locus-tag	class	description
EH233_RS00010	COG0242	peptide deformylase activity
EH233_RS00025	COG2217	Heavy metal translocating P-type atpase
EH233_RS00045	COG2095	MarC family integral membrane protein
EH233_RS00055	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EH233_RS00060	COG0438	transferase activity, transferring glycosyl groups
EH233_RS00075	COG1177	transmembrane transport
EH233_RS00080	COG0515	serine threonine protein kinase
EH233_RS00080	COG1357	PFAM Pentapeptide repeats (8 copies)
EH233_RS00120	COG0352	thiamine-phosphate diphosphorylase activity
EH233_RS00140	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EH233_RS00145	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EH233_RS00170	COG2022	thiamine diphosphate biosynthetic process
EH233_RS00170	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EH233_RS00185	COG3224	Antibiotic biosynthesis monooxygenase
EH233_RS00190	COG1335	isochorismatase
EH233_RS00195	COG2319	Wd-40 repeat
EH233_RS00195	COG3903	Transcriptional regulator
EH233_RS00210	COG0330	HflC and HflK could
EH233_RS00220	COG0671	phosphoesterase, PA-phosphatase related
EH233_RS00225	COG0730	response to heat
EH233_RS00235	COG0583	DNA-binding transcription factor activity
EH233_RS00260	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EH233_RS00265	COG1959	2 iron, 2 sulfur cluster binding
EH233_RS00270	COG1045	serine acetyltransferase
EH233_RS00275	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EH233_RS00295	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EH233_RS00305	COG0625	glutathione transferase activity
EH233_RS00310	COG0667	Aldo Keto reductase
EH233_RS00315	COG3491	Belongs to the iron ascorbate-dependent oxidoreductase family
EH233_RS00345	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EH233_RS00350	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EH233_RS00360	COG0644	oxidoreductase
EH233_RS00370	COG0625	glutathione transferase activity
EH233_RS00380	COG0408	coproporphyrinogen oxidase activity
EH233_RS00395	COG1132	(ABC) transporter
EH233_RS00400	COG1252	NADH dehydrogenase
EH233_RS00405	COG4172	Belongs to the ABC transporter superfamily
EH233_RS00425	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EH233_RS00435	COG1122	ATPase activity
EH233_RS00455	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EH233_RS00465	COG0678	peroxiredoxin activity
EH233_RS00465	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EH233_RS00480	COG0697	spore germination
EH233_RS00535	COG4771	TonB-dependent receptor
EH233_RS00585	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EH233_RS00610	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EH233_RS00615	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EH233_RS00660	COG0590	tRNA wobble adenosine to inosine editing
EH233_RS00665	COG0495	leucyl-tRNA aminoacylation
EH233_RS00680	COG1595	DNA-templated transcription, initiation
EH233_RS00690	COG1376	ErfK ybiS ycfS ynhG family protein
EH233_RS00700	COG0741	lytic transglycosylase activity
EH233_RS00700	COG1196	nuclear chromosome segregation
EH233_RS00700	COG0739	heme binding
EH233_RS00710	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EH233_RS00715	COG1619	proteins homologs of microcin C7 resistance protein MccF
EH233_RS00720	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EH233_RS00730	COG1357	PFAM Pentapeptide repeats (8 copies)
EH233_RS00730	COG0515	serine threonine protein kinase
EH233_RS00745	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EH233_RS00755	COG0140	phosphoribosyl-ATP diphosphatase activity
EH233_RS00755	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EH233_RS00770	COG0745	RESPONSE REGULATOR receiver
EH233_RS00785	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
EH233_RS00805	COG2501	S4 domain
EH233_RS00810	COG1028	Short-chain dehydrogenase reductase Sdr
EH233_RS00840	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EH233_RS00845	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EH233_RS00855	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EH233_RS00860	COG0784	Response regulator, receiver
EH233_RS00880	COG0134	indole-3-glycerol-phosphate synthase activity
EH233_RS00890	COG0512	Glutamine amidotransferase of anthranilate synthase
EH233_RS00890	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EH233_RS00905	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EH233_RS00910	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EH233_RS00925	COG0582	viral genome integration into host DNA
EH233_RS00945	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
EH233_RS00960	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EH233_RS00970	COG0432	Pfam Uncharacterised protein family UPF0047
EH233_RS00995	COG2337	Toxic component of a toxin-antitoxin (TA) module
EH233_RS01010	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EH233_RS01025	COG0515	serine threonine protein kinase
EH233_RS01030	COG0515	serine threonine protein kinase
EH233_RS01040	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EH233_RS01050	COG1489	DNA binding
EH233_RS01055	COG3265	gluconokinase activity
EH233_RS01060	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EH233_RS01065	COG1104	cysteine desulfurase activity
EH233_RS01070	COG1357	PFAM Pentapeptide repeats (8 copies)
EH233_RS01070	COG0515	serine threonine protein kinase
EH233_RS01110	COG1472	Belongs to the glycosyl hydrolase 3 family
EH233_RS01125	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
EH233_RS01130	COG0438	transferase activity, transferring glycosyl groups
EH233_RS01135	COG3307	-O-antigen
EH233_RS01140	COG0438	transferase activity, transferring glycosyl groups
EH233_RS01145	COG1442	glycosyl transferase family 8
EH233_RS01145	COG1216	Glycosyl transferase, family 2
EH233_RS01185	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EH233_RS01205	COG0170	dolichyl monophosphate biosynthetic process
EH233_RS01210	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EH233_RS01215	COG1836	PFAM Integral membrane protein DUF92
EH233_RS01230	COG1404	Belongs to the peptidase S8 family
EH233_RS01240	COG1361	Conserved repeat domain
EH233_RS01240	COG2911	Protein conserved in bacteria
EH233_RS01240	COG3266	domain, Protein
EH233_RS01245	COG4636	protein conserved in cyanobacteria
EH233_RS01250	COG1131	(ABC) transporter
EH233_RS01270	COG0788	formyltetrahydrofolate deformylase activity
EH233_RS01275	COG2217	Heavy metal translocating P-type atpase
EH233_RS01295	COG1404	Belongs to the peptidase S8 family
EH233_RS01300	COG0464	growth
EH233_RS01310	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EH233_RS01330	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EH233_RS01330	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EH233_RS01365	COG1857	crispr-associated protein
EH233_RS01405	COG0789	Transcriptional regulator
EH233_RS01410	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EH233_RS01415	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EH233_RS01420	COG3119	arylsulfatase activity
EH233_RS01435	COG5554	nitrogen fixation
EH233_RS01440	COG1433	Dinitrogenase iron-molybdenum cofactor
EH233_RS01440	COG0535	radical SAM domain protein
EH233_RS01445	COG1104	cysteine desulfurase activity
EH233_RS01460	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
EH233_RS01470	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
EH233_RS01480	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
EH233_RS01495	COG5420	small protein containing a coiled-coil domain
EH233_RS01505	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EH233_RS01510	COG0316	Belongs to the HesB IscA family
EH233_RS01515	COG0633	Ferredoxin
EH233_RS01520	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EH233_RS01550	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
EH233_RS01565	COG3706	GGDEF domain
EH233_RS01565	COG4251	negative regulation of phosphorylation
EH233_RS01565	COG5001	Diguanylate cyclase
EH233_RS01565	COG2203	Gaf domain
EH233_RS01570	COG0003	Pfam Anion-transporting ATPase
EH233_RS01610	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EH233_RS01630	COG0121	glutamine amidotransferase
EH233_RS01635	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EH233_RS01640	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
EH233_RS01655	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EH233_RS01685	COG1619	proteins homologs of microcin C7 resistance protein MccF
EH233_RS01690	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
EH233_RS01695	COG0415	Belongs to the DNA photolyase family
EH233_RS01700	COG2204	response regulator
EH233_RS01710	COG0322	excinuclease ABC activity
EH233_RS01725	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EH233_RS01735	COG1845	cytochrome c oxidase, subunit III
EH233_RS01750	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EH233_RS01765	COG4191	Histidine kinase
EH233_RS01775	COG1357	PFAM Pentapeptide repeats (8 copies)
EH233_RS01780	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EH233_RS01790	COG0612	Peptidase, M16
EH233_RS01795	COG0612	Peptidase, M16
EH233_RS01805	COG1950	PFAM Membrane protein of
EH233_RS01835	COG0702	epimerase
EH233_RS01845	COG0596	Alpha beta hydrolase
EH233_RS01855	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EH233_RS01860	COG1937	Protein conserved in bacteria
EH233_RS01865	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EH233_RS01875	COG4191	Histidine kinase
EH233_RS01880	COG5002	protein histidine kinase activity
EH233_RS01905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EH233_RS01910	COG0697	spore germination
EH233_RS01930	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EH233_RS01935	COG4106	trans-aconitate 2-methyltransferase activity
EH233_RS01940	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EH233_RS01955	COG3237	CsbD-like
EH233_RS01965	COG0556	nucleotide-excision repair
EH233_RS02005	COG1196	nuclear chromosome segregation
EH233_RS02015	COG1252	NADH dehydrogenase
EH233_RS02020	COG1252	NADH dehydrogenase
EH233_RS02030	COG0625	glutathione transferase activity
EH233_RS02035	COG3631	Ketosteroid isomerase-related protein
EH233_RS02040	COG0589	response to stress
EH233_RS02045	COG0784	Response regulator, receiver
EH233_RS02045	COG2205	protein histidine kinase activity
EH233_RS02060	COG0438	transferase activity, transferring glycosyl groups
EH233_RS02070	COG5002	protein histidine kinase activity
EH233_RS02070	COG0784	Response regulator, receiver
EH233_RS02095	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
EH233_RS02105	COG2267	carboxylic ester hydrolase activity
EH233_RS02110	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
EH233_RS02115	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
EH233_RS02125	COG4208	sulfate ABC transporter
EH233_RS02130	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EH233_RS02135	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EH233_RS02140	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EH233_RS02165	COG0121	glutamine amidotransferase
EH233_RS02170	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EH233_RS02180	COG5002	protein histidine kinase activity
EH233_RS02200	COG0584	glycerophosphoryl diester phosphodiesterase
EH233_RS02235	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EH233_RS02260	COG2207	Transcriptional regulator
EH233_RS02265	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EH233_RS02265	COG0300	oxidoreductase activity
EH233_RS02265	COG3321	synthase
EH233_RS02265	COG4221	oxidoreductase activity
EH233_RS02275	COG3321	synthase
EH233_RS02275	COG0604	alcohol dehydrogenase
EH233_RS02285	COG0604	alcohol dehydrogenase
EH233_RS02285	COG3321	synthase
EH233_RS02305	COG2070	2-Nitropropane dioxygenase
EH233_RS02305	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EH233_RS02320	COG0314	molybdopterin synthase activity
EH233_RS02345	COG0778	Nitroreductase
EH233_RS02350	COG1902	pentaerythritol trinitrate reductase activity
EH233_RS02355	COG3118	belongs to the thioredoxin family
EH233_RS02360	COG0640	Transcriptional regulator
EH233_RS02370	COG0515	serine threonine protein kinase
EH233_RS02370	COG1357	PFAM Pentapeptide repeats (8 copies)
EH233_RS02410	COG2217	Heavy metal translocating P-type atpase
EH233_RS02420	COG0288	reversible hydration of carbon dioxide
EH233_RS02425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EH233_RS02440	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EH233_RS02445	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EH233_RS02450	COG0484	heat shock protein binding
EH233_RS02455	COG0483	inositol monophosphate 1-phosphatase activity
EH233_RS02465	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EH233_RS02475	COG1028	Short-chain dehydrogenase reductase Sdr
EH233_RS02495	COG1040	competence protein
EH233_RS02505	COG0724	RNA recognition motif
EH233_RS02510	COG3338	carbonate dehydratase activity
EH233_RS02540	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
EH233_RS02545	COG2066	Belongs to the glutaminase family
EH233_RS02550	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EH233_RS02555	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
EH233_RS02555	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EH233_RS02560	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EH233_RS02570	COG0613	PHP domain protein
EH233_RS02585	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EH233_RS02590	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EH233_RS02590	COG0284	orotidine-5'-phosphate decarboxylase activity
EH233_RS02595	COG0628	permease
EH233_RS02620	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EH233_RS02625	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EH233_RS02630	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EH233_RS02640	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EH233_RS02640	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EH233_RS02660	COG0300	oxidoreductase activity
EH233_RS02685	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EH233_RS02695	COG1053	succinate dehydrogenase
EH233_RS02710	COG0837	glucose binding
EH233_RS02720	COG0681	Belongs to the peptidase S26 family
EH233_RS02750	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EH233_RS02755	COG0284	orotidine-5'-phosphate decarboxylase activity
EH233_RS02765	COG3781	membrane
EH233_RS02775	COG2234	aminopeptidase activity
EH233_RS02780	COG0443	Heat shock 70 kDa protein
EH233_RS02785	COG0484	heat shock protein binding
EH233_RS02795	COG0484	heat shock protein binding
EH233_RS02805	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EH233_RS02810	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
EH233_RS02815	COG0019	diaminopimelate decarboxylase activity
EH233_RS02820	COG0456	acetyltransferase
EH233_RS02825	COG0542	response to heat
EH233_RS02875	COG0390	transport system, permease component
EH233_RS02910	COG1573	uracil-dna glycosylase
EH233_RS02920	COG0668	transmembrane transport
EH233_RS02955	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
EH233_RS02980	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EH233_RS02990	COG1116	anion transmembrane transporter activity
EH233_RS02995	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EH233_RS02995	COG1116	anion transmembrane transporter activity
EH233_RS03000	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EH233_RS03005	COG3437	response regulator, receiver
EH233_RS03005	COG3850	Histidine kinase
EH233_RS03005	COG2205	protein histidine kinase activity
EH233_RS03005	COG4999	Histidine kinase
EH233_RS03015	COG1233	COG1233 Phytoene dehydrogenase and related
EH233_RS03025	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EH233_RS03030	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EH233_RS03035	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EH233_RS03060	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EH233_RS03085	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EH233_RS03090	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EH233_RS03105	COG2363	Small membrane protein
EH233_RS03110	COG4451	ribulose bisphosphate carboxylase, small
EH233_RS03110	COG0464	growth
EH233_RS03125	COG4451	ribulose bisphosphate carboxylase, small
EH233_RS03135	COG1850	ribulose-bisphosphate carboxylase activity
EH233_RS03145	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EH233_RS03155	COG0531	amino acid
EH233_RS03170	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EH233_RS03185	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
EH233_RS03190	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
EH233_RS03215	COG2124	cytochrome p450
EH233_RS03225	COG4782	Protein conserved in bacteria
EH233_RS03235	COG4636	protein conserved in cyanobacteria
EH233_RS03250	COG0582	viral genome integration into host DNA
EH233_RS03255	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
EH233_RS03265	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
EH233_RS03270	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
EH233_RS03285	COG5420	small protein containing a coiled-coil domain
EH233_RS03295	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EH233_RS03300	COG0316	Belongs to the HesB IscA family
EH233_RS03305	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EH233_RS03370	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EH233_RS03375	COG1045	serine acetyltransferase
EH233_RS03390	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EH233_RS03395	COG5554	nitrogen fixation
EH233_RS03400	COG5554	nitrogen fixation
EH233_RS03425	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EH233_RS03440	COG0066	3-isopropylmalate dehydratase activity
EH233_RS03445	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EH233_RS03450	COG0300	oxidoreductase activity
EH233_RS03455	COG2264	protein methyltransferase activity
EH233_RS03490	COG2198	Histidine kinase
EH233_RS03490	COG0784	Response regulator, receiver
EH233_RS03490	COG5002	protein histidine kinase activity
EH233_RS03515	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EH233_RS03550	COG0318	PFAM AMP-dependent synthetase and ligase
EH233_RS03555	COG2986	histidine ammonia-lyase
EH233_RS03600	COG0515	serine threonine protein kinase
EH233_RS03600	COG2815	serine threonine protein kinase
EH233_RS03605	COG0737	Belongs to the 5'-nucleotidase family
EH233_RS03685	COG4935	Belongs to the peptidase S8 family
EH233_RS03685	COG1404	Belongs to the peptidase S8 family
EH233_RS03710	COG1940	carbohydrate kinase activity
EH233_RS03720	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EH233_RS03725	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EH233_RS03730	COG0742	ribosomal rna small subunit methyltransferase
EH233_RS03740	COG2010	Cytochrome c
EH233_RS03745	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EH233_RS03755	COG0515	serine threonine protein kinase
EH233_RS03755	COG2815	serine threonine protein kinase
EH233_RS03775	COG0589	response to stress
EH233_RS03785	COG0339	signal peptide processing
EH233_RS03800	COG1254	Belongs to the acylphosphatase family
EH233_RS03815	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
EH233_RS03835	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EH233_RS03840	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EH233_RS03845	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
EH233_RS03850	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
EH233_RS03855	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
EH233_RS03865	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EH233_RS03865	COG4451	ribulose bisphosphate carboxylase, small
EH233_RS03875	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EH233_RS03880	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
EH233_RS03885	COG0583	DNA-binding transcription factor activity
EH233_RS03895	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EH233_RS03900	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EH233_RS03930	COG2202	Pas domain
EH233_RS03930	COG2205	protein histidine kinase activity
EH233_RS03945	COG2267	carboxylic ester hydrolase activity
EH233_RS03975	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EH233_RS03980	COG0193	aminoacyl-tRNA hydrolase activity
EH233_RS03985	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EH233_RS04005	COG0123	including yeast histone deacetylase and acetoin utilization protein
EH233_RS04020	COG3659	wide pore channel activity
EH233_RS04025	COG0803	Belongs to the bacterial solute-binding protein 9 family
EH233_RS04030	COG1121	(ABC) transporter
EH233_RS04035	COG0640	Transcriptional regulator
EH233_RS04040	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EH233_RS04060	COG1902	pentaerythritol trinitrate reductase activity
EH233_RS04080	COG0745	RESPONSE REGULATOR receiver
EH233_RS04095	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EH233_RS04095	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EH233_RS04100	COG2130	NADP-dependent
EH233_RS04105	COG2831	hemolysin activation secretion protein
EH233_RS04115	COG1773	rubredoxin
EH233_RS04120	COG0783	Belongs to the Dps family
EH233_RS04125	COG1741	Belongs to the pirin family
EH233_RS04160	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EH233_RS04165	COG2267	carboxylic ester hydrolase activity
EH233_RS04175	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EH233_RS04190	COG0505	Belongs to the CarA family
EH233_RS04200	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EH233_RS04275	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EH233_RS04295	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
EH233_RS04310	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EH233_RS04315	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EH233_RS04330	COG0571	ribonuclease III activity
EH233_RS04345	COG0598	Magnesium transport protein CorA
EH233_RS04350	COG0751	glycine-tRNA ligase activity
EH233_RS04355	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EH233_RS04360	COG5002	protein histidine kinase activity
EH233_RS04365	COG0745	RESPONSE REGULATOR receiver
EH233_RS04385	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
EH233_RS04400	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EH233_RS04405	COG0460	homoserine dehydrogenase
EH233_RS04410	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EH233_RS04415	COG0572	uridine kinase
EH233_RS04420	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EH233_RS04445	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
EH233_RS04455	COG1051	belongs to the nudix hydrolase family
EH233_RS04460	COG0126	phosphoglycerate kinase activity
EH233_RS04465	COG0589	response to stress
EH233_RS04505	COG1217	gtp-binding protein TYPA
EH233_RS04530	COG0783	Belongs to the Dps family
EH233_RS04540	COG2385	sporulation resulting in formation of a cellular spore
EH233_RS04545	COG0633	Ferredoxin
EH233_RS04550	COG0673	inositol 2-dehydrogenase activity
EH233_RS04555	COG0024	Methionine aminopeptidase
EH233_RS04570	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
EH233_RS04575	COG4279	zinc finger
EH233_RS04580	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EH233_RS04585	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EH233_RS04605	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EH233_RS04610	COG0602	queuosine metabolic process
EH233_RS04630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EH233_RS04635	COG4597	amino acid ABC transporter
EH233_RS04640	COG0765	amino acid transport
EH233_RS04645	COG1126	abc transporter atp-binding protein
EH233_RS04650	COG0297	glycogen (starch) synthase activity
EH233_RS04655	COG0799	negative regulation of ribosome biogenesis
EH233_RS04685	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EH233_RS04690	COG1381	Involved in DNA repair and RecF pathway recombination
EH233_RS04700	COG0438	transferase activity, transferring glycosyl groups
EH233_RS04720	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EH233_RS04725	COG0488	(ABC) transporter
EH233_RS04740	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EH233_RS04745	COG0254	rRNA binding
EH233_RS04750	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EH233_RS04755	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EH233_RS04760	COG0101	tRNA pseudouridine synthase activity
EH233_RS04765	COG0203	ribosomal protein L17
EH233_RS04770	COG0202	RNA polymerase activity
EH233_RS04775	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EH233_RS04780	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EH233_RS04785	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EH233_RS04790	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EH233_RS04795	COG0563	adenylate kinase activity
EH233_RS04800	COG0201	protein transport
EH233_RS04805	COG0200	Binds to the 23S rRNA
EH233_RS04810	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EH233_RS04815	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EH233_RS04820	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EH233_RS04825	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EH233_RS04830	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EH233_RS04835	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EH233_RS04840	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EH233_RS04845	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EH233_RS04850	COG0255	Belongs to the universal ribosomal protein uL29 family
EH233_RS04855	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EH233_RS04860	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EH233_RS04865	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EH233_RS04870	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EH233_RS04880	COG0088	Forms part of the polypeptide exit tunnel
EH233_RS04885	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EH233_RS04915	COG0596	Alpha beta hydrolase
EH233_RS04920	COG3021	interspecies interaction between organisms
EH233_RS04935	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EH233_RS04940	COG0667	Aldo Keto reductase
EH233_RS04960	COG3228	Belongs to the MtfA family
EH233_RS04965	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EH233_RS04980	COG0464	growth
EH233_RS04985	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EH233_RS05000	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
EH233_RS05005	COG2119	membrane
EH233_RS05020	COG4636	protein conserved in cyanobacteria
EH233_RS05050	COG0745	RESPONSE REGULATOR receiver
EH233_RS05075	COG1131	(ABC) transporter
EH233_RS05100	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EH233_RS05100	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EH233_RS05120	COG1077	Cell shape determining protein MreB Mrl
EH233_RS05125	COG0629	single-stranded DNA binding
EH233_RS05135	COG0475	glutathione-regulated potassium exporter activity
EH233_RS05140	COG0860	N-Acetylmuramoyl-L-alanine amidase
EH233_RS05140	COG2247	cell wall binding repeat
EH233_RS05150	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EH233_RS05160	COG0142	geranyltranstransferase activity
EH233_RS05185	COG1305	Transglutaminase-like
EH233_RS05195	COG2052	Domain of unknown function (DUF370)
EH233_RS05205	COG0194	GDP metabolic process
EH233_RS05225	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EH233_RS05240	COG0454	-acetyltransferase
EH233_RS05255	COG2890	protein-(glutamine-N5) methyltransferase activity
EH233_RS05270	COG0454	-acetyltransferase
EH233_RS05280	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EH233_RS05285	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EH233_RS05290	COG0022	dehydrogenase e1 component
EH233_RS05290	COG0508	dehydrogenase complex catalyzes the overall conversion of
EH233_RS05310	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EH233_RS05320	COG0644	oxidoreductase
EH233_RS05325	COG0745	RESPONSE REGULATOR receiver
EH233_RS05330	COG0429	hydrolase of the alpha beta-hydrolase fold
EH233_RS05360	COG0539	negative regulation of cytoplasmic translation
EH233_RS05385	COG0747	negative chemotaxis
EH233_RS05390	COG0601	transmembrane transport
EH233_RS05395	COG0328	RNA-DNA hybrid ribonuclease activity
EH233_RS05415	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EH233_RS05420	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EH233_RS05435	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
EH233_RS05440	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EH233_RS05445	COG0772	Belongs to the SEDS family
EH233_RS05475	COG0438	transferase activity, transferring glycosyl groups
EH233_RS05485	COG2010	Cytochrome c
EH233_RS05500	COG1950	PFAM Membrane protein of
EH233_RS05510	COG2183	response to ionizing radiation
EH233_RS05520	COG1192	Involved in chromosome partitioning
EH233_RS05560	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EH233_RS05585	COG2217	Heavy metal translocating P-type atpase
EH233_RS05605	COG0515	serine threonine protein kinase
EH233_RS05605	COG1357	PFAM Pentapeptide repeats (8 copies)
EH233_RS05625	COG4249	Peptidase C14 caspase catalytic subunit p20
EH233_RS05625	COG2319	Wd-40 repeat
EH233_RS05665	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EH233_RS05670	COG1505	serine-type exopeptidase activity
EH233_RS05675	COG1175	transmembrane transport
EH233_RS05695	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EH233_RS05720	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EH233_RS05755	COG4231	catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates
EH233_RS05775	COG3848	Pyruvate phosphate dikinase
EH233_RS05775	COG0574	Belongs to the PEP-utilizing enzyme family
EH233_RS05780	COG0481	GTPase activity
EH233_RS05795	COG1104	cysteine desulfurase activity
EH233_RS05805	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EH233_RS05810	COG2815	serine threonine protein kinase
EH233_RS05810	COG0515	serine threonine protein kinase
EH233_RS05815	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EH233_RS05820	COG0793	Belongs to the peptidase S41A family
EH233_RS05830	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EH233_RS05835	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EH233_RS05845	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EH233_RS05850	COG0719	Fe-S assembly protein
EH233_RS05855	COG0396	ATPase activity
EH233_RS05860	COG0719	Fe-S assembly protein
EH233_RS05880	COG0393	Putative heavy-metal-binding
EH233_RS05890	COG1131	(ABC) transporter
EH233_RS05895	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EH233_RS05895	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EH233_RS05905	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EH233_RS05930	COG1316	TRANSCRIPTIONal
EH233_RS05940	COG0628	permease
EH233_RS05950	COG0047	phosphoribosylformylglycinamidine synthase activity
EH233_RS05955	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EH233_RS05965	COG0330	HflC and HflK could
EH233_RS06000	COG0824	Thioesterase
EH233_RS06040	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EH233_RS06055	COG0805	protein transport
EH233_RS06065	COG0723	plastoquinol--plastocyanin reductase activity
EH233_RS06070	COG0739	heme binding
EH233_RS06080	COG1543	Belongs to the glycosyl hydrolase 57 family
EH233_RS06085	COG1162	GTPase activity
EH233_RS06095	COG0484	heat shock protein binding
EH233_RS06100	COG0443	Heat shock 70 kDa protein
EH233_RS06105	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EH233_RS06110	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EH233_RS06120	COG1459	type II secretion system
EH233_RS06130	COG1748	Saccharopine dehydrogenase
EH233_RS06140	COG4636	protein conserved in cyanobacteria
EH233_RS06150	COG3932	Exopolysaccharide synthesis, ExoD
EH233_RS06155	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EH233_RS06155	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
EH233_RS06205	COG0438	transferase activity, transferring glycosyl groups
EH233_RS06210	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EH233_RS06250	COG2204	response regulator
EH233_RS06265	COG0315	cyclic pyranopterin monophosphate synthase activity
EH233_RS06275	COG2814	Major facilitator Superfamily
EH233_RS06280	COG0463	Glycosyl transferase, family 2
EH233_RS06300	COG1305	Transglutaminase-like
EH233_RS06305	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EH233_RS06310	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EH233_RS06320	COG1285	pathogenesis
EH233_RS06325	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EH233_RS06325	COG0574	Belongs to the PEP-utilizing enzyme family
EH233_RS06335	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EH233_RS06345	COG0515	serine threonine protein kinase
EH233_RS06355	COG0631	protein serine/threonine phosphatase activity
EH233_RS06360	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EH233_RS06365	COG3937	granule-associated protein
EH233_RS06375	COG0446	pyridine nucleotide-disulphide oxidoreductase
EH233_RS06380	COG0723	plastoquinol--plastocyanin reductase activity
EH233_RS06405	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EH233_RS06420	COG0745	RESPONSE REGULATOR receiver
EH233_RS06425	COG5002	protein histidine kinase activity
EH233_RS06430	COG0704	Plays a role in the regulation of phosphate uptake
EH233_RS06435	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EH233_RS06440	COG3659	wide pore channel activity
EH233_RS06455	COG2205	protein histidine kinase activity
EH233_RS06455	COG0784	Response regulator, receiver
EH233_RS06465	COG0438	transferase activity, transferring glycosyl groups
EH233_RS06470	COG4106	trans-aconitate 2-methyltransferase activity
EH233_RS06490	COG1091	dTDP-4-dehydrorhamnose reductase activity
EH233_RS06505	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EH233_RS06510	COG0463	Glycosyl transferase, family 2
EH233_RS06555	COG0003	Pfam Anion-transporting ATPase
EH233_RS06560	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EH233_RS06565	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EH233_RS06600	COG0483	inositol monophosphate 1-phosphatase activity
EH233_RS06615	COG0175	sulfate reduction
EH233_RS06630	COG1247	-acetyltransferase
EH233_RS06655	COG1598	PFAM Uncharacterised protein family UPF0150
EH233_RS06730	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EH233_RS06740	COG5002	protein histidine kinase activity
EH233_RS06745	COG0745	RESPONSE REGULATOR receiver
EH233_RS06750	COG3706	GGDEF domain
EH233_RS06750	COG5001	Diguanylate cyclase
EH233_RS06750	COG2203	Gaf domain
EH233_RS06750	COG4251	negative regulation of phosphorylation
EH233_RS06760	COG0643	Histidine kinase
EH233_RS06760	COG0784	Response regulator, receiver
EH233_RS06760	COG2198	Histidine kinase
EH233_RS06765	COG0840	transmembrane signaling receptor activity
EH233_RS06780	COG0784	Response regulator, receiver
EH233_RS06785	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EH233_RS06790	COG0860	N-Acetylmuramoyl-L-alanine amidase
EH233_RS06790	COG3409	Peptidoglycan-binding domain 1 protein
EH233_RS06830	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EH233_RS06835	COG0581	inorganic phosphate transmembrane transporter activity
EH233_RS06840	COG0573	inorganic phosphate transmembrane transporter activity
EH233_RS06845	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EH233_RS06850	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EH233_RS06875	COG2319	Wd-40 repeat
EH233_RS06875	COG4249	Peptidase C14 caspase catalytic subunit p20
EH233_RS06890	COG0723	plastoquinol--plastocyanin reductase activity
EH233_RS06900	COG1480	7TM receptor with intracellular HD hydrolase
EH233_RS06910	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EH233_RS06915	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EH233_RS06915	COG1754	DNA topoisomerase type I activity
EH233_RS06930	COG0724	RNA recognition motif
EH233_RS06935	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EH233_RS06950	COG2205	protein histidine kinase activity
EH233_RS06955	COG0129	dihydroxy-acid dehydratase activity
EH233_RS06960	COG0463	Glycosyl transferase, family 2
EH233_RS06965	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EH233_RS06965	COG0352	thiamine-phosphate diphosphorylase activity
EH233_RS06965	COG0351	phosphomethylpyrimidine kinase
EH233_RS06980	COG0640	Transcriptional regulator
EH233_RS06985	COG0436	Aminotransferase
EH233_RS06990	COG0371	Dehydrogenase
EH233_RS07005	COG2267	carboxylic ester hydrolase activity
EH233_RS07050	COG0601	transmembrane transport
EH233_RS07055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EH233_RS07060	COG0592	DNA-directed DNA polymerase activity
EH233_RS07065	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EH233_RS07070	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EH233_RS07075	COG1575	Belongs to the MenA family. Type 1 subfamily
EH233_RS07080	COG1169	isochorismate synthase
EH233_RS07085	COG0297	glycogen (starch) synthase activity
EH233_RS07095	COG3903	Transcriptional regulator
EH233_RS07095	COG2319	Wd-40 repeat
EH233_RS07120	COG2912	Transglutaminase-like superfamily
EH233_RS07140	COG0237	dephospho-CoA kinase activity
EH233_RS07140	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EH233_RS07150	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EH233_RS07160	COG0356	it plays a direct role in the translocation of protons across the membrane
EH233_RS07165	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EH233_RS07170	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EH233_RS07175	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EH233_RS07180	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EH233_RS07185	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EH233_RS07190	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EH233_RS07220	COG2226	methyltransferase
EH233_RS07230	COG1079	Belongs to the binding-protein-dependent transport system permease family
EH233_RS07235	COG4603	Belongs to the binding-protein-dependent transport system permease family
EH233_RS07250	COG3845	ABC transporter
EH233_RS07260	COG2091	lysine biosynthetic process via aminoadipic acid
EH233_RS07265	COG0300	oxidoreductase activity
EH233_RS07275	COG3320	Male sterility
EH233_RS07275	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EH233_RS07280	COG2070	2-Nitropropane dioxygenase
EH233_RS07280	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EH233_RS07285	COG0300	oxidoreductase activity
EH233_RS07285	COG4221	oxidoreductase activity
EH233_RS07285	COG3321	synthase
EH233_RS07285	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EH233_RS07295	COG3321	synthase
EH233_RS07295	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EH233_RS07295	COG1028	Short-chain dehydrogenase reductase Sdr
EH233_RS07295	COG4221	oxidoreductase activity
EH233_RS07300	COG3321	synthase
EH233_RS07300	COG0604	alcohol dehydrogenase
EH233_RS07315	COG1475	DNA binding
EH233_RS07365	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EH233_RS07440	COG2885	chlorophyll binding
EH233_RS07460	COG2205	protein histidine kinase activity
EH233_RS07460	COG0784	Response regulator, receiver
EH233_RS07475	COG0438	transferase activity, transferring glycosyl groups
EH233_RS07490	COG0426	domain, Protein
EH233_RS07490	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EH233_RS07500	COG0426	domain, Protein
EH233_RS07500	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EH233_RS07510	COG0165	Argininosuccinate lyase
EH233_RS07520	COG1691	(AIR) carboxylase
EH233_RS07525	COG0747	negative chemotaxis
EH233_RS07530	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EH233_RS07535	COG0336	Belongs to the RNA methyltransferase TrmD family
EH233_RS07540	COG4242	Belongs to the peptidase S51 family
EH233_RS07545	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EH233_RS07545	COG0189	ligase activity
EH233_RS07550	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EH233_RS07555	COG3266	domain, Protein
EH233_RS07555	COG0515	serine threonine protein kinase
EH233_RS07565	COG0575	Belongs to the CDS family
EH233_RS07575	COG1187	pseudouridine synthase activity
EH233_RS07580	COG1426	Protein conserved in bacteria
EH233_RS07585	COG1640	4-alpha-glucanotransferase
EH233_RS07595	COG0251	oxidation-reduction process
EH233_RS07605	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EH233_RS07625	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EH233_RS07645	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EH233_RS07650	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EH233_RS07655	COG0189	ligase activity
EH233_RS07660	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EH233_RS07680	COG4249	Peptidase C14 caspase catalytic subunit p20
EH233_RS07680	COG2319	Wd-40 repeat
EH233_RS07695	COG1191	sigma factor activity
EH233_RS07760	COG4447	cellulose binding
EH233_RS07765	COG1773	rubredoxin
EH233_RS07770	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EH233_RS07775	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EH233_RS07780	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EH233_RS07815	COG3266	domain, Protein
EH233_RS07815	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EH233_RS07825	COG0195	Participates in both transcription termination and antitermination
EH233_RS07830	COG0779	Required for maturation of 30S ribosomal subunits
EH233_RS07860	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
EH233_RS07865	COG0745	RESPONSE REGULATOR receiver
EH233_RS07925	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EH233_RS07935	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EH233_RS07940	COG0052	Belongs to the universal ribosomal protein uS2 family
EH233_RS07955	COG1216	Glycosyl transferase, family 2
EH233_RS07975	COG0137	argininosuccinate synthase activity
EH233_RS07980	COG0586	Pfam SNARE associated Golgi protein
EH233_RS07995	COG0360	Binds together with S18 to 16S ribosomal RNA
EH233_RS08000	COG0179	Fumarylacetoacetate (FAA) hydrolase
EH233_RS08015	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EH233_RS08020	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EH233_RS08025	COG1058	Belongs to the CinA family
EH233_RS08025	COG1546	Belongs to the CinA family
EH233_RS08030	COG4636	protein conserved in cyanobacteria
EH233_RS08045	COG0159	tryptophan synthase activity
EH233_RS08055	COG0515	serine threonine protein kinase
EH233_RS08055	COG3266	domain, Protein
EH233_RS08075	COG4115	mRNA cleavage
EH233_RS08085	COG0038	chloride channel
EH233_RS08105	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EH233_RS08110	COG0395	ABC-type sugar transport system, permease component
EH233_RS08115	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EH233_RS08120	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EH233_RS08125	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
EH233_RS08130	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EH233_RS08135	COG0438	transferase activity, transferring glycosyl groups
EH233_RS08150	COG2124	cytochrome p450
EH233_RS08155	COG4249	Peptidase C14 caspase catalytic subunit p20
EH233_RS08155	COG2319	Wd-40 repeat
EH233_RS08180	COG1357	PFAM Pentapeptide repeats (8 copies)
EH233_RS08180	COG0515	serine threonine protein kinase
EH233_RS08190	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EH233_RS08195	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EH233_RS08200	COG0514	ATP-dependent DNA helicase (RecQ)
EH233_RS08205	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EH233_RS08210	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EH233_RS08215	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EH233_RS08220	COG1234	tRNA 3'-trailer cleavage
EH233_RS08225	COG0196	riboflavin kinase activity
EH233_RS08230	COG0714	Associated with various cellular activities
EH233_RS08250	COG0653	protein targeting
EH233_RS08255	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EH233_RS08265	COG0436	Aminotransferase
EH233_RS08280	COG4680	protein conserved in bacteria
EH233_RS08285	COG0457	Tetratricopeptide repeat
EH233_RS08285	COG0463	Glycosyl transferase, family 2
EH233_RS08300	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
EH233_RS08315	COG1696	Membrane protein involved in D-alanine export
EH233_RS08350	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EH233_RS08355	COG4178	(ABC) transporter
EH233_RS08375	COG3621	Patatin-like phospholipase
EH233_RS08385	COG4178	(ABC) transporter
EH233_RS08395	COG2319	Wd-40 repeat
EH233_RS08395	COG1672	PFAM Archaeal ATPase
EH233_RS08410	COG3437	response regulator, receiver
EH233_RS08415	COG2205	protein histidine kinase activity
EH233_RS08415	COG2202	Pas domain
EH233_RS08435	COG0668	transmembrane transport
EH233_RS08440	COG0475	glutathione-regulated potassium exporter activity
EH233_RS08485	COG4802	Ferredoxin thioredoxin reductase catalytic beta chain
EH233_RS08495	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EH233_RS08510	COG1696	Membrane protein involved in D-alanine export
EH233_RS08515	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EH233_RS08515	COG3321	synthase
EH233_RS08515	COG0300	oxidoreductase activity
EH233_RS08515	COG4221	oxidoreductase activity
EH233_RS08520	COG1960	acyl-CoA dehydrogenase activity
EH233_RS08525	COG0318	PFAM AMP-dependent synthetase and ligase
EH233_RS08535	COG0354	folic acid binding
EH233_RS08545	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EH233_RS08555	COG3959	Transketolase, thiamine diphosphate binding domain
EH233_RS08575	COG0435	Glutathione S-transferase
EH233_RS08585	COG1420	regulation of RNA biosynthetic process
EH233_RS08615	COG1045	serine acetyltransferase
EH233_RS08620	COG0259	pyridoxamine-phosphate oxidase activity
EH233_RS08665	COG0724	RNA recognition motif
EH233_RS08670	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EH233_RS08675	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EH233_RS08680	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EH233_RS08685	COG3409	Peptidoglycan-binding domain 1 protein
EH233_RS08685	COG3429	Glucose-6-phosphate dehydrogenase subunit
EH233_RS08705	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EH233_RS08715	COG0616	signal peptide processing
EH233_RS08725	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
EH233_RS08740	COG0469	pyruvate kinase activity
EH233_RS08770	COG0515	serine threonine protein kinase
EH233_RS08770	COG3266	domain, Protein
EH233_RS08780	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EH233_RS08800	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EH233_RS08825	COG3609	addiction module antidote protein, CC2985 family
EH233_RS08830	COG0617	tRNA 3'-terminal CCA addition
EH233_RS08830	COG0517	IMP dehydrogenase activity
EH233_RS08830	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EH233_RS08835	COG0419	ATPase involved in DNA repair
EH233_RS08840	COG2205	protein histidine kinase activity
EH233_RS08840	COG0784	Response regulator, receiver
EH233_RS08850	COG1361	Conserved repeat domain
EH233_RS08855	COG5002	protein histidine kinase activity
EH233_RS08880	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EH233_RS08910	COG0750	zinc metalloprotease
EH233_RS08915	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EH233_RS08920	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EH233_RS08930	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
EH233_RS08945	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EH233_RS08980	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EH233_RS08985	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EH233_RS08990	COG3118	belongs to the thioredoxin family
EH233_RS09000	COG0583	DNA-binding transcription factor activity
EH233_RS09005	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EH233_RS09010	COG0018	arginyl-trna synthetase
EH233_RS09015	COG0561	phosphatase activity
EH233_RS09020	COG1122	ATPase activity
EH233_RS09030	COG0310	cobalt ion transport
EH233_RS09035	COG1122	ATPase activity
EH233_RS09045	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
EH233_RS09050	COG0310	cobalt ion transport
EH233_RS09055	COG2132	Multicopper oxidase
EH233_RS09070	COG0672	)-iron permease
EH233_RS09075	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EH233_RS09085	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EH233_RS09090	COG0776	regulation of translation
EH233_RS09215	COG0716	FMN binding
EH233_RS09225	COG0745	RESPONSE REGULATOR receiver
EH233_RS09250	COG2205	protein histidine kinase activity
EH233_RS09270	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
EH233_RS09290	COG1902	pentaerythritol trinitrate reductase activity
EH233_RS09305	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EH233_RS09310	COG0459	protein refolding
EH233_RS09325	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EH233_RS09325	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EH233_RS09330	COG0443	Heat shock 70 kDa protein
EH233_RS09335	COG4572	Cation transport regulator
EH233_RS09345	COG0656	L-ascorbic acid biosynthetic process
EH233_RS09360	COG0484	heat shock protein binding
EH233_RS09370	COG0542	response to heat
EH233_RS09390	COG2080	2 iron, 2 sulfur cluster binding
EH233_RS09395	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
EH233_RS09400	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EH233_RS09405	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EH233_RS09410	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EH233_RS09415	COG1475	DNA binding
EH233_RS09425	COG1192	Involved in chromosome partitioning
EH233_RS09445	COG0515	serine threonine protein kinase
EH233_RS09445	COG2815	serine threonine protein kinase
EH233_RS09450	COG2197	response regulator
EH233_RS09455	COG2207	Transcriptional regulator
EH233_RS09470	COG4221	oxidoreductase activity
EH233_RS09475	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EH233_RS09475	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EH233_RS09490	COG1028	Short-chain dehydrogenase reductase Sdr
EH233_RS09505	COG0604	alcohol dehydrogenase
EH233_RS09505	COG1028	Short-chain dehydrogenase reductase Sdr
EH233_RS09505	COG3321	synthase
EH233_RS09515	COG2267	carboxylic ester hydrolase activity
EH233_RS09545	COG1429	ligase activity, forming nitrogen-metal bonds
EH233_RS09550	COG1132	(ABC) transporter
EH233_RS09555	COG1132	(ABC) transporter
EH233_RS09565	COG0745	RESPONSE REGULATOR receiver
EH233_RS09570	COG5000	phosphorelay sensor kinase activity
EH233_RS09570	COG5002	protein histidine kinase activity
EH233_RS09575	COG0113	porphobilinogen synthase activity
EH233_RS09580	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EH233_RS09585	COG0523	cobalamin synthesis protein
EH233_RS09590	COG0302	gtp cyclohydrolase
EH233_RS09600	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EH233_RS09605	COG0513	Belongs to the DEAD box helicase family
EH233_RS09615	COG5002	protein histidine kinase activity
EH233_RS09620	COG1132	(ABC) transporter
EH233_RS09630	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EH233_RS09645	COG2234	aminopeptidase activity
EH233_RS09655	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EH233_RS09680	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EH233_RS09685	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EH233_RS09710	COG2954	triphosphatase activity
EH233_RS09725	COG1846	Transcriptional regulator
EH233_RS09735	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EH233_RS09755	COG2124	cytochrome p450
EH233_RS09760	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EH233_RS09770	COG0724	RNA recognition motif
EH233_RS09775	COG1218	3'(2'),5'-bisphosphate nucleotidase
EH233_RS09785	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EH233_RS09795	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EH233_RS09810	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EH233_RS09825	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EH233_RS09830	COG3266	domain, Protein
EH233_RS09830	COG0515	serine threonine protein kinase
EH233_RS09835	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EH233_RS09845	COG0857	belongs to the CobB CobQ family
EH233_RS09860	COG1666	GTP binding
EH233_RS09865	COG0625	glutathione transferase activity
EH233_RS09890	COG1070	Carbohydrate kinase
EH233_RS09895	COG2971	BadF BadG BcrA BcrD
EH233_RS09910	COG3237	CsbD-like
EH233_RS09945	COG0800	Aldolase
EH233_RS09955	COG2066	Belongs to the glutaminase family
EH233_RS09965	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EH233_RS09980	COG0745	RESPONSE REGULATOR receiver
EH233_RS09985	COG5002	protein histidine kinase activity
EH233_RS09995	COG3659	wide pore channel activity
EH233_RS10005	COG1132	(ABC) transporter
EH233_RS10010	COG0438	transferase activity, transferring glycosyl groups
EH233_RS10025	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EH233_RS10030	COG2239	Acts as a magnesium transporter
EH233_RS10040	COG1028	Short-chain dehydrogenase reductase Sdr
EH233_RS10060	COG0725	ABC transporter, periplasmic molybdate-binding protein
EH233_RS10080	COG5002	protein histidine kinase activity
EH233_RS10085	COG0745	RESPONSE REGULATOR receiver
EH233_RS10110	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EH233_RS10125	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EH233_RS10155	COG2885	chlorophyll binding
EH233_RS10160	COG2885	chlorophyll binding
EH233_RS10170	COG1234	tRNA 3'-trailer cleavage
EH233_RS10195	COG2274	protein secretion by the type I secretion system
EH233_RS10230	COG2226	methyltransferase
EH233_RS10245	COG0463	Glycosyl transferase, family 2
EH233_RS10275	COG2046	Belongs to the sulfate adenylyltransferase family
EH233_RS10285	COG0303	'Molybdopterin
EH233_RS10295	COG2119	membrane
EH233_RS10350	COG1028	Short-chain dehydrogenase reductase Sdr
EH233_RS10360	COG1131	(ABC) transporter
EH233_RS10370	COG0517	IMP dehydrogenase activity
EH233_RS10370	COG1125	glycine betaine transport
EH233_RS10395	COG0004	ammonium transporteR
EH233_RS10400	COG0004	ammonium transporteR
EH233_RS10405	COG0004	ammonium transporteR
EH233_RS10410	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EH233_RS10415	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EH233_RS10430	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EH233_RS10450	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EH233_RS10455	COG2205	protein histidine kinase activity
EH233_RS10465	COG1012	belongs to the aldehyde dehydrogenase family
EH233_RS10475	COG2226	methyltransferase
EH233_RS10480	COG0237	dephospho-CoA kinase activity
EH233_RS10485	COG0237	dephospho-CoA kinase activity
EH233_RS10490	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EH233_RS10495	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EH233_RS10500	COG1413	lyase activity
EH233_RS10505	COG1413	lyase activity
EH233_RS10510	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EH233_RS10515	COG0237	dephospho-CoA kinase activity
EH233_RS10530	COG1413	lyase activity
EH233_RS10535	COG1413	lyase activity
EH233_RS10540	COG0237	dephospho-CoA kinase activity
EH233_RS10555	COG0564	pseudouridine synthase activity
EH233_RS10560	COG0784	Response regulator, receiver
EH233_RS10565	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EH233_RS10595	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
EH233_RS10600	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EH233_RS10610	COG3956	TIGRFAM MazG family protein
EH233_RS10645	COG0489	protein tyrosine kinase activity
EH233_RS10645	COG3206	protein involved in exopolysaccharide biosynthesis
EH233_RS10650	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EH233_RS10665	COG1216	Glycosyl transferase, family 2
EH233_RS10665	COG0463	Glycosyl transferase, family 2
EH233_RS10675	COG4581	dead DEAH box helicase
EH233_RS10680	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EH233_RS10685	COG1799	cell septum assembly
EH233_RS10690	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EH233_RS10700	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
EH233_RS10705	COG1160	GTP binding
EH233_RS10755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EH233_RS10775	COG2442	InterPro IPR007367
EH233_RS10785	COG4804	nuclease activity
EH233_RS10845	COG2831	hemolysin activation secretion protein
EH233_RS10935	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EH233_RS10950	COG0589	response to stress
EH233_RS10955	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EH233_RS10960	COG0268	Binds directly to 16S ribosomal RNA
EH233_RS10965	COG0084	hydrolase, TatD family'
EH233_RS10975	COG0085	RNA polymerase activity
EH233_RS10980	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EH233_RS10985	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EH233_RS10990	COG3239	Fatty acid desaturase
EH233_RS10995	COG3239	Fatty acid desaturase
EH233_RS11005	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
EH233_RS11010	COG1035	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
EH233_RS11015	COG0363	glucosamine-6-phosphate deaminase activity
EH233_RS11020	COG1716	ATPase activity
EH233_RS11030	COG2385	sporulation resulting in formation of a cellular spore
EH233_RS11060	COG1136	(ABC) transporter
EH233_RS11060	COG0577	efflux transmembrane transporter activity
EH233_RS11065	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EH233_RS11070	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EH233_RS11080	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EH233_RS11100	COG0017	Asparaginyl-tRNA synthetase
EH233_RS11110	COG0745	RESPONSE REGULATOR receiver
EH233_RS11115	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EH233_RS11120	COG0459	protein refolding
EH233_RS11140	COG1192	Involved in chromosome partitioning
EH233_RS11145	COG0829	nickel cation binding
EH233_RS11150	COG0831	urea catabolic process
EH233_RS11155	COG0832	Belongs to the urease beta subunit family
EH233_RS11165	COG0804	urea catabolic process
EH233_RS11180	COG1012	belongs to the aldehyde dehydrogenase family
EH233_RS11185	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EH233_RS11190	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EH233_RS11210	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EH233_RS11220	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
EH233_RS11225	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EH233_RS11230	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EH233_RS11240	COG0544	peptidyl-prolyl cis-trans isomerase activity
EH233_RS11245	COG0740	serine-type endopeptidase activity
EH233_RS11250	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EH233_RS11290	COG0668	transmembrane transport
EH233_RS11320	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EH233_RS11340	COG1136	(ABC) transporter
EH233_RS11370	COG1690	Belongs to the RtcB family
EH233_RS11375	COG2226	methyltransferase
EH233_RS11395	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EH233_RS11400	COG1166	arginine decarboxylase activity
EH233_RS11405	COG0105	UTP biosynthetic process
EH233_RS11410	COG0861	Integral membrane protein TerC family
EH233_RS11445	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EH233_RS11450	COG0594	ribonuclease P activity
EH233_RS11460	COG0706	membrane insertase activity
EH233_RS11490	COG0793	Belongs to the peptidase S41A family
EH233_RS11495	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EH233_RS11500	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EH233_RS11515	COG0438	transferase activity, transferring glycosyl groups
EH233_RS11525	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EH233_RS11530	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EH233_RS11535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EH233_RS11555	COG0745	RESPONSE REGULATOR receiver
EH233_RS11565	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EH233_RS11590	COG1028	Short-chain dehydrogenase reductase Sdr
EH233_RS11595	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EH233_RS11620	COG0322	excinuclease ABC activity
EH233_RS11625	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
EH233_RS11635	COG0512	Glutamine amidotransferase of anthranilate synthase
EH233_RS11635	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EH233_RS11655	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EH233_RS11665	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EH233_RS11680	COG0850	regulation of cytokinetic process
EH233_RS11685	COG2894	cell division
EH233_RS11690	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
EH233_RS11700	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EH233_RS11720	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EH233_RS11750	COG0860	N-Acetylmuramoyl-L-alanine amidase
EH233_RS11750	COG3409	Peptidoglycan-binding domain 1 protein
EH233_RS11760	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EH233_RS11795	COG2770	Histidine kinase
EH233_RS11795	COG3437	response regulator, receiver
EH233_RS11835	COG0745	RESPONSE REGULATOR receiver
EH233_RS11850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EH233_RS11855	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EH233_RS11875	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EH233_RS11885	COG0039	L-malate dehydrogenase activity
EH233_RS11895	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EH233_RS11905	COG0436	Aminotransferase
EH233_RS11920	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EH233_RS11925	COG1530	ribonuclease E activity
EH233_RS11930	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EH233_RS11945	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EH233_RS11950	COG0051	transcription antitermination factor activity, RNA binding
EH233_RS11955	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EH233_RS11960	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EH233_RS11965	COG0049	tRNA binding
EH233_RS11970	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EH233_RS11975	COG0316	Belongs to the HesB IscA family
EH233_RS11980	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
EH233_RS11980	COG0662	Cupin 2, conserved barrel domain protein
EH233_RS11990	COG0070	glutamate synthase
EH233_RS11990	COG0069	glutamate synthase activity
EH233_RS11990	COG0067	glutamate synthase
EH233_RS12005	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EH233_RS12020	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EH233_RS12050	COG0538	isocitrate dehydrogenase activity
EH233_RS12055	COG0515	serine threonine protein kinase
EH233_RS12060	COG3842	ATPase activity
EH233_RS12075	COG4636	protein conserved in cyanobacteria
EH233_RS12085	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
EH233_RS12115	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EH233_RS12135	COG2319	Wd-40 repeat
EH233_RS12135	COG1672	PFAM Archaeal ATPase
EH233_RS12170	COG2226	methyltransferase
EH233_RS12175	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EH233_RS12180	COG0569	domain protein
EH233_RS12190	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
EH233_RS12200	COG0792	nuclease activity
EH233_RS12225	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
EH233_RS12225	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EH233_RS12230	COG1562	ergosterol biosynthetic process
EH233_RS12275	COG0651	ATP synthesis coupled electron transport
EH233_RS12280	COG1006	Multisubunit Na H antiporter MnhC subunit
EH233_RS12285	COG1994	Peptidase M50
EH233_RS12285	COG0517	IMP dehydrogenase activity
EH233_RS12290	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EH233_RS12295	COG2202	Pas domain
EH233_RS12295	COG2205	protein histidine kinase activity
EH233_RS12305	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EH233_RS12310	COG1028	Short-chain dehydrogenase reductase Sdr
EH233_RS12315	COG2205	protein histidine kinase activity
EH233_RS12315	COG0784	Response regulator, receiver
EH233_RS12330	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EH233_RS12335	COG0297	glycogen (starch) synthase activity
EH233_RS12340	COG0181	hydroxymethylbilane synthase activity
EH233_RS12350	COG1803	Methylglyoxal synthase
EH233_RS12350	COG1597	lipid kinase activity
EH233_RS12360	COG0157	Belongs to the NadC ModD family
EH233_RS12365	COG1361	Conserved repeat domain
EH233_RS12375	COG2326	polyphosphate kinase activity
EH233_RS12380	COG0724	RNA recognition motif
EH233_RS12390	COG2226	methyltransferase
EH233_RS12405	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EH233_RS12410	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
EH233_RS12415	COG1959	2 iron, 2 sulfur cluster binding
EH233_RS12450	COG0346	lactoylglutathione lyase activity
EH233_RS12455	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EH233_RS12460	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EH233_RS12475	COG1295	ribonuclease BN
EH233_RS12495	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EH233_RS12520	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EH233_RS12550	COG0667	Aldo Keto reductase
EH233_RS12610	COG0405	Gamma-glutamyltransferase
EH233_RS12625	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EH233_RS12635	COG4651	solute:proton antiporter activity
EH233_RS12635	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EH233_RS12645	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EH233_RS12650	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
EH233_RS12650	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
EH233_RS12665	COG0571	ribonuclease III activity
EH233_RS12675	COG4249	Peptidase C14 caspase catalytic subunit p20
EH233_RS12675	COG2319	Wd-40 repeat
EH233_RS12700	COG0793	Belongs to the peptidase S41A family
EH233_RS12705	COG1215	transferase activity, transferring glycosyl groups
EH233_RS12775	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EH233_RS12785	COG0671	phosphoesterase, PA-phosphatase related
EH233_RS12790	COG0308	aminopeptidase N
EH233_RS12800	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EH233_RS12830	COG0438	transferase activity, transferring glycosyl groups
EH233_RS12835	COG1132	(ABC) transporter
EH233_RS12850	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EH233_RS12855	COG0359	binds to the 23S rRNA
EH233_RS12860	COG1372	Participates in initiation and elongation during chromosome replication
EH233_RS12860	COG0305	Participates in initiation and elongation during chromosome replication
EH233_RS12860	COG1372	Participates in initiation and elongation during chromosome replication
EH233_RS12860	COG0305	Participates in initiation and elongation during chromosome replication
EH233_RS12895	COG4242	Belongs to the peptidase S51 family
EH233_RS12900	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EH233_RS12930	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
EH233_RS13010	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EH233_RS13015	COG1357	PFAM Pentapeptide repeats (8 copies)
EH233_RS13015	COG0515	serine threonine protein kinase
EH233_RS13025	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
EH233_RS13030	COG3850	Histidine kinase
EH233_RS13030	COG2205	protein histidine kinase activity
EH233_RS13030	COG4999	Histidine kinase
EH233_RS13030	COG3437	response regulator, receiver
EH233_RS13050	COG0475	glutathione-regulated potassium exporter activity
EH233_RS13055	COG0347	Belongs to the P(II) protein family
EH233_RS13070	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EH233_RS13085	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EH233_RS13095	COG0488	(ABC) transporter
EH233_RS13110	COG1132	(ABC) transporter
EH233_RS13120	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
EH233_RS13145	COG1606	tRNA processing
EH233_RS13150	COG0784	Response regulator, receiver
EH233_RS13150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EH233_RS13150	COG2198	Histidine kinase
EH233_RS13150	COG2205	protein histidine kinase activity
EH233_RS13165	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EH233_RS13170	COG0784	Response regulator, receiver
EH233_RS13175	COG5001	Diguanylate cyclase
EH233_RS13175	COG2203	Gaf domain
EH233_RS13175	COG3706	GGDEF domain
EH233_RS13175	COG4251	negative regulation of phosphorylation
EH233_RS13180	COG5002	protein histidine kinase activity
EH233_RS13195	COG0110	maltose O-acetyltransferase activity
EH233_RS13225	COG0180	Tryptophanyl-tRNA synthetase
EH233_RS13255	COG0473	3-isopropylmalate dehydrogenase activity
EH233_RS13265	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EH233_RS13280	COG0525	valine-tRNA ligase activity
EH233_RS13285	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EH233_RS13290	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
EH233_RS13310	COG2239	Acts as a magnesium transporter
EH233_RS13330	COG2205	protein histidine kinase activity
EH233_RS13330	COG2202	Pas domain
EH233_RS13345	COG0735	belongs to the Fur family
EH233_RS13350	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EH233_RS13355	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EH233_RS13360	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EH233_RS13395	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EH233_RS13410	COG2815	serine threonine protein kinase
EH233_RS13410	COG0515	serine threonine protein kinase
EH233_RS13430	COG5002	protein histidine kinase activity
EH233_RS13440	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EH233_RS13485	COG0662	Cupin 2, conserved barrel domain protein
EH233_RS13485	COG2207	Transcriptional regulator
EH233_RS13535	COG2274	protein secretion by the type I secretion system
EH233_RS13545	COG0640	Transcriptional regulator
EH233_RS13565	COG0438	transferase activity, transferring glycosyl groups
EH233_RS13610	COG1193	negative regulation of DNA recombination
EH233_RS13620	COG0516	GMP reductase activity
EH233_RS13625	COG3118	belongs to the thioredoxin family
EH233_RS13650	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EH233_RS13655	COG0489	protein tyrosine kinase activity
EH233_RS13675	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EH233_RS13690	COG0717	Belongs to the dCTP deaminase family
EH233_RS13700	COG0563	adenylate kinase activity
EH233_RS13705	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EH233_RS13715	COG1127	ABC transporter
EH233_RS13725	COG0784	Response regulator, receiver
EH233_RS13725	COG2205	protein histidine kinase activity
EH233_RS13735	COG0728	peptidoglycan biosynthetic process
EH233_RS13740	COG1357	PFAM Pentapeptide repeats (8 copies)
EH233_RS13745	COG1316	TRANSCRIPTIONal
EH233_RS13755	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EH233_RS13760	COG1131	(ABC) transporter
EH233_RS13770	COG2815	serine threonine protein kinase
EH233_RS13770	COG0515	serine threonine protein kinase
EH233_RS13810	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
EH233_RS13815	COG0009	L-threonylcarbamoyladenylate synthase
EH233_RS13830	COG0514	ATP-dependent DNA helicase (RecQ)
EH233_RS13850	COG0628	permease
EH233_RS13855	COG1051	belongs to the nudix hydrolase family
EH233_RS13865	COG2897	thiosulfate sulfurtransferase activity
EH233_RS13870	COG4804	nuclease activity
EH233_RS13875	COG1160	GTP binding
EH233_RS13885	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
EH233_RS13890	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EH233_RS13895	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EH233_RS13900	COG0581	inorganic phosphate transmembrane transporter activity
EH233_RS13905	COG0573	inorganic phosphate transmembrane transporter activity
EH233_RS13910	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EH233_RS13915	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EH233_RS13920	COG2197	response regulator
EH233_RS13955	COG0154	amidase activity
EH233_RS13990	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EH233_RS14000	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EH233_RS14005	COG0583	DNA-binding transcription factor activity
EH233_RS14010	COG3659	wide pore channel activity
EH233_RS14030	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EH233_RS14035	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EH233_RS14040	COG1116	anion transmembrane transporter activity
EH233_RS14040	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EH233_RS14045	COG1116	anion transmembrane transporter activity
EH233_RS14050	COG0243	molybdopterin cofactor binding
EH233_RS14095	COG4106	trans-aconitate 2-methyltransferase activity
EH233_RS14105	COG0247	lactate metabolic process
EH233_RS14110	COG0277	FAD linked oxidase domain protein
EH233_RS14160	COG0006	proline dipeptidase activity
EH233_RS14170	COG0398	Pfam SNARE associated Golgi protein
EH233_RS14190	COG5002	protein histidine kinase activity
EH233_RS14190	COG0784	Response regulator, receiver
EH233_RS14210	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EH233_RS14215	COG1253	flavin adenine dinucleotide binding
EH233_RS14220	COG1981	membrane
EH233_RS14225	COG0312	modulator of DNA gyrase
EH233_RS14230	COG0312	modulator of DNA gyrase
EH233_RS14235	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EH233_RS14235	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EH233_RS14240	COG0509	glycine decarboxylation via glycine cleavage system
EH233_RS14245	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EH233_RS14250	COG1357	PFAM Pentapeptide repeats (8 copies)
EH233_RS14275	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EH233_RS14285	COG0398	Pfam SNARE associated Golgi protein
EH233_RS14290	COG0784	Response regulator, receiver
EH233_RS14305	COG0395	ABC-type sugar transport system, permease component
EH233_RS14310	COG2010	Cytochrome c
EH233_RS14315	COG3794	PFAM blue (type 1) copper domain protein
EH233_RS14340	COG0025	NhaP-type Na H and K H
EH233_RS14345	COG1408	metallophosphoesterase
EH233_RS14350	COG1408	metallophosphoesterase
EH233_RS14360	COG0484	heat shock protein binding
EH233_RS14385	COG0628	permease
EH233_RS14390	COG0204	Acyl-transferase
EH233_RS14390	COG0318	PFAM AMP-dependent synthetase and ligase
EH233_RS14395	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EH233_RS14400	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EH233_RS14405	COG0416	fatty acid biosynthetic process
EH233_RS14440	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EH233_RS14445	COG1061	Type III restriction enzyme res subunit
EH233_RS14550	COG0305	Participates in initiation and elongation during chromosome replication
EH233_RS14550	COG1372	Participates in initiation and elongation during chromosome replication
EH233_RS14710	COG0515	serine threonine protein kinase
EH233_RS14710	COG1357	PFAM Pentapeptide repeats (8 copies)
EH233_RS14715	COG2319	Wd-40 repeat
EH233_RS14715	COG3903	Transcriptional regulator
EH233_RS14730	COG2197	response regulator
EH233_RS14815	COG0739	heme binding
EH233_RS14930	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EH233_RS14975	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
EH233_RS14995	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EH233_RS15005	COG0739	heme binding
EH233_RS15015	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EH233_RS15025	COG3118	belongs to the thioredoxin family
EH233_RS15030	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EH233_RS15045	COG1131	(ABC) transporter
EH233_RS15060	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EH233_RS15070	COG1492	cobalamin metabolic process
EH233_RS15090	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
EH233_RS15105	COG0316	Belongs to the HesB IscA family
EH233_RS15120	COG1090	epimerase
EH233_RS15125	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
EH233_RS15155	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EH233_RS15175	COG3266	domain, Protein
EH233_RS15175	COG0515	serine threonine protein kinase
EH233_RS15180	COG0515	serine threonine protein kinase
EH233_RS15210	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EH233_RS15250	COG3321	synthase
EH233_RS15250	COG0604	alcohol dehydrogenase
EH233_RS15260	COG0515	serine threonine protein kinase
EH233_RS15260	COG1357	PFAM Pentapeptide repeats (8 copies)
EH233_RS15265	COG1136	(ABC) transporter
EH233_RS15320	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EH233_RS15325	COG1473	amidohydrolase
EH233_RS15370	COG5002	protein histidine kinase activity
EH233_RS15385	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EH233_RS15415	COG2897	thiosulfate sulfurtransferase activity
EH233_RS15420	COG2391	methyltransferase activity
EH233_RS15425	COG2873	o-acetylhomoserine
EH233_RS15430	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EH233_RS15440	COG0489	protein tyrosine kinase activity
EH233_RS15490	COG3540	Alkaline phosphatase
EH233_RS15515	COG0784	Response regulator, receiver
EH233_RS15515	COG2205	protein histidine kinase activity
EH233_RS15530	COG1116	anion transmembrane transporter activity
EH233_RS15535	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EH233_RS15540	COG3659	wide pore channel activity
EH233_RS15545	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EH233_RS15550	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EH233_RS15565	COG0667	Aldo Keto reductase
EH233_RS15570	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EH233_RS15585	COG3706	GGDEF domain
EH233_RS15585	COG5001	Diguanylate cyclase
EH233_RS15585	COG4251	negative regulation of phosphorylation
EH233_RS15585	COG2203	Gaf domain
EH233_RS15605	COG0412	Dienelactone hydrolase
EH233_RS15610	COG0778	Nitroreductase
EH233_RS15615	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EH233_RS15620	COG0626	cystathionine gamma-synthase activity
EH233_RS15665	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EH233_RS15675	COG0811	peptide transport
EH233_RS15680	COG0848	biopolymer transport protein
EH233_RS15685	COG0768	penicillin binding
EH233_RS15695	COG3842	ATPase activity
EH233_RS15700	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EH233_RS15720	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EH233_RS15725	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EH233_RS15745	COG0714	Associated with various cellular activities
EH233_RS15765	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
EH233_RS15775	COG0748	coenzyme F420 binding
EH233_RS15795	COG0438	transferase activity, transferring glycosyl groups
EH233_RS15800	COG0583	DNA-binding transcription factor activity
EH233_RS15820	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EH233_RS15845	COG1834	amidinotransferase
EH233_RS15870	COG0860	N-Acetylmuramoyl-L-alanine amidase
EH233_RS15875	COG0504	CTP synthase activity
EH233_RS15885	COG1940	carbohydrate kinase activity
EH233_RS15895	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EH233_RS15910	COG0124	histidyl-tRNA synthetase
EH233_RS15915	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EH233_RS15940	COG2909	trisaccharide binding
EH233_RS15950	COG0516	GMP reductase activity
EH233_RS15950	COG0517	IMP dehydrogenase activity
EH233_RS15955	COG0494	nUDIX hydrolase
EH233_RS15965	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EH233_RS15970	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EH233_RS15975	COG0783	Belongs to the Dps family
EH233_RS15985	COG1899	peptidyl-lysine modification to peptidyl-hypusine
EH233_RS16010	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EH233_RS16015	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EH233_RS16025	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EH233_RS16030	COG0058	SHG alpha-glucan phosphorylase activity
EH233_RS16035	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EH233_RS16050	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
EH233_RS16055	COG0401	homolog of Blt101
EH233_RS16060	COG0023	Translation Initiation Factor
EH233_RS16065	COG0133	tryptophan synthase activity
EH233_RS16080	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
EH233_RS16095	COG0745	RESPONSE REGULATOR receiver
EH233_RS16100	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EH233_RS16110	COG0702	epimerase
EH233_RS16115	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EH233_RS16120	COG0745	RESPONSE REGULATOR receiver
EH233_RS16140	COG0134	indole-3-glycerol-phosphate synthase activity
EH233_RS16145	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EH233_RS16200	COG2197	response regulator
EH233_RS16205	COG5001	Diguanylate cyclase
EH233_RS16210	COG5002	protein histidine kinase activity
EH233_RS16210	COG2198	Histidine kinase
EH233_RS16210	COG0784	Response regulator, receiver
EH233_RS16215	COG0784	Response regulator, receiver
EH233_RS16215	COG5002	protein histidine kinase activity
EH233_RS16235	COG2205	protein histidine kinase activity
EH233_RS16235	COG0784	Response regulator, receiver
EH233_RS16235	COG5002	protein histidine kinase activity
EH233_RS16245	COG0745	RESPONSE REGULATOR receiver
EH233_RS16255	COG1215	transferase activity, transferring glycosyl groups
EH233_RS16275	COG0300	oxidoreductase activity
EH233_RS16285	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EH233_RS16290	COG2226	methyltransferase
EH233_RS16300	COG0402	S-adenosylhomocysteine deaminase activity
EH233_RS16345	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EH233_RS16355	COG4636	protein conserved in cyanobacteria
EH233_RS16370	COG1830	Aldolase
EH233_RS16380	COG3266	domain, Protein
EH233_RS16380	COG0515	serine threonine protein kinase
EH233_RS16385	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EH233_RS16390	COG2226	methyltransferase
EH233_RS16420	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EH233_RS16425	COG0592	DNA-directed DNA polymerase activity
EH233_RS16505	COG1205	dead DEAH box helicase
EH233_RS16505	COG1111	helicase
EH233_RS16730	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EH233_RS16730	COG0515	serine threonine protein kinase
EH233_RS16735	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EH233_RS16735	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
EH233_RS16805	COG3706	GGDEF domain
EH233_RS16815	COG1902	pentaerythritol trinitrate reductase activity
EH233_RS16820	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EH233_RS16825	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EH233_RS16830	COG2076	Multidrug Resistance protein
EH233_RS16835	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EH233_RS16880	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EH233_RS16910	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EH233_RS16920	COG0659	secondary active sulfate transmembrane transporter activity
EH233_RS16990	COG1715	Restriction endonuclease
EH233_RS17095	COG1061	Type III restriction enzyme res subunit
EH233_RS17100	COG0583	DNA-binding transcription factor activity
EH233_RS17105	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EH233_RS17110	COG3540	Alkaline phosphatase
EH233_RS17115	COG0577	efflux transmembrane transporter activity
EH233_RS17115	COG1136	(ABC) transporter
EH233_RS17130	COG1695	Transcriptional regulator
EH233_RS17150	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EH233_RS17155	COG3150	esterase
EH233_RS17160	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EH233_RS17190	COG0497	DNA recombination
EH233_RS17195	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EH233_RS17210	COG0628	permease
EH233_RS17225	COG3631	Ketosteroid isomerase-related protein
EH233_RS17230	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EH233_RS17235	COG0546	phosphoglycolate phosphatase activity
EH233_RS17245	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EH233_RS17260	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EH233_RS17265	COG4956	integral membrane protein (PIN domain superfamily)
EH233_RS17270	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EH233_RS17270	COG0072	phenylalanine-tRNA ligase activity
EH233_RS17285	COG1473	amidohydrolase
EH233_RS17290	COG1215	transferase activity, transferring glycosyl groups
EH233_RS17295	COG1742	UPF0060 membrane protein
EH233_RS17315	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EH233_RS17330	COG2207	Transcriptional regulator
EH233_RS17340	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EH233_RS17345	COG2814	Major facilitator Superfamily
EH233_RS17350	COG3659	wide pore channel activity
EH233_RS17395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EH233_RS17445	COG5285	phytanoyl-CoA dioxygenase
EH233_RS17490	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EH233_RS17490	COG0574	Belongs to the PEP-utilizing enzyme family
EH233_RS17510	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EH233_RS17520	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EH233_RS17525	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EH233_RS17530	COG5002	protein histidine kinase activity
EH233_RS17540	COG4251	negative regulation of phosphorylation
EH233_RS17545	COG0784	Response regulator, receiver
EH233_RS17550	COG2205	protein histidine kinase activity
EH233_RS17570	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EH233_RS17575	COG2217	Heavy metal translocating P-type atpase
EH233_RS17580	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EH233_RS17595	COG0628	permease
EH233_RS17610	COG5002	protein histidine kinase activity
EH233_RS17620	COG1357	PFAM Pentapeptide repeats (8 copies)
EH233_RS17620	COG0515	serine threonine protein kinase
EH233_RS17655	COG0463	Glycosyl transferase, family 2
EH233_RS17655	COG1216	Glycosyl transferase, family 2
EH233_RS17665	COG0110	maltose O-acetyltransferase activity
EH233_RS17750	COG3655	Transcriptional regulator
EH233_RS17790	COG0557	exoribonuclease II activity
EH233_RS17795	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EH233_RS17800	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EH233_RS17820	COG0443	Heat shock 70 kDa protein
EH233_RS17840	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EH233_RS17855	COG0346	lactoylglutathione lyase activity
EH233_RS17860	COG2304	oxidoreductase activity
EH233_RS17865	COG2304	oxidoreductase activity
EH233_RS17870	COG0740	serine-type endopeptidase activity
EH233_RS17875	COG0740	serine-type endopeptidase activity
EH233_RS17890	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EH233_RS17900	COG4948	Mandelate Racemase Muconate Lactonizing
EH233_RS17905	COG0494	nUDIX hydrolase
EH233_RS17915	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EH233_RS17915	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EH233_RS17920	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EH233_RS17925	COG0148	phosphopyruvate hydratase activity
EH233_RS17935	COG0351	phosphomethylpyrimidine kinase
EH233_RS17995	COG0697	spore germination
EH233_RS18005	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EH233_RS18020	COG1012	belongs to the aldehyde dehydrogenase family
EH233_RS18025	COG0515	serine threonine protein kinase
EH233_RS18025	COG2815	serine threonine protein kinase
EH233_RS18045	COG0445	tRNA wobble uridine modification
EH233_RS18070	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
EH233_RS18080	COG1404	Belongs to the peptidase S8 family
EH233_RS18090	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
EH233_RS18100	COG0484	heat shock protein binding
EH233_RS18110	COG0450	alkyl hydroperoxide reductase
EH233_RS18130	COG4585	Histidine kinase
EH233_RS18135	COG2197	response regulator
EH233_RS18145	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EH233_RS18170	COG0440	acetolactate synthase activity
EH233_RS18185	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EH233_RS18220	COG4172	Belongs to the ABC transporter superfamily
EH233_RS18225	COG0629	single-stranded DNA binding
EH233_RS18235	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
EH233_RS18250	COG3842	ATPase activity
EH233_RS18260	COG3631	Ketosteroid isomerase-related protein
EH233_RS18265	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EH233_RS18270	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EH233_RS18275	COG0412	Dienelactone hydrolase
EH233_RS18285	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EH233_RS18290	COG0482	sulfurtransferase activity
EH233_RS18300	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EH233_RS18300	COG2124	cytochrome p450
EH233_RS18320	COG3659	wide pore channel activity
EH233_RS18360	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
EH233_RS18375	COG1271	oxidase subunit
EH233_RS18380	COG1294	oxidase, subunit
EH233_RS18405	COG1910	domain protein
EH233_RS18410	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EH233_RS18425	COG1122	ATPase activity
EH233_RS18430	COG1309	transcriptional regulator
EH233_RS18440	COG0778	Nitroreductase
EH233_RS18480	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
EH233_RS18485	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
EH233_RS18505	COG0412	Dienelactone hydrolase
EH233_RS18510	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EH233_RS18530	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
EH233_RS18550	COG0768	penicillin binding
EH233_RS18575	COG0012	GTP binding
EH233_RS18595	COG0363	glucosamine-6-phosphate deaminase activity
EH233_RS18600	COG0546	phosphoglycolate phosphatase activity
EH233_RS18605	COG5002	protein histidine kinase activity
EH233_RS18605	COG0784	Response regulator, receiver
EH233_RS18610	COG0731	radical SAM domain protein
EH233_RS18620	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
EH233_RS18625	COG0830	nickel cation binding
EH233_RS18630	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
EH233_RS18635	COG0492	ferredoxin-NADP+ reductase activity
EH233_RS18640	COG1175	transmembrane transport
EH233_RS18650	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
EH233_RS18660	COG0330	HflC and HflK could
EH233_RS18665	COG0724	RNA recognition motif
EH233_RS18670	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EH233_RS18675	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
EH233_RS18700	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
EH233_RS18710	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EH233_RS18715	COG0589	response to stress
EH233_RS18740	COG1034	ATP synthesis coupled electron transport
EH233_RS18760	COG1122	ATPase activity
EH233_RS18765	COG3688	RNA-binding protein containing a PIN domain
EH233_RS18785	COG0187	DNA topoisomerase II activity
EH233_RS18785	COG1372	Participates in initiation and elongation during chromosome replication
EH233_RS18790	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EH233_RS18795	COG0515	serine threonine protein kinase
EH233_RS18795	COG3266	domain, Protein
EH233_RS18800	COG0277	FAD linked oxidase domain protein
EH233_RS18810	COG1649	PFAM Uncharacterised BCR, COG1649
EH233_RS18820	COG4251	negative regulation of phosphorylation
EH233_RS18820	COG3706	GGDEF domain
EH233_RS18820	COG5001	Diguanylate cyclase
EH233_RS18820	COG2203	Gaf domain
EH233_RS18840	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
EH233_RS18845	COG1357	PFAM Pentapeptide repeats (8 copies)
EH233_RS18845	COG0515	serine threonine protein kinase
EH233_RS18865	COG0395	ABC-type sugar transport system, permease component
EH233_RS18870	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
EH233_RS18875	COG5322	oxidoreductase activity
EH233_RS18880	COG0825	malonyl-CoA metabolic process
EH233_RS18885	COG0300	oxidoreductase activity
EH233_RS18890	COG0302	gtp cyclohydrolase
EH233_RS18895	COG0135	phosphoribosylanthranilate isomerase activity
EH233_RS18930	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EH233_RS18945	COG1309	transcriptional regulator
EH233_RS18950	COG0335	large ribosomal subunit rRNA binding
EH233_RS18960	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EH233_RS18965	COG0250	Participates in transcription elongation, termination and antitermination
EH233_RS18970	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EH233_RS18975	COG0081	regulation of translation
EH233_RS18980	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EH233_RS18985	COG0222	ribosome binding
EH233_RS18995	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EH233_RS19005	COG4221	oxidoreductase activity
EH233_RS19075	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EH233_RS19075	COG1017	nitric oxide dioxygenase activity
EH233_RS19085	COG2133	pyrroloquinoline quinone binding
EH233_RS19095	COG0783	Belongs to the Dps family
EH233_RS19100	COG4572	Cation transport regulator
EH233_RS19125	COG1136	(ABC) transporter
EH233_RS19125	COG0577	efflux transmembrane transporter activity
EH233_RS19130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EH233_RS19135	COG1136	(ABC) transporter
EH233_RS19140	COG1136	(ABC) transporter
EH233_RS19140	COG0577	efflux transmembrane transporter activity
EH233_RS19155	COG1151	hydroxylamine reductase activity
EH233_RS19160	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EH233_RS19165	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EH233_RS19180	COG3240	lipase activity
EH233_RS19190	COG0863	Belongs to the N(4) N(6)-methyltransferase family
EH233_RS19210	COG1361	Conserved repeat domain
EH233_RS19235	COG1022	Amp-dependent synthetase and ligase
EH233_RS19250	COG2205	protein histidine kinase activity
EH233_RS19255	COG2203	Gaf domain
EH233_RS19255	COG3706	GGDEF domain
EH233_RS19255	COG5001	Diguanylate cyclase
EH233_RS19255	COG4251	negative regulation of phosphorylation
EH233_RS19280	COG2201	protein-glutamate methylesterase activity
EH233_RS19285	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EH233_RS19315	COG5002	protein histidine kinase activity
EH233_RS19350	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EH233_RS19360	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
EH233_RS19365	COG0375	protein maturation
EH233_RS19380	COG0409	Hydrogenase expression formation protein
EH233_RS19445	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EH233_RS19450	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
EH233_RS19455	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EH233_RS19460	COG0475	glutathione-regulated potassium exporter activity
EH233_RS19460	COG0589	response to stress
EH233_RS19475	COG0772	Belongs to the SEDS family
EH233_RS19480	COG0489	protein tyrosine kinase activity
EH233_RS19490	COG0408	coproporphyrinogen oxidase activity
EH233_RS19520	COG0848	biopolymer transport protein
EH233_RS19525	COG0811	peptide transport
EH233_RS19535	COG1132	(ABC) transporter
EH233_RS19550	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EH233_RS19550	COG0574	Belongs to the PEP-utilizing enzyme family
EH233_RS19555	COG0589	response to stress
EH233_RS19560	COG0826	peptidase U32
EH233_RS19565	COG0443	Heat shock 70 kDa protein
EH233_RS19615	COG0523	cobalamin synthesis protein
EH233_RS19625	COG0312	modulator of DNA gyrase
EH233_RS19630	COG0237	dephospho-CoA kinase activity
EH233_RS19650	COG2208	phosphoserine phosphatase activity
EH233_RS19655	COG0552	protein localization to endoplasmic reticulum
EH233_RS19660	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EH233_RS19695	COG1215	transferase activity, transferring glycosyl groups
EH233_RS19700	COG1215	transferase activity, transferring glycosyl groups
EH233_RS19725	COG1722	exodeoxyribonuclease VII activity
EH233_RS19730	COG1570	exodeoxyribonuclease VII activity
EH233_RS19735	COG0523	cobalamin synthesis protein
EH233_RS19740	COG0215	cysteine-tRNA ligase activity
EH233_RS19750	COG0312	modulator of DNA gyrase
EH233_RS19755	COG3852	Histidine kinase
EH233_RS19760	COG1366	Belongs to the anti-sigma-factor antagonist family
EH233_RS19765	COG0745	RESPONSE REGULATOR receiver
EH233_RS19800	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EH233_RS19810	COG0539	negative regulation of cytoplasmic translation
EH233_RS19815	COG0412	Dienelactone hydrolase
EH233_RS19820	COG2188	Transcriptional regulator
EH233_RS19860	COG3540	Alkaline phosphatase
EH233_RS19865	COG0300	oxidoreductase activity
EH233_RS19865	COG3000	fatty acid hydroxylase
EH233_RS19880	COG0584	glycerophosphoryl diester phosphodiesterase
EH233_RS19890	COG0154	amidase activity
EH233_RS19900	COG0587	DNA-directed DNA polymerase activity
EH233_RS19930	COG4251	negative regulation of phosphorylation
EH233_RS19930	COG5001	Diguanylate cyclase
EH233_RS19930	COG2203	Gaf domain
EH233_RS19930	COG3706	GGDEF domain
EH233_RS19950	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
EH233_RS19970	COG1215	transferase activity, transferring glycosyl groups
EH233_RS19985	COG0438	transferase activity, transferring glycosyl groups
EH233_RS20005	COG0489	protein tyrosine kinase activity
EH233_RS20010	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EH233_RS20020	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EH233_RS20045	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
EH233_RS20050	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EH233_RS20050	COG0519	Catalyzes the synthesis of GMP from XMP
EH233_RS20065	COG0730	response to heat
EH233_RS20080	COG1473	amidohydrolase
EH233_RS20085	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EH233_RS20120	COG1285	pathogenesis
EH233_RS20125	COG0431	NADPH-dependent FMN reductase
EH233_RS20145	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EH233_RS20165	COG0167	dihydroorotate dehydrogenase activity
EH233_RS20180	COG1695	Transcriptional regulator
EH233_RS20185	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EH233_RS20195	COG0217	transcriptional regulatory protein
EH233_RS20225	COG0577	efflux transmembrane transporter activity
EH233_RS20225	COG1136	(ABC) transporter
EH233_RS20235	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
EH233_RS20240	COG2211	Major facilitator Superfamily
EH233_RS20245	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EH233_RS20250	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EH233_RS20255	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EH233_RS20275	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EH233_RS20285	COG4294	response to UV
EH233_RS20290	COG0443	Heat shock 70 kDa protein
EH233_RS20305	COG1049	propionate catabolic process, 2-methylcitrate cycle
EH233_RS20310	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EH233_RS20320	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EH233_RS20330	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EH233_RS20360	COG0628	permease
EH233_RS20365	COG0259	pyridoxamine-phosphate oxidase activity
EH233_RS20380	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EH233_RS20385	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EH233_RS20400	COG0163	prenyltransferase activity
EH233_RS20405	COG0557	exoribonuclease II activity
EH233_RS20415	COG0740	serine-type endopeptidase activity
EH233_RS20425	COG1331	Highly conserved protein containing a thioredoxin domain
EH233_RS20445	COG0746	molybdenum cofactor guanylyltransferase activity
EH233_RS20460	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EH233_RS20470	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
EH233_RS20475	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EH233_RS20500	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EH233_RS20505	COG3536	Protein conserved in bacteria
EH233_RS20520	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EH233_RS20525	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EH233_RS20535	COG0138	bifunctional purine biosynthesis protein purh
EH233_RS20550	COG3546	catalase activity
EH233_RS20555	COG2261	transglycosylase associated protein
EH233_RS20560	COG4232	protein-disulfide reductase activity
EH233_RS20565	COG1333	cytochrome c biogenesis protein
EH233_RS20580	COG5398	heme oxygenase
EH233_RS20585	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EH233_RS20605	COG2327	Polysaccharide pyruvyl transferase
EH233_RS20610	COG0617	tRNA 3'-terminal CCA addition
EH233_RS20620	COG1214	PFAM Peptidase M22, glycoprotease
EH233_RS20625	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EH233_RS20645	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EH233_RS20650	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
EH233_RS20655	COG1027	Aspartate ammonia-lyase
EH233_RS20660	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EH233_RS20680	COG0018	arginyl-trna synthetase
EH233_RS20700	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EH233_RS20720	COG0438	transferase activity, transferring glycosyl groups
EH233_RS20740	COG0438	transferase activity, transferring glycosyl groups
EH233_RS20750	COG1845	cytochrome c oxidase, subunit III
EH233_RS20755	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EH233_RS20760	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EH233_RS20785	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
EH233_RS20790	COG2211	Major facilitator Superfamily
EH233_RS20795	COG0515	serine threonine protein kinase
EH233_RS20795	COG2815	serine threonine protein kinase
EH233_RS20800	COG0724	RNA recognition motif
EH233_RS20805	COG0010	Belongs to the arginase family
EH233_RS20810	COG3854	ATPases associated with a variety of cellular activities
EH233_RS20845	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EH233_RS20850	COG3621	Patatin-like phospholipase
EH233_RS20855	COG0802	atpase or kinase
EH233_RS20865	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EH233_RS20870	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EH233_RS20890	COG0546	phosphoglycolate phosphatase activity
EH233_RS20895	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EH233_RS20910	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EH233_RS20915	COG0667	Aldo Keto reductase
EH233_RS20945	COG2072	flavoprotein involved in K transport
EH233_RS20975	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EH233_RS20990	COG1215	transferase activity, transferring glycosyl groups
EH233_RS20995	COG1132	(ABC) transporter
EH233_RS21005	COG0489	protein tyrosine kinase activity
EH233_RS21015	COG0460	homoserine dehydrogenase
EH233_RS21045	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EH233_RS21050	COG0579	oxidoreductase
EH233_RS21055	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EH233_RS21070	COG4245	von Willebrand factor, type A
EH233_RS21100	COG2274	protein secretion by the type I secretion system
EH233_RS21125	COG1032	radical SAM domain protein
EH233_RS21135	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EH233_RS21140	COG1733	regulation of RNA biosynthetic process
EH233_RS21160	COG0569	domain protein
EH233_RS21170	COG0025	NhaP-type Na H and K H
EH233_RS21200	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EH233_RS21215	COG2226	methyltransferase
EH233_RS21225	COG1013	pyruvate-flavodoxin oxidoreductase activity
EH233_RS21225	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EH233_RS21225	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EH233_RS21225	COG0674	pyruvate-flavodoxin oxidoreductase activity
EH233_RS21265	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
EH233_RS21275	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
EH233_RS21280	COG3977	Valine--pyruvate aminotransferase
EH233_RS21290	COG2205	protein histidine kinase activity
EH233_RS21295	COG2205	protein histidine kinase activity
EH233_RS21295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EH233_RS21325	COG2205	protein histidine kinase activity
EH233_RS21340	COG3659	wide pore channel activity
EH233_RS21350	COG0515	serine threonine protein kinase
EH233_RS21350	COG1357	PFAM Pentapeptide repeats (8 copies)
EH233_RS21360	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EH233_RS21370	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EH233_RS21375	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EH233_RS21380	COG5002	protein histidine kinase activity
EH233_RS21385	COG2197	response regulator
EH233_RS21410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EH233_RS21450	COG1649	PFAM Uncharacterised BCR, COG1649
EH233_RS21460	COG0189	ligase activity
EH233_RS21460	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EH233_RS21485	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EH233_RS21505	COG1598	PFAM Uncharacterised protein family UPF0150
EH233_RS21510	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EH233_RS21530	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EH233_RS21535	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
EH233_RS21550	COG0745	RESPONSE REGULATOR receiver
EH233_RS21595	COG1120	ATPase activity
EH233_RS21625	COG1054	Belongs to the UPF0176 family
EH233_RS21630	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
EH233_RS21635	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EH233_RS21645	COG0561	phosphatase activity
EH233_RS21650	COG0632	four-way junction helicase activity
EH233_RS21655	COG0156	8-amino-7-oxononanoate synthase activity
EH233_RS21665	COG3903	Transcriptional regulator
EH233_RS21665	COG2319	Wd-40 repeat
EH233_RS21695	COG1846	Transcriptional regulator
EH233_RS21725	COG0631	protein serine/threonine phosphatase activity
EH233_RS21760	COG0515	serine threonine protein kinase
EH233_RS21760	COG3266	domain, Protein
EH233_RS21825	COG1475	DNA binding
EH233_RS21830	COG1192	Involved in chromosome partitioning
EH233_RS21865	COG1372	Participates in initiation and elongation during chromosome replication
EH233_RS21865	COG0305	Participates in initiation and elongation during chromosome replication
EH233_RS21865	COG0305	Participates in initiation and elongation during chromosome replication
EH233_RS21865	COG1372	Participates in initiation and elongation during chromosome replication
EH233_RS21925	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EH233_RS21925	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EH233_RS21960	COG1201	RNA secondary structure unwinding
EH233_RS21970	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EH233_RS21975	COG1116	anion transmembrane transporter activity
EH233_RS21975	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EH233_RS21985	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EH233_RS21995	COG0406	alpha-ribazole phosphatase activity
EH233_RS22000	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
EH233_RS22005	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EH233_RS22010	COG2048	Heterodisulfide reductase, subunit B
EH233_RS22015	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EH233_RS22020	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EH233_RS22025	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EH233_RS22060	COG2503	HAD superfamily, subfamily IIIB (Acid phosphatase)
EH233_RS22120	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EH233_RS22120	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EH233_RS22270	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EH233_RS22280	COG2082	Precorrin-8x methylmutase
EH233_RS22325	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EH233_RS22350	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EH233_RS22365	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EH233_RS22375	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EH233_RS22380	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
EH233_RS22385	COG2045	Belongs to the ComB family
EH233_RS22405	COG2205	protein histidine kinase activity
EH233_RS22450	COG0668	transmembrane transport
EH233_RS22460	COG0745	RESPONSE REGULATOR receiver
EH233_RS22470	COG5002	protein histidine kinase activity
EH233_RS22475	COG5002	protein histidine kinase activity
EH233_RS22485	COG0697	spore germination
EH233_RS22525	COG1309	transcriptional regulator
EH233_RS22540	COG0577	efflux transmembrane transporter activity
EH233_RS22540	COG1136	(ABC) transporter
EH233_RS22550	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EH233_RS22575	COG0840	transmembrane signaling receptor activity
EH233_RS22590	COG0784	Response regulator, receiver
EH233_RS22600	COG0037	tRNA processing
EH233_RS22610	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EH233_RS22630	COG0439	Biotin carboxylase
EH233_RS22645	COG0515	serine threonine protein kinase
EH233_RS22655	COG5001	Diguanylate cyclase
EH233_RS22655	COG3706	GGDEF domain
EH233_RS22655	COG2203	Gaf domain
EH233_RS22655	COG4251	negative regulation of phosphorylation
EH233_RS22665	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EH233_RS22680	COG0109	protoheme IX farnesyltransferase activity
EH233_RS22690	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EH233_RS22695	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EH233_RS22715	COG1216	Glycosyl transferase, family 2
EH233_RS22720	COG3206	protein involved in exopolysaccharide biosynthesis
EH233_RS22720	COG0489	protein tyrosine kinase activity
EH233_RS22780	COG2268	Band 7 protein
EH233_RS22795	COG2223	nitrite transmembrane transporter activity
EH233_RS22805	COG0456	acetyltransferase
EH233_RS22815	COG0662	Cupin 2, conserved barrel domain protein
EH233_RS22815	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
EH233_RS22835	COG4783	chaperone-mediated protein folding
EH233_RS22850	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EH233_RS22855	COG0667	Aldo Keto reductase
EH233_RS22880	COG0346	lactoylglutathione lyase activity
EH233_RS22885	COG0542	response to heat
EH233_RS22895	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EH233_RS22905	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EH233_RS22910	COG0793	Belongs to the peptidase S41A family
EH233_RS22920	COG0174	glutamine synthetase
EH233_RS22930	COG2226	methyltransferase
EH233_RS22950	COG0515	serine threonine protein kinase
EH233_RS22950	COG1357	PFAM Pentapeptide repeats (8 copies)
EH233_RS22955	COG1063	alcohol dehydrogenase
EH233_RS22970	COG3001	Fructosamine kinase
EH233_RS22995	COG0542	response to heat
EH233_RS23010	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
EH233_RS23020	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
EH233_RS23030	COG0784	Response regulator, receiver
EH233_RS23030	COG2198	Histidine kinase
EH233_RS23030	COG2205	protein histidine kinase activity
EH233_RS23055	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EH233_RS23060	COG0745	RESPONSE REGULATOR receiver
EH233_RS23065	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EH233_RS23070	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EH233_RS23075	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EH233_RS23080	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EH233_RS23090	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
EH233_RS23095	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EH233_RS23100	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EH233_RS23105	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EH233_RS23110	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EH233_RS23115	COG0511	ligase activity, forming carbon-carbon bonds
EH233_RS23120	COG0640	Transcriptional regulator
EH233_RS23130	COG0442	prolyl-tRNA aminoacylation
EH233_RS23140	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EH233_RS23155	COG2202	Pas domain
EH233_RS23155	COG3920	Histidine kinase
EH233_RS23165	COG2205	protein histidine kinase activity
EH233_RS23215	COG2884	Cell division ATP-binding protein ftsE
EH233_RS23225	COG2197	response regulator
EH233_RS23270	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EH233_RS23275	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EH233_RS23290	COG4636	protein conserved in cyanobacteria
EH233_RS23325	COG0419	ATPase involved in DNA repair
EH233_RS23355	COG0670	Belongs to the BI1 family
EH233_RS23380	COG1028	Short-chain dehydrogenase reductase Sdr
EH233_RS23380	COG3321	synthase
EH233_RS23380	COG0604	alcohol dehydrogenase
EH233_RS23390	COG0438	transferase activity, transferring glycosyl groups
EH233_RS23410	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EH233_RS23415	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EH233_RS23420	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
EH233_RS23460	COG1462	curli production assembly transport component CsgG
EH233_RS23520	COG0612	Peptidase, M16
EH233_RS23525	COG0612	Peptidase, M16
EH233_RS23540	COG0384	phenazine biosynthesis protein PhzF
EH233_RS23545	COG0006	proline dipeptidase activity
EH233_RS23580	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EH233_RS23585	COG0228	four-way junction DNA binding
EH233_RS23595	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EH233_RS23600	COG1702	phosphate starvation-inducible protein PhoH
EH233_RS23620	COG0095	Lipoate-protein ligase
EH233_RS23630	COG0542	response to heat
EH233_RS23640	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EH233_RS23655	COG0515	serine threonine protein kinase
EH233_RS23655	COG1357	PFAM Pentapeptide repeats (8 copies)
EH233_RS23680	COG0784	Response regulator, receiver
EH233_RS23680	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EH233_RS23685	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EH233_RS23690	COG0515	serine threonine protein kinase
EH233_RS23690	COG2815	serine threonine protein kinase
EH233_RS23705	COG1028	Short-chain dehydrogenase reductase Sdr
EH233_RS23720	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EH233_RS23730	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EH233_RS23740	COG0083	homoserine kinase activity
EH233_RS23760	COG1301	dicarboxylic acid transport
EH233_RS23775	COG1121	(ABC) transporter
EH233_RS23780	COG3443	Belongs to the bacterial solute-binding protein 9 family
EH233_RS23780	COG0803	Belongs to the bacterial solute-binding protein 9 family
EH233_RS23785	COG0113	porphobilinogen synthase activity
EH233_RS23790	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EH233_RS23800	COG0523	cobalamin synthesis protein
EH233_RS23805	COG2226	methyltransferase
EH233_RS23865	COG3659	wide pore channel activity
EH233_RS23880	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EH233_RS23925	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EH233_RS23950	COG0701	Predicted permease
EH233_RS23955	COG3852	Histidine kinase
EH233_RS23960	COG2084	Dehydrogenase
EH233_RS23970	COG2203	Gaf domain
EH233_RS23975	COG0392	lysyltransferase activity
EH233_RS23995	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
EH233_RS23995	COG0392	lysyltransferase activity
EH233_RS24000	COG0649	NAD binding
EH233_RS24005	COG0501	Belongs to the peptidase M48B family
EH233_RS24010	COG0275	rRNA processing
EH233_RS24015	COG4942	peptidase
EH233_RS24015	COG1388	LysM domain
EH233_RS24020	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EH233_RS24025	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
EH233_RS24030	COG0123	including yeast histone deacetylase and acetoin utilization protein
EH233_RS24040	COG0430	RNA-3'-phosphate cyclase activity
EH233_RS24050	COG1192	Involved in chromosome partitioning
EH233_RS24060	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EH233_RS24065	COG2201	protein-glutamate methylesterase activity
EH233_RS24080	COG0840	transmembrane signaling receptor activity
EH233_RS24080	COG2203	Gaf domain
EH233_RS24085	COG0784	Response regulator, receiver
EH233_RS24085	COG0643	Histidine kinase
EH233_RS24085	COG2198	Histidine kinase
EH233_RS24095	COG1741	Belongs to the pirin family
EH233_RS24100	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EH233_RS24115	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EH233_RS24140	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EH233_RS24145	COG3437	response regulator, receiver
EH233_RS24150	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EH233_RS24150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EH233_RS24175	COG0045	succinate-CoA ligase (ADP-forming) activity
EH233_RS24185	COG2988	succinylglutamate desuccinylase activity
EH233_RS24190	COG1770	oligopeptidase
EH233_RS24200	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EH233_RS24205	COG3320	Male sterility
EH233_RS24205	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EH233_RS24220	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EH233_RS24225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EH233_RS24235	COG1032	radical SAM domain protein
EH233_RS24245	COG0517	IMP dehydrogenase activity
EH233_RS24245	COG1994	Peptidase M50
EH233_RS24260	COG1028	Short-chain dehydrogenase reductase Sdr
EH233_RS24270	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EH233_RS24275	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EH233_RS24280	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
EH233_RS24285	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EH233_RS24290	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EH233_RS24305	COG0438	transferase activity, transferring glycosyl groups
EH233_RS24305	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EH233_RS24315	COG0501	Belongs to the peptidase M48B family
EH233_RS24335	COG0515	serine threonine protein kinase
EH233_RS24340	COG5002	protein histidine kinase activity
EH233_RS24410	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EH233_RS24420	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EH233_RS24445	COG1957	nucleoside hydrolase
EH233_RS24450	COG2197	response regulator
EH233_RS24455	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EH233_RS24460	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EH233_RS24470	COG0071	Belongs to the small heat shock protein (HSP20) family
EH233_RS24475	COG2076	Multidrug Resistance protein
EH233_RS24485	COG1131	(ABC) transporter
EH233_RS24495	COG0330	HflC and HflK could
EH233_RS24500	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EH233_RS24505	COG0149	triose-phosphate isomerase activity
EH233_RS24510	COG1160	GTP binding
EH233_RS24525	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EH233_RS24540	COG0113	porphobilinogen synthase activity
EH233_RS24545	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EH233_RS24560	COG0438	transferase activity, transferring glycosyl groups
EH233_RS24585	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EH233_RS24600	COG0131	Imidazoleglycerol-phosphate dehydratase
EH233_RS24605	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
EH233_RS24610	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EH233_RS24615	COG4372	Transposase
EH233_RS24630	COG1185	polyribonucleotide nucleotidyltransferase activity
EH233_RS24640	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EH233_RS24655	COG2319	Wd-40 repeat
EH233_RS24655	COG5635	Nacht domain
EH233_RS24655	COG2319	Wd-40 repeat
EH233_RS24655	COG5635	Nacht domain
EH233_RS24685	COG1487	ribonuclease activity
EH233_RS24695	COG0732	type I restriction modification DNA specificity domain
EH233_RS24715	COG0540	Belongs to the ATCase OTCase family
EH233_RS24720	COG2205	protein histidine kinase activity
EH233_RS24730	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EH233_RS24740	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EH233_RS24770	COG0297	glycogen (starch) synthase activity
EH233_RS24780	COG2274	protein secretion by the type I secretion system
EH233_RS24785	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EH233_RS24795	COG2205	protein histidine kinase activity
EH233_RS24800	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EH233_RS24810	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EH233_RS24815	COG1942	4-Oxalocrotonate Tautomerase
EH233_RS24830	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
EH233_RS24835	COG2175	clavaminate synthase activity
EH233_RS24840	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EH233_RS24845	COG0581	inorganic phosphate transmembrane transporter activity
EH233_RS24850	COG0573	inorganic phosphate transmembrane transporter activity
EH233_RS24865	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EH233_RS24890	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EH233_RS24895	COG0601	transmembrane transport
EH233_RS24905	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EH233_RS24915	COG0811	peptide transport
EH233_RS24930	COG0616	signal peptide processing
EH233_RS24935	COG1304	FMN binding
EH233_RS24985	COG4974	Belongs to the 'phage' integrase family
EH233_RS25015	COG1475	DNA binding
EH233_RS25020	COG1192	Involved in chromosome partitioning
EH233_RS25035	COG1404	Belongs to the peptidase S8 family
EH233_RS25035	COG4935	Belongs to the peptidase S8 family
EH233_RS25045	COG0590	tRNA wobble adenosine to inosine editing
EH233_RS25050	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EH233_RS25055	COG0702	epimerase
EH233_RS25100	COG1007	ATP synthesis coupled electron transport
EH233_RS25120	COG1982	Orn Lys Arg decarboxylase major
EH233_RS25130	COG1494	fructose-1,6-bisphosphatase
EH233_RS25135	COG0432	Pfam Uncharacterised protein family UPF0047
EH233_RS25140	COG0436	Aminotransferase
EH233_RS25150	COG1615	UPF0182 protein
EH233_RS25200	COG0285	dihydrofolate synthase activity
EH233_RS25225	COG0612	Peptidase, M16
EH233_RS25235	COG0024	Methionine aminopeptidase
EH233_RS25245	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EH233_RS25280	COG2197	response regulator
EH233_RS25285	COG2205	protein histidine kinase activity
EH233_RS25385	COG0463	Glycosyl transferase, family 2
EH233_RS25390	COG1063	alcohol dehydrogenase
EH233_RS25395	COG2831	hemolysin activation secretion protein
EH233_RS25415	COG3210	domain, Protein
EH233_RS25425	COG0436	Aminotransferase
EH233_RS25450	COG0697	spore germination
EH233_RS25460	COG0436	Aminotransferase
EH233_RS25465	COG3118	belongs to the thioredoxin family
EH233_RS25470	COG1842	Phage shock protein A
EH233_RS25475	COG1842	Phage shock protein A
EH233_RS25510	COG0572	uridine kinase
EH233_RS25525	COG2003	Belongs to the UPF0758 family
EH233_RS25545	COG0686	Belongs to the AlaDH PNT family
EH233_RS25550	COG3639	organic phosphonate transmembrane transporter activity
EH233_RS25570	COG0406	alpha-ribazole phosphatase activity
EH233_RS25585	COG3659	wide pore channel activity
EH233_RS25590	COG1172	Belongs to the binding-protein-dependent transport system permease family
EH233_RS25595	COG1129	ABC transporter
EH233_RS25600	COG1879	ABC-type sugar transport system periplasmic component
EH233_RS25605	COG1609	Transcriptional regulator
EH233_RS25610	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EH233_RS25620	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
EH233_RS25630	COG0288	reversible hydration of carbon dioxide
EH233_RS25645	COG0038	chloride channel
EH233_RS25650	COG2154	pterin-4-alpha-carbinolamine dehydratase
EH233_RS25655	COG3659	wide pore channel activity
EH233_RS25660	COG1959	2 iron, 2 sulfur cluster binding
EH233_RS25665	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EH233_RS25670	COG0484	heat shock protein binding
EH233_RS25695	COG2081	HI0933 family
EH233_RS25715	COG2442	InterPro IPR007367
EH233_RS25745	COG0191	fructose-bisphosphate aldolase activity
EH233_RS25750	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EH233_RS25760	COG1979	alcohol dehydrogenase
EH233_RS25765	COG1309	transcriptional regulator
EH233_RS25775	COG0521	Mo-molybdopterin cofactor biosynthetic process
EH233_RS25780	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EH233_RS25785	COG0271	Belongs to the BolA IbaG family
EH233_RS25790	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EH233_RS25800	COG4095	Psort location CytoplasmicMembrane, score
EH233_RS25805	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EH233_RS25830	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EH233_RS25830	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EH233_RS25855	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EH233_RS25860	COG1216	Glycosyl transferase, family 2
EH233_RS25860	COG0463	Glycosyl transferase, family 2
EH233_RS25865	COG2244	polysaccharide biosynthetic process
EH233_RS25870	COG1215	transferase activity, transferring glycosyl groups
EH233_RS25875	COG1215	transferase activity, transferring glycosyl groups
EH233_RS25880	COG0438	transferase activity, transferring glycosyl groups
EH233_RS25890	COG0463	Glycosyl transferase, family 2
EH233_RS25890	COG1216	Glycosyl transferase, family 2
EH233_RS25895	COG5039	Polysaccharide pyruvyl transferase
EH233_RS25900	COG2244	polysaccharide biosynthetic process
EH233_RS25905	COG0438	transferase activity, transferring glycosyl groups
EH233_RS25910	COG0463	Glycosyl transferase, family 2
EH233_RS25910	COG1216	Glycosyl transferase, family 2
EH233_RS25915	COG1216	Glycosyl transferase, family 2
EH233_RS25915	COG0463	Glycosyl transferase, family 2
EH233_RS25920	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
EH233_RS25935	COG0438	transferase activity, transferring glycosyl groups
EH233_RS25940	COG0438	transferase activity, transferring glycosyl groups
EH233_RS25950	COG0515	serine threonine protein kinase
EH233_RS25950	COG2815	serine threonine protein kinase
EH233_RS25965	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EH233_RS25990	COG0076	glutamate decarboxylase activity
EH233_RS26015	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EH233_RS26020	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EH233_RS26025	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EH233_RS26030	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EH233_RS26030	COG1116	anion transmembrane transporter activity
EH233_RS26035	COG1116	anion transmembrane transporter activity
EH233_RS26050	COG2205	protein histidine kinase activity
EH233_RS26060	COG4251	negative regulation of phosphorylation
EH233_RS26065	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
EH233_RS26080	COG0129	dihydroxy-acid dehydratase activity
EH233_RS26185	COG2205	protein histidine kinase activity
EH233_RS26185	COG0784	Response regulator, receiver
EH233_RS26185	COG5002	protein histidine kinase activity
EH233_RS26210	COG0583	DNA-binding transcription factor activity
EH233_RS26225	COG1252	NADH dehydrogenase
EH233_RS26245	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EH233_RS26255	COG0606	chelatase, subunit chli
EH233_RS26260	COG0537	adenosine 5'-monophosphoramidase activity
EH233_RS26270	COG1515	deoxyribonuclease V activity
EH233_RS26290	COG0438	transferase activity, transferring glycosyl groups
EH233_RS26310	COG0426	domain, Protein
EH233_RS26310	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EH233_RS26320	COG0426	domain, Protein
EH233_RS26320	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EH233_RS26335	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EH233_RS26340	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
EH233_RS26360	COG0438	transferase activity, transferring glycosyl groups
EH233_RS26385	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EH233_RS26410	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EH233_RS26415	COG0713	ATP synthesis coupled electron transport
EH233_RS26420	COG0839	Belongs to the complex I subunit 6 family
EH233_RS26425	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EH233_RS26430	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EH233_RS26435	COG0372	Belongs to the citrate synthase family
EH233_RS26440	COG2062	phosphohistidine phosphatase, SixA
EH233_RS26450	COG5001	Diguanylate cyclase
EH233_RS26455	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EH233_RS26475	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EH233_RS26520	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EH233_RS26535	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
EH233_RS26545	COG1881	PFAM PEBP family protein
EH233_RS26555	COG2319	Wd-40 repeat
EH233_RS26555	COG4249	Peptidase C14 caspase catalytic subunit p20
EH233_RS26575	COG0357	Ribosomal RNA small subunit methyltransferase G
EH233_RS26580	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EH233_RS26585	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EH233_RS26590	COG0321	lipoyl(octanoyl) transferase activity
EH233_RS26605	COG0765	amino acid transport
EH233_RS26630	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EH233_RS26635	COG0457	Tetratricopeptide repeat
EH233_RS26640	COG2135	peptidase activity
EH233_RS26645	COG0625	glutathione transferase activity
EH233_RS26650	COG1872	DUF167
EH233_RS26665	COG5592	hemerythrin HHE cation binding domain
EH233_RS26675	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EH233_RS26700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EH233_RS26705	COG1120	ATPase activity
EH233_RS26715	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EH233_RS26720	COG1899	peptidyl-lysine modification to peptidyl-hypusine
EH233_RS26735	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
EH233_RS26750	COG1271	oxidase subunit
EH233_RS26755	COG1294	oxidase, subunit
EH233_RS26765	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EH233_RS26775	COG3259	Nickel-dependent hydrogenase
EH233_RS26790	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EH233_RS26790	COG1042	CoA-binding domain protein
EH233_RS26790	COG0045	succinate-CoA ligase (ADP-forming) activity
EH233_RS26800	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EH233_RS26805	COG4221	oxidoreductase activity
EH233_RS26810	COG2226	methyltransferase
EH233_RS26820	COG0745	RESPONSE REGULATOR receiver
EH233_RS26825	COG1657	PFAM Prenyltransferase squalene oxidase
EH233_RS26845	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
EH233_RS26850	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EH233_RS26855	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EH233_RS26890	COG4942	peptidase
EH233_RS26895	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
EH233_RS26895	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
EH233_RS26900	COG1496	oxidoreductase activity
EH233_RS26905	COG0385	Bile acid
EH233_RS26910	COG4399	Belongs to the UPF0754 family
EH233_RS26915	COG2226	methyltransferase
EH233_RS26920	COG2204	response regulator
EH233_RS26945	COG0300	oxidoreductase activity
EH233_RS26965	COG2255	four-way junction helicase activity
EH233_RS26970	COG0107	imidazoleglycerol-phosphate synthase activity
EH233_RS26980	COG2202	Pas domain
EH233_RS26980	COG2205	protein histidine kinase activity
EH233_RS26985	COG0784	Response regulator, receiver
EH233_RS26990	COG4251	negative regulation of phosphorylation
EH233_RS26995	COG1230	cation diffusion facilitator family transporter
EH233_RS27025	COG0151	Belongs to the GarS family
EH233_RS27030	COG5002	protein histidine kinase activity
EH233_RS27035	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EH233_RS27045	COG2166	iron-sulfur cluster assembly
EH233_RS27070	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EH233_RS27070	COG2022	thiamine diphosphate biosynthetic process
EH233_RS27085	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EH233_RS27100	COG0784	Response regulator, receiver
EH233_RS27100	COG2198	Histidine kinase
EH233_RS27100	COG5002	protein histidine kinase activity
EH233_RS27115	COG1181	Belongs to the D-alanine--D-alanine ligase family
EH233_RS27130	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EH233_RS27135	COG1187	pseudouridine synthase activity
EH233_RS27150	COG0515	serine threonine protein kinase
EH233_RS27205	COG1136	(ABC) transporter
EH233_RS27210	COG0501	Belongs to the peptidase M48B family
EH233_RS27255	COG4245	von Willebrand factor, type A
EH233_RS27265	COG4248	protein with protein kinase and helix-hairpin-helix DNA-binding domains
EH233_RS27315	COG0484	heat shock protein binding
EH233_RS27340	COG2319	Wd-40 repeat
EH233_RS27340	COG3903	Transcriptional regulator
EH233_RS27350	COG0450	alkyl hydroperoxide reductase
EH233_RS27355	COG2304	oxidoreductase activity
EH233_RS27370	COG0438	transferase activity, transferring glycosyl groups
EH233_RS27380	COG0205	6-phosphofructokinase activity
EH233_RS27385	COG0167	dihydroorotate dehydrogenase activity
EH233_RS27390	COG1013	pyruvate-flavodoxin oxidoreductase activity
EH233_RS27390	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EH233_RS27390	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EH233_RS27390	COG0674	pyruvate-flavodoxin oxidoreductase activity
EH233_RS27415	COG0741	lytic transglycosylase activity
EH233_RS27460	COG0515	serine threonine protein kinase
EH233_RS27460	COG1357	PFAM Pentapeptide repeats (8 copies)
EH233_RS27465	COG1136	(ABC) transporter
EH233_RS27475	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EH233_RS27510	COG0693	protein deglycase activity
EH233_RS27565	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EH233_RS27585	COG0501	Belongs to the peptidase M48B family
EH233_RS27620	COG0824	Thioesterase
EH233_RS27625	COG0564	pseudouridine synthase activity
EH233_RS27655	COG1120	ATPase activity
EH233_RS27660	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EH233_RS27665	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EH233_RS27695	COG1858	cytochrome C peroxidase
EH233_RS27705	COG1899	peptidyl-lysine modification to peptidyl-hypusine
EH233_RS27715	COG1968	undecaprenyl-diphosphatase activity
EH233_RS27725	COG1555	photosystem II stabilization
EH233_RS27730	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EH233_RS27745	COG4243	Vitamin k epoxide reductase
EH233_RS27750	COG0434	BtpA family
EH233_RS27755	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EH233_RS27760	COG0513	Belongs to the DEAD box helicase family
EH233_RS27775	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EH233_RS27800	COG2319	Wd-40 repeat
EH233_RS27800	COG4249	Peptidase C14 caspase catalytic subunit p20
EH233_RS27820	COG3321	synthase
EH233_RS27820	COG1028	Short-chain dehydrogenase reductase Sdr
EH233_RS27820	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EH233_RS27820	COG0300	oxidoreductase activity
EH233_RS27820	COG0318	PFAM AMP-dependent synthetase and ligase
EH233_RS27840	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EH233_RS27845	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EH233_RS27850	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EH233_RS27855	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EH233_RS27865	COG2010	Cytochrome c
EH233_RS27870	COG0673	inositol 2-dehydrogenase activity
EH233_RS27885	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EH233_RS27895	COG1228	amidohydrolase
EH233_RS27905	COG0233	cytoplasmic translational termination
EH233_RS27910	COG0528	UMP kinase activity
EH233_RS27945	COG0424	maF-like protein
EH233_RS27965	COG5634	Uncharacterized conserved protein (DUF2278)
EH233_RS27970	COG0242	peptide deformylase activity
EH233_RS27980	COG5001	Diguanylate cyclase
EH233_RS27980	COG4251	negative regulation of phosphorylation
EH233_RS27980	COG3706	GGDEF domain
EH233_RS27980	COG2203	Gaf domain
EH233_RS27990	COG0456	acetyltransferase
EH233_RS27995	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EH233_RS27995	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
EH233_RS28000	COG0583	DNA-binding transcription factor activity
EH233_RS28005	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EH233_RS28020	COG0784	Response regulator, receiver
EH233_RS28030	COG1132	(ABC) transporter
EH233_RS28060	COG0752	glycyl-tRNA synthetase alpha subunit
EH233_RS28070	COG1253	flavin adenine dinucleotide binding
EH233_RS28075	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EH233_RS28080	COG0673	inositol 2-dehydrogenase activity
EH233_RS28085	COG0586	Pfam SNARE associated Golgi protein
EH233_RS28100	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EH233_RS28105	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EH233_RS28160	COG1429	ligase activity, forming nitrogen-metal bonds
EH233_RS28165	COG0515	serine threonine protein kinase
EH233_RS28165	COG3266	domain, Protein
EH233_RS28175	COG0515	serine threonine protein kinase
EH233_RS28175	COG3266	domain, Protein
EH233_RS28190	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
EH233_RS28195	COG0589	response to stress
EH233_RS28195	COG0475	glutathione-regulated potassium exporter activity
EH233_RS28200	COG1234	tRNA 3'-trailer cleavage
EH233_RS28205	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
EH233_RS28210	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EH233_RS28245	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EH233_RS28250	COG5398	heme oxygenase
EH233_RS28255	COG0459	protein refolding
EH233_RS28260	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EH233_RS28265	COG1028	Short-chain dehydrogenase reductase Sdr
EH233_RS28270	COG3118	belongs to the thioredoxin family
EH233_RS28285	COG2264	protein methyltransferase activity
EH233_RS28290	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EH233_RS28295	COG2197	response regulator
EH233_RS28340	COG1845	cytochrome c oxidase, subunit III
EH233_RS28350	COG0306	phosphate transporter
EH233_RS28355	COG2226	methyltransferase
EH233_RS28375	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EH233_RS28375	COG0758	DNA mediated transformation
EH233_RS28385	COG0358	DNA primase activity
EH233_RS28390	COG1446	asparaginase
EH233_RS28420	COG1649	PFAM Uncharacterised BCR, COG1649
EH233_RS28430	COG4249	Peptidase C14 caspase catalytic subunit p20
EH233_RS28455	COG2319	Wd-40 repeat
EH233_RS28455	COG1672	PFAM Archaeal ATPase
EH233_RS28470	COG0438	transferase activity, transferring glycosyl groups
EH233_RS28480	COG0343	queuine tRNA-ribosyltransferase activity
EH233_RS28515	COG0470	DNA polymerase III
EH233_RS28530	COG3335	DDE superfamily endonuclease
EH233_RS28545	COG0776	regulation of translation
EH233_RS28580	COG2373	Large extracellular alpha-helical protein
EH233_RS28585	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EH233_RS28615	COG1845	cytochrome c oxidase, subunit III
EH233_RS28625	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EH233_RS28670	COG1266	CAAX protease self-immunity
EH233_RS28720	COG0512	Glutamine amidotransferase of anthranilate synthase
EH233_RS28720	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EH233_RS28725	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EH233_RS28730	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EH233_RS28755	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EH233_RS28760	COG3903	Transcriptional regulator
EH233_RS28760	COG2319	Wd-40 repeat
EH233_RS28770	COG0798	PFAM Bile acid sodium symporter
EH233_RS28775	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EH233_RS28785	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
EH233_RS28790	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EH233_RS28795	COG0166	Belongs to the GPI family
EH233_RS28840	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EH233_RS28850	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EH233_RS28860	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EH233_RS28860	COG0426	domain, Protein
EH233_RS28865	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EH233_RS28865	COG0426	domain, Protein
EH233_RS28905	COG4948	Mandelate Racemase Muconate Lactonizing
EH233_RS28915	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EH233_RS28945	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EH233_RS28945	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EH233_RS28975	COG0587	DNA-directed DNA polymerase activity
EH233_RS28990	COG1121	(ABC) transporter
EH233_RS29020	COG5635	Nacht domain
EH233_RS29020	COG2319	Wd-40 repeat
EH233_RS29045	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EH233_RS29055	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
EH233_RS29095	COG0640	Transcriptional regulator
EH233_RS29110	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EH233_RS29140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EH233_RS29170	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EH233_RS29175	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EH233_RS29195	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EH233_RS29205	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
EH233_RS29210	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EH233_RS29245	COG0730	response to heat
EH233_RS29255	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EH233_RS29320	COG3385	transposase activity