locus-tag	class	description
HUT10_RS00010	COG2249	NAD(P)H dehydrogenase (quinone) activity
HUT10_RS00015	COG2367	Beta-lactamase
HUT10_RS00045	COG0709	Synthesizes selenophosphate from selenide and ATP
HUT10_RS00055	COG1921	L-seryl-tRNASec selenium transferase activity
HUT10_RS00070	COG4221	oxidoreductase activity
HUT10_RS00075	COG0596	Alpha beta hydrolase
HUT10_RS00100	COG3250	beta-galactosidase activity
HUT10_RS00115	COG2197	response regulator
HUT10_RS00120	COG4585	Histidine kinase
HUT10_RS00125	COG0463	Glycosyl transferase, family 2
HUT10_RS00130	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HUT10_RS00140	COG3293	Transposase
HUT10_RS00150	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HUT10_RS00195	COG4941	Belongs to the sigma-70 factor family
HUT10_RS00225	COG0515	serine threonine protein kinase
HUT10_RS00230	COG3321	synthase
HUT10_RS00230	COG0604	alcohol dehydrogenase
HUT10_RS00230	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS00235	COG0789	Transcriptional regulator
HUT10_RS00265	COG0784	Response regulator, receiver
HUT10_RS00310	COG0300	oxidoreductase activity
HUT10_RS00340	COG4221	oxidoreductase activity
HUT10_RS00350	COG1879	ABC-type sugar transport system periplasmic component
HUT10_RS00370	COG0346	lactoylglutathione lyase activity
HUT10_RS00375	COG0400	carboxylic ester hydrolase activity
HUT10_RS00380	COG2770	Histidine kinase
HUT10_RS00380	COG2208	phosphoserine phosphatase activity
HUT10_RS00395	COG0577	efflux transmembrane transporter activity
HUT10_RS00395	COG1136	(ABC) transporter
HUT10_RS00405	COG4585	Histidine kinase
HUT10_RS00410	COG2197	response regulator
HUT10_RS00450	COG0488	(ABC) transporter
HUT10_RS00455	COG0395	ABC-type sugar transport system, permease component
HUT10_RS00480	COG3486	L-lysine 6-monooxygenase (NADPH) activity
HUT10_RS00490	COG2318	DinB family
HUT10_RS00495	COG1120	ATPase activity
HUT10_RS00500	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT10_RS00505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT10_RS00515	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HUT10_RS00535	COG1132	(ABC) transporter
HUT10_RS00540	COG1132	(ABC) transporter
HUT10_RS00565	COG0583	DNA-binding transcription factor activity
HUT10_RS00585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUT10_RS00590	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUT10_RS00595	COG1116	anion transmembrane transporter activity
HUT10_RS00630	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_RS00635	COG2211	Major facilitator Superfamily
HUT10_RS00640	COG0076	glutamate decarboxylase activity
HUT10_RS00660	COG2814	Major facilitator Superfamily
HUT10_RS00680	COG0523	cobalamin synthesis protein
HUT10_RS00700	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HUT10_RS00705	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HUT10_RS00710	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HUT10_RS00715	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HUT10_RS00745	COG1024	Enoyl-CoA hydratase
HUT10_RS00750	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUT10_RS00780	COG1716	ATPase activity
HUT10_RS00795	COG0789	Transcriptional regulator
HUT10_RS00800	COG3118	belongs to the thioredoxin family
HUT10_RS00800	COG0492	ferredoxin-NADP+ reductase activity
HUT10_RS00815	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HUT10_RS00815	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HUT10_RS00835	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HUT10_RS00880	COG1309	transcriptional regulator
HUT10_RS00905	COG2267	carboxylic ester hydrolase activity
HUT10_RS00910	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HUT10_RS00915	COG0583	DNA-binding transcription factor activity
HUT10_RS00920	COG3572	ergothioneine biosynthetic process
HUT10_RS00925	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HUT10_RS00935	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
HUT10_RS00950	COG1285	pathogenesis
HUT10_RS00955	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HUT10_RS00960	COG0791	NLP P60 protein
HUT10_RS00960	COG3883	PFAM NLP P60 protein
HUT10_RS00965	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HUT10_RS00970	COG0746	molybdenum cofactor guanylyltransferase activity
HUT10_RS00975	COG0714	Associated with various cellular activities
HUT10_RS00985	COG2304	oxidoreductase activity
HUT10_RS00995	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HUT10_RS01010	COG2205	protein histidine kinase activity
HUT10_RS01015	COG0745	RESPONSE REGULATOR receiver
HUT10_RS01020	COG0477	Major facilitator Superfamily
HUT10_RS01030	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HUT10_RS01050	COG4106	trans-aconitate 2-methyltransferase activity
HUT10_RS01060	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
HUT10_RS01070	COG0215	cysteine-tRNA ligase activity
HUT10_RS01075	COG0488	(ABC) transporter
HUT10_RS01115	COG0646	methionine synthase
HUT10_RS01115	COG1410	methionine synthase
HUT10_RS01120	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUT10_RS01135	COG0140	phosphoribosyl-ATP diphosphatase activity
HUT10_RS01140	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
HUT10_RS01150	COG1192	Involved in chromosome partitioning
HUT10_RS01165	COG0517	IMP dehydrogenase activity
HUT10_RS01165	COG1994	Peptidase M50
HUT10_RS01185	COG1222	aaa ATPase
HUT10_RS01205	COG0640	Transcriptional regulator
HUT10_RS01240	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
HUT10_RS01245	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
HUT10_RS01260	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
HUT10_RS01270	COG4221	oxidoreductase activity
HUT10_RS01280	COG1733	regulation of RNA biosynthetic process
HUT10_RS01290	COG2378	regulation of single-species biofilm formation
HUT10_RS01300	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HUT10_RS01310	COG1597	lipid kinase activity
HUT10_RS01365	COG2814	Major facilitator Superfamily
HUT10_RS01380	COG1309	transcriptional regulator
HUT10_RS01385	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HUT10_RS01390	COG0583	DNA-binding transcription factor activity
HUT10_RS01395	COG4221	oxidoreductase activity
HUT10_RS01415	COG1136	(ABC) transporter
HUT10_RS01420	COG1136	(ABC) transporter
HUT10_RS01430	COG3979	chitinase
HUT10_RS01450	COG3485	protocatechuate 3,4-dioxygenase
HUT10_RS01460	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUT10_RS01465	COG1414	Transcriptional regulator
HUT10_RS01470	COG0402	S-adenosylhomocysteine deaminase activity
HUT10_RS01505	COG1222	aaa ATPase
HUT10_RS01605	COG2197	response regulator
HUT10_RS01610	COG2197	response regulator
HUT10_RS01620	COG1024	Enoyl-CoA hydratase
HUT10_RS01620	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HUT10_RS01625	COG3693	PFAM glycoside hydrolase, family 10
HUT10_RS01675	COG1181	Belongs to the D-alanine--D-alanine ligase family
HUT10_RS01680	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT10_RS01715	COG0277	FAD linked oxidase domain protein
HUT10_RS01725	COG1834	amidinotransferase
HUT10_RS01785	COG0189	ligase activity
HUT10_RS01805	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HUT10_RS01810	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HUT10_RS01870	COG3285	dna ligase
HUT10_RS01870	COG1793	dna ligase
HUT10_RS01880	COG1105	Belongs to the carbohydrate kinase PfkB family
HUT10_RS01895	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUT10_RS01900	COG1063	alcohol dehydrogenase
HUT10_RS01905	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HUT10_RS01910	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUT10_RS01975	COG0604	alcohol dehydrogenase
HUT10_RS01975	COG3321	synthase
HUT10_RS01985	COG3959	Transketolase, thiamine diphosphate binding domain
HUT10_RS02110	COG0604	alcohol dehydrogenase
HUT10_RS02110	COG3321	synthase
HUT10_RS02140	COG1819	glycosyl
HUT10_RS02145	COG1349	DNA-binding transcription factor activity
HUT10_RS02160	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HUT10_RS02170	COG0463	Glycosyl transferase, family 2
HUT10_RS02175	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HUT10_RS02185	COG0494	nUDIX hydrolase
HUT10_RS02195	COG1435	thymidine kinase activity
HUT10_RS02230	COG0640	Transcriptional regulator
HUT10_RS02245	COG1396	sequence-specific DNA binding
HUT10_RS02260	COG1309	transcriptional regulator
HUT10_RS02265	COG1960	acyl-CoA dehydrogenase activity
HUT10_RS02275	COG1309	transcriptional regulator
HUT10_RS02310	COG2124	cytochrome p450
HUT10_RS02320	COG4941	Belongs to the sigma-70 factor family
HUT10_RS02370	COG4941	Belongs to the sigma-70 factor family
HUT10_RS02400	COG2226	methyltransferase
HUT10_RS02455	COG0477	Major facilitator Superfamily
HUT10_RS02495	COG0823	Involved in the tonB-independent uptake of proteins
HUT10_RS02495	COG4946	Tricorn protease homolog
HUT10_RS02495	COG1506	peptidase
HUT10_RS02500	COG1619	proteins homologs of microcin C7 resistance protein MccF
HUT10_RS02525	COG0601	transmembrane transport
HUT10_RS02535	COG2362	D-Aminopeptidase
HUT10_RS02540	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUT10_RS02570	COG3537	Alpha-1,2-mannosidase
HUT10_RS02590	COG0039	L-malate dehydrogenase activity
HUT10_RS02595	COG0740	serine-type endopeptidase activity
HUT10_RS02610	COG1968	undecaprenyl-diphosphatase activity
HUT10_RS02615	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_RS02620	COG0667	Aldo Keto reductase
HUT10_RS02655	COG2267	carboxylic ester hydrolase activity
HUT10_RS02660	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUT10_RS02670	COG1609	Transcriptional regulator
HUT10_RS02680	COG2301	Belongs to the HpcH HpaI aldolase family
HUT10_RS02695	COG0583	DNA-binding transcription factor activity
HUT10_RS02730	COG1793	dna ligase
HUT10_RS02730	COG3285	dna ligase
HUT10_RS02755	COG0596	Alpha beta hydrolase
HUT10_RS02760	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUT10_RS02775	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HUT10_RS02785	COG2066	Belongs to the glutaminase family
HUT10_RS02850	COG2252	PERMEase
HUT10_RS02855	COG0590	tRNA wobble adenosine to inosine editing
HUT10_RS02875	COG3960	tartronate-semialdehyde synthase activity
HUT10_RS02880	COG2084	Dehydrogenase
HUT10_RS02885	COG3622	Belongs to the hyi family
HUT10_RS02895	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HUT10_RS02900	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HUT10_RS02930	COG1278	Cold shock
HUT10_RS02950	COG3250	beta-galactosidase activity
HUT10_RS02965	COG1070	Carbohydrate kinase
HUT10_RS02975	COG3347	Dehydrogenase
HUT10_RS02975	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS02985	COG3254	rhamnose metabolic process
HUT10_RS03000	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUT10_RS03010	COG1609	Transcriptional regulator
HUT10_RS03025	COG3903	Transcriptional regulator
HUT10_RS03025	COG3629	intracellular signal transduction
HUT10_RS03065	COG0028	Belongs to the TPP enzyme family
HUT10_RS03070	COG0583	DNA-binding transcription factor activity
HUT10_RS03075	COG0387	Pfam Sodium calcium exchanger
HUT10_RS03085	COG3850	Histidine kinase
HUT10_RS03085	COG4999	Histidine kinase
HUT10_RS03085	COG2205	protein histidine kinase activity
HUT10_RS03085	COG3437	response regulator, receiver
HUT10_RS03095	COG0823	Involved in the tonB-independent uptake of proteins
HUT10_RS03095	COG1506	peptidase
HUT10_RS03095	COG4946	Tricorn protease homolog
HUT10_RS03120	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HUT10_RS03125	COG1278	Cold shock
HUT10_RS03145	COG1609	Transcriptional regulator
HUT10_RS03155	COG0395	ABC-type sugar transport system, permease component
HUT10_RS03160	COG1175	transmembrane transport
HUT10_RS03170	COG1609	Transcriptional regulator
HUT10_RS03230	COG2267	carboxylic ester hydrolase activity
HUT10_RS03245	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HUT10_RS03255	COG3285	dna ligase
HUT10_RS03255	COG1793	dna ligase
HUT10_RS03300	COG0477	Major facilitator Superfamily
HUT10_RS03305	COG3046	protein related to deoxyribodipyrimidine photolyase
HUT10_RS03355	COG3250	beta-galactosidase activity
HUT10_RS03380	COG0297	glycogen (starch) synthase activity
HUT10_RS03395	COG3629	intracellular signal transduction
HUT10_RS03395	COG3903	Transcriptional regulator
HUT10_RS03415	COG1090	epimerase
HUT10_RS03475	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
HUT10_RS03490	COG3629	intracellular signal transduction
HUT10_RS03490	COG3903	Transcriptional regulator
HUT10_RS03525	COG0673	inositol 2-dehydrogenase activity
HUT10_RS03540	COG0395	ABC-type sugar transport system, permease component
HUT10_RS03545	COG1175	transmembrane transport
HUT10_RS03550	COG1653	transport
HUT10_RS03560	COG1609	Transcriptional regulator
HUT10_RS03565	COG0277	FAD linked oxidase domain protein
HUT10_RS03625	COG0604	alcohol dehydrogenase
HUT10_RS03630	COG0137	argininosuccinate synthase activity
HUT10_RS03645	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HUT10_RS03650	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HUT10_RS03660	COG1414	Transcriptional regulator
HUT10_RS03665	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HUT10_RS03690	COG1609	Transcriptional regulator
HUT10_RS03700	COG4214	carbohydrate transport
HUT10_RS03705	COG1129	ABC transporter
HUT10_RS03715	COG2160	L-arabinose isomerase activity
HUT10_RS03735	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUT10_RS03740	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUT10_RS03750	COG1879	ABC-type sugar transport system periplasmic component
HUT10_RS03765	COG1686	Belongs to the peptidase S11 family
HUT10_RS03780	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS03795	COG1470	cell adhesion involved in biofilm formation
HUT10_RS03795	COG0366	Alpha amylase catalytic
HUT10_RS03800	COG1609	Transcriptional regulator
HUT10_RS03825	COG0302	gtp cyclohydrolase
HUT10_RS03890	COG4991	sh3 domain protein
HUT10_RS03895	COG1472	Belongs to the glycosyl hydrolase 3 family
HUT10_RS03900	COG0395	ABC-type sugar transport system, permease component
HUT10_RS03905	COG1175	transmembrane transport
HUT10_RS03910	COG2182	Extracellular solute-binding protein
HUT10_RS03920	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HUT10_RS03930	COG0477	Major facilitator Superfamily
HUT10_RS03945	COG2181	nitrate reductase activity
HUT10_RS03945	COG0247	lactate metabolic process
HUT10_RS03960	COG1716	ATPase activity
HUT10_RS03960	COG5001	Diguanylate cyclase
HUT10_RS03970	COG2124	cytochrome p450
HUT10_RS03980	COG1472	Belongs to the glycosyl hydrolase 3 family
HUT10_RS03985	COG1609	Transcriptional regulator
HUT10_RS03995	COG1175	transmembrane transport
HUT10_RS04000	COG0395	ABC-type sugar transport system, permease component
HUT10_RS04015	COG1309	transcriptional regulator
HUT10_RS04020	COG2353	YceI-like domain
HUT10_RS04025	COG1846	Transcriptional regulator
HUT10_RS04030	COG0435	Glutathione S-transferase
HUT10_RS04040	COG0596	Alpha beta hydrolase
HUT10_RS04060	COG0459	protein refolding
HUT10_RS04065	COG1063	alcohol dehydrogenase
HUT10_RS04105	COG3284	Transcriptional regulator
HUT10_RS04130	COG3835	regulator
HUT10_RS04155	COG0596	Alpha beta hydrolase
HUT10_RS04220	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
HUT10_RS04230	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
HUT10_RS04245	COG2890	protein-(glutamine-N5) methyltransferase activity
HUT10_RS04255	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HUT10_RS04270	COG0300	oxidoreductase activity
HUT10_RS04290	COG1295	ribonuclease BN
HUT10_RS04290	COG1959	2 iron, 2 sulfur cluster binding
HUT10_RS04310	COG2936	dipeptidyl-peptidase activity
HUT10_RS04335	COG0297	glycogen (starch) synthase activity
HUT10_RS04340	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HUT10_RS04340	COG0463	Glycosyl transferase, family 2
HUT10_RS04360	COG2192	nodulation
HUT10_RS04365	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
HUT10_RS04370	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
HUT10_RS04370	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
HUT10_RS04375	COG0300	oxidoreductase activity
HUT10_RS04385	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HUT10_RS04405	COG1012	belongs to the aldehyde dehydrogenase family
HUT10_RS04410	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
HUT10_RS04415	COG0859	PFAM glycosyl transferase family 9
HUT10_RS04425	COG0248	Ppx GppA phosphatase
HUT10_RS04435	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS04480	COG0326	Molecular chaperone. Has ATPase activity
HUT10_RS04540	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HUT10_RS04560	COG2890	protein-(glutamine-N5) methyltransferase activity
HUT10_RS04570	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HUT10_RS04610	COG2267	carboxylic ester hydrolase activity
HUT10_RS04640	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HUT10_RS04660	COG3634	alkyl hydroperoxide reductase activity
HUT10_RS04675	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HUT10_RS04680	COG1846	Transcriptional regulator
HUT10_RS04680	COG0456	acetyltransferase
HUT10_RS04750	COG3285	dna ligase
HUT10_RS04750	COG1793	dna ligase
HUT10_RS04810	COG4106	trans-aconitate 2-methyltransferase activity
HUT10_RS04835	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_RS04860	COG0477	Major facilitator Superfamily
HUT10_RS04900	COG0439	Biotin carboxylase
HUT10_RS04925	COG0583	DNA-binding transcription factor activity
HUT10_RS04935	COG2855	membrane
HUT10_RS04950	COG4585	Histidine kinase
HUT10_RS04955	COG2197	response regulator
HUT10_RS04975	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HUT10_RS05005	COG1793	dna ligase
HUT10_RS05010	COG2318	DinB family
HUT10_RS05025	COG0477	Major facilitator Superfamily
HUT10_RS05045	COG3629	intracellular signal transduction
HUT10_RS05045	COG3903	Transcriptional regulator
HUT10_RS05060	COG1846	Transcriptional regulator
HUT10_RS05090	COG2124	cytochrome p450
HUT10_RS05105	COG1609	Transcriptional regulator
HUT10_RS05130	COG0531	amino acid
HUT10_RS05135	COG1940	carbohydrate kinase activity
HUT10_RS05180	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HUT10_RS05185	COG1309	transcriptional regulator
HUT10_RS05215	COG1063	alcohol dehydrogenase
HUT10_RS05230	COG3591	Belongs to the peptidase S1B family
HUT10_RS05230	COG1864	DNA RNA non-specific endonuclease
HUT10_RS05235	COG1802	Transcriptional regulator
HUT10_RS05250	COG1960	acyl-CoA dehydrogenase activity
HUT10_RS05255	COG1960	acyl-CoA dehydrogenase activity
HUT10_RS05265	COG1024	Enoyl-CoA hydratase
HUT10_RS05270	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_RS05275	COG1960	acyl-CoA dehydrogenase activity
HUT10_RS05280	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS05285	COG0183	Belongs to the thiolase family
HUT10_RS05290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_RS05310	COG1024	Enoyl-CoA hydratase
HUT10_RS05315	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS05350	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUT10_RS05365	COG0477	Major facilitator Superfamily
HUT10_RS05370	COG2409	Drug exporters of the RND superfamily
HUT10_RS05395	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUT10_RS05400	COG0484	heat shock protein binding
HUT10_RS05405	COG1280	lysine exporter protein (LysE YggA)
HUT10_RS05435	COG2357	RelA SpoT domain protein
HUT10_RS05485	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HUT10_RS05490	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HUT10_RS05495	COG2080	2 iron, 2 sulfur cluster binding
HUT10_RS05505	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUT10_RS05525	COG3591	Belongs to the peptidase S1B family
HUT10_RS05560	COG3706	GGDEF domain
HUT10_RS05570	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HUT10_RS05580	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HUT10_RS05590	COG2182	Extracellular solute-binding protein
HUT10_RS05595	COG1175	transmembrane transport
HUT10_RS05600	COG0395	ABC-type sugar transport system, permease component
HUT10_RS05610	COG2188	Transcriptional regulator
HUT10_RS05630	COG2018	Roadblock/LC7 domain
HUT10_RS05655	COG0028	Belongs to the TPP enzyme family
HUT10_RS05665	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS05680	COG1309	transcriptional regulator
HUT10_RS05775	COG2197	response regulator
HUT10_RS05805	COG1366	Belongs to the anti-sigma-factor antagonist family
HUT10_RS05830	COG1024	Enoyl-CoA hydratase
HUT10_RS05835	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUT10_RS05885	COG1793	dna ligase
HUT10_RS05885	COG3285	dna ligase
HUT10_RS05895	COG3507	Belongs to the glycosyl hydrolase 43 family
HUT10_RS05950	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HUT10_RS05960	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUT10_RS05970	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUT10_RS05970	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUT10_RS05980	COG3938	Belongs to the proline racemase family
HUT10_RS05985	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUT10_RS06015	COG3511	phospholipase C
HUT10_RS06020	COG1846	Transcriptional regulator
HUT10_RS06045	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HUT10_RS06050	COG1053	succinate dehydrogenase
HUT10_RS06060	COG0583	DNA-binding transcription factor activity
HUT10_RS06065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_RS06100	COG2318	DinB family
HUT10_RS06115	COG2271	Major facilitator Superfamily
HUT10_RS06120	COG0243	molybdopterin cofactor binding
HUT10_RS06125	COG3383	formate dehydrogenase (NAD+) activity
HUT10_RS06125	COG0243	molybdopterin cofactor binding
HUT10_RS06130	COG0437	4 iron, 4 sulfur cluster binding
HUT10_RS06155	COG1609	Transcriptional regulator
HUT10_RS06160	COG1349	DNA-binding transcription factor activity
HUT10_RS06175	COG1175	transmembrane transport
HUT10_RS06180	COG0395	ABC-type sugar transport system, permease component
HUT10_RS06225	COG1595	DNA-templated transcription, initiation
HUT10_RS06230	COG0366	Alpha amylase catalytic
HUT10_RS06270	COG0477	Major facilitator Superfamily
HUT10_RS06275	COG0628	permease
HUT10_RS06320	COG0477	Major facilitator Superfamily
HUT10_RS06325	COG3387	PFAM Glycoside hydrolase 15-related
HUT10_RS06340	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUT10_RS06370	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HUT10_RS06400	COG1960	acyl-CoA dehydrogenase activity
HUT10_RS06405	COG1960	acyl-CoA dehydrogenase activity
HUT10_RS06410	COG1960	acyl-CoA dehydrogenase activity
HUT10_RS06420	COG0596	Alpha beta hydrolase
HUT10_RS06430	COG1309	transcriptional regulator
HUT10_RS06440	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_RS06450	COG3250	beta-galactosidase activity
HUT10_RS06465	COG1131	(ABC) transporter
HUT10_RS06485	COG5002	protein histidine kinase activity
HUT10_RS06490	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HUT10_RS06495	COG4948	Mandelate Racemase Muconate Lactonizing
HUT10_RS06500	COG0395	ABC-type sugar transport system, permease component
HUT10_RS06510	COG2186	Transcriptional regulator
HUT10_RS06515	COG4948	Mandelate Racemase Muconate Lactonizing
HUT10_RS06525	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_RS06530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_RS06610	COG2222	sugar isomerase
HUT10_RS06615	COG1349	DNA-binding transcription factor activity
HUT10_RS06635	COG0395	ABC-type sugar transport system, permease component
HUT10_RS06640	COG1486	melibiose metabolic process
HUT10_RS06650	COG3345	alpha-galactosidase
HUT10_RS06660	COG0583	DNA-binding transcription factor activity
HUT10_RS06665	COG0438	transferase activity, transferring glycosyl groups
HUT10_RS06680	COG2144	transferase activity, transferring acyl groups
HUT10_RS06700	COG2072	flavoprotein involved in K transport
HUT10_RS06715	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HUT10_RS06730	COG2205	protein histidine kinase activity
HUT10_RS06740	COG0531	amino acid
HUT10_RS06785	COG1073	alpha beta
HUT10_RS06790	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS06795	COG0179	Fumarylacetoacetate (FAA) hydrolase
HUT10_RS06805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT10_RS06835	COG1595	DNA-templated transcription, initiation
HUT10_RS06860	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUT10_RS06865	COG1129	ABC transporter
HUT10_RS06900	COG1309	transcriptional regulator
HUT10_RS06920	COG2197	response regulator
HUT10_RS06925	COG4585	Histidine kinase
HUT10_RS06950	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HUT10_RS06955	COG0640	Transcriptional regulator
HUT10_RS06970	COG0693	protein deglycase activity
HUT10_RS06975	COG1063	alcohol dehydrogenase
HUT10_RS07015	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_RS07020	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_RS07025	COG0583	DNA-binding transcription factor activity
HUT10_RS07090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUT10_RS07100	COG1116	anion transmembrane transporter activity
HUT10_RS07105	COG1053	succinate dehydrogenase
HUT10_RS07145	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
HUT10_RS07155	COG4948	Mandelate Racemase Muconate Lactonizing
HUT10_RS07160	COG3485	protocatechuate 3,4-dioxygenase
HUT10_RS07175	COG1414	Transcriptional regulator
HUT10_RS07195	COG1309	transcriptional regulator
HUT10_RS07210	COG1309	transcriptional regulator
HUT10_RS07225	COG3321	synthase
HUT10_RS07225	COG0604	alcohol dehydrogenase
HUT10_RS07230	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HUT10_RS07310	COG1064	alcohol dehydrogenase
HUT10_RS07475	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_RS07480	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS07485	COG1309	transcriptional regulator
HUT10_RS07505	COG4221	oxidoreductase activity
HUT10_RS07540	COG1659	Linocin_M18 bacteriocin protein
HUT10_RS07590	COG0477	Major facilitator Superfamily
HUT10_RS07605	COG1309	transcriptional regulator
HUT10_RS07615	COG0745	RESPONSE REGULATOR receiver
HUT10_RS07640	COG1819	glycosyl
HUT10_RS07680	COG4221	oxidoreductase activity
HUT10_RS07710	COG1802	Transcriptional regulator
HUT10_RS07725	COG0473	3-isopropylmalate dehydrogenase activity
HUT10_RS07730	COG0583	DNA-binding transcription factor activity
HUT10_RS07735	COG0667	Aldo Keto reductase
HUT10_RS07740	COG1309	transcriptional regulator
HUT10_RS07745	COG0133	tryptophan synthase activity
HUT10_RS07750	COG0159	tryptophan synthase activity
HUT10_RS07760	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS07770	COG0477	Major facilitator Superfamily
HUT10_RS07795	COG3942	CHAP domain
HUT10_RS07795	COG1388	LysM domain
HUT10_RS07860	COG1574	metal-dependent hydrolase with the TIM-barrel fold
HUT10_RS07885	COG0747	negative chemotaxis
HUT10_RS07890	COG0601	transmembrane transport
HUT10_RS07910	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS07915	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HUT10_RS07920	COG1063	alcohol dehydrogenase
HUT10_RS07950	COG0179	Fumarylacetoacetate (FAA) hydrolase
HUT10_RS07955	COG1802	Transcriptional regulator
HUT10_RS07960	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUT10_RS07975	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HUT10_RS08080	COG2197	response regulator
HUT10_RS08135	COG1302	Protein conserved in bacteria
HUT10_RS08170	COG0009	L-threonylcarbamoyladenylate synthase
HUT10_RS08190	COG3209	COG3209 Rhs family protein
HUT10_RS08190	COG3209	COG3209 Rhs family protein
HUT10_RS08195	COG1902	pentaerythritol trinitrate reductase activity
HUT10_RS08200	COG2267	carboxylic ester hydrolase activity
HUT10_RS08210	COG2843	Capsule synthesis protein
HUT10_RS08220	COG1473	amidohydrolase
HUT10_RS08225	COG0477	Major facilitator Superfamily
HUT10_RS08235	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
HUT10_RS08250	COG1960	acyl-CoA dehydrogenase activity
HUT10_RS08275	COG2197	response regulator
HUT10_RS08280	COG3629	intracellular signal transduction
HUT10_RS08280	COG3903	Transcriptional regulator
HUT10_RS08285	COG1414	Transcriptional regulator
HUT10_RS08290	COG3971	2-oxopent-4-enoate hydratase activity
HUT10_RS08295	COG4569	acetaldehyde dehydrogenase (acetylating) activity
HUT10_RS08300	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HUT10_RS08395	COG3511	phospholipase C
HUT10_RS08430	COG1846	Transcriptional regulator
HUT10_RS08445	COG3629	intracellular signal transduction
HUT10_RS08445	COG3903	Transcriptional regulator
HUT10_RS08450	COG0477	Major facilitator Superfamily
HUT10_RS08465	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_RS08475	COG1024	Enoyl-CoA hydratase
HUT10_RS08485	COG0492	ferredoxin-NADP+ reductase activity
HUT10_RS08495	COG3384	dioxygenase
HUT10_RS08520	COG1414	Transcriptional regulator
HUT10_RS08525	COG2272	Belongs to the type-B carboxylesterase lipase family
HUT10_RS08555	COG3321	synthase
HUT10_RS08555	COG0604	alcohol dehydrogenase
HUT10_RS08570	COG5001	Diguanylate cyclase
HUT10_RS08600	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HUT10_RS08670	COG0642	Histidine kinase
HUT10_RS08670	COG3850	Histidine kinase
HUT10_RS08685	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HUT10_RS08705	COG1653	transport
HUT10_RS08730	COG0583	DNA-binding transcription factor activity
HUT10_RS08740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUT10_RS08750	COG1126	abc transporter atp-binding protein
HUT10_RS08775	COG0596	Alpha beta hydrolase
HUT10_RS08775	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUT10_RS08800	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS08870	COG3387	PFAM Glycoside hydrolase 15-related
HUT10_RS08885	COG1595	DNA-templated transcription, initiation
HUT10_RS08890	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUT10_RS08920	COG2255	four-way junction helicase activity
HUT10_RS08985	COG5492	domain, Protein
HUT10_RS08985	COG4932	domain protein
HUT10_RS09020	COG1595	DNA-templated transcription, initiation
HUT10_RS09120	COG0671	phosphoesterase, PA-phosphatase related
HUT10_RS09140	COG0366	Alpha amylase catalytic
HUT10_RS09145	COG1609	Transcriptional regulator
HUT10_RS09170	COG2508	Transcriptional regulator
HUT10_RS09175	COG1609	Transcriptional regulator
HUT10_RS09230	COG2409	Drug exporters of the RND superfamily
HUT10_RS09250	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HUT10_RS09255	COG1285	pathogenesis
HUT10_RS09265	COG1116	anion transmembrane transporter activity
HUT10_RS09340	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
HUT10_RS09345	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HUT10_RS09350	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HUT10_RS09370	COG0531	amino acid
HUT10_RS09500	COG2801	Transposase and inactivated derivatives
HUT10_RS09500	COG3415	Transposase
HUT10_RS09525	COG2175	clavaminate synthase activity
HUT10_RS09610	COG1674	ftsk spoiiie
HUT10_RS09620	COG3629	intracellular signal transduction
HUT10_RS09620	COG3903	Transcriptional regulator
HUT10_RS09645	COG0653	protein targeting
HUT10_RS09660	COG1404	Belongs to the peptidase S8 family
HUT10_RS09670	COG0464	growth
HUT10_RS09700	COG2197	response regulator
HUT10_RS09725	COG3903	Transcriptional regulator
HUT10_RS09725	COG3629	intracellular signal transduction
HUT10_RS09730	COG3903	Transcriptional regulator
HUT10_RS09730	COG3629	intracellular signal transduction
HUT10_RS09735	COG2197	response regulator
HUT10_RS09745	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
HUT10_RS09750	COG3903	Transcriptional regulator
HUT10_RS09750	COG3629	intracellular signal transduction
HUT10_RS09760	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS09785	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HUT10_RS09835	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_RS09855	COG2986	histidine ammonia-lyase
HUT10_RS09870	COG2132	Multicopper oxidase
HUT10_RS09905	COG0477	Major facilitator Superfamily
HUT10_RS09915	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HUT10_RS09925	COG0006	proline dipeptidase activity
HUT10_RS09935	COG2124	cytochrome p450
HUT10_RS09945	COG0300	oxidoreductase activity
HUT10_RS09970	COG2124	cytochrome p450
HUT10_RS09975	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_RS10010	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HUT10_RS10020	COG0477	Major facilitator Superfamily
HUT10_RS10030	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUT10_RS10075	COG2815	serine threonine protein kinase
HUT10_RS10075	COG0515	serine threonine protein kinase
HUT10_RS10145	COG0494	nUDIX hydrolase
HUT10_RS10275	COG0587	DNA-directed DNA polymerase activity
HUT10_RS10325	COG0587	DNA-directed DNA polymerase activity
HUT10_RS10405	COG3903	Transcriptional regulator
HUT10_RS10405	COG3629	intracellular signal transduction
HUT10_RS10410	COG3629	intracellular signal transduction
HUT10_RS10410	COG3903	Transcriptional regulator
HUT10_RS10465	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT10_RS10470	COG2192	nodulation
HUT10_RS10505	COG2986	histidine ammonia-lyase
HUT10_RS10540	COG3903	Transcriptional regulator
HUT10_RS10540	COG3629	intracellular signal transduction
HUT10_RS10770	COG1404	Belongs to the peptidase S8 family
HUT10_RS10880	COG2197	response regulator
HUT10_RS10900	COG3883	PFAM NLP P60 protein
HUT10_RS10900	COG0791	NLP P60 protein
HUT10_RS10990	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUT10_RS11080	COG3903	Transcriptional regulator
HUT10_RS11080	COG3629	intracellular signal transduction
HUT10_RS11085	COG3629	intracellular signal transduction
HUT10_RS11085	COG3903	Transcriptional regulator
HUT10_RS11105	COG0583	DNA-binding transcription factor activity
HUT10_RS11120	COG2814	Major facilitator Superfamily
HUT10_RS11155	COG0154	amidase activity
HUT10_RS11160	COG0789	Transcriptional regulator
HUT10_RS11165	COG0640	Transcriptional regulator
HUT10_RS11190	COG0673	inositol 2-dehydrogenase activity
HUT10_RS11215	COG1653	transport
HUT10_RS11245	COG1131	(ABC) transporter
HUT10_RS11250	COG1725	Transcriptional regulator
HUT10_RS11255	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
HUT10_RS11260	COG0028	Belongs to the TPP enzyme family
HUT10_RS11275	COG1522	sequence-specific DNA binding
HUT10_RS11285	COG2197	response regulator
HUT10_RS11300	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HUT10_RS11310	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HUT10_RS11320	COG0702	epimerase
HUT10_RS11335	COG0583	DNA-binding transcription factor activity
HUT10_RS11340	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HUT10_RS11410	COG0300	oxidoreductase activity
HUT10_RS11415	COG4221	oxidoreductase activity
HUT10_RS11420	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HUT10_RS11480	COG2318	DinB family
HUT10_RS11510	COG2267	carboxylic ester hydrolase activity
HUT10_RS11565	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HUT10_RS11610	COG0515	serine threonine protein kinase
HUT10_RS11610	COG2815	serine threonine protein kinase
HUT10_RS11620	COG0456	acetyltransferase
HUT10_RS11625	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HUT10_RS11655	COG3511	phospholipase C
HUT10_RS11730	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS11795	COG0714	Associated with various cellular activities
HUT10_RS11805	COG3552	Protein containing von Willebrand factor type A (VWA) domain
HUT10_RS11810	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HUT10_RS11820	COG1733	regulation of RNA biosynthetic process
HUT10_RS11830	COG5492	domain, Protein
HUT10_RS11845	COG4948	Mandelate Racemase Muconate Lactonizing
HUT10_RS11850	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUT10_RS11860	COG1414	Transcriptional regulator
HUT10_RS11865	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUT10_RS11945	COG1160	GTP binding
HUT10_RS11975	COG0475	glutathione-regulated potassium exporter activity
HUT10_RS11985	COG2936	dipeptidyl-peptidase activity
HUT10_RS11990	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HUT10_RS12000	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HUT10_RS12035	COG0504	CTP synthase activity
HUT10_RS12055	COG1953	Uracil, thiamine, allantoin
HUT10_RS12105	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HUT10_RS12120	COG0647	UMP catabolic process
HUT10_RS12145	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HUT10_RS12150	COG2094	Belongs to the DNA glycosylase MPG family
HUT10_RS12155	COG0165	Argininosuccinate lyase
HUT10_RS12165	COG1438	arginine binding
HUT10_RS12170	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HUT10_RS12175	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HUT10_RS12180	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HUT10_RS12185	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HUT10_RS12190	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HUT10_RS12205	COG0596	Alpha beta hydrolase
HUT10_RS12215	COG0072	phenylalanine-tRNA ligase activity
HUT10_RS12215	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HUT10_RS12220	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HUT10_RS12230	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUT10_RS12235	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HUT10_RS12240	COG0291	Belongs to the bacterial ribosomal protein bL35 family
HUT10_RS12265	COG2515	1-aminocyclopropane-1-carboxylate deaminase
HUT10_RS12270	COG0251	oxidation-reduction process
HUT10_RS12290	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
HUT10_RS12295	COG2610	gluconate transmembrane transporter activity
HUT10_RS12300	COG2706	6-phosphogluconolactonase activity
HUT10_RS12310	COG1175	transmembrane transport
HUT10_RS12315	COG0395	ABC-type sugar transport system, permease component
HUT10_RS12340	COG4565	transcriptional regulatory protein
HUT10_RS12345	COG3290	protein histidine kinase activity
HUT10_RS12350	COG1301	dicarboxylic acid transport
HUT10_RS12355	COG1733	regulation of RNA biosynthetic process
HUT10_RS12400	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUT10_RS12430	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUT10_RS12435	COG0328	RNA-DNA hybrid ribonuclease activity
HUT10_RS12440	COG3012	SEC-C Motif Domain Protein
HUT10_RS12460	COG2272	Belongs to the type-B carboxylesterase lipase family
HUT10_RS12470	COG0406	alpha-ribazole phosphatase activity
HUT10_RS12490	COG1609	Transcriptional regulator
HUT10_RS12510	COG0823	Involved in the tonB-independent uptake of proteins
HUT10_RS12510	COG1506	peptidase
HUT10_RS12510	COG4946	Tricorn protease homolog
HUT10_RS12520	COG1131	(ABC) transporter
HUT10_RS12530	COG1024	Enoyl-CoA hydratase
HUT10_RS12575	COG0237	dephospho-CoA kinase activity
HUT10_RS12575	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HUT10_RS12815	COG0539	negative regulation of cytoplasmic translation
HUT10_RS12820	COG2226	methyltransferase
HUT10_RS12840	COG1511	domain protein
HUT10_RS12855	COG4221	oxidoreductase activity
HUT10_RS12855	COG3321	synthase
HUT10_RS12855	COG0604	alcohol dehydrogenase
HUT10_RS12855	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT10_RS13010	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS13025	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUT10_RS13025	COG1017	nitric oxide dioxygenase activity
HUT10_RS13035	COG3903	Transcriptional regulator
HUT10_RS13035	COG3629	intracellular signal transduction
HUT10_RS13060	COG4977	sequence-specific DNA binding
HUT10_RS13085	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUT10_RS13105	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT10_RS13115	COG0667	Aldo Keto reductase
HUT10_RS13120	COG0583	DNA-binding transcription factor activity
HUT10_RS13155	COG1733	regulation of RNA biosynthetic process
HUT10_RS13165	COG1309	transcriptional regulator
HUT10_RS13185	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUT10_RS13190	COG1472	Belongs to the glycosyl hydrolase 3 family
HUT10_RS13200	COG1404	Belongs to the peptidase S8 family
HUT10_RS13220	COG1404	Belongs to the peptidase S8 family
HUT10_RS13260	COG4585	Histidine kinase
HUT10_RS13265	COG2197	response regulator
HUT10_RS13290	COG1215	transferase activity, transferring glycosyl groups
HUT10_RS13295	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUT10_RS13300	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HUT10_RS13305	COG2909	trisaccharide binding
HUT10_RS13325	COG0569	domain protein
HUT10_RS13325	COG0475	glutathione-regulated potassium exporter activity
HUT10_RS13355	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HUT10_RS13400	COG3251	PFAM MbtH domain protein
HUT10_RS13465	COG2814	Major facilitator Superfamily
HUT10_RS13495	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HUT10_RS13500	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HUT10_RS13505	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HUT10_RS13515	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HUT10_RS13520	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HUT10_RS13535	COG0768	penicillin binding
HUT10_RS13545	COG0275	rRNA processing
HUT10_RS13550	COG2001	Belongs to the MraZ family
HUT10_RS13575	COG0714	Associated with various cellular activities
HUT10_RS13585	COG1305	Transglutaminase-like
HUT10_RS13595	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HUT10_RS13605	COG1192	Involved in chromosome partitioning
HUT10_RS13610	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HUT10_RS13615	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HUT10_RS13625	COG0167	dihydroorotate dehydrogenase activity
HUT10_RS13630	COG0154	amidase activity
HUT10_RS13645	COG1396	sequence-specific DNA binding
HUT10_RS13660	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HUT10_RS13665	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HUT10_RS13685	COG1674	ftsk spoiiie
HUT10_RS13715	COG1113	amino acid transport
HUT10_RS13735	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HUT10_RS13740	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUT10_RS13745	COG0515	serine threonine protein kinase
HUT10_RS13830	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
HUT10_RS13840	COG1185	polyribonucleotide nucleotidyltransferase activity
HUT10_RS13845	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HUT10_RS13865	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HUT10_RS13895	COG2268	Band 7 protein
HUT10_RS13910	COG4106	trans-aconitate 2-methyltransferase activity
HUT10_RS13930	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HUT10_RS13950	COG0195	Participates in both transcription termination and antitermination
HUT10_RS13955	COG0779	Required for maturation of 30S ribosomal subunits
HUT10_RS13990	COG3226	Transcriptional regulator
HUT10_RS14005	COG2197	response regulator
HUT10_RS14015	COG1733	regulation of RNA biosynthetic process
HUT10_RS14025	COG1309	transcriptional regulator
HUT10_RS14030	COG2936	dipeptidyl-peptidase activity
HUT10_RS14050	COG5002	protein histidine kinase activity
HUT10_RS14055	COG0583	DNA-binding transcription factor activity
HUT10_RS14065	COG1024	Enoyl-CoA hydratase
HUT10_RS14075	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUT10_RS14080	COG1960	acyl-CoA dehydrogenase activity
HUT10_RS14085	COG1316	TRANSCRIPTIONal
HUT10_RS14115	COG0583	DNA-binding transcription factor activity
HUT10_RS14150	COG0583	DNA-binding transcription factor activity
HUT10_RS14155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_RS14240	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HUT10_RS14280	COG1595	DNA-templated transcription, initiation
HUT10_RS14305	COG3507	Belongs to the glycosyl hydrolase 43 family
HUT10_RS14350	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS14385	COG4106	trans-aconitate 2-methyltransferase activity
HUT10_RS14400	COG1595	DNA-templated transcription, initiation
HUT10_RS14435	COG2318	DinB family
HUT10_RS14450	COG0232	Belongs to the dGTPase family. Type 2 subfamily
HUT10_RS14460	COG2197	response regulator
HUT10_RS14465	COG4585	Histidine kinase
HUT10_RS14475	COG1131	(ABC) transporter
HUT10_RS14480	COG0423	glycine-tRNA ligase activity
HUT10_RS14515	COG0701	Predicted permease
HUT10_RS14525	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HUT10_RS14530	COG1381	Involved in DNA repair and RecF pathway recombination
HUT10_RS14560	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HUT10_RS14575	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HUT10_RS14585	COG0537	adenosine 5'-monophosphoramidase activity
HUT10_RS14595	COG0484	heat shock protein binding
HUT10_RS14600	COG1420	regulation of RNA biosynthetic process
HUT10_RS14625	COG0667	Aldo Keto reductase
HUT10_RS14665	COG2205	protein histidine kinase activity
HUT10_RS14670	COG0745	RESPONSE REGULATOR receiver
HUT10_RS14675	COG1953	Uracil, thiamine, allantoin
HUT10_RS14685	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HUT10_RS14725	COG0515	serine threonine protein kinase
HUT10_RS14725	COG2815	serine threonine protein kinase
HUT10_RS14735	COG0542	response to heat
HUT10_RS14745	COG1131	(ABC) transporter
HUT10_RS14745	COG0842	Transport permease protein
HUT10_RS14745	COG1716	ATPase activity
HUT10_RS14800	COG0175	sulfate reduction
HUT10_RS14830	COG1024	Enoyl-CoA hydratase
HUT10_RS14835	COG2732	(Barnase) inhibitor
HUT10_RS14840	COG4290	ribonuclease
HUT10_RS14850	COG0604	alcohol dehydrogenase
HUT10_RS14860	COG0531	amino acid
HUT10_RS14865	COG2070	2-Nitropropane dioxygenase
HUT10_RS14915	COG2226	methyltransferase
HUT10_RS14930	COG0268	Binds directly to 16S ribosomal RNA
HUT10_RS14945	COG2333	competence protein COMEC
HUT10_RS14945	COG0658	competence protein
HUT10_RS14955	COG1307	EDD domain protein, DegV family
HUT10_RS14965	COG0406	alpha-ribazole phosphatase activity
HUT10_RS14970	COG0799	negative regulation of ribosome biogenesis
HUT10_RS14975	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HUT10_RS14985	COG0477	Major facilitator Superfamily
HUT10_RS14990	COG0018	arginyl-trna synthetase
HUT10_RS15005	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS15015	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HUT10_RS15020	COG0211	Belongs to the bacterial ribosomal protein bL27 family
HUT10_RS15025	COG0261	This protein binds to 23S rRNA in the presence of protein L20
HUT10_RS15030	COG1530	ribonuclease E activity
HUT10_RS15030	COG1530	ribonuclease E activity
HUT10_RS15050	COG1131	(ABC) transporter
HUT10_RS15065	COG0105	UTP biosynthetic process
HUT10_RS15115	COG2366	antibiotic biosynthetic process
HUT10_RS15130	COG0285	dihydrofolate synthase activity
HUT10_RS15145	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUT10_RS15145	COG0596	Alpha beta hydrolase
HUT10_RS15155	COG0583	DNA-binding transcription factor activity
HUT10_RS15165	COG0525	valine-tRNA ligase activity
HUT10_RS15185	COG0477	Major facilitator Superfamily
HUT10_RS15200	COG1316	TRANSCRIPTIONal
HUT10_RS15215	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HUT10_RS15245	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HUT10_RS15250	COG0740	serine-type endopeptidase activity
HUT10_RS15255	COG0740	serine-type endopeptidase activity
HUT10_RS15260	COG0544	peptidyl-prolyl cis-trans isomerase activity
HUT10_RS15270	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUT10_RS15280	COG2205	protein histidine kinase activity
HUT10_RS15285	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HUT10_RS15350	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HUT10_RS15390	COG3537	Alpha-1,2-mannosidase
HUT10_RS15405	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HUT10_RS15410	COG3559	Exporter of polyketide antibiotics
HUT10_RS15415	COG1131	(ABC) transporter
HUT10_RS15420	COG1309	transcriptional regulator
HUT10_RS15430	COG1846	Transcriptional regulator
HUT10_RS15430	COG1940	carbohydrate kinase activity
HUT10_RS15470	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HUT10_RS15485	COG2814	Major facilitator Superfamily
HUT10_RS15490	COG0656	L-ascorbic acid biosynthetic process
HUT10_RS15520	COG0693	protein deglycase activity
HUT10_RS15525	COG2208	phosphoserine phosphatase activity
HUT10_RS15530	COG0784	Response regulator, receiver
HUT10_RS15530	COG5002	protein histidine kinase activity
HUT10_RS15555	COG1733	regulation of RNA biosynthetic process
HUT10_RS15560	COG3345	alpha-galactosidase
HUT10_RS15585	COG3321	synthase
HUT10_RS15585	COG0604	alcohol dehydrogenase
HUT10_RS15685	COG2124	cytochrome p450
HUT10_RS15710	COG1819	glycosyl
HUT10_RS15715	COG1131	(ABC) transporter
HUT10_RS15725	COG2197	response regulator
HUT10_RS15730	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HUT10_RS15780	COG0698	ribose 5-phosphate isomerase
HUT10_RS15795	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
HUT10_RS15805	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HUT10_RS15820	COG0668	transmembrane transport
HUT10_RS15830	COG0366	Alpha amylase catalytic
HUT10_RS15845	COG0824	Thioesterase
HUT10_RS15850	COG2902	Dehydrogenase
HUT10_RS15865	COG3336	cytochrome c oxidase
HUT10_RS15880	COG0738	Major facilitator superfamily
HUT10_RS15885	COG1609	Transcriptional regulator
HUT10_RS15910	COG1819	glycosyl
HUT10_RS15925	COG0477	Major facilitator Superfamily
HUT10_RS15930	COG1960	acyl-CoA dehydrogenase activity
HUT10_RS15935	COG0596	Alpha beta hydrolase
HUT10_RS15950	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUT10_RS16005	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT10_RS16010	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT10_RS16045	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HUT10_RS16075	COG0475	glutathione-regulated potassium exporter activity
HUT10_RS16120	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUT10_RS16195	COG1917	Cupin 2, conserved barrel domain protein
HUT10_RS16195	COG4977	sequence-specific DNA binding
HUT10_RS16200	COG3629	intracellular signal transduction
HUT10_RS16205	COG1733	regulation of RNA biosynthetic process
HUT10_RS16210	COG4941	Belongs to the sigma-70 factor family
HUT10_RS16215	COG3795	YCII-related domain
HUT10_RS16225	COG0009	L-threonylcarbamoyladenylate synthase
HUT10_RS16235	COG2197	response regulator
HUT10_RS16245	COG1917	Cupin 2, conserved barrel domain protein
HUT10_RS16245	COG4977	sequence-specific DNA binding
HUT10_RS16250	COG2197	response regulator
HUT10_RS16255	COG4585	Histidine kinase
HUT10_RS16300	COG1937	Protein conserved in bacteria
HUT10_RS16340	COG0477	Major facilitator Superfamily
HUT10_RS16345	COG0587	DNA-directed DNA polymerase activity
HUT10_RS16355	COG1113	amino acid transport
HUT10_RS16405	COG1104	cysteine desulfurase activity
HUT10_RS16415	COG1960	acyl-CoA dehydrogenase activity
HUT10_RS16445	COG0477	Major facilitator Superfamily
HUT10_RS16470	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
HUT10_RS16480	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS16490	COG1620	l-lactate permease
HUT10_RS16495	COG3201	nicotinamide mononucleotide transporter
HUT10_RS16510	COG1668	transmembrane transport
HUT10_RS16515	COG4152	abc transporter atp-binding protein
HUT10_RS16530	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUT10_RS16560	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HUT10_RS16580	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HUT10_RS16585	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HUT10_RS16595	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUT10_RS16595	COG1017	nitric oxide dioxygenase activity
HUT10_RS16635	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HUT10_RS16660	COG0442	prolyl-tRNA aminoacylation
HUT10_RS16695	COG3022	response to hydroperoxide
HUT10_RS16700	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUT10_RS16710	COG1309	transcriptional regulator
HUT10_RS16715	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HUT10_RS16720	COG0583	DNA-binding transcription factor activity
HUT10_RS16760	COG0513	Belongs to the DEAD box helicase family
HUT10_RS16805	COG2186	Transcriptional regulator
HUT10_RS16840	COG0456	acetyltransferase
HUT10_RS16840	COG0454	-acetyltransferase
HUT10_RS16860	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HUT10_RS16865	COG0750	zinc metalloprotease
HUT10_RS16870	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HUT10_RS16880	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HUT10_RS16910	COG2814	Major facilitator Superfamily
HUT10_RS16930	COG3629	intracellular signal transduction
HUT10_RS16930	COG3903	Transcriptional regulator
HUT10_RS16950	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS16955	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HUT10_RS16965	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HUT10_RS16985	COG4941	Belongs to the sigma-70 factor family
HUT10_RS16990	COG3795	YCII-related domain
HUT10_RS17025	COG0789	Transcriptional regulator
HUT10_RS17075	COG0443	Heat shock 70 kDa protein
HUT10_RS17080	COG4245	von Willebrand factor, type A
HUT10_RS17120	COG1674	ftsk spoiiie
HUT10_RS17165	COG0402	S-adenosylhomocysteine deaminase activity
HUT10_RS17175	COG0402	S-adenosylhomocysteine deaminase activity
HUT10_RS17215	COG0820	rRNA (adenine-C2-)-methyltransferase activity
HUT10_RS17225	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HUT10_RS17235	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HUT10_RS17245	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT10_RS17250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HUT10_RS17255	COG1695	Transcriptional regulator
HUT10_RS17275	COG0233	cytoplasmic translational termination
HUT10_RS17280	COG0528	UMP kinase activity
HUT10_RS17285	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HUT10_RS17290	COG0052	Belongs to the universal ribosomal protein uS2 family
HUT10_RS17300	COG1191	sigma factor activity
HUT10_RS17325	COG0792	nuclease activity
HUT10_RS17335	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HUT10_RS17340	COG0681	Belongs to the peptidase S26 family
HUT10_RS17345	COG0335	large ribosomal subunit rRNA binding
HUT10_RS17350	COG0336	Belongs to the RNA methyltransferase TrmD family
HUT10_RS17355	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HUT10_RS17365	COG0228	four-way junction DNA binding
HUT10_RS17390	COG1132	(ABC) transporter
HUT10_RS17400	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HUT10_RS17410	COG1309	transcriptional regulator
HUT10_RS17415	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS17420	COG3706	GGDEF domain
HUT10_RS17425	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
HUT10_RS17450	COG1595	DNA-templated transcription, initiation
HUT10_RS17455	COG0583	DNA-binding transcription factor activity
HUT10_RS17470	COG2873	o-acetylhomoserine
HUT10_RS17475	COG1832	CoA-binding protein
HUT10_RS17495	COG1595	DNA-templated transcription, initiation
HUT10_RS17505	COG4266	Belongs to the allantoicase family
HUT10_RS17510	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HUT10_RS17535	COG1309	transcriptional regulator
HUT10_RS17540	COG3345	alpha-galactosidase
HUT10_RS17545	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HUT10_RS17565	COG3835	regulator
HUT10_RS17575	COG1301	dicarboxylic acid transport
HUT10_RS17605	COG1414	Transcriptional regulator
HUT10_RS17630	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
HUT10_RS17635	COG4146	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUT10_RS17655	COG1254	Belongs to the acylphosphatase family
HUT10_RS17680	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
HUT10_RS17685	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HUT10_RS17690	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HUT10_RS17700	COG0367	asparagine synthase
HUT10_RS17710	COG0673	inositol 2-dehydrogenase activity
HUT10_RS17715	COG1609	Transcriptional regulator
HUT10_RS17720	COG1082	Xylose isomerase domain protein TIM barrel
HUT10_RS17740	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUT10_RS17745	COG3718	enzyme involved in inositol metabolism
HUT10_RS17750	COG3962	Belongs to the TPP enzyme family
HUT10_RS17775	COG0667	Aldo Keto reductase
HUT10_RS17785	COG3706	GGDEF domain
HUT10_RS17830	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HUT10_RS17835	COG0746	molybdenum cofactor guanylyltransferase activity
HUT10_RS17840	COG1414	Transcriptional regulator
HUT10_RS17850	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HUT10_RS17855	COG3485	protocatechuate 3,4-dioxygenase
HUT10_RS17860	COG3485	protocatechuate 3,4-dioxygenase
HUT10_RS17865	COG0183	Belongs to the thiolase family
HUT10_RS17870	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HUT10_RS17875	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HUT10_RS17885	COG0395	ABC-type sugar transport system, permease component
HUT10_RS17895	COG2182	Extracellular solute-binding protein
HUT10_RS17915	COG1929	Belongs to the glycerate kinase type-1 family
HUT10_RS17935	COG2149	membrane
HUT10_RS17960	COG2186	Transcriptional regulator
HUT10_RS17965	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUT10_RS17970	COG1129	ABC transporter
HUT10_RS17980	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS17985	COG4948	Mandelate Racemase Muconate Lactonizing
HUT10_RS17990	COG0179	Fumarylacetoacetate (FAA) hydrolase
HUT10_RS17995	COG2814	Major facilitator Superfamily
HUT10_RS18005	COG0789	Transcriptional regulator
HUT10_RS18035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUT10_RS18040	COG4122	O-methyltransferase activity
HUT10_RS18045	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HUT10_RS18050	COG2186	Transcriptional regulator
HUT10_RS18060	COG1760	l-serine dehydratase
HUT10_RS18065	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HUT10_RS18070	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HUT10_RS18075	COG0509	glycine decarboxylation via glycine cleavage system
HUT10_RS18080	COG0404	The glycine cleavage system catalyzes the degradation of glycine
HUT10_RS18085	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HUT10_RS18085	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HUT10_RS18110	COG1012	belongs to the aldehyde dehydrogenase family
HUT10_RS18115	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HUT10_RS18145	COG3386	PFAM SMP-30 Gluconolaconase
HUT10_RS18165	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HUT10_RS18175	COG0571	ribonuclease III activity
HUT10_RS18180	COG0333	Belongs to the bacterial ribosomal protein bL32 family
HUT10_RS18210	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HUT10_RS18215	COG0742	ribosomal rna small subunit methyltransferase
HUT10_RS18220	COG3973	AAA domain
HUT10_RS18225	COG4249	Peptidase C14 caspase catalytic subunit p20
HUT10_RS18225	COG2319	Wd-40 repeat
HUT10_RS18230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_RS18240	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HUT10_RS18265	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HUT10_RS18345	COG1404	Belongs to the peptidase S8 family
HUT10_RS18375	COG1461	Dihydroxyacetone kinase
HUT10_RS18380	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HUT10_RS18390	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HUT10_RS18395	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HUT10_RS18435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUT10_RS18445	COG2205	protein histidine kinase activity
HUT10_RS18450	COG0745	RESPONSE REGULATOR receiver
HUT10_RS18490	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
HUT10_RS18500	COG1920	GTP binding
HUT10_RS18515	COG3903	Transcriptional regulator
HUT10_RS18515	COG3629	intracellular signal transduction
HUT10_RS18525	COG0066	3-isopropylmalate dehydratase activity
HUT10_RS18530	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HUT10_RS18570	COG0419	ATPase involved in DNA repair
HUT10_RS18575	COG0420	3'-5' exonuclease activity
HUT10_RS18585	COG0776	regulation of translation
HUT10_RS18675	COG0179	Fumarylacetoacetate (FAA) hydrolase
HUT10_RS18680	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HUT10_RS18685	COG0473	3-isopropylmalate dehydrogenase activity
HUT10_RS18690	COG1404	Belongs to the peptidase S8 family
HUT10_RS18730	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HUT10_RS18735	COG0440	acetolactate synthase activity
HUT10_RS18750	COG0129	dihydroxy-acid dehydratase activity
HUT10_RS18770	COG0673	inositol 2-dehydrogenase activity
HUT10_RS18785	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HUT10_RS18790	COG0154	amidase activity
HUT10_RS18795	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HUT10_RS18810	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HUT10_RS18830	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUT10_RS18850	COG0482	sulfurtransferase activity
HUT10_RS18865	COG2197	response regulator
HUT10_RS18870	COG0604	alcohol dehydrogenase
HUT10_RS18885	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
HUT10_RS18895	COG1307	EDD domain protein, DegV family
HUT10_RS18905	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HUT10_RS18915	COG0386	Belongs to the glutathione peroxidase family
HUT10_RS18930	COG2226	methyltransferase
HUT10_RS18995	COG0110	maltose O-acetyltransferase activity
HUT10_RS19005	COG0791	NLP P60 protein
HUT10_RS19005	COG3883	PFAM NLP P60 protein
HUT10_RS19015	COG1733	regulation of RNA biosynthetic process
HUT10_RS19020	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT10_RS19060	COG2188	Transcriptional regulator
HUT10_RS19070	COG3979	chitinase
HUT10_RS19095	COG2226	methyltransferase
HUT10_RS19100	COG1024	Enoyl-CoA hydratase
HUT10_RS19105	COG1119	ATPase activity
HUT10_RS19145	COG0058	SHG alpha-glucan phosphorylase activity
HUT10_RS19170	COG1846	Transcriptional regulator
HUT10_RS19180	COG3537	Alpha-1,2-mannosidase
HUT10_RS19185	COG3537	Alpha-1,2-mannosidase
HUT10_RS19190	COG1609	Transcriptional regulator
HUT10_RS19210	COG1879	ABC-type sugar transport system periplasmic component
HUT10_RS19220	COG3275	phosphorelay sensor kinase activity
HUT10_RS19225	COG3279	Response regulator of the LytR AlgR family
HUT10_RS19235	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUT10_RS19245	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUT10_RS19250	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HUT10_RS19255	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HUT10_RS19260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUT10_RS19275	COG0183	Belongs to the thiolase family
HUT10_RS19280	COG0346	lactoylglutathione lyase activity
HUT10_RS19295	COG0604	alcohol dehydrogenase
HUT10_RS19310	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
HUT10_RS19320	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUT10_RS19325	COG2151	metal-sulfur cluster biosynthetic enzyme
HUT10_RS19330	COG3396	Phenylacetate-CoA oxygenase
HUT10_RS19335	COG3460	Phenylacetate-CoA oxygenase
HUT10_RS19340	COG3396	Phenylacetate-CoA oxygenase
HUT10_RS19345	COG1012	belongs to the aldehyde dehydrogenase family
HUT10_RS19345	COG2030	dehydratase
HUT10_RS19360	COG1309	transcriptional regulator
HUT10_RS19385	COG2072	flavoprotein involved in K transport
HUT10_RS19400	COG2183	response to ionizing radiation
HUT10_RS19420	COG0513	Belongs to the DEAD box helicase family
HUT10_RS19425	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUT10_RS19450	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HUT10_RS19475	COG1940	carbohydrate kinase activity
HUT10_RS19480	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
HUT10_RS19480	COG3408	Glycogen debranching enzyme
HUT10_RS19490	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
HUT10_RS19505	COG3540	Alkaline phosphatase
HUT10_RS19515	COG3903	Transcriptional regulator
HUT10_RS19515	COG3629	intracellular signal transduction
HUT10_RS19520	COG4991	sh3 domain protein
HUT10_RS19535	COG1879	ABC-type sugar transport system periplasmic component
HUT10_RS19550	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUT10_RS19555	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUT10_RS19555	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUT10_RS19575	COG1129	ABC transporter
HUT10_RS19580	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUT10_RS19585	COG2186	Transcriptional regulator
HUT10_RS19615	COG1131	(ABC) transporter
HUT10_RS19635	COG2964	Protein conserved in bacteria
HUT10_RS19640	COG1126	abc transporter atp-binding protein
HUT10_RS19645	COG0765	amino acid transport
HUT10_RS19650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUT10_RS19685	COG1733	regulation of RNA biosynthetic process
HUT10_RS19735	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HUT10_RS19775	COG2272	Belongs to the type-B carboxylesterase lipase family
HUT10_RS19790	COG1234	tRNA 3'-trailer cleavage
HUT10_RS19835	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
HUT10_RS19910	COG0330	HflC and HflK could
HUT10_RS19985	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS19990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUT10_RS19995	COG1012	belongs to the aldehyde dehydrogenase family
HUT10_RS20015	COG0179	Fumarylacetoacetate (FAA) hydrolase
HUT10_RS20035	COG3848	Pyruvate phosphate dikinase
HUT10_RS20035	COG0574	Belongs to the PEP-utilizing enzyme family
HUT10_RS20040	COG1802	Transcriptional regulator
HUT10_RS20045	COG0574	Belongs to the PEP-utilizing enzyme family
HUT10_RS20045	COG3848	Pyruvate phosphate dikinase
HUT10_RS20050	COG0656	L-ascorbic acid biosynthetic process
HUT10_RS20055	COG0667	Aldo Keto reductase
HUT10_RS20060	COG2814	Major facilitator Superfamily
HUT10_RS20065	COG1309	transcriptional regulator
HUT10_RS20100	COG2080	2 iron, 2 sulfur cluster binding
HUT10_RS20105	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HUT10_RS20110	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HUT10_RS20140	COG0789	Transcriptional regulator
HUT10_RS20145	COG4221	oxidoreductase activity
HUT10_RS20160	COG2197	response regulator
HUT10_RS20170	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_RS20215	COG0477	Major facilitator Superfamily
HUT10_RS20230	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_RS20235	COG0156	8-amino-7-oxononanoate synthase activity
HUT10_RS20240	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_RS20250	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HUT10_RS20260	COG2197	response regulator
HUT10_RS20285	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_RS20340	COG1131	(ABC) transporter
HUT10_RS20370	COG1136	(ABC) transporter
HUT10_RS20400	COG1309	transcriptional regulator
HUT10_RS20410	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUT10_RS20430	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HUT10_RS20445	COG3903	Transcriptional regulator
HUT10_RS20445	COG3629	intracellular signal transduction
HUT10_RS20480	COG1846	Transcriptional regulator
HUT10_RS20485	COG0697	spore germination
HUT10_RS20575	COG0596	Alpha beta hydrolase
HUT10_RS20595	COG0596	Alpha beta hydrolase
HUT10_RS20605	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HUT10_RS20615	COG1053	succinate dehydrogenase
HUT10_RS20625	COG1486	melibiose metabolic process
HUT10_RS20630	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUT10_RS20655	COG1309	transcriptional regulator
HUT10_RS20665	COG0596	Alpha beta hydrolase
HUT10_RS20675	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS20690	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS20700	COG2813	Specifically methylates the guanine in position
HUT10_RS20750	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HUT10_RS20775	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS20785	COG5640	endopeptidase activity
HUT10_RS20790	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HUT10_RS20795	COG1609	Transcriptional regulator
HUT10_RS20800	COG1879	ABC-type sugar transport system periplasmic component
HUT10_RS20805	COG1129	ABC transporter
HUT10_RS20810	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUT10_RS20815	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUT10_RS20855	COG0187	DNA topoisomerase II activity
HUT10_RS20860	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HUT10_RS20890	COG3883	PFAM NLP P60 protein
HUT10_RS20890	COG0791	NLP P60 protein
HUT10_RS20910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUT10_RS20915	COG1643	Atp-dependent helicase
HUT10_RS20920	COG1131	(ABC) transporter
HUT10_RS20940	COG2197	response regulator
HUT10_RS20945	COG4585	Histidine kinase
HUT10_RS20975	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HUT10_RS20980	COG1228	amidohydrolase
HUT10_RS20995	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HUT10_RS21000	COG2986	histidine ammonia-lyase
HUT10_RS21025	COG3706	GGDEF domain
HUT10_RS21045	COG4585	Histidine kinase
HUT10_RS21050	COG2197	response regulator
HUT10_RS21070	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HUT10_RS21075	COG2177	Part of the ABC transporter FtsEX involved in
HUT10_RS21080	COG2884	Cell division ATP-binding protein ftsE
HUT10_RS21085	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HUT10_RS21115	COG1615	UPF0182 protein
HUT10_RS21145	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HUT10_RS21185	COG0174	glutamine synthetase
HUT10_RS21195	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
HUT10_RS21205	COG0519	Catalyzes the synthesis of GMP from XMP
HUT10_RS21205	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HUT10_RS21215	COG1522	sequence-specific DNA binding
HUT10_RS21235	COG0154	amidase activity
HUT10_RS21240	COG0174	glutamine synthetase
HUT10_RS21260	COG0653	protein targeting
HUT10_RS21265	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HUT10_RS21265	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HUT10_RS21275	COG1404	Belongs to the peptidase S8 family
HUT10_RS21285	COG2318	DinB family
HUT10_RS21300	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
HUT10_RS21310	COG1968	undecaprenyl-diphosphatase activity
HUT10_RS21315	COG0596	Alpha beta hydrolase
HUT10_RS21320	COG1309	transcriptional regulator
HUT10_RS21325	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS21330	COG1177	transmembrane transport
HUT10_RS21335	COG1176	ABC-type spermidine putrescine transport system, permease component I
HUT10_RS21340	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
HUT10_RS21345	COG3842	ATPase activity
HUT10_RS21350	COG1012	belongs to the aldehyde dehydrogenase family
HUT10_RS21390	COG1012	belongs to the aldehyde dehydrogenase family
HUT10_RS21400	COG4585	Histidine kinase
HUT10_RS21520	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HUT10_RS21550	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HUT10_RS21560	COG3265	gluconokinase activity
HUT10_RS21575	COG0640	Transcriptional regulator
HUT10_RS21590	COG1486	melibiose metabolic process
HUT10_RS21595	COG0395	ABC-type sugar transport system, permease component
HUT10_RS21600	COG1175	transmembrane transport
HUT10_RS21610	COG1940	carbohydrate kinase activity
HUT10_RS21620	COG0612	Peptidase, M16
HUT10_RS21640	COG2321	neutral zinc metallopeptidase
HUT10_RS21660	COG0714	Associated with various cellular activities
HUT10_RS21730	COG2378	regulation of single-species biofilm formation
HUT10_RS21755	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HUT10_RS21755	COG2146	nitrite reductase [NAD(P)H] activity
HUT10_RS21760	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HUT10_RS21760	COG2146	nitrite reductase [NAD(P)H] activity
HUT10_RS21770	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HUT10_RS21775	COG0243	molybdopterin cofactor binding
HUT10_RS21800	COG1309	transcriptional regulator
HUT10_RS21805	COG2267	carboxylic ester hydrolase activity
HUT10_RS21825	COG3415	Transposase
HUT10_RS21825	COG2801	Transposase and inactivated derivatives
HUT10_RS21845	COG0513	Belongs to the DEAD box helicase family
HUT10_RS21870	COG2095	MarC family integral membrane protein
HUT10_RS21875	COG0613	PHP domain protein
HUT10_RS21905	COG0598	Magnesium transport protein CorA
HUT10_RS21945	COG4585	Histidine kinase
HUT10_RS21950	COG2197	response regulator
HUT10_RS21960	COG1309	transcriptional regulator
HUT10_RS22015	COG0330	HflC and HflK could
HUT10_RS22025	COG2239	Acts as a magnesium transporter
HUT10_RS22040	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HUT10_RS22045	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUT10_RS22055	COG1595	DNA-templated transcription, initiation
HUT10_RS22060	COG4122	O-methyltransferase activity
HUT10_RS22065	COG2814	Major facilitator Superfamily
HUT10_RS22075	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HUT10_RS22085	COG1024	Enoyl-CoA hydratase
HUT10_RS22090	COG2818	Glycosylase
HUT10_RS22115	COG1271	oxidase subunit
HUT10_RS22120	COG1294	oxidase, subunit
HUT10_RS22125	COG4988	ABC transporter
HUT10_RS22130	COG1132	(ABC) transporter
HUT10_RS22135	COG0463	Glycosyl transferase, family 2
HUT10_RS22150	COG1611	Belongs to the LOG family
HUT10_RS22155	COG1073	alpha beta
HUT10_RS22160	COG1510	regulation of RNA biosynthetic process
HUT10_RS22165	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HUT10_RS22265	COG0391	Required for morphogenesis under gluconeogenic growth conditions
HUT10_RS22270	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
HUT10_RS22270	COG0778	Nitroreductase
HUT10_RS22285	COG1725	Transcriptional regulator
HUT10_RS22320	COG0438	transferase activity, transferring glycosyl groups
HUT10_RS22345	COG1309	transcriptional regulator
HUT10_RS22360	COG1316	TRANSCRIPTIONal
HUT10_RS22365	COG1316	TRANSCRIPTIONal
HUT10_RS22405	COG1073	alpha beta
HUT10_RS22420	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_RS22480	COG2197	response regulator
HUT10_RS22485	COG2197	response regulator
HUT10_RS22490	COG2205	protein histidine kinase activity
HUT10_RS22500	COG0483	inositol monophosphate 1-phosphatase activity
HUT10_RS22530	COG3103	Sh3 type 3 domain protein
HUT10_RS22530	COG1388	LysM domain
HUT10_RS22530	COG0791	NLP P60 protein
HUT10_RS22545	COG2197	response regulator
HUT10_RS22550	COG4585	Histidine kinase
HUT10_RS22575	COG1595	DNA-templated transcription, initiation
HUT10_RS22600	COG0583	DNA-binding transcription factor activity
HUT10_RS22620	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS22630	COG1733	regulation of RNA biosynthetic process
HUT10_RS22640	COG1309	transcriptional regulator
HUT10_RS22645	COG0655	NAD(P)H dehydrogenase (quinone) activity
HUT10_RS22660	COG4585	Histidine kinase
HUT10_RS22670	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUT10_RS22680	COG1846	Transcriptional regulator
HUT10_RS22685	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_RS22710	COG0424	maF-like protein
HUT10_RS22715	COG1301	dicarboxylic acid transport
HUT10_RS22730	COG4770	biotin carboxylase activity
HUT10_RS22750	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HUT10_RS22755	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HUT10_RS22760	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HUT10_RS22800	COG1473	amidohydrolase
HUT10_RS22800	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
HUT10_RS22825	COG0515	serine threonine protein kinase
HUT10_RS22855	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HUT10_RS22880	COG0402	S-adenosylhomocysteine deaminase activity
HUT10_RS22895	COG2205	protein histidine kinase activity
HUT10_RS22900	COG0745	RESPONSE REGULATOR receiver
HUT10_RS22905	COG0475	glutathione-regulated potassium exporter activity
HUT10_RS22925	COG0667	Aldo Keto reductase
HUT10_RS22930	COG0789	Transcriptional regulator
HUT10_RS22965	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HUT10_RS22970	COG1012	belongs to the aldehyde dehydrogenase family
HUT10_RS22975	COG1012	belongs to the aldehyde dehydrogenase family
HUT10_RS23020	COG0395	ABC-type sugar transport system, permease component
HUT10_RS23035	COG1063	alcohol dehydrogenase
HUT10_RS23065	COG1733	regulation of RNA biosynthetic process
HUT10_RS23090	COG2271	Major facilitator Superfamily
HUT10_RS23095	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HUT10_RS23135	COG3345	alpha-galactosidase
HUT10_RS23140	COG2009	succinate dehydrogenase
HUT10_RS23155	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HUT10_RS23175	COG1295	ribonuclease BN
HUT10_RS23185	COG0180	Tryptophanyl-tRNA synthetase
HUT10_RS23235	COG2226	methyltransferase
HUT10_RS23265	COG3415	Transposase
HUT10_RS23265	COG2801	Transposase and inactivated derivatives
HUT10_RS23270	COG2814	Major facilitator Superfamily
HUT10_RS23275	COG0640	Transcriptional regulator
HUT10_RS23280	COG2814	Major facilitator Superfamily
HUT10_RS23290	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HUT10_RS23315	COG0587	DNA-directed DNA polymerase activity
HUT10_RS23345	COG0138	bifunctional purine biosynthesis protein purh
HUT10_RS23370	COG0045	succinate-CoA ligase (ADP-forming) activity
HUT10_RS23390	COG2801	Transposase and inactivated derivatives
HUT10_RS23390	COG3415	Transposase
HUT10_RS23425	COG2815	serine threonine protein kinase
HUT10_RS23425	COG0515	serine threonine protein kinase
HUT10_RS23430	COG0515	serine threonine protein kinase
HUT10_RS23430	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HUT10_RS23435	COG0583	DNA-binding transcription factor activity
HUT10_RS23465	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HUT10_RS23465	COG0519	Catalyzes the synthesis of GMP from XMP
HUT10_RS23480	COG1012	belongs to the aldehyde dehydrogenase family
HUT10_RS23485	COG0277	FAD linked oxidase domain protein
HUT10_RS23505	COG0516	GMP reductase activity
HUT10_RS23570	COG0459	protein refolding
HUT10_RS23575	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HUT10_RS23585	COG1215	transferase activity, transferring glycosyl groups
HUT10_RS23605	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HUT10_RS23610	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HUT10_RS23615	COG0456	acetyltransferase
HUT10_RS23625	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_RS23630	COG0825	malonyl-CoA metabolic process
HUT10_RS23630	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HUT10_RS23640	COG0802	atpase or kinase
HUT10_RS23650	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HUT10_RS23655	COG3842	ATPase activity
HUT10_RS23660	COG1070	Carbohydrate kinase
HUT10_RS23665	COG1349	DNA-binding transcription factor activity
HUT10_RS23705	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_RS23715	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HUT10_RS23720	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HUT10_RS23725	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HUT10_RS23755	COG0443	Heat shock 70 kDa protein
HUT10_RS23760	COG1674	ftsk spoiiie
HUT10_RS23770	COG1404	Belongs to the peptidase S8 family
HUT10_RS23805	COG0101	tRNA pseudouridine synthase activity
HUT10_RS23810	COG0203	ribosomal protein L17
HUT10_RS23815	COG0202	RNA polymerase activity
HUT10_RS23820	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HUT10_RS23825	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HUT10_RS23840	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HUT10_RS23845	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HUT10_RS23855	COG0563	adenylate kinase activity
HUT10_RS23865	COG1280	lysine exporter protein (LysE YggA)
HUT10_RS23875	COG0200	Binds to the 23S rRNA
HUT10_RS23880	COG1841	ribosomal large subunit assembly
HUT10_RS23885	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HUT10_RS23890	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HUT10_RS23895	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HUT10_RS23900	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HUT10_RS23910	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HUT10_RS23915	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HUT10_RS23920	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HUT10_RS23925	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HUT10_RS23930	COG0255	Belongs to the universal ribosomal protein uL29 family
HUT10_RS23935	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HUT10_RS23940	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HUT10_RS23945	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HUT10_RS23950	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HUT10_RS23955	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HUT10_RS23960	COG0089	rRNA binding
HUT10_RS23965	COG0088	Forms part of the polypeptide exit tunnel
HUT10_RS23970	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HUT10_RS23975	COG0051	transcription antitermination factor activity, RNA binding
HUT10_RS23985	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HUT10_RS23990	COG0049	tRNA binding
HUT10_RS23995	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HUT10_RS24060	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HUT10_RS24070	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HUT10_RS24085	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
HUT10_RS24095	COG3958	Transketolase
HUT10_RS24100	COG3959	Transketolase, thiamine diphosphate binding domain
HUT10_RS24110	COG2124	cytochrome p450
HUT10_RS24125	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT10_RS24135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_RS24150	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HUT10_RS24170	COG2124	cytochrome p450
HUT10_RS24175	COG2124	cytochrome p450
HUT10_RS24195	COG0477	Major facilitator Superfamily
HUT10_RS24205	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HUT10_RS24215	COG0546	phosphoglycolate phosphatase activity
HUT10_RS24230	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HUT10_RS24235	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
HUT10_RS24300	COG0673	inositol 2-dehydrogenase activity
HUT10_RS24320	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HUT10_RS24345	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HUT10_RS24360	COG0222	ribosome binding
HUT10_RS24380	COG0081	regulation of translation
HUT10_RS24410	COG1725	Transcriptional regulator
HUT10_RS24430	COG2030	dehydratase
HUT10_RS24435	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HUT10_RS24480	COG1666	GTP binding
HUT10_RS24505	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_RS24520	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HUT10_RS24535	COG4310	Domain of unknown function (DUF2172)
HUT10_RS24545	COG1215	transferase activity, transferring glycosyl groups
HUT10_RS24555	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
HUT10_RS24560	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HUT10_RS24605	COG0367	asparagine synthase
HUT10_RS24625	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HUT10_RS24640	COG1834	amidinotransferase
HUT10_RS24645	COG1522	sequence-specific DNA binding
HUT10_RS24665	COG0674	pyruvate-flavodoxin oxidoreductase activity
HUT10_RS24665	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HUT10_RS24670	COG1013	pyruvate-flavodoxin oxidoreductase activity
HUT10_RS24715	COG1007	ATP synthesis coupled electron transport
HUT10_RS24725	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HUT10_RS24730	COG0713	ATP synthesis coupled electron transport
HUT10_RS24735	COG0839	Belongs to the complex I subunit 6 family
HUT10_RS24740	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT10_RS24745	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
HUT10_RS24750	COG1034	ATP synthesis coupled electron transport
HUT10_RS24755	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HUT10_RS24765	COG0649	NAD binding
HUT10_RS24770	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT10_RS24775	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HUT10_RS24790	COG2226	methyltransferase
HUT10_RS24795	COG0438	transferase activity, transferring glycosyl groups
HUT10_RS24820	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HUT10_RS24825	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HUT10_RS24855	COG1522	sequence-specific DNA binding
HUT10_RS24875	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HUT10_RS24885	COG0785	Cytochrome C biogenesis protein
HUT10_RS24900	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HUT10_RS24905	COG0406	alpha-ribazole phosphatase activity
HUT10_RS24910	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HUT10_RS24925	COG1136	(ABC) transporter
HUT10_RS24925	COG0577	efflux transmembrane transporter activity
HUT10_RS24930	COG1136	(ABC) transporter
HUT10_RS24930	COG0577	efflux transmembrane transporter activity
HUT10_RS24935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HUT10_RS24970	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HUT10_RS24970	COG1648	precorrin-2 dehydrogenase activity
HUT10_RS24975	COG0181	hydroxymethylbilane synthase activity
HUT10_RS24980	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HUT10_RS24985	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HUT10_RS25000	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_RS25005	COG1595	DNA-templated transcription, initiation
HUT10_RS25045	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HUT10_RS25075	COG5002	protein histidine kinase activity
HUT10_RS25080	COG0667	Aldo Keto reductase
HUT10_RS25095	COG0588	phosphoglycerate mutase activity
HUT10_RS25110	COG0438	transferase activity, transferring glycosyl groups
HUT10_RS25125	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HUT10_RS25155	COG1064	alcohol dehydrogenase
HUT10_RS25160	COG1309	transcriptional regulator
HUT10_RS25170	COG0640	Transcriptional regulator
HUT10_RS25180	COG2130	NADP-dependent
HUT10_RS25205	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUT10_RS25220	COG1846	Transcriptional regulator
HUT10_RS25235	COG1174	glycine betaine transport
HUT10_RS25255	COG2986	histidine ammonia-lyase
HUT10_RS25285	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HUT10_RS25290	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HUT10_RS25310	COG2733	membrane
HUT10_RS25325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUT10_RS25330	COG2364	Membrane
HUT10_RS25355	COG2515	1-aminocyclopropane-1-carboxylate deaminase
HUT10_RS25445	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HUT10_RS25470	COG1414	Transcriptional regulator
HUT10_RS25485	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HUT10_RS25490	COG2233	PERMEase
HUT10_RS25535	COG2226	methyltransferase
HUT10_RS25590	COG2188	Transcriptional regulator
HUT10_RS25635	COG1278	Cold shock
HUT10_RS25650	COG1595	DNA-templated transcription, initiation
HUT10_RS25670	COG0515	serine threonine protein kinase
HUT10_RS25675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUT10_RS25690	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HUT10_RS25695	COG3199	ATP-NAD kinase
HUT10_RS25700	COG2217	Heavy metal translocating P-type atpase
HUT10_RS25715	COG0028	Belongs to the TPP enzyme family
HUT10_RS25730	COG0515	serine threonine protein kinase
HUT10_RS25780	COG2318	DinB family
HUT10_RS25790	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HUT10_RS25805	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HUT10_RS25820	COG1846	Transcriptional regulator
HUT10_RS25840	COG1902	pentaerythritol trinitrate reductase activity
HUT10_RS25840	COG0446	pyridine nucleotide-disulphide oxidoreductase
HUT10_RS25845	COG0287	Prephenate dehydrogenase
HUT10_RS25900	COG1131	(ABC) transporter
HUT10_RS25905	COG3559	Exporter of polyketide antibiotics
HUT10_RS25970	COG0667	Aldo Keto reductase
HUT10_RS25980	COG3583	domain protein
HUT10_RS25980	COG3584	3D domain protein
HUT10_RS26010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HUT10_RS26015	COG3469	chitinase activity
HUT10_RS26045	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUT10_RS26055	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HUT10_RS26085	COG2186	Transcriptional regulator
HUT10_RS26090	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HUT10_RS26105	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUT10_RS26110	COG1522	sequence-specific DNA binding
HUT10_RS26125	COG1672	PFAM Archaeal ATPase
HUT10_RS26125	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
HUT10_RS26150	COG1116	anion transmembrane transporter activity
HUT10_RS26155	COG3290	protein histidine kinase activity
HUT10_RS26160	COG4565	transcriptional regulatory protein
HUT10_RS26220	COG2234	aminopeptidase activity
HUT10_RS26225	COG1063	alcohol dehydrogenase
HUT10_RS26250	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
HUT10_RS26260	COG2089	acid synthase
HUT10_RS26275	COG1216	Glycosyl transferase, family 2
HUT10_RS26305	COG1216	Glycosyl transferase, family 2
HUT10_RS26315	COG0277	FAD linked oxidase domain protein
HUT10_RS26320	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS26335	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HUT10_RS26355	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_RS26360	COG0561	phosphatase activity
HUT10_RS26395	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_RS26410	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HUT10_RS26425	COG3293	Transposase
HUT10_RS26445	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HUT10_RS26450	COG0438	transferase activity, transferring glycosyl groups
HUT10_RS26480	COG0579	oxidoreductase
HUT10_RS26490	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HUT10_RS26495	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HUT10_RS26510	COG0596	Alpha beta hydrolase
HUT10_RS26520	COG0754	glutathionylspermidine amidase activity
HUT10_RS26555	COG0406	alpha-ribazole phosphatase activity
HUT10_RS26565	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HUT10_RS26570	COG1072	(Pantothenic acid kinase))
HUT10_RS26585	COG4715	Zinc finger, swim domain protein
HUT10_RS26650	COG4988	ABC transporter
HUT10_RS26655	COG1294	oxidase, subunit
HUT10_RS26660	COG1271	oxidase subunit
HUT10_RS26700	COG2319	Wd-40 repeat
HUT10_RS26700	COG4249	Peptidase C14 caspase catalytic subunit p20
HUT10_RS26775	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HUT10_RS26800	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUT10_RS26825	COG3275	phosphorelay sensor kinase activity
HUT10_RS26830	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HUT10_RS26875	COG1216	Glycosyl transferase, family 2
HUT10_RS26875	COG0438	transferase activity, transferring glycosyl groups
HUT10_RS26900	COG2197	response regulator
HUT10_RS26905	COG4585	Histidine kinase
HUT10_RS26915	COG0477	Major facilitator Superfamily
HUT10_RS26940	COG0405	Gamma-glutamyltransferase
HUT10_RS26950	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HUT10_RS26960	COG2226	methyltransferase
HUT10_RS26985	COG1174	glycine betaine transport
HUT10_RS26995	COG1174	glycine betaine transport
HUT10_RS27010	COG2372	response to copper ion
HUT10_RS27010	COG1276	copper resistance
HUT10_RS27040	COG2211	Major facilitator Superfamily
HUT10_RS27050	COG1309	transcriptional regulator
HUT10_RS27070	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HUT10_RS27075	COG0702	epimerase
HUT10_RS27085	COG2301	Belongs to the HpcH HpaI aldolase family
HUT10_RS27105	COG0154	amidase activity
HUT10_RS27110	COG4608	Belongs to the ABC transporter superfamily
HUT10_RS27115	COG0444	Belongs to the ABC transporter superfamily
HUT10_RS27130	COG0747	negative chemotaxis
HUT10_RS27135	COG2186	Transcriptional regulator
HUT10_RS27165	COG0626	cystathionine gamma-synthase activity
HUT10_RS27195	COG1716	ATPase activity
HUT10_RS27200	COG1716	ATPase activity
HUT10_RS27215	COG0768	penicillin binding
HUT10_RS27220	COG0515	serine threonine protein kinase
HUT10_RS27225	COG2815	serine threonine protein kinase
HUT10_RS27225	COG0515	serine threonine protein kinase
HUT10_RS27255	COG2197	response regulator
HUT10_RS27290	COG3764	Sortase (surface protein transpeptidase)
HUT10_RS27305	COG0705	Rhomboid family
HUT10_RS27305	COG0457	Tetratricopeptide repeat
HUT10_RS27345	COG0321	lipoyl(octanoyl) transferase activity
HUT10_RS27400	COG0640	Transcriptional regulator
HUT10_RS27435	COG0187	DNA topoisomerase II activity
HUT10_RS27440	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
HUT10_RS27445	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HUT10_RS27450	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
HUT10_RS27455	COG0592	DNA-directed DNA polymerase activity
HUT10_RS27470	COG0594	ribonuclease P activity
HUT10_RS27475	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
HUT10_RS27480	COG0706	membrane insertase activity
HUT10_RS27490	COG0357	Ribosomal RNA small subunit methyltransferase G
HUT10_RS27495	COG1192	Involved in chromosome partitioning
HUT10_RS27505	COG1181	Belongs to the D-alanine--D-alanine ligase family
HUT10_RS27520	COG0860	N-Acetylmuramoyl-L-alanine amidase
HUT10_RS27520	COG3409	Peptidoglycan-binding domain 1 protein
HUT10_RS27525	COG3118	belongs to the thioredoxin family
HUT10_RS27525	COG0492	ferredoxin-NADP+ reductase activity
HUT10_RS27540	COG1595	DNA-templated transcription, initiation
HUT10_RS27570	COG0617	tRNA 3'-terminal CCA addition
HUT10_RS27650	COG0495	leucyl-tRNA aminoacylation
HUT10_RS27655	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS27710	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUT10_RS27720	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HUT10_RS27725	COG0477	Major facilitator Superfamily
HUT10_RS27740	COG2197	response regulator
HUT10_RS27765	COG3384	dioxygenase
HUT10_RS27805	COG0359	binds to the 23S rRNA
HUT10_RS27810	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HUT10_RS27820	COG0360	Binds together with S18 to 16S ribosomal RNA
HUT10_RS27850	COG1940	carbohydrate kinase activity
HUT10_RS27855	COG0673	inositol 2-dehydrogenase activity
HUT10_RS27860	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HUT10_RS27865	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HUT10_RS27875	COG1695	Transcriptional regulator
HUT10_RS27885	COG1595	DNA-templated transcription, initiation
HUT10_RS27895	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUT10_RS27900	COG1846	Transcriptional regulator
HUT10_RS27905	COG2814	Major facilitator Superfamily
HUT10_RS27920	COG4221	oxidoreductase activity
HUT10_RS27925	COG0402	S-adenosylhomocysteine deaminase activity
HUT10_RS27930	COG2197	response regulator
HUT10_RS27940	COG1136	(ABC) transporter
HUT10_RS27950	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HUT10_RS27965	COG1131	(ABC) transporter
HUT10_RS27985	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS27990	COG2197	response regulator
HUT10_RS27995	COG4585	Histidine kinase
HUT10_RS28020	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HUT10_RS28035	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
HUT10_RS28050	COG1131	(ABC) transporter
HUT10_RS28120	COG0183	Belongs to the thiolase family
HUT10_RS28125	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS28130	COG2030	dehydratase
HUT10_RS28135	COG1309	transcriptional regulator
HUT10_RS28170	COG3030	protein affecting phage T7 exclusion by the F plasmid
HUT10_RS28195	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUT10_RS28200	COG0022	dehydrogenase e1 component
HUT10_RS28210	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUT10_RS28225	COG1305	Transglutaminase-like
HUT10_RS28270	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HUT10_RS28290	COG0477	Major facilitator Superfamily
HUT10_RS28300	COG1960	acyl-CoA dehydrogenase activity
HUT10_RS28305	COG2197	response regulator
HUT10_RS28310	COG3663	DNA glycosylase
HUT10_RS28350	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUT10_RS28365	COG3795	YCII-related domain
HUT10_RS28370	COG4941	Belongs to the sigma-70 factor family
HUT10_RS28390	COG0546	phosphoglycolate phosphatase activity
HUT10_RS28470	COG2340	Cysteine-rich secretory protein family
HUT10_RS28485	COG2181	nitrate reductase activity
HUT10_RS28485	COG0247	lactate metabolic process
HUT10_RS28530	COG0443	Heat shock 70 kDa protein
HUT10_RS28535	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HUT10_RS28540	COG0484	heat shock protein binding
HUT10_RS28545	COG0789	Transcriptional regulator
HUT10_RS28560	COG0412	Dienelactone hydrolase
HUT10_RS28565	COG1017	nitric oxide dioxygenase activity
HUT10_RS28565	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HUT10_RS28585	COG0542	response to heat
HUT10_RS28600	COG0300	oxidoreductase activity
HUT10_RS28605	COG1136	(ABC) transporter
HUT10_RS28620	COG1595	DNA-templated transcription, initiation
HUT10_RS28650	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUT10_RS28660	COG0243	molybdopterin cofactor binding
HUT10_RS28675	COG1609	Transcriptional regulator
HUT10_RS28700	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUT10_RS28705	COG0572	uridine kinase
HUT10_RS28710	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS28725	COG0586	Pfam SNARE associated Golgi protein
HUT10_RS28735	COG0477	Major facilitator Superfamily
HUT10_RS28745	COG3467	pyridoxamine 5'-phosphate
HUT10_RS28750	COG0277	FAD linked oxidase domain protein
HUT10_RS28755	COG0586	Pfam SNARE associated Golgi protein
HUT10_RS28800	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS28805	COG0667	Aldo Keto reductase
HUT10_RS28860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_RS28890	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HUT10_RS28905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_RS28910	COG0025	NhaP-type Na H and K H
HUT10_RS28915	COG2814	Major facilitator Superfamily
HUT10_RS28930	COG0584	glycerophosphoryl diester phosphodiesterase
HUT10_RS28975	COG0436	Aminotransferase
HUT10_RS29035	COG4948	Mandelate Racemase Muconate Lactonizing
HUT10_RS29040	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HUT10_RS29050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUT10_RS29060	COG0765	amino acid transport
HUT10_RS29065	COG1126	abc transporter atp-binding protein
HUT10_RS29080	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
HUT10_RS29130	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HUT10_RS29135	COG0047	phosphoribosylformylglycinamidine synthase activity
HUT10_RS29145	COG1132	(ABC) transporter
HUT10_RS29155	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HUT10_RS29160	COG2197	response regulator
HUT10_RS29165	COG4585	Histidine kinase
HUT10_RS29230	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
HUT10_RS29265	COG3845	ABC transporter
HUT10_RS29315	COG1984	allophanate hydrolase subunit 2
HUT10_RS29320	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
HUT10_RS29325	COG4044	May play a role in the intracellular transport of hydrophobic ligands
HUT10_RS29355	COG0745	RESPONSE REGULATOR receiver
HUT10_RS29365	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HUT10_RS29380	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HUT10_RS29390	COG1316	TRANSCRIPTIONal
HUT10_RS29395	COG3706	GGDEF domain
HUT10_RS29400	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
HUT10_RS29405	COG0596	Alpha beta hydrolase
HUT10_RS29425	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUT10_RS29430	COG1397	ADP-ribosylglycohydrolase
HUT10_RS29435	COG2188	Transcriptional regulator
HUT10_RS29460	COG0673	inositol 2-dehydrogenase activity
HUT10_RS29495	COG3973	AAA domain
HUT10_RS29505	COG0531	amino acid
HUT10_RS29525	COG1802	Transcriptional regulator
HUT10_RS29540	COG1175	transmembrane transport
HUT10_RS29545	COG0395	ABC-type sugar transport system, permease component
HUT10_RS29550	COG0789	Transcriptional regulator
HUT10_RS29560	COG4702	Belongs to the UPF0303 family
HUT10_RS29575	COG1473	amidohydrolase
HUT10_RS29615	COG2175	clavaminate synthase activity
HUT10_RS29620	COG4308	Limonene-1,2-epoxide hydrolase catalytic domain
HUT10_RS29665	COG1674	ftsk spoiiie
HUT10_RS29710	COG5479	isomerase activity
HUT10_RS29710	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
HUT10_RS29720	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUT10_RS29740	COG2197	response regulator
HUT10_RS29755	COG0745	RESPONSE REGULATOR receiver
HUT10_RS29760	COG2205	protein histidine kinase activity
HUT10_RS29765	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HUT10_RS29775	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUT10_RS29780	COG1116	anion transmembrane transporter activity
HUT10_RS29830	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HUT10_RS29835	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HUT10_RS29840	COG1705	Flagellar rod assembly protein muramidase FlgJ
HUT10_RS29850	COG1215	transferase activity, transferring glycosyl groups
HUT10_RS29870	COG1216	Glycosyl transferase, family 2
HUT10_RS29885	COG0747	negative chemotaxis
HUT10_RS29900	COG0444	Belongs to the ABC transporter superfamily
HUT10_RS29905	COG4608	Belongs to the ABC transporter superfamily
HUT10_RS29910	COG4941	Belongs to the sigma-70 factor family
HUT10_RS29915	COG3795	YCII-related domain
HUT10_RS29935	COG0697	spore germination
HUT10_RS29940	COG0583	DNA-binding transcription factor activity
HUT10_RS29995	COG1690	Belongs to the RtcB family
HUT10_RS30010	COG2814	Major facilitator Superfamily
HUT10_RS30035	COG1764	response to oxidative stress
HUT10_RS30040	COG0783	Belongs to the Dps family
HUT10_RS30045	COG0076	glutamate decarboxylase activity
HUT10_RS30055	COG1902	pentaerythritol trinitrate reductase activity
HUT10_RS30085	COG1408	metallophosphoesterase
HUT10_RS30095	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HUT10_RS30145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUT10_RS30160	COG0592	DNA-directed DNA polymerase activity
HUT10_RS30210	COG0596	Alpha beta hydrolase
HUT10_RS30220	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HUT10_RS30225	COG3104	oligopeptide transport
HUT10_RS30250	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HUT10_RS30260	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
HUT10_RS30270	COG0640	Transcriptional regulator
HUT10_RS30275	COG2814	Major facilitator Superfamily
HUT10_RS30280	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
HUT10_RS30285	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HUT10_RS30290	COG1737	Transcriptional regulator
HUT10_RS30295	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HUT10_RS30300	COG3876	Protein conserved in bacteria
HUT10_RS30305	COG1472	Belongs to the glycosyl hydrolase 3 family
HUT10_RS30360	COG1111	helicase
HUT10_RS30360	COG1205	dead DEAH box helicase
HUT10_RS30365	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
HUT10_RS30385	COG1754	DNA topoisomerase type I activity
HUT10_RS30385	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HUT10_RS30415	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HUT10_RS30420	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HUT10_RS30495	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HUT10_RS30500	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HUT10_RS30505	COG0483	inositol monophosphate 1-phosphatase activity
HUT10_RS30520	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HUT10_RS30525	COG2027	D-alanyl-D-alanine carboxypeptidase
HUT10_RS30535	COG0037	tRNA processing
HUT10_RS30565	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HUT10_RS30575	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HUT10_RS30590	COG0789	Transcriptional regulator
HUT10_RS30615	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HUT10_RS30620	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HUT10_RS30625	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HUT10_RS30640	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HUT10_RS30670	COG0443	Heat shock 70 kDa protein
HUT10_RS30695	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HUT10_RS30735	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HUT10_RS30760	COG1194	a g-specific adenine glycosylase
HUT10_RS30775	COG1609	Transcriptional regulator
HUT10_RS30780	COG0803	Belongs to the bacterial solute-binding protein 9 family
HUT10_RS30785	COG1120	ATPase activity
HUT10_RS30790	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HUT10_RS30800	COG4399	Belongs to the UPF0754 family
HUT10_RS30815	COG0235	Class ii aldolase
HUT10_RS30860	COG0215	cysteine-tRNA ligase activity
HUT10_RS30875	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
HUT10_RS30880	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
HUT10_RS30885	COG1329	Transcriptional regulator
HUT10_RS30890	COG2847	Copper chaperone PCu(A)C
HUT10_RS30895	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HUT10_RS30935	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
HUT10_RS30970	COG2255	four-way junction helicase activity
HUT10_RS31005	COG0789	Transcriptional regulator
HUT10_RS31040	COG1595	DNA-templated transcription, initiation
HUT10_RS31080	COG0642	Histidine kinase
HUT10_RS31100	COG3795	YCII-related domain
HUT10_RS31105	COG3795	YCII-related domain
HUT10_RS31110	COG4941	Belongs to the sigma-70 factor family
HUT10_RS31120	COG1620	l-lactate permease
HUT10_RS31140	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HUT10_RS31145	COG1492	cobalamin metabolic process
HUT10_RS31155	COG0745	RESPONSE REGULATOR receiver
HUT10_RS31200	COG1832	CoA-binding protein
HUT10_RS31210	COG0346	lactoylglutathione lyase activity
HUT10_RS31225	COG1132	(ABC) transporter
HUT10_RS31310	COG5416	Lipopolysaccharide assembly protein A domain
HUT10_RS31325	COG4399	Belongs to the UPF0754 family
HUT10_RS31330	COG1733	regulation of RNA biosynthetic process
HUT10_RS31340	COG1752	Esterase of the alpha-beta hydrolase superfamily
HUT10_RS31355	COG1917	Cupin 2, conserved barrel domain protein
HUT10_RS31360	COG5285	phytanoyl-CoA dioxygenase
HUT10_RS31365	COG3629	intracellular signal transduction
HUT10_RS31365	COG3903	Transcriptional regulator
HUT10_RS31395	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HUT10_RS31405	COG2971	BadF BadG BcrA BcrD
HUT10_RS31410	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HUT10_RS31420	COG0477	Major facilitator Superfamily
HUT10_RS31425	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HUT10_RS31435	COG0352	thiamine-phosphate diphosphorylase activity
HUT10_RS31440	COG2022	thiamine diphosphate biosynthetic process
HUT10_RS31440	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUT10_RS31450	COG2022	thiamine diphosphate biosynthetic process
HUT10_RS31475	COG0604	alcohol dehydrogenase
HUT10_RS31480	COG1733	regulation of RNA biosynthetic process
HUT10_RS31495	COG0351	phosphomethylpyrimidine kinase
HUT10_RS31500	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HUT10_RS31505	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUT10_RS31515	COG0242	peptide deformylase activity
HUT10_RS31530	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HUT10_RS31540	COG0688	phosphatidylethanolamine metabolic process
HUT10_RS31550	COG2261	transglycosylase associated protein
HUT10_RS31580	COG1278	Cold shock
HUT10_RS31595	COG0459	protein refolding
HUT10_RS31615	COG4948	Mandelate Racemase Muconate Lactonizing
HUT10_RS31620	COG3903	Transcriptional regulator
HUT10_RS31620	COG3629	intracellular signal transduction
HUT10_RS31640	COG1061	Type III restriction enzyme res subunit
HUT10_RS31695	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HUT10_RS31695	COG1116	anion transmembrane transporter activity
HUT10_RS31700	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUT10_RS31715	COG0642	Histidine kinase
HUT10_RS31720	COG2018	Roadblock/LC7 domain
HUT10_RS31735	COG2018	Roadblock/LC7 domain
HUT10_RS31780	COG1388	LysM domain
HUT10_RS31790	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HUT10_RS31795	COG1846	Transcriptional regulator
HUT10_RS31830	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HUT10_RS31835	COG3304	Inner membrane component domain
HUT10_RS31840	COG0384	phenazine biosynthesis protein PhzF
HUT10_RS31865	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HUT10_RS31885	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HUT10_RS31900	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_RS31910	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HUT10_RS31915	COG1309	transcriptional regulator
HUT10_RS31920	COG0546	phosphoglycolate phosphatase activity
HUT10_RS31930	COG1278	Cold shock
HUT10_RS31940	COG2814	Major facilitator Superfamily
HUT10_RS31965	COG2252	PERMEase
HUT10_RS31980	COG2814	Major facilitator Superfamily
HUT10_RS31985	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HUT10_RS31995	COG5398	heme oxygenase
HUT10_RS32010	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUT10_RS32030	COG2205	protein histidine kinase activity
HUT10_RS32035	COG0745	RESPONSE REGULATOR receiver
HUT10_RS32050	COG0577	efflux transmembrane transporter activity
HUT10_RS32050	COG1136	(ABC) transporter
HUT10_RS32055	COG0577	efflux transmembrane transporter activity
HUT10_RS32055	COG1136	(ABC) transporter
HUT10_RS32060	COG1228	amidohydrolase
HUT10_RS32065	COG5650	phosphatidylinositol metabolic process
HUT10_RS32085	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HUT10_RS32090	COG2197	response regulator
HUT10_RS32105	COG1131	(ABC) transporter
HUT10_RS32125	COG0831	urea catabolic process
HUT10_RS32130	COG0832	Belongs to the urease beta subunit family
HUT10_RS32135	COG0804	urea catabolic process
HUT10_RS32145	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HUT10_RS32150	COG0829	nickel cation binding
HUT10_RS32170	COG0259	pyridoxamine-phosphate oxidase activity
HUT10_RS32195	COG1309	transcriptional regulator
HUT10_RS32200	COG2017	converts alpha-aldose to the beta-anomer
HUT10_RS32210	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HUT10_RS32225	COG1960	acyl-CoA dehydrogenase activity
HUT10_RS32245	COG0415	Belongs to the DNA photolyase family
HUT10_RS32255	COG4152	abc transporter atp-binding protein
HUT10_RS32280	COG0277	FAD linked oxidase domain protein
HUT10_RS32300	COG1595	DNA-templated transcription, initiation
HUT10_RS32330	COG0395	ABC-type sugar transport system, permease component
HUT10_RS32335	COG1175	transmembrane transport
HUT10_RS32340	COG2182	Extracellular solute-binding protein
HUT10_RS32355	COG1169	isochorismate synthase
HUT10_RS32390	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_RS32395	COG1024	Enoyl-CoA hydratase
HUT10_RS32415	COG1321	iron dependent repressor
HUT10_RS32450	COG1984	allophanate hydrolase subunit 2
HUT10_RS32465	COG4336	lyase activity
HUT10_RS32470	COG2814	Major facilitator Superfamily
HUT10_RS32480	COG3469	chitinase activity
HUT10_RS32510	COG0747	negative chemotaxis
HUT10_RS32520	COG0601	transmembrane transport
HUT10_RS32525	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUT10_RS32530	COG0444	Belongs to the ABC transporter superfamily
HUT10_RS32545	COG1960	acyl-CoA dehydrogenase activity
HUT10_RS32590	COG2755	lipolytic protein G-D-S-L family
HUT10_RS32590	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HUT10_RS32600	COG0583	DNA-binding transcription factor activity
HUT10_RS32610	COG3285	dna ligase
HUT10_RS32610	COG1793	dna ligase
HUT10_RS32630	COG0438	transferase activity, transferring glycosyl groups
HUT10_RS32645	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUT10_RS32655	COG0483	inositol monophosphate 1-phosphatase activity
HUT10_RS32660	COG2815	serine threonine protein kinase
HUT10_RS32660	COG0515	serine threonine protein kinase
HUT10_RS32665	COG0438	transferase activity, transferring glycosyl groups
HUT10_RS32685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUT10_RS32690	COG0667	Aldo Keto reductase
HUT10_RS32745	COG2197	response regulator
HUT10_RS32750	COG2860	membrane
HUT10_RS32755	COG0745	RESPONSE REGULATOR receiver
HUT10_RS32770	COG1349	DNA-binding transcription factor activity
HUT10_RS32785	COG2801	Transposase and inactivated derivatives
HUT10_RS32820	COG0745	RESPONSE REGULATOR receiver
HUT10_RS32825	COG5002	protein histidine kinase activity
HUT10_RS32830	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HUT10_RS32835	COG0521	Mo-molybdopterin cofactor biosynthetic process
HUT10_RS32835	COG0315	cyclic pyranopterin monophosphate synthase activity
HUT10_RS32865	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HUT10_RS32870	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HUT10_RS32880	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUT10_RS32980	COG1181	Belongs to the D-alanine--D-alanine ligase family
HUT10_RS32985	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HUT10_RS32990	COG2205	protein histidine kinase activity
HUT10_RS32995	COG0745	RESPONSE REGULATOR receiver
HUT10_RS33010	COG0052	Belongs to the universal ribosomal protein uS2 family
HUT10_RS33020	COG2124	cytochrome p450
HUT10_RS33025	COG5001	Diguanylate cyclase
HUT10_RS33030	COG0697	spore germination
HUT10_RS33070	COG1595	DNA-templated transcription, initiation
HUT10_RS33080	COG3284	Transcriptional regulator
HUT10_RS33095	COG2258	MOSC domain
HUT10_RS33130	COG0515	serine threonine protein kinase
HUT10_RS33135	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HUT10_RS33170	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HUT10_RS33195	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HUT10_RS33200	COG0084	hydrolase, TatD family'
HUT10_RS33210	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HUT10_RS33215	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HUT10_RS33220	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HUT10_RS33225	COG0488	(ABC) transporter
HUT10_RS33230	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_RS33240	COG3599	regulation of cell shape
HUT10_RS33245	COG0193	aminoacyl-tRNA hydrolase activity
HUT10_RS33275	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HUT10_RS33305	COG1051	belongs to the nudix hydrolase family
HUT10_RS33310	COG0494	nUDIX hydrolase
HUT10_RS33330	COG2133	pyrroloquinoline quinone binding
HUT10_RS33335	COG2197	response regulator
HUT10_RS33340	COG4585	Histidine kinase
HUT10_RS33350	COG0586	Pfam SNARE associated Golgi protein
HUT10_RS33395	COG1595	DNA-templated transcription, initiation
HUT10_RS33440	COG2837	iron assimilation
HUT10_RS33450	COG0672	)-iron permease
HUT10_RS33470	COG0148	phosphopyruvate hydratase activity
HUT10_RS33495	COG4166	transmembrane transport
HUT10_RS33510	COG0444	Belongs to the ABC transporter superfamily
HUT10_RS33515	COG4608	Belongs to the ABC transporter superfamily
HUT10_RS33545	COG1515	deoxyribonuclease V activity
HUT10_RS33560	COG3979	chitinase
HUT10_RS33610	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
HUT10_RS33620	COG2198	Histidine kinase
HUT10_RS33620	COG2205	protein histidine kinase activity
HUT10_RS33620	COG0784	Response regulator, receiver
HUT10_RS33690	COG3903	Transcriptional regulator
HUT10_RS33690	COG3629	intracellular signal transduction
HUT10_RS33710	COG1132	(ABC) transporter
HUT10_RS33720	COG0148	phosphopyruvate hydratase activity
HUT10_RS33725	COG2205	protein histidine kinase activity
HUT10_RS33740	COG5297	Belongs to the glycosyl hydrolase family 6
HUT10_RS33790	COG0477	Major facilitator Superfamily
HUT10_RS33800	COG0667	Aldo Keto reductase
HUT10_RS33805	COG1472	Belongs to the glycosyl hydrolase 3 family
HUT10_RS33810	COG2197	response regulator
HUT10_RS33820	COG1175	transmembrane transport
HUT10_RS33830	COG2723	6-phospho-beta-galactosidase activity
HUT10_RS33835	COG3629	intracellular signal transduction
HUT10_RS33835	COG3903	Transcriptional regulator
HUT10_RS33900	COG2391	methyltransferase activity
HUT10_RS33905	COG0183	Belongs to the thiolase family
HUT10_RS33950	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HUT10_RS33980	COG3185	4-Hydroxyphenylpyruvate dioxygenase
HUT10_RS33990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUT10_RS33995	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HUT10_RS34005	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HUT10_RS34015	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HUT10_RS34020	COG2226	methyltransferase
HUT10_RS34030	COG1331	Highly conserved protein containing a thioredoxin domain
HUT10_RS34055	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
HUT10_RS34080	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
HUT10_RS34100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUT10_RS34125	COG1793	dna ligase
HUT10_RS34135	COG0114	fumarate hydratase activity
HUT10_RS34140	COG1073	alpha beta
HUT10_RS34150	COG0492	ferredoxin-NADP+ reductase activity
HUT10_RS34165	COG1722	exodeoxyribonuclease VII activity
HUT10_RS34175	COG1570	exodeoxyribonuclease VII activity
HUT10_RS34185	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HUT10_RS34210	COG0419	ATPase involved in DNA repair
HUT10_RS34225	COG0012	GTP binding
HUT10_RS34265	COG2154	pterin-4-alpha-carbinolamine dehydratase
HUT10_RS34280	COG3842	ATPase activity
HUT10_RS34295	COG1131	(ABC) transporter
HUT10_RS34305	COG0745	RESPONSE REGULATOR receiver
HUT10_RS34310	COG2205	protein histidine kinase activity
HUT10_RS34320	COG0180	Tryptophanyl-tRNA synthetase
HUT10_RS34340	COG0747	negative chemotaxis
HUT10_RS34350	COG0601	transmembrane transport
HUT10_RS34365	COG1733	regulation of RNA biosynthetic process
HUT10_RS34370	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS34380	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HUT10_RS34425	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HUT10_RS34430	COG2835	tetraacyldisaccharide 4'-kinase activity
HUT10_RS34440	COG1482	cell wall glycoprotein biosynthetic process
HUT10_RS34445	COG3629	intracellular signal transduction
HUT10_RS34445	COG3903	Transcriptional regulator
HUT10_RS34455	COG0531	amino acid
HUT10_RS34520	COG1414	Transcriptional regulator
HUT10_RS34530	COG0745	RESPONSE REGULATOR receiver
HUT10_RS34535	COG5002	protein histidine kinase activity
HUT10_RS34535	COG5000	phosphorelay sensor kinase activity
HUT10_RS34550	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HUT10_RS34555	COG0653	protein targeting
HUT10_RS34570	COG1011	Hydrolase
HUT10_RS34575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUT10_RS34605	COG1162	GTPase activity
HUT10_RS34610	COG2135	peptidase activity
HUT10_RS34630	COG1595	DNA-templated transcription, initiation
HUT10_RS34650	COG1597	lipid kinase activity
HUT10_RS34665	COG0406	alpha-ribazole phosphatase activity
HUT10_RS34680	COG1846	Transcriptional regulator
HUT10_RS34690	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
HUT10_RS34705	COG0517	IMP dehydrogenase activity
HUT10_RS34705	COG1125	glycine betaine transport
HUT10_RS34710	COG1174	glycine betaine transport
HUT10_RS34715	COG1174	glycine betaine transport
HUT10_RS34740	COG4221	oxidoreductase activity
HUT10_RS34750	COG1280	lysine exporter protein (LysE YggA)
HUT10_RS34755	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_RS34770	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUT10_RS34770	COG0567	Dehydrogenase, E1 component
HUT10_RS34790	COG1132	(ABC) transporter
HUT10_RS34805	COG0745	RESPONSE REGULATOR receiver
HUT10_RS34810	COG0686	Belongs to the AlaDH PNT family
HUT10_RS34830	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HUT10_RS34830	COG2508	Transcriptional regulator
HUT10_RS34835	COG2226	methyltransferase
HUT10_RS34870	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HUT10_RS34880	COG1309	transcriptional regulator
HUT10_RS34885	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HUT10_RS34895	COG2755	lipolytic protein G-D-S-L family
HUT10_RS34900	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUT10_RS34910	COG1960	acyl-CoA dehydrogenase activity
HUT10_RS34945	COG4221	oxidoreductase activity
HUT10_RS35015	COG4974	Belongs to the 'phage' integrase family
HUT10_RS35020	COG1960	acyl-CoA dehydrogenase activity
HUT10_RS35025	COG1960	acyl-CoA dehydrogenase activity
HUT10_RS35090	COG1309	transcriptional regulator
HUT10_RS35095	COG0183	Belongs to the thiolase family
HUT10_RS35100	COG1024	Enoyl-CoA hydratase
HUT10_RS35100	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUT10_RS35105	COG2409	Drug exporters of the RND superfamily
HUT10_RS35110	COG2197	response regulator
HUT10_RS35115	COG4585	Histidine kinase
HUT10_RS35125	COG0477	Major facilitator Superfamily
HUT10_RS35145	COG0028	Belongs to the TPP enzyme family
HUT10_RS35165	COG0667	Aldo Keto reductase
HUT10_RS35185	COG0473	3-isopropylmalate dehydrogenase activity
HUT10_RS35215	COG0154	amidase activity
HUT10_RS35260	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
HUT10_RS35275	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HUT10_RS35285	COG0145	ligase activity
HUT10_RS35295	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS35315	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUT10_RS35320	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HUT10_RS35410	COG2409	Drug exporters of the RND superfamily
HUT10_RS35440	COG0596	Alpha beta hydrolase
HUT10_RS35440	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUT10_RS35470	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_RS35505	COG0596	Alpha beta hydrolase
HUT10_RS35510	COG2801	Transposase and inactivated derivatives
HUT10_RS35510	COG3415	Transposase
HUT10_RS35545	COG0018	arginyl-trna synthetase
HUT10_RS35550	COG0019	diaminopimelate decarboxylase activity
HUT10_RS35555	COG0460	homoserine dehydrogenase
HUT10_RS35560	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HUT10_RS35565	COG0083	homoserine kinase activity
HUT10_RS35575	COG0254	rRNA binding
HUT10_RS35600	COG0463	Glycosyl transferase, family 2
HUT10_RS35605	COG2890	protein-(glutamine-N5) methyltransferase activity
HUT10_RS35620	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HUT10_RS35630	COG0356	it plays a direct role in the translocation of protons across the membrane
HUT10_RS35635	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HUT10_RS35640	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HUT10_RS35645	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HUT10_RS35655	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HUT10_RS35660	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HUT10_RS35665	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HUT10_RS35680	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HUT10_RS35695	COG1309	transcriptional regulator
HUT10_RS35700	COG3631	Ketosteroid isomerase-related protein
HUT10_RS35705	COG0702	epimerase
HUT10_RS35715	COG1280	lysine exporter protein (LysE YggA)
HUT10_RS35720	COG1280	lysine exporter protein (LysE YggA)
HUT10_RS35725	COG1280	lysine exporter protein (LysE YggA)
HUT10_RS35740	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUT10_RS35740	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUT10_RS35745	COG1335	isochorismatase
HUT10_RS35750	COG4977	sequence-specific DNA binding
HUT10_RS35755	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HUT10_RS35775	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
HUT10_RS35805	COG2376	Dihydroxyacetone kinase
HUT10_RS35810	COG1461	Dihydroxyacetone kinase
HUT10_RS35840	COG1522	sequence-specific DNA binding
HUT10_RS35850	COG1522	sequence-specific DNA binding
HUT10_RS35855	COG0626	cystathionine gamma-synthase activity
HUT10_RS35885	COG2267	carboxylic ester hydrolase activity
HUT10_RS35895	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HUT10_RS35900	COG0560	Phosphoserine phosphatase
HUT10_RS35900	COG3830	Belongs to the UPF0237 family
HUT10_RS35930	COG1268	BioY protein
HUT10_RS35940	COG0800	Aldolase
HUT10_RS35945	COG1335	isochorismatase
HUT10_RS35950	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HUT10_RS35965	COG3191	aminopeptidase activity
HUT10_RS35995	COG1794	racemase activity, acting on amino acids and derivatives
HUT10_RS36010	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HUT10_RS36015	COG1234	tRNA 3'-trailer cleavage
HUT10_RS36020	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HUT10_RS36025	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HUT10_RS36070	COG4977	sequence-specific DNA binding
HUT10_RS36105	COG1316	TRANSCRIPTIONal
HUT10_RS36120	COG3706	GGDEF domain
HUT10_RS36130	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS36150	COG2018	Roadblock/LC7 domain
HUT10_RS36165	COG2259	Doxx family
HUT10_RS36175	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUT10_RS36195	COG1408	metallophosphoesterase
HUT10_RS36250	COG2814	Major facilitator Superfamily
HUT10_RS36285	COG0662	Cupin 2, conserved barrel domain protein
HUT10_RS36305	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_RS36310	COG0243	molybdopterin cofactor binding
HUT10_RS36320	COG0596	Alpha beta hydrolase
HUT10_RS36325	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_RS36345	COG1309	transcriptional regulator
HUT10_RS36350	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HUT10_RS36355	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HUT10_RS36415	COG0667	Aldo Keto reductase
HUT10_RS36420	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS36435	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUT10_RS36475	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HUT10_RS36500	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HUT10_RS36520	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_RS36525	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_RS36560	COG0456	acetyltransferase
HUT10_RS36560	COG0454	-acetyltransferase
HUT10_RS36600	COG0745	RESPONSE REGULATOR receiver
HUT10_RS36605	COG4251	negative regulation of phosphorylation
HUT10_RS36610	COG0784	Response regulator, receiver
HUT10_RS36630	COG2837	iron assimilation
HUT10_RS36640	COG0640	Transcriptional regulator
HUT10_RS36660	COG0515	serine threonine protein kinase
HUT10_RS36660	COG2815	serine threonine protein kinase
HUT10_RS36685	COG5002	protein histidine kinase activity
HUT10_RS36690	COG0745	RESPONSE REGULATOR receiver
HUT10_RS36735	COG3226	Transcriptional regulator
HUT10_RS36740	COG1012	belongs to the aldehyde dehydrogenase family
HUT10_RS36780	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUT10_RS36810	COG1472	Belongs to the glycosyl hydrolase 3 family
HUT10_RS36815	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUT10_RS36835	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HUT10_RS36840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUT10_RS36870	COG4981	capsule polysaccharide biosynthetic process
HUT10_RS36895	COG0500	methyltransferase
HUT10_RS36910	COG3655	Transcriptional regulator
HUT10_RS36925	COG2226	methyltransferase
HUT10_RS36935	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUT10_RS36955	COG2814	Major facilitator Superfamily
HUT10_RS36960	COG0789	Transcriptional regulator
HUT10_RS37030	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
HUT10_RS37035	COG0129	dihydroxy-acid dehydratase activity
HUT10_RS37040	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_RS37050	COG1595	DNA-templated transcription, initiation
HUT10_RS37080	COG0604	alcohol dehydrogenase
HUT10_RS37095	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
HUT10_RS37105	COG1609	Transcriptional regulator
HUT10_RS37110	COG1175	transmembrane transport
HUT10_RS37115	COG0395	ABC-type sugar transport system, permease component
HUT10_RS37125	COG3534	alpha-L-arabinofuranosidase
HUT10_RS37155	COG0477	Major facilitator Superfamily
HUT10_RS37170	COG0667	Aldo Keto reductase
HUT10_RS37175	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
HUT10_RS37190	COG0488	(ABC) transporter
HUT10_RS37220	COG2018	Roadblock/LC7 domain
HUT10_RS37265	COG1528	Iron-storage protein
HUT10_RS37275	COG1073	alpha beta
HUT10_RS37290	COG1131	(ABC) transporter
HUT10_RS37295	COG1725	Transcriptional regulator
HUT10_RS37310	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HUT10_RS37325	COG3629	intracellular signal transduction
HUT10_RS37325	COG3903	Transcriptional regulator
HUT10_RS37335	COG0587	DNA-directed DNA polymerase activity
HUT10_RS37340	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS37355	COG1309	transcriptional regulator
HUT10_RS37360	COG4733	cellulase activity
HUT10_RS37360	COG5297	Belongs to the glycosyl hydrolase family 6
HUT10_RS37370	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_RS37375	COG0667	Aldo Keto reductase
HUT10_RS37390	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HUT10_RS37400	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUT10_RS37430	COG3401	FG-GAP repeat protein
HUT10_RS37460	COG0463	Glycosyl transferase, family 2
HUT10_RS37470	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HUT10_RS37485	COG0297	glycogen (starch) synthase activity
HUT10_RS37505	COG0438	transferase activity, transferring glycosyl groups
HUT10_RS37560	COG3345	alpha-galactosidase
HUT10_RS37570	COG1131	(ABC) transporter
HUT10_RS37595	COG4585	Histidine kinase
HUT10_RS37600	COG2197	response regulator
HUT10_RS37630	COG0346	lactoylglutathione lyase activity
HUT10_RS37640	COG1376	ErfK ybiS ycfS ynhG family protein
HUT10_RS37645	COG0477	Major facilitator Superfamily
HUT10_RS37655	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
HUT10_RS37660	COG0433	COG0433 Predicted ATPase
HUT10_RS37670	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HUT10_RS37690	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HUT10_RS37705	COG3469	chitinase activity
HUT10_RS37710	COG2205	protein histidine kinase activity
HUT10_RS37715	COG0745	RESPONSE REGULATOR receiver
HUT10_RS37720	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HUT10_RS37760	COG2801	Transposase and inactivated derivatives
HUT10_RS37760	COG3415	Transposase
HUT10_RS37765	COG1476	TRANSCRIPTIONal
HUT10_RS37775	COG1131	(ABC) transporter
HUT10_RS37805	COG0778	Nitroreductase
HUT10_RS37840	COG1797	cobyrinic acid a,c-diamide synthase activity
HUT10_RS37855	COG2378	regulation of single-species biofilm formation
HUT10_RS37860	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
HUT10_RS37865	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
HUT10_RS37875	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HUT10_RS37880	COG1492	cobalamin metabolic process
HUT10_RS37920	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUT10_RS37930	COG0069	glutamate synthase activity
HUT10_RS37930	COG0067	glutamate synthase
HUT10_RS37930	COG0070	glutamate synthase
HUT10_RS37935	COG1739	Uncharacterized protein family UPF0029
HUT10_RS37940	COG3537	Alpha-1,2-mannosidase
HUT10_RS37945	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUT10_RS37955	COG1522	sequence-specific DNA binding
HUT10_RS37970	COG0559	Belongs to the binding-protein-dependent transport system permease family
HUT10_RS37975	COG0559	Belongs to the binding-protein-dependent transport system permease family
HUT10_RS37995	COG2197	response regulator
HUT10_RS38005	COG0247	lactate metabolic process
HUT10_RS38005	COG0277	FAD linked oxidase domain protein
HUT10_RS38010	COG1309	transcriptional regulator
HUT10_RS38020	COG2124	cytochrome p450
HUT10_RS38025	COG1695	Transcriptional regulator
HUT10_RS38040	COG0235	Class ii aldolase
HUT10_RS38040	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HUT10_RS38050	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HUT10_RS38060	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HUT10_RS38070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUT10_RS38085	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HUT10_RS38105	COG4941	Belongs to the sigma-70 factor family
HUT10_RS38120	COG1309	transcriptional regulator
HUT10_RS38155	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HUT10_RS38160	COG3706	GGDEF domain
HUT10_RS38185	COG1802	Transcriptional regulator
HUT10_RS38195	COG1796	DNA polymerase
HUT10_RS38195	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
HUT10_RS38205	COG1309	transcriptional regulator
HUT10_RS38210	COG2072	flavoprotein involved in K transport
HUT10_RS38225	COG3268	Saccharopine dehydrogenase
HUT10_RS38240	COG1643	Atp-dependent helicase
HUT10_RS38260	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_RS38295	COG1024	Enoyl-CoA hydratase
HUT10_RS38340	COG0583	DNA-binding transcription factor activity
HUT10_RS38345	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
HUT10_RS38365	COG1021	2,3-dihydroxybenzoate-AMP ligase
HUT10_RS38390	COG3835	regulator
HUT10_RS38420	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HUT10_RS38425	COG0531	amino acid
HUT10_RS38460	COG1609	Transcriptional regulator
HUT10_RS38480	COG2130	NADP-dependent
HUT10_RS38490	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS38525	COG0277	FAD linked oxidase domain protein
HUT10_RS38530	COG2226	methyltransferase
HUT10_RS38565	COG0366	Alpha amylase catalytic
HUT10_RS38575	COG1175	transmembrane transport
HUT10_RS38585	COG1609	Transcriptional regulator
HUT10_RS38630	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
HUT10_RS38640	COG4221	oxidoreductase activity
HUT10_RS38645	COG2267	carboxylic ester hydrolase activity
HUT10_RS38665	COG1376	ErfK ybiS ycfS ynhG family protein
HUT10_RS38675	COG0586	Pfam SNARE associated Golgi protein
HUT10_RS38680	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HUT10_RS38695	COG1309	transcriptional regulator
HUT10_RS38705	COG0321	lipoyl(octanoyl) transferase activity
HUT10_RS38720	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUT10_RS38725	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HUT10_RS38735	COG3415	Transposase
HUT10_RS38735	COG2801	Transposase and inactivated derivatives
HUT10_RS38770	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HUT10_RS38795	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
HUT10_RS38805	COG0667	Aldo Keto reductase
HUT10_RS38830	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUT10_RS38840	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HUT10_RS38875	COG1845	cytochrome c oxidase, subunit III
HUT10_RS38880	COG2010	Cytochrome c
HUT10_RS38890	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HUT10_RS38940	COG2124	cytochrome p450
HUT10_RS38945	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HUT10_RS38950	COG0659	secondary active sulfate transmembrane transporter activity
HUT10_RS38955	COG0659	secondary active sulfate transmembrane transporter activity
HUT10_RS38960	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HUT10_RS38980	COG0501	Belongs to the peptidase M48B family
HUT10_RS38985	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HUT10_RS38995	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HUT10_RS39000	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HUT10_RS39005	COG0157	Belongs to the NadC ModD family
HUT10_RS39010	COG1404	Belongs to the peptidase S8 family
HUT10_RS39015	COG2801	Transposase and inactivated derivatives
HUT10_RS39060	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_RS39095	COG1674	ftsk spoiiie
HUT10_RS39120	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HUT10_RS39130	COG5520	Belongs to the glycosyl hydrolase 30 family
HUT10_RS39150	COG4566	intracellular signal transduction
HUT10_RS39155	COG2197	response regulator
HUT10_RS39165	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HUT10_RS39175	COG0131	Imidazoleglycerol-phosphate dehydratase
HUT10_RS39185	COG2409	Drug exporters of the RND superfamily
HUT10_RS39190	COG1309	transcriptional regulator
HUT10_RS39195	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
HUT10_RS39205	COG3959	Transketolase, thiamine diphosphate binding domain
HUT10_RS39225	COG1960	acyl-CoA dehydrogenase activity
HUT10_RS39240	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HUT10_RS39245	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HUT10_RS39250	COG3226	Transcriptional regulator
HUT10_RS39280	COG0107	imidazoleglycerol-phosphate synthase activity
HUT10_RS39325	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HUT10_RS39335	COG0134	indole-3-glycerol-phosphate synthase activity
HUT10_RS39340	COG0133	tryptophan synthase activity
HUT10_RS39345	COG0159	tryptophan synthase activity
HUT10_RS39355	COG0174	glutamine synthetase
HUT10_RS39370	COG1473	amidohydrolase
HUT10_RS39375	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HUT10_RS39385	COG0069	glutamate synthase activity
HUT10_RS39385	COG0067	glutamate synthase
HUT10_RS39385	COG0070	glutamate synthase
HUT10_RS39420	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
HUT10_RS39445	COG2268	Band 7 protein
HUT10_RS39455	COG2815	serine threonine protein kinase
HUT10_RS39455	COG0515	serine threonine protein kinase
HUT10_RS39545	COG0242	peptide deformylase activity
HUT10_RS39555	COG1349	DNA-binding transcription factor activity
HUT10_RS39565	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HUT10_RS39570	COG0443	Heat shock 70 kDa protein
HUT10_RS39580	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HUT10_RS39585	COG2137	regulation of response to DNA damage stimulus
HUT10_RS39600	COG0800	Aldolase
HUT10_RS39620	COG1053	succinate dehydrogenase
HUT10_RS39635	COG1228	amidohydrolase
HUT10_RS39670	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS39675	COG0765	amino acid transport
HUT10_RS39680	COG0765	amino acid transport
HUT10_RS39685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUT10_RS39690	COG1126	abc transporter atp-binding protein
HUT10_RS39700	COG0642	Histidine kinase
HUT10_RS39715	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS39715	COG0604	alcohol dehydrogenase
HUT10_RS39715	COG3321	synthase
HUT10_RS39785	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HUT10_RS39800	COG1196	nuclear chromosome segregation
HUT10_RS39805	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HUT10_RS39815	COG0525	valine-tRNA ligase activity
HUT10_RS39830	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HUT10_RS39840	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HUT10_RS39850	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HUT10_RS39880	COG1505	serine-type exopeptidase activity
HUT10_RS39920	COG2936	dipeptidyl-peptidase activity
HUT10_RS39925	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HUT10_RS39935	COG2197	response regulator
HUT10_RS39955	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HUT10_RS39960	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HUT10_RS39975	COG0123	including yeast histone deacetylase and acetoin utilization protein
HUT10_RS39990	COG1960	acyl-CoA dehydrogenase activity
HUT10_RS39995	COG1960	acyl-CoA dehydrogenase activity
HUT10_RS40005	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS40015	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HUT10_RS40020	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HUT10_RS40075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUT10_RS40090	COG1609	Transcriptional regulator
HUT10_RS40105	COG0395	ABC-type sugar transport system, permease component
HUT10_RS40120	COG1022	Amp-dependent synthetase and ligase
HUT10_RS40140	COG0003	Pfam Anion-transporting ATPase
HUT10_RS40150	COG1940	carbohydrate kinase activity
HUT10_RS40160	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
HUT10_RS40185	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HUT10_RS40210	COG1733	regulation of RNA biosynthetic process
HUT10_RS40215	COG0640	Transcriptional regulator
HUT10_RS40240	COG1946	Acyl-CoA thioesterase
HUT10_RS40260	COG1672	PFAM Archaeal ATPase
HUT10_RS40260	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
HUT10_RS40265	COG1012	belongs to the aldehyde dehydrogenase family
HUT10_RS40280	COG1960	acyl-CoA dehydrogenase activity
HUT10_RS40285	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUT10_RS40330	COG1309	transcriptional regulator
HUT10_RS40335	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUT10_RS40350	COG2018	Roadblock/LC7 domain
HUT10_RS40365	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HUT10_RS40385	COG1703	isobutyryl-CoA mutase activity
HUT10_RS40385	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUT10_RS40385	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
HUT10_RS40390	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_RS40400	COG1309	transcriptional regulator
HUT10_RS40405	COG1960	acyl-CoA dehydrogenase activity
HUT10_RS40410	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HUT10_RS40430	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT10_RS40435	COG0748	coenzyme F420 binding
HUT10_RS40445	COG1960	acyl-CoA dehydrogenase activity
HUT10_RS40450	COG1960	acyl-CoA dehydrogenase activity
HUT10_RS40455	COG2030	dehydratase
HUT10_RS40475	COG0196	riboflavin kinase activity
HUT10_RS40480	COG2030	dehydratase
HUT10_RS40510	COG1960	acyl-CoA dehydrogenase activity
HUT10_RS40515	COG2267	carboxylic ester hydrolase activity
HUT10_RS40520	COG0346	lactoylglutathione lyase activity
HUT10_RS40525	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HUT10_RS40550	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HUT10_RS40580	COG0477	Major facilitator Superfamily
HUT10_RS40585	COG0446	pyridine nucleotide-disulphide oxidoreductase
HUT10_RS40635	COG1473	amidohydrolase
HUT10_RS40645	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUT10_RS40650	COG1228	amidohydrolase
HUT10_RS40655	COG0596	Alpha beta hydrolase
HUT10_RS40660	COG0251	oxidation-reduction process
HUT10_RS40665	COG0183	Belongs to the thiolase family
HUT10_RS40670	COG2124	cytochrome p450
HUT10_RS40685	COG1295	ribonuclease BN
HUT10_RS40725	COG2070	2-Nitropropane dioxygenase
HUT10_RS40740	COG2188	Transcriptional regulator
HUT10_RS40760	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HUT10_RS40760	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HUT10_RS40770	COG1490	D-aminoacyl-tRNA deacylase activity
HUT10_RS40780	COG1473	amidohydrolase
HUT10_RS40795	COG2313	pseudouridylate synthase activity
HUT10_RS40820	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HUT10_RS40830	COG1061	Type III restriction enzyme res subunit
HUT10_RS40835	COG4213	ABC transporter substrate-binding protein
HUT10_RS40845	COG4214	carbohydrate transport
HUT10_RS40875	COG0531	amino acid
HUT10_RS40920	COG0366	Alpha amylase catalytic
HUT10_RS40925	COG0366	Alpha amylase catalytic
HUT10_RS40935	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HUT10_RS40950	COG1940	carbohydrate kinase activity
HUT10_RS40955	COG0483	inositol monophosphate 1-phosphatase activity
HUT10_RS40975	COG0756	dUTP diphosphatase activity
HUT10_RS41005	COG0569	domain protein
HUT10_RS41010	COG0531	amino acid
HUT10_RS41015	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HUT10_RS41030	COG1012	belongs to the aldehyde dehydrogenase family
HUT10_RS41035	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HUT10_RS41045	COG1012	belongs to the aldehyde dehydrogenase family
HUT10_RS41050	COG0028	Belongs to the TPP enzyme family
HUT10_RS41070	COG0745	RESPONSE REGULATOR receiver
HUT10_RS41075	COG2205	protein histidine kinase activity
HUT10_RS41095	COG1024	Enoyl-CoA hydratase
HUT10_RS41095	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUT10_RS41100	COG0183	Belongs to the thiolase family
HUT10_RS41145	COG1309	transcriptional regulator
HUT10_RS41160	COG2197	response regulator
HUT10_RS41170	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HUT10_RS41185	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUT10_RS41205	COG3220	belongs to the UPF0276 family
HUT10_RS41220	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HUT10_RS41255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_RS41260	COG0539	negative regulation of cytoplasmic translation
HUT10_RS41270	COG2508	Transcriptional regulator
HUT10_RS41270	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HUT10_RS41275	COG1012	belongs to the aldehyde dehydrogenase family
HUT10_RS41280	COG0506	proline dehydrogenase activity
HUT10_RS41285	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HUT10_RS41300	COG4941	Belongs to the sigma-70 factor family
HUT10_RS41310	COG1793	dna ligase
HUT10_RS41340	COG1302	Protein conserved in bacteria
HUT10_RS41350	COG1595	DNA-templated transcription, initiation
HUT10_RS41385	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HUT10_RS41390	COG0640	Transcriptional regulator
HUT10_RS41400	COG2326	polyphosphate kinase activity
HUT10_RS41420	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HUT10_RS41425	COG1993	acr, cog1993
HUT10_RS41430	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HUT10_RS41450	COG0174	glutamine synthetase
HUT10_RS41460	COG1672	PFAM Archaeal ATPase
HUT10_RS41460	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
HUT10_RS41480	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HUT10_RS41505	COG2124	cytochrome p450
HUT10_RS41525	COG2084	Dehydrogenase
HUT10_RS41540	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HUT10_RS41550	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HUT10_RS41555	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HUT10_RS41560	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HUT10_RS41565	COG1309	transcriptional regulator
HUT10_RS41575	COG1073	alpha beta
HUT10_RS41600	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HUT10_RS41605	COG1263	PTS System
HUT10_RS41610	COG2188	Transcriptional regulator
HUT10_RS41615	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUT10_RS41620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUT10_RS41620	COG1263	PTS System
HUT10_RS41620	COG2190	(PTS) system
HUT10_RS41645	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HUT10_RS41650	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HUT10_RS41655	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HUT10_RS41660	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
HUT10_RS41665	COG0346	lactoylglutathione lyase activity
HUT10_RS41685	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HUT10_RS41690	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HUT10_RS41705	COG0540	Belongs to the ATCase OTCase family
HUT10_RS41720	COG0505	Belongs to the CarA family
HUT10_RS41730	COG0284	orotidine-5'-phosphate decarboxylase activity
HUT10_RS41740	COG0194	GDP metabolic process
HUT10_RS41745	COG1758	RNA polymerase activity
HUT10_RS41755	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HUT10_RS41790	COG0405	Gamma-glutamyltransferase
HUT10_RS41795	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HUT10_RS41820	COG2197	response regulator
HUT10_RS41825	COG4585	Histidine kinase
HUT10_RS41840	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUT10_RS41840	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUT10_RS41845	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
HUT10_RS41865	COG0322	excinuclease ABC activity
HUT10_RS41870	COG1660	Displays ATPase and GTPase activities
HUT10_RS41880	COG1481	regulation of sporulation
HUT10_RS41885	COG0463	Glycosyl transferase, family 2
HUT10_RS41910	COG3250	beta-galactosidase activity
HUT10_RS41915	COG0408	coproporphyrinogen oxidase activity
HUT10_RS41950	COG1280	lysine exporter protein (LysE YggA)
HUT10_RS41960	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HUT10_RS41965	COG0126	phosphoglycerate kinase activity
HUT10_RS41970	COG0149	triose-phosphate isomerase activity
HUT10_RS42000	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS42005	COG0363	glucosamine-6-phosphate deaminase activity
HUT10_RS42020	COG0166	Belongs to the GPI family
HUT10_RS42025	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HUT10_RS42035	COG0109	protoheme IX farnesyltransferase activity
HUT10_RS42100	COG3415	Transposase
HUT10_RS42100	COG2801	Transposase and inactivated derivatives
HUT10_RS42140	COG0396	ATPase activity
HUT10_RS42155	COG2151	metal-sulfur cluster biosynthetic enzyme
HUT10_RS42165	COG1742	UPF0060 membrane protein
HUT10_RS42175	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HUT10_RS42225	COG2199	diguanylate cyclase activity
HUT10_RS42225	COG2200	EAL domain
HUT10_RS42245	COG0232	Belongs to the dGTPase family. Type 2 subfamily
HUT10_RS42260	COG0488	(ABC) transporter
HUT10_RS42285	COG1132	(ABC) transporter
HUT10_RS42295	COG4821	SIS domain
HUT10_RS42305	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HUT10_RS42310	COG1316	TRANSCRIPTIONal
HUT10_RS42315	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HUT10_RS42325	COG5001	Diguanylate cyclase
HUT10_RS42325	COG3300	MHYT domain
HUT10_RS42345	COG0494	nUDIX hydrolase
HUT10_RS42355	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HUT10_RS42355	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HUT10_RS42365	COG1024	Enoyl-CoA hydratase
HUT10_RS42380	COG1960	acyl-CoA dehydrogenase activity
HUT10_RS42385	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUT10_RS42400	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS42430	COG3469	chitinase activity
HUT10_RS42435	COG3706	GGDEF domain
HUT10_RS42465	COG1309	transcriptional regulator
HUT10_RS42470	COG1376	ErfK ybiS ycfS ynhG family protein
HUT10_RS42505	COG4585	Histidine kinase
HUT10_RS42510	COG2197	response regulator
HUT10_RS42530	COG1120	ATPase activity
HUT10_RS42620	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HUT10_RS42635	COG1846	Transcriptional regulator
HUT10_RS42650	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HUT10_RS42665	COG1595	DNA-templated transcription, initiation
HUT10_RS42675	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HUT10_RS42690	COG1799	cell septum assembly
HUT10_RS42710	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HUT10_RS42715	COG0768	penicillin binding
HUT10_RS42720	COG0640	Transcriptional regulator
HUT10_RS42730	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HUT10_RS42740	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HUT10_RS42765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_RS42775	COG0248	Ppx GppA phosphatase
HUT10_RS42820	COG3415	Transposase
HUT10_RS42820	COG2801	Transposase and inactivated derivatives
HUT10_RS42835	COG1846	Transcriptional regulator
HUT10_RS42835	COG1940	carbohydrate kinase activity
HUT10_RS42880	COG1309	transcriptional regulator
HUT10_RS42885	COG4221	oxidoreductase activity
HUT10_RS42890	COG0667	Aldo Keto reductase
HUT10_RS42895	COG0542	response to heat
HUT10_RS42905	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HUT10_RS42915	COG0514	ATP-dependent DNA helicase (RecQ)
HUT10_RS42925	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS42960	COG2205	protein histidine kinase activity
HUT10_RS42965	COG0745	RESPONSE REGULATOR receiver
HUT10_RS43045	COG0604	alcohol dehydrogenase
HUT10_RS43055	COG2764	glyoxalase bleomycin resistance protein dioxygenase
HUT10_RS43080	COG4585	Histidine kinase
HUT10_RS43090	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HUT10_RS43095	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HUT10_RS43100	COG2080	2 iron, 2 sulfur cluster binding
HUT10_RS43125	COG2188	Transcriptional regulator
HUT10_RS43140	COG2172	sigma factor antagonist activity
HUT10_RS43145	COG1366	Belongs to the anti-sigma-factor antagonist family
HUT10_RS43150	COG1366	Belongs to the anti-sigma-factor antagonist family
HUT10_RS43165	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS43170	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HUT10_RS43185	COG3546	catalase activity
HUT10_RS43195	COG0702	epimerase
HUT10_RS43200	COG1733	regulation of RNA biosynthetic process
HUT10_RS43215	COG1609	Transcriptional regulator
HUT10_RS43225	COG1175	transmembrane transport
HUT10_RS43230	COG0395	ABC-type sugar transport system, permease component
HUT10_RS43250	COG0667	Aldo Keto reductase
HUT10_RS43275	COG0667	Aldo Keto reductase
HUT10_RS43295	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HUT10_RS43300	COG1691	(AIR) carboxylase
HUT10_RS43305	COG3875	lactate racemase activity
HUT10_RS43310	COG3618	amidohydrolase
HUT10_RS43315	COG0179	Fumarylacetoacetate (FAA) hydrolase
HUT10_RS43320	COG4948	Mandelate Racemase Muconate Lactonizing
HUT10_RS43325	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS43335	COG1129	ABC transporter
HUT10_RS43385	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_RS43405	COG3251	PFAM MbtH domain protein
HUT10_RS43425	COG2124	cytochrome p450
HUT10_RS43485	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS43500	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_RS43520	COG0583	DNA-binding transcription factor activity
HUT10_RS43530	COG4221	oxidoreductase activity
HUT10_RS43535	COG0583	DNA-binding transcription factor activity
HUT10_RS43545	COG4948	Mandelate Racemase Muconate Lactonizing
HUT10_RS43550	COG0395	ABC-type sugar transport system, permease component
HUT10_RS43555	COG3833	ABC-type maltose transport systems, permease component
HUT10_RS43595	COG2175	clavaminate synthase activity
HUT10_RS43600	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS43600	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT10_RS43600	COG4221	oxidoreductase activity
HUT10_RS43600	COG3321	synthase
HUT10_RS43650	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HUT10_RS43685	COG2018	Roadblock/LC7 domain
HUT10_RS43690	COG5002	protein histidine kinase activity
HUT10_RS43720	COG1940	carbohydrate kinase activity
HUT10_RS43730	COG1129	ABC transporter
HUT10_RS43735	COG1172	Belongs to the binding-protein-dependent transport system permease family
HUT10_RS43745	COG0673	inositol 2-dehydrogenase activity
HUT10_RS43810	COG0793	Belongs to the peptidase S41A family
HUT10_RS43810	COG4946	Tricorn protease homolog
HUT10_RS43840	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUT10_RS43885	COG0736	holo-[acyl-carrier-protein] synthase activity
HUT10_RS43900	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_RS43905	COG1131	(ABC) transporter
HUT10_RS43960	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUT10_RS43980	COG0019	diaminopimelate decarboxylase activity
HUT10_RS43985	COG3903	Transcriptional regulator
HUT10_RS43985	COG3629	intracellular signal transduction
HUT10_RS43995	COG0747	negative chemotaxis
HUT10_RS44005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUT10_RS44025	COG0604	alcohol dehydrogenase
HUT10_RS44065	COG0702	epimerase
HUT10_RS44070	COG1733	regulation of RNA biosynthetic process
HUT10_RS44080	COG1012	belongs to the aldehyde dehydrogenase family
HUT10_RS44130	COG0765	amino acid transport
HUT10_RS44145	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HUT10_RS44175	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_RS44190	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
HUT10_RS44195	COG1472	Belongs to the glycosyl hydrolase 3 family
HUT10_RS44215	COG2508	Transcriptional regulator
HUT10_RS44220	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUT10_RS44230	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUT10_RS44235	COG1215	transferase activity, transferring glycosyl groups
HUT10_RS44245	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_RS44255	COG3158	transport of potassium into the cell
HUT10_RS44260	COG0438	transferase activity, transferring glycosyl groups
HUT10_RS44260	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HUT10_RS44270	COG2205	protein histidine kinase activity
HUT10_RS44280	COG3629	intracellular signal transduction
HUT10_RS44280	COG3903	Transcriptional regulator
HUT10_RS44300	COG1335	isochorismatase
HUT10_RS44330	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS44350	COG3629	intracellular signal transduction
HUT10_RS44350	COG3903	Transcriptional regulator
HUT10_RS44355	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HUT10_RS44370	COG2197	response regulator
HUT10_RS44380	COG1136	(ABC) transporter
HUT10_RS44380	COG0577	efflux transmembrane transporter activity
HUT10_RS44390	COG0445	tRNA wobble uridine modification
HUT10_RS44440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HUT10_RS44465	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUT10_RS44470	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUT10_RS44475	COG3629	intracellular signal transduction
HUT10_RS44475	COG3903	Transcriptional regulator
HUT10_RS44480	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HUT10_RS44495	COG3509	depolymerase
HUT10_RS44505	COG0583	DNA-binding transcription factor activity
HUT10_RS44670	COG2124	cytochrome p450
HUT10_RS44675	COG2867	negative regulation of translational initiation
HUT10_RS44675	COG2226	methyltransferase
HUT10_RS44680	COG0662	Cupin 2, conserved barrel domain protein
HUT10_RS44730	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUT10_RS44735	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HUT10_RS44740	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUT10_RS44750	COG0395	ABC-type sugar transport system, permease component
HUT10_RS44765	COG1609	Transcriptional regulator
HUT10_RS44850	COG3831	ATPase activity
HUT10_RS44870	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_RS44880	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
HUT10_RS44890	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HUT10_RS44895	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HUT10_RS44900	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
HUT10_RS44905	COG1012	belongs to the aldehyde dehydrogenase family
HUT10_RS44910	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HUT10_RS44940	COG3661	Belongs to the glycosyl hydrolase 67 family
HUT10_RS44995	COG2201	protein-glutamate methylesterase activity
HUT10_RS45010	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HUT10_RS45085	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_RS45090	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
HUT10_RS45110	COG0702	epimerase
HUT10_RS45140	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
HUT10_RS45155	COG4948	Mandelate Racemase Muconate Lactonizing
HUT10_RS45180	COG0444	Belongs to the ABC transporter superfamily
HUT10_RS45185	COG4608	Belongs to the ABC transporter superfamily
HUT10_RS45195	COG0477	Major facilitator Superfamily
HUT10_RS45225	COG0477	Major facilitator Superfamily
HUT10_RS45235	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HUT10_RS45245	COG3629	intracellular signal transduction
HUT10_RS45245	COG3903	Transcriptional regulator
HUT10_RS45250	COG3507	Belongs to the glycosyl hydrolase 43 family
HUT10_RS45265	COG0235	Class ii aldolase
HUT10_RS45270	COG0701	Predicted permease
HUT10_RS45305	COG0366	Alpha amylase catalytic
HUT10_RS45305	COG1470	cell adhesion involved in biofilm formation
HUT10_RS45315	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_RS45330	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUT10_RS45330	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUT10_RS45350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUT10_RS45375	COG2080	2 iron, 2 sulfur cluster binding
HUT10_RS45380	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HUT10_RS45385	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HUT10_RS45445	COG3629	intracellular signal transduction
HUT10_RS45445	COG3903	Transcriptional regulator
HUT10_RS45485	COG2076	Multidrug Resistance protein
HUT10_RS45505	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HUT10_RS45515	COG0745	RESPONSE REGULATOR receiver
HUT10_RS45520	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_RS45530	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HUT10_RS45535	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUT10_RS45550	COG4172	Belongs to the ABC transporter superfamily
HUT10_RS45560	COG1309	transcriptional regulator
HUT10_RS45565	COG2957	Belongs to the agmatine deiminase family
HUT10_RS45570	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS45580	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUT10_RS45590	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUT10_RS45590	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUT10_RS45595	COG2197	response regulator
HUT10_RS45605	COG1131	(ABC) transporter
HUT10_RS45620	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HUT10_RS45625	COG4279	zinc finger
HUT10_RS45670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_RS45690	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HUT10_RS45725	COG3118	belongs to the thioredoxin family
HUT10_RS45730	COG0542	response to heat
HUT10_RS45740	COG0484	heat shock protein binding
HUT10_RS45745	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HUT10_RS45750	COG0443	Heat shock 70 kDa protein
HUT10_RS45770	COG0366	Alpha amylase catalytic
HUT10_RS45830	COG1595	DNA-templated transcription, initiation
HUT10_RS45860	COG3693	PFAM glycoside hydrolase, family 10
HUT10_RS45890	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HUT10_RS45900	COG1063	alcohol dehydrogenase
HUT10_RS45905	COG0300	oxidoreductase activity
HUT10_RS45910	COG1309	transcriptional regulator
HUT10_RS45920	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT10_RS45930	COG0542	response to heat
HUT10_RS45935	COG1271	oxidase subunit
HUT10_RS45940	COG1294	oxidase, subunit
HUT10_RS45970	COG1595	DNA-templated transcription, initiation
HUT10_RS45980	COG1404	Belongs to the peptidase S8 family
HUT10_RS45990	COG3246	L-lysine catabolic process to acetate
HUT10_RS46015	COG0477	Major facilitator Superfamily
HUT10_RS46040	COG0583	DNA-binding transcription factor activity
HUT10_RS46105	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS46115	COG3321	synthase
HUT10_RS46115	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT10_RS46115	COG0300	oxidoreductase activity
HUT10_RS46115	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS46115	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_RS46120	COG0300	oxidoreductase activity
HUT10_RS46120	COG0318	PFAM AMP-dependent synthetase and ligase
HUT10_RS46120	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS46120	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT10_RS46120	COG3321	synthase
HUT10_RS46125	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT10_RS46125	COG3321	synthase
HUT10_RS46125	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HUT10_RS46125	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HUT10_RS46125	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS46160	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT10_RS46160	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS46160	COG3321	synthase
HUT10_RS46160	COG4221	oxidoreductase activity
HUT10_RS46185	COG0488	(ABC) transporter
HUT10_RS46195	COG0659	secondary active sulfate transmembrane transporter activity
HUT10_RS46210	COG0596	Alpha beta hydrolase
HUT10_RS46235	COG3629	intracellular signal transduction
HUT10_RS46235	COG3903	Transcriptional regulator
HUT10_RS46275	COG4249	Peptidase C14 caspase catalytic subunit p20
HUT10_RS46275	COG2319	Wd-40 repeat
HUT10_RS46290	COG0714	Associated with various cellular activities
HUT10_RS46300	COG3629	intracellular signal transduction
HUT10_RS46350	COG0702	epimerase
HUT10_RS46395	COG2205	protein histidine kinase activity
HUT10_RS46400	COG0745	RESPONSE REGULATOR receiver
HUT10_RS46450	COG4978	Transcriptional regulator
HUT10_RS46450	COG0789	Transcriptional regulator
HUT10_RS46530	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS46680	COG0302	gtp cyclohydrolase
HUT10_RS46685	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS46690	COG1819	glycosyl
HUT10_RS46705	COG0702	epimerase
HUT10_RS46825	COG0309	Hydrogenase expression formation protein (HypE)
HUT10_RS46830	COG0409	Hydrogenase expression formation protein
HUT10_RS46835	COG0298	carbon dioxide binding
HUT10_RS46920	COG2205	protein histidine kinase activity
HUT10_RS46940	COG1846	Transcriptional regulator
HUT10_RS46950	COG1830	Aldolase
HUT10_RS46960	COG0674	pyruvate-flavodoxin oxidoreductase activity
HUT10_RS46965	COG1013	pyruvate-flavodoxin oxidoreductase activity
HUT10_RS46970	COG0493	'glutamate synthase
HUT10_RS46985	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
HUT10_RS47005	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HUT10_RS47045	COG2326	polyphosphate kinase activity
HUT10_RS47060	COG0589	response to stress
HUT10_RS47065	COG2239	Acts as a magnesium transporter
HUT10_RS47105	COG0516	GMP reductase activity
HUT10_RS47105	COG0517	IMP dehydrogenase activity
HUT10_RS47115	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
HUT10_RS47135	COG4988	ABC transporter
HUT10_RS47140	COG1294	oxidase, subunit
HUT10_RS47175	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HUT10_RS47215	COG0574	Belongs to the PEP-utilizing enzyme family
HUT10_RS47215	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HUT10_RS47220	COG1131	(ABC) transporter
HUT10_RS47225	COG3559	Exporter of polyketide antibiotics
HUT10_RS47240	COG2239	Acts as a magnesium transporter
HUT10_RS47250	COG0589	response to stress
HUT10_RS47265	COG1063	alcohol dehydrogenase
HUT10_RS47315	COG0330	HflC and HflK could
HUT10_RS47320	COG1252	NADH dehydrogenase
HUT10_RS47435	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HUT10_RS47465	COG3250	beta-galactosidase activity
HUT10_RS47480	COG0583	DNA-binding transcription factor activity
HUT10_RS47490	COG0477	Major facilitator Superfamily
HUT10_RS47520	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
HUT10_RS47545	COG0778	Nitroreductase
HUT10_RS47570	COG0477	Major facilitator Superfamily
HUT10_RS47585	COG0300	oxidoreductase activity
HUT10_RS47605	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT10_RS47620	COG1250	3-hydroxyacyl-CoA dehydrogenase
HUT10_RS47630	COG1960	acyl-CoA dehydrogenase activity
HUT10_RS47665	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS47710	COG0656	L-ascorbic acid biosynthetic process
HUT10_RS47720	COG1063	alcohol dehydrogenase
HUT10_RS47745	COG3903	Transcriptional regulator
HUT10_RS47745	COG3629	intracellular signal transduction
HUT10_RS47755	COG2205	protein histidine kinase activity
HUT10_RS47780	COG0438	transferase activity, transferring glycosyl groups
HUT10_RS47790	COG0667	Aldo Keto reductase
HUT10_RS47830	COG3629	intracellular signal transduction
HUT10_RS47830	COG3903	Transcriptional regulator
HUT10_RS47835	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HUT10_RS47870	COG2226	methyltransferase
HUT10_RS47880	COG0640	Transcriptional regulator
HUT10_RS47885	COG0798	PFAM Bile acid sodium symporter
HUT10_RS47895	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HUT10_RS47905	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HUT10_RS47910	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
HUT10_RS47915	COG0235	Class ii aldolase
HUT10_RS47915	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
HUT10_RS47920	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HUT10_RS47930	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HUT10_RS47955	COG2226	methyltransferase
HUT10_RS47970	COG1181	Belongs to the D-alanine--D-alanine ligase family
HUT10_RS47980	COG0243	molybdopterin cofactor binding
HUT10_RS48060	COG0789	Transcriptional regulator
HUT10_RS48110	COG0494	nUDIX hydrolase
HUT10_RS48260	COG0714	Associated with various cellular activities
HUT10_RS48285	COG3883	PFAM NLP P60 protein
HUT10_RS48285	COG0791	NLP P60 protein
HUT10_RS48340	COG1063	alcohol dehydrogenase
HUT10_RS48400	COG1672	PFAM Archaeal ATPase
HUT10_RS48400	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
HUT10_RS48425	COG1802	Transcriptional regulator
HUT10_RS48430	COG1063	alcohol dehydrogenase
HUT10_RS48460	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HUT10_RS48475	COG1733	regulation of RNA biosynthetic process
HUT10_RS48480	COG1335	isochorismatase
HUT10_RS48490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HUT10_RS48505	COG1942	4-Oxalocrotonate Tautomerase
HUT10_RS48515	COG3971	2-oxopent-4-enoate hydratase activity
HUT10_RS48535	COG1355	regulation of microtubule-based process
HUT10_RS48560	COG0300	oxidoreductase activity
HUT10_RS48565	COG2814	Major facilitator Superfamily
HUT10_RS48580	COG0006	proline dipeptidase activity
HUT10_RS48590	COG1609	Transcriptional regulator
HUT10_RS48610	COG0508	dehydrogenase complex catalyzes the overall conversion of
HUT10_RS48615	COG0402	S-adenosylhomocysteine deaminase activity
HUT10_RS48620	COG1012	belongs to the aldehyde dehydrogenase family
HUT10_RS48665	COG1196	nuclear chromosome segregation
HUT10_RS48715	COG0778	Nitroreductase
HUT10_RS48720	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HUT10_RS48745	COG0438	transferase activity, transferring glycosyl groups
HUT10_RS48770	COG3608	succinylglutamate desuccinylase aspartoacylase
HUT10_RS48770	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HUT10_RS48780	COG0277	FAD linked oxidase domain protein
HUT10_RS48790	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HUT10_RS48805	COG1396	sequence-specific DNA binding
HUT10_RS48820	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HUT10_RS48825	COG0217	transcriptional regulatory protein
HUT10_RS48845	COG0632	four-way junction helicase activity
HUT10_RS48850	COG2255	four-way junction helicase activity
HUT10_RS48855	COG1862	Preprotein translocase
HUT10_RS48865	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HUT10_RS48870	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HUT10_RS48875	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HUT10_RS48880	COG0402	S-adenosylhomocysteine deaminase activity
HUT10_RS48915	COG1073	alpha beta
HUT10_RS48935	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HUT10_RS48940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HUT10_RS48970	COG3629	intracellular signal transduction
HUT10_RS48970	COG3903	Transcriptional regulator
HUT10_RS49005	COG2205	protein histidine kinase activity
HUT10_RS49010	COG2018	Roadblock/LC7 domain
HUT10_RS49030	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HUT10_RS49045	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HUT10_RS49090	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUT10_RS49120	COG1472	Belongs to the glycosyl hydrolase 3 family
HUT10_RS49195	COG3209	COG3209 Rhs family protein
HUT10_RS49205	COG0477	Major facilitator Superfamily
HUT10_RS49225	COG3973	AAA domain
HUT10_RS49225	COG3973	AAA domain
HUT10_RS49240	COG0019	diaminopimelate decarboxylase activity
HUT10_RS49245	COG0583	DNA-binding transcription factor activity
HUT10_RS49285	COG0656	L-ascorbic acid biosynthetic process
HUT10_RS49315	COG2172	sigma factor antagonist activity
HUT10_RS49350	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HUT10_RS49355	COG1573	uracil-dna glycosylase
HUT10_RS49370	COG0129	dihydroxy-acid dehydratase activity
HUT10_RS49380	COG0395	ABC-type sugar transport system, permease component
HUT10_RS49400	COG5297	Belongs to the glycosyl hydrolase family 6
HUT10_RS49400	COG4733	cellulase activity
HUT10_RS49405	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HUT10_RS49410	COG5297	Belongs to the glycosyl hydrolase family 6
HUT10_RS49415	COG0456	acetyltransferase
HUT10_RS49440	COG0667	Aldo Keto reductase
HUT10_RS49445	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
HUT10_RS49480	COG2814	Major facilitator Superfamily
HUT10_RS49510	COG1324	tolerance protein
HUT10_RS49525	COG2197	response regulator
HUT10_RS49535	COG4585	Histidine kinase
HUT10_RS49540	COG2201	protein-glutamate methylesterase activity
HUT10_RS49585	COG0019	diaminopimelate decarboxylase activity
HUT10_RS49590	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HUT10_RS49610	COG2409	Drug exporters of the RND superfamily
HUT10_RS49620	COG0667	Aldo Keto reductase
HUT10_RS49640	COG2770	Histidine kinase
HUT10_RS49640	COG2208	phosphoserine phosphatase activity
HUT10_RS49685	COG1309	transcriptional regulator
HUT10_RS49690	COG0596	Alpha beta hydrolase
HUT10_RS49700	COG1309	transcriptional regulator
HUT10_RS49725	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUT10_RS49725	COG0300	oxidoreductase activity
HUT10_RS49725	COG1028	Short-chain dehydrogenase reductase Sdr
HUT10_RS49725	COG3321	synthase
HUT10_RS49725	COG0318	PFAM AMP-dependent synthetase and ligase