locus-tag	class	description
bsdcttw_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
bsdcttw_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
bsdcttw_RS00025	COG0187	DNA topoisomerase II activity
bsdcttw_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
bsdcttw_RS00100	COG1902	pentaerythritol trinitrate reductase activity
bsdcttw_RS00105	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
bsdcttw_RS00110	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
bsdcttw_RS00115	COG0745	RESPONSE REGULATOR receiver
bsdcttw_RS00135	COG5002	protein histidine kinase activity
bsdcttw_RS00145	COG1132	(ABC) transporter
bsdcttw_RS00150	COG1132	(ABC) transporter
bsdcttw_RS00160	COG1511	domain protein
bsdcttw_RS00165	COG2357	RelA SpoT domain protein
bsdcttw_RS00170	COG0539	negative regulation of cytoplasmic translation
bsdcttw_RS00195	COG1362	aminopeptidase activity
bsdcttw_RS00215	COG1609	Transcriptional regulator
bsdcttw_RS00225	COG0058	SHG alpha-glucan phosphorylase activity
bsdcttw_RS00235	COG1175	transmembrane transport
bsdcttw_RS00240	COG3833	ABC-type maltose transport systems, permease component
bsdcttw_RS00325	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
bsdcttw_RS00330	COG0457	Tetratricopeptide repeat
bsdcttw_RS00330	COG0705	Rhomboid family
bsdcttw_RS00340	COG3852	Histidine kinase
bsdcttw_RS00345	COG0537	adenosine 5'-monophosphoramidase activity
bsdcttw_RS00350	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
bsdcttw_RS00360	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
bsdcttw_RS00370	COG0166	Belongs to the GPI family
bsdcttw_RS00390	COG1827	regulation of RNA biosynthetic process
bsdcttw_RS00395	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
bsdcttw_RS00400	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
bsdcttw_RS00410	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
bsdcttw_RS00420	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
bsdcttw_RS00425	COG0842	Transport permease protein
bsdcttw_RS00430	COG1131	(ABC) transporter
bsdcttw_RS00435	COG1309	transcriptional regulator
bsdcttw_RS00450	COG2205	protein histidine kinase activity
bsdcttw_RS00450	COG2770	Histidine kinase
bsdcttw_RS00455	COG0745	RESPONSE REGULATOR receiver
bsdcttw_RS00495	COG0800	Aldolase
bsdcttw_RS00530	COG1396	sequence-specific DNA binding
bsdcttw_RS00555	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
bsdcttw_RS00575	COG2207	Transcriptional regulator
bsdcttw_RS00575	COG1917	Cupin 2, conserved barrel domain protein
bsdcttw_RS00600	COG1454	alcohol dehydrogenase
bsdcttw_RS00605	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
bsdcttw_RS00620	COG4209	transmembrane transport
bsdcttw_RS00625	COG0395	ABC-type sugar transport system, permease component
bsdcttw_RS00665	COG4209	transmembrane transport
bsdcttw_RS00670	COG0395	ABC-type sugar transport system, permease component
bsdcttw_RS00680	COG1940	carbohydrate kinase activity
bsdcttw_RS00710	COG1979	alcohol dehydrogenase
bsdcttw_RS00725	COG0288	reversible hydration of carbon dioxide
bsdcttw_RS00745	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
bsdcttw_RS00750	COG1690	Belongs to the RtcB family
bsdcttw_RS00760	COG1028	Short-chain dehydrogenase reductase Sdr
bsdcttw_RS00765	COG0583	DNA-binding transcription factor activity
bsdcttw_RS00770	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
bsdcttw_RS00775	COG1360	Flagellar Motor Protein
bsdcttw_RS00780	COG1070	Carbohydrate kinase
bsdcttw_RS00790	COG0235	Class ii aldolase
bsdcttw_RS00795	COG2407	Converts the aldose L-fucose into the corresponding ketose L-fuculose
bsdcttw_RS00800	COG2207	Transcriptional regulator
bsdcttw_RS00805	COG0443	Heat shock 70 kDa protein
bsdcttw_RS00815	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
bsdcttw_RS00835	COG1733	regulation of RNA biosynthetic process
bsdcttw_RS00840	COG2207	Transcriptional regulator
bsdcttw_RS00845	COG2972	Histidine kinase
bsdcttw_RS00875	COG2207	Transcriptional regulator
bsdcttw_RS00880	COG1653	transport
bsdcttw_RS00885	COG4209	transmembrane transport
bsdcttw_RS00890	COG0395	ABC-type sugar transport system, permease component
bsdcttw_RS00930	COG3620	sequence-specific DNA binding
bsdcttw_RS00935	COG1917	Cupin 2, conserved barrel domain protein
bsdcttw_RS00935	COG4977	sequence-specific DNA binding
bsdcttw_RS01030	COG0789	Transcriptional regulator
bsdcttw_RS01035	COG0477	Major facilitator Superfamily
bsdcttw_RS01090	COG1105	Belongs to the carbohydrate kinase PfkB family
bsdcttw_RS01095	COG2222	sugar isomerase
bsdcttw_RS01100	COG1288	antiporter activity
bsdcttw_RS01105	COG1082	Xylose isomerase domain protein TIM barrel
bsdcttw_RS01110	COG1228	amidohydrolase
bsdcttw_RS01115	COG2188	Transcriptional regulator
bsdcttw_RS01125	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
bsdcttw_RS01150	COG0708	Exodeoxyribonuclease III
bsdcttw_RS01160	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
bsdcttw_RS01165	COG1363	Peptidase, m42
bsdcttw_RS01175	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
bsdcttw_RS01185	COG0745	RESPONSE REGULATOR receiver
bsdcttw_RS01200	COG2205	protein histidine kinase activity
bsdcttw_RS01215	COG0513	Belongs to the DEAD box helicase family
bsdcttw_RS01220	COG2942	2-epimerase
bsdcttw_RS01225	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
bsdcttw_RS01235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
bsdcttw_RS01240	COG3576	pyridoxamine 5-phosphate
bsdcttw_RS01250	COG1773	rubredoxin
bsdcttw_RS01250	COG1592	Rubrerythrin
bsdcttw_RS01255	COG0735	belongs to the Fur family
bsdcttw_RS01265	COG4481	Protein conserved in bacteria
bsdcttw_RS01270	COG1940	carbohydrate kinase activity
bsdcttw_RS01295	COG0360	Binds together with S18 to 16S ribosomal RNA
bsdcttw_RS01300	COG0629	single-stranded DNA binding
bsdcttw_RS01305	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
bsdcttw_RS01335	COG3142	Participates in the control of copper homeostasis
bsdcttw_RS01350	COG4209	transmembrane transport
bsdcttw_RS01355	COG0395	ABC-type sugar transport system, permease component
bsdcttw_RS01360	COG1653	transport
bsdcttw_RS01375	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
bsdcttw_RS01385	COG0561	phosphatase activity
bsdcttw_RS01390	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
bsdcttw_RS01400	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
bsdcttw_RS01405	COG0573	inorganic phosphate transmembrane transporter activity
bsdcttw_RS01410	COG0581	inorganic phosphate transmembrane transporter activity
bsdcttw_RS01415	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
bsdcttw_RS01435	COG1132	(ABC) transporter
bsdcttw_RS01445	COG0028	Belongs to the TPP enzyme family
bsdcttw_RS01450	COG1028	Short-chain dehydrogenase reductase Sdr
bsdcttw_RS01465	COG0450	alkyl hydroperoxide reductase
bsdcttw_RS01500	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
bsdcttw_RS01530	COG2814	Major facilitator Superfamily
bsdcttw_RS01540	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
bsdcttw_RS01545	COG0359	binds to the 23S rRNA
bsdcttw_RS01550	COG0305	Participates in initiation and elongation during chromosome replication
bsdcttw_RS01555	COG0789	Transcriptional regulator
bsdcttw_RS01575	COG0515	serine threonine protein kinase
bsdcttw_RS01590	COG0860	N-Acetylmuramoyl-L-alanine amidase
bsdcttw_RS01595	COG0009	L-threonylcarbamoyladenylate synthase
bsdcttw_RS01600	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
bsdcttw_RS01605	COG0698	ribose 5-phosphate isomerase
bsdcttw_RS01630	COG1216	Glycosyl transferase, family 2
bsdcttw_RS01640	COG1490	D-aminoacyl-tRNA deacylase activity
bsdcttw_RS01660	COG1609	Transcriptional regulator
bsdcttw_RS01670	COG1609	Transcriptional regulator
bsdcttw_RS01685	COG0598	Magnesium transport protein CorA
bsdcttw_RS01690	COG2252	PERMEase
bsdcttw_RS01710	COG1609	Transcriptional regulator
bsdcttw_RS01715	COG1252	NADH dehydrogenase
bsdcttw_RS01745	COG1609	Transcriptional regulator
bsdcttw_RS01750	COG0267	Belongs to the bacterial ribosomal protein bL33 family
bsdcttw_RS01760	COG0250	Participates in transcription elongation, termination and antitermination
bsdcttw_RS01765	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
bsdcttw_RS01770	COG0081	regulation of translation
bsdcttw_RS01780	COG0222	ribosome binding
bsdcttw_RS01785	COG0085	RNA polymerase activity
bsdcttw_RS01790	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
bsdcttw_RS01800	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
bsdcttw_RS01805	COG0049	tRNA binding
bsdcttw_RS01810	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
bsdcttw_RS01815	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
bsdcttw_RS01820	COG0588	phosphoglycerate mutase activity
bsdcttw_RS01825	COG5001	Diguanylate cyclase
bsdcttw_RS01825	COG3300	MHYT domain
bsdcttw_RS01835	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
bsdcttw_RS01845	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
bsdcttw_RS01850	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
bsdcttw_RS01880	COG1077	Cell shape determining protein MreB Mrl
bsdcttw_RS01885	COG4786	Flagellar basal body rod
bsdcttw_RS01900	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
bsdcttw_RS01905	COG1040	competence protein
bsdcttw_RS01915	COG2996	Protein conserved in bacteria
bsdcttw_RS01925	COG0251	oxidation-reduction process
bsdcttw_RS01945	COG0791	NLP P60 protein
bsdcttw_RS01955	COG0653	protein targeting
bsdcttw_RS01970	COG4492	Belongs to the UPF0735 family
bsdcttw_RS01975	COG0460	homoserine dehydrogenase
bsdcttw_RS01980	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
bsdcttw_RS01990	COG2116	formate transmembrane transporter activity
bsdcttw_RS02040	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
bsdcttw_RS02055	COG0438	transferase activity, transferring glycosyl groups
bsdcttw_RS02080	COG2244	polysaccharide biosynthetic process
bsdcttw_RS02095	COG3290	protein histidine kinase activity
bsdcttw_RS02095	COG0840	transmembrane signaling receptor activity
bsdcttw_RS02105	COG2183	response to ionizing radiation
bsdcttw_RS02115	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
bsdcttw_RS02120	COG4464	protein tyrosine phosphatase activity
bsdcttw_RS02140	COG4464	protein tyrosine phosphatase activity
bsdcttw_RS02175	COG1132	(ABC) transporter
bsdcttw_RS02185	COG1316	TRANSCRIPTIONal
bsdcttw_RS02195	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
bsdcttw_RS02200	COG0802	atpase or kinase
bsdcttw_RS02205	COG1214	PFAM Peptidase M22, glycoprotease
bsdcttw_RS02210	COG0456	acetyltransferase
bsdcttw_RS02220	COG1234	tRNA 3'-trailer cleavage
bsdcttw_RS02230	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
bsdcttw_RS02320	COG0840	transmembrane signaling receptor activity
bsdcttw_RS02325	COG0582	viral genome integration into host DNA
bsdcttw_RS02340	COG0116	Belongs to the methyltransferase superfamily
bsdcttw_RS02345	COG0789	Transcriptional regulator
bsdcttw_RS02350	COG1132	(ABC) transporter
bsdcttw_RS02355	COG0860	N-Acetylmuramoyl-L-alanine amidase
bsdcttw_RS02360	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
bsdcttw_RS02410	COG1216	Glycosyl transferase, family 2
bsdcttw_RS02415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
bsdcttw_RS02425	COG3845	ABC transporter
bsdcttw_RS02430	COG4603	Belongs to the binding-protein-dependent transport system permease family
bsdcttw_RS02435	COG1079	Belongs to the binding-protein-dependent transport system permease family
bsdcttw_RS02455	COG1115	amino acid carrier protein
bsdcttw_RS02465	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
bsdcttw_RS02470	COG0544	peptidyl-prolyl cis-trans isomerase activity
bsdcttw_RS02480	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
bsdcttw_RS02485	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
bsdcttw_RS02490	COG0218	Necessary for normal cell division and for the maintenance of normal septation
bsdcttw_RS02500	COG1242	4 iron, 4 sulfur cluster binding
bsdcttw_RS02505	COG0281	malic enzyme
bsdcttw_RS02510	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
bsdcttw_RS02515	COG0254	rRNA binding
bsdcttw_RS02520	COG3872	metal-dependent enzyme
bsdcttw_RS02530	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
bsdcttw_RS02550	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
bsdcttw_RS02555	COG2197	response regulator
bsdcttw_RS02565	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
bsdcttw_RS02585	COG1368	sulfuric ester hydrolase activity
bsdcttw_RS02595	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
bsdcttw_RS02620	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
bsdcttw_RS02625	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
bsdcttw_RS02635	COG3708	Transcriptional regulator
bsdcttw_RS02635	COG2207	Transcriptional regulator
bsdcttw_RS02650	COG3459	Glycosyltransferase 36 associated
bsdcttw_RS02665	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
bsdcttw_RS02685	COG1671	Belongs to the UPF0178 family
bsdcttw_RS02695	COG1132	(ABC) transporter
bsdcttw_RS02700	COG1132	(ABC) transporter
bsdcttw_RS02710	COG1940	carbohydrate kinase activity
bsdcttw_RS02715	COG0673	inositol 2-dehydrogenase activity
bsdcttw_RS02735	COG2340	Cysteine-rich secretory protein family
bsdcttw_RS02745	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
bsdcttw_RS02750	COG0840	transmembrane signaling receptor activity
bsdcttw_RS02845	COG2972	Histidine kinase
bsdcttw_RS02850	COG4753	response regulator
bsdcttw_RS02850	COG2207	Transcriptional regulator
bsdcttw_RS02865	COG1796	DNA polymerase
bsdcttw_RS02865	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
bsdcttw_RS02870	COG4209	transmembrane transport
bsdcttw_RS02880	COG0395	ABC-type sugar transport system, permease component
bsdcttw_RS02885	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
bsdcttw_RS02890	COG1486	melibiose metabolic process
bsdcttw_RS02960	COG1131	(ABC) transporter
bsdcttw_RS02975	COG0232	Belongs to the dGTPase family. Type 2 subfamily
bsdcttw_RS02980	COG3507	Belongs to the glycosyl hydrolase 43 family
bsdcttw_RS02990	COG3250	beta-galactosidase activity
bsdcttw_RS03020	COG1175	transmembrane transport
bsdcttw_RS03025	COG0395	ABC-type sugar transport system, permease component
bsdcttw_RS03050	COG2201	protein-glutamate methylesterase activity
bsdcttw_RS03055	COG0643	Histidine kinase
bsdcttw_RS03055	COG2198	Histidine kinase
bsdcttw_RS03060	COG2198	Histidine kinase
bsdcttw_RS03060	COG0784	Response regulator, receiver
bsdcttw_RS03060	COG5002	protein histidine kinase activity
bsdcttw_RS03065	COG0745	RESPONSE REGULATOR receiver
bsdcttw_RS03070	COG0835	chemotaxis
bsdcttw_RS03075	COG0840	transmembrane signaling receptor activity
bsdcttw_RS03085	COG2201	protein-glutamate methylesterase activity
bsdcttw_RS03100	COG1595	DNA-templated transcription, initiation
bsdcttw_RS03115	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
bsdcttw_RS03115	COG2111	Na H antiporter
bsdcttw_RS03120	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
bsdcttw_RS03125	COG3260	NADH ubiquinone oxidoreductase 20
bsdcttw_RS03135	COG0649	NAD binding
bsdcttw_RS03155	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
bsdcttw_RS03160	COG0298	carbon dioxide binding
bsdcttw_RS03175	COG1929	Belongs to the glycerate kinase type-1 family
bsdcttw_RS03185	COG0673	inositol 2-dehydrogenase activity
bsdcttw_RS03190	COG0673	inositol 2-dehydrogenase activity
bsdcttw_RS03205	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
bsdcttw_RS03210	COG3307	-O-antigen
bsdcttw_RS03220	COG1278	Cold shock
bsdcttw_RS03230	COG0674	pyruvate-flavodoxin oxidoreductase activity
bsdcttw_RS03230	COG1013	pyruvate-flavodoxin oxidoreductase activity
bsdcttw_RS03230	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
bsdcttw_RS03230	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
bsdcttw_RS03235	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
bsdcttw_RS03240	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
bsdcttw_RS03340	COG3279	Response regulator of the LytR AlgR family
bsdcttw_RS03365	COG1472	Belongs to the glycosyl hydrolase 3 family
bsdcttw_RS03375	COG0463	Glycosyl transferase, family 2
bsdcttw_RS03385	COG0347	Belongs to the P(II) protein family
bsdcttw_RS03455	COG4149	molybdate abc transporter
bsdcttw_RS03475	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
bsdcttw_RS03490	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
bsdcttw_RS03495	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
bsdcttw_RS03500	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
bsdcttw_RS03515	COG1316	TRANSCRIPTIONal
bsdcttw_RS03525	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
bsdcttw_RS03535	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
bsdcttw_RS03575	COG0436	Aminotransferase
bsdcttw_RS03600	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
bsdcttw_RS03605	COG0459	protein refolding
bsdcttw_RS03615	COG0517	IMP dehydrogenase activity
bsdcttw_RS03615	COG0516	GMP reductase activity
bsdcttw_RS03635	COG0573	inorganic phosphate transmembrane transporter activity
bsdcttw_RS03640	COG0581	inorganic phosphate transmembrane transporter activity
bsdcttw_RS03645	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
bsdcttw_RS03650	COG0704	Plays a role in the regulation of phosphate uptake
bsdcttw_RS03655	COG0745	RESPONSE REGULATOR receiver
bsdcttw_RS03660	COG5002	protein histidine kinase activity
bsdcttw_RS03675	COG0138	bifunctional purine biosynthesis protein purh
bsdcttw_RS03695	COG2169	Transcriptional regulator
bsdcttw_RS03705	COG0488	(ABC) transporter
bsdcttw_RS03715	COG2268	Band 7 protein
bsdcttw_RS03725	COG0745	RESPONSE REGULATOR receiver
bsdcttw_RS03730	COG5002	protein histidine kinase activity
bsdcttw_RS03730	COG3850	Histidine kinase
bsdcttw_RS03740	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
bsdcttw_RS03740	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
bsdcttw_RS03745	COG1307	EDD domain protein, DegV family
bsdcttw_RS03755	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
bsdcttw_RS03760	COG1074	ATP-dependent DNA helicase activity
bsdcttw_RS03765	COG0840	transmembrane signaling receptor activity
bsdcttw_RS03790	COG1070	Carbohydrate kinase
bsdcttw_RS03805	COG1131	(ABC) transporter
bsdcttw_RS03815	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
bsdcttw_RS03820	COG2226	methyltransferase
bsdcttw_RS03825	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
bsdcttw_RS03840	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
bsdcttw_RS03845	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
bsdcttw_RS03850	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
bsdcttw_RS03855	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
bsdcttw_RS03855	COG4447	cellulose binding
bsdcttw_RS03860	COG2388	GCN5-related N-acetyl-transferase
bsdcttw_RS03875	COG0756	dUTP diphosphatase activity
bsdcttw_RS03880	COG1683	Conserved Protein
bsdcttw_RS03900	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
bsdcttw_RS03905	COG1621	beta-fructofuranosidase activity
bsdcttw_RS03940	COG0525	valine-tRNA ligase activity
bsdcttw_RS03955	COG1366	Belongs to the anti-sigma-factor antagonist family
bsdcttw_RS04010	COG1739	Uncharacterized protein family UPF0029
bsdcttw_RS04020	COG0004	ammonium transporteR
bsdcttw_RS04030	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
bsdcttw_RS04040	COG0004	ammonium transporteR
bsdcttw_RS04045	COG0347	Belongs to the P(II) protein family
bsdcttw_RS04065	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
bsdcttw_RS04070	COG1404	Belongs to the peptidase S8 family
bsdcttw_RS04075	COG2267	carboxylic ester hydrolase activity
bsdcttw_RS04080	COG1404	Belongs to the peptidase S8 family
bsdcttw_RS04120	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
bsdcttw_RS04145	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
bsdcttw_RS04155	COG0456	acetyltransferase
bsdcttw_RS04160	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
bsdcttw_RS04205	COG0798	PFAM Bile acid sodium symporter
bsdcttw_RS04215	COG0464	growth
bsdcttw_RS04235	COG0653	protein targeting
bsdcttw_RS04255	COG1125	glycine betaine transport
bsdcttw_RS04255	COG0517	IMP dehydrogenase activity
bsdcttw_RS04260	COG1174	glycine betaine transport
bsdcttw_RS04270	COG0840	transmembrane signaling receptor activity
bsdcttw_RS04300	COG2070	2-Nitropropane dioxygenase
bsdcttw_RS04305	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
bsdcttw_RS04310	COG1028	Short-chain dehydrogenase reductase Sdr
bsdcttw_RS04315	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
bsdcttw_RS04320	COG0511	ligase activity, forming carbon-carbon bonds
bsdcttw_RS04330	COG0439	Biotin carboxylase
bsdcttw_RS04335	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
bsdcttw_RS04340	COG0825	malonyl-CoA metabolic process
bsdcttw_RS04350	COG2261	transglycosylase associated protein
bsdcttw_RS04355	COG0372	Belongs to the citrate synthase family
bsdcttw_RS04360	COG1803	Methylglyoxal synthase
bsdcttw_RS04365	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
bsdcttw_RS04375	COG1592	Rubrerythrin
bsdcttw_RS04380	COG2033	superoxide reductase activity
bsdcttw_RS04385	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
bsdcttw_RS04395	COG0426	domain, Protein
bsdcttw_RS04395	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
bsdcttw_RS04410	COG0741	lytic transglycosylase activity
bsdcttw_RS04425	COG2213	PTS system mannitol-specific
bsdcttw_RS04425	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
bsdcttw_RS04430	COG3711	transcriptional antiterminator
bsdcttw_RS04435	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
bsdcttw_RS04435	COG2213	PTS system mannitol-specific
bsdcttw_RS04440	COG1105	Belongs to the carbohydrate kinase PfkB family
bsdcttw_RS04445	COG1063	alcohol dehydrogenase
bsdcttw_RS04455	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
bsdcttw_RS04460	COG2706	6-phosphogluconolactonase activity
bsdcttw_RS04470	COG0840	transmembrane signaling receptor activity
bsdcttw_RS04490	COG2972	Histidine kinase
bsdcttw_RS04500	COG1175	transmembrane transport
bsdcttw_RS04505	COG0395	ABC-type sugar transport system, permease component
bsdcttw_RS04510	COG2207	Transcriptional regulator
bsdcttw_RS04510	COG4753	response regulator
bsdcttw_RS04525	COG3118	belongs to the thioredoxin family
bsdcttw_RS04590	COG3250	beta-galactosidase activity
bsdcttw_RS04595	COG4209	transmembrane transport
bsdcttw_RS04600	COG0395	ABC-type sugar transport system, permease component
bsdcttw_RS04620	COG4565	transcriptional regulatory protein
bsdcttw_RS04625	COG2972	Histidine kinase
bsdcttw_RS04645	COG3250	beta-galactosidase activity
bsdcttw_RS04655	COG0312	modulator of DNA gyrase
bsdcttw_RS04665	COG1191	sigma factor activity
bsdcttw_RS04690	COG1691	(AIR) carboxylase
bsdcttw_RS04695	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
bsdcttw_RS04700	COG2203	Gaf domain
bsdcttw_RS04700	COG3706	GGDEF domain
bsdcttw_RS04700	COG4251	negative regulation of phosphorylation
bsdcttw_RS04700	COG5001	Diguanylate cyclase
bsdcttw_RS04710	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
bsdcttw_RS04715	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
bsdcttw_RS04720	COG1116	anion transmembrane transporter activity
bsdcttw_RS04725	COG0628	permease
bsdcttw_RS04740	COG1217	gtp-binding protein TYPA
bsdcttw_RS04755	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
bsdcttw_RS04760	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
bsdcttw_RS04765	COG1131	(ABC) transporter
bsdcttw_RS04785	COG2207	Transcriptional regulator
bsdcttw_RS04795	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
bsdcttw_RS04810	COG0673	inositol 2-dehydrogenase activity
bsdcttw_RS04820	COG0673	inositol 2-dehydrogenase activity
bsdcttw_RS04840	COG4977	sequence-specific DNA binding
bsdcttw_RS04840	COG1917	Cupin 2, conserved barrel domain protein
bsdcttw_RS04855	COG1070	Carbohydrate kinase
bsdcttw_RS04860	COG2972	Histidine kinase
bsdcttw_RS04875	COG4209	transmembrane transport
bsdcttw_RS04880	COG0395	ABC-type sugar transport system, permease component
bsdcttw_RS04895	COG2972	Histidine kinase
bsdcttw_RS04900	COG0745	RESPONSE REGULATOR receiver
bsdcttw_RS04910	COG4209	transmembrane transport
bsdcttw_RS04915	COG3833	ABC-type maltose transport systems, permease component
bsdcttw_RS04920	COG1472	Belongs to the glycosyl hydrolase 3 family
bsdcttw_RS04945	COG3275	phosphorelay sensor kinase activity
bsdcttw_RS04955	COG1653	transport
bsdcttw_RS04960	COG4209	transmembrane transport
bsdcttw_RS04965	COG0395	ABC-type sugar transport system, permease component
bsdcttw_RS04980	COG2247	cell wall binding repeat
bsdcttw_RS04980	COG2385	sporulation resulting in formation of a cellular spore
bsdcttw_RS05000	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
bsdcttw_RS05005	COG0072	phenylalanine-tRNA ligase activity
bsdcttw_RS05005	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
bsdcttw_RS05035	COG3853	Toxic anion resistance protein (TelA)
bsdcttw_RS05040	COG0745	RESPONSE REGULATOR receiver
bsdcttw_RS05045	COG5002	protein histidine kinase activity
bsdcttw_RS05055	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
bsdcttw_RS05060	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
bsdcttw_RS05065	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
bsdcttw_RS05070	COG0151	Belongs to the GarS family
bsdcttw_RS05090	COG3880	PFAM UvrB UvrC protein
bsdcttw_RS05095	COG3869	Catalyzes the specific phosphorylation of arginine residues in
bsdcttw_RS05100	COG0542	response to heat
bsdcttw_RS05110	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
bsdcttw_RS05125	COG1592	Rubrerythrin
bsdcttw_RS05160	COG0343	queuine tRNA-ribosyltransferase activity
bsdcttw_RS05165	COG1862	Preprotein translocase
bsdcttw_RS05170	COG0613	PHP domain protein
bsdcttw_RS05185	COG0820	rRNA (adenine-C2-)-methyltransferase activity
bsdcttw_RS05190	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
bsdcttw_RS05190	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
bsdcttw_RS05200	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
bsdcttw_RS05205	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
bsdcttw_RS05210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
bsdcttw_RS05215	COG0635	Involved in the biosynthesis of porphyrin-containing compound
bsdcttw_RS05225	COG1362	aminopeptidase activity
bsdcttw_RS05235	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
bsdcttw_RS05245	COG1395	domain, Protein
bsdcttw_RS05270	COG2017	converts alpha-aldose to the beta-anomer
bsdcttw_RS05275	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
bsdcttw_RS05290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
bsdcttw_RS05295	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
bsdcttw_RS05300	COG1120	ATPase activity
bsdcttw_RS05315	COG3655	Transcriptional regulator
bsdcttw_RS05320	COG1032	radical SAM domain protein
bsdcttw_RS05330	COG0723	plastoquinol--plastocyanin reductase activity
bsdcttw_RS05330	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
bsdcttw_RS05340	COG4377	Putative membrane peptidase family (DUF2324)
bsdcttw_RS05345	COG3290	protein histidine kinase activity
bsdcttw_RS05365	COG1131	(ABC) transporter
bsdcttw_RS05380	COG0148	phosphopyruvate hydratase activity
bsdcttw_RS05390	COG3764	Sortase (surface protein transpeptidase)
bsdcttw_RS05415	COG2755	lipolytic protein G-D-S-L family
bsdcttw_RS05420	COG1609	Transcriptional regulator
bsdcttw_RS05425	COG0395	ABC-type sugar transport system, permease component
bsdcttw_RS05435	COG1175	transmembrane transport
bsdcttw_RS05460	COG3408	Glycogen debranching enzyme
bsdcttw_RS05475	COG2124	cytochrome p450
bsdcttw_RS05495	COG0563	adenylate kinase activity
bsdcttw_RS05525	COG1082	Xylose isomerase domain protein TIM barrel
bsdcttw_RS05590	COG1132	(ABC) transporter
bsdcttw_RS05595	COG0534	Mate efflux family protein
bsdcttw_RS05610	COG0248	Ppx GppA phosphatase
bsdcttw_RS05615	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
bsdcttw_RS05640	COG0662	Cupin 2, conserved barrel domain protein
bsdcttw_RS05640	COG2207	Transcriptional regulator
bsdcttw_RS05645	COG1082	Xylose isomerase domain protein TIM barrel
bsdcttw_RS05650	COG0673	inositol 2-dehydrogenase activity
bsdcttw_RS05665	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
bsdcttw_RS05670	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
bsdcttw_RS05670	COG1328	CTP reductase activity
bsdcttw_RS05675	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
bsdcttw_RS05680	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
bsdcttw_RS05685	COG1307	EDD domain protein, DegV family
bsdcttw_RS05690	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
bsdcttw_RS05695	COG1285	pathogenesis
bsdcttw_RS05700	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
bsdcttw_RS05725	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
bsdcttw_RS05735	COG4608	Belongs to the ABC transporter superfamily
bsdcttw_RS05775	COG2002	toxin-antitoxin pair type II binding
bsdcttw_RS05795	COG3935	DnaD domain protein
bsdcttw_RS05845	COG0582	viral genome integration into host DNA
bsdcttw_RS05875	COG0740	serine-type endopeptidase activity
bsdcttw_RS05995	COG4824	toxin secretion phage lysis holin
bsdcttw_RS06000	COG1705	Flagellar rod assembly protein muramidase FlgJ
bsdcttw_RS06055	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
bsdcttw_RS06060	COG4935	Belongs to the peptidase S8 family
bsdcttw_RS06060	COG1404	Belongs to the peptidase S8 family
bsdcttw_RS06100	COG0583	DNA-binding transcription factor activity
bsdcttw_RS06125	COG1528	Iron-storage protein
bsdcttw_RS06130	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
bsdcttw_RS06155	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
bsdcttw_RS06170	COG0387	Pfam Sodium calcium exchanger
bsdcttw_RS06175	COG1609	Transcriptional regulator
bsdcttw_RS06185	COG3959	Transketolase, thiamine diphosphate binding domain
bsdcttw_RS06190	COG3958	Transketolase
bsdcttw_RS06195	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
bsdcttw_RS06200	COG2207	Transcriptional regulator
bsdcttw_RS06200	COG4753	response regulator
bsdcttw_RS06205	COG3275	phosphorelay sensor kinase activity
bsdcttw_RS06215	COG4209	transmembrane transport
bsdcttw_RS06220	COG0395	ABC-type sugar transport system, permease component
bsdcttw_RS06225	COG0534	Mate efflux family protein
bsdcttw_RS06235	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
bsdcttw_RS06245	COG0531	amino acid
bsdcttw_RS06250	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
bsdcttw_RS06270	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
bsdcttw_RS06295	COG0436	Aminotransferase
bsdcttw_RS06310	COG0017	Asparaginyl-tRNA synthetase
bsdcttw_RS06315	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
bsdcttw_RS06320	COG0154	amidase activity
bsdcttw_RS06325	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
bsdcttw_RS06340	COG0070	glutamate synthase
bsdcttw_RS06340	COG0069	glutamate synthase activity
bsdcttw_RS06340	COG0067	glutamate synthase
bsdcttw_RS06345	COG0493	'glutamate synthase
bsdcttw_RS06360	COG2267	carboxylic ester hydrolase activity
bsdcttw_RS06365	COG1312	Catalyzes the dehydration of D-mannonate
bsdcttw_RS06370	COG1472	Belongs to the glycosyl hydrolase 3 family
bsdcttw_RS06385	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
bsdcttw_RS06390	COG0504	CTP synthase activity
bsdcttw_RS06395	COG1307	EDD domain protein, DegV family
bsdcttw_RS06400	COG5297	Belongs to the glycosyl hydrolase family 6
bsdcttw_RS06400	COG4447	cellulose binding
bsdcttw_RS06420	COG3209	COG3209 Rhs family protein
bsdcttw_RS06450	COG1609	Transcriptional regulator
bsdcttw_RS06455	COG4209	transmembrane transport
bsdcttw_RS06460	COG0395	ABC-type sugar transport system, permease component
bsdcttw_RS06470	COG1621	beta-fructofuranosidase activity
bsdcttw_RS06485	COG1609	Transcriptional regulator
bsdcttw_RS06490	COG1686	Belongs to the peptidase S11 family
bsdcttw_RS06500	COG3976	FMN-binding domain protein
bsdcttw_RS06500	COG1053	succinate dehydrogenase
bsdcttw_RS06505	COG0551	DNA topoisomerase type I activity
bsdcttw_RS06505	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
bsdcttw_RS06515	COG1956	GAF domain-containing protein
bsdcttw_RS06535	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
bsdcttw_RS06540	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
bsdcttw_RS06545	COG1649	PFAM Uncharacterised BCR, COG1649
bsdcttw_RS06545	COG0726	polysaccharide deacetylase
bsdcttw_RS06550	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
bsdcttw_RS06550	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
bsdcttw_RS06565	COG0523	cobalamin synthesis protein
bsdcttw_RS06570	COG0701	Predicted permease
bsdcttw_RS06580	COG0267	Belongs to the bacterial ribosomal protein bL33 family
bsdcttw_RS06585	COG0803	Belongs to the bacterial solute-binding protein 9 family
bsdcttw_RS06590	COG1121	(ABC) transporter
bsdcttw_RS06595	COG1108	ABC-type Mn2 Zn2 transport systems permease components
bsdcttw_RS06615	COG2207	Transcriptional regulator
bsdcttw_RS06620	COG4209	transmembrane transport
bsdcttw_RS06625	COG0395	ABC-type sugar transport system, permease component
bsdcttw_RS06630	COG1653	transport
bsdcttw_RS06635	COG0840	transmembrane signaling receptor activity
bsdcttw_RS06650	COG2207	Transcriptional regulator
bsdcttw_RS06670	COG5566	PFAM Mor transcription activator
bsdcttw_RS06675	COG2326	polyphosphate kinase activity
bsdcttw_RS06680	COG0840	transmembrane signaling receptor activity
bsdcttw_RS06685	COG0840	transmembrane signaling receptor activity
bsdcttw_RS06695	COG0789	Transcriptional regulator
bsdcttw_RS06705	COG1331	Highly conserved protein containing a thioredoxin domain
bsdcttw_RS06710	COG2094	Belongs to the DNA glycosylase MPG family
bsdcttw_RS06730	COG2972	Histidine kinase
bsdcttw_RS06735	COG2207	Transcriptional regulator
bsdcttw_RS06735	COG4753	response regulator
bsdcttw_RS06745	COG1175	transmembrane transport
bsdcttw_RS06750	COG0395	ABC-type sugar transport system, permease component
bsdcttw_RS06765	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
bsdcttw_RS06775	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
bsdcttw_RS06780	COG1396	sequence-specific DNA binding
bsdcttw_RS06795	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
bsdcttw_RS06820	COG4948	Mandelate Racemase Muconate Lactonizing
bsdcttw_RS06830	COG0277	FAD linked oxidase domain protein
bsdcttw_RS06835	COG2972	Histidine kinase
bsdcttw_RS06840	COG2197	response regulator
bsdcttw_RS06845	COG1653	transport
bsdcttw_RS06860	COG1696	Membrane protein involved in D-alanine export
bsdcttw_RS06935	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
bsdcttw_RS06940	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
bsdcttw_RS06945	COG2205	protein histidine kinase activity
bsdcttw_RS06950	COG0745	RESPONSE REGULATOR receiver
bsdcttw_RS06970	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
bsdcttw_RS06970	COG0646	methionine synthase
bsdcttw_RS06980	COG0646	methionine synthase
bsdcttw_RS06980	COG1410	methionine synthase
bsdcttw_RS06985	COG1846	Transcriptional regulator
bsdcttw_RS07015	COG0789	Transcriptional regulator
bsdcttw_RS07025	COG0534	Mate efflux family protein
bsdcttw_RS07030	COG0739	heme binding
bsdcttw_RS07035	COG1595	DNA-templated transcription, initiation
bsdcttw_RS07045	COG4977	sequence-specific DNA binding
bsdcttw_RS07075	COG0367	asparagine synthase
bsdcttw_RS07130	COG4209	transmembrane transport
bsdcttw_RS07135	COG0395	ABC-type sugar transport system, permease component
bsdcttw_RS07140	COG1653	transport
bsdcttw_RS07145	COG0445	tRNA wobble uridine modification
bsdcttw_RS07165	COG3459	Glycosyltransferase 36 associated
bsdcttw_RS07170	COG2207	Transcriptional regulator
bsdcttw_RS07170	COG4753	response regulator
bsdcttw_RS07185	COG0277	FAD linked oxidase domain protein
bsdcttw_RS07195	COG5632	N-Acetylmuramoyl-L-alanine amidase
bsdcttw_RS07195	COG3409	Peptidoglycan-binding domain 1 protein
bsdcttw_RS07200	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
bsdcttw_RS07220	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
bsdcttw_RS07235	COG1192	Involved in chromosome partitioning
bsdcttw_RS07240	COG1475	DNA binding
bsdcttw_RS07415	COG2003	Belongs to the UPF0758 family
bsdcttw_RS07420	COG0629	single-stranded DNA binding
bsdcttw_RS07510	COG2132	Multicopper oxidase
bsdcttw_RS07550	COG5002	protein histidine kinase activity
bsdcttw_RS07555	COG2204	response regulator
bsdcttw_RS07570	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
bsdcttw_RS07585	COG3852	Histidine kinase
bsdcttw_RS07600	COG2217	Heavy metal translocating P-type atpase
bsdcttw_RS07605	COG2608	mercury ion transmembrane transporter activity
bsdcttw_RS07615	COG2226	methyltransferase
bsdcttw_RS07640	COG0653	protein targeting
bsdcttw_RS07670	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
bsdcttw_RS07685	COG1846	Transcriptional regulator
bsdcttw_RS07690	COG2226	methyltransferase
bsdcttw_RS07700	COG0640	Transcriptional regulator
bsdcttw_RS07720	COG0390	transport system, permease component
bsdcttw_RS07725	COG4619	ABC transporter
bsdcttw_RS07735	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
bsdcttw_RS07740	COG2207	Transcriptional regulator
bsdcttw_RS07740	COG1917	Cupin 2, conserved barrel domain protein
bsdcttw_RS07770	COG1028	Short-chain dehydrogenase reductase Sdr
bsdcttw_RS07780	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
bsdcttw_RS07805	COG4496	protein, YerC YecD
bsdcttw_RS07820	COG0446	pyridine nucleotide-disulphide oxidoreductase
bsdcttw_RS07830	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
bsdcttw_RS07840	COG0644	oxidoreductase
bsdcttw_RS07850	COG1917	Cupin 2, conserved barrel domain protein
bsdcttw_RS07850	COG2207	Transcriptional regulator
bsdcttw_RS07870	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
bsdcttw_RS07870	COG2508	Transcriptional regulator
bsdcttw_RS07880	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
bsdcttw_RS07885	COG0655	NAD(P)H dehydrogenase (quinone) activity
bsdcttw_RS07900	COG1309	transcriptional regulator
bsdcttw_RS07905	COG3321	synthase
bsdcttw_RS07905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
bsdcttw_RS07905	COG0604	alcohol dehydrogenase
bsdcttw_RS07905	COG4221	oxidoreductase activity
bsdcttw_RS07910	COG1309	transcriptional regulator
bsdcttw_RS07960	COG0693	protein deglycase activity
bsdcttw_RS07975	COG4716	Myosin-crossreactive antigen
bsdcttw_RS07980	COG0820	rRNA (adenine-C2-)-methyltransferase activity
bsdcttw_RS07995	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
bsdcttw_RS08030	COG0583	DNA-binding transcription factor activity
bsdcttw_RS08035	COG1053	succinate dehydrogenase
bsdcttw_RS08035	COG0431	NADPH-dependent FMN reductase
bsdcttw_RS08035	COG3976	FMN-binding domain protein
bsdcttw_RS08045	COG0277	FAD linked oxidase domain protein
bsdcttw_RS08055	COG1309	transcriptional regulator
bsdcttw_RS08075	COG2207	Transcriptional regulator
bsdcttw_RS08085	COG0583	DNA-binding transcription factor activity
bsdcttw_RS08095	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
bsdcttw_RS08105	COG0412	Dienelactone hydrolase
bsdcttw_RS08115	COG1404	Belongs to the peptidase S8 family
bsdcttw_RS08120	COG4989	oxidoreductase activity
bsdcttw_RS08125	COG1573	uracil-dna glycosylase
bsdcttw_RS08135	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
bsdcttw_RS08150	COG5002	protein histidine kinase activity
bsdcttw_RS08165	COG5002	protein histidine kinase activity
bsdcttw_RS08175	COG0577	efflux transmembrane transporter activity
bsdcttw_RS08180	COG1136	(ABC) transporter
bsdcttw_RS08195	COG0840	transmembrane signaling receptor activity
bsdcttw_RS08195	COG5278	phosphoserine phosphatase activity
bsdcttw_RS08200	COG3275	phosphorelay sensor kinase activity
bsdcttw_RS08205	COG4753	response regulator
bsdcttw_RS08205	COG2207	Transcriptional regulator
bsdcttw_RS08205	COG2207	Transcriptional regulator
bsdcttw_RS08205	COG4753	response regulator
bsdcttw_RS08210	COG4209	transmembrane transport
bsdcttw_RS08215	COG0395	ABC-type sugar transport system, permease component
bsdcttw_RS08230	COG3250	beta-galactosidase activity
bsdcttw_RS08235	COG1917	Cupin 2, conserved barrel domain protein
bsdcttw_RS08235	COG2207	Transcriptional regulator
bsdcttw_RS08240	COG2723	6-phospho-beta-galactosidase activity
bsdcttw_RS08245	COG1940	carbohydrate kinase activity
bsdcttw_RS08270	COG0583	DNA-binding transcription factor activity
bsdcttw_RS08280	COG2207	Transcriptional regulator
bsdcttw_RS08280	COG1917	Cupin 2, conserved barrel domain protein
bsdcttw_RS08290	COG0673	inositol 2-dehydrogenase activity
bsdcttw_RS08335	COG1733	regulation of RNA biosynthetic process
bsdcttw_RS08345	COG0346	lactoylglutathione lyase activity
bsdcttw_RS08355	COG2207	Transcriptional regulator
bsdcttw_RS08375	COG0003	Pfam Anion-transporting ATPase
bsdcttw_RS08385	COG0003	Pfam Anion-transporting ATPase
bsdcttw_RS08390	COG3158	transport of potassium into the cell
bsdcttw_RS08400	COG0789	Transcriptional regulator
bsdcttw_RS08410	COG1193	negative regulation of DNA recombination
bsdcttw_RS08415	COG1486	melibiose metabolic process
bsdcttw_RS08420	COG2971	BadF BadG BcrA BcrD
bsdcttw_RS08430	COG0577	efflux transmembrane transporter activity
bsdcttw_RS08430	COG1136	(ABC) transporter
bsdcttw_RS08440	COG5002	protein histidine kinase activity
bsdcttw_RS08445	COG0745	RESPONSE REGULATOR receiver
bsdcttw_RS08460	COG1131	(ABC) transporter
bsdcttw_RS08470	COG1175	transmembrane transport
bsdcttw_RS08475	COG0395	ABC-type sugar transport system, permease component
bsdcttw_RS08485	COG2972	Histidine kinase
bsdcttw_RS08490	COG0745	RESPONSE REGULATOR receiver
bsdcttw_RS08495	COG0363	glucosamine-6-phosphate deaminase activity
bsdcttw_RS08500	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
bsdcttw_RS08505	COG3525	Glycosyl hydrolase, family 20, catalytic domain
bsdcttw_RS08515	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
bsdcttw_RS08515	COG3711	transcriptional antiterminator
bsdcttw_RS08520	COG1447	Phosphotransferase system cellobiose-specific component IIA
bsdcttw_RS08530	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
bsdcttw_RS08535	COG2723	6-phospho-beta-galactosidase activity
bsdcttw_RS08545	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
bsdcttw_RS08565	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
bsdcttw_RS08570	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
bsdcttw_RS08590	COG0488	(ABC) transporter
bsdcttw_RS08610	COG0534	Mate efflux family protein
bsdcttw_RS08640	COG3459	Glycosyltransferase 36 associated
bsdcttw_RS08645	COG3459	Glycosyltransferase 36 associated
bsdcttw_RS08660	COG0306	phosphate transporter
bsdcttw_RS08675	COG0574	Belongs to the PEP-utilizing enzyme family
bsdcttw_RS08675	COG3848	Pyruvate phosphate dikinase
bsdcttw_RS08680	COG1131	(ABC) transporter
bsdcttw_RS08700	COG0583	DNA-binding transcription factor activity
bsdcttw_RS08705	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
bsdcttw_RS08720	COG0778	Nitroreductase
bsdcttw_RS08740	COG4209	transmembrane transport
bsdcttw_RS08745	COG0395	ABC-type sugar transport system, permease component
bsdcttw_RS08755	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
bsdcttw_RS08760	COG0572	uridine kinase
bsdcttw_RS08775	COG1472	Belongs to the glycosyl hydrolase 3 family
bsdcttw_RS08780	COG4166	transmembrane transport
bsdcttw_RS08785	COG0601	transmembrane transport
bsdcttw_RS08790	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
bsdcttw_RS08795	COG0444	Belongs to the ABC transporter superfamily
bsdcttw_RS08800	COG4608	Belongs to the ABC transporter superfamily
bsdcttw_RS08810	COG0583	DNA-binding transcription factor activity
bsdcttw_RS08825	COG2814	Major facilitator Superfamily
bsdcttw_RS08875	COG1486	melibiose metabolic process
bsdcttw_RS08880	COG4977	sequence-specific DNA binding
bsdcttw_RS08885	COG1733	regulation of RNA biosynthetic process
bsdcttw_RS08925	COG2271	Major facilitator Superfamily
bsdcttw_RS08930	COG0577	efflux transmembrane transporter activity
bsdcttw_RS08935	COG1136	(ABC) transporter
bsdcttw_RS08955	COG5002	protein histidine kinase activity
bsdcttw_RS08985	COG1307	EDD domain protein, DegV family
bsdcttw_RS08990	COG3708	Transcriptional regulator
bsdcttw_RS08990	COG2207	Transcriptional regulator
bsdcttw_RS09000	COG0823	Involved in the tonB-independent uptake of proteins
bsdcttw_RS09015	COG1959	2 iron, 2 sulfur cluster binding
bsdcttw_RS09045	COG1033	growth of symbiont in host cell
bsdcttw_RS09045	COG2409	Drug exporters of the RND superfamily
bsdcttw_RS09055	COG1695	Transcriptional regulator
bsdcttw_RS09060	COG0772	Belongs to the SEDS family
bsdcttw_RS09065	COG0824	Thioesterase
bsdcttw_RS09110	COG2855	membrane
bsdcttw_RS09115	COG0583	DNA-binding transcription factor activity
bsdcttw_RS09120	COG3706	GGDEF domain
bsdcttw_RS09130	COG3250	beta-galactosidase activity
bsdcttw_RS09135	COG2233	PERMEase
bsdcttw_RS09155	COG0477	Major facilitator Superfamily
bsdcttw_RS09160	COG1846	Transcriptional regulator
bsdcttw_RS09170	COG3022	response to hydroperoxide
bsdcttw_RS09190	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
bsdcttw_RS09210	COG1131	(ABC) transporter
bsdcttw_RS09230	COG2197	response regulator
bsdcttw_RS09250	COG1811	Na channel or pump
bsdcttw_RS09265	COG1368	sulfuric ester hydrolase activity
bsdcttw_RS09275	COG1151	hydroxylamine reductase activity
bsdcttw_RS09305	COG0488	(ABC) transporter
bsdcttw_RS09310	COG0583	DNA-binding transcription factor activity
bsdcttw_RS09320	COG2226	methyltransferase
bsdcttw_RS09340	COG4716	Myosin-crossreactive antigen
bsdcttw_RS09350	COG1950	PFAM Membrane protein of
bsdcttw_RS09395	COG2207	Transcriptional regulator
bsdcttw_RS09400	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
bsdcttw_RS09410	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
bsdcttw_RS09415	COG1609	Transcriptional regulator
bsdcttw_RS09420	COG1175	transmembrane transport
bsdcttw_RS09425	COG3833	ABC-type maltose transport systems, permease component
bsdcttw_RS09430	COG2182	Extracellular solute-binding protein
bsdcttw_RS09460	COG1725	Transcriptional regulator
bsdcttw_RS09465	COG1131	(ABC) transporter
bsdcttw_RS09475	COG0534	Mate efflux family protein
bsdcttw_RS09485	COG1687	branched-chain amino acid
bsdcttw_RS09490	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
bsdcttw_RS09510	COG3384	dioxygenase
bsdcttw_RS09520	COG2207	Transcriptional regulator
bsdcttw_RS09525	COG0740	serine-type endopeptidase activity
bsdcttw_RS09535	COG0583	DNA-binding transcription factor activity
bsdcttw_RS09540	COG0622	Phosphoesterase
bsdcttw_RS09545	COG0527	aspartate kinase activity
bsdcttw_RS09550	COG0697	spore germination
bsdcttw_RS09555	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
bsdcttw_RS09565	COG3620	sequence-specific DNA binding
bsdcttw_RS09570	COG1132	(ABC) transporter
bsdcttw_RS09585	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
bsdcttw_RS09590	COG1971	Probably functions as a manganese efflux pump
bsdcttw_RS09600	COG1321	iron dependent repressor
bsdcttw_RS09625	COG1472	Belongs to the glycosyl hydrolase 3 family
bsdcttw_RS09685	COG1309	transcriptional regulator
bsdcttw_RS09700	COG0667	Aldo Keto reductase
bsdcttw_RS09725	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
bsdcttw_RS09735	COG1122	ATPase activity
bsdcttw_RS09765	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
bsdcttw_RS09790	COG4977	sequence-specific DNA binding
bsdcttw_RS09790	COG1917	Cupin 2, conserved barrel domain protein
bsdcttw_RS09805	COG0534	Mate efflux family protein
bsdcttw_RS09820	COG1309	transcriptional regulator
bsdcttw_RS09830	COG0745	RESPONSE REGULATOR receiver
bsdcttw_RS09835	COG3850	Histidine kinase
bsdcttw_RS09835	COG5002	protein histidine kinase activity
bsdcttw_RS09845	COG1228	amidohydrolase
bsdcttw_RS09850	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
bsdcttw_RS09855	COG1082	Xylose isomerase domain protein TIM barrel
bsdcttw_RS09870	COG0531	amino acid
bsdcttw_RS09885	COG2188	Transcriptional regulator
bsdcttw_RS09935	COG1695	Transcriptional regulator
bsdcttw_RS09945	COG3708	Transcriptional regulator
bsdcttw_RS09945	COG2207	Transcriptional regulator
bsdcttw_RS09955	COG2188	Transcriptional regulator
bsdcttw_RS09965	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
bsdcttw_RS09975	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
bsdcttw_RS09985	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
bsdcttw_RS10015	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
bsdcttw_RS10020	COG0484	heat shock protein binding
bsdcttw_RS10035	COG4948	Mandelate Racemase Muconate Lactonizing
bsdcttw_RS10040	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
bsdcttw_RS10050	COG2972	Histidine kinase
bsdcttw_RS10055	COG4565	transcriptional regulatory protein
bsdcttw_RS10070	COG0395	ABC-type sugar transport system, permease component
bsdcttw_RS10105	COG2378	regulation of single-species biofilm formation
bsdcttw_RS10110	COG1309	transcriptional regulator
bsdcttw_RS10115	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
bsdcttw_RS10145	COG1136	(ABC) transporter
bsdcttw_RS10145	COG0577	efflux transmembrane transporter activity
bsdcttw_RS10155	COG0789	Transcriptional regulator
bsdcttw_RS10195	COG1686	Belongs to the peptidase S11 family
bsdcttw_RS10225	COG0275	rRNA processing
bsdcttw_RS10230	COG0366	Alpha amylase catalytic
bsdcttw_RS10250	COG0322	excinuclease ABC activity
bsdcttw_RS10255	COG0596	Alpha beta hydrolase
bsdcttw_RS10265	COG2188	Transcriptional regulator
bsdcttw_RS10270	COG1472	Belongs to the glycosyl hydrolase 3 family
bsdcttw_RS10295	COG3706	GGDEF domain
bsdcttw_RS10300	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
bsdcttw_RS10310	COG3191	aminopeptidase activity
bsdcttw_RS10315	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
bsdcttw_RS10340	COG1846	Transcriptional regulator
bsdcttw_RS10350	COG1132	(ABC) transporter
bsdcttw_RS10360	COG0456	acetyltransferase
bsdcttw_RS10370	COG2972	Histidine kinase
bsdcttw_RS10375	COG4753	response regulator
bsdcttw_RS10375	COG2207	Transcriptional regulator
bsdcttw_RS10390	COG0601	transmembrane transport
bsdcttw_RS10395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
bsdcttw_RS10400	COG0444	Belongs to the ABC transporter superfamily
bsdcttw_RS10405	COG4608	Belongs to the ABC transporter superfamily
bsdcttw_RS10420	COG1476	TRANSCRIPTIONal
bsdcttw_RS10430	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
bsdcttw_RS10440	COG0626	cystathionine gamma-synthase activity
bsdcttw_RS10445	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
bsdcttw_RS10470	COG1609	Transcriptional regulator
bsdcttw_RS10485	COG4209	transmembrane transport
bsdcttw_RS10490	COG0395	ABC-type sugar transport system, permease component
bsdcttw_RS10505	COG2226	methyltransferase
bsdcttw_RS10520	COG2199	diguanylate cyclase activity
bsdcttw_RS10530	COG1620	l-lactate permease
bsdcttw_RS10535	COG2086	electron transfer activity
bsdcttw_RS10540	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
bsdcttw_RS10545	COG0277	FAD linked oxidase domain protein
bsdcttw_RS10550	COG0840	transmembrane signaling receptor activity
bsdcttw_RS10560	COG1376	ErfK ybiS ycfS ynhG family protein
bsdcttw_RS10570	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
bsdcttw_RS10590	COG1309	transcriptional regulator
bsdcttw_RS10595	COG2814	Major facilitator Superfamily
bsdcttw_RS10605	COG5001	Diguanylate cyclase
bsdcttw_RS10605	COG3300	MHYT domain
bsdcttw_RS10610	COG5646	InterPro IPR014922
bsdcttw_RS10700	COG1695	Transcriptional regulator
bsdcttw_RS10705	COG4977	sequence-specific DNA binding
bsdcttw_RS10940	COG3548	integral membrane protein
bsdcttw_RS10945	COG2205	protein histidine kinase activity
bsdcttw_RS10950	COG0745	RESPONSE REGULATOR receiver
bsdcttw_RS10990	COG2203	Gaf domain
bsdcttw_RS10990	COG2199	diguanylate cyclase activity
bsdcttw_RS11020	COG0535	radical SAM domain protein
bsdcttw_RS11025	COG1131	(ABC) transporter
bsdcttw_RS11060	COG3507	Belongs to the glycosyl hydrolase 43 family
bsdcttw_RS11075	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
bsdcttw_RS11080	COG0583	DNA-binding transcription factor activity
bsdcttw_RS11100	COG2508	Transcriptional regulator
bsdcttw_RS11110	COG1028	Short-chain dehydrogenase reductase Sdr
bsdcttw_RS11120	COG1346	cytolysis
bsdcttw_RS11130	COG2186	Transcriptional regulator
bsdcttw_RS11145	COG1396	sequence-specific DNA binding
bsdcttw_RS11175	COG0395	ABC-type sugar transport system, permease component
bsdcttw_RS11180	COG1175	transmembrane transport
bsdcttw_RS11185	COG1653	transport
bsdcttw_RS11190	COG2972	Histidine kinase
bsdcttw_RS11195	COG2207	Transcriptional regulator
bsdcttw_RS11195	COG4753	response regulator
bsdcttw_RS11205	COG1070	Carbohydrate kinase
bsdcttw_RS11210	COG4806	L-rhamnose isomerase
bsdcttw_RS11215	COG0235	Class ii aldolase
bsdcttw_RS11225	COG0375	protein maturation
bsdcttw_RS11235	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
bsdcttw_RS11255	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
bsdcttw_RS11265	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
bsdcttw_RS11295	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
bsdcttw_RS11320	COG1797	cobyrinic acid a,c-diamide synthase activity
bsdcttw_RS11330	COG1122	ATPase activity
bsdcttw_RS11335	COG0310	cobalt ion transport
bsdcttw_RS11355	COG2188	Transcriptional regulator
bsdcttw_RS11360	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
bsdcttw_RS11365	COG2201	protein-glutamate methylesterase activity
bsdcttw_RS11370	COG2205	protein histidine kinase activity
bsdcttw_RS11375	COG2815	serine threonine protein kinase
bsdcttw_RS11375	COG0515	serine threonine protein kinase
bsdcttw_RS11385	COG1714	RDD family
bsdcttw_RS11390	COG2815	serine threonine protein kinase
bsdcttw_RS11390	COG0515	serine threonine protein kinase
bsdcttw_RS11405	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
bsdcttw_RS11410	COG0631	protein serine/threonine phosphatase activity
bsdcttw_RS11415	COG1716	ATPase activity
bsdcttw_RS11420	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
bsdcttw_RS11425	COG1846	Transcriptional regulator
bsdcttw_RS11440	COG1846	Transcriptional regulator
bsdcttw_RS11450	COG1131	(ABC) transporter
bsdcttw_RS11465	COG1733	regulation of RNA biosynthetic process
bsdcttw_RS11470	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
bsdcttw_RS11475	COG0785	Cytochrome C biogenesis protein
bsdcttw_RS11485	COG0519	Catalyzes the synthesis of GMP from XMP
bsdcttw_RS11510	COG0572	uridine kinase
bsdcttw_RS11535	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
bsdcttw_RS11550	COG3459	Glycosyltransferase 36 associated
bsdcttw_RS11555	COG4209	transmembrane transport
bsdcttw_RS11560	COG0395	ABC-type sugar transport system, permease component
bsdcttw_RS11580	COG1472	Belongs to the glycosyl hydrolase 3 family
bsdcttw_RS11595	COG1181	Belongs to the D-alanine--D-alanine ligase family
bsdcttw_RS11620	COG1012	belongs to the aldehyde dehydrogenase family
bsdcttw_RS11625	COG0484	heat shock protein binding
bsdcttw_RS11635	COG0025	NhaP-type Na H and K H
bsdcttw_RS11640	COG0667	Aldo Keto reductase
bsdcttw_RS11650	COG0840	transmembrane signaling receptor activity
bsdcttw_RS11660	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
bsdcttw_RS11660	COG0551	DNA topoisomerase type I activity
bsdcttw_RS11680	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
bsdcttw_RS11685	COG1725	Transcriptional regulator
bsdcttw_RS11705	COG1028	Short-chain dehydrogenase reductase Sdr
bsdcttw_RS11730	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
bsdcttw_RS11760	COG1136	(ABC) transporter
bsdcttw_RS11775	COG0346	lactoylglutathione lyase activity
bsdcttw_RS11785	COG1151	hydroxylamine reductase activity
bsdcttw_RS11805	COG0406	alpha-ribazole phosphatase activity
bsdcttw_RS11815	COG1136	(ABC) transporter
bsdcttw_RS11820	COG2205	protein histidine kinase activity
bsdcttw_RS11820	COG2198	Histidine kinase
bsdcttw_RS11820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
bsdcttw_RS11820	COG0784	Response regulator, receiver
bsdcttw_RS11825	COG0745	RESPONSE REGULATOR receiver
bsdcttw_RS11835	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
bsdcttw_RS11845	COG2205	protein histidine kinase activity
bsdcttw_RS11860	COG2814	Major facilitator Superfamily
bsdcttw_RS11865	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
bsdcttw_RS11870	COG0569	domain protein
bsdcttw_RS11885	COG0444	Belongs to the ABC transporter superfamily
bsdcttw_RS11890	COG4608	Belongs to the ABC transporter superfamily
bsdcttw_RS11895	COG0601	transmembrane transport
bsdcttw_RS11910	COG1472	Belongs to the glycosyl hydrolase 3 family
bsdcttw_RS11915	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
bsdcttw_RS11920	COG0840	transmembrane signaling receptor activity
bsdcttw_RS11940	COG0124	histidyl-tRNA synthetase
bsdcttw_RS11955	COG1131	(ABC) transporter
bsdcttw_RS11965	COG0577	efflux transmembrane transporter activity
bsdcttw_RS11965	COG0577	efflux transmembrane transporter activity
bsdcttw_RS11965	COG1136	(ABC) transporter
bsdcttw_RS11965	COG1136	(ABC) transporter
bsdcttw_RS11975	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
bsdcttw_RS11980	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
bsdcttw_RS12000	COG1653	transport
bsdcttw_RS12010	COG0395	ABC-type sugar transport system, permease component
bsdcttw_RS12030	COG0395	ABC-type sugar transport system, permease component
bsdcttw_RS12040	COG1609	Transcriptional regulator
bsdcttw_RS12050	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
bsdcttw_RS12065	COG0517	IMP dehydrogenase activity
bsdcttw_RS12075	COG1393	Belongs to the ArsC family
bsdcttw_RS12095	COG1606	tRNA processing
bsdcttw_RS12130	COG0300	oxidoreductase activity
bsdcttw_RS12145	COG2957	Belongs to the agmatine deiminase family
bsdcttw_RS12160	COG0386	Belongs to the glutathione peroxidase family
bsdcttw_RS12165	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
bsdcttw_RS12170	COG1879	ABC-type sugar transport system periplasmic component
bsdcttw_RS12180	COG0765	amino acid transport
bsdcttw_RS12185	COG1126	abc transporter atp-binding protein
bsdcttw_RS12195	COG3858	chitin binding
bsdcttw_RS12195	COG1388	LysM domain
bsdcttw_RS12205	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
bsdcttw_RS12210	COG1846	Transcriptional regulator
bsdcttw_RS12215	COG0386	Belongs to the glutathione peroxidase family
bsdcttw_RS12220	COG0840	transmembrane signaling receptor activity
bsdcttw_RS12225	COG1486	melibiose metabolic process
bsdcttw_RS12235	COG3250	beta-galactosidase activity
bsdcttw_RS12245	COG1918	ferrous iron import across plasma membrane
bsdcttw_RS12260	COG1404	Belongs to the peptidase S8 family
bsdcttw_RS12265	COG0586	Pfam SNARE associated Golgi protein
bsdcttw_RS12275	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
bsdcttw_RS12280	COG0363	glucosamine-6-phosphate deaminase activity
bsdcttw_RS12290	COG1253	flavin adenine dinucleotide binding
bsdcttw_RS12310	COG0396	ATPase activity
bsdcttw_RS12315	COG0719	Fe-S assembly protein
bsdcttw_RS12320	COG0719	Fe-S assembly protein
bsdcttw_RS12325	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
bsdcttw_RS12330	COG0822	iron-sulfur transferase activity
bsdcttw_RS12345	COG0456	acetyltransferase
bsdcttw_RS12350	COG0860	N-Acetylmuramoyl-L-alanine amidase
bsdcttw_RS12360	COG0404	The glycine cleavage system catalyzes the degradation of glycine
bsdcttw_RS12365	COG0509	glycine decarboxylation via glycine cleavage system
bsdcttw_RS12370	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
bsdcttw_RS12375	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
bsdcttw_RS12380	COG0095	Lipoate-protein ligase
bsdcttw_RS12385	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
bsdcttw_RS12395	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
bsdcttw_RS12400	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
bsdcttw_RS12405	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
bsdcttw_RS12410	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
bsdcttw_RS12415	COG0745	RESPONSE REGULATOR receiver
bsdcttw_RS12420	COG0673	inositol 2-dehydrogenase activity
bsdcttw_RS12425	COG0745	RESPONSE REGULATOR receiver
bsdcttw_RS12430	COG0642	Histidine kinase
bsdcttw_RS12435	COG1136	(ABC) transporter
bsdcttw_RS12445	COG1760	l-serine dehydratase
bsdcttw_RS12450	COG1760	l-serine dehydratase
bsdcttw_RS12475	COG1983	PspC domain protein
bsdcttw_RS12485	COG0840	transmembrane signaling receptor activity
bsdcttw_RS12500	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
bsdcttw_RS12500	COG1918	ferrous iron import across plasma membrane
bsdcttw_RS12505	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
bsdcttw_RS12505	COG1918	ferrous iron import across plasma membrane
bsdcttw_RS12525	COG1131	(ABC) transporter
bsdcttw_RS12540	COG1104	cysteine desulfurase activity
bsdcttw_RS12545	COG0037	tRNA processing
bsdcttw_RS12550	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
bsdcttw_RS12560	COG0287	Prephenate dehydrogenase
bsdcttw_RS12565	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
bsdcttw_RS12570	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
bsdcttw_RS12595	COG1940	carbohydrate kinase activity
bsdcttw_RS12600	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
bsdcttw_RS12610	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
bsdcttw_RS12615	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
bsdcttw_RS12620	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
bsdcttw_RS12625	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
bsdcttw_RS12630	COG2207	Transcriptional regulator
bsdcttw_RS12630	COG3708	Transcriptional regulator
bsdcttw_RS12635	COG2207	Transcriptional regulator
bsdcttw_RS12635	COG3708	Transcriptional regulator
bsdcttw_RS12675	COG0454	-acetyltransferase
bsdcttw_RS12685	COG2195	Cleaves the N-terminal amino acid of tripeptides
bsdcttw_RS12690	COG0129	dihydroxy-acid dehydratase activity
bsdcttw_RS12695	COG0028	Belongs to the TPP enzyme family
bsdcttw_RS12700	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
bsdcttw_RS12705	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
bsdcttw_RS12720	COG1482	cell wall glycoprotein biosynthetic process
bsdcttw_RS12730	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
bsdcttw_RS12735	COG0668	transmembrane transport
bsdcttw_RS12750	COG1501	Belongs to the glycosyl hydrolase 31 family
bsdcttw_RS12775	COG1307	EDD domain protein, DegV family
bsdcttw_RS12805	COG2972	Histidine kinase
bsdcttw_RS12810	COG3279	Response regulator of the LytR AlgR family
bsdcttw_RS12815	COG4213	ABC transporter substrate-binding protein
bsdcttw_RS12830	COG4214	carbohydrate transport
bsdcttw_RS12840	COG2315	Protein conserved in bacteria
bsdcttw_RS12850	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
bsdcttw_RS12850	COG0512	Glutamine amidotransferase of anthranilate synthase
bsdcttw_RS12855	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
bsdcttw_RS12860	COG0134	indole-3-glycerol-phosphate synthase activity
bsdcttw_RS12870	COG0133	tryptophan synthase activity
bsdcttw_RS12895	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
bsdcttw_RS12900	COG1132	(ABC) transporter
bsdcttw_RS12905	COG1132	(ABC) transporter
bsdcttw_RS12930	COG1959	2 iron, 2 sulfur cluster binding
bsdcttw_RS12940	COG0431	NADPH-dependent FMN reductase
bsdcttw_RS12990	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
bsdcttw_RS13015	COG1335	isochorismatase
bsdcttw_RS13020	COG1011	Hydrolase
bsdcttw_RS13035	COG0519	Catalyzes the synthesis of GMP from XMP
bsdcttw_RS13095	COG0640	Transcriptional regulator
bsdcttw_RS13100	COG2217	Heavy metal translocating P-type atpase
bsdcttw_RS13105	COG2217	Heavy metal translocating P-type atpase
bsdcttw_RS13150	COG2226	methyltransferase
bsdcttw_RS13190	COG1959	2 iron, 2 sulfur cluster binding
bsdcttw_RS13200	COG1028	Short-chain dehydrogenase reductase Sdr
bsdcttw_RS13205	COG1028	Short-chain dehydrogenase reductase Sdr
bsdcttw_RS13210	COG0789	Transcriptional regulator
bsdcttw_RS13270	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
bsdcttw_RS13285	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
bsdcttw_RS13315	COG5577	PFAM Coat F domain
bsdcttw_RS13325	COG1063	alcohol dehydrogenase
bsdcttw_RS13330	COG5577	PFAM Coat F domain
bsdcttw_RS13340	COG1028	Short-chain dehydrogenase reductase Sdr
bsdcttw_RS13345	COG3973	AAA domain
bsdcttw_RS13365	COG0346	lactoylglutathione lyase activity
bsdcttw_RS13370	COG0110	maltose O-acetyltransferase activity
bsdcttw_RS13380	COG0535	radical SAM domain protein
bsdcttw_RS13390	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
bsdcttw_RS13395	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
bsdcttw_RS13405	COG1649	PFAM Uncharacterised BCR, COG1649
bsdcttw_RS13410	COG2247	cell wall binding repeat
bsdcttw_RS13410	COG0860	N-Acetylmuramoyl-L-alanine amidase
bsdcttw_RS13415	COG4974	Belongs to the 'phage' integrase family
bsdcttw_RS13420	COG3848	Pyruvate phosphate dikinase
bsdcttw_RS13420	COG0574	Belongs to the PEP-utilizing enzyme family
bsdcttw_RS13445	COG1418	mRNA catabolic process
bsdcttw_RS13495	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
bsdcttw_RS13540	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
bsdcttw_RS13555	COG2244	polysaccharide biosynthetic process
bsdcttw_RS13580	COG1086	Polysaccharide biosynthesis protein
bsdcttw_RS13595	COG1215	transferase activity, transferring glycosyl groups
bsdcttw_RS13605	COG0438	transferase activity, transferring glycosyl groups
bsdcttw_RS13640	COG1388	LysM domain
bsdcttw_RS13645	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
bsdcttw_RS13660	COG0799	negative regulation of ribosome biogenesis
bsdcttw_RS13665	COG1713	HD superfamily hydrolase involved in NAD metabolism
bsdcttw_RS13670	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
bsdcttw_RS13675	COG1534	Rna-binding protein
bsdcttw_RS13680	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
bsdcttw_RS13685	COG0211	Belongs to the bacterial ribosomal protein bL27 family
bsdcttw_RS13695	COG0261	This protein binds to 23S rRNA in the presence of protein L20
bsdcttw_RS13710	COG1819	glycosyl
bsdcttw_RS13720	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
bsdcttw_RS13725	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
bsdcttw_RS13755	COG1172	Belongs to the binding-protein-dependent transport system permease family
bsdcttw_RS13760	COG1172	Belongs to the binding-protein-dependent transport system permease family
bsdcttw_RS13770	COG4213	ABC transporter substrate-binding protein
bsdcttw_RS13775	COG1879	ABC-type sugar transport system periplasmic component
bsdcttw_RS13780	COG2972	Histidine kinase
bsdcttw_RS13785	COG2207	Transcriptional regulator
bsdcttw_RS13785	COG4753	response regulator
bsdcttw_RS13790	COG0789	Transcriptional regulator
bsdcttw_RS13800	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
bsdcttw_RS13815	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
bsdcttw_RS13870	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
bsdcttw_RS13880	COG1686	Belongs to the peptidase S11 family
bsdcttw_RS13885	COG0252	asparaginase activity
bsdcttw_RS13920	COG0840	transmembrane signaling receptor activity
bsdcttw_RS13935	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
bsdcttw_RS13940	COG0659	secondary active sulfate transmembrane transporter activity
bsdcttw_RS13945	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
bsdcttw_RS13970	COG0564	pseudouridine synthase activity
bsdcttw_RS13980	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
bsdcttw_RS13985	COG3599	regulation of cell shape
bsdcttw_RS14000	COG1799	cell septum assembly
bsdcttw_RS14005	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
bsdcttw_RS14015	COG2155	Conserved Protein
bsdcttw_RS14025	COG1686	Belongs to the peptidase S11 family
bsdcttw_RS14030	COG1803	Methylglyoxal synthase
bsdcttw_RS14035	COG0772	Belongs to the SEDS family
bsdcttw_RS14040	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
bsdcttw_RS14045	COG2894	cell division
bsdcttw_RS14050	COG0850	regulation of cytokinetic process
bsdcttw_RS14055	COG0768	penicillin binding
bsdcttw_RS14075	COG2003	Belongs to the UPF0758 family
bsdcttw_RS14085	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
bsdcttw_RS14090	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
bsdcttw_RS14100	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
bsdcttw_RS14105	COG0328	RNA-DNA hybrid ribonuclease activity
bsdcttw_RS14170	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
bsdcttw_RS14185	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
bsdcttw_RS14190	COG3103	Sh3 type 3 domain protein
bsdcttw_RS14190	COG1388	LysM domain
bsdcttw_RS14190	COG0791	NLP P60 protein
bsdcttw_RS14195	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
bsdcttw_RS14200	COG0778	Nitroreductase
bsdcttw_RS14215	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
bsdcttw_RS14220	COG1160	GTP binding
bsdcttw_RS14230	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
bsdcttw_RS14235	COG1496	oxidoreductase activity
bsdcttw_RS14240	COG0792	nuclease activity
bsdcttw_RS14245	COG2257	FlhB HrpN YscU SpaS Family
bsdcttw_RS14250	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
bsdcttw_RS14255	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
bsdcttw_RS14265	COG0335	large ribosomal subunit rRNA binding
bsdcttw_RS14270	COG0336	Belongs to the RNA methyltransferase TrmD family
bsdcttw_RS14275	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
bsdcttw_RS14285	COG0228	four-way junction DNA binding
bsdcttw_RS14290	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
bsdcttw_RS14305	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
bsdcttw_RS14320	COG0511	ligase activity, forming carbon-carbon bonds
bsdcttw_RS14330	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
bsdcttw_RS14355	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
bsdcttw_RS14360	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
bsdcttw_RS14365	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
bsdcttw_RS14370	COG0552	protein localization to endoplasmic reticulum
bsdcttw_RS14380	COG0571	ribonuclease III activity
bsdcttw_RS14385	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
bsdcttw_RS14390	COG0416	fatty acid biosynthetic process
bsdcttw_RS14395	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
bsdcttw_RS14400	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
bsdcttw_RS14400	COG0539	negative regulation of cytoplasmic translation
bsdcttw_RS14410	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
bsdcttw_RS14415	COG2081	HI0933 family
bsdcttw_RS14425	COG1058	Belongs to the CinA family
bsdcttw_RS14425	COG1546	Belongs to the CinA family
bsdcttw_RS14430	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
bsdcttw_RS14435	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
bsdcttw_RS14445	COG0523	cobalamin synthesis protein
bsdcttw_RS14465	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
bsdcttw_RS14470	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
bsdcttw_RS14475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
bsdcttw_RS14480	COG1609	Transcriptional regulator
bsdcttw_RS14485	COG1904	glucuronate isomerase
bsdcttw_RS14490	COG1785	Belongs to the alkaline phosphatase family
bsdcttw_RS14525	COG0540	Belongs to the ATCase OTCase family
bsdcttw_RS14550	COG0395	ABC-type sugar transport system, permease component
bsdcttw_RS14575	COG0395	ABC-type sugar transport system, permease component
bsdcttw_RS14595	COG0514	ATP-dependent DNA helicase (RecQ)
bsdcttw_RS14620	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
bsdcttw_RS14625	COG2759	Belongs to the formate--tetrahydrofolate ligase family
bsdcttw_RS14635	COG0017	Asparaginyl-tRNA synthetase
bsdcttw_RS14645	COG0189	ligase activity
bsdcttw_RS14660	COG0740	serine-type endopeptidase activity
bsdcttw_RS14670	COG0612	Peptidase, M16
bsdcttw_RS14680	COG1185	polyribonucleotide nucleotidyltransferase activity
bsdcttw_RS14705	COG0697	spore germination
bsdcttw_RS14710	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
bsdcttw_RS14715	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
bsdcttw_RS14730	COG1686	Belongs to the peptidase S11 family
bsdcttw_RS14740	COG0577	efflux transmembrane transporter activity
bsdcttw_RS14740	COG1136	(ABC) transporter
bsdcttw_RS14745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
bsdcttw_RS14760	COG0681	Belongs to the peptidase S26 family
bsdcttw_RS14765	COG0681	Belongs to the peptidase S26 family
bsdcttw_RS14770	COG1758	RNA polymerase activity
bsdcttw_RS14775	COG2052	Domain of unknown function (DUF370)
bsdcttw_RS14780	COG1561	YicC-like family, N-terminal region
bsdcttw_RS14790	COG1293	RNA-binding protein homologous to eukaryotic snRNP
bsdcttw_RS14795	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
bsdcttw_RS14800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
bsdcttw_RS14805	COG0482	sulfurtransferase activity
bsdcttw_RS14810	COG0822	iron-sulfur transferase activity
bsdcttw_RS14820	COG1959	2 iron, 2 sulfur cluster binding
bsdcttw_RS14825	COG2244	polysaccharide biosynthetic process
bsdcttw_RS14830	COG5001	Diguanylate cyclase
bsdcttw_RS14845	COG4753	response regulator
bsdcttw_RS14845	COG2207	Transcriptional regulator
bsdcttw_RS14850	COG2972	Histidine kinase
bsdcttw_RS14860	COG1175	transmembrane transport
bsdcttw_RS14865	COG1653	transport
bsdcttw_RS14870	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
bsdcttw_RS14875	COG1979	alcohol dehydrogenase
bsdcttw_RS14895	COG1064	alcohol dehydrogenase
bsdcttw_RS14900	COG2135	peptidase activity
bsdcttw_RS14910	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
bsdcttw_RS14940	COG2267	carboxylic ester hydrolase activity
bsdcttw_RS14950	COG2207	Transcriptional regulator
bsdcttw_RS14955	COG1028	Short-chain dehydrogenase reductase Sdr
bsdcttw_RS14965	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
bsdcttw_RS14995	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
bsdcttw_RS15000	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
bsdcttw_RS15005	COG1187	pseudouridine synthase activity
bsdcttw_RS15020	COG1435	thymidine kinase activity
bsdcttw_RS15025	COG2323	membrane
bsdcttw_RS15030	COG1309	transcriptional regulator
bsdcttw_RS15035	COG2814	Major facilitator Superfamily
bsdcttw_RS15055	COG3250	beta-galactosidase activity
bsdcttw_RS15060	COG2207	Transcriptional regulator
bsdcttw_RS15060	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
bsdcttw_RS15065	COG0534	Mate efflux family protein
bsdcttw_RS15090	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
bsdcttw_RS15090	COG2207	Transcriptional regulator
bsdcttw_RS15105	COG0395	ABC-type sugar transport system, permease component
bsdcttw_RS15110	COG4209	transmembrane transport
bsdcttw_RS15115	COG1609	Transcriptional regulator
bsdcttw_RS15125	COG1137	ATPase activity
bsdcttw_RS15160	COG0493	'glutamate synthase
bsdcttw_RS15160	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
bsdcttw_RS15175	COG5002	protein histidine kinase activity
bsdcttw_RS15190	COG0488	(ABC) transporter
bsdcttw_RS15195	COG2246	polysaccharide biosynthetic process
bsdcttw_RS15235	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
bsdcttw_RS15245	COG1459	type II secretion system
bsdcttw_RS15255	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
bsdcttw_RS15260	COG1442	glycosyl transferase family 8
bsdcttw_RS15360	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
bsdcttw_RS15365	COG1982	Orn Lys Arg decarboxylase major
bsdcttw_RS15370	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
bsdcttw_RS15375	COG0577	efflux transmembrane transporter activity
bsdcttw_RS15375	COG1136	(ABC) transporter
bsdcttw_RS15380	COG1136	(ABC) transporter
bsdcttw_RS15380	COG0577	efflux transmembrane transporter activity
bsdcttw_RS15400	COG0826	peptidase U32
bsdcttw_RS15405	COG4122	O-methyltransferase activity
bsdcttw_RS15415	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
bsdcttw_RS15420	COG0735	belongs to the Fur family
bsdcttw_RS15430	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
bsdcttw_RS15435	COG4472	Bacterial protein of unknown function (DUF965)
bsdcttw_RS15440	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
bsdcttw_RS15450	COG0301	tRNA thio-modification
bsdcttw_RS15455	COG1104	cysteine desulfurase activity
bsdcttw_RS15460	COG1385	rRNA (uridine-N3-)-methyltransferase activity
bsdcttw_RS15465	COG2264	protein methyltransferase activity
bsdcttw_RS15470	COG0484	heat shock protein binding
bsdcttw_RS15475	COG0443	Heat shock 70 kDa protein
bsdcttw_RS15480	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
bsdcttw_RS15485	COG1420	regulation of RNA biosynthetic process
bsdcttw_RS15500	COG0641	radical SAM
bsdcttw_RS15525	COG0635	Involved in the biosynthesis of porphyrin-containing compound
bsdcttw_RS15530	COG2205	protein histidine kinase activity
bsdcttw_RS15545	COG0745	RESPONSE REGULATOR receiver
bsdcttw_RS15550	COG0481	GTPase activity
bsdcttw_RS15560	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
bsdcttw_RS15565	COG0268	Binds directly to 16S ribosomal RNA
bsdcttw_RS15570	COG0840	transmembrane signaling receptor activity
bsdcttw_RS15580	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
bsdcttw_RS15585	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
bsdcttw_RS15590	COG5492	domain, Protein
bsdcttw_RS15590	COG4932	domain protein
bsdcttw_RS15595	COG0484	heat shock protein binding
bsdcttw_RS15600	COG3458	cephalosporin-C deacetylase activity
bsdcttw_RS15625	COG3345	alpha-galactosidase
bsdcttw_RS15635	COG2207	Transcriptional regulator
bsdcttw_RS15635	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
bsdcttw_RS15640	COG3507	Belongs to the glycosyl hydrolase 43 family
bsdcttw_RS15650	COG2207	Transcriptional regulator
bsdcttw_RS15725	COG0477	Major facilitator Superfamily
bsdcttw_RS15740	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
bsdcttw_RS15740	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
bsdcttw_RS15745	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
bsdcttw_RS15750	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
bsdcttw_RS15765	COG0667	Aldo Keto reductase
bsdcttw_RS15770	COG0038	chloride channel
bsdcttw_RS15775	COG0789	Transcriptional regulator
bsdcttw_RS15780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
bsdcttw_RS15790	COG0196	riboflavin kinase activity
bsdcttw_RS15795	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
bsdcttw_RS15805	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
bsdcttw_RS15810	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
bsdcttw_RS15810	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
bsdcttw_RS15815	COG1358	cellular component organization or biogenesis
bsdcttw_RS15820	COG2740	Nucleic-acid-binding protein implicated in transcription termination
bsdcttw_RS15825	COG0195	Participates in both transcription termination and antitermination
bsdcttw_RS15830	COG0779	Required for maturation of 30S ribosomal subunits
bsdcttw_RS15840	COG0131	Imidazoleglycerol-phosphate dehydratase
bsdcttw_RS15845	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
bsdcttw_RS15850	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
bsdcttw_RS15855	COG0124	histidyl-tRNA synthetase
bsdcttw_RS15860	COG3331	DNA recombination
bsdcttw_RS15865	COG0564	pseudouridine synthase activity
bsdcttw_RS15870	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
bsdcttw_RS15875	COG1187	pseudouridine synthase activity
bsdcttw_RS15880	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
bsdcttw_RS15880	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
bsdcttw_RS15885	COG2357	RelA SpoT domain protein
bsdcttw_RS15890	COG0739	heme binding
bsdcttw_RS15900	COG1316	TRANSCRIPTIONal
bsdcttw_RS15905	COG2843	Capsule synthesis protein
bsdcttw_RS15910	COG2195	Cleaves the N-terminal amino acid of tripeptides
bsdcttw_RS15915	COG2848	UPF0210 protein
bsdcttw_RS15925	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
bsdcttw_RS15930	COG0849	cell division
bsdcttw_RS15935	COG0237	dephospho-CoA kinase activity
bsdcttw_RS15940	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
bsdcttw_RS15940	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
bsdcttw_RS15960	COG1027	Aspartate ammonia-lyase
bsdcttw_RS15965	COG1160	GTP binding
bsdcttw_RS15970	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
bsdcttw_RS15995	COG1191	sigma factor activity
bsdcttw_RS16005	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
bsdcttw_RS16010	COG1776	CheC inhibitor of MCP methylation
bsdcttw_RS16015	COG0835	chemotaxis
bsdcttw_RS16020	COG0643	Histidine kinase
bsdcttw_RS16020	COG2198	Histidine kinase
bsdcttw_RS16025	COG2201	protein-glutamate methylesterase activity
bsdcttw_RS16040	COG1419	protein localization to endoplasmic reticulum
bsdcttw_RS16045	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
bsdcttw_RS16050	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
bsdcttw_RS16055	COG4791	protein targeting
bsdcttw_RS16060	COG1987	bacterial-type flagellum assembly
bsdcttw_RS16065	COG1338	Plays a role in the flagellum-specific transport system
bsdcttw_RS16075	COG2201	protein-glutamate methylesterase activity
bsdcttw_RS16080	COG1776	CheC inhibitor of MCP methylation
bsdcttw_RS16080	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
bsdcttw_RS16085	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
bsdcttw_RS16095	COG1582	Flagellar protein (FlbD)
bsdcttw_RS16110	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
bsdcttw_RS16130	COG1157	protein secretion by the type III secretion system
bsdcttw_RS16140	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
bsdcttw_RS16150	COG1677	Flagellar hook-basal body complex protein FliE
bsdcttw_RS16155	COG1558	bacterial-type flagellum-dependent cell motility
bsdcttw_RS16160	COG1815	bacterial-type flagellum-dependent cell motility
bsdcttw_RS16170	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
bsdcttw_RS16175	COG0758	DNA mediated transformation
bsdcttw_RS16180	COG0606	chelatase, subunit chli
bsdcttw_RS16185	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
bsdcttw_RS16195	COG0658	competence protein
bsdcttw_RS16195	COG2333	competence protein COMEC
bsdcttw_RS16200	COG1191	sigma factor activity
bsdcttw_RS16205	COG1191	sigma factor activity
bsdcttw_RS16215	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
bsdcttw_RS16225	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
bsdcttw_RS16230	COG0772	Belongs to the SEDS family
bsdcttw_RS16235	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
bsdcttw_RS16250	COG0768	penicillin binding
bsdcttw_RS16260	COG0275	rRNA processing
bsdcttw_RS16265	COG2001	Belongs to the MraZ family
bsdcttw_RS16270	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
bsdcttw_RS16275	COG0012	GTP binding
bsdcttw_RS16285	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
bsdcttw_RS16295	COG0515	serine threonine protein kinase
bsdcttw_RS16295	COG2815	serine threonine protein kinase
bsdcttw_RS16300	COG0631	protein serine/threonine phosphatase activity
bsdcttw_RS16305	COG0820	rRNA (adenine-C2-)-methyltransferase activity
bsdcttw_RS16310	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
bsdcttw_RS16310	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
bsdcttw_RS16315	COG2738	Putative neutral zinc metallopeptidase
bsdcttw_RS16320	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
bsdcttw_RS16325	COG0242	peptide deformylase activity
bsdcttw_RS16330	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
bsdcttw_RS16335	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
bsdcttw_RS16365	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
bsdcttw_RS16375	COG4974	Belongs to the 'phage' integrase family
bsdcttw_RS16385	COG0494	nUDIX hydrolase
bsdcttw_RS16390	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
bsdcttw_RS16395	COG1418	mRNA catabolic process
bsdcttw_RS16400	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
bsdcttw_RS16410	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
bsdcttw_RS16415	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
bsdcttw_RS16425	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
bsdcttw_RS16430	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
bsdcttw_RS16435	COG2081	HI0933 family
bsdcttw_RS16445	COG2201	protein-glutamate methylesterase activity
bsdcttw_RS16450	COG0495	leucyl-tRNA aminoacylation
bsdcttw_RS16455	COG0463	Glycosyl transferase, family 2
bsdcttw_RS16465	COG2244	polysaccharide biosynthetic process
bsdcttw_RS16475	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
bsdcttw_RS16485	COG1702	phosphate starvation-inducible protein PhoH
bsdcttw_RS16500	COG0828	Belongs to the bacterial ribosomal protein bS21 family
bsdcttw_RS16505	COG0840	transmembrane signaling receptor activity
bsdcttw_RS16505	COG5278	phosphoserine phosphatase activity
bsdcttw_RS16510	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
bsdcttw_RS16545	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
bsdcttw_RS16555	COG0750	zinc metalloprotease
bsdcttw_RS16560	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
bsdcttw_RS16565	COG4589	Belongs to the CDS family
bsdcttw_RS16575	COG0233	cytoplasmic translational termination
bsdcttw_RS16600	COG0628	permease
bsdcttw_RS16605	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
bsdcttw_RS16610	COG0052	Belongs to the universal ribosomal protein uS2 family
bsdcttw_RS16620	COG1051	belongs to the nudix hydrolase family
bsdcttw_RS16625	COG0768	penicillin binding
bsdcttw_RS16630	COG0772	Belongs to the SEDS family
bsdcttw_RS16635	COG0826	peptidase U32
bsdcttw_RS16645	COG2255	four-way junction helicase activity
bsdcttw_RS16650	COG0632	four-way junction helicase activity
bsdcttw_RS16660	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
bsdcttw_RS16680	COG0333	Belongs to the bacterial ribosomal protein bL32 family
bsdcttw_RS16690	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
bsdcttw_RS16695	COG0280	phosphate acetyltransferase
bsdcttw_RS16715	COG3279	Response regulator of the LytR AlgR family
bsdcttw_RS16720	COG1323	Belongs to the UPF0348 family
bsdcttw_RS16725	COG1164	Oligoendopeptidase f
bsdcttw_RS16740	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
bsdcttw_RS16745	COG0742	ribosomal rna small subunit methyltransferase
bsdcttw_RS16760	COG0463	Glycosyl transferase, family 2
bsdcttw_RS16765	COG0562	UDP-galactopyranose mutase
bsdcttw_RS16770	COG0464	growth
bsdcttw_RS16775	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
bsdcttw_RS16780	COG1461	Dihydroxyacetone kinase
bsdcttw_RS16785	COG1302	Protein conserved in bacteria
bsdcttw_RS16795	COG0227	Belongs to the bacterial ribosomal protein bL28 family
bsdcttw_RS16805	COG1472	Belongs to the glycosyl hydrolase 3 family
bsdcttw_RS16810	COG0383	alpha-mannosidase activity
bsdcttw_RS16820	COG0395	ABC-type sugar transport system, permease component
bsdcttw_RS16825	COG4209	transmembrane transport
bsdcttw_RS16830	COG1609	Transcriptional regulator
bsdcttw_RS16835	COG1472	Belongs to the glycosyl hydrolase 3 family
bsdcttw_RS16880	COG0860	N-Acetylmuramoyl-L-alanine amidase
bsdcttw_RS16880	COG1388	LysM domain
bsdcttw_RS16890	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
bsdcttw_RS16905	COG1131	(ABC) transporter
bsdcttw_RS16925	COG0107	imidazoleglycerol-phosphate synthase activity
bsdcttw_RS16930	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
bsdcttw_RS16940	COG0835	chemotaxis
bsdcttw_RS16940	COG0784	Response regulator, receiver
bsdcttw_RS16985	COG2337	Toxic component of a toxin-antitoxin (TA) module
bsdcttw_RS16990	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
bsdcttw_RS16995	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
bsdcttw_RS16995	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
bsdcttw_RS17000	COG0736	holo-[acyl-carrier-protein] synthase activity
bsdcttw_RS17010	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
bsdcttw_RS17015	COG0488	(ABC) transporter
bsdcttw_RS17025	COG4213	ABC transporter substrate-binding protein
bsdcttw_RS17030	COG2207	Transcriptional regulator
bsdcttw_RS17035	COG2972	Histidine kinase
bsdcttw_RS17050	COG1172	Belongs to the binding-protein-dependent transport system permease family
bsdcttw_RS17060	COG4213	ABC transporter substrate-binding protein
bsdcttw_RS17065	COG1802	Transcriptional regulator
bsdcttw_RS17070	COG0473	3-isopropylmalate dehydrogenase activity
bsdcttw_RS17075	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
bsdcttw_RS17080	COG0549	Belongs to the carbamate kinase family
bsdcttw_RS17085	COG0840	transmembrane signaling receptor activity
bsdcttw_RS17090	COG0367	asparagine synthase
bsdcttw_RS17095	COG0840	transmembrane signaling receptor activity
bsdcttw_RS17095	COG3290	protein histidine kinase activity
bsdcttw_RS17100	COG1464	Belongs to the NlpA lipoprotein family
bsdcttw_RS17105	COG2011	ABC-type metal ion transport system permease component
bsdcttw_RS17110	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
bsdcttw_RS17125	COG5001	Diguanylate cyclase
bsdcttw_RS17125	COG3300	MHYT domain
bsdcttw_RS17130	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
bsdcttw_RS17140	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
bsdcttw_RS17145	COG1802	Transcriptional regulator
bsdcttw_RS17150	COG0246	Mannitol dehydrogenase
bsdcttw_RS17155	COG1312	Catalyzes the dehydration of D-mannonate
bsdcttw_RS17170	COG0840	transmembrane signaling receptor activity
bsdcttw_RS17185	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
bsdcttw_RS17190	COG1404	Belongs to the peptidase S8 family
bsdcttw_RS17195	COG1592	Rubrerythrin
bsdcttw_RS17200	COG1013	pyruvate-flavodoxin oxidoreductase activity
bsdcttw_RS17205	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
bsdcttw_RS17205	COG0674	pyruvate-flavodoxin oxidoreductase activity
bsdcttw_RS17225	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
bsdcttw_RS17230	COG1268	BioY protein
bsdcttw_RS17235	COG1396	sequence-specific DNA binding
bsdcttw_RS17240	COG3842	ATPase activity
bsdcttw_RS17245	COG1176	ABC-type spermidine putrescine transport system, permease component I
bsdcttw_RS17250	COG1177	transmembrane transport
bsdcttw_RS17260	COG1846	Transcriptional regulator
bsdcttw_RS17260	COG0456	acetyltransferase
bsdcttw_RS17265	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
bsdcttw_RS17280	COG1854	S-ribosylhomocysteine lyase activity
bsdcttw_RS17295	COG1376	ErfK ybiS ycfS ynhG family protein
bsdcttw_RS17300	COG1132	(ABC) transporter
bsdcttw_RS17320	COG4608	Belongs to the ABC transporter superfamily
bsdcttw_RS17325	COG0444	Belongs to the ABC transporter superfamily
bsdcttw_RS17330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
bsdcttw_RS17335	COG0601	transmembrane transport
bsdcttw_RS17345	COG0148	phosphopyruvate hydratase activity
bsdcttw_RS17350	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
bsdcttw_RS17355	COG0165	Argininosuccinate lyase
bsdcttw_RS17360	COG1136	(ABC) transporter
bsdcttw_RS17380	COG0640	Transcriptional regulator
bsdcttw_RS17390	COG1131	(ABC) transporter
bsdcttw_RS17400	COG1937	Protein conserved in bacteria
bsdcttw_RS17420	COG4555	ABC transporter
bsdcttw_RS17425	COG0840	transmembrane signaling receptor activity
bsdcttw_RS17440	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
bsdcttw_RS17445	COG1609	Transcriptional regulator
bsdcttw_RS17450	COG1554	hydrolase, family 65, central catalytic
bsdcttw_RS17460	COG0395	ABC-type sugar transport system, permease component
bsdcttw_RS17465	COG1175	transmembrane transport
bsdcttw_RS17475	COG1968	undecaprenyl-diphosphatase activity
bsdcttw_RS17510	COG2333	competence protein COMEC
bsdcttw_RS17510	COG0658	competence protein
bsdcttw_RS17520	COG5002	protein histidine kinase activity
bsdcttw_RS17540	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
bsdcttw_RS17545	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
bsdcttw_RS17550	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
bsdcttw_RS17555	COG0424	maF-like protein
bsdcttw_RS17560	COG0137	argininosuccinate synthase activity
bsdcttw_RS17575	COG0561	phosphatase activity
bsdcttw_RS17605	COG1609	Transcriptional regulator
bsdcttw_RS17615	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
bsdcttw_RS17625	COG1126	abc transporter atp-binding protein
bsdcttw_RS17630	COG0765	amino acid transport
bsdcttw_RS17635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
bsdcttw_RS17640	COG0588	phosphoglycerate mutase activity
bsdcttw_RS17655	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
bsdcttw_RS17685	COG5002	protein histidine kinase activity
bsdcttw_RS17690	COG0745	RESPONSE REGULATOR receiver
bsdcttw_RS17715	COG1584	GPR1 FUN34 yaaH family protein
bsdcttw_RS17760	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
bsdcttw_RS17765	COG0557	exoribonuclease II activity
bsdcttw_RS17775	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
bsdcttw_RS17780	COG0149	triose-phosphate isomerase activity
bsdcttw_RS17805	COG0297	glycogen (starch) synthase activity
bsdcttw_RS17810	COG0745	RESPONSE REGULATOR receiver
bsdcttw_RS17815	COG0750	zinc metalloprotease
bsdcttw_RS17820	COG0497	DNA recombination
bsdcttw_RS17850	COG0217	transcriptional regulatory protein
bsdcttw_RS17855	COG1438	arginine binding
bsdcttw_RS17860	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
bsdcttw_RS17865	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
bsdcttw_RS17870	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
bsdcttw_RS17880	COG1722	exodeoxyribonuclease VII activity
bsdcttw_RS17885	COG1570	exodeoxyribonuclease VII activity
bsdcttw_RS17890	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
bsdcttw_RS17905	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
bsdcttw_RS17910	COG1882	Formate acetyltransferase
bsdcttw_RS17950	COG3854	ATPases associated with a variety of cellular activities
bsdcttw_RS17960	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
bsdcttw_RS17970	COG0066	3-isopropylmalate dehydratase activity
bsdcttw_RS17975	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
bsdcttw_RS17980	COG0473	3-isopropylmalate dehydrogenase activity
bsdcttw_RS17985	COG0583	DNA-binding transcription factor activity
bsdcttw_RS17995	COG1194	a g-specific adenine glycosylase
bsdcttw_RS18000	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
bsdcttw_RS18020	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
bsdcttw_RS18025	COG0077	Prephenate dehydratase
bsdcttw_RS18025	COG1605	Chorismate mutase
bsdcttw_RS18035	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
bsdcttw_RS18040	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
bsdcttw_RS18055	COG0632	four-way junction helicase activity
bsdcttw_RS18070	COG1131	(ABC) transporter
bsdcttw_RS18075	COG4585	Histidine kinase
bsdcttw_RS18080	COG2197	response regulator
bsdcttw_RS18090	COG4608	Belongs to the ABC transporter superfamily
bsdcttw_RS18095	COG0444	Belongs to the ABC transporter superfamily
bsdcttw_RS18105	COG0601	transmembrane transport
bsdcttw_RS18130	COG1388	LysM domain
bsdcttw_RS18130	COG3858	chitin binding
bsdcttw_RS18135	COG1307	EDD domain protein, DegV family
bsdcttw_RS18140	COG1116	anion transmembrane transporter activity
bsdcttw_RS18160	COG1116	anion transmembrane transporter activity
bsdcttw_RS18165	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
bsdcttw_RS18180	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
bsdcttw_RS18180	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
bsdcttw_RS18185	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
bsdcttw_RS18240	COG1523	belongs to the glycosyl hydrolase 13 family
bsdcttw_RS18265	COG1131	(ABC) transporter
bsdcttw_RS18280	COG0488	(ABC) transporter
bsdcttw_RS18285	COG1012	belongs to the aldehyde dehydrogenase family
bsdcttw_RS18300	COG1177	transmembrane transport
bsdcttw_RS18305	COG1176	ABC-type spermidine putrescine transport system, permease component I
bsdcttw_RS18315	COG0347	Belongs to the P(II) protein family
bsdcttw_RS18320	COG1396	sequence-specific DNA binding
bsdcttw_RS18330	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
bsdcttw_RS18340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
bsdcttw_RS18345	COG0765	amino acid transport
bsdcttw_RS18350	COG1126	abc transporter atp-binding protein
bsdcttw_RS18370	COG4989	oxidoreductase activity
bsdcttw_RS18375	COG1253	flavin adenine dinucleotide binding
bsdcttw_RS18435	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
bsdcttw_RS18440	COG0167	dihydroorotate dehydrogenase activity
bsdcttw_RS18445	COG0543	2 iron, 2 sulfur cluster binding
bsdcttw_RS18460	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
bsdcttw_RS18465	COG0006	proline dipeptidase activity
bsdcttw_RS18485	COG0626	cystathionine gamma-synthase activity
bsdcttw_RS18490	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
bsdcttw_RS18500	COG1136	(ABC) transporter
bsdcttw_RS18500	COG0577	efflux transmembrane transporter activity
bsdcttw_RS18505	COG5002	protein histidine kinase activity
bsdcttw_RS18515	COG0284	orotidine-5'-phosphate decarboxylase activity
bsdcttw_RS18520	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
bsdcttw_RS18525	COG0494	nUDIX hydrolase
bsdcttw_RS18545	COG0673	inositol 2-dehydrogenase activity
bsdcttw_RS18550	COG0673	inositol 2-dehydrogenase activity
bsdcttw_RS18565	COG0463	Glycosyl transferase, family 2
bsdcttw_RS18565	COG0457	Tetratricopeptide repeat
bsdcttw_RS18605	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
bsdcttw_RS18670	COG2207	Transcriptional regulator
bsdcttw_RS18670	COG3708	Transcriptional regulator
bsdcttw_RS18720	COG0582	viral genome integration into host DNA
bsdcttw_RS18735	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
bsdcttw_RS18740	COG0662	Cupin 2, conserved barrel domain protein
bsdcttw_RS18740	COG2207	Transcriptional regulator
bsdcttw_RS18745	COG0840	transmembrane signaling receptor activity
bsdcttw_RS18760	COG3708	Transcriptional regulator
bsdcttw_RS18760	COG2207	Transcriptional regulator
bsdcttw_RS18770	COG2207	Transcriptional regulator
bsdcttw_RS18770	COG3708	Transcriptional regulator
bsdcttw_RS18805	COG0656	L-ascorbic acid biosynthetic process
bsdcttw_RS18810	COG1205	dead DEAH box helicase
bsdcttw_RS18810	COG1111	helicase
bsdcttw_RS18850	COG0596	Alpha beta hydrolase
bsdcttw_RS18885	COG2801	Transposase and inactivated derivatives
bsdcttw_RS18895	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
bsdcttw_RS18910	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
bsdcttw_RS18915	COG0187	DNA topoisomerase II activity
bsdcttw_RS18985	COG2207	Transcriptional regulator
bsdcttw_RS18990	COG1132	(ABC) transporter
bsdcttw_RS18995	COG1132	(ABC) transporter
bsdcttw_RS19010	COG1162	GTPase activity
bsdcttw_RS19020	COG3706	GGDEF domain
bsdcttw_RS19025	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
bsdcttw_RS19030	COG2270	Major facilitator Superfamily
bsdcttw_RS19085	COG1132	(ABC) transporter
bsdcttw_RS19090	COG1132	(ABC) transporter
bsdcttw_RS19100	COG3620	sequence-specific DNA binding
bsdcttw_RS19105	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
bsdcttw_RS19115	COG2755	lipolytic protein G-D-S-L family
bsdcttw_RS19115	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
bsdcttw_RS19120	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
bsdcttw_RS19125	COG1162	GTPase activity
bsdcttw_RS19160	COG0745	RESPONSE REGULATOR receiver
bsdcttw_RS19160	COG2972	Histidine kinase
bsdcttw_RS19165	COG0493	'glutamate synthase
bsdcttw_RS19180	COG2207	Transcriptional regulator
bsdcttw_RS19190	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
bsdcttw_RS19205	COG1132	(ABC) transporter
bsdcttw_RS19210	COG1132	(ABC) transporter
bsdcttw_RS19220	COG0484	heat shock protein binding
bsdcttw_RS19240	COG3973	AAA domain
bsdcttw_RS19275	COG1132	(ABC) transporter
bsdcttw_RS19280	COG1653	transport
bsdcttw_RS19285	COG0395	ABC-type sugar transport system, permease component
bsdcttw_RS19290	COG4209	transmembrane transport
bsdcttw_RS19320	COG3328	transposase activity
bsdcttw_RS19335	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
bsdcttw_RS19350	COG1216	Glycosyl transferase, family 2
bsdcttw_RS19350	COG1442	glycosyl transferase family 8
bsdcttw_RS19360	COG0438	transferase activity, transferring glycosyl groups
bsdcttw_RS19365	COG1216	Glycosyl transferase, family 2
bsdcttw_RS19365	COG0463	Glycosyl transferase, family 2
bsdcttw_RS19380	COG0438	transferase activity, transferring glycosyl groups
bsdcttw_RS19390	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
bsdcttw_RS19425	COG1216	Glycosyl transferase, family 2
bsdcttw_RS19435	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
bsdcttw_RS19440	COG3773	Cell wall hydrolase
bsdcttw_RS19455	COG1131	(ABC) transporter
bsdcttw_RS19490	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
bsdcttw_RS19495	COG0358	DNA primase activity
bsdcttw_RS19500	COG0232	Belongs to the dGTPase family. Type 2 subfamily
bsdcttw_RS19515	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
bsdcttw_RS19520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
bsdcttw_RS19555	COG3778	Protein conserved in bacteria
bsdcttw_RS19560	COG3299	homolog of phage Mu protein gp47
bsdcttw_RS19645	COG5566	PFAM Mor transcription activator
bsdcttw_RS19650	COG2217	Heavy metal translocating P-type atpase
bsdcttw_RS19655	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
bsdcttw_RS19665	COG0215	cysteine-tRNA ligase activity
bsdcttw_RS19670	COG1045	serine acetyltransferase
bsdcttw_RS19680	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
bsdcttw_RS19695	COG0840	transmembrane signaling receptor activity
bsdcttw_RS19700	COG0295	cytidine deaminase activity
bsdcttw_RS19705	COG2723	6-phospho-beta-galactosidase activity
bsdcttw_RS19710	COG0395	ABC-type sugar transport system, permease component
bsdcttw_RS19715	COG4209	transmembrane transport
bsdcttw_RS19725	COG2207	Transcriptional regulator
bsdcttw_RS19735	COG1959	2 iron, 2 sulfur cluster binding
bsdcttw_RS19740	COG2873	o-acetylhomoserine
bsdcttw_RS19760	COG0488	(ABC) transporter
bsdcttw_RS19765	COG3773	Cell wall hydrolase
bsdcttw_RS19765	COG3409	Peptidoglycan-binding domain 1 protein
bsdcttw_RS19775	COG1091	dTDP-4-dehydrorhamnose reductase activity
bsdcttw_RS19795	COG1028	Short-chain dehydrogenase reductase Sdr
bsdcttw_RS19800	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
bsdcttw_RS19810	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
bsdcttw_RS19830	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
bsdcttw_RS19835	COG1263	PTS System
bsdcttw_RS19835	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
bsdcttw_RS19840	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
bsdcttw_RS19840	COG1263	PTS System
bsdcttw_RS19840	COG2190	(PTS) system
bsdcttw_RS19845	COG3711	transcriptional antiterminator
bsdcttw_RS19855	COG0534	Mate efflux family protein
bsdcttw_RS19865	COG1695	Transcriptional regulator
bsdcttw_RS19870	COG2195	Cleaves the N-terminal amino acid of tripeptides
bsdcttw_RS19875	COG1027	Aspartate ammonia-lyase
bsdcttw_RS19880	COG1522	sequence-specific DNA binding
bsdcttw_RS19885	COG2199	diguanylate cyclase activity
bsdcttw_RS19885	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
bsdcttw_RS19890	COG3870	Protein conserved in bacteria
bsdcttw_RS19900	COG1668	transmembrane transport
bsdcttw_RS19905	COG4152	abc transporter atp-binding protein
bsdcttw_RS19910	COG0531	amino acid
bsdcttw_RS19930	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
bsdcttw_RS19940	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
bsdcttw_RS19945	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
bsdcttw_RS19955	COG1136	(ABC) transporter
bsdcttw_RS19960	COG4591	ABC-type transport system involved in lipoprotein release permease component
bsdcttw_RS19985	COG0395	ABC-type sugar transport system, permease component
bsdcttw_RS19990	COG4209	transmembrane transport
bsdcttw_RS20015	COG1126	abc transporter atp-binding protein
bsdcttw_RS20020	COG0765	amino acid transport
bsdcttw_RS20030	COG0318	PFAM AMP-dependent synthetase and ligase
bsdcttw_RS20035	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
bsdcttw_RS20045	COG1051	belongs to the nudix hydrolase family
bsdcttw_RS20050	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
bsdcttw_RS20070	COG1175	transmembrane transport
bsdcttw_RS20075	COG0395	ABC-type sugar transport system, permease component
bsdcttw_RS20090	COG0456	acetyltransferase
bsdcttw_RS20090	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
bsdcttw_RS20095	COG1201	RNA secondary structure unwinding
bsdcttw_RS20100	COG0840	transmembrane signaling receptor activity
bsdcttw_RS20105	COG0778	Nitroreductase
bsdcttw_RS20110	COG0395	ABC-type sugar transport system, permease component
bsdcttw_RS20115	COG4209	transmembrane transport
bsdcttw_RS20135	COG3250	beta-galactosidase activity
bsdcttw_RS20145	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
bsdcttw_RS20150	COG0596	Alpha beta hydrolase
bsdcttw_RS20150	COG0508	dehydrogenase complex catalyzes the overall conversion of
bsdcttw_RS20160	COG1846	Transcriptional regulator
bsdcttw_RS20170	COG2207	Transcriptional regulator
bsdcttw_RS20170	COG1609	Transcriptional regulator
bsdcttw_RS20190	COG1609	Transcriptional regulator
bsdcttw_RS20210	COG0395	ABC-type sugar transport system, permease component
bsdcttw_RS20215	COG4209	transmembrane transport
bsdcttw_RS20220	COG0667	Aldo Keto reductase
bsdcttw_RS20240	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
bsdcttw_RS20245	COG0191	fructose-bisphosphate aldolase activity
bsdcttw_RS20265	COG1349	DNA-binding transcription factor activity
bsdcttw_RS20280	COG0583	DNA-binding transcription factor activity
bsdcttw_RS20295	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
bsdcttw_RS20300	COG0383	alpha-mannosidase activity
bsdcttw_RS20315	COG0395	ABC-type sugar transport system, permease component
bsdcttw_RS20320	COG4209	transmembrane transport
bsdcttw_RS20325	COG2207	Transcriptional regulator
bsdcttw_RS20325	COG4753	response regulator
bsdcttw_RS20330	COG2972	Histidine kinase
bsdcttw_RS20335	COG1609	Transcriptional regulator
bsdcttw_RS20350	COG0737	Belongs to the 5'-nucleotidase family
bsdcttw_RS20355	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
bsdcttw_RS20360	COG0113	porphobilinogen synthase activity
bsdcttw_RS20370	COG0181	hydroxymethylbilane synthase activity
bsdcttw_RS20375	COG1648	precorrin-2 dehydrogenase activity
bsdcttw_RS20375	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
bsdcttw_RS20380	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
bsdcttw_RS20385	COG3708	Transcriptional regulator
bsdcttw_RS20385	COG2207	Transcriptional regulator
bsdcttw_RS20395	COG0534	Mate efflux family protein
bsdcttw_RS20405	COG0789	Transcriptional regulator
bsdcttw_RS20430	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
bsdcttw_RS20440	COG2207	Transcriptional regulator
bsdcttw_RS20440	COG3708	Transcriptional regulator
bsdcttw_RS20475	COG5002	protein histidine kinase activity
bsdcttw_RS20525	COG1131	(ABC) transporter
bsdcttw_RS20530	COG1309	transcriptional regulator
bsdcttw_RS20545	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
bsdcttw_RS20550	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
bsdcttw_RS20575	COG1501	Belongs to the glycosyl hydrolase 31 family
bsdcttw_RS20580	COG2207	Transcriptional regulator
bsdcttw_RS20580	COG1917	Cupin 2, conserved barrel domain protein
bsdcttw_RS20590	COG2207	Transcriptional regulator
bsdcttw_RS20590	COG4753	response regulator
bsdcttw_RS20595	COG2972	Histidine kinase
bsdcttw_RS20620	COG1619	proteins homologs of microcin C7 resistance protein MccF
bsdcttw_RS20635	COG1309	transcriptional regulator
bsdcttw_RS20640	COG1028	Short-chain dehydrogenase reductase Sdr
bsdcttw_RS20655	COG0789	Transcriptional regulator
bsdcttw_RS20660	COG0673	inositol 2-dehydrogenase activity
bsdcttw_RS20665	COG0673	inositol 2-dehydrogenase activity
bsdcttw_RS20670	COG1882	Formate acetyltransferase
bsdcttw_RS20680	COG1917	Cupin 2, conserved barrel domain protein
bsdcttw_RS20680	COG2169	Transcriptional regulator
bsdcttw_RS20705	COG2207	Transcriptional regulator
bsdcttw_RS20705	COG3708	Transcriptional regulator
bsdcttw_RS20720	COG0574	Belongs to the PEP-utilizing enzyme family
bsdcttw_RS20720	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
bsdcttw_RS20725	COG0423	glycine-tRNA ligase activity
bsdcttw_RS20735	COG1381	Involved in DNA repair and RecF pathway recombination
bsdcttw_RS20745	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
bsdcttw_RS20765	COG1597	lipid kinase activity
bsdcttw_RS20785	COG3906	Belongs to the UPF0473 family
bsdcttw_RS20790	COG0210	DNA helicase
bsdcttw_RS20795	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
bsdcttw_RS20800	COG0667	Aldo Keto reductase
bsdcttw_RS20810	COG0714	Associated with various cellular activities
bsdcttw_RS20845	COG0577	efflux transmembrane transporter activity
bsdcttw_RS20860	COG1136	(ABC) transporter
bsdcttw_RS20865	COG0628	permease
bsdcttw_RS20880	COG0714	Associated with various cellular activities
bsdcttw_RS20885	COG1392	Phosphate transport regulator
bsdcttw_RS20890	COG0306	phosphate transporter
bsdcttw_RS20895	COG2205	protein histidine kinase activity
bsdcttw_RS20900	COG0745	RESPONSE REGULATOR receiver
bsdcttw_RS20955	COG3708	Transcriptional regulator
bsdcttw_RS20955	COG2207	Transcriptional regulator
bsdcttw_RS20975	COG5566	PFAM Mor transcription activator
bsdcttw_RS20985	COG1175	transmembrane transport
bsdcttw_RS20995	COG1609	Transcriptional regulator
bsdcttw_RS21015	COG2814	Major facilitator Superfamily
bsdcttw_RS21025	COG0583	DNA-binding transcription factor activity
bsdcttw_RS21035	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
bsdcttw_RS21040	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
bsdcttw_RS21055	COG1078	dGTPase activity
bsdcttw_RS21080	COG2205	protein histidine kinase activity
bsdcttw_RS21120	COG0395	ABC-type sugar transport system, permease component
bsdcttw_RS21125	COG4209	transmembrane transport
bsdcttw_RS21130	COG2972	Histidine kinase
bsdcttw_RS21135	COG3279	Response regulator of the LytR AlgR family
bsdcttw_RS21140	COG1309	transcriptional regulator
bsdcttw_RS21150	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
bsdcttw_RS21180	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
bsdcttw_RS21190	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
bsdcttw_RS21195	COG0438	transferase activity, transferring glycosyl groups
bsdcttw_RS21205	COG2703	oxygen carrier activity
bsdcttw_RS21210	COG1489	DNA binding
bsdcttw_RS21235	COG1132	(ABC) transporter
bsdcttw_RS21255	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
bsdcttw_RS21260	COG1481	regulation of sporulation
bsdcttw_RS21265	COG1660	Displays ATPase and GTPase activities
bsdcttw_RS21270	COG0812	UDP-N-acetylmuramate dehydrogenase activity
bsdcttw_RS21275	COG1940	carbohydrate kinase activity
bsdcttw_RS21280	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
bsdcttw_RS21285	COG0322	excinuclease ABC activity
bsdcttw_RS21290	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
bsdcttw_RS21295	COG0504	CTP synthase activity
bsdcttw_RS21300	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
bsdcttw_RS21305	COG0463	Glycosyl transferase, family 2
bsdcttw_RS21305	COG0457	Tetratricopeptide repeat
bsdcttw_RS21315	COG0438	transferase activity, transferring glycosyl groups
bsdcttw_RS21350	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
bsdcttw_RS21360	COG3475	LICD family
bsdcttw_RS21365	COG1063	alcohol dehydrogenase
bsdcttw_RS21380	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
bsdcttw_RS21390	COG0463	Glycosyl transferase, family 2
bsdcttw_RS21395	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
bsdcttw_RS21410	COG4641	Protein conserved in bacteria
bsdcttw_RS21410	COG1388	LysM domain
bsdcttw_RS21415	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
bsdcttw_RS21425	COG1516	flagellar protein fliS
bsdcttw_RS21430	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
bsdcttw_RS21435	COG1334	flagellar protein FlaG
bsdcttw_RS21440	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
bsdcttw_RS21445	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
bsdcttw_RS21450	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
bsdcttw_RS21460	COG4786	Flagellar basal body rod
bsdcttw_RS21460	COG1256	bacterial-type flagellum assembly
bsdcttw_RS21485	COG1378	Sugar-specific transcriptional regulator TrmB
bsdcttw_RS21490	COG0187	DNA topoisomerase II activity
bsdcttw_RS21495	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
bsdcttw_RS21500	COG1079	Belongs to the binding-protein-dependent transport system permease family
bsdcttw_RS21505	COG4603	Belongs to the binding-protein-dependent transport system permease family
bsdcttw_RS21510	COG3845	ABC transporter
bsdcttw_RS21515	COG1744	ABC transporter substrate-binding protein PnrA-like
bsdcttw_RS21520	COG0813	purine-nucleoside phosphorylase activity
bsdcttw_RS21530	COG1349	DNA-binding transcription factor activity
bsdcttw_RS21540	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
bsdcttw_RS21565	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
bsdcttw_RS21585	COG1196	nuclear chromosome segregation
bsdcttw_RS21585	COG0741	lytic transglycosylase activity
bsdcttw_RS21585	COG0739	heme binding
bsdcttw_RS21590	COG2177	Part of the ABC transporter FtsEX involved in
bsdcttw_RS21595	COG2884	Cell division ATP-binding protein ftsE
bsdcttw_RS21600	COG2508	Transcriptional regulator
bsdcttw_RS21605	COG3842	ATPase activity
bsdcttw_RS21610	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
bsdcttw_RS21640	COG0395	ABC-type sugar transport system, permease component
bsdcttw_RS21645	COG1175	transmembrane transport
bsdcttw_RS21660	COG0423	glycine-tRNA ligase activity
bsdcttw_RS21690	COG2801	Transposase and inactivated derivatives
bsdcttw_RS21695	COG1028	Short-chain dehydrogenase reductase Sdr
bsdcttw_RS21700	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
bsdcttw_RS21710	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
bsdcttw_RS21710	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
bsdcttw_RS21710	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
bsdcttw_RS21715	COG1105	Belongs to the carbohydrate kinase PfkB family
bsdcttw_RS21720	COG1349	DNA-binding transcription factor activity
bsdcttw_RS21740	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
bsdcttw_RS21750	COG0440	acetolactate synthase activity
bsdcttw_RS21755	COG0028	Belongs to the TPP enzyme family
bsdcttw_RS21760	COG3708	Transcriptional regulator
bsdcttw_RS21760	COG2207	Transcriptional regulator
bsdcttw_RS21765	COG2365	Tyrosine phosphatase family
bsdcttw_RS21770	COG0488	(ABC) transporter
bsdcttw_RS21785	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
bsdcttw_RS21830	COG2378	regulation of single-species biofilm formation
bsdcttw_RS21890	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
bsdcttw_RS21935	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
bsdcttw_RS21940	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
bsdcttw_RS21950	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
bsdcttw_RS21955	COG1122	ATPase activity
bsdcttw_RS21960	COG1122	ATPase activity
bsdcttw_RS21970	COG0203	ribosomal protein L17
bsdcttw_RS21975	COG0202	RNA polymerase activity
bsdcttw_RS21980	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
bsdcttw_RS21985	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
bsdcttw_RS21990	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
bsdcttw_RS21995	COG0257	Belongs to the bacterial ribosomal protein bL36 family
bsdcttw_RS22000	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
bsdcttw_RS22015	COG0563	adenylate kinase activity
bsdcttw_RS22020	COG0201	protein transport
bsdcttw_RS22025	COG0200	Binds to the 23S rRNA
bsdcttw_RS22030	COG1841	ribosomal large subunit assembly
bsdcttw_RS22035	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
bsdcttw_RS22040	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
bsdcttw_RS22045	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
bsdcttw_RS22050	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
bsdcttw_RS22055	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
bsdcttw_RS22060	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
bsdcttw_RS22065	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
bsdcttw_RS22070	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
bsdcttw_RS22075	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
bsdcttw_RS22080	COG0255	Belongs to the universal ribosomal protein uL29 family
bsdcttw_RS22085	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
bsdcttw_RS22090	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
bsdcttw_RS22095	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
bsdcttw_RS22100	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
bsdcttw_RS22105	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
bsdcttw_RS22110	COG0089	rRNA binding
bsdcttw_RS22115	COG0088	Forms part of the polypeptide exit tunnel
bsdcttw_RS22120	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
bsdcttw_RS22125	COG0051	transcription antitermination factor activity, RNA binding
bsdcttw_RS22140	COG3279	Response regulator of the LytR AlgR family
bsdcttw_RS22145	COG0116	Belongs to the methyltransferase superfamily
bsdcttw_RS22145	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
bsdcttw_RS22150	COG1609	Transcriptional regulator
bsdcttw_RS22160	COG1842	Phage shock protein A
bsdcttw_RS22165	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
bsdcttw_RS22175	COG4260	virion core protein, lumpy skin disease virus
bsdcttw_RS22180	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
bsdcttw_RS22185	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
bsdcttw_RS22195	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
bsdcttw_RS22205	COG1342	Belongs to the UPF0251 family
bsdcttw_RS22220	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
bsdcttw_RS22230	COG2816	NAD+ diphosphatase activity
bsdcttw_RS22240	COG3546	catalase activity
bsdcttw_RS22300	COG3299	homolog of phage Mu protein gp47
bsdcttw_RS22305	COG3628	GPW Gp25 family protein
bsdcttw_RS22320	COG1652	LysM domain
bsdcttw_RS22465	COG0328	RNA-DNA hybrid ribonuclease activity
bsdcttw_RS22480	COG2002	toxin-antitoxin pair type II binding
bsdcttw_RS22530	COG1193	negative regulation of DNA recombination
bsdcttw_RS22535	COG5002	protein histidine kinase activity
bsdcttw_RS22540	COG0745	RESPONSE REGULATOR receiver
bsdcttw_RS22570	COG0673	inositol 2-dehydrogenase activity
bsdcttw_RS22575	COG2746	aminoglycoside 3-N-acetyltransferase activity
bsdcttw_RS22580	COG0445	tRNA wobble uridine modification
bsdcttw_RS22585	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
bsdcttw_RS22590	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
bsdcttw_RS22590	COG1796	DNA polymerase
bsdcttw_RS22605	COG0395	ABC-type sugar transport system, permease component
bsdcttw_RS22635	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
bsdcttw_RS22645	COG4584	PFAM Integrase catalytic
bsdcttw_RS22665	COG0488	(ABC) transporter
bsdcttw_RS22670	COG0488	(ABC) transporter
bsdcttw_RS22675	COG0488	(ABC) transporter
bsdcttw_RS22680	COG0673	inositol 2-dehydrogenase activity
bsdcttw_RS22700	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
bsdcttw_RS22720	COG0613	PHP domain protein
bsdcttw_RS22845	COG2207	Transcriptional regulator
bsdcttw_RS22860	COG1131	(ABC) transporter
bsdcttw_RS22865	COG0641	radical SAM
bsdcttw_RS22870	COG3119	arylsulfatase activity
bsdcttw_RS22875	COG2197	response regulator
bsdcttw_RS22890	COG1131	(ABC) transporter
bsdcttw_RS22900	COG2207	Transcriptional regulator
bsdcttw_RS22900	COG3708	Transcriptional regulator
bsdcttw_RS22905	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
bsdcttw_RS22920	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
bsdcttw_RS22940	COG0395	ABC-type sugar transport system, permease component
bsdcttw_RS22945	COG4209	transmembrane transport
bsdcttw_RS22950	COG0673	inositol 2-dehydrogenase activity
bsdcttw_RS22975	COG1609	Transcriptional regulator
bsdcttw_RS22980	COG2972	Histidine kinase
bsdcttw_RS22980	COG0745	RESPONSE REGULATOR receiver
bsdcttw_RS22985	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
bsdcttw_RS22990	COG2814	Major facilitator Superfamily
bsdcttw_RS22995	COG2207	Transcriptional regulator
bsdcttw_RS22995	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
bsdcttw_RS23000	COG0018	arginyl-trna synthetase
bsdcttw_RS23005	COG0745	RESPONSE REGULATOR receiver
bsdcttw_RS23010	COG5002	protein histidine kinase activity
bsdcttw_RS23010	COG0642	Histidine kinase
bsdcttw_RS23020	COG0019	diaminopimelate decarboxylase activity
bsdcttw_RS23030	COG1696	Membrane protein involved in D-alanine export
bsdcttw_RS23050	COG3655	Transcriptional regulator
bsdcttw_RS23060	COG3655	Transcriptional regulator
bsdcttw_RS23065	COG0644	oxidoreductase
bsdcttw_RS23090	COG5002	protein histidine kinase activity
bsdcttw_RS23095	COG0745	RESPONSE REGULATOR receiver
bsdcttw_RS23115	COG4716	Myosin-crossreactive antigen
bsdcttw_RS23120	COG4221	oxidoreductase activity
bsdcttw_RS23125	COG1846	Transcriptional regulator
bsdcttw_RS23130	COG5001	Diguanylate cyclase
bsdcttw_RS23150	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
bsdcttw_RS23165	COG3708	Transcriptional regulator
bsdcttw_RS23165	COG2207	Transcriptional regulator
bsdcttw_RS23230	COG4824	toxin secretion phage lysis holin
bsdcttw_RS23315	COG3728	DNA packaging
bsdcttw_RS23315	COG5484	DNA packaging
bsdcttw_RS23480	COG3561	AntA/AntB antirepressor
bsdcttw_RS23515	COG0582	viral genome integration into host DNA
bsdcttw_RS23525	COG3481	metal-dependent phosphohydrolase, HD sub domain
bsdcttw_RS23535	COG1193	negative regulation of DNA recombination
bsdcttw_RS23540	COG0745	RESPONSE REGULATOR receiver
bsdcttw_RS23545	COG5002	protein histidine kinase activity
bsdcttw_RS23555	COG0436	Aminotransferase
bsdcttw_RS23560	COG1522	sequence-specific DNA binding
bsdcttw_RS23570	COG2720	vancomycin resistance protein
bsdcttw_RS23575	COG2176	DNA-directed DNA polymerase activity
bsdcttw_RS23580	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
bsdcttw_RS23585	COG1032	radical SAM domain protein
bsdcttw_RS23610	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
bsdcttw_RS23615	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
bsdcttw_RS23620	COG0037	tRNA processing
bsdcttw_RS23625	COG2208	phosphoserine phosphatase activity
bsdcttw_RS23650	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
bsdcttw_RS23655	COG0776	regulation of translation
bsdcttw_RS23660	COG3956	TIGRFAM MazG family protein
bsdcttw_RS23670	COG2002	toxin-antitoxin pair type II binding
bsdcttw_RS23675	COG0101	tRNA pseudouridine synthase activity
bsdcttw_RS23680	COG0671	phosphoesterase, PA-phosphatase related
bsdcttw_RS23685	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
bsdcttw_RS23690	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
bsdcttw_RS23695	COG0193	aminoacyl-tRNA hydrolase activity
bsdcttw_RS23715	COG2088	sporulation resulting in formation of a cellular spore
bsdcttw_RS23720	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
bsdcttw_RS23725	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
bsdcttw_RS23730	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
bsdcttw_RS23745	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
bsdcttw_RS23755	COG0789	Transcriptional regulator
bsdcttw_RS23760	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
bsdcttw_RS23765	COG4717	serine-type aminopeptidase activity
bsdcttw_RS23780	COG0840	transmembrane signaling receptor activity
bsdcttw_RS23790	COG1705	Flagellar rod assembly protein muramidase FlgJ
bsdcttw_RS23825	COG3299	homolog of phage Mu protein gp47
bsdcttw_RS23830	COG3628	GPW Gp25 family protein
bsdcttw_RS23920	COG1846	Transcriptional regulator
bsdcttw_RS23945	COG1695	Transcriptional regulator
bsdcttw_RS23950	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
bsdcttw_RS23980	COG4129	membrane
bsdcttw_RS23990	COG0017	Asparaginyl-tRNA synthetase
bsdcttw_RS23995	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
bsdcttw_RS24000	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
bsdcttw_RS24065	COG4166	transmembrane transport
bsdcttw_RS24070	COG0601	transmembrane transport
bsdcttw_RS24075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
bsdcttw_RS24080	COG0444	Belongs to the ABC transporter superfamily
bsdcttw_RS24085	COG4608	Belongs to the ABC transporter superfamily
bsdcttw_RS24090	COG2608	mercury ion transmembrane transporter activity
bsdcttw_RS24100	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
bsdcttw_RS24110	COG0395	ABC-type sugar transport system, permease component
bsdcttw_RS24115	COG4209	transmembrane transport
bsdcttw_RS24130	COG0584	glycerophosphoryl diester phosphodiesterase
bsdcttw_RS24135	COG0739	heme binding
bsdcttw_RS24140	COG0840	transmembrane signaling receptor activity
bsdcttw_RS24145	COG0058	SHG alpha-glucan phosphorylase activity
bsdcttw_RS24155	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
bsdcttw_RS24165	COG1335	isochorismatase
bsdcttw_RS24170	COG1733	regulation of RNA biosynthetic process
bsdcttw_RS24180	COG1876	peptidase activity
bsdcttw_RS24185	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
bsdcttw_RS24220	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
bsdcttw_RS24225	COG1181	Belongs to the D-alanine--D-alanine ligase family
bsdcttw_RS24235	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
bsdcttw_RS24250	COG4466	Protein conserved in bacteria
bsdcttw_RS24270	COG0617	tRNA 3'-terminal CCA addition
bsdcttw_RS24335	COG3279	Response regulator of the LytR AlgR family
bsdcttw_RS24340	COG1902	pentaerythritol trinitrate reductase activity
bsdcttw_RS24340	COG0446	pyridine nucleotide-disulphide oxidoreductase
bsdcttw_RS24370	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
bsdcttw_RS24380	COG0237	dephospho-CoA kinase activity
bsdcttw_RS24390	COG0745	RESPONSE REGULATOR receiver
bsdcttw_RS24395	COG5002	protein histidine kinase activity
bsdcttw_RS24400	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
bsdcttw_RS24410	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
bsdcttw_RS24450	COG0590	tRNA wobble adenosine to inosine editing
bsdcttw_RS24475	COG0488	(ABC) transporter
bsdcttw_RS24480	COG1328	CTP reductase activity
bsdcttw_RS24480	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
bsdcttw_RS24485	COG0602	queuosine metabolic process
bsdcttw_RS24495	COG0205	6-phosphofructokinase activity
bsdcttw_RS24500	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
bsdcttw_RS24505	COG0084	hydrolase, TatD family'
bsdcttw_RS24520	COG3546	catalase activity
bsdcttw_RS24545	COG2188	Transcriptional regulator
bsdcttw_RS24575	COG1131	(ABC) transporter
bsdcttw_RS24580	COG0700	Nucleoside recognition
bsdcttw_RS24585	COG2715	membrane protein required for spore maturation
bsdcttw_RS24590	COG2002	toxin-antitoxin pair type II binding
bsdcttw_RS24595	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
bsdcttw_RS24600	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
bsdcttw_RS24605	COG1774	PSP1 C-terminal conserved region
bsdcttw_RS24610	COG0470	DNA polymerase III
bsdcttw_RS24615	COG1728	Protein conserved in bacteria
bsdcttw_RS24620	COG0194	GDP metabolic process
bsdcttw_RS24625	COG1982	Orn Lys Arg decarboxylase major
bsdcttw_RS24645	COG0129	dihydroxy-acid dehydratase activity
bsdcttw_RS24650	COG1122	ATPase activity
bsdcttw_RS24660	COG0310	cobalt ion transport
bsdcttw_RS24665	COG1937	Protein conserved in bacteria
bsdcttw_RS24670	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
bsdcttw_RS24685	COG1091	dTDP-4-dehydrorhamnose reductase activity
bsdcttw_RS24705	COG4106	trans-aconitate 2-methyltransferase activity
bsdcttw_RS24715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
bsdcttw_RS24730	COG3118	belongs to the thioredoxin family
bsdcttw_RS24740	COG0220	tRNA (guanine-N7-)-methyltransferase activity
bsdcttw_RS24755	COG1269	ATP hydrolysis coupled proton transport
bsdcttw_RS24775	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
bsdcttw_RS24780	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
bsdcttw_RS24785	COG1394	ATPase activity, coupled to movement of substances
bsdcttw_RS24790	COG1686	Belongs to the peptidase S11 family
bsdcttw_RS24810	COG1454	alcohol dehydrogenase
bsdcttw_RS24810	COG1012	belongs to the aldehyde dehydrogenase family
bsdcttw_RS24820	COG1475	DNA binding
bsdcttw_RS24825	COG1192	Involved in chromosome partitioning
bsdcttw_RS24845	COG0357	Ribosomal RNA small subunit methyltransferase G
bsdcttw_RS24850	COG0445	tRNA wobble uridine modification
bsdcttw_RS24855	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
bsdcttw_RS24860	COG1847	R3H domain protein
bsdcttw_RS24865	COG0706	membrane insertase activity
bsdcttw_RS24870	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
bsdcttw_RS24875	COG0594	ribonuclease P activity
bsdcttw_RS24880	COG0230	Belongs to the bacterial ribosomal protein bL34 family