locus-tag	class	description
YIM_RS00015	COG0592	DNA-directed DNA polymerase activity
YIM_RS00020	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
YIM_RS00025	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
YIM_RS00030	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
YIM_RS00035	COG0187	DNA topoisomerase II activity
YIM_RS00040	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
YIM_RS00145	COG3764	Sortase (surface protein transpeptidase)
YIM_RS00165	COG3795	YCII-related domain
YIM_RS00170	COG2815	serine threonine protein kinase
YIM_RS00170	COG0515	serine threonine protein kinase
YIM_RS00175	COG0515	serine threonine protein kinase
YIM_RS00180	COG0768	penicillin binding
YIM_RS00195	COG1716	ATPase activity
YIM_RS00200	COG1716	ATPase activity
YIM_RS00270	COG2186	Transcriptional regulator
YIM_RS00275	COG0747	negative chemotaxis
YIM_RS00285	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YIM_RS00295	COG4608	Belongs to the ABC transporter superfamily
YIM_RS00300	COG1012	belongs to the aldehyde dehydrogenase family
YIM_RS00305	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS00310	COG0154	amidase activity
YIM_RS00320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YIM_RS00340	COG2301	Belongs to the HpcH HpaI aldolase family
YIM_RS00365	COG0702	epimerase
YIM_RS00440	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
YIM_RS00445	COG1174	glycine betaine transport
YIM_RS00455	COG1174	glycine betaine transport
YIM_RS00485	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
YIM_RS00490	COG0697	spore germination
YIM_RS00530	COG0477	Major facilitator Superfamily
YIM_RS00540	COG4585	Histidine kinase
YIM_RS00545	COG2197	response regulator
YIM_RS00565	COG0438	transferase activity, transferring glycosyl groups
YIM_RS00610	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
YIM_RS00615	COG2234	aminopeptidase activity
YIM_RS00655	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
YIM_RS00660	COG3275	phosphorelay sensor kinase activity
YIM_RS00685	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
YIM_RS00690	COG3162	membrane
YIM_RS00695	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
YIM_RS00740	COG1191	sigma factor activity
YIM_RS00750	COG1528	Iron-storage protein
YIM_RS00755	COG2235	arginine
YIM_RS00780	COG0592	DNA-directed DNA polymerase activity
YIM_RS00835	COG1271	oxidase subunit
YIM_RS00840	COG1294	oxidase, subunit
YIM_RS00845	COG4988	ABC transporter
YIM_RS00855	COG1335	isochorismatase
YIM_RS00890	COG4715	Zinc finger, swim domain protein
YIM_RS00900	COG1072	(Pantothenic acid kinase))
YIM_RS00905	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
YIM_RS00915	COG0406	alpha-ribazole phosphatase activity
YIM_RS00920	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
YIM_RS00970	COG0754	glutathionylspermidine amidase activity
YIM_RS00975	COG3766	membrane
YIM_RS00980	COG0596	Alpha beta hydrolase
YIM_RS00985	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
YIM_RS01000	COG0579	oxidoreductase
YIM_RS01060	COG0438	transferase activity, transferring glycosyl groups
YIM_RS01065	COG0110	maltose O-acetyltransferase activity
YIM_RS01090	COG0673	inositol 2-dehydrogenase activity
YIM_RS01095	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
YIM_RS01105	COG0546	phosphoglycolate phosphatase activity
YIM_RS01110	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
YIM_RS01120	COG0318	PFAM AMP-dependent synthetase and ligase
YIM_RS01160	COG0561	phosphatase activity
YIM_RS01165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
YIM_RS01180	COG0671	phosphoesterase, PA-phosphatase related
YIM_RS01185	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
YIM_RS01215	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS01220	COG0277	FAD linked oxidase domain protein
YIM_RS01230	COG1216	Glycosyl transferase, family 2
YIM_RS01260	COG1216	Glycosyl transferase, family 2
YIM_RS01290	COG1063	alcohol dehydrogenase
YIM_RS01295	COG2234	aminopeptidase activity
YIM_RS01355	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
YIM_RS01355	COG1672	PFAM Archaeal ATPase
YIM_RS01365	COG1960	acyl-CoA dehydrogenase activity
YIM_RS01380	COG2910	NAD(P)H-binding
YIM_RS01395	COG4585	Histidine kinase
YIM_RS01400	COG2197	response regulator
YIM_RS01405	COG2814	Major facilitator Superfamily
YIM_RS01415	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
YIM_RS01430	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
YIM_RS01440	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
YIM_RS01460	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
YIM_RS01465	COG0412	Dienelactone hydrolase
YIM_RS01485	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
YIM_RS01590	COG0667	Aldo Keto reductase
YIM_RS01595	COG3647	Membrane
YIM_RS01630	COG4585	Histidine kinase
YIM_RS01635	COG2197	response regulator
YIM_RS01645	COG2183	response to ionizing radiation
YIM_RS01660	COG2080	2 iron, 2 sulfur cluster binding
YIM_RS01665	COG1529	Aldehyde oxidase and xanthine dehydrogenase
YIM_RS01665	COG2010	Cytochrome c
YIM_RS01685	COG3559	Exporter of polyketide antibiotics
YIM_RS01690	COG1131	(ABC) transporter
YIM_RS01715	COG0287	Prephenate dehydrogenase
YIM_RS01720	COG1473	amidohydrolase
YIM_RS01745	COG0596	Alpha beta hydrolase
YIM_RS01775	COG1674	ftsk spoiiie
YIM_RS01800	COG2205	protein histidine kinase activity
YIM_RS01805	COG0745	RESPONSE REGULATOR receiver
YIM_RS01830	COG1739	Uncharacterized protein family UPF0029
YIM_RS01860	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
YIM_RS01900	COG2197	response regulator
YIM_RS01910	COG0745	RESPONSE REGULATOR receiver
YIM_RS01915	COG2205	protein histidine kinase activity
YIM_RS01920	COG3540	Alkaline phosphatase
YIM_RS01935	COG3467	pyridoxamine 5'-phosphate
YIM_RS01940	COG1733	regulation of RNA biosynthetic process
YIM_RS01945	COG0860	N-Acetylmuramoyl-L-alanine amidase
YIM_RS01950	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
YIM_RS01955	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
YIM_RS01965	COG0747	negative chemotaxis
YIM_RS01970	COG0601	transmembrane transport
YIM_RS01975	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YIM_RS01985	COG4608	Belongs to the ABC transporter superfamily
YIM_RS01990	COG0702	epimerase
YIM_RS02000	COG0583	DNA-binding transcription factor activity
YIM_RS02010	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS02020	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
YIM_RS02060	COG1690	Belongs to the RtcB family
YIM_RS02090	COG0657	acetylesterase activity
YIM_RS02100	COG1764	response to oxidative stress
YIM_RS02115	COG2226	methyltransferase
YIM_RS02130	COG1408	metallophosphoesterase
YIM_RS02135	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
YIM_RS02160	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
YIM_RS02215	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
YIM_RS02230	COG0596	Alpha beta hydrolase
YIM_RS02240	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
YIM_RS02245	COG3104	oligopeptide transport
YIM_RS02290	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
YIM_RS02300	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
YIM_RS02310	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
YIM_RS02315	COG1737	Transcriptional regulator
YIM_RS02320	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
YIM_RS02325	COG3876	Protein conserved in bacteria
YIM_RS02330	COG1472	Belongs to the glycosyl hydrolase 3 family
YIM_RS02380	COG1111	helicase
YIM_RS02380	COG1205	dead DEAH box helicase
YIM_RS02385	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
YIM_RS02410	COG1754	DNA topoisomerase type I activity
YIM_RS02410	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
YIM_RS02425	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
YIM_RS02460	COG1674	ftsk spoiiie
YIM_RS02510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YIM_RS02525	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
YIM_RS02540	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
YIM_RS02550	COG0640	Transcriptional regulator
YIM_RS02565	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
YIM_RS02570	COG2027	D-alanyl-D-alanine carboxypeptidase
YIM_RS02580	COG0037	tRNA processing
YIM_RS02610	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
YIM_RS02620	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
YIM_RS02635	COG0789	Transcriptional regulator
YIM_RS02660	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
YIM_RS02665	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
YIM_RS02670	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
YIM_RS02730	COG0596	Alpha beta hydrolase
YIM_RS02740	COG1194	a g-specific adenine glycosylase
YIM_RS02750	COG1609	Transcriptional regulator
YIM_RS02760	COG1120	ATPase activity
YIM_RS02775	COG4399	Belongs to the UPF0754 family
YIM_RS02815	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YIM_RS02820	COG0215	cysteine-tRNA ligase activity
YIM_RS02830	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
YIM_RS02835	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
YIM_RS02840	COG1329	Transcriptional regulator
YIM_RS02845	COG2847	Copper chaperone PCu(A)C
YIM_RS02850	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
YIM_RS02885	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
YIM_RS02895	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
YIM_RS02915	COG0384	phenazine biosynthesis protein PhzF
YIM_RS02920	COG0583	DNA-binding transcription factor activity
YIM_RS02925	COG1695	Transcriptional regulator
YIM_RS02930	COG0446	pyridine nucleotide-disulphide oxidoreductase
YIM_RS02930	COG1902	pentaerythritol trinitrate reductase activity
YIM_RS02950	COG2197	response regulator
YIM_RS02980	COG1832	CoA-binding protein
YIM_RS03000	COG1309	transcriptional regulator
YIM_RS03015	COG1250	3-hydroxyacyl-CoA dehydrogenase
YIM_RS03020	COG2124	cytochrome p450
YIM_RS03025	COG1012	belongs to the aldehyde dehydrogenase family
YIM_RS03025	COG2030	dehydratase
YIM_RS03030	COG3396	Phenylacetate-CoA oxygenase
YIM_RS03035	COG3460	Phenylacetate-CoA oxygenase
YIM_RS03040	COG3396	Phenylacetate-CoA oxygenase
YIM_RS03045	COG2151	metal-sulfur cluster biosynthetic enzyme
YIM_RS03050	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YIM_RS03055	COG0477	Major facilitator Superfamily
YIM_RS03075	COG0129	dihydroxy-acid dehydratase activity
YIM_RS03110	COG0346	lactoylglutathione lyase activity
YIM_RS03115	COG0400	carboxylic ester hydrolase activity
YIM_RS03125	COG4399	Belongs to the UPF0754 family
YIM_RS03135	COG0456	acetyltransferase
YIM_RS03145	COG1917	Cupin 2, conserved barrel domain protein
YIM_RS03150	COG5285	phytanoyl-CoA dioxygenase
YIM_RS03155	COG3629	intracellular signal transduction
YIM_RS03155	COG3903	Transcriptional regulator
YIM_RS03175	COG2885	chlorophyll binding
YIM_RS03195	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
YIM_RS03205	COG2971	BadF BadG BcrA BcrD
YIM_RS03210	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
YIM_RS03215	COG2188	Transcriptional regulator
YIM_RS03220	COG0477	Major facilitator Superfamily
YIM_RS03235	COG0537	adenosine 5'-monophosphoramidase activity
YIM_RS03240	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
YIM_RS03260	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
YIM_RS03265	COG0352	thiamine-phosphate diphosphorylase activity
YIM_RS03270	COG2022	thiamine diphosphate biosynthetic process
YIM_RS03270	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
YIM_RS03280	COG2022	thiamine diphosphate biosynthetic process
YIM_RS03310	COG0351	phosphomethylpyrimidine kinase
YIM_RS03315	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
YIM_RS03330	COG0242	peptide deformylase activity
YIM_RS03350	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
YIM_RS03360	COG0688	phosphatidylethanolamine metabolic process
YIM_RS03380	COG1278	Cold shock
YIM_RS03390	COG0459	protein refolding
YIM_RS03405	COG4948	Mandelate Racemase Muconate Lactonizing
YIM_RS03410	COG3629	intracellular signal transduction
YIM_RS03410	COG3903	Transcriptional regulator
YIM_RS03420	COG1414	Transcriptional regulator
YIM_RS03430	COG1061	Type III restriction enzyme res subunit
YIM_RS03455	COG2814	Major facilitator Superfamily
YIM_RS03460	COG0765	amino acid transport
YIM_RS03465	COG0765	amino acid transport
YIM_RS03480	COG2018	Roadblock/LC7 domain
YIM_RS03495	COG2018	Roadblock/LC7 domain
YIM_RS03530	COG1388	LysM domain
YIM_RS03545	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
YIM_RS03565	COG2175	clavaminate synthase activity
YIM_RS03580	COG3304	Inner membrane component domain
YIM_RS03585	COG0384	phenazine biosynthesis protein PhzF
YIM_RS03590	COG0318	PFAM AMP-dependent synthetase and ligase
YIM_RS03595	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
YIM_RS03615	COG1278	Cold shock
YIM_RS03625	COG2814	Major facilitator Superfamily
YIM_RS03650	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YIM_RS03665	COG2252	PERMEase
YIM_RS03675	COG2814	Major facilitator Superfamily
YIM_RS03685	COG2162	N-hydroxyarylamine O-acetyltransferase activity
YIM_RS03695	COG5398	heme oxygenase
YIM_RS03710	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YIM_RS03735	COG2205	protein histidine kinase activity
YIM_RS03740	COG0745	RESPONSE REGULATOR receiver
YIM_RS03755	COG1136	(ABC) transporter
YIM_RS03755	COG0577	efflux transmembrane transporter activity
YIM_RS03760	COG0577	efflux transmembrane transporter activity
YIM_RS03760	COG1136	(ABC) transporter
YIM_RS03765	COG5650	phosphatidylinositol metabolic process
YIM_RS03780	COG2197	response regulator
YIM_RS03815	COG1309	transcriptional regulator
YIM_RS03825	COG0831	urea catabolic process
YIM_RS03830	COG0832	Belongs to the urease beta subunit family
YIM_RS03835	COG0804	urea catabolic process
YIM_RS03845	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
YIM_RS03850	COG0829	nickel cation binding
YIM_RS03870	COG0259	pyridoxamine-phosphate oxidase activity
YIM_RS03890	COG2017	converts alpha-aldose to the beta-anomer
YIM_RS03895	COG1228	amidohydrolase
YIM_RS03900	COG1960	acyl-CoA dehydrogenase activity
YIM_RS03910	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YIM_RS03920	COG0415	Belongs to the DNA photolyase family
YIM_RS03925	COG1668	transmembrane transport
YIM_RS03930	COG4152	abc transporter atp-binding protein
YIM_RS03955	COG0277	FAD linked oxidase domain protein
YIM_RS04000	COG1169	isochorismate synthase
YIM_RS04025	COG1301	dicarboxylic acid transport
YIM_RS04030	COG1960	acyl-CoA dehydrogenase activity
YIM_RS04050	COG0318	PFAM AMP-dependent synthetase and ligase
YIM_RS04055	COG1024	Enoyl-CoA hydratase
YIM_RS04070	COG1321	iron dependent repressor
YIM_RS04080	COG1113	amino acid transport
YIM_RS04105	COG2409	Drug exporters of the RND superfamily
YIM_RS04115	COG0745	RESPONSE REGULATOR receiver
YIM_RS04125	COG4221	oxidoreductase activity
YIM_RS04135	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YIM_RS04155	COG1335	isochorismatase
YIM_RS04200	COG0596	Alpha beta hydrolase
YIM_RS04215	COG2205	protein histidine kinase activity
YIM_RS04220	COG0745	RESPONSE REGULATOR receiver
YIM_RS04235	COG1136	(ABC) transporter
YIM_RS04240	COG0577	efflux transmembrane transporter activity
YIM_RS04240	COG1136	(ABC) transporter
YIM_RS04280	COG0596	Alpha beta hydrolase
YIM_RS04330	COG2197	response regulator
YIM_RS04335	COG2860	membrane
YIM_RS04350	COG1349	DNA-binding transcription factor activity
YIM_RS04360	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YIM_RS04395	COG0745	RESPONSE REGULATOR receiver
YIM_RS04400	COG5002	protein histidine kinase activity
YIM_RS04410	COG0315	cyclic pyranopterin monophosphate synthase activity
YIM_RS04410	COG0521	Mo-molybdopterin cofactor biosynthetic process
YIM_RS04415	COG1970	mechanosensitive ion channel activity
YIM_RS04430	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
YIM_RS04435	COG1210	Utp--glucose-1-phosphate uridylyltransferase
YIM_RS04465	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
YIM_RS04490	COG2910	NAD(P)H-binding
YIM_RS04495	COG1309	transcriptional regulator
YIM_RS04505	COG4585	Histidine kinase
YIM_RS04510	COG2197	response regulator
YIM_RS04515	COG2409	Drug exporters of the RND superfamily
YIM_RS04540	COG1012	belongs to the aldehyde dehydrogenase family
YIM_RS04550	COG2258	MOSC domain
YIM_RS04635	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
YIM_RS04640	COG0084	hydrolase, TatD family'
YIM_RS04645	COG3583	domain protein
YIM_RS04655	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
YIM_RS04660	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
YIM_RS04665	COG0488	(ABC) transporter
YIM_RS04670	COG0318	PFAM AMP-dependent synthetase and ligase
YIM_RS04685	COG0193	aminoacyl-tRNA hydrolase activity
YIM_RS04700	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
YIM_RS04710	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
YIM_RS04730	COG1309	transcriptional regulator
YIM_RS04745	COG2133	pyrroloquinoline quinone binding
YIM_RS04780	COG3634	alkyl hydroperoxide reductase activity
YIM_RS04800	COG0148	phosphopyruvate hydratase activity
YIM_RS04830	COG0747	negative chemotaxis
YIM_RS04835	COG0601	transmembrane transport
YIM_RS04840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YIM_RS04845	COG0444	Belongs to the ABC transporter superfamily
YIM_RS04850	COG4608	Belongs to the ABC transporter superfamily
YIM_RS04855	COG1404	Belongs to the peptidase S8 family
YIM_RS04890	COG1252	NADH dehydrogenase
YIM_RS04905	COG2197	response regulator
YIM_RS04910	COG4585	Histidine kinase
YIM_RS04920	COG1733	regulation of RNA biosynthetic process
YIM_RS04945	COG1953	Uracil, thiamine, allantoin
YIM_RS04950	COG1802	Transcriptional regulator
YIM_RS04960	COG0789	Transcriptional regulator
YIM_RS04965	COG1902	pentaerythritol trinitrate reductase activity
YIM_RS04985	COG2391	methyltransferase activity
YIM_RS04990	COG0183	Belongs to the thiolase family
YIM_RS05030	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
YIM_RS05035	COG3185	4-Hydroxyphenylpyruvate dioxygenase
YIM_RS05045	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YIM_RS05050	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YIM_RS05060	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
YIM_RS05070	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
YIM_RS05080	COG1331	Highly conserved protein containing a thioredoxin domain
YIM_RS05100	COG0789	Transcriptional regulator
YIM_RS05125	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
YIM_RS05175	COG1793	dna ligase
YIM_RS05180	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
YIM_RS05185	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YIM_RS05195	COG0667	Aldo Keto reductase
YIM_RS05215	COG0114	fumarate hydratase activity
YIM_RS05220	COG0492	ferredoxin-NADP+ reductase activity
YIM_RS05235	COG1722	exodeoxyribonuclease VII activity
YIM_RS05245	COG1570	exodeoxyribonuclease VII activity
YIM_RS05255	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
YIM_RS05260	COG0667	Aldo Keto reductase
YIM_RS05275	COG0420	3'-5' exonuclease activity
YIM_RS05280	COG0419	ATPase involved in DNA repair
YIM_RS05290	COG0012	GTP binding
YIM_RS05305	COG2154	pterin-4-alpha-carbinolamine dehydratase
YIM_RS05320	COG3842	ATPase activity
YIM_RS05330	COG1131	(ABC) transporter
YIM_RS05340	COG0745	RESPONSE REGULATOR receiver
YIM_RS05350	COG0494	nUDIX hydrolase
YIM_RS05355	COG0180	Tryptophanyl-tRNA synthetase
YIM_RS05365	COG1217	gtp-binding protein TYPA
YIM_RS05370	COG0747	negative chemotaxis
YIM_RS05400	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
YIM_RS05415	COG1994	Peptidase M50
YIM_RS05445	COG2835	tetraacyldisaccharide 4'-kinase activity
YIM_RS05455	COG1482	cell wall glycoprotein biosynthetic process
YIM_RS05480	COG0531	amino acid
YIM_RS05490	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
YIM_RS05500	COG1414	Transcriptional regulator
YIM_RS05505	COG0745	RESPONSE REGULATOR receiver
YIM_RS05510	COG5002	protein histidine kinase activity
YIM_RS05515	COG5401	PFAM Sporulation and spore germination
YIM_RS05525	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
YIM_RS05530	COG0653	protein targeting
YIM_RS05540	COG1011	Hydrolase
YIM_RS05545	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YIM_RS05560	COG1012	belongs to the aldehyde dehydrogenase family
YIM_RS05570	COG1162	GTPase activity
YIM_RS05575	COG2135	peptidase activity
YIM_RS05585	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
YIM_RS05590	COG1595	DNA-templated transcription, initiation
YIM_RS05600	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
YIM_RS05615	COG1597	lipid kinase activity
YIM_RS05630	COG0406	alpha-ribazole phosphatase activity
YIM_RS05645	COG0281	malic enzyme
YIM_RS05655	COG1125	glycine betaine transport
YIM_RS05655	COG0517	IMP dehydrogenase activity
YIM_RS05660	COG1174	glycine betaine transport
YIM_RS05665	COG1174	glycine betaine transport
YIM_RS05675	COG3153	acetyltransferase
YIM_RS05685	COG0508	dehydrogenase complex catalyzes the overall conversion of
YIM_RS05685	COG0567	Dehydrogenase, E1 component
YIM_RS05725	COG1132	(ABC) transporter
YIM_RS05740	COG0477	Major facilitator Superfamily
YIM_RS05750	COG0686	Belongs to the AlaDH PNT family
YIM_RS05770	COG2508	Transcriptional regulator
YIM_RS05770	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
YIM_RS05785	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
YIM_RS05820	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
YIM_RS05830	COG1960	acyl-CoA dehydrogenase activity
YIM_RS05840	COG4221	oxidoreductase activity
YIM_RS05855	COG1434	Gram-negative-bacterium-type cell wall biogenesis
YIM_RS05870	COG1960	acyl-CoA dehydrogenase activity
YIM_RS05880	COG1309	transcriptional regulator
YIM_RS05885	COG0183	Belongs to the thiolase family
YIM_RS05890	COG1250	3-hydroxyacyl-CoA dehydrogenase
YIM_RS05890	COG1024	Enoyl-CoA hydratase
YIM_RS05915	COG0028	Belongs to the TPP enzyme family
YIM_RS05930	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
YIM_RS05940	COG0473	3-isopropylmalate dehydrogenase activity
YIM_RS05945	COG0815	Transfers the fatty acyl group on membrane lipoproteins
YIM_RS05950	COG2186	Transcriptional regulator
YIM_RS05970	COG0154	amidase activity
YIM_RS05985	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
YIM_RS06000	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
YIM_RS06015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
YIM_RS06035	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS06055	COG1804	L-carnitine dehydratase bile acid-inducible protein F
YIM_RS06090	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
YIM_RS06100	COG0640	Transcriptional regulator
YIM_RS06105	COG2267	carboxylic ester hydrolase activity
YIM_RS06110	COG0702	epimerase
YIM_RS06120	COG3250	beta-galactosidase activity
YIM_RS06125	COG1129	ABC transporter
YIM_RS06130	COG1172	Belongs to the binding-protein-dependent transport system permease family
YIM_RS06140	COG1879	ABC-type sugar transport system periplasmic component
YIM_RS06145	COG4952	isomerase
YIM_RS06160	COG1879	ABC-type sugar transport system periplasmic component
YIM_RS06165	COG1129	ABC transporter
YIM_RS06170	COG1172	Belongs to the binding-protein-dependent transport system permease family
YIM_RS06175	COG1172	Belongs to the binding-protein-dependent transport system permease family
YIM_RS06190	COG1280	lysine exporter protein (LysE YggA)
YIM_RS06195	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
YIM_RS06195	COG0072	phenylalanine-tRNA ligase activity
YIM_RS06205	COG4941	Belongs to the sigma-70 factor family
YIM_RS06210	COG0129	dihydroxy-acid dehydratase activity
YIM_RS06230	COG0018	arginyl-trna synthetase
YIM_RS06235	COG0019	diaminopimelate decarboxylase activity
YIM_RS06245	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
YIM_RS06250	COG0083	homoserine kinase activity
YIM_RS06255	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
YIM_RS06265	COG0254	rRNA binding
YIM_RS06270	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
YIM_RS06280	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
YIM_RS06290	COG0789	Transcriptional regulator
YIM_RS06295	COG2890	protein-(glutamine-N5) methyltransferase activity
YIM_RS06305	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
YIM_RS06330	COG0356	it plays a direct role in the translocation of protons across the membrane
YIM_RS06335	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
YIM_RS06340	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
YIM_RS06345	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
YIM_RS06355	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
YIM_RS06360	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
YIM_RS06365	COG0355	proton-transporting ATP synthase activity, rotational mechanism
YIM_RS06395	COG1280	lysine exporter protein (LysE YggA)
YIM_RS06400	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
YIM_RS06400	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
YIM_RS06405	COG1674	ftsk spoiiie
YIM_RS06410	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
YIM_RS06425	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
YIM_RS06445	COG2376	Dihydroxyacetone kinase
YIM_RS06450	COG1461	Dihydroxyacetone kinase
YIM_RS06455	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
YIM_RS06455	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
YIM_RS06465	COG1250	3-hydroxyacyl-CoA dehydrogenase
YIM_RS06485	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
YIM_RS06490	COG2207	Transcriptional regulator
YIM_RS06505	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YIM_RS06515	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
YIM_RS06515	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YIM_RS06530	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
YIM_RS06530	COG1672	PFAM Archaeal ATPase
YIM_RS06540	COG0653	protein targeting
YIM_RS06570	COG0174	glutamine synthetase
YIM_RS06605	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
YIM_RS06665	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
YIM_RS06685	COG3480	Lon protease (S16) C-terminal proteolytic domain
YIM_RS06695	COG1615	UPF0182 protein
YIM_RS06705	COG2378	regulation of single-species biofilm formation
YIM_RS06725	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
YIM_RS06730	COG2884	Cell division ATP-binding protein ftsE
YIM_RS06735	COG2177	Part of the ABC transporter FtsEX involved in
YIM_RS06740	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
YIM_RS06760	COG1846	Transcriptional regulator
YIM_RS06770	COG2197	response regulator
YIM_RS06775	COG4585	Histidine kinase
YIM_RS06825	COG1937	Protein conserved in bacteria
YIM_RS06850	COG2986	histidine ammonia-lyase
YIM_RS06855	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
YIM_RS06870	COG1228	amidohydrolase
YIM_RS06890	COG1819	glycosyl
YIM_RS06895	COG4585	Histidine kinase
YIM_RS06920	COG0671	phosphoesterase, PA-phosphatase related
YIM_RS06935	COG1643	Atp-dependent helicase
YIM_RS06940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YIM_RS06955	COG0791	NLP P60 protein
YIM_RS06955	COG3883	PFAM NLP P60 protein
YIM_RS06995	COG1819	glycosyl
YIM_RS07000	COG3629	intracellular signal transduction
YIM_RS07000	COG3903	Transcriptional regulator
YIM_RS07050	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YIM_RS07050	COG3153	acetyltransferase
YIM_RS07055	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
YIM_RS07085	COG1366	Belongs to the anti-sigma-factor antagonist family
YIM_RS07090	COG1366	Belongs to the anti-sigma-factor antagonist family
YIM_RS07095	COG2172	sigma factor antagonist activity
YIM_RS07230	COG1309	transcriptional regulator
YIM_RS07245	COG2267	carboxylic ester hydrolase activity
YIM_RS07330	COG0667	Aldo Keto reductase
YIM_RS07395	COG1011	Hydrolase
YIM_RS07465	COG3706	GGDEF domain
YIM_RS07570	COG0714	Associated with various cellular activities
YIM_RS07665	COG4974	Belongs to the 'phage' integrase family
YIM_RS07695	COG3103	Sh3 type 3 domain protein
YIM_RS07695	COG1388	LysM domain
YIM_RS07695	COG0791	NLP P60 protein
YIM_RS07765	COG0270	DNA (cytosine-5-)-methyltransferase activity
YIM_RS07855	COG3903	Transcriptional regulator
YIM_RS07855	COG3629	intracellular signal transduction
YIM_RS07885	COG0583	DNA-binding transcription factor activity
YIM_RS07890	COG0076	glutamate decarboxylase activity
YIM_RS07900	COG1162	GTPase activity
YIM_RS07940	COG1053	succinate dehydrogenase
YIM_RS08010	COG0738	Major facilitator superfamily
YIM_RS08025	COG0789	Transcriptional regulator
YIM_RS08030	COG2362	D-Aminopeptidase
YIM_RS08045	COG1733	regulation of RNA biosynthetic process
YIM_RS08050	COG0702	epimerase
YIM_RS08055	COG2311	Membrane
YIM_RS08060	COG4585	Histidine kinase
YIM_RS08065	COG2197	response regulator
YIM_RS08085	COG2318	DinB family
YIM_RS08115	COG0596	Alpha beta hydrolase
YIM_RS08175	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
YIM_RS08220	COG2226	methyltransferase
YIM_RS08240	COG3226	Transcriptional regulator
YIM_RS08245	COG3903	Transcriptional regulator
YIM_RS08245	COG3629	intracellular signal transduction
YIM_RS08250	COG2610	gluconate transmembrane transporter activity
YIM_RS08265	COG0583	DNA-binding transcription factor activity
YIM_RS08285	COG1309	transcriptional regulator
YIM_RS08295	COG4977	sequence-specific DNA binding
YIM_RS08320	COG2205	protein histidine kinase activity
YIM_RS08325	COG0745	RESPONSE REGULATOR receiver
YIM_RS08340	COG1131	(ABC) transporter
YIM_RS08355	COG0017	Asparaginyl-tRNA synthetase
YIM_RS08375	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
YIM_RS08430	COG1316	TRANSCRIPTIONal
YIM_RS08445	COG3903	Transcriptional regulator
YIM_RS08445	COG3629	intracellular signal transduction
YIM_RS08460	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS08470	COG1309	transcriptional regulator
YIM_RS08490	COG1116	anion transmembrane transporter activity
YIM_RS08495	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YIM_RS08505	COG2018	Roadblock/LC7 domain
YIM_RS08520	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
YIM_RS08525	COG1595	DNA-templated transcription, initiation
YIM_RS08530	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
YIM_RS08570	COG2205	protein histidine kinase activity
YIM_RS08575	COG2018	Roadblock/LC7 domain
YIM_RS08615	COG0387	Pfam Sodium calcium exchanger
YIM_RS08620	COG0318	PFAM AMP-dependent synthetase and ligase
YIM_RS08625	COG0385	Bile acid
YIM_RS08635	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
YIM_RS08640	COG1846	Transcriptional regulator
YIM_RS08645	COG0446	pyridine nucleotide-disulphide oxidoreductase
YIM_RS08655	COG1121	(ABC) transporter
YIM_RS08710	COG0531	amino acid
YIM_RS08720	COG2197	response regulator
YIM_RS08725	COG3903	Transcriptional regulator
YIM_RS08725	COG3629	intracellular signal transduction
YIM_RS08750	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
YIM_RS08755	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
YIM_RS08765	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
YIM_RS08785	COG0297	glycogen (starch) synthase activity
YIM_RS08795	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
YIM_RS08800	COG0483	inositol monophosphate 1-phosphatase activity
YIM_RS08830	COG1846	Transcriptional regulator
YIM_RS08835	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS08900	COG1434	Gram-negative-bacterium-type cell wall biogenesis
YIM_RS08930	COG1376	ErfK ybiS ycfS ynhG family protein
YIM_RS08940	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
YIM_RS08945	COG0433	COG0433 Predicted ATPase
YIM_RS08960	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YIM_RS08970	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
YIM_RS08975	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
YIM_RS08980	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
YIM_RS08990	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
YIM_RS09000	COG1418	mRNA catabolic process
YIM_RS09015	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
YIM_RS09045	COG0346	lactoylglutathione lyase activity
YIM_RS09050	COG0183	Belongs to the thiolase family
YIM_RS09070	COG1309	transcriptional regulator
YIM_RS09075	COG0300	oxidoreductase activity
YIM_RS09080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YIM_RS09085	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YIM_RS09090	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
YIM_RS09100	COG1172	Belongs to the binding-protein-dependent transport system permease family
YIM_RS09115	COG1609	Transcriptional regulator
YIM_RS09120	COG2409	Drug exporters of the RND superfamily
YIM_RS09125	COG1846	Transcriptional regulator
YIM_RS09150	COG0058	SHG alpha-glucan phosphorylase activity
YIM_RS09175	COG1119	ATPase activity
YIM_RS09195	COG2197	response regulator
YIM_RS09200	COG4585	Histidine kinase
YIM_RS09225	COG4195	phage-related replication protein
YIM_RS09235	COG0789	Transcriptional regulator
YIM_RS09240	COG0346	lactoylglutathione lyase activity
YIM_RS09270	COG2267	carboxylic ester hydrolase activity
YIM_RS09275	COG0110	maltose O-acetyltransferase activity
YIM_RS09285	COG0640	Transcriptional regulator
YIM_RS09295	COG2814	Major facilitator Superfamily
YIM_RS09305	COG0604	alcohol dehydrogenase
YIM_RS09320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YIM_RS09340	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YIM_RS09375	COG4221	oxidoreductase activity
YIM_RS09385	COG0446	pyridine nucleotide-disulphide oxidoreductase
YIM_RS09385	COG1902	pentaerythritol trinitrate reductase activity
YIM_RS09390	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS09395	COG3103	Sh3 type 3 domain protein
YIM_RS09395	COG1388	LysM domain
YIM_RS09395	COG0791	NLP P60 protein
YIM_RS09405	COG0110	maltose O-acetyltransferase activity
YIM_RS09430	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
YIM_RS09475	COG0386	Belongs to the glutathione peroxidase family
YIM_RS09485	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
YIM_RS09495	COG1307	EDD domain protein, DegV family
YIM_RS09505	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
YIM_RS09520	COG0477	Major facilitator Superfamily
YIM_RS09530	COG0482	sulfurtransferase activity
YIM_RS09545	COG3386	PFAM SMP-30 Gluconolaconase
YIM_RS09550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YIM_RS09560	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
YIM_RS09560	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YIM_RS09575	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
YIM_RS09580	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
YIM_RS09590	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
YIM_RS09595	COG0154	amidase activity
YIM_RS09605	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
YIM_RS09635	COG0129	dihydroxy-acid dehydratase activity
YIM_RS09650	COG0440	acetolactate synthase activity
YIM_RS09655	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
YIM_RS09695	COG1404	Belongs to the peptidase S8 family
YIM_RS09700	COG0473	3-isopropylmalate dehydrogenase activity
YIM_RS09705	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
YIM_RS09710	COG0179	Fumarylacetoacetate (FAA) hydrolase
YIM_RS09720	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
YIM_RS09755	COG1309	transcriptional regulator
YIM_RS09775	COG0463	Glycosyl transferase, family 2
YIM_RS09790	COG0640	Transcriptional regulator
YIM_RS09795	COG0492	ferredoxin-NADP+ reductase activity
YIM_RS09805	COG2072	flavoprotein involved in K transport
YIM_RS09835	COG0346	lactoylglutathione lyase activity
YIM_RS09845	COG0640	Transcriptional regulator
YIM_RS09880	COG1131	(ABC) transporter
YIM_RS09920	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YIM_RS09935	COG4221	oxidoreductase activity
YIM_RS09945	COG2132	Multicopper oxidase
YIM_RS10000	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
YIM_RS10070	COG2409	Drug exporters of the RND superfamily
YIM_RS10105	COG2205	protein histidine kinase activity
YIM_RS10115	COG0183	Belongs to the thiolase family
YIM_RS10125	COG2030	dehydratase
YIM_RS10130	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS10140	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
YIM_RS10145	COG0066	3-isopropylmalate dehydratase activity
YIM_RS10155	COG3903	Transcriptional regulator
YIM_RS10155	COG3629	intracellular signal transduction
YIM_RS10170	COG1920	GTP binding
YIM_RS10180	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
YIM_RS10195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YIM_RS10200	COG1181	Belongs to the D-alanine--D-alanine ligase family
YIM_RS10235	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
YIM_RS10240	COG0227	Belongs to the bacterial ribosomal protein bL28 family
YIM_RS10245	COG1461	Dihydroxyacetone kinase
YIM_RS10265	COG4191	Histidine kinase
YIM_RS10285	COG2814	Major facilitator Superfamily
YIM_RS10290	COG4336	lyase activity
YIM_RS10295	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
YIM_RS10300	COG1984	allophanate hydrolase subunit 2
YIM_RS10340	COG1929	Belongs to the glycerate kinase type-1 family
YIM_RS10355	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
YIM_RS10360	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
YIM_RS10370	COG3485	protocatechuate 3,4-dioxygenase
YIM_RS10375	COG3485	protocatechuate 3,4-dioxygenase
YIM_RS10380	COG0596	Alpha beta hydrolase
YIM_RS10385	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YIM_RS10390	COG1414	Transcriptional regulator
YIM_RS10395	COG0746	molybdenum cofactor guanylyltransferase activity
YIM_RS10400	COG1349	DNA-binding transcription factor activity
YIM_RS10405	COG1105	Belongs to the carbohydrate kinase PfkB family
YIM_RS10415	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
YIM_RS10415	COG2213	PTS system mannitol-specific
YIM_RS10420	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
YIM_RS10420	COG2213	PTS system mannitol-specific
YIM_RS10425	COG1063	alcohol dehydrogenase
YIM_RS10430	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
YIM_RS10435	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
YIM_RS10440	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
YIM_RS10480	COG3795	YCII-related domain
YIM_RS10485	COG5650	phosphatidylinositol metabolic process
YIM_RS10490	COG3962	Belongs to the TPP enzyme family
YIM_RS10495	COG3718	enzyme involved in inositol metabolism
YIM_RS10505	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YIM_RS10525	COG1082	Xylose isomerase domain protein TIM barrel
YIM_RS10530	COG1609	Transcriptional regulator
YIM_RS10535	COG0673	inositol 2-dehydrogenase activity
YIM_RS10550	COG0531	amino acid
YIM_RS10560	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
YIM_RS10565	COG1012	belongs to the aldehyde dehydrogenase family
YIM_RS10575	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
YIM_RS10575	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
YIM_RS10580	COG0404	The glycine cleavage system catalyzes the degradation of glycine
YIM_RS10585	COG0509	glycine decarboxylation via glycine cleavage system
YIM_RS10590	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
YIM_RS10595	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
YIM_RS10600	COG1760	l-serine dehydratase
YIM_RS10605	COG2186	Transcriptional regulator
YIM_RS10610	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
YIM_RS10615	COG4122	O-methyltransferase activity
YIM_RS10620	COG1120	ATPase activity
YIM_RS10625	COG4221	oxidoreductase activity
YIM_RS10645	COG2910	NAD(P)H-binding
YIM_RS10650	COG2814	Major facilitator Superfamily
YIM_RS10660	COG0475	glutathione-regulated potassium exporter activity
YIM_RS10675	COG1643	Atp-dependent helicase
YIM_RS10700	COG0318	PFAM AMP-dependent synthetase and ligase
YIM_RS10740	COG4948	Mandelate Racemase Muconate Lactonizing
YIM_RS10750	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YIM_RS10760	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
YIM_RS10760	COG1116	anion transmembrane transporter activity
YIM_RS10765	COG0673	inositol 2-dehydrogenase activity
YIM_RS10810	COG4948	Mandelate Racemase Muconate Lactonizing
YIM_RS10830	COG0542	response to heat
YIM_RS10840	COG1228	amidohydrolase
YIM_RS10855	COG3275	phosphorelay sensor kinase activity
YIM_RS10860	COG3279	Response regulator of the LytR AlgR family
YIM_RS10870	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
YIM_RS10880	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
YIM_RS10885	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
YIM_RS10935	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
YIM_RS10980	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
YIM_RS10985	COG3973	AAA domain
YIM_RS10990	COG0742	ribosomal rna small subunit methyltransferase
YIM_RS10995	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
YIM_RS11015	COG0333	Belongs to the bacterial ribosomal protein bL32 family
YIM_RS11020	COG0571	ribonuclease III activity
YIM_RS11025	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
YIM_RS11045	COG1940	carbohydrate kinase activity
YIM_RS11050	COG0367	asparagine synthase
YIM_RS11060	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
YIM_RS11070	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
YIM_RS11090	COG1254	Belongs to the acylphosphatase family
YIM_RS11125	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
YIM_RS11130	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
YIM_RS11140	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YIM_RS11145	COG1414	Transcriptional regulator
YIM_RS11150	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
YIM_RS11160	COG1301	dicarboxylic acid transport
YIM_RS11165	COG3835	regulator
YIM_RS11185	COG1529	Aldehyde oxidase and xanthine dehydrogenase
YIM_RS11195	COG1309	transcriptional regulator
YIM_RS11200	COG2233	PERMEase
YIM_RS11230	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
YIM_RS11235	COG1832	CoA-binding protein
YIM_RS11240	COG2873	o-acetylhomoserine
YIM_RS11245	COG0667	Aldo Keto reductase
YIM_RS11275	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
YIM_RS11285	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
YIM_RS11310	COG0228	four-way junction DNA binding
YIM_RS11325	COG0336	Belongs to the RNA methyltransferase TrmD family
YIM_RS11330	COG0335	large ribosomal subunit rRNA binding
YIM_RS11335	COG0681	Belongs to the peptidase S26 family
YIM_RS11340	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
YIM_RS11350	COG0792	nuclease activity
YIM_RS11375	COG1191	sigma factor activity
YIM_RS11385	COG0052	Belongs to the universal ribosomal protein uS2 family
YIM_RS11390	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
YIM_RS11395	COG0528	UMP kinase activity
YIM_RS11400	COG0233	cytoplasmic translational termination
YIM_RS11420	COG1695	Transcriptional regulator
YIM_RS11425	COG0820	rRNA (adenine-C2-)-methyltransferase activity
YIM_RS11455	COG0477	Major facilitator Superfamily
YIM_RS11470	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
YIM_RS11475	COG0019	diaminopimelate decarboxylase activity
YIM_RS11490	COG0604	alcohol dehydrogenase
YIM_RS11490	COG3321	synthase
YIM_RS11510	COG0604	alcohol dehydrogenase
YIM_RS11510	COG3321	synthase
YIM_RS11530	COG3321	synthase
YIM_RS11530	COG0604	alcohol dehydrogenase
YIM_RS11540	COG0604	alcohol dehydrogenase
YIM_RS11540	COG3321	synthase
YIM_RS11545	COG2267	carboxylic ester hydrolase activity
YIM_RS11590	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
YIM_RS11645	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
YIM_RS11670	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
YIM_RS11675	COG0750	zinc metalloprotease
YIM_RS11680	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
YIM_RS11695	COG0456	acetyltransferase
YIM_RS11695	COG0454	-acetyltransferase
YIM_RS11715	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS11730	COG2186	Transcriptional regulator
YIM_RS11735	COG2807	transmembrane transport
YIM_RS11770	COG0513	Belongs to the DEAD box helicase family
YIM_RS11785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
YIM_RS11790	COG3022	response to hydroperoxide
YIM_RS11795	COG0456	acetyltransferase
YIM_RS11800	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YIM_RS11810	COG0442	prolyl-tRNA aminoacylation
YIM_RS11830	COG0432	Pfam Uncharacterised protein family UPF0047
YIM_RS11835	COG2197	response regulator
YIM_RS11870	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
YIM_RS11910	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
YIM_RS11915	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
YIM_RS11945	COG0668	transmembrane transport
YIM_RS11950	COG3201	nicotinamide mononucleotide transporter
YIM_RS11955	COG1620	l-lactate permease
YIM_RS11965	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
YIM_RS11985	COG0702	epimerase
YIM_RS12005	COG0596	Alpha beta hydrolase
YIM_RS12020	COG2267	carboxylic ester hydrolase activity
YIM_RS12050	COG1113	amino acid transport
YIM_RS12060	COG0587	DNA-directed DNA polymerase activity
YIM_RS12075	COG1376	ErfK ybiS ycfS ynhG family protein
YIM_RS12095	COG0586	Pfam SNARE associated Golgi protein
YIM_RS12100	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
YIM_RS12125	COG0321	lipoyl(octanoyl) transferase activity
YIM_RS12150	COG0508	dehydrogenase complex catalyzes the overall conversion of
YIM_RS12155	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YIM_RS12170	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
YIM_RS12190	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
YIM_RS12195	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
YIM_RS12200	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
YIM_RS12205	COG0667	Aldo Keto reductase
YIM_RS12225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YIM_RS12235	COG1414	Transcriptional regulator
YIM_RS12245	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YIM_RS12260	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
YIM_RS12270	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
YIM_RS12280	COG1845	cytochrome c oxidase, subunit III
YIM_RS12285	COG2010	Cytochrome c
YIM_RS12295	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
YIM_RS12320	COG1136	(ABC) transporter
YIM_RS12345	COG0438	transferase activity, transferring glycosyl groups
YIM_RS12350	COG1595	DNA-templated transcription, initiation
YIM_RS12360	COG1309	transcriptional regulator
YIM_RS12370	COG2124	cytochrome p450
YIM_RS12375	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
YIM_RS12380	COG0659	secondary active sulfate transmembrane transporter activity
YIM_RS12385	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
YIM_RS12390	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
YIM_RS12400	COG0501	Belongs to the peptidase M48B family
YIM_RS12420	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
YIM_RS12425	COG0157	Belongs to the NadC ModD family
YIM_RS12430	COG1404	Belongs to the peptidase S8 family
YIM_RS12440	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
YIM_RS12440	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
YIM_RS12465	COG1674	ftsk spoiiie
YIM_RS12480	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
YIM_RS12500	COG2197	response regulator
YIM_RS12510	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
YIM_RS12515	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
YIM_RS12520	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
YIM_RS12525	COG0131	Imidazoleglycerol-phosphate dehydratase
YIM_RS12530	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
YIM_RS12545	COG2208	phosphoserine phosphatase activity
YIM_RS12545	COG2770	Histidine kinase
YIM_RS12555	COG3959	Transketolase, thiamine diphosphate binding domain
YIM_RS12560	COG3958	Transketolase
YIM_RS12605	COG0513	Belongs to the DEAD box helicase family
YIM_RS12615	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
YIM_RS12630	COG1960	acyl-CoA dehydrogenase activity
YIM_RS12640	COG2018	Roadblock/LC7 domain
YIM_RS12655	COG1174	glycine betaine transport
YIM_RS12660	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YIM_RS12675	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
YIM_RS12680	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
YIM_RS12695	COG0107	imidazoleglycerol-phosphate synthase activity
YIM_RS12705	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
YIM_RS12720	COG1309	transcriptional regulator
YIM_RS12725	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
YIM_RS12735	COG0134	indole-3-glycerol-phosphate synthase activity
YIM_RS12740	COG0133	tryptophan synthase activity
YIM_RS12745	COG0159	tryptophan synthase activity
YIM_RS12755	COG0601	transmembrane transport
YIM_RS12765	COG1124	(ABC) transporter
YIM_RS12775	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
YIM_RS12810	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
YIM_RS12815	COG0069	glutamate synthase activity
YIM_RS12815	COG0070	glutamate synthase
YIM_RS12815	COG0067	glutamate synthase
YIM_RS12845	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
YIM_RS12865	COG2268	Band 7 protein
YIM_RS12875	COG0515	serine threonine protein kinase
YIM_RS12875	COG2815	serine threonine protein kinase
YIM_RS12890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
YIM_RS12905	COG0142	geranyltranstransferase activity
YIM_RS12935	COG0583	DNA-binding transcription factor activity
YIM_RS12940	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
YIM_RS12985	COG0242	peptide deformylase activity
YIM_RS12990	COG1201	RNA secondary structure unwinding
YIM_RS12995	COG0443	Heat shock 70 kDa protein
YIM_RS13005	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
YIM_RS13010	COG2137	regulation of response to DNA damage stimulus
YIM_RS13020	COG0800	Aldolase
YIM_RS13040	COG1053	succinate dehydrogenase
YIM_RS13050	COG0765	amino acid transport
YIM_RS13055	COG0765	amino acid transport
YIM_RS13060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YIM_RS13065	COG1126	abc transporter atp-binding protein
YIM_RS13075	COG2205	protein histidine kinase activity
YIM_RS13085	COG3609	addiction module antidote protein, CC2985 family
YIM_RS13090	COG2337	Toxic component of a toxin-antitoxin (TA) module
YIM_RS13095	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
YIM_RS13110	COG1196	nuclear chromosome segregation
YIM_RS13120	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
YIM_RS13125	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
YIM_RS13495	COG2814	Major facilitator Superfamily
YIM_RS13505	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
YIM_RS13515	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
YIM_RS13520	COG1388	LysM domain
YIM_RS13525	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
YIM_RS13530	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
YIM_RS13545	COG1090	epimerase
YIM_RS13555	COG0259	pyridoxamine-phosphate oxidase activity
YIM_RS13565	COG4279	zinc finger
YIM_RS13570	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
YIM_RS13575	COG1228	amidohydrolase
YIM_RS13590	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
YIM_RS13600	COG1505	serine-type exopeptidase activity
YIM_RS13605	COG2321	neutral zinc metallopeptidase
YIM_RS13615	COG0596	Alpha beta hydrolase
YIM_RS13640	COG2936	dipeptidyl-peptidase activity
YIM_RS13665	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
YIM_RS13670	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
YIM_RS13685	COG0123	including yeast histone deacetylase and acetoin utilization protein
YIM_RS13705	COG1960	acyl-CoA dehydrogenase activity
YIM_RS13710	COG1960	acyl-CoA dehydrogenase activity
YIM_RS13715	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS13725	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
YIM_RS13730	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
YIM_RS13785	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
YIM_RS13790	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
YIM_RS13800	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
YIM_RS13805	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
YIM_RS13810	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
YIM_RS13820	COG2318	DinB family
YIM_RS13830	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
YIM_RS13855	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
YIM_RS13860	COG1496	oxidoreductase activity
YIM_RS13870	COG1799	cell septum assembly
YIM_RS13895	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
YIM_RS13900	COG0768	penicillin binding
YIM_RS13920	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
YIM_RS13925	COG0156	8-amino-7-oxononanoate synthase activity
YIM_RS13935	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
YIM_RS14005	COG0003	Pfam Anion-transporting ATPase
YIM_RS14015	COG1940	carbohydrate kinase activity
YIM_RS14025	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
YIM_RS14050	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
YIM_RS14090	COG1946	Acyl-CoA thioesterase
YIM_RS14110	COG1672	PFAM Archaeal ATPase
YIM_RS14110	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
YIM_RS14125	COG1012	belongs to the aldehyde dehydrogenase family
YIM_RS14140	COG1960	acyl-CoA dehydrogenase activity
YIM_RS14145	COG1804	L-carnitine dehydratase bile acid-inducible protein F
YIM_RS14160	COG1566	PFAM secretion protein HlyD family protein
YIM_RS14185	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
YIM_RS14190	COG0019	diaminopimelate decarboxylase activity
YIM_RS14195	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
YIM_RS14210	COG2018	Roadblock/LC7 domain
YIM_RS14225	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
YIM_RS14225	COG1703	isobutyryl-CoA mutase activity
YIM_RS14225	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
YIM_RS14250	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
YIM_RS14255	COG1309	transcriptional regulator
YIM_RS14260	COG1960	acyl-CoA dehydrogenase activity
YIM_RS14265	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
YIM_RS14270	COG2249	NAD(P)H dehydrogenase (quinone) activity
YIM_RS14280	COG1960	acyl-CoA dehydrogenase activity
YIM_RS14285	COG1960	acyl-CoA dehydrogenase activity
YIM_RS14305	COG2030	dehydratase
YIM_RS14310	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YIM_RS14325	COG1053	succinate dehydrogenase
YIM_RS14335	COG1960	acyl-CoA dehydrogenase activity
YIM_RS14340	COG2267	carboxylic ester hydrolase activity
YIM_RS14345	COG0346	lactoylglutathione lyase activity
YIM_RS14350	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
YIM_RS14365	COG1024	Enoyl-CoA hydratase
YIM_RS14385	COG0110	maltose O-acetyltransferase activity
YIM_RS14390	COG0596	Alpha beta hydrolase
YIM_RS14400	COG0183	Belongs to the thiolase family
YIM_RS14405	COG2124	cytochrome p450
YIM_RS14410	COG2226	methyltransferase
YIM_RS14435	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
YIM_RS14440	COG1024	Enoyl-CoA hydratase
YIM_RS14450	COG2070	2-Nitropropane dioxygenase
YIM_RS14460	COG2188	Transcriptional regulator
YIM_RS14490	COG1490	D-aminoacyl-tRNA deacylase activity
YIM_RS14495	COG2890	protein-(glutamine-N5) methyltransferase activity
YIM_RS14520	COG2313	pseudouridylate synthase activity
YIM_RS14540	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YIM_RS14555	COG4213	ABC transporter substrate-binding protein
YIM_RS14565	COG4214	carbohydrate transport
YIM_RS14585	COG2197	response regulator
YIM_RS14645	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YIM_RS14650	COG1414	Transcriptional regulator
YIM_RS14655	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
YIM_RS14680	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS14695	COG3345	alpha-galactosidase
YIM_RS14705	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
YIM_RS14730	COG0028	Belongs to the TPP enzyme family
YIM_RS14740	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
YIM_RS14745	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
YIM_RS14780	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
YIM_RS14785	COG0640	Transcriptional regulator
YIM_RS14795	COG1573	uracil-dna glycosylase
YIM_RS14815	COG0714	Associated with various cellular activities
YIM_RS14825	COG3552	Protein containing von Willebrand factor type A (VWA) domain
YIM_RS14865	COG1309	transcriptional regulator
YIM_RS14875	COG2814	Major facilitator Superfamily
YIM_RS14890	COG0725	ABC transporter, periplasmic molybdate-binding protein
YIM_RS14910	COG0702	epimerase
YIM_RS14920	COG1309	transcriptional regulator
YIM_RS14935	COG1695	Transcriptional regulator
YIM_RS14940	COG0577	efflux transmembrane transporter activity
YIM_RS14940	COG1136	(ABC) transporter
YIM_RS14960	COG1131	(ABC) transporter
YIM_RS14970	COG2197	response regulator
YIM_RS14975	COG2409	Drug exporters of the RND superfamily
YIM_RS14990	COG1309	transcriptional regulator
YIM_RS15000	COG2175	clavaminate synthase activity
YIM_RS15025	COG0142	geranyltranstransferase activity
YIM_RS15030	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
YIM_RS15035	COG1819	glycosyl
YIM_RS15090	COG1063	alcohol dehydrogenase
YIM_RS15095	COG0748	coenzyme F420 binding
YIM_RS15105	COG0596	Alpha beta hydrolase
YIM_RS15110	COG3903	Transcriptional regulator
YIM_RS15110	COG3629	intracellular signal transduction
YIM_RS15115	COG0583	DNA-binding transcription factor activity
YIM_RS15140	COG1414	Transcriptional regulator
YIM_RS15155	COG3485	protocatechuate 3,4-dioxygenase
YIM_RS15160	COG4948	Mandelate Racemase Muconate Lactonizing
YIM_RS15165	COG4829	muconolactone delta-isomerase
YIM_RS15215	COG1302	Protein conserved in bacteria
YIM_RS15235	COG2208	phosphoserine phosphatase activity
YIM_RS15240	COG4251	negative regulation of phosphorylation
YIM_RS15245	COG0784	Response regulator, receiver
YIM_RS15285	COG2197	response regulator
YIM_RS15290	COG4585	Histidine kinase
YIM_RS15390	COG2267	carboxylic ester hydrolase activity
YIM_RS15395	COG0673	inositol 2-dehydrogenase activity
YIM_RS15415	COG1733	regulation of RNA biosynthetic process
YIM_RS15465	COG0667	Aldo Keto reductase
YIM_RS15475	COG1609	Transcriptional regulator
YIM_RS15510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YIM_RS15520	COG1120	ATPase activity
YIM_RS15525	COG2080	2 iron, 2 sulfur cluster binding
YIM_RS15530	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
YIM_RS15535	COG1529	Aldehyde oxidase and xanthine dehydrogenase
YIM_RS15540	COG2207	Transcriptional regulator
YIM_RS15545	COG0515	serine threonine protein kinase
YIM_RS15545	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YIM_RS15555	COG1309	transcriptional regulator
YIM_RS15560	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS15575	COG0640	Transcriptional regulator
YIM_RS15590	COG0702	epimerase
YIM_RS15605	COG0604	alcohol dehydrogenase
YIM_RS15620	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
YIM_RS15625	COG0066	3-isopropylmalate dehydratase activity
YIM_RS15630	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
YIM_RS15660	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
YIM_RS15670	COG3209	COG3209 Rhs family protein
YIM_RS15705	COG0477	Major facilitator Superfamily
YIM_RS15715	COG4106	trans-aconitate 2-methyltransferase activity
YIM_RS15720	COG3903	Transcriptional regulator
YIM_RS15720	COG3629	intracellular signal transduction
YIM_RS15725	COG3321	synthase
YIM_RS15725	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
YIM_RS15735	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YIM_RS15745	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
YIM_RS15775	COG3629	intracellular signal transduction
YIM_RS15775	COG3903	Transcriptional regulator
YIM_RS15780	COG0673	inositol 2-dehydrogenase activity
YIM_RS15790	COG2814	Major facilitator Superfamily
YIM_RS15795	COG0640	Transcriptional regulator
YIM_RS15815	COG1136	(ABC) transporter
YIM_RS15815	COG0577	efflux transmembrane transporter activity
YIM_RS15835	COG1309	transcriptional regulator
YIM_RS15855	COG3345	alpha-galactosidase
YIM_RS15860	COG3507	Belongs to the glycosyl hydrolase 43 family
YIM_RS15875	COG0693	protein deglycase activity
YIM_RS15910	COG0475	glutathione-regulated potassium exporter activity
YIM_RS15935	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
YIM_RS15945	COG0798	PFAM Bile acid sodium symporter
YIM_RS15995	COG1595	DNA-templated transcription, initiation
YIM_RS16010	COG0477	Major facilitator Superfamily
YIM_RS16040	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YIM_RS16070	COG0473	3-isopropylmalate dehydrogenase activity
YIM_RS16075	COG1929	Belongs to the glycerate kinase type-1 family
YIM_RS16080	COG2814	Major facilitator Superfamily
YIM_RS16090	COG3896	Chloramphenicol phosphotransferase-like protein
YIM_RS16115	COG3629	intracellular signal transduction
YIM_RS16115	COG3903	Transcriptional regulator
YIM_RS16120	COG0583	DNA-binding transcription factor activity
YIM_RS16125	COG2807	transmembrane transport
YIM_RS16185	COG3622	Belongs to the hyi family
YIM_RS16220	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
YIM_RS16225	COG0247	lactate metabolic process
YIM_RS16225	COG0277	FAD linked oxidase domain protein
YIM_RS16230	COG0179	Fumarylacetoacetate (FAA) hydrolase
YIM_RS16235	COG3622	Belongs to the hyi family
YIM_RS16240	COG2084	Dehydrogenase
YIM_RS16245	COG3960	tartronate-semialdehyde synthase activity
YIM_RS16250	COG1929	Belongs to the glycerate kinase type-1 family
YIM_RS16270	COG0454	-acetyltransferase
YIM_RS16290	COG2267	carboxylic ester hydrolase activity
YIM_RS16300	COG0667	Aldo Keto reductase
YIM_RS16315	COG0583	DNA-binding transcription factor activity
YIM_RS16320	COG0667	Aldo Keto reductase
YIM_RS16330	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
YIM_RS16335	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YIM_RS16365	COG0697	spore germination
YIM_RS16380	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YIM_RS16385	COG0747	negative chemotaxis
YIM_RS16395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YIM_RS16400	COG0444	Belongs to the ABC transporter superfamily
YIM_RS16405	COG4608	Belongs to the ABC transporter superfamily
YIM_RS16415	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YIM_RS16420	COG4948	Mandelate Racemase Muconate Lactonizing
YIM_RS16425	COG1414	Transcriptional regulator
YIM_RS16440	COG1024	Enoyl-CoA hydratase
YIM_RS16445	COG3903	Transcriptional regulator
YIM_RS16445	COG3629	intracellular signal transduction
YIM_RS16460	COG2203	Gaf domain
YIM_RS16460	COG4585	Histidine kinase
YIM_RS16480	COG3903	Transcriptional regulator
YIM_RS16480	COG3629	intracellular signal transduction
YIM_RS16485	COG3903	Transcriptional regulator
YIM_RS16485	COG3629	intracellular signal transduction
YIM_RS16490	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
YIM_RS16500	COG2197	response regulator
YIM_RS16505	COG2267	carboxylic ester hydrolase activity
YIM_RS16510	COG1764	response to oxidative stress
YIM_RS16515	COG0488	(ABC) transporter
YIM_RS16520	COG0488	(ABC) transporter
YIM_RS16530	COG2188	Transcriptional regulator
YIM_RS16535	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
YIM_RS16540	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
YIM_RS16550	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YIM_RS16555	COG1529	Aldehyde oxidase and xanthine dehydrogenase
YIM_RS16560	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
YIM_RS16565	COG2080	2 iron, 2 sulfur cluster binding
YIM_RS16570	COG1309	transcriptional regulator
YIM_RS16580	COG1960	acyl-CoA dehydrogenase activity
YIM_RS16590	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
YIM_RS16605	COG0747	negative chemotaxis
YIM_RS16610	COG0601	transmembrane transport
YIM_RS16620	COG0444	Belongs to the ABC transporter superfamily
YIM_RS16645	COG1609	Transcriptional regulator
YIM_RS16650	COG2814	Major facilitator Superfamily
YIM_RS16655	COG3940	Belongs to the glycosyl hydrolase 43 family
YIM_RS16665	COG3250	beta-galactosidase activity
YIM_RS16670	COG3540	Alkaline phosphatase
YIM_RS16710	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
YIM_RS16730	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS16745	COG2188	Transcriptional regulator
YIM_RS16750	COG1309	transcriptional regulator
YIM_RS16755	COG0604	alcohol dehydrogenase
YIM_RS16760	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS16785	COG2197	response regulator
YIM_RS16795	COG0577	efflux transmembrane transporter activity
YIM_RS16795	COG1136	(ABC) transporter
YIM_RS16800	COG0577	efflux transmembrane transporter activity
YIM_RS16815	COG0302	gtp cyclohydrolase
YIM_RS16825	COG1120	ATPase activity
YIM_RS16830	COG1108	ABC-type Mn2 Zn2 transport systems permease components
YIM_RS16865	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
YIM_RS16870	COG1309	transcriptional regulator
YIM_RS16940	COG1914	H( )-stimulated, divalent metal cation uptake system
YIM_RS16945	COG4948	Mandelate Racemase Muconate Lactonizing
YIM_RS16950	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
YIM_RS16965	COG0667	Aldo Keto reductase
YIM_RS16970	COG4608	Belongs to the ABC transporter superfamily
YIM_RS16975	COG4172	Belongs to the ABC transporter superfamily
YIM_RS16980	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YIM_RS16985	COG0601	transmembrane transport
YIM_RS16995	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
YIM_RS17000	COG1349	DNA-binding transcription factor activity
YIM_RS17005	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS17025	COG1120	ATPase activity
YIM_RS17050	COG2124	cytochrome p450
YIM_RS17065	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
YIM_RS17095	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS17120	COG1506	peptidase
YIM_RS17120	COG4946	Tricorn protease homolog
YIM_RS17120	COG0823	Involved in the tonB-independent uptake of proteins
YIM_RS17125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YIM_RS17150	COG1309	transcriptional regulator
YIM_RS17155	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS17155	COG3321	synthase
YIM_RS17155	COG0604	alcohol dehydrogenase
YIM_RS17165	COG2076	Multidrug Resistance protein
YIM_RS17175	COG0778	Nitroreductase
YIM_RS17180	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
YIM_RS17205	COG1560	Kdo2-lipid A biosynthetic process
YIM_RS17210	COG0438	transferase activity, transferring glycosyl groups
YIM_RS17225	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
YIM_RS17235	COG1733	regulation of RNA biosynthetic process
YIM_RS17245	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
YIM_RS17245	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
YIM_RS17275	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
YIM_RS17280	COG0217	transcriptional regulatory protein
YIM_RS17290	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
YIM_RS17295	COG0632	four-way junction helicase activity
YIM_RS17300	COG2255	four-way junction helicase activity
YIM_RS17315	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
YIM_RS17320	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
YIM_RS17325	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
YIM_RS17335	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
YIM_RS17355	COG1414	Transcriptional regulator
YIM_RS17360	COG0747	negative chemotaxis
YIM_RS17375	COG4172	Belongs to the ABC transporter superfamily
YIM_RS17380	COG0673	inositol 2-dehydrogenase activity
YIM_RS17425	COG2226	methyltransferase
YIM_RS17435	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
YIM_RS17480	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
YIM_RS17500	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
YIM_RS17510	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
YIM_RS17515	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
YIM_RS17520	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
YIM_RS17545	COG2124	cytochrome p450
YIM_RS17570	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YIM_RS17575	COG1263	PTS System
YIM_RS17580	COG2188	Transcriptional regulator
YIM_RS17585	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YIM_RS17620	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
YIM_RS17625	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
YIM_RS17630	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
YIM_RS17635	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
YIM_RS17640	COG0346	lactoylglutathione lyase activity
YIM_RS17655	COG0006	proline dipeptidase activity
YIM_RS17660	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
YIM_RS17665	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
YIM_RS17680	COG0540	Belongs to the ATCase OTCase family
YIM_RS17695	COG0505	Belongs to the CarA family
YIM_RS17705	COG0284	orotidine-5'-phosphate decarboxylase activity
YIM_RS17715	COG0194	GDP metabolic process
YIM_RS17720	COG1758	RNA polymerase activity
YIM_RS17730	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
YIM_RS17735	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
YIM_RS17745	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
YIM_RS17750	COG0405	Gamma-glutamyltransferase
YIM_RS17755	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
YIM_RS17790	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
YIM_RS17790	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
YIM_RS17795	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
YIM_RS17815	COG0322	excinuclease ABC activity
YIM_RS17820	COG1660	Displays ATPase and GTPase activities
YIM_RS17825	COG0391	Required for morphogenesis under gluconeogenic growth conditions
YIM_RS17830	COG1481	regulation of sporulation
YIM_RS17875	COG1280	lysine exporter protein (LysE YggA)
YIM_RS17885	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
YIM_RS17890	COG0126	phosphoglycerate kinase activity
YIM_RS17895	COG0149	triose-phosphate isomerase activity
YIM_RS17910	COG3850	Histidine kinase
YIM_RS17915	COG0363	glucosamine-6-phosphate deaminase activity
YIM_RS17930	COG0166	Belongs to the GPI family
YIM_RS17935	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
YIM_RS17945	COG0109	protoheme IX farnesyltransferase activity
YIM_RS17955	COG1733	regulation of RNA biosynthetic process
YIM_RS17960	COG3973	AAA domain
YIM_RS17965	COG0544	peptidyl-prolyl cis-trans isomerase activity
YIM_RS17970	COG0604	alcohol dehydrogenase
YIM_RS18020	COG0396	ATPase activity
YIM_RS18030	COG0822	iron-sulfur transferase activity
YIM_RS18040	COG0504	CTP synthase activity
YIM_RS18045	COG0583	DNA-binding transcription factor activity
YIM_RS18050	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
YIM_RS18055	COG4585	Histidine kinase
YIM_RS18060	COG2197	response regulator
YIM_RS18120	COG0488	(ABC) transporter
YIM_RS18135	COG1132	(ABC) transporter
YIM_RS18145	COG0596	Alpha beta hydrolase
YIM_RS18150	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
YIM_RS18155	COG1316	TRANSCRIPTIONal
YIM_RS18165	COG5001	Diguanylate cyclase
YIM_RS18175	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
YIM_RS18180	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
YIM_RS18185	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
YIM_RS18185	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
YIM_RS18195	COG1024	Enoyl-CoA hydratase
YIM_RS18215	COG1960	acyl-CoA dehydrogenase activity
YIM_RS18220	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
YIM_RS18240	COG1309	transcriptional regulator
YIM_RS18265	COG0596	Alpha beta hydrolase
YIM_RS18275	COG1309	transcriptional regulator
YIM_RS18280	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS18290	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
YIM_RS18300	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
YIM_RS18305	COG1024	Enoyl-CoA hydratase
YIM_RS18315	COG1309	transcriptional regulator
YIM_RS18325	COG1960	acyl-CoA dehydrogenase activity
YIM_RS18330	COG1960	acyl-CoA dehydrogenase activity
YIM_RS18360	COG2186	Transcriptional regulator
YIM_RS18365	COG2197	response regulator
YIM_RS18370	COG3903	Transcriptional regulator
YIM_RS18370	COG3629	intracellular signal transduction
YIM_RS18380	COG3251	PFAM MbtH domain protein
YIM_RS18420	COG0704	Plays a role in the regulation of phosphate uptake
YIM_RS18430	COG2197	response regulator
YIM_RS18445	COG2197	response regulator
YIM_RS18460	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
YIM_RS18485	COG0564	pseudouridine synthase activity
YIM_RS18515	COG1082	Xylose isomerase domain protein TIM barrel
YIM_RS18520	COG1070	Carbohydrate kinase
YIM_RS18525	COG3347	Dehydrogenase
YIM_RS18525	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS18570	COG4335	DNA alkylation repair
YIM_RS18620	COG2124	cytochrome p450
YIM_RS18630	COG0009	L-threonylcarbamoyladenylate synthase
YIM_RS18650	COG0477	Major facilitator Superfamily
YIM_RS18670	COG0628	permease
YIM_RS18680	COG0006	proline dipeptidase activity
YIM_RS18705	COG1309	transcriptional regulator
YIM_RS18730	COG1131	(ABC) transporter
YIM_RS18740	COG2197	response regulator
YIM_RS18755	COG1228	amidohydrolase
YIM_RS18765	COG4362	Belongs to the NOS family. Bacterial NOS oxygenase subfamily
YIM_RS18790	COG2271	Major facilitator Superfamily
YIM_RS18795	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YIM_RS18815	COG1366	Belongs to the anti-sigma-factor antagonist family
YIM_RS18840	COG0045	succinate-CoA ligase (ADP-forming) activity
YIM_RS18850	COG2084	Dehydrogenase
YIM_RS18855	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
YIM_RS18860	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
YIM_RS18875	COG1804	L-carnitine dehydratase bile acid-inducible protein F
YIM_RS18905	COG1802	Transcriptional regulator
YIM_RS18930	COG3383	formate dehydrogenase (NAD+) activity
YIM_RS18945	COG1280	lysine exporter protein (LysE YggA)
YIM_RS18980	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
YIM_RS18990	COG1414	Transcriptional regulator
YIM_RS19020	COG0435	Glutathione S-transferase
YIM_RS19040	COG0657	acetylesterase activity
YIM_RS19050	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
YIM_RS19055	COG0277	FAD linked oxidase domain protein
YIM_RS19065	COG2124	cytochrome p450
YIM_RS19085	COG1929	Belongs to the glycerate kinase type-1 family
YIM_RS19090	COG3960	tartronate-semialdehyde synthase activity
YIM_RS19095	COG2084	Dehydrogenase
YIM_RS19100	COG3622	Belongs to the hyi family
YIM_RS19110	COG2252	PERMEase
YIM_RS19115	COG0590	tRNA wobble adenosine to inosine editing
YIM_RS19120	COG1529	Aldehyde oxidase and xanthine dehydrogenase
YIM_RS19140	COG3835	regulator
YIM_RS19155	COG1309	transcriptional regulator
YIM_RS19170	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
YIM_RS19190	COG0028	Belongs to the TPP enzyme family
YIM_RS19195	COG0583	DNA-binding transcription factor activity
YIM_RS19200	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
YIM_RS19205	COG1053	succinate dehydrogenase
YIM_RS19215	COG0583	DNA-binding transcription factor activity
YIM_RS19225	COG2040	homocysteine
YIM_RS19235	COG0583	DNA-binding transcription factor activity
YIM_RS19260	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS19290	COG1131	(ABC) transporter
YIM_RS19300	COG1595	DNA-templated transcription, initiation
YIM_RS19325	COG1846	Transcriptional regulator
YIM_RS19370	COG2814	Major facilitator Superfamily
YIM_RS19380	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS19390	COG2936	dipeptidyl-peptidase activity
YIM_RS19395	COG0723	plastoquinol--plastocyanin reductase activity
YIM_RS19405	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS19420	COG0248	Ppx GppA phosphatase
YIM_RS19430	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
YIM_RS19440	COG1529	Aldehyde oxidase and xanthine dehydrogenase
YIM_RS19445	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
YIM_RS19450	COG2080	2 iron, 2 sulfur cluster binding
YIM_RS19455	COG0693	protein deglycase activity
YIM_RS19470	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
YIM_RS19470	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
YIM_RS19505	COG4209	transmembrane transport
YIM_RS19510	COG0395	ABC-type sugar transport system, permease component
YIM_RS19555	COG1609	Transcriptional regulator
YIM_RS19565	COG1175	transmembrane transport
YIM_RS19570	COG0395	ABC-type sugar transport system, permease component
YIM_RS19590	COG3940	Belongs to the glycosyl hydrolase 43 family
YIM_RS19605	COG0640	Transcriptional regulator
YIM_RS19620	COG4733	cellulase activity
YIM_RS19620	COG5297	Belongs to the glycosyl hydrolase family 6
YIM_RS19645	COG3842	ATPase activity
YIM_RS19650	COG2723	6-phospho-beta-galactosidase activity
YIM_RS19655	COG0395	ABC-type sugar transport system, permease component
YIM_RS19680	COG5297	Belongs to the glycosyl hydrolase family 6
YIM_RS19690	COG1335	isochorismatase
YIM_RS19700	COG0583	DNA-binding transcription factor activity
YIM_RS19710	COG1609	Transcriptional regulator
YIM_RS19740	COG1609	Transcriptional regulator
YIM_RS19760	COG1595	DNA-templated transcription, initiation
YIM_RS19800	COG3265	gluconokinase activity
YIM_RS19820	COG2814	Major facilitator Superfamily
YIM_RS19835	COG0477	Major facilitator Superfamily
YIM_RS19860	COG1609	Transcriptional regulator
YIM_RS19870	COG4948	Mandelate Racemase Muconate Lactonizing
YIM_RS19875	COG0246	Mannitol dehydrogenase
YIM_RS19885	COG0477	Major facilitator Superfamily
YIM_RS19900	COG1609	Transcriptional regulator
YIM_RS19930	COG0477	Major facilitator Superfamily
YIM_RS19940	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
YIM_RS19945	COG3185	4-Hydroxyphenylpyruvate dioxygenase
YIM_RS19945	COG1082	Xylose isomerase domain protein TIM barrel
YIM_RS20010	COG2124	cytochrome p450
YIM_RS20085	COG0583	DNA-binding transcription factor activity
YIM_RS20090	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS20145	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
YIM_RS20150	COG4608	Belongs to the ABC transporter superfamily
YIM_RS20155	COG0444	Belongs to the ABC transporter superfamily
YIM_RS20165	COG0747	negative chemotaxis
YIM_RS20170	COG2186	Transcriptional regulator
YIM_RS20195	COG0583	DNA-binding transcription factor activity
YIM_RS20205	COG2356	endonuclease I
YIM_RS20210	COG3525	Glycosyl hydrolase, family 20, catalytic domain
YIM_RS20210	COG3291	Pkd domain containing protein
YIM_RS20250	COG1302	Protein conserved in bacteria
YIM_RS20255	COG2226	methyltransferase
YIM_RS20285	COG1253	flavin adenine dinucleotide binding
YIM_RS20290	COG1253	flavin adenine dinucleotide binding
YIM_RS20355	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
YIM_RS20370	COG3321	synthase
YIM_RS20370	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
YIM_RS20370	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
YIM_RS20370	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
YIM_RS20375	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
YIM_RS20385	COG1454	alcohol dehydrogenase
YIM_RS20390	COG3958	Transketolase
YIM_RS20395	COG1454	alcohol dehydrogenase
YIM_RS20405	COG3958	Transketolase
YIM_RS20410	COG3959	Transketolase, thiamine diphosphate binding domain
YIM_RS20420	COG0006	proline dipeptidase activity
YIM_RS20425	COG1012	belongs to the aldehyde dehydrogenase family
YIM_RS20430	COG0318	PFAM AMP-dependent synthetase and ligase
YIM_RS20445	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
YIM_RS20485	COG3226	Transcriptional regulator
YIM_RS20490	COG2076	Multidrug Resistance protein
YIM_RS20495	COG2076	Multidrug Resistance protein
YIM_RS20500	COG1522	sequence-specific DNA binding
YIM_RS20505	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
YIM_RS20520	COG1335	isochorismatase
YIM_RS20530	COG1609	Transcriptional regulator
YIM_RS20535	COG1175	transmembrane transport
YIM_RS20560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YIM_RS20570	COG2084	Dehydrogenase
YIM_RS20580	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
YIM_RS20615	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
YIM_RS20620	COG3938	Belongs to the proline racemase family
YIM_RS20630	COG1024	Enoyl-CoA hydratase
YIM_RS20645	COG0667	Aldo Keto reductase
YIM_RS20655	COG0745	RESPONSE REGULATOR receiver
YIM_RS20670	COG4585	Histidine kinase
YIM_RS20675	COG2197	response regulator
YIM_RS20685	COG2814	Major facilitator Superfamily
YIM_RS20695	COG0076	glutamate decarboxylase activity
YIM_RS20710	COG3401	FG-GAP repeat protein
YIM_RS20720	COG1609	Transcriptional regulator
YIM_RS20725	COG1609	Transcriptional regulator
YIM_RS20735	COG0395	ABC-type sugar transport system, permease component
YIM_RS20740	COG1175	transmembrane transport
YIM_RS20750	COG1309	transcriptional regulator
YIM_RS20850	COG4941	Belongs to the sigma-70 factor family
YIM_RS20870	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
YIM_RS20880	COG2267	carboxylic ester hydrolase activity
YIM_RS20885	COG2197	response regulator
YIM_RS20930	COG0583	DNA-binding transcription factor activity
YIM_RS20970	COG1119	ATPase activity
YIM_RS20975	COG1309	transcriptional regulator
YIM_RS21035	COG0475	glutathione-regulated potassium exporter activity
YIM_RS21050	COG0492	ferredoxin-NADP+ reductase activity
YIM_RS21055	COG0318	PFAM AMP-dependent synthetase and ligase
YIM_RS21065	COG0583	DNA-binding transcription factor activity
YIM_RS21075	COG1802	Transcriptional regulator
YIM_RS21110	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS21130	COG1486	melibiose metabolic process
YIM_RS21135	COG1349	DNA-binding transcription factor activity
YIM_RS21140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YIM_RS21145	COG1653	transport
YIM_RS21150	COG1175	transmembrane transport
YIM_RS21155	COG0395	ABC-type sugar transport system, permease component
YIM_RS21160	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
YIM_RS21170	COG2197	response regulator
YIM_RS21180	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
YIM_RS21180	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
YIM_RS21185	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
YIM_RS21190	COG2770	Histidine kinase
YIM_RS21190	COG2208	phosphoserine phosphatase activity
YIM_RS21240	COG4977	sequence-specific DNA binding
YIM_RS21250	COG0583	DNA-binding transcription factor activity
YIM_RS21255	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YIM_RS21265	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
YIM_RS21270	COG0583	DNA-binding transcription factor activity
YIM_RS21275	COG3842	ATPase activity
YIM_RS21290	COG3833	ABC-type maltose transport systems, permease component
YIM_RS21295	COG1175	transmembrane transport
YIM_RS21310	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
YIM_RS21325	COG1609	Transcriptional regulator
YIM_RS21340	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
YIM_RS21345	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
YIM_RS21365	COG0367	asparagine synthase
YIM_RS21405	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
YIM_RS21410	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
YIM_RS21420	COG0463	Glycosyl transferase, family 2
YIM_RS21430	COG4310	Domain of unknown function (DUF2172)
YIM_RS21445	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
YIM_RS21455	COG1012	belongs to the aldehyde dehydrogenase family
YIM_RS21460	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
YIM_RS21465	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
YIM_RS21565	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
YIM_RS21600	COG1013	pyruvate-flavodoxin oxidoreductase activity
YIM_RS21605	COG0674	pyruvate-flavodoxin oxidoreductase activity
YIM_RS21605	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
YIM_RS21630	COG2267	carboxylic ester hydrolase activity
YIM_RS21640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YIM_RS21650	COG4608	Belongs to the ABC transporter superfamily
YIM_RS21660	COG1960	acyl-CoA dehydrogenase activity
YIM_RS21665	COG1960	acyl-CoA dehydrogenase activity
YIM_RS21685	COG1024	Enoyl-CoA hydratase
YIM_RS21705	COG0318	PFAM AMP-dependent synthetase and ligase
YIM_RS21715	COG1960	acyl-CoA dehydrogenase activity
YIM_RS21730	COG2030	dehydratase
YIM_RS21735	COG1960	acyl-CoA dehydrogenase activity
YIM_RS21740	COG1960	acyl-CoA dehydrogenase activity
YIM_RS21750	COG1804	L-carnitine dehydratase bile acid-inducible protein F
YIM_RS21755	COG1021	2,3-dihydroxybenzoate-AMP ligase
YIM_RS21760	COG0318	PFAM AMP-dependent synthetase and ligase
YIM_RS21765	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
YIM_RS21775	COG2124	cytochrome p450
YIM_RS21790	COG4166	transmembrane transport
YIM_RS21795	COG0747	negative chemotaxis
YIM_RS21805	COG0183	Belongs to the thiolase family
YIM_RS21810	COG0667	Aldo Keto reductase
YIM_RS21815	COG1804	L-carnitine dehydratase bile acid-inducible protein F
YIM_RS21820	COG2186	Transcriptional regulator
YIM_RS21825	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS21850	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS21890	COG2267	carboxylic ester hydrolase activity
YIM_RS21905	COG1309	transcriptional regulator
YIM_RS21940	COG3250	beta-galactosidase activity
YIM_RS21945	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS21950	COG1472	Belongs to the glycosyl hydrolase 3 family
YIM_RS21955	COG3250	beta-galactosidase activity
YIM_RS21960	COG2211	Major facilitator Superfamily
YIM_RS21975	COG0667	Aldo Keto reductase
YIM_RS22015	COG0300	oxidoreductase activity
YIM_RS22055	COG1024	Enoyl-CoA hydratase
YIM_RS22065	COG0028	Belongs to the TPP enzyme family
YIM_RS22075	COG1024	Enoyl-CoA hydratase
YIM_RS22080	COG1024	Enoyl-CoA hydratase
YIM_RS22095	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
YIM_RS22095	COG0617	tRNA 3'-terminal CCA addition
YIM_RS22095	COG0517	IMP dehydrogenase activity
YIM_RS22105	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
YIM_RS22115	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
YIM_RS22185	COG1140	nitrate reductase beta subunit
YIM_RS22225	COG3795	YCII-related domain
YIM_RS22230	COG4941	Belongs to the sigma-70 factor family
YIM_RS22245	COG0667	Aldo Keto reductase
YIM_RS22270	COG1309	transcriptional regulator
YIM_RS22280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
YIM_RS22280	COG2022	thiamine diphosphate biosynthetic process
YIM_RS22290	COG0789	Transcriptional regulator
YIM_RS22395	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
YIM_RS22425	COG1937	Protein conserved in bacteria
YIM_RS22475	COG2080	2 iron, 2 sulfur cluster binding
YIM_RS22480	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
YIM_RS22485	COG1529	Aldehyde oxidase and xanthine dehydrogenase
YIM_RS22495	COG1175	transmembrane transport
YIM_RS22500	COG0395	ABC-type sugar transport system, permease component
YIM_RS22545	COG0583	DNA-binding transcription factor activity
YIM_RS22555	COG1024	Enoyl-CoA hydratase
YIM_RS22565	COG1250	3-hydroxyacyl-CoA dehydrogenase
YIM_RS22570	COG1960	acyl-CoA dehydrogenase activity
YIM_RS22605	COG4585	Histidine kinase
YIM_RS22625	COG2986	histidine ammonia-lyase
YIM_RS22630	COG1132	(ABC) transporter
YIM_RS22650	COG0475	glutathione-regulated potassium exporter activity
YIM_RS22695	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS22730	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
YIM_RS22755	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
YIM_RS22760	COG2197	response regulator
YIM_RS22795	COG0791	NLP P60 protein
YIM_RS22795	COG1388	LysM domain
YIM_RS22795	COG3103	Sh3 type 3 domain protein
YIM_RS22800	COG2197	response regulator
YIM_RS22805	COG0477	Major facilitator Superfamily
YIM_RS22810	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
YIM_RS22815	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS22820	COG2271	Major facilitator Superfamily
YIM_RS22830	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
YIM_RS22845	COG0667	Aldo Keto reductase
YIM_RS22860	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
YIM_RS22870	COG0778	Nitroreductase
YIM_RS22875	COG0745	RESPONSE REGULATOR receiver
YIM_RS22880	COG1960	acyl-CoA dehydrogenase activity
YIM_RS22885	COG1169	isochorismate synthase
YIM_RS22905	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YIM_RS22915	COG3485	protocatechuate 3,4-dioxygenase
YIM_RS22920	COG1454	alcohol dehydrogenase
YIM_RS22930	COG1012	belongs to the aldehyde dehydrogenase family
YIM_RS22945	COG4566	intracellular signal transduction
YIM_RS22950	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
YIM_RS22955	COG0154	amidase activity
YIM_RS22995	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS23015	COG1129	ABC transporter
YIM_RS23055	COG1312	Catalyzes the dehydration of D-mannonate
YIM_RS23065	COG0477	Major facilitator Superfamily
YIM_RS23080	COG4978	Transcriptional regulator
YIM_RS23080	COG0789	Transcriptional regulator
YIM_RS23085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YIM_RS23100	COG1073	alpha beta
YIM_RS23105	COG0583	DNA-binding transcription factor activity
YIM_RS23110	COG1335	isochorismatase
YIM_RS23115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
YIM_RS23130	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
YIM_RS23175	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS23195	COG3629	intracellular signal transduction
YIM_RS23195	COG3903	Transcriptional regulator
YIM_RS23200	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YIM_RS23215	COG1309	transcriptional regulator
YIM_RS23220	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS23225	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
YIM_RS23235	COG0477	Major facilitator Superfamily
YIM_RS23245	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
YIM_RS23255	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
YIM_RS23255	COG4106	trans-aconitate 2-methyltransferase activity
YIM_RS23260	COG1278	Cold shock
YIM_RS23265	COG1802	Transcriptional regulator
YIM_RS23275	COG3842	ATPase activity
YIM_RS23285	COG1840	ABC-type Fe3 transport system, periplasmic component
YIM_RS23310	COG4948	Mandelate Racemase Muconate Lactonizing
YIM_RS23315	COG0395	ABC-type sugar transport system, permease component
YIM_RS23400	COG1960	acyl-CoA dehydrogenase activity
YIM_RS23405	COG1250	3-hydroxyacyl-CoA dehydrogenase
YIM_RS23410	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
YIM_RS23415	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
YIM_RS23420	COG0583	DNA-binding transcription factor activity
YIM_RS23425	COG0477	Major facilitator Superfamily
YIM_RS23445	COG1295	ribonuclease BN
YIM_RS23515	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
YIM_RS23530	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
YIM_RS23555	COG2030	dehydratase
YIM_RS23590	COG0583	DNA-binding transcription factor activity
YIM_RS23595	COG2211	Major facilitator Superfamily
YIM_RS23605	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
YIM_RS23615	COG0640	Transcriptional regulator
YIM_RS23645	COG2239	Acts as a magnesium transporter
YIM_RS23730	COG1126	abc transporter atp-binding protein
YIM_RS23735	COG0765	amino acid transport
YIM_RS23755	COG1024	Enoyl-CoA hydratase
YIM_RS23760	COG0318	PFAM AMP-dependent synthetase and ligase
YIM_RS23765	COG1846	Transcriptional regulator
YIM_RS23770	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
YIM_RS23785	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YIM_RS23790	COG3903	Transcriptional regulator
YIM_RS23790	COG3629	intracellular signal transduction
YIM_RS23815	COG2207	Transcriptional regulator
YIM_RS23820	COG2223	nitrite transmembrane transporter activity
YIM_RS23840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
YIM_RS23870	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
YIM_RS23885	COG4585	Histidine kinase
YIM_RS23890	COG2197	response regulator
YIM_RS23895	COG0402	S-adenosylhomocysteine deaminase activity
YIM_RS23905	COG2124	cytochrome p450
YIM_RS23925	COG1414	Transcriptional regulator
YIM_RS23980	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS23985	COG4221	oxidoreductase activity
YIM_RS23990	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
YIM_RS24005	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
YIM_RS24020	COG1349	DNA-binding transcription factor activity
YIM_RS24035	COG0395	ABC-type sugar transport system, permease component
YIM_RS24040	COG3842	ATPase activity
YIM_RS24050	COG1349	DNA-binding transcription factor activity
YIM_RS24055	COG0673	inositol 2-dehydrogenase activity
YIM_RS24070	COG1012	belongs to the aldehyde dehydrogenase family
YIM_RS24075	COG0506	proline dehydrogenase activity
YIM_RS24090	COG0667	Aldo Keto reductase
YIM_RS24095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
YIM_RS24100	COG1968	undecaprenyl-diphosphatase activity
YIM_RS24110	COG0339	signal peptide processing
YIM_RS24125	COG0039	L-malate dehydrogenase activity
YIM_RS24140	COG3537	Alpha-1,2-mannosidase
YIM_RS24145	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
YIM_RS24155	COG4166	transmembrane transport
YIM_RS24160	COG0601	transmembrane transport
YIM_RS24165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YIM_RS24195	COG1619	proteins homologs of microcin C7 resistance protein MccF
YIM_RS24290	COG0477	Major facilitator Superfamily
YIM_RS24295	COG0431	NADPH-dependent FMN reductase
YIM_RS24305	COG0702	epimerase
YIM_RS24310	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
YIM_RS24320	COG4941	Belongs to the sigma-70 factor family
YIM_RS24325	COG0667	Aldo Keto reductase
YIM_RS24360	COG0596	Alpha beta hydrolase
YIM_RS24370	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
YIM_RS24385	COG0590	tRNA wobble adenosine to inosine editing
YIM_RS24395	COG1522	sequence-specific DNA binding
YIM_RS24410	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YIM_RS24415	COG1960	acyl-CoA dehydrogenase activity
YIM_RS24420	COG4974	Belongs to the 'phage' integrase family
YIM_RS24430	COG2197	response regulator
YIM_RS24435	COG4585	Histidine kinase
YIM_RS24450	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YIM_RS24450	COG0515	serine threonine protein kinase
YIM_RS24455	COG0515	serine threonine protein kinase
YIM_RS24455	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YIM_RS24460	COG1595	DNA-templated transcription, initiation
YIM_RS24490	COG2319	Wd-40 repeat
YIM_RS24490	COG4249	Peptidase C14 caspase catalytic subunit p20
YIM_RS24525	COG2205	protein histidine kinase activity
YIM_RS24530	COG0745	RESPONSE REGULATOR receiver
YIM_RS24560	COG4221	oxidoreductase activity
YIM_RS24575	COG1725	Transcriptional regulator
YIM_RS24580	COG1131	(ABC) transporter
YIM_RS24595	COG0640	Transcriptional regulator
YIM_RS24600	COG0596	Alpha beta hydrolase
YIM_RS24605	COG0702	epimerase
YIM_RS24610	COG1733	regulation of RNA biosynthetic process
YIM_RS24625	COG4941	Belongs to the sigma-70 factor family
YIM_RS24630	COG3795	YCII-related domain
YIM_RS24660	COG0702	epimerase
YIM_RS24680	COG4941	Belongs to the sigma-70 factor family
YIM_RS24685	COG3795	YCII-related domain
YIM_RS24690	COG0596	Alpha beta hydrolase
YIM_RS24710	COG2890	protein-(glutamine-N5) methyltransferase activity
YIM_RS24785	COG0640	Transcriptional regulator
YIM_RS24805	COG1309	transcriptional regulator
YIM_RS24820	COG1435	thymidine kinase activity
YIM_RS24835	COG0463	Glycosyl transferase, family 2
YIM_RS24845	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
YIM_RS24880	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
YIM_RS24895	COG1309	transcriptional regulator
YIM_RS24915	COG0367	asparagine synthase
YIM_RS24920	COG1231	oxidoreductase activity
YIM_RS24930	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YIM_RS24935	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
YIM_RS24955	COG3483	tryptophan 2,3-dioxygenase activity
YIM_RS24960	COG3844	kynureninase activity
YIM_RS24985	COG0277	FAD linked oxidase domain protein
YIM_RS24995	COG4122	O-methyltransferase activity
YIM_RS25005	COG1063	alcohol dehydrogenase
YIM_RS25010	COG1012	belongs to the aldehyde dehydrogenase family
YIM_RS25025	COG2814	Major facilitator Superfamily
YIM_RS25040	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
YIM_RS25050	COG0583	DNA-binding transcription factor activity
YIM_RS25080	COG0436	Aminotransferase
YIM_RS25100	COG1136	(ABC) transporter
YIM_RS25130	COG2318	DinB family
YIM_RS25180	COG1733	regulation of RNA biosynthetic process
YIM_RS25195	COG0477	Major facilitator Superfamily
YIM_RS25225	COG3250	beta-galactosidase activity
YIM_RS25230	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YIM_RS25240	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS25250	COG0583	DNA-binding transcription factor activity
YIM_RS25310	COG3903	Transcriptional regulator
YIM_RS25310	COG3629	intracellular signal transduction
YIM_RS25330	COG1472	Belongs to the glycosyl hydrolase 3 family
YIM_RS25350	COG0596	Alpha beta hydrolase
YIM_RS25360	COG2318	DinB family
YIM_RS25370	COG1309	transcriptional regulator
YIM_RS25375	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS25390	COG1760	l-serine dehydratase
YIM_RS25425	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
YIM_RS25440	COG4638	Rieske (2fe-2S)
YIM_RS25445	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
YIM_RS25450	COG2146	nitrite reductase [NAD(P)H] activity
YIM_RS25455	COG1414	Transcriptional regulator
YIM_RS25460	COG0477	Major facilitator Superfamily
YIM_RS25495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
YIM_RS25510	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YIM_RS25525	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YIM_RS25530	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
YIM_RS25535	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
YIM_RS25550	COG2986	histidine ammonia-lyase
YIM_RS25560	COG1672	PFAM Archaeal ATPase
YIM_RS25560	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
YIM_RS25580	COG2814	Major facilitator Superfamily
YIM_RS25585	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
YIM_RS25610	COG2175	clavaminate synthase activity
YIM_RS25620	COG3321	synthase
YIM_RS25620	COG0604	alcohol dehydrogenase
YIM_RS25620	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS25650	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YIM_RS25660	COG3507	Belongs to the glycosyl hydrolase 43 family
YIM_RS25670	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
YIM_RS25705	COG0477	Major facilitator Superfamily
YIM_RS25715	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS25720	COG2197	response regulator
YIM_RS25725	COG4585	Histidine kinase
YIM_RS25740	COG0596	Alpha beta hydrolase
YIM_RS25780	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS25790	COG3903	Transcriptional regulator
YIM_RS25790	COG3629	intracellular signal transduction
YIM_RS25795	COG1309	transcriptional regulator
YIM_RS25810	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
YIM_RS25815	COG0477	Major facilitator Superfamily
YIM_RS25825	COG1120	ATPase activity
YIM_RS25830	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YIM_RS25835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YIM_RS25845	COG2375	cellular response to nickel ion
YIM_RS25850	COG1535	isochorismatase
YIM_RS25850	COG3433	isochorismatase activity
YIM_RS25855	COG1535	isochorismatase
YIM_RS25855	COG3433	isochorismatase activity
YIM_RS25860	COG1021	2,3-dihydroxybenzoate-AMP ligase
YIM_RS25865	COG1169	isochorismate synthase
YIM_RS25870	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS25890	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YIM_RS25920	COG0667	Aldo Keto reductase
YIM_RS25930	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
YIM_RS25950	COG0277	FAD linked oxidase domain protein
YIM_RS25965	COG0477	Major facilitator Superfamily
YIM_RS25970	COG1846	Transcriptional regulator
YIM_RS25975	COG2409	Drug exporters of the RND superfamily
YIM_RS26025	COG2723	6-phospho-beta-galactosidase activity
YIM_RS26050	COG0583	DNA-binding transcription factor activity
YIM_RS26055	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
YIM_RS26105	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YIM_RS26110	COG0697	spore germination
YIM_RS26140	COG1136	(ABC) transporter
YIM_RS26160	COG0745	RESPONSE REGULATOR receiver
YIM_RS26175	COG3395	kinase activity
YIM_RS26180	COG0235	Class ii aldolase
YIM_RS26185	COG1349	DNA-binding transcription factor activity
YIM_RS26200	COG1846	Transcriptional regulator
YIM_RS26220	COG1819	glycosyl
YIM_RS26280	COG1414	Transcriptional regulator
YIM_RS26290	COG0477	Major facilitator Superfamily
YIM_RS26295	COG1846	Transcriptional regulator
YIM_RS26300	COG1764	response to oxidative stress
YIM_RS26310	COG1280	lysine exporter protein (LysE YggA)
YIM_RS26315	COG0726	polysaccharide deacetylase
YIM_RS26330	COG3386	PFAM SMP-30 Gluconolaconase
YIM_RS26340	COG1414	Transcriptional regulator
YIM_RS26345	COG2017	converts alpha-aldose to the beta-anomer
YIM_RS26350	COG3940	Belongs to the glycosyl hydrolase 43 family
YIM_RS26365	COG1172	Belongs to the binding-protein-dependent transport system permease family
YIM_RS26370	COG1172	Belongs to the binding-protein-dependent transport system permease family
YIM_RS26380	COG1879	ABC-type sugar transport system periplasmic component
YIM_RS26385	COG1609	Transcriptional regulator
YIM_RS26420	COG0596	Alpha beta hydrolase
YIM_RS26440	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
YIM_RS26450	COG3226	Transcriptional regulator
YIM_RS26455	COG0738	Major facilitator superfamily
YIM_RS26475	COG2814	Major facilitator Superfamily
YIM_RS26480	COG1733	regulation of RNA biosynthetic process
YIM_RS26485	COG0515	serine threonine protein kinase
YIM_RS26490	COG1804	L-carnitine dehydratase bile acid-inducible protein F
YIM_RS26495	COG0277	FAD linked oxidase domain protein
YIM_RS26495	COG0247	lactate metabolic process
YIM_RS26500	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
YIM_RS26510	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
YIM_RS26515	COG2315	Protein conserved in bacteria
YIM_RS26540	COG3851	Histidine kinase
YIM_RS26545	COG2197	response regulator
YIM_RS26550	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
YIM_RS26550	COG2755	lipolytic protein G-D-S-L family
YIM_RS26560	COG1595	DNA-templated transcription, initiation
YIM_RS26575	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
YIM_RS26580	COG0789	Transcriptional regulator
YIM_RS26595	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
YIM_RS26615	COG3345	alpha-galactosidase
YIM_RS26630	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS26645	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
YIM_RS26650	COG0439	Biotin carboxylase
YIM_RS26655	COG0511	ligase activity, forming carbon-carbon bonds
YIM_RS26660	COG0825	malonyl-CoA metabolic process
YIM_RS26660	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
YIM_RS26670	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS26700	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YIM_RS26705	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
YIM_RS26715	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
YIM_RS26720	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
YIM_RS26735	COG2124	cytochrome p450
YIM_RS26745	COG0644	oxidoreductase
YIM_RS26770	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
YIM_RS26780	COG2226	methyltransferase
YIM_RS26795	COG3634	alkyl hydroperoxide reductase activity
YIM_RS26800	COG2226	methyltransferase
YIM_RS26860	COG0318	PFAM AMP-dependent synthetase and ligase
YIM_RS26865	COG2197	response regulator
YIM_RS26870	COG0596	Alpha beta hydrolase
YIM_RS26920	COG0431	NADPH-dependent FMN reductase
YIM_RS26925	COG1733	regulation of RNA biosynthetic process
YIM_RS26940	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
YIM_RS26950	COG0477	Major facilitator Superfamily
YIM_RS26960	COG2755	lipolytic protein G-D-S-L family
YIM_RS27010	COG4552	Acetyltransferase involved in intracellular survival and related
YIM_RS27050	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
YIM_RS27060	COG2378	regulation of single-species biofilm formation
YIM_RS27065	COG2378	regulation of single-species biofilm formation
YIM_RS27080	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
YIM_RS27085	COG1597	lipid kinase activity
YIM_RS27090	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
YIM_RS27095	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
YIM_RS27140	COG1222	aaa ATPase
YIM_RS27160	COG0517	IMP dehydrogenase activity
YIM_RS27160	COG1994	Peptidase M50
YIM_RS27180	COG0679	Auxin Efflux Carrier
YIM_RS27185	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
YIM_RS27190	COG0140	phosphoribosyl-ATP diphosphatase activity
YIM_RS27195	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
YIM_RS27200	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YIM_RS27205	COG0646	methionine synthase
YIM_RS27205	COG1410	methionine synthase
YIM_RS27220	COG0477	Major facilitator Superfamily
YIM_RS27225	COG2226	methyltransferase
YIM_RS27240	COG0318	PFAM AMP-dependent synthetase and ligase
YIM_RS27255	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
YIM_RS27270	COG0488	(ABC) transporter
YIM_RS27275	COG0488	(ABC) transporter
YIM_RS27280	COG0215	cysteine-tRNA ligase activity
YIM_RS27285	COG0789	Transcriptional regulator
YIM_RS27325	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
YIM_RS27335	COG1595	DNA-templated transcription, initiation
YIM_RS27340	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
YIM_RS27345	COG1309	transcriptional regulator
YIM_RS27360	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
YIM_RS27375	COG2205	protein histidine kinase activity
YIM_RS27390	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
YIM_RS27405	COG2304	oxidoreductase activity
YIM_RS27415	COG0714	Associated with various cellular activities
YIM_RS27420	COG0746	molybdenum cofactor guanylyltransferase activity
YIM_RS27430	COG3883	PFAM NLP P60 protein
YIM_RS27430	COG0791	NLP P60 protein
YIM_RS27445	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
YIM_RS27450	COG1285	pathogenesis
YIM_RS27460	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
YIM_RS27465	COG0121	glutamine amidotransferase
YIM_RS27470	COG1262	PFAM Formylglycine-generating sulfatase enzyme
YIM_RS27480	COG0583	DNA-binding transcription factor activity
YIM_RS27485	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
YIM_RS27510	COG1309	transcriptional regulator
YIM_RS27540	COG0656	L-ascorbic acid biosynthetic process
YIM_RS27565	COG1309	transcriptional regulator
YIM_RS27580	COG1716	ATPase activity
YIM_RS27585	COG0509	glycine decarboxylation via glycine cleavage system
YIM_RS27605	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
YIM_RS27615	COG2267	carboxylic ester hydrolase activity
YIM_RS27620	COG1648	precorrin-2 dehydrogenase activity
YIM_RS27620	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
YIM_RS27650	COG0227	Belongs to the bacterial ribosomal protein bL28 family
YIM_RS27655	COG0267	Belongs to the bacterial ribosomal protein bL33 family
YIM_RS27660	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
YIM_RS27665	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
YIM_RS27670	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
YIM_RS27700	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
YIM_RS27735	COG1132	(ABC) transporter
YIM_RS27740	COG1309	transcriptional regulator
YIM_RS27795	COG1472	Belongs to the glycosyl hydrolase 3 family
YIM_RS27805	COG1477	protein flavinylation
YIM_RS27820	COG0745	RESPONSE REGULATOR receiver
YIM_RS27825	COG2205	protein histidine kinase activity
YIM_RS27835	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YIM_RS27845	COG1309	transcriptional regulator
YIM_RS27850	COG3246	L-lysine catabolic process to acetate
YIM_RS27855	COG1250	3-hydroxyacyl-CoA dehydrogenase
YIM_RS27860	COG3842	ATPase activity
YIM_RS27870	COG1486	melibiose metabolic process
YIM_RS27875	COG0395	ABC-type sugar transport system, permease component
YIM_RS27880	COG1175	transmembrane transport
YIM_RS27890	COG1940	carbohydrate kinase activity
YIM_RS27900	COG0488	(ABC) transporter
YIM_RS27905	COG0640	Transcriptional regulator
YIM_RS27960	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
YIM_RS27965	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
YIM_RS27995	COG4702	Belongs to the UPF0303 family
YIM_RS28005	COG0133	tryptophan synthase activity
YIM_RS28015	COG1234	tRNA 3'-trailer cleavage
YIM_RS28030	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
YIM_RS28050	COG4585	Histidine kinase
YIM_RS28055	COG2197	response regulator
YIM_RS28060	COG0439	Biotin carboxylase
YIM_RS28065	COG5650	phosphatidylinositol metabolic process
YIM_RS28070	COG2197	response regulator
YIM_RS28075	COG4585	Histidine kinase
YIM_RS28080	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
YIM_RS28105	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
YIM_RS28110	COG4585	Histidine kinase
YIM_RS28115	COG2197	response regulator
YIM_RS28120	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
YIM_RS28130	COG0596	Alpha beta hydrolase
YIM_RS28150	COG1595	DNA-templated transcription, initiation
YIM_RS28175	COG0154	amidase activity
YIM_RS28180	COG1252	NADH dehydrogenase
YIM_RS28205	COG1960	acyl-CoA dehydrogenase activity
YIM_RS28220	COG1357	PFAM Pentapeptide repeats (8 copies)
YIM_RS28250	COG1131	(ABC) transporter
YIM_RS28255	COG1725	Transcriptional regulator
YIM_RS28285	COG3629	intracellular signal transduction
YIM_RS28285	COG3903	Transcriptional regulator
YIM_RS28330	COG1309	transcriptional regulator
YIM_RS28340	COG3629	intracellular signal transduction
YIM_RS28340	COG3903	Transcriptional regulator
YIM_RS28380	COG1846	Transcriptional regulator
YIM_RS28385	COG0318	PFAM AMP-dependent synthetase and ligase
YIM_RS28395	COG1940	carbohydrate kinase activity
YIM_RS28395	COG1846	Transcriptional regulator
YIM_RS28400	COG0395	ABC-type sugar transport system, permease component
YIM_RS28405	COG1175	transmembrane transport
YIM_RS28420	COG1082	Xylose isomerase domain protein TIM barrel
YIM_RS28425	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
YIM_RS28445	COG2267	carboxylic ester hydrolase activity
YIM_RS28465	COG2814	Major facilitator Superfamily
YIM_RS28475	COG2851	Citrate transporter
YIM_RS28495	COG1653	transport
YIM_RS28510	COG0515	serine threonine protein kinase
YIM_RS28540	COG3345	alpha-galactosidase
YIM_RS28545	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
YIM_RS28560	COG2197	response regulator
YIM_RS28565	COG3903	Transcriptional regulator
YIM_RS28565	COG3629	intracellular signal transduction
YIM_RS28595	COG4104	PAAR repeat-containing protein
YIM_RS28595	COG3209	COG3209 Rhs family protein
YIM_RS28695	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
YIM_RS28770	COG0604	alcohol dehydrogenase
YIM_RS28770	COG3321	synthase
YIM_RS28770	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS28780	COG3321	synthase
YIM_RS28780	COG0604	alcohol dehydrogenase
YIM_RS28785	COG1309	transcriptional regulator
YIM_RS28810	COG4585	Histidine kinase
YIM_RS28850	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
YIM_RS28855	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YIM_RS28895	COG0596	Alpha beta hydrolase
YIM_RS28900	COG1335	isochorismatase
YIM_RS28925	COG0477	Major facilitator Superfamily
YIM_RS28940	COG2309	aminopeptidase activity
YIM_RS28950	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YIM_RS28960	COG1397	ADP-ribosylglycohydrolase
YIM_RS29030	COG0584	glycerophosphoryl diester phosphodiesterase
YIM_RS29045	COG1132	(ABC) transporter
YIM_RS29050	COG1132	(ABC) transporter
YIM_RS29055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
YIM_RS29105	COG1250	3-hydroxyacyl-CoA dehydrogenase
YIM_RS29115	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS29130	COG2124	cytochrome p450
YIM_RS29150	COG3321	synthase
YIM_RS29150	COG0604	alcohol dehydrogenase
YIM_RS29155	COG3321	synthase
YIM_RS29155	COG0604	alcohol dehydrogenase
YIM_RS29175	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS29205	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
YIM_RS29210	COG0540	Belongs to the ATCase OTCase family
YIM_RS29230	COG1012	belongs to the aldehyde dehydrogenase family
YIM_RS29260	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
YIM_RS29260	COG0028	Belongs to the TPP enzyme family
YIM_RS29270	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
YIM_RS29280	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
YIM_RS29305	COG1960	acyl-CoA dehydrogenase activity
YIM_RS29315	COG1063	alcohol dehydrogenase
YIM_RS29320	COG1021	2,3-dihydroxybenzoate-AMP ligase
YIM_RS29345	COG1960	acyl-CoA dehydrogenase activity
YIM_RS29370	COG1960	acyl-CoA dehydrogenase activity
YIM_RS29375	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS29385	COG1024	Enoyl-CoA hydratase
YIM_RS29390	COG0477	Major facilitator Superfamily
YIM_RS29420	COG0494	nUDIX hydrolase
YIM_RS29425	COG0154	amidase activity
YIM_RS29525	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
YIM_RS29540	COG1674	ftsk spoiiie
YIM_RS29595	COG2259	Doxx family
YIM_RS29615	COG0484	heat shock protein binding
YIM_RS29630	COG1309	transcriptional regulator
YIM_RS29640	COG0596	Alpha beta hydrolase
YIM_RS29650	COG0583	DNA-binding transcription factor activity
YIM_RS29665	COG1733	regulation of RNA biosynthetic process
YIM_RS29680	COG1804	L-carnitine dehydratase bile acid-inducible protein F
YIM_RS29685	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
YIM_RS29705	COG4948	Mandelate Racemase Muconate Lactonizing
YIM_RS29715	COG2271	Major facilitator Superfamily
YIM_RS29720	COG1802	Transcriptional regulator
YIM_RS29740	COG2205	protein histidine kinase activity
YIM_RS29745	COG0745	RESPONSE REGULATOR receiver
YIM_RS29755	COG0789	Transcriptional regulator
YIM_RS29760	COG3209	COG3209 Rhs family protein
YIM_RS29780	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
YIM_RS29790	COG3958	Transketolase
YIM_RS29795	COG3959	Transketolase, thiamine diphosphate binding domain
YIM_RS29815	COG0477	Major facilitator Superfamily
YIM_RS29860	COG0243	molybdopterin cofactor binding
YIM_RS29865	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
YIM_RS29875	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS29880	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS29885	COG0583	DNA-binding transcription factor activity
YIM_RS29890	COG0574	Belongs to the PEP-utilizing enzyme family
YIM_RS29890	COG3848	Pyruvate phosphate dikinase
YIM_RS29905	COG1529	Aldehyde oxidase and xanthine dehydrogenase
YIM_RS29910	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
YIM_RS29915	COG2080	2 iron, 2 sulfur cluster binding
YIM_RS29925	COG2072	flavoprotein involved in K transport
YIM_RS29930	COG2186	Transcriptional regulator
YIM_RS29940	COG1172	Belongs to the binding-protein-dependent transport system permease family
YIM_RS29945	COG1129	ABC transporter
YIM_RS29980	COG0318	PFAM AMP-dependent synthetase and ligase
YIM_RS29985	COG2072	flavoprotein involved in K transport
YIM_RS30005	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS30025	COG2072	flavoprotein involved in K transport
YIM_RS30045	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS30060	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YIM_RS30070	COG1846	Transcriptional regulator
YIM_RS30080	COG3226	Transcriptional regulator
YIM_RS30085	COG0515	serine threonine protein kinase
YIM_RS30085	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YIM_RS30100	COG1959	2 iron, 2 sulfur cluster binding
YIM_RS30105	COG2815	serine threonine protein kinase
YIM_RS30105	COG0515	serine threonine protein kinase
YIM_RS30205	COG1929	Belongs to the glycerate kinase type-1 family
YIM_RS30210	COG1408	metallophosphoesterase
YIM_RS30215	COG1063	alcohol dehydrogenase
YIM_RS30220	COG0179	Fumarylacetoacetate (FAA) hydrolase
YIM_RS30225	COG1414	Transcriptional regulator
YIM_RS30230	COG0129	dihydroxy-acid dehydratase activity
YIM_RS30255	COG2267	carboxylic ester hydrolase activity
YIM_RS30275	COG0454	-acetyltransferase
YIM_RS30320	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
YIM_RS30325	COG0515	serine threonine protein kinase
YIM_RS30335	COG1609	Transcriptional regulator
YIM_RS30345	COG1733	regulation of RNA biosynthetic process
YIM_RS30355	COG2084	Dehydrogenase
YIM_RS30375	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
YIM_RS30385	COG0477	Major facilitator Superfamily
YIM_RS30440	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS30460	COG1012	belongs to the aldehyde dehydrogenase family
YIM_RS30465	COG0179	Fumarylacetoacetate (FAA) hydrolase
YIM_RS30470	COG1802	Transcriptional regulator
YIM_RS30475	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
YIM_RS30480	COG1012	belongs to the aldehyde dehydrogenase family
YIM_RS30495	COG3903	Transcriptional regulator
YIM_RS30495	COG3629	intracellular signal transduction
YIM_RS30525	COG5650	phosphatidylinositol metabolic process
YIM_RS30530	COG0174	glutamine synthetase
YIM_RS30550	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
YIM_RS30555	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
YIM_RS30570	COG2326	polyphosphate kinase activity
YIM_RS30575	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
YIM_RS30590	COG0488	(ABC) transporter
YIM_RS30610	COG1595	DNA-templated transcription, initiation
YIM_RS30620	COG1302	Protein conserved in bacteria
YIM_RS30665	COG1793	dna ligase
YIM_RS30685	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YIM_RS30690	COG0398	Pfam SNARE associated Golgi protein
YIM_RS30695	COG2815	serine threonine protein kinase
YIM_RS30695	COG0515	serine threonine protein kinase
YIM_RS30715	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
YIM_RS30735	COG3220	belongs to the UPF0276 family
YIM_RS30745	COG1804	L-carnitine dehydratase bile acid-inducible protein F
YIM_RS30755	COG3253	May function as heme-dependent peroxidase
YIM_RS30760	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
YIM_RS30765	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
YIM_RS30775	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
YIM_RS30780	COG3766	membrane
YIM_RS30800	COG2197	response regulator
YIM_RS30830	COG0183	Belongs to the thiolase family
YIM_RS30835	COG1024	Enoyl-CoA hydratase
YIM_RS30835	COG1250	3-hydroxyacyl-CoA dehydrogenase
YIM_RS30855	COG2205	protein histidine kinase activity
YIM_RS30860	COG0745	RESPONSE REGULATOR receiver
YIM_RS30890	COG1012	belongs to the aldehyde dehydrogenase family
YIM_RS30915	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
YIM_RS30925	COG2755	lipolytic protein G-D-S-L family
YIM_RS30925	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
YIM_RS30930	COG1012	belongs to the aldehyde dehydrogenase family
YIM_RS30945	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
YIM_RS30950	COG0531	amino acid
YIM_RS30955	COG0569	domain protein
YIM_RS30985	COG1280	lysine exporter protein (LysE YggA)
YIM_RS30995	COG0756	dUTP diphosphatase activity
YIM_RS31015	COG0483	inositol monophosphate 1-phosphatase activity
YIM_RS31035	COG1733	regulation of RNA biosynthetic process
YIM_RS31040	COG0488	(ABC) transporter
YIM_RS31045	COG1940	carbohydrate kinase activity
YIM_RS31050	COG1309	transcriptional regulator
YIM_RS31055	COG2124	cytochrome p450
YIM_RS31075	COG1160	GTP binding
YIM_RS31095	COG0475	glutathione-regulated potassium exporter activity
YIM_RS31110	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
YIM_RS31115	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
YIM_RS31140	COG0494	nUDIX hydrolase
YIM_RS31145	COG0504	CTP synthase activity
YIM_RS31150	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
YIM_RS31170	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
YIM_RS31185	COG0647	UMP catabolic process
YIM_RS31210	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
YIM_RS31215	COG2094	Belongs to the DNA glycosylase MPG family
YIM_RS31240	COG0165	Argininosuccinate lyase
YIM_RS31245	COG1438	arginine binding
YIM_RS31255	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
YIM_RS31260	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
YIM_RS31265	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
YIM_RS31270	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
YIM_RS31285	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
YIM_RS31285	COG0072	phenylalanine-tRNA ligase activity
YIM_RS31290	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
YIM_RS31295	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YIM_RS31300	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
YIM_RS31305	COG0291	Belongs to the bacterial ribosomal protein bL35 family
YIM_RS31325	COG2515	1-aminocyclopropane-1-carboxylate deaminase
YIM_RS31350	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
YIM_RS31355	COG2610	gluconate transmembrane transporter activity
YIM_RS31360	COG2706	6-phosphogluconolactonase activity
YIM_RS31370	COG1175	transmembrane transport
YIM_RS31375	COG0395	ABC-type sugar transport system, permease component
YIM_RS31385	COG1051	belongs to the nudix hydrolase family
YIM_RS31400	COG1316	TRANSCRIPTIONal
YIM_RS31415	COG3290	protein histidine kinase activity
YIM_RS31420	COG1301	dicarboxylic acid transport
YIM_RS31490	COG3285	dna ligase
YIM_RS31490	COG1793	dna ligase
YIM_RS31510	COG0640	Transcriptional regulator
YIM_RS31520	COG1126	abc transporter atp-binding protein
YIM_RS31525	COG0765	amino acid transport
YIM_RS31530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YIM_RS31545	COG3250	beta-galactosidase activity
YIM_RS31565	COG0702	epimerase
YIM_RS31570	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
YIM_RS31590	COG0667	Aldo Keto reductase
YIM_RS31600	COG1070	Carbohydrate kinase
YIM_RS31610	COG1609	Transcriptional regulator
YIM_RS31615	COG1879	ABC-type sugar transport system periplasmic component
YIM_RS31620	COG1172	Belongs to the binding-protein-dependent transport system permease family
YIM_RS31625	COG1129	ABC transporter
YIM_RS31650	COG0823	Involved in the tonB-independent uptake of proteins
YIM_RS31650	COG4946	Tricorn protease homolog
YIM_RS31650	COG1506	peptidase
YIM_RS31660	COG1131	(ABC) transporter
YIM_RS31700	COG1515	deoxyribonuclease V activity
YIM_RS31705	COG1131	(ABC) transporter
YIM_RS31720	COG4585	Histidine kinase
YIM_RS31725	COG2197	response regulator
YIM_RS31730	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
YIM_RS31730	COG0237	dephospho-CoA kinase activity
YIM_RS31745	COG3321	synthase
YIM_RS31745	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS31745	COG0604	alcohol dehydrogenase
YIM_RS31755	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
YIM_RS31760	COG2267	carboxylic ester hydrolase activity
YIM_RS31765	COG1819	glycosyl
YIM_RS31780	COG0539	negative regulation of cytoplasmic translation
YIM_RS31785	COG2226	methyltransferase
YIM_RS31805	COG1511	domain protein
YIM_RS31850	COG2050	protein possibly involved in aromatic compounds catabolism
YIM_RS31855	COG0583	DNA-binding transcription factor activity
YIM_RS31900	COG0582	viral genome integration into host DNA
YIM_RS31945	COG1674	ftsk spoiiie
YIM_RS32015	COG2124	cytochrome p450
YIM_RS32020	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS32095	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
YIM_RS32125	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
YIM_RS32135	COG1960	acyl-CoA dehydrogenase activity
YIM_RS32155	COG3903	Transcriptional regulator
YIM_RS32155	COG3629	intracellular signal transduction
YIM_RS32160	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
YIM_RS32165	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
YIM_RS32170	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
YIM_RS32245	COG1063	alcohol dehydrogenase
YIM_RS32250	COG0477	Major facilitator Superfamily
YIM_RS32255	COG0246	Mannitol dehydrogenase
YIM_RS32275	COG1733	regulation of RNA biosynthetic process
YIM_RS32290	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
YIM_RS32300	COG0297	glycogen (starch) synthase activity
YIM_RS32350	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YIM_RS32370	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
YIM_RS32375	COG0395	ABC-type sugar transport system, permease component
YIM_RS32385	COG2186	Transcriptional regulator
YIM_RS32390	COG4948	Mandelate Racemase Muconate Lactonizing
YIM_RS32400	COG4221	oxidoreductase activity
YIM_RS32405	COG2159	amidohydrolase
YIM_RS32415	COG2723	6-phospho-beta-galactosidase activity
YIM_RS32420	COG3250	beta-galactosidase activity
YIM_RS32425	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
YIM_RS32440	COG2084	Dehydrogenase
YIM_RS32445	COG0601	transmembrane transport
YIM_RS32485	COG3401	FG-GAP repeat protein
YIM_RS32490	COG3250	beta-galactosidase activity
YIM_RS32500	COG1175	transmembrane transport
YIM_RS32505	COG0395	ABC-type sugar transport system, permease component
YIM_RS32585	COG4585	Histidine kinase
YIM_RS32590	COG2197	response regulator
YIM_RS32600	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
YIM_RS32605	COG2197	response regulator
YIM_RS32655	COG2936	dipeptidyl-peptidase activity
YIM_RS32660	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
YIM_RS32680	COG3629	intracellular signal transduction
YIM_RS32680	COG3903	Transcriptional regulator
YIM_RS32745	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
YIM_RS32750	COG0604	alcohol dehydrogenase
YIM_RS32750	COG3321	synthase
YIM_RS32750	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS32770	COG4249	Peptidase C14 caspase catalytic subunit p20
YIM_RS32770	COG2319	Wd-40 repeat
YIM_RS32790	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YIM_RS32795	COG0789	Transcriptional regulator
YIM_RS32810	COG1309	transcriptional regulator
YIM_RS32815	COG1609	Transcriptional regulator
YIM_RS32820	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
YIM_RS32825	COG1914	H( )-stimulated, divalent metal cation uptake system
YIM_RS32840	COG2226	methyltransferase
YIM_RS32850	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
YIM_RS32855	COG2390	Transcriptional regulator
YIM_RS32860	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YIM_RS32870	COG3732	PTS system glucitol sorbitol-specific
YIM_RS32890	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
YIM_RS32895	COG0508	dehydrogenase complex catalyzes the overall conversion of
YIM_RS32895	COG0022	dehydrogenase e1 component
YIM_RS32900	COG0508	dehydrogenase complex catalyzes the overall conversion of
YIM_RS32905	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
YIM_RS32950	COG1529	Aldehyde oxidase and xanthine dehydrogenase
YIM_RS32955	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
YIM_RS32960	COG2080	2 iron, 2 sulfur cluster binding
YIM_RS32970	COG1960	acyl-CoA dehydrogenase activity
YIM_RS32980	COG1960	acyl-CoA dehydrogenase activity
YIM_RS32985	COG1024	Enoyl-CoA hydratase
YIM_RS32990	COG0318	PFAM AMP-dependent synthetase and ligase
YIM_RS32995	COG1960	acyl-CoA dehydrogenase activity
YIM_RS33005	COG0183	Belongs to the thiolase family
YIM_RS33010	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
YIM_RS33030	COG1024	Enoyl-CoA hydratase
YIM_RS33035	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS33040	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS33070	COG1309	transcriptional regulator
YIM_RS33080	COG0604	alcohol dehydrogenase
YIM_RS33110	COG1940	carbohydrate kinase activity
YIM_RS33110	COG1846	Transcriptional regulator
YIM_RS33140	COG3706	GGDEF domain
YIM_RS33150	COG2272	Belongs to the type-B carboxylesterase lipase family
YIM_RS33185	COG1131	(ABC) transporter
YIM_RS33195	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
YIM_RS33200	COG0257	Belongs to the bacterial ribosomal protein bL36 family
YIM_RS33205	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
YIM_RS33210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YIM_RS33215	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YIM_RS33220	COG1120	ATPase activity
YIM_RS33235	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
YIM_RS33240	COG0859	PFAM glycosyl transferase family 9
YIM_RS33250	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
YIM_RS33250	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
YIM_RS33255	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
YIM_RS33265	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
YIM_RS33270	COG2192	nodulation
YIM_RS33275	COG0438	transferase activity, transferring glycosyl groups
YIM_RS33285	COG1215	transferase activity, transferring glycosyl groups
YIM_RS33305	COG2890	protein-(glutamine-N5) methyltransferase activity
YIM_RS33330	COG3546	catalase activity
YIM_RS33360	COG0148	phosphopyruvate hydratase activity
YIM_RS33370	COG0748	coenzyme F420 binding
YIM_RS33395	COG0300	oxidoreductase activity
YIM_RS33405	COG3257	ureidoglycine aminohydrolase activity
YIM_RS33410	COG3835	regulator
YIM_RS33445	COG0318	PFAM AMP-dependent synthetase and ligase
YIM_RS33455	COG0477	Major facilitator Superfamily
YIM_RS33460	COG2409	Drug exporters of the RND superfamily
YIM_RS33530	COG1234	tRNA 3'-trailer cleavage
YIM_RS33550	COG1309	transcriptional regulator
YIM_RS33565	COG4555	ABC transporter
YIM_RS33605	COG4552	Acetyltransferase involved in intracellular survival and related
YIM_RS33620	COG3903	Transcriptional regulator
YIM_RS33620	COG3629	intracellular signal transduction
YIM_RS33655	COG0628	permease
YIM_RS33660	COG2409	Drug exporters of the RND superfamily
YIM_RS33675	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
YIM_RS33680	COG0477	Major facilitator Superfamily
YIM_RS33705	COG1309	transcriptional regulator
YIM_RS33720	COG3903	Transcriptional regulator
YIM_RS33720	COG3629	intracellular signal transduction
YIM_RS33730	COG0596	Alpha beta hydrolase
YIM_RS33735	COG0789	Transcriptional regulator
YIM_RS33745	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
YIM_RS33745	COG0481	GTPase activity
YIM_RS33765	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
YIM_RS33790	COG4585	Histidine kinase
YIM_RS33795	COG2197	response regulator
YIM_RS33800	COG0596	Alpha beta hydrolase
YIM_RS33815	COG0789	Transcriptional regulator
YIM_RS33830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YIM_RS33840	COG2318	DinB family
YIM_RS33915	COG4585	Histidine kinase
YIM_RS33920	COG2197	response regulator
YIM_RS33940	COG2814	Major facilitator Superfamily
YIM_RS33970	COG1595	DNA-templated transcription, initiation
YIM_RS33990	COG4638	Rieske (2fe-2S)
YIM_RS33995	COG2264	protein methyltransferase activity
YIM_RS34005	COG0604	alcohol dehydrogenase
YIM_RS34010	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS34035	COG0477	Major facilitator Superfamily
YIM_RS34045	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
YIM_RS34045	COG2755	lipolytic protein G-D-S-L family
YIM_RS34055	COG2205	protein histidine kinase activity
YIM_RS34060	COG0745	RESPONSE REGULATOR receiver
YIM_RS34115	COG1733	regulation of RNA biosynthetic process
YIM_RS34170	COG1574	metal-dependent hydrolase with the TIM-barrel fold
YIM_RS34185	COG3509	depolymerase
YIM_RS34190	COG2755	lipolytic protein G-D-S-L family
YIM_RS34205	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS34210	COG0583	DNA-binding transcription factor activity
YIM_RS34280	COG3903	Transcriptional regulator
YIM_RS34280	COG3629	intracellular signal transduction
YIM_RS34305	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YIM_RS34320	COG0025	NhaP-type Na H and K H
YIM_RS34350	COG2186	Transcriptional regulator
YIM_RS34355	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
YIM_RS34385	COG1695	Transcriptional regulator
YIM_RS34395	COG1113	amino acid transport
YIM_RS34400	COG0745	RESPONSE REGULATOR receiver
YIM_RS34405	COG2205	protein histidine kinase activity
YIM_RS34460	COG1132	(ABC) transporter
YIM_RS34460	COG2375	cellular response to nickel ion
YIM_RS34465	COG1132	(ABC) transporter
YIM_RS34485	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS34505	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
YIM_RS34510	COG1674	ftsk spoiiie
YIM_RS34530	COG4667	esterase of the alpha-beta hydrolase superfamily
YIM_RS34555	COG0583	DNA-binding transcription factor activity
YIM_RS34570	COG3629	intracellular signal transduction
YIM_RS34570	COG3903	Transcriptional regulator
YIM_RS34580	COG1136	(ABC) transporter
YIM_RS34605	COG3209	COG3209 Rhs family protein
YIM_RS34625	COG2205	protein histidine kinase activity
YIM_RS34630	COG0745	RESPONSE REGULATOR receiver
YIM_RS34635	COG2271	Major facilitator Superfamily
YIM_RS34645	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
YIM_RS34650	COG1024	Enoyl-CoA hydratase
YIM_RS34660	COG1024	Enoyl-CoA hydratase
YIM_RS34665	COG0318	PFAM AMP-dependent synthetase and ligase
YIM_RS34690	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
YIM_RS34735	COG1804	L-carnitine dehydratase bile acid-inducible protein F
YIM_RS34740	COG2301	Belongs to the HpcH HpaI aldolase family
YIM_RS34750	COG2079	MmgE PrpD family protein
YIM_RS34780	COG3866	Pectate lyase
YIM_RS34795	COG0395	ABC-type sugar transport system, permease component
YIM_RS34810	COG1959	2 iron, 2 sulfur cluster binding
YIM_RS34815	COG4941	Belongs to the sigma-70 factor family
YIM_RS34875	COG0456	acetyltransferase
YIM_RS34880	COG0740	serine-type endopeptidase activity
YIM_RS34890	COG1309	transcriptional regulator
YIM_RS34895	COG5001	Diguanylate cyclase
YIM_RS34905	COG2124	cytochrome p450
YIM_RS34935	COG1414	Transcriptional regulator
YIM_RS34960	COG0346	lactoylglutathione lyase activity
YIM_RS34995	COG2080	2 iron, 2 sulfur cluster binding
YIM_RS35000	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
YIM_RS35010	COG1529	Aldehyde oxidase and xanthine dehydrogenase
YIM_RS35015	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
YIM_RS35020	COG2318	DinB family
YIM_RS35025	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
YIM_RS35065	COG1725	Transcriptional regulator
YIM_RS35080	COG0022	dehydrogenase e1 component
YIM_RS35085	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
YIM_RS35090	COG3199	ATP-NAD kinase
YIM_RS35095	COG4221	oxidoreductase activity
YIM_RS35120	COG0514	ATP-dependent DNA helicase (RecQ)
YIM_RS35125	COG3537	Alpha-1,2-mannosidase
YIM_RS35145	COG1132	(ABC) transporter
YIM_RS35175	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YIM_RS35180	COG2226	methyltransferase
YIM_RS35190	COG1309	transcriptional regulator
YIM_RS35195	COG0508	dehydrogenase complex catalyzes the overall conversion of
YIM_RS35210	COG1522	sequence-specific DNA binding
YIM_RS35230	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
YIM_RS35255	COG1492	cobalamin metabolic process
YIM_RS35260	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
YIM_RS35270	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
YIM_RS35275	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
YIM_RS35290	COG1797	cobyrinic acid a,c-diamide synthase activity
YIM_RS35340	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
YIM_RS35345	COG1131	(ABC) transporter
YIM_RS35355	COG1476	TRANSCRIPTIONal
YIM_RS35390	COG0640	Transcriptional regulator
YIM_RS35395	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YIM_RS35415	COG0248	Ppx GppA phosphatase
YIM_RS35430	COG0768	penicillin binding
YIM_RS35440	COG0275	rRNA processing
YIM_RS35445	COG2001	Belongs to the MraZ family
YIM_RS35470	COG0714	Associated with various cellular activities
YIM_RS35480	COG1305	Transglutaminase-like
YIM_RS35490	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
YIM_RS35500	COG2151	metal-sulfur cluster biosynthetic enzyme
YIM_RS35500	COG0489	protein tyrosine kinase activity
YIM_RS35505	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
YIM_RS35510	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
YIM_RS35515	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YIM_RS35520	COG0167	dihydroorotate dehydrogenase activity
YIM_RS35535	COG1842	Phage shock protein A
YIM_RS35540	COG1396	sequence-specific DNA binding
YIM_RS35545	COG1058	Belongs to the CinA family
YIM_RS35545	COG1546	Belongs to the CinA family
YIM_RS35555	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
YIM_RS35560	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
YIM_RS35580	COG0778	Nitroreductase
YIM_RS35585	COG1674	ftsk spoiiie
YIM_RS35610	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
YIM_RS35615	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
YIM_RS35620	COG0515	serine threonine protein kinase
YIM_RS35620	COG2815	serine threonine protein kinase
YIM_RS35650	COG1672	PFAM Archaeal ATPase
YIM_RS35650	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
YIM_RS35660	COG0477	Major facilitator Superfamily
YIM_RS35665	COG3214	Protein conserved in bacteria
YIM_RS35690	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
YIM_RS35695	COG0612	Peptidase, M16
YIM_RS35700	COG1185	polyribonucleotide nucleotidyltransferase activity
YIM_RS35705	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
YIM_RS35725	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
YIM_RS35765	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
YIM_RS35780	COG0477	Major facilitator Superfamily
YIM_RS35800	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
YIM_RS35815	COG0779	Required for maturation of 30S ribosomal subunits
YIM_RS35830	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
YIM_RS35870	COG4585	Histidine kinase
YIM_RS35875	COG2197	response regulator
YIM_RS35880	COG1733	regulation of RNA biosynthetic process
YIM_RS35885	COG0702	epimerase
YIM_RS35900	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
YIM_RS35900	COG1672	PFAM Archaeal ATPase
YIM_RS35910	COG2936	dipeptidyl-peptidase activity
YIM_RS35915	COG0667	Aldo Keto reductase
YIM_RS35935	COG2022	thiamine diphosphate biosynthetic process
YIM_RS35945	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YIM_RS35950	COG1410	methionine synthase
YIM_RS35950	COG0646	methionine synthase
YIM_RS35970	COG2409	Drug exporters of the RND superfamily
YIM_RS35995	COG0626	cystathionine gamma-synthase activity
YIM_RS36015	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YIM_RS36030	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
YIM_RS36060	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
YIM_RS36080	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
YIM_RS36085	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
YIM_RS36095	COG0328	RNA-DNA hybrid ribonuclease activity
YIM_RS36145	COG2115	Belongs to the xylose isomerase family
YIM_RS36175	COG0367	asparagine synthase
YIM_RS36195	COG1793	dna ligase
YIM_RS36195	COG3285	dna ligase
YIM_RS36255	COG0583	DNA-binding transcription factor activity
YIM_RS36260	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YIM_RS36280	COG2072	flavoprotein involved in K transport
YIM_RS36330	COG1181	Belongs to the D-alanine--D-alanine ligase family
YIM_RS36335	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
YIM_RS36345	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
YIM_RS36350	COG2205	protein histidine kinase activity
YIM_RS36355	COG0745	RESPONSE REGULATOR receiver
YIM_RS36380	COG0025	NhaP-type Na H and K H
YIM_RS36385	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
YIM_RS36390	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
YIM_RS36395	COG4585	Histidine kinase
YIM_RS36400	COG2197	response regulator
YIM_RS36415	COG1132	(ABC) transporter
YIM_RS36425	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
YIM_RS36445	COG3631	Ketosteroid isomerase-related protein
YIM_RS36470	COG0346	lactoylglutathione lyase activity
YIM_RS36475	COG2072	flavoprotein involved in K transport
YIM_RS36495	COG0667	Aldo Keto reductase
YIM_RS36510	COG0444	Belongs to the ABC transporter superfamily
YIM_RS36515	COG0747	negative chemotaxis
YIM_RS36525	COG0601	transmembrane transport
YIM_RS36545	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS36550	COG3976	FMN-binding domain protein
YIM_RS36550	COG1053	succinate dehydrogenase
YIM_RS36595	COG1024	Enoyl-CoA hydratase
YIM_RS36605	COG1414	Transcriptional regulator
YIM_RS36615	COG1804	L-carnitine dehydratase bile acid-inducible protein F
YIM_RS36625	COG1960	acyl-CoA dehydrogenase activity
YIM_RS36645	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS36655	COG1218	3'(2'),5'-bisphosphate nucleotidase
YIM_RS36660	COG0175	sulfate reduction
YIM_RS36670	COG0529	Catalyzes the synthesis of activated sulfate
YIM_RS36675	COG1063	alcohol dehydrogenase
YIM_RS36685	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
YIM_RS36705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
YIM_RS36715	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS36720	COG2814	Major facilitator Superfamily
YIM_RS36725	COG3507	Belongs to the glycosyl hydrolase 43 family
YIM_RS36730	COG3250	beta-galactosidase activity
YIM_RS36750	COG1472	Belongs to the glycosyl hydrolase 3 family
YIM_RS36755	COG3250	beta-galactosidase activity
YIM_RS36760	COG2814	Major facilitator Superfamily
YIM_RS36765	COG2723	6-phospho-beta-galactosidase activity
YIM_RS36830	COG3903	Transcriptional regulator
YIM_RS36830	COG3629	intracellular signal transduction
YIM_RS36895	COG0210	DNA helicase
YIM_RS36900	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
YIM_RS36925	COG1131	(ABC) transporter
YIM_RS36960	COG0395	ABC-type sugar transport system, permease component
YIM_RS37040	COG1454	alcohol dehydrogenase
YIM_RS37115	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
YIM_RS37155	COG2226	methyltransferase
YIM_RS37170	COG1846	Transcriptional regulator
YIM_RS37195	COG1078	dGTPase activity
YIM_RS37210	COG1120	ATPase activity
YIM_RS37215	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YIM_RS37220	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
YIM_RS37220	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
YIM_RS37235	COG3795	YCII-related domain
YIM_RS37240	COG4941	Belongs to the sigma-70 factor family
YIM_RS37255	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
YIM_RS37270	COG1842	Phage shock protein A
YIM_RS37275	COG0477	Major facilitator Superfamily
YIM_RS37305	COG2072	flavoprotein involved in K transport
YIM_RS37335	COG1802	Transcriptional regulator
YIM_RS37340	COG1804	L-carnitine dehydratase bile acid-inducible protein F
YIM_RS37370	COG1309	transcriptional regulator
YIM_RS37380	COG0137	argininosuccinate synthase activity
YIM_RS37405	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
YIM_RS37435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YIM_RS37450	COG3903	Transcriptional regulator
YIM_RS37450	COG3629	intracellular signal transduction
YIM_RS37475	COG1132	(ABC) transporter
YIM_RS37485	COG4585	Histidine kinase
YIM_RS37505	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS37510	COG1846	Transcriptional regulator
YIM_RS37555	COG2271	Major facilitator Superfamily
YIM_RS37560	COG4948	Mandelate Racemase Muconate Lactonizing
YIM_RS37565	COG0800	Aldolase
YIM_RS37575	COG1414	Transcriptional regulator
YIM_RS37615	COG0640	Transcriptional regulator
YIM_RS37655	COG0659	secondary active sulfate transmembrane transporter activity
YIM_RS37670	COG1609	Transcriptional regulator
YIM_RS37675	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
YIM_RS37690	COG3693	PFAM glycoside hydrolase, family 10
YIM_RS37705	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
YIM_RS37725	COG0477	Major facilitator Superfamily
YIM_RS37750	COG5310	Homospermidine synthase
YIM_RS37805	COG4106	trans-aconitate 2-methyltransferase activity
YIM_RS37815	COG0358	DNA primase activity
YIM_RS37820	COG1595	DNA-templated transcription, initiation
YIM_RS37825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YIM_RS37830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YIM_RS37835	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YIM_RS37870	COG2197	response regulator
YIM_RS37875	COG4585	Histidine kinase
YIM_RS37885	COG1131	(ABC) transporter
YIM_RS37890	COG0423	glycine-tRNA ligase activity
YIM_RS37935	COG0701	Predicted permease
YIM_RS37945	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
YIM_RS37950	COG1381	Involved in DNA repair and RecF pathway recombination
YIM_RS37985	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
YIM_RS37990	COG3629	intracellular signal transduction
YIM_RS37990	COG3903	Transcriptional regulator
YIM_RS38005	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
YIM_RS38015	COG0537	adenosine 5'-monophosphoramidase activity
YIM_RS38025	COG0484	heat shock protein binding
YIM_RS38040	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
YIM_RS38055	COG1953	Uracil, thiamine, allantoin
YIM_RS38065	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
YIM_RS38105	COG0640	Transcriptional regulator
YIM_RS38125	COG2409	Drug exporters of the RND superfamily
YIM_RS38135	COG2197	response regulator
YIM_RS38180	COG1024	Enoyl-CoA hydratase
YIM_RS38185	COG2732	(Barnase) inhibitor
YIM_RS38200	COG0604	alcohol dehydrogenase
YIM_RS38205	COG2267	carboxylic ester hydrolase activity
YIM_RS38210	COG0531	amino acid
YIM_RS38215	COG2070	2-Nitropropane dioxygenase
YIM_RS38240	COG0481	GTPase activity
YIM_RS38280	COG0268	Binds directly to 16S ribosomal RNA
YIM_RS38305	COG1555	photosystem II stabilization
YIM_RS38305	COG1596	polysaccharide export
YIM_RS38330	COG1307	EDD domain protein, DegV family
YIM_RS38335	COG2755	lipolytic protein G-D-S-L family
YIM_RS38340	COG0406	alpha-ribazole phosphatase activity
YIM_RS38345	COG0799	negative regulation of ribosome biogenesis
YIM_RS38350	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
YIM_RS38355	COG0514	ATP-dependent DNA helicase (RecQ)
YIM_RS38360	COG0477	Major facilitator Superfamily
YIM_RS38370	COG1309	transcriptional regulator
YIM_RS38380	COG0577	efflux transmembrane transporter activity
YIM_RS38380	COG1136	(ABC) transporter
YIM_RS38390	COG2197	response regulator
YIM_RS38405	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
YIM_RS38410	COG0211	Belongs to the bacterial ribosomal protein bL27 family
YIM_RS38415	COG0261	This protein binds to 23S rRNA in the presence of protein L20
YIM_RS38420	COG1530	ribonuclease E activity
YIM_RS38420	COG1530	ribonuclease E activity
YIM_RS38430	COG0842	Transport permease protein
YIM_RS38440	COG1131	(ABC) transporter
YIM_RS38455	COG2186	Transcriptional regulator
YIM_RS38465	COG0105	UTP biosynthetic process
YIM_RS38475	COG2366	antibiotic biosynthetic process
YIM_RS38490	COG0285	dihydrofolate synthase activity
YIM_RS38515	COG1082	Xylose isomerase domain protein TIM barrel
YIM_RS38530	COG1172	Belongs to the binding-protein-dependent transport system permease family
YIM_RS38535	COG1129	ABC transporter
YIM_RS38545	COG2755	lipolytic protein G-D-S-L family
YIM_RS38550	COG2755	lipolytic protein G-D-S-L family
YIM_RS38560	COG0525	valine-tRNA ligase activity
YIM_RS38595	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
YIM_RS38615	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
YIM_RS38620	COG0740	serine-type endopeptidase activity
YIM_RS38630	COG0544	peptidyl-prolyl cis-trans isomerase activity
YIM_RS38690	COG0018	arginyl-trna synthetase
YIM_RS38735	COG1674	ftsk spoiiie
YIM_RS38810	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
YIM_RS38845	COG0477	Major facilitator Superfamily
YIM_RS38850	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
YIM_RS38860	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
YIM_RS38880	COG0668	transmembrane transport
YIM_RS38890	COG0366	Alpha amylase catalytic
YIM_RS38920	COG2902	Dehydrogenase
YIM_RS38935	COG0629	single-stranded DNA binding
YIM_RS39035	COG2755	lipolytic protein G-D-S-L family
YIM_RS39035	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
YIM_RS39055	COG1695	Transcriptional regulator
YIM_RS39070	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
YIM_RS39080	COG0583	DNA-binding transcription factor activity
YIM_RS39085	COG5006	permease, DMT superfamily
YIM_RS39095	COG1846	Transcriptional regulator
YIM_RS39130	COG0640	Transcriptional regulator
YIM_RS39145	COG2226	methyltransferase
YIM_RS39150	COG0492	ferredoxin-NADP+ reductase activity
YIM_RS39170	COG0318	PFAM AMP-dependent synthetase and ligase
YIM_RS39195	COG2197	response regulator
YIM_RS39225	COG0326	Molecular chaperone. Has ATPase activity
YIM_RS39235	COG3467	pyridoxamine 5'-phosphate
YIM_RS39240	COG2084	Dehydrogenase
YIM_RS39280	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
YIM_RS39285	COG3321	synthase
YIM_RS39285	COG0604	alcohol dehydrogenase
YIM_RS39380	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YIM_RS39395	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
YIM_RS39425	COG0604	alcohol dehydrogenase
YIM_RS39425	COG3321	synthase
YIM_RS39425	COG0604	alcohol dehydrogenase
YIM_RS39425	COG3321	synthase
YIM_RS39455	COG0477	Major facilitator Superfamily
YIM_RS39460	COG2226	methyltransferase
YIM_RS39485	COG1793	dna ligase
YIM_RS39495	COG2814	Major facilitator Superfamily
YIM_RS39500	COG0656	L-ascorbic acid biosynthetic process
YIM_RS39505	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS39510	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS39530	COG0583	DNA-binding transcription factor activity
YIM_RS39535	COG0667	Aldo Keto reductase
YIM_RS39545	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
YIM_RS39545	COG1672	PFAM Archaeal ATPase
YIM_RS39580	COG0531	amino acid
YIM_RS39585	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YIM_RS39635	COG0246	Mannitol dehydrogenase
YIM_RS39665	COG2197	response regulator
YIM_RS39685	COG3254	rhamnose metabolic process
YIM_RS39690	COG2186	Transcriptional regulator
YIM_RS39695	COG1172	Belongs to the binding-protein-dependent transport system permease family
YIM_RS39700	COG1129	ABC transporter
YIM_RS39710	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS39715	COG4948	Mandelate Racemase Muconate Lactonizing
YIM_RS39720	COG0179	Fumarylacetoacetate (FAA) hydrolase
YIM_RS39740	COG3268	Saccharopine dehydrogenase
YIM_RS39745	COG2072	flavoprotein involved in K transport
YIM_RS39755	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
YIM_RS39755	COG1796	DNA polymerase
YIM_RS39770	COG0366	Alpha amylase catalytic
YIM_RS39775	COG0395	ABC-type sugar transport system, permease component
YIM_RS39780	COG1175	transmembrane transport
YIM_RS39790	COG1609	Transcriptional regulator
YIM_RS39815	COG2072	flavoprotein involved in K transport
YIM_RS39835	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
YIM_RS39840	COG0583	DNA-binding transcription factor activity
YIM_RS39865	COG0596	Alpha beta hydrolase
YIM_RS39870	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YIM_RS39900	COG3483	tryptophan 2,3-dioxygenase activity
YIM_RS39930	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS39935	COG1024	Enoyl-CoA hydratase
YIM_RS39945	COG1960	acyl-CoA dehydrogenase activity
YIM_RS39960	COG0583	DNA-binding transcription factor activity
YIM_RS39965	COG0471	metal ion transport
YIM_RS39970	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
YIM_RS39970	COG0235	Class ii aldolase
YIM_RS39985	COG0247	lactate metabolic process
YIM_RS39985	COG0277	FAD linked oxidase domain protein
YIM_RS39995	COG0067	glutamate synthase
YIM_RS39995	COG0069	glutamate synthase activity
YIM_RS39995	COG0070	glutamate synthase
YIM_RS40005	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS40020	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YIM_RS40025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YIM_RS40030	COG1132	(ABC) transporter
YIM_RS40035	COG1132	(ABC) transporter
YIM_RS40040	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
YIM_RS40055	COG3486	L-lysine 6-monooxygenase (NADPH) activity
YIM_RS40060	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
YIM_RS40065	COG1278	Cold shock
YIM_RS40070	COG3540	Alkaline phosphatase
YIM_RS40075	COG4991	sh3 domain protein
YIM_RS40080	COG3629	intracellular signal transduction
YIM_RS40080	COG3903	Transcriptional regulator
YIM_RS40085	COG4991	sh3 domain protein
YIM_RS40110	COG0300	oxidoreductase activity
YIM_RS40150	COG3321	synthase
YIM_RS40150	COG0604	alcohol dehydrogenase
YIM_RS40205	COG0577	efflux transmembrane transporter activity
YIM_RS40210	COG1136	(ABC) transporter
YIM_RS40210	COG0577	efflux transmembrane transporter activity
YIM_RS40230	COG0642	Histidine kinase
YIM_RS40235	COG0745	RESPONSE REGULATOR receiver
YIM_RS40240	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
YIM_RS40275	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
YIM_RS40290	COG1522	sequence-specific DNA binding
YIM_RS40295	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
YIM_RS40315	COG4715	Zinc finger, swim domain protein
YIM_RS40320	COG3552	Protein containing von Willebrand factor type A (VWA) domain
YIM_RS40325	COG2425	protein containing a von Willebrand factor type A (vWA) domain
YIM_RS40330	COG0714	Associated with various cellular activities
YIM_RS40335	COG3831	ATPase activity
YIM_RS40360	COG0515	serine threonine protein kinase
YIM_RS40360	COG2815	serine threonine protein kinase
YIM_RS40375	COG0714	Associated with various cellular activities
YIM_RS40385	COG2205	protein histidine kinase activity
YIM_RS40395	COG3903	Transcriptional regulator
YIM_RS40395	COG3629	intracellular signal transduction
YIM_RS40405	COG0745	RESPONSE REGULATOR receiver
YIM_RS40435	COG0175	sulfate reduction
YIM_RS40455	COG0583	DNA-binding transcription factor activity
YIM_RS40465	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
YIM_RS40470	COG0187	DNA topoisomerase II activity
YIM_RS40495	COG0515	serine threonine protein kinase
YIM_RS40510	COG3012	SEC-C Motif Domain Protein
YIM_RS40555	COG0640	Transcriptional regulator
YIM_RS40585	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
YIM_RS40665	COG0367	asparagine synthase
YIM_RS40680	COG1794	racemase activity, acting on amino acids and derivatives
YIM_RS40690	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS40695	COG1960	acyl-CoA dehydrogenase activity
YIM_RS40700	COG0318	PFAM AMP-dependent synthetase and ligase
YIM_RS40705	COG1960	acyl-CoA dehydrogenase activity
YIM_RS40760	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
YIM_RS40765	COG1960	acyl-CoA dehydrogenase activity
YIM_RS40775	COG0477	Major facilitator Superfamily
YIM_RS40795	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
YIM_RS40830	COG2124	cytochrome p450
YIM_RS40855	COG1917	Cupin 2, conserved barrel domain protein
YIM_RS40855	COG4977	sequence-specific DNA binding
YIM_RS40865	COG2197	response regulator
YIM_RS40870	COG4585	Histidine kinase
YIM_RS40890	COG3629	intracellular signal transduction
YIM_RS40895	COG1733	regulation of RNA biosynthetic process
YIM_RS40900	COG1045	serine acetyltransferase
YIM_RS40905	COG0367	asparagine synthase
YIM_RS40910	COG0523	cobalamin synthesis protein
YIM_RS40915	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
YIM_RS40930	COG5002	protein histidine kinase activity
YIM_RS40990	COG0640	Transcriptional regulator
YIM_RS40995	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS41000	COG0235	Class ii aldolase
YIM_RS41010	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
YIM_RS41015	COG0698	ribose 5-phosphate isomerase
YIM_RS41020	COG2376	Dihydroxyacetone kinase
YIM_RS41025	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YIM_RS41030	COG0588	phosphoglycerate mutase activity
YIM_RS41035	COG1349	DNA-binding transcription factor activity
YIM_RS41040	COG2814	Major facilitator Superfamily
YIM_RS41045	COG1070	Carbohydrate kinase
YIM_RS41065	COG3655	Transcriptional regulator
YIM_RS41070	COG1733	regulation of RNA biosynthetic process
YIM_RS41080	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
YIM_RS41100	COG1295	ribonuclease BN
YIM_RS41105	COG2272	Belongs to the type-B carboxylesterase lipase family
YIM_RS41110	COG1309	transcriptional regulator
YIM_RS41140	COG2223	nitrite transmembrane transporter activity
YIM_RS41150	COG0635	Involved in the biosynthesis of porphyrin-containing compound
YIM_RS41155	COG1609	Transcriptional regulator
YIM_RS41175	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
YIM_RS41180	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
YIM_RS41205	COG1959	2 iron, 2 sulfur cluster binding
YIM_RS41220	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
YIM_RS41230	COG2197	response regulator
YIM_RS41235	COG4585	Histidine kinase
YIM_RS41250	COG1309	transcriptional regulator
YIM_RS41260	COG0587	DNA-directed DNA polymerase activity
YIM_RS41270	COG1309	transcriptional regulator
YIM_RS41300	COG2261	transglycosylase associated protein
YIM_RS41310	COG0640	Transcriptional regulator
YIM_RS41345	COG2186	Transcriptional regulator
YIM_RS41355	COG2201	protein-glutamate methylesterase activity
YIM_RS41405	COG1733	regulation of RNA biosynthetic process
YIM_RS41430	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
YIM_RS41435	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
YIM_RS41445	COG1234	tRNA 3'-trailer cleavage
YIM_RS41450	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
YIM_RS41460	COG0823	Involved in the tonB-independent uptake of proteins
YIM_RS41465	COG0705	Rhomboid family
YIM_RS41470	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
YIM_RS41485	COG0583	DNA-binding transcription factor activity
YIM_RS41515	COG3191	aminopeptidase activity
YIM_RS41525	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
YIM_RS41530	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
YIM_RS41535	COG1335	isochorismatase
YIM_RS41575	COG3830	Belongs to the UPF0237 family
YIM_RS41575	COG0560	Phosphoserine phosphatase
YIM_RS41580	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
YIM_RS41585	COG2318	DinB family
YIM_RS41595	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
YIM_RS41595	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
YIM_RS41600	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
YIM_RS41620	COG1012	belongs to the aldehyde dehydrogenase family
YIM_RS41625	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
YIM_RS41630	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
YIM_RS41700	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
YIM_RS41725	COG2197	response regulator
YIM_RS41730	COG3265	gluconokinase activity
YIM_RS41735	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
YIM_RS41755	COG1609	Transcriptional regulator
YIM_RS41780	COG3509	depolymerase
YIM_RS41795	COG2197	response regulator
YIM_RS41810	COG1595	DNA-templated transcription, initiation
YIM_RS41820	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
YIM_RS41845	COG0612	Peptidase, M16
YIM_RS41880	COG0714	Associated with various cellular activities
YIM_RS41910	COG1309	transcriptional regulator
YIM_RS41925	COG0210	DNA helicase
YIM_RS41930	COG0210	DNA helicase
YIM_RS41950	COG2378	regulation of single-species biofilm formation
YIM_RS41985	COG0148	phosphopyruvate hydratase activity
YIM_RS41990	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
YIM_RS41990	COG2146	nitrite reductase [NAD(P)H] activity
YIM_RS41995	COG2146	nitrite reductase [NAD(P)H] activity
YIM_RS41995	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
YIM_RS42005	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
YIM_RS42010	COG0243	molybdopterin cofactor binding
YIM_RS42030	COG2267	carboxylic ester hydrolase activity
YIM_RS42040	COG2267	carboxylic ester hydrolase activity
YIM_RS42075	COG0513	Belongs to the DEAD box helicase family
YIM_RS42100	COG2095	MarC family integral membrane protein
YIM_RS42105	COG0613	PHP domain protein
YIM_RS42135	COG0598	Magnesium transport protein CorA
YIM_RS42190	COG0330	HflC and HflK could
YIM_RS42195	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
YIM_RS42200	COG2239	Acts as a magnesium transporter
YIM_RS42215	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
YIM_RS42220	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YIM_RS42235	COG4122	O-methyltransferase activity
YIM_RS42240	COG2814	Major facilitator Superfamily
YIM_RS42245	COG0583	DNA-binding transcription factor activity
YIM_RS42250	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
YIM_RS42260	COG1024	Enoyl-CoA hydratase
YIM_RS42265	COG0519	Catalyzes the synthesis of GMP from XMP
YIM_RS42290	COG1271	oxidase subunit
YIM_RS42300	COG4988	ABC transporter
YIM_RS42310	COG0463	Glycosyl transferase, family 2
YIM_RS42325	COG1611	Belongs to the LOG family
YIM_RS42380	COG0391	Required for morphogenesis under gluconeogenic growth conditions
YIM_RS42385	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
YIM_RS42385	COG0778	Nitroreductase
YIM_RS42400	COG1725	Transcriptional regulator
YIM_RS42435	COG0438	transferase activity, transferring glycosyl groups
YIM_RS42465	COG1316	TRANSCRIPTIONal
YIM_RS42470	COG1316	TRANSCRIPTIONal
YIM_RS42480	COG2259	Doxx family
YIM_RS42510	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
YIM_RS42520	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
YIM_RS42520	COG5479	isomerase activity
YIM_RS42525	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
YIM_RS42535	COG0318	PFAM AMP-dependent synthetase and ligase
YIM_RS42540	COG2814	Major facilitator Superfamily
YIM_RS42545	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
YIM_RS42560	COG1960	acyl-CoA dehydrogenase activity
YIM_RS42565	COG0318	PFAM AMP-dependent synthetase and ligase
YIM_RS42615	COG2205	protein histidine kinase activity
YIM_RS42620	COG0745	RESPONSE REGULATOR receiver
YIM_RS42625	COG0483	inositol monophosphate 1-phosphatase activity
YIM_RS42665	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
YIM_RS42665	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
YIM_RS42670	COG1388	LysM domain
YIM_RS42670	COG3103	Sh3 type 3 domain protein
YIM_RS42670	COG0791	NLP P60 protein
YIM_RS42695	COG1725	Transcriptional regulator
YIM_RS42715	COG0596	Alpha beta hydrolase
YIM_RS42735	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
YIM_RS42760	COG0424	maF-like protein
YIM_RS42765	COG1301	dicarboxylic acid transport
YIM_RS42785	COG3845	ABC transporter
YIM_RS42790	COG1079	Belongs to the binding-protein-dependent transport system permease family
YIM_RS42795	COG1079	Belongs to the binding-protein-dependent transport system permease family
YIM_RS42810	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
YIM_RS42815	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
YIM_RS42820	COG0235	Class ii aldolase
YIM_RS42825	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
YIM_RS42830	COG4770	biotin carboxylase activity
YIM_RS42845	COG2197	response regulator
YIM_RS42855	COG0318	PFAM AMP-dependent synthetase and ligase
YIM_RS42860	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
YIM_RS42865	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
YIM_RS42870	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
YIM_RS42890	COG1473	amidohydrolase
YIM_RS42890	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
YIM_RS42915	COG0515	serine threonine protein kinase
YIM_RS42930	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
YIM_RS42935	COG0706	membrane insertase activity
YIM_RS42965	COG3973	AAA domain
YIM_RS42980	COG0477	Major facilitator Superfamily
YIM_RS42990	COG0667	Aldo Keto reductase
YIM_RS42995	COG0667	Aldo Keto reductase
YIM_RS43000	COG0789	Transcriptional regulator
YIM_RS43020	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
YIM_RS43025	COG1012	belongs to the aldehyde dehydrogenase family
YIM_RS43030	COG1012	belongs to the aldehyde dehydrogenase family
YIM_RS43075	COG2271	Major facilitator Superfamily
YIM_RS43080	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
YIM_RS43100	COG1079	Belongs to the binding-protein-dependent transport system permease family
YIM_RS43105	COG4603	Belongs to the binding-protein-dependent transport system permease family
YIM_RS43110	COG3845	ABC transporter
YIM_RS43115	COG1744	ABC transporter substrate-binding protein PnrA-like
YIM_RS43120	COG1082	Xylose isomerase domain protein TIM barrel
YIM_RS43125	COG3345	alpha-galactosidase
YIM_RS43140	COG2009	succinate dehydrogenase
YIM_RS43155	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
YIM_RS43205	COG1686	Belongs to the peptidase S11 family
YIM_RS43210	COG2814	Major facilitator Superfamily
YIM_RS43215	COG1295	ribonuclease BN
YIM_RS43235	COG0180	Tryptophanyl-tRNA synthetase
YIM_RS43245	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
YIM_RS43275	COG0708	Exodeoxyribonuclease III
YIM_RS43325	COG2814	Major facilitator Superfamily
YIM_RS43330	COG0640	Transcriptional regulator
YIM_RS43335	COG2814	Major facilitator Superfamily
YIM_RS43355	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
YIM_RS43380	COG1228	amidohydrolase
YIM_RS43395	COG0587	DNA-directed DNA polymerase activity
YIM_RS43430	COG0138	bifunctional purine biosynthesis protein purh
YIM_RS43455	COG0045	succinate-CoA ligase (ADP-forming) activity
YIM_RS43500	COG0515	serine threonine protein kinase
YIM_RS43505	COG2815	serine threonine protein kinase
YIM_RS43505	COG0515	serine threonine protein kinase
YIM_RS43510	COG0583	DNA-binding transcription factor activity
YIM_RS43520	COG2197	response regulator
YIM_RS43540	COG0518	GMP synthase (glutamine-hydrolyzing) activity
YIM_RS43540	COG0519	Catalyzes the synthesis of GMP from XMP
YIM_RS43550	COG1012	belongs to the aldehyde dehydrogenase family
YIM_RS43570	COG0516	GMP reductase activity
YIM_RS43625	COG1309	transcriptional regulator
YIM_RS43630	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS43635	COG0459	protein refolding
YIM_RS43640	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
YIM_RS43645	COG3540	Alkaline phosphatase
YIM_RS43655	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
YIM_RS43660	COG0456	acetyltransferase
YIM_RS43680	COG2186	Transcriptional regulator
YIM_RS43690	COG0318	PFAM AMP-dependent synthetase and ligase
YIM_RS43695	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
YIM_RS43695	COG0825	malonyl-CoA metabolic process
YIM_RS43700	COG0154	amidase activity
YIM_RS43705	COG3458	cephalosporin-C deacetylase activity
YIM_RS43710	COG0802	atpase or kinase
YIM_RS43720	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
YIM_RS43725	COG3842	ATPase activity
YIM_RS43730	COG1070	Carbohydrate kinase
YIM_RS43735	COG1063	alcohol dehydrogenase
YIM_RS43740	COG1349	DNA-binding transcription factor activity
YIM_RS43745	COG1063	alcohol dehydrogenase
YIM_RS43750	COG0395	ABC-type sugar transport system, permease component
YIM_RS43770	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
YIM_RS43800	COG0318	PFAM AMP-dependent synthetase and ligase
YIM_RS43820	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
YIM_RS43825	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
YIM_RS43830	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
YIM_RS43870	COG0443	Heat shock 70 kDa protein
YIM_RS43875	COG1674	ftsk spoiiie
YIM_RS43885	COG1404	Belongs to the peptidase S8 family
YIM_RS43925	COG0101	tRNA pseudouridine synthase activity
YIM_RS43930	COG0203	ribosomal protein L17
YIM_RS43935	COG0202	RNA polymerase activity
YIM_RS43940	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
YIM_RS43945	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
YIM_RS43960	COG0257	Belongs to the bacterial ribosomal protein bL36 family
YIM_RS43965	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
YIM_RS43975	COG0563	adenylate kinase activity
YIM_RS43985	COG1280	lysine exporter protein (LysE YggA)
YIM_RS43995	COG0200	Binds to the 23S rRNA
YIM_RS44000	COG1841	ribosomal large subunit assembly
YIM_RS44005	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
YIM_RS44010	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
YIM_RS44015	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
YIM_RS44020	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
YIM_RS44030	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
YIM_RS44035	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
YIM_RS44040	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
YIM_RS44045	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
YIM_RS44050	COG0255	Belongs to the universal ribosomal protein uL29 family
YIM_RS44055	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
YIM_RS44060	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
YIM_RS44065	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
YIM_RS44070	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
YIM_RS44075	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
YIM_RS44080	COG0089	rRNA binding
YIM_RS44085	COG0088	Forms part of the polypeptide exit tunnel
YIM_RS44090	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
YIM_RS44095	COG0051	transcription antitermination factor activity, RNA binding
YIM_RS44105	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
YIM_RS44110	COG0049	tRNA binding
YIM_RS44115	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
YIM_RS44145	COG0084	hydrolase, TatD family'
YIM_RS44155	COG0109	protoheme IX farnesyltransferase activity
YIM_RS44165	COG3507	Belongs to the glycosyl hydrolase 43 family
YIM_RS44170	COG0673	inositol 2-dehydrogenase activity
YIM_RS44180	COG1172	Belongs to the binding-protein-dependent transport system permease family
YIM_RS44185	COG1129	ABC transporter
YIM_RS44195	COG1940	carbohydrate kinase activity
YIM_RS44250	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
YIM_RS44255	COG2197	response regulator
YIM_RS44260	COG4585	Histidine kinase
YIM_RS44285	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
YIM_RS44335	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
YIM_RS44350	COG0222	ribosome binding
YIM_RS44355	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
YIM_RS44370	COG0081	regulation of translation
YIM_RS44395	COG0436	Aminotransferase
YIM_RS44405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YIM_RS44425	COG2030	dehydratase
YIM_RS44435	COG0267	Belongs to the bacterial ribosomal protein bL33 family
YIM_RS44465	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
YIM_RS44470	COG0586	Pfam SNARE associated Golgi protein
YIM_RS44475	COG4585	Histidine kinase
YIM_RS44480	COG2197	response regulator
YIM_RS44485	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
YIM_RS44495	COG1309	transcriptional regulator
YIM_RS44565	COG1660	Displays ATPase and GTPase activities
YIM_RS44605	COG0270	DNA (cytosine-5-)-methyltransferase activity
YIM_RS44635	COG1666	GTP binding
YIM_RS44645	COG1309	transcriptional regulator
YIM_RS44650	COG0596	Alpha beta hydrolase
YIM_RS44655	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
YIM_RS44680	COG0673	inositol 2-dehydrogenase activity
YIM_RS44690	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
YIM_RS44690	COG2146	nitrite reductase [NAD(P)H] activity
YIM_RS44700	COG0438	transferase activity, transferring glycosyl groups
YIM_RS44705	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
YIM_RS44720	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
YIM_RS44765	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
YIM_RS44795	COG1215	transferase activity, transferring glycosyl groups
YIM_RS44800	COG1834	amidinotransferase
YIM_RS44805	COG1522	sequence-specific DNA binding
YIM_RS44815	COG0674	pyruvate-flavodoxin oxidoreductase activity
YIM_RS44815	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
YIM_RS44820	COG1013	pyruvate-flavodoxin oxidoreductase activity
YIM_RS44830	COG0142	geranyltranstransferase activity
YIM_RS44885	COG1007	ATP synthesis coupled electron transport
YIM_RS44900	COG0713	ATP synthesis coupled electron transport
YIM_RS44905	COG0839	Belongs to the complex I subunit 6 family
YIM_RS44910	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YIM_RS44915	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
YIM_RS44920	COG1034	ATP synthesis coupled electron transport
YIM_RS44935	COG0649	NAD binding
YIM_RS44940	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YIM_RS44945	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YIM_RS44960	COG2226	methyltransferase
YIM_RS44965	COG0438	transferase activity, transferring glycosyl groups
YIM_RS44975	COG0483	inositol monophosphate 1-phosphatase activity
YIM_RS44990	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
YIM_RS44995	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
YIM_RS45000	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
YIM_RS45020	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
YIM_RS45030	COG1522	sequence-specific DNA binding
YIM_RS45050	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YIM_RS45070	COG0406	alpha-ribazole phosphatase activity
YIM_RS45075	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
YIM_RS45085	COG1136	(ABC) transporter
YIM_RS45085	COG0577	efflux transmembrane transporter activity
YIM_RS45090	COG0577	efflux transmembrane transporter activity
YIM_RS45090	COG1136	(ABC) transporter
YIM_RS45095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YIM_RS45120	COG1648	precorrin-2 dehydrogenase activity
YIM_RS45120	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
YIM_RS45125	COG0181	hydroxymethylbilane synthase activity
YIM_RS45130	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
YIM_RS45135	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
YIM_RS45140	COG3629	intracellular signal transduction
YIM_RS45140	COG3903	Transcriptional regulator
YIM_RS45175	COG0318	PFAM AMP-dependent synthetase and ligase
YIM_RS45180	COG1595	DNA-templated transcription, initiation
YIM_RS45195	COG0204	Acyl-transferase
YIM_RS45215	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
YIM_RS45225	COG0506	proline dehydrogenase activity
YIM_RS45250	COG5002	protein histidine kinase activity
YIM_RS45255	COG0667	Aldo Keto reductase
YIM_RS45290	COG0438	transferase activity, transferring glycosyl groups
YIM_RS45305	COG0812	UDP-N-acetylmuramate dehydrogenase activity
YIM_RS45325	COG0788	formyltetrahydrofolate deformylase activity
YIM_RS45335	COG2130	NADP-dependent
YIM_RS45350	COG1174	glycine betaine transport
YIM_RS45355	COG1174	glycine betaine transport
YIM_RS45360	COG2986	histidine ammonia-lyase
YIM_RS45390	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
YIM_RS45395	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
YIM_RS45395	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
YIM_RS45415	COG4941	Belongs to the sigma-70 factor family
YIM_RS45420	COG3795	YCII-related domain
YIM_RS45430	COG2733	membrane
YIM_RS45450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YIM_RS45455	COG2364	Membrane
YIM_RS45525	COG1027	Aspartate ammonia-lyase
YIM_RS45560	COG1674	ftsk spoiiie
YIM_RS45580	COG2188	Transcriptional regulator
YIM_RS45585	COG0546	phosphoglycolate phosphatase activity
YIM_RS45620	COG1278	Cold shock
YIM_RS45635	COG1595	DNA-templated transcription, initiation
YIM_RS45645	COG0477	Major facilitator Superfamily
YIM_RS45655	COG1408	metallophosphoesterase
YIM_RS45660	COG0515	serine threonine protein kinase
YIM_RS45670	COG1012	belongs to the aldehyde dehydrogenase family
YIM_RS45675	COG4948	Mandelate Racemase Muconate Lactonizing
YIM_RS45680	COG1414	Transcriptional regulator
YIM_RS45685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YIM_RS45695	COG2197	response regulator
YIM_RS45700	COG4585	Histidine kinase
YIM_RS45725	COG1132	(ABC) transporter
YIM_RS45730	COG1132	(ABC) transporter
YIM_RS45740	COG0515	serine threonine protein kinase
YIM_RS45745	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
YIM_RS45790	COG0443	Heat shock 70 kDa protein
YIM_RS45845	COG1309	transcriptional regulator
YIM_RS45850	COG1064	alcohol dehydrogenase
YIM_RS45865	COG1309	transcriptional regulator
YIM_RS45875	COG0640	Transcriptional regulator
YIM_RS45890	COG2272	Belongs to the type-B carboxylesterase lipase family
YIM_RS45930	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS45975	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YIM_RS46020	COG1316	TRANSCRIPTIONal
YIM_RS46040	COG0204	Acyl-transferase
YIM_RS46040	COG0318	PFAM AMP-dependent synthetase and ligase
YIM_RS46065	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
YIM_RS46080	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
YIM_RS46085	COG0456	acetyltransferase
YIM_RS46085	COG0454	-acetyltransferase
YIM_RS46090	COG0745	RESPONSE REGULATOR receiver
YIM_RS46100	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
YIM_RS46120	COG4044	May play a role in the intracellular transport of hydrophobic ligands
YIM_RS46125	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
YIM_RS46130	COG1984	allophanate hydrolase subunit 2
YIM_RS46140	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
YIM_RS46180	COG3845	ABC transporter
YIM_RS46225	COG3181	Tripartite tricarboxylate transporter family receptor
YIM_RS46230	COG3290	protein histidine kinase activity
YIM_RS46235	COG4565	transcriptional regulatory protein
YIM_RS46250	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
YIM_RS46325	COG1132	(ABC) transporter
YIM_RS46330	COG1132	(ABC) transporter
YIM_RS46335	COG0047	phosphoribosylformylglycinamidine synthase activity
YIM_RS46340	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
YIM_RS46380	COG0730	response to heat
YIM_RS46390	COG1126	abc transporter atp-binding protein
YIM_RS46395	COG0765	amino acid transport
YIM_RS46400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YIM_RS46410	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
YIM_RS46455	COG0436	Aminotransferase
YIM_RS46460	COG1376	ErfK ybiS ycfS ynhG family protein
YIM_RS46465	COG3953	SLT domain
YIM_RS46465	COG5280	Phage tail tape measure protein TP901
YIM_RS46480	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YIM_RS46480	COG0515	serine threonine protein kinase
YIM_RS46525	COG0584	glycerophosphoryl diester phosphodiesterase
YIM_RS46530	COG2814	Major facilitator Superfamily
YIM_RS46540	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
YIM_RS46580	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
YIM_RS46615	COG0586	Pfam SNARE associated Golgi protein
YIM_RS46620	COG0277	FAD linked oxidase domain protein
YIM_RS46635	COG0477	Major facilitator Superfamily
YIM_RS46655	COG2353	YceI-like domain
YIM_RS46660	COG0586	Pfam SNARE associated Golgi protein
YIM_RS46670	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
YIM_RS46675	COG2188	Transcriptional regulator
YIM_RS46680	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS46685	COG1072	(Pantothenic acid kinase))
YIM_RS46725	COG0243	molybdopterin cofactor binding
YIM_RS46730	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YIM_RS46750	COG0300	oxidoreductase activity
YIM_RS46760	COG0542	response to heat
YIM_RS46780	COG0789	Transcriptional regulator
YIM_RS46785	COG0484	heat shock protein binding
YIM_RS46790	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
YIM_RS46795	COG0443	Heat shock 70 kDa protein
YIM_RS46835	COG2181	nitrate reductase activity
YIM_RS46835	COG0247	lactate metabolic process
YIM_RS46840	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YIM_RS46850	COG1522	sequence-specific DNA binding
YIM_RS46870	COG1309	transcriptional regulator
YIM_RS46875	COG1960	acyl-CoA dehydrogenase activity
YIM_RS46885	COG2340	Cysteine-rich secretory protein family
YIM_RS46935	COG0737	Belongs to the 5'-nucleotidase family
YIM_RS46935	COG1525	nuclease
YIM_RS46935	COG4085	toxin activity
YIM_RS46955	COG3663	DNA glycosylase
YIM_RS46960	COG2197	response regulator
YIM_RS46965	COG1960	acyl-CoA dehydrogenase activity
YIM_RS46990	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
YIM_RS46995	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
YIM_RS47015	COG0765	amino acid transport
YIM_RS47035	COG1305	Transglutaminase-like
YIM_RS47045	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
YIM_RS47055	COG0022	dehydrogenase e1 component
YIM_RS47060	COG0508	dehydrogenase complex catalyzes the overall conversion of
YIM_RS47075	COG1132	(ABC) transporter
YIM_RS47085	COG3030	protein affecting phage T7 exclusion by the F plasmid
YIM_RS47100	COG1309	transcriptional regulator
YIM_RS47105	COG2030	dehydratase
YIM_RS47110	COG1028	Short-chain dehydrogenase reductase Sdr
YIM_RS47115	COG0183	Belongs to the thiolase family
YIM_RS47125	COG0584	glycerophosphoryl diester phosphodiesterase
YIM_RS47135	COG0789	Transcriptional regulator
YIM_RS47145	COG0456	acetyltransferase
YIM_RS47145	COG1846	Transcriptional regulator
YIM_RS47205	COG4133	protoheme IX ABC transporter activity
YIM_RS47210	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
YIM_RS47230	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
YIM_RS47250	COG4585	Histidine kinase
YIM_RS47255	COG2197	response regulator
YIM_RS47275	COG0220	tRNA (guanine-N7-)-methyltransferase activity
YIM_RS47285	COG1136	(ABC) transporter
YIM_RS47295	COG2197	response regulator
YIM_RS47300	COG0402	S-adenosylhomocysteine deaminase activity
YIM_RS47315	COG2197	response regulator
YIM_RS47320	COG4585	Histidine kinase
YIM_RS47330	COG4221	oxidoreductase activity
YIM_RS47350	COG0842	Transport permease protein
YIM_RS47365	COG2814	Major facilitator Superfamily
YIM_RS47590	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
YIM_RS47595	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
YIM_RS47640	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YIM_RS47645	COG1309	transcriptional regulator
YIM_RS47675	COG1695	Transcriptional regulator
YIM_RS47685	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
YIM_RS47690	COG1228	amidohydrolase
YIM_RS47695	COG0673	inositol 2-dehydrogenase activity
YIM_RS47700	COG1940	carbohydrate kinase activity
YIM_RS47735	COG0360	Binds together with S18 to 16S ribosomal RNA
YIM_RS47745	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
YIM_RS47750	COG0359	binds to the 23S rRNA
YIM_RS47790	COG2267	carboxylic ester hydrolase activity
YIM_RS47830	COG3384	dioxygenase
YIM_RS47855	COG2197	response regulator
YIM_RS47870	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
YIM_RS47880	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YIM_RS47915	COG0495	leucyl-tRNA aminoacylation
YIM_RS47930	COG1678	Uncharacterized ACR, COG1678
YIM_RS47990	COG4585	Histidine kinase
YIM_RS48015	COG0765	amino acid transport
YIM_RS48020	COG0765	amino acid transport
YIM_RS48035	COG1595	DNA-templated transcription, initiation
YIM_RS48050	COG3118	belongs to the thioredoxin family
YIM_RS48050	COG0492	ferredoxin-NADP+ reductase activity
YIM_RS48055	COG3409	Peptidoglycan-binding domain 1 protein
YIM_RS48055	COG0860	N-Acetylmuramoyl-L-alanine amidase
YIM_RS48070	COG1181	Belongs to the D-alanine--D-alanine ligase family
YIM_RS48080	COG1192	Involved in chromosome partitioning
YIM_RS48085	COG0357	Ribosomal RNA small subunit methyltransferase G
YIM_RS48100	COG0706	membrane insertase activity
YIM_RS48105	COG0759	Could be involved in insertion of integral membrane proteins into the membrane