locus-tag	class	description
ANCC_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ANCC_RS00010	COG0592	DNA-directed DNA polymerase activity
ANCC_RS00025	COG0187	DNA topoisomerase II activity
ANCC_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ANCC_RS00060	COG1070	Carbohydrate kinase
ANCC_RS00115	COG0534	Mate efflux family protein
ANCC_RS00120	COG1748	Saccharopine dehydrogenase
ANCC_RS00135	COG3711	transcriptional antiterminator
ANCC_RS00150	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANCC_RS00160	COG1609	Transcriptional regulator
ANCC_RS00190	COG2390	Transcriptional regulator
ANCC_RS00200	COG0017	Asparaginyl-tRNA synthetase
ANCC_RS00210	COG1610	YqeY-like protein
ANCC_RS00220	COG0069	glutamate synthase activity
ANCC_RS00225	COG0084	hydrolase, TatD family'
ANCC_RS00230	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ANCC_RS00240	COG0590	tRNA wobble adenosine to inosine editing
ANCC_RS00245	COG0598	Magnesium transport protein CorA
ANCC_RS00270	COG3775	system Galactitol-specific IIC component
ANCC_RS00280	COG1063	alcohol dehydrogenase
ANCC_RS00285	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ANCC_RS00290	COG1028	Short-chain dehydrogenase reductase Sdr
ANCC_RS00295	COG2357	RelA SpoT domain protein
ANCC_RS00315	COG5566	PFAM Mor transcription activator
ANCC_RS00325	COG4717	serine-type aminopeptidase activity
ANCC_RS00330	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ANCC_RS00335	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ANCC_RS00350	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ANCC_RS00355	COG2088	sporulation resulting in formation of a cellular spore
ANCC_RS00465	COG1982	Orn Lys Arg decarboxylase major
ANCC_RS00470	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ANCC_RS00475	COG0470	DNA polymerase III
ANCC_RS00480	COG1774	PSP1 C-terminal conserved region
ANCC_RS00485	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ANCC_RS00490	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ANCC_RS00495	COG2002	toxin-antitoxin pair type II binding
ANCC_RS00515	COG1846	Transcriptional regulator
ANCC_RS00520	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ANCC_RS00545	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ANCC_RS00555	COG3716	PTS system mannose fructose sorbose family IID component
ANCC_RS00565	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ANCC_RS00570	COG1028	Short-chain dehydrogenase reductase Sdr
ANCC_RS00580	COG1737	Transcriptional regulator
ANCC_RS00595	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ANCC_RS00600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ANCC_RS00605	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ANCC_RS00610	COG1120	ATPase activity
ANCC_RS00630	COG3732	PTS system glucitol sorbitol-specific
ANCC_RS00635	COG3730	PTS system glucitol sorbitol-specific
ANCC_RS00645	COG1063	alcohol dehydrogenase
ANCC_RS00655	COG2390	Transcriptional regulator
ANCC_RS00695	COG0657	acetylesterase activity
ANCC_RS00700	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ANCC_RS00700	COG1263	PTS System
ANCC_RS00700	COG2190	(PTS) system
ANCC_RS00705	COG3711	transcriptional antiterminator
ANCC_RS00710	COG1193	negative regulation of DNA recombination
ANCC_RS00715	COG3481	metal-dependent phosphohydrolase, HD sub domain
ANCC_RS00720	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ANCC_RS00765	COG1454	alcohol dehydrogenase
ANCC_RS00770	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ANCC_RS00780	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ANCC_RS00785	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ANCC_RS00790	COG0490	domain, Protein
ANCC_RS00790	COG0471	metal ion transport
ANCC_RS00795	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ANCC_RS00805	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ANCC_RS00860	COG1051	belongs to the nudix hydrolase family
ANCC_RS00870	COG0785	Cytochrome C biogenesis protein
ANCC_RS00875	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ANCC_RS00895	COG1454	alcohol dehydrogenase
ANCC_RS00915	COG3022	response to hydroperoxide
ANCC_RS00930	COG0531	amino acid
ANCC_RS00935	COG2423	ornithine cyclodeaminase activity
ANCC_RS00965	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ANCC_RS01045	COG3715	PTS system
ANCC_RS01050	COG3716	PTS system mannose fructose sorbose family IID component
ANCC_RS01055	COG0673	inositol 2-dehydrogenase activity
ANCC_RS01060	COG0363	glucosamine-6-phosphate deaminase activity
ANCC_RS01140	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ANCC_RS01155	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ANCC_RS01260	COG0270	DNA (cytosine-5-)-methyltransferase activity
ANCC_RS01395	COG2003	Belongs to the UPF0758 family
ANCC_RS01405	COG1895	HEPN domain
ANCC_RS01480	COG1475	DNA binding
ANCC_RS01485	COG4443	Transcriptional Coactivator p15 (PC4)
ANCC_RS01540	COG3800	Transcriptional regulator
ANCC_RS01540	COG1396	sequence-specific DNA binding
ANCC_RS01585	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ANCC_RS01605	COG3843	relaxase mobilization nuclease domain protein
ANCC_RS01725	COG1132	(ABC) transporter
ANCC_RS01730	COG1132	(ABC) transporter
ANCC_RS01730	COG2375	cellular response to nickel ion
ANCC_RS01750	COG1129	ABC transporter
ANCC_RS01765	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
ANCC_RS01775	COG1021	2,3-dihydroxybenzoate-AMP ligase
ANCC_RS01790	COG3433	isochorismatase activity
ANCC_RS01790	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ANCC_RS01790	COG2226	methyltransferase
ANCC_RS01810	COG1129	ABC transporter
ANCC_RS01820	COG1132	(ABC) transporter
ANCC_RS01825	COG0534	Mate efflux family protein
ANCC_RS01845	COG1131	(ABC) transporter
ANCC_RS01890	COG1518	maintenance of DNA repeat elements
ANCC_RS01895	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
ANCC_RS01915	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ANCC_RS01925	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ANCC_RS01930	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ANCC_RS01935	COG1116	anion transmembrane transporter activity
ANCC_RS01940	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANCC_RS01950	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ANCC_RS01970	COG3775	system Galactitol-specific IIC component
ANCC_RS01975	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ANCC_RS01985	COG1063	alcohol dehydrogenase
ANCC_RS02015	COG1063	alcohol dehydrogenase
ANCC_RS02020	COG3716	PTS system mannose fructose sorbose family IID component
ANCC_RS02030	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ANCC_RS02035	COG1028	Short-chain dehydrogenase reductase Sdr
ANCC_RS02040	COG2188	Transcriptional regulator
ANCC_RS02055	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
ANCC_RS02060	COG2084	Dehydrogenase
ANCC_RS02070	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ANCC_RS02110	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ANCC_RS02140	COG0514	ATP-dependent DNA helicase (RecQ)
ANCC_RS02145	COG0242	peptide deformylase activity
ANCC_RS02155	COG2186	Transcriptional regulator
ANCC_RS02160	COG0129	dihydroxy-acid dehydratase activity
ANCC_RS02165	COG1063	alcohol dehydrogenase
ANCC_RS02170	COG0436	Aminotransferase
ANCC_RS02175	COG0531	amino acid
ANCC_RS02185	COG1028	Short-chain dehydrogenase reductase Sdr
ANCC_RS02190	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ANCC_RS02195	COG0800	Aldolase
ANCC_RS02200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ANCC_RS02235	COG5001	Diguanylate cyclase
ANCC_RS02235	COG3300	MHYT domain
ANCC_RS02250	COG0534	Mate efflux family protein
ANCC_RS02255	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
ANCC_RS02260	COG0193	aminoacyl-tRNA hydrolase activity
ANCC_RS02265	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ANCC_RS02285	COG0629	single-stranded DNA binding
ANCC_RS02290	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ANCC_RS02295	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
ANCC_RS02300	COG0359	binds to the 23S rRNA
ANCC_RS02305	COG0305	Participates in initiation and elongation during chromosome replication
ANCC_RS02315	COG2768	binding domain, Protein
ANCC_RS02330	COG3414	Phosphotransferase system galactitol-specific IIB component
ANCC_RS02335	COG3775	system Galactitol-specific IIC component
ANCC_RS02340	COG2376	Dihydroxyacetone kinase
ANCC_RS02355	COG2376	Dihydroxyacetone kinase
ANCC_RS02375	COG0673	inositol 2-dehydrogenase activity
ANCC_RS02390	COG0860	N-Acetylmuramoyl-L-alanine amidase
ANCC_RS02395	COG1115	amino acid carrier protein
ANCC_RS02400	COG0009	L-threonylcarbamoyladenylate synthase
ANCC_RS02405	COG0698	ribose 5-phosphate isomerase
ANCC_RS02425	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ANCC_RS02430	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ANCC_RS02435	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ANCC_RS02440	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ANCC_RS02445	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ANCC_RS02450	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ANCC_RS02455	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ANCC_RS02460	COG5001	Diguanylate cyclase
ANCC_RS02465	COG2954	triphosphatase activity
ANCC_RS02470	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ANCC_RS02480	COG0488	(ABC) transporter
ANCC_RS02490	COG0673	inositol 2-dehydrogenase activity
ANCC_RS02495	COG2972	Histidine kinase
ANCC_RS02500	COG4753	response regulator
ANCC_RS02500	COG2207	Transcriptional regulator
ANCC_RS02505	COG1082	Xylose isomerase domain protein TIM barrel
ANCC_RS02525	COG0628	permease
ANCC_RS02535	COG3279	Response regulator of the LytR AlgR family
ANCC_RS02550	COG0432	Pfam Uncharacterised protein family UPF0047
ANCC_RS02555	COG4886	Leucine-rich repeat (LRR) protein
ANCC_RS02560	COG4509	Sortase family
ANCC_RS02580	COG2996	Protein conserved in bacteria
ANCC_RS02585	COG3956	TIGRFAM MazG family protein
ANCC_RS02595	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ANCC_RS02615	COG3711	transcriptional antiterminator
ANCC_RS02615	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANCC_RS02650	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ANCC_RS02680	COG3209	COG3209 Rhs family protein
ANCC_RS02735	COG0446	pyridine nucleotide-disulphide oxidoreductase
ANCC_RS02760	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ANCC_RS02765	COG1301	dicarboxylic acid transport
ANCC_RS02780	COG0534	Mate efflux family protein
ANCC_RS02800	COG1278	Cold shock
ANCC_RS02915	COG0281	malic enzyme
ANCC_RS02925	COG0534	Mate efflux family protein
ANCC_RS02945	COG1640	4-alpha-glucanotransferase
ANCC_RS02950	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ANCC_RS02955	COG2176	DNA-directed DNA polymerase activity
ANCC_RS02960	COG2720	vancomycin resistance protein
ANCC_RS02970	COG1522	sequence-specific DNA binding
ANCC_RS02975	COG0436	Aminotransferase
ANCC_RS02995	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ANCC_RS03000	COG0617	tRNA 3'-terminal CCA addition
ANCC_RS03010	COG1181	Belongs to the D-alanine--D-alanine ligase family
ANCC_RS03015	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ANCC_RS03025	COG0671	phosphoesterase, PA-phosphatase related
ANCC_RS03055	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ANCC_RS03065	COG0646	methionine synthase
ANCC_RS03065	COG1410	methionine synthase
ANCC_RS03070	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ANCC_RS03075	COG1687	branched-chain amino acid
ANCC_RS03085	COG2199	diguanylate cyclase activity
ANCC_RS03155	COG1063	alcohol dehydrogenase
ANCC_RS03160	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ANCC_RS03165	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ANCC_RS03170	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ANCC_RS03175	COG1063	alcohol dehydrogenase
ANCC_RS03180	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ANCC_RS03185	COG1760	l-serine dehydratase
ANCC_RS03190	COG1760	l-serine dehydratase
ANCC_RS03200	COG1737	Transcriptional regulator
ANCC_RS03205	COG1105	Belongs to the carbohydrate kinase PfkB family
ANCC_RS03210	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ANCC_RS03210	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ANCC_RS03210	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANCC_RS03215	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ANCC_RS03215	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ANCC_RS03215	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANCC_RS03220	COG1349	DNA-binding transcription factor activity
ANCC_RS03225	COG1072	(Pantothenic acid kinase))
ANCC_RS03230	COG1063	alcohol dehydrogenase
ANCC_RS03240	COG1408	metallophosphoesterase
ANCC_RS03245	COG1733	regulation of RNA biosynthetic process
ANCC_RS03270	COG0697	spore germination
ANCC_RS03280	COG1691	(AIR) carboxylase
ANCC_RS03285	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
ANCC_RS03290	COG1606	tRNA processing
ANCC_RS03295	COG0310	cobalt ion transport
ANCC_RS03305	COG1122	ATPase activity
ANCC_RS03310	COG0789	Transcriptional regulator
ANCC_RS03320	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ANCC_RS03340	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ANCC_RS03350	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
ANCC_RS03350	COG3933	PFAM sigma-54 factor interaction domain-containing protein
ANCC_RS03365	COG2207	Transcriptional regulator
ANCC_RS03405	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ANCC_RS03410	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ANCC_RS03415	COG1024	Enoyl-CoA hydratase
ANCC_RS03440	COG1979	alcohol dehydrogenase
ANCC_RS03445	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ANCC_RS03450	COG3715	PTS system
ANCC_RS03455	COG3716	PTS system mannose fructose sorbose family IID component
ANCC_RS03465	COG1063	alcohol dehydrogenase
ANCC_RS03475	COG0561	phosphatase activity
ANCC_RS03500	COG1598	PFAM Uncharacterised protein family UPF0150
ANCC_RS03505	COG0038	chloride channel
ANCC_RS03515	COG0561	phosphatase activity
ANCC_RS03525	COG1686	Belongs to the peptidase S11 family
ANCC_RS03540	COG1597	lipid kinase activity
ANCC_RS03560	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ANCC_RS03565	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANCC_RS03570	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
ANCC_RS03570	COG3933	PFAM sigma-54 factor interaction domain-containing protein
ANCC_RS03585	COG1063	alcohol dehydrogenase
ANCC_RS03595	COG3715	PTS system
ANCC_RS03610	COG0667	Aldo Keto reductase
ANCC_RS03630	COG1882	Formate acetyltransferase
ANCC_RS03635	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ANCC_RS03640	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ANCC_RS03645	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ANCC_RS03645	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANCC_RS03650	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ANCC_RS03655	COG3716	PTS system mannose fructose sorbose family IID component
ANCC_RS03660	COG2390	Transcriptional regulator
ANCC_RS03665	COG0657	acetylesterase activity
ANCC_RS03670	COG0512	Glutamine amidotransferase of anthranilate synthase
ANCC_RS03670	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ANCC_RS03675	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ANCC_RS03680	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ANCC_RS03685	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ANCC_RS03690	COG3973	AAA domain
ANCC_RS03695	COG2207	Transcriptional regulator
ANCC_RS03710	COG1115	amino acid carrier protein
ANCC_RS03735	COG0004	ammonium transporteR
ANCC_RS03745	COG0697	spore germination
ANCC_RS03760	COG1959	2 iron, 2 sulfur cluster binding
ANCC_RS03765	COG1511	domain protein
ANCC_RS03785	COG0116	Belongs to the methyltransferase superfamily
ANCC_RS03790	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ANCC_RS03845	COG0596	Alpha beta hydrolase
ANCC_RS03845	COG2945	thiolester hydrolase activity
ANCC_RS03860	COG0513	Belongs to the DEAD box helicase family
ANCC_RS03875	COG2252	PERMEase
ANCC_RS03880	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ANCC_RS03885	COG0784	Response regulator, receiver
ANCC_RS03885	COG2205	protein histidine kinase activity
ANCC_RS03890	COG1929	Belongs to the glycerate kinase type-1 family
ANCC_RS03895	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ANCC_RS03905	COG2198	Histidine kinase
ANCC_RS03905	COG0784	Response regulator, receiver
ANCC_RS03905	COG2205	protein histidine kinase activity
ANCC_RS03925	COG1174	glycine betaine transport
ANCC_RS03930	COG0517	IMP dehydrogenase activity
ANCC_RS03930	COG1125	glycine betaine transport
ANCC_RS03965	COG3732	PTS system glucitol sorbitol-specific
ANCC_RS03970	COG3732	PTS system glucitol sorbitol-specific
ANCC_RS03980	COG2188	Transcriptional regulator
ANCC_RS04000	COG1968	undecaprenyl-diphosphatase activity
ANCC_RS04020	COG1063	alcohol dehydrogenase
ANCC_RS04035	COG1234	tRNA 3'-trailer cleavage
ANCC_RS04045	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ANCC_RS04060	COG0561	phosphatase activity
ANCC_RS04075	COG3437	response regulator, receiver
ANCC_RS04080	COG3885	ferrous iron binding
ANCC_RS04080	COG2078	PFAM AMMECR1 domain protein
ANCC_RS04085	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ANCC_RS04100	COG2202	Pas domain
ANCC_RS04100	COG2200	EAL domain
ANCC_RS04100	COG2199	diguanylate cyclase activity
ANCC_RS04105	COG0768	penicillin binding
ANCC_RS04125	COG0372	Belongs to the citrate synthase family
ANCC_RS04150	COG0460	homoserine dehydrogenase
ANCC_RS04155	COG0697	spore germination
ANCC_RS04175	COG2205	protein histidine kinase activity
ANCC_RS04180	COG0745	RESPONSE REGULATOR receiver
ANCC_RS04185	COG2205	protein histidine kinase activity
ANCC_RS04200	COG0640	Transcriptional regulator
ANCC_RS04205	COG0778	Nitroreductase
ANCC_RS04215	COG0656	L-ascorbic acid biosynthetic process
ANCC_RS04235	COG1136	(ABC) transporter
ANCC_RS04245	COG0745	RESPONSE REGULATOR receiver
ANCC_RS04250	COG0642	Histidine kinase
ANCC_RS04260	COG0723	plastoquinol--plastocyanin reductase activity
ANCC_RS04260	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ANCC_RS04275	COG1331	Highly conserved protein containing a thioredoxin domain
ANCC_RS04290	COG2205	protein histidine kinase activity
ANCC_RS04295	COG1472	Belongs to the glycosyl hydrolase 3 family
ANCC_RS04300	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ANCC_RS04305	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ANCC_RS04310	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ANCC_RS04315	COG1597	lipid kinase activity
ANCC_RS04325	COG1609	Transcriptional regulator
ANCC_RS04335	COG3959	Transketolase, thiamine diphosphate binding domain
ANCC_RS04340	COG3958	Transketolase
ANCC_RS04345	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ANCC_RS04360	COG1368	sulfuric ester hydrolase activity
ANCC_RS04365	COG0544	peptidyl-prolyl cis-trans isomerase activity
ANCC_RS04375	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ANCC_RS04380	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ANCC_RS04385	COG0285	dihydrofolate synthase activity
ANCC_RS04395	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ANCC_RS04400	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ANCC_RS04400	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ANCC_RS04405	COG0077	Prephenate dehydratase
ANCC_RS04405	COG1605	Chorismate mutase
ANCC_RS04410	COG1368	sulfuric ester hydrolase activity
ANCC_RS04415	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ANCC_RS04420	COG0681	Belongs to the peptidase S26 family
ANCC_RS04430	COG0251	oxidation-reduction process
ANCC_RS04435	COG3706	GGDEF domain
ANCC_RS04440	COG0534	Mate efflux family protein
ANCC_RS04445	COG0366	Alpha amylase catalytic
ANCC_RS04450	COG3711	transcriptional antiterminator
ANCC_RS04450	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANCC_RS04455	COG3775	system Galactitol-specific IIC component
ANCC_RS04465	COG3414	Phosphotransferase system galactitol-specific IIB component
ANCC_RS04470	COG1063	alcohol dehydrogenase
ANCC_RS04475	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ANCC_RS04480	COG1063	alcohol dehydrogenase
ANCC_RS04485	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ANCC_RS04490	COG1082	Xylose isomerase domain protein TIM barrel
ANCC_RS04495	COG1105	Belongs to the carbohydrate kinase PfkB family
ANCC_RS04530	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ANCC_RS04530	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ANCC_RS04540	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ANCC_RS04560	COG1609	Transcriptional regulator
ANCC_RS04565	COG2211	Major facilitator Superfamily
ANCC_RS04570	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ANCC_RS04580	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
ANCC_RS04585	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ANCC_RS04600	COG2033	superoxide reductase activity
ANCC_RS04610	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ANCC_RS04615	COG0367	asparagine synthase
ANCC_RS04665	COG2378	regulation of single-species biofilm formation
ANCC_RS04675	COG1464	Belongs to the NlpA lipoprotein family
ANCC_RS04680	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ANCC_RS04685	COG2011	ABC-type metal ion transport system permease component
ANCC_RS04690	COG0277	FAD linked oxidase domain protein
ANCC_RS04700	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ANCC_RS04735	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ANCC_RS04745	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ANCC_RS04755	COG1773	rubredoxin
ANCC_RS04760	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ANCC_RS04765	COG0288	reversible hydration of carbon dioxide
ANCC_RS04770	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ANCC_RS04815	COG1418	mRNA catabolic process
ANCC_RS04825	COG2213	PTS system mannitol-specific
ANCC_RS04825	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANCC_RS04830	COG1349	DNA-binding transcription factor activity
ANCC_RS04835	COG0246	Mannitol dehydrogenase
ANCC_RS04850	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ANCC_RS04865	COG0588	phosphoglycerate mutase activity
ANCC_RS04875	COG1473	amidohydrolase
ANCC_RS04905	COG1131	(ABC) transporter
ANCC_RS04910	COG1725	Transcriptional regulator
ANCC_RS04930	COG0539	negative regulation of cytoplasmic translation
ANCC_RS04935	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ANCC_RS04940	COG0343	queuine tRNA-ribosyltransferase activity
ANCC_RS04945	COG1862	Preprotein translocase
ANCC_RS04950	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ANCC_RS04960	COG0613	PHP domain protein
ANCC_RS04970	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ANCC_RS04975	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ANCC_RS04975	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ANCC_RS04980	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ANCC_RS04980	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ANCC_RS04985	COG0561	phosphatase activity
ANCC_RS04990	COG0420	3'-5' exonuclease activity
ANCC_RS04995	COG0419	ATPase involved in DNA repair
ANCC_RS05035	COG1187	pseudouridine synthase activity
ANCC_RS05040	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ANCC_RS05050	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
ANCC_RS05055	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ANCC_RS05060	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ANCC_RS05060	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ANCC_RS05060	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANCC_RS05075	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ANCC_RS05100	COG1063	alcohol dehydrogenase
ANCC_RS05110	COG3711	transcriptional antiterminator
ANCC_RS05110	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANCC_RS05115	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANCC_RS05120	COG0561	phosphatase activity
ANCC_RS05125	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ANCC_RS05130	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ANCC_RS05135	COG2333	competence protein COMEC
ANCC_RS05135	COG0658	competence protein
ANCC_RS05145	COG0347	Belongs to the P(II) protein family
ANCC_RS05150	COG3842	ATPase activity
ANCC_RS05160	COG1177	transmembrane transport
ANCC_RS05175	COG2267	carboxylic ester hydrolase activity
ANCC_RS05185	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ANCC_RS05200	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ANCC_RS05200	COG0574	Belongs to the PEP-utilizing enzyme family
ANCC_RS05215	COG0148	phosphopyruvate hydratase activity
ANCC_RS05230	COG2199	diguanylate cyclase activity
ANCC_RS05235	COG1321	iron dependent repressor
ANCC_RS05250	COG1918	ferrous iron import across plasma membrane
ANCC_RS05250	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ANCC_RS05290	COG0426	domain, Protein
ANCC_RS05295	COG1960	acyl-CoA dehydrogenase activity
ANCC_RS05310	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ANCC_RS05310	COG2080	2 iron, 2 sulfur cluster binding
ANCC_RS05315	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ANCC_RS05320	COG0673	inositol 2-dehydrogenase activity
ANCC_RS05325	COG1349	DNA-binding transcription factor activity
ANCC_RS05335	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ANCC_RS05360	COG0385	Bile acid
ANCC_RS05365	COG1595	DNA-templated transcription, initiation
ANCC_RS05400	COG1609	Transcriptional regulator
ANCC_RS05415	COG1263	PTS System
ANCC_RS05415	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ANCC_RS05415	COG2190	(PTS) system
ANCC_RS05420	COG1621	beta-fructofuranosidase activity
ANCC_RS05430	COG1695	Transcriptional regulator
ANCC_RS05450	COG2388	GCN5-related N-acetyl-transferase
ANCC_RS05460	COG3414	Phosphotransferase system galactitol-specific IIB component
ANCC_RS05465	COG4989	oxidoreductase activity
ANCC_RS05470	COG3775	system Galactitol-specific IIC component
ANCC_RS05475	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ANCC_RS05485	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANCC_RS05490	COG0371	Dehydrogenase
ANCC_RS05510	COG0432	Pfam Uncharacterised protein family UPF0047
ANCC_RS05515	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ANCC_RS05520	COG2855	membrane
ANCC_RS05530	COG0583	DNA-binding transcription factor activity
ANCC_RS05535	COG1960	acyl-CoA dehydrogenase activity
ANCC_RS05540	COG2086	electron transfer activity
ANCC_RS05545	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ANCC_RS05570	COG0673	inositol 2-dehydrogenase activity
ANCC_RS05585	COG1082	Xylose isomerase domain protein TIM barrel
ANCC_RS05590	COG1082	Xylose isomerase domain protein TIM barrel
ANCC_RS05610	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ANCC_RS05615	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ANCC_RS05625	COG0709	Synthesizes selenophosphate from selenide and ATP
ANCC_RS05635	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ANCC_RS05640	COG1408	metallophosphoesterase
ANCC_RS05650	COG1115	amino acid carrier protein
ANCC_RS05685	COG3906	Belongs to the UPF0473 family
ANCC_RS05690	COG0475	glutathione-regulated potassium exporter activity
ANCC_RS05700	COG3608	succinylglutamate desuccinylase aspartoacylase
ANCC_RS05705	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ANCC_RS05710	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ANCC_RS05715	COG1082	Xylose isomerase domain protein TIM barrel
ANCC_RS05720	COG1917	Cupin 2, conserved barrel domain protein
ANCC_RS05720	COG4977	sequence-specific DNA binding
ANCC_RS05725	COG1082	Xylose isomerase domain protein TIM barrel
ANCC_RS05730	COG0673	inositol 2-dehydrogenase activity
ANCC_RS05735	COG2211	Major facilitator Superfamily
ANCC_RS05740	COG0534	Mate efflux family protein
ANCC_RS05760	COG1349	DNA-binding transcription factor activity
ANCC_RS05765	COG0561	phosphatase activity
ANCC_RS05785	COG0456	acetyltransferase
ANCC_RS05795	COG1773	rubredoxin
ANCC_RS05795	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ANCC_RS05800	COG1609	Transcriptional regulator
ANCC_RS05805	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ANCC_RS05810	COG3962	Belongs to the TPP enzyme family
ANCC_RS05820	COG1454	alcohol dehydrogenase
ANCC_RS05830	COG1942	4-Oxalocrotonate Tautomerase
ANCC_RS05835	COG2086	electron transfer activity
ANCC_RS05840	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ANCC_RS05845	COG2610	gluconate transmembrane transporter activity
ANCC_RS05855	COG1024	Enoyl-CoA hydratase
ANCC_RS05860	COG1960	acyl-CoA dehydrogenase activity
ANCC_RS05870	COG1362	aminopeptidase activity
ANCC_RS05880	COG3842	ATPase activity
ANCC_RS05900	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ANCC_RS05900	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ANCC_RS05915	COG0287	Prephenate dehydrogenase
ANCC_RS05925	COG1649	PFAM Uncharacterised BCR, COG1649
ANCC_RS05930	COG0740	serine-type endopeptidase activity
ANCC_RS05945	COG3414	Phosphotransferase system galactitol-specific IIB component
ANCC_RS05950	COG3775	system Galactitol-specific IIC component
ANCC_RS05955	COG1063	alcohol dehydrogenase
ANCC_RS05970	COG1979	alcohol dehydrogenase
ANCC_RS05980	COG3414	Phosphotransferase system galactitol-specific IIB component
ANCC_RS06010	COG1528	Iron-storage protein
ANCC_RS06025	COG3546	catalase activity
ANCC_RS06030	COG1321	iron dependent repressor
ANCC_RS06040	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ANCC_RS06045	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ANCC_RS06050	COG0569	domain protein
ANCC_RS06055	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ANCC_RS06065	COG0066	3-isopropylmalate dehydratase activity
ANCC_RS06070	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ANCC_RS06075	COG0066	3-isopropylmalate dehydratase activity
ANCC_RS06080	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ANCC_RS06085	COG2059	Chromate
ANCC_RS06095	COG0583	DNA-binding transcription factor activity
ANCC_RS06105	COG0534	Mate efflux family protein
ANCC_RS06135	COG0860	N-Acetylmuramoyl-L-alanine amidase
ANCC_RS06140	COG2267	carboxylic ester hydrolase activity
ANCC_RS06145	COG2239	Acts as a magnesium transporter
ANCC_RS06150	COG0726	polysaccharide deacetylase
ANCC_RS06170	COG1971	Probably functions as a manganese efflux pump
ANCC_RS06180	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ANCC_RS06210	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ANCC_RS06230	COG1739	Uncharacterized protein family UPF0029
ANCC_RS06235	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ANCC_RS06255	COG2184	nucleotidyltransferase activity
ANCC_RS06265	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
ANCC_RS06270	COG1074	ATP-dependent DNA helicase activity
ANCC_RS06285	COG0402	S-adenosylhomocysteine deaminase activity
ANCC_RS06295	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ANCC_RS06300	COG2022	thiamine diphosphate biosynthetic process
ANCC_RS06310	COG0352	thiamine-phosphate diphosphorylase activity
ANCC_RS06320	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ANCC_RS06325	COG4106	trans-aconitate 2-methyltransferase activity
ANCC_RS06330	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ANCC_RS06370	COG1191	sigma factor activity
ANCC_RS06385	COG0006	proline dipeptidase activity
ANCC_RS06390	COG0205	6-phosphofructokinase activity
ANCC_RS06395	COG1295	ribonuclease BN
ANCC_RS06400	COG3711	transcriptional antiterminator
ANCC_RS06410	COG3715	PTS system
ANCC_RS06415	COG3716	PTS system mannose fructose sorbose family IID component
ANCC_RS06425	COG1482	cell wall glycoprotein biosynthetic process
ANCC_RS06430	COG1263	PTS System
ANCC_RS06430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ANCC_RS06430	COG2190	(PTS) system
ANCC_RS06435	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ANCC_RS06440	COG0800	Aldolase
ANCC_RS06445	COG3394	polysaccharide catabolic process
ANCC_RS06450	COG3716	PTS system mannose fructose sorbose family IID component
ANCC_RS06455	COG3715	PTS system
ANCC_RS06460	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ANCC_RS06465	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANCC_RS06475	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ANCC_RS06480	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ANCC_RS06480	COG0072	phenylalanine-tRNA ligase activity
ANCC_RS06495	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ANCC_RS06510	COG4895	conserved protein (DUF2196)
ANCC_RS06530	COG0534	Mate efflux family protein
ANCC_RS06535	COG2081	HI0933 family
ANCC_RS06540	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ANCC_RS06550	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
ANCC_RS06555	COG0740	serine-type endopeptidase activity
ANCC_RS06580	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ANCC_RS06590	COG1058	Belongs to the CinA family
ANCC_RS06590	COG1546	Belongs to the CinA family
ANCC_RS06595	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ANCC_RS06615	COG0488	(ABC) transporter
ANCC_RS06625	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ANCC_RS06630	COG0228	four-way junction DNA binding
ANCC_RS06635	COG1837	Belongs to the UPF0109 family
ANCC_RS06640	COG0708	Exodeoxyribonuclease III
ANCC_RS06665	COG1854	S-ribosylhomocysteine lyase activity
ANCC_RS06715	COG0191	fructose-bisphosphate aldolase activity
ANCC_RS06725	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ANCC_RS06735	COG3716	PTS system mannose fructose sorbose family IID component
ANCC_RS06740	COG1063	alcohol dehydrogenase
ANCC_RS06745	COG2188	Transcriptional regulator
ANCC_RS06750	COG3711	transcriptional antiterminator
ANCC_RS06755	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ANCC_RS06755	COG1263	PTS System
ANCC_RS06755	COG2190	(PTS) system
ANCC_RS06760	COG1263	PTS System
ANCC_RS06760	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ANCC_RS06765	COG0363	glucosamine-6-phosphate deaminase activity
ANCC_RS06770	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ANCC_RS06785	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ANCC_RS06790	COG0631	protein serine/threonine phosphatase activity
ANCC_RS06795	COG1714	RDD family
ANCC_RS06800	COG0515	serine threonine protein kinase
ANCC_RS06800	COG2815	serine threonine protein kinase
ANCC_RS06810	COG2197	response regulator
ANCC_RS06830	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ANCC_RS06845	COG0126	phosphoglycerate kinase activity
ANCC_RS06850	COG0149	triose-phosphate isomerase activity
ANCC_RS06860	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ANCC_RS06865	COG0148	phosphopyruvate hydratase activity
ANCC_RS06880	COG0557	exoribonuclease II activity
ANCC_RS06885	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ANCC_RS06935	COG2205	protein histidine kinase activity
ANCC_RS06955	COG0745	RESPONSE REGULATOR receiver
ANCC_RS06965	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ANCC_RS06970	COG0336	Belongs to the RNA methyltransferase TrmD family
ANCC_RS06975	COG0335	large ribosomal subunit rRNA binding
ANCC_RS06980	COG0681	Belongs to the peptidase S26 family
ANCC_RS06990	COG0681	Belongs to the peptidase S26 family
ANCC_RS06995	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ANCC_RS07000	COG0792	nuclease activity
ANCC_RS07005	COG1496	oxidoreductase activity
ANCC_RS07010	COG1160	GTP binding
ANCC_RS07015	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ANCC_RS07025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ANCC_RS07030	COG0534	Mate efflux family protein
ANCC_RS07035	COG2190	(PTS) system
ANCC_RS07035	COG1263	PTS System
ANCC_RS07035	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ANCC_RS07040	COG2211	Major facilitator Superfamily
ANCC_RS07045	COG2211	Major facilitator Superfamily
ANCC_RS07075	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
ANCC_RS07080	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ANCC_RS07085	COG2357	RelA SpoT domain protein
ANCC_RS07090	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ANCC_RS07090	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
ANCC_RS07095	COG1187	pseudouridine synthase activity
ANCC_RS07100	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ANCC_RS07105	COG1028	Short-chain dehydrogenase reductase Sdr
ANCC_RS07110	COG0564	pseudouridine synthase activity
ANCC_RS07115	COG3331	DNA recombination
ANCC_RS07120	COG1561	YicC-like family, N-terminal region
ANCC_RS07125	COG0194	GDP metabolic process
ANCC_RS07130	COG1758	RNA polymerase activity
ANCC_RS07135	COG1968	undecaprenyl-diphosphatase activity
ANCC_RS07145	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ANCC_RS07150	COG0358	DNA primase activity
ANCC_RS07155	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ANCC_RS07160	COG2384	SAM-dependent methyltransferase
ANCC_RS07230	COG3409	Peptidoglycan-binding domain 1 protein
ANCC_RS07230	COG3773	Cell wall hydrolase
ANCC_RS07245	COG3842	ATPase activity
ANCC_RS07250	COG3645	SOS response
ANCC_RS07260	COG0583	DNA-binding transcription factor activity
ANCC_RS07265	COG3620	sequence-specific DNA binding
ANCC_RS07270	COG0720	synthase
ANCC_RS07275	COG0602	queuosine metabolic process
ANCC_RS07280	COG0302	gtp cyclohydrolase
ANCC_RS07295	COG1733	regulation of RNA biosynthetic process
ANCC_RS07300	COG1335	isochorismatase
ANCC_RS07305	COG1733	regulation of RNA biosynthetic process
ANCC_RS07315	COG0069	glutamate synthase activity
ANCC_RS07315	COG0070	glutamate synthase
ANCC_RS07315	COG0067	glutamate synthase
ANCC_RS07320	COG0493	'glutamate synthase
ANCC_RS07365	COG0628	permease
ANCC_RS07380	COG0028	Belongs to the TPP enzyme family
ANCC_RS07390	COG1959	2 iron, 2 sulfur cluster binding
ANCC_RS07395	COG0534	Mate efflux family protein
ANCC_RS07405	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ANCC_RS07405	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ANCC_RS07410	COG0237	dephospho-CoA kinase activity
ANCC_RS07415	COG0456	acetyltransferase
ANCC_RS07425	COG1595	DNA-templated transcription, initiation
ANCC_RS07430	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ANCC_RS07445	COG2195	Cleaves the N-terminal amino acid of tripeptides
ANCC_RS07450	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ANCC_RS07475	COG0484	heat shock protein binding
ANCC_RS07480	COG0443	Heat shock 70 kDa protein
ANCC_RS07485	COG1420	regulation of RNA biosynthetic process
ANCC_RS07490	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ANCC_RS07495	COG0443	Heat shock 70 kDa protein
ANCC_RS07500	COG0484	heat shock protein binding
ANCC_RS07505	COG0561	phosphatase activity
ANCC_RS07535	COG3263	regulation of cellular component size
ANCC_RS07545	COG2264	protein methyltransferase activity
ANCC_RS07550	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ANCC_RS07555	COG1104	cysteine desulfurase activity
ANCC_RS07570	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ANCC_RS07575	COG4472	Bacterial protein of unknown function (DUF965)
ANCC_RS07580	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ANCC_RS07590	COG0735	belongs to the Fur family
ANCC_RS07595	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ANCC_RS07605	COG4122	O-methyltransferase activity
ANCC_RS07610	COG0826	peptidase U32
ANCC_RS07630	COG1309	transcriptional regulator
ANCC_RS07645	COG0745	RESPONSE REGULATOR receiver
ANCC_RS07650	COG5002	protein histidine kinase activity
ANCC_RS07660	COG1876	peptidase activity
ANCC_RS07695	COG2226	methyltransferase
ANCC_RS07710	COG0346	lactoylglutathione lyase activity
ANCC_RS07720	COG0583	DNA-binding transcription factor activity
ANCC_RS07730	COG2814	Major facilitator Superfamily
ANCC_RS07745	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ANCC_RS07745	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ANCC_RS07750	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ANCC_RS07760	COG2207	Transcriptional regulator
ANCC_RS07760	COG1917	Cupin 2, conserved barrel domain protein
ANCC_RS07765	COG2271	Major facilitator Superfamily
ANCC_RS07770	COG4670	ketone body catabolic process
ANCC_RS07775	COG2030	dehydratase
ANCC_RS07780	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ANCC_RS07790	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ANCC_RS07805	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
ANCC_RS07810	COG3428	Bacterial PH domain
ANCC_RS07815	COG3428	Bacterial PH domain
ANCC_RS07825	COG0583	DNA-binding transcription factor activity
ANCC_RS07830	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ANCC_RS07835	COG1979	alcohol dehydrogenase
ANCC_RS07850	COG3854	ATPases associated with a variety of cellular activities
ANCC_RS07890	COG1302	Protein conserved in bacteria
ANCC_RS07895	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ANCC_RS07900	COG1570	exodeoxyribonuclease VII activity
ANCC_RS07905	COG1722	exodeoxyribonuclease VII activity
ANCC_RS07915	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ANCC_RS07920	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
ANCC_RS07925	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ANCC_RS07930	COG1438	arginine binding
ANCC_RS07935	COG0497	DNA recombination
ANCC_RS07940	COG0750	zinc metalloprotease
ANCC_RS07945	COG0745	RESPONSE REGULATOR receiver
ANCC_RS07950	COG0745	RESPONSE REGULATOR receiver
ANCC_RS07955	COG1293	RNA-binding protein homologous to eukaryotic snRNP
ANCC_RS07965	COG0124	histidyl-tRNA synthetase
ANCC_RS07970	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ANCC_RS07975	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ANCC_RS07980	COG0131	Imidazoleglycerol-phosphate dehydratase
ANCC_RS07995	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ANCC_RS08010	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ANCC_RS08025	COG1702	phosphate starvation-inducible protein PhoH
ANCC_RS08030	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ANCC_RS08035	COG0728	peptidoglycan biosynthetic process
ANCC_RS08050	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
ANCC_RS08055	COG2081	HI0933 family
ANCC_RS08060	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
ANCC_RS08065	COG1328	CTP reductase activity
ANCC_RS08070	COG0602	queuosine metabolic process
ANCC_RS08075	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ANCC_RS08080	COG4224	UPF0291 protein
ANCC_RS08090	COG4656	Part of a membrane complex involved in electron transport
ANCC_RS08095	COG4658	electron transport chain
ANCC_RS08100	COG4659	FMN binding
ANCC_RS08105	COG4660	Part of a membrane complex involved in electron transport
ANCC_RS08110	COG4657	Part of a membrane complex involved in electron transport
ANCC_RS08115	COG2878	Part of a membrane complex involved in electron transport
ANCC_RS08120	COG1873	PFAM PRC-barrel domain
ANCC_RS08125	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ANCC_RS08130	COG0606	chelatase, subunit chli
ANCC_RS08135	COG0758	DNA mediated transformation
ANCC_RS08140	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ANCC_RS08150	COG0052	Belongs to the universal ribosomal protein uS2 family
ANCC_RS08155	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ANCC_RS08160	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ANCC_RS08165	COG2226	methyltransferase
ANCC_RS08170	COG5002	protein histidine kinase activity
ANCC_RS08170	COG3447	MASE1 domain protein
ANCC_RS08170	COG5001	Diguanylate cyclase
ANCC_RS08175	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ANCC_RS08180	COG0519	Catalyzes the synthesis of GMP from XMP
ANCC_RS08185	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANCC_RS08200	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ANCC_RS08235	COG5001	Diguanylate cyclase
ANCC_RS08235	COG3447	MASE1 domain protein
ANCC_RS08235	COG5002	protein histidine kinase activity
ANCC_RS08240	COG3300	MHYT domain
ANCC_RS08240	COG5001	Diguanylate cyclase
ANCC_RS08245	COG5002	protein histidine kinase activity
ANCC_RS08245	COG2205	protein histidine kinase activity
ANCC_RS08245	COG0784	Response regulator, receiver
ANCC_RS08250	COG0561	phosphatase activity
ANCC_RS08285	COG1122	ATPase activity
ANCC_RS08295	COG0135	phosphoribosylanthranilate isomerase activity
ANCC_RS08300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ANCC_RS08305	COG1957	nucleoside hydrolase
ANCC_RS08315	COG1979	alcohol dehydrogenase
ANCC_RS08320	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ANCC_RS08335	COG1349	DNA-binding transcription factor activity
ANCC_RS08340	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ANCC_RS08345	COG1882	Formate acetyltransferase
ANCC_RS08355	COG0673	inositol 2-dehydrogenase activity
ANCC_RS08360	COG4702	Belongs to the UPF0303 family
ANCC_RS08365	COG0745	RESPONSE REGULATOR receiver
ANCC_RS08370	COG2205	protein histidine kinase activity
ANCC_RS08390	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
ANCC_RS08410	COG3711	transcriptional antiterminator
ANCC_RS08415	COG0246	Mannitol dehydrogenase
ANCC_RS08420	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
ANCC_RS08425	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ANCC_RS08430	COG1979	alcohol dehydrogenase
ANCC_RS08450	COG0371	Dehydrogenase
ANCC_RS08460	COG1063	alcohol dehydrogenase
ANCC_RS08465	COG3414	Phosphotransferase system galactitol-specific IIB component
ANCC_RS08470	COG3775	system Galactitol-specific IIC component
ANCC_RS08480	COG3711	transcriptional antiterminator
ANCC_RS08480	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANCC_RS08485	COG3620	sequence-specific DNA binding
ANCC_RS08500	COG0640	Transcriptional regulator
ANCC_RS08510	COG2217	Heavy metal translocating P-type atpase
ANCC_RS08515	COG1309	transcriptional regulator
ANCC_RS08520	COG1132	(ABC) transporter
ANCC_RS08530	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ANCC_RS08540	COG0181	hydroxymethylbilane synthase activity
ANCC_RS08545	COG0113	porphobilinogen synthase activity
ANCC_RS08550	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ANCC_RS08555	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
ANCC_RS08590	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
ANCC_RS08600	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
ANCC_RS08620	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ANCC_RS08655	COG1309	transcriptional regulator
ANCC_RS08660	COG0534	Mate efflux family protein
ANCC_RS08680	COG5566	PFAM Mor transcription activator
ANCC_RS08715	COG1309	transcriptional regulator
ANCC_RS08740	COG0534	Mate efflux family protein
ANCC_RS08750	COG1122	ATPase activity
ANCC_RS08765	COG0310	cobalt ion transport
ANCC_RS08795	COG1011	Hydrolase
ANCC_RS08810	COG1269	ATP hydrolysis coupled proton transport
ANCC_RS08830	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
ANCC_RS08840	COG1394	ATPase activity, coupled to movement of substances
ANCC_RS08850	COG1012	belongs to the aldehyde dehydrogenase family
ANCC_RS08860	COG0426	domain, Protein
ANCC_RS08880	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ANCC_RS08885	COG0402	S-adenosylhomocysteine deaminase activity
ANCC_RS08890	COG1490	D-aminoacyl-tRNA deacylase activity
ANCC_RS08895	COG0528	UMP kinase activity
ANCC_RS08900	COG0233	cytoplasmic translational termination
ANCC_RS08910	COG4589	Belongs to the CDS family
ANCC_RS08915	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ANCC_RS08920	COG0750	zinc metalloprotease
ANCC_RS08925	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ANCC_RS08935	COG2199	diguanylate cyclase activity
ANCC_RS08935	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ANCC_RS08945	COG1937	Protein conserved in bacteria
ANCC_RS08955	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ANCC_RS08960	COG0022	dehydrogenase e1 component
ANCC_RS08965	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ANCC_RS08970	COG0508	dehydrogenase complex catalyzes the overall conversion of
ANCC_RS08980	COG1063	alcohol dehydrogenase
ANCC_RS08985	COG3414	Phosphotransferase system galactitol-specific IIB component
ANCC_RS08995	COG3775	system Galactitol-specific IIC component
ANCC_RS09005	COG1850	ribulose-bisphosphate carboxylase activity
ANCC_RS09015	COG0095	Lipoate-protein ligase
ANCC_RS09030	COG1121	(ABC) transporter
ANCC_RS09035	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ANCC_RS09055	COG0779	Required for maturation of 30S ribosomal subunits
ANCC_RS09060	COG0195	Participates in both transcription termination and antitermination
ANCC_RS09065	COG2740	Nucleic-acid-binding protein implicated in transcription termination
ANCC_RS09075	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ANCC_RS09080	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ANCC_RS09085	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ANCC_RS09090	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ANCC_RS09095	COG0196	riboflavin kinase activity
ANCC_RS09115	COG1304	FMN binding
ANCC_RS09125	COG5002	protein histidine kinase activity
ANCC_RS09125	COG0784	Response regulator, receiver
ANCC_RS09125	COG2205	protein histidine kinase activity
ANCC_RS09130	COG4974	Belongs to the 'phage' integrase family
ANCC_RS09160	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ANCC_RS09180	COG0037	tRNA processing
ANCC_RS09200	COG0789	Transcriptional regulator
ANCC_RS09210	COG1012	belongs to the aldehyde dehydrogenase family
ANCC_RS09215	COG0148	phosphopyruvate hydratase activity
ANCC_RS09225	COG0191	fructose-bisphosphate aldolase activity
ANCC_RS09230	COG1349	DNA-binding transcription factor activity
ANCC_RS09235	COG1063	alcohol dehydrogenase
ANCC_RS09240	COG3716	PTS system mannose fructose sorbose family IID component
ANCC_RS09250	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ANCC_RS09260	COG1349	DNA-binding transcription factor activity
ANCC_RS09305	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ANCC_RS09310	COG0187	DNA topoisomerase II activity
ANCC_RS09315	COG2200	EAL domain
ANCC_RS09335	COG2155	Conserved Protein
ANCC_RS09355	COG1533	DNA photolyase activity
ANCC_RS09365	COG1473	amidohydrolase
ANCC_RS09370	COG1473	amidohydrolase
ANCC_RS09420	COG1131	(ABC) transporter
ANCC_RS09425	COG0789	Transcriptional regulator
ANCC_RS09450	COG2378	regulation of single-species biofilm formation
ANCC_RS09475	COG1979	alcohol dehydrogenase
ANCC_RS09485	COG3716	PTS system mannose fructose sorbose family IID component
ANCC_RS09490	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ANCC_RS09495	COG1063	alcohol dehydrogenase
ANCC_RS09505	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ANCC_RS09515	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ANCC_RS09520	COG0551	DNA topoisomerase type I activity
ANCC_RS09520	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ANCC_RS09530	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ANCC_RS09535	COG3706	GGDEF domain
ANCC_RS09545	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ANCC_RS09550	COG0527	aspartate kinase activity
ANCC_RS09555	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ANCC_RS09565	COG0277	FAD linked oxidase domain protein
ANCC_RS09575	COG2086	electron transfer activity
ANCC_RS09580	COG2186	Transcriptional regulator
ANCC_RS09585	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ANCC_RS09605	COG3875	lactate racemase activity
ANCC_RS09610	COG1620	l-lactate permease
ANCC_RS09615	COG0124	histidyl-tRNA synthetase
ANCC_RS09625	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ANCC_RS09630	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ANCC_RS09635	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ANCC_RS09645	COG0540	Belongs to the ATCase OTCase family
ANCC_RS09655	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ANCC_RS09665	COG4968	Prepilin-type N-terminal cleavage methylation domain
ANCC_RS09670	COG1408	metallophosphoesterase
ANCC_RS09685	COG1733	regulation of RNA biosynthetic process
ANCC_RS09695	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ANCC_RS09700	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ANCC_RS09735	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ANCC_RS09740	COG0745	RESPONSE REGULATOR receiver
ANCC_RS09780	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ANCC_RS09795	COG1459	type II secretion system
ANCC_RS09800	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ANCC_RS09870	COG0745	RESPONSE REGULATOR receiver
ANCC_RS09875	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ANCC_RS09880	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ANCC_RS09895	COG2738	Putative neutral zinc metallopeptidase
ANCC_RS09905	COG0217	transcriptional regulatory protein
ANCC_RS09910	COG1253	flavin adenine dinucleotide binding
ANCC_RS09915	COG2337	Toxic component of a toxin-antitoxin (TA) module
ANCC_RS09920	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ANCC_RS09925	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ANCC_RS09925	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ANCC_RS09930	COG0736	holo-[acyl-carrier-protein] synthase activity
ANCC_RS09935	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
ANCC_RS09940	COG0488	(ABC) transporter
ANCC_RS09945	COG1215	transferase activity, transferring glycosyl groups
ANCC_RS09950	COG0789	Transcriptional regulator
ANCC_RS09955	COG1131	(ABC) transporter
ANCC_RS09965	COG1404	Belongs to the peptidase S8 family
ANCC_RS09970	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ANCC_RS09975	COG0481	GTPase activity
ANCC_RS09985	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ANCC_RS09990	COG0268	Binds directly to 16S ribosomal RNA
ANCC_RS10000	COG0583	DNA-binding transcription factor activity
ANCC_RS10005	COG2068	MobA-Related Protein
ANCC_RS10010	COG0658	competence protein
ANCC_RS10010	COG2333	competence protein COMEC
ANCC_RS10025	COG0745	RESPONSE REGULATOR receiver
ANCC_RS10040	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ANCC_RS10045	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ANCC_RS10050	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ANCC_RS10055	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ANCC_RS10060	COG0137	argininosuccinate synthase activity
ANCC_RS10065	COG2949	membrane
ANCC_RS10070	COG0551	DNA topoisomerase type I activity
ANCC_RS10070	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ANCC_RS10075	COG3177	Filamentation induced by cAMP protein fic
ANCC_RS10075	COG0666	response to abiotic stimulus
ANCC_RS10085	COG0165	Argininosuccinate lyase
ANCC_RS10095	COG2226	methyltransferase
ANCC_RS10115	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ANCC_RS10120	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ANCC_RS10125	COG0028	Belongs to the TPP enzyme family
ANCC_RS10130	COG0129	dihydroxy-acid dehydratase activity
ANCC_RS10135	COG0473	3-isopropylmalate dehydrogenase activity
ANCC_RS10150	COG0860	N-Acetylmuramoyl-L-alanine amidase
ANCC_RS10155	COG0860	N-Acetylmuramoyl-L-alanine amidase
ANCC_RS10165	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ANCC_RS10180	COG0799	negative regulation of ribosome biogenesis
ANCC_RS10185	COG1713	HD superfamily hydrolase involved in NAD metabolism
ANCC_RS10190	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ANCC_RS10195	COG1534	Rna-binding protein
ANCC_RS10200	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ANCC_RS10205	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ANCC_RS10220	COG1530	ribonuclease E activity
ANCC_RS10225	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ANCC_RS10250	COG2205	protein histidine kinase activity
ANCC_RS10250	COG0784	Response regulator, receiver
ANCC_RS10250	COG2198	Histidine kinase
ANCC_RS10270	COG0714	Associated with various cellular activities
ANCC_RS10275	COG1757	Na H antiporter
ANCC_RS10280	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ANCC_RS10290	COG0351	phosphomethylpyrimidine kinase
ANCC_RS10290	COG0352	thiamine-phosphate diphosphorylase activity
ANCC_RS10300	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
ANCC_RS10335	COG1136	(ABC) transporter
ANCC_RS10345	COG0745	RESPONSE REGULATOR receiver
ANCC_RS10380	COG1979	alcohol dehydrogenase
ANCC_RS10385	COG0667	Aldo Keto reductase
ANCC_RS10415	COG3708	Transcriptional regulator
ANCC_RS10415	COG2207	Transcriptional regulator
ANCC_RS10465	COG0561	phosphatase activity
ANCC_RS10475	COG1376	ErfK ybiS ycfS ynhG family protein
ANCC_RS10485	COG1362	aminopeptidase activity
ANCC_RS10490	COG1393	Belongs to the ArsC family
ANCC_RS10495	COG1686	Belongs to the peptidase S11 family
ANCC_RS10500	COG2199	diguanylate cyclase activity
ANCC_RS10505	COG5001	Diguanylate cyclase
ANCC_RS10505	COG3300	MHYT domain
ANCC_RS10510	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
ANCC_RS10520	COG0427	acetyl-CoA hydrolase
ANCC_RS10525	COG0039	L-malate dehydrogenase activity
ANCC_RS10565	COG2723	6-phospho-beta-galactosidase activity
ANCC_RS10575	COG1454	alcohol dehydrogenase
ANCC_RS10580	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ANCC_RS10585	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ANCC_RS10600	COG1454	alcohol dehydrogenase
ANCC_RS10605	COG1349	DNA-binding transcription factor activity
ANCC_RS10615	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
ANCC_RS10620	COG3300	MHYT domain
ANCC_RS10620	COG5001	Diguanylate cyclase
ANCC_RS10625	COG5001	Diguanylate cyclase
ANCC_RS10625	COG3300	MHYT domain
ANCC_RS10630	COG2199	diguanylate cyclase activity
ANCC_RS10635	COG0739	heme binding
ANCC_RS10655	COG3706	GGDEF domain
ANCC_RS10655	COG5001	Diguanylate cyclase
ANCC_RS10655	COG4251	negative regulation of phosphorylation
ANCC_RS10655	COG2203	Gaf domain
ANCC_RS10670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ANCC_RS10690	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ANCC_RS10700	COG3620	sequence-specific DNA binding
ANCC_RS10710	COG2086	electron transfer activity
ANCC_RS10715	COG1960	acyl-CoA dehydrogenase activity
ANCC_RS10720	COG1250	3-hydroxyacyl-CoA dehydrogenase
ANCC_RS10725	COG1024	Enoyl-CoA hydratase
ANCC_RS10730	COG0183	Belongs to the thiolase family
ANCC_RS10740	COG0071	Belongs to the small heat shock protein (HSP20) family
ANCC_RS10745	COG0440	acetolactate synthase activity
ANCC_RS10750	COG0028	Belongs to the TPP enzyme family
ANCC_RS10755	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ANCC_RS10765	COG1408	metallophosphoesterase
ANCC_RS10775	COG3732	PTS system glucitol sorbitol-specific
ANCC_RS10780	COG3730	PTS system glucitol sorbitol-specific
ANCC_RS10790	COG3711	transcriptional antiterminator
ANCC_RS10790	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANCC_RS10800	COG1686	Belongs to the peptidase S11 family
ANCC_RS10810	COG0768	penicillin binding
ANCC_RS10820	COG0826	peptidase U32
ANCC_RS10830	COG2255	four-way junction helicase activity
ANCC_RS10835	COG0632	four-way junction helicase activity
ANCC_RS10850	COG1346	cytolysis
ANCC_RS10855	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ANCC_RS10870	COG2002	toxin-antitoxin pair type II binding
ANCC_RS10885	COG2873	o-acetylhomoserine
ANCC_RS10895	COG4120	Belongs to the binding-protein-dependent transport system permease family
ANCC_RS10910	COG1185	polyribonucleotide nucleotidyltransferase activity
ANCC_RS10915	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ANCC_RS10920	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ANCC_RS10925	COG0564	pseudouridine synthase activity
ANCC_RS10930	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ANCC_RS10935	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ANCC_RS10950	COG1799	cell septum assembly
ANCC_RS10955	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ANCC_RS10965	COG1242	4 iron, 4 sulfur cluster binding
ANCC_RS10970	COG1686	Belongs to the peptidase S11 family
ANCC_RS10975	COG1803	Methylglyoxal synthase
ANCC_RS10980	COG0772	Belongs to the SEDS family
ANCC_RS10985	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
ANCC_RS10990	COG2894	cell division
ANCC_RS10995	COG0850	regulation of cytokinetic process
ANCC_RS11000	COG0768	penicillin binding
ANCC_RS11015	COG1077	Cell shape determining protein MreB Mrl
ANCC_RS11020	COG2003	Belongs to the UPF0758 family
ANCC_RS11025	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
ANCC_RS11030	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ANCC_RS11035	COG0295	cytidine deaminase activity
ANCC_RS11045	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ANCC_RS11050	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ANCC_RS11055	COG0562	UDP-galactopyranose mutase
ANCC_RS11060	COG1283	sodium-dependent phosphate transmembrane transporter activity
ANCC_RS11070	COG0058	SHG alpha-glucan phosphorylase activity
ANCC_RS11075	COG0297	glycogen (starch) synthase activity
ANCC_RS11080	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ANCC_RS11085	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ANCC_RS11095	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ANCC_RS11100	COG0552	protein localization to endoplasmic reticulum
ANCC_RS11105	COG1196	nuclear chromosome segregation
ANCC_RS11110	COG0571	ribonuclease III activity
ANCC_RS11115	COG0416	fatty acid biosynthetic process
ANCC_RS11120	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ANCC_RS11130	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ANCC_RS11135	COG0280	phosphate acetyltransferase
ANCC_RS11140	COG1323	Belongs to the UPF0348 family
ANCC_RS11145	COG3314	Sporulation integral membrane protein YlbJ
ANCC_RS11155	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ANCC_RS11160	COG0742	ribosomal rna small subunit methyltransferase
ANCC_RS11170	COG1874	Beta-galactosidase
ANCC_RS11180	COG2376	Dihydroxyacetone kinase
ANCC_RS11185	COG1461	Dihydroxyacetone kinase
ANCC_RS11190	COG1082	Xylose isomerase domain protein TIM barrel
ANCC_RS11215	COG1254	Belongs to the acylphosphatase family
ANCC_RS11220	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ANCC_RS11225	COG1461	Dihydroxyacetone kinase
ANCC_RS11235	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ANCC_RS11285	COG0583	DNA-binding transcription factor activity
ANCC_RS11295	COG1725	Transcriptional regulator
ANCC_RS11300	COG1131	(ABC) transporter
ANCC_RS11315	COG0107	imidazoleglycerol-phosphate synthase activity
ANCC_RS11320	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ANCC_RS11330	COG5002	protein histidine kinase activity
ANCC_RS11335	COG0745	RESPONSE REGULATOR receiver
ANCC_RS11345	COG0561	phosphatase activity
ANCC_RS11355	COG0482	sulfurtransferase activity
ANCC_RS11360	COG0822	iron-sulfur transferase activity
ANCC_RS11370	COG1959	2 iron, 2 sulfur cluster binding
ANCC_RS11375	COG2244	polysaccharide biosynthetic process
ANCC_RS11380	COG1079	Belongs to the binding-protein-dependent transport system permease family
ANCC_RS11385	COG4603	Belongs to the binding-protein-dependent transport system permease family
ANCC_RS11390	COG3845	ABC transporter
ANCC_RS11430	COG1595	DNA-templated transcription, initiation
ANCC_RS11435	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ANCC_RS11445	COG0215	cysteine-tRNA ligase activity
ANCC_RS11450	COG1045	serine acetyltransferase
ANCC_RS11465	COG1268	BioY protein
ANCC_RS11470	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ANCC_RS11485	COG2198	Histidine kinase
ANCC_RS11485	COG2205	protein histidine kinase activity
ANCC_RS11485	COG0784	Response regulator, receiver
ANCC_RS11490	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ANCC_RS11495	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ANCC_RS11500	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ANCC_RS11505	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ANCC_RS11510	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ANCC_RS11515	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ANCC_RS11520	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ANCC_RS11530	COG0356	it plays a direct role in the translocation of protons across the membrane
ANCC_RS11575	COG0210	DNA helicase
ANCC_RS11585	COG4496	protein, YerC YecD
ANCC_RS11590	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ANCC_RS11605	COG1131	(ABC) transporter
ANCC_RS11610	COG4585	Histidine kinase
ANCC_RS11615	COG2197	response regulator
ANCC_RS11620	COG4536	flavin adenine dinucleotide binding
ANCC_RS11630	COG0210	DNA helicase
ANCC_RS11635	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ANCC_RS11640	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ANCC_RS11670	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANCC_RS11675	COG3711	transcriptional antiterminator
ANCC_RS11680	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ANCC_RS11690	COG1349	DNA-binding transcription factor activity
ANCC_RS11700	COG1882	Formate acetyltransferase
ANCC_RS11705	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ANCC_RS11705	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANCC_RS11705	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ANCC_RS11740	COG1737	Transcriptional regulator
ANCC_RS11760	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANCC_RS11760	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ANCC_RS11765	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANCC_RS11775	COG0534	Mate efflux family protein
ANCC_RS11785	COG0725	ABC transporter, periplasmic molybdate-binding protein
ANCC_RS11790	COG4149	molybdate abc transporter
ANCC_RS11800	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ANCC_RS11805	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ANCC_RS11805	COG3608	succinylglutamate desuccinylase aspartoacylase
ANCC_RS11820	COG1131	(ABC) transporter
ANCC_RS11825	COG1309	transcriptional regulator
ANCC_RS11830	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ANCC_RS11840	COG1132	(ABC) transporter
ANCC_RS11865	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ANCC_RS11875	COG1131	(ABC) transporter
ANCC_RS11900	COG5001	Diguanylate cyclase
ANCC_RS11900	COG3300	MHYT domain
ANCC_RS11915	COG0521	Mo-molybdopterin cofactor biosynthetic process
ANCC_RS11935	COG3608	succinylglutamate desuccinylase aspartoacylase
ANCC_RS11935	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ANCC_RS11955	COG0493	'glutamate synthase
ANCC_RS11955	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ANCC_RS11960	COG0402	S-adenosylhomocysteine deaminase activity
ANCC_RS11975	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ANCC_RS11980	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ANCC_RS11985	COG0549	Belongs to the carbamate kinase family
ANCC_RS12030	COG3620	sequence-specific DNA binding
ANCC_RS12040	COG0791	NLP P60 protein
ANCC_RS12040	COG3883	PFAM NLP P60 protein
ANCC_RS12060	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ANCC_RS12080	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANCC_RS12080	COG3711	transcriptional antiterminator
ANCC_RS12085	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ANCC_RS12095	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ANCC_RS12100	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ANCC_RS12125	COG2378	regulation of single-species biofilm formation
ANCC_RS12150	COG0546	phosphoglycolate phosphatase activity
ANCC_RS12155	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
ANCC_RS12160	COG1105	Belongs to the carbohydrate kinase PfkB family
ANCC_RS12165	COG1063	alcohol dehydrogenase
ANCC_RS12175	COG3775	system Galactitol-specific IIC component
ANCC_RS12180	COG3414	Phosphotransferase system galactitol-specific IIB component
ANCC_RS12190	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANCC_RS12190	COG3711	transcriptional antiterminator
ANCC_RS12200	COG0577	efflux transmembrane transporter activity
ANCC_RS12205	COG1136	(ABC) transporter
ANCC_RS12205	COG0577	efflux transmembrane transporter activity
ANCC_RS12210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ANCC_RS12220	COG1242	4 iron, 4 sulfur cluster binding
ANCC_RS12240	COG0371	Dehydrogenase
ANCC_RS12245	COG0698	ribose 5-phosphate isomerase
ANCC_RS12250	COG3732	PTS system glucitol sorbitol-specific
ANCC_RS12255	COG3730	PTS system glucitol sorbitol-specific
ANCC_RS12270	COG0561	phosphatase activity
ANCC_RS12280	COG0154	amidase activity
ANCC_RS12285	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ANCC_RS12315	COG0515	serine threonine protein kinase
ANCC_RS12315	COG2815	serine threonine protein kinase
ANCC_RS12320	COG0631	protein serine/threonine phosphatase activity
ANCC_RS12325	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ANCC_RS12330	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ANCC_RS12330	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ANCC_RS12335	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ANCC_RS12340	COG0242	peptide deformylase activity
ANCC_RS12345	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ANCC_RS12350	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ANCC_RS12355	COG0735	belongs to the Fur family
ANCC_RS12360	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ANCC_RS12365	COG0688	phosphatidylethanolamine metabolic process
ANCC_RS12370	COG1183	phosphatidylcholine synthase activity
ANCC_RS12385	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ANCC_RS12395	COG0516	GMP reductase activity
ANCC_RS12395	COG0517	IMP dehydrogenase activity
ANCC_RS12405	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ANCC_RS12405	COG0493	'glutamate synthase
ANCC_RS12420	COG0459	protein refolding
ANCC_RS12425	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ANCC_RS12430	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ANCC_RS12435	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ANCC_RS12440	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ANCC_RS12450	COG0542	response to heat
ANCC_RS12460	COG0151	Belongs to the GarS family
ANCC_RS12465	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ANCC_RS12470	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ANCC_RS12480	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ANCC_RS12505	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ANCC_RS12515	COG0167	dihydroorotate dehydrogenase activity
ANCC_RS12520	COG0543	2 iron, 2 sulfur cluster binding
ANCC_RS12525	COG0284	orotidine-5'-phosphate decarboxylase activity
ANCC_RS12530	COG5002	protein histidine kinase activity
ANCC_RS12540	COG0704	Plays a role in the regulation of phosphate uptake
ANCC_RS12545	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ANCC_RS12550	COG0581	inorganic phosphate transmembrane transporter activity
ANCC_RS12555	COG0573	inorganic phosphate transmembrane transporter activity
ANCC_RS12570	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ANCC_RS12580	COG3290	protein histidine kinase activity
ANCC_RS12580	COG3829	transcription factor binding
ANCC_RS12610	COG0423	glycine-tRNA ligase activity
ANCC_RS12615	COG1381	Involved in DNA repair and RecF pathway recombination
ANCC_RS12620	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ANCC_RS12645	COG0789	Transcriptional regulator
ANCC_RS12675	COG3757	hydrolase, family 25
ANCC_RS12680	COG1191	sigma factor activity
ANCC_RS12690	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ANCC_RS12700	COG0772	Belongs to the SEDS family
ANCC_RS12705	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ANCC_RS12715	COG0768	penicillin binding
ANCC_RS12720	COG0768	penicillin binding
ANCC_RS12730	COG0275	rRNA processing
ANCC_RS12735	COG2001	Belongs to the MraZ family
ANCC_RS12740	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ANCC_RS12745	COG0012	GTP binding
ANCC_RS12750	COG0791	NLP P60 protein
ANCC_RS12755	COG0436	Aminotransferase
ANCC_RS12770	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ANCC_RS12785	COG1132	(ABC) transporter
ANCC_RS12790	COG0393	Putative heavy-metal-binding
ANCC_RS12840	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
ANCC_RS12845	COG1518	maintenance of DNA repeat elements
ANCC_RS12885	COG0275	rRNA processing
ANCC_RS12895	COG4978	Transcriptional regulator
ANCC_RS12895	COG0789	Transcriptional regulator
ANCC_RS12910	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ANCC_RS12935	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ANCC_RS12940	COG0436	Aminotransferase
ANCC_RS12945	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ANCC_RS12950	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ANCC_RS12955	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
ANCC_RS12965	COG1217	gtp-binding protein TYPA
ANCC_RS12975	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ANCC_RS12990	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
ANCC_RS12995	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ANCC_RS13000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ANCC_RS13010	COG0673	inositol 2-dehydrogenase activity
ANCC_RS13015	COG1132	(ABC) transporter
ANCC_RS13025	COG1846	Transcriptional regulator
ANCC_RS13045	COG0653	protein targeting
ANCC_RS13050	COG0640	Transcriptional regulator
ANCC_RS13055	COG0701	Predicted permease
ANCC_RS13060	COG2365	Tyrosine phosphatase family
ANCC_RS13070	COG0656	L-ascorbic acid biosynthetic process
ANCC_RS13075	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ANCC_RS13085	COG1609	Transcriptional regulator
ANCC_RS13090	COG1686	Belongs to the peptidase S11 family
ANCC_RS13100	COG0523	cobalamin synthesis protein
ANCC_RS13120	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ANCC_RS13125	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
ANCC_RS13130	COG2080	2 iron, 2 sulfur cluster binding
ANCC_RS13150	COG1349	DNA-binding transcription factor activity
ANCC_RS13155	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANCC_RS13155	COG2213	PTS system mannitol-specific
ANCC_RS13160	COG0673	inositol 2-dehydrogenase activity
ANCC_RS13165	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ANCC_RS13175	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ANCC_RS13180	COG2890	protein-(glutamine-N5) methyltransferase activity
ANCC_RS13185	COG3872	metal-dependent enzyme
ANCC_RS13190	COG0254	rRNA binding
ANCC_RS13195	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ANCC_RS13205	COG2172	sigma factor antagonist activity
ANCC_RS13225	COG0285	dihydrofolate synthase activity
ANCC_RS13230	COG0525	valine-tRNA ligase activity
ANCC_RS13255	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ANCC_RS13280	COG0372	Belongs to the citrate synthase family
ANCC_RS13285	COG4598	ABC transporter
ANCC_RS13295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ANCC_RS13305	COG4193	domain, Protein
ANCC_RS13320	COG1595	DNA-templated transcription, initiation
ANCC_RS13325	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ANCC_RS13330	COG0159	tryptophan synthase activity
ANCC_RS13335	COG0133	tryptophan synthase activity
ANCC_RS13340	COG0135	phosphoribosylanthranilate isomerase activity
ANCC_RS13345	COG0134	indole-3-glycerol-phosphate synthase activity
ANCC_RS13350	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ANCC_RS13350	COG0512	Glutamine amidotransferase of anthranilate synthase
ANCC_RS13375	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ANCC_RS13375	COG0493	'glutamate synthase
ANCC_RS13400	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ANCC_RS13415	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ANCC_RS13430	COG0427	acetyl-CoA hydrolase
ANCC_RS13435	COG1454	alcohol dehydrogenase
ANCC_RS13440	COG2030	dehydratase
ANCC_RS13455	COG1735	metal-dependent hydrolase with the TIM-barrel fold
ANCC_RS13460	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ANCC_RS13470	COG3775	system Galactitol-specific IIC component
ANCC_RS13485	COG3711	transcriptional antiterminator
ANCC_RS13485	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANCC_RS13495	COG1063	alcohol dehydrogenase
ANCC_RS13515	COG0463	Glycosyl transferase, family 2
ANCC_RS13515	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ANCC_RS13520	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ANCC_RS13530	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ANCC_RS13535	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ANCC_RS13540	COG0463	Glycosyl transferase, family 2
ANCC_RS13540	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
ANCC_RS13575	COG0463	Glycosyl transferase, family 2
ANCC_RS13585	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ANCC_RS13590	COG1028	Short-chain dehydrogenase reductase Sdr
ANCC_RS13595	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
ANCC_RS13625	COG0110	maltose O-acetyltransferase activity
ANCC_RS13635	COG3754	Rhamnan synthesis protein F
ANCC_RS13640	COG0438	transferase activity, transferring glycosyl groups
ANCC_RS13650	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ANCC_RS13675	COG2246	polysaccharide biosynthetic process
ANCC_RS13685	COG0463	Glycosyl transferase, family 2
ANCC_RS13695	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
ANCC_RS13725	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ANCC_RS13730	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ANCC_RS13750	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ANCC_RS13760	COG1126	abc transporter atp-binding protein
ANCC_RS13765	COG0765	amino acid transport
ANCC_RS13770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ANCC_RS13785	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ANCC_RS13795	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ANCC_RS13805	COG0587	DNA-directed DNA polymerase activity
ANCC_RS13815	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ANCC_RS13830	COG0733	neurotransmitter:sodium symporter activity
ANCC_RS13835	COG2205	protein histidine kinase activity
ANCC_RS13840	COG0745	RESPONSE REGULATOR receiver
ANCC_RS13900	COG3299	homolog of phage Mu protein gp47
ANCC_RS14015	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANCC_RS14020	COG1481	regulation of sporulation
ANCC_RS14025	COG1660	Displays ATPase and GTPase activities
ANCC_RS14030	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ANCC_RS14035	COG1940	carbohydrate kinase activity
ANCC_RS14040	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
ANCC_RS14045	COG0322	excinuclease ABC activity
ANCC_RS14060	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ANCC_RS14125	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ANCC_RS14130	COG0733	neurotransmitter:sodium symporter activity
ANCC_RS14135	COG2188	Transcriptional regulator
ANCC_RS14140	COG3437	response regulator, receiver
ANCC_RS14145	COG0784	Response regulator, receiver
ANCC_RS14145	COG2205	protein histidine kinase activity
ANCC_RS14145	COG5002	protein histidine kinase activity
ANCC_RS14150	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ANCC_RS14155	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ANCC_RS14160	COG1882	Formate acetyltransferase
ANCC_RS14165	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ANCC_RS14170	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ANCC_RS14175	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANCC_RS14175	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANCC_RS14175	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ANCC_RS14180	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ANCC_RS14185	COG3711	transcriptional antiterminator
ANCC_RS14185	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANCC_RS14190	COG0157	Belongs to the NadC ModD family
ANCC_RS14195	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ANCC_RS14200	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ANCC_RS14220	COG1070	Carbohydrate kinase
ANCC_RS14225	COG1063	alcohol dehydrogenase
ANCC_RS14230	COG3716	PTS system mannose fructose sorbose family IID component
ANCC_RS14240	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANCC_RS14240	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ANCC_RS14245	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANCC_RS14270	COG0191	fructose-bisphosphate aldolase activity
ANCC_RS14280	COG3775	system Galactitol-specific IIC component
ANCC_RS14285	COG3414	Phosphotransferase system galactitol-specific IIB component
ANCC_RS14295	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANCC_RS14300	COG3711	transcriptional antiterminator
ANCC_RS14300	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANCC_RS14340	COG3646	Phage regulatory protein
ANCC_RS14515	COG0740	serine-type endopeptidase activity
ANCC_RS14525	COG1802	Transcriptional regulator
ANCC_RS14525	COG4626	Terminase
ANCC_RS14550	COG0270	DNA (cytosine-5-)-methyltransferase activity
ANCC_RS14555	COG1475	DNA binding
ANCC_RS14745	COG3728	DNA packaging
ANCC_RS14745	COG5484	DNA packaging
ANCC_RS14895	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ANCC_RS14930	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ANCC_RS14935	COG1283	sodium-dependent phosphate transmembrane transporter activity
ANCC_RS14940	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ANCC_RS14940	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANCC_RS14940	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ANCC_RS14945	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ANCC_RS14950	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ANCC_RS14950	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANCC_RS14950	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ANCC_RS14970	COG2376	Dihydroxyacetone kinase
ANCC_RS14975	COG2376	Dihydroxyacetone kinase
ANCC_RS14990	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ANCC_RS14995	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ANCC_RS15000	COG0561	phosphatase activity
ANCC_RS15010	COG1309	transcriptional regulator
ANCC_RS15015	COG2814	Major facilitator Superfamily
ANCC_RS15020	COG1489	DNA binding
ANCC_RS15030	COG1116	anion transmembrane transporter activity
ANCC_RS15035	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ANCC_RS15040	COG5001	Diguanylate cyclase
ANCC_RS15050	COG0613	PHP domain protein
ANCC_RS15085	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ANCC_RS15090	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
ANCC_RS15100	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANCC_RS15105	COG3711	transcriptional antiterminator
ANCC_RS15115	COG1349	DNA-binding transcription factor activity
ANCC_RS15120	COG1063	alcohol dehydrogenase
ANCC_RS15130	COG2213	PTS system mannitol-specific
ANCC_RS15130	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANCC_RS15140	COG1063	alcohol dehydrogenase
ANCC_RS15150	COG0504	CTP synthase activity
ANCC_RS15170	COG2376	Dihydroxyacetone kinase
ANCC_RS15180	COG0698	ribose 5-phosphate isomerase
ANCC_RS15185	COG0546	phosphoglycolate phosphatase activity
ANCC_RS15195	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ANCC_RS15200	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ANCC_RS15205	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANCC_RS15205	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ANCC_RS15205	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ANCC_RS15220	COG0741	lytic transglycosylase activity
ANCC_RS15220	COG0791	NLP P60 protein
ANCC_RS15230	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ANCC_RS15240	COG2199	diguanylate cyclase activity
ANCC_RS15245	COG1028	Short-chain dehydrogenase reductase Sdr
ANCC_RS15265	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ANCC_RS15270	COG0741	lytic transglycosylase activity
ANCC_RS15270	COG0791	NLP P60 protein
ANCC_RS15350	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ANCC_RS15360	COG1234	tRNA 3'-trailer cleavage
ANCC_RS15365	COG0456	acetyltransferase
ANCC_RS15370	COG1214	PFAM Peptidase M22, glycoprotease
ANCC_RS15375	COG0802	atpase or kinase
ANCC_RS15385	COG2002	toxin-antitoxin pair type II binding
ANCC_RS15400	COG4999	Histidine kinase
ANCC_RS15400	COG2205	protein histidine kinase activity
ANCC_RS15400	COG3437	response regulator, receiver
ANCC_RS15400	COG3850	Histidine kinase
ANCC_RS15425	COG0793	Belongs to the peptidase S41A family
ANCC_RS15425	COG3409	Peptidoglycan-binding domain 1 protein
ANCC_RS15430	COG2610	gluconate transmembrane transporter activity
ANCC_RS15440	COG2030	dehydratase
ANCC_RS15445	COG0583	DNA-binding transcription factor activity
ANCC_RS15450	COG0739	heme binding
ANCC_RS15455	COG2177	Part of the ABC transporter FtsEX involved in
ANCC_RS15460	COG2884	Cell division ATP-binding protein ftsE
ANCC_RS15465	COG3835	regulator
ANCC_RS15470	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ANCC_RS15480	COG0300	oxidoreductase activity
ANCC_RS15485	COG2183	response to ionizing radiation
ANCC_RS15500	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
ANCC_RS15505	COG0460	homoserine dehydrogenase
ANCC_RS15510	COG4492	Belongs to the UPF0735 family
ANCC_RS15520	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ANCC_RS15525	COG0653	protein targeting
ANCC_RS15530	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ANCC_RS15535	COG0492	ferredoxin-NADP+ reductase activity
ANCC_RS15545	COG0697	spore germination
ANCC_RS15550	COG1917	Cupin 2, conserved barrel domain protein
ANCC_RS15550	COG2207	Transcriptional regulator
ANCC_RS15555	COG0640	Transcriptional regulator
ANCC_RS15565	COG2252	PERMEase
ANCC_RS15570	COG0488	(ABC) transporter
ANCC_RS15580	COG1285	pathogenesis
ANCC_RS15585	COG0110	maltose O-acetyltransferase activity
ANCC_RS15590	COG1193	negative regulation of DNA recombination
ANCC_RS15600	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ANCC_RS15600	COG1263	PTS System
ANCC_RS15600	COG2190	(PTS) system
ANCC_RS15610	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ANCC_RS15610	COG2190	(PTS) system
ANCC_RS15610	COG1263	PTS System
ANCC_RS15615	COG2378	regulation of single-species biofilm formation
ANCC_RS15630	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ANCC_RS15635	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ANCC_RS15635	COG1328	CTP reductase activity
ANCC_RS15645	COG0101	tRNA pseudouridine synthase activity
ANCC_RS15650	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ANCC_RS15655	COG1122	ATPase activity
ANCC_RS15660	COG1122	ATPase activity
ANCC_RS15670	COG0203	ribosomal protein L17
ANCC_RS15675	COG0202	RNA polymerase activity
ANCC_RS15680	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ANCC_RS15685	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ANCC_RS15695	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ANCC_RS15700	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ANCC_RS15725	COG1841	ribosomal large subunit assembly
ANCC_RS15740	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ANCC_RS15745	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ANCC_RS15750	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ANCC_RS15755	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ANCC_RS15760	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ANCC_RS15765	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ANCC_RS15770	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ANCC_RS15775	COG0255	Belongs to the universal ribosomal protein uL29 family
ANCC_RS15780	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ANCC_RS15790	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ANCC_RS15800	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ANCC_RS15815	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ANCC_RS15820	COG0051	transcription antitermination factor activity, RNA binding
ANCC_RS15835	COG0656	L-ascorbic acid biosynthetic process
ANCC_RS15845	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
ANCC_RS15850	COG2376	Dihydroxyacetone kinase
ANCC_RS15855	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ANCC_RS15860	COG1349	DNA-binding transcription factor activity
ANCC_RS15870	COG0825	malonyl-CoA metabolic process
ANCC_RS15880	COG0439	Biotin carboxylase
ANCC_RS15890	COG0511	ligase activity, forming carbon-carbon bonds
ANCC_RS15895	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ANCC_RS15900	COG1028	Short-chain dehydrogenase reductase Sdr
ANCC_RS15905	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ANCC_RS15910	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ANCC_RS15915	COG1063	alcohol dehydrogenase
ANCC_RS15920	COG1131	(ABC) transporter
ANCC_RS15940	COG1592	Rubrerythrin
ANCC_RS15940	COG1773	rubredoxin
ANCC_RS15950	COG0513	Belongs to the DEAD box helicase family
ANCC_RS15960	COG1342	Belongs to the UPF0251 family
ANCC_RS15985	COG2827	Endonuclease containing a URI domain
ANCC_RS15995	COG2385	sporulation resulting in formation of a cellular spore
ANCC_RS16000	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ANCC_RS16010	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ANCC_RS16015	COG3716	PTS system mannose fructose sorbose family IID component
ANCC_RS16020	COG3715	PTS system
ANCC_RS16035	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
ANCC_RS16035	COG3933	PFAM sigma-54 factor interaction domain-containing protein
ANCC_RS16040	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANCC_RS16045	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ANCC_RS16050	COG0204	Acyl-transferase
ANCC_RS16060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ANCC_RS16075	COG0564	pseudouridine synthase activity
ANCC_RS16080	COG0745	RESPONSE REGULATOR receiver
ANCC_RS16085	COG5002	protein histidine kinase activity
ANCC_RS16090	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ANCC_RS16095	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ANCC_RS16100	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ANCC_RS16105	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ANCC_RS16140	COG0488	(ABC) transporter
ANCC_RS16145	COG1349	DNA-binding transcription factor activity
ANCC_RS16155	COG1737	Transcriptional regulator
ANCC_RS16160	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ANCC_RS16160	COG2190	(PTS) system
ANCC_RS16160	COG1263	PTS System
ANCC_RS16165	COG1486	melibiose metabolic process
ANCC_RS16185	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ANCC_RS16185	COG1263	PTS System
ANCC_RS16190	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ANCC_RS16195	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ANCC_RS16200	COG2207	Transcriptional regulator
ANCC_RS16200	COG3708	Transcriptional regulator
ANCC_RS16205	COG0860	N-Acetylmuramoyl-L-alanine amidase
ANCC_RS16205	COG1388	LysM domain
ANCC_RS16210	COG0726	polysaccharide deacetylase
ANCC_RS16215	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ANCC_RS16220	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ANCC_RS16230	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ANCC_RS16235	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ANCC_RS16245	COG0537	adenosine 5'-monophosphoramidase activity
ANCC_RS16250	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ANCC_RS16255	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ANCC_RS16260	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ANCC_RS16265	COG3290	protein histidine kinase activity
ANCC_RS16270	COG0705	Rhomboid family
ANCC_RS16270	COG0457	Tetratricopeptide repeat
ANCC_RS16325	COG0159	tryptophan synthase activity
ANCC_RS16340	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANCC_RS16350	COG4086	secreted protein
ANCC_RS16365	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ANCC_RS16380	COG0765	amino acid transport
ANCC_RS16385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ANCC_RS16390	COG1464	Belongs to the NlpA lipoprotein family
ANCC_RS16395	COG1194	a g-specific adenine glycosylase
ANCC_RS16400	COG1040	competence protein
ANCC_RS16430	COG3732	PTS system glucitol sorbitol-specific
ANCC_RS16435	COG3730	PTS system glucitol sorbitol-specific
ANCC_RS16460	COG3732	PTS system glucitol sorbitol-specific
ANCC_RS16465	COG3730	PTS system glucitol sorbitol-specific
ANCC_RS16490	COG1349	DNA-binding transcription factor activity
ANCC_RS16495	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANCC_RS16495	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ANCC_RS16500	COG3715	PTS system
ANCC_RS16510	COG1349	DNA-binding transcription factor activity
ANCC_RS16515	COG0686	Belongs to the AlaDH PNT family
ANCC_RS16535	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ANCC_RS16545	COG0116	Belongs to the methyltransferase superfamily
ANCC_RS16545	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ANCC_RS16555	COG0726	polysaccharide deacetylase
ANCC_RS16570	COG0726	polysaccharide deacetylase
ANCC_RS16575	COG2205	protein histidine kinase activity
ANCC_RS16575	COG4999	Histidine kinase
ANCC_RS16575	COG3437	response regulator, receiver
ANCC_RS16575	COG3850	Histidine kinase
ANCC_RS16590	COG3437	response regulator, receiver
ANCC_RS16610	COG4886	Leucine-rich repeat (LRR) protein
ANCC_RS16620	COG4555	ABC transporter
ANCC_RS16635	COG4886	Leucine-rich repeat (LRR) protein
ANCC_RS16650	COG1704	LemA family
ANCC_RS16660	COG1592	Rubrerythrin
ANCC_RS16660	COG1773	rubredoxin
ANCC_RS16685	COG1253	flavin adenine dinucleotide binding
ANCC_RS16700	COG1607	acyl-coa hydrolase
ANCC_RS16710	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ANCC_RS16720	COG2086	electron transfer activity
ANCC_RS16725	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ANCC_RS16730	COG1960	acyl-CoA dehydrogenase activity
ANCC_RS16750	COG4978	Transcriptional regulator
ANCC_RS16750	COG0789	Transcriptional regulator
ANCC_RS16780	COG0167	dihydroorotate dehydrogenase activity
ANCC_RS16780	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ANCC_RS16785	COG0493	'glutamate synthase
ANCC_RS16810	COG3842	ATPase activity
ANCC_RS16820	COG2723	6-phospho-beta-galactosidase activity
ANCC_RS16825	COG2190	(PTS) system
ANCC_RS16825	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ANCC_RS16825	COG1263	PTS System
ANCC_RS16830	COG3711	transcriptional antiterminator
ANCC_RS16835	COG1959	2 iron, 2 sulfur cluster binding
ANCC_RS16885	COG1979	alcohol dehydrogenase
ANCC_RS16890	COG3716	PTS system mannose fructose sorbose family IID component
ANCC_RS16900	COG1063	alcohol dehydrogenase
ANCC_RS16905	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ANCC_RS16915	COG0534	Mate efflux family protein
ANCC_RS16920	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ANCC_RS16925	COG3716	PTS system mannose fructose sorbose family IID component
ANCC_RS16930	COG3715	PTS system
ANCC_RS16950	COG2222	sugar isomerase
ANCC_RS16955	COG2188	Transcriptional regulator
ANCC_RS16975	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ANCC_RS16980	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ANCC_RS16985	COG0049	tRNA binding
ANCC_RS16990	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ANCC_RS16995	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ANCC_RS17000	COG0085	RNA polymerase activity
ANCC_RS17005	COG0222	ribosome binding
ANCC_RS17025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ANCC_RS17030	COG1126	abc transporter atp-binding protein
ANCC_RS17035	COG0765	amino acid transport
ANCC_RS17040	COG0765	amino acid transport
ANCC_RS17080	COG2226	methyltransferase
ANCC_RS17090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ANCC_RS17145	COG3279	Response regulator of the LytR AlgR family
ANCC_RS17160	COG0081	regulation of translation
ANCC_RS17170	COG0250	Participates in transcription elongation, termination and antitermination
ANCC_RS17180	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ANCC_RS17185	COG0602	queuosine metabolic process
ANCC_RS17195	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ANCC_RS17210	COG0697	spore germination
ANCC_RS17215	COG1802	Transcriptional regulator
ANCC_RS17220	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ANCC_RS17230	COG4466	Protein conserved in bacteria
ANCC_RS17235	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ANCC_RS17250	COG1592	Rubrerythrin
ANCC_RS17270	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ANCC_RS17280	COG0756	dUTP diphosphatase activity
ANCC_RS17285	COG0166	Belongs to the GPI family
ANCC_RS17290	COG0726	polysaccharide deacetylase
ANCC_RS17300	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ANCC_RS17310	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ANCC_RS17340	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ANCC_RS17360	COG0371	Dehydrogenase
ANCC_RS17365	COG3775	system Galactitol-specific IIC component
ANCC_RS17375	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANCC_RS17375	COG2213	PTS system mannitol-specific
ANCC_RS17380	COG3711	transcriptional antiterminator
ANCC_RS17380	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANCC_RS17385	COG1105	Belongs to the carbohydrate kinase PfkB family
ANCC_RS17390	COG1349	DNA-binding transcription factor activity
ANCC_RS17400	COG1136	(ABC) transporter
ANCC_RS17415	COG2205	protein histidine kinase activity
ANCC_RS17420	COG0745	RESPONSE REGULATOR receiver
ANCC_RS17425	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ANCC_RS17435	COG1475	DNA binding
ANCC_RS17440	COG1192	Involved in chromosome partitioning
ANCC_RS17445	COG0018	arginyl-trna synthetase
ANCC_RS17460	COG0357	Ribosomal RNA small subunit methyltransferase G
ANCC_RS17465	COG0445	tRNA wobble uridine modification
ANCC_RS17470	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ANCC_RS17475	COG1847	R3H domain protein
ANCC_RS17480	COG0706	membrane insertase activity
ANCC_RS17485	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ANCC_RS17490	COG0594	ribonuclease P activity
ANCC_RS17495	COG0230	Belongs to the bacterial ribosomal protein bL34 family