locus-tag	class	description
ETAA8_RS00010	COG0592	DNA-directed DNA polymerase activity
ETAA8_RS00050	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ETAA8_RS00245	COG2186	Transcriptional regulator
ETAA8_RS00250	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ETAA8_RS00255	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ETAA8_RS00265	COG0179	Fumarylacetoacetate (FAA) hydrolase
ETAA8_RS00280	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_RS00285	COG0022	dehydrogenase e1 component
ETAA8_RS00310	COG2186	Transcriptional regulator
ETAA8_RS00350	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ETAA8_RS00355	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_RS00390	COG1525	nuclease
ETAA8_RS00445	COG0673	inositol 2-dehydrogenase activity
ETAA8_RS00455	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ETAA8_RS00470	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ETAA8_RS00480	COG2186	Transcriptional regulator
ETAA8_RS00525	COG0673	inositol 2-dehydrogenase activity
ETAA8_RS00555	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ETAA8_RS00665	COG0673	inositol 2-dehydrogenase activity
ETAA8_RS00685	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ETAA8_RS00695	COG0363	glucosamine-6-phosphate deaminase activity
ETAA8_RS00735	COG0515	serine threonine protein kinase
ETAA8_RS00735	COG2815	serine threonine protein kinase
ETAA8_RS00755	COG2815	serine threonine protein kinase
ETAA8_RS00755	COG0515	serine threonine protein kinase
ETAA8_RS00800	COG3119	arylsulfatase activity
ETAA8_RS00850	COG1940	carbohydrate kinase activity
ETAA8_RS00850	COG1846	Transcriptional regulator
ETAA8_RS00865	COG0129	dihydroxy-acid dehydratase activity
ETAA8_RS00960	COG0542	response to heat
ETAA8_RS00980	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
ETAA8_RS01005	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ETAA8_RS01025	COG1966	Carbon starvation protein
ETAA8_RS01050	COG0673	inositol 2-dehydrogenase activity
ETAA8_RS01065	COG1595	DNA-templated transcription, initiation
ETAA8_RS01075	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ETAA8_RS01090	COG0531	amino acid
ETAA8_RS01125	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ETAA8_RS01145	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ETAA8_RS01165	COG2755	lipolytic protein G-D-S-L family
ETAA8_RS01165	COG0657	acetylesterase activity
ETAA8_RS01190	COG2195	Cleaves the N-terminal amino acid of tripeptides
ETAA8_RS01200	COG0438	transferase activity, transferring glycosyl groups
ETAA8_RS01225	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ETAA8_RS01230	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ETAA8_RS01235	COG3842	ATPase activity
ETAA8_RS01240	COG0195	Participates in both transcription termination and antitermination
ETAA8_RS01245	COG0616	signal peptide processing
ETAA8_RS01275	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ETAA8_RS01280	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ETAA8_RS01305	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_RS01390	COG2201	protein-glutamate methylesterase activity
ETAA8_RS01430	COG1285	pathogenesis
ETAA8_RS01440	COG2226	methyltransferase
ETAA8_RS01470	COG1381	Involved in DNA repair and RecF pathway recombination
ETAA8_RS01505	COG4191	Histidine kinase
ETAA8_RS01510	COG1872	DUF167
ETAA8_RS01515	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_RS01520	COG0318	PFAM AMP-dependent synthetase and ligase
ETAA8_RS01535	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ETAA8_RS01545	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ETAA8_RS01550	COG0493	'glutamate synthase
ETAA8_RS01610	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ETAA8_RS01615	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ETAA8_RS01620	COG2133	pyrroloquinoline quinone binding
ETAA8_RS01645	COG3002	Belongs to the UPF0753 family
ETAA8_RS01650	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ETAA8_RS01655	COG1007	ATP synthesis coupled electron transport
ETAA8_RS01675	COG4797	methyltransferase
ETAA8_RS01675	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ETAA8_RS01690	COG0584	glycerophosphoryl diester phosphodiesterase
ETAA8_RS01705	COG0612	Peptidase, M16
ETAA8_RS01710	COG0456	acetyltransferase
ETAA8_RS01750	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ETAA8_RS01845	COG0723	plastoquinol--plastocyanin reductase activity
ETAA8_RS01845	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ETAA8_RS01850	COG0300	oxidoreductase activity
ETAA8_RS01870	COG0745	RESPONSE REGULATOR receiver
ETAA8_RS01890	COG0811	peptide transport
ETAA8_RS01910	COG1595	DNA-templated transcription, initiation
ETAA8_RS01925	COG0205	6-phosphofructokinase activity
ETAA8_RS01945	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ETAA8_RS01950	COG0475	glutathione-regulated potassium exporter activity
ETAA8_RS01970	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ETAA8_RS01975	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ETAA8_RS02025	COG1943	Transposase
ETAA8_RS02030	COG0113	porphobilinogen synthase activity
ETAA8_RS02050	COG1858	cytochrome C peroxidase
ETAA8_RS02055	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
ETAA8_RS02060	COG2226	methyltransferase
ETAA8_RS02065	COG1741	Belongs to the pirin family
ETAA8_RS02070	COG1335	isochorismatase
ETAA8_RS02085	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ETAA8_RS02100	COG2022	thiamine diphosphate biosynthetic process
ETAA8_RS02110	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_RS02145	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ETAA8_RS02150	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ETAA8_RS02210	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ETAA8_RS02265	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ETAA8_RS02270	COG0640	Transcriptional regulator
ETAA8_RS02275	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
ETAA8_RS02285	COG1671	Belongs to the UPF0178 family
ETAA8_RS02315	COG1418	mRNA catabolic process
ETAA8_RS02320	COG1692	metallophosphoesterase
ETAA8_RS02380	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ETAA8_RS02395	COG1695	Transcriptional regulator
ETAA8_RS02410	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ETAA8_RS02415	COG1366	Belongs to the anti-sigma-factor antagonist family
ETAA8_RS02445	COG3119	arylsulfatase activity
ETAA8_RS02460	COG2815	serine threonine protein kinase
ETAA8_RS02460	COG0515	serine threonine protein kinase
ETAA8_RS02465	COG2076	Multidrug Resistance protein
ETAA8_RS02480	COG3252	Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT
ETAA8_RS02510	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ETAA8_RS02515	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ETAA8_RS02530	COG3119	arylsulfatase activity
ETAA8_RS02535	COG3119	arylsulfatase activity
ETAA8_RS02565	COG1082	Xylose isomerase domain protein TIM barrel
ETAA8_RS02580	COG2832	Protein of unknown function (DUF454)
ETAA8_RS02615	COG1131	(ABC) transporter
ETAA8_RS02630	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ETAA8_RS02650	COG1530	ribonuclease E activity
ETAA8_RS02665	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ETAA8_RS02675	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ETAA8_RS02690	COG1361	Conserved repeat domain
ETAA8_RS02705	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ETAA8_RS02730	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_RS02765	COG0473	3-isopropylmalate dehydrogenase activity
ETAA8_RS02780	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ETAA8_RS02785	COG0318	PFAM AMP-dependent synthetase and ligase
ETAA8_RS02790	COG3119	arylsulfatase activity
ETAA8_RS02790	COG3408	Glycogen debranching enzyme
ETAA8_RS02800	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ETAA8_RS02880	COG2070	2-Nitropropane dioxygenase
ETAA8_RS02930	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ETAA8_RS02930	COG0515	serine threonine protein kinase
ETAA8_RS02955	COG2815	serine threonine protein kinase
ETAA8_RS02955	COG0515	serine threonine protein kinase
ETAA8_RS03020	COG2815	serine threonine protein kinase
ETAA8_RS03020	COG0515	serine threonine protein kinase
ETAA8_RS03035	COG1174	glycine betaine transport
ETAA8_RS03040	COG1125	glycine betaine transport
ETAA8_RS03040	COG0517	IMP dehydrogenase activity
ETAA8_RS03110	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ETAA8_RS03115	COG1058	Belongs to the CinA family
ETAA8_RS03115	COG1546	Belongs to the CinA family
ETAA8_RS03130	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ETAA8_RS03310	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ETAA8_RS03315	COG0509	glycine decarboxylation via glycine cleavage system
ETAA8_RS03325	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ETAA8_RS03360	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ETAA8_RS03430	COG2815	serine threonine protein kinase
ETAA8_RS03430	COG0515	serine threonine protein kinase
ETAA8_RS03505	COG0180	Tryptophanyl-tRNA synthetase
ETAA8_RS03520	COG0776	regulation of translation
ETAA8_RS03525	COG0727	PFAM Uncharacterised protein family (UPF0153)
ETAA8_RS03540	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ETAA8_RS03550	COG2323	membrane
ETAA8_RS03560	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ETAA8_RS03565	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ETAA8_RS03570	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ETAA8_RS03585	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
ETAA8_RS03605	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ETAA8_RS03620	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ETAA8_RS03630	COG1899	peptidyl-lysine modification to peptidyl-hypusine
ETAA8_RS03650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ETAA8_RS03655	COG1309	transcriptional regulator
ETAA8_RS03660	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ETAA8_RS03725	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ETAA8_RS03740	COG1858	cytochrome C peroxidase
ETAA8_RS03770	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ETAA8_RS03780	COG4948	Mandelate Racemase Muconate Lactonizing
ETAA8_RS03805	COG1131	(ABC) transporter
ETAA8_RS03855	COG0515	serine threonine protein kinase
ETAA8_RS03855	COG2815	serine threonine protein kinase
ETAA8_RS03865	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ETAA8_RS03885	COG1643	Atp-dependent helicase
ETAA8_RS03890	COG3852	Histidine kinase
ETAA8_RS03895	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ETAA8_RS03925	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ETAA8_RS03930	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ETAA8_RS03935	COG0243	molybdopterin cofactor binding
ETAA8_RS03940	COG0437	4 iron, 4 sulfur cluster binding
ETAA8_RS03945	COG1116	anion transmembrane transporter activity
ETAA8_RS03950	COG1116	anion transmembrane transporter activity
ETAA8_RS03955	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ETAA8_RS03960	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ETAA8_RS03970	COG2204	response regulator
ETAA8_RS03975	COG0784	Response regulator, receiver
ETAA8_RS03975	COG2198	Histidine kinase
ETAA8_RS03975	COG2205	protein histidine kinase activity
ETAA8_RS03990	COG2169	Transcriptional regulator
ETAA8_RS04005	COG0657	acetylesterase activity
ETAA8_RS04010	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ETAA8_RS04025	COG0848	biopolymer transport protein
ETAA8_RS04030	COG0811	peptide transport
ETAA8_RS04060	COG0861	Integral membrane protein TerC family
ETAA8_RS04065	COG5002	protein histidine kinase activity
ETAA8_RS04065	COG2205	protein histidine kinase activity
ETAA8_RS04065	COG0784	Response regulator, receiver
ETAA8_RS04085	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ETAA8_RS04090	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ETAA8_RS04095	COG1596	polysaccharide export
ETAA8_RS04105	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ETAA8_RS04105	COG1793	dna ligase
ETAA8_RS04110	COG1968	undecaprenyl-diphosphatase activity
ETAA8_RS04115	COG1090	epimerase
ETAA8_RS04130	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ETAA8_RS04190	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ETAA8_RS04210	COG1136	(ABC) transporter
ETAA8_RS04220	COG0151	Belongs to the GarS family
ETAA8_RS04225	COG2176	DNA-directed DNA polymerase activity
ETAA8_RS04275	COG4227	nucleotidyltransferase activity
ETAA8_RS04300	COG4974	Belongs to the 'phage' integrase family
ETAA8_RS04310	COG2255	four-way junction helicase activity
ETAA8_RS04355	COG4977	sequence-specific DNA binding
ETAA8_RS04360	COG3059	membrane
ETAA8_RS04370	COG2204	response regulator
ETAA8_RS04390	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ETAA8_RS04410	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ETAA8_RS04460	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ETAA8_RS04505	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ETAA8_RS04685	COG3622	Belongs to the hyi family
ETAA8_RS04695	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ETAA8_RS04705	COG2378	regulation of single-species biofilm formation
ETAA8_RS04730	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ETAA8_RS04770	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ETAA8_RS04780	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ETAA8_RS04795	COG0546	phosphoglycolate phosphatase activity
ETAA8_RS04810	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
ETAA8_RS04830	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ETAA8_RS04840	COG2204	response regulator
ETAA8_RS04850	COG0165	Argininosuccinate lyase
ETAA8_RS04860	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ETAA8_RS04870	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ETAA8_RS04890	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ETAA8_RS04910	COG2814	Major facilitator Superfamily
ETAA8_RS04920	COG4964	Belongs to the GSP D family
ETAA8_RS04935	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ETAA8_RS04955	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ETAA8_RS05010	COG1448	Aminotransferase
ETAA8_RS05020	COG2706	6-phosphogluconolactonase activity
ETAA8_RS05100	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ETAA8_RS05120	COG2363	Small membrane protein
ETAA8_RS05130	COG0163	prenyltransferase activity
ETAA8_RS05135	COG2226	methyltransferase
ETAA8_RS05180	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ETAA8_RS05185	COG1053	succinate dehydrogenase
ETAA8_RS05190	COG2009	succinate dehydrogenase
ETAA8_RS05240	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ETAA8_RS05245	COG0577	efflux transmembrane transporter activity
ETAA8_RS05245	COG1136	(ABC) transporter
ETAA8_RS05255	COG3875	lactate racemase activity
ETAA8_RS05270	COG0693	protein deglycase activity
ETAA8_RS05290	COG2261	transglycosylase associated protein
ETAA8_RS05345	COG0745	RESPONSE REGULATOR receiver
ETAA8_RS05365	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ETAA8_RS05380	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ETAA8_RS05390	COG0571	ribonuclease III activity
ETAA8_RS05410	COG0673	inositol 2-dehydrogenase activity
ETAA8_RS05420	COG4964	Belongs to the GSP D family
ETAA8_RS05445	COG0028	Belongs to the TPP enzyme family
ETAA8_RS05470	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ETAA8_RS05475	COG3622	Belongs to the hyi family
ETAA8_RS05505	COG0284	orotidine-5'-phosphate decarboxylase activity
ETAA8_RS05510	COG0742	ribosomal rna small subunit methyltransferase
ETAA8_RS05540	COG2304	oxidoreductase activity
ETAA8_RS05575	COG5002	protein histidine kinase activity
ETAA8_RS05585	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ETAA8_RS05590	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ETAA8_RS05600	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ETAA8_RS05615	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_RS05620	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_RS05625	COG0488	(ABC) transporter
ETAA8_RS05635	COG0521	Mo-molybdopterin cofactor biosynthetic process
ETAA8_RS05665	COG0525	valine-tRNA ligase activity
ETAA8_RS05695	COG0653	protein targeting
ETAA8_RS05705	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ETAA8_RS05710	COG0052	Belongs to the universal ribosomal protein uS2 family
ETAA8_RS05725	COG1131	(ABC) transporter
ETAA8_RS05780	COG3437	response regulator, receiver
ETAA8_RS05785	COG0004	ammonium transporteR
ETAA8_RS05800	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ETAA8_RS05805	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ETAA8_RS05845	COG0183	Belongs to the thiolase family
ETAA8_RS05850	COG1250	3-hydroxyacyl-CoA dehydrogenase
ETAA8_RS05850	COG1024	Enoyl-CoA hydratase
ETAA8_RS05875	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ETAA8_RS05880	COG1459	type II secretion system
ETAA8_RS05885	COG2165	general secretion pathway protein
ETAA8_RS05920	COG1450	Type ii and iii secretion system protein
ETAA8_RS05935	COG2204	response regulator
ETAA8_RS05940	COG5487	UPF0391 membrane protein
ETAA8_RS05945	COG3237	CsbD-like
ETAA8_RS05955	COG0783	Belongs to the Dps family
ETAA8_RS05970	COG0667	Aldo Keto reductase
ETAA8_RS05975	COG1136	(ABC) transporter
ETAA8_RS05995	COG2140	Oxalate decarboxylase
ETAA8_RS06000	COG0783	Belongs to the Dps family
ETAA8_RS06015	COG2815	serine threonine protein kinase
ETAA8_RS06015	COG0515	serine threonine protein kinase
ETAA8_RS06025	COG2814	Major facilitator Superfamily
ETAA8_RS06035	COG0588	phosphoglycerate mutase activity
ETAA8_RS06060	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ETAA8_RS06065	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_RS06080	COG3119	arylsulfatase activity
ETAA8_RS06085	COG3119	arylsulfatase activity
ETAA8_RS06120	COG0477	Major facilitator Superfamily
ETAA8_RS06190	COG2205	protein histidine kinase activity
ETAA8_RS06200	COG5002	protein histidine kinase activity
ETAA8_RS06210	COG2204	response regulator
ETAA8_RS06220	COG0148	phosphopyruvate hydratase activity
ETAA8_RS06225	COG0148	phosphopyruvate hydratase activity
ETAA8_RS06250	COG2378	regulation of single-species biofilm formation
ETAA8_RS06260	COG0515	serine threonine protein kinase
ETAA8_RS06260	COG2815	serine threonine protein kinase
ETAA8_RS06285	COG1484	DNA-dependent DNA replication
ETAA8_RS06315	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA8_RS06385	COG0668	transmembrane transport
ETAA8_RS06400	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ETAA8_RS06410	COG3119	arylsulfatase activity
ETAA8_RS06455	COG3344	reverse transcriptase
ETAA8_RS06515	COG0210	DNA helicase
ETAA8_RS06530	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ETAA8_RS06555	COG0247	lactate metabolic process
ETAA8_RS06565	COG0733	neurotransmitter:sodium symporter activity
ETAA8_RS06570	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ETAA8_RS06575	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ETAA8_RS06590	COG0205	6-phosphofructokinase activity
ETAA8_RS06605	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ETAA8_RS06645	COG3458	cephalosporin-C deacetylase activity
ETAA8_RS06660	COG0673	inositol 2-dehydrogenase activity
ETAA8_RS06670	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ETAA8_RS06695	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ETAA8_RS06705	COG0564	pseudouridine synthase activity
ETAA8_RS06715	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ETAA8_RS06725	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ETAA8_RS06730	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ETAA8_RS06765	COG0515	serine threonine protein kinase
ETAA8_RS06765	COG2815	serine threonine protein kinase
ETAA8_RS06780	COG1073	alpha beta
ETAA8_RS06800	COG2096	Adenosyltransferase
ETAA8_RS06810	COG2738	Putative neutral zinc metallopeptidase
ETAA8_RS06825	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ETAA8_RS06830	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_RS06835	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ETAA8_RS06840	COG5285	phytanoyl-CoA dioxygenase
ETAA8_RS06850	COG1970	mechanosensitive ion channel activity
ETAA8_RS06855	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ETAA8_RS06860	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
ETAA8_RS06875	COG1131	(ABC) transporter
ETAA8_RS06880	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ETAA8_RS06890	COG3012	SEC-C Motif Domain Protein
ETAA8_RS06905	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ETAA8_RS06975	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ETAA8_RS06985	COG4191	Histidine kinase
ETAA8_RS06995	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ETAA8_RS07000	COG0247	lactate metabolic process
ETAA8_RS07005	COG1139	Iron-sulfur cluster binding protein
ETAA8_RS07010	COG1556	Lactate utilization protein
ETAA8_RS07015	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ETAA8_RS07020	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ETAA8_RS07025	COG3608	succinylglutamate desuccinylase aspartoacylase
ETAA8_RS07025	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ETAA8_RS07030	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
ETAA8_RS07040	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ETAA8_RS07045	COG0631	protein serine/threonine phosphatase activity
ETAA8_RS07050	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ETAA8_RS07090	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ETAA8_RS07165	COG1797	cobyrinic acid a,c-diamide synthase activity
ETAA8_RS07205	COG3118	belongs to the thioredoxin family
ETAA8_RS07215	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ETAA8_RS07225	COG0626	cystathionine gamma-synthase activity
ETAA8_RS07245	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ETAA8_RS07250	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ETAA8_RS07280	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA8_RS07310	COG0717	Belongs to the dCTP deaminase family
ETAA8_RS07315	COG2814	Major facilitator Superfamily
ETAA8_RS07330	COG1045	serine acetyltransferase
ETAA8_RS07340	COG1104	cysteine desulfurase activity
ETAA8_RS07350	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ETAA8_RS07350	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ETAA8_RS07370	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ETAA8_RS07410	COG1064	alcohol dehydrogenase
ETAA8_RS07415	COG3119	arylsulfatase activity
ETAA8_RS07420	COG3119	arylsulfatase activity
ETAA8_RS07425	COG3119	arylsulfatase activity
ETAA8_RS07435	COG3119	arylsulfatase activity
ETAA8_RS07440	COG0736	holo-[acyl-carrier-protein] synthase activity
ETAA8_RS07465	COG0444	Belongs to the ABC transporter superfamily
ETAA8_RS07470	COG4608	Belongs to the ABC transporter superfamily
ETAA8_RS07490	COG0673	inositol 2-dehydrogenase activity
ETAA8_RS07495	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ETAA8_RS07500	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ETAA8_RS07510	COG0673	inositol 2-dehydrogenase activity
ETAA8_RS07535	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
ETAA8_RS07540	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ETAA8_RS07570	COG0515	serine threonine protein kinase
ETAA8_RS07615	COG1073	alpha beta
ETAA8_RS07650	COG1253	flavin adenine dinucleotide binding
ETAA8_RS07670	COG1716	ATPase activity
ETAA8_RS07680	COG3264	Mechanosensitive ion channel
ETAA8_RS07680	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
ETAA8_RS07685	COG0598	Magnesium transport protein CorA
ETAA8_RS07690	COG0720	synthase
ETAA8_RS07695	COG0488	(ABC) transporter
ETAA8_RS07735	COG2234	aminopeptidase activity
ETAA8_RS07745	COG4974	Belongs to the 'phage' integrase family
ETAA8_RS07770	COG0732	type I restriction modification DNA specificity domain
ETAA8_RS07920	COG2706	6-phosphogluconolactonase activity
ETAA8_RS08010	COG0515	serine threonine protein kinase
ETAA8_RS08010	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ETAA8_RS08045	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ETAA8_RS08120	COG1484	DNA-dependent DNA replication
ETAA8_RS08135	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ETAA8_RS08165	COG2319	Wd-40 repeat
ETAA8_RS08165	COG5635	Nacht domain
ETAA8_RS08240	COG3119	arylsulfatase activity
ETAA8_RS08285	COG2217	Heavy metal translocating P-type atpase
ETAA8_RS08305	COG1484	DNA-dependent DNA replication
ETAA8_RS08320	COG4974	Belongs to the 'phage' integrase family
ETAA8_RS08365	COG1595	DNA-templated transcription, initiation
ETAA8_RS08385	COG2217	Heavy metal translocating P-type atpase
ETAA8_RS08410	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ETAA8_RS08415	COG2755	lipolytic protein G-D-S-L family
ETAA8_RS08415	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ETAA8_RS08445	COG2226	methyltransferase
ETAA8_RS08450	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ETAA8_RS08455	COG1104	cysteine desulfurase activity
ETAA8_RS08460	COG0640	Transcriptional regulator
ETAA8_RS08495	COG0477	Major facilitator Superfamily
ETAA8_RS08530	COG5433	transposase activity
ETAA8_RS08540	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA8_RS08565	COG1136	(ABC) transporter
ETAA8_RS08570	COG0577	efflux transmembrane transporter activity
ETAA8_RS08590	COG1742	UPF0060 membrane protein
ETAA8_RS08625	COG0515	serine threonine protein kinase
ETAA8_RS08625	COG2815	serine threonine protein kinase
ETAA8_RS08645	COG0515	serine threonine protein kinase
ETAA8_RS08645	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ETAA8_RS08680	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ETAA8_RS08705	COG0582	viral genome integration into host DNA
ETAA8_RS08710	COG0745	RESPONSE REGULATOR receiver
ETAA8_RS08715	COG2205	protein histidine kinase activity
ETAA8_RS08720	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
ETAA8_RS08725	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ETAA8_RS08730	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ETAA8_RS08750	COG2239	Acts as a magnesium transporter
ETAA8_RS08770	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ETAA8_RS08780	COG4191	Histidine kinase
ETAA8_RS08785	COG2204	response regulator
ETAA8_RS08815	COG0205	6-phosphofructokinase activity
ETAA8_RS08835	COG2186	Transcriptional regulator
ETAA8_RS08855	COG1484	DNA-dependent DNA replication
ETAA8_RS08865	COG0515	serine threonine protein kinase
ETAA8_RS08875	COG1136	(ABC) transporter
ETAA8_RS08875	COG0577	efflux transmembrane transporter activity
ETAA8_RS08905	COG3119	arylsulfatase activity
ETAA8_RS08925	COG0124	histidyl-tRNA synthetase
ETAA8_RS08940	COG1194	a g-specific adenine glycosylase
ETAA8_RS08945	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ETAA8_RS08970	COG0564	pseudouridine synthase activity
ETAA8_RS08990	COG0295	cytidine deaminase activity
ETAA8_RS09005	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ETAA8_RS09015	COG0028	Belongs to the TPP enzyme family
ETAA8_RS09020	COG0659	secondary active sulfate transmembrane transporter activity
ETAA8_RS09025	COG0288	reversible hydration of carbon dioxide
ETAA8_RS09040	COG2094	Belongs to the DNA glycosylase MPG family
ETAA8_RS09105	COG0463	Glycosyl transferase, family 2
ETAA8_RS09110	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ETAA8_RS09150	COG3119	arylsulfatase activity
ETAA8_RS09155	COG1335	isochorismatase
ETAA8_RS09205	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
ETAA8_RS09210	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ETAA8_RS09245	COG1674	ftsk spoiiie
ETAA8_RS09255	COG1560	Kdo2-lipid A biosynthetic process
ETAA8_RS09270	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ETAA8_RS09285	COG0352	thiamine-phosphate diphosphorylase activity
ETAA8_RS09290	COG1136	(ABC) transporter
ETAA8_RS09295	COG4591	ABC-type transport system involved in lipoprotein release permease component
ETAA8_RS09310	COG1305	Transglutaminase-like
ETAA8_RS09320	COG4251	negative regulation of phosphorylation
ETAA8_RS09325	COG0784	Response regulator, receiver
ETAA8_RS09330	COG5002	protein histidine kinase activity
ETAA8_RS09350	COG3386	PFAM SMP-30 Gluconolaconase
ETAA8_RS09360	COG3119	arylsulfatase activity
ETAA8_RS09370	COG4166	transmembrane transport
ETAA8_RS09375	COG0601	transmembrane transport
ETAA8_RS09380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ETAA8_RS09470	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ETAA8_RS09500	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ETAA8_RS09505	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ETAA8_RS09525	COG0740	serine-type endopeptidase activity
ETAA8_RS09530	COG0740	serine-type endopeptidase activity
ETAA8_RS09545	COG0004	ammonium transporteR
ETAA8_RS09555	COG0596	Alpha beta hydrolase
ETAA8_RS09585	COG0719	Fe-S assembly protein
ETAA8_RS09600	COG0719	Fe-S assembly protein
ETAA8_RS09605	COG0396	ATPase activity
ETAA8_RS09610	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ETAA8_RS09650	COG4968	Prepilin-type N-terminal cleavage methylation domain
ETAA8_RS09665	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ETAA8_RS09670	COG1449	Belongs to the glycosyl hydrolase 57 family
ETAA8_RS09695	COG0577	efflux transmembrane transporter activity
ETAA8_RS09695	COG1136	(ABC) transporter
ETAA8_RS09705	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ETAA8_RS09710	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ETAA8_RS09755	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ETAA8_RS09765	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ETAA8_RS09780	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ETAA8_RS09785	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ETAA8_RS09790	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ETAA8_RS09805	COG1582	Flagellar protein (FlbD)
ETAA8_RS09810	COG1749	Flagellar hook protein flgE
ETAA8_RS09815	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ETAA8_RS09835	COG1157	protein secretion by the type III secretion system
ETAA8_RS09845	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ETAA8_RS09855	COG1677	Flagellar hook-basal body complex protein FliE
ETAA8_RS09865	COG1815	bacterial-type flagellum-dependent cell motility
ETAA8_RS09870	COG2204	response regulator
ETAA8_RS09875	COG3852	Histidine kinase
ETAA8_RS09900	COG0039	L-malate dehydrogenase activity
ETAA8_RS09905	COG3228	Belongs to the MtfA family
ETAA8_RS09920	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ETAA8_RS09950	COG0367	asparagine synthase
ETAA8_RS09955	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ETAA8_RS09985	COG3541	Predicted nucleotidyltransferase
ETAA8_RS09995	COG0347	Belongs to the P(II) protein family
ETAA8_RS10080	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ETAA8_RS10110	COG3118	belongs to the thioredoxin family
ETAA8_RS10140	COG1450	Type ii and iii secretion system protein
ETAA8_RS10200	COG0735	belongs to the Fur family
ETAA8_RS10205	COG0523	cobalamin synthesis protein
ETAA8_RS10225	COG0673	inositol 2-dehydrogenase activity
ETAA8_RS10255	COG0784	Response regulator, receiver
ETAA8_RS10255	COG5002	protein histidine kinase activity
ETAA8_RS10260	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
ETAA8_RS10265	COG4251	negative regulation of phosphorylation
ETAA8_RS10270	COG5002	protein histidine kinase activity
ETAA8_RS10310	COG3119	arylsulfatase activity
ETAA8_RS10320	COG2124	cytochrome p450
ETAA8_RS10325	COG2610	gluconate transmembrane transporter activity
ETAA8_RS10335	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ETAA8_RS10340	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_RS10365	COG3119	arylsulfatase activity
ETAA8_RS10370	COG3119	arylsulfatase activity
ETAA8_RS10375	COG3119	arylsulfatase activity
ETAA8_RS10420	COG3119	arylsulfatase activity
ETAA8_RS10430	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ETAA8_RS10435	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ETAA8_RS10445	COG4585	Histidine kinase
ETAA8_RS10450	COG2197	response regulator
ETAA8_RS10455	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ETAA8_RS10460	COG1595	DNA-templated transcription, initiation
ETAA8_RS10465	COG0515	serine threonine protein kinase
ETAA8_RS10465	COG2815	serine threonine protein kinase
ETAA8_RS10500	COG1007	ATP synthesis coupled electron transport
ETAA8_RS10515	COG0713	ATP synthesis coupled electron transport
ETAA8_RS10520	COG0839	Belongs to the complex I subunit 6 family
ETAA8_RS10525	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ETAA8_RS10530	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ETAA8_RS10535	COG1034	ATP synthesis coupled electron transport
ETAA8_RS10545	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
ETAA8_RS10550	COG0649	NAD binding
ETAA8_RS10555	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ETAA8_RS10560	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ETAA8_RS10565	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ETAA8_RS10575	COG1363	Peptidase, m42
ETAA8_RS10580	COG1091	dTDP-4-dehydrorhamnose reductase activity
ETAA8_RS10585	COG2264	protein methyltransferase activity
ETAA8_RS10595	COG2501	S4 domain
ETAA8_RS10630	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETAA8_RS10650	COG0438	transferase activity, transferring glycosyl groups
ETAA8_RS10665	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ETAA8_RS10670	COG0287	Prephenate dehydrogenase
ETAA8_RS10740	COG0366	Alpha amylase catalytic
ETAA8_RS10785	COG0667	Aldo Keto reductase
ETAA8_RS10930	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ETAA8_RS10955	COG1506	peptidase
ETAA8_RS10955	COG0823	Involved in the tonB-independent uptake of proteins
ETAA8_RS10960	COG0574	Belongs to the PEP-utilizing enzyme family
ETAA8_RS10960	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ETAA8_RS10975	COG0543	2 iron, 2 sulfur cluster binding
ETAA8_RS10980	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ETAA8_RS10985	COG0427	acetyl-CoA hydrolase
ETAA8_RS11010	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
ETAA8_RS11025	COG0309	Hydrogenase expression formation protein (HypE)
ETAA8_RS11035	COG0443	Heat shock 70 kDa protein
ETAA8_RS11045	COG1959	2 iron, 2 sulfur cluster binding
ETAA8_RS11050	COG1151	hydroxylamine reductase activity
ETAA8_RS11065	COG2423	ornithine cyclodeaminase activity
ETAA8_RS11070	COG2326	polyphosphate kinase activity
ETAA8_RS11090	COG0058	SHG alpha-glucan phosphorylase activity
ETAA8_RS11140	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ETAA8_RS11200	COG3119	arylsulfatase activity
ETAA8_RS11205	COG0657	acetylesterase activity
ETAA8_RS11220	COG1754	DNA topoisomerase type I activity
ETAA8_RS11220	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ETAA8_RS11265	COG0653	protein targeting
ETAA8_RS11275	COG0443	Heat shock 70 kDa protein
ETAA8_RS11290	COG1082	Xylose isomerase domain protein TIM barrel
ETAA8_RS11305	COG0745	RESPONSE REGULATOR receiver
ETAA8_RS11340	COG0657	acetylesterase activity
ETAA8_RS11340	COG2755	lipolytic protein G-D-S-L family
ETAA8_RS11360	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
ETAA8_RS11360	COG0493	'glutamate synthase
ETAA8_RS11365	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ETAA8_RS11380	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
ETAA8_RS11465	COG0454	-acetyltransferase
ETAA8_RS11505	COG0204	Acyl-transferase
ETAA8_RS11505	COG0318	PFAM AMP-dependent synthetase and ligase
ETAA8_RS11510	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ETAA8_RS11515	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ETAA8_RS11520	COG1722	exodeoxyribonuclease VII activity
ETAA8_RS11525	COG1570	exodeoxyribonuclease VII activity
ETAA8_RS11530	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ETAA8_RS11535	COG1331	Highly conserved protein containing a thioredoxin domain
ETAA8_RS11540	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ETAA8_RS11545	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ETAA8_RS11545	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ETAA8_RS11585	COG1136	(ABC) transporter
ETAA8_RS11585	COG0577	efflux transmembrane transporter activity
ETAA8_RS11595	COG3344	reverse transcriptase
ETAA8_RS11635	COG0488	(ABC) transporter
ETAA8_RS11645	COG0726	polysaccharide deacetylase
ETAA8_RS11740	COG1505	serine-type exopeptidase activity
ETAA8_RS11755	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ETAA8_RS11780	COG1691	(AIR) carboxylase
ETAA8_RS11785	COG0137	argininosuccinate synthase activity
ETAA8_RS11790	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ETAA8_RS11820	COG0723	plastoquinol--plastocyanin reductase activity
ETAA8_RS11835	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ETAA8_RS11835	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ETAA8_RS11845	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ETAA8_RS11855	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ETAA8_RS11880	COG0543	2 iron, 2 sulfur cluster binding
ETAA8_RS11895	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ETAA8_RS11905	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ETAA8_RS11930	COG0423	glycine-tRNA ligase activity
ETAA8_RS11935	COG2045	Belongs to the ComB family
ETAA8_RS11940	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ETAA8_RS11945	COG1597	lipid kinase activity
ETAA8_RS11955	COG1136	(ABC) transporter
ETAA8_RS11970	COG0424	maF-like protein
ETAA8_RS11990	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETAA8_RS11995	COG0681	Belongs to the peptidase S26 family
ETAA8_RS12000	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ETAA8_RS12005	COG4948	Mandelate Racemase Muconate Lactonizing
ETAA8_RS12040	COG0436	Aminotransferase
ETAA8_RS12060	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ETAA8_RS12085	COG0165	Argininosuccinate lyase
ETAA8_RS12110	COG0488	(ABC) transporter
ETAA8_RS12135	COG2133	pyrroloquinoline quinone binding
ETAA8_RS12145	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_RS12175	COG0657	acetylesterase activity
ETAA8_RS12180	COG0006	proline dipeptidase activity
ETAA8_RS12195	COG0436	Aminotransferase
ETAA8_RS12210	COG1073	alpha beta
ETAA8_RS12215	COG2890	protein-(glutamine-N5) methyltransferase activity
ETAA8_RS12250	COG5002	protein histidine kinase activity
ETAA8_RS12285	COG1490	D-aminoacyl-tRNA deacylase activity
ETAA8_RS12320	COG0038	chloride channel
ETAA8_RS12325	COG0825	malonyl-CoA metabolic process
ETAA8_RS12330	COG0515	serine threonine protein kinase
ETAA8_RS12330	COG2815	serine threonine protein kinase
ETAA8_RS12335	COG0167	dihydroorotate dehydrogenase activity
ETAA8_RS12345	COG0745	RESPONSE REGULATOR receiver
ETAA8_RS12380	COG0604	alcohol dehydrogenase
ETAA8_RS12400	COG1040	competence protein
ETAA8_RS12415	COG0101	tRNA pseudouridine synthase activity
ETAA8_RS12450	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ETAA8_RS12460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA8_RS12460	COG0706	membrane insertase activity
ETAA8_RS12465	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ETAA8_RS12470	COG0657	acetylesterase activity
ETAA8_RS12475	COG3119	arylsulfatase activity
ETAA8_RS12480	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ETAA8_RS12495	COG0673	inositol 2-dehydrogenase activity
ETAA8_RS12525	COG2189	Belongs to the N(4) N(6)-methyltransferase family
ETAA8_RS12530	COG0233	cytoplasmic translational termination
ETAA8_RS12535	COG1058	Belongs to the CinA family
ETAA8_RS12535	COG1546	Belongs to the CinA family
ETAA8_RS12540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ETAA8_RS12580	COG3119	arylsulfatase activity
ETAA8_RS12605	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ETAA8_RS12610	COG0297	glycogen (starch) synthase activity
ETAA8_RS12635	COG0514	ATP-dependent DNA helicase (RecQ)
ETAA8_RS12650	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ETAA8_RS12665	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ETAA8_RS12670	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ETAA8_RS12705	COG0430	RNA-3'-phosphate cyclase activity
ETAA8_RS12715	COG2815	serine threonine protein kinase
ETAA8_RS12715	COG0515	serine threonine protein kinase
ETAA8_RS12720	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ETAA8_RS12765	COG3243	poly(R)-hydroxyalkanoic acid synthase
ETAA8_RS12780	COG0443	Heat shock 70 kDa protein
ETAA8_RS12810	COG0811	peptide transport
ETAA8_RS12815	COG2205	protein histidine kinase activity
ETAA8_RS12830	COG0517	IMP dehydrogenase activity
ETAA8_RS12830	COG0516	GMP reductase activity
ETAA8_RS12880	COG0564	pseudouridine synthase activity
ETAA8_RS12905	COG0437	4 iron, 4 sulfur cluster binding
ETAA8_RS12930	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
ETAA8_RS12935	COG1229	Formylmethanofuran dehydrogenase subunit A
ETAA8_RS12955	COG1131	(ABC) transporter
ETAA8_RS13000	COG0268	Binds directly to 16S ribosomal RNA
ETAA8_RS13060	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ETAA8_RS13065	COG1321	iron dependent repressor
ETAA8_RS13065	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ETAA8_RS13070	COG1121	(ABC) transporter
ETAA8_RS13075	COG0803	Belongs to the bacterial solute-binding protein 9 family
ETAA8_RS13080	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ETAA8_RS13095	COG0463	Glycosyl transferase, family 2
ETAA8_RS13100	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ETAA8_RS13115	COG0628	permease
ETAA8_RS13130	COG0584	glycerophosphoryl diester phosphodiesterase
ETAA8_RS13135	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ETAA8_RS13165	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ETAA8_RS13210	COG0159	tryptophan synthase activity
ETAA8_RS13215	COG0133	tryptophan synthase activity
ETAA8_RS13230	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ETAA8_RS13235	COG0275	rRNA processing
ETAA8_RS13260	COG0019	diaminopimelate decarboxylase activity
ETAA8_RS13265	COG0318	PFAM AMP-dependent synthetase and ligase
ETAA8_RS13285	COG0405	Gamma-glutamyltransferase
ETAA8_RS13295	COG1994	Peptidase M50
ETAA8_RS13335	COG1136	(ABC) transporter
ETAA8_RS13340	COG0577	efflux transmembrane transporter activity
ETAA8_RS13370	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ETAA8_RS13405	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ETAA8_RS13405	COG0237	dephospho-CoA kinase activity
ETAA8_RS13410	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ETAA8_RS13415	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ETAA8_RS13425	COG2195	Cleaves the N-terminal amino acid of tripeptides
ETAA8_RS13445	COG4948	Mandelate Racemase Muconate Lactonizing
ETAA8_RS13455	COG4948	Mandelate Racemase Muconate Lactonizing
ETAA8_RS13505	COG0805	protein transport
ETAA8_RS13510	COG1482	cell wall glycoprotein biosynthetic process
ETAA8_RS13520	COG0830	nickel cation binding
ETAA8_RS13535	COG0501	Belongs to the peptidase M48B family
ETAA8_RS13540	COG3437	response regulator, receiver
ETAA8_RS13540	COG2205	protein histidine kinase activity
ETAA8_RS13540	COG4999	Histidine kinase
ETAA8_RS13540	COG3850	Histidine kinase
ETAA8_RS13590	COG3852	Histidine kinase
ETAA8_RS13595	COG0488	(ABC) transporter
ETAA8_RS13615	COG3209	COG3209 Rhs family protein
ETAA8_RS13625	COG1484	DNA-dependent DNA replication
ETAA8_RS13700	COG2815	serine threonine protein kinase
ETAA8_RS13700	COG0515	serine threonine protein kinase
ETAA8_RS13715	COG1595	DNA-templated transcription, initiation
ETAA8_RS13755	COG1164	Oligoendopeptidase f
ETAA8_RS13825	COG1214	PFAM Peptidase M22, glycoprotease
ETAA8_RS13835	COG4636	protein conserved in cyanobacteria
ETAA8_RS13875	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ETAA8_RS13880	COG0440	acetolactate synthase activity
ETAA8_RS13890	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ETAA8_RS13895	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ETAA8_RS13900	COG0154	amidase activity
ETAA8_RS13905	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ETAA8_RS13910	COG4636	protein conserved in cyanobacteria
ETAA8_RS14030	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ETAA8_RS14040	COG4999	Histidine kinase
ETAA8_RS14040	COG3850	Histidine kinase
ETAA8_RS14040	COG2205	protein histidine kinase activity
ETAA8_RS14040	COG3437	response regulator, receiver
ETAA8_RS14045	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ETAA8_RS14070	COG1132	(ABC) transporter
ETAA8_RS14075	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ETAA8_RS14075	COG0189	ligase activity
ETAA8_RS14085	COG0531	amino acid
ETAA8_RS14090	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ETAA8_RS14095	COG0509	glycine decarboxylation via glycine cleavage system
ETAA8_RS14100	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ETAA8_RS14105	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ETAA8_RS14110	COG0095	Lipoate-protein ligase
ETAA8_RS14120	COG1595	DNA-templated transcription, initiation
ETAA8_RS14150	COG1254	Belongs to the acylphosphatase family
ETAA8_RS14160	COG0564	pseudouridine synthase activity
ETAA8_RS14190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA8_RS14195	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ETAA8_RS14200	COG0346	lactoylglutathione lyase activity
ETAA8_RS14220	COG4589	Belongs to the CDS family
ETAA8_RS14270	COG0657	acetylesterase activity
ETAA8_RS14295	COG0148	phosphopyruvate hydratase activity
ETAA8_RS14305	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA8_RS14315	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ETAA8_RS14320	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ETAA8_RS14330	COG4993	Dehydrogenase
ETAA8_RS14335	COG3119	arylsulfatase activity
ETAA8_RS14350	COG3119	arylsulfatase activity
ETAA8_RS14365	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ETAA8_RS14375	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ETAA8_RS14375	COG2755	lipolytic protein G-D-S-L family
ETAA8_RS14400	COG1063	alcohol dehydrogenase
ETAA8_RS14460	COG0542	response to heat
ETAA8_RS14465	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_RS14480	COG0714	Associated with various cellular activities
ETAA8_RS14535	COG5564	TIM-barrel signal transduction protein
ETAA8_RS14540	COG4762	Protein conserved in bacteria
ETAA8_RS14590	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ETAA8_RS14635	COG0659	secondary active sulfate transmembrane transporter activity
ETAA8_RS14645	COG1012	belongs to the aldehyde dehydrogenase family
ETAA8_RS14650	COG0438	transferase activity, transferring glycosyl groups
ETAA8_RS14655	COG0438	transferase activity, transferring glycosyl groups
ETAA8_RS14680	COG3408	Glycogen debranching enzyme
ETAA8_RS14680	COG3119	arylsulfatase activity
ETAA8_RS14715	COG2319	Wd-40 repeat
ETAA8_RS14750	COG0745	RESPONSE REGULATOR receiver
ETAA8_RS14760	COG0039	L-malate dehydrogenase activity
ETAA8_RS14775	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ETAA8_RS14780	COG2183	response to ionizing radiation
ETAA8_RS14780	COG0539	negative regulation of cytoplasmic translation
ETAA8_RS14815	COG0587	DNA-directed DNA polymerase activity
ETAA8_RS14835	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ETAA8_RS14840	COG0321	lipoyl(octanoyl) transferase activity
ETAA8_RS14870	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ETAA8_RS14880	COG4537	Required for transformation and DNA binding
ETAA8_RS14890	COG1858	cytochrome C peroxidase
ETAA8_RS14915	COG0432	Pfam Uncharacterised protein family UPF0047
ETAA8_RS14925	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ETAA8_RS14930	COG0483	inositol monophosphate 1-phosphatase activity
ETAA8_RS14945	COG0459	protein refolding
ETAA8_RS14950	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ETAA8_RS14960	COG0556	nucleotide-excision repair
ETAA8_RS14980	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_RS14985	COG0300	oxidoreductase activity
ETAA8_RS14985	COG3321	synthase
ETAA8_RS14985	COG4221	oxidoreductase activity
ETAA8_RS14985	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ETAA8_RS14990	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ETAA8_RS14990	COG3320	Male sterility
ETAA8_RS14995	COG3119	arylsulfatase activity
ETAA8_RS15060	COG0071	Belongs to the small heat shock protein (HSP20) family
ETAA8_RS15095	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
ETAA8_RS15100	COG5002	protein histidine kinase activity
ETAA8_RS15125	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ETAA8_RS15130	COG0662	Cupin 2, conserved barrel domain protein
ETAA8_RS15135	COG1272	protein, Hemolysin III
ETAA8_RS15140	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ETAA8_RS15145	COG0628	permease
ETAA8_RS15175	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ETAA8_RS15180	COG2205	protein histidine kinase activity
ETAA8_RS15180	COG0784	Response regulator, receiver
ETAA8_RS15195	COG0714	Associated with various cellular activities
ETAA8_RS15240	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA8_RS15250	COG1834	amidinotransferase
ETAA8_RS15305	COG0024	Methionine aminopeptidase
ETAA8_RS15365	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ETAA8_RS15380	COG2226	methyltransferase
ETAA8_RS15385	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ETAA8_RS15395	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ETAA8_RS15400	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ETAA8_RS15465	COG0463	Glycosyl transferase, family 2
ETAA8_RS15520	COG1271	oxidase subunit
ETAA8_RS15575	COG4968	Prepilin-type N-terminal cleavage methylation domain
ETAA8_RS15585	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ETAA8_RS15595	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ETAA8_RS15600	COG0494	nUDIX hydrolase
ETAA8_RS15605	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ETAA8_RS15615	COG0673	inositol 2-dehydrogenase activity
ETAA8_RS15630	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_RS15650	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ETAA8_RS15655	COG1078	dGTPase activity
ETAA8_RS15690	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ETAA8_RS15695	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ETAA8_RS15725	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ETAA8_RS15735	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ETAA8_RS15740	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ETAA8_RS15745	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ETAA8_RS15750	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ETAA8_RS15825	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ETAA8_RS15825	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ETAA8_RS15895	COG1335	isochorismatase
ETAA8_RS15905	COG1252	NADH dehydrogenase
ETAA8_RS15930	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ETAA8_RS15935	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ETAA8_RS15950	COG2010	Cytochrome c
ETAA8_RS15960	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ETAA8_RS15975	COG0574	Belongs to the PEP-utilizing enzyme family
ETAA8_RS15975	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ETAA8_RS16030	COG0617	tRNA 3'-terminal CCA addition
ETAA8_RS16060	COG0436	Aminotransferase
ETAA8_RS16065	COG0505	Belongs to the CarA family
ETAA8_RS16085	COG0745	RESPONSE REGULATOR receiver
ETAA8_RS16115	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ETAA8_RS16130	COG0539	negative regulation of cytoplasmic translation
ETAA8_RS16130	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ETAA8_RS16150	COG2066	Belongs to the glutaminase family
ETAA8_RS16175	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ETAA8_RS16180	COG0590	tRNA wobble adenosine to inosine editing
ETAA8_RS16185	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ETAA8_RS16190	COG2080	2 iron, 2 sulfur cluster binding
ETAA8_RS16215	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ETAA8_RS16230	COG0584	glycerophosphoryl diester phosphodiesterase
ETAA8_RS16235	COG0456	acetyltransferase
ETAA8_RS16245	COG1404	Belongs to the peptidase S8 family
ETAA8_RS16255	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ETAA8_RS16260	COG3386	PFAM SMP-30 Gluconolaconase
ETAA8_RS16265	COG2205	protein histidine kinase activity
ETAA8_RS16265	COG0784	Response regulator, receiver
ETAA8_RS16270	COG3527	Alpha-acetolactate decarboxylase
ETAA8_RS16290	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ETAA8_RS16310	COG2815	serine threonine protein kinase
ETAA8_RS16310	COG0515	serine threonine protein kinase
ETAA8_RS16355	COG1505	serine-type exopeptidase activity
ETAA8_RS16390	COG0438	transferase activity, transferring glycosyl groups
ETAA8_RS16395	COG0275	rRNA processing
ETAA8_RS16420	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ETAA8_RS16430	COG3253	May function as heme-dependent peroxidase
ETAA8_RS16445	COG3119	arylsulfatase activity
ETAA8_RS16485	COG0673	inositol 2-dehydrogenase activity
ETAA8_RS16500	COG3459	Glycosyltransferase 36 associated
ETAA8_RS16515	COG4191	Histidine kinase
ETAA8_RS16520	COG2204	response regulator
ETAA8_RS16560	COG2719	SpoVR family
ETAA8_RS16565	COG2718	Belongs to the UPF0229 family
ETAA8_RS16570	COG2766	serine protein kinase
ETAA8_RS16575	COG0445	tRNA wobble uridine modification
ETAA8_RS16580	COG2217	Heavy metal translocating P-type atpase
ETAA8_RS16595	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ETAA8_RS16600	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ETAA8_RS16640	COG2815	serine threonine protein kinase
ETAA8_RS16640	COG0515	serine threonine protein kinase
ETAA8_RS16665	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ETAA8_RS16670	COG0406	alpha-ribazole phosphatase activity
ETAA8_RS16675	COG0673	inositol 2-dehydrogenase activity
ETAA8_RS16720	COG0275	rRNA processing
ETAA8_RS16725	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ETAA8_RS16755	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ETAA8_RS16760	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ETAA8_RS16785	COG0604	alcohol dehydrogenase
ETAA8_RS16790	COG3118	belongs to the thioredoxin family
ETAA8_RS16795	COG0714	Associated with various cellular activities
ETAA8_RS16830	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ETAA8_RS16835	COG0793	Belongs to the peptidase S41A family
ETAA8_RS16875	COG1597	lipid kinase activity
ETAA8_RS16875	COG1803	Methylglyoxal synthase
ETAA8_RS16880	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ETAA8_RS16900	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ETAA8_RS16905	COG0698	ribose 5-phosphate isomerase
ETAA8_RS16935	COG0006	proline dipeptidase activity
ETAA8_RS16945	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ETAA8_RS16955	COG3685	Protein conserved in bacteria
ETAA8_RS16960	COG1054	Belongs to the UPF0176 family
ETAA8_RS16970	COG1070	Carbohydrate kinase
ETAA8_RS16980	COG0357	Ribosomal RNA small subunit methyltransferase G
ETAA8_RS16990	COG0412	Dienelactone hydrolase
ETAA8_RS17110	COG0457	Tetratricopeptide repeat
ETAA8_RS17110	COG0515	serine threonine protein kinase
ETAA8_RS17170	COG0084	hydrolase, TatD family'
ETAA8_RS17180	COG1007	ATP synthesis coupled electron transport
ETAA8_RS17195	COG0713	ATP synthesis coupled electron transport
ETAA8_RS17200	COG0839	Belongs to the complex I subunit 6 family
ETAA8_RS17205	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ETAA8_RS17230	COG2198	Histidine kinase
ETAA8_RS17230	COG0643	Histidine kinase
ETAA8_RS17240	COG4941	Belongs to the sigma-70 factor family
ETAA8_RS17245	COG3795	YCII-related domain
ETAA8_RS17250	COG3795	YCII-related domain
ETAA8_RS17255	COG3795	YCII-related domain
ETAA8_RS17295	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_RS17300	COG3540	Alkaline phosphatase
ETAA8_RS17305	COG0347	Belongs to the P(II) protein family
ETAA8_RS17330	COG0582	viral genome integration into host DNA
ETAA8_RS17360	COG1475	DNA binding
ETAA8_RS17420	COG0446	pyridine nucleotide-disulphide oxidoreductase
ETAA8_RS17425	COG2226	methyltransferase
ETAA8_RS17430	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ETAA8_RS17455	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ETAA8_RS17470	COG3119	arylsulfatase activity
ETAA8_RS17475	COG0596	Alpha beta hydrolase
ETAA8_RS17480	COG1942	4-Oxalocrotonate Tautomerase
ETAA8_RS17490	COG1764	response to oxidative stress
ETAA8_RS17495	COG1902	pentaerythritol trinitrate reductase activity
ETAA8_RS17505	COG0563	adenylate kinase activity
ETAA8_RS17520	COG1233	COG1233 Phytoene dehydrogenase and related
ETAA8_RS17540	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
ETAA8_RS17555	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ETAA8_RS17595	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ETAA8_RS17730	COG0303	'Molybdopterin
ETAA8_RS17755	COG1674	ftsk spoiiie
ETAA8_RS17755	COG4980	gas vesicle protein
ETAA8_RS17760	COG0824	Thioesterase
ETAA8_RS17765	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ETAA8_RS17770	COG0573	inorganic phosphate transmembrane transporter activity
ETAA8_RS17780	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ETAA8_RS17800	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ETAA8_RS17805	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ETAA8_RS17810	COG0750	zinc metalloprotease
ETAA8_RS17815	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ETAA8_RS17820	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ETAA8_RS17830	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ETAA8_RS17840	COG0492	ferredoxin-NADP+ reductase activity
ETAA8_RS17845	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
ETAA8_RS17850	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ETAA8_RS17860	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
ETAA8_RS17885	COG1073	alpha beta
ETAA8_RS17905	COG5285	phytanoyl-CoA dioxygenase
ETAA8_RS17930	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ETAA8_RS17955	COG0848	biopolymer transport protein
ETAA8_RS17975	COG0148	phosphopyruvate hydratase activity
ETAA8_RS17980	COG1242	4 iron, 4 sulfur cluster binding
ETAA8_RS18015	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ETAA8_RS18020	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
ETAA8_RS18025	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
ETAA8_RS18030	COG0235	Class ii aldolase
ETAA8_RS18050	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ETAA8_RS18075	COG3119	arylsulfatase activity
ETAA8_RS18110	COG0668	transmembrane transport
ETAA8_RS18155	COG0745	RESPONSE REGULATOR receiver
ETAA8_RS18165	COG1484	DNA-dependent DNA replication
ETAA8_RS18225	COG1132	(ABC) transporter
ETAA8_RS18230	COG0583	DNA-binding transcription factor activity
ETAA8_RS18240	COG1032	radical SAM domain protein
ETAA8_RS18245	COG0673	inositol 2-dehydrogenase activity
ETAA8_RS18250	COG1960	acyl-CoA dehydrogenase activity
ETAA8_RS18260	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ETAA8_RS18270	COG1162	GTPase activity
ETAA8_RS18285	COG0134	indole-3-glycerol-phosphate synthase activity
ETAA8_RS18295	COG0175	sulfate reduction
ETAA8_RS18300	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ETAA8_RS18330	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ETAA8_RS18340	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ETAA8_RS18345	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ETAA8_RS18350	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ETAA8_RS18355	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ETAA8_RS18360	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ETAA8_RS18365	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ETAA8_RS18370	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
ETAA8_RS18375	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ETAA8_RS18375	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ETAA8_RS18380	COG2815	serine threonine protein kinase
ETAA8_RS18380	COG0515	serine threonine protein kinase
ETAA8_RS18385	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ETAA8_RS18385	COG0321	lipoyl(octanoyl) transferase activity
ETAA8_RS18405	COG1234	tRNA 3'-trailer cleavage
ETAA8_RS18410	COG2183	response to ionizing radiation
ETAA8_RS18415	COG4191	Histidine kinase
ETAA8_RS18420	COG4566	intracellular signal transduction
ETAA8_RS18425	COG0237	dephospho-CoA kinase activity
ETAA8_RS18430	COG1940	carbohydrate kinase activity
ETAA8_RS18435	COG0248	Ppx GppA phosphatase
ETAA8_RS18440	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ETAA8_RS18445	COG0588	phosphoglycerate mutase activity
ETAA8_RS18475	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ETAA8_RS18480	COG2890	protein-(glutamine-N5) methyltransferase activity
ETAA8_RS18485	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ETAA8_RS18490	COG0254	rRNA binding
ETAA8_RS18495	COG0724	RNA recognition motif
ETAA8_RS18500	COG0154	amidase activity
ETAA8_RS18515	COG0586	Pfam SNARE associated Golgi protein
ETAA8_RS18520	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ETAA8_RS18535	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_RS18550	COG3437	response regulator, receiver
ETAA8_RS18550	COG3850	Histidine kinase
ETAA8_RS18550	COG4999	Histidine kinase
ETAA8_RS18550	COG2205	protein histidine kinase activity
ETAA8_RS18555	COG2205	protein histidine kinase activity
ETAA8_RS18555	COG0784	Response regulator, receiver
ETAA8_RS18590	COG1012	belongs to the aldehyde dehydrogenase family
ETAA8_RS18665	COG1450	Type ii and iii secretion system protein
ETAA8_RS18695	COG2165	general secretion pathway protein
ETAA8_RS18705	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ETAA8_RS18740	COG0515	serine threonine protein kinase
ETAA8_RS18740	COG2815	serine threonine protein kinase
ETAA8_RS18755	COG3119	arylsulfatase activity
ETAA8_RS18760	COG3119	arylsulfatase activity
ETAA8_RS18790	COG1484	DNA-dependent DNA replication
ETAA8_RS18800	COG3265	gluconokinase activity
ETAA8_RS18820	COG3119	arylsulfatase activity
ETAA8_RS18825	COG3119	arylsulfatase activity
ETAA8_RS18850	COG1484	DNA-dependent DNA replication
ETAA8_RS18865	COG0515	serine threonine protein kinase
ETAA8_RS18865	COG2815	serine threonine protein kinase
ETAA8_RS18930	COG0657	acetylesterase activity
ETAA8_RS18945	COG3119	arylsulfatase activity
ETAA8_RS19015	COG1475	DNA binding
ETAA8_RS19050	COG1525	nuclease
ETAA8_RS19105	COG3119	arylsulfatase activity
ETAA8_RS19150	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ETAA8_RS19155	COG1074	ATP-dependent DNA helicase activity
ETAA8_RS19210	COG1475	DNA binding
ETAA8_RS19235	COG1475	DNA binding
ETAA8_RS19290	COG0745	RESPONSE REGULATOR receiver
ETAA8_RS19295	COG0643	Histidine kinase
ETAA8_RS19295	COG2198	Histidine kinase
ETAA8_RS19315	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ETAA8_RS19320	COG2201	protein-glutamate methylesterase activity
ETAA8_RS19325	COG2201	protein-glutamate methylesterase activity
ETAA8_RS19335	COG2205	protein histidine kinase activity
ETAA8_RS19335	COG0784	Response regulator, receiver
ETAA8_RS19340	COG0589	response to stress
ETAA8_RS19380	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ETAA8_RS19395	COG0732	type I restriction modification DNA specificity domain
ETAA8_RS19400	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
ETAA8_RS19435	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ETAA8_RS19485	COG3119	arylsulfatase activity
ETAA8_RS19500	COG3119	arylsulfatase activity
ETAA8_RS19505	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ETAA8_RS19520	COG2197	response regulator
ETAA8_RS19530	COG4585	Histidine kinase
ETAA8_RS19535	COG0469	pyruvate kinase activity
ETAA8_RS19540	COG3119	arylsulfatase activity
ETAA8_RS19550	COG3850	Histidine kinase
ETAA8_RS19550	COG5002	protein histidine kinase activity
ETAA8_RS19555	COG3119	arylsulfatase activity
ETAA8_RS19570	COG0446	pyridine nucleotide-disulphide oxidoreductase
ETAA8_RS19605	COG2197	response regulator
ETAA8_RS19610	COG4585	Histidine kinase
ETAA8_RS19640	COG0657	acetylesterase activity
ETAA8_RS19655	COG3119	arylsulfatase activity
ETAA8_RS19660	COG3119	arylsulfatase activity
ETAA8_RS19670	COG3119	arylsulfatase activity
ETAA8_RS19685	COG1335	isochorismatase
ETAA8_RS19690	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
ETAA8_RS19695	COG3976	FMN-binding domain protein
ETAA8_RS19695	COG1053	succinate dehydrogenase
ETAA8_RS19740	COG1073	alpha beta
ETAA8_RS19755	COG2226	methyltransferase
ETAA8_RS19785	COG0667	Aldo Keto reductase
ETAA8_RS19790	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ETAA8_RS19865	COG3119	arylsulfatase activity
ETAA8_RS19875	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ETAA8_RS19880	COG0596	Alpha beta hydrolase
ETAA8_RS19890	COG1858	cytochrome C peroxidase
ETAA8_RS19905	COG3059	membrane
ETAA8_RS19915	COG2204	response regulator
ETAA8_RS19935	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ETAA8_RS19940	COG0702	epimerase
ETAA8_RS19950	COG2815	serine threonine protein kinase
ETAA8_RS19950	COG0515	serine threonine protein kinase
ETAA8_RS19965	COG1484	DNA-dependent DNA replication
ETAA8_RS19995	COG1295	ribonuclease BN
ETAA8_RS19995	COG1959	2 iron, 2 sulfur cluster binding
ETAA8_RS20005	COG2015	COG2015, Alkyl sulfatase and related hydrolases
ETAA8_RS20010	COG3119	arylsulfatase activity
ETAA8_RS20025	COG1686	Belongs to the peptidase S11 family
ETAA8_RS20050	COG0589	response to stress
ETAA8_RS20080	COG3118	belongs to the thioredoxin family
ETAA8_RS20090	COG1484	DNA-dependent DNA replication
ETAA8_RS20105	COG2815	serine threonine protein kinase
ETAA8_RS20105	COG0515	serine threonine protein kinase
ETAA8_RS20135	COG0653	protein targeting
ETAA8_RS20150	COG1484	DNA-dependent DNA replication
ETAA8_RS20210	COG0515	serine threonine protein kinase
ETAA8_RS20210	COG2815	serine threonine protein kinase
ETAA8_RS20215	COG2124	cytochrome p450
ETAA8_RS20235	COG0482	sulfurtransferase activity
ETAA8_RS20240	COG0673	inositol 2-dehydrogenase activity
ETAA8_RS20255	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ETAA8_RS20315	COG0811	peptide transport
ETAA8_RS20320	COG0848	biopolymer transport protein
ETAA8_RS20365	COG3119	arylsulfatase activity
ETAA8_RS20370	COG3119	arylsulfatase activity
ETAA8_RS20375	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ETAA8_RS20390	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ETAA8_RS20400	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ETAA8_RS20415	COG1338	Plays a role in the flagellum-specific transport system
ETAA8_RS20425	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ETAA8_RS20480	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_RS20485	COG4864	UPF0365 protein
ETAA8_RS20495	COG2084	Dehydrogenase
ETAA8_RS20500	COG0515	serine threonine protein kinase
ETAA8_RS20500	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ETAA8_RS20525	COG1196	nuclear chromosome segregation
ETAA8_RS20560	COG0714	Associated with various cellular activities
ETAA8_RS20595	COG0442	prolyl-tRNA aminoacylation
ETAA8_RS20600	COG1668	transmembrane transport
ETAA8_RS20605	COG4555	ABC transporter
ETAA8_RS20620	COG0347	Belongs to the P(II) protein family
ETAA8_RS20625	COG0004	ammonium transporteR
ETAA8_RS20635	COG1994	Peptidase M50
ETAA8_RS20645	COG0714	Associated with various cellular activities
ETAA8_RS20675	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ETAA8_RS20690	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ETAA8_RS20710	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ETAA8_RS20725	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ETAA8_RS20740	COG3119	arylsulfatase activity
ETAA8_RS20785	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ETAA8_RS20850	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
ETAA8_RS20860	COG1477	protein flavinylation
ETAA8_RS20955	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ETAA8_RS20960	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ETAA8_RS20965	COG1620	l-lactate permease
ETAA8_RS20970	COG0574	Belongs to the PEP-utilizing enzyme family
ETAA8_RS20970	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ETAA8_RS20980	COG0589	response to stress
ETAA8_RS21005	COG2197	response regulator
ETAA8_RS21010	COG0583	DNA-binding transcription factor activity
ETAA8_RS21035	COG0175	sulfate reduction
ETAA8_RS21045	COG0583	DNA-binding transcription factor activity
ETAA8_RS21055	COG0501	Belongs to the peptidase M48B family
ETAA8_RS21070	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ETAA8_RS21085	COG1484	DNA-dependent DNA replication
ETAA8_RS21095	COG0469	pyruvate kinase activity
ETAA8_RS21105	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
ETAA8_RS21120	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_RS21130	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
ETAA8_RS21145	COG0702	epimerase
ETAA8_RS21165	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
ETAA8_RS21210	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ETAA8_RS21215	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ETAA8_RS21220	COG1595	DNA-templated transcription, initiation
ETAA8_RS21230	COG2080	2 iron, 2 sulfur cluster binding
ETAA8_RS21235	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ETAA8_RS21235	COG2080	2 iron, 2 sulfur cluster binding
ETAA8_RS21250	COG1940	carbohydrate kinase activity
ETAA8_RS21255	COG0481	GTPase activity
ETAA8_RS21275	COG2382	esterase
ETAA8_RS21305	COG2165	general secretion pathway protein
ETAA8_RS21325	COG2207	Transcriptional regulator
ETAA8_RS21325	COG1609	Transcriptional regulator
ETAA8_RS21355	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ETAA8_RS21360	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_RS21365	COG1846	Transcriptional regulator
ETAA8_RS21375	COG0045	succinate-CoA ligase (ADP-forming) activity
ETAA8_RS21400	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ETAA8_RS21410	COG1774	PSP1 C-terminal conserved region
ETAA8_RS21420	COG0528	UMP kinase activity
ETAA8_RS21435	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ETAA8_RS21465	COG0552	protein localization to endoplasmic reticulum
ETAA8_RS21470	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ETAA8_RS21480	COG1172	Belongs to the binding-protein-dependent transport system permease family
ETAA8_RS21485	COG1879	ABC-type sugar transport system periplasmic component
ETAA8_RS21490	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ETAA8_RS21495	COG0515	serine threonine protein kinase
ETAA8_RS21505	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ETAA8_RS21525	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ETAA8_RS21540	COG0617	tRNA 3'-terminal CCA addition
ETAA8_RS21600	COG2815	serine threonine protein kinase
ETAA8_RS21600	COG0515	serine threonine protein kinase
ETAA8_RS21660	COG2610	gluconate transmembrane transporter activity
ETAA8_RS21710	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ETAA8_RS21730	COG0515	serine threonine protein kinase
ETAA8_RS21730	COG2815	serine threonine protein kinase
ETAA8_RS21875	COG1073	alpha beta
ETAA8_RS21890	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ETAA8_RS21930	COG1484	DNA-dependent DNA replication
ETAA8_RS21960	COG2045	Belongs to the ComB family
ETAA8_RS21970	COG0114	fumarate hydratase activity
ETAA8_RS21980	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ETAA8_RS22005	COG3132	Protein of unknown function, DUF480
ETAA8_RS22010	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ETAA8_RS22015	COG0017	Asparaginyl-tRNA synthetase
ETAA8_RS22025	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ETAA8_RS22135	COG0667	Aldo Keto reductase
ETAA8_RS22180	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ETAA8_RS22195	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ETAA8_RS22200	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ETAA8_RS22205	COG0649	NAD binding
ETAA8_RS22260	COG4974	Belongs to the 'phage' integrase family
ETAA8_RS22275	COG2255	four-way junction helicase activity
ETAA8_RS22345	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ETAA8_RS22395	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ETAA8_RS22400	COG1484	DNA-dependent DNA replication
ETAA8_RS22425	COG1139	Iron-sulfur cluster binding protein
ETAA8_RS22430	COG0277	FAD linked oxidase domain protein
ETAA8_RS22435	COG0277	FAD linked oxidase domain protein
ETAA8_RS22440	COG0247	lactate metabolic process
ETAA8_RS22450	COG0443	Heat shock 70 kDa protein
ETAA8_RS22455	COG0077	Prephenate dehydratase
ETAA8_RS22455	COG1605	Chorismate mutase
ETAA8_RS22460	COG1562	ergosterol biosynthetic process
ETAA8_RS22495	COG3604	Transcriptional regulator
ETAA8_RS22500	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ETAA8_RS22505	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ETAA8_RS22510	COG4208	sulfate ABC transporter
ETAA8_RS22530	COG2814	Major facilitator Superfamily
ETAA8_RS22535	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ETAA8_RS22545	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ETAA8_RS22550	COG1419	protein localization to endoplasmic reticulum
ETAA8_RS22555	COG0489	protein tyrosine kinase activity
ETAA8_RS22555	COG2151	metal-sulfur cluster biosynthetic enzyme
ETAA8_RS22565	COG1191	sigma factor activity
ETAA8_RS22590	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ETAA8_RS22595	COG2255	four-way junction helicase activity
ETAA8_RS22605	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA8_RS22635	COG0540	Belongs to the ATCase OTCase family
ETAA8_RS22640	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ETAA8_RS22645	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA8_RS22655	COG3119	arylsulfatase activity
ETAA8_RS22685	COG0824	Thioesterase
ETAA8_RS22710	COG4401	Chorismate mutase type I
ETAA8_RS22740	COG0384	phenazine biosynthesis protein PhzF
ETAA8_RS22770	COG0657	acetylesterase activity
ETAA8_RS22785	COG2815	serine threonine protein kinase
ETAA8_RS22785	COG0515	serine threonine protein kinase
ETAA8_RS22790	COG0459	protein refolding
ETAA8_RS22795	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ETAA8_RS22800	COG0459	protein refolding
ETAA8_RS22805	COG0484	heat shock protein binding
ETAA8_RS22810	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ETAA8_RS22820	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
ETAA8_RS22845	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ETAA8_RS22860	COG1404	Belongs to the peptidase S8 family
ETAA8_RS22875	COG2020	methyltransferase activity
ETAA8_RS22880	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
ETAA8_RS22890	COG0363	glucosamine-6-phosphate deaminase activity
ETAA8_RS22900	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA8_RS22905	COG1764	response to oxidative stress
ETAA8_RS22910	COG0546	phosphoglycolate phosphatase activity
ETAA8_RS22915	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ETAA8_RS22920	COG0402	S-adenosylhomocysteine deaminase activity
ETAA8_RS22925	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ETAA8_RS22930	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ETAA8_RS22935	COG4864	UPF0365 protein
ETAA8_RS22950	COG0386	Belongs to the glutathione peroxidase family
ETAA8_RS22955	COG0047	phosphoribosylformylglycinamidine synthase activity
ETAA8_RS22980	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
ETAA8_RS22995	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ETAA8_RS23005	COG0107	imidazoleglycerol-phosphate synthase activity
ETAA8_RS23025	COG0793	Belongs to the peptidase S41A family
ETAA8_RS23030	COG0799	negative regulation of ribosome biogenesis
ETAA8_RS23035	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ETAA8_RS23035	COG0758	DNA mediated transformation
ETAA8_RS23040	COG4566	intracellular signal transduction
ETAA8_RS23045	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ETAA8_RS23060	COG0018	arginyl-trna synthetase
ETAA8_RS23105	COG1129	ABC transporter
ETAA8_RS23110	COG4214	carbohydrate transport
ETAA8_RS23155	COG0714	Associated with various cellular activities
ETAA8_RS23180	COG0138	bifunctional purine biosynthesis protein purh
ETAA8_RS23210	COG0590	tRNA wobble adenosine to inosine editing
ETAA8_RS23215	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ETAA8_RS23220	COG1012	belongs to the aldehyde dehydrogenase family
ETAA8_RS23235	COG1953	Uracil, thiamine, allantoin
ETAA8_RS23240	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ETAA8_RS23240	COG0167	dihydroorotate dehydrogenase activity
ETAA8_RS23245	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ETAA8_RS23265	COG1335	isochorismatase
ETAA8_RS23290	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ETAA8_RS23320	COG4968	Prepilin-type N-terminal cleavage methylation domain
ETAA8_RS23335	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ETAA8_RS23370	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ETAA8_RS23385	COG0561	phosphatase activity
ETAA8_RS23400	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ETAA8_RS23405	COG0228	four-way junction DNA binding
ETAA8_RS23410	COG0336	Belongs to the RNA methyltransferase TrmD family
ETAA8_RS23415	COG0335	large ribosomal subunit rRNA binding
ETAA8_RS23420	COG0792	nuclease activity
ETAA8_RS23465	COG0681	Belongs to the peptidase S26 family
ETAA8_RS23470	COG1137	ATPase activity
ETAA8_RS23475	COG0745	RESPONSE REGULATOR receiver
ETAA8_RS23480	COG1408	metallophosphoesterase
ETAA8_RS23485	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ETAA8_RS23515	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ETAA8_RS23525	COG1063	alcohol dehydrogenase
ETAA8_RS23535	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ETAA8_RS23545	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA8_RS23550	COG0454	-acetyltransferase
ETAA8_RS23550	COG0456	acetyltransferase
ETAA8_RS23560	COG2816	NAD+ diphosphatase activity
ETAA8_RS23585	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ETAA8_RS23590	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ETAA8_RS23595	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ETAA8_RS23605	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ETAA8_RS23620	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ETAA8_RS23620	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ETAA8_RS23645	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA8_RS23660	COG1132	(ABC) transporter
ETAA8_RS23670	COG0714	Associated with various cellular activities
ETAA8_RS23740	COG0667	Aldo Keto reductase
ETAA8_RS23745	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ETAA8_RS23755	COG0473	3-isopropylmalate dehydrogenase activity
ETAA8_RS23810	COG0673	inositol 2-dehydrogenase activity
ETAA8_RS23840	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ETAA8_RS23855	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ETAA8_RS23865	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ETAA8_RS23885	COG2258	MOSC domain
ETAA8_RS23900	COG2059	Chromate
ETAA8_RS23985	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ETAA8_RS23990	COG3119	arylsulfatase activity
ETAA8_RS24000	COG0714	Associated with various cellular activities
ETAA8_RS24005	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ETAA8_RS24010	COG0305	Participates in initiation and elongation during chromosome replication
ETAA8_RS24015	COG0359	binds to the 23S rRNA
ETAA8_RS24020	COG0629	single-stranded DNA binding
ETAA8_RS24025	COG0360	Binds together with S18 to 16S ribosomal RNA
ETAA8_RS24030	COG0193	aminoacyl-tRNA hydrolase activity
ETAA8_RS24035	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ETAA8_RS24060	COG2755	lipolytic protein G-D-S-L family
ETAA8_RS24070	COG1217	gtp-binding protein TYPA
ETAA8_RS24085	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ETAA8_RS24090	COG0328	RNA-DNA hybrid ribonuclease activity
ETAA8_RS24095	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ETAA8_RS24105	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ETAA8_RS24115	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA8_RS24120	COG1331	Highly conserved protein containing a thioredoxin domain
ETAA8_RS24125	COG3193	protein, possibly involved in utilization of glycolate and propanediol
ETAA8_RS24150	COG0203	ribosomal protein L17
ETAA8_RS24155	COG0202	RNA polymerase activity
ETAA8_RS24160	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ETAA8_RS24165	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ETAA8_RS24175	COG0343	queuine tRNA-ribosyltransferase activity
ETAA8_RS24230	COG0704	Plays a role in the regulation of phosphate uptake
ETAA8_RS24240	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ETAA8_RS24245	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ETAA8_RS24255	COG4869	propanediol catabolic process
ETAA8_RS24265	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
ETAA8_RS24270	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ETAA8_RS24275	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
ETAA8_RS24285	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
ETAA8_RS24305	COG0039	L-malate dehydrogenase activity
ETAA8_RS24310	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
ETAA8_RS24320	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ETAA8_RS24355	COG3119	arylsulfatase activity
ETAA8_RS24365	COG0328	RNA-DNA hybrid ribonuclease activity
ETAA8_RS24380	COG0181	hydroxymethylbilane synthase activity
ETAA8_RS24390	COG2239	Acts as a magnesium transporter
ETAA8_RS24400	COG1132	(ABC) transporter
ETAA8_RS24420	COG0420	3'-5' exonuclease activity
ETAA8_RS24425	COG4717	serine-type aminopeptidase activity
ETAA8_RS24435	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ETAA8_RS24440	COG0515	serine threonine protein kinase
ETAA8_RS24475	COG1891	lyase activity
ETAA8_RS24490	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ETAA8_RS24490	COG4797	methyltransferase
ETAA8_RS24495	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA8_RS24505	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ETAA8_RS24535	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ETAA8_RS24550	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ETAA8_RS24560	COG0489	protein tyrosine kinase activity
ETAA8_RS24590	COG1702	phosphate starvation-inducible protein PhoH
ETAA8_RS24595	COG1480	7TM receptor with intracellular HD hydrolase
ETAA8_RS24600	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ETAA8_RS24665	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_RS24670	COG0788	formyltetrahydrofolate deformylase activity
ETAA8_RS24675	COG0154	amidase activity
ETAA8_RS24680	COG0584	glycerophosphoryl diester phosphodiesterase
ETAA8_RS24705	COG0464	growth
ETAA8_RS24720	COG0745	RESPONSE REGULATOR receiver
ETAA8_RS24725	COG5002	protein histidine kinase activity
ETAA8_RS24735	COG5002	protein histidine kinase activity
ETAA8_RS24750	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ETAA8_RS24775	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ETAA8_RS24785	COG2165	general secretion pathway protein
ETAA8_RS24790	COG1573	uracil-dna glycosylase
ETAA8_RS24795	COG0693	protein deglycase activity
ETAA8_RS24835	COG2124	cytochrome p450
ETAA8_RS24840	COG2081	HI0933 family
ETAA8_RS24855	COG0066	3-isopropylmalate dehydratase activity
ETAA8_RS24860	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ETAA8_RS24885	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ETAA8_RS24910	COG2326	polyphosphate kinase activity
ETAA8_RS24920	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ETAA8_RS24925	COG2308	Evidence 4 Homologs of previously reported genes of
ETAA8_RS24940	COG1305	Transglutaminase-like
ETAA8_RS24980	COG0826	peptidase U32
ETAA8_RS24985	COG4191	Histidine kinase
ETAA8_RS24990	COG1185	polyribonucleotide nucleotidyltransferase activity
ETAA8_RS24995	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ETAA8_RS25000	COG1418	mRNA catabolic process
ETAA8_RS25075	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ETAA8_RS25125	COG0434	BtpA family
ETAA8_RS25175	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ETAA8_RS25180	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
ETAA8_RS25185	COG0149	triose-phosphate isomerase activity
ETAA8_RS25195	COG1561	YicC-like family, N-terminal region
ETAA8_RS25200	COG0194	GDP metabolic process
ETAA8_RS25205	COG1758	RNA polymerase activity
ETAA8_RS25210	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ETAA8_RS25225	COG1104	cysteine desulfurase activity
ETAA8_RS25240	COG2226	methyltransferase
ETAA8_RS25245	COG1606	tRNA processing
ETAA8_RS25250	COG1129	ABC transporter
ETAA8_RS25250	COG0842	Transport permease protein
ETAA8_RS25255	COG1131	(ABC) transporter
ETAA8_RS25270	COG2815	serine threonine protein kinase
ETAA8_RS25270	COG0515	serine threonine protein kinase
ETAA8_RS25280	COG3119	arylsulfatase activity
ETAA8_RS25285	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ETAA8_RS25305	COG1609	Transcriptional regulator
ETAA8_RS25325	COG0628	permease
ETAA8_RS25335	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ETAA8_RS25340	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ETAA8_RS25375	COG0714	Associated with various cellular activities
ETAA8_RS25420	COG2088	sporulation resulting in formation of a cellular spore
ETAA8_RS25425	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ETAA8_RS25435	COG0657	acetylesterase activity
ETAA8_RS25435	COG2755	lipolytic protein G-D-S-L family
ETAA8_RS25445	COG4968	Prepilin-type N-terminal cleavage methylation domain
ETAA8_RS25450	COG4968	Prepilin-type N-terminal cleavage methylation domain
ETAA8_RS25460	COG2165	general secretion pathway protein
ETAA8_RS25495	COG2204	response regulator
ETAA8_RS25505	COG2037	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)
ETAA8_RS25515	COG1104	cysteine desulfurase activity
ETAA8_RS25545	COG1404	Belongs to the peptidase S8 family
ETAA8_RS25555	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ETAA8_RS25570	COG1321	iron dependent repressor
ETAA8_RS25580	COG2204	response regulator
ETAA8_RS25585	COG2197	response regulator
ETAA8_RS25590	COG4974	Belongs to the 'phage' integrase family
ETAA8_RS25640	COG1639	'signal transduction protein
ETAA8_RS25655	COG3119	arylsulfatase activity
ETAA8_RS25670	COG4948	Mandelate Racemase Muconate Lactonizing
ETAA8_RS25675	COG4948	Mandelate Racemase Muconate Lactonizing
ETAA8_RS25685	COG1477	protein flavinylation
ETAA8_RS25690	COG0445	tRNA wobble uridine modification
ETAA8_RS25710	COG0523	cobalamin synthesis protein
ETAA8_RS25720	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ETAA8_RS25740	COG0714	Associated with various cellular activities
ETAA8_RS25775	COG0277	FAD linked oxidase domain protein
ETAA8_RS25835	COG4149	molybdate abc transporter
ETAA8_RS25840	COG0725	ABC transporter, periplasmic molybdate-binding protein
ETAA8_RS25940	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ETAA8_RS25950	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ETAA8_RS25955	COG0072	phenylalanine-tRNA ligase activity
ETAA8_RS25960	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ETAA8_RS25965	COG0473	3-isopropylmalate dehydrogenase activity
ETAA8_RS25965	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ETAA8_RS25975	COG0372	Belongs to the citrate synthase family
ETAA8_RS25980	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ETAA8_RS25985	COG0602	queuosine metabolic process
ETAA8_RS25990	COG5002	protein histidine kinase activity
ETAA8_RS26005	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ETAA8_RS26010	COG1459	type II secretion system
ETAA8_RS26020	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ETAA8_RS26045	COG0724	RNA recognition motif
ETAA8_RS26060	COG0142	geranyltranstransferase activity
ETAA8_RS26070	COG2814	Major facilitator Superfamily
ETAA8_RS26075	COG0519	Catalyzes the synthesis of GMP from XMP
ETAA8_RS26075	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ETAA8_RS26095	COG4122	O-methyltransferase activity
ETAA8_RS26130	COG3119	arylsulfatase activity
ETAA8_RS26165	COG2226	methyltransferase
ETAA8_RS26170	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA8_RS26180	COG0673	inositol 2-dehydrogenase activity
ETAA8_RS26185	COG1063	alcohol dehydrogenase
ETAA8_RS26190	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ETAA8_RS26195	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ETAA8_RS26200	COG0131	Imidazoleglycerol-phosphate dehydratase
ETAA8_RS26210	COG0205	6-phosphofructokinase activity
ETAA8_RS26215	COG0793	Belongs to the peptidase S41A family
ETAA8_RS26220	COG0009	L-threonylcarbamoyladenylate synthase
ETAA8_RS26300	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ETAA8_RS26305	COG1166	arginine decarboxylase activity
ETAA8_RS26335	COG0793	Belongs to the peptidase S41A family
ETAA8_RS26340	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ETAA8_RS26355	COG0537	adenosine 5'-monophosphoramidase activity
ETAA8_RS26360	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ETAA8_RS26365	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ETAA8_RS26370	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ETAA8_RS26375	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ETAA8_RS26450	COG0300	oxidoreductase activity
ETAA8_RS26485	COG0544	peptidyl-prolyl cis-trans isomerase activity
ETAA8_RS26490	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA8_RS26495	COG0495	leucyl-tRNA aminoacylation
ETAA8_RS26520	COG4566	intracellular signal transduction
ETAA8_RS26525	COG4191	Histidine kinase
ETAA8_RS26530	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
ETAA8_RS26560	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ETAA8_RS26565	COG0166	Belongs to the GPI family
ETAA8_RS26570	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
ETAA8_RS26580	COG0011	TIGRFAM Protein of
ETAA8_RS26585	COG0579	oxidoreductase
ETAA8_RS26590	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
ETAA8_RS26595	COG0686	Belongs to the AlaDH PNT family
ETAA8_RS26670	COG3781	membrane
ETAA8_RS26690	COG3852	Histidine kinase
ETAA8_RS26705	COG3852	Histidine kinase
ETAA8_RS26730	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ETAA8_RS26740	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_RS26780	COG0563	adenylate kinase activity
ETAA8_RS26785	COG0201	protein transport
ETAA8_RS26790	COG0200	Binds to the 23S rRNA
ETAA8_RS26795	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ETAA8_RS26800	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ETAA8_RS26805	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ETAA8_RS26810	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ETAA8_RS26815	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ETAA8_RS26820	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ETAA8_RS26825	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ETAA8_RS26830	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ETAA8_RS26835	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ETAA8_RS26840	COG0255	Belongs to the universal ribosomal protein uL29 family
ETAA8_RS26845	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ETAA8_RS26850	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ETAA8_RS26855	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ETAA8_RS26860	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ETAA8_RS26865	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ETAA8_RS26870	COG0089	rRNA binding
ETAA8_RS26875	COG0088	Forms part of the polypeptide exit tunnel
ETAA8_RS26880	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ETAA8_RS26885	COG0051	transcription antitermination factor activity, RNA binding
ETAA8_RS26910	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ETAA8_RS26920	COG0154	amidase activity
ETAA8_RS26930	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ETAA8_RS26930	COG0723	plastoquinol--plastocyanin reductase activity
ETAA8_RS26945	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ETAA8_RS27005	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ETAA8_RS27020	COG0250	Participates in transcription elongation, termination and antitermination
ETAA8_RS27025	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ETAA8_RS27030	COG0081	regulation of translation
ETAA8_RS27035	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ETAA8_RS27045	COG0085	RNA polymerase activity
ETAA8_RS27050	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ETAA8_RS27055	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ETAA8_RS27060	COG0049	tRNA binding
ETAA8_RS27065	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ETAA8_RS27075	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_RS27080	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ETAA8_RS27100	COG0302	gtp cyclohydrolase
ETAA8_RS27115	COG0277	FAD linked oxidase domain protein
ETAA8_RS27115	COG0247	lactate metabolic process
ETAA8_RS27125	COG0314	molybdopterin synthase activity
ETAA8_RS27130	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ETAA8_RS27135	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ETAA8_RS27175	COG0202	RNA polymerase activity
ETAA8_RS27190	COG3408	Glycogen debranching enzyme
ETAA8_RS27190	COG3119	arylsulfatase activity
ETAA8_RS27200	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ETAA8_RS27225	COG0646	methionine synthase
ETAA8_RS27225	COG1410	methionine synthase
ETAA8_RS27230	COG0861	Integral membrane protein TerC family
ETAA8_RS27255	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
ETAA8_RS27260	COG0515	serine threonine protein kinase
ETAA8_RS27260	COG2815	serine threonine protein kinase
ETAA8_RS27305	COG1301	dicarboxylic acid transport
ETAA8_RS27360	COG0835	chemotaxis
ETAA8_RS27375	COG0643	Histidine kinase
ETAA8_RS27375	COG2198	Histidine kinase
ETAA8_RS27385	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ETAA8_RS27390	COG2201	protein-glutamate methylesterase activity
ETAA8_RS27395	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETAA8_RS27400	COG4651	solute:proton antiporter activity
ETAA8_RS27400	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ETAA8_RS27430	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ETAA8_RS27460	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ETAA8_RS27460	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ETAA8_RS27460	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ETAA8_RS27465	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ETAA8_RS27550	COG0606	chelatase, subunit chli
ETAA8_RS27560	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ETAA8_RS27570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ETAA8_RS27605	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_RS27610	COG1595	DNA-templated transcription, initiation
ETAA8_RS27665	COG0179	Fumarylacetoacetate (FAA) hydrolase
ETAA8_RS27775	COG0515	serine threonine protein kinase
ETAA8_RS27775	COG2815	serine threonine protein kinase
ETAA8_RS27795	COG2197	response regulator
ETAA8_RS27810	COG1136	(ABC) transporter
ETAA8_RS27850	COG0459	protein refolding
ETAA8_RS27930	COG1475	DNA binding
ETAA8_RS27935	COG1192	Involved in chromosome partitioning
ETAA8_RS27960	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ETAA8_RS27970	COG0135	phosphoribosylanthranilate isomerase activity
ETAA8_RS27995	COG3409	Peptidoglycan-binding domain 1 protein
ETAA8_RS27995	COG3267	Type II secretory pathway component ExeA
ETAA8_RS28010	COG1216	Glycosyl transferase, family 2
ETAA8_RS28015	COG1477	protein flavinylation
ETAA8_RS28030	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ETAA8_RS28045	COG0513	Belongs to the DEAD box helicase family
ETAA8_RS28060	COG5002	protein histidine kinase activity
ETAA8_RS28065	COG0135	phosphoribosylanthranilate isomerase activity
ETAA8_RS28070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ETAA8_RS28075	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_RS28090	COG5433	transposase activity
ETAA8_RS28105	COG1678	Uncharacterized ACR, COG1678
ETAA8_RS28110	COG0583	DNA-binding transcription factor activity
ETAA8_RS28115	COG0753	catalase activity
ETAA8_RS28145	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ETAA8_RS28150	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ETAA8_RS28170	COG1012	belongs to the aldehyde dehydrogenase family
ETAA8_RS28175	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ETAA8_RS28190	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ETAA8_RS28225	COG1192	Involved in chromosome partitioning
ETAA8_RS28255	COG2957	Belongs to the agmatine deiminase family
ETAA8_RS28270	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ETAA8_RS28285	COG0439	Biotin carboxylase
ETAA8_RS28290	COG0511	ligase activity, forming carbon-carbon bonds
ETAA8_RS28305	COG1940	carbohydrate kinase activity
ETAA8_RS28310	COG1446	asparaginase
ETAA8_RS28315	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ETAA8_RS28335	COG1484	DNA-dependent DNA replication
ETAA8_RS28355	COG3604	Transcriptional regulator
ETAA8_RS28500	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ETAA8_RS28585	COG5507	3-demethylubiquinone-9 3-methyltransferase
ETAA8_RS28630	COG3311	Transcriptional regulator
ETAA8_RS28635	COG1569	PIN domain
ETAA8_RS28640	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ETAA8_RS28650	COG0859	PFAM glycosyl transferase family 9
ETAA8_RS28655	COG4786	Flagellar basal body rod
ETAA8_RS28660	COG4786	Flagellar basal body rod
ETAA8_RS28670	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
ETAA8_RS28675	COG1706	bacterial-type flagellum-dependent cell motility
ETAA8_RS28705	COG0811	peptide transport
ETAA8_RS28720	COG0358	DNA primase activity
ETAA8_RS28725	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ETAA8_RS28740	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ETAA8_RS28755	COG0191	fructose-bisphosphate aldolase activity
ETAA8_RS28760	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ETAA8_RS28775	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ETAA8_RS28800	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_RS28820	COG0515	serine threonine protein kinase
ETAA8_RS28820	COG2815	serine threonine protein kinase
ETAA8_RS28830	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ETAA8_RS28835	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ETAA8_RS28840	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETAA8_RS28850	COG0318	PFAM AMP-dependent synthetase and ligase
ETAA8_RS28890	COG0674	pyruvate-flavodoxin oxidoreductase activity
ETAA8_RS28890	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ETAA8_RS28895	COG1013	pyruvate-flavodoxin oxidoreductase activity
ETAA8_RS28920	COG0519	Catalyzes the synthesis of GMP from XMP
ETAA8_RS28940	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ETAA8_RS28945	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ETAA8_RS28960	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ETAA8_RS28975	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ETAA8_RS28980	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ETAA8_RS29040	COG3781	membrane
ETAA8_RS29050	COG0583	DNA-binding transcription factor activity
ETAA8_RS29055	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ETAA8_RS29075	COG2706	6-phosphogluconolactonase activity
ETAA8_RS29095	COG0405	Gamma-glutamyltransferase
ETAA8_RS29120	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ETAA8_RS29125	COG0242	peptide deformylase activity
ETAA8_RS29150	COG0747	negative chemotaxis
ETAA8_RS29155	COG0601	transmembrane transport
ETAA8_RS29160	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ETAA8_RS29170	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ETAA8_RS29175	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_RS29185	COG4964	Belongs to the GSP D family
ETAA8_RS29250	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ETAA8_RS29265	COG2204	response regulator
ETAA8_RS29270	COG3852	Histidine kinase
ETAA8_RS29275	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ETAA8_RS29285	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
ETAA8_RS29290	COG3119	arylsulfatase activity
ETAA8_RS29325	COG0714	Associated with various cellular activities
ETAA8_RS29330	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ETAA8_RS29335	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ETAA8_RS29345	COG2135	peptidase activity
ETAA8_RS29350	COG1012	belongs to the aldehyde dehydrogenase family
ETAA8_RS29355	COG1295	ribonuclease BN
ETAA8_RS29360	COG1760	l-serine dehydratase
ETAA8_RS29370	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ETAA8_RS29390	COG1132	(ABC) transporter
ETAA8_RS29400	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ETAA8_RS29405	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ETAA8_RS29420	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ETAA8_RS29425	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ETAA8_RS29430	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ETAA8_RS29460	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ETAA8_RS29480	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ETAA8_RS29500	COG0640	Transcriptional regulator
ETAA8_RS29650	COG0724	RNA recognition motif
ETAA8_RS29680	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA8_RS29695	COG1960	acyl-CoA dehydrogenase activity
ETAA8_RS29765	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ETAA8_RS29785	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ETAA8_RS29805	COG1657	PFAM Prenyltransferase squalene oxidase
ETAA8_RS29810	COG0322	excinuclease ABC activity
ETAA8_RS29830	COG1301	dicarboxylic acid transport
ETAA8_RS29855	COG1201	RNA secondary structure unwinding
ETAA8_RS29880	COG0142	geranyltranstransferase activity
ETAA8_RS29890	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ETAA8_RS29900	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ETAA8_RS29940	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ETAA8_RS29955	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ETAA8_RS29960	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ETAA8_RS29980	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ETAA8_RS29995	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ETAA8_RS29995	COG1918	ferrous iron import across plasma membrane
ETAA8_RS30010	COG0673	inositol 2-dehydrogenase activity
ETAA8_RS30030	COG1132	(ABC) transporter
ETAA8_RS30040	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ETAA8_RS30110	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ETAA8_RS30180	COG1191	sigma factor activity
ETAA8_RS30205	COG2353	YceI-like domain
ETAA8_RS30215	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ETAA8_RS30220	COG0575	Belongs to the CDS family
ETAA8_RS30275	COG1921	L-seryl-tRNASec selenium transferase activity
ETAA8_RS30320	COG4555	ABC transporter
ETAA8_RS30340	COG0714	Associated with various cellular activities
ETAA8_RS30350	COG3273	potassium ion transport
ETAA8_RS30350	COG0471	metal ion transport
ETAA8_RS30370	COG0297	glycogen (starch) synthase activity
ETAA8_RS30400	COG2271	Major facilitator Superfamily
ETAA8_RS30480	COG1070	Carbohydrate kinase
ETAA8_RS30530	COG1663	tetraacyldisaccharide 4'-kinase activity
ETAA8_RS30540	COG0529	Catalyzes the synthesis of activated sulfate
ETAA8_RS30610	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ETAA8_RS30615	COG0667	Aldo Keto reductase
ETAA8_RS30660	COG1459	type II secretion system
ETAA8_RS30665	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ETAA8_RS30675	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ETAA8_RS30690	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ETAA8_RS30695	COG1858	cytochrome C peroxidase
ETAA8_RS30705	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ETAA8_RS30725	COG2115	Belongs to the xylose isomerase family
ETAA8_RS30730	COG4585	Histidine kinase
ETAA8_RS30740	COG1181	Belongs to the D-alanine--D-alanine ligase family
ETAA8_RS30745	COG1181	Belongs to the D-alanine--D-alanine ligase family
ETAA8_RS30790	COG0564	pseudouridine synthase activity
ETAA8_RS30805	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA8_RS30815	COG0673	inositol 2-dehydrogenase activity
ETAA8_RS30845	COG0475	glutathione-regulated potassium exporter activity
ETAA8_RS30860	COG0811	peptide transport
ETAA8_RS30905	COG0673	inositol 2-dehydrogenase activity
ETAA8_RS30920	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ETAA8_RS30925	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ETAA8_RS30930	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ETAA8_RS30940	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ETAA8_RS30950	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ETAA8_RS30975	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ETAA8_RS30985	COG0631	protein serine/threonine phosphatase activity
ETAA8_RS30990	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ETAA8_RS30995	COG4566	intracellular signal transduction
ETAA8_RS31055	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
ETAA8_RS31065	COG4956	integral membrane protein (PIN domain superfamily)
ETAA8_RS31070	COG3706	GGDEF domain
ETAA8_RS31135	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ETAA8_RS31200	COG2226	methyltransferase
ETAA8_RS31240	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ETAA8_RS31270	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ETAA8_RS31275	COG1484	DNA-dependent DNA replication
ETAA8_RS31345	COG3335	DDE superfamily endonuclease
ETAA8_RS31360	COG2204	response regulator
ETAA8_RS31370	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
ETAA8_RS31375	COG4251	negative regulation of phosphorylation
ETAA8_RS31380	COG4251	negative regulation of phosphorylation
ETAA8_RS31385	COG2205	protein histidine kinase activity
ETAA8_RS31385	COG0784	Response regulator, receiver
ETAA8_RS31430	COG2815	serine threonine protein kinase
ETAA8_RS31430	COG0515	serine threonine protein kinase
ETAA8_RS31435	COG0515	serine threonine protein kinase
ETAA8_RS31435	COG2815	serine threonine protein kinase
ETAA8_RS31440	COG3119	arylsulfatase activity
ETAA8_RS31455	COG3119	arylsulfatase activity
ETAA8_RS31485	COG0105	UTP biosynthetic process
ETAA8_RS31490	COG0156	8-amino-7-oxononanoate synthase activity
ETAA8_RS31535	COG0640	Transcriptional regulator
ETAA8_RS31540	COG2154	pterin-4-alpha-carbinolamine dehydratase
ETAA8_RS31545	COG4221	oxidoreductase activity
ETAA8_RS31585	COG1643	Atp-dependent helicase
ETAA8_RS31610	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ETAA8_RS31655	COG0504	CTP synthase activity
ETAA8_RS31685	COG0531	amino acid
ETAA8_RS31700	COG0450	alkyl hydroperoxide reductase
ETAA8_RS31770	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ETAA8_RS31775	COG0542	response to heat
ETAA8_RS31780	COG3869	Catalyzes the specific phosphorylation of arginine residues in
ETAA8_RS31785	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ETAA8_RS31790	COG0215	cysteine-tRNA ligase activity
ETAA8_RS31795	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ETAA8_RS31800	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ETAA8_RS31805	COG0800	Aldolase
ETAA8_RS31820	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ETAA8_RS31840	COG0012	GTP binding
ETAA8_RS31865	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ETAA8_RS31870	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ETAA8_RS31880	COG0306	phosphate transporter
ETAA8_RS31885	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ETAA8_RS31890	COG4948	Mandelate Racemase Muconate Lactonizing
ETAA8_RS31915	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ETAA8_RS31920	COG0431	NADPH-dependent FMN reductase
ETAA8_RS31925	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ETAA8_RS31940	COG1073	alpha beta
ETAA8_RS31950	COG2205	protein histidine kinase activity
ETAA8_RS31950	COG0784	Response regulator, receiver
ETAA8_RS31980	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ETAA8_RS31995	COG0494	nUDIX hydrolase
ETAA8_RS32000	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ETAA8_RS32010	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ETAA8_RS32015	COG1611	Belongs to the LOG family
ETAA8_RS32030	COG2205	protein histidine kinase activity
ETAA8_RS32030	COG4999	Histidine kinase
ETAA8_RS32030	COG3850	Histidine kinase
ETAA8_RS32030	COG3437	response regulator, receiver
ETAA8_RS32045	COG0484	heat shock protein binding
ETAA8_RS32080	COG0129	dihydroxy-acid dehydratase activity
ETAA8_RS32090	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ETAA8_RS32100	COG0443	Heat shock 70 kDa protein
ETAA8_RS32105	COG3119	arylsulfatase activity
ETAA8_RS32125	COG0179	Fumarylacetoacetate (FAA) hydrolase
ETAA8_RS32200	COG0778	Nitroreductase
ETAA8_RS32205	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ETAA8_RS32210	COG0424	maF-like protein
ETAA8_RS32215	COG0564	pseudouridine synthase activity
ETAA8_RS32275	COG5002	protein histidine kinase activity
ETAA8_RS32295	COG0668	transmembrane transport
ETAA8_RS32330	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ETAA8_RS32375	COG1231	oxidoreductase activity
ETAA8_RS32390	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETAA8_RS32395	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ETAA8_RS32395	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ETAA8_RS32405	COG0095	Lipoate-protein ligase
ETAA8_RS32410	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ETAA8_RS32415	COG0823	Involved in the tonB-independent uptake of proteins
ETAA8_RS32415	COG4946	Tricorn protease homolog
ETAA8_RS32415	COG1506	peptidase
ETAA8_RS32425	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ETAA8_RS32430	COG2721	sulfolactate sulfo-lyase activity
ETAA8_RS32450	COG1228	amidohydrolase
ETAA8_RS32455	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ETAA8_RS32470	COG1030	water channel activity
ETAA8_RS32480	COG1131	(ABC) transporter
ETAA8_RS32490	COG0037	tRNA processing
ETAA8_RS32510	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ETAA8_RS32520	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA8_RS32525	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA8_RS32540	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ETAA8_RS32570	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ETAA8_RS32575	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ETAA8_RS32585	COG0109	protoheme IX farnesyltransferase activity
ETAA8_RS32590	COG1845	cytochrome c oxidase, subunit III
ETAA8_RS32605	COG2322	membrane
ETAA8_RS32725	COG0513	Belongs to the DEAD box helicase family
ETAA8_RS32730	COG1073	alpha beta
ETAA8_RS32740	COG1278	Cold shock
ETAA8_RS32750	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ETAA8_RS32755	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
ETAA8_RS32805	COG2205	protein histidine kinase activity
ETAA8_RS32805	COG0784	Response regulator, receiver
ETAA8_RS32835	COG0596	Alpha beta hydrolase
ETAA8_RS32905	COG3119	arylsulfatase activity
ETAA8_RS32910	COG3119	arylsulfatase activity
ETAA8_RS32915	COG3119	arylsulfatase activity
ETAA8_RS32930	COG1335	isochorismatase
ETAA8_RS32935	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
ETAA8_RS32955	COG3119	arylsulfatase activity
ETAA8_RS32990	COG1595	DNA-templated transcription, initiation
ETAA8_RS33020	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_RS33040	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ETAA8_RS33055	COG0583	DNA-binding transcription factor activity
ETAA8_RS33060	COG0067	glutamate synthase
ETAA8_RS33060	COG0069	glutamate synthase activity
ETAA8_RS33060	COG0070	glutamate synthase
ETAA8_RS33065	COG0493	'glutamate synthase
ETAA8_RS33070	COG2912	Transglutaminase-like superfamily
ETAA8_RS33105	COG1959	2 iron, 2 sulfur cluster binding
ETAA8_RS33115	COG2204	response regulator
ETAA8_RS33125	COG3852	Histidine kinase
ETAA8_RS33130	COG0745	RESPONSE REGULATOR receiver
ETAA8_RS33155	COG2304	oxidoreductase activity
ETAA8_RS33200	COG0584	glycerophosphoryl diester phosphodiesterase
ETAA8_RS33205	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ETAA8_RS33215	COG2195	Cleaves the N-terminal amino acid of tripeptides
ETAA8_RS33220	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ETAA8_RS33225	COG0471	metal ion transport
ETAA8_RS33225	COG0490	domain, Protein
ETAA8_RS33245	COG2066	Belongs to the glutaminase family
ETAA8_RS33270	COG2815	serine threonine protein kinase
ETAA8_RS33270	COG0515	serine threonine protein kinase
ETAA8_RS33285	COG0670	Belongs to the BI1 family
ETAA8_RS33305	COG0179	Fumarylacetoacetate (FAA) hydrolase
ETAA8_RS33310	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA8_RS33320	COG4206	TonB-dependent receptor
ETAA8_RS33330	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ETAA8_RS33385	COG2333	competence protein COMEC
ETAA8_RS33385	COG0658	competence protein
ETAA8_RS33425	COG0730	response to heat
ETAA8_RS33450	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ETAA8_RS33450	COG1796	DNA polymerase
ETAA8_RS33500	COG0662	Cupin 2, conserved barrel domain protein
ETAA8_RS33500	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
ETAA8_RS33515	COG4172	Belongs to the ABC transporter superfamily
ETAA8_RS33520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ETAA8_RS33525	COG0601	transmembrane transport
ETAA8_RS33535	COG2815	serine threonine protein kinase
ETAA8_RS33535	COG0515	serine threonine protein kinase
ETAA8_RS33555	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ETAA8_RS33560	COG0673	inositol 2-dehydrogenase activity
ETAA8_RS33580	COG0673	inositol 2-dehydrogenase activity
ETAA8_RS33585	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ETAA8_RS33590	COG2204	response regulator
ETAA8_RS33610	COG0745	RESPONSE REGULATOR receiver
ETAA8_RS33630	COG2895	sulfate adenylyltransferase (ATP) activity
ETAA8_RS33630	COG0529	Catalyzes the synthesis of activated sulfate
ETAA8_RS33640	COG0175	sulfate reduction
ETAA8_RS33655	COG0673	inositol 2-dehydrogenase activity
ETAA8_RS33660	COG1136	(ABC) transporter
ETAA8_RS33665	COG0577	efflux transmembrane transporter activity
ETAA8_RS33665	COG1136	(ABC) transporter
ETAA8_RS33680	COG0246	Mannitol dehydrogenase
ETAA8_RS33685	COG1063	alcohol dehydrogenase
ETAA8_RS33700	COG0673	inositol 2-dehydrogenase activity
ETAA8_RS33790	COG3842	ATPase activity
ETAA8_RS33815	COG2027	D-alanyl-D-alanine carboxypeptidase
ETAA8_RS33860	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ETAA8_RS33895	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
ETAA8_RS33905	COG2912	Transglutaminase-like superfamily
ETAA8_RS33930	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ETAA8_RS33970	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ETAA8_RS33985	COG0632	four-way junction helicase activity
ETAA8_RS33995	COG5492	domain, Protein
ETAA8_RS34010	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ETAA8_RS34020	COG1902	pentaerythritol trinitrate reductase activity
ETAA8_RS34040	COG4974	Belongs to the 'phage' integrase family
ETAA8_RS34045	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ETAA8_RS34055	COG1674	ftsk spoiiie
ETAA8_RS34060	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ETAA8_RS34065	COG1333	cytochrome c biogenesis protein
ETAA8_RS34065	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ETAA8_RS34080	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ETAA8_RS34090	COG0463	Glycosyl transferase, family 2
ETAA8_RS34105	COG0494	nUDIX hydrolase
ETAA8_RS34130	COG0557	exoribonuclease II activity
ETAA8_RS34140	COG1131	(ABC) transporter
ETAA8_RS34180	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ETAA8_RS34195	COG2442	InterPro IPR007367
ETAA8_RS34220	COG4717	serine-type aminopeptidase activity
ETAA8_RS34245	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ETAA8_RS34270	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ETAA8_RS34375	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA8_RS34545	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ETAA8_RS34580	COG1943	Transposase
ETAA8_RS34585	COG1187	pseudouridine synthase activity
ETAA8_RS34605	COG2329	Antibiotic biosynthesis monooxygenase
ETAA8_RS34635	COG0594	ribonuclease P activity
ETAA8_RS34675	COG0657	acetylesterase activity
ETAA8_RS34680	COG1294	oxidase, subunit
ETAA8_RS34705	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ETAA8_RS34890	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
ETAA8_RS35105	COG0653	protein targeting