locus-tag	class	description
acsn021_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
acsn021_RS00010	COG0592	DNA-directed DNA polymerase activity
acsn021_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
acsn021_RS00025	COG0187	DNA topoisomerase II activity
acsn021_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
acsn021_RS00110	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
acsn021_RS00115	COG0745	RESPONSE REGULATOR receiver
acsn021_RS00120	COG5002	protein histidine kinase activity
acsn021_RS00120	COG3850	Histidine kinase
acsn021_RS00125	COG1132	(ABC) transporter
acsn021_RS00130	COG1132	(ABC) transporter
acsn021_RS00135	COG2357	RelA SpoT domain protein
acsn021_RS00140	COG0539	negative regulation of cytoplasmic translation
acsn021_RS00145	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
acsn021_RS00160	COG1362	aminopeptidase activity
acsn021_RS00165	COG3279	Response regulator of the LytR AlgR family
acsn021_RS00195	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
acsn021_RS00205	COG1609	Transcriptional regulator
acsn021_RS00215	COG0058	SHG alpha-glucan phosphorylase activity
acsn021_RS00225	COG1175	transmembrane transport
acsn021_RS00230	COG3833	ABC-type maltose transport systems, permease component
acsn021_RS00315	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
acsn021_RS00320	COG0537	adenosine 5'-monophosphoramidase activity
acsn021_RS00335	COG0457	Tetratricopeptide repeat
acsn021_RS00335	COG0705	Rhomboid family
acsn021_RS00340	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
acsn021_RS00345	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
acsn021_RS00355	COG1846	Transcriptional regulator
acsn021_RS00365	COG0617	tRNA 3'-terminal CCA addition
acsn021_RS00385	COG4466	Protein conserved in bacteria
acsn021_RS00390	COG1388	LysM domain
acsn021_RS00390	COG0791	NLP P60 protein
acsn021_RS00400	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
acsn021_RS00410	COG1181	Belongs to the D-alanine--D-alanine ligase family
acsn021_RS00415	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
acsn021_RS00435	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
acsn021_RS00440	COG1876	peptidase activity
acsn021_RS00445	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
acsn021_RS00450	COG0058	SHG alpha-glucan phosphorylase activity
acsn021_RS00455	COG0714	Associated with various cellular activities
acsn021_RS00475	COG0584	glycerophosphoryl diester phosphodiesterase
acsn021_RS00495	COG4608	Belongs to the ABC transporter superfamily
acsn021_RS00500	COG0444	Belongs to the ABC transporter superfamily
acsn021_RS00505	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
acsn021_RS00510	COG0601	transmembrane transport
acsn021_RS00515	COG4166	transmembrane transport
acsn021_RS00525	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
acsn021_RS00585	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
acsn021_RS00590	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
acsn021_RS00595	COG0017	Asparaginyl-tRNA synthetase
acsn021_RS00600	COG1595	DNA-templated transcription, initiation
acsn021_RS00610	COG0577	efflux transmembrane transporter activity
acsn021_RS00615	COG1136	(ABC) transporter
acsn021_RS00615	COG0577	efflux transmembrane transporter activity
acsn021_RS00640	COG3279	Response regulator of the LytR AlgR family
acsn021_RS00655	COG0183	Belongs to the thiolase family
acsn021_RS00660	COG4689	acetoacetate decarboxylase
acsn021_RS00665	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
acsn021_RS00680	COG2188	Transcriptional regulator
acsn021_RS00685	COG3708	Transcriptional regulator
acsn021_RS00685	COG2207	Transcriptional regulator
acsn021_RS00695	COG1278	Cold shock
acsn021_RS00705	COG1653	transport
acsn021_RS00710	COG4209	transmembrane transport
acsn021_RS00715	COG0395	ABC-type sugar transport system, permease component
acsn021_RS00725	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
acsn021_RS00740	COG1486	melibiose metabolic process
acsn021_RS00745	COG1609	Transcriptional regulator
acsn021_RS00745	COG2207	Transcriptional regulator
acsn021_RS00750	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
acsn021_RS00780	COG3328	transposase activity
acsn021_RS00805	COG0778	Nitroreductase
acsn021_RS00870	COG3299	homolog of phage Mu protein gp47
acsn021_RS00920	COG4717	serine-type aminopeptidase activity
acsn021_RS00925	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
acsn021_RS00980	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
acsn021_RS00985	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
acsn021_RS00995	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
acsn021_RS01000	COG2088	sporulation resulting in formation of a cellular spore
acsn021_RS01015	COG0193	aminoacyl-tRNA hydrolase activity
acsn021_RS01020	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
acsn021_RS01025	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
acsn021_RS01040	COG0671	phosphoesterase, PA-phosphatase related
acsn021_RS01045	COG4555	ABC transporter
acsn021_RS01050	COG1668	transmembrane transport
acsn021_RS01060	COG2002	toxin-antitoxin pair type II binding
acsn021_RS01065	COG3956	TIGRFAM MazG family protein
acsn021_RS01070	COG0776	regulation of translation
acsn021_RS01075	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
acsn021_RS01100	COG2208	phosphoserine phosphatase activity
acsn021_RS01105	COG0037	tRNA processing
acsn021_RS01110	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
acsn021_RS01115	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
acsn021_RS01120	COG3103	Sh3 type 3 domain protein
acsn021_RS01120	COG0366	Alpha amylase catalytic
acsn021_RS01150	COG0635	Involved in the biosynthesis of porphyrin-containing compound
acsn021_RS01155	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
acsn021_RS01160	COG2176	DNA-directed DNA polymerase activity
acsn021_RS01170	COG2720	vancomycin resistance protein
acsn021_RS01175	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
acsn021_RS01180	COG1522	sequence-specific DNA binding
acsn021_RS01185	COG0436	Aminotransferase
acsn021_RS01200	COG5002	protein histidine kinase activity
acsn021_RS01205	COG0745	RESPONSE REGULATOR receiver
acsn021_RS01210	COG1193	negative regulation of DNA recombination
acsn021_RS01390	COG2207	Transcriptional regulator
acsn021_RS01400	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
acsn021_RS01410	COG0716	FMN binding
acsn021_RS01415	COG0635	Involved in the biosynthesis of porphyrin-containing compound
acsn021_RS01430	COG0640	Transcriptional regulator
acsn021_RS01435	COG2217	Heavy metal translocating P-type atpase
acsn021_RS01440	COG0745	RESPONSE REGULATOR receiver
acsn021_RS01445	COG5002	protein histidine kinase activity
acsn021_RS01465	COG1193	negative regulation of DNA recombination
acsn021_RS01475	COG2382	esterase
acsn021_RS01475	COG3693	PFAM glycoside hydrolase, family 10
acsn021_RS01475	COG3507	Belongs to the glycosyl hydrolase 43 family
acsn021_RS01485	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
acsn021_RS01490	COG5520	Belongs to the glycosyl hydrolase 30 family
acsn021_RS01495	COG2508	Transcriptional regulator
acsn021_RS01505	COG1028	Short-chain dehydrogenase reductase Sdr
acsn021_RS01530	COG4555	ABC transporter
acsn021_RS01595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
acsn021_RS01595	COG0723	plastoquinol--plastocyanin reductase activity
acsn021_RS01620	COG3546	catalase activity
acsn021_RS01635	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
acsn021_RS01650	COG3848	Pyruvate phosphate dikinase
acsn021_RS01650	COG0574	Belongs to the PEP-utilizing enzyme family
acsn021_RS01665	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
acsn021_RS01670	COG0860	N-Acetylmuramoyl-L-alanine amidase
acsn021_RS01675	COG1342	Belongs to the UPF0251 family
acsn021_RS01685	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
acsn021_RS01695	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
acsn021_RS01700	COG1280	lysine exporter protein (LysE YggA)
acsn021_RS01705	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
acsn021_RS01710	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
acsn021_RS01720	COG4260	virion core protein, lumpy skin disease virus
acsn021_RS01730	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
acsn021_RS01735	COG1842	Phage shock protein A
acsn021_RS01745	COG1609	Transcriptional regulator
acsn021_RS01750	COG0116	Belongs to the methyltransferase superfamily
acsn021_RS01750	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
acsn021_RS01755	COG0051	transcription antitermination factor activity, RNA binding
acsn021_RS01760	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
acsn021_RS01765	COG0088	Forms part of the polypeptide exit tunnel
acsn021_RS01770	COG0089	rRNA binding
acsn021_RS01775	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
acsn021_RS01780	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
acsn021_RS01785	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
acsn021_RS01790	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
acsn021_RS01795	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
acsn021_RS01800	COG0255	Belongs to the universal ribosomal protein uL29 family
acsn021_RS01805	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
acsn021_RS01810	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
acsn021_RS01815	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
acsn021_RS01820	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
acsn021_RS01825	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
acsn021_RS01830	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
acsn021_RS01835	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
acsn021_RS01840	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
acsn021_RS01845	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
acsn021_RS01850	COG1841	ribosomal large subunit assembly
acsn021_RS01855	COG0200	Binds to the 23S rRNA
acsn021_RS01860	COG0201	protein transport
acsn021_RS01880	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
acsn021_RS01885	COG0257	Belongs to the bacterial ribosomal protein bL36 family
acsn021_RS01890	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
acsn021_RS01895	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
acsn021_RS01900	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
acsn021_RS01905	COG0202	RNA polymerase activity
acsn021_RS01910	COG0203	ribosomal protein L17
acsn021_RS01915	COG2207	Transcriptional regulator
acsn021_RS01920	COG2190	(PTS) system
acsn021_RS01920	COG1263	PTS System
acsn021_RS01920	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
acsn021_RS01930	COG1122	ATPase activity
acsn021_RS01935	COG1122	ATPase activity
acsn021_RS01940	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
acsn021_RS01950	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
acsn021_RS01955	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
acsn021_RS02010	COG4974	Belongs to the 'phage' integrase family
acsn021_RS02060	COG5484	DNA packaging
acsn021_RS02060	COG3728	DNA packaging
acsn021_RS02130	COG2378	regulation of single-species biofilm formation
acsn021_RS02155	COG2382	esterase
acsn021_RS02155	COG3507	Belongs to the glycosyl hydrolase 43 family
acsn021_RS02155	COG3693	PFAM glycoside hydrolase, family 10
acsn021_RS02160	COG3344	reverse transcriptase
acsn021_RS02165	COG3853	Toxic anion resistance protein (TelA)
acsn021_RS02175	COG1609	Transcriptional regulator
acsn021_RS02185	COG4209	transmembrane transport
acsn021_RS02190	COG0395	ABC-type sugar transport system, permease component
acsn021_RS02195	COG1501	Belongs to the glycosyl hydrolase 31 family
acsn021_RS02200	COG0366	Alpha amylase catalytic
acsn021_RS02210	COG1595	DNA-templated transcription, initiation
acsn021_RS02240	COG0534	Mate efflux family protein
acsn021_RS02250	COG1028	Short-chain dehydrogenase reductase Sdr
acsn021_RS02255	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
acsn021_RS02260	COG3842	ATPase activity
acsn021_RS02265	COG2508	Transcriptional regulator
acsn021_RS02270	COG2884	Cell division ATP-binding protein ftsE
acsn021_RS02275	COG2177	Part of the ABC transporter FtsEX involved in
acsn021_RS02280	COG1196	nuclear chromosome segregation
acsn021_RS02280	COG0741	lytic transglycosylase activity
acsn021_RS02280	COG0739	heme binding
acsn021_RS02285	COG0793	Belongs to the peptidase S41A family
acsn021_RS02300	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
acsn021_RS02350	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
acsn021_RS02375	COG3843	relaxase mobilization nuclease domain protein
acsn021_RS02390	COG0514	ATP-dependent DNA helicase (RecQ)
acsn021_RS02420	COG1819	glycosyl
acsn021_RS02430	COG3711	transcriptional antiterminator
acsn021_RS02435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
acsn021_RS02435	COG1263	PTS System
acsn021_RS02435	COG2190	(PTS) system
acsn021_RS02440	COG2723	6-phospho-beta-galactosidase activity
acsn021_RS02455	COG2205	protein histidine kinase activity
acsn021_RS02470	COG1879	ABC-type sugar transport system periplasmic component
acsn021_RS02480	COG1349	DNA-binding transcription factor activity
acsn021_RS02490	COG0813	purine-nucleoside phosphorylase activity
acsn021_RS02495	COG1744	ABC transporter substrate-binding protein PnrA-like
acsn021_RS02500	COG3845	ABC transporter
acsn021_RS02505	COG4603	Belongs to the binding-protein-dependent transport system permease family
acsn021_RS02510	COG1079	Belongs to the binding-protein-dependent transport system permease family
acsn021_RS02515	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
acsn021_RS02520	COG0187	DNA topoisomerase II activity
acsn021_RS02550	COG1256	bacterial-type flagellum assembly
acsn021_RS02550	COG4786	Flagellar basal body rod
acsn021_RS02555	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
acsn021_RS02560	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
acsn021_RS02565	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
acsn021_RS02570	COG1334	flagellar protein FlaG
acsn021_RS02575	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
acsn021_RS02580	COG1516	flagellar protein fliS
acsn021_RS02590	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
acsn021_RS02610	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
acsn021_RS02620	COG0457	Tetratricopeptide repeat
acsn021_RS02620	COG0463	Glycosyl transferase, family 2
acsn021_RS02635	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
acsn021_RS02665	COG1216	Glycosyl transferase, family 2
acsn021_RS02695	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
acsn021_RS02700	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
acsn021_RS02705	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
acsn021_RS02720	COG0463	Glycosyl transferase, family 2
acsn021_RS02720	COG0457	Tetratricopeptide repeat
acsn021_RS02725	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
acsn021_RS02735	COG0504	CTP synthase activity
acsn021_RS02740	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
acsn021_RS02745	COG0322	excinuclease ABC activity
acsn021_RS02750	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
acsn021_RS02755	COG1940	carbohydrate kinase activity
acsn021_RS02760	COG0812	UDP-N-acetylmuramate dehydrogenase activity
acsn021_RS02765	COG1660	Displays ATPase and GTPase activities
acsn021_RS02770	COG1481	regulation of sporulation
acsn021_RS02775	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
acsn021_RS02820	COG1950	PFAM Membrane protein of
acsn021_RS02835	COG1132	(ABC) transporter
acsn021_RS02840	COG0561	phosphatase activity
acsn021_RS02845	COG1595	DNA-templated transcription, initiation
acsn021_RS02865	COG1489	DNA binding
acsn021_RS02875	COG0438	transferase activity, transferring glycosyl groups
acsn021_RS02890	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
acsn021_RS02905	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
acsn021_RS02910	COG1970	mechanosensitive ion channel activity
acsn021_RS02915	COG1376	ErfK ybiS ycfS ynhG family protein
acsn021_RS02935	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
acsn021_RS02975	COG4209	transmembrane transport
acsn021_RS02980	COG0395	ABC-type sugar transport system, permease component
acsn021_RS02985	COG0745	RESPONSE REGULATOR receiver
acsn021_RS03010	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
acsn021_RS03015	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
acsn021_RS03020	COG1160	GTP binding
acsn021_RS03025	COG1027	Aspartate ammonia-lyase
acsn021_RS03215	COG3764	Sortase (surface protein transpeptidase)
acsn021_RS03250	COG0242	peptide deformylase activity
acsn021_RS03460	COG0352	thiamine-phosphate diphosphorylase activity
acsn021_RS03465	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
acsn021_RS03470	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
acsn021_RS03475	COG0352	thiamine-phosphate diphosphorylase activity
acsn021_RS03475	COG0351	phosphomethylpyrimidine kinase
acsn021_RS03485	COG1653	transport
acsn021_RS03490	COG1175	transmembrane transport
acsn021_RS03495	COG0395	ABC-type sugar transport system, permease component
acsn021_RS03500	COG0745	RESPONSE REGULATOR receiver
acsn021_RS03505	COG2205	protein histidine kinase activity
acsn021_RS03510	COG0306	phosphate transporter
acsn021_RS03520	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
acsn021_RS03525	COG0569	domain protein
acsn021_RS03540	COG0714	Associated with various cellular activities
acsn021_RS03555	COG0628	permease
acsn021_RS03560	COG1136	(ABC) transporter
acsn021_RS03575	COG0577	efflux transmembrane transporter activity
acsn021_RS03610	COG0667	Aldo Keto reductase
acsn021_RS03615	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
acsn021_RS03620	COG0210	DNA helicase
acsn021_RS03625	COG3906	Belongs to the UPF0473 family
acsn021_RS03645	COG1597	lipid kinase activity
acsn021_RS03665	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
acsn021_RS03675	COG1381	Involved in DNA repair and RecF pathway recombination
acsn021_RS03685	COG0423	glycine-tRNA ligase activity
acsn021_RS03690	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
acsn021_RS03690	COG0574	Belongs to the PEP-utilizing enzyme family
acsn021_RS03700	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
acsn021_RS03705	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
acsn021_RS03705	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
acsn021_RS03735	COG1396	sequence-specific DNA binding
acsn021_RS03755	COG0395	ABC-type sugar transport system, permease component
acsn021_RS03780	COG0395	ABC-type sugar transport system, permease component
acsn021_RS03800	COG4753	response regulator
acsn021_RS03800	COG2207	Transcriptional regulator
acsn021_RS03830	COG1316	TRANSCRIPTIONal
acsn021_RS03840	COG0726	polysaccharide deacetylase
acsn021_RS03890	COG1136	(ABC) transporter
acsn021_RS03905	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
acsn021_RS03910	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
acsn021_RS03925	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
acsn021_RS03965	COG1132	(ABC) transporter
acsn021_RS03965	COG2375	cellular response to nickel ion
acsn021_RS03970	COG1132	(ABC) transporter
acsn021_RS03980	COG4753	response regulator
acsn021_RS03980	COG2207	Transcriptional regulator
acsn021_RS04000	COG1959	2 iron, 2 sulfur cluster binding
acsn021_RS04010	COG4977	sequence-specific DNA binding
acsn021_RS04030	COG1874	Beta-galactosidase
acsn021_RS04035	COG1733	regulation of RNA biosynthetic process
acsn021_RS04045	COG2207	Transcriptional regulator
acsn021_RS04045	COG1609	Transcriptional regulator
acsn021_RS04155	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
acsn021_RS04165	COG1447	Phosphotransferase system cellobiose-specific component IIA
acsn021_RS04175	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
acsn021_RS04180	COG3250	beta-galactosidase activity
acsn021_RS04185	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
acsn021_RS04185	COG3711	transcriptional antiterminator
acsn021_RS04190	COG3275	phosphorelay sensor kinase activity
acsn021_RS04195	COG4209	transmembrane transport
acsn021_RS04200	COG0395	ABC-type sugar transport system, permease component
acsn021_RS04210	COG4753	response regulator
acsn021_RS04210	COG2207	Transcriptional regulator
acsn021_RS04230	COG1028	Short-chain dehydrogenase reductase Sdr
acsn021_RS04240	COG0840	transmembrane signaling receptor activity
acsn021_RS04245	COG0473	3-isopropylmalate dehydrogenase activity
acsn021_RS04245	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
acsn021_RS04255	COG2721	sulfolactate sulfo-lyase activity
acsn021_RS04260	COG1028	Short-chain dehydrogenase reductase Sdr
acsn021_RS04270	COG3870	Protein conserved in bacteria
acsn021_RS04280	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
acsn021_RS04285	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
acsn021_RS04290	COG0784	Response regulator, receiver
acsn021_RS04290	COG3437	response regulator, receiver
acsn021_RS04295	COG2195	Cleaves the N-terminal amino acid of tripeptides
acsn021_RS04300	COG1522	sequence-specific DNA binding
acsn021_RS04305	COG1027	Aspartate ammonia-lyase
acsn021_RS04310	COG0586	Pfam SNARE associated Golgi protein
acsn021_RS04330	COG4124	Belongs to the glycosyl hydrolase 26 family
acsn021_RS04335	COG0534	Mate efflux family protein
acsn021_RS04365	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
acsn021_RS04400	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
acsn021_RS04410	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
acsn021_RS04415	COG1028	Short-chain dehydrogenase reductase Sdr
acsn021_RS04425	COG3254	rhamnose metabolic process
acsn021_RS04435	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
acsn021_RS04440	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
acsn021_RS04455	COG0534	Mate efflux family protein
acsn021_RS04470	COG3773	Cell wall hydrolase
acsn021_RS04475	COG0488	(ABC) transporter
acsn021_RS04495	COG1979	alcohol dehydrogenase
acsn021_RS04505	COG2873	o-acetylhomoserine
acsn021_RS04510	COG1959	2 iron, 2 sulfur cluster binding
acsn021_RS04515	COG1073	alpha beta
acsn021_RS04525	COG0295	cytidine deaminase activity
acsn021_RS04545	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
acsn021_RS04555	COG1045	serine acetyltransferase
acsn021_RS04560	COG0215	cysteine-tRNA ligase activity
acsn021_RS04570	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
acsn021_RS04630	COG3576	pyridoxamine 5-phosphate
acsn021_RS04655	COG0232	Belongs to the dGTPase family. Type 2 subfamily
acsn021_RS04660	COG0358	DNA primase activity
acsn021_RS04665	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
acsn021_RS04670	COG2384	SAM-dependent methyltransferase
acsn021_RS04675	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
acsn021_RS04720	COG1131	(ABC) transporter
acsn021_RS04735	COG3773	Cell wall hydrolase
acsn021_RS04740	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
acsn021_RS04750	COG1216	Glycosyl transferase, family 2
acsn021_RS04780	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
acsn021_RS04785	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
acsn021_RS04795	COG1216	Glycosyl transferase, family 2
acsn021_RS04815	COG1682	transport, permease protein
acsn021_RS04825	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
acsn021_RS04830	COG0438	transferase activity, transferring glycosyl groups
acsn021_RS04830	COG1216	Glycosyl transferase, family 2
acsn021_RS04835	COG0438	transferase activity, transferring glycosyl groups
acsn021_RS04845	COG1696	Membrane protein involved in D-alanine export
acsn021_RS04885	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
acsn021_RS04890	COG0662	Cupin 2, conserved barrel domain protein
acsn021_RS04890	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
acsn021_RS04895	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
acsn021_RS04910	COG0628	permease
acsn021_RS04945	COG0438	transferase activity, transferring glycosyl groups
acsn021_RS04995	COG0765	amino acid transport
acsn021_RS05000	COG0765	amino acid transport
acsn021_RS05005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
acsn021_RS05010	COG1126	abc transporter atp-binding protein
acsn021_RS05030	COG1691	(AIR) carboxylase
acsn021_RS05035	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
acsn021_RS05045	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
acsn021_RS05050	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
acsn021_RS05055	COG1116	anion transmembrane transporter activity
acsn021_RS05075	COG1217	gtp-binding protein TYPA
acsn021_RS05090	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
acsn021_RS05095	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
acsn021_RS05105	COG1396	sequence-specific DNA binding
acsn021_RS05140	COG0840	transmembrane signaling receptor activity
acsn021_RS05145	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
acsn021_RS05150	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
acsn021_RS05150	COG0072	phenylalanine-tRNA ligase activity
acsn021_RS05175	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
acsn021_RS05185	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
acsn021_RS05190	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
acsn021_RS05195	COG0151	Belongs to the GarS family
acsn021_RS05215	COG3880	PFAM UvrB UvrC protein
acsn021_RS05220	COG3869	Catalyzes the specific phosphorylation of arginine residues in
acsn021_RS05225	COG0542	response to heat
acsn021_RS05235	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
acsn021_RS05300	COG0714	Associated with various cellular activities
acsn021_RS05305	COG0343	queuine tRNA-ribosyltransferase activity
acsn021_RS05310	COG1862	Preprotein translocase
acsn021_RS05315	COG0613	PHP domain protein
acsn021_RS05330	COG0820	rRNA (adenine-C2-)-methyltransferase activity
acsn021_RS05335	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
acsn021_RS05335	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
acsn021_RS05340	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
acsn021_RS05340	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
acsn021_RS05345	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
acsn021_RS05350	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
acsn021_RS05355	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
acsn021_RS05360	COG0635	Involved in the biosynthesis of porphyrin-containing compound
acsn021_RS05370	COG0124	histidyl-tRNA synthetase
acsn021_RS05380	COG1362	aminopeptidase activity
acsn021_RS05390	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
acsn021_RS05400	COG3326	Membrane
acsn021_RS05405	COG1396	sequence-specific DNA binding
acsn021_RS05435	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
acsn021_RS05455	COG1162	GTPase activity
acsn021_RS05480	COG0531	amino acid
acsn021_RS05485	COG2226	methyltransferase
acsn021_RS05495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
acsn021_RS05500	COG1192	Involved in chromosome partitioning
acsn021_RS05505	COG1475	DNA binding
acsn021_RS05710	COG2003	Belongs to the UPF0758 family
acsn021_RS05745	COG0270	DNA (cytosine-5-)-methyltransferase activity
acsn021_RS05860	COG1598	PFAM Uncharacterised protein family UPF0150
acsn021_RS05880	COG3328	transposase activity
acsn021_RS05930	COG1396	sequence-specific DNA binding
acsn021_RS05945	COG0726	polysaccharide deacetylase
acsn021_RS05965	COG1228	amidohydrolase
acsn021_RS05970	COG3279	Response regulator of the LytR AlgR family
acsn021_RS05980	COG3706	GGDEF domain
acsn021_RS05985	COG1396	sequence-specific DNA binding
acsn021_RS05990	COG1396	sequence-specific DNA binding
acsn021_RS05995	COG1528	Iron-storage protein
acsn021_RS06010	COG4120	Belongs to the binding-protein-dependent transport system permease family
acsn021_RS06015	COG1116	anion transmembrane transporter activity
acsn021_RS06040	COG0436	Aminotransferase
acsn021_RS06055	COG0017	Asparaginyl-tRNA synthetase
acsn021_RS06060	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
acsn021_RS06065	COG0154	amidase activity
acsn021_RS06070	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
acsn021_RS06085	COG0067	glutamate synthase
acsn021_RS06085	COG0070	glutamate synthase
acsn021_RS06085	COG0069	glutamate synthase activity
acsn021_RS06090	COG0493	'glutamate synthase
acsn021_RS06095	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
acsn021_RS06130	COG0551	DNA topoisomerase type I activity
acsn021_RS06130	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
acsn021_RS06140	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
acsn021_RS06160	COG4209	transmembrane transport
acsn021_RS06165	COG0395	ABC-type sugar transport system, permease component
acsn021_RS06180	COG1956	GAF domain-containing protein
acsn021_RS06190	COG1773	rubredoxin
acsn021_RS06195	COG0840	transmembrane signaling receptor activity
acsn021_RS06205	COG2205	protein histidine kinase activity
acsn021_RS06210	COG0745	RESPONSE REGULATOR receiver
acsn021_RS06250	COG0124	histidyl-tRNA synthetase
acsn021_RS06265	COG1959	2 iron, 2 sulfur cluster binding
acsn021_RS06300	COG2205	protein histidine kinase activity
acsn021_RS06320	COG1331	Highly conserved protein containing a thioredoxin domain
acsn021_RS06325	COG2094	Belongs to the DNA glycosylase MPG family
acsn021_RS06355	COG0384	phenazine biosynthesis protein PhzF
acsn021_RS06370	COG0789	Transcriptional regulator
acsn021_RS06385	COG2378	regulation of single-species biofilm formation
acsn021_RS06390	COG3340	Belongs to the peptidase S51 family
acsn021_RS06415	COG0646	methionine synthase
acsn021_RS06415	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
acsn021_RS06425	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
acsn021_RS06430	COG0646	methionine synthase
acsn021_RS06430	COG1410	methionine synthase
acsn021_RS06435	COG1846	Transcriptional regulator
acsn021_RS06445	COG1132	(ABC) transporter
acsn021_RS06455	COG2059	Chromate
acsn021_RS06465	COG0583	DNA-binding transcription factor activity
acsn021_RS06470	COG0789	Transcriptional regulator
acsn021_RS06475	COG0561	phosphatase activity
acsn021_RS06480	COG0534	Mate efflux family protein
acsn021_RS06520	COG1132	(ABC) transporter
acsn021_RS06560	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
acsn021_RS06590	COG1136	(ABC) transporter
acsn021_RS06590	COG0577	efflux transmembrane transporter activity
acsn021_RS06630	COG0535	radical SAM domain protein
acsn021_RS06645	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
acsn021_RS06670	COG4496	protein, YerC YecD
acsn021_RS06675	COG1053	succinate dehydrogenase
acsn021_RS06675	COG0431	NADPH-dependent FMN reductase
acsn021_RS06675	COG3976	FMN-binding domain protein
acsn021_RS06680	COG0656	L-ascorbic acid biosynthetic process
acsn021_RS06695	COG1131	(ABC) transporter
acsn021_RS06700	COG1695	Transcriptional regulator
acsn021_RS06705	COG0154	amidase activity
acsn021_RS06710	COG1132	(ABC) transporter
acsn021_RS06715	COG4447	cellulose binding
acsn021_RS06715	COG5297	Belongs to the glycosyl hydrolase family 6
acsn021_RS06725	COG2205	protein histidine kinase activity
acsn021_RS06730	COG0745	RESPONSE REGULATOR receiver
acsn021_RS06740	COG0640	Transcriptional regulator
acsn021_RS06750	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
acsn021_RS06820	COG0534	Mate efflux family protein
acsn021_RS06825	COG4977	sequence-specific DNA binding
acsn021_RS06835	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
acsn021_RS06840	COG0444	Belongs to the ABC transporter superfamily
acsn021_RS06855	COG2375	cellular response to nickel ion
acsn021_RS06855	COG1132	(ABC) transporter
acsn021_RS06860	COG1132	(ABC) transporter
acsn021_RS06935	COG1573	uracil-dna glycosylase
acsn021_RS06945	COG0366	Alpha amylase catalytic
acsn021_RS06950	COG1846	Transcriptional regulator
acsn021_RS06955	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
acsn021_RS06975	COG1136	(ABC) transporter
acsn021_RS06985	COG0577	efflux transmembrane transporter activity
acsn021_RS06985	COG1136	(ABC) transporter
acsn021_RS06990	COG3850	Histidine kinase
acsn021_RS06990	COG5002	protein histidine kinase activity
acsn021_RS06995	COG0745	RESPONSE REGULATOR receiver
acsn021_RS07000	COG1595	DNA-templated transcription, initiation
acsn021_RS07015	COG3695	enzyme binding
acsn021_RS07030	COG3328	transposase activity
acsn021_RS07035	COG0693	protein deglycase activity
acsn021_RS07040	COG0561	phosphatase activity
acsn021_RS07055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
acsn021_RS07060	COG0601	transmembrane transport
acsn021_RS07080	COG1529	Aldehyde oxidase and xanthine dehydrogenase
acsn021_RS07085	COG0709	Synthesizes selenophosphate from selenide and ATP
acsn021_RS07105	COG3608	succinylglutamate desuccinylase aspartoacylase
acsn021_RS07105	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
acsn021_RS07115	COG1611	Belongs to the LOG family
acsn021_RS07120	COG0583	DNA-binding transcription factor activity
acsn021_RS07150	COG4912	Dna alkylation repair
acsn021_RS07155	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
acsn021_RS07165	COG1131	(ABC) transporter
acsn021_RS07170	COG0789	Transcriptional regulator
acsn021_RS07175	COG4209	transmembrane transport
acsn021_RS07180	COG0395	ABC-type sugar transport system, permease component
acsn021_RS07185	COG1653	transport
acsn021_RS07190	COG1053	succinate dehydrogenase
acsn021_RS07210	COG3459	Glycosyltransferase 36 associated
acsn021_RS07215	COG4753	response regulator
acsn021_RS07215	COG2207	Transcriptional regulator
acsn021_RS07220	COG2972	Histidine kinase
acsn021_RS07250	COG0436	Aminotransferase
acsn021_RS07255	COG2502	aspartate--ammonia ligase
acsn021_RS07270	COG1937	Protein conserved in bacteria
acsn021_RS07280	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
acsn021_RS07285	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
acsn021_RS07290	COG1120	ATPase activity
acsn021_RS07315	COG3620	sequence-specific DNA binding
acsn021_RS07330	COG2132	Multicopper oxidase
acsn021_RS07335	COG1737	Transcriptional regulator
acsn021_RS07340	COG2723	6-phospho-beta-galactosidase activity
acsn021_RS07350	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
acsn021_RS07360	COG0583	DNA-binding transcription factor activity
acsn021_RS07365	COG0604	alcohol dehydrogenase
acsn021_RS07375	COG1404	Belongs to the peptidase S8 family
acsn021_RS07375	COG4412	M6 family metalloprotease domain protein
acsn021_RS07385	COG0375	protein maturation
acsn021_RS07410	COG0110	maltose O-acetyltransferase activity
acsn021_RS07415	COG3226	Transcriptional regulator
acsn021_RS07425	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
acsn021_RS07430	COG0745	RESPONSE REGULATOR receiver
acsn021_RS07435	COG5002	protein histidine kinase activity
acsn021_RS07435	COG3850	Histidine kinase
acsn021_RS07475	COG0561	phosphatase activity
acsn021_RS07480	COG1108	ABC-type Mn2 Zn2 transport systems permease components
acsn021_RS07485	COG1108	ABC-type Mn2 Zn2 transport systems permease components
acsn021_RS07490	COG1121	(ABC) transporter
acsn021_RS07495	COG0803	Belongs to the bacterial solute-binding protein 9 family
acsn021_RS07500	COG3401	FG-GAP repeat protein
acsn021_RS07505	COG0745	RESPONSE REGULATOR receiver
acsn021_RS07510	COG5002	protein histidine kinase activity
acsn021_RS07535	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
acsn021_RS07545	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
acsn021_RS07555	COG1447	Phosphotransferase system cellobiose-specific component IIA
acsn021_RS07560	COG2723	6-phospho-beta-galactosidase activity
acsn021_RS07570	COG4221	oxidoreductase activity
acsn021_RS07600	COG2207	Transcriptional regulator
acsn021_RS07600	COG4753	response regulator
acsn021_RS07605	COG2972	Histidine kinase
acsn021_RS07610	COG1879	ABC-type sugar transport system periplasmic component
acsn021_RS07620	COG1172	Belongs to the binding-protein-dependent transport system permease family
acsn021_RS07625	COG1172	Belongs to the binding-protein-dependent transport system permease family
acsn021_RS07630	COG0488	(ABC) transporter
acsn021_RS07640	COG1376	ErfK ybiS ycfS ynhG family protein
acsn021_RS07645	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
acsn021_RS07655	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
acsn021_RS07660	COG2207	Transcriptional regulator
acsn021_RS07660	COG1917	Cupin 2, conserved barrel domain protein
acsn021_RS07675	COG2207	Transcriptional regulator
acsn021_RS07680	COG4209	transmembrane transport
acsn021_RS07685	COG0395	ABC-type sugar transport system, permease component
acsn021_RS07705	COG3507	Belongs to the glycosyl hydrolase 43 family
acsn021_RS07710	COG2972	Histidine kinase
acsn021_RS07715	COG2207	Transcriptional regulator
acsn021_RS07715	COG4753	response regulator
acsn021_RS07725	COG4209	transmembrane transport
acsn021_RS07730	COG0395	ABC-type sugar transport system, permease component
acsn021_RS07755	COG3279	Response regulator of the LytR AlgR family
acsn021_RS07775	COG2070	2-Nitropropane dioxygenase
acsn021_RS07775	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
acsn021_RS07780	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
acsn021_RS07785	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
acsn021_RS07790	COG3321	synthase
acsn021_RS07790	COG4221	oxidoreductase activity
acsn021_RS07790	COG1028	Short-chain dehydrogenase reductase Sdr
acsn021_RS07790	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
acsn021_RS07795	COG4221	oxidoreductase activity
acsn021_RS07795	COG3321	synthase
acsn021_RS07795	COG1028	Short-chain dehydrogenase reductase Sdr
acsn021_RS07795	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
acsn021_RS07800	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
acsn021_RS07800	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
acsn021_RS07800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
acsn021_RS07800	COG1028	Short-chain dehydrogenase reductase Sdr
acsn021_RS07800	COG3321	synthase
acsn021_RS07805	COG0300	oxidoreductase activity
acsn021_RS07805	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
acsn021_RS07805	COG4221	oxidoreductase activity
acsn021_RS07805	COG3321	synthase
acsn021_RS07810	COG4221	oxidoreductase activity
acsn021_RS07810	COG3321	synthase
acsn021_RS07810	COG1028	Short-chain dehydrogenase reductase Sdr
acsn021_RS07810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
acsn021_RS07815	COG4221	oxidoreductase activity
acsn021_RS07815	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
acsn021_RS07815	COG0300	oxidoreductase activity
acsn021_RS07815	COG3321	synthase
acsn021_RS07820	COG1028	Short-chain dehydrogenase reductase Sdr
acsn021_RS07820	COG4221	oxidoreductase activity
acsn021_RS07820	COG3321	synthase
acsn021_RS07820	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
acsn021_RS07845	COG1024	Enoyl-CoA hydratase
acsn021_RS07850	COG3425	synthase
acsn021_RS07880	COG1136	(ABC) transporter
acsn021_RS07880	COG0577	efflux transmembrane transporter activity
acsn021_RS07885	COG1253	flavin adenine dinucleotide binding
acsn021_RS07905	COG0395	ABC-type sugar transport system, permease component
acsn021_RS07910	COG2972	Histidine kinase
acsn021_RS07930	COG0431	NADPH-dependent FMN reductase
acsn021_RS07930	COG1053	succinate dehydrogenase
acsn021_RS07930	COG3976	FMN-binding domain protein
acsn021_RS07945	COG4977	sequence-specific DNA binding
acsn021_RS07945	COG1917	Cupin 2, conserved barrel domain protein
acsn021_RS07955	COG1653	transport
acsn021_RS07965	COG0395	ABC-type sugar transport system, permease component
acsn021_RS07985	COG1175	transmembrane transport
acsn021_RS07990	COG0395	ABC-type sugar transport system, permease component
acsn021_RS08000	COG3507	Belongs to the glycosyl hydrolase 43 family
acsn021_RS08020	COG1309	transcriptional regulator
acsn021_RS08030	COG0860	N-Acetylmuramoyl-L-alanine amidase
acsn021_RS08040	COG0765	amino acid transport
acsn021_RS08045	COG1126	abc transporter atp-binding protein
acsn021_RS08055	COG3250	beta-galactosidase activity
acsn021_RS08060	COG2723	6-phospho-beta-galactosidase activity
acsn021_RS08065	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
acsn021_RS08070	COG1011	Hydrolase
acsn021_RS08075	COG1201	RNA secondary structure unwinding
acsn021_RS08130	COG3711	transcriptional antiterminator
acsn021_RS08140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
acsn021_RS08140	COG2190	(PTS) system
acsn021_RS08140	COG1263	PTS System
acsn021_RS08145	COG1136	(ABC) transporter
acsn021_RS08145	COG0577	efflux transmembrane transporter activity
acsn021_RS08160	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
acsn021_RS08170	COG1584	GPR1 FUN34 yaaH family protein
acsn021_RS08190	COG0789	Transcriptional regulator
acsn021_RS08200	COG0622	Phosphoesterase
acsn021_RS08210	COG0527	aspartate kinase activity
acsn021_RS08230	COG1874	Beta-galactosidase
acsn021_RS08250	COG0697	spore germination
acsn021_RS08255	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
acsn021_RS08260	COG0428	transporter
acsn021_RS08270	COG0778	Nitroreductase
acsn021_RS08270	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
acsn021_RS08290	COG1132	(ABC) transporter
acsn021_RS08295	COG1120	ATPase activity
acsn021_RS08300	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
acsn021_RS08305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
acsn021_RS08330	COG3620	sequence-specific DNA binding
acsn021_RS08335	COG1132	(ABC) transporter
acsn021_RS08345	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
acsn021_RS08350	COG1971	Probably functions as a manganese efflux pump
acsn021_RS08380	COG1131	(ABC) transporter
acsn021_RS08390	COG3708	Transcriptional regulator
acsn021_RS08390	COG2207	Transcriptional regulator
acsn021_RS08410	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
acsn021_RS08430	COG1674	ftsk spoiiie
acsn021_RS08440	COG2946	Replication initiation factor
acsn021_RS08475	COG0741	lytic transglycosylase activity
acsn021_RS08475	COG0791	NLP P60 protein
acsn021_RS08510	COG1131	(ABC) transporter
acsn021_RS08555	COG0840	transmembrane signaling receptor activity
acsn021_RS08580	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
acsn021_RS08580	COG1605	Chorismate mutase
acsn021_RS08605	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
acsn021_RS08625	COG0436	Aminotransferase
acsn021_RS08655	COG3959	Transketolase, thiamine diphosphate binding domain
acsn021_RS08660	COG3958	Transketolase
acsn021_RS08710	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
acsn021_RS08715	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
acsn021_RS08735	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
acsn021_RS08760	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
acsn021_RS08770	COG0475	glutathione-regulated potassium exporter activity
acsn021_RS08780	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
acsn021_RS08785	COG4716	Myosin-crossreactive antigen
acsn021_RS08795	COG0275	rRNA processing
acsn021_RS08800	COG0513	Belongs to the DEAD box helicase family
acsn021_RS08820	COG0745	RESPONSE REGULATOR receiver
acsn021_RS08820	COG2972	Histidine kinase
acsn021_RS08825	COG3279	Response regulator of the LytR AlgR family
acsn021_RS08835	COG0544	peptidyl-prolyl cis-trans isomerase activity
acsn021_RS08840	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
acsn021_RS08855	COG2382	esterase
acsn021_RS08870	COG4209	transmembrane transport
acsn021_RS08875	COG0395	ABC-type sugar transport system, permease component
acsn021_RS08890	COG3507	Belongs to the glycosyl hydrolase 43 family
acsn021_RS08895	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
acsn021_RS08915	COG5646	InterPro IPR014922
acsn021_RS08925	COG1309	transcriptional regulator
acsn021_RS08935	COG4977	sequence-specific DNA binding
acsn021_RS08945	COG4209	transmembrane transport
acsn021_RS08950	COG0395	ABC-type sugar transport system, permease component
acsn021_RS08960	COG1408	metallophosphoesterase
acsn021_RS08965	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
acsn021_RS08970	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
acsn021_RS08970	COG2207	Transcriptional regulator
acsn021_RS09000	COG3250	beta-galactosidase activity
acsn021_RS09010	COG1312	Catalyzes the dehydration of D-mannonate
acsn021_RS09015	COG1028	Short-chain dehydrogenase reductase Sdr
acsn021_RS09025	COG5002	protein histidine kinase activity
acsn021_RS09030	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
acsn021_RS09055	COG0010	Belongs to the arginase family
acsn021_RS09090	COG4656	Part of a membrane complex involved in electron transport
acsn021_RS09135	COG0840	transmembrane signaling receptor activity
acsn021_RS09150	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
acsn021_RS09155	COG1695	Transcriptional regulator
acsn021_RS09170	COG1268	BioY protein
acsn021_RS09175	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
acsn021_RS09185	COG0572	uridine kinase
acsn021_RS09190	COG2214	Heat shock protein DnaJ domain protein
acsn021_RS09195	COG0443	Heat shock 70 kDa protein
acsn021_RS09210	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
acsn021_RS09215	COG0420	3'-5' exonuclease activity
acsn021_RS09220	COG0419	ATPase involved in DNA repair
acsn021_RS09225	COG0714	Associated with various cellular activities
acsn021_RS09235	COG3552	Protein containing von Willebrand factor type A (VWA) domain
acsn021_RS09250	COG3831	ATPase activity
acsn021_RS09255	COG0747	negative chemotaxis
acsn021_RS09260	COG0601	transmembrane transport
acsn021_RS09265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
acsn021_RS09270	COG0444	Belongs to the ABC transporter superfamily
acsn021_RS09275	COG4608	Belongs to the ABC transporter superfamily
acsn021_RS09310	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
acsn021_RS09315	COG0673	inositol 2-dehydrogenase activity
acsn021_RS09325	COG4977	sequence-specific DNA binding
acsn021_RS09340	COG0277	FAD linked oxidase domain protein
acsn021_RS09345	COG3711	transcriptional antiterminator
acsn021_RS09350	COG1263	PTS System
acsn021_RS09350	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
acsn021_RS09350	COG2190	(PTS) system
acsn021_RS09375	COG5566	PFAM Mor transcription activator
acsn021_RS09405	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
acsn021_RS09425	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
acsn021_RS09440	COG0583	DNA-binding transcription factor activity
acsn021_RS09445	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
acsn021_RS09450	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
acsn021_RS09455	COG0459	protein refolding
acsn021_RS09460	COG0250	Participates in transcription elongation, termination and antitermination
acsn021_RS09495	COG2207	Transcriptional regulator
acsn021_RS09500	COG0457	Tetratricopeptide repeat
acsn021_RS09510	COG0561	phosphatase activity
acsn021_RS09515	COG3711	transcriptional antiterminator
acsn021_RS09520	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
acsn021_RS09520	COG1263	PTS System
acsn021_RS09520	COG2190	(PTS) system
acsn021_RS09525	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
acsn021_RS09535	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
acsn021_RS09560	COG0519	Catalyzes the synthesis of GMP from XMP
acsn021_RS09565	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
acsn021_RS09600	COG1518	maintenance of DNA repeat elements
acsn021_RS09605	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
acsn021_RS09615	COG1486	melibiose metabolic process
acsn021_RS09640	COG3250	beta-galactosidase activity
acsn021_RS09645	COG1917	Cupin 2, conserved barrel domain protein
acsn021_RS09645	COG2207	Transcriptional regulator
acsn021_RS09650	COG1472	Belongs to the glycosyl hydrolase 3 family
acsn021_RS09660	COG4209	transmembrane transport
acsn021_RS09665	COG0395	ABC-type sugar transport system, permease component
acsn021_RS09675	COG1151	hydroxylamine reductase activity
acsn021_RS09680	COG1696	Membrane protein involved in D-alanine export
acsn021_RS09690	COG3279	Response regulator of the LytR AlgR family
acsn021_RS09715	COG1917	Cupin 2, conserved barrel domain protein
acsn021_RS09715	COG2207	Transcriptional regulator
acsn021_RS09720	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
acsn021_RS09735	COG1349	DNA-binding transcription factor activity
acsn021_RS09740	COG1105	Belongs to the carbohydrate kinase PfkB family
acsn021_RS09745	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
acsn021_RS09745	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
acsn021_RS09745	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
acsn021_RS09855	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
acsn021_RS09860	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
acsn021_RS09870	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
acsn021_RS09875	COG1250	3-hydroxyacyl-CoA dehydrogenase
acsn021_RS09875	COG1024	Enoyl-CoA hydratase
acsn021_RS09880	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
acsn021_RS09890	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
acsn021_RS09895	COG1028	Short-chain dehydrogenase reductase Sdr
acsn021_RS09910	COG0300	oxidoreductase activity
acsn021_RS09910	COG3321	synthase
acsn021_RS09910	COG1028	Short-chain dehydrogenase reductase Sdr
acsn021_RS09910	COG0318	PFAM AMP-dependent synthetase and ligase
acsn021_RS09910	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
acsn021_RS09915	COG1028	Short-chain dehydrogenase reductase Sdr
acsn021_RS09915	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
acsn021_RS09915	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
acsn021_RS09915	COG3321	synthase
acsn021_RS09915	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
acsn021_RS09920	COG4221	oxidoreductase activity
acsn021_RS09920	COG3321	synthase
acsn021_RS09920	COG1028	Short-chain dehydrogenase reductase Sdr
acsn021_RS09920	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
acsn021_RS09925	COG4221	oxidoreductase activity
acsn021_RS09925	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
acsn021_RS09925	COG3321	synthase
acsn021_RS09925	COG1028	Short-chain dehydrogenase reductase Sdr
acsn021_RS09930	COG4221	oxidoreductase activity
acsn021_RS09930	COG3321	synthase
acsn021_RS09930	COG0300	oxidoreductase activity
acsn021_RS09930	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
acsn021_RS09930	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
acsn021_RS09930	COG0300	oxidoreductase activity
acsn021_RS09930	COG3321	synthase
acsn021_RS09930	COG4221	oxidoreductase activity
acsn021_RS09935	COG3321	synthase
acsn021_RS09935	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
acsn021_RS09935	COG4221	oxidoreductase activity
acsn021_RS09935	COG0300	oxidoreductase activity
acsn021_RS09945	COG0300	oxidoreductase activity
acsn021_RS09945	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
acsn021_RS09945	COG4221	oxidoreductase activity
acsn021_RS09945	COG3321	synthase
acsn021_RS09945	COG4221	oxidoreductase activity
acsn021_RS09945	COG3321	synthase
acsn021_RS09945	COG0300	oxidoreductase activity
acsn021_RS09945	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
acsn021_RS09965	COG1131	(ABC) transporter
acsn021_RS10020	COG3620	sequence-specific DNA binding
acsn021_RS10060	COG1335	isochorismatase
acsn021_RS10070	COG2226	methyltransferase
acsn021_RS10075	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
acsn021_RS10160	COG1690	Belongs to the RtcB family
acsn021_RS10175	COG5634	Uncharacterized conserved protein (DUF2278)
acsn021_RS10195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
acsn021_RS10220	COG2508	Transcriptional regulator
acsn021_RS10220	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
acsn021_RS10225	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
acsn021_RS10285	COG1393	Belongs to the ArsC family
acsn021_RS10290	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
acsn021_RS10325	COG0521	Mo-molybdopterin cofactor biosynthetic process
acsn021_RS10330	COG1606	tRNA processing
acsn021_RS10400	COG2223	nitrite transmembrane transporter activity
acsn021_RS10420	COG4221	oxidoreductase activity
acsn021_RS10440	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
acsn021_RS10450	COG0386	Belongs to the glutathione peroxidase family
acsn021_RS10455	COG3118	belongs to the thioredoxin family
acsn021_RS10460	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
acsn021_RS10465	COG1321	iron dependent repressor
acsn021_RS10470	COG1879	ABC-type sugar transport system periplasmic component
acsn021_RS10480	COG0765	amino acid transport
acsn021_RS10485	COG1126	abc transporter atp-binding protein
acsn021_RS10495	COG3858	chitin binding
acsn021_RS10495	COG1388	LysM domain
acsn021_RS10500	COG1846	Transcriptional regulator
acsn021_RS10505	COG0386	Belongs to the glutathione peroxidase family
acsn021_RS10510	COG0004	ammonium transporteR
acsn021_RS10515	COG1725	Transcriptional regulator
acsn021_RS10520	COG1131	(ABC) transporter
acsn021_RS10545	COG0395	ABC-type sugar transport system, permease component
acsn021_RS10565	COG1175	transmembrane transport
acsn021_RS10570	COG0395	ABC-type sugar transport system, permease component
acsn021_RS10580	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
acsn021_RS10585	COG1104	cysteine desulfurase activity
acsn021_RS10590	COG0037	tRNA processing
acsn021_RS10595	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
acsn021_RS10605	COG0287	Prephenate dehydrogenase
acsn021_RS10610	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
acsn021_RS10615	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
acsn021_RS10620	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
acsn021_RS10645	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
acsn021_RS10655	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
acsn021_RS10660	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
acsn021_RS10665	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
acsn021_RS10670	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
acsn021_RS10680	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
acsn021_RS10685	COG2135	peptidase activity
acsn021_RS10700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
acsn021_RS10710	COG2195	Cleaves the N-terminal amino acid of tripeptides
acsn021_RS10715	COG0129	dihydroxy-acid dehydratase activity
acsn021_RS10725	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
acsn021_RS10730	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
acsn021_RS10740	COG1785	Belongs to the alkaline phosphatase family
acsn021_RS10750	COG1687	branched-chain amino acid
acsn021_RS10755	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
acsn021_RS10765	COG1482	cell wall glycoprotein biosynthetic process
acsn021_RS10775	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
acsn021_RS10780	COG0668	transmembrane transport
acsn021_RS10800	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
acsn021_RS10805	COG0235	Class ii aldolase
acsn021_RS10815	COG1307	EDD domain protein, DegV family
acsn021_RS10825	COG1070	Carbohydrate kinase
acsn021_RS10830	COG4806	L-rhamnose isomerase
acsn021_RS10840	COG0235	Class ii aldolase
acsn021_RS10855	COG1063	alcohol dehydrogenase
acsn021_RS10880	COG4869	propanediol catabolic process
acsn021_RS10885	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
acsn021_RS10900	COG1349	DNA-binding transcription factor activity
acsn021_RS10905	COG1882	Formate acetyltransferase
acsn021_RS10910	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
acsn021_RS10955	COG3976	FMN-binding domain protein
acsn021_RS10955	COG1053	succinate dehydrogenase
acsn021_RS10965	COG0840	transmembrane signaling receptor activity
acsn021_RS10980	COG0512	Glutamine amidotransferase of anthranilate synthase
acsn021_RS10980	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
acsn021_RS10985	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
acsn021_RS10990	COG0134	indole-3-glycerol-phosphate synthase activity
acsn021_RS10995	COG0135	phosphoribosylanthranilate isomerase activity
acsn021_RS11000	COG0133	tryptophan synthase activity
acsn021_RS11015	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
acsn021_RS11025	COG1132	(ABC) transporter
acsn021_RS11060	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
acsn021_RS11065	COG2207	Transcriptional regulator
acsn021_RS11090	COG0840	transmembrane signaling receptor activity
acsn021_RS11095	COG3384	dioxygenase
acsn021_RS11100	COG1741	Belongs to the pirin family
acsn021_RS11105	COG0745	RESPONSE REGULATOR receiver
acsn021_RS11110	COG5002	protein histidine kinase activity
acsn021_RS11145	COG0778	Nitroreductase
acsn021_RS11160	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
acsn021_RS11175	COG1733	regulation of RNA biosynthetic process
acsn021_RS11210	COG2135	peptidase activity
acsn021_RS11240	COG1086	Polysaccharide biosynthesis protein
acsn021_RS11245	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
acsn021_RS11250	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
acsn021_RS11270	COG1216	Glycosyl transferase, family 2
acsn021_RS11270	COG1442	glycosyl transferase family 8
acsn021_RS11285	COG1086	Polysaccharide biosynthesis protein
acsn021_RS11325	COG1215	transferase activity, transferring glycosyl groups
acsn021_RS11340	COG1472	Belongs to the glycosyl hydrolase 3 family
acsn021_RS11380	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
acsn021_RS11405	COG0798	PFAM Bile acid sodium symporter
acsn021_RS11410	COG0640	Transcriptional regulator
acsn021_RS11415	COG0446	pyridine nucleotide-disulphide oxidoreductase
acsn021_RS11420	COG0640	Transcriptional regulator
acsn021_RS11430	COG1846	Transcriptional regulator
acsn021_RS11435	COG1247	-acetyltransferase
acsn021_RS11440	COG1649	PFAM Uncharacterised BCR, COG1649
acsn021_RS11445	COG2247	cell wall binding repeat
acsn021_RS11445	COG0860	N-Acetylmuramoyl-L-alanine amidase
acsn021_RS11450	COG4974	Belongs to the 'phage' integrase family
acsn021_RS11460	COG1132	(ABC) transporter
acsn021_RS11475	COG1309	transcriptional regulator
acsn021_RS11485	COG1131	(ABC) transporter
acsn021_RS11495	COG1918	ferrous iron import across plasma membrane
acsn021_RS11495	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
acsn021_RS11500	COG1918	ferrous iron import across plasma membrane
acsn021_RS11500	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
acsn021_RS11545	COG1760	l-serine dehydratase
acsn021_RS11550	COG1760	l-serine dehydratase
acsn021_RS11555	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
acsn021_RS11560	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
acsn021_RS11565	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
acsn021_RS11575	COG3534	alpha-L-arabinofuranosidase
acsn021_RS11590	COG0028	Belongs to the TPP enzyme family
acsn021_RS11595	COG0440	acetolactate synthase activity
acsn021_RS11610	COG0860	N-Acetylmuramoyl-L-alanine amidase
acsn021_RS11610	COG2247	cell wall binding repeat
acsn021_RS11620	COG0469	pyruvate kinase activity
acsn021_RS11630	COG0617	tRNA 3'-terminal CCA addition
acsn021_RS11635	COG0437	4 iron, 4 sulfur cluster binding
acsn021_RS11645	COG0822	iron-sulfur transferase activity
acsn021_RS11650	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
acsn021_RS11655	COG0719	Fe-S assembly protein
acsn021_RS11660	COG0719	Fe-S assembly protein
acsn021_RS11690	COG1737	Transcriptional regulator
acsn021_RS11695	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
acsn021_RS11700	COG0363	glucosamine-6-phosphate deaminase activity
acsn021_RS11705	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
acsn021_RS11715	COG1394	ATPase activity, coupled to movement of substances
acsn021_RS11720	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
acsn021_RS11725	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
acsn021_RS11740	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
acsn021_RS11745	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
acsn021_RS11750	COG1269	ATP hydrolysis coupled proton transport
acsn021_RS11780	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
acsn021_RS11790	COG0535	radical SAM domain protein
acsn021_RS11790	COG1433	Dinitrogenase iron-molybdenum cofactor
acsn021_RS11810	COG0347	Belongs to the P(II) protein family
acsn021_RS11815	COG0347	Belongs to the P(II) protein family
acsn021_RS11820	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
acsn021_RS11840	COG0745	RESPONSE REGULATOR receiver
acsn021_RS11870	COG0602	queuosine metabolic process
acsn021_RS11910	COG0697	spore germination
acsn021_RS11915	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
acsn021_RS11920	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
acsn021_RS11930	COG1408	metallophosphoesterase
acsn021_RS11935	COG1686	Belongs to the peptidase S11 family
acsn021_RS11965	COG1758	RNA polymerase activity
acsn021_RS11970	COG2052	Domain of unknown function (DUF370)
acsn021_RS11975	COG1561	YicC-like family, N-terminal region
acsn021_RS11985	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
acsn021_RS11990	COG0482	sulfurtransferase activity
acsn021_RS11995	COG0822	iron-sulfur transferase activity
acsn021_RS12015	COG5001	Diguanylate cyclase
acsn021_RS12020	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
acsn021_RS12040	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
acsn021_RS12050	COG1032	radical SAM domain protein
acsn021_RS12060	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
acsn021_RS12070	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
acsn021_RS12125	COG0318	PFAM AMP-dependent synthetase and ligase
acsn021_RS12140	COG4555	ABC transporter
acsn021_RS12145	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
acsn021_RS12165	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
acsn021_RS12165	COG2207	Transcriptional regulator
acsn021_RS12170	COG2376	Dihydroxyacetone kinase
acsn021_RS12190	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
acsn021_RS12200	COG0395	ABC-type sugar transport system, permease component
acsn021_RS12210	COG1501	Belongs to the glycosyl hydrolase 31 family
acsn021_RS12225	COG0583	DNA-binding transcription factor activity
acsn021_RS12235	COG3833	ABC-type maltose transport systems, permease component
acsn021_RS12240	COG1175	transmembrane transport
acsn021_RS12245	COG2182	Extracellular solute-binding protein
acsn021_RS12275	COG2746	aminoglycoside 3-N-acetyltransferase activity
acsn021_RS12280	COG1136	(ABC) transporter
acsn021_RS12285	COG0745	RESPONSE REGULATOR receiver
acsn021_RS12290	COG1136	(ABC) transporter
acsn021_RS12295	COG0577	efflux transmembrane transporter activity
acsn021_RS12300	COG2205	protein histidine kinase activity
acsn021_RS12305	COG0745	RESPONSE REGULATOR receiver
acsn021_RS12310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
acsn021_RS12335	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
acsn021_RS12340	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
acsn021_RS12345	COG1187	pseudouridine synthase activity
acsn021_RS12360	COG2323	membrane
acsn021_RS12395	COG5002	protein histidine kinase activity
acsn021_RS12400	COG2954	triphosphatase activity
acsn021_RS12415	COG2267	carboxylic ester hydrolase activity
acsn021_RS12420	COG0488	(ABC) transporter
acsn021_RS12425	COG2246	polysaccharide biosynthetic process
acsn021_RS12440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
acsn021_RS12445	COG0601	transmembrane transport
acsn021_RS12450	COG4608	Belongs to the ABC transporter superfamily
acsn021_RS12455	COG0444	Belongs to the ABC transporter superfamily
acsn021_RS12490	COG1595	DNA-templated transcription, initiation
acsn021_RS12515	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
acsn021_RS12520	COG1982	Orn Lys Arg decarboxylase major
acsn021_RS12525	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
acsn021_RS12530	COG0826	peptidase U32
acsn021_RS12535	COG4122	O-methyltransferase activity
acsn021_RS12545	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
acsn021_RS12550	COG0735	belongs to the Fur family
acsn021_RS12560	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
acsn021_RS12565	COG4472	Bacterial protein of unknown function (DUF965)
acsn021_RS12570	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
acsn021_RS12580	COG0301	tRNA thio-modification
acsn021_RS12585	COG1104	cysteine desulfurase activity
acsn021_RS12590	COG1385	rRNA (uridine-N3-)-methyltransferase activity
acsn021_RS12595	COG2264	protein methyltransferase activity
acsn021_RS12600	COG0484	heat shock protein binding
acsn021_RS12605	COG0443	Heat shock 70 kDa protein
acsn021_RS12610	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
acsn021_RS12615	COG1420	regulation of RNA biosynthetic process
acsn021_RS12620	COG0635	Involved in the biosynthesis of porphyrin-containing compound
acsn021_RS12625	COG0481	GTPase activity
acsn021_RS12635	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
acsn021_RS12640	COG0268	Binds directly to 16S ribosomal RNA
acsn021_RS12645	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
acsn021_RS12650	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
acsn021_RS12665	COG0799	negative regulation of ribosome biogenesis
acsn021_RS12670	COG1713	HD superfamily hydrolase involved in NAD metabolism
acsn021_RS12675	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
acsn021_RS12680	COG1534	Rna-binding protein
acsn021_RS12685	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
acsn021_RS12690	COG0211	Belongs to the bacterial ribosomal protein bL27 family
acsn021_RS12695	COG2868	ribosomal protein
acsn021_RS12700	COG0261	This protein binds to 23S rRNA in the presence of protein L20
acsn021_RS12710	COG3192	ethanolamine utilization protein
acsn021_RS12715	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
acsn021_RS12725	COG4820	ethanolamine utilization protein (EutJ)
acsn021_RS12730	COG4869	propanediol catabolic process
acsn021_RS12745	COG1012	belongs to the aldehyde dehydrogenase family
acsn021_RS12745	COG1454	alcohol dehydrogenase
acsn021_RS12765	COG4303	Ethanolamine ammonia lyase large subunit
acsn021_RS12795	COG0840	transmembrane signaling receptor activity
acsn021_RS12815	COG2304	oxidoreductase activity
acsn021_RS12830	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
acsn021_RS12835	COG1530	ribonuclease E activity
acsn021_RS12855	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
acsn021_RS12860	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
acsn021_RS12870	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
acsn021_RS12880	COG2116	formate transmembrane transporter activity
acsn021_RS12905	COG1686	Belongs to the peptidase S11 family
acsn021_RS12910	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
acsn021_RS12915	COG0252	asparaginase activity
acsn021_RS12920	COG1181	Belongs to the D-alanine--D-alanine ligase family
acsn021_RS12935	COG1924	4 iron, 4 sulfur cluster binding
acsn021_RS12960	COG0564	pseudouridine synthase activity
acsn021_RS12965	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
acsn021_RS12970	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
acsn021_RS12975	COG3599	regulation of cell shape
acsn021_RS12990	COG1799	cell septum assembly
acsn021_RS12995	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
acsn021_RS13005	COG2155	Conserved Protein
acsn021_RS13015	COG1686	Belongs to the peptidase S11 family
acsn021_RS13020	COG1803	Methylglyoxal synthase
acsn021_RS13030	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
acsn021_RS13035	COG2894	cell division
acsn021_RS13045	COG0768	penicillin binding
acsn021_RS13065	COG2003	Belongs to the UPF0758 family
acsn021_RS13075	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
acsn021_RS13080	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
acsn021_RS13090	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
acsn021_RS13095	COG0328	RNA-DNA hybrid ribonuclease activity
acsn021_RS13130	COG0395	ABC-type sugar transport system, permease component
acsn021_RS13135	COG4209	transmembrane transport
acsn021_RS13175	COG3064	Membrane
acsn021_RS13175	COG3583	domain protein
acsn021_RS13175	COG3525	Glycosyl hydrolase, family 20, catalytic domain
acsn021_RS13180	COG1472	Belongs to the glycosyl hydrolase 3 family
acsn021_RS13190	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
acsn021_RS13200	COG1408	metallophosphoesterase
acsn021_RS13210	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
acsn021_RS13215	COG3344	reverse transcriptase
acsn021_RS13225	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
acsn021_RS13235	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
acsn021_RS13240	COG1160	GTP binding
acsn021_RS13260	COG2226	methyltransferase
acsn021_RS13270	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
acsn021_RS13275	COG1496	oxidoreductase activity
acsn021_RS13280	COG0792	nuclease activity
acsn021_RS13285	COG2257	FlhB HrpN YscU SpaS Family
acsn021_RS13290	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
acsn021_RS13295	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
acsn021_RS13305	COG0335	large ribosomal subunit rRNA binding
acsn021_RS13315	COG0336	Belongs to the RNA methyltransferase TrmD family
acsn021_RS13320	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
acsn021_RS13330	COG0228	four-way junction DNA binding
acsn021_RS13335	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
acsn021_RS13355	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
acsn021_RS13365	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
acsn021_RS13370	COG0511	ligase activity, forming carbon-carbon bonds
acsn021_RS13380	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
acsn021_RS13385	COG2137	regulation of response to DNA damage stimulus
acsn021_RS13390	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
acsn021_RS13395	COG1247	-acetyltransferase
acsn021_RS13400	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
acsn021_RS13405	COG0552	protein localization to endoplasmic reticulum
acsn021_RS13410	COG1196	nuclear chromosome segregation
acsn021_RS13415	COG0571	ribonuclease III activity
acsn021_RS13420	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
acsn021_RS13425	COG0416	fatty acid biosynthetic process
acsn021_RS13430	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
acsn021_RS13435	COG0539	negative regulation of cytoplasmic translation
acsn021_RS13435	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
acsn021_RS13445	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
acsn021_RS13450	COG2081	HI0933 family
acsn021_RS13460	COG1058	Belongs to the CinA family
acsn021_RS13460	COG1546	Belongs to the CinA family
acsn021_RS13465	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
acsn021_RS13470	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
acsn021_RS13485	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
acsn021_RS13490	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
acsn021_RS13495	COG1609	Transcriptional regulator
acsn021_RS13505	COG0395	ABC-type sugar transport system, permease component
acsn021_RS13510	COG1175	transmembrane transport
acsn021_RS13535	COG2721	sulfolactate sulfo-lyase activity
acsn021_RS13540	COG0246	Mannitol dehydrogenase
acsn021_RS13545	COG1609	Transcriptional regulator
acsn021_RS13550	COG1904	glucuronate isomerase
acsn021_RS13560	COG0540	Belongs to the ATCase OTCase family
acsn021_RS13565	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
acsn021_RS13570	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
acsn021_RS13575	COG2759	Belongs to the formate--tetrahydrofolate ligase family
acsn021_RS13580	COG0546	phosphoglycolate phosphatase activity
acsn021_RS13585	COG0017	Asparaginyl-tRNA synthetase
acsn021_RS13615	COG0740	serine-type endopeptidase activity
acsn021_RS13620	COG0371	Dehydrogenase
acsn021_RS13625	COG0612	Peptidase, M16
acsn021_RS13640	COG2226	methyltransferase
acsn021_RS13650	COG4149	molybdate abc transporter
acsn021_RS13655	COG0725	ABC transporter, periplasmic molybdate-binding protein
acsn021_RS13660	COG1185	polyribonucleotide nucleotidyltransferase activity
acsn021_RS13665	COG0445	tRNA wobble uridine modification
acsn021_RS13670	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
acsn021_RS13675	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
acsn021_RS13680	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
acsn021_RS13685	COG0395	ABC-type sugar transport system, permease component
acsn021_RS13690	COG1175	transmembrane transport
acsn021_RS13700	COG2972	Histidine kinase
acsn021_RS13705	COG4753	response regulator
acsn021_RS13705	COG2207	Transcriptional regulator
acsn021_RS13710	COG2217	Heavy metal translocating P-type atpase
acsn021_RS13725	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
acsn021_RS13740	COG0504	CTP synthase activity
acsn021_RS13750	COG0789	Transcriptional regulator
acsn021_RS13760	COG1131	(ABC) transporter
acsn021_RS13765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
acsn021_RS13770	COG0196	riboflavin kinase activity
acsn021_RS13775	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
acsn021_RS13780	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
acsn021_RS13785	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
acsn021_RS13790	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
acsn021_RS13805	COG0195	Participates in both transcription termination and antitermination
acsn021_RS13810	COG0779	Required for maturation of 30S ribosomal subunits
acsn021_RS13820	COG0131	Imidazoleglycerol-phosphate dehydratase
acsn021_RS13825	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
acsn021_RS13830	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
acsn021_RS13835	COG0124	histidyl-tRNA synthetase
acsn021_RS13845	COG3331	DNA recombination
acsn021_RS13860	COG1187	pseudouridine synthase activity
acsn021_RS13865	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
acsn021_RS13865	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
acsn021_RS13870	COG2357	RelA SpoT domain protein
acsn021_RS13880	COG1316	TRANSCRIPTIONal
acsn021_RS13885	COG2843	Capsule synthesis protein
acsn021_RS13890	COG2195	Cleaves the N-terminal amino acid of tripeptides
acsn021_RS13895	COG2848	UPF0210 protein
acsn021_RS13905	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
acsn021_RS13910	COG0849	cell division
acsn021_RS13915	COG0237	dephospho-CoA kinase activity
acsn021_RS13920	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
acsn021_RS13920	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
acsn021_RS13935	COG0793	Belongs to the peptidase S41A family
acsn021_RS13935	COG3409	Peptidoglycan-binding domain 1 protein
acsn021_RS13960	COG1191	sigma factor activity
acsn021_RS13970	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
acsn021_RS13975	COG1776	CheC inhibitor of MCP methylation
acsn021_RS13985	COG2198	Histidine kinase
acsn021_RS13985	COG0643	Histidine kinase
acsn021_RS13990	COG2201	protein-glutamate methylesterase activity
acsn021_RS14005	COG1419	protein localization to endoplasmic reticulum
acsn021_RS14010	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
acsn021_RS14015	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
acsn021_RS14020	COG1684	flagellar biosynthetic protein fliR
acsn021_RS14025	COG1987	bacterial-type flagellum assembly
acsn021_RS14030	COG1338	Plays a role in the flagellum-specific transport system
acsn021_RS14040	COG2201	protein-glutamate methylesterase activity
acsn021_RS14045	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
acsn021_RS14045	COG1776	CheC inhibitor of MCP methylation
acsn021_RS14050	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
acsn021_RS14060	COG1360	Flagellar Motor Protein
acsn021_RS14070	COG1582	Flagellar protein (FlbD)
acsn021_RS14085	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
acsn021_RS14105	COG1157	protein secretion by the type III secretion system
acsn021_RS14115	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
acsn021_RS14125	COG1677	Flagellar hook-basal body complex protein FliE
acsn021_RS14130	COG1558	bacterial-type flagellum-dependent cell motility
acsn021_RS14135	COG1815	bacterial-type flagellum-dependent cell motility
acsn021_RS14145	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
acsn021_RS14150	COG0758	DNA mediated transformation
acsn021_RS14155	COG0606	chelatase, subunit chli
acsn021_RS14160	COG0519	Catalyzes the synthesis of GMP from XMP
acsn021_RS14165	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
acsn021_RS14180	COG1191	sigma factor activity
acsn021_RS14185	COG1191	sigma factor activity
acsn021_RS14195	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
acsn021_RS14205	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
acsn021_RS14210	COG0772	Belongs to the SEDS family
acsn021_RS14215	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
acsn021_RS14225	COG0768	penicillin binding
acsn021_RS14230	COG0768	penicillin binding
acsn021_RS14240	COG0275	rRNA processing
acsn021_RS14245	COG2001	Belongs to the MraZ family
acsn021_RS14250	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
acsn021_RS14255	COG0012	GTP binding
acsn021_RS14265	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
acsn021_RS14275	COG0515	serine threonine protein kinase
acsn021_RS14275	COG2815	serine threonine protein kinase
acsn021_RS14280	COG0631	protein serine/threonine phosphatase activity
acsn021_RS14285	COG0820	rRNA (adenine-C2-)-methyltransferase activity
acsn021_RS14290	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
acsn021_RS14290	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
acsn021_RS14295	COG2738	Putative neutral zinc metallopeptidase
acsn021_RS14305	COG0242	peptide deformylase activity
acsn021_RS14310	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
acsn021_RS14315	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
acsn021_RS14320	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
acsn021_RS14350	COG0395	ABC-type sugar transport system, permease component
acsn021_RS14370	COG0395	ABC-type sugar transport system, permease component
acsn021_RS14375	COG1175	transmembrane transport
acsn021_RS14390	COG3507	Belongs to the glycosyl hydrolase 43 family
acsn021_RS14395	COG3940	Belongs to the glycosyl hydrolase 43 family
acsn021_RS14415	COG1136	(ABC) transporter
acsn021_RS14420	COG0642	Histidine kinase
acsn021_RS14425	COG0745	RESPONSE REGULATOR receiver
acsn021_RS14430	COG1725	Transcriptional regulator
acsn021_RS14435	COG1131	(ABC) transporter
acsn021_RS14460	COG0242	peptide deformylase activity
acsn021_RS14465	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
acsn021_RS14470	COG4974	Belongs to the 'phage' integrase family
acsn021_RS14485	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
acsn021_RS14495	COG1418	mRNA catabolic process
acsn021_RS14500	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
acsn021_RS14515	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
acsn021_RS14520	COG1518	maintenance of DNA repeat elements
acsn021_RS14575	COG1404	Belongs to the peptidase S8 family
acsn021_RS14585	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
acsn021_RS14590	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
acsn021_RS14595	COG4224	UPF0291 protein
acsn021_RS14600	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
acsn021_RS14605	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
acsn021_RS14610	COG2081	HI0933 family
acsn021_RS14620	COG4176	ABC-type proline glycine betaine transport system permease component
acsn021_RS14635	COG1136	(ABC) transporter
acsn021_RS14685	COG0232	Belongs to the dGTPase family. Type 2 subfamily
acsn021_RS14690	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
acsn021_RS14695	COG0113	porphobilinogen synthase activity
acsn021_RS14705	COG0181	hydroxymethylbilane synthase activity
acsn021_RS14710	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
acsn021_RS14710	COG1648	precorrin-2 dehydrogenase activity
acsn021_RS14715	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
acsn021_RS14725	COG0495	leucyl-tRNA aminoacylation
acsn021_RS14735	COG0569	domain protein
acsn021_RS14740	COG4154	Belongs to the RbsD FucU family
acsn021_RS14745	COG1070	Carbohydrate kinase
acsn021_RS14750	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
acsn021_RS14770	COG2895	sulfate adenylyltransferase (ATP) activity
acsn021_RS14775	COG0175	sulfate reduction
acsn021_RS14780	COG2878	Part of a membrane complex involved in electron transport
acsn021_RS14780	COG1245	4Fe-4S binding domain
acsn021_RS14790	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
acsn021_RS14795	COG4208	sulfate ABC transporter
acsn021_RS14805	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
acsn021_RS14820	COG2244	polysaccharide biosynthetic process
acsn021_RS14830	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
acsn021_RS14840	COG1702	phosphate starvation-inducible protein PhoH
acsn021_RS14870	COG1175	transmembrane transport
acsn021_RS14880	COG5002	protein histidine kinase activity
acsn021_RS14885	COG0745	RESPONSE REGULATOR receiver
acsn021_RS14890	COG0828	Belongs to the bacterial ribosomal protein bS21 family
acsn021_RS14905	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
acsn021_RS14965	COG1983	PspC domain protein
acsn021_RS14990	COG2205	protein histidine kinase activity
acsn021_RS14995	COG0745	RESPONSE REGULATOR receiver
acsn021_RS15010	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
acsn021_RS15015	COG0750	zinc metalloprotease
acsn021_RS15020	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
acsn021_RS15025	COG4589	Belongs to the CDS family
acsn021_RS15030	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
acsn021_RS15035	COG0233	cytoplasmic translational termination
acsn021_RS15060	COG0673	inositol 2-dehydrogenase activity
acsn021_RS15065	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
acsn021_RS15070	COG0052	Belongs to the universal ribosomal protein uS2 family
acsn021_RS15075	COG1051	belongs to the nudix hydrolase family
acsn021_RS15085	COG0772	Belongs to the SEDS family
acsn021_RS15090	COG0826	peptidase U32
acsn021_RS15100	COG2255	four-way junction helicase activity
acsn021_RS15105	COG0632	four-way junction helicase activity
acsn021_RS15110	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
acsn021_RS15125	COG0333	Belongs to the bacterial ribosomal protein bL32 family
acsn021_RS15135	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
acsn021_RS15140	COG0280	phosphate acetyltransferase
acsn021_RS15145	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
acsn021_RS15165	COG3279	Response regulator of the LytR AlgR family
acsn021_RS15170	COG1323	Belongs to the UPF0348 family
acsn021_RS15175	COG1164	Oligoendopeptidase f
acsn021_RS15190	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
acsn021_RS15195	COG0742	ribosomal rna small subunit methyltransferase
acsn021_RS15210	COG0463	Glycosyl transferase, family 2
acsn021_RS15225	COG0463	Glycosyl transferase, family 2
acsn021_RS15230	COG0464	growth
acsn021_RS15235	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
acsn021_RS15240	COG1461	Dihydroxyacetone kinase
acsn021_RS15245	COG1302	Protein conserved in bacteria
acsn021_RS15255	COG0227	Belongs to the bacterial ribosomal protein bL28 family
acsn021_RS15295	COG0673	inositol 2-dehydrogenase activity
acsn021_RS15305	COG0673	inositol 2-dehydrogenase activity
acsn021_RS15310	COG0561	phosphatase activity
acsn021_RS15360	COG0488	(ABC) transporter
acsn021_RS15380	COG3620	sequence-specific DNA binding
acsn021_RS15390	COG5444	nuclease activity
acsn021_RS15415	COG3620	sequence-specific DNA binding
acsn021_RS15455	COG3620	sequence-specific DNA binding
acsn021_RS15495	COG2755	lipolytic protein G-D-S-L family
acsn021_RS15495	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
acsn021_RS15500	COG1388	LysM domain
acsn021_RS15500	COG0860	N-Acetylmuramoyl-L-alanine amidase
acsn021_RS15520	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
acsn021_RS15535	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
acsn021_RS15540	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
acsn021_RS15545	COG0583	DNA-binding transcription factor activity
acsn021_RS15550	COG0107	imidazoleglycerol-phosphate synthase activity
acsn021_RS15555	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
acsn021_RS15565	COG0784	Response regulator, receiver
acsn021_RS15565	COG0835	chemotaxis
acsn021_RS15595	COG2205	protein histidine kinase activity
acsn021_RS15600	COG2337	Toxic component of a toxin-antitoxin (TA) module
acsn021_RS15605	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
acsn021_RS15610	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
acsn021_RS15610	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
acsn021_RS15620	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
acsn021_RS15625	COG0488	(ABC) transporter
acsn021_RS15630	COG1802	Transcriptional regulator
acsn021_RS15635	COG0473	3-isopropylmalate dehydrogenase activity
acsn021_RS15640	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
acsn021_RS15645	COG0549	Belongs to the carbamate kinase family
acsn021_RS15655	COG0367	asparagine synthase
acsn021_RS15660	COG0840	transmembrane signaling receptor activity
acsn021_RS15660	COG3290	protein histidine kinase activity
acsn021_RS15670	COG1464	Belongs to the NlpA lipoprotein family
acsn021_RS15675	COG2011	ABC-type metal ion transport system permease component
acsn021_RS15680	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
acsn021_RS15685	COG0674	pyruvate-flavodoxin oxidoreductase activity
acsn021_RS15685	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
acsn021_RS15685	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
acsn021_RS15685	COG1013	pyruvate-flavodoxin oxidoreductase activity
acsn021_RS15695	COG3300	MHYT domain
acsn021_RS15695	COG5001	Diguanylate cyclase
acsn021_RS15700	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
acsn021_RS15710	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
acsn021_RS15715	COG1802	Transcriptional regulator
acsn021_RS15720	COG0246	Mannitol dehydrogenase
acsn021_RS15725	COG1312	Catalyzes the dehydration of D-mannonate
acsn021_RS15745	COG0840	transmembrane signaling receptor activity
acsn021_RS15760	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
acsn021_RS15765	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
acsn021_RS15770	COG1404	Belongs to the peptidase S8 family
acsn021_RS15775	COG1592	Rubrerythrin
acsn021_RS15780	COG1013	pyruvate-flavodoxin oxidoreductase activity
acsn021_RS15785	COG0674	pyruvate-flavodoxin oxidoreductase activity
acsn021_RS15785	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
acsn021_RS15810	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
acsn021_RS15815	COG1396	sequence-specific DNA binding
acsn021_RS15820	COG3842	ATPase activity
acsn021_RS15825	COG1176	ABC-type spermidine putrescine transport system, permease component I
acsn021_RS15830	COG1177	transmembrane transport
acsn021_RS15835	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
acsn021_RS15840	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
acsn021_RS15855	COG1854	S-ribosylhomocysteine lyase activity
acsn021_RS15875	COG2201	protein-glutamate methylesterase activity
acsn021_RS15885	COG0840	transmembrane signaling receptor activity
acsn021_RS15890	COG0835	chemotaxis
acsn021_RS15895	COG0643	Histidine kinase
acsn021_RS15895	COG2198	Histidine kinase
acsn021_RS15900	COG2201	protein-glutamate methylesterase activity
acsn021_RS15905	COG1376	ErfK ybiS ycfS ynhG family protein
acsn021_RS15910	COG1132	(ABC) transporter
acsn021_RS15920	COG0534	Mate efflux family protein
acsn021_RS15940	COG4166	transmembrane transport
acsn021_RS15945	COG4608	Belongs to the ABC transporter superfamily
acsn021_RS15950	COG0444	Belongs to the ABC transporter superfamily
acsn021_RS15955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
acsn021_RS15960	COG0601	transmembrane transport
acsn021_RS15970	COG0148	phosphopyruvate hydratase activity
acsn021_RS15975	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
acsn021_RS15980	COG0165	Argininosuccinate lyase
acsn021_RS15985	COG5658	integral membrane protein
acsn021_RS15990	COG0640	Transcriptional regulator
acsn021_RS16000	COG1131	(ABC) transporter
acsn021_RS16010	COG1937	Protein conserved in bacteria
acsn021_RS16015	COG2217	Heavy metal translocating P-type atpase
acsn021_RS16025	COG0129	dihydroxy-acid dehydratase activity
acsn021_RS16050	COG1595	DNA-templated transcription, initiation
acsn021_RS16065	COG5002	protein histidine kinase activity
acsn021_RS16075	COG1555	photosystem II stabilization
acsn021_RS16075	COG1596	polysaccharide export
acsn021_RS16085	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
acsn021_RS16090	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
acsn021_RS16095	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
acsn021_RS16100	COG0424	maF-like protein
acsn021_RS16105	COG0137	argininosuccinate synthase activity
acsn021_RS16125	COG0561	phosphatase activity
acsn021_RS16130	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
acsn021_RS16140	COG1126	abc transporter atp-binding protein
acsn021_RS16145	COG0765	amino acid transport
acsn021_RS16155	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
acsn021_RS16165	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
acsn021_RS16180	COG2966	Psort location CytoplasmicMembrane, score
acsn021_RS16195	COG5002	protein histidine kinase activity
acsn021_RS16200	COG0745	RESPONSE REGULATOR receiver
acsn021_RS16205	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
acsn021_RS16230	COG3942	CHAP domain
acsn021_RS16230	COG1388	LysM domain
acsn021_RS16260	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
acsn021_RS16265	COG0557	exoribonuclease II activity
acsn021_RS16270	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
acsn021_RS16275	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
acsn021_RS16280	COG0149	triose-phosphate isomerase activity
acsn021_RS16305	COG0297	glycogen (starch) synthase activity
acsn021_RS16310	COG0745	RESPONSE REGULATOR receiver
acsn021_RS16315	COG0750	zinc metalloprotease
acsn021_RS16320	COG0497	DNA recombination
acsn021_RS16325	COG0643	Histidine kinase
acsn021_RS16325	COG2198	Histidine kinase
acsn021_RS16330	COG2201	protein-glutamate methylesterase activity
acsn021_RS16395	COG0217	transcriptional regulatory protein
acsn021_RS16400	COG1438	arginine binding
acsn021_RS16405	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
acsn021_RS16410	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
acsn021_RS16415	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
acsn021_RS16425	COG1722	exodeoxyribonuclease VII activity
acsn021_RS16430	COG1570	exodeoxyribonuclease VII activity
acsn021_RS16435	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
acsn021_RS16440	COG1302	Protein conserved in bacteria
acsn021_RS16480	COG3854	ATPases associated with a variety of cellular activities
acsn021_RS16485	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
acsn021_RS16495	COG0066	3-isopropylmalate dehydratase activity
acsn021_RS16500	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
acsn021_RS16505	COG0473	3-isopropylmalate dehydrogenase activity
acsn021_RS16510	COG0583	DNA-binding transcription factor activity
acsn021_RS16520	COG1194	a g-specific adenine glycosylase
acsn021_RS16525	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
acsn021_RS16530	COG0440	acetolactate synthase activity
acsn021_RS16545	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
acsn021_RS16550	COG1605	Chorismate mutase
acsn021_RS16550	COG0077	Prephenate dehydratase
acsn021_RS16555	COG0285	dihydrofolate synthase activity
acsn021_RS16560	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
acsn021_RS16570	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
acsn021_RS16585	COG0632	four-way junction helicase activity
acsn021_RS16600	COG1131	(ABC) transporter
acsn021_RS16610	COG2197	response regulator
acsn021_RS16620	COG4608	Belongs to the ABC transporter superfamily
acsn021_RS16620	COG4608	Belongs to the ABC transporter superfamily
acsn021_RS16625	COG0444	Belongs to the ABC transporter superfamily
acsn021_RS16635	COG0601	transmembrane transport
acsn021_RS16640	COG0747	negative chemotaxis
acsn021_RS16660	COG1307	EDD domain protein, DegV family
acsn021_RS16665	COG1116	anion transmembrane transporter activity
acsn021_RS16685	COG1116	anion transmembrane transporter activity
acsn021_RS16690	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
acsn021_RS16720	COG1523	belongs to the glycosyl hydrolase 13 family
acsn021_RS16735	COG1132	(ABC) transporter
acsn021_RS16755	COG1131	(ABC) transporter
acsn021_RS16760	COG0488	(ABC) transporter
acsn021_RS16775	COG4536	flavin adenine dinucleotide binding
acsn021_RS16790	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
acsn021_RS16795	COG0167	dihydroorotate dehydrogenase activity
acsn021_RS16815	COG0463	Glycosyl transferase, family 2
acsn021_RS16820	COG4485	Bacterial membrane protein, YfhO
acsn021_RS16825	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
acsn021_RS16830	COG0006	proline dipeptidase activity
acsn021_RS16835	COG0626	cystathionine gamma-synthase activity
acsn021_RS16840	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
acsn021_RS16845	COG0284	orotidine-5'-phosphate decarboxylase activity
acsn021_RS16870	COG2190	(PTS) system
acsn021_RS16870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
acsn021_RS16870	COG1263	PTS System
acsn021_RS16880	COG0745	RESPONSE REGULATOR receiver
acsn021_RS16885	COG5002	protein histidine kinase activity
acsn021_RS16915	COG1115	amino acid carrier protein
acsn021_RS16930	COG3708	Transcriptional regulator
acsn021_RS16930	COG2207	Transcriptional regulator
acsn021_RS16940	COG1476	TRANSCRIPTIONal
acsn021_RS16950	COG2207	Transcriptional regulator
acsn021_RS16950	COG3708	Transcriptional regulator
acsn021_RS17005	COG2207	Transcriptional regulator
acsn021_RS17020	COG0789	Transcriptional regulator
acsn021_RS17020	COG4978	Transcriptional regulator
acsn021_RS17025	COG5297	Belongs to the glycosyl hydrolase family 6
acsn021_RS17045	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
acsn021_RS17050	COG0018	arginyl-trna synthetase
acsn021_RS17095	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
acsn021_RS17100	COG0318	PFAM AMP-dependent synthetase and ligase
acsn021_RS17110	COG1917	Cupin 2, conserved barrel domain protein
acsn021_RS17110	COG2207	Transcriptional regulator
acsn021_RS17115	COG1132	(ABC) transporter
acsn021_RS17120	COG1132	(ABC) transporter
acsn021_RS17125	COG0737	Belongs to the 5'-nucleotidase family
acsn021_RS17145	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
acsn021_RS17160	COG0583	DNA-binding transcription factor activity
acsn021_RS17210	COG1472	Belongs to the glycosyl hydrolase 3 family
acsn021_RS17225	COG0395	ABC-type sugar transport system, permease component
acsn021_RS17230	COG4209	transmembrane transport
acsn021_RS17235	COG4753	response regulator
acsn021_RS17235	COG2207	Transcriptional regulator
acsn021_RS17240	COG2972	Histidine kinase
acsn021_RS17250	COG1501	Belongs to the glycosyl hydrolase 31 family
acsn021_RS17270	COG0626	cystathionine gamma-synthase activity
acsn021_RS17275	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
acsn021_RS17280	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
acsn021_RS17320	COG1285	pathogenesis
acsn021_RS17325	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
acsn021_RS17330	COG1802	Transcriptional regulator
acsn021_RS17360	COG1151	hydroxylamine reductase activity
acsn021_RS17365	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
acsn021_RS17375	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
acsn021_RS17385	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
acsn021_RS17385	COG1328	CTP reductase activity
acsn021_RS17395	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
acsn021_RS17415	COG0640	Transcriptional regulator
acsn021_RS17420	COG0673	inositol 2-dehydrogenase activity
acsn021_RS17425	COG0673	inositol 2-dehydrogenase activity
acsn021_RS17430	COG1082	Xylose isomerase domain protein TIM barrel
acsn021_RS17455	COG2207	Transcriptional regulator
acsn021_RS17455	COG4753	response regulator
acsn021_RS17460	COG2972	Histidine kinase
acsn021_RS17470	COG0395	ABC-type sugar transport system, permease component
acsn021_RS17475	COG4209	transmembrane transport
acsn021_RS17480	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
acsn021_RS17485	COG0248	Ppx GppA phosphatase
acsn021_RS17500	COG1113	amino acid transport
acsn021_RS17505	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
acsn021_RS17510	COG0583	DNA-binding transcription factor activity
acsn021_RS17550	COG3845	ABC transporter
acsn021_RS17560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
acsn021_RS17565	COG1609	Transcriptional regulator
acsn021_RS17625	COG3708	Transcriptional regulator
acsn021_RS17625	COG2207	Transcriptional regulator
acsn021_RS17635	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
acsn021_RS17640	COG0493	'glutamate synthase
acsn021_RS17655	COG1132	(ABC) transporter
acsn021_RS17695	COG1028	Short-chain dehydrogenase reductase Sdr
acsn021_RS17710	COG0148	phosphopyruvate hydratase activity
acsn021_RS17720	COG0475	glutathione-regulated potassium exporter activity
acsn021_RS17735	COG4555	ABC transporter
acsn021_RS17750	COG0024	Methionine aminopeptidase
acsn021_RS17790	COG0745	RESPONSE REGULATOR receiver
acsn021_RS17800	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
acsn021_RS17805	COG3958	Transketolase
acsn021_RS17810	COG3959	Transketolase, thiamine diphosphate binding domain
acsn021_RS17820	COG1609	Transcriptional regulator
acsn021_RS17835	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
acsn021_RS17845	COG1132	(ABC) transporter
acsn021_RS17850	COG1132	(ABC) transporter
acsn021_RS17865	COG1476	TRANSCRIPTIONal
acsn021_RS17880	COG3639	organic phosphonate transmembrane transporter activity
acsn021_RS17885	COG3639	organic phosphonate transmembrane transporter activity
acsn021_RS17900	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
acsn021_RS17905	COG1609	Transcriptional regulator
acsn021_RS17910	COG1053	succinate dehydrogenase
acsn021_RS17925	COG0484	heat shock protein binding
acsn021_RS17940	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
acsn021_RS17945	COG0488	(ABC) transporter
acsn021_RS17960	COG3973	AAA domain
acsn021_RS17970	COG0656	L-ascorbic acid biosynthetic process
acsn021_RS17980	COG1131	(ABC) transporter
acsn021_RS17990	COG0312	modulator of DNA gyrase
acsn021_RS18000	COG3250	beta-galactosidase activity
acsn021_RS18035	COG3842	ATPase activity
acsn021_RS18060	COG2378	regulation of single-species biofilm formation
acsn021_RS18065	COG1132	(ABC) transporter
acsn021_RS18070	COG4988	ABC transporter
acsn021_RS18075	COG2832	Protein of unknown function (DUF454)
acsn021_RS18090	COG0701	Predicted permease
acsn021_RS18095	COG0523	cobalamin synthesis protein
acsn021_RS18100	COG1108	ABC-type Mn2 Zn2 transport systems permease components
acsn021_RS18105	COG1121	(ABC) transporter
acsn021_RS18110	COG0803	Belongs to the bacterial solute-binding protein 9 family
acsn021_RS18135	COG0735	belongs to the Fur family
acsn021_RS18155	COG0298	carbon dioxide binding
acsn021_RS18200	COG0406	alpha-ribazole phosphatase activity
acsn021_RS18205	COG3290	protein histidine kinase activity
acsn021_RS18205	COG0840	transmembrane signaling receptor activity
acsn021_RS18215	COG2706	6-phosphogluconolactonase activity
acsn021_RS18245	COG0395	ABC-type sugar transport system, permease component
acsn021_RS18250	COG4209	transmembrane transport
acsn021_RS18255	COG1609	Transcriptional regulator
acsn021_RS18265	COG0741	lytic transglycosylase activity
acsn021_RS18280	COG1609	Transcriptional regulator
acsn021_RS18290	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
acsn021_RS18290	COG0426	domain, Protein
acsn021_RS18315	COG2033	superoxide reductase activity
acsn021_RS18325	COG1773	rubredoxin
acsn021_RS18330	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
acsn021_RS18335	COG1803	Methylglyoxal synthase
acsn021_RS18340	COG0372	Belongs to the citrate synthase family
acsn021_RS18350	COG3833	ABC-type maltose transport systems, permease component
acsn021_RS18355	COG1175	transmembrane transport
acsn021_RS18365	COG1917	Cupin 2, conserved barrel domain protein
acsn021_RS18365	COG2207	Transcriptional regulator
acsn021_RS18370	COG1609	Transcriptional regulator
acsn021_RS18390	COG0825	malonyl-CoA metabolic process
acsn021_RS18395	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
acsn021_RS18400	COG0439	Biotin carboxylase
acsn021_RS18410	COG0511	ligase activity, forming carbon-carbon bonds
acsn021_RS18415	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
acsn021_RS18420	COG1028	Short-chain dehydrogenase reductase Sdr
acsn021_RS18425	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
acsn021_RS18430	COG2070	2-Nitropropane dioxygenase
acsn021_RS18435	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
acsn021_RS18450	COG1396	sequence-specific DNA binding
acsn021_RS18465	COG0653	protein targeting
acsn021_RS18485	COG1132	(ABC) transporter
acsn021_RS18490	COG1132	(ABC) transporter
acsn021_RS18495	COG1773	rubredoxin
acsn021_RS18495	COG1592	Rubrerythrin
acsn021_RS18500	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
acsn021_RS18505	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
acsn021_RS18510	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
acsn021_RS18520	COG5566	PFAM Mor transcription activator
acsn021_RS18530	COG1511	domain protein
acsn021_RS18535	COG1959	2 iron, 2 sulfur cluster binding
acsn021_RS18540	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
acsn021_RS18555	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
acsn021_RS18565	COG1739	Uncharacterized protein family UPF0029
acsn021_RS18585	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
acsn021_RS18635	COG0525	valine-tRNA ligase activity
acsn021_RS18660	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
acsn021_RS18700	COG0367	asparagine synthase
acsn021_RS18760	COG1250	3-hydroxyacyl-CoA dehydrogenase
acsn021_RS18775	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
acsn021_RS18805	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
acsn021_RS18815	COG3401	FG-GAP repeat protein
acsn021_RS18820	COG1653	transport
acsn021_RS18825	COG0395	ABC-type sugar transport system, permease component
acsn021_RS18830	COG4209	transmembrane transport
acsn021_RS18835	COG2207	Transcriptional regulator
acsn021_RS18840	COG2755	lipolytic protein G-D-S-L family
acsn021_RS18845	COG3401	FG-GAP repeat protein
acsn021_RS18855	COG1683	Conserved Protein
acsn021_RS18860	COG0756	dUTP diphosphatase activity
acsn021_RS18865	COG0583	DNA-binding transcription factor activity
acsn021_RS18875	COG2388	GCN5-related N-acetyl-transferase
acsn021_RS18885	COG0840	transmembrane signaling receptor activity
acsn021_RS18890	COG1028	Short-chain dehydrogenase reductase Sdr
acsn021_RS18905	COG1012	belongs to the aldehyde dehydrogenase family
acsn021_RS18910	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
acsn021_RS18915	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
acsn021_RS18920	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
acsn021_RS18930	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
acsn021_RS18935	COG2226	methyltransferase
acsn021_RS18945	COG1070	Carbohydrate kinase
acsn021_RS18965	COG1597	lipid kinase activity
acsn021_RS18975	COG0840	transmembrane signaling receptor activity
acsn021_RS18980	COG1074	ATP-dependent DNA helicase activity
acsn021_RS18985	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
acsn021_RS18995	COG1307	EDD domain protein, DegV family
acsn021_RS19010	COG5002	protein histidine kinase activity
acsn021_RS19010	COG3850	Histidine kinase
acsn021_RS19015	COG0745	RESPONSE REGULATOR receiver
acsn021_RS19025	COG2268	Band 7 protein
acsn021_RS19040	COG0138	bifunctional purine biosynthesis protein purh
acsn021_RS19050	COG5002	protein histidine kinase activity
acsn021_RS19055	COG0745	RESPONSE REGULATOR receiver
acsn021_RS19060	COG0704	Plays a role in the regulation of phosphate uptake
acsn021_RS19065	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
acsn021_RS19070	COG0581	inorganic phosphate transmembrane transporter activity
acsn021_RS19075	COG0573	inorganic phosphate transmembrane transporter activity
acsn021_RS19080	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
acsn021_RS19095	COG0516	GMP reductase activity
acsn021_RS19095	COG0517	IMP dehydrogenase activity
acsn021_RS19105	COG0459	protein refolding
acsn021_RS19110	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
acsn021_RS19130	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
acsn021_RS19135	COG0436	Aminotransferase
acsn021_RS19155	COG0411	ABC transporter
acsn021_RS19190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
acsn021_RS19200	COG1316	TRANSCRIPTIONal
acsn021_RS19205	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
acsn021_RS19215	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
acsn021_RS19220	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
acsn021_RS19240	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
acsn021_RS19255	COG0840	transmembrane signaling receptor activity
acsn021_RS19265	COG0641	radical SAM
acsn021_RS19270	COG3119	arylsulfatase activity
acsn021_RS19270	COG3408	Glycogen debranching enzyme
acsn021_RS19280	COG3119	arylsulfatase activity
acsn021_RS19285	COG4211	Belongs to the binding-protein-dependent transport system permease family
acsn021_RS19300	COG1129	ABC transporter
acsn021_RS19305	COG3119	arylsulfatase activity
acsn021_RS19310	COG1472	Belongs to the glycosyl hydrolase 3 family
acsn021_RS19315	COG3119	arylsulfatase activity
acsn021_RS19320	COG2204	response regulator
acsn021_RS19325	COG3275	phosphorelay sensor kinase activity
acsn021_RS19340	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
acsn021_RS19345	COG2207	Transcriptional regulator
acsn021_RS19365	COG4584	PFAM Integrase catalytic
acsn021_RS19380	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
acsn021_RS19385	COG2226	methyltransferase
acsn021_RS19540	COG2003	Belongs to the UPF0758 family
acsn021_RS19615	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
acsn021_RS19630	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
acsn021_RS19665	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
acsn021_RS19675	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
acsn021_RS19675	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
acsn021_RS19675	COG1013	pyruvate-flavodoxin oxidoreductase activity
acsn021_RS19675	COG0674	pyruvate-flavodoxin oxidoreductase activity
acsn021_RS19690	COG0745	RESPONSE REGULATOR receiver
acsn021_RS19695	COG2205	protein histidine kinase activity
acsn021_RS19705	COG0840	transmembrane signaling receptor activity
acsn021_RS19720	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
acsn021_RS19725	COG1492	cobalamin metabolic process
acsn021_RS19730	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
acsn021_RS19750	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
acsn021_RS19760	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
acsn021_RS19765	COG1797	cobyrinic acid a,c-diamide synthase activity
acsn021_RS19795	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
acsn021_RS19825	COG0310	cobalt ion transport
acsn021_RS19840	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
acsn021_RS19850	COG0395	ABC-type sugar transport system, permease component
acsn021_RS19855	COG4209	transmembrane transport
acsn021_RS19865	COG2755	lipolytic protein G-D-S-L family
acsn021_RS19880	COG0824	Thioesterase
acsn021_RS19895	COG0584	glycerophosphoryl diester phosphodiesterase
acsn021_RS19925	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
acsn021_RS19930	COG1278	Cold shock
acsn021_RS19945	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
acsn021_RS19980	COG4209	transmembrane transport
acsn021_RS19985	COG0395	ABC-type sugar transport system, permease component
acsn021_RS19995	COG0129	dihydroxy-acid dehydratase activity
acsn021_RS20005	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
acsn021_RS20010	COG5426	von Willebrand factor, type A
acsn021_RS20015	COG2340	Cysteine-rich secretory protein family
acsn021_RS20025	COG1132	(ABC) transporter
acsn021_RS20030	COG1132	(ABC) transporter
acsn021_RS20035	COG1032	radical SAM domain protein
acsn021_RS20040	COG3655	Transcriptional regulator
acsn021_RS20055	COG1671	Belongs to the UPF0178 family
acsn021_RS20065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
acsn021_RS20070	COG0601	transmembrane transport
acsn021_RS20075	COG0747	negative chemotaxis
acsn021_RS20080	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
acsn021_RS20085	COG3459	Glycosyltransferase 36 associated
acsn021_RS20110	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
acsn021_RS20115	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
acsn021_RS20130	COG0840	transmembrane signaling receptor activity
acsn021_RS20135	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
acsn021_RS20135	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
acsn021_RS20145	COG1368	sulfuric ester hydrolase activity
acsn021_RS20160	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
acsn021_RS20170	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
acsn021_RS20175	COG2890	protein-(glutamine-N5) methyltransferase activity
acsn021_RS20180	COG3872	metal-dependent enzyme
acsn021_RS20185	COG0254	rRNA binding
acsn021_RS20190	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
acsn021_RS20195	COG0281	malic enzyme
acsn021_RS20200	COG1242	4 iron, 4 sulfur cluster binding
acsn021_RS20210	COG0218	Necessary for normal cell division and for the maintenance of normal septation
acsn021_RS20215	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
acsn021_RS20220	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
acsn021_RS20230	COG0544	peptidyl-prolyl cis-trans isomerase activity
acsn021_RS20235	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
acsn021_RS20245	COG1115	amino acid carrier protein
acsn021_RS20255	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
acsn021_RS20265	COG4603	Belongs to the binding-protein-dependent transport system permease family
acsn021_RS20270	COG3845	ABC transporter
acsn021_RS20280	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
acsn021_RS20295	COG3328	transposase activity
acsn021_RS20300	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
acsn021_RS20315	COG0402	S-adenosylhomocysteine deaminase activity
acsn021_RS20330	COG1733	regulation of RNA biosynthetic process
acsn021_RS20340	COG1216	Glycosyl transferase, family 2
acsn021_RS20345	COG0596	Alpha beta hydrolase
acsn021_RS20395	COG2337	Toxic component of a toxin-antitoxin (TA) module
acsn021_RS20415	COG1136	(ABC) transporter
acsn021_RS20425	COG0745	RESPONSE REGULATOR receiver
acsn021_RS20440	COG0577	efflux transmembrane transporter activity
acsn021_RS20445	COG1136	(ABC) transporter
acsn021_RS20450	COG2205	protein histidine kinase activity
acsn021_RS20455	COG0745	RESPONSE REGULATOR receiver
acsn021_RS20540	COG1196	nuclear chromosome segregation
acsn021_RS20540	COG0741	lytic transglycosylase activity
acsn021_RS20540	COG0739	heme binding
acsn021_RS20550	COG3976	FMN-binding domain protein
acsn021_RS20550	COG1053	succinate dehydrogenase
acsn021_RS20580	COG0798	PFAM Bile acid sodium symporter
acsn021_RS20685	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
acsn021_RS20695	COG2088	sporulation resulting in formation of a cellular spore
acsn021_RS20780	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
acsn021_RS20785	COG2247	cell wall binding repeat
acsn021_RS20785	COG0860	N-Acetylmuramoyl-L-alanine amidase
acsn021_RS20790	COG0116	Belongs to the methyltransferase superfamily
acsn021_RS20805	COG1132	(ABC) transporter
acsn021_RS20810	COG1132	(ABC) transporter
acsn021_RS20815	COG3290	protein histidine kinase activity
acsn021_RS20820	COG3279	Response regulator of the LytR AlgR family
acsn021_RS20905	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
acsn021_RS20920	COG1234	tRNA 3'-trailer cleavage
acsn021_RS20935	COG1214	PFAM Peptidase M22, glycoprotease
acsn021_RS20940	COG0802	atpase or kinase
acsn021_RS20950	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
acsn021_RS20965	COG1132	(ABC) transporter
acsn021_RS20990	COG3944	biosynthesis protein
acsn021_RS20995	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
acsn021_RS21020	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
acsn021_RS21030	COG2183	response to ionizing radiation
acsn021_RS21035	COG2116	formate transmembrane transporter activity
acsn021_RS21045	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
acsn021_RS21050	COG0460	homoserine dehydrogenase
acsn021_RS21055	COG4492	Belongs to the UPF0735 family
acsn021_RS21075	COG0653	protein targeting
acsn021_RS21110	COG0251	oxidation-reduction process
acsn021_RS21120	COG2996	Protein conserved in bacteria
acsn021_RS21130	COG1040	competence protein
acsn021_RS21140	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
acsn021_RS21155	COG4786	Flagellar basal body rod
acsn021_RS21175	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
acsn021_RS21180	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
acsn021_RS21185	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
acsn021_RS21190	COG0049	tRNA binding
acsn021_RS21195	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
acsn021_RS21210	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
acsn021_RS21215	COG0085	RNA polymerase activity
acsn021_RS21220	COG0222	ribosome binding
acsn021_RS21230	COG0081	regulation of translation
acsn021_RS21235	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
acsn021_RS21240	COG0250	Participates in transcription elongation, termination and antitermination
acsn021_RS21250	COG0267	Belongs to the bacterial ribosomal protein bL33 family
acsn021_RS21255	COG0395	ABC-type sugar transport system, permease component
acsn021_RS21260	COG1175	transmembrane transport
acsn021_RS21270	COG1609	Transcriptional regulator
acsn021_RS21280	COG2878	Part of a membrane complex involved in electron transport
acsn021_RS21285	COG4657	Part of a membrane complex involved in electron transport
acsn021_RS21290	COG4660	Part of a membrane complex involved in electron transport
acsn021_RS21295	COG4659	FMN binding
acsn021_RS21300	COG4658	electron transport chain
acsn021_RS21305	COG4656	Part of a membrane complex involved in electron transport
acsn021_RS21315	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
acsn021_RS21345	COG1725	Transcriptional regulator
acsn021_RS21350	COG2252	PERMEase
acsn021_RS21355	COG0598	Magnesium transport protein CorA
acsn021_RS21385	COG1609	Transcriptional regulator
acsn021_RS21395	COG1477	protein flavinylation
acsn021_RS21400	COG4656	Part of a membrane complex involved in electron transport
acsn021_RS21405	COG4658	electron transport chain
acsn021_RS21425	COG2814	Major facilitator Superfamily
acsn021_RS21430	COG3711	transcriptional antiterminator
acsn021_RS21435	COG2723	6-phospho-beta-galactosidase activity
acsn021_RS21440	COG1263	PTS System
acsn021_RS21440	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
acsn021_RS21440	COG2190	(PTS) system
acsn021_RS21455	COG1490	D-aminoacyl-tRNA deacylase activity
acsn021_RS21460	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
acsn021_RS21470	COG0463	Glycosyl transferase, family 2
acsn021_RS21480	COG2309	aminopeptidase activity
acsn021_RS21505	COG0698	ribose 5-phosphate isomerase
acsn021_RS21510	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
acsn021_RS21515	COG0009	L-threonylcarbamoyladenylate synthase
acsn021_RS21520	COG0860	N-Acetylmuramoyl-L-alanine amidase
acsn021_RS21540	COG4862	establishment of competence for transformation
acsn021_RS21555	COG0789	Transcriptional regulator
acsn021_RS21560	COG0305	Participates in initiation and elongation during chromosome replication
acsn021_RS21565	COG0359	binds to the 23S rRNA
acsn021_RS21570	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
acsn021_RS21595	COG1442	glycosyl transferase family 8
acsn021_RS21595	COG1216	Glycosyl transferase, family 2
acsn021_RS21600	COG0438	transferase activity, transferring glycosyl groups
acsn021_RS21615	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
acsn021_RS21640	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
acsn021_RS21650	COG3103	Sh3 type 3 domain protein
acsn021_RS21650	COG0366	Alpha amylase catalytic
acsn021_RS21660	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
acsn021_RS21665	COG0629	single-stranded DNA binding
acsn021_RS21670	COG0360	Binds together with S18 to 16S ribosomal RNA
acsn021_RS21680	COG1136	(ABC) transporter
acsn021_RS21685	COG2070	2-Nitropropane dioxygenase
acsn021_RS21690	COG0668	transmembrane transport
acsn021_RS21695	COG0659	secondary active sulfate transmembrane transporter activity
acsn021_RS21715	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
acsn021_RS21745	COG0395	ABC-type sugar transport system, permease component
acsn021_RS21750	COG4209	transmembrane transport
acsn021_RS21760	COG3534	alpha-L-arabinofuranosidase
acsn021_RS21765	COG1940	carbohydrate kinase activity
acsn021_RS21770	COG4481	Protein conserved in bacteria
acsn021_RS21785	COG1773	rubredoxin
acsn021_RS21785	COG1592	Rubrerythrin
acsn021_RS21790	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
acsn021_RS21795	COG2942	2-epimerase
acsn021_RS21810	COG0513	Belongs to the DEAD box helicase family
acsn021_RS21830	COG1363	Peptidase, m42
acsn021_RS21835	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
acsn021_RS21840	COG0708	Exodeoxyribonuclease III
acsn021_RS21905	COG1131	(ABC) transporter
acsn021_RS21915	COG1357	PFAM Pentapeptide repeats (8 copies)
acsn021_RS21920	COG0745	RESPONSE REGULATOR receiver
acsn021_RS21925	COG5002	protein histidine kinase activity
acsn021_RS21970	COG0789	Transcriptional regulator
acsn021_RS21975	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
acsn021_RS22040	COG0800	Aldolase
acsn021_RS22070	COG0840	transmembrane signaling receptor activity
acsn021_RS22090	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
acsn021_RS22105	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
acsn021_RS22110	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
acsn021_RS22115	COG1827	regulation of RNA biosynthetic process
acsn021_RS22135	COG0166	Belongs to the GPI family
acsn021_RS22160	COG0778	Nitroreductase
acsn021_RS22185	COG0745	RESPONSE REGULATOR receiver
acsn021_RS22190	COG5002	protein histidine kinase activity
acsn021_RS22195	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
acsn021_RS22200	COG3437	response regulator, receiver
acsn021_RS22210	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
acsn021_RS22255	COG0590	tRNA wobble adenosine to inosine editing
acsn021_RS22280	COG3458	cephalosporin-C deacetylase activity
acsn021_RS22295	COG0395	ABC-type sugar transport system, permease component
acsn021_RS22300	COG4209	transmembrane transport
acsn021_RS22305	COG3459	Glycosyltransferase 36 associated
acsn021_RS22320	COG0488	(ABC) transporter
acsn021_RS22330	COG0602	queuosine metabolic process
acsn021_RS22335	COG0205	6-phosphofructokinase activity
acsn021_RS22340	COG3507	Belongs to the glycosyl hydrolase 43 family
acsn021_RS22350	COG0395	ABC-type sugar transport system, permease component
acsn021_RS22355	COG4209	transmembrane transport
acsn021_RS22360	COG0662	Cupin 2, conserved barrel domain protein
acsn021_RS22360	COG2207	Transcriptional regulator
acsn021_RS22380	COG1609	Transcriptional regulator
acsn021_RS22380	COG2207	Transcriptional regulator
acsn021_RS22385	COG2755	lipolytic protein G-D-S-L family
acsn021_RS22390	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
acsn021_RS22395	COG0084	hydrolase, TatD family'
acsn021_RS22410	COG3546	catalase activity
acsn021_RS22430	COG0785	Cytochrome C biogenesis protein
acsn021_RS22450	COG1131	(ABC) transporter
acsn021_RS22455	COG0656	L-ascorbic acid biosynthetic process
acsn021_RS22460	COG0700	Nucleoside recognition
acsn021_RS22465	COG2715	membrane protein required for spore maturation
acsn021_RS22470	COG2002	toxin-antitoxin pair type II binding
acsn021_RS22475	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
acsn021_RS22480	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
acsn021_RS22485	COG1774	PSP1 C-terminal conserved region
acsn021_RS22490	COG0470	DNA polymerase III
acsn021_RS22495	COG1728	Protein conserved in bacteria
acsn021_RS22500	COG0194	GDP metabolic process
acsn021_RS22505	COG1982	Orn Lys Arg decarboxylase major
acsn021_RS22525	COG3279	Response regulator of the LytR AlgR family
acsn021_RS22565	COG0220	tRNA (guanine-N7-)-methyltransferase activity
acsn021_RS22580	COG1269	ATP hydrolysis coupled proton transport
acsn021_RS22610	COG1394	ATPase activity, coupled to movement of substances
acsn021_RS22615	COG1609	Transcriptional regulator
acsn021_RS22620	COG1069	ribulokinase activity
acsn021_RS22630	COG0235	Class ii aldolase
acsn021_RS22635	COG1686	Belongs to the peptidase S11 family
acsn021_RS22660	COG1012	belongs to the aldehyde dehydrogenase family
acsn021_RS22660	COG1454	alcohol dehydrogenase
acsn021_RS22670	COG1475	DNA binding
acsn021_RS22675	COG1192	Involved in chromosome partitioning
acsn021_RS22680	COG2197	response regulator
acsn021_RS22695	COG0357	Ribosomal RNA small subunit methyltransferase G
acsn021_RS22700	COG0445	tRNA wobble uridine modification
acsn021_RS22705	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
acsn021_RS22710	COG1847	R3H domain protein
acsn021_RS22715	COG0706	membrane insertase activity
acsn021_RS22720	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
acsn021_RS22725	COG0594	ribonuclease P activity
acsn021_RS22730	COG0230	Belongs to the bacterial ribosomal protein bL34 family