locus-tag	class	description
CPRO_RS00015	COG0592	DNA-directed DNA polymerase activity
CPRO_RS00025	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CPRO_RS00030	COG0187	DNA topoisomerase II activity
CPRO_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CPRO_RS00060	COG1597	lipid kinase activity
CPRO_RS00065	COG1192	Involved in chromosome partitioning
CPRO_RS00070	COG1475	DNA binding
CPRO_RS00080	COG0561	phosphatase activity
CPRO_RS00085	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CPRO_RS00095	COG2076	Multidrug Resistance protein
CPRO_RS00105	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CPRO_RS00115	COG1609	Transcriptional regulator
CPRO_RS00125	COG2033	superoxide reductase activity
CPRO_RS00130	COG0426	domain, Protein
CPRO_RS00135	COG1592	Rubrerythrin
CPRO_RS00140	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CPRO_RS00150	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CPRO_RS00155	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CPRO_RS00160	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CPRO_RS00165	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CPRO_RS00170	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CPRO_RS00175	COG4989	oxidoreductase activity
CPRO_RS00190	COG0017	Asparaginyl-tRNA synthetase
CPRO_RS00195	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CPRO_RS00195	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CPRO_RS00200	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CPRO_RS00205	COG0733	neurotransmitter:sodium symporter activity
CPRO_RS00215	COG1115	amino acid carrier protein
CPRO_RS00235	COG0516	GMP reductase activity
CPRO_RS00235	COG0517	IMP dehydrogenase activity
CPRO_RS00255	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CPRO_RS00260	COG2183	response to ionizing radiation
CPRO_RS00290	COG0629	single-stranded DNA binding
CPRO_RS00295	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CPRO_RS00300	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CPRO_RS00310	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CPRO_RS00320	COG3118	belongs to the thioredoxin family
CPRO_RS00325	COG1620	l-lactate permease
CPRO_RS00330	COG0039	L-malate dehydrogenase activity
CPRO_RS00340	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CPRO_RS00345	COG2002	toxin-antitoxin pair type II binding
CPRO_RS00355	COG0700	Nucleoside recognition
CPRO_RS00365	COG0590	tRNA wobble adenosine to inosine editing
CPRO_RS00380	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CPRO_RS00385	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CPRO_RS00390	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CPRO_RS00405	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CPRO_RS00410	COG1116	anion transmembrane transporter activity
CPRO_RS00415	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CPRO_RS00420	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CPRO_RS00450	COG0697	spore germination
CPRO_RS00475	COG1803	Methylglyoxal synthase
CPRO_RS00480	COG0772	Belongs to the SEDS family
CPRO_RS00485	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CPRO_RS00490	COG2894	cell division
CPRO_RS00495	COG0850	regulation of cytokinetic process
CPRO_RS00500	COG0768	penicillin binding
CPRO_RS00515	COG1077	Cell shape determining protein MreB Mrl
CPRO_RS00525	COG1245	4Fe-4S binding domain
CPRO_RS00525	COG2878	Part of a membrane complex involved in electron transport
CPRO_RS00530	COG4657	Part of a membrane complex involved in electron transport
CPRO_RS00535	COG4660	Part of a membrane complex involved in electron transport
CPRO_RS00545	COG4658	electron transport chain
CPRO_RS00550	COG4656	Part of a membrane complex involved in electron transport
CPRO_RS00555	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CPRO_RS00570	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CPRO_RS00580	COG1114	Component of the transport system for branched-chain amino acids
CPRO_RS00595	COG1404	Belongs to the peptidase S8 family
CPRO_RS00610	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CPRO_RS00625	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CPRO_RS00635	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CPRO_RS00640	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CPRO_RS00640	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CPRO_RS00665	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CPRO_RS00670	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CPRO_RS00680	COG0358	DNA primase activity
CPRO_RS00685	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CPRO_RS00690	COG2384	SAM-dependent methyltransferase
CPRO_RS00695	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CPRO_RS00700	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CPRO_RS00720	COG0582	viral genome integration into host DNA
CPRO_RS00775	COG4974	Belongs to the 'phage' integrase family
CPRO_RS00790	COG0288	reversible hydration of carbon dioxide
CPRO_RS00810	COG0628	permease
CPRO_RS00815	COG3275	phosphorelay sensor kinase activity
CPRO_RS00820	COG3279	Response regulator of the LytR AlgR family
CPRO_RS00825	COG1966	Carbon starvation protein
CPRO_RS00840	COG0813	purine-nucleoside phosphorylase activity
CPRO_RS00845	COG1757	Na H antiporter
CPRO_RS00860	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CPRO_RS00865	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CPRO_RS00870	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CPRO_RS00880	COG3842	ATPase activity
CPRO_RS00890	COG0681	Belongs to the peptidase S26 family
CPRO_RS00915	COG0488	(ABC) transporter
CPRO_RS00920	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CPRO_RS00930	COG0534	Mate efflux family protein
CPRO_RS00935	COG0789	Transcriptional regulator
CPRO_RS00970	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CPRO_RS00980	COG0617	tRNA 3'-terminal CCA addition
CPRO_RS01000	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CPRO_RS01005	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CPRO_RS01010	COG1309	transcriptional regulator
CPRO_RS01045	COG0730	response to heat
CPRO_RS01055	COG1640	4-alpha-glucanotransferase
CPRO_RS01060	COG0367	asparagine synthase
CPRO_RS01080	COG0012	GTP binding
CPRO_RS01105	COG2385	sporulation resulting in formation of a cellular spore
CPRO_RS01120	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CPRO_RS01135	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CPRO_RS01140	COG0569	domain protein
CPRO_RS01145	COG0653	protein targeting
CPRO_RS01155	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CPRO_RS01165	COG1213	nucleotidyl transferase
CPRO_RS01175	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CPRO_RS01185	COG0301	tRNA thio-modification
CPRO_RS01200	COG3584	3D domain protein
CPRO_RS01200	COG1388	LysM domain
CPRO_RS01205	COG0084	hydrolase, TatD family'
CPRO_RS01210	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CPRO_RS01210	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CPRO_RS01230	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CPRO_RS01240	COG0840	transmembrane signaling receptor activity
CPRO_RS01245	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
CPRO_RS01255	COG0659	secondary active sulfate transmembrane transporter activity
CPRO_RS01260	COG1079	Belongs to the binding-protein-dependent transport system permease family
CPRO_RS01265	COG4603	Belongs to the binding-protein-dependent transport system permease family
CPRO_RS01270	COG3845	ABC transporter
CPRO_RS01280	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CPRO_RS01295	COG0534	Mate efflux family protein
CPRO_RS01300	COG2861	carbohydrate metabolic process
CPRO_RS01305	COG3331	DNA recombination
CPRO_RS01310	COG0312	modulator of DNA gyrase
CPRO_RS01315	COG0312	modulator of DNA gyrase
CPRO_RS01320	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CPRO_RS01325	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CPRO_RS01330	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CPRO_RS01335	COG1610	YqeY-like protein
CPRO_RS01350	COG1122	ATPase activity
CPRO_RS01365	COG1702	phosphate starvation-inducible protein PhoH
CPRO_RS01370	COG1480	7TM receptor with intracellular HD hydrolase
CPRO_RS01375	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CPRO_RS01380	COG0295	cytidine deaminase activity
CPRO_RS01385	COG1573	uracil-dna glycosylase
CPRO_RS01395	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CPRO_RS01400	COG1381	Involved in DNA repair and RecF pathway recombination
CPRO_RS01405	COG0423	glycine-tRNA ligase activity
CPRO_RS01415	COG0574	Belongs to the PEP-utilizing enzyme family
CPRO_RS01415	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CPRO_RS01430	COG1677	Flagellar hook-basal body complex protein FliE
CPRO_RS01440	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CPRO_RS01450	COG1157	protein secretion by the type III secretion system
CPRO_RS01470	COG2358	TRAP transporter, solute receptor (TAXI family
CPRO_RS01485	COG0789	Transcriptional regulator
CPRO_RS01515	COG0156	8-amino-7-oxononanoate synthase activity
CPRO_RS01525	COG0840	transmembrane signaling receptor activity
CPRO_RS01535	COG0735	belongs to the Fur family
CPRO_RS01545	COG1215	transferase activity, transferring glycosyl groups
CPRO_RS01590	COG1074	ATP-dependent DNA helicase activity
CPRO_RS01605	COG1309	transcriptional regulator
CPRO_RS01625	COG0802	atpase or kinase
CPRO_RS01630	COG1214	PFAM Peptidase M22, glycoprotease
CPRO_RS01635	COG0456	acetyltransferase
CPRO_RS01640	COG1067	ATP-dependent peptidase activity
CPRO_RS01650	COG0860	N-Acetylmuramoyl-L-alanine amidase
CPRO_RS01650	COG2247	cell wall binding repeat
CPRO_RS01660	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CPRO_RS01715	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CPRO_RS01720	COG1164	Oligoendopeptidase f
CPRO_RS01725	COG0297	glycogen (starch) synthase activity
CPRO_RS01775	COG1584	GPR1 FUN34 yaaH family protein
CPRO_RS01785	COG3620	sequence-specific DNA binding
CPRO_RS01795	COG0640	Transcriptional regulator
CPRO_RS01815	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CPRO_RS01850	COG1131	(ABC) transporter
CPRO_RS01860	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CPRO_RS01860	COG1918	ferrous iron import across plasma membrane
CPRO_RS01865	COG1396	sequence-specific DNA binding
CPRO_RS01875	COG2340	Cysteine-rich secretory protein family
CPRO_RS01905	COG0544	peptidyl-prolyl cis-trans isomerase activity
CPRO_RS01915	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CPRO_RS01925	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CPRO_RS01940	COG1674	ftsk spoiiie
CPRO_RS01945	COG2759	Belongs to the formate--tetrahydrofolate ligase family
CPRO_RS01955	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CPRO_RS01970	COG1546	Belongs to the CinA family
CPRO_RS01970	COG1058	Belongs to the CinA family
CPRO_RS01980	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CPRO_RS01985	COG2137	regulation of response to DNA damage stimulus
CPRO_RS02000	COG2868	ribosomal protein
CPRO_RS02005	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CPRO_RS02010	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CPRO_RS02015	COG2199	diguanylate cyclase activity
CPRO_RS02025	COG0612	Peptidase, M16
CPRO_RS02030	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CPRO_RS02035	COG0488	(ABC) transporter
CPRO_RS02040	COG1253	flavin adenine dinucleotide binding
CPRO_RS02045	COG1388	LysM domain
CPRO_RS02045	COG3858	chitin binding
CPRO_RS02055	COG0745	RESPONSE REGULATOR receiver
CPRO_RS02060	COG3850	Histidine kinase
CPRO_RS02060	COG5002	protein histidine kinase activity
CPRO_RS02080	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CPRO_RS02090	COG0037	tRNA processing
CPRO_RS02095	COG4974	Belongs to the 'phage' integrase family
CPRO_RS02120	COG0335	large ribosomal subunit rRNA binding
CPRO_RS02145	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CPRO_RS02150	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
CPRO_RS02150	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CPRO_RS02160	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CPRO_RS02165	COG1490	D-aminoacyl-tRNA deacylase activity
CPRO_RS02170	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CPRO_RS02175	COG0124	histidyl-tRNA synthetase
CPRO_RS02180	COG0569	domain protein
CPRO_RS02195	COG0481	GTPase activity
CPRO_RS02200	COG0745	RESPONSE REGULATOR receiver
CPRO_RS02205	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CPRO_RS02230	COG0693	protein deglycase activity
CPRO_RS02250	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CPRO_RS02260	COG1242	4 iron, 4 sulfur cluster binding
CPRO_RS02270	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CPRO_RS02280	COG4492	Belongs to the UPF0735 family
CPRO_RS02285	COG0083	homoserine kinase activity
CPRO_RS02295	COG3546	catalase activity
CPRO_RS02315	COG1335	isochorismatase
CPRO_RS02335	COG1268	BioY protein
CPRO_RS02345	COG1960	acyl-CoA dehydrogenase activity
CPRO_RS02350	COG2086	electron transfer activity
CPRO_RS02355	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CPRO_RS02360	COG2357	RelA SpoT domain protein
CPRO_RS02375	COG0557	exoribonuclease II activity
CPRO_RS02385	COG0531	amino acid
CPRO_RS02390	COG1342	Belongs to the UPF0251 family
CPRO_RS02400	COG1115	amino acid carrier protein
CPRO_RS02405	COG1115	amino acid carrier protein
CPRO_RS02410	COG1115	amino acid carrier protein
CPRO_RS02420	COG0438	transferase activity, transferring glycosyl groups
CPRO_RS02425	COG0210	DNA helicase
CPRO_RS02435	COG1131	(ABC) transporter
CPRO_RS02460	COG2720	vancomycin resistance protein
CPRO_RS02470	COG0436	Aminotransferase
CPRO_RS02475	COG1253	flavin adenine dinucleotide binding
CPRO_RS02480	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CPRO_RS02495	COG1695	Transcriptional regulator
CPRO_RS02535	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CPRO_RS02535	COG1918	ferrous iron import across plasma membrane
CPRO_RS02545	COG0840	transmembrane signaling receptor activity
CPRO_RS02550	COG0716	FMN binding
CPRO_RS02570	COG2357	RelA SpoT domain protein
CPRO_RS02590	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CPRO_RS02590	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
CPRO_RS02600	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CPRO_RS02605	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CPRO_RS02620	COG2848	UPF0210 protein
CPRO_RS02630	COG0051	transcription antitermination factor activity, RNA binding
CPRO_RS02640	COG0088	Forms part of the polypeptide exit tunnel
CPRO_RS02645	COG0089	rRNA binding
CPRO_RS02650	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CPRO_RS02660	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CPRO_RS02670	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CPRO_RS02675	COG0255	Belongs to the universal ribosomal protein uL29 family
CPRO_RS02680	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CPRO_RS02685	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CPRO_RS02690	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CPRO_RS02695	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CPRO_RS02700	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CPRO_RS02705	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CPRO_RS02710	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CPRO_RS02720	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CPRO_RS02730	COG0200	Binds to the 23S rRNA
CPRO_RS02735	COG0201	protein transport
CPRO_RS02740	COG0563	adenylate kinase activity
CPRO_RS02755	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CPRO_RS02765	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CPRO_RS02770	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CPRO_RS02780	COG0202	RNA polymerase activity
CPRO_RS02785	COG0203	ribosomal protein L17
CPRO_RS02800	COG1122	ATPase activity
CPRO_RS02810	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CPRO_RS02815	COG0101	tRNA pseudouridine synthase activity
CPRO_RS02820	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CPRO_RS02825	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CPRO_RS02830	COG5505	Protein of unknown function (DUF819)
CPRO_RS02845	COG1534	Rna-binding protein
CPRO_RS02860	COG0799	negative regulation of ribosome biogenesis
CPRO_RS02865	COG0067	glutamate synthase
CPRO_RS02865	COG0069	glutamate synthase activity
CPRO_RS02865	COG0070	glutamate synthase
CPRO_RS02870	COG0493	'glutamate synthase
CPRO_RS02875	COG0840	transmembrane signaling receptor activity
CPRO_RS02885	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CPRO_RS02905	COG1098	S1 RNA binding domain
CPRO_RS02915	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CPRO_RS02920	COG2011	ABC-type metal ion transport system permease component
CPRO_RS02930	COG1473	amidohydrolase
CPRO_RS02935	COG0534	Mate efflux family protein
CPRO_RS02945	COG0191	fructose-bisphosphate aldolase activity
CPRO_RS02950	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CPRO_RS02960	COG0251	oxidation-reduction process
CPRO_RS02980	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CPRO_RS02985	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CPRO_RS02995	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CPRO_RS03000	COG0131	Imidazoleglycerol-phosphate dehydratase
CPRO_RS03005	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CPRO_RS03015	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CPRO_RS03020	COG0107	imidazoleglycerol-phosphate synthase activity
CPRO_RS03025	COG0140	phosphoribosyl-ATP diphosphatase activity
CPRO_RS03025	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CPRO_RS03035	COG0386	Belongs to the glutathione peroxidase family
CPRO_RS03040	COG1846	Transcriptional regulator
CPRO_RS03115	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CPRO_RS03125	COG2205	protein histidine kinase activity
CPRO_RS03130	COG0745	RESPONSE REGULATOR receiver
CPRO_RS03170	COG0626	cystathionine gamma-synthase activity
CPRO_RS03175	COG0583	DNA-binding transcription factor activity
CPRO_RS03195	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CPRO_RS03210	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CPRO_RS03220	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CPRO_RS03225	COG0511	ligase activity, forming carbon-carbon bonds
CPRO_RS03235	COG0439	Biotin carboxylase
CPRO_RS03260	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CPRO_RS03265	COG0268	Binds directly to 16S ribosomal RNA
CPRO_RS03275	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CPRO_RS03280	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
CPRO_RS03285	COG1247	-acetyltransferase
CPRO_RS03290	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CPRO_RS03295	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CPRO_RS03305	COG0785	Cytochrome C biogenesis protein
CPRO_RS03320	COG0789	Transcriptional regulator
CPRO_RS03320	COG4978	Transcriptional regulator
CPRO_RS03330	COG1607	acyl-coa hydrolase
CPRO_RS03340	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CPRO_RS03360	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CPRO_RS03365	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CPRO_RS03385	COG1940	carbohydrate kinase activity
CPRO_RS03395	COG0427	acetyl-CoA hydrolase
CPRO_RS03400	COG0590	tRNA wobble adenosine to inosine editing
CPRO_RS03410	COG0632	four-way junction helicase activity
CPRO_RS03415	COG2255	four-way junction helicase activity
CPRO_RS03430	COG1592	Rubrerythrin
CPRO_RS03435	COG1489	DNA binding
CPRO_RS03440	COG1686	Belongs to the peptidase S11 family
CPRO_RS03445	COG2199	diguanylate cyclase activity
CPRO_RS03470	COG0475	glutathione-regulated potassium exporter activity
CPRO_RS03500	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CPRO_RS03505	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CPRO_RS03510	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CPRO_RS03525	COG2226	methyltransferase
CPRO_RS03530	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CPRO_RS03545	COG1269	ATP hydrolysis coupled proton transport
CPRO_RS03550	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CPRO_RS03555	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
CPRO_RS03570	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
CPRO_RS03575	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
CPRO_RS03580	COG1394	ATPase activity, coupled to movement of substances
CPRO_RS03585	COG0436	Aminotransferase
CPRO_RS03595	COG2267	carboxylic ester hydrolase activity
CPRO_RS03600	COG2502	aspartate--ammonia ligase
CPRO_RS03615	COG2385	sporulation resulting in formation of a cellular spore
CPRO_RS03615	COG2247	cell wall binding repeat
CPRO_RS03620	COG0028	Belongs to the TPP enzyme family
CPRO_RS03625	COG0440	acetolactate synthase activity
CPRO_RS03630	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CPRO_RS03640	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CPRO_RS03650	COG0582	viral genome integration into host DNA
CPRO_RS03745	COG1278	Cold shock
CPRO_RS03760	COG3728	DNA packaging
CPRO_RS03905	COG0737	Belongs to the 5'-nucleotidase family
CPRO_RS03910	COG0737	Belongs to the 5'-nucleotidase family
CPRO_RS03935	COG2894	cell division
CPRO_RS03945	COG3191	aminopeptidase activity
CPRO_RS03950	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CPRO_RS03960	COG3879	Bacterial protein of unknown function (DUF881)
CPRO_RS03965	COG3856	small basic protein
CPRO_RS03970	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CPRO_RS03980	COG0573	inorganic phosphate transmembrane transporter activity
CPRO_RS03985	COG0581	inorganic phosphate transmembrane transporter activity
CPRO_RS03990	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CPRO_RS03995	COG0704	Plays a role in the regulation of phosphate uptake
CPRO_RS04010	COG5002	protein histidine kinase activity
CPRO_RS04025	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CPRO_RS04075	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CPRO_RS04080	COG0826	peptidase U32
CPRO_RS04090	COG0768	penicillin binding
CPRO_RS04115	COG3437	response regulator, receiver
CPRO_RS04120	COG0784	Response regulator, receiver
CPRO_RS04120	COG2205	protein histidine kinase activity
CPRO_RS04120	COG5002	protein histidine kinase activity
CPRO_RS04130	COG2832	Protein of unknown function (DUF454)
CPRO_RS04135	COG4988	ABC transporter
CPRO_RS04195	COG1705	Flagellar rod assembly protein muramidase FlgJ
CPRO_RS04195	COG1388	LysM domain
CPRO_RS04210	COG3628	GPW Gp25 family protein
CPRO_RS04215	COG3299	homolog of phage Mu protein gp47
CPRO_RS04255	COG2040	homocysteine
CPRO_RS04295	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
CPRO_RS04300	COG0298	carbon dioxide binding
CPRO_RS04305	COG0409	Hydrogenase expression formation protein
CPRO_RS04310	COG0309	Hydrogenase expression formation protein (HypE)
CPRO_RS04325	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
CPRO_RS04330	COG0473	3-isopropylmalate dehydrogenase activity
CPRO_RS04335	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CPRO_RS04340	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CPRO_RS04345	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CPRO_RS04350	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CPRO_RS04350	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CPRO_RS04355	COG0237	dephospho-CoA kinase activity
CPRO_RS04365	COG0747	negative chemotaxis
CPRO_RS04370	COG0537	adenosine 5'-monophosphoramidase activity
CPRO_RS04375	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CPRO_RS04435	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CPRO_RS04445	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CPRO_RS04455	COG0494	nUDIX hydrolase
CPRO_RS04470	COG2003	Belongs to the UPF0758 family
CPRO_RS04485	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CPRO_RS04505	COG0367	asparagine synthase
CPRO_RS04530	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CPRO_RS04535	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CPRO_RS04580	COG0473	3-isopropylmalate dehydrogenase activity
CPRO_RS04585	COG0066	3-isopropylmalate dehydratase activity
CPRO_RS04590	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CPRO_RS04595	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CPRO_RS04600	COG2188	Transcriptional regulator
CPRO_RS04605	COG0129	dihydroxy-acid dehydratase activity
CPRO_RS04610	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CPRO_RS04620	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CPRO_RS04620	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CPRO_RS04630	COG3409	Peptidoglycan-binding domain 1 protein
CPRO_RS04630	COG0860	N-Acetylmuramoyl-L-alanine amidase
CPRO_RS04635	COG2205	protein histidine kinase activity
CPRO_RS04635	COG0784	Response regulator, receiver
CPRO_RS04665	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CPRO_RS04680	COG3681	Belongs to the UPF0597 family
CPRO_RS04690	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CPRO_RS04695	COG0187	DNA topoisomerase II activity
CPRO_RS04710	COG0519	Catalyzes the synthesis of GMP from XMP
CPRO_RS04720	COG0800	Aldolase
CPRO_RS04730	COG1312	Catalyzes the dehydration of D-mannonate
CPRO_RS04735	COG0246	Mannitol dehydrogenase
CPRO_RS04740	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CPRO_RS04745	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CPRO_RS04750	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CPRO_RS04755	COG1063	alcohol dehydrogenase
CPRO_RS04760	COG1802	Transcriptional regulator
CPRO_RS04770	COG0277	FAD linked oxidase domain protein
CPRO_RS04780	COG2197	response regulator
CPRO_RS04810	COG1737	Transcriptional regulator
CPRO_RS04815	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CPRO_RS04825	COG1129	ABC transporter
CPRO_RS04830	COG1172	Belongs to the binding-protein-dependent transport system permease family
CPRO_RS04835	COG1940	carbohydrate kinase activity
CPRO_RS04840	COG0191	fructose-bisphosphate aldolase activity
CPRO_RS04845	COG0205	6-phosphofructokinase activity
CPRO_RS04855	COG1309	transcriptional regulator
CPRO_RS04860	COG1131	(ABC) transporter
CPRO_RS04905	COG0024	Methionine aminopeptidase
CPRO_RS04920	COG3706	GGDEF domain
CPRO_RS04925	COG0765	amino acid transport
CPRO_RS04930	COG0765	amino acid transport
CPRO_RS04935	COG1126	abc transporter atp-binding protein
CPRO_RS04950	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CPRO_RS04955	COG1854	S-ribosylhomocysteine lyase activity
CPRO_RS04960	COG0626	cystathionine gamma-synthase activity
CPRO_RS04965	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CPRO_RS04970	COG0583	DNA-binding transcription factor activity
CPRO_RS04985	COG2011	ABC-type metal ion transport system permease component
CPRO_RS05000	COG0674	pyruvate-flavodoxin oxidoreductase activity
CPRO_RS05005	COG1013	pyruvate-flavodoxin oxidoreductase activity
CPRO_RS05010	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CPRO_RS05020	COG1959	2 iron, 2 sulfur cluster binding
CPRO_RS05035	COG0482	sulfurtransferase activity
CPRO_RS05040	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CPRO_RS05045	COG1104	cysteine desulfurase activity
CPRO_RS05050	COG0037	tRNA processing
CPRO_RS05055	COG0460	homoserine dehydrogenase
CPRO_RS05065	COG1191	sigma factor activity
CPRO_RS05085	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CPRO_RS05090	COG0022	dehydrogenase e1 component
CPRO_RS05095	COG0508	dehydrogenase complex catalyzes the overall conversion of
CPRO_RS05115	COG4120	Belongs to the binding-protein-dependent transport system permease family
CPRO_RS05120	COG3842	ATPase activity
CPRO_RS05125	COG1959	2 iron, 2 sulfur cluster binding
CPRO_RS05130	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CPRO_RS05160	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CPRO_RS05165	COG0367	asparagine synthase
CPRO_RS05170	COG3069	C4-dicarboxylate transmembrane transporter activity
CPRO_RS05175	COG0583	DNA-binding transcription factor activity
CPRO_RS05180	COG1454	alcohol dehydrogenase
CPRO_RS05180	COG1012	belongs to the aldehyde dehydrogenase family
CPRO_RS05185	COG0513	Belongs to the DEAD box helicase family
CPRO_RS05190	COG1968	undecaprenyl-diphosphatase activity
CPRO_RS05195	COG1285	pathogenesis
CPRO_RS05225	COG0217	transcriptional regulatory protein
CPRO_RS05230	COG0582	viral genome integration into host DNA
CPRO_RS05305	COG0582	viral genome integration into host DNA
CPRO_RS05310	COG3728	DNA packaging
CPRO_RS05310	COG5484	DNA packaging
CPRO_RS05425	COG2268	Band 7 protein
CPRO_RS05455	COG2205	protein histidine kinase activity
CPRO_RS05460	COG0577	efflux transmembrane transporter activity
CPRO_RS05460	COG1136	(ABC) transporter
CPRO_RS05475	COG0275	rRNA processing
CPRO_RS05495	COG3973	AAA domain
CPRO_RS05500	COG2207	Transcriptional regulator
CPRO_RS05535	COG2226	methyltransferase
CPRO_RS05550	COG2207	Transcriptional regulator
CPRO_RS05550	COG3708	Transcriptional regulator
CPRO_RS05575	COG1132	(ABC) transporter
CPRO_RS05590	COG3279	Response regulator of the LytR AlgR family
CPRO_RS05600	COG1704	LemA family
CPRO_RS05615	COG0642	Histidine kinase
CPRO_RS05620	COG1136	(ABC) transporter
CPRO_RS05625	COG0577	efflux transmembrane transporter activity
CPRO_RS05640	COG1876	peptidase activity
CPRO_RS05660	COG0509	glycine decarboxylation via glycine cleavage system
CPRO_RS05670	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CPRO_RS05695	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CPRO_RS05705	COG0114	fumarate hydratase activity
CPRO_RS05710	COG1361	Conserved repeat domain
CPRO_RS05715	COG0281	malic enzyme
CPRO_RS05720	COG1671	Belongs to the UPF0178 family
CPRO_RS05730	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CPRO_RS05740	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
CPRO_RS05755	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CPRO_RS05765	COG1605	Chorismate mutase
CPRO_RS05765	COG0077	Prephenate dehydratase
CPRO_RS05770	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CPRO_RS05780	COG2001	Belongs to the MraZ family
CPRO_RS05785	COG0275	rRNA processing
CPRO_RS05795	COG0768	penicillin binding
CPRO_RS05800	COG0768	penicillin binding
CPRO_RS05810	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CPRO_RS05820	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CPRO_RS05825	COG0772	Belongs to the SEDS family
CPRO_RS05835	COG0525	valine-tRNA ligase activity
CPRO_RS05845	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CPRO_RS05850	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
CPRO_RS05855	COG4496	protein, YerC YecD
CPRO_RS05865	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CPRO_RS05870	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CPRO_RS05875	COG1116	anion transmembrane transporter activity
CPRO_RS05905	COG0840	transmembrane signaling receptor activity
CPRO_RS05910	COG0582	viral genome integration into host DNA
CPRO_RS05920	COG1114	Component of the transport system for branched-chain amino acids
CPRO_RS05930	COG1902	pentaerythritol trinitrate reductase activity
CPRO_RS05930	COG0446	pyridine nucleotide-disulphide oxidoreductase
CPRO_RS05935	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CPRO_RS05945	COG2210	Belongs to the sulfur carrier protein TusA family
CPRO_RS05955	COG2201	protein-glutamate methylesterase activity
CPRO_RS05965	COG1141	Ferredoxin
CPRO_RS05975	COG1151	hydroxylamine reductase activity
CPRO_RS06000	COG1115	amino acid carrier protein
CPRO_RS06030	COG3620	sequence-specific DNA binding
CPRO_RS06050	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CPRO_RS06055	COG1328	CTP reductase activity
CPRO_RS06055	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CPRO_RS06060	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CPRO_RS06065	COG1307	EDD domain protein, DegV family
CPRO_RS06070	COG1329	Transcriptional regulator
CPRO_RS06075	COG4956	integral membrane protein (PIN domain superfamily)
CPRO_RS06080	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CPRO_RS06085	COG0328	RNA-DNA hybrid ribonuclease activity
CPRO_RS06090	COG1278	Cold shock
CPRO_RS06100	COG0542	response to heat
CPRO_RS06105	COG2203	Gaf domain
CPRO_RS06105	COG2199	diguanylate cyclase activity
CPRO_RS06115	COG1739	Uncharacterized protein family UPF0029
CPRO_RS06120	COG2207	Transcriptional regulator
CPRO_RS06120	COG1917	Cupin 2, conserved barrel domain protein
CPRO_RS06125	COG0697	spore germination
CPRO_RS06140	COG2378	regulation of single-species biofilm formation
CPRO_RS06150	COG0456	acetyltransferase
CPRO_RS06165	COG2379	hydroxypyruvate reductase
CPRO_RS06170	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
CPRO_RS06175	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CPRO_RS06185	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CPRO_RS06195	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CPRO_RS06205	COG1686	Belongs to the peptidase S11 family
CPRO_RS06215	COG0551	DNA topoisomerase type I activity
CPRO_RS06215	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CPRO_RS06220	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
CPRO_RS06225	COG2244	polysaccharide biosynthetic process
CPRO_RS06230	COG0531	amino acid
CPRO_RS06235	COG1863	multisubunit Na H antiporter MnhE subunit
CPRO_RS06265	COG0651	ATP synthesis coupled electron transport
CPRO_RS06270	COG0651	ATP synthesis coupled electron transport
CPRO_RS06280	COG0651	ATP synthesis coupled electron transport
CPRO_RS06305	COG2199	diguanylate cyclase activity
CPRO_RS06310	COG0488	(ABC) transporter
CPRO_RS06345	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CPRO_RS06360	COG4474	Belongs to the UPF0398 family
CPRO_RS06465	COG3177	Filamentation induced by cAMP protein fic
CPRO_RS06495	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CPRO_RS06505	COG0582	viral genome integration into host DNA
CPRO_RS06525	COG0519	Catalyzes the synthesis of GMP from XMP
CPRO_RS06530	COG2252	PERMEase
CPRO_RS06535	COG0205	6-phosphofructokinase activity
CPRO_RS06545	COG0366	Alpha amylase catalytic
CPRO_RS06545	COG3103	Sh3 type 3 domain protein
CPRO_RS06550	COG0564	pseudouridine synthase activity
CPRO_RS06555	COG0542	response to heat
CPRO_RS06590	COG0095	Lipoate-protein ligase
CPRO_RS06645	COG2002	toxin-antitoxin pair type II binding
CPRO_RS06760	COG0739	heme binding
CPRO_RS06760	COG1196	nuclear chromosome segregation
CPRO_RS06760	COG0741	lytic transglycosylase activity
CPRO_RS06850	COG0326	Molecular chaperone. Has ATPase activity
CPRO_RS06895	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CPRO_RS06900	COG2135	peptidase activity
CPRO_RS06910	COG1522	sequence-specific DNA binding
CPRO_RS06910	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CPRO_RS06970	COG3118	belongs to the thioredoxin family
CPRO_RS06985	COG1151	hydroxylamine reductase activity
CPRO_RS06990	COG0583	DNA-binding transcription factor activity
CPRO_RS07005	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CPRO_RS07015	COG0840	transmembrane signaling receptor activity
CPRO_RS07040	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CPRO_RS07075	COG1131	(ABC) transporter
CPRO_RS07095	COG1012	belongs to the aldehyde dehydrogenase family
CPRO_RS07100	COG1757	Na H antiporter
CPRO_RS07105	COG1595	DNA-templated transcription, initiation
CPRO_RS07140	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CPRO_RS07165	COG1649	PFAM Uncharacterised BCR, COG1649
CPRO_RS07170	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CPRO_RS07185	COG1846	Transcriptional regulator
CPRO_RS07190	COG0840	transmembrane signaling receptor activity
CPRO_RS07210	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CPRO_RS07225	COG0038	chloride channel
CPRO_RS07230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CPRO_RS07235	COG0765	amino acid transport
CPRO_RS07240	COG1126	abc transporter atp-binding protein
CPRO_RS07245	COG0393	Putative heavy-metal-binding
CPRO_RS07260	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CPRO_RS07265	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CPRO_RS07270	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CPRO_RS07275	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CPRO_RS07320	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CPRO_RS07325	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CPRO_RS07335	COG0420	3'-5' exonuclease activity
CPRO_RS07340	COG0419	ATPase involved in DNA repair
CPRO_RS07345	COG0419	ATPase involved in DNA repair
CPRO_RS07355	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CPRO_RS07360	COG2873	o-acetylhomoserine
CPRO_RS07365	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
CPRO_RS07370	COG2385	sporulation resulting in formation of a cellular spore
CPRO_RS07380	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CPRO_RS07385	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CPRO_RS07395	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CPRO_RS07400	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CPRO_RS07400	COG0072	phenylalanine-tRNA ligase activity
CPRO_RS07415	COG1217	gtp-binding protein TYPA
CPRO_RS07420	COG2244	polysaccharide biosynthetic process
CPRO_RS07430	COG0322	excinuclease ABC activity
CPRO_RS07435	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CPRO_RS07440	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CPRO_RS07445	COG1660	Displays ATPase and GTPase activities
CPRO_RS07450	COG1481	regulation of sporulation
CPRO_RS07455	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CPRO_RS07460	COG0116	Belongs to the methyltransferase superfamily
CPRO_RS07470	COG1862	Preprotein translocase
CPRO_RS07480	COG3845	ABC transporter
CPRO_RS07490	COG1079	Belongs to the binding-protein-dependent transport system permease family
CPRO_RS07500	COG1957	nucleoside hydrolase
CPRO_RS07510	COG1773	rubredoxin
CPRO_RS07510	COG1592	Rubrerythrin
CPRO_RS07525	COG4942	peptidase
CPRO_RS07535	COG0495	leucyl-tRNA aminoacylation
CPRO_RS07540	COG1132	(ABC) transporter
CPRO_RS07545	COG1132	(ABC) transporter
CPRO_RS07550	COG1846	Transcriptional regulator
CPRO_RS07565	COG2176	DNA-directed DNA polymerase activity
CPRO_RS07570	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CPRO_RS07580	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CPRO_RS07585	COG4589	Belongs to the CDS family
CPRO_RS07590	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CPRO_RS07595	COG0233	cytoplasmic translational termination
CPRO_RS07600	COG0528	UMP kinase activity
CPRO_RS07605	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CPRO_RS07610	COG0052	Belongs to the universal ribosomal protein uS2 family
CPRO_RS07615	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CPRO_RS07620	COG0758	DNA mediated transformation
CPRO_RS07620	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CPRO_RS07625	COG0606	chelatase, subunit chli
CPRO_RS07635	COG0840	transmembrane signaling receptor activity
CPRO_RS07650	COG1404	Belongs to the peptidase S8 family
CPRO_RS07665	COG2200	EAL domain
CPRO_RS07665	COG2199	diguanylate cyclase activity
CPRO_RS07675	COG0688	phosphatidylethanolamine metabolic process
CPRO_RS07680	COG1183	phosphatidylcholine synthase activity
CPRO_RS07700	COG1114	Component of the transport system for branched-chain amino acids
CPRO_RS07705	COG0436	Aminotransferase
CPRO_RS07710	COG0427	acetyl-CoA hydrolase
CPRO_RS07720	COG1144	Oxidoreductase
CPRO_RS07725	COG1802	Transcriptional regulator
CPRO_RS07740	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CPRO_RS07745	COG0352	thiamine-phosphate diphosphorylase activity
CPRO_RS07755	COG2022	thiamine diphosphate biosynthetic process
CPRO_RS07760	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CPRO_RS07775	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CPRO_RS07780	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CPRO_RS07790	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CPRO_RS07795	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CPRO_RS07805	COG1309	transcriptional regulator
CPRO_RS07810	COG0450	alkyl hydroperoxide reductase
CPRO_RS07845	COG1151	hydroxylamine reductase activity
CPRO_RS07850	COG2610	gluconate transmembrane transporter activity
CPRO_RS07855	COG1024	Enoyl-CoA hydratase
CPRO_RS07860	COG4670	ketone body catabolic process
CPRO_RS07870	COG1013	pyruvate-flavodoxin oxidoreductase activity
CPRO_RS07870	COG0674	pyruvate-flavodoxin oxidoreductase activity
CPRO_RS07870	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CPRO_RS07870	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
CPRO_RS07880	COG0723	plastoquinol--plastocyanin reductase activity
CPRO_RS07880	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CPRO_RS07885	COG3546	catalase activity
CPRO_RS07905	COG1607	acyl-coa hydrolase
CPRO_RS07910	COG1012	belongs to the aldehyde dehydrogenase family
CPRO_RS07920	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CPRO_RS07945	COG0733	neurotransmitter:sodium symporter activity
CPRO_RS07960	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CPRO_RS07980	COG1733	regulation of RNA biosynthetic process
CPRO_RS07990	COG2205	protein histidine kinase activity
CPRO_RS07995	COG0745	RESPONSE REGULATOR receiver
CPRO_RS08005	COG0569	domain protein
CPRO_RS08015	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CPRO_RS08020	COG2080	2 iron, 2 sulfur cluster binding
CPRO_RS08030	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CPRO_RS08050	COG0412	Dienelactone hydrolase
CPRO_RS08100	COG0277	FAD linked oxidase domain protein
CPRO_RS08130	COG0701	Predicted permease
CPRO_RS08140	COG0798	PFAM Bile acid sodium symporter
CPRO_RS08150	COG0390	transport system, permease component
CPRO_RS08165	COG2207	Transcriptional regulator
CPRO_RS08165	COG3708	Transcriptional regulator
CPRO_RS08180	COG5002	protein histidine kinase activity
CPRO_RS08185	COG0745	RESPONSE REGULATOR receiver
CPRO_RS08200	COG0105	UTP biosynthetic process
CPRO_RS08205	COG1309	transcriptional regulator
CPRO_RS08220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CPRO_RS08225	COG3191	aminopeptidase activity
CPRO_RS08240	COG4145	pantothenate transmembrane transporter activity
CPRO_RS08250	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CPRO_RS08255	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CPRO_RS08260	COG1414	Transcriptional regulator
CPRO_RS08265	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CPRO_RS08280	COG0840	transmembrane signaling receptor activity
CPRO_RS08330	COG0745	RESPONSE REGULATOR receiver
CPRO_RS08350	COG2208	phosphoserine phosphatase activity
CPRO_RS08350	COG2770	Histidine kinase
CPRO_RS08365	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CPRO_RS08365	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CPRO_RS08370	COG1366	Belongs to the anti-sigma-factor antagonist family
CPRO_RS08375	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CPRO_RS08390	COG2274	protein secretion by the type I secretion system
CPRO_RS08410	COG2199	diguanylate cyclase activity
CPRO_RS08440	COG1309	transcriptional regulator
CPRO_RS08450	COG2223	nitrite transmembrane transporter activity
CPRO_RS08455	COG5609	conserved protein (DUF2294)
CPRO_RS08475	COG0521	Mo-molybdopterin cofactor biosynthetic process
CPRO_RS08490	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CPRO_RS08495	COG0303	'Molybdopterin
CPRO_RS08500	COG0303	'Molybdopterin
CPRO_RS08620	COG0210	DNA helicase
CPRO_RS08625	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CPRO_RS08655	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CPRO_RS08680	COG1924	4 iron, 4 sulfur cluster binding
CPRO_RS08715	COG1151	hydroxylamine reductase activity
CPRO_RS08720	COG1773	rubredoxin
CPRO_RS08740	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CPRO_RS08775	COG1151	hydroxylamine reductase activity
CPRO_RS08785	COG1141	Ferredoxin
CPRO_RS08815	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CPRO_RS08820	COG2195	Cleaves the N-terminal amino acid of tripeptides
CPRO_RS08825	COG1288	antiporter activity
CPRO_RS08830	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CPRO_RS08845	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CPRO_RS08845	COG2199	diguanylate cyclase activity
CPRO_RS08855	COG0450	alkyl hydroperoxide reductase
CPRO_RS08870	COG0697	spore germination
CPRO_RS08885	COG1574	metal-dependent hydrolase with the TIM-barrel fold
CPRO_RS08930	COG3012	SEC-C Motif Domain Protein
CPRO_RS08940	COG0210	DNA helicase
CPRO_RS08945	COG1196	nuclear chromosome segregation
CPRO_RS09025	COG2826	transposase and inactivated derivatives, IS30 family
CPRO_RS09040	COG4443	Transcriptional Coactivator p15 (PC4)
CPRO_RS09085	COG1525	nuclease
CPRO_RS09095	COG3843	relaxase mobilization nuclease domain protein
CPRO_RS09140	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
CPRO_RS09170	COG0791	NLP P60 protein
CPRO_RS09170	COG0741	lytic transglycosylase activity
CPRO_RS09245	COG1192	Involved in chromosome partitioning
CPRO_RS09255	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CPRO_RS09300	COG1309	transcriptional regulator
CPRO_RS09320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CPRO_RS09355	COG0791	NLP P60 protein
CPRO_RS09360	COG2226	methyltransferase
CPRO_RS09380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CPRO_RS09390	COG0789	Transcriptional regulator
CPRO_RS09455	COG2378	regulation of single-species biofilm formation
CPRO_RS09460	COG2378	regulation of single-species biofilm formation
CPRO_RS09475	COG0789	Transcriptional regulator
CPRO_RS09480	COG1131	(ABC) transporter
CPRO_RS09525	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CPRO_RS09530	COG3344	reverse transcriptase
CPRO_RS09570	COG2088	sporulation resulting in formation of a cellular spore
CPRO_RS09600	COG4974	Belongs to the 'phage' integrase family
CPRO_RS09605	COG4974	Belongs to the 'phage' integrase family
CPRO_RS09610	COG4974	Belongs to the 'phage' integrase family
CPRO_RS09780	COG3481	metal-dependent phosphohydrolase, HD sub domain
CPRO_RS09810	COG0004	ammonium transporteR
CPRO_RS09815	COG1191	sigma factor activity
CPRO_RS09825	COG1802	Transcriptional regulator
CPRO_RS09835	COG0482	sulfurtransferase activity
CPRO_RS09840	COG1283	sodium-dependent phosphate transmembrane transporter activity
CPRO_RS09845	COG0527	aspartate kinase activity
CPRO_RS09845	COG0460	homoserine dehydrogenase
CPRO_RS09860	COG0010	Belongs to the arginase family
CPRO_RS09865	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CPRO_RS09870	COG1982	Orn Lys Arg decarboxylase major
CPRO_RS09880	COG0583	DNA-binding transcription factor activity
CPRO_RS09885	COG1063	alcohol dehydrogenase
CPRO_RS09890	COG5002	protein histidine kinase activity
CPRO_RS09895	COG0745	RESPONSE REGULATOR receiver
CPRO_RS09905	COG0038	chloride channel
CPRO_RS09910	COG2964	Protein conserved in bacteria
CPRO_RS09915	COG1584	GPR1 FUN34 yaaH family protein
CPRO_RS09920	COG0336	Belongs to the RNA methyltransferase TrmD family
CPRO_RS09925	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CPRO_RS09930	COG1837	Belongs to the UPF0109 family
CPRO_RS09935	COG0228	four-way junction DNA binding
CPRO_RS09940	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CPRO_RS09950	COG0406	alpha-ribazole phosphatase activity
CPRO_RS09960	COG1854	S-ribosylhomocysteine lyase activity
CPRO_RS09965	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CPRO_RS09970	COG1760	l-serine dehydratase
CPRO_RS09975	COG1760	l-serine dehydratase
CPRO_RS09980	COG0459	protein refolding
CPRO_RS09985	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CPRO_RS09995	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CPRO_RS10000	COG0822	iron-sulfur transferase activity
CPRO_RS10010	COG1396	sequence-specific DNA binding
CPRO_RS10015	COG0497	DNA recombination
CPRO_RS10020	COG1438	arginine binding
CPRO_RS10030	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
CPRO_RS10035	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CPRO_RS10040	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
CPRO_RS10050	COG1722	exodeoxyribonuclease VII activity
CPRO_RS10055	COG1570	exodeoxyribonuclease VII activity
CPRO_RS10065	COG1302	Protein conserved in bacteria
CPRO_RS10105	COG3854	ATPases associated with a variety of cellular activities
CPRO_RS10110	COG3279	Response regulator of the LytR AlgR family
CPRO_RS10140	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CPRO_RS10160	COG0658	competence protein
CPRO_RS10160	COG2333	competence protein COMEC
CPRO_RS10170	COG5002	protein histidine kinase activity
CPRO_RS10175	COG0745	RESPONSE REGULATOR receiver
CPRO_RS10185	COG1686	Belongs to the peptidase S11 family
CPRO_RS10190	COG0791	NLP P60 protein
CPRO_RS10190	COG1388	LysM domain
CPRO_RS10195	COG1132	(ABC) transporter
CPRO_RS10215	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CPRO_RS10230	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
CPRO_RS10240	COG3706	GGDEF domain
CPRO_RS10340	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CPRO_RS10430	COG1191	sigma factor activity
CPRO_RS10435	COG2172	sigma factor antagonist activity
CPRO_RS10440	COG1366	Belongs to the anti-sigma-factor antagonist family
CPRO_RS10475	COG0493	'glutamate synthase
CPRO_RS10485	COG1953	Uracil, thiamine, allantoin
CPRO_RS10500	COG4978	Transcriptional regulator
CPRO_RS10500	COG0789	Transcriptional regulator
CPRO_RS10515	COG1607	acyl-coa hydrolase
CPRO_RS10520	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CPRO_RS10555	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CPRO_RS10565	COG1459	type II secretion system
CPRO_RS10575	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CPRO_RS10605	COG1846	Transcriptional regulator
CPRO_RS10610	COG0826	peptidase U32
CPRO_RS10615	COG4122	O-methyltransferase activity
CPRO_RS10620	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CPRO_RS10655	COG1194	a g-specific adenine glycosylase
CPRO_RS10660	COG2116	formate transmembrane transporter activity
CPRO_RS10665	COG3048	D-serine ammonia-lyase activity
CPRO_RS10675	COG2205	protein histidine kinase activity
CPRO_RS10680	COG0745	RESPONSE REGULATOR receiver
CPRO_RS10715	COG1196	nuclear chromosome segregation
CPRO_RS10720	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CPRO_RS10725	COG0540	Belongs to the ATCase OTCase family
CPRO_RS10730	COG0564	pseudouridine synthase activity
CPRO_RS10735	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CPRO_RS10755	COG1799	cell septum assembly
CPRO_RS10760	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CPRO_RS10775	COG0508	dehydrogenase complex catalyzes the overall conversion of
CPRO_RS10780	COG3199	ATP-NAD kinase
CPRO_RS10785	COG0022	dehydrogenase e1 component
CPRO_RS10790	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CPRO_RS10805	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CPRO_RS10835	COG1733	regulation of RNA biosynthetic process
CPRO_RS10850	COG1396	sequence-specific DNA binding
CPRO_RS10855	COG1882	Formate acetyltransferase
CPRO_RS10860	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CPRO_RS10885	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CPRO_RS10890	COG1115	amino acid carrier protein
CPRO_RS10915	COG3688	RNA-binding protein containing a PIN domain
CPRO_RS10920	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CPRO_RS10930	COG0215	cysteine-tRNA ligase activity
CPRO_RS10935	COG1045	serine acetyltransferase
CPRO_RS10940	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CPRO_RS11020	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CPRO_RS11025	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CPRO_RS11025	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CPRO_RS11030	COG5002	protein histidine kinase activity
CPRO_RS11040	COG0745	RESPONSE REGULATOR receiver
CPRO_RS11045	COG1193	negative regulation of DNA recombination
CPRO_RS11050	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
CPRO_RS11065	COG1011	Hydrolase
CPRO_RS11080	COG1234	tRNA 3'-trailer cleavage
CPRO_RS11085	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CPRO_RS11095	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CPRO_RS11100	COG1162	GTPase activity
CPRO_RS11105	COG0515	serine threonine protein kinase
CPRO_RS11105	COG2815	serine threonine protein kinase
CPRO_RS11105	COG2815	serine threonine protein kinase
CPRO_RS11105	COG0515	serine threonine protein kinase
CPRO_RS11115	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CPRO_RS11120	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CPRO_RS11120	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CPRO_RS11125	COG2738	Putative neutral zinc metallopeptidase
CPRO_RS11130	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CPRO_RS11135	COG0242	peptide deformylase activity
CPRO_RS11140	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CPRO_RS11145	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CPRO_RS11155	COG0194	GDP metabolic process
CPRO_RS11165	COG1561	YicC-like family, N-terminal region
CPRO_RS11195	COG0739	heme binding
CPRO_RS11205	COG1162	GTPase activity
CPRO_RS11210	COG1683	Conserved Protein
CPRO_RS11220	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CPRO_RS11225	COG1132	(ABC) transporter
CPRO_RS11235	COG0346	lactoylglutathione lyase activity
CPRO_RS11360	COG2084	Dehydrogenase
CPRO_RS11370	COG0508	dehydrogenase complex catalyzes the overall conversion of
CPRO_RS11375	COG0022	dehydrogenase e1 component
CPRO_RS11380	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CPRO_RS11395	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CPRO_RS11405	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CPRO_RS11410	COG0151	Belongs to the GarS family
CPRO_RS11415	COG0138	bifunctional purine biosynthesis protein purh
CPRO_RS11420	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CPRO_RS11430	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CPRO_RS11435	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CPRO_RS11440	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CPRO_RS11445	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CPRO_RS11450	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CPRO_RS11455	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CPRO_RS11465	COG0543	2 iron, 2 sulfur cluster binding
CPRO_RS11470	COG0167	dihydroorotate dehydrogenase activity
CPRO_RS11475	COG0284	orotidine-5'-phosphate decarboxylase activity
CPRO_RS11485	COG0540	Belongs to the ATCase OTCase family
CPRO_RS11515	COG0628	permease
CPRO_RS11520	COG2195	Cleaves the N-terminal amino acid of tripeptides
CPRO_RS11525	COG0571	ribonuclease III activity
CPRO_RS11530	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CPRO_RS11550	COG0280	phosphate acetyltransferase
CPRO_RS11565	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CPRO_RS11570	COG0416	fatty acid biosynthetic process
CPRO_RS11575	COG1323	Belongs to the UPF0348 family
CPRO_RS11580	COG3314	Sporulation integral membrane protein YlbJ
CPRO_RS11590	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CPRO_RS11595	COG0742	ribosomal rna small subunit methyltransferase
CPRO_RS11620	COG1136	(ABC) transporter
CPRO_RS11620	COG0577	efflux transmembrane transporter activity
CPRO_RS11625	COG1136	(ABC) transporter
CPRO_RS11630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CPRO_RS11645	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CPRO_RS11830	COG0037	tRNA processing
CPRO_RS11860	COG2002	toxin-antitoxin pair type II binding
CPRO_RS11900	COG2856	Zn peptidase
CPRO_RS11950	COG0535	radical SAM domain protein
CPRO_RS11960	COG1278	Cold shock
CPRO_RS11975	COG1461	Dihydroxyacetone kinase
CPRO_RS11980	COG1302	Protein conserved in bacteria
CPRO_RS11995	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CPRO_RS12000	COG1028	Short-chain dehydrogenase reductase Sdr
CPRO_RS12090	COG2195	Cleaves the N-terminal amino acid of tripeptides
CPRO_RS12095	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CPRO_RS12100	COG0693	protein deglycase activity
CPRO_RS12105	COG4974	Belongs to the 'phage' integrase family
CPRO_RS12110	COG1300	Membrane
CPRO_RS12135	COG0750	zinc metalloprotease
CPRO_RS12150	COG0148	phosphopyruvate hydratase activity
CPRO_RS12155	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CPRO_RS12160	COG0149	triose-phosphate isomerase activity
CPRO_RS12170	COG0126	phosphoglycerate kinase activity
CPRO_RS12190	COG2339	peptidase activity
CPRO_RS12195	COG0577	efflux transmembrane transporter activity
CPRO_RS12205	COG1136	(ABC) transporter
CPRO_RS12215	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CPRO_RS12220	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CPRO_RS12225	COG2155	Conserved Protein
CPRO_RS12230	COG0612	Peptidase, M16
CPRO_RS12235	COG1185	polyribonucleotide nucleotidyltransferase activity
CPRO_RS12250	COG0196	riboflavin kinase activity
CPRO_RS12255	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CPRO_RS12270	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CPRO_RS12280	COG2740	Nucleic-acid-binding protein implicated in transcription termination
CPRO_RS12285	COG0195	Participates in both transcription termination and antitermination
CPRO_RS12290	COG0779	Required for maturation of 30S ribosomal subunits
CPRO_RS12295	COG1811	Na channel or pump
CPRO_RS12300	COG1126	abc transporter atp-binding protein
CPRO_RS12305	COG0765	amino acid transport
CPRO_RS12315	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CPRO_RS12325	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CPRO_RS12325	COG0539	negative regulation of cytoplasmic translation
CPRO_RS12330	COG0204	Acyl-transferase
CPRO_RS12335	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CPRO_RS12340	COG2081	HI0933 family
CPRO_RS12345	COG0406	alpha-ribazole phosphatase activity
CPRO_RS12350	COG1187	pseudouridine synthase activity
CPRO_RS12355	COG1686	Belongs to the peptidase S11 family
CPRO_RS12365	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CPRO_RS12370	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CPRO_RS12400	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CPRO_RS12420	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CPRO_RS12425	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CPRO_RS12445	COG1966	Carbon starvation protein
CPRO_RS12450	COG0708	Exodeoxyribonuclease III
CPRO_RS12465	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CPRO_RS12470	COG0159	tryptophan synthase activity
CPRO_RS12480	COG0135	phosphoribosylanthranilate isomerase activity
CPRO_RS12485	COG0134	indole-3-glycerol-phosphate synthase activity
CPRO_RS12490	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CPRO_RS12495	COG0512	Glutamine amidotransferase of anthranilate synthase
CPRO_RS12510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CPRO_RS12520	COG0484	heat shock protein binding
CPRO_RS12525	COG0443	Heat shock 70 kDa protein
CPRO_RS12530	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CPRO_RS12540	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CPRO_RS12545	COG1368	sulfuric ester hydrolase activity
CPRO_RS12560	COG1476	TRANSCRIPTIONal
CPRO_RS12585	COG0006	proline dipeptidase activity
CPRO_RS12590	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CPRO_RS12605	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CPRO_RS12615	COG1067	ATP-dependent peptidase activity
CPRO_RS12615	COG0470	DNA polymerase III
CPRO_RS12620	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CPRO_RS12625	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CPRO_RS12630	COG0049	tRNA binding
CPRO_RS12635	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CPRO_RS12640	COG1136	(ABC) transporter
CPRO_RS12640	COG0577	efflux transmembrane transporter activity
CPRO_RS12655	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CPRO_RS12660	COG0085	RNA polymerase activity
CPRO_RS12665	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CPRO_RS12675	COG0222	ribosome binding
CPRO_RS12685	COG0081	regulation of translation
CPRO_RS12695	COG0250	Participates in transcription elongation, termination and antitermination
CPRO_RS12705	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CPRO_RS12720	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CPRO_RS12730	COG0793	Belongs to the peptidase S41A family
CPRO_RS12735	COG2177	Part of the ABC transporter FtsEX involved in
CPRO_RS12740	COG2884	Cell division ATP-binding protein ftsE
CPRO_RS12745	COG2508	Transcriptional regulator
CPRO_RS12750	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
CPRO_RS12775	COG0438	transferase activity, transferring glycosyl groups
CPRO_RS12780	COG0728	peptidoglycan biosynthetic process
CPRO_RS12795	COG2337	Toxic component of a toxin-antitoxin (TA) module
CPRO_RS12810	COG1316	TRANSCRIPTIONal
CPRO_RS12815	COG1316	TRANSCRIPTIONal
CPRO_RS12825	COG0733	neurotransmitter:sodium symporter activity
CPRO_RS12830	COG2239	Acts as a magnesium transporter
CPRO_RS12835	COG0305	Participates in initiation and elongation during chromosome replication
CPRO_RS12840	COG0359	binds to the 23S rRNA
CPRO_RS12845	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
CPRO_RS12860	COG0714	Associated with various cellular activities
CPRO_RS12865	COG0628	permease
CPRO_RS12880	COG2002	toxin-antitoxin pair type II binding
CPRO_RS12885	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CPRO_RS12890	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CPRO_RS12905	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CPRO_RS12915	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CPRO_RS12930	COG4472	Bacterial protein of unknown function (DUF965)
CPRO_RS12935	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CPRO_RS12940	COG0561	phosphatase activity
CPRO_RS12955	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CPRO_RS12960	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CPRO_RS12965	COG0668	transmembrane transport
CPRO_RS12985	COG2217	Heavy metal translocating P-type atpase
CPRO_RS12995	COG0583	DNA-binding transcription factor activity
CPRO_RS13010	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CPRO_RS13015	COG0193	aminoacyl-tRNA hydrolase activity
CPRO_RS13020	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CPRO_RS13030	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CPRO_RS13040	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CPRO_RS13045	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CPRO_RS13050	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CPRO_RS13055	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CPRO_RS13060	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CPRO_RS13085	COG5002	protein histidine kinase activity
CPRO_RS13090	COG0745	RESPONSE REGULATOR receiver
CPRO_RS13095	COG2205	protein histidine kinase activity
CPRO_RS13095	COG0784	Response regulator, receiver
CPRO_RS13110	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CPRO_RS13115	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
CPRO_RS13120	COG1774	PSP1 C-terminal conserved region
CPRO_RS13125	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CPRO_RS13130	COG3870	Protein conserved in bacteria
CPRO_RS13135	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CPRO_RS13145	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CPRO_RS13155	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CPRO_RS13165	COG0698	ribose 5-phosphate isomerase
CPRO_RS13170	COG0009	L-threonylcarbamoyladenylate synthase
CPRO_RS13175	COG0653	protein targeting
CPRO_RS13190	COG0504	CTP synthase activity
CPRO_RS13205	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CPRO_RS13215	COG0537	adenosine 5'-monophosphoramidase activity
CPRO_RS13230	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CPRO_RS13240	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
CPRO_RS13245	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CPRO_RS13255	COG1040	competence protein
CPRO_RS13260	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CPRO_RS13265	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CPRO_RS13310	COG0726	polysaccharide deacetylase
CPRO_RS13325	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CPRO_RS13335	COG2233	PERMEase
CPRO_RS13345	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CPRO_RS13350	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CPRO_RS13355	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CPRO_RS13370	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CPRO_RS13370	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CPRO_RS13390	COG0037	tRNA processing
CPRO_RS13410	COG0426	domain, Protein
CPRO_RS13410	COG1773	rubredoxin
CPRO_RS13415	COG0166	Belongs to the GPI family
CPRO_RS13425	COG1802	Transcriptional regulator
CPRO_RS13430	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CPRO_RS13445	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CPRO_RS13445	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CPRO_RS13450	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CPRO_RS13455	COG0628	permease
CPRO_RS13470	COG0024	Methionine aminopeptidase
CPRO_RS13665	COG4974	Belongs to the 'phage' integrase family
CPRO_RS13675	COG2431	L-lysine efflux transmembrane transporter activity
CPRO_RS13685	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
CPRO_RS13690	COG0488	(ABC) transporter
CPRO_RS13700	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CPRO_RS13710	COG0371	Dehydrogenase
CPRO_RS13715	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
CPRO_RS13720	COG2086	electron transfer activity
CPRO_RS13725	COG1960	acyl-CoA dehydrogenase activity
CPRO_RS13730	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
CPRO_RS13730	COG3933	PFAM sigma-54 factor interaction domain-containing protein
CPRO_RS13735	COG0658	competence protein
CPRO_RS13735	COG2333	competence protein COMEC
CPRO_RS13740	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CPRO_RS13750	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CPRO_RS13760	COG1970	mechanosensitive ion channel activity
CPRO_RS13765	COG2884	Cell division ATP-binding protein ftsE
CPRO_RS13785	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CPRO_RS13790	COG1192	Involved in chromosome partitioning
CPRO_RS13800	COG0835	chemotaxis
CPRO_RS13800	COG0784	Response regulator, receiver
CPRO_RS13805	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CPRO_RS13810	COG1776	CheC inhibitor of MCP methylation
CPRO_RS13815	COG4786	Flagellar basal body rod
CPRO_RS13820	COG4786	Flagellar basal body rod
CPRO_RS13825	COG1191	sigma factor activity
CPRO_RS13830	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CPRO_RS13835	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CPRO_RS13840	COG1684	flagellar biosynthetic protein fliR
CPRO_RS13845	COG1987	bacterial-type flagellum assembly
CPRO_RS13860	COG2201	protein-glutamate methylesterase activity
CPRO_RS13865	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CPRO_RS13865	COG1776	CheC inhibitor of MCP methylation
CPRO_RS13890	COG4786	Flagellar basal body rod
CPRO_RS13910	COG1361	Conserved repeat domain
CPRO_RS13920	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CPRO_RS13945	COG2201	protein-glutamate methylesterase activity
CPRO_RS13950	COG2747	anti-sigma28 factor FlgM
CPRO_RS13975	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
CPRO_RS13980	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CPRO_RS13990	COG1126	abc transporter atp-binding protein
CPRO_RS13995	COG0765	amino acid transport
CPRO_RS14065	COG0058	SHG alpha-glucan phosphorylase activity
CPRO_RS14085	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CPRO_RS14090	COG2890	protein-(glutamine-N5) methyltransferase activity
CPRO_RS14095	COG3872	metal-dependent enzyme
CPRO_RS14100	COG0254	rRNA binding
CPRO_RS14105	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CPRO_RS14140	COG0671	phosphoesterase, PA-phosphatase related
CPRO_RS14180	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CPRO_RS14185	COG0776	regulation of translation
CPRO_RS14190	COG3956	TIGRFAM MazG family protein
CPRO_RS14200	COG0493	'glutamate synthase
CPRO_RS14200	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CPRO_RS14205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CPRO_RS14210	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CPRO_RS14220	COG0602	queuosine metabolic process
CPRO_RS14225	COG0756	dUTP diphosphatase activity
CPRO_RS14230	COG2720	vancomycin resistance protein
CPRO_RS14240	COG2011	ABC-type metal ion transport system permease component
CPRO_RS14245	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CPRO_RS14255	COG0352	thiamine-phosphate diphosphorylase activity
CPRO_RS14255	COG0351	phosphomethylpyrimidine kinase
CPRO_RS14280	COG0860	N-Acetylmuramoyl-L-alanine amidase
CPRO_RS14290	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CPRO_RS14305	COG0179	Fumarylacetoacetate (FAA) hydrolase
CPRO_RS14310	COG0137	argininosuccinate synthase activity
CPRO_RS14315	COG0165	Argininosuccinate lyase
CPRO_RS14345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CPRO_RS14350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CPRO_RS14355	COG1396	sequence-specific DNA binding
CPRO_RS14360	COG3842	ATPase activity
CPRO_RS14365	COG1176	ABC-type spermidine putrescine transport system, permease component I
CPRO_RS14395	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CPRO_RS14410	COG1982	Orn Lys Arg decarboxylase major
CPRO_RS14430	COG0517	IMP dehydrogenase activity
CPRO_RS14430	COG1125	glycine betaine transport
CPRO_RS14435	COG1174	glycine betaine transport
CPRO_RS14440	COG1174	glycine betaine transport
CPRO_RS14465	COG0583	DNA-binding transcription factor activity
CPRO_RS14490	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CPRO_RS14500	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CPRO_RS14505	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CPRO_RS14535	COG0662	Cupin 2, conserved barrel domain protein
CPRO_RS14540	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CPRO_RS14545	COG1393	Belongs to the ArsC family
CPRO_RS14560	COG1573	uracil-dna glycosylase
CPRO_RS14565	COG0457	Tetratricopeptide repeat
CPRO_RS14565	COG0705	Rhomboid family
CPRO_RS14585	COG2171	N-acyltransferase activity
CPRO_RS14655	COG0745	RESPONSE REGULATOR receiver
CPRO_RS14715	COG0357	Ribosomal RNA small subunit methyltransferase G
CPRO_RS14725	COG0445	tRNA wobble uridine modification
CPRO_RS14730	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CPRO_RS14735	COG1847	R3H domain protein
CPRO_RS14745	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CPRO_RS14750	COG0594	ribonuclease P activity
CPRO_RS14755	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CPRO_RS14760	COG3437	response regulator, receiver
CPRO_RS14785	COG3546	catalase activity
CPRO_RS14800	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CPRO_RS14870	COG0582	viral genome integration into host DNA
CPRO_RS15030	COG0552	protein localization to endoplasmic reticulum
CPRO_RS15105	COG0381	UDP-N-acetylglucosamine 2-epimerase activity