locus-tag	class	description
LCQ53_RS00015	COG0799	negative regulation of ribosome biogenesis
LCQ53_RS00020	COG1713	HD superfamily hydrolase involved in NAD metabolism
LCQ53_RS00025	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LCQ53_RS00030	COG1534	Rna-binding protein
LCQ53_RS00035	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LCQ53_RS00040	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LCQ53_RS00055	COG1530	ribonuclease E activity
LCQ53_RS00060	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LCQ53_RS00085	COG0784	Response regulator, receiver
LCQ53_RS00085	COG2198	Histidine kinase
LCQ53_RS00085	COG2205	protein histidine kinase activity
LCQ53_RS00105	COG0714	Associated with various cellular activities
LCQ53_RS00110	COG1757	Na H antiporter
LCQ53_RS00115	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LCQ53_RS00125	COG0352	thiamine-phosphate diphosphorylase activity
LCQ53_RS00125	COG0351	phosphomethylpyrimidine kinase
LCQ53_RS00135	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
LCQ53_RS00170	COG1136	(ABC) transporter
LCQ53_RS00215	COG0583	DNA-binding transcription factor activity
LCQ53_RS00220	COG1979	alcohol dehydrogenase
LCQ53_RS00225	COG0667	Aldo Keto reductase
LCQ53_RS00255	COG2207	Transcriptional regulator
LCQ53_RS00255	COG3708	Transcriptional regulator
LCQ53_RS00265	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LCQ53_RS00320	COG0561	phosphatase activity
LCQ53_RS00325	COG0495	leucyl-tRNA aminoacylation
LCQ53_RS00330	COG1376	ErfK ybiS ycfS ynhG family protein
LCQ53_RS00340	COG1362	aminopeptidase activity
LCQ53_RS00345	COG1393	Belongs to the ArsC family
LCQ53_RS00350	COG1686	Belongs to the peptidase S11 family
LCQ53_RS00355	COG2199	diguanylate cyclase activity
LCQ53_RS00360	COG3300	MHYT domain
LCQ53_RS00360	COG5001	Diguanylate cyclase
LCQ53_RS00365	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
LCQ53_RS00375	COG0427	acetyl-CoA hydrolase
LCQ53_RS00380	COG0039	L-malate dehydrogenase activity
LCQ53_RS00415	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
LCQ53_RS00420	COG5001	Diguanylate cyclase
LCQ53_RS00420	COG3300	MHYT domain
LCQ53_RS00425	COG5001	Diguanylate cyclase
LCQ53_RS00425	COG3300	MHYT domain
LCQ53_RS00435	COG2199	diguanylate cyclase activity
LCQ53_RS00440	COG0739	heme binding
LCQ53_RS00460	COG2203	Gaf domain
LCQ53_RS00460	COG4251	negative regulation of phosphorylation
LCQ53_RS00460	COG3706	GGDEF domain
LCQ53_RS00460	COG5001	Diguanylate cyclase
LCQ53_RS00475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LCQ53_RS00490	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LCQ53_RS00500	COG3620	sequence-specific DNA binding
LCQ53_RS00510	COG2086	electron transfer activity
LCQ53_RS00515	COG1960	acyl-CoA dehydrogenase activity
LCQ53_RS00520	COG1250	3-hydroxyacyl-CoA dehydrogenase
LCQ53_RS00525	COG1024	Enoyl-CoA hydratase
LCQ53_RS00530	COG0183	Belongs to the thiolase family
LCQ53_RS00540	COG0071	Belongs to the small heat shock protein (HSP20) family
LCQ53_RS00545	COG0440	acetolactate synthase activity
LCQ53_RS00550	COG0028	Belongs to the TPP enzyme family
LCQ53_RS00555	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LCQ53_RS00565	COG1408	metallophosphoesterase
LCQ53_RS00575	COG3732	PTS system glucitol sorbitol-specific
LCQ53_RS00580	COG3730	PTS system glucitol sorbitol-specific
LCQ53_RS00590	COG3711	transcriptional antiterminator
LCQ53_RS00590	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCQ53_RS00600	COG1686	Belongs to the peptidase S11 family
LCQ53_RS00610	COG0768	penicillin binding
LCQ53_RS00620	COG0826	peptidase U32
LCQ53_RS00630	COG2255	four-way junction helicase activity
LCQ53_RS00635	COG0632	four-way junction helicase activity
LCQ53_RS00650	COG1346	cytolysis
LCQ53_RS00655	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LCQ53_RS00670	COG2002	toxin-antitoxin pair type II binding
LCQ53_RS00690	COG2873	o-acetylhomoserine
LCQ53_RS00700	COG4120	Belongs to the binding-protein-dependent transport system permease family
LCQ53_RS00715	COG1185	polyribonucleotide nucleotidyltransferase activity
LCQ53_RS00720	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LCQ53_RS00725	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LCQ53_RS00730	COG0564	pseudouridine synthase activity
LCQ53_RS00735	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LCQ53_RS00740	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LCQ53_RS00755	COG1799	cell septum assembly
LCQ53_RS00760	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LCQ53_RS00770	COG1242	4 iron, 4 sulfur cluster binding
LCQ53_RS00775	COG1686	Belongs to the peptidase S11 family
LCQ53_RS00780	COG1803	Methylglyoxal synthase
LCQ53_RS00785	COG0772	Belongs to the SEDS family
LCQ53_RS00790	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
LCQ53_RS00795	COG2894	cell division
LCQ53_RS00800	COG0850	regulation of cytokinetic process
LCQ53_RS00805	COG0768	penicillin binding
LCQ53_RS00820	COG1077	Cell shape determining protein MreB Mrl
LCQ53_RS00825	COG2003	Belongs to the UPF0758 family
LCQ53_RS00830	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
LCQ53_RS00835	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LCQ53_RS00840	COG0295	cytidine deaminase activity
LCQ53_RS00850	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LCQ53_RS00855	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LCQ53_RS00860	COG0562	UDP-galactopyranose mutase
LCQ53_RS00865	COG1283	sodium-dependent phosphate transmembrane transporter activity
LCQ53_RS00875	COG0058	SHG alpha-glucan phosphorylase activity
LCQ53_RS00880	COG0297	glycogen (starch) synthase activity
LCQ53_RS00885	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LCQ53_RS00890	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LCQ53_RS00900	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LCQ53_RS00905	COG0552	protein localization to endoplasmic reticulum
LCQ53_RS00910	COG1196	nuclear chromosome segregation
LCQ53_RS00915	COG0571	ribonuclease III activity
LCQ53_RS00920	COG0416	fatty acid biosynthetic process
LCQ53_RS00925	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LCQ53_RS00935	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LCQ53_RS00940	COG0280	phosphate acetyltransferase
LCQ53_RS00945	COG1323	Belongs to the UPF0348 family
LCQ53_RS00950	COG3314	Sporulation integral membrane protein YlbJ
LCQ53_RS00960	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LCQ53_RS00965	COG0742	ribosomal rna small subunit methyltransferase
LCQ53_RS00975	COG1254	Belongs to the acylphosphatase family
LCQ53_RS00980	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LCQ53_RS00985	COG1461	Dihydroxyacetone kinase
LCQ53_RS00995	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LCQ53_RS01045	COG0583	DNA-binding transcription factor activity
LCQ53_RS01055	COG1725	Transcriptional regulator
LCQ53_RS01060	COG1131	(ABC) transporter
LCQ53_RS01075	COG0107	imidazoleglycerol-phosphate synthase activity
LCQ53_RS01080	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LCQ53_RS01090	COG5002	protein histidine kinase activity
LCQ53_RS01095	COG0745	RESPONSE REGULATOR receiver
LCQ53_RS01105	COG0561	phosphatase activity
LCQ53_RS01115	COG0482	sulfurtransferase activity
LCQ53_RS01120	COG0822	iron-sulfur transferase activity
LCQ53_RS01130	COG1959	2 iron, 2 sulfur cluster binding
LCQ53_RS01135	COG2244	polysaccharide biosynthetic process
LCQ53_RS01140	COG1079	Belongs to the binding-protein-dependent transport system permease family
LCQ53_RS01145	COG4603	Belongs to the binding-protein-dependent transport system permease family
LCQ53_RS01150	COG3845	ABC transporter
LCQ53_RS01185	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LCQ53_RS01190	COG1595	DNA-templated transcription, initiation
LCQ53_RS01195	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LCQ53_RS01205	COG0215	cysteine-tRNA ligase activity
LCQ53_RS01210	COG1045	serine acetyltransferase
LCQ53_RS01225	COG1268	BioY protein
LCQ53_RS01230	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LCQ53_RS01245	COG0784	Response regulator, receiver
LCQ53_RS01245	COG2198	Histidine kinase
LCQ53_RS01245	COG2205	protein histidine kinase activity
LCQ53_RS01250	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LCQ53_RS01255	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LCQ53_RS01260	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LCQ53_RS01265	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LCQ53_RS01270	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LCQ53_RS01275	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LCQ53_RS01280	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LCQ53_RS01290	COG0356	it plays a direct role in the translocation of protons across the membrane
LCQ53_RS01335	COG0210	DNA helicase
LCQ53_RS01345	COG4496	protein, YerC YecD
LCQ53_RS01350	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LCQ53_RS01365	COG1131	(ABC) transporter
LCQ53_RS01370	COG4585	Histidine kinase
LCQ53_RS01375	COG2197	response regulator
LCQ53_RS01380	COG4536	flavin adenine dinucleotide binding
LCQ53_RS01390	COG0210	DNA helicase
LCQ53_RS01395	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LCQ53_RS01400	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LCQ53_RS01430	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCQ53_RS01435	COG3711	transcriptional antiterminator
LCQ53_RS01440	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LCQ53_RS01465	COG1737	Transcriptional regulator
LCQ53_RS01485	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCQ53_RS01485	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCQ53_RS01490	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCQ53_RS01500	COG0534	Mate efflux family protein
LCQ53_RS01510	COG0725	ABC transporter, periplasmic molybdate-binding protein
LCQ53_RS01515	COG4149	molybdate abc transporter
LCQ53_RS01525	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LCQ53_RS01530	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
LCQ53_RS01530	COG3608	succinylglutamate desuccinylase aspartoacylase
LCQ53_RS01545	COG1131	(ABC) transporter
LCQ53_RS01550	COG1309	transcriptional regulator
LCQ53_RS01555	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LCQ53_RS01570	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LCQ53_RS01580	COG1131	(ABC) transporter
LCQ53_RS01605	COG3300	MHYT domain
LCQ53_RS01605	COG5001	Diguanylate cyclase
LCQ53_RS01620	COG0521	Mo-molybdopterin cofactor biosynthetic process
LCQ53_RS01640	COG3608	succinylglutamate desuccinylase aspartoacylase
LCQ53_RS01640	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
LCQ53_RS01660	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LCQ53_RS01660	COG0493	'glutamate synthase
LCQ53_RS01665	COG0402	S-adenosylhomocysteine deaminase activity
LCQ53_RS01680	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LCQ53_RS01685	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LCQ53_RS01690	COG0549	Belongs to the carbamate kinase family
LCQ53_RS01730	COG3620	sequence-specific DNA binding
LCQ53_RS01740	COG0791	NLP P60 protein
LCQ53_RS01740	COG3883	PFAM NLP P60 protein
LCQ53_RS01760	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LCQ53_RS01780	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCQ53_RS01780	COG3711	transcriptional antiterminator
LCQ53_RS01785	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LCQ53_RS01795	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LCQ53_RS01800	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LCQ53_RS01825	COG2378	regulation of single-species biofilm formation
LCQ53_RS01835	COG0546	phosphoglycolate phosphatase activity
LCQ53_RS01840	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
LCQ53_RS01845	COG1105	Belongs to the carbohydrate kinase PfkB family
LCQ53_RS01850	COG1063	alcohol dehydrogenase
LCQ53_RS01860	COG3775	system Galactitol-specific IIC component
LCQ53_RS01865	COG3414	Phosphotransferase system galactitol-specific IIB component
LCQ53_RS01875	COG3711	transcriptional antiterminator
LCQ53_RS01875	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCQ53_RS01885	COG0577	efflux transmembrane transporter activity
LCQ53_RS01890	COG0577	efflux transmembrane transporter activity
LCQ53_RS01890	COG1136	(ABC) transporter
LCQ53_RS01900	COG1242	4 iron, 4 sulfur cluster binding
LCQ53_RS01915	COG0371	Dehydrogenase
LCQ53_RS01925	COG0371	Dehydrogenase
LCQ53_RS01930	COG0698	ribose 5-phosphate isomerase
LCQ53_RS01935	COG3732	PTS system glucitol sorbitol-specific
LCQ53_RS01940	COG3730	PTS system glucitol sorbitol-specific
LCQ53_RS01955	COG0561	phosphatase activity
LCQ53_RS01965	COG0154	amidase activity
LCQ53_RS01970	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LCQ53_RS02000	COG0515	serine threonine protein kinase
LCQ53_RS02000	COG2815	serine threonine protein kinase
LCQ53_RS02005	COG0631	protein serine/threonine phosphatase activity
LCQ53_RS02010	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LCQ53_RS02015	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LCQ53_RS02015	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LCQ53_RS02020	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LCQ53_RS02025	COG0242	peptide deformylase activity
LCQ53_RS02030	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LCQ53_RS02035	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LCQ53_RS02040	COG0735	belongs to the Fur family
LCQ53_RS02045	COG0232	Belongs to the dGTPase family. Type 2 subfamily
LCQ53_RS02050	COG0688	phosphatidylethanolamine metabolic process
LCQ53_RS02055	COG1183	phosphatidylcholine synthase activity
LCQ53_RS02070	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LCQ53_RS02080	COG0517	IMP dehydrogenase activity
LCQ53_RS02080	COG0516	GMP reductase activity
LCQ53_RS02090	COG0493	'glutamate synthase
LCQ53_RS02090	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
LCQ53_RS02105	COG0459	protein refolding
LCQ53_RS02110	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LCQ53_RS02115	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LCQ53_RS02120	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LCQ53_RS02125	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LCQ53_RS02135	COG0542	response to heat
LCQ53_RS02145	COG0151	Belongs to the GarS family
LCQ53_RS02150	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LCQ53_RS02155	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LCQ53_RS02165	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LCQ53_RS02190	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LCQ53_RS02200	COG0167	dihydroorotate dehydrogenase activity
LCQ53_RS02205	COG0543	2 iron, 2 sulfur cluster binding
LCQ53_RS02210	COG0284	orotidine-5'-phosphate decarboxylase activity
LCQ53_RS02215	COG5002	protein histidine kinase activity
LCQ53_RS02225	COG0704	Plays a role in the regulation of phosphate uptake
LCQ53_RS02230	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LCQ53_RS02235	COG0581	inorganic phosphate transmembrane transporter activity
LCQ53_RS02240	COG0573	inorganic phosphate transmembrane transporter activity
LCQ53_RS02255	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LCQ53_RS02265	COG3290	protein histidine kinase activity
LCQ53_RS02265	COG3829	transcription factor binding
LCQ53_RS02295	COG0423	glycine-tRNA ligase activity
LCQ53_RS02300	COG1381	Involved in DNA repair and RecF pathway recombination
LCQ53_RS02305	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LCQ53_RS02330	COG0789	Transcriptional regulator
LCQ53_RS02360	COG3757	hydrolase, family 25
LCQ53_RS02365	COG1191	sigma factor activity
LCQ53_RS02375	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LCQ53_RS02385	COG0772	Belongs to the SEDS family
LCQ53_RS02390	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LCQ53_RS02400	COG0768	penicillin binding
LCQ53_RS02405	COG0768	penicillin binding
LCQ53_RS02415	COG0275	rRNA processing
LCQ53_RS02420	COG2001	Belongs to the MraZ family
LCQ53_RS02425	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LCQ53_RS02430	COG0012	GTP binding
LCQ53_RS02435	COG0791	NLP P60 protein
LCQ53_RS02440	COG0436	Aminotransferase
LCQ53_RS02455	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LCQ53_RS02470	COG0393	Putative heavy-metal-binding
LCQ53_RS02575	COG3299	homolog of phage Mu protein gp47
LCQ53_RS02580	COG3628	GPW Gp25 family protein
LCQ53_RS02825	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LCQ53_RS02830	COG1518	maintenance of DNA repeat elements
LCQ53_RS02870	COG0275	rRNA processing
LCQ53_RS02880	COG0789	Transcriptional regulator
LCQ53_RS02880	COG4978	Transcriptional regulator
LCQ53_RS02895	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LCQ53_RS02920	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LCQ53_RS02925	COG0436	Aminotransferase
LCQ53_RS02930	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LCQ53_RS02935	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LCQ53_RS02940	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
LCQ53_RS02950	COG1217	gtp-binding protein TYPA
LCQ53_RS02960	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LCQ53_RS02985	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
LCQ53_RS02990	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LCQ53_RS02995	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LCQ53_RS03005	COG0673	inositol 2-dehydrogenase activity
LCQ53_RS03010	COG1132	(ABC) transporter
LCQ53_RS03020	COG1846	Transcriptional regulator
LCQ53_RS03040	COG0653	protein targeting
LCQ53_RS03045	COG0640	Transcriptional regulator
LCQ53_RS03050	COG0701	Predicted permease
LCQ53_RS03055	COG2365	Tyrosine phosphatase family
LCQ53_RS03065	COG0656	L-ascorbic acid biosynthetic process
LCQ53_RS03070	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LCQ53_RS03080	COG1609	Transcriptional regulator
LCQ53_RS03085	COG1686	Belongs to the peptidase S11 family
LCQ53_RS03095	COG0523	cobalamin synthesis protein
LCQ53_RS03115	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LCQ53_RS03120	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
LCQ53_RS03125	COG2080	2 iron, 2 sulfur cluster binding
LCQ53_RS03145	COG1349	DNA-binding transcription factor activity
LCQ53_RS03150	COG2213	PTS system mannitol-specific
LCQ53_RS03150	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCQ53_RS03155	COG0673	inositol 2-dehydrogenase activity
LCQ53_RS03160	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LCQ53_RS03175	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LCQ53_RS03180	COG2890	protein-(glutamine-N5) methyltransferase activity
LCQ53_RS03185	COG3872	metal-dependent enzyme
LCQ53_RS03190	COG0254	rRNA binding
LCQ53_RS03195	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LCQ53_RS03205	COG2172	sigma factor antagonist activity
LCQ53_RS03225	COG0285	dihydrofolate synthase activity
LCQ53_RS03230	COG0525	valine-tRNA ligase activity
LCQ53_RS03255	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LCQ53_RS03280	COG0372	Belongs to the citrate synthase family
LCQ53_RS03285	COG4598	ABC transporter
LCQ53_RS03295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LCQ53_RS03305	COG4193	domain, Protein
LCQ53_RS03335	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LCQ53_RS03340	COG0159	tryptophan synthase activity
LCQ53_RS03345	COG0133	tryptophan synthase activity
LCQ53_RS03350	COG0135	phosphoribosylanthranilate isomerase activity
LCQ53_RS03355	COG0134	indole-3-glycerol-phosphate synthase activity
LCQ53_RS03360	COG0512	Glutamine amidotransferase of anthranilate synthase
LCQ53_RS03360	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LCQ53_RS03385	COG0493	'glutamate synthase
LCQ53_RS03385	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LCQ53_RS03410	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LCQ53_RS03425	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LCQ53_RS03440	COG0427	acetyl-CoA hydrolase
LCQ53_RS03445	COG1454	alcohol dehydrogenase
LCQ53_RS03450	COG2030	dehydratase
LCQ53_RS03465	COG1735	metal-dependent hydrolase with the TIM-barrel fold
LCQ53_RS03470	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LCQ53_RS03480	COG3775	system Galactitol-specific IIC component
LCQ53_RS03495	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCQ53_RS03495	COG3711	transcriptional antiterminator
LCQ53_RS03505	COG1063	alcohol dehydrogenase
LCQ53_RS03520	COG0463	Glycosyl transferase, family 2
LCQ53_RS03520	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LCQ53_RS03530	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LCQ53_RS03535	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LCQ53_RS03560	COG2755	lipolytic protein G-D-S-L family
LCQ53_RS03575	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LCQ53_RS03600	COG1086	Polysaccharide biosynthesis protein
LCQ53_RS03625	COG0110	maltose O-acetyltransferase activity
LCQ53_RS03630	COG2030	dehydratase
LCQ53_RS03650	COG0367	asparagine synthase
LCQ53_RS03660	COG0728	peptidoglycan biosynthetic process
LCQ53_RS03680	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LCQ53_RS03685	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LCQ53_RS03705	COG2246	polysaccharide biosynthetic process
LCQ53_RS03715	COG0463	Glycosyl transferase, family 2
LCQ53_RS03725	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
LCQ53_RS03755	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LCQ53_RS03780	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LCQ53_RS03790	COG1126	abc transporter atp-binding protein
LCQ53_RS03795	COG0765	amino acid transport
LCQ53_RS03800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LCQ53_RS03815	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LCQ53_RS03825	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LCQ53_RS03835	COG0587	DNA-directed DNA polymerase activity
LCQ53_RS03845	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LCQ53_RS03860	COG0235	Class ii aldolase
LCQ53_RS03865	COG2376	Dihydroxyacetone kinase
LCQ53_RS03870	COG2376	Dihydroxyacetone kinase
LCQ53_RS03880	COG3775	system Galactitol-specific IIC component
LCQ53_RS03890	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCQ53_RS03895	COG1063	alcohol dehydrogenase
LCQ53_RS03905	COG0733	neurotransmitter:sodium symporter activity
LCQ53_RS03910	COG2205	protein histidine kinase activity
LCQ53_RS03915	COG0745	RESPONSE REGULATOR receiver
LCQ53_RS03965	COG3299	homolog of phage Mu protein gp47
LCQ53_RS03985	COG1652	LysM domain
LCQ53_RS04110	COG2207	Transcriptional regulator
LCQ53_RS04110	COG4753	response regulator
LCQ53_RS04135	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCQ53_RS04140	COG1481	regulation of sporulation
LCQ53_RS04145	COG1660	Displays ATPase and GTPase activities
LCQ53_RS04150	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LCQ53_RS04155	COG1940	carbohydrate kinase activity
LCQ53_RS04160	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LCQ53_RS04165	COG0322	excinuclease ABC activity
LCQ53_RS04180	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LCQ53_RS04250	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LCQ53_RS04255	COG0733	neurotransmitter:sodium symporter activity
LCQ53_RS04260	COG2188	Transcriptional regulator
LCQ53_RS04265	COG3437	response regulator, receiver
LCQ53_RS04270	COG5002	protein histidine kinase activity
LCQ53_RS04270	COG0784	Response regulator, receiver
LCQ53_RS04270	COG2205	protein histidine kinase activity
LCQ53_RS04275	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LCQ53_RS04280	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LCQ53_RS04285	COG1882	Formate acetyltransferase
LCQ53_RS04290	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LCQ53_RS04295	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LCQ53_RS04300	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCQ53_RS04300	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCQ53_RS04300	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LCQ53_RS04305	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LCQ53_RS04310	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCQ53_RS04310	COG3711	transcriptional antiterminator
LCQ53_RS04315	COG0157	Belongs to the NadC ModD family
LCQ53_RS04320	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LCQ53_RS04325	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LCQ53_RS04340	COG1070	Carbohydrate kinase
LCQ53_RS04345	COG1063	alcohol dehydrogenase
LCQ53_RS04350	COG3716	PTS system mannose fructose sorbose family IID component
LCQ53_RS04360	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCQ53_RS04360	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCQ53_RS04365	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCQ53_RS04395	COG0191	fructose-bisphosphate aldolase activity
LCQ53_RS04405	COG3775	system Galactitol-specific IIC component
LCQ53_RS04410	COG3414	Phosphotransferase system galactitol-specific IIB component
LCQ53_RS04420	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCQ53_RS04425	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCQ53_RS04425	COG3711	transcriptional antiterminator
LCQ53_RS04565	COG2868	ribosomal protein
LCQ53_RS04590	COG5484	DNA packaging
LCQ53_RS04590	COG3728	DNA packaging
LCQ53_RS04665	COG1484	DNA-dependent DNA replication
LCQ53_RS04725	COG3617	BRO family, N-terminal domain
LCQ53_RS04735	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LCQ53_RS04765	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LCQ53_RS04770	COG1283	sodium-dependent phosphate transmembrane transporter activity
LCQ53_RS04780	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LCQ53_RS04790	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LCQ53_RS04795	COG0561	phosphatase activity
LCQ53_RS04805	COG1309	transcriptional regulator
LCQ53_RS04810	COG2814	Major facilitator Superfamily
LCQ53_RS04815	COG1489	DNA binding
LCQ53_RS04825	COG1116	anion transmembrane transporter activity
LCQ53_RS04830	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LCQ53_RS04845	COG0613	PHP domain protein
LCQ53_RS04850	COG0534	Mate efflux family protein
LCQ53_RS04880	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LCQ53_RS04885	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
LCQ53_RS04895	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCQ53_RS04900	COG3711	transcriptional antiterminator
LCQ53_RS04910	COG1349	DNA-binding transcription factor activity
LCQ53_RS04915	COG1063	alcohol dehydrogenase
LCQ53_RS04930	COG2211	Major facilitator Superfamily
LCQ53_RS04935	COG3622	Belongs to the hyi family
LCQ53_RS04940	COG0673	inositol 2-dehydrogenase activity
LCQ53_RS04945	COG1609	Transcriptional regulator
LCQ53_RS04950	COG2213	PTS system mannitol-specific
LCQ53_RS04950	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCQ53_RS04960	COG1063	alcohol dehydrogenase
LCQ53_RS04970	COG0504	CTP synthase activity
LCQ53_RS04985	COG2376	Dihydroxyacetone kinase
LCQ53_RS04995	COG0698	ribose 5-phosphate isomerase
LCQ53_RS05000	COG0546	phosphoglycolate phosphatase activity
LCQ53_RS05010	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LCQ53_RS05015	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LCQ53_RS05020	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LCQ53_RS05020	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LCQ53_RS05020	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCQ53_RS05035	COG0791	NLP P60 protein
LCQ53_RS05035	COG0741	lytic transglycosylase activity
LCQ53_RS05045	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LCQ53_RS05055	COG2199	diguanylate cyclase activity
LCQ53_RS05060	COG1028	Short-chain dehydrogenase reductase Sdr
LCQ53_RS05080	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LCQ53_RS05085	COG0741	lytic transglycosylase activity
LCQ53_RS05085	COG0791	NLP P60 protein
LCQ53_RS05165	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
LCQ53_RS05175	COG1234	tRNA 3'-trailer cleavage
LCQ53_RS05180	COG0456	acetyltransferase
LCQ53_RS05185	COG1214	PFAM Peptidase M22, glycoprotease
LCQ53_RS05190	COG0802	atpase or kinase
LCQ53_RS05200	COG2002	toxin-antitoxin pair type II binding
LCQ53_RS05215	COG3850	Histidine kinase
LCQ53_RS05215	COG4999	Histidine kinase
LCQ53_RS05215	COG2205	protein histidine kinase activity
LCQ53_RS05215	COG3437	response regulator, receiver
LCQ53_RS05245	COG0793	Belongs to the peptidase S41A family
LCQ53_RS05245	COG3409	Peptidoglycan-binding domain 1 protein
LCQ53_RS05255	COG2610	gluconate transmembrane transporter activity
LCQ53_RS05265	COG2030	dehydratase
LCQ53_RS05270	COG0583	DNA-binding transcription factor activity
LCQ53_RS05275	COG0739	heme binding
LCQ53_RS05280	COG2177	Part of the ABC transporter FtsEX involved in
LCQ53_RS05285	COG2884	Cell division ATP-binding protein ftsE
LCQ53_RS05290	COG3835	regulator
LCQ53_RS05295	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LCQ53_RS05305	COG0300	oxidoreductase activity
LCQ53_RS05310	COG2183	response to ionizing radiation
LCQ53_RS05325	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
LCQ53_RS05330	COG0460	homoserine dehydrogenase
LCQ53_RS05335	COG4492	Belongs to the UPF0735 family
LCQ53_RS05345	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LCQ53_RS05350	COG0653	protein targeting
LCQ53_RS05355	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LCQ53_RS05360	COG0492	ferredoxin-NADP+ reductase activity
LCQ53_RS05370	COG0697	spore germination
LCQ53_RS05375	COG2207	Transcriptional regulator
LCQ53_RS05375	COG1917	Cupin 2, conserved barrel domain protein
LCQ53_RS05380	COG0640	Transcriptional regulator
LCQ53_RS05390	COG2252	PERMEase
LCQ53_RS05395	COG4447	cellulose binding
LCQ53_RS05415	COG0488	(ABC) transporter
LCQ53_RS05425	COG1285	pathogenesis
LCQ53_RS05430	COG0110	maltose O-acetyltransferase activity
LCQ53_RS05435	COG1193	negative regulation of DNA recombination
LCQ53_RS05445	COG2190	(PTS) system
LCQ53_RS05445	COG1263	PTS System
LCQ53_RS05445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCQ53_RS05450	COG3711	transcriptional antiterminator
LCQ53_RS05455	COG1263	PTS System
LCQ53_RS05455	COG2190	(PTS) system
LCQ53_RS05455	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCQ53_RS05460	COG2378	regulation of single-species biofilm formation
LCQ53_RS05475	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LCQ53_RS05480	COG1328	CTP reductase activity
LCQ53_RS05480	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LCQ53_RS05490	COG0101	tRNA pseudouridine synthase activity
LCQ53_RS05495	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LCQ53_RS05500	COG1122	ATPase activity
LCQ53_RS05505	COG1122	ATPase activity
LCQ53_RS05515	COG0203	ribosomal protein L17
LCQ53_RS05520	COG0202	RNA polymerase activity
LCQ53_RS05525	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LCQ53_RS05530	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LCQ53_RS05540	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LCQ53_RS05545	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LCQ53_RS05570	COG1841	ribosomal large subunit assembly
LCQ53_RS05585	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LCQ53_RS05590	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LCQ53_RS05595	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LCQ53_RS05600	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LCQ53_RS05605	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LCQ53_RS05610	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LCQ53_RS05615	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LCQ53_RS05620	COG0255	Belongs to the universal ribosomal protein uL29 family
LCQ53_RS05625	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LCQ53_RS05635	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LCQ53_RS05645	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LCQ53_RS05660	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LCQ53_RS05665	COG0051	transcription antitermination factor activity, RNA binding
LCQ53_RS05680	COG0656	L-ascorbic acid biosynthetic process
LCQ53_RS05690	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
LCQ53_RS05695	COG2376	Dihydroxyacetone kinase
LCQ53_RS05700	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LCQ53_RS05705	COG1349	DNA-binding transcription factor activity
LCQ53_RS05720	COG0439	Biotin carboxylase
LCQ53_RS05730	COG0511	ligase activity, forming carbon-carbon bonds
LCQ53_RS05735	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LCQ53_RS05740	COG1028	Short-chain dehydrogenase reductase Sdr
LCQ53_RS05745	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LCQ53_RS05750	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LCQ53_RS05755	COG1063	alcohol dehydrogenase
LCQ53_RS05780	COG1592	Rubrerythrin
LCQ53_RS05780	COG1773	rubredoxin
LCQ53_RS05800	COG0513	Belongs to the DEAD box helicase family
LCQ53_RS05810	COG1342	Belongs to the UPF0251 family
LCQ53_RS05830	COG2827	Endonuclease containing a URI domain
LCQ53_RS05840	COG2385	sporulation resulting in formation of a cellular spore
LCQ53_RS05860	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LCQ53_RS05870	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
LCQ53_RS05875	COG3716	PTS system mannose fructose sorbose family IID component
LCQ53_RS05880	COG3715	PTS system
LCQ53_RS05900	COG3933	PFAM sigma-54 factor interaction domain-containing protein
LCQ53_RS05900	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
LCQ53_RS05910	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LCQ53_RS05925	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LCQ53_RS05940	COG0564	pseudouridine synthase activity
LCQ53_RS05945	COG0745	RESPONSE REGULATOR receiver
LCQ53_RS05950	COG5002	protein histidine kinase activity
LCQ53_RS05955	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LCQ53_RS05960	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LCQ53_RS05965	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LCQ53_RS05970	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LCQ53_RS06005	COG0488	(ABC) transporter
LCQ53_RS06010	COG1349	DNA-binding transcription factor activity
LCQ53_RS06020	COG1737	Transcriptional regulator
LCQ53_RS06025	COG1263	PTS System
LCQ53_RS06025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCQ53_RS06025	COG2190	(PTS) system
LCQ53_RS06030	COG1486	melibiose metabolic process
LCQ53_RS06050	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCQ53_RS06050	COG1263	PTS System
LCQ53_RS06055	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LCQ53_RS06060	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LCQ53_RS06065	COG2207	Transcriptional regulator
LCQ53_RS06065	COG3708	Transcriptional regulator
LCQ53_RS06075	COG0726	polysaccharide deacetylase
LCQ53_RS06080	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LCQ53_RS06085	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LCQ53_RS06095	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LCQ53_RS06100	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LCQ53_RS06110	COG0537	adenosine 5'-monophosphoramidase activity
LCQ53_RS06115	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LCQ53_RS06120	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LCQ53_RS06125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LCQ53_RS06130	COG3290	protein histidine kinase activity
LCQ53_RS06135	COG0705	Rhomboid family
LCQ53_RS06135	COG0457	Tetratricopeptide repeat
LCQ53_RS06190	COG0159	tryptophan synthase activity
LCQ53_RS06205	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCQ53_RS06215	COG4086	secreted protein
LCQ53_RS06230	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LCQ53_RS06245	COG0765	amino acid transport
LCQ53_RS06250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LCQ53_RS06255	COG1464	Belongs to the NlpA lipoprotein family
LCQ53_RS06260	COG1194	a g-specific adenine glycosylase
LCQ53_RS06265	COG1040	competence protein
LCQ53_RS06295	COG3732	PTS system glucitol sorbitol-specific
LCQ53_RS06300	COG3730	PTS system glucitol sorbitol-specific
LCQ53_RS06325	COG3732	PTS system glucitol sorbitol-specific
LCQ53_RS06330	COG3730	PTS system glucitol sorbitol-specific
LCQ53_RS06350	COG2378	regulation of single-species biofilm formation
LCQ53_RS06355	COG0693	protein deglycase activity
LCQ53_RS06360	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LCQ53_RS06370	COG0116	Belongs to the methyltransferase superfamily
LCQ53_RS06370	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LCQ53_RS06380	COG0726	polysaccharide deacetylase
LCQ53_RS06405	COG0784	Response regulator, receiver
LCQ53_RS06405	COG2205	protein histidine kinase activity
LCQ53_RS06405	COG5002	protein histidine kinase activity
LCQ53_RS06410	COG4999	Histidine kinase
LCQ53_RS06410	COG3850	Histidine kinase
LCQ53_RS06410	COG3437	response regulator, receiver
LCQ53_RS06410	COG2205	protein histidine kinase activity
LCQ53_RS06420	COG2199	diguanylate cyclase activity
LCQ53_RS06420	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
LCQ53_RS06450	COG1704	LemA family
LCQ53_RS06460	COG1773	rubredoxin
LCQ53_RS06460	COG1592	Rubrerythrin
LCQ53_RS06475	COG1253	flavin adenine dinucleotide binding
LCQ53_RS06490	COG1607	acyl-coa hydrolase
LCQ53_RS06500	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LCQ53_RS06510	COG2086	electron transfer activity
LCQ53_RS06515	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LCQ53_RS06520	COG1960	acyl-CoA dehydrogenase activity
LCQ53_RS06530	COG0789	Transcriptional regulator
LCQ53_RS06530	COG4978	Transcriptional regulator
LCQ53_RS06560	COG0167	dihydroorotate dehydrogenase activity
LCQ53_RS06560	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LCQ53_RS06565	COG0493	'glutamate synthase
LCQ53_RS06585	COG3842	ATPase activity
LCQ53_RS06610	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LCQ53_RS06615	COG0800	Aldolase
LCQ53_RS06620	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LCQ53_RS06625	COG1028	Short-chain dehydrogenase reductase Sdr
LCQ53_RS06645	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LCQ53_RS06650	COG2186	Transcriptional regulator
LCQ53_RS06660	COG0534	Mate efflux family protein
LCQ53_RS06665	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LCQ53_RS06670	COG3716	PTS system mannose fructose sorbose family IID component
LCQ53_RS06675	COG3715	PTS system
LCQ53_RS06695	COG2222	sugar isomerase
LCQ53_RS06700	COG2188	Transcriptional regulator
LCQ53_RS06720	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LCQ53_RS06725	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LCQ53_RS06730	COG0049	tRNA binding
LCQ53_RS06735	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LCQ53_RS06740	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LCQ53_RS06745	COG0085	RNA polymerase activity
LCQ53_RS06750	COG0222	ribosome binding
LCQ53_RS06765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LCQ53_RS06770	COG1126	abc transporter atp-binding protein
LCQ53_RS06775	COG0765	amino acid transport
LCQ53_RS06780	COG0765	amino acid transport
LCQ53_RS06820	COG2226	methyltransferase
LCQ53_RS06830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LCQ53_RS06910	COG0081	regulation of translation
LCQ53_RS06920	COG0250	Participates in transcription elongation, termination and antitermination
LCQ53_RS06930	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LCQ53_RS06935	COG0602	queuosine metabolic process
LCQ53_RS06945	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LCQ53_RS06960	COG0697	spore germination
LCQ53_RS06965	COG1802	Transcriptional regulator
LCQ53_RS06970	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LCQ53_RS06980	COG4466	Protein conserved in bacteria
LCQ53_RS06985	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LCQ53_RS07000	COG1592	Rubrerythrin
LCQ53_RS07020	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LCQ53_RS07030	COG0756	dUTP diphosphatase activity
LCQ53_RS07035	COG0166	Belongs to the GPI family
LCQ53_RS07040	COG0726	polysaccharide deacetylase
LCQ53_RS07050	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LCQ53_RS07060	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LCQ53_RS07080	COG1082	Xylose isomerase domain protein TIM barrel
LCQ53_RS07085	COG0673	inositol 2-dehydrogenase activity
LCQ53_RS07090	COG1082	Xylose isomerase domain protein TIM barrel
LCQ53_RS07095	COG0789	Transcriptional regulator
LCQ53_RS07100	COG2207	Transcriptional regulator
LCQ53_RS07100	COG1917	Cupin 2, conserved barrel domain protein
LCQ53_RS07115	COG0647	UMP catabolic process
LCQ53_RS07125	COG0371	Dehydrogenase
LCQ53_RS07130	COG3775	system Galactitol-specific IIC component
LCQ53_RS07140	COG2213	PTS system mannitol-specific
LCQ53_RS07140	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCQ53_RS07145	COG3711	transcriptional antiterminator
LCQ53_RS07145	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCQ53_RS07150	COG1105	Belongs to the carbohydrate kinase PfkB family
LCQ53_RS07155	COG1349	DNA-binding transcription factor activity
LCQ53_RS07165	COG1136	(ABC) transporter
LCQ53_RS07180	COG2205	protein histidine kinase activity
LCQ53_RS07185	COG0745	RESPONSE REGULATOR receiver
LCQ53_RS07190	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LCQ53_RS07200	COG1475	DNA binding
LCQ53_RS07205	COG1192	Involved in chromosome partitioning
LCQ53_RS07210	COG0018	arginyl-trna synthetase
LCQ53_RS07225	COG0357	Ribosomal RNA small subunit methyltransferase G
LCQ53_RS07230	COG0445	tRNA wobble uridine modification
LCQ53_RS07235	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LCQ53_RS07240	COG1847	R3H domain protein
LCQ53_RS07245	COG0706	membrane insertase activity
LCQ53_RS07250	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
LCQ53_RS07255	COG0594	ribonuclease P activity
LCQ53_RS07260	COG0230	Belongs to the bacterial ribosomal protein bL34 family
LCQ53_RS07265	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LCQ53_RS07270	COG0592	DNA-directed DNA polymerase activity
LCQ53_RS07285	COG0187	DNA topoisomerase II activity
LCQ53_RS07290	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LCQ53_RS07325	COG1070	Carbohydrate kinase
LCQ53_RS07380	COG0534	Mate efflux family protein
LCQ53_RS07385	COG1748	Saccharopine dehydrogenase
LCQ53_RS07400	COG3711	transcriptional antiterminator
LCQ53_RS07415	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCQ53_RS07425	COG1609	Transcriptional regulator
LCQ53_RS07455	COG2390	Transcriptional regulator
LCQ53_RS07465	COG0017	Asparaginyl-tRNA synthetase
LCQ53_RS07475	COG1610	YqeY-like protein
LCQ53_RS07485	COG0069	glutamate synthase activity
LCQ53_RS07490	COG0084	hydrolase, TatD family'
LCQ53_RS07495	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LCQ53_RS07505	COG0590	tRNA wobble adenosine to inosine editing
LCQ53_RS07510	COG0598	Magnesium transport protein CorA
LCQ53_RS07535	COG3775	system Galactitol-specific IIC component
LCQ53_RS07545	COG1063	alcohol dehydrogenase
LCQ53_RS07555	COG1028	Short-chain dehydrogenase reductase Sdr
LCQ53_RS07560	COG2357	RelA SpoT domain protein
LCQ53_RS07580	COG5566	PFAM Mor transcription activator
LCQ53_RS07590	COG4717	serine-type aminopeptidase activity
LCQ53_RS07595	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LCQ53_RS07600	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LCQ53_RS07615	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LCQ53_RS07620	COG2088	sporulation resulting in formation of a cellular spore
LCQ53_RS07730	COG1982	Orn Lys Arg decarboxylase major
LCQ53_RS07735	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LCQ53_RS07740	COG0470	DNA polymerase III
LCQ53_RS07745	COG1774	PSP1 C-terminal conserved region
LCQ53_RS07750	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
LCQ53_RS07755	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LCQ53_RS07760	COG2002	toxin-antitoxin pair type II binding
LCQ53_RS07780	COG1846	Transcriptional regulator
LCQ53_RS07785	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
LCQ53_RS07810	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCQ53_RS07820	COG3716	PTS system mannose fructose sorbose family IID component
LCQ53_RS07825	COG1063	alcohol dehydrogenase
LCQ53_RS07840	COG4607	ABC-type enterochelin transport system periplasmic component
LCQ53_RS07845	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LCQ53_RS07850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LCQ53_RS07855	COG1120	ATPase activity
LCQ53_RS07885	COG3732	PTS system glucitol sorbitol-specific
LCQ53_RS07890	COG3730	PTS system glucitol sorbitol-specific
LCQ53_RS07900	COG1063	alcohol dehydrogenase
LCQ53_RS07905	COG2390	Transcriptional regulator
LCQ53_RS07920	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
LCQ53_RS07935	COG1193	negative regulation of DNA recombination
LCQ53_RS07940	COG3481	metal-dependent phosphohydrolase, HD sub domain
LCQ53_RS07990	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LCQ53_RS07995	COG2226	methyltransferase
LCQ53_RS08010	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LCQ53_RS08015	COG3706	GGDEF domain
LCQ53_RS08055	COG2315	Protein conserved in bacteria
LCQ53_RS08065	COG1051	belongs to the nudix hydrolase family
LCQ53_RS08070	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LCQ53_RS08075	COG0785	Cytochrome C biogenesis protein
LCQ53_RS08080	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LCQ53_RS08100	COG1454	alcohol dehydrogenase
LCQ53_RS08120	COG3022	response to hydroperoxide
LCQ53_RS08145	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LCQ53_RS08165	COG4974	Belongs to the 'phage' integrase family
LCQ53_RS08210	COG0270	DNA (cytosine-5-)-methyltransferase activity
LCQ53_RS08220	COG1196	nuclear chromosome segregation
LCQ53_RS08245	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LCQ53_RS08255	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LCQ53_RS08260	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LCQ53_RS08265	COG1116	anion transmembrane transporter activity
LCQ53_RS08270	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCQ53_RS08280	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LCQ53_RS08300	COG3775	system Galactitol-specific IIC component
LCQ53_RS08305	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LCQ53_RS08315	COG1063	alcohol dehydrogenase
LCQ53_RS08345	COG1063	alcohol dehydrogenase
LCQ53_RS08350	COG3716	PTS system mannose fructose sorbose family IID component
LCQ53_RS08360	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCQ53_RS08365	COG1028	Short-chain dehydrogenase reductase Sdr
LCQ53_RS08370	COG2188	Transcriptional regulator
LCQ53_RS08385	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
LCQ53_RS08390	COG2084	Dehydrogenase
LCQ53_RS08400	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LCQ53_RS08440	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LCQ53_RS08470	COG0514	ATP-dependent DNA helicase (RecQ)
LCQ53_RS08475	COG0242	peptide deformylase activity
LCQ53_RS08490	COG0129	dihydroxy-acid dehydratase activity
LCQ53_RS08495	COG1063	alcohol dehydrogenase
LCQ53_RS08500	COG1063	alcohol dehydrogenase
LCQ53_RS08505	COG0436	Aminotransferase
LCQ53_RS08510	COG0531	amino acid
LCQ53_RS08525	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LCQ53_RS08530	COG0800	Aldolase
LCQ53_RS08535	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LCQ53_RS08540	COG1132	(ABC) transporter
LCQ53_RS08555	COG0534	Mate efflux family protein
LCQ53_RS08575	COG3300	MHYT domain
LCQ53_RS08575	COG5001	Diguanylate cyclase
LCQ53_RS08590	COG0534	Mate efflux family protein
LCQ53_RS08595	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
LCQ53_RS08600	COG0193	aminoacyl-tRNA hydrolase activity
LCQ53_RS08605	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LCQ53_RS08625	COG0629	single-stranded DNA binding
LCQ53_RS08630	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LCQ53_RS08635	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
LCQ53_RS08640	COG0359	binds to the 23S rRNA
LCQ53_RS08645	COG0305	Participates in initiation and elongation during chromosome replication
LCQ53_RS08655	COG2768	binding domain, Protein
LCQ53_RS08670	COG3414	Phosphotransferase system galactitol-specific IIB component
LCQ53_RS08675	COG3775	system Galactitol-specific IIC component
LCQ53_RS08680	COG2376	Dihydroxyacetone kinase
LCQ53_RS08695	COG2376	Dihydroxyacetone kinase
LCQ53_RS08715	COG0673	inositol 2-dehydrogenase activity
LCQ53_RS08730	COG0860	N-Acetylmuramoyl-L-alanine amidase
LCQ53_RS08735	COG1115	amino acid carrier protein
LCQ53_RS08740	COG0009	L-threonylcarbamoyladenylate synthase
LCQ53_RS08765	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LCQ53_RS08770	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LCQ53_RS08775	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LCQ53_RS08780	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LCQ53_RS08785	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LCQ53_RS08790	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LCQ53_RS08795	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LCQ53_RS08805	COG5001	Diguanylate cyclase
LCQ53_RS08810	COG2954	triphosphatase activity
LCQ53_RS08815	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LCQ53_RS08825	COG0488	(ABC) transporter
LCQ53_RS08835	COG0673	inositol 2-dehydrogenase activity
LCQ53_RS08840	COG2972	Histidine kinase
LCQ53_RS08845	COG4753	response regulator
LCQ53_RS08845	COG2207	Transcriptional regulator
LCQ53_RS08850	COG1082	Xylose isomerase domain protein TIM barrel
LCQ53_RS08875	COG0628	permease
LCQ53_RS08885	COG3279	Response regulator of the LytR AlgR family
LCQ53_RS08900	COG0432	Pfam Uncharacterised protein family UPF0047
LCQ53_RS08910	COG4509	Sortase family
LCQ53_RS08930	COG2996	Protein conserved in bacteria
LCQ53_RS08935	COG3956	TIGRFAM MazG family protein
LCQ53_RS08945	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LCQ53_RS08965	COG3711	transcriptional antiterminator
LCQ53_RS08965	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCQ53_RS09000	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LCQ53_RS09030	COG0446	pyridine nucleotide-disulphide oxidoreductase
LCQ53_RS09055	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LCQ53_RS09060	COG1301	dicarboxylic acid transport
LCQ53_RS09075	COG0534	Mate efflux family protein
LCQ53_RS09095	COG1278	Cold shock
LCQ53_RS09190	COG0281	malic enzyme
LCQ53_RS09200	COG0534	Mate efflux family protein
LCQ53_RS09220	COG1640	4-alpha-glucanotransferase
LCQ53_RS09225	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LCQ53_RS09230	COG2176	DNA-directed DNA polymerase activity
LCQ53_RS09235	COG2720	vancomycin resistance protein
LCQ53_RS09240	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LCQ53_RS09245	COG1522	sequence-specific DNA binding
LCQ53_RS09250	COG0436	Aminotransferase
LCQ53_RS09275	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LCQ53_RS09280	COG0617	tRNA 3'-terminal CCA addition
LCQ53_RS09290	COG1181	Belongs to the D-alanine--D-alanine ligase family
LCQ53_RS09295	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LCQ53_RS09305	COG0671	phosphoesterase, PA-phosphatase related
LCQ53_RS09335	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LCQ53_RS09345	COG1410	methionine synthase
LCQ53_RS09345	COG0646	methionine synthase
LCQ53_RS09350	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
LCQ53_RS09355	COG1687	branched-chain amino acid
LCQ53_RS09405	COG3706	GGDEF domain
LCQ53_RS09480	COG1063	alcohol dehydrogenase
LCQ53_RS09485	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LCQ53_RS09490	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LCQ53_RS09495	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCQ53_RS09500	COG1063	alcohol dehydrogenase
LCQ53_RS09505	COG1434	Gram-negative-bacterium-type cell wall biogenesis
LCQ53_RS09510	COG1760	l-serine dehydratase
LCQ53_RS09515	COG1760	l-serine dehydratase
LCQ53_RS09525	COG1737	Transcriptional regulator
LCQ53_RS09530	COG1105	Belongs to the carbohydrate kinase PfkB family
LCQ53_RS09535	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LCQ53_RS09535	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LCQ53_RS09535	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCQ53_RS09540	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LCQ53_RS09540	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCQ53_RS09540	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LCQ53_RS09545	COG1349	DNA-binding transcription factor activity
LCQ53_RS09550	COG1072	(Pantothenic acid kinase))
LCQ53_RS09555	COG1063	alcohol dehydrogenase
LCQ53_RS09565	COG1408	metallophosphoesterase
LCQ53_RS09570	COG1733	regulation of RNA biosynthetic process
LCQ53_RS09605	COG0697	spore germination
LCQ53_RS09615	COG1691	(AIR) carboxylase
LCQ53_RS09620	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
LCQ53_RS09625	COG1606	tRNA processing
LCQ53_RS09630	COG0310	cobalt ion transport
LCQ53_RS09640	COG1122	ATPase activity
LCQ53_RS09645	COG0789	Transcriptional regulator
LCQ53_RS09655	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LCQ53_RS09675	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LCQ53_RS09685	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
LCQ53_RS09685	COG3933	PFAM sigma-54 factor interaction domain-containing protein
LCQ53_RS09700	COG2207	Transcriptional regulator
LCQ53_RS09720	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LCQ53_RS09725	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LCQ53_RS09730	COG1024	Enoyl-CoA hydratase
LCQ53_RS09755	COG1979	alcohol dehydrogenase
LCQ53_RS09760	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCQ53_RS09765	COG3715	PTS system
LCQ53_RS09770	COG3716	PTS system mannose fructose sorbose family IID component
LCQ53_RS09780	COG1063	alcohol dehydrogenase
LCQ53_RS09790	COG0561	phosphatase activity
LCQ53_RS09820	COG1598	PFAM Uncharacterised protein family UPF0150
LCQ53_RS09825	COG0038	chloride channel
LCQ53_RS09835	COG0561	phosphatase activity
LCQ53_RS09845	COG1686	Belongs to the peptidase S11 family
LCQ53_RS09860	COG1597	lipid kinase activity
LCQ53_RS09870	COG4251	negative regulation of phosphorylation
LCQ53_RS09870	COG2203	Gaf domain
LCQ53_RS09870	COG5001	Diguanylate cyclase
LCQ53_RS09870	COG3706	GGDEF domain
LCQ53_RS09880	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LCQ53_RS09885	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCQ53_RS09890	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
LCQ53_RS09890	COG3933	PFAM sigma-54 factor interaction domain-containing protein
LCQ53_RS09905	COG1063	alcohol dehydrogenase
LCQ53_RS09915	COG3715	PTS system
LCQ53_RS09930	COG0667	Aldo Keto reductase
LCQ53_RS09950	COG1882	Formate acetyltransferase
LCQ53_RS09955	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LCQ53_RS09960	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LCQ53_RS09965	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCQ53_RS09965	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCQ53_RS09970	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCQ53_RS09975	COG3716	PTS system mannose fructose sorbose family IID component
LCQ53_RS09980	COG2390	Transcriptional regulator
LCQ53_RS09985	COG0657	acetylesterase activity
LCQ53_RS09990	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LCQ53_RS09990	COG0512	Glutamine amidotransferase of anthranilate synthase
LCQ53_RS09995	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LCQ53_RS10000	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LCQ53_RS10005	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LCQ53_RS10010	COG3973	AAA domain
LCQ53_RS10015	COG2207	Transcriptional regulator
LCQ53_RS10030	COG1115	amino acid carrier protein
LCQ53_RS10055	COG0004	ammonium transporteR
LCQ53_RS10065	COG0697	spore germination
LCQ53_RS10075	COG5492	domain, Protein
LCQ53_RS10080	COG1959	2 iron, 2 sulfur cluster binding
LCQ53_RS10085	COG1511	domain protein
LCQ53_RS10105	COG0116	Belongs to the methyltransferase superfamily
LCQ53_RS10110	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LCQ53_RS10150	COG0596	Alpha beta hydrolase
LCQ53_RS10150	COG2945	thiolester hydrolase activity
LCQ53_RS10180	COG2252	PERMEase
LCQ53_RS10185	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LCQ53_RS10190	COG1929	Belongs to the glycerate kinase type-1 family
LCQ53_RS10195	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LCQ53_RS10205	COG0784	Response regulator, receiver
LCQ53_RS10205	COG2205	protein histidine kinase activity
LCQ53_RS10205	COG2198	Histidine kinase
LCQ53_RS10225	COG1174	glycine betaine transport
LCQ53_RS10230	COG0517	IMP dehydrogenase activity
LCQ53_RS10230	COG1125	glycine betaine transport
LCQ53_RS10260	COG1979	alcohol dehydrogenase
LCQ53_RS10290	COG3732	PTS system glucitol sorbitol-specific
LCQ53_RS10295	COG3732	PTS system glucitol sorbitol-specific
LCQ53_RS10305	COG2188	Transcriptional regulator
LCQ53_RS10325	COG1968	undecaprenyl-diphosphatase activity
LCQ53_RS10355	COG1063	alcohol dehydrogenase
LCQ53_RS10370	COG1234	tRNA 3'-trailer cleavage
LCQ53_RS10380	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LCQ53_RS10395	COG0561	phosphatase activity
LCQ53_RS10410	COG3437	response regulator, receiver
LCQ53_RS10415	COG2078	PFAM AMMECR1 domain protein
LCQ53_RS10415	COG3885	ferrous iron binding
LCQ53_RS10420	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LCQ53_RS10435	COG2202	Pas domain
LCQ53_RS10435	COG2200	EAL domain
LCQ53_RS10435	COG2199	diguanylate cyclase activity
LCQ53_RS10440	COG0768	penicillin binding
LCQ53_RS10460	COG0372	Belongs to the citrate synthase family
LCQ53_RS10485	COG0460	homoserine dehydrogenase
LCQ53_RS10490	COG0697	spore germination
LCQ53_RS10510	COG2205	protein histidine kinase activity
LCQ53_RS10515	COG0745	RESPONSE REGULATOR receiver
LCQ53_RS10520	COG2205	protein histidine kinase activity
LCQ53_RS10535	COG0640	Transcriptional regulator
LCQ53_RS10550	COG0656	L-ascorbic acid biosynthetic process
LCQ53_RS10570	COG1136	(ABC) transporter
LCQ53_RS10580	COG0745	RESPONSE REGULATOR receiver
LCQ53_RS10585	COG0642	Histidine kinase
LCQ53_RS10595	COG0723	plastoquinol--plastocyanin reductase activity
LCQ53_RS10595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LCQ53_RS10610	COG1331	Highly conserved protein containing a thioredoxin domain
LCQ53_RS10625	COG2205	protein histidine kinase activity
LCQ53_RS10630	COG1472	Belongs to the glycosyl hydrolase 3 family
LCQ53_RS10635	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LCQ53_RS10640	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LCQ53_RS10645	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LCQ53_RS10650	COG1597	lipid kinase activity
LCQ53_RS10660	COG1609	Transcriptional regulator
LCQ53_RS10670	COG3959	Transketolase, thiamine diphosphate binding domain
LCQ53_RS10675	COG3958	Transketolase
LCQ53_RS10680	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LCQ53_RS10695	COG1368	sulfuric ester hydrolase activity
LCQ53_RS10700	COG0544	peptidyl-prolyl cis-trans isomerase activity
LCQ53_RS10710	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LCQ53_RS10715	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LCQ53_RS10720	COG0285	dihydrofolate synthase activity
LCQ53_RS10730	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LCQ53_RS10735	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LCQ53_RS10735	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LCQ53_RS10740	COG0077	Prephenate dehydratase
LCQ53_RS10740	COG1605	Chorismate mutase
LCQ53_RS10745	COG1368	sulfuric ester hydrolase activity
LCQ53_RS10750	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LCQ53_RS10755	COG0681	Belongs to the peptidase S26 family
LCQ53_RS10765	COG0251	oxidation-reduction process
LCQ53_RS10770	COG3706	GGDEF domain
LCQ53_RS10775	COG0534	Mate efflux family protein
LCQ53_RS10780	COG0366	Alpha amylase catalytic
LCQ53_RS10785	COG3711	transcriptional antiterminator
LCQ53_RS10785	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCQ53_RS10790	COG3775	system Galactitol-specific IIC component
LCQ53_RS10800	COG3414	Phosphotransferase system galactitol-specific IIB component
LCQ53_RS10805	COG1063	alcohol dehydrogenase
LCQ53_RS10810	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LCQ53_RS10815	COG1063	alcohol dehydrogenase
LCQ53_RS10820	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LCQ53_RS10825	COG1082	Xylose isomerase domain protein TIM barrel
LCQ53_RS10830	COG1105	Belongs to the carbohydrate kinase PfkB family
LCQ53_RS10860	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LCQ53_RS10860	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LCQ53_RS10870	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LCQ53_RS10890	COG1609	Transcriptional regulator
LCQ53_RS10895	COG2211	Major facilitator Superfamily
LCQ53_RS10900	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LCQ53_RS10910	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
LCQ53_RS10915	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LCQ53_RS10930	COG2033	superoxide reductase activity
LCQ53_RS10940	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LCQ53_RS10945	COG0367	asparagine synthase
LCQ53_RS10990	COG2378	regulation of single-species biofilm formation
LCQ53_RS11000	COG1464	Belongs to the NlpA lipoprotein family
LCQ53_RS11005	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LCQ53_RS11010	COG2011	ABC-type metal ion transport system permease component
LCQ53_RS11015	COG0277	FAD linked oxidase domain protein
LCQ53_RS11025	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LCQ53_RS11060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LCQ53_RS11070	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
LCQ53_RS11080	COG1773	rubredoxin
LCQ53_RS11085	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LCQ53_RS11090	COG0288	reversible hydration of carbon dioxide
LCQ53_RS11095	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LCQ53_RS11130	COG1395	domain, Protein
LCQ53_RS11350	COG3628	GPW Gp25 family protein
LCQ53_RS11355	COG3299	homolog of phage Mu protein gp47
LCQ53_RS11440	COG1418	mRNA catabolic process
LCQ53_RS11450	COG2213	PTS system mannitol-specific
LCQ53_RS11450	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCQ53_RS11455	COG1349	DNA-binding transcription factor activity
LCQ53_RS11475	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LCQ53_RS11490	COG0588	phosphoglycerate mutase activity
LCQ53_RS11500	COG1473	amidohydrolase
LCQ53_RS11530	COG1131	(ABC) transporter
LCQ53_RS11535	COG1725	Transcriptional regulator
LCQ53_RS11555	COG0539	negative regulation of cytoplasmic translation
LCQ53_RS11560	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LCQ53_RS11565	COG0343	queuine tRNA-ribosyltransferase activity
LCQ53_RS11570	COG1862	Preprotein translocase
LCQ53_RS11575	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LCQ53_RS11585	COG0613	PHP domain protein
LCQ53_RS11595	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LCQ53_RS11600	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LCQ53_RS11600	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LCQ53_RS11605	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
LCQ53_RS11605	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LCQ53_RS11610	COG0561	phosphatase activity
LCQ53_RS11615	COG0420	3'-5' exonuclease activity
LCQ53_RS11620	COG0419	ATPase involved in DNA repair
LCQ53_RS11640	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
LCQ53_RS11660	COG1187	pseudouridine synthase activity
LCQ53_RS11665	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LCQ53_RS11675	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
LCQ53_RS11680	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LCQ53_RS11685	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCQ53_RS11685	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LCQ53_RS11685	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LCQ53_RS11700	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LCQ53_RS11725	COG1063	alcohol dehydrogenase
LCQ53_RS11735	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCQ53_RS11735	COG3711	transcriptional antiterminator
LCQ53_RS11740	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCQ53_RS11745	COG0561	phosphatase activity
LCQ53_RS11750	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LCQ53_RS11755	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LCQ53_RS11760	COG0658	competence protein
LCQ53_RS11760	COG2333	competence protein COMEC
LCQ53_RS11770	COG0347	Belongs to the P(II) protein family
LCQ53_RS11775	COG3842	ATPase activity
LCQ53_RS11785	COG1177	transmembrane transport
LCQ53_RS11800	COG2267	carboxylic ester hydrolase activity
LCQ53_RS11810	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LCQ53_RS11830	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LCQ53_RS11830	COG0574	Belongs to the PEP-utilizing enzyme family
LCQ53_RS11845	COG0148	phosphopyruvate hydratase activity
LCQ53_RS11860	COG2199	diguanylate cyclase activity
LCQ53_RS11865	COG1321	iron dependent repressor
LCQ53_RS11880	COG1918	ferrous iron import across plasma membrane
LCQ53_RS11880	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
LCQ53_RS11920	COG0426	domain, Protein
LCQ53_RS11925	COG1960	acyl-CoA dehydrogenase activity
LCQ53_RS11940	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LCQ53_RS11940	COG2080	2 iron, 2 sulfur cluster binding
LCQ53_RS11945	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LCQ53_RS11950	COG0673	inositol 2-dehydrogenase activity
LCQ53_RS11955	COG1349	DNA-binding transcription factor activity
LCQ53_RS11965	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LCQ53_RS11985	COG0385	Bile acid
LCQ53_RS11990	COG1595	DNA-templated transcription, initiation
LCQ53_RS12010	COG1609	Transcriptional regulator
LCQ53_RS12025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCQ53_RS12025	COG1263	PTS System
LCQ53_RS12025	COG2190	(PTS) system
LCQ53_RS12030	COG1621	beta-fructofuranosidase activity
LCQ53_RS12040	COG1695	Transcriptional regulator
LCQ53_RS12060	COG2388	GCN5-related N-acetyl-transferase
LCQ53_RS12070	COG3414	Phosphotransferase system galactitol-specific IIB component
LCQ53_RS12075	COG4989	oxidoreductase activity
LCQ53_RS12080	COG3775	system Galactitol-specific IIC component
LCQ53_RS12085	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LCQ53_RS12095	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCQ53_RS12100	COG0371	Dehydrogenase
LCQ53_RS12120	COG0432	Pfam Uncharacterised protein family UPF0047
LCQ53_RS12125	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LCQ53_RS12130	COG2855	membrane
LCQ53_RS12140	COG0583	DNA-binding transcription factor activity
LCQ53_RS12145	COG1960	acyl-CoA dehydrogenase activity
LCQ53_RS12150	COG2086	electron transfer activity
LCQ53_RS12155	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LCQ53_RS12175	COG0673	inositol 2-dehydrogenase activity
LCQ53_RS12190	COG1082	Xylose isomerase domain protein TIM barrel
LCQ53_RS12195	COG1082	Xylose isomerase domain protein TIM barrel
LCQ53_RS12215	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LCQ53_RS12220	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
LCQ53_RS12230	COG0709	Synthesizes selenophosphate from selenide and ATP
LCQ53_RS12240	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LCQ53_RS12245	COG1408	metallophosphoesterase
LCQ53_RS12255	COG1115	amino acid carrier protein
LCQ53_RS12290	COG3906	Belongs to the UPF0473 family
LCQ53_RS12295	COG0475	glutathione-regulated potassium exporter activity
LCQ53_RS12305	COG3608	succinylglutamate desuccinylase aspartoacylase
LCQ53_RS12310	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LCQ53_RS12315	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LCQ53_RS12325	COG0534	Mate efflux family protein
LCQ53_RS12345	COG1349	DNA-binding transcription factor activity
LCQ53_RS12355	COG0673	inositol 2-dehydrogenase activity
LCQ53_RS12360	COG1082	Xylose isomerase domain protein TIM barrel
LCQ53_RS12365	COG1082	Xylose isomerase domain protein TIM barrel
LCQ53_RS12375	COG0561	phosphatase activity
LCQ53_RS12390	COG0456	acetyltransferase
LCQ53_RS12395	COG1773	rubredoxin
LCQ53_RS12395	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LCQ53_RS12400	COG1609	Transcriptional regulator
LCQ53_RS12405	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LCQ53_RS12410	COG3962	Belongs to the TPP enzyme family
LCQ53_RS12430	COG1942	4-Oxalocrotonate Tautomerase
LCQ53_RS12435	COG2086	electron transfer activity
LCQ53_RS12440	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LCQ53_RS12445	COG2610	gluconate transmembrane transporter activity
LCQ53_RS12455	COG1024	Enoyl-CoA hydratase
LCQ53_RS12460	COG1960	acyl-CoA dehydrogenase activity
LCQ53_RS12475	COG1362	aminopeptidase activity
LCQ53_RS12485	COG1151	hydroxylamine reductase activity
LCQ53_RS12490	COG3842	ATPase activity
LCQ53_RS12510	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LCQ53_RS12510	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LCQ53_RS12525	COG0287	Prephenate dehydrogenase
LCQ53_RS12535	COG1649	PFAM Uncharacterised BCR, COG1649
LCQ53_RS12540	COG0740	serine-type endopeptidase activity
LCQ53_RS12555	COG3414	Phosphotransferase system galactitol-specific IIB component
LCQ53_RS12560	COG3775	system Galactitol-specific IIC component
LCQ53_RS12565	COG1063	alcohol dehydrogenase
LCQ53_RS12580	COG1979	alcohol dehydrogenase
LCQ53_RS12590	COG3414	Phosphotransferase system galactitol-specific IIB component
LCQ53_RS12620	COG1528	Iron-storage protein
LCQ53_RS12635	COG3546	catalase activity
LCQ53_RS12640	COG1321	iron dependent repressor
LCQ53_RS12650	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
LCQ53_RS12660	COG0569	domain protein
LCQ53_RS12665	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LCQ53_RS12675	COG0066	3-isopropylmalate dehydratase activity
LCQ53_RS12680	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LCQ53_RS12685	COG0066	3-isopropylmalate dehydratase activity
LCQ53_RS12690	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LCQ53_RS12695	COG2059	Chromate
LCQ53_RS12705	COG0583	DNA-binding transcription factor activity
LCQ53_RS12745	COG0860	N-Acetylmuramoyl-L-alanine amidase
LCQ53_RS12750	COG2267	carboxylic ester hydrolase activity
LCQ53_RS12755	COG2239	Acts as a magnesium transporter
LCQ53_RS12760	COG0726	polysaccharide deacetylase
LCQ53_RS12780	COG1971	Probably functions as a manganese efflux pump
LCQ53_RS12790	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LCQ53_RS12820	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LCQ53_RS12840	COG1739	Uncharacterized protein family UPF0029
LCQ53_RS12845	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LCQ53_RS12865	COG0085	RNA polymerase activity
LCQ53_RS12880	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
LCQ53_RS12885	COG1074	ATP-dependent DNA helicase activity
LCQ53_RS12900	COG0402	S-adenosylhomocysteine deaminase activity
LCQ53_RS12910	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LCQ53_RS12915	COG2022	thiamine diphosphate biosynthetic process
LCQ53_RS12925	COG0352	thiamine-phosphate diphosphorylase activity
LCQ53_RS12935	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LCQ53_RS12940	COG4106	trans-aconitate 2-methyltransferase activity
LCQ53_RS12945	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LCQ53_RS12965	COG0673	inositol 2-dehydrogenase activity
LCQ53_RS12985	COG1191	sigma factor activity
LCQ53_RS13000	COG0006	proline dipeptidase activity
LCQ53_RS13005	COG0205	6-phosphofructokinase activity
LCQ53_RS13010	COG1295	ribonuclease BN
LCQ53_RS13015	COG3711	transcriptional antiterminator
LCQ53_RS13025	COG3715	PTS system
LCQ53_RS13030	COG3716	PTS system mannose fructose sorbose family IID component
LCQ53_RS13040	COG1482	cell wall glycoprotein biosynthetic process
LCQ53_RS13045	COG2190	(PTS) system
LCQ53_RS13045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCQ53_RS13045	COG1263	PTS System
LCQ53_RS13050	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LCQ53_RS13055	COG0800	Aldolase
LCQ53_RS13060	COG3394	polysaccharide catabolic process
LCQ53_RS13065	COG3716	PTS system mannose fructose sorbose family IID component
LCQ53_RS13070	COG3715	PTS system
LCQ53_RS13075	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCQ53_RS13080	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCQ53_RS13090	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LCQ53_RS13095	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LCQ53_RS13095	COG0072	phenylalanine-tRNA ligase activity
LCQ53_RS13110	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LCQ53_RS13120	COG4895	conserved protein (DUF2196)
LCQ53_RS13145	COG0534	Mate efflux family protein
LCQ53_RS13150	COG2081	HI0933 family
LCQ53_RS13155	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LCQ53_RS13165	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LCQ53_RS13170	COG0740	serine-type endopeptidase activity
LCQ53_RS13195	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LCQ53_RS13205	COG1546	Belongs to the CinA family
LCQ53_RS13205	COG1058	Belongs to the CinA family
LCQ53_RS13210	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LCQ53_RS13215	COG2137	regulation of response to DNA damage stimulus
LCQ53_RS13230	COG0488	(ABC) transporter
LCQ53_RS13240	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LCQ53_RS13245	COG0228	four-way junction DNA binding
LCQ53_RS13250	COG1837	Belongs to the UPF0109 family
LCQ53_RS13255	COG0708	Exodeoxyribonuclease III
LCQ53_RS13280	COG1854	S-ribosylhomocysteine lyase activity
LCQ53_RS13330	COG0191	fructose-bisphosphate aldolase activity
LCQ53_RS13340	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCQ53_RS13350	COG3716	PTS system mannose fructose sorbose family IID component
LCQ53_RS13355	COG1063	alcohol dehydrogenase
LCQ53_RS13360	COG2188	Transcriptional regulator
LCQ53_RS13365	COG3711	transcriptional antiterminator
LCQ53_RS13370	COG1263	PTS System
LCQ53_RS13370	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCQ53_RS13370	COG2190	(PTS) system
LCQ53_RS13375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCQ53_RS13375	COG1263	PTS System
LCQ53_RS13380	COG0363	glucosamine-6-phosphate deaminase activity
LCQ53_RS13385	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LCQ53_RS13400	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LCQ53_RS13415	COG0126	phosphoglycerate kinase activity
LCQ53_RS13420	COG0149	triose-phosphate isomerase activity
LCQ53_RS13435	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LCQ53_RS13440	COG0148	phosphopyruvate hydratase activity
LCQ53_RS13455	COG0557	exoribonuclease II activity
LCQ53_RS13460	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LCQ53_RS13470	COG0745	RESPONSE REGULATOR receiver
LCQ53_RS13505	COG2205	protein histidine kinase activity
LCQ53_RS13525	COG0745	RESPONSE REGULATOR receiver
LCQ53_RS13535	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LCQ53_RS13540	COG0336	Belongs to the RNA methyltransferase TrmD family
LCQ53_RS13545	COG0335	large ribosomal subunit rRNA binding
LCQ53_RS13550	COG0681	Belongs to the peptidase S26 family
LCQ53_RS13560	COG0681	Belongs to the peptidase S26 family
LCQ53_RS13565	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LCQ53_RS13570	COG0792	nuclease activity
LCQ53_RS13575	COG1496	oxidoreductase activity
LCQ53_RS13580	COG1160	GTP binding
LCQ53_RS13585	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LCQ53_RS13595	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LCQ53_RS13600	COG0534	Mate efflux family protein
LCQ53_RS13605	COG1263	PTS System
LCQ53_RS13605	COG2190	(PTS) system
LCQ53_RS13605	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCQ53_RS13620	COG2207	Transcriptional regulator
LCQ53_RS13640	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LCQ53_RS13645	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LCQ53_RS13650	COG2357	RelA SpoT domain protein
LCQ53_RS13655	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LCQ53_RS13655	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
LCQ53_RS13660	COG1187	pseudouridine synthase activity
LCQ53_RS13665	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LCQ53_RS13670	COG1028	Short-chain dehydrogenase reductase Sdr
LCQ53_RS13675	COG0564	pseudouridine synthase activity
LCQ53_RS13680	COG3331	DNA recombination
LCQ53_RS13685	COG1561	YicC-like family, N-terminal region
LCQ53_RS13690	COG0194	GDP metabolic process
LCQ53_RS13695	COG1758	RNA polymerase activity
LCQ53_RS13700	COG1968	undecaprenyl-diphosphatase activity
LCQ53_RS13710	COG0232	Belongs to the dGTPase family. Type 2 subfamily
LCQ53_RS13715	COG0358	DNA primase activity
LCQ53_RS13720	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LCQ53_RS13725	COG2384	SAM-dependent methyltransferase
LCQ53_RS13770	COG3773	Cell wall hydrolase
LCQ53_RS13770	COG3409	Peptidoglycan-binding domain 1 protein
LCQ53_RS13785	COG1122	ATPase activity
LCQ53_RS13790	COG3645	SOS response
LCQ53_RS13800	COG0583	DNA-binding transcription factor activity
LCQ53_RS13805	COG3620	sequence-specific DNA binding
LCQ53_RS13810	COG0720	synthase
LCQ53_RS13815	COG0602	queuosine metabolic process
LCQ53_RS13820	COG0302	gtp cyclohydrolase
LCQ53_RS13835	COG1733	regulation of RNA biosynthetic process
LCQ53_RS13840	COG1335	isochorismatase
LCQ53_RS13845	COG1733	regulation of RNA biosynthetic process
LCQ53_RS13855	COG0069	glutamate synthase activity
LCQ53_RS13855	COG0070	glutamate synthase
LCQ53_RS13855	COG0067	glutamate synthase
LCQ53_RS13860	COG0493	'glutamate synthase
LCQ53_RS13905	COG0628	permease
LCQ53_RS13920	COG0028	Belongs to the TPP enzyme family
LCQ53_RS13930	COG1959	2 iron, 2 sulfur cluster binding
LCQ53_RS13935	COG0534	Mate efflux family protein
LCQ53_RS13945	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LCQ53_RS13945	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LCQ53_RS13950	COG0237	dephospho-CoA kinase activity
LCQ53_RS13955	COG0456	acetyltransferase
LCQ53_RS13965	COG1595	DNA-templated transcription, initiation
LCQ53_RS13970	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LCQ53_RS13985	COG2195	Cleaves the N-terminal amino acid of tripeptides
LCQ53_RS13990	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LCQ53_RS14020	COG0443	Heat shock 70 kDa protein
LCQ53_RS14025	COG1420	regulation of RNA biosynthetic process
LCQ53_RS14030	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LCQ53_RS14035	COG0443	Heat shock 70 kDa protein
LCQ53_RS14040	COG0484	heat shock protein binding
LCQ53_RS14045	COG0561	phosphatase activity
LCQ53_RS14075	COG3263	regulation of cellular component size
LCQ53_RS14085	COG2264	protein methyltransferase activity
LCQ53_RS14090	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LCQ53_RS14095	COG1104	cysteine desulfurase activity
LCQ53_RS14110	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LCQ53_RS14115	COG4472	Bacterial protein of unknown function (DUF965)
LCQ53_RS14120	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LCQ53_RS14130	COG0735	belongs to the Fur family
LCQ53_RS14135	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LCQ53_RS14145	COG4122	O-methyltransferase activity
LCQ53_RS14150	COG0826	peptidase U32
LCQ53_RS14170	COG1309	transcriptional regulator
LCQ53_RS14185	COG0745	RESPONSE REGULATOR receiver
LCQ53_RS14190	COG5002	protein histidine kinase activity
LCQ53_RS14200	COG1876	peptidase activity
LCQ53_RS14235	COG2226	methyltransferase
LCQ53_RS14250	COG0346	lactoylglutathione lyase activity
LCQ53_RS14260	COG0583	DNA-binding transcription factor activity
LCQ53_RS14270	COG2814	Major facilitator Superfamily
LCQ53_RS14285	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LCQ53_RS14285	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
LCQ53_RS14290	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
LCQ53_RS14300	COG1917	Cupin 2, conserved barrel domain protein
LCQ53_RS14300	COG2207	Transcriptional regulator
LCQ53_RS14305	COG2271	Major facilitator Superfamily
LCQ53_RS14310	COG4670	ketone body catabolic process
LCQ53_RS14315	COG2030	dehydratase
LCQ53_RS14320	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LCQ53_RS14330	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LCQ53_RS14335	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LCQ53_RS14345	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
LCQ53_RS14350	COG3428	Bacterial PH domain
LCQ53_RS14355	COG3428	Bacterial PH domain
LCQ53_RS14365	COG0583	DNA-binding transcription factor activity
LCQ53_RS14370	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LCQ53_RS14375	COG1979	alcohol dehydrogenase
LCQ53_RS14390	COG3854	ATPases associated with a variety of cellular activities
LCQ53_RS14430	COG1302	Protein conserved in bacteria
LCQ53_RS14435	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LCQ53_RS14440	COG1570	exodeoxyribonuclease VII activity
LCQ53_RS14445	COG1722	exodeoxyribonuclease VII activity
LCQ53_RS14455	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LCQ53_RS14460	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
LCQ53_RS14465	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LCQ53_RS14470	COG1438	arginine binding
LCQ53_RS14475	COG0497	DNA recombination
LCQ53_RS14480	COG0750	zinc metalloprotease
LCQ53_RS14485	COG0745	RESPONSE REGULATOR receiver
LCQ53_RS14490	COG0745	RESPONSE REGULATOR receiver
LCQ53_RS14495	COG1293	RNA-binding protein homologous to eukaryotic snRNP
LCQ53_RS14505	COG0124	histidyl-tRNA synthetase
LCQ53_RS14510	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LCQ53_RS14515	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LCQ53_RS14520	COG0131	Imidazoleglycerol-phosphate dehydratase
LCQ53_RS14535	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LCQ53_RS14550	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LCQ53_RS14565	COG1702	phosphate starvation-inducible protein PhoH
LCQ53_RS14590	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
LCQ53_RS14595	COG2081	HI0933 family
LCQ53_RS14600	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
LCQ53_RS14605	COG1328	CTP reductase activity
LCQ53_RS14610	COG0602	queuosine metabolic process
LCQ53_RS14615	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LCQ53_RS14620	COG4224	UPF0291 protein
LCQ53_RS14630	COG4656	Part of a membrane complex involved in electron transport
LCQ53_RS14635	COG4658	electron transport chain
LCQ53_RS14640	COG4659	FMN binding
LCQ53_RS14645	COG4660	Part of a membrane complex involved in electron transport
LCQ53_RS14650	COG4657	Part of a membrane complex involved in electron transport
LCQ53_RS14655	COG2878	Part of a membrane complex involved in electron transport
LCQ53_RS14660	COG1873	PFAM PRC-barrel domain
LCQ53_RS14665	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LCQ53_RS14670	COG0606	chelatase, subunit chli
LCQ53_RS14675	COG0758	DNA mediated transformation
LCQ53_RS14680	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LCQ53_RS14690	COG0052	Belongs to the universal ribosomal protein uS2 family
LCQ53_RS14695	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LCQ53_RS14700	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LCQ53_RS14710	COG2226	methyltransferase
LCQ53_RS14720	COG3447	MASE1 domain protein
LCQ53_RS14720	COG5001	Diguanylate cyclase
LCQ53_RS14720	COG5002	protein histidine kinase activity
LCQ53_RS14725	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LCQ53_RS14730	COG0519	Catalyzes the synthesis of GMP from XMP
LCQ53_RS14735	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCQ53_RS14750	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LCQ53_RS14785	COG5002	protein histidine kinase activity
LCQ53_RS14785	COG5001	Diguanylate cyclase
LCQ53_RS14785	COG3447	MASE1 domain protein
LCQ53_RS14790	COG5001	Diguanylate cyclase
LCQ53_RS14790	COG3300	MHYT domain
LCQ53_RS14795	COG0784	Response regulator, receiver
LCQ53_RS14795	COG2205	protein histidine kinase activity
LCQ53_RS14795	COG5002	protein histidine kinase activity
LCQ53_RS14800	COG0561	phosphatase activity
LCQ53_RS14845	COG1122	ATPase activity
LCQ53_RS14855	COG0135	phosphoribosylanthranilate isomerase activity
LCQ53_RS14860	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LCQ53_RS14865	COG1957	nucleoside hydrolase
LCQ53_RS14875	COG1979	alcohol dehydrogenase
LCQ53_RS14880	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LCQ53_RS14895	COG1349	DNA-binding transcription factor activity
LCQ53_RS14900	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LCQ53_RS14905	COG1882	Formate acetyltransferase
LCQ53_RS14915	COG0673	inositol 2-dehydrogenase activity
LCQ53_RS14920	COG4702	Belongs to the UPF0303 family
LCQ53_RS14925	COG0745	RESPONSE REGULATOR receiver
LCQ53_RS14950	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
LCQ53_RS14970	COG3711	transcriptional antiterminator
LCQ53_RS14975	COG0246	Mannitol dehydrogenase
LCQ53_RS14980	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
LCQ53_RS14985	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LCQ53_RS14990	COG1979	alcohol dehydrogenase
LCQ53_RS15020	COG1063	alcohol dehydrogenase
LCQ53_RS15025	COG3414	Phosphotransferase system galactitol-specific IIB component
LCQ53_RS15030	COG3775	system Galactitol-specific IIC component
LCQ53_RS15040	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LCQ53_RS15040	COG3711	transcriptional antiterminator
LCQ53_RS15045	COG3620	sequence-specific DNA binding
LCQ53_RS15060	COG0640	Transcriptional regulator
LCQ53_RS15070	COG2217	Heavy metal translocating P-type atpase
LCQ53_RS15090	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LCQ53_RS15100	COG0181	hydroxymethylbilane synthase activity
LCQ53_RS15105	COG0113	porphobilinogen synthase activity
LCQ53_RS15110	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LCQ53_RS15115	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
LCQ53_RS15150	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
LCQ53_RS15160	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
LCQ53_RS15180	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LCQ53_RS15205	COG1309	transcriptional regulator
LCQ53_RS15210	COG0534	Mate efflux family protein
LCQ53_RS15215	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LCQ53_RS15225	COG5566	PFAM Mor transcription activator
LCQ53_RS15260	COG2205	protein histidine kinase activity
LCQ53_RS15265	COG1136	(ABC) transporter
LCQ53_RS15265	COG0577	efflux transmembrane transporter activity
LCQ53_RS15285	COG1309	transcriptional regulator
LCQ53_RS15310	COG0534	Mate efflux family protein
LCQ53_RS15320	COG1122	ATPase activity
LCQ53_RS15335	COG0310	cobalt ion transport
LCQ53_RS15365	COG1011	Hydrolase
LCQ53_RS15380	COG1269	ATP hydrolysis coupled proton transport
LCQ53_RS15400	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
LCQ53_RS15410	COG1394	ATPase activity, coupled to movement of substances
LCQ53_RS15420	COG1012	belongs to the aldehyde dehydrogenase family
LCQ53_RS15430	COG0426	domain, Protein
LCQ53_RS15450	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LCQ53_RS15455	COG0402	S-adenosylhomocysteine deaminase activity
LCQ53_RS15460	COG1490	D-aminoacyl-tRNA deacylase activity
LCQ53_RS15465	COG0528	UMP kinase activity
LCQ53_RS15470	COG0233	cytoplasmic translational termination
LCQ53_RS15480	COG4589	Belongs to the CDS family
LCQ53_RS15485	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
LCQ53_RS15490	COG0750	zinc metalloprotease
LCQ53_RS15495	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LCQ53_RS15505	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
LCQ53_RS15505	COG2199	diguanylate cyclase activity
LCQ53_RS15515	COG1937	Protein conserved in bacteria
LCQ53_RS15530	COG1121	(ABC) transporter
LCQ53_RS15535	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LCQ53_RS15550	COG0779	Required for maturation of 30S ribosomal subunits
LCQ53_RS15555	COG0195	Participates in both transcription termination and antitermination
LCQ53_RS15560	COG2740	Nucleic-acid-binding protein implicated in transcription termination
LCQ53_RS15570	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LCQ53_RS15575	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LCQ53_RS15580	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LCQ53_RS15585	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LCQ53_RS15590	COG0196	riboflavin kinase activity
LCQ53_RS15610	COG1304	FMN binding
LCQ53_RS15620	COG5002	protein histidine kinase activity
LCQ53_RS15620	COG2205	protein histidine kinase activity
LCQ53_RS15620	COG0784	Response regulator, receiver
LCQ53_RS15625	COG4974	Belongs to the 'phage' integrase family
LCQ53_RS15655	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LCQ53_RS15675	COG0037	tRNA processing
LCQ53_RS15685	COG3177	Filamentation induced by cAMP protein fic
LCQ53_RS15690	COG0789	Transcriptional regulator
LCQ53_RS15740	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LCQ53_RS15745	COG0187	DNA topoisomerase II activity
LCQ53_RS15750	COG2199	diguanylate cyclase activity
LCQ53_RS15750	COG2200	EAL domain
LCQ53_RS15750	COG2202	Pas domain
LCQ53_RS15770	COG2155	Conserved Protein
LCQ53_RS15790	COG1533	DNA photolyase activity
LCQ53_RS15800	COG1473	amidohydrolase
LCQ53_RS15805	COG1473	amidohydrolase
LCQ53_RS15860	COG1131	(ABC) transporter
LCQ53_RS15865	COG0789	Transcriptional regulator
LCQ53_RS15895	COG2378	regulation of single-species biofilm formation
LCQ53_RS15920	COG1979	alcohol dehydrogenase
LCQ53_RS15930	COG3716	PTS system mannose fructose sorbose family IID component
LCQ53_RS15935	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LCQ53_RS15940	COG1063	alcohol dehydrogenase
LCQ53_RS15950	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
LCQ53_RS15960	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LCQ53_RS15965	COG0551	DNA topoisomerase type I activity
LCQ53_RS15965	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LCQ53_RS15975	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LCQ53_RS15980	COG3706	GGDEF domain
LCQ53_RS15990	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LCQ53_RS15995	COG0527	aspartate kinase activity
LCQ53_RS16000	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LCQ53_RS16010	COG0277	FAD linked oxidase domain protein
LCQ53_RS16020	COG2086	electron transfer activity
LCQ53_RS16025	COG2186	Transcriptional regulator
LCQ53_RS16030	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LCQ53_RS16050	COG3875	lactate racemase activity
LCQ53_RS16055	COG1620	l-lactate permease
LCQ53_RS16060	COG0124	histidyl-tRNA synthetase
LCQ53_RS16070	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LCQ53_RS16075	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LCQ53_RS16080	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LCQ53_RS16090	COG0540	Belongs to the ATCase OTCase family
LCQ53_RS16100	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LCQ53_RS16110	COG4968	Prepilin-type N-terminal cleavage methylation domain
LCQ53_RS16115	COG1408	metallophosphoesterase
LCQ53_RS16130	COG1733	regulation of RNA biosynthetic process
LCQ53_RS16140	COG0232	Belongs to the dGTPase family. Type 2 subfamily
LCQ53_RS16145	COG0232	Belongs to the dGTPase family. Type 2 subfamily
LCQ53_RS16180	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LCQ53_RS16185	COG0745	RESPONSE REGULATOR receiver
LCQ53_RS16230	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LCQ53_RS16245	COG1459	type II secretion system
LCQ53_RS16250	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LCQ53_RS16305	COG5002	protein histidine kinase activity
LCQ53_RS16320	COG0745	RESPONSE REGULATOR receiver
LCQ53_RS16325	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LCQ53_RS16330	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LCQ53_RS16335	COG2738	Putative neutral zinc metallopeptidase
LCQ53_RS16345	COG0217	transcriptional regulatory protein
LCQ53_RS16350	COG1253	flavin adenine dinucleotide binding
LCQ53_RS16355	COG2337	Toxic component of a toxin-antitoxin (TA) module
LCQ53_RS16360	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LCQ53_RS16365	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LCQ53_RS16365	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LCQ53_RS16370	COG0736	holo-[acyl-carrier-protein] synthase activity
LCQ53_RS16375	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LCQ53_RS16380	COG0488	(ABC) transporter
LCQ53_RS16385	COG1215	transferase activity, transferring glycosyl groups
LCQ53_RS16390	COG0789	Transcriptional regulator
LCQ53_RS16395	COG1131	(ABC) transporter
LCQ53_RS16405	COG1404	Belongs to the peptidase S8 family
LCQ53_RS16410	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LCQ53_RS16415	COG0481	GTPase activity
LCQ53_RS16425	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
LCQ53_RS16430	COG0268	Binds directly to 16S ribosomal RNA
LCQ53_RS16440	COG0583	DNA-binding transcription factor activity
LCQ53_RS16445	COG2068	MobA-Related Protein
LCQ53_RS16450	COG0658	competence protein
LCQ53_RS16450	COG2333	competence protein COMEC
LCQ53_RS16465	COG0745	RESPONSE REGULATOR receiver
LCQ53_RS16480	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LCQ53_RS16485	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LCQ53_RS16490	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LCQ53_RS16495	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LCQ53_RS16500	COG0137	argininosuccinate synthase activity
LCQ53_RS16505	COG2949	membrane
LCQ53_RS16510	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LCQ53_RS16510	COG0551	DNA topoisomerase type I activity
LCQ53_RS16515	COG0666	response to abiotic stimulus
LCQ53_RS16515	COG3177	Filamentation induced by cAMP protein fic
LCQ53_RS16525	COG0165	Argininosuccinate lyase
LCQ53_RS16535	COG2226	methyltransferase
LCQ53_RS16555	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LCQ53_RS16560	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LCQ53_RS16565	COG0028	Belongs to the TPP enzyme family
LCQ53_RS16570	COG0129	dihydroxy-acid dehydratase activity
LCQ53_RS16575	COG0473	3-isopropylmalate dehydrogenase activity
LCQ53_RS16590	COG0860	N-Acetylmuramoyl-L-alanine amidase
LCQ53_RS16595	COG0860	N-Acetylmuramoyl-L-alanine amidase
LCQ53_RS16605	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LCQ53_RS16645	COG0698	ribose 5-phosphate isomerase