locus-tag	class	description
ANAEK_RS00025	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ANAEK_RS00045	COG0247	lactate metabolic process
ANAEK_RS00045	COG2181	nitrate reductase activity
ANAEK_RS00060	COG0189	ligase activity
ANAEK_RS00065	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ANAEK_RS00070	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ANAEK_RS00075	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ANAEK_RS00125	COG3852	Histidine kinase
ANAEK_RS00140	COG0442	prolyl-tRNA aminoacylation
ANAEK_RS00155	COG2249	NAD(P)H dehydrogenase (quinone) activity
ANAEK_RS00180	COG1028	Short-chain dehydrogenase reductase Sdr
ANAEK_RS00195	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ANAEK_RS00205	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
ANAEK_RS00215	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
ANAEK_RS00230	COG0280	phosphate acetyltransferase
ANAEK_RS00235	COG3426	butyrate kinase activity
ANAEK_RS00240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ANAEK_RS00250	COG0586	Pfam SNARE associated Golgi protein
ANAEK_RS00265	COG2086	electron transfer activity
ANAEK_RS00275	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ANAEK_RS00280	COG0861	Integral membrane protein TerC family
ANAEK_RS00300	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ANAEK_RS00300	COG1793	dna ligase
ANAEK_RS00325	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ANAEK_RS00330	COG0805	protein transport
ANAEK_RS00340	COG0183	Belongs to the thiolase family
ANAEK_RS00360	COG1032	radical SAM domain protein
ANAEK_RS00375	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ANAEK_RS00405	COG0352	thiamine-phosphate diphosphorylase activity
ANAEK_RS00410	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ANAEK_RS00415	COG0352	thiamine-phosphate diphosphorylase activity
ANAEK_RS00415	COG0351	phosphomethylpyrimidine kinase
ANAEK_RS00415	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ANAEK_RS00425	COG0305	Participates in initiation and elongation during chromosome replication
ANAEK_RS00445	COG1346	cytolysis
ANAEK_RS00455	COG0583	DNA-binding transcription factor activity
ANAEK_RS00460	COG1410	methionine synthase
ANAEK_RS00460	COG0646	methionine synthase
ANAEK_RS00480	COG0433	COG0433 Predicted ATPase
ANAEK_RS00525	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ANAEK_RS00530	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ANAEK_RS00545	COG0612	Peptidase, M16
ANAEK_RS00550	COG0612	Peptidase, M16
ANAEK_RS00565	COG2204	response regulator
ANAEK_RS00570	COG3852	Histidine kinase
ANAEK_RS00595	COG1077	Cell shape determining protein MreB Mrl
ANAEK_RS00600	COG1077	Cell shape determining protein MreB Mrl
ANAEK_RS00605	COG0823	Involved in the tonB-independent uptake of proteins
ANAEK_RS00605	COG1506	peptidase
ANAEK_RS00625	COG0360	Binds together with S18 to 16S ribosomal RNA
ANAEK_RS00640	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ANAEK_RS00665	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ANAEK_RS00670	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ANAEK_RS00695	COG3706	GGDEF domain
ANAEK_RS00730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ANAEK_RS00730	COG2022	thiamine diphosphate biosynthetic process
ANAEK_RS00740	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ANAEK_RS00755	COG2204	response regulator
ANAEK_RS00765	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
ANAEK_RS00775	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANAEK_RS00775	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ANAEK_RS00790	COG3716	PTS system mannose fructose sorbose family IID component
ANAEK_RS00795	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANAEK_RS00815	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ANAEK_RS00830	COG0662	Cupin 2, conserved barrel domain protein
ANAEK_RS00830	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
ANAEK_RS00840	COG1940	carbohydrate kinase activity
ANAEK_RS00840	COG1846	Transcriptional regulator
ANAEK_RS00845	COG1293	RNA-binding protein homologous to eukaryotic snRNP
ANAEK_RS00890	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ANAEK_RS00930	COG3138	arginine N-succinyltransferase
ANAEK_RS00935	COG1490	D-aminoacyl-tRNA deacylase activity
ANAEK_RS00940	COG0537	adenosine 5'-monophosphoramidase activity
ANAEK_RS00985	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ANAEK_RS00990	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ANAEK_RS00995	COG0463	Glycosyl transferase, family 2
ANAEK_RS01050	COG1612	heme a metabolic process
ANAEK_RS01050	COG0109	protoheme IX farnesyltransferase activity
ANAEK_RS01080	COG2814	Major facilitator Superfamily
ANAEK_RS01105	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ANAEK_RS01120	COG2226	methyltransferase
ANAEK_RS01125	COG0697	spore germination
ANAEK_RS01135	COG0674	pyruvate-flavodoxin oxidoreductase activity
ANAEK_RS01135	COG1013	pyruvate-flavodoxin oxidoreductase activity
ANAEK_RS01135	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ANAEK_RS01180	COG1309	transcriptional regulator
ANAEK_RS01215	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ANAEK_RS01240	COG3070	regulator of competence-specific genes
ANAEK_RS01255	COG1297	OPT oligopeptide transporter protein
ANAEK_RS01260	COG0745	RESPONSE REGULATOR receiver
ANAEK_RS01265	COG2264	protein methyltransferase activity
ANAEK_RS01270	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ANAEK_RS01285	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ANAEK_RS01295	COG1278	Cold shock
ANAEK_RS01310	COG0204	Acyl-transferase
ANAEK_RS01320	COG5002	protein histidine kinase activity
ANAEK_RS01325	COG4770	biotin carboxylase activity
ANAEK_RS01330	COG5016	pyruvate
ANAEK_RS01330	COG0511	ligase activity, forming carbon-carbon bonds
ANAEK_RS01335	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ANAEK_RS01335	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ANAEK_RS01340	COG0484	heat shock protein binding
ANAEK_RS01365	COG0564	pseudouridine synthase activity
ANAEK_RS01370	COG0848	biopolymer transport protein
ANAEK_RS01380	COG0811	peptide transport
ANAEK_RS01420	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ANAEK_RS01420	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ANAEK_RS01425	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ANAEK_RS01430	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ANAEK_RS01435	COG0617	tRNA 3'-terminal CCA addition
ANAEK_RS01440	COG0528	UMP kinase activity
ANAEK_RS01465	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ANAEK_RS01465	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ANAEK_RS01495	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ANAEK_RS01500	COG2062	phosphohistidine phosphatase, SixA
ANAEK_RS01510	COG1640	4-alpha-glucanotransferase
ANAEK_RS01515	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ANAEK_RS01535	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ANAEK_RS01545	COG4191	Histidine kinase
ANAEK_RS01555	COG2839	Protein conserved in bacteria
ANAEK_RS01590	COG1942	4-Oxalocrotonate Tautomerase
ANAEK_RS01600	COG0583	DNA-binding transcription factor activity
ANAEK_RS01660	COG0308	aminopeptidase N
ANAEK_RS01665	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ANAEK_RS01680	COG2151	metal-sulfur cluster biosynthetic enzyme
ANAEK_RS01700	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ANAEK_RS01725	COG4206	TonB-dependent receptor
ANAEK_RS01745	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ANAEK_RS01755	COG0840	transmembrane signaling receptor activity
ANAEK_RS01790	COG0693	protein deglycase activity
ANAEK_RS01810	COG2267	carboxylic ester hydrolase activity
ANAEK_RS01820	COG2855	membrane
ANAEK_RS01825	COG0583	DNA-binding transcription factor activity
ANAEK_RS01840	COG2205	protein histidine kinase activity
ANAEK_RS01845	COG3239	Fatty acid desaturase
ANAEK_RS01850	COG3218	ABC-type transport auxiliary lipoprotein component
ANAEK_RS01860	COG1127	ABC transporter
ANAEK_RS01865	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ANAEK_RS01915	COG1250	3-hydroxyacyl-CoA dehydrogenase
ANAEK_RS01915	COG1024	Enoyl-CoA hydratase
ANAEK_RS01920	COG0183	Belongs to the thiolase family
ANAEK_RS01925	COG1960	acyl-CoA dehydrogenase activity
ANAEK_RS01950	COG2890	protein-(glutamine-N5) methyltransferase activity
ANAEK_RS01960	COG2205	protein histidine kinase activity
ANAEK_RS01960	COG0784	Response regulator, receiver
ANAEK_RS01975	COG0402	S-adenosylhomocysteine deaminase activity
ANAEK_RS01980	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ANAEK_RS01985	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ANAEK_RS01990	COG0163	prenyltransferase activity
ANAEK_RS01995	COG2226	methyltransferase
ANAEK_RS02000	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ANAEK_RS02010	COG0612	Peptidase, M16
ANAEK_RS02050	COG0542	response to heat
ANAEK_RS02055	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ANAEK_RS02070	COG0318	PFAM AMP-dependent synthetase and ligase
ANAEK_RS02130	COG1234	tRNA 3'-trailer cleavage
ANAEK_RS02135	COG1741	Belongs to the pirin family
ANAEK_RS02145	COG1131	(ABC) transporter
ANAEK_RS02160	COG0183	Belongs to the thiolase family
ANAEK_RS02165	COG1250	3-hydroxyacyl-CoA dehydrogenase
ANAEK_RS02165	COG1024	Enoyl-CoA hydratase
ANAEK_RS02175	COG5002	protein histidine kinase activity
ANAEK_RS02180	COG0745	RESPONSE REGULATOR receiver
ANAEK_RS02190	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ANAEK_RS02215	COG3852	Histidine kinase
ANAEK_RS02225	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ANAEK_RS02230	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ANAEK_RS02240	COG1088	dTDP-glucose 4,6-dehydratase activity
ANAEK_RS02245	COG0204	Acyl-transferase
ANAEK_RS02255	COG1846	Transcriptional regulator
ANAEK_RS02270	COG3706	GGDEF domain
ANAEK_RS02310	COG0420	3'-5' exonuclease activity
ANAEK_RS02345	COG0577	efflux transmembrane transporter activity
ANAEK_RS02345	COG1136	(ABC) transporter
ANAEK_RS02380	COG1309	transcriptional regulator
ANAEK_RS02390	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
ANAEK_RS02400	COG0667	Aldo Keto reductase
ANAEK_RS02420	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ANAEK_RS02420	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ANAEK_RS02425	COG3639	organic phosphonate transmembrane transporter activity
ANAEK_RS02430	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
ANAEK_RS02450	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ANAEK_RS02455	COG0439	Biotin carboxylase
ANAEK_RS02475	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ANAEK_RS02480	COG3875	lactate racemase activity
ANAEK_RS02510	COG0298	carbon dioxide binding
ANAEK_RS02515	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
ANAEK_RS02525	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
ANAEK_RS02530	COG5557	Pfam Polysulphide reductase, NrfD
ANAEK_RS02535	COG0437	4 iron, 4 sulfur cluster binding
ANAEK_RS02540	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
ANAEK_RS02570	COG1285	pathogenesis
ANAEK_RS02575	COG2119	membrane
ANAEK_RS02600	COG1122	ATPase activity
ANAEK_RS02610	COG0310	cobalt ion transport
ANAEK_RS02625	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ANAEK_RS02625	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ANAEK_RS02650	COG2205	protein histidine kinase activity
ANAEK_RS02665	COG5002	protein histidine kinase activity
ANAEK_RS02670	COG0493	'glutamate synthase
ANAEK_RS02670	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
ANAEK_RS02675	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ANAEK_RS02675	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ANAEK_RS02680	COG2133	pyrroloquinoline quinone binding
ANAEK_RS02685	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ANAEK_RS02720	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ANAEK_RS02730	COG1309	transcriptional regulator
ANAEK_RS02735	COG0366	Alpha amylase catalytic
ANAEK_RS02745	COG0596	Alpha beta hydrolase
ANAEK_RS02755	COG2832	Protein of unknown function (DUF454)
ANAEK_RS02780	COG0671	phosphoesterase, PA-phosphatase related
ANAEK_RS02785	COG1752	Esterase of the alpha-beta hydrolase superfamily
ANAEK_RS02795	COG0436	Aminotransferase
ANAEK_RS02805	COG3047	cAMP biosynthetic process
ANAEK_RS02810	COG4191	Histidine kinase
ANAEK_RS02820	COG1122	ATPase activity
ANAEK_RS02825	COG1268	BioY protein
ANAEK_RS02830	COG0400	carboxylic ester hydrolase activity
ANAEK_RS02855	COG0667	Aldo Keto reductase
ANAEK_RS02885	COG0583	DNA-binding transcription factor activity
ANAEK_RS02895	COG1028	Short-chain dehydrogenase reductase Sdr
ANAEK_RS02920	COG1028	Short-chain dehydrogenase reductase Sdr
ANAEK_RS02925	COG0583	DNA-binding transcription factor activity
ANAEK_RS02975	COG3177	Filamentation induced by cAMP protein fic
ANAEK_RS02990	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ANAEK_RS03000	COG1228	amidohydrolase
ANAEK_RS03005	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ANAEK_RS03010	COG2204	response regulator
ANAEK_RS03035	COG0612	Peptidase, M16
ANAEK_RS03040	COG5002	protein histidine kinase activity
ANAEK_RS03090	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ANAEK_RS03095	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ANAEK_RS03115	COG4232	protein-disulfide reductase activity
ANAEK_RS03130	COG0316	Belongs to the HesB IscA family
ANAEK_RS03135	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ANAEK_RS03140	COG0443	Heat shock 70 kDa protein
ANAEK_RS03155	COG2201	protein-glutamate methylesterase activity
ANAEK_RS03165	COG0835	chemotaxis
ANAEK_RS03170	COG0643	Histidine kinase
ANAEK_RS03170	COG2198	Histidine kinase
ANAEK_RS03175	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ANAEK_RS03185	COG0745	RESPONSE REGULATOR receiver
ANAEK_RS03200	COG0745	RESPONSE REGULATOR receiver
ANAEK_RS03225	COG2201	protein-glutamate methylesterase activity
ANAEK_RS03235	COG0784	Response regulator, receiver
ANAEK_RS03240	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
ANAEK_RS03245	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ANAEK_RS03255	COG0295	cytidine deaminase activity
ANAEK_RS03260	COG0196	riboflavin kinase activity
ANAEK_RS03265	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ANAEK_RS03275	COG1459	type II secretion system
ANAEK_RS03280	COG3852	Histidine kinase
ANAEK_RS03330	COG4968	Prepilin-type N-terminal cleavage methylation domain
ANAEK_RS03335	COG1131	(ABC) transporter
ANAEK_RS03340	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ANAEK_RS03345	COG4191	Histidine kinase
ANAEK_RS03350	COG2204	response regulator
ANAEK_RS03395	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ANAEK_RS03400	COG0511	ligase activity, forming carbon-carbon bonds
ANAEK_RS03405	COG0439	Biotin carboxylase
ANAEK_RS03415	COG3409	Peptidoglycan-binding domain 1 protein
ANAEK_RS03415	COG3267	Type II secretory pathway component ExeA
ANAEK_RS03430	COG2217	Heavy metal translocating P-type atpase
ANAEK_RS03475	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ANAEK_RS03485	COG2884	Cell division ATP-binding protein ftsE
ANAEK_RS03490	COG2177	Part of the ABC transporter FtsEX involved in
ANAEK_RS03495	COG4942	peptidase
ANAEK_RS03500	COG0793	Belongs to the peptidase S41A family
ANAEK_RS03505	COG1215	transferase activity, transferring glycosyl groups
ANAEK_RS03515	COG0546	phosphoglycolate phosphatase activity
ANAEK_RS03520	COG0552	protein localization to endoplasmic reticulum
ANAEK_RS03525	COG1196	nuclear chromosome segregation
ANAEK_RS03530	COG0840	transmembrane signaling receptor activity
ANAEK_RS03530	COG3290	protein histidine kinase activity
ANAEK_RS03565	COG2165	general secretion pathway protein
ANAEK_RS03575	COG1459	type II secretion system
ANAEK_RS03580	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ANAEK_RS03585	COG1450	Type ii and iii secretion system protein
ANAEK_RS03605	COG0254	rRNA binding
ANAEK_RS03610	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ANAEK_RS03630	COG1254	Belongs to the acylphosphatase family
ANAEK_RS03640	COG1530	ribonuclease E activity
ANAEK_RS03640	COG1530	ribonuclease E activity
ANAEK_RS03645	COG1295	ribonuclease BN
ANAEK_RS03650	COG0776	regulation of translation
ANAEK_RS03655	COG4789	Type iii secretion
ANAEK_RS03660	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ANAEK_RS03670	COG4794	Type iii secretion
ANAEK_RS03720	COG2197	response regulator
ANAEK_RS03725	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ANAEK_RS03735	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ANAEK_RS03745	COG0107	imidazoleglycerol-phosphate synthase activity
ANAEK_RS03790	COG1584	GPR1 FUN34 yaaH family protein
ANAEK_RS03795	COG0242	peptide deformylase activity
ANAEK_RS03810	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ANAEK_RS03825	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ANAEK_RS03830	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ANAEK_RS03835	COG0497	DNA recombination
ANAEK_RS03840	COG0631	protein serine/threonine phosphatase activity
ANAEK_RS03845	COG0739	heme binding
ANAEK_RS03855	COG0653	protein targeting
ANAEK_RS03880	COG1203	CRISPR-associated helicase, Cas3
ANAEK_RS03910	COG1518	maintenance of DNA repeat elements
ANAEK_RS03935	COG1595	DNA-templated transcription, initiation
ANAEK_RS03960	COG0628	permease
ANAEK_RS03975	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ANAEK_RS03985	COG0739	heme binding
ANAEK_RS04005	COG1881	PFAM PEBP family protein
ANAEK_RS04020	COG0348	domain, Protein
ANAEK_RS04030	COG0589	response to stress
ANAEK_RS04035	COG0167	dihydroorotate dehydrogenase activity
ANAEK_RS04055	COG0247	lactate metabolic process
ANAEK_RS04065	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ANAEK_RS04105	COG0745	RESPONSE REGULATOR receiver
ANAEK_RS04115	COG1253	flavin adenine dinucleotide binding
ANAEK_RS04125	COG2264	protein methyltransferase activity
ANAEK_RS04135	COG0508	dehydrogenase complex catalyzes the overall conversion of
ANAEK_RS04160	COG1643	Atp-dependent helicase
ANAEK_RS04165	COG0071	Belongs to the small heat shock protein (HSP20) family
ANAEK_RS04175	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ANAEK_RS04195	COG1595	DNA-templated transcription, initiation
ANAEK_RS04205	COG0437	4 iron, 4 sulfur cluster binding
ANAEK_RS04240	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ANAEK_RS04265	COG0028	Belongs to the TPP enzyme family
ANAEK_RS04270	COG4948	Mandelate Racemase Muconate Lactonizing
ANAEK_RS04275	COG0247	lactate metabolic process
ANAEK_RS04275	COG0277	FAD linked oxidase domain protein
ANAEK_RS04280	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ANAEK_RS04290	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ANAEK_RS04305	COG1793	dna ligase
ANAEK_RS04310	COG0067	glutamate synthase
ANAEK_RS04310	COG0069	glutamate synthase activity
ANAEK_RS04310	COG0070	glutamate synthase
ANAEK_RS04315	COG0493	'glutamate synthase
ANAEK_RS04330	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ANAEK_RS04340	COG0437	4 iron, 4 sulfur cluster binding
ANAEK_RS04345	COG0243	molybdopterin cofactor binding
ANAEK_RS04345	COG3383	formate dehydrogenase (NAD+) activity
ANAEK_RS04350	COG0243	molybdopterin cofactor binding
ANAEK_RS04360	COG3973	AAA domain
ANAEK_RS04365	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ANAEK_RS04370	COG0488	(ABC) transporter
ANAEK_RS04375	COG1012	belongs to the aldehyde dehydrogenase family
ANAEK_RS04390	COG4191	Histidine kinase
ANAEK_RS04395	COG1131	(ABC) transporter
ANAEK_RS04400	COG0842	Transport permease protein
ANAEK_RS04410	COG0514	ATP-dependent DNA helicase (RecQ)
ANAEK_RS04425	COG4681	YaeQ
ANAEK_RS04435	COG0719	Fe-S assembly protein
ANAEK_RS04440	COG0396	ATPase activity
ANAEK_RS04445	COG0719	Fe-S assembly protein
ANAEK_RS04450	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ANAEK_RS04475	COG0793	Belongs to the peptidase S41A family
ANAEK_RS04485	COG1136	(ABC) transporter
ANAEK_RS04485	COG0577	efflux transmembrane transporter activity
ANAEK_RS04490	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ANAEK_RS04500	COG2197	response regulator
ANAEK_RS04535	COG0058	SHG alpha-glucan phosphorylase activity
ANAEK_RS04545	COG1704	LemA family
ANAEK_RS04570	COG1396	sequence-specific DNA binding
ANAEK_RS04575	COG0745	RESPONSE REGULATOR receiver
ANAEK_RS04580	COG0004	ammonium transporteR
ANAEK_RS04660	COG0668	transmembrane transport
ANAEK_RS04685	COG0745	RESPONSE REGULATOR receiver
ANAEK_RS04690	COG2205	protein histidine kinase activity
ANAEK_RS04700	COG0531	amino acid
ANAEK_RS04725	COG2322	membrane
ANAEK_RS04740	COG0109	protoheme IX farnesyltransferase activity
ANAEK_RS04755	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ANAEK_RS04770	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
ANAEK_RS04780	COG0243	molybdopterin cofactor binding
ANAEK_RS04790	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
ANAEK_RS04800	COG2132	Multicopper oxidase
ANAEK_RS04855	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ANAEK_RS04860	COG0830	nickel cation binding
ANAEK_RS04870	COG0832	Belongs to the urease beta subunit family
ANAEK_RS04870	COG0831	urea catabolic process
ANAEK_RS04875	COG0829	nickel cation binding
ANAEK_RS04885	COG4191	Histidine kinase
ANAEK_RS04905	COG2873	o-acetylhomoserine
ANAEK_RS04920	COG0432	Pfam Uncharacterised protein family UPF0047
ANAEK_RS04925	COG0003	Pfam Anion-transporting ATPase
ANAEK_RS04940	COG1192	Involved in chromosome partitioning
ANAEK_RS04955	COG3384	dioxygenase
ANAEK_RS04960	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
ANAEK_RS04975	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ANAEK_RS04980	COG0584	glycerophosphoryl diester phosphodiesterase
ANAEK_RS04990	COG1271	oxidase subunit
ANAEK_RS04995	COG1294	oxidase, subunit
ANAEK_RS05010	COG1331	Highly conserved protein containing a thioredoxin domain
ANAEK_RS05045	COG2814	Major facilitator Superfamily
ANAEK_RS05070	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ANAEK_RS05105	COG1793	dna ligase
ANAEK_RS05105	COG3285	dna ligase
ANAEK_RS05120	COG0427	acetyl-CoA hydrolase
ANAEK_RS05130	COG0745	RESPONSE REGULATOR receiver
ANAEK_RS05140	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ANAEK_RS05175	COG2814	Major facilitator Superfamily
ANAEK_RS05195	COG4783	chaperone-mediated protein folding
ANAEK_RS05210	COG1278	Cold shock
ANAEK_RS05225	COG1720	tRNA m6t6A37 methyltransferase activity
ANAEK_RS05265	COG3842	ATPase activity
ANAEK_RS05295	COG4603	Belongs to the binding-protein-dependent transport system permease family
ANAEK_RS05300	COG1129	ABC transporter
ANAEK_RS05305	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
ANAEK_RS05360	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ANAEK_RS05385	COG3239	Fatty acid desaturase
ANAEK_RS05420	COG1309	transcriptional regulator
ANAEK_RS05455	COG1335	isochorismatase
ANAEK_RS05460	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ANAEK_RS05475	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ANAEK_RS05485	COG1692	metallophosphoesterase
ANAEK_RS05500	COG1104	cysteine desulfurase activity
ANAEK_RS05510	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ANAEK_RS05530	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ANAEK_RS05550	COG2204	response regulator
ANAEK_RS05580	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ANAEK_RS05590	COG0673	inositol 2-dehydrogenase activity
ANAEK_RS05610	COG1132	(ABC) transporter
ANAEK_RS05620	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ANAEK_RS05625	COG4221	oxidoreductase activity
ANAEK_RS05630	COG5000	phosphorelay sensor kinase activity
ANAEK_RS05655	COG1543	Belongs to the glycosyl hydrolase 57 family
ANAEK_RS05675	COG1136	(ABC) transporter
ANAEK_RS05680	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ANAEK_RS05705	COG3494	Protein of unknown function (DUF1009)
ANAEK_RS05715	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ANAEK_RS05720	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ANAEK_RS05725	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ANAEK_RS05735	COG0484	heat shock protein binding
ANAEK_RS05745	COG1570	exodeoxyribonuclease VII activity
ANAEK_RS05750	COG1722	exodeoxyribonuclease VII activity
ANAEK_RS05755	COG0745	RESPONSE REGULATOR receiver
ANAEK_RS05760	COG0142	geranyltranstransferase activity
ANAEK_RS05770	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
ANAEK_RS05805	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ANAEK_RS05825	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ANAEK_RS05835	COG5002	protein histidine kinase activity
ANAEK_RS05855	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ANAEK_RS05865	COG0546	phosphoglycolate phosphatase activity
ANAEK_RS05875	COG0745	RESPONSE REGULATOR receiver
ANAEK_RS05885	COG0750	zinc metalloprotease
ANAEK_RS05890	COG2078	PFAM AMMECR1 domain protein
ANAEK_RS05895	COG2816	NAD+ diphosphatase activity
ANAEK_RS05930	COG5002	protein histidine kinase activity
ANAEK_RS05940	COG1960	acyl-CoA dehydrogenase activity
ANAEK_RS05945	COG1324	tolerance protein
ANAEK_RS05955	COG0515	serine threonine protein kinase
ANAEK_RS05965	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ANAEK_RS05970	COG0616	signal peptide processing
ANAEK_RS05975	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
ANAEK_RS05980	COG1607	acyl-coa hydrolase
ANAEK_RS06000	COG1408	metallophosphoesterase
ANAEK_RS06010	COG0450	alkyl hydroperoxide reductase
ANAEK_RS06025	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ANAEK_RS06030	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
ANAEK_RS06055	COG1100	Small GTP-binding protein
ANAEK_RS06065	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ANAEK_RS06085	COG2226	methyltransferase
ANAEK_RS06090	COG0840	transmembrane signaling receptor activity
ANAEK_RS06095	COG1064	alcohol dehydrogenase
ANAEK_RS06110	COG0318	PFAM AMP-dependent synthetase and ligase
ANAEK_RS06115	COG3875	lactate racemase activity
ANAEK_RS06135	COG0243	molybdopterin cofactor binding
ANAEK_RS06140	COG3278	Belongs to the heme-copper respiratory oxidase family
ANAEK_RS06155	COG0348	domain, Protein
ANAEK_RS06170	COG2217	Heavy metal translocating P-type atpase
ANAEK_RS06180	COG1049	propionate catabolic process, 2-methylcitrate cycle
ANAEK_RS06230	COG0114	fumarate hydratase activity
ANAEK_RS06260	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ANAEK_RS06285	COG1355	regulation of microtubule-based process
ANAEK_RS06305	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ANAEK_RS06315	COG0443	Heat shock 70 kDa protein
ANAEK_RS06320	COG0484	heat shock protein binding
ANAEK_RS06330	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ANAEK_RS06335	COG0010	Belongs to the arginase family
ANAEK_RS06340	COG1959	2 iron, 2 sulfur cluster binding
ANAEK_RS06345	COG0613	PHP domain protein
ANAEK_RS06350	COG1007	ATP synthesis coupled electron transport
ANAEK_RS06365	COG0713	ATP synthesis coupled electron transport
ANAEK_RS06375	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ANAEK_RS06380	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ANAEK_RS06390	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ANAEK_RS06400	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ANAEK_RS06415	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ANAEK_RS06430	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ANAEK_RS06435	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ANAEK_RS06450	COG2223	nitrite transmembrane transporter activity
ANAEK_RS06455	COG1796	DNA polymerase
ANAEK_RS06455	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ANAEK_RS06465	COG0521	Mo-molybdopterin cofactor biosynthetic process
ANAEK_RS06530	COG0586	Pfam SNARE associated Golgi protein
ANAEK_RS06535	COG2385	sporulation resulting in formation of a cellular spore
ANAEK_RS06550	COG0343	queuine tRNA-ribosyltransferase activity
ANAEK_RS06555	COG1862	Preprotein translocase
ANAEK_RS06560	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ANAEK_RS06565	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ANAEK_RS06580	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ANAEK_RS06580	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ANAEK_RS06585	COG0604	alcohol dehydrogenase
ANAEK_RS06600	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ANAEK_RS06625	COG1597	lipid kinase activity
ANAEK_RS06660	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ANAEK_RS06665	COG0612	Peptidase, M16
ANAEK_RS06680	COG0783	Belongs to the Dps family
ANAEK_RS06700	COG0352	thiamine-phosphate diphosphorylase activity
ANAEK_RS06720	COG1074	ATP-dependent DNA helicase activity
ANAEK_RS06735	COG1830	Aldolase
ANAEK_RS06775	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ANAEK_RS06785	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ANAEK_RS06800	COG0768	penicillin binding
ANAEK_RS06805	COG0772	Belongs to the SEDS family
ANAEK_RS06810	COG3118	belongs to the thioredoxin family
ANAEK_RS06825	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ANAEK_RS06830	COG0181	hydroxymethylbilane synthase activity
ANAEK_RS06845	COG0585	pseudouridine synthase activity
ANAEK_RS06850	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ANAEK_RS06865	COG0587	DNA-directed DNA polymerase activity
ANAEK_RS06905	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ANAEK_RS06910	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ANAEK_RS06915	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ANAEK_RS06915	COG0446	pyridine nucleotide-disulphide oxidoreductase
ANAEK_RS06930	COG0312	modulator of DNA gyrase
ANAEK_RS06965	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ANAEK_RS07020	COG1216	Glycosyl transferase, family 2
ANAEK_RS07035	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ANAEK_RS07040	COG0009	L-threonylcarbamoyladenylate synthase
ANAEK_RS07050	COG0113	porphobilinogen synthase activity
ANAEK_RS07065	COG1181	Belongs to the D-alanine--D-alanine ligase family
ANAEK_RS07105	COG0784	Response regulator, receiver
ANAEK_RS07105	COG2205	protein histidine kinase activity
ANAEK_RS07160	COG0745	RESPONSE REGULATOR receiver
ANAEK_RS07175	COG0557	exoribonuclease II activity
ANAEK_RS07185	COG0730	response to heat
ANAEK_RS07190	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
ANAEK_RS07200	COG0411	ABC transporter
ANAEK_RS07225	COG1193	negative regulation of DNA recombination
ANAEK_RS07260	COG1595	DNA-templated transcription, initiation
ANAEK_RS07280	COG3876	Protein conserved in bacteria
ANAEK_RS07300	COG0542	response to heat
ANAEK_RS07325	COG4263	nitrous-oxide reductase activity
ANAEK_RS07355	COG1752	Esterase of the alpha-beta hydrolase superfamily
ANAEK_RS07370	COG0459	protein refolding
ANAEK_RS07375	COG3706	GGDEF domain
ANAEK_RS07390	COG0525	valine-tRNA ligase activity
ANAEK_RS07400	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ANAEK_RS07400	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ANAEK_RS07450	COG1595	DNA-templated transcription, initiation
ANAEK_RS07460	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ANAEK_RS07480	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ANAEK_RS07490	COG1573	uracil-dna glycosylase
ANAEK_RS07500	COG0330	HflC and HflK could
ANAEK_RS07515	COG0183	Belongs to the thiolase family
ANAEK_RS07520	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ANAEK_RS07540	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ANAEK_RS07580	COG0501	Belongs to the peptidase M48B family
ANAEK_RS07600	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ANAEK_RS07610	COG0586	Pfam SNARE associated Golgi protein
ANAEK_RS07615	COG0443	Heat shock 70 kDa protein
ANAEK_RS07620	COG0516	GMP reductase activity
ANAEK_RS07620	COG0517	IMP dehydrogenase activity
ANAEK_RS07625	COG0519	Catalyzes the synthesis of GMP from XMP
ANAEK_RS07625	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ANAEK_RS07645	COG0745	RESPONSE REGULATOR receiver
ANAEK_RS07645	COG4566	intracellular signal transduction
ANAEK_RS07655	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ANAEK_RS07665	COG3746	phosphate-selective porin O and P
ANAEK_RS07675	COG1121	(ABC) transporter
ANAEK_RS07700	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
ANAEK_RS07770	COG2801	Transposase and inactivated derivatives
ANAEK_RS07780	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ANAEK_RS07785	COG2985	domain, Protein
ANAEK_RS07785	COG0569	domain protein
ANAEK_RS07815	COG0436	Aminotransferase
ANAEK_RS07825	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ANAEK_RS07835	COG1028	Short-chain dehydrogenase reductase Sdr
ANAEK_RS07835	COG3347	Dehydrogenase
ANAEK_RS07845	COG0509	glycine decarboxylation via glycine cleavage system
ANAEK_RS07850	COG0300	oxidoreductase activity
ANAEK_RS07855	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ANAEK_RS07855	COG5322	oxidoreductase activity
ANAEK_RS07860	COG0243	molybdopterin cofactor binding
ANAEK_RS07915	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ANAEK_RS07930	COG2814	Major facilitator Superfamily
ANAEK_RS07940	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ANAEK_RS07970	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ANAEK_RS08000	COG2010	Cytochrome c
ANAEK_RS08005	COG0737	Belongs to the 5'-nucleotidase family
ANAEK_RS08030	COG1845	cytochrome c oxidase, subunit III
ANAEK_RS08030	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ANAEK_RS08050	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ANAEK_RS08095	COG4651	solute:proton antiporter activity
ANAEK_RS08095	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ANAEK_RS08100	COG0443	Heat shock 70 kDa protein
ANAEK_RS08125	COG0392	lysyltransferase activity
ANAEK_RS08125	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
ANAEK_RS08140	COG1595	DNA-templated transcription, initiation
ANAEK_RS08175	COG2259	Doxx family
ANAEK_RS08200	COG2204	response regulator
ANAEK_RS08215	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ANAEK_RS08260	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ANAEK_RS08270	COG0039	L-malate dehydrogenase activity
ANAEK_RS08295	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ANAEK_RS08295	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ANAEK_RS08305	COG0004	ammonium transporteR
ANAEK_RS08330	COG2814	Major facilitator Superfamily
ANAEK_RS08335	COG0583	DNA-binding transcription factor activity
ANAEK_RS08345	COG2205	protein histidine kinase activity
ANAEK_RS08350	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ANAEK_RS08360	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ANAEK_RS08365	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ANAEK_RS08370	COG1741	Belongs to the pirin family
ANAEK_RS08395	COG0583	DNA-binding transcription factor activity
ANAEK_RS08400	COG3118	belongs to the thioredoxin family
ANAEK_RS08425	COG0583	DNA-binding transcription factor activity
ANAEK_RS08440	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ANAEK_RS08445	COG1592	Rubrerythrin
ANAEK_RS08450	COG2205	protein histidine kinase activity
ANAEK_RS08480	COG0840	transmembrane signaling receptor activity
ANAEK_RS08485	COG0835	chemotaxis
ANAEK_RS08525	COG0730	response to heat
ANAEK_RS08535	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
ANAEK_RS08545	COG2223	nitrite transmembrane transporter activity
ANAEK_RS08560	COG1140	nitrate reductase beta subunit
ANAEK_RS08565	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
ANAEK_RS08575	COG4191	Histidine kinase
ANAEK_RS08615	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ANAEK_RS08625	COG0488	(ABC) transporter
ANAEK_RS08640	COG2818	Glycosylase
ANAEK_RS08645	COG1252	NADH dehydrogenase
ANAEK_RS08650	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ANAEK_RS08660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ANAEK_RS08660	COG4191	Histidine kinase
ANAEK_RS08695	COG0785	Cytochrome C biogenesis protein
ANAEK_RS08710	COG2814	Major facilitator Superfamily
ANAEK_RS08715	COG0252	asparaginase activity
ANAEK_RS08730	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
ANAEK_RS08740	COG0508	dehydrogenase complex catalyzes the overall conversion of
ANAEK_RS08745	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ANAEK_RS08790	COG1595	DNA-templated transcription, initiation
ANAEK_RS08795	COG0667	Aldo Keto reductase
ANAEK_RS08830	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ANAEK_RS08840	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ANAEK_RS08855	COG0686	Belongs to the AlaDH PNT family
ANAEK_RS08860	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ANAEK_RS08865	COG2226	methyltransferase
ANAEK_RS08870	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ANAEK_RS08885	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ANAEK_RS08890	COG4191	Histidine kinase
ANAEK_RS08890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ANAEK_RS08895	COG2204	response regulator
ANAEK_RS08925	COG1053	succinate dehydrogenase
ANAEK_RS08935	COG0156	8-amino-7-oxononanoate synthase activity
ANAEK_RS08945	COG1201	RNA secondary structure unwinding
ANAEK_RS08950	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ANAEK_RS08955	COG0784	Response regulator, receiver
ANAEK_RS08955	COG2205	protein histidine kinase activity
ANAEK_RS08965	COG3383	formate dehydrogenase (NAD+) activity
ANAEK_RS08965	COG0243	molybdopterin cofactor binding
ANAEK_RS08970	COG0437	4 iron, 4 sulfur cluster binding
ANAEK_RS08970	COG3064	Membrane
ANAEK_RS08975	COG3058	Necessary for formate dehydrogenase activity
ANAEK_RS08985	COG0626	cystathionine gamma-synthase activity
ANAEK_RS09010	COG2195	Cleaves the N-terminal amino acid of tripeptides
ANAEK_RS09025	COG0667	Aldo Keto reductase
ANAEK_RS09050	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ANAEK_RS09055	COG0473	3-isopropylmalate dehydrogenase activity
ANAEK_RS09060	COG2755	lipolytic protein G-D-S-L family
ANAEK_RS09060	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ANAEK_RS09065	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ANAEK_RS09065	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ANAEK_RS09100	COG0488	(ABC) transporter
ANAEK_RS09115	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ANAEK_RS09125	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ANAEK_RS09135	COG1164	Oligoendopeptidase f
ANAEK_RS09155	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
ANAEK_RS09170	COG0351	phosphomethylpyrimidine kinase
ANAEK_RS09180	COG2095	MarC family integral membrane protein
ANAEK_RS09195	COG1136	(ABC) transporter
ANAEK_RS09200	COG0577	efflux transmembrane transporter activity
ANAEK_RS09215	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
ANAEK_RS09225	COG2373	Large extracellular alpha-helical protein
ANAEK_RS09230	COG4953	penicillin-binding protein 1C
ANAEK_RS09270	COG0656	L-ascorbic acid biosynthetic process
ANAEK_RS09300	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ANAEK_RS09320	COG0501	Belongs to the peptidase M48B family
ANAEK_RS09325	COG0583	DNA-binding transcription factor activity
ANAEK_RS09340	COG0408	coproporphyrinogen oxidase activity
ANAEK_RS09350	COG0788	formyltetrahydrofolate deformylase activity
ANAEK_RS09365	COG2204	response regulator
ANAEK_RS09375	COG3064	Membrane
ANAEK_RS09375	COG0437	4 iron, 4 sulfur cluster binding
ANAEK_RS09380	COG5557	Pfam Polysulphide reductase, NrfD
ANAEK_RS09385	COG0509	glycine decarboxylation via glycine cleavage system
ANAEK_RS09420	COG4585	Histidine kinase
ANAEK_RS09425	COG2197	response regulator
ANAEK_RS09440	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ANAEK_RS09445	COG4191	Histidine kinase
ANAEK_RS09450	COG2204	response regulator
ANAEK_RS09455	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ANAEK_RS09475	COG1217	gtp-binding protein TYPA
ANAEK_RS09490	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ANAEK_RS09510	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ANAEK_RS09555	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ANAEK_RS09560	COG0072	phenylalanine-tRNA ligase activity
ANAEK_RS09580	COG2146	nitrite reductase [NAD(P)H] activity
ANAEK_RS09585	COG0720	synthase
ANAEK_RS09590	COG0302	gtp cyclohydrolase
ANAEK_RS09595	COG1028	Short-chain dehydrogenase reductase Sdr
ANAEK_RS09600	COG0277	FAD linked oxidase domain protein
ANAEK_RS09605	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ANAEK_RS09605	COG0674	pyruvate-flavodoxin oxidoreductase activity
ANAEK_RS09610	COG1013	pyruvate-flavodoxin oxidoreductase activity
ANAEK_RS09620	COG0674	pyruvate-flavodoxin oxidoreductase activity
ANAEK_RS09620	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ANAEK_RS09625	COG1013	pyruvate-flavodoxin oxidoreductase activity
ANAEK_RS09645	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ANAEK_RS09655	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ANAEK_RS09660	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ANAEK_RS09680	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ANAEK_RS09685	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ANAEK_RS09690	COG0051	transcription antitermination factor activity, RNA binding
ANAEK_RS09730	COG0255	Belongs to the universal ribosomal protein uL29 family
ANAEK_RS09775	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ANAEK_RS09790	COG0201	protein transport
ANAEK_RS09805	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ANAEK_RS09815	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ANAEK_RS09845	COG1837	Belongs to the UPF0109 family
ANAEK_RS09850	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ANAEK_RS09870	COG0792	nuclease activity
ANAEK_RS09875	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ANAEK_RS09885	COG3852	Histidine kinase
ANAEK_RS09890	COG0741	lytic transglycosylase activity
ANAEK_RS09915	COG0564	pseudouridine synthase activity
ANAEK_RS09930	COG2226	methyltransferase
ANAEK_RS09940	COG1166	arginine decarboxylase activity
ANAEK_RS09960	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ANAEK_RS10005	COG0564	pseudouridine synthase activity
ANAEK_RS10015	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ANAEK_RS10020	COG1127	ABC transporter
ANAEK_RS10030	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ANAEK_RS10040	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ANAEK_RS10070	COG1024	Enoyl-CoA hydratase
ANAEK_RS10075	COG2205	protein histidine kinase activity
ANAEK_RS10160	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ANAEK_RS10160	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ANAEK_RS10170	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ANAEK_RS10180	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ANAEK_RS10190	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ANAEK_RS10195	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ANAEK_RS10200	COG0022	dehydrogenase e1 component
ANAEK_RS10215	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ANAEK_RS10220	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ANAEK_RS10235	COG1297	OPT oligopeptide transporter protein
ANAEK_RS10255	COG0527	aspartate kinase activity
ANAEK_RS10280	COG1574	metal-dependent hydrolase with the TIM-barrel fold
ANAEK_RS10290	COG0210	DNA helicase
ANAEK_RS10295	COG0443	Heat shock 70 kDa protein
ANAEK_RS10330	COG2205	protein histidine kinase activity
ANAEK_RS10360	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ANAEK_RS10380	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ANAEK_RS10385	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ANAEK_RS10410	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ANAEK_RS10430	COG2197	response regulator
ANAEK_RS10445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ANAEK_RS10445	COG4191	Histidine kinase
ANAEK_RS10450	COG2204	response regulator
ANAEK_RS10455	COG1027	Aspartate ammonia-lyase
ANAEK_RS10460	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ANAEK_RS10465	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
ANAEK_RS10495	COG5654	RES domain protein
ANAEK_RS10525	COG0464	growth
ANAEK_RS10575	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ANAEK_RS10580	COG4208	sulfate ABC transporter
ANAEK_RS10590	COG0175	sulfate reduction
ANAEK_RS10595	COG2895	sulfate adenylyltransferase (ATP) activity
ANAEK_RS10600	COG0175	sulfate reduction
ANAEK_RS10610	COG0742	ribosomal rna small subunit methyltransferase
ANAEK_RS10630	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ANAEK_RS10640	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ANAEK_RS10655	COG0436	Aminotransferase
ANAEK_RS10670	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ANAEK_RS10675	COG1058	Belongs to the CinA family
ANAEK_RS10675	COG1546	Belongs to the CinA family
ANAEK_RS10720	COG2204	response regulator
ANAEK_RS10730	COG0515	serine threonine protein kinase
ANAEK_RS10730	COG2815	serine threonine protein kinase
ANAEK_RS10740	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ANAEK_RS10790	COG1215	transferase activity, transferring glycosyl groups
ANAEK_RS10830	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
ANAEK_RS10850	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
ANAEK_RS10855	COG0189	ligase activity
ANAEK_RS10870	COG0009	L-threonylcarbamoyladenylate synthase
ANAEK_RS10875	COG4974	Belongs to the 'phage' integrase family
ANAEK_RS10880	COG1994	Peptidase M50
ANAEK_RS10885	COG0180	Tryptophanyl-tRNA synthetase
ANAEK_RS10890	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ANAEK_RS10895	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ANAEK_RS10900	COG1187	pseudouridine synthase activity
ANAEK_RS10930	COG0430	RNA-3'-phosphate cyclase activity
ANAEK_RS10935	COG0598	Magnesium transport protein CorA
ANAEK_RS10945	COG0489	protein tyrosine kinase activity
ANAEK_RS10975	COG2205	protein histidine kinase activity
ANAEK_RS10980	COG1250	3-hydroxyacyl-CoA dehydrogenase
ANAEK_RS10985	COG1024	Enoyl-CoA hydratase
ANAEK_RS10990	COG1960	acyl-CoA dehydrogenase activity
ANAEK_RS10995	COG1960	acyl-CoA dehydrogenase activity
ANAEK_RS11000	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ANAEK_RS11000	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ANAEK_RS11025	COG3005	denitrification pathway
ANAEK_RS11035	COG0494	nUDIX hydrolase
ANAEK_RS11050	COG1160	GTP binding
ANAEK_RS11055	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ANAEK_RS11070	COG0571	ribonuclease III activity
ANAEK_RS11075	COG1703	isobutyryl-CoA mutase activity
ANAEK_RS11085	COG1960	acyl-CoA dehydrogenase activity
ANAEK_RS11090	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ANAEK_RS11095	COG1024	Enoyl-CoA hydratase
ANAEK_RS11130	COG1494	fructose-1,6-bisphosphatase
ANAEK_RS11175	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ANAEK_RS11180	COG1253	flavin adenine dinucleotide binding
ANAEK_RS11190	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ANAEK_RS11200	COG0039	L-malate dehydrogenase activity
ANAEK_RS11205	COG0538	isocitrate dehydrogenase activity
ANAEK_RS11215	COG4191	Histidine kinase
ANAEK_RS11230	COG0505	Belongs to the CarA family
ANAEK_RS11245	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ANAEK_RS11255	COG0681	Belongs to the peptidase S26 family
ANAEK_RS11265	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ANAEK_RS11280	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ANAEK_RS11300	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ANAEK_RS11305	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
ANAEK_RS11310	COG5002	protein histidine kinase activity
ANAEK_RS11355	COG0745	RESPONSE REGULATOR receiver
ANAEK_RS11430	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ANAEK_RS11455	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ANAEK_RS11465	COG0189	ligase activity
ANAEK_RS11470	COG0443	Heat shock 70 kDa protein
ANAEK_RS11480	COG2921	Belongs to the UPF0250 family
ANAEK_RS11485	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ANAEK_RS11510	COG1309	transcriptional regulator
ANAEK_RS11535	COG1730	sister chromatid segregation
ANAEK_RS11610	COG2204	response regulator
ANAEK_RS11615	COG4191	Histidine kinase
ANAEK_RS11620	COG2843	Capsule synthesis protein
ANAEK_RS11645	COG0443	Heat shock 70 kDa protein
ANAEK_RS11655	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ANAEK_RS11670	COG0101	tRNA pseudouridine synthase activity
ANAEK_RS11685	COG0529	Catalyzes the synthesis of activated sulfate
ANAEK_RS11690	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ANAEK_RS11700	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ANAEK_RS11710	COG0443	Heat shock 70 kDa protein
ANAEK_RS11735	COG0149	triose-phosphate isomerase activity
ANAEK_RS11745	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ANAEK_RS11755	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
ANAEK_RS11790	COG0616	signal peptide processing
ANAEK_RS11795	COG0539	negative regulation of cytoplasmic translation
ANAEK_RS11795	COG2183	response to ionizing radiation
ANAEK_RS11815	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ANAEK_RS11825	COG0825	malonyl-CoA metabolic process
ANAEK_RS11855	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ANAEK_RS11880	COG0802	atpase or kinase
ANAEK_RS11885	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ANAEK_RS11885	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ANAEK_RS11895	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ANAEK_RS11900	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ANAEK_RS11910	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
ANAEK_RS11915	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ANAEK_RS11920	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ANAEK_RS11925	COG0590	tRNA wobble adenosine to inosine editing
ANAEK_RS11925	COG0037	tRNA processing
ANAEK_RS11940	COG0004	ammonium transporteR
ANAEK_RS11955	COG0776	regulation of translation
ANAEK_RS11960	COG3246	L-lysine catabolic process to acetate
ANAEK_RS11965	COG1607	acyl-coa hydrolase
ANAEK_RS11970	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ANAEK_RS11980	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ANAEK_RS11985	COG0482	sulfurtransferase activity
ANAEK_RS11990	COG2205	protein histidine kinase activity
ANAEK_RS11995	COG0617	tRNA 3'-terminal CCA addition
ANAEK_RS12010	COG2204	response regulator
ANAEK_RS12035	COG5002	protein histidine kinase activity
ANAEK_RS12040	COG2205	protein histidine kinase activity
ANAEK_RS12045	COG0024	Methionine aminopeptidase
ANAEK_RS12070	COG0840	transmembrane signaling receptor activity
ANAEK_RS12095	COG2353	YceI-like domain
ANAEK_RS12100	COG0259	pyridoxamine-phosphate oxidase activity
ANAEK_RS12120	COG4191	Histidine kinase
ANAEK_RS12125	COG2204	response regulator
ANAEK_RS12130	COG0589	response to stress
ANAEK_RS12155	COG3387	PFAM Glycoside hydrolase 15-related
ANAEK_RS12160	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
ANAEK_RS12165	COG0363	glucosamine-6-phosphate deaminase activity
ANAEK_RS12170	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ANAEK_RS12175	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
ANAEK_RS12180	COG1022	Amp-dependent synthetase and ligase
ANAEK_RS12185	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ANAEK_RS12205	COG2515	1-aminocyclopropane-1-carboxylate deaminase
ANAEK_RS12225	COG0343	queuine tRNA-ribosyltransferase activity
ANAEK_RS12230	COG0429	hydrolase of the alpha beta-hydrolase fold
ANAEK_RS12250	COG0437	4 iron, 4 sulfur cluster binding
ANAEK_RS12260	COG0038	chloride channel
ANAEK_RS12310	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
ANAEK_RS12315	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ANAEK_RS12320	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ANAEK_RS12345	COG3604	Transcriptional regulator
ANAEK_RS12350	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ANAEK_RS12355	COG2204	response regulator
ANAEK_RS12375	COG1677	Flagellar hook-basal body complex protein FliE
ANAEK_RS12385	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ANAEK_RS12425	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ANAEK_RS12430	COG1360	Flagellar Motor Protein
ANAEK_RS12435	COG2201	protein-glutamate methylesterase activity
ANAEK_RS12440	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ANAEK_RS12445	COG0835	chemotaxis
ANAEK_RS12450	COG0840	transmembrane signaling receptor activity
ANAEK_RS12455	COG2198	Histidine kinase
ANAEK_RS12455	COG0643	Histidine kinase
ANAEK_RS12460	COG0745	RESPONSE REGULATOR receiver
ANAEK_RS12475	COG0835	chemotaxis
ANAEK_RS12480	COG0840	transmembrane signaling receptor activity
ANAEK_RS12485	COG2201	protein-glutamate methylesterase activity
ANAEK_RS12490	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ANAEK_RS12515	COG1639	'signal transduction protein
ANAEK_RS12540	COG1338	Plays a role in the flagellum-specific transport system
ANAEK_RS12545	COG1987	bacterial-type flagellum assembly
ANAEK_RS12550	COG1684	flagellar biosynthetic protein fliR
ANAEK_RS12555	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ANAEK_RS12560	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ANAEK_RS12590	COG4786	Flagellar basal body rod
ANAEK_RS12615	COG0739	heme binding
ANAEK_RS12640	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ANAEK_RS12645	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ANAEK_RS12660	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ANAEK_RS12670	COG0457	Tetratricopeptide repeat
ANAEK_RS12670	COG0463	Glycosyl transferase, family 2
ANAEK_RS12685	COG1763	Mo-molybdopterin cofactor biosynthetic process
ANAEK_RS12690	COG0303	'Molybdopterin
ANAEK_RS12700	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ANAEK_RS12710	COG2239	Acts as a magnesium transporter
ANAEK_RS12715	COG2205	protein histidine kinase activity
ANAEK_RS12720	COG0745	RESPONSE REGULATOR receiver
ANAEK_RS12720	COG4566	intracellular signal transduction
ANAEK_RS12725	COG4191	Histidine kinase
ANAEK_RS12730	COG2204	response regulator
ANAEK_RS12775	COG1335	isochorismatase
ANAEK_RS12780	COG3481	metal-dependent phosphohydrolase, HD sub domain
ANAEK_RS12790	COG0084	hydrolase, TatD family'
ANAEK_RS12795	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ANAEK_RS12795	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ANAEK_RS12810	COG3599	regulation of cell shape
ANAEK_RS12875	COG0602	queuosine metabolic process
ANAEK_RS12880	COG0741	lytic transglycosylase activity
ANAEK_RS12920	COG2937	Belongs to the GPAT DAPAT family
ANAEK_RS12930	COG0483	inositol monophosphate 1-phosphatase activity
ANAEK_RS12940	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ANAEK_RS12945	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ANAEK_RS12965	COG1045	serine acetyltransferase
ANAEK_RS12980	COG3258	Cytochrome c
ANAEK_RS12995	COG0556	nucleotide-excision repair
ANAEK_RS13005	COG1278	Cold shock
ANAEK_RS13020	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ANAEK_RS13020	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ANAEK_RS13030	COG0658	competence protein
ANAEK_RS13030	COG2333	competence protein COMEC
ANAEK_RS13070	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ANAEK_RS13080	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ANAEK_RS13095	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ANAEK_RS13100	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ANAEK_RS13110	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ANAEK_RS13125	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ANAEK_RS13140	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ANAEK_RS13155	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ANAEK_RS13165	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ANAEK_RS13180	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ANAEK_RS13200	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ANAEK_RS13210	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ANAEK_RS13215	COG1278	Cold shock
ANAEK_RS13235	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ANAEK_RS13240	COG2766	serine protein kinase
ANAEK_RS13245	COG2718	Belongs to the UPF0229 family
ANAEK_RS13250	COG2719	SpoVR family
ANAEK_RS13270	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ANAEK_RS13295	COG1047	Peptidyl-prolyl cis-trans
ANAEK_RS13305	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ANAEK_RS13315	COG3411	Ferredoxin
ANAEK_RS13340	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
ANAEK_RS13370	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ANAEK_RS13385	COG5002	protein histidine kinase activity
ANAEK_RS13430	COG1269	ATP hydrolysis coupled proton transport
ANAEK_RS13460	COG2201	protein-glutamate methylesterase activity
ANAEK_RS13465	COG2205	protein histidine kinase activity
ANAEK_RS13475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ANAEK_RS13495	COG1309	transcriptional regulator
ANAEK_RS13515	COG1573	uracil-dna glycosylase
ANAEK_RS13520	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ANAEK_RS13550	COG0194	GDP metabolic process
ANAEK_RS13555	COG1561	YicC-like family, N-terminal region
ANAEK_RS13565	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ANAEK_RS13565	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ANAEK_RS13570	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ANAEK_RS13570	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ANAEK_RS13575	COG1560	Kdo2-lipid A biosynthetic process
ANAEK_RS13585	COG0859	PFAM glycosyl transferase family 9
ANAEK_RS13590	COG1519	Transferase
ANAEK_RS13600	COG1132	(ABC) transporter
ANAEK_RS13605	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ANAEK_RS13610	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ANAEK_RS13625	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ANAEK_RS13630	COG2095	MarC family integral membrane protein
ANAEK_RS13635	COG1216	Glycosyl transferase, family 2
ANAEK_RS13670	COG0437	4 iron, 4 sulfur cluster binding
ANAEK_RS13675	COG0243	molybdopterin cofactor binding
ANAEK_RS13685	COG5002	protein histidine kinase activity
ANAEK_RS13690	COG0745	RESPONSE REGULATOR receiver
ANAEK_RS13700	COG1053	succinate dehydrogenase
ANAEK_RS13710	COG0438	transferase activity, transferring glycosyl groups
ANAEK_RS13745	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ANAEK_RS13750	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ANAEK_RS13760	COG0489	protein tyrosine kinase activity
ANAEK_RS13785	COG2204	response regulator
ANAEK_RS13805	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ANAEK_RS13820	COG0577	efflux transmembrane transporter activity
ANAEK_RS13820	COG1136	(ABC) transporter
ANAEK_RS13880	COG0492	ferredoxin-NADP+ reductase activity
ANAEK_RS13900	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
ANAEK_RS13920	COG2169	Transcriptional regulator
ANAEK_RS13940	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ANAEK_RS13980	COG0237	dephospho-CoA kinase activity
ANAEK_RS14005	COG0443	Heat shock 70 kDa protein
ANAEK_RS14020	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ANAEK_RS14025	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ANAEK_RS14055	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ANAEK_RS14065	COG1652	LysM domain
ANAEK_RS14080	COG2203	Gaf domain
ANAEK_RS14080	COG3706	GGDEF domain
ANAEK_RS14080	COG5001	Diguanylate cyclase
ANAEK_RS14080	COG4251	negative regulation of phosphorylation
ANAEK_RS14085	COG0745	RESPONSE REGULATOR receiver
ANAEK_RS14085	COG1196	nuclear chromosome segregation
ANAEK_RS14095	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ANAEK_RS14110	COG0438	transferase activity, transferring glycosyl groups
ANAEK_RS14125	COG4932	domain protein
ANAEK_RS14125	COG5492	domain, Protein
ANAEK_RS14140	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ANAEK_RS14145	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ANAEK_RS14155	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ANAEK_RS14160	COG1480	7TM receptor with intracellular HD hydrolase
ANAEK_RS14170	COG0457	Tetratricopeptide repeat
ANAEK_RS14180	COG3956	TIGRFAM MazG family protein
ANAEK_RS14195	COG0495	leucyl-tRNA aminoacylation
ANAEK_RS14200	COG0017	Asparaginyl-tRNA synthetase
ANAEK_RS14205	COG0745	RESPONSE REGULATOR receiver
ANAEK_RS14210	COG2201	protein-glutamate methylesterase activity
ANAEK_RS14215	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ANAEK_RS14225	COG0835	chemotaxis
ANAEK_RS14235	COG3267	Type II secretory pathway component ExeA
ANAEK_RS14235	COG3409	Peptidoglycan-binding domain 1 protein
ANAEK_RS14240	COG2198	Histidine kinase
ANAEK_RS14240	COG0643	Histidine kinase
ANAEK_RS14260	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ANAEK_RS14260	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ANAEK_RS14270	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ANAEK_RS14270	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ANAEK_RS14285	COG0698	ribose 5-phosphate isomerase
ANAEK_RS14295	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ANAEK_RS14305	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ANAEK_RS14310	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ANAEK_RS14320	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ANAEK_RS14360	COG2827	Endonuclease containing a URI domain
ANAEK_RS14390	COG0438	transferase activity, transferring glycosyl groups
ANAEK_RS14395	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ANAEK_RS14410	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
ANAEK_RS14425	COG0367	asparagine synthase
ANAEK_RS14430	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ANAEK_RS14435	COG0318	PFAM AMP-dependent synthetase and ligase
ANAEK_RS14500	COG0438	transferase activity, transferring glycosyl groups
ANAEK_RS14505	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ANAEK_RS14520	COG0438	transferase activity, transferring glycosyl groups
ANAEK_RS14525	COG0493	'glutamate synthase
ANAEK_RS14525	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ANAEK_RS14555	COG2815	serine threonine protein kinase
ANAEK_RS14555	COG0515	serine threonine protein kinase
ANAEK_RS14575	COG3186	Phenylalanine-4-hydroxylase
ANAEK_RS14580	COG0488	(ABC) transporter
ANAEK_RS14590	COG0745	RESPONSE REGULATOR receiver
ANAEK_RS14600	COG0784	Response regulator, receiver
ANAEK_RS14600	COG2205	protein histidine kinase activity
ANAEK_RS14600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ANAEK_RS14600	COG2198	Histidine kinase
ANAEK_RS14630	COG1028	Short-chain dehydrogenase reductase Sdr
ANAEK_RS14670	COG2894	cell division
ANAEK_RS14675	COG4964	Belongs to the GSP D family
ANAEK_RS14760	COG0604	alcohol dehydrogenase
ANAEK_RS14790	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ANAEK_RS14800	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ANAEK_RS14815	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ANAEK_RS14840	COG1301	dicarboxylic acid transport
ANAEK_RS14855	COG0247	lactate metabolic process
ANAEK_RS14860	COG0277	FAD linked oxidase domain protein
ANAEK_RS14865	COG0277	FAD linked oxidase domain protein
ANAEK_RS14930	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ANAEK_RS14950	COG2226	methyltransferase
ANAEK_RS14980	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ANAEK_RS14995	COG0406	alpha-ribazole phosphatase activity
ANAEK_RS15010	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ANAEK_RS15015	COG0702	epimerase
ANAEK_RS15030	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
ANAEK_RS15040	COG0318	PFAM AMP-dependent synthetase and ligase
ANAEK_RS15045	COG0671	phosphoesterase, PA-phosphatase related
ANAEK_RS15080	COG1376	ErfK ybiS ycfS ynhG family protein
ANAEK_RS15080	COG1388	LysM domain
ANAEK_RS15100	COG2205	protein histidine kinase activity
ANAEK_RS15140	COG1215	transferase activity, transferring glycosyl groups
ANAEK_RS15145	COG1649	PFAM Uncharacterised BCR, COG1649
ANAEK_RS15145	COG0726	polysaccharide deacetylase
ANAEK_RS15155	COG4968	Prepilin-type N-terminal cleavage methylation domain
ANAEK_RS15185	COG1053	succinate dehydrogenase
ANAEK_RS15205	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ANAEK_RS15205	COG1404	Belongs to the peptidase S8 family
ANAEK_RS15215	COG2267	carboxylic ester hydrolase activity
ANAEK_RS15235	COG2205	protein histidine kinase activity
ANAEK_RS15235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ANAEK_RS15240	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
ANAEK_RS15295	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ANAEK_RS15300	COG0513	Belongs to the DEAD box helicase family
ANAEK_RS15305	COG2205	protein histidine kinase activity
ANAEK_RS15305	COG2202	Pas domain
ANAEK_RS15315	COG2271	Major facilitator Superfamily
ANAEK_RS15325	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ANAEK_RS15340	COG0484	heat shock protein binding
ANAEK_RS15375	COG1136	(ABC) transporter
ANAEK_RS15375	COG0577	efflux transmembrane transporter activity
ANAEK_RS15380	COG1136	(ABC) transporter
ANAEK_RS15380	COG4591	ABC-type transport system involved in lipoprotein release permease component
ANAEK_RS15385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ANAEK_RS15390	COG3275	phosphorelay sensor kinase activity
ANAEK_RS15395	COG3279	Response regulator of the LytR AlgR family
ANAEK_RS15405	COG1620	l-lactate permease
ANAEK_RS15415	COG1139	Iron-sulfur cluster binding protein
ANAEK_RS15430	COG2226	methyltransferase
ANAEK_RS15490	COG2264	protein methyltransferase activity
ANAEK_RS15520	COG2860	membrane
ANAEK_RS15550	COG4106	trans-aconitate 2-methyltransferase activity
ANAEK_RS15555	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ANAEK_RS15560	COG0745	RESPONSE REGULATOR receiver
ANAEK_RS15570	COG3800	Transcriptional regulator
ANAEK_RS15570	COG1396	sequence-specific DNA binding
ANAEK_RS15580	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ANAEK_RS15600	COG0366	Alpha amylase catalytic
ANAEK_RS15635	COG0318	PFAM AMP-dependent synthetase and ligase
ANAEK_RS15650	COG1013	pyruvate-flavodoxin oxidoreductase activity
ANAEK_RS15655	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ANAEK_RS15655	COG0674	pyruvate-flavodoxin oxidoreductase activity
ANAEK_RS15665	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
ANAEK_RS15680	COG2703	oxygen carrier activity
ANAEK_RS15685	COG0277	FAD linked oxidase domain protein
ANAEK_RS15690	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ANAEK_RS15705	COG1960	acyl-CoA dehydrogenase activity
ANAEK_RS15720	COG0702	epimerase
ANAEK_RS15730	COG3272	Protein of unknown function (DUF1722)
ANAEK_RS15740	COG1295	ribonuclease BN
ANAEK_RS15745	COG0443	Heat shock 70 kDa protein
ANAEK_RS15750	COG0443	Heat shock 70 kDa protein
ANAEK_RS15765	COG0667	Aldo Keto reductase
ANAEK_RS15770	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ANAEK_RS15785	COG0667	Aldo Keto reductase
ANAEK_RS15790	COG0693	protein deglycase activity
ANAEK_RS15805	COG0513	Belongs to the DEAD box helicase family
ANAEK_RS15830	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ANAEK_RS15835	COG1216	Glycosyl transferase, family 2
ANAEK_RS15840	COG1216	Glycosyl transferase, family 2
ANAEK_RS15880	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ANAEK_RS15895	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ANAEK_RS16005	COG0436	Aminotransferase
ANAEK_RS16010	COG0840	transmembrane signaling receptor activity
ANAEK_RS16015	COG0137	argininosuccinate synthase activity
ANAEK_RS16050	COG2204	response regulator
ANAEK_RS16070	COG0702	epimerase
ANAEK_RS16095	COG2267	carboxylic ester hydrolase activity
ANAEK_RS16105	COG0535	radical SAM domain protein
ANAEK_RS16115	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
ANAEK_RS16120	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
ANAEK_RS16125	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
ANAEK_RS16165	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ANAEK_RS16165	COG3608	succinylglutamate desuccinylase aspartoacylase
ANAEK_RS16180	COG0339	signal peptide processing
ANAEK_RS16185	COG3852	Histidine kinase
ANAEK_RS16195	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ANAEK_RS16200	COG1131	(ABC) transporter
ANAEK_RS16205	COG1131	(ABC) transporter
ANAEK_RS16210	COG0842	Transport permease protein
ANAEK_RS16215	COG0842	Transport permease protein
ANAEK_RS16220	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
ANAEK_RS16225	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ANAEK_RS16225	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ANAEK_RS16240	COG1175	transmembrane transport
ANAEK_RS16245	COG0395	ABC-type sugar transport system, permease component
ANAEK_RS16275	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ANAEK_RS16280	COG1595	DNA-templated transcription, initiation
ANAEK_RS16295	COG1162	GTPase activity
ANAEK_RS16300	COG0784	Response regulator, receiver
ANAEK_RS16300	COG2205	protein histidine kinase activity
ANAEK_RS16315	COG1309	transcriptional regulator
ANAEK_RS16320	COG1028	Short-chain dehydrogenase reductase Sdr
ANAEK_RS16345	COG4191	Histidine kinase
ANAEK_RS16355	COG0626	cystathionine gamma-synthase activity
ANAEK_RS16360	COG1136	(ABC) transporter
ANAEK_RS16390	COG0723	plastoquinol--plastocyanin reductase activity
ANAEK_RS16420	COG2855	membrane
ANAEK_RS16435	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ANAEK_RS16520	COG1064	alcohol dehydrogenase
ANAEK_RS16535	COG1131	(ABC) transporter
ANAEK_RS16540	COG0025	NhaP-type Na H and K H
ANAEK_RS16555	COG2860	membrane
ANAEK_RS16565	COG1278	Cold shock
ANAEK_RS16585	COG3459	Glycosyltransferase 36 associated
ANAEK_RS16595	COG1125	glycine betaine transport
ANAEK_RS16595	COG0517	IMP dehydrogenase activity
ANAEK_RS16600	COG1174	glycine betaine transport
ANAEK_RS16625	COG1404	Belongs to the peptidase S8 family
ANAEK_RS16635	COG2814	Major facilitator Superfamily
ANAEK_RS16640	COG2353	YceI-like domain
ANAEK_RS16665	COG2130	NADP-dependent
ANAEK_RS16675	COG3387	PFAM Glycoside hydrolase 15-related
ANAEK_RS16695	COG1993	acr, cog1993
ANAEK_RS16705	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ANAEK_RS16725	COG0646	methionine synthase
ANAEK_RS16725	COG1410	methionine synthase
ANAEK_RS16735	COG0583	DNA-binding transcription factor activity
ANAEK_RS16760	COG3436	PFAM IS66 Orf2 family protein
ANAEK_RS16855	COG1064	alcohol dehydrogenase
ANAEK_RS16870	COG1063	alcohol dehydrogenase
ANAEK_RS16880	COG0583	DNA-binding transcription factor activity
ANAEK_RS16890	COG3321	synthase
ANAEK_RS16890	COG0604	alcohol dehydrogenase
ANAEK_RS16900	COG1063	alcohol dehydrogenase
ANAEK_RS16915	COG0006	proline dipeptidase activity
ANAEK_RS16945	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ANAEK_RS16945	COG1918	ferrous iron import across plasma membrane
ANAEK_RS16950	COG0604	alcohol dehydrogenase
ANAEK_RS16975	COG0516	GMP reductase activity
ANAEK_RS16980	COG2132	Multicopper oxidase
ANAEK_RS16990	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ANAEK_RS17015	COG1704	LemA family
ANAEK_RS17020	COG0501	Belongs to the peptidase M48B family
ANAEK_RS17030	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ANAEK_RS17065	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ANAEK_RS17085	COG5337	Spore coat protein CotH
ANAEK_RS17160	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ANAEK_RS17195	COG2204	response regulator
ANAEK_RS17215	COG5000	phosphorelay sensor kinase activity
ANAEK_RS17230	COG2252	PERMEase
ANAEK_RS17235	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ANAEK_RS17245	COG2521	methyltransferase
ANAEK_RS17245	COG2136	Putative SAM-dependent methyltransferase
ANAEK_RS17265	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ANAEK_RS17265	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ANAEK_RS17280	COG0544	peptidyl-prolyl cis-trans isomerase activity
ANAEK_RS17295	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ANAEK_RS17305	COG0463	Glycosyl transferase, family 2
ANAEK_RS17340	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ANAEK_RS17355	COG0709	Synthesizes selenophosphate from selenide and ATP
ANAEK_RS17370	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ANAEK_RS17390	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ANAEK_RS17400	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ANAEK_RS17410	COG0210	DNA helicase
ANAEK_RS17440	COG0564	pseudouridine synthase activity
ANAEK_RS17445	COG0625	glutathione transferase activity
ANAEK_RS17450	COG0612	Peptidase, M16
ANAEK_RS17460	COG4191	Histidine kinase
ANAEK_RS17475	COG0739	heme binding
ANAEK_RS17480	COG0483	inositol monophosphate 1-phosphatase activity
ANAEK_RS17495	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ANAEK_RS17510	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ANAEK_RS17520	COG1619	proteins homologs of microcin C7 resistance protein MccF
ANAEK_RS17525	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ANAEK_RS17530	COG0628	permease
ANAEK_RS17535	COG0545	Peptidyl-prolyl cis-trans isomerase
ANAEK_RS17595	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ANAEK_RS17670	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ANAEK_RS17675	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ANAEK_RS17680	COG1846	Transcriptional regulator
ANAEK_RS17700	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ANAEK_RS17710	COG0471	metal ion transport
ANAEK_RS17710	COG3273	potassium ion transport
ANAEK_RS17730	COG0123	including yeast histone deacetylase and acetoin utilization protein
ANAEK_RS17740	COG3123	guanosine phosphorylase activity
ANAEK_RS17755	COG0587	DNA-directed DNA polymerase activity
ANAEK_RS17760	COG0730	response to heat
ANAEK_RS17770	COG2197	response regulator
ANAEK_RS17775	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ANAEK_RS17810	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ANAEK_RS17820	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ANAEK_RS17845	COG4206	TonB-dependent receptor
ANAEK_RS17855	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ANAEK_RS17860	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ANAEK_RS17865	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ANAEK_RS17880	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ANAEK_RS17885	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ANAEK_RS17900	COG3852	Histidine kinase
ANAEK_RS17920	COG2096	Adenosyltransferase
ANAEK_RS17930	COG0316	Belongs to the HesB IscA family
ANAEK_RS17935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ANAEK_RS17940	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ANAEK_RS17950	COG0746	molybdenum cofactor guanylyltransferase activity
ANAEK_RS17975	COG4106	trans-aconitate 2-methyltransferase activity
ANAEK_RS17985	COG1741	Belongs to the pirin family
ANAEK_RS18015	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ANAEK_RS18025	COG1937	Protein conserved in bacteria
ANAEK_RS18030	COG2217	Heavy metal translocating P-type atpase
ANAEK_RS18045	COG4941	Belongs to the sigma-70 factor family
ANAEK_RS18050	COG3795	YCII-related domain
ANAEK_RS18070	COG0438	transferase activity, transferring glycosyl groups
ANAEK_RS18080	COG0667	Aldo Keto reductase
ANAEK_RS18085	COG0583	DNA-binding transcription factor activity
ANAEK_RS18090	COG3118	belongs to the thioredoxin family
ANAEK_RS18100	COG1597	lipid kinase activity
ANAEK_RS18120	COG0840	transmembrane signaling receptor activity
ANAEK_RS18125	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ANAEK_RS18140	COG1136	(ABC) transporter
ANAEK_RS18140	COG0577	efflux transmembrane transporter activity
ANAEK_RS18145	COG1136	(ABC) transporter
ANAEK_RS18145	COG0577	efflux transmembrane transporter activity
ANAEK_RS18155	COG0745	RESPONSE REGULATOR receiver
ANAEK_RS18180	COG0330	HflC and HflK could
ANAEK_RS18200	COG1053	succinate dehydrogenase
ANAEK_RS18200	COG3976	FMN-binding domain protein
ANAEK_RS18205	COG0519	Catalyzes the synthesis of GMP from XMP
ANAEK_RS18205	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ANAEK_RS18210	COG2205	protein histidine kinase activity
ANAEK_RS18240	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
ANAEK_RS18265	COG1196	nuclear chromosome segregation
ANAEK_RS18265	COG0739	heme binding
ANAEK_RS18265	COG0741	lytic transglycosylase activity
ANAEK_RS18270	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ANAEK_RS18280	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ANAEK_RS18300	COG2267	carboxylic ester hydrolase activity
ANAEK_RS18330	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ANAEK_RS18335	COG1090	epimerase
ANAEK_RS18345	COG1214	PFAM Peptidase M22, glycoprotease
ANAEK_RS18350	COG0750	zinc metalloprotease
ANAEK_RS18360	COG4589	Belongs to the CDS family
ANAEK_RS18365	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ANAEK_RS18410	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ANAEK_RS18415	COG0459	protein refolding
ANAEK_RS18465	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ANAEK_RS18510	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ANAEK_RS18515	COG1183	phosphatidylcholine synthase activity
ANAEK_RS18520	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ANAEK_RS18565	COG1100	Small GTP-binding protein
ANAEK_RS18575	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ANAEK_RS18585	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ANAEK_RS18600	COG0590	tRNA wobble adenosine to inosine editing
ANAEK_RS18615	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ANAEK_RS18615	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ANAEK_RS18640	COG2261	transglycosylase associated protein
ANAEK_RS18680	COG0651	ATP synthesis coupled electron transport
ANAEK_RS18685	COG0651	ATP synthesis coupled electron transport
ANAEK_RS18700	COG0651	ATP synthesis coupled electron transport
ANAEK_RS18705	COG0649	NAD binding
ANAEK_RS18710	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ANAEK_RS18730	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ANAEK_RS18735	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ANAEK_RS18750	COG0475	glutathione-regulated potassium exporter activity
ANAEK_RS18765	COG0739	heme binding
ANAEK_RS18775	COG0539	negative regulation of cytoplasmic translation
ANAEK_RS18815	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ANAEK_RS18825	COG1428	Deoxynucleoside kinase
ANAEK_RS18855	COG0484	heat shock protein binding
ANAEK_RS18865	COG0631	protein serine/threonine phosphatase activity
ANAEK_RS18870	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ANAEK_RS18890	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ANAEK_RS18900	COG0477	Major facilitator Superfamily
ANAEK_RS18905	COG2815	serine threonine protein kinase
ANAEK_RS18905	COG0515	serine threonine protein kinase
ANAEK_RS18920	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ANAEK_RS18925	COG0840	transmembrane signaling receptor activity
ANAEK_RS18940	COG0626	cystathionine gamma-synthase activity
ANAEK_RS18955	COG0477	Major facilitator Superfamily
ANAEK_RS18985	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ANAEK_RS18995	COG0840	transmembrane signaling receptor activity
ANAEK_RS19000	COG1902	pentaerythritol trinitrate reductase activity
ANAEK_RS19010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ANAEK_RS19015	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ANAEK_RS19025	COG5002	protein histidine kinase activity
ANAEK_RS19025	COG3850	Histidine kinase
ANAEK_RS19030	COG4122	O-methyltransferase activity
ANAEK_RS19035	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
ANAEK_RS19045	COG3852	Histidine kinase
ANAEK_RS19050	COG2204	response regulator
ANAEK_RS19055	COG1271	oxidase subunit
ANAEK_RS19060	COG1294	oxidase, subunit
ANAEK_RS19070	COG2226	methyltransferase
ANAEK_RS19085	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ANAEK_RS19105	COG0515	serine threonine protein kinase
ANAEK_RS19115	COG1024	Enoyl-CoA hydratase
ANAEK_RS19120	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
ANAEK_RS19145	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
ANAEK_RS19155	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ANAEK_RS19170	COG0243	molybdopterin cofactor binding
ANAEK_RS19170	COG3383	formate dehydrogenase (NAD+) activity
ANAEK_RS19175	COG3383	formate dehydrogenase (NAD+) activity
ANAEK_RS19175	COG0243	molybdopterin cofactor binding
ANAEK_RS19180	COG0437	4 iron, 4 sulfur cluster binding
ANAEK_RS19185	COG2864	formate dehydrogenase
ANAEK_RS19235	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ANAEK_RS19240	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ANAEK_RS19250	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ANAEK_RS19295	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ANAEK_RS19320	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ANAEK_RS19335	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ANAEK_RS19345	COG0577	efflux transmembrane transporter activity
ANAEK_RS19345	COG1136	(ABC) transporter
ANAEK_RS19355	COG1705	Flagellar rod assembly protein muramidase FlgJ
ANAEK_RS19355	COG1388	LysM domain
ANAEK_RS19365	COG2204	response regulator
ANAEK_RS19390	COG0793	Belongs to the peptidase S41A family
ANAEK_RS19405	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ANAEK_RS19435	COG0673	inositol 2-dehydrogenase activity
ANAEK_RS19445	COG2027	D-alanyl-D-alanine carboxypeptidase
ANAEK_RS19470	COG0640	Transcriptional regulator
ANAEK_RS19565	COG2003	Belongs to the UPF0758 family
ANAEK_RS19575	COG2353	YceI-like domain
ANAEK_RS19585	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ANAEK_RS19595	COG0436	Aminotransferase
ANAEK_RS19620	COG1192	Involved in chromosome partitioning
ANAEK_RS19645	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ANAEK_RS19650	COG0047	phosphoribosylformylglycinamidine synthase activity
ANAEK_RS19670	COG0312	modulator of DNA gyrase
ANAEK_RS19675	COG0312	modulator of DNA gyrase
ANAEK_RS19690	COG4221	oxidoreductase activity
ANAEK_RS19720	COG2205	protein histidine kinase activity
ANAEK_RS19725	COG0745	RESPONSE REGULATOR receiver
ANAEK_RS19770	COG3436	PFAM IS66 Orf2 family protein
ANAEK_RS19780	COG1278	Cold shock
ANAEK_RS19860	COG2204	response regulator
ANAEK_RS19875	COG3852	Histidine kinase
ANAEK_RS19880	COG0270	DNA (cytosine-5-)-methyltransferase activity
ANAEK_RS19930	COG3436	PFAM IS66 Orf2 family protein
ANAEK_RS20010	COG1595	DNA-templated transcription, initiation
ANAEK_RS20015	COG1201	RNA secondary structure unwinding
ANAEK_RS20025	COG1074	ATP-dependent DNA helicase activity
ANAEK_RS20035	COG0653	protein targeting
ANAEK_RS20065	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ANAEK_RS20070	COG0745	RESPONSE REGULATOR receiver
ANAEK_RS20085	COG0840	transmembrane signaling receptor activity
ANAEK_RS20095	COG1028	Short-chain dehydrogenase reductase Sdr
ANAEK_RS20095	COG0604	alcohol dehydrogenase
ANAEK_RS20095	COG3321	synthase
ANAEK_RS20100	COG3321	synthase
ANAEK_RS20100	COG0604	alcohol dehydrogenase
ANAEK_RS20110	COG2378	regulation of single-species biofilm formation
ANAEK_RS20140	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ANAEK_RS20180	COG0640	Transcriptional regulator
ANAEK_RS20185	COG0798	PFAM Bile acid sodium symporter
ANAEK_RS20190	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ANAEK_RS20215	COG0488	(ABC) transporter
ANAEK_RS20275	COG0154	amidase activity
ANAEK_RS20285	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ANAEK_RS20290	COG0280	phosphate acetyltransferase
ANAEK_RS20290	COG0281	malic enzyme
ANAEK_RS20330	COG1136	(ABC) transporter
ANAEK_RS20340	COG2840	Smr protein MutS2
ANAEK_RS20355	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ANAEK_RS20360	COG2239	Acts as a magnesium transporter
ANAEK_RS20385	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ANAEK_RS20390	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ANAEK_RS20390	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ANAEK_RS20395	COG0492	ferredoxin-NADP+ reductase activity
ANAEK_RS20425	COG0405	Gamma-glutamyltransferase
ANAEK_RS20435	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ANAEK_RS20440	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ANAEK_RS20485	COG2379	hydroxypyruvate reductase
ANAEK_RS20500	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ANAEK_RS20505	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ANAEK_RS20550	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ANAEK_RS20550	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ANAEK_RS20555	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ANAEK_RS20565	COG0670	Belongs to the BI1 family
ANAEK_RS20575	COG0584	glycerophosphoryl diester phosphodiesterase
ANAEK_RS20590	COG0488	(ABC) transporter
ANAEK_RS20595	COG2814	Major facilitator Superfamily
ANAEK_RS20665	COG3647	Membrane
ANAEK_RS20680	COG0704	Plays a role in the regulation of phosphate uptake
ANAEK_RS20685	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ANAEK_RS20690	COG0581	inorganic phosphate transmembrane transporter activity
ANAEK_RS20695	COG0573	inorganic phosphate transmembrane transporter activity
ANAEK_RS20700	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ANAEK_RS20710	COG5002	protein histidine kinase activity
ANAEK_RS20730	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ANAEK_RS20730	COG0116	Belongs to the methyltransferase superfamily
ANAEK_RS20775	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ANAEK_RS20780	COG2363	Small membrane protein
ANAEK_RS20785	COG2154	pterin-4-alpha-carbinolamine dehydratase
ANAEK_RS20795	COG1408	metallophosphoesterase
ANAEK_RS20835	COG0811	peptide transport
ANAEK_RS20855	COG2030	dehydratase
ANAEK_RS20865	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ANAEK_RS20880	COG0768	penicillin binding
ANAEK_RS20885	COG0574	Belongs to the PEP-utilizing enzyme family
ANAEK_RS20885	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ANAEK_RS20890	COG0301	tRNA thio-modification
ANAEK_RS20895	COG0425	Belongs to the sulfur carrier protein TusA family
ANAEK_RS20910	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ANAEK_RS20910	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ANAEK_RS20925	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ANAEK_RS20930	COG0512	Glutamine amidotransferase of anthranilate synthase
ANAEK_RS20940	COG0134	indole-3-glycerol-phosphate synthase activity
ANAEK_RS20945	COG0135	phosphoribosylanthranilate isomerase activity
ANAEK_RS20950	COG0133	tryptophan synthase activity
ANAEK_RS20955	COG0159	tryptophan synthase activity
ANAEK_RS20965	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
ANAEK_RS21005	COG1846	Transcriptional regulator
ANAEK_RS21010	COG0697	spore germination
ANAEK_RS21020	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ANAEK_RS21020	COG0517	IMP dehydrogenase activity
ANAEK_RS21025	COG0235	Class ii aldolase
ANAEK_RS21030	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ANAEK_RS21035	COG0179	Fumarylacetoacetate (FAA) hydrolase
ANAEK_RS21050	COG0019	diaminopimelate decarboxylase activity
ANAEK_RS21075	COG0346	lactoylglutathione lyase activity
ANAEK_RS21085	COG2715	membrane protein required for spore maturation
ANAEK_RS21090	COG0700	Nucleoside recognition
ANAEK_RS21135	COG0297	glycogen (starch) synthase activity
ANAEK_RS21185	COG0438	transferase activity, transferring glycosyl groups
ANAEK_RS21195	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ANAEK_RS21205	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ANAEK_RS21225	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ANAEK_RS21235	COG1028	Short-chain dehydrogenase reductase Sdr
ANAEK_RS21245	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ANAEK_RS21275	COG2076	Multidrug Resistance protein
ANAEK_RS21315	COG2205	protein histidine kinase activity
ANAEK_RS21315	COG0784	Response regulator, receiver
ANAEK_RS21315	COG2198	Histidine kinase
ANAEK_RS21330	COG1960	acyl-CoA dehydrogenase activity
ANAEK_RS21345	COG2205	protein histidine kinase activity
ANAEK_RS21345	COG0784	Response regulator, receiver
ANAEK_RS21345	COG2198	Histidine kinase
ANAEK_RS21350	COG0784	Response regulator, receiver
ANAEK_RS21350	COG2198	Histidine kinase
ANAEK_RS21350	COG5002	protein histidine kinase activity
ANAEK_RS21400	COG4580	involved in the transport of maltose and maltodextrins
ANAEK_RS21410	COG0395	ABC-type sugar transport system, permease component
ANAEK_RS21415	COG1175	transmembrane transport
ANAEK_RS21430	COG0366	Alpha amylase catalytic
ANAEK_RS21475	COG0438	transferase activity, transferring glycosyl groups
ANAEK_RS21480	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ANAEK_RS21510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ANAEK_RS21515	COG0577	efflux transmembrane transporter activity
ANAEK_RS21515	COG1136	(ABC) transporter
ANAEK_RS21520	COG0577	efflux transmembrane transporter activity
ANAEK_RS21520	COG1136	(ABC) transporter
ANAEK_RS21525	COG0577	efflux transmembrane transporter activity
ANAEK_RS21525	COG1136	(ABC) transporter
ANAEK_RS21530	COG0681	Belongs to the peptidase S26 family
ANAEK_RS21545	COG3259	Nickel-dependent hydrogenase
ANAEK_RS21565	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANAEK_RS21595	COG1560	Kdo2-lipid A biosynthetic process
ANAEK_RS21600	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ANAEK_RS21605	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ANAEK_RS21625	COG0564	pseudouridine synthase activity
ANAEK_RS21635	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ANAEK_RS21660	COG3339	Conserved Protein
ANAEK_RS21700	COG0457	Tetratricopeptide repeat
ANAEK_RS21705	COG1674	ftsk spoiiie
ANAEK_RS21735	COG0839	Belongs to the complex I subunit 6 family
ANAEK_RS21775	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ANAEK_RS21845	COG1193	negative regulation of DNA recombination
ANAEK_RS21850	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ANAEK_RS21880	COG5002	protein histidine kinase activity
ANAEK_RS21890	COG0306	phosphate transporter
ANAEK_RS21895	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ANAEK_RS21960	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ANAEK_RS21980	COG3852	Histidine kinase
ANAEK_RS21995	COG3852	Histidine kinase
ANAEK_RS22000	COG2204	response regulator
ANAEK_RS22010	COG0174	glutamine synthetase
ANAEK_RS22045	COG0411	ABC transporter
ANAEK_RS22055	COG0559	Belongs to the binding-protein-dependent transport system permease family
ANAEK_RS22065	COG0745	RESPONSE REGULATOR receiver
ANAEK_RS22080	COG1472	Belongs to the glycosyl hydrolase 3 family
ANAEK_RS22095	COG0714	Associated with various cellular activities
ANAEK_RS22125	COG3206	protein involved in exopolysaccharide biosynthesis
ANAEK_RS22125	COG0489	protein tyrosine kinase activity
ANAEK_RS22150	COG0438	transferase activity, transferring glycosyl groups
ANAEK_RS22160	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ANAEK_RS22190	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ANAEK_RS22195	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
ANAEK_RS22235	COG0463	Glycosyl transferase, family 2
ANAEK_RS22260	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ANAEK_RS22285	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ANAEK_RS22290	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
ANAEK_RS22315	COG3852	Histidine kinase
ANAEK_RS22320	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
ANAEK_RS22325	COG1691	(AIR) carboxylase
ANAEK_RS22335	COG2198	Histidine kinase
ANAEK_RS22335	COG0643	Histidine kinase
ANAEK_RS22340	COG2201	protein-glutamate methylesterase activity
ANAEK_RS22350	COG0840	transmembrane signaling receptor activity
ANAEK_RS22350	COG3290	protein histidine kinase activity
ANAEK_RS22355	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ANAEK_RS22360	COG2205	protein histidine kinase activity
ANAEK_RS22360	COG2202	Pas domain
ANAEK_RS22365	COG1100	Small GTP-binding protein
ANAEK_RS22370	COG1199	ATP-dependent helicase activity
ANAEK_RS22390	COG0484	heat shock protein binding
ANAEK_RS22395	COG0443	Heat shock 70 kDa protein
ANAEK_RS22425	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ANAEK_RS22430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ANAEK_RS22435	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ANAEK_RS22440	COG0012	GTP binding
ANAEK_RS22450	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ANAEK_RS22495	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ANAEK_RS22515	COG0071	Belongs to the small heat shock protein (HSP20) family
ANAEK_RS22525	COG1475	DNA binding
ANAEK_RS22530	COG1192	Involved in chromosome partitioning
ANAEK_RS22560	COG0594	ribonuclease P activity
ANAEK_RS22600	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ANAEK_RS22660	COG0456	acetyltransferase
ANAEK_RS22670	COG0840	transmembrane signaling receptor activity
ANAEK_RS22675	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism