-149 T 28-03-2018 CU254_RS06650 0cfae3ebec211822ebbcd1f0b9ec5fe0 429 PIRSF PIRSF001362 3 429 3.6E-238 T 28-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 CU254_RS06650 0cfae3ebec211822ebbcd1f0b9ec5fe0 429 Pfam PF00463 Isocitrate lyase family 16 252 4.2E-52 T 28-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 CU254_RS06650 0cfae3ebec211822ebbcd1f0b9ec5fe0 429 Pfam PF00463 Isocitrate lyase family 254 428 4.7E-43 T 28-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 CU254_RS06650 0cfae3ebec211822ebbcd1f0b9ec5fe0 429 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 13 252 8.5E-106 T 28-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 CU254_RS32960 c93abdfb07d946a006445f75bd3ac7cc 187 Gene3D G3DSA:3.30.1310.10 12 111 1.2E-14 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CU254_RS32960 c93abdfb07d946a006445f75bd3ac7cc 187 SUPERFAMILY SSF82607 14 103 1.96E-7 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CU254_RS32960 c93abdfb07d946a006445f75bd3ac7cc 187 Pfam PF02575 YbaB/EbfC DNA-binding family 17 102 1.2E-7 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CU254_RS32675 44c549e5da7aa05b452b03d5bf3a0f01 133 Pfam PF00293 NUDIX domain 5 123 1.4E-14 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CU254_RS32675 44c549e5da7aa05b452b03d5bf3a0f01 133 Gene3D G3DSA:3.90.79.10 2 132 1.5E-24 T 28-03-2018 CU254_RS32675 44c549e5da7aa05b452b03d5bf3a0f01 133 SUPERFAMILY SSF55811 5 125 4.06E-27 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CU254_RS32675 44c549e5da7aa05b452b03d5bf3a0f01 133 PRINTS PR00502 NUDIX hydrolase family signature 31 45 8.7E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CU254_RS32675 44c549e5da7aa05b452b03d5bf3a0f01 133 PRINTS PR00502 NUDIX hydrolase family signature 45 60 8.7E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CU254_RS20630 06e214204e974db7e918179826d652e3 135 SUPERFAMILY SSF55298 2 134 1.01E-31 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CU254_RS20630 06e214204e974db7e918179826d652e3 135 Pfam PF01042 Endoribonuclease L-PSP 13 133 1.5E-21 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family CU254_RS20630 06e214204e974db7e918179826d652e3 135 Gene3D G3DSA:3.30.1330.40 2 135 1.3E-30 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CU254_RS21530 1d7a0139eae469287d6754fdaf725195 136 SUPERFAMILY SSF55298 6 134 6.91E-28 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CU254_RS21530 1d7a0139eae469287d6754fdaf725195 136 Pfam PF01042 Endoribonuclease L-PSP 16 131 1.3E-19 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family CU254_RS21530 1d7a0139eae469287d6754fdaf725195 136 Gene3D G3DSA:3.30.1330.40 5 136 8.7E-27 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CU254_RS20220 2ec731946360f7db5f9e790b1f2ef027 157 Pfam PF02577 Bifunctional nuclease 6 127 7.8E-44 T 28-03-2018 IPR003729 Bifunctional nuclease domain GO:0004518 CU254_RS20220 2ec731946360f7db5f9e790b1f2ef027 157 SUPERFAMILY SSF103256 1 136 1.26E-46 T 28-03-2018 IPR003729 Bifunctional nuclease domain GO:0004518 CU254_RS00655 6b01282c40292a574eb4a2c2c043fc05 232 SUPERFAMILY SSF50494 74 188 6.51E-6 T 28-03-2018 IPR009003 Peptidase S1, PA clan CU254_RS00655 6b01282c40292a574eb4a2c2c043fc05 232 Gene3D G3DSA:2.40.10.10 1 113 1.9E-12 T 28-03-2018 CU254_RS22685 e449a83962e33927a9e1fe6caecfdc2c 618 SUPERFAMILY SSF57850 535 615 1.18E-20 T 28-03-2018 CU254_RS22685 e449a83962e33927a9e1fe6caecfdc2c 618 Gene3D G3DSA:3.30.40.10 532 617 2.1E-14 T 28-03-2018 IPR013083 Zinc finger, RING/FYVE/PHD-type CU254_RS22685 e449a83962e33927a9e1fe6caecfdc2c 618 Pfam PF00999 Sodium/hydrogen exchanger family 1 393 1.5E-52 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CU254_RS22685 e449a83962e33927a9e1fe6caecfdc2c 618 TIGRFAM TIGR00831 a_cpa1: Na+/H+ antiporter 1 512 1.3E-90 T 28-03-2018 IPR004705 Cation/H+ exchanger, CPA1 family, bacteria GO:0006812|GO:0015299|GO:0016021 CU254_RS22685 e449a83962e33927a9e1fe6caecfdc2c 618 Pfam PF02148 Zn-finger in ubiquitin-hydrolases and other protein 554 614 5.8E-9 T 28-03-2018 IPR001607 Zinc finger, UBP-type GO:0008270 CU254_RS37640 123cd54e6d7622d5c710ed2d1957c83a 313 Gene3D G3DSA:2.160.20.80 189 295 1.5E-8 T 28-03-2018 CU254_RS37640 123cd54e6d7622d5c710ed2d1957c83a 313 Pfam PF13576 Pentapeptide repeats (9 copies) 249 289 1.4E-6 T 28-03-2018 IPR001646 Pentapeptide repeat CU254_RS37640 123cd54e6d7622d5c710ed2d1957c83a 313 Gene3D G3DSA:1.25.10.20 54 188 2.6E-4 T 28-03-2018 CU254_RS04250 354fc42040706396fac1758968497199 153 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 79 94 4.2E-22 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CU254_RS04250 354fc42040706396fac1758968497199 153 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 47 63 4.2E-22 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CU254_RS04250 354fc42040706396fac1758968497199 153 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 120 135 4.2E-22 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CU254_RS04250 354fc42040706396fac1758968497199 153 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 4 21 4.2E-22 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CU254_RS04250 354fc42040706396fac1758968497199 153 Gene3D G3DSA:3.40.50.2300 1 153 4.5E-48 T 28-03-2018 CU254_RS04250 354fc42040706396fac1758968497199 153 SMART SM00226 2 148 3.0E-49 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CU254_RS04250 354fc42040706396fac1758968497199 153 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 5 146 1.9E-37 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CU254_RS04250 354fc42040706396fac1758968497199 153 SUPERFAMILY SSF52788 2 149 2.75E-43 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CU254_RS23430 7b55fd7d9a680763dac57a04b502c797 307 Gene3D G3DSA:3.10.180.10 3 133 9.2E-10 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS23430 7b55fd7d9a680763dac57a04b502c797 307 Gene3D G3DSA:3.10.180.10 134 300 2.5E-28 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS23430 7b55fd7d9a680763dac57a04b502c797 307 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 143 265 1.6E-19 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CU254_RS23430 7b55fd7d9a680763dac57a04b502c797 307 SUPERFAMILY SSF54593 2 274 8.86E-34 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS14695 da92b79710b443fa911c17bb91f4bd98 197 ProDom PD022816 MAJOR GP23 GP20 CAPSID STRUCTURAL COAT TAIL GP19 DIRECT SEQUENCING 1 173 7.0E-14 T 28-03-2018 CU254_RS08410 c6b00d635705304f6b6aa096a288cdf9 143 SUPERFAMILY SSF55729 12 142 6.73E-32 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS08410 c6b00d635705304f6b6aa096a288cdf9 143 Gene3D G3DSA:3.40.630.30 1 143 1.3E-27 T 28-03-2018 CU254_RS08410 c6b00d635705304f6b6aa096a288cdf9 143 Pfam PF13673 Acetyltransferase (GNAT) domain 50 141 2.4E-16 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS12820 31704882c3c729789d60254fdb28bdef 352 Gene3D G3DSA:3.40.50.300 11 331 1.2E-76 T 28-03-2018 CU254_RS12820 31704882c3c729789d60254fdb28bdef 352 SMART SM00382 45 236 7.9E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS12820 31704882c3c729789d60254fdb28bdef 352 Pfam PF00005 ABC transporter 36 186 3.8E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS12820 31704882c3c729789d60254fdb28bdef 352 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 238 305 2.4E-14 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CU254_RS12820 31704882c3c729789d60254fdb28bdef 352 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS12820 31704882c3c729789d60254fdb28bdef 352 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 236 324 5.6E-17 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CU254_RS12820 31704882c3c729789d60254fdb28bdef 352 SUPERFAMILY SSF52540 14 258 1.15E-70 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS00695 8473fb77167f39a87405a049240f41d0 106 Pfam PF07978 NIPSNAP 6 99 1.1E-17 T 28-03-2018 IPR012577 NIPSNAP CU254_RS00695 8473fb77167f39a87405a049240f41d0 106 SUPERFAMILY SSF54909 2 99 4.29E-18 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS00695 8473fb77167f39a87405a049240f41d0 106 Gene3D G3DSA:3.30.70.100 2 100 1.2E-16 T 28-03-2018 CU254_RS13775 690f3717dc3719ad72dd58c89f609a5b 350 Pfam PF03601 Conserved hypothetical protein 698 24 328 6.7E-72 T 28-03-2018 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 CU254_RS16360 e918143a0d544242b045261f465a33fb 310 Pfam PF01380 SIS domain 54 167 6.4E-8 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CU254_RS16360 e918143a0d544242b045261f465a33fb 310 Gene3D G3DSA:3.40.50.10490 20 171 4.9E-22 T 28-03-2018 CU254_RS16360 e918143a0d544242b045261f465a33fb 310 SUPERFAMILY SSF53697 28 307 8.32E-45 T 28-03-2018 CU254_RS16360 e918143a0d544242b045261f465a33fb 310 Gene3D G3DSA:3.40.50.10490 178 306 1.5E-22 T 28-03-2018 CU254_RS19970 2552337a5e42d2aa97e4d2ee1d34dac8 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 68 3.0E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS19970 2552337a5e42d2aa97e4d2ee1d34dac8 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 4.8E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS19970 2552337a5e42d2aa97e4d2ee1d34dac8 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 4.8E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS19970 2552337a5e42d2aa97e4d2ee1d34dac8 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 4.8E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS19970 2552337a5e42d2aa97e4d2ee1d34dac8 303 Pfam PF03466 LysR substrate binding domain 95 299 1.6E-38 T 28-03-2018 IPR005119 LysR, substrate-binding CU254_RS19970 2552337a5e42d2aa97e4d2ee1d34dac8 303 Gene3D G3DSA:1.10.10.10 1 92 5.8E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS19970 2552337a5e42d2aa97e4d2ee1d34dac8 303 SUPERFAMILY SSF53850 95 302 5.02E-37 T 28-03-2018 CU254_RS19970 2552337a5e42d2aa97e4d2ee1d34dac8 303 Gene3D G3DSA:3.40.190.10 93 184 3.6E-23 T 28-03-2018 CU254_RS19970 2552337a5e42d2aa97e4d2ee1d34dac8 303 Gene3D G3DSA:3.40.190.10 185 274 3.3E-21 T 28-03-2018 CU254_RS19970 2552337a5e42d2aa97e4d2ee1d34dac8 303 SUPERFAMILY SSF46785 5 117 1.16E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS02440 3927f7f3b9124118ca109fd16bd20909 379 SMART SM01240 15 378 1.2E-14 T 28-03-2018 CU254_RS02440 3927f7f3b9124118ca109fd16bd20909 379 SUPERFAMILY SSF51412 9 78 7.48E-58 T 28-03-2018 CU254_RS02440 3927f7f3b9124118ca109fd16bd20909 379 SUPERFAMILY SSF51412 119 378 7.48E-58 T 28-03-2018 CU254_RS02440 3927f7f3b9124118ca109fd16bd20909 379 TIGRFAM TIGR01304 IMP_DH_rel_2: IMP dehydrogenase family protein 5 377 5.5E-166 T 28-03-2018 IPR005992 IMP dehydrogenase-related 2 GO:0016491|GO:0055114 CU254_RS02440 3927f7f3b9124118ca109fd16bd20909 379 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 18 307 3.6E-34 T 28-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 CU254_RS02440 3927f7f3b9124118ca109fd16bd20909 379 Gene3D G3DSA:3.20.20.70 16 378 9.2E-49 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS24850 63351554da8633c68b50d45678cd9282 184 Pfam PF00583 Acetyltransferase (GNAT) family 57 153 2.1E-7 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS24850 63351554da8633c68b50d45678cd9282 184 SUPERFAMILY SSF55729 6 162 1.45E-22 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS24850 63351554da8633c68b50d45678cd9282 184 Gene3D G3DSA:3.40.630.30 5 181 1.2E-24 T 28-03-2018 CU254_RS16825 b2065d498ff867615decd2acded7b606 202 Gene3D G3DSA:3.40.430.10 3 197 1.9E-36 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CU254_RS16825 b2065d498ff867615decd2acded7b606 202 Pfam PF01872 RibD C-terminal domain 5 178 4.1E-20 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CU254_RS16825 b2065d498ff867615decd2acded7b606 202 SUPERFAMILY SSF53597 2 186 2.62E-25 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CU254_RS02320 0ac2a8285585fa982ae0e85acdf15c91 164 Gene3D G3DSA:1.10.287.1060 62 162 1.8E-10 T 28-03-2018 CU254_RS02320 0ac2a8285585fa982ae0e85acdf15c91 164 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 70 161 4.8E-5 T 28-03-2018 IPR022536 ESX-1 secretion-associated protein EspC GO:0009306 CU254_RS38180 8e4ac6c0a08ed0ba0ba24e6c1763f4bc 288 Gene3D G3DSA:3.40.50.2300 138 288 5.5E-36 T 28-03-2018 CU254_RS38180 8e4ac6c0a08ed0ba0ba24e6c1763f4bc 288 Gene3D G3DSA:3.40.50.2300 15 137 2.2E-31 T 28-03-2018 CU254_RS38180 8e4ac6c0a08ed0ba0ba24e6c1763f4bc 288 SUPERFAMILY SSF53822 20 287 2.94E-60 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CU254_RS38180 8e4ac6c0a08ed0ba0ba24e6c1763f4bc 288 Pfam PF13377 Periplasmic binding protein-like domain 125 286 1.2E-33 T 28-03-2018 CU254_RS18410 a6c75fc158a5db466e0654113fb8c859 597 Gene3D G3DSA:2.160.20.10 288 554 7.3E-30 T 28-03-2018 IPR012334 Pectin lyase fold CU254_RS18410 a6c75fc158a5db466e0654113fb8c859 597 SUPERFAMILY SSF51126 309 475 1.82E-7 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor CU254_RS23620 3b9aabe86af8a59cb36712c4295fb7bc 151 Pfam PF01899 Na+/H+ ion antiporter subunit 12 142 4.0E-7 T 28-03-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 CU254_RS22535 5b91ac7de22eecc661ca44d18255b46c 317 Gene3D G3DSA:3.40.1190.20 1 308 3.9E-56 T 28-03-2018 IPR029056 Ribokinase-like CU254_RS22535 5b91ac7de22eecc661ca44d18255b46c 317 SUPERFAMILY SSF53613 1 284 4.21E-64 T 28-03-2018 IPR029056 Ribokinase-like CU254_RS22535 5b91ac7de22eecc661ca44d18255b46c 317 Pfam PF00294 pfkB family carbohydrate kinase 1 279 7.7E-46 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CU254_RS31240 4c31bbbedaa90337bf8ecc7956daf293 188 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 14 184 4.0E-59 T 28-03-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 CU254_RS31240 4c31bbbedaa90337bf8ecc7956daf293 188 SUPERFAMILY SSF89028 7 185 2.94E-57 T 28-03-2018 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 CU254_RS31240 4c31bbbedaa90337bf8ecc7956daf293 188 Gene3D G3DSA:1.20.1200.10 17 188 3.9E-57 T 28-03-2018 CU254_RS31240 4c31bbbedaa90337bf8ecc7956daf293 188 Pfam PF01923 Cobalamin adenosyltransferase 8 175 6.4E-57 T 28-03-2018 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 CU254_RS31240 4c31bbbedaa90337bf8ecc7956daf293 188 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 9 180 1.6E-51 T 28-03-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 CU254_RS22835 4a2ca7e3d2236788b3e6816e78ff6b7c 146 SUPERFAMILY SSF82784 7 144 1.96E-44 T 28-03-2018 IPR003718 OsmC/Ohr family CU254_RS22835 4a2ca7e3d2236788b3e6816e78ff6b7c 146 Pfam PF02566 OsmC-like protein 40 143 9.1E-20 T 28-03-2018 IPR003718 OsmC/Ohr family CU254_RS22835 4a2ca7e3d2236788b3e6816e78ff6b7c 146 Gene3D G3DSA:3.30.300.20 2 136 1.0E-40 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CU254_RS27740 85586f4413d866e1b48a7d210ad355d4 394 Pfam PF01590 GAF domain 102 192 3.0E-6 T 28-03-2018 IPR003018 GAF domain GO:0005515 CU254_RS42600 8b0da1e6d9e9b3c1e96562e372a893cf 380 Gene3D G3DSA:1.10.443.10 164 357 4.5E-21 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CU254_RS42600 8b0da1e6d9e9b3c1e96562e372a893cf 380 SUPERFAMILY SSF56349 167 348 8.83E-23 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CU254_RS42600 8b0da1e6d9e9b3c1e96562e372a893cf 380 Pfam PF00589 Phage integrase family 172 340 4.5E-15 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CU254_RS42600 8b0da1e6d9e9b3c1e96562e372a893cf 380 Gene3D G3DSA:1.10.150.130 53 161 9.8E-6 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CU254_RS16890 3dddad9dc36d15983aa2acc6aa28c6e2 274 SUPERFAMILY SSF117396 1 250 4.45E-59 T 28-03-2018 IPR002763 Protein of unknown function DUF72 CU254_RS16890 3dddad9dc36d15983aa2acc6aa28c6e2 274 Pfam PF01904 Protein of unknown function DUF72 13 249 1.7E-49 T 28-03-2018 IPR002763 Protein of unknown function DUF72 CU254_RS16890 3dddad9dc36d15983aa2acc6aa28c6e2 274 Gene3D G3DSA:3.20.20.410 1 256 2.2E-61 T 28-03-2018 IPR002763 Protein of unknown function DUF72 CU254_RS05505 0524ec0b25331b37c65290d677d6d5ef 301 Gene3D G3DSA:1.10.287.1060 67 161 4.9E-8 T 28-03-2018 CU254_RS05505 0524ec0b25331b37c65290d677d6d5ef 301 SUPERFAMILY SSF140453 69 162 4.32E-5 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CU254_RS37730 3070a2cd1453e0886e37f6cd5aec33a6 286 SUPERFAMILY SSF53335 62 239 9.76E-39 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS37730 3070a2cd1453e0886e37f6cd5aec33a6 286 Pfam PF08241 Methyltransferase domain 96 183 1.7E-22 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CU254_RS37730 3070a2cd1453e0886e37f6cd5aec33a6 286 Gene3D G3DSA:3.40.50.150 59 259 2.0E-32 T 28-03-2018 CU254_RS12930 0ddf6121f2b8e521aeae6c4e752a6bed 477 Pfam PF13520 Amino acid permease 27 426 3.4E-26 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CU254_RS12930 0ddf6121f2b8e521aeae6c4e752a6bed 477 PIRSF PIRSF006060 2 474 2.5E-54 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CU254_RS16055 65e5d210a356e48180ac9dd470dd8ce4 370 SUPERFAMILY SSF48576 58 369 3.45E-38 T 28-03-2018 IPR008949 Isoprenoid synthase domain CU254_RS16055 65e5d210a356e48180ac9dd470dd8ce4 370 Gene3D G3DSA:1.10.600.10 54 365 1.1E-55 T 28-03-2018 IPR008949 Isoprenoid synthase domain CU254_RS08705 6979cea0384db117450af625f03c30db 223 Pfam PF09335 SNARE associated Golgi protein 54 163 3.6E-20 T 28-03-2018 IPR032816 SNARE associated Golgi protein CU254_RS07665 a72e7073f8edf8ecb1a1c829e56a1253 290 Pfam PF01261 Xylose isomerase-like TIM barrel 34 239 2.8E-27 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CU254_RS07665 a72e7073f8edf8ecb1a1c829e56a1253 290 Gene3D G3DSA:3.20.20.150 1 290 1.7E-51 T 28-03-2018 CU254_RS07665 a72e7073f8edf8ecb1a1c829e56a1253 290 SUPERFAMILY SSF51658 30 288 3.54E-48 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CU254_RS12155 54a3aecf91ae6cb104a09c50e8ca6e7c 334 Gene3D G3DSA:2.60.40.420 82 182 2.0E-15 T 28-03-2018 IPR008972 Cupredoxin CU254_RS12155 54a3aecf91ae6cb104a09c50e8ca6e7c 334 PRINTS PR00155 Amicyanin family signature 166 181 3.5E-7 T 28-03-2018 IPR002386 Amicyanin/Pseudoazurin GO:0005507|GO:0009055 CU254_RS12155 54a3aecf91ae6cb104a09c50e8ca6e7c 334 PRINTS PR00155 Amicyanin family signature 110 129 3.5E-7 T 28-03-2018 IPR002386 Amicyanin/Pseudoazurin GO:0005507|GO:0009055 CU254_RS12155 54a3aecf91ae6cb104a09c50e8ca6e7c 334 PRINTS PR00155 Amicyanin family signature 150 165 3.5E-7 T 28-03-2018 IPR002386 Amicyanin/Pseudoazurin GO:0005507|GO:0009055 CU254_RS12155 54a3aecf91ae6cb104a09c50e8ca6e7c 334 SUPERFAMILY SSF49503 88 181 1.54E-26 T 28-03-2018 IPR008972 Cupredoxin CU254_RS12155 54a3aecf91ae6cb104a09c50e8ca6e7c 334 Pfam PF00127 Copper binding proteins, plastocyanin/azurin family 103 182 7.3E-13 T 28-03-2018 IPR000923 Blue (type 1) copper domain GO:0005507|GO:0009055 CU254_RS37620 bcfedd3f80c01343e9ac7f39f22d77a6 217 Gene3D G3DSA:3.90.210.10 52 110 0.0019 T 28-03-2018 CU254_RS37620 bcfedd3f80c01343e9ac7f39f22d77a6 217 Pfam PF07179 SseB protein N-terminal domain 108 207 9.5E-5 T 28-03-2018 IPR009839 SseB protein N-terminal domain CU254_RS17290 4bd1f1ea65f665d60b81f0a3a3f840fe 361 SUPERFAMILY SSF51726 2 346 2.62E-44 T 28-03-2018 CU254_RS17290 4bd1f1ea65f665d60b81f0a3a3f840fe 361 Gene3D G3DSA:3.20.20.210 1 358 1.3E-57 T 28-03-2018 CU254_RS17290 4bd1f1ea65f665d60b81f0a3a3f840fe 361 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 6 323 7.9E-6 T 28-03-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CU254_RS21120 ce4a4c69b5d0f68b3a7b9164b5140b33 413 Gene3D G3DSA:3.30.470.20 109 383 1.7E-20 T 28-03-2018 CU254_RS21120 ce4a4c69b5d0f68b3a7b9164b5140b33 413 SUPERFAMILY SSF56059 113 310 1.18E-21 T 28-03-2018 CU254_RS10460 7147f489498ba0ca022afcf392044850 281 SUPERFAMILY SSF53474 3 279 3.52E-64 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS10460 7147f489498ba0ca022afcf392044850 281 Pfam PF12697 Alpha/beta hydrolase family 29 272 9.6E-21 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS10460 7147f489498ba0ca022afcf392044850 281 PRINTS PR00111 Alpha/beta hydrolase fold signature 100 113 2.2E-20 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS10460 7147f489498ba0ca022afcf392044850 281 PRINTS PR00111 Alpha/beta hydrolase fold signature 55 70 2.2E-20 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS10460 7147f489498ba0ca022afcf392044850 281 PRINTS PR00111 Alpha/beta hydrolase fold signature 114 127 2.2E-20 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS10460 7147f489498ba0ca022afcf392044850 281 PRINTS PR00111 Alpha/beta hydrolase fold signature 224 238 2.2E-20 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS10460 7147f489498ba0ca022afcf392044850 281 Gene3D G3DSA:3.40.50.1820 3 281 7.1E-52 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS13315 a7883d0aa4291544fbedc5fbbc931a72 336 Pfam PF00534 Glycosyl transferases group 1 164 313 2.7E-25 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CU254_RS13315 a7883d0aa4291544fbedc5fbbc931a72 336 Gene3D G3DSA:3.40.50.2000 157 320 3.6E-36 T 28-03-2018 CU254_RS13315 a7883d0aa4291544fbedc5fbbc931a72 336 SUPERFAMILY SSF53756 106 333 3.34E-49 T 28-03-2018 CU254_RS17365 e104844a0d7c2f70c6b264dc57b6c46e 225 SUPERFAMILY SSF50969 17 212 6.98E-19 T 28-03-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like CU254_RS17365 e104844a0d7c2f70c6b264dc57b6c46e 225 Gene3D G3DSA:2.130.10.10 125 222 1.1E-7 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CU254_RS17365 e104844a0d7c2f70c6b264dc57b6c46e 225 Gene3D G3DSA:2.130.10.10 10 124 8.4E-8 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CU254_RS10895 4d0fc0712678a82add42e2defc9b92c9 126 PIRSF PIRSF006910 1 124 4.7E-51 T 28-03-2018 IPR016499 Nucleic acid binding protein, Rv2694c, predicted CU254_RS10895 4d0fc0712678a82add42e2defc9b92c9 126 Gene3D G3DSA:2.40.50.140 37 124 6.2E-9 T 28-03-2018 CU254_RS04900 24373ca1da088c30c92f0cec51ef934b 246 Pfam PF13649 Methyltransferase domain 46 141 2.8E-20 T 28-03-2018 CU254_RS04900 24373ca1da088c30c92f0cec51ef934b 246 SUPERFAMILY SSF53335 3 216 9.04E-40 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS04900 24373ca1da088c30c92f0cec51ef934b 246 Gene3D G3DSA:3.40.50.150 1 224 1.1E-37 T 28-03-2018 CU254_RS38555 6ace2b296fcad421525aa6496b869158 338 SUPERFAMILY SSF81345 11 332 1.31E-73 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CU254_RS38555 6ace2b296fcad421525aa6496b869158 338 Gene3D G3DSA:1.10.3470.10 11 337 2.8E-62 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CU254_RS38555 6ace2b296fcad421525aa6496b869158 338 Pfam PF01032 FecCD transport family 27 332 9.6E-86 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CU254_RS10165 d4f25d4e47a2e3ea64b0eb85f0b6d388 299 Pfam PF13560 Helix-turn-helix domain 13 75 1.0E-14 T 28-03-2018 CU254_RS10165 d4f25d4e47a2e3ea64b0eb85f0b6d388 299 SUPERFAMILY SSF47413 11 71 1.04E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS10165 d4f25d4e47a2e3ea64b0eb85f0b6d388 299 SMART SM00530 17 72 7.1E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS10165 d4f25d4e47a2e3ea64b0eb85f0b6d388 299 Gene3D G3DSA:1.10.260.40 12 94 6.2E-14 T 28-03-2018 CU254_RS18545 cde6bb0c75eda6ae0c4c7f8fc146bfdd 363 SUPERFAMILY SSF56601 3 348 3.47E-73 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CU254_RS18545 cde6bb0c75eda6ae0c4c7f8fc146bfdd 363 Pfam PF00144 Beta-lactamase 52 334 2.8E-30 T 28-03-2018 IPR001466 Beta-lactamase-related CU254_RS18545 cde6bb0c75eda6ae0c4c7f8fc146bfdd 363 Gene3D G3DSA:3.40.710.10 50 362 7.0E-43 T 28-03-2018 CU254_RS35785 c7c4ad3a7303cecc38a34e90c7e75944 326 SUPERFAMILY SSF53335 26 216 6.55E-12 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS35785 c7c4ad3a7303cecc38a34e90c7e75944 326 Pfam PF09243 Mitochondrial small ribosomal subunit Rsm22 51 323 1.0E-89 T 28-03-2018 IPR015324 Ribosomal protein Rsm22-like GO:0006412|GO:0008168 CU254_RS35785 c7c4ad3a7303cecc38a34e90c7e75944 326 Gene3D G3DSA:3.40.50.150 4 291 7.9E-12 T 28-03-2018 CU254_RS05610 dcf7fc2bc179412c897f218f222ac107 194 Gene3D G3DSA:3.40.430.10 2 191 6.2E-32 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CU254_RS05610 dcf7fc2bc179412c897f218f222ac107 194 Pfam PF01872 RibD C-terminal domain 2 186 3.2E-9 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CU254_RS05610 dcf7fc2bc179412c897f218f222ac107 194 SUPERFAMILY SSF53597 2 190 5.11E-27 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CU254_RS41265 3fef1c454676973f485381dc793d1273 246 Gene3D G3DSA:3.40.190.10 41 220 2.2E-4 T 28-03-2018 CU254_RS41265 3fef1c454676973f485381dc793d1273 246 Pfam PF12079 Protein of unknown function (DUF3558) 56 242 9.7E-23 T 28-03-2018 IPR024520 Protein of unknown function DUF3558 CU254_RS34625 273f65f9ed22cbd4810033e6e6ad43d2 201 SUPERFAMILY SSF160467 4 82 4.97E-12 T 28-03-2018 CU254_RS34625 273f65f9ed22cbd4810033e6e6ad43d2 201 SMART SM00796 2 189 4.4E-82 T 28-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D CU254_RS34625 273f65f9ed22cbd4810033e6e6ad43d2 201 SUPERFAMILY SSF50891 78 200 1.02E-40 T 28-03-2018 IPR029000 Cyclophilin-like domain CU254_RS34625 273f65f9ed22cbd4810033e6e6ad43d2 201 Gene3D G3DSA:2.40.100.10 76 201 1.5E-52 T 28-03-2018 IPR029000 Cyclophilin-like domain CU254_RS34625 273f65f9ed22cbd4810033e6e6ad43d2 201 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 4 189 7.1E-66 T 28-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D CU254_RS34625 273f65f9ed22cbd4810033e6e6ad43d2 201 Gene3D G3DSA:3.30.1360.40 1 75 5.7E-15 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CU254_RS33995 6318d78ac9d1c7a29d7249f616586213 237 SUPERFAMILY SSF55729 40 146 1.08E-9 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS33995 6318d78ac9d1c7a29d7249f616586213 237 Pfam PF00583 Acetyltransferase (GNAT) family 46 145 2.2E-5 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS33995 6318d78ac9d1c7a29d7249f616586213 237 Gene3D G3DSA:3.40.630.30 3 203 2.5E-15 T 28-03-2018 CU254_RS26250 38a651f6df5a904fbde48bf5cd11d2a1 626 Gene3D G3DSA:1.10.10.10 6 72 4.0E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS41655 e2a3b3d817367d63b613d3796e3b534f 627 Pfam PF02534 Type IV secretory system Conjugative DNA transfer 170 284 9.5E-8 T 28-03-2018 IPR003688 Type IV secretion system protein TraG/VirD4 GO:0009291|GO:0016020 CU254_RS41655 e2a3b3d817367d63b613d3796e3b534f 627 Gene3D G3DSA:3.40.50.300 118 585 1.9E-17 T 28-03-2018 CU254_RS41655 e2a3b3d817367d63b613d3796e3b534f 627 SUPERFAMILY SSF52540 185 578 5.84E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS41655 e2a3b3d817367d63b613d3796e3b534f 627 Pfam PF12696 TraM recognition site of TraD and TraG 436 553 2.4E-26 T 28-03-2018 IPR032689 TraD/TraG, TraM recognition site CU254_RS18900 ad8f9b2c797fd97a45f694c7db443419 309 Pfam PF06314 Acetoacetate decarboxylase (ADC) 84 222 4.9E-10 T 28-03-2018 IPR010451 Acetoacetate decarboxylase GO:0016829 KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 CU254_RS18900 ad8f9b2c797fd97a45f694c7db443419 309 Gene3D G3DSA:2.40.400.10 41 248 2.8E-25 T 28-03-2018 IPR023375 Acetoacetate decarboxylase beta barrel domain KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 CU254_RS18900 ad8f9b2c797fd97a45f694c7db443419 309 SUPERFAMILY SSF160104 74 222 7.06E-14 T 28-03-2018 IPR023375 Acetoacetate decarboxylase beta barrel domain KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 CU254_RS31500 e2eee307fbe2284544f807467b7f9a53 147 Gene3D G3DSA:1.10.10.10 2 145 1.4E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS31500 e2eee307fbe2284544f807467b7f9a53 147 Pfam PF12802 MarR family 32 91 2.7E-8 T 28-03-2018 CU254_RS31500 e2eee307fbe2284544f807467b7f9a53 147 SUPERFAMILY SSF46785 4 142 2.81E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS31500 e2eee307fbe2284544f807467b7f9a53 147 SMART SM00347 26 129 1.8E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS14285 5f15f06fd5e07847ef959ad532030d75 254 Pfam PF01184 GPR1/FUN34/yaaH family 34 221 1.2E-19 T 28-03-2018 IPR000791 Acetate transporter GPR1/FUN34/SatP family GO:0016021 CU254_RS35125 b2500c07aaf9e3de14233fcfa29f072a 152 ProDom PD034580 PRECURSOR SIGNAL EXPORTED MB0899C RV0875C/MT0898 MLCB57.27C POSSIBLE 21 83 1.0E-4 T 28-03-2018 IPR024495 Protein of unknown function DUF2771 CU254_RS35125 b2500c07aaf9e3de14233fcfa29f072a 152 Pfam PF10969 Protein of unknown function (DUF2771) 15 148 4.7E-19 T 28-03-2018 IPR024495 Protein of unknown function DUF2771 CU254_RS30185 0363827a70a4b9487e85a7bb8eec2931 319 Gene3D G3DSA:3.40.366.10 1 308 7.9E-29 T 28-03-2018 CU254_RS30185 0363827a70a4b9487e85a7bb8eec2931 319 SUPERFAMILY SSF52151 10 130 6.54E-30 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CU254_RS30185 0363827a70a4b9487e85a7bb8eec2931 319 SUPERFAMILY SSF52151 201 300 6.54E-30 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CU254_RS20540 5d2e41c1b33c9d152df2d6f381715f18 271 Gene3D G3DSA:3.60.15.10 2 267 2.6E-20 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS20540 5d2e41c1b33c9d152df2d6f381715f18 271 SUPERFAMILY SSF56281 14 247 3.29E-17 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS20540 5d2e41c1b33c9d152df2d6f381715f18 271 Pfam PF12706 Beta-lactamase superfamily domain 30 224 3.0E-11 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS25850 6d226d8c8a641d7a5fd8ff4ba14de076 287 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 1 246 5.4E-79 T 28-03-2018 IPR014145 DNA ligase D, polymerase domain CU254_RS28595 352e336e5ab435d9c2f27790b672aece 410 SUPERFAMILY SSF53720 7 398 6.94E-57 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CU254_RS28595 352e336e5ab435d9c2f27790b672aece 410 Gene3D G3DSA:3.40.605.10 2 286 9.8E-35 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CU254_RS28595 352e336e5ab435d9c2f27790b672aece 410 Gene3D G3DSA:3.40.309.10 311 375 1.0E-7 T 28-03-2018 CU254_RS28595 352e336e5ab435d9c2f27790b672aece 410 PIRSF PIRSF000151 1 409 1.1E-70 T 28-03-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 CU254_RS28595 352e336e5ab435d9c2f27790b672aece 410 Pfam PF00171 Aldehyde dehydrogenase family 5 287 1.7E-11 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CU254_RS02510 c3795d7c02dd5d5f7cc3fa564fd6569d 424 Gene3D G3DSA:3.30.565.10 288 422 2.3E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS02510 c3795d7c02dd5d5f7cc3fa564fd6569d 424 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 329 417 3.3E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS02510 c3795d7c02dd5d5f7cc3fa564fd6569d 424 SUPERFAMILY SSF55874 327 416 5.24E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS02510 c3795d7c02dd5d5f7cc3fa564fd6569d 424 Pfam PF04024 PspC domain 16 71 5.6E-15 T 28-03-2018 IPR007168 Phage shock protein, PspC, N-terminal CU254_RS00415 9ecc66eb942dd391f984c59771198e22 560 Gene3D G3DSA:3.40.50.1820 15 494 2.3E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS00415 9ecc66eb942dd391f984c59771198e22 560 Pfam PF00561 alpha/beta hydrolase fold 94 276 8.4E-10 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS00415 9ecc66eb942dd391f984c59771198e22 560 SUPERFAMILY SSF53474 94 142 2.67E-10 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS00415 9ecc66eb942dd391f984c59771198e22 560 SUPERFAMILY SSF53474 351 473 2.67E-10 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS00415 9ecc66eb942dd391f984c59771198e22 560 SUPERFAMILY SSF53474 190 244 2.67E-10 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS00415 9ecc66eb942dd391f984c59771198e22 560 Pfam PF08386 TAP-like protein 408 504 1.7E-19 T 28-03-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal CU254_RS33255 e3c627e797380040f13738d38886bcf2 200 Pfam PF09335 SNARE associated Golgi protein 32 159 8.0E-17 T 28-03-2018 IPR032816 SNARE associated Golgi protein CU254_RS15520 a3aca98f0cdfb51db2a75f60f76f713d 152 Pfam PF07883 Cupin domain 48 106 1.0E-12 T 28-03-2018 IPR013096 Cupin 2, conserved barrel CU254_RS15520 a3aca98f0cdfb51db2a75f60f76f713d 152 Gene3D G3DSA:2.60.120.10 6 127 6.7E-20 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS15520 a3aca98f0cdfb51db2a75f60f76f713d 152 SUPERFAMILY SSF51182 9 146 2.05E-23 T 28-03-2018 IPR011051 RmlC-like cupin domain CU254_RS28675 56d507752cc0534fee0c8477b4606d5c 332 Gene3D G3DSA:3.40.50.620 153 294 1.4E-29 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS28675 56d507752cc0534fee0c8477b4606d5c 332 Pfam PF02698 DUF218 domain 159 305 1.0E-28 T 28-03-2018 IPR003848 Domain of unknown function DUF218 CU254_RS01705 adb5a83dd698e1eb2b7bd4158ab409ec 302 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 51 288 1.8E-30 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CU254_RS01705 adb5a83dd698e1eb2b7bd4158ab409ec 302 Gene3D G3DSA:3.40.50.1110 45 300 3.3E-45 T 28-03-2018 CU254_RS01705 adb5a83dd698e1eb2b7bd4158ab409ec 302 SUPERFAMILY SSF52266 47 299 7.0E-68 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CU254_RS34525 0a26093f7e7ec6de93cc39375962b700 132 SUPERFAMILY SSF55620 2 129 1.67E-26 T 28-03-2018 CU254_RS34525 0a26093f7e7ec6de93cc39375962b700 132 Gene3D G3DSA:3.30.479.10 1 132 1.6E-25 T 28-03-2018 CU254_RS34525 0a26093f7e7ec6de93cc39375962b700 132 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 4 129 1.9E-20 T 28-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 CU254_RS16400 e8003b9e52d88e8d3d733f20f8a5efff 488 Pfam PF01979 Amidohydrolase family 55 422 1.3E-24 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CU254_RS16400 e8003b9e52d88e8d3d733f20f8a5efff 488 SUPERFAMILY SSF51556 80 386 1.74E-52 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS16400 e8003b9e52d88e8d3d733f20f8a5efff 488 Gene3D G3DSA:3.20.20.140 65 401 1.3E-38 T 28-03-2018 CU254_RS16400 e8003b9e52d88e8d3d733f20f8a5efff 488 SUPERFAMILY SSF51338 357 464 6.84E-21 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS16400 e8003b9e52d88e8d3d733f20f8a5efff 488 Gene3D G3DSA:2.30.40.10 1 64 4.2E-5 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CU254_RS32995 72f651c88b790440dd0a39b462f0a874 385 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 197 211 - T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CU254_RS32995 72f651c88b790440dd0a39b462f0a874 385 Gene3D G3DSA:3.40.640.10 8 255 9.3E-63 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS32995 72f651c88b790440dd0a39b462f0a874 385 SUPERFAMILY SSF53383 12 384 3.99E-123 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS32995 72f651c88b790440dd0a39b462f0a874 385 PIRSF PIRSF001434 1 385 5.5E-148 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CU254_RS32995 72f651c88b790440dd0a39b462f0a874 385 Gene3D G3DSA:3.90.1150.10 257 385 5.2E-49 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS32995 72f651c88b790440dd0a39b462f0a874 385 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 11 384 1.3E-148 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CU254_RS29140 ec695c10065150a7c7c2bffb7f074adf 114 Gene3D G3DSA:1.10.10.60 33 83 0.0013 T 28-03-2018 CU254_RS29140 ec695c10065150a7c7c2bffb7f074adf 114 Gene3D G3DSA:1.10.10.60 7 32 5.4E-4 T 28-03-2018 CU254_RS23390 5baf10b0790f696b3346a8af739783c5 395 Gene3D G3DSA:3.40.50.300 29 182 9.7E-20 T 28-03-2018 CU254_RS23390 5baf10b0790f696b3346a8af739783c5 395 Pfam PF07728 AAA domain (dynein-related subfamily) 44 177 2.1E-9 T 28-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 CU254_RS23390 5baf10b0790f696b3346a8af739783c5 395 SMART SM00382 41 187 0.0012 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS23390 5baf10b0790f696b3346a8af739783c5 395 SUPERFAMILY SSF52540 29 185 3.59E-21 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS21915 f0e0c3e6c5d65fcb9e51407fe05b262a 277 Gene3D G3DSA:3.90.850.10 28 277 3.6E-38 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CU254_RS21915 f0e0c3e6c5d65fcb9e51407fe05b262a 277 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 100 272 4.8E-21 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CU254_RS21915 f0e0c3e6c5d65fcb9e51407fe05b262a 277 SUPERFAMILY SSF56529 59 272 6.02E-31 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CU254_RS05935 0eb106baedd7f02fcf92b8daec9a3f7b 475 Gene3D G3DSA:3.30.565.10 321 471 9.9E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS05935 0eb106baedd7f02fcf92b8daec9a3f7b 475 Pfam PF00027 Cyclic nucleotide-binding domain 35 120 9.9E-12 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CU254_RS05935 0eb106baedd7f02fcf92b8daec9a3f7b 475 SMART SM00387 363 471 1.8E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS05935 0eb106baedd7f02fcf92b8daec9a3f7b 475 SUPERFAMILY SSF51206 8 133 5.63E-20 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like CU254_RS05935 0eb106baedd7f02fcf92b8daec9a3f7b 475 Gene3D G3DSA:2.60.120.10 6 139 5.6E-16 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS05935 0eb106baedd7f02fcf92b8daec9a3f7b 475 SMART SM00100 16 138 3.2E-11 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CU254_RS05935 0eb106baedd7f02fcf92b8daec9a3f7b 475 PRINTS PR00344 Bacterial sensor protein C-terminal signature 431 449 7.3E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS05935 0eb106baedd7f02fcf92b8daec9a3f7b 475 PRINTS PR00344 Bacterial sensor protein C-terminal signature 400 414 7.3E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS05935 0eb106baedd7f02fcf92b8daec9a3f7b 475 PRINTS PR00344 Bacterial sensor protein C-terminal signature 455 468 7.3E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS05935 0eb106baedd7f02fcf92b8daec9a3f7b 475 PRINTS PR00344 Bacterial sensor protein C-terminal signature 418 428 7.3E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CU254_RS05935 0eb106baedd7f02fcf92b8daec9a3f7b 475 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 367 470 4.7E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS05935 0eb106baedd7f02fcf92b8daec9a3f7b 475 SUPERFAMILY SSF55874 311 469 5.63E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS05935 0eb106baedd7f02fcf92b8daec9a3f7b 475 ProSitePatterns PS00888 Cyclic nucleotide-binding domain signature 1. 43 59 - T 28-03-2018 IPR018488 Cyclic nucleotide-binding, conserved site CU254_RS07685 1d3edf52bb6cf58bbee646811a5aefe0 219 SUPERFAMILY SSF51735 5 219 3.33E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS07685 1d3edf52bb6cf58bbee646811a5aefe0 219 Pfam PF00106 short chain dehydrogenase 6 177 3.5E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS07685 1d3edf52bb6cf58bbee646811a5aefe0 219 Gene3D G3DSA:3.40.50.720 1 219 1.9E-34 T 28-03-2018 CU254_RS07685 1d3edf52bb6cf58bbee646811a5aefe0 219 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 112 128 1.2E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS07685 1d3edf52bb6cf58bbee646811a5aefe0 219 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 66 77 1.2E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS07685 1d3edf52bb6cf58bbee646811a5aefe0 219 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 1.2E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS07685 1d3edf52bb6cf58bbee646811a5aefe0 219 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 141 160 1.2E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS28250 e02e0ff500432c9f259189792283ca48 119 SUPERFAMILY SSF54909 3 113 1.79E-29 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS28250 e02e0ff500432c9f259189792283ca48 119 Pfam PF03795 YCII-related domain 3 101 1.3E-19 T 28-03-2018 IPR005545 YCII-related CU254_RS28250 e02e0ff500432c9f259189792283ca48 119 Gene3D G3DSA:3.30.70.1060 1 117 1.1E-37 T 28-03-2018 CU254_RS10525 cafca96dd30c784412dc6ef817c9c469 390 Pfam PF06772 Bacterial low temperature requirement A protein (LtrA) 9 366 4.3E-48 T 28-03-2018 IPR010640 Low temperature requirement A CU254_RS03535 fdbd3a9792035a87dd9a8797ba38ff4c 199 Gene3D G3DSA:3.30.530.20 32 195 2.3E-22 T 28-03-2018 IPR023393 START-like domain CU254_RS03535 fdbd3a9792035a87dd9a8797ba38ff4c 199 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 49 194 2.5E-10 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase CU254_RS03535 fdbd3a9792035a87dd9a8797ba38ff4c 199 SUPERFAMILY SSF55961 45 196 3.34E-23 T 28-03-2018 CU254_RS33690 eb0cfe5774b00d6c77253413e96a5c91 168 Pfam PF09335 SNARE associated Golgi protein 36 161 3.8E-18 T 28-03-2018 IPR032816 SNARE associated Golgi protein CU254_RS29450 085617240105cb08e2b47846c5e3da4f 524 Gene3D G3DSA:1.10.10.60 396 496 4.2E-4 T 28-03-2018 CU254_RS29450 085617240105cb08e2b47846c5e3da4f 524 Pfam PF13556 PucR C-terminal helix-turn-helix domain 462 518 1.1E-20 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CU254_RS28915 dc3199b683556dcbb5158e0efe2d5f3b 289 Pfam PF13230 Glutamine amidotransferases class-II 1 253 2.5E-22 T 28-03-2018 IPR026869 Putative glutamine amidotransferase type 2 CU254_RS28915 dc3199b683556dcbb5158e0efe2d5f3b 289 SUPERFAMILY SSF56235 2 256 1.16E-30 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CU254_RS28915 dc3199b683556dcbb5158e0efe2d5f3b 289 Gene3D G3DSA:3.60.20.10 1 264 3.3E-38 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CU254_RS11905 58ef5770af2a78337da1bfa130fd897c 69 Gene3D G3DSA:1.10.10.60 6 54 0.001 T 28-03-2018 CU254_RS06795 73f4e7526f5e05e15095e11ed2b2042c 131 SMART SM00740 58 130 2.0E-6 T 28-03-2018 IPR005543 PASTA domain CU254_RS34390 cf9e37e096523b6440296222dbd60186 339 SUPERFAMILY SSF51445 33 333 4.57E-11 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS34390 cf9e37e096523b6440296222dbd60186 339 Gene3D G3DSA:3.20.20.80 19 339 8.5E-21 T 28-03-2018 CU254_RS07185 ec6259137897648af2a9b9e53dc702c5 409 Pfam PF05139 Erythromycin esterase 51 394 1.6E-51 T 28-03-2018 IPR007815 Erythromycin esterase GO:0046677 CU254_RS07185 ec6259137897648af2a9b9e53dc702c5 409 SUPERFAMILY SSF159501 2 396 7.59E-72 T 28-03-2018 CU254_RS07185 ec6259137897648af2a9b9e53dc702c5 409 Gene3D G3DSA:3.40.1660.10 209 400 3.6E-18 T 28-03-2018 CU254_RS07185 ec6259137897648af2a9b9e53dc702c5 409 Gene3D G3DSA:3.40.1660.10 1 208 3.2E-19 T 28-03-2018 CU254_RS17390 6244ea29d3ab1f4caa44eee06b604923 299 PIRSF PIRSF037505 2 297 3.6E-8 T 28-03-2018 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT GO:0005737|GO:0008270|GO:0009086|GO:0047150 Reactome: R-HSA-1614635 CU254_RS17390 6244ea29d3ab1f4caa44eee06b604923 299 SUPERFAMILY SSF82282 3 294 4.84E-65 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CU254_RS17390 6244ea29d3ab1f4caa44eee06b604923 299 Gene3D G3DSA:3.20.20.330 2 297 6.9E-69 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CU254_RS17390 6244ea29d3ab1f4caa44eee06b604923 299 Pfam PF02574 Homocysteine S-methyltransferase 6 291 3.3E-56 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CU254_RS33680 fb2dd4fd0367f3fe9198c85859338950 316 Pfam PF00296 Luciferase-like monooxygenase 2 243 1.2E-48 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS33680 fb2dd4fd0367f3fe9198c85859338950 316 Gene3D G3DSA:3.20.20.30 1 303 1.3E-61 T 28-03-2018 CU254_RS33680 fb2dd4fd0367f3fe9198c85859338950 316 SUPERFAMILY SSF51679 2 302 2.22E-54 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS08180 013fdf171843b9ba969f396c94b9cc02 293 Gene3D G3DSA:3.40.50.1820 14 292 1.0E-41 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS08180 013fdf171843b9ba969f396c94b9cc02 293 PRINTS PR00412 Epoxide hydrolase signature 40 58 5.8E-5 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS08180 013fdf171843b9ba969f396c94b9cc02 293 PRINTS PR00412 Epoxide hydrolase signature 103 116 5.8E-5 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS08180 013fdf171843b9ba969f396c94b9cc02 293 PRINTS PR00412 Epoxide hydrolase signature 117 130 5.8E-5 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS08180 013fdf171843b9ba969f396c94b9cc02 293 Pfam PF00561 alpha/beta hydrolase fold 34 273 8.0E-20 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS08180 013fdf171843b9ba969f396c94b9cc02 293 SUPERFAMILY SSF53474 22 290 1.07E-61 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS08180 013fdf171843b9ba969f396c94b9cc02 293 ProSitePatterns PS00560 Serine carboxypeptidases, histidine active site. 261 278 - T 28-03-2018 IPR033124 Serine carboxypeptidases, histidine active site Reactome: R-HSA-1660662|Reactome: R-HSA-2132295|Reactome: R-HSA-4085001|Reactome: R-HSA-6798695 CU254_RS37010 c073336def3924ef37d0a8b63029cb9a 140 SUPERFAMILY SSF54427 3 123 6.17E-27 T 28-03-2018 IPR032710 NTF2-like domain CU254_RS37010 c073336def3924ef37d0a8b63029cb9a 140 Pfam PF13474 SnoaL-like domain 6 126 4.8E-20 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CU254_RS37010 c073336def3924ef37d0a8b63029cb9a 140 Gene3D G3DSA:3.10.450.50 1 133 4.7E-25 T 28-03-2018 CU254_RS28655 02d32989cb00f0b55730002abade73de 128 Pfam PF11528 Protein of unknown function (DUF3224) 7 123 8.2E-32 T 28-03-2018 IPR021607 Protein of unknown function DUF3224 CU254_RS28655 02d32989cb00f0b55730002abade73de 128 Gene3D G3DSA:2.40.350.10 1 128 8.3E-36 T 28-03-2018 IPR023159 SO1590-like domain CU254_RS28655 02d32989cb00f0b55730002abade73de 128 SUPERFAMILY SSF159238 1 126 5.36E-33 T 28-03-2018 IPR023159 SO1590-like domain CU254_RS40665 50eda1c06952501176a35a3a0f30ba11 494 TIGRFAM TIGR03605 antibiot_sagB: SagB-type dehydrogenase domain 283 459 1.3E-49 T 28-03-2018 IPR020051 SagB-type dehydrogenase domain CU254_RS40665 50eda1c06952501176a35a3a0f30ba11 494 SUPERFAMILY SSF55469 265 460 3.75E-12 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CU254_RS40665 50eda1c06952501176a35a3a0f30ba11 494 Gene3D G3DSA:3.40.109.10 205 459 1.3E-28 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CU254_RS40665 50eda1c06952501176a35a3a0f30ba11 494 Pfam PF00881 Nitroreductase family 268 447 1.0E-15 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CU254_RS37830 a17b99f6bdda0104a814c7a1884ec0ff 137 Gene3D G3DSA:3.30.1330.40 6 137 3.7E-29 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CU254_RS37830 a17b99f6bdda0104a814c7a1884ec0ff 137 SUPERFAMILY SSF55298 20 135 1.88E-31 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CU254_RS37830 a17b99f6bdda0104a814c7a1884ec0ff 137 Pfam PF01042 Endoribonuclease L-PSP 24 134 2.9E-22 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family CU254_RS04335 88c0fc361ff731e339d5207cb5110494 319 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 7 131 1.4E-7 T 28-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CU254_RS04335 88c0fc361ff731e339d5207cb5110494 319 SUPERFAMILY SSF52540 2 64 1.22E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS04335 88c0fc361ff731e339d5207cb5110494 319 SUPERFAMILY SSF52540 99 271 1.22E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS04335 88c0fc361ff731e339d5207cb5110494 319 Gene3D G3DSA:3.40.50.300 2 289 4.9E-35 T 28-03-2018 CU254_RS39035 c3a81b794ab116777a23c0ba455aa717 223 Pfam PF08044 Domain of unknown function (DUF1707) 26 78 3.7E-22 T 28-03-2018 IPR012551 Protein of unknown function DUF1707 CU254_RS04585 c6ab10e60ddd06b9e8cba9eaae0797de 411 Pfam PF14065 Protein of unknown function (DUF4255) 9 186 4.0E-35 T 28-03-2018 IPR025351 Protein of unknown function DUF4255 CU254_RS05575 ee459795a8a91d6d54ebb4da1da861b7 204 Gene3D G3DSA:3.90.226.10 15 187 3.2E-30 T 28-03-2018 CU254_RS05575 ee459795a8a91d6d54ebb4da1da861b7 204 Pfam PF00574 Clp protease 14 185 1.6E-51 T 28-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA CU254_RS05575 ee459795a8a91d6d54ebb4da1da861b7 204 PRINTS PR00127 Clp protease catalytic subunit P signature 162 181 1.7E-29 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CU254_RS05575 ee459795a8a91d6d54ebb4da1da861b7 204 PRINTS PR00127 Clp protease catalytic subunit P signature 53 73 1.7E-29 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CU254_RS05575 ee459795a8a91d6d54ebb4da1da861b7 204 PRINTS PR00127 Clp protease catalytic subunit P signature 13 28 1.7E-29 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CU254_RS05575 ee459795a8a91d6d54ebb4da1da861b7 204 PRINTS PR00127 Clp protease catalytic subunit P signature 84 101 1.7E-29 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CU254_RS05575 ee459795a8a91d6d54ebb4da1da861b7 204 PRINTS PR00127 Clp protease catalytic subunit P signature 105 124 1.7E-29 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CU254_RS05575 ee459795a8a91d6d54ebb4da1da861b7 204 SUPERFAMILY SSF52096 9 188 8.48E-50 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS35690 fe99f941dafbf7476319c7ecbd13acd1 473 SUPERFAMILY SSF47240 107 335 5.14E-45 T 28-03-2018 IPR009078 Ferritin-like superfamily CU254_RS35690 fe99f941dafbf7476319c7ecbd13acd1 473 TIGRFAM TIGR03225 benzo_boxB: benzoyl-CoA oxygenase, B subunit 5 471 1.5E-227 T 28-03-2018 IPR017635 Benzoyl-CoA oxygenase, B subunit KEGG: 00361+1.14.13.20|MetaCyc: PWY-1361|MetaCyc: PWY-6085|MetaCyc: PWY-6086 CU254_RS35690 fe99f941dafbf7476319c7ecbd13acd1 473 Gene3D G3DSA:1.20.1260.10 97 452 2.6E-94 T 28-03-2018 IPR012347 Ferritin-related CU254_RS21925 ba5bb71115b5d5c613afa2077b1f5b72 91 Pfam PF02325 YGGT family 10 87 3.1E-14 T 28-03-2018 IPR003425 CCB3/YggT GO:0016020 CU254_RS07955 60e263f9c07f90bdf488ddc8ba922ae8 240 Pfam PF02517 CAAX protease self-immunity 143 230 1.1E-13 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CU254_RS01850 1245e1ae94dc2b53d7e1f676d443667a 208 Gene3D G3DSA:2.20.28.20 186 208 0.023 T 28-03-2018 CU254_RS01850 1245e1ae94dc2b53d7e1f676d443667a 208 Gene3D G3DSA:2.20.28.20 158 185 3.3E-6 T 28-03-2018 CU254_RS30230 a645a571d087543fa69d48e86a4c53a8 240 SUPERFAMILY SSF54593 14 182 1.77E-23 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS30230 a645a571d087543fa69d48e86a4c53a8 240 Gene3D G3DSA:3.10.180.10 3 29 0.0017 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS30230 a645a571d087543fa69d48e86a4c53a8 240 Gene3D G3DSA:3.10.180.10 30 129 2.4E-16 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS30230 a645a571d087543fa69d48e86a4c53a8 240 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 135 236 9.8E-5 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CU254_RS30230 a645a571d087543fa69d48e86a4c53a8 240 Gene3D G3DSA:3.10.180.10 130 240 3.0E-16 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS31705 bbce20463de496d07fa4f06dc8ef5b87 199 SMART SM00347 29 129 2.6E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS31705 bbce20463de496d07fa4f06dc8ef5b87 199 SUPERFAMILY SSF46785 8 141 3.43E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS31705 bbce20463de496d07fa4f06dc8ef5b87 199 Gene3D G3DSA:1.10.10.10 3 175 9.4E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS31705 bbce20463de496d07fa4f06dc8ef5b87 199 Pfam PF12802 MarR family 35 95 2.3E-9 T 28-03-2018 CU254_RS25110 35c50612cd882be07ad72769463badf7 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 1.4E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS25110 35c50612cd882be07ad72769463badf7 202 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 1.4E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS25110 35c50612cd882be07ad72769463badf7 202 SUPERFAMILY SSF46689 5 84 1.6E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS25110 35c50612cd882be07ad72769463badf7 202 Gene3D G3DSA:1.10.10.60 5 68 2.1E-19 T 28-03-2018 CU254_RS25110 35c50612cd882be07ad72769463badf7 202 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 59 2.6E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS25110 35c50612cd882be07ad72769463badf7 202 Gene3D G3DSA:1.10.357.10 69 200 1.9E-23 T 28-03-2018 CU254_RS13665 4f703aee3a643bc06bb137cdc7c661b7 356 Gene3D G3DSA:1.10.357.10 1 224 2.9E-25 T 28-03-2018 CU254_RS13665 4f703aee3a643bc06bb137cdc7c661b7 356 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 63 5.3E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS13665 4f703aee3a643bc06bb137cdc7c661b7 356 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 1.0E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS13665 4f703aee3a643bc06bb137cdc7c661b7 356 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 1.0E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS13665 4f703aee3a643bc06bb137cdc7c661b7 356 SUPERFAMILY SSF46689 3 77 2.26E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS11920 277d33ab5587380ecda51d835a0e20a2 242 Pfam PF13580 SIS domain 10 141 1.8E-34 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CU254_RS11920 277d33ab5587380ecda51d835a0e20a2 242 SUPERFAMILY SSF53697 8 200 1.01E-17 T 28-03-2018 CU254_RS11920 277d33ab5587380ecda51d835a0e20a2 242 Gene3D G3DSA:3.40.50.10490 2 237 1.3E-28 T 28-03-2018 CU254_RS25800 1f872180eea6aa47babc1e61b1c1c292 286 Pfam PF06386 Gas vesicle synthesis protein GvpL/GvpF 41 283 2.6E-57 T 28-03-2018 IPR009430 Gas vesicle protein GvpL/GvpF GO:0031411|GO:0031412 CU254_RS37905 aad90a75dfe71b918c493534900d92eb 378 SUPERFAMILY SSF51695 46 370 7.33E-73 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CU254_RS37905 aad90a75dfe71b918c493534900d92eb 378 Gene3D G3DSA:3.20.20.190 45 373 5.1E-66 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CU254_RS37905 aad90a75dfe71b918c493534900d92eb 378 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 52 367 1.1E-46 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CU254_RS08985 f19ed8984488601c024d15f8351b085f 241 SUPERFAMILY SSF88697 16 212 1.39E-38 T 28-03-2018 IPR015947 PUA-like domain CU254_RS08985 f19ed8984488601c024d15f8351b085f 241 Gene3D G3DSA:1.10.4060.10 130 221 8.2E-13 T 28-03-2018 CU254_RS08985 f19ed8984488601c024d15f8351b085f 241 Gene3D G3DSA:2.30.130.40 2 128 6.9E-29 T 28-03-2018 CU254_RS08985 f19ed8984488601c024d15f8351b085f 241 SMART SM00464 16 213 4.1E-17 T 28-03-2018 IPR003111 Lon, substrate-binding domain CU254_RS08985 f19ed8984488601c024d15f8351b085f 241 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 16 213 1.1E-25 T 28-03-2018 IPR003111 Lon, substrate-binding domain CU254_RS24740 0a5ed54e5cff61dcae77ca7c04097c29 215 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 33 203 2.5E-39 T 28-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 CU254_RS24740 0a5ed54e5cff61dcae77ca7c04097c29 215 PIRSF PIRSF000847 30 212 1.2E-46 T 28-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 CU254_RS24740 0a5ed54e5cff61dcae77ca7c04097c29 215 Pfam PF01066 CDP-alcohol phosphatidyltransferase 33 103 1.5E-14 T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CU254_RS24740 0a5ed54e5cff61dcae77ca7c04097c29 215 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 81 103 - T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CU254_RS38085 8694b82538d7fe3e672fe602ec3fe883 193 Gene3D G3DSA:3.40.50.150 24 189 3.0E-24 T 28-03-2018 CU254_RS38085 8694b82538d7fe3e672fe602ec3fe883 193 SUPERFAMILY SSF53335 6 185 2.15E-36 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS38085 8694b82538d7fe3e672fe602ec3fe883 193 Pfam PF13649 Methyltransferase domain 43 128 6.8E-14 T 28-03-2018 CU254_RS40470 55f36131ada8256ad343953ce68177d0 163 SUPERFAMILY SSF46785 8 154 2.12E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS40470 55f36131ada8256ad343953ce68177d0 163 Pfam PF12802 MarR family 40 101 2.3E-12 T 28-03-2018 CU254_RS40470 55f36131ada8256ad343953ce68177d0 163 PRINTS PR00598 Bacterial regulatory protein MarR family signature 97 113 2.8E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS40470 55f36131ada8256ad343953ce68177d0 163 PRINTS PR00598 Bacterial regulatory protein MarR family signature 128 148 2.8E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS40470 55f36131ada8256ad343953ce68177d0 163 PRINTS PR00598 Bacterial regulatory protein MarR family signature 61 77 2.8E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS40470 55f36131ada8256ad343953ce68177d0 163 PRINTS PR00598 Bacterial regulatory protein MarR family signature 78 93 2.8E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS40470 55f36131ada8256ad343953ce68177d0 163 Gene3D G3DSA:1.10.10.10 20 162 5.2E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS40470 55f36131ada8256ad343953ce68177d0 163 SMART SM00347 35 138 1.1E-18 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS38660 c23837cab30a1b3d68b80093be849e29 396 Gene3D G3DSA:3.40.50.300 19 234 9.5E-12 T 28-03-2018 CU254_RS38660 c23837cab30a1b3d68b80093be849e29 396 SUPERFAMILY SSF52540 6 292 7.03E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS38660 c23837cab30a1b3d68b80093be849e29 396 Gene3D G3DSA:1.10.10.10 315 393 0.0012 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS38660 c23837cab30a1b3d68b80093be849e29 396 Pfam PF13191 AAA ATPase domain 19 209 3.8E-23 T 28-03-2018 CU254_RS36350 5a7ac6ec821fa842a63f20b70daf0dcb 122 Gene3D G3DSA:1.10.287.850 17 114 6.4E-5 T 28-03-2018 CU254_RS04215 f50beb906c2e88198f15f9795d666aa5 113 Pfam PF12840 Helix-turn-helix domain 5 65 2.3E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS04215 f50beb906c2e88198f15f9795d666aa5 113 Gene3D G3DSA:1.10.10.10 2 94 2.8E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS04215 f50beb906c2e88198f15f9795d666aa5 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 56 71 8.7E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS04215 f50beb906c2e88198f15f9795d666aa5 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 41 56 8.7E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS04215 f50beb906c2e88198f15f9795d666aa5 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 8 23 8.7E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS04215 f50beb906c2e88198f15f9795d666aa5 113 SUPERFAMILY SSF46785 5 101 1.32E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS04215 f50beb906c2e88198f15f9795d666aa5 113 SMART SM00418 6 85 3.0E-16 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS38610 897ffc2781dbdf95551fd90cb0cb6d1b 142 SUPERFAMILY SSF52980 8 133 2.79E-36 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CU254_RS38610 897ffc2781dbdf95551fd90cb0cb6d1b 142 Gene3D G3DSA:3.40.960.10 24 141 8.3E-26 T 28-03-2018 CU254_RS38610 897ffc2781dbdf95551fd90cb0cb6d1b 142 TIGRFAM TIGR00632 vsr: DNA mismatch endonuclease Vsr 14 123 5.3E-34 T 28-03-2018 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 CU254_RS38610 897ffc2781dbdf95551fd90cb0cb6d1b 142 Pfam PF03852 DNA mismatch endonuclease Vsr 10 76 1.5E-18 T 28-03-2018 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 CU254_RS16240 77c82502185393f83abf6721e163ec14 543 Pfam PF00135 Carboxylesterase family 46 516 1.9E-91 T 28-03-2018 IPR002018 Carboxylesterase, type B CU254_RS16240 77c82502185393f83abf6721e163ec14 543 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 208 223 - T 28-03-2018 IPR019826 Carboxylesterase type B, active site CU254_RS16240 77c82502185393f83abf6721e163ec14 543 Gene3D G3DSA:3.40.50.1820 42 543 2.0E-110 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS16240 77c82502185393f83abf6721e163ec14 543 SUPERFAMILY SSF53474 45 530 3.59E-99 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS27880 8c05e01513a45cb538f411e23a2f9216 93 Pfam PF02583 Metal-sensitive transcriptional repressor 7 88 1.4E-30 T 28-03-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 CU254_RS29830 5de81c32e1c79322f5b68189eedf5162 377 Gene3D G3DSA:3.90.820.10 13 67 4.1E-10 T 28-03-2018 CU254_RS29950 a815846a73fdec456ec642833bf17360 171 Gene3D G3DSA:2.70.50.50 31 171 6.4E-32 T 28-03-2018 CU254_RS29950 a815846a73fdec456ec642833bf17360 171 SUPERFAMILY SSF81296 31 170 7.28E-34 T 28-03-2018 IPR014756 Immunoglobulin E-set CU254_RS29950 a815846a73fdec456ec642833bf17360 171 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 31 168 3.7E-17 T 28-03-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal CU254_RS32820 f10318fec4c19d600310c5d7ae8a6416 295 Pfam PF00892 EamA-like transporter family 141 274 5.5E-15 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CU254_RS32820 f10318fec4c19d600310c5d7ae8a6416 295 Pfam PF00892 EamA-like transporter family 3 133 3.6E-13 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CU254_RS32820 f10318fec4c19d600310c5d7ae8a6416 295 SUPERFAMILY SSF103481 196 280 7.32E-8 T 28-03-2018 CU254_RS32820 f10318fec4c19d600310c5d7ae8a6416 295 SUPERFAMILY SSF103481 33 136 7.85E-12 T 28-03-2018 CU254_RS31595 302fe87bf7710a6b2daefb859c7083e7 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 61 4.9E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS31595 302fe87bf7710a6b2daefb859c7083e7 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 2.6E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS31595 302fe87bf7710a6b2daefb859c7083e7 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 2.6E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS31595 302fe87bf7710a6b2daefb859c7083e7 191 ProSitePatterns PS01081 TetR-type HTH domain signature. 29 59 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CU254_RS31595 302fe87bf7710a6b2daefb859c7083e7 191 SUPERFAMILY SSF48498 84 189 6.37E-26 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS31595 302fe87bf7710a6b2daefb859c7083e7 191 SUPERFAMILY SSF46689 3 67 5.64E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS31595 302fe87bf7710a6b2daefb859c7083e7 191 Gene3D G3DSA:1.10.357.10 65 191 1.1E-28 T 28-03-2018 CU254_RS31595 302fe87bf7710a6b2daefb859c7083e7 191 Gene3D G3DSA:1.10.10.60 1 61 7.1E-21 T 28-03-2018 CU254_RS15385 434d73fa0e88f8c8c7b1fa6dedc4a1da 193 Gene3D G3DSA:3.30.530.20 40 193 1.8E-17 T 28-03-2018 IPR023393 START-like domain CU254_RS15385 434d73fa0e88f8c8c7b1fa6dedc4a1da 193 SUPERFAMILY SSF55961 52 190 3.85E-19 T 28-03-2018 CU254_RS15385 434d73fa0e88f8c8c7b1fa6dedc4a1da 193 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 54 164 1.6E-6 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase CU254_RS27835 42310685048b5b24ce3b2fccb4d3981e 244 Pfam PF00975 Thioesterase domain 18 233 5.9E-51 T 28-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CU254_RS27835 42310685048b5b24ce3b2fccb4d3981e 244 Gene3D G3DSA:3.40.50.1820 1 240 5.6E-39 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS27835 42310685048b5b24ce3b2fccb4d3981e 244 SMART SM00824 Thioesterase 20 240 6.7E-6 T 28-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 CU254_RS27835 42310685048b5b24ce3b2fccb4d3981e 244 SUPERFAMILY SSF53474 3 237 3.37E-52 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS30690 aa7a6900efe98d4db8a688974eb166b8 391 SUPERFAMILY SSF53955 98 265 3.09E-35 T 28-03-2018 IPR023346 Lysozyme-like domain CU254_RS30690 aa7a6900efe98d4db8a688974eb166b8 391 Gene3D G3DSA:1.10.530.10 103 338 2.2E-28 T 28-03-2018 CU254_RS30690 aa7a6900efe98d4db8a688974eb166b8 391 Pfam PF13406 Transglycosylase SLT domain 185 231 5.8E-8 T 28-03-2018 IPR031304 Transglycosylase SLT domain 2 CU254_RS11290 c3ad425197525d084de1528ad9d06662 283 Gene3D G3DSA:3.40.50.1110 16 224 3.9E-28 T 28-03-2018 CU254_RS11290 c3ad425197525d084de1528ad9d06662 283 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 36 212 3.1E-19 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CU254_RS11290 c3ad425197525d084de1528ad9d06662 283 SUPERFAMILY SSF52266 32 219 2.14E-27 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CU254_RS29005 f817533f8e8b3177dec11839f4631a11 118 Gene3D G3DSA:1.10.10.10 9 118 1.4E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS29005 f817533f8e8b3177dec11839f4631a11 118 SUPERFAMILY SSF46785 13 115 2.87E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS29005 f817533f8e8b3177dec11839f4631a11 118 Pfam PF01638 HxlR-like helix-turn-helix 24 114 1.9E-28 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type CU254_RS41320 856620382d172c21e43e086839b65075 116 Pfam PF05331 Protein of unknown function (DUF742) 9 116 3.3E-22 T 28-03-2018 IPR007995 Protein of unknown function DUF742 CU254_RS22250 c4224f552e9df2061da151ea4caf0629 186 Pfam PF01553 Acyltransferase 1 120 9.8E-21 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CU254_RS22250 c4224f552e9df2061da151ea4caf0629 186 SUPERFAMILY SSF69593 3 175 2.88E-33 T 28-03-2018 CU254_RS22250 c4224f552e9df2061da151ea4caf0629 186 Gene3D G3DSA:3.40.1130.10 1 177 6.1E-37 T 28-03-2018 CU254_RS22250 c4224f552e9df2061da151ea4caf0629 186 SMART SM00563 13 123 1.2E-27 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CU254_RS40610 e84d5d1e44fefbc551c137aa503b3b07 116 Gene3D G3DSA:3.10.180.10 1 116 1.1E-12 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS40610 e84d5d1e44fefbc551c137aa503b3b07 116 SUPERFAMILY SSF54593 3 115 1.25E-7 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS32160 6ae6da6bd5e13d487762d6b0b7d38edf 256 SUPERFAMILY SSF52266 25 244 1.83E-52 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CU254_RS32160 6ae6da6bd5e13d487762d6b0b7d38edf 256 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 28 244 1.4E-20 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CU254_RS32160 6ae6da6bd5e13d487762d6b0b7d38edf 256 Gene3D G3DSA:3.40.50.1110 19 245 2.3E-34 T 28-03-2018 CU254_RS12860 714d5154621aba715635b04e8a98b7d2 121 Gene3D G3DSA:3.10.129.10 1 121 3.0E-24 T 28-03-2018 CU254_RS12860 714d5154621aba715635b04e8a98b7d2 121 SUPERFAMILY SSF54637 2 119 8.87E-20 T 28-03-2018 IPR029069 HotDog domain CU254_RS12860 714d5154621aba715635b04e8a98b7d2 121 Pfam PF13452 N-terminal half of MaoC dehydratase 5 103 4.0E-5 T 28-03-2018 CU254_RS03000 cf1a13d5b6d69a611d8019cc053c01b5 207 Gene3D G3DSA:3.40.50.2020 1 205 3.6E-59 T 28-03-2018 CU254_RS03000 cf1a13d5b6d69a611d8019cc053c01b5 207 Pfam PF14681 Uracil phosphoribosyltransferase 5 206 1.5E-59 T 28-03-2018 CU254_RS03000 cf1a13d5b6d69a611d8019cc053c01b5 207 SUPERFAMILY SSF53271 3 205 5.38E-57 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CU254_RS03000 cf1a13d5b6d69a611d8019cc053c01b5 207 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 3 206 1.7E-71 T 28-03-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CU254_RS03000 cf1a13d5b6d69a611d8019cc053c01b5 207 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 2 207 39.686 T 28-03-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CU254_RS38340 02b29b28645cd46791d372cf82d7ee4f 141 SUPERFAMILY SSF55729 17 131 2.23E-17 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS38340 02b29b28645cd46791d372cf82d7ee4f 141 Pfam PF13508 Acetyltransferase (GNAT) domain 55 127 3.9E-9 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS38340 02b29b28645cd46791d372cf82d7ee4f 141 Gene3D G3DSA:3.40.630.30 9 136 7.0E-18 T 28-03-2018 CU254_RS37445 136b46055439e11c519b00725b397f8e 376 SUPERFAMILY SSF53850 57 376 1.58E-85 T 28-03-2018 CU254_RS37445 136b46055439e11c519b00725b397f8e 376 Pfam PF12849 PBP superfamily domain 46 346 4.7E-59 T 28-03-2018 IPR024370 PBP domain CU254_RS37445 136b46055439e11c519b00725b397f8e 376 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 58 375 3.9E-85 T 28-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 CU254_RS37445 136b46055439e11c519b00725b397f8e 376 Gene3D G3DSA:3.40.190.10 228 376 5.5E-16 T 28-03-2018 CU254_RS37445 136b46055439e11c519b00725b397f8e 376 Gene3D G3DSA:3.40.190.10 56 227 1.3E-32 T 28-03-2018 CU254_RS37445 136b46055439e11c519b00725b397f8e 376 PIRSF PIRSF002756 8 376 6.4E-110 T 28-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 CU254_RS25695 aee3948cefcd4a145cd141d8877ee6d5 231 Gene3D G3DSA:3.40.30.10 24 231 3.1E-38 T 28-03-2018 CU254_RS25695 aee3948cefcd4a145cd141d8877ee6d5 231 Pfam PF01323 DSBA-like thioredoxin domain 25 222 1.0E-24 T 28-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 CU254_RS25695 aee3948cefcd4a145cd141d8877ee6d5 231 SUPERFAMILY SSF52833 24 227 5.85E-31 T 28-03-2018 IPR012336 Thioredoxin-like fold CU254_RS00060 e6dd706e149c6c424913715742257960 309 SUPERFAMILY SSF52151 24 232 2.28E-31 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CU254_RS00060 e6dd706e149c6c424913715742257960 309 Pfam PF01734 Patatin-like phospholipase 29 200 2.8E-17 T 28-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 CU254_RS00060 e6dd706e149c6c424913715742257960 309 Gene3D G3DSA:3.40.1090.10 17 230 1.7E-26 T 28-03-2018 CU254_RS15995 a9cbfca180a10836978db0cc7d758d23 403 Pfam PF05977 Transmembrane secretion effector 14 395 1.6E-25 T 28-03-2018 IPR010290 Transmembrane secretion effector CU254_RS15995 a9cbfca180a10836978db0cc7d758d23 403 Gene3D G3DSA:1.20.1250.20 3 197 8.9E-15 T 28-03-2018 CU254_RS15995 a9cbfca180a10836978db0cc7d758d23 403 Gene3D G3DSA:1.20.1250.20 206 400 1.2E-15 T 28-03-2018 CU254_RS15995 a9cbfca180a10836978db0cc7d758d23 403 SUPERFAMILY SSF103473 1 393 1.57E-42 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS08675 59ca295f29f25e712934a8a4bcdeea62 396 Pfam PF06772 Bacterial low temperature requirement A protein (LtrA) 31 385 2.3E-98 T 28-03-2018 IPR010640 Low temperature requirement A CU254_RS27460 04077982ad025ede65b0399845ca35a1 155 SMART SM00347 39 140 5.7E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS27460 04077982ad025ede65b0399845ca35a1 155 Pfam PF01047 MarR family 64 107 4.6E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS27460 04077982ad025ede65b0399845ca35a1 155 SUPERFAMILY SSF46785 17 140 1.85E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS27460 04077982ad025ede65b0399845ca35a1 155 Gene3D G3DSA:1.10.10.10 2 145 2.6E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS31490 4a885e4592c8a7a2262ac5d4353d83e8 184 SUPERFAMILY SSF55729 2 167 2.13E-38 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS31490 4a885e4592c8a7a2262ac5d4353d83e8 184 Gene3D G3DSA:3.40.630.30 2 184 4.6E-30 T 28-03-2018 CU254_RS31490 4a885e4592c8a7a2262ac5d4353d83e8 184 Pfam PF13302 Acetyltransferase (GNAT) domain 8 148 6.8E-31 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS27990 3ced1098e49c98f2695718b11b887f11 432 Gene3D G3DSA:2.130.10.10 38 432 0.0081 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CU254_RS19955 4d81ac01c48be4abecb353e76cae17d2 486 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 263 270 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CU254_RS19955 4d81ac01c48be4abecb353e76cae17d2 486 Gene3D G3DSA:3.40.605.10 5 279 1.4E-99 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CU254_RS19955 4d81ac01c48be4abecb353e76cae17d2 486 Pfam PF00171 Aldehyde dehydrogenase family 25 481 1.4E-161 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CU254_RS19955 4d81ac01c48be4abecb353e76cae17d2 486 Gene3D G3DSA:3.40.309.10 280 467 9.5E-68 T 28-03-2018 CU254_RS19955 4d81ac01c48be4abecb353e76cae17d2 486 SUPERFAMILY SSF53720 13 483 1.57E-161 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CU254_RS39505 ebcb44c305eb5db2c915e75819927073 495 Pfam PF01098 Cell cycle protein 88 457 3.0E-85 T 28-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 CU254_RS35775 32c0123cab88c704ce2b8fded5d61cf1 118 Gene3D G3DSA:3.30.70.1060 1 117 2.1E-32 T 28-03-2018 CU254_RS35775 32c0123cab88c704ce2b8fded5d61cf1 118 Pfam PF03795 YCII-related domain 1 113 5.7E-20 T 28-03-2018 IPR005545 YCII-related CU254_RS35775 32c0123cab88c704ce2b8fded5d61cf1 118 SUPERFAMILY SSF54909 1 114 5.2E-26 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS33250 d1070023d0b06857acb1101bc48911c4 189 SUPERFAMILY SSF48317 6 179 2.09E-34 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CU254_RS33250 d1070023d0b06857acb1101bc48911c4 189 Pfam PF01569 PAP2 superfamily 60 167 4.6E-21 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CU254_RS33250 d1070023d0b06857acb1101bc48911c4 189 SMART SM00014 52 167 4.8E-17 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CU254_RS33250 d1070023d0b06857acb1101bc48911c4 189 Gene3D G3DSA:1.20.144.10 7 180 1.4E-30 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CU254_RS38170 4adcd0c6dfe3e674b65d0448d7560a88 339 Pfam PF13407 Periplasmic binding protein domain 42 302 2.6E-52 T 28-03-2018 IPR025997 Periplasmic binding protein CU254_RS38170 4adcd0c6dfe3e674b65d0448d7560a88 339 SUPERFAMILY SSF53822 40 318 8.52E-62 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CU254_RS38170 4adcd0c6dfe3e674b65d0448d7560a88 339 Gene3D G3DSA:3.40.50.2300 155 312 1.2E-29 T 28-03-2018 CU254_RS38170 4adcd0c6dfe3e674b65d0448d7560a88 339 Gene3D G3DSA:3.40.50.2300 34 154 2.2E-21 T 28-03-2018 CU254_RS02990 5a4d0b6a588e0d640a1e5872350d22e9 210 Pfam PF09922 Cell wall-active antibiotics response 4TMS YvqF 101 169 5.9E-8 T 28-03-2018 IPR024425 Cell wall-active antibiotics response 4TMS YvqF CU254_RS02990 5a4d0b6a588e0d640a1e5872350d22e9 210 Pfam PF08044 Domain of unknown function (DUF1707) 1 53 1.6E-23 T 28-03-2018 IPR012551 Protein of unknown function DUF1707 CU254_RS02850 58ea88110bac283364c7eecaa4e3a22b 364 Gene3D G3DSA:3.90.20.10 206 315 8.8E-13 T 28-03-2018 CU254_RS02850 58ea88110bac283364c7eecaa4e3a22b 364 Gene3D G3DSA:1.20.120.330 46 205 1.3E-24 T 28-03-2018 CU254_RS02850 58ea88110bac283364c7eecaa4e3a22b 364 SUPERFAMILY SSF57997 72 256 7.19E-8 T 28-03-2018 CU254_RS18450 1891397a8922a2d02bb0164b339ce78a 324 Gene3D G3DSA:3.40.50.1820 6 324 1.4E-54 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS18450 1891397a8922a2d02bb0164b339ce78a 324 SUPERFAMILY SSF53474 44 321 1.34E-54 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS18450 1891397a8922a2d02bb0164b339ce78a 324 Pfam PF07859 alpha/beta hydrolase fold 92 297 7.1E-51 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CU254_RS17710 4f637b68eba582f2fd2ca1479fc049fa 319 SUPERFAMILY SSF161098 96 296 3.14E-13 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS17710 4f637b68eba582f2fd2ca1479fc049fa 319 Gene3D G3DSA:1.10.3720.10 5 299 5.9E-32 T 28-03-2018 CU254_RS17710 4f637b68eba582f2fd2ca1479fc049fa 319 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 120 310 1.1E-27 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS25770 56acbd90f64b1d2402a56b0f4c3a5227 179 Pfam PF10756 Bacterial PH domain 67 140 6.7E-5 T 28-03-2018 IPR019692 Protein of unknown function DUF2581 CU254_RS24070 300c5e358e7a9443d3d0436fdf552735 519 SUPERFAMILY SSF53850 32 385 2.65E-56 T 28-03-2018 CU254_RS24070 300c5e358e7a9443d3d0436fdf552735 519 Gene3D G3DSA:3.40.190.10 113 316 2.0E-34 T 28-03-2018 CU254_RS24070 300c5e358e7a9443d3d0436fdf552735 519 Pfam PF12849 PBP superfamily domain 25 324 5.7E-40 T 28-03-2018 IPR024370 PBP domain CU254_RS40445 aab8c9a0688c399ba0a78c7fafd5188f 383 Gene3D G3DSA:3.40.50.1820 2 383 1.1E-81 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS40445 aab8c9a0688c399ba0a78c7fafd5188f 383 PRINTS PR00412 Epoxide hydrolase signature 189 202 3.7E-15 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS40445 aab8c9a0688c399ba0a78c7fafd5188f 383 PRINTS PR00412 Epoxide hydrolase signature 356 378 3.7E-15 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS40445 aab8c9a0688c399ba0a78c7fafd5188f 383 PRINTS PR00412 Epoxide hydrolase signature 101 119 3.7E-15 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS40445 aab8c9a0688c399ba0a78c7fafd5188f 383 PRINTS PR00412 Epoxide hydrolase signature 175 188 3.7E-15 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS40445 aab8c9a0688c399ba0a78c7fafd5188f 383 PRINTS PR00412 Epoxide hydrolase signature 130 145 3.7E-15 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS40445 aab8c9a0688c399ba0a78c7fafd5188f 383 PRINTS PR00412 Epoxide hydrolase signature 325 341 3.7E-15 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CU254_RS40445 aab8c9a0688c399ba0a78c7fafd5188f 383 SUPERFAMILY SSF53474 3 381 3.04E-103 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS40445 aab8c9a0688c399ba0a78c7fafd5188f 383 Pfam PF06441 Epoxide hydrolase N terminus 6 110 3.4E-37 T 28-03-2018 IPR010497 Epoxide hydrolase, N-terminal KEGG: 00980+3.3.2.9|Reactome: R-HSA-211945 CU254_RS40445 aab8c9a0688c399ba0a78c7fafd5188f 383 PIRSF PIRSF001112 1 382 3.2E-121 T 28-03-2018 IPR016292 Epoxide hydrolase GO:0033961 KEGG: 00980+3.3.2.9|Reactome: R-HSA-211945 CU254_RS06360 2bb650cb6edc9d39a19c28c7f4983143 321 Gene3D G3DSA:2.40.10.10 190 321 8.9E-21 T 28-03-2018 CU254_RS06360 2bb650cb6edc9d39a19c28c7f4983143 321 SUPERFAMILY SSF50494 55 282 1.98E-15 T 28-03-2018 IPR009003 Peptidase S1, PA clan CU254_RS06360 2bb650cb6edc9d39a19c28c7f4983143 321 Gene3D G3DSA:2.40.10.10 74 189 2.8E-9 T 28-03-2018 CU254_RS12460 3c87ce60f93b9a024fe7d2035ce0d92d 274 Gene3D G3DSA:3.40.50.720 107 237 7.6E-9 T 28-03-2018 CU254_RS12460 3c87ce60f93b9a024fe7d2035ce0d92d 274 SUPERFAMILY SSF51735 74 205 1.41E-5 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS12460 3c87ce60f93b9a024fe7d2035ce0d92d 274 Pfam PF13478 XdhC Rossmann domain 109 258 5.2E-34 T 28-03-2018 IPR027051 XdhC Rossmann domain CU254_RS12460 3c87ce60f93b9a024fe7d2035ce0d92d 274 Pfam PF02625 XdhC and CoxI family 11 73 1.4E-15 T 28-03-2018 IPR003777 XdhC- CoxI CU254_RS12460 3c87ce60f93b9a024fe7d2035ce0d92d 274 TIGRFAM TIGR02964 xanthine_xdhC: xanthine dehydrogenase accessory protein XdhC 18 260 6.0E-75 T 28-03-2018 IPR014308 Xanthine dehydrogenase accessory protein XdhC CU254_RS40940 a2b7249228349a12b0fb42c73b4b8070 298 Gene3D G3DSA:1.10.260.40 22 88 2.3E-7 T 28-03-2018 CU254_RS40940 a2b7249228349a12b0fb42c73b4b8070 298 SUPERFAMILY SSF47413 19 73 5.33E-6 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS40940 a2b7249228349a12b0fb42c73b4b8070 298 Pfam PF10901 Protein of unknown function (DUF2690) 167 259 3.9E-14 T 28-03-2018 IPR021224 Protein of unknown function DUF2690 CU254_RS40940 a2b7249228349a12b0fb42c73b4b8070 298 SMART SM00530 22 81 0.0012 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS40940 a2b7249228349a12b0fb42c73b4b8070 298 Pfam PF13560 Helix-turn-helix domain 19 71 5.9E-10 T 28-03-2018 CU254_RS26285 d1e6beec67414e626c78de235befbe94 191 Gene3D G3DSA:3.40.50.150 1 185 5.7E-25 T 28-03-2018 CU254_RS26285 d1e6beec67414e626c78de235befbe94 191 SUPERFAMILY SSF53335 11 167 2.55E-27 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS26285 d1e6beec67414e626c78de235befbe94 191 Pfam PF13489 Methyltransferase domain 24 125 2.7E-15 T 28-03-2018 CU254_RS22800 0130b295e8c6e252a734e86083b34b99 504 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 62 222 2.2E-18 T 28-03-2018 CU254_RS24755 bad8ad4f0b5d2fd08a23e3d2463e592d 682 SUPERFAMILY SSF52266 461 492 9.16E-5 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CU254_RS24755 bad8ad4f0b5d2fd08a23e3d2463e592d 682 SUPERFAMILY SSF52266 526 680 9.16E-5 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CU254_RS24755 bad8ad4f0b5d2fd08a23e3d2463e592d 682 Gene3D G3DSA:3.40.50.1110 457 680 7.6E-8 T 28-03-2018 CU254_RS24755 bad8ad4f0b5d2fd08a23e3d2463e592d 682 Pfam PF01757 Acyltransferase family 27 356 7.1E-18 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CU254_RS39980 c1e679cc43242f23443fedeebe4be515 117 SUPERFAMILY SSF56399 2 113 5.18E-29 T 28-03-2018 CU254_RS39980 c1e679cc43242f23443fedeebe4be515 117 Pfam PF06108 Protein of unknown function (DUF952) 5 97 2.6E-27 T 28-03-2018 IPR009297 Protein of unknown function DUF952 CU254_RS21220 6d45d1aa5bd6a58d5b19988b9121a6a6 289 SUPERFAMILY SSF51679 4 284 1.23E-57 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS21220 6d45d1aa5bd6a58d5b19988b9121a6a6 289 Gene3D G3DSA:3.20.20.30 2 288 2.4E-58 T 28-03-2018 CU254_RS21220 6d45d1aa5bd6a58d5b19988b9121a6a6 289 Pfam PF00296 Luciferase-like monooxygenase 12 245 9.6E-43 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS38130 22ee76a9951ecf27d314258fdfe58c3a 225 Pfam PF09335 SNARE associated Golgi protein 47 174 8.1E-21 T 28-03-2018 IPR032816 SNARE associated Golgi protein CU254_RS31605 c62e30c6b82e5357387b7d3b2c98f533 244 PIRSF PIRSF006648 1 244 3.0E-17 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CU254_RS31605 c62e30c6b82e5357387b7d3b2c98f533 244 Pfam PF01061 ABC-2 type transporter 8 206 6.5E-32 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CU254_RS18090 ecf224ba4d870bf5f0aec8f26cb344be 465 Gene3D G3DSA:3.40.50.300 27 329 3.3E-16 T 28-03-2018 CU254_RS18090 ecf224ba4d870bf5f0aec8f26cb344be 465 Pfam PF00158 Sigma-54 interaction domain 171 229 1.4E-5 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CU254_RS18090 ecf224ba4d870bf5f0aec8f26cb344be 465 SUPERFAMILY SSF52540 44 321 2.01E-27 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS03305 cbd63c33cb588b7ad562396284627dc1 271 Gene3D G3DSA:1.10.260.40 2 70 9.8E-6 T 28-03-2018 CU254_RS03305 cbd63c33cb588b7ad562396284627dc1 271 Pfam PF16158 Ig-like domain from next to BRCA1 gene 166 267 4.0E-14 T 28-03-2018 IPR032350 Next to BRCA1, central domain CU254_RS03305 cbd63c33cb588b7ad562396284627dc1 271 Pfam PF13560 Helix-turn-helix domain 11 72 1.7E-6 T 28-03-2018 CU254_RS22935 15a42e3fc2b8bfaddf3f0cba88634a21 486 Gene3D G3DSA:3.90.350.10 81 372 1.5E-16 T 28-03-2018 IPR014736 Transposase, Tn5-like, core CU254_RS22935 15a42e3fc2b8bfaddf3f0cba88634a21 486 SUPERFAMILY SSF53098 49 394 7.36E-11 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS22935 15a42e3fc2b8bfaddf3f0cba88634a21 486 Pfam PF13546 DDE superfamily endonuclease 22 285 9.9E-52 T 28-03-2018 CU254_RS29545 a0c87328adbb8e8374358efe6ba1f134 317 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 3 308 3.5E-104 T 28-03-2018 IPR019949 Luciferase family oxidoreductase, group 1 CU254_RS29545 a0c87328adbb8e8374358efe6ba1f134 317 Pfam PF00296 Luciferase-like monooxygenase 7 285 2.3E-33 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS29545 a0c87328adbb8e8374358efe6ba1f134 317 SUPERFAMILY SSF51679 1 307 3.14E-70 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS29545 a0c87328adbb8e8374358efe6ba1f134 317 Gene3D G3DSA:3.20.20.30 7 309 2.4E-68 T 28-03-2018 CU254_RS00015 3dca77eb4b7eaf6800584bcaa3964197 157 Gene3D G3DSA:2.60.40.1120 63 155 1.8E-5 T 28-03-2018 CU254_RS31070 532badc5b17852b87c1e743c51d3cd29 245 PRINTS PR00111 Alpha/beta hydrolase fold signature 89 102 2.4E-12 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS31070 532badc5b17852b87c1e743c51d3cd29 245 PRINTS PR00111 Alpha/beta hydrolase fold signature 75 88 2.4E-12 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS31070 532badc5b17852b87c1e743c51d3cd29 245 PRINTS PR00111 Alpha/beta hydrolase fold signature 190 204 2.4E-12 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS31070 532badc5b17852b87c1e743c51d3cd29 245 PRINTS PR00111 Alpha/beta hydrolase fold signature 29 44 2.4E-12 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS31070 532badc5b17852b87c1e743c51d3cd29 245 Gene3D G3DSA:3.40.50.1820 2 245 2.2E-49 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS31070 532badc5b17852b87c1e743c51d3cd29 245 SUPERFAMILY SSF53474 5 244 1.58E-58 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS31070 532badc5b17852b87c1e743c51d3cd29 245 Pfam PF12697 Alpha/beta hydrolase family 6 239 6.0E-25 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS25150 10c790a704c8748d5bdcda07d6873752 112 Gene3D G3DSA:1.10.287.1060 3 99 1.2E-17 T 28-03-2018 CU254_RS25150 10c790a704c8748d5bdcda07d6873752 112 Pfam PF06013 Proteins of 100 residues with WXG 8 90 1.8E-16 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CU254_RS25150 10c790a704c8748d5bdcda07d6873752 112 SUPERFAMILY SSF140453 8 96 1.29E-17 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CU254_RS25150 10c790a704c8748d5bdcda07d6873752 112 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 8 94 2.3E-18 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CU254_RS00540 4cd0bd32fa352c6b6d8fa5bf21670428 135 SUPERFAMILY SSF54637 3 132 3.38E-34 T 28-03-2018 IPR029069 HotDog domain CU254_RS00540 4cd0bd32fa352c6b6d8fa5bf21670428 135 Pfam PF03061 Thioesterase superfamily 20 102 1.8E-11 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CU254_RS00540 4cd0bd32fa352c6b6d8fa5bf21670428 135 Gene3D G3DSA:3.10.129.10 2 134 5.2E-32 T 28-03-2018 CU254_RS07050 b564960a25e7ddf71f77cacfa96e04ac 294 Gene3D G3DSA:3.40.1130.10 63 279 6.7E-45 T 28-03-2018 CU254_RS07050 b564960a25e7ddf71f77cacfa96e04ac 294 SMART SM00563 86 204 1.2E-29 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CU254_RS07050 b564960a25e7ddf71f77cacfa96e04ac 294 Pfam PF01553 Acyltransferase 76 200 1.5E-22 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CU254_RS07050 b564960a25e7ddf71f77cacfa96e04ac 294 SUPERFAMILY SSF69593 63 268 1.57E-40 T 28-03-2018 CU254_RS16245 36e12be342017db6944e9a56ba825187 218 SUPERFAMILY SSF51735 3 217 2.82E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS16245 36e12be342017db6944e9a56ba825187 218 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.4E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS16245 36e12be342017db6944e9a56ba825187 218 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 61 72 1.4E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS16245 36e12be342017db6944e9a56ba825187 218 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 203 1.4E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS16245 36e12be342017db6944e9a56ba825187 218 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 164 1.4E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS16245 36e12be342017db6944e9a56ba825187 218 Gene3D G3DSA:3.40.50.720 1 218 1.5E-39 T 28-03-2018 CU254_RS16245 36e12be342017db6944e9a56ba825187 218 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 216 5.3E-18 T 28-03-2018 CU254_RS08440 3645826cbf6b4cab86507bccd0a4b918 247 Pfam PF03883 Peroxide stress protein YaaA 2 232 2.1E-38 T 28-03-2018 IPR005583 Peroxide stress protein YaaA CU254_RS08440 3645826cbf6b4cab86507bccd0a4b918 247 Gene3D G3DSA:3.40.220.10 165 237 9.7E-4 T 28-03-2018 CU254_RS37140 e7a39e10eb49dc2bbfca6d1682dc07e3 589 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 67 225 1.2E-29 T 28-03-2018 CU254_RS06070 8300a2d350a5ade6fdbe7c6bd4f0131a 253 Gene3D G3DSA:1.20.1250.20 3 76 0.0071 T 28-03-2018 CU254_RS28140 1c2400717bc7eb391ada29020d768ff8 306 SUPERFAMILY SSF63829 3 221 1.19E-46 T 28-03-2018 CU254_RS28140 1c2400717bc7eb391ada29020d768ff8 306 SUPERFAMILY SSF63829 253 300 1.19E-46 T 28-03-2018 CU254_RS28140 1c2400717bc7eb391ada29020d768ff8 306 Gene3D G3DSA:2.120.10.30 6 306 1.5E-36 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CU254_RS28140 1c2400717bc7eb391ada29020d768ff8 306 Pfam PF03088 Strictosidine synthase 106 187 3.4E-16 T 28-03-2018 IPR018119 Strictosidine synthase, conserved region GO:0009058|GO:0016844 CU254_RS20025 13391bacb8ee413578e2bdb020537fe7 173 SUPERFAMILY SSF53597 4 165 2.36E-25 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CU254_RS20025 13391bacb8ee413578e2bdb020537fe7 173 Gene3D G3DSA:3.40.430.10 2 173 2.8E-36 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CU254_RS20025 13391bacb8ee413578e2bdb020537fe7 173 Pfam PF01872 RibD C-terminal domain 4 159 3.1E-19 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CU254_RS02635 02ed793ac1e0df613f9d85528800ca19 197 Gene3D G3DSA:3.40.50.300 22 124 6.3E-8 T 28-03-2018 CU254_RS36665 638508eea7d128a8a21c90f0553d54c7 404 Pfam PF01474 Class-II DAHP synthetase family 189 397 4.9E-71 T 28-03-2018 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CU254_RS36665 638508eea7d128a8a21c90f0553d54c7 404 SUPERFAMILY SSF51569 19 401 4.1E-132 T 28-03-2018 CU254_RS02610 0c21e2a20c7ca46b40e4788b24f0ec08 205 Gene3D G3DSA:3.40.50.170 2 203 3.3E-65 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CU254_RS02610 0c21e2a20c7ca46b40e4788b24f0ec08 205 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 8 193 29.479 T 28-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 CU254_RS02610 0c21e2a20c7ca46b40e4788b24f0ec08 205 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 8 192 9.3E-69 T 28-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 CU254_RS02610 0c21e2a20c7ca46b40e4788b24f0ec08 205 Pfam PF00551 Formyl transferase 8 187 1.8E-50 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CU254_RS02610 0c21e2a20c7ca46b40e4788b24f0ec08 205 SUPERFAMILY SSF53328 8 201 1.26E-58 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CU254_RS02610 0c21e2a20c7ca46b40e4788b24f0ec08 205 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 139 162 - T 28-03-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CU254_RS37695 39f85269561b037f539f1865f533753d 270 SUPERFAMILY SSF53335 54 213 3.88E-17 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS37695 39f85269561b037f539f1865f533753d 270 Pfam PF13649 Methyltransferase domain 63 143 4.9E-6 T 28-03-2018 CU254_RS37695 39f85269561b037f539f1865f533753d 270 Gene3D G3DSA:3.40.50.150 43 225 1.9E-14 T 28-03-2018 CU254_RS25250 bc27a2bc76925491adaa8cc1619bdeb8 107 SUPERFAMILY SSF53474 8 104 1.79E-12 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS25250 bc27a2bc76925491adaa8cc1619bdeb8 107 Gene3D G3DSA:3.40.50.1820 1 104 2.3E-7 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS12000 bd7f2c1145b745caf048f98c328ce670 203 Pfam PF06314 Acetoacetate decarboxylase (ADC) 12 120 3.8E-14 T 28-03-2018 IPR010451 Acetoacetate decarboxylase GO:0016829 KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 CU254_RS12000 bd7f2c1145b745caf048f98c328ce670 203 SUPERFAMILY SSF160104 4 160 7.32E-24 T 28-03-2018 IPR023375 Acetoacetate decarboxylase beta barrel domain KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 CU254_RS12000 bd7f2c1145b745caf048f98c328ce670 203 Gene3D G3DSA:2.40.400.10 2 188 2.0E-26 T 28-03-2018 IPR023375 Acetoacetate decarboxylase beta barrel domain KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 CU254_RS09340 0920a2ffec3eae8e8f5900d10783b093 142 Pfam PF05685 Putative restriction endonuclease 2 140 1.4E-16 T 28-03-2018 IPR008538 Domain of unknown function DUF820 CU254_RS09340 0920a2ffec3eae8e8f5900d10783b093 142 SUPERFAMILY SSF52980 3 129 1.66E-13 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CU254_RS09340 0920a2ffec3eae8e8f5900d10783b093 142 Gene3D G3DSA:3.90.1570.10 1 141 4.4E-18 T 28-03-2018 CU254_RS40305 5ec84667b3c76c9f9d2c800eae48840f 266 Gene3D G3DSA:3.40.50.1000 1 266 1.4E-36 T 28-03-2018 IPR023214 HAD-like domain CU254_RS40305 5ec84667b3c76c9f9d2c800eae48840f 266 Pfam PF08282 haloacid dehalogenase-like hydrolase 2 262 5.7E-54 T 28-03-2018 IPR023214 HAD-like domain CU254_RS40305 5ec84667b3c76c9f9d2c800eae48840f 266 SUPERFAMILY SSF56784 1 266 3.64E-55 T 28-03-2018 IPR023214 HAD-like domain CU254_RS40305 5ec84667b3c76c9f9d2c800eae48840f 266 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 1 262 3.3E-44 T 28-03-2018 IPR000150 Cof family GO:0016787 CU254_RS40305 5ec84667b3c76c9f9d2c800eae48840f 266 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 1 235 2.2E-24 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CU254_RS21095 a9bc1b894fd561a756629f87ce08bfc8 90 Pfam PF05402 Coenzyme PQQ synthesis protein D (PqqD) 27 87 5.0E-8 T 28-03-2018 IPR008792 Coenzyme PQQ synthesis D CU254_RS21095 a9bc1b894fd561a756629f87ce08bfc8 90 TIGRFAM TIGR03859 PQQ_PqqD: coenzyme PQQ biosynthesis protein PqqD 10 88 2.3E-19 T 28-03-2018 IPR022479 Coenzyme PQQ synthesis D, bacteria GO:0018189|GO:0048038 CU254_RS18935 5041b71718ce5a593a835a0372ced490 456 Gene3D G3DSA:3.20.20.70 146 403 7.9E-13 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS18935 5041b71718ce5a593a835a0372ced490 456 SUPERFAMILY SSF102114 148 406 1.73E-12 T 28-03-2018 CU254_RS07250 8b13250e2bb1b90bb821d3ae73aec535 401 Pfam PF02470 MlaD protein 39 114 3.2E-12 T 28-03-2018 IPR003399 Mce/MlaD CU254_RS07250 8b13250e2bb1b90bb821d3ae73aec535 401 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 10 297 2.5E-56 T 28-03-2018 IPR005693 Virulence factor Mce protein CU254_RS37270 9785cdf2bc41bde61f3784b66a45f41f 221 PRINTS PR00111 Alpha/beta hydrolase fold signature 80 93 8.5E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS37270 9785cdf2bc41bde61f3784b66a45f41f 221 PRINTS PR00111 Alpha/beta hydrolase fold signature 25 40 8.5E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS37270 9785cdf2bc41bde61f3784b66a45f41f 221 PRINTS PR00111 Alpha/beta hydrolase fold signature 66 79 8.5E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS37270 9785cdf2bc41bde61f3784b66a45f41f 221 Gene3D G3DSA:3.40.50.1820 2 217 1.5E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS37270 9785cdf2bc41bde61f3784b66a45f41f 221 Pfam PF12697 Alpha/beta hydrolase family 4 214 7.3E-21 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS37270 9785cdf2bc41bde61f3784b66a45f41f 221 SUPERFAMILY SSF53474 3 215 3.16E-32 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS11875 643123ff94391c21dbbdc9507843cdcd 368 SUPERFAMILY SSF51905 226 286 8.29E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS11875 643123ff94391c21dbbdc9507843cdcd 368 SUPERFAMILY SSF51905 1 161 8.29E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS11875 643123ff94391c21dbbdc9507843cdcd 368 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 178 203 9.4E-6 T 28-03-2018 CU254_RS11875 643123ff94391c21dbbdc9507843cdcd 368 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 9.4E-6 T 28-03-2018 CU254_RS11875 643123ff94391c21dbbdc9507843cdcd 368 Gene3D G3DSA:3.50.50.60 1 341 8.7E-19 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS11875 643123ff94391c21dbbdc9507843cdcd 368 TIGRFAM TIGR01790 carotene-cycl: lycopene cyclase family protein 3 364 1.4E-63 T 28-03-2018 IPR010108 Lycopene cyclase, beta/epsilon GO:0016117|GO:0016705 CU254_RS11875 643123ff94391c21dbbdc9507843cdcd 368 Pfam PF05834 Lycopene cyclase protein 3 359 9.3E-54 T 28-03-2018 CU254_RS11595 1ad04dcd20ca4c33522c7577c5b7cf25 201 PIRSF PIRSF000498 1 201 1.8E-68 T 28-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CU254_RS11595 1ad04dcd20ca4c33522c7577c5b7cf25 201 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 2 189 1.3E-59 T 28-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CU254_RS11595 1ad04dcd20ca4c33522c7577c5b7cf25 201 SUPERFAMILY SSF63380 92 192 4.85E-30 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CU254_RS11595 1ad04dcd20ca4c33522c7577c5b7cf25 201 Gene3D G3DSA:2.40.30.20 1 92 2.9E-27 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CU254_RS11595 1ad04dcd20ca4c33522c7577c5b7cf25 201 Gene3D G3DSA:2.40.30.20 93 187 1.3E-32 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CU254_RS11595 1ad04dcd20ca4c33522c7577c5b7cf25 201 Pfam PF00677 Lumazine binding domain 3 86 5.5E-22 T 28-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CU254_RS11595 1ad04dcd20ca4c33522c7577c5b7cf25 201 Pfam PF00677 Lumazine binding domain 99 180 2.7E-24 T 28-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CU254_RS11595 1ad04dcd20ca4c33522c7577c5b7cf25 201 SUPERFAMILY SSF63380 2 87 9.35E-24 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CU254_RS16320 8fee303f4f4262d8c42158e43bb4ecd9 277 Gene3D G3DSA:3.20.20.70 43 258 2.8E-30 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS16320 8fee303f4f4262d8c42158e43bb4ecd9 277 SUPERFAMILY SSF51445 54 251 7.79E-18 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS16320 8fee303f4f4262d8c42158e43bb4ecd9 277 Pfam PF03537 Glycoside-hydrolase family GH114 53 265 1.2E-46 T 28-03-2018 IPR004352 Glycoside-hydrolase family GH114, TIM-barrel domain CU254_RS34455 6fbaa171c3f500e07533429ca9a32d8d 388 Pfam PF02515 CoA-transferase family III 7 372 3.2E-88 T 28-03-2018 IPR003673 CoA-transferase family III GO:0003824 CU254_RS34455 6fbaa171c3f500e07533429ca9a32d8d 388 Gene3D G3DSA:3.40.50.10540 1 387 4.1E-103 T 28-03-2018 IPR023606 CoA-transferase family III domain CU254_RS34455 6fbaa171c3f500e07533429ca9a32d8d 388 SUPERFAMILY SSF89796 2 382 1.57E-98 T 28-03-2018 IPR023606 CoA-transferase family III domain CU254_RS37540 becaf2e43e99358a3a46eab998b02ec4 60 Pfam PF11273 Protein of unknown function (DUF3073) 2 59 8.7E-24 T 28-03-2018 IPR021426 Protein of unknown function DUF3073 CU254_RS06210 76111121816e39ab00b28cd7919b439e 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 58 2.1E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS06210 76111121816e39ab00b28cd7919b439e 199 Gene3D G3DSA:1.10.357.10 59 199 1.7E-19 T 28-03-2018 CU254_RS06210 76111121816e39ab00b28cd7919b439e 199 SUPERFAMILY SSF46689 2 82 1.55E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS06210 76111121816e39ab00b28cd7919b439e 199 SUPERFAMILY SSF48498 79 197 1.28E-17 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS06210 76111121816e39ab00b28cd7919b439e 199 Gene3D G3DSA:1.10.10.60 1 58 2.5E-19 T 28-03-2018 CU254_RS06210 76111121816e39ab00b28cd7919b439e 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 1.0E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS06210 76111121816e39ab00b28cd7919b439e 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 1.0E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS13530 5f061fe20db5a6f0b977e0bf14501c5a 123 Pfam PF03795 YCII-related domain 2 117 6.1E-18 T 28-03-2018 IPR005545 YCII-related CU254_RS13530 5f061fe20db5a6f0b977e0bf14501c5a 123 Gene3D G3DSA:3.30.70.1060 1 121 1.4E-35 T 28-03-2018 CU254_RS13530 5f061fe20db5a6f0b977e0bf14501c5a 123 SUPERFAMILY SSF54909 3 119 2.12E-27 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS00690 ac3c7bc922b0985cc4522040b43a378f 373 Gene3D G3DSA:3.20.20.210 1 373 1.1E-95 T 28-03-2018 CU254_RS00690 ac3c7bc922b0985cc4522040b43a378f 373 SUPERFAMILY SSF51726 9 371 8.76E-77 T 28-03-2018 CU254_RS00690 ac3c7bc922b0985cc4522040b43a378f 373 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 164 345 9.5E-6 T 28-03-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CU254_RS42125 a91612bae1a2d296a76ac5f474441174 454 SUPERFAMILY SSF53383 5 452 2.55E-98 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS42125 a91612bae1a2d296a76ac5f474441174 454 Gene3D G3DSA:3.90.1150.10 18 146 6.6E-22 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS42125 a91612bae1a2d296a76ac5f474441174 454 Gene3D G3DSA:3.90.1150.10 268 451 3.0E-60 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS42125 a91612bae1a2d296a76ac5f474441174 454 Pfam PF01212 Beta-eliminating lyase 46 418 1.0E-62 T 28-03-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 CU254_RS27035 d5a040ecd603ac0392bfb01b38502638 201 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 113 126 - T 28-03-2018 IPR033135 ClpP, histidine active site CU254_RS27035 d5a040ecd603ac0392bfb01b38502638 201 PRINTS PR00127 Clp protease catalytic subunit P signature 169 188 9.1E-44 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CU254_RS27035 d5a040ecd603ac0392bfb01b38502638 201 PRINTS PR00127 Clp protease catalytic subunit P signature 60 80 9.1E-44 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CU254_RS27035 d5a040ecd603ac0392bfb01b38502638 201 PRINTS PR00127 Clp protease catalytic subunit P signature 91 108 9.1E-44 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CU254_RS27035 d5a040ecd603ac0392bfb01b38502638 201 PRINTS PR00127 Clp protease catalytic subunit P signature 112 131 9.1E-44 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CU254_RS27035 d5a040ecd603ac0392bfb01b38502638 201 PRINTS PR00127 Clp protease catalytic subunit P signature 20 35 9.1E-44 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CU254_RS27035 d5a040ecd603ac0392bfb01b38502638 201 Gene3D G3DSA:3.90.226.10 22 194 1.1E-40 T 28-03-2018 CU254_RS27035 d5a040ecd603ac0392bfb01b38502638 201 SUPERFAMILY SSF52096 21 194 7.4E-65 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS27035 d5a040ecd603ac0392bfb01b38502638 201 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 4 194 38.896 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CU254_RS27035 d5a040ecd603ac0392bfb01b38502638 201 Pfam PF00574 Clp protease 19 193 2.5E-74 T 28-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA CU254_RS28740 e6afbc22a3717fe07467e85bdab47a14 493 Gene3D G3DSA:2.60.40.1310 130 233 0.054 T 28-03-2018 CU254_RS28740 e6afbc22a3717fe07467e85bdab47a14 493 Gene3D G3DSA:2.60.40.1310 234 347 0.065 T 28-03-2018 CU254_RS40380 864e87e5a098d00f1b1cedc515a01a2a 142 Pfam PF04138 GtrA-like protein 13 134 3.6E-18 T 28-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 CU254_RS34695 88c44d939e54e62e60142d722d59eb89 388 Gene3D G3DSA:3.60.120.10 45 384 1.0E-98 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CU254_RS34695 88c44d939e54e62e60142d722d59eb89 388 Pfam PF00425 chorismate binding enzyme 119 373 4.3E-75 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal CU254_RS34695 88c44d939e54e62e60142d722d59eb89 388 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 114 379 5.9E-85 T 28-03-2018 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 CU254_RS34695 88c44d939e54e62e60142d722d59eb89 388 SUPERFAMILY SSF56322 27 383 8.24E-91 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CU254_RS41060 0af0ab72867930849b30accf0de55654 338 Pfam PF14040 Deoxyribonuclease NucA/NucB 248 334 8.2E-14 T 28-03-2018 IPR029476 Deoxyribonuclease NucA/NucB CU254_RS22130 323bed8e6c3b3c782089797c17121683 361 Gene3D G3DSA:3.40.50.300 54 258 3.0E-20 T 28-03-2018 CU254_RS22130 323bed8e6c3b3c782089797c17121683 361 SUPERFAMILY SSF52540 57 260 3.32E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS22130 323bed8e6c3b3c782089797c17121683 361 Pfam PF07728 AAA domain (dynein-related subfamily) 79 217 3.7E-37 T 28-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 CU254_RS32030 e2131b0aae6b9e3b62ac5a2cab5ea8af 151 Pfam PF12587 Protein of unknown function (DUF3761) 100 151 3.9E-21 T 28-03-2018 IPR022236 Protein of unknown function DUF3761 CU254_RS42240 d085363d64207447e8fbbd9d14789397 281 SUPERFAMILY SSF56112 105 238 9.18E-7 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS42240 d085363d64207447e8fbbd9d14789397 281 Gene3D G3DSA:3.90.1200.10 3 248 4.0E-7 T 28-03-2018 CU254_RS31870 2d90f25f0aaefe5bcc12238c23b1bd57 483 PIRSF PIRSF026631 1 471 4.9E-63 T 28-03-2018 IPR014529 Uncharacterised conserved protein UCP026631 CU254_RS31870 2d90f25f0aaefe5bcc12238c23b1bd57 483 Pfam PF03703 Bacterial PH domain 390 462 1.2E-9 T 28-03-2018 IPR005182 Domain of unknown function DUF304 CU254_RS31870 2d90f25f0aaefe5bcc12238c23b1bd57 483 Pfam PF03703 Bacterial PH domain 51 132 3.8E-8 T 28-03-2018 IPR005182 Domain of unknown function DUF304 CU254_RS29910 caa1f11ea7c0dbbe636e4f5948977a33 140 SUPERFAMILY SSF46785 3 135 1.43E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS29910 caa1f11ea7c0dbbe636e4f5948977a33 140 Pfam PF01475 Ferric uptake regulator family 11 102 8.0E-15 T 28-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CU254_RS29910 caa1f11ea7c0dbbe636e4f5948977a33 140 Gene3D G3DSA:1.10.10.10 4 90 1.0E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS20575 f8013c46c72ca3ff8706f0b7a91deceb 129 SUPERFAMILY SSF54427 2 105 5.09E-24 T 28-03-2018 IPR032710 NTF2-like domain CU254_RS20575 f8013c46c72ca3ff8706f0b7a91deceb 129 Gene3D G3DSA:3.10.450.50 1 129 5.0E-20 T 28-03-2018 CU254_RS20575 f8013c46c72ca3ff8706f0b7a91deceb 129 Pfam PF12680 SnoaL-like domain 4 96 1.8E-7 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CU254_RS06905 3043509841e65c0122fe68439413967a 208 Pfam PF07077 Protein of unknown function (DUF1345) 32 198 6.4E-39 T 28-03-2018 IPR009781 Protein of unknown function DUF1345 CU254_RS07145 fb931667d54f481261b38bdd0cba7e67 262 Pfam PF12697 Alpha/beta hydrolase family 25 254 1.3E-13 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS07145 fb931667d54f481261b38bdd0cba7e67 262 SUPERFAMILY SSF53474 4 261 1.55E-31 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS07145 fb931667d54f481261b38bdd0cba7e67 262 Gene3D G3DSA:3.40.50.1820 1 262 2.7E-39 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS14125 3fe72f74596cb18360d72039216fd723 341 SUPERFAMILY SSF51735 120 296 1.69E-30 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS14125 3fe72f74596cb18360d72039216fd723 341 SMART SM00829 10 338 7.1E-12 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CU254_RS14125 3fe72f74596cb18360d72039216fd723 341 SUPERFAMILY SSF50129 2 141 1.23E-33 T 28-03-2018 IPR011032 GroES-like CU254_RS14125 3fe72f74596cb18360d72039216fd723 341 Gene3D G3DSA:3.90.180.10 1 162 6.3E-45 T 28-03-2018 CU254_RS14125 3fe72f74596cb18360d72039216fd723 341 Gene3D G3DSA:3.40.50.720 163 276 2.5E-20 T 28-03-2018 CU254_RS14125 3fe72f74596cb18360d72039216fd723 341 Pfam PF00107 Zinc-binding dehydrogenase 166 277 3.2E-20 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CU254_RS14125 3fe72f74596cb18360d72039216fd723 341 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 88 1.7E-5 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CU254_RS25965 0126aad5c6bec5e1e56f2eb2f13b9239 417 Gene3D G3DSA:3.20.20.70 33 309 2.6E-100 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS25965 0126aad5c6bec5e1e56f2eb2f13b9239 417 ProSitePatterns PS00512 Alpha-galactosidase signature. 76 92 - T 28-03-2018 IPR000111 Glycoside hydrolase family 27/36, conserved site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CU254_RS25965 0126aad5c6bec5e1e56f2eb2f13b9239 417 Pfam PF16499 Alpha galactosidase A 40 312 2.7E-77 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CU254_RS25965 0126aad5c6bec5e1e56f2eb2f13b9239 417 PRINTS PR00740 Glycosyl hydrolase family 27 signature 247 266 3.0E-50 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CU254_RS25965 0126aad5c6bec5e1e56f2eb2f13b9239 417 PRINTS PR00740 Glycosyl hydrolase family 27 signature 182 200 3.0E-50 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CU254_RS25965 0126aad5c6bec5e1e56f2eb2f13b9239 417 PRINTS PR00740 Glycosyl hydrolase family 27 signature 35 54 3.0E-50 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CU254_RS25965 0126aad5c6bec5e1e56f2eb2f13b9239 417 PRINTS PR00740 Glycosyl hydrolase family 27 signature 268 289 3.0E-50 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CU254_RS25965 0126aad5c6bec5e1e56f2eb2f13b9239 417 PRINTS PR00740 Glycosyl hydrolase family 27 signature 71 86 3.0E-50 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CU254_RS25965 0126aad5c6bec5e1e56f2eb2f13b9239 417 PRINTS PR00740 Glycosyl hydrolase family 27 signature 153 170 3.0E-50 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CU254_RS25965 0126aad5c6bec5e1e56f2eb2f13b9239 417 SUPERFAMILY SSF51011 307 400 1.08E-19 T 28-03-2018 CU254_RS25965 0126aad5c6bec5e1e56f2eb2f13b9239 417 Pfam PF17450 Alpha galactosidase A C-terminal beta sandwich domain 315 360 9.0E-5 T 28-03-2018 IPR035373 Alpha galactosidase A, C-terminal beta-sandwich domain CU254_RS25965 0126aad5c6bec5e1e56f2eb2f13b9239 417 SUPERFAMILY SSF51445 31 312 2.17E-91 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS25965 0126aad5c6bec5e1e56f2eb2f13b9239 417 Gene3D G3DSA:2.60.40.1180 310 413 4.9E-25 T 28-03-2018 CU254_RS20910 39fcb3938b3f7883cd45474cb56acfe9 175 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 39 108 9.4E-12 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CU254_RS20910 39fcb3938b3f7883cd45474cb56acfe9 175 Gene3D G3DSA:2.30.110.10 23 166 4.8E-21 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS20910 39fcb3938b3f7883cd45474cb56acfe9 175 SUPERFAMILY SSF50475 39 163 1.33E-21 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS23735 67ee9d90c6d439aafe8132e68d955f9f 118 Gene3D G3DSA:1.10.10.10 8 70 1.1E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS23735 67ee9d90c6d439aafe8132e68d955f9f 118 SUPERFAMILY SSF46785 5 116 2.33E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS23735 67ee9d90c6d439aafe8132e68d955f9f 118 Pfam PF03965 Penicillinase repressor 7 115 2.1E-27 T 28-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 CU254_RS25185 5dd86894328eac35cbaa54eaf3106cdb 461 Pfam PF08817 WXG100 protein secretion system (Wss), protein YukD 8 78 8.4E-11 T 28-03-2018 IPR024962 YukD-like CU254_RS25185 5dd86894328eac35cbaa54eaf3106cdb 461 TIGRFAM TIGR03920 T7SS_EccD: type VII secretion integral membrane protein EccD 11 455 1.8E-47 T 28-03-2018 IPR006707 Type VII secretion system membrane protein EccD CU254_RS19540 453061582f8f0b66ea3fbad6a4a7c059 132 SUPERFAMILY SSF55729 27 122 6.69E-17 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS19540 453061582f8f0b66ea3fbad6a4a7c059 132 Pfam PF00583 Acetyltransferase (GNAT) family 33 119 3.1E-10 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS19540 453061582f8f0b66ea3fbad6a4a7c059 132 Gene3D G3DSA:3.40.630.30 2 125 2.5E-17 T 28-03-2018 CU254_RS19700 8238c173dc18a888fd2f0818b862a82d 297 Pfam PF05853 beta-keto acid cleavage enzyme 5 291 8.6E-102 T 28-03-2018 IPR008567 3-keto-5-aminohexanoate cleavage enzyme GO:0016740|GO:0019475 KEGG: 00310+2.3.1.247|KEGG: 00600+2.3.1.24 CU254_RS19700 8238c173dc18a888fd2f0818b862a82d 297 Gene3D G3DSA:3.20.20.70 2 295 1.5E-108 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS12350 6fc367fd1194363132bfd3ff87b9707b 326 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 30 302 2.3E-67 T 28-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CU254_RS12350 6fc367fd1194363132bfd3ff87b9707b 326 SUPERFAMILY SSF50891 182 309 1.52E-13 T 28-03-2018 IPR029000 Cyclophilin-like domain CU254_RS12350 6fc367fd1194363132bfd3ff87b9707b 326 SMART SM00797 29 320 9.9E-89 T 28-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CU254_RS05975 093e02e085f3704501187421deb1dfb6 380 Gene3D G3DSA:3.30.420.40 1 187 2.4E-17 T 28-03-2018 CU254_RS05975 093e02e085f3704501187421deb1dfb6 380 SUPERFAMILY SSF53067 3 161 4.21E-19 T 28-03-2018 CU254_RS30120 a2d3d4b87ba7bcc64368691bebca862d 439 Pfam PF01844 HNH endonuclease 346 385 1.9E-5 T 28-03-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 CU254_RS30120 a2d3d4b87ba7bcc64368691bebca862d 439 SMART SM00507 329 381 4.6E-11 T 28-03-2018 IPR003615 HNH nuclease CU254_RS30120 a2d3d4b87ba7bcc64368691bebca862d 439 Pfam PF02720 Domain of unknown function (DUF222) 26 338 1.1E-44 T 28-03-2018 IPR003870 Domain of unknown function DUF222 CU254_RS30120 a2d3d4b87ba7bcc64368691bebca862d 439 Gene3D G3DSA:3.40.1800.10 320 391 6.2E-8 T 28-03-2018 CU254_RS39385 c46ee8ba061284add51913100425d7ef 165 Gene3D G3DSA:3.40.1000.10 23 165 2.6E-56 T 28-03-2018 CU254_RS39385 c46ee8ba061284add51913100425d7ef 165 Pfam PF09449 Domain of unknown function (DUF2020) 36 165 3.5E-41 T 28-03-2018 IPR018567 Domain of unknown function DUF2020 CU254_RS39385 c46ee8ba061284add51913100425d7ef 165 SUPERFAMILY SSF55724 22 165 6.28E-55 T 28-03-2018 IPR016123 Mog1/PsbP, alpha/beta/alpha sandwich Reactome: R-HSA-5576892 CU254_RS03015 c30b076337126df678b3d488754e19f9 325 PRINTS PR00069 Aldo-keto reductase signature 41 65 9.9E-5 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CU254_RS03015 c30b076337126df678b3d488754e19f9 325 PRINTS PR00069 Aldo-keto reductase signature 105 123 9.9E-5 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CU254_RS03015 c30b076337126df678b3d488754e19f9 325 PRINTS PR00069 Aldo-keto reductase signature 136 153 9.9E-5 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CU254_RS03015 c30b076337126df678b3d488754e19f9 325 Gene3D G3DSA:3.20.20.100 2 324 4.2E-106 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS03015 c30b076337126df678b3d488754e19f9 325 Pfam PF00248 Aldo/keto reductase family 17 304 4.7E-76 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS03015 c30b076337126df678b3d488754e19f9 325 SUPERFAMILY SSF51430 9 305 3.8E-97 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS24960 3a876f357e1490795e13a5e443ddd5c7 129 Gene3D G3DSA:3.30.1230.10 20 106 8.4E-26 T 28-03-2018 IPR007393 Domain of unknown function DUF448 CU254_RS24960 3a876f357e1490795e13a5e443ddd5c7 129 SUPERFAMILY SSF64376 26 97 4.71E-21 T 28-03-2018 IPR007393 Domain of unknown function DUF448 CU254_RS24960 3a876f357e1490795e13a5e443ddd5c7 129 Pfam PF04296 Protein of unknown function (DUF448) 31 93 9.1E-21 T 28-03-2018 IPR007393 Domain of unknown function DUF448 CU254_RS32205 d3c76d366193acdb4d07403ae960ff8b 253 Pfam PF01061 ABC-2 type transporter 11 216 4.0E-21 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CU254_RS32205 d3c76d366193acdb4d07403ae960ff8b 253 PIRSF PIRSF006648 2 253 6.7E-66 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CU254_RS07215 0067510db118533c5721521c4408fbda 432 Pfam PF13556 PucR C-terminal helix-turn-helix domain 336 394 1.0E-16 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CU254_RS07215 0067510db118533c5721521c4408fbda 432 Gene3D G3DSA:1.10.10.10 328 406 5.1E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS07215 0067510db118533c5721521c4408fbda 432 Gene3D G3DSA:1.10.10.10 117 208 0.17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS09090 f2414674b132c43cff077942aee82042 345 Gene3D G3DSA:1.10.287.1060 105 193 0.22 T 28-03-2018 CU254_RS09090 f2414674b132c43cff077942aee82042 345 SUPERFAMILY SSF140453 30 114 9.94E-5 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CU254_RS09090 f2414674b132c43cff077942aee82042 345 Gene3D G3DSA:1.10.287.850 24 104 4.8E-6 T 28-03-2018 CU254_RS19130 fb3aa5e4ad6e79c5333fc009b27b3c25 158 Pfam PF08592 Domain of unknown function (DUF1772) 21 150 8.1E-19 T 28-03-2018 IPR013901 Anthrone oxygenase CU254_RS41330 06637f7aee91f1c05a22b07f6a6dcce9 281 Gene3D G3DSA:3.40.50.150 2 281 1.3E-43 T 28-03-2018 CU254_RS41330 06637f7aee91f1c05a22b07f6a6dcce9 281 Pfam PF04672 S-adenosyl methyltransferase 12 280 2.0E-76 T 28-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CU254_RS41330 06637f7aee91f1c05a22b07f6a6dcce9 281 SUPERFAMILY SSF53335 17 243 8.0E-31 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS41330 06637f7aee91f1c05a22b07f6a6dcce9 281 PIRSF PIRSF017393 1 281 1.3E-83 T 28-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CU254_RS29920 c506cfa556547ccc577eaf77a5b64d3f 288 Pfam PF12697 Alpha/beta hydrolase family 31 276 5.9E-13 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS29920 c506cfa556547ccc577eaf77a5b64d3f 288 SUPERFAMILY SSF53474 11 283 1.28E-47 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS29920 c506cfa556547ccc577eaf77a5b64d3f 288 Gene3D G3DSA:3.40.50.1820 8 286 1.4E-35 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS29920 c506cfa556547ccc577eaf77a5b64d3f 288 PRINTS PR00111 Alpha/beta hydrolase fold signature 101 114 2.6E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS29920 c506cfa556547ccc577eaf77a5b64d3f 288 PRINTS PR00111 Alpha/beta hydrolase fold signature 229 243 2.6E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS29920 c506cfa556547ccc577eaf77a5b64d3f 288 PRINTS PR00111 Alpha/beta hydrolase fold signature 115 128 2.6E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS01375 552000ec50a91fbfb4dd9668b55fce7d 448 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 26 358 24.494 T 28-03-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS01375 552000ec50a91fbfb4dd9668b55fce7d 448 Pfam PF00146 NADH dehydrogenase 33 351 8.0E-126 T 28-03-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS01375 552000ec50a91fbfb4dd9668b55fce7d 448 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 236 249 - T 28-03-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS28520 160bcd0923b6c9a9400d4ef2aa7f0c58 242 TIGRFAM TIGR00715 precor6x_red: precorrin-6x reductase 1 241 7.6E-49 T 28-03-2018 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 CU254_RS28520 160bcd0923b6c9a9400d4ef2aa7f0c58 242 Gene3D G3DSA:3.40.50.2300 2 66 0.03 T 28-03-2018 CU254_RS28520 160bcd0923b6c9a9400d4ef2aa7f0c58 242 Pfam PF02571 Precorrin-6x reductase CbiJ/CobK 3 239 6.0E-74 T 28-03-2018 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 CU254_RS28520 160bcd0923b6c9a9400d4ef2aa7f0c58 242 Gene3D G3DSA:3.40.50.2300 67 239 1.4E-17 T 28-03-2018 CU254_RS03520 50236e78ffea9643cb141977494e7b3c 361 Pfam PF13439 Glycosyltransferase Family 4 16 172 4.3E-12 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CU254_RS03520 50236e78ffea9643cb141977494e7b3c 361 Pfam PF00534 Glycosyl transferases group 1 183 340 4.3E-26 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CU254_RS03520 50236e78ffea9643cb141977494e7b3c 361 Gene3D G3DSA:3.40.50.2000 170 346 1.0E-38 T 28-03-2018 CU254_RS03520 50236e78ffea9643cb141977494e7b3c 361 SUPERFAMILY SSF53756 6 359 1.1E-64 T 28-03-2018 CU254_RS08425 d39c67aa75fb88ecd92012cff7d0044e 318 Gene3D G3DSA:3.30.200.20 90 204 3.1E-18 T 28-03-2018 CU254_RS08425 d39c67aa75fb88ecd92012cff7d0044e 318 Pfam PF01163 RIO1 family 135 298 2.2E-32 T 28-03-2018 CU254_RS08425 d39c67aa75fb88ecd92012cff7d0044e 318 SUPERFAMILY SSF56112 94 292 1.13E-17 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS08425 d39c67aa75fb88ecd92012cff7d0044e 318 SMART SM00090 61 313 2.2E-9 T 28-03-2018 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|Reactome: R-HSA-6791226 CU254_RS08425 d39c67aa75fb88ecd92012cff7d0044e 318 Gene3D G3DSA:1.10.510.10 207 314 9.4E-8 T 28-03-2018 CU254_RS29355 ccc1570bdd959367cec2b5ebdc5c8dd9 183 SUPERFAMILY SSF52499 2 178 2.88E-40 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CU254_RS29355 ccc1570bdd959367cec2b5ebdc5c8dd9 183 Pfam PF00857 Isochorismatase family 3 169 4.7E-31 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CU254_RS29355 ccc1570bdd959367cec2b5ebdc5c8dd9 183 Gene3D G3DSA:3.40.50.850 1 181 8.9E-37 T 28-03-2018 CU254_RS11400 41b5a6556df4f158b7d04c3f7070e8ff 138 SUPERFAMILY SSF50475 2 135 8.04E-24 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS11400 41b5a6556df4f158b7d04c3f7070e8ff 138 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 4 91 2.2E-12 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CU254_RS11400 41b5a6556df4f158b7d04c3f7070e8ff 138 Gene3D G3DSA:2.30.110.10 1 136 1.3E-21 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS06535 cc44f39e77ef37b860a3d37d291b609b 143 Pfam PF12802 MarR family 32 89 9.3E-10 T 28-03-2018 CU254_RS06535 cc44f39e77ef37b860a3d37d291b609b 143 Gene3D G3DSA:1.10.10.10 1 143 4.1E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS06535 cc44f39e77ef37b860a3d37d291b609b 143 SUPERFAMILY SSF46785 7 141 5.77E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS06535 cc44f39e77ef37b860a3d37d291b609b 143 SMART SM00347 26 126 6.2E-16 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS22960 e083be218bfbc9f8aee0fc8a1c289472 382 Gene3D G3DSA:1.20.1250.20 190 380 6.3E-12 T 28-03-2018 CU254_RS22960 e083be218bfbc9f8aee0fc8a1c289472 382 SUPERFAMILY SSF103473 8 372 2.49E-26 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS22960 e083be218bfbc9f8aee0fc8a1c289472 382 Gene3D G3DSA:1.20.1250.20 1 187 4.4E-13 T 28-03-2018 CU254_RS11455 f98b26d047112bc7fd7c9854786f578e 152 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 15 146 21.317 T 28-03-2018 IPR011605 NusB antitermination factor GO:0006353 CU254_RS11455 f98b26d047112bc7fd7c9854786f578e 152 SUPERFAMILY SSF48013 16 141 3.27E-38 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CU254_RS11455 f98b26d047112bc7fd7c9854786f578e 152 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 16 141 2.8E-39 T 28-03-2018 IPR011605 NusB antitermination factor GO:0006353 CU254_RS11455 f98b26d047112bc7fd7c9854786f578e 152 Pfam PF01029 NusB family 18 141 2.2E-34 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CU254_RS11455 f98b26d047112bc7fd7c9854786f578e 152 Gene3D G3DSA:1.10.940.10 13 147 2.6E-41 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CU254_RS09665 ab38e9a39c913bf9cd2cf9d0ec9d15b2 215 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 15 106 2.8E-18 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CU254_RS09665 ab38e9a39c913bf9cd2cf9d0ec9d15b2 215 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 30 210 2.6E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS09665 ab38e9a39c913bf9cd2cf9d0ec9d15b2 215 SUPERFAMILY SSF161098 11 197 1.83E-35 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS09665 ab38e9a39c913bf9cd2cf9d0ec9d15b2 215 Gene3D G3DSA:1.10.3720.10 3 214 1.4E-33 T 28-03-2018 CU254_RS39200 d597d490f9b237e65547cc66e9309b75 307 Pfam PF13614 AAA domain 45 223 3.7E-59 T 28-03-2018 IPR025669 AAA domain CU254_RS39200 d597d490f9b237e65547cc66e9309b75 307 Gene3D G3DSA:3.40.50.300 44 306 5.9E-60 T 28-03-2018 CU254_RS39200 d597d490f9b237e65547cc66e9309b75 307 SUPERFAMILY SSF52540 45 300 5.81E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS39110 13e7766179fc43abbe7fa0d27a058752 742 Pfam PF15567 Immunity protein 35 4 100 1.1E-23 T 28-03-2018 IPR029082 Immunity protein 35 CU254_RS39110 13e7766179fc43abbe7fa0d27a058752 742 Pfam PF03747 ADP-ribosylglycohydrolase 392 699 4.0E-27 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 CU254_RS39110 13e7766179fc43abbe7fa0d27a058752 742 SUPERFAMILY SSF101478 388 717 5.62E-22 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 CU254_RS39110 13e7766179fc43abbe7fa0d27a058752 742 Gene3D G3DSA:1.10.4080.10 387 732 6.5E-35 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 CU254_RS31740 f6b2999363d8375fcfa587686834e698 356 SUPERFAMILY SSF159245 28 348 9.81E-5 T 28-03-2018 CU254_RS29025 909879e6a6b69f48dd2577dfe83c7c52 138 SUPERFAMILY SSF54909 1 98 4.56E-15 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS29025 909879e6a6b69f48dd2577dfe83c7c52 138 SMART SM00886 2 93 1.5E-10 T 28-03-2018 IPR013097 Stress responsive alpha-beta barrel CU254_RS29025 909879e6a6b69f48dd2577dfe83c7c52 138 Pfam PF07876 Stress responsive A/B Barrel Domain 2 91 1.3E-12 T 28-03-2018 IPR013097 Stress responsive alpha-beta barrel CU254_RS29025 909879e6a6b69f48dd2577dfe83c7c52 138 Gene3D G3DSA:3.30.70.100 1 96 2.0E-13 T 28-03-2018 CU254_RS31735 cc640da737a6014c363567b79834c98b 226 SUPERFAMILY SSF46689 37 111 4.51E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS31735 cc640da737a6014c363567b79834c98b 226 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 48 61 4.5E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS31735 cc640da737a6014c363567b79834c98b 226 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 69 92 4.5E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS31735 cc640da737a6014c363567b79834c98b 226 Pfam PF00440 Bacterial regulatory proteins, tetR family 48 94 1.9E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS31735 cc640da737a6014c363567b79834c98b 226 ProSitePatterns PS01081 TetR-type HTH domain signature. 60 90 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CU254_RS31735 cc640da737a6014c363567b79834c98b 226 Gene3D G3DSA:1.10.357.10 92 225 5.9E-13 T 28-03-2018 CU254_RS31735 cc640da737a6014c363567b79834c98b 226 Gene3D G3DSA:1.10.10.60 7 91 2.6E-17 T 28-03-2018 CU254_RS05085 670dc474a67be2cf8c174f21ad95b60f 327 Pfam PF02653 Branched-chain amino acid transport system / permease component 51 315 5.0E-44 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CU254_RS05085 670dc474a67be2cf8c174f21ad95b60f 327 Gene3D G3DSA:1.10.3470.10 45 320 3.5E-31 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CU254_RS41475 210d6d661bc8345d733d45d8bd186c4e 182 SUPERFAMILY SSF51182 21 159 3.49E-14 T 28-03-2018 IPR011051 RmlC-like cupin domain CU254_RS41475 210d6d661bc8345d733d45d8bd186c4e 182 Pfam PF07883 Cupin domain 60 119 1.9E-7 T 28-03-2018 IPR013096 Cupin 2, conserved barrel CU254_RS41475 210d6d661bc8345d733d45d8bd186c4e 182 Gene3D G3DSA:2.60.120.10 15 160 1.1E-12 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS31310 4244f53d2ad0764a054b8299f828df86 93 Pfam PF12815 Spt5 C-terminal nonapeptide repeat binding Spt4 29 82 9.7E-7 T 28-03-2018 CU254_RS18585 89201529d26b01b3daf519c9c181b9f8 227 SUPERFAMILY SSF53639 5 209 2.16E-48 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CU254_RS18585 89201529d26b01b3daf519c9c181b9f8 227 SMART SM01007 6 185 1.6E-40 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CU254_RS18585 89201529d26b01b3daf519c9c181b9f8 227 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 8 185 4.1E-40 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CU254_RS18585 89201529d26b01b3daf519c9c181b9f8 227 Gene3D G3DSA:3.40.225.10 2 227 3.4E-56 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CU254_RS28955 de5374ff1fc32fb3086b3fd5e4027c19 243 Pfam PF07335 Fungal chitosanase of glycosyl hydrolase group 75 80 240 2.3E-13 T 28-03-2018 IPR009939 Fungal chitosanase KEGG: 00520+3.2.1.132 CU254_RS29835 4ca0717b8f6427798ccef3f95abc187e 366 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 253 259 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CU254_RS29835 4ca0717b8f6427798ccef3f95abc187e 366 SUPERFAMILY SSF53335 154 302 2.79E-34 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS29835 4ca0717b8f6427798ccef3f95abc187e 366 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 187 256 2.7E-13 T 28-03-2018 CU254_RS29835 4ca0717b8f6427798ccef3f95abc187e 366 Gene3D G3DSA:3.40.50.150 43 364 4.0E-30 T 28-03-2018 CU254_RS41235 bc00b296b24b07a866641a57e48e733b 590 SMART SM00530 202 258 5.3E-15 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS41235 bc00b296b24b07a866641a57e48e733b 590 SUPERFAMILY SSF47413 198 263 1.23E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS41235 bc00b296b24b07a866641a57e48e733b 590 Gene3D G3DSA:1.10.260.40 194 265 8.1E-19 T 28-03-2018 CU254_RS41235 bc00b296b24b07a866641a57e48e733b 590 Pfam PF13560 Helix-turn-helix domain 198 258 4.8E-14 T 28-03-2018 CU254_RS14590 7e5473f2436a7e1120a3f8a7f8f4cb70 270 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 107 127 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CU254_RS14590 7e5473f2436a7e1120a3f8a7f8f4cb70 270 Pfam PF00378 Enoyl-CoA hydratase/isomerase 17 265 4.9E-42 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CU254_RS14590 7e5473f2436a7e1120a3f8a7f8f4cb70 270 SUPERFAMILY SSF52096 17 264 5.14E-62 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS14590 7e5473f2436a7e1120a3f8a7f8f4cb70 270 Gene3D G3DSA:1.10.12.10 225 269 2.9E-8 T 28-03-2018 IPR014748 Crontonase, C-terminal CU254_RS14590 7e5473f2436a7e1120a3f8a7f8f4cb70 270 Gene3D G3DSA:3.90.226.10 2 224 7.2E-46 T 28-03-2018 CU254_RS17730 3666473e555ebc31b06316e0e5de2cbf 295 Gene3D G3DSA:1.10.10.10 1 87 5.4E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS17730 3666473e555ebc31b06316e0e5de2cbf 295 Pfam PF03466 LysR substrate binding domain 86 289 1.3E-26 T 28-03-2018 IPR005119 LysR, substrate-binding CU254_RS17730 3666473e555ebc31b06316e0e5de2cbf 295 Gene3D G3DSA:3.40.190.10 182 269 1.9E-14 T 28-03-2018 CU254_RS17730 3666473e555ebc31b06316e0e5de2cbf 295 SUPERFAMILY SSF46785 1 82 1.52E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS17730 3666473e555ebc31b06316e0e5de2cbf 295 Gene3D G3DSA:3.40.190.10 88 181 6.6E-16 T 28-03-2018 CU254_RS17730 3666473e555ebc31b06316e0e5de2cbf 295 SUPERFAMILY SSF53850 87 292 2.25E-24 T 28-03-2018 CU254_RS17730 3666473e555ebc31b06316e0e5de2cbf 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 8.3E-13 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CU254_RS22340 e3d99856dca561fd74b6804ae06fa23c 236 Gene3D G3DSA:3.40.50.1860 109 199 1.3E-12 T 28-03-2018 CU254_RS22340 e3d99856dca561fd74b6804ae06fa23c 236 Gene3D G3DSA:3.40.50.1860 1 108 0.088 T 28-03-2018 CU254_RS27805 217d09a37baeeec2f87bccaf4ae092bc 135 SMART SM00347 28 128 4.6E-15 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS27805 217d09a37baeeec2f87bccaf4ae092bc 135 Pfam PF12802 MarR family 34 92 3.0E-9 T 28-03-2018 CU254_RS27805 217d09a37baeeec2f87bccaf4ae092bc 135 SUPERFAMILY SSF46785 10 119 1.7E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS27805 217d09a37baeeec2f87bccaf4ae092bc 135 Gene3D G3DSA:1.10.10.10 4 123 1.1E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS15450 d71f23e569ebc21facd5094626ad15c6 603 Pfam PF00723 Glycosyl hydrolases family 15 216 579 7.1E-59 T 28-03-2018 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: R-HSA-70221 CU254_RS15450 d71f23e569ebc21facd5094626ad15c6 603 Gene3D G3DSA:1.25.40.10 529 576 0.0015 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS15450 d71f23e569ebc21facd5094626ad15c6 603 SUPERFAMILY SSF48208 187 586 2.62E-104 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CU254_RS15450 d71f23e569ebc21facd5094626ad15c6 603 Gene3D G3DSA:1.50.10.10 182 528 7.4E-98 T 28-03-2018 CU254_RS21440 76461a9901b2198a59ff80779bb2057d 149 Gene3D G3DSA:2.60.120.10 2 130 4.5E-18 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS21440 76461a9901b2198a59ff80779bb2057d 149 Pfam PF07883 Cupin domain 45 94 1.1E-10 T 28-03-2018 IPR013096 Cupin 2, conserved barrel CU254_RS21440 76461a9901b2198a59ff80779bb2057d 149 SUPERFAMILY SSF51182 18 140 2.15E-16 T 28-03-2018 IPR011051 RmlC-like cupin domain CU254_RS06675 2cca846f414ae7dacbaf259730795b98 132 SUPERFAMILY SSF46785 4 119 1.37E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS06675 2cca846f414ae7dacbaf259730795b98 132 PRINTS PR00598 Bacterial regulatory protein MarR family signature 81 97 1.8E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS06675 2cca846f414ae7dacbaf259730795b98 132 PRINTS PR00598 Bacterial regulatory protein MarR family signature 62 77 1.8E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS06675 2cca846f414ae7dacbaf259730795b98 132 PRINTS PR00598 Bacterial regulatory protein MarR family signature 45 61 1.8E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS06675 2cca846f414ae7dacbaf259730795b98 132 SMART SM00347 19 121 3.0E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS06675 2cca846f414ae7dacbaf259730795b98 132 Pfam PF12802 MarR family 29 85 1.3E-10 T 28-03-2018 CU254_RS06675 2cca846f414ae7dacbaf259730795b98 132 Gene3D G3DSA:1.10.10.10 1 130 2.4E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS27180 85dd715ad0b09d41f42272ca1debcce0 382 Pfam PF01261 Xylose isomerase-like TIM barrel 43 263 2.5E-26 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CU254_RS27180 85dd715ad0b09d41f42272ca1debcce0 382 TIGRFAM TIGR02631 xylA_Arthro: xylose isomerase 4 379 1.3E-197 T 28-03-2018 IPR013453 Xylose isomerase, actinobacteria GO:0009045|GO:0042732 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CU254_RS27180 85dd715ad0b09d41f42272ca1debcce0 382 Gene3D G3DSA:3.20.20.150 6 381 3.1E-84 T 28-03-2018 CU254_RS27180 85dd715ad0b09d41f42272ca1debcce0 382 SUPERFAMILY SSF51658 8 381 1.01E-112 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CU254_RS27180 85dd715ad0b09d41f42272ca1debcce0 382 PRINTS PR00688 Xylose isomerase signature 127 148 1.8E-52 T 28-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CU254_RS27180 85dd715ad0b09d41f42272ca1debcce0 382 PRINTS PR00688 Xylose isomerase signature 46 68 1.8E-52 T 28-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CU254_RS27180 85dd715ad0b09d41f42272ca1debcce0 382 PRINTS PR00688 Xylose isomerase signature 176 200 1.8E-52 T 28-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CU254_RS27180 85dd715ad0b09d41f42272ca1debcce0 382 PRINTS PR00688 Xylose isomerase signature 279 290 1.8E-52 T 28-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CU254_RS27180 85dd715ad0b09d41f42272ca1debcce0 382 PRINTS PR00688 Xylose isomerase signature 246 257 1.8E-52 T 28-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CU254_RS27180 85dd715ad0b09d41f42272ca1debcce0 382 PRINTS PR00688 Xylose isomerase signature 103 122 1.8E-52 T 28-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CU254_RS27180 85dd715ad0b09d41f42272ca1debcce0 382 PRINTS PR00688 Xylose isomerase signature 218 245 1.8E-52 T 28-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CU254_RS27180 85dd715ad0b09d41f42272ca1debcce0 382 PRINTS PR00688 Xylose isomerase signature 154 173 1.8E-52 T 28-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CU254_RS27180 85dd715ad0b09d41f42272ca1debcce0 382 Hamap MF_00455 Xylose isomerase [xylA]. 2 378 34.27 T 28-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CU254_RS24150 716c2a9b65d1a2e2919d8041e6986cbc 205 Pfam PF00005 ABC transporter 20 160 2.5E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS24150 716c2a9b65d1a2e2919d8041e6986cbc 205 SUPERFAMILY SSF52540 4 201 6.56E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS24150 716c2a9b65d1a2e2919d8041e6986cbc 205 Gene3D G3DSA:3.40.50.300 1 205 1.1E-47 T 28-03-2018 CU254_RS24150 716c2a9b65d1a2e2919d8041e6986cbc 205 SMART SM00382 29 205 2.1E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS04085 1ecaeb64eab088a3ae961bd4f4b6fdee 109 SUPERFAMILY SSF46767 3 78 1.7E-14 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CU254_RS04085 1ecaeb64eab088a3ae961bd4f4b6fdee 109 Gene3D G3DSA:1.10.10.10 1 103 5.9E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS04085 1ecaeb64eab088a3ae961bd4f4b6fdee 109 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 6 79 2.2E-15 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CU254_RS36910 57c36729c187c061b715d01a3b71e35b 396 SUPERFAMILY SSF103365 9 396 6.41E-130 T 28-03-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 CU254_RS36910 57c36729c187c061b715d01a3b71e35b 396 Pfam PF01139 tRNA-splicing ligase RtcB 28 396 7.3E-131 T 28-03-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 CU254_RS22750 d0160c95740f0b675a966669ff5dd2df 312 Gene3D G3DSA:1.20.1070.10 41 297 4.2E-4 T 28-03-2018 CU254_RS22750 d0160c95740f0b675a966669ff5dd2df 312 Pfam PF12679 ABC-2 family transporter protein 51 310 2.7E-15 T 28-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 CU254_RS10710 f47d9d05b63d7c8029b2f50ba8af0f49 304 Gene3D G3DSA:3.40.1790.10 1 304 4.1E-125 T 28-03-2018 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 CU254_RS10710 f47d9d05b63d7c8029b2f50ba8af0f49 304 Hamap MF_01876 Pseudouridine-5'-phosphate glycosidase [psuG]. 12 304 37.375 T 28-03-2018 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 CU254_RS10710 f47d9d05b63d7c8029b2f50ba8af0f49 304 SUPERFAMILY SSF110581 7 303 1.7E-95 T 28-03-2018 CU254_RS10710 f47d9d05b63d7c8029b2f50ba8af0f49 304 Pfam PF04227 Indigoidine synthase A like protein 13 302 1.6E-112 T 28-03-2018 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 CU254_RS22070 3c1a75ee312825d012342bd85a838d6e 508 Gene3D G3DSA:3.20.20.140 183 386 2.3E-25 T 28-03-2018 CU254_RS22070 3c1a75ee312825d012342bd85a838d6e 508 SUPERFAMILY SSF89550 191 393 4.58E-33 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CU254_RS22070 3c1a75ee312825d012342bd85a838d6e 508 SMART SM00481 194 258 0.0038 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CU254_RS42105 8bf02a46de6de4790a8739887f8ab84e 439 Gene3D G3DSA:1.20.1250.20 229 439 3.6E-35 T 28-03-2018 CU254_RS42105 8bf02a46de6de4790a8739887f8ab84e 439 SUPERFAMILY SSF103473 3 436 8.5E-85 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS42105 8bf02a46de6de4790a8739887f8ab84e 439 ProSitePatterns PS00216 Sugar transport proteins signature 1. 64 80 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CU254_RS42105 8bf02a46de6de4790a8739887f8ab84e 439 Pfam PF00083 Sugar (and other) transporter 47 438 4.8E-39 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CU254_RS42105 8bf02a46de6de4790a8739887f8ab84e 439 Gene3D G3DSA:1.20.1250.20 3 205 9.0E-34 T 28-03-2018 CU254_RS42105 8bf02a46de6de4790a8739887f8ab84e 439 ProSitePatterns PS00217 Sugar transport proteins signature 2. 106 131 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CU254_RS32595 ff80c70b52605acb30558dfc5deff346 1101 Gene3D G3DSA:3.90.550.10 2 257 9.3E-34 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS32595 ff80c70b52605acb30558dfc5deff346 1101 Pfam PF00535 Glycosyl transferase family 2 18 142 1.5E-15 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CU254_RS32595 ff80c70b52605acb30558dfc5deff346 1101 SUPERFAMILY SSF53448 15 238 6.61E-33 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS39850 1af782df9fd2db5839cb913ef4439384 521 Pfam PF01757 Acyltransferase family 26 348 3.4E-28 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CU254_RS38165 7bd15c3648c99bd45b47250eb4a5b30f 329 Gene3D G3DSA:1.10.3470.10 11 326 1.0E-19 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CU254_RS38165 7bd15c3648c99bd45b47250eb4a5b30f 329 Pfam PF02653 Branched-chain amino acid transport system / permease component 50 317 2.7E-38 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CU254_RS05270 77c045e391225ca124163f00c06d5768 295 SUPERFAMILY SSF47413 35 83 4.97E-6 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS05270 77c045e391225ca124163f00c06d5768 295 Gene3D G3DSA:1.10.260.40 2 105 1.2E-11 T 28-03-2018 CU254_RS05270 77c045e391225ca124163f00c06d5768 295 Pfam PF13560 Helix-turn-helix domain 17 89 1.6E-11 T 28-03-2018 CU254_RS05270 77c045e391225ca124163f00c06d5768 295 SMART SM00530 9 86 1.5E-4 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS23400 2ec252b16d7a0e89e0d0d4802209e50e 186 SUPERFAMILY SSF46689 3 67 2.41E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS23400 2ec252b16d7a0e89e0d0d4802209e50e 186 Gene3D G3DSA:1.10.357.10 48 175 4.7E-16 T 28-03-2018 CU254_RS23400 2ec252b16d7a0e89e0d0d4802209e50e 186 Pfam PF00440 Bacterial regulatory proteins, tetR family 6 46 2.6E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS23400 2ec252b16d7a0e89e0d0d4802209e50e 186 Gene3D G3DSA:1.10.10.60 2 47 8.7E-11 T 28-03-2018 CU254_RS02795 e622dca0e37af0a6ab2a53df87276764 326 Gene3D G3DSA:3.40.960.10 199 315 2.9E-5 T 28-03-2018 CU254_RS09985 f73e5b0589532d995318c45d596a2af3 292 Pfam PF05368 NmrA-like family 4 222 2.2E-24 T 28-03-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 CU254_RS09985 f73e5b0589532d995318c45d596a2af3 292 Gene3D G3DSA:3.40.50.720 1 143 7.1E-20 T 28-03-2018 CU254_RS09985 f73e5b0589532d995318c45d596a2af3 292 Gene3D G3DSA:3.90.25.10 144 292 3.9E-13 T 28-03-2018 CU254_RS09985 f73e5b0589532d995318c45d596a2af3 292 SUPERFAMILY SSF51735 1 237 6.76E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS10900 28761f250264ea7813b0a337da1f00fc 248 PIRSF PIRSF010219 7 227 3.4E-72 T 28-03-2018 IPR016566 Uncharacterised conserved protein UCP010219 CU254_RS10900 28761f250264ea7813b0a337da1f00fc 248 Pfam PF11361 Protein of unknown function (DUF3159) 30 214 3.4E-66 T 28-03-2018 IPR016566 Uncharacterised conserved protein UCP010219 CU254_RS38650 a63c41db73b97b6ad9dcc7b9ebe6e27f 168 Pfam PF07681 DoxX 6 100 2.2E-12 T 28-03-2018 IPR032808 DoxX family CU254_RS37280 1c9dd76bcaca0a7aa80053c4c87cd304 308 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 44 297 4.4E-61 T 28-03-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 CU254_RS37280 1c9dd76bcaca0a7aa80053c4c87cd304 308 SUPERFAMILY SSF51197 42 308 5.49E-88 T 28-03-2018 CU254_RS37280 1c9dd76bcaca0a7aa80053c4c87cd304 308 Gene3D G3DSA:3.60.130.10 38 308 1.1E-69 T 28-03-2018 CU254_RS11545 7303d1ec8c3f4fa519044343d98ba6ad 206 SUPERFAMILY SSF55073 11 136 4.08E-5 T 28-03-2018 IPR029787 Nucleotide cyclase CU254_RS19280 495b8d85a21eb461516e3bf54556a203 316 SUPERFAMILY SSF54919 48 189 2.78E-5 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CU254_RS19280 495b8d85a21eb461516e3bf54556a203 316 Pfam PF00334 Nucleoside diphosphate kinase 48 187 4.2E-5 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CU254_RS19280 495b8d85a21eb461516e3bf54556a203 316 Gene3D G3DSA:3.30.70.141 44 204 1.3E-11 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CU254_RS38345 5875214f28d7e1484e1067b1f8f1251a 186 SUPERFAMILY SSF46689 7 84 2.31E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS38345 5875214f28d7e1484e1067b1f8f1251a 186 Gene3D G3DSA:1.10.357.10 7 186 1.9E-28 T 28-03-2018 CU254_RS38345 5875214f28d7e1484e1067b1f8f1251a 186 SUPERFAMILY SSF48498 92 184 2.28E-7 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS38345 5875214f28d7e1484e1067b1f8f1251a 186 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 64 3.3E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS34745 3b1a4e44513568ffd2b023e6f4480055 407 Pfam PF13529 Peptidase_C39 like family 211 362 2.1E-29 T 28-03-2018 CU254_RS34745 3b1a4e44513568ffd2b023e6f4480055 407 Gene3D G3DSA:3.90.70.10 232 407 8.2E-21 T 28-03-2018 CU254_RS39015 2d89a5036e47e876d1fb4384a5932e1b 406 Pfam PF01594 AI-2E family transporter 37 359 3.8E-63 T 28-03-2018 IPR002549 Transmembrane protein TqsA-like CU254_RS37515 99626de2a84e6b72c324e035720efbde 281 Gene3D G3DSA:3.20.10.10 118 276 4.1E-38 T 28-03-2018 CU254_RS37515 99626de2a84e6b72c324e035720efbde 281 Gene3D G3DSA:3.30.470.10 3 113 5.9E-24 T 28-03-2018 CU254_RS37515 99626de2a84e6b72c324e035720efbde 281 SUPERFAMILY SSF56752 4 266 3.27E-53 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CU254_RS37515 99626de2a84e6b72c324e035720efbde 281 Pfam PF01063 Amino-transferase class IV 31 256 1.9E-39 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CU254_RS06755 52a15039968c414b9dbb4cf8a309cf58 379 Pfam PF02720 Domain of unknown function (DUF222) 3 289 5.5E-18 T 28-03-2018 IPR003870 Domain of unknown function DUF222 CU254_RS21325 4e0a56f6843840c47164603aa8499ba5 89 Pfam PF11239 Protein of unknown function (DUF3040) 1 78 3.0E-16 T 28-03-2018 IPR021401 Protein of unknown function DUF3040 CU254_RS38105 3ea08fd85da487b3a0c87db7e242e012 190 Gene3D G3DSA:1.10.260.40 40 173 3.7E-8 T 28-03-2018 CU254_RS38105 3ea08fd85da487b3a0c87db7e242e012 190 SUPERFAMILY SSF46689 5 73 4.67E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS38105 3ea08fd85da487b3a0c87db7e242e012 190 Gene3D G3DSA:1.10.10.60 5 39 9.1E-13 T 28-03-2018 CU254_RS38105 3ea08fd85da487b3a0c87db7e242e012 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 53 2.1E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS38105 3ea08fd85da487b3a0c87db7e242e012 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 3.8E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS38105 3ea08fd85da487b3a0c87db7e242e012 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 54 3.8E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS00180 097c49a76d5bc2d88c04c29f354d995a 121 Pfam PF04248 Domain of unknown function (DUF427) 23 113 1.4E-31 T 28-03-2018 IPR007361 Domain of unknown function DUF427 CU254_RS21545 2c2c5bf53cfa8c40990e5787a026ca1b 348 SUPERFAMILY SSF46689 299 347 1.37E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS21545 2c2c5bf53cfa8c40990e5787a026ca1b 348 Pfam PF02954 Bacterial regulatory protein, Fis family 305 345 7.6E-15 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CU254_RS21545 2c2c5bf53cfa8c40990e5787a026ca1b 348 Gene3D G3DSA:1.10.10.60 252 348 8.0E-16 T 28-03-2018 CU254_RS21545 2c2c5bf53cfa8c40990e5787a026ca1b 348 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 311 328 1.7E-10 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CU254_RS21545 2c2c5bf53cfa8c40990e5787a026ca1b 348 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 328 348 1.7E-10 T 28-03-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 CU254_RS17930 792746ed64fea152588392dfa844a9ed 420 SUPERFAMILY SSF55931 36 265 1.37E-33 T 28-03-2018 CU254_RS17930 792746ed64fea152588392dfa844a9ed 420 SUPERFAMILY SSF55931 305 383 1.37E-33 T 28-03-2018 CU254_RS17930 792746ed64fea152588392dfa844a9ed 420 Hamap MF_02034 Glutamate--cysteine ligase EgtA [egtA]. 20 417 29.326 T 28-03-2018 IPR017809 Glutamate--cysteine ligase EgtA, Actinobacteria GO:0004357|GO:0052699 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CU254_RS17930 792746ed64fea152588392dfa844a9ed 420 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 88 350 5.8E-45 T 28-03-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CU254_RS17930 792746ed64fea152588392dfa844a9ed 420 PIRSF PIRSF017901 2 418 5.9E-90 T 28-03-2018 IPR035434 Glutamate--cysteine ligase, bacteria and plant GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CU254_RS17550 0770d266932ebce6d14dec82feb022de 248 Pfam PF01925 Sulfite exporter TauE/SafE 14 239 5.1E-22 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CU254_RS35755 3a3976d475b55dbc5afc60936bd9d3ce 235 SUPERFAMILY SSF52317 20 210 6.81E-25 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS35755 3a3976d475b55dbc5afc60936bd9d3ce 235 Gene3D G3DSA:3.40.50.880 11 230 1.2E-19 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS35755 3a3976d475b55dbc5afc60936bd9d3ce 235 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 8 197 6.4E-36 T 28-03-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 CU254_RS33275 9914317fd73914455003438a62ff9a04 339 Gene3D G3DSA:3.40.50.720 7 189 0.0087 T 28-03-2018 CU254_RS33275 9914317fd73914455003438a62ff9a04 339 Pfam PF13692 Glycosyl transferases group 1 234 332 1.1E-6 T 28-03-2018 CU254_RS33275 9914317fd73914455003438a62ff9a04 339 Pfam PF06925 Monogalactosyldiacylglycerol (MGDG) synthase 15 167 3.3E-8 T 28-03-2018 IPR009695 Diacylglycerol glucosyltransferase, N-terminal GO:0009247|GO:0016758 CU254_RS33275 9914317fd73914455003438a62ff9a04 339 Gene3D G3DSA:3.40.50.2000 190 338 1.4E-21 T 28-03-2018 CU254_RS33275 9914317fd73914455003438a62ff9a04 339 SUPERFAMILY SSF53756 89 334 1.19E-21 T 28-03-2018 CU254_RS14965 fd78de725c0d28ea82a6d08a8f2d8ec0 346 Pfam PF13416 Bacterial extracellular solute-binding protein 48 301 1.9E-25 T 28-03-2018 CU254_RS14965 fd78de725c0d28ea82a6d08a8f2d8ec0 346 Gene3D G3DSA:3.40.190.10 142 299 4.8E-21 T 28-03-2018 CU254_RS14965 fd78de725c0d28ea82a6d08a8f2d8ec0 346 Gene3D G3DSA:3.40.190.10 21 141 2.7E-9 T 28-03-2018 CU254_RS14965 fd78de725c0d28ea82a6d08a8f2d8ec0 346 SUPERFAMILY SSF53850 30 346 1.26E-43 T 28-03-2018 CU254_RS33890 30dd5f575ecb4bce9bf864da065fd2ad 379 Gene3D G3DSA:2.120.10.30 3 110 0.091 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CU254_RS33890 30dd5f575ecb4bce9bf864da065fd2ad 379 Gene3D G3DSA:2.130.10.10 111 364 9.8E-14 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CU254_RS33890 30dd5f575ecb4bce9bf864da065fd2ad 379 SUPERFAMILY SSF50969 68 300 3.37E-12 T 28-03-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like CU254_RS00900 5478ebfd631e5c950d675f540b5cb4bb 97 Pfam PF10724 Protein of unknown function (DUF2516) 3 93 3.0E-29 T 28-03-2018 IPR019662 Protein of unknown function DUF2516 CU254_RS03895 cede5d6ea2bab037aeeb2dfd9c37cf58 370 Gene3D G3DSA:3.40.50.150 97 329 0.0011 T 28-03-2018 CU254_RS03895 cede5d6ea2bab037aeeb2dfd9c37cf58 370 Pfam PF10094 Uncharacterized protein conserved in bacteria (DUF2332) 8 368 4.4E-112 T 28-03-2018 IPR011200 Uncharacterised conserved protein UCP012608 CU254_RS10890 0e55418defac1afbe345bceb335dd678 237 Gene3D G3DSA:3.40.50.1820 4 217 2.4E-14 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS10890 0e55418defac1afbe345bceb335dd678 237 SUPERFAMILY SSF53474 8 207 1.0E-13 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS10595 7afafc85f4f23e4c0ad9534921c74d5b 368 SUPERFAMILY SSF51412 1 69 1.68E-47 T 28-03-2018 CU254_RS10595 7afafc85f4f23e4c0ad9534921c74d5b 368 SUPERFAMILY SSF51412 124 361 1.68E-47 T 28-03-2018 CU254_RS10595 7afafc85f4f23e4c0ad9534921c74d5b 368 Pfam PF03060 Nitronate monooxygenase 14 355 2.3E-43 T 28-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CU254_RS10595 7afafc85f4f23e4c0ad9534921c74d5b 368 Gene3D G3DSA:3.20.20.70 1 366 5.2E-39 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS38235 cb572b4a595c238596da1d269caca16b 255 Pfam PF00106 short chain dehydrogenase 6 188 3.3E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS38235 cb572b4a595c238596da1d269caca16b 255 Gene3D G3DSA:3.40.50.720 2 252 1.1E-51 T 28-03-2018 CU254_RS38235 cb572b4a595c238596da1d269caca16b 255 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 179 0.0013 T 28-03-2018 CU254_RS38235 cb572b4a595c238596da1d269caca16b 255 SUPERFAMILY SSF51735 5 243 4.57E-56 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS38235 cb572b4a595c238596da1d269caca16b 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 9.5E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS38235 cb572b4a595c238596da1d269caca16b 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 9.5E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS38235 cb572b4a595c238596da1d269caca16b 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 9.5E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS38235 cb572b4a595c238596da1d269caca16b 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 2.0E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS38235 cb572b4a595c238596da1d269caca16b 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 2.0E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS38235 cb572b4a595c238596da1d269caca16b 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 2.0E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS38235 cb572b4a595c238596da1d269caca16b 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 2.0E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS38235 cb572b4a595c238596da1d269caca16b 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 2.0E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS38235 cb572b4a595c238596da1d269caca16b 255 PIRSF PIRSF000126 1 255 1.4E-67 T 28-03-2018 CU254_RS35030 3f48473dfe75d426e4ba656340a5cf6c 448 SUPERFAMILY SSF56601 17 315 7.4E-72 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CU254_RS35030 3f48473dfe75d426e4ba656340a5cf6c 448 Gene3D G3DSA:3.40.710.10 19 333 1.2E-72 T 28-03-2018 CU254_RS35030 3f48473dfe75d426e4ba656340a5cf6c 448 Pfam PF00144 Beta-lactamase 20 315 2.8E-59 T 28-03-2018 IPR001466 Beta-lactamase-related CU254_RS15480 4968363fce788565a348cd1963e67252 219 SUPERFAMILY SSF53271 13 216 4.98E-41 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CU254_RS15480 4968363fce788565a348cd1963e67252 219 Pfam PF00156 Phosphoribosyl transferase domain 16 205 2.5E-24 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CU254_RS15480 4968363fce788565a348cd1963e67252 219 Gene3D G3DSA:3.40.50.2020 12 219 2.4E-32 T 28-03-2018 CU254_RS11610 c822a917d710be2c1db33859955d5377 148 Pfam PF10756 Bacterial PH domain 72 139 3.7E-20 T 28-03-2018 IPR019692 Protein of unknown function DUF2581 CU254_RS17285 aaa7fd7132bf77ef99d27ee3d79de655 452 Gene3D G3DSA:1.20.1250.20 55 248 1.2E-18 T 28-03-2018 CU254_RS17285 aaa7fd7132bf77ef99d27ee3d79de655 452 Pfam PF07690 Major Facilitator Superfamily 76 400 1.5E-22 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS17285 aaa7fd7132bf77ef99d27ee3d79de655 452 Gene3D G3DSA:1.20.1250.20 255 448 2.7E-15 T 28-03-2018 CU254_RS17285 aaa7fd7132bf77ef99d27ee3d79de655 452 SUPERFAMILY SSF103473 48 436 1.7E-42 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS35020 da89e9c100a0ae1884c6637c944cfb7e 468 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 14 441 8.1E-50 T 28-03-2018 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 CU254_RS35020 da89e9c100a0ae1884c6637c944cfb7e 468 PIRSF PIRSF002744 2 459 2.1E-89 T 28-03-2018 IPR026030 Purine-cytosine permease Fcy2/21/22 GO:0005215|GO:0016021|GO:0055085 CU254_RS25930 46ba295f947b744914b4ac61fe9ddd97 603 Pfam PF00561 alpha/beta hydrolase fold 124 287 1.6E-14 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS25930 46ba295f947b744914b4ac61fe9ddd97 603 SUPERFAMILY SSF53474 82 269 4.16E-15 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS25930 46ba295f947b744914b4ac61fe9ddd97 603 Pfam PF08386 TAP-like protein 489 569 3.6E-11 T 28-03-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal CU254_RS25930 46ba295f947b744914b4ac61fe9ddd97 603 Gene3D G3DSA:3.40.50.1820 29 567 3.8E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS24555 67af4829598d7a79efe404480299888b 158 Pfam PF04978 Protein of unknown function (DUF664) 9 154 8.0E-41 T 28-03-2018 IPR007061 Protein of unknown function DUF664 CU254_RS24555 67af4829598d7a79efe404480299888b 158 SUPERFAMILY SSF109854 3 153 5.95E-39 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CU254_RS24555 67af4829598d7a79efe404480299888b 158 Gene3D G3DSA:1.20.120.450 1 158 6.2E-33 T 28-03-2018 CU254_RS24080 40a34c44baae809071a5af794ea90b6f 111 Pfam PF01638 HxlR-like helix-turn-helix 15 103 1.3E-29 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type CU254_RS24080 40a34c44baae809071a5af794ea90b6f 111 SUPERFAMILY SSF46785 4 102 1.58E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS24080 40a34c44baae809071a5af794ea90b6f 111 Gene3D G3DSA:1.10.10.10 13 104 2.7E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS30330 1f2233203dcb68df057c401b297e97bd 78 Gene3D G3DSA:1.10.10.10 43 78 4.7E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS10845 81a2463f13df503c513687f87f31c74f 325 SUPERFAMILY SSF161098 188 312 1.64E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS10845 81a2463f13df503c513687f87f31c74f 325 SUPERFAMILY SSF161098 90 159 1.64E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS10845 81a2463f13df503c513687f87f31c74f 325 Gene3D G3DSA:1.10.3720.10 7 325 5.8E-37 T 28-03-2018 CU254_RS10845 81a2463f13df503c513687f87f31c74f 325 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 324 6.3E-36 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS07505 582395167114f49eea983d4b6b1f4e3d 324 Gene3D G3DSA:3.20.20.100 2 316 1.3E-61 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS07505 582395167114f49eea983d4b6b1f4e3d 324 SUPERFAMILY SSF51430 4 309 3.93E-63 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS07505 582395167114f49eea983d4b6b1f4e3d 324 Pfam PF00248 Aldo/keto reductase family 7 297 7.4E-45 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS20985 2552bfa718dde4d91e50a26840d9e25c 247 SUPERFAMILY SSF53474 4 245 1.55E-40 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS20985 2552bfa718dde4d91e50a26840d9e25c 247 Pfam PF01738 Dienelactone hydrolase family 16 246 4.4E-48 T 28-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 CU254_RS20985 2552bfa718dde4d91e50a26840d9e25c 247 Gene3D G3DSA:3.40.50.1820 1 245 3.6E-35 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS01275 959b9a0fd8c06cad6c844fc33ee4342f 307 Gene3D G3DSA:1.10.12.10 247 295 8.8E-16 T 28-03-2018 IPR014748 Crontonase, C-terminal CU254_RS01275 959b9a0fd8c06cad6c844fc33ee4342f 307 Gene3D G3DSA:3.90.226.10 7 246 1.2E-64 T 28-03-2018 CU254_RS01275 959b9a0fd8c06cad6c844fc33ee4342f 307 Pfam PF00378 Enoyl-CoA hydratase/isomerase 38 302 1.4E-51 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CU254_RS01275 959b9a0fd8c06cad6c844fc33ee4342f 307 Hamap MF_01934 1,4-dihydroxy-2-naphthoyl-CoA synthase [menB]. 15 306 52.743 T 28-03-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 CU254_RS01275 959b9a0fd8c06cad6c844fc33ee4342f 307 TIGRFAM TIGR01929 menB: naphthoate synthase 23 302 1.2E-126 T 28-03-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 CU254_RS01275 959b9a0fd8c06cad6c844fc33ee4342f 307 SUPERFAMILY SSF52096 37 304 9.58E-74 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS35930 9e9955734d69ed9f266e6cba9e3398d6 501 Pfam PF12821 Threonine/Serine exporter, ThrE 348 467 7.3E-16 T 28-03-2018 IPR024528 Threonine/Serine exporter, ThrE CU254_RS35930 9e9955734d69ed9f266e6cba9e3398d6 501 Pfam PF06738 Putative threonine/serine exporter 74 317 2.5E-61 T 28-03-2018 IPR010619 Putative threonine/serine exporter CU254_RS40565 0075eec7e4c19d2203f29bb0333c43c3 135 Pfam PF04686 Streptomyces sporulation and cell division protein, SsgA 22 119 1.7E-30 T 28-03-2018 IPR006776 Sporulation-specific cell division protein SsgB GO:0051301 CU254_RS31940 18f7178cd0e89188bfb0d0a82dee8876 455 TIGRFAM TIGR02946 acyl_WS_DGAT: acyltransferase, WS/DGAT/MGAT 7 451 2.7E-149 T 28-03-2018 IPR014292 Acyltransferase, WS/DGAT/MGAT GO:0016746|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CU254_RS31940 18f7178cd0e89188bfb0d0a82dee8876 455 Gene3D G3DSA:3.30.559.10 22 183 2.4E-5 T 28-03-2018 CU254_RS31940 18f7178cd0e89188bfb0d0a82dee8876 455 SUPERFAMILY SSF52777 51 152 1.63E-6 T 28-03-2018 CU254_RS31940 18f7178cd0e89188bfb0d0a82dee8876 455 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 7 263 2.6E-79 T 28-03-2018 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CU254_RS31940 18f7178cd0e89188bfb0d0a82dee8876 455 Pfam PF06974 Protein of unknown function (DUF1298) 304 449 3.1E-38 T 28-03-2018 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CU254_RS29790 b9b62f50364cb9ee2fbc115e8d368426 162 Pfam PF02698 DUF218 domain 13 132 1.7E-18 T 28-03-2018 IPR003848 Domain of unknown function DUF218 CU254_RS29790 b9b62f50364cb9ee2fbc115e8d368426 162 Gene3D G3DSA:3.40.50.620 7 136 3.9E-18 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS17725 3113c9bafb4fe407ed691c433d16c795 166 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 3 158 33.95 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CU254_RS17725 3113c9bafb4fe407ed691c433d16c795 166 Pfam PF01625 Peptide methionine sulfoxide reductase 5 152 2.8E-58 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CU254_RS17725 3113c9bafb4fe407ed691c433d16c795 166 SUPERFAMILY SSF55068 3 160 1.11E-65 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CU254_RS17725 3113c9bafb4fe407ed691c433d16c795 166 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 4 152 1.4E-50 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CU254_RS17725 3113c9bafb4fe407ed691c433d16c795 166 Gene3D G3DSA:3.30.1060.10 2 166 4.6E-67 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CU254_RS33695 2c0931cb34db4cb94eb8748b361d00b7 201 Gene3D G3DSA:3.40.50.150 4 184 9.2E-20 T 28-03-2018 CU254_RS33695 2c0931cb34db4cb94eb8748b361d00b7 201 Pfam PF13649 Methyltransferase domain 40 134 5.7E-10 T 28-03-2018 CU254_RS33695 2c0931cb34db4cb94eb8748b361d00b7 201 SUPERFAMILY SSF53335 1 147 7.83E-22 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS16540 c05b2b39efcb158f26528a2f2aa57566 133 Gene3D G3DSA:3.30.750.24 12 123 9.4E-15 T 28-03-2018 IPR002645 STAS domain CU254_RS16540 c05b2b39efcb158f26528a2f2aa57566 133 Pfam PF13466 STAS domain 26 106 7.0E-14 T 28-03-2018 IPR002645 STAS domain CU254_RS16540 c05b2b39efcb158f26528a2f2aa57566 133 SUPERFAMILY SSF52091 20 119 5.3E-15 T 28-03-2018 IPR002645 STAS domain CU254_RS39775 98e1c3f9aec89b364ce012cfe59b2711 323 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 50 316 1.5E-57 T 28-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 CU254_RS39775 98e1c3f9aec89b364ce012cfe59b2711 323 Gene3D G3DSA:3.40.190.10 204 320 8.3E-18 T 28-03-2018 CU254_RS39775 98e1c3f9aec89b364ce012cfe59b2711 323 Gene3D G3DSA:3.40.190.10 43 203 2.0E-25 T 28-03-2018 CU254_RS39775 98e1c3f9aec89b364ce012cfe59b2711 323 SUPERFAMILY SSF53850 51 322 2.58E-60 T 28-03-2018 CU254_RS17485 300a708acf8990b3bcf00376cb00d705 293 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 46 254 1.3E-52 T 28-03-2018 IPR018713 Domain of unknown function DUF2236 CU254_RS13305 c2b26592a7a45507aa194503e4893f4d 111 Pfam PF13466 STAS domain 31 98 3.6E-8 T 28-03-2018 IPR002645 STAS domain CU254_RS13305 c2b26592a7a45507aa194503e4893f4d 111 Gene3D G3DSA:3.30.750.24 12 111 8.3E-8 T 28-03-2018 IPR002645 STAS domain CU254_RS13305 c2b26592a7a45507aa194503e4893f4d 111 SUPERFAMILY SSF52091 14 108 2.94E-12 T 28-03-2018 IPR002645 STAS domain CU254_RS20285 86355d2ddc53228a55bfcacabef97b94 255 Gene3D G3DSA:3.40.50.10320 2 253 7.6E-47 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CU254_RS20285 86355d2ddc53228a55bfcacabef97b94 255 Pfam PF02585 GlcNAc-PI de-N-acetylase 18 144 1.5E-22 T 28-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 CU254_RS20285 86355d2ddc53228a55bfcacabef97b94 255 SUPERFAMILY SSF102588 15 241 1.57E-41 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CU254_RS22660 314d64eb18fb6ade217f56036b5d3f61 159 Gene3D G3DSA:3.30.420.10 5 157 8.6E-50 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS22660 314d64eb18fb6ade217f56036b5d3f61 159 Hamap MF_00042 Ribonuclease H [rnhA]. 6 155 32.785 T 28-03-2018 IPR022892 Ribonuclease HI GO:0004523 CU254_RS22660 314d64eb18fb6ade217f56036b5d3f61 159 SUPERFAMILY SSF53098 7 146 3.41E-54 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS22660 314d64eb18fb6ade217f56036b5d3f61 159 Pfam PF00075 RNase H 7 146 1.3E-51 T 28-03-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 CU254_RS20190 46fc7919ef05cfd042059ff7ff989c7b 272 Gene3D G3DSA:3.40.50.720 1 145 1.9E-18 T 28-03-2018 CU254_RS20190 46fc7919ef05cfd042059ff7ff989c7b 272 Gene3D G3DSA:3.90.25.10 146 268 8.7E-5 T 28-03-2018 CU254_RS20190 46fc7919ef05cfd042059ff7ff989c7b 272 Pfam PF13460 NAD(P)H-binding 6 183 1.9E-16 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS20190 46fc7919ef05cfd042059ff7ff989c7b 272 SUPERFAMILY SSF51735 2 251 8.24E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS12620 9285818659158b32569cedbc3d599f72 102 Gene3D G3DSA:1.10.287.1060 1 93 5.8E-7 T 28-03-2018 CU254_RS33725 e4790cef45aeb9e55c2f7e787a56c636 132 Pfam PF00293 NUDIX domain 14 110 1.6E-10 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CU254_RS33725 e4790cef45aeb9e55c2f7e787a56c636 132 SUPERFAMILY SSF55811 8 111 2.03E-19 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CU254_RS33725 e4790cef45aeb9e55c2f7e787a56c636 132 Gene3D G3DSA:3.90.79.10 3 128 3.2E-17 T 28-03-2018 CU254_RS28660 01ba10ac174206837ac7e00088add869 510 Pfam PF05872 Bacterial protein of unknown function (DUF853) 33 507 1.6E-193 T 28-03-2018 IPR033186 Helicase HerA-like C-terminal CU254_RS28660 01ba10ac174206837ac7e00088add869 510 SUPERFAMILY SSF52540 29 398 3.02E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS28660 01ba10ac174206837ac7e00088add869 510 Gene3D G3DSA:3.40.50.300 9 380 7.4E-26 T 28-03-2018 CU254_RS28660 01ba10ac174206837ac7e00088add869 510 Gene3D G3DSA:3.40.50.720 381 495 0.029 T 28-03-2018 CU254_RS37120 67715829b06a986defadb4c8a9536280 164 Gene3D G3DSA:3.40.50.300 1 162 6.0E-16 T 28-03-2018 CU254_RS37120 67715829b06a986defadb4c8a9536280 164 Pfam PF03029 Conserved hypothetical ATP binding protein 44 125 3.4E-9 T 28-03-2018 IPR004130 GPN-loop GTPase CU254_RS37120 67715829b06a986defadb4c8a9536280 164 SUPERFAMILY SSF52540 2 143 2.62E-15 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS40040 36308de7cf5d0b745ef1732391007ed0 195 Pfam PF01169 Uncharacterized protein family UPF0016 6 76 7.8E-15 T 28-03-2018 IPR001727 Gdt1 family CU254_RS40040 36308de7cf5d0b745ef1732391007ed0 195 Pfam PF01169 Uncharacterized protein family UPF0016 111 186 1.4E-17 T 28-03-2018 IPR001727 Gdt1 family CU254_RS07540 dbe72b3547fe558a659e94812a46d0ce 269 SUPERFAMILY SSF100950 3 262 8.97E-76 T 28-03-2018 CU254_RS07540 dbe72b3547fe558a659e94812a46d0ce 269 Gene3D G3DSA:3.40.1080.10 2 246 5.0E-55 T 28-03-2018 CU254_RS07540 dbe72b3547fe558a659e94812a46d0ce 269 SMART SM00882 4 224 7.9E-47 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CU254_RS07540 dbe72b3547fe558a659e94812a46d0ce 269 Pfam PF01144 Coenzyme A transferase 6 223 3.7E-27 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CU254_RS06985 1823738b7b5a0ac885acd5f2efc6ccbe 162 Gene3D G3DSA:1.10.260.40 38 162 6.7E-10 T 28-03-2018 CU254_RS06985 1823738b7b5a0ac885acd5f2efc6ccbe 162 Gene3D G3DSA:1.10.10.60 2 37 4.7E-15 T 28-03-2018 CU254_RS06985 1823738b7b5a0ac885acd5f2efc6ccbe 162 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 51 4.4E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS06985 1823738b7b5a0ac885acd5f2efc6ccbe 162 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 7 20 1.8E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS06985 1823738b7b5a0ac885acd5f2efc6ccbe 162 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 51 1.8E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS06985 1823738b7b5a0ac885acd5f2efc6ccbe 162 SUPERFAMILY SSF46689 3 67 3.13E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS14730 5086fa21a95f82d40fbf6c48596c4f40 467 Pfam PF05133 Phage portal protein, SPP1 Gp6-like 83 410 2.3E-11 T 28-03-2018 IPR021145 Portal protein CU254_RS19040 d461d4d75c5bcae26461bea594c60339 213 Gene3D G3DSA:3.30.565.10 38 211 5.0E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS19040 d461d4d75c5bcae26461bea594c60339 213 SUPERFAMILY SSF55874 34 186 1.07E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS01230 abad821e188c0e096a8f754ff0c30ddc 330 TIGRFAM TIGR03144 cytochr_II_ccsB: cytochrome c-type biogenesis protein CcsB 94 327 1.1E-71 T 28-03-2018 IPR017562 Cytochrome c-type biogenesis protein CcsA GO:0017004 CU254_RS01230 abad821e188c0e096a8f754ff0c30ddc 330 Pfam PF01578 Cytochrome C assembly protein 116 324 3.5E-46 T 28-03-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 CU254_RS27820 663599a9fbe4d979cedcc47c493ad179 345 Pfam PF00795 Carbon-nitrogen hydrolase 16 267 6.8E-48 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CU254_RS27820 663599a9fbe4d979cedcc47c493ad179 345 SUPERFAMILY SSF56317 11 275 1.22E-56 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CU254_RS27820 663599a9fbe4d979cedcc47c493ad179 345 Hamap MF_01242 Aliphatic amidase [amiE]. 1 340 84.098 T 28-03-2018 IPR023719 Aliphatic amidase GO:0004040 KEGG: 00330+3.5.1.4|KEGG: 00360+3.5.1.4|KEGG: 00380+3.5.1.4|KEGG: 00627+3.5.1.4|KEGG: 00643+3.5.1.4|MetaCyc: PWY-3161|MetaCyc: PWY-5025|MetaCyc: PWY-581|MetaCyc: PWY-7308 CU254_RS27820 663599a9fbe4d979cedcc47c493ad179 345 Gene3D G3DSA:3.60.110.10 1 345 1.2E-69 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CU254_RS02475 492970abaad44cb9c9d20e14a5cfe5ae 181 Gene3D G3DSA:1.20.120.450 61 178 2.1E-21 T 28-03-2018 CU254_RS02475 492970abaad44cb9c9d20e14a5cfe5ae 181 Gene3D G3DSA:1.20.120.450 1 48 4.2E-9 T 28-03-2018 CU254_RS02475 492970abaad44cb9c9d20e14a5cfe5ae 181 Pfam PF12867 DinB superfamily 12 170 1.8E-18 T 28-03-2018 IPR024775 DinB-like domain CU254_RS02475 492970abaad44cb9c9d20e14a5cfe5ae 181 SUPERFAMILY SSF109854 75 178 1.17E-19 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CU254_RS02475 492970abaad44cb9c9d20e14a5cfe5ae 181 SUPERFAMILY SSF109854 3 43 1.17E-19 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CU254_RS41755 84a2d53cee66a941f0f497391000684e 236 SUPERFAMILY SSF88697 75 187 1.34E-11 T 28-03-2018 IPR015947 PUA-like domain CU254_RS41755 84a2d53cee66a941f0f497391000684e 236 Gene3D G3DSA:2.30.130.30 74 180 3.0E-21 T 28-03-2018 CU254_RS02230 65799ee90923f22bf73770b3fce09604 278 SUPERFAMILY SSF53474 29 257 1.15E-22 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS02230 65799ee90923f22bf73770b3fce09604 278 Pfam PF12740 Chlorophyllase enzyme 32 139 5.7E-10 T 28-03-2018 IPR017395 Chlorophyllase GO:0015996|GO:0047746 KEGG: 00860+3.1.1.14|MetaCyc: PWY-5098|MetaCyc: PWY-6927|MetaCyc: PWY-7164 CU254_RS02230 65799ee90923f22bf73770b3fce09604 278 Gene3D G3DSA:3.40.50.1820 2 270 3.7E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS41580 efab98591439f785752b522a053f1ea2 318 Gene3D G3DSA:2.40.440.10 191 318 2.2E-21 T 28-03-2018 CU254_RS41580 efab98591439f785752b522a053f1ea2 318 Pfam PF03734 L,D-transpeptidase catalytic domain 199 317 6.8E-13 T 28-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CU254_RS41580 efab98591439f785752b522a053f1ea2 318 SUPERFAMILY SSF141523 196 317 2.62E-20 T 28-03-2018 CU254_RS28290 65cc47315bdd74cfea0fd0c88aa0a1c2 327 SUPERFAMILY SSF51556 2 281 8.17E-44 T 28-03-2018 IPR032466 Metal-dependent hydrolase CU254_RS28290 65cc47315bdd74cfea0fd0c88aa0a1c2 327 Gene3D G3DSA:3.20.20.140 1 295 2.2E-35 T 28-03-2018 CU254_RS28290 65cc47315bdd74cfea0fd0c88aa0a1c2 327 Pfam PF04909 Amidohydrolase 3 280 1.3E-35 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CU254_RS03035 d6f0d5928cc4eeff207e29fd3a470e27 423 Pfam PF00999 Sodium/hydrogen exchanger family 16 398 8.1E-51 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CU254_RS03035 d6f0d5928cc4eeff207e29fd3a470e27 423 Gene3D G3DSA:1.20.91.10 250 336 2.7E-20 T 28-03-2018 CU254_RS12210 4750b3b03ea5b644330b7fe737225521 308 SUPERFAMILY SSF54593 5 254 5.65E-41 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS12210 4750b3b03ea5b644330b7fe737225521 308 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 143 252 2.0E-15 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CU254_RS12210 4750b3b03ea5b644330b7fe737225521 308 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 15 122 7.6E-10 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CU254_RS12210 4750b3b03ea5b644330b7fe737225521 308 Gene3D G3DSA:3.10.180.10 4 133 2.2E-21 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS12210 4750b3b03ea5b644330b7fe737225521 308 Gene3D G3DSA:3.10.180.10 135 283 7.1E-34 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS15945 59ee1848c2e5314edfc47def42e2a16a 268 Hamap MF_01924 D-alanyl-D-alanine dipeptidase [ddpX]. 37 257 30.683 T 28-03-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 CU254_RS15945 59ee1848c2e5314edfc47def42e2a16a 268 Gene3D G3DSA:3.30.1380.10 34 259 2.5E-65 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CU254_RS15945 59ee1848c2e5314edfc47def42e2a16a 268 Pfam PF01427 D-ala-D-ala dipeptidase 37 160 2.2E-18 T 28-03-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 CU254_RS15945 59ee1848c2e5314edfc47def42e2a16a 268 Pfam PF01427 D-ala-D-ala dipeptidase 191 257 3.6E-11 T 28-03-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 CU254_RS15945 59ee1848c2e5314edfc47def42e2a16a 268 PIRSF PIRSF026671 10 263 1.2E-65 T 28-03-2018 IPR000755 D-alanyl-D-alanine dipeptidase GO:0005618|GO:0006508|GO:0008237|GO:0016805 MetaCyc: PWY-6454|MetaCyc: PWY-6455 CU254_RS15945 59ee1848c2e5314edfc47def42e2a16a 268 SUPERFAMILY SSF55166 36 258 1.02E-55 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CU254_RS29430 0351bbecf074cd63099ca82271eeff18 301 Pfam PF01636 Phosphotransferase enzyme family 39 211 6.9E-9 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CU254_RS29430 0351bbecf074cd63099ca82271eeff18 301 Gene3D G3DSA:1.10.510.10 45 279 2.4E-8 T 28-03-2018 CU254_RS29430 0351bbecf074cd63099ca82271eeff18 301 SUPERFAMILY SSF56112 2 277 5.36E-21 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS12520 4ec311d12eed90850edfef0ffa0c19e3 198 Gene3D G3DSA:3.40.630.30 1 177 5.2E-21 T 28-03-2018 CU254_RS12520 4ec311d12eed90850edfef0ffa0c19e3 198 Pfam PF13302 Acetyltransferase (GNAT) domain 2 131 9.2E-12 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS12520 4ec311d12eed90850edfef0ffa0c19e3 198 SUPERFAMILY SSF55729 1 155 1.17E-21 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS04740 e00dda46c58bfe591dfe8c3ab26ed3ec 162 Pfam PF06271 RDD family 43 138 4.0E-7 T 28-03-2018 IPR010432 RDD CU254_RS04740 e00dda46c58bfe591dfe8c3ab26ed3ec 162 PIRSF PIRSF021697 1 161 8.5E-37 T 28-03-2018 IPR016795 Uncharacterised conserved protein UCP021697, membrane CU254_RS18095 6e33f1701d860608cabae3a8a384fec4 652 Gene3D G3DSA:3.40.50.410 459 626 2.0E-15 T 28-03-2018 IPR002035 von Willebrand factor, type A CU254_RS18095 6e33f1701d860608cabae3a8a384fec4 652 SMART SM00327 465 647 2.7E-11 T 28-03-2018 IPR002035 von Willebrand factor, type A CU254_RS18095 6e33f1701d860608cabae3a8a384fec4 652 Gene3D G3DSA:1.20.1170.10 140 410 4.3E-4 T 28-03-2018 CU254_RS18095 6e33f1701d860608cabae3a8a384fec4 652 SUPERFAMILY SSF53300 467 639 3.12E-16 T 28-03-2018 IPR002035 von Willebrand factor, type A CU254_RS21555 9257fa382ea014219a1b979280221b9f 298 Gene3D G3DSA:3.90.1200.10 109 264 5.7E-20 T 28-03-2018 CU254_RS21555 9257fa382ea014219a1b979280221b9f 298 SUPERFAMILY SSF56112 16 263 1.46E-43 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS21555 9257fa382ea014219a1b979280221b9f 298 Gene3D G3DSA:3.30.200.20 8 100 6.0E-4 T 28-03-2018 CU254_RS21555 9257fa382ea014219a1b979280221b9f 298 Pfam PF01636 Phosphotransferase enzyme family 29 256 2.3E-34 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CU254_RS39215 4c58e6652f2a4347b7d0d4d9a68f6879 375 SUPERFAMILY SSF81665 205 253 9.29E-5 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CU254_RS39215 4c58e6652f2a4347b7d0d4d9a68f6879 375 SUPERFAMILY SSF81665 12 70 9.29E-5 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CU254_RS39215 4c58e6652f2a4347b7d0d4d9a68f6879 375 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 31 259 5.6E-56 T 28-03-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal CU254_RS39215 4c58e6652f2a4347b7d0d4d9a68f6879 375 Pfam PF02096 60Kd inner membrane protein 32 260 1.5E-52 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CU254_RS29325 852f9088a2cb494a018542129f69e265 332 PIRSF PIRSF016838 1 53 0.028 T 28-03-2018 IPR028349 Protein PafC CU254_RS29325 852f9088a2cb494a018542129f69e265 332 PIRSF PIRSF016838 68 320 4.4E-22 T 28-03-2018 IPR028349 Protein PafC CU254_RS29325 852f9088a2cb494a018542129f69e265 332 Pfam PF08279 HTH domain 7 62 5.0E-11 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 CU254_RS29325 852f9088a2cb494a018542129f69e265 332 Gene3D G3DSA:1.10.10.10 2 66 3.3E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS29325 852f9088a2cb494a018542129f69e265 332 SUPERFAMILY SSF46785 5 64 2.12E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS29325 852f9088a2cb494a018542129f69e265 332 Pfam PF13280 WYL domain 143 313 1.0E-35 T 28-03-2018 IPR026881 WYL domain CU254_RS37265 8c7ff6ed13d1bb7bfad0512ed971b6c1 338 Gene3D G3DSA:3.60.21.10 3 268 3.4E-46 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CU254_RS37265 8c7ff6ed13d1bb7bfad0512ed971b6c1 338 SUPERFAMILY SSF56300 2 132 1.77E-35 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CU254_RS37265 8c7ff6ed13d1bb7bfad0512ed971b6c1 338 SUPERFAMILY SSF56300 176 264 1.77E-35 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CU254_RS37265 8c7ff6ed13d1bb7bfad0512ed971b6c1 338 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 3 261 6.1E-62 T 28-03-2018 IPR019079 Capsule synthesis protein, CapA CU254_RS37265 8c7ff6ed13d1bb7bfad0512ed971b6c1 338 SMART SM00854 3 262 2.6E-73 T 28-03-2018 IPR019079 Capsule synthesis protein, CapA CU254_RS18270 475239305929b1a3b0b50ff2ad5b897d 342 Gene3D G3DSA:2.120.10.10 154 338 1.7E-17 T 28-03-2018 CU254_RS18270 475239305929b1a3b0b50ff2ad5b897d 342 Gene3D G3DSA:2.120.10.10 16 153 2.4E-17 T 28-03-2018 CU254_RS18270 475239305929b1a3b0b50ff2ad5b897d 342 SUPERFAMILY SSF110296 27 310 1.44E-30 T 28-03-2018 CU254_RS04710 0a4f0d7f04ebd99c234200f9d1f81397 234 Gene3D G3DSA:3.10.290.30 40 220 1.0E-58 T 28-03-2018 IPR024047 Protein MM3350-like domain CU254_RS04710 0a4f0d7f04ebd99c234200f9d1f81397 234 SUPERFAMILY SSF159941 46 219 2.09E-58 T 28-03-2018 IPR024047 Protein MM3350-like domain CU254_RS04710 0a4f0d7f04ebd99c234200f9d1f81397 234 Pfam PF07929 Plasmid pRiA4b ORF-3-like protein 47 216 3.0E-58 T 28-03-2018 IPR012912 Plasmid pRiA4b, Orf3 CU254_RS04365 7a2d10e0d9abe04b78dde36fe5801082 246 Gene3D G3DSA:3.30.450.20 48 152 2.5E-10 T 28-03-2018 CU254_RS04365 7a2d10e0d9abe04b78dde36fe5801082 246 Gene3D G3DSA:3.30.450.20 153 220 6.1E-7 T 28-03-2018 CU254_RS42450 33a01b581e15c458143836161f909d65 508 Gene3D G3DSA:3.40.50.300 321 472 0.001 T 28-03-2018 CU254_RS42450 33a01b581e15c458143836161f909d65 508 Pfam PF13521 AAA domain 329 491 5.9E-23 T 28-03-2018 CU254_RS06660 86d3c44ae3aae6432562fc8b978bfb3d 105 Pfam PF00893 Small Multidrug Resistance protein 1 93 4.0E-23 T 28-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 CU254_RS06660 86d3c44ae3aae6432562fc8b978bfb3d 105 SUPERFAMILY SSF103481 5 104 2.62E-19 T 28-03-2018 CU254_RS19505 f964e3312891b6ed55c77c466fd037d2 602 Gene3D G3DSA:3.10.105.10 303 517 1.7E-43 T 28-03-2018 CU254_RS19505 f964e3312891b6ed55c77c466fd037d2 602 SUPERFAMILY SSF53850 32 548 1.27E-115 T 28-03-2018 CU254_RS19505 f964e3312891b6ed55c77c466fd037d2 602 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 79 453 2.2E-87 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CU254_RS19505 f964e3312891b6ed55c77c466fd037d2 602 Gene3D G3DSA:3.40.190.10 152 302 1.9E-35 T 28-03-2018 CU254_RS19505 f964e3312891b6ed55c77c466fd037d2 602 Gene3D G3DSA:3.90.76.10 52 151 1.9E-27 T 28-03-2018 CU254_RS19505 f964e3312891b6ed55c77c466fd037d2 602 PIRSF PIRSF002741 2 549 1.4E-92 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CU254_RS10790 d99f6d2801b4a25580964ae4cbb1c3f1 477 Pfam PF13520 Amino acid permease 29 448 1.4E-53 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CU254_RS10790 d99f6d2801b4a25580964ae4cbb1c3f1 477 PIRSF PIRSF006060 8 477 8.7E-90 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CU254_RS15235 101698a470b862daabff835fb240076b 216 Gene3D G3DSA:3.40.50.1860 9 94 0.053 T 28-03-2018 CU254_RS15235 101698a470b862daabff835fb240076b 216 Gene3D G3DSA:3.40.50.1860 103 204 2.5E-7 T 28-03-2018 CU254_RS35230 baf03dc6fdacdee673a9cad4234c1201 93 SUPERFAMILY SSF54285 12 91 8.97E-15 T 28-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp CU254_RS35230 baf03dc6fdacdee673a9cad4234c1201 93 Pfam PF02597 ThiS family 15 93 1.5E-13 T 28-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 CU254_RS35230 baf03dc6fdacdee673a9cad4234c1201 93 Gene3D G3DSA:3.10.20.30 13 93 1.1E-22 T 28-03-2018 IPR012675 Beta-grasp domain CU254_RS05830 2b9eab8a90039e54bdd11236c2b976fe 398 Pfam PF01757 Acyltransferase family 21 377 6.3E-23 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CU254_RS11665 e35655017e6cde125720687071a0accb 1488 Gene3D G3DSA:3.40.50.300 1 744 3.6E-5 T 28-03-2018 CU254_RS11665 e35655017e6cde125720687071a0accb 1488 Gene3D G3DSA:1.10.287.620 1006 1194 6.7E-7 T 28-03-2018 CU254_RS11665 e35655017e6cde125720687071a0accb 1488 Gene3D G3DSA:1.20.120.330 748 924 2.6E-4 T 28-03-2018 CU254_RS19875 bc9857652d68c358a42b97104ca087d7 315 Gene3D G3DSA:3.40.30.10 145 238 1.1E-7 T 28-03-2018 CU254_RS19875 bc9857652d68c358a42b97104ca087d7 315 Pfam PF06999 Sucrase/ferredoxin-like 131 204 1.1E-13 T 28-03-2018 IPR009737 Thioredoxin-like ferredoxin CU254_RS12185 8092b2c86ecb98ae313f4a2869830891 172 Pfam PF07883 Cupin domain 76 150 8.3E-15 T 28-03-2018 IPR013096 Cupin 2, conserved barrel CU254_RS12185 8092b2c86ecb98ae313f4a2869830891 172 SUPERFAMILY SSF51182 19 164 1.17E-23 T 28-03-2018 IPR011051 RmlC-like cupin domain CU254_RS12185 8092b2c86ecb98ae313f4a2869830891 172 Gene3D G3DSA:2.60.120.10 35 169 3.0E-20 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS17425 359f551cea8e6bdbdacfac4f36523dac 459 Pfam PF03559 NDP-hexose 2,3-dehydratase 23 220 1.3E-67 T 28-03-2018 IPR005212 NDP-hexose 2,3-dehydratase CU254_RS17425 359f551cea8e6bdbdacfac4f36523dac 459 Pfam PF03559 NDP-hexose 2,3-dehydratase 255 449 1.3E-56 T 28-03-2018 IPR005212 NDP-hexose 2,3-dehydratase CU254_RS38790 d3e767e182bad48726944c3bb94f4be6 246 Pfam PF12730 ABC-2 family transporter protein 3 174 3.5E-6 T 28-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 CU254_RS18280 3c5409dcba21bc737cc760b45fa096f0 326 Gene3D G3DSA:1.10.10.10 2 57 5.0E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS18280 3c5409dcba21bc737cc760b45fa096f0 326 PIRSF PIRSF016838 1 322 2.9E-116 T 28-03-2018 IPR028349 Protein PafC CU254_RS18280 3c5409dcba21bc737cc760b45fa096f0 326 Pfam PF13280 WYL domain 147 313 1.9E-31 T 28-03-2018 IPR026881 WYL domain CU254_RS24035 c785a93777ed4df60cada43857e40200 132 Gene3D G3DSA:3.30.160.160 65 105 0.0014 T 28-03-2018 IPR010879 Domain of unknown function DUF1508 CU254_RS24675 5358dca1a23101f6359f865212a0be12 133 Pfam PF11239 Protein of unknown function (DUF3040) 1 87 1.8E-30 T 28-03-2018 IPR021401 Protein of unknown function DUF3040 CU254_RS15645 b82dc335c17fee530c62202a2870dd0a 372 SUPERFAMILY SSF55931 2 345 2.55E-76 T 28-03-2018 CU254_RS15645 b82dc335c17fee530c62202a2870dd0a 372 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 6 286 5.5E-42 T 28-03-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CU254_RS15645 b82dc335c17fee530c62202a2870dd0a 372 Hamap MF_01609 Glutamate--cysteine ligase [gshA]. 1 372 66.565 T 28-03-2018 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CU254_RS15645 b82dc335c17fee530c62202a2870dd0a 372 TIGRFAM TIGR02050 gshA_cyan_rel: carboxylate-amine ligase, YbdK family 5 291 6.1E-68 T 28-03-2018 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CU254_RS02655 db32a5a2e6149254adc11ccd1699767e 375 Pfam PF14021 Tuberculosis necrotizing toxin 281 365 1.4E-28 T 28-03-2018 IPR025331 Tuberculosis necrotizing toxin CU254_RS02575 5770aa522292fde785b162606d82dc00 229 Gene3D G3DSA:2.70.70.10 60 224 2.1E-48 T 28-03-2018 CU254_RS02575 5770aa522292fde785b162606d82dc00 229 SUPERFAMILY SSF51261 91 221 4.06E-49 T 28-03-2018 IPR011055 Duplicated hybrid motif CU254_RS02575 5770aa522292fde785b162606d82dc00 229 Pfam PF01551 Peptidase family M23 122 217 1.3E-31 T 28-03-2018 IPR016047 Peptidase M23 CU254_RS21705 bb794be012dbb6fa42b6eacd7de8dece 137 Gene3D G3DSA:3.10.129.10 1 133 3.5E-23 T 28-03-2018 CU254_RS21705 bb794be012dbb6fa42b6eacd7de8dece 137 SUPERFAMILY SSF54637 4 130 7.46E-19 T 28-03-2018 IPR029069 HotDog domain CU254_RS06335 050e631f210fa1250bcc80df7a98ded3 122 Pfam PF03779 SPW repeat 65 109 3.2E-9 T 28-03-2018 IPR005530 SPW repeat CU254_RS20855 776aa98d8319845f20a872b685db22f6 317 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 303 8.0E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS20855 776aa98d8319845f20a872b685db22f6 317 Gene3D G3DSA:1.10.3720.10 30 315 8.3E-47 T 28-03-2018 CU254_RS20855 776aa98d8319845f20a872b685db22f6 317 SUPERFAMILY SSF161098 75 301 2.75E-60 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS17885 efdac5ac2adbffa4ca554b01e9f68f3f 347 Gene3D G3DSA:3.10.580.10 196 347 1.2E-23 T 28-03-2018 CU254_RS17885 efdac5ac2adbffa4ca554b01e9f68f3f 347 SUPERFAMILY SSF54631 213 342 1.26E-20 T 28-03-2018 CU254_RS17885 efdac5ac2adbffa4ca554b01e9f68f3f 347 Pfam PF00571 CBS domain 217 272 1.8E-5 T 28-03-2018 IPR000644 CBS domain CU254_RS17885 efdac5ac2adbffa4ca554b01e9f68f3f 347 Pfam PF01595 Domain of unknown function DUF21 9 202 1.4E-42 T 28-03-2018 IPR002550 Domain of unknown function DUF21 CU254_RS34845 9c4f63421e3efeca23c496882ed751ef 202 Pfam PF05685 Putative restriction endonuclease 24 192 1.5E-21 T 28-03-2018 IPR008538 Domain of unknown function DUF820 CU254_RS34845 9c4f63421e3efeca23c496882ed751ef 202 Gene3D G3DSA:3.90.1570.10 13 201 1.7E-29 T 28-03-2018 CU254_RS34845 9c4f63421e3efeca23c496882ed751ef 202 SUPERFAMILY SSF52980 17 162 2.95E-19 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CU254_RS01445 272a5779bb0220a39791d98298885cef 253 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 225 3.0E-44 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CU254_RS01445 272a5779bb0220a39791d98298885cef 253 Gene3D G3DSA:3.90.226.10 1 253 6.2E-54 T 28-03-2018 CU254_RS01445 272a5779bb0220a39791d98298885cef 253 SUPERFAMILY SSF52096 2 247 2.4E-57 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS40300 0cce507a6919c5181956145a5b540142 243 Pfam PF01553 Acyltransferase 23 149 2.5E-29 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CU254_RS40300 0cce507a6919c5181956145a5b540142 243 Gene3D G3DSA:3.40.1130.10 6 222 6.1E-46 T 28-03-2018 CU254_RS40300 0cce507a6919c5181956145a5b540142 243 SMART SM00563 38 152 3.0E-35 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CU254_RS40300 0cce507a6919c5181956145a5b540142 243 SUPERFAMILY SSF69593 13 208 9.42E-36 T 28-03-2018 CU254_RS36730 271dafb1a47f2f53d2bf750092ec494e 165 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 36 151 4.6E-30 T 28-03-2018 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III CU254_RS33155 aa10353b198eb7a3cc47109aee0a54e8 289 Gene3D G3DSA:1.25.40.10 3 92 1.9E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS33155 aa10353b198eb7a3cc47109aee0a54e8 289 SUPERFAMILY SSF103088 185 267 1.31E-5 T 28-03-2018 IPR006665 OmpA-like domain CU254_RS33155 aa10353b198eb7a3cc47109aee0a54e8 289 Gene3D G3DSA:3.30.1330.60 140 283 1.1E-8 T 28-03-2018 IPR006665 OmpA-like domain CU254_RS03990 5f176a33dd3342913243a8630ea28afb 337 PRINTS PR00111 Alpha/beta hydrolase fold signature 91 106 6.9E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS03990 5f176a33dd3342913243a8630ea28afb 337 PRINTS PR00111 Alpha/beta hydrolase fold signature 135 148 6.9E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS03990 5f176a33dd3342913243a8630ea28afb 337 PRINTS PR00111 Alpha/beta hydrolase fold signature 149 162 6.9E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS03990 5f176a33dd3342913243a8630ea28afb 337 Gene3D G3DSA:3.40.50.1820 49 328 1.4E-46 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS03990 5f176a33dd3342913243a8630ea28afb 337 Pfam PF00561 alpha/beta hydrolase fold 69 318 6.9E-27 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS03990 5f176a33dd3342913243a8630ea28afb 337 SUPERFAMILY SSF53474 53 326 7.5E-54 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS40910 47289baadecb78026bc611b2f7e254f3 218 Pfam PF14430 Immunity protein Imm1 94 216 1.4E-20 T 28-03-2018 IPR025680 Immunity protein Imm1 CU254_RS39950 83e473562970e84e032ebe933ae55cf4 293 Pfam PF14219 Domain of unknown function (DUF4328) 99 256 4.3E-34 T 28-03-2018 IPR025565 Domain of unknown function DUF4328 CU254_RS12735 95ee70ed121f46a112be837eeba79dd3 123 Gene3D G3DSA:3.10.180.10 1 119 3.1E-17 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS12735 95ee70ed121f46a112be837eeba79dd3 123 SUPERFAMILY SSF54593 5 119 2.89E-19 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS12735 95ee70ed121f46a112be837eeba79dd3 123 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 118 1.9E-7 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CU254_RS27920 16973a9a15ffdb480f25bc1bcdaa721b 130 SUPERFAMILY SSF54909 1 113 6.43E-20 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS27920 16973a9a15ffdb480f25bc1bcdaa721b 130 Gene3D G3DSA:3.30.70.1060 1 129 4.2E-34 T 28-03-2018 CU254_RS27920 16973a9a15ffdb480f25bc1bcdaa721b 130 Pfam PF03795 YCII-related domain 1 106 5.4E-12 T 28-03-2018 IPR005545 YCII-related CU254_RS23880 6fc79c0cf7fe391242d838e4968afc1b 204 SUPERFAMILY SSF46689 14 86 5.49E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS23880 6fc79c0cf7fe391242d838e4968afc1b 204 Gene3D G3DSA:1.10.10.60 3 65 1.7E-13 T 28-03-2018 CU254_RS23880 6fc79c0cf7fe391242d838e4968afc1b 204 Gene3D G3DSA:1.10.357.10 66 203 5.2E-20 T 28-03-2018 CU254_RS23880 6fc79c0cf7fe391242d838e4968afc1b 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 65 5.2E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS37580 7d345f07ca70db8471687b83eb29d1ca 243 Gene3D G3DSA:3.40.630.30 103 242 1.5E-18 T 28-03-2018 CU254_RS37580 7d345f07ca70db8471687b83eb29d1ca 243 Pfam PF00583 Acetyltransferase (GNAT) family 141 219 2.9E-10 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS37580 7d345f07ca70db8471687b83eb29d1ca 243 SUPERFAMILY SSF55729 71 237 1.86E-21 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS20040 d2ba142b5ab139f5113f8a2a9d06ebc1 319 SUPERFAMILY SSF161098 96 304 7.06E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS20040 d2ba142b5ab139f5113f8a2a9d06ebc1 319 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 316 4.4E-35 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS20040 d2ba142b5ab139f5113f8a2a9d06ebc1 319 Gene3D G3DSA:1.10.3720.10 1 305 1.2E-34 T 28-03-2018 CU254_RS15865 612ea6992d31a99e1a4fdf562e2f97c7 199 Gene3D G3DSA:3.40.50.360 1 199 1.1E-24 T 28-03-2018 IPR029039 Flavoprotein-like domain CU254_RS15865 612ea6992d31a99e1a4fdf562e2f97c7 199 Pfam PF03358 NADPH-dependent FMN reductase 1 155 1.4E-20 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CU254_RS15865 612ea6992d31a99e1a4fdf562e2f97c7 199 SUPERFAMILY SSF52218 1 191 2.42E-24 T 28-03-2018 IPR029039 Flavoprotein-like domain CU254_RS09670 10d58ceaa53e3432b8da0ade2353b102 301 Gene3D G3DSA:3.40.190.10 56 169 2.2E-27 T 28-03-2018 CU254_RS09670 10d58ceaa53e3432b8da0ade2353b102 301 SUPERFAMILY SSF53850 1 21 9.14E-60 T 28-03-2018 CU254_RS09670 10d58ceaa53e3432b8da0ade2353b102 301 SUPERFAMILY SSF53850 55 283 9.14E-60 T 28-03-2018 CU254_RS09670 10d58ceaa53e3432b8da0ade2353b102 301 SMART SM00062 65 289 1.5E-62 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CU254_RS09670 10d58ceaa53e3432b8da0ade2353b102 301 Gene3D G3DSA:3.40.190.10 170 251 5.2E-24 T 28-03-2018 CU254_RS09670 10d58ceaa53e3432b8da0ade2353b102 301 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 66 283 2.1E-51 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CU254_RS29560 45984f54c1e259abbaa95a73ffd4d585 355 Pfam PF03576 Peptidase family S58 19 344 3.6E-107 T 28-03-2018 IPR005321 Peptidase S58, DmpA CU254_RS29560 45984f54c1e259abbaa95a73ffd4d585 355 Gene3D G3DSA:3.60.70.12 2 354 1.7E-108 T 28-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CU254_RS29560 45984f54c1e259abbaa95a73ffd4d585 355 SUPERFAMILY SSF56266 2 350 1.73E-99 T 28-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CU254_RS14845 937ef79742c7459b6c8d624536276215 251 Gene3D G3DSA:3.90.320.10 13 145 0.3 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 CU254_RS34335 c04972ec22163e33568d7a520a877d75 284 SUPERFAMILY SSF51735 2 270 1.18E-48 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS34335 c04972ec22163e33568d7a520a877d75 284 Gene3D G3DSA:3.40.50.720 1 138 2.9E-19 T 28-03-2018 CU254_RS34335 c04972ec22163e33568d7a520a877d75 284 Pfam PF05368 NmrA-like family 2 218 3.4E-20 T 28-03-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 CU254_RS34335 c04972ec22163e33568d7a520a877d75 284 Gene3D G3DSA:3.40.50.720 139 262 7.3E-9 T 28-03-2018 CU254_RS28065 1a50ba36a9adfaa6310ccdeb20ae8563 258 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 132 152 - T 28-03-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site CU254_RS28065 1a50ba36a9adfaa6310ccdeb20ae8563 258 SUPERFAMILY SSF56317 10 252 4.97E-65 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CU254_RS28065 1a50ba36a9adfaa6310ccdeb20ae8563 258 Gene3D G3DSA:3.60.110.10 5 258 3.5E-67 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CU254_RS28065 1a50ba36a9adfaa6310ccdeb20ae8563 258 Pfam PF00795 Carbon-nitrogen hydrolase 12 235 6.3E-42 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CU254_RS14635 ccab62653f3c5991e9f403b15665edea 122 Gene3D G3DSA:3.40.190.10 1 122 1.1E-6 T 28-03-2018 CU254_RS01340 cd0b3cf9f2e3c721154e2dd4630ab208 136 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 35 135 1.2E-30 T 28-03-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS01340 cd0b3cf9f2e3c721154e2dd4630ab208 136 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 16 136 16.969 T 28-03-2018 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 CU254_RS21875 8b57b2885b39693a4661a23421a4a8c5 516 SUPERFAMILY SSF53067 266 443 2.2E-20 T 28-03-2018 CU254_RS21875 8b57b2885b39693a4661a23421a4a8c5 516 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 2 170 1.6E-36 T 28-03-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403 CU254_RS21875 8b57b2885b39693a4661a23421a4a8c5 516 SUPERFAMILY SSF53067 2 70 8.17E-8 T 28-03-2018 CU254_RS21875 8b57b2885b39693a4661a23421a4a8c5 516 Pfam PF01968 Hydantoinase/oxoprolinase 191 394 2.0E-32 T 28-03-2018 IPR002821 Hydantoinase/oxoprolinase GO:0016787 Reactome: R-HSA-174403 CU254_RS21875 8b57b2885b39693a4661a23421a4a8c5 516 Gene3D G3DSA:3.30.420.40 265 421 2.8E-8 T 28-03-2018 CU254_RS21875 8b57b2885b39693a4661a23421a4a8c5 516 Gene3D G3DSA:3.30.420.40 1 169 2.1E-9 T 28-03-2018 CU254_RS26690 268eace8f0664702ecb0baea07c4f650 203 SUPERFAMILY SSF53335 33 193 3.22E-31 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS26690 268eace8f0664702ecb0baea07c4f650 203 Pfam PF08241 Methyltransferase domain 62 153 1.2E-17 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CU254_RS26690 268eace8f0664702ecb0baea07c4f650 203 Gene3D G3DSA:3.40.50.150 43 202 2.8E-29 T 28-03-2018 CU254_RS30595 06b2609b4bf28fdde3d09797abdb117e 162 Gene3D G3DSA:3.40.140.10 4 162 6.6E-39 T 28-03-2018 CU254_RS30595 06b2609b4bf28fdde3d09797abdb117e 162 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 12 107 3.3E-22 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CU254_RS30595 06b2609b4bf28fdde3d09797abdb117e 162 SUPERFAMILY SSF53927 10 157 7.62E-43 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CU254_RS36645 c55eb09df736b182f6b8410bfd2eff33 112 SUPERFAMILY SSF51182 22 104 6.17E-18 T 28-03-2018 IPR011051 RmlC-like cupin domain CU254_RS36645 c55eb09df736b182f6b8410bfd2eff33 112 Gene3D G3DSA:2.60.120.10 2 107 1.3E-14 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS36645 c55eb09df736b182f6b8410bfd2eff33 112 Pfam PF07883 Cupin domain 38 95 1.8E-11 T 28-03-2018 IPR013096 Cupin 2, conserved barrel CU254_RS27500 aa9cb99ee70c504a839d3bd897955462 206 SUPERFAMILY SSF52833 6 177 3.52E-19 T 28-03-2018 IPR012336 Thioredoxin-like fold CU254_RS27500 aa9cb99ee70c504a839d3bd897955462 206 Pfam PF01323 DSBA-like thioredoxin domain 9 164 2.5E-9 T 28-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 CU254_RS27500 aa9cb99ee70c504a839d3bd897955462 206 Gene3D G3DSA:3.40.30.10 1 185 2.1E-22 T 28-03-2018 CU254_RS32535 6458cb816f6cff44d0ab94b855653a45 243 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 207 239 1.5E-4 T 28-03-2018 CU254_RS23625 b7a60acfe13117e7169ef5ba16114bc0 83 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 31 80 1.6E-5 T 28-03-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 CU254_RS18645 2ac53190e0010852e6b6807d3774d23b 405 Pfam PF01594 AI-2E family transporter 35 356 4.7E-64 T 28-03-2018 IPR002549 Transmembrane protein TqsA-like CU254_RS31805 796b4e045d75eaca6dbf3cdc8c7940f8 302 Pfam PF01061 ABC-2 type transporter 30 262 6.1E-20 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CU254_RS09370 beaf5177e62b333f5a7fa3e6b38d4fe7 343 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 11 274 1.2E-46 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CU254_RS09370 beaf5177e62b333f5a7fa3e6b38d4fe7 343 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 12 282 15.654 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CU254_RS09370 beaf5177e62b333f5a7fa3e6b38d4fe7 343 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 17 276 1.8E-67 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CU254_RS09370 beaf5177e62b333f5a7fa3e6b38d4fe7 343 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 144 156 - T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CU254_RS35985 c95ad27941f87df7eb3ee956b5f79d47 665 Gene3D G3DSA:3.40.50.300 1 287 1.8E-4 T 28-03-2018 CU254_RS42475 dc98d255ec575cec187720ebf9b5345c 158 Gene3D G3DSA:3.90.79.10 12 154 1.9E-25 T 28-03-2018 CU254_RS42475 dc98d255ec575cec187720ebf9b5345c 158 Pfam PF00293 NUDIX domain 19 144 5.2E-14 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CU254_RS42475 dc98d255ec575cec187720ebf9b5345c 158 SUPERFAMILY SSF55811 9 146 8.53E-22 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CU254_RS38330 b089ac9c2b0186f54a471c6e3ad12ba5 258 Pfam PF13349 Putative adhesin 110 256 1.4E-12 T 28-03-2018 IPR025164 Putative adhesin CU254_RS38330 b089ac9c2b0186f54a471c6e3ad12ba5 258 Gene3D G3DSA:2.60.120.380 42 247 6.1E-4 T 28-03-2018 CU254_RS36580 aab1cdf1ce523fee3f8005d58001ac81 358 Pfam PF03824 High-affinity nickel-transport protein 50 338 2.8E-87 T 28-03-2018 IPR011541 Nickel/cobalt transporter, high-affinity GO:0015099|GO:0016021|GO:0035444|GO:0046872 CU254_RS36580 aab1cdf1ce523fee3f8005d58001ac81 358 TIGRFAM TIGR00802 nico: transition metal uptake transporter, Ni2+-Co2+ transporter (NiCoT) family 53 334 1.8E-113 T 28-03-2018 IPR004688 Transition metal uptake transporter nickel/cobalt GO:0015099|GO:0016021|GO:0035444|GO:0046872 CU254_RS39655 de5595f42072e0d5c551aa6357e84e1c 286 SUPERFAMILY SSF51621 3 232 8.28E-70 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CU254_RS39655 de5595f42072e0d5c551aa6357e84e1c 286 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 8 220 7.4E-47 T 28-03-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 CU254_RS39655 de5595f42072e0d5c551aa6357e84e1c 286 Gene3D G3DSA:3.20.20.360 1 259 1.7E-64 T 28-03-2018 CU254_RS39655 de5595f42072e0d5c551aa6357e84e1c 286 PIRSF PIRSF015582 1 286 2.6E-86 T 28-03-2018 IPR011206 Citrate lyase beta subunit-like CU254_RS33475 e970f45ad99f0807adb80a7555d42da5 227 Gene3D G3DSA:3.40.470.10 2 226 8.1E-52 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CU254_RS33475 e970f45ad99f0807adb80a7555d42da5 227 SUPERFAMILY SSF52141 14 220 5.23E-40 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CU254_RS33475 e970f45ad99f0807adb80a7555d42da5 227 SMART SM00986 45 217 9.6E-24 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CU254_RS33475 e970f45ad99f0807adb80a7555d42da5 227 Pfam PF03167 Uracil DNA glycosylase superfamily 45 217 7.1E-27 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CU254_RS33475 e970f45ad99f0807adb80a7555d42da5 227 SMART SM00987 45 217 9.6E-24 T 28-03-2018 CU254_RS26360 1e8f2dbe9f25de19d7e158ad65556845 205 Pfam PF04203 Sortase family 103 201 2.4E-11 T 28-03-2018 IPR005754 Sortase family CU254_RS26360 1e8f2dbe9f25de19d7e158ad65556845 205 SUPERFAMILY SSF63817 53 200 1.22E-12 T 28-03-2018 IPR023365 Sortase domain CU254_RS26360 1e8f2dbe9f25de19d7e158ad65556845 205 Gene3D G3DSA:2.40.260.10 36 205 4.2E-18 T 28-03-2018 IPR023365 Sortase domain CU254_RS24135 45a6a915694b7ac9cce3a43dc6f821cd 367 Gene3D G3DSA:3.30.390.10 1 134 1.7E-40 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CU254_RS24135 45a6a915694b7ac9cce3a43dc6f821cd 367 Pfam PF13378 Enolase C-terminal domain-like 143 357 4.1E-38 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CU254_RS24135 45a6a915694b7ac9cce3a43dc6f821cd 367 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 14 123 5.6E-19 T 28-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CU254_RS24135 45a6a915694b7ac9cce3a43dc6f821cd 367 SUPERFAMILY SSF51604 122 363 5.5E-56 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CU254_RS24135 45a6a915694b7ac9cce3a43dc6f821cd 367 SMART SM00922 140 238 9.8E-25 T 28-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CU254_RS24135 45a6a915694b7ac9cce3a43dc6f821cd 367 Gene3D G3DSA:3.20.20.120 135 352 1.8E-46 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CU254_RS24135 45a6a915694b7ac9cce3a43dc6f821cd 367 SUPERFAMILY SSF54826 1 124 7.55E-35 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CU254_RS20660 06a62fcf179d1261ac4e3ce9252cdf76 272 Gene3D G3DSA:2.40.400.10 1 244 4.4E-29 T 28-03-2018 IPR023375 Acetoacetate decarboxylase beta barrel domain KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 CU254_RS20660 06a62fcf179d1261ac4e3ce9252cdf76 272 Pfam PF06314 Acetoacetate decarboxylase (ADC) 10 250 2.6E-40 T 28-03-2018 IPR010451 Acetoacetate decarboxylase GO:0016829 KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 CU254_RS20660 06a62fcf179d1261ac4e3ce9252cdf76 272 SUPERFAMILY SSF160104 4 249 7.06E-46 T 28-03-2018 IPR023375 Acetoacetate decarboxylase beta barrel domain KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 CU254_RS32500 518ea9d4611c22212b2f9b8c7adcfb87 330 Gene3D G3DSA:1.10.260.40 24 104 2.9E-5 T 28-03-2018 CU254_RS27635 db2ecfbf91eb47fe998b108a690295c7 109 Pfam PF05360 yiaA/B two helix domain 14 66 2.9E-16 T 28-03-2018 IPR008024 YiaAB two helix CU254_RS07000 e09e98dc7f2cf3a023d5d0c30420d379 294 Gene3D G3DSA:1.10.3720.10 44 271 4.2E-28 T 28-03-2018 CU254_RS07000 e09e98dc7f2cf3a023d5d0c30420d379 294 SUPERFAMILY SSF161098 94 274 2.35E-37 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS07000 e09e98dc7f2cf3a023d5d0c30420d379 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 269 3.4E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS01770 9a937c4846fab3f5e7d7f2f4dc552f47 278 Pfam PF02405 Permease MlaE 61 263 3.0E-59 T 28-03-2018 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 CU254_RS17680 f1fea812b10cb42e58c846a7580fa8f0 282 PIRSF PIRSF000707 4 247 1.7E-10 T 28-03-2018 IPR016259 Hygromycin-B kinase KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 CU254_RS17680 f1fea812b10cb42e58c846a7580fa8f0 282 Pfam PF01636 Phosphotransferase enzyme family 31 245 1.1E-28 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CU254_RS17680 f1fea812b10cb42e58c846a7580fa8f0 282 Gene3D G3DSA:3.30.200.20 3 96 3.7E-5 T 28-03-2018 CU254_RS17680 f1fea812b10cb42e58c846a7580fa8f0 282 Gene3D G3DSA:3.90.1200.10 97 278 6.8E-17 T 28-03-2018 CU254_RS17680 f1fea812b10cb42e58c846a7580fa8f0 282 SUPERFAMILY SSF56112 16 255 1.4E-43 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS31210 b3f7b9adc44900197575c6be0d46585a 208 PIRSF PIRSF006324 2 208 8.0E-58 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CU254_RS31210 b3f7b9adc44900197575c6be0d46585a 208 Pfam PF01810 LysE type translocator 16 207 9.1E-40 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CU254_RS36795 47d0147d421dd9fb7057588591c48017 274 Gene3D G3DSA:3.90.79.10 26 245 1.1E-30 T 28-03-2018 CU254_RS36795 47d0147d421dd9fb7057588591c48017 274 SUPERFAMILY SSF55811 107 118 2.62E-18 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CU254_RS36795 47d0147d421dd9fb7057588591c48017 274 SUPERFAMILY SSF55811 160 231 2.62E-18 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CU254_RS36795 47d0147d421dd9fb7057588591c48017 274 SUPERFAMILY SSF55811 15 79 2.62E-18 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CU254_RS37985 82d06b7b848bba6dcd890cb55ac4429f 136 Pfam PF11349 Protein of unknown function (DUF3151) 7 131 4.4E-60 T 28-03-2018 IPR014487 Protein of unknown function DUF3151 CU254_RS37985 82d06b7b848bba6dcd890cb55ac4429f 136 Gene3D G3DSA:1.25.40.10 16 132 4.7E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS37985 82d06b7b848bba6dcd890cb55ac4429f 136 PIRSF PIRSF017349 1 135 2.1E-60 T 28-03-2018 IPR014487 Protein of unknown function DUF3151 CU254_RS15155 c931a9656736276506f9fdccbc3b693b 221 Pfam PF11575 FhuF 2Fe-2S C-terminal domain 197 220 5.8E-6 T 28-03-2018 IPR024726 Ferric iron reductase, C-terminal GO:0051537 CU254_RS27085 ce7dbac5ab369a8db0358ad9f8a1dba1 76 Pfam PF16827 zinc-finger 2 64 4.8E-22 T 28-03-2018 IPR031795 Putative zinc-finger containing protein CU254_RS37740 8edc6d37252be4661fc777d110ce89c6 278 Pfam PF01734 Patatin-like phospholipase 5 198 2.8E-17 T 28-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 CU254_RS37740 8edc6d37252be4661fc777d110ce89c6 278 SUPERFAMILY SSF52151 135 211 2.04E-29 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CU254_RS37740 8edc6d37252be4661fc777d110ce89c6 278 SUPERFAMILY SSF52151 2 75 2.04E-29 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CU254_RS37740 8edc6d37252be4661fc777d110ce89c6 278 Gene3D G3DSA:3.40.1090.10 1 216 1.4E-30 T 28-03-2018 CU254_RS10750 f0a39f9a3846aa1b94beecda464dcf34 477 Pfam PF02653 Branched-chain amino acid transport system / permease component 160 461 2.7E-30 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CU254_RS10750 f0a39f9a3846aa1b94beecda464dcf34 477 Gene3D G3DSA:1.10.3470.10 35 471 2.7E-17 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CU254_RS37960 6edd8a36d93e9703e03fc0fe94998d53 625 Pfam PF13454 FAD-NAD(P)-binding 10 185 5.4E-41 T 28-03-2018 CU254_RS37960 6edd8a36d93e9703e03fc0fe94998d53 625 Gene3D G3DSA:3.50.50.60 5 623 7.8E-21 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS37960 6edd8a36d93e9703e03fc0fe94998d53 625 SUPERFAMILY SSF51905 119 245 2.42E-10 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS37960 6edd8a36d93e9703e03fc0fe94998d53 625 SUPERFAMILY SSF51905 7 55 2.42E-10 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS21290 f7d94e9c66c1be628497da62a132dd1c 254 Pfam PF01925 Sulfite exporter TauE/SafE 12 246 2.0E-31 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CU254_RS16650 0ba9a89567f8f04c1050cda7cc815da8 347 Pfam PF13515 Fusaric acid resistance protein-like 197 329 1.4E-21 T 28-03-2018 CU254_RS11815 479489f7167b902a547d292222fc187b 256 Gene3D G3DSA:3.40.50.300 1 252 6.4E-41 T 28-03-2018 CU254_RS11815 479489f7167b902a547d292222fc187b 256 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 4 246 1.3E-104 T 28-03-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524|GO:0006810 CU254_RS11815 479489f7167b902a547d292222fc187b 256 SUPERFAMILY SSF52540 4 233 2.72E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS11815 479489f7167b902a547d292222fc187b 256 Pfam PF00005 ABC transporter 23 174 5.7E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS11815 479489f7167b902a547d292222fc187b 256 SMART SM00382 32 226 5.6E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS20760 55aa4f8f8bd33f8a457f7399e649913c 389 Pfam PF06742 Protein of unknown function (DUF1214) 80 150 0.006 T 28-03-2018 IPR010621 Domain of unknown function DUF1214 CU254_RS20760 55aa4f8f8bd33f8a457f7399e649913c 389 Gene3D G3DSA:2.60.120.600 233 355 5.1E-10 T 28-03-2018 IPR010621 Domain of unknown function DUF1214 CU254_RS20760 55aa4f8f8bd33f8a457f7399e649913c 389 Gene3D G3DSA:2.60.120.600 39 197 1.5E-9 T 28-03-2018 IPR010621 Domain of unknown function DUF1214 CU254_RS41695 517597b1cbcc6fb110a291e5d3712080 351 Gene3D G3DSA:3.90.1720.10 210 349 5.4E-29 T 28-03-2018 CU254_RS41695 517597b1cbcc6fb110a291e5d3712080 351 SUPERFAMILY SSF54001 214 348 1.37E-29 T 28-03-2018 CU254_RS41695 517597b1cbcc6fb110a291e5d3712080 351 Pfam PF01464 Transglycosylase SLT domain 63 181 1.1E-15 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 CU254_RS41695 517597b1cbcc6fb110a291e5d3712080 351 Gene3D G3DSA:1.10.530.10 36 195 2.8E-38 T 28-03-2018 CU254_RS41695 517597b1cbcc6fb110a291e5d3712080 351 SUPERFAMILY SSF53955 51 190 1.29E-33 T 28-03-2018 IPR023346 Lysozyme-like domain CU254_RS41695 517597b1cbcc6fb110a291e5d3712080 351 Pfam PF00877 NlpC/P60 family 226 345 2.0E-22 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CU254_RS09495 c4bfd45075af3b2000f0b0bef56c7d07 174 Pfam PF04073 Aminoacyl-tRNA editing domain 34 156 3.1E-26 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CU254_RS09495 c4bfd45075af3b2000f0b0bef56c7d07 174 SUPERFAMILY SSF55826 13 165 3.4E-29 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CU254_RS09495 c4bfd45075af3b2000f0b0bef56c7d07 174 Gene3D G3DSA:3.90.960.10 1 166 7.2E-31 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CU254_RS26740 8e3f70ae627fbbb5e35124e7264384e6 272 Pfam PF12294 Protein of unknown function (DUF3626) 147 257 2.3E-23 T 28-03-2018 IPR022074 Protein of unknown function DUF3626 CU254_RS26740 8e3f70ae627fbbb5e35124e7264384e6 272 Pfam PF12294 Protein of unknown function (DUF3626) 25 151 1.7E-38 T 28-03-2018 IPR022074 Protein of unknown function DUF3626 CU254_RS34860 38a18d78f6090ff9be1aadb88eb8cf41 301 SUPERFAMILY SSF74650 7 299 5.27E-53 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CU254_RS34860 38a18d78f6090ff9be1aadb88eb8cf41 301 Gene3D G3DSA:2.70.98.10 2 301 8.6E-63 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 CU254_RS34860 38a18d78f6090ff9be1aadb88eb8cf41 301 Pfam PF01263 Aldose 1-epimerase 8 295 4.1E-37 T 28-03-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 CU254_RS01095 eb2dea5609f5c9ae5cb4c792b58a4059 342 Gene3D G3DSA:3.40.1130.10 94 340 2.8E-24 T 28-03-2018 CU254_RS01095 eb2dea5609f5c9ae5cb4c792b58a4059 342 SMART SM00563 129 247 9.3E-14 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CU254_RS01095 eb2dea5609f5c9ae5cb4c792b58a4059 342 SUPERFAMILY SSF69593 82 330 8.89E-29 T 28-03-2018 CU254_RS01095 eb2dea5609f5c9ae5cb4c792b58a4059 342 PIRSF PIRSF016753 36 342 4.8E-91 T 28-03-2018 IPR016676 Phospholipid/glycerol acyltransferase, predicted CU254_RS01095 eb2dea5609f5c9ae5cb4c792b58a4059 342 Pfam PF01553 Acyltransferase 119 244 1.9E-14 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CU254_RS02300 f0d65851783f7fa92eef64950265cce3 248 Pfam PF14011 EspG family 17 241 4.7E-39 T 28-03-2018 IPR025734 EspG family CU254_RS00905 5b63f7f857725be4957830472c6b3e70 181 Gene3D G3DSA:3.90.960.10 17 178 4.1E-27 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CU254_RS00905 5b63f7f857725be4957830472c6b3e70 181 Pfam PF04073 Aminoacyl-tRNA editing domain 46 168 6.8E-19 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CU254_RS00905 5b63f7f857725be4957830472c6b3e70 181 SUPERFAMILY SSF55826 42 177 1.7E-24 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CU254_RS41225 8f9d472dfae4c18bba08576661afc8b7 336 Pfam PF04672 S-adenosyl methyltransferase 63 336 3.0E-71 T 28-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CU254_RS41225 8f9d472dfae4c18bba08576661afc8b7 336 SUPERFAMILY SSF53335 74 316 1.14E-28 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS41225 8f9d472dfae4c18bba08576661afc8b7 336 Gene3D G3DSA:3.40.50.150 50 336 6.6E-42 T 28-03-2018 CU254_RS08755 3c63c793f1a01a531b0c3a5d54575ee3 366 Pfam PF13354 Beta-lactamase enzyme family 54 273 4.0E-14 T 28-03-2018 CU254_RS08755 3c63c793f1a01a531b0c3a5d54575ee3 366 Gene3D G3DSA:3.40.710.10 12 337 1.9E-12 T 28-03-2018 CU254_RS08755 3c63c793f1a01a531b0c3a5d54575ee3 366 SUPERFAMILY SSF56601 54 199 1.83E-14 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CU254_RS08755 3c63c793f1a01a531b0c3a5d54575ee3 366 SUPERFAMILY SSF56601 252 334 1.83E-14 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CU254_RS09655 c2d63908b96ee9efee7c02cedc6f8851 118 SUPERFAMILY SSF54593 5 109 1.51E-16 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS09655 c2d63908b96ee9efee7c02cedc6f8851 118 Gene3D G3DSA:3.10.180.10 4 118 1.2E-13 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS28145 38840902f14303489660c776882e8a9e 218 SMART SM00855 3 162 3.0E-8 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CU254_RS28145 38840902f14303489660c776882e8a9e 218 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 203 2.0E-21 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CU254_RS28145 38840902f14303489660c776882e8a9e 218 Gene3D G3DSA:3.40.50.1240 2 213 3.2E-30 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CU254_RS28145 38840902f14303489660c776882e8a9e 218 SUPERFAMILY SSF53254 1 210 1.83E-33 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CU254_RS17230 d2d1be6e527e209a1546572af7ae08bf 141 SUPERFAMILY SSF55331 2 58 8.63E-6 T 28-03-2018 IPR014347 Tautomerase/MIF superfamily CU254_RS17230 d2d1be6e527e209a1546572af7ae08bf 141 Gene3D G3DSA:3.30.429.10 1 141 1.4E-37 T 28-03-2018 CU254_RS17230 d2d1be6e527e209a1546572af7ae08bf 141 Pfam PF14832 Putative oxalocrotonate tautomerase enzyme 1 136 3.4E-44 T 28-03-2018 IPR028116 Putative oxalocrotonate tautomerase CU254_RS01130 6b2efd4cf21f1ae39f8fced51a6bc11e 71 Gene3D G3DSA:3.40.30.10 1 71 5.3E-11 T 28-03-2018 CU254_RS01130 6b2efd4cf21f1ae39f8fced51a6bc11e 71 Pfam PF05768 Glutaredoxin-like domain (DUF836) 1 70 1.2E-16 T 28-03-2018 IPR008554 Glutaredoxin-like CU254_RS01130 6b2efd4cf21f1ae39f8fced51a6bc11e 71 SUPERFAMILY SSF52833 2 71 6.46E-17 T 28-03-2018 IPR012336 Thioredoxin-like fold CU254_RS32375 5687d31453730e30585b477d3967058c 476 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 179 194 - T 28-03-2018 IPR019826 Carboxylesterase type B, active site CU254_RS32375 5687d31453730e30585b477d3967058c 476 Gene3D G3DSA:3.40.50.1820 2 476 1.6E-107 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS32375 5687d31453730e30585b477d3967058c 476 SUPERFAMILY SSF53474 7 468 1.45E-92 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS32375 5687d31453730e30585b477d3967058c 476 Pfam PF00135 Carboxylesterase family 7 471 5.3E-80 T 28-03-2018 IPR002018 Carboxylesterase, type B CU254_RS21130 a6e1094707ceae0350275512b037fb00 456 Gene3D G3DSA:3.20.20.190 18 245 1.6E-15 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CU254_RS21130 a6e1094707ceae0350275512b037fb00 456 SUPERFAMILY SSF51695 25 179 1.12E-15 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CU254_RS05455 1e03a14b49d7e194a399aa10e6e2517b 197 SUPERFAMILY SSF48498 62 171 1.5E-15 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS05455 1e03a14b49d7e194a399aa10e6e2517b 197 SUPERFAMILY SSF46689 2 63 2.15E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS05455 1e03a14b49d7e194a399aa10e6e2517b 197 Gene3D G3DSA:1.10.357.10 1 175 2.8E-23 T 28-03-2018 CU254_RS05455 1e03a14b49d7e194a399aa10e6e2517b 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 2 40 8.5E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS12915 8adbb26affda64fd96d0fca3caa825f9 108 Gene3D G3DSA:3.30.390.50 1 108 3.9E-21 T 28-03-2018 CU254_RS12915 8adbb26affda64fd96d0fca3caa825f9 108 SUPERFAMILY SSF55447 3 103 2.75E-12 T 28-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal CU254_RS12915 8adbb26affda64fd96d0fca3caa825f9 108 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 3 98 5.7E-6 T 28-03-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal CU254_RS18920 b4b2ea9a65bf34b0cbd2e6114a1ea907 306 Gene3D G3DSA:3.40.50.720 3 126 4.2E-9 T 28-03-2018 CU254_RS18920 b4b2ea9a65bf34b0cbd2e6114a1ea907 306 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 212 9.2E-13 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CU254_RS18920 b4b2ea9a65bf34b0cbd2e6114a1ea907 306 SUPERFAMILY SSF51735 4 278 9.44E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS18920 b4b2ea9a65bf34b0cbd2e6114a1ea907 306 Gene3D G3DSA:3.90.25.10 156 305 6.0E-10 T 28-03-2018 CU254_RS21540 2cbe4c1fe21dfc2b56e733c2f1077bbd 147 Pfam PF07883 Cupin domain 47 110 1.4E-7 T 28-03-2018 IPR013096 Cupin 2, conserved barrel CU254_RS21540 2cbe4c1fe21dfc2b56e733c2f1077bbd 147 Gene3D G3DSA:2.60.120.10 2 139 2.1E-13 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS21540 2cbe4c1fe21dfc2b56e733c2f1077bbd 147 SUPERFAMILY SSF51182 27 126 3.57E-15 T 28-03-2018 IPR011051 RmlC-like cupin domain CU254_RS26410 95770a72938b2428e7a41a584a424f48 152 Pfam PF04505 Interferon-induced transmembrane protein 64 127 1.9E-13 T 28-03-2018 IPR007593 CD225/Dispanin family GO:0009607|GO:0016021 CU254_RS39785 e4f37e3b9bf15417dd9790decd977e04 551 TIGRFAM TIGR03491 TIGR03491: putative RecB family nuclease, TM0106 family 15 537 1.7E-58 T 28-03-2018 IPR019993 RecB family nuclease, TM0106, putative CU254_RS39785 e4f37e3b9bf15417dd9790decd977e04 551 Pfam PF13482 RNase_H superfamily 453 537 6.4E-11 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS25140 f719b7d8d4cf9ac2a8fbdc02b1684e5c 344 Pfam PF13593 SBF-like CPA transporter family (DUF4137) 22 330 4.3E-94 T 28-03-2018 IPR016833 Putative sodium bile acid cotransporter CU254_RS25140 f719b7d8d4cf9ac2a8fbdc02b1684e5c 344 PIRSF PIRSF026166 11 342 5.3E-129 T 28-03-2018 IPR016833 Putative sodium bile acid cotransporter CU254_RS24010 f8a0e6c65a7fdf75aaa946d7ef182806 203 SUPERFAMILY SSF46689 18 79 5.99E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS24010 f8a0e6c65a7fdf75aaa946d7ef182806 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 71 1.3E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS24010 f8a0e6c65a7fdf75aaa946d7ef182806 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 3.7E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS24010 f8a0e6c65a7fdf75aaa946d7ef182806 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 3.7E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS24010 f8a0e6c65a7fdf75aaa946d7ef182806 203 Gene3D G3DSA:1.10.10.60 59 124 9.5E-11 T 28-03-2018 CU254_RS24010 f8a0e6c65a7fdf75aaa946d7ef182806 203 Gene3D G3DSA:1.10.10.60 2 58 1.3E-16 T 28-03-2018 CU254_RS18240 58ac9884480fe2cd611d4913f18e3462 265 Gene3D G3DSA:3.60.20.10 8 239 2.2E-42 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CU254_RS18240 58ac9884480fe2cd611d4913f18e3462 265 Pfam PF00227 Proteasome subunit 25 201 4.5E-28 T 28-03-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-446652|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8941858|Reactome: R-HSA-8951664|Reactome: R-HSA-983168 CU254_RS18240 58ac9884480fe2cd611d4913f18e3462 265 Hamap MF_00289_B Proteasome subunit alpha [prcA]. 1 236 48.184 T 28-03-2018 IPR022296 Proteasome, alpha subunit, bacterial GO:0004298|GO:0019773|GO:0051603 CU254_RS18240 58ac9884480fe2cd611d4913f18e3462 265 SUPERFAMILY SSF56235 10 232 8.99E-41 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CU254_RS18240 58ac9884480fe2cd611d4913f18e3462 265 TIGRFAM TIGR03691 20S_bact_alpha: proteasome, alpha subunit 2 232 4.3E-106 T 28-03-2018 IPR022296 Proteasome, alpha subunit, bacterial GO:0004298|GO:0019773|GO:0051603 CU254_RS06885 a321c43afef9ecd9f32a1d688080631d 226 Gene3D G3DSA:1.25.10.10 116 193 2.6E-4 T 28-03-2018 IPR011989 Armadillo-like helical CU254_RS06885 a321c43afef9ecd9f32a1d688080631d 226 Gene3D G3DSA:1.25.10.10 3 115 6.9E-14 T 28-03-2018 IPR011989 Armadillo-like helical CU254_RS06885 a321c43afef9ecd9f32a1d688080631d 226 Pfam PF13646 HEAT repeats 43 124 2.2E-7 T 28-03-2018 CU254_RS06885 a321c43afef9ecd9f32a1d688080631d 226 SUPERFAMILY SSF48371 11 191 4.61E-15 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 CU254_RS25430 2fa9febecc6dfa65e23427b575eb3642 60 Pfam PF13556 PucR C-terminal helix-turn-helix domain 1 53 1.2E-9 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CU254_RS37455 9c71f64a59d26d81ce84d772fd437302 246 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 223 1.0E-28 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS37455 9c71f64a59d26d81ce84d772fd437302 246 SMART SM00862 149 223 3.5E-28 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CU254_RS37455 9c71f64a59d26d81ce84d772fd437302 246 SUPERFAMILY SSF46894 127 224 5.39E-30 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CU254_RS37455 9c71f64a59d26d81ce84d772fd437302 246 Gene3D G3DSA:1.10.10.10 114 230 1.9E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS15160 165875e5a6cdc294f3f1b216133ff0de 194 Pfam PF12079 Protein of unknown function (DUF3558) 27 186 4.5E-20 T 28-03-2018 IPR024520 Protein of unknown function DUF3558 CU254_RS06420 19f2ff767afd5557b4ef75ca5c2e5bc8 347 Gene3D G3DSA:1.10.3470.10 32 340 6.0E-21 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CU254_RS06420 19f2ff767afd5557b4ef75ca5c2e5bc8 347 Pfam PF02653 Branched-chain amino acid transport system / permease component 59 334 1.3E-38 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CU254_RS39080 966986eed4772f434ad57fb5e3ff131c 386 Pfam PF13449 Esterase-like activity of phytase 50 368 3.9E-76 T 28-03-2018 IPR027372 Phytase-like domain CU254_RS32920 1bf6a7854c51e5526cd12121d59b1475 510 Pfam PF14011 EspG family 278 501 7.0E-31 T 28-03-2018 IPR025734 EspG family CU254_RS32215 e0a50248cff4fe1e484ebf699f1d5757 127 Gene3D G3DSA:1.10.1900.10 31 116 1.5E-24 T 28-03-2018 CU254_RS32215 e0a50248cff4fe1e484ebf699f1d5757 127 Pfam PF06304 Protein of unknown function (DUF1048) 20 119 1.2E-26 T 28-03-2018 IPR008316 Uncharacterised conserved protein UCP029876 CU254_RS32215 e0a50248cff4fe1e484ebf699f1d5757 127 SUPERFAMILY SSF158560 11 118 3.27E-30 T 28-03-2018 CU254_RS10415 3a16ffdd3ea4d412a1bf8d202272c225 178 Pfam PF17197 Domain of unknown function (DUF5134) 30 176 1.1E-27 T 28-03-2018 IPR033458 Protein of unknown function DUF5134 CU254_RS10415 3a16ffdd3ea4d412a1bf8d202272c225 178 SUPERFAMILY SSF53213 43 134 9.94E-5 T 28-03-2018 CU254_RS15405 eda8f96c1af87b1117ee91ef67d72d3c 92 Pfam PF11239 Protein of unknown function (DUF3040) 1 79 2.3E-15 T 28-03-2018 IPR021401 Protein of unknown function DUF3040 CU254_RS34945 b78cfb3b8e0b9b33fb2a7c5eecfde3c8 242 Pfam PF01774 UreD urease accessory protein 42 170 9.1E-21 T 28-03-2018 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 CU254_RS34945 b78cfb3b8e0b9b33fb2a7c5eecfde3c8 242 Hamap MF_01384 Urease accessory protein UreD [ureD]. 3 239 15.194 T 28-03-2018 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 CU254_RS19550 7b75f6375c5bae088ba7682d59bb577f 695 Pfam PF13515 Fusaric acid resistance protein-like 378 504 1.2E-13 T 28-03-2018 CU254_RS26390 caf700609718f6ce0d8e423d3af69e5c 349 Pfam PF03773 Predicted permease 64 341 7.4E-47 T 28-03-2018 IPR005524 Predicted permease DUF318 CU254_RS06700 e26566b124977d762d7a2f65f2864774 257 SUPERFAMILY SSF53335 29 196 4.85E-34 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS06700 e26566b124977d762d7a2f65f2864774 257 Gene3D G3DSA:3.40.50.150 14 212 8.9E-31 T 28-03-2018 CU254_RS06700 e26566b124977d762d7a2f65f2864774 257 Pfam PF08241 Methyltransferase domain 49 140 6.0E-19 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CU254_RS15870 a3f88c88f7eb22822485410c4a500306 349 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 236 8.8E-21 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CU254_RS15870 a3f88c88f7eb22822485410c4a500306 349 SUPERFAMILY SSF51735 2 321 1.21E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS15870 a3f88c88f7eb22822485410c4a500306 349 Gene3D G3DSA:3.40.50.720 1 325 8.4E-43 T 28-03-2018 CU254_RS36710 db598a68bd3e55c364548f9b466ae5c7 363 SUPERFAMILY SSF51395 5 358 2.93E-93 T 28-03-2018 CU254_RS36710 db598a68bd3e55c364548f9b466ae5c7 363 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 5 334 3.6E-60 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CU254_RS36710 db598a68bd3e55c364548f9b466ae5c7 363 Gene3D G3DSA:3.20.20.70 1 363 2.5E-98 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS35715 9dbb7005dddba60c426f00e98d506178 242 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 84 238 1.3E-5 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CU254_RS35715 9dbb7005dddba60c426f00e98d506178 242 Gene3D G3DSA:3.90.850.10 2 241 5.4E-38 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CU254_RS35715 9dbb7005dddba60c426f00e98d506178 242 SUPERFAMILY SSF56529 9 240 1.96E-63 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CU254_RS06155 b856ba51f2c9cd6125b67e01f1c8b098 329 Gene3D G3DSA:3.40.50.620 151 293 7.1E-35 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS06155 b856ba51f2c9cd6125b67e01f1c8b098 329 Pfam PF02698 DUF218 domain 160 301 1.5E-30 T 28-03-2018 IPR003848 Domain of unknown function DUF218 CU254_RS33630 fbe1be88ac6cf8591e5da5c26e8af550 136 TIGRFAM TIGR04023 PPOX_MSMEG_5819: PPOX class F420-dependent enzyme, MSMEG_5819/OxyR family 2 119 2.8E-42 T 28-03-2018 IPR024031 PPOX class F420-dependent enzyme, MSMEG_5819/OxyR family CU254_RS33630 fbe1be88ac6cf8591e5da5c26e8af550 136 Gene3D G3DSA:2.30.110.10 1 115 6.0E-20 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS33630 fbe1be88ac6cf8591e5da5c26e8af550 136 SUPERFAMILY SSF50475 3 120 1.61E-20 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS33630 fbe1be88ac6cf8591e5da5c26e8af550 136 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 2 95 9.0E-15 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CU254_RS31100 4fc5e27d897b837c871e5ed4316331bc 67 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 49 8.0E-15 T 28-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain CU254_RS31100 4fc5e27d897b837c871e5ed4316331bc 67 Pfam PF09723 Zinc ribbon domain 1 40 6.8E-12 T 28-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain CU254_RS31100 4fc5e27d897b837c871e5ed4316331bc 67 SMART SM00834 1 42 1.4E-12 T 28-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain CU254_RS39020 443f3eb511efe3a0e15bb0bb3c982a4c 377 Gene3D G3DSA:3.30.565.10 163 372 1.4E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS39020 443f3eb511efe3a0e15bb0bb3c982a4c 377 SUPERFAMILY SSF55874 266 371 1.38E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS39020 443f3eb511efe3a0e15bb0bb3c982a4c 377 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 278 371 1.5E-5 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS22420 478e9dafcb76dd59278342733692a7a7 211 Hamap MF_00527 Putative 3-methyladenine DNA glycosylase. 5 196 31.618 T 28-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CU254_RS22420 478e9dafcb76dd59278342733692a7a7 211 TIGRFAM TIGR00567 3mg: DNA-3-methyladenine glycosylase 9 196 5.8E-54 T 28-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CU254_RS22420 478e9dafcb76dd59278342733692a7a7 211 Gene3D G3DSA:3.10.300.10 4 204 9.3E-67 T 28-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CU254_RS22420 478e9dafcb76dd59278342733692a7a7 211 SUPERFAMILY SSF50486 8 201 9.42E-58 T 28-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 CU254_RS22420 478e9dafcb76dd59278342733692a7a7 211 Pfam PF02245 Methylpurine-DNA glycosylase (MPG) 15 193 5.1E-62 T 28-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CU254_RS34155 9b4352aaf008aae41e0d9a4b1d9b693f 109 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 2 51 7.1E-20 T 28-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain CU254_RS34155 9b4352aaf008aae41e0d9a4b1d9b693f 109 Pfam PF09723 Zinc ribbon domain 2 40 4.9E-15 T 28-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain CU254_RS34155 9b4352aaf008aae41e0d9a4b1d9b693f 109 SMART SM00834 2 41 5.0E-14 T 28-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain CU254_RS40275 e21181d6ec946fa1aff3fbbc019563c8 350 Gene3D G3DSA:3.40.50.980 61 259 6.6E-4 T 28-03-2018 CU254_RS40275 e21181d6ec946fa1aff3fbbc019563c8 350 Pfam PF04443 Acyl-protein synthetase, LuxE 19 346 2.3E-46 T 28-03-2018 IPR007534 Acyl-protein synthetase, LuxE GO:0008218|GO:0047474 MetaCyc: PWY-7723 CU254_RS40275 e21181d6ec946fa1aff3fbbc019563c8 350 SUPERFAMILY SSF56801 154 315 2.17E-6 T 28-03-2018 CU254_RS07715 5626cb464895a9cb99a529d34af64824 203 Pfam PF02669 K+-transporting ATPase, c chain 9 195 7.3E-53 T 28-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 CU254_RS07715 5626cb464895a9cb99a529d34af64824 203 PIRSF PIRSF001296 4 201 6.2E-49 T 28-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 CU254_RS07715 5626cb464895a9cb99a529d34af64824 203 Hamap MF_00276 Potassium-transporting ATPase KdpC subunit [kdpC]. 5 198 27.662 T 28-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 CU254_RS16750 8ca0341449a3388547f446a8e6f1eaf1 69 Gene3D G3DSA:1.10.1470.10 1 69 7.6E-18 T 28-03-2018 IPR008462 CsbD-like domain CU254_RS16750 8ca0341449a3388547f446a8e6f1eaf1 69 SUPERFAMILY SSF69047 4 65 9.55E-9 T 28-03-2018 IPR008462 CsbD-like domain CU254_RS16750 8ca0341449a3388547f446a8e6f1eaf1 69 Pfam PF05532 CsbD-like 5 55 7.7E-15 T 28-03-2018 IPR008462 CsbD-like domain CU254_RS34490 2f62bb5b3b3fd156bf7d36f95a71a1c8 63 Gene3D G3DSA:3.30.70.20 1 63 3.0E-7 T 28-03-2018 CU254_RS34490 2f62bb5b3b3fd156bf7d36f95a71a1c8 63 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 6 59 2.1E-11 T 28-03-2018 CU254_RS34490 2f62bb5b3b3fd156bf7d36f95a71a1c8 63 SUPERFAMILY SSF54862 2 61 8.38E-11 T 28-03-2018 CU254_RS20155 91ac75c9e7177b1369284c466492a9df 169 Pfam PF14325 Domain of unknown function (DUF4383) 15 138 5.4E-40 T 28-03-2018 IPR025492 Protein of unknown function DUF4383 CU254_RS40430 89f976aa9d6f1cda73979f6f0bf7b547 271 Pfam PF00005 ABC transporter 47 177 2.8E-19 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS40430 89f976aa9d6f1cda73979f6f0bf7b547 271 SUPERFAMILY SSF52540 45 242 4.65E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS40430 89f976aa9d6f1cda73979f6f0bf7b547 271 Gene3D G3DSA:3.40.50.300 4 258 7.1E-43 T 28-03-2018 CU254_RS40430 89f976aa9d6f1cda73979f6f0bf7b547 271 SMART SM00382 56 230 5.5E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS01195 08771f555446d9323cb1a4d8937d9d3e 172 Gene3D G3DSA:2.40.50.140 99 170 3.9E-7 T 28-03-2018 CU254_RS00310 db26db16c0173cb39c8ce5bdd9648422 709 Gene3D G3DSA:1.25.10.10 2 695 5.3E-9 T 28-03-2018 IPR011989 Armadillo-like helical CU254_RS00310 db26db16c0173cb39c8ce5bdd9648422 709 SUPERFAMILY SSF48371 419 489 1.66E-7 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 CU254_RS00310 db26db16c0173cb39c8ce5bdd9648422 709 SUPERFAMILY SSF48371 527 689 1.66E-7 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 CU254_RS30640 fbdede2997fb77a38a7ad36f89ec8791 119 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 51 114 7.9E-5 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CU254_RS30640 fbdede2997fb77a38a7ad36f89ec8791 119 Gene3D G3DSA:3.10.180.10 1 119 1.7E-22 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS30640 fbdede2997fb77a38a7ad36f89ec8791 119 SUPERFAMILY SSF54593 2 118 1.83E-16 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS36790 573d0a83edf2d1248d08194ce28acbe8 258 SMART SM00849 31 182 1.8E-26 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS36790 573d0a83edf2d1248d08194ce28acbe8 258 Gene3D G3DSA:3.60.15.10 26 251 2.6E-35 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS36790 573d0a83edf2d1248d08194ce28acbe8 258 SUPERFAMILY SSF56281 18 252 2.62E-48 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS36790 573d0a83edf2d1248d08194ce28acbe8 258 Pfam PF00753 Metallo-beta-lactamase superfamily 29 176 9.3E-15 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS22865 4d8c4220054d3e757cbd06d9e3a072ad 631 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 412 618 5.6E-61 T 28-03-2018 IPR017501 Phage infection protein, YhgE, C-terminal CU254_RS22865 4d8c4220054d3e757cbd06d9e3a072ad 631 Pfam PF12698 ABC-2 family transporter protein 414 611 7.6E-14 T 28-03-2018 CU254_RS22865 4d8c4220054d3e757cbd06d9e3a072ad 631 Pfam PF12698 ABC-2 family transporter protein 26 161 3.4E-8 T 28-03-2018 CU254_RS22865 4d8c4220054d3e757cbd06d9e3a072ad 631 Gene3D G3DSA:3.40.1710.10 47 225 3.7E-26 T 28-03-2018 CU254_RS22865 4d8c4220054d3e757cbd06d9e3a072ad 631 Gene3D G3DSA:1.10.287.950 247 358 1.4E-7 T 28-03-2018 CU254_RS22865 4d8c4220054d3e757cbd06d9e3a072ad 631 Gene3D G3DSA:1.10.287.950 359 402 0.007 T 28-03-2018 CU254_RS22865 4d8c4220054d3e757cbd06d9e3a072ad 631 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 9 172 2.4E-52 T 28-03-2018 IPR017500 Phage infection protein, YhgE, N-terminal CU254_RS22865 4d8c4220054d3e757cbd06d9e3a072ad 631 SUPERFAMILY SSF101967 174 268 4.58E-5 T 28-03-2018 CU254_RS22865 4d8c4220054d3e757cbd06d9e3a072ad 631 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 205 230 3.7E-5 T 28-03-2018 IPR023908 xxxLxxG heptad repeat CU254_RS22865 4d8c4220054d3e757cbd06d9e3a072ad 631 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 344 371 6.3E-9 T 28-03-2018 IPR023908 xxxLxxG heptad repeat CU254_RS22865 4d8c4220054d3e757cbd06d9e3a072ad 631 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 184 210 1.4E-6 T 28-03-2018 IPR023908 xxxLxxG heptad repeat CU254_RS40980 ed9df2383029e9df35a63db9a56b4a62 476 Gene3D G3DSA:1.25.40.10 197 469 1.0E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS27815 f619b3430c3a949c7a59baada7899d95 208 Pfam PF02293 AmiS/UreI family transporter 1 165 1.6E-59 T 28-03-2018 IPR003211 AmiS/UreI transporter GO:0006810|GO:0016020 CU254_RS38695 8e329262c110e3f02225da85fd17c4d6 92 Pfam PF11755 Protein of unknown function (DUF3311) 21 75 7.5E-13 T 28-03-2018 IPR021741 Protein of unknown function DUF3311 CU254_RS01575 a275284352cbdd9212b1f0724fc660a4 342 Gene3D G3DSA:3.40.50.720 1 166 1.3E-18 T 28-03-2018 CU254_RS01575 a275284352cbdd9212b1f0724fc660a4 342 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 236 3.5E-37 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CU254_RS01575 a275284352cbdd9212b1f0724fc660a4 342 Gene3D G3DSA:3.90.25.10 167 315 6.8E-16 T 28-03-2018 CU254_RS01575 a275284352cbdd9212b1f0724fc660a4 342 SUPERFAMILY SSF51735 2 311 9.41E-53 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS25570 51d74fc54a76eebd25956f9308ed0857 74 Pfam PF11755 Protein of unknown function (DUF3311) 11 66 5.7E-12 T 28-03-2018 IPR021741 Protein of unknown function DUF3311 CU254_RS11910 0703307d1a791f15feab0cad47270749 440 Pfam PF09594 Glycosyltransferase family 87 158 389 3.6E-6 T 28-03-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 CU254_RS36180 4ec6565a3b2666a44167150ce31d000d 266 PIRSF PIRSF006648 1 266 2.0E-78 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CU254_RS36180 4ec6565a3b2666a44167150ce31d000d 266 Pfam PF01061 ABC-2 type transporter 23 230 8.8E-33 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CU254_RS07175 9f19ff19d0e899835c4008535b495803 176 Pfam PF00583 Acetyltransferase (GNAT) family 55 147 9.4E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS07175 9f19ff19d0e899835c4008535b495803 176 SUPERFAMILY SSF55729 7 174 8.68E-30 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS07175 9f19ff19d0e899835c4008535b495803 176 Gene3D G3DSA:3.40.630.30 6 176 7.5E-34 T 28-03-2018 CU254_RS09420 3b30fb0e65173cb97bbd8480a68f2944 492 SUPERFAMILY SSF117892 65 201 6.15E-26 T 28-03-2018 IPR001107 Band 7 domain CU254_RS09420 3b30fb0e65173cb97bbd8480a68f2944 492 Pfam PF15975 Flotillin 374 475 9.9E-11 T 28-03-2018 IPR031905 Flotillin, C-terminal domain Reactome: R-HSA-8849932 CU254_RS09420 3b30fb0e65173cb97bbd8480a68f2944 492 Pfam PF01145 SPFH domain / Band 7 family 27 213 2.7E-20 T 28-03-2018 IPR001107 Band 7 domain CU254_RS25650 fb0f2d7fe17cddc8dc3cc3385edfbb29 559 Pfam PF08386 TAP-like protein 411 503 1.7E-18 T 28-03-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal CU254_RS25650 fb0f2d7fe17cddc8dc3cc3385edfbb29 559 Gene3D G3DSA:3.40.50.1820 62 494 3.1E-22 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS25650 fb0f2d7fe17cddc8dc3cc3385edfbb29 559 SUPERFAMILY SSF53474 88 136 2.43E-10 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS25650 fb0f2d7fe17cddc8dc3cc3385edfbb29 559 SUPERFAMILY SSF53474 383 476 2.43E-10 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS25650 fb0f2d7fe17cddc8dc3cc3385edfbb29 559 SUPERFAMILY SSF53474 185 280 2.43E-10 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS25650 fb0f2d7fe17cddc8dc3cc3385edfbb29 559 Pfam PF00561 alpha/beta hydrolase fold 92 274 3.1E-9 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS36825 75a8287227d5114188e2c6d54a4f5da2 334 Gene3D G3DSA:3.40.50.300 11 334 1.6E-47 T 28-03-2018 CU254_RS36825 75a8287227d5114188e2c6d54a4f5da2 334 SUPERFAMILY SSF52540 18 238 3.04E-26 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS36825 75a8287227d5114188e2c6d54a4f5da2 334 Pfam PF02374 Anion-transporting ATPase 17 175 2.2E-19 T 28-03-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 CU254_RS20310 44f92188fc8adf8830b489eac0068f56 78 TIGRFAM TIGR00009 L28: ribosomal protein bL28 2 58 1.5E-24 T 28-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS20310 44f92188fc8adf8830b489eac0068f56 78 Pfam PF00830 Ribosomal L28 family 4 61 4.6E-26 T 28-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS20310 44f92188fc8adf8830b489eac0068f56 78 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 67 20.49 T 28-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CU254_RS20310 44f92188fc8adf8830b489eac0068f56 78 SUPERFAMILY SSF143800 2 76 3.14E-28 T 28-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS20310 44f92188fc8adf8830b489eac0068f56 78 Gene3D G3DSA:2.30.170.40 2 75 1.6E-28 T 28-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS20830 424ba97a3cdca03b9daee96d71fccbaa 108 SUPERFAMILY SSF54909 1 95 4.42E-25 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS20830 424ba97a3cdca03b9daee96d71fccbaa 108 Gene3D G3DSA:3.30.70.100 1 102 7.8E-20 T 28-03-2018 CU254_RS20830 424ba97a3cdca03b9daee96d71fccbaa 108 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 74 1.7E-16 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain CU254_RS14215 06bffa04a4f5a3022be3396cfc6ddf97 315 SUPERFAMILY SSF49785 194 296 4.25E-6 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS14215 06bffa04a4f5a3022be3396cfc6ddf97 315 Gene3D G3DSA:3.40.50.10140 2 156 4.9E-12 T 28-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 CU254_RS14215 06bffa04a4f5a3022be3396cfc6ddf97 315 SUPERFAMILY SSF52200 6 128 7.59E-7 T 28-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 CU254_RS14215 06bffa04a4f5a3022be3396cfc6ddf97 315 Pfam PF08357 SEFIR domain 6 140 7.4E-17 T 28-03-2018 IPR013568 SEFIR domain CU254_RS23420 14f261e4d305677ce6bd5c395c18cf47 490 Pfam PF00890 FAD binding domain 22 467 8.1E-45 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CU254_RS23420 14f261e4d305677ce6bd5c395c18cf47 490 SUPERFAMILY SSF51905 429 486 1.07E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS23420 14f261e4d305677ce6bd5c395c18cf47 490 SUPERFAMILY SSF51905 3 156 1.07E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS23420 14f261e4d305677ce6bd5c395c18cf47 490 SUPERFAMILY SSF51905 187 301 1.07E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS23420 14f261e4d305677ce6bd5c395c18cf47 490 SUPERFAMILY SSF56425 299 412 2.58E-20 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CU254_RS23420 14f261e4d305677ce6bd5c395c18cf47 490 Gene3D G3DSA:3.50.50.60 11 488 2.1E-70 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS23420 14f261e4d305677ce6bd5c395c18cf47 490 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 206 231 8.0E-5 T 28-03-2018 CU254_RS23420 14f261e4d305677ce6bd5c395c18cf47 490 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 22 44 8.0E-5 T 28-03-2018 CU254_RS36090 e3ce830c6ee641828e4ce334c811a59c 407 Pfam PF04286 Protein of unknown function (DUF445) 219 339 1.7E-8 T 28-03-2018 IPR007383 Protein of unknown function DUF445 CU254_RS16705 38dfc3e7792d1e758e7de990eeb81e31 459 SUPERFAMILY SSF53850 27 455 2.28E-53 T 28-03-2018 CU254_RS16705 38dfc3e7792d1e758e7de990eeb81e31 459 Gene3D G3DSA:3.40.190.10 265 431 0.13 T 28-03-2018 CU254_RS16705 38dfc3e7792d1e758e7de990eeb81e31 459 Pfam PF01547 Bacterial extracellular solute-binding protein 62 343 3.5E-26 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 CU254_RS16705 38dfc3e7792d1e758e7de990eeb81e31 459 Gene3D G3DSA:3.40.190.10 43 236 2.1E-29 T 28-03-2018 CU254_RS26230 ad667776d6b3af6c5fb653eab8ae75ed 594 Gene3D G3DSA:3.40.50.300 267 460 1.5E-16 T 28-03-2018 CU254_RS26230 ad667776d6b3af6c5fb653eab8ae75ed 594 Pfam PF07728 AAA domain (dynein-related subfamily) 315 455 8.4E-11 T 28-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 CU254_RS26230 ad667776d6b3af6c5fb653eab8ae75ed 594 SUPERFAMILY SSF52540 353 505 1.01E-15 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS26230 ad667776d6b3af6c5fb653eab8ae75ed 594 SUPERFAMILY SSF52540 272 310 1.01E-15 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS24495 d9683d8b851115233559c77eeab0cf87 90 Pfam PF02325 YGGT family 7 87 1.6E-13 T 28-03-2018 IPR003425 CCB3/YggT GO:0016020 CU254_RS13755 dc31a1a20866f6f7a50f34c9388b6945 132 Gene3D G3DSA:3.30.70.1060 1 132 4.1E-37 T 28-03-2018 CU254_RS13755 dc31a1a20866f6f7a50f34c9388b6945 132 SUPERFAMILY SSF54909 19 128 2.57E-21 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS13755 dc31a1a20866f6f7a50f34c9388b6945 132 Pfam PF03795 YCII-related domain 38 108 5.1E-9 T 28-03-2018 IPR005545 YCII-related CU254_RS12775 80b33f5bad4b2e08078bf3c85fca8ff5 544 Gene3D G3DSA:3.40.50.880 188 540 1.7E-17 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS29150 6bc3a901902e71c6eab3447cddb17bc4 300 SUPERFAMILY SSF47413 11 67 8.16E-12 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CU254_RS29150 6bc3a901902e71c6eab3447cddb17bc4 300 Pfam PF13560 Helix-turn-helix domain 12 73 5.1E-9 T 28-03-2018 CU254_RS29150 6bc3a901902e71c6eab3447cddb17bc4 300 Gene3D G3DSA:1.10.260.40 3 99 2.5E-13 T 28-03-2018 CU254_RS29150 6bc3a901902e71c6eab3447cddb17bc4 300 SMART SM00530 16 71 3.8E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CU254_RS11530 79cf5ec63980e8c838dd0f78564b150b 181 SUPERFAMILY SSF55729 1 134 4.05E-24 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS11530 79cf5ec63980e8c838dd0f78564b150b 181 Pfam PF00583 Acetyltransferase (GNAT) family 34 130 6.9E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS11530 79cf5ec63980e8c838dd0f78564b150b 181 Gene3D G3DSA:3.40.630.30 1 176 8.1E-23 T 28-03-2018 CU254_RS03925 649b5d5afae24e3b27e7b50698cf9d4a 291 Pfam PF12705 PD-(D/E)XK nuclease superfamily 25 273 8.6E-32 T 28-03-2018 CU254_RS03925 649b5d5afae24e3b27e7b50698cf9d4a 291 Gene3D G3DSA:3.90.320.10 12 215 1.9E-17 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 CU254_RS11090 10dfc5f31f3f9db7d7ea3d1672e925a9 283 TIGRFAM TIGR04222 near_uncomplex: TIGR04222 domain 35 270 1.0E-29 T 28-03-2018 IPR026467 Ser/Gly rich, Cys interspersed, C-terminal domain CU254_RS01235 3066542924755d2391e659b2c86d6972 423 Gene3D G3DSA:3.40.50.300 175 415 5.9E-29 T 28-03-2018 CU254_RS01235 3066542924755d2391e659b2c86d6972 423 Pfam PF13614 AAA domain 178 322 1.8E-11 T 28-03-2018 IPR025669 AAA domain CU254_RS01235 3066542924755d2391e659b2c86d6972 423 SUPERFAMILY SSF52540 177 412 1.54E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS20805 4b94ab8cc7d042d605fc55f882efe890 685 Gene3D G3DSA:3.30.420.40 2 289 1.5E-5 T 28-03-2018 CU254_RS20805 4b94ab8cc7d042d605fc55f882efe890 685 Pfam PF01968 Hydantoinase/oxoprolinase 200 485 5.3E-97 T 28-03-2018 IPR002821 Hydantoinase/oxoprolinase GO:0016787 Reactome: R-HSA-174403 CU254_RS20805 4b94ab8cc7d042d605fc55f882efe890 685 SUPERFAMILY SSF53067 3 75 2.42E-5 T 28-03-2018 CU254_RS20805 4b94ab8cc7d042d605fc55f882efe890 685 SUPERFAMILY SSF53067 262 401 2.42E-5 T 28-03-2018 CU254_RS20805 4b94ab8cc7d042d605fc55f882efe890 685 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 4 178 3.0E-48 T 28-03-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403 CU254_RS20805 4b94ab8cc7d042d605fc55f882efe890 685 Gene3D G3DSA:3.30.420.40 290 621 0.038 T 28-03-2018 CU254_RS35160 421dbf7c4f819fd1807f42c713d01119 245 Pfam PF14011 EspG family 11 236 5.3E-30 T 28-03-2018 IPR025734 EspG family CU254_RS13025 1fbeac4444f9d33dd3722d28a3aea980 187 Pfam PF04229 GrpB protein 20 183 4.9E-38 T 28-03-2018 IPR007344 GrpB/Dephospho-CoA kinase CU254_RS13025 1fbeac4444f9d33dd3722d28a3aea980 187 Gene3D G3DSA:3.30.460.10 14 186 2.1E-42 T 28-03-2018 CU254_RS13025 1fbeac4444f9d33dd3722d28a3aea980 187 SUPERFAMILY SSF81301 21 183 2.35E-32 T 28-03-2018 CU254_RS35170 a62a4c1a5b3123a373fa3f39d3d5073f 123 Pfam PF03733 Inner membrane component domain 68 118 4.3E-17 T 28-03-2018 IPR005185 Inner membrane component domain CU254_RS35170 a62a4c1a5b3123a373fa3f39d3d5073f 123 Pfam PF03733 Inner membrane component domain 4 54 4.4E-20 T 28-03-2018 IPR005185 Inner membrane component domain CU254_RS35170 a62a4c1a5b3123a373fa3f39d3d5073f 123 PIRSF PIRSF028777 1 123 7.2E-53 T 28-03-2018 IPR031308 Uncharacterised conserved protein UCP028777 CU254_RS13565 15df51a309e6b0027a6664cb85fc402f 348 Gene3D G3DSA:1.10.287.850 72 185 0.0013 T 28-03-2018 CU254_RS31725 06fb481dda963af6789846e2c1c5f6c0 477 Pfam PF13520 Amino acid permease 26 436 1.7E-25 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CU254_RS31725 06fb481dda963af6789846e2c1c5f6c0 477 PIRSF PIRSF006060 3 471 1.3E-48 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CU254_RS21610 b059ae320a0f3d87309d250c3d85a8b0 170 Pfam PF13478 XdhC Rossmann domain 24 156 1.8E-23 T 28-03-2018 IPR027051 XdhC Rossmann domain CU254_RS12050 7b2f52cdd49f42567cc7564d44e6dac4 323 Pfam PF00704 Glycosyl hydrolases family 18 47 256 1.1E-7 T 28-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 CU254_RS12050 7b2f52cdd49f42567cc7564d44e6dac4 323 SUPERFAMILY SSF51445 45 301 2.53E-19 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS12050 7b2f52cdd49f42567cc7564d44e6dac4 323 Gene3D G3DSA:3.20.20.80 44 319 3.0E-26 T 28-03-2018 CU254_RS16695 0a0aeabdab146fb06bccb961424f9f85 289 Gene3D G3DSA:1.10.3720.10 8 276 4.8E-39 T 28-03-2018 CU254_RS16695 0a0aeabdab146fb06bccb961424f9f85 289 SUPERFAMILY SSF161098 17 289 8.78E-60 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS16695 0a0aeabdab146fb06bccb961424f9f85 289 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 274 1.0E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS15035 84ea130b38e071b70ace4fd39ac715e2 302 SUPERFAMILY SSF46785 236 297 2.31E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS15035 84ea130b38e071b70ace4fd39ac715e2 302 SMART SM00418 230 299 8.2E-4 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CU254_RS15035 84ea130b38e071b70ace4fd39ac715e2 302 Gene3D G3DSA:1.10.10.10 199 301 1.7E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS39810 482dc2a7bce2ec68d666ca0b8d0d136f 127 Gene3D G3DSA:3.10.180.10 1 126 4.5E-19 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS39810 482dc2a7bce2ec68d666ca0b8d0d136f 127 SUPERFAMILY SSF54593 3 118 1.25E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS39810 482dc2a7bce2ec68d666ca0b8d0d136f 127 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 112 2.4E-5 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CU254_RS20240 3af94a6dd99385aefb7b6916e28dbb90 198 Pfam PF01066 CDP-alcohol phosphatidyltransferase 21 85 2.9E-14 T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CU254_RS20240 3af94a6dd99385aefb7b6916e28dbb90 198 PIRSF PIRSF000847 16 198 2.2E-42 T 28-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 CU254_RS20240 3af94a6dd99385aefb7b6916e28dbb90 198 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 63 85 - T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CU254_RS26520 50efcfb39381177d5531a14c47e8b52c 493 Pfam PF13777 Domain of unknown function (DUF4173) 261 450 5.0E-58 T 28-03-2018 IPR025231 Domain of unknown function DUF4173 CU254_RS17380 8ab34334eacbec1ccfe0be811efc7963 290 SUPERFAMILY SSF53335 17 234 5.88E-43 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS17380 8ab34334eacbec1ccfe0be811efc7963 290 Gene3D G3DSA:3.40.50.150 10 279 6.5E-41 T 28-03-2018 CU254_RS17380 8ab34334eacbec1ccfe0be811efc7963 290 Pfam PF13649 Methyltransferase domain 56 150 1.8E-22 T 28-03-2018 CU254_RS04010 ed70377def509c13b1c05b1d002bf088 265 SUPERFAMILY SSF56112 31 188 2.38E-9 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS04010 ed70377def509c13b1c05b1d002bf088 265 TIGRFAM TIGR02569 TIGR02569_actnb: TIGR02569 family protein 7 258 3.8E-61 T 28-03-2018 IPR013402 Conserved hypothetical protein CHP02569 CU254_RS16375 7796a31673abc274e4be6c0a864aee09 777 SUPERFAMILY SSF56784 21 134 1.95E-13 T 28-03-2018 IPR023214 HAD-like domain CU254_RS16375 7796a31673abc274e4be6c0a864aee09 777 Gene3D G3DSA:3.40.50.1000 7 131 8.1E-13 T 28-03-2018 IPR023214 HAD-like domain CU254_RS23090 0685954437f556884a140399397a2189 258 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 183 0.006 T 28-03-2018 CU254_RS23090 0685954437f556884a140399397a2189 258 SUPERFAMILY SSF51735 7 235 6.2E-50 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS23090 0685954437f556884a140399397a2189 258 Pfam PF00106 short chain dehydrogenase 8 194 1.4E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23090 0685954437f556884a140399397a2189 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 1.2E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23090 0685954437f556884a140399397a2189 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 1.2E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23090 0685954437f556884a140399397a2189 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 1.2E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23090 0685954437f556884a140399397a2189 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 1.1E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23090 0685954437f556884a140399397a2189 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 1.1E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23090 0685954437f556884a140399397a2189 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 1.1E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23090 0685954437f556884a140399397a2189 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 1.1E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23090 0685954437f556884a140399397a2189 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.1E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CU254_RS23090 0685954437f556884a140399397a2189 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CU254_RS23090 0685954437f556884a140399397a2189 258 Gene3D G3DSA:3.40.50.720 5 249 8.1E-51 T 28-03-2018 CU254_RS31020 e3df8de83d73c31a9fdfed3ad5a8e641 192 Pfam PF00857 Isochorismatase family 3 184 4.2E-30 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CU254_RS31020 e3df8de83d73c31a9fdfed3ad5a8e641 192 Gene3D G3DSA:3.40.50.850 1 188 1.5E-52 T 28-03-2018 CU254_RS31020 e3df8de83d73c31a9fdfed3ad5a8e641 192 SUPERFAMILY SSF52499 2 186 1.57E-45 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CU254_RS18505 9fe4c4145838c40efe57a5504432b8b8 271 Gene3D G3DSA:3.40.50.300 2 268 2.3E-78 T 28-03-2018 CU254_RS18505 9fe4c4145838c40efe57a5504432b8b8 271 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 228 260 4.0E-6 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CU254_RS18505 9fe4c4145838c40efe57a5504432b8b8 271 SUPERFAMILY SSF52540 5 248 1.36E-73 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS18505 9fe4c4145838c40efe57a5504432b8b8 271 SMART SM00382 35 225 2.9E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS18505 9fe4c4145838c40efe57a5504432b8b8 271 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS18505 9fe4c4145838c40efe57a5504432b8b8 271 Pfam PF00005 ABC transporter 26 176 5.4E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS38075 186ea2a32726d9ccb2aa2aef27e23330 234 Pfam PF09335 SNARE associated Golgi protein 49 176 3.3E-26 T 28-03-2018 IPR032816 SNARE associated Golgi protein CU254_RS18375 78599e0032ac7037e755dcb868165e39 112 Pfam PF03795 YCII-related domain 19 109 7.5E-14 T 28-03-2018 IPR005545 YCII-related CU254_RS18375 78599e0032ac7037e755dcb868165e39 112 Gene3D G3DSA:3.30.70.1060 1 112 7.0E-32 T 28-03-2018 CU254_RS18375 78599e0032ac7037e755dcb868165e39 112 SUPERFAMILY SSF54909 10 111 1.39E-26 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS20205 e68fdca0cb56e73dea0d8eaec5ddcf54 124 Pfam PF12680 SnoaL-like domain 12 114 2.8E-12 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CU254_RS20205 e68fdca0cb56e73dea0d8eaec5ddcf54 124 Gene3D G3DSA:3.10.450.50 4 122 8.6E-19 T 28-03-2018 CU254_RS20205 e68fdca0cb56e73dea0d8eaec5ddcf54 124 SUPERFAMILY SSF54427 8 120 2.27E-32 T 28-03-2018 IPR032710 NTF2-like domain CU254_RS28200 b9ad64a67dd2e270beb098a0ece286da 183 Gene3D G3DSA:2.40.440.10 2 175 8.8E-5 T 28-03-2018 CU254_RS28200 b9ad64a67dd2e270beb098a0ece286da 183 Pfam PF03734 L,D-transpeptidase catalytic domain 31 174 2.8E-5 T 28-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CU254_RS13105 d86b2fd5a90e0cf685bdcc3df89f3cd7 208 SUPERFAMILY SSF51197 32 203 3.98E-42 T 28-03-2018 CU254_RS13105 d86b2fd5a90e0cf685bdcc3df89f3cd7 208 Gene3D G3DSA:2.60.120.590 36 204 5.9E-31 T 28-03-2018 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like CU254_RS13105 d86b2fd5a90e0cf685bdcc3df89f3cd7 208 Pfam PF13532 2OG-Fe(II) oxygenase superfamily 90 203 4.9E-13 T 28-03-2018 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like CU254_RS26345 2306f099b53d63c640387159aa17e91e 246 Pfam PF01061 ABC-2 type transporter 9 207 1.5E-15 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CU254_RS26345 2306f099b53d63c640387159aa17e91e 246 PIRSF PIRSF006648 7 244 1.3E-18 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CU254_RS29625 8af48353a9d98477923e493f6140612b 109 Pfam PF12680 SnoaL-like domain 10 96 4.4E-8 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CU254_RS29625 8af48353a9d98477923e493f6140612b 109 SUPERFAMILY SSF54427 3 103 5.19E-16 T 28-03-2018 IPR032710 NTF2-like domain CU254_RS29625 8af48353a9d98477923e493f6140612b 109 Gene3D G3DSA:3.10.450.50 1 107 8.2E-16 T 28-03-2018 CU254_RS34990 9175747d1b58df35d6fe9583d9180a92 279 Gene3D G3DSA:3.40.50.300 1 259 4.1E-61 T 28-03-2018 CU254_RS34990 9175747d1b58df35d6fe9583d9180a92 279 Pfam PF00005 ABC transporter 22 158 1.1E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS34990 9175747d1b58df35d6fe9583d9180a92 279 SMART SM00382 29 215 2.9E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS34990 9175747d1b58df35d6fe9583d9180a92 279 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CU254_RS34990 9175747d1b58df35d6fe9583d9180a92 279 SUPERFAMILY SSF52540 3 226 2.66E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS16755 0c71e220ae5bcdfd07438434892bab54 153 Pfam PF03780 Asp23 family, cell envelope-related function 26 135 7.4E-32 T 28-03-2018 IPR005531 Alkaline shock protein Asp23 CU254_RS20835 0dc26cc4cc54bca46004b92d1a2a9087 441 Pfam PF02687 FtsX-like permease family 86 170 2.4E-8 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CU254_RS38460 b2d5d43636e1bd44c3efaaa686050437 213 Pfam PF04892 VanZ like family 50 183 4.0E-22 T 28-03-2018 IPR006976 VanZ-like CU254_RS18880 a1b89ab94009b2e4daf1dcbd5c34625e 213 Pfam PF12833 Helix-turn-helix domain 123 194 6.1E-9 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS18880 a1b89ab94009b2e4daf1dcbd5c34625e 213 SMART SM00342 120 193 5.0E-4 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CU254_RS18880 a1b89ab94009b2e4daf1dcbd5c34625e 213 Gene3D G3DSA:1.10.10.60 144 207 3.3E-5 T 28-03-2018 CU254_RS04850 6150a83ca29326ff04f9948c88dd3e52 297 PIRSF PIRSF003097 1 297 2.3E-73 T 28-03-2018 IPR004513 Cell division protein FtsX GO:0007049|GO:0016021 CU254_RS04850 6150a83ca29326ff04f9948c88dd3e52 297 Pfam PF02687 FtsX-like permease family 203 285 7.7E-6 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CU254_RS35420 2f44b0627461d0532512718a623abc14 96 Pfam PF04226 Transglycosylase associated protein 36 84 1.5E-10 T 28-03-2018 IPR007341 Transglycosylase-associated protein GO:0016021 CU254_RS40805 e029174089b4d525d501e66327e15076 369 Pfam PF06224 Winged helix DNA-binding domain 35 353 3.6E-77 T 28-03-2018 IPR009351 Protein of unknown function DUF1006 CU254_RS09385 fd249ceb72052e463e0786f0f88c457a 113 Gene3D G3DSA:1.10.287.850 1 44 0.035 T 28-03-2018 CU254_RS09385 fd249ceb72052e463e0786f0f88c457a 113 Gene3D G3DSA:1.10.287.1060 49 102 0.037 T 28-03-2018 CU254_RS08590 2085008569067b80ac4ff2d72960e3c6 212 Pfam PF04973 Nicotinamide mononucleotide transporter 18 196 9.8E-40 T 28-03-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 CU254_RS42570 b863028177f410c6060f117b46c31936 171 Pfam PF15891 Nucleoside 2-deoxyribosyltransferase like 17 121 2.8E-14 T 28-03-2018 CU254_RS05950 ad12f4ed42a16c8c52021f90d7da8ad9 416 Pfam PF01548 Transposase 19 170 5.1E-36 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CU254_RS05950 ad12f4ed42a16c8c52021f90d7da8ad9 416 Pfam PF02371 Transposase IS116/IS110/IS902 family 278 362 2.8E-17 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CU254_RS11805 7556bce4f6d52b0dcb74783db553e332 482 Pfam PF01458 Uncharacterized protein family (UPF0051) 228 453 6.7E-77 T 28-03-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 CU254_RS11805 7556bce4f6d52b0dcb74783db553e332 482 SUPERFAMILY SSF101960 48 479 4.71E-141 T 28-03-2018 CU254_RS11805 7556bce4f6d52b0dcb74783db553e332 482 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 26 473 1.6E-221 T 28-03-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 CU254_RS36655 8ae3b5ab110d0af7dcddbe305c710d39 401 Gene3D G3DSA:1.20.1250.20 2 187 2.7E-7 T 28-03-2018 CU254_RS36655 8ae3b5ab110d0af7dcddbe305c710d39 401 SUPERFAMILY SSF103473 8 383 4.45E-19 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS36655 8ae3b5ab110d0af7dcddbe305c710d39 401 Gene3D G3DSA:1.20.1250.20 204 390 1.2E-5 T 28-03-2018 CU254_RS00360 c9381f6a28bedcee76b7d4f45f9c1f00 193 SUPERFAMILY SSF46689 2 74 9.23E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS00360 c9381f6a28bedcee76b7d4f45f9c1f00 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 54 4.2E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS00360 c9381f6a28bedcee76b7d4f45f9c1f00 193 Gene3D G3DSA:1.10.357.10 9 193 4.6E-23 T 28-03-2018 CU254_RS20325 cf1949ea45cabb4bbbd4a81dab2bb8c0 52 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 38 1.4E-11 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS20325 cf1949ea45cabb4bbbd4a81dab2bb8c0 52 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 51 12.378 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS20325 cf1949ea45cabb4bbbd4a81dab2bb8c0 52 Pfam PF01783 Ribosomal L32p protein family 2 38 2.0E-12 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CU254_RS20325 cf1949ea45cabb4bbbd4a81dab2bb8c0 52 SUPERFAMILY SSF57829 1 39 1.04E-9 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CU254_RS36110 b16b6c6ab219d26eda1bf56adbe23fcc 294 Gene3D G3DSA:1.10.3470.10 8 283 1.8E-28 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CU254_RS36110 b16b6c6ab219d26eda1bf56adbe23fcc 294 SUPERFAMILY SSF81345 13 267 9.55E-34 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CU254_RS36110 b16b6c6ab219d26eda1bf56adbe23fcc 294 Pfam PF00950 ABC 3 transport family 20 268 3.0E-43 T 28-03-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 CU254_RS33865 b3ac076338c449bbb9f1d0646da8b33d 254 PRINTS PR00164 ABC-2 type transport system membrane protein signature 137 161 6.1E-7 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CU254_RS33865 b3ac076338c449bbb9f1d0646da8b33d 254 PRINTS PR00164 ABC-2 type transport system membrane protein signature 23 44 6.1E-7 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CU254_RS33865 b3ac076338c449bbb9f1d0646da8b33d 254 PRINTS PR00164 ABC-2 type transport system membrane protein signature 174 193 6.1E-7 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CU254_RS33865 b3ac076338c449bbb9f1d0646da8b33d 254 PRINTS PR00164 ABC-2 type transport system membrane protein signature 102 127 6.1E-7 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CU254_RS33865 b3ac076338c449bbb9f1d0646da8b33d 254 Pfam PF01061 ABC-2 type transporter 5 215 6.5E-34 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CU254_RS33865 b3ac076338c449bbb9f1d0646da8b33d 254 PIRSF PIRSF006648 1 254 1.4E-45 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CU254_RS11080 01bc1b581ba41b452d11d530ebe12581 230 Gene3D G3DSA:3.30.70.1100 128 227 9.7E-31 T 28-03-2018 CU254_RS11080 01bc1b581ba41b452d11d530ebe12581 230 Gene3D G3DSA:3.30.70.1030 8 127 7.0E-39 T 28-03-2018 CU254_RS11080 01bc1b581ba41b452d11d530ebe12581 230 SUPERFAMILY SSF54909 4 229 3.75E-78 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS11080 01bc1b581ba41b452d11d530ebe12581 230 Pfam PF06778 Chlorite dismutase 34 219 7.1E-74 T 28-03-2018 IPR010644 Putative heme-dependent peroxidase/Chlorite dismutase CU254_RS05060 2926644b1093fc1e94b08dff14844297 234 Gene3D G3DSA:3.40.50.150 14 216 2.6E-30 T 28-03-2018 CU254_RS05060 2926644b1093fc1e94b08dff14844297 234 SUPERFAMILY SSF53335 22 217 2.41E-27 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS05060 2926644b1093fc1e94b08dff14844297 234 Pfam PF13649 Methyltransferase domain 74 163 4.2E-13 T 28-03-2018 CU254_RS12005 e8e7f34c73abcff16630dffecc6f906d 277 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 102 122 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CU254_RS12005 e8e7f34c73abcff16630dffecc6f906d 277 Pfam PF00378 Enoyl-CoA hydratase/isomerase 12 260 2.9E-43 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CU254_RS12005 e8e7f34c73abcff16630dffecc6f906d 277 Gene3D G3DSA:1.10.12.10 216 265 3.6E-12 T 28-03-2018 IPR014748 Crontonase, C-terminal CU254_RS12005 e8e7f34c73abcff16630dffecc6f906d 277 SUPERFAMILY SSF52096 3 264 4.44E-69 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CU254_RS12005 e8e7f34c73abcff16630dffecc6f906d 277 Gene3D G3DSA:3.90.226.10 6 215 6.5E-58 T 28-03-2018 CU254_RS33085 97355f9bb1314c7896c9c2d0194d1deb 90 Gene3D G3DSA:1.10.287.850 6 84 1.3E-10 T 28-03-2018 CU254_RS33085 97355f9bb1314c7896c9c2d0194d1deb 90 SUPERFAMILY SSF140453 7 73 1.83E-12 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CU254_RS33085 97355f9bb1314c7896c9c2d0194d1deb 90 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 8 73 1.3E-12 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CU254_RS33085 97355f9bb1314c7896c9c2d0194d1deb 90 Pfam PF06013 Proteins of 100 residues with WXG 7 73 2.8E-11 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CU254_RS20570 07512425f1d7f33439fd25738c718bce 252 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 7 180 2.7E-26 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CU254_RS20570 07512425f1d7f33439fd25738c718bce 252 Gene3D G3DSA:3.40.50.1110 1 191 1.2E-34 T 28-03-2018 CU254_RS20570 07512425f1d7f33439fd25738c718bce 252 SUPERFAMILY SSF52266 3 189 7.5E-37 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CU254_RS17650 1031f2ae13ce47ad82c8de5b108b62ef 244 SUPERFAMILY SSF56529 2 240 4.43E-56 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CU254_RS17650 1031f2ae13ce47ad82c8de5b108b62ef 244 Gene3D G3DSA:3.90.850.10 1 244 7.7E-35 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CU254_RS17650 1031f2ae13ce47ad82c8de5b108b62ef 244 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 126 238 1.4E-6 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CU254_RS05350 218cc6330d147d8a5e870dc988cc3c32 329 Gene3D G3DSA:1.20.5.50 15 97 3.2E-5 T 28-03-2018 CU254_RS13780 905697e8305a796a7b3d4e1fc75482f4 101 SUPERFAMILY SSF46565 23 45 2.62E-5 T 28-03-2018 IPR001623 DnaJ domain CU254_RS13780 905697e8305a796a7b3d4e1fc75482f4 101 Gene3D G3DSA:1.10.287.110 5 96 3.2E-4 T 28-03-2018 IPR001623 DnaJ domain CU254_RS01090 c868f7bb573f92b89ddd42749f77ce1c 348 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 190 1.1E-21 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CU254_RS01090 c868f7bb573f92b89ddd42749f77ce1c 348 Gene3D G3DSA:3.40.50.720 2 320 1.1E-37 T 28-03-2018 CU254_RS01090 c868f7bb573f92b89ddd42749f77ce1c 348 SUPERFAMILY SSF51735 1 316 8.35E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS20525 989325a92d67fa0b7b35b993799e587d 194 Gene3D G3DSA:3.40.30.10 43 175 6.2E-12 T 28-03-2018 CU254_RS20525 989325a92d67fa0b7b35b993799e587d 194 Gene3D G3DSA:3.40.30.10 1 42 5.8E-5 T 28-03-2018 CU254_RS20525 989325a92d67fa0b7b35b993799e587d 194 SUPERFAMILY SSF52833 4 152 1.08E-15 T 28-03-2018 IPR012336 Thioredoxin-like fold CU254_RS01840 beed179769f9715d2dc129c72be15770 111 Gene3D G3DSA:1.10.287.1060 6 102 9.4E-5 T 28-03-2018 CU254_RS03220 f919417d488219d6840dd5948e9f6a28 106 Pfam PF07179 SseB protein N-terminal domain 27 93 1.1E-4 T 28-03-2018 IPR009839 SseB protein N-terminal domain CU254_RS18890 7fbe7428252342efad5959e48238d74c 236 Gene3D G3DSA:3.40.50.880 1 231 1.5E-55 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS18890 7fbe7428252342efad5959e48238d74c 236 SUPERFAMILY SSF52317 1 227 1.97E-70 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CU254_RS18890 7fbe7428252342efad5959e48238d74c 236 Pfam PF01965 DJ-1/PfpI family 27 225 3.1E-16 T 28-03-2018 IPR002818 DJ-1/PfpI CU254_RS42565 7c041c43e7fdb64f829f43e5f230d97c 141 SUPERFAMILY SSF54197 17 128 2.72E-19 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CU254_RS42565 7c041c43e7fdb64f829f43e5f230d97c 141 Pfam PF01230 HIT domain 32 119 2.0E-9 T 28-03-2018 IPR001310 Histidine triad (HIT) protein CU254_RS42565 7c041c43e7fdb64f829f43e5f230d97c 141 Gene3D G3DSA:3.30.428.10 11 141 4.0E-19 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CU254_RS37370 762875d7a4c8234b9cbfa3414888d265 639 Pfam PF10101 Predicted membrane protein (DUF2339) 457 633 3.6E-11 T 28-03-2018 IPR019286 Protein of unknown function DUF2339, transmembrane CU254_RS37370 762875d7a4c8234b9cbfa3414888d265 639 Pfam PF10101 Predicted membrane protein (DUF2339) 157 452 1.6E-22 T 28-03-2018 IPR019286 Protein of unknown function DUF2339, transmembrane CU254_RS28855 646072b6ab33a0f55b95172bc1f2eec8 249 Gene3D G3DSA:1.10.443.10 69 195 5.4E-20 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CU254_RS28855 646072b6ab33a0f55b95172bc1f2eec8 249 Pfam PF00589 Phage integrase family 123 194 4.5E-10 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CU254_RS28855 646072b6ab33a0f55b95172bc1f2eec8 249 SUPERFAMILY SSF56349 113 194 2.3E-16 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CU254_RS05955 199a6f47148ca7bd87889d0536033f42 207 SUPERFAMILY SSF141571 28 204 1.37E-42 T 28-03-2018 CU254_RS05955 199a6f47148ca7bd87889d0536033f42 207 Pfam PF13599 Pentapeptide repeats (9 copies) 33 101 6.5E-10 T 28-03-2018 IPR001646 Pentapeptide repeat CU254_RS05955 199a6f47148ca7bd87889d0536033f42 207 Pfam PF13599 Pentapeptide repeats (9 copies) 113 186 2.3E-10 T 28-03-2018 IPR001646 Pentapeptide repeat CU254_RS05955 199a6f47148ca7bd87889d0536033f42 207 Gene3D G3DSA:2.160.20.80 20 207 3.8E-37 T 28-03-2018 CU254_RS09305 808eb19348ec9490f0e8ea42f13216cb 120 Pfam PF06993 Protein of unknown function (DUF1304) 10 116 1.9E-42 T 28-03-2018 IPR009732 Protein of unknown function DUF1304 CU254_RS40875 49b82584c9861824d5a05a959ed12c43 169 Pfam PF15891 Nucleoside 2-deoxyribosyltransferase like 17 121 2.3E-15 T 28-03-2018 CU254_RS19660 ec03a73396f99c0fcf7e4b2a42c04a73 137 SUPERFAMILY SSF54593 13 136 1.38E-19 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS19660 ec03a73396f99c0fcf7e4b2a42c04a73 137 Gene3D G3DSA:3.10.180.10 6 137 1.8E-18 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS26090 99e50f6abf61c094a80af7afccc0fc4f 322 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 31 318 9.6E-32 T 28-03-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 CU254_RS26090 99e50f6abf61c094a80af7afccc0fc4f 322 SUPERFAMILY SSF51197 30 320 7.33E-59 T 28-03-2018 CU254_RS26090 99e50f6abf61c094a80af7afccc0fc4f 322 Gene3D G3DSA:3.60.130.10 8 322 2.9E-56 T 28-03-2018 CU254_RS06610 48da9da296bc2d9b1909ae6f63829478 455 Gene3D G3DSA:1.25.40.10 89 229 1.7E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS06610 48da9da296bc2d9b1909ae6f63829478 455 Gene3D G3DSA:1.25.40.10 266 438 0.17 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS06610 48da9da296bc2d9b1909ae6f63829478 455 Gene3D G3DSA:1.25.40.10 4 76 0.0096 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS30265 d1ef0891c609c9d61a03f44d6cb340e5 560 Gene3D G3DSA:3.20.20.370 252 560 4.4E-16 T 28-03-2018 CU254_RS30265 d1ef0891c609c9d61a03f44d6cb340e5 560 Pfam PF10096 Uncharacterized protein conserved in bacteria (DUF2334) 272 544 3.0E-52 T 28-03-2018 IPR018763 Protein of unknown function DUF2334 CU254_RS15835 79758c50b321e92554291b1a915dfa84 544 Gene3D G3DSA:3.30.420.40 164 303 0.0024 T 28-03-2018 CU254_RS15835 79758c50b321e92554291b1a915dfa84 544 SUPERFAMILY SSF55821 367 539 1.77E-5 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CU254_RS15835 79758c50b321e92554291b1a915dfa84 544 Pfam PF02543 Carbamoyltransferase N-terminus 3 322 1.1E-51 T 28-03-2018 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 CU254_RS15835 79758c50b321e92554291b1a915dfa84 544 SUPERFAMILY SSF53067 3 87 2.62E-18 T 28-03-2018 CU254_RS15835 79758c50b321e92554291b1a915dfa84 544 SUPERFAMILY SSF53067 121 326 2.62E-18 T 28-03-2018 CU254_RS15835 79758c50b321e92554291b1a915dfa84 544 Gene3D G3DSA:3.30.420.40 1 163 2.4E-29 T 28-03-2018 CU254_RS15835 79758c50b321e92554291b1a915dfa84 544 Pfam PF16861 Carbamoyltransferase C-terminus 371 540 1.3E-64 T 28-03-2018 IPR031730 Carbamoyltransferase, C-terminal CU254_RS41360 47fa438374cbdb9e07e7c5f5d20b34c3 247 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 7 199 1.4E-27 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase CU254_RS41360 47fa438374cbdb9e07e7c5f5d20b34c3 247 SUPERFAMILY SSF100950 6 209 3.49E-30 T 28-03-2018 CU254_RS41360 47fa438374cbdb9e07e7c5f5d20b34c3 247 Gene3D G3DSA:3.40.50.10420 1 209 1.0E-33 T 28-03-2018 CU254_RS18770 bfd1733ae89c41fcd4114902623ed29f 348 Pfam PF01699 Sodium/calcium exchanger protein 210 340 1.1E-11 T 28-03-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 CU254_RS18770 bfd1733ae89c41fcd4114902623ed29f 348 Pfam PF01699 Sodium/calcium exchanger protein 3 171 1.2E-13 T 28-03-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 CU254_RS34505 0d86078fc499d265f2ece45b236a0363 242 Gene3D G3DSA:3.40.50.150 1 242 6.9E-38 T 28-03-2018 CU254_RS34505 0d86078fc499d265f2ece45b236a0363 242 Pfam PF13649 Methyltransferase domain 40 135 1.8E-14 T 28-03-2018 CU254_RS34505 0d86078fc499d265f2ece45b236a0363 242 SUPERFAMILY SSF53335 19 240 1.24E-32 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS31250 b96ddb9ff2a54a380b51ff4f3826c9d5 144 Pfam PF10739 Protein of unknown function (DUF2550) 10 137 1.8E-44 T 28-03-2018 IPR019675 Protein of unknown function DUF2550 CU254_RS21445 e63027b0daba3d785296f258ff9b77fd 133 Pfam PF06993 Protein of unknown function (DUF1304) 11 131 2.6E-23 T 28-03-2018 IPR009732 Protein of unknown function DUF1304 CU254_RS02530 8efdfb90d0c42cd1cec18bf870fe3bd7 383 Gene3D G3DSA:1.10.510.10 101 361 1.5E-39 T 28-03-2018 CU254_RS02530 8efdfb90d0c42cd1cec18bf870fe3bd7 383 SUPERFAMILY SSF56112 8 331 1.28E-53 T 28-03-2018 IPR011009 Protein kinase-like domain CU254_RS02530 8efdfb90d0c42cd1cec18bf870fe3bd7 383 Pfam PF00069 Protein kinase domain 12 239 4.1E-29 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CU254_RS02530 8efdfb90d0c42cd1cec18bf870fe3bd7 383 Gene3D G3DSA:3.30.200.20 1 100 3.6E-16 T 28-03-2018 CU254_RS31815 f99a157885837fa8c38623e39bd32aa3 514 SUPERFAMILY SSF81340 3 419 6.28E-88 T 28-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 CU254_RS31815 f99a157885837fa8c38623e39bd32aa3 514 SUPERFAMILY SSF54631 426 499 3.16E-6 T 28-03-2018 CU254_RS31815 f99a157885837fa8c38623e39bd32aa3 514 Gene3D G3DSA:1.10.3080.10 1 417 3.4E-72 T 28-03-2018 IPR014743 Chloride channel, core GO:0005216|GO:0055085 Reactome: R-HSA-2672351 CU254_RS31815 f99a157885837fa8c38623e39bd32aa3 514 Pfam PF00571 CBS domain 431 493 6.0E-5 T 28-03-2018 IPR000644 CBS domain CU254_RS31815 f99a157885837fa8c38623e39bd32aa3 514 Gene3D G3DSA:3.10.580.10 418 514 3.3E-7 T 28-03-2018 CU254_RS31815 f99a157885837fa8c38623e39bd32aa3 514 PRINTS PR00762 Chloride channel signature 319 339 3.0E-24 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CU254_RS31815 f99a157885837fa8c38623e39bd32aa3 514 PRINTS PR00762 Chloride channel signature 366 385 3.0E-24 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CU254_RS31815 f99a157885837fa8c38623e39bd32aa3 514 PRINTS PR00762 Chloride channel signature 348 364 3.0E-24 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CU254_RS31815 f99a157885837fa8c38623e39bd32aa3 514 PRINTS PR00762 Chloride channel signature 155 174 3.0E-24 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CU254_RS31815 f99a157885837fa8c38623e39bd32aa3 514 PRINTS PR00762 Chloride channel signature 104 123 3.0E-24 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CU254_RS31815 f99a157885837fa8c38623e39bd32aa3 514 Pfam PF00654 Voltage gated chloride channel 61 397 1.5E-68 T 28-03-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CU254_RS13230 03dbe0b44e1a8fbbe0cdc332bdcd5cb3 168 Gene3D G3DSA:3.40.50.360 1 168 9.0E-22 T 28-03-2018 IPR029039 Flavoprotein-like domain CU254_RS13230 03dbe0b44e1a8fbbe0cdc332bdcd5cb3 168 SUPERFAMILY SSF52218 1 161 1.41E-13 T 28-03-2018 IPR029039 Flavoprotein-like domain CU254_RS13230 03dbe0b44e1a8fbbe0cdc332bdcd5cb3 168 Pfam PF12724 Flavodoxin domain 5 124 3.1E-20 T 28-03-2018 IPR026816 Flavodoxin domain CU254_RS26205 a98e914858200c20178422376d32bead 427 SUPERFAMILY SSF140459 19 163 1.15E-5 T 28-03-2018 CU254_RS26205 a98e914858200c20178422376d32bead 427 Gene3D G3DSA:1.10.287.850 16 105 1.8E-4 T 28-03-2018 CU254_RS17510 0ac4c65716da6777699fd41ff775412a 260 PIRSF PIRSF006648 1 260 3.6E-63 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CU254_RS17510 0ac4c65716da6777699fd41ff775412a 260 Pfam PF01061 ABC-2 type transporter 9 214 2.2E-24 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CU254_RS35895 38aadf9f2c410222e73ef127c3c07a3f 207 Pfam PF05423 Mycobacterium membrane protein 106 191 1.1E-5 T 28-03-2018 IPR008693 Transport accessory protein MmpS CU254_RS32765 84ca3d9e6bf5bb4a028b89962d04a902 304 Pfam PF02646 RmuC family 61 265 8.1E-36 T 28-03-2018 IPR003798 DNA recombination RmuC CU254_RS32765 84ca3d9e6bf5bb4a028b89962d04a902 304 Gene3D G3DSA:1.20.5.340 26 162 0.005 T 28-03-2018 CU254_RS10560 4c4ecb19051640a24643d41340e78e5e 344 Pfam PF03631 Virulence factor BrkB 43 291 2.7E-43 T 28-03-2018 IPR017039 Virulence factor BrkB CU254_RS10560 4c4ecb19051640a24643d41340e78e5e 344 PIRSF PIRSF035875 284 339 110.0 T 28-03-2018 IPR017039 Virulence factor BrkB CU254_RS10560 4c4ecb19051640a24643d41340e78e5e 344 PIRSF PIRSF035875 12 306 2.5E-30 T 28-03-2018 IPR017039 Virulence factor BrkB CU254_RS41040 eac8dbf9f110c4e4b8a27eabc66da9b4 281 Pfam PF14907 Uncharacterised nucleotidyltransferase 38 225 6.5E-19 T 28-03-2018 CU254_RS28785 f6cf711e0c217b9ace9d4520cb59399a 454 SUPERFAMILY SSF53448 47 318 4.5E-26 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS28785 f6cf711e0c217b9ace9d4520cb59399a 454 Gene3D G3DSA:3.90.550.10 33 331 7.7E-30 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS28785 f6cf711e0c217b9ace9d4520cb59399a 454 Pfam PF13641 Glycosyltransferase like family 2 46 298 5.3E-25 T 28-03-2018 CU254_RS23675 71131cc686a793abd62ca29249465b36 133 Gene3D G3DSA:2.60.120.10 4 131 1.1E-24 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS23675 71131cc686a793abd62ca29249465b36 133 Pfam PF07883 Cupin domain 35 91 8.8E-12 T 28-03-2018 IPR013096 Cupin 2, conserved barrel CU254_RS23675 71131cc686a793abd62ca29249465b36 133 SUPERFAMILY SSF51182 6 127 4.67E-27 T 28-03-2018 IPR011051 RmlC-like cupin domain CU254_RS02835 eb40719d5268df969d008cb88cfe443f 410 Pfam PF02653 Branched-chain amino acid transport system / permease component 47 335 5.1E-36 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CU254_RS02835 eb40719d5268df969d008cb88cfe443f 410 Gene3D G3DSA:1.10.3470.10 12 349 4.1E-43 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CU254_RS04555 4ce3637f5f811629b133d6842a6b3d4b 267 Pfam PF03704 Bacterial transcriptional activator domain 139 265 1.4E-18 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CU254_RS04555 4ce3637f5f811629b133d6842a6b3d4b 267 Gene3D G3DSA:1.10.10.10 33 132 3.0E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS04555 4ce3637f5f811629b133d6842a6b3d4b 267 SUPERFAMILY SSF48452 166 266 1.56E-17 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS04555 4ce3637f5f811629b133d6842a6b3d4b 267 SMART SM01043 131 266 8.7E-27 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CU254_RS04555 4ce3637f5f811629b133d6842a6b3d4b 267 Gene3D G3DSA:1.25.40.10 133 267 5.9E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS08275 3cebe6ca1808323fe9fa4bd65f4b5b06 71 Pfam PF08410 Domain of unknown function (DUF1737) 10 55 1.3E-17 T 28-03-2018 IPR013619 Domain of unknown function DUF1737 CU254_RS39520 37f94c9827d5682786d97e15f7fb0e45 408 SUPERFAMILY SSF49879 307 405 4.02E-29 T 28-03-2018 IPR008984 SMAD/FHA domain GO:0005515 CU254_RS39520 37f94c9827d5682786d97e15f7fb0e45 408 SMART SM00240 334 384 3.3E-13 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CU254_RS39520 37f94c9827d5682786d97e15f7fb0e45 408 Pfam PF00498 FHA domain 336 398 2.3E-17 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CU254_RS39520 37f94c9827d5682786d97e15f7fb0e45 408 Pfam PF12401 Protein of unknown function (DUF2662) 5 118 1.3E-37 T 28-03-2018 IPR022128 Domain of unknown function DUF3662 CU254_RS39520 37f94c9827d5682786d97e15f7fb0e45 408 Gene3D G3DSA:2.60.200.20 288 407 1.2E-27 T 28-03-2018 CU254_RS14745 faeee499e9e2b3e0c2faf813d13cb8cf 351 Gene3D G3DSA:3.40.50.2000 29 331 7.4E-21 T 28-03-2018 CU254_RS14745 faeee499e9e2b3e0c2faf813d13cb8cf 351 Pfam PF00534 Glycosyl transferases group 1 237 324 6.6E-11 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CU254_RS14745 faeee499e9e2b3e0c2faf813d13cb8cf 351 SUPERFAMILY SSF53756 37 336 1.3E-27 T 28-03-2018 CU254_RS11770 204edd8fe4d6456784c089910e7091d2 309 Pfam PF00487 Fatty acid desaturase 49 267 4.8E-18 T 28-03-2018 IPR005804 Fatty acid desaturase domain GO:0006629 CU254_RS11770 204edd8fe4d6456784c089910e7091d2 309 PRINTS PR00075 Fatty acid desaturase family 1 signature 49 71 2.1E-19 T 28-03-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 CU254_RS11770 204edd8fe4d6456784c089910e7091d2 309 PRINTS PR00075 Fatty acid desaturase family 1 signature 252 266 2.1E-19 T 28-03-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 CU254_RS11770 204edd8fe4d6456784c089910e7091d2 309 PRINTS PR00075 Fatty acid desaturase family 1 signature 209 230 2.1E-19 T 28-03-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 CU254_RS11770 204edd8fe4d6456784c089910e7091d2 309 PRINTS PR00075 Fatty acid desaturase family 1 signature 72 92 2.1E-19 T 28-03-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 CU254_RS10250 9017be35456837c18fd46fb9a4fd6345 135 Pfam PF05331 Protein of unknown function (DUF742) 18 135 4.7E-32 T 28-03-2018 IPR007995 Protein of unknown function DUF742 CU254_RS10250 9017be35456837c18fd46fb9a4fd6345 135 Gene3D G3DSA:1.10.10.10 57 123 3.4E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS12275 f1846bb39922a928b6865c9a8a518f80 273 Pfam PF14011 EspG family 15 250 2.1E-58 T 28-03-2018 IPR025734 EspG family CU254_RS14930 1fe03a95e508cbb290aa04cebfee1dd6 414 SUPERFAMILY SSF55874 304 411 1.43E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS14930 1fe03a95e508cbb290aa04cebfee1dd6 414 Pfam PF13796 Putative sensor 56 196 7.6E-11 T 28-03-2018 IPR025828 Putative sensor domain CU254_RS14930 1fe03a95e508cbb290aa04cebfee1dd6 414 Gene3D G3DSA:3.30.565.10 288 414 1.8E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS14930 1fe03a95e508cbb290aa04cebfee1dd6 414 Pfam PF07730 Histidine kinase 225 292 7.2E-14 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CU254_RS41180 de226ac574df3782e6c146597cd44b93 139 Gene3D G3DSA:1.10.10.10 2 124 1.1E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS29225 6927f043f0188d3398031066ca9838fa 349 Pfam PF00155 Aminotransferase class I and II 27 346 7.0E-46 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CU254_RS29225 6927f043f0188d3398031066ca9838fa 349 Gene3D G3DSA:3.40.640.10 58 270 3.3E-39 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS29225 6927f043f0188d3398031066ca9838fa 349 Gene3D G3DSA:3.90.1150.10 271 349 9.4E-13 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS29225 6927f043f0188d3398031066ca9838fa 349 SUPERFAMILY SSF53383 11 348 7.48E-69 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS34140 7b0d29ecc268efe55d18fbd968492540 301 Gene3D G3DSA:3.90.550.10 3 300 4.3E-51 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS34140 7b0d29ecc268efe55d18fbd968492540 301 SUPERFAMILY SSF53448 11 291 6.53E-55 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS34140 7b0d29ecc268efe55d18fbd968492540 301 Pfam PF00483 Nucleotidyl transferase 13 275 1.2E-28 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CU254_RS41955 70890eb903e7407121387c18188b071a 311 Pfam PF12079 Protein of unknown function (DUF3558) 132 305 9.5E-22 T 28-03-2018 IPR024520 Protein of unknown function DUF3558 CU254_RS13625 df1ce6ed7a32215029b5e3013db45990 40 Pfam PF10708 Protein of unknown function (DUF2510) 10 37 4.8E-8 T 28-03-2018 IPR018929 Domain of unknown function DUF2510 CU254_RS08115 62788e3e7957d654f15d46b1a1f239df 176 Gene3D G3DSA:3.40.190.10 1 171 8.6E-7 T 28-03-2018 CU254_RS08115 62788e3e7957d654f15d46b1a1f239df 176 Pfam PF12079 Protein of unknown function (DUF3558) 16 171 3.0E-12 T 28-03-2018 IPR024520 Protein of unknown function DUF3558 CU254_RS28545 7fd1b73678877a0b2057d95f3b212bbc 142 SMART SM00347 22 135 0.006 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CU254_RS28545 7fd1b73678877a0b2057d95f3b212bbc 142 Gene3D G3DSA:1.10.10.10 1 142 3.7E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS28545 7fd1b73678877a0b2057d95f3b212bbc 142 SUPERFAMILY SSF46785 8 137 1.3E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS28545 7fd1b73678877a0b2057d95f3b212bbc 142 Pfam PF12802 MarR family 33 85 8.5E-10 T 28-03-2018 CU254_RS32065 d9e875714f223b3fafd0de5bae0e7ae4 392 Pfam PF06772 Bacterial low temperature requirement A protein (LtrA) 16 378 1.1E-92 T 28-03-2018 IPR010640 Low temperature requirement A CU254_RS07865 1f5f8e090ba10f23a22f1d8b081e4d15 110 Gene3D G3DSA:1.10.287.1060 10 107 5.1E-5 T 28-03-2018 CU254_RS07865 1f5f8e090ba10f23a22f1d8b081e4d15 110 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 7 103 6.4E-6 T 28-03-2018 IPR022536 ESX-1 secretion-associated protein EspC GO:0009306 CU254_RS03440 c711d476a0ec4d0c399fe6d534bc76f4 198 Pfam PF12079 Protein of unknown function (DUF3558) 3 191 2.1E-25 T 28-03-2018 IPR024520 Protein of unknown function DUF3558 CU254_RS30850 c55745788310a66d0afe147fa331e911 73 Pfam PF12277 Protein of unknown function (DUF3618) 2 47 2.7E-18 T 28-03-2018 IPR022062 Protein of unknown function DUF3618 CU254_RS27245 1db47354e7f36953c6d078de02787ccf 275 Pfam PF00296 Luciferase-like monooxygenase 35 232 8.0E-13 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS27245 1db47354e7f36953c6d078de02787ccf 275 Gene3D G3DSA:3.20.20.30 9 247 1.2E-23 T 28-03-2018 CU254_RS27245 1db47354e7f36953c6d078de02787ccf 275 SUPERFAMILY SSF51679 12 259 6.92E-25 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS02190 cc52234e18620eb2fe5425bd70e794c2 225 Pfam PF14230 Domain of unknown function (DUF4333) 140 216 3.2E-24 T 28-03-2018 IPR025637 Domain of unknown function DUF4333 CU254_RS22695 7b60cb13e44d3e548303689cf7366572 249 Pfam PF03649 Uncharacterised protein family (UPF0014) 12 239 3.9E-49 T 28-03-2018 IPR005226 UPF0014 family CU254_RS37310 32253222456fd90b7766e085d58511ee 160 TIGRFAM TIGR03941 tRNA_deam_assoc: putative tRNA adenosine deaminase-associated protein 9 155 6.7E-53 T 28-03-2018 IPR023869 tRNA adenosine deaminase-associated protein, putative CU254_RS04055 8783f62b27afff70f3552509838276ed 372 Pfam PF06224 Winged helix DNA-binding domain 41 359 3.5E-36 T 28-03-2018 IPR009351 Protein of unknown function DUF1006 CU254_RS12475 f740ebcdd8ec2a31f2915a0a81b6ba3f 244 Gene3D G3DSA:2.60.40.10 4 223 0.0074 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS03755 3584bcc5914eb9aef453bb69213c6730 218 Gene3D G3DSA:3.40.50.150 6 216 2.0E-28 T 28-03-2018 CU254_RS03755 3584bcc5914eb9aef453bb69213c6730 218 Pfam PF01596 O-methyltransferase 47 214 2.8E-26 T 28-03-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 CU254_RS03755 3584bcc5914eb9aef453bb69213c6730 218 SUPERFAMILY SSF53335 36 215 5.03E-29 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS08900 88703a7ff9886724153c4a95b926947a 383 Gene3D G3DSA:2.102.10.10 205 383 2.4E-41 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CU254_RS08900 88703a7ff9886724153c4a95b926947a 383 Pfam PF00355 Rieske [2Fe-2S] domain 291 355 1.0E-10 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CU254_RS08900 88703a7ff9886724153c4a95b926947a 383 SUPERFAMILY SSF50022 299 381 2.75E-25 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CU254_RS22655 7c976d6c38e4c6451165ec3c13f3dedc 261 Pfam PF07920 Protein of unknown function (DUF1684) 118 255 4.9E-45 T 28-03-2018 IPR012467 Protein of unknown function DUF1684 CU254_RS24500 c21e408edac4b7fd08a42b91b916eb77 190 Hamap MF_01197 Cell division protein SepF [sepF]. 1 181 21.008 T 28-03-2018 IPR023052 Cell division protein SepF GO:0090529 CU254_RS24500 c21e408edac4b7fd08a42b91b916eb77 190 Pfam PF04472 Cell division protein SepF 102 173 4.4E-25 T 28-03-2018 IPR007561 Cell division protein SepF/SepF-related GO:0090529 CU254_RS09020 14bc457b0e231b4e2fee3962e1958b85 425 Gene3D G3DSA:3.40.50.1820 190 404 4.2E-4 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS09020 14bc457b0e231b4e2fee3962e1958b85 425 Gene3D G3DSA:1.10.287.1060 1 102 2.4E-5 T 28-03-2018 CU254_RS09020 14bc457b0e231b4e2fee3962e1958b85 425 SUPERFAMILY SSF53474 196 349 4.77E-5 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS09020 14bc457b0e231b4e2fee3962e1958b85 425 Pfam PF06259 Alpha/beta hydrolase 175 343 3.6E-16 T 28-03-2018 IPR010427 Protein of unknown function DUF1023 CU254_RS13735 3ae68087a3e25d96d22222f2b56097ff 403 Gene3D G3DSA:2.30.30.410 309 400 5.8E-6 T 28-03-2018 CU254_RS01530 5de70c8fd3d9470d334b810a384b572b 512 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 343 484 1.9E-12 T 28-03-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain CU254_RS01530 5de70c8fd3d9470d334b810a384b572b 512 Pfam PF13440 Polysaccharide biosynthesis protein 51 342 3.2E-69 T 28-03-2018 CU254_RS30745 b496bf05cd6877e866da5d0181ff2bc5 124 Pfam PF05331 Protein of unknown function (DUF742) 13 124 6.8E-33 T 28-03-2018 IPR007995 Protein of unknown function DUF742 CU254_RS30745 b496bf05cd6877e866da5d0181ff2bc5 124 Gene3D G3DSA:1.10.10.10 3 113 3.0E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS37530 424c2b8a1ca36bf4c0adecb76ce893af 314 Pfam PF06089 L-asparaginase II 8 308 3.7E-116 T 28-03-2018 IPR010349 L-asparaginase II CU254_RS36340 16c4448918b384e21b1349f20697f8d1 267 Pfam PF14011 EspG family 11 252 4.0E-64 T 28-03-2018 IPR025734 EspG family CU254_RS06320 bd1e832b9d152d6e63e8cd227f5188cd 149 PRINTS PR01438 Universal stress protein signature 125 147 1.9E-16 T 28-03-2018 IPR006015 Universal stress protein A CU254_RS06320 bd1e832b9d152d6e63e8cd227f5188cd 149 PRINTS PR01438 Universal stress protein signature 4 22 1.9E-16 T 28-03-2018 IPR006015 Universal stress protein A CU254_RS06320 bd1e832b9d152d6e63e8cd227f5188cd 149 PRINTS PR01438 Universal stress protein signature 107 119 1.9E-16 T 28-03-2018 IPR006015 Universal stress protein A CU254_RS06320 bd1e832b9d152d6e63e8cd227f5188cd 149 Gene3D G3DSA:3.40.50.620 2 149 2.6E-32 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS06320 bd1e832b9d152d6e63e8cd227f5188cd 149 SUPERFAMILY SSF52402 3 147 5.19E-29 T 28-03-2018 CU254_RS06320 bd1e832b9d152d6e63e8cd227f5188cd 149 Pfam PF00582 Universal stress protein family 4 147 2.1E-27 T 28-03-2018 IPR006016 UspA GO:0006950 CU254_RS13050 a19886a840b81157a64cfefe3f6da924 150 Gene3D G3DSA:3.10.129.10 1 150 1.3E-36 T 28-03-2018 CU254_RS13050 a19886a840b81157a64cfefe3f6da924 150 Pfam PF01575 MaoC like domain 12 122 7.9E-28 T 28-03-2018 IPR002539 MaoC-like domain CU254_RS13050 a19886a840b81157a64cfefe3f6da924 150 SUPERFAMILY SSF54637 7 146 7.08E-40 T 28-03-2018 IPR029069 HotDog domain CU254_RS38505 247ce9b8b3a9b64b2984b3981ed9a5a4 201 Pfam PF12079 Protein of unknown function (DUF3558) 17 193 2.6E-27 T 28-03-2018 IPR024520 Protein of unknown function DUF3558 CU254_RS38505 247ce9b8b3a9b64b2984b3981ed9a5a4 201 Gene3D G3DSA:3.40.190.10 1 193 4.6E-5 T 28-03-2018 CU254_RS06395 24af308b8094b03d05d406840f5b6528 570 Pfam PF00474 Sodium:solute symporter family 31 199 9.6E-26 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CU254_RS06395 24af308b8094b03d05d406840f5b6528 570 Pfam PF00474 Sodium:solute symporter family 298 484 8.7E-13 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CU254_RS40745 4d4cbaf764ce2c16381a3f26e799c11e 219 Pfam PF07510 Protein of unknown function (DUF1524) 114 211 1.1E-8 T 28-03-2018 IPR011089 Domain of unknown function DUF1524 CU254_RS33885 d18d3305c3c8116b47fd2dd4567f11c7 158 Gene3D G3DSA:1.10.357.10 26 157 3.5E-9 T 28-03-2018 CU254_RS33885 d18d3305c3c8116b47fd2dd4567f11c7 158 Gene3D G3DSA:1.10.10.60 1 25 1.8E-6 T 28-03-2018 CU254_RS33885 d18d3305c3c8116b47fd2dd4567f11c7 158 SUPERFAMILY SSF46689 1 40 4.85E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS05795 8ac9a9de49a797bd193679f1de325f66 298 Pfam PF13460 NAD(P)H-binding 7 191 4.4E-19 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS05795 8ac9a9de49a797bd193679f1de325f66 298 Gene3D G3DSA:3.40.50.720 1 296 8.8E-33 T 28-03-2018 CU254_RS05795 8ac9a9de49a797bd193679f1de325f66 298 SUPERFAMILY SSF51735 1 277 7.39E-52 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS24295 28e2c0b153c927bf438c99d85cefaeae 186 SUPERFAMILY SSF52218 5 182 1.11E-41 T 28-03-2018 IPR029039 Flavoprotein-like domain CU254_RS24295 28e2c0b153c927bf438c99d85cefaeae 186 Pfam PF03358 NADPH-dependent FMN reductase 7 140 2.2E-39 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CU254_RS24295 28e2c0b153c927bf438c99d85cefaeae 186 Gene3D G3DSA:3.40.50.360 1 184 3.7E-44 T 28-03-2018 IPR029039 Flavoprotein-like domain CU254_RS25780 e7d61c7f77820a1852b382d2689c4d83 88 Pfam PF05121 Gas vesicle protein K 4 88 4.2E-32 T 28-03-2018 IPR007805 Gas vesicle protein GvpK GO:0031412 CU254_RS10005 ee658a4a32e91bd62206d45f5418df9b 364 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 5.6E-19 T 28-03-2018 CU254_RS10005 ee658a4a32e91bd62206d45f5418df9b 364 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 291 307 5.6E-19 T 28-03-2018 CU254_RS10005 ee658a4a32e91bd62206d45f5418df9b 364 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 141 156 5.6E-19 T 28-03-2018 CU254_RS10005 ee658a4a32e91bd62206d45f5418df9b 364 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 276 291 5.6E-19 T 28-03-2018 CU254_RS10005 ee658a4a32e91bd62206d45f5418df9b 364 SUPERFAMILY SSF51905 263 340 4.96E-49 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS10005 ee658a4a32e91bd62206d45f5418df9b 364 SUPERFAMILY SSF51905 1 162 4.96E-49 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS10005 ee658a4a32e91bd62206d45f5418df9b 364 Pfam PF01494 FAD binding domain 2 338 8.5E-19 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CU254_RS10005 ee658a4a32e91bd62206d45f5418df9b 364 Gene3D G3DSA:3.50.50.60 1 343 4.8E-39 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CU254_RS24830 452e11701357c9f2abc6285654e88c2c 289 Pfam PF13349 Putative adhesin 103 258 3.3E-8 T 28-03-2018 IPR025164 Putative adhesin CU254_RS14310 e9ca490148f2b4fd093c27160b17d37c 309 Gene3D G3DSA:1.10.260.40 17 98 0.0021 T 28-03-2018 CU254_RS28780 f00910a1f424b682dbe2cf6e7a883a7d 55 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 18 47 0.0015 T 28-03-2018 CU254_RS28780 f00910a1f424b682dbe2cf6e7a883a7d 55 Gene3D G3DSA:1.20.1250.20 4 55 2.2E-4 T 28-03-2018 CU254_RS17735 c8cd89c9088573dc6baa42b86389a293 269 SUPERFAMILY SSF103481 176 260 7.32E-8 T 28-03-2018 CU254_RS17735 c8cd89c9088573dc6baa42b86389a293 269 Pfam PF00892 EamA-like transporter family 125 252 2.1E-14 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CU254_RS17735 c8cd89c9088573dc6baa42b86389a293 269 SUPERFAMILY SSF103481 26 114 3.79E-5 T 28-03-2018 CU254_RS40700 f2ec8c98c183e750576050fd212485dc 373 Pfam PF07730 Histidine kinase 182 248 5.6E-15 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CU254_RS40700 f2ec8c98c183e750576050fd212485dc 373 Gene3D G3DSA:3.30.565.10 241 373 8.3E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS15050 cabd7e4c220e8e9aad4b1697eeee9107 88 Pfam PF04226 Transglycosylase associated protein 33 82 3.7E-8 T 28-03-2018 IPR007341 Transglycosylase-associated protein GO:0016021 CU254_RS40485 ba81b5e6e50fe7a87af5ba2ba73d5222 93 Pfam PF10041 Uncharacterized conserved protein (DUF2277) 1 84 8.5E-34 T 28-03-2018 IPR018735 Protein of unknown function DUF2277 CU254_RS17705 804aa83e6fd771f46f966092945352c0 274 SUPERFAMILY SSF161098 73 259 1.96E-25 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS17705 804aa83e6fd771f46f966092945352c0 274 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 271 2.5E-26 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS17705 804aa83e6fd771f46f966092945352c0 274 Gene3D G3DSA:1.10.3720.10 6 267 2.7E-40 T 28-03-2018 CU254_RS14740 7f9137cd8c3b9daa84d39058b02bba15 134 ProDom PD034138 GP2 GENE GP5 1 130 2.0E-10 T 28-03-2018 IPR020289 Protein of unknown function Gp5 CU254_RS25610 48c810b2f3fc9f2efc092037d53f2636 243 Gene3D G3DSA:3.60.15.10 5 232 1.7E-16 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS25610 48c810b2f3fc9f2efc092037d53f2636 243 SUPERFAMILY SSF56281 34 204 1.6E-23 T 28-03-2018 IPR001279 Metallo-beta-lactamase CU254_RS38995 53c8e173b4e26069616c4429c0ec811b 179 Gene3D G3DSA:3.30.70.1060 1 94 5.3E-17 T 28-03-2018 CU254_RS38995 53c8e173b4e26069616c4429c0ec811b 179 Pfam PF03795 YCII-related domain 2 85 5.1E-15 T 28-03-2018 IPR005545 YCII-related CU254_RS38995 53c8e173b4e26069616c4429c0ec811b 179 SUPERFAMILY SSF54909 2 86 4.02E-14 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS38995 53c8e173b4e26069616c4429c0ec811b 179 Gene3D G3DSA:3.30.70.1060 119 175 0.033 T 28-03-2018 CU254_RS23370 ccda88cdc335823af803a147417ec832 139 Gene3D G3DSA:3.30.750.24 17 128 5.1E-14 T 28-03-2018 IPR002645 STAS domain CU254_RS23370 ccda88cdc335823af803a147417ec832 139 SUPERFAMILY SSF52091 24 122 1.08E-13 T 28-03-2018 IPR002645 STAS domain CU254_RS23370 ccda88cdc335823af803a147417ec832 139 Pfam PF13466 STAS domain 32 112 5.0E-10 T 28-03-2018 IPR002645 STAS domain CU254_RS41140 89575ec0ca340a5ff65f57f66a16788b 411 Gene3D G3DSA:1.10.287.850 7 104 1.5E-7 T 28-03-2018 CU254_RS01220 9dd192dfe69d10fd6b3292efe9f3ce9d 257 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 21 235 4.8E-40 T 28-03-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 CU254_RS30925 ebd567c7642ff3118d23c1685fc30eac 192 Pfam PF01872 RibD C-terminal domain 86 169 1.0E-7 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CU254_RS30925 ebd567c7642ff3118d23c1685fc30eac 192 SUPERFAMILY SSF53597 3 191 9.68E-18 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CU254_RS30925 ebd567c7642ff3118d23c1685fc30eac 192 Gene3D G3DSA:3.40.430.10 2 192 1.3E-30 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CU254_RS38605 a924ef211730f87335e24897fdebfcac 155 Pfam PF04186 FxsA cytoplasmic membrane protein 4 110 1.7E-33 T 28-03-2018 IPR007313 FxsA cytoplasmic membrane protein GO:0016020 CU254_RS38960 48fb6a191d5b1c3fa16d6ee01587bf12 112 Gene3D G3DSA:1.10.287.1060 8 108 0.0011 T 28-03-2018 CU254_RS36290 7b23444f7a9de9b2932a360b5ecc6d9d 368 Pfam PF13367 Protease prsW family 58 255 2.5E-52 T 28-03-2018 IPR026898 Protease PrsW GO:0008233 CU254_RS15490 31555f175bf1d0ec620830f2b6b431a5 111 Pfam PF11239 Protein of unknown function (DUF3040) 11 83 2.2E-6 T 28-03-2018 IPR021401 Protein of unknown function DUF3040 CU254_RS29710 4cc08f32f424416cfd2c04b8ee365df0 198 Gene3D G3DSA:3.40.50.1000 75 189 1.1E-5 T 28-03-2018 IPR023214 HAD-like domain CU254_RS29710 4cc08f32f424416cfd2c04b8ee365df0 198 Pfam PF03767 HAD superfamily, subfamily IIIB (Acid phosphatase) 102 193 2.8E-7 T 28-03-2018 IPR005519 Acid phosphatase, class B-like CU254_RS21590 321432ad925cb14ea1f52174a8818c5f 231 Pfam PF03591 AzlC protein 19 155 3.7E-35 T 28-03-2018 IPR011606 Branched-chain amino acid transport, permease CU254_RS34615 bef6d9136fc1f1e0cf6e82277fed5c95 264 SUPERFAMILY SSF160920 8 256 9.81E-111 T 28-03-2018 CU254_RS34615 bef6d9136fc1f1e0cf6e82277fed5c95 264 Hamap MF_01830 UPF0317 protein . 11 263 51.91 T 28-03-2018 IPR016938 Uncharacterised protein family UPF0317 CU254_RS34615 bef6d9136fc1f1e0cf6e82277fed5c95 264 PIRSF PIRSF029755 1 264 1.8E-115 T 28-03-2018 IPR016938 Uncharacterised protein family UPF0317 CU254_RS34615 bef6d9136fc1f1e0cf6e82277fed5c95 264 Pfam PF07286 Protein of unknown function (DUF1445) 113 255 3.4E-66 T 28-03-2018 IPR009906 D-glutamate cyclase CU254_RS34615 bef6d9136fc1f1e0cf6e82277fed5c95 264 Gene3D G3DSA:3.40.1640.10 1 164 6.4E-64 T 28-03-2018 CU254_RS34615 bef6d9136fc1f1e0cf6e82277fed5c95 264 Gene3D G3DSA:3.40.1640.10 200 263 8.9E-10 T 28-03-2018 CU254_RS33150 2026a134000c5e2282f42fe8d0a562f0 454 PIRSF PIRSF002744 2 453 4.6E-113 T 28-03-2018 IPR026030 Purine-cytosine permease Fcy2/21/22 GO:0005215|GO:0016021|GO:0055085 CU254_RS33150 2026a134000c5e2282f42fe8d0a562f0 454 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 12 434 1.8E-55 T 28-03-2018 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 CU254_RS05540 bc623b9800bc90f2fef2f2ac0a464da7 312 SUPERFAMILY SSF51445 75 307 1.66E-16 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS05540 bc623b9800bc90f2fef2f2ac0a464da7 312 Gene3D G3DSA:3.20.20.80 21 309 1.0E-18 T 28-03-2018 CU254_RS14970 4bb7b49f652893205642ec19c244bbcf 311 SUPERFAMILY SSF161098 34 296 1.18E-46 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS14970 4bb7b49f652893205642ec19c244bbcf 311 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 124 295 7.3E-6 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CU254_RS14970 4bb7b49f652893205642ec19c244bbcf 311 Gene3D G3DSA:1.10.3720.10 38 303 1.0E-35 T 28-03-2018 CU254_RS33100 a7896efef5a5f674cf9e3a43d0445de0 356 SUPERFAMILY SSF53474 25 63 1.01E-22 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS33100 a7896efef5a5f674cf9e3a43d0445de0 356 SUPERFAMILY SSF53474 110 308 1.01E-22 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS33100 a7896efef5a5f674cf9e3a43d0445de0 356 Pfam PF03403 Platelet-activating factor acetylhydrolase, isoform II 197 348 5.0E-6 T 28-03-2018 IPR005065 Platelet-activating factor acetylhydrolase-like GO:0003847|GO:0016042 KEGG: 00565+3.1.1.47 CU254_RS33100 a7896efef5a5f674cf9e3a43d0445de0 356 Pfam PF03403 Platelet-activating factor acetylhydrolase, isoform II 24 152 7.9E-10 T 28-03-2018 IPR005065 Platelet-activating factor acetylhydrolase-like GO:0003847|GO:0016042 KEGG: 00565+3.1.1.47 CU254_RS33100 a7896efef5a5f674cf9e3a43d0445de0 356 Gene3D G3DSA:3.40.50.1820 18 356 3.7E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS42005 bb2960d32ca51455f90a36fcbed35394 426 Gene3D G3DSA:1.20.5.320 109 211 2.6E-4 T 28-03-2018 CU254_RS17690 a87cb7af51d6cf36c55d31583c25f5e9 340 SUPERFAMILY SSF51679 14 328 1.96E-48 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS17690 a87cb7af51d6cf36c55d31583c25f5e9 340 Pfam PF00296 Luciferase-like monooxygenase 29 261 2.2E-27 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CU254_RS17690 a87cb7af51d6cf36c55d31583c25f5e9 340 Gene3D G3DSA:3.20.20.30 3 335 4.1E-51 T 28-03-2018 CU254_RS34345 6a6f1a0424555758319ea4610b8c1f7a 539 Pfam PF01566 Natural resistance-associated macrophage protein 70 423 7.1E-78 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CU254_RS06800 0b2e8f0af7bdc2942a1ab76cbc09c04e 218 SUPERFAMILY SSF55021 4 71 5.41E-7 T 28-03-2018 CU254_RS06800 0b2e8f0af7bdc2942a1ab76cbc09c04e 218 Gene3D G3DSA:3.30.70.260 2 75 4.3E-9 T 28-03-2018 CU254_RS26185 65855b550e43040f48385fe7ca420a62 122 Gene3D G3DSA:1.10.287.1060 1 102 1.9E-8 T 28-03-2018 CU254_RS13520 8d8117d0093985645fd4cf0fa944ed30 183 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 78 158 1.1E-5 T 28-03-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 CU254_RS13520 8d8117d0093985645fd4cf0fa944ed30 183 Gene3D G3DSA:3.30.1380.10 38 164 1.6E-10 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CU254_RS13520 8d8117d0093985645fd4cf0fa944ed30 183 SUPERFAMILY SSF55166 48 161 9.42E-15 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CU254_RS26420 02c7051e5a35f407063bf39e1dbafa1f 149 Pfam PF10825 Protein of unknown function (DUF2752) 52 98 2.6E-18 T 28-03-2018 IPR021215 Protein of unknown function DUF2752 CU254_RS19120 0d69a23fb1ad3c18d3d548f69167b381 107 SUPERFAMILY SSF54909 1 105 3.75E-32 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CU254_RS19120 0d69a23fb1ad3c18d3d548f69167b381 107 Pfam PF03795 YCII-related domain 1 105 8.3E-19 T 28-03-2018 IPR005545 YCII-related CU254_RS19120 0d69a23fb1ad3c18d3d548f69167b381 107 Gene3D G3DSA:3.30.70.1060 1 107 5.6E-37 T 28-03-2018 CU254_RS34895 1996573b9486480bab62732fac3de085 476 PIRSF PIRSF006060 1 471 1.2E-64 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CU254_RS34895 1996573b9486480bab62732fac3de085 476 ProSitePatterns PS00218 Amino acid permeases signature. 43 73 - T 28-03-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 CU254_RS34895 1996573b9486480bab62732fac3de085 476 Pfam PF00324 Amino acid permease 19 447 6.3E-95 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CU254_RS25190 bd98ae5ffeff7bde586a7500c556b441 76 Pfam PF05108 Type VII secretion system ESX-1, transport TM domain B 4 63 3.8E-14 T 28-03-2018 IPR007795 Type VII secretion system EccB CU254_RS22335 7e7c57b347a61754c9ff58f729be9050 475 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 28 457 1.6E-92 T 28-03-2018 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 CU254_RS22895 931b5fe6e839ec4f7e96a3ff227fe695 381 Pfam PF02653 Branched-chain amino acid transport system / permease component 68 334 1.6E-47 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CU254_RS22895 931b5fe6e839ec4f7e96a3ff227fe695 381 Gene3D G3DSA:1.10.3470.10 63 339 8.0E-45 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CU254_RS30710 4cf83e91437e26f554e5023ec21df6e3 137 Pfam PF09350 Domain of unknown function (DUF1992) 14 83 4.6E-15 T 28-03-2018 IPR018961 DnaJ homologue, subfamily C, member 28, conserved domain CU254_RS06425 ee53fc5d7c8909a282bd587e38485497 254 Gene3D G3DSA:3.40.50.300 2 252 3.6E-49 T 28-03-2018 CU254_RS06425 ee53fc5d7c8909a282bd587e38485497 254 SUPERFAMILY SSF52540 5 229 4.52E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS06425 ee53fc5d7c8909a282bd587e38485497 254 Pfam PF00005 ABC transporter 22 177 7.4E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CU254_RS06425 ee53fc5d7c8909a282bd587e38485497 254 SMART SM00382 30 225 1.7E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CU254_RS15820 9ff040078dcbc86a58c64583e6afb336 284 SUPERFAMILY SSF53448 4 227 5.44E-42 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS15820 9ff040078dcbc86a58c64583e6afb336 284 Gene3D G3DSA:3.90.550.10 2 249 1.3E-38 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS15820 9ff040078dcbc86a58c64583e6afb336 284 Pfam PF00535 Glycosyl transferase family 2 5 120 3.0E-20 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CU254_RS08610 b72745b37cd5f6244e32165f6fda40cf 144 Pfam PF11253 Protein of unknown function (DUF3052) 13 137 3.6E-55 T 28-03-2018 IPR021412 Protein of unknown function DUF3052 CU254_RS18850 fdc3b714332fca2a308ada0230026e94 229 Gene3D G3DSA:3.40.50.1820 8 216 1.2E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS18850 fdc3b714332fca2a308ada0230026e94 229 Pfam PF12697 Alpha/beta hydrolase family 27 208 9.7E-13 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS18850 fdc3b714332fca2a308ada0230026e94 229 SUPERFAMILY SSF53474 2 214 7.74E-34 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS05125 44063e7cbe914917f4532cfcdcc08fca 190 SUPERFAMILY SSF82607 2 82 3.4E-12 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CU254_RS05125 44063e7cbe914917f4532cfcdcc08fca 190 Gene3D G3DSA:3.30.1310.10 1 97 3.8E-20 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CU254_RS05125 44063e7cbe914917f4532cfcdcc08fca 190 Pfam PF02575 YbaB/EbfC DNA-binding family 2 84 5.6E-14 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CU254_RS19215 58e618ed762fd745d450baf2bbeefd9d 266 SUPERFAMILY SSF141571 54 87 2.94E-21 T 28-03-2018 CU254_RS19215 58e618ed762fd745d450baf2bbeefd9d 266 SUPERFAMILY SSF141571 133 258 2.94E-21 T 28-03-2018 CU254_RS19215 58e618ed762fd745d450baf2bbeefd9d 266 Pfam PF00805 Pentapeptide repeats (8 copies) 197 236 1.1E-13 T 28-03-2018 IPR001646 Pentapeptide repeat CU254_RS19215 58e618ed762fd745d450baf2bbeefd9d 266 Gene3D G3DSA:2.160.20.80 41 258 1.3E-26 T 28-03-2018 CU254_RS20800 02e450444e3bd82bb89aeebf508eab66 529 Pfam PF02538 Hydantoinase B/oxoprolinase 5 524 1.9E-157 T 28-03-2018 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403 CU254_RS37170 777afd7dfaab8c0c113c012cfd00435f 226 Gene3D G3DSA:1.10.10.60 1 62 4.1E-15 T 28-03-2018 CU254_RS37170 777afd7dfaab8c0c113c012cfd00435f 226 Gene3D G3DSA:1.10.357.10 63 224 6.5E-36 T 28-03-2018 CU254_RS37170 777afd7dfaab8c0c113c012cfd00435f 226 SUPERFAMILY SSF46689 9 80 2.23E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS37170 777afd7dfaab8c0c113c012cfd00435f 226 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 66 3.8E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS37170 777afd7dfaab8c0c113c012cfd00435f 226 SUPERFAMILY SSF48498 90 221 2.22E-31 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS27340 c18ce1b021f421d2af737e3acf2a78b6 230 Gene3D G3DSA:1.10.1530.10 16 81 6.6E-4 T 28-03-2018 CU254_RS16965 66eb8c43665c310527e20e771c403cc1 301 Gene3D G3DSA:3.40.50.150 59 248 1.6E-16 T 28-03-2018 CU254_RS16965 66eb8c43665c310527e20e771c403cc1 301 Pfam PF13649 Methyltransferase domain 103 190 1.2E-11 T 28-03-2018 CU254_RS16965 66eb8c43665c310527e20e771c403cc1 301 SUPERFAMILY SSF53335 82 191 9.73E-18 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS29725 2e1701a5d1b899b922469cd294c1ffd6 120 Pfam PF17240 Family of unknown function (DUF5313) 2 114 7.7E-24 T 28-03-2018 IPR035197 Protein of unknown function DUF5313 CU254_RS10615 020f598cdceba632914751c874a06ab3 405 Pfam PF13520 Amino acid permease 7 377 8.4E-44 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CU254_RS10615 020f598cdceba632914751c874a06ab3 405 PIRSF PIRSF006060 1 398 2.5E-68 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CU254_RS07755 334e0ee26fdcfe23044067ad14211841 521 Pfam PF00474 Sodium:solute symporter family 33 441 1.8E-32 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CU254_RS22990 bb793f87c11c65b9887a47209f39db08 239 Pfam PF02308 MgtC family 18 143 9.9E-36 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CU254_RS22990 bb793f87c11c65b9887a47209f39db08 239 PRINTS PR01837 MgtC/SapB protein signature 39 57 2.7E-43 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CU254_RS22990 bb793f87c11c65b9887a47209f39db08 239 PRINTS PR01837 MgtC/SapB protein signature 100 124 2.7E-43 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CU254_RS22990 bb793f87c11c65b9887a47209f39db08 239 PRINTS PR01837 MgtC/SapB protein signature 20 39 2.7E-43 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CU254_RS22990 bb793f87c11c65b9887a47209f39db08 239 PRINTS PR01837 MgtC/SapB protein signature 73 95 2.7E-43 T 28-03-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 CU254_RS18085 83b3a9b98e953f5004895311e7c6f21f 265 ProDom PD040491 SCO1799 RV1486C/MT1533 MB1522C CGL1536 ML1804 MAV321 4 214 5.0E-13 T 28-03-2018 CU254_RS03795 b280fd0fd55d47b173e92f1046a55b7f 165 Pfam PF06210 Protein of unknown function (DUF1003) 40 140 2.4E-39 T 28-03-2018 IPR010406 Protein of unknown function DUF1003 CU254_RS35845 6c31411a4047a932b47214bdbd80b230 168 Gene3D G3DSA:2.30.110.10 4 167 1.1E-36 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS35845 6c31411a4047a932b47214bdbd80b230 168 SUPERFAMILY SSF50475 10 163 1.39E-44 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS35845 6c31411a4047a932b47214bdbd80b230 168 Pfam PF01613 Flavin reductase like domain 15 163 1.3E-30 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CU254_RS35845 6c31411a4047a932b47214bdbd80b230 168 SMART SM00903 15 162 7.6E-48 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CU254_RS40465 cda28d025890fbc978ea4a5b8a12a212 310 SUPERFAMILY SSF55486 82 253 7.33E-6 T 28-03-2018 CU254_RS40465 cda28d025890fbc978ea4a5b8a12a212 310 Pfam PF04228 Putative neutral zinc metallopeptidase 11 304 2.1E-75 T 28-03-2018 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative CU254_RS37810 5911e4aca4a720313386ae32338e1536 328 Pfam PF10282 Lactonase, 7-bladed beta-propeller 5 325 3.4E-60 T 28-03-2018 IPR019405 Lactonase, 7-bladed beta propeller CU254_RS37810 5911e4aca4a720313386ae32338e1536 328 Gene3D G3DSA:2.130.10.10 127 326 1.5E-9 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CU254_RS37810 5911e4aca4a720313386ae32338e1536 328 Gene3D G3DSA:2.130.10.10 7 126 6.3E-12 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CU254_RS37810 5911e4aca4a720313386ae32338e1536 328 SUPERFAMILY SSF51004 14 316 1.15E-24 T 28-03-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain CU254_RS21765 2d45e9684cc23913c9df8b10dba2751d 403 SUPERFAMILY SSF48264 15 403 2.88E-94 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS21765 2d45e9684cc23913c9df8b10dba2751d 403 Pfam PF00067 Cytochrome P450 169 371 1.5E-21 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CU254_RS21765 2d45e9684cc23913c9df8b10dba2751d 403 Gene3D G3DSA:1.10.630.10 7 403 5.6E-81 T 28-03-2018 CU254_RS21765 2d45e9684cc23913c9df8b10dba2751d 403 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 343 352 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CU254_RS21765 2d45e9684cc23913c9df8b10dba2751d 403 PRINTS PR00359 B-class P450 signature 192 214 6.6E-46 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS21765 2d45e9684cc23913c9df8b10dba2751d 403 PRINTS PR00359 B-class P450 signature 274 285 6.6E-46 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS21765 2d45e9684cc23913c9df8b10dba2751d 403 PRINTS PR00359 B-class P450 signature 157 172 6.6E-46 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS21765 2d45e9684cc23913c9df8b10dba2751d 403 PRINTS PR00359 B-class P450 signature 341 350 6.6E-46 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS21765 2d45e9684cc23913c9df8b10dba2751d 403 PRINTS PR00359 B-class P450 signature 320 335 6.6E-46 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS21765 2d45e9684cc23913c9df8b10dba2751d 403 PRINTS PR00359 B-class P450 signature 350 361 6.6E-46 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS21765 2d45e9684cc23913c9df8b10dba2751d 403 PRINTS PR00359 B-class P450 signature 94 105 6.6E-46 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS21765 2d45e9684cc23913c9df8b10dba2751d 403 PRINTS PR00359 B-class P450 signature 292 319 6.6E-46 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS21765 2d45e9684cc23913c9df8b10dba2751d 403 PRINTS PR00359 B-class P450 signature 140 156 6.6E-46 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CU254_RS41905 76dde3f97bf2f9de33ac5d493b380203 347 Gene3D G3DSA:3.40.50.620 7 332 7.0E-15 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS41905 76dde3f97bf2f9de33ac5d493b380203 347 SUPERFAMILY SSF52402 29 227 7.99E-10 T 28-03-2018 CU254_RS14625 ea7b18790560248186d5a94162f20775 367 Gene3D G3DSA:2.130.10.10 7 367 6.5E-64 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CU254_RS14625 ea7b18790560248186d5a94162f20775 367 Pfam PF02012 BNR/Asp-box repeat 124 134 0.08 T 28-03-2018 IPR002860 BNR repeat CU254_RS14625 ea7b18790560248186d5a94162f20775 367 Pfam PF02012 BNR/Asp-box repeat 61 71 0.07 T 28-03-2018 IPR002860 BNR repeat CU254_RS14625 ea7b18790560248186d5a94162f20775 367 SUPERFAMILY SSF110296 12 364 1.57E-67 T 28-03-2018 CU254_RS23250 8964b0cc517fa08b7410a2b08c16a769 328 Gene3D G3DSA:3.20.20.100 1 325 2.2E-98 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS23250 8964b0cc517fa08b7410a2b08c16a769 328 Pfam PF00248 Aldo/keto reductase family 15 309 2.6E-73 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS23250 8964b0cc517fa08b7410a2b08c16a769 328 SUPERFAMILY SSF51430 4 310 4.58E-97 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS14675 16136d02dc3a4a3e8793603d65b1a774 282 Gene3D G3DSA:2.60.120.260 84 240 1.1E-5 T 28-03-2018 IPR008979 Galactose-binding domain-like CU254_RS25575 8916a27e57e51e4d0fde5b32b6f949aa 491 Pfam PF00474 Sodium:solute symporter family 34 395 5.5E-9 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CU254_RS38535 bf30daa69e996c71bbe6360b7053f610 553 Pfam PF14403 Circularly permuted ATP-grasp type 2 110 486 4.6E-160 T 28-03-2018 IPR025841 Circularly permuted ATP-grasp type 2 CU254_RS38535 bf30daa69e996c71bbe6360b7053f610 553 PIRSF PIRSF005522 36 513 6.3E-215 T 28-03-2018 IPR016450 Uncharacterised conserved protein UCP005522 CU254_RS38535 bf30daa69e996c71bbe6360b7053f610 553 SUPERFAMILY SSF56059 57 248 1.3E-58 T 28-03-2018 CU254_RS38535 bf30daa69e996c71bbe6360b7053f610 553 SUPERFAMILY SSF56059 355 501 1.3E-58 T 28-03-2018 CU254_RS38535 bf30daa69e996c71bbe6360b7053f610 553 Gene3D G3DSA:3.30.470.20 368 521 4.4E-5 T 28-03-2018 CU254_RS05525 8a1da07c7d9ff076f209e40b4e365de0 108 Gene3D G3DSA:1.10.287.1060 1 103 9.5E-5 T 28-03-2018 CU254_RS28425 3a4d7df6ccd3dfc7b430518877578372 409 Gene3D G3DSA:3.90.79.10 204 376 3.0E-4 T 28-03-2018 CU254_RS17530 6b455a1524a0cdbd7a9c0f78b3dc3a7f 132 SUPERFAMILY SSF54427 11 122 3.32E-13 T 28-03-2018 IPR032710 NTF2-like domain CU254_RS17530 6b455a1524a0cdbd7a9c0f78b3dc3a7f 132 Gene3D G3DSA:3.10.450.50 6 128 1.8E-12 T 28-03-2018 CU254_RS17530 6b455a1524a0cdbd7a9c0f78b3dc3a7f 132 Pfam PF12680 SnoaL-like domain 13 114 1.3E-6 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CU254_RS40340 70f02f8bd34eadffd2638b017797b5fa 236 Pfam PF14011 EspG family 14 229 6.8E-32 T 28-03-2018 IPR025734 EspG family CU254_RS39085 ff757ba0d67d2cae6d2c5824cec39e35 139 Pfam PF13630 SdpI/YhfL protein family 30 92 1.8E-9 T 28-03-2018 IPR025962 SdpI/YhfL protein family CU254_RS37250 8048709379412f852bf0bbf67d8807ec 916 Pfam PF01580 FtsK/SpoIIIE family 393 566 1.0E-19 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CU254_RS37250 8048709379412f852bf0bbf67d8807ec 916 Gene3D G3DSA:3.40.50.300 320 603 1.7E-19 T 28-03-2018 CU254_RS37250 8048709379412f852bf0bbf67d8807ec 916 SUPERFAMILY SSF52540 382 592 7.5E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS40330 bd5fb45b4d4e52e0014f37218e686172 348 Pfam PF01040 UbiA prenyltransferase family 90 320 6.6E-18 T 28-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 CU254_RS02145 85b05e9e68fdda3a08a91403ac06aa7c 102 Gene3D G3DSA:1.10.287.1060 1 97 1.7E-5 T 28-03-2018 CU254_RS22345 ba68b89ac0f6c775564a0eda65767fb1 380 Pfam PF01757 Acyltransferase family 24 354 1.4E-18 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CU254_RS22625 470adbf81852023d2432fc63592a625d 235 Gene3D G3DSA:3.30.420.10 1 234 3.7E-6 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS22625 470adbf81852023d2432fc63592a625d 235 SUPERFAMILY SSF53098 9 104 1.06E-9 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CU254_RS39145 f30c3f0b8a5a3b1ff87f0c8f7ca624e8 619 Pfam PF03023 MviN-like protein 121 564 7.3E-86 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CU254_RS39145 f30c3f0b8a5a3b1ff87f0c8f7ca624e8 619 PRINTS PR01806 Virulence factor MviN signature 221 245 4.2E-25 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CU254_RS39145 f30c3f0b8a5a3b1ff87f0c8f7ca624e8 619 PRINTS PR01806 Virulence factor MviN signature 245 266 4.2E-25 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CU254_RS39145 f30c3f0b8a5a3b1ff87f0c8f7ca624e8 619 PRINTS PR01806 Virulence factor MviN signature 125 144 4.2E-25 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CU254_RS39145 f30c3f0b8a5a3b1ff87f0c8f7ca624e8 619 PRINTS PR01806 Virulence factor MviN signature 455 474 4.2E-25 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CU254_RS39145 f30c3f0b8a5a3b1ff87f0c8f7ca624e8 619 PRINTS PR01806 Virulence factor MviN signature 357 383 4.2E-25 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CU254_RS39145 f30c3f0b8a5a3b1ff87f0c8f7ca624e8 619 PRINTS PR01806 Virulence factor MviN signature 144 160 4.2E-25 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CU254_RS39145 f30c3f0b8a5a3b1ff87f0c8f7ca624e8 619 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 94 607 1.2E-79 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CU254_RS15020 575efaa3093a4939e7f932e3154e68bd 191 Gene3D G3DSA:1.20.1260.10 32 191 9.3E-56 T 28-03-2018 IPR012347 Ferritin-related CU254_RS15020 575efaa3093a4939e7f932e3154e68bd 191 Pfam PF03713 Domain of unknown function (DUF305) 40 188 2.9E-54 T 28-03-2018 IPR005183 Domain of unknown function DUF305 CU254_RS19125 134e76ec5fb56e02f489041ad5ca109a 162 SMART SM00871 1 161 2.4E-10 T 28-03-2018 IPR010499 Bacterial transcription activator, effector binding CU254_RS19125 134e76ec5fb56e02f489041ad5ca109a 162 SUPERFAMILY SSF55136 3 158 9.59E-12 T 28-03-2018 CU254_RS19125 134e76ec5fb56e02f489041ad5ca109a 162 Pfam PF06445 GyrI-like small molecule binding domain 2 160 2.9E-14 T 28-03-2018 IPR029442 GyrI-like small molecule binding domain CU254_RS19125 134e76ec5fb56e02f489041ad5ca109a 162 Gene3D G3DSA:3.20.80.10 1 162 9.8E-24 T 28-03-2018 IPR011256 Regulatory factor, effector binding domain CU254_RS08515 7a1973f5774d249388d69bd4763dd54d 242 Gene3D G3DSA:3.30.930.10 5 231 3.8E-47 T 28-03-2018 CU254_RS08515 7a1973f5774d249388d69bd4763dd54d 242 Pfam PF03099 Biotin/lipoate A/B protein ligase family 54 153 5.5E-5 T 28-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CU254_RS08515 7a1973f5774d249388d69bd4763dd54d 242 SUPERFAMILY SSF55681 9 235 1.41E-48 T 28-03-2018 CU254_RS35990 c46f3483047120b897b77ea524a2e1b7 490 SUPERFAMILY SSF53822 95 477 3.36E-19 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CU254_RS35990 c46f3483047120b897b77ea524a2e1b7 490 Gene3D G3DSA:3.40.50.2300 90 467 4.4E-15 T 28-03-2018 CU254_RS27075 62b55443e8e0ace96573936ead3d16ce 161 Pfam PF09900 Predicted membrane protein (DUF2127) 14 153 7.9E-26 T 28-03-2018 IPR021125 Protein of unknown function DUF2127 CU254_RS42650 a6c41ef0940b2473592354b4eb3e57aa 102 Pfam PF05713 Bacterial mobilisation protein (MobC) 40 81 4.0E-5 T 28-03-2018 IPR008687 Bacterial mobilisation CU254_RS13900 3da5cae202e7bd7d4ae692066a2b535f 137 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 3 88 2.2E-13 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CU254_RS13900 3da5cae202e7bd7d4ae692066a2b535f 137 SUPERFAMILY SSF50475 2 130 6.55E-26 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS13900 3da5cae202e7bd7d4ae692066a2b535f 137 Gene3D G3DSA:2.30.110.10 1 136 5.4E-28 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS13900 3da5cae202e7bd7d4ae692066a2b535f 137 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 6 128 9.1E-30 T 28-03-2018 IPR019920 F420-binding domain, putative CU254_RS15145 2750742d6eb38425c873df74ba6156d4 69 Pfam PF09489 Probable cobalt transporter subunit (CbtB) 17 69 3.9E-15 T 28-03-2018 IPR012667 Cobalt transporter subunit CbtB, putative CU254_RS31060 712d95bdcb4ce5a473ce025502f93ccd 590 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 36 480 2.8E-150 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CU254_RS31060 712d95bdcb4ce5a473ce025502f93ccd 590 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 257 311 - T 28-03-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CU254_RS31060 712d95bdcb4ce5a473ce025502f93ccd 590 Gene3D G3DSA:1.20.210.10 23 536 6.7E-200 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CU254_RS31060 712d95bdcb4ce5a473ce025502f93ccd 590 PRINTS PR01165 Cytochrome c oxidase subunit I signature 386 405 4.0E-100 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CU254_RS31060 712d95bdcb4ce5a473ce025502f93ccd 590 PRINTS PR01165 Cytochrome c oxidase subunit I signature 101 125 4.0E-100 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CU254_RS31060 712d95bdcb4ce5a473ce025502f93ccd 590 PRINTS PR01165 Cytochrome c oxidase subunit I signature 323 344 4.0E-100 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CU254_RS31060 712d95bdcb4ce5a473ce025502f93ccd 590 PRINTS PR01165 Cytochrome c oxidase subunit I signature 144 156 4.0E-100 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CU254_RS31060 712d95bdcb4ce5a473ce025502f93ccd 590 PRINTS PR01165 Cytochrome c oxidase subunit I signature 255 276 4.0E-100 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CU254_RS31060 712d95bdcb4ce5a473ce025502f93ccd 590 PRINTS PR01165 Cytochrome c oxidase subunit I signature 205 224 4.0E-100 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CU254_RS31060 712d95bdcb4ce5a473ce025502f93ccd 590 PRINTS PR01165 Cytochrome c oxidase subunit I signature 358 376 4.0E-100 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CU254_RS31060 712d95bdcb4ce5a473ce025502f93ccd 590 PRINTS PR01165 Cytochrome c oxidase subunit I signature 234 255 4.0E-100 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CU254_RS31060 712d95bdcb4ce5a473ce025502f93ccd 590 PRINTS PR01165 Cytochrome c oxidase subunit I signature 176 194 4.0E-100 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CU254_RS31060 712d95bdcb4ce5a473ce025502f93ccd 590 PRINTS PR01165 Cytochrome c oxidase subunit I signature 27 52 4.0E-100 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CU254_RS31060 712d95bdcb4ce5a473ce025502f93ccd 590 PRINTS PR01165 Cytochrome c oxidase subunit I signature 301 316 4.0E-100 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CU254_RS31060 712d95bdcb4ce5a473ce025502f93ccd 590 PRINTS PR01165 Cytochrome c oxidase subunit I signature 74 97 4.0E-100 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CU254_RS31060 712d95bdcb4ce5a473ce025502f93ccd 590 PRINTS PR01165 Cytochrome c oxidase subunit I signature 436 457 4.0E-100 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CU254_RS31060 712d95bdcb4ce5a473ce025502f93ccd 590 SUPERFAMILY SSF81442 25 535 1.57E-178 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CU254_RS31060 712d95bdcb4ce5a473ce025502f93ccd 590 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 30 532 6.6E-218 T 28-03-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 CU254_RS36815 834f3cd967adaa73beda165ab7976c91 53 Pfam PF13783 Domain of unknown function (DUF4177) 6 42 3.3E-6 T 28-03-2018 IPR025234 Protein of unknown function DUF4177 CU254_RS21215 ea318b52769367a10a9bb28ef46dc808 163 Gene3D G3DSA:1.20.120.450 1 39 0.0058 T 28-03-2018 CU254_RS21215 ea318b52769367a10a9bb28ef46dc808 163 Gene3D G3DSA:1.20.120.450 42 161 1.2E-14 T 28-03-2018 CU254_RS21215 ea318b52769367a10a9bb28ef46dc808 163 SUPERFAMILY SSF109854 45 139 4.21E-6 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CU254_RS21215 ea318b52769367a10a9bb28ef46dc808 163 Pfam PF12867 DinB superfamily 5 153 4.7E-17 T 28-03-2018 IPR024775 DinB-like domain CU254_RS00440 219c1cd92ee23677ebba0b963294a59c 65 SUPERFAMILY SSF52540 5 56 1.03E-8 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS00440 219c1cd92ee23677ebba0b963294a59c 65 Gene3D G3DSA:3.40.50.300 2 62 9.7E-9 T 28-03-2018 CU254_RS32540 9a36a1c8297dd446362135b0a98b8e84 514 PIRSF PIRSF006060 8 499 4.3E-90 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CU254_RS32540 9a36a1c8297dd446362135b0a98b8e84 514 Pfam PF13520 Amino acid permease 30 465 1.1E-51 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CU254_RS28910 86617475dae1f3a8c5b808fb824f4e81 142 Pfam PF14145 YrhK-like protein 62 112 1.7E-12 T 28-03-2018 IPR025424 YrhK domain CU254_RS21390 0fd1841186fb4238cb4fd557381fd9e9 114 Gene3D G3DSA:3.30.750.24 8 114 4.4E-10 T 28-03-2018 IPR002645 STAS domain CU254_RS21390 0fd1841186fb4238cb4fd557381fd9e9 114 Pfam PF13466 STAS domain 24 98 7.0E-11 T 28-03-2018 IPR002645 STAS domain CU254_RS21390 0fd1841186fb4238cb4fd557381fd9e9 114 SUPERFAMILY SSF52091 15 99 2.55E-14 T 28-03-2018 IPR002645 STAS domain CU254_RS05110 3a4f12ab9a88af987a7bc71e52a9e014 198 Pfam PF01810 LysE type translocator 16 198 2.6E-14 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CU254_RS05325 64767d40bf925d60ab1f674dc0032457 753 SUPERFAMILY SSF52540 220 306 7.79E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS05325 64767d40bf925d60ab1f674dc0032457 753 SUPERFAMILY SSF52540 487 597 7.79E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS05325 64767d40bf925d60ab1f674dc0032457 753 Gene3D G3DSA:3.40.50.300 206 560 4.1E-7 T 28-03-2018 CU254_RS07280 7c403e2f2091c52c0f4ad48e511d193e 280 Pfam PF02405 Permease MlaE 63 267 1.7E-58 T 28-03-2018 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 CU254_RS04990 b2d3833163ca36dfb1bb6bd3021fc916 252 Pfam PF12730 ABC-2 family transporter protein 6 179 3.0E-8 T 28-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 CU254_RS15150 b11921b5376d66c51bc4b99f1a76a6d3 279 Pfam PF09490 Probable cobalt transporter subunit (CbtA) 4 265 6.1E-73 T 28-03-2018 IPR012666 Cobalt transporter subunit CbtA, putative CU254_RS18480 0c05dddb4b2e11f03a69da4fba9482aa 290 SUPERFAMILY SSF51430 4 275 5.63E-42 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS18480 0c05dddb4b2e11f03a69da4fba9482aa 290 Gene3D G3DSA:3.20.20.100 1 279 1.9E-40 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS18480 0c05dddb4b2e11f03a69da4fba9482aa 290 Pfam PF00248 Aldo/keto reductase family 5 262 5.4E-29 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CU254_RS04950 264a48793d64b679834512d3b1d57e46 376 Pfam PF01384 Phosphate transporter family 21 319 2.8E-81 T 28-03-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 CU254_RS01385 1545d8c4f715c0189780578fcdf72bfb 292 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 36 184 2.9E-33 T 28-03-2018 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CU254_RS26450 74be86e3e3f8748c26a03ac94350695c 348 Pfam PF02562 PhoH-like protein 124 327 1.7E-94 T 28-03-2018 IPR003714 PhoH-like protein GO:0005524 CU254_RS26450 74be86e3e3f8748c26a03ac94350695c 348 Gene3D G3DSA:3.40.50.300 120 327 2.7E-31 T 28-03-2018 CU254_RS26450 74be86e3e3f8748c26a03ac94350695c 348 SUPERFAMILY SSF52540 123 290 5.58E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CU254_RS23745 ad6150549fc2ab8b153e6ab0fa1ee6d1 233 SUPERFAMILY SSF51261 67 222 1.73E-47 T 28-03-2018 IPR011055 Duplicated hybrid motif CU254_RS23745 ad6150549fc2ab8b153e6ab0fa1ee6d1 233 Pfam PF01551 Peptidase family M23 123 217 1.1E-29 T 28-03-2018 IPR016047 Peptidase M23 CU254_RS23745 ad6150549fc2ab8b153e6ab0fa1ee6d1 233 Gene3D G3DSA:2.70.70.10 43 224 2.5E-44 T 28-03-2018 CU254_RS07115 94837ecc8a75773c9eff4a8aac6be404 179 Pfam PF12028 Protein of unknown function (DUF3515) 21 176 1.0E-49 T 28-03-2018 IPR021903 Protein of unknown function DUF3515 CU254_RS10230 48c5076c39e3643a894c4a12bea49201 533 Pfam PF00474 Sodium:solute symporter family 46 455 2.6E-88 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CU254_RS40595 e0630894f813fa030ccfe80cd731dd19 270 SUPERFAMILY SSF53335 11 237 9.14E-57 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS40595 e0630894f813fa030ccfe80cd731dd19 270 Pfam PF04072 Leucine carboxyl methyltransferase 17 171 3.0E-17 T 28-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CU254_RS40595 e0630894f813fa030ccfe80cd731dd19 270 PIRSF PIRSF028177 1 270 1.4E-76 T 28-03-2018 IPR016874 Tetracenomycin polyketide synthesis O-methyltransferase TcmP GO:0017000|GO:1901106 CU254_RS40595 e0630894f813fa030ccfe80cd731dd19 270 Gene3D G3DSA:3.40.50.150 2 247 7.8E-36 T 28-03-2018 CU254_RS36185 d71f67d4097305e3adcffd3d4bf62142 106 Gene3D G3DSA:1.25.40.20 1 106 2.2E-11 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain CU254_RS36185 d71f67d4097305e3adcffd3d4bf62142 106 SUPERFAMILY SSF48403 3 95 3.98E-6 T 28-03-2018 IPR020683 Ankyrin repeat-containing domain CU254_RS22700 d9220eda03faf071b5f6c955a75dd15c 160 Pfam PF05423 Mycobacterium membrane protein 73 152 6.4E-10 T 28-03-2018 IPR008693 Transport accessory protein MmpS CU254_RS03385 32ad2bad7dbc2c7e9335c79f48ad7586 174 Pfam PF04138 GtrA-like protein 27 157 1.4E-24 T 28-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 CU254_RS40010 14756dd2f833fa37f5ad740c80fe1b03 277 Pfam PF02517 CAAX protease self-immunity 173 260 2.4E-12 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CU254_RS33650 d6dd9e3f6756af91ae0d16de421f6948 262 Pfam PF13490 Putative zinc-finger 8 37 5.6E-5 T 28-03-2018 IPR027383 Putative zinc-finger CU254_RS23945 32234030eeadf18d9790ed8e1eaa7b6a 143 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 3 117 2.1E-13 T 28-03-2018 CU254_RS23945 32234030eeadf18d9790ed8e1eaa7b6a 143 SUPERFAMILY SSF54593 2 140 1.75E-27 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS23945 32234030eeadf18d9790ed8e1eaa7b6a 143 Gene3D G3DSA:3.10.180.10 1 141 2.9E-28 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS16410 1772f7727c7f0e2f603e5d1ba05bcc66 565 Pfam PF00474 Sodium:solute symporter family 116 509 3.0E-35 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CU254_RS16410 1772f7727c7f0e2f603e5d1ba05bcc66 565 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 491 511 - T 28-03-2018 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 CU254_RS38245 910705b77a6394cdf61f9baff9ff842a 1063 Gene3D G3DSA:2.60.120.610 46 212 9.6E-43 T 28-03-2018 IPR027451 Arabinofuranosyltransferase, domain 1 CU254_RS38245 910705b77a6394cdf61f9baff9ff842a 1063 Pfam PF14896 EmbC C-terminal domain 798 1053 7.4E-59 T 28-03-2018 IPR032731 Arabinosyltransferase, C-terminal CU254_RS38245 910705b77a6394cdf61f9baff9ff842a 1063 Pfam PF14896 EmbC C-terminal domain 708 762 1.1E-9 T 28-03-2018 IPR032731 Arabinosyltransferase, C-terminal CU254_RS38245 910705b77a6394cdf61f9baff9ff842a 1063 Pfam PF04602 Mycobacterial cell wall arabinan synthesis protein 24 662 2.4E-231 T 28-03-2018 IPR007680 Arabinofuranosyltransferase, N-terminal GO:0052636|GO:0071766 CU254_RS02520 f04f0a7572ec97c3d65295480fdd005a 302 Pfam PF00892 EamA-like transporter family 150 285 2.3E-19 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CU254_RS02520 f04f0a7572ec97c3d65295480fdd005a 302 Pfam PF00892 EamA-like transporter family 8 139 6.6E-18 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CU254_RS02520 f04f0a7572ec97c3d65295480fdd005a 302 SUPERFAMILY SSF103481 188 289 2.48E-14 T 28-03-2018 CU254_RS02520 f04f0a7572ec97c3d65295480fdd005a 302 SUPERFAMILY SSF103481 40 142 1.31E-9 T 28-03-2018 CU254_RS42150 00439ca2eb8ee944d999bec2979398bd 138 Gene3D G3DSA:1.10.260.40 14 107 1.6E-7 T 28-03-2018 CU254_RS26075 7a5338e83714f4560d4594f2e6554112 286 Gene3D G3DSA:3.20.20.70 4 282 2.1E-89 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CU254_RS26075 7a5338e83714f4560d4594f2e6554112 286 Pfam PF05853 beta-keto acid cleavage enzyme 6 278 1.1E-86 T 28-03-2018 IPR008567 3-keto-5-aminohexanoate cleavage enzyme GO:0016740|GO:0019475 KEGG: 00310+2.3.1.247|KEGG: 00600+2.3.1.24 CU254_RS34570 7259ff17587cb1a1e9eacb067b593ac3 223 SUPERFAMILY SSF55729 36 203 1.3E-15 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS34570 7259ff17587cb1a1e9eacb067b593ac3 223 Pfam PF13302 Acetyltransferase (GNAT) domain 36 180 1.1E-9 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS34570 7259ff17587cb1a1e9eacb067b593ac3 223 Gene3D G3DSA:3.40.630.30 28 220 2.0E-15 T 28-03-2018 CU254_RS32935 ccfd0b682d296eedc90ba02360201fbb 152 Pfam PF14155 Domain of unknown function (DUF4307) 32 141 2.2E-30 T 28-03-2018 IPR025443 Protein of unknown function DUF4307 CU254_RS30590 585128fa0bd56ee72c7f9e15b20696de 480 Pfam PF00860 Permease family 39 433 3.8E-26 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CU254_RS36975 57be1955b1bd5b4107bd4755c824f29b 186 Pfam PF09335 SNARE associated Golgi protein 20 145 2.8E-14 T 28-03-2018 IPR032816 SNARE associated Golgi protein CU254_RS42160 ed066d516d336fc09bcedcc064c0a3f3 180 SUPERFAMILY SSF55729 88 150 8.15E-14 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS42160 ed066d516d336fc09bcedcc064c0a3f3 180 Pfam PF13508 Acetyltransferase (GNAT) domain 89 144 5.4E-7 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS42160 ed066d516d336fc09bcedcc064c0a3f3 180 Gene3D G3DSA:3.40.630.30 25 172 1.1E-15 T 28-03-2018 CU254_RS05530 e4010cfc93b926992e6e2fe5eb53d90c 385 Gene3D G3DSA:1.10.287.850 74 163 2.2E-7 T 28-03-2018 CU254_RS15455 eaaf0ce7c52a5c0db5b1e4569e2d32c1 111 Gene3D G3DSA:1.10.720.10 80 110 4.9E-6 T 28-03-2018 CU254_RS01070 ea0bdf0055652db58b8d5a84b793a159 276 Pfam PF13622 Thioesterase-like superfamily 30 270 7.8E-41 T 28-03-2018 CU254_RS01070 ea0bdf0055652db58b8d5a84b793a159 276 SUPERFAMILY SSF54637 18 121 1.29E-10 T 28-03-2018 IPR029069 HotDog domain CU254_RS01070 ea0bdf0055652db58b8d5a84b793a159 276 SUPERFAMILY SSF54637 155 270 7.46E-9 T 28-03-2018 IPR029069 HotDog domain CU254_RS01070 ea0bdf0055652db58b8d5a84b793a159 276 Gene3D G3DSA:3.10.129.10 156 276 0.0038 T 28-03-2018 CU254_RS01070 ea0bdf0055652db58b8d5a84b793a159 276 Gene3D G3DSA:3.10.129.10 1 119 2.3E-20 T 28-03-2018 CU254_RS33050 2e3e669b62aff09ea97512eb6d43143f 495 Gene3D G3DSA:2.60.40.810 313 448 1.1E-12 T 28-03-2018 CU254_RS33050 2e3e669b62aff09ea97512eb6d43143f 495 Gene3D G3DSA:2.60.40.10 170 304 6.0E-8 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS23680 8ffe6c828401320c77ec6f454262b76d 104 SUPERFAMILY SSF69118 9 103 4.32E-29 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CU254_RS23680 8ffe6c828401320c77ec6f454262b76d 104 Pfam PF02627 Carboxymuconolactone decarboxylase family 16 99 2.6E-23 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CU254_RS23680 8ffe6c828401320c77ec6f454262b76d 104 Gene3D G3DSA:1.20.1290.10 2 104 4.0E-29 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CU254_RS13185 301cb9679e77c7e541d87bc913702092 263 Pfam PF08892 YqcI/YcgG family 34 247 1.7E-57 T 28-03-2018 IPR014988 Uncharacterised protein family, YqcI/YcgG CU254_RS09425 de6086e086aa3f2fe81e5aa826b95e8d 69 Gene3D G3DSA:2.40.50.140 1 67 2.0E-12 T 28-03-2018 CU254_RS33955 174462dd1ff174cdb86068eac9803f12 302 SUPERFAMILY SSF51735 1 277 3.63E-30 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS33955 174462dd1ff174cdb86068eac9803f12 302 Pfam PF13460 NAD(P)H-binding 7 156 6.2E-13 T 28-03-2018 IPR016040 NAD(P)-binding domain CU254_RS33955 174462dd1ff174cdb86068eac9803f12 302 Gene3D G3DSA:3.40.50.720 1 288 4.9E-21 T 28-03-2018 CU254_RS26495 6f5eb2c06e4cc1b4139fa499d98f075d 170 SUPERFAMILY SSF103473 15 79 1.16E-5 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS34540 577dbbdd7f0425ab159d028b4ec5c629 259 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 8 225 9.2E-43 T 28-03-2018 IPR018713 Domain of unknown function DUF2236 CU254_RS27065 2748dac4f6a1bbec645e5f57d3e1cc21 609 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 80 234 4.3E-29 T 28-03-2018 CU254_RS19330 74d60c7f6c42b9cc4c88e0b7918ab1fe 262 Gene3D G3DSA:3.40.50.1980 137 260 4.3E-6 T 28-03-2018 CU254_RS19330 74d60c7f6c42b9cc4c88e0b7918ab1fe 262 SUPERFAMILY SSF53807 15 261 3.05E-10 T 28-03-2018 CU254_RS19330 74d60c7f6c42b9cc4c88e0b7918ab1fe 262 Gene3D G3DSA:3.40.50.1980 35 136 0.0014 T 28-03-2018 CU254_RS18950 a22ebfc6f9d1eee672366008d9f75f3e 255 Pfam PF00535 Glycosyl transferase family 2 16 180 1.9E-30 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CU254_RS18950 a22ebfc6f9d1eee672366008d9f75f3e 255 SUPERFAMILY SSF53448 13 226 4.41E-40 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS18950 a22ebfc6f9d1eee672366008d9f75f3e 255 Gene3D G3DSA:3.90.550.10 2 251 5.5E-34 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CU254_RS32600 d1a52d276ec2004f96c92ec577504388 107 Pfam PF02467 Transcription factor WhiB 39 102 2.6E-26 T 28-03-2018 IPR034768 WhiB-like iron-sulfur binding domain CU254_RS32600 d1a52d276ec2004f96c92ec577504388 107 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 30 107 18.719 T 28-03-2018 IPR003482 Transcription factor WhiB CU254_RS40705 a333abc55674d2b7d9d6e8793d3e2f3f 284 Pfam PF01061 ABC-2 type transporter 62 227 2.2E-19 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CU254_RS32180 2852d5b6d6d0021facfab752b4cc3e7f 522 Pfam PF13556 PucR C-terminal helix-turn-helix domain 460 516 6.4E-17 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CU254_RS32180 2852d5b6d6d0021facfab752b4cc3e7f 522 Gene3D G3DSA:3.30.450.40 112 269 3.3E-9 T 28-03-2018 IPR029016 GAF domain-like CU254_RS32180 2852d5b6d6d0021facfab752b4cc3e7f 522 Gene3D G3DSA:1.10.10.60 461 495 6.9E-5 T 28-03-2018 CU254_RS14720 80d4f4c14fa0268390c4392048c27110 167 Gene3D G3DSA:1.20.1170.10 5 145 9.0E-4 T 28-03-2018 CU254_RS23365 51fe4ac25f102f76fc2ecc8010185fe3 247 Pfam PF06724 Domain of Unknown Function (DUF1206) 80 150 1.0E-13 T 28-03-2018 IPR009597 Domain of unknown function DUF1206 CU254_RS23365 51fe4ac25f102f76fc2ecc8010185fe3 247 Pfam PF06724 Domain of Unknown Function (DUF1206) 2 65 1.9E-16 T 28-03-2018 IPR009597 Domain of unknown function DUF1206 CU254_RS23365 51fe4ac25f102f76fc2ecc8010185fe3 247 Pfam PF06724 Domain of Unknown Function (DUF1206) 176 244 2.0E-14 T 28-03-2018 IPR009597 Domain of unknown function DUF1206 CU254_RS04550 0a1d1291fc881253715ef180798f4608 480 Pfam PF13699 Domain of unknown function (DUF4157) 22 99 1.4E-29 T 28-03-2018 IPR025295 Domain of unknown function DUF4157 CU254_RS07520 b2901515f568a961eccbca787f1f6f07 138 Pfam PF04138 GtrA-like protein 8 124 2.0E-9 T 28-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 CU254_RS40480 fd8e23f26b010deeb227e9385412b02e 70 Pfam PF13619 KTSC domain 7 64 7.2E-24 T 28-03-2018 IPR025309 KTSC domain CU254_RS09355 3c08076b562c20a28886770193abf3e2 447 Pfam PF00324 Amino acid permease 17 388 3.4E-34 T 28-03-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0006810|GO:0016020|GO:0055085 CU254_RS09355 3c08076b562c20a28886770193abf3e2 447 PIRSF PIRSF006060 1 446 9.1E-56 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CU254_RS03870 f7c8b2bebc009a326da2cbde619e8d76 115 Pfam PF06689 ClpX C4-type zinc finger 4 39 7.1E-16 T 28-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 CU254_RS03870 f7c8b2bebc009a326da2cbde619e8d76 115 SMART SM00994 2 41 3.2E-16 T 28-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 CU254_RS03870 f7c8b2bebc009a326da2cbde619e8d76 115 SUPERFAMILY SSF57716 4 38 4.99E-9 T 28-03-2018 CU254_RS03785 fbf533918392ed54089ae4597c87a594 168 SUPERFAMILY SSF49503 85 150 1.22E-5 T 28-03-2018 IPR008972 Cupredoxin CU254_RS41660 ad8e14c20cf699e1b7ba2d45dfc7f82c 253 Pfam PF16259 Domain of unknown function (DUF4913) 139 231 1.2E-24 T 28-03-2018 IPR032584 Protein of unknown function DUF4913 CU254_RS36515 4ecd5dc236a3b7441030c2f5583781a1 120 TIGRFAM TIGR03816 tadE_like_DECH: helicase/secretion neighborhood TadE-like protein 8 115 2.9E-26 T 28-03-2018 IPR021202 Apoptosis inhibitor Rv3654c-like CU254_RS06845 4feea43c96422b9aa4ddd4bdc7739630 196 ProDom PD072817 ANTIGEN WEIGHT MOLECULAR LOW CFP-6 CGL1269 SEQUENCING DIRECT 24 132 2.0E-18 T 28-03-2018 IPR020535 Low molecular weight antigen Cfp6 CU254_RS06845 4feea43c96422b9aa4ddd4bdc7739630 196 Pfam PF10756 Bacterial PH domain 62 131 4.7E-13 T 28-03-2018 IPR019692 Protein of unknown function DUF2581 CU254_RS08845 6bfc2e7c041807b7afab8de26bc4a817 329 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 51 75 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CU254_RS08845 6bfc2e7c041807b7afab8de26bc4a817 329 SUPERFAMILY SSF53613 4 302 6.7E-54 T 28-03-2018 IPR029056 Ribokinase-like CU254_RS08845 6bfc2e7c041807b7afab8de26bc4a817 329 Pfam PF00294 pfkB family carbohydrate kinase 34 299 4.1E-40 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CU254_RS08845 6bfc2e7c041807b7afab8de26bc4a817 329 Gene3D G3DSA:3.40.1190.20 5 326 6.4E-40 T 28-03-2018 IPR029056 Ribokinase-like CU254_RS02215 416a2c8eeacee2b6aa1466ede74b312b 94 Gene3D G3DSA:1.10.287.1060 1 91 4.7E-4 T 28-03-2018 CU254_RS17965 e7e526494e351dd2ae44511f2e8f0095 379 Pfam PF09375 Imelysin 142 365 1.5E-13 T 28-03-2018 IPR018976 Peptidase M75, Imelysin CU254_RS19525 18da3d404c1138e7fe177969778ebd06 218 SUPERFAMILY SSF53335 42 215 1.47E-28 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS19525 18da3d404c1138e7fe177969778ebd06 218 Gene3D G3DSA:3.40.50.150 44 215 8.0E-20 T 28-03-2018 CU254_RS19525 18da3d404c1138e7fe177969778ebd06 218 Pfam PF13649 Methyltransferase domain 69 161 6.9E-7 T 28-03-2018 CU254_RS08950 8c4f0cdf65cba9dd2901ac82e5143f27 204 Gene3D G3DSA:3.40.50.300 17 201 0.0017 T 28-03-2018 CU254_RS20750 631a72dded2f25c68096539d3684d884 157 Gene3D G3DSA:3.10.450.50 1 141 3.1E-31 T 28-03-2018 CU254_RS20750 631a72dded2f25c68096539d3684d884 157 SUPERFAMILY SSF54427 2 138 7.64E-36 T 28-03-2018 IPR032710 NTF2-like domain CU254_RS20750 631a72dded2f25c68096539d3684d884 157 Pfam PF13577 SnoaL-like domain 3 127 4.2E-30 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CU254_RS33990 0821eef98531b061807b009ee574f766 243 Pfam PF10979 Protein of unknown function (DUF2786) 7 45 3.9E-14 T 28-03-2018 IPR024498 Domain of unknown function DUF2786 CU254_RS33990 0821eef98531b061807b009ee574f766 243 ProDom PD120223 SCO3432 GENE ML2604 GP79 GP77 CGL2230 MB0190 5 228 1.0E-26 T 28-03-2018 CU254_RS25440 b6da8f0088bade51dff242c0d2e758dd 267 Gene3D G3DSA:3.30.70.260 80 183 1.7E-10 T 28-03-2018 CU254_RS25440 b6da8f0088bade51dff242c0d2e758dd 267 SUPERFAMILY SSF55021 84 131 2.12E-6 T 28-03-2018 CU254_RS08415 5a91b73c4e018dc0e96a08582f845ff4 388 Gene3D G3DSA:3.40.640.10 51 282 1.2E-40 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CU254_RS08415 5a91b73c4e018dc0e96a08582f845ff4 388 SUPERFAMILY SSF53383 14 382 2.42E-81 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CU254_RS08415 5a91b73c4e018dc0e96a08582f845ff4 388 Gene3D G3DSA:3.90.1150.10 283 387 1.8E-18 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CU254_RS08415 5a91b73c4e018dc0e96a08582f845ff4 388 Pfam PF00155 Aminotransferase class I and II 41 381 1.0E-50 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CU254_RS33940 28f5d2c5f035f192e803655f3eba5f84 123 PIRSF PIRSF009151 1 123 6.5E-63 T 28-03-2018 IPR008497 Protein of unknown function DUF779 CU254_RS33940 28f5d2c5f035f192e803655f3eba5f84 123 Pfam PF05610 Protein of unknown function (DUF779) 14 112 1.5E-47 T 28-03-2018 IPR008497 Protein of unknown function DUF779 CU254_RS02980 a6306fe8918c4332959fe5a58075d927 477 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 256 263 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CU254_RS02980 a6306fe8918c4332959fe5a58075d927 477 Pfam PF00171 Aldehyde dehydrogenase family 30 477 1.3E-165 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CU254_RS02980 a6306fe8918c4332959fe5a58075d927 477 SUPERFAMILY SSF53720 15 477 7.07E-162 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CU254_RS02980 a6306fe8918c4332959fe5a58075d927 477 Gene3D G3DSA:3.40.309.10 273 466 1.8E-70 T 28-03-2018 CU254_RS02980 a6306fe8918c4332959fe5a58075d927 477 Gene3D G3DSA:3.40.605.10 10 272 3.9E-98 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CU254_RS24845 3178f9bbe3e5311fd49668632b98e27b 404 Pfam PF06224 Winged helix DNA-binding domain 37 381 1.5E-70 T 28-03-2018 IPR009351 Protein of unknown function DUF1006 CU254_RS38710 cce6abd521f82d1cb1699b2bf39b2bcc 191 Pfam PF14436 Bacterial EndoU nuclease 10 76 1.4E-9 T 28-03-2018 IPR029501 Bacterial EndoU nuclease CU254_RS05285 ba97a1822cfcaa7a53c9d6c4e3340b15 97 Gene3D G3DSA:1.10.287.1060 1 94 3.7E-10 T 28-03-2018 CU254_RS00335 eeef905957ac01bf0a30947803849149 304 Gene3D G3DSA:3.40.1090.10 1 269 6.7E-21 T 28-03-2018 CU254_RS00335 eeef905957ac01bf0a30947803849149 304 SUPERFAMILY SSF52151 1 72 2.88E-24 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CU254_RS00335 eeef905957ac01bf0a30947803849149 304 SUPERFAMILY SSF52151 110 239 2.88E-24 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CU254_RS00335 eeef905957ac01bf0a30947803849149 304 Pfam PF01734 Patatin-like phospholipase 1 200 5.2E-8 T 28-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 CU254_RS26125 9dbf9176b64ce03637d8945196f5bd2a 518 Pfam PF03806 AbgT putative transporter family 30 518 3.0E-144 T 28-03-2018 IPR004697 p-Aminobenzoyl-glutamate transport protein AbgT GO:0015558|GO:1902604 CU254_RS24665 eb5d20f44db783de063da6e6fd9c04a0 423 Pfam PF01882 Protein of unknown function DUF58 201 280 9.1E-19 T 28-03-2018 IPR002881 Domain of unknown function DUF58 CU254_RS24665 eb5d20f44db783de063da6e6fd9c04a0 423 Gene3D G3DSA:3.40.50.410 207 380 4.3E-4 T 28-03-2018 IPR002035 von Willebrand factor, type A CU254_RS23305 267aabce0b99fd29a4ec40e7a1f5a7a9 389 Gene3D G3DSA:1.10.10.60 314 362 8.5E-7 T 28-03-2018 CU254_RS23305 267aabce0b99fd29a4ec40e7a1f5a7a9 389 Pfam PF13556 PucR C-terminal helix-turn-helix domain 326 384 4.6E-23 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CU254_RS35095 2fa35491c25fb3864468826508ff6756 487 Pfam PF00860 Permease family 29 441 1.8E-28 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CU254_RS42320 346206702b0638e90e8ba36a7bb7e4ba 217 Gene3D G3DSA:2.60.40.810 94 202 1.2E-16 T 28-03-2018 CU254_RS42320 346206702b0638e90e8ba36a7bb7e4ba 217 Gene3D G3DSA:2.60.40.10 1 93 2.8E-8 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS42320 346206702b0638e90e8ba36a7bb7e4ba 217 SUPERFAMILY SSF49478 101 163 9.42E-5 T 28-03-2018 CU254_RS04895 1e35e05c3365de74c98a23925f7081b1 136 Pfam PF16708 Lipoprotein confined to pathogenic Mycobacterium 37 121 7.8E-20 T 28-03-2018 IPR032018 Putative lipoprotein, pathogenic bacteria CU254_RS15875 c5cd9484940634f8f0df83ebda6f38ec 358 Pfam PF06081 Aromatic acid exporter family member 1 28 165 1.1E-8 T 28-03-2018 IPR010343 Aromatic acid exporter family member 1 CU254_RS25655 5726fa78d47012010f26ef1595ae61d8 95 Gene3D G3DSA:1.10.150.130 11 94 2.3E-6 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CU254_RS21305 2613846ad860bc5c8ad60f95b9a15360 243 SUPERFAMILY SSF49879 26 81 1.1E-7 T 28-03-2018 IPR008984 SMAD/FHA domain GO:0005515 CU254_RS21305 2613846ad860bc5c8ad60f95b9a15360 243 Gene3D G3DSA:2.60.200.20 21 87 3.8E-6 T 28-03-2018 CU254_RS12600 537df2eb62d704b7241cf0fdb9687977 402 Gene3D G3DSA:2.170.15.10 115 345 1.1E-20 T 28-03-2018 CU254_RS37700 b43d94cda00df0e1672a4a24a3eb4080 394 Pfam PF09594 Glycosyltransferase family 87 69 301 4.5E-53 T 28-03-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 CU254_RS38540 a61fb31b9f8fbd65dff38fbfcf481277 315 Pfam PF04168 A predicted alpha-helical domain with a conserved ER motif. 1 300 1.0E-77 T 28-03-2018 IPR007296 Domain of unknown function DUF403 CU254_RS17545 9b09caa3d3622b2730fc1083f7524d2e 239 Pfam PF01925 Sulfite exporter TauE/SafE 5 233 5.8E-33 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CU254_RS15515 1563517282141b98eb869cc31ee57913 233 Gene3D G3DSA:2.30.320.10 5 220 1.8E-13 T 28-03-2018 CU254_RS15240 b4ffb7d0efde96a1694940bea7eff97d 173 Gene3D G3DSA:1.10.10.10 1 92 8.5E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS15240 b4ffb7d0efde96a1694940bea7eff97d 173 SUPERFAMILY SSF46785 3 167 1.04E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS15240 b4ffb7d0efde96a1694940bea7eff97d 173 Pfam PF03551 Transcriptional regulator PadR-like family 7 77 5.9E-15 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CU254_RS10780 e9cb5d3204bd85ef47e4786a310f3bf2 121 Pfam PF01638 HxlR-like helix-turn-helix 26 111 6.7E-21 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type CU254_RS10780 e9cb5d3204bd85ef47e4786a310f3bf2 121 Gene3D G3DSA:1.10.10.10 24 121 2.8E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS10780 e9cb5d3204bd85ef47e4786a310f3bf2 121 SUPERFAMILY SSF46785 10 120 2.83E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS16815 30d1430b24209831c67c12c120565f29 159 Pfam PF07681 DoxX 4 88 4.2E-11 T 28-03-2018 IPR032808 DoxX family CU254_RS36080 fb739557b374e563c399e1b440e03cba 409 Pfam PF04286 Protein of unknown function (DUF445) 23 150 4.7E-10 T 28-03-2018 IPR007383 Protein of unknown function DUF445 CU254_RS33080 52c78ac4db5e789d531ee1af7213b020 92 SUPERFAMILY SSF140453 12 84 1.06E-9 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CU254_RS33080 52c78ac4db5e789d531ee1af7213b020 92 Gene3D G3DSA:1.10.287.1060 13 79 5.5E-9 T 28-03-2018 CU254_RS24530 a4bae17f3115c2f7c65e91f8ff3975dc 241 Pfam PF07103 Protein of unknown function (DUF1365) 5 230 1.1E-53 T 28-03-2018 IPR010775 Protein of unknown function DUF1365 CU254_RS13300 f68dc14b15243d448ae5c8e1582d8a85 137 Pfam PF04686 Streptomyces sporulation and cell division protein, SsgA 26 120 3.0E-32 T 28-03-2018 IPR006776 Sporulation-specific cell division protein SsgB GO:0051301 CU254_RS40150 252116fbb50bc225931fc291d1251fd3 327 Pfam PF13845 Septum formation 69 285 8.3E-72 T 28-03-2018 IPR026004 Septum formation-related domain CU254_RS02775 05ea0039e2092f425492693edb7dfe05 337 PIRSF PIRSF035875 6 309 2.8E-33 T 28-03-2018 IPR017039 Virulence factor BrkB CU254_RS02775 05ea0039e2092f425492693edb7dfe05 337 TIGRFAM TIGR00766 TIGR00766: inner membrane protein YhjD 23 289 1.5E-64 T 28-03-2018 IPR005274 Inner membrane protein YhjD CU254_RS02775 05ea0039e2092f425492693edb7dfe05 337 Pfam PF03631 Virulence factor BrkB 34 290 2.1E-44 T 28-03-2018 IPR017039 Virulence factor BrkB CU254_RS11135 4f3a9d426c5c3217d7556d20ba014752 224 Pfam PF09335 SNARE associated Golgi protein 59 174 3.6E-23 T 28-03-2018 IPR032816 SNARE associated Golgi protein CU254_RS36985 e9d8f869015ef4f5f4d35c28af4dbee9 299 Pfam PF00892 EamA-like transporter family 7 130 3.4E-11 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CU254_RS36985 e9d8f869015ef4f5f4d35c28af4dbee9 299 Pfam PF00892 EamA-like transporter family 142 282 3.2E-14 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CU254_RS36985 e9d8f869015ef4f5f4d35c28af4dbee9 299 SUPERFAMILY SSF103481 184 287 1.83E-10 T 28-03-2018 CU254_RS36985 e9d8f869015ef4f5f4d35c28af4dbee9 299 SUPERFAMILY SSF103481 40 134 8.37E-13 T 28-03-2018 CU254_RS34035 c465dcf918f4f22094ec56482ec20bc3 308 SUPERFAMILY SSF88713 21 292 3.71E-56 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CU254_RS34035 c465dcf918f4f22094ec56482ec20bc3 308 Pfam PF01522 Polysaccharide deacetylase 39 174 4.4E-17 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CU254_RS34035 c465dcf918f4f22094ec56482ec20bc3 308 Gene3D G3DSA:3.20.20.370 33 297 8.5E-53 T 28-03-2018 CU254_RS10730 44b55659a38fad26bb713791d3dd6c2e 412 Pfam PF03631 Virulence factor BrkB 46 305 1.7E-38 T 28-03-2018 IPR017039 Virulence factor BrkB CU254_RS24020 c6877df17d8dc4b4d1d1baaceaad4418 257 SUPERFAMILY SSF53335 18 255 4.49E-27 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS24020 c6877df17d8dc4b4d1d1baaceaad4418 257 Pfam PF13649 Methyltransferase domain 57 149 1.0E-10 T 28-03-2018 CU254_RS24020 c6877df17d8dc4b4d1d1baaceaad4418 257 Gene3D G3DSA:3.40.50.150 13 257 1.1E-29 T 28-03-2018 CU254_RS04260 eb1c7dc635fbdfe94fc0a4e35ca36418 245 Pfam PF02591 C4-type zinc ribbon domain 203 237 1.5E-11 T 28-03-2018 IPR003743 C4-type zinc ribbon domain CU254_RS04260 eb1c7dc635fbdfe94fc0a4e35ca36418 245 Gene3D G3DSA:1.20.120.330 13 175 9.5E-5 T 28-03-2018 CU254_RS03470 925d9e2353e807357e5fb4d84d7b7c76 142 Pfam PF07681 DoxX 9 91 1.5E-17 T 28-03-2018 IPR032808 DoxX family CU254_RS12495 832880454ab91eec0e671f322ea3a60b 338 Pfam PF02687 FtsX-like permease family 244 329 1.4E-5 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CU254_RS35455 aa17b7e27ec719dad73ad8ef4eb2933b 102 Gene3D G3DSA:1.10.10.10 21 100 1.6E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS35455 aa17b7e27ec719dad73ad8ef4eb2933b 102 Pfam PF11662 Protein of unknown function (DUF3263) 21 92 1.9E-36 T 28-03-2018 IPR021678 Protein of unknown function DUF3263 CU254_RS19645 9383df46a7e000ab42ddeaf1df345f51 337 Gene3D G3DSA:2.130.10.10 34 186 5.3E-4 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CU254_RS19645 9383df46a7e000ab42ddeaf1df345f51 337 Gene3D G3DSA:2.130.10.10 187 335 4.7E-11 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CU254_RS19645 9383df46a7e000ab42ddeaf1df345f51 337 SUPERFAMILY SSF101898 125 329 1.12E-15 T 28-03-2018 CU254_RS19610 2b1a06d4143e2aa151dec813b8fdd30b 332 Gene3D G3DSA:3.20.20.80 23 329 2.8E-14 T 28-03-2018 CU254_RS19610 2b1a06d4143e2aa151dec813b8fdd30b 332 SUPERFAMILY SSF51445 100 326 5.36E-14 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CU254_RS05175 af9129213e84ef74fdf424a08eb63fab 195 Pfam PF09335 SNARE associated Golgi protein 47 152 1.5E-14 T 28-03-2018 IPR032816 SNARE associated Golgi protein CU254_RS38495 2dd9344bbe5ab7eae14ef58c9f0b49e2 767 Gene3D G3DSA:2.160.20.80 40 541 2.1E-7 T 28-03-2018 CU254_RS03955 4330651e97538327149def7fc11b1e9d 106 Pfam PF16170 Domain of unknown function (DUF4873) 4 94 9.3E-35 T 28-03-2018 IPR032371 Domain of unknown function DUF4873 CU254_RS03280 b83b01959bf805de2de07d00b5c5527d 517 SUPERFAMILY SSF50969 62 129 1.73E-14 T 28-03-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like CU254_RS03280 b83b01959bf805de2de07d00b5c5527d 517 SUPERFAMILY SSF50969 354 505 1.73E-14 T 28-03-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like CU254_RS03280 b83b01959bf805de2de07d00b5c5527d 517 SUPERFAMILY SSF50969 201 263 1.73E-14 T 28-03-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like CU254_RS03280 b83b01959bf805de2de07d00b5c5527d 517 Gene3D G3DSA:2.120.10.30 257 512 2.2E-7 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CU254_RS03280 b83b01959bf805de2de07d00b5c5527d 517 Gene3D G3DSA:2.130.10.10 9 256 8.1E-9 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CU254_RS03405 5cd4a6888a48078020f60f9baacf2e9e 445 Pfam PF09594 Glycosyltransferase family 87 100 342 9.5E-49 T 28-03-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 CU254_RS24645 8a4c3bad51720e29f3b0796f8352da65 193 SUPERFAMILY SSF140459 25 121 1.49E-6 T 28-03-2018 CU254_RS24645 8a4c3bad51720e29f3b0796f8352da65 193 Gene3D G3DSA:1.10.287.850 31 119 1.2E-5 T 28-03-2018 CU254_RS35050 84882edb5e9b01a53f3fda14391e338b 196 Pfam PF10801 Protein of unknown function (DUF2537) 113 192 1.4E-23 T 28-03-2018 IPR024244 Protein of unknown function DUF2537 CU254_RS31305 5492cd48f1ee8de46e3c855e70b67be7 216 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 11 208 1.2E-60 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 CU254_RS31305 5492cd48f1ee8de46e3c855e70b67be7 216 SUPERFAMILY SSF55821 5 208 3.97E-55 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CU254_RS31305 5492cd48f1ee8de46e3c855e70b67be7 216 Pfam PF01300 Telomere recombination 24 197 1.0E-43 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 CU254_RS31305 5492cd48f1ee8de46e3c855e70b67be7 216 Gene3D G3DSA:3.90.870.10 1 213 7.9E-66 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CU254_RS32775 001ee3ff0fbef0bd02feb2e6c900a33a 321 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 8 291 36.863 T 28-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 CU254_RS32775 001ee3ff0fbef0bd02feb2e6c900a33a 321 Pfam PF02401 LytB protein 10 287 2.3E-89 T 28-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 CU254_RS32775 001ee3ff0fbef0bd02feb2e6c900a33a 321 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 10 287 2.6E-97 T 28-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 CU254_RS18760 cccf07618e76e94619f92eea6517b691 532 Pfam PF04185 Phosphoesterase family 44 491 2.2E-83 T 28-03-2018 IPR007312 Phosphoesterase GO:0016788 CU254_RS18760 cccf07618e76e94619f92eea6517b691 532 Gene3D G3DSA:3.40.720.10 40 491 2.9E-17 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CU254_RS15415 1b2e48d1f83c094f4802c0b09e70a21f 138 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 13 128 4.2E-29 T 28-03-2018 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III CU254_RS36995 b19bde5f25f957d9df2d730838d84774 217 Pfam PF09335 SNARE associated Golgi protein 32 160 1.5E-19 T 28-03-2018 IPR032816 SNARE associated Golgi protein CU254_RS14100 93f858e3a6d7f5855071f27da14f8d89 142 Pfam PF07681 DoxX 14 87 4.1E-7 T 28-03-2018 IPR032808 DoxX family CU254_RS22090 14c02dd6671316cca571ea43b204fa54 159 Gene3D G3DSA:3.30.420.40 15 103 5.9E-4 T 28-03-2018 CU254_RS13640 7a2bab251b9f5bdc5f5c3391f57751f8 135 Gene3D G3DSA:1.10.10.10 29 130 5.2E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS13640 7a2bab251b9f5bdc5f5c3391f57751f8 135 Pfam PF01638 HxlR-like helix-turn-helix 32 113 7.8E-26 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type CU254_RS13640 7a2bab251b9f5bdc5f5c3391f57751f8 135 SUPERFAMILY SSF46785 18 128 4.76E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS27675 24d97b04012e3ec5d3096ecf6e805155 207 Pfam PF14124 Domain of unknown function (DUF4291) 14 191 8.3E-73 T 28-03-2018 IPR025633 Protein of unknown function DUF4291 CU254_RS09925 2374c65cbae82079a48c9b885a5a4178 263 Pfam PF02405 Permease MlaE 43 252 1.4E-65 T 28-03-2018 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 CU254_RS04985 71d12416ce69ab0b03ba876abde16f0a 183 SUPERFAMILY SSF46689 2 63 1.03E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CU254_RS04985 71d12416ce69ab0b03ba876abde16f0a 183 SUPERFAMILY SSF48498 66 161 1.22E-6 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CU254_RS04985 71d12416ce69ab0b03ba876abde16f0a 183 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 51 1.5E-4 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CU254_RS04985 71d12416ce69ab0b03ba876abde16f0a 183 Gene3D G3DSA:1.10.357.10 1 182 7.9E-21 T 28-03-2018 CU254_RS21905 021bd29e294fadf421f125e8f379b8e4 94 Gene3D G3DSA:2.60.40.10 2 90 4.5E-13 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS21905 021bd29e294fadf421f125e8f379b8e4 94 SUPERFAMILY SSF81296 13 83 5.25E-12 T 28-03-2018 IPR014756 Immunoglobulin E-set CU254_RS39180 dd830ca0be13e719859e96d52d0c7f37 214 Gene3D G3DSA:3.40.630.30 20 197 9.3E-19 T 28-03-2018 CU254_RS39180 dd830ca0be13e719859e96d52d0c7f37 214 Pfam PF00583 Acetyltransferase (GNAT) family 52 136 3.1E-6 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS39180 dd830ca0be13e719859e96d52d0c7f37 214 SUPERFAMILY SSF55729 31 141 3.66E-12 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS24520 a1213ea49f06905098b48def11537c57 253 Pfam PF13490 Putative zinc-finger 8 37 1.7E-7 T 28-03-2018 IPR027383 Putative zinc-finger CU254_RS24520 a1213ea49f06905098b48def11537c57 253 Pfam PF10099 Anti-sigma-K factor rskA 58 248 1.8E-32 T 28-03-2018 IPR018764 Anti-sigma K factor RskA GO:0005886|GO:0016021 CU254_RS01510 8f99a3d2700583202955eb0332621629 339 Gene3D G3DSA:2.160.20.10 73 338 2.4E-14 T 28-03-2018 IPR012334 Pectin lyase fold CU254_RS01510 8f99a3d2700583202955eb0332621629 339 SUPERFAMILY SSF51126 108 334 1.15E-13 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor CU254_RS32530 c01ed32362de23f75625f1a142c9030f 759 Gene3D G3DSA:3.40.50.1820 491 735 3.0E-14 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS32530 c01ed32362de23f75625f1a142c9030f 759 SUPERFAMILY SSF53474 540 625 7.67E-5 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS21405 a4d53c2025e264965f48a88578a29745 86 Gene3D G3DSA:1.20.120.330 16 85 2.1E-4 T 28-03-2018 CU254_RS08585 2078f083dac75c6e5853132d52e72ce6 276 Pfam PF05552 Conserved TM helix 86 129 3.7E-9 T 28-03-2018 IPR008910 Conserved TM helix CU254_RS08585 2078f083dac75c6e5853132d52e72ce6 276 Pfam PF05552 Conserved TM helix 1 39 7.8E-11 T 28-03-2018 IPR008910 Conserved TM helix CU254_RS17585 b1fc0284484240c4606d1dcd283053b5 479 Pfam PF00474 Sodium:solute symporter family 32 403 4.1E-11 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CU254_RS25195 6b4a261dd9cba786896a9c9d8e7fba37 823 Gene3D G3DSA:3.90.176.10 549 764 7.6E-8 T 28-03-2018 CU254_RS09945 6707153f5a3b11fbca1d9dd9737dcfe2 346 Gene3D G3DSA:1.20.1170.10 113 292 8.4E-6 T 28-03-2018 CU254_RS09945 6707153f5a3b11fbca1d9dd9737dcfe2 346 Pfam PF02470 MlaD protein 42 115 1.3E-15 T 28-03-2018 IPR003399 Mce/MlaD CU254_RS09945 6707153f5a3b11fbca1d9dd9737dcfe2 346 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 180 198 1.5E-10 T 28-03-2018 IPR005693 Virulence factor Mce protein CU254_RS09945 6707153f5a3b11fbca1d9dd9737dcfe2 346 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 93 109 1.5E-10 T 28-03-2018 IPR005693 Virulence factor Mce protein CU254_RS09945 6707153f5a3b11fbca1d9dd9737dcfe2 346 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 31 51 1.5E-10 T 28-03-2018 IPR005693 Virulence factor Mce protein CU254_RS09945 6707153f5a3b11fbca1d9dd9737dcfe2 346 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 300 319 1.5E-10 T 28-03-2018 IPR005693 Virulence factor Mce protein CU254_RS09945 6707153f5a3b11fbca1d9dd9737dcfe2 346 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 131 155 1.5E-10 T 28-03-2018 IPR005693 Virulence factor Mce protein CU254_RS09945 6707153f5a3b11fbca1d9dd9737dcfe2 346 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 16 294 3.5E-57 T 28-03-2018 IPR005693 Virulence factor Mce protein CU254_RS32100 eb906f2f400a9feffc254882ed501a2a 246 Gene3D G3DSA:1.20.1170.10 13 218 3.5E-4 T 28-03-2018 CU254_RS09145 57c06e93509ddf9ff9b4d77d9a6a5528 363 Pfam PF11203 Putative type VII ESX secretion system translocon, EccE 192 285 2.8E-17 T 28-03-2018 IPR021368 Type VII secretion system protein EccE CU254_RS21085 6af49dfb83dacf5abf66c733bbc01b81 31 TIGRFAM TIGR02107 PQQ_syn_pqqA: coenzyme PQQ precursor peptide PqqA 8 27 2.9E-7 T 28-03-2018 IPR011725 Coenzyme PQQ biosynthesis protein A GO:0018189 CU254_RS21085 6af49dfb83dacf5abf66c733bbc01b81 31 Pfam PF08042 PqqA family 7 25 1.1E-8 T 28-03-2018 IPR011725 Coenzyme PQQ biosynthesis protein A GO:0018189 CU254_RS26955 139a50d371bd6b03a8a0e942d44acebc 474 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 358 441 7.9E-14 T 28-03-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain CU254_RS26955 139a50d371bd6b03a8a0e942d44acebc 474 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 92 260 5.1E-34 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CU254_RS26955 139a50d371bd6b03a8a0e942d44acebc 474 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 92 259 3.5E-40 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CU254_RS00130 596326ac5e0727544a496fa6913cfa53 358 Pfam PF11991 Tryptophan dimethylallyltransferase 9 216 1.4E-8 T 28-03-2018 IPR017795 Aromatic prenyltransferase, DMATS-type GO:0009820|GO:0016765 CU254_RS21665 aa779a4e2f8339cd20ad482d14ad7535 83 Gene3D G3DSA:1.20.120.520 1 40 1.5E-4 T 28-03-2018 CU254_RS21665 aa779a4e2f8339cd20ad482d14ad7535 83 Gene3D G3DSA:1.20.120.520 41 80 0.026 T 28-03-2018 CU254_RS21495 3059b5c4c44558f37da77a7375b3d4fc 173 Pfam PF14081 Domain of unknown function (DUF4262) 24 146 1.1E-34 T 28-03-2018 IPR025358 Protein of unknown function DUF4262 CU254_RS24810 6c5f17aa14304bd5d4d0e0be8792bfe6 411 Hamap MF_00221 Divalent metal cation transporter MntH [mntH]. 7 409 34.155 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CU254_RS24810 6c5f17aa14304bd5d4d0e0be8792bfe6 411 PRINTS PR00447 Natural resistance-associated macrophage protein signature 198 221 4.3E-29 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CU254_RS24810 6c5f17aa14304bd5d4d0e0be8792bfe6 411 PRINTS PR00447 Natural resistance-associated macrophage protein signature 327 344 4.3E-29 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CU254_RS24810 6c5f17aa14304bd5d4d0e0be8792bfe6 411 PRINTS PR00447 Natural resistance-associated macrophage protein signature 95 121 4.3E-29 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CU254_RS24810 6c5f17aa14304bd5d4d0e0be8792bfe6 411 PRINTS PR00447 Natural resistance-associated macrophage protein signature 123 142 4.3E-29 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CU254_RS24810 6c5f17aa14304bd5d4d0e0be8792bfe6 411 PRINTS PR00447 Natural resistance-associated macrophage protein signature 149 170 4.3E-29 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CU254_RS24810 6c5f17aa14304bd5d4d0e0be8792bfe6 411 PRINTS PR00447 Natural resistance-associated macrophage protein signature 299 318 4.3E-29 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CU254_RS24810 6c5f17aa14304bd5d4d0e0be8792bfe6 411 Pfam PF01566 Natural resistance-associated macrophage protein 36 383 1.7E-113 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CU254_RS24810 6c5f17aa14304bd5d4d0e0be8792bfe6 411 TIGRFAM TIGR01197 nramp: metal ion transporter, metal ion (Mn2+/Fe2+) transporter (Nramp) family 17 377 1.3E-85 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CU254_RS15915 4d178fac96c547e86e1c9d6a3bb658b5 124 Pfam PF10025 Uncharacterized conserved protein (DUF2267) 2 118 1.1E-23 T 28-03-2018 IPR018727 Protein of unknown function DUF2267 CU254_RS14450 170254c519fa44f09317491d60a758ec 192 Pfam PF03551 Transcriptional regulator PadR-like family 14 89 1.4E-11 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CU254_RS14450 170254c519fa44f09317491d60a758ec 192 Gene3D G3DSA:1.10.10.10 3 102 4.6E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS14450 170254c519fa44f09317491d60a758ec 192 SUPERFAMILY SSF46785 12 183 2.16E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS07320 a401c9b0da595358db5d6d4c513304cf 241 Gene3D G3DSA:1.20.5.620 95 147 1.3E-8 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain CU254_RS07320 a401c9b0da595358db5d6d4c513304cf 241 Gene3D G3DSA:1.20.5.620 148 196 2.6E-6 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain CU254_RS07320 a401c9b0da595358db5d6d4c513304cf 241 Gene3D G3DSA:1.20.5.620 60 94 7.4E-5 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain CU254_RS40285 b03abbe7de87ceb7317897a57fe40e82 305 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 8 282 3.1E-23 T 28-03-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD CU254_RS18310 5861784f046a6e2683ac4121d3132f2e 235 Pfam PF14230 Domain of unknown function (DUF4333) 148 225 1.2E-25 T 28-03-2018 IPR025637 Domain of unknown function DUF4333 CU254_RS13130 f85d2a88e9ecb424305d9cea2b8a47c7 131 Pfam PF17240 Family of unknown function (DUF5313) 3 124 4.8E-46 T 28-03-2018 IPR035197 Protein of unknown function DUF5313 CU254_RS21935 249e3a278ca8eb11405512936b6c6905 370 Pfam PF01757 Acyltransferase family 9 333 1.3E-17 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CU254_RS05030 2756082c0e0d8747b3690a7348b01831 126 Gene3D G3DSA:3.30.1310.10 3 100 8.4E-13 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CU254_RS13435 eefcd767635556d89affc662253539af 244 Pfam PF01925 Sulfite exporter TauE/SafE 8 239 5.8E-29 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CU254_RS08385 a9dc4f279fe378b75a6f099d0ee29a57 414 Gene3D G3DSA:1.20.1250.20 222 412 1.4E-21 T 28-03-2018 CU254_RS08385 a9dc4f279fe378b75a6f099d0ee29a57 414 Pfam PF07690 Major Facilitator Superfamily 40 374 1.7E-16 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CU254_RS08385 a9dc4f279fe378b75a6f099d0ee29a57 414 Gene3D G3DSA:1.20.1250.20 26 221 5.8E-14 T 28-03-2018 CU254_RS08385 a9dc4f279fe378b75a6f099d0ee29a57 414 SUPERFAMILY SSF103473 35 411 9.94E-37 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS19450 79f6399b404a8a633e832e293c586c26 191 TIGRFAM TIGR03847 TIGR03847: conserved hypothetical protein 5 180 2.0E-78 T 28-03-2018 IPR021441 Protein of unknown function DUF3090 CU254_RS19450 79f6399b404a8a633e832e293c586c26 191 Pfam PF11290 Protein of unknown function (DUF3090) 6 176 9.2E-69 T 28-03-2018 IPR021441 Protein of unknown function DUF3090 CU254_RS32580 d6160e2c2a159eef862b20774b2da560 117 Pfam PF12005 Protein of unknown function (DUF3499) 4 114 6.8E-46 T 28-03-2018 IPR021888 Protein of unknown function DUF3499 CU254_RS39645 0d839f9cc5528d27efebaebefad7cedf 223 Pfam PF14103 Domain of unknown function (DUF4276) 11 218 6.8E-36 T 28-03-2018 IPR025455 Protein of unknown function DUF4276 CU254_RS01740 308a567cb374a7e696c48b5841dea281 269 Pfam PF00561 alpha/beta hydrolase fold 27 125 1.3E-19 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CU254_RS01740 308a567cb374a7e696c48b5841dea281 269 Gene3D G3DSA:3.40.50.1820 1 262 3.3E-35 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS01740 308a567cb374a7e696c48b5841dea281 269 SUPERFAMILY SSF53474 4 254 2.2E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CU254_RS24195 8ac2d2558755755adfe42224fcb51fbb 65 Gene3D G3DSA:1.10.357.10 1 65 5.2E-5 T 28-03-2018 CU254_RS13280 9211305bb179560595c36c19a5b893e2 329 Pfam PF02653 Branched-chain amino acid transport system / permease component 44 318 1.8E-50 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CU254_RS13280 9211305bb179560595c36c19a5b893e2 329 Gene3D G3DSA:1.10.3470.10 4 325 4.3E-32 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CU254_RS26680 14d7fd437c20d6369f116ede1bac5744 188 Pfam PF05685 Putative restriction endonuclease 21 176 3.5E-30 T 28-03-2018 IPR008538 Domain of unknown function DUF820 CU254_RS26680 14d7fd437c20d6369f116ede1bac5744 188 Gene3D G3DSA:3.90.1570.10 10 181 5.2E-36 T 28-03-2018 CU254_RS26680 14d7fd437c20d6369f116ede1bac5744 188 SUPERFAMILY SSF52980 13 159 2.47E-30 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CU254_RS33320 38a50ab59ef9891a6dd480c8699303b6 856 Pfam PF02687 FtsX-like permease family 301 394 1.3E-7 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CU254_RS33320 38a50ab59ef9891a6dd480c8699303b6 856 Pfam PF02687 FtsX-like permease family 759 839 6.4E-6 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CU254_RS05655 06653ffe86b4d9aa96de1c8273518335 272 Pfam PF01061 ABC-2 type transporter 21 235 2.7E-26 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CU254_RS05655 06653ffe86b4d9aa96de1c8273518335 272 PIRSF PIRSF006648 2 271 1.1E-72 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CU254_RS18345 719be4cf4a8a02ac45e12d4c147833b9 75 Gene3D G3DSA:1.10.1220.10 2 44 3.0E-6 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CU254_RS27585 14113196ef3a32b85a117d4ca3dec02f 852 Gene3D G3DSA:1.25.40.10 235 602 1.3E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS40050 a05029a3970b35c1054315013a9d20d0 504 PIRSF PIRSF006446 1 492 5.3E-133 T 28-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 CU254_RS40050 a05029a3970b35c1054315013a9d20d0 504 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 6 470 8.5E-162 T 28-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 CU254_RS27875 cad32f49a29a2bfacea3b722ffc80aa4 273 Pfam PF05103 DivIVA protein 15 127 2.7E-9 T 28-03-2018 IPR007793 DivIVA family CU254_RS42185 4ae0e5ae5b1ed4c44e015043b803bb83 459 Pfam PF02624 YcaO cyclodehydratase, ATP-ad Mg2+-binding 122 428 2.9E-54 T 28-03-2018 IPR003776 YcaO-like domain CU254_RS42185 4ae0e5ae5b1ed4c44e015043b803bb83 459 TIGRFAM TIGR00702 TIGR00702: YcaO-type kinase domain 74 429 4.0E-65 T 28-03-2018 IPR003776 YcaO-like domain CU254_RS25825 5609f778cd6d63b44669177fd81f8e44 242 Pfam PF06386 Gas vesicle synthesis protein GvpL/GvpF 3 239 1.5E-54 T 28-03-2018 IPR009430 Gas vesicle protein GvpL/GvpF GO:0031411|GO:0031412 CU254_RS14055 197ca0bf4ae15ac027a2639e24a9608b 214 Gene3D G3DSA:3.30.1380.10 85 212 6.9E-5 T 28-03-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CU254_RS12320 86b8838cf79d3fcf79876a742d4a7478 219 Pfam PF11010 Protein of unknown function (DUF2848) 25 212 5.4E-58 T 28-03-2018 IPR021269 Protein of unknown function DUF2848 CU254_RS38735 de6562ea518d95e0cb23193d197930f8 231 SUPERFAMILY SSF69318 19 195 2.09E-9 T 28-03-2018 CU254_RS38735 de6562ea518d95e0cb23193d197930f8 231 Gene3D G3DSA:4.10.1080.10 5 206 2.4E-8 T 28-03-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 CU254_RS24650 ae3c943bd02006d7634c2dc54b8cbb44 178 Pfam PF12079 Protein of unknown function (DUF3558) 22 175 4.9E-19 T 28-03-2018 IPR024520 Protein of unknown function DUF3558 CU254_RS11435 7b1128af0b4409fa50d6efcf48bbc6a0 499 Gene3D G3DSA:2.115.10.20 59 146 1.5E-5 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CU254_RS11435 7b1128af0b4409fa50d6efcf48bbc6a0 499 Gene3D G3DSA:2.115.10.20 147 348 5.3E-21 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CU254_RS11435 7b1128af0b4409fa50d6efcf48bbc6a0 499 SUPERFAMILY SSF75005 132 244 1.83E-17 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CU254_RS33210 8f4d5b03f13a38fea9925431e71af6dc 284 Gene3D G3DSA:1.10.287.70 23 185 9.0E-8 T 28-03-2018 CU254_RS33210 8f4d5b03f13a38fea9925431e71af6dc 284 SUPERFAMILY SSF81324 25 123 2.28E-8 T 28-03-2018 CU254_RS01865 f259b51239e00b678082b68f061f8467 111 Gene3D G3DSA:1.10.287.1060 3 101 8.9E-5 T 28-03-2018 CU254_RS01865 f259b51239e00b678082b68f061f8467 111 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 9 96 1.1E-5 T 28-03-2018 IPR022536 ESX-1 secretion-associated protein EspC GO:0009306 CU254_RS36300 28ef70fb348aef608be8546dd1cc2f2c 150 Pfam PF11377 Protein of unknown function (DUF3180) 9 142 1.7E-35 T 28-03-2018 IPR021517 Protein of unknown function DUF3180 CU254_RS00770 e82af151094391917c24a3234557c486 86 Pfam PF04149 Domain of unknown function (DUF397) 22 76 4.2E-17 T 28-03-2018 IPR007278 Domain of unknown function DUF397 CU254_RS19575 1723cf75b9659bae6517059586c17969 212 Pfam PF14273 Domain of unknown function (DUF4360) 29 208 2.4E-65 T 28-03-2018 IPR025649 Protein of unknown function DUF4360 CU254_RS06865 ac7b0731bd21508c923bac3d3b664aff 88 Pfam PF04149 Domain of unknown function (DUF397) 21 78 9.9E-11 T 28-03-2018 IPR007278 Domain of unknown function DUF397 CU254_RS10320 7e57eecf1189630ae5ce18b661110240 383 Pfam PF04434 SWIM zinc finger 125 144 4.9E-6 T 28-03-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 CU254_RS21180 b99c9f9becdd90bd463ea33f58c7fbf8 150 Pfam PF13581 Histidine kinase-like ATPase domain 30 102 1.0E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CU254_RS21385 9d8a939455d0cece57c93d771e57a27e 122 Pfam PF03779 SPW repeat 18 61 2.7E-11 T 28-03-2018 IPR005530 SPW repeat CU254_RS21385 9d8a939455d0cece57c93d771e57a27e 122 Pfam PF03779 SPW repeat 70 119 2.4E-8 T 28-03-2018 IPR005530 SPW repeat CU254_RS26365 8e7d1d31d4f03e71923ecd9ef5106e21 212 Pfam PF04203 Sortase family 110 208 1.7E-9 T 28-03-2018 IPR005754 Sortase family CU254_RS26365 8e7d1d31d4f03e71923ecd9ef5106e21 212 SUPERFAMILY SSF63817 94 209 2.63E-10 T 28-03-2018 IPR023365 Sortase domain CU254_RS26365 8e7d1d31d4f03e71923ecd9ef5106e21 212 Gene3D G3DSA:2.40.260.10 68 212 9.0E-17 T 28-03-2018 IPR023365 Sortase domain CU254_RS22110 5f01a5a123bbfa378d9e035bc6fd713d 168 Pfam PF04138 GtrA-like protein 35 154 3.2E-13 T 28-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 CU254_RS28185 e3c6c51224773823911f60288f998119 397 Gene3D G3DSA:1.20.91.10 230 315 2.1E-4 T 28-03-2018 CU254_RS28185 e3c6c51224773823911f60288f998119 397 Pfam PF00999 Sodium/hydrogen exchanger family 14 371 2.3E-55 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CU254_RS09465 3ee44dc6560ec9f068f29702b2fccf0e 214 Pfam PF03243 Alkylmercury lyase 73 145 1.2E-6 T 28-03-2018 IPR004927 Alkylmercury lyase GO:0018836|GO:0046413 CU254_RS09465 3ee44dc6560ec9f068f29702b2fccf0e 214 SUPERFAMILY SSF160387 84 191 4.97E-9 T 28-03-2018 CU254_RS16975 c1a3426a778916b2b06d04e9d37d13a0 142 Gene3D G3DSA:2.30.110.10 2 138 3.0E-5 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS03730 e59e1bb571ebe28b7029de9a56ad3828 55 Pfam PF11314 Protein of unknown function (DUF3117) 4 53 7.2E-29 T 28-03-2018 IPR021465 Protein of unknown function DUF3117 CU254_RS03815 1b38a0ee421b3a8cf27febe2907cbe5f 197 Pfam PF13828 Domain of unknown function (DUF4190) 122 180 1.2E-13 T 28-03-2018 IPR025241 Domain of unknown function DUF4190 CU254_RS17955 4f59f19b4b6b4e4c3576cd609c08ac57 134 Pfam PF15585 Immunity protein 7 1 133 2.4E-30 T 28-03-2018 IPR028965 Immunity protein 7 CU254_RS38490 810efb047f9b113a08f95fcfce4ad69b 190 Gene3D G3DSA:3.40.1580.10 11 184 2.8E-5 T 28-03-2018 CU254_RS34645 814a24401fedb5041a99fe89c1d822f4 116 Gene3D G3DSA:1.10.260.40 23 99 3.6E-6 T 28-03-2018 CU254_RS30915 59a205253c65306dc948b2e0c1b9601e 179 Gene3D G3DSA:2.60.40.1240 84 172 1.4E-5 T 28-03-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain CU254_RS37050 d0c4f6b21976359a205d1d663d2b51bd 145 Pfam PF10066 Uncharacterized conserved protein (DUF2304) 5 106 4.1E-25 T 28-03-2018 IPR019277 Protein of unknown function DUF2304 CU254_RS39885 b7aa8c50e1bc0b55189c41086789ad85 169 ProDom PD095338 YXII PLASMID 3 156 3.0E-17 T 28-03-2018 IPR020323 Protein of unknown function DUF2716 CU254_RS39885 b7aa8c50e1bc0b55189c41086789ad85 169 Pfam PF10898 Protein of unknown function (DUF2716) 3 143 7.4E-47 T 28-03-2018 IPR020323 Protein of unknown function DUF2716 CU254_RS26640 f4aeeaf091bc168d488a450e31a06537 116 SUPERFAMILY SSF52038 23 104 7.59E-18 T 28-03-2018 IPR000468 Barstar (barnase inhibitor) CU254_RS26640 f4aeeaf091bc168d488a450e31a06537 116 Pfam PF01337 Barstar (barnase inhibitor) 23 102 6.4E-22 T 28-03-2018 IPR000468 Barstar (barnase inhibitor) CU254_RS26640 f4aeeaf091bc168d488a450e31a06537 116 Gene3D G3DSA:3.30.370.10 20 110 9.7E-22 T 28-03-2018 IPR000468 Barstar (barnase inhibitor) CU254_RS29270 f30214d94303518dd4477c01ff41f4be 215 Gene3D G3DSA:3.50.30.40 5 185 3.6E-49 T 28-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CU254_RS29270 f30214d94303518dd4477c01ff41f4be 215 SUPERFAMILY SSF89562 10 176 1.31E-40 T 28-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CU254_RS29270 f30214d94303518dd4477c01ff41f4be 215 Pfam PF03737 Aldolase/RraA 12 163 4.9E-35 T 28-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CU254_RS10720 5570b8cf794483c7055fe7d03e2c4b81 92 Pfam PF11238 Protein of unknown function (DUF3039) 30 86 6.4E-29 T 28-03-2018 IPR021400 Protein of unknown function DUF3039 CU254_RS26700 20514a6740ba32d0c6482c7ff417371a 287 Pfam PF00892 EamA-like transporter family 6 137 2.5E-8 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CU254_RS26700 20514a6740ba32d0c6482c7ff417371a 287 Pfam PF00892 EamA-like transporter family 151 284 5.7E-11 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CU254_RS26700 20514a6740ba32d0c6482c7ff417371a 287 SUPERFAMILY SSF103481 193 285 3.92E-12 T 28-03-2018 CU254_RS26700 20514a6740ba32d0c6482c7ff417371a 287 SUPERFAMILY SSF103481 44 141 1.1E-13 T 28-03-2018 CU254_RS11370 13677de710fa8f57c5923a0988ff09df 412 Pfam PF02378 Phosphotransferase system, EIIC 26 329 8.1E-68 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CU254_RS42655 1830150af8cd444857a0f7ff68b96cff 588 Pfam PF03432 Relaxase/Mobilisation nuclease domain 110 244 1.3E-6 T 28-03-2018 IPR005094 Endonuclease relaxase, MobA/VirD2 CU254_RS09210 012f216b19bc7219a3fbbc99d4a34632 271 Gene3D G3DSA:3.40.50.150 4 204 5.5E-37 T 28-03-2018 CU254_RS09210 012f216b19bc7219a3fbbc99d4a34632 271 SUPERFAMILY SSF53335 25 216 2.61E-37 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CU254_RS09210 012f216b19bc7219a3fbbc99d4a34632 271 Pfam PF13847 Methyltransferase domain 40 163 7.8E-28 T 28-03-2018 IPR025714 Methyltransferase domain CU254_RS10170 b4e0afa671bbc0760ef939d16b627aa9 67 Pfam PF04149 Domain of unknown function (DUF397) 8 60 2.6E-22 T 28-03-2018 IPR007278 Domain of unknown function DUF397 CU254_RS03270 8e3841c6a0af798f4f4ccb4b3bb04af2 70 Pfam PF13822 Acyl-CoA carboxylase epsilon subunit 5 63 7.3E-17 T 28-03-2018 IPR032716 Acyl-CoA carboxylase epsilon subunit CU254_RS38515 66823f9a1164bb86e2a9dcdab8778c74 247 Pfam PF14011 EspG family 9 239 5.2E-43 T 28-03-2018 IPR025734 EspG family CU254_RS04125 218d5996dd7d483dcb9369454cc4ee26 210 Pfam PF13559 Domain of unknown function (DUF4129) 128 196 1.8E-16 T 28-03-2018 IPR025403 Domain of unknown function DUF4129 CU254_RS30425 d3c0390f85157574ec5726eaa7830ed0 376 Gene3D G3DSA:1.20.1250.20 21 328 1.3E-6 T 28-03-2018 CU254_RS10365 4c5fe481037897fcc4cbaac9a069f8cf 546 TIGRFAM TIGR04141 TIGR04141: sporadically distributed protein, TIGR04141 family 9 534 3.4E-119 T 28-03-2018 IPR026487 Sporadically distributed protein CHP04141 CU254_RS09035 a954dcb9cb1ef3f106b43d695df44d71 99 SUPERFAMILY SSF140453 4 98 2.75E-9 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CU254_RS09035 a954dcb9cb1ef3f106b43d695df44d71 99 Gene3D G3DSA:1.10.287.1060 1 99 1.6E-10 T 28-03-2018 CU254_RS14290 10b3ff4a7a03148cb53ff33155656869 141 Pfam PF03779 SPW repeat 83 127 4.0E-5 T 28-03-2018 IPR005530 SPW repeat CU254_RS29145 e32993053d787bbc342e03a2f11eb23c 76 Pfam PF04149 Domain of unknown function (DUF397) 16 70 1.9E-16 T 28-03-2018 IPR007278 Domain of unknown function DUF397 CU254_RS29865 7ac8f0f8515ceba5e20892e8f84f2be9 66 Gene3D G3DSA:3.30.70.20 1 64 4.1E-4 T 28-03-2018 CU254_RS29865 7ac8f0f8515ceba5e20892e8f84f2be9 66 SUPERFAMILY SSF54862 3 62 2.93E-7 T 28-03-2018 CU254_RS29865 7ac8f0f8515ceba5e20892e8f84f2be9 66 Pfam PF13459 4Fe-4S single cluster domain 5 61 1.6E-11 T 28-03-2018 CU254_RS17075 2e4a5e5891aed60b38b8fc0d6ffc4096 527 Gene3D G3DSA:1.10.10.10 398 521 0.0023 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS17075 2e4a5e5891aed60b38b8fc0d6ffc4096 527 Pfam PF13556 PucR C-terminal helix-turn-helix domain 460 518 2.1E-20 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CU254_RS40440 2983b2dbd5c97e61502903de451e89be 418 Pfam PF04230 Polysaccharide pyruvyl transferase 30 211 6.7E-11 T 28-03-2018 IPR007345 Polysaccharide pyruvyl transferase CU254_RS26330 b843f9b70a22dd70f32e510c716f7703 215 Gene3D G3DSA:3.40.50.620 37 177 1.8E-26 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CU254_RS26330 b843f9b70a22dd70f32e510c716f7703 215 Pfam PF02698 DUF218 domain 48 193 1.3E-22 T 28-03-2018 IPR003848 Domain of unknown function DUF218 CU254_RS26200 182f72fdb9895a44714ed1bae293ab92 240 Pfam PF14011 EspG family 16 236 5.3E-26 T 28-03-2018 IPR025734 EspG family CU254_RS20530 33fe6a004137c97f48aa423376967e29 89 Pfam PF02583 Metal-sensitive transcriptional repressor 9 84 4.4E-24 T 28-03-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 CU254_RS25840 ac311b937cffec6cd604f01876bae97a 304 Gene3D G3DSA:1.10.260.40 25 100 1.6E-5 T 28-03-2018 CU254_RS17280 6648d28c9723c49786fa8c7bde3dfa6b 136 Gene3D G3DSA:3.10.129.10 1 136 7.5E-23 T 28-03-2018 CU254_RS17280 6648d28c9723c49786fa8c7bde3dfa6b 136 SUPERFAMILY SSF54637 2 135 1.37E-25 T 28-03-2018 IPR029069 HotDog domain CU254_RS17280 6648d28c9723c49786fa8c7bde3dfa6b 136 Pfam PF13279 Thioesterase-like superfamily 11 131 1.7E-10 T 28-03-2018 CU254_RS14360 710b9cafb4a8e876118483f78e1ad4ec 97 TIGRFAM TIGR03967 mycofact_MftB: putative mycofactocin binding protein MftB 15 92 3.7E-27 T 28-03-2018 IPR023850 Putative mycofactocin binding protein MftB CU254_RS03210 c9f317c144c7dcca67f958c257fe57f7 182 Pfam PF08044 Domain of unknown function (DUF1707) 9 61 2.7E-21 T 28-03-2018 IPR012551 Protein of unknown function DUF1707 CU254_RS15750 7628040523528e98030511e0771cad95 348 SUPERFAMILY SSF144052 18 339 3.4E-12 T 28-03-2018 CU254_RS30135 ce15e2c2d9422c9ceced91f15bba89bf 152 SUPERFAMILY SSF55729 25 151 1.03E-16 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CU254_RS30135 ce15e2c2d9422c9ceced91f15bba89bf 152 Gene3D G3DSA:3.40.630.30 23 152 5.9E-17 T 28-03-2018 CU254_RS30135 ce15e2c2d9422c9ceced91f15bba89bf 152 Pfam PF00583 Acetyltransferase (GNAT) family 45 146 4.7E-6 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CU254_RS04885 ab12a734bcb3d5131a2cad137c332c4c 230 Pfam PF13796 Putative sensor 23 206 3.1E-38 T 28-03-2018 IPR025828 Putative sensor domain CU254_RS38425 9de8c960843edbc30fc7be6b578f4394 125 Pfam PF04075 F420H(2)-dependent quinone reductase 23 98 8.7E-6 T 28-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CU254_RS38425 9de8c960843edbc30fc7be6b578f4394 125 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 23 108 4.2E-17 T 28-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CU254_RS38425 9de8c960843edbc30fc7be6b578f4394 125 Gene3D G3DSA:2.30.110.10 5 112 7.8E-16 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CU254_RS29345 590446ee63404571a746dfde0137abeb 570 Pfam PF02538 Hydantoinase B/oxoprolinase 4 522 1.0E-156 T 28-03-2018 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403 CU254_RS20590 622b6565007775f6c9fe01d6d4131f37 62 Pfam PF04324 BFD-like [2Fe-2S] binding domain 4 49 2.8E-12 T 28-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain CU254_RS00875 da5a50c4f413c794d8ae482975142767 110 Pfam PF13453 Transcription factor zinc-finger 3 39 2.6E-17 T 28-03-2018 IPR027392 Transcription factor zinc-finger CU254_RS08310 f0bd39dd2c36d8acff7881022c521bc2 400 SUPERFAMILY SSF50156 100 214 3.29E-12 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CU254_RS08310 f0bd39dd2c36d8acff7881022c521bc2 400 Gene3D G3DSA:2.30.42.10 156 241 5.5E-13 T 28-03-2018 CU254_RS08310 f0bd39dd2c36d8acff7881022c521bc2 400 Pfam PF02163 Peptidase family M50 11 350 3.2E-49 T 28-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 CU254_RS33805 143c51e20f300b6077d02b4a15402372 122 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 45 81 1.2E-12 T 28-03-2018 IPR019933 DivIVA domain CU254_RS33805 143c51e20f300b6077d02b4a15402372 122 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 39 2.0E-8 T 28-03-2018 IPR019933 DivIVA domain CU254_RS26180 bae16f73b93ef484b845bd730cf1d18e 261 Gene3D G3DSA:1.10.287.1060 65 162 3.1E-4 T 28-03-2018 CU254_RS29905 a7e375c3e1e1b09a52990dde1e4d6c79 533 Pfam PF05960 Bacterial protein of unknown function (DUF885) 20 531 6.3E-118 T 28-03-2018 IPR010281 Protein of unknown function DUF885 CU254_RS28685 6dfc6d788a932ea47c2cf873c5726b0e 361 Gene3D G3DSA:2.60.40.10 269 361 2.5E-5 T 28-03-2018 IPR013783 Immunoglobulin-like fold CU254_RS22650 00fe5bfa15e7fe514a6ac7e9b2ca3e96 213 Gene3D G3DSA:3.40.50.1240 36 203 3.6E-7 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CU254_RS21780 7d1a1a7c4df064baae2bcdc979a21065 141 Pfam PF04686 Streptomyces sporulation and cell division protein, SsgA 26 122 1.9E-33 T 28-03-2018 IPR006776 Sporulation-specific cell division protein SsgB GO:0051301 CU254_RS14690 7a8ba24dc2ab1580da4cd95675cb6bd6 160 Pfam PF17388 Tail assembly protein Gp24 and Gp25 4 103 4.7E-7 T 28-03-2018 IPR020132 Tail assembly protein Gp24/Gp25 CU254_RS05020 38ade5a638bbfc94b08929d2de3d4529 104 Gene3D G3DSA:1.10.287.1060 1 102 2.2E-8 T 28-03-2018 CU254_RS32555 f9d11e1a6c54738c81f1e0d435c7f0d4 220 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 22 165 2.3E-10 T 28-03-2018 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system CU254_RS11670 fff3769f6d9b2834a8f0762ff385115f 425 Pfam PF06224 Winged helix DNA-binding domain 27 404 1.9E-58 T 28-03-2018 IPR009351 Protein of unknown function DUF1006 CU254_RS11935 55c75e8199c78105be5ecf81da0d66bc 397 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 163 309 6.8E-46 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CU254_RS11935 55c75e8199c78105be5ecf81da0d66bc 397 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 163 309 3.3E-43 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CU254_RS18275 29dea602c6c8c23da77da75127d9612c 330 Pfam PF13280 WYL domain 149 320 3.5E-26 T 28-03-2018 IPR026881 WYL domain CU254_RS21260 14f3e6be379da7db55dbce5f092b94f8 136 Gene3D G3DSA:1.10.287.1060 17 131 2.0E-5 T 28-03-2018 CU254_RS24865 ba6a90c2bd3cfe842ba0b23a7d3877b2 140 Pfam PF13181 Tetratricopeptide repeat 106 136 1.3E-5 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CU254_RS24865 ba6a90c2bd3cfe842ba0b23a7d3877b2 140 Gene3D G3DSA:1.25.20.10 9 138 8.7E-6 T 28-03-2018 CU254_RS04960 9260b956c82caada59f2e2654d43ff08 242 Gene3D G3DSA:1.10.10.10 3 241 4.3E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS40450 643f5e60a69d233487f0f87297a094aa 192 Pfam PF10759 Protein of unknown function (DUF2587) 37 192 2.9E-78 T 28-03-2018 IPR019695 Bacterial proteasome activator GO:0061136 CU254_RS20875 24ed1437a0686c2a2846c49bf7da1d65 439 Gene3D G3DSA:1.10.4080.10 94 439 7.2E-55 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 CU254_RS20875 24ed1437a0686c2a2846c49bf7da1d65 439 SUPERFAMILY SSF101478 100 431 1.57E-40 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 CU254_RS20875 24ed1437a0686c2a2846c49bf7da1d65 439 Pfam PF03747 ADP-ribosylglycohydrolase 105 404 4.6E-54 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 CU254_RS36255 ce15ebb9ecdd9aa10b1dbf8d287b8256 104 SUPERFAMILY SSF103481 5 102 1.11E-14 T 28-03-2018 CU254_RS36255 ce15ebb9ecdd9aa10b1dbf8d287b8256 104 Pfam PF00893 Small Multidrug Resistance protein 1 93 6.3E-20 T 28-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 CU254_RS15625 5506ebf9dbc6fe32c44dfc9d495537b4 77 Pfam PF09954 Uncharacterized protein conserved in bacteria (DUF2188) 8 55 7.2E-7 T 28-03-2018 IPR018691 Protein of unknown function DUF2188 CU254_RS01430 58258c804248cd480e61f0c711f10d26 460 Gene3D G3DSA:3.40.10.10 370 459 0.0024 T 28-03-2018 IPR035451 Ada-like domain CU254_RS42120 b6e38a6868dc9b41d0c8cc8d2e22b10b 187 Pfam PF14525 AraC-binding-like domain 20 181 1.6E-28 T 28-03-2018 IPR035418 Transcription regulator HTH, AraC- type, ligand binding domain-like CU254_RS42120 b6e38a6868dc9b41d0c8cc8d2e22b10b 187 Gene3D G3DSA:2.60.120.10 24 128 5.3E-4 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CU254_RS14385 9d5911dbc346df3c92a66686b149f23f 243 Pfam PF13490 Putative zinc-finger 3 37 1.0E-9 T 28-03-2018 IPR027383 Putative zinc-finger CU254_RS16765 12414ec22e4e88255f2b8293bc449985 110 Pfam PF03780 Asp23 family, cell envelope-related function 1 97 4.2E-10 T 28-03-2018 IPR005531 Alkaline shock protein Asp23 CU254_RS00115 ee54b0a1ca5b381ff01b576e64991022 176 Pfam PF14325 Domain of unknown function (DUF4383) 18 140 2.5E-24 T 28-03-2018 IPR025492 Protein of unknown function DUF4383 CU254_RS36335 299c204811979435a8dcdc21734361ef 273 Pfam PF14011 EspG family 7 262 1.7E-63 T 28-03-2018 IPR025734 EspG family CU254_RS41245 fa5d73b8e8197a25ca5d2a0907acf9a2 211 Gene3D G3DSA:1.10.3630.10 16 186 4.0E-5 T 28-03-2018 CU254_RS39410 de20cdf1450501113121aa2d4d018a84 126 Pfam PF10756 Bacterial PH domain 46 121 7.0E-11 T 28-03-2018 IPR019692 Protein of unknown function DUF2581 CU254_RS29960 8e64de7384b8066737e58de05f6a5c00 80 Pfam PF13396 Phospholipase_D-nuclease N-terminal 31 71 3.8E-6 T 28-03-2018 IPR027379 Cardiolipin synthase N-terminal CU254_RS41745 b4d3a32fdd4f4101911b44d570f58129 150 Pfam PF05713 Bacterial mobilisation protein (MobC) 95 132 1.5E-5 T 28-03-2018 IPR008687 Bacterial mobilisation CU254_RS13160 0f4c81725d519e764e9fb448ec2bfbed 337 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 14 258 2.4E-68 T 28-03-2018 IPR014145 DNA ligase D, polymerase domain CU254_RS15045 c8e9fd1547a00d91d5a77a9f85a17150 93 Pfam PF11239 Protein of unknown function (DUF3040) 1 78 2.2E-15 T 28-03-2018 IPR021401 Protein of unknown function DUF3040 CU254_RS34780 8c1c3d6fc2f5b9a2cb13373bf776b65e 262 Gene3D G3DSA:3.40.960.10 145 258 1.8E-4 T 28-03-2018 CU254_RS21400 ef1617dc0c60de507e061df7870b97c6 604 Pfam PF07907 YibE/F-like protein 345 583 2.1E-73 T 28-03-2018 IPR012507 YibE/F-like CU254_RS13560 f8438f2c81f8f5730c6a0cddaefe6b4b 125 Gene3D G3DSA:1.10.287.1060 1 122 1.3E-11 T 28-03-2018 CU254_RS39905 54df1b22d19c473f5faa2dd985866321 146 Pfam PF06170 Protein of unknown function (DUF983) 29 88 4.2E-5 T 28-03-2018 IPR009325 Protein of unknown function DUF983 CU254_RS15225 1ba3ba312ecccbef93a47f698eb1f7c1 81 TIGRFAM TIGR04076 TIGR04076: TIGR04076 family protein 4 76 5.3E-10 T 28-03-2018 IPR023811 Conserved hypothetical protein CHP04076 CU254_RS15780 bd29d04910d381f2a2017ac3488f50a1 76 Pfam PF09954 Uncharacterized protein conserved in bacteria (DUF2188) 10 64 2.2E-9 T 28-03-2018 IPR018691 Protein of unknown function DUF2188 CU254_RS25985 cdf84380c5ee00ee95e4c7dcbcf26a00 169 Pfam PF03995 Peptidase inhibitor family I36 65 127 3.3E-5 T 28-03-2018 CU254_RS08540 2817c59174c81bd9b0832473589d4318 167 Pfam PF11343 Protein of unknown function (DUF3145) 10 165 6.2E-72 T 28-03-2018 IPR021491 Protein of unknown function DUF3145 CU254_RS05520 b0ac58880605d9a4cba071e02ea21e8a 265 Pfam PF14011 EspG family 19 255 3.7E-33 T 28-03-2018 IPR025734 EspG family CU254_RS37890 417901b2f01db048789d63892ff8c14c 200 Pfam PF12079 Protein of unknown function (DUF3558) 17 194 2.7E-25 T 28-03-2018 IPR024520 Protein of unknown function DUF3558 CU254_RS34355 55d9e3e6dcaf387c464a90cb3579766c 422 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 28 375 6.5E-104 T 28-03-2018 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 CU254_RS34355 55d9e3e6dcaf387c464a90cb3579766c 422 Pfam PF01098 Cell cycle protein 28 376 1.1E-101 T 28-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 CU254_RS13965 3952ef304daddd43b44a3bcd9c5cad30 244 Pfam PF04248 Domain of unknown function (DUF427) 130 224 7.1E-26 T 28-03-2018 IPR007361 Domain of unknown function DUF427 CU254_RS13965 3952ef304daddd43b44a3bcd9c5cad30 244 Pfam PF04248 Domain of unknown function (DUF427) 23 65 3.9E-6 T 28-03-2018 IPR007361 Domain of unknown function DUF427 CU254_RS08545 15cfa959c675722beba186a2a3b53a9b 183 Gene3D G3DSA:3.10.450.50 29 150 7.1E-5 T 28-03-2018 CU254_RS36620 7d86613be62d18c67b795509fc5558c0 240 Gene3D G3DSA:1.10.3290.10 14 239 3.5E-8 T 28-03-2018 IPR003812 Fido domain CU254_RS37290 36e53118dc0f578d77f6c3fcecb6f941 189 Gene3D G3DSA:1.10.287.850 31 182 1.1E-5 T 28-03-2018 CU254_RS31320 4b546bdf604e3e2e2dcffe8218d4dc07 684 TIGRFAM TIGR03296 M6dom_TIGR03296: M6 family metalloprotease domain 107 420 3.0E-41 T 28-03-2018 IPR008757 Peptidase M6-like, domain GO:0006508|GO:0008233 CU254_RS36225 72a007fb8e538afef482eee52098324e 271 Pfam PF11575 FhuF 2Fe-2S C-terminal domain 247 267 5.7E-7 T 28-03-2018 IPR024726 Ferric iron reductase, C-terminal GO:0051537 CU254_RS29795 e78fe2e702c83d375767cccd184a59a8 81 Gene3D G3DSA:3.40.30.20 4 81 2.4E-10 T 28-03-2018 CU254_RS39100 830eac6c7f40d6e4beec58b2fad0306d 100 Gene3D G3DSA:3.30.1310.10 3 73 1.7E-9 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CU254_RS27235 3443dfd0a41f95e78d9d9f2f3e751b82 173 Pfam PF14024 Protein of unknown function (DUF4240) 25 148 2.1E-24 T 28-03-2018 IPR025334 Domain of unknown function (DUF4240 CU254_RS02960 dd75d9b96eb1ace3afdbb018cdf51489 178 Pfam PF14016 Protein of unknown function (DUF4232) 37 169 4.9E-18 T 28-03-2018 IPR025326 Protein of unknown function DUF4232 CU254_RS38395 82f4879e78f8e4f27f28d643090d870f 406 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 114 344 4.4E-40 T 28-03-2018 IPR018713 Domain of unknown function DUF2236 CU254_RS01255 267c548cd109ca38dab62561985871de 96 Pfam PF14012 Protein of unknown function (DUF4229) 14 74 8.9E-14 T 28-03-2018 IPR025323 Protein of unknown function DUF4229 CU254_RS29425 af3d9f57b2c336388e3dc9f8c1afe6d7 161 Gene3D G3DSA:1.25.40.10 2 149 5.8E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CU254_RS30560 7e4e6fdbe0eceba3fe22191b8f637b18 389 Pfam PF09375 Imelysin 147 377 7.9E-16 T 28-03-2018 IPR018976 Peptidase M75, Imelysin CU254_RS22805 d9371e3cefbcba12e8edf5e21bfb4440 508 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 65 225 1.1E-18 T 28-03-2018 CU254_RS04705 6ab8be6fd72bd417990c82681c849b03 403 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 131 348 3.8E-16 T 28-03-2018 IPR018713 Domain of unknown function DUF2236 CU254_RS26415 b2dd0ada43f683e26234cabaf599c40b 328 Pfam PF06271 RDD family 34 158 3.2E-21 T 28-03-2018 IPR010432 RDD CU254_RS14400 3d4997de6253fa903237ce27aa8c0cd3 639 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 360 603 9.9E-82 T 28-03-2018 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related CU254_RS24405 05c8892e1dcafb885dc032f243964392 1104 Pfam PF05960 Bacterial protein of unknown function (DUF885) 570 1094 1.8E-151 T 28-03-2018 IPR010281 Protein of unknown function DUF885 CU254_RS24405 05c8892e1dcafb885dc032f243964392 1104 Pfam PF05960 Bacterial protein of unknown function (DUF885) 20 543 6.2E-152 T 28-03-2018 IPR010281 Protein of unknown function DUF885 CU254_RS34250 cc366cd061a6c128593116c66eff90a4 206 Pfam PF03458 UPF0126 domain 91 162 2.7E-16 T 28-03-2018 IPR005115 Uncharacterised domain UPF0126 CU254_RS34250 cc366cd061a6c128593116c66eff90a4 206 Pfam PF03458 UPF0126 domain 5 79 1.8E-22 T 28-03-2018 IPR005115 Uncharacterised domain UPF0126 CU254_RS05070 7da9ee4110c57ad337861db2423b156c 143 Pfam PF09656 Putative transmembrane protein (PGPGW) 9 60 2.9E-14 T 28-03-2018 IPR019099 Uncharacterised protein family PGPGW, transmembrane CU254_RS13995 f192d6d6fb1a8715a66dbab529721baf 548 TIGRFAM TIGR04215 choice_anch_A: choice-of-anchor A domain 62 337 1.0E-55 T 28-03-2018 IPR026588 Choice-of-anchor A domain CU254_RS40585 c5b6856e10581ee0b97c487ba5fff0a0 162 Pfam PF16571 FBP C-terminal treble-clef zinc-finger 8 158 1.6E-58 T 28-03-2018 IPR032330 Elongation factor G-binding protein, C-terminal treble-clef zinc-finger CU254_RS06100 5185ebba5e2efdb618c6eb7751aaec8f 152 Pfam PF14342 Domain of unknown function (DUF4396) 9 141 7.4E-41 T 28-03-2018 IPR025509 Domain of unknown function DUF4396 CU254_RS24100 50ebeb8aac670bcb746c69ced0adac07 305 Gene3D G3DSA:3.10.180.10 44 185 0.0015 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS03105 5440f3ce86f44f797c9ec405cfa77076 142 Pfam PF14108 Domain of unknown function (DUF4281) 5 130 1.7E-30 T 28-03-2018 IPR025461 ABA DEFICIENT 4-like CU254_RS03205 724130c4a09bf118c8e77e28dc9b5e43 127 Pfam PF08044 Domain of unknown function (DUF1707) 4 56 8.4E-19 T 28-03-2018 IPR012551 Protein of unknown function DUF1707 CU254_RS13950 802c5c6d70763c0df7252936e7c45624 221 Pfam PF11361 Protein of unknown function (DUF3159) 19 202 1.9E-9 T 28-03-2018 IPR016566 Uncharacterised conserved protein UCP010219 CU254_RS35380 4fc44df8f4321d333cb0c0d5221e1564 69 Pfam PF04024 PspC domain 11 68 6.8E-17 T 28-03-2018 IPR007168 Phage shock protein, PspC, N-terminal CU254_RS33285 e3a402dd5270c7aa55ed569993392644 390 TIGRFAM TIGR03934 TQXA_dom: TQXA domain 118 168 1.6E-11 T 28-03-2018 IPR023849 Uncharacterised domain CHP03934, TQXA CU254_RS24855 63e9a19be5a45dc307720c76ff554a01 158 Pfam PF04138 GtrA-like protein 36 149 4.8E-12 T 28-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 CU254_RS31150 067e6769555ad7f379a7da66a097ee40 152 Gene3D G3DSA:1.20.1250.20 6 137 2.5E-4 T 28-03-2018 CU254_RS24995 7e6c365fcdccd16b4fc438dbed39706c 209 Gene3D G3DSA:1.10.3630.10 4 182 3.9E-20 T 28-03-2018 CU254_RS24995 7e6c365fcdccd16b4fc438dbed39706c 209 Pfam PF05719 Golgi phosphoprotein 3 (GPP34) 6 192 5.1E-23 T 28-03-2018 IPR008628 Golgi phosphoprotein 3-like GO:0070273 CU254_RS31545 2475757a6671222bb94095b55ca05de8 162 SUPERFAMILY SSF103473 5 138 9.55E-5 T 28-03-2018 IPR020846 Major facilitator superfamily domain CU254_RS02925 a1b87982cf76cb00a7825f3dce374eec 187 Pfam PF13160 Protein of unknown function (DUF3995) 21 146 1.2E-14 T 28-03-2018 IPR025058 Protein of unknown function DUF3995 CU254_RS04605 a8e5afa891b49fa7497d3944bb75e1ad 104 Gene3D G3DSA:3.10.350.10 42 91 0.001 T 28-03-2018 CU254_RS40730 1291f0426e3ada96873227d641893862 121 Gene3D G3DSA:3.10.180.10 1 121 3.5E-16 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS40730 1291f0426e3ada96873227d641893862 121 SUPERFAMILY SSF54593 3 120 5.21E-15 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CU254_RS36650 4130c70729390c8e61c22759dd45e399 240 Pfam PF01988 VIT family 25 232 2.7E-57 T 28-03-2018 IPR008217 Ccc1 family CU254_RS37505 5817c27028af839ae7658d824ec456ad 139 Gene3D G3DSA:3.90.1530.10 45 138 0.0022 T 28-03-2018 CU254_RS32700 e549439c01372c8f26d2ebc7da832637 292 Pfam PF12679 ABC-2 family transporter protein 23 232 7.4E-13 T 28-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 CU254_RS13745 cd33dccfd307813cb2e0d6afe6372acc 130 Pfam PF14430 Immunity protein Imm1 14 129 1.3E-8 T 28-03-2018 IPR025680 Immunity protein Imm1 CU254_RS27100 c59537ae072a554756f15184fc63c288 89 Pfam PF04149 Domain of unknown function (DUF397) 30 83 1.3E-17 T 28-03-2018 IPR007278 Domain of unknown function DUF397 CU254_RS40420 be4d07a0005952d63bcf18ce2b0e5d72 390 Gene3D G3DSA:1.10.287.1060 28 120 6.2E-5 T 28-03-2018 CU254_RS15900 2e3824c3b3218e0ade298e44f0a986cb 137 Pfam PF14325 Domain of unknown function (DUF4383) 13 129 2.2E-26 T 28-03-2018 IPR025492 Protein of unknown function DUF4383 CU254_RS38885 e410e005714804413b58133204fc296b 133 Pfam PF17249 Family of unknown function (DUF5318) 1 130 7.4E-67 T 28-03-2018 IPR035169 Protein of unknown function DUF5318 CU254_RS10865 7cbe2fbfab5ef7e6669db7f3e39c3360 227 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 85 172 2.8E-11 T 28-03-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain CU254_RS04115 918d252f462ec236e89f250a130875c7 322 Pfam PF04228 Putative neutral zinc metallopeptidase 131 314 8.9E-15 T 28-03-2018 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative CU254_RS11660 6695fd94daf4a9bfedb3cd8dbaf61134 267 Gene3D G3DSA:1.10.10.10 132 225 0.003 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CU254_RS05400 0904276900ca3909c87b872a89d9ffba 254 Pfam PF01925 Sulfite exporter TauE/SafE 9 248 1.3E-34 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CU254_RS20515 58ac58b07abf76fd09e08463b6a878a3 173 Pfam PF07485 Domain of Unknown Function (DUF1259) 65 157 6.1E-26 T 28-03-2018 IPR011094 Uncharacterised protein family, LppY/LpqO CU254_RS06390 0ebbd92d36c1d7d119ffbc3cf26d5144 116 Pfam PF04341 Protein of unknown function, DUF485 20 105 2.9E-34 T 28-03-2018 IPR007436 Protein of unknown function DUF485 CU254_RS09475 f9578f307aa03d7d57fe2ca2bd56456f 562 Pfam PF05960 Bacterial protein of unknown function (DUF885) 27 558 2.2E-163 T 28-03-2018 IPR010281 Protein of unknown function DUF885 CU254_RS40915 4ba8505f5442395cbd29b165704b3f28 350 Gene3D G3DSA:1.10.260.40 60 158 1.4E-4 T 28-03-2018 CU254_RS06200 01f84cdf7decb196a0350d07b6b1e22d 363 Pfam PF06224 Winged helix DNA-binding domain 30 349 6.8E-78 T 28-03-2018 IPR009351 Protein of unknown function DUF1006 CU254_RS20365 9e7402b414cbdb87c896449d5073a04d 308 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 15 249 1.4E-52 T 28-03-2018 IPR018713 Domain of unknown function DUF2236 CU254_RS24545 afc819ceaead2505508ab3af88a06717 261 Pfam PF06966 Protein of unknown function (DUF1295) 22 247 2.0E-66 T 28-03-2018 IPR010721 Protein of unknown function DUF1295 CU254_RS01515 d4066393a7ab4de3364e7896cbcfa197 149 Pfam PF10861 Protein of Unknown function (DUF2784) 4 108 1.1E-23 T 28-03-2018 IPR021218 Protein of unknown function DUF2784 CU254_RS04745 cdd142aff02a7cec6ec31e8d0fa91af0 242 Pfam PF13829 Domain of unknown function (DUF4191) 19 233 3.2E-84 T 28-03-2018 IPR025445 Protein of unknown function DUF4191 CU254_RS04745 cdd142aff02a7cec6ec31e8d0fa91af0 242 ProDom PD037701 MEMBRANE INTEGRAL TRANSMEMBRANE RV2219/MT2276 NARROWLY PROBABLE PRECURSOR SIGNAL MLCB22.21 27 217 4.0E-58 T 28-03-2018 CU254_RS31990 5822900ddf146fab21354e96ffc6ddff 155 Pfam PF14081 Domain of unknown function (DUF4262) 23 141 1.6E-25 T 28-03-2018 IPR025358 Protein of unknown function DUF4262 CU254_RS12120 e9e1cc065b3efb072947b8cc1ad2b069 174 Gene3D G3DSA:2.60.20.10 87 163 2.0E-4 T 28-03-2018 CU254_RS16740 dcc35036dfff73a25f1aeb338020607c 703 Gene3D G3DSA:3.40.50.1110 469 698 4.5E-10 T 28-03-2018 CU254_RS16740 dcc35036dfff73a25f1aeb338020607c 703 Pfam PF01757 Acyltransferase family 26 331 9.7E-27 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CU254_RS09710 6d1536205708711e45fbe552ffcc6a5e 437 Pfam PF03993 Domain of Unknown Function (DUF349) 139 198 7.7E-12 T 28-03-2018 IPR007139 Protein of unknown function DUF349 CU254_RS09710 6d1536205708711e45fbe552ffcc6a5e 437 Pfam PF03993 Domain of Unknown Function (DUF349) 202 274 6.3E-23 T 28-03-2018 IPR007139 Protein of unknown function DUF349 CU254_RS09710 6d1536205708711e45fbe552ffcc6a5e 437 Pfam PF03993 Domain of Unknown Function (DUF349) 279 352 2.7E-20 T 28-03-2018 IPR007139 Protein of unknown function DUF349 CU254_RS41345 7104d347b33647375c60858156500cce 227 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 55 206 8.6E-7 T 28-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal CU254_RS14665 3881eb321d6bb0d8f8d2a1982f943779 281 Gene3D G3DSA:2.60.120.40 129 268 3.2E-6 T 28-03-2018 IPR008983 Tumour necrosis factor-like domain GO:0005515 CU254_RS42560 e2c94b788530eb434abda8c08b4a6668 196 Gene3D G3DSA:3.40.50.1010 1 124 3.2E-4 T 28-03-2018 IPR029060 PIN domain-like CU254_RS22095 a763986523ad922b8a5071bd2f45d2ac 147 Gene3D G3DSA:1.10.260.40 5 98 2.5E-13 T 28-03-2018