locus-tag	class	description
ANACY_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ANACY_RS00015	COG2076	Multidrug Resistance protein
ANACY_RS00025	COG0723	plastoquinol--plastocyanin reductase activity
ANACY_RS00065	COG1216	Glycosyl transferase, family 2
ANACY_RS00065	COG0463	Glycosyl transferase, family 2
ANACY_RS00075	COG1131	(ABC) transporter
ANACY_RS00085	COG0003	Pfam Anion-transporting ATPase
ANACY_RS00090	COG2203	Gaf domain
ANACY_RS00090	COG3706	GGDEF domain
ANACY_RS00090	COG4251	negative regulation of phosphorylation
ANACY_RS00090	COG5001	Diguanylate cyclase
ANACY_RS00095	COG0592	DNA-directed DNA polymerase activity
ANACY_RS00100	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
ANACY_RS00105	COG2211	Major facilitator Superfamily
ANACY_RS00110	COG0708	Exodeoxyribonuclease III
ANACY_RS00120	COG3118	belongs to the thioredoxin family
ANACY_RS00125	COG2264	protein methyltransferase activity
ANACY_RS00130	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ANACY_RS00140	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ANACY_RS00150	COG1850	ribulose-bisphosphate carboxylase activity
ANACY_RS00160	COG4451	ribulose bisphosphate carboxylase, small
ANACY_RS00210	COG1121	(ABC) transporter
ANACY_RS00215	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ANACY_RS00230	COG0659	secondary active sulfate transmembrane transporter activity
ANACY_RS00240	COG1271	oxidase subunit
ANACY_RS00245	COG1294	oxidase, subunit
ANACY_RS00285	COG0124	histidyl-tRNA synthetase
ANACY_RS00310	COG4208	sulfate ABC transporter
ANACY_RS00315	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ANACY_RS00320	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ANACY_RS00325	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ANACY_RS00330	COG0784	Response regulator, receiver
ANACY_RS00335	COG0121	glutamine amidotransferase
ANACY_RS00385	COG4231	catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates
ANACY_RS00420	COG0515	serine threonine protein kinase
ANACY_RS00420	COG1357	PFAM Pentapeptide repeats (8 copies)
ANACY_RS00455	COG0629	single-stranded DNA binding
ANACY_RS00460	COG2084	Dehydrogenase
ANACY_RS00470	COG1301	dicarboxylic acid transport
ANACY_RS00475	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ANACY_RS00480	COG0475	glutathione-regulated potassium exporter activity
ANACY_RS00480	COG0589	response to stress
ANACY_RS00485	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
ANACY_RS00490	COG0456	acetyltransferase
ANACY_RS00500	COG4771	TonB-dependent receptor
ANACY_RS00505	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
ANACY_RS00545	COG2217	Heavy metal translocating P-type atpase
ANACY_RS00570	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ANACY_RS00575	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ANACY_RS00580	COG0189	ligase activity
ANACY_RS00585	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ANACY_RS00635	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ANACY_RS00670	COG0006	proline dipeptidase activity
ANACY_RS00675	COG0384	phenazine biosynthesis protein PhzF
ANACY_RS00700	COG0612	Peptidase, M16
ANACY_RS00705	COG0612	Peptidase, M16
ANACY_RS00770	COG3000	fatty acid hydroxylase
ANACY_RS00770	COG0300	oxidoreductase activity
ANACY_RS00785	COG2066	Belongs to the glutaminase family
ANACY_RS00790	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ANACY_RS00795	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ANACY_RS00795	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ANACY_RS00800	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ANACY_RS00815	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ANACY_RS00880	COG0784	Response regulator, receiver
ANACY_RS00880	COG2205	protein histidine kinase activity
ANACY_RS00900	COG0800	Aldolase
ANACY_RS00915	COG5002	protein histidine kinase activity
ANACY_RS00915	COG0784	Response regulator, receiver
ANACY_RS00915	COG2205	protein histidine kinase activity
ANACY_RS01025	COG0443	Heat shock 70 kDa protein
ANACY_RS01030	COG4294	response to UV
ANACY_RS01040	COG1045	serine acetyltransferase
ANACY_RS01055	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ANACY_RS01060	COG5554	nitrogen fixation
ANACY_RS01090	COG3118	belongs to the thioredoxin family
ANACY_RS01110	COG3546	catalase activity
ANACY_RS01115	COG2261	transglycosylase associated protein
ANACY_RS01120	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ANACY_RS01125	COG5398	heme oxygenase
ANACY_RS01130	COG2205	protein histidine kinase activity
ANACY_RS01130	COG2202	Pas domain
ANACY_RS01150	COG5001	Diguanylate cyclase
ANACY_RS01150	COG1716	ATPase activity
ANACY_RS01155	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
ANACY_RS01165	COG0497	DNA recombination
ANACY_RS01180	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ANACY_RS01195	COG0442	prolyl-tRNA aminoacylation
ANACY_RS01205	COG3311	Transcriptional regulator
ANACY_RS01215	COG1063	alcohol dehydrogenase
ANACY_RS01220	COG0306	phosphate transporter
ANACY_RS01225	COG0697	spore germination
ANACY_RS01240	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ANACY_RS01245	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ANACY_RS01255	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ANACY_RS01260	COG0745	RESPONSE REGULATOR receiver
ANACY_RS01265	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ANACY_RS01270	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ANACY_RS01275	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ANACY_RS01280	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ANACY_RS01285	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ANACY_RS01290	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ANACY_RS01295	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ANACY_RS01320	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ANACY_RS01325	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ANACY_RS01330	COG0511	ligase activity, forming carbon-carbon bonds
ANACY_RS01340	COG2988	succinylglutamate desuccinylase activity
ANACY_RS01355	COG0438	transferase activity, transferring glycosyl groups
ANACY_RS01370	COG1132	(ABC) transporter
ANACY_RS01385	COG0489	protein tyrosine kinase activity
ANACY_RS01390	COG0438	transferase activity, transferring glycosyl groups
ANACY_RS01410	COG1216	Glycosyl transferase, family 2
ANACY_RS01425	COG1216	Glycosyl transferase, family 2
ANACY_RS01435	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ANACY_RS01440	COG0579	oxidoreductase
ANACY_RS01445	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ANACY_RS01460	COG4245	von Willebrand factor, type A
ANACY_RS01465	COG0784	Response regulator, receiver
ANACY_RS01470	COG3842	ATPase activity
ANACY_RS01475	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
ANACY_RS01485	COG2319	Wd-40 repeat
ANACY_RS01485	COG5635	Nacht domain
ANACY_RS01505	COG2226	methyltransferase
ANACY_RS01520	COG0438	transferase activity, transferring glycosyl groups
ANACY_RS01535	COG0438	transferase activity, transferring glycosyl groups
ANACY_RS01540	COG0438	transferase activity, transferring glycosyl groups
ANACY_RS01550	COG1160	GTP binding
ANACY_RS01570	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ANACY_RS01595	COG0745	RESPONSE REGULATOR receiver
ANACY_RS01610	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ANACY_RS01625	COG0133	tryptophan synthase activity
ANACY_RS01660	COG0701	Predicted permease
ANACY_RS01705	COG1028	Short-chain dehydrogenase reductase Sdr
ANACY_RS01710	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ANACY_RS01710	COG0072	phenylalanine-tRNA ligase activity
ANACY_RS01715	COG0110	maltose O-acetyltransferase activity
ANACY_RS01725	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ANACY_RS01735	COG0702	epimerase
ANACY_RS01740	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ANACY_RS01745	COG0745	RESPONSE REGULATOR receiver
ANACY_RS01760	COG3536	Protein conserved in bacteria
ANACY_RS01780	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ANACY_RS01805	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ANACY_RS01815	COG0483	inositol monophosphate 1-phosphatase activity
ANACY_RS01820	COG0484	heat shock protein binding
ANACY_RS01825	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ANACY_RS01830	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ANACY_RS01855	COG1672	PFAM Archaeal ATPase
ANACY_RS01855	COG2319	Wd-40 repeat
ANACY_RS01865	COG1595	DNA-templated transcription, initiation
ANACY_RS01885	COG2319	Wd-40 repeat
ANACY_RS01885	COG1672	PFAM Archaeal ATPase
ANACY_RS01900	COG1505	serine-type exopeptidase activity
ANACY_RS01905	COG0643	Histidine kinase
ANACY_RS01905	COG0784	Response regulator, receiver
ANACY_RS01905	COG0643	Histidine kinase
ANACY_RS01905	COG2198	Histidine kinase
ANACY_RS01905	COG0784	Response regulator, receiver
ANACY_RS01905	COG2198	Histidine kinase
ANACY_RS01925	COG0784	Response regulator, receiver
ANACY_RS01935	COG0037	tRNA processing
ANACY_RS01950	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ANACY_RS01975	COG0439	Biotin carboxylase
ANACY_RS01990	COG0515	serine threonine protein kinase
ANACY_RS02005	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ANACY_RS02020	COG0492	ferredoxin-NADP+ reductase activity
ANACY_RS02035	COG0233	cytoplasmic translational termination
ANACY_RS02040	COG0528	UMP kinase activity
ANACY_RS02045	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ANACY_RS02080	COG0170	dolichyl monophosphate biosynthetic process
ANACY_RS02085	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ANACY_RS02090	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
ANACY_RS02095	COG3937	granule-associated protein
ANACY_RS02100	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ANACY_RS02105	COG0631	protein serine/threonine phosphatase activity
ANACY_RS02125	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ANACY_RS02130	COG2205	protein histidine kinase activity
ANACY_RS02135	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
ANACY_RS02145	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ANACY_RS02150	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ANACY_RS02155	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ANACY_RS02160	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ANACY_RS02165	COG0456	acetyltransferase
ANACY_RS02200	COG2010	Cytochrome c
ANACY_RS02205	COG2010	Cytochrome c
ANACY_RS02225	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ANACY_RS02275	COG0556	nucleotide-excision repair
ANACY_RS02290	COG0390	transport system, permease component
ANACY_RS02310	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ANACY_RS02360	COG0583	DNA-binding transcription factor activity
ANACY_RS02365	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
ANACY_RS02370	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ANACY_RS02375	COG4451	ribulose bisphosphate carboxylase, small
ANACY_RS02375	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ANACY_RS02380	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
ANACY_RS02385	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
ANACY_RS02390	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
ANACY_RS02395	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ANACY_RS02400	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ANACY_RS02425	COG2274	protein secretion by the type I secretion system
ANACY_RS02470	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ANACY_RS02480	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ANACY_RS02495	COG2062	phosphohistidine phosphatase, SixA
ANACY_RS02500	COG0372	Belongs to the citrate synthase family
ANACY_RS02505	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ANACY_RS02510	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ANACY_RS02515	COG0839	Belongs to the complex I subunit 6 family
ANACY_RS02520	COG0713	ATP synthesis coupled electron transport
ANACY_RS02525	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ANACY_RS02540	COG5002	protein histidine kinase activity
ANACY_RS02545	COG0745	RESPONSE REGULATOR receiver
ANACY_RS02550	COG2226	methyltransferase
ANACY_RS02565	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ANACY_RS02580	COG0107	imidazoleglycerol-phosphate synthase activity
ANACY_RS02585	COG2255	four-way junction helicase activity
ANACY_RS02600	COG1819	glycosyl
ANACY_RS02625	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ANACY_RS02630	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ANACY_RS02640	COG0525	valine-tRNA ligase activity
ANACY_RS02650	COG0113	porphobilinogen synthase activity
ANACY_RS02675	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ANACY_RS02695	COG0438	transferase activity, transferring glycosyl groups
ANACY_RS02705	COG1293	RNA-binding protein homologous to eukaryotic snRNP
ANACY_RS02710	COG2890	protein-(glutamine-N5) methyltransferase activity
ANACY_RS02730	COG0454	-acetyltransferase
ANACY_RS02745	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ANACY_RS02765	COG0194	GDP metabolic process
ANACY_RS02770	COG2052	Domain of unknown function (DUF370)
ANACY_RS02800	COG0142	geranyltranstransferase activity
ANACY_RS02810	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ANACY_RS02825	COG0475	glutathione-regulated potassium exporter activity
ANACY_RS02835	COG0629	single-stranded DNA binding
ANACY_RS02840	COG1077	Cell shape determining protein MreB Mrl
ANACY_RS02855	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ANACY_RS02855	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ANACY_RS02880	COG1487	ribonuclease activity
ANACY_RS02890	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
ANACY_RS02900	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
ANACY_RS02925	COG2319	Wd-40 repeat
ANACY_RS02925	COG4249	Peptidase C14 caspase catalytic subunit p20
ANACY_RS02945	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
ANACY_RS02955	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
ANACY_RS02995	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ANACY_RS03000	COG1690	Belongs to the RtcB family
ANACY_RS03005	COG0697	spore germination
ANACY_RS03010	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ANACY_RS03020	COG2082	Precorrin-8x methylmutase
ANACY_RS03060	COG0745	RESPONSE REGULATOR receiver
ANACY_RS03065	COG1366	Belongs to the anti-sigma-factor antagonist family
ANACY_RS03075	COG0783	Belongs to the Dps family
ANACY_RS03085	COG2385	sporulation resulting in formation of a cellular spore
ANACY_RS03090	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ANACY_RS03100	COG0024	Methionine aminopeptidase
ANACY_RS03135	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ANACY_RS03155	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ANACY_RS03155	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ANACY_RS03160	COG1982	Orn Lys Arg decarboxylase major
ANACY_RS03165	COG0134	indole-3-glycerol-phosphate synthase activity
ANACY_RS03175	COG2205	protein histidine kinase activity
ANACY_RS03180	COG3292	Two component regulator propeller
ANACY_RS03180	COG2205	protein histidine kinase activity
ANACY_RS03180	COG0745	RESPONSE REGULATOR receiver
ANACY_RS03190	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ANACY_RS03195	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ANACY_RS03250	COG0514	ATP-dependent DNA helicase (RecQ)
ANACY_RS03260	COG1022	Amp-dependent synthetase and ligase
ANACY_RS03280	COG0508	dehydrogenase complex catalyzes the overall conversion of
ANACY_RS03300	COG2166	iron-sulfur cluster assembly
ANACY_RS03330	COG3609	addiction module antidote protein, CC2985 family
ANACY_RS03370	COG1429	ligase activity, forming nitrogen-metal bonds
ANACY_RS03415	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ANACY_RS03420	COG4106	trans-aconitate 2-methyltransferase activity
ANACY_RS03425	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ANACY_RS03455	COG1247	-acetyltransferase
ANACY_RS03465	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ANACY_RS03470	COG1741	Belongs to the pirin family
ANACY_RS03480	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ANACY_RS03485	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ANACY_RS03490	COG0793	Belongs to the peptidase S41A family
ANACY_RS03525	COG0826	peptidase U32
ANACY_RS03545	COG1834	amidinotransferase
ANACY_RS03740	COG0693	protein deglycase activity
ANACY_RS03760	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
ANACY_RS03765	COG0830	nickel cation binding
ANACY_RS03770	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ANACY_RS03785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ANACY_RS03795	COG3258	Cytochrome c
ANACY_RS03800	COG0723	plastoquinol--plastocyanin reductase activity
ANACY_RS03825	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ANACY_RS03830	COG0509	glycine decarboxylation via glycine cleavage system
ANACY_RS03855	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ANACY_RS03870	COG1333	cytochrome c biogenesis protein
ANACY_RS03875	COG4232	protein-disulfide reductase activity
ANACY_RS03880	COG0697	spore germination
ANACY_RS03895	COG0659	secondary active sulfate transmembrane transporter activity
ANACY_RS03905	COG0674	pyruvate-flavodoxin oxidoreductase activity
ANACY_RS03905	COG1013	pyruvate-flavodoxin oxidoreductase activity
ANACY_RS03905	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ANACY_RS03905	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ANACY_RS03955	COG0023	Translation Initiation Factor
ANACY_RS03970	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ANACY_RS04000	COG2205	protein histidine kinase activity
ANACY_RS04000	COG0784	Response regulator, receiver
ANACY_RS04000	COG5002	protein histidine kinase activity
ANACY_RS04010	COG0571	ribonuclease III activity
ANACY_RS04035	COG0598	Magnesium transport protein CorA
ANACY_RS04040	COG0681	Belongs to the peptidase S26 family
ANACY_RS04045	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ANACY_RS04050	COG0802	atpase or kinase
ANACY_RS04055	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ANACY_RS04060	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ANACY_RS04080	COG0045	succinate-CoA ligase (ADP-forming) activity
ANACY_RS04100	COG4636	protein conserved in cyanobacteria
ANACY_RS04135	COG2197	response regulator
ANACY_RS04160	COG3265	gluconokinase activity
ANACY_RS04165	COG1489	DNA binding
ANACY_RS04190	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ANACY_RS04195	COG0406	alpha-ribazole phosphatase activity
ANACY_RS04200	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
ANACY_RS04210	COG1073	alpha beta
ANACY_RS04220	COG1215	transferase activity, transferring glycosyl groups
ANACY_RS04225	COG1215	transferase activity, transferring glycosyl groups
ANACY_RS04235	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ANACY_RS04285	COG0463	Glycosyl transferase, family 2
ANACY_RS04295	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ANACY_RS04300	COG0552	protein localization to endoplasmic reticulum
ANACY_RS04305	COG2208	phosphoserine phosphatase activity
ANACY_RS04340	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ANACY_RS04350	COG2363	Small membrane protein
ANACY_RS04375	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
ANACY_RS04380	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ANACY_RS04385	COG0772	Belongs to the SEDS family
ANACY_RS04400	COG0649	NAD binding
ANACY_RS04425	COG0275	rRNA processing
ANACY_RS04440	COG4172	Belongs to the ABC transporter superfamily
ANACY_RS04470	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ANACY_RS04470	COG2022	thiamine diphosphate biosynthetic process
ANACY_RS04495	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ANACY_RS04500	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ANACY_RS04505	COG1937	Protein conserved in bacteria
ANACY_RS04510	COG0596	Alpha beta hydrolase
ANACY_RS04520	COG0702	epimerase
ANACY_RS04555	COG0514	ATP-dependent DNA helicase (RecQ)
ANACY_RS04610	COG0850	regulation of cytokinetic process
ANACY_RS04615	COG2894	cell division
ANACY_RS04620	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
ANACY_RS04650	COG0667	Aldo Keto reductase
ANACY_RS04680	COG0270	DNA (cytosine-5-)-methyltransferase activity
ANACY_RS04715	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ANACY_RS04735	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ANACY_RS04795	COG1122	ATPase activity
ANACY_RS04800	COG0357	Ribosomal RNA small subunit methyltransferase G
ANACY_RS04845	COG0538	isocitrate dehydrogenase activity
ANACY_RS04850	COG0515	serine threonine protein kinase
ANACY_RS04855	COG5002	protein histidine kinase activity
ANACY_RS04855	COG0784	Response regulator, receiver
ANACY_RS04860	COG3842	ATPase activity
ANACY_RS04875	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ANACY_RS04885	COG0697	spore germination
ANACY_RS04895	COG1943	Transposase
ANACY_RS04900	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ANACY_RS04915	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ANACY_RS04940	COG0805	protein transport
ANACY_RS04945	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
ANACY_RS04950	COG1420	regulation of RNA biosynthetic process
ANACY_RS04970	COG1045	serine acetyltransferase
ANACY_RS05020	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ANACY_RS05035	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ANACY_RS05040	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ANACY_RS05045	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ANACY_RS05050	COG3429	Glucose-6-phosphate dehydrogenase subunit
ANACY_RS05050	COG3409	Peptidoglycan-binding domain 1 protein
ANACY_RS05055	COG1797	cobyrinic acid a,c-diamide synthase activity
ANACY_RS05075	COG1615	UPF0182 protein
ANACY_RS05120	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
ANACY_RS05125	COG0716	FMN binding
ANACY_RS05160	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ANACY_RS05175	COG0440	acetolactate synthase activity
ANACY_RS05190	COG0784	Response regulator, receiver
ANACY_RS05200	COG2203	Gaf domain
ANACY_RS05200	COG0840	transmembrane signaling receptor activity
ANACY_RS05205	COG0643	Histidine kinase
ANACY_RS05205	COG2198	Histidine kinase
ANACY_RS05205	COG0784	Response regulator, receiver
ANACY_RS05225	COG3959	Transketolase, thiamine diphosphate binding domain
ANACY_RS05245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ANACY_RS05250	COG1695	Transcriptional regulator
ANACY_RS05255	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
ANACY_RS05260	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
ANACY_RS05295	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ANACY_RS05305	COG0018	arginyl-trna synthetase
ANACY_RS05350	COG0745	RESPONSE REGULATOR receiver
ANACY_RS05355	COG0642	Histidine kinase
ANACY_RS05370	COG0723	plastoquinol--plastocyanin reductase activity
ANACY_RS05420	COG2133	pyrroloquinoline quinone binding
ANACY_RS05430	COG4191	Histidine kinase
ANACY_RS05445	COG1940	carbohydrate kinase activity
ANACY_RS05465	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ANACY_RS05505	COG5002	protein histidine kinase activity
ANACY_RS05510	COG0151	Belongs to the GarS family
ANACY_RS05515	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ANACY_RS05550	COG0415	Belongs to the DNA photolyase family
ANACY_RS05555	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
ANACY_RS05570	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ANACY_RS05575	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ANACY_RS05580	COG2161	toxin-antitoxin pair type II binding
ANACY_RS05605	COG4948	Mandelate Racemase Muconate Lactonizing
ANACY_RS05665	COG1024	Enoyl-CoA hydratase
ANACY_RS05670	COG1028	Short-chain dehydrogenase reductase Sdr
ANACY_RS05680	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ANACY_RS05680	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ANACY_RS05685	COG2197	response regulator
ANACY_RS05690	COG0515	serine threonine protein kinase
ANACY_RS05690	COG2815	serine threonine protein kinase
ANACY_RS05745	COG5433	transposase activity
ANACY_RS05750	COG0697	spore germination
ANACY_RS05800	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ANACY_RS05805	COG3012	SEC-C Motif Domain Protein
ANACY_RS05810	COG2361	Protein of unknown function DUF86
ANACY_RS05875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ANACY_RS05905	COG2255	four-way junction helicase activity
ANACY_RS05930	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ANACY_RS05940	COG4644	lycopene metabolic process
ANACY_RS05960	COG1111	helicase
ANACY_RS05960	COG1205	dead DEAH box helicase
ANACY_RS05995	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ANACY_RS06000	COG0592	DNA-directed DNA polymerase activity
ANACY_RS06090	COG1487	ribonuclease activity
ANACY_RS06095	COG4974	Belongs to the 'phage' integrase family
ANACY_RS06105	COG5433	transposase activity
ANACY_RS06120	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ANACY_RS06125	COG1959	2 iron, 2 sulfur cluster binding
ANACY_RS06130	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ANACY_RS06150	COG0730	response to heat
ANACY_RS06155	COG0671	phosphoesterase, PA-phosphatase related
ANACY_RS06180	COG0730	response to heat
ANACY_RS06210	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ANACY_RS06215	COG1028	Short-chain dehydrogenase reductase Sdr
ANACY_RS06230	COG0667	Aldo Keto reductase
ANACY_RS06235	COG3659	wide pore channel activity
ANACY_RS06245	COG1116	anion transmembrane transporter activity
ANACY_RS06255	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ANACY_RS06260	COG2175	clavaminate synthase activity
ANACY_RS06265	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ANACY_RS06270	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ANACY_RS06275	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ANACY_RS06280	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ANACY_RS06285	COG0431	NADPH-dependent FMN reductase
ANACY_RS06300	COG1285	pathogenesis
ANACY_RS06305	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ANACY_RS06315	COG4221	oxidoreductase activity
ANACY_RS06320	COG0489	protein tyrosine kinase activity
ANACY_RS06330	COG2319	Wd-40 repeat
ANACY_RS06330	COG3903	Transcriptional regulator
ANACY_RS06355	COG3240	lipase activity
ANACY_RS06360	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ANACY_RS06380	COG1136	(ABC) transporter
ANACY_RS06380	COG0577	efflux transmembrane transporter activity
ANACY_RS06405	COG2091	lysine biosynthetic process via aminoadipic acid
ANACY_RS06440	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ANACY_RS06445	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ANACY_RS06475	COG0625	glutathione transferase activity
ANACY_RS06520	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ANACY_RS06525	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ANACY_RS06540	COG0667	Aldo Keto reductase
ANACY_RS06545	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ANACY_RS06550	COG1132	(ABC) transporter
ANACY_RS06670	COG0673	inositol 2-dehydrogenase activity
ANACY_RS06695	COG2304	oxidoreductase activity
ANACY_RS06705	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ANACY_RS06720	COG1902	pentaerythritol trinitrate reductase activity
ANACY_RS06735	COG0180	Tryptophanyl-tRNA synthetase
ANACY_RS06740	COG1032	radical SAM domain protein
ANACY_RS06765	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ANACY_RS06780	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ANACY_RS06805	COG1872	DUF167
ANACY_RS06815	COG0582	viral genome integration into host DNA
ANACY_RS06915	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ANACY_RS06920	COG0640	Transcriptional regulator
ANACY_RS06925	COG1121	(ABC) transporter
ANACY_RS06930	COG0803	Belongs to the bacterial solute-binding protein 9 family
ANACY_RS06935	COG3659	wide pore channel activity
ANACY_RS06940	COG0009	L-threonylcarbamoyladenylate synthase
ANACY_RS06945	COG3437	response regulator, receiver
ANACY_RS06945	COG4999	Histidine kinase
ANACY_RS06945	COG3850	Histidine kinase
ANACY_RS06945	COG2205	protein histidine kinase activity
ANACY_RS06950	COG0456	acetyltransferase
ANACY_RS06965	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ANACY_RS06970	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ANACY_RS06975	COG0508	dehydrogenase complex catalyzes the overall conversion of
ANACY_RS06975	COG0022	dehydrogenase e1 component
ANACY_RS07015	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ANACY_RS07050	COG1187	pseudouridine synthase activity
ANACY_RS07060	COG3266	domain, Protein
ANACY_RS07060	COG0515	serine threonine protein kinase
ANACY_RS07085	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ANACY_RS07100	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ANACY_RS07115	COG0673	inositol 2-dehydrogenase activity
ANACY_RS07120	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ANACY_RS07130	COG4968	Prepilin-type N-terminal cleavage methylation domain
ANACY_RS07135	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ANACY_RS07140	COG0492	ferredoxin-NADP+ reductase activity
ANACY_RS07145	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ANACY_RS07150	COG1940	carbohydrate kinase activity
ANACY_RS07160	COG0504	CTP synthase activity
ANACY_RS07165	COG3103	Sh3 type 3 domain protein
ANACY_RS07165	COG0860	N-Acetylmuramoyl-L-alanine amidase
ANACY_RS07165	COG4991	sh3 domain protein
ANACY_RS07170	COG3103	Sh3 type 3 domain protein
ANACY_RS07170	COG0860	N-Acetylmuramoyl-L-alanine amidase
ANACY_RS07170	COG4991	sh3 domain protein
ANACY_RS07190	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ANACY_RS07205	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
ANACY_RS07215	COG3977	Valine--pyruvate aminotransferase
ANACY_RS07220	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ANACY_RS07245	COG0837	glucose binding
ANACY_RS07270	COG0157	Belongs to the NadC ModD family
ANACY_RS07300	COG0745	RESPONSE REGULATOR receiver
ANACY_RS07355	COG0243	molybdopterin cofactor binding
ANACY_RS07360	COG2223	nitrite transmembrane transporter activity
ANACY_RS07400	COG0583	DNA-binding transcription factor activity
ANACY_RS07405	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ANACY_RS07425	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
ANACY_RS07430	COG1518	maintenance of DNA repeat elements
ANACY_RS07465	COG4804	nuclease activity
ANACY_RS07470	COG2442	InterPro IPR007367
ANACY_RS07495	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ANACY_RS07500	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ANACY_RS07505	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
ANACY_RS07525	COG1027	Aspartate ammonia-lyase
ANACY_RS07530	COG0750	zinc metalloprotease
ANACY_RS07535	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ANACY_RS07540	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ANACY_RS07550	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ANACY_RS07565	COG0242	peptide deformylase activity
ANACY_RS07585	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ANACY_RS07585	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ANACY_RS07600	COG0793	Belongs to the peptidase S41A family
ANACY_RS07615	COG2501	S4 domain
ANACY_RS07620	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ANACY_RS07640	COG1842	Phage shock protein A
ANACY_RS07645	COG1842	Phage shock protein A
ANACY_RS07650	COG3118	belongs to the thioredoxin family
ANACY_RS07655	COG0436	Aminotransferase
ANACY_RS07665	COG0322	excinuclease ABC activity
ANACY_RS07685	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ANACY_RS07700	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ANACY_RS07705	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ANACY_RS07735	COG2770	Histidine kinase
ANACY_RS07735	COG2208	phosphoserine phosphatase activity
ANACY_RS07740	COG1366	Belongs to the anti-sigma-factor antagonist family
ANACY_RS07745	COG0515	serine threonine protein kinase
ANACY_RS07760	COG0628	permease
ANACY_RS07765	COG0215	cysteine-tRNA ligase activity
ANACY_RS07770	COG0523	cobalamin synthesis protein
ANACY_RS07775	COG1785	Belongs to the alkaline phosphatase family
ANACY_RS07785	COG0521	Mo-molybdopterin cofactor biosynthetic process
ANACY_RS07795	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
ANACY_RS07800	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ANACY_RS07820	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ANACY_RS07840	COG0395	ABC-type sugar transport system, permease component
ANACY_RS07845	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ANACY_RS07870	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
ANACY_RS07910	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ANACY_RS07915	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ANACY_RS07920	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
ANACY_RS07935	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ANACY_RS07950	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ANACY_RS07965	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ANACY_RS08000	COG5002	protein histidine kinase activity
ANACY_RS08000	COG0784	Response regulator, receiver
ANACY_RS08030	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ANACY_RS08045	COG0745	RESPONSE REGULATOR receiver
ANACY_RS08050	COG5002	protein histidine kinase activity
ANACY_RS08055	COG0704	Plays a role in the regulation of phosphate uptake
ANACY_RS08060	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ANACY_RS08065	COG3659	wide pore channel activity
ANACY_RS08070	COG3659	wide pore channel activity
ANACY_RS08080	COG1361	Conserved repeat domain
ANACY_RS08085	COG2205	protein histidine kinase activity
ANACY_RS08105	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ANACY_RS08130	COG3852	Histidine kinase
ANACY_RS08140	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ANACY_RS08140	COG0426	domain, Protein
ANACY_RS08145	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ANACY_RS08145	COG0426	domain, Protein
ANACY_RS08170	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ANACY_RS08180	COG0745	RESPONSE REGULATOR receiver
ANACY_RS08190	COG5002	protein histidine kinase activity
ANACY_RS08195	COG5002	protein histidine kinase activity
ANACY_RS08205	COG0628	permease
ANACY_RS08215	COG1316	TRANSCRIPTIONal
ANACY_RS08245	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ANACY_RS08245	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ANACY_RS08260	COG0393	Putative heavy-metal-binding
ANACY_RS08280	COG0719	Fe-S assembly protein
ANACY_RS08285	COG0396	ATPase activity
ANACY_RS08290	COG0719	Fe-S assembly protein
ANACY_RS08295	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ANACY_RS08305	COG0523	cobalamin synthesis protein
ANACY_RS08325	COG2124	cytochrome p450
ANACY_RS08355	COG2124	cytochrome p450
ANACY_RS08360	COG0297	glycogen (starch) synthase activity
ANACY_RS08415	COG3185	4-Hydroxyphenylpyruvate dioxygenase
ANACY_RS08420	COG4221	oxidoreductase activity
ANACY_RS08460	COG1619	proteins homologs of microcin C7 resistance protein MccF
ANACY_RS08485	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ANACY_RS08535	COG0237	dephospho-CoA kinase activity
ANACY_RS08535	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ANACY_RS08560	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ANACY_RS08570	COG0356	it plays a direct role in the translocation of protons across the membrane
ANACY_RS08575	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ANACY_RS08580	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ANACY_RS08585	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ANACY_RS08590	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ANACY_RS08595	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ANACY_RS08600	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ANACY_RS08640	COG0431	NADPH-dependent FMN reductase
ANACY_RS08645	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ANACY_RS08670	COG3706	GGDEF domain
ANACY_RS08670	COG2203	Gaf domain
ANACY_RS08670	COG4251	negative regulation of phosphorylation
ANACY_RS08670	COG5001	Diguanylate cyclase
ANACY_RS08680	COG0582	viral genome integration into host DNA
ANACY_RS08690	COG2442	InterPro IPR007367
ANACY_RS08735	COG4680	protein conserved in bacteria
ANACY_RS08745	COG2337	Toxic component of a toxin-antitoxin (TA) module
ANACY_RS08860	COG0298	carbon dioxide binding
ANACY_RS08865	COG0409	Hydrogenase expression formation protein
ANACY_RS08880	COG0375	protein maturation
ANACY_RS08885	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ANACY_RS08895	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ANACY_RS08900	COG0284	orotidine-5'-phosphate decarboxylase activity
ANACY_RS08900	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ANACY_RS08905	COG1496	oxidoreductase activity
ANACY_RS08910	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ANACY_RS08910	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ANACY_RS08915	COG0741	lytic transglycosylase activity
ANACY_RS08915	COG0739	heme binding
ANACY_RS08915	COG1196	nuclear chromosome segregation
ANACY_RS08935	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ANACY_RS08945	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ANACY_RS08950	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ANACY_RS09020	COG3237	CsbD-like
ANACY_RS09035	COG0762	integral membrane protein
ANACY_RS09045	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ANACY_RS09060	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ANACY_RS09080	COG1131	(ABC) transporter
ANACY_RS09090	COG0473	3-isopropylmalate dehydrogenase activity
ANACY_RS09100	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ANACY_RS09105	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ANACY_RS09150	COG0395	ABC-type sugar transport system, permease component
ANACY_RS09155	COG2010	Cytochrome c
ANACY_RS09160	COG3794	PFAM blue (type 1) copper domain protein
ANACY_RS09165	COG2010	Cytochrome c
ANACY_RS09190	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ANACY_RS09195	COG2205	protein histidine kinase activity
ANACY_RS09195	COG2202	Pas domain
ANACY_RS09210	COG0784	Response regulator, receiver
ANACY_RS09215	COG4999	Histidine kinase
ANACY_RS09215	COG3850	Histidine kinase
ANACY_RS09215	COG2205	protein histidine kinase activity
ANACY_RS09215	COG3437	response regulator, receiver
ANACY_RS09225	COG2197	response regulator
ANACY_RS09275	COG0438	transferase activity, transferring glycosyl groups
ANACY_RS09290	COG1357	PFAM Pentapeptide repeats (8 copies)
ANACY_RS09290	COG0515	serine threonine protein kinase
ANACY_RS09315	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ANACY_RS09320	COG0784	Response regulator, receiver
ANACY_RS09325	COG0564	pseudouridine synthase activity
ANACY_RS09340	COG0237	dephospho-CoA kinase activity
ANACY_RS09345	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ANACY_RS09350	COG1413	lyase activity
ANACY_RS09355	COG1413	lyase activity
ANACY_RS09360	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ANACY_RS09365	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ANACY_RS09370	COG0237	dephospho-CoA kinase activity
ANACY_RS09385	COG0019	diaminopimelate decarboxylase activity
ANACY_RS09400	COG0367	asparagine synthase
ANACY_RS09415	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ANACY_RS09415	COG0189	ligase activity
ANACY_RS09435	COG1054	Belongs to the UPF0176 family
ANACY_RS09445	COG0572	uridine kinase
ANACY_RS09450	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
ANACY_RS09455	COG4251	negative regulation of phosphorylation
ANACY_RS09455	COG5001	Diguanylate cyclase
ANACY_RS09455	COG3706	GGDEF domain
ANACY_RS09455	COG2203	Gaf domain
ANACY_RS09455	COG5001	Diguanylate cyclase
ANACY_RS09455	COG4251	negative regulation of phosphorylation
ANACY_RS09455	COG3706	GGDEF domain
ANACY_RS09455	COG2203	Gaf domain
ANACY_RS09470	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ANACY_RS09480	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ANACY_RS09495	COG1085	galactose-1-phosphate uridylyltransferase
ANACY_RS09510	COG3507	Belongs to the glycosyl hydrolase 43 family
ANACY_RS09515	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ANACY_RS09525	COG0562	UDP-galactopyranose mutase
ANACY_RS09540	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ANACY_RS09560	COG1012	belongs to the aldehyde dehydrogenase family
ANACY_RS09595	COG2205	protein histidine kinase activity
ANACY_RS09595	COG0784	Response regulator, receiver
ANACY_RS09595	COG2198	Histidine kinase
ANACY_RS09605	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ANACY_RS09630	COG0123	including yeast histone deacetylase and acetoin utilization protein
ANACY_RS09660	COG2274	protein secretion by the type I secretion system
ANACY_RS09665	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ANACY_RS09670	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ANACY_RS09690	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ANACY_RS09695	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ANACY_RS09700	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ANACY_RS09710	COG0515	serine threonine protein kinase
ANACY_RS09715	COG0515	serine threonine protein kinase
ANACY_RS09735	COG1773	rubredoxin
ANACY_RS09740	COG4447	cellulose binding
ANACY_RS09790	COG1979	alcohol dehydrogenase
ANACY_RS09830	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
ANACY_RS09840	COG0739	heme binding
ANACY_RS09855	COG5001	Diguanylate cyclase
ANACY_RS09855	COG4251	negative regulation of phosphorylation
ANACY_RS09855	COG3706	GGDEF domain
ANACY_RS09855	COG2203	Gaf domain
ANACY_RS09860	COG4221	oxidoreductase activity
ANACY_RS09865	COG1309	transcriptional regulator
ANACY_RS09885	COG1252	NADH dehydrogenase
ANACY_RS09895	COG1733	regulation of RNA biosynthetic process
ANACY_RS09900	COG0702	epimerase
ANACY_RS09915	COG1104	cysteine desulfurase activity
ANACY_RS09940	COG0793	Belongs to the peptidase S41A family
ANACY_RS09945	COG2203	Gaf domain
ANACY_RS09945	COG3706	GGDEF domain
ANACY_RS09945	COG4251	negative regulation of phosphorylation
ANACY_RS09945	COG5001	Diguanylate cyclase
ANACY_RS09960	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ANACY_RS09995	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ANACY_RS10025	COG1196	nuclear chromosome segregation
ANACY_RS10025	COG0739	heme binding
ANACY_RS10025	COG0741	lytic transglycosylase activity
ANACY_RS10030	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ANACY_RS10045	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ANACY_RS10065	COG2197	response regulator
ANACY_RS10080	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ANACY_RS10090	COG0776	regulation of translation
ANACY_RS10130	COG0285	dihydrofolate synthase activity
ANACY_RS10140	COG0110	maltose O-acetyltransferase activity
ANACY_RS10155	COG0612	Peptidase, M16
ANACY_RS10165	COG0024	Methionine aminopeptidase
ANACY_RS10170	COG0154	amidase activity
ANACY_RS10190	COG4106	trans-aconitate 2-methyltransferase activity
ANACY_RS10200	COG1649	PFAM Uncharacterised BCR, COG1649
ANACY_RS10220	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ANACY_RS10225	COG1252	NADH dehydrogenase
ANACY_RS10245	COG0277	FAD linked oxidase domain protein
ANACY_RS10250	COG0247	lactate metabolic process
ANACY_RS10255	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ANACY_RS10270	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ANACY_RS10330	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ANACY_RS10340	COG0822	iron-sulfur transferase activity
ANACY_RS10340	COG2906	2 iron, 2 sulfur cluster binding
ANACY_RS10340	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ANACY_RS10345	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
ANACY_RS10380	COG0582	viral genome integration into host DNA
ANACY_RS10385	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
ANACY_RS10395	COG0582	viral genome integration into host DNA
ANACY_RS10420	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ANACY_RS10470	COG0582	viral genome integration into host DNA
ANACY_RS10485	COG5433	transposase activity
ANACY_RS10525	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ANACY_RS10545	COG4974	Belongs to the 'phage' integrase family
ANACY_RS10550	COG1132	(ABC) transporter
ANACY_RS10610	COG1192	Involved in chromosome partitioning
ANACY_RS10660	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
ANACY_RS10970	COG0582	viral genome integration into host DNA
ANACY_RS10975	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
ANACY_RS10985	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
ANACY_RS10990	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
ANACY_RS11005	COG5420	small protein containing a coiled-coil domain
ANACY_RS11015	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ANACY_RS11020	COG0316	Belongs to the HesB IscA family
ANACY_RS11025	COG0633	Ferredoxin
ANACY_RS11055	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ANACY_RS11055	COG2755	lipolytic protein G-D-S-L family
ANACY_RS11100	COG1252	NADH dehydrogenase
ANACY_RS11105	COG1181	Belongs to the D-alanine--D-alanine ligase family
ANACY_RS11125	COG1295	ribonuclease BN
ANACY_RS11155	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ANACY_RS11175	COG1902	pentaerythritol trinitrate reductase activity
ANACY_RS11185	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ANACY_RS11195	COG0004	ammonium transporteR
ANACY_RS11200	COG0515	serine threonine protein kinase
ANACY_RS11200	COG1357	PFAM Pentapeptide repeats (8 copies)
ANACY_RS11230	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ANACY_RS11235	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
ANACY_RS11260	COG0751	glycine-tRNA ligase activity
ANACY_RS11265	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ANACY_RS11280	COG2234	aminopeptidase activity
ANACY_RS11300	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ANACY_RS11315	COG1132	(ABC) transporter
ANACY_RS11320	COG0741	lytic transglycosylase activity
ANACY_RS11335	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ANACY_RS11345	COG0217	transcriptional regulatory protein
ANACY_RS11350	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ANACY_RS11355	COG0228	four-way junction DNA binding
ANACY_RS11365	COG1702	phosphate starvation-inducible protein PhoH
ANACY_RS11385	COG1132	(ABC) transporter
ANACY_RS11405	COG0563	adenylate kinase activity
ANACY_RS11415	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ANACY_RS11420	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ANACY_RS11425	COG0363	glucosamine-6-phosphate deaminase activity
ANACY_RS11430	COG1716	ATPase activity
ANACY_RS11450	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ANACY_RS11455	COG2770	Histidine kinase
ANACY_RS11455	COG2208	phosphoserine phosphatase activity
ANACY_RS11475	COG1366	Belongs to the anti-sigma-factor antagonist family
ANACY_RS11510	COG3659	wide pore channel activity
ANACY_RS11525	COG1234	tRNA 3'-trailer cleavage
ANACY_RS11555	COG2373	Large extracellular alpha-helical protein
ANACY_RS11560	COG4953	penicillin-binding protein 1C
ANACY_RS11565	COG1090	epimerase
ANACY_RS11580	COG0316	Belongs to the HesB IscA family
ANACY_RS11595	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
ANACY_RS11605	COG0753	catalase activity
ANACY_RS11615	COG1492	cobalamin metabolic process
ANACY_RS11625	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ANACY_RS11655	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
ANACY_RS11660	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
ANACY_RS11670	COG0457	Tetratricopeptide repeat
ANACY_RS11670	COG0463	Glycosyl transferase, family 2
ANACY_RS11680	COG0436	Aminotransferase
ANACY_RS11690	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ANACY_RS11720	COG0596	Alpha beta hydrolase
ANACY_RS11730	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ANACY_RS11735	COG0572	uridine kinase
ANACY_RS11740	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ANACY_RS11745	COG0460	homoserine dehydrogenase
ANACY_RS11750	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ANACY_RS11755	COG0784	Response regulator, receiver
ANACY_RS11755	COG2205	protein histidine kinase activity
ANACY_RS11785	COG2815	serine threonine protein kinase
ANACY_RS11785	COG0515	serine threonine protein kinase
ANACY_RS11805	COG1131	(ABC) transporter
ANACY_RS11810	COG2203	Gaf domain
ANACY_RS11810	COG3706	GGDEF domain
ANACY_RS11810	COG4251	negative regulation of phosphorylation
ANACY_RS11810	COG5001	Diguanylate cyclase
ANACY_RS11815	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ANACY_RS11825	COG1316	TRANSCRIPTIONal
ANACY_RS11830	COG1357	PFAM Pentapeptide repeats (8 copies)
ANACY_RS11840	COG0728	peptidoglycan biosynthetic process
ANACY_RS11855	COG4636	protein conserved in cyanobacteria
ANACY_RS11875	COG1950	PFAM Membrane protein of
ANACY_RS11885	COG2183	response to ionizing radiation
ANACY_RS11920	COG3266	domain, Protein
ANACY_RS11920	COG4932	domain protein
ANACY_RS11920	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
ANACY_RS11920	COG3266	domain, Protein
ANACY_RS11920	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
ANACY_RS11920	COG4932	domain protein
ANACY_RS11930	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ANACY_RS11965	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ANACY_RS11970	COG0193	aminoacyl-tRNA hydrolase activity
ANACY_RS11975	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ANACY_RS11980	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ANACY_RS11995	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ANACY_RS12005	COG1218	3'(2'),5'-bisphosphate nucleotidase
ANACY_RS12090	COG0166	Belongs to the GPI family
ANACY_RS12125	COG1598	PFAM Uncharacterised protein family UPF0150
ANACY_RS12130	COG0730	response to heat
ANACY_RS12135	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ANACY_RS12150	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ANACY_RS12155	COG1494	fructose-1,6-bisphosphatase
ANACY_RS12160	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ANACY_RS12165	COG0590	tRNA wobble adenosine to inosine editing
ANACY_RS12175	COG4249	Peptidase C14 caspase catalytic subunit p20
ANACY_RS12175	COG2319	Wd-40 repeat
ANACY_RS12190	COG4935	Belongs to the peptidase S8 family
ANACY_RS12190	COG1404	Belongs to the peptidase S8 family
ANACY_RS12200	COG0271	Belongs to the BolA IbaG family
ANACY_RS12205	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ANACY_RS12210	COG2814	Major facilitator Superfamily
ANACY_RS12215	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ANACY_RS12225	COG0745	RESPONSE REGULATOR receiver
ANACY_RS12230	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ANACY_RS12270	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ANACY_RS12290	COG1530	ribonuclease E activity
ANACY_RS12295	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ANACY_RS12305	COG1605	Chorismate mutase
ANACY_RS12305	COG0077	Prephenate dehydratase
ANACY_RS12310	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ANACY_RS12315	COG0051	transcription antitermination factor activity, RNA binding
ANACY_RS12320	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ANACY_RS12325	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ANACY_RS12330	COG0049	tRNA binding
ANACY_RS12335	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ANACY_RS12340	COG0316	Belongs to the HesB IscA family
ANACY_RS12345	COG0662	Cupin 2, conserved barrel domain protein
ANACY_RS12345	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
ANACY_RS12355	COG0067	glutamate synthase
ANACY_RS12355	COG0069	glutamate synthase activity
ANACY_RS12355	COG0070	glutamate synthase
ANACY_RS12370	COG0463	Glycosyl transferase, family 2
ANACY_RS12390	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ANACY_RS12410	COG0824	Thioesterase
ANACY_RS12435	COG0501	Belongs to the peptidase M48B family
ANACY_RS12515	COG5002	protein histidine kinase activity
ANACY_RS12520	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ANACY_RS12525	COG2201	protein-glutamate methylesterase activity
ANACY_RS12545	COG2205	protein histidine kinase activity
ANACY_RS12560	COG3240	lipase activity
ANACY_RS12605	COG0668	transmembrane transport
ANACY_RS12625	COG1160	GTP binding
ANACY_RS12630	COG5001	Diguanylate cyclase
ANACY_RS12630	COG1716	ATPase activity
ANACY_RS12645	COG0149	triose-phosphate isomerase activity
ANACY_RS12650	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ANACY_RS12655	COG0330	HflC and HflK could
ANACY_RS12660	COG4279	zinc finger
ANACY_RS12670	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ANACY_RS12670	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ANACY_RS12700	COG1185	polyribonucleotide nucleotidyltransferase activity
ANACY_RS12740	COG4372	Transposase
ANACY_RS12745	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ANACY_RS12750	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ANACY_RS12755	COG0131	Imidazoleglycerol-phosphate dehydratase
ANACY_RS12760	COG1131	(ABC) transporter
ANACY_RS12765	COG1596	polysaccharide export
ANACY_RS12785	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ANACY_RS12790	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ANACY_RS12810	COG1063	alcohol dehydrogenase
ANACY_RS12830	COG3266	domain, Protein
ANACY_RS12830	COG0515	serine threonine protein kinase
ANACY_RS12850	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ANACY_RS12855	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ANACY_RS12860	COG0085	RNA polymerase activity
ANACY_RS12865	COG0084	hydrolase, TatD family'
ANACY_RS12870	COG0268	Binds directly to 16S ribosomal RNA
ANACY_RS12875	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ANACY_RS12880	COG0589	response to stress
ANACY_RS12890	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ANACY_RS12935	COG0612	Peptidase, M16
ANACY_RS12940	COG3001	Fructosamine kinase
ANACY_RS12950	COG0515	serine threonine protein kinase
ANACY_RS12950	COG3266	domain, Protein
ANACY_RS12955	COG0222	ribosome binding
ANACY_RS12960	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ANACY_RS12965	COG0081	regulation of translation
ANACY_RS12970	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ANACY_RS12975	COG0250	Participates in transcription elongation, termination and antitermination
ANACY_RS12980	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ANACY_RS12990	COG0335	large ribosomal subunit rRNA binding
ANACY_RS12995	COG0463	Glycosyl transferase, family 2
ANACY_RS13005	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ANACY_RS13025	COG0724	RNA recognition motif
ANACY_RS13040	COG3654	unkown
ANACY_RS13050	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ANACY_RS13050	COG0426	domain, Protein
ANACY_RS13055	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ANACY_RS13055	COG0426	domain, Protein
ANACY_RS13060	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ANACY_RS13090	COG0165	Argininosuccinate lyase
ANACY_RS13100	COG1691	(AIR) carboxylase
ANACY_RS13105	COG0747	negative chemotaxis
ANACY_RS13120	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ANACY_RS13125	COG0336	Belongs to the RNA methyltransferase TrmD family
ANACY_RS13130	COG4242	Belongs to the peptidase S51 family
ANACY_RS13135	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ANACY_RS13135	COG0189	ligase activity
ANACY_RS13140	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ANACY_RS13145	COG3266	domain, Protein
ANACY_RS13145	COG0515	serine threonine protein kinase
ANACY_RS13150	COG0515	serine threonine protein kinase
ANACY_RS13160	COG0575	Belongs to the CDS family
ANACY_RS13170	COG1187	pseudouridine synthase activity
ANACY_RS13180	COG1640	4-alpha-glucanotransferase
ANACY_RS13190	COG0251	oxidation-reduction process
ANACY_RS13195	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ANACY_RS13210	COG1053	succinate dehydrogenase
ANACY_RS13230	COG0277	FAD linked oxidase domain protein
ANACY_RS13235	COG1649	PFAM Uncharacterised BCR, COG1649
ANACY_RS13245	COG4251	negative regulation of phosphorylation
ANACY_RS13245	COG2203	Gaf domain
ANACY_RS13245	COG5001	Diguanylate cyclase
ANACY_RS13245	COG3706	GGDEF domain
ANACY_RS13270	COG0148	phosphopyruvate hydratase activity
ANACY_RS13275	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ANACY_RS13280	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ANACY_RS13280	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ANACY_RS13305	COG0646	methionine synthase
ANACY_RS13305	COG1410	methionine synthase
ANACY_RS13315	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ANACY_RS13335	COG0783	Belongs to the Dps family
ANACY_RS13340	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ANACY_RS13345	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ANACY_RS13365	COG0517	IMP dehydrogenase activity
ANACY_RS13365	COG0516	GMP reductase activity
ANACY_RS13385	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ANACY_RS13395	COG2046	Belongs to the sulfate adenylyltransferase family
ANACY_RS13425	COG0482	sulfurtransferase activity
ANACY_RS13435	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ANACY_RS13435	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ANACY_RS13455	COG2119	membrane
ANACY_RS13465	COG4680	protein conserved in bacteria
ANACY_RS13475	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ANACY_RS13480	COG0187	DNA topoisomerase II activity
ANACY_RS13480	COG1372	Participates in initiation and elongation during chromosome replication
ANACY_RS13485	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ANACY_RS13490	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ANACY_RS13495	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ANACY_RS13515	COG0577	efflux transmembrane transporter activity
ANACY_RS13515	COG1136	(ABC) transporter
ANACY_RS13520	COG1136	(ABC) transporter
ANACY_RS13530	COG1309	transcriptional regulator
ANACY_RS13540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ANACY_RS13545	COG1136	(ABC) transporter
ANACY_RS13545	COG0577	efflux transmembrane transporter activity
ANACY_RS13550	COG1136	(ABC) transporter
ANACY_RS13555	COG2205	protein histidine kinase activity
ANACY_RS13555	COG0784	Response regulator, receiver
ANACY_RS13560	COG2197	response regulator
ANACY_RS13580	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ANACY_RS13585	COG0546	phosphoglycolate phosphatase activity
ANACY_RS13615	COG2884	Cell division ATP-binding protein ftsE
ANACY_RS13625	COG3344	reverse transcriptase
ANACY_RS13660	COG4783	chaperone-mediated protein folding
ANACY_RS13700	COG4636	protein conserved in cyanobacteria
ANACY_RS13705	COG0542	response to heat
ANACY_RS13710	COG0346	lactoylglutathione lyase activity
ANACY_RS13735	COG1136	(ABC) transporter
ANACY_RS13735	COG0577	efflux transmembrane transporter activity
ANACY_RS13740	COG0628	permease
ANACY_RS13760	COG3706	GGDEF domain
ANACY_RS13760	COG2203	Gaf domain
ANACY_RS13760	COG4251	negative regulation of phosphorylation
ANACY_RS13760	COG5001	Diguanylate cyclase
ANACY_RS13770	COG2176	DNA-directed DNA polymerase activity
ANACY_RS13775	COG1215	transferase activity, transferring glycosyl groups
ANACY_RS13775	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ANACY_RS13785	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ANACY_RS13790	COG3118	belongs to the thioredoxin family
ANACY_RS13800	COG0583	DNA-binding transcription factor activity
ANACY_RS13805	COG0515	serine threonine protein kinase
ANACY_RS13820	COG0778	Nitroreductase
ANACY_RS13825	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ANACY_RS13830	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ANACY_RS13835	COG0018	arginyl-trna synthetase
ANACY_RS13840	COG0561	phosphatase activity
ANACY_RS13845	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ANACY_RS13845	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ANACY_RS13850	COG2203	Gaf domain
ANACY_RS13850	COG2199	diguanylate cyclase activity
ANACY_RS13865	COG0464	growth
ANACY_RS13890	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ANACY_RS13905	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ANACY_RS13950	COG1487	ribonuclease activity
ANACY_RS13995	COG0594	ribonuclease P activity
ANACY_RS14005	COG0706	membrane insertase activity
ANACY_RS14055	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ANACY_RS14065	COG5001	Diguanylate cyclase
ANACY_RS14065	COG1716	ATPase activity
ANACY_RS14070	COG0419	ATPase involved in DNA repair
ANACY_RS14090	COG0745	RESPONSE REGULATOR receiver
ANACY_RS14095	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ANACY_RS14115	COG0779	Required for maturation of 30S ribosomal subunits
ANACY_RS14120	COG0195	Participates in both transcription termination and antitermination
ANACY_RS14135	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ANACY_RS14135	COG3266	domain, Protein
ANACY_RS14145	COG1361	Conserved repeat domain
ANACY_RS14195	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ANACY_RS14260	COG1032	radical SAM domain protein
ANACY_RS14305	COG5002	protein histidine kinase activity
ANACY_RS14315	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ANACY_RS14320	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
ANACY_RS14325	COG2205	protein histidine kinase activity
ANACY_RS14325	COG2202	Pas domain
ANACY_RS14340	COG0735	belongs to the Fur family
ANACY_RS14345	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ANACY_RS14350	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ANACY_RS14355	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ANACY_RS14380	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
ANACY_RS14385	COG0436	Aminotransferase
ANACY_RS14395	COG1285	pathogenesis
ANACY_RS14405	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ANACY_RS14410	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ANACY_RS14420	COG1672	PFAM Archaeal ATPase
ANACY_RS14430	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ANACY_RS14460	COG4680	protein conserved in bacteria
ANACY_RS14495	COG1122	ATPase activity
ANACY_RS14505	COG0310	cobalt ion transport
ANACY_RS14530	COG2132	Multicopper oxidase
ANACY_RS14555	COG0672	)-iron permease
ANACY_RS14560	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ANACY_RS14565	COG0746	molybdenum cofactor guanylyltransferase activity
ANACY_RS14575	COG1331	Highly conserved protein containing a thioredoxin domain
ANACY_RS14585	COG0740	serine-type endopeptidase activity
ANACY_RS14595	COG0557	exoribonuclease II activity
ANACY_RS14600	COG0163	prenyltransferase activity
ANACY_RS14615	COG2319	Wd-40 repeat
ANACY_RS14615	COG3903	Transcriptional regulator
ANACY_RS14620	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ANACY_RS14625	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ANACY_RS14645	COG0259	pyridoxamine-phosphate oxidase activity
ANACY_RS14650	COG0628	permease
ANACY_RS14660	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ANACY_RS14665	COG1166	arginine decarboxylase activity
ANACY_RS14675	COG0105	UTP biosynthetic process
ANACY_RS14680	COG0861	Integral membrane protein TerC family
ANACY_RS14730	COG1943	Transposase
ANACY_RS14735	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ANACY_RS14780	COG2010	Cytochrome c
ANACY_RS14800	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ANACY_RS14815	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ANACY_RS14860	COG0651	ATP synthesis coupled electron transport
ANACY_RS14865	COG1006	Multisubunit Na H antiporter MnhC subunit
ANACY_RS14875	COG0765	amino acid transport
ANACY_RS14915	COG0625	glutathione transferase activity
ANACY_RS14970	COG0215	cysteine-tRNA ligase activity
ANACY_RS14990	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ANACY_RS15020	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ANACY_RS15025	COG0284	orotidine-5'-phosphate decarboxylase activity
ANACY_RS15050	COG1573	uracil-dna glycosylase
ANACY_RS15065	COG0154	amidase activity
ANACY_RS15070	COG1733	regulation of RNA biosynthetic process
ANACY_RS15085	COG0587	DNA-directed DNA polymerase activity
ANACY_RS15095	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
ANACY_RS15115	COG1136	(ABC) transporter
ANACY_RS15125	COG1566	PFAM secretion protein HlyD family protein
ANACY_RS15135	COG0604	alcohol dehydrogenase
ANACY_RS15135	COG3321	synthase
ANACY_RS15145	COG2070	2-Nitropropane dioxygenase
ANACY_RS15145	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ANACY_RS15165	COG3320	Male sterility
ANACY_RS15165	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ANACY_RS15225	COG4932	domain protein
ANACY_RS15225	COG3266	domain, Protein
ANACY_RS15225	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
ANACY_RS15245	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ANACY_RS15250	COG1799	cell septum assembly
ANACY_RS15255	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ANACY_RS15295	COG4581	dead DEAH box helicase
ANACY_RS15325	COG2217	Heavy metal translocating P-type atpase
ANACY_RS15355	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ANACY_RS15365	COG0405	Gamma-glutamyltransferase
ANACY_RS15370	COG1662	PFAM IS1 transposase
ANACY_RS15375	COG0405	Gamma-glutamyltransferase
ANACY_RS15390	COG3852	Histidine kinase
ANACY_RS15395	COG0625	glutathione transferase activity
ANACY_RS15400	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ANACY_RS15405	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ANACY_RS15420	COG0731	radical SAM domain protein
ANACY_RS15430	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ANACY_RS15435	COG0588	phosphoglycerate mutase activity
ANACY_RS15495	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ANACY_RS15510	COG3266	domain, Protein
ANACY_RS15510	COG0515	serine threonine protein kinase
ANACY_RS15515	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ANACY_RS15520	COG4221	oxidoreductase activity
ANACY_RS15530	COG0598	Magnesium transport protein CorA
ANACY_RS15565	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ANACY_RS15570	COG0581	inorganic phosphate transmembrane transporter activity
ANACY_RS15575	COG0573	inorganic phosphate transmembrane transporter activity
ANACY_RS15580	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ANACY_RS15595	COG0300	oxidoreductase activity
ANACY_RS15600	COG3320	Male sterility
ANACY_RS15600	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ANACY_RS15605	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ANACY_RS15605	COG2070	2-Nitropropane dioxygenase
ANACY_RS15625	COG1028	Short-chain dehydrogenase reductase Sdr
ANACY_RS15625	COG3321	synthase
ANACY_RS15625	COG4221	oxidoreductase activity
ANACY_RS15625	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ANACY_RS15630	COG0604	alcohol dehydrogenase
ANACY_RS15630	COG3321	synthase
ANACY_RS15670	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ANACY_RS15675	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
ANACY_RS15680	COG3639	organic phosphonate transmembrane transporter activity
ANACY_RS15685	COG3624	Phosphonate C-P lyase system protein PhnG
ANACY_RS15700	COG3626	phosphonate metabolism
ANACY_RS15705	COG3454	Phosphonate metabolism
ANACY_RS15710	COG3627	carbon phosphorus lyase activity
ANACY_RS15715	COG4107	phosphonate C-P lyase system protein PhnK
ANACY_RS15720	COG4778	phosphonate C-P lyase system protein PhnL
ANACY_RS15730	COG2201	protein-glutamate methylesterase activity
ANACY_RS15745	COG0840	transmembrane signaling receptor activity
ANACY_RS15745	COG2203	Gaf domain
ANACY_RS15750	COG0643	Histidine kinase
ANACY_RS15750	COG2198	Histidine kinase
ANACY_RS15750	COG0784	Response regulator, receiver
ANACY_RS15760	COG1176	ABC-type spermidine putrescine transport system, permease component I
ANACY_RS15770	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ANACY_RS15775	COG3842	ATPase activity
ANACY_RS15780	COG0768	penicillin binding
ANACY_RS15795	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
ANACY_RS15800	COG2211	Major facilitator Superfamily
ANACY_RS15830	COG0584	glycerophosphoryl diester phosphodiesterase
ANACY_RS15835	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ANACY_RS15870	COG0438	transferase activity, transferring glycosyl groups
ANACY_RS15875	COG0463	Glycosyl transferase, family 2
ANACY_RS15875	COG1216	Glycosyl transferase, family 2
ANACY_RS15890	COG1215	transferase activity, transferring glycosyl groups
ANACY_RS15895	COG1215	transferase activity, transferring glycosyl groups
ANACY_RS15905	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ANACY_RS15910	COG0457	Tetratricopeptide repeat
ANACY_RS15915	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ANACY_RS15925	COG0739	heme binding
ANACY_RS15930	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ANACY_RS15935	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ANACY_RS15940	COG0542	response to heat
ANACY_RS15970	COG2081	HI0933 family
ANACY_RS15985	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ANACY_RS15990	COG2831	hemolysin activation secretion protein
ANACY_RS16000	COG0312	modulator of DNA gyrase
ANACY_RS16005	COG0312	modulator of DNA gyrase
ANACY_RS16040	COG2244	polysaccharide biosynthetic process
ANACY_RS16045	COG1215	transferase activity, transferring glycosyl groups
ANACY_RS16075	COG1366	Belongs to the anti-sigma-factor antagonist family
ANACY_RS16080	COG0745	RESPONSE REGULATOR receiver
ANACY_RS16085	COG5002	protein histidine kinase activity
ANACY_RS16085	COG2205	protein histidine kinase activity
ANACY_RS16085	COG0784	Response regulator, receiver
ANACY_RS16100	COG0628	permease
ANACY_RS16105	COG0494	nUDIX hydrolase
ANACY_RS16115	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ANACY_RS16125	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
ANACY_RS16145	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ANACY_RS16175	COG1132	(ABC) transporter
ANACY_RS16195	COG3118	belongs to the thioredoxin family
ANACY_RS16220	COG1733	regulation of RNA biosynthetic process
ANACY_RS16235	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ANACY_RS16250	COG0443	Heat shock 70 kDa protein
ANACY_RS16300	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ANACY_RS16305	COG0484	heat shock protein binding
ANACY_RS16315	COG3437	response regulator, receiver
ANACY_RS16315	COG3850	Histidine kinase
ANACY_RS16315	COG2205	protein histidine kinase activity
ANACY_RS16315	COG4999	Histidine kinase
ANACY_RS16325	COG0481	GTPase activity
ANACY_RS16360	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ANACY_RS16365	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ANACY_RS16370	COG0848	biopolymer transport protein
ANACY_RS16385	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
ANACY_RS16395	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ANACY_RS16400	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ANACY_RS16405	COG5002	protein histidine kinase activity
ANACY_RS16420	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ANACY_RS16430	COG3878	Protein conserved in bacteria
ANACY_RS16440	COG0450	alkyl hydroperoxide reductase
ANACY_RS16455	COG0484	heat shock protein binding
ANACY_RS16465	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ANACY_RS16485	COG4636	protein conserved in cyanobacteria
ANACY_RS16515	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ANACY_RS16550	COG0300	oxidoreductase activity
ANACY_RS16555	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ANACY_RS16575	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
ANACY_RS16580	COG4251	negative regulation of phosphorylation
ANACY_RS16590	COG2205	protein histidine kinase activity
ANACY_RS16595	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ANACY_RS16610	COG0572	uridine kinase
ANACY_RS16615	COG4251	negative regulation of phosphorylation
ANACY_RS16620	COG5001	Diguanylate cyclase
ANACY_RS16620	COG4251	negative regulation of phosphorylation
ANACY_RS16620	COG3706	GGDEF domain
ANACY_RS16620	COG2203	Gaf domain
ANACY_RS16625	COG2203	Gaf domain
ANACY_RS16625	COG3706	GGDEF domain
ANACY_RS16625	COG5001	Diguanylate cyclase
ANACY_RS16625	COG4251	negative regulation of phosphorylation
ANACY_RS16630	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ANACY_RS16635	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ANACY_RS16640	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ANACY_RS16650	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ANACY_RS16655	COG2124	cytochrome p450
ANACY_RS16685	COG0012	GTP binding
ANACY_RS16690	COG2815	serine threonine protein kinase
ANACY_RS16690	COG0515	serine threonine protein kinase
ANACY_RS16700	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ANACY_RS16715	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ANACY_RS16725	COG0432	Pfam Uncharacterised protein family UPF0047
ANACY_RS16735	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ANACY_RS16750	COG0515	serine threonine protein kinase
ANACY_RS16755	COG0515	serine threonine protein kinase
ANACY_RS16790	COG1649	PFAM Uncharacterised BCR, COG1649
ANACY_RS16795	COG0402	S-adenosylhomocysteine deaminase activity
ANACY_RS16815	COG0395	ABC-type sugar transport system, permease component
ANACY_RS16820	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
ANACY_RS16825	COG5322	oxidoreductase activity
ANACY_RS16830	COG0825	malonyl-CoA metabolic process
ANACY_RS16835	COG0300	oxidoreductase activity
ANACY_RS16840	COG0302	gtp cyclohydrolase
ANACY_RS16855	COG0135	phosphoribosylanthranilate isomerase activity
ANACY_RS16865	COG1994	Peptidase M50
ANACY_RS16865	COG0517	IMP dehydrogenase activity
ANACY_RS16875	COG0739	heme binding
ANACY_RS16885	COG1388	LysM domain
ANACY_RS16885	COG1376	ErfK ybiS ycfS ynhG family protein
ANACY_RS16890	COG1595	DNA-templated transcription, initiation
ANACY_RS16900	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ANACY_RS16910	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ANACY_RS16915	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ANACY_RS16915	COG0515	serine threonine protein kinase
ANACY_RS16925	COG0495	leucyl-tRNA aminoacylation
ANACY_RS16970	COG0305	Participates in initiation and elongation during chromosome replication
ANACY_RS16970	COG1372	Participates in initiation and elongation during chromosome replication
ANACY_RS16975	COG0359	binds to the 23S rRNA
ANACY_RS16980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ANACY_RS17000	COG1132	(ABC) transporter
ANACY_RS17005	COG0438	transferase activity, transferring glycosyl groups
ANACY_RS17030	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ANACY_RS17035	COG0308	aminopeptidase N
ANACY_RS17090	COG0408	coproporphyrinogen oxidase activity
ANACY_RS17095	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
ANACY_RS17130	COG3688	RNA-binding protein containing a PIN domain
ANACY_RS17135	COG1122	ATPase activity
ANACY_RS17150	COG3659	wide pore channel activity
ANACY_RS17155	COG1959	2 iron, 2 sulfur cluster binding
ANACY_RS17160	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ANACY_RS17165	COG0484	heat shock protein binding
ANACY_RS17200	COG2226	methyltransferase
ANACY_RS17205	COG2045	Belongs to the ComB family
ANACY_RS17215	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ANACY_RS17225	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
ANACY_RS17230	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
ANACY_RS17245	COG1192	Involved in chromosome partitioning
ANACY_RS17280	COG0488	(ABC) transporter
ANACY_RS17295	COG0725	ABC transporter, periplasmic molybdate-binding protein
ANACY_RS17310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ANACY_RS17340	COG1357	PFAM Pentapeptide repeats (8 copies)
ANACY_RS17340	COG0515	serine threonine protein kinase
ANACY_RS17345	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ANACY_RS17350	COG0140	phosphoribosyl-ATP diphosphatase activity
ANACY_RS17350	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ANACY_RS17365	COG2154	pterin-4-alpha-carbinolamine dehydratase
ANACY_RS17400	COG1487	ribonuclease activity
ANACY_RS17455	COG3206	protein involved in exopolysaccharide biosynthesis
ANACY_RS17455	COG0489	protein tyrosine kinase activity
ANACY_RS17460	COG0745	RESPONSE REGULATOR receiver
ANACY_RS17470	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
ANACY_RS17475	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ANACY_RS17480	COG1943	Transposase
ANACY_RS17515	COG0752	glycyl-tRNA synthetase alpha subunit
ANACY_RS17550	COG1070	Carbohydrate kinase
ANACY_RS17575	COG0625	glutathione transferase activity
ANACY_RS17580	COG1666	GTP binding
ANACY_RS17595	COG0857	belongs to the CobB CobQ family
ANACY_RS17605	COG1215	transferase activity, transferring glycosyl groups
ANACY_RS17655	COG1959	2 iron, 2 sulfur cluster binding
ANACY_RS17660	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
ANACY_RS17665	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ANACY_RS17675	COG0784	Response regulator, receiver
ANACY_RS17680	COG4251	negative regulation of phosphorylation
ANACY_RS17690	COG0314	molybdopterin synthase activity
ANACY_RS17705	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ANACY_RS17765	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ANACY_RS17770	COG0134	indole-3-glycerol-phosphate synthase activity
ANACY_RS17800	COG1012	belongs to the aldehyde dehydrogenase family
ANACY_RS17835	COG1830	Aldolase
ANACY_RS17845	COG2267	carboxylic ester hydrolase activity
ANACY_RS17850	COG1361	Conserved repeat domain
ANACY_RS17855	COG0668	transmembrane transport
ANACY_RS17860	COG0123	including yeast histone deacetylase and acetoin utilization protein
ANACY_RS17895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ANACY_RS17920	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ANACY_RS17925	COG0438	transferase activity, transferring glycosyl groups
ANACY_RS17930	COG1215	transferase activity, transferring glycosyl groups
ANACY_RS17940	COG1192	Involved in chromosome partitioning
ANACY_RS17945	COG1192	Involved in chromosome partitioning
ANACY_RS17955	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ANACY_RS18000	COG0587	DNA-directed DNA polymerase activity
ANACY_RS18015	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ANACY_RS18015	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ANACY_RS18025	COG0596	Alpha beta hydrolase
ANACY_RS18050	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ANACY_RS18055	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
ANACY_RS18065	COG0505	Belongs to the CarA family
ANACY_RS18085	COG0784	Response regulator, receiver
ANACY_RS18085	COG5002	protein histidine kinase activity
ANACY_RS18090	COG0328	RNA-DNA hybrid ribonuclease activity
ANACY_RS18100	COG1040	competence protein
ANACY_RS18110	COG1196	nuclear chromosome segregation
ANACY_RS18175	COG0438	transferase activity, transferring glycosyl groups
ANACY_RS18195	COG0492	ferredoxin-NADP+ reductase activity
ANACY_RS18275	COG0358	DNA primase activity
ANACY_RS18290	COG0784	Response regulator, receiver
ANACY_RS18300	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ANACY_RS18305	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
ANACY_RS18315	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ANACY_RS18345	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ANACY_RS18365	COG4245	von Willebrand factor, type A
ANACY_RS18370	COG0512	Glutamine amidotransferase of anthranilate synthase
ANACY_RS18370	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ANACY_RS18385	COG0534	Mate efflux family protein
ANACY_RS18400	COG0077	Prephenate dehydratase
ANACY_RS18400	COG1605	Chorismate mutase
ANACY_RS18425	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ANACY_RS18450	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ANACY_RS18470	COG1429	ligase activity, forming nitrogen-metal bonds
ANACY_RS18495	COG0811	peptide transport
ANACY_RS18500	COG0848	biopolymer transport protein
ANACY_RS18505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ANACY_RS18510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ANACY_RS18515	COG1120	ATPase activity
ANACY_RS18540	COG0675	Transposase, IS605 OrfB family
ANACY_RS18555	COG0811	peptide transport
ANACY_RS18560	COG0848	biopolymer transport protein
ANACY_RS18585	COG0408	coproporphyrinogen oxidase activity
ANACY_RS18595	COG0489	protein tyrosine kinase activity
ANACY_RS18600	COG0772	Belongs to the SEDS family
ANACY_RS18615	COG0475	glutathione-regulated potassium exporter activity
ANACY_RS18615	COG0589	response to stress
ANACY_RS18620	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ANACY_RS18625	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ANACY_RS18635	COG0489	protein tyrosine kinase activity
ANACY_RS18650	COG0438	transferase activity, transferring glycosyl groups
ANACY_RS18675	COG2273	Hydrolase Family 16
ANACY_RS18675	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
ANACY_RS18685	COG0110	maltose O-acetyltransferase activity
ANACY_RS18695	COG0463	Glycosyl transferase, family 2
ANACY_RS18700	COG2327	Polysaccharide pyruvyl transferase
ANACY_RS18715	COG0438	transferase activity, transferring glycosyl groups
ANACY_RS18735	COG1215	transferase activity, transferring glycosyl groups
ANACY_RS18750	COG0529	Catalyzes the synthesis of activated sulfate
ANACY_RS18770	COG1058	Belongs to the CinA family
ANACY_RS18770	COG1546	Belongs to the CinA family
ANACY_RS18775	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ANACY_RS18780	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ANACY_RS18800	COG0360	Binds together with S18 to 16S ribosomal RNA
ANACY_RS18815	COG0586	Pfam SNARE associated Golgi protein
ANACY_RS18820	COG0137	argininosuccinate synthase activity
ANACY_RS18845	COG1216	Glycosyl transferase, family 2
ANACY_RS18870	COG0052	Belongs to the universal ribosomal protein uS2 family
ANACY_RS18880	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ANACY_RS18890	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ANACY_RS18895	COG4636	protein conserved in cyanobacteria
ANACY_RS18900	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ANACY_RS18910	COG0463	Glycosyl transferase, family 2
ANACY_RS18915	COG2814	Major facilitator Superfamily
ANACY_RS18925	COG0315	cyclic pyranopterin monophosphate synthase activity
ANACY_RS18940	COG2204	response regulator
ANACY_RS18995	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
ANACY_RS19005	COG5398	heme oxygenase
ANACY_RS19010	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ANACY_RS19020	COG0438	transferase activity, transferring glycosyl groups
ANACY_RS19030	COG0438	transferase activity, transferring glycosyl groups
ANACY_RS19035	COG0438	transferase activity, transferring glycosyl groups
ANACY_RS19040	COG0450	alkyl hydroperoxide reductase
ANACY_RS19105	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
ANACY_RS19110	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
ANACY_RS19145	COG0354	folic acid binding
ANACY_RS19165	COG1562	ergosterol biosynthetic process
ANACY_RS19170	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
ANACY_RS19170	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ANACY_RS19175	COG1472	Belongs to the glycosyl hydrolase 3 family
ANACY_RS19185	COG2189	Belongs to the N(4) N(6)-methyltransferase family
ANACY_RS19195	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ANACY_RS19200	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ANACY_RS19215	COG1662	PFAM IS1 transposase
ANACY_RS19230	COG2203	Gaf domain
ANACY_RS19230	COG3706	GGDEF domain
ANACY_RS19230	COG5001	Diguanylate cyclase
ANACY_RS19230	COG4251	negative regulation of phosphorylation
ANACY_RS19235	COG0784	Response regulator, receiver
ANACY_RS19235	COG2205	protein histidine kinase activity
ANACY_RS19250	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ANACY_RS19255	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ANACY_RS19295	COG0330	HflC and HflK could
ANACY_RS19305	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ANACY_RS19310	COG0047	phosphoribosylformylglycinamidine synthase activity
ANACY_RS19330	COG0515	serine threonine protein kinase
ANACY_RS19335	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ANACY_RS19340	COG1381	Involved in DNA repair and RecF pathway recombination
ANACY_RS19350	COG0438	transferase activity, transferring glycosyl groups
ANACY_RS19360	COG0488	(ABC) transporter
ANACY_RS19365	COG0475	glutathione-regulated potassium exporter activity
ANACY_RS19400	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ANACY_RS19405	COG0088	Forms part of the polypeptide exit tunnel
ANACY_RS19410	COG0089	rRNA binding
ANACY_RS19415	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ANACY_RS19420	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ANACY_RS19425	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ANACY_RS19430	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ANACY_RS19435	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ANACY_RS19440	COG0255	Belongs to the universal ribosomal protein uL29 family
ANACY_RS19445	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ANACY_RS19450	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ANACY_RS19455	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ANACY_RS19460	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ANACY_RS19465	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ANACY_RS19470	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ANACY_RS19475	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ANACY_RS19480	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ANACY_RS19485	COG0200	Binds to the 23S rRNA
ANACY_RS19490	COG0201	protein transport
ANACY_RS19495	COG0563	adenylate kinase activity
ANACY_RS19500	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ANACY_RS19505	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ANACY_RS19510	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ANACY_RS19515	COG0202	RNA polymerase activity
ANACY_RS19520	COG0203	ribosomal protein L17
ANACY_RS19525	COG0101	tRNA pseudouridine synthase activity
ANACY_RS19530	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ANACY_RS19535	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ANACY_RS19540	COG0254	rRNA binding
ANACY_RS19545	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ANACY_RS19565	COG1002	Type II restriction enzyme, methylase subunits
ANACY_RS19595	COG1515	deoxyribonuclease V activity
ANACY_RS19600	COG0330	HflC and HflK could
ANACY_RS19605	COG0571	ribonuclease III activity
ANACY_RS19615	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ANACY_RS19620	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ANACY_RS19625	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ANACY_RS19630	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ANACY_RS19635	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ANACY_RS19640	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ANACY_RS19655	COG0438	transferase activity, transferring glycosyl groups
ANACY_RS19750	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ANACY_RS19765	COG5002	protein histidine kinase activity
ANACY_RS19805	COG2337	Toxic component of a toxin-antitoxin (TA) module
ANACY_RS19820	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ANACY_RS19915	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ANACY_RS19945	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ANACY_RS19980	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ANACY_RS20015	COG0799	negative regulation of ribosome biogenesis
ANACY_RS20020	COG0297	glycogen (starch) synthase activity
ANACY_RS20030	COG0602	queuosine metabolic process
ANACY_RS20045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ANACY_RS20050	COG4597	amino acid ABC transporter
ANACY_RS20055	COG0765	amino acid transport
ANACY_RS20060	COG1126	abc transporter atp-binding protein
ANACY_RS20100	COG0322	excinuclease ABC activity
ANACY_RS20120	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
ANACY_RS20130	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
ANACY_RS20170	COG1120	ATPase activity
ANACY_RS20175	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ANACY_RS20200	COG1858	cytochrome C peroxidase
ANACY_RS20210	COG4771	TonB-dependent receptor
ANACY_RS20305	COG0535	radical SAM domain protein
ANACY_RS20340	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ANACY_RS20345	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ANACY_RS20380	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
ANACY_RS20385	COG0519	Catalyzes the synthesis of GMP from XMP
ANACY_RS20385	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ANACY_RS20390	COG5002	protein histidine kinase activity
ANACY_RS20395	COG0784	Response regulator, receiver
ANACY_RS20400	COG4251	negative regulation of phosphorylation
ANACY_RS20410	COG1230	cation diffusion facilitator family transporter
ANACY_RS20425	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ANACY_RS20445	COG0009	L-threonylcarbamoyladenylate synthase
ANACY_RS20450	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
ANACY_RS20470	COG4636	protein conserved in cyanobacteria
ANACY_RS20485	COG0159	tryptophan synthase activity
ANACY_RS20495	COG0515	serine threonine protein kinase
ANACY_RS20515	COG2239	Acts as a magnesium transporter
ANACY_RS20520	COG0540	Belongs to the ATCase OTCase family
ANACY_RS20540	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ANACY_RS20560	COG0443	Heat shock 70 kDa protein
ANACY_RS20580	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ANACY_RS20585	COG0681	Belongs to the peptidase S26 family
ANACY_RS20600	COG0484	heat shock protein binding
ANACY_RS20610	COG2048	Heterodisulfide reductase, subunit B
ANACY_RS20615	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ANACY_RS20620	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ANACY_RS20625	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ANACY_RS20630	COG2205	protein histidine kinase activity
ANACY_RS20630	COG0784	Response regulator, receiver
ANACY_RS20630	COG5002	protein histidine kinase activity
ANACY_RS20640	COG2205	protein histidine kinase activity
ANACY_RS20655	COG3693	PFAM glycoside hydrolase, family 10
ANACY_RS20675	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ANACY_RS20680	COG0590	tRNA wobble adenosine to inosine editing
ANACY_RS20710	COG2197	response regulator
ANACY_RS20715	COG4585	Histidine kinase
ANACY_RS20730	COG0534	Mate efflux family protein
ANACY_RS20740	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ANACY_RS20750	COG2326	polyphosphate kinase activity
ANACY_RS20780	COG0745	RESPONSE REGULATOR receiver
ANACY_RS20785	COG0745	RESPONSE REGULATOR receiver
ANACY_RS20790	COG0574	Belongs to the PEP-utilizing enzyme family
ANACY_RS20790	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ANACY_RS20800	COG0167	dihydroorotate dehydrogenase activity
ANACY_RS20805	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ANACY_RS20805	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ANACY_RS20805	COG1013	pyruvate-flavodoxin oxidoreductase activity
ANACY_RS20805	COG0674	pyruvate-flavodoxin oxidoreductase activity
ANACY_RS20915	COG0438	transferase activity, transferring glycosyl groups
ANACY_RS21015	COG3259	Nickel-dependent hydrogenase
ANACY_RS21025	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ANACY_RS21050	COG0589	response to stress
ANACY_RS21055	COG1132	(ABC) transporter
ANACY_RS21060	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
ANACY_RS21085	COG2226	methyltransferase
ANACY_RS21105	COG0811	peptide transport
ANACY_RS21115	COG1136	(ABC) transporter
ANACY_RS21130	COG1309	transcriptional regulator
ANACY_RS21135	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ANACY_RS21150	COG0589	response to stress
ANACY_RS21165	COG3852	Histidine kinase
ANACY_RS21170	COG3237	CsbD-like
ANACY_RS21175	COG3237	CsbD-like
ANACY_RS21195	COG0484	heat shock protein binding
ANACY_RS21210	COG1253	flavin adenine dinucleotide binding
ANACY_RS21215	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ANACY_RS21220	COG0673	inositol 2-dehydrogenase activity
ANACY_RS21225	COG0586	Pfam SNARE associated Golgi protein
ANACY_RS21245	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ANACY_RS21255	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ANACY_RS21260	COG3781	membrane
ANACY_RS21265	COG2234	aminopeptidase activity
ANACY_RS21270	COG0443	Heat shock 70 kDa protein
ANACY_RS21275	COG0484	heat shock protein binding
ANACY_RS21280	COG0484	heat shock protein binding
ANACY_RS21290	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ANACY_RS21295	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
ANACY_RS21300	COG0019	diaminopimelate decarboxylase activity
ANACY_RS21310	COG0542	response to heat
ANACY_RS21315	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
ANACY_RS21325	COG0343	queuine tRNA-ribosyltransferase activity
ANACY_RS21345	COG1216	Glycosyl transferase, family 2
ANACY_RS21375	COG0339	signal peptide processing
ANACY_RS21385	COG1254	Belongs to the acylphosphatase family
ANACY_RS21410	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ANACY_RS21410	COG0189	ligase activity
ANACY_RS21420	COG2091	lysine biosynthetic process via aminoadipic acid
ANACY_RS21425	COG0429	hydrolase of the alpha beta-hydrolase fold
ANACY_RS21430	COG0745	RESPONSE REGULATOR receiver
ANACY_RS21445	COG2442	InterPro IPR007367
ANACY_RS21490	COG1748	Saccharopine dehydrogenase
ANACY_RS21500	COG1459	type II secretion system
ANACY_RS21510	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ANACY_RS21515	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ANACY_RS21520	COG0443	Heat shock 70 kDa protein
ANACY_RS21525	COG0484	heat shock protein binding
ANACY_RS21535	COG1162	GTPase activity
ANACY_RS21540	COG1543	Belongs to the glycosyl hydrolase 57 family
ANACY_RS21550	COG0515	serine threonine protein kinase
ANACY_RS21550	COG2815	serine threonine protein kinase
ANACY_RS21555	COG1253	flavin adenine dinucleotide binding
ANACY_RS21580	COG2066	Belongs to the glutaminase family
ANACY_RS21590	COG2885	chlorophyll binding
ANACY_RS21620	COG1214	PFAM Peptidase M22, glycoprotease
ANACY_RS21630	COG0617	tRNA 3'-terminal CCA addition
ANACY_RS21635	COG0784	Response regulator, receiver
ANACY_RS21635	COG2205	protein histidine kinase activity
ANACY_RS21645	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ANACY_RS21645	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ANACY_RS21660	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ANACY_RS21665	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ANACY_RS21675	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ANACY_RS21690	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ANACY_RS21710	COG5002	protein histidine kinase activity
ANACY_RS21720	COG2205	protein histidine kinase activity
ANACY_RS21730	COG1175	transmembrane transport
ANACY_RS21745	COG5001	Diguanylate cyclase
ANACY_RS21745	COG4251	negative regulation of phosphorylation
ANACY_RS21745	COG2203	Gaf domain
ANACY_RS21745	COG3706	GGDEF domain
ANACY_RS21770	COG3956	TIGRFAM MazG family protein
ANACY_RS21775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ANACY_RS21815	COG0025	NhaP-type Na H and K H
ANACY_RS21820	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ANACY_RS21835	COG1169	isochorismate synthase
ANACY_RS21840	COG1575	Belongs to the MenA family. Type 1 subfamily
ANACY_RS21850	COG0318	PFAM AMP-dependent synthetase and ligase
ANACY_RS21855	COG0824	Thioesterase
ANACY_RS21910	COG0606	chelatase, subunit chli
ANACY_RS21920	COG0632	four-way junction helicase activity
ANACY_RS21925	COG0156	8-amino-7-oxononanoate synthase activity
ANACY_RS21930	COG0004	ammonium transporteR
ANACY_RS21935	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ANACY_RS21940	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ANACY_RS21950	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ANACY_RS21990	COG0612	Peptidase, M16
ANACY_RS22005	COG1201	RNA secondary structure unwinding
ANACY_RS22010	COG3266	domain, Protein
ANACY_RS22010	COG0515	serine threonine protein kinase
ANACY_RS22035	COG0574	Belongs to the PEP-utilizing enzyme family
ANACY_RS22035	COG3848	Pyruvate phosphate dikinase
ANACY_RS22040	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ANACY_RS22045	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ANACY_RS22050	COG1116	anion transmembrane transporter activity
ANACY_RS22050	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ANACY_RS22055	COG1116	anion transmembrane transporter activity
ANACY_RS22060	COG1028	Short-chain dehydrogenase reductase Sdr
ANACY_RS22065	COG0501	Belongs to the peptidase M48B family
ANACY_RS22090	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ANACY_RS22100	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ANACY_RS22135	COG0577	efflux transmembrane transporter activity
ANACY_RS22135	COG1136	(ABC) transporter
ANACY_RS22180	COG0424	maF-like protein
ANACY_RS22190	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ANACY_RS22200	COG4638	Rieske (2fe-2S)
ANACY_RS22210	COG0095	Lipoate-protein ligase
ANACY_RS22215	COG0138	bifunctional purine biosynthesis protein purh
ANACY_RS22220	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ANACY_RS22260	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
ANACY_RS22285	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ANACY_RS22290	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ANACY_RS22295	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ANACY_RS22325	COG1960	acyl-CoA dehydrogenase activity
ANACY_RS22330	COG3321	synthase
ANACY_RS22330	COG0300	oxidoreductase activity
ANACY_RS22330	COG4221	oxidoreductase activity
ANACY_RS22330	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ANACY_RS22335	COG1696	Membrane protein involved in D-alanine export
ANACY_RS22345	COG1252	NADH dehydrogenase
ANACY_RS22355	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ANACY_RS22365	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ANACY_RS22380	COG2852	Protein conserved in bacteria
ANACY_RS22405	COG3852	Histidine kinase
ANACY_RS22410	COG0351	phosphomethylpyrimidine kinase
ANACY_RS22450	COG0564	pseudouridine synthase activity
ANACY_RS22455	COG3852	Histidine kinase
ANACY_RS22490	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ANACY_RS22505	COG0438	transferase activity, transferring glycosyl groups
ANACY_RS22510	COG1177	transmembrane transport
ANACY_RS22520	COG0745	RESPONSE REGULATOR receiver
ANACY_RS22525	COG0745	RESPONSE REGULATOR receiver
ANACY_RS22535	COG0784	Response regulator, receiver
ANACY_RS22540	COG4251	negative regulation of phosphorylation
ANACY_RS22565	COG4689	acetoacetate decarboxylase
ANACY_RS22570	COG1217	gtp-binding protein TYPA
ANACY_RS22590	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ANACY_RS22595	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ANACY_RS22600	COG0515	serine threonine protein kinase
ANACY_RS22605	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ANACY_RS22620	COG1473	amidohydrolase
ANACY_RS22625	COG4242	Belongs to the peptidase S51 family
ANACY_RS22635	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ANACY_RS22660	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ANACY_RS22665	COG1253	flavin adenine dinucleotide binding
ANACY_RS22700	COG4802	Ferredoxin thioredoxin reductase catalytic beta chain
ANACY_RS22740	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ANACY_RS22740	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
ANACY_RS22755	COG1836	PFAM Integral membrane protein DUF92
ANACY_RS22790	COG2022	thiamine diphosphate biosynthetic process
ANACY_RS22790	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ANACY_RS22795	COG0445	tRNA wobble uridine modification
ANACY_RS22820	COG0788	formyltetrahydrofolate deformylase activity
ANACY_RS22840	COG1131	(ABC) transporter
ANACY_RS22860	COG0352	thiamine-phosphate diphosphorylase activity
ANACY_RS22895	COG0515	serine threonine protein kinase
ANACY_RS22900	COG0616	signal peptide processing
ANACY_RS22905	COG1304	FMN binding
ANACY_RS22930	COG3852	Histidine kinase
ANACY_RS22935	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ANACY_RS22940	COG1357	PFAM Pentapeptide repeats (8 copies)
ANACY_RS22940	COG0515	serine threonine protein kinase
ANACY_RS22945	COG0515	serine threonine protein kinase
ANACY_RS22945	COG1357	PFAM Pentapeptide repeats (8 copies)
ANACY_RS22965	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ANACY_RS22970	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ANACY_RS22980	COG1116	anion transmembrane transporter activity
ANACY_RS22985	COG1116	anion transmembrane transporter activity
ANACY_RS22985	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ANACY_RS22990	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ANACY_RS22995	COG0784	Response regulator, receiver
ANACY_RS22995	COG5002	protein histidine kinase activity
ANACY_RS23000	COG0571	ribonuclease III activity
ANACY_RS23025	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
ANACY_RS23025	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
ANACY_RS23050	COG0670	Belongs to the BI1 family
ANACY_RS23055	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ANACY_RS23060	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ANACY_RS23065	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ANACY_RS23070	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ANACY_RS23070	COG0512	Glutamine amidotransferase of anthranilate synthase
ANACY_RS23095	COG0006	proline dipeptidase activity
ANACY_RS23110	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ANACY_RS23115	COG1899	peptidyl-lysine modification to peptidyl-hypusine
ANACY_RS23120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ANACY_RS23135	COG4249	Peptidase C14 caspase catalytic subunit p20
ANACY_RS23135	COG2319	Wd-40 repeat
ANACY_RS23140	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ANACY_RS23150	COG0644	oxidoreductase
ANACY_RS23200	COG2226	methyltransferase
ANACY_RS23205	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ANACY_RS23215	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ANACY_RS23225	COG3852	Histidine kinase
ANACY_RS23235	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ANACY_RS23250	COG1950	PFAM Membrane protein of
ANACY_RS23260	COG0612	Peptidase, M16
ANACY_RS23265	COG0612	Peptidase, M16
ANACY_RS23270	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ANACY_RS23275	COG1357	PFAM Pentapeptide repeats (8 copies)
ANACY_RS23285	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ANACY_RS23305	COG0175	sulfate reduction
ANACY_RS23315	COG0321	lipoyl(octanoyl) transferase activity
ANACY_RS23320	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ANACY_RS23325	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ANACY_RS23355	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ANACY_RS23375	COG0768	penicillin binding
ANACY_RS23400	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ANACY_RS23420	COG0748	coenzyme F420 binding
ANACY_RS23445	COG2197	response regulator
ANACY_RS23455	COG3854	ATPases associated with a variety of cellular activities
ANACY_RS23465	COG0459	protein refolding
ANACY_RS23470	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ANACY_RS23475	COG1028	Short-chain dehydrogenase reductase Sdr
ANACY_RS23480	COG0702	epimerase
ANACY_RS23495	COG1773	rubredoxin
ANACY_RS23495	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ANACY_RS23505	COG0438	transferase activity, transferring glycosyl groups
ANACY_RS23555	COG1035	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
ANACY_RS23565	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
ANACY_RS23575	COG3239	Fatty acid desaturase
ANACY_RS23580	COG3239	Fatty acid desaturase
ANACY_RS23600	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ANACY_RS23615	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ANACY_RS23625	COG0517	IMP dehydrogenase activity
ANACY_RS23625	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ANACY_RS23625	COG0617	tRNA 3'-terminal CCA addition
ANACY_RS23635	COG1357	PFAM Pentapeptide repeats (8 copies)
ANACY_RS23635	COG0515	serine threonine protein kinase
ANACY_RS23645	COG1940	carbohydrate kinase activity
ANACY_RS23670	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
ANACY_RS23680	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ANACY_RS23685	COG0109	protoheme IX farnesyltransferase activity
ANACY_RS23695	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ANACY_RS23700	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ANACY_RS23705	COG1845	cytochrome c oxidase, subunit III
ANACY_RS23730	COG1480	7TM receptor with intracellular HD hydrolase
ANACY_RS23740	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ANACY_RS23750	COG1754	DNA topoisomerase type I activity
ANACY_RS23750	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ANACY_RS23780	COG1007	ATP synthesis coupled electron transport
ANACY_RS23785	COG0745	RESPONSE REGULATOR receiver
ANACY_RS23790	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ANACY_RS23805	COG2205	protein histidine kinase activity
ANACY_RS23805	COG0784	Response regulator, receiver
ANACY_RS23805	COG2198	Histidine kinase
ANACY_RS23815	COG1606	tRNA processing
ANACY_RS23835	COG3852	Histidine kinase
ANACY_RS23845	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ANACY_RS23845	COG0758	DNA mediated transformation
ANACY_RS23865	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ANACY_RS23875	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ANACY_RS23910	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ANACY_RS23915	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ANACY_RS23920	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
ANACY_RS23940	COG1361	Conserved repeat domain
ANACY_RS23945	COG4636	protein conserved in cyanobacteria
ANACY_RS23975	COG0419	ATPase involved in DNA repair
ANACY_RS23990	COG2223	nitrite transmembrane transporter activity
ANACY_RS24000	COG0456	acetyltransferase
ANACY_RS24010	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ANACY_RS24020	COG3300	MHYT domain
ANACY_RS24020	COG5001	Diguanylate cyclase
ANACY_RS24035	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ANACY_RS24040	COG1968	undecaprenyl-diphosphatase activity
ANACY_RS24050	COG1555	photosystem II stabilization
ANACY_RS24055	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ANACY_RS24070	COG4243	Vitamin k epoxide reductase
ANACY_RS24075	COG0434	BtpA family
ANACY_RS24080	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ANACY_RS24085	COG0513	Belongs to the DEAD box helicase family
ANACY_RS24130	COG0483	inositol monophosphate 1-phosphatase activity
ANACY_RS24160	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ANACY_RS24200	COG0562	UDP-galactopyranose mutase
ANACY_RS24215	COG1215	transferase activity, transferring glycosyl groups
ANACY_RS24245	COG0438	transferase activity, transferring glycosyl groups
ANACY_RS24250	COG0469	pyruvate kinase activity
ANACY_RS24290	COG0616	signal peptide processing
ANACY_RS24300	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ANACY_RS24315	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ANACY_RS24320	COG1160	GTP binding
ANACY_RS24325	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ANACY_RS24330	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ANACY_RS24360	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ANACY_RS24370	COG2226	methyltransferase
ANACY_RS24400	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ANACY_RS24405	COG5002	protein histidine kinase activity
ANACY_RS24405	COG0784	Response regulator, receiver
ANACY_RS24405	COG2205	protein histidine kinase activity
ANACY_RS24410	COG0745	RESPONSE REGULATOR receiver
ANACY_RS24415	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ANACY_RS24420	COG0398	Pfam SNARE associated Golgi protein
ANACY_RS24425	COG0398	Pfam SNARE associated Golgi protein
ANACY_RS24440	COG0436	Aminotransferase
ANACY_RS24460	COG0515	serine threonine protein kinase
ANACY_RS24465	COG0515	serine threonine protein kinase
ANACY_RS24465	COG3266	domain, Protein
ANACY_RS24525	COG0584	glycerophosphoryl diester phosphodiesterase
ANACY_RS24560	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ANACY_RS24575	COG1120	ATPase activity
ANACY_RS24615	COG0110	maltose O-acetyltransferase activity
ANACY_RS24625	COG1215	transferase activity, transferring glycosyl groups
ANACY_RS24670	COG2197	response regulator
ANACY_RS24680	COG1234	tRNA 3'-trailer cleavage
ANACY_RS24685	COG0489	protein tyrosine kinase activity
ANACY_RS24690	COG2385	sporulation resulting in formation of a cellular spore
ANACY_RS24730	COG0667	Aldo Keto reductase
ANACY_RS24750	COG0542	response to heat
ANACY_RS24765	COG1127	ABC transporter
ANACY_RS24770	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ANACY_RS24780	COG0539	negative regulation of cytoplasmic translation
ANACY_RS24795	COG2161	toxin-antitoxin pair type II binding
ANACY_RS24815	COG0601	transmembrane transport
ANACY_RS24835	COG0443	Heat shock 70 kDa protein
ANACY_RS24860	COG0346	lactoylglutathione lyase activity
ANACY_RS24865	COG0798	PFAM Bile acid sodium symporter
ANACY_RS24875	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ANACY_RS24880	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ANACY_RS24900	COG0436	Aminotransferase
ANACY_RS24905	COG0371	Dehydrogenase
ANACY_RS24915	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
ANACY_RS24940	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ANACY_RS24945	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ANACY_RS24955	COG1074	ATP-dependent DNA helicase activity
ANACY_RS24970	COG2204	response regulator
ANACY_RS24975	COG2226	methyltransferase
ANACY_RS24980	COG4399	Belongs to the UPF0754 family
ANACY_RS24990	COG0686	Belongs to the AlaDH PNT family
ANACY_RS24995	COG3903	Transcriptional regulator
ANACY_RS24995	COG2319	Wd-40 repeat
ANACY_RS25005	COG0673	inositol 2-dehydrogenase activity
ANACY_RS25010	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ANACY_RS25025	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ANACY_RS25025	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ANACY_RS25040	COG2119	membrane
ANACY_RS25110	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ANACY_RS25115	COG0668	transmembrane transport
ANACY_RS25125	COG1049	propionate catabolic process, 2-methylcitrate cycle
ANACY_RS25170	COG0515	serine threonine protein kinase
ANACY_RS25170	COG1357	PFAM Pentapeptide repeats (8 copies)
ANACY_RS25180	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ANACY_RS25190	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ANACY_RS25200	COG0514	ATP-dependent DNA helicase (RecQ)
ANACY_RS25215	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ANACY_RS25220	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ANACY_RS25225	COG1234	tRNA 3'-trailer cleavage
ANACY_RS25230	COG0196	riboflavin kinase activity
ANACY_RS25235	COG0714	Associated with various cellular activities
ANACY_RS25250	COG0653	protein targeting
ANACY_RS25270	COG0419	ATPase involved in DNA repair
ANACY_RS25290	COG0784	Response regulator, receiver
ANACY_RS25305	COG0745	RESPONSE REGULATOR receiver
ANACY_RS25340	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ANACY_RS25360	COG0537	adenosine 5'-monophosphoramidase activity
ANACY_RS25370	COG0438	transferase activity, transferring glycosyl groups
ANACY_RS25375	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ANACY_RS25400	COG1215	transferase activity, transferring glycosyl groups
ANACY_RS25415	COG1619	proteins homologs of microcin C7 resistance protein MccF
ANACY_RS25425	COG0697	spore germination
ANACY_RS25460	COG0516	GMP reductase activity
ANACY_RS25465	COG3118	belongs to the thioredoxin family
ANACY_RS25490	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ANACY_RS25495	COG2267	carboxylic ester hydrolase activity
ANACY_RS25510	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ANACY_RS25530	COG0416	fatty acid biosynthetic process
ANACY_RS25535	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ANACY_RS25545	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ANACY_RS25570	COG0628	permease
ANACY_RS25580	COG2268	Band 7 protein
ANACY_RS25605	COG0539	negative regulation of cytoplasmic translation
ANACY_RS25610	COG0412	Dienelactone hydrolase
ANACY_RS25615	COG2188	Transcriptional regulator
ANACY_RS25620	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ANACY_RS25640	COG1215	transferase activity, transferring glycosyl groups
ANACY_RS25645	COG1657	PFAM Prenyltransferase squalene oxidase
ANACY_RS25660	COG0113	porphobilinogen synthase activity
ANACY_RS25670	COG0523	cobalamin synthesis protein
ANACY_RS25675	COG0302	gtp cyclohydrolase
ANACY_RS25695	COG2003	Belongs to the UPF0758 family
ANACY_RS25700	COG0557	exoribonuclease II activity
ANACY_RS25705	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ANACY_RS25740	COG0303	'Molybdopterin
ANACY_RS25745	COG0534	Mate efflux family protein
ANACY_RS25760	COG1982	Orn Lys Arg decarboxylase major
ANACY_RS25770	COG1032	radical SAM domain protein
ANACY_RS25820	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ANACY_RS25830	COG0415	Belongs to the DNA photolyase family
ANACY_RS25835	COG0753	catalase activity
ANACY_RS25850	COG0297	glycogen (starch) synthase activity
ANACY_RS25855	COG0181	hydroxymethylbilane synthase activity
ANACY_RS25860	COG3706	GGDEF domain
ANACY_RS25870	COG1597	lipid kinase activity
ANACY_RS25870	COG1803	Methylglyoxal synthase
ANACY_RS25880	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ANACY_RS25900	COG0583	DNA-binding transcription factor activity
ANACY_RS25905	COG0129	dihydroxy-acid dehydratase activity
ANACY_RS25925	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ANACY_RS25935	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ANACY_RS25950	COG1487	ribonuclease activity
ANACY_RS25960	COG0126	phosphoglycerate kinase activity
ANACY_RS25965	COG0589	response to stress
ANACY_RS25990	COG1662	PFAM IS1 transposase
ANACY_RS25995	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ANACY_RS26000	COG4956	integral membrane protein (PIN domain superfamily)
ANACY_RS26005	COG0346	lactoylglutathione lyase activity
ANACY_RS26015	COG0792	nuclease activity
ANACY_RS26030	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ANACY_RS26040	COG0569	domain protein
ANACY_RS26045	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ANACY_RS26050	COG2226	methyltransferase
ANACY_RS26055	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ANACY_RS26065	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ANACY_RS26070	COG1587	Uroporphyrinogen-III synthase
ANACY_RS26075	COG0237	dephospho-CoA kinase activity
ANACY_RS26080	COG0784	Response regulator, receiver
ANACY_RS26085	COG4251	negative regulation of phosphorylation
ANACY_RS26145	COG3266	domain, Protein
ANACY_RS26145	COG0515	serine threonine protein kinase
ANACY_RS26150	COG2319	Wd-40 repeat
ANACY_RS26150	COG5635	Nacht domain
ANACY_RS26180	COG1473	amidohydrolase
ANACY_RS26190	COG5592	hemerythrin HHE cation binding domain
ANACY_RS26195	COG1132	(ABC) transporter
ANACY_RS26200	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ANACY_RS26205	COG0678	peroxiredoxin activity
ANACY_RS26230	COG1028	Short-chain dehydrogenase reductase Sdr
ANACY_RS26245	COG0038	chloride channel
ANACY_RS26270	COG2010	Cytochrome c
ANACY_RS26275	COG0742	ribosomal rna small subunit methyltransferase
ANACY_RS26280	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ANACY_RS26285	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
ANACY_RS26295	COG1981	membrane
ANACY_RS26305	COG2267	carboxylic ester hydrolase activity
ANACY_RS26325	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ANACY_RS26330	COG0517	IMP dehydrogenase activity
ANACY_RS26330	COG1994	Peptidase M50
ANACY_RS26345	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
ANACY_RS26375	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ANACY_RS26380	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ANACY_RS26390	COG0484	heat shock protein binding
ANACY_RS26395	COG0740	serine-type endopeptidase activity
ANACY_RS26400	COG0740	serine-type endopeptidase activity
ANACY_RS26415	COG0515	serine threonine protein kinase
ANACY_RS26415	COG3266	domain, Protein
ANACY_RS26420	COG3903	Transcriptional regulator
ANACY_RS26420	COG2319	Wd-40 repeat
ANACY_RS26430	COG1404	Belongs to the peptidase S8 family
ANACY_RS26435	COG2304	oxidoreductase activity
ANACY_RS26440	COG2304	oxidoreductase activity
ANACY_RS26460	COG0066	3-isopropylmalate dehydratase activity
ANACY_RS26465	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ANACY_RS26480	COG0071	Belongs to the small heat shock protein (HSP20) family
ANACY_RS26505	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ANACY_RS26535	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ANACY_RS26550	COG2130	NADP-dependent
ANACY_RS26555	COG0724	RNA recognition motif
ANACY_RS26565	COG0191	fructose-bisphosphate aldolase activity
ANACY_RS26585	COG0842	Transport permease protein
ANACY_RS26620	COG0842	Transport permease protein
ANACY_RS26620	COG1129	ABC transporter
ANACY_RS26625	COG1131	(ABC) transporter
ANACY_RS26630	COG1845	cytochrome c oxidase, subunit III
ANACY_RS26635	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ANACY_RS26640	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ANACY_RS26655	COG3788	relative of glutathione S-transferase, MAPEG superfamily
ANACY_RS26660	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ANACY_RS26670	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ANACY_RS26675	COG3852	Histidine kinase
ANACY_RS26680	COG0625	glutathione transferase activity
ANACY_RS26695	COG2207	Transcriptional regulator
ANACY_RS26710	COG4221	oxidoreductase activity
ANACY_RS26725	COG2815	serine threonine protein kinase
ANACY_RS26725	COG0515	serine threonine protein kinase
ANACY_RS26730	COG1028	Short-chain dehydrogenase reductase Sdr
ANACY_RS26785	COG0745	RESPONSE REGULATOR receiver
ANACY_RS26840	COG2226	methyltransferase
ANACY_RS26875	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ANACY_RS26885	COG1169	isochorismate synthase
ANACY_RS26890	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ANACY_RS26915	COG0513	Belongs to the DEAD box helicase family
ANACY_RS26935	COG0312	modulator of DNA gyrase
ANACY_RS26945	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
ANACY_RS26960	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ANACY_RS26965	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ANACY_RS26985	COG0515	serine threonine protein kinase
ANACY_RS26985	COG1357	PFAM Pentapeptide repeats (8 copies)
ANACY_RS26995	COG0601	transmembrane transport
ANACY_RS27000	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ANACY_RS27025	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ANACY_RS27035	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ANACY_RS27040	COG0573	inorganic phosphate transmembrane transporter activity
ANACY_RS27045	COG0581	inorganic phosphate transmembrane transporter activity
ANACY_RS27050	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ANACY_RS27190	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ANACY_RS27215	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
ANACY_RS27215	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ANACY_RS27220	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ANACY_RS27235	COG3631	Ketosteroid isomerase-related protein
ANACY_RS27240	COG1446	asparaginase
ANACY_RS27250	COG0167	dihydroorotate dehydrogenase activity
ANACY_RS27265	COG2304	oxidoreductase activity
ANACY_RS27300	COG0459	protein refolding
ANACY_RS27305	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ANACY_RS27315	COG0745	RESPONSE REGULATOR receiver
ANACY_RS27320	COG4636	protein conserved in cyanobacteria
ANACY_RS27330	COG0017	Asparaginyl-tRNA synthetase
ANACY_RS27350	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ANACY_RS27360	COG0829	nickel cation binding
ANACY_RS27365	COG0831	urea catabolic process
ANACY_RS27370	COG0832	Belongs to the urease beta subunit family
ANACY_RS27375	COG0804	urea catabolic process
ANACY_RS27390	COG1012	belongs to the aldehyde dehydrogenase family
ANACY_RS27400	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ANACY_RS27405	COG0740	serine-type endopeptidase activity
ANACY_RS27415	COG0544	peptidyl-prolyl cis-trans isomerase activity
ANACY_RS27420	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ANACY_RS27425	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ANACY_RS27430	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ANACY_RS27450	COG1193	negative regulation of DNA recombination
ANACY_RS27485	COG0596	Alpha beta hydrolase
ANACY_RS27490	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ANACY_RS27495	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ANACY_RS27500	COG0010	Belongs to the arginase family
ANACY_RS27525	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ANACY_RS27530	COG3338	carbonate dehydratase activity
ANACY_RS27550	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ANACY_RS27585	COG0717	Belongs to the dCTP deaminase family
ANACY_RS27595	COG0756	dUTP diphosphatase activity
ANACY_RS27610	COG5001	Diguanylate cyclase
ANACY_RS27610	COG2203	Gaf domain
ANACY_RS27610	COG3706	GGDEF domain
ANACY_RS27610	COG4251	negative regulation of phosphorylation
ANACY_RS27630	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ANACY_RS27640	COG0318	PFAM AMP-dependent synthetase and ligase
ANACY_RS27645	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ANACY_RS27650	COG1461	Dihydroxyacetone kinase
ANACY_RS27655	COG2376	Dihydroxyacetone kinase
ANACY_RS27660	COG0242	peptide deformylase activity
ANACY_RS27665	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ANACY_RS28850	COG1301	dicarboxylic acid transport
ANACY_RS29060	COG0384	phenazine biosynthesis protein PhzF
ANACY_RS29300	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ANACY_RS29415	COG0659	secondary active sulfate transmembrane transporter activity
ANACY_RS30120	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ANACY_RS30405	COG2198	Histidine kinase
ANACY_RS30405	COG5002	protein histidine kinase activity
ANACY_RS30405	COG0784	Response regulator, receiver
ANACY_RS30435	COG0784	Response regulator, receiver
ANACY_RS30435	COG2205	protein histidine kinase activity
ANACY_RS30445	COG3852	Histidine kinase
ANACY_RS30455	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ANACY_RS30525	COG3706	GGDEF domain
ANACY_RS30525	COG5001	Diguanylate cyclase
ANACY_RS30525	COG4251	negative regulation of phosphorylation
ANACY_RS30525	COG2203	Gaf domain
ANACY_RS30535	COG2205	protein histidine kinase activity
ANACY_RS30535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ANACY_RS30545	COG2319	Wd-40 repeat
ANACY_RS30545	COG4249	Peptidase C14 caspase catalytic subunit p20
ANACY_RS30570	COG0827	DNA restriction-modification system
ANACY_RS30580	COG1132	(ABC) transporter
ANACY_RS30605	COG4251	negative regulation of phosphorylation
ANACY_RS30610	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ANACY_RS30625	COG2205	protein histidine kinase activity
ANACY_RS30625	COG2202	Pas domain
ANACY_RS30630	COG5002	protein histidine kinase activity
ANACY_RS30665	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ANACY_RS30675	COG0784	Response regulator, receiver
ANACY_RS30675	COG2205	protein histidine kinase activity
ANACY_RS30675	COG5002	protein histidine kinase activity
ANACY_RS30680	COG1366	Belongs to the anti-sigma-factor antagonist family
ANACY_RS30680	COG2202	Pas domain
ANACY_RS30685	COG1216	Glycosyl transferase, family 2
ANACY_RS30690	COG1160	GTP binding
ANACY_RS30705	COG0784	Response regulator, receiver
ANACY_RS30705	COG5002	protein histidine kinase activity
ANACY_RS30730	COG4249	Peptidase C14 caspase catalytic subunit p20
ANACY_RS30730	COG2319	Wd-40 repeat